WO2002030401A3 - Microchip reservoir devices and facilitated corrosion of electrodes - Google Patents

Microchip reservoir devices and facilitated corrosion of electrodes Download PDF

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Publication number
WO2002030401A3
WO2002030401A3 PCT/US2001/042698 US0142698W WO0230401A3 WO 2002030401 A3 WO2002030401 A3 WO 2002030401A3 US 0142698 W US0142698 W US 0142698W WO 0230401 A3 WO0230401 A3 WO 0230401A3
Authority
WO
WIPO (PCT)
Prior art keywords
electrode
potential
corrosion
metal
primary electrode
Prior art date
Application number
PCT/US2001/042698
Other languages
French (fr)
Other versions
WO2002030401A2 (en
Inventor
Norman F Sheppard Jr
Christina M Feakes
John T Santini Jr
Original Assignee
Microchips Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microchips Inc filed Critical Microchips Inc
Priority to AU2002224453A priority Critical patent/AU2002224453A1/en
Publication of WO2002030401A2 publication Critical patent/WO2002030401A2/en
Publication of WO2002030401A3 publication Critical patent/WO2002030401A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0097—Micromachined devices; Microelectromechanical systems [MEMS]; Devices obtained by lithographic treatment of silicon; Devices comprising chips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation

Abstract

Methods and devices are provided for enhancing corrosion of an electrode in a biocompatible fluid. The method comprises (1) placing a primary electrode and a counter electrode in an electroconductive biocompatible fluid to form an electrochemical cell; and (2) applying a time-varying potential, through the electrochemical cell, to the primary electrode. In a preferred embodiment, the primary electrode is metal and comprises a reservoir cap of a microchip device for the release of molecules or exposure of device reservoir contents. The potential preferably is characterized by a waveform having a maximum potential effectively anodic to meet or exceed the corrosion potential of the primary electrode. Also, the minimum potential preferably is effectively cathodic to be below the value where redeposition of metal ions on the metal electrode can substantially occur, thereby corroding the metal electrode.
PCT/US2001/042698 2000-10-11 2001-10-11 Microchip reservoir devices and facilitated corrosion of electrodes WO2002030401A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002224453A AU2002224453A1 (en) 2000-10-11 2001-10-11 Microchip reservoir devices and facilitated corrosion of electrodes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23937300P 2000-10-11 2000-10-11
US60/239,373 2000-10-11

Publications (2)

Publication Number Publication Date
WO2002030401A2 WO2002030401A2 (en) 2002-04-18
WO2002030401A3 true WO2002030401A3 (en) 2003-01-16

Family

ID=22901886

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/042698 WO2002030401A2 (en) 2000-10-11 2001-10-11 Microchip reservoir devices and facilitated corrosion of electrodes

Country Status (3)

Country Link
US (1) US6773429B2 (en)
AU (1) AU2002224453A1 (en)
WO (1) WO2002030401A2 (en)

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