WO2002083926A3 - Methods of diagnosing and treating small intestinal bacterial overgrowth (sibo) and sibo-related conditions - Google Patents

Methods of diagnosing and treating small intestinal bacterial overgrowth (sibo) and sibo-related conditions Download PDF

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Publication number
WO2002083926A3
WO2002083926A3 PCT/US2002/012034 US0212034W WO02083926A3 WO 2002083926 A3 WO2002083926 A3 WO 2002083926A3 US 0212034 W US0212034 W US 0212034W WO 02083926 A3 WO02083926 A3 WO 02083926A3
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WIPO (PCT)
Prior art keywords
sibo
human subject
small intestinal
bacterial overgrowth
intestinal bacterial
Prior art date
Application number
PCT/US2002/012034
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French (fr)
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WO2002083926A2 (en
Inventor
Henry C Lin
Mark Pimentel
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Cedars Sinai Medical Center
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Publication date
Application filed by Cedars Sinai Medical Center filed Critical Cedars Sinai Medical Center
Priority to JP2002582263A priority Critical patent/JP4653936B2/en
Priority to CA2444548A priority patent/CA2444548C/en
Priority to AU2002256254A priority patent/AU2002256254B2/en
Priority to EP02725704.7A priority patent/EP1385476B1/en
Publication of WO2002083926A2 publication Critical patent/WO2002083926A2/en
Publication of WO2002083926A3 publication Critical patent/WO2002083926A3/en
Priority to AU2007201246A priority patent/AU2007201246B2/en

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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/18—Sulfur containing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/21—Hydrocarbon
    • Y10T436/214—Acyclic [e.g., methane, octane, isoparaffin, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/22—Hydrogen, per se

Abstract

Disclosed is a method of treating small intestinal bacterial overgrowth (SIBO) or a SIBO-caused condition in a human subject. SIBO-caused conditions include irritable bowel syndrome, fibromyalgia, chronic pelvic pain syndrome, chronic fatigue syndrome, depression, impaired mentation, impaired memory, halitosis, tinnitus, sugar craving, autism, attention deficit/hyperactivity disorder, drug sensitivity, an autoimmune disease, and Crohn's disease. Also disclosed are a method of screening for the abnormally likely presence of SIBO in a human subject and a method of detecting SIBO in a human subject. A method of determining the relative severity of SIBO or a SIBO-caused condition in a human subject, in whom small intestinal bacterial overgrowth (SIBO) has been detected, is also disclosed.
PCT/US2002/012034 2001-04-17 2002-04-16 Methods of diagnosing and treating small intestinal bacterial overgrowth (sibo) and sibo-related conditions WO2002083926A2 (en)

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JP2002582263A JP4653936B2 (en) 2001-04-17 2002-04-16 Methods for diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
CA2444548A CA2444548C (en) 2001-04-17 2002-04-16 Methods of diagnosing and treating small intestinal bacterial overgrowth (sibo) and sibo-related conditions
AU2002256254A AU2002256254B2 (en) 2001-04-17 2002-04-16 Methods of diagnosing and treating small intestinal bacterial overgrowth (sibo) and sibo-related conditions
EP02725704.7A EP1385476B1 (en) 2001-04-17 2002-04-16 Composition for treating small intestinal bacterial overgrowth (sibo) and sibo-related conditions
AU2007201246A AU2007201246B2 (en) 2001-04-17 2007-03-22 Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions

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US09/837,797 US7048906B2 (en) 1995-05-17 2001-04-17 Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions

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