WO2002056666A3 - A method of detecting ultrasound contrast agent in soft tissue, and quantitating blood perfusion through regions of tissue - Google Patents

A method of detecting ultrasound contrast agent in soft tissue, and quantitating blood perfusion through regions of tissue Download PDF

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Publication number
WO2002056666A3
WO2002056666A3 PCT/NO2001/000022 NO0100022W WO02056666A3 WO 2002056666 A3 WO2002056666 A3 WO 2002056666A3 NO 0100022 W NO0100022 W NO 0100022W WO 02056666 A3 WO02056666 A3 WO 02056666A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
contrast agent
regions
blood perfusion
ultrasound contrast
Prior art date
Application number
PCT/NO2001/000022
Other languages
French (fr)
Other versions
WO2002056666A2 (en
Inventor
Bjoern A J Angelsen
Original Assignee
Bjoern A J Angelsen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/766,328 external-priority patent/US6461303B2/en
Application filed by Bjoern A J Angelsen filed Critical Bjoern A J Angelsen
Publication of WO2002056666A2 publication Critical patent/WO2002056666A2/en
Publication of WO2002056666A3 publication Critical patent/WO2002056666A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48Diagnostic techniques
    • A61B8/481Diagnostic techniques involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01SRADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52023Details of receivers
    • G01S7/52036Details of receivers using analysis of echo signal for target characterisation
    • G01S7/52038Details of receivers using analysis of echo signal for target characterisation involving non-linear properties of the propagation medium or of the reflective target
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01SRADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52023Details of receivers
    • G01S7/52036Details of receivers using analysis of echo signal for target characterisation
    • G01S7/52038Details of receivers using analysis of echo signal for target characterisation involving non-linear properties of the propagation medium or of the reflective target
    • G01S7/52039Details of receivers using analysis of echo signal for target characterisation involving non-linear properties of the propagation medium or of the reflective target exploiting the non-linear response of a contrast enhancer, e.g. a contrast agent

Abstract

The present invention is directed to a method for detecting an ultrasound contrast agent in a soft tissue and quantitating blood perfusion through regions of tissue by detecting the contrast agent in the tissue.
PCT/NO2001/000022 2001-01-19 2001-01-22 A method of detecting ultrasound contrast agent in soft tissue, and quantitating blood perfusion through regions of tissue WO2002056666A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/766,328 US6461303B2 (en) 2000-01-19 2001-01-19 Method of detecting ultrasound contrast agent in soft tissue, and quantitating blood perfusion through regions of tissue
US09/766,328 2001-01-19

Publications (2)

Publication Number Publication Date
WO2002056666A2 WO2002056666A2 (en) 2002-07-25
WO2002056666A3 true WO2002056666A3 (en) 2003-02-27

Family

ID=25076118

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NO2001/000022 WO2002056666A2 (en) 2001-01-19 2001-01-22 A method of detecting ultrasound contrast agent in soft tissue, and quantitating blood perfusion through regions of tissue

Country Status (1)

Country Link
WO (1) WO2002056666A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8021303B2 (en) 2003-06-12 2011-09-20 Bracco Research Sa System for extracting morphological information through a perfusion assessment process
KR101025490B1 (en) * 2003-06-12 2011-04-04 브라코 인터내셔날 비.브이. Blood flow estimates through replenishment curve fitting in untrasound contrast imaging
EP1674038A1 (en) * 2004-12-23 2006-06-28 Bracco Research S.A. System for extracting morphological information through a perfusion assessment process
CA2588182C (en) 2004-12-23 2014-05-06 Bracco Research Sa A perfusion assessment method and system based on bolus administration
WO2006108868A1 (en) * 2005-04-14 2006-10-19 Bracco Research Sa Perfusion assessment based on animated perfusion imaging
US11769252B2 (en) 2018-07-30 2023-09-26 The Regents Of The University Of California Systems and methods for intra-procedure image-based flow quantification

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0451984A2 (en) * 1990-03-28 1991-10-16 Kabushiki Kaisha Toshiba Ultrasonic probe system
US5410205A (en) * 1993-02-11 1995-04-25 Hewlett-Packard Company Ultrasonic transducer having two or more resonance frequencies
EP0770352A1 (en) * 1995-10-10 1997-05-02 Advanced Technology Laboratories, Inc. Ultrasonic diagnostic imaging with contrast agents
US5724976A (en) * 1994-12-28 1998-03-10 Kabushiki Kaisha Toshiba Ultrasound imaging preferable to ultrasound contrast echography
WO1998047533A1 (en) * 1997-04-24 1998-10-29 Nycomed Imaging A.S. Ultrasound imaging of tissue perfusion by pulse energy disruption of contrast agent
US5957852A (en) * 1998-06-02 1999-09-28 Acuson Corporation Ultrasonic harmonic imaging system and method
EP0948931A2 (en) * 1998-03-31 1999-10-13 General Electric Company Ultrasound imaging using coded excitation on transmit and selective filtering on receive

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0451984A2 (en) * 1990-03-28 1991-10-16 Kabushiki Kaisha Toshiba Ultrasonic probe system
US5410205A (en) * 1993-02-11 1995-04-25 Hewlett-Packard Company Ultrasonic transducer having two or more resonance frequencies
US5724976A (en) * 1994-12-28 1998-03-10 Kabushiki Kaisha Toshiba Ultrasound imaging preferable to ultrasound contrast echography
EP0770352A1 (en) * 1995-10-10 1997-05-02 Advanced Technology Laboratories, Inc. Ultrasonic diagnostic imaging with contrast agents
WO1998047533A1 (en) * 1997-04-24 1998-10-29 Nycomed Imaging A.S. Ultrasound imaging of tissue perfusion by pulse energy disruption of contrast agent
EP0948931A2 (en) * 1998-03-31 1999-10-13 General Electric Company Ultrasound imaging using coded excitation on transmit and selective filtering on receive
US5957852A (en) * 1998-06-02 1999-09-28 Acuson Corporation Ultrasonic harmonic imaging system and method

Also Published As

Publication number Publication date
WO2002056666A2 (en) 2002-07-25

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