WO2002060523A3 - Atrial fibrillation rf treatment device and method - Google Patents

Atrial fibrillation rf treatment device and method Download PDF

Info

Publication number
WO2002060523A3
WO2002060523A3 PCT/US2001/048776 US0148776W WO02060523A3 WO 2002060523 A3 WO2002060523 A3 WO 2002060523A3 US 0148776 W US0148776 W US 0148776W WO 02060523 A3 WO02060523 A3 WO 02060523A3
Authority
WO
WIPO (PCT)
Prior art keywords
heart
treatment device
tissue
atrial fibrillation
transmural lesion
Prior art date
Application number
PCT/US2001/048776
Other languages
French (fr)
Other versions
WO2002060523A2 (en
WO2002060523A9 (en
Inventor
Tony R Brown
Hein Nguyen
Suresh Wadhwani
Octavio V Adame
Michael D Laufer
Original Assignee
Tony R Brown
Hein Nguyen
Suresh Wadhwani
Octavio V Adame
Michael D Laufer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tony R Brown, Hein Nguyen, Suresh Wadhwani, Octavio V Adame, Michael D Laufer filed Critical Tony R Brown
Priority to AU2002248196A priority Critical patent/AU2002248196A1/en
Priority to EP01997075A priority patent/EP1349510A4/en
Publication of WO2002060523A2 publication Critical patent/WO2002060523A2/en
Publication of WO2002060523A9 publication Critical patent/WO2002060523A9/en
Publication of WO2002060523A3 publication Critical patent/WO2002060523A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1477Needle-like probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/06Electrodes for high-frequency therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0225Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument for clamping tissue, e.g. forceps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • A61B2018/1425Needle
    • A61B2018/143Needle multiple needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1475Electrodes retractable in or deployable from a housing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy

Abstract

A radiofrequency treatment device of the present invention includes one or two radio frequency electrode holders (42) each having multiple electrodes (44) arranged to create a transmural lesion through tissue. The treatment device is placed with one holder (42) on the endocardial surface of the heart and the other optional holder placed on the epicardial surface of the heart to form a bipolar arrangement of equally spaced parallel tissue penetrating electrodes. The invention creates a transmural lesion in heart tissue to treat atrial fibrillation by blocking passage of abnormal electrical currents through the heart tissue. The devices may also be used to apply other types of energy, including cryo, ultrasound, microwave, heat, or other electrical means of providing an interruption in abnormal electrical circuits.
PCT/US2001/048776 2000-12-15 2001-12-17 Atrial fibrillation rf treatment device and method WO2002060523A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002248196A AU2002248196A1 (en) 2000-12-15 2001-12-17 Atrial fibrillation rf treatment device and method
EP01997075A EP1349510A4 (en) 2000-12-15 2001-12-17 Atrial fibrillation rf treatment device and method

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25624500P 2000-12-15 2000-12-15
US60/256,245 2000-12-15
US28779801P 2001-04-30 2001-04-30
US60/287,798 2001-04-30

Publications (3)

Publication Number Publication Date
WO2002060523A2 WO2002060523A2 (en) 2002-08-08
WO2002060523A9 WO2002060523A9 (en) 2002-11-28
WO2002060523A3 true WO2002060523A3 (en) 2003-05-08

Family

ID=26945224

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/048776 WO2002060523A2 (en) 2000-12-15 2001-12-17 Atrial fibrillation rf treatment device and method

Country Status (4)

Country Link
US (1) US6723092B2 (en)
EP (1) EP1349510A4 (en)
AU (1) AU2002248196A1 (en)
WO (1) WO2002060523A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9510899B2 (en) 2004-04-01 2016-12-06 The General Hospital Corporation Method and apparatus for dermatological treatment and tissue reshaping

Families Citing this family (229)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096037A (en) 1997-07-29 2000-08-01 Medtronic, Inc. Tissue sealing electrosurgery device and methods of sealing tissue
US6726686B2 (en) 1997-11-12 2004-04-27 Sherwood Services Ag Bipolar electrosurgical instrument for sealing vessels
US7435249B2 (en) 1997-11-12 2008-10-14 Covidien Ag Electrosurgical instruments which reduces collateral damage to adjacent tissue
US6228083B1 (en) 1997-11-14 2001-05-08 Sherwood Services Ag Laparoscopic bipolar electrosurgical instrument
US7364577B2 (en) 2002-02-11 2008-04-29 Sherwood Services Ag Vessel sealing system
US7582087B2 (en) 1998-10-23 2009-09-01 Covidien Ag Vessel sealing instrument
US7118570B2 (en) 2001-04-06 2006-10-10 Sherwood Services Ag Vessel sealing forceps with disposable electrodes
US6245062B1 (en) * 1998-10-23 2001-06-12 Afx, Inc. Directional reflector shield assembly for a microwave ablation instrument
US7267677B2 (en) 1998-10-23 2007-09-11 Sherwood Services Ag Vessel sealing instrument
US8285393B2 (en) * 1999-04-16 2012-10-09 Laufer Michael D Device for shaping infarcted heart tissue and method of using the device
US7226446B1 (en) * 1999-05-04 2007-06-05 Dinesh Mody Surgical microwave ablation assembly
US20030109875A1 (en) * 1999-10-22 2003-06-12 Tetzlaff Philip M. Open vessel sealing forceps with disposable electrodes
US20040162551A1 (en) * 2000-12-15 2004-08-19 Brown Tony R. Method and device for creating transmural lesions
US7740623B2 (en) 2001-01-13 2010-06-22 Medtronic, Inc. Devices and methods for interstitial injection of biologic agents into tissue
US20040138621A1 (en) 2003-01-14 2004-07-15 Jahns Scott E. Devices and methods for interstitial injection of biologic agents into tissue
DE60121229T2 (en) 2001-04-06 2007-05-24 Sherwood Services Ag DEVICE FOR SEALING AND SHARING A VESSEL WITH NON-LASTING END STOP
EP1527747B1 (en) 2001-04-06 2015-09-30 Covidien AG Electrosurgical instrument which reduces collateral damage to adjacent tissue
AU2002254712A1 (en) 2001-04-20 2002-11-05 Power Medical Interventions, Inc. Bipolar or ultrasonic surgical device
US7099717B2 (en) * 2002-01-03 2006-08-29 Afx Inc. Catheter having improved steering
US7967816B2 (en) * 2002-01-25 2011-06-28 Medtronic, Inc. Fluid-assisted electrosurgical instrument with shapeable electrode
US7291161B2 (en) * 2002-10-02 2007-11-06 Atricure, Inc. Articulated clamping member
US7270664B2 (en) 2002-10-04 2007-09-18 Sherwood Services Ag Vessel sealing instrument with electrical cutting mechanism
US7276068B2 (en) 2002-10-04 2007-10-02 Sherwood Services Ag Vessel sealing instrument with electrical cutting mechanism
US7931649B2 (en) 2002-10-04 2011-04-26 Tyco Healthcare Group Lp Vessel sealing instrument with electrical cutting mechanism
US20040082947A1 (en) * 2002-10-25 2004-04-29 The Regents Of The University Of Michigan Ablation catheters
US7799026B2 (en) 2002-11-14 2010-09-21 Covidien Ag Compressible jaw configuration with bipolar RF output electrodes for soft tissue fusion
US8021359B2 (en) 2003-02-13 2011-09-20 Coaptus Medical Corporation Transseptal closure of a patent foramen ovale and other cardiac defects
US7257450B2 (en) * 2003-02-13 2007-08-14 Coaptus Medical Corporation Systems and methods for securing cardiovascular tissue
EP1605866B1 (en) 2003-03-03 2016-07-06 Syntach AG Electrical conduction block implant device
US7776036B2 (en) * 2003-03-13 2010-08-17 Covidien Ag Bipolar concentric electrode assembly for soft tissue fusion
US6918907B2 (en) * 2003-03-13 2005-07-19 Boston Scientific Scimed, Inc. Surface electrode multiple mode operation
US7288092B2 (en) * 2003-04-23 2007-10-30 Atricure, Inc. Method and apparatus for ablating cardiac tissue with guide facility
US7160299B2 (en) 2003-05-01 2007-01-09 Sherwood Services Ag Method of fusing biomaterials with radiofrequency energy
CA2523675C (en) 2003-05-01 2016-04-26 Sherwood Services Ag Electrosurgical instrument which reduces thermal damage to adjacent tissue
AU2004241092B2 (en) 2003-05-15 2009-06-04 Covidien Ag Tissue sealer with non-conductive variable stop members and method of sealing tissue
US7156846B2 (en) 2003-06-13 2007-01-02 Sherwood Services Ag Vessel sealer and divider for use with small trocars and cannulas
USD956973S1 (en) 2003-06-13 2022-07-05 Covidien Ag Movable handle for endoscopic vessel sealer and divider
US7150749B2 (en) 2003-06-13 2006-12-19 Sherwood Services Ag Vessel sealer and divider having elongated knife stroke and safety cutting mechanism
US7857812B2 (en) 2003-06-13 2010-12-28 Covidien Ag Vessel sealer and divider having elongated knife stroke and safety for cutting mechanism
US20050080410A1 (en) * 2003-10-14 2005-04-14 Scimed Life Systems, Inc. Liquid infusion apparatus for radiofrequency tissue ablation
WO2005039689A2 (en) * 2003-10-24 2005-05-06 Sinus Rhythm Technologies, Inc. Methods and devices for creating cardiac electrical blocks
US9848938B2 (en) 2003-11-13 2017-12-26 Covidien Ag Compressible jaw configuration with bipolar RF output electrodes for soft tissue fusion
US7367976B2 (en) 2003-11-17 2008-05-06 Sherwood Services Ag Bipolar forceps having monopolar extension
SE526861C2 (en) 2003-11-17 2005-11-15 Syntach Ag Tissue lesion creation device and a set of devices for the treatment of cardiac arrhythmia disorders
US7500975B2 (en) 2003-11-19 2009-03-10 Covidien Ag Spring loaded reciprocating tissue cutting mechanism in a forceps-style electrosurgical instrument
US7811283B2 (en) 2003-11-19 2010-10-12 Covidien Ag Open vessel sealing instrument with hourglass cutting mechanism and over-ratchet safety
US7131970B2 (en) 2003-11-19 2006-11-07 Sherwood Services Ag Open vessel sealing instrument with cutting mechanism
US7442193B2 (en) 2003-11-20 2008-10-28 Covidien Ag Electrically conductive/insulative over-shoe for tissue fusion
JP2007519498A (en) 2004-01-30 2007-07-19 エヌエムティー メディカル, インコーポレイティッド Devices, systems, and methods for closure of cardiac openings
US7223267B2 (en) * 2004-02-06 2007-05-29 Misonix, Incorporated Ultrasonic probe with detachable slidable cauterization forceps
US9398967B2 (en) 2004-03-02 2016-07-26 Syntach Ag Electrical conduction block implant device
US7780662B2 (en) 2004-03-02 2010-08-24 Covidien Ag Vessel sealing system using capacitive RF dielectric heating
US7089515B2 (en) * 2004-03-09 2006-08-08 International Business Machines Corporation Threshold voltage roll-off compensation using back-gated MOSFET devices for system high-performance and low standby power
US7179254B2 (en) * 2004-03-09 2007-02-20 Ethicon, Inc. High intensity ablation device
US20080082090A1 (en) * 2004-04-01 2008-04-03 The General Hospital Corporation Method and apparatus for dermatological treatment and tissue reshaping
WO2005096980A1 (en) * 2004-04-05 2005-10-20 Ganz Robert A Device and method for treating tissue
US9011329B2 (en) 2004-04-19 2015-04-21 Searete Llc Lumenally-active device
US8512219B2 (en) 2004-04-19 2013-08-20 The Invention Science Fund I, Llc Bioelectromagnetic interface system
US7850676B2 (en) 2004-04-19 2010-12-14 The Invention Science Fund I, Llc System with a reservoir for perfusion management
US8361013B2 (en) 2004-04-19 2013-01-29 The Invention Science Fund I, Llc Telescoping perfusion management system
US8353896B2 (en) 2004-04-19 2013-01-15 The Invention Science Fund I, Llc Controllable release nasal system
US8337482B2 (en) * 2004-04-19 2012-12-25 The Invention Science Fund I, Llc System for perfusion management
EP1750608B1 (en) 2004-06-02 2012-10-03 Medtronic, Inc. Ablation device with jaws
US20060025761A1 (en) * 2004-07-29 2006-02-02 Riley Lee B Linear-array radio frequency resections
US20060047281A1 (en) * 2004-09-01 2006-03-02 Syneron Medical Ltd. Method and system for invasive skin treatment
US7195631B2 (en) 2004-09-09 2007-03-27 Sherwood Services Ag Forceps with spring loaded end effector assembly
US7540872B2 (en) 2004-09-21 2009-06-02 Covidien Ag Articulating bipolar electrosurgical instrument
US7473252B2 (en) * 2004-10-07 2009-01-06 Coaptus Medical Corporation Systems and methods for shrinking and/or securing cardiovascular tissue
US7955332B2 (en) 2004-10-08 2011-06-07 Covidien Ag Mechanism for dividing tissue in a hemostat-style instrument
US20060089637A1 (en) 2004-10-14 2006-04-27 Werneth Randell L Ablation catheter
US8617152B2 (en) 2004-11-15 2013-12-31 Medtronic Ablation Frontiers Llc Ablation system with feedback
US7429261B2 (en) 2004-11-24 2008-09-30 Ablation Frontiers, Inc. Atrial ablation catheter and method of use
US7468062B2 (en) 2004-11-24 2008-12-23 Ablation Frontiers, Inc. Atrial ablation catheter adapted for treatment of septal wall arrhythmogenic foci and method of use
US8029528B2 (en) * 2005-01-03 2011-10-04 Atricure, Inc. Instrument guide and method for use
US20060149121A1 (en) * 2005-01-03 2006-07-06 Hughett James D Sr Instrument guide and method for use
US7686804B2 (en) 2005-01-14 2010-03-30 Covidien Ag Vessel sealer and divider with rotating sealer and cutter
US20070156209A1 (en) * 2005-01-14 2007-07-05 Co-Repair, Inc. System for the treatment of heart tissue
US7455670B2 (en) * 2005-01-14 2008-11-25 Co-Repair, Inc. System and method for the treatment of heart tissue
US7909823B2 (en) 2005-01-14 2011-03-22 Covidien Ag Open vessel sealing instrument
US20070156210A1 (en) * 2005-01-14 2007-07-05 Co-Repair, Inc., A California Corporation Method for the treatment of heart tissue
US7491202B2 (en) 2005-03-31 2009-02-17 Covidien Ag Electrosurgical forceps with slow closure sealing plates and method of sealing tissue
US7850683B2 (en) * 2005-05-20 2010-12-14 Myoscience, Inc. Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat)
US7713266B2 (en) 2005-05-20 2010-05-11 Myoscience, Inc. Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat)
US7850685B2 (en) 2005-06-20 2010-12-14 Medtronic Ablation Frontiers Llc Ablation catheter
EP1909679B1 (en) 2005-07-11 2013-11-20 Medtronic Ablation Frontiers LLC Low power tissue ablation system
US8657814B2 (en) 2005-08-22 2014-02-25 Medtronic Ablation Frontiers Llc User interface for tissue ablation system
WO2007030433A2 (en) 2005-09-06 2007-03-15 Nmt Medical, Inc. Removable intracardiac rf device
US9259267B2 (en) 2005-09-06 2016-02-16 W.L. Gore & Associates, Inc. Devices and methods for treating cardiac tissue
US20070088388A1 (en) * 2005-09-19 2007-04-19 Opolski Steven W Delivery device for implant with dual attachment sites
US7789878B2 (en) 2005-09-30 2010-09-07 Covidien Ag In-line vessel sealer and divider
US7922953B2 (en) 2005-09-30 2011-04-12 Covidien Ag Method for manufacturing an end effector assembly
US7879035B2 (en) 2005-09-30 2011-02-01 Covidien Ag Insulating boot for electrosurgical forceps
CA2561034C (en) 2005-09-30 2014-12-09 Sherwood Services Ag Flexible endoscopic catheter with an end effector for coagulating and transfecting tissue
US7846161B2 (en) 2005-09-30 2010-12-07 Covidien Ag Insulating boot for electrosurgical forceps
US7722607B2 (en) 2005-09-30 2010-05-25 Covidien Ag In-line vessel sealer and divider
US7611512B2 (en) * 2005-10-12 2009-11-03 Moshe Ein-Gal Interleaved array of bipolar electrodes
US20070093804A1 (en) * 2005-10-17 2007-04-26 Coaptus Medical Corporation Control systems for patient devices, including devices for securing cardiovascular tissue, and associated methods
SI2926847T1 (en) * 2005-11-02 2022-10-28 Medicaltree Patents Ltd. Implantable infusion device with advanceable and retractable needle
US8298232B2 (en) 2006-01-24 2012-10-30 Tyco Healthcare Group Lp Endoscopic vessel sealer and divider for large tissue structures
US8882766B2 (en) 2006-01-24 2014-11-11 Covidien Ag Method and system for controlling delivery of energy to divide tissue
US8734443B2 (en) 2006-01-24 2014-05-27 Covidien Lp Vessel sealer and divider for large tissue structures
US8241282B2 (en) * 2006-01-24 2012-08-14 Tyco Healthcare Group Lp Vessel sealing cutting assemblies
US7776037B2 (en) 2006-07-07 2010-08-17 Covidien Ag System and method for controlling electrode gap during tissue sealing
US20080039879A1 (en) * 2006-08-09 2008-02-14 Chin Albert K Devices and methods for atrial appendage exclusion
US8597297B2 (en) 2006-08-29 2013-12-03 Covidien Ag Vessel sealing instrument with multiple electrode configurations
US7806449B2 (en) * 2006-08-31 2010-10-05 Micron Technology, Inc. Substrate pick
US8070746B2 (en) 2006-10-03 2011-12-06 Tyco Healthcare Group Lp Radiofrequency fusion of cardiac tissue
US20080140064A1 (en) * 2006-12-07 2008-06-12 Cierra, Inc. Energy delivery apparatus with tissue piercing thermocouple
US9254162B2 (en) 2006-12-21 2016-02-09 Myoscience, Inc. Dermal and transdermal cryogenic microprobe systems
US20080177258A1 (en) * 2007-01-18 2008-07-24 Assaf Govari Catheter with microphone
USD649249S1 (en) 2007-02-15 2011-11-22 Tyco Healthcare Group Lp End effectors of an elongated dissecting and dividing instrument
US8409185B2 (en) * 2007-02-16 2013-04-02 Myoscience, Inc. Replaceable and/or easily removable needle systems for dermal and transdermal cryogenic remodeling
US10166066B2 (en) 2007-03-13 2019-01-01 University Of Virginia Patent Foundation Epicardial ablation catheter and method of use
WO2008118737A1 (en) 2007-03-22 2008-10-02 University Of Virginia Patent Foundation Electrode catheter for ablation purposes and related method thereof
US9468396B2 (en) 2007-03-19 2016-10-18 University Of Virginia Patent Foundation Systems and methods for determining location of an access needle in a subject
US11058354B2 (en) 2007-03-19 2021-07-13 University Of Virginia Patent Foundation Access needle with direct visualization and related methods
CA2680639C (en) 2007-03-19 2017-03-07 University Of Virginia Patent Foundation Access needle pressure sensor device and method of use
ES2394719T3 (en) 2007-03-23 2013-02-05 Medtronic Advanced Energy Llc Electrosurgical device with distal disc with two electrodes and fluid outlet
US8267935B2 (en) 2007-04-04 2012-09-18 Tyco Healthcare Group Lp Electrosurgical instrument reducing current densities at an insulator conductor junction
US8641704B2 (en) 2007-05-11 2014-02-04 Medtronic Ablation Frontiers Llc Ablation therapy system and method for treating continuous atrial fibrillation
US8774892B2 (en) * 2007-06-05 2014-07-08 Med-El Elektromedizinische Geraete Gmbh Electrode configuration and measuring device for measuring the electrical activity in electrically active tissue
US20080312648A1 (en) * 2007-06-12 2008-12-18 Darion Peterson Fat removal and sculpting device
US7877852B2 (en) 2007-09-20 2011-02-01 Tyco Healthcare Group Lp Method of manufacturing an end effector assembly for sealing tissue
US7877853B2 (en) 2007-09-20 2011-02-01 Tyco Healthcare Group Lp Method of manufacturing end effector assembly for sealing tissue
US20090082766A1 (en) * 2007-09-20 2009-03-26 Tyco Healthcare Group Lp Tissue Sealer and End Effector Assembly and Method of Manufacturing Same
US8267936B2 (en) 2007-09-28 2012-09-18 Tyco Healthcare Group Lp Insulating mechanically-interfaced adhesive for electrosurgical forceps
US8241283B2 (en) 2007-09-28 2012-08-14 Tyco Healthcare Group Lp Dual durometer insulating boot for electrosurgical forceps
US8236025B2 (en) 2007-09-28 2012-08-07 Tyco Healthcare Group Lp Silicone insulated electrosurgical forceps
US8235993B2 (en) 2007-09-28 2012-08-07 Tyco Healthcare Group Lp Insulating boot for electrosurgical forceps with exohinged structure
US8251996B2 (en) 2007-09-28 2012-08-28 Tyco Healthcare Group Lp Insulating sheath for electrosurgical forceps
US9023043B2 (en) 2007-09-28 2015-05-05 Covidien Lp Insulating mechanically-interfaced boot and jaws for electrosurgical forceps
US8221416B2 (en) 2007-09-28 2012-07-17 Tyco Healthcare Group Lp Insulating boot for electrosurgical forceps with thermoplastic clevis
US8235992B2 (en) 2007-09-28 2012-08-07 Tyco Healthcare Group Lp Insulating boot with mechanical reinforcement for electrosurgical forceps
WO2009045265A1 (en) 2007-10-05 2009-04-09 Maquet Cardiovascular, Llc Devices and methods for minimally-invasive surgical procedures
EP2214562B1 (en) * 2007-11-05 2016-04-27 Erbe Elektromedizin GmbH Surgical instrument for sealing blood vessels, and heat-curable adhesive as a medicament
WO2009062061A1 (en) 2007-11-09 2009-05-14 University Of Virginia Patent Foundation Steerable epicardial pacing catheter system placed via the subxiphoid process
US8298216B2 (en) * 2007-11-14 2012-10-30 Myoscience, Inc. Pain management using cryogenic remodeling
KR101626167B1 (en) 2008-01-17 2016-05-31 시네론 메디컬 리미티드 A hair removal apparatus for personal use and the method of using same
JP2011509791A (en) 2008-01-24 2011-03-31 シネロン メディカル リミテッド Apparatus, device and method for adipose tissue treatment
US8764748B2 (en) 2008-02-06 2014-07-01 Covidien Lp End effector assembly for electrosurgical device and method for making the same
US8623276B2 (en) 2008-02-15 2014-01-07 Covidien Lp Method and system for sterilizing an electrosurgical instrument
US20100017750A1 (en) * 2008-07-16 2010-01-21 Avner Rosenberg User interface
US9314293B2 (en) * 2008-07-16 2016-04-19 Syneron Medical Ltd RF electrode for aesthetic and body shaping devices and method of using same
US8469956B2 (en) 2008-07-21 2013-06-25 Covidien Lp Variable resistor jaw
US8257387B2 (en) 2008-08-15 2012-09-04 Tyco Healthcare Group Lp Method of transferring pressure in an articulating surgical instrument
US8162973B2 (en) 2008-08-15 2012-04-24 Tyco Healthcare Group Lp Method of transferring pressure in an articulating surgical instrument
US9603652B2 (en) 2008-08-21 2017-03-28 Covidien Lp Electrosurgical instrument including a sensor
US8317787B2 (en) 2008-08-28 2012-11-27 Covidien Lp Tissue fusion jaw angle improvement
US8784417B2 (en) 2008-08-28 2014-07-22 Covidien Lp Tissue fusion jaw angle improvement
US8795274B2 (en) 2008-08-28 2014-08-05 Covidien Lp Tissue fusion jaw angle improvement
US8303582B2 (en) 2008-09-15 2012-11-06 Tyco Healthcare Group Lp Electrosurgical instrument having a coated electrode utilizing an atomic layer deposition technique
US20100069903A1 (en) * 2008-09-18 2010-03-18 Tyco Healthcare Group Lp Vessel Sealing Instrument With Cutting Mechanism
KR101523807B1 (en) * 2008-09-21 2015-05-28 시네론 메디컬 리미티드 A method and apparatus for personal skin treatment
US8968314B2 (en) 2008-09-25 2015-03-03 Covidien Lp Apparatus, system and method for performing an electrosurgical procedure
US8535312B2 (en) 2008-09-25 2013-09-17 Covidien Lp Apparatus, system and method for performing an electrosurgical procedure
US9375254B2 (en) 2008-09-25 2016-06-28 Covidien Lp Seal and separate algorithm
US8142473B2 (en) 2008-10-03 2012-03-27 Tyco Healthcare Group Lp Method of transferring rotational motion in an articulating surgical instrument
US8469957B2 (en) 2008-10-07 2013-06-25 Covidien Lp Apparatus, system, and method for performing an electrosurgical procedure
US8016827B2 (en) 2008-10-09 2011-09-13 Tyco Healthcare Group Lp Apparatus, system, and method for performing an electrosurgical procedure
US8636761B2 (en) 2008-10-09 2014-01-28 Covidien Lp Apparatus, system, and method for performing an endoscopic electrosurgical procedure
US8486107B2 (en) 2008-10-20 2013-07-16 Covidien Lp Method of sealing tissue using radiofrequency energy
US8197479B2 (en) 2008-12-10 2012-06-12 Tyco Healthcare Group Lp Vessel sealer and divider
EP2373239B1 (en) 2008-12-22 2013-08-14 Myoscience, Inc. Integrated cryosurgical system with refrigerant and electrical power source
US8114122B2 (en) 2009-01-13 2012-02-14 Tyco Healthcare Group Lp Apparatus, system, and method for performing an electrosurgical procedure
US20100211055A1 (en) * 2009-02-18 2010-08-19 Shimon Eckhouse Method for body toning and an integrated data management system for the same
US9278230B2 (en) 2009-02-25 2016-03-08 Syneron Medical Ltd Electrical skin rejuvenation
US8915908B2 (en) * 2009-03-20 2014-12-23 Atricure, Inc. Cryogenic probe
US20100249769A1 (en) * 2009-03-24 2010-09-30 Tyco Healthcare Group Lp Apparatus for Tissue Sealing
US8187273B2 (en) 2009-05-07 2012-05-29 Tyco Healthcare Group Lp Apparatus, system, and method for performing an electrosurgical procedure
US8246618B2 (en) 2009-07-08 2012-08-21 Tyco Healthcare Group Lp Electrosurgical jaws with offset knife
US9642534B2 (en) 2009-09-11 2017-05-09 University Of Virginia Patent Foundation Systems and methods for determining location of an access needle in a subject
US8133254B2 (en) 2009-09-18 2012-03-13 Tyco Healthcare Group Lp In vivo attachable and detachable end effector assembly and laparoscopic surgical instrument and methods therefor
US8361069B2 (en) * 2009-09-25 2013-01-29 Covidien Lp Energized needles for wound sealing
US8112871B2 (en) 2009-09-28 2012-02-14 Tyco Healthcare Group Lp Method for manufacturing electrosurgical seal plates
US9024237B2 (en) * 2009-09-29 2015-05-05 Covidien Lp Material fusing apparatus, system and method of use
AU2010314930C1 (en) 2009-11-05 2014-04-03 Stratus Medical, LLC Methods and systems for spinal radio frequency neurotomy
CA2790328C (en) 2010-02-18 2017-04-18 University Of Virginia Patent Foundation System, method, and computer program product for simulating epicardial electrophysiology procedures
WO2011146243A1 (en) 2010-05-21 2011-11-24 Nimbus Concepts, Llc Systems and methods for tissue ablation
US9173698B2 (en) * 2010-09-17 2015-11-03 Aesculap Ag Electrosurgical tissue sealing augmented with a seal-enhancing composition
US9113940B2 (en) 2011-01-14 2015-08-25 Covidien Lp Trigger lockout and kickback mechanism for surgical instruments
US20120220813A1 (en) * 2011-01-25 2012-08-30 Sanford Lane Devices and methods for applying energy to a muscular layer
US9265568B2 (en) * 2011-05-16 2016-02-23 Coviden Lp Destruction of vessel walls for energy-based vessel sealing enhancement
US9072518B2 (en) * 2011-05-31 2015-07-07 Atricure, Inc. High-voltage pulse ablation systems and methods
USD680220S1 (en) 2012-01-12 2013-04-16 Coviden IP Slider handle for laparoscopic device
US9314290B2 (en) 2012-01-13 2016-04-19 Myoscience, Inc. Cryogenic needle with freeze zone regulation
US9241753B2 (en) 2012-01-13 2016-01-26 Myoscience, Inc. Skin protection for subdermal cryogenic remodeling for cosmetic and other treatments
EP2802278B1 (en) 2012-01-13 2016-12-07 Myoscience, Inc. Cryogenic probe filtration system
US9017318B2 (en) 2012-01-20 2015-04-28 Myoscience, Inc. Cryogenic probe system and method
US8939975B2 (en) 2012-07-17 2015-01-27 Covidien Lp Gap control via overmold teeth and hard stops
EP3603501A1 (en) 2012-08-09 2020-02-05 University of Iowa Research Foundation Catheter systems for surrounding a tissue structure
US9204921B2 (en) 2012-12-13 2015-12-08 Cook Medical Technologies Llc RF energy controller and method for electrosurgical medical devices
US9364277B2 (en) 2012-12-13 2016-06-14 Cook Medical Technologies Llc RF energy controller and method for electrosurgical medical devices
US9433464B2 (en) * 2013-03-14 2016-09-06 Biosense Webster (Israel) Ltd. Catheter with needles for ablating tissue layers in vessel
US9610112B2 (en) 2013-03-15 2017-04-04 Myoscience, Inc. Cryogenic enhancement of joint function, alleviation of joint stiffness and/or alleviation of pain associated with osteoarthritis
US10016229B2 (en) 2013-03-15 2018-07-10 Myoscience, Inc. Methods and systems for treatment of occipital neuralgia
CN105208954B (en) 2013-03-15 2019-06-04 肌肉科技股份有限公司 Low temperature Blunt dissection method and apparatus
US9295512B2 (en) 2013-03-15 2016-03-29 Myoscience, Inc. Methods and devices for pain management
US10646267B2 (en) 2013-08-07 2020-05-12 Covidien LLP Surgical forceps
EP3065658B1 (en) 2013-11-05 2021-03-31 Pacira CryoTech, Inc. Secure cryosurgical treatment system
WO2015103574A1 (en) 2014-01-06 2015-07-09 Iowa Approach Inc. Apparatus and methods for renal denervation ablation
EP4238521A3 (en) 2014-05-07 2023-11-29 Farapulse, Inc. Methods and apparatus for selective tissue ablation
WO2015192027A1 (en) 2014-06-12 2015-12-17 Iowa Approach Inc. Method and apparatus for rapid and selective transurethral tissue ablation
WO2015192018A1 (en) 2014-06-12 2015-12-17 Iowa Approach Inc. Method and apparatus for rapid and selective tissue ablation with cooling
US10231777B2 (en) 2014-08-26 2019-03-19 Covidien Lp Methods of manufacturing jaw members of an end-effector assembly for a surgical instrument
US10080606B2 (en) 2014-09-17 2018-09-25 Covidien Lp Method of forming a member of an end effector
EP3206613B1 (en) 2014-10-14 2019-07-03 Farapulse, Inc. Apparatus for rapid and safe pulmonary vein cardiac ablation
KR101658222B1 (en) * 2014-10-31 2016-09-20 인하대학교 산학협력단 Electrode array for nerve stimulation
WO2017031712A1 (en) 2015-08-26 2017-03-02 Covidien Lp Electrosurgical end effector assemblies and electrosurgical forceps configured to reduce thermal spread
US10213250B2 (en) 2015-11-05 2019-02-26 Covidien Lp Deployment and safety mechanisms for surgical instruments
US10130423B1 (en) 2017-07-06 2018-11-20 Farapulse, Inc. Systems, devices, and methods for focal ablation
US10660702B2 (en) 2016-01-05 2020-05-26 Farapulse, Inc. Systems, devices, and methods for focal ablation
US10172673B2 (en) 2016-01-05 2019-01-08 Farapulse, Inc. Systems devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
US20170189097A1 (en) 2016-01-05 2017-07-06 Iowa Approach Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
US11311327B2 (en) 2016-05-13 2022-04-26 Pacira Cryotech, Inc. Methods and systems for locating and treating nerves with cold therapy
WO2017218734A1 (en) 2016-06-16 2017-12-21 Iowa Approach, Inc. Systems, apparatuses, and methods for guide wire delivery
US9987081B1 (en) 2017-04-27 2018-06-05 Iowa Approach, Inc. Systems, devices, and methods for signal generation
US10617867B2 (en) 2017-04-28 2020-04-14 Farapulse, Inc. Systems, devices, and methods for delivery of pulsed electric field ablative energy to esophageal tissue
US11166759B2 (en) 2017-05-16 2021-11-09 Covidien Lp Surgical forceps
EP3681391A1 (en) 2017-09-12 2020-07-22 Farapulse, Inc. Systems, apparatuses, and methods for ventricular focal ablation
US11134998B2 (en) 2017-11-15 2021-10-05 Pacira Cryotech, Inc. Integrated cold therapy and electrical stimulation systems for locating and treating nerves and associated methods
JP2021522903A (en) 2018-05-07 2021-09-02 ファラパルス,インコーポレイテッド Systems, devices, and methods for delivering ablation energy to tissues
CN116327352A (en) 2018-05-07 2023-06-27 波士顿科学医学有限公司 Epicardial ablation catheter
WO2019217317A1 (en) 2018-05-07 2019-11-14 Farapulse, Inc. Systems, apparatuses, and methods for filtering high voltage noise induced by pulsed electric field ablation
JP2022501112A (en) 2018-09-20 2022-01-06 ファラパルス,インコーポレイテッド Systems, devices, and methods for the delivery of pulsed field ablation energy to endocardial tissue
US10625080B1 (en) 2019-09-17 2020-04-21 Farapulse, Inc. Systems, apparatuses, and methods for detecting ectopic electrocardiogram signals during pulsed electric field ablation
US11065047B2 (en) 2019-11-20 2021-07-20 Farapulse, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US11497541B2 (en) 2019-11-20 2022-11-15 Boston Scientific Scimed, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US10842572B1 (en) 2019-11-25 2020-11-24 Farapulse, Inc. Methods, systems, and apparatuses for tracking ablation devices and generating lesion lines
US11832916B2 (en) 2020-01-29 2023-12-05 Covidien Lp System and methods for identifying vessels within tissue

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5403311A (en) * 1993-03-29 1995-04-04 Boston Scientific Corporation Electro-coagulation and ablation and other electrotherapeutic treatments of body tissue
US5443463A (en) * 1992-05-01 1995-08-22 Vesta Medical, Inc. Coagulating forceps
US5823197A (en) * 1994-06-24 1998-10-20 Somnus Medical Technologies, Inc. Method for internal ablation of turbinates
US5879349A (en) * 1996-02-23 1999-03-09 Somnus Medical Technologies, Inc. Apparatus for treatment of air way obstructions
US6030384A (en) * 1998-05-01 2000-02-29 Nezhat; Camran Bipolar surgical instruments having focused electrical fields
US6077257A (en) * 1996-05-06 2000-06-20 Vidacare, Inc. Ablation of rectal and other internal body structures

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016886A (en) 1974-11-26 1977-04-12 The United States Of America As Represented By The United States Energy Research And Development Administration Method for localizing heating in tumor tissue
US5281218A (en) 1992-06-05 1994-01-25 Cardiac Pathways Corporation Catheter having needle electrode for radiofrequency ablation
US6129724A (en) 1993-10-14 2000-10-10 Ep Technologies, Inc. Systems and methods for forming elongated lesion patterns in body tissue using straight or curvilinear electrode elements
US5472441A (en) * 1993-11-08 1995-12-05 Zomed International Device for treating cancer and non-malignant tumors and methods
US5895417A (en) 1996-03-06 1999-04-20 Cardiac Pathways Corporation Deflectable loop design for a linear lesion ablation apparatus
GB2314274A (en) 1996-06-20 1997-12-24 Gyrus Medical Ltd Electrode construction for an electrosurgical instrument
US5827268A (en) 1996-10-30 1998-10-27 Hearten Medical, Inc. Device for the treatment of patent ductus arteriosus and method of using the device
US6071303A (en) 1996-12-08 2000-06-06 Hearten Medical, Inc. Device for the treatment of infarcted tissue and method of treating infarcted tissue
US6113596A (en) 1996-12-30 2000-09-05 Enable Medical Corporation Combination monopolar-bipolar electrosurgical instrument system, instrument and cable
US5928224A (en) 1997-01-24 1999-07-27 Hearten Medical, Inc. Device for the treatment of damaged heart valve leaflets and methods of using the device
US6152139A (en) 1997-01-24 2000-11-28 Heartenmedical, Inc. Device and method for preparing veins
US5989284A (en) 1997-02-18 1999-11-23 Hearten Medical, Inc. Method and device for soft tissue modification
US5941845A (en) 1997-08-05 1999-08-24 Irvine Biomedical, Inc. Catheter having multiple-needle electrode and methods thereof
US5792140A (en) * 1997-05-15 1998-08-11 Irvine Biomedical, Inc. Catheter having cooled multiple-needle electrode
US6106520A (en) 1997-09-30 2000-08-22 Hearten Medical, Inc. Endocardial device for producing reversible damage to heart tissue
US6212433B1 (en) 1998-07-28 2001-04-03 Radiotherapeutics Corporation Method for treating tumors near the surface of an organ
US6086586A (en) 1998-09-14 2000-07-11 Enable Medical Corporation Bipolar tissue grasping apparatus and tissue welding method
US6283935B1 (en) 1998-09-30 2001-09-04 Hearten Medical Ultrasonic device for providing reversible tissue damage to heart muscle
US5919200A (en) 1998-10-09 1999-07-06 Hearten Medical, Inc. Balloon catheter for abrading a patent foramen ovale and method of using the balloon catheter
US6152923A (en) 1999-04-28 2000-11-28 Sherwood Services Ag Multi-contact forceps and method of sealing, coagulating, cauterizing and/or cutting vessels and tissue
US6546935B2 (en) 2000-04-27 2003-04-15 Atricure, Inc. Method for transmural ablation
US7422586B2 (en) * 2001-02-28 2008-09-09 Angiodynamics, Inc. Tissue surface treatment apparatus and method
US6497704B2 (en) * 2001-04-04 2002-12-24 Moshe Ein-Gal Electrosurgical apparatus

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5443463A (en) * 1992-05-01 1995-08-22 Vesta Medical, Inc. Coagulating forceps
US5403311A (en) * 1993-03-29 1995-04-04 Boston Scientific Corporation Electro-coagulation and ablation and other electrotherapeutic treatments of body tissue
US5823197A (en) * 1994-06-24 1998-10-20 Somnus Medical Technologies, Inc. Method for internal ablation of turbinates
US5879349A (en) * 1996-02-23 1999-03-09 Somnus Medical Technologies, Inc. Apparatus for treatment of air way obstructions
US6077257A (en) * 1996-05-06 2000-06-20 Vidacare, Inc. Ablation of rectal and other internal body structures
US6030384A (en) * 1998-05-01 2000-02-29 Nezhat; Camran Bipolar surgical instruments having focused electrical fields

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9510899B2 (en) 2004-04-01 2016-12-06 The General Hospital Corporation Method and apparatus for dermatological treatment and tissue reshaping

Also Published As

Publication number Publication date
WO2002060523A2 (en) 2002-08-08
US20020120263A1 (en) 2002-08-29
AU2002248196A1 (en) 2002-08-12
WO2002060523A9 (en) 2002-11-28
EP1349510A2 (en) 2003-10-08
US6723092B2 (en) 2004-04-20
EP1349510A4 (en) 2005-07-13

Similar Documents

Publication Publication Date Title
WO2002060523A3 (en) Atrial fibrillation rf treatment device and method
US20240050145A1 (en) Ablation System, Clamp and Method of Use
US6030384A (en) Bipolar surgical instruments having focused electrical fields
JP4707676B2 (en) Electrosurgical equipment
US9283029B2 (en) Skin treatment using a multi-discharge applicator
US6165174A (en) Instrument for interrupting conduction paths within the heart
US20060074413A1 (en) Method and apparatus for substantial and uniform ablation about a linear bipolar array of electrodes
US6695838B2 (en) System and method for performing cardiac tissue ablation
US8500729B2 (en) Electrosurgical device with controllable electric field profile
ATE425702T1 (en) RADIO FREQUENCY GENERATOR FOR ABLATION DEVICE
JP5368434B2 (en) Catheter for percutaneous transcatheter ablation of cardiac arrhythmia using bipolar radio frequency
WO2006031289A3 (en) Multielectrode electrosurgical instrument
ATE332166T1 (en) EXTENDABLE INTRACARDIAL REFERENCE ELECTRODE AND METHODS OF USE
JPH1147148A (en) Ablation catheter with plurality of electrode
EP1850776A1 (en) Method and apparatus for controlling a surgical ablation device
JPH11501555A (en) Electrosurgical cutting and resection system and method
ATE333843T1 (en) MAPPING DEVICE
JP2006504453A (en) System and method for heating a body part of a patient's body
CA2279311A1 (en) Apparatus for biological tissue treatment utilizing high frequency
CN1250360A (en) Electric field concentrated electrosurgical electrode
CN110327112A (en) A kind of radio-frequency ablation clamp and the multielectrode recoding ablation system comprising radio-frequency ablation clamp
WO2009030714A1 (en) Coagulation stencil and application device
US11311330B2 (en) Portable device used especially for electrofulguration and electrodesiccation
US6269271B1 (en) Method and apparatus for skin brown spot removal
JPH0542166A (en) Electrode catherter for high-frequency abrasion

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: C2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: C2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

COP Corrected version of pamphlet

Free format text: PAGES 1/13-13/13, DRAWINGS, REPLACED BY NEW PAGES 1/12-12/12; DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2001997075

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2001997075

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP