WO2002061429A8 - A label-free high-throughput optical technique for detecting biomolecular interactions - Google Patents

A label-free high-throughput optical technique for detecting biomolecular interactions

Info

Publication number
WO2002061429A8
WO2002061429A8 PCT/US2001/045455 US0145455W WO02061429A8 WO 2002061429 A8 WO2002061429 A8 WO 2002061429A8 US 0145455 W US0145455 W US 0145455W WO 02061429 A8 WO02061429 A8 WO 02061429A8
Authority
WO
WIPO (PCT)
Prior art keywords
label
free high
optical technique
biomolecular interactions
throughput optical
Prior art date
Application number
PCT/US2001/045455
Other languages
French (fr)
Other versions
WO2002061429A2 (en
Inventor
Brian T Cunningham
Jane Pepper
Bo Lin
Peter Li
Homer Pien
Original Assignee
Sru Biosystems Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27399745&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2002061429(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sru Biosystems Llc filed Critical Sru Biosystems Llc
Priority to CA2427689A priority Critical patent/CA2427689C/en
Priority to JP2002561944A priority patent/JP4202140B2/en
Priority to AU2002249786A priority patent/AU2002249786B2/en
Priority to US10/399,940 priority patent/US7202076B2/en
Priority to EP01998024A priority patent/EP1337847A1/en
Publication of WO2002061429A2 publication Critical patent/WO2002061429A2/en
Publication of WO2002061429A8 publication Critical patent/WO2002061429A8/en
Priority to US11/290,036 priority patent/US7524625B2/en
Priority to US12/402,629 priority patent/US8293542B2/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251—Colorimeters; Construction thereof
    • G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4788—Diffraction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G01N21/7743—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure the reagent-coated grating coupling light in or out of the waveguide
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00—Optical elements other than lenses
    • G02B5/18—Diffraction gratings
    • G02B5/1809—Diffraction gratings with pitch less than or comparable to the wavelength
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
PCT/US2001/045455 2000-10-30 2001-10-23 A label-free high-throughput optical technique for detecting biomolecular interactions WO2002061429A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CA2427689A CA2427689C (en) 2000-10-30 2001-10-23 A label-free high-throughput optical technique for detecting biomolecular interactions
JP2002561944A JP4202140B2 (en) 2000-10-30 2001-10-23 Label-free high-throughput optical technique for detection of biomolecular interactions
AU2002249786A AU2002249786B2 (en) 2000-10-30 2001-10-23 A label-free high-throughput optical technique for detecting biomolecular interactions
US10/399,940 US7202076B2 (en) 2000-10-30 2001-10-23 Label-free high-throughput optical technique for detecting biomolecular interactions
EP01998024A EP1337847A1 (en) 2000-10-30 2001-10-23 A label-free high-throughput optical technique for detecting biomolecular interactions
US11/290,036 US7524625B2 (en) 2000-10-30 2005-11-30 Real time binding analysis of antigens on a biosensor surface
US12/402,629 US8293542B2 (en) 2000-10-30 2009-03-12 Real time binding analysis of antigens on a biosensor surface

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US24431200P 2000-10-30 2000-10-30
US60/244,312 2000-10-30
US28331401P 2001-04-12 2001-04-12
US60/283,314 2001-04-12
US30302801P 2001-07-03 2001-07-03
US60/303,028 2001-07-03

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
US09/930,352 Continuation-In-Part US7094595B2 (en) 2000-10-30 2001-08-15 Label-free high-throughput optical technique for detecting biomolecular interactions
US11/290,036 Continuation-In-Part US7524625B2 (en) 2000-10-30 2005-11-30 Real time binding analysis of antigens on a biosensor surface

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/399,940 Continuation US7202076B2 (en) 2000-10-30 2001-10-23 Label-free high-throughput optical technique for detecting biomolecular interactions

Publications (2)

Publication Number Publication Date
WO2002061429A2 WO2002061429A2 (en) 2002-08-08
WO2002061429A8 true WO2002061429A8 (en) 2003-05-15

Family

ID=27399745

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2001/050723 WO2002059602A2 (en) 2000-10-30 2001-10-23 A label-free high-throughput optical technique for detecting biomolecular interactions
PCT/US2001/045455 WO2002061429A2 (en) 2000-10-30 2001-10-23 A label-free high-throughput optical technique for detecting biomolecular interactions

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2001/050723 WO2002059602A2 (en) 2000-10-30 2001-10-23 A label-free high-throughput optical technique for detecting biomolecular interactions

Country Status (6)

Country Link
US (6) US7118710B2 (en)
EP (2) EP1337847A1 (en)
JP (3) JP4202140B2 (en)
AU (2) AU2002246885A1 (en)
CA (1) CA2427689C (en)
WO (2) WO2002059602A2 (en)

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US9134307B2 (en) 2007-07-11 2015-09-15 X-Body, Inc. Method for determining ion channel modulating properties of a test reagent

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