WO2002057415A3 - Method for altering cell fate - Google Patents

Method for altering cell fate Download PDF

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Publication number
WO2002057415A3
WO2002057415A3 PCT/US2001/047882 US0147882W WO02057415A3 WO 2002057415 A3 WO2002057415 A3 WO 2002057415A3 US 0147882 W US0147882 W US 0147882W WO 02057415 A3 WO02057415 A3 WO 02057415A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell fate
altering cell
cell
cell type
altering
Prior art date
Application number
PCT/US2001/047882
Other languages
French (fr)
Other versions
WO2002057415A2 (en
Inventor
Philippe Collas
James M Robl
Original Assignee
Nucleotech Llc
Philippe Collas
James M Robl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nucleotech Llc, Philippe Collas, James M Robl filed Critical Nucleotech Llc
Priority to EP01993249A priority Critical patent/EP1356277B1/en
Priority to JP2002558469A priority patent/JP4332348B2/en
Priority to AT01993249T priority patent/ATE555380T1/en
Priority to AU2002245101A priority patent/AU2002245101B2/en
Priority to CA2429954A priority patent/CA2429954C/en
Publication of WO2002057415A2 publication Critical patent/WO2002057415A2/en
Publication of WO2002057415A3 publication Critical patent/WO2002057415A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/04—Cells produced using nuclear transfer

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Transplantation (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention provides methods for altering the expression profile of a cell to convert the cell from one cell type to a desired cell type. These reprogrammed cells may be used in a variety of medical applicaiton for treating a mammal in need of a particular cell type.
PCT/US2001/047882 2000-12-22 2001-12-11 Method for altering cell fate WO2002057415A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP01993249A EP1356277B1 (en) 2000-12-22 2001-12-11 Method for altering cell fate
JP2002558469A JP4332348B2 (en) 2000-12-22 2001-12-11 How to change cell fate
AT01993249T ATE555380T1 (en) 2000-12-22 2001-12-11 METHOD FOR ALTERING THE FATE OF CELLS
AU2002245101A AU2002245101B2 (en) 2000-12-22 2001-12-11 Method for altering cell fate
CA2429954A CA2429954C (en) 2000-12-22 2001-12-11 Method for altering cell fate

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25815200P 2000-12-22 2000-12-22
US60/258,152 2000-12-22
US10/015,824 2001-12-10
US10/015,824 US20020142397A1 (en) 2000-12-22 2001-12-10 Methods for altering cell fate

Publications (2)

Publication Number Publication Date
WO2002057415A2 WO2002057415A2 (en) 2002-07-25
WO2002057415A3 true WO2002057415A3 (en) 2002-12-27

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/047882 WO2002057415A2 (en) 2000-12-22 2001-12-11 Method for altering cell fate

Country Status (7)

Country Link
US (2) US20020142397A1 (en)
EP (1) EP1356277B1 (en)
JP (2) JP4332348B2 (en)
AT (1) ATE555380T1 (en)
AU (1) AU2002245101B2 (en)
CA (1) CA2429954C (en)
WO (1) WO2002057415A2 (en)

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