WO2002044684A3 - Sample introduction device for mass spectrometry using a fast fluidic system to synchronize multiple parallel liquid sample streams - Google Patents

Sample introduction device for mass spectrometry using a fast fluidic system to synchronize multiple parallel liquid sample streams Download PDF

Info

Publication number
WO2002044684A3
WO2002044684A3 PCT/CA2001/001673 CA0101673W WO0244684A3 WO 2002044684 A3 WO2002044684 A3 WO 2002044684A3 CA 0101673 W CA0101673 W CA 0101673W WO 0244684 A3 WO0244684 A3 WO 0244684A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluid sample
introduction device
sample stream
mass spectrometry
multiple parallel
Prior art date
Application number
PCT/CA2001/001673
Other languages
French (fr)
Other versions
WO2002044684A2 (en
Inventor
Adam Weiss
Original Assignee
Mds Inc
Adam Weiss
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mds Inc, Adam Weiss filed Critical Mds Inc
Priority to AU2334302A priority Critical patent/AU2334302A/en
Priority to JP2002546183A priority patent/JP3917938B2/en
Priority to AT01998807T priority patent/ATE502391T1/en
Priority to AU2002223343A priority patent/AU2002223343B2/en
Priority to DE60144243T priority patent/DE60144243D1/en
Priority to CA002429007A priority patent/CA2429007C/en
Priority to EP01998807A priority patent/EP1338026B1/en
Priority to US10/432,965 priority patent/US6841774B1/en
Publication of WO2002044684A2 publication Critical patent/WO2002044684A2/en
Publication of WO2002044684A3 publication Critical patent/WO2002044684A3/en

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components

Abstract

ABSTRACT A sample introduction device for introducing a plurality of independent fluid sample streams into a mass spectrometer includes a manifold (84) having a plurality of fluid sample stream direct paths. Each direct path extends between a fluid sample stream inlet (80, 82) and a fluid sample stream outlet. A plurality of bypass paths (92, 96) is also provided in the manifold. Each bypass path is coupled to a respective one of the direct paths between the inlet and outlet. A plurality of transfer lines (86,94) is also provided with each transfer line being coupled to a respective one of the outlets to deliver a fluid sample stream to an ionization region of the mass spectrometer. A valve (90, 96) is positioned in each of the bypass paths and is actuable to divert the fluid sample stream entering the direct path via the inlet from the direct path and into the bypass path.
PCT/CA2001/001673 2000-11-28 2001-11-28 Sample introduction device for mass spectrometry using a fast fluidic system to synchronize multiple parallel liquid sample streams WO2002044684A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
AU2334302A AU2334302A (en) 2000-11-28 2001-11-28 Sample introduction device for mass spectrometry using a fast fluidic system to synchronize multiple parallel liquid sample streams
JP2002546183A JP3917938B2 (en) 2000-11-28 2001-11-28 Sample introduction device for mass spectrometry using a high-speed fluid system that synchronizes multiple parallel liquid sample flows
AT01998807T ATE502391T1 (en) 2000-11-28 2001-11-28 DEVICE FOR INTRODUCING LIQUID SAMPLES INTO A MASS SPECTROMETER USING A FAST VALVE SYSTEM FOR SYNCHRONIZING MULTIPLE PARALLEL SAMPLE STREAMS
AU2002223343A AU2002223343B2 (en) 2000-11-28 2001-11-28 Sample introduction device for mass spectrometry using a fast fluidic system to synchronize multiple parallel liquid sample streams
DE60144243T DE60144243D1 (en) 2000-11-28 2001-11-28 DEVICE FOR INTRODUCING LIQUID SAMPLES INTO A MASS SPECTROMETER USING A QUICK VALVE SYSTEM FOR SYNCHRONIZING MULTIPLE PARALLEL SAMPLES
CA002429007A CA2429007C (en) 2000-11-28 2001-11-28 Sample introduction device for mass spectrometry using a fast fluidic system to synchronize multiple parallel liquid sample streams
EP01998807A EP1338026B1 (en) 2000-11-28 2001-11-28 Sample introduction device for mass spectrometry using a fast fluidic system to synchronize multiple parallel liquid sample streams
US10/432,965 US6841774B1 (en) 2000-11-28 2001-11-28 Sample introduction device for mass spectrometry using a fast fluidic system to synchronize multiple parallel liquid sample streams

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25361600P 2000-11-28 2000-11-28
US60/253,616 2000-11-28
US27006701P 2001-02-20 2001-02-20
US60/270,067 2001-02-20

Publications (2)

Publication Number Publication Date
WO2002044684A2 WO2002044684A2 (en) 2002-06-06
WO2002044684A3 true WO2002044684A3 (en) 2003-02-27

Family

ID=26943414

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2001/001673 WO2002044684A2 (en) 2000-11-28 2001-11-28 Sample introduction device for mass spectrometry using a fast fluidic system to synchronize multiple parallel liquid sample streams

Country Status (7)

Country Link
EP (1) EP1338026B1 (en)
JP (1) JP3917938B2 (en)
AT (1) ATE502391T1 (en)
AU (2) AU2002223343B2 (en)
CA (1) CA2429007C (en)
DE (1) DE60144243D1 (en)
WO (1) WO2002044684A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7214320B1 (en) 2002-08-08 2007-05-08 Nanostream, Inc. Systems and methods for high throughput sample analysis
WO2004015411A1 (en) * 2002-08-08 2004-02-19 Nanostream, Inc. Systems and methods for high-throughput microfluidic sample analysis
US7132650B1 (en) 2003-09-26 2006-11-07 Nanostream, Inc. High throughput multi-dimensional sample analysis
US6987263B2 (en) * 2002-12-13 2006-01-17 Nanostream, Inc. High throughput systems and methods for parallel sample analysis
EP2285462B1 (en) 2008-05-27 2020-12-16 PerkinElmer Health Sciences, Inc. Method and device for modulating flow of a fluid in a chromatography system
CA2755966C (en) 2009-03-24 2017-11-07 Perkinelmer Health Sciences, Inc. Sorbent devices with longitudinal diffusion paths and methods of using them
US8388736B2 (en) 2009-10-02 2013-03-05 Perkinelmer Health Sciences, Inc. Sorbent devices and methods of using them
EP2580585B1 (en) 2010-06-14 2019-09-18 PerkinElmer Health Sciences, Inc. Fluidic devices and methods of using them
CN203935755U (en) 2010-09-22 2014-11-12 魄金莱默保健科学有限公司 For backpurge system and the device of chromatogram
US9241779B2 (en) 2012-11-02 2016-01-26 Coloplast A/S Male incontinence treatment system
US10111651B2 (en) 2012-11-02 2018-10-30 Coloplast A/S System and method of anchoring support material to tissue
US9480546B2 (en) 2013-08-05 2016-11-01 Coloplast A/S Hysteropexy mesh apparatuses and methods
US9522000B2 (en) 2013-11-08 2016-12-20 Coloplast A/S System and a method for surgical suture fixation
JP6362161B2 (en) * 2014-05-27 2018-07-25 国立大学法人 名古屋工業大学 Mass spectrometer
WO2017004010A1 (en) 2015-06-30 2017-01-05 Perkinelmer Health Sciences, Inc. Chromatography systems with mobile phase generators
WO2017046849A1 (en) * 2015-09-14 2017-03-23 株式会社日立ハイテクノロジーズ Mass spectrometer
GB2572671B (en) 2019-02-01 2021-09-22 Agilent Technologies Inc Interface device between sample separation device and mass spectrometer having multiple sample capillaries
US20220250102A1 (en) * 2019-07-31 2022-08-11 National Institute Of Advanced Industrial Science And Technology Spray ionization device, analysis device, and surface coating device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0169469A2 (en) * 1984-07-27 1986-01-29 BASF Corporation Analytical apparatus
EP0886143A1 (en) * 1998-03-27 1998-12-23 SYNSORB Biotech Inc. Apparatus for screening compound libraries
US5872010A (en) * 1995-07-21 1999-02-16 Northeastern University Microscale fluid handling system
US6066848A (en) * 1998-06-09 2000-05-23 Combichem, Inc. Parallel fluid electrospray mass spectrometer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0169469A2 (en) * 1984-07-27 1986-01-29 BASF Corporation Analytical apparatus
US5872010A (en) * 1995-07-21 1999-02-16 Northeastern University Microscale fluid handling system
EP0886143A1 (en) * 1998-03-27 1998-12-23 SYNSORB Biotech Inc. Apparatus for screening compound libraries
US6066848A (en) * 1998-06-09 2000-05-23 Combichem, Inc. Parallel fluid electrospray mass spectrometer

Also Published As

Publication number Publication date
AU2334302A (en) 2002-06-11
EP1338026A2 (en) 2003-08-27
AU2002223343B2 (en) 2007-01-18
WO2002044684A2 (en) 2002-06-06
ATE502391T1 (en) 2011-04-15
JP2004525483A (en) 2004-08-19
EP1338026B1 (en) 2011-03-16
DE60144243D1 (en) 2011-04-28
CA2429007C (en) 2008-11-25
CA2429007A1 (en) 2002-06-06
JP3917938B2 (en) 2007-05-23

Similar Documents

Publication Publication Date Title
WO2002044684A3 (en) Sample introduction device for mass spectrometry using a fast fluidic system to synchronize multiple parallel liquid sample streams
WO2002095360A3 (en) Method and apparatus for multiple electrospray sample introduction
KR100515425B1 (en) Real time gas chromatography mass spectrometry
GB2426216A (en) A sample injector system for liquid chromatography
KR840001700A (en) Fluid transfer device
NO20030594D0 (en) Tap and air mixing nozzle for multiple flavors
CA2331855A1 (en) Plasma retention structure providing internal flow
BRPI0408657A (en) separating valve
JPH05288738A (en) Gas chromatograph apparatus
EP0992725A3 (en) Fluid diverter system
EP0836859A3 (en) Multi stage type flow rate switching device
CN109580852A (en) A kind of comprehensive two dimensional gas chromatography instrument and modulator approach
JPH10122498A (en) Device for transporting one of plural gases to equipment
WO2002084126A3 (en) Method and apparatus for injecting a chemical into a fluid stream
JP3758585B2 (en) Liquid chromatograph system
EP0819444A3 (en) Multi-stage type flow rate switching device
WO2004056441A3 (en) Method and apparatus for mixture separation
US20100186481A1 (en) Miniaturized Gas Chromatography Module with Pre-Stage Miniaturized Unit
WO2003016765A3 (en) Fluid distribution device
US5637787A (en) Gas chromatograph
CA2318193A1 (en) Mixing block for mixing multi-component reactive material coating systems and an apparatus using same
PT1049499E (en) Apparatus for Use in Extracting Elements Especially Exogenous Antibodies Presented in Blood or Plasma
WO2005031032A3 (en) Apparatus for conveying gases to and from a chamber
JPS58174846A (en) Specimen feeder for gas chromatograph
US6452673B1 (en) Multiple input flow cell with single fluid path

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2429007

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2002223343

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2001998807

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2002546183

Country of ref document: JP

WWP Wipo information: published in national office

Ref document number: 2001998807

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWE Wipo information: entry into national phase

Ref document number: 10432965

Country of ref document: US