WO2002077774A3 - Electrophysiologic measure of endpoints for ablation lesions created in fibrillating substrates - Google Patents

Electrophysiologic measure of endpoints for ablation lesions created in fibrillating substrates Download PDF

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Publication number
WO2002077774A3
WO2002077774A3 PCT/US2002/009388 US0209388W WO02077774A3 WO 2002077774 A3 WO2002077774 A3 WO 2002077774A3 US 0209388 W US0209388 W US 0209388W WO 02077774 A3 WO02077774 A3 WO 02077774A3
Authority
WO
WIPO (PCT)
Prior art keywords
measure
lesion
methods
electrophysiologic
fibrillating
Prior art date
Application number
PCT/US2002/009388
Other languages
French (fr)
Other versions
WO2002077774A2 (en
Inventor
Javier E Sanchez
Michael E Benser
Raymond E Ideker
William M Smith
Original Assignee
Uab Research Foundation
Javier E Sanchez
Hall Jeffrey A
Michael E Benser
Raymond E Ideker
William M Smith
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uab Research Foundation, Javier E Sanchez, Hall Jeffrey A, Michael E Benser, Raymond E Ideker, William M Smith filed Critical Uab Research Foundation
Priority to AU2002306891A priority Critical patent/AU2002306891A1/en
Publication of WO2002077774A2 publication Critical patent/WO2002077774A2/en
Publication of WO2002077774A3 publication Critical patent/WO2002077774A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25Bioelectric electrodes therefor
    • A61B5/279Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/28Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
    • A61B5/283Invasive
    • A61B5/287Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00839Bioelectrical parameters, e.g. ECG, EEG
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04Arrangements of multiple sensors of the same type
    • A61B2562/043Arrangements of multiple sensors of the same type in a linear array

Abstract

Methods, systems, and computer program products measure electrical activity of the cardiac tissue (48) proximate the lesion site during the ablation treatment, and then compare the measurements to determine whether the lesion is clinically efficacious so as to be able to block myocardial propagation. The methods can include obtaining the measurements and performing the ablation therapy while the subject is experiencing atrial fibrillation and may measure the standard deviation (127) of the electrogram signal. Certain of the methods and systems measure (210) the electrical activity at multiple sites about the lesion site to detect whether the lesion is uniformly of sufficiently transmural about its length.
PCT/US2002/009388 2001-03-27 2002-03-25 Electrophysiologic measure of endpoints for ablation lesions created in fibrillating substrates WO2002077774A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002306891A AU2002306891A1 (en) 2001-03-27 2002-03-25 Electrophysiologic measure of endpoints for ablation lesions created in fibrillating substrates

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/818,206 US6743225B2 (en) 2001-03-27 2001-03-27 Electrophysiologic measure of endpoints for ablation lesions created in fibrillating substrates
US09/818,206 2001-03-27

Publications (2)

Publication Number Publication Date
WO2002077774A2 WO2002077774A2 (en) 2002-10-03
WO2002077774A3 true WO2002077774A3 (en) 2003-04-17

Family

ID=25224953

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/009388 WO2002077774A2 (en) 2001-03-27 2002-03-25 Electrophysiologic measure of endpoints for ablation lesions created in fibrillating substrates

Country Status (3)

Country Link
US (1) US6743225B2 (en)
AU (1) AU2002306891A1 (en)
WO (1) WO2002077774A2 (en)

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