WO2002079492A8 - Methods of diagnosis of angiogenesis, compositions and methods of screening for angiogenesis modulators - Google Patents
Methods of diagnosis of angiogenesis, compositions and methods of screening for angiogenesis modulatorsInfo
- Publication number
- WO2002079492A8 WO2002079492A8 PCT/US2002/004915 US0204915W WO02079492A8 WO 2002079492 A8 WO2002079492 A8 WO 2002079492A8 US 0204915 W US0204915 W US 0204915W WO 02079492 A8 WO02079492 A8 WO 02079492A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- angiogenesis
- diagnosis
- screening
- compositions
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002438030A CA2438030A1 (en) | 2001-02-14 | 2002-02-14 | Methods of diagnosis of angiogenesis, compositions and methods of screening for angiogenesis modulators |
EP02726581A EP1418943A1 (en) | 2001-02-14 | 2002-02-14 | Methods of diagnosis of angiogenesis, compositions and methods of screening for angiogenesis modulators |
AU2002257004A AU2002257004A1 (en) | 2001-02-14 | 2002-02-14 | Methods of diagnosis of angiogenesis, compositions and methods of screening for angiogenesis modulators |
JP2002578493A JP2004531249A (en) | 2001-02-14 | 2002-02-14 | Method for diagnosing angiogenesis, composition, and method for screening angiogenesis modulator |
Applications Claiming Priority (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78435601A | 2001-02-14 | 2001-02-14 | |
US09/784,356 | 2001-02-14 | ||
US79139001A | 2001-02-22 | 2001-02-22 | |
US09/791,390 | 2001-02-22 | ||
US28547501P | 2001-04-19 | 2001-04-19 | |
US60/285,475 | 2001-04-19 | ||
US31002501P | 2001-08-03 | 2001-08-03 | |
US60/310,025 | 2001-08-03 | ||
US35066601P | 2001-11-13 | 2001-11-13 | |
US60/350,666 | 2001-11-13 | ||
US33424401P | 2001-11-29 | 2001-11-29 | |
US60/334,244 | 2001-11-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002079492A2 WO2002079492A2 (en) | 2002-10-10 |
WO2002079492A8 true WO2002079492A8 (en) | 2004-03-25 |
Family
ID=27559580
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/004915 WO2002079492A2 (en) | 2001-02-14 | 2002-02-14 | Methods of diagnosis of angiogenesis, compositions and methods of screening for angiogenesis modulators |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1418943A1 (en) |
JP (1) | JP2004531249A (en) |
AU (1) | AU2002257004A1 (en) |
CA (1) | CA2438030A1 (en) |
WO (1) | WO2002079492A2 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8927700B2 (en) | 2009-08-21 | 2015-01-06 | Gilead Biologics, Inc. | Catalytic domains from lysyl oxidase and LOXL2 |
US9107935B2 (en) | 2009-01-06 | 2015-08-18 | Gilead Biologics, Inc. | Chemotherapeutic methods and compositions |
US9176139B2 (en) | 2007-08-02 | 2015-11-03 | Gilead Biologics, Inc. | LOX and LOXL2 inhibitors and uses thereof |
US9182405B2 (en) | 2006-04-04 | 2015-11-10 | Singulex, Inc. | Highly sensitive system and method for analysis of troponin |
US9494598B2 (en) | 2006-04-04 | 2016-11-15 | Singulex, Inc. | Highly sensitive system and method for analysis of troponin |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030114410A1 (en) | 2000-08-08 | 2003-06-19 | Technion Research And Development Foundation Ltd. | Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis |
AU2002249787A1 (en) | 2000-10-25 | 2002-08-19 | Diadexus, Inc. | Compositions and methods relating to lung specific genes and proteins |
US7622443B2 (en) | 2002-04-26 | 2009-11-24 | California Institute Of Technology | Method for inhibiting pro-angiogenic activities of endothelial cells selectively at a site of neoangiogenesis in a mammal by administration of the extracellular domain of D1-1 polypeptides |
AU2003234274A1 (en) | 2002-04-26 | 2003-11-10 | California Institute Of Technology | D1-1 nucleic acids, polypeptides and related methods |
AU2003268494A1 (en) * | 2002-09-11 | 2004-04-30 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
US7285268B2 (en) | 2002-11-26 | 2007-10-23 | Pdl Biopharma, Inc. | Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis |
US7276589B2 (en) | 2002-11-26 | 2007-10-02 | Pdl Biopharma, Inc. | Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis |
EP2233926A3 (en) | 2003-04-01 | 2011-01-12 | The Johns Hopkins University | Breast Endothelial Cell Expression Patterns |
US20060216286A1 (en) | 2003-04-25 | 2006-09-28 | Yasuaki Ito | Novel screening method |
US7267950B2 (en) * | 2003-05-01 | 2007-09-11 | Veridex, Lcc | Rapid extraction of RNA from cells and tissues |
US7833733B2 (en) | 2003-06-09 | 2010-11-16 | The University Of British Columbia | Methods for detecting and treating cancer |
US9309323B2 (en) | 2003-06-09 | 2016-04-12 | The University Of British Columbia | Methods for detecting and treating cancer |
JP2007527704A (en) * | 2003-06-30 | 2007-10-04 | ジェノバ・リミテッド | Secreted polypeptide species associated with cardiovascular disorders |
US7485297B2 (en) | 2003-08-12 | 2009-02-03 | Dyax Corp. | Method of inhibition of vascular development using an antibody |
DE10340373A1 (en) * | 2003-08-30 | 2005-03-24 | Henkel Kgaa | Determining the hair cycle in humans, by measuring protein or mRNA levels and classification as anagenic or catagenic, also for screening therapeutic or cosmetic agents that affect hair growth |
JP2005073621A (en) * | 2003-09-01 | 2005-03-24 | Japan Science & Technology Agency | Marker for cerebral tumor and method for diagnosing cerebral tumor |
WO2005069855A2 (en) | 2004-01-13 | 2005-08-04 | Rigel Pharmaceuticals, Inc. | Modulators of angiogenesis |
JP4857259B2 (en) | 2004-03-24 | 2012-01-18 | アボット バイオセラピューティクス コーポレイション | Use of anti-α5β1 antibodies to inhibit cancer cell growth |
EP1743944A4 (en) | 2004-04-23 | 2011-01-05 | Takeda Pharmaceutical | Novel method of screening |
WO2005113788A2 (en) * | 2004-05-21 | 2005-12-01 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g protein-coupled receptor kinase 6 (grk6) |
US8067189B2 (en) * | 2005-09-01 | 2011-11-29 | Bristol-Myers Squibb Company | Methods for determining sensitivity to vascular endothelial growth factor receptor-2 modulators by measuring the level of collagen type IV |
WO2007095353A2 (en) * | 2006-02-14 | 2007-08-23 | Geisinger Clinic | Gpcrs as angiogenesis targets |
US20090028793A1 (en) * | 2006-02-22 | 2009-01-29 | Philogen Spa | Vascular Tumor Markers |
ES2544957T3 (en) | 2006-03-21 | 2015-09-07 | Genentech, Inc. | Combined therapy involving alpha5beta1 antagonists |
SI2200700T1 (en) | 2007-09-26 | 2016-04-29 | Genentech, Inc. | Novel antibodies |
EP2216399A1 (en) | 2009-01-30 | 2010-08-11 | Université de la Méditerranée | Human soluble CD146, preparation and uses thereof |
NZ594343A (en) | 2009-03-25 | 2013-10-25 | Genentech Inc | Novel anti-alpha5beta1 antibodies and uses thereof |
JP5678045B2 (en) | 2009-06-08 | 2015-02-25 | シンギュレックス・インコーポレイテッド | High sensitivity biomarker panel |
CA2767442A1 (en) | 2009-07-08 | 2011-01-13 | Actgen Inc. | Antibody having anti-cancer activity |
WO2011027132A1 (en) | 2009-09-03 | 2011-03-10 | Cancer Research Technology Limited | Clec14a inhibitors |
-
2002
- 2002-02-14 AU AU2002257004A patent/AU2002257004A1/en not_active Abandoned
- 2002-02-14 EP EP02726581A patent/EP1418943A1/en not_active Ceased
- 2002-02-14 JP JP2002578493A patent/JP2004531249A/en active Pending
- 2002-02-14 WO PCT/US2002/004915 patent/WO2002079492A2/en not_active Application Discontinuation
- 2002-02-14 CA CA002438030A patent/CA2438030A1/en not_active Abandoned
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9182405B2 (en) | 2006-04-04 | 2015-11-10 | Singulex, Inc. | Highly sensitive system and method for analysis of troponin |
US9494598B2 (en) | 2006-04-04 | 2016-11-15 | Singulex, Inc. | Highly sensitive system and method for analysis of troponin |
US9176139B2 (en) | 2007-08-02 | 2015-11-03 | Gilead Biologics, Inc. | LOX and LOXL2 inhibitors and uses thereof |
US9107935B2 (en) | 2009-01-06 | 2015-08-18 | Gilead Biologics, Inc. | Chemotherapeutic methods and compositions |
US9289447B2 (en) | 2009-01-06 | 2016-03-22 | Gilead Biologics, Inc. | Chemotherapeutic methods and compositions |
US8927700B2 (en) | 2009-08-21 | 2015-01-06 | Gilead Biologics, Inc. | Catalytic domains from lysyl oxidase and LOXL2 |
Also Published As
Publication number | Publication date |
---|---|
EP1418943A1 (en) | 2004-05-19 |
CA2438030A1 (en) | 2002-10-10 |
AU2002257004A1 (en) | 2002-10-15 |
WO2002079492A2 (en) | 2002-10-10 |
JP2004531249A (en) | 2004-10-14 |
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