WO2002065941A3 - Method of controlling body temperature - Google Patents

Method of controlling body temperature Download PDF

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Publication number
WO2002065941A3
WO2002065941A3 PCT/US2002/004292 US0204292W WO02065941A3 WO 2002065941 A3 WO2002065941 A3 WO 2002065941A3 US 0204292 W US0204292 W US 0204292W WO 02065941 A3 WO02065941 A3 WO 02065941A3
Authority
WO
WIPO (PCT)
Prior art keywords
patient
heat exchange
temperature
balloon
uptake inhibitor
Prior art date
Application number
PCT/US2002/004292
Other languages
French (fr)
Other versions
WO2002065941A2 (en
Inventor
Michael W Dae
Timothy R Machold
Wade A Keller
Original Assignee
Radiant Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Radiant Medical Inc filed Critical Radiant Medical Inc
Priority to AU2002255543A priority Critical patent/AU2002255543A1/en
Publication of WO2002065941A2 publication Critical patent/WO2002065941A2/en
Publication of WO2002065941A3 publication Critical patent/WO2002065941A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A61F7/123—Devices for heating or cooling internal body cavities using a flexible balloon containing the thermal element
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0095—Heating or cooling appliances for medical or therapeutic treatment of the human body with a temperature indicator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels

Abstract

A method and apparatus of lowering the body temperature of a patient while reducing shivering by using a heat exchange device (4) in combination with an α2-adrenoreceptor agonist, a non-opiod analgesic monoamine uptake inhibitor or neuropeptide that temporarily reduces shivering. The devices disclosed include a catheter (10) having a heat exchange balloon (12) thereon with heat exchange fluid circulating through the interior of the balloon. The heat exchange balloon is placed in the vasculature (16) of a patient, and the heat exchange fluid at a temperature other than the temperature of the blood in the vasculature in circulated through the interior of the balloon to add or remove heat from the blood of the patient. Various α2-adrenoreceptor agonists, non-opiod analgesic monamine uptake inhibitor or neuropeptides are disclosed including dexmedetomidine, nepofam and neurotensin and pharmaceutically acceptable salts thereof. A control system for the control of the patient's temperature is disclosed for controlling the patient's temperature in conjunction with administering the α2-adrenoreceptor agonist, non-opiod analgesic monoamine uptake inhibitor or neuropeptide.
PCT/US2002/004292 2001-02-15 2002-02-14 Method of controlling body temperature WO2002065941A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002255543A AU2002255543A1 (en) 2001-02-15 2002-02-14 Method of controlling body temperature

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/784,930 US6582457B2 (en) 2001-02-15 2001-02-15 Method of controlling body temperature while reducing shivering
US09/784,930 2001-02-15

Publications (2)

Publication Number Publication Date
WO2002065941A2 WO2002065941A2 (en) 2002-08-29
WO2002065941A3 true WO2002065941A3 (en) 2003-04-17

Family

ID=25133970

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/004292 WO2002065941A2 (en) 2001-02-15 2002-02-14 Method of controlling body temperature

Country Status (3)

Country Link
US (1) US6582457B2 (en)
AU (1) AU2002255543A1 (en)
WO (1) WO2002065941A2 (en)

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US6685732B2 (en) 1998-03-31 2004-02-03 Innercool Therapies, Inc. Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing microporous balloon
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Also Published As

Publication number Publication date
AU2002255543A1 (en) 2002-09-04
WO2002065941A2 (en) 2002-08-29
US20020111657A1 (en) 2002-08-15
US6582457B2 (en) 2003-06-24

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