WO2002064162A3 - Vaccine for transcutaneous immunization - Google Patents
Vaccine for transcutaneous immunization Download PDFInfo
- Publication number
- WO2002064162A3 WO2002064162A3 PCT/US2002/004254 US0204254W WO02064162A3 WO 2002064162 A3 WO2002064162 A3 WO 2002064162A3 US 0204254 W US0204254 W US 0204254W WO 02064162 A3 WO02064162 A3 WO 02064162A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- etec
- transcutaneous immunization
- vaccine
- toxoids
- colonization
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0258—Escherichia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02718962A EP1372708B1 (en) | 2001-02-13 | 2002-02-13 | Vaccine for transcutaneous immunization against travellers' diarrhoea |
DE60227157T DE60227157D1 (en) | 2001-02-13 | 2002-02-13 | IMPREGENTS FOR TRANSCUTANEOUS IMMUNIZATION AGAINST TRAVEL DIARRHOUS |
AU2002250071A AU2002250071B2 (en) | 2001-02-13 | 2002-02-13 | Vaccine for transcutaneous immunization |
CA2437899A CA2437899C (en) | 2001-02-13 | 2002-02-13 | Vaccine for transcutaneous immunization against etec-caused traveler's diarrhea |
DK02718962T DK1372708T3 (en) | 2001-02-13 | 2002-02-13 | Vaccine for transcutaneous immunization against travel animals |
JP2002563955A JP2005504002A (en) | 2001-02-13 | 2002-02-13 | Vaccine for transcutaneous immunization |
US10/467,887 US7527802B2 (en) | 2001-02-13 | 2002-02-13 | Vaccine for transcutaneous immunization |
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26801601P | 2001-02-13 | 2001-02-13 | |
US60/268,016 | 2001-02-13 | ||
US30411001P | 2001-07-11 | 2001-07-11 | |
US60/304,110 | 2001-07-11 | ||
US31048301P | 2001-08-08 | 2001-08-08 | |
US31044701P | 2001-08-08 | 2001-08-08 | |
US60/310,447 | 2001-08-08 | ||
US60/310,483 | 2001-08-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002064162A2 WO2002064162A2 (en) | 2002-08-22 |
WO2002064162A3 true WO2002064162A3 (en) | 2003-10-30 |
Family
ID=27500924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/004254 WO2002064162A2 (en) | 2001-02-13 | 2002-02-13 | Vaccine for transcutaneous immunization |
Country Status (12)
Country | Link |
---|---|
US (1) | US7527802B2 (en) |
EP (1) | EP1372708B1 (en) |
JP (2) | JP2005504002A (en) |
AT (1) | ATE398461T1 (en) |
AU (1) | AU2002250071B2 (en) |
CA (1) | CA2437899C (en) |
CY (1) | CY1111030T1 (en) |
DE (1) | DE60227157D1 (en) |
DK (1) | DK1372708T3 (en) |
ES (1) | ES2310201T3 (en) |
PT (1) | PT1372708E (en) |
WO (1) | WO2002064162A2 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8911742B2 (en) | 1996-11-14 | 2014-12-16 | The United States Of America As Represented By The Secretary Of The Army | Transcutaneous immunization without heterologous adjuvant |
US9220681B2 (en) | 2012-07-05 | 2015-12-29 | Sigmoid Pharma Limited | Formulations |
US9278070B2 (en) | 2009-05-18 | 2016-03-08 | Sigmoid Pharma Limited | Composition comprising oil drops |
Families Citing this family (54)
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ES2310201T3 (en) * | 2001-02-13 | 2009-01-01 | Government Of The United States Of America, As Represented By The Secretary Of The Army | VACCINE FOR TRANSCUTANEOUS IMMUNIZATION AGAINST TRAVELERS 'DIARRHEA. |
US20040109869A1 (en) * | 2001-03-19 | 2004-06-10 | Iomai Corporation | Transcutaneous immunostimulation |
EP1481053B1 (en) * | 2002-02-25 | 2007-09-12 | US Army Medical Research & Materiel Command | Method of making cs6 antigen vaccine for treating, preventing, or inhibiting enterotoxigenic escherichia coli infections |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
TWI350174B (en) * | 2003-03-12 | 2011-10-11 | Wyeth Corp | Adjuvanted bovine vaccines |
EP1543836A1 (en) * | 2003-12-17 | 2005-06-22 | Berna Biotech AG | Recombinant Vibrio cholerae strain and vaccine comprising said strain |
WO2005113005A2 (en) * | 2004-05-20 | 2005-12-01 | The United States Of America As Represented By The Secretary Of The Army | Transcutaneous and/or transdermal transport of materials |
US20090017056A1 (en) * | 2004-06-15 | 2009-01-15 | Iomai Corporation | Skin immunization using lt-sta fusion proteins |
EP1784211A4 (en) | 2004-07-29 | 2010-06-30 | Novartis Vaccines & Diagnostic | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae |
WO2006039659A1 (en) * | 2004-10-02 | 2006-04-13 | Sri International | Bioadhesive delivery system for transmucosal delivery of beneficial agents |
ES2610395T3 (en) | 2005-01-11 | 2017-04-27 | The United States Of America As Represented By The Secretary Of The Navy | Adhesins supplemented by donor chain as immunogen against Escherichia coli |
FR2887457B1 (en) * | 2005-06-23 | 2007-10-05 | Fond Bettencourt Schueller | TRANSCUTANE TARGETING VACCINATION |
US7527801B2 (en) | 2005-11-22 | 2009-05-05 | Novartis Vaccines And Diagnostics, Inc. | Norovirus and Sapovirus antigens |
WO2007117339A2 (en) | 2006-01-11 | 2007-10-18 | The United States Of America As Respresented By The Secretary Of The Navy | Adhesin-enterotoxin chimera based immunogenic composition against entertoxigenic escherichia coli |
EP1981536A4 (en) * | 2006-02-01 | 2012-03-14 | Gotovax Ab | Colonization factor (cf) antigens of enterotoxigenic escherichia coli in recombinant bacteria |
WO2009034473A2 (en) | 2007-09-12 | 2009-03-19 | Novartis Ag | Gas57 mutant antigens and gas57 antibodies |
FR2924349B1 (en) | 2007-12-03 | 2010-01-01 | Dbv Tech | ALLERGEN DISENSIBILITY METHOD |
FR2924350B1 (en) * | 2007-12-03 | 2010-08-13 | Dbv Tech | METHOD AND COMPOSITIONS FOR SKIN VACCINATION |
GB0818453D0 (en) | 2008-10-08 | 2008-11-12 | Novartis Ag | Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom |
RU2498994C2 (en) | 2007-12-21 | 2013-11-20 | Новартис Аг | Mutant shapes of o-streptolysin |
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US7927586B2 (en) * | 2008-07-08 | 2011-04-19 | South Dakota State University | Vaccine for porcine post-weaning diarrhea caused by enterotoxigenic Escherichia coli |
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CN103897045A (en) | 2009-01-12 | 2014-07-02 | 诺华股份有限公司 | Cna_b domain antigens in vaccines against gram positive bacteria |
EP3549602A1 (en) | 2009-03-06 | 2019-10-09 | GlaxoSmithKline Biologicals S.A. | Chlamydia antigens |
US20100286600A1 (en) * | 2009-05-08 | 2010-11-11 | Bommannan D Bommi | Transdermal patch device |
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EP2442826B1 (en) | 2009-06-15 | 2015-07-08 | National University of Singapore | Influenza vaccine, composition, and methods of use |
CN107582526A (en) | 2009-08-12 | 2018-01-16 | 希格默伊德药业有限公司 | Immune regulation composite comprising polymer substrate and oil phase |
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AU2011276328C1 (en) | 2010-07-06 | 2016-01-21 | Novartis Ag | Norovirus derived immunogenic compositions and methods |
US20130189303A1 (en) | 2011-08-02 | 2013-07-25 | Yan Zhou | Recombinant swine influenza virus and uses thereof |
DK2750701T3 (en) | 2011-09-12 | 2016-01-11 | Scandinavian Biopharma Holding Ab | PROCEDURE FOR INCREASING ETEC-CS6 ANTIGEN PRESENTATION ON CELL SURFACE AND THEREFORE AVAILABLE PRODUCTS |
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DK3106176T3 (en) | 2011-12-06 | 2018-01-08 | Valneva Austria Gmbh | ALUMINUM COMPOUNDS FOR USE IN THERAPEUTICS AND VACCINES |
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CA2904388C (en) * | 2013-03-08 | 2023-09-26 | Research Institute At Nationwide Children's Hospital | Transcutaneous dosage formulation |
GB201319791D0 (en) | 2013-11-08 | 2013-12-25 | Sigmoid Pharma Ltd | Formulations |
US9649279B2 (en) | 2013-12-16 | 2017-05-16 | Massachusetts Institute Of Technology | Fortified micronutrient salt formulations |
JP2017507165A (en) * | 2013-12-16 | 2017-03-16 | マサチューセッツ インスティテュート オブ テクノロジー | Micromolded or three-dimensional printed pulsed release vaccine formulation |
SI3215127T1 (en) | 2014-11-07 | 2021-03-31 | Sublimity Therapeutics Limited DCU Alpha Innovation Campus | Compositions comprising cyclosporin |
US20180243392A1 (en) * | 2015-03-17 | 2018-08-30 | Vanderbilt University | Cs21 and lnga protein vaccines |
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US11324816B2 (en) | 2015-08-31 | 2022-05-10 | Technovax, Inc. | Human respiratory syncytial virus (HRSV) virus-like particles (VLPS) based vaccine |
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WO1998020734A1 (en) * | 1996-11-14 | 1998-05-22 | The Government Of The United States Of America, As Represented By The Secretary Of The Army | Adjuvant for transcutaneous immunization |
US5914114A (en) * | 1995-06-02 | 1999-06-22 | The United States Of America As Represented By The Secretary Of The Army | Method of raising antibodies against E. coli of the family CS4-CFA/I |
WO1999043350A1 (en) * | 1998-02-25 | 1999-09-02 | Iomai Corporation | Use of skin penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response induced by adp-ribosylating exotoxin |
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- 2002-02-13 PT PT02718962T patent/PT1372708E/en unknown
- 2002-02-13 CA CA2437899A patent/CA2437899C/en not_active Expired - Fee Related
- 2002-02-13 EP EP02718962A patent/EP1372708B1/en not_active Expired - Lifetime
- 2002-02-13 AU AU2002250071A patent/AU2002250071B2/en not_active Ceased
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US8911742B2 (en) | 1996-11-14 | 2014-12-16 | The United States Of America As Represented By The Secretary Of The Army | Transcutaneous immunization without heterologous adjuvant |
US9278070B2 (en) | 2009-05-18 | 2016-03-08 | Sigmoid Pharma Limited | Composition comprising oil drops |
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WO2002064162A2 (en) | 2002-08-22 |
PT1372708E (en) | 2008-09-29 |
DE60227157D1 (en) | 2008-07-31 |
DK1372708T3 (en) | 2008-10-20 |
CY1111030T1 (en) | 2015-06-11 |
AU2002250071B2 (en) | 2008-02-14 |
ES2310201T3 (en) | 2009-01-01 |
EP1372708B1 (en) | 2008-06-18 |
EP1372708A2 (en) | 2004-01-02 |
ATE398461T1 (en) | 2008-07-15 |
US20040146534A1 (en) | 2004-07-29 |
JP2005504002A (en) | 2005-02-10 |
CA2437899C (en) | 2012-05-15 |
CA2437899A1 (en) | 2002-08-22 |
JP2010180228A (en) | 2010-08-19 |
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