WO2002085309A2 - Composition, formulations & kits for treatment of respiratory & lung disease with anti-sense oligonucleotides & a bronchodilating agent - Google Patents

Abstract

This patent relates to a composition comprising a carrier, oligonucleotides (oligos) that are anti-sense to adenosine receptors, and contain low amounts of or no adenosine (A), and bronchodilating agents. These agents and the composition and formulations provided are suitable for the treatment of respiratory tract, pulmonary and maliugnant diseases associated with bronchoconstriction, respiratory tract inflammation and allergies, impaired airways, including lung disease and diseases whose secondary effects afflict the lungs of a subject, such as allergies, asthma, impeded respiration, allergic rhinitis, pain, cystic fibrosis, pulmonary fibrosis, RDA, COPD, and cancers, among others. The present agents and composition may be administered preventatively, prophylactically or therapeutically in conjunction with other therapies, or may be utilized as a substitute for therapies that have significant, negative side effects.

Description

COMPOSITION. FORMULATIONS & KITS FOR TREATMENT OF RESPIRATORY & LUNG DISEASE WITH ANTI-SENSE OLIGONUCLEOTIDES & A BRONCHODE ATLNG AGENT

BACKGROUND OF THE INVENTION

Field of the Invention This patent relates to a composition comprising a carrier, oligonucleotides (oligos) that are anti-sense to adenosine receptors, and contain low amounts of or no adenosine (A), and bronchodilating agents. These agents and the composition and formulations provided are suitable for the treatment of respiratory tract, pulmonary and malignant diseases associated with bronchoconstriction, respiratory tract inflammation and allergies, impaired airways, including lung disease and diseases whose secondary effects afflict the lungs of a subject, such as allergies, asthma, impeded respiration, allergic rhinitis, pain, cystic fibrosis, pulmonary fibrosis, RDA, COPD, and cancers, among others. The present agents and composition may be adrninistered preventatively, prophylactically or therapeutically in conjunction with other therapies, or may be utilized as a substitute for therapies that have significant, negative side effects.

Background of the Invention Respiratory ailments, associated with a variety of conditions, are extremely common in the general population, and more so in certain ethnic groups, such as African Americans. In some cases they are accompanied by inflammation, wliich aggravates the condition of the lungs. Asthma, for example, is one of the most common diseases in industriahzed countries. In the United States it accounts for about 1% of all health care costs. An alarming increase in both the prevalence and mortality of asthma over the past decade has been reported, and asthma is predicted to be the preeminent occupational lung disease in the next decade. While the increasing mortality of asthma in industrialized countries could be attributable to the depletion reliance upon beta agonists in the treatment of this disease, the underlying causes of asthma remain poorly understood.

Diseases such as asthma, allergic rhinitis, and Acute Respiratory Distress Syndrome (ARDS), including RDS in pregnant mothers and in premature born infants, among others, are common diseases in industrialized countries, and in the United States alone, they account for extremely high health care costs. These diseases have recently been increasing at an alarming rate, both in terms of prevalence, morbidity and mortality. In spite of this, their underlying causes still remain poorly understood.

Asthma is a condition characterized by variable, in many instances reversible obstruction of the airways. This process is associated with lung inflammation and in some cases lung allergies. Many patients have acute episodes referred to as "asthma attacks," while others are afflicted with a chronic condition. The asthmatic process is believed to be triggered in some cases by inhalation of antigens by hypersensitive subjects. This condition is generally referred to as "extrinsic asthma." Other asthmatics have an intrinsic predisposition to the condition, which is thus referred to as "intrinsic asthma," and may be comprised of conditions of different origin, including those mediated by the adenosine receρtor(s), allergic conditions mediated by an immune IgE-mediated response, and others. All asthmas have a group of symptoms, which are characteristic of this condition: bronchoconstriction, lung inflammation and decreased lung surfactant. Existing bronchodilators and anti-inflammatories are currently commercially available and are prescribed for the treatment of asthma. The most common anti-inflarnmatories, corticosteroids, have considerable side effects but are commonly prescribed nevertheless. Most of the drugs available for the treatment of asthma are, more importantly, barely effective in a small number of patients. Acute Respiratory Distress Syndrome (ARDS), or stiff lung, shock lung, pump lung and congestive atelectasis, is believed to be caused by fluid accumulation within the lung which, in turn, causes the lung to stiffen. The condition is triggered within 48 hours by a variety of processes that injure the lungs such as trauma, head injury, shock, sepsis, multiple blood transfusions, medications, pulmonary embolism, severe pneumonia, smoke inhalation, rad' ttion, high altitude, near drowning, and others. In general, ARDS occurs as a medical emergency and may be caused by other conditions that directly or indirectly cause the blood vessels to "leak" fluid into tire lungs. In

ARDS, the ability of the lungs to expand is severely decreased and produces extensive damage to the air sacs and lining or endothelium of the lung. ARDS' most common symptoms are labored, rapid breathing, nasal flaring, cyanosis blue skin, lips and nails caused by lack of oxygen to the tissues, breathing difficulty, anxiety, stress, tension, joint stiffness, pain and temporarily absent breathing. ARDS is commonly diagnosed by testing for symptomatic signs, for example by a simple chest auscultation or examination with a stethoscope that may reveal abnormal symptomatic breath sounds. A preliminary diagnosis of ARDS may be confirmed with chest X-rays and the measurement of arterial blood gas. In some cases ARDS appears to be associated with other diseases, such as acute myelogenous leukemia, with acute tumor lysis syndrome (ATLS) developed after treatment with, e. g. cytosine arabinoside. In general, however, ARDS appears to be associated with traumatic injury, severe blood infections such as sepsis, or other systemic illness, high dose radiation therapy and chemotherapy, and inflammatory responses which lead to multiple organ failure, and in many cases death. In premature babies ("premies"), the lungs are not quite developed and, therefore, the fetus is in an anoxic state during development. Moreover, lung surfactant, a material critical for normal respiration, is generally not yet present in sufficient amounts at this early stage of life; however, premies often hyper-express the adenosine Ai receptor and/or underexpress the adenosine A_2a receptor and are, therefore, susceptible to respiratory problems including bronchoconstriction, lung inflammation and ARDS, among others. When Respiratory Distress Syndrome (RDS) occurs in premies, it is an extremely serious problem. Preterm infants exhibiting RDS are currently treated by ventilation and administration of oxygen and surfactant preparations. When premies survive RDS, they frequently develop bronchopulmonary dysplasia (BPD), also called chronic lung disease of early infancy, which is often fatal. The systemic acϊministration of adenosine was found useful for treating SVT, and as a pharmacologic means to evaluate cardiovascular health via an adenosine stress test commonly administered by hospitals and by doctors in private practice. Adenosine administered by inhalation, however, is known to cause bronchoconstriction in asthmatics, possibly due to mast cell degranulation and histamine release, effects which have not been observed in normal subjects. Adenosine infusion has caused respiratory compromise, for example, in patients with COPD. As a consequence of the untoward side effects observed in many patients, caution is recommended in the prescription of adenosine to patients with a variety of conditions, including obstructive lung disease, emphysema, bronchitis, etc, and complete avoidance of its administration to patients with or prone to bronchoconstriction or bronchospasm, such as asthma. In addition, the administration of adenosine must be discontinued in any patient who develops severe respiratory difficulties. It would be of great help if a formulation were to be made available for joint use when adenosine administration is required.

Allergic rhinitis afflicts one in five Americans, accounting for an estimated $4 to 10 billion in health care costs each year, and occurs at all ages. Because many people mislabel their symptoms as persistent colds or sinus problems, allergic rhinitis is probably underdiagnosed. Typically, IgE combines with allergens in the nose to produce chemical mediators, induction of cellular processes, and neurogenic stimulation, causing an underlying inflammation. Symptoms include nasal congestion, discharge, sneezing, and itching, as well as itchy, watery, swollen eyes. Over time, allergic rhinitis sufferers often develop sinusitis, otitis media with effusion, and nasal polyposis, and may exacerbate asthma, and is associated with mood and cognitive disturbances, fatigue and irritability. Degranulation of mast cells results in the release of preformed mediators that interact with various cells, blood vessels, and mucous glands to produce the typical rhinitis symptoms. Most early- and late-phase reactions occur in the nose after allergen exposure. The late-phase reaction is seen in chronic allergic rhinitis, with hypersecretion and congestion as the most prominent symptoms. Repeated exposure causes a hypersensitivity reaction to one or many allergens. Sufferers may also become hyperreactive to nonspecific triggers such as cold air or strong odors. Nonallergic rhinitis may be induced by infections, such as viruses, or associated with nasal polyps, as occurs in patients with aspirin idiosyncrasy. In addition, pregnancy, hypothyroidism, and exposure to occupational factors or medications can cause rhinitis, as well. NARES syndrome, a non-allergic type of rhinitis associated with eosinophils in the nasal secretions, typically occurs in middle-aged individuals and is accompanied by loss of smell. Saline is often recommended to improve nasal stuffiness, sneezing, and congestion, and saline sprays usually relieve mucosal irritation or dryness associated with various nasal conditions, minimize mucosal atrophy, and dislodge encrusted or thickened mucus, while causing no side effects, and may be tried first in pregnant patients. Also, if used immediately before intranasal corticosteroid dosing, saline helps prevent local irritation.

Anti-histamines often serve as a primary therapy. Terfenadine and astemizole, two non-sedating anti-histarnines, however, have been associated with a ventricular arrhythmia known as Torsades de Points, usually in interaction with other medications such as ketoconazole and erythromycin, or secondary to an underlying cardiac problem. To date loratadine, another nonsedating anti-histamine, and cetirizine have not been associated with serious adverse cardiovascular events, the most common side effect of cetirizine being drowsiness. Claritin, for example, may be effective in relieving sneezing, runny nose, and nasal, ocular and palatal itching in a low percentage of patients, although not approved for this indication or asthma. Aiiti-hista ines are typically combined with a decongestant to help relieve nasal congestion. Sympathomimetic medications are used as vasoconstrictors and decongestants, the three most common decongestants being pseudoephedrine, phenylpropanolamine and phenylephrine. These agents, however, cause hypertension, palpitations, tachycardia, restlessness, insomnia and headache. Topical decongestants are recommended for a limited period of time, as their overuse results in nasal dilatation. Anti-cholinergic agents, such as Cromolyn, have a role in patients with significant rhinorrhea or for specific entities such as "gustatory rhinitis", which is usually associated with ingestion of spicy foods, and have been used on the common cold. Sometimes the Cromolyn spray produces sneezing, transient headache, and even nasal burning. Topical and nasal spray corticosteroids such as Vancenase are effective agents in the treatment of rhinitis, especially for symptoms of congestion, sneezing, and runny nose, but often cause irritation, stinging, burning, sneezing, local bleeding and septal perforation. Topical steroids are generally more effective than Cromolyn Sodium, particularly in the treatment of NARES, but side effects limit their usefulness except for temporary therapy in patients with severe symptoms. Immunotherapy, while expensive and inconvenient, often can provide substantial benefits, especially the use of drugs that produce blocking antibodies, alter cellular histamine release, and result in decreased IgE. Presently available treatments, such as propranolol, verapamil, and adenosine, may help to minimize symptoms. Verapa il is most commonly used but it has several shortcomings, since it causes or exacerbates systemic hypotension, congestive heart failure, bradyarrhythmias, and ventricular fibrillation. In addition, verapamil readily crosses the placenta and has been shown to cause fetal bradycardia, heart block, depression of contractility, and hypotension. Adenosine has several advantages over verapamil, including rapid onset, brevity of side effects, theoretical safety, and probable lack of placental transfer, but may not be administered to a variety of patients. Chronic obstructive pulmonary disease (COPD) is characterized by airflow obstruction that is generally caused by chronic bronchitis, emphysema, or both. Emphysema is characterized by abnormal permanent enlargement of the air spaces distal to the terminal bronchioles, accompanied by destruction of their walls and without obvious fibrosis. Chronic bronchitis is characterized by chronic cough, mucus production, or both, for at least three months for at least two successive years where other causes of chronic cough have been excluded. COPD characteristically affects middle aged and elderly people, and is one of the leading causes of morbidity and mortality worldwide. In the United States it affects about 14 million people and is the fourth leading cause of death. Both morbidity and mortality, however, are rising. The estimated prevalence of this disease in the United States has risen by 41% since 1982, and age adjusted death rates rose by 71% between 1966 and 1985. This contrasts with the decline over the same period in age-adjusted mortality from all causes (wliich fell by 22%), and from cardiovascular diseases (which fell by 45%). COPD, however, is preventable, since it is believed that its main cause is exposure to cigarette smoke. The disease is rare in lifetime non-smokers, in whom exposure to environmental tobacco smoke will explain at least some of the airways obstruction. Other proposed etiological factors include airway hyper- responsiveness or hypersensitivity, ambient air pollution, and allergy. The airflow obstruction in COPD is usually progressive in people who continue to smoke. This results in early disability and shortened survival time. Stopping smoking reverts the decline in lung function to values for non-smokers. Many patients will use medication chronically for the rest of their lives, with the need for increased doses and additional drugs during exacerbations. Amongst the currently available treatments for COPD, short term benefits, but not long term effects, were found on its progression, from administration of anti-cholinergic drugs, βl adrenergic agonists, and oral steroids. Neither anti- cholinergic drugs nor βl adrenergic agonists have an effect on all people with COPD; nor do the two agents combined. The adverse effects of theophyllines and the need for frequent monitoring limit their usefulness. There is no evidence that anti-cholinergic agents affect the decline in lung function, and mucolytics have been shown to reduce the frequency of exacerbations but with a possible deleterious effect on lung function. The long-term effects of βl adrenergic agonists, oral corticosteroids, and antibiotics have not yet been evaluated, and up to the present time no other drug has been shown to affect the progression of the disease or survival. Thus, there is very little currently available to alleviate symptoms of COPD, prevent exacerbations, preserve optimal lung function, and improve daily living activities an quality of life.

Pulmonary fibrosis, interstitial lung disease (ILD), or interstitial pulmonary fibrosis, include more than 130 chronic lung disorders that affect the lung by damaging lung tissue, and producing inflammation in the walls of the air sacs in the lung, scarring or fibrosis in the interstitium (or tissue between the air sacs), and stiffening of the lung, thus the name of the disease. Breathlessness during exercise may be one of the first symptoms of these diseases, and a dry cough may be present. Neither the symptoms nor X-rays are often sufficient to tell apart different types of pulmonary fibrosis. Some pulmonary fibrosis patients have known causes and some have unknown or idiopathic causes. The course of this disease is generally unpredictable. Its progression includes thickening and stiffening of the lung tissue, inflammation and difficult breathing. Some people may need oxygen therapy as part of their treatment.

Cancer is one of the most prevalent and feared diseases of our times. It generally results from the carcinogenic transformation of normal cells of different epitheha. Two of the most damaging characteristics of carcinomas and other types of malignancies are their uncontrolled growth and their ability to create metastases in distant sites of the host, particularly a human host. It is usually these distant metastases that may cause serious consequences to the host since frequently the primary carcinoma is removed by surgery. The treatment of cancer presently relies on surgery, irradiation therapy and systemic therapies such as chemotherapy, different irnmunity- boosting medicines and procedures, hyperthermia and systemic, radioactively labeled monoclonal antibody treatment, immunotoxins and chemotherapeutic drugs.

Adenosine may constitute an important mediator in the lung for various diseases, including bronchial asthma, COPD, CF, RDS, rhinitis, pulmonary fibrosis, and others. Its potential role was suggested by the finding that asthmatics respond favorably to aerosolized adenosine with marked bronchoconstriction whereas normal individuals do not. An asthmatic rabbit animal model, the dust mite allergic rabbit model for human asthma, responded in a similar fashion to aerosolized adenosine with marked bronchoconstriction whereas non-asthmatic rabbits showed no response. More recent work with this animal model suggested that adenosine-induced bronchoconstriction and bronchial hyperresponsiveness in asthma may be mediated primarily through the stimulation of adenosine receptors. Adenosine has also been shown to cause adverse effects, including death, when administered therapeutically for other diseases and conditions in subjects with previously undiagnosed hyper reactive airways.

Adenosine is a purine involved in intermediary metabolism, and may constitute an important natural mediator of many of diseases. Adenosine plays a unique role in the body as a regulator of cellular metabolism. It can raise the cellular level of AMP, ADP and ATP which are the energy intermediates of the cell. Adenosine can stimulate or down regulate the activity of adenylate cyclase and hence regulate cAMP levels. cAMP, in turn, plays a role in neurotransmitter release, cellular division and hormone release. Adenosine's major role appears to be to act as a protective injury autocoid. In any condition in which ischemia, low oxygen tension or trauma occurs adenosine appears to play a role. Defects in synthesis, release, action and or degradation of adenosine have been postulated to contribute to the over activity of the brain excitatory amino acid neurotransmitters, and hence various pathological states. Adenosine has also been implicated as a primary determinant underlying the symptoms of bronchial asthma and other respiratory diseases, the induction of bronchoconstriction and the contraction of airway smooth muscle. Moreover, adenosine causes bronchoconstriction in asthmatics but not in non-asthmatics. Other data suggest the possibility that adenosine receptors may also be involved in allergic and inflammatory responses by reducing the hyperactivity of the central dopaminergic system. It has been postulated that the modulation of signal transduction at the surface of inflammatory cells influences acute inflammation. Adenosine is said to inhibit the production of super-oxide by stimulated neutrophils. Recent evidence suggests that adenosine may also play a protective role in stroke, CNS trauma, epilepsy, ischemic heart disease, coronary by-pass, radiation exposure and inflammation. Overall, adenosine appears to regulate cellular metabolism through ATP, to act as a carrier for methionine, to decrease cellular oxygen demand and to protect cells from ischemic injury. Adenosine is a tissue hormone or inter- cellular messenger that is released when cells are subject to ischemia, hypoxia, cellular stress, and increased workload, and or when the demand for ATP exceeds its supply. Adenosine is a purine and its formation is directly linked to ATP catabolism. It appears to modulate an array of physiological processes including vascular tone, hormone action, neural function, platelet aggregation and lymphocyte differentiation. It also may play a role in DNA formation, ATP biosynthesis and general intermediary metabolism. It is suggested that it regulates the formation of cAMP in the brain and in a variety of peripheral tissues. Adenosine regulates cAMP formation through two receptors A_! and A₂. Via Ai receptors, adenosine reduces adenylate cyclase activity, while it stimulates adenylate cyclase at A₂ receptors. The adenosine Ai receptors are more sensitive to adenosine than the A₂ receptors. The CNS effects of adenosine are generally believed to be Ai-receptor mediated, where as the peripheral effects such as hypotension, bradycardia, are said to be A₂ receptor mediated. Anti-sense oligonucleotides have received considerable theoretical consideration as potential useful pharmacological agents in human disease. Their practical application in actual models of human disease, however, has been somewhat elusive. One important impediment to their effective application has been a difficulty in finding an appropriate route of administration to deliver them to their site of action. Many in vivo experiments were conducted by administering anti-sense oligonucleotides directly to specific regions of the brain. These applications, however, necessarily have limited clinical utility due to their invasive nature. Although anti-sense oligonucleotides have received considerable theoretical consideration for their potential use as pharmacological agents in human disease, finding practical and effective applications for these agents in actual models of human disease, however, have been few and far between, particularly because they had to be administered in large doses. Another important consideration in the pharmacologic application of these molecules is their route of administration. Many in vivo applications have involved the direct administration of anti-sense oligonucleotides to limited regions of the brain. Such applications, however, have limited clinical utility due to their invasive nature. The systemic adminisfration of anti-sense oligonucleotides as pharmacological agents has been found to have also significant problems, not the least of which being an inherent difficulty in targeting disease-involved tissues. That is, the necessary dilution of the anti- sense oligonucleotide in the circulatory system makes extremely difficult to attain a therapeutic dose at the target tissue by intravenous or oral adminisfration. The bioavailability of orally administered anti-sense oligonucleotides is very low, of the order of less than about 5%. Anti-sense oligonucleotides have been used in therapy by many, including the present inventor, who in his previous work successfully treated various diseases and conditions by direct administration of these agents to the lung. In many instances, other workers have had to face the difficulties associated with the delivery of DNA molecules to a desired target. Thus, the route of administration may be of extreme importance for treating generalized diseases and conditions as well as those that are localized. In contrast, up to the present time, the delivery of anti-sense agents to the lung has been relatively undeveloped. As described by the present inventor in more detail below, the lung is an excellent target for the direct administration of anti-sense oligonucleotides and provides a non-invasive and a tissue-specific route.

A handful of medicaments have been available for the treatment of respiratory diseases, although in general they all have limitations. Theophylline, an important drug in the treatment of asthma, is a known adenosine receptor antagonist that was reported to eliminate adenosine-mediated bronchoconstriction in asthmatic rabbits. A selective adenosine Ai receptor antagonist, 8-cyclopentyl-l, 3-dipropylxanthine (DPCPX) was also reported to inhibit adenosine-mediated bronchoconstriction and bronchial hyperresponsiveness in allergic rabbits. The therapeutic and preventative applications of currently available adenosine Ai receptor-specific antagonists are, nevertheless, limited by their toxicity. Theophylline, for example, has been widely used in the treatment of asthma, but is associated with frequent, significant toxicity resulting from its narrow therapeutic dose range. DPCPX is far too. toxic to be useful clinically. The fact that, despite decades of extensive research, no specific adenosine receptor antagonist is available for clinical use attests to the general toxicity of these agents.

For many years, two classes of compounds have dominated the treatment of asthma: glucocorticosteroids and bronchodilators. Examples of glucocorticosteroids are beclomethasone and corticoid 21-sulfopropionates. Examples of a bronchodilator are an older βl adrenergic agonist such as albuterol, and a newer one such as sahneterol. In general, when glucocorticosteroids are taken daily either by inhalation or orally, they attenuate inflammation. The βl adrenergic agonists, on the other hand, primarily alleviate bronchoconstriction. Whereas glucocorticosteroids are not useful in general for acute settings, bronchodilators are used in acute care, such as in the case of asthma attacks. At the present time, many asthma patients require daily use of both types of agents, a glucocorticosteroid to contain pulmonary inflammation, and a bronchodilator to alleviate bronchoconstriction. More recently, fluticasone propionate, a glucocorticoid steroid was combined with βl adrenergic agonists in one therapeutic formulation said to have greater efficiency in the treatment of asthma. However, glucocorticosteroids, particularly when taken for prolonged periods of time, have extremely deleterious side effects that, although somewhat effective, make their chronic use undesirable, particularly in children.

Accordingly, there is still a need for novel compositions and treatments of ailments afflicting the pulmonary and respiratory tract as well as malignant diseases, including respiratory difficulties, bronchoconstriction, respiratory tract inflammation and allergies, depletion or hyposecretion of surfactant and ubiquinone, etc., which is highly effective and sufficiently selective to avoid detrimental side effects produced by other therapies. In addition, there is a definite need for making available a delivery method that will require low amounts of therapeutic agents and will be effective for the rapid and targeted access of tissue genes of iriRNAs and the reversal of untoward effects afflicting a subject. SUMMARY OF THE INVENTION

The present invention generally relates to a pharmaceutical or veterinary composition, comprising an anti- sense oligonucleotide(s) (oligo(s)) and bronchodilating agents that are effective for alleviating bronchoconstriction, respiratory tract inflammation and allergies, surfactant depletion or hyposecretion, abnormal adenosine or adenosine receptor levels, or ubiquinone depletion, when administered to a subject. The composition comprises a first active agent contains between about 0 to about 15% adenosine (A) and is anti-sense to a target comprising the initiation codon, the coding region, the 5'-end or the 3'-end genomic flanking regions, the 5' or 3' infron-exon junctions, and/or regions within 2 to 10 nucleotides of the junctions of at least one gene encoding or regulating expression of a polypeptide associated with lung airway dysfunction or cancer, or anti-sense to the corresponding mRNA; combinations, multiple target anti-sense oligos (MTAs), or mixtures thereof; a second active agent comprising a bronchodilating agent(s); and a pharmaceutically or veterinarily acceptable carrier or diluent.

The oligo and bronchodilating agent of the invention may be applied to the preparation of a medicament for

(a) reducing adenosine or adenosine receptor levels or sensitivity to adenosine, bronchoconstriction, impeded respiration, respiratory tract inflammation and allergies, surfactant depletion, and other detrimental respiratory tract, pulmonary and cancer associated effects, and for (b) treating specific diseases and conditions such as asthma, cystic fibrosis, pulmonary fibrosis, allergic rhinitis, COPD, etc. The oligos may be directed to any pre-selected target, and in one embodiment they are intended for fast delivery through the mucosal tissue of the lungs or otherwise for hybridization to a desired target polynucleotide to prevent gene franscription and franslation, such that protein expression will be reduced, or completely stopped. The targets for the first active agent(s) are typically molecules associated with airway, lung and cancer disease, and include transcription factors, stimulating and activating peptide factors, cytokines, cytokine receptors, chemokines, chemokine receptors, adenosine receptors, bradykinin receptors, endogenously produced specific and non-specific enzymes, immunoglobulins and antibodies, antibody receptors, central nervous system (CNS) and peripheral nervous and non-nervous system receptors, CNS and peripheral nervous and non-nervous system peptide fransmitters, adhesion molecules, defensins, growth factors, vasoactive peptides and receptors, binding proteins, and malignancy associated proteins, among others. The bronchodilating agents are known in the art as are their dosages.

The oligos and bronchodilating agents are provided for separate and joint administration in the form of individual compositions and formulations, with a carrier or diluent, and optionally with other therapeutic agents and formulation additives for administration by specific routes, e. g. into the respiratory system, topically, fransdermally, parenterally, by implantation, and the like. The oligo and the bronchodilating agent are also provided in a capsule, cartridge or blister, and in the form of a kit.

The drawings accompanying this patent form part of the disclosure of the invention, and further illustrate some aspects of the present invention as discussed below.

BRIEF DESCRIPTION OF THE DRAWINGS Figure 1 illustrates the inhibition of HT-29 SF cells by DHEA.

Figures 2A and 2B illustrate the effects of different amounts of DHEA on cell cycle distribution in HT-29 SF cells.

Figures 3A and 3B illustrate the reversal of DHEA-induced growth inhibition in HT-29 cells treated with CON: Confrol; MVA: Mevalonic Acid; SQ: Squaline; CH: Cholesterol; DN: Deoxyribonucleodies; RN: Ribonucleosides.

Figures 4A, 4B, 4C and 4D illustrate the reversal of DHEA-induced GI arrest in HT-29 SF cells for different durations of treatment with DHEA.

The invention will now be described in general in conceptual and experimental terms, with reference to specific examples. Other objects, advantages and features of the present invention will become apparent to those skilled in the art from the description that follows.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

This invention arose from a desire by the inventor to improve on prior treatments for respiratory, pulmonary, malignant, and other diseases, including his own prior discovery that specifically targeted anti-sense oligonucleotides (oligos) may be utilized preventatively, prophylactically and therapeutically in the treatment of diseases that impair the respiratory tract, including bronchoconstriction, inflammation, allergies, wheezing, dirninished lung function, constricted bronchial tissue, obstructed lung airways, depleted surfactant secretion, or otherwise impeded normal breathing. In general, many diseases are associated with or cause inflammation, constrict bronchial tissue or the lung airways, deplete secretion of surfactant, augment allergies, or otherwise impede normal breathing. This treatment combines the selectivity of antisense oligonucleotides for specific targets associated with or mediating these symptoms, with the bronchodilating effects afforded by different classes of molecules. The oligos are generally administered in low doses and, therefore, evidence minor to no detrimental side effects. The inventor, in addition, wanted to provide a treatment that would improve the outcome and life style of patients undergoing other procedures or being administered other therapies, including antibody therapy, chemotherapy, radiation, phototherapy, and surgery such as cancer and other surgeries, that could be effectively aclministered preventatively, prophylactically or therapeutically. He reasoned that he could further improve on this prior selection of reduced adenosine content oligos by combining anti-sense therapy with the beneficial effects of bronchodilators. The present invention is premised on the discovery by the inventor that the combination of these two very different classes of medicaments would provide a potentiating effect never before seen of their individual beneficial activities.

ARDS' most common symptoms are labored, rapid breathing, nasal flaring, cyanosis blue skin, lips and nails caused by lack of oxygen to the tissues, breathing difficulty, anxiety, stress, tension, joint stiffness, pain and temporarily absent breathing. In the following paragraphs, the specific conditions will be described, and the existing treatments, if any, discussed. ARDS is currently diagnosed by mere symptomatic signs, e. g. chest auscultation with a stethoscope that may reveal abnormal symptomatic breath sounds, and confirmed with chest X-rays and the measurement of arterial blood gas. ARDS, in some instances, appears to be associated with other diseases, such as acute myelogenous leukemia, acute tumor lysis syndrome (ATLS) developed after treatment with, e. g. cytosine arabinoside, etc. In general, however, ARDS is associated with traumatic injury, severe blood infections such as sepsis or other systemic illness, high-dose radiation therapy and chemotherapy, and inflammatory responses which lead to multiple organ failure and in many cases death. In premature babies ("premies"), the lungs are not quite developed and, therefore, the fetus is in an anoxic state during development. Moreover, lung surfactant, a material critical for normal respiration, is generally not yet present in sufficient amounts at this early stage of life; however, premies often hyper-express the adenosine Al receptor and/or underexpress the adenosine A2a receptor and are, therefore, susceptible to respiratory problems including bronchoconstriction, lung inflammation and ARDS, among others. When Respiratory Distress Syndrome (RDS) occurs in premies, it is an extremely serious problem. Preterm infants exhibiting RDS are currently treated by ventilation and aώnrinisfration of oxygen and surfactant preparations. When premies survive RDS, they frequently develop bronchopulmonary dysplasia (BPD), also called chronic lung disease of early infancy, which is often fatal.

Rhinitis may be seasonal or perennial, allergic or non-allergic. Non-allergic rhinitis may be induced by infections, such as viruses, or associated with nasal polyps, as occurs in patients with aspirin idiosyncrasy. Medical conditions such as pregnancy or hypothyroidism and exposure to occupational factors or medications may cause rhinitis. The so-called NARES syndrome is a non-allergic type of rhinitis associated with eosinophils in the nasal secretions, which typically occurs in middle-age and is accompanied by some loss of sense of smell. When cholinergic pathways are stimulated they produce typical secretions that are identified by their glandular constituents so as to implicate neurologic stimulation. Other secretions typical of increased vascular permeability are found in allergic reactions as well as upper respiratory infections, and the degranulation of mast cells releases preformed mediators that interact with various cells, blood vessels, and mucous glands, to produce the typical rhinitis symptoms. Most early- and late-phase reactions occur in the nose after allergen exposure. The late-phase reaction is seen in chronic allergic rhinitis, with hypersecretion and congestion as the most prominent symptoms. When priming occurs, it exhibits a lowered threshold to stimulus after repeated allergen exposure which, in turn, causes a hypersensitivity reaction to one or more allergens. Sufferers may also become hyper-reactive to non-specific triggers such as cold air or strong odors. Self-administered saline improves nasal stuffiness, sneezing, and congestion and usually causes no side effects and it is, thus, the first treatment fried in pregnant patients. Saline sprays are generally used to relieve mucosal irritation or dryness associated with various nasal conditions, minimize mucosal atrophy, and dislodge encrusted or thickened mucus. If used immediately before infranasal corticosteroid dosing, saline sprays may help prevent drug-induced local irritation. Anti-liistamines such as terfenadine and astemizole, two non- sedating anti-lήstamines, are also employed to treat this condition, but have been associated with a ventricular arrhythmia known as Torsades de Points, usually in interaction with other medications such as ketoconazole and erythromycin, or secondary to an underlying cardiac problem. Loratadine, another non-sedating anti-histamine, and cetirizine have not been associated with an adverse impact on the QT interval, or with serious adverse cardiovascular events. Cetirizine, however, produces extreme drowsiness and has not been widely prescribed. Non- sedating anti-Mstamines, e. g. Claritin, may produce some relieving of sneezing, runny nose, and nasal, ocular and palatal itching, but have not been tested for asthma or other more specific conditions. Terfenadine, loratadine and astemizole, on the other hand, exhibit extremely modest bronchodilating effects, reduction of bronchial hyper- reactivity to histamine, and protection against exercise- and antigen-induced bronchospasm. Some of these benefits, however, require higher-man-currently-recommended doses. The sedating-type anti-Mstarnines help induce night sleep, but they cause sleepiness and compromise performance if taken during the day. When employed, anti- histamines are typically combined with a decongestant to help relieve nasal congestion. Sympathomimetic medications are used as vasoconstrictors and decongestants.

The three commonly prescribed systemic decongestants, pseudoephedrine, phenylpropanolamine and phenylephrine cause hypertension, palpitations, tachycardia, restlessness, insomnia and headache. The interaction of phenylpropanolamine with caffeine, in doses of two to three cups of coffee, may significantly raise blood pressure. In addition, medications such as pseudoephedrine may cause hyperactivity in children. Topical decongestants, nevertheless, are only indicated for a limited period of time, as they are associated with a rebound nasal dilatation with overuse. Anti-cholinergic agents are given to patients with significant rhinorrhea or for specific conditions such as "gustatory rhinitis", usually caused by ingestion of spicy foods, and may have some beneficial effects on the common cold. Cromolyn, for example, if used prophylactically as a nasal spray, reduces sneezing, rhinorrhea, and nasal pruritus, and blocks both early- and late-phase hypersensitivity responses, but produces sneezing, transient headache, and even nasal burning. Topical corticosteroids such as Vancenase are somewhat effective in the treatment of rhinitis, especially for symptoms of congestion, sneezing, and runny nose. Depending on the preparation, however, corticosteroid nose sprays may cause irritation, stinging, burning, or sneezing, as well. Local bleeding and septal perforation can also occur sometimes, especially if the aerosol is not aimed properly. Topical steroids generally are more effective than cromolyn sodium, particularly in the treatment of NARES, and also to reduce some symptoms of rhinitis. Their side effects, however, limit their usefulness except for temporary therapy in patients with severe symptoms. These agents are sometimes used for shrinking nasal polyps when local therapy fails. Immunotherapy, while expensive and inconvenient, often provides benefits, especially for inpatients who experience side effects from other medications. So-called blocking antibodies, and agents that alter cellular histamine release, eventually result in decreased IgE, along with many other favorable physiologic changes. This effect is useful in IgE-mediated diseases, e. g., hypersensitivity in atopic patients with recurrent middle ear infections. For allergic rhinitis sufferers, however, a runny nose is more than a nuisance. The disorder often results in impaired quality of life and sets the stage for more serious ailments, including psychological problems. Presently, rhinitis is mostly treated with propranolol, verapamil, and adenosine, all of which have Food and Drug Aώninisfration-approved labeling for acute termination of supravenfricular tachycardia (SVT). There is very little currently available to alleviate symptoms of COPD, prevent exacerbations, preserve optimal lung function, and improve daily living activities and quality of life. Anti-cholinergic drugs achieve short- term bronchodilation and produce some symptom relief in people with COPD, but no improved long-term prognosis even with inhaled products. Most COPD patients have at least some measure of airways obstruction that is somewhat alleviated by iprafropium bromide. "The lung health study" found in men and women smokers spiromefric signs of early COPD. Three treatments compared over a five year period found that iprafropium bromide had no significant effect on the decline in the functional effective volume of the patient's lungs whereas smoking cessation produced a slowing of the decline in the functional effective volume of the lungs. Iprafropium bromide, however, produced serious adverse effects, such as cardiac symptoms, hypertension, skin rashes, and urinary retention. Short and long acting inhaled βl adrenergic agonists achieve short-term bronchodilation and provide some symptomatic relief in COPD patients, but show no meaningful maintenance effect on the progression of the disease.

Short acting βl adrenergic agonists improve symptoms in subjects with COPD, such as increasing exercise capacity and produce some degree of bronchodilation, and even an increase in lung function in some severe cases. The maximum effectiveness of the newer long acting inhaled βl adrenergic agonists was found to be comparable to that of short acting βl adrenergic agonists. Salmeterol was found to improve symptoms and quality of life, although only producing modest or no change in lung function. In asthmatics, however, βl adrenergic agonists have been linked to an increased risk of death, worsened control of astlima, and deterioration in lung function. Continuous tteatment of asthmatic and COPD patients with the bronchodilators iprafropium bromide or fenoterol resulted in a faster decline in lung function, when compared with treatment provided on a need basis, therefore indicating that they are not suitable for maintenance treatment. The most common immediate adverse effect of βl adrenergic agonists, on the other hand, is tremors, which at high doses may cause a fall in plasma potassium, dysrhythmias, and reduced arterial oxygen tension. The combination of a βl adrenergic agonist with an anti-cholinergic drug provides little additional bronchodilation compared with either drug alone. The addition of iprafropium to a standard dose of inhaled βl adrenergic agonists for about 90 days, however, produces some improvement in stable COPD patients over either drag alone. Anti-cholinergic agents were found to produce greater bronchodilation with anti-cholinergic agents than |82 adrenergic agonists in people with COPD. Iprafropium bromide given to patients without bronchodilator therapy, produced an improvement of the functional effective volume of the patient's lungs that was greater when administered in conjunction with an anti-cholinergic agent than with a βl adrenergic agonist, given the residual effect of the anti-cholinergic drug. Overall, the occurrence of some adverse effects with βl adrenergic agonists, such as tremor and dysrhythmias, is more frequent than with anti-cholinergics.

Theophyllines appear to have some bronchodilatory effect in COPD patients whereas they have some common adverse effects, although they have a small therapeutic range given that blood concentrations of 15-20 mg/1 are required for optimal effects. Adverse effects include nausea, diarrhea, headache, irritability, seizures, and cardiac arrhythmias, and they occur at highly variable blood concentrations and, in many people, they occur within the therapeutic range. The theophyllines' doses must be adjusted individually according to smoking habits, infection, and other treatments, wliich is cumbersome. Although theophyllines have been claimed to have an anti-inflammatory effect in asthma, especially at lower doses, none has been reported in COPD, although their bronchodilating short- term effect appears to be statistically different from placebo .

Oral corticosteroids show some improvement in baseline functional effective volume in stable COPD patients whereas systemic corticosteroids have been found to be harmful at least producing some osteoporosis and inducing overt diabetes. The longer term use of oral corticosteroids may be useful in COPD, but it usefulness must be weighed against their substantial adverse effects. Inhaled corticosteroids have been found to have no real short- term effect in airway hyper-responsiveness to histamine, but a small long-term effect on lung function, e. g., in pre- bronchodilator functional effective volume. Fluticasone tteatment of COPD patients showed a significant reduction in moderate and severe (but not mild) exacerbations, and a small but significant improvement in lung function and six minute walking distance. Oral prednisolone, inhaled beclomethasone or both had no effects in COPD patients, but lung function improved oral corticosteroids. Mucolytics have a modest beneficial effect on the frequency and duration of exacerbations but an adverse effect on lung function. Neither N-acetylcysteine nor other mucolytics, however, have a significant effect in people with severe COPD (functional effective volume<50%) in spite of evidencing greater reductions in frequency of exacerbation. N-acetylcysteine produced gastrointestinal side effect. Long-term oxygen therapy administered to hypoxaemic COPD and congestive cardiac failure patients, had little effect on their rates of death for the first 500 days or so, but survival rates in men increased afterwards and remained constant over the next five years. In women, however, oxygen decreased the rates of death throughout the study.

Continuous oxygen treatment of hypoxemic COPD patients (functional effective volume<70% predicted) for 19.3 years decreased overall risk of death. To date, however, only life style changes, smoking cessation and long term treatment with oxygen (in hypoxaemics), have been found to alter the long-term course of COPD.

Although the progress and symptoms of pulmonary fibrosis and other ILDs may vary from person to person, they have one common link: they affect parts of the lung. When inflammation involves the walls of the bronchioles (small airways), it is called bronchiolitis, when it involves the walls and air spaces of the alveoli (air sacs), it is called alveolitis, and when it involves the small blood vessels (capillaries) of the lungs, it is called vasculitis. The inflammation may heal, or it may lead to permanent scarring of the lung tissue, in which case it is called pulmonary fibrosis. This fibrosis or scarring of the lung tissue results in permanent loss of its ability to breathe and carry oxygen, and the amount of scarring determines the level of disability a person experiences because of the destruction by the scar tissue of the air sacs and lung tissue between and surrounding the air sacs and the lung capillaries. When this happens, oxygen is generally aόjmnistered to help improve breathing. Pulmonary fibrosis is caused by, or takes the form of, occupational and environmental exposure to irritants such as asbestos, silica and metal dusts, bacteria and animal dusts, gases and fumes, asbestosis and silicosis, infections that produce lung scarring, of which tuberculosis is one example, connective tissue or collagen diseases such as Rheumatoid Arthritis,

Systemic Sclerosis and Systemic Lupus Erythematosis, idiopathic pulmonary fibrosis and, although not as common, pulmonary fibrosis of genetic/familial origin and certain medicines. Many of the diseases are often named after the occupations with which they are associated, such as Grain handler's lung, Mushroom worker's lung, Bagassosis, Detergent worker's lung, Maple bark stripper's lung, Malt worker's lung, Paprika splitter's lung, and Bird breeder's lung. "Idiopathic" (of unknown origin) pulmonary fibrosis (IPF) is the label applied when all other causes of interstitial lung disease have been ruled out, and is said to be caused by viral illness and allergic or environmental exposure (including tobacco smoke). Bacteria and other microorganisms are not thought to be a cause of IPF. There is also a familial form of the disease, known as familial idiopathic pulmonary fibrosis whose main symptom is shortness of breath. Since many lung diseases show this symptom, making a correct diagnosis is often difficult. The shortness of breath may first appear during exercise and the condition may progress then to the point where any exertion is impossible. Eventually resulting in shortness of breath even at rest. Other symptoms may include a dry cough (without sputum), and clubbing of the fingertips. Glucocorticosteroids are usually administered to treat inflammation present in pulmonary fibrosis, with inconclusive results. Other drugs, however, are not usually added until it is clear that the steroids are not effective in reversing the disease. Glucocorticosteroids are also used in combination with other drugs when a diagnosis is first established., for example oxygen therapy prescribed in severe cases. The adminisfration of influenza and pneumococcal pneumonia vaccines is often recommended in pulmonary fibrosis and more generally for all lung diseases to prevent infection. The tteatment and management of pulmonary fibrosis often requires a lung biopsy to assess the unpredictable response of patients to glucocorticosteroids or other immune system suppressants. Lung transplants are sometimes an ultimate option in severe cases of pulmonary fibrosis and other lung diseases. Pulmonary fibrosis may also be caused by other specific diseases, such as sarcoidosis, a disease whose cause is unknown, that is characterized by the formation of granulomas or areas of inflammatory cells. The disease may attack any organ of the body, but most frequently attacks the lungs, and is generally diagnosed when a chest x-ray shows enlarged lymph glands in the center of both lungs or evidence of lung tissue thickening. For many sarcoidosis is a minor problem, and symptoms including dry cough, shortness of breath, mild chest pain, fatigue, weakness and weight loss-may appear infrequently and stop even without medication. For others, it is a serious, disabling disease that affects African-americans more than members of any other race, although almost everybody may develop the disease, most common in young adults 20 to 40. Histiocytosis X, also associated with pulmonary fibrosis, seems to begin in the bronchioles or small airways of the lungs and their associated arteries and veins, and is generally followed by destruction of the bronchioles and narrowing and damaging of small blood vessels. It is diagnosed by a bronchoalveolar lavage test involving the removal and identification of cells from the lower respiratory tract. Symptoms of this disease include a dry cough

(without sputum), breathlessness upon exertion, and/or chest pain. In approximately 50% of tlie cases, the disease is chronic with loss of lung function, and although glucocorticosteroid therapy is often prescribed, there is no evidence that it is effective. Many histiocytosis X sufferers are current or former cigarette smokers, although its association with smoking is not well understood. Many jobs, particularly those that involve rrrining or that expose workers to asbestos or metal dusts, may cause pulmonary fibrosis by inhalation of small particulate matter, e. g. dust or asbestos fibers that damage the lungs, especially the small airways and air sacs, and cause scarring (fibrosis). Agricultural workers are also affected by some particulate organic substances, such as moldy hay, which cause an allergic reaction in the lung called "Farmer's Lung", and may cause pulmonary fibrosis as well.

Asbestosis and silicosis are two occupational lung diseases whose causes are known. Asbestosis is caused by small needle-like particles of asbestos inhaled into the lungs, and cause lung scarring or pulmonary fibrosis that may lead to lung cancer. Silicosis is a dust disease that comes from breathing in free crystalline silica dust, and is produced by all types of mining in which the ore, e. g. gold, lead, zinc, copper, iron, anthracite (hard) coal, and some bituminous (soft) coal, are extracted from quartz rock. Workers in foundries, sandstone grinding, tunneling, sandblasting, concrete breaking, granite carving, and china manufacturing also encounter silica. Large silica particles are stopped in the upper airways, but the tiniest specks of silica are carried down to the lung alveoli, where they lead to pulmonary fibrosis. The use of glucocorticosteroids alone, or combined drug therapy, and the hope of lung transplant are three freatment approaches that are currently being tested, but up to the present time there is no good therapy for this disease. This patent provides the first effective therapy for these and other respiratory and lung ailments. When oligonucleotides are metabolized in vivo, those that contain adenosine (A) break down and release amounts of this purine that, in turn, activates adenosine receptors and cause bronchoconstriction, inflammation, surfactant depletion, and respiratory tract allergies, among other symptoms. The inventor, thus, conceived of employing low adenosine and adenosine free oligos to avoid these side effects upon their adminisfration. This patent thus also includes novel and improved compositions, formulations and methods employing these oligos and bronchodilating agents, that afford greatly improved results when compared with previously known treatments for bronchoconstriction, allergies, inflammation, breathing difficulties, surfactant depletion and blockage of airways, as well as for other conditions which affect the lung directly or indirectly. In different embodiments, one or more nucleic acids of the invention may be formulated alone, with one or more bronchodilating agents and/or with one or more surfactant components and a carrier, and optionally with other therapeutic agents and formulation agents. The compositions of this invention may be incorporated into a variety of formulations for systemic and topical atϊminisfration that are described below in some detail. A preferred method for the delivery of anti-sense oligonucleotides (oligos) and bronchodilating agents, however, is through the respiratory system, as a fast means of jump-starting treatment to address acute attacks of asthma and other diseases that have a rapid onset while providing long term relief and improving a patient's quality of life. In addition, the oligos have long half-lives, and are generally administered at very low doses, which makes them ideal for once-a-week type therapies.

The respiratory system, and in particular the lung, as the ultimate port of entry into the organism, however, is an excellent route of administration for anti-sense oligonucleotides. This is so not only for the treatment of lung disease, but also when utilizing the lung as a means for delivery, particularly because of its non-invasive and tissue- specific nature. Thus, local delivery of antisense oligonucleotides directly to the target tissue enables the therapeutic use of these compounds. Fomivirsen (ISIS 2922) is an example of a local drug delivery into the eye to treat cytomegalovirus (CMV) retinitis, for which a new drug application has been filed by ISIS. The administration of a drag through the lung offers the further advantage that inhalation is non-invasive whereas direct injection in to the vitreous of the eye is invasive. The composition and formulations of this invention are highly efficacious for preventing and treating diseases and conditions associated with bronchoconstriction, difficult breathing, impeded and obstructed lung airways, allergy(ies), inflammation and surfactant depletion, among others. Examples of diseases and conditions which are suitably treated by the present method, include Acute Respiratory Distress Syndrome (ARDS), asthma, adenosine administration, e. g. in the treatment of Supra Ventricular Tachycardia (SVT) and other arrhythmias, and in stress tests to hyper-sensitized individuals, ischemia, renal damage or failure induced by certain drugs, infantile respiratory distress syndrome, pain, cystic fibrosis, pulmonary hypertension, pulmonary vasoconstriction, emphysema, chronic obstructive pulmonary disease (COPD), lung transplantation rejection, pulmonary infections, and cancers such as leukemias, lymphomas, carcinomas, and the like, including colon cancer, breast cancer, lung cancer, pancreatic cancer, hepatocellular carcinoma, kidney cancer, melanoma, hepatic metastases, etc., as well as all types of cancers which may metastasize or have metastasized to the lung(s), including breast and prostate cancer. The invention will be described with respect to the oligos by employing adenosine receptors as targets, but is similarly applicable to any other target with respect to the pulmonary administration of anti-sense oligos. The examples provided below show complete inhibition of various adenosine receptor and bradykinin associated symptoms in a rabbit model for human bronchoconstriction, allergies and inflammation as well as the elirnination of the ability of the adenosine receptor agonist par excellence, adenosine, to cause bronchoconstriction in hyper-responsive monkeys, which are animal models for human hyper-responsiveness to adenosine receptor agonists. The pharmaceutical composition and formulations of the invention, therefore, are suitable for preventing and alleviating the symptoms associated with stimulation of, for example, adenosine receptors, such as the adenosine Al, A2b and A3 receptors. The compositions and formulations of this invention, thus, are also suitable for prevent the untoward side effects of adenosine-mediated hyperresponsiveness in certain individuals, which are generally seen in diseases affecting respiratory activity.

The method of the present invention may be used to treat airway, lung and cancer diseases and conditions of any kind, origin and for any reason, with the intention that the reduced adenosine content anti-sense compounds will produce a minimum liberation of adenosine upon its degradation.

Examples of diseases and conditions, which may be treated preventatively, prophylactically and therapeutically with the compositions and formulations of this invention, are pulmonary vasoconstriction, inflammation, allergies, asthma, allergic rhinitis, impeded respiration, Acute Respiratory Distress Syndrome (ARDS), renal damage and failure associated with ischemia as well as the aiirninistration of certain drugs, side effects associated with adenosine administration e. g. in Supra Ventricular Tachycardia (SVT) and in adenosine stress tests, infantile Respiratory Distress Syndrome (infantile RDS), ARDS, pain, cystic fibrosis, pulmonary hypertension, pulmonary vasoconstriction, emphysema, chronic obstructive pulmonary disease (COPD), lung transplantation rejection, pulmonary infections, and cancers such as leukemias, lymphomas, carcinomas, and the like, e. g. colon cancer, breast cancer, lung cancer, pancreatic cancer, hepatocellular carcinoma, kidney cancer, melanoma, metastatic cancer such as hepatic metastases, lung, breast and prostate metastases, among others. The present compositions and formulations are suitable for adminisfration before, during and after other freatments, including radiation, chemotherapy, antibody therapy, phototherapy and cancer, and other types of surgery. The present compositions and formulations may also be administered effectively as a substitute for therapies that have significant negative side effects. The terms "anti-sense" oligonucleotides generally refers to small, synthetic oligonucleotides, resembling single-stranded DNA, which in this patent are applied to the inhibition of gene expression by inhibition of a target messenger RNA (mRNA). See, Milligan, J. F. et al., J. Med. Chem. 36(14), 1923-1937 (1993), the relevant portion of which is hereby incorporated in its entirety by reference. For consistency's sake, all RNAs and oligonucleotides are represented in this patent by a single strand in the 5' to 3' direction, when read from left to right, although their complementary sequence(s) is (are) also encompassed within the four corners of the invention. In addition, all nucleotide bases and amino acids are represented utilizing the recommendations of the IUPAC-IUB Biochemical Nomenclature Commission, or by the known 3-letter code (for amino acids). Nucleotide sequences are presented herein by single strand only, in the 5' to 3' direction, from left to right. In addition, nucleotide and amino acids are represented herein in the manner recommended by the IUPAC- IUB Biochemical Nomenclature Commission, or (for amino acids) by three letter code, in accordance with 37 CFR ' 1.822 and established usage. See, e. g., Patentln User Manual, 99-102 (Nov. 1990) (U.S. Patent and Trademark Office, Office of the Assistant Commissioner for Patents, Washington, D.C. 20231); U.S. Patent No. 4,871,670 to Hudson et al. at col. 3, lines 20-43. The present method utilizes anti-sense agents to inhibit or down-regulate gene expression of target genes, including those listed in Tables 1 and 2 below. This is generally attained by hybridization of the anti-sense oligonucleotides to coding (sense) sequences of a targeted messenger RNA (mRNA), as is known in the art. The exogenously administered agents of the invention decrease the levels of mRNA and protein encoded by the target gene and/or cause changes in the growth characteristics or shapes of the thus treated cells. See, Milligan et al. (1993); Helene, C. and Toulme, J. Biochim. Biophys. Acta 1049, 99-125 (1990); Cohen, J. S. D.,

Ed., Oligodeoxynucleotides as Anti-sense Inhibitors of Gene Expression; CRC Press: Boca Raton, FL (1987), the relevant portion of which is hereby incorporated in its entirety by reference.

As used herein, "anti-sense oligonucleotide or anti-sense oligo" is generally a short sequence of synthetic nucleotide that (1) hybridizes to any segment of a mRNA encoding a targeted protein under appropriate hybridization conditions, and which (2) upon hybridization causes a decrease in gene expression of the targeted protein. The terms "desAdenosine" (desA), "desUridine" (desU), and "des-thymidine" (desT) refer to oligonucleotides substantially lacking either adenosine (desA), uridine (desU) or thymidine (desT). In some instances, the des A, desU or des T sequences are naturally occurring, and in others they may result from substitution of an undesirable nucleotide (A) by another lacking its undesirable activity, such as acting as an agonist or having a triggering effect at the adenosine A receptor(s). In the present context, the substitution is generally accomplished by substitution of A with a "universal or alternative base", presently known in the art or to be ascertained at a later time. As used herein, the terms "prevent", "preventing", "treat" or "treating" refer to a preventative, prophylactic, maintenance, or therapeutic treatment which decreases the likelihood that the subject aclministered such freatment will manifest symptoms associated with adenosine receptor stimulation. The term "down-regulate" refers to inducing a decrease in production, secretion or availability and, thus, a decrease in concentration, of intracellular target product, be it a receptor, e. g. adenosine A_b A₂ , A₃, bradykinin 2B, GATA-3, or other receptors, or an increase in concentration of the adenosine A_2a receptor. The present technology relies on the design of anti-sense oligos targeted to mRNAs associated with ailments involving lung airway ρathology(ies), and on their modification to reduce the occurrence of undesirable side effects caused by their release of adenosine upon breakdown, while preserving their activity and efficacy for their intended purpose. In this manner, the anti- sense oligos target a specific gene to design one or more anti-sense oligonucleotide(s) (oligos) that selectively bind(s) to the corresponding mRNA, and then reduces, if necessary, their content of adenosine via substitution with an alternative or a universal base, or an adenosine analog incapable of significantly, or having substantially reduced ability for, activating or antagonizing adenosine Ai, A_2b or A₃ receptors or which may act as an agonist at the adenosine A_2a, receptor. Any number of adenosines present may be substituted by an alternative and or universal base, such as heteroaromatic bases, wliich binds to a thymidine or uridine base but has less than about 0.3 of the adenosine base agonist or antagonist activity at the adenosine A A_2a, A_2b and A₃ receptors. Based on the inventor's prior experience in the field, the inventor reasoned that in addition to "downregulating" specific genes, he could increase the effect of the agent(s) administered by either selecting segments of RNA that are devoid, or have a low content, of thymidine (T) or uridine (U) or, alternatively, substitute one or more adenosine(s) present in the designed oligonucleotide(s) with other nucleotide bases, so called universal bases, which bind to thymidine but lack the ability to activate adenosine receptors and otherwise exercise the constricting effect of adenosine in the lungs, etc.

Given that adenosine (A) is a nucleotide base complementary to thymidine (T) or uridine (U), when a T or U appears in the DNA or RNA, the anti-sense oligo will have an A at the same position.

In one aspect of this invention, the anti-sense oligonucleotide has a sequence wliich specifically binds to a portion or segment of a mRNA molecule which encodes a protein associated with impeded breathing, allergies, lung inflammation, depletion of lung surfactant or lowering of lung surfactant, airway obstruction, bronchitis, and the like. One effect of this binding is to reduce or even prevent the franslation of the corresponding mRNA and, thereby, reduce the available amount of target protein in the subject's lung. In one preferred embodiment of this invention, the phosphodiester residues of the anti-sense oligonucleotide are modified or substituted. Chemical analogs of oligonucleotides with modified or substituted phosphodiester residues, e. g., to the methylphosphonate, the phosphofriester, the phosphorothioate, the phosphorodithioate, or the phosphoramidate, α' methoxy ethyl and similar modifications, which increase the in vivo stability of the oligonucleotide are particularly preferred. The naturally occurring phosphodiester linkages of oligonucleotides are susceptible to some degree of degradation by cellular nucleases. Many of the residues proposed herein, on the contrary, are highly resistant to nuclease degradation. See, Milligan et al.; Cohen, J. S. D., supra. In another preferred embodiment of the invention, the oligonucleotides may be protected from degradation by adding a "3'-end cap" by which nuclease-resistant linkages are substituted for phosphodiester linkages at the 3' end of the oligonucleotide. See, Tidd, D. M. and Warenius, H.M., Be. J. Cancer 60: 343-350 (1989); Shaw, J.P. et al., Nucleic Acids Res. 19: 747-750 (1991), the relevant section of wliich are incorporated in their entireties herein by reference. Phosphoramidates, phosphorothioates, and methylphosphonate linkages all function adequately in this manner for the purposes of this invention, as do α' modifications, such as oϋ methoxy ethyl, and the like. The more extensive the modification of the phosphodiester backbone the more stable the resulting agent, and in many instances the higher their RNA affinity and cellular permeation. See, Milligan, et al., supra. In addition, a plurality of substitutions to the carbohydrate ring are also known to improve stability of nucleic acids. Thus, the number of residues which may be modified or substituted will vary depending on the need, target, and route of administration, and may be from 1 to all the residues, to any number in between. Many different methods for replacing the entire phosphodiester backbone with novel linkages are known. See, Millikan et al, supra. Preferred backbone analogue residues include phosphoramidate, phosphorothioate, methylphosphonate, phosphorofriester, phosphofriester, thioformacetal, phosphorodithioate, phosphoramidate, formacetal, friformacetal, thioether, carbamate, boranophosphate, 3 -thioformacetal, 5'-thioether, carbonate, C₅-substituted nucleotides, 5'-N-carbamate, sulfate, sulfonate, sulfamate, sulfonamide, sulfone, sulfite, 2'- O methyl, sulfoxide, sulfide, hydroxylamine, metiιylene(memylimino) (MMI), methoxymethyl (MOM), and methoxyethyl(MOE), and methyleneoxy(methylimino) (MOMI) residues, and combinations thereof. Phosphorothioate and methylphosphonate-modified oligonucleotides are particularly preferred due to their availability through automated oligonucleotide synthesis. See, Millikan et al, supra. Where appropriate, the agent of this invention may be administered in the form of their pharmaceutically acceptable salts, or as a mixture of the anti- sense oligonucleotide and its salt. In another embodiment of this invention, a mixture of different anti-sense oligonucleotides or their pharmaceutically acceptable salts is administered.

A single oligo of this invention has the capacity to attenuate the expression of a target mRNA and/or various agents to enhance or attenuate the activity of a pathway whereas the bronchodilating agent facilitates the opening of the airways and promotes an increase in the pulmonary function of the patient. By means of example, the present method may be practiced by identifying all possible deoxyribonucleotide or ribonucleotide segments which are low in thymidine (T) or uridine (U), or deoxynucleotide segments low in adenosine (A) of about 7 or more mononucleotides, preferably up to about 60 mononucleotides, more preferably about 10 to about 36 mononucleotides, and still more preferably about 12 to about 21 mononucleotides, in a target mRNA or a gene, respectively. This may be attained by searching for mononucleotide segments within a target sequence which are low in, or lack thymidine (RNA), a nucleotide which is complementary to adenosine, or that are low in adenosine

(gene), that are 7 or more nucleotides long. In most cases, this search typically results in about 10 to 30 such sequences, i. e. naturally lacking or having less than about 40% adenosine, anti-sense oligonucleotides of varying lengths for a typical target mRNA of average length, i. e., about 1800 nucleotides long. Those with high content of T, U or A, respectively, may be fixed by substitution of a universal base for one or more As. The first active agent(s) of this invention may be of any suitable length, including but not limited to, about 7 to about 60 nucleotides long, preferably about 12 to about 45, more preferably up to about 30 nucleotides long, and still more preferably up to about 21, although they may be of other lengths as well, depending on the particular target and the mode of delivery. The agent(s) of the invention may be directed to any and all segments of a target RNA. One preferred group of agent(s) includes those directed to an mRNA region containing a junction between an intton and an exon. Where the first agent is directed to an infron/exon junction, it may either entirely overlie the junction or it may be sufficiently close to the junction to inhibit the splicing-out of the intervening exon during processing of precursor mRNA to mature mRNA, e. g. with the 3' or 5' terminus of the anti-sense oligonucleotide being positioned within about, for example, within about 2 to 10, preferably about 3 to 5, nucleotide of the intron/exon junction. Also preferred are anti-sense oligonucleotides which overlap the initiation codon, and those near the 5' and 3' termini of the coding region. The flanking regions of the exons may also be targeted as well as the spliced segments in the precursor mRNAs. The mRNA sequences of the adenosine receptors and of many other targets are derived from the DNA base sequence of the gene expressing either receptors, e. g. the adenosine receptors, the enzymes, factors, or other targets associated with airway disease. For example, the sequence of the genomic human Ai adenosine receptor is known and is disclosed in U.S. Patent No. 5,320,963 to Stiles, G., et al. The A₃ adenosine receptor has been cloned, sequenced and expressed in rat (see, Zhou, F., et al., P.N.A.S. (USA) 89: 7432 (1992)) and human (see, Jacobson, M. A., et al., U.K. Patent Application No. 9304582.1 (1993)). The sequence of the adenosine A_2b receptor gene is also known. See, Salvatore, C. A., Luneau, C. J., Johnson, R. G. and Jacobson, M., Genomics

(1995), the relevant portion of wliich is hereby incorporated in its entirety by reference. The sequences of many of the remaining exemplary target genes are also known. See, GenBank, NIH. The sequences of those genes whose sequences are not yet available may be obtained by isolating the target segments applying technology known in the art. Once the sequence of the gene, its RNA and or the protein are known, an anti-sense oligonucleotides may be produced according to this invention as described above to reduce the production of the targeted protein in accordance with standard techniques. The sequences for the adenosine A_2a bradykinin, and other genes as well as methods for preparation of oligonucleotides are also known as those of many other target genes and mRNAs for which this invention is suitable. Thus, anti-sense oligonucleotides that downregulate the production of target sequences associated with airway disease, including the adenosine A A_2a, A_2b, A₃, bradykinin, GATA-3, COX-2, and many other receptors, may be produced in accordance with standard techniques.

Examples of bronchodilating agents are ubiquinones, glucocorticosteroids, adenosine receptor antagonists such as theophyllines, anti-cholinergics, anti-histamines, and βl adrenergic agonists, amongst others.

Examples of βl adrenergic agonists are ephedrine, isoproterenol, isoetharine, epinephrine, metaproterenol, terbutaline, fenoterol, procaterol, albuterol, salmeterol, pirbuterol, formoterol, biloterol, bambuterol, salbutamol, and seretide, among others. Examples of glucocorticosteroids, such as beclomethasone, corticoid 21- sulfopropionates, (16 alpha)-16,17-alkylidene bis (oxy)-3-arylpregna-2,4-trien-20-ones, hydrocortisone esters, cyproterone thiopivalate (CTP), hydrocortisone, dexamethasone trimethyl acetate, alkane sulfonic acids of decinine, α-hydroxyprednisolone, 18,18-difluorosteroids, preparing 17-alpha-hydroxy corticoid 21-phosphate, 21-phosphate corticoids having unprotected hydroxyl radicals at least at the 17-alρha- and 21 -position, 16-alpha-methylated δ- 17(20)-corticoids, 21-(L-ascorbyl-2-phosphoryl) dexamethasone, 21-(L-ascorbyl-2-phosphoryl) hydrocortisone, 21-

(L-ascorbyl-2-ρhosphoryl) friamcinolone acetonide and physiologically acceptable salts thereof, among others. Some of these are effective for short periods of time, but in conjunction with the non-glucocorticoid steroids provide a good combination of short and long term relief.

^■ The daily dosage of the bronchodilators and the optional anti-inflammatory glucocorticosteroid to be administered to a subject will vary with the overall treatment programmed, the agent employed, the type of formulation, the route of adminisfration and the state of the patient. A large number of bronchodilators and anti- inflammatory glucocorticosteroids are known in the art, and are commercially available. Their use is widespread and their broad range of dosages are in the public domain. See, e. g. US. Patent 5,270,350 for salmeterol. Examples 36 to 48 show aerosolized preparations in accordance with the invention for delivery with a device for respiratory or nasal aclminisfration, or adrninisfration by inhalation. For infrapulmonary administration, liquid preparations are preferred. In the case of other bioactive agents, there exist FDA recommended amounts for supplementing a person's dietary intake with additional bioactive agents, such as in the case of vitamins and minerals. However, where employed for the tteatment of specific conditions or for improving the immune response of a subject they may be utilized in dosages hundreds and thousands of times higher. Mostly, the pharmacopeia's recommendations cover a very broad range of dosages, from which the medical artisan may draw guidance. Amounts for the exemplary agents described in this patent may be in the range of those currently being recommended for daily consumption, below or above those levels. The treatment may typically begin with a low dose of a bronchodilator in combination with a n anti-sense oligo, and optionally other therapeutic agents, including glucocorticoid steroids, mucolytics, anti- histamines, anti-cholinergic agents, and other bioactive agents as appropriate, and then a titration up of the dosage for each patient. Higher and smaller amounts, including initial amounts, however, may be administered within the confines of this invention as well. Other agents that may be incorporated into the present composition are one or more of a variety of therapeutic agents that are aclministered to humans and animals. Some of the categories of agents suitable for incorporation into the present composition and formulations are analgesics, pre-menstrual medications, menopausal agents, anti-aging agents, anti-anxyolytic agents, mood disorder agents, anti-depressants, anti-bipolar mood agents, anti-schizophrenic agents, anti-cancer agents, alkaloids, blood pressure controlling agents, hormones, anti- inflammatory agents, muscle relaxants, steroids, soporific agents, anti-ischemic agents, anti-arrhythmic agents, contraceptives, vitamins, minerals, ttanquilizers, neurofransmitter regulating agents, wound healing agents, anti- angiogenic agents, cytokines, growth factors, anti-metastatic agents, antacids, anti-Wstaminic agents, anti-bacterial agents, anti-viral agents, anti-gas agents, appetite suppressants, sun screens, emollients, skin temperature lowering products, radioactive phosphorescent and fluorescent contrast diagnostic and imaging agents, libido altering agents, bile acids, laxatives, anti-diarrheic agents, skin renewal agents, hair growth agents, analgesics, pre-menstrual medications, anti-menopausal agents such as hormones and the like, anti-aging agents, anti-anxiolytic agents, nociceptic agents, mood disorder agents, anti-depressants, anti-bipolar mood agents, anti-schizophrenic agents, anti- cancer agents, alkaloids, blood pressure controlling agents, hormones, anti-inflammatory agents, other agents suitable for the treatment and prophylaxis of diseases and conditions associated or accompanied with pain and inflammation, such as arthritis, burns, wounds, chronic bronchitis, chronic obstructive pulmonary disease (COPD), inflammatory bowel disease such as Crohn's disease and ulcerative colitis, autoimmune disease such as lupus erythematosus, muscle relaxants, steroids, soporific agents, anti-ischemic agents, anti-arrhythmic agents, contraceptives, vitamins, minerals, ttanquilizers, neurofransmitter regulating agents, wound and burn healing agents, anti-angiogenic agents, cytokines, growth factors, anti-metastatic agents, antacids, anti-histaminic agents, anti- bacterial agents, anti-viral agents, anti-gas agents, agents for reperfusion injury, counteracting appetite suppressants, sun screens, emollients, skin temperature lowering products, radioactive phosphorescent and fluorescent contrast diagnostic and imaging agents, libido altering agents, bile acids, laxatives, anti-diarrheic agents, skin renewal agents, hair growth agents, etc.

Among the hormones are female and male sex hormones such as premarin, progesterone, androsterones and their analogues, thyroxine and glucocorticoids, among the libido altering agents are Viagra and other NO-level modulating agents, among the analgesics are over-the-counter medications such as ibuprofen, oruda, aleve and acetaminophen and controlled substances such as morphine and codeine, among the anti-depressants are fricyclics, MAO inhibitors and epinephrine, γ-amino butyric acid (GABA), dopamine and serotonin level elevating agents, e. g. Prozac, Amytryptilm, Wellbufrin and Zoloft, among the skin renewal agents are Retin-A, hair growth agents such as Rogaine, among the anti-inflammatory agents are non-steroidal anti-inflammatory drugs (NSAIDs) and steroids, among the soporifics are melatonin and sleep inducing agents such as diazepam, cytoprotective, anti- ischemic and head injury agents such as enadoline, and many others. Examples of agents in the different groups are provided in the following list. Examples of analgesics are Acetorninophen, Anilerdine, Aspirin, Buprenorphine, Butabital, Butorpphanol, Choline Salicylate, Codeine, Dezocine, Diclofenac, Diflunisal, Dihydrocodeine, Elcatoninin, Etodolac, Fenoprofen, Hydrocodone, Hydromorphone, Ibuprofen, Ketoprofen, Ketorolac, Levorphanol,

Magnesium Salicylate, Meclofenamate, Mefenamic Acid, Meperidine, Methadone, Methofrimeprazine, Morphine, Nalbuphine, Naproxen, Opium, Oxycodone, Oxymorphone, Pentazocine, Phenobarbital, Propoxyphene, Salsalate, Sodium Salicylate, Tramadol and Narcotic analgesics in addition to those listed above. See, Mosby's Physician's GenRx. Examples of anti-anxiety agents include Alprazolam, Bromazepam, Buspirone, Chlordiazepoxide, Chlormezanone, Clorazepate, Diazepam, Halazepam, Hydroxyzine, Ketaszolam, Lorazepa , Meprobamate,

Oxazepam and Prazepa , among others. Examples of anti-anxiety agents associated with mental depression are Chlordiazepoxide, Amitriptyline, Loxapine Maprotiline and Perphenazine, among others. Examples of anti- inflammatory agents are non-rheumatic Aspirin, Choline Salicylate, Diclofenac, Diflunisal, Etodolac, Fenoprofen, Floctafenine, Flurbiprofen, Ibuprofen, Indomethacin, Ketoprofen, Magnesium Salicylate, Meclofenamate, Mefenamic Acid, Nabumetone, Naproxen, Oxaprozin, Phenylbutazone, Piroxicam, Salsalate, Sodium Salicylate, Sulindac, Tenoxicam, Tiaprofenic Acid, Tolmetin. Examples of anti-inflammatories for ocular tteatment are Diclofenac, Flurbiprofen, Indomethacin, Ketorolac, Rimexolone (generally for post-operative treatment). Examples of anti-inflammatories for non-infectious nasal applications are Beclomethaxone, Budesonide, Dexamethasone, Flunisolide, Triamcinolone, and the like. Examples of soporifics (anti-insomnia/sleep inducing agents) such as those utilized for treatment of insomnia, are Alprazolam, Bromazepam, Diazepam, Diphenhydramine, Doxylamine, Estazolam, Flurazepam, Halazepam, Ketazolam, Lorazepam, Nitrazepam, Prazepam Quazepam, Temazepam, Triazolam, Zolpidem and Sopiclone, among others. Examples of sedatives are Diphenhydramine, Hydroxyzine,

Methotrimeprazine, Promethazine, Propofol, Melatonin, Trimeprazine, and the like. Examples of sedatives and agents used for tteatment of petit mal and tremors, among other conditions, are Amitriptyline HCl, Chlordiazepoxide, Amobarbital, Secobarbital, Aprobarbital, Butabarbital, Ethchiorvynol, Glutethimide, L- Tryptophan, Mephobarbital, MethoHexital Na, Midazolam HCl, Oxazepam, Pentobarbital Na, Phenobarbital, Secobarbital Na, Thiamylal Na, and many others. Agents used in the freatment of head trauma (Brain

Injury/Ischemia) include Enadoline HCl (e. g. for freatment of severe head injury, orphan status, Warner Lambert). Examples of cytoprotective agents and agents for the tteatment of menopause and menopausal symptoms are Ergotamine, Belladonna Alkaloids and Phenobarbitals. Examples of agents for the treatment of menopausal vasomotor symptoms are Clonidine, Conjugated Estrogens and Medroxyprogesterone, Estradiol, Esttadiol Cypionate, Esttadiol Valerate, Estrogens, conjugated Estrogens, esterified Esttone, Esttopipate and Ethinyl

Esttadiol. Examples of agents for tteatment of symptoms of Pre Menstrual Syndrome (PMS) are Progesterone, Progesrin, Gonadotrophic Releasing Hormone, oral contraceptives, Danazol, Luprolide Acetate and Vitamin B6. Examples of agents for the freatment of emotional/psychiatric treatments are Tricyclic Antidepressants including Amittiptyline HCl (Elavil), Amittiptyline HCl, Perphenazine (Triavil) and Doxepin HCl (Sinequan). Examples of ttanquilizers, anti-depressants and anti-anxiety agents are Diazepam (Valium), Lorazepam (Ativan), Alprazolam

(Xanax), SSRI's (selective Serotonin reuptake inhibitors), Fluoxetine HCl (Prozac), Sertaline HCl (Zoloft), Paroxetine HCl (Paxil), Fluvoxamine Maleate (Luvox), Venlafaxine HCl (Effexor), Serotonin, Serotonin Agonists (Fenfluramine), and other over the counter (OTC) medications. Examples of anti-migraine agents are Imiteex and the like. The active agents of this invention are provided within broad amounts of the composition. For example, the active agents may be contained in the composition in amounts of about 0.001%, about 1%, about 2%, about 5%, about 10%, about 20%, about 40%, about 90%, about 98%, about 99.999% of the composition. The amount of each active agent may be adjusted when, and if, additional agents with overlapping activities are included as discussed in this patent. The dosage of the active compounds, however, may vary depending on age, weight and condition of the subject. Treatment may be initiated with a small dosage, e. g. less than the optimal dose, of the first active agent of the invention, and optionally other bioactive agents described above. This may be similarly done with the second active agent, until a desirable level is attained. Or vice versa, for example in the case of multivitamins and/or minerals, the subject may be stabilized at a desired level of these products and then administered the first active compound. The dose may be increased until a desired and/or optimal effect under the circumstances is reached. In general, the active agent is preferably administered at a concentration that will afford effective results without causing any unduly harmful or deleterious side effects, and may be aiiministered either as a single unit dose, or if desired in convenient subunits administered at suitable times throughout the day. The therapeutic or diagnostic agent(s) is (are) administered in amounts which are known in the art to be effective for the intended application. In cases where the second agent has an overlapping activity with the principal agent, the dose of one of the other or of both agents may be adjusted to attain a desirable effect without exceeding a dose range that avoids untoward side effects. Thus, for example, when other analgesic and anti-inflammatory agents are added to the composition, they may be added in amounts known in the art for their intended application or in doses somewhat lower that when administered by themselves.

Examples of diseases and conditions which are suitably treated by the present method are diseases and conditions, including Acute Respiratory Distress Syndrome (ARDS), asthma, adenosine administration e. g. in the treatment of SupraVenfricular Tachycardia (SVT) and other arrhythmias, and in stress tests to hyper-sensitized individuals, ischemia, renal damage or failure induced by certain drugs, infantile respiratory distress syndrome, pain, cystic fibrosis, pulmonary hypertension, pulmonary vasoconstriction, emphysema, chronic obstructive pulmonary disease (COPD), pulmonary transplantation rejection, pulmonary infections, and cancers such as leukemias, lymphomas, carcinomas, and the like, including colon cancer, breast cancer, lung cancer, pancreatic cancer, hepatocellular carcinoma, kidney cancer, melanoma, hepatic metastases, etc., as well as all types of cancers which may metastasize or have metastasized to the lung(s), including breast and prostate cancer. Preferable ranges for the first, second and other agents employed here will vary depending on the disease they applied to treat and how advanced it is, the state of the patient, the route of administration and type of formulation employed, as an artisan will appreciate and manufacture in accordance with known procedures and components. The active compounds may be administered as a once-a-week dose, once-a-day doe, or several times a day. The compositions and method of preventing and treating respiratory, cardiac, cardiovascular and neoplastic diseases, among others, including aging, may be used to treat adults and infants, as well as non-human animals afflicted with the described conditions. Although the present invention is concerned primarily with the tteatment of human subjects, it may also be employed, for veterinary purposes in the tteatment of other mammalian subjects, such as dogs and cats as well as for large domestic and wild animals. The terms "high" and "low" levels of "adenosine" and "adenosine receptors" as well as "adenosine depletion" are intended to encompass both, conditions where adenosine levels are higher than, or lower (even depleted) when compared to previous adenosine levels in the same subject, and conditions where adenosine levels are within the normal range but, because of some other condition or alteration in that patient, a therapeutic benefit would be achieved in the patient by decreasing or increasing adenosine or adenosine receptor levels or hypersensitivity. Thus, this treatment helps regulate (titrate) the patient in a custom tailored manner. The adenosine receptors discussed above are mere examples of the high power of the inventor's technology. In fact, a large number of genes may be targeted in a similar manner by the present agent(s), to reduce or down-regulate protein expression. By means of example, if the target disease or condition is one associated with impeded or reduced breathing, bronchoconstriction, chronic bronchitis, pulmonary bronchoconstriction and/or hypertension, chronic obstructive pulmonary disease (COPD), pulmonary transplantation rejection, pulmonary infections, allergy, asthma, cystic fibrosis, respiratory distress syndrome, cancers, which either directly or by metastasis afflict the lung, the present method may be applied to a list of potential target mRNAs, which includes the targets listed in Table 1 and Table 2 below, among others. The anti-sense agent(s) of the invention have a low A content to prevent its liberation upon in vivo degradation of the agent(s). For example, if the system is the pulmonary or respiratory system, a large number of genes is involved in different functions, including those listed in Table 1 below.

Table 1: Pulmonary and Inflammatory Targets

NFKB Transcription Factor Interleukin-8 Receptor (IL-8 R)

Interleukin-5 Receptor (IL-5R) Interleukin-4 Receptor (IL-4R)

Interleukin-3 Receptor (IL-3R) Interleukin- Iβ (IL-1/3) Interleukin- 1 β Receptor (IL- 1 βR) Eotaxin

Tryptase Major Basic Protein 32-adrenergic Receptor Kinase Endothelin Receptor A

Endothelin Receptor B Preproendothelin

Bradykinin B2 Receptor (B2BR) IgE (High Affinity Receptor) mterleukin-1 (IL-1) Interleukin 1 Receptor (IL-1 R)

Interleukin-9 (IL-9) Interleukin-9 Receptor (IL-9 R)

Interleukin-11 (IL-11) Interleukin- 11 Receptor (IL-11 R)

Inducible Nitric Oxide Synthase Cyclooxygenase (COX)

Intracellular Adhesion Molecule 1 (ICAM-1) Vascular Cellular Adhesion Molecule Substance P (VCAM)

Rantes Endothelial Leukocyte Adhesion Molecule Endothelin ETA Receptor

(ELAM-1)

Cyclooxygenase-2 (COX-2) GM-CSF, Endothelin-1

Monocyte Activating Factor Neutrophil Chemotactic Factor Neutrophil Elastase Defensin 1,2,3

Muscarinic Acetylcholine Receptors Platelet Activating Factor

Tumor Necrosis Factor 5-lipoxygenase

Phosphodiesterase IV Substance P Substance P Receptor Histamine Receptor

Chymase CCR-1 CC Chemokine Receptor

Interleukin-2 (IL-2) Interleukin-4 (IL-4)

Interleukin- 12 (IL-12) Interleukin-5 (IL-5) Interleukin-6 (IL-6) Interleukin-7 (IL-7)

Interleukin-8 (IL-8) hιterleukin-12 Receptor (IL-12R)

Interleukin-7 Receptor (IL-7R) Interleukin- 1 (IL-1)

Interleukin-14 Receptor (IL-14R) Interleukin-14

CCR-2 CC Chemokine Receptor CCR-3 CC Chemokine Receptor CCR-4 CC Chemokine Receptor CCR-5 CC Chemokine Receptor

Prostanoid Receptors GATA-3 Transcription Factor

Neutrophil Adherence Receptor MAP Kinase

Interleukin- 15 (IL-15) Interleukin- 15 Receptor (IL-15R)

Interleukin-l l (IL-l l) Interleukin- 11 Receptor (IL-1 IR) NFAT Transcription Factors STAT 4

MDMα MCP-2

MCP-3 MCP-4

Cyclophillin (A, B, etc.) Phospholipase A2

Basic Fibroblast Growth Factor Metalloproteinase CSBP/p38 MAP Kinase Tryptase Receptor

PDG2 Interleukin-3 (EL-3)

Interleukin- 10 (EL- 10) Cyclosporin A - Binding Protein

FK506-Binding Protein cAβl Selectin

Fibronectin oήβl Selectin cMad CAM-1 LFA-1 (CDl la/CD18)

PECAM-1 LFA-1 Selectin

C3bi PSGL-1

E-Selectin P-Selectin

CD-34 L-Selectin pl50,95 Mac-l (CDllb/CD18)

Fucosyl transferase VLA-4

STAT-1 STAT-2

CD-18/CDl la CD l ib/CD 18

ICAM2 and ICAM3 C5a CCR3 (Eotaxin Receptor) CCR1, CCR2, CCR4, CCR5

LTB-4 AP-1 Transcription Factor

Protein kinase C Cysteinyl Leukoteiene Receptor

Tachykinnen Receptors (tach R) IκB Kinase 1 & 2

Interleukin-2 Receptor (IL-2R) (e.g., Substance P, NK-1 & NK-3 Receptors) STAT 6 c-mas

NF-Interleukin-6 (NF-IL-6) Interleukin- 10 Receptor (IL-1 OR)

Interleukin-3 (IL-3) Interleukin-2 Receptor (IL-2R)

Interleukin-13 (IL-13) Interleukin- 12 Receptor (IL-12R)

Interleukin-14 (IL-14) Interleukin-6 Receptor (IL-6R) Interleukin- 16 (IL-16) Interleukin-13 Receptor (IL-13R)

Medullasin Interleukin- 16 Receptor (IL-16R)

Adenosine Ai Receptor (Ai R) Tryptase-I

Adenosine A_2b Receptor (A_2b R) Adenosine A₃ Receptor (A₃ R) β Tryptase STAT-3 Adenosine A_2a Receptor (A_2a R) IgE Receptor j8 Subunit (IgE R β)

Fc-epsilon receptor CD23 antigen IgE Receptor Subunit (IgE R α)

IgE Receptor Fc Epsilon Receptor (IgERFc ξ R) Substance P Receptor

Histidine decarboxylase Tryptase- 1

Prostaglandin D Synthase Eosinophil Cationic Protein Eosinophil Derived Neurotoxin Eosinophil Peroxidase

Endothelial Nitric Oxide Synthase Endothelial Monocyte Activating Factor

Neutrophil Oxidase Factor Cathepsin G

Macrophage Inflammatory Protein- 1- Interleukin-8 Receptor Subunit (IL-8 Rα)

Alpha/Rantes Receptor Endothelin Receptor ET-B H2A histone family, member N Tubulin, beta polypeptide ELL gene (11-19 lysine-rich leukemia gene) 7-dehydrocholesterol reductase

ADP-ribosylation factor-like 7 Karyopherin alpha 2 (RAG cohort 1, importin alpha 1)

EST (AI038433) EST (AI122689)

EST (AI092623) ESTs (AI095492) ESTs (AI138216) ESTs (AI128305)

ESTs (AI125228) ESTs (AI041482)

ESTs (AI051839) Homo sapiens mRNA; cDNA DKFZp434A1716

ESTs (AI096522) ESTs (AI122807)

ESTs (AI041212) EST (AI125651) Enolase 1, (alpha) EST (AI024215)

EST (AI034360) Homo sapiens mRNA; cDNA DKFZp564H0764

Homo sapiens mRNA for KIAA1363 protein, partial eds

Potassium voltage-gated channel, shaker-related subfamily, beta member 2

ER-associated DNAJ; ER-associated Hsp40 co-chaperone; hDj9; ERj3 ESTs, Weakly similar to p38 protein [H.sapiens] (AA906703)

CGI- 142 ESTs (AA463249)

Homo sapiens clone 25058 mRNA sequence ESTs (R49144)

Squamous cell carcinoma antigen 1 ESTs (AA425700)

Myosin X ESTs (AA459692) Epithelial protein lost in neoplasm beta CD44 antigen (homing function and Indian blood group system)

Coagulation factor III (thromboplastin, tissue factor)

ESTs (AA909635) Adducin 1 (alpha)

5' Nucleotidase (CD73)

ESTs, Moderately similar to semaphorin C [M.musculus] (AA293300) ESTs (AA278764) ESTs (AA678160)

Calmodulin 2 (phosphorylase kinase, delta) ESTs (R42770)

Chloride inttacellular channel 1 High-mobility group (nonhistone chromosomal) protein 17

Ubiquitin carrier protein Tubulin, alpha 1 (testis specific)

Transglutaminase 2 (C polypeptide, prote -glutamine-gamnia-glutamylttansferase) Sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican)

Proteasome (prosome, macropain) 26S subunit, non-ATPase, 2

Tubulin, beta polypeptide Filarnin B, beta (actin-binding protein-278)

Stanniocalcin

Low density lipoprotein receptor (familial hypercholesterolemia) Plectin 1, intermediate filament binding protein, 500kD

SI 00 calcium-binding protein A2 ^' Immediate early response 3

Calpain, large polypeptide L2 Plecksttin homology-like domain, family A, member 1

Melanoma adhesion molecule

CD44 antigen (homing function and Indian blood group system) Programmed cell death 5 Hexokinase 1

Vascular endothelial growth factor Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)

Calurnenin Syntaxin 11

Diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor)

Fnl4 for type I teansmenmbrane protein Nef-associated factor 1 High-mobility group (nonhistone chromosomal) protein isoforms I and Y

Catechol-O-methyltransferase C-terminal binding protein 1

Collagen, type XVII, alpha 1 ESTs (N58473)

Farnesyl-diphosphate farnesylttansferase 1 RNA helicase-related protein

Interferon stimulated gene (20kD) Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)

Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin)

Collagen, type XVII, alpha 1 Keratin 18

Heparan sulfate (glucosamine) 3-O-sulfottansferase 1 Tubulin, alpha 2 Adenylyl cyclase-associated protein

Forkhead box D 1 Cathepsin C

ESTs, Highly similar to AF151802_1 CGI-44 protein [H.sapiens] (T74688)

Ribonucleotide reductase M2 polypeptide

Laminin, gamma 2 (nicein (lOOkD), kalinin (105kD), BM600 (lOOkD), Herlitz junctional epidermolysis bullosa)) Homo sapiens mRNA; cDNA DKFZp586Pl 622 (from clone DKFZp586Pl 622) ESTs, Weakly similar to /prediction (AA284245)

Lactate dehydrogenase A

Note that in the parantheses after "EST(s)" is GENABNK ACESSION NO.

These genes, and others, are involved in the normal functioning of respiration as well as in diseases associated with respiratory pathologies, including cystic fibrosis, asthma, pulmonary hypertension and vasoconsttiction, chronic obstructive pulmonary disease (COPD), pulmonary ttansplantation rejection, pulmonary infections, chronic bronchitis, respiratory distress syndrome (ARDS), allergic rhinitis, lung cancer and lung metastatic cancers and other airway diseases, including those with inflammatory response.

Anti-sense oligos to target receptors, e. g. the adenosine A A_2a, A_2b, and A₃ receptors, CCR3 (chemokine receptors), bradykinin 2B, VCAM (vascular cell adhesion molecule), and eosinophil receptors, among others, have been shown to be effective in down-regulating the expression of their genes. Some of these act to alleviate the symptoms or reduce respiratory ailments and/or inflammation, for example, by "down regulation" of the adenosine Ai, A_2a, A_2b, and/or A₃ receptors and CCR3, bradykinin 2B, VCAM (vascular cell adhesion molecule) and eosinophil receptors. These agents may be utilized by the present method alone or in conjunction with anti-sense oligos targeted to other genes to validate pathway and/or networks in which they are involved. For better results, the oligos are preferably administered directly into the respiratory system, e. g., by inhalation or other means, of the experimental animal, so that they may reach the lungs without widespread systemic dissemination. This permits the use of low agent doses as compared with those administered systemically or by other generalized routes and, consequently, reduces the number and degree of undesirable side effects resulting from the agent's widespread distribution in the body. The agent(s) of this invention has (have) been shown to reduce the amount of receptor protein expressed by the tissue. These agents, thus, rather than merely interacting with their targets, e. g. a receptor, lower the number of target proteins that other drugs may interact with. In this manner, the present agent(s) afford(s) extremely high efficacy with low toxicity. Anti-sense oligonucleotides to the Ai , A_2b, A₃, bradykinin B2, GATA-3, VCAM (vascular cell adhesion molecule), eosinophil receptors, and COX-2 receptors, among others, have been shown to be effective in the down-regulation of the respective receptor proteins in the cell. One novel feature of this freatment, as compared to traditional freatments for adenosine-mediated bronchoconstriction, is that administration is direct to the lungs, or in situ to other tissues, organs or systems of the body. Additionally, a receptor protein itself is reduced in amount, rather than merely interacting with a drug, and toxicity is reduced. Other proteins that may be targeted with anti-sense agents for the freatment of lung conditions include, but are not limited to: CCR3 (chemokine) receptors, human A_2a adenosine receptor, human A_2b adenosine receptor, human IgE receptor β, human

Fc-epsilon receptor CD23 antigen, human histidine decarboxylase, human beta tryptase, human teyptase-I, human prostaglandin D synthase, human cyclooxigenase-2, human eosinophil cationic protein, human eosinophil derived neurotoxin, human eosinophil peroxidase, human intercellular adhesion molecule-1 (ICAM-1), human vascular cell adhesion molecule-1 (VCAM-1), human endothelial leukocyte adhesion molecule-1 (ELAM-1), human P selectin, human endothelial monocyte activating factor, human IL-3, human EL-4, human IL-5, human IL-6, human IL-8, human monocyte-derived neutrophil chemotactic factor, human neutrophil elastase, human neutrophil oxidase factor, human cathepsin G, human defensin 1, human defensin 3, human macrophage inflammatory protein-1-alpha, human muscarinic acetylcholine receptor HM3, human fibronectin, human GM-CSF, human tumor necrosis factor a, human leukotriene C4 synthase, human major basic protein, and human endothelin 1. Although not intended to be exclusive, a more extensive list of genes is provided below. Some of these act to alleviate the symptoms or reduce respiratory ailments and/or inflammation, for example, by "down regulation" of the adenosine A], A_2a, A_2b, and/or A₃ receptors and CCR3, bradyldnin 2B, VCAM (vascular cell adhesion molecule) and eosinophil receptors. These agents are preferably administered directly into the respiratory system, e. g., by inhalation or other means, so that they may reach the lungs without widespread systemic dissemination. This permits the use of substantially lower doses of the agent of the invention as compared with those administered by the prior art, systemically or by other generalized routes and, consequently, reduce undesirable side effects resulting from the agent's widespread distribution in the body. The agent(s) of this invention has (have) been shown to reduce the amount of receptor protein expressed by the tissue. These agents, thus, rather than merely interacting with their targets, e. g. a receptor, lower the number of target proteins that other drugs may interact with. In tiiis manner, the present agent(s) afford(s) extremely high efficacy with low toxicity. In these latter targets, and in target genes in general, it is particularly imperative to eliminate or reduce the adenosine content of the corresponding anti-sense oligonucleotide to prevent their breakdown products from liberating adenosine. As used herein, the term "treat" or "treating" asthma refers to a tteatment which decreases the likelihood that the subject administered such tteatment will manifest symptoms of the lung disease. The term "downregulate" refers to inducing a decrease in production, secretion or availability (and thus a decrease in concentration) of the targeted inttacellular protein. The present invention is concerned primarily with the tteatment of human subjects. However, the agents and methods disclosed here may also be employed for veterinary purposes, such as is the case in the tteatment of other mammals, such as cattle, horses, wild animals, zoo animals, and domestic animals, e. g. dogs and cats. Targeted proteins are preferably mammalian and more preferably of the same species as the subject being treated. In general, "anti-sense" refers to the use of small, synthetic oligonucleotides, resembling single- stranded DNA, to inhibit gene expression by inhibiting the function of the target messenger RNA (mRNA). Milligan, J. F. et al., J. Med. Chem. 36(14), 1923-1937 (1993). In the present invention, inhibition of gene expression of the Ai or A₃ adenosine receptor is desired. Gene expression is inhibited through hybridization to coding (sense) sequences in a specific messenger RNA (mRNA) target by hydrogen bonding according to Watson- Crick base pairing rules. The mechanism of anti-sense inhibition is that the exogenously applied oligonucleotides decrease the mRNA and protein levels of the target gene or cause changes in the growth characteristics or shapes of the cells. Id. See, also Helene, C. and Touhne, J., Biochim. Biophys. Acta 1049, 99-125 (1990); Cohen, J. S. D.,

Ed., Oligodeoxynucleotides as Anti-sense Inhibitors of Gene Expression; CRC Press: Boca Raton, FL (1987). As used herein, "anti-sense oligonucleotide" is defined as a short sequence of synthetic nucleotide that (1) hybridizes to any coding sequence in an mRNA which codes for the targeted protein, according to hybridization conditions described below, and (2) upon hybridization causes a decrease in gene expression of the Ai or A₃ adenosine receptor. The receptors discussed above are mere examples of the high power of the present technology. In fact, a large number of genes may be targeted in a similar manner by practicing the present methods, to significantly down- regulate or obliterate protein expression and observe any changes wrought to one or more functions within a system, e. g. the respiratory system and other lung disease associated targets. By means of example, in the respiratory system, the targets may be associated with difficulties of breathing, bronchoconstriction, inflammation, allergic rhinitis, chronic bronchitis, surfactant depletion, and others associated with diseases and conditions such as chronic obstructive pulmonary disease (COPD), pulmonary transplantation rejection, pulmonary infections, inhalation burns, Acute Respiratory Distress Syndrome (ARDS), cystic fibrosis, pulmonary fibrosis, radiation pulmonitis, tonsilitis, emphysema, dental pain, oral inflammation, joint pain, esophagitis, cancers afflicting the respiratory system either directly such as lung cancer, esophageal cancer, and the like, or indirectly by means of metastases, among others. These functions are of great interest because of their association with respiratory dysfunction, as is the case in asthma, allergies, allergic rhinitis, pulmonary bronchoconstriction and hypertension, chronic obstructive pulmonary disease (COPD), pulmonary transplantation rejection, pulmonary infections, allergy, asthma, cystic fibrosis (CF), Acute Respiratory Distress Syndrome (ARDS) as well as infantile and pregnancy-related RDS, cancer, etc., which either directly or by metastasis afflict the lung, the present anti-sense oligonucleotides may be directed to a list of target mRNAs, which includes the targets listed in Table 1 above, among others.

The first active agent of this invention may be obtained by first selecting fragments of a target nucleic acid having at least 4 contiguous nucleic acids selected from the group consisting of G and C and/or having a specific type and/or extent of activity, and then obtaining a first oligonucleotide 4 to 60 nucleotides long which comprises the selected fragment and has a thymidine (T) or uridine (U) nucleic acid content of up to and including about 15%, preferably, about 12%, about 10%, about 7%, about 5%, about 3%, about 1%, and more preferably no thymidine or uridine. The latter step may be conducted by obtaining a second oligonucleotide 4 to 60 nucleotides long comprising a sequence which is anti-sense to the selected fragment, the second oligonucleotide having an adenosine base content of up to and includήig about 15%, preferably about 12%, about 10%, about 7%, about 5%, about 3%, about 1%, and more preferably no adenosine. When the selected fragment comprises at least one thymidine base, an adenosine base may be substituted in the corresponding anti-sense nucleotide fragment with a universal base selected from the group consisting of heteroaromatic bases which bind to a thymidine base but have less than about bout 10%, preferably less than about 1%, and more preferably less than about 0.3% of the adenosine base agonist activity at the adenosine Ai, A_2a, A_2b and A₃ receptors, and heteroaromatic bases which have no activity at the adenosine A_2a receptor, when validating in the respiratory system. Other adenosine activities in other systems may be deteπriined in other systems, as appropriate. The analogue heteroaromatic bases may be selected from all pyrimidines and purines, which may be substituted by O, halo, NH₂, SH, SO, S0₂, S0₃, COOH and branched and fused primary and secondary amino, alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, alkoxy, alkenoxy, acyl, cycloacyl, arylacyl, alkynoxy, cycloalkoxy, aroyl, arylthio, arylsulfoxyl, halocycloalkyl, alkylcycloalkyl, alkenylcycloalkyl, alkynylcycloalkyl, haloaryl, alkylaryl, alkenylaryl, alkynylaryl, arylalkyl, arylalkenyl, arylalkynyl, arylcycloalkyl, which may be further substituted by O, halo, NH₂, primary, secondary and tertiary amine, SH, SO, S0₂, S0₃, cycloalkyl, heterocycloalkyl and heteroaryl. The pyrimidines and purines may be substituted at all positions as is known in the art, but preferred are those where the purines are substituted at positions 1, 2, 3, 6 and/or 8, and the pyrimidines at positions 2, 3, 4, 5 and/or 6. More preferred are pyrimidines and purines such as those having the chemical formula

PURINES or

PYRIMIDINES wherein R¹ and R² are independently H, alkyl, alkenyl or alkynyl and R³ is H, aryl, dicycloalkyl, dicycloalkenyl, dicycloalkynyl, cycloalkyl, cycloalkenyl, cycloalkynyl, O-cycloalkyl, O-cycloalkenyl, O-cycloalkynyl, NH₂- alkylamino-ketoxyalkyloxy-aryl, or mono or dialkylammoalkyl-N-alkylarnino-S0₂aryl, and R4 and R5 are independently RI and together are R3, and the pyrimidines and purines optionally comprise theophylline, caffeine, dyphylline, etophylline, acephylline piperazine, bamifylline, enprofylline or xantine, among others. Similar modifications in the sugar are also embodiments of this invention. Reduced adenosine content of the anti-sense oligos corresponding to the ymidines (T) present in the target RNA serves to prevent the breakdown of the oligos into products that free adenosine into the system, e. g. the lung, brain, heart, kidney, etc., tissue environment and, thereby, to prevent any unwanted effects due to it. By means of example, the NfkB transcription factor may be selected as a target, and its mRNA or DNA searched for low thymidine (T), uridine (U), desuridine (desU) or desthymidine (desT) fragments. Only desT or desU segments of the DNA or mRNA are selected which, in turn, will produce desA anti-sense as their complementary strand. When a number of DNA or RNA desT or desU segments are found, the sequence of the anti-sense segments may be deduced. Typically, about 10 to 30 and even larger numbers of desA anti-sense sequences may be obtained. These anti-sense sequences may include some or all desA anti-sense oligonucleotide sequences corresponding to desT or desU segments of the mRNA of the target, such as anyone of those shown in Table 1 above, in Table 2 below, and others associated with functions of the brain, cardiovascular and renal systems, and many others. When this occurs, the anti-sense oligonucleotides found are said to be 100% A-free. For each of the original desA anti-sense oligonucleotide sequences corresponding to the target gene, e. g. the NFKB franscription factor, typically about 10 to 30 sequences may be found within the target gene or RNA which have a low content of thymidine (RNA). In accordance with this invention, the selected fragment sequences may also contain a small number of thymidine (DNA) or uridine (RNA) nucleotides within the secondary or tertiary or quaternary sequences. In some cases, a large adenosine content may suffice to render the anti-sense oligonucleotide less active or even inactive against the target. In accordance with this invention, these so called "non-fully desA" sequences may preferably have a content of adenosine of less than about 15%, about 12%, about 10%, about 7%, about 5%, and about 2% adenosine. Most preferred is no adenosine content (0%). In some instances, however, a higher content of adenosine is acceptable and the oligonucleotides still fail to show detrimental "adenosine activity". A particular important embodiment is that where the adenosine nucleotide is

"fixed" or replaced by a "universal or alternative" base that may base-pair with similar or equal affinity to two or more of the four nucleotides present in natural DNA: A, G, C, and T.

A universal or alternative base is defined in this patent as any compound, more commonly an adenosine analogue, which has substantial capacity to hybridize to thymidine, while at the same time having reduced, or substantially lacking, ability to bind adenosine receptors or other molecules through wliich adenosine may exert an undesirable side effect in the experimental animal or in a cell system. Alternatively, adenosine analogs which completely fail to activate, or have significantly reduce ability for activating, adenosine receptors, such as the adenosine A_1; A_2b and/or A₃ receptors, most preferably Ai receptors, and those that may even act as agonists of the adenosine A_2a, receptor, may be used. One example of a universal base is 2'-deoxyribofuranosyl-(5-niteoindole), and an artisan will know how to select others. This "fixing" step generates further novel sequences, different from those anti-sense to the ones found in nature, that permits the anti-sense oligonucleotide to bind, preferably equally well, with the target RNA. Other examples of universal or alternative bases are 2 - deoxyribosyl - (5-nifroindole). Other examples of universal bases are 3 - nifropyrrole - - deoxynucleoside, 5 - nifro-indole, T - deoxyribosyl - (5 - nitroindole), 2'-deoxyribofuranosyl - (5-nitroindole), 2' - deoxyinosine, 2' -deoxynebularine, 6H, 8H-3,4- dihydropyrimido [ 4, 5 - c] oxazine - 7 - one and 2 - amino - 6 -methoxy aminopurine. In addition to the above,

Universal bases which may be substituted for any other base although with somewhat reduced hybridization potential, include 3 - nifropyrrole 2' - deoxynucleoside 2 - deoxyribofuranosyl - (5 - nitroindole), 2' - deoxyinosine and 2' - deoxynebularine (Glen Research, Sterling, VA). More specific mismatch repairs may be made using "P" nucleotide, 6H, 8H - 3, 4 - dihydropyrimido [4,5 - c] [1, 2] oxazin - 7 - one, which base pairs with either guanosine (G) or adenosine (A) and "K" nucleotide, 2 - amino - 6 - memoxyaminopurine, which base pairs with either cytidine

(C) or thymidine (T) and uridine (U), among others. Others that are known in the art or will become available are also suitable. See, for example, Loakes, D. and Brown, D. M., Nucl. Acids Res. 22:4039-4043 (1994); Ohtsuka, E. et al., J. Biol. Chem. 260(5):2605-2608 (1985); Lin, P.K.T. and Brown, D. M., Nucleic Acids Res. 20(19):5149- 5152 (1992; Nichols, R. et al, Nature 369(6480): 492-493 (1994); Rahmon , M. S. and Humayun, N. Z., Mutation Research 377 (2): 263-8 (1997); Amosova, O., et al., Nucleic Acids Res. 25 (10): 1930-1934 (1997); Loakes D. &

Brown, D. M., Nucleic Acids Res. 22 (20): 4039-4043 (1994), the entire sections relating to universal bases and their preparation and use in nucleic acid binding being incorporated herein by reference. When non-fully desT sequences are found in the naturally occurring target, they typically are selected so that about 1 to 3 universal base substitutions will suffice to obtain a 100% "desA" anti-sense oligonucleotide. Thus, the present method provides either anti-sense oligonucleotides to different targets which are low in, or devoid of, A content, as well as anti-sense oligonucleotides where one or more adenosine nucleotides, e. g. about 1 to 3, or more, may be "fixed" by replacement with a "universal" or "replacement" base. Universal bases are known in the art and need not be listed herein in further detail. An artisan will know which bases may act as universal bases, and replace them for A. Table 2 below provides a selected number of targets to which the agents of the invention are effectively applied. Others, however, may also be targeted.

Table 2: Cancer Targets

Transforming Therapy

Oncogenes Targets ras thymidylate synthetase src thymidylate synthetase myc dihydrofolate reductase bcl-2 thymidine kinase deoxycytidine kinase ribonucleotide reductase

Angiogenesis factors Adhesion Molecules

Oncogenes Folate Pathway Enzymes

DNA repair genes (One Carbon Pool)

Telomerase HMG CoA Reductase Farnesyl Transferase Glucose-6-Phosphate Transferase

Akt3 (1-1547)

Ampiregulin (1-1230)) Ap-2 (1-1391)

Ap-2 Beta

Ap-2 Gamma

Sphingomyelinase

Beta-2-Adernergic Receptor , Beta Catenin

E2F-Related Transcription Factor

HM bFGF

B-cell translocation gene 1 (BTG1) cyclin-dependent kinase 2 (CDK2) cyclin-dependent kinase 2 (CDK2) cyclin-dependent kinase 3 (CDK3) cyclin-dependent kinase 4 (CDK4) cyclin-dependent kinase 5 (CDK5) c-ets-1 proto-oncogene checkpoint kinase Chkl (CHK1) type IV collagenase hepatocyte growth factor receptor (c-met)

MYB proto-oncogene protein (MYB)

A group of preferred targets for the treatment of cancer are genes associated with any of different types of cancers or generally known to be associated with malignancies, whether they are regulatory or involved in the production of RNA and/or proteins. Examples are fransforming oncogenes, including, but not limited to, ras, src, myc, and BCL-2, among others. Other targets are those to wliich present cancer chemotherapeutic agents are directed to, such as various enzymes, primarily, although not exclusively, thymidylate synthetase, dihydrofolate reductase, uiyrnidine kinase, deoxycytidine kinase, ribonucleotide reductase, and the like. The present technology is particularly useful in the freatment of cancer ailments given that traditional cancer therapies are fraught with the unresolved problem of selectively killing cancer cells while preserving normal living cells from the devastating effects of treatments such as chemotherapy, radiotherapy, and the like. The present technology provides the ability of selectively attenuating or enhancing a desired pathway or target. This approach provides a significant advantage over standard treatments of cancer because it permits the selection of a pathway, including primary, secondary and possibly tertiary targets, which are not generally expressed simultaneously in normal cells. Thus, the present agent may be administered to a subject to cause a selective increase in toxicity within tumor cells that, for instance, express all three targets while normal cells that may expresses only one or two of the targets will be significantly less affected or even spared. A group of preferred targets for the treatment of cancers are genes associated with different types of cancers, or those generally known to be associated with malignancies, whether they are regulatory or involved in the production of RNA and/or proteins. Examples are transforming oncogenes, including, but not limited to, ras, src, myc, and BCL-2, among others. Other targets are those to which present cancer chemotherapeutic agents are directed to, such as various enzymes, primarily, although not exclusively, thymidylate synthetase, dihydrofolate reductase, thymidine kinase, deoxycytidine kinase, ribonucleotide reductase, and the like.

In one embodiment, at least one of the mRNAs to which the oligo of the invention is targeted encodes a protein such as transcription factors, stimulating and activating factors, inttacellular and extracellular receptors and peptide transmitters in general, interleukins, interleukin receptors, chemokines, chemokine receptors, endogenously produced specific and non-specific enzymes, immunoglobulins, antibody receptors, central nervous system (CNS) and peripheral nervous and non-nervous system receptors, CNS and peripheral nervous and non-nervous system peptide transmitters, adhesion molecules, defensines, growth factors, vasoactive peptides and receptors, and binding proteins, among others; or the mRNA is corresponding to an oncogene and other genes associated with various diseases or conditions. Examples of target proteins are eotaxin, major basic protein, preproendothelin, eosinophil cationic protein, P-selectin, STAT 4, MTP-lα, MCP-2, MCP-3, MCP-4, STAT 6, c-mas, NF-IL-6, cyclophillins, PDG2, cyclosporin A-binding protein, FK5-binding protein, fibronectin, LFA-1 (CDl la/CD18), PECAM-1, C3bi, PSGL-1, CD-34, substance P, pl50,95, Mac-1 (CDl lb/CD18), VLA-4, CD-18/CDl la, CDllb/CD18, C5a, CCR1, CCR2, CCR4, CCR5, and LTB-4, among others. Others are, however, suitable, as well. In another embodiment, at least one of the m NAs to which the oligo is targeted encodes inttacellular and extracellular receptors and peptide transmitters such as sympathoinimetic receptors, parasympathetic receptors, GABA receptors, adenosine receptors, bradyldnin receptors, insulin receptors, glucagon receptors, prostaglandin receptors, thyroid receptors, androgen receptors, anabolic receptors, esttogen receptors, progesterone receptors, receptors associated with the coagulation cascade, adenohypophyseal receptors, adenohypophyseal peptide transmitters, and histamine receptors (HisR), among others. However others are also contemplated. The encoded sympathomimetic receptors and parasympamomimetic receptors include acetylcholinesterase receptors (AcChaseR) acetylcholine receptors (AcChR), ateopine receptors, muscarinic receptors, epinephrine receptors (EpiR), dopamine receptors (DOPAR), and norepinephrine receptors (NEpiR), among others. Further examples of encoded receptors are adenosine Aj receptor, adenosine A_2b receptor, adenosine A₃ receptor, endothelin receptor A, endothelin receptor B, IgE high affinity receptor, muscarinic acetylcholine receptors, substance P receptor, histamine receptor, CCR-1 CC chemokine receptor, CCR-2 CC chemokine receptor, CCR-3 CC chemokine receptor (Eotaxin Receptor), mterleukin-lι3 receptor (IL-lαR), interleukin-1 receptor (IL-1R), interleukin- la receptor (IL-loR), mterleukin-3 receptor (IL-3R), CCR-4 CC chemokine receptor, cysteinyl leukottiene receptors, prostanoid receptors, GATA-3 transcription factor receptor, interleukin-1 receptor (IL-1R), interleukin-4 receptor (IL-4R), interleukin-5 receptor (IL-5R), interleukin-8 receptor (IL-8R), interleukin-9 receptor (IL-9R), interleukin- 11 receptor (IL-11R), sympathomimetic receptors, parasympamomimetic receptors, GABA receptors, adenosine receptors, bradykinin receptors, e. g. bradykinin B2 receptor, insulin receptors, glucagon receptors, prostaglandin receptors, thyroid receptors, androgen receptors, anabolic receptors, esttogen receptors, progesterone receptors, receptors associated with die coagulation cascade, adenohypophyseal receptors, and Mstamine receptors (HisR). Others are also contemplated even though not hsted herein. The encoded enzymes for development of the ohgos of the invention include synthetases, kinases, oxidases, phosphatases, reductases, polysaccharide, triglyceride, and protein hydrolases, esterases, elastases, and , polysaccharide, triglyceride, lipid, and protein synthases, among others.

Examples of target enzymes are tryptase, inducible nitric oxide synthase, cyclooxygenase (Cox), MAP kinase, eosinophil peroxidase, /32-adrenergic receptor kinase, leukottiene c-4 synthase, 5-lipooxygenase, phosphodiesterase IV, metalloproteinase, tryptase, CSBP/ρ38 MAP kinase, neutrophil elastase, phospholipase A₂, cyclooxygenase 2 (Cox- 2), fucosyl transferase, chymase, protein kinase C, thymidylate synthetase, dihydrofolate reductase, thymidine kinase, deoxycytidine kinase, and ribonucleotide reductase, among others. Any enzyme associated with a disease or condition, however, is suitable as a target for this invention. Suitable encoded factors for application of this invention are, among others, NfkB transcription factor, granulocyte macrophage colony stimulating factor (GM- CSF), AP-1 transcription factor, GATA-3 transcription factor, monocyte activating factor, neutrophil chemotactic factor, granulocyte/macrophage colony-stimulating-factor (G-CSF), NFAT transcription factors, platelet activating factor, tumor necrosis factor . (TNF α), and basic fibroblast growth factor (BFGF). Additional factors are also within the invention even though not specifically mentioned. Suitable adhesion molecules for use with this invention include intracellular adhesion molecules 1 (ICAM-1), 2 (ICAM-2) and 3 (ICAM-3), vascular cellular adhesion molecule (VCAM), endothelial leukocyte adhesion molecule-1 (ELAM-1), neutrophil adherence receptor, mad CAM-1, and the like. Other known and unknown factors (at this time) may also be targeted herein. Among the cytokines, lymphokines and chemokines preferred are interleukin-1 (IL-1), terleukin-1 J QL-lβ), interleukin-3 (IL-

3), interleukin-4 (IL-4), interleukin-5 (IL-5), interleukin-8 (IL-8), interleukin-9 (IL-9), interleukin-11 (IL-11), CCR- 5 CC chemokine, and Rantes. Other examples include H2A histone family, member N, Tubulin, beta polypeptide, ELL gene (11-19 lysine-rich leukemia gene) 7-dehydrocholesterol reductase, ADP-ribosylation factor-like 7, Karyopherin alpha 2 (RAG cohort 1, importin alpha 1), EST (AI038433), EST (AI122689), EST (AI092623), ESTs (AI095492), ESTs (AI138216), ESTs (AI128305), ESTs (AI125228), ESTs (AI041482), ESTs (AI051839), Homo sapiens mRNA; cDNA DKFZp434A1716, ESTs (AI096522), ESTs (AI122807), ESTs (AI041212), EST (AI125651), Enolase 1, (alpha), EST (AI024215), EST (AI034360), Homo sapiens mRNA; cDNA DKFZp564H0764, Homo sapiens mRNA for KIAA1363 protein, partial eds, Potassium voltage-gated channel, shaker-related subfamily, beta member 2, ER-associated DNAJ; ER-associated Hsp40 co-chaperone; hDj9; ERj3, ESTs, Weakly similar to p38 protein [H.sapiens] (AA906703), CGI-142, ESTs (AA463249), Homo sapiens clone

25058 mRNA sequence ESTs (R49144), Squamous cell carcinoma antigen 1, ESTs (AA425700), Myosin X, ESTs (AA459692), Epithelial protein lost in neoplasm beta, CD44 antigen (homing function and Indian blood group system), Coagulation factor III (thromboplastin, tissue factor), ESTs (AA909635), Adducin 1 (alpha), 5' Nucleotidase (CD73), ESTs, Moderately similar to semaphorin C [M.musculus] (AA293300), ESTs (AA278764), ESTs (AA678160), Calmodulin 2 (phosphorylase kinase, delta), ESTs (R42770), Chloride intracellular channel 1, High-mobility group (nonhistone chromosomal) protein 17, Ubiquitin carrier protein, Tubulin, alpha 1 (testis specific), Transglutaminase 2 (C polypeptide, protem-glutarnme-gamma-glutamyltransferase), Sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican), Proteasome (prosome, macropain) 26S subunit, non-ATPase, 2, Tubulin, beta polypeptide, Filamin B, beta (actin-binding protein-278), Stanniocalcin, Low density lipoprotein receptor (familial hypercholesterolemia), Plectin 1, intermediate filament binding protein, 500kD, SI 00 calcium- binding protein A2, Immediate early response 3, Calpain, large polypeptide L2, Pleckstrin homology-like domain, family A, member 1, Melanoma adhesion molecule, CD44 antigen (homing function and Indian blood group system), Programmed cell death 5, Hexokinase 1, Vascular endothelial growth factor, Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), Calumenin, Syntaxin 11, Diphtheria toxin receptor (hepar i-binding epidermal growth factor-like growth factor), Fnl4 for type I fransmenmbrane protein, Nef-associated factor 1, High-mobility group (nonhistone chromosomal) protein isoforms I and Y, Catechol-0-methyltransferase, C-teπninal binding protein 1, Collagen, type XVII, alpha 1, ESTs (N58473), Farnesyl-diphosphate farnesylfransferase 1 RNA helicase-related protein, Interferon stimulated gene (20kD), Steroid-5-alρha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1), Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Larriinin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin), Collagen, type XVII, alpha 1, Keratin 18, Heparan sulfate (glucosamine) 3-O-sulfofransferase 1, Tubulin, alpha 2, Adenylyl cyclase-associated protein, Forkhead box Dl, Cathepsin C, ESTs, Highly similar to AF151802_1 CGI-44 protein

[Hsapiens] (T74688), Ribonucleotide reductase M2 polypeptide, Larninin, gamma 2 (nicein (lOOkD), kalinin (105kD), BM600 (lOOkD), Herlitz junctional epidermolysis bullosa)), Homo sapiens mRNA; cDNA DKFZp586P1622 (from clone DKFZp586P1622), ESTs, Weakly similar to /prediction (AA284245), and Lactate dehydrogenase A. Others, however, may also be targeted, as they are known to be involved in specific diseases or conditions to be treated, or for their generic activities, such as inflammation. Examples of defensins for the practice of this invention are defensin 1, defensin 2, and defensin 3, and of selectins are aΛβl selectin, α4 7 selectin, LFA-1 selectin, E-selectin, P-selectin, and L-selectin. Examples of oncogenes, although not an all inclusive list, are ras, src, myc, and bcBCL. Others, however, are also suitable for use with this invention.

The agents administered in accordance with this invention are preferably designed to be anti-sense to target genes and/or mRNAs related in origin to the species to which it is to be administered. When treating humans, the agents are preferably designed to be anti-sense to a human gene or RNA. The agents of the invention encompass oligonucleotides which are anti-sense to naturally occurring DNA and or RNA sequences, fragments thereof of up to a length of one (1) base less than the targeted sequence, preferably at least about 7 nucleotides long, oligos having only over about 0.02%, more preferably over about 0.1%, still more preferably over about 1%, and even more preferably over about 4% adenosine nucleotides, and up to about 30%, more preferably up to about 15%, still more preferably up to about 10% and even more preferably up to about 5%, adenosine nucleotide, or lacking adenosine altogether, and oligos in which one or more of the adenosine nucleotides have been replaced with so-called universal bases, which may pair up with thyrnidine nucleotides but fail to substantially trigger adenosine receptor activity. Examples of human sequences and fragments, which are not limiting, of anti-sense oligonucleotide of the invention are the following fragments as well as shorter segments of the fragments and of the full gene or mRNA coding sequences, exons and intron-exon junctions encompassing preferably 7, 10, 15, 18 to 21, 24, 27, 30, n-1 nucleotides for each sequence, where n is the sequence's total number of nucleotides. These fragments may be selected from any portion of the longer oligo, for example, from the middle, 5'- end, 3'- end or starting at any other site of the original sequence. Of particular importance are fragments of low adenosine nucleotide content, that is, those fragments containing less than or about 30%, preferably less than or about 15%, more preferably less than or about

10%, and even more preferably less than or about 5%, and most preferably those devoid of adenosine nucleotide, either by choice or by replacement with a universal base in accordance with this invention. The agent of the invention includes as a most preferred group sequences and their fragments where one or more adenosines present in the sequence have been replaced by a universal base (B), as exemplified here. Similarly, also encompassed are all shorter fragments of the B-containing fragments designed by substitution of B(s) for adenosine(s) (A(s)) contained in the sequences, fragments thereof or segments thereof, as described above. A limited list of sequences and fragments is provided below. Some of the examples of anti-sense oligonucleotide sequence fragments target the initiation codon of the respective gene, and in some cases adenosine is substituted with a universal or alternative base adenosine analogue denoted as "B", wliich lacks ability to bind to the adenosine Ai and/or A₃ receptors. In fact, such replacement nucleotide acts as a "spacer". Many of the examples shown below provide one such sequence and many fragments overlapping the initiation codon, preferably wherein the number of nucleotides n is about 7, about 10, about 12, about 15, about 18, about 21 and up to about 28, about 35, about 40, about 50, about 60.

Human Receptor-related Antisense Polynucleotide

5'-GGCGGCCTGG AAAGCTGAGA TGGAGGGCGG CATGGCGGGC ACAGGCTGGG C TGCTTTTCT TTTCTGGGCC TCTGTGGTCT GTTTTTTTCT GGCCCTGCTG GGGCGCTCTC CGCCGCCCGC CTGGCTCCCG GBGCCCBTGB TGGGCBTGCC GTGGTTCTTG CCCTCCTTTG GCTGCCGTGC CCGCTCCCCG GCCTCCTGGC GGGTGGCCGT TGGGCCCGTG TTCCCCTGGG GCCTGGGGCT CCCTTCTCTC GCCCTTCTTG CTGGGCCTCT GCTGCTGCTG GTGCTGTGGC CCCCGTACA CCGAGGAGCC CATGATGGGC

ATGCCACAGA CGACAGGCGT BCBCCGBGGB GCCCBTGBTG GGCBTGCCBC BGBCGBCBGG C GGC GCC GTG CCG CGT CTT GGT GGC GGC GG GTT CGC GCC CGC GCG GGG CCC CTC CGG TCC GTT CGC GCC CGC GCG GGG CCC CTC CGG TCC CGG GTC GGG GCC CCC CGC GGC C GCC TCG GGG CTG GGG CGC TGG TGG CCG GG CCG CGC CTC CGC CTG CCG CTT CTG GCT GGG CCC CGG GCG CCC CCT CCC CTC TTG CTC GGG TCC CCG TG ACA GCG CGT CCT GTG TCT CCA GCA GCA TGG CCG GGC CAG CTG GGC CCC BCB GCG CGT CCT GTG TCT CCB GCB GCB TGG CCG GGC CBG CTG GGC CCC ACA GAG CAG TGC TGT TGT TGG GCA TCT TGC CTT CCC AGG G BCB GBG CB TGC TGT TGT TGG GCB TCT TGC CTT CCC BGG GCC CTT TTC TGG TGG GGT GGT GCT GTT GTT GGG CTT TCT TCT GTT CCC BCB GBG CBG TGC TGT

TGT TGG GCB TCT TGC CTT CCC BGG GCC CTT TTC TGG TGG GGT GGT GCT GTT GTT GGG C TTT CTT CTG TTC CC TTT CCC CTG GGT CTT CC CTC CTG CTC TTT TTT C ATT TGC TCT CCT ATT ACT TTC TGT GTC CAT TTT TTC ATT AAC CGA GCT GT BTT TGC TCT CCT BTT BCT TTC TGT GTC CBT TTT TTC BTT BBC CGB GCT GT GCC TGT GTC TGT CCT CCT GCT TCG TTC CTC TCG TTC CTG CTT GGT GCC CTT GCC G GTC CTG CTC CTC CGG GCT GTG G GTC GTG GCC CTG GCT CCG GCT GGT GGG CTC CCC TGG CCT TCG CTG GCT GGC GGC GTG C GGG TCT TGC TCT GGG CCT GGC TGT GGC CGT GGT TGG GGG TCT TC GCT GCC TCC GTT TGG GTG GC TCT CTG AAT ATT GAC CTT CCT CCA TGG CGG TCC TGC TTG GAT TCT CCC GA TCT CTG BBT BTT GBC CTT CCT CCB TGG CGG TCC TGC TTG GBT TCT CCC GB GCC

TTT CCT GGT TCT CTT GTT GTT TTT GGG GTT TGG CTT ACA GTA GAG TAG GGG ATT CCA TGG CAG GAG CCA TCT TCT TCA TGG ACT CC TTC AAG GAG ACC TTA GGT TTC TGA GGG ACT GCT AAC ACG CCA TCT GGA GC BCB GTB GBG TBG GGG BTT CCB TGG CBG GBG CCB TCT TCT TCB TGG BCT CC TTC BBG GBG BCC TTB GGT TTC TGB GGG BCT GCT BBC BCG CCB TCT GGB GC GTT GTT TTT GGG GTT TGG CTT GCC TTT CCT GGT TCT CTT BCB GTB GBG TBG GGG BTT CCB TGG CBG GBG CCB TCT TCT TCB TGG BCT CC TTC BBG GBG BCC TTB GGT TTC TGB GGG BCT GCT BBC BCG CCB TCT GGB GC GCC TGT GTC TGT CCT CCT GCT TCG TTC CTC TCG TTC CTG CTT GGT GCC CTT GCC G GTC CTG CTC CTC CGG GCT GTG G GTC CTC GCC CTG GCT CCG GCT GGT GGG CTC CCC TGG CCT TCG CTG GCT GGC GGC

GTG C CCC BGB BCG BGB CCC GGB CCG BCB GGC CGT GGT TGG GGG TCT TC GCT GCC TCC GTT TGG GTG GC GAT CTC TGA ATA TTGA CCT TCC ATG GCG GTC CTG CTT GGA GBT CTC TGB BTB TTGB CCT TCC BTG GCG GTC CTG CTT GGB TCT GGG GTG TCC TGG CCT TCG TGG TTC CTC TTC CTT CGT TTG CCG TCC GCG GGG GCC CCC GGG CCT GGC TGC GCT CCT GCC CCG CCT CTT TCC CGG GCT CTT GCG CTG GGG GGT GCT CC CGT GTG TTT GCG CCC TC CTC CTG GTC GCG CTT GTC GTT TTG GGG CCG GCT TTG CCC GCC TCC CGG CGC CTG GCC CGG CC TTC CTG GGC TGC GTG CGC GTT CTG TTC TTC TTC CTG GCT CTG GGG TGT CCT GGC CTT CGT GGT TCC TCT TCC TTC GTT TGC CGT CCG CGG GGG CCC CCG GGC CT GGC TGC GCT CCT GCC CCG CCT CTT TCC CGG GCT CTT GCG CTG GGG GGT GCT CCC

GTG TGT TTG CGC CCT CCT CCT GGT CGC GCT TGT CGT TTT GG GGC CGG CTT TGC CCG CCT CCC GGC GCC TGG CCC GGC CTT CCT GGG CTG CGT GCG CGT TCT GTT CTT CTT CCT GGC GCA GGA GAC AGG GCA GGG CGA TCA GGA GCA GCG TGA GCC AAA GGA GGA CCA TCG GGA ACG CAG CTC CGG AAC GCA GGA CAG AGG TGC C GC BGG BGB CBG GGC BGG GCG BTC BGG BGC BGC GTG BGC CBB BGG BGG BCC BTC GGG BBC GCB GCT CCG GBB CGC BGG BCB GBG GTG CC TCT GCC CTG TCC GCC GGC TCT TCG GTG GCT CGG CCC CGC TCC TTG TCT TGC CGC GGG TTG GTT CCT GGG CCT GGT TCT TGC GGG CGT TTC GGT CTG CTG GCT GGT CTG GGC CCG CGG TGC GGC GGG TGG CTT GCT GTT CTG CCT GGG CTC TCC CCT CTC CTC CTT TTC TCC CTT CCT CTG TCT TGC CTC CTT CCT CTG GGT CCT CTT GGC

CTG GGC GCT CTT CCC CTC GGG CGG CTG CGG GCG CTC GTG CTG CCT GGT CCG CTC CCT GGG GGT GCT CCT TCC CTT TCC CCG CTC GTG GGG TTT GCG GGG CTG GGC TGC CCT GGG GGG TCT GGG CCT TTT GGG GTC GGC TGG CTG CTG CTT CGG GCC GCC TGG GCT TCC CTG TGC CCC TTT CCT CTG CTG GGT CCC CCT CCC GTT CCA AGC TGC ACC GCA CAG ACC GGC GCT ACA GGA CAG AGC CAG GCA AGC ACC CAT GGG GAT CCA GGC CCA GCT GTT CCB BGC TGC BCC GCB CBG BCC GGC GCT BCB GGB CBG BGC CBG GCB BGC BCC CBT GGG GBT CCB GGC CCB GCT G CTCAGTGGCC CCCAAAAGGA TGAGTAATAC ATGCGOCACG ATGATCATAT CCTTTTTACT ATGAGGCCGT GTCTGTCGTG TCTTTCCTTT GCTCTTGGTG TGTCTTTGCT GTGCCCTGCC TCTCTGCCCG TGTCTGTCGT GTCTTTCCTT TGCTCTTGGT

GTGTCTTTGC TGTGCCCTGC CTCTCTGCC CGTGTCTGTC GTGTCTTTCC TTTGCTCTTG GTGTGTCTTT GCTGTGCCCT GCCTCTCTGC GGGGGTGGCT TCCTGCCGCG TCTCTGGGCC GTCCCGTCCC TCGGCCCCGC GCCGCGCTCG GCTCCTCTCC CTCTGGCCCG GCTCGGGGCG GGGCGGGGCG GTGGGCGGGC GGCGCTGCCC TGCGCGCGGC GCTGGCCCCT GCTGGCCGTC GGCTGCGCGC TGCTGGCTGC CCTGCTGGCC GCGCCGGGGC CTGTCCGCCT CTGCGGGCGC TGTCTCCTGG CTTGTCTTCC GGCTCTTCTG CTGGGGTGGG GCTGGGCGGC CGGCCCGGTG CTGGGGCTCC TCGGGGGGGG GGGCTCTTCC GGGCTGTCTC CCTCCGGGGC GGGGGTTTCT GGCCGTGGGG GTCTTGCCTG GCCTCCGGGC TCCTGCTTGT CTTGCCTTCC TTCTCTGGTC GGTTGTGGCT CGGGGCTCCG TGGGTCCCTG GCGCCCGTTT GTGTTTTGTC TTTTCCCCTG GCGTCCCTGT

GCCCCTCTCC TCTCCTTCCT CTGCTTCTCG CTCTCCTTTG TGGGGCCCTC CCTGCTGCTC TTGGTTTTGG GCTTTTTTTC TCTTCCTCCT TTTTCGTGCG TGGGCCTCC GCACGCCTCT TGCCACCTCC TGCGCAGGGC AGCGCCTTGG GGCCAGCGCC GCTCCCGGCG CGGCCAGCAG GGCAGCCAGC AGCGCGCAGC CGACGGCCAG CATGCTTCCT CCTCGGCTAC CACTCCATGG TCCCGCAGAG GCGGACAGGC GCBCGCCTC TTGCCBCCTC CTGCGCBGGG CBGCGCCTTG GGGCCBGCGC CGCTCCCGGC GCGGCCBGCB GGGCBGCCBG CBGCGCGCBG CCGBCGGCCB GCBTGCTTCC TCCTCGGCTB CCBCTCCBTG GTCCCGCBGB GGCGGBCBGG C GCTGCCCGGC GGGGTGTGCG CTTGGCGCTC CCGTGCTCGG TTCTCTGTCT CCCGGTCCCC CTTGCCTGGC GTCTCGGGCC TTCGTCCTCT TCCTCTTCTT CCTTCCGCTC CGTGGGGGCT GCTTGGTGGG

GGCCTGTGCCT CGGGGTCCCG GGGCTTCTGG CCCTTGCCGT TCATGGTGGC TAGGTGGGGC GTTCBTGGTG GCTBGGTGGG GC GGG GTG GGT BGG CCG TGT CTG GGGGTT GGC CBT GTT GGT TGC CTCT TGG TGG TGC GCC GGG CGCG TCT TGG CTT TCT TCT CCT TCG GGC CCT CGG GCC GGT GCT TGT GGGCT CCT CCC GGG CGG CCT CCC CGG GCG GGG GCT TCT TGGCG CTG GCG GGG GGG CCT CCTGCT CTG TGG CTG GGC GTT CCT TGG TGT TCT GGG TGGTGG CGG GCG TGG TGG CCT CTG TGGGGG CCC GCG GCT GCB GGG GTTG CCT GTC TGC TTC GTCCTT TGC GCT CCC GGG CCG CCGGG GTG GGT AGG CCG TGT CTG GGGGTT GGC CAT GTT GGT TGC CGGG CCC GCG GCT GCA GGG G ACAGGGGCTG TAATCTTCATC TGCAGGTGGC ATGCCAGTGA AATTTAGATC ATCAAAATCC CACATCTGTG GATCTGTAAT

ATTTGACATG TCCTCTTCAG TTTCAGCAAT GGTTTGATCT AACTGAAGCA CCGGCCAGGB CBGGGGCTGT BBTCTTCBTC TGCBGGTGGC BTGCCBGTGB BBTTTBGBTC BTCBBBBTCC CBCBTCTGTG GBTCTGTBBT BTTTGBCBTG TCCTCTTCBG TTTCBGCBB TGGTTTGBTC TBBCTGBBGC BCCGGCCBGG TGGCTCGGTG CTTCTGCCCC TGTTGTTGCG GCGCTCGGTT GGTGTGGCCC CTGTGGTGCT TCGTTTCCCC CTCTTTCTCT TTGTTCGGGG GTTCTTGTGG CGGGCTGCTT GTCTCGTTCC GCCCTGTCGG GCGGGAAGCC TCTCTCCTCT CCCCAGATC CGCGACAGGC CGCAGGCAAG AACCAGCGCA ACCAGGGCGC GTCCGCACAG ACTTGGAGGC GGCTGCATGC TGCTACCTGC TCCAGAAGCG TCCGGTGGCC GCCGCGCC CTGTCGGGCG GGBBGCCTCT CTCCTCTCCC CBGBTCCGCG BCBGGCCGCB GGCBBGBBCC BGCGCBBCCB GGGCGCGTCC

GCBCBGBCTT GGBGGCGGCT GCBTGCTGCT BCCTGCTCGGGCG GGBBGCCTCCG GTGGCCGCCG CGCGTCCGGT GGCCGCCGCG CCTCTCTCCT CTCCCCGTGG CCCTGTCGGG CGGGTCCTGC CGTCCTGTCT CCTTTTCTTT TGCTGTCTTG TCTTCCCGTC TCTGCTTT GTCTGTCCTC CCCGTCTCCT CCCACTGCTT CTCCCGGGGG CTTCCCCGGC TTCGGGTGGC CGGTGTCCCG GGCTCCGGCG CGGCGGCGGC TTCGGCTGCG GGTGGGTGGC GCGGGCTGCC GGGTCCGCGC GGCGCCTGGG CCCTTGTGCT GCTTTTTGCT TGTTCCGTTC TGGCTGCTCC GGTCTGTGTT GTGGTTGTTT TGTTTCTTCT TGGGTGTGGG CCTTGCGGTT TTGGCTGTGG GCCCTTTGGG GCCTTGGCTT CTGGCTCGTC TGTCCTCCCC GTCTCCTCCC ACTGCTTCT CCCGGGGGCT TCCCCGGCTT CGGGTGGCCG GTGTCCCGGG CTCCGGCGCG GCGGCGGCTT CGGCTGCGGG

TGGGTGGCGC GGGCTGCCGG GTCCGCGCGG CGCCTGGGCC CTTGTGCTGC TTTTTGCTTG TTCCGTTCTG GCTGCTCCGG TCTGTGTTGT GGTTGTTTTG TTTCTTCTTG GGTGTGGGCC TTGCGGTTTT GGCTGTGGGC CCTTTGGGGC CTTGGCTTCT GGCTCCAT CCACATGATT GCTTAGATTT GTGCTGTATC TCTCAGGATT ATCACTGATT ACACATCCAA CCAGTGCCAG CCAAAAGGAT GCCCTGAGGC AAAGGGTTTC CATCTTGAGG CAAATTTGAG GACBTCCBC BTGBTTGCTT BGBTTTGTGC TGTBTCTCTC BGGBTTBTCB CTGBTTBCBC BTCCBBCCBG TGCCBGCCBB BBGGBTGCCC TGBGGCBBBG GGTTTCCBTC TTGBGGCBBB TTTGBGGBGGGCTBBGBT GBTCCBCBTC BCTBCCBCGT TGCCCBCCBC BGBGGTCBCC BCBBTGBCCG TGTBGGCBGC TGCCCBBBGG BCBBTTTGCC BGGCTGGTTG CBCGBBCTGB TTGGGTTCCG BGGTGTTBGT

GGBGBTGTTT GGGGBGBGGT CTGBGTCCBC CGGGBGGBCG TTBTCCBTTT CGBBGCTBGG CGGTBBBGCC CTBCTBTCTG TBCBCBBCCC CCCTCTGCBG CBGBGTCCTG TCGTGGCGCC TGGGGCTCBG GGTCCGGGC TAAGATGATC CACATCACTA CCACGTTGCC CACCACAGAG GTCACCACAA TGACCGTGTA GGCAGCTGCC CAAAGGACAA TTTGCCAGGC TGGTTGCACG AACTGATTGG GTTCCGAGGT GTTAGTGGAG ATGTTTGGGG AGAGGTCTGA GTCCACCGGG AGGACGTTAT CCATTTCGAA GCTAGGCGGT AAAGCCCTAC TATCTGTACA CAACCCCCCT CTGCAGCAGA GTCCTGTCGT GGCGCCTGGG GCTCAGGGTC CGTCCTGTCG TGGCGCCTGG GGCTCTTCTT TTGTGGGCTC TTTGGTGGCT GTGGCTGTGG TCTCTGTGGT TGCTGCCCTG GGTCTGGGGG TGTGGCCTTG GGGCCGTCCT CTGGCTCCTC CTCGTGGGCC CCC GGTGBCBTTG

BGCBTGTCGG CGCGGTCCCG TTBBGBGTGG GCCCGCCAGC CCAGCCACTC CACTTGGGGG CGGGTGGCCA GCACGAACAG CACCCAGAGG AAGGGGGGCG GCCCAGAAGG GCAGCCCGCA GGCCAGGATC AGGTCTGCTG CGGCCGGAGA TAATGGCATT CACCACGCGG CGGCCCAGCG CACGCCGCGC ATCCGGCCCG GGTTCTGACC TGCAGCCCCC GTCTCCTTGG CATTCCTGGG CCCCAGTCAC TCCTCTCCCT GCCCCCCTTG CTGGGGCAGG GACGGGGTG BCBTTGBGCB TGTCGGCGCG GTCCCGTTBB GBGTGGGCCC GCCAGCCCAG CCACTCCACT TGGGGGCGGG TGGCCAGCAC GAACAGCACC CAGAGGAAGG GGGGCGGCCC AGAAGGGCAG CCCGCAGGCC AGGATCAGGT CTGCTGCGGC CGGAGATAAT GGCATTCACC ACGCGGCGGC CCAGCGCACG CCGCGCATCC GGCCCGGGTT CTGACCTGCA GCCCCCGTCT

CCTTGGCATT CCTGGGCCCC AGTCACTCCT CTCCCTGCCC CCCTTGCTGG GGCAGGGACG GCCGTGTTGT CBGTGGTGCT GCCCGTTTGB GGTBTGGCGC TCCBCCBBTT CCCTTTTCTC CTTGTTTTCC GTTTCTCTTG CCGTCTGTGG TT ATGCCGCCCT CCATCTCAGC TTTCCAGGCC GCCTACATCG GCATCGAGGT GCTCATCGCC CTGGTCTCTG TGCCCGGGAA CGTGCTGGTG ATCTGOGCGG TGAAGGTGAA CCAGGCGCTG CGGGATGCCA CCTTCTGCTT CATCGTCTCG CTGGCGGTGG CTGATGTGGC CGTGGGTGCC CTGGTCATCC CCCTCGCCAT CCTCATCAAC ATTGGGCCAC AGACCTACTT CCACACCTGC CTCATGGTTG CCTGTCCGGT CCTCATCCTC ACCCAGAGCT CCATCCTGGC CCTGCTGGCA ATTGCTGTGG ACCGCTACCT CCGGGTCAAG ATCCCTCTCC GGTACAAGAT GGTGGTGACC CCCCGGAGGG CGGCGGTGGC CATAGCCGGC TGCTGGATCC

TCTCCTTCGT GGTGGGACTG CCCCTATGT TTGGCTGGAA CAATCTGAGT GCGGTGGAGC GGGCCTGGGC AGCCAACGGC AGCATGGGGG AGCCCGTGAT CAAGTGCGAG TTCGAGAAGG TCATCAGCAT GGAGTACATG GTCTACTTCA ACTTCTTTGT GTGGGTGCTG CCCCCGCTTC TCCTCATGGT CCTCATCTAC CTGGAGGTCT TCTACCTAAT CCGCAAGCAG CTCAACAAGA AGGTGTCGGC CTCCTCCGGC GACCCGCAGA AGTACTATGG GAAGGAGCTG AAGATCGCCA AGTCGCTGGC CCTCATCCTC TTCCTCTTTG CCCTCAGCTG GCTGCCTTTG CACATCCTCA ACTGCATCAC CCTCTTCTGC CCGTCCTGCC ACAAGCCCAG CATCCTTACC TACATTGCCA TCTTCCTCAC GCACGGCAAC TCGGCCATGA ACCCCATTGT CTATGCCTTC CGCATCCAGA AGTTCCGCGT CACCTTCCTT AAGATTTGGA ATGACCATTT CCGCTGCCAG CCTGCACCTC CCATTGACGA

GGATCTCCCA GAAGAGAGGC CTGATGACTA G ATGAGTGTCA GAAGTGTGAA GGGTGCCTGT TCTGAATCCC AGAGCCTCCT CTCCCTCTGT GAGGCTGGCA GGTGAGGAAG GGTTTAACCT CACTGGAAGG AATCCCTGGA GCTAGCGGCT GCTGAAGGCG TCGAGGTGTG GGGGCACTTG GACAGAACAG TCAGGCAGCC GGGAGCTCTG CCAGCTTTGG TGACCTTGGG CCGGGCTGGG AGCGCTGCGG CGGGAGCCGG AGGACTATGA GCTGCCGCGC GTTGTCCAGA GCCCAGCCCA GCCCTACGCG CGCGGCCCGG AGCTCTGTTC CCTGGAACTT TGGGCACTGC CTCTGGGACC CCTGCCGGCC AGCAGGCAGG ATGGTGCTTG CCTCGTGCCC CTTGGTGCCC GTCTGCTGAT GTGCCCAGCC TGTGCCCGCC ATGCCGCCCT CCATCTCAGC TTTCCAGGCC GCCTACATCG GCATCGAGGT GCTCATCGCC CTGGTCTCTG TGCCCGGGAA CGTGCTGGTG ATCTGGGCGG TGAAGGTGAA CCAGGCGCTG CGGGATGCCA CCTTCTGCTT CATCGTGTCG CTGGCGGTGG CTGATGTGGC CGTGGGTGCC CTGGTCATCC CCCTCGCCAT CCTCATCAAC ATTGGGCCAC AGACCTACTT CCACACCTGC CTCATGGTTG CCTGTCCGGT CCTCATCCTC ACCCAGAGCT CCATCCTGGC CCTGCTGGCA ATTGCTGTGG ACCGCTACCT CCGGGTCAAG ATCCCTCTCC GGTACAAGAT GGTGGTGACC CCCCGGAGGG CGGCGGTGGC CATAGCCGGC TGCTGGATCC TCTCCTTCGT

GGTGGGACTG ACCCCTATGT TTGGCTGGAA CAATCTGAGT GCGGTGGAGC GGGCCTGGGC AGCCAACGGC AGCATGGGGG AGCCCGTGAT CAAGTGCGAG TTCGAGAAGG TCATCAGCAT GGAGTACATG GTCTACTTCA ACTTCTTTGT GTGGGTGCTG CCCCCGCTTC TCCTCATGGT CCTCATCTAC CTGGAGGTCT TCTACCTAAT CCGCAAGCAG CTCAACAAGA AGGTGTCGGC CTCCTCCGGC GACCCGCAGA AGTACTATGG GAAGGAGCTG AAGATCGCCA AGTCGCTGGC CCTCATCCTC TTCCTCTTTG CCCTCAGCTG GCTGCCTTTG CACATCCTCA ACTGCATCAC CCTCTTCTGC CCGTCCTGCC ACAAGCCCAG CATCCTTACC TACATTGCCA TCTTCCTCAC GCACGGCAAC TCGGCCATGA ACCCCATTGT CTATGCCTTC CGCATCCAGA AGTTCCGCGT CACCTTCCTT AAGATTTGGA ATGACCATTT CCGCTGCCAG CCTGCACCTC CCATTGACGA

GGATCTCCCA GAAGAGAGGC CTGATGACTA GACCCCGCCT TCCGCTCCCA CCAGCCCACA TCCAGTGGGG TCTCAGTCCA GTCCTCACAT GCCCGCTGTC CCAGGGGTCT CCCTGAGCCT GCCCCAGCTG GGCTGTTGGC TGGGGGCATG GGGGAGGCTC TGAAGAGATA CCCACAGAGT GTGGTCCCTC CACTAGGAGT TAACTACCCT ACACCTCTGG GCCCTGCAGG AGGCCTGGGA GGGCAAGGGT CCTACGGAGG GACCAGGTGT CTAGAGGCAA CAGTGTTCTG AGCCCCCACC TGCCTGACCA TCCCATGAGC AGTCCAGCGC TTCAGGGCTG GGCAGGTCCT GGGGAGGCTG AGACTGCAGA GGAGCCACCT GGGCTGGGAG AAGGTGCTTG GGCTTCTGCG GTGAGGCAGG GGAGTCTGCT TGTCTTAGAT GTTGGTGGTG CAGCCCCAGG ACCAAGCTTA AGGAGAGGAG AGCATCTGCT CTGAGACGGA TGGAAGGAGA GAGGTTGAGG

ATGCACTGGC CTGTTCTGTA GGAGAGACTG GCCAGAGGCA GCTAAGGGGC AGGAATCAAG GAGCCTCCGT TCCCACCTCT GAGGACTCTG GACCCCAGGC CATACCAGGT GCTAGGGTGC CTGCTCTCCT TGCCCTGGGC CAGCCCAGGA TTGTACGTGG GAGAGGCAGA AAGGGTAGGT TCAGTAATCA TTTCTGATGA TTTGCTGGAG TGCTGGCTCC ACGCCCTGGG (JAGTGAGCTT GGTGCGGTAG GTGCTGGCCT CAAACAGCCA CGAGGTGGTA GCTCTGAGCC CTCCTTCTTG CCCTGAGCTT TCCGGGGAGG AGCCTGGAGT GTAATTACCT GTCATCTGGG CCACCAGCTC CACTGGCCCC CGTTGCCGGG CCTGGACTGT CCTAGGTGAC CCCATCTCTG CTGCTTCTGG GCCTGATGGA GAGGAGAACA CTAGACATGC CAACTCGGGA GCATTCTGCC TGCCTGGGAA CGGGGTGGAC GAGGGAGTGT CTGTAAGGAC TCAGTGTTGA CTGTAGGCGC CCCTGGGGTG GGTTTAGCAG

GCTGCAGCAG GCAGAGGAGG AGTACCCCCC TGAGAGCATG TGGGGGAAGG CCTTGCTGTC ATGTGAATCC CTCAATACCC CTAGTATCTG GCTGGGTTTT CAGGGGCTTT GGAAGCTCTG TTGCAGGTGT CCGGGGGTCT AGGACTTTAG GGATCTGGGA TCTGGGGAAG GACCAACCCA TGCCCTGCCA AGCCTGGAGC CCCTGTGTTG GGGGGCAAGG TGGGGGAGCC TGGAGCCCCT GTGTGGGAGG GCGAGGCGGG GGAGCCTGGA GCCCCTGTGT GGGAGGGCGA GGCGGGGGAT CCTGGAGCCC CTGTGTCGGG GGGCGAGGGA GGGGAGGTGG CCGTCGGTTG ACCTTCTGAA CATGAGTGTC AACTCCAGGA CTTGCTTCCA AGCCCTTCCC TCTGTTGGAA ATTGGGTGTG CCCTGGCTCC CAAGGGAGGC CCATGTGACT AATAAAAAAC TGTGAACCCT CGCATTTGTG TTTTAATAAA AGAATCTGGA AGATAAATAG TCTTGAAGAG

AGACAAAGGA AGGAAAATTT AAATCCTTAG ATTCAAGCAG AAGAATTGCA TGTGGAAGGT TTGGGTTGTT GTTGTTGTTG TTTGGTGTGT TTTTTGTTTT TTTGTTTTTT TGTTTTTTTT TGAGATGGAG TCTCGCTGTG TTACCGGGAG CGACAGAGCC GCACGGCCGA GTCGAGTCCC AGCCAGCTAC CATCCCTCTG GAGCTTACCG GCCGGCCTTG GCTTCCCCAG GAATCCCTGG AGCTAGCGGC TGCTGAAGGC GTCGAGGTGT GGGGGCACTT GGACAGAACA GTCAGGCAGC CGGGAGCTCT GCCAGCTTTG GTGACCTTGG GTGCTTGCCT CGTGCCCCTT GGTGCCCGTC TGCTGATGTG CCCAGCCTGT GCCCGCCATG CCGCCCTCCA TCTCAGCTTT CCAGGCCGCC TACATCGGCA TCGAGGTGCT CATCGCCCTG GTCTCTGTGC CCGGGAACGT GCTGGTGATC TGGGCGGTGA AGGTGAACCA GGCGCTGCGG GATGCCACCT TCTGCTTCAT CGTGTCGCTG GCGGTGGCTG

ATGTGGCCGT GGGTGCCCTG GTCATCCCCC TCGCCATCCT CATCAACATT GGGCCACAGA CCTACTTCCA CACCTGCCTC ATGGTTGCCT GTCCGGTCCT CATCCTCACC CAGAGCTCCA TCCTGGCCCT GCTGGCAATT GCTGTGGACC GCTACCTCCG GGTCAAGATC CCTCTCCGGT ACAAGATGGT GGTGACCCCC CGGAGGGCGG CGGTGGCCAT AGCCGGCTGC TGGATCCTCT CCTTCGTGGT GGGACTGACC CCTATGTTTG GCTGGAACAA TCTGAGTGCG GTGGAGCGGG CCTGGGCAGC CAACGGCAGC ATGGGGGAGC CCGTGATCAA GTGCGAGTTC GAGAAGGTCA TCAGCATGGA GTACATGGTC TACTTCAACT TCTTTGTGTG GGTGCTGCCC CCGCTTCTCC TCATGGTCCT CATCTACCTG GAGGTCTTCT ACCTAATCCG CAAGCAGCTC AACAAGAAGG TGTCGGCCTC CTCCGGCGAC CCGCAGAAGT ACTATGGGAA GGAGCTGAAG ATCGCCAAGT CGCTGGCCCT

CATCCTCTTC CTCTTTGCCC TCAGCTGGCT GCCTTTGCAC ATCCTCAACT GCATCACCCT CTTCTGCCCG TCCTGCCACA AGCCCAGCAT CCTTACCTAC ATTGCCATCT TCCTCACGCA CGGCAACTCG GCCATGAACC CCATTGTCTA TGCCTTCCGC ATCCAGAAGT TCCGCGTCAC CTTCCTTAAG ATTTGGAATG ACCATTTCCG CTGCCAGCCT GCACCTCCCA TTGACGAGGA TCTCCCAGAA GAGAGGCCTG ATGACTAGAC CCCGCCTTCC GCTCCCACCG CCCACATCCA GTGGGGTCTC AGTCCAGTCC TCACATGCCC GCTGTCCCAG GGGTCTCCCT GAGCCTGCCC CAGCTGGGCT GTTGGCTGGG GGCATGGGGG AGGCTCTGAA GAGATACCCA CAGAGTGTGG TCCCTCCACT AGGAGTTAAC TACCCTACAC CTCTGGGCCC TGCAGGAGGC CTGGGAGGGC AAGGGTCCTA CGGAGGGACC AGGTGTCTAG AGGCAACAGT GTTCTGAGCC CCCACCTGCC TGACCATCCC

ATGAGCAGTC CAGAGCTTCA GGGCTGGGCA GGTCCTGGGG AGGCTGAGAC TGCAGAGGAG CCACCTGGGC TGGGAGAAGG TGCTTGGGCT TCTGCGGTGA GGCAGGGGAG TCTGCTTGTC TTAGATGTTG GTGGTGCAGC CCCAGGACCA AGCTTAAGGA GAGGAGAGCA TCTGCTCTGA GACGGATGGA AGGAGAGAGG TTGAGGATGC ACTGGCCTGT TCTGTAGGAG AGACTGGCCA GA CCCAGCCCCG AGGCTCAGAA GCGGCAGGCG GAGGCGCGGT CCGGGCGCTA TGGCCATGCC CGGCGGGTCT CACGCGGCTG CCCGTCGCCC GGCGCGCCTT CGGTAGGGGG CGCCCGGGGC CCAGCTGGCC CGGCCATGCT GCTGGAGACA CAGGACGCGC TGTACGTGGC GCTGGAGCTG GTCATCGCCG CGCTTTCGGT GGCGGGCAAC GTGCTGGTGT GCGCCGCGGT GGGCACGGCG AACACTCTGC AGACGCCCAC CAACTACTTC

CTGGTGTCCC TGGCTGCGGC CGACGTGGCC GTGGGGCTCT TCGCCATCCC CTTTGCCATC ACCATCAGCC TGGGCTTCTG CACTGACTTC TACGGCTGCC TCTTCCTCGC CTGCTTCGTG CTGGTGCTCA CGCAGAGCTC CATCTTCAGC CTTCTGGCCG TGGCAGTCGA CAGATACCTG GCCATCTGTG TCCCGCTCAG GTATAAAAGT TTGGTCACGG GGACCCGAGC AAGAGGGGTC ATTGCTGTCC TCTGGGTCCT TGCCTTTGGC ATCGGATTGA CTCCATTCCT GGGGTGGAAC AGTAAAGACA GTGCCACCAA CAACTGCACA GAACCCTGGG ATGGAACCAC GAATGAAAGC TGCTGCCTTG TGAAGTGTCT CTTTGAGAAT GTGGTCCCCA TGAGCTACAT GGTATATTTC AATTTCTTTG GGTGTGTTCT GCCCCCACTG CTTATAATGC TGGTGATCTA CATTAAGATC TTCCTGGTGG CCTGCAGGCA GCTTCAGCGC ACTGAGCTGA TGGACCACTC GAGGACCACC CTCCAGCGGG

AGATCCATGC AGCCAAGTCA CTGGCCATGA TTGTGGGGAT TTTTGCCCTG TGCTGGTTAC CTGTGCATGC TGTTAACTGT GTCACTCTTT TCCAGCCAGC TCAGGGTAAA AATAAGCCCA AGTGGGCAAT GAATATGGCC ATTCTTCTGT CACATGCCAA TTCAGTTGTC AATCCCATTG TCTATGCTTA CCGGAACCGA GACTTCCGCT ACACTTTTCA CAAAATTATC TCCAGGTATC TTCTCTGCCA AGCAGATGTC AAGAGTGGGA ATGGTCAGGC TGGGGTACAG CCTGCTCTCG GTGTGGGCCT ATGATCTAGG CTCTCGCCTC TTCCAGGAGA AGATACAAAT CCACAAGAAA CAAAGAGGAC ACGGCTGGTT TTCATTGTGA AAGATAGCTA CACCTCACAA GGAAATGGAC TGCCTCTCTT GAGCACTTCC CTGGAGCTAC CACGTATCTA GCTAATATGT ATGTGTCAGT AGTAGCACCA AGGATTGACA AATATATTTA TGATCTATTC AGCTGCTTTT ACTGTGTGGA TTATGCCAAC

AGCTTGAATG GATTCTAACA GACTCTTTTG TTTTTAAAAG TCTGCCTTGT TTATGGTGGA AAATTACTGA AACTATTTTA CTGTGAAACA GTGTGAACTA TTATAATGCA AATACTTTTT AACTTAGAGG CAATGGAAAA ATAAAAGTTG ACTGTACTAA AAATGTATAC TTGTTGCCAG GAAGGTGACC TCAAAAATTA AAAGTATAAT TATTCGGCCG GGCATGGTGG CTCACACCTG TAATTCCAGC ACTTTGGGAG GCCAAGGCAG GCGGATCACG AGGTCAGGAG TTCAAAACCA GCCTGTCCAA TATAGTG GGGCAATTTG TTAGTTATCC GCCGCCACCA AGACGCGGCA CGGCGCCTGG ACCGGAGGGG CCCCGCGCGG GCGCGAACTT TGGGCTCGGG CGAGTGGGTG GTGCTCCGCC CAGCCCGAGA CGGGCGGGCG CGCGGGCCAA TGGGTGCCGC CTCTTGGCCG CGGGGGGCCC CGACCCGTGG GTCCCGGCCA CCAGCGCCCC AGCCCCGAGG

CTCAGAAGCG GCAGGCGGAG GCGCGGTCCG GGCGCTATGG CCATGCCCGG CGGGTCTCAC GCGGCTGCCC CTCGCCCGGC GCGCCTTCGG TAGGGGGCGC CCGGGGCCCA GCTGGCCCGG CCATGCTGCT GGAGACACAG GACGCGCTGT ACGTGGCGCT GGAGCTGGTC ATCGCCGCGC TTTCGGTGGC GGGCAACGTG CTGGTGTGCG CCGCGGTGGG CACGGCGAAC ACTCTGCAGA CGCCCACCAA CTACTTCCTG GTGTCCCTGG CTGCGGCCGA CGTGGCCGTG GGGCTCTTCG CCATCCCCTT TGCCATCACC ATCAGCCTGG GCTTCTGCAC TGACTTCTAC GGCTGCCTCT TCCTCGCCTG CTTCGTGCTG GTGCTCACGC AGAGCTCCAT CTTCAGCCTT CTGGCCGTGG CAGTCGACAG ATACCTGGCC ATCTGTGTCC CGCTCAGGTA TAAAAGTTTG GTCACGGGGA CCCGAGCAAG AGGGGTCATT GCTGTCCTCT GGGTCCTTGC CTTTGGCATC GGATTGACTC

CATTCCTGGG GTGGAACAGT AAAGACAGTG CCACCAACAA CTGCACAGAA CCCTGGGATG GAACCACGAA TGAAAGCTGC TGCCTTGTGA AGTGTCTCTT TGAGAATGTG GTCCCCATGA GCTACATGGT ATATTTCAAT TTCTTTGGGT GTGTTCTGCC CCCACTGCTT ATAATGCTGG TGATCTACAT TAAGATCTTC CTGGTGGCCT GCAGGCAGCT TCAGCGCACT GAGCTGATGG ACCACTCGAG GACCACCCTC CAGCGGGAGA TCCATGCAGC CAAGTCACTG GCCATGATTG TGGGGATTTT TGCCCTGTGC TGGTTACCTG TGCATGCTGT TAACTGTGTC ACTCTTTTCC AGCCAGCTCA GGGTAAAAAT AAGCCCAAGT GGGCAATGAA TATGGCCATT CTTCTGTCAC ATGCCAATTC AGTTGTCAAT CCCATTGTCT ATGCTTACCG GAACCGAGAC TTCCGCTACA CTTTTCACAA AATTATCTCC AGGTATCTTC TCTGCCAAGC AGATGTCAAG AGTGGGAATG GTCAGGCTGG

GGTACAGCCT GCTCTCGGTG TGGGCCTATG ATCTAGGCTC TCGCCTCTTC CAGGAGAAGA TACAAATCCA CAAGAAACAA AGAGGACACG GCTGGTTTTC ATTGTGAAAG ATAGCTACAC CTCACAAGGA AATGGACTGC CTCTCTTGAG CACTTCCCTG GAGCTACCAC GTATCTAGCT AATATGTATG TGTCAGTAGT AGGCTCCAAG GATTGACAAA TATATTTATG ATCTATTCAG CTGCTTTTAC TGTGTGGATT ATGCCAACAG CTTGAATGGA TTCTAACAGA CTCTTTTGTT TTTAAAAGTC TGCCTTGTTT ATGGTGGAAA ATTACTGAAA CTATTTTACT GTGAAACAGT GTGAACTATT ATAATGCAAA TACTTTTTAA CTTAGAGGCA ATGGAAAAAT AAAAGTTGAC TGTACTAAAA ATG GAATTCCCAG ATGGGCAGAG GTGGCTGGGC TGGTGACCCT AAGTGTGTCT CCTGCCTTTA TTCTCTCTAG TGGGTTATTC TTTCATGTGG TATCTTGCCT ACAGCATGCT

GTGTTTGGAC ACAAACCCCT TTCCTTGGTT TCTCTGACCC AGCTGAGATG GACTGATTCC AAAAGAACTC ACCTATGTAC TGGGGTAGGG GAGGGAGGGT TTTTTGCAGT ATTTAACTAA GGTTCAAAGA GTGCTATATA GTGAGAAAGG CTTCTTTTTT χχ_TTTTTTTT TTTTTTGGCA GAGTGCTGCC TCCTAGAAAT TTCTCTTGGT AACTTCCTTC TCTGAAGCAC AGATAAAGAA AACAATTACA GTAGAAACAT TTATGAGGGA CACATTGGAG GCCGATGAAG CTTTTCAAGT TCCAGCAGTG CAGGGATGTG GGCAGAACTG ACATTGGAAA ATACTAGAAT GATGGAAATT CAGTTGGAGA GGACTGCCCT TTTTAATGTC TGGGGAGTCT GCTCAGGGAG AAATGACAAG TCTGGCGGGG ACAAGTATGG GATTTGGTAA GACTTGGATC AACTTGGGAT ACAGGGTGGG GGTCGGGAGT GGAATCAATG AATGATGCCA GAGCAGATCA ACTAACAAGA GGACCCTGAT

GAGCCCCAGG CAGAGGCGTC TCCCTTATGC CCCACTCTGA AGTGTTTGTT AGTAAACACC AGAACGCCAT TGTTGTTACT GCTGAATTTT ATTTTGGGCT GTACATATTT AGATGCTTAA GGTAAAAATG ATAAAGCCCT CAAGCCACTG TGTGGGTTTG GGTCCAAGTG TTCCTTCTTG CTGCCTCTCT AACACGCCTG GTTAAAATAA TCCCTTTGGA TGGTGCTGAG AAGCACCTGA ACCAAGTGGG TCCCCAAATA ACAATGGCGT GCAAGTGTCT GGTTCCCAGA AGTTGGTGAC TAGGTAAGCA GCTTCAGGGA GAGGGGGCTG ATTCCCAGAC AGTCGCCTGT TCCTGCGGGG ATGGGGCTGA GGCTTGGGGA ATGTGGGCAG GAGGATATGC CATTTGATTC TGTTGCACAC GTTCTTTTCC CTTCTTTCTG TATGTCTGGT CATTCTGCTA TTCTGTCGTT CCTCACATAG GTTGGACATT GGCCGGCTGC CAGCATAAGT GCCAGTGTGA TTTTGCTAGG TGTGAGCTGA

GAAAGAGAGG TGGAGGCTAA GCAGGTGTGA TGCTTCTCAG AGGTGCTGAG TTTTTGCCCT TCTGAGCAGG GAATCTTTGC TTATCCCTTT GACCAAGGAT CTTTGCTGCA AAGGCTGGGT ATCGGCTGTG CTCAGCAAAG CGTCAACTCG TGCAAGAACT TAGCAGGAAT AGTTCTGGCT AAGGTTAGGA GGCTGCCACC AAAGTCTCTT TTTTGTTCCT CTGCTTCTCC CGTTTGCCTC CTTATCATGA GATCTTTTTG CTAAGCTGGC AGAAAGATTG CATAGTCAGT GCTTCCAGCT CTGCTCCCAC CTGATCCTGC ACTGTCCTCT GGTCCCTGAA TGAATGAACT CTGATACCCA ATCTTGTCTC GAGCCTTCTC TATGCCACTC ATGGCTCCTC TTCTGCTCTT TCCATCTTTT TGCTGAGAGT TCTGAGCTCT GTACTTCCTC TTGGCCCATC TCACTTCCTG AAACACCCCT GAAGAGGGTT GCTTATCTTG ATGGAACTGA AAAAGCCAAA AAGCTGCAGG CAGAGGCGTT GAGGACATCT

GTTTGGGGAA CTAAGAGCAG CAGCACTTTC AGATTCAGTC CATATAGAGC TGTCCTACAG CATTCTGGAA ACTTGAGGAT GTGCGGTGCA TAAAGGGGCT GGAAGTGACC CACCTGTGAT GAGCCCTTTC TAAGGAGAAG GGTTTCCAAG AGATCACCCC ACCAGAAAAG GGTAGGAATG AGCAAGTTGG GAATTTTAGA CTGTCACTGC ACATGGACCT CTGGGAAGAC GTCTGGCGAG AGCTAGGCCC ACTGGCCCTA CAGACGGATC TTGCTGGCTC ACCTGTCCCT GTGGAGGTTC CCCTGGGAAG GCAAGATGCC CAACAACAGC ACTGCTCTGT CATTGGCCAA TGTTACCTAC ATCACCATGG AAATTTTCAT TGGACTCTGC GCCATAGTGG GCAACGTGCT GGTCATCTGC GTGGTCAAGC TGAACCCCAG CCTGCAGACC ACCACCTTCT ATTTCATTGT CTCTCTAGCC CTGGCTGACA TTGCTGTTGG GGTGCTGGTC ATGCCTTTGG CCATTGTTGT CAGCCTGGGC ATCACAATCC

ACTTCTACAG CTGCCTTTTT ATGACTTGCC TACTGCTTAT CTTTACCCAC GCCTCCATCA TGTCCTTGCT GGCCATCGCT GTGGACCGAT ACTTGCGGGT CAAGCTTACC GTCAGGTAGC CTGCGGCGTG GGGTGGGCAG CAATTGAGGC AGCTGGGAAA TGAGGCTACA AAGCCAGAGC CTGCTGAATT TTATTTTGGA CTGTACATAT

TTAGATGCTT AAGGTAAAAA TGATAAAGCC CTCAAGCCAC TGTGTGGGTT GGGTCCAAGT GTTCCTTGCT GCTGCCTCTC TAACACGCCT GGTTAAAATA ATCCCTTTGG ATGGTGCTGA GAAGCACCTG AACCAAGTGG GTCCCCAAAT AACTATGGCG TGCAAGTGTC TGGTTCCCAG AAGTTGGTGA CTAGGTAAGC GACTCAGGGA GAGGGGCTGA TTCCCAGACA GTCGCCTGTT CCTGCTGGGA TGGGGCTGAG GCTTGGGGAA TGTGGGCAGG AGGATATGCC ATTTGATTCT GTTGCACACG TTCTTTTCCC TTCTTTCTGT ATGTCTGGTC ATTCTGCTAT TCTGTCGTTC CTCACATAGG TTGGACATTG GCCGGCTGCC AGCATAAGTG CCAGTGTGAT TTTGCTAGGG TGTGAGCTGA GAAAGAGAGG TGGAGGCTAA GCAGGTGTGA TGCTTCTCAG AGGTGCTGAG TTTTTGCCCT TCTGAGCAGG GAATCTTTGC TTATCCCTTT GACCAAGGAT CTTTGCTCCA AAGGCTGGGT ATCGGCTGTG CTCAGCAAAG CGTCAACTCG TGCAAGAACT TAGCAGGAAT AGTTCTGGCT AAGGTTAGGA GGCTGCCACC AAAGTCTCTT TTTTGTTCCT CTGCTTCTCC CGTTTGCCTC CTTATCATGA GATCTTTTTG CTAAGCTGGC AGAAAGATTG CATAATCAGT GCTTCCAGCT CCGCTCCCAC CTGATCCTGC ACTGTCCTCT

GGTCCCTGAA TGAATGAACT CTGATACCCA ATCTTGTCTC GAGCCTTCTC TATGCCACTC ATGGCTCCTC TTCTGCTCTT TCCATCTTTT TGCTGAGAGT TACTGAGCTC TGTACTTCCT CTTGGCCCAT CTCACTTCCT GAAACACCCC TGAAGAGGGT TGCTTATCTT GATGGAACTC AAAAAGCCAA AAAGCTGCAG GCAGAGGCGT TGAGGACATC TGTTTGGGGA ACTAAGAGCA GCAGCACTTT CAGATTCAGT CCATATAGAG CTGTCCTACA GCATTCTGGA AACTTGAGGA TGTGCGGTGC ATAAAGGGGC TGGAAGTGAC CCACCTGTGA TGAGCCCTTT CTAAGGAGAA GGGTTTCCAA GAGATCACCC CACCAGAAAA GGGTAGGAAT GAGCAAGTTG GGAATTTTAG ACTGTCACTG CACATGGACC TCTGGGAAGA CGTCTGGCGA GAGCTAGGCC CACTGGCCCT ACAGACGGAT CTTGCTGGCT CACCTGTCCC TGTGGAGGTT CCCCTGGGAA GGCAAGATGC CCAACAACAG

CACTGCTCTG CGAATTCGGG GGACATCTGT TTGGGGAACT AAGAGCAGCA GCACTTTCAG ATTCAGTCCA TATAGAGCTG TCCTACAGCA TTCTGGAAAC TTGAGGATGT GCGGTGCATA AACGGGCTGG AAGTGACCCA CCTGTGATGA GCCCTTTCTA AGGAGAAGGG TTTCCAAGAG ATCACCCCAC CAGAAAAGGG TAGGAATGAG CAAGTTGGGA ATTTTAGACT GTCACTGCAC ATGGACCTCT GGGAAGACGT CTGGCGAGAG CTAGGCCCAC TGGCCCTACA GACGGATCTT GCTGGCTCAC CTGTCCCTGT GGAGGTTCCC CTGGGAAGGC AAGATGCCCA ACAACAGCAC TGCTCTGTCA TTGGCCAATG TTACCTACAT CACCATGGAA ATTTTCATTG GACTCTGCGC CATAGTGGGC AACGTGCTGG TCATCTGCGT GGTCAAGCTG AACCCCAGCC TGCAGACCAC CACCTTCTAT TTCATTGTCT CTCTAGCCCT GGCTGACATT GCTGTTGGGG TGCTGGTCAT

GCCTTTGGCC ATTGTTGTCA GCCTGGGCAT CACAATCCAC TTCTACAGCT GCCTTTTTAT GACTTGCCTA CTGCTTATCT TTACCCACGC CTCCATCATG TCCTTGCTGG CCATCGCTGT GGACCGATAC TTGCGGGTCA AGCTTACCGT CAGATACAAG AGGGTCACCA CTCACAGAAG AATATGGCTG GCCCTGGGCC TTTGCTGGCT GGTGTCATTC CTGGTGGGAT TGACCCCCAT GTTTGGCTGG AACATGAAAC TGACCTCAGA GTACCACAGA AATGTCACCT TCCTTTCATG CCAATTTGTT TCCGTCATGA GGATGGACTA CATGGTATAC TTCAGCTTCC TCACCTGGAT TTTCATCCCC CTGGTTGTCA TGTGCGCCAT CTATCTTGAC ATCTTTTACA TCATTCGGAA CAAACTCAGT CTGAACTTAT CTAACTCCAA AGAGACAGGT GCATTTTATG GACGGGAGTT CAAGACGGCT AAGTCCTTGT TTCTGGTTCT TTTCTTGTTT GCTCTGTCAT GGCTGCCTTT ATCTCTCATC

AACTGCATCA TCTACTTTAA TGGTGAGGTA CCACAGCTTG TGCTGTACAT GGGCATCCTG CTGTCCCATG CCAACTCCAT GATGAACCCT ATCGTCTATG CCTATAAAAT AAAGAAGTTC AAGGAAACCT ACCTTTTGAT CCTCAAAGCC TGTGTGGTCT GCCATCCCTC TGATTCTTTG GACACAAGCA TTGAGAAGAA TTCTGAGTAG TTATCCATCA GAGATGACTC TGTCTCATTG ACCTTCAGAT TCCCCATCAA CAAACACTTG AGGGCCTGTA TGCCTGGGCC AAGGGATTTT TACATCCTTG ATTACTTCCA CTGAGGTGGG AGCATCTCCA GTGCTCCCCA ATTATATCTC CCCCACTCCA CTACTCTCTT CCTCCACTTC ATTTTTCCTT TGTCCTTTCT CTCTAATTCA GTGTTTTGGA GGCCTGACTT GGGGACAACG TATTATTGAT ATTATTGTCT GTTTTCCTTC TTCCCAATAG AAGAATAAGT CATGGAGCCT GAAGGGTGCC TAGTTGACTT ACTGACAAAA GGCTCTAGTT

GGGCTGAACA TGTGTGTGGT GGTGACTCAT TTCCATGCCA TTGTGGAATT GAGCAGAGAA CCTGCTCTCG GAGGATGCCT AGGAGATGTT GGGAACAGAA GAAATAAACT GAGTTTAAGG GGGACTTAAA CTGCTGAATT C CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG TCTCCGGTAA AACACCGGAG ACTAATTCCT GCCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC AGGAGTGGAG GAGGCCTGGG GGGAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC TCCGTCCCTG CCCCAGCAAG

ACAACTTAGA TCTCCAGGAG AACTGCCATC CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT CTTTAATCTA TTCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGAGGTC TGTGCCAAAG AAGAATCCAA TAAGCACATA TTGAGCACTT GCTGTATATG CAGTATTGAG CACTGTAGGC AAGACCCAAG AAAGAGAAGG AGCCATCTCC ATCTTGAAGG AACTCAAAGA CTCAAGTGGG AACGACTGGG CACTGCCACC ACCAGAAAGC TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC ACAACCACCT GTCCCTGCCT CAGTTCCCTT TTATGTAACA TGAAGTCGTT GTGAGGGTTA AAGGCAGTAA CAGGTATAAA

GTACTTAGAA AAGCAAAGGG TGCTACGTAC ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT ACTATAAGGA AAAGACACTG AGGTCTAGAA ATAGCTCCGT GGAGCAGAAT CAGTATTGGG AGCCGGTGGC GGTGTGAAGC ACCAGTGTCT GGCACACAGT AGGTGCTCAT TGGCTCCCTT CCACCTGTCA TTCCCACCAC CCTGAGGCCC CAACCGCCAC ACACACAGGA GCATTTGGAG AGAAGGCCAT GTCTTCAAAG TCTGATTTGT GATGAGGCAG AGGAAGATAT TTCTAATCGG TCTTGCCCAG AGGATCACAG TGCTGAGACC CCCCACCACC AGCCGGTACC TGGGAAGGGG GAGAGTGCAG GCCTGCTCAG GGACTGTTCC TGTCTCAGCA ACCAAGGGAT TGTTCCTGTC AATCAATGGT TTATTGGAAG GTGGCCCAGT ATGAGCCCTA GAAGAGTGTG AAAAGGAATG GCAATGGTGT TCACCATCGG CAGTGCCAGG GCAGCACTCA TTCACTTGAT AAATGAATAT

TTATTAGCTG GTTGGAGAGC TAGAACCTGG AGAGCTAGAA CCTGGAGAAC TAGAACCTGG AGGGCTAGAA CCTGGAGAGG CTAGAACCAA GAAGGGCTAG AACCTGGAGG GGCTAGAACC TAGAGAAGCT AAAACCTGAG CTAGAAGCTG GAGGACTAGA ACCTGGAGGG CTGGAATCTG AAGGGCTAGA ACCTGGAGGG CTGGAATCTG GAGAGCTAGA ACCTGGAGGG CTAGAACCTG GAGGGCTAGA ACCTAGAAGG GCTAGAACCT GGAGGGCTGG AATCTGGAGA GCTAGAACCT GGAGGGCTAG AACCTGGAGG GCTAGAACCT AGAAGGGCTA GAACCTGGAG GGCTAGAACC TGGCAGGTTA GAACCTAGAA GGGCTAGAAC CTGGAGAGCC AGAACCTGGA GGGCTAGAAC CTGGAAGGGC TAGAACCTGT AGAGCTAGAA CATGGAGAGC TAGAACCCGG CAGGCTAGAA CCTGGCAAGC TAGAACCTGG

AGGGAATGAA CCTGGAGGGC TAGAACCTGG AGAATGAGAA AAATTTACAT GGCAAAGAGC CCATAAATCC TGACCAATCC AACTCTGAAT TTTAAAGCAA AAGCGTGAAA AAAAAGATTC CCTCCTTACC CCCAACCCAC TCTTTTTTCC CACCACCCAC TCTCCTCTGC CTCAGTAAGT ATCTGGAGGA AGAAAACAGG TGAAAGAAGA AGTAAAAACC ATTTAGTATT AGTATTAGAA TGAAGTCAAA CTGTGCCACA CATGGTGAAT GAAAAAAAAA AAAAAGAGGC TGTGTTTTGT CACACAGGGC AGTCATTCAG CACCAGAGCA CGTGATGGTC TGAGACTCTC TTAGGAGCAG AGCTCTGCCG CAATGGCCAT GTGGGGATCC ACACCTGGTC TGAGGGGCAA CTGAGTCTGC GGGAGAAGAG CGGCCCTATG CATGGTGTAG ATGCCCTGAT AAAGAACATC TGTCCTGTGA AAGACTCAAT GAGCTGTTAT GTTGTAAACA GGAAGCATTT CACATCCAAA

CGAGAAAATC ATGTAAACAT GTGTCTTTTC TGTAGAGCAT AATAAATGGA TGAGGTTTTT GCAAAAAAAA AAAAAAAAA ATGCCGCCCT CCATCTCAGC TTTCCAGGCC GCCTACATCG GCATCGAGGT GCTCATCGCC CTGGTCTCTG TGCCCGGGAA CGTGCTGGTG ATCTGGGCGG TGAAGGTGAA CCAGGCGCTG CGGGATGCCA CCTTCTGCTT CATCGTCTCG CTGGCGGTGG CTGATGTGGC CGTGGGTGCC CTGGTCATCC CCCTCGCCAT CCTCATCAAC ATTGGGCCAC AGACCTACTT CCACACCTGC CTCATGGTTG CCTGTCCGGT CCTCATCCTC ACCCAGAGCT CCATCCTGGC CCTGCTGGCA ATTGCTGTGG ACCGCTACCT CCGGGTCAAG ATCCCTCTCC GGTACAAGAT GGTGGTGACC CCCCGGAGGG CGGCGGTGGC CATAGCCGGC TGCTGGATCC TCTCCTTCGT GGTGGGACTG ACCCCTATGT TTGGCTGGAA CAATCTGAGT GCGGTGGAGC GGGCCTGGGC

AGCCAACGGC AGCATGGGGG AGCCCGTGAT CAAGTGCGAG TTCGAGAAGG TCATCAGCAT GGAGTACATG GTCTACTTCA ACTTCTTTGT GTGGGTGCTG CCCCCGCTTC TCCTCATGGT CCTCATCTAC CTGGAGGTCT TCTACCTAAT CCGCAAGCAG CTCAACAAGA AGGTGTCGGC CTCCTCCGGC GACCCGCAGA AGTACTATGG GAAGGAGCTG AAGATCGCCA AGTCGCTGGC CCTCATCCTC TTCCTCTTTG CCCTCAGCTG GCTGCCTTTG CACATCCTCA ACTGCATCAC CCTCTTCTGC CCGTCCTGCC ACAAGCCCAG CATCCTTACC TACATTGCCA TCTTCCTCAC GCACGGCAAC TCGGCCATGA ACCCCATTGT CTATGCCTTC CGCATCCAGA AGTTCCGCGT CACCTTCCTT AAGATTTGGA ATGACCATTT CCGCTGCCAG CCTGCACCTC CCATTGACGA GGATCTCCCA GAAGAGAGGC CTGATGACTA G ATGAGTGTCA GAAGTGTGAA GGGTGCCTGT

TCTGAATCCC AGAGCCTCCT CTCCCTCTGT GAGGCTGGCA GGTGAGGAAG GGTTTAACCT CACTGGAAGG AATCCCTGGA GCTAGCGGCT GCTGAAGGCG TCGAGGTGTG GGGGCACTTG GACAGAACAG TCAGGCAGCC GGGAGCTCTG CCAGCTTTGG TGACCTTGGG CCGGGCTGGG AGCGCTGCGG CGGGAGCCGG AGGACTATGA GCTGCCGCGC GTTGTCCAGA GCCCAGCCCA GCCCTACGCG CGCGGCCCGG AGCTCTGTTC CCTGGAACTT TGGGCACTGC CTCTGGGACC CCTGCCGGCC AGCAGGCAGG ATGGTGCTTG CCTCGTGCCC CTTGGTGCCC GTCTGCTGAT GTGCCCAGCC TGTGCCCGCC ATGCCGCCCT CCATCTCAGC TTTCCAGGCC GCCTACATCG GCATCGAGGT GCTCATCGCC CTGGTCTCTG TGCCCGGGAA CGTGCTGGTG ATCTGGGCGG TGAAGGTGAA CCAGGCGCTG CGGGATGCCA CCTTCTGCTT CATCGTGTCG CTGGCGGTGG

CTGATGTGGC CGTGGGTGCC CTGGTCATCC CCCTCGCCAT CCTCATCAAC ATTGGGCCAC AGACCTACTT CCACACCTGC CTCATGGTTG CCTGTCCGGT CCTCATCCTC ACCCAGAGCT CCATCCTGGC CCTGCTGGCA ATTGCTGTGG ACCGCTACCT CCGGGTCAAG ATCCCTCTCC GGTACAAGAT GGTGGTGACC CCCCGGAGGG CGGCGGTGGC CATAGCCGGC TGCTGGATCC TCTCCTTCGT GGTGGGACTG ACCCCTATGT TTGGCTGGAA CAATCTGAGT GCGGTGGAGC GGGCCTGGGC AGCCAACGGC AGCATGGGGG AGCCCGTGAT CAAGTGCGAG TTCGAGAAGG TCATCAGCAT GGAGTACATG GTCTACTTCA ACTTCTTTGT GTGGGTGCTG CCCCCGCTTC TCCTCATGGT CCTCATCTAC CTGGAGGTCT TCTACCTAAT CCGCAAGCAG CTCAACAAGA AGGTGTCGGC CTCCTCCGGC GACCCGCAGA AGTACTATGG GAAGGAGCTG AAGATCGCCA AGTCGCTGGC

CCTCATCCTC TTCCTCTTTG CCCTCAGCTG GCTGCCTTTG CACATCCTCA ACTGCATCAC CCTCTTCTGC CCGTCCTGCC ACAAGCCCAG CATCCTTACC TACATTGCCA TCTTCCTCAC GCACGGCAAC TCGGCCATGA ACCCCATTGT CTATGCCTTC CGCATCCAGA AGTTCCGCGT CACCTTCCTT AAGATTTGGA ATGACCATTT CCGCTGCCAG CCTGCACCTC CCATTGACGA GGATCTCCCA GAAGAGAGGC CTGATGACTA GACCCCGCCT TCCGCTCCCA CCAGCCCACA TCCAGTGGGG TCTCAGTCCA GTCCTCACAT GCCCGCTGTC CCAGGGGTCT CCCTGAGCCT GCCCCAGCTG GGCTGTTGGC TGGGGGCATG GGGGAGGCTC TGAAGAGATA CCCACAGAGT GTGGTCCCTC CACTAGGAGT TAACTACCCT ACACCTCTGG GCCCTGCAGG AGGCCTGGGA GGGCAAGGGT CCTACGGAGG GACCAGGTGT CTAGAGGCAA CAGTGTTCTG AGCCCCCACC TGCCTGACCA

TCCCATGAGC AGTCCAGCGC TTCAGGGCTG GGCAGGTCCT GGGGAGGCTG AGACTGCAGA GGAGCCACCT GGGCTGGGAG AAGGTGCTTG GGCTTCTGCG GTGAGGCAGG GGAGTCTGCT TGTCTTAGAT GTTGGTGGTG CAGCCCCAGG ACCAAGCTTA AGGAGAGGAG AGCATCTGCT CTGAGACGGA TGGAAGGAGA GAGGTTGAGG ATGCACTGGC CTGTTCTGTA GGAGAGACTG GCCAGAGGCA GCTAAGGGGC AGGAATCAAG GAGCCTCCGT TCCCACCTCT GAGGACTCTG GACCCCAGGC CATACCAGGT GCTAGGGTGC CTGCTCTCCT TGCCCTGGGC CAGCCCAGGA TTGTACGTGG GAGAGGCAGA AAGGGTAGGT TCAGTAATCA TTTCTGATGA TTTGCTGGAG TGCTGGCTCC ACGCCCTGGG GAGTGAGCTT GGTGCGGTAG GTGCTGGCCT CAAACAGCCA CGAGGTGGTA GCTCTGAGCC CTCCTTCTTG CCCTGAGCTT

TCCGGGGAGG AGCCTGGAGT GTAATTACCT GTCATCTGGG CCACCAGCTC CACTGGCCCC CGTTGCCGGG CCTGGACTGT CCTAGGTGAC CCCATCTCTG CTGCTTCTGG GCCTGATGGA GAGGAGAACA CTAGACATGC CAACTCGGGA GCATTCTGCC TGCCTGGGAA CGGGGTGGAC GAGGGAGTGT CTGTAAGGAC TCAGTGTTGA CTGT AGGCGC CCCTGGGGTG GGTTTAGCAG GCTGCAGCAG GCAGAGGAGG AGT ACCCCCC TGAGAGCATG TGGGGGAAGG CCTTGCTGTC ATGTGAATCC CTCAATACCC CTAGTATCTG GCTGGGTTTT CAGGGGCTTT GGAAGCTCTG TTGCAGGTGT CCGGGGGTCT AGGACTTTAG GGATCTGGGA TCTGGGGAAG GACCAACCCA TGCCCTGCCA AGCCTGGAGC CCCTGTGTTG GGGGGCAAGG TGGGGGAGCC TGGAGCCCCT GTGTGGGAGG GCGAGGCGGG GGAGCCTGGA GCCCCTGTGT GGGAGGGCGA

GGCGGGGGAT CCTGGAGCCC CTGTGTCGGG GGGCGAGGGA GGGGAGGTGG CCGTCGGTTG ACCTTCTGAA CATGAGTGTC AACTCCAGGA CTTGCTTCCA AGCCCTTCCC TCTGTTGGAA ATTGGGTGTG CCCTGGCTCC CAAGGGAGGC CCATGTGACT AATAAAAAAC TGTGAACCCT CGCATTTGTG TTTTAATAAA AGAATCTGGA AGATAAATAG TCTTGAAGAG AGACAAAGGA AGGAAAATTT AAATCCTTAG ATTCAAGCAG AAGAATTCCA TGTGGAAGGT TTGGGTTGTT GTTGTTGTTG TTTGGTGTGT TTTTTGTTTT TTTGTTTTTT TGTTTTTTTT TGAGATGGAG TCTCGCTGTG TTACCGGGAG CGACAGAGCC GCACGGCCGA GTCGAGTCCC AGCCAGCTAC CATCCCTCTG GAGCTTACCG GCCGGCCTTG GCTTCCCCAG GAATCCCTGG AGCTAGCGGC TGCTGAAGGC GTCGAGGTGT GGGGGCACTT GGACAGAACA GTCAGGCAGC CGGGAGCTCT GCCAGCTTTG

GTGACCTTGG GTGCTTGCCT CGTGCCCCTT GGTGCCCGTC TGCTGATGTG CCCAGCCTGT GCCCGCCATG CCGCCCTCCA TCTCAGCTTT CCAGGCCGCC TACATCGGCA TCGAGGTGCT CATCGCCCTG GTCTCTGTGC CCGGGAACGT GCTGGTGATC TGGGCGGTGA AGGTGAACCA GGCGCTGCGG GATGCCACCT TCTGCTTCAT CGTGTCGCTG GCGGTGGCTG ATGTGGCCGT GGGTGCCCTG GTCATCCCCC TCGCCATCCT CATCAACATT GGGCCACAGA CCTACTTCCA CACCTGCCTC ATGGTTGCCT GTCCGGTCCT CATCCTCACC CAGAGCTCCA TCCTGGCCCT GCTGGCAATT GCTGTGGACC GCTACCTCCG GGTCAAGATC CCTGTCCGGT ACAAGATGGT GGTGACCCCC CGGAGGGCGG CGGTGGCCAT AGCCGGCTGC TGGATCCTCT CCTTCGTGGT GGGACTGACC CCTATGTTTG GCTGGAACAA TCTGAGTGCG GTGGAGCGGG CCTGGGCAGG CAACGGCAGC

ATGGGGGAGC CCGTGATCAA GTGCGAGTTC GAGAAGGTCA TCAGCATGGA GTACATGGTC TACTTCAACT TCTTTGTGTG GGTGCTGCCC CCGCTTCTCC TCATGGTCCT CATCTACCTG GAGGTCTTCT ACCTAATCCG CAAGCAGCTC AACAAGAAGG TGTCGGCCTC CTCCGGCGAC CCGCAGAAGT ACTATGGGAA GGAGCTGAAG ATCGCCAAGT CGCTGGCCCT CATCCTCTTC CTCTTTGCCC TCAGCTGGCT GCCTTTGCAC ATCCTCAACT GCATCACCCT CTTCTGCCCG TCCTGCCACA AGCCCAGCAT CCTTACCTAC ATTGCCATCT TCCTCACGCA CGGCAACTCG GCCATGAACC CCATTGTCTA TGCCTTCCGC ATCCAGAAGT TCCGCGTCAC CTTCCTTAAG ATTTGGAATG ACCATTTCCG CTGCCAGCCT GCACCTCCCA TTGACGAGGA TCTCCCAGAA GAGAGGCCTG ATGACTAGAC CCCGCCTTCC GCTCCCACCG CCCACATCCA GTGGGGTCTC AGTCCAGTCC TCACATGCCC GCTGTCCCAG GGGTCTCCCT GAGCCTGCCC CAGCTGGGCT GTTGGCTGGG GGCATGGGGG AGGCTCTGAA GAGATACCCA CAGAGTGTGG TCCCTCCACT AGGAGTTAAC TACCCTACAC CTCTGGGCCC TGCAGGAGGC CTGGGAGGGC AAGGGTCCTA CGGAGGGACC AGGTGTCTAG AGGCAACAGT GTTCTGAGCC CCCACCTGCC TGACCATCCC ATGAGCAGTC CAGAGCTTCA GGGCTGGGCA GGTCCTGGGG AGGCTGAGAC TGCAGAGGAG CCACCTGGGC TGGGAGAAGG TGCTTGGGCT TCTGCGGTGA GGCAGGGGAG TCTGCTTGTC TTAGATGTTG GTGGTGCAGC CCCAGGACCA AGCTTAAGGA GAGGAGAGCA TCTGCTCTGA GACGGATGGA

AGGAGAGAGG TTGAGGATGC ACTGGCCTGT TCTGTAGGAG AGACTGGCCA GA CCCAGCCCCG AGGCTCAGAA GCGGCAGGCG GAGGCGCGGT CCGGGCGCTA TGGCCATGCC CGGCGGGTCT CACGCGGCTG CCCGTCGCCC GGCGCGCCTT CGGTAGGGGG CGCCCGGGGC CCAGCTGGCC CGGCCATGCT GCTGGAGACA CAGGACGCGC TGTACGTGGC GCTGGAGCTG GTCATCGCCG CGCTTTCGGT GGCGGGCAAC GTGCTGGTGT GCGCCGCGGT GGGCACGGCG AACACTCTGC AGACGCCCAC CAACTACTTC CTGGTGTCCC TGGCTGCGGC CGACGTGGCC GTGGGGCTCT TCGCCATCCC CTTTGCCATC ACCATCAGCC TGGGCTTCTG CACTGACTTC TACGGCTGCC TCTTCCTCGC CTGCTTCGTG CTGGTGCTCA CGCAGAGCTC CATCTTCAGC CTTCTGGCCG TGGCAGTCGA CAGATACCTG GCCATCTGTG TCCCGCTCAG GTATAAAAGT

TTGGTCACGG GGACCCGAGC AAGAGGGGTC ATTGCTGTCC TCTGGGTCCT TGCCTTTGGC ATCGGATTGA CTCCATTCCT GGGGTGGAAC AGTAAAGACA GTGCCACCAA CAACTGCACA GAACCCTGGG ATGGAACCAC GAATGAAAGC TGCTGCCTTG TGAAGTGTCT CTTTGAGAAT GTGGTCCCCA TGAGCTACAT GGTATATTTC AATTTCTTTG GGTGTGTTCT GCCCCCACTG CTTATAATGC TGGTGATCTA CATTAAGATC TTCCTGGTGG CCTGCAGGCA GCTTCAGCGC ACTGAGCTGA TGGACCACTC GAGGACCACC CTCCAGCGGG AGATCCATGC AGCCAAGTCA CTGGCCATGA TTGTGGGGAT TTTTGCCCTG TGCTGGTTAC CTGTGCATGC TGTTAACTGT GTCACTCTTT TCCAGCCAGC TCAGGGTAAA AATAAGCCCA AGTGGGCAAT GAATATGGCC ATTCTTCTGT CACATGCCAA TTCAGTTGTC AATCCCATTG TCTATGCTTA CCGGAACCGA GACTTCCGCT

ACACTTTTCA CAAAATTATC TCCAGGTATC TTCTCTGCCA AGCAGATGTC AAGAGTGGGA ATGGTCAGGC TGGGGTACAG CCTGCTCTCG GTGTGGGCCT ATGATCTAGG CTCTCGCCTC TTCCAGGAGA AGATACAAAT CCACAAGAAA CAAAGAGGAC ACGGCTGGTT TTCATTGTGA AAGATAGCTA CACCTCACAA GGAAATGGAC TGCCTCTCTT GAGCACTTCC CTGGAGCTAC CACGTATCTA GCTAATATGT ATGTGTCAGT AGTAGCACCA AGGATTGACA AATATATTTA TGATCTATTC AGCTGCTTTT ACTGTGTGGA TTATGCCAAC AGCTTGAATG GATTCTAACA GACTCTTTTG TTTTTAAAAG TCTGCCTTGT TTATGGTGGA AAATTACTGA AACTATTTTA CTGTGAAACA GTGTGAACTA TTATAATGCA AATACTTTTT AACTTAGAGG CAATGGAAAA ATAAAAGTTG ACTGTACTAA AAATGTATAC TTGTTGCCAG GAAGGTGACC TCAAAAATTA AAAGTATAAT

TATTCGGCCG GGCATGGTGG CTCACACCTG TAATTCCAGC ACTTTGGGAG GCCAAGGCAG GCGGATCACG AGGTCAGGAG TTCAAAACCA GCCTGTCCAA TATAGTG GGGCAATTTG TTAGTTATCC GCCGCCACCA AGACGCGGCA CGGCGCCTGG ACCGGAGGGG CCCCGCGCGG GCGCGAACTT TGGGCTCGGG CGAGTGGGTG GTGCTCCGCC CAGCCCGAGA CGGGCGGGCG CGCGGGCCAA TGGGTGCCGC CTCTTGGCCG CGGGGGGCCC CGACCCGTGG GTCCCGGCCA CCAGCGCCCC AGCCCCGAGG CTCAGAAGCG GCAGGCGGAG GCGCGGTCCG GGCGCTATGG CCATGCCCGG CGGGTCTCAC GCGGCTGCCC CTCGCCCGGC GCGCCTTCGG TAGGGGGCGC CCGGGGCCCA GCTGGCCCGG CCATGCTGCT GGAGACACAG GACGCGCTGT ACGTGGCGCT GGAGCTGGTC ATCGCCGCGC TTTCGGTGGC

GGGCAACGTG CTGGTGTGCG CCGCGGTGGG CACGGCGAAC ACTCTGCAGA CGCCCACCAA CTACTTCCTG GTGTCCCTGG CTGCGGCCGA CGTGGCCGTG GGGCTCTTCG CCATCCCCTT TGCCATCACC ATCAGCCTGG GCTTCTGCAC TGACTTCTAC GGCTGCCTCT TCCTCGCCTG CTTCGTGCTG GTGCTCACGC AGAGCTCCAT CTTCAGCCTT CTGGCCGTGG CAGTCGACAG ATACCTGGCC ATCTGTGTCC CGCTCAGGTA TAAAAGTTTG GTCACGGGGA CCCGAGCAAG AGGGGTCATT GCTGTCCTCT GGGTCCTTGC CTTTGGCATC GGATTGACTC CATTCCTGGG GTGGAACAGT AAAGACAGTG CCACCAACAA CTGCACAGAA CCCTGGGATG GAACCACGAA TGAAAGCTGC TGCCTTGTGA AGTGTCTCTT TGAGAATGTG GTCCCCATGA GCTACATGGT ATATTTCAAT TTCTTTGGGT GTGTTCTGCC CCCACTGCTT ATAATGCTGG TGATCTACAT TAAGATCTTC

CTGGTGGCCT GCAGGCAGCT TCAGCGCACT GAGCTGATGG ACCACTCGAG GACCACCCTC CAGCGGGAGA TCCATGCAGC CAAGTCACTG GCCATGATTG TGGGGATTTT TGCCCTGTGC TGGTTACCTG TGCATGCTGT TAACTGTGTC ACTCTTTTCC AGCCAGCTCA GGGTAAAAAT AAGCCCAAGT GGGCAATGAA TATGGCCATT CTTCTGTCAC ATGCCAATTC AGTTGTCAAT CCCATTGTCT ATGCTTACCG GAACCGAGAC TTCCGCTACA CTTTTCACAA AATTATCTCC AGGTATCTTC TCTGCCAAGC AGATGTCAAG AGTGGGAATG GTCAGGCTGG GGTACAGCCT GCTCTCGGTG TGGGCCTATG ATCTAGGCTC TCGCCTCTTC CAGGAGAAGA TACAAATCCA CAAGAAACAA AGAGGACACG GCTGGTTTTC ATTGTGAAAG ATAGCTACAC CTCACAAGGA AATGGACTGC CTCTCTTGAG CACTTCCCTG GAGCTACCAC GTATCTAGCT AATATGTATG TGTCAGTAGT

AGGCTCCAAG GATTGACAAA TATATTTATG ATCTATTCAG CTGCTTTTAC TGTGTGGATT ATGCCAACAG CTTGAATGGA TTCTAACAGA CTCTTTTGTT TTTAAAAGTC TGCCTTGTTT ATGGTGGAAA ATTACTGAAA CTATTTTACT GTGAAACAGT GTGAACTATT ATAATGCAAA TACTTTTTAA CTTAGAGGCA ATGGAAAAAT AAAAGTTGAC TGTACTAAAA ATG GAATTCCCAG ATGGGCAGAG GTGGCTGGGC TGGTGACCCT AAGTGTGTCT CCTGCCTTTA TTCTCTCTAG TGGGTTATTC TTTCATGTGG TATCTTGCCT ACAGCATGCT GTGTTTGGAC ACAAACCCCT TTCCTTGGTT TCTCTGACCC AGCTGAGATG GACTGATTCC AAAAGAACTC ACCTATGTAC TGGGGTAGGG GAGGGAGGGT TTTTTGCAGT ATTTAACTAA GGTTCAAAGA GTGCTATATA GTGAGAAAGG CTTCTTTTTT _{ττττττττττ} TTTTTTGGCA GAGTGCTGCC TCCTAGAAAT

TTCTCTTGGT AACTTCCTTC TCTGAAGCAC AGATAAAGAA AACAATTACA GTAGAAACAT TTATGAGGGA CACATTGGAG GCCGATGAAG CTTTTCAAGT TCCAGCAGTG CAGGGATGTG GGCAGAACTG ACATTGGAAA ATACTAGAAT GATGGAAATT CAGTTGGAGA GGACTGCCCT TTTTAATGTC TGGGGAGTCT GCTCAGGGAG AAATGACAAG TCTGGCGGGG ACAAGTATGG GATTTGGTAA GACTTGGATC AACTTGGGAT ACAGGGTGGG GGTCGGGAGT GGAATCAATG AATGATGCCA GAGCAGATCA ACTAACAAGA GGACCCTGAT GAGCCCCAGG CAGAGGCGTC TCCCTTATGC CCCACTCTGA AGTGTTTGTT AGTAAACACC AGAACGCCAT TGTTGTTACT GCTGAATTTT ATTTTGGGCT GTACATATTT AGATGCTTAA GGTAAAAATG ATAAAGCCCT CAAGCCACTG TGTGGGTTTG GGTCCAAGTG TTCCTTCTTG CTGCCTCTCT AACACGCCTG

GTTAAAATAA TCCCTTTGGA TGGTGCTGAG AAGCACCTGA ACCAAGTGGG TCCCCAAATA ACAATGGCGT GCAAGTGTCT GGTTCCCAGA AGTTGGTGAC TAGGTAAGCA GCTTCAGGGA GAGGGGGCTG ATTCCCAGAC AGTCGCCTGT TCCTGCGGGG ATGGGGCTGA GGCTTGGGGA ATGTGGGCAG GAGGATATGC CATTTGATTC TGTTGCACAC GTTCTTTTCC CTTCTTTCTG TATGTCTGGT CATTCTGCTA TTCTGTCGTT CCTCACATAG GTTGGACATT GGCCGGCTGC CAGCATAAGT GCCAGTGTGA TTTTGCTAGG TGTGAGCTGA GAAAGAGAGG TGGAGGCTAA GCAGGTGTGA TGCTTCTCAG AGGTGCTGAG TTTTTGCCCT TCTGAGCAGG GAATCTTTGC TTATCCCTTT GACCAAGGAT CTΪTGCTGCA AAGGCTGGGT ATCGGCTGTG CTCAGCAAAG CGTCAACTCG TGCAAGAACT TAGCAGGAAT AGTTCTGGCT AAGGTTAGGA GGCTGCCACC AAAGTCTCTT

TTTTGTTCCT CTGCTTCTCC CGTTTGCCTC CTTATCATGA GATCTTTTTG CTAAGCTGGC AGAAAGATTG CATAGTCAGT GCTTCCAGCT CTGCTCCCAC CTGATCCTGC ACTGTCCTCT GGTCCCTGAA TGAATGAACT CTGATACCCA ATCTTGTCTC GAGCCTTCTC TATGCCACTC ATGGCTCCTC TTCTGCTCTT TCCATCTTTT TGCTGAGAGT TCTGAGCTCT GTACTTCCTC TTGGCCCATC TCACTTCCTG AAACACCCCT GAAGAGGGTT GCTTATCTTG ATGGAACTCA AAAAGCCAAA AAGCTGCAGG CAGAGGCGTT GAGGACATCT GTTTGGGGAA CTAAGAGCAG CAGCACTTTC AGATTCAGTC CATATAGAGC TGTCCTACAG CATTCTGGAA ACTTGAGGAT GTGCGGTGCA TAAAGGGGCT GGAAGTGACC CACCTGTGAT GAGCCCTTTC TAAGGAGAAG GGTTTCCAAG AGATCACCCC ACCAGAAAAG GGTAGGAATG AGCAAGTTGG GAATTTTAGA CTGTCACTGC

ACATGGACCT CTGGGAAGAC GTCTGGCGAG AGCTAGGCCC ACTGGCCCTA CAGACGGATC TTGCTGGCTC ACCTGTCCCT GTGGAGGTTC CCCTGGGAAG GCAAGATGCC CAACAACAGC ACTGCTCTGT CATTGGCCAA TGTTACCTAC ATCACCATGG AAATTTTCAT TGGACTCTGC GCCATAGTGG GCAACGTGCT GGTCATCTGC GTGGTCAAGC TGAACCCCAG CCTGCAGACC ACCACCTTCT ATTTCATTGT CTCTCTAGCC CTGGCTGACA TTGCTGTTGG GGTGCTGGTC ATGCCTTTGG CCATTGTTGT CAGCCTGGGC ATCACAATCC ACTTCTACAG CTGCCTTTTT ATGACTTOCC TACTGCTTAT CTTTACCCAC GCCTCCATCA TGTCCTTGCT GGCCATCGCT GTGGACCGAT ACTTGCGGGT CAAGCTTACC GTCAGGTAGC CTGCGGCGTG GGGTGGGCAG CAATTGAGGC AGCTGGGAAA TGAGGCTACA AAGCCAGAGCS CTGCTGAATT TTATTTTGGA

CTGTACATAT TTAGATGCTT AAGGTAAAAA TGATAAAGCC CTCAAGCCAC TGTGTGGGTT GGGTCCAAGT GTTCCTTGCT GCTGCCTCTC TAACACGCCT GGTTAAAATA ATCCCTTTGG ATGGTGCTGA GAAGCACCTG AACCAAGTGG GTCCCCAAAT AACTATGGCG TGCAAGTGTC TGGTTCCCAG AAGTTGGTGA CTAGGTAAGC GACTCAGGGA GAGGGGCTGA TTCCCAGACA GTCGCCTGTT CCTGCTGGGA TGGGGCTGAG GCTTGGGGAA TGTGGGCAGG AGGATATGCC ATTTGATTCT GTTGCACACG TTCTTTTCCC TTCTTTCTGT ATGTCTGGTC ATTCTGCTAT TCTGTCGTTC CTCACATAGG TTGGACATTG GCCGGCTGCC AGCATAAGTG CCAGTGTGAT TTTGCTAGGG TGTGAGCTGA GAAAGAGAGG TGGAGGCTAA GCAGGTGTGA TGCTTCTCAG AGGTGCTGAG TTTTTGCCCT TCTGAGCAGG GAATCTTTGC TTATCCCTTT GACCAAGGAT CTTTGCTCCA

AAGGCTGGGT ATCGGCTGTG CTCAGCAAAG CGTCAACTCG TGCAAGAACT TAGCAGGAAT AGTTCTGGCT AAGGTTAGGA GGCTGCCACC AAAGTCTCTT TTTTGTTCCT CTGCTTCTCC CGTTTGCCTC CTTATCATGA GATCTTTTTG CTAAGCTGGC AGAAAGATTG CATAATCAGT GCTTCCAGCT CCGCTCCCAC CTGATCCTGC ACTGTCCTCT GGTCCCTGAA TGAATGAACT CTGATACCCA ATCTTGTCTC GAGCCTTCTC TATGCCACTC ATGGCTCCTC TTCTGCTCTT TCCATCTTTT TGCTGAGAGT TACTGAGCTC TGTACTTCCT CTTGGCCCAT CTCACTTCCT GAAACACCCC TGAAGAGGGT TGCTTATCTT GATGGAACTC AAAAAGCCAA AAAGCTGCAG GCAGAGGCGT TGAGGACATC TGTTTGGGGA ACTAAGAGCA GCAGCACTTT CAGATTCAGT CCATATAGAG CTGTCCTACA GCATTCTGGA AACTTGAGGA TGTGCGGTGC ATAAAGGGGC TGGAAGTGAC

CCACCTGTGA TGAGCCCTTT CTAAGGAGAA GGGTTTCCAA GAGATCACCC CACCAGAAAA GGGTAGGAAT GAGCAAGTTG GGAATTTTAG ACTGTCACTG CACATGGACC TCTGGGAAGA CGTCTGGCGA GAGCTAGGCC CACTGGCCCT ACAGACGGAT CTTGCTGGCT CACCTGTCCC TGTGGAGGTT CCCCTGGGAA GGCAAGATGC CCAACAACAG CACTGCTCTG CGAATTCGGG GGACATCTGT TTGGGGAACT AAGAGCAGCA GCACTTTCAG ATTCAGTCCA TATAGAGCTG TCCTACAGCA TTCTGGAAAC TTGAGGATGT GCGGTGCATA AACGGGCTGG AAGTGACCCA CCTGTGATGA GCCCTTTCTA AGGAGAAGGG TTTCCAAGAG ATCACCCCAC CAGAAAAGGG TAGGAATGAG CAAGTTGGGA ATTTTAGACT GTCACTGCAC ATGGACCTCT GGGAAGACGT CTGGCGAGAG CTAGGCCCAC TGGCCCTACA GACGGATCTT GCTGGCTCAC CTGTCCCTGT

GGAGGTTCCC CTGGGAAGGC AAGATGCCCA ACAACAGCAC TGCTCTGTCA TTGGCCAATG TTACCTACAT CACCATGGAA ATTTTCATTG GACTCTGCGC CATAGTGGGC AACGTGCTGG TCATCTGCGT GGTCAAGCTG AACCCCAGCC TGGAGACCAC CACCTTCTAT TTCATTGTCT CTCTAGCCCT GGCTGACATT GCTGTTGGGG TGCTGGTCAT GCCTTTGGCC ATTGTTGTCA GCCTGGGCAT CACAATCCAC TTCTACAGCT GCCTTTTTAT GACTTGCCTA CTGCTTATCT TTACCCACGC CTCCATCATG TCCTTGCTGG CCATCGCTGT GGACCGATAC TTGCGGGTCA AGCTTACCGT CAGATACAAG AGGGTCACCA CTCACAGAAG AATATGGCTG GCCCTGGGCC TTTGCTGGCT GGTGTCATTC CTGGTGGGAT TGACCCCCAT GTTTGGCTGG AACATGAAAC TGACCTCAGA GTACCACAGA AATGTCACCT TCCTTTCATG CCAATTTGTT TCCGTCATGA GGATGGACTA

CATGGTATAC TTCAGCTTCC TCACCTGGAT TTTCATCCCC CTGGTTGTCA TGTGCGCCAT CTATCTTGAC ATCTTTTACA TCATTCGGAA CAAACTCAGT CTGAACTTAT CTAACTCCAA AGAGACAGGT GCATTTTATG GACGGGAGTT CAAGACGGCT AAGTCCTTGT TTCTGGTTCT TTTCTTGTTT GCTCTGTCAT GGCTGCCTTT ATCTCTCATC AACTGCATCA TCTACTTTAA TGGTGAGGTA CCACAGCTTG TGCTGTACAT GGGCATCCTG CTGTCCCATG CCAACTCCAT GATGAACCCT ATCGTCTATG CCTATAAAAT AAAGAAGTTC AAGGAAACCT ACCTTTTGAT CCTCAAAGCC TGTGTGGTCT GCCATCCCTC TGATTCTTTG GACACAAGCA TTGAGAAGAA TTCTGAGTAG TTATCCATCA GAGATGACTC TGTCTCATTG ACCTTCAGAT TCCCCATCAA CAAACACTTG AGGGCCTGTA TGCCTGGGCC AAGGGATTTT TACATCCTTG ATTACTTCCA CTGAGGTGGG

AGCATCTCCA GTGCTCCCCA ATTATATCTC CCCCACTCCA CTACTCTCTT CCTCCACTTC ATTTTTCCTT TGTCCTTTCT CTCTAATTCA GTGTTTTGGA GGCCTGACTT GGGGACAACG TATTATTGAT ATTATTGTCT GTTTTCCTTC TTCCCAATAG AAGAATAAGT CATGGAGCCT GAAGGGTGCC TAGTTGACTT ACTGACAAAA GGCTCTAGTT GGGCTGAACA TGTGTGTGGT GGTGACTCAT TTCCATGCCA TTGTGGAATT GAGCAGAGAA CCTGCTCTCG GAGGATGCCT AGGAGATGTT GGGAACAGAA GAAATAAACT GAGTTTAAGG GGGACTTAAA CTGCTGAATT C AAATGATAGA CCGTCAATAA TTTGTTAAAT GCTTTTTAAA ATGAATGCTT TAAGCCGGGT GCAGTGCCTC ACATCTGTAA TCCCAGCACT TTGGAGCCGA GCGGGTGGAT TGTGTGAGGT CAGGAGTTCG AGACCAACCT GGCCAACATG GCAAAACCTC ACTCTCTACC AAAAATACAA AAATTAGCCA

GGCATGGTGG CAGGCACCTG TGATCCCAGC TACTCAGGAG GCTGAGACAG GAGAATCGCT TGAACCCGGG AGGCAAGGTT GCAGTGAGCC AAGATTACGC CATTGTACTC CAGCCTGGGT GACAGAGAGA GACTCCGTCT CAAAAAAAAA AAAAAAAAAA AAAAAATTAC GCTTCAAACA CATGATCTCT CACCACTGTT GAATTTTCTT TCTATGAGCC CAGGAGGGCC TCTCAGAGAG GAAAGCTCCT AGGTCTTCCT TTCCCTCTGC AAACTCCCTG CCTTGAAGGT TCAGAAGGAC TGTGCGTGCT CGTTGCATCC TTTGCAAGTG TCCAAACCCT GATCCCAGCT GTGCTTAGGG GTTCCTGCAA ACCTTTTCCA GGTGTTAATT ACCTCCCACT TCATTTCCTG TTTACCAACT CAGCTTTTTG TTTTAGTGTG TTTGAATTCC CTGAACTGAC CGTTGTCTGA TCTCCACCTC CCAACTGAAT TAGGGGAGCT GGGCTTCTGG AAACCCAGGT GCCGGGTGTT GCAGAGTGGC TGAAAGCTGG

GATGTGGCAG ATCCGTGGCT ACATTCATGC ACACACACAC ACCCACATAC CCACACATGC ACACACACAC ACACACCCGC ACTCACACAC TTGGACATGC ATAGACCACA GCTTTCCACA CCCTTCCTAG ACAGGGGTCA CTTGGTATCC TGGAGAGAGT GTGAAGTCCT GGAATGGAAA GAGGGGGGAT TAAGCCCCAC CTCTAGCCAT GGGACTGAGA CAAGTCACCA CCAACCCATC TGCGCCTTGT TTACCTCCTC TGTGAGGCAA GCACAGAGCC CATGCCTGCC CCCCTGGATG GGAGTGATGT GAAACTTGAA GGGCGGTCAG AGCAAGGGTC GGGAATGGAA GGCCCTTGGG AAAAAAGGCC CTTTCAACTA GGGGCACAGA GGAGGCCCTG GGCTGAGAAC TTGACAGCAC CTTGTAATTG GTAAGCCAAG CCCGAAGGGA CTGGAAATAC TCAGATGTGT CTGTCTCCCT TATTAGGTTC AAAGTCCCTC AAGACCCTGT CTCCATCACA GTGCTCCAGT CCAGACCCCT CCTCTGAGCT CCAGACCCTG CTGGACCCAA CCAGCCCTAT GGGGTCGCAT CCCCACCTGC CTGGAATTCT CCAAAGAACC TCCCCTTTAA CAGTTCCAGC CTTTAACAGT TCCAGTCTAA ACACATGACC TTTCTCCTCT AAATCAGCCC CCCATCTCTG CCTTTGCAGG AGATGGAAGC CATGACACCT GCCTCGCCCC TGTCCTCACC CCATCCATGT CCAATCAAGC ACTAGGCATG TCAGGTTTAC CCTCTAAACT CCTCTGGAAT CCAGTCTCTC AGTCTCCATC ATCCCAGGTC GAAGCTAATG GGCTAACTGG TCCTTGCTTC CACTCTACCC CCACTGCAGT CCTGACTTCC TGAGCAGCAG CCAGGGCCTA ATCGATATTC ACACCAAGCG CCAACCTGAC TGAGATATCC TCCTGCACCA TCATCCCTCC

ACCCTGTTTA GTTCTGCTCA CCCTCAGTGT TCTCATCAAT AATCCACTCC CCTCACAGGC GCGTTTGGGA CCCCATGTTC TATGCTCTCA CAGGACCTTT TGCTTGATTT TTCACTGTAC TTAGGTCAGT TTGCAGTTAT TAAGTGACTG AGCAATGTCT GGCTTCTCCA GTAGACTGTC AGCTCCTAGC CATTGTATAC CTAGCACCGC TGTGTGGGAG CACGTGACAA ACGTCCAGTG AGTCAGGGAC TCAGCAGTCT CCATTTCTCC GCCCTGCTGG AGAATGCGTG TATTTGGCAA TCCCCAGCCC CTGTGCCATC TAACCATCTT TTCTTCTCTG TTCAGCCCAG GTGTGGCCTC ACTCACATCC CACTCTGAGT CCAAATGTTC TCTCCCTGGA AGATATCAAT GTTTCTGTCT GTTCGTGAGG ACTCCGTGCC CACCACGGCC TCTTTCAGGT GAGTCAAAGG GATTCCTCAG TTCACTAGTT AGGGGAGGTG GGCAGACACC CTGGAGAACT CCCTGGAAAG CTCAACTCTC ATGCCCCGGA

CAACAGTTGA AGGAACCATG GTGATGTTAA GCCCAAAGAC AAAACCTCTC AGGTGTCCAA GTCCCTGTTG GAATCTTGGG AGCAGAGGGA ATGTTCTGTG GTCTAGAGGA AGAGGGGCTC AGGGAGGAGA AGGGCACATT CCTGGTTGTT ATATGTTTCT ATCTATCCCA GATGAACTTG GAAGTGAAGG GAAGAGAGTT AAACATTAAA GTAAATACCC AGTGGATCAG ACAGCAATGT GCCAGATTGC CTTGGAAACA AAATATCTCC AACACATGGC TGACATTTGG TGGGAGATCA GAACACCCTA AAGAGAGAAT TTAAGGGGAG GGGGAGGAGG ACCTGAGCCA GAGTAGAAGC AGAGGATAGG GAGATCTGTT CTTGGGGACA GCATTTGCAA GAAACAAGGC TGAGGGGTCC ACTCCAACCT CTCCACCCTG CTGCAGGTGC TGCCTATGAT GAAGATGAGC AGATGGCCAT CTCAGCTGGG GCCACAGTGC ACTGGACCTA TAGTTTCCAA TTCCGCACTC AGCAGGCATC

TTTCTGATGA TCCGATGGCT TCTCAGAGCC AGGGATGGGC CAGGATCCAT CCCCTTGGCT ACTGTCTTGC TGAGAAATTT ATAAGCAGCA TCTGGTGCTA TACTTTGGTC TCTAGTGAGT TAGCTCATGA AAGATGATAG ACTCTCCAAG CCAGGGGTAT GCAGGAAATG GGTTTTCTGT AGCTACAGAA ATGGGGTTGA GGGTTGGACC AAGGGACTAC CCAGGGGAAG TCTTACCTTC AGAGGACTCT GGAAAGGAGG CTGCAAGTTT TCATGGGTCA AGAATTCAGA GCCCAGTAGA GACAGCTTAT CTCTGTTCCA AGATGTCTGG GGCCTTGGTT GGAAGATTCA AAGGCTAGGA AACCAGGAGC CACCAAAAGC GTAACTGGGG CCAGAGGATC CACTTTCAAG GTGGCAAGTT GGTTCCCCCC ATGTGGCTGC TTGAGTATCC TCACATGGCG GCTCACATCC TTCCAAGTAA GCAATGCAAA AGGCCAAGAA AGATGCTGCA AAGATGTTAT GACCTAGCCT CAGAAATCAC ACACCATCCC

TGCCACCATT AGTAAGAAGT CCAGCCCACG TCCAGGAGAA GAGGAAGCAG ATTCCTCCTT TTGAAATGAA GAATATCAAG TAATTCGGGG GGCATATGAA AGCCACCACA CACCACAGGG ATCTTTTTAG AGCATACTTC TTATACCATC ACTGTAGTTC CTTAAGACTC AGGGGCAAAG CCTCACTTCC TTAGCACCCA GTGAAGACCA CGCTTACTCC CTCACTCAAC CTCTTGCTAC TTCCCACCTC TCCTGTCCAA CATCTAGTGT CACTTTCCAG AACATACCAA CAGCTTCCCC AGTTCTGTGC CTCTGCTCAG GCTGTTCCCC CTGCCTGGTC CACTTGTCCT CCTTCTTGTC CGGTCAAAAT GCTTCTTATC CTTCAAGACC CAGCTCTAGA GTCACCTCCA ACCCCTTACC CACCAGCCCC CTCTCCAAGT CTGTGTCCCA CAACCCCCCT GCTCCCTCCA GGGCACCCTC CACCCTCTGG GCCACAGTTG TCAGGAGTCA GGCAGGGCAG GGGCCGGGTG GTGTCTTCTT TGTGTTCTTG

CACTCAGGGC AGAGCTCAGC ACAGAGCAGA CGCTCAAAAA ACATTTAAAG GATAGAAGCA TTGATTTGTG GGTCCCCCAG TCTGGCTCCA GGATGCCAGC CAGCTGCTCC TAGAAGCAAA CGGACTTTTC CTGGGAAATC CCAGAGGTGA TGATCAGTAA TCTCTCCCGT GACTCGTAGT TCAGCTCTTC CTCCATGAGC CTGACTATCA GTGGACCTTC CAGAAAGAGC CCCTTTTCCT TCTCTCACCC ACAGCACAGG GCACTGGGAA AATGCCCAAT GAGTCCTGCC TCTGGGTTGT GCTTTGGACT TTTCAGTGTG TCTCGCATCC ACTCTTCAAC TTGAATGTTG CAACAGCCAT GAAAAAAGAA ATGCAAAGCG ATTCAGGATG AGAGCAATAC CCTACTCCAA AGAAGGCAAC ATAGAAGCTC AGAGAGATCA AGCAATTTGC CCAAGACCAC ACAGCTAGGA GTGGAACTCA TGGCTGTCCA AGCCCCATGC CTCTGCTGAA GGTAGAGATG AATTACAGCA ACAAGTCTAG AAAGGTGCCT

GCCCTATGGT CTGTGAGTCT TGCCTAAGAA TGAAAGAGGA GCCAGTGGGT TAAAGATGAG GTCACCAACA ACGGTGGTGT TGGAGTTTAC CACTGATAAT AAGGQTGCAA AATGTAAATT ACTAATGTTT ATTGAGCCTA GTGCAGTGCG TGGGGCATTT TGCACATTGT CTCTGATCCC TATGACAACC CTGAGAGGTA GTGGTTTTAA CTGCCATGTT ACAGGTGAGG TCATTGTGGT TCAAGGACGT TAAGTAACTT CCCCAGCGTG ACACGGCTTA TAAGTAAGGC AGCCAGGATG TGAACCCAGT AGGACTATCT GGCTGCAAAG TCCCCACCCC CCTCGCCATC TGTATCCTCC AATCACTTCA GTGCTTTGCT GCATAGAAGG TAACGGAAAT CACGATGCCA CAGACTGTCC AGGAAGACAG AAACTAGGCA GATGGGCTGG CCATGGTCTC CAAGCCAGAC TGGAATCTCC AGGTCTGGAA TGATATCATT TTTCTCTTTT AATAAATTAA CTCACCCACC ACACGGCTTT GAGAGGCTCA

AAGTTGACCA ACTCCCTTGG GAGGGCCCCG GTTGATAAGG AAGGAACGTG AATCCTCCCA TCACGGAAGC TTCAAGGAGG TCAAGGGTCC AACACTTGAG ATTGTTAGTG CTGTTGGTGG ATACTGGCCA AGGAAATATC CCAGTGGAGC CTCGAGATGA AGAACATGAG GCCCCCGTTT AGAACCAAGG ATCAGAGGGG GCTCTGTAAG ACCCAGGGGA GTCAGGTGCA CTGGAGCGCG GGCATGCAGA AAACAGCCTG AGCTCCACCT CGGCTTCTCC TTGTCCTGGC TGGTTGTCCT TAACCCCTGT CTCCTTCTGG ACCAGTTTTT GTCCTTCCCT TGTGACCGCT GAGGGGTAAC AGCCTCTTTC CACTTTCTTT CAGCGCCGAC ATGCTCAATG TCACCTTGCA AGGGCCCACT CTTAACGGGA CCTTTGCCCA GAGCAAATGC CCCCAAGTGG AGTGGCTGGG CTGGCTCAAC ACCATCCAGC CCCCCTTCCT CTGGGTGCTG TTCGTGCTGG CCACCCTAGA GAACATCTTT

GTCCTCAGCG TCTTCTGCCT GCACAAGAGC AGCTGCACGG TGGCAGAGAT CTACCTGGGG AACCTGGCCG CAGCAGACCT GATCCTGGCC TGCGGGCTGC CCTTCTGGGC CATCACCATC TCCAACAACT TCGACTGGCT CTTTGGGGAG ACGCTCTGCC GCGTGGTGAA TGCCATTATC TCCATGAACC TGTACAGCAG CATCTGTTTC CTGATGCTGG TGAGCATCGA CCGCTACCTG GCCCTGGTGA AAACCATGTC CATGGGCCGG ATGCGCGGCG TGCGCTGGGC CAAGCTCTAC AGCTTGGTGA TCTGGGGGTG TACGCTGCTC CTGAGCTCAC CCATGCTGGT GTTCCGGACC ATGAAGGAGT ACAGCGATGA GGGCCACAAC GTCACCGCTT GTGTCATCAG CTACCCATCC CTCATCTGGG AAGTGTTCAC CAACATGCTC CTGAATGTCG TGGGCTTCCT GCTGCCCCTG AGTGTCATCA CCTTCTGCAC GATGCAGATC ATGCAGGTGC TGCGGAACAA CGAGATGCAG AAGTTCAAGG

AGATCCAGAC GGAGAGGAGG GCCACGGTGC TAGTCCTGGT TGTGCTGCTG CTATTCATCA TCTGCTGGCT GCCCTTCCAG ATCAGCACCT TCCTGGATAC GCTGCATCGC CTCGGCATCC TCTCCAGCTG CCAGGACGAG CGCATCATCG ATGTAATCAC ACAGATCGCC TCCTTCATGG CCTACAGCAA CAGCTGCCTC AACCCACTGG TGTACGTGAT CGTGGGCAAG CGCTTCCGAA AGAAGTCTTG GGAGGTGTAC CAGGGAGTGT GCCAGAAAGG GGGCTGCAGG TCAGAACCCA TTCAGATGGA GAACTCCATG GGCACACTGC GGACCTCCAT CTCCGTGGAA CGCCAGATTC ACAAACTGCA GGACTGGGCA GGGAGCAGAC AGTGAGCAAA CGCCAGCAGG GCTGCTGTGA ATTTGTGTAA GGATTGAGGG ACAGTTGCTT TTCAGCATGG GCCCAGGAAT GCCAAGGAGA CATCTATGCA CGACCTTGGG AAATGAGTTG ATGTCTCCGG TAAAACACCG

GAGACTAATT CCTGCCCTGC CCAATTTTGC AGGGAGCATG GCTGTGAGGA TGGGGTGAAC TCACGCACAG CCAAGGACTC CAAAATCACA ACAGCATTAC TGTTCTTATT TGCTGCCACA CCTGAGCCAG CCTGCTCCTT CCCAGGAGTG GAGGAGGCCT GGGGGCAGGG AGAGGAGTGA CTGAGCTTCC CTCCCGTGTG TTCTCCGTCC CTGCCCCAGC AAGACAACTT AGATCTCCAG GAGAACTGCC ATCCAGCTTT GGTGCAATGG CTGAGTGCAC AAGTGAGTTG TTGCCCTGGG TTTCTTTAAT CTATTCAGCT AGAACTTTGA AGGACAATTT CTTGCATTAA TAAAGGTTAA GCCCTGAGGG GTCCCTGATA ACAACCTGGA GACCAGGATT TTATGGCTCC CCTCACTGAT GGACAAGGAG GTCTGTGCCA AAGAAGAATC CAATAAGCAC ATATTGAGCA CTTGCTGTAT ATGCAGTATT GAGCACTGTA GGCAAGAGGG AAGAAAGAGA AGGAGCCATC TCCATCTTGA AGGAACTCAA

AGACTCAAGT GGGAACGACT GGGCACTGCC ACCACCAGAA AGCTGTTCGA TGAGACGGTC GAGCAGGGTG CTGTGGGTGA TATGGACAGC AGAAGGGGGA GCCAGGTTCC AGCTCACCAA TACTATTGCA CACCACCTGT CCTGCCTC GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG GCTCCGAGGA GGGGTGGGGA CGGTGGTGAC GGTGGGGACA TCAGGCTGCC CCGCAGTACC AGGGAGCGAC TGAAGTGCCC ATGCCGCTTG CTCCGGAGAA GGTGGGTGCC GGGCAGGGGC TGCTCCAGCC GCCTCACCTC TGCTGGGAGG ACAAACTGTC CCAGCACAGA GGGAGGGAGG GAGGGCAGGC AGCGGGGAGA AGTTTCCCTG TGGTCGTGGG GAGTT GAGCTCTTCA ATATTTTAGT GAAAGCTATA GATGAGGCTC CATAGGGGAT AAAGCACAGA CACACCTTTT CAGAGGGCTT GTGGACTCTG

GGCAGCCTGT CCATAGACCT CTGTCCCCAA CTGGCAAGTC AGGAAACTCC AGATTAAGGA GCCCCAATGT GGTTGAACAG CCAGGTGCAC AGATGAGTCA ACCACACAGC CAGGCCAGGG AGGGCCTTCA CTCAAGAGCC TACAGCCAGT TCACAGCCAA GCCAGGGCTA GCGCCAGGCC ACCCATAAAC TGATCTGAGA CTCTGTTTCC CTGTCTCCAT GATGATGGGA TCAGGCTTGA TTGCTGGTTT GTAGGCTTGT TATGAATCAA GTCACAGGGA AGAGGAGCTG ATGGGCTGGG GGGACGTCCT CTGGCCCTCC TGTCTCTTCC CCAGATCCAC TGGGCCCACT CTTATCTGTT CTCTTCTGAA GGAAGGGTTT TAAGGCTTCA AAAAAAAATG TTTTGAAAGT CCCTGCCCTT TCCAGCTCCT ACCGTCTCAG CCCTGGGAGT GTAAAGTGCT GCAGATAGTT AGTAAGTCTT TGAGCAAAAC TGAGAAAGCC AGCCTGAGCC TTGACATGGG AGAAACCTCC GCCATACATC TCCGAAGAAA

CGGCCGCGTG TCTCAGGGGA GCGCAAACAC CCGTACCCAG GAAACAGGAC AGCTTCTGCC ACTGTCGCCC TTGGGAGCCG TACGTGGCAT GACAAAGAAA TCCCAGGACT CCGCCTGCCC ACCTGGCCAC CCTCTGTTTA CACCTTCCGC GTAAACGCCC ACTGTTTACA TCCAAAACTC AGACACAAAA TAACCACCTC AAGAAGATAA ATAATGATAA GAAATAAATG TTACGCGAGG CAAATTTATT CACATGGGGC TTCCCAGGCC ACTTTGTGGT CAGCCGGGAG GGACGTTTTT GCCGTCCCAC GACTCCAACG GGCAGCCGGG CCTACGCAAA CATGGAAATC TTCCAAGAGC CTCCCTGGCC CCCAGGGCTC AGAGGGTGGC AGAGCGGAGA GCGAAGGTGG CCGCAGCCTT CCCGGCCCCA CAGCCAGCCT GGCTCCAGCT GGGCAGGAGT GCAGAGCTCA GCTGGAGGCG AGGGGGAAGT GCCCAGGAGG CTGATGACAT CACTACCCAG CCCTTCAAAG ATGAGCTGTT

CCCGCCGCCA CTCCAGCTCT GGCTTCTGGG CTCCGAGGAG GGGTGGGGAC GGTGGTGACG GTGGGGACAT CAGGCTGCCC CGCAGTACCA GGGAGCGACT GAAGTGCCCA TGCCGCTTGC TCCGGAGAAG GTGGGTGCCG GGCAGGGGCT GCTCCAGCCG CCTCACCTCT GCTGGGAGGA CAAACTGTCC CAGCACAGAG GGAGGGAGGG AGGGCAGGCA GCGGGGAGAA GTTTCCCTGT GGTCGTGGGG AGTTGGGAAA AGTTCCCTTC CTTCCGGAGG GAGG CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG TCTCCGGTAA AACACCGGAG ACTAATTCCT GCCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG

GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC AGGAGTGGAG GAGGCCTGGG GGGAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC TCCGTCCCTG CCCCAGCAAG ACAACTTAGA TCTCCAGGAG AACTGCCATC CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT CTTTAATCTA TTCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGAGGTC TGTGCCAAAG AAGAATCCAA TAAGCACATA TTGAGCACTT GCTGTATATG CAGTATTGAG CACTGTAGGC AAGACCCAAG AAAGAGAAGG AGCCATCTCC ATCTTGAAGG AACTCAAAGA CTCAAGTGGG AACGACTGGG CACTGCCACC ACCAGAAAGC

TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC ACAACCACCT GTCCCTGCCT CAGTTCCCTT TTATGTAACA TGAAGTCGTT GTGAGGGTTA AAGGCAGTAA CAGGTATAAA GTACTTAGAA AAGCAAAGGG TGCTACGTAC ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT ACTATAAGGA AAAGACACTG AGGTCTAGAA ATAGCTCCGT GGAGCAGAAT CAGTATTGGG AGCCGGTGGC GGTGTGAAGC ACCAGTGTCT GGCACACAGT AGGTGCTCAT TGGCTCCCTT CCACCTGTCA TTCCCACCAC CCTGAGGCCC CAACCGCCAC ACACACAGGA GCATTTGGAG AGAAGGCCAT GTCTTCAAAG TCTGATTTGT GATGAGGCAG AGGAAGATAT TTCTAATCGG TCTTGCCCAG AGGATCACAG TGCTGAGACC CCCCACCACC AGCCGGTACC TGGGAAGGGG GAGAGTGCAG

GCCTGCTCAG GGACTGTTCC TGTCTCAGCA ACCAAGGGAT TGTTCCTGTC AATCAATGGT TTATTGGAAG GTGGCCCAGT ATGAGCCCTA GAAGAGTGTG AAAAGGAATG GCAATGGTGT TCACCATCGG CAGTGCCAGG GCAGCACTCA TTCACTTGAT AAATGAATAT TTATTAGCTG GTTGGAGAGC TAGAACCTGG AGAGCTAGAA CCTGGAGAAC TAGAACCTGG AGGGCTAGAA CCTGGAGAGG CTAGAACCAA GAAGGGCTAG AACCTGGAGG GGCTAGAACC TAGAGAAGCT AAAACCTGAG CTAGAAGCTG GAGGACTAGA ACCTGGAGGG CTGGAATCTG AAGGGCTAGA ACCTGGAGGG CTGGAATCTG GAGAGCTAGA ACCTGGAGGG CTAGAACCTG GAGGGCTAGA ACCTAGAAGG GCTAGAACCT GGAGGGCTGG AATCTGGAGA GCTAGAACCT GGAGGGCTAG AACCTGGAGG GCTAGAACCT AGAAGGGCTA GAACCTGGAG

GGCTAGAACC TGGCAGGTTA GAACCTAGAA GGGCTAGAAC CTGGAGAGCC AGAACCTGGA GGGCTAGAAC CTGGAAGGGC TAGAACCTGT AGAGCTAGAA CATGGAGAGC TAGAACCCGG CAGGCTAGAA CCTGGCAAGC TAGAACCTGG AGGGAATGAA CCTGGAGGGC TAGAACCTGG AGAATGAGAA AAATTTACAT GGCAAAGAGC CCATAAATCC TGACCAATCC AACTCTGAAT TTTAAAGCAA AAGCGTGAAA AAAAAGATTC CCTCCTTACC CCCAACCCAC TCTTTTTTCC CACCACCCAC TCTCCTCTGC CTCAGTAAGT ATCTGGAGGA AGAAAACAGG TGAAAGAAGA AGTAAAAACC ATTTAGTATT AGTATTAGAA TGAAGTCAAA CTGTGCCACA CATGGTGAAT GAAAAAAAAA AAAAAGAGGC TGTGTTTTGT CACACAGGGC AGTCATTCAG CACCAGAGCA CGTGATGGTC TGAGACTCTC TTAGGAGCAG AGCTCTGCCG CAATGGCCAT

GTGGGGATCC ACACCTGGTC TGAGGGGCAA CTGAGTCTGC GGGAGAAGAG CGGCCCTATG CATGGTGTAG ATGCCCTGAT AAAGAACATC TGTCCTGTGA AAGACTCAAT GAGCTGTTAT GTTGTAAACA GGAAGCATTT CACATCCAAA CGAGAAAATC ATGTAAACAT GTGTCTTTTC TGTAGAGCAT AATAAATGGA TGAGGTTTTT GCAAAAAAAA AAAAAAAAA AAATGATAGA CCGTCAATAA TTTGTTAAAT GCTTTTTAAA ATGAATGCTT TAAGCCGGGT GCAGTGCCTC ACATCTGTAA TCCCAGCACT TTGGAGCCGA GCGGGTGGAT TGTGTGAGGT CAGGAGTTCG AGACCAACCT GGCCAACATG GCAAAACCTC ACTCTCTACC AAAAATACAA AAATTAGCCA GGCATGGTGG CAGGCACCTG TGATCCCAGC TACTCAGGAG GCTGAGACAG GAGAATCGCT TGAACCCGGG AGGCAAGGTT GCAGTGAGCC AAGATTACGC CATTGTACTC CAGCCTGGGT GACAGAGAGA GACTCCGTCT CAAAAAAAAA AAAAAAAAAA AAAAAATTAC GCTTCAAACA CATGATCTCT CACCACTGTT GAATTTTCTT TCTATGAGCC CAGGAGGGCC TCTCAGAGAG GAAAGCTCCT AGGTCTTCCT TTCCCTCTGC AAACTCCCTG CCTTGAAGGT TCAGAAGGAC TGTGCGTGCT CGTTGCATCC TTTGCAAGTG TCCAAACCCT GATCCCAGCT GTGCTTAGGG GTTCCTGCAA ACCTTTTCCA GGTGTTAATT ACCTCCCACT TCATTTCCTG TTTACCAACT CAGCTTTTTG TTTTAGTGTG TTTGAATTCC CTGAACTGAC CGTTGTCTGA TCTCCACCTC CCAACTGAAT TAGGGGAGCT GGGCTTCTGG AAACCCAGGT GCCGGGTGTT GCAGAGTGGC TGAAAGCTGG GATGTGGCAG

ATCCGTGGCT ACATTCATGC ACACACACAC ACCCACATAC CCACACATGC ACACACACAC ACACACCCGC ACTCACACAC TTGGACATGC ATAGACCACA GCTTTCCACA CCCTTCCTAG ACAGGGGTCA CTTGGTATCC TGGAGAGAGT GTGAAGTCCT GGAATGGAAA GAGGGGGGAT TAAGCCCCAC CTCTAGCCAT GGGACTGAGA CAAGTCACCA CCAACCCATC TGCGCCTTGT TTACCTCCTC TGTGAGGCAA GCACAGAGCC CATGCCTGCC CCCCTGGATG GGAGTGATGT GAAACTTGAA GGGCGGTCAG AGCAAGGGTC GGGAATGGAA GGCCCTTGGG AAAAAAGGCC CTTTCAACTA GGGGCACAGA GGAGGCCCTG GGCTGAGAAC TTGACAGCAC CTTGTAATTG GTAAGCCAAG CCCGAAGGGA CTGGAAATAC TCAGATGTGT CTGTCTCCCT TATTAGGTTC AAAGTCCCTC AAGACCCTGT CTCCATCACA GTGCTCCAGT CCAGACCCCT CCTCTGAGCT

CCAGACCCTG CTGGACCCAA CCAGCCCTAT GGGGTCGCAT CCCCACCTGC CTGGAATTCT CCAAAGAACC TCCCCTTTAA CAGTTCCAGC CTTTAACAGT TCCAGTCTAA ACACATGACC TTTCTCCTCT AAATCAGCCC CCCATCTCTG CCTTTGCAGG AGATGGAAGC CATGACACCT GCCTCGCCCC TGTCCTCACC CCATCCATGT CCAATCAAGC ACTAGGCATG TCAGGTTTAC CCTCTAAACT CCTCTGGAAT CCAGTCTCTC AGTCTCCATC ATCCCAGGTC GAAGCTAATG GGCTAACTGG TCCTTGCTTC CACTCTACCC CCACTGCAGT CCTGACTTCC TGAGCAGCAG CCAGGGCCTA ATCGATATTC ACACCAAGCG CCAACCTGAC TGAGATATCC TCCTGCACCA TCATCCCTCC ACCCTGTTTA GTTCTGCTCA CCCTCAGTGT TCTCATCAAT AATCCACTCC CCTCACAGGC GCGTTTGGGA CCCCATGTTC TATGCTCTCA CAGGACCTTT TGCTTGATTT TTCACTGTAC

TTAGGTCAGT TTGCAGTTAT TAAGTGACTG AGCAATGTCT GGCTTCTCCA GTAGACTGTC AGCTCCTAGC CATTGTATAC CTAGCACCGC TGTGTGGGAG CACGTGACAA ACGTCCAGTG AGTCAGGGAC TCAGCAGTCT CCATTTCTCC GCCCTGCTGG AGAATGCGTG TATTTGGCAA TCCCCAGCCC CTGTGCCATC TAACCATCTT TTCTTCTCTG TTCAGCCCAG GTGTGGCCTC ACTCACATCC CACTCTGAGT CCAAATGTTC TCTCCCTGGA AGATATCAAT GTTTCTGTCT GTTCGTGAGG ACTCCGTGCC CACCACGGCC TCTTTCAGGT GAGTCAAAGG GATTCCTCAG TTCACTAGTT AGGGGAGGTG GGCAGACACC CTGGAGAACT CCCTGGAAAG CTCAACTCTC ATGCCCCGGA CAACAGTTGA AGGAACCATG GTGATGTTAA GCCCAAAGAC AAAACCTCTC AGGTGTCCAA GTCCCTGTTG GAATCTTGGG AGCAGAGGGA ATGTTCTGTG GTCTAGAGGA AGAGGGGCTC

AGGGAGGAGA AGGGCACATT CCTGGTTGTT ATATGTTTCT ATCTATCCCA GATGAACTTG GAAGTGAAGG GAAGAGAGTT AAACATTAAA GTAAATACCC AGTGGATCAG ACAGCAATGT GCCAGATTGC CTTGGAAACA AAATATCTCC AACACATOGC TGACATTTGG TGGGAGATCA GAACACCCTA AAGAGAGAAT TTAAGGGGAG GGGGAGGAGG ACCTGAGCCA GAGTAGAAGC AGAGGATAGG GAGATCTGTT CTTGGGGACA GCATTTGCAA GAAACAAGGC TGAGGGGTCC ACTCCAACCT CTCCACCCTG CTGCAGGTGC TGCCTATGAT GAAGATGAGC AGATGGCCAT CTCAGCTGGG GCCACAGTGC ACTGGACCTA TAGTTTCCAA TTCCGCACTC AGCAGGCATC TTTCTGATGA TCCGATGGCT TCTCAGAGCC AGGGATGGGC CAGGATCCAT CCCCTTGGCT ACTGTCTTGC TGAGAAATTT ATAAGCAGCA TCTGGTGCTA TACTTTGGTC

TCTAGTGAGT TAGCTCATGA AAGATGATAG ACTCTCCAAG CCAGGGGTAT GCAGGAAATG GGTTTTCTGT AGCTACAGAA ATGGGGTTGA GGGTTGGACC AAGGGACTAC CCAGGGGAAG TCTTACCTTC AGAGGACTCT GGAAAGGAGG CTGCAAGTTT TCATGGGTCA AGAATTCAGA GCCCAGTAGA GACAGCTTAT CTCTGTTCCA AGATGTCTGG GGCCTTGGTT GGAAGATTCA AAGGCTAGGA AACCAGGAGC CACCAAAAGC GTAACTGGGG CCAGAGGATC CACTTTCAAG GTGGCAAGTT GGTTCCCCCC ATGTGGCTGC TTGAGTATCC TCACATGGCG GCTCACATCC TTCCAAGTAA GCAATGCAAA AGGCCAAGAA AGATGCTGCA AAGATGTTAT GACCTAGCCT CAGAAATCAC ACACCATCCC TGCCACCATT AGTAAGAAGT CCAGCCCACG TCCAGGAGAA GAGGAAGCAG ATTCCTCCTT TTGAAATGAA GAATATCAAG TAATTCGGGG GGCATATGAA AGCCACCACA

CACCACAGGG ATCTTTTTAG AGCATACTTC TTATACCATC ACTGTAGTTC CTTAAGACTC AGGGGCAAAG CCTCACTTCC TTAGCACCCA GTGAAGACCA CGCTTACTCC CTCACTCAAC CTCTTGCTAC TTCCCACCTC TCCTGTCCAA CATCTAGTGT CACTTTCCAG AACATACCAA CAGCTTCCCC AGTTCTGTGC CTCTGCTCAG GCTGTTCCCC CTGCCTGGTC CACTTGTCCT CCTTCTTGTC CGGTCAAAAT GCTTCTTATC CTTCAAGACC CAGCTCTAGA GTCACCTCCA ACCCCTTACC CACCAGCCCC CTCTCCAAGT CTGTGTCCCA CAACCCCCCT GCTCCCTCCA GGGCACCCTC CACCCTCTGG GCCACAGTTG TCAGGAGTCA GGCAGGGCAG GGGCCGGGTG GTGTCTTCTT TGTGTTCTTG CACTCAGGGC AGAGCTCAGC ACAGAGCAGA CGCTCAAAAA ACATTTAAAG GATAGAAGCA TTGATTTGTG GGTCCCCCAG TCTGGCTCCA GGATGCCAGC CAGCTGCTCC

TAGAAGCAAA CGGACTTTTC CTGGGAAATC CCAGAGGTGA TGATCAGTAA TCTCTCCCGT GACTCGTAGT TCAGCTCTTC CTCCATGAGC CTGACTATCA GTGGACCTTC CAGAAAGAGC CCCTTTTCCT TCTCTCACCC ACAGCACAGG GCACTGGGAA AATGCCCAAT GAGTCCTGCC TCTGGGTTGT GCTTTGGACT TTTCAGTGTG TCTCGCATCC ACTCTTCAAC TTGAATGTTG C AACAGCCAT GAAAAAAGAA ATGCAAAGCG ATTCAGGATG AGAGCAATAC CCTACTCCAA AGAAGGCAAC ATAGAAGCTC AGAGAGATCA AGCAATTTGC CCAAGACCAC ACAGCTAGGA GTGGAACTCA TGGCTGTCCA AGCCCCATGC CTCTGCTGAA GGTAGAGATG AATTACAGCA ACAAGTCTAG AAAGGTGCCT GCCCTATGGT CTGTGAGTCT TGCCTAAGAA TGAAAGAGGA GCCAGTGGGT TAAAGATGAG GTCACCAACA ACGGTGGTGT TGGAGTTTAC CACTGATAAT AAGGGTGCAA

AATGTAAATT ACTAATGTTT ATTGAGCCTA GTGCAGTGCG TGGGGCATTT TGCACATTGT CTCTGATCCC TATGACAACC CTGAGAGGTA GTGGTTTTAA CTGCCATGTT ACAGGTGAGG TCATTGTGGT TCAAGGACGT TAAGTAACTT CCCCAGCGTG ACACGGCTTA TAAGTAAGGC AGCCAGGATG TGAACCCAGT AGGACTATCT GGCTGCAAAG TCCCCACCCC CCTCGCCATC TGTATCCTCC AATCACTTCA GTGCTTTGCT GCATAGAAGG TAACGGAAAT CACGATGCCA CAGACTGTCC AGGAAGACAG AAACTAGGCA GATGGGCTGG CCATGGTCTC CAAGCCAGAC TGGAATCTCC AGGTCTGGAA TGATATCATT TTTCTCTTTT AATAAATTAA CTCACCCACC ACACGGCTTT GAGAGGCTCA AAGTTGACCA ACTCCCTTGG GAGGGCCCCG GTTGATAAGG AAGGAACGTG AATCCTCCCA TCACGGAAGC TTCAAGGAGG TCAAGGGTCC AACACTTGAG ATTGTTAGTG

CTGTTGGTGG ATACTGGCCA AGGAAATATC CCAGTGGAGC CTCGAGATGA AGAACATGAG GCCCCCGTTT AGAACCAAGG ATCAGAGGGG GCTCTGTAAG ACCCAGGGGA GTCAGGTGCA CTGGAGCGCG GGCATGCAGA AAACAGCCTG AGCTCCACCT CGGCTTCTCC TTGTCCTGGC TGGTTGTCCT TAACCCCTGT CTCCTTCTGG ACCAGTTTTT GTCCTTCCCT TGTGACCGCT GAGGGGTAAC AGCCTCTTTC CACTTTCTTT CAGCGCCGAC ATGCTCAATG TCACCTTGCA AGGGCCCACT CTTAACGGGA CCTTTGCCCA GAGCAAATGC CCCCAAGTGG AGTGGCTGGG CTGGCTCAAC ACCATCCAGC CCCCCTTCCT CTGGGTGCTG TTCGTGCTGG CCACCCTAGA GAACATCTTT GTCCTCAGCG TCTTCTGCCT GCACAAGAGC AGCTGCACGG TGGCAGAGAT CTACCTGGGG AACCTGGCCG CAGCAGACCT GATCCTGGCC TGCGGGCTGC CCTTCTGGGC

CATCACCATC TCCAACAACT TCGACTGGCT CTTTGGGGAG ACGCTCTGCC GCGTGGTGAA TGCCATTATC TCCATGAACC TGTACAGCAG CATCTGTTTC CTGATGCTGG TGAGCATCGA CCGCTACCTG GCCCTGGTGA AAACCATGTC CATGGGCCGG ATGCGCGGCG TGCGCTGGGC CAAGCTCTAC AGCTTGGTGA TCTGGGGGTG TACGCTGCTC CTGAGCTCAC CCATGCTGGT GTTCCGGACC ATGAAGGAGT ACAGCGATGA GGGCCACAAC GTCACCGCTT GTGTCATCAG CTACCCATCC CTCATCTGGG AAGTGTTCAC CAACATGCTC CTGAATGTCG TGGGCTTCCT GCTGCCCCTG AGTGTCATCA CCTTCTGCAC GATGCAGATC ATGCAGGTGC TGCGGAACAA CGAGATGCAG AAGTTCAAGG AGATCCAGAC GGAGAGGAGG GCCACGGTGC TAGTCCTGGT TGTGCTGCTG CTATTCATCA TCTGCTGGCT GCCCTTCCAG ATCAGCACCT TCCTGGATAC GCTGCATCGC

CTCGGCATCC TCTCCAGCTG CCAGGACGAG CGCATCATCG ATGTAATCAC ACAGATCGCC TCCTTCATGG CCTACAGCAA CAGCTGCCTC AACCCACTGG TGTACGTGAT CGTGGGCAAG CGCTTCCGAA AGAAGTCTTG GGAGGTGTAC CAGGGAGTGT GCCAGAAAGG GGGCTGCAGG TCAGAACCCA TTCAGATGGA GAACTCCATG GGCACACTGC GGACCTCCAT CTCCGTGGAA CGCCAGATTC ACAAACTGCA GGACTGGGCA GGGAGCAGAC AGTGAGCAAA CGCCAGCAGG GCTGCTGTGA ATTTGTGTAA GGATTGAGGG ACAGTTGCTT TTCAGCATGG GCCCAGGAAT GCCAAGGAGA CATCTATGCA CGACCTTGGG AAATGAGTTG ATGTCTCCGG TAAAACACCG GAGACTAATT CCTGCCCTGC CCAATTTTGC AGGGAGCATG GCTGTGAGGA TGGGGTGAAC TCACGCACAG CCAAGGACTC CAAAATCACA ACAGCATTAC TGTTCTTATT

TGCTGCCACA CCTGAGCCAG CCTGCTCCTT CCCAGGAGTG GAGGAGGCCT GGGGGCAGGG AGAGGAGTGA CTGAGCTTCC CTCCCGTGTG TTCTCCGTCC CTGCCCCAGC AAGACAACTT AGATCTCCAG GAGAACTGCC ATCCAGCTTT GGTGCAATGG CTGAGTGCAC AAGTGAGTTG TTGCCCTGGG TTTCTTTAAT CTATTCAGCT AGAACTTTGA AGGACAATTT CTTGCATTAA TAAAGGTTAA GCCCTGAGGG GTCCCTGATA ACAACCTGGA GACCAGGATT TTATGGCTCC CCTCACTGAT GGACAAGGAG GTCTGTGCCA AAGAAGAATC CAATAAGCAC ATATTGAGCA CTTGCTGTAT ATGCAGTATT GAGCACTGTA GGCAAGAGGG AAGAAAGAGA AGGAGCCATC TCCATCTTGA AGGAACTCAA AGACTCAAGT GGGAACGACT GGGCACTGCC ACCACCAGAA AGCTGTTCGA TGAGACGGTC GAGCAGGGTG CTGTGGGTGA TATGGACAGC AGAAGGGGGA

GCCAGGTTCC AGCTCACCAA TACTATTGCA CACCACCTGT CCTGCCTC CTGCAGAAAA CAGCCTGAGC TCCACCTCGG CTTCTCCTTG CCCTGGCTGG TTGTCCTTAA CCCCTGTCTC CTTCTGGACC AGTTTTTGTC CTTCCCTTGT GACCCTGAGG GGTAACAGCC TCTTTTCCAC TTTCTTTCAG CGCCGACATG CTCAATGTCA CCTTGCAAGG GCCCACTCTT AACGGGACCT TTGCCCAGAG CAAATGCCCC CAAGTGGAGT GGCTGGGCTG GCTCAACACC ATCCAGCCCC CCTTCCTCTG GGTGCTGTTC GTGCTGGCCA CCCTAGAGAA CATCTTTGTC CTCAGCGTCT TCTGCCTGCA CAAGAGCAGC TGCACGGTGG CAGAGATCTA CCTGGGGAAC CTGGCCGCAG CAGACCTGAT CCTGGCCTGC GGGCTGCCCT TCTGGGCCAT CACCATCTCC AACAACTTCG ACTGGCTCTT TGGGGAGACG CTCTGCCGCG TGGTGAATGC CATTATCTCC ATGAACCTGT ACAGCAGCAT

CTGTTTCCTG ATGCTGGTGA GCATCGACCG CTACCTGGCC CTGGTGAAAA CCATGTCCAT GGGCCGGATG CGCGGCGTGC GCTGGGCCAA GCTCTACAGC TTGGTGATCT GGGGGTGTAC GCTGCTCCTG AGCTCACCCA TGCTGGTGTT CCGGACCATG AAGGAGTACA GCGATGAGGG CCACAACGTC ACCGCTTGTG TCATCAGCTA CCCATCCCTC ATCTGGGAAG TGTTCACCAA CATGCTCCTG AATGTCGTGG GCTTCCTGCT GCCCCTGAGT GTCATCACCT TCTGCACGAT GCAGATCATG CAGGTGCTGC GGAACAACGA GATGCAGAAG TTCAAGGAGA TCCAGACGGA GAGGAGGGCC ACGGTGCTAG TCCTGGTTGT GCTGCTGCTA TTCATCATCT GCTGGCTGCC CTTCCAGATC AGCACCTTCC TGGATACGCT GCATCGCCTC GGCATCCTCT CCAGCTGCCA GGACGAGCGC ATCATCGATG TAATCACACA GATCGCCTCC TTCATGGCCT ACAGCAACAG CTGCCTCAAC

CCACTGGTGT ACGTGATCGT GGGCAAGCGC TTCCGAAAGA AGTCTTGGGA GGTGTACCAG GGAGTGTGCC AGAAAGGGGG CTGCAGGTCA GAACCCATTC AGATGGAGAA CTCCATGGGC ACACTGCGGA CCTCCATCTC CGTGGAACGC CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG TCTCCGGTAA AACACCGGAG ACTAATTCCT GNCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC AGGAGTGGAG GAGGCCTGGG GGCAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC

TCCGTCCCTG CCCCAGCAAG ACAACTTAGA TCTCCAGGAG AACTGCCATC CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT CTTTAATCTA TTCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGGAGGT CTGTGCCAAA GAAGAATCCA ATAAGCACAT ATTGAGCACT TGCTGTATAT GCAGTATTGA GCACTGTAGG CAAGAGGGAA GAAAGAGAAG GAGCCATCTC CATCTTGAAG GAACTCAAAG ACTCAAGTGG GAACGACTGG CACTGCCACC ACCAGAAAGC TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC ACAACCACCT GTCCCTGCCT CAGTTCCCTC TTCTGTAACA TGAAGTCGTT GTGAGGGTTA

AAGGCAGTAA CAGGTATAAA GTACTTAGAA AAGCAAAGGG TGCTACGTAC ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT ACTATAAGGA AAAGACACTG AGGTCTAGA TGATCCTATC ACAACCTGAG AGTAGTTTTT ACTCCATTTA CAGGTGAGGT CATTGTGGTT CAAGGACGTT AAGTAACTTC CCCAGCTCAC ACGGCTTATA AGTAAGGCAG CCAGGATGTG AACCCAGTAG GACTATCTGG CTGCAAAGTC CCCACCCTCC CTCGCCATCT GTATCCTCCA ATCATCTTCA GTGCTTTGCT GATAGAAGGT ACGGAAATAC GATGCCACAG ACTGTCCAGG AAGACAGAAA CTAGGCAGAT GGGCTGGCCA TGGTCTCCAA GCCAGACTGG AATCTCCAGG TCTGGAATGA TATCATTTTT CTCTTTTAAT AAATTAACTC ACCCACCACA CGGCTTTGAG AGGCTCAAAG GTGACCAACT CCCTTGGGAG GGCCCCGGTT GATAAGGAAG GAATGTGAAT CCTCCCATCA

CGGAAGCTTC AAGGAGGTCA AGGGTCCAAC ACTTGAGATT GTTAGTGCTG TTGGTGGATA CTGCAGAATA TCCAGTGGAG CCTCAGATGA AGAACATGAG GCCCCGTTTA GATCCAAGGA TCAGAGGGGG CTCTGTAAGA CCCAGGGGAG TCAGGTGCAC TGGAGCGCGG GCTGCAGAAA ACAGCCTGAG CTCCACCTCG GCTTCTCCTT GCCCTGGCTG GTTGTCCTTA ACCCCTGTCT CCTTCTGGAC CAGTTTTTGT CCTTCCCTTG TGACCTGAGG GGTAACAGCC TCTTTTCCAC TTTCTTTCAG CGCCGACATG CTCAATGTCA CCTTGCAAGG GCCCACTCTT AACGGGACCT TTGCCCAGAG CAAATGCCCC CAAGTGGAGT GGCTGGGCTG GCTCAACACC ATCCAGCCCC CCTTCCTCTG GGTGCTGTTC GTGCTGGCCA CCCTAGAGAA CATCTTTGTC CTCAGCGTCT TCTGCCTGCA CAAGAGCAGC TGCACGGTGG CAGAGATCTA CCTGGGGAAC CTGGCCGCAG CAGACCTGAT

CCTGGCCTGC GGGCTGCCCT TCTGGGCCAT CACCATCTCC AACAACTTCG ACTGGCTCTT TGGGGAGACG CTCTGCCGCG TGGTGAATGC CATTATCTCC ATGAACCTGT ACAGCAGCAT CTGTTTCCTG ATGCTGGTGA GCATCGACCG CTACCTGGCC CTGGTGAAAA CCATGTCCAT GGGCCGGATG CGCGGCGTGC GCTGGGCCAA GCTCTACAGC TTGGTGATCT GGGGGTGTAC GCTGCTCCTG AGCTCACCCA TGCTGGTGTT CCGGACCATG AAGGAGTACA GCGATGAGGG CCACAACGTC ACCGCTTGTG TCATCAGCTA CCCATCCCTC ATCTGGGAAG TGTTCACCAA CATGCTCCTG AATGTCGTGG GCTTCCTGCT GCCCCTGAGT GTCATCACCT TCTGCACGAT GCAGATCATG CAGGTGCTGC GGAACAACGA GATGCAGAAG TTCAAGGAGA TCCAGACGGA GAGGAGGGCC ACGGTGCTAG TCCTGGTTGT GCTGCTGCTA TTCATCATCT GCTGGCTGCC CTTCCAGATC AGCACCTTCC TGGATACGCT GCATCGCCTC GGCATCCTCT CCAGCTGCCA GGACGAGCGC ATCATCGATG TAATCACACA GATCGCCTCC TTCATGGCCT ACAGCAACAG CTGCCTCAAC CCACTGGTGT ACGTGATCGT GGGCAAGCGC TTCCGAAAGA AGTCTTGGGA GGTGTACCAD GGAGTGTGCC AGAAAGGGGG CTGCAGGTCA GAACCCATTC AGATGGAGAA CTCCATGGGC ACACTGCGGA CCTCCATCTC CGTGGAACGC CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTGTTGA

TGTCTCCGGT AAAACACCGG AGACTAATTC CTGCCCTGCC CAATTTTCGA GGGAGCATGG CTGTGAGGAT GGGGTGAACT CACGCACAGC CAAGGACTCC AAAATCACAA CAGCATTACT GTTCTTATTT GCTGCCACAC CTGAGCCAGC CTGCTCCTTC CCAGGAGTGG AGGAGGCCTG GGGGAGGGAG AGGAGTGACT GAGCTTCCCT CCCGTGTGTT CTCCGTCCCT GCCCCAGCAA GACAACTTAG ATCTCCAGGA GAACTGCCAT CCACGTTTGG TGCAATGGCT GAGTGCACAA GTGAGTTGTT GCCCTGGGTT TCTTTAATCT ATCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTTGATAAC AACCTGGAGA CCAGGATTTT ATGGCTCCCC TCACTGATGG ACAAGGAGGT CTGTGCCAAA GAAGAATCAA TAAGCACATA TGAGCACTTC TGTATATCAG TATTGAGCAC TGTAGGCA ATGTTCTCTC CCTGGAAGAT ATCAATGTTT

CTGTCTGTTT GTGAGGACTC CGTGCCCACC ACGGCCTCTT TCAGCGCCGA CATGCTCAAT GTCACCTTGC AAGGGCCCAC TCTTAACGGG ACCTTTGCCC AGAGCAAATG CCCCCAAGTG GAGTGGCTGG GCTGGCTCAA CACCATCCAG CCCCCCTTCC TCTGGGTGCT GTTCGTGCTG GCCACCCTAG AGAACATCTT TGTCCTCAGC GTCTTCTGCC TGCACAAGAG CAGCTGCACG GTGGCAGAGA TCTACCTGGG GAACCTGGCC GCAGCAGACC TGATCCTGGC CTGCGGGCTG CCCTTCTGGG CCATCACCAT CTCCAACAAC TTCGACTGGC TCTTTGGGGA GACGCTCTGC CGCGTGGTGA ATGCCATTAT CTCCATGAAC CTGTACAGCA GCATCTGTTT CCTGATGCTG GTGAGCATCG ACCGCTACCT GGCCCTGGTG AAAACCATGT CCATGGGCCG GATGCGCGGC GTGCGCTGGG CCAAGCTCTA CAGCTTGGTG ATCTGGGGGT GTACGCTGCT CCTGAGCTCA CCCATGCTGG

TGTTCCGGAC CATGAAGGAG TACAGCGATG AGGGCCACAA CGTCACCGCT TGTGTCATCA GCTACCCATC CCTCATCTGG GAAGTGTTCA CCAACATGCT CCTGAATGTC GTGGGCTTCC TGCTGCCCCT GAGTGTCATC ACCTTCTGCA CGATGCAGAT CATGCAGGTG CTGCGGAACA ACGAGATGCA GAAGTTCAAG GAGATCCAGA CGGAGAGGAG GGCCACGGTG CTAGTCCTGG TTGTGCTGCT GCTATTCATC ATCTGCTGGC TGCCCTTCCA GATCAGCACC TTCCTGGATA CGCTGCATCG CCTCGGCATC CTCTCCAGCT GCCAGGACGA GCGCATCATC GATGTAATCA CACAGATCGC CTCCTTCATG GCCTACAGCA ACAGCTGCCT CAACCCACTG GTGTACGTGA TCGTGGGCAA GCGCTTCCGA AAGAAGTCTT GGGAGGTGTA CCAGGGAGTG TGCCAGAAAG GGGGCTGCAG GTCAGAACCC ATTCAGATGG AGAACTCCAT GGGCACACTG CGGACCTCCA

TCTCCGTGGA ACGCCAGATT CACAAACTGC AGGACTGGGC AGGGAGCAGA CAGTGAGCAA ACGCCAGCAG GGCTGCTGTG AATTTGTGTA AGGATTGAGG GACAGTTGCT T ATGTTCTCTC CCTGGAAGAT ATCAATGTTT CTGTCTGTTC GTGAGGACTC CGTGCCCACC ACGGCCTCTT TCAGCGCCGA CATGCTCAAT GTCACCTTGC AAGGGCCCAC TCTTAACGGG ACCTTTGCCC AGAGCAAATG CCCCCAAGTG GAGTGGCTGG GCTGGCTCAA CACCATCCAG CCCCCCTTCC TCTGGGTGCT GTTCGTGCTG GCCACCCTAG AGAACATCTT TGTCCTCAGC GTCTTCTGCC TGCACAAGAG CAGCTGCACG GTGGCAGAGA TCTACCTGGG GAACCTGGCC GCAGCAGACC TGATCCTGGC CTGCGGGCTG CCCTTCTGGG CCATCACCAT CTCCAACAAC TTCGACTGGC TCTTTGGGGA GACGCTCTGC CGCGTGGTGA ATGCCATTAT CTCCATGAAC CTGTACAGCA

GCATCTGTTT CCTGATGCTG GTGAGCATCG ACCGCTACCT GGCCCTGGTG AAAACCATGT CCATGGGCCG GATGCGCGGC GTGCGCTGGG CCAAGCTCTA CAGCTTGGTG ATCTGGGGGT GTACGCTGCT CCTGAGCTCA CCCATGCTGG TGTTCCGGAC CATGAAGGAG TACAGCGATG AGGGCCACAA CGTCACCGCT TGTGTCATCA GCTACCCATC CCTCATCTGG GAAGTGTTCA CCAACATGCT CCTGAATGTC GTGGGCTTCC TGCTGCCCCT GAGTGTCATC ACCTTCTGCA CGATGCAGAT CATGCAGGTG CTGCGGAACA ACGAGATGCA GAAGTTCAAG GAGATCCAGA CGGAGAGGAG GGCCACGGTG CTAGTCCTGG TTGTGCTGCT GCTATTCATC ATCTGCTGGC TGCCCTTCCA GATCAGCACC TTCCTGGATA CGCTGCATCG CCTCGGCATC CTCTCCAGCT GCCAGGACGA GCGCATCATC GATGTAATCA CACAGATCGC CTCCTTCATG GCCTACAGCA ACAGCTGCCT

CAACCCACTG GTGTACGTGA TCGTGGGCAA GCGCTTCCGA AAGAAGTCTT GGGAGGTGTA CCAGGGAGTG TGCCAGAAAG GGGGCTGCAG GTCAGAACCC ATTCAGATGG AGAACTCCAT GGGCACACTG CGGACCTCCA TCTCCGTGGA ACGCCAGATT CACAAACTGC AGGACTGGGC AGGGAGCAGA CAGTGAGCAA ACGCCAGCAG GGCTGCTGTG AATTTGTGTA AGGATTGAGG GACAGTTGCT T GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG GCTCCGAGGA GGGGTGGGGA CGGTGGGGAC ATCAGGCTGC CCCGCAGTAC CAGGGAGCGA CTGAAGTGCC CATGCCGCTT GCTCCGGAGA AGGTGGGTGC CGGGCAGGGG CTGCTCCAGC CGCCTCACCT CTGCTGGGAG GACAAACTGT CCCAGCACAG AGGGAGGGAG GGAGGGCAGG CAGCGGGGAG AAGTTTCCCT

GTGGTCGTGG GGAGTT GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG GCTCCGAGGA GGGGTGGGGA CGGTGGTGAC GGTGGGGACA TCAGGCTGCC CCGCAGTACC AGGGAGCGAC TGAAGTGCCC ATGCCGCTTG CTCCGGAGAA GGTGGGTGCC GGGCAGGGGC TGCTCCAGCC GCCTCACCTC TGCTGGGAGG ACAAACTGTC CCAGCACAGA GGGAGGGAGG GAGGGCAGGC AGCGGGGAGA AGTTTCCCTG TGGTCGTGGG GAGTT GAGCTCTTCA ATATTTTAGT GAAAGCTATA GATGAGGCTC CATAGGGGAT AAAGCACAGA CACACCTTTT CAGAGGGCTT GTGGACTCTG GGCAGCCTGT CCATAGACCT CTGTCCCCAA CTGGCAAGTC AGGAAACTCC AGATTAAGGA GCCCCAATGT GGTTGAACAG CCAGGTGCAC AGATGAGTCA ACCACACAGC CAGGCCAGGG AGGGCCTTCA CTCAAGAGCC TACAGCCAGT

TCACAGCCAA GCCAGGGCTA GCGCCAGGCC ACCCATAAAC TGATCTGAGA CTCTGTTTCC CTGTCTCCAT GATGATGGGA TCAGGCTTGA TTGCTGGTTT GTAGGCTTGT TATGAATCAA GTCACAGGGA AGAGGAGCTG ATGGGCTGGG GGGACGTCCT CTGGCCCTCC TGTCTCTTCC CCAGATCCAC TGGGCCCACT CTTATCTGTT CTCTTCTGAA GGAAGGGTTT TAAGGCTTCA AAAAAAAATG TTTTGAAAGT CCCTGCCCTT TCCAGCTCCT ACCGTCTCAG CCCTGGGAGT GTAAAGTGCT GCAGATAGTT AGTAAGTCTT TGAGCAAAAC TGAGAAAGCC AGCCTGAGCC TTGACATGGG AGAAACCTCC GCCATACATC TCCGAAGAAA CGGCCGCGTG TCTCAGGGGA GCGCAAACAC CCGTACCCAG GAAACAGGAC AGCTTCTGCC ACTGTCGCCC TTGGGAGCCG TACGTGGCAT GACAAAGAAA TCCCAGGACT CCGCCTGCCC ACCTGGCCAC CCTCTGTTTA

CACCTTCCGC GTAAACGCCC ACTGTTTACA TCCAAAACTC AGACACAAAA TAACCACCTC AAGAAGATAA ATAATGATAA GAAATAAATG TTACGCGAGG CAAATTTATT CACATGGGGC TTCCCAGGCC ACTTTGTGGT CAGCCGGGAG GGACGTTTTT GCCGTCCCAC GACTCCAACG GGCAGCCGGG CCTACGCAAA CATGGAAATC TTCCAAGAGC CTCCCTGGCC CCCAGGGCTC AGAGGGTGGC AGAGCGGAGA GCGAAGGTGG CCGCAGCCTT CCCGGCCCCA CAGCCAGCCT GGCTCCAGCT GGGCAGGAGT GCAGAGCTCA GCTGGAGGCG AGGGGGAAGT GCCCAGGAGG CTGATGACAT CACTACCCAG CCCTTCAAAG ATGAGCTGTT CCCGCCGCCA CTCCAGCTCT GGCTTCTGGG CTCCGAGGAG GGGTGGGGAC GGTGGTGACG GTGGGGACAT CAGGCTGCCC CGCAGTACCA GGGAGCGACT GAAGTGCCCA TGCCGCTTGC TCCGGAGAAG

GTGGGTGCCG GGCAGGGGCT GCTCCAGCCG CCTCACCTCT GCTGGGAGGA CAAACTGTCC CAGCACAGAG GGAGGGAGGG AGGGCAGGCA GCGGGGAGAA GTTTCCCTGT GGTCGTGGGG AGTTGGGAAA AGTTCCCTTC CTTCCGGAGG GAGG CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG TCTCCGGTAA AACACCGGAG ACTAATTCCT GCCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC AGGAGTGGAG GAGGCCTGGG GGGAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC

TCCGTCCCTG CCCCAGCAAG ACAACTTAGA TCTCCAGGAG AACTGCCATC CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT CTTTAATCTA TTCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGAGGTC TGTGCCAAAG AAGAATCCAA TAAGCACATA TTGAGCACTT GCTGTATATG CAGTATTGAG CACTGTAGGC AAGACCCAAG AAAGAGAAGG AGCCATCTCC ATCTTGAAGG AACTCAAAGA CTCAAGTGGG AACGACTGGG CACTGCCACC ACCAGAAAGC TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC ACAACCACCT GTCCCTGCCT CAGTTCCCTT TTATGTAACA TGAAGTCGTT GTGAGGGTTA

AAGGCAGTAA CAGGTATAAA GTACTTAGAA AAGCAAAGGG TGCTACGTAC ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT ACTATAAGGA AAAGACACTG AGGTCTAGAA ATAGCTCCGT GGAGCAGAAT CAGTATTGGG AGCCGGTGGC GGTGTGAAGC ACCAGTGTCT GGCACACAGT AGGTGCTCAT TGGCTCCCTT CCACCTGTCA TTCCCACCAC CCTGAGGCCC CAACCGCCAC ACACACAGGA GCATTTGGAG AGAAGGCCAT GTCTTCAAAG TCTGATTTGT GATGAGGCAG AGGAAGATAT TTCTAATCGG TCTTGCCCAG AGGATCACAG TGCTGAGACC CCCCACCACC AGCCGGTACC TGGGAAGGGG GAGAGTGCAG GCCTGCTCAG GGACTGTTCC TGTCTCAGCA ACCAAGGGAT TGTTCCTGTC AATCAATGGT TTATTGGAAG GTGGCCCAGT ATGAGCCCTA GAAGAGTGTG AAAAGGAATG GCAATGGTGT TCACCATCGG CAGTGCCAGG GCAGCACTCA

TTCACTTGAT AAATGAATAT TTATTAGCTG GTTGGAGAGC TAGAACCTGG AGAGCTAGAA CCTGGAGAAC TAGAACCTGG AGGGCTAGAA CCTGGAGAGG CTAGAACCAA GAAGGGCTAG AACCTGGAGG GGCTAGAACC TAGAGAAGCT AAAACCTGAG CTAGAAGCTG GAGGACTAGA ACCTGGAGGG CTGGAATCTG AAGGGCTAGA ACCTGGAGGG CTGGAATCTG GAGAGCTAGA ACCTGGAGGG CTAGAACCTG GAGGGCTAGA ACCTAGAAGG GCTAGAACCT GGAGGGCTGG AATCTGGAGA GCTAGAACCT GGAGGGCTAG AACCTGGAGG GCTAGAACCT AGAAGGGCTA GAACCTGGAG GGCTAGAACC TGGCAGGTTA GAACCTAGAA GGGCTAGAAC CTGGAGAGCC AGAACCTGGA GGGCTAGAAC CTGGAAGGGC TAGAACCTGT AGAGCTAGAA CATGGAGAGC TAGAACCCGG CAGGCTAGAA CCTGGCAAGC

TAGAACCTGG AGGGAATGAA CCTGGAGGGC TAGAACCTGG AGAATGAGAA AAATTTACAT GGCAAAGAGC CCATAAATCC TGACCAATCC AACTCTGAAT TTTAAAGCAA AAGCGTGAAA AAAAAGATTC CCTCCTTACC CCCAACCCAC TCTTTTTTCC CACCACCCAC TCTCCTCTGC CTCAGTAAGT ATCTGGAGGA AGAAAACAGG TGAAAGAAGA AGTAAAAACC ATTTAGTATT AGTATTAGAA TGAAGTCAAA CTGTGCCACA CATGGTGAAT GAAAAAAAAA AAAAAGAGGC TGTGTTTTGT CACACAGGGC AGTCATTCAG CACCAGAGCA CGTGATGGTC TGAGACTCTC TTAGGAGCAG AGCTCTGCCG CAATGGCCAT GTGGGGATCC ACACCTGGTC TGAGGGGCAA CTGAGTCTGC GGGAGAAGAG CGGCCCTATG CATGGTGTAG ATGCCCTGAT AAAGAACATC TGTCCTGTGA AAGACTCAAT GAGCTGTTAT GTTGTAAACA GGAAGCATTT CACATCCAAA

CGAGAAAATC ATGTAAACAT GTGTCTTTTC TGTAGAGCAT AATAAATGGA TGAGGTTTTT GCAAAAAAAA AAAAAAAAA AAATGATAGA CCGTCAATAA TTTGTTAAAT GCTTTTTAAA ATGAATGCTT TAAGCCGGGT GCAGTGCCTC ACATCTGTAA TCCCAGCACT TTGGAGCCGA GCGGGTGGAT TGTGTGAGGT CAGGAGTTCG AGACCAACCT GGCCAACATG GCAAAACCTC ACTCTCTACC AAAAATACAA AAATTAGCCA GGCATGGTGG CAGGCACCTG TGATCCCAGC TACTCAGGAG GCTGAGACAG GAGAATCGCT TGAACCCGGG AGGCAAGGTT GCAGTGAGCC AAGATTACGC CATTGTACTC CAGCCTGGGT GACAGAGAGA GACTCCGTCT CAAAAAAAAA AAAAAAAAAA AAAAAATTAC GCTTCAAACA CATGATCTCT CACCACTGTT GAATTTTCTT TCTATGAGCC CAGGAGGGCC TCTCAGAGAG GAAAGCTCCT AGGTCTTCCT TTCCCTCTGC

AAACTCCCTG CCTTGAAGGT TCAGAAGGAC TGTGCGTGCT CGTTGCATCC TTTGCAAGTG TCCAAACCCT GATCCCAGCT GTGCTTAGGG GTTCCTGCAA ACCTTTTCCA GGTGTTAATT ACCTCCCACT TCATTTCCTG TTTACCAACT CAGCTTTTTG TTTTAGTGTG TTTGAATTCC CTGAACTGAC CGTTGTCTGA TCTCCACCTC CCAACTGAAT TAGGGGAGCT GGGCTTCTGG AAACCCAGGT GCCGGGTGTT GCAGAGTGGC TGAAAGCTGG GATGTGGCAG ATCCGTGGCT ACATTCATGC ACACACACAC ACCCACATAC CCACACATGC ACACACACAC ACACACCCGC ACTCACACAC TTGGACATGC ATAGACCACA GCTTTCCACA CCCTTCCTAG ACAGGGGTCA CTTGGTATCC TGGAGAGAGT GTGAAGTCCT GGAATGGAAA GAGGGGGGAT TAAGCCCCAC CTCTAGCCAT GGGACTGAGA CAAGTCACCA CCAACCCATC TGCGCCTTGT TTACCTCCTC TGTGAGGCAA

GCACAGAGCC CATGCCTGCC CCCCTGGATG GGAGTGATGT GAAACTTGAA GGGCGGTCAG AGCAAGGGTC GGGAATGGAA GGCCCTTGGG AAAAAAGGCC CTTTCAACTA GGGGCACAGA GGAGGCCCTG GGCTGAGAAC TTGACAGCAC CTTGTAATTG GTAAGCCAAG CCCGAAGGGA CTGGAAATAC TCAGATGTGT CTGTCTCCCT TATTAGGTTC AAAGTCCCTC AAGACCCTGT CTCCATCACA GTGCTCCAGT CCAGACCCCT CCTCTGAGCT CCAGACCCTG CTGGACCCAA CCAGCCCTAT GGGGTCGCAT CCCCACCTGC CTGGAATTCT CCAAAGAACC TCCCCTTTAA CAGTTCCAGC CTTTAACAGT TCCAGTCTAA ACACATGACC TTTCTCCTCT AAATCAGCCC CCCATCTCTG CCTTTGCAGG AGATGGAAGC CATGACACCT GCCTCGCCCC TGTCCTCACC CCATCCATGT CCAATCAAGC ACTAGGCATG TCAGGTTTAC CCTCTAAACT CCTCTGGAAT

CCAGTCTCTC AGTCTCCATC ATCCCAGGTC GAAGCTAATG GGCTAACTGG TCCTTGCTTC CACTCTACCC CCACTGCAGT CCTGACTTCC TGAGCAGCAG CCAGGGCCTA ATCGATATTC ACACCAAGCG CCAACCTGAC TGAGATATCC TCCTGCACCA TCATCCCTCC ACCCTGTTTA GTTCTGCTCA CCCTCAGTGT TCTCATCAAT AATCCACTCC CCTCACAGGC GCGTTTGGGA CCCCATGTTC TATGCTCTCA CAGGACCTTT TGCTTGATTT TTCACTGTAC TTAGGTCAGT TTGCAGTTAT TAAGTGACTG AGCAATGTCT GGCTTCTCCA GTAGACTGTC AGCTCCTAGC CATTGTATAC CTAGCACCGC TGTGTGGGAG CACGTGACAA ACGTCCAGTG AGTCAGGGAC TCAGCAGTCT CCATTTCTCC GCCCTGCTGG AGAATGCGTG TATTTGGCAA TCCCCAGCCC CTGTGCCATC TAACCATCTT TTCTTCTCTG TTCAGCCCAG GTGTGGCCTC ACTCACATCC CACTCTGAGT

CCAAATGTTC TCTCCCTGGA AGATATCAAT GTTTCTGTCT GTTCGTGAGG ACTCCGTGCC CACCACGGCC TCTTTCAGGT GAGTCAAAGG GATTCCTCAG TTCACTAGTT AGGGGAGGTG GGCAGACACC CTGGAGAACT CCCTGGAAAG CTCAACTCTC ATGCCCCGGA CAACAGTTGA AGGAACCATG GTGATGTTAA GCCCAAAGAC AAAACCTCTC AGGTGTCCAA GTCCCTGTTG GAATCTTGGG AGCAGAGGGA ATGTTCTGTG GTCTAGAGGA AGAGGGGCTC AGGGAGGAGA AGGGCACATT CCTGGTTGTT ATATGTTTCT ATCTATCCCA GATGAACTTG GAAGTGAAGG GAAGAGAGTT AAACATTAAA GTAAATACCC AGTGGATCAG ACAGCAATGT GCCAGATTGC CTTGGAAACA AAATATCTCC AACACATGGC TGACATTTGG TGGGAGATCA GAACACCCTA AAGAGAGAAT TTAAGGGGAG GGGGAGGAGG ACCTGAGCCA GAGTAGAAGC AGAGGATAGG GAGATCTGTT CTTGGGGACA GCATTTGCAA GAAACAAGGC TGAGGGGTCC ACTCCAACCT CTCCACCCTG CTGCAGGTGC TGCCTATGAT GAAGATGAGC AGATGGCCAT CTCAGCTGGG GCCACAGTGC ACTGGACCTA TAGTTTCCAA TTCCGCACTC AGCAGGCATC TTTCTGATGA TCCGATGGCT TCTCAGAGCC AGGGATGGGC CAGGATCCAT CCCCTTGGCT ACTGTCTTGC TGAGAAATTT ATAAGCAGCA TCTGGTGCTA TACTTTGGTC TCTAGTGAGT TAGCTCATGA AAGATGATAG ACTCTCCAAG CCAGGGGTAT GCAGGAAATG GGTTTTCTGT AGCTACAGAA ATGGGGTTGA GGGTTGGACC AAGGGACTAC CCAGGGGAAG TCTTACCTTC AGAGGACTCT GGAAAGGAGG CTGCAAGTTT

TCATGGGTCA AGAATTCAGA GCCCAGTAGA GACAGCTTAT CTCTGTTCCA AGATGTCTGG GGCCTTGGTT GGAAGATTCA AAGGCTAGGA AACCAGGAGC CACCAAAAGC GTAACTGGGG CCAGAGGATC CACTTTCAAG GTGGCAAGTT GGTTCCCCCC ATGTGGCTGC TTGAGTATCC TCACATGGCG GCTCACATCC TTCCAAGTAA GCAATGCAAA AGGCCAAGAA AGATGCTGCA AAGATGTTAT GACCTAGCCT CAGAAATCAC ACACCATCCC TGCCACCATT AGTAAGAAGT CCAGCCCACG TCCAGGAGAA GAGGAAGCAG ATTCCTCCTT TTGAAATGAA GAATATCAAG TAATTCGGGG GGCATATGAA AGCCACCACA CACCACAGGG ATCTTTTTAG AGCATACTTC TTATACCATC ACTGTAGTTC CTTAAGACTC AGGGGCAAAG CCTCACTTCC TTAGCACCCA GTGAAGACCA CGCTTACTCC CTCACTCAAC CTCTTGCTAC TTCCCACCTC TCCTGTCCAA CATCTAGTGT

CACTTTCCAG AACATACCAA CAGCTTCCCC AGTTCTGTGC CTCTGCTCAG GCTGTTCCCC CTGCCTGGTC CACTTGTCCT CCTTCTTGTC CGGTCAAAAT GCTTCTTATC CTTCAAGACC CAGCTCTAGA GTCACCTCCA ACCCCTTACC CACCAGCCCC CTCTCCAAGT CTGTGTCCCA CAACCCCCCT GCTCCCTCCA GGGCACCCTC CACCCTCTGG GCCACAGTTG TCAGGAGTCA GGCAGGGCAG GGGCCGGGTG GTGTCTTCTT TGTGTTCTTG CACTCAGGGC AGAGCTCAGC ACAGAGCAGA CGCTCAAAAA ACATTTAAAG GATAGAAGCA TTGATTTGTG GGTCCCCCAG TCTGGCTCCA GGATGCCAGC CAGCTGCTCC TAGAAGCAAA CGGACTTTTC CTGGGAAATC CCAGAGGTGA TGATCAGTAA TCTCTCCCGT GACTCGTAGT TCAGCTCTTC CTCCATGAGC CTGACTATCA GTGGACCTTC CAGAAAGAGC CCCTTTTCCT TCTCTCACCC ACAGCACAGG GCACTGGGAA

AATGCCCAAT GAGTCCTGCC TCTGGGTTGT GCTTTGGACT TTTCAGTGTG TCTCGCATCC ACTCTTCAAC TTGAATGTTG CAACAGCCAT GAAAAAAGAA ATGCAAAGCG ATTCAGGATG AGAGCAATAC CCTACTCCAA AGAAGGCAAC ATAGAAGCTC AGAGAGATCA AGCAATTTGC CCAAGACCAC ACAGCTAGGA GTGGAACTCA TGGCTGTCCA AGCCCCATGC CTCTGCTGAA GGTAGAGATG AATTACAGCA ACAAGTCTAG AAAGGTGCCT GCCCTATGGT CTGTGAGTCT TGCCTAAGAA TGAAAGAGGA GCCAGTGGGT TAAAGATGAG GTCACCAACA ACGGTGGTGT TGGAGTTTAC CACTGATAAT AAGGGTGCAA AATGTAAATT ACTAATGTTT ATTGAGCCTA GTGCAGTGCG TGGGGCATTT TGCACATTGT CTCTGATCCC TATGACAACC CTGAGAGGTA GTGGTTTTAA CTGCCATGTT ACAGGTGAGG TCATTGTGGT TCAAGGACGT TAAGTAACTT CCCCAGCGTG

ACACGGCTTA TAAGTAAGGC AGCCAGGATG TGAACCCAGT AGGACTATCT GGCTGCAAAG TCCCCACCCC CCTCGCCATC TGTATCCTCC AATCACTTCA GTGCTTTGCT GCATAGAAGG TAACGGAAAT CACGATGCCA CAGACTGTCC AGGAAGACAG AAACTAGGCA GATGGGCTGG CCATGGTCTC CAAGCCAGAC TGGAATCTCC AGGTCTGGAA TGATATCATT TTTCTCTTTT AATAAATTAA CTCACCCACC ACACGGCTTT GAGAGGCTCA AAGTTGACCA ACTCCCTTGG GAGGGCCCCG GTTGATAAGG AAGGAACGTG AATCCTCCCA TCACGGAAGC TTCAAGGAGG TCAAGGGTCC AACACTTGAG ATTGTTAGTG CTGTTGGTGG ATACTGGCCA AGGAAATATC CCAGTGGAGC CTCGAGATGA AGAACATGAG GCCCCCGTTT AGAACCAAGG ATCAGAGGGG GCTCTGTAAG ACCCAGGGGA GTCAGGTGCA CTGGAGCGCG GGCATGCAGA

AAACAGCCTG AGCTCCACCT CGGCTTCTCC TTGTCCTGGC TGGTTGTCCT TAACCCCTGT CTCCTTCTGG ACCAGTTTTT GTCCTTCCCT TGTGACCGCT GAGGGGTAAC AGCCTCTTTC CACTTTCTTT CAGCGCCGAC ATGCTCAATG TCACCTTGCA AGGGCCCACT CTTAACGGGA CCTTTGCCCA GAGCAAATGC CCCCAAGTGG AGTGGCTGGG CTGGCTCAAC ACCATCCAGC CCCCCTTCCT CTGGGTGCTG TTCGTGCTGG CCACCCTAGA GAACATCTTT GTCCTCAGCG TCTTCTGCCT GCACAAGAGC AGCTGCACGG TGGCAGAGAT CTACCTGGGG AACCTGGCCG CAGCAGACCT GATCCTGGCC TGCGGGCTGC CCTTCTGGGC CATCACCATC TCCAACAACT TCGACTGGCT CTTTGGGGAG ACGCTCTGCC GCGTGGTGAA TGCCATTATC TCCATGAACC TGTACAGCAG CATCTGTTTC CTGATGCTGG TGAGCATCGA CCGCTACCTG GCCCTGGTGA AAACCATGTC

CATGGGCCGG ATGCGCGGCG TGCGCTGGGC CAAGCTCTAC AGCTTGGTGA TCTGGGGGTG TACGCTGCTC CTGAGCTCAC CCATGCTGGT GTTCCGGACC ATGAAGGAGT ACAGCGATGA GGGCCACAAC GTCACCGCTT GTGTCATCAG CTACCCATCC CTCATCTGGG AAGTGTTCAC CAACATGCTC CTGAATGTCG TGGGCTTCCT GCTGCCCCTG AGTGTCATCA CCTTCTGCAC GATGCAGATC ATGCAGGTGC TGCGGAACAA CGAGATGCAG AAGTTCAAGG AGATCCAGAC GGAGAGGAGG GCCACGGTGC TAGTCCTGGT TGTGCTGCTG CTATTCATCA TCTGCTGGCT GCCCTTCCAG ATCAGCACCT TCCTGGATAC GCTGCATCGC CTCGGCATCC TCTCCAGCTG CCAGGACGAG CGCATCATCG ATGTAATCAC ACAGATCGCC TCCTTCATGG CCTACAGCAA CAGCTGCCTC AACCCACTGG TGTACGTGAT CGTGGGCAAG CGCTTCCGAA AGAAGTCTTG

GGAGGTGTAC CAGGGAGTGT GCCAGAAAGG GGGCTGCAGG TCAGAACCCA TTCAGATGGA GAACTCCATG GGCACACTGC GGACCTCCAT CTCCGTGGAA CGCCAGATTC ACAAACTGCA GGACTGGGCA GGGAGCAGAC AGTGAGCAAA CGCCAGCAGG GCTGCTGTGA ATTTGTGTAA GGATTGAGGG ACAGTTGCTT TTCAGCATGG GCCCAGGAAT GCCAAGGAGA CATCTATGCA CGACCTTGGG AAATGAGTTG ATGTCTCCGG TAAAACACCG GAGACTAATT CCTGCCCTGC CCAATTTTGC AGGGAGCATG GCTGTGAGGA TGGGGTGAAC TCACGCACAG CCAAGGACTC CAAAATCACA ACAGCATTAC TGTTCTTATT TGCTGCCACA CCTGAGCCAG CCTGCTCCTT CCCAGGAGTG GAGGAGGCCT GGGGGCAGGG AGAGGAGTGA CTGAGCTTCC CTCCCGTGTG TTCTCCGTCC CTGCCCCAGC AAGACAACTT AGATCTCCAG GAGAACTGCC

ATCCAGCTTT GGTGCAATGG CTGAGTGCAC AAGTGAGTTG TTGCCCTGGG TTTCTTTAAT CTATTCAGCT AGAACTTTGA AGGACAATTT CTTGCATTAA TAAAGGTTAA GCCCTGAGGG GTCCCTGATA ACAACCTGGA GACCAGGATT TTATGGCTCC CCTCACTGAT GGACAAGGAG GTCTGTGCCA AAGAAGAATC CAATAAGCAC ATATTGAGCA CTTGCTGTAT ATGCAGTATT GAGCACTGTA GGCAAGAGGG AAGAAAGAGA AGGAGCCATC TCCATCTTGA AGGAACTCAA AGACTCAAGT GGGAACGACT GGGCACTGCC ACCACCAGAA AGCTGTTCGA TGAGACGGTC GAGCAGGGTG CTGTGGGTGA TATGGACAGC AGAAGGGGGA GCCAGGTTCC AGCTCACCAA TACTATTGCA CACCACCTGT CCTGCCTC CTGCAGAAAA CAGCCTGAGC TCCACCTCGG CTTCTCCTTG CCCTGGCTGG TTGTCCTTAA CCCCTGTCTC CTTCTGGACC

AGTTTTTGTC CTTCCCTTGT GACCCTGAGG GGTAACAGCC TCTTTTCCAC TTTCTTTCAG CGCCGACATG CTCAATGTCA CCTTGCAAGG GCCCACTCTT AACGGGACCT TTGCCCAGAG CAAATGCCCC CAAGTGGAGT GGCTGGGCTG GCTCAACACC ATCCAGCCCC CCTTCCTCTG GGTGCTGTTC GTGCTGGCCA CCCTAGAGAA CATCTTTGTC CTCAGCGTCT TCTGCCTGCA CAAGAGCAGC TGCACGGTGG CAGAGATCTA CCTGGGGAAC CTGGCCGCAG CAGACCTGAT CCTGGCCTGC GGGCTGCCCT TCTGGGCCAT CACCATCTCC AACAACTTCG ACTGGCTCTT TGGGGAGACG CTCTGCCGCG TGGTGAATGC CATTATCTCC ATGAACCTGT ACAGCAGCAT CTGTTTCCTG ATGCTGGTGA GCATCGACCG CTACCTGGCC CTGGTGAAAA CCATGTCCAT GGGCCGGATG CGCGGCGTGC GCTGGGCCAA GCTCTACAGC TTGGTGATCT GGGGGTGTAC GCTGCTCCTG

AGCTCACCCA TGCTGGTGTT CCGGACCATG AAGGAGTACA GCGATGAGGG CCACAACGTC ACCGCTTGTG TCATCAGCTA CCCATCCCTC ATCTGGGAAG TGTTCACCAA CATGCTCCTG AATGTCGTGG GCTTCCTGCT GCCCCTGAGT GTCATCACCT TCTGCACGAT GCAGATCATG CAGGTGCTGC GGAACAACGA GATGCAGAAG TTCAAGGAGA TCCAGACGGA GAGGAGGGCC ACGGTGCTAG TCCTGGTTGT GCTGCTGCTA TTCATCATCT GCTGGCTGCC CTTCCAGATC AGCACCTTCC TGGATACGCT GCATCGCCTC GGCATCCTCT CCAGCTGCCA GGACGAGCGC ATCATCGATG TAATCACACA GATCGCCTCC TTCATGGCCT ACAGCAACAG CTGCCTCAAC CCACTGGTGT ACGTGATCGT GGGCAAGCGC TTCCGAAAGA AGTCTTGGGA GGTGTACCAG GGAGTGTGCC AGAAAGGGGG CTGCAGGTCA GAACCCATTC AGATGGAGAA CTCCATGGGC

ACACTGCGGA CCTCCATCTC CGTGGAACGC CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG TCTCCGGTAA AACACCGGAG ACTAATTCCT GNCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC AGGAGTGGAG GAGGCCTGGG GGCAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC TCCGTCCCTG CCCCAGCAAG ACAACTTAGA TCTCCAGGAG AACTGCCATC CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT CTTTAATCTA TTCAGCTAGA ACTTTGAAGG

ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGGAGGT CTGTGCCAAA GAAGAATCCA ATAAGCACAT ATTGAGCACT TGCTGTATAT GCAGTATTGA GCACTGTAGG CAAGAGGGAA GAAAGAGAAG GAGCCATCTC CATCTTGAAG GAACTCAAAG ACTCAAGTGG GAACGACTGG CACTGCCACC ACCAGAAAGC TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC ACAACCACCT GTCCCTGCCT CAGTTCCCTC TTCTGTAACA TGAAGTCGTT GTGAGGGTTA AAGGCAGTAA CAGGTATAAA GTACTTAGAA AAGCAAAGGG TGCTACGTAC ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT ACTATAAGGA AAAGACACTG AGGTCTAGA TGATCCTATC

ACAACCTGAG AGTAGTTTTT ACTCCATTTA CAGGTGAGGT CATTGTGGTT CAAGGACGTT AAGTAACTTC CCCAGCTCAC ACGGCTTATA AGTAAGGCAG CCAGGATGTG AACCCAGTAG GACTATCTGG CTGCAAAGTC CCCACCCTCC CTCGCCATCT GTATCCTCCA ATCATCTTCA GTGCTTTGCT GATAGAAGGT ACGGAAATAC GATGCCACAG ACTGTCCAGG AAGACAGAAA CTAGGCAGAT GGGCTGGCCA TGGTCTCCAA GCCAGACTGG AATCTCCAGG TCTGGAATGA TATCATTTTT CTCTTTTAAT AAATTAACTC ACCCACCACA CGGCTTTGAG AGGCTCAAAG GTGACCAACT CCCTTGGGAG GGCCCCGGTT GATAAGGAAG GAATGTGAAT CCTCCCATCA CGGAAGCTTC AAGGAGGTCA AGGGTCCAAC ACTTGAGATT GTTAGTGCTG TTGGTGGATA CTGCAGAATA TCCAGTGGAG CCTCAGATGA AGAACATGAG GCCCCGTTTA GATCCAAGGA TCAGAGGGGG

CTCTGTAAGA CCCAGGGGAG TCAGGTGCAC TGGAGCGCGG GCTGCAGAAA ACAGCCTGAG CTCCACCTCG GCTTCTCCTT GCCCTGGCTG GTTGTCCTTA ACCCCTGTCT CCTTCTGGAC CAGTTTTTGT CCTTCCCTTG TGACCTGAGG GGTAACAGCC TCTTTTCCAC TTTCTTTCAG CGCCGACATG CTCAATGTCA CCTTGCAAGG GCCCACTCTT AACGGGACCT TTGCCCAGAG CAAATGCCCC CAAGTGGAGT GGCTGGGCTG GCTCAACACC ATCCAGCCCC CCTTCCTCTG GGTGCTGTTC GTGCTGGCCA CCCTAGAGAA CATCTTTGTC CTCAGCGTCT TCTGCCTGCA CAAGAGCAGC TGCACGGTGG CAGAGATCTA CCTGGGGAAC CTGGCCGCAG CAGACCTGAT CCTGGCCTGC GGGCTGCCCT TCTGGGCCAT CACCATCTCC AACAACTTCG ACTGGCTCTT TGGGGAGACG CTCTGCCGCG TGGTGAATGC CATTATCTCC ATGAACCTGT ACAGCAGCAT CTGTTTCCTG

ATGCTGGTGA GCATCGACCG CTACCTGGCC CTGGTGAAAA CCATGTCCAT GGGCCGGATG CGCGGCGTGC GCTGGGCCAA GCTCTACAGC TTGGTGATCT GGGGGTGTAC GCTGCTCCTG AGCTCACCCA TGCTGGTGTT CCGGACCATG AAGGAGTACA GCGATGAGGG CCACAACGTC ACCGCTTGTG TCATCAGCTA CCCATCCCTC ATCTGGGAAG TGTTCACCAA CATGCTCCTG AATGTCGTGG GCTTCCTGCT GCCCCTGAGT GTCATCACCT TCTGCACGAT GCAGATCATG CAGGTGCTGC GGAACAACGA GATGCAGAAG TTCAAGGAGA TCCAGACGGA GAGGAGGGCC ACGGTGCTAG TCCTGGTTGT GCTGCTGCTA TTCATCATCT GCTGGCTGCC CTTCCAGATC AGCACCTTCC TGGATACGCT GCATCGCCTC GGCATCCTCT CCAGCTGCCA GGACGAGCGC ATCATCGATG TAATCACACA GATCGCCTCC TTCATGGCCT ACAGCAACAG CTGCCTCAAC CCACTGGTGT

ACGTGATCGT GGGCAAGCGC TTCCGAAAGA AGTCTTGGGA GGTGTACCAG GGAGTGTGCC AGAAAGGGGG CTGCAGGTCA GAACCCATTC AGATGGAGAA CTCCATGGGC ACACTGCGGA CCTCCATCTC CGTGGAACGC CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTGTTGA TGTCTCCGGT AAAACACCGG AGACTAATTC CTGCCCTGCC CAATTTTCGA GGGAGCATGG CTGTGAGGAT GGGGTGAACT CACGCACAGC CAAGGACTCC AAAATCACAA CAGCATTACT GTTCTTATTT GCTGCC ACAC CTGAGCCAGC CTGCTCCTTC CCAGGAGTGG AGGAGGCCTG GGGGAGGGAG AGGAGTGACT GAGCTTCCCT CCCGTGTGTT CTCCGTCCCT GCCCCAGCAA

GACAACTTAG ATCTCCAGGA GAACTGCCAT CCACGTTTGG TGCAATGGCT GAGTGCACAA GTGAGTTGTT GCCCTGGGTT TCTTTAATCT ATCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTTGATAAC AACCTGGAGA CCAGGATTTT ATGGCTCCCC TCACTGATGG ACAAGGAGGT CTGTGCCAAA GAAGAATCAA TAAGCACATA TGAGCACTTC TGTATATCAG TATTGAGCAC TGTAGGCA ATGTTCTCTC CCTGGAAGAT ATCAATGTTT CTGTCTGTTT GTGAGGACTC CGTGCCCACC ACGGCCTCTT TCAGCGCCGA CATGCTCAAT GTCACCTTGC AAGGGCCCAC TCTTAACGGG ACCTTTGCCC AGAGCAAATG CCCCCAAGTG GAGTGGCTGG GCTGGCTCAA CACCATCCAG CCCCCCTTCC TCTGGGTGCT GTTCGTGCTG GCCACCCTAG AGAACATCTT TGTCCTCAGC GTCTTCTGCC TGCACAAGAG CAGCTGCACG

GTGGCAGAGA TCTACCTGGG GAACCTGGCC GCAGCAGACC TGATCCTGGC CTGCGGGCTG CCCTTCTGGG CCATCACCAT CTCCAACAAC TTCGACTGGC TCTTTGGGGA GACGCTCTGC CGCGTGGTGA ATGCCATTAT CTCCATGAAC CTGTACAGCA GCATCTGTTT CCTGATGCTG GTGAGCATCG ACCGCTACCT GGCCCTGGTG AAAACCATGT CCATGGGCCG GATGCGCGGC GTGCGCTGGG CCAAGCTCTA CAGCTTGGTG ATCTGGGGGT GTACGCTGCT CCTGAGCTCA CCCATGCTGG TGTTCCGGAC CATGAAGGAG TACAGCGATG AGGGCCACAA CGTCACCGCT TGTGTCATCA GCTACCCATC CCTCATCTGG GAAGTGTTCA CCAACATGCT CCTGAATGTC GTGGGCTTCC TGCTGCCCCT GAGTGTCATC ACCTTCTGCA CGATGCAGAT CATGCAGGTG CTGCGGAACA ACGAGATGCA GAAGTTCAAG GAGATCCAGA CGGAGAGGAG GGCCACGGTG

CTAGTCCTGG TTGTGCTGCT GCTATTCATC ATCTGCTGGC TGCCCTTCCA GATCAGCACC TTCCTGGATA CGCTGCATCG CCTCGGCATC CTCTCCAGCT GCCAGGACGA GCGCATCATC GATGTAATCA CACAGATCGC CTCCTTCATG GCCTACAGCA ACAGCTGCCT CAACCCACTG GTGTACGTGA TCGTGGGCAA GCGCTTCCGA AAGAAGTCTT GGGAGGTGTA CCAGGGAGTG TGCCAGAAAG GGGGCTGCAG GTCAGAACCC ATTCAGATGG AGAACTCCAT GGGCACACTG CGGACCTCCA TCTCCGTGGA ACGCCAGATT CACAAACTGC AGGACTGGGC AGGGAGCAGA CAGTGAGCAA ACGCCAGCAG GGCTGCTGTG AATTTGTGTA AGGATTGAGG GACAGTTGCT T ATGTTCTCTC CCTGGAAGAT ATCAATGTTT CTGTCTGTTC GTGAGGACTC CGTGCCCACC ACGGCCTCTT TCAGCGCCGA CATGCTCAAT GTCACCTTGC AAGGGCCCAC TCTTAACGGG ACCTTTGCCC AGAGCAAATG CCCCCAAGTG GAGTGGCTGG GCTGGCTCAA CACCATCCAG CCCCCCTTCC TCTGGGTGCT GTTCGTGCTG GCCACCCTAG AGAACATCTT TGTCCTCAGC GTCTTCTGCC TGCACAAGAG CAGCTGCACG GTGGCAGAGA TCTACCTGGG GAACCTGGCC GCAGCAGACC TGATCCTGGC CTGCGGGCTG CCCTTCTGGG CCATCACCAT CTCCAACAAC TTCGACTGGC TCTTTGGGGA GACGCTCTGC CGCGTGGTGA ATGCCATTAT CTCCATGAAC CTGTACAGCA GCATCTGTTT CCTGATGCTG GTGAGCATCG ACCGCTACCT GGCCCTGGTG AAAACCATGT CCATGGGCCG GATGCGCGGC GTGCGCTGGG CCAAGCTCTA CAGCTTGGTG ATCTGGGGGT

GTACGCTGCT CCTGAGCTCA CCCATGCTGG TGTTCCGGAC CATGAAGGAG TACAGCGATG AGGGCCACAA CGTCACCGCT TGTGTCATCA GCTACCCATC CCTCATCTGG GAAGTGTTCA CCAACATGCT CCTGAATGTC GTGGGCTTCC TGCTGCCCCT GAGTGTCATC ACCTTCTGCA CGATGCAGAT CATGCAGGTG CTGCGGAACA ACGAGATGCA GAAGTTCAAG GAGATCCAGA CGGAGAGGAG GGCCACGGTG CTAGTCCTGG TTGTGCTGCT GCTATTCATC ATCTGCTGGC TGCCCTTCCA GATCAGCACC TTCCTGGATA CGCTGCATCG CCTCGGCATC CTCTCCAGCT GCCAGGACGA GCGCATCATC GATGTAATCA CACAGATCGC CTCCTTCATG GCCTACAGCA ACAGCTGCCT CAACCCACTG GTGTACGTGA TCGTGGGCAA GCGCTTCCGA AAGAAGTCTT. GGGAGGTGTA CCAGGGAGTG TGCCAGAAAG GGGGCTGCAG GTCAGAACCC ATTCAGATGG

AGAACTCCAT GGGCACACTG CGGACCTCCA TCTCCGTGGA ACGCCAGATT CACAAACTGC AGGACTGGGC AGGGAGCAGA CAGTGAGCAA ACGCCAGCAG GGCTGCTGTG AATTTGTGTA AGGATTGAGG GACAGTTGCT T GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG GCTCCGAGGA GGGGTGGGGA CGGTGGGGAC ATCAGGCTGC CCCGCAGTAC CAGGGAGCGA CTGAAGTGCC CATGCCGCTT GCTCCGGAGA AGGTGGGTGC CGGGCAGGGG CTGCTCCAGC CGCCTCACCT CTGCTGGGAG GACAAACTGT CCCAGCACAG AGGGAGGGAG GGAGGGCAGG CAGCGGGGAG AAGTTTCCCT GTGGTCGTGG GGAGTT GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG GCTCCGAGGA GGGGTGGGGA CGGTGGTGAC GGTGGGGACA TCAGGCTGCC CCGCAGTACC

AGGGAGCGAC TGAAGTGCCC ATGCCGCTTG CTCCGGAGAA GGTGGGTGCC GGGCAGGGGC TGCTCCAGCC GCCTCACCTC TGCTGGGAGG ACAAACTGTC CCAGCACAGA GGGAGGGAGG GAGGGCAGGC AGCGGGGAGA AGTTTCCCTG TGGTCGTGGG GAGTT GAGCTCTTCA ATATTTTAGT GAAAGCTATA GATGAGGCTC CATAGGGGAT AAAGCACAGA CACACCTTTT CAGAGGGCTT GTGGACTCTG GGCAGCCTGT CCATAGACCT CTGTCCCCAA CTGGCAAGTC AGGAAACTCC AGATTAAGGA GCCCCAATGT GGTTGAACAG CCAGGTGCAC AGATGAGTCA ACCACACAGC CAGGCCAGGG AGGGCCTTCA CTCAAGAGCC TACAGCCAGT TCACAGCCAA GCCAGGGCTA GCGCCAGGCC ACCCATAAAC TGATCTGAGA CTCTGTTTCC CTGTCTCCAT GATGATGGGA TCAGGCTTGA TTGCTGGTTT GTAGGCTTGT TATGAATCAA

GTCACAGGGA AGAGGAGCTG ATGGGCTGGG GGGACGTCCT CTGGCCCTCC TGTCTCTTCC CCAGATCCAC TGGGCCCACT CTTATCTGTT CTCTTCTGAA GGAAGGGTTT TAAGGCTTCA AAAAAAAATG TTTTGAAAGT CCCTGCCCTT TCCAGCTCCT ACCGTCTCAG CCCTGGGAGT GTAAAGTGCT GCAGATAGTT AGTAAGTCTT TGAGCAAAAC TGAGAAAGCC AGCCTGAGCC TTGACATGGG AGAAACCTCC GCCATACATC TCCGAAGAAA CGGCCGCGTG TCTCAGGGGA GCGCAAACAC CCGTACCCAG GAAACAGGAC AGCTTCTGCC ACTGTCGCCC TTGGGAGCCG TACGTGGCAT GACAAAGAAA TCCCAGGACT CCGCCTGCCC ACCTGGCCAC CCTCTGTTTA CACCTTCCGC GTAAACGCCC ACTGTTTACA TCCAAAACTC AGACACAAAA TAACCACCTC AAGAAGATAA ATAATGATAA GAAATAAATG TTACGCGAGG CAAATTTATT CACATGGGGC

TTCCCAGGCC ACTTTGTGGT CAGCCGGGAG GGACGTTTTT GCCGTCCCAC GACTCCAACG GGCAGCCGGG CCTACGCAAA CATGGAAATC TTCCAAGAGC CTCCCTGGCC CCCAGGGCTC AGAGGGTGGC AGAGCGGAGA GCGAAGGTGG CCGCAGCCTT CCCGGCCCCA CAGCCAGCCT GGCTCCAGCT GGGCAGGAGT GCAGAGCTCA GCTGGAGGCG AGGGGGAAGT GCCCAGGAGG CTGATGACAT CACTACCCAG CCCTTCAAAG ATGAGCTGTT CCCGCCGCCA CTCCAGCTCT GGCTTCTGGG CTCCGAGGAG GGGTGGGGAC GGTGGTGACG GTGGGGACAT CAGGCTGCCC CGCAGTACCA GGGAGCGACT GAAGTGCCCA TGCCGCTTGC TCCGGAGAAG GTGGGTGCCG GGCAGGGGCT GCTCCAGCCG CCTCACCTCT GCTGGGAGGA CAAACTGTCC CAGCACAGAG GGAGGGAGGG AGGGCAGGCA GCGGGGAGAA GTTTCCCTGT

GGTCGTGGGG AGTTGGGAAA AGTTCCCTTC CTTCCGGAGG GAGG GAATTCGGGA AAAAGTGAAG GTGTAAAAGC AGCACAAGTG CAATAAGAGA TATTTCCTCA AATTTGCCTC AAGATGGAAA CCCTTTGCCT CAGGGCATCC TTTTGGCTGG CACTGGTTGG ATGTGTAATC AGTGATAATC CTGAGAGATA CAGCACAAAT CTAAGCAATC ATGTGGATGA TTTCACCACT TTTCGTGGCA CAGAGCTCAG CTTCCTGGTT ACCACTCATC AACCCACTAA TTTGGTCCTA CCCAGCAATG GCTCAATGCA CAACTATTGC CCACAGCAGA CTAAAATTAC TTCAGCTTTC AAATACATTA ACACTGTGAT ATCTTGTACT ATTTTCATCG TGGGAATGGT GGGGAATGCA ACTCTGCTCA GGATCATTTA CCAGAACAAA TGTATGAGGA ATGGCCCCAA CGCGCTGATA GCCAGTCTTG CCCTTGGAGA CCTTATCTAT GTGGTCATTG ATCTCCCTAT CAATGTATTT AAGCTGCTGG

CTGGGCGCTG GCCTTTTGAT CACAATGACT TTGGCGTATT TCTTTGCAAG CTGTTCCCCT TTTTGCAGAA GTCCTCGGTG GGGATCACCG TCCTCAACCT CTGCGCTCTT AGTGTTGACA GGTACAGAGC AGTTGCCTCC TGGAGTCGTG TTCAGGGAAT TGGGATTCCT TTGGTAACTG CCATTGAAAT TGTCTCCATC TGGATCCTGT CCTTTATCCT GGCCATTCCT GAAGCGATTG GCTTCGTCAT GGTACCCTTT GAATATAGGG GTGAACAGCA TAAAACCTGT ATGCTCAATG CCACATCAAA ATTCATGGAG TTCTACCAAG ATGTAAAGGA CTGGTGGCTC TTCGGGTTCT ATTTCTGTAT GCCCTTGGTG TGCACTGCGA TCTTCTACAC CCTCATGACT TGTGAGATGT TGAACAGAAG GAATGGCAGC TTGAGAATTG CCCTCAGTGA ACATCTTAAG CAGCGTCGAG AAGTGGCAAA AACAGTTTTC TGCTTGGTTG TAATTTTTGC TCTTTGCTGG TTCCCTCTTC ATTTAAGCCG

TATATTGAAG AAAACTGTGT ATAACGAGAT GGACAAGAAC CGATGTGAAT TACTTAGTTT CTTACTGCTC ATGGATTACA TCGGTATTAA CTTGGCAACC ATGAATTCAT GTATAAACCC CATAGCTCTG TATTTTGTGA GCAAGAAATT TAAAAATTGT TTCCAGTCAT GCCTCTGCTG CTGCTGTTAC CAGTCCAAAA GTCTGATGAC CTCGGTCCCC ATGAACGGAA CAAGCATCCA GTGGAAGAAC CACGATCAAA ACAACCACAA CACAGACCGG AGCAGCCATA AGGACAGCAT GAACTGACCA CCCTTAGAAG CACTCCTCGG TACTCCCATA ATCCTCTCGG AGAAAAAAAT CACAAGGCAA CTGTGAGTCC GGGAATCTCT TCTCTGATCC TTCTTCCTTA ATTCACTCCC ACACCCAAGA AGAAATGCTT TCCAAAACCG CAAGGGTAGA CTGGTTTATC CACCCACAAC ATCTACGAAT CGTACTTCTT TAATTGATCT AATTTACATA TTCTGCGTGT TGTATTCAGC

ACTAAAAAAT GGTGGGAGCT GGGGGAGAAT GAAGACTGTT AAATGAAACC AGAAGGATAT TTACTACTTT TGCATGAAAA TAGAGCTTTC AAGTACATGG CTAGCTTTTA TGGCAGTTCT GGTGAATGTT CAATGGGAAC TGGTCACCAT GAAACTTTAG AGATTAACGA CAAGATTTTC TACTTTTTTT AAGTGATTTT TTTGTCCTTC AGCCAAACAC AATATGGGCT CAAGTCACTT TTATTTGAAA TGTCATTTGG TGCCAGTATC CCGAATTC GCCACCATGG AAACCCTTTG CCTCAGGGCA TCCTTTTGGC TGGCACTGGT TGGATGTGTA ATCAGTGATA ATCCTGAGAG ATACAGCACA AATCTAAGCA ATCATGTGGA TGATTTCACC ACTTTTCGTG GCACAGAGCT CAGCTTCCTG GTTACCACTC ATCAACCCAC TAATTTGGTC CTACCCAGCA ATGGCTCAAT GCACAACTAT TGCCCACAGC AGACTAAAAT TACTTCAGCT TTCAAATACA TTAACACTGT GATATCTTGT

ACTATTTTCA TCGTGGGAAT GGTGGGGAAT GCAACTCTGC TCAGGATCAT TTACCAGAAC AAATGTATGA GGAATGGCCC CAACGCGCTG ATAGCCAGTC TTGCCCTTGG AGACCTTATC TATGTGGTCA TTGATCTCCC TATCAATGTA TTTAAGCTGC TGGCTGGGCG CTGGCCTTTT GATCACAATG ACTTTGGCGT ATTTCTTTGC AAGCTGTTCC CCTTTTTGCA GAAGTCCTCG GTGGGGATCA CCGTCCTCAA CCTCTGCGCT CTTAGTGTTG ACAGGTACAG AGCAGTTGCC TCCTGGAGTC GTGTTCAGGG AATTGGGATT CCTTTGGTAA CTGCCATTGA AATTGCCTCC ATCTGGATCC TGTCCTTTAT CCTGGCCATT CCTGAAGCGA TTGGCTTCGT CATGGTACCC TTTGAATATA GGGGTGGACA GCATAAAACC TGTATGCTCA ATGCCACATC AAAATTCATG GAGTTCTACC AAGATGTAAA GGACTGGTGG CTCTTCGGGT TCTATTTCTG TATGCCCTTG GTGTGCACTG

CGATCTTCTA CACCCTCATG ACTGGTGAGA TGTTGAACAG AAGGAATGGC AGCTTGAGAA TTGCCCTCAG TGAACATCTT AAGCAGCGTC GAGAAGTGGC AAAAACAGTT TTCTGCTTGG TTGTAATTTT TGCTCTTTGC TGGTTCCCTC TTCATTTAAG CCGTATATTG AAGAAAACTG TGTATAACGA GATGGACAAG AACCGATGTG AATTACTTAG TTTCTTACTG CTCATGGATT ACATCGGTAT TAACTTGGCA ACCATGAATT CATGTATAAA CCCCATAGCT CTGTATTTTG TGAGCAAGAA ATTTAAAAAT TGTTTCCAGT CATGCCTCTG CTGCTGCTGT TACCAGTCCA AAAGTCTGAT GACCTCGGTC CCCATGAACG GAACAAGCAT CCAGTGGAAG AACCACGATC AAAACAACCA CAACACAGAC CGGAGCAGCC ATAAGGACAG CATGAACTGA CCACCCTTAG AAGCACTCCT GAATTCGGGA AAAAGTGAAG GTGTAAAAGC AGCACAAGTG CAATAAGAGA TATTTCCTCA

AATTTGCCTC AAGATGGAAA CCCTTTGCCT CAGGGCATCC TTTTGGCTGG CACTGGTTGG ATGTGTAATC AGTGATAATC CTGAGAGATA CAGCACAAAT CTAAGCAATC ATGTGGATGA TTTCACCACT TTTCGTGGCA CAGAGCTCAG CTTCCTGGTT ACCACTCATC AACCCACTAA TTTGGTCCTA CCCAGCAATG GCTCAATGCA CAACTATTGC CCACAGCAGA CTAAAATTAC TTCAGCTTTC AAATACATTA ACACTGTGAT ATCTTGTACT ATTTTCATCG TGGGAATGGT GGGGAATGCA ACTCTGCTCA GGATCATTTA CCAGAACAAA TGTATGAGGA ATGGCCCCAA CGCGCTGATA GCCAGTCTTG CCCTTGGAGA CCTTATCTAT GTGGTCATTG ATCTCCCTAT CAATGTATTT AAGCTGCTGG CTGGGCGCTG GCCTTTTGAT CACAATGACT TTGGCGTATT TCTTTGCAAG CTGTTCCCCT TTTTGCAGAA GTCCTCGGTG GGGATCACCG TCCTCAACCT CTGCGCTCTT

AGTGTTGACA GGTACAGAGC AGTTGCCTCC TGGAGTCGTG TTCAGGGAAT TGGGATTCCT TTGGTAACTG CCATTGAAAT TGTCTCCATC TGGATCCTGT CCTTTATCCT GGCCATTCCT GAAGCGATTG GCTTCGTCAT GGTACCCTTT GAATATAGGG GTGAACAGCA TAAAACCTGT ATGCTCAATG CCACATCAAA ATTCATGGAG TTCTACCAAG ATGTAAAGGA CTGGTGGCTC TTCGGGTTCT ATTTCTGTAT GCCCTTGGTG TGCACTGCGA TCTTCTACAC CCTCATGACT TGTGAGATGT TGAACAGAAG GAATGGCAGC TTGAGAATTG CCCTCAGTGA ACATCTTAAG CAGCGTCGAG AAGTGGCAAA AACAGTTTTC TGCTTGGTTG TAATTTTTGC TCTTTGCTGG TTCCCTCTTC ATTTAAGCCG TATATTGAAG AAAACTGTGT ATAACGAGAT GGACAAGAAC CGATGTGAAT TACTTAGTTT CTTACTGCTC ATGGATTACA TCGGTATTAA CTTGGCAACC ATGAATTCAT

GTATAAACCC CATAGCTCTG TATTTTGTGA GCAAGAAATT TAAAAATTGT TTCCAGTCAT GCCTCTGCTG CTGCTGTTAC CAGTCCAAAA GTCTGATGAC CTCGGTCCCC ATGAACGGAA CAAGCATCCA GTGGAAGAAC CACGATCAAA ACAACCACAA CACAGACCGG AGCAGCCATA AGGACAGCAT GAACTGACCA CCCTTAGAAG CACTCCTCGG TACTCCCATA ATCCTCTCGG AGAAAAAAAT CACAAGGCAA CTGTGAGTCC GGGAATCTCT TCTCTGATCC TTCTTCCTTA ATTCACTCCC ACACCCAAGA AGAAATGCTT TCCAAAACCG CAAGGGTAGA CTGGTTTATC CACCCACAAC ATCTACGAAT CGTACTTCTT TAATTGATCT AATTTACATA TTCTGCGTGT TGTATTCAGC ACTAAAAAAT GGTGGGAGCT GGGGGAGAAT GAAGACTGTT AAATGAAACC AGAAGGATAT TTACTACTTT TGCATGAAAA TAGAGCTTTC AAGTACATGG CTAGCTTTTA

TGGCAGTTCT GGTGAATGTT CAATGGGAAC TGGTCACCAT GAAACTTTAG AGATTAACGA CAAGATTTTC TACTTTTTTT AAGTGATTTT TTTGTCCTTC AGCCAAACAC AATATGGGCT CAAGTCACTT TTATTTGAAA TGTCATTTGG TGCCAGTATC CCGAATTC AACAAGAAAA GCGTTGGTAG CTCTGGTGAA TCCCAAAAGA ATGTGGCAGT TGCTAGCCAT GCTCCTGAAT ATGTATAAAC AGTACATCAT ATGACTAAGA GTTTGACTTA GGGGTTAGAT TTTATGTGTT TGAACCCCAA ATTAGTTATT TAATAGTTGG CACCCCAAAA CAAGTTACTT AACCTCACTA AGGTTCAGTT TTCCTGTTTA TAAAATGTAG ATAGTGATAG TATGTACTTT ATAGGATTAT TGTGAAAAAT AAATGAAATA TCAGATTTAT TTAGGATAAC ACCTGGCATA TGTTTGGTAT TCAGAATTAG TTGCTGCTGT TTTATTCTGC TCTCCCTTGC ATCCCACTTT TCTAAGTTGT AAACTAAATA

GTTGTACACA GATTGACAGA TTAAGAAAGG CTTGTGATTG TGCTAGACCT ATGCCTATGC CTCTGTCTCA CCAGATTCCA GGTGTATATG TGGAGGTGGG ATAGGGAGTG GAGTAAGTGG GTAAATATTA AATTGCCCAG TTGGGCACCA TCCTGAATAT TATCTCTAAA GAAAGAAGCA AAACCAGGCA CAGCTGATGG GTTAACCAGA TATGATACAG AAAACATTTC CTTCTGCTTT TTGGTTTTAA GCCTATATTT GAAGCCTTAG ATCTCTCCAG CACAGTAAGC ACCAGGAGTC CATGAAGAAG ATG GATCTTCATG TGGAATGACT GGTTTCATTC AATAGACTTA ATTCAGCAGT CTGTGGGGAA GAGCAAGGTA TGATAGAATG GTTCCTCAAG TGCTTCAGAT GTGAAGTGGG TTTAAATATA CTGTCCCTGT CTTCTTCAGA GTTTTGGTAA AGATAAAATA GGACACTCAT TTAAAAGCAA TCTTTGCAAA TGACAAGCCA CTATAGACAT TAATAGAGTT TTCATTTCCA

GTATTATCAT TAATATCAGA TCCTGGAAGA AGGTTGAGCC TTGACCTAGA GCAAAAAAAC AGAAGAATTA GTAAAGGAAT CCTGGAGAAA GCCCCTGCTG TGTATTTAAA GGAGAAAGGG AGATCATGTT GGGAAATTAT AATATTAAAA GTAAACAAAA GCTAGGAAGT AAAATAAAAT AAATTATATG GCCTAGATCC CCATAAGTAA TGGTTTAACT TCTGCCTTCC TGTGTTCTGA GCCAGATTAG GGCACAGTAG AGAAAGAGGA GTCTCTGAAA ATGTTTCCAA TTTCGCTGGT CAGACAGCGG ATCATCAGTG AATCAGATGA AAATTTGTGG ATTTATGCAC TAACTGATCA GCAGGAAATT AAACAAGAAA AGCGTTGGTA GCTCTGGTGA ATCCCAAAAG AATTTGGCAG TTGCTAGCCA TGCTCCTGAA TATGTATAAA CAGTACATCA TATGACTAAG AGTTTGACTT AGGGGTTAGA TTTTATGTGT TTGAACCCCA AATTAGTTAT TTAATAGTTG GCACCCCAAA ACAAGTTACT

TAACCTCACT AAGATTCAGT TTTCCTGTTT ATAAAATGTA GATAGTGATA GTATGTACTT TATAGGATTA TTGTGAAAAA TAAATGAAAT ATCAGATTTA TTTAGGATAA CACCTGGCAT ATGTTTGGTA TTCAGTAATT AGTTGCTGCT GTTTTATTCT GCTCTCCCTT GCATCCCACT TTTCTAAGTT GTAAACTAAA TAGTTGTACA CAGATTGACA GATTAAGAAA GGCTTGTGAT TGTGCTAGAC CTATGCCTCT CTCTCACCAG ATTCCAGGTG TATATGTGGA GGTGGGATAG GGAGTGGAGT AAGTGGGTAA ATATTAAATT GCCCAGTTGG GCACCATCCT GAATATTATC TCTAAAGAAA GAAGCAAAAC CAGGCACAGC TGATGGGTTA ACCAGATATG ATACAGAAAA CATTTCCTTC TGCTTTTTGG TTTTAAGCCT ATATTTGAAG CCTTAGATCT CTCCAGCACA GTAAGCACCA GGAGTCCATG AAGAAGATGG CTCCTGCCAT GGAATCCCCT ACTCTACTGT GTGTAGCCTT

ACTGTTCTTC GGTAAGTAGA GATTCAATTA CCCCTCCCAG GGAGGCCCAA ATGAATTTGG GGAGCAGCTG GGGTAGGAAC CTTTACTGTG GGTGGTGACT TTTTCTAGGA CATGTGCAAA CTATTGGGCA TTTCCCAGGG ACTCTGTAGT GGAGCCAAGC TAGAAAGCAG AGGCAAGTGG GCTGAGCAAC ACCTAAGGAG GAAGCCAGAC TGAAAGCTTG GTTCCTTGCA TTTGCTCTGG CATCTTCCAG AGTGCAAATT TCCTACCAAG GTAATGAGGG TAGAGGAGAG AAAGAAGCTC TTTCTTCCCC TGATTCTCAT TCCTGAAAAG ACGGTTGGTC CTTAAAATTC CATGGATGTA GATCTTATCC CCACACCCAG ATTCTAGTCC TCTGGAGATA AAGAAGACTG CTGGACACTA ATGTATCCTC TCTGGACTTT TGCAGCTCCA GATGGCGTGT TAGCAGGTGA GTCCTCTGTT CTTGTTCCCT TGGTGTATCA ACATGTCTGG GCATTGCTTT CCTCTCACTA TTTTCTTCGT CCCATCACTT CTGCTTTCTA ATGAGCATGA ATCTGTTCCT TGGCCAGACT ACTTTCCCTC TCCACCTTGC CTTGTCTTTC TTTTTTTCCC TGATTCATTG CATTCTCTCA AGTCATTCTC TCCTCTGTTT TAGTCAATAA CCATGTCTGT TGCACATATA CATGTCTCAT TCTCTCTCCT AGACACTTTG GCATGATCTC GCTCAATAAT TACATTATTA TTATTATTGC CATTTTATAA TTGAGGATGC TGAAACTCAG TGATTTTCTG GTGGTTACAT GGCTAAGGAA CTGGATTTCA ACGTAAGTTC CTTGGATCTA AGTCCAGTTC TCTTCTGACT ATATCACCCT TTTGTTATCA CCATGTATCT ACTTCTTTGG TCTCTGTTCA AATTTGCACT ACATCCCCTT GTTCCAGGAA GCCATTCAAG ACTGACTTTC

TTAGTGCCTC TCACTACTTT CTGGAACTGA CATATGTTTT TCACTCTGTA TATACTTACA ATTAAATAGT CATAAATATT CAGAGCTTGG AGAAACCTTA TATTTCATCC AGTCCAGTAA ATTTATCCAT CCATAATTCA CTCATTCATT CACATAATAA ATATTTAATG TAACAATGGT TGAACATGGC AGACAGTGTT TCTACCTCAA AAGAGATTGC AGTCCTCATT TACAGATACT GAATTGAAAT TAACAGAAGT AGAGTGAGTC AGCTCAAATC ACATAGTGAA TTGGTTTCTT TGTTTTTAAA TCTCCTGCAT ATGTGTCCTG TCTTTCTCCC TGTGTTGGGC GTTCCCTGGG GCACCAATAC TAATTTCTCC TTCCCCTAGA AATCAAAACA GGGTCTTATC ACCAACAGAA TAAGGACAGG TTGACCACTG ATTGTCAGAA TATTGCTTCG TTTGTACTTT TAAGCCTAGA CAGTTTTCAA TGACTTTTTT TCTCTCTACA TGTCTTTTCA TATTTTTATC TTCTTGAAGT CCCTCAGAAA

CCTAAGGTCT CCTTGAACCC TCCATGGAAT AGAATATTTA AAGGAGAGAA TGTGACTCTT ACATGTAATG GGAACAATTT CTTTGAAGTC AGTTCCACCA AATGGTTCCA CAATGGCAGC CTTTCAGAAG AGACAAATTC AAGTTTGAAT ATTGTGAATG CCAAATTTGA AGACAGTGGA GAATACAAAT GTCAGCACCA ACAAGTTAAT GAGAGTGAAC CTGTGTACCT GGAAGTCTTC AGTGGTAAGT TCCAGGGATA TGGAAATACA GATCTCTCAT GTGAGGGATG GCTCATCTGA AGATGGGAAA AAACAGGTTA TTCCAAGGGT TAGGACACCA GAGTGGGATT CAAGGCCTCT CATTTTTAAG ACCCCTGCAT TGGCTGGGCA CAGTGGCTCA CGCCTGTAAT CCCAGCACTT TGGGAGGCTG AGGCAGGTGG ATCACGAGGT CAGGAGATCG AGACCATCCG GCTAACATGG TGAAACCCCA TCTCTGCTAA AAAATATATA TATATAAAAT TAGCCGGGCG TAGTGGTGGG CACCTGTAGT

CCCAGGTACT CGGGAGGCTG AGGCAGGAGA ATGGTGTGAA CCCAGGAGGT GGAGGTTGCA GTGAGCTGAG ATCACGCCAC TGCCCTCCAG CCTGGGCTAC AGAGCAAGAC TCCGTCTCAA AAAATAAATA AATAAATAAA AAAGACCCCT GCATCTGTTT TCTTCTACCC CCTTCCCTTT TGATTACTTG TATGCCTTCT TTCAATATTC TAGTCATCTC TCAATATTAT TCCTCCACCC TATTTTCCTC TATCTTTTCT GCCTAGATTC AGGTATATAT TATGTGGTCA AACAGCATGA CATATATGTG AACATTTCAA AGAGCTGTGT ATCTGGAATA GGATCAAAAG GTTTGACTTA AAGTTTTGCT CTGCATAATC CATATGGCAG GACCTGAATA TTAGGTTGTA CTCTTCGTTA TGAAACATAT CTGGGTACAT TTCCTTATGT CCTCTGTTGT TACTTAAGAA CACATATTTC ATGCTTGTTT CATTTTTATC ACTCCTACTG CCAACAAATA GCATAGCATG CTTAGGCACA

TGTGGCTTAA TTAGCAAATG TTGAATAAAC AAATTAATGA TTTTGAATAG TGACCAATAG GTCTCTTTTA TACTCTATAT TTTTCTCTTG AGTGAAAAAA AATGTTTCAA CCTCCATATG TAAATTCCAA ACACAAACTA AAGCAATGTA GAATAGCTTC TTTATTCCCT GGAGTAGGTT CTAGAGAAGT CCTAAAGGAT TGGTCCTAAA TTAATTATGC TTATTATGCT AGCGATATTT CCTTTCAAAA TTCTCCTTTA ATGAATGCTT TTTAATTTTT ACAAAAGCAT TAACCATAGA ATGTGATTCT TGTCTTTCAC TGACTCATTA GTGACAAATA TTTGTTGAGT ACCTACCAAC TCCTAAGTAT TGCTACCAAC TCCTAAATAC TGTGTTGGGC ATTCAGAATA GAATGTAGAA CTAGACAGGG TCCCTGACTT CTTGGAGCAC AGAGCAGTAT GGGAAGAGGA CATTAAATAA AGAATTACAT AAGTAATTAA TTTAAATTAT ACATGTTTTG AAGAAGTTTT TTTTTGACAA CTATAATTAA

CACTAGAACT GGGAAGTTTC TATAAGGTAA GAGAGGACAA AATAGACACT CTCCTAAGCT AAAATTCCCA AGAAAGACTG TTTATTTTCC CCTAACTAAC TAGAACTAGC AACAGAAGAT CTGAAAGGAA TTCTGGCTTT CAAGTGTTCC ATGTATGGAC TCATCAGGGA GGTCCGAGAG GCTTTGTGGC CCCAGACTGA CTTTTCAGGA GGGGAAAGGA TTTATCAATA CACAAGACAG GCTCTAAGCA TTATTTTGTG CCCTTTAAAA ATCCACTTTA TGAGCCAAAA AGTGAGTTAA TGATAATTCA TAGTTTCTGA CACATGCTCT ATGCGTGGCT CTCTTTTCTC TATTCATTCT CTCTCTCTTC ATTTATTGTT AAATAAATAA TGTAATGAAT GTTCTTCAGA CTGGCTGCTC CTTCAGGCCT CTGCTGAGGT GGTGATGGAG GGCCAGCCCC TCTTCCTCAG GTGCCATGGT TGGAGGAACT GGGATGTGTA CAAGGTGATC TATTATAAGG ATGGTGAAGC TCTCAAGTAC TGGTATGAGA

ACCACAACAT CTCCATTACA AATOCCACAG TTGAAGACAG TGGAACCTAC TACTGTACGG GCAAAGTGTG GCAGCTGGAC TATGAGTCTG AGCCCCTCAA CATTACTGTA ATAAAAGGTG AGTTGGTAAA GGAAAGGAAA AGCATCCATA GCAGGGGAAG GAAGAGAGAA CTTCTGAGCC TGAGCAGTTG CAGCTTGTAG AAGGGGGGCA CCTGTGATAC ACTGGAAAGC CTACCAGACT TGCAATGAGG AGACCTGGGT GATAGTATAT ATCTCAATCT CTGTTTCAAA GCCTTGACTT GTTAAATGGT GATAGTAATA CCTGCTTGCA CTATGAAATT TTTATGAAGA TTAATGTGGT AATATTTGTG AAATGACTTT GTAAACTGTT AAGCACTACC CAAGCATAAC AGATTGTGAT TACTATTTTG ATCTCAAAGT CATCTGTTGC TCCTGGGGGA ACACTTATAT TTATCAAATT GAAAAAAAGT TTCAAAGTTG AATGAAGAAA GGATATAAAG AGCTTGAGGA GCCCATTCCA

GCTTAGGAGG GCTGGGAAAG GAAACCAGCA AGTCAGTAAG CTGTGTGCCT GTGTATTGAG GGAGGAGGGA ATGGACTTGA TATGGAGAGG GTAGGGAGGT GGACTGCCTC TATGGCCTGT AAGAAAAACT GCTCTCTCCA AACTCTTTAT AAGAGAGGGA GCCTGTGAAG TATTCACTTT TGAAGGAGAA AGTTAGACTT TTCCTTCACA CACTTTGTAC ATAATAATGT TTAAAAAAGC ATGAGGTCAA AATACATAAT TAAGTCCTAG CAGTTCTCTG TTAACTAATT TGAGACTGAA GTGCTATGTA CTTGTCTCTA GGCTTCCAGT ATCTTCATCT GTAAAACAGA ATATTTGGTC TAGATTCCAT TAGAATCATT TGATAACTTA AAAAATATAT TGATGCTCAT GTCTCATTTC TTGAGATTCT GATTTAATTG GTTTGGGGTG CAGCCTGGGT ATACGTATTT TTCATAGGTC TTTCACATAA TGGTAATGGG TAGCCAATAT TGAGAATCAC TTGTCTAGGT GATCTTTAAA

TGATTTCTGG ATGTAATATT CTGAGGCTCT ATAATTTGAG ACTAATCACA AAAATCGGTA CAGTTTATAA ACAGACTAAC AGAACCACAA AATAATAGAA TTGGAAGGCA ATTTAACTAG TGCAATTTCT TCATTTTGCC TAACAGGCAT GTAAGAAATG ATGATTGATT GAGTAATAGG CATTGATGAC CCCTGTCCTC ACTTTGTCCC CTTTCCACCC CTTAATTATA TGTGAATTCT GGTCTTGTCA TTTCGAATAA GGGGTTTATC TTTCCTATTG TCTTCCCCTC TGGGCACGGC ACACTGGCTA CTGGAGTTAA GAGGAAATGC TTAGGACTCC CTGTGGCTCC AGGGAGCACC AACAGAGCAA CTCAACCTAG TGTTAATCTG AGTGTTTTCT CTGTGCTTCT GGATGCCACA TCACGCTAAA AATGAAGGAC AAAGCTTGGT CTTTCTCTTA GGGAGGATGA AACTCTGAAC CTCATTTTTC AGTTCCCAAG ATGAATTATG TTTCTCATTG CATCTGTGTT CCACTACAGC TCCGCGTGAG

AAGTACTGGC TACAATTTTT TATCCCATTG TTGGTGGTGA TTCTGTTTGC TGTGGACACA GGATTATTTA TCTCAACTCA GCAGCAGGTC ACATTTCTCT TGAAGATTAA GAGAACCAGG AAAGGCTTCA GACTTCTGAA CCCACATCCT AAGCCAAACC CCAAAAACAA CTGATATAAT TACTCAAGAA ATATTTGCAA CATTAGTTTT TTTCCAGCAT CAGCAATTGC TACTCAATTG TCAAACACAG CTTGCAATAT ACATAGAAAC GTCTGTGCTC AAGGATTTAT AGAAATGCTT CATTAAACTG AGTGAAACTG GTTAAGTGGC ATGTAATAGT AAGTGCTCAA TTAACATTGG TTGAATAAAT GAGAGAATGA ATAGATTCAT TTATTAGCAT TTGTAAAAGA GATGTTCAAT TTCAATAAAA TAAATATAAA ACCATGTAAC AGAATGCTTC TGAGTATTCA AGGCTTGCTA GTTTGTTTGT TTGTTTTCTA CTAAAGGCAA GGACCATGAA GTTCTAGATT GGAAATGTCC TCTCTTGACT

ATTGCAAGTG CGATCTAGGA ATGAAAAGAC ATAGGAGGAT GCCAGTGAGG TGGATCATTT TTATGCTTCT TCTTCAGCTT ACTAAATATG AACTTTCAGT TCTTGGCAGA ATCAGGGACA GTCTCAAGAC ATAGGACTCT CAGGATGAAG TAGAGTCCAG GATTCCTCTG TGATTGTTTT GCCCCTCCCA AATTTATATC TTGAACTTAT GTCTTGTATC TTTATACAGC ACCTGAACCA AGCATTTTGG AGAAATTCCA GCTAATAATA ATAACCAAAA CCTTCGGCTC TGAAAACAGT CCAGGACTGA ATAAGATCTT GGGCAAAAGA ACTAGACAGT TTTGGTTTAT TTTCCCTTTC ATTTTATGTC TTCATCATAG TCATTGGAGG CTCATTCTTC TTGTCATGGA GTAAATGGGA TTAAAGTTC TACTAAGAGT CTCCAGCATC CTCCACCTGT CTACCACCGA GCATGGGCCT ATATTTGAAG CCTTAGATCT CTCCAGCACA GTAAGCACCA GGAGTCCATG AAGAAGATGG CTCCTGCCAT

GGAATCCCCT ACTCTACTGT GTGTAGCCTT ACTGTTCTTC GCTCCAGATG GCGTGTTAGC AGTCCCTCAG AAACCTAAGG TCTCCTTGAA CCCTCCATGG AATAGAATAT TTAAAGGAGA GAATGTGACT CTTACATGTA ATGGGAACAA TTTCTTTGAA GTCAGTTCCA CCAAATGGTT CCACAATGGC AGCCTTTCAG AAGAGACAAA TTCAAGTTTG AATATTGTGA ATGCCAAATT TGAAGACAGT GGAGAATACA AATGTCAGCA CCAACAAGTT AATGAGAGTG AACCTGTGTA CCTGGAAGTC TTCAGTGACT GGCTGCTCCT TCAGGCCTCT GCTGAGGTGG TGATGGAGGG CCAGCCCCTC TTCCTCAGGT GCCATGGTTG GAGGAACTGG GATGTGTACA AGGTGATCTA TTATAAGGAT GGTGAAGCTC TCAAGTACTG GTATGAGAAC CACAACATCT CCATTACAAA TGCCACAGTT GAAGACAGTG GAACCTACTA CTGTACGGGC AAAGTGTGGC AGCTGGACTA TGAGTCTGAG

CCCCTCAACA TTACTGTAAT AAAAGCTCCG CGTGAGAAGT ACTGGCTACA ATTTTTTATC CCATTGTTGG TGGTGATTCT GTTTGCTGTG GACACAGGAT TATTTATCTC AACTCAGCAG CAGGTCACAT TTCTCTTGAA GATTAAGAGA ACCAGGAAAG GCTTCAGACT TCTGAACCCA CATCCTAAGC CAAACCCCAA AAACAACTGA TATAATTACT CAAGAAATAT TTGCAACATT AGTTTTTTTC CAGCATCAGC AATTGCTACT CAATTGTCAA ACACAGCTTG CAATATACAT AGAAACGTCT GTGCTCAAGG ATTTATAGAA ATGCTTCATT AAACTGAGTG AAACTGGTTA AGTGGCATGT AATAGTAAGT GCTCAATTAA CATTGGTTGA ATAAATGAGA GAATGAATAG ATTCATTTAT TAGCATTTGT AAAAGAGATG TTCAATTTCA ATAAAATAAA TATAAAACCA TGTAACAGAA TGCTTCTGAG TAAAAAAAAA AAAAAAAAAA AAAAAAAA TCTCAATATA ATAATATTCT

TTATTCCTGG ACAGCTCGGT TAATGAAAAA ATGGACACAG AAAGTAATAG GAGAGCAAAT CTTGCTCTCC CACAGGAGCC TTCCAGTGTG CCTGCATTTG AAGTCTTGGA AATATCTCCC CAGGAAGTAT CTTCAGGCAG ACTATTGAAG TCGGCCTCAT CCCCACCACT GCATACATGG CTGACAGTTT TGAAAAAAGA GCAGGAGTTC CTGGGGGTAA CACAAATTCT GACTGCTATG ATATGCCTTT GTTTTGGAAC AGTTGTCTGC TCTGTACTTG ATATTTCACA CATTGAGGGA GACATTTTTT CATCATTTAA AGCAGGTTAT CCATTCTGGG GAGCCATATT TTTTTCTATT TCTGGAATGT TGTCAATTAT ATCTGAAAGG AGAAATGCAA CATATCTGGT GAGAGGAAGC CTGGGAGCAA ACACTGCCAG CAGCATAGCT GGGGGAACGG GAATTACCAT CCTGATCATC AACCTGAAGA AGAGCTTGGC CTATATCCAC ATCCACAGTT GCCAGAAATT TTTTGAGACC AAGTGCTTTA

TGGCTTCCTT TTCCACTGAA ATTGTAGTGA TGATGCTGTT TCTCACCATT CTGGGACTTG GTAGTGCTGT GTCACTCACA ATCTGTGGAG CTGGGGAAGA ACTCAAAGGA AACAAGGTTC CAGAGGATCG TGTTTATGAA GAATTAAACA TATATTCAGC TACTTACAGT GAGTTGGAAG ACCCAGGGGA AATGTCTCCT CCCATTGATT TATAAGAATC ACGTGTCCAG AACACTCTGA TTCACAGCCA AGGATCCAGA AGGCCAAGGT CTTGTTAAGG GGCTACTGGA AAAATTTCTA TTCTCTCCAC AGCCTGCTGG TTTT AAGCTTTTCA AAGGTGCAAT TGGATAACTT CTGCCATGAG AAATGGCTGA ATTGGGACAC AAGTGGGGAC AATTCCAGAA GAAGGGCACA TCTCTTTCTT TTCTGCAGTT CTTTCTCACC TTCTCAACTC CTACTAAAAT GTCTCATTTT CAGGTTCTGT AAATCCTGCT AGTCTCAGGC AAAATTATGC TCCAGGAGTC TCAAATTTTC TTATTTCATA

TTAGTCTTTA TTTAGTAGAC TTCTCAATTT TTCTATTCAT CACAAGTAAA AGCCTGTTGA TCTTAATCAG CCAAGAAACT TATCTGTCTG GCAAATGACT TATGTATAAA GAGAATCATC AATGTCATGA GGTAACCCAT TTCAACTGCC TATTCAGAGC ATGCAGTAAG AGGAAATCCA CCAAGTCTCA ATATAATAAT ATTCTTTATT CCTGGACAGC TCGGTTAATG AAAAAATGGA CACAGAAAGT AATAGGAGAG CAAATCTTGC TCTCCCACAG GAGCCTTCCA GGTAGGTACA AGGTATTATT TTTTTCTACC CTCAGTCACT TGTGGCAGGG GAAGTCATAG TCACGGTGCT TAGGAGATGA AACTTTATTG ATTTAGGCAT GGATCCATCT AGTTTAATTA ATATATTGGG TATGAGGAAG CTACTTGCTG TACTTTCCAT GTGGTTCTCT CTCCCTGGAG AGGAACATTT TTACTCAGCT TGCAAACTGG AAATAGATTT TCTCACATTA GAAGCTCATT TTCTGGGTAT GAGACAGGAG

AGTTCATACT GTGTATGTAG ATCTCTGGCT TCTGGGTCTG ACATGTGCTG AGGGACACAT ATCCTTCACA CATGCTTTTA TAAATACTTG ATAAAGTAAC CTGCTTCTTG ATTGGTCTTT ATAATCCATA AGCTGTGGGA TGCTTCTCTG AAGATGAAAA TAGTAATAGA GTCCCATCTA GCTATTCAAA GCCATTCCTT CATTGTATTC TGTGCACATG AAGTTGGGGT TTGTTACTGA CAAAATATAT TCAGATACAT TTCTATGTTA AAAGGATTGT GAGATGCATA GGTAAATGTG TTTATTTTCA GTTTTACTTG TCAACATAGA TGAATGAGAA AGAACTTGAA AGTAACACTG GATTAAGAAT AGGAAAATTT GGCATGGATT TTGCTCCATT TTGTCCCATC TAATCACTTG GATAGTGTTC AGGTGTTCTT GGTCAGTTAC TTGGATGCTC TGAGCTTTAG TTTCTTGGTG ATTACAATGA AGATTTGAAT TACAGGATGG CTTTGAAAAA ATAAACAAAA CTCCCCTTTC TGTCTGTCGA

GAATGTTGCA CAGGGAGTTA CAGAATGTTC TCATGACTGA ATTGCTTTTA AATTTCACAG TGTGCCTGCA TTTGAAGTCT TGGAAATATC TCCCCAGGAA GTATCTTCAG GCAGACTATT GAAGTCGGCC TCATCCCCAC CACTGCATAC ATGGCTGACA GTTTTGAAAA AAGAGCAGGA GTTCCTGGGG GTGAGTGAGC CTCCTCCAAC TTTGACTAGA GTAAGGGTTG GGTCTAGAAA AGAATATTGA GTTGCATCAA CTGTTTTCCC ACTTGGATTC ATGAGAGGTG TTAGGTCCTT TAAAAAACAT GGTAGATAAA GAGTTGACAC TAACTGGGTC CTTTTGGGAA GAGCCAGAAG CATTTCCTCA TAAAGACTTT AAATTGCTAG GACGAGAATG GCCAACAGGA GTGAAGGATT CATAACTTTA TCTTTACTTA GATGTAAAGA ACAATTACTG ATGTTCAACA TGACTACATA CATAAAGGCG CATGGAGAAA AGTATTGGCC TTCCATGCAT TAGGTAGTGC TTGTATCAAT TCTTATAGTG

GCTAGGGTAT CCTGGAAAAT CTTACGTGTG GATCATTTCT CAGGACAGTC TAGGACACTA ACGCAGTTTC TCATGTTTGG CTTCTATTAT TAAAAAATGA TACAATCTCG GGAAAATTTT TTTGATTTTC ATGAAATTCA TGTGTTTTTC TATAGGTAAC ACAAATTCTG ACTGCTATGA TATGCCTTTG TTTTGGAACA GTTGTCTGCT CTGTACTTGA TATTTCACAC ATTGAGGGAG ACATTTTTTC ATCATTTAAA GCAGGTTATC CATTCTGGGG AGCCATATTT GTGAGTATAT ATCTATAATT GTTTCTGAAA TAACACTGAA CATAGGTTTT TCTCTTTCTC AGATCTAACC AGTTGTTTAT TCCCAGTATT AAGATGATAT TTATAATTCT TAATTATAAA TATATGTGAG CATATATAAC ATAGATATGC TCATTAACAA CAACAAAAGA TTCTTTTTAC AATTAACGGT GGGTTAAACA TTTAGCCCAC AGTTTTATCC CATGAGAAAC CTGAATCTAA TACAAGTTAA ATGACTTGCC

TAAGGGCCAC TTGACTAATA GTAATTGAAC CTAAACTTTC AGAATCCAAC TCCAGGAACA TACTTCTAGC ACTATTCATC AATAAAGTTA TATGATAAAT ACATACAACT TTATCTGTCA ACTAAAAATA ACAACAGAGG CTGGGCATGG TGGCTCACAC CCGTAATCCC AGCACTTTGG GAGGCTGAGG CAGGTGGATC ACCTGAGGTC AGGAGTTTGA GACCAGCCTG ACCAACATGG TGAAACCTCA TCTCTACTAA ATATAAAAAA TTAGCTGAGT GTGATAGTGC ATACCTGTAA TCCAGCTACT TAAGAGGCTG AGGCAGGAGG CTTGTTTGAA CCTGGAAGGC AGAGGTTGCA GTGAGCTGAG ATTGTGCCAT TGCACTCCAG CCTGGGCAAT AAGTGCGAAC TCTGTCTCAA AATAATAATA ATAATAATAG AAAATAAAGT TGTCTTCATG AAAAATGAGG AAAGAGATTG CTGGGGTGAG AAACATTAAG ATCAATGGGC ATATGGTGAC CTTCTATGCC CTAGAAACTC TTTTANGGTA TTTTCTCCTG GTATCTCTTT TACNCATCGT TCTATCTGGA AAAATAGGTG GATGAGTGAG ATAATAACGG TATATACTTT TTAAAGGTCT AATTGACATA TATAAATTGC AAGTATTTCA GATGTCAATT TGCTAACCTT GACACACATA GACACACATG AAAACATCAC CACATTAATA CAATGTATGT ATCCATCATT CCAAAAGCTT CCCTGTGTAT CTTTGTAACT CTTTCTTCCT CCCTCCACTC CTTGTCCTCT CGTTCCCAAG AAAACATTGA TCTGCTTCCT GTGAATATAA ATTAACTTAC ATTTTTTAGA GCTTTATATA AGTATGTTCT CTTTACTGTT TGTCTTCCTT CGCTGCACAG TTATTTTGAG ATTCTTCAAG TTTTTTCTTT ATATCGATAC TTCATTCACA AGAATATATT TTAATTCTAG

ACTATGTCAC ATTGACTTTG TCGTCTGCTA AATCCTTAGT GCTCAGATGA CTTGTTCAGG ACTCTCCTTG AACCTGTACC TCTGTTANAT TGAAACTTGT CTCTACTGTC TTTTTATTTC AAACACAGCT TATTAGGTGT CTCTCAACCC ATCAAACNCA CAATCTGAGT CTTTAGGAGA TTGCTTTGAA TTTGTGCTAT TGACTTATAT NTATATNAAA TNTGTAAATG TTTGGTAAAA ATATCATCAT GTACNTTTTC ATAATTACGC TATNTNCACA TGATATATGT CAGACTCTGG AAATATGCAT GCCACAGACA CGTGTTTCTT GCCTAAAGGG GCTGATGGAA GACNCACATA C AATAGACG ATTGCAGTAG AATGAGAGTG GTGGTCTAAN CAGTACATGT CCTGATGTTG CTCGGACAGT TACTACNCCA AGAGTACCCC CTGCATTGTC AGGGTTAGCA TCTCCTGGAA GCCTCATGTA AATGAAGAAT TTCATGCTCC ATCCAGGACC TAATGAATAA GAATCTGCAT TTTAGCAAGA

CCCTCATATG ATTCATATAC ACTTTTTTTT TTTTTTTTTA GATGGAGTCT CACTCTTGTC GCCCAGGCTG GAGTGCAATG GCATGATCTT GGCTCACTGC AACCTCTGCC TCCCGGGTTC AAGTGATTCT CCTGTCTCAG CCTCCCTAGT AGCTGGGACT ACAGGTGCAT GCCACAGTGG CTGGCTAATT TTTGTATTTT TAGTAGAGAC AGGGTTTCAC CATTTTGGTC AGGCTGGTCT TGAACTCATG ACCTCCGGTG ATTCCCCCGC CTCGGCTTCC CAAAGTGCTG GGATTACAGA CATGAGCCAC CACACCCGCC TTATTCGTAT ACNCATTTAA TTCTGAGAAG CACTCTATAG AAAATAAGAA TAAGAAAATA TTGGGCTCAC AGGTGACATT AATAAGTAAC TTTATCGAGT ACCCCAAATT TTACCTATGT TTGGAAGATG GGGTTAAAAG GACACATTGA AAACAAGAAC TCATTGTGGC TTTTTTTTCC TCCTTTTTGA ACAGTTTTCT ATTTCTGGAA TGTTGTCAAT TATATCTGAA

AGGAGAAATG CAACATATCT GGTGAGTTGC CCGTTTCTGT CTTTGTCCAT CCTTGAAAAG ATAAGAAGAA CAGAGTTTTA AGAGTCTTAA GGGAAACACA TCTTTGTCTC CTATATTACT TGTGAATGTG GATATATGAT TTTGTTTCAA TCTATTTTGT GTCCTAAGGC TTTTTGCAAC AGAAGTTGGA TATATCATTA GAAACATAAA TTGTACCATT TAACATACAT GAAGTTTATG TTTACCTTGA CGTTCTTCTA AAAAGTGTCC TACACCGGCA TTGTCCTTGT AGGCATATTC ACATGATCAA ATAAAATAAT TAGTTTTCAA TTAAGGAGAA TATTTGAGGA AAGACCGTAC GTGTTCATGT GGTTCCTGAA GGCAGTCCAG TGAGAAAGTA ATATATGCTT CATTAAACAA TGCGGACATT TTCAGGGTTT CCCTTTTTAA CCAAAATTTG GAAGCAATGT GGAATTTACT GGATGCATCC AGCCCTGAAA TGAAGATAGG TTTATTGAAT GTGCCAGCAA GTGCAGGCCC AGGTCTGAGT

GTTCTTCATT ATTATCAGGT GAGAGGAAGC CTGGGAGCAA ACACTGCCAG CAGCATAGCT GGGGGAACGG GAATTACCAT CCTGATCATC AACCTGAAGA AGAGCTTGGC CTATATCCAC ATCCACAGTT GCCAGAAATT TTTTGAGACC AAGTGCTTTA TGGCTTCCTT TTCCACTGTA TGTATTTTTT TTTGTGTGGG AAGACTAAGA TTCTGGGTCC TAATGTAAGT AAGAAGCCCT CTTCTCCTGT TCCATGAACA CCATCCTTTT CTGTAACTTC TATTACACAG TATAGTGGTT CTGTAAGTTC ACACAGCCCA GGGAGATGCT GGCTGCCCAC TCCCCTCAAC CCAGGCAAAT TCCTCGGGGT TAAAGTTATC TACTGCAAGT GACGATCTCT GGGTTTTTCT GTGCCTGTGT TTGTGTGTGT GTGTGTGTGT GTGTGTGTGT GTATGTGTCA CTTTAAAAGG ACTGGTCAGA TGGTAGGGAG ATGAAAACAG GAGATGCTAT AAGAAAATAA ACTTTTGGGG CGAATACCAA TGTGACTCTT

TTTGTTTGTC ATTTGTTGCT GTTCAATAGG AAATTGTAGT GATGATGCTG TTTCTCACCA TTCTGGGACT TGGTAGTGCT GTGTCACTCA CAATCTGTGG AGCTGGGGAA GAACTCAAAG GAAACAAGGT AGATAGAAGC CCGATATAAA ATCTTGAATG ACAGGTTAAC GAATTGGAGC TTTATTCCTT AAAATATGGC CTGGGTTTTC TGAAACATTT CTTCCAGAAA ATAGTTTCTC CAAGTTTTAT TACTTTGGTT TACAAATCTC ACATTTAAAT CACATTTTAT ACCATAAGTA GCACACATTT CATAATATTC CTCTGAATGA GGGTTGGGAT AATAGGACTG ATATGTTAGA AATGCCTTAA AGTGTGTGGA GCATGAGAGA TGGATGTACA GAAGGCTTGT GAGGAAACCA CCCAGGTATC TGGCCTTGTT TTCTGCCCCA GAACTAGCCG CCTATTCCTG TTTCTGTTTT ATTCCTTTGT TTCTTGACTT TTCCTTTCCA ACTTGCTCTA AAACCTCAGT TTTCTTTCCT TTCTGATTCA

TGACTACCAA ATGTTTTCAC TTGCCTCACC CGTCCATTAC ACCTTTGATA AGAACCACCA GACCTTGTGC TCATGTACTT GCCCATGTCT GATGGAAGAA ACATACTCTC TCCATCTGTC CACTTTCCTG AGGCATTCAA GTCTAGCCAC CTTTTAAAAT CACTCTCCTC CAGGCTGGGC ACGGTGTCAC GCCTGTAATC TCAGCACTTT GTGAGGCTGA GGAGGGCGGA TCACTTGAAG TCAGGAGTTC AAAACCAGCC TGGCCAAATG GCAAAACCAA ATCTTCTTCA ATTATAACCA AATCTTAAAC CAAATCTCTA CTAAAAAATA CAACAAAACA AAACAACAAC AACAAAAACA GAAAAGGAAA CATTAGCCCA GCGTGGTGGC AGGTACCTGA GGTTCCAGAT ACTTGGGAGG CTGAAGCAGG AGAATCGCTT GAGCCCAAGA GATGGAGGTT GCAGTGAGCC GAGATCATGC CACTGCACCA CAGCCAGGGT GACAGAGCCA TACTTCCCAG CACATTGGGA

GGCCAAAGCT GAAGAATAAT TTGAGGTGAG GATTTGGAGA CCAGCCTGGC CAACATGGTG AAACTCCGTC TGTACTAAAA ATATAAAACT TAGTGGGGCA TGGGGGCACA CACCTGTAAT TTCAGCTACT TAGGAGGCTG AGGCAGGAGA ATTGCTTGAA CCCGGGAGGC GGAAGTTGCA GTGAGCCAAG ATCGTGGCCA CTGCACTCCA GCCTGGGTGA CATAGTGAGA TTCTGTCTCA AAAAAAATAA AAGAAATTTA AAAAATCACT CTCTTCCAAA GATAGATAAA TAAGACAGCA GATATACTAA GGAATAACCT CACCAACTTG TCATTGACTG ACATGATTTC TTTTGGCCCA CTTGGCCAGC TAGTCTGGTT TGGTTTTCTG GAAATGAAAG AAATAATCAG AGTTTAATGA CAGAGAGCGT GAGACCCAGA AAGACAAAAG TAGATGAGGT AAGTCTCTTG AGCGAGACTT CTAGGGATGG GAAATTTGTG GTGATTGATA TGAAATGATT TTTCCCTTAT CAGGTTCCAG AGGATCGTGT

TTATGAAGAA TTAAACATAT ATTCAGCTAC TTACAGTGAG TTGGAAGACC CAGGGGAAAT GTCTCCTCCC ATTGATTTAT AAGAATCACG TGTCCAGAAC ACTCTGATTC ACAGCCAAGG ATCCAGAAGG CCAAGGTTTT GTTAAGGGGC TACTGGAAAA ATTTCTATTC TCTCCACAGC CTGCTGGTTT TACATTAGAT TTATTCGCCT GATAAGAATA TTTTGTTTCT GCTGCTTCTG TCCACCTTAA TATGCTCCTT CTATTTGTAG ATATGATAGA CTCCTATTTT TCTTGTTTTA TATTATGACC ACACACATCT CTGCTGGAAA GTCAACATGT AGTAAGCAAG ATTTAACTGT TTGATTATAA CTGTGCAAAT ACAGAAAAAA AGAAGGCTGG CTGAAAGTTG AGTTAAACTT TGACAGTTTG ATAATATTTG GTTCTTAGGG _{ττττττττττ} TTTTAGCATT CTTAATAGTT ACAGTTGGGC ATGATTTGTA CCATCCACCC ATACCCACAC AGTCACAGTC ACACACACAT ATGTATTACT

TACACTATAT ATAACTTCCT ATGCAAATAT TTTACCACCA GTCAATAATA CATTTTTGCC AAGACATGAA GTTTTATAAA GATCTGTATA ATTGCCTGAA TCACCAGCAC ATTCACTGAC ATGATATTAT TTGCAGATTG ACAAGTAGGA AGTGGGGAAC TTTTATTAAG TTACTCGTTG TCTGGGGAGG TAAATAGGTT AAAAACAGGG AAATTATAAG TGCAGAGATT AACATTTCAC AAATGTTTAG TGAAACATTT GTGAAAAAAG AAGACTAAAT TAAGACCTGA GCTGAAATAA AGTGACGTGG AAATGGAAAT AATGGTTATA TCTAAAACAT GTAGAAAAAG AGTAACTGGT AGATTTTGTT AACAAATTAA AGAATAAAGT TAGACAAGCA ACTGGTTGAC TAATACATTA AGCGTTTGAG TCTAAGATGA AAGGAGAACA CTGGTTATGT TGATAGAATG ATAAAAAGGG TCGGGCGCGG AGGCTCACGC CTGTAATCCC AGCCCTTTGG GAGGCCGAGG TGGGCAGATC

ACGAAGTCAG TAGTTTGAGA CCAGCCTGGC CAACATAGTG AAACCCCGTC TGTACTAAAA ATACAAAAAA AAAATTAGCT GGGTGTGGTG GCAGTCACCT GTAGTCCCAG CTACTTGGGA GGATGAGGCA GGAGAATCGC TTGAACCTGG GAGGCGGAGG TTGCAGTGAG CCGAGATCGC ACCAGTGCAC TCCAGCCTTG GTGACAATGG GAGACTCCAT CTCAAAAAAA AAAAAAAAAA AAAAAAGATA AAAAGTCAGA AATCTGAAAA GTGGAGGAAG AGTACAAATA GACCTAAATT AAGTCTCATT TTTTGGCTTT GATTTTGGGG AGACAAAGGG AAATGCAGCC ATAGAGGGCC TGATGACATC CAATACATGA GTTCTGGTAA AGATAAAATT TGATACACGG TTTGGTGTCA TTATAAGAGA AATCATTATT AAATGAAGCA AGTTAACACT CTAAGAGAAT TATTTTGAGA TAGAAGTGAA GCTAAGCTAA ACTTCACATG CCTATAATTG GAGGGAAAAA CTAAGGATAA

AATCTAGCCT AGAAGATACA ATAATTAGTC ATAAACATGC ATTGTGAAAC TGTAGAGAGC AGGTAGCCCA AAATAGAGAA AGATTAGATA AAGAGAAAAT AAGTATCCAT CAGAGACAGT ATCTCTAGGC TTGGGCAAGA GAAAAGTCCA CAGTGATAAG CAACTCCACC TAAGGCATGA ATATGCGGCA GAGAAAACAG CAATAGTGAA TGAATGCAAA AGGTGCTGAG CAAATTCCAC ACATGAGTAT TGTGCATGAG TAAATGAATA AAACATTTGC AAAGACCTTT AGAGAAAGAG AATGGGAGCA TATGTGCGAA ATAAGATAGT TGATTATGAA TAGAAGGTAG TGAAGAAAAG CAAGCTAAGA AAAAATTCTG TTTATAAAAG AAGGAAAAGA TAGTTTATGT TTTTAGCCTA AGTATAAGAG TCCTACAGAT GGACTGAAAA AAATCAGTCT GAGAGTATTA GTCACAATTA ATGAAATAAT TACATTTTAT GTATTGAGGA TGCCAAGATT AAAAGGTGAC AGGTAGATGT

TAATTTCCCT AGATTGTGAA AGTGATCACG ACAATCACAC AACAAATAAT TAAGTGACTT GGTATGCTTT ATTTAATTGT AGGGCCTGAG GTTTTCCATT CTCATTTTTC TAAAATACAA TTTTGTTTCT CCAAATTTGA CAGCAGAATA AAAACCCTAC CCTTTCACTG TGTATCATGC TAAGCTGCAT CTCTACTCTT GATCATCTGT AGGTATTAAT CACATCACTT CCATGGCATG GATGTTCACA TACAGACTCT TAACCCTGGT TTACCAGGAC CTCTAGGAGT GGATCCAATC TATATCTTTA CAGTTGTATA GTATATGATA TCTCTTTTAT TTCACTCAAT TTATATTTTC ATCATTGACT ACATATTTCT TATACACAAC ACACAATTTA TGAATTTTTT CTCAAGATCA TTCTGAGAGT TGCCCCACCC TACCTGCCTT TTATAGTACG CCCACCTCAG GCAGACACAG AGCACAATGC TGGGGTTCTC TTCACACTAT CACTGCCCCA AATTGTCTTT CTAAATTTCA ACTTCAATGT

CATCTTCTCC ATGAAGACCA CTGAATGAAC ACCTTTTCAT CCAGCCTTAA TTTCTTGCTC CATAACTACT CTATCCCACG ATGCAGTATT GTATCATTAA TTATTAGTGT GCTTGTGACC TCCTTATGTA TTCTCAATTA CCTGTATTTG TGCAATAAAT TGGAATAATG TAACTTGATT TCTTATCTGT GTTTGTGTTG GCATGCAAGA TTTAGGTACT TATCAAGATA ATGGGGAATT AAGGCATCAA TAAAATGATG CCAAAGACCA AGAGCAGTTT CTGAAGTCCT CCTTTTCATC AGCTCTTTAT CAAACAGAAC ACTCTATAAA CAACCCATAG CCAGAAAACA GGATGTAGGA ACAATCACCA GCACACTCTA TAAACAACCC ATAGCCAGAA AACAGAATGT AAGGACAATC ACCAGCCATC TTTTGTCAAT AATTGATGGA ATAGAGTTGA AAGGAACTGG AGCATGAGTC ATATTTGACC AGTCAGTCCT CACTCTTATT TACTTGCTAT GTAAACTTGA GAAAGCTTTT TTCTCTTTGT

GAACCTCAGG TTTTACATCT GAAAATGAGA AATTTGGAAC AAAAGATTCC TAACTGGTCT TTCTGTTCCC ATATTCTGTG ATTTTTCAAT ATTTAGGATT TTTGGTAATC ACAATTACTT AGTTTGTGGT TGAGATAGCA ACACGAATCA GAACTATTTG GTGGACATAT TTTCAAAGGA GTAGCTCTCC ACTTTGGGTA AAGAAGTGAT GCNGGTCGTG GTGGCTCACG CCTGTAATCC CAGCACTTTA GGGAGGCCAA GGCGGGTGGA TCACGAGGTC AGGAGATCGA GACCATCCTG GCTAACACGG TGAAACCCCG TCTCTACTAA AAAATACAAA AAATTAGCCA GGCGTGGTGG CGGGCGCCTG TAGTCCCACG TACTCGGGAG GCTGAGGCAG GAGAATGGCA TGAACCAGGG AGGCGGAGCT TGCCGTGAGC CGAGATAGCG CCACTGCAGT CCCTCCTGGG CAAAAGAGCA AGACTGCGTC TCAAAAAAAA AAAAAAAAAA AAAAAAAGAA GTGTGTGGAG

TAGCAGGACA CCTGCAACAA TAATATTTTT CTAAATCCCT CTGAAAAATG CTAATCAAAG GGTTTTTTTC CTAAAAATTG TCTTAGAAAT AAAATTTCCC CTTTGGGAGA CCGAGGCTGG CAGATCACGA GGTCAGGAGA TAGAGACCAC GGTGAAACCC CGTCTCTACT AAAAATACTA AAAATTAGCC GGGGNGTGGT GGTGGGTACA CCTGTAGTCC CAGCTACTTG GAGGCTGAGG CTGGAGAATC ACGTGAAC GCCACGTGCT GCTGGGTCTC AGTCCTCCAC TTCCCGTGTC CTCTGGAAGT TGTCAGGAGC AATGTTGCGC TTGTACGTGT TGGTAATGGG AGTTTCTGCC TTCACCCTTC AGCCTGCGGC ACACACAGGG GCTGCCAGAA GCTGCCGGTT TCGTGGGAGG CATTACAAGC GGGAGTTCAG GCTGGAAGGG GAGCCTGTAG CCCTGAGGTG CCCCCAGGTG CCCTACTGGT TGTGGGCCTC TGTCAGCCCC CGCATCAACC TGACATGGCA TAAAAATGAC

TCTGCTAGGA CGGTCCCAGG AGAAGAAGAG ACACGGATGT GGGCCCAGGA CGGTGCTCTG TGGCTTCTGC CAGCCTTGCA GGAGGACTCT GGCACCTACG TCTGCACTAC TAGAAATGCT TCTTACTGTG ACAAAATGTC CATTGAGCTC AGAGTTTTTG AGAATACAGA TGCTTTCCTG CCGTTCATCT CATACCCGCA AATTTTAACC TTGTCAACCT CTGGGGTATT AGTATGCCCT GACCTGAGTG AATTCACCCG TGACAAAACT GACGTGAAGA TTCAATGGTA CAAGGATTCT CTTCTTTTGG ATAAAGACAA TGAGAAATTT CTAAGTGTGA GGGGGACCAC TCACTTACTC GTACACGATG TGGCCCTGGA AGATGCTGGC TATTACCGCT GTGTCCTGAC ATTTGCCCAT GAAGGCCAGC AATACAACAT CACTAGGAGT ATTGAGCTAC GCATCAAGAA AAAAAAAGAA GAGACCATTC CTGTGATCAT TTCCCCCCTC AAGACCATAT CAGCTTCTCT GGGGTCAAGA CTGACAATCC

CGTGTAAGGT GTTTCTGGGA ACCGGCACAC CCTTAACCAC CATGCTGTGG TGGACGGCCA ATGACACCCA CATAGAGAGC GCCTACCCGG GAGGCCGCGT GACCGAGGGG CCACGCCAGG AATATTCAGA AAATAATGAG AACTACATTG AAGTGCCATT GATTTTTGAT CCTGTCACAA GAGAGGATTT GCACATGGAT TTTAAATGTG TTGTCCATAA TACCCTGAGT TTTCAGACAC TACGCACCAC AGTCAAGGAA GCCTCCTCCA CGTTCTCCTG GGGCATTGTG CTGGCCCCAC TTTCACTGGC CTTCTTGGTT TTGGGGGGAA TATGGATGCA CAGACGGTGC AAACACAGAA CTGGAAAAGC AGATGGTCTG ACTGTGCTAT GGCCTCATCA TCAAGACTTT CAATCCTATC CCAAGTGAAA TAAATGGAAT GAAATAATTC AAACACAAAA AAAAAAAAAA AAAAAAAA GCCGGAGCCG ACTCGGAGCG CGCGGCGCGG CCGGGAGGAG CCGAGCGCGC CGGGCGCGGC

GTGGGGGCGC CGGCTGCCCC GCGCGCCCAG GGAGCGGCAG GAATGTGACA ATCGCGCGCC CGCACCGTAG CACTCCTCGC TCGGCTCCTA GGGCTCTCGC CCTCTGAGCT GAGCCGGGTT CCGCCCGGGC TGGGATCCCA TCACCCTCCA CGGCCGTCCG TCCAGGTAGA CGCACCCTCT GAAGATGGTG ACTCCCTCCT GAGAAGCTGG ACCCCTTGGT AAAAGACAAG GCCTTCTCCA AGAAGAATAT GAAAGTGTTA CTCAGACTTA TTTGTTTCAT AGCTCTACTG ATTTCTTCTC TGGAGGCTGA TAAATGCAAG GAACGTGAAG AAAAAATAAT TTTAGTGTCA TCTGCAAATG AAATTGATGT TCGTCCCTGT CCTCTTAACC CAAATGAACA CAAAGGCACT ATAACTTGGT ATAAAGATGA CAGCAAGACA CCTGTATCTA CAGAACAAGC CTCCAGGATT CATCAACACA AAGAGAAACT TTGGTTTGTT CCTGCTAAGG TGGAGGATTC AGGACATTAC TATTGCGTGG TAAGAAATTC

ATCTTACTGC CTCAGAATTA AAATAAGTGC AAAATTTGTG GAGAATGAGC CTAACTTATG TTATAATGCA CAAGCCATAT TTAAGCAGAA ACTACCCGTT GCAGGAGACG GAGGACTTGT GTGCCCTTAT ATGGAGTTTT TTAAAAATGA AAATAATGAG TTACCTAAAT TACAGTGGTA TAAGGATTGC AAACCTCTAC TTCTTGACAA TATACACTTT AGTGGAGTCA AAGATAGGCT CATCGTGATG AATGTGGCTG AAAAGCATAG AGGGAACTAT ACTTGTCATG CATCCTACAC ATACTTGGGC AAGCAATATC CTATTACCCG GGTAATAGAA TTTATTACTC TAGAGGAAAA CAAACCCACA AGGCCTGTGA TTGTGAGCCC AGCTAATGAG ACAATGGAAG TAGACTTGGG ATCCCAGATA CAATTGATCT GTAATGTCAC CGGCCAGTTG AGTGACATTG CTTACTGGAA GTGGAATGGG TCAGTAATTG ATGAAGATGA CCCAGTGCTA GGGGAAGACT ATTACAGTGT GGAAAATCCT GCAAACAAAA GAAGGAGTAC CCTCATCACA GTGCTTAATA TATCGGAAAT TGAAAGTAGA TTTTATAAAC ATCCATTTAC CTGTTTTGCC AAGAATACAC ATGGTATAGA TGCAGCATAT ATCCAGTTAA TATATCCAGT CACTAATTTC CAGAAGCACA TGATTGGTAT ATGTGTCACG TTGACAGTCA TAATTGTGTG TTCTGTTTTC ATCTATAAAA TCTTCAAGAT TGACATTGTG CTTTGGTACA GGGATTCCTG CTATGATTTT CTCCCAATAA AAGCTTCAGA TGGAAAGACC TATGACGCAT ATATACTGTA TCCAAAGACT GTTGGGGAAG GGTCTACCTC TGACTGTGAT ATTTTTGTGT TTAAAGTCTT GCCTGAGGTC TTGGAAAAAC AGTGTGGATA TAAGCTGTTC ATTTATGGAA GGGATGACTA

CGTTGGGGAA GACATTGTTG AGGTCATTAA TGAAAACGTA AAGAAAAGCA GAAGACTGAT TATCATTTTA GTCAGAGAAA CATCAGGCTT CAGCTGGCTG GGTGGTTCAT CTGAAGAGCA AATAGCCATG TATAATGCTC TTGTTCAGGA TGGAATTAAA GTTGTCCTGC TTGAGCTGGA GAAAATCCAA GACTATGAGA AAATGCCAGA ATCGATTAAA TTCATTAAGC AGAAACATGG GGCTATCCGC TGGTCAGGGG ACTTTACACA GGGACCACAG TCTGCAAAGA CAAGGTTCTG GAAGAATGTC AGGTACCACA TGCCAGTCCA GCGACGGTCA CCTTCATCTA AACACCAGTT ACTGTCACCA GCCACTAAGG AGAAACTGCA AAGAGAGGCT CACGTGCCTC TCGGGTAGCA TGGAGAAGTT GCCAAGAGTT CTTTAGGTGC CTCCTGTCTT ATGGCGTTGC AGGCCAGGTT ATGCCTCATG CTGACTTGCA GAGTTCATGG AATGTAACTA TATCATCCTT TATCCCTGAG GTCACCAGGA

ATCAGG-3'(SEQ ID NO: 12371)

Human Enzyme-related Antisense Polynucleotide

S'-CTT GCT CCT GGG GGC CTC CTG GTC CCT CTG GCT G TT CCC GGC CCT GGB CTG GGG CBG GGG CCG CGT BGG CGC GGC TCG CCB GGB CGG GCB GCG CCB GCB GCB GCB GGC TCB GCB TCC TGG CCB CGG BBT TCC GGT GTG CGG GGC CTG GTG CC CCT GGG CCT CGG GTG CTG CCT GT GCG CTG CCT TCT TCT CCT GG GTC CTC GCC GGG GCC CTT GCT GCC CTG GCT GT GCC CTG GGG GTC TGG GTT CGG CTG T CCC CBG CBG GBC CBG TCC CBT CCB CBG CGT GTG BTG BGT BGC CBT TCT CCT

GCB GCC GBG GGG CGC GGG CGB GCB TCG C TTT GGG CTT TTC TCC TTT GGT T TGB GCG CCB GGB CCG CGC BCB GCB GCB GGG CGC GGG CGB GCB TCG CBG CGG CGG GCB GGG GGGCTCCCGC CGCGBGBGGT TBTGGGCTCC CBGGBCCBCC CGCBCCGCGC GGBCGTTTBC BTTCGCCBCG CBGTGCGCGG CCGBCBTGBC GBBGTTGGGC GCBBTCBGGG TGGCGCCGCB GBBGTGGCCT CCGCGCBGCT GCBGGGBCBC CBTGBBGGGC CBCGCGTGGG GCCGCGCTCG CCGGCCCCCC BCBBTCTCCG BGGCCBGCGC GGTGCCCCCC BGCBGCBBGG CCGGCBGGBC BCBGGCGBGG BGBCBCGCGB GTCGGCGGCC GBGGGTCBTG GTGGGGCTGG GGCTCCGGGG TCTCTGCCCC TCCGTGCTGG TGGGGCTGGG GCTCCGGGG TCTCTGCCCC TCCGTGCCGC GTGGGGCCGC GCTCGCCGGC CCCCCCCTGC CGGGTGGGCT CCCGCCGCGC GCCGGCCTGC

CGGCCCCTCG TGGGTCCTGC TGGCCGGGTC CGGGTCCCGG GGGTGGGGCG CGBGTCGGCG GCCGBGGGTC CCCTCCBCBT CTGCTCTGBC CTGCTGGBCT CTGGBTCTGB BGBTBCGCCB TGTBGGGGCG GGBGTGGGGC CTGCTCTCCC GGCCTCCGBT GBTCTCCCCT GCCTCBGCCC CBGTGGGTBG GBGBBBGGCC BGCBGBBGCB GGBGTGGCTG CBTCTTTCCT GGTGGGGCCT GCTCTCCCGG CCTCCGTGTG TTGCTGGGTG TTTTCCCGTC TCTGGTCTGC CTTCGGGGGT CGT CCGGGGCTGC BGCBBCCTCB TCBGCTCTTG CCTGGBGTGG CTCBGCCTGG GCCTGCBGGG CCBCCBGGBG BBTGGCBGCB BGGBTGGCGB GGGTCCTCBT GGCTGGGGTC BCBGBTCCTC TBGCTBGGCB GGGTGBCCBG BGBGGGC GGG TCC TCB TGG CTG GGG GCC TGG GCC TGC BGG GCC GCT CTT GCC TGG BGT GGC TC GCC CBG BGT CTT CCC TGG T CGCTGCBBTC

TGCTCCGGGG CTGCBGCBBC CTCBTCBGCTC TTGCCTGGBGTG GCTCBGCCTGG GCCTGCBGGG CCBCCBGGBGB BTGGCBGCBBG GBTGGCGBGGG TCCTCBTGGC TGGGGTCBCCT GGBGGBGGGB GBGCBGGGGG TCCTCBTGGC TGGGGTCCCT CTCTCCCGTC CT CGG TTT CCT TTG CGG TC TTG GCC CGG GCT CCG GGT G CCC GCC CGC CCG CCG GCC GCC GC CCC GCC GGG CTG TCC CCG CCC CGC CCC GGC CCG GGG CGC GGG GG CGG CCC TCC CGC CCC TCT GG GCC GGC GCG GGC GTC GG CCG CTC GCG CCT GGG GTT CCC TCT CCT CCC CCT GTG C GCC TGC CTC TTG CTC TTCTGC GTC CGC TGC CTT CTC CC CTC TCC TCG GCC GTT GCC TGT GC TGT CCG TCC TGT CGC CCT TCC GTG GTG C TGT TGT CTC TTC TGC CCT C GGT GTG CTG GTG CTG GTG GTG GTG CCT CTG CCC GTG CTC GCCCTG CCT GGG CTG GCC

TCT TCG GGT GTG GCT TTG GGG CTC TCT TGG TTG CCC TTT CTT CTC GTG GTG CCT CTC CTC CCT GGC TTG GTC GT TGT CTG GGG TGG TGC TCC TCT CCC TTT CCC TGC TGG CCG TTT GT CCT GTT TTC TGT CTT CCT CT TTC CTC CTG TTT CTC CGT TTG GCT TGC TGC TTG CGG GGC TGT CTC C CTT GCC CCT GTG GGC TTT CCC TGG TCC GGT CTT CTC CTT GGG GGT C GCC CTT CTT GGT GGG CTGGCT CGT CTG TCT TTT TCC TTC C TGG GGG TGG CCG TTG TGG GCG GTG TGG TCC GCC T TGC CTC TGC TGG TCT TTC CTCGGTBGBC GCGCTCGBBC TCGGGTGGGC CGGTGGTGBG CGGCGGCGBCB CGCGGBBGGC CCTGCGCGCC GBGBTCBCCTG CBGGGBGBBG TBGGCTTGCB GCBGGBCTCC CBGGBGGGTG BCBGCBGCCB GTBGBGCTBC CTCGTCCTTC BTGGTBCCGT CGGTGTGGTG GCBCGGOCTG TGTGTGBBGG CGBGCTGGGC

CCCGTCTGCT GCTCCTCGTG CCGCCTCGTC CTTCA TGG TA CCGTCGGTGT GGTGGCCTCG GGTGGGCCGG TGGTGGGGCG CGCGCGCTCG CGTGGCTCCG GCTCTTCTTT CCCGGCTCCGT CGGCCCGGGG GCCTTGGTCT CCCTCGTCCT TCBTGGTBCC G BCCGGCGGBG CCGCCBGGGT GGBCTGGGBG TGGGTTTCTC CCCGCCGTTC TCBCCCBCCG CGCTGBGCTC BGCGCCTBBG BCTGCTGTTT CTGGBGCTCC TTGGCBBGCC BCBBBCBGCB GBGBGBBBBT CBTGBGCBBB TBBTCCBTTC TGBBBBBBBG GGBTCBBBBB CCTCCCGTTC CCCGTTCGCC TGGCGCGCGC TGCGGGTTCC TCGTGGGTTT CTCCCCGCCG TTCTCCGGTC TGTTGCCTTT GTGGGCTTCT TGTCTTTTTG GCTGTTCTTT TCCTGCTTGG CGTCTTTTCC TTTCTTTGTG CTCGGTTGTG GGTCCGCTGG TCCTTTGCCC TGTGTGTTTC TGCTGCCCGT TCGCCTGGCG CGCGCTGCGG

GTTCCTCGTG GGTTTCTCCC CGCCGTTCTC CGGTCTGTTG CCTTTGTGGG CTTCTTGTCT TTTTGGCTGT TCTTTTCCTG CTTGGCGTCT TTTCCTTTCT TTGTGCTCGG TTGTGGGTCC GCTGGTCCTT TGCCCTGTGT GTTTCTGCTG GGBGCTGBTB CTGCBGATTT CBGBGGGBBG BBCCCTGBTB CTCBCCBGCT TCBGCTCTGG BGCBCBBGBG BBBGBGCBGC BGGGGGBGBG GBBGBBGCBG CBTCTTCCCB GBGBGGCTGC CTGBGCBBBT GCTGGTTTTC CTTTCCBGTC TTGGGTTTTB TBBCTCCCBG BBGGCBBGBG BGGGGCBBGG CGTTTTCTTC TCTCGCTGGT TTTCCTTTCC TGGCAGTGGG TGGGGGTGGG GGTGGGGTGG CTTCCTTGTT CCTGGGGGTG TCCTCTTGCT CTGGGCTTTT CTCCCCTTTT CCTTCCTGTC TGTTTTCCTG GGGCTCTCCT CTGTCTCTGT GTCCTTGCCC TGGCCCTCTT CCCTCTCCTG TCTCCTGTCC CTGTGTTCCG CCCGTCTTCC

CTCTCCTGAC CTCCTTTTCC TCCGCTGGGT GGGGCCCTGC CTGTTCTCTG CTCCCTGGCT TGGGGTTTCT TCTGTGTGTC TTCTTCCTCT GTTGGCTGGC TTTCTCCTTC TTTTGTCTTC CTGGGTGCCC CTTCTTCCTT TCTTGGGTCC TTGGTGCTTG GGCTGGG GCGTCTTGGG GTGCBGGGCC CBTCCTGCTG CGCCTGGGCG CTGCTGTGCG TCCGTCTGCT GGGGGGCCGG GGTGGCTGGG CCCTGCTTGC CGCACGACCC CGGGCCGACC CGAGGCTCGG GGGGCTGTGT TCTGGCGCTG GTGGGCTTGG GCCCCTCTGG GGGCTGGGTT TCCTGCTGCG CCTGGGCGCT GGCGTCTTGG GGTGCGGGGC CGGGGGGCCG GGGGGCCGCT GTTCGTGGGC CTGGGGGTGC CTGTGGCTGC CGGTTGCCCC GGTTGGTGGC GCCGTCCTGC TGCCGGTCGT TGGCTGGGTC CCCCCGCCCG TTTCCTGGGG TCCGCGTGGG GTGCTCCGGT TCCTCGTGCC GCTGCTGCCT TGTCTTTCCG

GCCGTGGCGG CGTGGTGGTC CGCCCCCCCT GGCCTTCTGC TCGGGGTCTG GCTGGTTGCC GGTGCCCTTG GCGGCGGTCT TCTTCCTGGT GGCTCTGGGC CCGGCCGGTC TCGGGCGTCT CGTGTTCGCT CTTGTGCTGT TCCGGCCGCT CCTTCCTCTT CCGCCGCCGC CGCTCCCCGC CCGCTCGTCG CCCTGGCCCG GCCTCCTCCT GGCCGCTGTC TCGGGCGGCG GCCTTGGCGC TCCGTTTGGG GCTGCCTCTG GCGCTTCCGG CCCTCGGCCT GGGCGCTCTC TTCCGCCTGT GCTGGTGGCC CTCGTGGGCC CCTCCTGGCC TCCGGTGTCC TGTGGTCCCC CGGCTGGTGG CCGGGCCGGT TGGGCGGGCG TGGGCGCCGG CGGGTCCTCC GGGCTGCCCT TCTCCGCCGG GGGTCCCGCG CTCCTGCTGT TCCCTGGGCT CTTCTGCCTC TCTCCTGGGT GGGTGCTGGG TGCCGGGGTC TCCGGGCTTG CCCCGCGCTG CTGGGCGTTC TGCGGTCTTG GGGTTGTCTG TGGCCCCGCT

CGTGTCGCCC TCCGTCGCCC GTCGCCGGCC TCGTCCCCTC CTGGGTGCGC GGCGGGCTGG TCCTGGCGTT TTGCTCCTTC CTGGGCGTCT TGGGGTGCBG GGCCCBTCCT GCTGCGCCTG GGCGCTGCTG TGCGTCCGTC TGCTGGGGGG CCGGGGTGGC TGGGCCCTGC TTGCCGCACG ACCCCGGGCC GACCCGAGGC TCGGGGGGCT GTGTTCTGGC GCTGGTGGGC TTGGGCCCCT CTGGGGGCTG GGTTTCCTGC TGCGCCTGGG CGCTGGCGTC TTGGGGTGCG GGGCCGGGGG GCCGGGGGGC CGCTGTTCGT GGGCCTGGGG GTGCCTGTGG CTGCCGGTTG CCCCGGTTGG TGGCGCCGTC CTGCTGCCGG TCGTTGGCTG GGTCCCCCCG CCCGTTTCCT GGGGTCCGCG TGGGGTGCTC CGGTTCCTCG TGCCGCTGCT GCCTTGTCTT TCCGGCCGTG GCGGCGTGGT GGTCCGCCCC CCCTGGCCTT CTGCTCGGGG TCTGGCTGGT TGCCGGTGCC CTTGGCGGCG

GTCTTCTTCC TGGTGGCTCT GGGCCCGGCC GGTCTCGGGC GTCTCGTGTT CGCTCTTGTG CTGTTCCGGC CGCTCCTTCC TCTTCCGCCG CCGCCGCTCC CCGCCCGCTC GTCGCCCTGG CCCGGCCTCC TCCTGGCCGC TGTCTCGGGC GGCGGCCTTG GCGCTCCGTT TGGGGCTGCC TCTGGCGCTT CCGGCCCTCG GCCTGGGCGC TCTCTTCCGC CTGTGCTGGT GGCCCTCGTG GGCCCCTCCT GGCCTCCGGT GTCCTGTGGT CCCCCGGCTG GTGGCCGGGC CGGTTGGGCG GGCGTGGGCG CCGGCGGGTC CTCCGGGCTG CCCTTCTCCG CCGGGGGTCC CGCGCTCCTG CTGTTCCCTG GGCTCTTCTG CCTCTCTCCT GGGTGGGTGC TGGGTGCCGG GGTCTCCGGG CTTGCCCCGC GCTGCTGGGC GTTCTGCGGT CTTGGGGTTG TCTGTGGCCC CGCTCGTGTC GCCCTCCGTC GCCCGTCGCC GGCCTCGTCC CCTCCTGGGT GCGCGGCGGG CTGGTCCTGG CGTTTTGCTC

CTTCCTGG CTGCCCCBGT TTTTGBTCCT CBCBTGCCGT GGGGBGGBCB BTGGCTGCCT CCCCGGGGTT TCTGCTGCTT GCTGCTTCTT TCCCGTCTCC CTTCTTTCCC GTCTCCTTTT TGCCTCTTTG GGTTCCTGTT GTTTCTGGCC TGCTTGGTGG CGGCTTGTGC GTTTCCTCTC TCTTCTCTTG GGTCTCCGCT TCTCGTCCTG CCTTTTCCTG TCTCTGTCGC GCCGTTCCTC CTCCGGCGTC CTCCTGCCCT GTGCTGTTTG CCTCGGGTGG TGCGGGTCCC GGTGCTCCCC CGGCGGGCCG GCTGGTTGCC TGGGCCTGTC TGGTGGGGTG TGGGGCCGCT GGGTTGGGGG TGTGGTGGGC TCTTCTGTGG CCTGTGGGGC TGTTGGTGTC TCTGTGGGCG TGTGCTGGGT CTTGGGGCTT CCTCCCTTGT GCTGGGTGCG GCCTCCCCGC CCCCCTTCTG GGCCGGTGGC CTGGCTCCTT GTGGGCGCTT CTGGCTCTTG CCCTGTCCTT CTTCGCCTCG TGGCTGCTGG GCTGC

GCCGCCGCCG CCAAGATGGC GGACCTGGAG GCGGTGCTGG CCGACGTGAG CTACCTGATG GCCATGGAGA AGAGCAAGGC CACGCCGGCC GCGCGCGCCA GCAAGAAGAT ACTGCTGCCC GAGCCCAGCA TCCGCAGTGT CATGCAGAAG TACCTGGAGG ACCGGGGCGA GGTGACCTTT GAGAAGATCT TTTCCCAGAA GCTGGGGTAC CTGCTCTTCC GAGACTTCTG CCTGAACCAC CTGGAGGAGG CCAGGCCCTT GGTGGAATTC TATGAGGAGA TCAAGAAGTA CGAGAAGCTG GAGACGGAGG AGGAGCGTGT GGCCCGCAGC CGGGAGATCT TCGACTCATA CATCATGAAG GAGCTGCTGG CCTGCTCGCA TCCCTTCTCG AAGAGTGCCA CTGAGCATGT CCAAGGCCAC CTGGGGAAGA AGCAGGTGCC TCCGGATCTC TTCCAGCCAT ACATCGAAGA GATTTGTCAA AACCTCCGAG GGGACGTGTT CCAGAAATTC ATTGAGAGCG ATAAGTTCAC

ACGGTTTTGC CAGTGGAAGA ATGTGGAGCT CAACATCCAC CTGACCATGA ATGACTTCAG CGTGCATCGC ATCATTGGGC GCGGGGGCTT TGGCGAGGTC TATGGGTGCC GGAAGGCTGA CACAGGCAAG ATGTACGCCA TGAAGTGCCT GGACAAAAAG CGCATCAAGA TGAAGCAGGG GGAGACCCTG GCCCTGAACG AGCGCATCAT GCTCTCGCTC GTCAGCACTG GGGACTGCCC ATTCATTGTC TGCATGTCAT ACGCGTTCCA CACGCCAGAC AAGCTCAGCT TCATCCTGGA CCTCATGAAC GGTGGGGACC TGCACTACCA CCTCTCCCAG CACGGGGTCT TCTCAGAGGC TGACATGCGC TTCTATGCGG CCGAGATCAT CCTGGGCCTG GAGCACATGC ACAACCGCTT CGTGGTCTAC CGGGACCTGA AGCCAGCCAA CATCCTTCTG GACGAGCATG GCCACGTGCG GATCTCGGAC CTGGGCCTGG CCTGTGACTT CTCCAAGAAG AAGCCCCATG CCAGCGTGGG

CACCCACGGG TACATGGCTC CGGAGGTCCT GCAGAAGGGC GTGGCCTACG ACAGCAGTGC CGACTGGTTC TCTCTGGGGT GCATGCTCTT CAAGTTGCTG CGGGGGCACA GCCCCTTCCG GCAGCACAAG ACCAAAGACA AGCATGAGAT CGACCGCATG ACGCTGACGA TGGCCGTGGA GCTGCCCGAC TCCTTCTCCC CTGAACTACG CTCCCTGCTG GAGGGGTTGC TGCAGAGGGA TGTCAACCGG AGATTGGGCT GCCTGGGCCG AGGGGCTCAG GAGGTGAAAG AGAGCCCCTT TTTCCGCTCC CTGGACTGGC AGATGGTCTT CTTGCAGAAG TACCCTCCCC CGCTGATCCC CCCACGAGGG GAGGTGAACG CGGCCGACGC CTTCGACATT GGCTCCTTCG ATGAGGAGGA CACAAAAGGA ATCAAGTTAC TGGACAGTGA TCAGGAGCTC TACCGCAACT TCCCCCTCAC CATCTCGGAG CGGTGGCAGC AGGAGGTGGC AGAGACTGTC TTCGACACCA TCAACGCTGA GACAGACCGG

CTGGAGGCTC GCAAGAAAGC CAAGAACAAG CAGCTGGGCC ATGAGGAAGA CTACGCCCTG GGCAAGGACT GCATCATGCA TGGCTACATG TCCAAGATGG GCAACCCCTT CCTGACCCAG TGGCAGCGGC GGTACTTCTA CCTGTTCCCC AACCGCCTCG AGTGGCGGGG CGAGGGCGAG GCCCCGCAGA GCCTGCTGAC CATGGAGGAG ATCCAGTCGG TGGAGGAGAC GCAGATCAAG GAGCGCAAGT GCCTGCTCCT CAAGATCCGC GGTGGGAAAC AGTTCATTTT GCAGTGCGAT AGCGACCCTG AGCTGGTGCA GTGGAAGAAG GAGCTGCGCG ACGCCTACCG CGAGGCCCAG CAGCTGGTGC AGCGGGTGCC CAAGATGAAG AACAAGCCGC GCTCGCCCGT GGTGGAGCTG AGCAAGGTGC CGCTGGTCCA GCGCGGCAGT GCCAACGGCC TCTGACCCGC CCACCCGCCT CCAGGAAGCT ACCTGGAGGA GGTGAGTCTT AGCGGATGAG

TAGGAGTTGT CCACGGAGGA AGGTACACAG AAGGGCTTCC AGGCCCAGGA AACAGCAGAG GCACAGAAGT GAGAATGGGT GGGTGAGTTG GTGGGGAAAC TCCAGGTGCA GAGGATGGTA GCGAAACAAA CTGGAGCATT AAGGTCCAAG TCCTCCAAGA TCTTGACTTG CAGATTAAGG AGTTTGTTCA CCTAATCTGC TTTGGGCAGA GTGTGGTGAG TCCTAGAGAC CCCTCTAGGT CTCTCCTCTC AGTAGCCCCA GAAGGCCTGG AGAGCTGCTT CTGGGTGCCA AGCAGGCAGT GACTCCATCA GATCTAGATT TGGGAAAAGC ATCCCTGGTC AGGGCCTGCA TCAGGGCAGT GGCTGGCCAT GAGGACCCTG AGAAGTAGAC AGATTCACGG AGATTCTCAG GAGGCCAGAC AGGAGACTAT GGTGACAAAT TAGATTAGAG AAGGGGAGAG AATGAAGGAG CAGTTGGGGT AAAAGAAAAC TGAGGCTGAC ATGGGTATAT GGGTGGCGAG

TGACTCACCA CCCACTGAGA GGAGAACCTC ACAAGCTCTG ACATGCTCTG GTTCCAGGTT CTGTTGGGGC TGATCCAAGA TGGTAGCCTA GAGGTGCACA GAGATGGGGG CCTTGCTTTG CAAAAGGATG CTGGCTGCTG GCCCACAGCA TGGTAATGAG ATTTGAGCTT TATGTGCCCA GGGCTGGGAG GAGGGTCCTG TCACTTTGAA AGCAAAGAGA GGCTCTAGAG AGGGGCATGT TGAGATAGGA ATGCTGCCTT GAGACACCTG GCTTTCCCCA CTCTGGGTGG CTCTCAGCAG GGTGGGTTTC CCCTGCCAGG CAGCACTGAA CCTCTGTGCG CTTCCGGCTG GGAGAGTTTT TACCGTAACT ACATGTGGAA CCATCCTGAA GGAACATCTG GATGGGATGG GGTACAGGGA AGGGAGCTGC CAAGAGTGCT GGCCAGGGAC CTGGGTCTAT GAGCTGGTTG GGGGGTGGGG TTGGGTGCAG GGTACTTGAT CCTGAGTGGG CCTTCTGCGG CCAGGATTGG TTCTAGAGTA GGAGGGGTGG GATCGGGGAT GGGGGAAGCC TGTAACTGCG CTGCAGTTGT CAGGTCCCAG GTTCTGGGTG ACCTACTAAG GATTCTGGGT CCAGTGTGGG TCCCAGGTTA GACGTCCTAG TCCTGAGTCC GTGTCCACAG TTCTGGGTGT TGAGTCTAGG ACAGTGATCT GGAGTTGACA GTCCAATCTA GGTCTGAGTC CTGACCCCAA GTCTAGAGTT CAGGGTCATG GTAGTAGCCT AGGGTCAGAA TCAAGGTTGG GGTCAGTAAC CAGGATGGGA TCGAGGTCAT GGTCCAAAAT CTGGATCTGG GGACCTGTTG GGGGTCTGAG GTGAGTGTCG CAGTCTGGGT ATGGCGTTGG AGACCCAGGG CTGTGATCTG AGGTCATGGT TAGAGTCTCA GGTGGTGGGC CAAGGTTTGA GTCTGGGGTC

CTGTTTGGAG TCTGGTGTCA GGTCGTGGAC TGCGTCCAAG GTCAGGGAGT CCGGGGTTAT AGCCAGGGTC TGAGATGAAA GTCCCAGATG GTGTTCAGAG GTCTGAATCT GTGTCTTGGT GAGCGTCCAG GTTCCCTGTG ATCACGTTTG GTGTCAGGGC TGCGGCCCGA CTGGGGAGCC TGGGATCCAG AGATGTGACC CGAGGTTGTG GTCAGAGAAT GGGTCTCGGG TCGTCTTCGT GCCGGGTCCC TGTCGTGTTC CAGGCCCGGG TCTCCGTCCA GCATCGAGGG CCGAGGTCAC GGCCAGGGTC TGAGCCCGCG GTCGCAGGTC TGGTTCGGGG TCAGATTCCG CGCGGCCTCC AGGGGGCGCC GTCGCCGCCC GGCTCGGCCC CTCGCGGGCT CGCTGGCGTT GTGCGCGGCA GGCGGGGCCG GAGGCGGCGG CGGCTCCGGG GGCGCGGGCC GGGCGGCGGC GGCGGCGGCG CCCCGACTGC AGTCCCGGCG GGAGCGGAGC GCGAAGCGCG GGGCCGGGCC

CGGAGCCGGC GCCATGGGGC GGCGCCGCCT GTGAGCGGCG GCGAGCGGAG CCGCGGGCGC CGAGCAGGGC CAGGCGGGAG CGTCGGCGCC CGAGGCCGAG CGAGCCGCGG CCGGGCCGGG CCGAGCGCCG AGCGAGCAGG AGCGGCGGCG GCGGCGGCGG CGGCGGGAGG AGGCAGCGCC GCCGCCAAGA TGGCGGACCT GGAGGCGGTG CTGGCCGACG TGAGCTACCT GATGGCCATG GAGAAGAGCA AGGCCACGCC GGCCGCGCGC GCCAGCAAGA AGATACTGCT GCCCGAGCCC AGGTGAGGAG AAGCT TCCCAGTTAA TACATAATCA ATATGCAATT TATTAATACA TCTCTCCATG TCCACTCCCC CTGTATCTTG CCATTCTTGA CCTGCATTTC CATCCTCCTT ACCTTCCCTA GAOGCCAACT CATTTTCTTT GAAAAACCTG GCATTTCCCA GAAAAAAAAG TGAAGGGCTG GGAGCTGTCC GTTGTCCTGA TTTGCTCCCT

CTGCCCTTGC TTCCAAATGT GGTTGGAAAG AAGCACTATT GAAAAATCCC TAAACGCACC CCTGCAGGGT TGGCTCTACC CTGTAGCCAT GGACACATGC TGTTGATACC ACCTGCCTCA TGAGTCTCAC ATAATTTGCC CTTTCACACT ATCTACCCCA TCAGCCTTAC CAAAACCATA CCTGCATCCT GGGCAGCATC TGCCCTTCAA GAGACTAAGG AATCTCCTTG CAACCAAGAA TGACTAGACC AATGAGACAC CCTTTAAGGC CCCAGCACAA TATAGAAATC CCACAATATG GTAATCCCAG TAAGGAGCTA TCAAGCCATT GCAGGACCAT CTAGAATACA ACTAGAGTAT AGTTCCTTTC AATCCAGGAA CTATACTCTA ACAGCTTGGC TCACAGGAAC CAGAAGTGAA GATGATGAGG ATCAGGGCTG AGCCTGTGAG CACCAGCTCC ACCACTGACA CCAACCACAG ATTAAACAAG CATCTTGTGG ACCCCTGGGA TGGAAAGAAT AGTTGTTGCC TTATCAACCT CCCCCACAGC

CCACACAGAA AAGATAAAAT CATCATGGCT ACAGTGTTAC AGAAGATGAT GACCCAAGGA GTAGGCCTGC CTGAGTGAAT GCTGAGAGTG ATAATGGGAG CAGTAGCATC TCAGAGACTA CAGCAGAAAC CATCCACATA AAGAGCTTTG CCCAAACTTA TGATAAAGGG CACCCTCAGA GACTCTCCCT ACTTTAATAT TAGCCCATTG CAGAAATGGT GAGTGGAAAG AGAAATCTTA GGAAGAACCC CTTAAAAAAG CAAAATGCTT TTTAGGTTTG TGCTGAAGAG CCTGGAAAAG AAATAAGGAC ACACACGCTG AGAAATCTTC CTCCTGCCCC AACACTGGGA TAATCTCCAA GGATCTCTCC ATATCTCATT CTCCTGGATA CACTGTCCAC TCAGAAATAT TGTGCAGAGT GCAGTAATTC AAAAGTGAGC TATTGTGTTA GGAGTGAAGG CAAGAGTATC GTAAAATAAA TCAAATTTGA AATGAATTCT CTTAAATTGC TTTATAGATG TTTAATGTAA

GCCAGCAGCT ATTAAACGAT AAACCTTAAA TTCGAGAAAA ACTTGGTCAT TCAGAAACTA TAGAAACAGG CAGGACTTAT TGCGAGGGCA AACACAGAGT GAGCTCCAGC CTGCTTCAGG AAAATCTGCC AGTGCCATGA AGGATGTACT CTGTCTGCTC CACTGCACTA CTGCTCAGTA TGAGCCCATG CCATCAGCTG TCCCTGACCC ACAGGAGTTC TTTAGAAGAG ACTGGTCAAC AAAAGTTTCT AGGGTGTTTT ATACCTGCCA ACTCGAGGGT TAAAACAAGT TGCATAGAAA TGCTCAATCA AGAAAGACAC AGTCATTACT CAGAGAATAA TAAACAGCCT GGCAGCACAT GAATGAATAG AAAAAAGATG TTACATGCAA AGCATGAAAT AACCAAATTC CATAACAGAT GTTAATCTGT AATGTGTTTA GGAGAATTTA GAGGAAGTAT AAGATTTATT CTTTCATCAA AAAAATTATA GCCAATGAGG ATATATCTAT CAATTATCCA TCAAGTGGTG ATATGGCAGC ACAAGGTAAA

ACACAAAGGA ATAAAACCAA CGTTTATTAA GAACCAATCA TGTGGCATTT CACATTGAGC ATCATATTTA ATTCTGAAAA AAATCCTTGT ACTGTATCAT TCTTCATATT TTATGGATGC AGTAACTAAG GCTGAGAACT TTAAAATTTT TCCTAAGTTC AGACACATAG CTAAGTGGCA GAACCAAGAT TCAAACTCAC CCCATCTAAC TGCAGAGCAA ACTGCATGCC TTAAATGTCA AAGTGAATAC TAGCACAGTT AATACAATGT TTGGAAACTC AGAGAAGGAA TGATCCCTCT GCATTATAGT TACTAAGGAA TCATTGCCAT TATTTAAATG CCAGTGCTTC TACATCAGGC CCAAATTTTC TGTCCTACTA ACTGTGAATC AAGACTTGAT TCAACCTCTA CTTGAGTATC TGCCGCAATG AGAAATCACT TACCTCCACT AACCACACAT TTATTTTATA ACAACAGATT GTTAGTAAGT CCTTTCTTAT ACATACTCAA CAGCTGCTTC CCAAGATGCT GTAGGATTAT GTCTAGAGTC

AAACTAGCCA GAAGCAATGT CCAAAATACA CCATAACACT GTGCAGCAAA GGTCCTACTA CCACTTGTTT GGCCCAAACA TTCTAGGCAG CACTGGATAT CTGAATCATC AATTATTTCC ACAAACACTG ACCCCTCTAC CAGTCACCCT CACTAGAAGA ATTAATTCCA CATGATAATA GCTCCCTCAT GTTACTCCCT TCTAAGTCAA ATTGTACACC CCTTTATCTG ATTAACAGAG TCTAAGTCAC ATGACCTAAA TGCAAGAGAA CTGGGAATGG ACGTTTGTGG ATTCTACCTT AGTAAGGCAA AGTTATCATT GGGAATTCCT CTAATACAGG AAGGGTGTTC CAGAGACATT AAGGAGCCAT ATAAATGGAA AATGTCCACT ACAATCCATC ACTTGGTTGC CCCACATCAA CATTCATTCT TTTGCCACAC TTAAAGTTTC CAAGAACAAA AATTATCCCA CTGAACATAA TCTTTACTAT CTTTTATATA AAGGAAAATT AGACTTGACT CAGCAGAACT GAAATAACCC AGCTCTAACA

GTTACTGCTT TTAACTTCAA GTACTGTGTC TCTAGGTGAT ACCTGCTCCA ACAATAGTTT GGTCACATTT TCAATTTGAT ATTCTCTAGT CTCCCAACTT GATAACTGTA CCCTAAACCA TAAAGTTCAC TACCAACATG CTATATATAA AATAACCAAA GGGGGAAGAA GAAAGAGAAA AAGGAAATCT CTTAAAATAC ACAGGTATAC ATATGACAAA GCAAAGAAGG AAATGTGAGC AGATAGTGCA GTCCTCGTTT CTGAAATTGG TCCCCTGACT GGGGCTATAC CTATTCCATT TCCTCACCCT CAGCCAGGCA GGTGGAGCAA AAACTTAAGT CTTGGTGGAT CTGAATCTTG ATGCTGTGGA GCTGTCTTAC TAGCCCCAGA CTACCTGCCT CTCAATTTCT AATTATATCA GTGAAAGCAA ACAGCTTTGA TTTGTTTAAG CCTCTGATTT TTTGGTCTAA CTGATGTAAG ACCACAAGGA CAAGAGTTCT CCAGCTCCGG ATTCTCTTCT GTTCTGTTAA TGGTGAAATG CCCGAGAGAA

GAGTTGCCAA CTTTGGCAAA TAAAAAATAC AGGATTCCAG TTAAATTCAA ATTTAGATAA ACAACAATTT TTTAGTATTA GTGTGTCCCA TTCAATATTT GGACATACTT AACTAAAAAA TGATTTGTTG TTCATCTGAA ATACAAATTT AACTGGGCAT TCTGAATATT CTCTGGCAAC CCCCGAGAGA GTGAAGAAAG TGGTACAAGG ACACTTAAGA AGACCAGATT TGAAAAGACA TTACGGATGT GTTTAAATGT CTTATTCTAG AGAGAGTTAG AGCTGTAGGT AGAACTTGGG AAATTAAGTT AAAAGCAGAC ACAGAGACCT GGCCAATATA TACTAAGGAG TGGATCACTC TGGTCACAAG CCCAACCTGA GACCAAGGGC ATAGTGAGAT GATTTGGGAA AGGCACTTAT ACACTACTCA TCCCCGTCTT TGAACTAAAT GCCTTATAAA TCTCCAAGAG AAATGACAGT CCACCATGTG GACTGCTTTC TGTAAGTCCA GGGAAAATAA AAGCTATGTG CTTGAAACCC ACTTCTGATA

TTATAAGGTG TGTGATCTTT GTCATGTTAA TGGGTCTGAG TATCAATTCT ACAATTGTAA AGTGACAGTA ATGGTGTGTC CCCAGGTTGT TGTGGAAAGC TTGATTCTTA ATGCAACAGT AGGAAACCCC AGCCTCTCTG GAGCAAACAC CCTTCTACAT CTTTACTTCC CCTGCACATT GGCAGGACTC TATTCCTCTA TTTCTCTCTA GTGCTAGAGC AGAAAGGGAC CTTGATTTGA TATCAGGAAA ATCTATTTCT GAACCATAAG CTATGATAGC TGATTTAAAA AATTGACTAT CATGACATGA TAATGATCAT AATGGTAATA CATATTGATA GGGTTGCCGT GAAAGTAATA ATATATCTAA GAGTTGTGAC AATATATGAT ACGCCTAGAC TCTCAGAAAA TGCTAATTCC AATCCCAATT GCTCTTTGCA TAAAGTTCTG TCCTAGGGTC TGTTCTTTTC CCACATCTAC CCTCCTTGGA TCTCTCTTCT GTCTTTTTCA TGTGGTTCAG AGGAGGAGAG AGATCCAGGT CAATGTTTTT

CAAATTACAA GGAATTATCA TTTAAATGGG GAAGAAGCTC AAGTTTTGAC GTGTAGTGGA ATTGGAGTGG AGTGGAGTGG AATGGAAACT AACAGGAAGA CACTGCACAT GGTTAAGATA AAGATTGTTT CCTGAAACCT TTAATTTGTG CTTACATACT CACACATACA TATGTGCATG CACTGGGACT CTGCAATATG CATTTCTGAC TATGGAACAT AGCCATAAAA GTCTTTGCAC TGAACGTTCA GTGGGCCTTT CACAAGCTGC CCTAATTGGG AAAGAAAAAC ATGGTCCCTC CATTTCCTGC CCCCAACTCC AGAAAAGTCA CCATAGTTGA GGGTACATCT GAGAAGCCAG CACTTGGGAG TTCAGGGCTC AAGTTCCTTT CTAGAAAAAC ACTGGGTGAT TCTAGGGGAA CTTCCGATCA GAAACAGCCA ATTCAGAGTG AGAGAAGAAA ACGTGACCAT GCAGTTCCTG TGGTTACCAG CCTTGCCCCT CTCTTGCCTT CTGGGAGTTA TAAAACCCAA GACTGGAAAG

GAAAACCAGC ATTTGCTCAG GCAGCCTCTC TGGGAAGATG CTGCTTCTTC CTCTCCCCCT GCTGCTCTTT CTCTTGTGCT CCAGAGCTGA AGCTGGTGAG TATCAGGGTT CTTCCCTCTG AAATCTGCAG TATCAGCTCC TGAAACAAAG ATGTTTAGTC TGAAATAGCT GACTCCTAAA CAGGGTTCCA AGATCTCTCT TCAAGAGTCC CACAGAGGAA ATTTCCACTT GGGATGTGTG CCACCCCACC CCCACCCCCA CCCACTGCCA TTCTCTACAG CCTAGGACAC CCCCAGGAAC AAGGAATTTC ACCTCAATTG TAGAAAAGCC CAGAGCAAGT GGAAGGAAAA GGGGTATCCC CAGGAAAACA GACATGTCCT CTTAATCTTC TGAGCATCAG GGCTACCCAT TACTTTGTGA CTTTCTCACT CTGTGACCAT GCTCAAGAGC TATGGAGAAA TCTAAAACAG GAACCTGGAC AGTGGGTCCT ACACAGAGAC AGAGGAGAGT GGGCCAGGGC AAGGTGGGAG TGGGAGAAGT

CTGAGATGAA AACATCAGAA TGGAGCAGAG GCAAGAATGA GATTTCACCT GGGAGGTTAT GGGTGGGGAA AGATACGAAA TACAGGAGAC AGGAGAGGGA AGATGGGCGG AACACAGGGT GAGAATGAGA TTCCAGGGAA GCCTAGCTCA GCTTTAACCC AATTTGTCCA TTCATTGGAG AGAGTATCTA TGGCCGTGTT CAAACCCTGG GGTGCTCTGT TCCAGGGGAG ATCATCGGGG GCACAGAATG CAAGCCACAT TCCCGCCCCT ACATGGCCTA CCTGGAAATT GTAACTTCCA ACGGTCCCTC AAAATTTTGT GGTGGTTTCC TTATAAGACG GAACTTTGTG CTGACGGCTG CTCATTGTGC AGGAAGGTGA GACAACAGGG TCTATTTATC TCCAAATGGG AGATGAACAA CCAGAGTAGC ATCCAGGAAT ACACCTGCAC TGGGGACTGA AGAGGGGGTC CTGGGTCTTG TCAACTTTCA GGAGAGGGAA GACTTTGGGC TGAAAGACTT TAGTCTGTGT TTGAATAGTT

CCTTGAGCCT CAGTCACTGA GCTAAGCTCC CTTCGGAGGA AAAGGAGGTC CTGTCCGAAG GTCCCTCTTG TTGCAGTAGC ACCCCTCACC CCTACCCAAC TCAAGACACA CGGCTCACTT TTCAGGGCCC CACCCAGTCT CAGGGCCACT TCCTCTATGG CCTTTTCAAG AACACTGGCT CTAGTTCTCA GGGTCCTGAA CCCATCATTT TATGGGAGCA GAGAACAGGT CTACATAAGA CCCCCACTTT CCCGTTTTAA CTGATATCTC CTGCTTCAGG GGCTGGCCCT CATGCAGGGT TCCCTGAATT AGGAAGTGTG AACCCTGTCC CCTGAGTCCT CCCTGGGCTG TTCAGTCCCC AGCAATTCCA GGGGTCGTAG AAATTGTGTC TGTTTCCTGA GAAAGCTCTT TCATGAGTTA AGCCTGAGCC CTCAAATGCC ACAAGTGGCC CATGAAAAGG GAGATGGGTA GAGTCCGGCN ACCCAGTGAC AGAGTTTAGT CCTCTTTTCT CAGAATGAGC TCACCTCAGA AGAAACCCCA AGCCATCACT

GTCGCCTCCT TTTCCTTCCT TCTTCCTCAC AGCAGGTCTA TAACAGTCAC CCTTGGAGCC CATAACATAA CAGAGGAAGA AGACACATGG CAGAAGCTTG AGGTTATAAA GCAATTCCGT CATCCAAAAT ATAACACTTC TACTCTTCAC CACGATATCA TGTTACTAAA GGTGACAACA CCTCTCTTCT CCCTTTCCAC TTCCCATTCT CCTAAGCTTC TCCTTCAGGT CCTCATTGCC CTGAATTTTT CTTAGGACTT GGCTATAACA TGAAGCTACT CACCCTGTCC CTCCCTGATC ACCTCCAACT GTCCAGAGCC CATTTCGAGG ACTGACAGTC CTTCATTCCC TTCACAGTTG AAGGAGAAAG CCAGCCTGAC CCTGGCTGTG GGGACACTCC CCTTCCCATC ACAATTCAAC TTTGTCCCAC CTGGGAGAAT GTGCCGGGTG GCTGGCTGGG GAAGAACAGG TGTGTTGAAG CCGGGCTCAG ACACTCTGCA AGAGGTGAAG CTGAGACTCA TGGATCCCCA GGCCTGCAGC

CACTTCAGAG ACTTTGACCA CAATCTTCAG CTGTGTGTGG GCAATCCCAG GAAGACAAAA TCTGCATTTA AGGTGATCCT CCAACTAGGT TTCCTCTCCA AAACTCACTG TTCAGGGACC TGAATGCTCT TAGAAGGAGA TGGGGTCAGC AGGTTGTCAG TCAGGTGACA GGGTGAGCAT CACAGGAATT GCTGTCCTCC CGTGGTCCAA GACAGCCTCT GACCATCCAT TCCAGTCTAC TGCACTGGGG GCATGGGGTG ACTGTGGAGA ATGTGGATGA CGGTCCCAAG AAAGGAAGAA GGGGCATCAG AACTAGATGT ATAAGTGAGG AGCTCCACCT CCTGGGTCTG ACTTTAGGTC TCACTGTGAC TCCAAGCTGG CTGGCAGACA GGAGTGGAGG ACTTCCCGGG CTCACCTTCT TCTCTCTCTC CTCCCCCTAC AGGGAGACTC TGGGGGCCCT CTTCTGTGTG CTGGGGTGGC CCAGGGCATC GTATCCTATG GACGGTCGGA TGCAAAGCCC CCTGCTGTCT TCACCCGAAT

CTCCCATTAC CGGCCCTGGA TCAACCAGAT CCTGCAGGCA AATTAATCCT GGATCCTGAG CCAGCCTGAA GGGAAGCTGG AACTGGACCT TAGCAGCAAA GTGTGTGCAA CTCATTCTGG TTCTACCCTT GGTTCCCTCA GCCACAACCC TAAGCCTCCA AGAGGTCTCC TACAGGTAAC AGAACTTTCA ATAAACTTCA GTGAAGACAC AGCTTCTAGT CGTGAGTGTG TGTCCCTCTC TGCTGCTCTC TTCTCCTGCA CATGTGACCT GATTCCCAGC CCAAGCACCA AGGA CACCGCTCCT GTCAGCCAAC AAATATCCAT TGAGCGACAC CTGTGTCCCA GGTGCTGCTC TGGGCCCTGG GAGAAGTGCA TCAGTGGGCT TGGTAGTAGA GGGTAGGGAT GGAGTGAAGG GTAGGCAGGA AGAATGTCCC CAGGCTGGTA GGAGGTGGGG TGGGGGGTTT CAGTCTCAAA ACTCCCATGA AAACCAGAGA GAAGTTTCAG AACTCCACCC AAGAGGCTGG GTTTCTAGGG

CCCAGAGCTG CCCTCCCCCA CCCTAGAATG GGCTATAAAA GTCCCTTCCC AGCTACGTCC AGAGAAGAGC TGGAGGAAGT GAGAGGTCGG CTGGGGGTCC TCAAAGTGAG AGGGGAGCAG AGGATCCTCC CGTGCAGGCT GTGGATGTCA CTCACTTCCC AGCTGGTGAA GCCTCGCTGC AGAGATGCAT CTGCTCCCAG CCCTGGCAGG GGTCCTGGCC ACACTCGTCC TCGCCCAGCC CTGTGAGGGC ACTGACCCAG GTAATAGTCC CCTAGACAGG CAAGGAGGAG GGAGGGGAAA TGGAAGGGGA AGCACTTGGG TCTTGGAGGG GGTCTTGTGG CTTGCTGAAC CCTGAGTCCC CATCTCTTTG AACAGCCTCC CCTGGGGCAG TGGAGACCTC GGTCCTGCGA GACTGCATAG CAGAGGCCAA GTTGCTGGTG GATGCTGCCT ACAATTGGAC CCAGAAGAGG TGGACTTGGG TCTGGGGGCT GCATGGGCCT GGGAGGATCA GT TAATACCTTG TGGGGTCAGG

GAGCCCATGT CCCGTGCTGA TGTTATTTCC CCACCAGGTC CGGGCTGTCT CCAACCAGAT TGTGCGCTTC CCCAATGAGA GACTGACCTC CGACCGTGGC GGAGCCCTCA TGTTCATGCA GTGGGGCCAG TTCATTGACC ATGACCTGGA CTTCTCCCCG GAGTCCCCGG CCAGAGTGGC CTTCACTGCA GGCGTTGACT GTGAGAGGAC CTGCGCCCAG CTGCCCCCCT GCTTTCCCAT CAAGGTACCT ACCCTCAGCC AATCTCCCAT GCCCTTGTGT GGCCTCCCCC AAAGGCAAGG TGCTGGGGGT GGGGATCTGG AAGACTGGAG CACCATCCTT AAGGAGCTGC CTGTGGAGCT AGGGTATGAG ACAGAGACAC AAG CACTGTCTCC TCTTCCATCT CAGATCCCAC CCAATGACCC CCGCATCAAG AACCAGCGTG ACTGCATCCC TTTCTTCCGC TCGGCACCCT CATGCCCCCA AAACAAGAAC AGAGTCCGCA ACCAGATCAA CGCGCTCACC TCCTTTGTGG ACGCCAGCAT GGTGTATGGC AGTGAGGTCT CCCTCTCGCT GCGGCTCCGC AACCGGACCA ACTACCTGGG GCTGCTGGCC ATCAACCAGC GCTrTCAAGA CAACGGCCGG GCCCTGCTGC CCTTCGACAA CCTGCACGAT GACCCCTGTC TCCTCACCAA CCGCTCGGCG CGCATCCCCT GCTTCCTGGC AGGTCAGACA GGGAGGAAGG TGGTGTCTTC CCAGGAAACA GCCATCCCTG GGGTCCCAAC TGGGAAGCAA TGGTGGGATG TGGTGAAGGT ACATGGTTTG GGACCTCAGT ATTAGGCACA CCATAAGCAT GGATCTGTGC AC TGAAGAGATG GAGGTCCAGT GAGGGCCAGG AGTTTGGCCC ACCCCGTCTC TCCCATCCCC AGCCCTGGGT CTACCCTGGT AGAAAGACAT TTCTCTGGGA AAGGCTGCAG

TAAATCTGAG CTTGGGGTTT TCAAGGTGAC ACCCGATCAA CGGAAACCCC CAAACTGGCA GCCATGCACA CCCTCTTTAT GCGAGAGCAC AACCGGCTGG CCACCGAGCT GAGACGCCTG AATCCCCGGT GGAATGGAGA CAAACTGTAC AATGAGGCTC GGAAGATCAT GGGGGCCATG GTCCAGGTAA GGAGCTCTGC ATCCCAGCAT CCCCC CTTTGTATCT CCACCCACCA ATAGTAAATT AATGTTGTCA CATTTGACGT GATGACAATA AAGAATATGT CTGAGCCACC CTTTGAAAAG GCAAGGGTAT GGGTGAGTAG CCTCTGGGGA ATGTTCCTCC TGTCTTCCCT TCCAGATCAT CACCTACCGA GACTTTCTGC CCCTGGTTCT GGGCAAGGCC CGGGCCAGGA GAACCCTGGG GCACTACAGG GGGTACTGCT CCAATGTGGA CCCACGGGTG GCCAATGTCT TCACCCTGGC CTTCCGCTTT GGCCACACAA TGCTCCAGCC CTTCATGTTC CGCTTGGACA GTCAGTACCG

GGCCTCCGCA CCCAACTCGC ATGTCCCACT TAGCTCTGCC TTCTTTGCCA GCTGGCGGAT CGTGTATGAA GGTGACCAGG TTTTCCAGGG GGCAAATGGG GGTGAGGGTG GGGAGCATGC CCTCCCCTAG GTGG TCCAGCTGCT TCATGTCTCT CCAGAACTCT GTTTCCTGAC AAACGTTACT AACATACCCG ACTGGCTTGT CCAGCTCTGG GCTAGCTTGG CATCATGTGA TAACCCAAGT AGCTTCCCAG AGGCTGGTCC AATCTGTGCT GCTCACATTC CCTGCCACCA GGGGGCATCG ACCCCATCCT CCGGGGCCTC ATGGCCACCC CTGCCAAGCT GAACCGTCAG GATGCCATGT TAGTGGATGA GCTCCGGGAC CGGCTGTTTC GGCAAGTGAG GAGGATTGGG CTGGACCTGG CAGCTCTCAA CATGCAACGA AGCCGGGACC ACGGCCTTCC AGGTGAGGGG GCTGTCCACC TCTTCTCCCA GCTTTGCTCG GGCCAGGCTG CTCAAGGGGT TCTGGGAAGA CCCTGGTACC

CGACTGCCTG GTAGGTTCTG GTGGCAGAAA CGAGGTGTTT TCACCAAAAG ACAGCGCAAG GCCCTGAGCA GAATTTCCTT GTCTCGAATT ATATGTGACA ATACCGGTAT CACCACGGTT TCAAGGGACA TCTTCAGAGC CAACATCTAC CCTCGGGGCT TTGTGAACTG CAGCCGTATC CCCAGGTTGA ACCTATCAGC CTGGCGAGGG ACATGAGGCT TCTGCAGGTA AGGGGAGGCC ACCTCCAGCA CCCTGGGCTG GTTAAGCCTC ACATCCTTCC CTGGATGGAT GGCTGAGTCC TCTTAGGTCT CTAAGCAGAG AAAACAGAAC TTGTCACTAG GTACTCTTTC CAAGTGGCTT CCCAATGTGC TAGTTTCTGG GCTGACAGTC AATTCCAGGC CCTAGGACTT TGGGGGGAAA TTAGGAGCAT CCAACTA GAATTCCGTG GCCAGGACCC CTGCCAGGGC ACTGACCCAG CCTCCCCTGG GGCAGTGGAG ACCTCGGTCC TGCGAGACTG CATAGCAGAG GCCAAGTTGC TGGTGGATGC

TGCCTACAAT TGGACCCAGA AGAGCATCAA GCAGCGGCTT CGCAGCGGTT CAGCCAGCCC CATGGACCTC CTGTCCTACT TCAAACAACC GGTAGCAGCC ACCAGGACAG TTGTTCGGGC CGCAGATTAT ATGCATGTGG CTTTGGGGCT GCTTGAAGAG AAGTTACAAC CCCAGCGGTC CGGACCCTTC ATTGTCACTG ATGTGCTAAC AGAACCACAG CTGCGGCTGC TGTCCCAGGC CAGTGGCTGT GCTCTCCGGG ACCAGGCCGA GCGCTGCAGC GACAAGTACC GCACCATCAC TGGACGGTGC AACAACAAGA GGAGACCCTT GCTAGGGGCC TCCAACCAGG CTCTGGCTCG CTGGCTGCCC GCCGAGTATG AGGATGGGCT GTCGCTCCCC TTCGGCTGGA CCCCCAGCAG GAGGCGCAAT GGCTTCCTTC TCCCTCTTGT CCGGGCTGTC TCCAACCAGA TTGTGCGCTT CCCCAATGAG AGACTGACCT CCGACCGTGG CCGAGCCCTC ATGTTCATGC AGTGGGGCCA GTTCATTGAC

CATGACCTGG ACTTCTCCCC GGAGTCCCCG GCCAGAGTGG CCTTCACTGC AGGCGTTGAC TGTGAGAGGA CCTGCGCCCA GCTGCCCCCC TGCTTTCCCA TCAAGATCCC ACCCAATGAC CCCCGCATCA AGAACCAGCG TGACTGCATC CCTTTCTTCC GCTCGGCACC CTCATGCCCC CAAAACAAGA ACAGAGTCCG CAACCAGATC AACGCGCTCA CCTCCTTTGT GGACGCCAGC ATGGTGTATG GCAGTGAGGT CTCCCTCTCG CTGCGGCTCC GCAACCGGAC CAACTACCTG GGGCTGCTGG CCATCAACCA GCGCTTTCAA GACAACGGCC GGGCCCTGCT GCCCTTCGAC AACCTGCACG ATGACCCCTG TCTCCTCACC AACCGCTCGG CGCGCATCCC CTGCTTCCTG GCAGGTGACA CCCGATCAAC GGAAACCCCC AAACTGGCAG CCATGCACAC CCTCTTTATG CGAGAGCACA ACCGGCTGGC CACCGAGCTG AGACGCCTGA ATCCCCGGTG GAATGGAGAC AAACTGTACA

ATGAGGCTCG GAAGATCATG GGGGCCATGG TCCAGATCAT CACCTACCGA GACTTTCTGC CCCTGGTTCT GGGCAAGGCC CGGGCCAGGA GAACCCTGGG GCACTACAGG GGGTACTGCT CCAATGTGGA CCCACGGGTG GCCAATGTCT TCACCCTGGC CTTCCGCTTT GGCCACACAA TGCTCCAGCC CTTCATGTTC CGCTTGGACA GTCAGTACCG GGCCTCCGCA CCCAACTCGC ATGTCCCACT TAGCTCTGCC TTCTTTGCCA GCTGGCGGAT CGTGTATGAA GGGGGCATCG ACCCCATCCT CCGGGGCCTC ATGGCCACCC CTGCCAAGCT GAACCGTCAG GATGCCATGT TAGTGGATGA GCTCCGGGAC CGGCTGTTTC GGCAAGTGAG GAGGATTGGG CTGGACCTGG CAGCTCTCAA CATGCAACGA AGCCGGGACC ACGGCCTTCC AGGGTACAAT GCTTGGAGGC GCTTCTGTGG GCTCTCCCAG CCCCGGAATT TGGCACAGCT TAGCCGGGTG CTGAAAAACC AGGACTTGGC

AAGGAAGTTC CTGAATTTGT ATGGAACACC TGACAACATT GACATCTGGA TTGGGGCCAT CGCTGAGCCT CTTTTGCCGG GGGCTCGAGT GGGGCCTCTT CTGGCTTGTC TGTTCGAGAA CCAGTTCAGA AGAGCCGAGA CGGAGACAGG TTCTGGTGGC AGAACGAGGT GTTTTCACCA AAGACAGCGC AAGGCCCTGA GCAGAATTTC CTTGTCTCGA ATTATATGTG ACAATACCGG TATCACCACG GTTTCAAGGG ACATCTTCAG AGCCAACATC TACCCTCGGG GCTTTGTGAA CTGCAGCCGT ATCCCCAGGT TGAACCTATC AGCCTGGCGA GGGACATGAG GCTTCTGCAG GAGTCTATCC CAAGTCTCCA ACTTTTGGAG ACAAGGGGAA GGGGAGGACC ATGAGGCTGC CTTGTCTCCC TGGAGCAAGT GCAGGCTCGT GACGCTTCTG CTGGCTACAG CTCAGAGCTG GGTTCCCCAG CCAGGAGTGA AGGCTGGGGG CTCCTATCAG CAATGGACCT TCCGCCTTGG GAGCCTCTTA

GGTATTAGGC TATGAATCAG CGCCACGTGC AAAGGCTTGG GAGCCAAGCC ATGTGGTCTT GCACCCCAGG CAAGAAAAGT CAGCTGGAGG GTTTACAGCA CTTTCTACTG TTTCCCAGCC CTCCCTCCCC TCCCTCACCA TGACTAAGAG ACCACTCGGT CCTAGCCTCC AGACACCCCA CAATACTCCT CTGAGCCTGA GGCCAGGCAG CATGCTCTGC TTCTACCAAT AAAGCACTGC CGGAATTC CATATGTATG GGAATACTGT ATTTCAGGCA TTATAAGGAA TGAAATTATA GGCCGGGCAT TGTGGCTAAC CCTTGTAATC CTAGCACTTT GAGAGGCTGA AGTGGGCAGA TCACTTGAGC TTCAGAGTTC GAGACCAGCA TGGACAACAT GGTGAAACCC AGTCTCTACC AAAAACACAA AAATATTAGC TGGGTGTGGT GGTGCATGCC TGTAGTCCCA GCTACTCAGG AGGCTGAGGT GGGAGGATCG CTTGAGCCTG GGAGGCAGAA GTTGCAATGA GCAGAGATCG

TGCCACTCCG CTCCAGTCTT GGTGACAGAA TGAGACTCCA TCTCAAAAAT AAATAAATAA ATAAATAAAA TAAATGAAAT GAAATTATAA GAAATTACCA CTTTTTCATG TAAGAAGTGA TCATTTCCAT TATAAGGGAA GGAATTTAAT CCTACCTGCC ATTCCACCAA AGCTTACCTA GTGCTAAAGG ATGAGGTGTT AGTAAGACCA ACATCTCAGA GGCCTCTCTG TGCCAATAGC CTTCCTTCCT TTCCCTTCCA AAAACCTCAA GTGACTAGTT CAGAGGCCTG TCTGGAATAA TGGCATCATC TAATATCACT GGCCTTCTGG AACCTGGGCA TTTTCCAGTG TGTTCCATAC TGTCAATATT CCCCCAGCTT CCTGGACTCC TGTCACAAGC TGGAAAAGTG AGAGGATGGA CAGGGATTAA CCAGAGAGCT CCCTGCTGAG GAAAAAATCT CCCAGATGCT GAAAGTGAGG CCATGTGGCT TGGCCAAATA AAACCTGGCT CCGTGGTGCC TCTGTCTTAG CAGCCACCCT GCTGATGAAC

TGCCACCTTG GACTTGGGAC CAGAAAGAGG TGGGTTGGGT GAAGAGGCAC CACACAGAGT GATGTAACAG CAAGATCAGG TCACCCACAG GCCCTGGCAG TCACAGTCAT AAATTAGCTA ACTGTACACA AGCTGGGGAC ACTCCCTTTG GAAACCAAAA AAAAAAAAAA AAAAAAGAGA CCTTTATGCA AAAACAACTC TCTGGATGGC ATGGGGTGAG TATAAATACT TCTTGGCTGC CAGTGTGTTC ATAACTTTGT AGCGAGTCGA AAACTGAGGC TCCGGCCGCA GAGAACTCAG CCTCATTCCT GCTTTAAAAT CTCTCGGCCA CCTTTGATGA GGGGACTGGG CAGTTCTAGA CAGTCCCGAA GTTCTCAAGG CACAGGTCTC TTCCTGGTTT GACTGTCCTT ACCCCGGGGA GGCAGTGCAG CCAGCTGCAA GGTGAGTTGC C CATATGTATG GGAATACTGT ATTTCAGGCA TTATAAGGAA TGAAATTATA GGCCGGGCAT TGTGGCTAAC CCTTGTAATC

CTAGCACTTT GAGAGGCTGA AGTGGGCAGA TCACTTGAGC TTCAGAGTTC GAGACCAGCA TGGACAACAT GGTGAAACCC AGTCTCTACC AAAAACACAA AAATATTAGC TGGGTGTGGT GGTGCATGCC TGTAGTCCCA GCTACTCAGG AGGCTGAGGT GGGAGGATCG CTTGAGCCTG GGAGGCAGAA GTTGCAATGA GCAGAGATCG TGCCACTCCG CTCCAGTCTT GGTGACAGAA TGAGACTCCA TCTCAAAAAT AAATAAATAA ATAAATAAAA TAAATGAAAT GAAATTATAA GAAATTACCA CTTTTTCATG TAAGAAGTGA TCATTTCCAT TATAAGGGAA GGAATTTAAT CCTACCTGCC ATTCCACCAA AGCTTACCTA GTGCTAAAGG ATGAGGTGTT AGTAAGACCA ACATCTCAGA GGCCTCTCTG TGCCAATAGC CTTCCTTCCT TTCCCTTCCA AAAACCTCAA GTGACTAGTT CAGAGGCCTG TCTGGAATAA TGGCATCATC TAATATCACT GGCCTTCTGG

AACCTGGGCA TTTTCCAGTG TGTTCCATAC TGTCAATATT CCCCCAGCTT CCTGGACTCC TGTCACAAGC TGGAAAAGTG AGAGGATGGA CAGGGATTAA CCAGAGAGCT CCCTGCTGAG GAAAAAATCT CCCAGATGCT GAAAGTGAGG CCATGTGGCT TGGCCAAATA AAACCTGGCT CCGTGGTGCC TCTGTCTTAG CAGCCACCCT GCTGATGAAC TGCCACCTTG GACTTGGGAC CAGAAAGAGG TGGGTTGGGT GAAGAGGCAC CACACAGAGT GATGTAACAG CAAGATCAGG TCACCCACAG GCCCTGGCAG TCACAGTCAT AAATTAGCTA ACTGTACACA AGCTGGGGAC ACTCCCTTTG GAAACCAAAA AAAAAAAAAA AAAAAAGAGA CCTTTATGCA AAAACAACTC TCTGGATGGC ATGGGGTGAG TATAAATACT TCTTGGCTGC CAGTGTGTTC ATAACTTTGT AGCGAGTCGA AAACTGAGGC TCCGGCCGCA GAGAACTCAG CCTCATTCCT GCTTTAAAAT

CTCTCGGCCA CCTTTGATGA GGGGACTGGG CAGTTCTAGA CAGTCCCGAA GTTCTCAAGG CACAGGTCTC TTCCTGGTTT GACTGTCCTT ACCCCGGGGA GGCAGTGCAG CCAGCTGCAA GGTGAGTTGC C CTGCTTTAAA ATCTCTCGGC CACCTTTGAT GAGGGGACTG GGCAGTTCTA GACAGTCCCG AAGTTCTCAA GGCACAGGTC TCTTCCTGGT TTGACTGTCC TTACCCCGGG GAGGCAGTGC AGCCAGCTGC AAGCCCCACA GTGAAGAACA TCTGAGCTCA AATCCAGATA AGTGACATAA GTGACCTGCT TTGTAAAGCC ATAGAGATGG CCTGTCCTTG GAAATTTCTG TTCAAGACCA AATTCCACCA GTATGCAATG AATGGGGAAA AAGACATCAA CAACAATGTG GAGAAAGCCC CCTGTGCCAC CTCCAGTCCA GTGACACAGG ATGACCTTCA GTATCACAAC CTCAGCAAGC AGCAGAATGA GTCCCCGCAG CCCCTCGTGG AGACGGGAAA GAAGTCTCCA

GAATCTCTGG TCAAGCTGGA TGCAACCCCA TTGTCCTCCC CACGGCATGT GAGGATCAAA AACTGGGGCA GCGGGATGAC TTTCCAAGAC ACACTTCACC ATAAGGCCAA AGGGATTTTA ACTTGCAGGT CCAAATCTTG CCTGGGGTCC ATTATGACTC CCAAAAGTTT GACCAGAGGA CCCAGGGACA AGCCTACCCC TCCAGATGAG CTTCTACCTC AAGCTATCGA ATTTGTCAAC CAATATTACG GCTCCTTCAA AGAGGCAAAA ATAGAGGAAC ATCTGGCCAG GGTGGAAGCG GTAACAAAGG AGATAGAAAC AACAGGAACC TACCAACTGA CGGGAGATGA GCTCATCTTC GCCACCAAGC AGGCCTGGCG CAATGCCCCA CGCTGCATTG GGAGGATCCA GTGGTCCAAC CTGCAGGTCT TCGATGCCCG CAGCTGTTCC ACTGCCCGGG AAATGTTTGA ACACATCTGC AGACACGTGC GTTACTCCAC CAACAATGGC AACATCAGGT CGGCCATCAC CGTGTTCCCC

CAGCGGAGTG ATGGCAAGCA CGACTTCCGG GTGTGGAATG CTCAGCTCAT CCGCTATGCT GGCTACCAGA TGCCAGATGG CAGCATCAGA GGGGACCCTG CCAACGTGGA ATTCACTCAG CTGTGCATCG ACCTGGGCTG GAAGCCCAAG TACGGCCGCT TCGATGTGGT CCCCCTGGTC CTGCAGGCCA ATGGCCGTGA CCCTGAGCTC TTCGAAATCC CACCTGACCT TGTGCTTGAG GTGGCCATGG AACATCCCAA ATACGAGTGG TTTCGGGAAC TGGAGCTAAA GTGGTACGCC CTGCCTGCAG TGGCCAACAT GCTGCTTGAG GTGGGCGGCC TGGAGTTCCC AGGGTGCCCC TTCAATGGCT GGTACATGGG CACAGAGATC GGAGTCCGGG ACTTCTGTGA CGTCCAGCGC TACAACATCC TGGAGGAAGT GGGCAGGAGA ATGGGCCTGG AAACGCACAA GCTGGCCTCG CTCTGGAAAG ACCAGGCTGT CGTTGAGATC AACATTGCTG TGATCCATAG TTTTCAGAAG CAGAATGTGA

CCATCATGGA CCACCACTCG GCTGCAGAAT CCTTCATGAA GTACATGCAG AATGAATACC GGTCCCGTGG GGGCTGCCCG GCAGACTGGA TTTGGCTGGT CCCTCCCATG TCTGGGAGCA TCACCCCCGT GTTTCACCAG GAGATGCTGA ACTACGTCCT GTCCCCTTTC TACTACTATC AGGTAGAGGC CTGGAAAACC CATGTCTGGC AGGACGAGAA GCGGAGACCC AAGAGAAGAG AGATTCCATT GAAAGTCTTG GTCAAAGCTG TGCTCTTTGC CTGTATGCTG ATGCGCAAGA CAATGGCGTC CCGAGTCAGA GTCACCATCC TCTTTGCGAC AGAGACAGGA AAATCAGAGG CGCTGGCCTG GGACCTGGGG GCCTTATTCA GCTGTGCCTT CAACCCCAAG GTTGTCTGCA TGGATAAGTA CAGGCTGAGC TGCCTGGAGG AGGAACGGCT GCTGTTGGTG GTGACCAGTA CGTTTGGCAA TGGAGACTGC CCTGGCAATG GAGAGAAACT GAAGAAATCG CTCTTCATGC TGAAAGAGCT '

CAACAACAAA TTCAGGTACG CTGTGTTTGG CCTCGGCTCC AGCATGTACC CTCGGTTCTG CGCCTTTGCT CATGACATTG ATCAGAAGCT GTCCCACCTG GGGGCCTCTC AGCTCACCCC GATGGGAGAA GGGGATGAGC TCAGTGGGCA GGAGGACGCC TTCCGCAGCT GGGCCGTGCA AACCTTCAAG GCAGCCTGTG AGACGTTTGA TGTCCGAGGC AAACAGCACA TTCAGATCCC CAAGCTCTAC ACCTCCAATG TGACCTGGGA CCCGCACCAC TACAGGCTCG TGCAGGACTC ACAGCCTTTG GACCTCAGCA AAGCCCTCAG CAGCATGCAT GCCAAGAACG TGTTCACCAT GAGGCTCAAA TCTCGGCAGA ATCTACAAAG TCCGACATCC AGCCGTGCCA CCATCCTGGT GGAACTCTCC TGTGAGGATG GCCAAGGCCT GAACTACCTG CCGGGGGAGC ACCTTGGGGT TTGCCCAGGC AACCAGCCGG CCCTGGTCCA AGGCATCCTG GAGCGAGTGG

TGGATGGCCC CACACCCCAC CAGACAGTGC GCCTGGAGGA CCTGGATGAG AGTGGCAGCT ACTGGGTCAG TGACAAGAGG CTGCCCCCCT GCTCACTCAG CCAGGCCCTC ACCTACTCCC CGGACATCAC CACACCCCCA ACCCAGCTGC TGCTCCAAAA GCTGGCCCAG GTGGCCACAG AAGAGCCTGA GAGACAGAGG CTGGAGGCCC TGTGCCAGCC CTCAGAGTAC AGCAAGTGGA AGTTCACCAA CAGCCCCACA TTCCTGGAGG TGCTAGAGGA GTTCCCGTCC CTGCGGGTGT CTGCTGGCTT CCTGCTTTCC CAGCTCCCCA TTCTGAAGCC CAGGTTCTAC TCCATCAGCT CCTCCCGGGA TCACACGCCC ACGGAGATCC ACCTGACTGT GGCCGTGGTC ACCTACCACA CCGGAGATGG CCAGGGTCCC CTGCACCACG GTGTCTGCAG CACATGGCTC AAGAGCCTGA AGCCCCAAGA CCCAGTGCCC TGCTTTGTGC GGAATGCCAG CGCCTTCCAC CTCCCCGAGG ATCCCTCCCA

TCCTTGCATC CTCATCGGGC CTGGCACAGG CATCGTGCCC TTCCGCAGTT TCTGGCAGCA ACGGCTCCAT GACTCCCAGC ACAAGGGAGT GCGGGGAGGC CGCATGACCT TGGTGTTTGG GTGCCGCCGC CCAGATGAGG ACCACATCTA CCAGGAGGAG ATGCTGGAGA TGGCCCAGAA GGGGGTGCTG CATGCGGTGC ACACAGCCTA TTCCCGCCTG CCTGGCAAGC CCAAGGTCTA TGTTCAGGAC ATCCTGCGGC AGCAGCTGGC CAGCGAGGTG CTCCGTGTGC TCCACAAGGA GCCAGGCCAC CTCTATGTTT GCGGGGATGT GCGCATGGCC CGGGACGTGG CCCACACCCT GAAGCAGCTG GTGGCTGCCA AGCTGAAATT GAATGAGGAG CAGGTCGAGG ACTATTTCTT TCAGCTCAAG AGCCAGAAGC GCTATCACGA AGATATCTTC GGTGCTGTAT TTCCTTACGA GGCGAAGAAG GACAGGGTGG CGGTGCAGCC CAGCAGCCTG GAGATGTCAG CGCTCTGAGG GCCTACAGGA GGGGTTAAAG CTGCCGGCAC AGAACTTAAG GATGGAGCCA GCTCTGCATT ATCTGAGGTC ACAGGGCCTG GGGAGATGGA GGAAAGTGAT ATCCCCCAGC CTCAAGTCTT ATTTCCTCAA CGTTGCTCCC CATCAAGCCC TTTACTTGAC CTCCTAACAA GTAGCACCCT GGATTGATCG GAGCCTCCTC TCTCAAACTG GGGCCTCCCT GGTCCCTTGG AGACAAAATC TTAAATGCCA GGCCTGGCGA GTGGGTGAAA GATGGAACTT GCTGCTGAGT GCACCACTTC AAGTGACCAC CAGGAGGTGC TATCGCACCA CTGTGTATTT AACTGCCTTG TGTACAGTTA TTTATGCCTC TGTATTTAAA AAACTAACAC CCAGTCTGTT CCCCATGGCC ACTTGGGTCT TCCCTGTATG ATTCCTTGAT GGAGATATTT

ACATGAATTG CATTTTACTT TAATC GAATTCCCAC TCTGCTGCCT GCTCCAGCAG ACGGACGCAC AGTAACATGG GCAACTTGAA GAGCGTGGCC CAGGAGCCTG GGCCACCCTG CGGCCTGGGG CTGGGGCTGG GCCTTGGGCT GTGCGGCAAG CAGGGCCCAG CCACCCCGGC CCCTGAGCCC AGCCGGGCCC CAGCATCCCT ACTCCCACCA GCGCCAGAAC ACAGCCCCCC GAGCTCCCCG CTAACCCAGC CCCCAGAGGG GCCCAAGTTC CCTCGTGTGA AGAACTGGGA GGTGGGGAGC ATCACCTATG ACACCCTCAG CGCCCAGGCG CAGCAGGATG GGCCCTGCAC CCCAAGACGC TGCCTGGGCT CCCTGGTATT TCCACGGAAA CTACAGGGCC GGCCCTCCCC CGGCCCCCCG GCCCCTGAGC AGCTGCTGAG TCAGGCCCGG GACTTCATCA ACCAGTACTA CAGCTCCATT AAGAGGAGCG GCTCCCAGGC CCACGAACAG CGGCTTCAAG AGGTGGAAGC

CGAGGTGGCA GCCACAGGCA CCTACCAGCT TAGGGAGAGC GAGCTGGTGT TCGGGGCTAA GCAGGCCTGG CGCAACGCTC CCCGCTGCGT GGGCCGGATC CAGTGGGGGA AGCTGCAGGT GTTCGATGCC CGGGACTGCA GGTCTGCACA GGAAATGTTC ACCTACATCT GCAACCACAT CAAGTATGCC ACCAACCGGG GCAACCTTCG CTCGGCCATC ACAGTGTTCC CGCAGCGCTG CCCTGGCCGA GGAGACTTCC GAATCTGGAA CAGCCAGCTG GTGCGCTACG CGGGCTACCG GCAGCAGGAC GGCTCTGTGC GGGGGGACCC AGCCAACGTG GAGATCACCG AGCTCTGCAT TCAGCACGGC TGGACCCCAG GAAACGGTCG CTTCGACGTG CTGCCCCTGC TGCTGCAGGC CCCAGATGAG CCCCCAGAAC TCTTCCTTCT GCCCCCCGAG CTGGTCCTTG AGGTGCCCCT GGAGCACCCC ACGCTGGAGT GGTTTGCAGC CCTGGGCCTG CGCTGGTACG CCCTCCCGGC

AGTGTCCAAC ATGCTGCTGG AAATTGGGGG CCTGGAGTTC CCCGCAGCCC CCTTCAGTGG CTGGTACATG AGCACTGAGA TCGGCACGAG GAACCTGTGT GACCCTCACC GCTACAACAT CCTGGAGGAT GTGGCTGTCT GCATGGACCT GGATACCCGG ACCACCTCGT CCCTGTGGAA AGACAAGGCA GCAGTGGAAA TCAACGTGGC CGTGCTGCAC AGTTACCAGC TAGCCAAAGT CACCATCGTG GACCACCACG CCGCCACGGC CTCTTTCATG AAGCACCTGG AGAATGAGCA GAAGGCCAGG GGGGGCTGCC CTGCAGACTG GGCCTGGATC GTGCCCCCCA TCTCGGGCAG CCTCACTCCT GTTTTCCATC AGGAGATGGT CAACTATTTC CTGTCCCCGG CCTTCCGCTA CCAGCCAGAC CCCTGGAAGG GGAGTGCCGC CAAGGGCACC GGCATCACCA GGAAGAAGAC CTTTAAAGAA GTGGCCAACG CCGTGAAGAT CTCCGCCTCG CTCATGGGCA CGGTGATGGC

GAAGCGAGTG AAGGCGACAA TCCTGTATGG CTCCGAGACC GGCCGGGCCC AGAGCTACGC ACAGCAGCTG GGGAGACTCT TCCGGAAGGC TTTTGATCCC CGGGTCCTGT GTATGGATGA GTATGACGTG GTGTCCCTCG AACACGAGAC GCTGGTGCTG GTGGTAACCA GCACATTTGG GAATGGGGAT CCCCCGGAGA ATGGAGAGAG CTTTGCAGCT GCCCTGATGG AGATGTCCGG CCCCTACAAC AGCTCCCCTC GGCCGGAACA GCACAAGAGT TATAAGATCC GCTTCAACAG CATCTCCTGC TCAGACCCAC TGGTGTCCTC TTGGCGGCGG AAGAGGAAGG AGTCCAGTAA CACAGACAGT GCAGGGGCCC TGGGCACCCT CAGGTTCTGT GTGTTCGGGC TCGGCTCCCG GGCATACCCC CACTTCTGCG CCTTTGCTCG TGCCGTGGAC ACACGGCTGG AGGAACTGGG CGGGGAGCGG CTGCTGCAGC TGGGCCAGGG CGACGAGCTG TGCGGCCAGG AGGAGGCCTT

CCGAGGCTGG GCCCAGGCTG CCTTCCAGGC CGCCTGTGAG ACCTTCTGTG TGGGAGAGGA TGCCAAGGCC GCCGCCCGAG ACATCTTCAG CCCCAAACGG AGCTGGAAGC GCCAGAGGTA CCGGCTGAGC GCCCAGGCCG AGGGCCTGCA GTTGCTGCCA GGTCTGATCC ACGTGCACAG GCGGAAGATG TTCCAGGCTA CAATCCGCTC AGTGGAAAAC CTGCAAAGCA GCAAGTCCAC GAGGGCCACC ATCCTGGTGC GCCTGGACAC CGGAGGCCAG GAGGGGCTGC AGTACCAGCC GGGGGACCAC ATAGGTGTCT GCCCGCCCAA CCGGCCCGGC CTTGTGGAGG CGCTGCTGAG CCGCGTGGAG GACCCGCCGG CGCCCACTGA GCCCGTGGCA GTAGAGCAGC TGGAGAAGGG CAGCCCTGGT GGCCCTCCCC CCGGCTGGGT GCGGGACCCC CGGCTGCCCC CGTGCACGCT GCGCCAGGCT CTCACCTTCT TCCTGGACAT CACCTCCCCA CCCAGCCCTC

AGCTCTTGCG GCTGCTCAGC ACCTTGGCAG AAGAGCCCAG GGAACAGCAG GAGCTGGAGG CCCTCAGCCA GGATCCCCGA CGCTACGAGG AGTGGAAGTG GTTCCGCTGC CCCACGCTGC TGGAGGTGCT GGAGCAGTTC CCGTCGGTGG CGCTGCCTGC CCCACTGCTC CTCACCCAGC TGCCTCTGCT CCAGCCCCGG TACTACTCAG TCAGCTCGGC ACCCAGCACC CACCCAGGAG AGATCCACCT CACTGTAGCT GTGCTGGCAT ACAGGACTCA GGATGGGCTG GGCCCCCTGC ACTATGGAGT CTGCTCCACG TGGCTAAGCC AGCTCAAGCC CGGAGACCCT GTGCCCTGCT TCATCCGGGG GGCTCCCTCC TTCCGGCTGC CACCCGATCC CAGCTTGCCC TGCATCCTGG TGGGTCCAGG CACTGGCATT GCCCCCTTCC GGGGATTCTG GCAGGAGCGG CTGCATGACA TTGAGAGCAA AGGGCTGCAG CCCACTCCCA TGACTTTGGT GTTCGGCTGC CGATGCTCCC

AACTTGACCA TCTCTACCGC GACGAGGTGC AGAACGCCCA GCAGCGCGGG GTGTTTGGCC GAGTCCTCAC CGCCTTCTCC CGGGAACCTG ACAACCCCAA GACCTACGTG CAGGACATCC TGAGGACGGA GCTGGCTGCG GAGGTGCACC GCGTGCTGTG CCTCGAGCGG GGCCACATGT TTGTCTGCGG CGATGTTACC ATGGCAACCA ACGTCCTGCA GACCGTGCAG CGCATCCTGG CGACGGAGGG CGACATGGAG CTGGACGAGG CCGGCGACGT CATCGGCGTG CTGCGGGATC AGCAACGCTA CCACGAAGAC ATTTTCGGGC TCACGCTGCG CACCCAGGAG GTGACAAGCC GCATACGCAC CCAGAGCTTT TCCTTGCAGG AGCGTCAGTT GCGGGGCGCA GTGCCCTGGG CGTTCGACCC TCCCGGCTCA GACACCAACA GCCCCTGAGA GCCGCCTGGC TTTCCCTTCC AGTTCCGGGA GAGCGGCTGC CCGACTCAGG TCCGCCCGAC CAGGATCAGC CCCGCTCCTC

CCCTCTTGAG GTGGTGCCTT CTCACATCTG TCCAGAGGCT GCAAGGATTC AGCATTATTC CTCCAGGAAG GAGCAAAACG CCTCTTTTCC CTCTCTAGGC CTGTTGCCTC GGGCCTGGGT CCGCCTTAAT CTGGAAGGCC CCTCCCAGCA GCGGTACCCC AGGGCCTACT GCCACCCGCT TCCTGTTTCT TAGTCCGAAT GTTAGATTCC TCTTGCCTCT CTCAGGAGTA TCTTACCTGT AAAGTCTAAT CTCTAAATCA AGTATTTATT ATTGAAGATT TACCATAAGG GACTGTGCCA GATGTTAGGA GAACTACTAA AGTGCCTACC CCAGCTC-3' (SEQ ID NO: 12372) Human Factor Related Anti-sense Oligonucleotide

5'-CCT CCT TCC TGG TCT GTC TGC CBG BCB BBT TTG GGB BGT GBB CBG TTT TGG BBC CBT GTT TCC CBG TCT CTG BGC TGT GGC GCC CTG CTG CTC TTT CTG CT TCC CTT GGT GGG TTG GGC C GCT GGT TGT TCT GGG GTT C TIG CTG CCC CTT CTG TCC C TGT TTG CTG GTG TCT GCG C CCC CBB CBG BBG BBG CBG BCB BBT TTG GGB BGT GBB CBG TTT TGG BBC CBT GTT TCC TGT GCG CTC GGC CTG GTC CCG G GGG TCT CCT CTT GTT GTT GC TTG CGC CTC CTG CTG GGG GT CC CTC TGT TCT TGT TTT GGG GGC GGG CCC GGC CGT TGT CTT G GTT TGG GGG TTT CCG TTG GGG TTC TCC TGG CCC GGG CCT TGC CC GGC CGT GGT CCC GGC TTC GTTCCT GTC TCC GTC TCG GCT CTT CTG GGG CCT TGC GCT GTC TTT GGT G GCB CCG TCC BGT GBT GGT GCG GTB CTT GTC GCT GCB GCG CTC GGC CTG GTC

CCG GBG BGC GCG CGG GCC GGG GGC TGC TGG G GGT TGG CCC GGG GTG CCC C GCC GCT GGG TGC CCT CGT CCT CTG CGG TC GTG TCT CCT GGC TCT GGT TCC CC GCT GCG CCC GTT GTC CTC TGG GGT GGC CTT C GCT CCC GGG TCT GGT TCT TGT GT TGG GGG TCC CTT TTT GGG CCT GTT GT GGC GTG GCT TGT GTG TTC GGT TTC TGC CCT GTC CTC CGG CGT CCC CGG BGC CTC CCC GGG GCB GGB TGB CTT TTG BGG GGG BCB CBG BTG TCT GGG CBT TGC CBG GTC CTG GGB BCB GBG CCC CGB GCB GGB CCB GGB GTG CGG GCB GCG CGG GCC GGG GGC TGC TGG GBG CCB TBG CGB GGC TGB G CCT CTT TTC TGT TTT TCC C CTC TGC CTT TGT TTG GGT TCG CTT CCT TTC TGC TTC TTC C CTG TGT CTC CTG TCT CCG CTT TTT TCT TC GTC TTT GTT GTT TTC TCT TCC TTG CTG BGC BBG BTB TCT BGB TTC TGG

GGT GGT CTC GBT TTT BBBB GCT TGB GBB GCT GCB BBC BTT BTC CBB BGT BTB TTT GBG GCT CCB BGG BTC BCG BCC BTC TTC CCB GGC BTT TTB BGT TGC TGT CGT BBG TGB GBG CTG BGB GBB BCT GTG BBG CBB TCB TGB CTT CBB GBG TTC TTT TCB CCC GTT CTT GGC TTC TTC TGT C CGT TGG CTT CTC GTT GTC CC TGT GGG CTT CTC GTT GTC CC CCC TTC GGG GGC TGG TGG GGC CGT CCT TGC CTG CTG G GTT CTT GGC TTC TTC TGT CCG T TGG CTT CTC GTT GTC CC TGT GGG CTT CTC GTT GTC CC CCC TTC GGG GGC TGG TGG GGC CGT CCT TGC CTG CTG G TTT TCT CTT TCG CTT TCT TTT CGT CTC CTG TTC CTC CTT TT TTG CTG TTT TTT CTC CTT CTT CTC TCC TTT CTT TTC TTT TCT CTT TCG CTT TCT TTT CGT CTC CTG TTC CTC CTT TT TTG CTG TTT TTT CTC CTT CTT CTC TCC TTT CTT TTC CTC

TGT CTT GTT CTG GTC CTT CGT GGG GCT CTG TGT CGC GTG G GTG CGG CCG TGG CC GGC GGB CCB GGB GTT GGB GCB GGB GCB GGB CGG GCB GGC GGC TCB TGT TTG GBT CGG CBG GBG GCB CTC CTC TGG TTG GCT TCC TTC GCC GGC BCB TGC TBG CBG GBB GBB CBG BGG GGG BBG CBG TTG GGB GGT GBG BCC CBT TBB TBG GTG TCG B TCCCTGTTTC CCCCCTTTCG TTCTGCGTTT GCCTTTGGCG TTTTTTGTTT GTTTTCTCTC TCCGTCTTTC TTCTCCCCT GTGGGBBTTT CTGTGGGGBT GGCBTBCBCG TBGGCBGCTC CBBGBGCTBG CBBBCTCBBB TGCBGBBGCB TCCTCBTGGC TCTGBBBCGG TGGGAATTTC TGTGGGGBTG GCATACACGT AGGCAGCTCC AAGAGCTAGC AAACTCAAAT GCAGAAGCATC CTCATGGCTC TGAAACG GGGGGTGGCT TCCTGCCGCG TCTCTGGGCC GTCCCGTCCC TCGGCCCCGC GCCGCGCTCG

GCTCCTCTCC CTCTGGCCCG GCTCGGGGCG GGGCGGGGCG GTGGGCGGGC GGCGCTGCCC TGCGCGCGGC GCTGGCCCCT GCTGGCCGTC GGCTGCGCGC TGCTGGCTGC CCTGCTGGCC GCGCCGGGGC CTGTCCGCCT CTGCGGGCGC TGTCTCCTGG CTTGTCTTCC GGCTCTTCTG CTGGGGTGGG GCTGGGCGGC CGGCCCGGTG CTGGGGCTCC TCGGGGGGGG GGGCTCTTCC GGGCTGTCTC CCTCCGGGGC GGGGGTTTCT GGCCGTGGGG GTCTTGCCTG GCCTCCGGGC TCCTGCTTGT CTTGCCTTCC TTCTCTGGTC GGTTGTGGCT CGGGGCTCCG TGGGTCCCTG GCGCCCGTTT GTGTTTTGTC TTTTCCCCTG GCGTCCCTGT GCCCCTCTCC TCTCCTTCCT CTGCTTCTCG CTCTCCTTTG TGGGGCCCTC CCTGCTGCTC TTGGTTTTGG GCTTTTTTTC TCTTCCTCCT TTTTCGTGCG TGGGCCTCC GCACGCCTCT TGCCACCTCC TGCGCAGGGC AGCGCCTTGG

GGCCAGCGCC GCTCCCGGCG CGGCCAGCAG GGCAGCCAGC AGCGCGCAGC CGACGGCCAG CATGCTTCCT CCTCGGCTAC CACTCCATGG TCCCGCAGAG GCGGACAGGC GCBCGCCTC TTGCCBCCTC CTGCGCBGGG CBGCGCCTTG GGGCCBGCGC CGCTCCCGGC GCGGCCBGCB GGGCBGCCBG CBGCGCGCBG CCGBCGGCCB GCBTGCTTCC TCCTCGGCTB CCBCTCCBTG GTCCCGCBGB GGCGGBCBGG C GGGGTGGBBB GGTTTGGBGT BTGTCTTTBT GCBCTGBCBT CTBBGTTCTT TBGCBCTCCT TGGCBBBBCT GCBCCTTCBC BCBGBGCTGC BGBBBTCBGG BBGGCTGCCB BGBGBGCCBC GGCCBGCTTG GBBGTCBTGT TTBCBCBCBG TGBGBTGGTT CCTTCCGGGC TTGTGTGCTC TGCTGTCTCT TGGTTCCTTC CGGTGGTTTC TTCCTGGCTC TTGTCCTTTC TCTTGG CCCT TGGC CGGGBGTGGG GGTCCTGGBC GGCBCTGBBG

GCBTCCBGGG CTCCCTTCCB GTCCTTCTTG TCCGCTGCCB GCBCCCCTTC BTTCCBGBGG CTGBTGGCCT CCBCCBGGGB CBTGBTTBGG TBGBBBCTBG GBGGCCGGCC TCCBCCBGGG BCBTGGTCCT TCTTGTCCGC TGCCTCTCTG GGGTTTTCGG TCTGGGTGGG CTTTCCTCCT GGGGCTGCTG CTGGGCTCTT CTTTTTGTTT CTGGCCTGGT GCTCTCTCGT GCCCTTTCCC TTGGGTGTCT TGTTTTTGTG GCCTCCBCCB GGGBCBTG GTCTTTGTTT CTGGGCTCGT GCCCCBTCCC GGCTTCTCTC TGGTTCCGTC CTCTGTGGTG TTTGGCCCTG CTTCCTTTTG CCTGTTGAGG GGGCAGCAGT TGGGCCCCAA AGGCCCTCTC GTTCACCTTC TGGCACGGAGTT GCATCCCCATA GTCAAACTCT GTGGTCGTGT CATAGTCCTC TGTGGTGTTT GGAGTTTCCA TCCCGGCTTC TCTCTGGTTC CAAGGGAGB GGGGGCBGCB GTTGGGCCCC BBBGGCCCTC

TCGTTCBCCT TCTGGCBCGG BGTTGCBTCC CCBTBGTCBB BCTCTGTGGT CGTGTCBTBG TCCTCTGTGG TGTTTGGBGT TTCCBTCCCG GCTTCTCTCT GGTTCCBBGG GB GGGCBCGGGG CBGTGGGCGG GCBBTGTBGG CBBBGCBGCB GGGTGTGGTG TCCGBGGBBT BTGGGGBGGC BGBTGCBGGB GCGCBGBGGG CBGTBGCBBT GBGGBTGBCB GCGBGGCGTG CCGCGGBGBC CTTCBTGGTB CCTGTGGBGB GGCTGTCGGB GGGGGTGTGG TGTCCGCTTG GCGGTTCTTT CGGGTGTTTC TTCTCTGGGT TGGCCTGCTG CTCGTCGTGGT CGCTCCGCTC CCGGGTTCGT CTCGCTCTGT CGCCCCTTCC TTCCTTGTCG TGTTCCTCCC TTCCTTGCCT CT GBTGTTTGTT BCCBBBGCBT CBBGBBTBGC TTTGCTBTCT BBGGBTCBCB TTTBGBCBTB GGBBBBCGCT GTBGGTCBGBB BGBTGTGCTT BCCTTCBCBC BGBGCTGCBG BBBTCBGGBBGG

CTGCCBBGBGBG CCBCGGCCBGC TTGGBGTCBT GTTTBCBCBC BGTGBGGTGC TCCGGTGGCT TTTTGCTTGT GTGCTCTGCT GTCTCTG TTC CTTCCGGTGG TTTCTTCCTG GCTCTTGTCC TTTCTCTTGG CCCTTGGCCC CTTGBGCBGG BBGCTCTGGG GCBGGGBGCT GGCBGGGCCC BGGGGGGTGG CTTCCTGCBC TGTCCBGBGT GCBCTGTGCC BCBGCBGCBG CTGCBGGGCC BTCBGCTTCB TGGGGCTCTG GGTGGCBGGT CCBGCCBTGG GTCTGGGTGG GGCTGGGCTG CBGGCTCCGG GCGGTCCBGCCBTGGGTCTG GGGGCTGGG CTGCBGGCTC CGGGCGGGCG GGTGCGGGCT GCGTGCTGGG GGCTGCCCCG CAGGCCCTGC GGTCCBGCCB TGGGTCTGGG GGCTGGGCTG CBGGCTCCGG GCGGGCGGGT GCGGGCTGCG TGCTGGGGGC TGCCCCGCAG GCCCTGC GCBCCGCCTG GBGCCCTGGG GCCCCCCTGT CTTCTTGGGG

BGCGCCTCCT CGGCCBGCTC CBCGTCCCGG BTCBTGCTTT CBGTGCTCBT GGTGTCCTTT CCBGGGGBGB GBGGGGCTGG TCCTCTGCTG TCCTTGCTGG TGCTCBTGGT GTCCTTTCCG CCCTGGGGCC CCCCTGTCTT CTTGGGGCCT CTTCCCTCTG GGGGCCGTCT CTCTCCCTCT CTTGCGTCTC TCTCTTTCTC TCTCTCTCTT CCCCTTTCCC GCTCTTTCTG TCTCGGTGTC TGGTTTTCTC TCTCCGCTGG CTGCCTGTCT GGCCTGCGCT CTTGGCCTGT GCTGTTCCTC CTCCGGTTCC TGTCCTCTCT GTCTGTCGCC CCCTCTGGGG TCTCCCTCTG GGTGGTGGTC TTGTTGCTTG GGCTGGGCTG CGTGTCTCCB GTGCTCBTGG TGTCCGCTGB GGGBGCGTCT GCTGGCGCTG GTCCTCTGCTGTC CTTGCTGGTG CTCBTGGTGT CCTTTCCGCC CTGGGGCCCC CCTGTCTTCT TGGGGCCTCT TCCCTCTGGG GGCCGTCTC TCTCCCTCTC TTGCGTCTCT

CTCTTTCTCT CTCTCTCTTC CCCTTTCCCG CTCTTTCTGT CTCGGTGTCT GGTTTTCTCT CTCCGCTGGC TGCCTGTCTG GCCTGCGCTC TTGGCCTGTG CTGTTCCTCC TCCGGTTCCT GTCCTCTCTG TCTGTCGCCC CCTCTGGGGT CTCCCTCTGG CGTGGTGGTC TTGTTGCTTG GGCTGGGCTC CGTGTCTCCB GTGCTCBTGG TGTCCGCTGB GGGBGCGTCT GCTGGC CTGCTGBGGC TTGGGTCTCC GGGCGBTTCT CTGCBGBBGB TGCTCBBBGG GCTCCGGCBG TTCCTCCTTG BTCTGGTCGCT GTCGTBCCBG TCGGBCCBGT BBTTCBGBTC BTCBTTGGCT CCTBTTTCTT CTGCBBBCBG CTGBGTGGBG BCBBGBBBBB BGBCTGCCBB GGCCBCGBGG BTTTTCBTGT TGGBTTTTGC GBCGGBCBGT CCCGCGGGGT GCTGAGTTTC TCTGGTTCCT CCGBGCGCBC GTGGTCGCTC CGCGTTTCTC TGGTTCCTCC GGTCCCGCGG GGTGCTGTCT GGTCGCTGTC GTGGCTTGGG TCTCCGGGCG GTTTCCTTCC TTTTCCGC CGGCCCTTCT CACTGGAGGC ACCGGGCAGT CCTCCATGGG AGGGTTGGGC TTGGCCGGGG CTGCCCGGTG CCTCCTCTTG GCTGGTCCCT CGTTGTCCTT GGGCCCCGC TCCCGCTGCT CGGCCTCCGT GTTCTTTGGC CTCTTGCTCC GCCTGCTGTC TTGTCCCGTC CCCTCCTCGC TTGCGTTTCC CTCTTCCTTG TCTTCCAGGC CTTCCTCCGC TTCCGCTGCT GGGGCCCGCG CCGGGGGGGC GCTCGGCTCC GCGGCTTCCT CCCCGGCTGG GGGGTCCTGG TCTCCGGGGC CTGCGGCTCG CGGGCTCGGG GCTGCGTGCG CCGCGCGCGG CGTCCGCGGT GGGTGGCGCT GTCCCGCCGT GGTGTGTCTC CGTTCTCGTC CTGCGCCGTC

CTGGTCTGCC CGTGGGGTCC TGGGCGTGGT GGGGGGCGTC TGGTGCCTCG TCTGCCCCGT GGGGCTTCGG GCTCGGGGCT GTTCGTCCCC CCTGCCGCTC TGTGGCCTCC GGGGCTCCTC GTTTTCGCTG CTTCGGGTGT CCTTCTCGGC GTGTGGCCCC GGGTCCCGGC CCTGCTGGGC TGGGCGGGGT CGCTGCCCTG GGCTTCTGGC CCGTCTGGTT GTCTGTCGGT GCTTGTCTCG GGTTTCTGGC CTCTGTGCTG GGCGCTTCTC TGCCTCCTGC TCCGCCCTCC TGGTGGCTCG GCTGGGGGTG CCCGTGCGGG GGTGGGTGTG GGGTGTTTTC GGGGTCCTCC CCTTCCC GTT TCA TCT TGG CTT TAT CCTCT CCC CTT GTT CCT CCC CTCT CCT GCT CTG GRG TCT CCT C TTC CCT CCC TCC CCT GCC GTG TTG TCT GTG GGT GTC GTT TCG CTC TTG TTG CCC TGG GCC CTT CCC TGC TGG GGG GGA GTT TCA TCT TGG GTT TCB TCT TGG CTT TBT CCTCT CCC CTT GTT

CCT CCC CTCT CCT GCT CTG GRG TCT CCT C TTC CCT CCC TCC CCT GCC GTG TTG TCT GTG GGT GTC GTT TCG CTC TTG TTG CCC TGG GCC CTT CCC TGC TGG GGG GGB GTT TCB TCT TGG GGG GGB GTT TCB TCT TGG CTT T CCGTGTTGTC BGTGGTGCTG CCCGTTTGBG GTBTGGCGCT CCBCCBBTTC CCTTTTCTCC TTGTTTTCCG TTTCTCTTGC CGTCTGTGGT T GCTCAGCCTC CAAAGGAGCC AGCCTCTCCC CAGTTCCTGA AATCCTGAGT GTTGCCTGCC AGTCGCCATG AGAACTTCCT ACCTTCTGCT GTTTACTCTC TGCTTACTTT TGTCTGAGAT GGCCTCAGGT GGTAACTTTC TCACAGGCCT TGGCCACAGA TCTGATCATT ACAATTGCGT CAGCAGTGGA GGGCAATGTC TCTATTCTGC CTGCCCGATC TTTACCAAAA TTCAAGGCAC CTGTTACAGA GGGAAGGCCA AGTGCTGCAA GTGAGCTGGG AGTGACCAGA AGAAATGACG

CAGAAGTGAA ATGAACTTTT TATAAGCATT CTTTTAATAA AGGAAAATTG CTTTTGAAGT AT ATCCTTTAAG TCAATGGACT TTGCATCAGT CACACCATCT TTTGTTACTT TGGACTTCCC CAGCTATGTT CAATAATTAC TGTTCTTCCC TTGGGCCCCA TTGTAATGGC TACAGCCTCG ACAAAAAGTC TACACTTTGA AGCATTAAGG CTCGGACATC AGCACCAAAT TTTACATCTT TACCATCACT TCAAGTGAGG TGAGGAGCCA GTAGCCTGGA CACTGGTCTC ATCTGGTGAA AGACTGTGGG TAATGGAAGC ATTTCTGTGG GGTGCTGGCA GGACATGTGC ATGGCGAGGC AGGTCATCAG CAGCAAGTGA GAGCTGCCTC TTACTTTCTA AAGGTGACAT AGCAAATATA CAAAAAAAAA TAAATAAATT ATTAATTTAG GTAGAGCACA TAAAGGCTTT ATTTCATATT CCATTTCTCT GTATGCTTTC TTCACCAGGA AGAAATAGTT TTAGTGTCAG GAATGAATGA

GTCTGCCCCT CAATTCCAGC CTGCTCAACA CACAAGGAAA CAAAGCCCTG ACAATCAGAG TGACTCCCTG GTGACTAAGC TCCCAGTCCT GGATGCATAT TTGTTTAGCA GTTCTGACAG CATTTGACCC AGCCCTCTCT CTGCATATCC CATCAGAACC TTCTTTTTTT TTTTTTTCTT TGAGACTGAG TCTTGCTCTG TCGGAAGCGA CTCCTGTGCC TCAGCCTCCC AAATACCTGG AATTATAGGC GTAAGCCATC ATGCCTGGCT AATTTTTGTA TTTTTCATGG AGATGGGGTT TTGCCATGTT GGTCAAATTG GTCTCACACT CCTGACCTCA TGTGATCCAC CTGCCTCAGC CTCCCAAACT GCTGGGATGA CAGGTGTAAG CCACCATGCT AGGCTCAGAA ATTTCCTTTT ATAAAAATGT CATTAAGGAT CTTGGCTGCA CAATATCGTT ACCAGCTTCC TTTAAATCCA CTTCTGGCCT GCCAGGAATC AGGTTCTTCA GAACCTGACA TTTTAAATGA AGAGGTCAGG CAGTTCATGA

GGAAAGCCTC ATTGTCCCCA TGTCTCTGTC ACTGCTGCAC CCCTGAGACA TCACAGACAT GGACACTGGG GCCTGCTTGT TTCTCAAACT GCCCTTAGAT CGAAAGAGGG AGGAACCAGG ATGAATGCCA CTCATTTTCC CAAGAAAGGC CCTCTCCTGA GTGCCCGGGA TGGGGCTCTG TCCATTGCCT GGGGCCGCCA ATTGCTACTC TGGGTTACGG AGGAAGGACA GGGTCCTGAG AGACACCAGA GACCTCACAC AGCCCTGAAA AC ATGGGGCT CCTTCATAAG TGTTTCCCAT CACCAACAGG GAGACCACGT GGAGGCCTTG CAGCCCCACT CGGTGCTTCT CCACCAAATC CCAAGGGCAG TGACGCTGAC GTCTGTGGAA AGCAGAGAAA GCCCTGGCTC CCAAAGCCCT GAAGTCCCTG TGGAGCTGAC ATTCCCTGAG TGACGGTGTG AATGGAAGGA ACTCAAGTGC GGGTGGTAGG CCACCTCCTG GCCCAGGCCT GGGTGAACTC TGAGGGGACA CATGTAGTCA CAATCCCATC

CTCCCATTCT CCTTCTCAGA GGAAGGAAGT GGGCATCCAT CTGCCTCATC TCTCTCCCGT GGGGAAGATG GGGAGTTTCA GGGGAACTTT CACATAAATT TCACCAGCTC AGATCTCCTG TGAGGATGGG GCCCACCATG CTCCCGGTGC TGCCAGAGGC CCTGAOCCCC TCCCAGGGTC CCTGGGTTTG AGCCAGCCCT GTATCATCCC CAGGAGCTGA ATGTCAGAGC AATGGATAGA ATTAGATGGA AAGAGCTCTC AATTTGACCT GAGACTGTCC CCAGATACTC AGGAAAAACA GGACGTCGCA CAGAGTGGGC AGCAGGTGAG TGGCAGGTTA TAGGTCCTGA GTTTGAGTTT GTTCTCACGT GAGACAGACC CAGCCCCTCA CTCCATTCAC ACACTGGGTT TTAAATGGTG CAAGATAGGA GCAATTTTCT GGTCCCAAGA GCAGGAGGAA GGGATTTTCT GGGGTTTCCT GAGTCCAGAT TTGCATAAGA TCTCCTGAGT GTGCATTGTT CTTTGAGGAC CATTCTCTGA

CTCACCAGGT AAGTGGCTGA ATTCTAACCT CTGTAATGAG CATTGCACCC AATACCAGTT CTGAACTCTA CCTGGTGACG AGGGACCAGG ACCTTTATAA GGTGGAAGGC TTGATGTCCT CCCCAGACTC AGCTCCTGGT GAAGCTCCCA GCCATCAGCC ATGAGGGTCT TGTATCTCCT CTTCTCGTTC CTCTTCATAT TCCTGATGCC TCTTCCAGGT GAGATGGGCC AGGGAAATAG GAGGGTTGGC CAAATGGAAG AATGGCGTAG AAGTTCTCTG TCTCCTCTCA TTCCCCTCCA CCTATCTCTC CCTCATCCCT CTCTCTCCTT CCTCTCTCTG TGTGTCCCCT CCATCCTTTT CTCCTGCTTC TCTCTCTTCT TCCCTCTCTC TCTTTTTTCT GTCTTTCTTT TTCCTCTCTC CCTAGAGCAT GTCTTTCTTT CTTTCTCTTT CCTTTCTTCT ACCCACACTT TTAGACTGAA TGCCCTATTT AATTGAACAA AGCATTGCTT CCTTCAATAG AAAAGGAGTT TGAGAACCCA ATGGACACCT

CACTCGTTCT TCTAAGCCAA TATGAAGGAG CCCAGTAGCT TGTAAATATC ATCTCTTCAC TGCTTTCCAT GCTACAACTG CTGAGACTAT GGTTGAAACC TGTTAGGTGA CTTTTTAAAT AAAAGGCAGA AATTTTGATT TTATCTAAAG AAAGTAGTAT AGAATGTCAT TTTCTAAATT TTTATATTTA AAGGGTAGAT ACTGCAACCT AGAGAATTCC AGATAATCTT AAGGCCCAGC CTATACTGTG AGAACTACTG CAGCAAGACA CTCTGCCTCC AGGACTTTTC TGATCAGAGG CCCTGAGAAC AGTCCCTGCC ACTAGGCCAC TGCAGGTTCA CAGGACAGGG TACAGCCCAT TGAAACCTAC TTTTAAACCT GGATGCCTAA CCTTCATTTT CTCCTTGATA TTATGAAAAT AAAATAAAAA CCATGAAAGG ATAAAAGAGG GAGAGTGGAA GGGAAGGATG GAGAAAGGGA AAAAGAAAAT TTGAGAGTAA ATCCTAAAAC AATTAATCTA ATAGATATCA TCTTGTGAAA

TCCTCATTTT ACCAATCTTA TTTATGAGTC CTGGGTTTTG TGAGAACAAT GGGGTTCTGA GAGGCACCAG AGACCTCATG TTTTCCAAAA CCTAGAACAG TATAATGAAG GAAGGCGGGG AGGCAGGGAG GCAGGGAGGC AGGGAGGCAG GGAGGCGGGC AGGTGGGGAG GGAGGGACGG AAGGAGGGAG GGAGGGAGGG AGGGAGGGAG GGAGGGATAA AAAAAGAAGA ATGAGGTTGA AACCAGGACT TAGATATTAG AAACAAGCCA TTACAAAATT TATTTCTATG GTTAATTGTG GTTTTCAACT GTAAGTTACT TGGTGTTAAT TTCCTATTAA ACAATTTCAG TAAGTTGCAT CTTTTTATCC CATCTCAGGT CAAATACTTA ACAGACTAAA TGATTTGAAA AAGCAAAAGT TTACTGGCTT GTGTGTGTTA AAATGGAGGT ATGGTGGCTT TGATATTATC TTCTTGTGGT GGAGCTGAAT TCACAAGAGA TCGTTGCTGA GCTCCTACCA GACCCCACCT GGAGGCCCCA

GTCACTCAGG AGAGATCAGG GTCTTTCACA ATCAGGTTCT ACAAAAATAA ACATCCCCCC AACCACAGCA GTGCCAGTTT CCATGTCAGA AACTTAGATC CAAATGACTG ACTCGCGTCT CATTATCATG ATGGAAAAGC CCAGGCTTGA GAAAGAAGCC CGCTGCGGAT TTACTCAAGG CGATACTGAC ACAGGGTTTG TGTTTTTCCA ACATGAGTTT TGAGTTCTTA CACGCTGTTT GCTCTTTTTG TGTGTTTTTT CCCTGTTAGG TGTTTTTGGT GGTATAGGCG ATCCTGTTAC CTGCCTTAAG AGTGGAGCCA TATGTCATCC AGTCTTTTGC CCTAGAAGGT ATAAACAAAT TGGCACCTGT GGTCTCCCTG GAACAAAATG CTGCAAAAAG CCATGAGGAG GCCAAGAAGC TGCTGTGGCT GATGCGGATT CAGAAAGGGC TCCCTCATCA GAGACGTGCG ACATGTAAAC CAAATTAAAC TATGGTGTCC AAAGATACGC AATCTTTATC CTAGTAATTG TGGTCATTGG GTGATGTTGG

TTTGGGCAGG CCATCTCTAA TATCCTTGAA ACACCTTTTT CTGCTCTCCA GGAAGGGGTC AGGGCTGCCA CAGCGGGGCT TGGAGTGCTT TCCAGGGTCA CAGGCATCTG TATTCTTTGG ATTCCTTGAC CTTCCCCATT TATTCCCGGC ATTTTCCTAA AACGTGTGCT TTGCTCCTCC TGCATCCTCC CCTTGCATGC CCTCACCTAC CCCACATCTT CCCTAAAAAA AGCAAGCCCA ACTCAAAGAC CAGTTCCCTC ATGGAATCAT AGTGGATCTG CCAAGGGAGG GGATGCCCAG TCCTCTGTTC TTCACAAGAC TCCCTTCTTC TGGCTAAGGT TTCTTATGCA ATTAT CTGCAGTGGT AAAAAGATTC TATATCTGCT GTTTGATGAA TGCAGCACCC ACTAGCCACA TAGTGCTCGT GAGCACTTGC AATGCGGCTA GGGTGATTTC AATTAACCTA AAAGAGAACA GCCACAGGGA GCATGTGGCT GCCATATTGG ATGGTGCTGC TTTGAGAACA AAATGAGAGA AATGAAGCCT

CTATTTACCT TGGTTGGCGG AACACATTGA AGGGACTCTG TATTGATACC AGGCTTCAAA CTTTGGGAAG TGTACTGGCC AACTTAAACA CATCCACAGG AGAATGAAGA GGTTTGGGAA GGGACCAGAA ACCAGGCATT GAGGACAATG AGAAGAGTTT TTCAAAAGTG GAATTACTGC AAAAAGTGGA AAAATAGCCT TTGGATGGAA GTTACTGATG AGACAATTTC CATCGGTGTG AAAGCCATCT TTCCAACAGA GATCTGCAAC ATGAGAATGT ACTGTCTCCT AGGGTAGCGA TGGCCTCTTG TATTAGTCCG CTCAGGCTAC CAGATTTATC GTTTAAACTG CCCATAAACA GACCAGGCAG TTTAAACAAC AGAAATTTAT TTCCTCGCAG TCCTGGAGGC AGGAAGTCTG CGATCAAGGT GGAAGCAGGG TTGGCTTCTT CTCAGGTGTC TGTCCTTGGC TGGTAGATGA CCGCCGCCTC CCTGGGTCCT CACATGGTCT TTCCTCTGTG TGTGTCTGTC CCAATCTCTT

CTTATAAGGA TGCAAGTCTT ATGGATCAGA GCACACCCCA ATGACCGTGT TTAACTTGAA TCACCTCTTT AAAGTTTCTC TCTCCAAATA CAATCACCTC CTGAGGCACT GTTAGGGCTT CGACACAGGA ATTCTTTTCC TAGGGGATTC AGTTCAGTCC AAAACGCCTA CCAGTGGAGA CTTGCAACAT GGCGGCCTGC TGGTCCCTCG CCAGGAATAT CACAGGCGAC TGTTCCCTGT TGCATGGAAT AGAAGGCTAT TCCAGAGTAC TGTCTCTATT TATCAGATCT GGGATACTGG GAGAAGGGCA AAATAAAGTC CAAGTAGAAA AAAAAACTAT GAAAGTTTTA GAGAGTAACC ATAATTTCAG CCCGATGTGA AACGATCCTA GATTTCAGCT GAAATAGTGA TGTGGGAAGT GAGGGGGCCG GGATTCAAGG CAGAGGGAAC AGCGTAACTG AAGGCATGGA AGGAGGGAAG TGTAGGCTGT GTTTGAAGAG TGGCAGCTGC TTCCACATTT CTAAAACACA GGATGTGATT

TTGGGGTGTG TTGAGACAAG GCAGAAAACT TGTTTGGAAA AATAACTTGA ATTCCCTGCA CATTTAAAAT CTCTCAGCAG AAGAAAACCC CACTCAGAAC CCCACTGTTC ATTCCTTGGC TTGTATTTGG SCACAGCTGG CATAGCCCCA GACTGAGTAA GCTCTTCAGA CACCTCATTT CATGAGTAGC CCCAAAGATC AATCATGGGC CAATTTCTTG GAAGAGAAGA CTCTCCGGTG TTTTGCAGTT ATTTGTTCTG CTTTCGCGAG ATGTTCTCAA ATCGTTGCAG CTACAAGCCA TGAGTCTGAA GTGTTTGTGT TCCCTCCTTA CAGGTGGTAA CTTTCTCACA GGCCTTGGCC ACAGATCTGA TCATTACAAT TGCGTCAGCA GTGGAGGGCA ATGTCTCTAT TCTGCCTGCC CGATCTTTAC CAAAATTCAA GGCACCTGTT ACAGAGGGAA GGCCAAGTGC TGCAAGTGAG CTGAGAGTGA CCAGAAGAAA TGACGCAGAA GTGAAATGAA CTTTTTATAA GCATTCTTTT AATAAAGGAA

AATTGCTTTT GAAGTATACC TCCTTTGGGC CAAAATGAAT CTTGTGTCTC AATTGGAAGA GGTAAAGAAG TAGGGGGTTA GGGTGCATGG GTTGGAACGT GAGACAGGTC GAACCACAAA GCCTGCCTGG AAAAGGGGAG TGACGTCCTA GGCTTCAGTG ATGTCACCTC CACTTTGTTT GATCCACAAA CCAACAGGTG ACTGATTTTG GTCAGCTCAG CCTCCAAAGG AGCCAGCCTC TCCCCAGTTC CTGAAATCCT GAGTGTTGCC TGCCAGTCGC CATGAGAACT TCCTACCTTC TGCTGTTTAC TCTCTGCTTA CTTTTGTCTG AGATGGCCTC AGGTGGTAAC TTTCTCACAG GCCTTGGCCA CAGATCTGAT CATTACAATT GCGTCAGCAG TGGAGGGCAA TGTCTCTATT CTGCCTGCCC GATCTTTACC AAAATTCAAG GCACCTGTTA CAGAGGGAAG GCCAAGTGCT GCAAGTGAGC TGGGAGTGAC CAGAAGAAAT GACGCAGAAG TGAAATGAAC TT GAATTCACAT

TTCTCACCTT TTGATGTATT AAGAAAGTAT GGAGAAATAT ATCCTCTATC AAATTTTCAT GCCTTCAATA ATTTCTAATT CATCAGTCAG TGTTTTTCCA TCCTTTACTG TGATGATGCC CTTTCTTCCA AACTTTTTCA TTGCATCAGA GATGATGTTA CCAATTTCTT TGTCTCCATT TGCAGAAATT GTAGCAACCT GTGCAATTTC TTCAGGTTTG GTCACAGGTT TAGACTGCTT TTTAAGTTCA GCAATTACAG CATCAACAGC TAACATCACA CCTCTCTTGA TTTCCACTGG ATTAGCACCT TTGCTAACCT TCTGGAAGGC TTATTTGGAA ATAGAGCATA CCAGTACAGC AGCAGTGATA GTGCCATCCC CCAGTCTCTC CATTTGTGTT ATTGGCAACA TCTTGGACAA GTTTAGCTCC AATGCTTTTA TATTTATCCT TTAAGTCAAT TGACTTTGCA TCAGTCACAC CATCTTTTGT TACTTTGGGA CTTCCCCAGC TATGTTCAAT AATTACTGTT CTTCCCTTTG GCCCCATTGT

AATGGCTACA GCATCGACAA AAAGTCTACA CTTTGAAGCA TTAAGGCTCA GACATCAGCA CCAAATTTTA GATCTTTACC ATCACTTCAA GTGAGGTGAG GAGCCAGTAG CCTGGACACT GGTCTCATCT GGTGAAAGAC TGTGGGTAAT GGAAGCATTT CTGTGGGGTG GTGGCAGGAC ATGTGCATGG TGAGGCAGGT CATCAGCAGC AAGTGAGAGC TGCCTCTTAC TTTCTAAAGG TGACATAGCA AGTATACAAA AAAAAATAAA ATATTAATTT AGGCAGAGCA CATAAAGGCT TTATTTCATA TTCCATTTCT CTGTATGCTT TCTTCACCAG GAAGAAATAG TTTTAGTGTC AGGAATGAAT GAGTCTGCCC CTCAATTCCA GCCTGCTCAG CACACAAGGA AACAAAGCCC TGACAATCAG AGTGACTCCC TGGTGACTAA GCTCCAGTCC TGGATGCATA TTTGTTTAGC AGTTCTGACA GCATCTGACC CAGCCCTCTC TTTGCATACC CCACCAGAAC CTTCTTTTTT

TTTTTTTTTC TTTGAGACTG AGTCTTGCTC TGTCGGAAGC GATTCCCGTG CCTCAGCCTC CCAAATACCT GGAATTATAG GCGTAAGCCA TCATGCCTGG CTAATTTTTG TATTTTTCAT GGAGATGGGG TTTTGCCATG TTGGTCAAAT TGGTCTCACA CTCCTGACCT CATGTGATCC ACCTGCCTCA GCCTCCCAAA GTGCTGGGAT GACAGGTGTA AGCCACCATG CTAGGCTCAG AAATTTCCTT TTATAAAAAT GTCATTAAGG ATCTTGGCTG CACAATATCG TTACCAGCTT CCTTTAAATC CACCTCTGGC CTGCCAGGAA TCAGGGTTCT TCAGAACCTG ACATTTTAAA TGAAGAGGTC AGGCAGGTCA TGAGGAAAGC CTCATTGTCC CCATGTCTCT GTCACTGCTG CACCCCTGAG ACATCACAGA CATGGACACT GGGGCCTGCT TGTTTCTCAA ACTGCCCTTA GATCGAAAGA GGGAGGAACC AGGATGAATG CCACTCATTT TCCCAAGAAA GGCCCTCTCC TGAGTGCCCG

GGATGGGGCT CTGTCCATTG CCTGGGGCCG CCAATTGCTA CTCTGGGTTA CGGAAGAAGG ACAGGGTCCT GAGAGACACC AGAGACCTCA CACAGCCCTG AAAACATGGG GCTCCTTCAT AAGTGTTTCC CATCACCAAC AGGGAGACCA CGTGGAGGCC TTGCAGCCCT ACTCGGTGCT TCTCCACCAA ATCCCAAGGG CAGTGACGCT GACGTCTGTG GAAAGCAGAG AAAGCCCTGG CTCCCAAAGC CCTGAAGTCC TGTGGAGCTG ACATTCCCTG AGTGACGGTG TGAATGGAAG GAACTCAAGT GCGGGTGGTA GGCCACCTCC TGGCCCAGGC CTGGGTGAAC TCTGAGGGGA CACATGTAGT CACAATCCCA TCCTCCCATT CTCCTTCTCA GAGGAAGGAA GTGGGCATCC ATCTGCCTCA TCTCTCTCCC GTGGGGAAGA TGGGGAGTTT CAGGGGAACT TTCACATAAA TTTCACCAGC TCAGATCTCC TGTGAGGATG GGGCCCACCA TGCTCCCGGT GCTGCCAGAG GCCCTGAGCC CCTCCAGGGT CCCTGGGTTT GAGCCAGCCC TGTATCATCC CCAGGAGCTG AATGTCCGAA CAATGGATAG AATTAGATGG AAAGAGCTCT CAATTTGGCC TGAGACTGTC CCCAGATACT CAGGAAAAAC AGGACGTCGC ACAGAGTGGG CAGCAGGTGA GTGGCAGGTT ATAGGTCCTG AGTTTGAGTT TGTTCTCACG TGAGACAGAC CCAGCCCCTC ACTCCATTCA CACACTGGGT TTTAAATGGT GCAAGATAGG AGGAATTTTC TGGTCCCAAG AGCAGGAGGA AGGGATTTTC TGGGGTTTCC TGAGTCCAGA TTTGCATAAG ATCTCCTGAG TGTGCATTGT TCTTTGAGGA CCATTCTCTG ACTCACCAGG TAAGTGGCTG AATTCTAACC TCTGTAATGA GCATTGCACC CAATACCAGT

TCTGAACTCT ACCTGGTGAC CAGGGACCAG GACCTTTATA AGGTGGAAGG CTTGATGTCC TCCCCAGACT CAGCTCCTGG TGAAGCTCCC AGCCATCAGC CATGAGGGTC TTGTATCTCC TCTTCTCGTT CCTCTTCATA TTCCTGATGC CTCTTCCAGG TGAGATGGGC CAGGGAAATA GGAGGGTTGG CCAAATGGAA GAATGGCGTA GAAGTTCTCT GTCTCCTCTC ATTCCCCTCC ACCTATCTCT CCCTCATCCC TCTCTCTCCT TCCTCTCTCT GTGTGTCCCC TCCATCCTTT TCTCCTGCTT CTCTCTCTTC TTCCCTCTCT CTCTTTTTTT CTGTCTTTCT TTTTCCTCTC TCCCTAGAGC ATGTCTTTCT TTCTTTCTCT TTCCTTTCTT CTACCCACAC TTTTAGACTG AGTAGACTGA ATGCCCTATT TAATTGAACC AAGCATTGCT TCCTTCAATA GAAAAGGAGT TTGAGAACCC AATGGACAAC TCACTCGTTC TTCTAAGCCA ATATGAAGGA GCCCAGTAGT TTGTAAATAT

CATCTCTTCA CTGCTTTCCA TGCTACAACT GCTGAGACTA TGGTTGAAAC CTGTTAGGTG ACTTTTTAAA TAAAAGGCAG AAATTTTGAT TTTATCTAAA GAAAGTAGTA TAGAATGTCA TTTTCTAAAT TTTTATATTT AAAGAGTAGA TACTGCAACC TAGAGAATTC CAGATAATCT TAAGGCCCAG CCTATACTGT GAGAACTACT GCAGCAGACA CTCTGCCCCC AGGACTTTTC TGATCAGAGG CCCTGAGAAC AGTCCCTGCC ACTAGGCCAC TGCAGGTTCA CAGGACAGGG ACAGCCCATT GAAACCAACT TTTAAACCTG GATGCCTAAC CTTCATTTTC TCCTTGATAT TATGAAAATA AAATAAAAAC CATGAAAGGA TAAAAGAGGG AGAGTGGAAG GGAAGGATGG AGAAAGGGAA AAAGAAAATT TGAGAGTAAA TCCTAAAACA ATTAATCTAA TAGATATCAT CTTGTGAAAT CCTCATTTTA CCAATCTTAT TTATGAGTCC TGGGTTTTGT GAGAACAATG

GGGTTCTGAG AGGCACCAGA GACCTCATAT TTTCCAAAAC CTAGAACAGT ATAATGAAGG AAGGAGGGAA GGAGGGAGGG AGGGAGGGAA GGAGGGAAGG AGGGAGGGAG GGAGGGAAAC AAAAAGAAGA ATGAGGTTGA AACCAGGACT TAGATATTAG AAACAAGCCA TTACAAAATT TATTTCTATG GTTAATTGTG GTTTTCAACT GTAAGTTACT TGGTGTTAAT TTCCTATTAA ACAATTTCAG TAAGTTGCAT CTTTTTTATC CCATCTCAGA TCAAATACTT AACAGACTAA ATGATTTGAA AAAGCAAAAG TTTACTGGCT TGTGTGTGTT AAAATGGAGG TATGGTGGCT TTGATATTAT CTTCTTGTGG TGGAGCTGAA TTCACAAGAG ATCGTTGCTG AGCTCCTGCC AGACCCCACC TGGAGGCCCC AGTCACTCAG GAGAGATCAG GGTCTTTCAC AATCAGGTTC TACAAAAATA AACATCCCCC AAACCACAGC AGTGCCAGTT TCCATGTCAG AAACTTAGAT

CCAAATGACT GACTCGCGTC TCATTATCAT GATGGAAAAG CCCAGGCTTG AGAAAGAAGC CCGCTGCGGA TTTACTCAAG GCGATACTGA CACAGGGTTT GTGTTTTTCC AACATGAGTT TTGAGTTCTT ACACGCTGTT TGCTCTTTTT GTGTGTTTTT TCCCTGTTAG GTGTTTTTGG TGGTATAGGC GATCCTGTTA CCTGCCTTAA GAGTGGAGCC ATATGTCATC CAGTCTTTTG CCCTAGAAGG TATAAACAAA TTGGCACCTG TGGTCTCCCT GGAACAAAAT GCTGCAAAAA GCCATGAGGA GGCCAAGAAG CTGCTGTGGC TGATGCGGAT TCAGAAAGGG CTCCCTCATC AGAGACGTGC GACATGTAAA CCAAATTAAA CTATGGTGTC CAAAGATACG CAATCTTTAT CCTAGTAATT GTGGTCATTG GGTGATGTTG GTTTGGGCAG GCCATCTCTA ATATCCTTGA AACACCTTTT TCTGCTCTCC AGGAAGGGGT CAGGGCTGCC ACAGCGGGGC TTGGAGTGC GAATTCCCTG

TAAGCCCTGT TACAGGGGCT GCACCCCAGA TACAACCTGA CCTGTGTCCA AGGCGGGCAA CTCAACCCTT AGATATTGAA TGGGTCCCAT GGCACCAATG CTTAAACACC AGCAGCCCTC ACAACCACAG ATCGTGTTTT AAGGATGAGG AGGTAGTTCT CTGGATGCAC AGGCTTCAAT CCAAATGGGC TCATGACGCC GCAGCACACA CCCAGTCTGC AGCCTGAAGA GTTGGAGCAT TGCATTCACA GAAAGCATCC AGACATGATC ATGGGCTCAG GGATACACCT GTTCTCCGAT GTGTACCAGT GAAGGATGGA AACTCCTATG CCTCCCAGAA AGCACCACTC AAGCTTTTGC TGAATGCTTC TCTGAAGGCC CACAAGGCTG AGAGGCTGTG CAACACCAGC AGTAAAGTGA ATGCCCAGAC TCCCACCTCC TTTCTTGGGT GGCCATCTGG AAAGGCCACT CCCACCCTGA TGGCTAATGC CTCAGACCAG TTCTTGGCCC AGATGATCCT AGACAATTGT TTAAGCTTAA ACTGTTCATT

GGCCAAGCAA ACAGGTGATA GTACCTCTGG GGAACCACAT GCCGCGTGTA CATCCAGATC TCAGGAGAAC CCAAAAATGT CTGTTCCACA TAGCAACAGA AGCCCAGGTA GCACTCAGTC TCACCTGGGT GTTCTCCAAC ATCCCAGCTC AGCCAAATGG CTTTCATTAG TTTTTATGGT TAGACCCCAG GTCCTCGGGA CACTGCTTTA GAAACACATT CCAAATCCTC CTCTGTGTGC AGGTGGCATT CCTATCCCAA TCTCTTTGCA GGGCGTATAC TGTGATACGC AGCCAGGCTG TCCCAGAGGC CTTAAATATT CCCTTGGTGC AGGTAGTTCA GCTTAGCCAC AGCCAATGCA TCACAGGGTC AACTGTGTTA GGAGCCATTG AGAATCCATA GTTGGTTGCT GCCTGGGCCT GGCCAGGGCT GACCAAGGTA GATGAGAGGT TCCTCTGTGG AGTTCTACTT TAACCTCACC TTCCCACCAA ATTTCTCAAC TGTCCTTGCC ACCACAATTA TTTAATGGAC CCAACAGAAA GTAACCCCGG

AAATTAGGAC ACCTCATCCC AAAAGACCTT TAAATAGGGG AAGTCCACTT GTGCACGGCT GCTCCTTGCT ATAGAAGACC TGGGACAGAG GACTGCTGTC TGCCCTCTCT GGTCACCCTG CCTAGCTAGA GGATCTGTAA GTACTACAAA ACTTAAACTT TACACTGAGT TTTCATCATT GAAGCTATGC CTCCAATCTG ACCTCTGACT GTGGGGCCGC CCCAGAGGGA CCCAGCGGGT GAATCCCTGC TAGGAACGTC TGTCCGGACC TCTGGTGACT GCTGGGGACG ATGGCTTCCA GCTAACTTAA TAGAGAAACT CAAGCAGTTT CCTTCTAAAT ACACATGTCA CATGTCCTGG TTGACATGTC CAGTAAGAAG ACTATCACAG GTCTTTGGAA CATTCTTTTG AGAGAAACCT ATTTAGGTCC TTGGTCTGTT TTTCAATCAG GTTGTTTGAT TTTTGCTATT GAGTTGTTGG AATTCCTTAT GTATTCAGAT ATTTGCCCCT TCTGCCATGT AGGTTTTGCA AATATTTTCT CTCATTTTCT

GGGTTATCTT TTCACTCGGT TGATTGTTTC CTTTGCTGTG CAGATGCTTT AGCGTTAAAT GAAGCCACAC TTGTCTATTT TCCCTTTTAT TGCCTGTGCC TTTGGTGTCA TAGCCAAGAA ATCATTACCT ACATCAATGT CAAAAGCTTT ATCCTT CTAT ACACTTCTAG TAGTTTATGG TTTCAGTTGT TACATTTAGG TTTTCAATTC ATTCTGAGTT GATGTTCCTA CATGGTGTGA GATAAAGATT TAAATACATA CATATATAAA ATCATGAGGT AGTGTACACT ATAAATATAC AATTGTTAAT TGTTACTCAA GTCTAAGTAG AGGTGGAAAT AATAAACTTT CTTTTTTTTA CTTAAACCAC TCTGTGTCAC TGAGCTGATT TCACCTTTAG CCTGATAAAA TCATTGTCCT CTCCACCCTG ATTCCTACAG GAGACTACTC ACCCCATAAC CTCAAAAACC TCTTCATGAG GATGGTAAGT CACCTGAATC CTGAAGTGAA TTACTCGCTA TTCCATTGGA ACTCATATAG GACACCAGAA

TCTAGACCTC CAGAGAACAG CAGGACCCAT CTTCAGAAAA TAAGAAGCAT TTGTTCCCTG AGCCTGTTGA ATCAAAGTGC AATTTCTATT CTTTTTGGAA TGTTAAAAAG TGAATCATAA TATTTAAGCA GGTGAACCCA CGAGTAACAT AGCAGGGTCT TTCTTGTCAT TATTAGCTCC AACCTAGCAC AGACATTAAA GGTACAGATG TATACTAGCA TGAAACTGGG AGAACAGGAG CATTCGAGCA ACCTTGAGAC CAATGGGCCT CTCTTATAAA ATGCACACCT CCTCTCACTG AGATTGAGGA AGGTTTCTTG TCTCCGAGCC TTCTCCCAGT AGAGCTATAA ATCCAGGCTG GCTCCTCCCT CCCCACACAG CTGCTCCTGC TCTCCCTCCT CCAGGTGACC CCAGCCATGA GGACCCTCGC CATCCTTGCT GCCATTCTCC TGGTGGCCCT GCAGGCCCAG GCTGAGCCAC TCCAGGCAAG AGCTGATGAG GTTGCTGCAG CCCCGGAGCA GATTGCAGCG GACATCCCAG AAGTGGTTGT

TTCCCTTGCA TGGGACGAAA GCTTGGCTCC AAAGCATCCA GGTGAGAGAG GCAGGCATGC AGAGCTGCTA AGTCTAGAGG GAAGGACGGG AGAGAGGTTC CAGAGTTGGG TCTCAGCAGT CTATGTCACT GAGGTGGCTT CACTTAGAAT CTCTGGGCAT TGATTTTCTC ATCTAGAAAT TGAACAGAGA GCCAAATAAA CCTGAGAAAC TTTATTTCTC CAAAGACTTG ATTCCAAGAA ACATCTGTGA AATTCACTAA GTTTAAGATA TGAAGAGACA GACTAGTTAT TTCTGGATCT AAACAAGTAG ACTTAGTTGT AAAGAGAACA TTTTACTCTA TCTACAGAAG AGCTTTTAAA AACTGCAGCC AAGCCTGAGG GTAAGTTCAG GTGTGTGTGT GATGGGGCAG GAATGCAAAA ATGAGAGCAA AGGAGAATGA GTCTCAAATT CTGTGTGACA AGCACTGCTC TGCGTGTTTA TTCCTATCGA CTGAGGTTGT TCGTGCTACC GGCTGCAATG CAGCCAGCAT CACCTGTCAG

CTAGCATGTG ACTTCCCCGA GATTCTTTTT CTTACCCACT GCTAACTCCA TACTCAATTT CTCATGCTCT CCCTGTCCCA GGCTCAAGGA AAAACATGGA CTGCTATTGC AGAATACCAG CGTGCATTGC AGGAGAACGT CGCTATGGAA CCTGCATCTA CCAGGGAAGA CTCTGGGCAT TCTGCTGCTG AGCTTGCAGA AAAAGAAAAA TGAGCTCAAA ATTTGCTTTG AGAGCTACAG GGAATTGCTA TTACTCCTGT ACCTTCTGCT CAATTTCCTT TCCTCATCTC AAATAAATGC CTTGTTACAA GATTTCTGTG TTTCCACCTC TTTAATGTGT GATATGTGTC TGTGTCAAGA CACTTGGGAT ACACGTACCA AAACGCAAAA TCAAATTTTT GAACAATATA CCTACCTTGC TATAGAAGAC CTGGGACAGA GGACTGCTGT CTGCCCTCTC TGGTCACCCT GCCTAGCTAG AGGATCTGTG ACCCCAGCCA TGAGGACCCT CGCCATCCTT GCTGCCATTC TCCTGGTGGC CCTGCAGGCC

CAGGCTGAGC CACTCCAGGC AAGAGCTGAT GAGGTTGCTG CAGCCCCGGA GCAGATTGCA GCGGACATCC CAGAAGTGGT TGTTTCCCTT GCATGGGACG AAAGCTTGGC TCCAAAGCAT CCAGGCTCAA GGAAAAACAT GGACTGCTAT TGCAGAATAC CAGCGTGCAT TGCAGGAGAA CGTCGCTATG GAACCTGCAT CTACCAGGGA AGACTCTGGG CATTCTGCTG CTGAGCTTGC AGAAAAAGAA AAATGAGCTC AAAATTTGCT TTGAGAGCTA CAGGGAATTG CTATTACTCC TGTACCTTCT GCTCAATTTC CTTT GATCAAAATT TTTACCTATT ATGCATTTGA TATATAAATA AGTATATAAA TGCACACACA GACACAGCAA TGATGGTGAA CAGTCTTCAT ACAATTATAT GGATGAATCT CATAAAATGC TGAGTTAAAG AAATCAGACC AAAGAACATA TACTGAAAGA TTCTCTCTAT ATACAAAGTT CAAAAATAGG TGGACCAATT CATGGTGGTG TTAGAAATCA

GAAGAGAGGC TACCTTTGTG GGGAGGGGAC AGTTTAATGC CCAGAAGCGG TAAATAAGGA ATCCTCTGGG GAGTGGTAAT GATCTGGATG CTGGCTACAG GATGTGTTGG TTGTAAAAAT GCATTTTTTT ATATCTAGCT TTTTCCATGT GTATATTATA CTTCAAAGAA GTTCAGTTAA TAATTTCTCA TGTCACTGTA GAGTAGCTCA GTTAGCCCCA GCAAGCCTCT GGCTTAATCT TGTTTTACCT TAAGCCATCA GTCATTTACA AGTAGGAAAA TTCACAGGGA AAGTTAGAGT ATAAAATCCA GAATGAAGGT TTACTGGGTA AGAGTCTCTC CATTTTCCAA AGCCCGTTTA TTTCTTGATT CCAGTTCTTA AGAAGTCTCA GCATTGTGTC TTTTTCATGT ATCTTACAAG AAGACAGCAT GTGCTTCTAA CACCTGATAC ATTGTATCTA CCAGCACTTG GTAAACAGAA AAGAACCACA TTTTTCTTGT AGGAGAAATT TGGTGCCTAT TTCCTACCAG GCACCAATAA

GTGGGACCAA TAGGTGGGAT TAAAGATACA GTAGAAAGTA TTTAAAACTT GCCAGGGGGC AATAGTCTGA AAATAAGTAA ATTGGTGCTA TAGAATGGAA GTTACAGGCT TCTTTCTTTT TTCCCACAAG ATCTGCTCCT TGAGCCCCTA GAGACTTTTC TGTCTGTTAC TGTTTCTTCA TTCCTCATCT GCAGAGCCAG CCCTGAGAAG TGCAGACCAA AGCCAGGGAA GGCTCTGCAA AGATGTACAA ATGGAAGTCA CCTTAATAAC CTCTGACTGC TGCGCATAAT ACATTTCACT CAAAAGAGGG GTTAAACAAT GGAACAGAAT ACAGAGGCCA GAAATAATGC TGAACACTGA CAACCATCTG ATCTTTGACA AAATCCACAA AAACAAGCAA TGGAGAAAGG ACTCCCTATT CCATAATGGT GCTGGGATAA CTGTCTAGCT ATATACAGAA GATTGAACCT GGGCCCCTTC CTTACATCAT ATACAAAAAA TAACTCAAGA TGGAGTAAAG ACTTAAATCT AAAACCAAAC ACTATAAAAA

CCCTGGAAGA TAGCCTGGGA AATACCATTC TGGACATAGG ACCTGGCAAA GACTTCATGA CAAGACACCA AAAGCAATAG CAACAAAAAC CAAATTGACT AATGAAACTA ATGAAACTCT TTAGTTGTAC AACAGATAGT TTATCTGTAC AACAAAATAA ACTATCAACA GAGTAAACAA CCTACAGAAT GGAAAAATTT TTTGCAAACT ATGCATCTGA CAAAGGTCTA ATATCCAGAA TCTATAAGGA ATTTAAACAA ATTTACAAGC AAAAAAATGA CCTCATTAAA AAGTGGGCAA AGGACATGAA CAGATGCTTT TCAAAATAAG ACATTCACAC ATCCAACAAC CATATGAAAA GATGTTTAAC ATCACTAATC ATTAGAGGAA TACAAATCAA AAGCATAATA AGATACCATC TAATACCAGT AGGAATGACT ACTATTAAAA AGTCAGACAA TAACAGATGC TGGTGAAGGT TGTGGAGAAA AGGGAATGTT TATGCACTGC TAGTGGGAAT GTAAACTAGT TCAGCCATTG TGGAAGAGAG

TGTGGTGATT CCTCAAAGAA TGTAAAACCG AACTGCCTTT CAATCCAGCA ATCCCATTAT TGGATATACA CCAAAAGGAA TAGAAATTGT TTTACCGTAA AGGCGCATGC ATGCATATGT TCATTACAGC ACTATTTACG ATAGCAAAGA CATGGAATCG TCTAAATGCC CATCAGTGGT AGACTAGCTA AAAAAAAAAA AATGTGGTAC ATATACATCA CAGAATAGTA TGCAGCCATA AAAATGAACA AGATCATCAT GTCCTTTGCA GCAACATGGA TGTAGTTGGA GGCCATTATC CTAAGCAAAT TAATGCAGGA ACAGAAAGCC AAATACCACA TGTTCTCATT TATAAGTGAC AGCTAAATAT TGAGTACACA TGGACACAAA GAAGGGAACA ATAGACATGG GACCTACTTG AGAATAGAGG GTGGGAGGAG GGTGAGGATC AAAAAGTACC CATAGGACAC TGTGCTTATT ACCTGGGTGA TGAAATAATT TGCACACCAA ACCCCTGTGA CACACAATTT ACCTATATAG

AAAACCTGTG CATGTACCCC TGAACCTAAA AGTTAATGGT GGGGGGGTGG GGTTAAGCTA CTTTGTGGTA TAAATCTGAG CATTCATATT AAAATAAAAT ATTTACCTCA TTAGAGTAAT TAACATTTAT TAAGCAAAGA GCCAAGTACC TTACACACAT GATGTTTAAT CTCACAATGA TCTTTAATCT CATAACAACC GTCCATTGTA TGTACATATG TGGAAATTGA GCCTTGGAGA GATTAAATGC ATGGGGCATG CCATTTGACT AGAAACTGGA AGCATCAGGA TTTAAACTCA GTTCTGAATG GTTTTGTAGG CTTTGTTTTT TCCACATTAT AGCATGGCCT GCCATGAAGA ACAGGTCCTT TCTGGTGTTT GTCTTGTTTG GTTTAAGTGA AGCAAATATT TATTTAAATA TTCAAGATAT GCTGTTAAAT TTTTACTCAA AAATTTGAGT ACAGTATGGA TCTTCTGAAG CCAAATAACT CTTATTCAAT GCTTAGTTGA GAAATTTTAT GGAGTAGTTC TCAATTTTTA TGTAGTTCCA

CTGCAAAGGT AAGTCTTATG GAAAGATTCA CTGTAATTTT TTTTCCTCAT TTGGACATCA GCTTTTTCTT TTCCTCAGAC CCGCTGAAAG ATAATTTTTA AAATAAAAAC CTTGTTTTTA TATCAAGTGG GGACATTTTT TCCAAATGAA AACCGTGTAT TCATTTTATA TGATAAAATC AATGTTATTA TTTTTAAAAT TTTGATTTAA AAATCATTAA AAATAAATTT TCAGATATTA CCTGAAATTC TACCATCCAG AGATAATAGT GCTTAAAGAT TTGATATATA GACACACACA CATATATACA TATATATCAT CCTAAACTTC TTTGTATAAA TGTATATAAA GTTTTTAATA AAAACTAGGA GATTAATGCC CTTTGAATGA AAATAAATAC AATGTGTATG CTTTAACATC TTGCCTTTAC TTTATAACAT TTATCACAGC AGTCATGAGA TAATGATTTA CATGGTCATT GTTAGTAAGC TAATAGCTAA GTGCATGAAC TCTGGAGCTA GCCTCCCTGG ATTTTAATCC CAGATCTGTC

ACTGACCAGC TGAGCAATAC TAGGTAAATT GCTCTTGTTC CTTAGTTTCT TCATCTGTAA AATAGAGATA AAAATAATAT CCACCTCATA GGATTGGTGT GAGCATTAAA TGAGCATACG TATGTAGGCC ACTTAACAAC AATGCCTTCA CATACTGAAC ACAAATATAC GAGCTGTTGT CTTATTGGGC TCATGTTTTT CCTACCACTA AGCCGCATGC ATGCAAGGAC CATGTTGGTT TTGTTCCACA TTGCATCCCC AACCTGGTAT ACAGTGTGCA TTCAATAGTT GTTGACTATT ATTACTAGTG GCATTTAACA AATATCTGTT AAATGAGTGA AGAAATACCC ATTTACTGCA AGTGTGTCTA ATATTGATGG CATAATGGGG GAAACTCAAA CTCTGGAGTC AAACAGGTTT TAAAACCTTA TTCCCTCATC CTCAGTTATT GACGTTTTTT TTTTGGCAGG TGTGTGTGTG GGACAACTTA TTGAACTTTT CTGAATTTCC AGCTTCGCAT ATATAAAATA GAGATAGTGA TTCATTCTTG CAATGTATGG ATTTGAGACA ATTGTGTAAG TTTATCAATA AATAGTAGCT ATTTTTGTAT AAGTATTACA TATAATATCC AGGCCACTGC TTTGCATAAC CCAAAAGGGG CACCATTCAT GCAGAATACA ACATAAATGG TGTCCCTGGA GCAGTGCAGT ATAGGAACCC TGAGGGGACC TACAGTATAC TTTATAGTTC ATAGATTACA AATTATCCCT TTATCAGAGT CTCTCAAGGT TGGATGTATT TGAGGTCCAT AAGAGCAATT TAGGATTAAC AGTAGCTGCA GAAACCATCT GCAGTGATAT TCTCATTTTA AATCCGCGGG AAAGAAGACA GCTATAAACT TGGGACCTGG GTTTAAGCAT TTTAAATGCC AAGTTGACCA TTTTCTAAAA CACAACAAAT ACCCAGTGAG AGAGGGAGAA GGGAAGTAAA

TGCCTCTGAA TAAGCAAGTT AATGTCAGTA GTTGTACTGT ATGCATATTG ATGAACAATA GAGGAACCAA TGTCCAATCA GATGAGCAGG ATATTTGGCA ATAACAAGTT GCCTTTGAGG AAAAATGATT TTCTTGGCAA GTTCTTTATC AGCATTACAA AGCTAAAAGC TACGCTTATC ATCACTTATA CTAGCATACC CTGTTGTGCA AATGCTGTCT GTGTTTGCAT CTGCTATTGT TGATGCCTGG TGCATGAATC AGGACTCCAG CCCACAAGTT TTCCCAGAAC TTTCTTATGG CCATCATCTT TAAGTGTCTG GTGAACAGTC ATAGTTTGGT ACACAAAAGG GTCAACCTGG GGGATGGCTA GGGTTTGACT CAGTCGTTAC ATTTCAATAG AGCAGGAAGG GGAAATGGTG GCCTGTAACC TCAGGGAATT TTGCCAGTTG GTCCACCCCA CTCTCTCTCT CCTGCTCTGA GGAAGTGGCA CAGCCTAGAA CAGCACCACA GGTGAGAGAA ATGCAAACCC TAACCAGAGA AGCAGACTCT

TTGCCAGTAG TAATAGTTCA GGACCACCAC CAGCTTTTAT TAAAATTTTT AATAACACTC AAGTATTGGC AGAAAGAAAT AATCTTGGGT TAACTATAAC TAGAATATTG ACTCTTCCTC TGTGGAAGAA TCAGCCAATC ACATTTGTTT ACATCAGTTC CCCTGAAGAA GAAAAATACA CTGATGTTGC AGCAAGACAA ATTTAAGCTA GATGTAAATA ACTTCCTTTA GCCTGTAATG CTAGGCTAAT TACATATTGG AACTATTTTT TCAGGGAAGA ATTGTGTAGG GTTTCAGGGA AGAATTCTGA AGAAAATATA GAGCTGAAAT GATCTTGCAG CTCACTGAAA CTGCAGGGTT TAGATCCACA CTGATACTCG TTCTATTATC ACTGTAATGA AGGCTGATGG AATAAGTAAA AATGTTTTGT ATTAGTATGT TTTTACACTT ATTTGCAAGG CATAAATAGG TTAGGTTTTG ATCTTAATTT AATTCTAACA TGTATTGTGC ACAAGCTGTG AGCAGTTTTC AGGAGTTAGG TATCTGGCCA

TGACTGATTT TTCAGGAGTT AATCATCTGG TAGAAGGGTC ATACACAATA GGAAGATGTG TGTGACAGGT TGTGATCATT ACTATAATCA CACAGAGAGC TGTAGAATTT TAGGCTGGCA GGGTGGCTCA CGCCTGTAAT CCCAGCACTT TGGGAGGCCA AGGCAGGCGG ATCAAGAGGT CAGGAGATGG AGACCATCCT GGCTAACACG GTGAAACCCC GTCTGTACTA AAAATACAAA AAAAAAAAAA AGCCAGGCGT GGTGGTGGGC GCCTGTAGTC CCAGCTACTT GGGAGGCTGA GGCAGGAGAA TGGCGTGAAC CCGGGAGGTG GAGCTTGCAG TGAGCCGAGA TCGCATCACT GCAATCCAAC CTGGGCGACA GAGGGAGACT CAGTCTCAAA AAAAAAAAAA AAAAAAAGTC ATGTTAGATC CAGAGGGGTA GCAACTGGGG CTGGGCTGTC AGTCAACTCA GTCAACTCAG TCAACTCTGC TCCCCCACAG GAGATGCCAG TGATGCATTT

TCATGGCCAA CATTGTCAGT CAGCATCATT GAATTACTCC TGATTATAGA GACACAGCTG CAAACGATTC CCCATTAAAT ATGATGTTTC TTGCAATGTT TGGAAGGTAC TCCTTTTTAG TAAGGGAAAT CCCCTCTTCT GGCTTGCTGA AAGTTTTTTC TTTCCATTTT AAAAATCGTG AATTCCTTTT TGCAATATTG AGGTGGTTAT ATGGTTTCTC TTCTCTAATC TGTTAATATG GTGATTTAAT GGTTAGAAAT TTTCTAATGT AAATTCCACT CATATTGCAG AAATAAACCT AAACTGAGCA TGAGGCTATA TTTTTTATTT GCTTCTATAT TTGGTTGCTA TACAGTATTA TGTTTAAGAT TTGTTCACAT ATATTTGTGA ATGGGATTGG ACTATTTTTC CTTCTTGCCG ATTTTTATCT GGTTTTTAAA TTAAGGATAT TTTAGACTTA TGAAATATTT GGCAAACAAT CCTTGGCAAG TAATTTTTTG GGGAATTTGT TTTGGCTATT TTGAGTATTA CCCAATATAT TTTAATTAAG

TTATTCTTAA TGTTTTCTTA ATTAAAAAAA TTACCTACTC TAGAGATATT CTTTATGTAC TCCAGATTTT GTCTATTTAT ACCACTTTTC TTTTTTCCTC GATGAGTGTC ATAGATGTTC ATCTATTTTT TTATCTTCTT TGATCTTCTC TTATTCCTTG TTTCTATTAA CTTCTGAAGT TTATTATTTT CTTTTTTCCA CTTCCTTATG GTTTATTCTT TCAATTTTTC TCTAACTTCT TAAGTTGGGT GTTTAATTTT TAGCTTGCTT TGCTTTTTTA GGATAAGCAT TAAAACTACA AATTTTCCTT GTTATTCTTT TGCTGCACCC CAAATTGTTG ATATTTCTAT TGTCTAATTT CTATTCAATT AGAATACTTT AAAGTTTCTT TTTGGTTTTT AAAAACTAAC TTTTTAAATT GACAAATAAA AATTGTGTAT ATTTATTGTG CACAGCATAT GGCTTTGAAA TATATGTACA TTGTGGAATG GCTAAATTTA GCTTATTAAT GTATGCATTA TCTCACATAC TTATCATTTT TTGTGGTGAG

AGCTATGTGA CTTTTGAACT TATGAGTTAT TTAAATATTT TTAAATTATT AAGCATATTG GGATTTTAAG TAATTTACCT TTTTATTATT AACTTATAAC AAGTAGAACA GTTAACCTGT ATGATTCTAC ATCATTGAAA TTTATTGACA TTTGCTTCAT AGTCTATTAT ATGGTCTACT TTTGTTCATG TTACATCTGT AGTAGAATTG GCTAATAGTT GAGTAAAGTA CACATATGTC TATGAAATCA AGTGTAATCC AGAGAAAAAG AGAAATTTAC TGAATATATT GTTCTAGGTG CTATTATATG TTGTCATGTT TAATCCTCAC CACAATTGTA TGAGGCAGCC ATAATTAATT CCACTTTACA CATGAGGAGC CTGAGGGTTA AAAAAAAAGC TAGCTCTACT ATTTGTAAAG AATGAAGCAA AGATACAAAT GAAGGCCCAC ATATCCTATA ACTAGATATT TAAGCATTTT AATTCAAGCT TTAAAACTGC TAAATAAAAT GTGCTCCAAT TTCTATATTG ACAGACATAC CTTCCTAATG

AGCTGGGGTT CGAATTTAGA AATCTTTGAT GCTTCAGAGT CCACACTGAA ATGTGGAGGC ACATAGTGAG TTGGTCCCCA GCCTTCAGTC CACCCACCTT CTCTTTACTA AATCACCTTT CACATACATG TATGAACACC CCAGCCTCCA AGTCCAAACC CTAAACAAAA TGGGACACCC TTGTGCATAC ACAGAGACAC AGCCCATCCT CAGGAAAACC TGGAAAAGTC CATACAAGTT CTGGAAGCAA GCTTGGGACG GTTTCAGTAG TGTGGTCTAT AAGGGAGGCC TCAGAAGACA GGTTTTCTTA ATTCTGTGAA CTTCTCCCAC AGTAGAAAGG GTGCTGGAGG AGGGTCAGAG TGAGGACTTC TAAAGCATGG GTCCTGAGTA GGGGCCACTC TTGCCCAAGT CTAAGAAGGG TACTAGAATA GCACACTACT ACTAGATACT AGAACCCAGA TACAAGCACA GGTCTTCTGA AATTAATAAT AATAATAACT ATTACCATTA TTATACCAGT AGCTGTCATT TATTTAGTGC

TTATTATTTG CCAGTCACTG TTCTAAATTC TTTACATGTA TTATACAACT GCCATATAAC TGCCATATGA GGGATGTACC CTCATTGTCA CCATTTTACC GATGAGAAAA CTGGCATAAA ACGTTTAAGT AACTTGTCCA AGTTACAGAG CTTAGTGAAG CCACAATGTT GCTCAATTTG CTCTCAAACT TCAAAGGGAT GGGAAGGACA CCTAAGTCAT AGAGTCTTTA AGAATCAGAG CTAGAAGGAA TCTTAGATGT TATCTAGTCA GCCTCCTCCC ATTACAGTCC AAGAGAAGAT GGCCCTGAGT TACTTGTAGC TATTTTTGCA TGTGAATTGC AAGTGAATAT ACATTCTACT GAAGATAAAA GATATTTAAA GATATCGCTG GATATAGGAA CAGTGGTTTT AAATCTCTAG GCTTTAACTT TTCTCAGAAC AAGAAATCCT TTTTGGTTTT AATCTATATG CACATCTGTA TTTTTCTCAA TTATCGGGTA GTAAAATATA ACTTTTCTTC TGTAATATTT TTTAACTTTA ATGAGTGTTC

CTCATAATAG AAAAGTTTGG AAACCATTGC TATGGGTATA TACTTTCTAA AGGGATAGTA ATTTCTCTAG AATATTCATT TAATGCTCCA GAAGTAATTA GCACAATTGT GCAAGTCTGT GCATCATCAA CTATACATTC TGCCTGTTTA CTCCAAATCC ACATGAAACT GATTATACAG TCAAAGGCGA GCCCAGTGGA GAGGCATTTT TGGAGACTTC CTGGTACATT GAGACAGGGT CGGCCAGTCT GCGTTAGGGT CTTGGTCAAA ACTGCATTTC TGAAACTAAA CTCAGATTGC TTTCTTTTAA GGGGTCAGAA CTGATTCAAA TCTACATTTT TAAAAGCCTT AGATGTGGGG CTTTTCCTAT TCCCAGTCTC CGCTATTGGT CTTTGTGAAT CCACAGGCAA TTTGGCCACA TCCTTGACTC TCTCTTATAT TAAGAATTAA ACAGCTAAGT TCATGCAGAG GAAATATAAC AAAGGAGGGA CTTTCCTACA AGATCTTTGA AAAATGGAAC ATTTGCATAA GTCATATTTA GCCAGAACTG

TTGTTTTATA TTTTCCTTTC TGAATACTTT GTTACACCTC CTCCCAGCCA ACCCCCCCCC TCCCTGACCC CAACTAGTCA GAGACCAAAG CCTTCACAAT GGTTTACACT TGAACCTTCC TGGCCCCACC CTCATCATCA CGCCTGAATA ATTACATTCA CTGACTGGTC TCCCCTGCTT CCGTTTATCT CCACTCCTAA ACCCTCTGAC ACCTTAATCT TCCCAGAATA CCATTGTGAT CCTGTTCCAC TCTTGCTCAA GTTTTCCCAG AAACTAGAGT ACAAACTTTA TAAGCTTTAG AGTTGAAAGC CACTCTATCT CTTTTTCATC CCCAGGTCTC TGCCAAGGCA GTATAACCTG TCCAACATCT CTAACTTCAA TACCTTTGTC TTAGATACTA GACTCTCCTC CTGGTTTCTA ATTAAACCTG ATCTAGGATC TAATTTTGCC TCTGAATTCT GTTGCCCTTT GCCAAGTGAT CTCTTCCTCC TCTGAGCCGC AGCATCTCTG AGCTTGCACA CTTAGCATAG CCATAGCACA CACAGCCTTA

GCTTGCAGTT CAGGGTGTTT ACCTTCCCTC CCCTTCCAGA TGCTGGATCC CCAGGGATAG GAACTCTGCC CTTATGTGTC CATAGCCCCT GGTAGTATGT CTTGCAGTCG TACATTTTCA GCAAATGTTT AATTGGTTAA TTGAAGACAA CTGTCCCATG CCTTAAGCCT CTCTTTTTGC TAAACATGCC TGTGTCCTTT GTCATTGAAC AACTATTTTG ATCTATTTTC TTCCTGACAT AGGGGTCAGT TCCGAGGATG CTGAAATCAA GAGACATAGC TTATTCTCTC AAAATTGCTT TCAAGAGTGA TTTTGTTGTG AATTGAGAAC TGGCTGCCTA CTTTTGGACT ACCCACTTCA GCAAGAGTGT TTGAAACCAA ATCTATTCTA AGTAATTTTT TATTCCCTTT TCTCTATGGC ATTAGACACA CAGCTCTTTT AAACTACCTT TCGTTATCTA TTAAACAGAC ATTCAGTAAC TCTATAGACA CTGTCTAGCT ATATGAACTT AGACAAACTA ATATCTCTGA GCTTCAGTTT CTTAAAATTT

AAAATGAGGA CAATACCATC TATGGCCGGG GATTAAATGC TATGAGGAAT GTAAACCAGA TGTCAGGTAC CATCTCTCTA AAATCCAGAT AAAATGAATT AAAAATACTG GCCGCAAACC CTCTCTAAGA GTTCTCAAAA TTCTCAGAGA GCTTAATTTT CATGCTCACC ATAGCACCGA TTTTCTTCTA AATATTTTGT TTCTACCAAA ATATTTTGTC CCAATTTTGC CTTTTATGGC TATTTCTTCA TATCCACTTT CCCAAACTAA AGAAGCAGCC CCTTCACCTT AAACTCCTCC TTCAAAGCAA CCTAAATACA GGTCTGGGTT TGTATTCCTA GTGGGATGTT ACAGAGGTTA GTGTGATGCA GAGGAGGAGT CATGCTGTTT AAATCCATAC TAGTCCCCAG AGGCCAGGCT GCTTCTGCCA CCCCTACCCC TCCCGCCACA GAGCTCTTCA GCTTCTCACA TTTCTAGTTC TTCTCTCTCT ACTTTCATTA CCTTCTCTCT _{ττττττττττ} CTTCTCATGT GCTCACGGGA GCAGAGAAAA

TTAACTCCTC TAAGTTTTCT TAACACAGAG TGCCTTAATT ACATATTACT ATTGTTTGAG TTCCTGCCAA CACTACGTCT GTAGGGTCAC ACCTGCTATA TTAGAGGCTT ATCAAAAAAA GATAGCTTTC TCCTAAAAAG GGATTTGGAT GCCTACTAAG ATAACTGGAT GCCAAGATAA GTTTAACCTA ACAAACTTTA TTATTATTAT TATTATTATT ATTAGAGATA GGTACTTATT CTGTCACCCA GACTGCAGTG CAGGGATGCA ATAATAGCTC ACTGCAGCCT CAAAGTCCTG AGTTCATGCA ATCCTTCTGC TTCAGCTCCC TGAGTAGCTA GGACTACAGG CATATGCTAC TCTGCCCAGC TACTTTTAAA AAAATAATTA GGGATGGGGT CTTGTTGTAT TGCCCAGGCT CGTCTCAAAC TTCTGGTTTC AAGCAATCCT CCTGCCTTTT ACCTCCCTAA TTGTTGGAGT TACAGGCATG AGCCACAGCA CTCAACCAAG ATTTAAAAAC TTTTAAAAGA AATCACATTA CTTACTGTTA

TCATCATTAT GGTTACTACC AGTGTTAAAA CAATTGGTAT TGAAAACACC ACTACCAGAT CAAGGTTCAA ACCAAGATGT CAAGTAAATA TTATTGTCAG ACCTCTGAGC CCAAGCCTGC AGGTATACAC CCAGATGGCC TGAAGCAAGT GAAGAATCAC AAAAGAACTG AAAATGGCCG GTTCCTGCCT TAACTGATGA CATTCCACCA TTGTGATTTG TTCCTGCCCC ACCTTGACTG AGGGATTAAC CTTGTGAAAT TCCTTCCCCT GGCTCAGAAG CTCCCCGACT GAGTACCTTG TGACCCCCAC CCCTGCCCAC AAGTGAAAAA CCCCCTTTGA CTGTAATTTT CCACTACCCA CCCAAATCCT ATAAAACAGC CTCACCCCTA TCTCCCTTCG CTGACTCTCT TTTCAGACTC AACCTGCCTG CACCTAGGTG ATTCAAAAGC TTTATTGCTC ACACAAAGCC TGTTTGGTGG TCTCTTCACA CAGACCATGT GACATTTGGT GCCGTAACTC AGATCGGGGA ACCTCCCTTG GGAGATCAGT

CCCCTGTCAT CCTGCTCTTT GCTCCATGAG AAAGATCCAC CTATGACCTC TGGTCCTCAG ACCAACCAGC CCAAGGAACA TCTCACCAAT TTTAAATTGG GTAAGTGGCC TCTTTTTACT CTCTTCTCCA GCCTCTCTCA CTATCCCTCA ACATCTTTCT CCTTTCAATC TTGGCACCAC GCTTCAATCT CTCCCTTCCC TTAATTTCAG TTCCTTTCTT TTTCTGGTAG AGACAGAGGA AACGTGTTCT ATCTGTGAAC CCAAAACTCC AGCACTGGTC ATGGACTTGG AAAGACAGTC TTCCCTTGAT GTTTAATCAC TGCAGGGATG CCTGCCTGAT TATTCACCCA CATTTCAGAG CTGTCTGATC ACTGCAGGGA CGCCTGCCTG GATCCTTCAC CTTAGTGGCA AGTACCACTT TGCCTGGGTG GCAAGCACCA CCTCTCCTGG GGGGCAAGCA CCACCTCTCC TGGGGGGCAA GTACCCCCCA ACCCCTTCTC TCCATGTCTC CACCCTCTCT TCTCTGGGCT TGCCTCCTTC ACTATGGGCC

ACCTTCCACC CTCCATTCCT CCCTTTTCTC CCTTAGCCTG TGTTCTCAAG AACTTAAAAC CTCTTCAACT CACGTCTGAC CTAAAACCTA AATGCCTTAC TTTCTTCTGC AATACCGCTT GACCCCAATA CAAACTCAAC AATGGTTCCA AATAGCCTGA AAACGGCACT TTCAATTTCT CCATCCCACA AGATCTAAAT AATTCTTGTC GTAAAATGGA CAAATGGTCT GAGGTGCCTG ACATCTGGGC ATTCTTTTAC ACGTCGGTCC CTCCCTAGTC TCTGTTCCCA ATGCAACTCA TCCCAAATCC TCCTTCTTTC CCTCCTGCCT GTCCCCTCAG TCCCAACCCC AAGTGTCGCT GAGTCTTTCC AATCTTCCTT TTCTACTGAC CCATCTGACC TCTCCCCTCT TCCCCAGACT GCTCCTCCTC AGGTCGCTCC CCGCCAGGCT GAATCAGGCT CCAATTCTTC CTCAGCGTCC GCTCCTCCAC CCTATAATCC TTCTATCACC TCCCCTCCTC ACACCTGGTC CAGCTTACAG TTTCATTCTG

TGACTAGCCC TCCCCCACCT GCCCAACAAT TTCCTCTTAA AGAGGTGGCT GGAGCTAAAG GCATAGTCAA GGTTAATGCT CCTTTTTCTT TATCCAACCT CTCCCATCTC AGTTAGTATT TAGGCTTTTT TTCATCAAAT ATGAATACCT AGCCCACTCC ATGGCTCATT TGGCAGCAAC TCCTAGACAT TTTACAGCCT TGGACCCAGA GGGGCCAGAA GGTCATCTTA TTCTCAATAT GCATTTTATT ACCCAATCCA CTCCCAACAT TAGAAAAAGC TCCAAAAGTT AGACTCCGGC CCTCAAACCC CACAACAGGA CTTAATTAAC CTTGCCTTCA AAGCGTACAA TAATAGAGTA GAGGCAGCCA AGTAGCAACA TATTTCTGAG TTGCAATTCC TTGCCTCCAC TGTGAGAGAA ACCCCAGCCA CATCTCCAGT ACACAAGAAC TTCAAAATGC CTAAGCCACA GTGGTCAAGC ATTCCTACAG GACCTCCTCC ATCAGGATCT TGCTTCAAGT GCCAGAAATC TGGCCACTGG GCCAAGGAAT

GCCCTCAGCC TGGGATTCCT CCTAAGCCAT GTTCCATCTG TGTGGGACCC CACTGGAAAT CGGACTGTCC AACTTGCCCA GCACCCACTC CCAGAGCCCC TGGAACTCTG GCCCAAGGCT CTCTGACTGA CTCCTTCCCA GATCTTCTTG GCTTAGTGGC TGAAGACTGA TGCTGCCTGA TCGCCTCAGA AGCCTCCTGG ACCATCACAG ATGCTTTTGG TAACTCTTAC AGTGGAGGGT AAGTCCGTCC CCTTCTTAAT CAATGCAGAG GCTACCCACT CCACATTACC TTCTCTTCAA GGTCCTGTTT CCCTTGTCTT CATAAATGTT GTGGGTATTG ATGGCCAGGC TTCTAAACCC CTTAAAACTC CCCAACTCTG GTGCCGATTT AAACAACATT CTTTTA ACA CTTCTTTTTA GTTATCCCCA CCTGCCCAGT TCCCTTATTA GGCTGAGACA TTTTAACCAA ATTATTTGCT TCCCTGACTA TTCCTGGACT ACAGCCACAT CTCATTGCTG CCCTTCTTCC CAACCCAAAA GTGGCAACTC

CTTTGCCACT TCCTCTCATA TCCCCCTACC TTAACCCACA GGTATGGGAC ACCTCTACTC CCTCCCTGGC AACAAATCAC ACCCTCATTA CTATCCCATT AAAACCTAAT CACCCTTACC TGGGTCAACG CCAGTATCCC ATCCCACAAC AGGCTTTAAA GGGATTAAAG CCTGTTATCA CTTGCCTGTT ACAACATGTC CTTTTAAAGC CTGTAAACTC TCCTTACAAT TCCCCCATTT TACCTGTCCA AAAACTGGAC ATGCCTTACA GGTTAGTTCA GGATCTGTGC CTTATCAACC AAATTGTCTT GCCTATCCAC GCCATGGTGC CAAACCCATA TACTCTCCTA TCCTCAATAC CTCCCTCCAA AACCCCTCCA TAACCCTTAT TCTGTTCTGG ATCTCAAAAC ATGCTTTCTT TACTATTCAT TTGCACCCTT CATCCCAGCC TCTCTTCACT TTCACTTGGA CTGAGCCTGA CACCCATCAG CCTCAGCAAC TTACCTGGGC TGTACTGCCG CAAGGCTTCA TGGACAGCCC CCATTACCTC AGTCAACCCA AATTTCTTCT TCATCCATTA CCTATCCAGG CATAGTTCTT CATGAAAACA CACGTGCTCT CCCTGCTGAT CATGTCCAGC TAATCTCCCC AACCCCAGGA CTGGCAAATT GACTTTACTC ACATGCCCCA AATCAGGACA CTAAAGTACC TCTTGGTCTG GGTAGACACT TTCACTGGAT AGGTAGATGC CTTTCCCACA GGGCCTAAGA AGGCCACCGT GGTCATTTCT TCCCTTCTGT CAGACATAAT TCCTTGGTTT GGCCTTCCCA CCTCTATACA GTCTGATAAT GGACAAGCCT TTACTAGTCA AAGCACGCAA GCAGTTTCTC AGGCTCTTGG TATTCAGTGA AACCTTCATA CCCCTTACCG TCCTCAATCC TTAGGAAAGG TAGAACTGAT TAATGGTCTT TTAAAAACAC ACCTCACCAA

GCTCAGCCTC CAACTTAAAA AGGACTGGAC AGTACTTTTA CCACTTGCCA TTCTCAGAAT TCGGGCCTGT CCTCGAAATG CTACAAGGTA CAGCCCATTT AAGATTCTGT ATGGACGCTC CTTTTTATTA GGCCCCAGTC TCATTCCAGA CACCAGCCCA ACTTGAACTG TGCCCCAAAA ACTTGTCATC CCTACAATCT TCTGTCTAGT CATACTCCTA TTCACCATTC TCAACTACTT GTAAATGCCC TGCCCTTTTT TACAGTGCTG ATTTATACTT TTCCTCCAAA CCATCATAAC TGATATCTCC TGGTTTTACC TCAAACCGCC ACCCTTAAGT CTCTCTTAAA GTGGATAGAA GATCTTCAGT GACAAGGTAC ACTCCAATAC TTTCACCCTA ATAAAGCCCT ATTCTTTACT TTTATATTCA CTCTTATTCT TGTTCCCATT CTTATGCCAC TCTCTACCTC TCCCCAGCTA TCTCCACCAC ACTATCAATC TCACTCACTC TCTCCTAGCC ATTTCTAATC CTTCTTTAAC AAACAATTGC

TGGCTTTACA ATTTCTCTTT CCTCCAAAAT CACCGAGTCC TCAATTTACT CACTGCTAAA AAAGGGGACT CTGCATATTT TTAAATGAAG AGTGTTGTTT TTACCTAAAT CAATCTGGCC TGGTATATGA CAACATAAAA AAAACTCAAG GATAGAGCCA AAAACCTTGC CAACCAAGCA AGTAATTATG CTGAACCCCC TTGGGCACTC TAATTAGATG TCCTGGGTTC TCCCGATTCT TAATCCTTTA ATACCTGTTT TTCTCCTTCT CTTATGCAGA CCTTGTGTCT TCCATTTAGT TTCTCAATTC ATACAAAACC GTATCCAGGC CATCACCAAT CATTCTATAC GACAAATGTT TTAAGGGAGG AGACCACCCC TCATATTGTC TTATGCCCAA TTTCTGCCTC CAAAGAAAGA AGTAAAAATG AAAAGGCAGA AATGAAATCC ACAGGCAGAC AGCCTGATGC CACACCCTGG GCCTGGTGGT TAAGATCAAC CCCTGACCTA ATCAGTTATG TTATCTATAG ATTACAGACA TTGTATGGAA

AAGCACTGTG AAAATCCCTG TCTTGTTCTG TTCCTCTAAT TACCAGTACA CGCAGCCCCT AGTCATGTAC CCCCTGCTTG CTCCCCCTGC TTGCTCAATC AGTCATGACC CTCTCACGCA GACCCCCTTA GAGTTGTAAG CCCTTAAGAG GAAAAGGAAT TGTTCACTCG GAGAGCTCGG TTTTTGAGAC ATGAGTCTTG CCAATGCTCC CAGCTGAATA AAGCCCTTCC TTCTTTAACT CAGTGTCTGA GGGGTTTTGT CTGTGTCTTG TCCTGCTACA GTTTCATCTA ACAACCCCAT AATATCACCC CTTACCACAA AATCTTCCTT CAGCTTAATC TCTCCCACTC TAGGTTCTCA CGCCACCCCT AATCCTGCTC GAAGCAGCCC TGAGAAACAT CGCCCGTTAT CTCTCCACAC CACCCCCAAA AATTTTCACT GCCCCAACAC TTTACCACTA TTTCGTTTTA TTTTTCTTAT TAATATAAGA AGATAGAAAT GTCAGGCCTC TGAGCCCAAG CCTGCACGTA TACATCCACA TGGCCTGAAG

CAAGTGAAGA ATCACAAAAG AAGTGAAAAT GGCTGGTTCC TGCCTTAACT GATGATATTC CACCATTGTG ATTTGTTCCT GCGCCACCTT GACTGAGGGA TTAACCTTGT GAAATTCCTT CCCCTGGCTC AGAAGCTCCC CCACTGAGCA CCTTGTGACC CCCACCCCTA CCCACAAGTG AAAAACCCCC TTTGACTGTA ATTTTCCACT ACCCACCCAA ATCCTATAAA ACAGCCCCAC CCCATCTCCC TTTGCTGACT CTATTTTTGG ACTCAGCCCA CCTGCACCCA GGTGATTCAA AAGCTTCATT GCTCACACAA AGCCTGTTTG GTGGTCTCTT CACACCGACA CGCGTGATAA TTATTATATT ACTTTTAACT AAAACCCTTT CAGAGTCTCG CAGGGAAGGC TGTATATATC TCATAAAATG TTGGGGCCCA CTGGATCAGA CAAGGCCACA AAGGCCAAAG GGAAGTAAAG ATCTCATTAT TTCTCCTAAT AATTTCCCTG TCCTTTGTCA TAAATGGTGG GTAGGCTGTT ATGGTGATGG

CAGATTTTCT TTCCATAAAA TGTCCATAAT AGGACATTTG AACAGAAGGG AAAAATCAAA TTGCTGAAGT TGAAAGAGGG CAATGCAAAG AACTTTGGAG AAAGAACTGT ACAGAGAAGT CAACTGGCAG ATGGGAGGAA GTTTAAGGGG AAAAATATAG ATGTCTAAAG AATACATTTA TTCATTTTCC ACAGTGCAAT TTGGACAAGA AGCCTCTTTC TTGCTTCTTT CTATTCTCAT TAAATCATTA GAGCTCAAGC AATCCTTCTG CCTCAGCTTC CCGACTAGCT AGGACTACAG GTATGTGCTA CTATGCCCAG CTAATTTTTT AAAAATTAGA TTTTAATTTG GTGAACTATT TCTGTAGGAA ACTACAATAA TACAGCCCAG GCACATTGAT CTTGGGTGAA CAAATCAGAA GGAATGAATA ATTCTGTGTT CCTGGGACTC TGAC AATTTC ATGAACTTGG T ACTCTGAGT AAAGC ATAGG AGGAGTT ATT TCATAAAATG TGGAGCAC AA TC ATGTGACA AAGAT AATGG GATCCCC ATT

TCATAAATAA ATCTGAAGTT CAGAGAGAGT AACAACTGGC CAGGGTCACA TCACGGAGAC AGAGGCAGGG TTCCCACTGA TGCCTCTGAC TCCCTGTCCC AGGCCCTTCC TCCTCCCGCA AGCAGAAGTG CAGGGGGCAG AGCTGACCCT GTGCAGTGAA AATCTGAGGG CTGAGTTCCT ATTGGAACAC AAGTGAAAGA CTTCCTGGCT TCTAATCTCA GGATAAGGAC TCAGAGCTCC ATCTGTTCCA GCCTTAGGAT AAGAACCAGA ATCTTACACC ATGAAAGCAT GAAAGGTAAG ATTTGAGTGA GGAAAAAAAA AAAAAAAGTC TGTGTTTCAG ATTCAGTTCA CAAAGCAGTT TCATACTTAA GGTACCATCA CAATAACCCT GTGGGGTAAG CAAGGCAAAT TTCATTCTTG TTTTATGGGC ATAGGAAGTA AGTCTCAGGG AGGTTAAGAC CAAGGTTTCT GGAGAATTTT ATATTATGAA TCTTGATTTA TGGGATTACT ATTATGTAAT TCCTAAGATC ATATAGGAAT

CCTAGAGCTT GAATATAGAA CTTTATTTTT AAATCTATAT ACATCATAAT TACAAGGAGT AGTGTCCATT TGGGTTCCTT GGCCCTGATG TGTTAGTGGA ATAAACATTT TTGTCAGGGT TGCCATGTGT GTCTGTGCAC GTGTGCACTG TACACCTCCA GGGGATGTAC CCTAAACCAC ATGAATGTGA TTTGCACATC CAAGATTTAC AGTGTACTAT AGGGAGAATC TTTTGCAACA GCTTTTGCTA TAATACAGAA TCTGAGATGT CTTTGAGAAA GAAAAGTGTA ATCATTACCA AAAAATTATT CTCATAATGT GTGCAAATTT GTATGAAATC TATATTGGCC ATGGGACAAG GAGGTATTTC CAGCTAGCTT CTGAAAGGGC TCTATTCTCT CATAAGAATT CAGCTGTTGA CATTAGGTGA TATCTGCCCA GGTCATCAGA TGCCATAGAG AAAGAGGGTT TGCTGAAACT TATATCAGCA GTGCACTGTA TGCTCTTTCT GATTTATTTG AACATTCATT TATTGAGTGT CAAGTAATGC

ACTAGATACT CCAGGGATCT GACACAAACT CTGCCCTGAA GGAGCATGTA ATCTCACTGG GGAGAAAACA AAACATATGA TAATTTCAAA ATAACAAACT AGGCAAACTA GTTAAGACTT AAAAAGCAGG CTTTATTCAA ATGCAAAATT GCATGTTACA GGGTAACCTT TCAGTAAGAA GCCAGGAAGA GGAGCTCATC ATGGGTTGGA TTAGTAAAGG ACTAGTTATA AAAGAAGTGG TGGGGTTGAG GGAGGCCTGA GATGAAATTT AAAGAATATG TAGAATCTAG GTAAGTGGAT AAAAGGTCTG GGGGCAGGGG AAAGGAGAGC ATTTCATTGT GAATCAAGGA ATTTCTCCAC CTGTTTTAAC TCTTCCATAT GACATCAAAG AGATGTCACT TGCAGCTAGC ATTTCAGTGA TGTTTTCTTA CTAATAATAT CGTGATAAAA GAAACATTGA CTATAAGAAA TAGGAATGGG TCTCATAAAA GGAAACAGCA AAACCCCCAA ACTAAAAAAC AGCGCAGGCT ATTTCTCTCT

TCTCTCCTTT TGCTTGGCAC TCATGAGATG CTAGGTGTGG AAGTCAGCCA ACTGAAAAAG AGAGGTGGCT GAAGAAGGTG GGGAGGCTGA AGCCAGTTAA ATAGGATGGT CCAATTCACA GACGGCGAGG CTACAGTGCA AATAGGACTC TTTCAACTTG AGCAGGACCC CATTACTTCA CTGGAGTTAG AAAGAAAGGA GAGCGTAGAC TTTTTGAACT TTCTATAAGA GTGTACCTCC ACAGTATACA GAAGACGACG TGAAATTTGA TCTGCAAGAA AACTGAGTCC ATATTCACAT ATGTATCAAA TTTGCACTTC ATTTAGAAGT GTCTGTCATC AAGTACAGCA CTGAATTGAA ACTGAAAACA AGAGTCAAGA AAGAGCAAAG TCAGCCATCT TTATATTCCA CATGAATCCT TTCCCTTTAT GGTCTTATTT GTTTCTCCTC AGAAAAGACA AAAAGCTGAG CTGTATAAAC ACCTGTGGGC TGGGGGTTGA GGGATAAATG AGGGGCGAAA TGGAAGCTGA AGGAACTGTT

GGTCAGGTAG AAATCTTCCC AGATGCACTG AAGGAAACAC ACTTCATGTT TGACGTAGGA GGTGCCACCA CACAAAACGT TTCATGGAAG GATTTAAAGG ATCTCATGAT TTTTAGTATT CCAAGAATTT TCTTTCACCA AGGGCGATTT AATATGGGTC ATTCATACTG AAAGAAAAAC AAAAGATAAT AAGAGTTTAA AAATTGCAAA ACTTGGAGTG TTAGTAGTAA AGGTAAATAT TCATTAGAGA TGAGAAGAGG AGCAAGGAAA TGCTTTCAGC TGGAAATCTC AGACAAGAGG CCAGGCTTTA GGAACCTCTG AAGATGAACA AATGTAAGCA AACCCTAGTA GCAGCACTTC TCAGATTTTC ATGTGCTTAC CACTCAGAGA TGGTGTTAAA ATGCAGACTC TGATTCAGTA GGTCTGAGTG GAGCCTGAGA TTCTGCACCC CTAACAAGCT CTTTAGTGAT GCTTATGCCA CTGGCGCACA GACCCCACTT GGAGAAATTT TTGTGGTGCA TACGGTCTTT GTCTCCAGAT

CTAATGAGTC TGAAGGACAG TGTAGATTGA TTTTTTAAAT TTATGTTTAT TTTAATTTAA TTTAATTTAA TTTATTTATT TATTTATTTT TGAGATGGAG TCTCACTCTG TTGCCCAGTC CGGAGTGCAG TGGCACGGAG GCAGCTCATG CAACCACGGC CTCCTGGGTT CAAGCGATTC TTCCGCCTCA ACTTCCTGAG TAGCTGGGAA TACAGGCACG TGCCAGCACA CCCAGCTAAT TTTTGTATTT TTAGTAGAGA TGGGGTTTCA CCACATTGGC CAAGCTAATC TCAAACTCCT GACCTCATGA TCCACCTGCC ACGGCCTCCG AAAGTGCTGG GATTACAGGC GTGAGCCACC GAGCCCAGCT GTAGATTGAT TTTGAGCAGT GGAAAGTCAA GGAATTAGAA GGCATGCTTA AATGGAAAGT GAAATTGGAG AAAATTTAAA CTCATGAAAT AGTGGTGGTT ATAAACTCGT GATAAATTAT ATCCTGGGAT ATAATTTAAT GAGATGGTAA CACATTTAGT TTAAAGAAAT

AAGTGACACT TTTTTTGTGT GACACAACTG TCTTATTCTT GGAAAGGACA AGGAGAGAAT GAAATATGGT ATGTCTTCAC AGCACCTTTC AAAGGGAGAA CCAGATTCTG AGGAGCTGGT CTCATGATGA ACTGTCAGGG TAAACCACAG TTCAGCAGCT GCAAATGTGC TTGCCAAAAT AGAGACAAAA AAATGTTTCT GAAAACAAAA TTTCACATAT GCCCTCCTCT GAGGTTGGCA TCATATCTTC CTGTGTATCT TGGGTGTAGC TTCTATCCTG CCAGAATTTA GACAGTAGAA ACCAAATGAG GTGATAAACA GAGTCATTTT GCAGAAGAGT CAAAATAACC CAGCAAGAAA TGAAACCACA AATGCCCAAG GAGTCATTCA TTCACCATTC AAAAGCTAAT AGAAATGAAC ACAAACTACT ATGAAAATTC ACCCAAGAAC TTAAAAAAAA AAAAAAAGGC TCATGGTGTT TAGTGTGATA GTATTCATTT TACCTTTGAC TTGTTCTAAA AACACACCAT ACTTCTACCC CACCCTTCCT

CAGTGCCGTC ACACAATGGT TTCAGTGTGA AAAAAAAAAC CACGTTACTG GAAAAGGAGG GTGCCTGGGA CTTGCCACTC TAAGCTGGTA GTCAAGGGTC TTGAGTTCTA AAAGCATACG CGTTAAGAGC ATGATTCCTG GATCCAAATG AGTATGGATC TCAGCATTGC CATTTATTGT GACCTCAGGC TATTTTATTT CTCTGTGCCT GTTTCTTTAT CAGTAATGAA GATGTTCATA GACCCTTCTC CCACAGACTT AAAGGCATAT TTCATGATTT AAGACATGTA AACCATTCAT AACAGTATAC AACATGGAAT TAATATTTGA TAAAGGTTTA TGATTATTGT AACTAACTCT GTCACTTGCT CAAGGCCTAT AGAAAACTTA CTTAATTAGT TCAACTACAA AAAGAGTTTG AATGTGATAT CCACCAAGAT CATATTCAGA CCTAGAATTC TGTGATTCTT ATGAATTAAT ACAGCCTTGG TCAATAAATG AGAGCTGGGC AAATAATTCT TCTTTGCTAG GCCTTTCTAG ACCATCTGGT

GAAGCATTCA AGACTTATGT TATTGGGGCC AGCCTTCCTT TCCAACTTCA ACTCCACAAC TCCTCAATAA GCCATGGGCT CAAGAAAGTT CTGCTCAGTG GCCCCTGAAA AATGCTTTCA TAGTCTCACT ACCATACCAC TGCTTACACA ATTTCCTTCC TACAGACTGC CTTCCTTTCC TGCTTTTCTC CATATACCTA AATCCTATCT ATTCTTCATA AGCAACCTTC TTTATAACAT TTTCTATAAC CACCAAGCCA AATGACCTTT TCCTTCTTAA ATATAGCACC CATTGGCCAT TACCATGCTC TGCCTTGTAT TTTTCTGATT TTTTTCTTTC TATATTCCTG TCTTAACTCC CCAGCTAGGT AATAATTTTC CTGAAATCAG GGACCAGGCT GACTCCTCTT GCTGTCTCAA GAAAGCTTAG CAGTTTCCAA CACAAAAATG TTCAATAAAC AACTATTAAT TGACTGATTA TAAAAAATCA GTGAACCATT AAACTTAATA TAGCAATTTG CTTAGCATGG TAATTAGCTT TTTGCTAATA

TTCTTCCAGC CAGTCTCTCC TCCTGTGCCT CAAGGACATC TTAAAAAAAA AAAATCTAGT TGATCTGCTT CCATCTAGTG GCAATTAAAA CAGGTGGTTC CGGTAGCCAG AAAACAGCTC TGGGTAGATT GTGCCAGAAA ATACTTTCAC TCAGTAGGTG CGAGTTTGAA AGAAATCTTC ACATCTGTGG GTTTCCTGCC ACAGACATAG GGAGACCAGC CCAGAGAAAG AAGCCTTTCC TCACTAGACT CCATTTGCAC TAGTAAAGAG AAGACAGAGT AATTAAAAAG AATAAAAAGA ACCTCCACTG ATCGTACATC CTCATCCAGT TACCCCTGCC CCACTTCTCC TTCACAGCCA AACATTTTAA AAGAGATGAC TGCTTGTTCT GTCTCTACTT TCTCATCCTC AGTAATGCTC AATGCTTGGC CGTCTGACCT CTGTCTTGAT GTCTGCACTG CAAATAGTCT CCCCACTGAC ACCCTTGTTG CATCCAGGGG ATACTTACTG GTTCTCTTGG CAATGTTTGA AACCGTTCCC CTTTCTTTGT

TTCCTTGGCA TTCATTACCC CACACTCTTT CTCCTCTTCC TTCTCCCTGC CTGGCAACAT CTTTTCATTT CTCTTTCCCT TAGGTGACTT ATTAGATAAT GATGTTCCTC TGGCTCCCAT ACTCTCTCCC AGGTCCTCTT CCATTCTTAA AGCACTCACA CCCTCCCTGG ATGATAGTAC CCACTCCTGA GATGGCAGTT ACCTCCTGAA ATGTGAGGGA CCCAAATCCA CTTCTCCTGC CATAGCCTCT GTGCTTTGGA TAGGTCCAAT GAGCCACAGT GAATGATGTG CATACACCCA AAGCTCAGTA CAAAACTGAA CCCATGATCT TTACCTCCAA AACCTCTCAT TCTTTTATGT TCCCTTCTCA GAAGTAAACA GGACTACCAT CCGCCAGTTT CCAGGTGAGA AAGATGATAA TTTGATTCTT CTCTCTCACT TTTAGCCAAT TAACAGACAC ATTCAGTTAA TATCACCTCC TCTTATTTCA TGAACCCATT CTTACTACTA GTTCCCTAGA CAGGCGCCAT CGGTTTTAAT CTAATAACTG

CAAATGCCTC CAAAACAAGT CTCTTTGAAT CCAGGCTCAC CTGTCTCCCA CACTTGCCAT ACTGCTCTGC AGGGTGACCT TATAAGATGC CAGAGGTAAG GCTACTCACT GTTTAAACCC CTTTAGTGAT ATCCCAAAAG ACCTCAAGAT AAAGCCCATA TCACATGGCT TATACATTAG TTTATGATCT GGCTTCTGGT GCCTCATTTT TCCCCACTTT TTCCTTTGCA TTCTAAGCAA TGGCCCATAC TAAGTTTGTG ATTGGTAGGA TGGTTGCCCA AACCAGCATC CAATCCCTTC AGAAATCATC TCACTTCATT TCTAGCATTT TAAAGGAAGC TCAGTTGTCC AGCTGGGTAC TGAATATGTC ACCAAAGTCC TCCTTTCATA GTTTATTTTA CTTAAACTCT CCTTCCTAAA ATTCCAGAGC AAGTCACTAA ACCCTAGATA CTGAGAAATA TTTTTCCATC TTCATTTCTG CCAGGTGGGC CATCAACTTT CACATGTCTG CATCTCCTCC CACTGTGCTA TTTCTCCAGT AGAAGAAATT

TGAGCTTCAA GACCAAACTG AAAAATACTT GCCTCCTTGG GGAAGCTGTA GGTAGAATTC ATGCTCCCTA TCTTTCCCAC ATTTCTGAAG GACAATGCCT GTTAGAGCAA TTGAATGCAA ATAGTCAATT GAATAAGCAT TTATTCATTT CTCAATAAGT GCTTGTTCAA TTGAATATTT CTTAAATAAT ATATTTAAGA ACAAGAAGAA CACACCACAA TGTTTTTAAC CCTCAGAAAA AATTCTGAGG TAATCAGAAA AATCTCCCTT TACATAAACT GCCCTTTTCT AATAGGGATT ACTTGTTCGT TCATTCATTC ATTCAGCTCC ACTAGCACCA AAAAGCACAG CTCTGAAAGG AAGCTAGTAG ATTTATCACC TTATCTGGTC ATTTGGATGA GGACCCCAGG TAAATAAACT ACTATGGGGT TAATGTGTCT AGCTAGAGCA GGAAGTAACT TAAGGAAGTA GAGAATGAAT CAGCAGATGT GGAAACTCCT CGCCACTAAT AAAACTTACC TTCTCTTGGA TTTCTTGCCT GAAAATAGAA

AATAGAGAAA AGGCATTAGC AAAAATTAGA CAATTTAAAG TTTTTCAAGT AAGGGAGAAG GAAGACTCCC ACTCTCAAAA CTGTCTTTTG AAGTATATTA GGTATTTGTT AGGTGGACCC TATCTGTGTC AAAGGAGATT TGAGGAACTG GCTTAATAAA CAGTGGTAGA CACTAATACA GAACAGACAT GTTGATGCAG ATGCCTCCTG AGGTTCCATT CCATTCTCCG TGCTACTCAA GAAGACAGAA 25441 TTGCTAAATT GCCTGGTGGC AAGACCCAAT ATGTCCATTC AAGTGTTTAT CCCTTCCCAA TCTGCCATCT CATCCTACCT GCAGATTCTT CCCTTGAGGG ACAGCTGCTA ATACTGTAAA ACTATGTGCC ATTACAGCTC ACAGCATCAT CTCTATGAGA ATCCACAAGA GAATTTCACT TTGGTCTTGT TGGTAGGAAT TGTGCAGCCT CATCTGAGTA ACTAATGTGT TTTTATCTTA CAAACACAAG GAATATCACA TGGTTGTCCT TTGACTGGCT GTAAGGAAAC TCAGAGCTAG ATCTGAGACC CTCTCCTACC AAGTATATAA AACTTTGTGA CATACATTTT TGTGCCATAA CTTCAACCTT GGTTCCAAAT GATTTTTGTA CCCTAAGTTT AAATTTGGCT TTCTTTTTTT TTTTTTTGTA CTCAATAAAA CATCAAGCTC ATTTATTATT GCGAAGAGCG AAACAACAAA GCTTCCACAG CGTGGAAGGG GACCCGAGTG GGTTGCCCAA ATTGGCTTCT TTTTCTTACT TTTTAATTAA TTTTAATTTG CTATACTGAA CACATTTTGT ACTGTTCTCA CATTCTTTTT GAAAAAAGCA GAATATAAAT AAGTAGATAA CTTAAAAAAA ACTCTTTGAG CAGAAAGAAT CATTTGGGAG GCAATATATT TCAGTGGCTG TAAAGTGGCA TTCTAGAATC ATCCTACCCA GGTGAAAGCC

CTATTTTGCC ACCTGTAGTG TAGTGTGTAT TTGAACAGCT ACTTTCTTTT CTAAACTACA ATTTCTTCAT CTGTTAAAGA GGCATAATAA TTGTATCATC CTCATTGGGT TGATAAAATA AAATATTTCC AAGTATTTAG TTCAGGTCCT AGCACGTAGA CAGTGTTGCA TTACTGTTTT AATCCTTTAA AGTATTAAAG ACTACTATTT GAAATCTTTT CTTCTAAAAT TCAGCCTGCT GATGACCAAG TGCACTTGAG CAGGGGGAAT CAAATCTGAA TTAATTTCAG ATTCTGGTTA GCTTCACATA AATATTTTTT TTAGGGATGA TGAACCTAAC AGCAATAGAT GAGTAAGAAT CTGTTCCTAC TGAGAGAGTT TCATTTTGAA GAAAAAGGAA CTAAGGGGGC ATGTGTTCAG TTTCATGCCC TGGTCTAACC CTGTGTGTTG GTTCTGGTGG GAAATTCTTC CAACCGAGGA AAAAACCAGT TCACAAATCT GAAGACCAGT GATTTTAGAA GATGTATCTG GACTGGAGTC TAATCTCTGA

CTCTGGGTCC TGCTGATATG GTATTTTTGA GATTTGGCCT AAAACATCAT TGCCCTGGTT TCCTTATTTA CCAAACAGGG CCAATGGTAG TGACTAATCA GAAAATGATA ATGCCTGGTG CACAAAATGT GTCTAGATGA GCCCATGCAC AAGGACACAT GTTTCTGGAA CTGTTCCTTA TTCCTTTCCT AAAAGAAAGG AGGGAAAGTC TCCATACTAA GACTACTAGG GCAGGGGACA AAGTGCTAGA GTCAGAAGAT TCATCTGAGG ACAGAAGAAT AGGGGTGAAG GCTCTAGTCA CTTCATTGGC TACCATGCTC TAAATAGTTA CCTGTGCCCT TTTTCTAACT ATTAGAACCC AAAAAGCCTA TAAATTCTCT CTCTCTCTCT CTCTCTCTCT GTGTATATAT ATACATATAC ACACACACAT AGACACACAC AC CACCTAA ACACACACAT AGAGATTTAT GACTTTTTAC TTTTATCCTT GTAAATGCCA TTAACTATAT TTTGTCTTAG ATTTAGCCTG GGAATGTAGC CATTATTTCT

ACCATTGCCT CCATAGGAAA AATACTCTTC ATGTTTTAAA GGACCAACCT ACAACTAAAA TCTTTGGAAA GCAGAATCAT TTGTAAGTTG GTGAAAATGG AAGATGTTGT TTTATAAATG AAGACTTTTT _{ττττττττττ} TTTTGAGACA GGGCCTCACT CTGTTGTGGA GTGCAGTGGT GCTGTCATGG CTTACTGCAG CCTTGACCTC CTGGGTTCAA GTGATCCTCC CACCTCAGTC TCCTGGGTAG CTGGGACTAC ATGTGCATGC TACCATGCCT GACTAATTTT TTGTATTTTT GTAGAGATGT GGTTTCGCCA TGTTGCCCAG GCTGGTCTTG AACTCGTGGG CTCAAGTAAT CCTCCTGCCT CAGCCTCCAA AAGTGCTGGG ATTAGAGGTG ACAGCCAAGG TGCCTGGCCC ACAGATGAAG ACTATTTAAT GTTATCTTAA AGATACCCTA AGCTTCCTAC CAAGCCAGTG ATCTTTTGGG GCTTCTGTTT TCTTTGTTGG CATAACTGTA ACTAGCCTAA CTGCCCGTTA TCTGTTTCCT

GTTTGCCCCA CACTGATTCC CACAGCAGTT TTCAAGTTAT CGGTTTGAGA TCTTGTACAG AAATGACTCC AAGGTAAAAA ATTTAAAAAC AACCCCTCTA ATTTTTTTAC CCTTGCTTAT AAAACAGCCT TAGCCAGCTA ACCCCTCACT ACATGCAAAT GAGTTTGATT CTATTCTTTT GATTCTACAA ACACTTATTA AAAGATTTTA GAATTCGGAA ATAAATAGCT TCCTTATTAA GGTGACTTAC AGCCCCAAAG TCCTTAAAAT TATTTAGACA ATAGCCACCT TATCCCAGGG GGCAGTGTGT AATAACCCAC CCTGTTCTCT ATCCGTCAGT TCTGCCATCA TCGCCCAAGG TAGGAAGAAA GACAGGACAA CCGGGGTCAA GATTTGAAGT CTCAATGGAA AGAATAATCA GTGGTTGGAG AAAACTGTCA TTCTTCTTTT GCCTTAATGC AGTACTTGAT ACTTATACTT AGTACTGTAT AGTACTTAGT ACTGTATAAT ACTATAAGAT AGTGAGATTC AATCAGCACA GAATTTCTAA

TAGCAAGGGC AGAGACATTT TAACTGCTCA GTGCTCTCAG GTTATACATA GCTAATGAAG TTCTTGCATA TCAACAATCC CCACCCCCCT CACACACTTT GTCTTTCTGG ATTGGTTAGA AAACTTACCT AGCGCCCACT ATTCTCAAAT TTAAATGAAA GATAAGATCA GAGTGGCACG CAATTAGGGA CTGATAAATA ATATTTTTGT AATTGCCAGT GTAAATGGAC AGGGGGCAAC CTTTACATAC CATATTCAGT GAACAGAATA CGTACTAACT AATTTGATGG AAGGAAAATT AAAATGACAA TCAACTGAGC CCACAGAAAG GCAACACAGA GCAGTTGGTT AGCAATTGTT TCGAGATCAT CCCTGAACTT GAAACAGGTA TATCTTTTTT _TTTTTTχ_TTT TTGAGACAGA GTCTCACTCT GTCACCAGGC TGGAGTGCAA TGGTGCGGTC TCAGCTCACT GCAACCTCCG CCTCCCGGGT TCAAGTGATT CTTCTGTCTC AGCCTCCCGA GTAGCTGGGA TTACAGGTGC CCGCCACCAC

GCCTGGCTAA TTTTTGTATT TTTAGTAGAG ACAGGGTTTC ACCATGTTGG CCAGGCTGGT CTTGAACTGC TGAGCTCATG ATCCGCCCGC CTCGGCCTCC CAAAGTGCTG GGATTACAGG CATGAGCCAC CACACCTGGC CAAAACAGGT ATATCTTAAA AGCTGCCCAA TGTCCATGAA TGTTACAGCC TTGAATGGTT CTTCCAGGTG AGTTTGGCCA AATGTGGCAC CATACACCCA AGGCCTGCTG CAGGCTAGTG GGTTGCTCAC ACTTTAAAGC TGAGACACAC TCATGCCTTA AGGTAAAGGG AGTGATAATC TGGGCAGCAG ATGTTAACTT CTCAAGGCAG TCCTCCTTCT CTTTTCCTCT CCAGTGACGG ATGGTTGGAA AGCATATATG GTGCATTTGG TTAGAGCTGT GGCCTTGGTG AATAGATACT TGGGAGAATA CATGGGAATT TCTCCCAGGG TTAATGCAAT GCCCATGTGT TGGGAACCAG GTGACTCTTG AAGAGGTCAG GTATTTGGGA GCAGTGCCTT GAAACCTTAG

TGGACATTAG ACCCACTTCC TAGTGGAATT GTAGCATTGA AATCCAAGGC ATGTAGGCTC TTAGAGGACA GAGATAGTGT GTCATTTTTT CAGAATTAAT TAAGAGCAGG CCAGGCGTGG TGGCTCACAC CTGTAATCCA AGCCCTTTGG GAGGCCAAGG CAGGCAGATC ACGAGGTCAG GAGATCGAGA CCACTCTGGC TAACACAGTG AAACCCCGTG TCTACTAAAA ATACAAAAAA TTAGCTGGGC ATGGTGGCAC GCTCCTGTAG TCCCAGCTAC TTGGGAGGCT GAGGTGGGAG AATAGCTTGA ACCCAGAAGG CGGAGGTTGC AGTGAGCTGA AATTGCACCA CTGCACTCTA GCCTGGTGAC AGAGTGAGGC TCTGTCTCAA AAAAAAAAAA GTATTAAAGA ATTACATAAG AGCAAAGAAC CATTAGAATA TCTCACTTAG TTGTTATCAG CCTAGCAAGC TGCCTTGAAG GTAATAGACA TTTTTAAAAG TTTATCAGAT GAAAAGCGAA AATCAGCCAA CCTGTTTTAA TGAAGGTGTG

TCCTGGGCTG ATTTACATGT CTCCAGGGAC TGATGGCTCT AGAATGTAAA GCTTGGCATC CTGCTTGTGT TGAATCTATC ACATTTAATT TCCTGTGGGT TTCTTTTTTT TTTCTTTTTC ACTTTAAAGT TGTGTTCTTT TCATGTGAAG TTAAACTCAC ATACCTTTTT TTAATCTCCT TGCCAGCCAA ATGATAAATG CCAACCCAGA GAATGCAGTA ACCATGACTG CCACTGGAAT GAAGAGGGGG TTATAATCAC CCTCCTTAAT CATTGAGAAA CTTTTGTCCA ATTCTGAAAG AGAAATCAGT AAGGCACATA GCATGAGACC ACCAGCATTA TTTCCTTAGT CTATCTCATG ATATTTGACT TTTTTCCTCC TTACATCTCC CAGTAGTAGC CCATTTGATG CCATTTGACA GATGAGGAAA CTGGCATGGG AAGGCCCCTG ATGAGTCTAC AGCATAGGCA AAGACTGGAC CAGCCTTGCT AGTCTAATGC CTACAGAATC TCAATGCCCA GATTTGTGGT TCATAGAGTT CCTGAAAATG

CACCTAAAAA TGTTGGCAAG AATGGTCATC GTTGTATTTA GCTCCATGGA CTTGTTCAAT GACTGGAACT CTGAAACACA GAGAAGAGCT AAAAGCCTAA TACAACTTCA GGAAAAATAA AAGCCAATGA TCTGAACTGG ATAATTCACC AGTCAAAGGA AATCATTAAT GCTTTTACTT TAAAGCAGTT GTGCAAAAAT AAGCACTTGA TTTTTACATG CCAAGGACCT GCACTAATTT CTTTCCAATG CAGTAGTTAC CACTTCCCTC TACTTCCTTC ACGAATAAGT AAAAGGGCAT GTTTAGAGAT ACTCTTGTAA GTGTAAACTA AGTTCATTTG GGAGCCTCTA TTTGAAAATA CTGGTATAAA AAAAAATCTG TCTCCTGATA CTAACATTTG AAGGAATCTA CTTTTTTACA TATTGGCAGA GGGTCTGATT CTATCCTTAG TTCTTCCCAT TACTTTGATG AACCTTTTCA AGGTGATTTG ATCCCCACAC CCAAATATAT GATTGAGAGA AGGCTCAAGT TCCCAGGAGC TCCAGACAGA

AGGTACCTGT TGGCTTGATG AAGATGAGGA GGAAATGAAC ACTAGCTAGG CCTTAAAGGG AAATGTCTCT GATAGGCCTA ATACACAGTC CTCTGCTAAA GGCCTCCCTG CCTCTCTCTG CTCATCCACT CTACTCCCTG GCCCTGGGCA CGCAGCACAC AGAGATCAGC ATTTCTGACA GCTTCTGTAG ATCCTACCAT TTAAAGACTT TTGTCATCCA TGCAGATAGT CTCAGGAGCA GACACAGGTA GCTATTCTTT CACATGCTAG CTTAACATGC ATTTGCTTTA GCACCTATTG CCAGGCACTG TGTCAGGTGG AGGGTATACA AAGATGAACA AGACATGATT CTTCTCATAT ACAGATAGAT TTTGGAGGCA TTAGCTTAGT GATGATTCAG GAGTATCCAT TATTTGGGGA AGTAGGTGGT CATTAGTGAC CTTTTACAGG CATTTCAATG GGCTAACAGA GATGTTAGAT TGTAGTGGAA TAGAAGAATG GGTAAAAAGT AAATCAGTGA GTTCAGATTT TAGGAGTTAA GATGGCAAGA

GGTGAGAACA AAAAAAGGAA ATGATTGTCA TTAAAGGAGG AGGAAAGACC AGCCAAAGAT TTTACAGTGA GTTAAGCATA CAAATTTATT TCTAGGCCAC ATATTCTTAG CAAAACAACA TGTAAATGTT TATGTATGTC TTTCCTCATA TCTGCTCATC CATCAGCTCC ATCGTTAAGA TTTCAGTTTT CCAGGACAAA CTTACTCACT TTGACATATT GGACTAGGAT TTGACCAGAT TCCAGATGAT TCACAAATGG TTTTCTTCTT CCCAATTAAC TCAGTTCCTT CTGAGCAGAT GAAGGTACAT GCAGAGGTAA AGCTGAAGCT GGCCAGGGGA TGGCTACAGT TCATGATCCC CAAATCTGGT GCTGATAGAG GCTCACACTG AATCACTTCA ATGAAAAAGA AAAAAAAAAA AAAGACAAAA CAGTATTTCT GAGTAGAGAC CCTCCCTTGA GCAAAGGATT TTTAGCCAAA GCTGCCTGAC TACATTACTT GTGATATTGC TTCCAGGCTT TATTTTCTTG AGAATGATGG TGGGTGGTGA

ATGAGAGATG AAGGCAAGGA AGCATTGAAA GCTGTGGGGA GAGGAGTAGC TACTCCAGGC TGCTGCCCTA GCTAAGGTGA CCCTCCCCTT CTGCTGGAAG TACCATGCCA TATGGCCTCT GCATCAAGGG CTCTTATGGG ATATTCTCAG AGAATCTCTG CCGTTTCATC TGTTCTGATA TCTACCCAAG CATTTTGAAA AACATCCCAA TTCACTGAAG CAAGTCCAAC TTCCGTAAAT TCCAGTAGGT GGGTTGACAG TTTTATAATT TCAATAAGGG ATTTTGATAG CACTTCTAAG AATTAAACTA CTTAAACTAA TGCATCAGGA GCATACTTGT AGAAAAGTTA ACCAAAACTT CGTAAGTTCA GATGACATTG GTTTTCTCCC ATATGGAGAT AAGGTTGGCA GTTAAAAATG AAAAAAAAAA AAAAACCTAC CTTATTTCAA ACTTGAAAAG ATCAAGAGAT TGTGTTTTTG TTTTTCAGTT GTTATTCTCC TAAAAGTTTA TGCATGAGGA AAAGTAAAAG TGATTTTAAG AATAAGCCAA

ATAAAACAAC CAAGAAAGAC CTCCACTACC CTGGGAAGGA AACTGGTTGG TATTAAGTAG GACACCACAT AAAACAGGTG TTATTGAGAG GAGAAGAACC AAAATGTAAC TGAGGTTCAA CAAGACATTA TTTATGCAAT GGCAATGAGA AAAATAAAAA ACACAGTATA ACCATGCTGT ATTGCTATAA GTCATGTTAC ACACTGGGAG ATGGCTTCAG GGGTATTTGG TTTTTACTTT TTGTTTGGGA GGTTTTTCAA AAAAATTTAG TTAGAATAAG TCCTTTGAGA AACATCACAG TAGGTTAAAC AAAGTTAGGT TAAATTAGGC TCCTAAGTTT GACTTCTCAG CAAACTTCTA CTGAATGTTC TGACTGTAAG CCCAGGATTG CATGACAAAA CCTCTAGTCT GAAGTTACTC ACCTTGACAG GTTGGTTCTG GAGATGACCA GTTTCCAAAT GGTCCACAGG TGGTTTCTTC AATCCCAGTT AAGTTTGTTC CTTCAGAGCA GCTGAAGGCA CACTGTGAGC TGAAGGTGAA

GTTTCCCAAA GGGTGAGTAC AGTCCATGGT ACCCAGCTCT GGGGCCTCCA AAGGCTCACA CTGAATCACT TCAATAGGGA AAGAAACAGT ATGGGGAAGA GTTAAGAGGA ACTGACGCCT GGATTTGAAT CCTAGCCCTG CCACTTGATA ACCATGTGCC TTTAAACAAG GTTACTTGAA CCCTCCAACT TCAGTTTCTT CATCTATATA AGAGGAATAA TGAAATTGTG TTATCTTTAT CAAATTGATA TGGAAACTAA ATGTAATTCA ATTAGCATAA GTCAAGGACC TTAGAACAAA GCCTGACTCA TCAGAAATTC TAAGTAAACA TTAGCTAGTC TTCATATTAT TATCTTCAGC ATTATCTGTA GTGAGAATCC TTAAAGCCAA ATAGGTGTAA CTGGGAATGA CCAGCTTAGT CGGGAAATAA CTATCACATC AGAGCCCCTG AGTCTACTAG AGTATTGGGA GCAAGATGTT CAGAGAAAGA GTGGGTCTCC ATAATAAGCC TTCTTTGCAA GGAGAGAATA TAAAAGTCTA GGAAGCATTT

TGACCTCAAT TCTGTCTTCT ATTCTAGCTC AGTTCCAGAA TTTTAACTCT TTTGATTTTG ACAACCCTCT CCAGAAACTG TATCTATTTC CCTGTTCTGA TTGGTGGTAC AATAGGTAAA TTTAAGACTT GGAAATCAAA GTTTTCACAT TTTAGACCCT GCCATGCCAT TTAGTAAACA GTACAACTTT CATGTCTTAT TCCTCATCTG TCAAATTTAA GCCATTATTG CTACCTTGCT CTAGAGACTT CAAGGAAGAA TGGACTCAAG GAATCAGAAG AATTTTTGTA TTTGGAAACT ATATGAGATG AGATTAGGGA GAAACATGGG AACTAAGAGA AAATGTTATC TTTTTTCATT GATTTAAAGA GTATCTATTA TATATCAAGC ATTACTCTGG GGCTTGAAGA GCTTAGATTT CACCCTGTAG GACAAAATGG TAGGTAGAAA TTAATGGGTG GATTGTCATG TATGTGTGAT GTGTTTTAAT TGCTTTTAAT TGATCAGTCT CCCTGTAGTA TGAATAATGT ATTTGAGGGG AGCTAATTTA

AAATTGTGGA ACTCATCTAA TAAACTATTG CAAGAATCTA GAAGAAAGAT AATGACGGCA ATGGTAGTAG AGTTGACAAG TGGAAGACAA ATTAGAAAAA CACTAAGTTG TAAAAATTGG TAGAATGTTA CCCTGCATAA ATGTTGGGGG AGTTAAGAGA GTCTCATACC AGGGTGCCCA TGTAAATGGT GATTCCACAT ACTGAGATAA GAAATACGAA GAGAAAAGCT GACTGGGAAC AATTGGTTTT ATAGTCTTTT AAACATCCCA AAGGACATCC TTAGCATATT TGAGTTCAGA GCTGGAGATA GGCTTATCAG TCCAAAGATC ACATAGATTT GTGAGTCCGC AAAAGTCAGT AAGTTTGACC AAAGGATACA TGTAGATTAG AGTCAGAAGA GCAATATACA AAAGACAAAA GCTGAGAAAT TATAGTAGTT TATGGTCCTG GATAAGTGCT CATGAAGGAT CTCAGGAGAA ATGATCACAG GTAGAAAGAA TGAGAAAAGA GTGATATGAG AGAAACCAAG ACAAAGAAAA

GTAAAATGTT AAAAATGAGT GAAATAGGCA TACCAATAAT TAAAAATGAG TAAAATAGGC ATACCAATAA CATAAGGGTT AAAAAATAGA GTTCAAAAAT GGGGTGAGGG TAAAGTATTA GGAAGGAGTC ATGGCCCAGG GATCAAGTGA AATGAGTTAG ATCTATAGAT CTATTTCAGT TGGTTGACAT TTAAATGTAT TTTGGTTTTA ATTCTTTATT GTTTACAAAC ATTGCTTTTT TAAAAAATTA AATTGTCCAA TTCAATTCAG GCTCACAAGC AAGTGCCTCA TATATACAGG CATTTTGTGG ATCCCAAAGA TGCAATGATA AATAGGACAC TTACTGATCT CAAGAAGTTT TCAGTACCAG AGGAGACGGA CAAGTGAACA GATGACTTCA ACATAAGTGG GAGAAATGAG GAAGAAATAT GTGGAGCTAT CAGAACTAAG AAAGCTTCCT AGAAGAAACT GTCTTTGAAC AATGTCTTAA AGATGACATG TTTTTTGGCC ATGTGCAAAA TGAGAGAGAA

GGCCACCAGC AAAGTCAGTG TGCTACAGAG CACATGTGTT AAGTGTGGAG AACTGCAAGA AGGAAAGGAA CTACTAGAAG GAAAAAGCAA GATACTTTCT GGGTAACTCA GCCTCCTAAT GATAAATGGC ATAGTTTCTT CCAGACCTTA GAGTTCTAAT TAATCTAACA AGCTCATTAG ATCGTGAGCT TCTTGAGAGC GGGAATCTAC CATGCTAATT CCTTATGGTA ACCCTGACAG CTTTTATCCC AACACTGTGC TTCTTGTGGT ACTCAAAAAG ACTTGTTGAG AAGTGAGTCG AAACTTCATG CTGACTTATG AAATCTTTAC GGAAAGGTAA CAATATTGTG AAAGCAGAGC TTTCTGATCA AAACTTCCCA TTTCTCAGAG TGGCTAGTAT CATTTTGTTC CAACCAGCTT CATGATAAGC TATAATGATT CCTGTGACTT TACCTAAGAA GAAGCAAAGA AAGGAAAGAG ACTTACCAAA CTGACACTGG GGCCCATAGT ACCCCACATC ACAGTTGCAG GTGTAATTAT

TGATGATTTC TACACATTCT CCATGGCCAC TGCATGACCA GGGCTGGCAA GAAGCTTTAA GGAGGTCAGA AAAAAAATAT TTTAATGTGA TTACATTTTA GTACTCAAAG TCATTTCTTT AGACATAGAT AACCTTTTGT CTGAGATGAT TTAAATAATC AGGAAAGGTT TATTTGTAAA TTCATAGCAT AAAAATCATA TGCTAAAATT TTTACGTATA AAATACACTA AGCATATAGT CATAGGCATT TATTTGCTTT TGGAATGAAA TTACCAATAC TAATATTCTG TAACACTTAT AGGAAACTTA GTGGCATACC TTGAAACTCT TGAAATTACT TGTTTTTAAT GAGTGAGAAG GTTAAATGAT GACCTGACCT CAATCATTTC TGCATGCAAT TATTTCTTGG CAATCCCTTT CTTTATAGAA ATCAAAGATT AAAAAGTCCA AATTTGCTAA AACGGTAGAG TCCAATTTAT AAGAGACCAA ATTAACTATG GTTCATTATT AAAACATCAC TTGGAAAATG CTGGCTGTTT TGGAATTGTA GAAGATTTTA CAGAAATATT CATACACCAA AGATAGTGCA ATTTTTATAT AAAATTATAT AAGGTTAGAC CAAGAAGGAA GCACGCAGCA CCACACTCTC TACTTCACAA TGTGAAAACT GAGGTGATGT GAGCCTAAGT TTCCAACTGG CCCCAGCTGT CAGCTTCTCC TCCCCTGCCT TATTATCAAA GGCACTGATT GTCTAGCTCT TCCTCTGTAC TTCCTACGTA GATCTATCAT TTTGATGTAA CTTGATTTAG GGGTATAGCT TTTGTGCACA GGGACAAATC TTACACACCA AAAATTCTTA GGAGTGACAC GATGCAAGAT TATATAGAGG GCTAGATGTA TTTTAGAATG AACCAGAAGC TGTTCTCATC CCCCCAGCTT TCCATGGGGT AAATCTGAGT ATTCTCTTAA CCGTGGCCCT TCCTGAGTCT

GAGGCAGCAT AGCCGTCTTG TCACTCCCTA CCTGTGTAAC AGAGGGCTGC CTTTAGTTTG TGGCAGGCGT CATCGTTCCA TTTGCCTGCA TCTTTGTTTC TCTTGATATA GATCTCCACG CAGTCCTCCT TGTTCTTCTT GTTGTTGGGC TCACCATCTC CCCAGTTCTC TGCTTCTTCA GTAAGAGATT TGTTGGTTCC CACCCACGTC CATATTCCTC CTATCTTCCG GATTCCTATC CAGTAGTAAG AACGACTGAA AGGCAGAGTC TTCTCCAGAT ACTCAATTTC CGCCTTGTTT TGTATGGCAA CTAAATCTGT GTAATTGTCT CGGCAGAATC TTCTAGCCCT TTGCCAGTTC ATGGGTTTTT CAGAATAATG GTAAGTCCAG CAGTCGGTTC CATGATGTGC CAGGAAATCT GCAAGACATC AGTGTGACCT ATGCAGACTT ACATAATGTT ACAGCTAAAA AGAACCTAGC ACTACTCCAG GCTGAGCTAG ACACTTAGAG ATGAGGAAAC AGAGCCTAAG AGTGTATGTG ACCATCTCAG

GATCACAGAA TAGTTGTTTG CAGATTTGAA GTAGAACCTA GACCTTCTGG CTTGAATATA AGATGCTTTT ATCTAAGGTT CTATTTGAAA CAAATTTAGT GGTTTTCTAG GTTTATTTTC TTATTAATTT TTTTCTCAAA ATTATTTCAG GTGAAATTTA ACCAACATAT TTTAGACATT CATATTTCTT TTTCTTTGTA GCTGTTAATG ATTTACAACT AATTACCGTG TAATATCATA TAACTATACA ATTTACGTAT ACTTTTTAAT CCTGGAATCA TTTCTTGAAG GCCAACACAT ATGTACCTAT GGGAGAAGCA TAATAAGGAC AGGAAGAACA GTGACATACT TTTAAGTAAC CTCTTTTACA TAAAAAACAT TTTATTTTAC CATAGGAAGA ACTGCTTCTG GAAAAGCCCA ATATACCACT CAACTCTTAT ATATCTAACT GTATAATTTT TAAAAAGAAC AATTTACAAA GCCAAATGGT ATAGGATTAT GAAATTCATT AGATCATGTT CTATACACAA AGAGACTCAA CTGATGATGT

TTAATAAACA TATGGACCCA TCAAATATGA GGGCTTTGAA GATATCTAAT TAAACACATA ATTACACAAT GACTTCATAA TAATATATGG CATTCTAAGC ATGGTATGAT CTACATGAAT CACTATTTAA TACAGTAAAG AAACAGATAT AATTGATGGT AAAGAGCATC ATAAAATAAA CATTTTGAAC AGAGTTTTGA ATGAGCATTC CACTAGAATG CAAGTTCTAA GAGGGAAAAA ACTGTTGTGT CCACTGCTGT ATCCTTAGTG CCTAGCATAA ATTTCACACA TTGTAGGGAC TCAGAAAATA CCTGTTGTAT GAAAAGAGCA CTAAGTTTCT ATGTGACACA GTGCAGACAT GGCATAAGGA ATGTGTGAAC GGGAGAGTTA GCATGTTTGC TTGGCTAGAG CTGAAAATCC AGGCTAGGGA GAAAGAAGAC ATTAGTTTAC TTAGGAAATG AAAAACCAAG TTCAAAGCTA TTGCTGGAGA GTCTTCAAGA ATCAGATATA AAATTTGTCA CAACAATGGG AGAAGGACCA AAAAATGATA

AACCCCCGTC CCTTAATAAG CTCGTATTGT AATTGTAGAA ATGACATTAA TGTACACTGA ACTATGAATA AAAAATAGAA AATGAGGTGC TAAATATTTG GTACAGATTG TAAGTACCTT AACAGAGATT TCTTAATTAA CATTATTCCT TTATAATTGA GGGATTTTGT GGGGTTATTG GGATTTGAAC TCTACAGCAT GGGCTATTAT AGGTTAAAAA TAGTGTTCAG GAGTTTCTGG GGAAGAACTA AAGGTAAGAA GAAAAGAGAT GTTTACAGAA GGGATAGAAT TAACAGCTCT GTGAAATAAT TTTCCCTTAG ACTATGTATA ACTAGTGGAT ATTTAAGAAA AATGAATATA AGTAAAATAG ACTTAGCGAT ATATAAATAT CATAACATAC CACAACAGAG CATTGTCCAC CCCCACAACT TGAAGATGTT CCATAAGTCC CTCTGGGTGC TCTGACATTT CCATGGAAAT ATCTGCAAAT GAAATACAAA ATTATATTTA GATGTATACT CTTAAACCAC ACATTTATAG CCTTTGAGGT

GGTGCTTACA ACTTTCTTAA TAATCAGAAT AAAACACATA TGTCTACTAA CCCTGTCTGA GGTAACAGGT TTCTCAGACA TAGATGAAAA ATTACTTCAA ATTTACATCA GAACTGATGC ACAGTTTTGT TTTGTTCTAT TTTATTTTTA CGCTTTAGTC TCAAGTTGCT AATCGGTACT GCCCTGAATT TTTTCTATGG TTTGGTAATT TTTATACCTG CTTTTCTGCT GAGCTATTAG ATAAAACTAT TTAATATTTA CTATGTATAT TTTTTAAAGT ATTGTTGCTG CTTAATTAAC TATTGATGCT TATATTTAAT GTTATAGCCT CACTCTTGAT CATAATGGGT CAATGCCTCA AATACCTAAA AAAAAAAAAA ATTAGATAGC CAGACACCAG GAAAGAAAAG TATTTCTTTT TTTAATAAAA AGAAATACCT TTTTGAGCAA CTGAAATGAC AAAGTCACAA ATTTCCTGCA CACCTTAAAA TATACTTAAT GTAAATGACG AGTTAATGGG TGCAGCACAC CAACATGGCA CATGTATACA

TGTGTGACAA ACCTGTATGT TGTGCACATG TACCCTAGAA CTTAAAGTAT AATTTTAAAA AAATTCTATC TTCCAAAGCA TATCACTTCT CAGGTAGACA CAGTGTTTAT TGCAAAAGAT CTGATTTCAA TAGTATTTCT TCAAGAGTCT CCCCAGAGAC AAAGTCAAGA AGAGGAAATC AGCATATCTG AGAAGAAAGA TTTCAGGATC ACTTTTTTTG AGGGTCTGAG AAAATGTTTA GTTTCTATAT TATTTAAAAC CAGAATTGAA ATGGGGTGAT TCCTATCCTT GCCACCTGCC TCTACAACCC CAAGAGTTTC TATCTGAGCA TCTAAACGTC TTTTAGGCTG AAAGGCTCAC CATGGCTTTG CTTGGTCCTT CTCTAGTTCT TCTGCAGCCC ATTGAGCCTC TTGACTTAGC ACAAGGGTCT CAGGTCCTTG CCCAAAGGGA GTGTGCTGTG CTGCAGGTAG ACTGCACTGA ATGTCAACAG AAAGCCTTGC TTTCTTTCAT TTCTCTAACC CAGTCTCACA TCCTCCTCCT CCTCCCCTTT

TCCCTCCCCT TCCTCCTGCA CTTCTCTTTC CTCTTTCCCC ACCCCTTTCC TAGACTGGCC TCTATTGCCT CCCACTGAGA CAAAAATGAA CTGCTGATCA GAAAGTAATG TGACTAGATT CTCTCTTCCT TCCCTCCTTT CTATCCTTCC TTCCATTCTC CTATGCATCT TTCCTTACCC TCCTCCTCCT TCACTCATTG TTGTTGCTGT TCTTCTTCCT CTTCTTTTTC CTCCTGCTCC TCTTCTTCTA CTTGTTCTTG TTCTTGTTTT TGTTTGGTTC TTGTTCTCCT CTTCCTCCTT CTCTCTCTCC TCCTCCTCCT TCTTTTCCAC CACCCTCCCC TATCTTTTTC ATAAATGCTA AACTAACTCT TGGCTACCTG TGGTAAATGG CCCTTGGAAA TTGCAAATAC TACAAATCAA AACTGCATTT CAGACATATT TATGATGTTT GCAAAACTTC AGTAGAGCTA AGCAGTGGAC TTGACTCGTT TCGGTTCCTT CACCTCCGTC TTTCCTTGCT CACCACCTAG TGGACGTCCT TGTTAGTGGC

ACTTCCTGAA GTTAACCCCT GAAGAGAGCC CATGCTCTCT AGCTTTTCAC CGTGTAGGTT TGGGAGCCTA CAAGTACCTT TAATATTCTT GGACTATAAA ATGAGATGGT TTTATAAGAC TGCATGTGAA ATTAGGACCC ATATGATGAA GGACAATAAA AAGGAAGACC CACTGATGTG AGTCAATGAG TCAAATGCAA ATCAGATTTG CATTTTTAGG AAAATAATAA TAACAACAAC AAAAACTCTG AAGCTCAGCG CCCCATATTT ATTATATTGT TTAATCTTTA TAACAGCTCT CTGCTATAGA TATGATTATT ATCCCCATTC TAAAGAGTCT CAAAGAGGTT AAGAAACAAA TTCAAAAACT AGCGAAAGAC AAGAAATAAC TAAGATCAGA GCAGAACCAT AGGAGGTAGA GACACGAAAA AGCCTTCAAA AAATCAATAA ATCCAGGAGC TGCATTTTGA AAAGATTAAC AAAATAGATG GACCACTAGC TAGACTAATA AGAAAGAAGA ATCAATAGAC ACAATAAAAA

ATGGTAAAGG GGATATTACC ACTGATCCCG TAGAAATACA AACTACCATC AGAGATTACT ATAAACATCT TTACACAAAT AAACTAGAAA ATCTAGAAGA AATGGATAAA TTCCTGGACA CATACACCCT CCCAAGACTA AACCAGGAAG AAGTCAAATC CCTGAATAGA CTAATAACAA GTTCTGAAAT TAAGGCAGCA ATTAATAGCC TACCAACTAA AAAAAGCCCA GGACCAGATG GATTCACAGC CAAATTCTAC CAGAGGTACA AAGAGGTGCT GGTACCATTC CTTCTGAAAC TATTCCAGAG AATAGAAAAA GAGGAACTCC TCCCTCACTC ATTTTATGAG GCCAGCATCA TCCTGATACT AAAACCTGGC AGAGACACAA CAAAAAAAGA AAATTTCAGG CCAATATCCC TGATGAACAT CATTGCGAAA ATACTCAATA AAATACGGCA AACTGAATCC AGCAGCACAT CAAAAAGCTT ATCAACCACA ATCAAGTTGG CTTCATCCCT GGAATGCAAG GCTGGTTCAA CATACACAAA

TCAATAAACA GAATCCATTA CGTAAACAGA ACCAATCACA AAAACCACGT GATTATCTCA ATAGATGCAG AAAAGGCCTT GGATAAAATT CAACACCCCT TCATGCTAAA AACTCTCAAT AAACTAGGTA TTGATGGAAC GTATCTCAAA ATAATAAGAG CTATTTATGA CAAACCCACA GCCAATAGCA TACTGAATGG GCAAAAACTG AAAGCGTTCC CTTTAAAAAC TGGCACAAGA CAAGTATGCC TCTCTCACCA CTCCTGTTCA ACATAGTATT GGAAGTTCTG GCCAGGGCAA TCAGGCAAGA GAAAGAAATA AAGTGTATTC AAATAGAAGA GAGGAAGTCA AATTGTGTCT GTTTGCAGAT GACATGATTG TATATTTAGA AAATCCCATT GTCTCAGCCC AAAATCTCCT TAAACTGATC AGCAACTTCA GCAAAGTCTC AGGTTACAAA ATCAATGTGA AAAAATCACA AGAATTCCTA TACAGCAATA ATAGACAAAC AGAGAGCCAA ATCATGAGTG AACTCCCATT CACGATTGCT

ACAAAGAGAA TAAAATACCT AGGAATCCAA CTTACAAGGA ATGTGAAGGA CCTATTCAAG GAGAACTACA AACCACTGCT CAAGGAAATA AGAGAGGACA CAAATGAATG GAAAAACATT CCATGCTCAT GGGTAGGAAG AATCAATATC ATGAAAATGA CCATACTGCC CAAGGTAATT TATAGATTCA GTGCTATCCC CATCAAGCTA CTACTGACTT TTTTCACAGA ATTAGAAAAA AACTACTTTA AATTTCATAT GGAACCAAAA AAGAGCTTGT ATAGCCAAGA CAATCCTAAG CAAAAAGAAC AAAGCTGGAG GCATCATGCT ACCTGACTTC AAACTATACT ACAAGGCTAT AGTAACCAAA ACAGCATGGT GCTGGTACAA AAACAGATAT ATGGACCAAC GGAACAGAAC AGAGGCATCA GAAATAACAC CACACATCTA CAACCATCTG ATCTTTGACA AAGCTGACAA AAAGAAGCAA TTGGGAAAGG ATTCCCCATT TAATAAATGA TGTTGGGAAA ACTGGCTAGC

CATATGCAGA AAACTGAAAC TGGATCCCTT CCTTACACCT TATATAAAAA TTAACTCAAG ATGGATTAAA GACTTAAATG GAAGACCTAA AACCATAAAA ATTCTAGGAG AAAACCTAGG CAATACCATT CAGGACGTAG GTATGGGCAA AGACTTCATG ACTAAAACAC CAAAAGCAAC AGCAACAAAA GCCAAAATTG ACAAATGGGA TCTAATTAAA CTAAAGAGCT TCTGCACAGT AGAAAAAAAA AAACTATCAT CAAAGTGAAC AGGAAACCTA CAGAATGGGA GAAAATTTTT GCAATCTATT CACCTGACAA AGGGCTAATA TCCAAAATCT ACAAGAAACT TAAACAAATT TACAAGAAAA AACAAACAAC ACCATCAAAA AGTGAGTGAA GGATATGAAC AGATGCTTCT CAAAAGAAGA AGTTTATGCA GTCAACAAAC ATATGAAAAA AAGCTCATCA TCACTGGTCA TTAGAGAAAT GCAAATCAAA ACCACAATGA GATGCCATCT CATGCCAGTT

AGAATGGCGA TTATTAAAAA GTCAGGAAAC AACAGATGCT GGAGAGGATG TGGAGAAATA AGAATGCTTT TTACAGTGTT GGTGGAAGTG TAAATTAGTT CAATCATTGT GGAAGACAAT GTGGCGATTT CTCAAGGATC TATAACTAGA AAAACCATTT GACCCAGCAA TCCCATTACT GGGTATATAC CCAAAGGATT ATAAATCATT CTACGATAAA GACACATGCA CACTTATGTT TATTGAGGCA CTATTCACAA CAGCAAAGAG TTGGAACCAA CCCAAATGCC CACCAATGAT AAACTGGATA AAGATGATGT GGCACATATA CATCATGGAA TACTATACAG CCATAAAAAA GGATGAGTTC ATGTCCTTTG CAGGGACATG GATGAAGCTG GAAACCGTCA TTCTCAGCAA ACTAACACTG GAACAGAAAA CCAAACATTA CCCATTCTCA CTCATAAGTG GGAGTTGAAC AATGAGAACA CATGGACACA GGGAGGGGAA CATCACACAC TGGGGCATGT CAGGGGATGT

GGGGCTAGGG GAGGAACAGC ATTAGGAGAA ATACCTAATG TAGATGACAG GTTGATGAAT GCAGCAAACC ACCATGGCAC ATGTATACCT ATGTAACAAA CCTGCACGTT CTGCTCATGT ATCCCAGAAA TTAAAGTATA ATTTAAAAAA AGTTTAAAAA AAGAAAGTTG CCTTAGTCAC ATAACTAGTA AGAGACATGG TTGGGAATTT GAACAGAGGC CAATCAGTTC CAAATCCATG CTCTTGATCA TTAAGCTGAA CTTATGGCAG GAACTTGGAA GACATGGTAA AATGGGGAAA AACGTGGAGC CAGGGAGACT TGTGAAAGTG CCAGTGCTCC CACTATACCC TGAAAGAAGT ATCTAGACTT ACTTTTTTCT AAGTCCTCTC CTCTAATTCT CTCAATCTCT CTCTCTCTTT CTCTAAGAGA TGGGAATGGT GCTCTGTCAC TCAGGCTAGA GTGCAGTGGT GCGATCATAG CTCATTGCAC TCAAGGAATC CTAGGGTCTA GTGCCCCTTC TCCCTCAGCC TCCCATGTAG CTAAGACTAC

AGGCACATGC CCCAACCCTC GACTAATTTT TTTATTTTTT ATTTTTGTAG AGACAGGATC TCACTATGTT GCTCAGGCTG TAATTCTGTC TTGAAGCTTG TCCAATCAGG CTTTCAGCCA CACCAATTCC CTGAGACTGC TCTCACCAAG GTCCTACACT TCACTAACAC AAACAGCCTA TTCTCCATCC TCATCTTACT TCACCAGGGA GCTCCTGGTT TTCCTCCTAC TTCACTGGCT ATTTCTTCTG TATCATGTGT TGATTCTCCC TCATCTCCCC AACCTCCAAA CCCTTGGAGT ACTCCAGAGA TCACCGCTTT GCTCTTCTGT GTCTAACCTC ACTAACTTGG TGGTCCAATT CACACTCTTG ACTTTGAATA CCATTTAAAT GCGAACGAAT TCTAAATTCT GTACAACCAG AACCATTCTC CTGTAGCCAA ATGCCTACTC AACATCTCCA TCCCCAAACA AATTTAGTTG TTCAATAAGC CTCTCATATT TTACATATCC CAAACTGAAC TTCTGAATTT CTCCTCCAAT CTGTAGGGCT

CTTCCCACAG CCTTTCCATC TCAGTGGATT ATAACTCCAT CCTTCCAGTT ACTCAGACCA AAACTTTTGG AGTTAACTGA GACACCTCTC TTTTTTTTCA CAAGTCATAT CCAATGTGTC AACAAATTTT GGTAGTGGAA ATATTGCGGG ATTTTTTAAG AAATCAGAGA GACCGATGGG GTTCAGGAGG ATATTTATTA TTTAGGTGCA CTGGCCAAGT CAGATTAACA TCCAAAGGAC TGAGCCCTGA ACAAAGAGTT AAGTTACCTT TTAAGCATTT TGTGGGGTGG GAGAGAGGGG TATCTGTGCA GGGGGAAGCA TACTACAGAA GTGAGAAATA AAGACAGTTA TTCAATTAAT TGAGACATGC ATTACATCAT TTCTTACTTT TCAAGAAGAA ACATGTTTTG CGACTTGAGT TTATCTGTCT AGTGACCTTG CAGCTGCACA GCTAGAGAAA CAGGGTCTTC ACAATGCCTG GGAAAGGAGG AGAGGTAAGT CTCACTAGCC ACAGAAAAAC AGGCAGTTAA TTTTTAAAGG GCTCCAGCTC

TTTCTCTTTC TCAGGGGGAG TTGGGTTTTG TTACATACAA CTGAGTTTCC GCTTACACAT TATTTAATTT CTTTTAATTC CTGTTCCAAA AGAAGCCAGA TACAAAAGGT TACATGTTGT CTGATTCCAT TTATATGAAA CATATAGAAG AGGTAAATCC ATAGAGACAG AAAGTAGATT AGAGGTTCCC AGGGGCTGAG GAAGAAATGG GGACTAACTG CTTATAGGGT ACAGAGTTTT CTTCTGATAA AAATATTTTG GAACTAGATA GACATTTTGT TAGGCCATTC TTGCATTGTT ATAAAGAATT ACCTGAGACT TGGTAATTTA TAAAGAAAAG ATGTTTAATT GGCTTACACT TCTGCAAGCT TTACAGGAAG CATGGTGCCG ATATCTGCTC AGCTTCTGGT AAGGCCTCAG GAAGCTTACA ATCATGGCAG AAGGTGAAAG GGGAGCAGGC ATATCACATA GCAAAAGCAG GAGCAAGAGA GGGATGTGGG GAGGTGACAG TCACTTTTAA ACAGCCAGAT CTTGTGAGAA

CTCATTCACT ATCATGAAGA CAGTACCAAG AGGATGGTAC TAAATCATTC ATGAGAAACC CCACCCTCAT GATCAAATCA CCTCCCACCA GGCCCCACCT CCAACACTGG GGATTACAAT TTGACATGAG ATTTGAGTGA GAACACGGAT CCAAACCATA TCAGAGATGG TGGTTATACA ATGCGATAAA CGTCACTGGA TTGTACACTT TAAGATGGTT GTTTTATGTT GTGTGAACTT CACCTCAATA AAAAAAAATA TTTAATGTAC ATTCAGCCAA AAGAAGATTT GGAATAGGAA AGGTCATGGA GATATATTAA CAGCCATTTG ATGGGTGGTA AGGAAAAGAG TGGTTATTAG ACTGTTTTGT GGCCCTCAAA AGGTAGAACT AGATCGAGTT GGTGAGCATT ATAAAACCAT CACAAAACCC TGGAGAGAGG ACCCAGTGCT GAAGAACCGT TTGCCTGCCA TGAGACATGA GGGAAGTACC AGTGAATGCC ATTGAAAGCA GCATCCCTGG GTCCAAGGGA TGGTCAAAGG ACCACTACCC

AACCCTTCCC TAGCCTACGC CTCCATTACA GATGACCGCA AGATTTATTT GCTCATTGCT GCCAACCAAG GCTGCACTCA CTGCAGTTGC TATCAGTTTA TCATGGGTAA AAGGAATGTG CAGTAGAGAA CTAACTAACT GCCCACCTAC CTCCACAATC CTATCAGGAC AAATCACCAT GGCTCACATT TCCTTACATT TGGCATGTAA GCCCCTCTTA CTGTCTGTCA TCTATCTCCT ACACAGTTCA CCTAAACTGT TCTCTCCTGA CCCAACCTTG ATTTTCATCG CAAATGCTTC CTTGCCATCT CTGGGATTCC TGTCTTCACC ATCACCAAAC TCCCCTCAAT CTTCCAGTTT CCTGTTCAAA CTTTTCTCCT ACCTCCTTGC TTTGTCATTA GCCCGACTGC CTCCCTAGGA CATCACTTCC CCTGCAGATC TCTCAAGATG ACAATATTTA TTCTCCACAC AGCACATACT TCAGGGTTGG AAGGCAGGGG CAATCTTCTC CTTTATAATG AGTGCCTCTT ATATATGTTT ATTCATCTGC CCTCTTGTAA AACACACACA CACACACACA CAAAGAAGAA ATAAAATAAC TCTGCTTCTT TGAAGCTTGT GACACTGAGA TAAACCATCT CACTGTCCTC ATTGTAGTGA CCTCTCAACT CCTCATGCAA GATTGGCTTT GGCACCTAGT TCCTGATCTT CCTTTCCCTG TAAGCACTTC TCATAGTCTT ACGGGACTTC ACCATCCATG GCACAACCAA TACCACAGCC CAGATCCTCA GCTCTCCAAT GACATTTTCC TCCACTAGAC TTGAGCTACC TCCTTCCCTA GGCACAGCCT CAACCTCGAC AACACCTAAG ACTGTACCGT CTCTAAAGTC ACATGTTCAA ACACTTCACT CTTTAACCAC TGTCTCCTAT TCTTGCAAGT GTATTGCTCA AGTATCTCAT TGCAATGCTT TTTACTTCTA CCTCATTGAA

CCTCCAGGCC ATTAAACATT TCCTTATTTC TAACCATCAG GTTTCTCCTT ACTTGTTTGT TTGTTTATTT GTTTCTTTTT TTTTTTTTTT TTTGAGACAG GGTCTCACTC TGTTGCCCAG GCTGGAGTGC AGTGGTATGA TCTCGGCTCA CTGCAGCCTC CATCTCCCTG GTTCAAGTGA TTCTCATGTC TCAGCCTCCC GAGTAGCTGG GACTACAGGT GCATGCCACT ACGCCTGGCT AAGATTTTGT ATTTTTATTA GAGAAGGGGT TTTGCCATGT TGGCCAAGCT GGTCTCGAAC TCCTAACCTC AGGTGATCCA CCTGCCTCAG CCTCCCAAAG TGCTGAGATT ATAGGCATGA GCCACTATGC CCCACCTGGT TTCTCCTTAT TTATTTCAAG TCTATGCTGC ACTATTAAAA CTGCCTTGAC AAAAATTATA ATAGTGAGAA AATTATGACA GTGAAAGAGA TCTGAAATAA TCAACCCCCA TCTTGCCTTT ACCTTCCAGA CTGCCCTTAA TAATTCCTGA GCTTGGGCCA AGCTATCTTT

GGCAGAAATT TAGTTTATAG TTTAAATGAT AATAGCCCTT CTCCAAAACT AAACTGCCTT TGTAAAACTA ATAAAAGACC ACCAATGAAA GGTTAGGAGG ATGAGAGGAG CCTGAATTCT GCTAAGGTGT AGATGTAAAC AATTACCAAC TGTTATTCCG GAGGTCACAA GATTTGCAAC ATCGCCAATT ACTCCTGCAG ATAACAGCAC TATCATAGAA TCTGATTGGC CTTTTGAGAT GTCTTTTCAG ATTCTTACAT TTCAACTGGT GGCTCTACCT GGACCCATCA ACAAGTCCTG TGGCTCCACC CAGAAGCAGA CTTAACATGC ACAAGGACCA TTTTCCACAC CGCTATGATT GCATCCCAAC CAATCAGCAG CAACCATTCC TCTGCCTGCC AAATTATCCT TGAAAAATCT TAGCCTTAGA ATTTTGGGGG AGGCTGATTT CAGTAATAAC AAAACCCCGG TCTCCCATTT GGCTGGCTCT GCATGAATTA AATTCTTTCT CTATTGCAGT TCCCATCTTG ATAAATCACC TTTATCTGGG

CAGCAAACAA AAGGAACCCA TTGGACAGTT ACACTGTTGG CAGATATATC TTGCTTCCAA AATTGGATTT TTGTTTAATG AATTTATTCT GTTTTCTTGA TATTTACAAC TGTGAATGTT GTGTCTGAAT TCTCTTTATT TCTTGTTGAA AAGAACTATA TTGCTACAGC CAGTACATAC AGATGGATAG CTAATTACTC AACACGGGGG GATGTGACCA TCACCGCACT GTGCAAATGA ATGTTACCCA TTGTCCACTT TTCCCAAACT ACATAGTGTT ATATGGTATA TGACCCAATC AACGGTGGCA AAGCTCCAGA AATACCACAT AGACATCAGG GACACTTTAA ACTAATCAGC CTATAGTCCT TTTTCAGTAA TTTCCAAACC TGGTTGTGCA TCCAAATCAC TTGGTAACAT TAAAAAAACA AAAAAATATA CACGCAACAT TCGCTCCCAA TCCTACTGAA TCAGAATATT TTGGGTTGGT TCAGGAACAT TCAGGAGTTT TTCAGGGTCC AAGGTTTATA TAATTTGAGG TCTCTCTTTG

AGAAAAGGAA CGTAAAAGCG TCTTGCTTTT ATAGATCTTA CAAAGATGTA TTACCATGTA AACACATTCC TAGGACCCAG GCCCTTGTAA TTTAAAGGTT TATCTAAGTA ATGGGCCCTG AAGCTTAATT TTCATTATCT TCAGGGCAAA TTACCTGTGG GTTAGGGTTT AGGAATATAT CTCTCTGTGT ATGTGTGTGC ACATTAGCAT GTACGCTTGT

GTGGATTTTT _TTTTTTTTTχ TTTTTTTTTC TGAGACAGAG TCTCGCTCTG TCGCCAGGCT GGAGTGCAGT GGCGTGATCT CTGCTCACTG CAAACTCCGC CTCCCAGGCT

CAAGCGATTC TTCTGCCTCA GCCTCTTGAG TAGCTGGGAC TATAGGCACG CACCACTATG CCCAGCTAAT TTTTGTATTT TTAGTAGAGT TGGGGTTTCG CCATGTTGGC CAGGATGGTC TTGATCTCTT GACCTCGTGA TCCACCCGCC TCCACCTCCC AAAGTGCTGG GATTACAGGC GTGAGTCACC ATGCCCAGCA CTTGTGTGGA TGTTTTAAGC

TCCCAGGTGA GTGAATACAA AACTAGATCT TTCCCTTCTG TAGCATCTGT ACTGTTTACT CTATGCATCT CAATATTTTT TCTTTTAGTA TCTTTCCTTT TTCTCTCTTA TTACTTCCTC TTGTGCTATT TTTACACCTC CTTTTTTAAA AAATTTTTTC CCTTTTATTT CTATTGACCT TTAGCCCTCA CAATGATTCC TACAAGCCCC ATTTCTGTAA ATGGGGATTG AAATAATTGC TGGACTTTTG AGAGATAGAT ATATTAAATT GCAAACTGGC AGTAGTGGGG GCAGTTGATA CATAACTAGG TTTTAAAGTC TAGCCTTCTG AGACCACTCA TTCCATTTGT GAAAAGTGAT TCTACTTCTT ATTATGAGCC AAAATATGCA TTCATTCACC CATGCATTGA TTTATTCATT CAATAAATAT TTGTTGGATG TCCACTCTGT ATCAGGAATG TGCTAGGTTC TGGGAATACA GCAATGAACA AGGTAATTTT TCCCTACCCC TAAGGAACTT AGAGTTTAGT GGGGAAGACA GACATTAAAC

AAACAATTGT GCAAGTAATA ATCTATAATT ATTTATTACA ATTAAAGGAA GGAAGAGACA TATGGATTAT GAGGGCATTA AAGAGGAGAC CTAGTGTAAG TAGCCAGTTC TCGTGAAGGG ACATGTATTA GTTGGAGTTC TCCAGAGAAA CAGAACCAAT GGTGTGTGTG TGTGTGTGTG CGTGTGTGCG TGTGTGTGTT GGGGTGTGGG GGTGTGGTAT TTTTTATAGA AATTGTCTCA CACAATTATG GAAGCTGAGA AGTCCCATGG CCTGCTGTCT ACGAGCTGAG AACCAGGAAA GCCAGTGGAA TACTTCAAAG TCCAAAGGCC CTGGAACCAA GAGTGCCAGT GTTGGAAGGC AGGAGAAGAT GGGTGTCCCA GCTTAAAAAG ACAGTGAATT CACTCTTTTT GCTCTACATA GGGCCTCAAT GGGTTGGATC ATGGCCACCC ACATTGGTGA AGGCAATCCT CTTAGTCTAC CAATTAAATA CTAATCTCTT TGGAAATACT CTCACAGACA CACTGAGAAA TAATGTTTTA TCAGGGTGAT

AGAAATCTTC TGGAGTTAAA CAATGGTGAT AGCTGTACAA TCACATACAT TTTTAAAGGG TGCGTTTTAT GGAAAGTGAG TTTTATCTAA ATAAAATTTC TAAGAAAGAG ACTTAACACA GAGATAAACA TAAGCACATT TATTGTCAAC CTTTATAGTG TTATGTCAAA TAGGTCTGAC ATAAGCTTAA ATAAATATAT ACTTTAAAAA TTATAAAATA TTTTAAGTTA TAATTTAAAA TTCTCAATAA AACTCAAACA CAAACCACAC TGGTATTTCA CACAGCTAAT TTCTAATGCA GTTTACATAA ATATTTACAA CACTTAAACA ATTTCAAAGA AAATAACACT GTATTCCATA CATAGCCTGA TCACAGTAGT TGTTCTCTCT TATTTCCCAG AGTTTTTCTG CCCCTTTAAA AGAACCTCTG CTGTTCTGAT CCTTATCACA TCTCTGTTTT GACTGTTGGC TTTGTTGTTG CCAGTGTTCA GCCAGAACTT CTCTGAAACT TTTTTTTCAA CACATGCTAA GTTAATGGAA GTGTAGGAGA

GTTTTGATTC TCACACTCCT CAAGGCTAGA GCAGCTTTGG CAATTACTGA CTGAGAATTT TTCATTGCCA GTGATCAACT GAAAACTGGA GATTCCTTTG GAATTGTTAA ATCTGCTTAT AAATAAACAT AAATGCTTGC TCACACAGGC ATTCCTCTCT TCCAGAGCAC CCTAACATAC AGAAGAAAAC AAATAGGGAA TAACTATTAG ACATCTTCAT TCGTTAAAAA TCTACCAGAT GACTCTTTTA CATGGTGAGT TTCTATTGTG AATTTAAAAT CTTCCATAAT ATACAAGAAT TATGTTTACA TATCATATCT GACAAACATC TTTGTAGGAA TGCAAAGCAC ATCCATCTTT CTGTATTCTT TTCCAACAAA GACATTCATA AAATTATACC TTTGTGTGTT TGCATTTATG CTTTTATTAG TTCAAAACGT TTGGCCTCAT GGAAGTTTTT CATCGTGGAA ACCACATATT TCTGAAAAAA TATCTGACAA TATACAAACC TTCCATTCAG TTTTTACTCT CCAATTCTAC CATGTTTTCA

AAAAACAACT GTAGTAAAAA CACTCAGAAC TTTATTCTGG TTAACATCAT GCCTTGCTAG GGGACAATAG TTTCCCTTTT TGAAATAAAT TTAAAACAGA TGTAACATAA TTTGTTAATA AACAATGAGG GGGTAATCTA GAATAAGTAA CTTTTACCAT ATCATAGTTG ACAGCATTTA CAAGTTTTTT AAGTCCCTAC CACACTTGTA TTGAATGAAG AAGTATGGAA GATTATAATA TATTCAATGC AAGTAAAAAT ATCACAATCC TTAAGAACTC TTTAAGAAGC ACTGAATCCC ATAGGGATGA AAGTGATTAA ATTGTGCATA GTAACCCTCG CACAGAGCAT TCAGTAGGAT TTGCACCATT AACAACCCTC CATGCATTTG CCTGTGGGCA TTCAACATCT GTCATTTTTT TAAGTTATAA TATTTTTAGT CATTTTTTTC CTCTAAACTC TGGATAATTA TTATTCATTC TTATGACAGC AACTGTGTAA TCAGCTGTCG AAACACTGTG AAGGGCAAAA GAAAGAAAGC CACAAAATAT

TGTGTTTCTG TGCCAAGATT TTACAGCGAG CAAGGGAGAG TTAGAAAAGG AATTCTGAGA TTTCAGAGTC TTGGTCTCTT CACCTTTGCT TGGAAGAAAA TATCCTTTCC CTTCATTAGC CAACACTTTC TTGATCCTGA GAGTAGGAAA GGGAACACTG AGTCTTTTCA GTTGAAGGCC GTCCTTGCCT GCTGGACTTT GATCTATTGA AGTGGTGATG GGTGTTGCGG TTTCAGCCAT AAAGGCATCT GGCATAGTAG GCAAGAAGGG CCAGAGACCC GAGGAGAGTT ATCTGTCTCT GTTAACTTCA GTGTATCCCT CTAGTTCCCC AGATGCACCT GTTTCTGTAA ATATAAACAT GCATGTCATC AGAACACTTA ATATTCTGCA TACTGATCAT GACAACAAAA TGTACCTTCT AACACAGACA CTCTCACTAG GATAGACCAT GTAGGAACAT CGAATTCTAT TCAGTTAGGA CAGTGATGAT GTCTACATAT TATACCTCTG TCAAAACCTA CAGAATATAC AACACAGCAC AGAGTGAATT

CTAATGTAGC CTGTGGACAT TAATGAATAA TAATGTATCA ATATTGGCCC ATCAGTTGTA ACACTAATAT AAGATGTTAA TAACAGGGGG AATTGAAGGG GTGGTGGGGA GATATGTTGG AACTCTTTGT GCTTTCTGCT CAATTTTTCT GTAAACTTAA AACCGCACAC ACAAAAAAAG TTATTTTAAT TTTTTAAAAA GTATTCAGAG GGACTTGACC TTTCCAAATT CTCTCAAAGC AGGTCGGAGT AGTTAAGAAC ACAAATTTTA GAACCAGACT GCCAGAGTTT GAATCCTGGC TACACCACTT ACTAGCTTTG AGATTTCAGA CAATTTACTT AACTTCTCTG TCTCATTTTC TTCATCTGTG TGATAAGAAA TAAAGTAACA GGCCAGGCCC AGTGGCTCAC GCCTGTAATC CCAGCACTTT GAGAGGCCAA GGCGGGTGGA TCAGGAGTTC AAGATCAGCC TGGCCAACAT GACGAAAAAA TACAAAATCT CTACTAAAAA TACAAAAATT AGCTGGGTGT GGTGGCAGGC ACCTGTAATC

CCAGCTACTC AGGAGGCTGA GGCAGGAGAA TTGCTTGAAC GCAGGAGGTG GAGGTTGCAG TGAGCCAAGA TCATGCCACT GCACTCCAGT CTAGGCAACA GAATGAGACT CCATCTCAAA ATTAAAAAAA AAAAAAGTAA AAAGAAAAGA TAAGAAATAT AGTACCAGCC CCTATCTCAG AGTTCCTAGC TTAGAAAAAT TCCCAGAATA TAATAAGTGC AATGTAAGGG TCAGCTATCT TCATTATTAT TATCTATCAT AAATGAAATT ACACAATAAA GCTAGATCCG TTTCTTTCCT CTCCTTCTAC AAAAAATAAA GCAACTTTCC AGAACAATAC CCAGGTGATG ATTTCTCCCC TGCTCCCTCC CTAAGATATT GGCAAGTTTG GAGGGTTCAA GGAGAAACAG AGCATGTAGA GAAGATACCT CTCTCATAAC CATTTGTGAT TTACAAGTCT TACCTGATTC TTTTGAACTT AAAGGATGTA AGAAGGCTTT TGGTAGCTTC CATCTGATTC AAGGCTTTGG CAGCTGCTGT

GGAATACATG AGAACACTAG GTAAAGCACT GTCTTCCAAC ATGAAGAGAG AAAAATATGT GGAATGTTCA ATGGCATGCT TTGTATAAGA ATGCAACTTA CCTGGCAGGA ACAAATTTCT TTGCTGCAAA AGAAAAGACA AACAACCATT AATTCAGACT AAATGACTTT TAAGGATATA TTAAATCCAG ATACAATATG ACTTAATTCA TCAAGTGTTG CAAACTCGAT GCTTCAGGGC CTCTGTAATA ATCAGAGCAC AAGCATGGCT CTGTGGCATC TAGGGTAAAA TGCAAAGTGC ACAGCCATCC AAAGGGCATA GCAGCTTCCT AATGCCAGCA AATAGCTACG GGGTCATCTT GCCCAATTCA GCTCCCAATT TTTCATGAGA AGTCCAAAGT CTTAATTTAA ATGTGAGATT TCCTATTTTG TAAACGTCAG AACTTAACTC AAAAATGTTT TAAGTACTCT TAAACATGTA AGCCAAACAA ACCATGAGTG TAGTCAGATG TGCTTCCATA TTCCTTATGA GAGACTCTCA AATTTAAGCC

TGTACTCCAA ATAAATCTCC TTAGGAAGAA TTTTATCCAT TTTCCTTAGA GTGCTCATCA TGGCAGTTCC ATTGCACAAT TCCGGGAGGC ATCATATAAT TCAACATGAA TAGCACCCCC TGGAGTTGTA CAATATTAGG CACGACTAAC ATTTTTATTT CCTGAAACAC TTCCCACACT GAGTTGTACT ACTAACTCTT TTCTTAATAC TTCTGCTTAA TTATACTGCA TTTTATCCAG ATTCTAATTA TTGTTTAAAT CAGTAAGCAA GACCATGACT TATCAATGAG AAAGAAATGT ATTTTCAAAA ACATTTTTGA AGTACATTCA TAAACTTCCT CACCTTTCCG TAAGCATTTC CGAAGCCAGA GGAGAAATGG TGCTAATGTC AGGAGGGAGA GTCCAGCAGC AGAAAGTCCA GCTACCAAGG GAATGTTGGA CTCAGTGGGA GCTAAGGAAG TAAGAGACGA AGAAAGGTCA TGAGGAAGAA TTGATGTTAA AGTCTCTCCG TCCTGTCCCT TTGGCCTTTT TTCTGTACAT TCATTACTAG

GAGCAGAAGA GCTATCTAGT TTAATACAAG AAGCAGAGAT GTGGCATTAC AGGCCTTTGA GATCTGCTCC AAGCCACCTT TGAAGCTATT TCCACCATTG GGAGGCAGAA CTCTAACTTG CCAAGCTCGT TCACAATACC ACACCACACC TTGGTTAATA AACACTGCAC TTGCTTGCTC TCTTGCTCTC ACTCCCTCTT GTTTTCCATT TCCCCTTTCT CCTCTCCTCT CTCTGTCTCC TTTTTCCAGT TGTCAGAATT CTACCCTTTC CATCAACATG CAACTTCTGT TTTTTCTCTA TCCCCATACA ACTTAATATT CACAACTTGT CAACCTGGGC GAACTTTCTG GTTTGGATAT AATGAATAGT TGATTACTGT AACAAGATAG CTCCCCCTTT TTCTTTTTAA TCACCAGACA ACCACCATCA ATCAATGCAT CACCTTCACA GGTAGGTAGC AGGCCAGACC AGTGTCCTGT GGCTCCACAT GTCCGAGCTG CAGAGCCATT GAGCGTCCAT CCTTCAGGAC AGGCGAACTT GCACACAGTG

CCAAACACGG GCTCCCCACT GCAGCTCATG TTGATCTTTC CCGGAACTGC CAGGCTTGAA CATTTTACCA CTGCAAATGT TAGGTACACA GGCAGAGTTT CAGAAAAATC TACTGGAAAA CTTCCAAAAC TTGCTTAAAA GTCAACAATG AATGTAAAGT GTAAGCGCTA CTTAGTTTTC AGCATGTAGG AAATTAGGAC CAAACCCCTT TGGGGCAATC TAGGTTCAGA AACTTTATGA AGTATTTGAC CTGTACCCTA AAAAAGTCTG CACTCAATTC TACCTTGGCA GGAAGGAACC TCTTCTGTCC ATTGTCCCTG AGATGTGCAC TCAAGTTGAG TTGATCCATG TAATTCAAAT CCCTCCTCAC AGCTGAAGGC ACAAGAGGAC TTGTAGGTGA ATTCTCCAAT AGGGGAATGA GCACACCTCA CCAAACCCTT CGGGGGCTGG TGGACAGCAT CGCATCTCAC AGCTGGAACA CACGAGAGAG CACTTTAGAA GTTTGTTTGC ATCTCCAGCA ATACGTTTCC CAAGGTAACC AAGTTCCCAA

GCTCTTCAAT AGTTCTTTTT ATCTTAAAAT AAAATAAAAA CAAAGACTGT ACCTTCACAT GTGGGCTTCT CGTTGTCCCA CTCCCCTGTG GGGCCACATT GGAGCCTTTT GGATCCCTTC AACACAAAAC CCTGCTCACA GGAGAACTCA CAGCTGGACC CATAACGGAA ACTGCCAGAA GCACTAGGAA GACAATTCAT GTAGCCTCGC TCGGGGTTGG ACAAGGCTGT GCACTGGAAA GCTGAGACAT CAAAATGATG GTCAGAAAAT ATTGCAGTGG AACTAGAGAG TACTTGGCGT TTGTTGAGTG AACCCAGTTC ATTCAAGCAA CACTTGGAGA ACTGAAGATT CTTTATAATT CCCTGGACAA ATGGGAAGAT GGCTGTGTTT TCTTTGAATT TCAGCCCCCT CACTGATCAT GGCACTAATT AAAAGACTAA TTAATCAGAA CATTAGTTCC TGAGCACTGT TCTTCTAACA CACAAAATAA ATTATGGTCC AAGGAAAGAT TTCACGCAGT CTGAGGACAA CATATGGGTC ATGGATGTTT

ATAGATGGTG CCAAAAAGAA AGAAAAGAAA GCACCCCTAT AAAATTTGTC TGTTTTGCAG TTTGGTTTTT GTGTTATGTT TTGCTACTGG AAATCATTCT GTGCTGGCTT TGGCTAGGAC AAGGCCAGTG CCTGATAGTA AAAACTGCTT GTTTTCAATA TCCTTGCTCT CACTTTAAAG TGAATTAAAA TTTACTGCTT ATATATGCAT CAATACTATC TCTGTAGCTG ACACCATGCT TGAAACAGTC TCATCACTGC TAATTATGAG CCATTTCAGA AGACAGGTGT GATGAGAGTT TTACATTCAA ATCATGTTCT CATTATTCTG CTTTCCGAAT TTTCTAATAT GATTCCTTTA GATTAAGAAT TCTGTCTATT CCATGCTAAT GTCTACAAAG TTTTATCAGC ACATCACAGT TAAAAAAAAA CAGCAAAGAA TTCATTCTTA ACACATATGA TCCTTTCCCT GGCCAAACAT TAGTTCTTTT AAATGAATCT CAAAGATACG AGGGTTGCTC ATCAAATCTG ATTTCTATAG TTAAAGTGGG

TATTGGTTTT TTTTTTCACT GTCCAAGTTT GAAGATGGTT GTTCTTTAAG AAAGTATAAA TCGAAGGATC TCAAGCTTAC CTTCACAAAC TGGGATTTGC TGTGTCCACT GCCCTTGAGT GGTGCATTCA ACCTGGGCTG GTCCCTGCAA CATGAAGCCT TCCTCACAGG TGAAGTTGCA GGATGATTTG AAGGTGAACT CTCCAGCAGG GGAATGGCTG CACCTCACAG AGCCATTCTG AGGCTGGCGG ACGGCCCTGC ATGTCACAGC TGTAACAAAT ATACGCATTG ATATTAGCAC GGCCTAGAAT TAGCTTGCCC ATTTCCAGTA TGGGTTGAGA GAAAGAATGT TCACAGTAAG TCTCCATGTG GAACAACTCT ACCTTTACAC GTTGGCTTCT CGTTGTCCCA ATTCCCAGAT GAGGTACACT GAAGGCTCTG GGCTCCCATT AGTTCAAATC CTTCTTCACA GTCAAATGTA CAGGTTGTGT TCCATGGGAA GCTTCCAGGG TTTTGGAAAC ATTCCACGAA CCCATTGGCT GGATTTGTCA CAGCATCACA CTCAACCACT GAGGATTTTA AAGAGCACCA TGAATTTTAC AGAAGAATGA TCTTTTCACT TCCTATTGAG CTGGGTGCCT AACAGAGTGA GGAAGCTGCC TTCAAAGGGT AGATCCCAAA GTCCTATGTC AATTCTTAGG GACATGCACA GCCAGAATAA AAGCTTTTAT TCTTTTTCAT GGATATTCTA TCTTTTCTGA TTTCCACTTT GCCTATGCTG AGTGGTCTCT AATCTATGTT ATCATTTACG TGAGGTAAAA ATTTAAAAAA AATAGATTCC AGATTAGGAG TTATGACTAG TACTGACATA CGTAGGCTAT TCATTTATTT TAGCCCATCA GAGCCTGAAG AAGTGATTTT TCTTTTTTTG GCCTCTGGTT CAGAAAGATA AAATTAAGAG AGAAAAAGAG ATACTAAGAC TGCTTGACTA

TCATGGTCTT AAGTTAGTCC CATGGCTTGG AAAAGTTAAA CAGGGAAACA AGATGAGAAA TCCATTGAGA TTTCTAGAGC TTTATTGTTT TATGGTCTCC CTTACAAATC ACCAGAGCCT CAGAAACACC CATTTCAAGC ATAGAATAAA AAAACCTCTC TCAACCCAAG CAGGTACTGG GTTGGCAATA TACATTGGCT GAGAGAACAA ATTGTATTAA AAACAAAAAC AAAAAAAAAA CTTTCCCTGA AGTTTTGAAA ATGTAAGTTG AATCAAAAAA CAGAAGCAAT GAGGGATGAG TTACAGAACG TTCTGTGCAT TCTCAGAGGG ATTTACCATT GCAGGCTGGA ATAGGAGCAC TCCATTCTCC AGAGGACATA CACTGCATGG TCTCCATGCT GCTTGGCAGG TAACCCCTAT CACAGCTGAT AGAGCAGGAA GAATTGTAGC TGAAGTTTCC CAGTGGGTGA CTGCAAACCA GGCTTCCATG CTCAGGGGAT TCCAGGGCTG TACAGTTCAC AACTGAAAAA GAAACCCAAA TCAGTTCTGC

TCATCTCTCA CCTTTAACAG ATAAGAACAC TGGAAACTAG AACTACAGTT TGGTTTTTTT TTTTTTTAGT TTAAAAATTT ATAAAATTTC TAATGGAATT TGTAAAATTG ACTGTAATTC TACCCCTTTT CTTTTATTCA AGAAAATGCT GATCCATAAC AACAACAACA AAAAAGCAGT GATGACAACC ATAAAAAAGA AATATTGAGT GATATGGGGA GAGTAGTGTA ATTGTGTTTA CCTCAAAACT GTTCAAATTA TATGAACAAA CACAGCAAAC TTAGGTACCA CAACAAATTT CTTGTTACTT TTCTCACAAC TGCTAAAAAT ACTACAGTAA GCTTCCAACC AGGATGAGAA CCATTCACAA AGCTATATTT CAAATTTAAG TACTAGAATA CATTACAAAT TTTAAAACCC TAATGCTGCA CTGTCTACTA TAGTAGCCAC TATCTGTGTG GCTACTCAAA TTTAAACTTG AATTCGTTGA AATCAAATAA CATTTAAAAT TCAGTTCCTC AGTGTCACCA GCCACATTTC AAGTACTCAA

TAACCACATG TGGCTCATAG GTACACACTG GAAAACACAG CTATGGAACA TTTCCATTAT CACAAAAGCT CTACTGCACA ACGCTGTGCT AAGGAATCTT GGAGAGAAGC TCATCTAACT CTCTTAATGT ACAAATTTAG GAACTGAGAC CTCATTTCAT TCAAGTGACT TGCTCCATGC TACACGGCTA GTCATTACAG AGCCAGAGGC CAGAGCATGA ACCAAGATAC CCTGGACTCT GTAACTCACT CATTTCTACT GCAACGTCTT GTTACCACCT AGATGAGGTG AGTACATGTT CCTCGCAGGG ACACAGAATT ACAGTTTATT GAATGTGTCC TGTGTGCCAG GCACCATGTA ACCATGAGCC TATGAAGTTC ACACTATTAT TATCCTCATT TTACAATGAG AAAACTGACA TAGAGAGTTA AACTATCTTG TCAAGGTGCC AAAATAAATA ACTGGTGAAT CTAGGACTCA AACCCAGCAG GGTCTGACTT CATAGTCTCA GCTCACGATC ACCATATGAC ACCATCTGCA CCAGGGAAGG

GAAGGCATGC AGACCTGACT CTAATGCCAG CTAGGACGTG AGATGGTGCT ACCATCTCAA GTGAAGAAAG AGGCAAGAAC CAGACTTACT TTGCTCACAC TTGAGTCCAC TGAAGCCAGG GTCACACTTG CAAGTGTAAT TATTGATGGT CTCTACACAT TCACCGTGGC CACTGCAGGA TGTATTGGTA CAGGCAGCTA CGGAAAATAC AAAGCATGAT GAGGAGGACT ATTACTGTGC TTATACTGAG TGCCTTTGAT TTTAGAATCA ACAGTGTGCA ACAGAGACAT CAGCAGTCCT ACAGAGTGCC ATAGACTTTA ACTGAAGTGT TTTACAAAGT TCCAAATCTG AGTTTCAGGC CCACCTATCC TAAACCTTGA TGCTAATGTA TAGCTGTGGC TGGCACCTAC CGTAGAAAAT TTACTTCTTC ACAAACTCTG AAGACAGTTC CCCTACCACA AATAAACAAG TAATTAAAAT ATGTATTGTG TGTGTGCATT TTTATATGTA AAGAACTACA TATTTGCCTA CAGTATTTAT ATATATTTTA

TATATATACA TACACACATA TATGTGTGTA TATGTGTGTA TGTATATATA TAAAATGTAT ATAAATGCTG TAGGCTATAT ATATATACAC ACACACATAT ATGTGTGTGT GTATATATGT GTGTGTGTGT ATATATATAC ATATCCACAT ATTCTTGCCC ACATTCACAC AAAACAGCAA AAGAGAGAAA CTTTAGCAGT TAAACAGAAT CTTTTGGAAC ATAAAATGAC CACAATAGAG AGCAGTTTTT GCATGCTGTA AATTTGCCAA GATGCCCACA CACTGAAACT ACCTCCCACT GCTGCCGCAA ACTCCCTACC TGTGTAGCAT AGGGCAAGCT TCTTCTTGCT GCACCTCTCA TCATTCCACA TGCCCACATC TTTTTCTCTC TTGATGTAGA TCTCCACGCA GTCCTCATCT TTTTGCCTAT TGTTGGGTTC ACCTGGAGCC CAGTTCTTGG CTTCTTCTGT CAGAGGTTTC TGGGTTCCTA CCCAGACCCA CACATTGTTG ACTTTTCTGA TTCCAATCCA GTAATAACTT GGTGAATAGC

TCAATATGGA GTTTAGGTAC TCAATCTCTT CTTTGTTTTG AATTGCAACC AGGTGTGTGT ACCTTTGCTG ACAATAAGCA CTGGCCTCAT CATAAGTCAT AGCTTCCGTG GAGGTGTTGT AAGACCAGGC TCCACTCTCT TTAATGAGAA GCACTAGTGG GAGAAAAAGA AAAGAAATGG TAGAGTTTGG TACTGTTGTG GTTTAACTCT GACAACTGTG CTTTTTATTG TCTTATTTTT GGCAATGTTT GTGACATGGC CCAGACTTTT CTCATCTTTT CAAAAGTAAG AAGTACGTAT GAAGAAACAG CGACTTATTG TTTATCTCTT TTGTGACTGC CACCCACTAG GTACCTTATC CACACTCACT CACAACATTA TAGTATACCC ATTTTGTAGT AGAATAATAA TCAGAATAAC TAAGCTTTAT TGAGCACTTA GTATGCACCA AGAAGCACTG TATGAGGTAC TTTCCATGAA CCATGCTATT GAATCCTCAC AATGCATCTG GGAAATAGGT CATTATGATC CACACTTTAC ACTTAAGGAA

AGGGAGACAC CAAGAGGTAA AGTAAATGAC CCCAAGCCCA GGGAAGAACA CATTGCAGGT AGAGGTCAAG GATGCTGCCA GATATCCTGT GCAGGACAGC CCCAGACAAG CAAGGATATT TCAGTCTGAA ATATCTATAG TGCGAGAATG AGAAATCTTG GTCTAATGGC ACTGACTTAC CCAAAGTGAG AGCTGAGAGA AACTGTGAAG CAATCATGAC TTCAAGAGTT CTTTTCACCC AAAGGTTTAG GCTTGAAATA CTTTCCTGGG GAGATAAAAC ACAAAATGAA TTAAAGAAGG AAATCGTGGG TAGCTAGTTA CATTATTCTA CCATGATGTT TAAGGCAGCA TCCTAAGATT TTGGGCAAAG GACACTAGTG CAATAATCTT TATTTCAGAG TTTAATCAAA TAAATAAACA AATTTTAAGA CTTTCATTAT TTAGGTCAAA GAGAAAAGAC AGGTTTTAGC TACAATACAA TAAGAGCTTG TACAGATGTG GTTTTTATTA GAAGGCCTTT TGCATATCTG TGTTTCATGG

CCCGAGGCTG CCCTTATAAA GCGTTCTGCA CTTACCGTTT TGGGAAGCAG TTGTTCAAAC ACAGGATCTC TCAGGTGGGT ATCACTGCTG CCTCTGTCTC AGGTCAGTAT AGGAGTTTTG ATGTGAAGTC AGCCAAGAAC AGCTGAACAC TACTTCGGCT GAGGCCCTTT TATAGGAGGG ATTGCTTCCT GTGAATAATA GGAGGATATT GTCCACATCC AGTAAAGAGG AAATCCCCAA TGGCATCCAA AAACTTTCCC GGGAATATCC ACGATGCTTA AAATTACAAT GATGTCAGAA ACTCTGTCTC TTGAAGCTAC TTCACCTTTG TCCATGCCTT TATATCGTAT ATGCAATTTT ATTAATATGA CAAAAATGCA TGATTTTTAA TTATAATAAC ATAAAGTCTA TGTCTTTAAA AAGTTGTAAA ACTTTGCTTG TTAGTAGTGT CTCTCATGTA GTTGTGGTAG TAATTAGAAT TTCAGAAACA GAAGGAAACC AAGAATAGGT TTGTCATCCA TAGTCTACTA CCTTCAATTT CTCATTCATA

GCTGTGGATA ACCAATCACT ACTCATTTTT TCTTCCTTTT TCACCTGCCA ATTCAACATA TTTAACATGC ACTGTCTCAC AGAGGAATGA CTCACAAGGT AGATATTAAT CTTCAGATTT TGCACGGCAG TTATGCCTAA ATTAAAATAT TATCTAAAAA TAATATCTAA CACTCAAATG GTTAAAATAA TGCCTTATTT TAAAAAAAGA AAAATGGGAA ATAGATATTT ACATCTGGGA AAGTTTCATG GTTTGTTCAG TGAAAAAAAT AAAAAGGAGG CCAGGCACAG TGGCTCACGC CTGTAATCCC ACCACTTTGG GAGGCCGAGG CAGGCGGATC ACCTGAGGCC GGGAGTTCAA GACCAGCCTG ACCAACATGG AGAAACGCCA TCTCTACTAA AAATACAAAA TTAGCTGGGC ATGGTGGCGC ATGCCTGTAA TCCCAGCTAC TCGGGAGGCT GAGGCAGGAG AATCGCTTGA ACCCGGGAAG TGGAGGTTGC AGTGAGCCAA GATCACGCCA GTGCACTCCA GCCTGGGAAA

CGAGTGAAAC TCTGTCTTAA AAAAAAAAAA AAAAAAAGAA AAGAAAAGAA AAAAAATAAA ACGGAAAACT ATATATATAT ATTTAATTGG TCAAAATTTT GTTTAAAATT TTTGAAATGT TAATGTGCAA AGAATAAAAA TTCTTCCACA ATGTTAACAG TGACTAACTC TGGATGGCAG GATTTGGGAT AATTTTTATA TCCTTCATTA TTATTTTCAG GATTTTAAAG TTTTTTTCAA TTTCCCTTTT TTTCACCTTT ATAGTAACAA GAATACAGTT TAAAGAAACT TGTCTCTAGG CCAGGCATGA TGGCTCATGC CTGTAATCCC AGCACTTTGG GAGGCTGAGG TGGGTGGATC ACCTGAGGTC AGGAGTTCCA GACCAGCGTG GCCAATATGG TGAAACCCTG TCTCTACTAA AAATACAAAA ATTAGCCGGG GTGTAGTGGC GCATGCCTGT AATCCCAGCT ACTGGGGAGC CTGATGCAAG AGAATCGCTT GAACCCAGGA GGCAGAGGTT GCAGTGAGCT GAAATCACAC CATTGCACTC

CAGCCTGGGC GACAGAGCAA GACTCCATCT CAAAAAAAAA GAAAAAAAGA AAAAGAAAAG AAAAGAAATT TGTTTCCAAA TGCAACAGAA GGAGATGTAT GTGGTATCCT ATATTCCTGC TCTTCATTTT GACATTTCTT CTGGGTGATT GTATACATTC CCCATCTCTG CATCTTACCC TATCTAAATG ATGGTAACAG TAAATGGGGA TCATTTTAAT TTCCATATTC TGTAGGTTTT CAGAGCTCAA GTCAAGCTAA TATTCTATAT CTACAGCCTT TCAAAATAGG AGGTCTATCT AAAAATGTAC TGTCAGCAGA CCTGAACGAG TAGTGGTAAA AGCCTCGTTT TTCTCTTTAC TTGTTAGCAC TGGTCTTTCT GTGTTCATAA AGATGTCAAG ACCCAAAAAA AAAACAAGAA AAGAGAAGAA AAATTCCAAA AAAGACAACT GATTAGAAAA AAATAACTTA ATTAACGAAT TTAATTCAAC CCCTATCAAA AAGCATAGAA TTTATTCCCT CCACCTTACC ACTCTCTTAC

ATGATCCAGA TACTGACATT ATTCCAATTC TTTATCCCAC TTTACTTAGC TCAATGTGGT TGTTGCTTCA ATAAATTCAG AAGAGTAATC ACTCATATAG TGTTTATTTA GATTTTAGGG CAGAATGTCA AGTTGGGTTA ATACATTATC TGTATGTATT TTATTTTTAA TAAAGTATGA ATACATAATC TGCTATTTTT AAAAAGCATG GTCAAATGTA TAGAGTAGCC AAATCTTAAA AAACAATTTA TCTTCGATAT CAATAAAGTA CCTAATAATT ATATTGCTAA TAGAAATTAG TCGTTAACAT CCCTAGATAA CTAACTTTAT TATTGCGAAT TTTTCATAAC TAAGTTTATA GTTTATCTCT TCCCCTTTTT AAAATTAGTT CAAAGATATC TAAAAATAGC CCCAGTGGTG ATGAAGTTTC TATTTTACTT ACATATATAT GTCCTGGACC CCCAATTATA ATCTCTAACA TTTATTGAGT GCTTACTATG TGCCAGGCCA TATTCTGAGC ATTTTGTATG TTCACCTATT GATTATTCAA

TCCGTACAAC AGCCTATGAA ATAGGTACTC CTATTATCCC CATTTTACAG ATGAGGAAAT TGAGAATCTG GGGATTTTAT CTCATTCAAA AGCACAGAGC TAAGGGTTGA AACCAGGCAG TTGATATCCA GAGCCCACTC CCTTACCTGC TACTCCAAAC CATGATTTCT TTTGTTGTTA TGCCCCGAGA TTCCTTGTTC TACCCAAGTT TCCTGTACTC TTCTTGCCCT CTTCTTCCTG AGACATCCTT GACCATCACA GCTCTCCACT GAGATAACTG TGTCCTGGGT TCTGAGACAT GGGGGCTGGA AGGGACCCCA GGGACAGTGA GCAGTAGGGA GAGGATGCAG TGAGAACAGA CCCTGGATCC CCGGTGCATA GGCAGGGAGA AAGTGGACAA AGGAAAAAAC AAGCAAGGCA GGTGGAGCCA TGCCTAGGTA AAGTTGATCC CTAAGCCACA GTTCCCAGAA GTTCCTGATT CAAAAGCAAA TTTTCTCTAA GGTCAAAGGG CAAACTGATT ATTCTAAATT CTAAACTGAT

TATTTCTAAA TTGAGAAAGC TTCAGGGAGA GATCCCAATA TTCGAAGGAT AAGAGAAATG AGGAGTGGAA GAGATAGGTG AGTAACAGTA ACTTAAATGT AGACTATATA TAATATATAA TATATGTAGA GTATATATAT ATAATTACAA TATATTATAT ATGTGGAATA TATATATTAT TTATATATAT TTATATATTT TATATATATA GATATTTTTA TATTTTATAT ATAAATATAG ATATTTTTAT ATTTTATATA TAAATATAGA TATTTTTATA TATATTATAT ATAAATATAT GTAAAATACT GTGAAAGAAG AATAGAATCT TGAGACCTCA AATTCACTAT GCCAAAGGGA AAGTTAAGCT TGGGAAATGA GTCATGCAAA AACTGCCTTC CTTTTGTTCC CAAATACCTG TAATTTCACA TGCTTACTTT ATCTTATATA AAATGTAGAT GTACTGAGCA TGAGATCCAT GCATAATTTC CCTCTAGTCC CTTCTTTTTA CATGTAAAGT GTAGACTCAC TGAGTGTTAC AGAGCCTTGC

CACAATGTAA ACACTTGTCT CATTGCCAAC CCATCTTTCG TTTATTTTCT TCCCCTCCTG CTTGCTCTTT CCCCTCTAAA GATGGAAGTT CCCAAAACTC TCTTTGGAAA AAGCGCAGGT CACAGATCCT ACAGTGATTT GTGTTTCTTT TACCTGGGAC AAAATAAACC TCTAATCTGT TGAGATATGC TTCAGTTACT TTTTGGTTTA CAATATGTAC ATGTATGTAT ATAATTTATA TGTATATAAT ATATGTACTT GTTTTAACCA GAGGTATGTT ATTCAAAATC CATTCATCCT TACAATTACC TGCATTCTCC CACAGTATTT TCTGTGTCCC TGCCCCCGAG GTTGTCACTG CAAATCAGGT ACATGGATAC TGGGAGCTGA TGGGCTCCCC TCTGGCTACC TGGGCTGCTG AAGGGGCCAT AGACAGACCC AGCTTTCCTC TCGTGGAGAG GCCCTGGGCC AGCGCTGCGT GGGAGTGGGA TTACAACCAG ACTATAGCTT CTTCACCTGC TTTTTCCTAT CAGGATTTCA TAAGAGGCAA

TTGCTTGTTT TTTGAGGGTG GGGGCAAATC AGGGGGAGTT GAAGAGGAAA TTGGGTAAGA TTTGAATAGT TGGGCATGTT GAATATTATG AATATCATCT CCCTCTTCAA ATAATCCAAA ATATACCCCC AAGAAACAGG CTGATTAGAG GTGCTTCAAG GCTCCACTGA ATCTCCCAAG CTCTGAAGAT GTAGCTAGCT GTTACCGGAT TGCCGGTTTT CAAGCCTCGC CTCACATGGA CCCTCTTGGC AGTTTCTCGC ATGGGGGAAG CATCCGCTAC ATAGATGGGA ATGAAAAGAG GAAAGAAGAC GGTGCAAACT CAGGCACACC CCGGTGTCTG CCACCAGTGC TATTTAATCT CTGAGGTGTC ACCCTTCCTG GCTTTATTGT CTCTTCCTGG AAGTCTCTTG TCCTCTCCTC CACACCCTTT AATCAGGCAT CAAAGACTTT AACCAGTTTT GCTGTGTGCC CAGGCCCACT CATTCTCACT TTTATGGCAA AGGGAGTGGG AGACAGAGAG ATAGCCAGAA AGAAGAGATT GGGGACCCCA

AGACAAATGT TAGAATTTTA ACCAAGGCCA CCCTGTGGAC AGGAGATTAT TGGGTTTAGT GGAAAGCAGC ACTGGCCACA ACCACACGTG GCAAAAGCAT CTATCGAGGA GTGAAGTTAT ATTTGGTGAA TGTGACCGGG AAGCAGGGGC AGTGGTGTCC TCCTGCCTTC CTGAGGCACT CTGTTCCCTT ACCTCTGCGA AGGCTTATTT TACCCCTGAG TGCTTAGTTT TGAAAGCCTT AGTTCCCTCT CTCCCATAAA AAAGCTCTAC TCTGCTAACA TCTAAGTTAC CTTTGCAGAG TCTTAGGTAG AGGGAGGAAA TCCCAATAAA GATTCCACCC TATCTGCAAA ATACAAACAT GGTATTTCTT GCATTCCCAA AATTGTGAAA GAAAATGTGT ATCACCACAG TAGAGAATGG CATTTTTTGT TTGATCAAAA CCTAAATATA TTTGATGAAA ATGTGTCTGG TTCTAAGTTT ATTTCCCAGA AAGCCATGTT TACTCACTTG GAATTTATAG ACATCTTATA ATATCTGAGT CGAGTAGGAG

CTCCGGGCTC TACCTCACTC TTTTCTCCCA CACCCAGGGG GAAGTGTAGG GTTCTCAGAC TTTAGAATAA AGAGGAATCA CCTGGACAAC TCACCTAAAA TGCACATCTT CAGGTCTCAT ACTCAGAGGC TCTGACTCAA CAGGTCTGGG TGGCGCCCAA GAATTTGGGC TTTAAATGAG TATCTCAGAT GATTCTAATA CAGAATGTGT AAGATGACCA GATCCTATCA CACTTAGATG TATTGGCCTA GGGCCACCTA ACTTGGAGAA AATGTTAGTA AGACCCCGTG GTTGGTGCTC AGCTATAGGT ACCAGAATTT TGATCAAAAT TTACTATCAT TGTGACACTT CTCTTCGGAA CTGGAAGGCC AGAACCCCAC TTGTAAAGTG CTGGGAAAAT ACAAGGAAAA TTTAGGGTGA GTAGCATTTT GAATTCTTAC ACATGGAAAG TAAATGTATA AGAATTCTTA CCAATAAAAA AAAAGCAAGA GAGAATAGCT GCTAAAGAAT TAACACAAAT ATGTATATAT TAGTTATTCT CTTTTCTCCT

CTGATTCCAG AGGACTTTGT AATTCCACTA ATTCTTCTTG AGCTTCCAGG ATGATCTGAG ACTTGAATTT TTCATGTGCT TTTTGCTTCC TATTTGGCAG CATCTTATCT TGAAGTTTCC GCTTTCTGCT TGGGGACCTA AAAACTAACT AATGGGAATT TCTTCAAAAT GAGCAAACTC TGGTGAATTC CCAAAGCGGA AGAAACAAGT GAGGATCGGG CTGGTTAATT AAGAGAACTT TTCCTGAATG TAGCCAGACT GTTTGCCGAC TGTTGTTAAC ATGAGGGAAG AAATACCCCT GGATTTTAGA AGAGCCCCTT GTTTGTTTTC CTTGGCCATT TGTGCTGCTT GTTTTGTAAG TCAGAAATTT CCTGAAGGAC TATTATTAGC TTTGTTCTCA CGTCAGAAAA CTTCTGCTCT GGCCACTTTT AAACATATAA CTTGGATTTT ACTGTATTAG AAAATGTAAC AATTACAGAC AGCACTAAAA GGACACCAAA GGGCAAAGAA AATGGGTAAC TTTTTTTTCT TCCCCAAATC TAAAATAGGT GATTTTGGAG AAGTAGGAGA AAAACCTGGA TTTTCTAGAT CTCTTTAGAG CTCAACAACT GATATAGTTA ATTATGTAAG TCTTTGATAT TTGGAAATGA TTGGATTAAC CGGATAACAA TGAATATTTA AATACAGTGA TTTGGCCAGG AGCAGTGGCT CATGCCTGTA ATCCCAGCAT TTGGGGAGGC TGAGGCGGGT GGATCACCTA AGGCCGGGAG TTCCAGACCA GCCTGGCCAA CATGGTGAAA CCCCATCTCT ACTAAAAATA CAAAATTAGC CAGGCGTGGT GGTGCAAGAC TGTAATCCCA GCAACTCGGG AGGCTGAGGC AGGAGAATTG CTTGAACCCG GGAGGCAGAG GTTGCAGTGA GCCAAGATCA CGCCATTGCA CTCCAGCCTG GGCAACAAGA GCGAAATTCC ATCTCAATAA ATAAATAAAT

AAATACAGTG ATTTAACACA AGAGATTTCT ATTTCACACT AATGAGCTCT GTCACTGGGG CAAGCTTCTT TGCCTCATTA AGTCTCAGAT TTCCCGAGAG CTTATTTATT TATACCAAGA GTGCTTTACT ACCGTCTCTG CTAGCTGTGA CATAATATGA CAAAAGGTAT AAATATGGGA AAAGGCACTA ATTTATATCA AAGCGTTCTT CGTTTTTCCT TGCTGTGAAG TTTTTAGCTA ATAATTCATA AGAATATACC ATATTTAGAG TGTTTACTAT GCATGGGCCT GGCACTTCAC ATACATTGCT TCTTACAAAT TTTACAAAGT GAAAGGTAGA TATTAATCTC ATTTTATGGA GGACAAGATA GAGATCTGGA GAGGTTACAT AACTTGCCAG TGTTTTTTCA GTTAATAAAT GGTAGGGTGG AGATTCAATC TGTGTTACTC TAAAGTCCGT GTCCTTTTTA TTGGCTCCAT GCCTACTCAG ATTTAAATCT CAGCAGGGAA GTAAACCTTA GTTTTTACAT GAGAAAATGT TACAGCAGCC

TTCTCGGCTT CCTTTACCCC CATCCCAGTT TCACGAGCTT AGTGCCTTAG ATCGGGTTCC TTTAGAAGCA GACCTCGAAA TAAGGATGTG GGTGCCAGTC ATTTATTGAA AAGATGATCC CAAGAAAGCC TAGTAGGAGA GTGAGGAAGT GAGATGGGGA AAGGAAGAAA CTCCACAAGA AGTGTGTTAA TAAGCAGGTT ACCGCTGTGG GCAGCCATGG GGCTCAGCTG CACTAACAAA CTCTGTCTAG TACAGAAAAC CTCAGGGTCT CCCCAAGGAG GGGCAAGAAG TCTGCCTAGG GTATATATCC GCCAACTCAG TCACTGGCTG AGAGCTGATC CTGGGAGGGC ATGGTTAATT CCTCTGCACT TTCAAGTGGA TTCCTGTGGT CAGAAAAAGC CCTCTACAAT GAATTCCAGA TGCTTGTATT TAAATCTGAC ATGATCTGAA TGCTGTGTTG GGACAGGGTG GGCGTTATTA GTTTTCTGTC ATTACTGTAA CAGATTACTA CAAACCTGAT GGCTGCAAAG AACACATATT

TATTATGTCA TAGTTTGTGT GGGTCAGAAG TACAGGTTAG CTCAACTAGT TTCTCTGCTC TAGGTTTCAC ATTGCCAATA TCAAGGTGTC ATCCAGTTGG GCTCTTCTTG GGAGGCTTGG GGATGAATCC ACTTTCAAGC TCATTCAGAT TGTTGGCAGA ATCCAGTTCC TTGTGGTTGC AGGACCAAGG TCCCTGTTGC CTTGCTGGCT GTTGGCCAGG AGTCATTCTT AGCTTCTAGA GACTACCTGT ACTCTCTGAC TCGTGTCTCC ACTTCACCTT TCAAACCAGC AGCGGCTAGT CGAGTCCCTC TCTTCAAATG TCTCCAACTG TGCCTTCACC TCATTTCTCC TCTGTGTACC ATGTCTGCCT CTACTGCTTG TAAGGGCTCA TGGGATTACA TTGGATTTAT TCAATCCAGG ATAATCTCCA TATTTTAAGG CTAGCTGACT AGTGATCTTA ATTCCATCTA CAAAGTCCCT TCCAATAGTA CTGTATTAGT CCATTTTCAT GCTACTGATA AAGACATACC CAAGACTGGG CAATTCACAA

AAGAAAGAGG TTTAATTAGA TTTACAGTTC CACATGGCTG GGGAAGCCTC ACAATCATGG CAGAAGTCAA GGAAGAGCAA GTCATGTCTT ACATAGATGG CAGCAGGCAA AGAGAGAGAG CTTGTGCAGG GAACTCCTCT TTTTAAAACC ATCAGATCTC ATAATACTTA TTCACTATCA CAAGAACAGC ATGGGAAAGT CTTGCCCCCA TGATTCAATT ACTCCCACCA GGTCCCTCCC ACAACATGCA GGAATTCAAG ATGAGATTTG TGTGGGGACA CAGCCAAACC ATATCAAGTA CCTAGATTCA TGTTTGATTA AACAACCAGG GAGCAGAAAT CTTCAGGAGT GGGGGGCATC TTTAGAATTC TGCCCACCAA OGCTGGGCGC GGTGGCTCAC ACCTGTAATC CCAGCACTTT GGGAGGCCAA GGTGGGTGGA TCATGAGGTC AAGAGATCGA GACCACCCTG GCCATGGTGA AACCCCATTT CTACTAAAAA TACAAAAATT AGCCAGGTAT GGTGGTGGGC ACCTGTAGTC CCAGCTACTC

AGGAGGCTGA GGTAGGAGAA TCACTTGAAC CCAGGAAGCG GAGGTTGCAG TGAGCCAAGA TTGCGCCGCT GCACTCCAGC CTGGGAGACA GAGCAAGACT GTCTCAAAAA AAAAGAATTC TGCCCATCAT AGTAGGCTGT CCTACAGAGA CATAACCCAG GAATTAGGTG AATGGCTAAC CTAAATTAGC ACTGTGATGT GTTTTCTGAC TTGGTCCTTA TAGCTCCTCT GCTTAGATGT GGAACTAATC CATGAATGCA AGGGTTTGTC TAGAGTTTTA AGTGGGAGTT AAATATCCAA AGTACAGGAG ATATTATGGG TGCCTCATCC ATGTCCCCTT GGCATTTATC TTTCTTGGAT AACCCAACTC TATTAGTTTT TATATCTCAC TTGTTCCTAT ACTCTGTGAA CTGATGTCCC ATAAATAGAC ATTTCATTTT GCCAGTCTTC TTGAACAATA ATTACGATTA TTAATCTAGC AGTTATCATT AATTGGCCAC TTCACATTAG ACACAGCACT TAGGACTTAA GAATACCATG

TCATTTGATC ATCATAATAT GGTCAGGAAT TAAGTATTGC TATCCAAATT TTACAAAGAA GGCACTGAGG GTTAGAGTTT AAATAACTTG CTTAAGATGT CATAGCCTGT AAGTGACAAA ACTAGGACTC AAATACAGGT CCATCTGACT CCAAAGTCTA TGTTCTTGGC TACCACACTG CCTCTCCTAC AAGTGACCTG TGGTTTTACT ACTATATTCA CACTCTACTA ACTTTACCAT CTCCCATGAG TCTGTCTAGA GGAGGGCACA CACAGCACAG AAAACACATG AATGCAAAAT AAGGAAGGGC CTACTTACTA CACAGAGCCA TTCTAATACC TGATGTTTGC TCTAATCCAG TTTTACTATT AATTAGTTGC TGGTGCCCAA GTTTTTACTG AGAAATGGGG ATAATTTTGG AAGTCATAAT GATGCCTTCT TCTCATAGGG TATTTTATTT GTTGTTGTAT CTCCAGGCCC CAACACAGCC TGGCTTTTAG TAAATGATCA AAAATACCTG TTGAATGAAT AAATGGAGTC ACCTGAAACA

TGTTAAACAT TTGTTCATGT GTCCTAATCG TGGATTTCAG GATAGTAAGC ATCCTAAAAG GAAAGCATGC ACACTGTTCT TGCTACATTA ATTTCTCACA ATATAAAAAA AGAAAAGCAT CTGAAAAAAG CTGCCAGCCG CTGTGTCTCC TAATATCAAA CTGAGCACAG ATATGGAGAA GCTAAGGGAG AGGGATGATG GGCCATGCCT CTAACCTCAT CATGGCAAAA GTCCTGGGGG TCAGACCCGA GGAGAGCAGG AAGTGTCTTT TGAGGGATAC ATTTCCACAG TGGAAATAAT GAGACTTAAA TAAATATTAT ATACACAGTT CAACTGTTTT TATGTGTAAA GGTAGTAGGT TTTCACAGTA AGGAAGCACT TCTTTTTTTT TTTGTTTGAG ACAGAGTCTC GCTCTGTCTC CCAGCCTGGA GTACAGTGGT GCTATCTCGG CTCACTGCAA TCTCTGCCTC CTGGATTCAA GTGATTCTCC TGCCTCAGCC TCCCGAGTAG CTGGGACAAC AGGTGTGTGC CATTACACCT GGCTAATTTT

TGTATTTTTA GCAGAGATGC GGTTTCACCA TGTTGGCCAG GCTGATCTCG AACTCCTGAC CTCAGGTGTT CTGCCCGCCT CTGCCTCCCA ATGTGCTGGG ATTACAGGCA TGAGCCACTG CACTCACCAA GCACTTCTAC TGATAGCATT TACAAACCCT TCTTAGAATA TTTAAAAATT CTAAGAGAAG AGTAAATTGA GCCTTCCCAA CTAATACTAG GAGGTTATAA CCTTCATACC AAAACTGGAC AATGCTTGCA CAAAAGAAGG AAGCCAATGA GGCCACCTAG AAGGAAGACT GGGCATTGGG CCCAGTGAGT CCTGGAAACC TCATCTGTGC CAGCCACCCC GGCATGGCCT GTATGAGTGG ATGAGGGTGA CTTGTCCACA GACAATAGCC ATCTAGCTGT GATAAAGGAG TCAAGGTAGT CAGCTGCATC TCTTTCACCT GTTTGCCAAT GTTACACAGG TTGAAAAGCT AAGGTTTATG TAAAGCAAGC ATCAAAGATG ATGAAATGAT CAACCTGACA ATGAGTACTA

TGCTGCATTG TCCAGAAAGG AACTGTGGAA GATTTTGGGC TGAATTTCAA AACAGAATTT CCTCACTCTC TGGATGTTGG CTTACTTGGC CTTTGATGTT CAGAGGTGGT GCCTTTGTGT TGTTGAACAA TGTTGATTTT GGAGAGAAAA CAGAGTTGAA AAACCCACAA GTCATTCCCT GGGGAGTATT ACCGGAATAC AGAGGATAAT TTCAGCAAGC CAGCAAGGCC TCATCTCTGC TTCTAATAGA TAGGAAGAAA GGAAGAGAGG AACAATACTT TTTTAAGAAG CTCAGCTTTA TCGCCTTATC TCATAGAAAG ATGCCTCCAG TCTGTCTGGC TAAAGGTAAT TGGCATGGGA AAGTCTTTAT CTGTGATTCT AACAAGTGGA ATGTTTCCCT TCATTAAGAG AGCCTTGTCT GGCTTGGGGA AATGAAACAC TTTCTCCGAT ATGAGTGGGC TGTAACCCCT GCTACTAAAT ACTCAGAAGA AATAAGGCGG TTGTGGAGCA GTCAGGAATG AGTCACTTGC CTCCCTGGAA TATTCAGAAA

ACTGAATCAA AAGTACATTC TTCTGGGTTT TCTTAGTCTA ATAGACTAAG GGTCTCTACT TTGTTAAATT TCTGGGAAAC AGCATAGAAT GGGAGAAAAA ACTGGTCACT GTAGTCATGC AAATCTGCAA AACAAACAAA AAAGTCTGGG TATTGCTGCT AACTAGCTAT GTGACCTTAA GCAAGGTATT AACTCTCTCT GAATTTCAGG TTCTTCATCT GTTAAATAGC ATATCTGTAA AATGGGAATT ATTTTCATAT CATAATGCTG TAGCTTTAAA AAATAAAATA AAATGGATGA GATAATCAGA ATTAAAGAGC CTGGGATATA TAGTTAATAT ATAGCAGCAT GTAAAGATCC TGTTAGAAAT GCTAATTTTA CAGTTAACCA TTTGGAGATG ATCCGCCAAA GCTGCTAGTG TAGAGGCAAC TGAGAATTTG CCTGTCCTTC AGAATATGAA TAAATAACTG TCAATGATGT CTCAAGCCTA GAAAAACCTA TCCATCTGGA TGGGTGGGAA ATTTCTAGGC TAGTATTGAG AAGCCCATTT

CTTGGGAAAT AGGTCCTGGA CTGAGTGAAG GAAAAGAAAC AGTAAAACCC ATGGTAAAGC AGCAAGGCTC TCTAGAGGCT CTGGAGAGGA TGAATTGAAT TCTAGAAGAT GAAGTAGGGA AGACGCTTTA CCTTCTTGTG AAATGGATTC AAAGATTCAA AGACCTTCGG GAATCTCCAA TTGTATAAAT GGCACCATAG CTGTATGTTC CATGGAACAC TACTTCCCAG AGATGCCCAG TGAAAAAAGA ATGCCACAGT CAAATAAGTT TGGAAACACT CCATTATGTG GCCACCTCCT TGAAGACTCT AATGCACATT AGCATGTTAA ACAGTCTTGA GAAGTCCTGC AGAGCAGAAA TTGCTTCACA TCTGCTAAGC CGGCAGTTTC CCAATATACT TGATTATGGA TAGTTTTTTC CTTACAACAC CATTCTCTGA TATGCTTCCA ATGACATGAA ATAAATATAT ATGCATGAGG TTCTTCATTA GGGCATACTT TTTAATAGAA AATATTGAGA ATAATCTAAA TATAAATGCA

CAGCATTTAC CTTTTCTGCA TAAACTATAT ACAGGCATAC CTTGGAGATA CTATGGGTTT GGTTCCCACA ATATCTCCAA AACCACATTC GGTTTTATGA CCACTGCCAT AAAACCAGCC ACATGAATTT TTTGGTTTCC CAATGTATAT CAAAGTTACA TTTTTACTAT ACCATAGTCT ATTATATATA CAATAGCATT ATATCTAAAA AACAACGTAA ACACCTTAAT TTAAGGCTGT GGCTGGTTTG ATTTTCTACC CAGACCACTA AAACTTTCTT CATATCAGCA ATAAGGCTGT TTCACTTTCT TACTATTTTT TGTGATAGCA CTTTTCCTTT CCTTCAAGAA TTTTTCCTTT CTATTCACAA TTTGTTTGAT ACAAGAGGAC TAGATTTTAG CTTATCTCAG TTTAAGGTGT TTACATTGTT AGCTAAAAAT GCTAATGATC ATCTGAGACT TCAGCAAGTC ATAATCTTTT GCTGGTGGAA GGTCTTGCCT CAGTGTTGAT GTCTGCTGAC TGGGTGGCTT TGGCAATTTC TTAAAGTAAG

ACAACAATCA AGTTTGACAT ATCAATTGAC CCTTCCTGTC ATAAATGATT TTTTTTTTCT CTGTAGCCTG CAATGCTCTT TGATAGCATT TTACCCACAG TAGAATTTTC AAAATTGGAG TCAATCCTTT CAAACTCTGG TGCTGTTTTA TCAACTAAGT TTATGGAGTA TTAGAAATCC CTTGTTGTCA TTTCAACAAT GTTCACACCA TCTTCCCCAG GAGTATATTC TACCTCAAGA AACCACTTTC TTTGCTCATC TATAAGAAGC AGCTCCTCAT CCACTAAAGT TTTATCCTGA GATTGCAACA ATTCAGTTAC ATCTTCAGGC TCTACTTCTA ATTCTAGTTC TCTTGCTGTT TCTATCTCAT TTGTGCTTAC TTTCTCCGCT GAAGTCTTGA ACCCCTTAAA GTCACTCATG AGGGTTGGAA TCAACTTCTT ACAAACTCCT GTTGATGTTG ATATTTTGAC CTGCTCCCAT GATTCATGGG TATTCTTAAT GGCATCTAGA ATGGTGAACG TTTTCAGAAG GTTTTCAGTT GGCTTTGCCC

GGATCCATCA GACGAATCCC TATCTATGGA AGCTATAGAT TTATAAAATG TATTTCTTTT TTTGTGGGGG CATAGCGTCT CACCCTGTCA CCCAACCTGG AATGCAGTGG CACAGTCATA ACTCACTGAA GACTCAAACT CCTGGGCTCA AGTGATTCTT CCACCTTGGC CTCCCAAAAC ACTGGATTAC AAGCTTGAGC CACTGTGTCT AGCCCAAAAT GTATATCATA ACTAATGAGG CTTGAAAGTC AAAGTGACTC CTTGATCCAT GGGCTACAGA ATGGACGCTG GGTTACCAGA CATGAAAACA ATACTCATCT CCTCATACAT CTCCTTCAGA GCTCCTGGGT GAGCAGGCCC ATTGTCAAAT GAGCAGTAGT ATCTTGAAAG AAATTTTTTT TCTGAGCAGT AGATCTCCAC AGTGGACTTA AAATAGTCAG TAAACTATGC TGTAAACAGA AGTGCTGTCA TCCAAGCTCT GTTTTTCCAC TGATAGGGCA AAAGCAGAGT AGATTTGGCA TAATTCTCTA GGGCCTTAGG ATTTTTGGAA

TGGCAAATTG AGCATTGGCT TCAACTTTTT _TTTTTTTTTτ TTTTTTTGAG ACAGAGTCTT GGTCTGTCAC CCAGGCTGGA GTGCAGTGGT GCAATCTCGG CCCACTGCAA GCTCTGCCTC CTAGGTTCAC ACCATTCTCC TGCCTCTGCC TCCTGAGTAG CTGGGACTAC AGGCACCCGC CACCATGCCC GGCTAATTTT TTGTATTTTA GTACAGACGG GGTTTCGCCA TGTTAGCCAG GATGGTCTCG ATCTCCTGAC CTCGTGATCC ACCCGCCTCG GCCTCCCAAA GTGCTGGGAT TACAGGCGTG AGCCACAGCG CCCAGCCTGT CTTCAACTTA AAGTCGCCAG CTGTGTTAGC CTCTAATAAG AGAGTCTGCC TGTCCTTTCA AGCTTTGAAG CCAGGCATCA TTCTCTTCTC TAGCTATGAA AATCTTAGAT AGCATCTTCT CCCAATAGGA AGCCATTTTT TATGCCCTAA AAATCTGTCG TTTGGTGTAG CCACCTTCAT CATTGATCTT ACCTAGATCC GCTGGATAAC TTACCACAGT

GTCTACATCA TTACTTCTGC TTCACCTTGC ACTTTTATGT TATGGGGATG GCTCCTTTCC TCTAACCTCA TAAACTAACC TCCACTAGCC TCACATTCTT CTTTTACAGC TTCCTCGCCT CTCTCAGAGT TCACAGAATT GAAGAATGTT GGGCCTTGGA TTACACTTTG GTTTAAGGGA ATGCTGTGGC TGGTTTGATT TTCTATCCAG AACACTAAAA CTTTCTTCAT ATCAGCAATA AGACTGTTTC ACTTTCTTAC TATTTTTTGT GATAGCACTT TTCCTTTCCT TCAAGAATTT TTCCTTTCTA TTCACAATTT GACCGTTTGA TATGAGAGGC CTAGATTTTA GCCAATCTCA GTTTACACCA TGCCTTTTTC ACTAAGCTTC ATCATTTTAG CTTTTTATTT AAAGTAAGAT GTGTGACCCT TCCTTTCATT TGAACACTTA CATGATGATG CCTGGCTTCA AAGCTTGAAA GGACAGGCAG ACTCTCTTAT TAGGGGCTAA CACAGCTGGC GACTTTTAAG TTGAAGCCAA TGCTCAATTT

GCCATTAGAA GCCATTGTAG GGTTAATTAA TTTGCCTAAT TTTAATATTA TGGTGTCTCA GGGAATAAGG AGGCCTGAGT AGAGGGAGGG AGATGGGGAA ACAGCCAGTC ATCAGAGCAC ACACAACATT TATCAATTAA GTTTATCACC TTGAGGGCAC AGGTCATGAT ACTTCAAAAC AATTACAATA ATAAAATAAA AAATCATTGA TCGCAGATCA CCATAACAGA TATAATGATA ATGAAAAATT TGAAGTATTG TGAGAATTAC CAAAACGTGA CACACAGACA CAAAGTGAGC ACATGTCATT GGAAAAGTGG TGCTGATAGA CTTACTTCAT GCAGGGTTGC CACAAATACT CAATCTGTAA AAAATTCAAT TATCTACATA GTACCATAAA AACAAGGTAT ACCTGTTTAT A AATCAAGA CCAACAGAAC CCTAGAGAAA ATAGCTCACT CCCTAGCTCG GAGACATTCT AACCAACATA CACTTACCTT TCTTTTTGCT GTGTACAGAA TTCAAATCCC TGTCTCAGCA AAATTGCAAA

GTATCAAATG TCATGTCCAT CTAATACTCA AAACTGCAAA TGTTAAGTCT TGTAAGCCCA GAGACCACTG TATATACAAG TGTTGCTATA AGCATTAGTT CTTCTCCAAA GAAAATAGTC CACTTGGTAG AAACAAACAA AAAGAAAAAA AAAGAAAGAA AAAACATTTT TTACAAGAAG ATTCAGTCTC TTACCTACAT AAGCAAAAAT ATGAGATGTT CTCTTATCAT TTTTCCATCT ATCTTATAAT CTTTGGTGCT GACTTAGACA CTCATTTTCC TTTTTGTACG TGACCATGTA AAAGTTCAAG TCAAGAAAAA CTTGTTTTGA CATTTGTTTT GCTGAGTGAT GGGTCCCTAA AAGAAATTTG GCTTTGCTTT TGAAAAGTTC AGCATGATAT TGTGTGAATT TTTCATGGCT AATGATTTTT AGAACAGTTG TGATGTGTTT AGGTGTTTTA AGAATATGAA GCATTCAGTG GTTTAAGTTG GTTGTTATAA AATGAAAGAA TATGAAGGAA AGCCTTCTTG TCTTAGAACA CACTGATTCA

CAAATAAGCA GCTTCTCTCA AAATGTTGTA ATTACAAAAA TTCCAAGGCA AATATAATAA ACTCCTTGTC GGTGCTATGT CTAGAAACTT AACAGCCCCA AAGAAAGTCC TGACAAGGCA AAAAATATAT ATATATATAC AAATTGTGGA AGCAGGGTGT TGAAAGAAGA ATAAAGACTA TATAAGGACA AACTGTTTAA AAGGGAGGGT ATCCTTGAAA GCTTGACACT TGACTCTTTT GACGAGGCTG AGGGAAAACA CTCAGTTTCA TAGATTGCTG GTACGGATGT AAAATAGTGA CATCCCTATA GAGAGGAATT TGGCAATATC TAGCAAAAGT GCTTATGCAT TTATTCTTTG ACCTAGTAAT CCCGCTTCTA GGATTAGTGG TGAAGATACA CCTCAACAAT AAAAATATAT ATACATTAGG TTATTAGTTA TGGTTTAATT TTTAATAGCA AAATATTTAA AACAACCTAC ATGAACAAAT AGGAGACTTA CTGAATAAAC TATGGTATAT CTGTACAATA AAGTGCAATT CACTTATGTT GTTAATTTGT TCCAAAAATC CAGAGCCAAA GAGTATTTGT TATGCTCTCT TTAGTATAAG AAAGGGGAAA TAAGATATGT GTGCATCTGT TTATTTTTGT GAAAATAAGT ACAGAAAGGA TAAGTAAGAA ACTAGTAAAA CTAGTTATCT CCTAGTGTTA GTAGAAATAG AATGAAAGTG AATTAGGCTT CTTTGAGTAT ATGTTTATAT ATAGTTTTGA CTTTTGAATT ATGTTTATGT TTACATAGTC AAAAATATAA ATTAATCAAC AGAAATAACA AAAAAAGAAG AAATCACAAG CTTTAAAATT TAATACAAAC AGAAATAATT GAATCTAACA GTATATCAAA GTGATAACGT AAACTCAGAA GAAAAAAACA TAATCCAACA TACCAGTGGA ACACAATATT CTAACTGTAT ACATTCAGTG

GTTATAGTCT AAGGACAAGA AAAATTGCAA AAATATCTTG AACTTTAGCT TGTAGGATTT TTATTGGTAG CAATACTAAT GTACTAATTC TGAAATTAAT GTTCGTGTAT TATAGAATTG AGTAAATGAA TAAATATGTT GATGTTATTG GGAACTAAAA TTATCATTCT GGGAGTAGAG AAATATAAAT ATGGACTTGG CAAATGAAAC AAAGACCTGC AGAGAGATAA CCATATAAAC TCATTATTTT AAAAATTATA AGTGTCCTAG CTCTGTTACT GAAAAGGCCT AGATTCAATC TTATCTTGAT AGACAGGAGG GCACCCCTTT CTCAGAACAT GGTTTCCAAA TGCCATTCTC CATTAAAAGG AACAAGGTCT TCTTGGAGAA AAGACTGATT CTAGGTCTGG ATTAGGTAAA GTACAACGTT AGTCTGGAAT TTCTTGCTGA ATCAGAAGTA AGAAAGTGCT CAAAAACATG GGAACATGTC ACAAACACAC GTGAGGCAAC TTGAATCCTC ACTGGCCATA TTTAGGACAA TCGAGCATCA

AAAAAAAAAA AAATGTTGAG AATAATGGAT TCTAACACTT AAAACAAAAA ATAATCCATA GCCCACAGAA GGGGAAGAGA GGGGGAGCTC TTATTTACAG ATGAATATCA AATAGCAAAG ACAGAAGAAA TGACAGAATT AGAGAAACAT CATTTTGCAA AACACCACTG TAATAATCAA TTCAGGCAAG TATTATTAAT GGATGTATTA CTATTGCGTA AAACCAGTTG GGGAACAGGA TATTCATACA GTCTGAAGGT GTCACCCTAA ACATAACTTA TTACAAGTGG AAAATGGTGC CTTTACAATG AAGAAATCTA GCAGAAACCA TCTTAATCTA GTGATCAAAC TTAGTATCAC CAATAATGGA TCATACTGAG TCATGTGTCT CCTAATATGA TGCACCAGGA AGGATGCAAC GTCATGAACG TTGTATTCTT TTGTATTCAA CAGACCACCC AGGGTAAAGG CAGCTTTCTC ACTTACTAAT CAGAATTGTT GGTTTTAATT CATTTTGGAT TTTAAGATTT CTTACTTTCT

TGTCAGCTCA GAAATTTATT TAAGATGATT TTTATCTTTT ATTCAATACT TTAGCTTGGA GAACCATTCA GAGTTTCTAA CTCATTGTAT TGCCAAAAAT AGAAAACAGC ATGGTTTCTT TTGAAAATGT CTAACTTTAA AGTTACTTGT GTGTGTCACT CAGATTCACA TAGCTTTTTT GCCTAGTAAT GTAGTATCAT GTGGCAAGGC TATAAAAATG TTTACAATCT TTTATTTAAT ATGACTCTTG AGAGTTTATT CTAAGGAAAT AATTGAATAG TAACAAAACA CTATTAACAC AAAGCATAGC AATTTGATTT GGGCAACCAA ACACTGGAAA CAACCTAAAT GTCCATTACA GGAATCATTT ATGAAGCAAA CACTAAAATA TTTATTGTGA AGATTATGAG AACATAGAAG ACAGTTATGA GAGTAAATTT GAAAACCTGA ACACAAAACT TACATATACT CCAATTGTAA CTTATAAAAA ATACGTGCAT ATAAGGATAA AACAGTACAA ACAAAAAAAT AGTTGCGTTA GATTGGTAGA

ATTATGGCTC CTTTTGCTGT CTTAATTTTT TCCTTTTACA TTTTGATACA TTATTTTAAT TTTAATTTTA AAATTCAAAA GAATTTGCCA CTCATCTTTG CCACTTCAAG GAAAAAAGAA ATGTGTTCGA TTATTCTGTT CTTAGTATAG TTTTGGCAAT TTCCTCACGT GTAAAAAGAG AATACTATTA ATAATTTCAG TATCTATAAG ACAATATAAA ATTAAAGAAT CTAGCCCAGT AACTGGTACA TGGAACGTAA TTAATAAATC ATTATGGACT TTTTTTCTCA CACCCAAGTA GGGAGGAATC AGTGGTCCCC TAGAGGCCCA GTGTAGAGGT GGCAGCACCA ATCCCTAGGG GAGAAGATCT TGGTGATGAT AATTCCTGAG CAGACAGTTA GCTGAGAATT CAAGAGCAGA AAAGTAAGAA AGAAACAACT TCTTGCTAAC ACCTTTCCAC CCACGTTTCC CTGTTCTGTT GTACTCTGCT TACCCTTTCA TGGATGGAGG CAGAGGAAAG AGAACCAAGT TTGCTCTTAG

TCATTCACTA TGTTGTTTAA TCTGCCTTCC ATCTTTCTTA TCAGTTCAAA TTAGAATGTA GACCTGAATT TAAATCCCCG TTCTGTCAGT TATAATGTGA CCCTAGACAA AACACATTCT CTGAACCTCA GAGAACATTC TTCATTTGTA GAATGGGAAG ATTAATCTAT ATTCCACTTG GATGGCAAGT CTTTTATAAA CTTTATAACC TAAACATGTG TGAGTTGCTA GTATCATTAT GTTGGTAAAG TTATTCTGAG ATATGATAAC AGAACTGTTT TGTCTAACTC CACTAGCATG GTTCAGGTTT AGAGAGTGTG GAATTAAAAG GCTTTATCCT CAAATATGAC TTAAATCCGA TTTTTCTCAT CCACTTTCCT CCACAAACAA ATCCTCAGGA AATGACAAAC TTTACATGGT TAAACATCAG TTTTGTTTAG TCTTTGACAT CCACATGGTT AAATCATACA TTTGAAAACT GCTTATATTT GTGTTGTCTA TGTCTAAATT GAAAAGACTT ATTGAGGAAT AGAAGACTAC ACATTTTTCA

GCAAACACTG CACGTTTTGC AGAATTTCCC CAGGCACCAG TCTCCAGGAA TTTATTGGCT ACTAACAATA CTAAGATATG GATGAATGAG GAAATCAAAA TGGAGATCTT GCAAGTTTTG TGAGAATGGG TGAATGGTCC AAATGAAGAG ATAAGTTGTG AAATATTAGT ACAAGTAAAA ATTATTTACA ATGAAAGACA TTTTGTCAAT AGCTATGAGA ATTTTACCAT TGACCCAGAA ATTCCATTTC TTTCTTCAGA AATACCCACG TAGGTATACA TATAAAAAGT TATTCATTAC AGTATCGTTT TTCATAGGAA AAAGTTTTAA AAATCAGAAG CTATCTAAAC TATGGTATAT CTAGGTCATA GAAATCAAAT GACTAAAAAT GTTAATATAA GCATATGTTT TTAAATTAAC TTGGCTTGGG TCTTCAGCAA AATTGGCTTC TTAACATTGC ACTCCAGAGT TAGACTTACC CACTCAGTCA CTTATCATGC AGGAGCAGAC TCCTAATACC ACATATCATA GAGCAGAGTA GGACACAGGT

TCTCTGCAGG CAGGCAAATC CCAAAGAGAA GGGAGGAAAG GGCTGAGACA CTGCATGGTC AATTTCTTCT GAACTCTGCA ATGTACGGAG GTGGACAGTG TCCACAAAGA TTGCTCCCCT GGACCCACCA TCATAATAAC ACAACGGCTT TGTTTTGTTT TTGTTTTTGT TTTTTGACAC GGAGTTTTGC TCTTGTTGTC CAGGCTGGAG TGCAATGGTG TGATCTCGAC TCACCACAAC CTCCACTTCC TGGGTTCAAG TGATTCTCCT GCCTCAGCCT CCTGAGTGGA TGGGATTACA GGCATGCACC ACCATGCCCA GCTAATTTTG TATTTTTAGT AGAGACGAGG TTTCTCCACG TTGGCCAGGC TGGTCTCAAA CTCTTAACCT CAGGTGATCC ACCCGTCTTG GCCTCCCAAA GTGCTGCGAT TACAGGTGTG AGCCACCGCG CCCAGCCCAC AATGGCCTTT TGTTTACATC TCTAGTGCAG CACTCATTTC ATGTTCTTTC AAGAAGAATA CATATTTCAT CTTTTTATTT TATACAGCAA

TTAGCACAGT GCCTGGCATA AGGAAAATGA TCATTAAAAG CTGGGTGAAA AACCTAATAA AGCTACTGAG GATAGGAACT GCAGACCAGC ATGGAAAGAA AACTATGAGC CAGATATTGA CATCATCCTG AAAGGCAGAA GATTTAGTAT AGGCAAGAAG TATGCTTTTG GAATATAGAA AATCTGGATT ATGATAAGAA AAGAATCATA TTTGTCTTAT CTTACCTACT CACTTCTCAG TTCCACATGT TTCTGAGGCT GTTTGTCCTT ACTTTCTTTT CTGTTTTATC CACTCTTTCT GTTCTTTAGA TTGGATCATT CCTATTGAGC TGACATCAAG TTAACTGACC TTTTATTTTG TCCAAACTGC TGTTAAATGC ATCCAGTGAA TTTTTAACTT TATATAGTAT ATCTTTTAGT CCTAGAATTT CCACATGAGT TTTTTAAGTT TCCATTTCTC TGCTGAGATC TCCTATTTGT TCATTCATTA TGACCATATT TTTCTCTACA TTATTGAGCA TAATTATAAC AGCTCTTCTA

AAATTCTTGT CTGCACATTC TAACACCTGA ATTATTCTGG GGTCAGTCTC TGTTACATTG CCTTATTACA AAAACAGTAT AAGTCACATT GCCTTGTTTC TTAATATGCA AAATGATTTT TGATTGCAGA CTAGACATTT TGAATTAAAC ATTATAGAGA TTCTGGATTC TCGAGAGAGT ATTGACTTGT TTTTTCCATC AGGCAGGTAA CTTGACTGGA CTCAAACTCC AAACTCTAGG TCCTCTGTAA TGGGCAACTG CAGTAATCTT TGTTTAGTTC TTTAAGACTT ATTGGCCAGG CACGGGGGCT CATGCCTGCA ATCCCAGCAC TGTGGGAGGC CAAGGTGGGA GGATCACCTG AGGTCAGGAG TTCGAGACCA GCCTGGCCCA CATGGTGAAA CCCTGCCTCT ACTAAAAATA CAAAAATTAG CCGGGTGTGG TGGTGGGCGC CTGTAGTCCC AGCTACTCAG AAGGCTAAGG CAGAAGAATC ACTTGAACCT GGAAGGCAGA GGTTGCAGTG AGCCGAGATT GTGCCACTAT

ACTCCAGCCT GGGTGACAAA AGCGAGACTC CCTCTCAAAA AAAAATTTAT TGGCACTGCT TGGCATCTGC TATGAATACA TGAAGTTCAT GGGTCAGCTA TAGATCTGGG CACGTTATAC ACAGAATTTG GGTCTCCCTT TCTCTGGATT TCTCCTTTTC TGGATTTCTT TTCTCATTTT CCAGCAGCTG TGGTTGCCCT AAACTCGGTC CTCTGTTTCT TTACGGCAGT AAGATTTGGG AACTTTTAGG TTTTACCTGC CTCTCAGACA AAATAAAAAA TAATTTTCAT CTTGATGCTA CTCCTTTCTT CCAGATGTAG ACACCTCTCT AATTTCCAGT TGCTTTTTAT TGCTCTCCAG AGTCTAAAGA TTATCATTGT TTTCTGTGGG AGAGTTGGTC TGATAAAAAC TACTCCCCCA AAACTGGAAG CTGGAAGCTT GTAATTATGA ATAGACTTTG AGTAGTATTC TTCTTTGGAA AAGGATTTTA ACTACTCCCT ATGTACTTCT TTATTTCCTG TTTTTCTCAT CCGTAATCTT TTTATTTTCA

TACTTCCTAA GTCAGACAAT TTTCCTACTT GAAGATTCAG TGACTGCTAT CAAATGACCC CCATATTACT AAATACAATA TCCCCAACTG CATTTATAAA AAGAAAATTT ACTGTTTATT AGTAAACAAT GTTGTAGAAT AGTAAAATAT TGCTGGGCTT TGGAGCCAGA TAATCAAGGT TAGAATCCCA GATTCTAACT TACTAGCTGG TGTATTAGTC CTTTCTCATG CTGCTAATAA AGACATACCC CAGACTGGGA GACTGGGTAA TTTATGAAGA AAAGAGGTTT AATTGACTCA CAGTTCAGCA TGGCTGGGGA GGCCTTAGGA AACTTACAGT CATGGTGGCA GCAAGGAGAA GTTCCAAGCA AAGAGGGAAA AGCCCCTTAT AAAACCATCT GATCTTATGA GAACTCACTC ACTATCACGA GAACAGCATG AGGGTAACTG CCCTCACGTT TAATTACCTT CCACCAGTTC CCCCCCATGA CACATGGGGA TTATGAAAGC TATAATTCAA GATGAGATTT GGGTGGAGAA ATAGCCAAAC

CATATAATTC CACCCCTGGC CCCTCTCAAA TCTCATGTCC TCACATTTCA AAACTCAATC ATGCCCTCCC AACTGTCCCC CAAGGTCTTA ACTCATTCCA GCATTAAGTC AAAAATCCAA GTTCAAAGTC TCATCTGAGA CAAGGCAAGT CCCTTCTGCC TATGAGCCTA TAAAATCAAA AGCATGTTAG TTACTTCCTA GATACAGTGG GGGTACAGGC GTTGGGTAAA TACACTGATT CCAAATGGGA GAAATTGCCA AAACAAAAGA GTTACAGACC CCATGCAAGT CCAAAACCCA ATAGGGCAGT CATTAACATT AAAGTTCCAA AATGATCTCC TTTGACTTCA TGTCTCACAT CCAGGTCACA CTGATGCAAG AGGTGGGCTT CCAATGGCCT TGGGCAGCTC TGCCCCTGTG GCTTTGCAGG GTATAGCCTG CTTCCTGTTT GCTTTTTCAC AGGCTGACAT TGAGTGTCTG TGGCTTTTCC ATGAGTATGG TGCAAGCTGT TGGTGGATTT ACCATTCTGG GGTCTGGGCC AGGTGCAGTG

GCTCATGCCT GTAATCCCAG CACTTTGGGA GGCTGAGGTG GGGGATCACA AGGTCAGGAG ATCGAGACCA TCCTGGCTAA CACGGTAAAA CCCAGTCTCT GCTTAAAAAA TACAAAAAAT TAGCCAGGCG TGGTGGTGGG TGCCTGTAGT CCCAGATACT TGGGAGGCTG AGGCAGGAGA ATGGCGTGAA CCCAGGAGGT GGAGCTTGCA GCGAGCTGAG ATTGTGCCAC TGCACTCCAG CCTGGGCGAC AGAGCAAGAC TCCATCAAAA AAAAAAACAA AAAAACCATT CTGGGGTCTG GAGAATGGTA GCCCTTACAG CACCACCAGG CAGTGCCCCA GTGGGGACTC TGTGTGGGGG CTCTGACCCC ACATTTCCCT TCTGCACGGC CCTAGTAGAG GTTCTCCATG AGGGTTCTAC CCCTGCAGCA AACTTCTGCC TGGACATCCA GGCATTTCCA TACATCCTCG GAAATCTAAG CCGCGGAGGT TCCCAAACTT CAATTCTTGA CTCCTGTGCA CCCACAGGCT CAATACCACA

TGTAAGCCAC CAATGCTTGG TCAGGGCTTG AACCCTCTGA AGCAATGGCC TGAGCTGTAC GTTGACACCT TTTAGCCTAG ACATCTAGGA CACAGGGCAC CATGACCCGA AGCTTCATAA AGTGGGAGGG CCTTGGGACT AGCTGAGGAA ACCATTTTTC CATCCTAGGC CTCCAGGCCT GTGATGGGAA GGGCAGCCAT GAAGGTGCCT GACATGCCCT GGAGACGTTT TCCCCATTGT CTTGGTAACT AACATTCAGC TCCGTGTGCA GCACCAACTT ACTTATGCAA ATTTCTGTCA CTGGTTTGAA TTTCTCCCCA GAAAACAGGA TTTTTCTTTT CTATTGCATC ATCATGCTGC AAATTTTCAA ACTTTTATGC TATGCTTCCT GTTGAAGACT TTGCGGCTTA GAAATTTCTT CCCCCAGATA CCCAAAATTA TCTCTCTCAA GTTCAAAGTT CCACAGATAT CTAGGGGACA AAATGTTGCC AGTCTCTTTG CATAGCAAGA GTGACCTTTA CTCCAGTTCC CAACAAGTTT CTCATCTCCA

TATGAGACCA TCTCAGCTTG GACTTAGTTG TCCATGTTAC TATCAACATT TTGGTCAAAG CCATTCAACA AGTCTCTATG AAGTTTCAAA CTTCCCCATG TTTTCCTGTC TTCTAATAGC CCTCCAAATT TTTCCAACCT CTGTCTGTTA CCCAGTTCTA AAGTCACTTC TACATTTTTG GGTATCTTTA CAGCAGTGGC ACTCCCCATG GTACTAATTT ACTGTATTAG TCTGTTCTCA TGCTGCTAAT AAAGACTTAC TCGAGACTGG GTAATTTATA AAGAACAGAG GTTCAACTGG CTCACAGTTC AGCATGGCTG GGAGGCCTCA GGAAACTTAC AAACATGGTG GCAGCAAAGA GAAGTTCCAA GCAAAGAGGG AAAAGCCCCT TATAAAACCA TCAGATCTTG TGAGAATTCA CTATCATGAA AATAGCATGA GGGTAACTGC CCCCATGATT AATTTACCTC CCACAGGGTC CCTCCCATGA CAGGTGGGGA TTATGGGAAC TACAATTCAA GATGAGATTT GGGTGGGGAC ACAGCCATAC

CATGCCAGCT AGAGAGCCTT AAGAAAGTCA CCTAATCTCC ACAAATAAAA GGTTTCCTAT TTGTTCAACA AAAATAATGA CACCCCTTTT ATGGGATTTC TGTGAGGACA AATGATAACT AACATAGCCT TGCATAGTGT CTGGCACAAA ATAGCTACTC AAAAAATAAT AGAAACAACA TTTAAAAAAT GTAGACTTTA TTTTTTAGAG TTTTATGTAC AAAGCAAAAT TGAGCAGAAT GTACAGAGAG TTTCCGTATA GCACTCCCTA CCCCCAAGCA CAGATAGCCT CCCCCAGTAT CAGCATCCCG CACCAGAGTG GTACATTTAT TATAACTGAT GAATCTATAT TGACGTGTCA TTTTCATCCA AAATCCATAG TTTATATTAG GGATGCCTCT TGGTGTTGTA CCTTCTATGG GTTTTGACAA ATGTATAATG ACATGTATTC ACCATTACAG TATCATAAAG AATAGTTTCA CTGTCCTAAA AATCTTTGAT CTTCTTCCTA TTCATCACTC CCTCCCCATT AATCCCTGAC AACTACTGCT

AATTTTCCTG TCTCCATTGT TTTGTCTTTT CCTGAATGTC ATATAGTTTA AATATACAGT ATGTAGGATT TTCAAACTGG TTTATTTCAC TTAGTAATAT GCATTTGATG TTCTTCCATA'TCTTTTCAAA GCTTCATAGT TCAATATTTA TAGAATTGAA TAATATTCCA TTGTCTGGAT GTACTACAGT TTATGTATTC ATTCACCTAT CAAAGAACAC CTTGGTTGCT TCCAAGTTTC AACAATCATG AGTAAAGCTG CTATAAACAT CTATGTACAT GTTTTTTTGT GAATTGAACA TTTTCAGCTT TTTTAGCTCC ATTCCTAGGA GTGCAATTGC TGGATTGTAT GATAAGGGTA TGTTTAGTGT TGTAAGAAAC TGCCACGCTC TTCCTAACTG GATGTACTGT TTTGCATTCT CACCAGCAAT GAAAGAGTTC CTGTTGCTCC ACATACTCAC CAGCATTTGG TGTCGTCAAT GTTTTGAGCA ATAGCATTTT GATCTAACTT TTCCTAGGTA TTCTTTTTGA AGGAAATAAT ATGACAGATA

ATAGAGAAAG GATATACGAG GACAGTTCTG TCCTTTATTT ATAGTCCATC ATTTAATGAA GGACTCTGTC CACACTTGGT ATTTTTAACT CTGATCCTCC TCTCCCATGA ACTCTGACAA TCTCCTAAAT CCCTGTTGCT GGCACACATG GTTGTGTATC AGGCCCCCTG TGGTCTGTCT GAAGCATGGC _{τττττττττr} TTTTTTTTTT TTTTTTTGAG ACGGAGTCTC GCTCTGTCGC CCAGGCTGGA GTGCAGTGGC GCGATCTCGG CTCACTGCAA GCTCCGCCTC CCGGGTTCAC GCCATTCTCC TGCCTCAGCC TCCCGAGTAG CTGGGACTAC AGGCGCCCGC CACCACGCCT GGCTAATTTT TTGTATTTTT AGTAGAGGCG GGGTTTCACT GTGTTAGCCA GGATGGTCTC GATCTCCTGA CCTTGTGATC CGCCCGCCTC TGCCTCCCAA AGTGCTGGGA TTACAGGCGT GAGCCACCGC GCCCGGCCTT _{ττττττττττ τττχττττττ} TTTGAGATGG AGTCTGTCAC TCTGTCACCC

AGGCTGGTGC AGTGATGCAA TCTTGGCTCA CTACAACCTC CATCTTTCAG GTTCAAGTGA TTCTGCCACC TCAGCCTCCC AAGTACCTGG GATTACAGGT GCCCGCCACC ACACCCAGCT ATTTTTTTGT ATTTTTAGTA GAGACGTAGT TTCACCATGT TGGCCAGGCT GGTCTCATTC CTGACCTTGA GTGATCCACC TGCCTTGGCC TCCCAAAGTG CTGGGATTAC AGGCATGGGT CATCACATGT GGCCTGAAGC ATGACTGTTG CTTTAATCAT ATGAAATACT GCTCTGTATT GTTATCTATT TGAAATGCCA CACCTCCTGA GCTAAATTGC AAGCTTTTAT GGAGCACAAA CCATATTTAT ATATATTAGC ATGATACCAT GACACATATC AAAAGCTGTT ATATATTGTT ACGTGAATTG ATTCTTTCTC AGTTAAGAGG ACCTCTGTAG TAGCACTTTC ATACCGTTAA TTTTTCATTT TGTGCCCAGC CCCTACTCTG TGAAAAATGA AATGAATCCT GTTATCATTT CCCTCCCAGG CCTTTTCTCC TTGTGGACAA TGTGTGGCTC AAGAGAAAAT TCAGTCAGTA AATTTGTTCA GTGCACAAAC TCTTTATCAC CTCTCACTGT TCTCAAGTGA GATAGAACAG AACATCCATC CAGTGTCTTA CAAATTGTCT GGTATATAGT AGGCACTCAA TAAATGTTTT TTGAATAAAT GCATACATGA ATCCTATTCC TATATATAGT ATGGTAGACA GATCATTGAT ACCCAAAGAT GCCCAAATGC TGATCCCCAG AACTTGTGAA TATGTTACAT TTCATGTCAA AAGGGACTTT GCTAATGTGA TTAAGGATTC AGACCCTTGG ATTGTAAGAT TATCCCGGAT TAACCAGGGC CAATCTAATC ACATGAGACC TTAAAAAAGC AGAAAACATT TCCCAGCTGG GTTAGAGAGA GATGAGACAG AGTAAAAAGG

AAAGAGATTC AGGGCATGAA AATGACTCTA CCCACTGTTG CTGGCTTTGA AGATAGAGGA ACTAGGCCAC AAAACAAGGA GTATGAGTGG CCTTAAGAAA TAGGAAAAAG CCCTCATCTG ACAGCCAGCT AGAAAGCAGT CCTCTGACCA CAAGAAATTG GATTCTGCCA ACCACTCAAA TGAGCAAGGA AATGGATTCT CCCCTAGAAC CTCCAGAAAG GAACACAGCT CTGTAATGCC TTGATTTTAG CCAGGTGAGA CCTGTTTCAG ACTTTTGACC TATGGAAATA TAAGATAATA AAGTTTTATT GTATGCTGCT AAATTTGCGG TAGTTTATTA CTGAAGCAAT GGAAAGCCAA TACAGACAGA ATATACAGAG AGAAAGAGAA TGAGTTCTTT CCTGATAATT TGTAAATATT TGGGTCTTCA CTGGACAAGC TTCACAGAGG ATTCACTGGT TCCCTAGCAA ACCAGCATGT CCAGTCCTGC AGCCTCCCTT TCTTAGGCCC AGCATATGTC AGCTGTGTGC ATAGAAAAAT

CAAAGCAGGA CCCTGAGTAG TTGGAAAGAA AAGATGGTTG GAAATGGGTT GCACTTCAAG TGAGGAAACA AGAGGTAGGA GACCGGCATC TCTTTCTCAT ATGTCCCAGG CTGACTCTTG TGAGTTGTTT TCCCTTGGAG GCTATCGATG ACAGTCACAG TAACCTGATG GAACCTGGAT CATGATGAAA GAAGTAAGTG TCAATGGCTC CGACTTCCAA GGACTCTGAT GTCCCACAGC ACTAGCTAAA CAAAGCCAGT TGGAAATGAG CTTAAATGGG GAATTTCCTG AATATATTCC CTATTGTTAG GAAGCCAGGT TGGCTTCCTT GCCTACAATT ATGCCAAGCA GTCACACTAT AGAGTCCCTA GGGACATGAT ATTAAGTGAT TCTTTTAACA CAAACAACTT AATAATCATT TATACTAATA GCAAAACGGC CAACGGCTGA TATTCCACTT GAAGTAGAAT TGGCTATCCA ACTGGAAGAG AAGACAGGAA GACGTGATCT CCAGGGAGCC ACTAAAAGGA

TTGGCACCTG CCTCTGGATT CCCCTTTTCC TTATATTACC TCTCAGCACT GGCAGGCCTT TATTTCAGGA TACAGTTTCA CAAGTATTAT GTCACGTCTC TGAGAATTAT GTTGGTAGAT ATTTGCTCCT CTGGCCAGAA AGACCTAGTT TGGAGTCTGG AGTCATGAAG GTGACATACA TGTAGCTAGT GACATAAGTG TAGCTAGTAA AAATAGTGAG TAATGGCCCT GAAATTCTAT TGAATGCCCA AAGTGCTGAC CAGGAACAAG CATGCTCTAG CTTATCTCAC AAGGAACTTG ACAATTTTCT TCAAAAATCC TAGTAGCTAA GATTTCTTAG TAACAAAGCC ACTAAGGCAC AATTATGATT AACTTGACCC TTAGGTGACT TTTAAGGACT ATTCTATAAA ATATTACAAC TAATAGTGGA TCCAAGCCAG CACACTCTGC TATATAAGAT TAATTGACAG TGTCCACACT GGTAAAATAA GTTGTTTCAT AAATACATTA GAATTCATTT GCACTTTCTA CACAGCCCCA AGTCCAGAAC

TTTCCCCAGA ATAGGTCTAT GTTTTGCAAT CTGCTACTCC ATACAGAGAT TTGAGTTCAC TTGGCAATTT AGTGCTGCTT ATATGTGACC AGTTAGTCTG TTTTACTTAT CTATGCCTTA AACATTACTA TACTTACTAA CTCCAAGATG CCTGGTCTCA ACTTGACAAA AATACCCCAA GTTGGGAAAT CCTTATGTGA ATATGTAGAT AGTCACAATT GCTGGTTGAT GATGATCTGT CTTTTCCTGT ATTTGAGAAA ATGGAGATAA AATGGACCAA TCCAAATAAT GGATTAAACA TGGGAATAGG TGAGAGAGAG AGAGGAATAC ATGGTGGCTC TCAGTGTCTG GCTTAGGCAG TAAACACTTT CGTTAATAAA GACGGAAAAT AAAAAAGGAA TAATTGGTGT CTAGGGGAAA ATAATGAGCT CAAGTTTTAA CACTCTGAGT TCCCGGATGT GAGACATCCA GGCGCATTTA TCCAAGAGGC AGTTGGAAGC AACGTTCCGG AGCTTAGGAG AGAGGCATGA CCAAAAGCTG GTGGGACTGT

GAAAAGGTAT GGCCATTCTG GAAAACTGTT TGGCAGTTTC TTAGAAAATT AAACATGTAC TAACAACCCA GCAATTGTAC TCTTGAGCAT TTGTCCCAGA TAAATGAAAA AAAAAAAAAG CATTTTTTTT ACACAAAAAC ATATACATGA AAGTTCATAG AAGTGTTATT CATAAAAAAC TGGAAAAAAC TGAGATGTCT TTATTGAGTG AATGCTTAGG CAAACGGTGG TCTATCCATA CAATGGAATT ATGCTTAGCA ATAAAGAGAA AAGAACTATT GATACATGCA ATAACACAGA TGAATCTCAA AGGAATTAAT GCTGAGTGGG AAAAAAAGCA CATCTCAAAA TGGTATATAC TGTACTATTT TATTTACTTA ACATTTTAAA AATAGCAAAA TCATAGAGAT GGAGAACAGA TTAATGGGTA CTGTGTTTTG GGATGGGGAG TGAGAAAAGG GTAAGGTGTA AATATAAAGG GGTAGCACAA AAGAGCCTTG TGGTTGAAGG ATTCTATGTC TTGGTTGTAG TCGTGATTGC AGGAATCTAC

ATGTGATAAA ATTGTATGGG TCTACATACG CATACACACA AGAGCATATA AAACTGGTGA CATGTGAAGA AGCTCCGCAC ATTGTGCCAA CATCAGTATC CTAGTTTCAA TATCAGACTA CAGTTATACA AAACATTGTC ATTGAGGGAA ACTGGGTAAA GGGAACACAG GACATTTGGC ATATATTTTT GCAATTTCCT GTGAATCCGT AATTATTTAA AAATAACAGA TATACTACAT ATCAAAAATT TAATGTCATA AAGTTGATGA GTTTACCTAG TGGATAGCTT TGTTAATATC TGCTATAAGA CTACTGAAAA TGACAGTTAT GCAAGTATAA GCTCAGAGAA CTTTCCTCCC CCTTCGTAAA TGAAATGAGC AAAAGAAATG AAACAGGAAA GGCAAGCAGT ACTGAAAACA GGGAAGGGCT CTTCCCCATA TAACTATATC TGCGACTTCA ACAGCTATTC ATCCAGAAAC ACAGCCTCTT GCGCTAAGAG GAAACTTTGG ATAACAATAT GTTTTCACTC TCCAAGAGAG AAAATGGATA

GATTAATTTT TAAGAAAAAA AAAAAAACCT CACCAATTTC ATGCTGTGGC TTGCACCTTT AATCCCAGCT ACCTACAAGG CTGAGGTGAG AGGCTTACTT GAGCCCAGGA GTTCAAGGCT GCAATGAGCT ATGATTGATT GTGCTATCGC ACTCCAACCT GGAGTACTAA GCTAAGAGCT AAGAACACAG CTGAGAGCGG AGAAGAAACA AACAAATCTG ACCAATAACC CCCACTCCCC TCATTTTACT GGAGTGAGCT GAGACTGCTG GCAAACATGG CCTTTGACCT AGCCTGAACT GTAGCAAAAG TCATCAGATA TTTTTCCACC AATCAACAGA CAGAAGTGGG GAGAAAACAA TCGTAGTTCA TAACTACAAC AAGCAGATAA ACGAAGGCCA TGGTGAGGGA TGGAAGACAT TGTGATATAT CAAAGGCAGG CTCATTTAAA ACTCAACCCA AATTCCAAAC AAAATATATA ATTGAATATG TATTAATGCC AAAGGAGCTT GAGTGAGCTT TAGCACAAAC CCCGCCCTCC

AGCCCCCACC CAAAAAAATC ACTCTGTTCT CTCCCCATTC TTTGATAGGC ATACTTGCTG TTTTCTCACA GCCAAGGTAC AGAGGGGACT TAGAGGAACT AGAACTCTAA TACACTGCTA GCAGGAATGT AAAATGAAGC ATCTACTTCA GAAAACCATT TTATCAGTTT CTAGAAAGTT AAACATAGAC CCACCATGCA GCCCAGCCAC TCTACTCCTA AGTATTTACA CAAGAGAAAT GAAAACGTGT CCCCACACAG TTGTATTTAA AGGTGATGGT TAGCCTTGTG TGTCAACTTG GCTAGGCTAT AATACCCAGT TACTGAATCA AATAGTAATC TAGGTGCATC TGTGAAGGTA TTTTGTAGAT GTGGTTAACA GCTACAATCT GTTGACTTCA AGTAAAGGAG ATTGCTCTTG ATAGTATGGG TGGGCTTCAT CCAATCAATT GAAGGCCTTA AGAGCAAAAA GTAAGGTTTC CCGGAGAGAA AGAAATTCTG CCTCAAGACT GCAGCCTC AA CTCCTGCCTG AGTTTCCAGT CAGCCAGCCA

GCCTAAAGAT TTGCTAGGCA TTATAATCAC ATCAGCTAAT TTCTTAAAAT AAACCTCTTT ATATATATTG ATACAATGAA TGGTTATAGC AGCCTTATTT GTAATAGCCA CAAACTGGAA ACAACCTAAA TGTCCTTCAA TAAGTGAATA CATAAACAAA TTGTGGTATA TCCACAATTT TTACGCAGCA GTAAAAAGGA ATAAATGGTT GAATAAGGAA TAAACACATA ACAAGGATGA ACCTTAAAAC CGTAAGGCTG AATGGAAAAA GTCAGACAAA ACTAATACAT ACTGAATAAT TCCATTTATA TTGAAGTTCT AGAAAATGAG GACTAACCTA TAGTAACAAA AAGCAGAAAA ATTTTGCCCA CTGGTGATGG AGGGGGCGCA GGTATTGTAG AGTATCTGAG AAAGGACAAC TGGATAAAAG GGGGCACAAG AAAACTTTTG AGGGTGATTG ATATGTTCAT TATCTTGTGG CATGGTTTCA TAGGTGCATA CATATGTCAA AACATCAAGT TATACACTTT TAAAATGTTC

AGTTTACTGT ATATCTATTA TACTTCAGTA GAGAGGAAGG AAGAAAGTGG GCAGGGTGGG GGAGAGGAAA GGAAACGAGG GAGGAAAGGC CCTAATAGGA AGGATTTTGG AGTTTAGATT TTAAAATGAT AAAGGATGTT TGACACTCTA GGCATATGAC GAATATAGGA TTATGAGTCC ACAAAAACCA CCAGGAAGTC ATGTATGTTT ATACTTTTAA GTGAAGGATC AGTGGATTAT CAACTCCCTA ATGCTTTGCC TCTCTATGAC TGGCTGCTGT CCTTCTCATC CCAATACTCC TTCCAAAGCC CCTTGCTTAA ATGTAAGCCT TCTTTCCTCC TTTCAACACA TCCTGCATTC CGTGACAAAA TAAGTTTTCC TTAAACAGAA TGTACAGCAT ATTATTTGTA CAATTAAAAA TTTTTGGCCA GGTGTGATGA CTCATGCCTG TAATCCCAGC AATTTGGGAG GCCGAGATGT GTGGATTACC TGAGGTCAGG AGTTCGAGAC CAGCCTGGCC AACATGGTGA AACCCTGTCT

CTACTAAAAA TACAAAAATT AGCTGAGTGT AGTGTGGCAG GTACCTGTAA TCCCAGCTAC TCAGGAAGCT GAGGCAGGAG AATCGCTTGA ACCTGGGAGG TGGAGGTTGC TGTGAGCAGA GATCAGACTA TTGCATTCTA GGCTAGGAGA CAGAGTGAGA CTCGGTCCCC AAAAAAAAAC ACATTTTTTT TTAATGTTTC CTCCTTGCCT GTAGGAAAAA GGCTCTGACT CCTTAGCCTG GGCATCAGAG CTCTATCTAA ATGGACTTTA ACCTGATTTT GTGGCACTAA TTCCATTGCA GTACTTGTCC GCTCACTGGC CTGTGCCTCT CTGCCACTAT TTTTGGAATA ATGTCCTCTC TCCATCTTGT TTACTCAACT ATATCCAACC TCTAAGGCTG TGCTCCTACA AAGCCTCCCC TGGCTACTTC AGCCCACAGA GATATTTAAC TGCTCTGCAG TTCAGGACAT TCTTCTGACT CTTTAAATCA CATTTACTTA TATATGATCT TGTGATATTT TTTGTTGACG TGTTTACTTT AATTTTCTTC

CATAACCTAT TCATTCAACA AACTCAACAA TTATTTATTA AATGCCAAGT TAGAAAAATA TTATTGATTT TATATAGATT ATAGATATGT TTGAAATTTT ATTTGGCAAT CTGCAAGTAG AAAAATAATT ATAATGTGGT ATATCTGTGA TAGAAGTATT AGTGCAGAGA CCATGGGGAA CATAATCCAG CCTGGAAGTT CAGGAGAGAT ACGTGGAAGA AAGGACGTCA GAGCCTTTTT CCTACAGGCA TGGAAGAAAC ATTAAAAAAA ATTTTTTTTT TTGAGATGGA GTCTCACTCT GTCTCCCAGC CTAGACTGTG GTGGTGCGAT CTCTGCTCAC TGCAACCTCT GTCTCCCGGG TTCAAGTGAT TCTCCTGCCT CAGCTTCCCA AGTAGCTGGG ATTACAGGTA CCTGCCACAC ATGGATGATA AATATGATCA TATTTTCTTG TTCTTTTCCT CCTCAGTTGT CTTCCCTGAA GAAAGGAATG CCTTTTATAG ATGACAAACT CCCATTCTCA AGAACAAGGA TTTTTGACCA ATTTAATTTA

ATCAGATGTC TGGCTTTGAC CTAGAAACAC AGTCACGAAA CTTGGTGATT AGAGACCAAT TCCCAAACAT GAGCATTTCT TAGGAAACAC AGTAAAGATC TGAGAGACCC AAGAGCAGAA GGGCGAGAAA CCAAAAGCCA TCAGTTTGCA TAGGAAACAC CTTGTTTAGC CTAATCTTTT TATTTTTATT ACTCTATTAG TCACTACAAC TATTTTCTGA TTGCTATGGT GATAGATGGT TTAAAACAAG CCTTCATTAA GAATTGTCAC ACCATGGTCT CAGTCAAAAA CACCAACATT TTTATTGGTA TTGACAATTA TGGGAATATC CAATTCCAAG AAGACAAGGA GACCTCTGAA CTTTCTAAAT GAAGACTCCA ATCTTCCTGA TCTGATGGGA AGCAGCTTGG CAAGATTACC AACCACCACC ACAGAGAGTG GACTCTAAGC TAAGACTTAA AAGATAAGTA GAAATTATCC AGGTAAAGAT GTGTACAGAG AAGGAAGTAC ATCCAGGGGA AAAGAACAAT ACGTGCAAAA

GTACGGAAAT GGTAAAAAGT AATACTACAT AGTCAAAGCC AAGCAGAGTT CAGAAGGGAT CTGGTGGTGA AAAATACGGC TAGAGAAAGC AGCAAGGATT GGCTTCTAAA ACCTATGTAG TATCTTGGAC CTTACCCTAA ATGTAATGAG AAGCTTCTAA AGAATCTTTC ATTTATTCAT TCATTGAACA AATATTTTGA GGCTTTCTGT GAAGAACATC ATTCTAAGTA GTAAAGATAC AGCAGTGAAT AGGACACATA AAATCCTAGA TCTCACAGAA TTGACATTCC AGAGAGGGAA AGGTAGACAA TAAATACATA AACAAATCAT TTAACAAGAT GATTTCAGAC AATGGTACGT ACTGTGAAAA AAATGAAACA AGGTAATGGA CAGCGAAAAG GCACTGGAAG GAAGCCTGCT TACCTTTGCA TGGTTAGAAA AGATCTCTCT AAGAAAGAGA CCACATGTGA GCTGCGACCT GAAGGATACC GAGAAGCTAG GTGTGCAAAG ATGTGGGGAC AGAACTTTTG

GACTGAATAG CAAATACAAA TGCCCTTGGG TGCAAGCTTT GCCTGTTCAA GGACCAAAAA GAAGGCCAGT GTGCCTGCAG CATACTAAGC ACAGAGGAAA ACACTGTTAT ATGCTGAGAT TGGAATTATA AGTAGAGCCA GATAATATAG TCTCTTATAG GTCATAATAA GGCAACCAGA TTTTATTCCA AGAGGATTTA AAAATCACTG GAGGTTTTGC ACTAGGGTGA GAGGTGTGAT TTGTATTTTT AAAAGATAAT TCTGGAGAAT TAACTATAAT GAGGTAGGAG TAAACTAAGT TAGGGGCTAT TTCAGTGGCT CAGACAAGAG ATAATGGTAG CTTAGACTAG GATAGTAGTC GTAGAAATAA ATAAAAGTGG CACTCTACTT TGGGGGTAGA GTCTATAATA GGTTTGGTTT ATGGATCATA TATGAGAGTA AAAAAAAGAA AATAAATTAA TAATGGTTCC TAGGTTTGTA CCTGAGCAAC TGAATAAATG GGTGCTGTGA ATTGAGATAA AGGAGATTGA GAATCACAGG CTTTGTTTTG

CAAATTAATT TTGAGAGGCT TATTAGACAT CCCAGTGGAG ATTTCAGGTG AGTGGAGCCC ATTGAAAGGT AAGGGACAGG GTCAGGTGTG GTAGGTCAGG CCTGTGATCC CAGGACTTTG GAAGGCCAAG GCAGACAGAT CAGTTGAGCT CAGGAGTTTG AGACCAGCCT GGGCAACATG GGAAAACCCT GTCTCTACAA AATATGCAAA ATATTACCTG GGCATGGTGG CATATGACTG TGGTCCAAGC CACTTGGGGG GCTGAGATGG GAGGATCACT TGAGTACAGG AGGCGGAGGT TGCAGTGAGC CAAGATCTCG CCACTGCAAA CCAGCTTAGG TGACAGAGTG AGAACCTGTC TCAATAAATA AATAAGAAAC GTAAGGGAAA AGGAAATTAA TCTGATCATT GGCAAATGCA TAGTATTTAA AGCCAGGGGA GTAGATGAGA TACTCAAAGT AGGTGAAGAT AAGGAGGCAA TGAAGGCCTA GGACTCTGGT GTACATTTAG ATGGTTATAA GAGGAATAGA

AAGTGGCAAA ATAAGTAACA CTGAGCACCC AATGAGGTGG AGAGGAAAGC CAGGAGATGA AGCATCATAG AAGGCAAGAG AAGAAGGGTG TCAAAGAGGC GAGGCAGTCA TCAACTTCTG GGCAGTCAAA TAATATAAGG ACAGAAAAGT GACCATTGGA TTTGGAAATA TGATGAGCAC TTTGAGTGGA GTGTTGAGAC AGAAGACCAA TTAGAGTAGA TTGAGGAGAT AACGAGAAAT GAGAAAATGT AACCTGCAAG CACAGACAAT TCTTGAGAGA CTTTTCTGTG AAAGGAAACA GACACAGAGT CTTAGCATGT CTTGTCTTTC TATGGGAAAT GTAAATAGTT TGAGATCAGG GATAGTATTT TATTCTGCTT TTTGTACCTC TACATTACCT AGCATAGAGC TAGCTAATGT GCACTTAAGT ATGTTCTCAA TTCTTATCGC CTGAATGACT GGATGGGTGA AAGAATGGAT GGATGGATGG ATGGATGGAT GGAAGGATGG ATGGATGGAT GGAAGACTTC TGATTTGCCA

AGAAGAGGAT ACTGGTAGCA GAAATAAAAA CAGCACTGGA GAAAGAAGAG TTTAGATTTT TATTCTTTGG TGTCAGTTAG ACAGGAAAGT AAGACATTAG AAGAGTCCTT AGATAATTTA TGTAATTGTT CACTTAGGAT TTTTAAATGT GATCACTGAT ATTGGACATG TTCCTAGTGA AGCATTTTTG GTGTTTCACT GGTTGAAGTT AATAACTGTA AAATTATTTC CCGTTCAGGA CAGAAAAACA GAAAACTTGA AGCTCCTATT AGAAAGTTCA AGATTCTCTG GGGTTCTTAG GATTTACTGT TCCCAAAACT CTGTCAAGAA CAAGAAAATG ACCTGTATAC TTAACTGGTC TAGGCAACAG TGGAAAGACA ATTCTCAGAG AAGATTTGTT TTAAGAAGAC ACTTTCCATA GGAATCAAAC AATAGCTTTC AGTGACTAAC ATGGTAAGAC ACAGGGTGTT AGCTCTTTCC TTCCAACCTC ATGGCTGTTG TACCTTACCT TTCGACCCCG TGTTCCTGAA ATTGTTAAAT TCATAAACTT

ACCAAGGACT AACCAGCCTC TGGGGAATTG CTGTATACTT AGCAAACTTA CAATGGACAT ATTTATAAGC CATAATGATA ACTGACTAAT AGGAAATACC CTCAACTGAA AATGAGAGAT CATCATTTGC AAATGAGTTC CCTTGCCCAG GCAACTACTG GGGAAAATGT CATGCAAGCA AAATTAATCT TTGAAATCCT CCTTTTCCAT TTTTTGTGTC TTCCTTTTCC ATAGGCACCA GAAATATCAT GGTGCCTGGA TCTCATCTCT ACAGAAAAAA AAAGTGATTT GATAAACTGA TTTATATTGT GTCCAAATGT GATTGTATTT TCAAAGATAA CCTAAGGGGA GAATGCTGTC TGGCCCAACA GCAGGCTCTC GACTTCATTT CAGACACTGT GGCCAATGGC TGGGAAACAG GTATGAACAG TAGGTTTCTG AGTCCCCTGG AATTATTCCA TTTATGTAGC CACCTCCATG ACAGGAAGCC TCCCTACTCT TACTTCCCAG TTTGTTCATT CATGGCACCA GGTTGCAGAT TAAAATTTGC TCAGTGACCT TTTATCTAAT AATGTGTTAC CTTCTTCTCT TAAAAAGTAC AAGGGACAAA TGCTCATGGT ATACTTTTAG GAGATTGTGG CTCTCTATTA ACAGTATTTA TTCAACAAAC ATTTATTGAG CATTTATATG TGCATCATGC TAGGGACTGG AACCTAGTAA GTGTAGCACA TATTATTTCA TTTAATCCTC ACAACAAACC CATGAGGTTG GTTTTATGAT CCCAATTTTT CAGAAGAAGA AACTGATATT CAGAACCAGT TAACTAACTG GTTCAAGGTC ATGCAATTTC TAAGATACAG AACCAAGAGT CAAAGACATG ATTTTAAACC AAAGCTTTTT CTGCTACTCC ACATTGCTTC CCTAGGTGAG ATCTGAGGCA TTCCGCGAAA AGAGAAGGGT CATAAAGCCA AGGGAAGACA AGCTTAGGAA

AAAAAAGGGA AATGTCCTAA ATAAACAGCT TTCCTATTTA CCAGAAACCA CTAGTTTAAA AATATAATGG GAAAAATCCT ATTCACTTTA ACAATGTTAA AAAAAAAAAA GATAGAAGAA ACATAGGGAT AAACTTAACA CATTTGTAGG ATATGTAAAG AAACTAAAAG ATGTTAATAA TGGCCTAAAG AAAAAAAAAC TTACATGTAT GGGGAGATAG ACCATCTTAC TGGATTCTAA TATTTAATAG TCTAGGTGTT CCATTTCTCA CCAAATTAAT GTATACATTT AATACAATGT CAAACGAAAT ATCTTAGGAA TTGCTTACAA ATTGTCAGAT AATTACAAAG TTTACCTGGG AAATATAAGC ATATATGAAG AGTGAATGGG ACCCCACCAC TCCCCCCAAA ACAAAAAAGG TCTGAAAAGG ACAGAAATCA AGGAGAGTCT TGCCTGCCAG ATACAAAATT CTATTATAAA GGTGTATTGA TGAAAACAAT TTAATACTAG TGTAGCAATA GGCAGCAAAG CAATGAAACA

GCATAAAAAG ACCAGAACTA TACCTAATTA TGATGAAGAT TTAAGGTATG ATAAACATGA CATAATTCAA ATCAGCAGAA ATTGGCATAG ATAGGGTTAA GACAAATAGC TAATCATTAG AGGGGAGGAA GGAAAGGAGG GAGGATAAAA TTAGGTTCCT GCCTTCATCT TACATTAAAA TAAATTCCAG ATGTATTACA TTTAAATTTT TTTAAAAAAA GAAACCACAA AATACTTGAA GAAAATATAA GTTGTTATAT AGTCTTTTGA TGGGAATTTT TTTTTTTTTC AGAGACAGGG TCTTGCTCTG TCACCTAGCC TAGAGTGCAA TGGCATGATC ATGGCTCACT GCAGCCTTGA ACTCCTGGGC TCAAGTGATC CTCCCAGCTC AGCCCCCCAG GTAGCAGGAA CTACAGGCAT GCGACACCCC ATCCAACTTA TTTTTTATTT TTTGTAGAGA CAGGGGTCTT GCTTTGTTTC CCAGGCTTAT CTCGAACTTC TGCCTTCAAG CACCTCAGCC TCCCAAAGAG CTGGGCTGAT GGGACATTTT

TTAACATAGT GCCACATTAC CATAAATGAA AAGCTTGTAA AATACTAATT TTTAAAACTA ATATATATCA GAAATTTTTA TAAACAAAGT TAAAAAGCAA ACACAAAAAA TTTGTAGCAC TTATGACAAA TATATGTATA TATATGAATA CAAAAAGAGC CTTTACAAAA CAGTAAGAAA ACAATGAATA CTCCCAATGG AGTATTCAAA ACTAAACTGC TAAAAGCAAT TCAAAACAAA AAACATAAAC TATGCATATA TGTATGTGAA AAAGTTTAAC CTTATCAAAG AAGTAAACTC TCAAAGAAAT AAACATCAAA TAAGGAAATA GCCTTTTCCC ACAAATAACC AAAATCTGTA AGAATACTGA GCTGCGAATG TTTCAGAAAA AAAAAAAAAT CATACACCTA GTTCGGCATG TAATTAATAT AGATCAGAAC ACTTTAAAAA TATTTATAGG CCAGGCACGG TGGCTCATGC CTATAATCCC AGCACTTTGG GAGGCCAAGG CGGGTGGATC ACCTGAAGTC AGGAGTTTGA GACCATCCTG

ACCAACATGG TGAAACCCTG TCTCTACTAA AAATACAAAA ACTAGCCAGG CATGTTGGCG TATGCTGGTA ATCCTGGCTA CTCGGGAGGC TGAGGCAGGA GAATTGCTTG AACCCAGGAG GTGGAGGTTG CAGTGAGCTG ACATTGTGCC ACTGTACTCC AGCCTGGGCA ACAAGAGCAA AACTCTGTCT CAAAAAATAA TAATAAATAA AAATAAAATA TTTATATACT CTGACCCATC AATTTGTCCA GCATAATTAG GCATGTGTAC AAGGGTTTAC ACACAAGAAT GCCTATTGCA ATATTGCTTT TAATGCTAAA AAAAATTGGG GAAAATGCTT TAAAAATATA GATTAAGACT GTACATTGTG GTACAGTCAT ATAATCAATA GTATACAGCT ATTATTTATT TTCAGCCACT GTCCAAAATA TAGCCTGGCC TAACAACATT CTGTTAGGAT ACGCAAGCAC CGTGAGGAGA TCAGCTATAA AGTATCAGTG TTTCACACCA CTGCTCCTTT GCTAATAACC TTCAATGGCT TTTAAAGAAG

TAAAAAACAA AGGCAAAATT CCTTAGTCAG CCCTTAAGAC TCTCTGTTAC TTAGCTCAAA CTACCCTTTT CAACAACACT GCCCTAACCA GGATGAGTTT TTTGCCCCCC TGGAGTACAT TCAGCCTTTC CTTATCAAAC CTTCCTTTAA ATAAGTATCT TCTCCAGGAC CACTTCACTT TCTTCCCCAA TTTAGCATTT TCTATATCTC CAGGCCTACC TCTATAAAGC CTGTCCTAAC CACTCAAACC CTAGCTTTTT CTCTGAACTG CTAGAAATAT TTTTCTCTCA TTGGCCATTT AGGTAAAAAG GTTTTTACTG TTTATTACCT ACTCAATAAA AATTTTCTTT TTTTGAGACA AGGTCTTACT CTGTCGCCTA GAATGGGGGG AAGTGGTGTG ATCACAACTC ACTGCAGCTT CTACCTCCCA GCTCAACAGT CCTCCCACCT CAGCCTAGTG AGTAGCTGTG ACTACAGGCA TGTGCCACCA TACCCCACTA CTTTTCATTT TTTATTTTTT GTGAGATGGA ATCTCACTAT GTTACCCAGG

CTGGTCTGCT GATCTCAATT GATCCTCCCA CTGTGGCCTC CCAAAATGCT GGGATTACAG GCATGAGCCA CAATATCTGG CCCCAGTAAG CTTTTAAGGC CATTAACATG AGGAACAGTG TTCTTTACAC TATTTTATCA GCTAGGGCTT TGCATGGAGT AGGAGTTTAG TAAATGCGGT TGATGGGTTA ATCAATGTGT GAAAATATTC AGAGCCACCA AAAACAGATA TTATGTCTAT TCTCATCAAC AATCAAAATT GAGTAAACAG CCATTTTCTA ATACAGGAAA CCACAAAACA TTGAATGGTG ACATTAAAAA ATTCCCCCAG CAGGAGCCAA CCAATTTTTT CATCCTGATC CAAGTTAGCA AACTGCAAAA GATAGGAAGC ACTAATGAGT GGAAATTTGA GTAGAAGCAT TTCTTATGAA GGCTGTCTTG ACTGGATCAC ATTTTTATTG CTGTTGGAGG TGCCAAATGT GTGTGTTTAT GCTAATCCTC CACCTCAGGC AACACACAGT CAAGGATCCT ACCAAGTGTT ACCGTCAAGT

GTCTGTTGGC AGCTCAAGGC CCCAGCGTTG TTCCCTTGCA CTAGGGAAAA GACATATTCC AGGTACAAGT ACTCCCACTT TGATGCTACA GAGGAGTTGC TGAACTTTGT GTCATTAATC TCTCTTCGTT AGATCCCAAC CCTGTTTAAA TCCCACTATC TGCCTACTCT GGGTCTTCAC CAATTTACTA GATCATAGTT GGAGAAAATC TACAAAGCCT TGCTCCCTTT AGATTTAAAC AGGTCTCCGT TTAAATTTAG AATTGCTAAC TTCAAGCGGG CCCTTATGCG ACAGTATGCC TGTCAGTCAT ACTACATTTC CTCAATTCCA TTCATGTGAC TGCTCCATAC CCTTCCCTCT CTCTTCATAC TACTATTATC TCTTCCCCCC TCCCTCATTT TTAACTGATG ATCTTGTTTC CTATTTCTCT GAGAAAATAG AAGCCATCAA AAGAGAGTTT CCACAAACTC CTACTGCCTT ATCTAGCCCT GTACCATATA CTTTGCATTT CCTCTCATTA CCATGGATGT ACTGCCTATC TGTGCTTCTA

TCTAAGGCTA ACCCTTCCAC TTCAGTTTTG AATATTATCA GCTCTTACCA ACTCAAGGCC ATTGCTCTAG CAATTCTCTC ATTCTCTCTC ATTTTCTTCC ATCAAGTTTT CCTTTTCTTC AATTAACAGA GTAGCTCCTA AAGGGAAAAA AAAGTCTTCT TTTTCAATGC TCATCATCAC TGGCCATCAG AGAAATGCAA ATCAAAACCA CAATGAGATA TCATCTCACA CCAGTTAGAA TGGCAATCAT TAAAAAGTCA GGAAACAACA GGTGCTGGAG AGGATGTGGA GAAATAGGAA CACTTTTACA CTGTTGGTGG GACTGTAAAC TAGTTCAACC ATTGTGGAAG ACAGTGTGGC GATTCCTCAG GGATCTAGAA TTAGAAATAC CATTTGACCC AGCCATCCCA TTACTGGGTA TATACCCAAA GGATTATAAA CAATGCTGCT ATAAAGACAC ATGCACACGT ATGTTTATTG TGGCACTACT CACAATAGCA AAGACTTGGA ACCAACCCAA ACGTCCAACA ATGATAGACT GGATTAAGAA

AATGTGGCAC ATATACACCA TGGAATACTA TGCAGCCATA AAAAATGATG AGTTCATGTC CTTTGTAGGG ACATGGAGGA AGCTGGAAAC CATCACTCTC AGCAAACTAT CACAAGGACA AAAAACCAAA CACTGCATGT TCTCACTCAT AGGTGGGAAT TGAACAATGA GAACACTTGG ACACAGGAAG GGGAACATCA CCCACTGGGG CCTGTTGTGG GATGAGGGGA GTGGGGAGGG ATAGCATTAG GAGATATACC TAATGTTAAA TGATGAGTTA ATGGGTGCAG CACACCAACA TAGCACATGT ATACATATGT AACAAACCTG CACGTTGTGC ACATGTACCC TAAAACTTAA AGTATAATAA AAAAATATAT ATATATATAT AAAACAACTA AAAATAAATC TTCTTTTTCT GCAGGATCAG TCCATCACCA CACACACAGG CTGTGTTTTA TGTTGTTCCC CAGCTTAAGA GATCGTTCTC CAGATCCCAC TGCTCCTTCC AGTTGTCACC TCAGTTCTCC ACTTCTTTTT GCTGATAAAC

TACTCTAACT AGTTACATAT GATTTCTGTC CCCAGGTCCC CTCCCTCAGT TGTTTTGAAC ATAATCATTT ATATCATTTA TCATTTTCAC TCTAATTGCA CAACCAAAAA CTCCCTTTTT TTTTAGATGG AGTCTCACTC TGTCACCTAG GCTGGAGTGC AGTGGCATGA TCTCGGCTCA CTCCAACCTC CGCCTCACGG GTTCAAGTGA TCCCCCTGCC TTAGCCTCCT GAATAGCTGG GATTATACAC ATGCACCACC ACACCTGGCT AATTGCTTTG TTTTTGTTTG TGTGTGTGTG TGTTTTTTTT TTTTTTTGGA CAGAGTCTCA CTCTGTTGCC CAGGCTAGAC TGCAGTGGCA TGATCTCAGC TCACTGCAAC CTCCACCTCC TGGGTTCAAG CGATTCTCCT GCCTCAGCCT CCCGAGTAGC TGGGACTACA GGCATGCACC ACCATGCCAG GCTAATTTTT TTGTATTTTC AGTAGAGACC AGGTTTCACC ATGTTGGTCA GGCTGGTCTT GAACTCCTGA CCTCAAATGA TCTGCGCACC

TGGACCTCCC AAAGTGCTGG GATTACAGAC TTGAGCTACT GCGCCGGGCT ATTTTGTGTT TTTAGTAAAG ACGGGGTTTC ACCATGTTGT CCAGGCTGGT CTCAAACTCC TGACCTCAAG TGATCCGCTC GCCTCAGGCC CTCAAAGTGC TGGGATTACA GGAGTGAGCC ACCATGCCTG GCCATAAAAC TGCCCTTTGT TAATATGACT GTTGGCCTGC ACATTGTCAA ATCCAGTGGC ATTCATCTTA CTCGGCCAAC CTACGGCATT TGACACTGTC TGTCTTTCCT TCTGTTCCTC TATCTGTTTC CAGTATACTG GCCTGGCTTT CTTTTTACCT CTTTTATATG CTCTTCCAGT CTCAGGCTCC TTTGGGGATT TGAAGGTATG TTGCATTTTG CTATTCAATG AATAATGACA AGTAATGATC ACTTAAGACA TTAAGTGGTC AGTTCCTTTA CTAGGATAAA AATAATTTTC TTCCCAACAT GGGGCATATT CCATTTCCAG TCTGACTGTT CTGTGTAATC TTTGTATTCC TTGGCAGCCC

CTTTTATATC AGTTCATCTA CTGTGCAGGA AATTGGACAA ACATTTGCAC TGGTATAACC AAATACAGTT GAACTTTTGG CTTGACTCTT AGCTGAACTC ACCAAAAATA ATTTCTGTAA GAGACTGAGA CGTCTACGAG TAGGTTTTTC AGAATTAGTA AACATAAATC AAGGATACAC AGGTAGATTT GAATTTCAGA TAAACAACAA ATACTTTTTT AGTATGTCTA CTGAAATATT TGTATCTTAT CTGGCAATTC TACCTGGTAC AGAACTAATC CATTCTCTTG AAAGATCTTG ACTCTGTAAT AAGTTCTTTG GTGATGGAAG GGAGGTATTT CTGTAATTAG AGTCACTGTC TTCCTCCCAG TTTTTTATCC TGGCCCAGAT CTGCAATGAA CACACGACAG AATCCAGGGG GGATGAAGAT GGGTGCTTTG CAGGAAAAAA AAATTAAAAA CATCTGAAAA AGCTTTTGTA CTAAAAGAAT GTGATCTAAA AAAGAAAGCA GGAGAACTTT CTGTCTGCAC TTTACATCAG AACAACCTTG

GCGTCTAGAA GCTGTGCCCT GTGGGAAGTG GTGGTGCTTG GTAAGAGATG CCAGGACCAG TGGTACCCAC TGGGAGCACT GCCAATACCC AGCAAGGAGC ATGGGTGCAC AGTAAGGCAT TGCACTGTGA TTCAGCATAA AATAACAATA AGGGAACGTC ACGGAGAAAA GGCCAGACTT CCTTTGTTTA GAATGTGGGA AATGTCTTCT GAAAAATGGT AGTAAAAAAG CATGCTTGGA TGGTCCACTC CAGGCAAAAC TGACTAATCG GGGGTCAGGG ATACAACCCC TGCATCATAT GTTTGTTTCT GTTGGGCTGA CATGAGGTTC ACTGTGACCA CTGTGGTTTA ACCCCATAGT CTCCTGGAAA TACAGCCAGG TCAAGAGAGC TCCACATAAA ACATAATCAA AAAAATAAAC TCAAGTTTCC ACTGATCAGC TTTTCACAAC TCTTATCCTT TCACTAACTT TGGAGCAAGA TTTGAGAATT GGATGGCTAT TTGAGGGCTA TTTCTGCGCT TTAGTTCAAT GTTTTGTTCT

TTCTTTATTA GAGAACTATG GTTTTTTATT ATATTTACAC TTTAAGTTCT AGGGTACATG TGCACAACGT GCAGATTTGT TACACAGGTA TAAATGTGCC ATGTTGGTTT GCTGCACCCA -TCAACTCGTC ATTTACATTA GGTATTTCTC CTAATGCTAT CCCTCCCCCA GTCCCCCACC CCCCGACAGG CCCTGGTGTG TGATGTTCCC CTTCCTGTGT CCAAGTGTTC TGTTTATGTG ATAGATTACG TTTATTGATT TGTGTATGTT GAACCAGCCT TGCATCACAG TCACTTGCTT ACAAGAAACA AACACTTCAC AGATGGATCA TTATGTGTGA TAAGTGAAAT CCAAGGATTT ATGCTCAGAG GTGGGCTTAA CAGGTAGGAA GAGCAGTATT TTCCTTCAAC CATGAGTGTA TGCAGGTTTT TCTTTTCTTT TTTGAGATGG AGTCTCACTC TTTTACCCAG GCTGGCGCGC AGTGGTGCGA TCTTGGCTCA CTGTAACCTC TGCCACCTGG GTTCAAGCAA TTCTCCTGCC TCAGCCTCCC

AAGTGGCTGG GATTACAGGC ACCTGCCACT GTCTCCGGCT AATTTTTGTC TTTTTAGTAG AGATGGGGTT TCACCATCTT GGCCAGCCTT GTCTTGAACT CCTGACCTCA TGAATCATCC TTCTCAGCCT CCCAAAGTGC TGGGATTACA GGCATGAGCC ACTGCGCCCA GCCCACAGGT TTTTCAAAGA CTAAACTTAA AAAAAAAAAA AAAATTTCCC AATGAAATAT AAAACTAAAG TGCTAAACTG TGATAGACTG TTTTACAAGA ATGCCAGTTT TCACAAGTGT CTATAGAACA TGTAATTTAG ATAGGTAAGA TGAAATTTTG ATAATATTTG ATGGCAAATT TAAACAGGTA TACAACAAAA ATAAAATTCT AAGCCCCTCA ACCAACTGAA TGGACTCCTT CTCTCAGCCA AAGGAATACC AAAGTAAACC TGAAAAACTA GTTTTGGCCA GGATTGGGGG TAGGTGGGGG AAGCCCAACA TGACTCATTA TTCTCTCCTC CCTTTGGAAT TCAGGCACAA CTGAATGTCA GCATTGACAC

TAAAACACAG ATCTTAAGAC TGACAAGCCA GACTCTTTGT AGCAGAGAGC CAGGCCCTGG AAGAAATCAA GTTATTTTAT CCCAAAAAAT ATTTCTTTGA TATATTTTCA AATGGCCCTG CAAAGCTGTC TCTTGTGGGG AAAATTGACA TGCTGTACAG AATTTCCTTC TCTTTCCAAG TTTTTACTGA TCCAGGAGAG ATTTAACTAA GAGGCTAGCA TGTTTTTTTT TTTTTTTTTT TGAGGCGGAG TCTTGCTCTG TTGCCCAGGC TGGAGTGCAG TGGCGTGATC TCAGCTCACT GCAACCTTCG CCTCCCGGGT TCAAGCGATT CTCCTGCCTC AGCTTCCCGA GTAGCTGGGA TTACAGATCC ATGCCACTAT GCCCAGCTAA TTTTTGTATT TTTTGTAGAG ACAGGGTTTC ACCATGTTGG CCAGGCTAGT ATTGAACTCC TGACCTCGTG ATCCGCCCAC CTCGGCCTCC CAAAGTGCTG GCATTACAGG CGTGAGCCAC CGTGCCGAGC ACAAGACATT TACCGTCTAT TCTCTCTGAA

GCTACTATCT AGAGGCTTCA TCAACATAAT AAGACCCTTG GTCTCCACAA CTCCTTATCT TATCCTATTA GTTTCTACTG ATTCCAGGTC TTTAGATAAT AACAACTCTT TCAACCAATT GCCAATCAGA AAGTCTTTGA ATCCACCTAT GACTTAAAAG CCCCACTCCT TCAAGTTATC CCGCCTTTCT GGACTGAACC AATGTACACC TTATATGTGT TGATGGATAT CTGCCTGTAA CTTCCATTCC CCTAAAATGT ATAACATCAA GCTGTAACCC AACCACCTTG GGCACATGTT TTCAGGAACT CATGAGACTG TGTTGCAGAC CTTGGTCACT CATATTTGGC TCACAGTAAA CTTCTTTAAA TATTGTATAG AGTTTGGCTT TTTTCATTGA CACAGGAAAA ATAAAGAATT GGAAGGTCTT TCATCAGTCA CTGAGCCAGC TTCATATCTG ACTGAGGTCA TACAGTTCAG TGATTTGTAG CTTTGCTACT TAGATTGCTA TCCATTATCT AGAAGCATCA GGATCACGTG GGACCTATTG

GAAATGCAGA CTTTCCTCCT AGAACCCAGG ACCTTGGAAT ATTCTTGGCA CATAGTAGGT GCTCAATACA TATTGAACTC CTAGGTGCAA TTCATTAATT CATGAATTAA TGAATTAACA CGCTCTCAAA GTTTAGTGCT TTTTCACAGA CTAGTCTTTC TGCCTCTTAA GCACTCAGCT CACCACGCTT CCAGTCTCAC TCCCCTATTA GTCTGATTAA AATCTGCTTA CATGTGAGTC TGAGATCAAG TGTTATCTCT TCTGAGAAGT CTTCCCTCAC TGGCCCAAAG GAATTTCTCC TCTATTTTAG CACTGTCCCA GTTGACTTGT CATTATTCTA GTCTTTTTCA TATTAGTTGT TTTTCATATA TATGTTATTA AGGAAACTAG TCATTTCCCC TAATAGAACA AAATTGCTGG CCTTTGGGGT TGGCAATGGA GGGGAGGCTC TTCTTGAAAA" GGGGGAAGAG TGTTCTCCTA ATATTTTTCT TACGAGATTT ATGTTGCTCA TCTTTAGCCT TTAGTCCCCC ATTGCCTGCC TACAGTTGGC

AGAGACCATC TGTTCTCTCA CTGTCAGGAA CTGTCTCAAT TCTTGAAGTT CAGAGTCAAA AAAGAAGCAA GTTTTCCTAG CTCTTTGATC AACTTTCAAA GTTTTACTTC CATTTGAAAA TTTACTAAGT CACCAGGAGA TGGTTTATAC TGAGAAATAT CCACTCATAC TCTTCCTCTT CAACTTTCTT CCATATACAC CCTATTACAG GGATATAGTC TTACTCTATA GCTCAAAAGG ATGACCCTAT CAGAAACCTG CACAGTATGT AAAACATTCT CACCAGAGGT TCACTTGTGT ATTTCCACCC TAGAATGGAA GCTCTACAAA AGCACAGAAT GTATCATTTT AACTTTAGAT TCTATTTTCA CACCCAGTGC TTGACACATG ATTTGAAGTT AATATTTATT TATCAAGTGA TTGTTTTAAA ATCATGACTC ACTCAACAAA GTTATAAGAA TAAGAATAGT GTTACAGAAT TGGTATACAC AAGCTGACCA TAATCAACAC ACCTATTATC ATTTTTTTGC GACAGGTTCT CGCTGTCTCA CCCTGGCTGG AGTGGAGTGG CATGACCACG GTTCACTGCA GGTTTGAACT TCCAGGCTCA AGCAATCCTC CCACCTCAGC CTCCCACATA GCTGAGCCCA CAGGTGTGTG CCACCATGTC CAGCTAACTT TTTAATTCTT TGTAGAGACA GGGTCACCCT ATGTTGCCCA AGCTGGTCTT GAACTCCTTG GCTAGAGAGA TCCTCCCTCC AAGGTCCCCC AAAATGCTGG GATCTCAGGC AAGAGCCACC ATGCCTGGCC ATAATCAATA CACTTTTAAG AATGCTAGAA TGTTATATCA GATGCATACT TCAGCACTAT CTCAAGCAAA CTGGGGTGTG GGTTATTCTA CATATAAAGT TCAGCAGTGT TGTTCCACAG TCCCAAACTC CAACTGAGGT CAAATGTAGG GTGCAGCAAG GTCACTGGGG CTGTCATCAA

GGGCCTCTCC TTGCACTCTT GCCAACCCTG TTTCTTGATT GTCTCTACCA CCATGAGTCA CCAGCAATCT CCCACAGTCA CTTGTTTAAA AGTTCACAAG TATTGTGTGA ATTGCAGGCA ACCCCTTGAC TCCCTGATTG CCTGGTCTTC TTCCTTGGGC TCTACCATTT TTTTTCCCCA GCACTCTTTC TGCTGCTCTA AATTTTAATT CATGCAATTC CATATGTGTT TCTCTATCAT TCTTCATCTC TTTCCTCTCC CTTCCATCCA ATTTTGTTTG TCTGTTTGCT TGCTTGCTTG CTTTAATACA TTTCTCTTTT TCTGAGAAGG CTTGAGTCCA AAACTCTCAG TTACCTGTTG TTCTGTTTCC CGTTAGTTAA TCTCCGAACC TTCATAAATT AAATCTGACA AAGTCCCCTG ACTAACAAAG GAAATGCACA AGTCACAGTA AAAGGGGCAC ACACAGAACA CAAATAGACC CAGGGTCTTT TCTGTTCATC ACTCAGCTTT TTATAGGAGA TCCAGGAGAA ATGAAGTGGA AAGGGAAGTG

TGTTGAGTTA CTATACAACA CAAGAGTAAA CTTTCTTATA AGTGGTAATT TTTTTTTACA GGAATAATTG AAAATGGAAA TTACCTTCTC TACTCATAGT AAGTACTCAG TGCGTTCTTG ATGGGATGAG AATGTGTTTG AGCTTTAGTG TAAGGCAGAA TTCTGTTTAG TCTGCCAGTA TTGGAGAAAA ATAAAACACA AAGGGACTGA CATGTAGGAA GTGGCACCTG GGAGGGTCTC AATTCTTCCT ATTACAAAAA TGCCCCAGAG AAATAAAAAG CTTGTGTACA TGTTGAGATG GGAGAGTTCT CTGGCCCCCC TCGCAGGATG TGTGACAGTG GGGTGGCTCT CTGCTGCGCC ACCATGAGCT CAAACCCCTC ATAGGAGGGG GAGCACACAG GCAGGAAGGT GCAGGAGCTG GGCGAGCTCT TTGGGCTCTG GCCCCGTGGT ACTGTCTAGA GGTGGGTGCC TGCAACTCCT GAAAGCCCAA GTGGGCATGT GTTACAGTGC ACTCTTTCAG CTTTGCTGTC TGCAGCTTAA

GCGTTAACCA GCTCAGTTTC TTCTTGGTAC CCAGGTCCTT GTCTGGCATC CAGGAAGAAT CAGGTTACAC ATGGACTTGA AGGATGAATG TGGGAGTTTT ATGGAGTGGT GGAGGTGGCT CTCAGTGGGA TGGATGGGGA GCTGGAAGGG GGATGGAGTG GGAAGATGAT ATTCTCCTGG AGTTTGGCTG TCCAGCAGCC GATCTCCTCT CCAGTCGTCC CCAGCCTCTC GACGTTCAGA TGCTCCTCTT CTCTCCTTCT CTGCCATGCT GTTCTGCCGT TCATCTGCCT GTCTCTCTCT GGAGCCTGGA ATTTGGGGTT TATATGGTAC ACAATAAGGG GCATGGCAGG CCAAAAGGGA ACTTTTTAGG TGCAAAAAAC AGGAATGCCT CTTCTCACTT AGGGCTATAG ATTTTCAGGC TTGAAGGTGG GGCCTTTACC AGCGAACCTG TATTTCCCTG TCTCCTGTGC ATATCAATGT AATCAAATAC TGGGCTGATC CAGGATGTTT CTTTAGACCA ATTATGGGTA AAATAATTTA CATTCAGGTT

TTTATATTTG CTTTTGTCAT TTCTTTTTAA GCAATCATGT AAAATATCTA TACGACAGTA ATAGATGATA GCGAACCTAA TTAAAATTAC CAGAAACTTA AGAATCTCTA ATGATTTCAA CTGTAACTAA GGTTATTTCT CTTTATGTTG AACAATGTTG GGAGATAAGA CACAAGAGTT TCTGAAGTAT TTCAGAAACA CAAAGAGGGA GGTTATATAA ATAATATTTT TTTCCTACTT TGGGAAAATG AAAGCTAGTC ACAAAGTTAA ACGAGTGGTT ATTTTAATAT TTAAAATACA GGCTTGGATG TATTTCCTGT TAAAGAAAAT AAAATGCAGA ATATTCAAAA CGTCTGACCA CCCTTCTAAG AAAATGCATC TCTGAGGTAT TTTTCCTTAG AAGTTATTGT AAAAATCCTG GAGAAGCTTG AACACAGCAA AGCAAACAGG ATGCAGAGTT TAATCTGTGG AAAGCTTAGG GAAGAAAAGC AAATCATTAA AAATAGGTCT TCCTCTGAAG ATTTTTAAAA CGCAAAGAGG GTGGAATAGC

AATGATAATA AAAAAGCTGG CATAGAGAGT GGCACAATTT GCTGTGCCAC TGAGCTGACT GGATGTGTTC TGAATTTCTA GGCATTAGTG TACCTTTCCA CACGCATTCT CCCTTTAAAA AAAATGCCCA CACACTGAAT ACTTTTTTCA TGCAATTTAA AATAAGCGCA CCATCTAGTT TACAGAAATT CACTAGAAGT TATTTATCCT AAAATAGCAG AGATCTAGAA GAATTTTGAG CTCTAGGACA TTTTAGACAC ACAGAAAGAA GAATCTGGAC AAGTCTTGAC CAGACATGAC AGAATAGAAA TTTCTTTTCC TATTTATCTC TTTGAATAAA ATTTTCAGGA TCTTACAGTG GACAAGTTTG TTATCTACAC ATTGTGAAGC ACATTGATTT CTCCTCTGTA GCCTTAGGAA GATCTGAGAG GTGACTGAGC TGATTGAATG ATCCGTGACC GCTCTACTGG GACCAGTAGT AGAACTTTAC TGGTGGAGAC CTGCTGGAGG TTTGAGAGCA GACTTTGAAA ATTACTAGAG CTACACAGAT

ACTGTGTGGC TAACTGGATT ATGTTTAGAG GCTTTCAGAA C ATGCTGCT GCTGCTGCAG TGTAGCCAGG ACGCACAGAG AACATCTAAG GCTCTTGAAT GGGGCGATAG GGACAGATTT CAGCAGCCAT CTGACTTCAG TGCTCATTTT GATGCTTTCC CTGCAGGGTG CAGTGTGCAG TGTGCAGTGT GCAGTGGTGG GAGGCTCACA CAGGAATACT TGCTTCTGTA GCCCTAATTT CCGGTTCAAA CTCTGCATTC ACCTTGACAG ATTCTTTCCT TGGCCAAAAT TTAGTTAGGC TTCTGGGCTT TCTCTTATGC CCACCTGCAG ACTTTTTGGT AAAATCCAGT TTTAGTAAAG AGCTCTGCTA AGTCAGTTTA GCAAGAATCC CCACCTCAAA AGTCACTATC TCCCTCCCTG GTAGTGTCTG GCTTGTCTTC AGCGAGAATT CTATTAGGTT CTGTTAGATT AGAATCCTCC TTACCCTTGA TGCTTCCTCT TAGTATTTTT TCATCCACTG ACTCCTTGAC CCACCTTGCT CCTCGGCTAT

AAATTCCCAC TTGCCCATAC TCTGCAGTTA AGACTATTTT CTCCCCACTA CTGCAAAATC CCATTGCCAT GGTCCCTATA CTATCTCAAT GGTAATGAAT AAAGTCTGCC TTACCATGCT TTAACAAGTA ACATTGAACC ATTTTTTTCT TTAACAATCT GCTGCACAAT GAGATTACTA AAACTTTATT CCATTTTGCC ATGCTGGATG TCCTCAATGG AATGGCTCTT GTGAGCACCA AATCATTGTG AGAAGGAAAA CCCATCTCTT ACAGCCCCCT GTAACGTGAT GTATGTTACA TGTGATGTAT GTTACATAGT TTTTTTTCAT GTTGATCACT TTTTGCCCAT TTTCCTATAT CTTATCAGTT GGAAGACTGT GGAAGTTTGT AGTACTAAGC CACAAGATGA CTAAGAAGAG TTGAAAGGGC AAGTGGGGCT - AAAAACAGAT TTTGTTTGAC TTACCCCACC ATTCCCCCTA TCATGGGGCT GAATCTGCCT GGAGGAAGGA GCATCTTTAT CTTTGTACTG TGAACCACAC AGTCTAGCAG

CAGCACAGCC AAGGCACTTG GGGTTTCATG AGACTAAGTA CATGCAATTC TATTGTAAAG GCTTAAAATA TATACAACTG ACCCTTGAAC AACATGAATT TGAATTGCAT GGTCAGTTAT ACGCAGATTT TCTTCCACCT CTGCCACCCC TGAGACAGTA AGATCAATCA ATCCTCTTCC TCCTACTCCT CAGTCTACTC AAAGATACTT GAAGTCTACT TGAAGATGAC AAGCACAAAG ACATTTATGA TGATCCACTT CCACTTAGTG AATAGTAAAT ATGTTTTCTC TTCCTCCTAA TTTTTTAACA CTTTCTTCTC TCTAGCTTAA TTTATTGTTA AGAATACAAT CTATAATACA TATGACATAC AAAATATGTC TTAGTTGACT GTTTATGTTA TCTGTAAGGC TTCAGGTCAA GAGTATGCTA TTAGTGGTTA AGTTTTCGAG GAGTCAAAAG GTGTATGTGG ACTTTCAACT GCAGGGGGGT GGGCACCCCT GCCCCCATGT TGTTCAAGGG TCAACTTTAC TGCCAAAGGC AAGCCTTTAC

ATCCACTTTT TCCATCCCAT CAGTAAATGG AAAAAGATAG CTACAGTATC CCTGCGTCAA ATCTTTTTTT TTGCAGATCA CAAATTGGCC ACTCACCTTG CTCTGTGAGG GGTAAAATGC CCCACTTTCT TTAGTAATAT TTAAGTTAGA TAATATTTAA GTTATAAAGT TGTTCTTTGT AATCGTTAAT TGTAATTTTT ACATAGTTTC TTTCAAACAG AAATAGCATT TTTGTTAGAT AACCTCCCGT ATAGATGATG AAACTCCTTT TAAGGGCTAT CTGAATTTTA ATTCCTTGAA AAGGCAGAAA TTGGATAGCT AGTAGTCATA AATGTACTGT GGCTTCCCCC AACCATCTGG GCTATATAGA AGCTGCATCC TTGGACTGCA GTAGAGGAGT CTTACAAAGC ACAGAGCAAC TTCTCTCCTG GGTTGCGCTA GTTATGATGG CAATTTTAAA TGTGTACTTT TACCCAAAGA AAATCCTTAT TATCAACAAT CACAATGCCA TCATAACCAT GGTATAAAAA ATTCAAAATG TCCCAGCTGA

AGTGGAGGCA AAGACTCAAG TTCATGGAGT CAGAGTTTCC TTGCTATTCC TCTTTTTCAA ATGACCATTT AGTAAGCACC TGAAGAAAAT ACTATGGACG GCATTGAAAA GTGAAGATAG GTTTAATCTT CTCGAAAATC TAATTCTCCA GATGAAACGC TGACACTTAT CCACCCCACA GACCCTATAG CAGATGTGTC ACTGGCCATC ACATTTGACA CAGAGAAGTC ATAACTCAGT CAGCACAGAG ACATTTCCAT GAGTTTCTGA ACCATGGACA GAACGTCGTC TGTGGGACAT GAAAACTGGA ACTTAGAGGA CAGGCACATC TGAGAAATGG GCAGTTTAAA GGCAGAACAT AGCACATATG TGACTGGGTT TTAGAAGCAA ATTTACAAGA CGCACTCTTC TTCATCCTAA ATAATCTGCA ACCAAAGCTT CCAAAAAAGA CAATTTAGGA ATGCAGAGGT GAGGAGTAGG GAGGGGAATG GGATGAGAGA GAGTGGAGAT TAATGGTGGG CAGAGCGAGG TTTAGAACTT

AGTGGTTTCT TCAGGTTCTG AACTGAAATT TGTATACTGT AAAGGCACAA ACACCATTTT TAACAAAAGT GAGCAGGACT TCCTATCTGG TTCAGAAAAT AGGTGAATAA ATAGTACGAA TTATTAAAAA TAATAATTTC CACTTATACA TAGGAAACTT GATAGGAACC ATGATAAATG CTTAACTCTT AATCTTCAAG GAACTCTGCT AGGGATATAA TATTATAAAT CTTGTTTTGC AGATGGAGAA ATTGAATTTT AACCCAAGTT ATCATAACCC TTAAATGATT AAATGATACT GTTACATGAG AAAGCTGCGT ATCTGTTTCC TGGATTTGTA GCCATAATTT GTGTCTCAAG TCCCTTTTGC TGCCAGCTAT CTTGGGTAGG TGTGTTCCCT TTGGGCTGTT TGATACCCCC ACATTTATCT TTTTTTTTTC TCTTTTTTTG TTGAGAGAGT CTTTCCCTGT TGCCTAGGCT GGAGGGCAAT GGCGCGATCT CGGCTCACTG CAACCTCCGC CTCCTGGGTT CAAGTGCTTC TCACGATTCT

CTTGTCCCAG CCTCTCTAAT AGCTCGGATT ACTGGCATGC ACCACCACGC CCACCTAATT TTGTATTTTT AGTAGACAAG GGGTTTCTCC ATGTTGGTCA GGGTGGTCTC AAACTCCTGA CCTCAGGTGA TCTGCCTGCC TTGGCCTCCC AAAGTGCTGG GATTACAGGT GTGAGCCACC ATGCCTGGCC CCAAATTTAT CTTTAATGCC CCAAATTATC TAGTTCCCAT GACTGGGCTT CTGCTTTGAT CCTTTCTGCA CTTGCTGGAC CCTCTCCCTG GGAAATGAGA TTGTGTCCTG AGCCCCTAGT TAGAGGCTAT GTCTCTGCTG TTCCTGAATG GGCCTCCTGG ATGAGACCTC ATTAAAAGTC TAATTCTCTT GGAGAATTGA GAGATACCTA TTTGTCTCAA AATCATTGAA ACCAATTAAT GTATTATGAG CCTCTATCCA GTGATTTGTA CCTCAATTCC CCAATCCAGC TGTCAAGGCC AATTTGTTCT ACCTTACCTA GTAGGTAAGT CTGGAATTGT AGCTGTGGCA TTTTCAGTAA

TGGTACTCTA GGTTAGCAGT CCCCAACCTT TTTGGCACCA GGGACCAGTT TTGTGGAAGA CAATTTTTCC ATGAAGGGCT GGGCAGGGGA GTGGTTTCAG GATGAAACTG TTCCACCTCA GATCATCAGG CATTAGATTC TCACAAGGAG TGCGCAAGCT AGATCCCTCA CACATGCAGT TCACAATAGG GTGTGCACTC CCATGAGAAT CTAACACCGC TGCTGATCTG ACAGGAGACA GAGCTCAGGC AGTAATACTC ATTTGCCTAC CGCTCACCTC CTGCCGTGCA GCTCAGTTCC TAACAGGCCA CGGACCAGTA CTGGTCCACG GCGCAGGCAT CAGGGACCCC TGTTGCTAGG TATAAGCATC TGGCTGCTGC ATGTCTTCTG TGTAGCTACA TCTGTATGTG TATCTGATGA GATATAAATT ATTTGATTAT AAATTACTTT CTTCATATTA GAGTTGTGAA TGAGTATCAC ATATAATTAT ACATAAACTA GGAATATGCT TTTTAATAAT GTATATAAGT AAGTTTCCTT AACTATGACT

TTCATCTTAG CGTAGTAAGA GGGTGCTAAG AAATATTTGT GATGAAAATA GGCATTGGTA GAGTTGAGAC CACTGGGTGA TGAAAGAGTG TAAAGATTTT AAAGCCTTCA GATGCTGGTT CAAGGTGAGA AATGTGATTG GGAGCAAATC AATTAACTTC TTGAAGTCTT ATAGGGCAGT TATGAATACT TAATGTTAAC ATATGTAAAG CTCTTCTGCC CTGTATACAG TAAATGCTAG TTAGCTATTA TGATCACTAC TAAAATGGGG ATGACATAAA CCTCATAAGG TTTTAAGTAT TATGCAAGAT ACTATACAAA GTCCAGTAAA TATCACATTC AATTGAATCC ATGATGTCCG ATTATTTTAG CTACTTCCAA GAGAGAAAAA AATGCTGTCA GTTTTACTGT TCTTATAGAG AGCAAGGCAG ATCCCAATTC CCAATGTGGT AACGTGAAAA TTTTTGCATT TGAATCAACA AAACACTTTC TCCTTTCTTT CCTACTATTT AACAACTGGT AAGTCTATAC TCCCCCAAAT CTGGAATTCT

CCTTTCTTAT TCTTTTTCCT CCTACCAAGA CCGCAGGATC TTTTACTTGG CTATAAGGGG TAAACCTCAA GTAGTACAAG TTCTCTGTAT TACTTTTATA CTCTGTCACA GATTCCCTTT GTTTCCTCAT CTCCATGTGA ATTTAGTTAA ATTCTCAGCA TTCTGATCCT TACTATACAA GGTAAATGAA TATAAAAACA AAACGAAACA AAAACCTCTT CCTATTTACA TAAGGCCCCA ACCTAATATT TAGTGATATA TATTAATGTG AACAAGGAAC TAACGAAGAC TGGGAAGAAA TTCACAGACT TGAGAGAAGA AATGGCAGGA TTTCCTGGGA AC AATTTCAT GTAACGTC AA AGGTGGTAAA AGGTCAAATA GAATGAAGAT GGAGAATACC GGATTTTCTT ACAAAATGAT TTCCCAGGAG ATCTCATCAA ATGCACGAGG ATACCTTCTC AGTTTCACCT AGTGAGTAAA AGACTGGTAA CATAGCTCAC TTACAATTTG GATAAACAAA ACTAAACAAA CAACATCAAA ATTTCAGAAA

AAATAATAGC AAAACAGAAA TCAAACACTC AAATTTTTGG TCCTTCTGTT TATTTCATTT TGGATACTCA GTGAATGTTA ATTAACCAGG AAACTTAAAA GTTATTTCAA TTATGAACCT CTTCAATCCT TCATCAATTA TTTTGAGTAT TCTGGTCTTA AAAACATCTC TTTCTTCTAC AAACTTCTGA AAGAGATGAA CACCTCCACC TACACCAAAA TAATGTGCTT TGCTGGCCAA AAGTACACGT CCATTTTTAC TTAACAGTCT AAGGAAAGTC TGGTGCAAAT TACTATAATA ATCTGGGTTG TAAATGGTTT CTGAGGTGAG AATGAGATCA TATTTTACAA AAAGTTTTTC ACTACTTAGT ACAAGCTTAC AAAACTCAGA CCACTCACCA GAAAAAAATC GGCATTTATA TAGTTGTGTT ACTTTTGGTT TCCTGCATCT TTTCACATCT GGCTCATTTA CATCATTTTC TTCATCTTCC AAAGTGGAGT TAGCTACTAC ATTAGGTAAG GTTACTTCAT CAATCACCAT ACTGTTATAA

TCTTGAAAGT GAATTTCTTT GGACCCTCCC TTGAATGCAG TTATACCTAG TAAACCTGAT CCACAACCAA GATCCAAGAC TTTTTTCCCA GCAAATTTCA CTTTGGCCTT TGTGAAATAA GCCAGGAGGT CAAAGGTACA TTCCCAGATT TTTAAGCCTC CCTCATAAAC ACCTGTAATC AGATCAGAGT GAGAAGAAAA GCTTTTTGAA ACTATGTTTT CTCCAGGGAA GTTCTCTTTC AACAAGATGG TTTTCACTAC TGATAACTTA ACATGCTGGA AACCTGGTAA TGTTTCTATG ACTTTATTTT CTAACATCTT CTTTAAATCT TTAGGCATAG CATGCTCTTT GGCAGCTCTC AAGGAGGGCT GTTTTCCATG TGGCTCCAAG TTCCTTGAAC TGCTGGCTGC ACTGAGTGGA CTGTCTGTGT CTTGAGAGGG AGCTGCATTT TCCATTGACT TATGTTCCCA CAAGTGATCC TGAGGCAAGT CAAATTGTTC TGCAGAACAT TTTCTGTCCC TCTCTTCTCC TTTTTGACTT TCTGAGACTG

ACAGCTCTTT TGAGGAATCC AGGGTCAAAG CTCCATCTCT AATGGGTGTT AATTCATTTT CCAGATGGTC TTCTATAGTG AAATTAAACT GAAAGGTCAT CCTCTTATTA AATGCACACA ATCTTTAAAT TCAGATTCTT CAACTTCTGG ATAGAATTTG ATGATACACA CAAATCTGCC TCAATTATTC AATTAGTTTT GTTGGGCCCA ATTTCTCTTT AGCAGCTTAT ACATGGTAAC AAATATTTAG AGATATTTCC AAATGACTTT TTAGACGTCT TTGGTCCTCT TTCCAAGCAG CTCTGGAAAG AAAAAAAAAA AAAAAAGAAA GAAAATGATG ATTAAAGCAA AATGGCACAT TTCACTAAAG TGTAATATTA AACAGCCACC CCCACCCCTC CCTGTCCCAC CATACAGCTG CTTTTTCTTA AAAAGTTGTG GGGAAGAGAG AGAGATAAGA GATTTGGACA CTCATACACA CCTTAAGGGT TCCAAAGTGG GAGAAGAAAA TCAACTATAA AAACAAACAG AAGAACAACA

GCAACCACCA CCACTACCAC CTGGACAAAC ATAAAGTCCA AGATATTCAG ACAGGACAGC CTAGCTACTT GCTGTCTTTC AGCTGTCTTG ATTTGTGTCC AACCATATTC ACCCCCTAAG CTTCCAGAAT AACTTCACTT CTGTCTTTTA CAGAAGAGGT GCAGTATTTT ATTTTGGTAA GTCAGCGTCC CTTTAAAAAC ATGCATAGGT ATGGCCTGGT GTGTGTAAAT TCATCCAAGA CTTCACTCCA AACATTTAGT CGAGAACAGC AGCCCTAAGT GTATAGAAGT GGGGGTAATT TGGCAATAAT TAGTAAAGAC TAATTCGGTG GCAGAGCAAA CGCAAACTAG GGCAGTGCAG TAGTTTGGAG AGACCTGTAG AAATAAGAAG CAACTTTATT GAGAATCTTC TATCTACTGC GCTAGACACT ATACCATCTG CCTCAATTTT CACAGTTCTG GCAAGTGGGA TCTTTGTTCC CTTTATACAA GATTTACAAT TTGGGGGAGA GGCGGGTCAC CCAGTCCCGC GGCTAGGAAC GCGCCTCTTT CCTCTCCCAT CACGCTGCAA GGCTTGGAGT CACTTCCGGC TGCAGGTCCC GGAACAAATC CGACCCCAGA AGTGGGGACT TCTGGCCCTC ACCTCCCCAT TTGAATGTAA TGTTTACAGT GATCCAGACC TGGGGATGCT TGCTTCCCGA CGTGTCCTGG GATCGCGCTT CTGAAAAAGC TCACCTCACA ACGCCTCCTC CGGACCTAAA TCGCGCACCA GTGAGTCGAG TCCTCCAGGG GCTAGAGAAG CCCGACTTTC TTTCCGGCCT TGAGGGACCC GGGCTCACCA AGAAACCAGC CGCCCTCCTC TCTATGGTTT TGGAGCCGGC GGAGAGCGCG CAAGGGTTGG CGGGACTGCG AGTTTCCGGT CTGGGCTTTG GCGGGTCTGG TTTGAAGCTC TCCTGTTTGA CGAAAGTATG TCTCAGGAAG GTGCGGTCCC

AGCTAGCGCG GTTCCCCTGG AAGAATTAAG TAGCTGGCCA GAGGAGCTAT GCCGCCGGGA ACTGCCGTCC GTCCTGCCCC GACTCCTCAT ATCCTTCCTT GGTTGTCACT TCTACCTAGA GAAGGGTGTG GGCGGGTCGC GAACCTTTCT CTTCTGTCCC TTCAGACCCA CCGCCAGGCT GGGTTATATT ACCGCGGCCT GAACCCCCTC TTTTCTTTGT CAGTGAGTGG GATGAAAAGT GAGGGACTGG AGGGGAAGCG ACAACCGTGG TAGATTTAAG TAAGGCTTTG GCCCTGGAAA GCCTCGCGGA CGTGTTCTGA CCCAAGGTTT TAGCAGTGGA TGTGGCGTTT TCTTCCATTC CTTCTTTCAG TTTTTCTGTA CTCGTTGCTT GCAATTAAGT GTAAATACTT TTGCTAGTGG ATAATGGGGG AGGCAAGGAC TGAGACCTGC GGTATGACGA TAGCTCTGGC TCTTAATAGT TTGAGGTAAA GCGAGATACT CTGAGCTTTT GTCTCCCGTA AAAAGGGTGG TGAATATGAA

TAAGGGCTTT CTTAGCGTTA TAAGAATTAA AGGGCATAGT TCTGTGGTGT GAAATCTTTA AAAGATGTTC AGTAAATAAA AATGATTTTC CTCCTTCCCC TCTCAGACCT CTTTTTCTTC TTTGTTTCTT TTTTTTTGAC AAGTTCTCAC TCCTCTCACC CAGGCTGGAG TCTTTCTGAA AGAGTTCTTC CGCTTGTTGT TGGCTTTCAA CTGTTGGATT TGAGGCGCTT AGCGCCTTCT TCGTCCGGGT GCAGCACATT CTTGATTGGT CTCATGCCTT TGTGGTTGTA AATGTGCCTG GAATCCTAGC CTTTCATGGT AAACCATATG TATATGTATC TTTTTCACAA CATTTGAGCC CAGCTTTATA CAATTACACT CAAAAGAAAA AAAGTAACCT TCACTTGAGA GAATCTCAAT ACTGCACAAA TATTGTGCAG CTAAAGCCCT ATGTAATCAC ATAGAAGTCA TTCACCTAGG CATTAGCAAA ATCTCAGAAG GTGCCAAAGC CCCCTTTTTT AGTTTTTGTG TAGGTACAGA ACTGCCGTCT

TCAAGGAGTT TCAACTTGAA AACAAATAGC CACCCTCAAA ACATTCAAAA ACACTTAAAC TGCGTGCATA ATGTGTGTGA GACATGGTGT TAGGCTTTGG GAGAACAGAG ACACGGAACG TGATTCCTCT TCTTCCCCAC AAGCTTATAG AGAGACTTCA TTAAGTTGAA AGTCAACATT CCCACCTAGC TTTGCACTTC AAACGACATA TTCAAAAAAG CCCAAACTTC CTCTAGTTTT CTTCATCTGA GTAAATGGTT TCACAAACTG AAACCTTGAA TCCTCTCTGT CTCACACACC CGATCAGTAA GTTCTATTGT TTCTGATTCC AAACTATGTC TTGAATCAAT CCGTTTATCT CCATCCTCAT TGCTACCACT CTGATTCCAA ACCCTTATCA CCTCTCACTT GGAGTATTAA TAGTTTCCTT GTTTCTACTC ATAATTCATT ATTCCAAAAA AGTTAAGAGG GGAAAAACAT AGATCTCGTC ATTTCCCTTT TTAAACCACT TTACCTTCAA GGTTCCAGGT GATCTAAGCC TTGCCCTTCT

CTCATACCTA GTTAATTAAC TACACTCTGT TCATGAATAC ATTAGGCTCA CCTACCTCAA GATCTTTTTG CTGAGCCTGA TTTGTTCTCT CAGCCTTTTG CATATTTCAT GTTTATGTCT TGGCCCAAAT GTCACTTCCT TAGAGGGGCT TTTTCAGAGC CTTCAATCTT AGGCAGTTCC CCCAAACGCA GTCTTACACT TGTATCACAT TGGCCTGTTC AGTTTTCTAA AAAGCACATT ACCATTAAAA GAAATGCTCT TGTTTGCTTT GTATATTTTC CACTTCTACA CATTATGTTG CAAAGTTCAT AAAGGCAGGA TGTTGATTTT CTTCACAGCG TTACCCTCAG CACCTAGAAC AGTGCCTGAC ACATAGTAAG CATTCATTAA AGGGCTAAAA ATATTTCATG TTTTAAAAAT ACTTGGGAGT CTAATTAGAC AATACTTTTT TTCAGCTTAA TGGTAGTATT TTAGCTTCAC TATTTTAACA AATGAAAAAT TTGCAATAAA TCTACAATGC CATTACCCCC CAAAATCTTT TTCATGTTTT

GCATTTTACG TATTATTTTC CAGGCCTTAC CTGCATGTCT GCATAATCAT AACTGACTAA TTTTGGAACA GCTGGTAATT ATTTGAGCTT TACTGAAATT TTTTCATGAG GCCAATTCTA CCCTACTGAA CTCAAATTTG AGTTAATGAT GACCTCATTT TGATTGCTGC TGTAAAAAAT AAGATTTCGG AAGAGGAATG AATTCTTGTA TTACTGTGGT AGGACTATGG GTTTTTTTTT GTTTGTTTGT TTGTTTTGAG ACGGAGTCTC ACCCTGTCAC CCAGGCTGGA GTGCAGTGGT GCGATCTCAG CTCACAGCAG CCAGGTTCAA GTGATTCTCC TTCCTCAGCC TCCCGAGTAG CTGAGATTAC AGGCACGTGC CACCATGCCC GGCTAATTTT TTGTATCTTT AGTAGAGATG GTTTCACCAT GTTGGCCAGG CTGGTCTCGA ACTCCTGACC TCGTGATCCG CCTGCCTCAG CCTCCCAAAG TGCTGGGACT ACAGGCGTGA GCCACCGTGC CCGGCCGGGT TATTCATTTT TCTTATTAAC

ATTCTTTGAT GATTCTTATG GTGTTGTTAC AGTAAAACAT TTCTAACAAT TATTCTAACA ATTATTCTTG ATGGTGTATA TGAAGAATTT ATTGTCGTGT ATTTGTAAGC TGCTATGTGC AGAAGAATTT CAGTCAAATA AAGTTGGTAA GATAGGTATG TAAGTAATAT GAAAAAAGAT AGAAGGTGAT GAGTGACTTA GGTATAAATT AAGTACAATA GAAATGTTGA GGAAAGAAAA ATTTCTTGTA ATAGAAATCG GAAGTACAAA CTGGGCATGG TGGTGTGCAT CTCTAATCCC AGCTCCTTGA GAGGCTGGTA TGGGAGGATC ACTTTAGCCC AGGAGCTTGA GGCTGCAGTG AGGTGTGATC ATGTCACCGC ACTCCATCCT GGGTGACAGC AAGACCGTCT CTCTTTTTTT TTTTTTTTGA GACGGAGTCT CGCCTATGCT GGAGTGCAAT GGCGCGATCT TGGCTCACTG CAACCTCTGC CTCCCAGTTT CAAGTGATTC TCCTGCCTCA GCCTCCTGAG CAGCTGGGAT TACAGGTGTG

CGCCACCATG CCCAGCTAAT TATTTTGTAT TTTAAGTAGA GACGGGTTCT CACCATACTG GCCAGGCTGG TCTTCAACTC CTGACCTCTT GTTCGCCCAT CTAGGTCTCC CAAAGTGCTG GGATTACAGG TGTGAGCCAC CCCACTTGGC CCCGAGCGAG ACCCTCTCTC TAAAAAAAAA TAAATAAATA AATCATAAAC CTGTGGATTA TTGTAGCATT GTTTCTCATC TGTCAAAAAT ATTTCATGAC TATGCATAGT TTGAAAAGGC AAGTTTGTCC CTGGGCAATT TTCAAAATAT TTCTTTAATG TGTTTTCACA ATACTGTTTA CCTAATAAAT CTTAAGTTTT TAAAAGCAAA ATTAAGCCAG TAATTTGAGT CCAATTCCAA TCTCTTATGA GTCATTGCTT AAATTTCAAA AGGGTTTTAT TTTTTTTTTA GGTTTGTTCT GAGTAATGAA TACCCTATTA CTATGATACT AGTATCTTCC TTAATTATCC TACTCATTGT CTCAACATTC TGACAGTTGG ATTGAGCATA TTCGTAAGTA

AAATTGTTTT AACTGTATGA TGTACTTTGA TGTTAAGGTC CGAGTCCCCA CATACCTCGG TAGATGTGTT CTTACAGTTT TGTATTCCCT TGAAATGTAA CTGTTCTCTA TGTTACAGCC TTTATAACCT TCAGTTACTT GAAATGAACA AATTCATTCA AATTCCAGCA CTTAAAAGTT TTAAATTACA TTTTGGATAA ATACCAAAGT GTTTTGTTGA TGATGTATGT ATAAACAAAT TGTAAATATT AAACGTTAGT TGTTACGATT AGACCTATAT AAAACATGAT ATGCAGTCTA CTGAATAGCT ATCAGCCTCT AACATGTTTA GTGTCATTTA GAAAATGCTT TCTAAATTGC CAAAAGCTGA TTGTCTAGGT GATAACAAAT TTACCATTTG GAGGAAGTTG ACTTTCTCAT TTTCATGTCT TCATCAGTCT TACTTGATGA GATTCATTCT TCTAGTCAGA AGAGAGTTTA GACTGCTCAG TTTACTCATA TTTTGAGTTA GCTTTTCTAT TTAGAGTTCA CTTGGTTGTG GAATATTCAT

TTATAATTTG AATCTACGTT GTGTAATGGG ACCTAATTTT TTTTTCCTTT GTTTTTGTTG GAGTCTCGTT TTGTCACCCA GGTTGGAGTG CAGTGGCGTG ATCTTTGCTC ACTGCAACCT CCACCTTCCA GGTTCAGGTG ATTCTCCTGC CTCAGTCTCC CAAGTAGCTG GGATTACAGG CATGCTTCAC CACGCCTGGC TAATTTTTGT ATTTTTAGTA GAGATGGGGT TTCACCATGT TGGCCAGGCT GGTCTCAAAA CTCCTGAGCT CAAGTGATCC TCCTGCCTTG GCCTCCATAA GTGCTGGGAT TACAGGCGTG AGCCGCTGAG CCTGGCCCCA GAGTTTGTTT TGTTTTGTTT TCAAGACAAG ATCTCACTCT ATTGCCCAGG CTGGAGAGCA GTAGTGCGAT CATAGCTCAC TGCAGCCTGA ACTCCTGGGT TCAAGCTATT CTCCTGCCTC CATCTTCTAA AGTGCTGTGA TTACAGGTCT GAGCCATGAT GCTTGGCCTG TGTTTTTGTT TGTTTGTTTT GGGGGACAGG GTCTTGCTTT

GTCACCAAAA CTGGAGTGTA GTGGTGCGAA CATAGCTAGC TCACTGCAGC CTCCATCTCC CACGCTCAAG CAATCCTCTC ACCTCAGCCT TCCAAGTAGC TGAGACCGCA GGTGCGTGCT ACCATGCGTG GCTAATTTTC TATTTATATA TTTATTTTTT GGTAGACATG AGGTCTTGTC ATGTTTCCCA GGTGGTCTTT AACTCCTGGG CTCAGACAGT CCTCCCGCCT CAGCCACCCA AAGTGTTGGG ATTACAGGCG TGAGCCACCA TGCGTGGCAT AATTTTTTTT AAGTAAATTA TTTTTTTATC TTGAGTATAG AAGTGATTCA TGTTCATTGT GGAAAATATG AAACATATAG AAAAACAGAA AAGATTACAA AACATCTAAT CTGAAATGGT TAAGATTTTG ATGAGAACAG TCTCATCTCA TTTCCGTATA TTCCTGCCAG CCTATCCATC ATTCTTCGTA CATGTTTATC TACATTAAAA TTGGTGTTAT ATTTTGGAAA CTTTTTGTTT AACTACATTG TGAACATTTT TCATGTTTTA

AAATGTCATT TTAATGATGG CAGATCCTAT TCAATAGATG TACACACACC TATTTAACTG GTCCACAATT GTTGGATATG TAGGTCGTTT CCTTTCTCTC TTTTTrrTTT TTTTTGGCTA CTACTTAATA GTTTCTCTGT ATAGAATGTG GTATTTTGAA AGTGTATCAA GCTTTAGATT GGTAGTATTC TTGCATTTAA TAAAGGGCAG TGGCCTTTGT TGACTGACAT GACAATATTT TTATAAAATT TGTTATTTGC TTTACAGAAA TTTTGAAAAT TATTGTAGAA ATGTTTTTAC CTCATATGAA CCACCTGACA TTGGAACAGA CTTTCTTTTC ACAAGTGTTA CCAAAGGTAT AATACTATTA CCTGAAAATA CATGTTATAA GGAATCTAGC CTCAGTCTTA GATGATTTAT TATTAATTAT GGCTCTCTTT TTCTAATATA TCAAATATAT TCAAAATAAA AATAAGGAGT AAGTAGATCT CATGTGAGAC TATAATGGTG TTAGTGTGAT CATTAGGCAG TTAAAAACTG TTACAGGCTG

GGCACGGTGG CTCATGCCTG TAATCCCAGC TCTCTGAGAG GCTGAGGTGG GCAGATCATC TGAGGTCAGG AGTTCGAGAC CACCCATGGT CAACATGATG AAACCTCGTC TCTACTAAAA GTAC AAAAAA TTAGCTGGAC ATGGTGGCAG GTGCCTGTAA TCCCAGCTAC TTGGGAGACT GAGACAGGAG AATTGCTTGA GCCTGGGAGG CGGAGGTTGC ATTGAGTCAA GATCGTGCCA TTGCACTCCA GCCTGGGCAA TAAGAGCGAT GCTCCGTCTC AAAAAAAAAA AAAAAAAAAA AAGAACTTAT ATTTTCAGAT TGTGTGGTTC CTTTACTAAC TGAATTTAAA TTATTTGTAG TCAATTTTAA ATGCTCTTGT ATTTTAAAGC CACTGTACTC CAGCCTGGGT GACAGAGTGA AACCCTTAAT TCAAAAAAAA AAAAAAAAAA AAGAAAAGCT GGAATATTGG CAAAATCAAG TAACTAAGAG AAAACATTAA ATTCACAGAA TACATTATTA CATTTTAGAT ATATATGGTA TATGTTTTCT

CTGAAAAGCA CAAGCATACC TTTTTTGTTT TAAATGGAGG GAACTAAAGA TACTTTGGTG CCAAAATGAA ACATTATTTG TAATTAATCT CTTATTGAAA TGGGTTTCTA ACTTTAGCTT TGAATCGTAA TCTTTCAAAT TTCTTGTACT CATAGTCACT TGATGATTCT CTATCTGAAA TATTTCTTAG AATTTGTTCT TGACCACCAG AAAAAGATTC AACTGTTACA TAGATGAAAA TGGATGTTGA GTGTTAACAG GCCTATGGGA AACAGTATTT TCTTTAGCTA CATTGTATTG TTGACTGTGT TGCTATTCTT ATAATGTTTA GGTCATTTAA ATTGTTAGAA AGATCCAAGT ATTAAGATCT AGGGTGGCTA ACTTTTCACA GACAAAAAGC TTGTTTGTAA GGTCATTTAC TATACCCTTA ATTCAGGAAG GTTAGCTTGA ATTGGGTCAA AAGGAAACTG GTTAGAAAAT AAGTGAGTAG TGAATAGGCG ATTCAGTGCA AATTCCTTCC AGAAAATACC CTTGTAAATG ACTGTATGAA

TGTGGATTCT TCAAGACAGT CAAATTTATT GTGCGAAAGT AATACTTTTA TTTTTTGCAT CTCTAAAACA TGAACTTTGA GTGATTTTTT AAAAAAATTG ATGCTATTAA ATAGATTCAA ACCATAGAAA TGGAAAATAA ATTTCTGTTT GGGGCTTTTG GGGGGATTAT GTTGTAAAAA TACCTTTTCT CTGTATTTTG TGCTTAATTA GGTACAATTG TTAAGCTAGA TGATAGCCTG TGGATGTTAC TAGTGCAAAA TCAAATTATC GTATTGTGTT TTCTCTGTAA AGTTTTGTCT TGTCTTTTCT AGTGATTTCT CTTATTCCTG TTTATTACTT GATTTGTTTT TACAGACTGT GAAATTATTC GATGACATGA TGTATGAATT AACCAGTCAA GCCAGAGGAC TGTCAAGCCA AAATTTGGAA ATCCAGACCA CTCTAAGGAA TATTTTACAA GTAAGTCAAA TGTATTAGAA AGCAGGAGAG AGAGGGAGCT TAAAGAATGT CAAAATTTTT ATACTGATAC TGATTAGCTA TGTATTCTTA

TGTAATGGCC TAATGTTGGA ATTAAATTTA TAGAATTAAA GACGTGAATA TAGAAACATG AATTCTGAAT AATAAACTCT TATAAGAAGA GAAGTCATCA AGCTAGCTGA CCCTACCTGT ATTTTCAAGG ATATGTGTGG AACACCTGCC ATGTGTTTTG AAGTTTGTGT TAGTATTCTA AATGGCTAGA CAGTTGTTCC AGTATTTGTA GTTCTGATAG ACTAAAGTTC TGTGAAAAGA GGAAGAGACT GTGTTTTGTT CATTGCTGTA TTTGTAGCAC CCAGCATGCT GACTAATACC TTTTCAGTGC ACAAAAAATA TATTCTAAGT GAAATTTCCT TCCTTATTCA CAGACAATGG TGCAGCTCTT AGGAGCTCTC ACAGGATGTG TTCAGCATAT CTGTGCCACA CAGGAATCCA TCATTTTGGA AAATATTCAG AGTCTCCCCT CCTCAGTCCT TCATATAATT AAAAGCACAT TTGTGCATTG TAAGGTGAGT AAAGGTCTAA TTATACTTTG AATGGTATAT AATCAATGTG CATAGGGGCT

GAGTAAAATA ATGTTTGTAT AAGATTTTAC ATTTTAGTCT ATATTATTGA AATAAACTTT TCCATAGAAT AAAGAACATG TAAGTAAATA ATTGTTGCAA AAAAAGTGGT TTTAAGGAAG TCATTAAAAG TGGCTTTTTG GGGTTTTTTA GTTTTATCTT ATTTCCCCTC TATAAAGAAA GAAGTTTTAA GAATTTGTGT TGAGACAGAC ACAGGGATCC TGAAATAGTT ATGTCATGTT GCATTGACCA ATATTCAATT ACCATTATGA TTAGATGTCA GAACTTCCTT TTATAAAGGA AAGTTAATCC TTATTTAGTC CATCTCTACA TGCCAGAGGT AGCCTTGAGG CACAAAAGCT TGCCTAGAAT TTATGGGTCA CAGACAGTTT TAATATTGCT ATTTGTTGGG CGAATGAAAA TCACTAGTTA ATTAATACCT CTCTTTGCTG ATAGGATGCT AAAAATGTCA CGCACCTGGC CTAATGTTAC CCTTTTTTAG TTCTGTATTT GCAAGATCAT GGAAGTCAGA AATAATATTT TATACATGCT

TGCATCTCTT GAAGCACACT ATATTTAATG GATGTTCACT AAACAATGAA TGAATATGTG ATTCAGTAAA TTTATGATCT CTAATAGTAT GAATTAAAGT AAATTTGGCT CTTGAGCTTT GATTTGTTTT TTCTCTCATT TTTATTTATC CGTAATCAGA ATAGTGAATC TGTGTATTCT GGGTGTTTAC ACCTAGTTTC AGACCTTCTC CAGGCTCTTT TCAAGGAGGC CTATTCTCTT CAAAAGCAGT TAATGGAACT GCTGGACATG GTTTGCATGG ACCCTTTAGT AGATGACAAT GATGATATTT TGAATATGGT AATAGGTGAG TGAAGAAAAC TTTCTGCTTA GTATATGGTG ACTATAAATC ATGTATCAAT TAAAATTGTC TCTAATGATT CATGTTATTT TCTTACTAAT TATGCATTAA AATTGATTTA AATCTTACCA AATAAATTTT TAATCTTGAA ATTTGGAATT TGTAAAATTT ATTTTGGGTA CCTTAACCTA GATTTGCGTA TTTAGTTACT GTAATTTCTC CACAATGATT

AACTTATATA ACTTTATAAT CTCTGAGGTT GTCCATATTC AGAGACAATA ACTTTCACAT TTTTTTAACC ATAACTGATA TTGAGATGCA GTTTATATTT CCTTCCAGAA TACATATAAA TACGTGCATA TGTGTATGTA AATATGTCTA TTCTCATATA CATATTATAA TGAAATAACT CATTTTACAT GTGATGCACT TTATACTAGT TTATTTTTAT TTTATTTTAT TTTTTTGAGA CAGAGTCTCA CTGTGTAGCC CAGGCTGGAG TGCAGTGGCA CAATCTCGGC TCACTGCAAC CTCGCCTCCC GGACTCAAGC GATTCTCCTG CCTCAGCCTC ATGAGTAGCT GGGATTATAG GCGTCCGCCA CCACACCTGG CTAATTTTTG TATTTTTAGT AGAGACAGGG TTTCACCGTG TTGGCCAGGC TGGTCTTGAA CTCCTGACCT CAGGTAATCC ACCTGCCTCA GCCTCCCAAA GTGCTGGGAT TACAGGCATG AGCCACCGTG CCCAGCCAAT ACTAGTTTAT TTTTAAAGAA TTGCTGGTCG

TAACACACTT CATTGATTTT ATCACTCATT AATGGATTAT GAACAAGAGT TTGAAAAACA ATATAAAGGC AAAGTTTGCA TTCAAAACTT TGGTATAAAG AGAGTAAGTT GGTTTTGTGC AGTGTATCAG GCACCTGTTG CTCTGCAACA CACCACCTCA AAATCTATTT ATTCACTATT TATTTATTCA TGATTCTGTG AGTCTGCAGT TTAGGGTGGG ATGTCCTGAG ACAACTTTCT CTGATCCACC TGGGGCACTA GCTCACCCAT GTGACTTCAG TGACTTCATT CACATCTGGC TGTTGGCAGA GGCAGAAGTA CTTGAGAAAG CCATGTGCAT CATCCAGCAG GTTCACCCTA TCTCAGATAC CTGATGCCAG TGGTTTCAGG GTTTCTAAGA GTAGCAAAAG TGTGAGCAGG TCGCTGTGTG CTAGCACTTT TCAAGTTTCT GCTTGCCTTA ATTTTATTAT TGTCCCCCGG GCCACAGCAG GTCATAGCGT TTAGCCCAGA GTCATTGTAG AAAAGTGTGG ATTCACAAAG GGCAGTCATT GTGGCCATTT TTATAAATAA TCTACCACAG ACTGAGTAAA AGCCTTGCAT GAATACCATG GATATTAATT TGAATTCTTC CTTTTTAGAT TTTCTTTCCT TAGCAATTTG TTTTGTCATT TTGGATTAGA ATTATATCTG TAGAATATTT CAGTTATAAT AGGGTACAAC TTTTATTCCA CTGAACATCT TTAGTTTTAT TTAGGTCATC TGGTAGGTAT AAACTTCAGA AGTTAATATT CAATATTTAT AAAAACCATT AACAAGTGTG ACACTTAAAT AGTTTAAATA ATTCTTTTGA CACAACTGTT TCCAAGTTGT GTTACGTATT TTAATTCAAT CAAATGTTGA AATTGTTCAG TAGATAGTTT TAATTATAGG AGAAACTCAC CCCCATGACA TTTGGATGTC TTAAAAGTTC TGTTATCTTT CTTTGCAGTT

ATTCATTCTT TATTGGATAT CTGCTCTGTT ATTTCCAGTA TGGACCATGC ATTTCATGCC AATACTTGGA AGTTTATAAT TAAGTAAGTT TGTTTGTTAT TTTTTACTTT TTAGAAAATG TTTTCCATAT TCCCCAATCT TAATTATTCA TGATTCTTTA GATTGCATTT AAAACATTTT GTGTGAATTT AATGTTCACT GACACTGCTG TCTGATAATC CAGATATTCT ACATGTAGCT CTCAAGCCAA ATTGGACTTC TTTACCCTGT GGCCTCTAAA ATTAAAAAAA ATGTTCTTCC TAGTTAGCTA GTACTTCAGA AATAATGGGC CATGGGCCAG ACTAGAACTT AACCACTTTT CTTCTGCTAC TGTTGTTTAA CCAGCTATCA AGTATCCTAT TTCTAGGATT AGATAAATTG ATAACTATAA TTAAAACTGA ATATAATCTT TTCATTAGGT ACTTTTAAGT TGTTCACACT TAATTCCATT TGTACAGTAA TTTTAACTTT CTGAAACTGA AGCATTTTAA AGGGTCACCA GGGATAGTGC

CTGTAGCATT CATCAGATTC TTAGGGGTGA GAGGAGATGT GGTTGAGATG TAAAAATGGT TAAGAATATC TACTTTATAC ACATACATAA AACATTAAAG GTCAGTGTAT TTTCAGGTCT TAGGTACTTT TCTTGTACTA CCAGGACATT AAGTTGCCAT TCAGTGGTTA AGAGTGTTGC CTGGGAGCTG TATCACATGT GCTTAAATCC ATTCTTGAAA TCATTTACTC CTTCTGAGCC CTTGGGCTAT TTGGTTAATT TCTCTGAACG TTAGTTTGCT CATCTGAAAA TGGAAATAAT AATAGCAACT TCTTGACAGG GTTATAGTGA GAATTGAGTT CATCACTGTG AAATGCTTAG AAATGTGCAT GACACATAGT TAATACTCAA GGAATTAGCC ACATCACTAT CATCATCACT GATTATCTTC CACTCTTACC CTCTTCCAGT TCATTTTCTG CCCAGCAGAA TGATCTTTTA AAAAGTAAAT CAGATCATGT TACTCTATTG CTTGAAGTCT ATCCCATTTG ATTAAGAATA ACAACCTAAT

CCTCTGTGGA TGCTGCCTCC TTCACCAGCC TGTCTCATGC TGCTCTCCCT ACTCTTAGTT CCTCAAACAT ACCAAACTCT CCTGTCCCAG AGTCTTTTCG TGGTTTTTCC ATCTGCCTAG GATGCTTCTC TCTCCTATTT TGTGTACCTT GCTAACTCCT GCTTACTGTC TTTCAGTTCT CAGCTTAAGA GTTATATCTT CATGATAACA TTCTTTGATA TCCTTACCCT AAGATTAAGT TAGATTGATA TCCTTACCCT AAGAATAAGT TAGATTAGGT CTCTCTATTG TAGCACCTTA GACTCTGTCA TTTGACAAAT CACAGCCCTA ATTAATTATT CTTAAAATTA TTTAACATTC TCTCTCATGC TAGACCACAA GTTTCATGCA GGTAAGGCGG AGATTGTGTC CATTTGTTTG ACCCCTTTGT CTCCAGGGCC TGGTAGAATG CCTCATACAT AGTAAGAATT CAATTAATAT TTTACACAGA GAAAAAATTA GCAACTTATT TAAACAAATA TAACTGCTTC AGAGGTAAAC TGGGCACATC

TTAGTTATAT TATGTGATAT ATGATGCTTT TTGATTGTTT TTTTAAATGT TCTACAAGGT AGATATTGTT AGAGGTCCTA AGTTACTTGA TGTGTTACTT GTGGTGATTG TATTCTTTTC TTTTTATTCA TTTAGGCAGA GCCTTAAGCA CCAGTCCATA ATAAAAAGCC AGTTGAAACA CAAAGATATA ATTACTAGCT TGTGTGAAGA CATTCTTTTC TCCTTCCATT CTTGTTTACA GTTAGCTGAG CAGATGACAC AGTCAGATGC ACAGGTAAAA TTTGGGCTAA TAGCATTTTA AACAGCAACT CTTATTTTCT TTGGCAGTTA GTAAATCTCA TTTGAATGTC TGGGTCAGTC TATTTAAGAG GATTTTAATT TATTTCATTT GGGTGTTTTT TTTTGATCTG TGGGATTATT TATATCCCAT AATTACTTTT CACCCAGAGC ATTGTATTAG ATTCCTAACT GCTGTCATTG CCTCTGGGGT CTGCCTGGCT CCCTCTTTGC TTGGTAACTG GTTGGTCACA GCATTCTTCT CAGAATCCTT

TCATTCTTTT CTGCATGAGA ACAAAAATTC TTTTGTTCAT ATTTGTATAA GATCTGATAT AGCTGCAATC AATCTTGCAT TTTTTCTTCA CCAACGCATT GCGACCTTTA GGGATACAAG TATGTTTGTG CATGTATATG TATGTATCAG TCTTTTAAAT TTGATATAGT CATACATTTG TTTTTATTTT GAAAAGTTAG AGTGTTGAAT TGGTATCCCA TTTATGAAAC ATTATATTCT AAAAATTTGT AGTACGATTA TTGGGAATTA TAACTCATTT TCCTGTAACA CTGTTATACA TAGTACCTTT TGCTTTCAGA CTAGCCCTCA ATTTTATTTA ACTATAGTAG TCCTAAATTA TAAGATTAAT AGTACTCAGG ACCTAACAGT TATATGTCAT TTGTTTTTTT TTTTTTTGAG ATGGCGTCTC ACTCTGTCAC CCAAGCTGGA GTGCAGTGGT ATGACCTTGG CTCACTGCAG CCTCTGCCTC ACGGGTTCAA GGGATCGTTC TGCCTTAGCC TCCTGAGTAG CTGGGATTAT AGGCGCCTGC

CACCACGCCT GGCTAATTTT TTTAGTAGAG ACGGGGTTTC GCCATGTTGG CCAGGCTGGT CTCGAACTCC TGACCTCAGG TGGTCCACCC GCCTTGGCCT CCCAAAGTGC TGGGATTACA GGTGTGAGCC ACCGCGCCCA GCCTATATGT AATAATTTTA ATGGGACCAT GAATTGAATA TTTCTTCCTT GAATAGCAAT GACATAGCCC CTTCTATTGT ACATCTGCAA GCTGATACAG GGAATTCCTT TGTACCTGCG CTCTTCCCTG CCAGTCAGCT ATGGGGGTGA AAGTGTAGGG GTTCATCCAA GTCCTAAAAC TGGTAGCAAC TCCTAGGGCA GGGCTGATCT GGAAGGACAG ACCCTAGGGG AGGGTGGAAC TTTAAAAAGA AGTTCTGAAG GTAGTAAGAA GGAAATGAGG AGTAGTGTTA GGAAGGGGCT AACTTTTTTC TTCTTGCTTC TCTTCTTTAT CTCACCTGCC CCTCCCCTTG TATCCCTTCT TCCTTTTTCC CTTTCCTTTT TTGTCCTCAC TTCATTCGTG

CATCCTTTCT GATTCCTCTT ACCTTGCTAA AAGGAGAAGT TTGTTTGGGT ATCCTATATC AATGGCAGGA AGGTTGTTTT CTTCTTTACC TTTATCCTAT AGATTCATAT TCTCAACACC AACCTCCTCC TTTTTCAGTT TCCTTCTTGC TTCTCTTGAC ACCACAGAGT TTGCAGCTAG TACTTGGAGA GGAAAATTAA ACAGAGATAC TTGGACCAAG AGTAAGATGA AGAAAGTCTA AACAACAGTA TAGTCTATAG TGGCAAGAGA GAGTATGGGG GCTGCTTAGC CAGGGTGGCT GTACATAAAG TATATCTTCA GTTTATATAA ACTGCTTATA GATGGAAATC AGAAAATTTA AATTCTCTTA ACTGTCCAAG AAAATTCTCA TTTTTTCAAA TTTGGGACTG ATAAATGTGA CCAGTTCTGC TTACTGTCCA TTGCCTGAAA TGGAGCTTTG AGGTGGACTG TATAATTTCT TCAATCTTAA CTCCAAATTC TGATCAGCGA CGCCCTCTGC TGTTCACTAT TAATATTTAT TTACCAATCA

AAGTAAAGTA TTGAAGTTTT CCTGGCAGTT TTCACTTTGT GTTTTAGTCC ATTTAGGCTG CTATAACAAA ATCCCTTAAA CTGGGTAAGG GATTATAAAT ATTAGAAATT TATCTCTCAC AGTTCTGGAA GCTGGGAAGC CCAATATCAA GGCACCAGTA GATTTGGTGT CTAACGAGGG TGTGCCGTCT GCTTCAAAAA TGGCCCCTTG TTGCTGCATC CTCACTTAGT GCAAGGGGCA AGACAGCTCC CTTCAACCTC TTTTATAAGG GCACTTATGT CATTCATGAG GGCAGAGCCC TCATGACTTA ATCACTTCCC CAAAGGCCCC ACCTCTTAAT AGTATCACAT TGGGTGTTAG GTGTCTGGGA GGACACCAAT CTTCAAGCCA TATCATCTCA CTTGGAAAAA AGTCAAAATA AAACCAGTAG ATTTAATTAA TATTACACTA TTTATAGAAG CATGTGATGT ATCATTCCTT GTATTAATTT CCTGGGGTTG CCGTAACAAG TTACCACAAA CTAGGTGGCT TAAAACAATA GAATTTTATT

CTCTCACATT TCTAGAGGCA GAAGTTCACA GTGTGTCAAT AGGGCCATGT TCTCTGGAAG GCTTTAGGGG AGAATATATT TCATATCTTT CTCTTAGCTT CTCGGTGTCA CTGGCAATCC TTAGCTTACT TTGGCTTTCT GTGTCTTCAC ATCATCTTTT TATAAGAACA CCAGTGATAG TGATTAAGGG CATACCTTAC TTTAATATGA CCTCATCTTA ACTAATTATG TCTTCAATAA CCCTATTTCC AAATAAGGCC ACATTCTGAA GTATTGGGAG TTAGAACTTA AAGCTTTTTG GGAGGGACAC AGTTCAACCC ATAACAACCC CTAAAATCGA TATTTATTCT CAATTAAGTC TTGAAATTGG TTTCAAAAAG AGAATATTCT ATTAGAGTTT TTAATGTATA GTTTTAACAT ATAGTTCTTT AGCCCCCAAT _{ττrrnτrrτ ττrτττττττ ττrrrrτrrr τπττGAG C} GGAGTCTCGC TCTGTCGCCC AGGCCGGACT GCGGACTGCA GTGGCGCAAT CTCGGCTCAC TGCAAGCTCC

GCTTCCCGGG TTCACGCCAT TCCCCTGCCT CAGCCTCCCG AGTAGCTGGG ACTACAGGCG CCTGCCACCG CGCCCGGCTA ATTTTTTTGT ATTTTTAGTA GAGACGGGGT TTCACCTTGT TAGCCAGGAT GGTCTCGATC TCCTGACCTC ATGATCCACC CGCCTCGGCC TCCCAAAGTG CTGGGATTAC AGGCGTGAGC CACCGCGCCC GGCCTGCCCC CAATTATTTA GTTTTTCTAT AAACAGGGAA ATTTATTTGT GTGGCCCTTA GAACTAATTT AATTTCCACT CTAATTCCTA CTTATGTTTA TATAATGCTT TTAGAAATTT GTATTATTCA GAAAATAAAC ATATACTATT GTATCTGTTG CCTACACTTA GATTTTATTG CCTGCTATAT TTAAATTTTA TTAGTATTTT AATTGTTTTA TTAAAGAAAG AATGTGCCTG TAATCTCAGC ACTTTTGAGA GGCCAAGGCA GAAGGATTGC TTGAGCCCAG GAGTTTGAGA CCAGACTGAG CAACACAGGG AGACCCCCAT CTCTACAAAA

AATAAAAAAA TTCTCCAGGC CTCATGGCAC ATACCTGTAG TTCTAGTTAC TTGGGAGACT GGGGTGGGAG GATGCATTGA GCCCAGGAGA TTGAGGCTGC AGTGAGCCAT GATCAGGCCA CTGTACTCCA GCTTGGACAA CAGAGTGAGA GCTTGTCTAG ATAGATAGAT AGATAGATAA TCTAAATAGA TAATAGACAG ATTATCTAAA TAGATAATAG ACAGATTATC TAAATAGATA ATAGACAGAT TATCTAAATA GATAATAGAC AGATTATCTA AATAGATAAT AGACAGATTA TCTAAATAGA TAATAGACAG ATTATCTATC TAAATAGATA ATAGATTATC TAAATAGATA ATAGATAGAT AGATTAGATA GATAGATAGA TAGATAGAGC TTGGACAACA GAGTGAGAGC CTGTCTAGAT AGATAGAAAC AAAGAAAGAA AGAAAGAATG GTGCTCATAT TTTAAAGCAT TGAAAAATGG TCTTCCTTGC TTATATTACC CACACCTTCT TTGTTGGCAT TAAGATGCAA ACTTTGTTTT

AAACAGTTGA GTAAATCAAA GATGGGACTG TTAAGTTATT TGTGTTATTT ACCTGCTTTT TGAAAATGTA AAAATAAAAC TCTAGGTTTA ATTAGTAGTA TGCTATTTAG TAATGAAGTA AAGCTAGAGG CTTCGAACAA ATCTTGTGTA ATTTCCTCTT GAATGAGAGA GAAAATTTAA AGTAAGCAAA CAAATAAGTT GTGTGTCACC ACTCATTCAG TCATTTAACA AGTATTTCCA GAGTACTTAT TCTGTGCCAG GAAATGTTGT AGGTGCCCTC AACAACTTAG AGTCTAGCCT GAGACACAAG TAAGTAGGTA ATTATTATAG AATGGTATGA TCTTTGGAGG ACTGGGTATT GGCTGGCTCA TGGGAGTACA AGATAGGTAC CCAGTGATGA AGTCAGGAAA GGTTTCTTAT GGTGATATGA TGACGTCTAT GCTGATTATA AGGTCAGTGT AGAATAAACT TTGTGCTTTT AAATTTGCAT AGCACTGTAT TAGAGAGTTC ATCTTCAAAA TAATCGAAAA GGCTGAGTGT GGTGACCCAT

GGCTGTAATC CCAGCACTTT GGGAGGCCGA GGTGGGCAGA TTGCTTGAGC TAGGAGTTCG AGACCAGGCT GGCCAACATG GTGAAACCCC GTCTCTACTA AAAATACAAA AATTAGCCAG GAGTGATGGT GCGCACCTGT AATGCCAGCT ACTTGGGAGG CTGAGGCAGG AGGATCACTT GAACCCAGGA GGTGGAGGTT GAAGTAAGCC GAGGTCATGC CACTGCACTC CAGCCTGGGC AACAGAGTGA GACTCCATCT CAAAAAAAAA AAAAATGATC AAAGAAAGGT GAATTTTCAT CTACCCTATT TCTGCTGAGG AAAATGGACT ATTTTCAAAT ATTTTTAATA AGGGTCAAAA TGAGGGATC GCATTTTTTC AAGTTTTATG ATTTATTTAA CTTGTGGAAC AAAAATAAAC CAGAAACCAC CACCTCTCAC GCCAAAGCTC ACACCTTCAG CCTCCAACAT GAAGGTCTCC GCAGCACTTC TGTGGCTGCT GCTCATAGCA GCTGCCTTCA GCCCCCAGGG GCTCGCTGGG

CCAGCTTCTG TCCCAACCAC CTGCTGCTTT AACCTGGCCA ATAGGAAGAT ACCCCTTCAG CGACTAGAGA GCTACAGGAG AATCACCAGT GGCAAATGTC CCCAGAAAGC TGTGATCTTC AAGACCAAAC TGGCCAAGGA TATCTGTGCC GACCCCAAGA AGAAGTGGGT GCAGGATTCC ATGAAGTATC TGGACCAAAA ATCTCCAACT CCAAAGCCAT AAATAATCAC CATTTTTGAA ACCAAACCAG AGCCTGAGTG TTGCCTAATT TGTTTTCCCT TCTTACAATG CATTCTGAGG TAACCTCATT ATCAGTCCAA AGGGCATGGG TTTTATTATA TATATATATA _Tχ χχχχχχχ AAAAAAAAAC GTATTGCATT TAATTTATTG AGGCTTTAAA ACTTATCCTC CATGAATATC AGTTATTTTT AAACTGTAAA GCTTTGTGCA GATTCTTTAC CCCCTGGGAG CCCCAATTCG ATCCCCTGTC ACGTGTGGGC AATGTTCCCC CTCTCCTCTC TTCCTCCCTG GAATCTTGTA AAGGTCCTGG

CAAAGATGAT CAGTATGAAA ATGTCATTGT TCTTGTGAAC CCAAAGTGTG ACTCATTAAA TGGAAGTAAA TGTTGTTTTA GGAATAC ATGAAGGTCT CCGCAGCACT TCTGTGGCTG CTGCTCATAG CAGCTGCCTT CAGCCCCCAG GGGCTCGCTG GGCCAGCTTC TGTCCCAACC ACCTGCTGCT TTAACCTGGC CAATAGGAAG ATACCCCTTC AGCGACTAGA GAGCTACAGG AGAATCACCA GTGGCAAATG TCCCCAGAAA GCTGTGATCT TCAAGACCAA ACTGGCCAAG GATATCTGTG CCGACCCCAA GAAGAAGTGG GTGCAGGATT CCATGAAGTA TCTGGACCAA AAATCTCCAA CTCCAAAGCC ATAA CCACATATTC CCCTCCTTTT CCAAGGCAAG ATCCAGATGG ATTAAAAAAT GTACCAAGTC CCTCCTACTA GCTTGCCTCT CTTCTGTTCT GCTTGACTTC CTAGGATCTG GAATCTGGTC AGCAATCAGG AATCCCTTCA TCGTGACCCC

CGCATGGGCA AAGGCTTCCC TGGAATCTCC CACACTGTCT GCTCCCTATA AAAGGCAGGC AGATGGGCCA GAGGAGCAGA GAGGCTGAGA CCAACCCAGA AACCACCACC TCTCACGCCA AAGCTCACAC CTTCAGCCTC CAACATGAAG GTCTCCGCAG CACTTCTGTG GCTGCTGCTC ATAGCAGCTG CCTTCAGCCC CCAGGGGCTC GCTGGGCCAG GTAAGCCCCC CAACTCCTTA CAGGAAAGGT AAGGTAACCA CCTCCAGGCT ACTAGGTCAG CAAGAATCTT TACAGACTCA CTGCAAATTC TCCATTTGAA AAATAGGGAA ACAGGTTTTG TGGGTGGACA AGAAATGCCT CAACCGTCAC ATCCAGTCAC TGGAAGAGCC AGAACTAGAA AGCTCCCGAG TCTTTTCCCC ACATTCAAGA GGGCCGCTGG GTGCATCCTT ACCCAGCTAT CCTTACAGTG TTTGGGAATG GGGAATGGCT CTGTCTTACT GTGGGCATGG TGGGCATTTT TGGCAGTGGG AGAGAAGGAA

AATCTGTTGA TTAGAAGCTC AGTATGTTAA TTCGACTCCA GGACAGCTTT CAGAGACAGT GGCTAAGAGA AGAACGAGGT CCCAGGGGAT CTCTTGAGGT GACTTATTTT GACACTCTTT GGGAAAGTTA TCTAGGAGAT TTGTTCCATA ACTCATTTTC CCATACTCTG GTGACAAATT TACTGAGTGT ATCGGTCCCA CTGAGCCAGT GCATAGCATG GTAACAAACA GTTCTAAATT ATCAATGACT TAACAGAATT AACTAAATTA ACAAAAGTTA CTTTCTCACT TGTACTAAAT ATCTATAATG TATGGGCTCA GGCTTCTGCA TTTTATACTC AGGATTCTAG ACTGATGGAG AAGTTGCCAT GTGGGGGAAC ATTGATGGAT ACTGTGATAA AGCAGAAGAA AGCTCTCAGG AGTCTTGCAT AGGCAATGCA CTGTGGCTCA AAAATGACAC CCATCACTTT GTCTCCTTCT TTATTGATCA AAACTAATTA ATGCCTCCAA CCAAACAAAA GTGGCCAAGA AATGCAAGTC TACCTTGTGT

CTCAAAACAG AGGATGGAGA ATATTTGGTG AAAATTACCA TGACCATCAC ATGGCCACGT AGGTCTTTAT AATGACAGAG CTAGCATTTG TCACATTGAC CAAGCTTTGT CCATACACTC TACAGTAATG ATGAGTCCTC AGTGCACAGG GGAGGATGCT GAAGACACAG GACAGCATCC TCCAGACACA TAAGACTTCA GAGCAGAGGG ATTCTCCCTC CACCTCTCGC AATTCCTTGC TTTCTCCTAA CTTCCTTTAC AAAGTCATGC TTGGAAATGT CTATGTATCA TCATGTGGCT CATTTTTTTC TCTGTTCATT TTTTTTCCCC AAAATTCAGC TTCTGTCCCA ACCACCTGCT GCTTTAACCT GGCCAATAGG AAGATACCCC TTCAGCGACT AGAGAGCTAC AGGAGAATCA CCAGTGGCAA ATGTCCCCAG AAAGCTGTGA TGTAAGTAAA TAAAGTTCAC CCTCCCCTAG ACAAAAAAAT AATGTCTAGG GCACAGAGTC AAGAACTGTG GGAGTCATAG ACTCTGATAG TTTGACCTCT

ATGGTCCAAT TCATTAATTT TCACAAGTGA GTGTTCACTC CCAGCTCCCT GCCTGGGAGA TTGCTGTAGT CATATCAATT TCTTCAAGTC AAGAGCAAAG ATGGTTTTAC TGGGCCTTTA AGAGCAGCAA CTAACCCAAG AGTCTCATCC TTCCTCCTCT CCGTAGCAAC CCTTTGTCCA GGGGCAGATG GTCCTTAAAT ATTTAGGGTC AAATGGGCAG AATTTTCAAA AACAATCCTT CCAATTGCAT CCTGATTCTC CCCACAGCTT CAAGACCAAA CTGGCCAAGG ATATCTGTGC CGACCCCAAG AAGAAGTGGG TGCAGGATTC CATGAAGTAT CTGGACCAAA AATCTCCAAC TCCAAAGCCA TAAATAATCA CCATTTTTGA AACCAAACCA GAGCCTGAGT GTTGCCTAAT TTGTTTTCCC TTCTTACAAT GCATTCTGAG GTAACCTCAT TATCAGTCCA AAGGGCATGG GTTTTATTAT ATATATATAT ATATATTTTT TTTTAAAAAA AAACGTATTG CATTTAATTT ATTGAGGCTT TAAAACTTAT CCTCCATGAA TATCAGTTAT TTTTAAACTG TAAAGCTTTG TGCAGATTCT TTACCCCCTG GGAGCCCCAA TTCGATCCCC TGTCACGTGT GGGCAATGTT CCCCCTCTCC TCTCTTCCTC CCTGGAATCT TGTAAAGGTC CTGGCAAAGA TGATCAGTAT GAAAATGTCA TTGTTCTTGT GAACCCAAAG TGTGACTCAT TAAATGGAAG TAATGTTGTT TTAGGAATAC ATAAAGTATG TGCATATTTT ATTATAGTCA CTAGTTGTAA TTTTTTTGTG GGAAATCCAC ACTGAGCTGA GGGGG GCCAGGTCGC TGTTGGTCCA CGCCGCCCGT CGCGCCGCCC GCCCGCTCAG CGTCCGCCGC CGCCATGGGA GGCCGGAGCC GAGCCGGGGT CGGGCAGCAG CAGGGACCCC

CCAGAGGCGG GGCCTGTGGG ACCGCTATGG GCGTGGAGAT CGAGACCATC TCCCCCGGAG ACGGAAGGAC ATTCCCCAAG AAGGGCCAAA CGTGTGTGGT GCACTACACA GGAATGCTCC AAAATGGGAA GAAGTTTGAT TCATCCAGAG ACAGAAACAA ACCTTTCAAG TTCAGAATTG GCAAACAGGA AGTCATCAAA GGTTTTGAAG AGGGTGCAGC CCAGATGAGC TTGGGGCAGA GGGCGAAGCT GACCTGCACC CCTGATGTGG CATATGGAGC CACGGGCCAC CCCGGTGTCA TCCCTCCCAA TGCCACCCTC ATCTTTGACG TGGAGCTGCT CAACTTAGAG TGAAGGCAGG AAGGAACTCA AGGTGGCTGG AGATGGCTGC TGCTCACCCT CCTAGCCTGC TCTGCCACTG GGACGGCTCC TGCTTTTGGG GCTCTTGATC AGTGTGCTAA CCTCACTGCC TCATGGCATC ATCCATTCTC TCTGCCCAAG TTGCTCTGTA TGTGTTCGTC AGTGTTCATG CGAATTCTTG

CTTGAGGAAA CTTCGGTTGC AGATTGAAGC ATTTCAGGTT GTGCATTTTG TGTGATGCAT GTAGTAGCCT TTCCTGATGA CAGAACACAG ATCTCTTGTT CGCACAATCT ACACTGCCTT ACCTTCACTT AAACCACACA CACAAGGTGC TCAGACATGA AATGTACATG GCGTACCGTA CACAGAGGGA CTTGAGCCAG TTACCTTTGC TGTCACTTTC TCTCTTATAA ATTCTGTTAG CTGCTCACTT AAACAATGTC CTCTTTGAGA AAATGTAAAA TAAAGGCTCT GTGCTTGACA GAATTCGGGC CGCCGCCAGG TCGCTGTTGG TCCACGCCGC CCGTCGCGCC GCCCGCCCGC TCAGCGTCCG CCGCCGCCAT GGGAGTGCAG GTGGAAACCA TCTCCCCAGG AGACGGGCGC ACCTTCCCCA AGCGCGGCCA GACCTGCGTG GTGCACTACA CCGGGATGCT TGAAGATGGA AAGAAATTTG ATTCCTCCCG GGACAGAAAC AAGCCCTTTA AGTTTATGCT AGGCAAGCAG GAGGTGATCC

GAGGCTGGGA AGAAGGGGTT GCCCAGATGA GTGTGGGTCA GAGAGCCAAA CTGACTATAT CTCCAGATTA TGCCTATGGT GCCACTGGGC ACCCAGGCAT CATCCCACCA CATGCCACTC TCGTCTTCGA TGTGGAGCTT CTAAAACTGG AATGACAGGA ATGGCCTCCT CCCTTAGCTC CCTGTTCTTG GATCTGCCAT GGAGGGATCT GGTGCCTCCA GACATGTGCA CATGAGTCCA TATGGAGCTT TTCCTGATGT TCCACTCCAC TTTGTATAGA CATCTGCCCT GACTGAATGT GTTCTGTCAC TCAGCTTTGC TTCCGACACC TCTGTTTCCT CTTCCCCTTT CTCCTCGTAT GTGTGTTTAC CTAAACTATA TGCCATAAAC CTCAAGTTAT TCATTTTATT TTGTTTTCAT TTTGGGGTGA AGATTCAGTT TCAGTCTTTT GGATATAGGT TTCCAATTAA GTACATGGTC AAGTATTAAC AGCACAAGTG GTAGGTTAAC ATTAGAATAG GAATTGGTGT TGGGGGGGGG GTTTGCAAGA

ATATTTTATT TTAATTTTTT GGATGAAATT TTTATCTATT ATATATTAAA CATTCTTGCT GCTGCGCTGC AAAGCCATAG CAGATTTGAG GCGCTGTTGA GGACTGAATT ACTCTCCAAG TTGAGAGATG TCTTTGGGTT AAATTAAAAG CCCTACCTAA AACTGAGGTG GGGATGGGGA GAGCCTTTGC CTCCACCATT CCCACCCACC CTCCCCTTAA ACCCTCTGCC TTTGAAAGTA GATCATGTTC ACTGCAATGC TGGACACTAC AGGTATCTGT CCCTGGGCCA GCAGGGACCT CTGAAGCCTT CTTTGTGGCC x x x TTCATCCTGT GGTTTTTCTA ATGGACTTTC AGGAATTTTG TAATCTCATA ACTTTCCAAG CTCCACCACT TCCTAAATCT TAAGAACTTT AATTGACAGT TTCAATTGAA GGTGCTGTTT GTAGACTTAA CACCCAGTGA AAGCCCAGCC ATCATGACAA ATCCTTGAAT GTTCTCTTAA GAAAATGATG CTGGTCATCG CAGCTTCAGC ATCTCCTGTT

TTTTGATGCT TGGCTCCCTC TGCTGATCTC AGTTTCCTGG CTTTTCCTCC CTCAGCCCCT TCTCACCCCT TTGCTGTCCT GTGTAGTGAT TTGGTGAGAA ATCGTTGCTG CACCCTTCCC CCAGCACCAT TTATGAGTCT CAAGTTTTAT TATTGCAATA AAAGTGCTTT ATGCCCGAAT TC GCCGCCGCCA TGGGAGTGCA GGTGGAAACC ATCTCCCCAG GAGACGGGCG CACCTTCCCC AAGCGCGGCC AGACCTGCGT GGTGCACTAC ACCGGGATGC TTGAAGATGG AAAGAAATTT GATTCCTCCC GGGACAGAAA CAAGCCCTTT AAGTTTATGC TAGGCAAGCA GGAGGTGATC CGAGGCTGGG AAGAAGGGGT TGCCCAGATG AGTGTGGGTC AGAGAGCCAA ACTGACTATA TCTCCAGATT ATGCCTATGG TGCCACTGGG CACCCAGGCA TCATCCCACC ACATGCCACT CTCGTCTTCG ATGTGGAGCT TCTAAAACTG GAATGACAGG AATGGCCTCC TCCCTTAGCT

CCCTGTTCTT GGATCTGCCR TGGAGGGATC TGGTGCCTCC AGACATGTGC ACATGARTCC ATATGGAGCT TTTCCTGATG TTCCACTCCA CTTTGTATAG ACATCTGCCC TGACTGAATG TGTTCTGTCA CTCAGCTTTG CTTCCGACAC CTCTGTTTCC TCTTCCCCTT TCTCCTCGTA TGTGTGTTTA CCTAAACTAT ATGCCATAAA CCTCAAGTTA TTCA AAGCTTCTAC CCTAGTCTGG TGCTACACTT ACATTGCTTA CATCCAAGTG TGGTTATTTC TGTGGCTCCT GTTATAACTA TTATAGCACC AGGTCTATGA CCAGGAGAAT TAGACTGGCA TTAAATCAGA ATAAGAGATT TTGCACCTGC AATAGACCTT ATGACACCTA ACCAACCCCA TTATTTACAA TTAAACAGGA ACAGAGGGAA TACTTTATCC AACTCACACA AGCTGTTTTC CTCCCAGATC CATGCTTTTT TGCGTTTATT ATTTTTTAGA GATGGGGGCT TCACT ATGTT GCCCACACTG GACTAAAACT

CTGGGCCTCA AGTGATTGTC CTGCCTCAGC CTCCTGAATA GCTGGGACTA CAGGGGCATG CCATCACACC TAGTTCATTT CCTCTATTTA AAATATACAT GGCTTAAACT CCAACTGGGA ACCCAAAACA TTCATTTGCT AAGAGTCTGG TGTTCTACCA CCTGAACTAG GCTGGCCACA GGAATTATAA AAGCTGAGAA ATTCTTTAAT AATAGTAACC AGGCAACATC ATTGAAGGCT CATATGTAAA AATCCATGCC TTCCTTTCTC CCAATCTCCA TTCCCAAACT TAGCCACTGG TTCTGGCTGA GGCCTTACGC ATACCTCCCG GGGCTTGCAC ACACCTTCTT CTACAGAAGA CACACCTTGG GCATATCCTA CAGAAGACCA GGCTTCTCTC TGGTCCTTGG TAGAGGGCTA CTTTACTGTA ACAGGGCCAG GGTGGAGAGT TCTCTCCTGA AGCTCCATCC CCTCTATAGG AAATGTGTTG ACAATATTCA GAAGAGTAAG AGGATCAAGA CTTCTTTGTG CTCAAATACC ACTGTTCTCT

TCTCTACCCT GCCCTAACCA GGAGCTTGTC ACCCCAAACT CTGAGGTGAT TTATGCCTTA ATCAAGCAAA CTTCCCTCTT CAGAAAAGAT GGCTCATTTT CCCTCAAAAG TTGCCAGGAG CTGCCAAGTA TTCTGCCAAT TCACCCTGGA GCACAATCAA CAAATTCAGC CAGAACACAA CTACAGCTAC TATTAGAACT ATTATTATTA ATAAATTCCT CTCCAAATCT AGCCCCTTGA CTTCGGATTT CACGATTTCT CCCTTCCTCC TAGAAACTTG ATAAGTTTCC CGCGCTTCCC TTTTTCTAAG ACTACATGTT TGTCATCTTA TAAAGCAAAG GGGTGAATAA ATGAACCAAA TCAATAACTT CTGGAATATC TGCAAACAAC AATAATATCA GCTATGCCAT CTTTCACTAT TTTAGCCAGT ATCGAGTTGA ATGAACATAG AAAAATAGAA AACTGAATTC TTCCCTGTAA ATTCCCCGTT TTGACGACGC ACTTGTAGCC ACGTAGCCAC GCCTACTTAA GACAATTACA AAAGGCGAAG

AAGACTGACT CAGGCTTAAG CTGCCAGCCA GAGAGGGAGT CATTTCATTG GCGTTTGAGT CAGCAAAGGT ATTGTCCTCA CATCTCTGGC TATTAAAGTA TTTTCTGTTG TTGTTTTTCT CTTTGGCTGT TTTCTCTCAC ATTGCCTTCT CTAAAGCTAC AGTCTCTCCT TTCTTTTCTT GTCCCTCCCT GGTTTGGTAT GTGACCTAGA ATTACAGTCA GATTTCAGAA AATGATTCTC TCATTTTGCT GATAAGGACT GATTCGTTTT ACTGAGGGAC GGCAGAACTA GTTTCCTATG AGGGCATGGG TGAATACAAC TGAGGCTTCT CATGGGAGGG AATCTCTACT ATCCAAAATT ATTAGGAGAA AATTGAAAAT TTCCAACTCT GTCTCTCTCT TACCTCTGTG TAAGGCAAAT ACCTTATTCT TGTGGTGTTT TTGTAACCTC TTCAAACTTT CATTGATTGA ATGCCTGTTC TGGCAATACA TTAGGTTGGG CACATAAGGA ATACCAACAT AAATAAAACA TTCTAAAAGA AGTTTACGAT

CTAATAAAGG AGACAGGTAC ATAGCAAACT AATTCAAAGG AGCTAGAAGA TGGAGAAAAT GCTGAATGTG GACTAAGTCA TTCAACAAAG TTTTCAGGAA GCACAAAGAG GAGGGGCTCC CCTCACAGAT ATCTGGATTA GAGGCTGGCT GAGCTGATGG TGGCTGGTGT TCTCTGTTGC AGAAGTCAAG ATGGCCAAAG TTCCAGACAT GTTTGAAGAC CTGAAGAACT GTTACAGGTA AGGAATAAGA TTTATCTCTT GTGATTTAAT GAGGGTTTCA AGGCTCACCA GAATCCAGCT AGGCATAACA GTGGCCAGCA TGGGGGCAGG CCGGCAGAGG TTGTAGAGAT GTGTACTAGT CCTGAAGTCA GAGCAGGTTC AGAGAAGACC CAGAAAAACT AAGCATTCAG CATGTTAAAC TGAGATTACA TTGGCAGGGA GACCGCCATT TTAGAAAAAT TATTTTTGAG GTCTGCTGAG CCCTACATGA ATATCAGCAT CAACTTAGAC ACAGCCTCTG TTGAGATCAC

ATGCCCTGAT ATAAGAATGG GTTTTACTGG TCCATTCTCA GGAAAACTTG ATCTCATTCA GGAACAGGAA ATGGCTCCAC AGCAAGCTGG GCATGTGAAC TCACATATGC AGGCAAATCT CACTCAGATG TAGAAGAAAG GTAAATGAAC ACAAAGATAA AATTACGGAA CATATTAAAC TAACATGATG TTTCCATTAT CTGTAGTAAA TACTAACACA AACTAGGCTG TCAAAATTTT GCCTGGATAT TTTACTAAGT ATAAATTATG AAATCTGTTT TAGTGAATAC ATGAAAGTAA TGTGTAACAT ATAATCTATT TGGTTAAAAT AAAAAGGAAG TGCTTCAAAA CCTTTCTTTT CTCTAAAGGA GCTTAACATT CTTCCCTGAA CTTCAATTAA AGCTCTTCAA TTTGTTAGCC AAGTCCAATT TTTACAGATA AAGCACAGGT AAAGCTCAAA GCCTGTCTTG ATGACTACTA ATTCCAGATT AGTAAGATAT GAATTACTCT ACCTATGTGT ATGTGTAGAA GTCCTTAAAT TTCAAAGATG

ACAGTAATGG CCATGTGTAT GTGTGTGACC CACAACTATC ATGGTCATTA AAGTACATTG GCCAGAGACC ACATGAAATA ACAACAATTA CATTCTCATC ATCTTATTTT GACAGTGAAA ATGAAGAAGA CAGTTCCTCC ATTGATCATC TGTCTCTGAA TCAGGTAAGC AAATGACTGT AATTCTCATG GGACTGCTAT TCTTACACAG TGGTTTCTTC ATCCAAAGAG AACAGCAATG ACTTGAATCT TAAATACTTT TGTTTTACCC TCACTAGAGA TCCAGAGACC TGTCTTTCAT TATAAGTGAG ACCAGCTGCC TCTCTAAACT AATAGTTGAT GTGCATTGGC TTCTCCCAGA ACAGAGCAGA ACTATCCCAA ATCCCTGAGA ACTGGAGTCT CCTGGGGCAG GCTTCATCAG GATGTTAGTT ATGCCATCCT GAGAAAGCCC CGCAGGCCGC TTCACCAGGT GTCTGTCTCC TAACGTGATG TGTTGTGGTT GTCTTCTCTG ACACCAGCAT CAGAGGTTAG AGAAAGTCTC CAAACATGAA

GCTGAGAGAG AGGAAGCAAG CCAGCTGAAA GTGAGAAGTC TACAGCCACT CATCAATCTG TGTTATTGTG TTTGGAGACC ACAAATAGAC ACTATAAGTA CTGCCTAGTA TGTCTTCAGT ACTGGCTTTA AAAGCTGTCC CCAAAGGAGT ATTTCTAAAA TATTTTGAGC ATTGTTAAGC AGATTTTTAA CCTCCTGAGA GGGAACTAAT TGGAAAGCTA CCACTCACTA CAATCATTGT TAACCTATTT AGTTACAACA TCTCATTTTT GAGCATGCAA ATAAATGAAA AAGTCTTCCT AAAAAAATCA TCTTTTTATC CTGGAAGGAG GAAGGAAGGT GAGACAAAAG GGAGAGAGGG AGGGAAGCCT AATGAAACAC CAGTTACCTA AGACCAGAAT GGAGATCCTC CTCACTACCT CTGTTGAATA CAGCACCTAC TGAAAGAACT TTCATTCCCT GACCATGAAC AGCCTCTCAG CTTCTGTTTT CCTTCCTCAC AGAAATCCTT CTATCATGTA AGCTATGGCC CACTCCATGA

AGGCTGCATG GATCAATCTG TGTCTCTGAG TATCTCTGAA ACCTCTAAAA CATCCAAGCT TACCTTCAAG GAGAGCATGG TGGTAGTAGC AACCAACGGG AAGGTTCTGA AGAAGAGACG GTTGAGTTTA AGCCAATCCA TCACTGATGA TGACCTGGAG GCCATCGCCA ATGACTCAGA GGAAGGTAAG GGGTCAAGCA CAATAATATC TTTCTTTTAC AGTTTTAAGC AAGTAGGGAC AGTAGAATTT AGGGGAAAAT TAAACGTGGA GTCAGAATAA CAAGAAGACA ACCAAGCATT AGTCTGGTAA CTATACAGAG GAAAATTAAT TTTTATCCTT CTCCAGGAGG GAGAAATGAG CAGTGGCCTG AATCGAGAAT ACTTGCTCAC AGCCATTATT TCTTAGCCAT ATTGTAAAGG TCGTGTGACT TTTAGCCTTT CAGGAGAAAG CAGTAATAAG ACCACTTACG AGCTATGTTC CTCTCATACT AACTATGCCT CCTTGGTCAT GTTACATAAT CTTTTCGTGA TTCAGTTTCC

TCTACTGTAA AATGGAGATA ATCAGAATCC CCCACTCATT GGATTGTTGT AAAGATTAAG AGTCTCAGGC TTTACAGACT GAGCTAGCTG GGCCCTCCTG ACTGTTATAA AGATTAAATG AGTCAACATC CCCTAACTTC TGGACTAGAA TAATGTCTGG TACAAAGTAA GCACCCAATA AATGTTAGCT ATTACTATCA TTATTATTAT TATTTTATTT TTTTTTTTTG AGATGGAGTC TGGCTCTGTC ACCCAGGCTG GAGTGCAGTG GCACAATCTC GGCTCACTGC AAGCTCTGCC TCCTGGGTTC ATGCCATTCT CCTGCCTCAG CCTCCCGAGT AAGCTGGGAA TACAGGCACC CGCCACTGTT CCCGGCTAAT TTTTTGTATT TTTAGTAGAG ACGGAGTTTC ACCGTGGTCT CCATCTCCTC GTGATCCACC CACCTTGGCC TCCCAAAGTG CCGGGATTAC AGGCGTGAGC CACCGCGCCC GGCCTATTAT TATTATTATT ACTACTACTA CTACCTATAT GAATACTACC AGCAATACTA

ATTTATTAAT GACTGGATTA TGTCTAAACC TCACAAGAAT CCTACCTTCT CATTTTACAT AAAAGGAAAC TAAGCTCATT GAGATAGGTA AACTGCCCAA TGGCATACAT CTGTAAGTGG GAGAGCCTCA AATCTAATTC AGTTCTACCT GAGTAAAAAA ATCATGGTTT CTCCTCCATC CCTTTACTGT ACAAGCCTCC ACATGAACTA TAAACCCAAT ATTCCTGTTT TTAAGATAAT ACCTAAGCAA TAACGCATGT TCACCTAGAA GGTTTTAAAA TGTAACAAAA TATAAGAAAA TAAAAATCAC TCATATCGTC AGTGAGAGTT TACTACTGCC AGCACTATGG TATGTTTCCT TAAAATCTTT GCTATACACA TACCTACATG TGAACAAATA TGTCTAACAT CAAGACCACA CTATTTACAA CTTTATATCC AGCTTTTCTT ACTTAGCAAT GTATTGAGGA CATTTTAGAG TGCCCGTTTT TCACCATTAT AAGCAATGCA ACAATGAACA TCTGTATAAA TAAATATTCA TTTCTCTCAC

CCTTTATTTC CTTAGAATAT ATTCCTAGAA GTAGAATTTC CCAGAGCCAT GAGGATTTGT GACGCTATTG ATATGTGCCA CTTTGCACTC TCTGTGACAT ATATAATTAT TTTTAATGCA TTCATTTTTT TCTCAGAGTG CATTCGTTTG AAAACATAGA CGGGAAATAC TGGTAGTCTT CCTTGTCAGT TAGAAACACC CAAACAATGA AAAATGAAAA AGTTGCACAA ATAGTCTCTA AAAACAATGA AACTATTGCC TGAGGAATTG AAGTTTAAAA AGAAGCACAT AAGCAACAAC AAGGATAATC CTAGAAAACC AGTTCTGCTG ACTGGGTGAT TTCACTTCTC TTTGCTTCCT CATCTGGATT GGAATATTCC TAATACCCCC TCCAGAACTA TTTTCCCTGT TTGTACTAGA CTGTGTATAT CATCTGTGTT TGTACATAGA CATTAATCTG CACTTGTGAT CATGGTTTTA GAAATCATCA AGCCTAGGTC ATCACCTTTT AGCTTCCTGA GCAATGTGAA ATACAACTTT ATGAGGATCA

TCAAATACGA ATTCATCCTG AATGACGCCC TCAATCAAAG TATAATTCGA GCCAATGATC AGTACCTCAC GGCTGCTGCA TTACATAATC TGGATGAAGC AGGTACATTA

AAATGGCACC AGACATTTCT GTCATCCTCC CCTCCTTTCA TTTACTTATT TATTTATTTC AATCTTTCTG CTTGCAAAAA ACATACCTCT TCAGAGTTCT GGGTTGCACA ATTCTTCCAG AATAGCTTGA AGCACAGCAC CCCCATAAAA ATCCCAAGCC AGGGCAGAAG GTTCAACTAA ATCTGGAAGT TCCACAAGAG AGAAGTTTCC TATCTTTGAG AGTAAAGGGT TGTGCACAAA GCTAGCTGAT GTACTACCTC TTTGGTTCTT TCAGACATTC TTACCCTCAA TTTTAAAACT GAGGAAACTG TCAGACATAT TAAATGATTT ACTCAGATTT ACCCAGAAGC CAATGAAGAA CAATCACTCT CCTTTAAAAA GTCTGTTGAT CAAACTCACA AGTAACACCA AACCAGGAAG ATCTTTATTA TCTCTGATAA

CATATTTGTG AGGCAAAACC TCCAATAAGC TACAAATATG GCTTAAAGGA TGAAGTTTAG TGTCCAAAAA CTTTTATCAC ACACATCCAA TTTTCATGGC GGACATGTTT TAGTTTCAAC AGTATACATA TTTTCAAAGG TCCAGAGAGG CAATTTTGCA ATAAACAAGC AAGACTTTTT CTGATTGGAT GCACTTCAGC TAACATGCTT TCAACTCTAC ATTTACAAAT TATTTTGTGT TCTATTTTTC TACTTAATAT TATTTCTGCA ATTTTCCCAA TATTGACATC GTGTATGTAT TTGCCATTTT TAATATCACT AGACAATTCA ATCAGGTTGC TACGTTGGTC CCTTGGGTTT ACTCTAAATA GCTTGATTGC AAATATCTTT GTATATATTA TTGTTTTTTC TCCTATCTTG TAATTTCTTT GAGCACATCC CAAAGAGGAA TGCCTAGATC AATGGGCACA AATAATTTGA CAGCTCTTAT TAAAGATTAT TCTGTAAGTA AAAACTGAAC TACTTTTCAG TATCACTAGC AACATATGAG TGTATCAGCT TCCTAAACCC CTCCATGTTA GGTCATTATG AACTTATGAT CTAACAAATT ACAGGGTCTT ATCCCACTAA TGAAATTATA AGAGATTCAA CACTTATTCA GCCCCGAAGG ATTCATTCAA CGTAGAAAAT TCTAAGAACA TTAACCAAGT ATTTACCTGC CTAGTGAGTG TGGAAGACAT TGTGAAGGAC ACAAAGATGT ATAGAATTCC ATTCCTGACT TCCAGGTATT TACACCATAG GTGGGGACCT AACTACACAC ACACACACAC ACACACACAC ACACACACAC ACCATGCACA CACAATCTAC ATCAACACTT GATTTTATAC AAATACAATG AATTTACTTT CTTTTTGGTT CTTCTCTTCA CCAGTGAAAT TTGACATGGG TGCTTATAAG TCATCAAAGG ATGATGCTAA AATTACCGTG

ATTCTAAGAA TCTCAAAAAC TCAATTGTAT GTGACTGCCC AAGATGAAGA CCAACCAGTG CTGCTGAAGG TCAGTTGTCC TTTGTCTCCA ACTTACCTTC ATTTACATCT CATATGTTTG TAAATAAGCC CAATAGGCAG ACACCTCTAA CAAGGTGACA CTGTCCTCTT TCCTTCCTAC CACAGCCCCC ACCTACCCAC CCCACTCCCA TTGATTCCAG AGGCGTGCCT AGGCAGGATC TATGAGAAAA TATAACAGAG AGTAAGAGGA AAATTACCTT CTTTCTTTTT CCTTTCCCTG CCTGACCTTA TTCACCTCCC ATCCCAGAGC ATCCATTTAT TCCATTGATC TTTACTGACA TCTATTATCT GACCTACACA ATACTAGACA TTAGGACAAT GTGGCCTGCC TCCAAGAAAC TCAAATAAGC CAACTGAGAT CAGAGAGGAT TAATCACCTG CCAATGGGCA CAAAGCAACA AGCTGGGAGC CAAGTCCCAA AATGGGGCCT GCTGCTTCCA GTTCCCCTCT CTCTGCATTG ATGTCAGCAT

TATCCTTCGT CCCAGTCCTG TCTCCACTAC CACTTTCCCC CTCAAACACA CACACACACA ACAGCCTTAG ATGTTTTCTC CACTGATAAG TAGGTGACTC AATTTGTAAG TATATAATCC AAGACCTTCT ATTCCCAAGT AGAATTTATG TGCCTGCCTG TGCTTTTCTA CCTGGATCAA GTGATGTCTA CAGAGTAGGG CAGTAGCTTC ATTCATGAAC TCATTCAACA AGCATTATTC ACTGAGAGCC TTGTATTTTT CAGGCATAGT GCCAACAGCA GTGTGGACAG TGGTGCATCA AAGCCTCTAG TCTCATAGAA CTTAGTCTTC TGGAGGATAT GGAAAACAGA CAACCCAAAC AACCAACAAA AGAGCAAGAT GCTGCAAAAA AAAAAAAAAT GAATAGGGTG CTAAGATAGA GAAAAGTGGG AGAGTGCTAT TTAGACAAAG TGGTAAAAAC AAAGCCCCTT GTGAGATGAG AGCTGCCGAC AGAGGGGGCG GGTCATGGTT GTGGGTTTTT GGGTAGGACA

TTCAGAGGAG GGGGCGGGTC GTGGTTGTGG GTTTTTGGGT AGGACATTCA GAGGAGGGGG CGGGTCGTGG TTGTGGGTTT TTGGGTAGGA CATTCAGAGG AGGGGGCGGG TCGTGGTTGT GGGTTTTTGG GTAGGACATT CAGAGGAGGG GGCGGGTCGT GGTTGTGGGT TTTTGGGACA TTCAGAGGAG TCTGAATGCA CCCAGGCCTA CAACTTCAAG. ATGGTAAAGG ACAGCTCCAA GGATCAGAAG AAGCATTCTT GGAACTGGGG CATTTTGAGA AGGAGGAAAA ATATGCAGAG ACTAGTGCTT GCAGAGCTTG CATTTGGATT TCATTTGAGG TACAATGAAA ACCCATTAAT GGGTTTCACA CAGTGCAATG GCCTGACCTC ACTTATATTT CCTAAAATAG AAAACAGATC AGAAGGAAGG CAATAGAGAA GCAGAAAGTC CAATGAGGAG GTTTCACAGC AGTCATGGGG GTGGGGTAAG GAAAAGAAGT GGAAAGAAAC AGACAGAATT

GGGTTATATT TTGGAGATAG AACCAACAGA AGGAAGAGGA GAAACAACAT TTACTGAGAA GGGAAAAAGT AGGAGAGGAA TAGGTTTGGG AAATAAATCC TGCTGACATT GGAAACCCCA AGGAAGCCTC AAAAGTATAT TTACTTGCTT TAGATTTAAA AGAATAGGAA AGAAGCATCT CAACTTGGAA TTTGAAATCT ATTTTTCCAT AAAAGTATTG TTAAATTCTA CTCATACTCA CAAGAAAAGT ACATTCTAAA GAGTATATTG AAAGAGTTTA CTGATATACT TAGGAATTTT GTGTGTATGT GTGTGTGTGT ATGTGTGTGT GTGTGTTTAA CCTTCAATTG TTGACTTAAA TACTGAGATA AATGTCATCT AAATGCTAAA TTGATTTCCC AAAGGTATGA TTTGTTCACT TGGAGATCAA AATGTTTAGG GGGCTTAGAA TCACTGTAGT GCTCAGATTT GATGCAAAAT GTCTTAGGCC TATGTTGAAG GCAGGACAGA AACAATGTTT CCCTCCTACC TGCCTGGATA

CAGTAAGATA CTAGTGTCAC TGACAATCTT CATAACTAAT TTAGATCTCT CTCCAATCAA CTAAGGAAAT CAACTCTTAT TAATAGACTG GGCCACACAT CTACTAGGCA TGTAATAAAT GCTTGCTGAA TGAACAAATG AATGAAGAGC CTATAGCATC ATGTTACAGC CATAGTCCTA AAGTGGTGTT TCTCATGAAG GCCAAATGCT AAGGGATTGA GCTTCAGTCC TTTTTCTAAC ATCTTGTTCT CTAACAGAAT TCTCTTCTTT TCTTCATAGG AGATGCCTGA GATACCCAAA ACCATCACAG GTAGTGAGAC CAACCTCCTC TTCTTCTGGG AAACTCACGG CACTAAGAAC TATTTCACAT CAGTTGCCCA TCCAAACTTG TTTATTGCCA CAAAGCAAGA CTACTGGGTG TGCTTGGCAG GGGGGCCACC CTCTATCACT GACTTTCAGA TACTGGAAAA CCAGGCGTAG GTCTGGAGTC TCACTTGTCT CACTTGTGCA GTGTTGACAG TTCATATGTA CCATGTACAT GAAGAAGCTA

AATCCTTTAC TGTTAGTCAT TTGCTGAGCA TGTACTGAGC CTTGTAATTC TAAATGAATG TTTACACTCT TTGTAAGAGT GGAACCAACA CTAACATATA ATGTTGTTAT TTAAAGAACA CCCTATATTT TGCATAGTAC CAATCATTTT AATTATTATT CTTCATAACA ATTTTAGGAG GACCAGAGCT ACTGACTATG GCTACCAAAA AGACTCTACC CATATTACAG ATGGGCAAAT TAAGGCATAA GAAAACTAAG AAATATGCAC AATAGCAGTT GAAACAAGAA GCCACAGACC TAGGATTTCA TGATTTCATT TCAACTGTTT GCCTTCTGCT TTTAAGTTGC TGATGAACTC TTAATCAAAT AGCATAAGTT TCTGGGACCT CAGTTTTATC ATTTTCAAAA TGGAGGGAAT AATACCTAAG CCTTCCTGCC GCAACAGTTT TTTATGCTAA TCAGGGAGGT CATTTTGGTA AAATACTTCT CGAAGCCGAG CCTCAAGATG AAGGCAAAGC ACGAAATGTT ATTTTTTAAT TATTATTTAT

ATATGTATTT ATAAATATAT TTAAGATAAT TATAATATAC TATATTTATG GGAACCCCTT CATCCTCTGA GTGTGACCAG GCATCCTCCA CAATAGCAGA CAGTGTTTTC TGGGATAAGT AAGTTTGATT TCATTAATAC AGGGCATTTT GGTCCAAGTT GTGCTTATCC CATAGCCAGG AAACTCTGCA TTCTAGTACT TGGGAGACCT GTAATCATAT AATAAATGTA CATTAATTAC CTTGAGCCAG TAATTGGTCC GATCTTTGAC TCTTTTGCCA TTAAACTTAC CTGGGCATTC TTGTTTCATT CAATTCCACC TGCAATCAAG TCCTACAAGC TAAAATTAGA TGAACTCAAC TTTGACAACC ATGAGACCAC TGTTATCAAA ACTTTCTTTT CTGGAATGTA ATCAATGTTT CTTCTAGGTT CTAAAAATTG TGATCAGACC ATAATGTTAC ATTATTATCA ACAATAGTGA TTGATAGAGT GTTATCAGTC ATAACTAAAT AAAGCTTGCA ACAAAATTCT CTGACACATA GTTATTCATT

GCCTTAATCA TTATTTTACT GCATGGTAAT TAGGGACAAA TGGTAAATGT TTACATAAAT AATTGTATTT AGTGTTACTT TATAAAATCA AACCAAGATT TTATATTTTT TTCTCCTCTT TGTTAGCTGC CAGTATGCAT AAATGGCATT AAGAATGATA ATATTTCCGG GTTCACTTAA AGCTCATATT ACACATACAC AAAACATGTG TTCCCATCTT TATACAAACT CACACATACA GAGCTACATT AAAAACAACT AATAGGCCAG GCACGGTGGC TCAGACCTGT AATCCCAGCA CTTTGGGAGG ACCAACCTCT

TCGAGGCACA AGGCACAACA GGCTGCTCTG GGATTCTCTT CAGCCAATCT TCATTGCTCA AGTGTCTGAA GCAGCCATGG CAGAAGTACC TGAGCTCGCC AGTGAAATGA TGGCTTATTA CAGTGGCAAT GAGGATGACT TGTTCTTTGA AGCTGATGGC CCTAAACAGA TGAAGTGCTC CTTCCAGGAC CTGGACCTCT GCCCTCTGGA TGGCGGCATC

CAGCTACGAA TCTCCGACCA CCACTACAGC AAGGGCTTCA GGCAGGCCGC GTCAGTTGTT GTGGCCATGG ACAAGCTGAG GAAGATGCTG GTTCCCTGCC CACAGACCTT CCAGGAGAAT GACCTGAGCA CCTTCTTTCC CTTCATCTTT GAAGAAGAAC CTATCTTCTT CGACACATGG GATAACGAGG CTTATGTGCA CGATGCACCT GTACGATCAC TGAACTGCAC GCTCCGGGAC TCACAGCAAA AAAGCTTGGT GATGTCTGGT CCATATGAAC TGAAAGCTCT CCACCTCCAG GGACAGGATA TGGAGCAACA AGTGGTGTTC TCCATGTCCT TTGTACAAGG AGAAGAAAGT AATGACAAAA TACCTGTGGC CTTGGGCCTC AAGGAAAAGA ATCTGTACCT GTCCTGCGTG TTGAAAGATG ATAAGCCCAC TCTACAGCTG GAGAGTGTAG ATCCCAAAAA TTACCCAAAG AAGAAGATGG AAAAGCGATT TGTCTTCAAC AAGATAGAAA TCAATAACAA GCTGGAATTT GAGTCTGCCC

AGTTCCCCAA CTGGTACATC AGCACCTCTC AAGCAGAAAA CATGCCCGTC TTCCTGGGAG GGACCAAAGG CGGCCAGGAT ATAACTGACT TCACCATGCA ATTTGTGTCT TCCTAAAGAG AGCTGTACCC AGAGAGTCCT GTGCTGAATG TGGACTCAAT CCCTAGGGCT GGCAGAAAGG GAACAGAAAG GTTTTTGAGT ACGGCTATAG CCTGGACTTT CCTGTTGTCT ACACCAATGC CCAACTGCCT GCCTTAGGGT AGTGCTAAGA GGATCTCCTG TCCATCAGCC AGGACAGTCA GCTCTCTCCT TTCAGGGCCA ATCCCCAGCC CTTTTGTTGA GCCAGGCCTC TCTCACCTCT CCTACTCACT TAAAGCCCGC CTGACAGAAA CCACGGCCAC ATTTGGTTCT AAGAAACCCT CTGTCATTCG CTCCCACATT CTGATGAGCA ACCGCTTCCC TATTTATTTA TTTATTTGTT TGTTTGTTTT ATTCATTGGT CTAATTTATT CAAAGGGGGC AAGAAGTAGC AGTGTCTGTA AAAGAGCCTA

GTTTTTAATA GCTATGGAAT CAATTCAATT TGGACTGGTG TGCTCTCTTT AAATCAAGTC CTTTAATTAA GACTGAAAAT ATATAAGCTC AGATTATTTA AATGGGAATA TTTATAAATG AGCAAATATC ATACTGTTCA ATGGTTCTGA AATAAACTTC TCTGAAG AGAAAGAAAG AGAGAGAGAA AGAAAAGAAA GAGGAAGGAA GGAAGGAAGG AAGAAAGACA GGCTCTGAGG AAGGTGGCAG TTCCTACAAC GGGAGAACCA GTGGTTAATT TGCAAAGTGG ATCCTGTGGA GGCANNCAGA GGAGTCCCCT AGGCCACCCA GACAGGGCTT TTAGCTATCT GCAGGCCAGA CACCAAATTT CAGGAGGGCT CAGTGTTAGG AATGGATTAT GGCTTATCAA ATTCACAGGA AACTAACATG TTGAACAGCT TTTAGATTTC CTGTGGAAAA TATAACTTAC TAAAGATGGA GTTCTTGTGA CTGACTCCTG ATATCAAGAT ACTGGGAGCC AAATTAAAAA TCAGAAGGCT

GCTTGGAGAG CAAGTCCATG AAATGCTCTT TTTCCCACAG TAGAACCTAT TTCCCTCGTG TCTCAAATAC TTGCACAGAG GCTCACTCCC TTGGATAATG CAGAGCGAGC ACGATACCTG GCACATACTA ATTTGAATAA AATGCTGTCA AATTCCCATT CACCCATTCA AGCAGCAAAC TCTATCTCAG CTGAATGTAC ATGCCAGGCA CTGTGCTAGA CTTGGCTCAA AAAGATTTCA GTTTCCTGGA GGAACCAGGA GGGCAAGGTT TCAACTCAGT GCTATAAGAA GTGTTACAGG CTGGACACGG TGGCTCACGC CTGTAATCCC AACATTTGGG AGGCCGAGGC GGGCAGATCA CAAGGTCAGG AGATCGAGAC CATCCTGGCT AACATGGTGA AACCCTGTCT CTACTAAAAA TACAAAAAAT TAGCCGGGCG TTGGCGGCAG GTGCCTGTAG TCCCAGCTGC TGGGGAGGCT GAGGCAGGAG AATGGTGTGA ACCCGGGAGG CGGAACTTGC AGGGGGCCGA

GATCGTGCCA CTGCACTCCA GCCTGGGCGA CAGAGTGAGA CTCTGTCTCA AAAAAAAAAA AAAAGTGTTA TGATGCAGAC CTGTCAAAGA GGCAAAGGAG GGTGTTCCTA CACTCCAGGC ACTGTTCATA ACCTGGACTC TCATTCATTC TACAAATGGA GGGCTCCCCT GGGCAGATCC CTGGAGCAGG CACTTTGCTG GTGTCTCGGT TAAAGAGAAA CTGATAACTC TTGGTATTAC CAAGAGATAG AGTCTCAGAT GGATATTCTT ACAGAAACAA TATTCCCACT TTTCAGAGTT CACCAAAAAA TCATTTTAGG CAGAGCTCAT CTGGCATTGA TCTGGTTCAT CCATGAGATT GGCTAGGGTA ACAGCACCTG GTCTTGCAGG GTTGTGTGAG CTTATCTCCA GGGTTGCCCC AACTCCGTCA GGAGCCTGAA CCCTGCATAC CGTATGTTCT CTGCCCCAGC CAAGAAAGGT CAATTTTCTC CTCAGAGGCT CCTGCAATTG ACAGAGAGCT CCCGAGGCAG AGAACAGCAC CCAAGGTAGA

GACCCACACC CTCAATACAG ACAGGGAGGG CTATTGGCCC TTCATTGTAC CCATTTATCC ATCTGTAAGT GGGAAGATTC CTAAACTTAA GTACAAAGAA GTGAATGAAG AAAAGTATGT GCATGTATAA ATCTGTGTGT CTTCCACTTT GTCCCACATA TACTAAATTT AAACATTCTT CTAACGTGGG AAAATCCAGT ATTTTAATGT GGACATCAAC TGCACAACGA TTGTCAGGAA AACAATGCAT ATTTGCATGG TGATACATTT GCAAAATGTG TCATAGTTTG CTACTCCTTG CCCTTCCATG AACCAGAGAA TTATCTCAGT TTATTAGTCC CCTCCCCTAA GAAGCTTCCA CCAATACTCT TTTCCCCTTT CCTTTAACTT GATTGTGAAA TCAGGTATTC AACAGAGAAA TTTCTCAGCC TCCTACTTCT GCTTTTGAAA GCTATAAAAA CAGCGAGGGA GAAACTGGCA GATACCAAAC CTCTTCGAGG CACAAGGCAC AACAGGCTGC TCTGGGATTC TCTTCAGCCA ATCTTCATTG

CTCAAGTATG ACTTTAATCT TCCTTACAAC TAGGTGCTAA GGGAGTCTCT CTGTCTCTCT GCCTCTTTGT GTGTATGCAT ATTCTCTCTC TCTCTCTCTT TCTTTCTCTG TCTCTCCTCT CCTTCCTCTG TGCCTCCTCT CTCAGCTTTT TGCAAAAATG CCAGGTGTAA TATAATGCTT ATGACTCGGG AAATATTCTG GGAATGGATA CTGCTTATCT AACAGCTGAC ACCCTAAAGG TTAGTGTCAA AGCCTCTGCT CCAGCTCTCC TAGCCAATAC ATTGCTAGTT GGGGTTTGGT TTAGCAAATG CTTTTCTCTA GACCCAAAGG ACTTCTCTTT CACACATTCA TTCATTTACT CAGAGATCAT TTCTTTGCAT GACTGCCATG CACTGGATGC TGAGAGAAAT CACACATGAA CGTAGCCGTC ATGGGGAAGT CACTCATTTT CTCCTTTTTA CACAGGTGTC TGAAGCAGCC ATGGCAGAAG TACCTGAGCT CGCCAGTGAA ATGATGGCTT ATTACAGGTC AGTGGAGACG CTGAGACCAG

TAACATGAGC AGGTCTCCTC TTTCAAGAGT AGAGTGTTAT CTGTGCTTGG AGACCAGATT TTTCCCCTAA ATTGCCTCTT TCAGTGGCAA ACAGGGTGCC AAGTAAATCT GATTTAAAGA CTACTTTCCC ATTACAAGTC CCTCCAGCCT TGGGACCTGG AGGCTATCCA GATGTGTTGT TGCAAGGGCT TCCTGCAGAG GCAAATGGGG AGAAAAGATT CCAAGCCCAC AATACAAGGA ATCCCTTTGC AAAGTGTGGC TTGGAGGGAG AGGGAGAGCT CAGATTTTAG CTGACTCTGC TGGGCTAGAG GTTAGGCCTC AAGATCCAAC AGGGAGCACC AGGGTGCCCA CCTGCCAGGC CTAGAATCTG CCTTCTGGAC TGTTCTGCGC ATATCACTGT GAAACTTGCC AGGTGTTTCA GGCAGCTTTG AGAGGCAGGC TGTTTGCAGT TTCTTATGAA CAGTCAAGTC TTGTACACAG GGAAGGAAAA ATAAACCTGT TTAGAAGACA TAATTGAGAC ATGTCCCTGT TTTTATTACA GTGGCAATGA

GGATGACTTG TTCTTTGAAG CTGATGGCCC TAAACAGATG AAGGTAAGAC TATGGGTTTA ACTCCCAACC CAAGGAAGGG CTCTAACACA GGGAAAGCTC AAAGAAGGGA GTTCTGGGCC ACTTTGATGC CATGGTATTT TGTTTTAGAA AGACTTTAAC CTCTTCCAGT GAGACACAGG CTGCACCACT TGCTGACCTG GCCACTTGGT CATCATATCA CCACAGTCAC TCACTAACGT TGGTGGTGGT GGCCACACTT GGTGGTGACA GGGGAGGAGT AGTGATAATG TTCCCATTTC ATAGTAGGAA GACAACCAAG TCTTCAACAT AAATTTGATT ATCCTTTTAA GAGATGGATT CAGCCTATGC CAATCACTTG AGTTAAACTC TGAAACCAAG AGATGATCTT GAGAACTAAC ATATGTCTAC CCCTTTTGAG TAGAATAGTT TTTTGCTACC TGGGGTGAAG CTTATAACAA CAAGACATAG ATGATATAAA CAAAAAGATG AATTGAGACT TGAAAGAAAA CCATTCACTT GCTGTTTGAC

CTTGACAAGT CATTTTACCC GCTTTGGACC TCATCTGAAA AATAAAGGGC TGAGCTGGAT GATCTCTGAG ATTCCAGCAT CCTGCAACCT CCAGTTCTGA AATATTTTCA GTTGTAGCTA AGGGCATTTG GGCAGCAAAT GGTCATTTTT CAGACTCATC CTTACAAAGA GCCATGTTAT ATTCCTGCTG TCCCTTCTGT TTTATATGAT GCTCAGTAGC CTTCCTAGGT GCCCAGCCAT CAGCCTAGCT AGGTCAGTTG TGCAGGTTGG AGGCAGCCAC TTTTCTCTGG CTTTATTTTA TTCCAGTTTG TGATAGCCTC CCCTAGCCTC ATAATCCAGT CCTCAATCTT GTTAAAAACA TATTTCTTTA GAAGTTTTAA GACTGGCATA ACTTCTTGGC TGCAGCTGTG GGAGGAGCCC ATTGGCTTGT CTGCCTGGCC TTTGCCCCCC ATTGCCTCTT CCAGCAGCTT GGCTCTGCTC CAGGCAGGAA ATTCTCTCCT GCTCAACTTT CTTTTGTGCA CTTACAGGTC TCTTTAACTG TCTTTCAAGC

CTTTGAACCA TTATCAGCCT TAAGGCAACC TCAGTGAAGC CTTAATACGG AGCTTCTCTG AATAAGAGGA AAGTGGTAAC ATTTCACAAA AAGTACTCTC ACAGGATTTG CAGAATGCCT ATGAGACAGT GTTATGAAAA AGGAAAAAAA AGAACAGTGT AGAAAAATTG AATACTTGCT GAGTGAGCAT AGGTGAATGG AAAATGTTAT GGTCATCTGC ATGAAAAAGC AAATCATAGT GTGACAGCAT TAGGGATACA AAAAGATATA GAGAAGGTAT ACATGTATGG TGTAGGTGGG GCATGTACAA AAAGATGACA AGTAGAATCG GGATTTATTC TAAAGAATAG CCTGTAAGGT GTCCAGAAGC CACATTCTAG TCTTGAGTCT GCCTCTACCT GCTGTGTGCC CTTGAGTACA CCCTTAACCT CCTTGAGCTT CAGAGAGGGA TAATCTTTTT ATTTTATTTT ATTTTATTTT GTTTTGTTTT GTTTTGTTTT GTTTTATGAG ACAGAGTCTC ACTCTGTTGC CCAGGCTGGA GTGCAGTGGT ACAATCTTGG CTTACTGCAT CCTCCACCTC CTGAGTTCAA GCGATTCTCC TTCCTCAGTC TCCTGAATAG CTAGGATTAC AGGTGCACCC CACCACACCC AGCTAATTTT TGTATTTTTA GTAGAGAAGG GGTTTCGCCA TGTTGGCCAG GCTGGTTTTG AAGTCCTGAC CTAAATGATT CATCCACCTC GGCTTCCCAA AGTGCTGGGA TTACAGGCAT GAGCCACCAC GCCTGGCCCA GAGAGGGATG ATCTTTAGAA GCTCGGGATT CTTTCAAGCC CTTTCCTCCT CTCTGAGCTT TCTACTCTCT GATGTCAAAG CATGGTTCCT GGCAGGACCA CCTCACCAGG CTCCCTCCCT CGCTCTCTCC GCAGTGCTCC TTCCAGGACC TGGACCTCTG CCCTCTGGAT GGCGGCATCC AGCTACGAAT

CTCCGACCAC CACTACAGCA AGGGCTTCAG GCAGGCCGCG TCAGTTGTTG TGGCCATGGA CAAGCTGAGG AAGATGCTGG TTCCCTGCCC ACAGACCTTC CAGGAGAATG ACCTGAGCAC CTTCTTTCCC TTCATCTTTG AAGAAGGTAG TTAGCCAAGA GCAGGCAGTA GATCTCCACT TGTGTCCTCT TGGAAGTCAT CAAGCCCCAG CCAACTCAAT TCCCCCAGAG CCAAAGCCCT TTAAAGGTAG AAGGCCCAGC GGGGAGACAA AACAAAGAAG GCTGGAAACC AAAGCAATCA TCTCTTTAGT GGAAACTATT CTTAAAGAAG ATCTTGATGG CTACTGACAT TTGCAACTCC CTCACTCTTT CTCAGGGGCC TTTCACTTAC ATTGTCACCA GAGGTTCGTA ACCTCCCTGT GGGCTAGTGT TATGACCATC ACCATTTTAC CTAAGTAGCT CTGTTGCTCG GCCACAGTGA GCAGTAATAG ACCTGAAGCT GGAACCCATG TCTAATAGTG TCAGGTCCAG TGTTCTTAGC

CACCCCACTC CCAGCTTCAT CCCTACTGGT GTTGTCATCA GACTTTGACC GTATATGCTC AGGTGTCCTC CAAGAAATCA AATTTTGCCA CCTCGCCTCA CGAGGCCTGC CCTTCTGATT TTATACCTAA ACAACATGTG CTCCACATTT CAGAACCTAT CTTCTTCGAC ACATGGGATA ACGAGGCTTA TGTGCACGAT GCACCTGTAC GATCACTGAA CTGCACGCTC CGGGACTCAC AGCAAAAAAG CTTGGTGATG TCTGGTCCAT ATGAACTGAA AGCTCTCCAC CTCCAGGGAC AGGATATGGA GCAACAAGGT AAATGGAAAC ATCCTGGTTT CCCTGCCTGG CCTCCTGGCA GCTTGCTAAT TCTCCATGTT TTAAACAAAG TAGAAAGTTA ATTTAAGGCA AATGATCAAC ACAAGTGAAA AAAAATATTA AAAAGGAATA TACAAACTTT GGTCCTAGAA ATGGCACATT TGATTGCACT GGCCAGTGCA TTTGTTAACA GGAGTGTGAC CCTGAGAAAT TAGACGGCTC AAGCACTCCC

AGGACCATGT CCACCCAAGT CTCTTGGGCA TAGTGCAGTG TCAATTCTTC CACAATATGG GGTCATTTGA TGGACATGGC CTAACTGCCT GTGGGTTCTC TCTTCCTGTT GTTGAGGCTG AAACAAGAGT GCTGGAGCGA TAATGTGTCC ATCCCCCTCC CCAGTCTTCC CCCCTTGCCC CAACATCCGT CCCACCCAAT GCCAGGTGGT TCCTTGTAGG GAAATTTTAC CGCCCAGCAG GAACTTATAT CTCTCCGCTG TAACGGGCAA AAGTTTCAAG TGCGGTGAAC CCATCATTAG CTGTGGTGAT CTGCCTGGCA TCGTGCCACA GTAGCCAAAG CCTCTGCACA GGAGTGTGGG CAACTAAGGC TGCTGACTTT GAAGGACAGC CTCACTCAGG GGGAAGCTAT TTGCTCTCAG CCAGGCCAAG AAAATCCTGT TTCTTTGGAA TCGGGTAGTA AGAGTGATCC CAGGGCCTCC AATTGACACT GCTGTGACTG AGGAAGATCA AAATGAGTGT CTCTCTTTGG AGCCACTTTC CCAGCTCAGC

CTCTCCTCTC CCAGTTTCTT CCCATGGGCT ACTCTCTGTT CCTGAAACAG TTCTGGTGCC TGATTTCTGG CAGAAGTACA GCTTCACCTC TTTCCTTTCC TTCCACATTG ATCAAGTTGT TCCGCTCCTG TGGATGGGCA CATTGCCAGC CAGTGACACA ATGGCTTCCT TCCTTCCTTC CTTCAGCATT TAAAATGTAG ACCCTCTTTC ATTCTCCGTT CCTACTGCTA TGAGGCTCTG AGAAACCCTC AGGCCTTTGA GGGGAAACCC TAAATCAACA AAATGACCCT GCTATTGTCT GTGAGAAGTC AAGTTATCCT GTGTCTTAGG CCAAGGAACC TCACTGTGGG TTCCCACAGA GGCTACCAAT TACATGTATC CTACTCTCGG GGCTAGGGGT TGGGGTGACC CTGCATGCTG TGTCCCTAAC CACAAGACCC CCTTCTTTCT TCAGTGGTGT TCTCCATGTC CTTTGTACAA GGAGAAGAAA GTAATGACAA AATACCTGTG GCCTTGGGCC TCAAGGAAAA GAATCTGTAC CTGTCCTGCG

TGTTGAAAGA TGATAAGCCC ACTCTACAGC TGGAGGTAAG TGAATGCTAT GGAATGAAGC CCTTCTCAGC CTCCTGCTAC CACTTATTCC CAGACAATTC ACCTTCTCCC CGCCCCCATC CCTAGGAAAA GCTGGGAACA GGTCTATTTG ACAAGTTTTG CATTAATGTA AATAAATTTA ACATAATTTT TAACTGCGTG CAACCTTCAA TCCTGCTGCA GAAAATTAAA TCATTTTGCC GATGTTATTA TGTCCTACCA TAGTTACAAC CCCAACAGAT TATATATTGT TAGGGCTGCT CTCATTTGAT AGACACCTTG GGAAATAGAT GACTTAAAGG GTCCCATTAT CACGTCCACT CCACTCCCAA AATCACCACC ACTATCACCT CCAGCTTTCT CAGCAAAAGC TTCATTTCCA. AGTTGATGTC ATTCTAGGAC CATAAGGAAA AATACAATAA AAAGCCCCTG GAAACTAGGT ACTTCAAGAA GCTCTAGCTT AATTTTCACC CCCCCAAAAA AAAAAAATTC TCACCTACAT TATGCTCCTC

AGCATTTGGC ACTAAGTTTT AGAAAAGAAG AAGGGCTCTT TTAATAATCA CACAGAAAGT TGGGGGCCCA GTTACAACTC AGGAGTCTGG CTCCTGATCA TGTGACCTGC TCGTCAGTTT CCTTTCTGGC CAACCCAAAG AACATCTTTC CCATAGGCAT CTTTGTCCCT TGCCCCACAA AAATTCTTCT TTCTCTTTCG CTGCAGAGTG TAGATCCCAA AAATTACCCA AAGAAGAAGA TGGAAAAGCG ATTTGTCTTC AACAAGATAG AAATCAATAA CAAGCTGGAA TTTGAGTCTG CCCAGTTCCC CAACTGGTAC ATCAGCACCT CTCAAGCAGA AAACATGCCC GTCTTCCTGG GAGGGACCAA AGGCGGCCAG GATATAACTG ACTTCACCAT GCAATTTGTG TCTTCCTAAA GAGAGCTGTA CCCAGAGAGT CCTGTGCTGA ATGTGGACTC AATCCCTAGG GCTGGCAGAA AGGGAACAGA AAGGTTTTTG AGTACGGCTA TAGCCTGGAC TTTCCTGTTG TCTACACCAA TGCCCAACTG

CCTGCCTTAG GGTAGTGCTA AGAGGATCTC CTGTCCATCA GCCAGGACAG TCAGCTCTCT CCTTTCAGGG CCAATCCCCA GCCCTTTTGT TGAGCCAGGC CTCTCTCACC TCTCCTACTC ACTTAAAGCC CGCCTGACAG AAACCACGGC CACATTTGGT TCTAAGAAAC CCTCTGTCAT TCGCTCCCAC ATTCTGATGA GCAACCGCTT CCCTATTTAT TTATTTATTT GTTTGTTTGT TTTGATTCAT TGGTCTAATT TATTCAAAGG GGGCAAGAAG TAGCAGTGTC TGTAAAAGAG CCTAGTTTTT AATAGCTATG GAATCAATTC AATTTGGACT GGTGTGCTCT CTTTAAATCA AGTCCTTTAA TTAAGACTGA AAATATATAA GCTCAGATTA TTTAAATGGG AATATTTATA AATGAGCAAA TATCATACTG TTCAATGGTT CTGAAATAAA CTTCACTGAA GAAAAAAAAA AAAGGGTCTC TCCTGATCAT TGACTGTCTG GATTGACACT GACAGTAAGC AAACAGGCTG TGAGAGTTCT

TGGGACTAAG CCCACTCCTC ATTGCTGAGT GCTGCAAGTA CCTAGAAATA TCCTTGGCCA CCGAAGACTA TCCTCCTCAC CCATCCCCTT TATTTCGTTG TTCAACAGAA GGATATTCAG TGCACATCTG GAACAGGATC AGCTGAAGCA CTGCAGGGAG TCAGGACTGG TAGTAACAGC TACCATGATT TATCTATCAA TGCACCAAAC ATCTGTTGAG CAAGCGCTAT GTACTAGGAG CTGGGAGTAC AGAGATGAGA ACAGTCACAA GTCCCTCCTC AGATAGGAGA GGCAGCTAGT TATAAGCAGA ACAAGGTAAC ATGACAAGTA GAGTAAGATA GAAGAACGAA GAGGAGTAGC CAGGAAGGAG GGAGGAGAAC GACATAAGAA TCAAGCCTAA AGGGATAAAC AGAAGATTTC CACACATGGG CTGGGCCAAT TGGGTGTCGG TTACGCCTGT AATCCCAGCA CTTTGGGTGG CAGGGGCAGA AAGATCGCTT GAGCCCAGGA GTTCAAGACC AGCCTGGGCA

ACATAGTGAG ACTCCCATCT CTACAAAAAA TAAATAAATA AATAAAACAA TCAGCCAGGC ATGCTGGCAT GCACCTGTAG TCCTAGCTAC TTGGGAAGCT GACACTGGAG GATTGCTTGA GCCCAGAAGT TCAAGACTGC AGTGAGCTTA TCCGTTGACC TGCAGGTCGA C ACAAACCTTT TCGAGGCAAA AGGCAAAAAA GGCTGCTGTG GGATTCTCTT CAGCCAATCT TCAATGCTCA AGTGTCTGAA GCAGCCATGG CAGAAGTACC TAAGCTCGCC AGTGAAATGA TGGCTTATTA CAGTGGCAAT GAGGATGACT TGTTCTTTGA AGCTGATGGC CCTAAACAGA TGAAGTGCTC CTTCCAGGAC CTGGACCTCT GCCCTCTGGA TGGCGGCATC CAGCTACGAA TCTCCGACCA CCACTACAGC AAGGGCTTCA GGCAGGCCGC GTCAGTTGTT GTGGCCATGG ACAAGCTGAG GAAGATGCTG GTTCCCTGCC CACAGACCTT CCAGGAGAAT GACCTGAGCA CCTTCTTTCC

CTTCATCTTT GAAGAAGAAC CTATCTTCTT CGACACATGG GATAACGAGG CTTATGTGCA CGATGCACCT GTACGATCAC TGAACTGCAC GCTCCGGGAC TCACAGCAAA AAAGCTTGGT GATGTCTGGT CCATATGAAC TGAAAGCTCT CCACCTCCAG GGACAGGATA TGGAGCAACA AGTGGTGTTC TCCATGTCCT TTGTACAAGG AGAAGAAAGT AATGACAAAA TACCTGTGGC CTTGGGCCTC AAGGAAAAGA ATCTGTACCT GTCCTGCGTG TTGAAAGATG ATAAGCCCAC TCTACAGCTG GAGAGTGTAG ATCCCAAAAA TTACCCAAAG AAGAAGATGG AAAAGCGATT TGTCTTCAAC AAGATAGAAA TCAATAACAA GCTGGAATTT GAGTCTGCCC AGTTCCCCAA CTGGTACATC AGCACCTCTC AAGCAGAAAA CATGCCCGTC TTCCTGGGAG GGACCAAAGG CGGCCAGGAT ATAACTGACT TCACCATGCA ATTTGTGTCT TCCTAAAGAG AGCTGTACCC AGAGAGTCCT

GTGCTGAATG TGGACTCAAT CCCTAGGGCT GGCAGAAAGG GAACAGAAAG GTTTTTGAGT ACGGCTATAG CCTGGACTTT CCTGTTGTCT ACACCAATGC CCAACTGCCT GCCTTAGGGT AGTGCTAAGA GGATCTCCTG TCCATCAGCC AGGACAGTCA GCTCTCTCCT TTCAGGGCCA ATCCCAGCCC TTTTGTTGAG CCAGGCCTCT CTCACCTCTC CTACTCACTT AAAGCCCGCC TGACAGAAAC CAGGCCACAT TTTGGTTCTA AGAAACCCTC CTCTGTCATT CGCTCCCACA TTCTGATGAG CAACCGCTTC CCTATTTATT TATTTATTTG TTTGTTTGTT TTGATTCATT GGTCTAATTT ATTCAAAGGG GGCAAGAAGT AGCAGTGTCT GTAAAAGAGC CTAGTTTTTA ATAGCTATGG AATCAATTCA ATTTGGACTG GTGTGCTCTC TTTAAATCAA GTCCTTTAAT TAAGACTGAA AATATATAAG CTCAGATTAT TTAAATGGGA ATATTTATAA ATGAGCAAAT ATCATACTGT

TCAATGGTTC TCAAATAAAC TTCACT CTGGCAGGAG TAGCAGCTGC CCCTTGGCGC GACTGCTGGA GCCGCGAACT AGAGAAACAC AGACACGCCT CATAGAGCAA CGGCGTCTCT CGGAGCGTGG AGCCCGCCAA GCTCGAGCTG AGCTTTCGCT TGCCGTCCAC CACTGCCCAC ACTGTCGTTT GCTGCCATCG CAGACCTGCT GCTGACTTCC ATCCCTCTGG ATCCGGCAAG GGCCTGCGAT TTTGACAATG TCAAGATTTA CCGTATATCC CTGTTTGTTT GGATACACCA GTGACGTCCA CTTCTAGAAG ACAAAGTTAT ATTACTTAAA CAACCAAAGA TATGAAACTA TCCATGAAGA ACAATATTAT CAATACACAG CAGTCTTTTG TAACCATGCC CAATGTGATT GTACCAGATA TTGAAAAGGA AATACGAAGG ATGGAAAATG GAGCATGCAG CTCCTTTTCT GAGGATGATG ACAGTGCCTC TACATCTGAA GAATCAGAGA ATGAAAACCC TCATGCAAGG GGTTCCTTTA

GTTATAAGTC ACTCAGAAAG GGAGGACCAT CACAGAGGGA GCAGTACCTG CCTGGTGCCA TTGCCATTTT TAATGTGAAC AACAGCGACA ATAAGGACCA GGAACCAGAA GAAAAAAAGA AAAAGAAAAA AGAAAAGAAG AGCAAGTCAG ATGATAAAAA CGAAAATAAA AACGACCCAA AGAAGAAGAT GGAAAAGCGA ATGGCCAAAG TTCCAGACAT GTTTGAAGAC CTGAAGAACT GTTACAGTGA AAATGAAGAA GACAGTTCCT CCATTGATCA TCTGTCTCTG AATCAGAAAT CCTTCTATCA TGTAAGCTAT GGCCCACTCC ATGAAGGCTG CATGGATCAA TCTGTGTCTC TGAGTATCTC TGAAACCTCT AAAACATCCA AGCTTACCTT CAAGGAGAGC ATGGTGGTAG TAGCAACCAA CGGGAAGGTT CTGAAGAAGA GACGGTTGAG TTTAAGCCAA TCCATCACTG ATGATGACCT GGAGGCCATC GCCAATGACT CAGAGGAAGA AATCATCAAG CCTAGGTCAG

CACCTTTTAG CTTCCTGAGC AATGTGAAAT ACAACTTTAT GAGGATCATC AAATACGAAT TCATCCTGAA TGACGCCCTC AATCAAAGTA TAATTCGAGC CAATGATCAG TACCTCACGG CTGCTGCATT ACATAATCTG GATGAAGCAG TGAAATTTGA CATGGGTGCT TATAAGTCAT CAAAGGATGA TGCTAAAATT ACCGTGATTC TAAGAATCTC AAAAACTCAA TTGTATGTGA CTGCCCAAGA TGAAGACCAA CCAGTGCTGC TGAAGGAGAT GCCTGAGATA CCCAAAACCA TCACAGGTAG TGAGACCAAC CTCCTCTTCT TCTGGGAAAC TCACGGCACT AAGAACTATT TCACATCAGT TGCCCATCCA AACTTGTTTA TTGCCACAAA GCAAGACTAC TGGGTGTGCT TGGCAGGGGG GCCACCCTCT ATCACTGACT TTCAGATACT GGAAAACCAG GCGTAGGTCT GGAGTCTCAC TTGTCTCACT TGTGCAGTGT TGACAGTTCA TATGTACCAT GTACATGAAG AAGCTAAATC

CTTTACTGTT AGTCATTTGC TGAGCATGTA CTGAGCCTTG TAATTCTAAA TGAATGTTTA CACTCTTTGT AAGAGTGGAA CCAACACTAA CATATAATGT TGTTATTTAA AGAACACCCT ATATTTTGCA TAGTACCAAT CATTTTAATT ATTATTCTTC ATAACAATTT TAGGAGGACC AGAGCTACTG ACTATGGCTA CCAAAAAGAC TCTACCCATA TTACAGATGG GCAAATTAAG GCATAAGAAA ACTAAGAAAT ATGCACAATA GCAGTTGAAA CAAGAAGCCA CAGACCTAGG ATTTCATGAT TTCATTTCAA CTGTTTGCCT TCTGCTTTTA AGTTGCTGAT GAACTCTTAA TCAAATAGCA TAAGTTTCTG GGACCTCAGT TTTATCATTT TCAAAATGGA GGGAATAATA CCTAAGCCTT CCTGCCGCAA CAGTTTTTTA TGCTAATCAG GGAGGTCATT TTGGTAAAAT ACTTCTCGAA GCCGAGCCTC AAGATGAAGG CAAAGCACGA AATGTTATTT TTTAATTATT ATTTATATAT

GTATTTATAA ATATATTTAA GATAATTATA ATATACTATA TTTATGGGAA CCCCTTCATC CTCTGAGTGT GACCAGGCAT CCTCCACAAT AGCAGACAGT GTTTTCTGGG ATAAGTAAGT TTGATTTCAT TAATACAGGG CATTTTGGTC CAAGTTGTGC TTATCCCATA GCCAGGAAAC TCTGCATTCT AGTACTTGGG AGACCTGTAA TCATATAATA AATGTACATT AATTACCTTG AGCCAGTAAT TGGTCCGATC TTTGACTCTT TTGCCATTAA ACTTACCTGG GCATTCTTGT TTCATTCAAT TCCACCTGCA ATCAAGTCCT ACAAGCTAAA ATTAGATGAA CTCAACTTTG ACAACCATAG ACCACTGTTA TCAAAACTTT CTTTTCTGGA ATGTAATCAA TGTTTCTTCT AGGTTCTAAA AATTGTGATC AGACCATAAT GTTACATTAT TATCAACAAT AGTGATTGAT AGAGTGTTAT CAGTCATAAC TAAAT AAAGC TTGCAAGTGA GGGAGTCATT TCATTGGCGT TTGAGTCAGC

AAAGAAGTCA AG AGCTGCCAGC CAGAGAGGGA GTCATTTCAT TGGCGTTTGA GTCAGCAAAG AAGTCAAGAT GGCCAAAGTT CCAGACATGT TTGAAGACCT GAAGAACTGT TACAGTGAAA ATGAAGAAGA CAGTTCCTCC ATTGATCATC TGTCTCTGAA TCAGAAATCC TTCTATCATG TAAGCTATGG CCCACTCCAT GAAGGCTGCA TGGATCAATC TGTGTCTCTG AGTATCTCTG AAACCTCTAA AACATCCAAG CTTACCTTCA AGGAGAGCAT GGTGGTAGTA GCAACCAACG GGAAGGTTCT GAAGAAGAGA CGGTTGAGTT TAAGCCAATC CATCACTGAT GATGACCTGG AGGCCATCGC CAATGACTCA GAGGAAGAAA TCATCAAGCC TAGGTCATCA CCTTTTAGCT TCCTGAGCAA TGTGAAATAC AACTTTATGA GGATCATCAA ATACGAATTC ATCCTGAATG ACGCCCTCAA TCAAAGTATA ATTCGAGCCA ATGATCAGTA CCTCACGGCT GCTGCATTAC

ATAATCTGGA TGAAGCAGTG AAATTTGACA TGGGTGCTTA TAAGTCATCA AAGGATGATG CTAAAATTAC CGTGATTCTA AGAATCTCAA AAACTCAATT GTATGTGACT GCCCAAGATG AAGACCAACC AGTGCTGCTG AAGGAGATGC CTGAGATACC CAAAACCATC ACAGGTAGTG AGACCAACCT CCTCTTCTTC TGGGAAACTC ACGGCACTAA GAACTATTTC ACATCAGTTG CCCATCCAAA CTTGTTTATT GCCACAAAGC AAGACTACTG GGTGTGCTTG GCAGGGGGGC CACCCTCTAT CACTGACTTT CAGATACTGG AAAACCAGGC GTAGGTCTGG AGTCTCACTT GTCTCACTTG TGCAGTGTTG ACAGTTCATA TGTACCATGT ACATGAAGAA GCTAAATCCT TTACTGTTAG TCATTTGCTG AGCATGTACT GAGCCTTGTA ATTCTAAATG AATGTTTACA CTCTTTGTAA GAGTGGAACC AACACTAACA TATAATGTTG TTATTTAAAG AACACCCTAT ATTTTGCATA

GTACCAATCA TTTTAATTAT TATTCTTCAT AACAATTTTA GGAGGACCAG AGCTACTGAC TATGGCTACC AAAAAGACTC TACCCATATT ACAGATGGGC AAATTAAGGC ATAAGAAAAC TAAGAAATAT GCACAATAGC AGTCGAAACA AGAAGCCACA GACCTAGGAT TTCATGATTT CATTTCAACT GTTTGCCTTC TGCTTTTAAG TTGCTGATGA ACTCTTAATC AAATAGCATA AGTTTCTGGG ACCTCAGTTT TATCATTTTC AAAATGGAGG GAATAATACC TAAGCCTTCC TGCCGCAACA GTTTTTTATG CTAATCAGGG AGGTCATTTT GGTAAAATAC TTCTCGAAGC CGAGCCTCAA GATGAAGGCA AAGCACGAAA TGTTATTTTT TAATTATTAT TTATATATGT ATTTATAAAT ATATTTAAGA TAATTATAAT ATACTATATT TATGGGAACC CCTTCATCCT CTGAGTGTGA CCAGGCATCC TCCACAATAG CAGACAGTGT TTTCTGGGAT AAGTAAGTTT GATTTCATTA ATACAGGGCA TTTTGGTCCA AGTTGTGCTT ATCCCATAGC CAGGAAACTC TGCATTCTAG TACTTGGGAG ACCTGTAATC ATATAATAAA TGTACATTAA TTACCTTGAG CCAGTAATTG GTCCGATCTT TGACTCTTTT GCCATTAAAC TTACCTGGGC ATTCTTGTTT CATTCAATTC CACCTGCAAT CAAGTCCTAC AAGCTAAAAT TAGATGAACT CAACTTTGAC AACCATGAGA CCACTGTTAT CAAAACTTTC TTTTCTGGAA TGTAATCAAT GTTTCTTCTA GGTTCTAAAA ATTGTGATCA GACCATAATG TTACATTATT ATCAACAATA GTGATTGATA GAGTGTTATC AGTCATAACT AAATAAAGCT TGCAACAAAA TTCTCTG GCTCAGGGCA CATGCCTCCC CTCCCCAGGC CGCGGCCCAG

CTGACCCTCG GGGCTCCCCC GGCAGCGGAC AGGGAAGGGT TAAAGGCCCC CGGCTCCCTG CCCCCTGCCC TGGGGAACCC CTGGCCCTGT GGGGACATGA ACTGTGTTTG CCGCCTGGTC CTGGTCGTGC TGAGCCTGTG GCCAGATACA GCTGTCGCCC CTGGGCCACC ACCTGGCCCC CCTCGAGTTT CCCCAGACCC TCGGGCCGAG CTGGACAGCA CCGTGCTCCT GACCCGCTCT CTCCTGGCGG ACACGCGGCA GCTGGCTGCA CAGCTGAGGG ACAAATTCCC AGCTGACGGG GACCACAACC TGGATTCCCT GCCCACCCTG GCCATGAGTG CGGGGGCACT GGGAGCTCTA CAGCTCCCAG GTGTGCTGAC AAGGCTGCGA GCGGACCTAC TGTCCTACCT GCGGCACGTG CAGTGGCTGC GCCGGGCAGG TGGCTCTTCC CTGAAGACCC TGGAGCCCGA GCTGGGCACC CTGCAGGCCC GACTGGACCG GCTGCTGCGC CGGCTGCAGC TCCTGATGTC CCGCCTGGCC

CTGCCCCAGC CACCCCCGGA CCCGCCGGCG CCCCCGCTGG CGCCCCCCTC CTCAGCCTGG GGGGGCATCA GGGCCGCCCA CGCCATCCTG GGGGGGCTGC ACCTGACACT TGACTGGGCC GTGAGGGGAC TGCTGCTGCT GAAGACTCGG CTGTGACCCG GGGCCCAAAG CCACCACCGT CCTTCCAAAG CCAGATCTTA TTTATTTATT TATTTCAGTA CTGGGGGCGA AACAGCCAGG TGATCCCCCC GCCATTATCT CCCCCTAGTT AGAGACAGTC CTTCCGTGAG GCCTGGGGGA CATCTGTGCC TTATTTATAC TTATTTATTT CAGGAGCAGG GGTGGGAGGC AGGTGGACTC CTGGGTCCCC GAGGAGGAGG GGACTGGGGT CCCGGATTCT TGGGTCTCCA AGAAGTCTGT CCACAGACTT CTGCCCTGGC TCTTCCCCAT CTAGGCCTGG GCAGGAACAT ATATTATTTA TTTAAGCAAT TACTTTTCAT GTTGGGGTGG GGACGGAGGG GAAAGGGAAG CCTGGGTTTT

TGTACAAAAA TGTGAGAAAC CTTTGTGAGA CAGAGAACAG GGAATTAAAT GTGTCATACA TATCC CAGCTGCGGC ATCCTCTGTC TCAGAGTCTT GGTGTCTCTG TTCCTTTCCC CTCGGGGTCT CCCTGGGTCT CCCCAAGTCC CTCCTGCTGT CTTCCTCCCG CTCTCTGATC TCTGACTCCC AGAACCTCTC CCTCTGTCTC CAGGGCTGCC CCTCTGATCC TCTTTGCTTC TCTGGTGTGT CTCTCTGGCT GCCTCCATCT CTGTGGATCT CCGTCTCCCT GTCTCTGTCT CAGTCTGTCC TTCACTCTGT GTGTGTGTGT GTCTCTCTCT CTCTCTCTCC TTCCCTTCCA CTCCCTCTTC CTCCTGCCTC CACCTCTCCA GGCCCCTGTC TTGTCCCTCC GTCCGGCCTT TCTCTGCCTT TCCGTCCTCC TGCCTCCCCA TCTCTCTCTG CTAGTCCTGT CCAGCCGGAC CCCCACCCAC AGTCGGGCCC CAGCGCTTGA GCCTGAGTGT CTGCTCCGGC CCGTGGAGGT GGAGGGAGGG

GACGCCAATG ACCTCACCAG CCCCTCTCCG ACCACCCCCC CCTTTCCCTT TTCAACTTTT CCAACTTTTC CTTCCGTGCC CTCCTCCGAG CGCGGCGGCG TGAGCCCTGC AAGGCAGCCG CTCCGTCTGA ATGGAAAAGG CAGGCAGGGA GGGTGAGTCA GGATGTGTCA GGCCGGCCCT CCCCTGCCGC CTGCCCCCCG CCCGCCCGCC CCAGGCCCCC TATATAACCC CCCAGGCGTC CACACTCCCT CACTGCCGCG GGCCCTGCTG CTCAGGGCAC ATGCCTCCCC TCCCCAGCCG CGGGCCCAGC TGACCCTCGG GGCTCCCCCG GCAGCGGACA GGGAAGGGTT AAAGGCCCCC GGCTCCCTGC CCCCTGCCCT GGGGAACCCC TGGCCCTGTG GGGACATGAA CTGTAAGTTG GTTCATGGGG AGGGTGGAGG GGACAGGGAG GCAGGGAGGA GAGGGACCCA CGGCGGGGGT GGGAGCAGAC CCCGCTGAGT CGCACAGAGA GGGACCCGGA GACAGGCAGC

CGGGGAGGAG AGCAGCTTCG GAGACAGGAG GCGGCGGAGG AGATGGGCAG AGAGAGACAC AGACAGGAGC GGATGGAGGC AGCCAATCAG AGGCGCCGCA GGAGGGACGG GCCAGACAGG GCCCGAGAGG AGCGAGACGC GAGACCGAGC AGGGGCAGGG ACGCAGGGAC TGGTGCCGGG AGGGAGGTGA CCCCCATCGA CCCAGGCCCC AGGGAGCCCG CGGGGACCGG GAGACTCCCT GGGATTCCGG CAGAGAGGCT CCGGAGGGAA ACTGAGGCAG GGTCCGCGGA GAGCGGAGCA AGCCAGGGAG TAGCGACCCC AGCCGGGGGG AGGAGAGAGA CTGGGCGCCG GGGGAAAGCG GGGAGAGCCG GGCAGATGCG GCCGACGGAG GCGCGGACAG ACCGACGGCT GGCGGGCCCG GGGGGCGGGC TGGGGGTGTG CGAGGCGCGG GCGGCCGGGG AGCGCTGATT GGCTGGCGGG TGGCCGGGTG GGCGGGGCGG

CCGGGGTGGG CTGCGGGGAG CGAGCTCCGG ACCCCCGCGC CCCCGGCGCC CCCCGCGCCC CCCGCCGCCA GCTCTCCCGC TCCCGGCGCC CGGCCGGGCC ATGGCTCTGC CCCTCTCCGC CCAGGTGCGC TGCGGCCCGG GCTTCTGCCG CCCACCCGGC GGGCTCCTGG GAGGGCGTCT AAGGGGTCTC CCGTGGGAGA GGTCCGTGTC TCCCGGACTC CGTCCTGGGC TTTTGGCTCC TTCCCCTGCT CCCAGCCAGC TCGGGCTCCC GCGGCCCGGG GAGGGGGCAG GTTCTGGCCT GTGCCTCCCC CACCATCCGC GCCCCGGGGC CCAGATTCCG GCGTCCGGGG GCGGACGGGA GACGCCCGGG CCGCGTCTGC TCCGACGGGC GGGGCAGCCA GAGCCAGGGA GGGAGAGGGA AGCCCGCCTG GCCCTGCGAC CTGCCCGCGG GCGTTCCACC CTGGGACTTA AGACCTCCAG CTCCATCCTC CCTAAGGCCG GGAGTCCAGG CCCCAGACCC TCCTCCCCGA GACCCAGGAG

TCCAGACCCC AGGCCTTCCT CCCTCAGACC TAGGAGTCCA GGCCCCCAGC CTCTCCTCCC TCAGACCCAG GAGGAGTCCA GACCCCAGTT CCTCCTCCCT CAGACCCGGG AGTCCAGCCC AGGCCCTCCT CTCTCAGACC CGGAGTCCAG CCTGAGCTCT CTGCCTTATC CTGCCCCCAG GTGTTTGCCG CCTGGTCCTG GTCGTGCTGA GCCTGTGGCC AGATACAGCT GTCGCCCCTG GGCCACCACC TGGCCCCCCT CGAGTTTCCC CAGACCCTCG GGCCGAGCTG GACAGCACCG TGCTCCTGAC CCGCTCTCTC CTGGCGGACA CGCGGCAGCT GGCTGCACAG CTGGTAGGAG AGACTGGGCT GGGGCCAGCA CAGGAGTGAG AGGCAGAGAG GAACGGAGAG GAGTCTGCGG GCAGCCACTT GGAGGGGTTC TGGGCTCTCA GGTGGCAGAG TGAGGGAGGG GAAGAGTTGG GGGCCTGGCG TGGGGGATGG AGGGAGCCCC GAGGCTGGGC AGGGGCCACC

TCACAGCTTT TTTCCCTGCC AGAGGGACAA ATTCCCAGCT GACGGGGACC ACAACCTGGA TTCCCTGCCC ACCCTGGCCA TGAGTGCAGG GGCACTGGGA GCTCTACAGG TAAGGGCAAG GGAGTGGGCT GGGGACAAGG TGGGAGGCAG GCAGTGAAGG GGGCGGGGAG GATGAGGGGC ACTGGTCGGG TGTTCTCTGA TGTCCCGGCT CTATCCCCAG CTCCCAGGTG TGCTGACAAG GCTGCGAGCG GACCTACTGT CCTACCTGCG GCACGTGCAG TGGCTGCGCC GGGCAGGTGG CTCTTCCCTG AAGACCCTGG AGCCCGAGCT GGGCACCCTG CAGGCCCGAC TGGACCGGCT GCTGCGCCGG CTGCAGCTCC TGGTATGTCC TGGCCCCAAG ACCTGACACC CCAGACCCCC ACCCCTGGCC CCAAAATCCT GTGGCCTGAG TCCTTGAAGC CTGAGACCCC AGACCCGAGT GCAACAGCCC CGCTCTGAGA CCCTGACACC CTAACAGCCC GCTCTGAGAC CCTGACACCG

TAACAGCCCC GCTCTGAGAC CCTGACCCTA ACAGTCCTGC TCTGAGACCC TGACCCTGCA GTCCCAAGAT CCTGTGGCCC TGAGACCCTG AGGCCCTAGA CCCCCAAATC CTGCCCAGAA ACTTCAAATT CTCACCCAAG ACCCTGAGAC TCCATCATCC ATGACCTCAA AGTCCCCAGA TCCCAGCCCC TAAGACCCAA GACCCCATCC TGAAGCCCAA AGCCTTGAGA ATTCAAATCC TCACCTCAAG ACTTGGAGAC CCTGGCCCCA TGACATTGAA AACCATGGAC CTGGCCAGGC GTGGTGGCTC ACGCCTGTAA TCCCAGCACT TTGGGAGGCC GAGGCAAGTG GATCACCTGA GGTCGGGAGT TCAAGACCAG CCAGACCAAC ATGGTGAAAC CCTGTCTCTA CTAAAAATAC AAAATTAGCC AGGCGTGGTG GTGCATGCCT GTAATCCCAG CTACTTGGGA GGCTGAGGCA GGAGAATCGC TTGAACCTGG GAGGCGGAGG TTGCAGTGAG CCGAGATCGC ACCATTACAC TCCAGCCTGG

GCAACAAGAG CAAAACTCCC TCTCTCTCAA AAAAAAAAAA AAAAAAAAAA AAGAAGGAAA AGAAAACCAT GGACCTCCAG ACCCTGAGAC CCCAGGCCCC AGCCCTGAGA TCCTGACATC TTAAAGATCC CAGGCCCTAA GATACAAGAC CTTGACCCAA AGCCAGCCTT GGGACCCTGG CTGTACAAAC CCAAGACCTC CAGGACCTAG ACCCCGAGCC CTGAGGCCCT ATGTCTCACT CCCAACATCG AAAACCCTGA CACCTCAGAT CCTGAGCCTG CGCCTGTACG ACTCCAAGAC CCTGACTTCC AAAGCCAGGC CCAAAGCCCT GAGACCAGAA GACTTCAAAC CCTGGTTCTT GGGCCTAACT CCAAAGACCC TGGATCTCAA ATTCCAACTT CTAGCTCTGA GACTCCAGCC CTCACCCATG AGTTCCTGAA CTTGAACCCA GAGACCCCAT CTCTAAGACT TCAGCCTTGA GATCCAGGGC CTGACCCTAG ACTCGAGCCC ACAGACCTCA GATACTGTCT GTAAAACCCC

AGCTCTGGTG GGGAGCAGTG GCTCACTCCT GTAATCCCAA GGCAGGGGAG GCCAAGGCAG AAGGACCTCT TGAGGCCATG AGTTTGAGAC AGCCTGGGCA GCATAGCAAG ACTCTGTTTC TTAATTATTA TTATTATTAT TATTTTTTGG AGACAGAGTC TCGCGCTCTG TTGCCCAGGC TAGAGTGCAA TGGTGCCATT TCGGCTTGCT GGAACCTCCG CCTCCTGGGC TCAAGCGATT CTCCTGCCTC AGCCTCCTGA GTAGCTGGGA CTTCAGGTGC ACACTGCCAC ACCCGGATAA TTTTTTTGTA TTTTAGTAGA CACAGGGTTT CACCGTGTTG CCCAGGCTGG TCACAAACTC CTGAGCTCAG GCCATCCGCC CGCCTCGGCC TCCCAAAGCG CTGGGATAAC AGGCGTGACG CCGCGCCTGG CTTCTTAATT GTTCTAACAG CAGCGACAAC AACAAAAACC CAGCTCTGAG ATTCCAGCCC CGGCGACTCT AACAGTCCCA GGCCCGATCC CTCACCTAGA ACCGAGATGC

CAGCCCTGAC TCCACAGACT TCACCCCCAA CCCCCACACT CAGCTCTGGA AGCCCGTCCT GACTCCAGCC TCCATTTTCG GAACCCCACA GCCTGAAGAG CTCCCGGCCT AAACACTTCA CCCCACGCGC CACAGTCCCC CTGTGAATAT GCAGCCCCGA TTCAGCTGCA GCTCCACAGC ACCCCTGCCC TGCACCCCCG CTGCACCCCC TACCTGTGAC TCACCTCTCT CCTCTCCCCA CAGATGTCCC GCCTGGCCCT GCCCCAGCCA CCCCCGGACC CGCCGGCGCC CCCGCTGGCG CCCCCCTCCT CAGCCTGGGG GGGCATCAGG GCCGCCCACG CCATCCTGGG GGGGCTGCAC CTGACACTTG ACTGGGCCGT GAGGGGACTG CTGCTGCTGA AGACTCGGCT GTGACCCGGG GCCCAAAGCC ACCACCGTCC TTCCAAAGCC AGATCTTATT TATTTATTTA TTTCAGTACT GGGGGCGAAA CAGCCAGGTG ATCCCCCCGC CATTATCTCC CCCTAGTTAG AGACAGTCCT TCCGTGAGGC

CTGGGGGGCA TCTGTGCCTT ATTTATACTT ATTTATTTCA GGAGCAGGGG TGGGAGGCAG GTGGACTCCT GGGTCCCCGA GGAGGAGGGG ACTGGGGTCC CGGATTCTTG GGTCTCCAAG AAGTCTGTCC ACAGACTTCT GCCCTGGCTC TTCCCCATCT AGGCCTGGGC AGGAACATAT ATTATTTATT TAAGCAATTA CTTTTCATGT TGGGGTGGGG ACGGAGGGGA AAGGGAAGCC TGGGTTTTTG TACAAAAATG TGAGAAACCT TTGTGAGACA GAGAACAGGG AATTAAATGT GTCATACATA TCCACTTGAG GGCGATTTGT CTGAGAGCTG GGGCTGGATG CTTGGGTAAC TGGGGCAGGG CAGGTGGAGG GGAGACCTCC ATTCAGGTGG AGGTCCCGAG TGGGCGGGGC AGCGACTGGG AGATGGGTCG GTCACCCAGA CAGCTCTGTG GAGGCAGGGT CTGAGCCTTG CCTGGGGCCC CGCACTGCAT AGGGCCGTTT GTTTGTTTTT TGAGATGGAG TCTCGCTCTG

TTGCCTAGGC TGGAGTGCAG TGAGGCAATC TAAGGTCACT GCAACCTCCA CCTCCCGGGT TCAAGCAATT CTCCTGCCTC AGCCTCCCGA TTAGCTGGGA TCACAGGTGT GCACCACCAT GCCCAGCTAA TTATTTATTT CTTTTGTATT TTTAGTAGAG ACAGGGTTTC ACCATGTTGG CCAGGCTGGT TTCGAACTCC TGACCTCAGG TGATCCTCCT GCCTCGGCCT CCCAAAGTGC TGGGATTACA GGTGTGAGCC ACCACACCTG ACCCATAGGT CTTCAATAAA TATTTAATGG AAGGTTCCAC AAGTCACCCT GTGATCAACA GTACCCGTAT GGGACAAAGC TGCAAGGTCA AGATGGTTCA TTATGGCTGT GTTCACCATA GCAAACTGGA AACAATCTAG ATATCCAACA GTGAGGGTTA AGCAACATGG TGCATCTGTG GATAGAACGC CACCCAGCCG CCCGGAGCAG GGACTGTCAT TCAGGGAGOC TAAGGAGAGA GGCTTGCTTG GGATATAGAA AGATATCCTG ACATTGGCCA

GGCATGGTGG CTCACGCCTG TAATCCTGGC ACTTTGGGAG GACGAAGCGA GTGGATCACT GAAGTCCAAG AGTTTGAGAC CGGCCTGCGA GACATGGCAA AACCCTGTCT CAAAAAAGAA AGAATGATGT CCTGACATGA AACAGCAGGC TACAAAACCA CTGCATGCTG TGATCCCAAT TTTGTGTTTT TCTTTCTATA TATGGATTAA AACAAAAATC CTAAAGGGAA ATACGCCAAA ATGTTGACAA TGACTGTCTC CAGGTCAAAG GAGAGAGGTG GGATTGTGGG TGACTTTTAA TGTGTATGAT TGTCTGTATT TTACAGAATT TCTGCCATGA CTGTGTATTT TGCATGACAC ATTTTAAAAA TAATAAACAC TATTTTTAGA ATAACAGAAT ATCAGCCTCC TCCTCTCCAA AAATAAGCCC TCAGGAGGGG ACAAAGTTGA CCGCTGATTG AGCCTGTCAG GGCTGTGCAC-3' (SEQ ID NO: 12373)

Human Adenosine Al Receptor Nucleic Acid and Antisense Oligonucleotide Fragments

5'-ATGCCGCCCT CCATCTCAGC TTTCCAGGCC GCCTACATCG GCATCGAGGT GCTCATCGCC CTGGTCTCTG TGCCCGGGAA CGTGCTGGTG ATCTGGGCGG TGAAGGTGAA CCAGGCGCTG CGGGATGCCA CCTTCTGCTT CATCGTCTCG CTGGCGGTGG CTGATGTGGC CGTGGGTGCC CTGGTCATCC CCCTCGCCAT CCTCATCAAC ATTGGGCCAC AGACCTACTT CCACACCTGC CTCATGGTTG CCTGTCCGGT CCTCATCCTC ACCCAGAGCT CCATCCTGGC CCTGCTGGCA ATTGCTGTGG ACCGCTACCT CCGGGTCAAG ATCCCTCTCC GGTACAAGAT GGTGGTGACC CCCCGGAGGG CGGCGGTGGC CATAGCCGGC TGCTGGATCC TCTCCTTCGT GGTGGGACTG CCCCTATGT

TTGGCTGGAA CAATCTGAGT GCGGTGGAGC GGGCCTGGGC AGCCAACGGC AGCATGGGGG AGCCCGTGAT CAAGTGCGAG TTCGAGAAGG TCATCAGCAT GGAGTACATG GTCTACTTCA ACTTCTTTGT GTGGGTGCTG CCCCCGCTTC TCCTCATGGT CCTCATCTAC CTGGAGGTCT TCTACCTAAT CCGCAAGCAG CTCAACAAGA AGGTGTCGGC CTCCTCCGGC GACCCGCAGA AGTACTATGG GAAGGAGCTG AAGATCGCCA AGTCGCTGGC CCTCATCCTC TTCCTCTTTG CCCTCAGCTG GCTGCCTTTG CACATCCTCA ACTGCATCAC CCTCTTCTGC CCGTCCTGCC ACAAGCCCAG CATCCTTACC TACATTGCCA TCTTCCTCAC GCACGGCAAC TCGGCCATGA ACCCCATTGT CTATGCCTTC CGCATCCAGA AGTTCCGCGT CACCTTCCTT AAGATTTGGA ATGACCATTT CCGCTGCCAG CCTGCACCTC CCATTGACGA GGATCTCCCA GAAGAGAGGC

CTGATGACTA G ATGAGTGTCA GAAGTGTGAA GGGTGCCTGT TCTGAATCCC AGAGCCTCCT CTCCCTCTGT GAGGCTGGCA GGTGAGGAAG GGTTTAACCT CACTGGAAGG AATCCCTGGA GCTAGCGGCT GCTGAAGGCG TCGAGGTGTG GGGGCACTTG GACAGAACAG TCAGGCAGCC GGGAGCTCTG CCAGCTTTGG TGACCTTGGG CCGGGCTGGG AGCGCTGCGG CGGGAGCCGG AGGACTATGA GCTGCCGCGC GTTGTCCAGA GCCCAGCCCA GCCCTACGCG CGCGGCCCGG AGCTCTGTTC CCTGGAACTT TGGGCACTGC CTCTGGGACC CCTGCCGGCC AGCAGGCAGG ATGGTGCTTG CCTCGTGCCC CTTGGTGCCC GTCTGCTGAT GTGCCCAGCC TGTGCCCGCC ATGCCGCCCT CCATCTCAGC TTTCCAGGCC GCCTACATCG GCATCGAGGT GCTCATCGCC CTGGTCTCTG TGCCCGGGAA CGTGCTGGTG ATCTGGGCGG

TGAAGGTGAA CCAGGCGCTG CGGGATGCCA CCTTCTGCTT CATCGTGTCG CTGGCGGTGG CTGATGTGGC CGTGGGTGCC CTGGTCATCC CCCTCGCCAT CCTCATCAAC ATTGGGCCAC AGACCTACTT CCACACCTGC CTCATGGTTG CCTGTCCGGT CCTCATCCTC ACCCAGAGCT CCATCCTGGC CCTGCTGGCA ATTGCTGTGG ACCGCTACCT CCGGGTCAAG ATCCCTCTCC GGTACAAGAT GGTGGTGACC CCCCGGAGGG CGGCGGTGGC CATAGCCGGC TGCTGGATCC TCTCCTTCGT GGTGGGACTG ACCCCTATGT TTGGCTGGAA CAATCTGAGT GCGGTGGAGC GGGCCTGGGC AGCCAACGGC AGCATGGGGG AGCCCGTGAT CAAGTGCGAG TTCGAGAAGG TCATCAGCAT GGAGTACATG GTCTACTTCA ACTTCTTTGT GTGGGTGCTG CCCCCGCTTC TCCTCATGGT CCTCATCTAC CTGGAGGTCT TCTACCTAAT CCGCAAGCAG CTCAACAAGA AGGTGTCGGC CTCCTCCGGC GACCCGCAGA AGTACTATGG GAAGGAGCTG AAGATCGCCA AGTCGCTGGC CCTCATCCTC TTCCTCTTTG CCCTCAGCTG GCTGCCTTTG CACATCCTCA ACTGCATCAC CCTCTTCTGC CCGTCCTGCC ACAAGCCCAG CATCCTTACC TACATTGCCA TCTTCCTCAC GCACGGCAAC TCGGCCATGA ACCCCATTGT CTATGCCTTC CGCATCCAGA AGTTCCGCGT CACCTTCCTT AAGATTTGGA ATGACCATTT CCGCTGCCAG CCTGCACCTC CCATTGACGA GGATCTCCCA GAAGAGAGGC CTGATGACTA GACCCCGCCT TCCGCTCCCA CCAGCCCACA TCCAGTGGGG TCTCAGTCCA GTCCTCACAT GCCCGCTGTC CCAGGGGTCT CCCTGAGCCT GCCCCAGCTG

GGCTGTTGGC TGGGGGCATG GGGGAGGCTC TGAAGAGATA CCCACAGAGT GTGGTCCCTC CACTAGGAGT TAACTACCCT ACACCTCTGG GCCCTGCAGG AGGCCTGGGA GGGCAAGGGT CCTACGGAGG GACCAGGTGT CTAGAGGCAA CAGTGTTCTG AGCCCCCACC TGCCTGACCA TCCCATGAGC AGTCCAGCGC TTCAGGGCTG GGCAGGTCCT GGGGAGGCTG AGACTGCAGA GGAGCCACCT GGGCTGGGAG AAGGTGCTTG GGCTTCTGCG GTGAGGCAGG GGAGTCTGCT TGTCTTAGAT GTTGGTGGTG CAGCCCCAGG ACCAAGCTTA AGGAGAGGAG AGCATCTGCT CTGAGACGGA TGGAAGGAGA GAGGTTGAGG ATGCACTGGC CTGTTCTGTA GGAGAGACTG GCCAGAGGCA GCTAAGGGGC AGGAATCAAG GAGCCTCCGT TCCCACCTCT GAGGACTCTG GACCCCAGGC CATACCAGGT GCTAGGGTGC CTGCTCTCCT TGCCCTGGGC

CAGCCCAGGA TTGTACGTGG GAGAGGCAGA AAGGGTAGGT TCAGTAATCA TTTCTGATGA TTTGCTGGAG TGCTGGCTCC ACGCCCTGGG GAGTGAGCTT GGTGCGGTAG GTGCTGGCCT CAAACAGCCA CGAGGTGGTA GCTCTGAGCC CTCCTTCTTG CCCTGAGCTT TCCGGGGAGG AGCCTGGAGT GTAATTACCT GTCATCTGGG CCACCAGCTC CACTGGCCCC CGTTGCCGGG CCTGGACTGT CCTAGGTGAC CCCATCTCTG CTGCTTCTGG GCCTGATGGA GAGGAGAACA CTAGACATGC CAACTCGGGA GCATTCTGCC TGCCTGGGAA CGGGGTGGAC GAGGGAGTGT CTGTAAGGAC TCAGTGTTGA CTGTAGGCGC CCCTGGGGTG GGTTTAGCAG GCTGCAGCAG GCAGAGGAGG AGTACCCCCC TGAGAGCATG TGGGGGAAGG CCTTGCTGTC ATGTGAATCC CTCAATACCC CTAGTATCTG GCTGGGTTTT CAGGGGCTTT GGAAGCTCTG TTGCAGGTGT

CCGGGGGTCT AGGACTTTAG GGATCTGGGA TCTGGGGAAG GACCAACCCA TGCCCTGCCA AGCCTGGAGC CCCTGTGTTG GGGGGCAAGG TGGGGGAGCC TGGAGCCCCT GTGTGGGAGG GCGAGGCGGG GGAGCCTGGA GCCCCTGTGT GGGAGGOCGA GGCGGGGGAT CCTGGAGCCC CTGTGTCGGG GGGCGAGGGA GGGGAGGTGG CCGTCGGTTG ACCTTCTGAA CATGAGTGTC AACTCCAGGA CTTGCTTCCA AGCCCTTCCC TCTGTTGGAA ATTGGGTGTG CCCTGGCTCC CAAGGGAGGC CCATGTGACT AATAAAAAAC TGTGAACCCT CGCATTTGTG TTTTAATAAA AGAATCTGGA AGATAAATAG TCTTGAAGAG AGACAAAGGA AGGAAAATTT AAATCCTTAG ATTCAAGCAG AAGAATTCCA TGTGGAAGGT TTGGGTTGTT GTTGTTGTTG TTTGGTGTGT TTTTTGTTTT TTTGTTTTTT TGTTTTTTTT TGAGATGGAG

TCTCGCTGTG TTACCGGGAG CGACAGAGCC GCACGGCCGA GTCGAGTCCC AGCCAGCTAC CATCCCTCTG GAGCTTACCG GCCGGCCTTG GCTTCCCCAG GAATCCCTGG AGCTAGCGGC TGCTGAAGGC GTCGAGGTGT GGGGGCACTT GGACAGAACA GTCAGGCAGC CGGGAGCTCT GCCAGCTTTG GTGACCTTGG GTGCTTGCCT CGTGCCCCTT GGTGCCCGTC TGCTGATGTG CCCAGCCTGT GCCCGCCATG CCGCCCTCCA TCTCAGCTTT CCAGGCCGCC TACATCGGCA TCGAGGTGCT CATCGCCCTG GTCTCTGTGC CCGGGAACGT GCTGGTGATC TGGGCGGTGA AGGTGAACCA GGCGCTGCGG GATGCCACCT TCTGCTTCAT CGTGTCGCTG GCGGTGGCTG ATGTGGCCGT GGGTGCCCTG GTCATCCCCC TCGCCATCCT CATCAACATT GGGCCACAGA CCTACTTCCA CACCTGCCTC ATGGTTGCCT GTCCGGTCCT CATCCTCACC CAGAGCTCCA TCCTGGCCCT

GCTGGCAATT GCTGTGGACC GCTACCTCCG GGTCAAGATC CCTCTCCGGT ACAAGATGGT GGTGACCCCC CGGAGGGCGG CGGTGGCCAT AGCCGGCTGC TGGATCCTCT CCTTCGTGGT GGGACTGACC CCTATGTTTG GCTGGAACAA TCTGAGTGCG GTGGAGCGGG CCTGGGCAGC CAACGGCAGC ATGGGGGAGC CCGTGATCAA GTGCGAGTTC GAGAAGGTCA TCAGCATGGA GTACATGGTC TACTTCAACT TCTTTGTGTG GGTGCTGCCC CCGCTTCTCC TCATGGTCCT CATCTACCTG GAGGTCTTCT ACCTAATCCG CAAGCAGCTC AACAAGAAGG TGTCGGCCTC CTCCGGCGAC CCGCAGAAGT ACTATGGGAA GGAGCTGAAG ATCGCCAAGT CGCTGGCCCT CATCCTCTTC CTCTTTGCCC TCAGCTGGCT GCCTTTGCAC ATCCTCAACT GCATCACCCT CTTCTGCCCG TCCTGCCACA AGCCCAGCAT CCTTACCTAC ATTGCCATCT TCCTCACGCA CGGCAACTCG

GCCATGAACC CCATTGTCTA TGCCTTCCGC ATCCAGAAGT TCCGCGTCAC CTTCCTTAAG ATTTGGAATG ACCATTTCCG CTGCCAGCCT GCACCTCCCA TTGACGAGGA TCTCCCAGAA GAGAGGCCTG ATGACTAGAC CCCGCCTTCC GCTCCCACCG CCCACATCCA GTGGGGTCTC AGTCCAGTCC TCACATGCCC GCTGTCCCAG GGGTCTCCCT GAGCCTGCCC CAGCTGGGCT GTTGGCTGGG GGCATGGGGG AGGCTCTGAA GAGATACCCA CAGAGTGTGG TCCCTCCACT AGGAGTTAAC TACCCTACAC CTCTGGGCCC TGCAGGAGGC CTGGGAGGGC AAGGGTCCTA CGGAGGGACC AGGTGTCTAG AGGCAACAGT GTTCTGAGCC CCGACCTGCC TGACCATCCC ATGAGCAGTC CAGAGCTTCA GGGCTGGGCA GGTCCTGGGG AGGCTGAGAC TGCAGAGGAG CCACCTGGGC TGGGAGAAGG TGCTTGGGCT TCTGCGGTGA GGCAGGGGAG TCTGCTTGTC

TTAGATGTTG GTGGTGCAGC CCCAGGACCA AGCTTAAGGA GAGGAGAGCA TCTGCTCTGA GACGGATGGA AGGAGAGAGG TTGAGGATGC ACTGGCCTGT TCTGTAGGAG AGACTGGCCA GA GAT GGA GGG CGG CAT GGC GGG G CGG GTC GCC GG GGC GGG CBC BGG C GGC GGG CBC GC GGC CTG G GGB GGG CGG C GBT GGB GGG GG CTG GGC GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC ATGCCGCCCT CCATCTCAGC TTTCCAGGCC GCCTACATCG GCATCGAGGT GCTCATCGCC CTGGTCTCTG TGCCCGGGAA CGTGCTGGTG ATCTGGGCGG TGAAGGTGAA CCAGGCGCTG CGGGATGCCA CCTTCTGCTT CATCGTCTCG CTGGCGGTGG CTGATGTGGC CGTGGGTGCC CTGGTCATCC CCCTCGCCAT CCTCATCAAC ATTGGGCCAC AGACCTACTT CCACACCTGC CTCATGGTTG

CCTGTCCGGT CCTCATCCTC ACCCAGAGCT CCATCCTGGC CCTGCTGGCA ATTGCTGTGG ACCGCTACCT CCGGGTCAAG ATCCCTCTCC GGTACAAGAT GGTGGTGACC CCCCGGAGGG CGGCGGTGGC CATAGCCGGC TGCTGGATCC TCTCCTTCGT GGTGGGACTG ACCCCTATGT TTGGCTGGAA CAATCTGAGT GCGGTGGAGC GGGCCTGGGC AGCCAACGGC AGCATGGGGG AGCCCGTGAT CAAGTGCGAG TTCGAGAAGG TCATCAGCAT GGAGTACATG GTCTACTTCA ACTTCTTTGT GTGGGTGCTG CCCCCGCTTC TCCTCATGGT CCTCATCTAC CTGGAGGTCT TCTACCTAAT CCGCAAGCAG CTCAACAAGA AGGTGTCGGC CTCCTCCGGC GACCCGCAGA AGTACTATGG GAAGGAGCTG AAGATCGCCA AGTCGCTGGC CCTCATCCTC TTCCTCTTTG CCCTCAGCTG GCTGCCTTTG CACATCCTCA ACTGCATCAC CCTCTTCTGC CCGTCCTGCC ACAAGCCCAG

CATCCTTACC TACATTGCCA TCTTCCTCAC GCACGGCAAC TCGGCCATGA ACCCCATTGT CTATGCCTTC CGCATCCAGA AGTTCCGCGT CACCTTCCTT AAGATTTGGA ATGACCATTT CCGCTGCCAG CCTGCACCTC CCATTGACGA GGATCTCCCA GAAGAGAGGC CTGATGACTA G ATGAGTGTCA GAAGTGTGAA GGGTGCCTGT TCTGAATCCC AGAGCCTCCT CTCCCTCTGT GAGGCTGGCA GGTGAGGAAG GGTTTAACCT CACTGGAAGG AATCCCTGGA GCTAGCGGCT GCTGAAGGCG TCGAGGTGTG GGGGCACTTG GACAGAACAG TCAGGCAGCC GGGAGCTCTG CCAGCTTTGG TGACCTTGGG CCGGGCTGGG AGCGCTGCGG CGGGAGCCGG AGGACTATGA GCTGCCGCGC GTTGTCCAGA GCCCAGCCCA GCCCTACGCG CGCGGCCCGG AGCTCTGTTC CCTGGAACTT TGGGCACTGC CTCTGGGACC CCTGCCGGCC AGCAGGCAGG

ATGGTGCTTG CCTCGTGCCC CTTGGTGCCC GTCTGCTGAT GTGCCCAGCC TGTGCCCGCC ATGCCGCCCT CCATCTCAGC TTTCCAGGCC GCCTACATCG GCATCGAGGT GCTCATCGCC CTGGTCTCTG TGCCCGGGAA CGTGCTGGTG ATCTGGGCGG TGAAGGTGAA CCAGGCGCTG CGGGATGCCA CCTTCTGCTT CATCGTGTCG CTGGCGGTGG CTGATGTGGC CGTGGGTGCC CTGGTCATCC CCCTCGCCAT CCTCATCAAC ATTGGGCCAC AGACCTACTT CCACACCTGC CTCATGGTTG CCTGTCCGGT CCTCATCCTC ACCCAGAGCT CCATCCTGGC CCTGCTGGCA ATTGCTGTGG ACCGCTACCT CCGGGTCAAG ATCCCTCTCC GGTACAAGAT GGTGGTGACC CCCCGGAGGG CGGCGGTGGC CATAGCCGGC TGCTGGATCC TCTCCTTCGT GGTGGGACTG ACCCCTATGT TTGGCTGGAA CAATCTGAGT GCGGTGGAGC GGGCCTGGGC AGCCAACGGC AGCATGGGGG

AGCCCGTGAT CAAGTGCGAG TTCGAGAAGG TCATCAGCAT GGAGTACATG GTCTACTTCA ACTTCTTTGT GTGGGTGCTG CCCCCGCTTC TCCTCATGGT CCTCATCTAC CTGGAGGTCT TCTACCTAAT CCGCAAGCAG CTCAACAAGA AGGTGTCGGC CTCCTCCGGC GACCCGCAGA AGTACTATGG GAAGGAGCTG AAGATCGCCA AGTCGCTGGC CCTCATCCTC TTCCTCTTTG CCCTCAGCTG GCTGCCTTTG CACATCCTCA ACTGCATCAC CCTCTTCTGC CCGTCCTGCC ACAAGCCCAG CATCCTTACC TACATTGCCA TCTTCCTCAC GCACGGCAAC TCGGCCATGA ACCCCATTGT CTATGCCTTC CGCATCCAGA AGTTCCGCGT CACCTTCCTT AAGATTTGGA ATGACCATTT CCGCTGCCAG CCTGCACCTC CCATTGACGA GGATCTCCCA GAAGAGAGGC CTGATGACTA GACCCCGCCT TCCGCTCCCA CCAGCCCACA TCCAGTGGGG TCTCAGTCCA GTCCTCACAT

GCCCGCTGTC CCAGGGGTCT CCCTGAGCCT GCCCCAGCTG GGCTGTTGGC TGGGGGCATG GGGGAGGCTC TGAAGAGATA CCCACAGAGT GTGGTCCCTC CACTAGGAGT TAACTACCCT ACACCTCTGG GCCCTGCAGG AGGCCTGGGA GGGCAAGGGT CCTACGGAGG GACCAGGTGT CTAGAGGCAA CAGTGTTCTG AGCCCCCACC TGCCTGACCA TCCCATGAGC AGTCCAGCGC TTCAGGGCTG GGCAGGTCCT GGGGAGGCTG AGACTGCAGA GGAGCCACCT GGGCTGGGAG AAGGTGCTTG GGCTTCTGCG GTGAGGCAGG GGAGTCTGCT TGTCTTAGAT GTTGGTGGTG CAGCCCCAGG ACCAAGCTTA AGGAGAGGAG AGCATCTGCT CTGAGACGGA TGGAAGGAGA GAGGTTGAGG ATGCACTGGC CTGTTCTGTA GGAGAGACTG GCCAGAGGCA GCTAAGGGGC AGGAATCAAG GAGCCTCCGT TCCCACCTCT GAGGACTCTG

GACCCCAGGC CATACCAGGT GCTAGGGTGC CTGCTCTCCT TGCCCTGGGC CAGCCCAGGA TTGTACGTGG GAGAGGCAGA AAGGGTAGGT TCAGTAATCA TTTCTGATGA TTTGCTGGAG TGCTGGCTCC ACGCCCTGGG GAGTGAGCTT GGTGCGGTAG GTGCTGGCCT CAAACAGCCA CGAGGTGGTA GCTCTGAGCC CTCCTTCTTG CCCTGAGCTT TCCGGGGAGG AGCCTGGAGT GTAATTACCT GTCATCTGGG CCACCAGCTC CACTGGCCCC CGTTGCCGGG CCTGGACTGT CCTAGGTGAC CCCATCTCTG CTGCTTCTGG GCCTGATGGA GAGGAGAACA CTAGACATGC CAACTCGGGA GCATTCTGCC TGCCTGGGAA CGGGGTGGAC GAGGGAGTGT CTGTAAGGAC TCAGTGTTGA CTGTAGGCGC CCCTGGGGTG GGTTTAGCAG GCTGCAGCAG GCAGAGGAGG AGTACCCCCC TGAGAGCATG TGGGGGAAGG CCTTGCTGTC ATGTGAATCC CTCAATACCC

CTAGTATCTG GCTGGGTTTT CAGGGGCTTT GGAAGCTCTG TTGCAGGTGT CCGGGGGTCT AGGACTTTAG GGATCTGGGA TCTGGGGAAG GACCAACCCA TGCCCTGCCA AGCCTGGAGC CCCTGTGTTG GGGGGCAAGG TGGGGGAGCC TGGAGCCCCT GTGTGGGAGG GCGAGGCGGG GGAGCCTGGA GCCCCTGTGT GGGAGGGCGA GGCGGGGGAT CCTGGAGCCC CTGTGTCGGG GGGCGAGGGA GGGGAGGTGG CCGTCGGTTG ACCTTCTGAA CATGAGTGTC AACTCCAGGA CTTGCTTCCA AGCCCTTCCC TCTGTTGGAA ATTGGGTGTG CCCTGGCTCC CAAGGGAGGC CCATGTGACT AATAAAAAAC TGTGAACCCT CGCATTTGTG TTTTAATAAA AGAATCTGGA AGATAAATAG TCTTGAAGAG AGACAAAGGA AGGAAAATTT AAATCCTTAG ATTCAAGCAG AAGAATTCCA TGTGGAAGGT TTGGGTTGTT GTTGTTGTTG TTTGGTGTGT TTTTTGTTTT

TTTGTTTTTT TGTTTTTTTT TGAGATGGAG TCTCGCTGTG TTACCGGGAG CGACAGAGCC GCACGGCCGA GTCGAGTCCC AGCCAGCTAC CATCCCTCTG GAGCTTACCG GCCGGCCTTG GCTTCCCCAG GAATCCCTGG AGCTAGCGGC TGCTGAAGGC GTCGAGGTGT GGGGGCACTT GGACAGAACA GTCAGGCAGC CGGGAGCTCT GCCAGCTTTG GTGACCTTGG GTGCTTGCCT CGTGCCCCTT GGTGCCCGTC TGCTGATGTG CCCAGCCTGT GCCCGCCATG CCGCCCTCCA TCTCAGCTTT CCAGGCCGCC TACATCGGCA TCGAGGTGCT CATCGCCCTG GTCTCTGTGC CCGGGAACGT GCTGGTGATC TGGGCGGTGA AGGTGAACCA GGCGCTGCGG GATGCCACCT TCTGCTTCAT CGTGTCGCTG GCGGTGGCTG ATGTGGCCGT GGGTGCCCTG GTCATCCCCC TCGCCATCCT CATCAACATT GGGCCACAGA CCTACTTCCA CACCTGCCTC ATGGTTGCCT GTCCGGTCCT

CATCCTCACC CAGAGCTCCA TCCTGGCCCT GCTGGCAATT GCTGTGGACC GCTACCTCCG GGTCAAGATC CCTCTCCGGT ACAAGATGGT GGTGACCCCC CGGAGGGCGG CGGTGGCCAT AGCCGGCTGC TGGATCCTCT CCTTCGTGGT GGGACTGACC CCTATGTTTG GCTGGAACAA TCTGAGTGCG GTGGAGCGGG CCTGGGCAGC CAACGGCAGC ATGGGGGAGC CCGTGATCAA GTGCGAGTTC GAGAAGGTCA TCAGCATGGA GTACATGGTC TACTTCAACT TCTTTGTGTG GGTGCTGCCC CCGCTTCTCC TCATGGTCCT CATCTACCTG GAGGTCTTCT ACCTAATCCG CAAGCAGCTC AACAAGAAGG TGTCGGCCTC CTCCGGCGAC CCGCAGAAGT ACTATGGGAA GGAGCTGAAG ATCGCCAAGT CGCTGGCCCT CATCCTCTTC CTCTTTGCCC TCAGCTGGCT GCCTTTGCAC ATCCTCAACT GCATCACCCT CTTCTGCCCG TCCTGCCACA AGCCCAGCAT CCTTACCTAC

ATTGCCATCT TCCTCACGCA CGGCAACTCG GCCATGAACC CCATTGTCTA TGCCTTCCGC ATCCAGAAGT TCCGCGTCAC CTTCCTTAAG ATTTGGAATG ACCATTTCCG CTGCCAGCCT GCACCTCCCA TTGACGAGGA TCTCCCAGAA GAGAGGCCTG ATGACTAGAC CCCGCCTTCC GCTCCCACCG CCCACATCCA GTGGGGTCTC AGTCCAGTCC TCACATGCCC GCTGTCCCAG GGGTCTCCCT GAGCCTGCCC CAGCTGGGCT GTTGGCTGGG GGCATGGGGG AGGCTCTGAA GAGATACCCA CAGAGTGTGG TCCCTCCACT AGGAGTTAAC TACCCTACAC CTCTGGGCCC TGCAGGAGGC CTGGGAGGGC AAGGGTCCTA CGGAGGGACC AGGTGTCTAG AGGCAACAGT GTTCTGAGCC CCCACCTGCC TGACCATCCC ATGAGCAGTC CAGAGCTTCA GGGCTGGGCA GGTCCTGGGG AGGCTGAGAC TGCAGAGGAG CCACCTGGGC TGGGAGAAGG TGCTTGGGCT

TCTGCGGTGA GGCAGGGGAG TCTGCTTGTC TTAGATGTTG GTGGTGCAGC CCCAGGACCA AGCTTAAGGA GAGGAGAGCA TCTGCTCTGA GACGGATGGA AGGAGAGAGG TTGAGGATGC ACTGGCCTGT TCTGTAGGAG AGACTGGCCA GA -3'(FRAG.NO:_)(SEQNO:3005)

S'-CGCATTTGTG TTTTAATAAA AGAATCTGGA AGATAAATAG TCTTGAAGAG AGACAAAGGA AGGAAAATTT AAATCCTTAG ATTCAAGCAG AAGAATTCCA TGTGGAAGGT TTGGGTTGTT GTTGTTGTTG TTTGGTGTGT TTTTTGTTTT TTTGTTTTTT TGTTTTTTTT TGAGATGGAG TCTCGCTGTG TTACCGGGAG CGACAGAGCC GCACGGCCGA GTCGAGTCCC AGCCAGCTAC CATCCCTCTG GAGCTTACCG GCCGGCCTTG GCTTCCCCAG GAATCCCTGG AGCTAGCGGC TGCTGAAGGC GTCGAGGTGT

GGGGGCACTT GGACAGAACA GTCAGGCAGC CGGGAGCTCT GCCAGCTTTG GTGACCTTGG GTGCTTGCCT CGTGCCCCTT GGTGCCCGTC TGCTGATGTG CCCAGCCTGT GCCCGCCATG CCGCCCTCCA TCTCAGCTTT CCAGGCCGCC TACATCGGCA TCGAGGTGCT CATCGCCCTG GTCTCTGTGC CCGGGAACGT GCTGGTGATC TGGGCGGTGA AGGTGAACCA GGCGCTGCGG GATGCCACCT TCTGCTTCAT CGTGTCGCTG GCGGTGGCTG ATGTGGCCGT GGGTGCCCTG GTCATCCCCC TCGCCATCCT CATCAACATT GGGCCACAGA CCTACTTCCA CACCTGCCTC ATGGTTGCCT GTCCGGTCCT CATCCTCACC CAGAGCTCCA TCCTGGCCCT GCTGGCAATT GCTGTGGACC GCTACCTCCG GGTCAAGATC CCTCTCCGGT ACAAGATGGT GGTGACCCCC CGGAGGGCGG CGGTGGCCAT AGCCGGCTGC TGGATCCTCT CCTTCGTGGT GGGACTGACC CCTATGTTTG GCTGGAACAA TCTGAGTGCG GTGGAGCGGG CCTGGGCAGC CAACGGCAGC ATGGGGGAGC CCGTGATCAA GTGCGAGTTC GAGAAGGTCA TCAGCATGGA GTACATGGTC TACTTCAACT TCTTTGTGTG GGTGCTGCCC CCGCTTCTCC TCATGGTCCT CATCTACCTG GAGGTCTTCT ACCTAATCCG CAAGCAGCTC AACAAGAAGG TGTCGGCCTC CTCCGGCGAC CCGCAGAAGT ACTATGGGAA GGAGCTGAAG ATCGCCAAGT CGCTGGCCCT CATCCTCTTC CTCTTTGCCC TCAGCTGGCT GCCTTTGCAC ATCCTCAACT GCATCACCCT CTTCTGCCCG TCCTGCCACA AGCCCAGCAT CCTTACCTAC ATTGCCATCT TCCTCACGCA CGGCAACTCG GCCATGAACC CCATTGTCTA

TGCCTTCCGC ATCCAGAAGT TCCGCGTCAC CTTCCTTAAG ATTTGGAATG ACCATTTCCG CTGCCAGCCT GCACCTCCCA TTGACGAGGA TCTCCCAGAA GAGAGGCCTG ATGACTAGAC CCCGCCTTCC GCTCCCACCG CCCACATCCA GTGGGGTCTC AGTCCAGTCC TCACATGCCC GCTGTCCCAG GGGTCTCCCT GAGCCTGCCC CAGCTGGGCT GTTGGCTGGG GGCATGGGGG AGGCTCTGAA GAGATACCCA CAGAGTGTGG TCCCTCCACT AGGAGTTAAC TACCCTACAC CTCTGGGCCC TGCAGGAGGC CTGGGAGGGC AAGGGTCCTA CGGAGGGACC AGGTGTCTAG AGGCAACAGT GTTCTGAGCC CCCACCTGCC TGACCATCCC ATGAGCAGTC CAGAGCTTCA GGGCTGGGCA GGTCCTGGGG AGGCTGAGAC TGCAGAGGAG CCACCTGGGC TGGGAGAAGG TGCTTGGGCT TCTGCGGTGA GGCAGGGGAG TCTGCTTGTC TTAGATGTTG GTGGTGCAGC

CCCAGGACCA AGCTTAAGGA GAGGAGAGCA TCTGCTCTGA GACGGATGGA AGGAGAGAGG TTGAGGATGC ACTGGCCTGT TCTGTAGGAG AGACTGGCCA GA -3' (FRAG NO _J(SEQ ID NO 11803)

5'- ATGAGTGTCA GAAGTGTGAA GGGTGCCTGT TCTGAATCCC AGAGCCTCCT CTCCCTCTGT GAGGCTGGCA GGTGAGGAAG GGTTTAACCT CACTGGAAGG AATCCCTGGA GCTAGCGGCT GCTGAAGGCG TCGAGGTGTG GGGGCACTTG GACAGAACAG TCAGGCAGCC GGGAGCTCTG CCAGCTTTGG TGACCTTGGG CCGGGCTGGG AGCGCTGCGG CGGGAGCCGG AGGACTATGA GCTGCCGCGC GTTGTCCAGA GCCCAGCCCA GCCCTACGCG CGCGGCCCGG AGCTCTGTTC CCTGGAACTT

TGGGCACTGC CTCTGGGACC CCTGCCGGCC AGCAGGCAGG ATGGTGCTTG CCTCGTGCCC CTTGGTGCCC GTCTGCTGAT GTGCCCAGCC TGTGCCCGCC ATGCCGCCCT CCATCTCAGC TTTCCAGGCC GCCTACATCG GCATCGAGGT GCTCATCGCC CTGGTCTCTG TGCCCGGGAA CGTGCTGGTG ATCTGGGCGG TGAAGGTGAA CCAGGCGCTG CGGGATGCCA CCTTCTGCTT CATCGTGTCG CTGGCGGTGG CTGATGTGGC CGTGGGTGCC CTGGTCATCC CCCTCGCCAT CCTCATCAAC ATTGGGCCAC AGACCTACTT CCACACCTGC CTCATGGTTG CCTGTCCGGT CCTCATCCTC ACCCAGAGCT CCATCCTGGC CCTGCTGGCA ATTGCTGTGG ACCGCTACCT CCGGGTCAAG ATCCCTCTCC GGTACAAGAT GGTGGTGACC CCCCGGAGGG CGGCGGTGGC CATAGCCGGC TGCTGGATCC TCTCCTTCGT GGTGGGACTG ACCCCTATGT TTGGCTGGAA CAATCTGAGT

GCGGTGGAGC GGGCCTGGGC AGCCAACGGC AGCATGGGGG AGCCCGTGAT CAAGTGCGAG TTCGAGAAGG TCATCAGCAT GGAGTACATG GTCTACTTCA ACTTCTTTGT GTGGGTGCTG CCCCCGCTTC TCCTCATGGT CCTCATCTAC CTGGAGGTCT TCTACCTAAT CCGCAAGCAG CTCAACAAGA AGGTGTCGGC CTCCTCCGGC GACCCGCAGA AGTACTATGG GAAGGAGCTG AAGATCGCCA AGTCGCTGGC CCTCATCCTC TTCCTCTTTG CCCTCAGCTG GCTGCCTTTG CACATCCTCA ACTGCATCAC CCTCTTCTGC CCGTCCTGCC ACAAGCCCAG CATCCTTACC TACATTGCCA TCTTCCTCAC GCACGGCAAC TCGGCCATGA ACCCCATTGT CTATGCCTTC CGCATCCAGA AGTTCCGCGT CACCTTCCTT AAGATTTGGA ATGACCATTT CCGCTGCCAG CCTGCACCTC CCATTGACGA GGATCTCCCA GAAGAGAGGC CTGATGACTA GACCCCGCCT TCCGCTCCCA

CCAGCCCACA TCCAGTGGGG TCTCAGTCCA GTCCTCACAT GCCCGCTGTC CCAGGGGTCT CCCTGAGCCT GCCCCAGCTG GGCTGTTGGC TGGGGGCATG GGGGAGGCTC TGAAGAGATA CCCACAGAGT GTGGTCCCTC CACTAGGAGT TAACTACCCT ACACCTCTGG GCCCTGCAGG AGGCCTGGGA GGGCAAGGGT CCTACGGAGG GACCAGGTGT CTAGAGGCAA CAGTGTTCTG AGCCCCCACC TGCCTGACCA TCCCATGAGC AGTCCAGCGC TTCAGGGCTG GGCAGGTCCT GGGGAGGCTG AGACTGCAGA GGAGCCACCT GGGCTGGGAG AAGGTGCTTG GGCTTCTGCG GTGAGGCAGG GGAGTCTGCT TGTCTTAGAT GTTGGTGGTG CAGCCCCAGG ACCAAGCTTA AGGAGAGGAG AGCATCTGCT CTGAGACGGA TGGAAGGAGA GAGGTTGAGG ATGCACTGGC CTGTTCTGTA GGAGAGACTG GCCAGAGGCA GCTAAGGGGC AGGAATCAAG

GAGCCTCCGT TCCCACCTCT GAGGACTCTG GACCCCAGGC CATACCAGGT GCTAGGGTGC CTGCTCTCCT TGCCCTGGGC CAGCCCAGGA TTGTACGTGG GAGAGGCAGA AAGGGTAGGT TCAGTAATCA TTTCTGATGA TTTGCTGGAG TGCTGGCTCC ACGCCCTGGG GAGTGAGCTT GGTGCGGTAG GTGCTGGCCT CAAACAGCCA CGAGGTGGTA GCTCTGAGCC CTCCTTCTTG CCCTGAGCTT TCCGGGGAGG AGCCTGGAGT GTAATTACCT GTCATCTGGG CCACCAGCTC CACTGGCCCC CGTTGCCGGG CCTGGACTGT CCTAGGTGAC CCCATCTCTG CTGCTTCTGG GCCTGATGGA GAGGAGAACA CTAGACATGC CAACTCGGGA GCATTCTGCC TGCCTGGGAA CGGGGTGGAC GAGGGAGTGT CTGTAAGGAC TCAGTGTTGA CTGTAGGCGC CCCTGGGGTG GGTTTAGCAG GCTGCAGCAG GCAGAGGAGG AGTACCCCCC TGAGAGCATG TGGGGGAAGG

CCTTGCTGTC ATGTGAATCC CTCAATACCC CTAGTATCTG GCTGGGTTTT CAGGGGCTTT GGAAGCTCTG TTGCAGGTGT CCGGGGGTCT AGGACTTTAG GGATCTGGGA TCTGGGGAAG GACCAACCCA TGCCCTGCCA AGCCTGGAGC CCCTGTGTTG GGGGGCAAGG TGGGGGAGCC TGGAGCCCCT GTGTGGGAGG GCGAGGCGGG GGAGCCTGGA GCCCCTGTGT GGGAGGGCGA GGCGGGGGAT CCTGGAGCCC CTGTGTCGGG GGGCGAGGGA GGGGAGGTGG CCGTCGGTTG ACCTTCTGAA CATGAGTGTC AACTCCAGGA CTTGCTTCCA AGCCCTTCCC TCTGTTGGAA ATTGGGTGTG CCCTGGCTCC CAAGGGAGGC CCATGTGACT AATAAAAAAC TGTGAACCCT - 3' (FRAG NO _ (SEQ ID NO 11802)

5'- ATGCCGCCCT CCATCTCAGC TTTCCAGGCC GCCTACATCG GCATCGAGGT GCTCATCGCC CTGGTCTCTG TGCCCGGGAA CGTGCTGGTG ATCTGGGCGG TGAAGGTGAA CCAGGCGCTG CGGGATGCCA CCTTCTGCTT CATCGTCTCG CTGGCGGTGG CTGATGTGGC CGTGGGTGCC CTGGTCATCC CCCTCGCCAT CCTCATCAAC ATTGGGCCAC AGACCTACTT CCACACCTGC CTCATGGTTG CCTGTCCGGT CCTCATCCTC ACCCAGAGCT CCATCCTGGC CCTGCTGGCA ATTGCTGTGG ACCGCTACCT CCGGGTCAAG ATCCCTCTCC GGTACAAGAT GGTGGTGACC CCCCGGAGGG CGGCGGTGGC CATAGCCGGC TGCTGGATCC TCTCCTTCGT GGTGGGACTG ACCCCTATGT TTGGCTGGAA CAATCTGAGT GCGGTGGAGC GGGCCTGGGC AGCCAACGGC AGCATGGGGG AGCCCGTGAT CAAGTGCGAG TTCGAGAAGG TCATCAGCAT

GGAGTACATG GTCTACTTCA ACTTCTTTGT GTGGGTGCTG CCCCCGCTTC TCCTCATGGT CCTCATCTAC CTGGAGGTCT TCTACCTAAT CCGCAAGCAG CTCAACAAGA AGGTGTCGGC CTCCTCCGGC GACCCGCAGA AGTACTATGG GAAGGAGCTG AAGATCGCCA AGTCGCTGGC CCTCATCCTC TTCCTCTTTG CCCTCAGCTG GCTGCCTTTG CACATCCTCA ACTGCATCAC CCTCTTCTGC CCGTCCTGCC ACAAGCCCAG CATCCTTACC TACATTGCCA TCTTCCTCAC GCACGGCAAC TCGGCCATGA ACCCCATTGT CTATGCCTTC CGCATCCAGA AGTTCCGCGT CACCTTCCTT AAGATTTGGA ATGACCATTT CCGCTGCCAG CCTGCACCTC CCATTGACGA GGATCTCCCA GAAGAGAGGC CTGATGACTA G-3' (FRAG NO _)(SEQ ID NO 11801)

5'-CGCATTTGTG TTTTAATAAA AGAATCTGGA AGATAAATAG TCTTGAAGAG AGACAAAGGA AGGAAAATTT AAATCCTTAG ATTCAAGCAG AAGAATTCCA TGTGGAAGGT TTGGGTTGTT GTTGTTGTTG TTTGGTGTGT TTTTTGTTTT TTTGTTTTTT TGTTTTTTTT TGAGATGGAG TCTCGCTGTG TTACCGGGAG CGACAGAGCC GCACGGCCGA GTCGAGTCCC AGCCAGCTAC CATCCCTCTG GAGCTTACCG GCCGGCCTTG GCTTCCCCAG GAATCCCTGG AGCTAGCGGC TGCTGAAGGC GTCGAGGTGT GGGGGCACTT GGACAGAACA GTCAGGCAGC CGGGAGCTCT GCCAGCTTTG GTGACCTTGG GTGCTTGCCT CGTGCCCCTT GGTGCCCGTC TGCTGATGTG CCCAGCCTGT GCCCGCCATG CCGCCCTCCA TCTCAGCTTT CCAGGCCGCC TACATCGGCA TCGAGGTGCT CATCGCCCTG GTCTCTGTGC CCGGGAACGT GCTGGTGATC TGGGCGGTGA

AGGTGAACCA GGCGCTGCGG GATGCCACCT TCTGCTTCAT CGTGTCGCTG GCGGTGGCTG ATGTGGCCGT GGGTGCCCTG GTCATCCCCC TCGCCATCCT CATCAACATT GGGCCACAGA CCTACTTCCA CACCTGCCTC ATGGTTGCCT GTCCGGTCCT CATCCTCACC CAGAGCTCCA TCCTGGCCCT GCTGGCAATT GCTGTGGACC GCTACCTCCG GGTCAAGATC CCTCTCCGGT ACAAGATGGT GGTGACCCCC CGGAGGGCGG CGGTGGCCAT AGCCGGCTGC TGGATCCTCT CCTTCGTGGT GGGACTGACC CCTATGTTTG GCTGGAACAA TCTGAGTGCG GTGGAGCGGG CCTGGGCAGC CAACGGCAGC ATGGGGGAGC CCGTGATCAA GTGCGAGTTC GAGAAGGTCA TCAGCATGGA GTACATGGTC TACTTCAACT TCTTTGTGTG GGTGCTGCCC CCGCTTCTCC TCATGGTCCT CATCTACCTG GAGGTCTTCT ACCTAATCCG CAAGCAGCTC AACAAGAAGG

TGTCGGCCTC CTCCGGCGAC CCGCAGAAGT ACTATGGGAA GGAGCTGAAG ATCGCCAAGT CGCTGGCCCT CATCCTCTTC CTCTTTGCCC TCAGCTGGCT GCCTTTGCAC ATCCTCAACT GCATCACCCT CTTCTGCCCG TCCTGCCACA AGCCCAGCAT CCTTACCTAC ATTGCCATCT TCCTCACGCA CGGCAACTCG GCCATGAACC CCATTGTCTA TGCCTTCCGC ATCCAGAAGT TCCGCGTCAC CTTCCTTAAG ATTTGGAATG ACCATTTCCG CTGCCAGCCT GCACCTCCCA TTGACGAGGA TCTCCCAGAA GAGAGGCCTG ATGACTAGAC CCCGCCTTCC GCTCCCACCG CCCACATCCA GTGGGGTCTC AGTCCAGTCC TCACATGCCC GCTGTCCCAG GGGTCTCCCT GAGCCTGCCC CAGCTGGGCT GTTGGCTGGG GGCATGGGGG AGGCTCTGAA GAGATACCCA CAGAGTGTGG TCCCTCCACT AGGAGTTAAC TACCCTACAC CTCTGGGCCC TGCAGGAGGC CTGGGAGGGC

AAGGGTCCTA CGGAGGGACC AGGTGTCTAG AGGCAACAGT GTTCTGAGCC CCCACCTGCC TGACCATCCC ATGAGCAGTC CAGAGCTTCA GGGCTGGGCA GGTCCTGGGG AGGCTGAGAC TGCAGAGGAG CCACCTGGGC TGGGAGAAGG TGCTTGGGCT TCTGCGGTGA GGCAGGGGAG TCTGCTTGTC TTAGATGTTG GTGGTGCAGC CCCAGGACCA AGCTTAAGGA GAGGAGAGCA TCTGCTCTGA GACGGATGGA AGGAGAGAGG TTGAGGATGC ACTGGCCTGT TCTGTAGGAG AGACTGGCCA GA -3' (FRAG NO _)(SEQ ID NO 11791) 5'-ATGAGTGTCA GAAGTGTGAA GGGTGCCTGT TCTGAATCCC AGAGCCTCCT CTCCCTCTGT GAGGCTGGCA GGTGAGGAAG GGTTTAACCT CACTGGAAGG

AATCCCTGGA GCTAGCGGCT GCTGAAGGCG TCGAGGTGTG GGGGCACTTG GACAGAACAG TCAGGCAGCC GGGAGCTCTG CCAGCTTTGG TGACCTTGGG CCGGGCTGGG AGCGCTGCGG CGGGAGCCGG AGGACTATGA GCTGCCGCGC GTTGTCCAGA GCCCAGCCCA GCCCTACGCG CGCGGCCCGG AGCTCTGTTC CCTGGAACTT TGGGCACTGC CTCTGGGACC CCTGCCGGCC AGCAGGCAGG ATGGTGCTTG CCTCGTGCCC CTTGGTGCCC GTCTGCTGAT GTGCCCAGCC TGTGCCCGCC ATGCCGCCCT CCATCTCAGC TTTCCAGGCC GCCTACATCG GCATCGAGGT GCTCATCGCC CTGGTCTCTG TGCCCGGGAA CGTGCTGGTG ATCTGGGCGG TGAAGGTGAA CCAGGCGCTG CGGGATGCCA CCTTCTGCTT CATCGTGTCG CTGGCGGTGG CTGATGTGGC CGTGGGTGCC CTGGTCATCC CCCTCGCCAT CCTCATCAAC ATTGGGCCAC AGACCTACTT

CCACACCTGC CTCATGGTTG CCTGTCCGGT CCTCATCCTC ACCCAGAGCT CCATCCTGGC CCTGCTGGCA ATTGCTGTGG ACCGCTACCT CCGGGTCAAG ATCCCTCTCC GGTACAAGAT GGTGGTGACC CCCCGGAGGG CGGCGGTGGC CATAGCCGGC TGCTGGATCC TCTCCTTCGT GGTGGGACTG ACCCCTATGT TTGGCTGGAA CAATCTGAGT GCGGTGGAGC GGGCCTGGGC AGCCAACGGC AGCATGGGGG AGCCCGTGAT CAAGTGCGAG TTCGAGAAGG TCATCAGCAT GGAGTACATG GTCTACTTCA ACTTCTTTGT GTGGGTGCTG CCCCCGCTTC TCCTCATGGT CCTCATCTAC CTGGAGGTCT TCTACCTAAT CCGCAAGCAG CTCAACAAGA AGGTGTCGGC CTCCTCCGGC GACCCGCAGA AGTACTATGG GAAGGAGCTG AAGATCGCCA AGTCGCTGGC CCTCATCCTC TTCCTCTTTG CCCTCAGCTG GCTGCCTTTG CACATCCTCA ACTGCATCAC CCTCTTCTGC

CCGTCCTGCC ACAAGCCCAG CATCCTTACC TACATTGCCA TCTTCCTCAC GCACGGCAAC TCGGCCATGA ACCCCATTGT CTATGCCTTC CGCATCCAGA AGTTCCGCGT CACCTTCCTT AAGATTTGGA ATGACCATTT CCGCTGCCAG CCTGCACCTC CCATTGACGA GGATCTCCCA GAAGAGAGGC CTGATGACTA GACCCCGCCT TCCGCTCCCA CCAGCCCACA TCCAGTGGGG TCTCAGTCCA GTCCTCACAT GCCCGCTGTC CCAGGGGTCT CCCTGAGCCT GCCCCAGCTG GGCTGTTGGC TGGGGGCATG GGGGAGGCTC TGAAGAGATA CCCACAGAGT GTGGTCCCTC CACTAGGAGT TAACTACCCT ACACCTCTGG GCCCTGCAGG AGGCCTGGGA GGGCAAGGGT CCTACGGAGG GACCAGGTGT CTAGAGGCAA CAGTGTTCTG AGCCCCCACC TGCCTGACCA TCCCATGAGC AGTCCAGCGC TTCAGGGCTG GGCAGGTCCT GGGGAGGCTG AGACTGCAGA GGAGCCACCT

GGGCTGGGAG AAGGTGCTTG GGCTTCTGCG GTGAGGCAGG GGAGTCTGCT TGTCTTAGAT GTTGGTGGTG CAGCCCCAGG ACCAAGCTTA AGGAGAGGAG AGCATCTGCT CTGAGACGGA TGGAAGGAGA GAGGTTGAGG ATGCACTGGC CTGTTCTGTA GGAGAGACTG GCCAGAGGCA GCTAAGGGGC AGGAATCAAG GAGCCTCCGT TCCCACCTCT GAGGACTCTG GACCCCAGGC CATACCAGGT GCTAGGGTGC CTGCTCTCCT TGCCCTGGGC CAGCCCAGGA TTGTACGTGG GAGAGGCAGA AAGGGTAGGT TCAGTAATCA TTTCTGATGA TTTGCTGGAG TGCTGGCTCC ACGCCCTGGG GAGTGAGCTT GGTGCGGTAG GTGCTGGCCT CAAACAGCCA CGAGGTGGTA GCTCTGAGCC CTCCTTCTTG CCCTGAGCTT TCCGGGGAGG AGCCTGGAGT GTAATTACCT GTCATCTGGG CCACCAGCTC CACTGGCCCC CGTTGCCGGG CCTGGACTGT

CCTAGGTGAC CCCATCTCTG CTGCTTCTGG GCCTGATGGA GAGGAGAACA CTAGACATGC CAACTCGGGA GCATTCTGCC TGCCTGGGAA CGGGGTGGAC GAGGGAGTGT CTGTAAGGAC TCAGTGTTGA CTGTAGGCGC CCCTGGGGTG GGTTTAGCAG GCTGCAGCAG GCAGAGGAGG AGTACCCCCC TGAGAGCATG TGGGGGAAGG CCTTGCTGTC ATGTGAATCC CTCAATACCC CTAGTATCTG GCTGGGTTTT CAGGGGCTTT GGAAGCTCTG TTGCAGGTGT CCGGGGGTCT AGGACTTTAG GGATCTGGGA TCTGGGGAAG GACCAACCCA TGCCCTGCCA AGCCTGGAGC CCCTGTGTTG GGGGGCAAGG TGGGGGAGCC TGGAGCCCCT GTGTGGGAGG GCGAGGCGGG GGAGCCTGGA GCCCCTGTGT GGGAGGGCGA GGCGGGGGAT CCTGGAGCCC CTGTGTCGGG GGGCGAGGGA GGGGAGGTGG CCGTCGGTTG ACCTTCTGAA

CATGAGTGTC AACTCCAGGA CTTGCTTCCA AGCCCTTCCC TCTGTTGGAA ATTGGGTGTG CCCTGGCTCC CAAGGGAGGC CCATGTGACT AATAAAAAAC TGTGAACCCT - 3' (FRAG NO _) (SEQ ID NO 11790)

5'-ATGCCGCCCT CCATCTCAGC TTTCCAGGCC GCCTACATCG GCATCGAGGT GCTCATCGCC CTGGTCTCTG TGCCCGGGAA CGTGCTGGTG ATCTGGGCGG TGAAGGTGAA CCAGGCGCTG CGGGATGCCA CCTTCTGCTT CATCGTCTCG CTGGCGGTGG CTGATGTGGC CGTGGGTGCC CTGGTCATCC CCCTCGCCAT CCTCATCAAC ATTGGGCCAC AGACCTACTT CCACACCTGC CTCATGGTTG CCTGTCCGGT CCTCATCCTC ACCCAGAGCT CCATCCTGGC CCTGCTGGCA ATTGCTGTGG ACCGCTACCT

CCGGGTCAAG ATCCCTCTCC GGTACAAGAT GGTGGTGACC CCCCGGAGGG CGGCGGTGGC CATAGCCGGC TGCTGGATCC TCTCCTTCGT GGTGGGACTG CCCCTATGT

TTGGCTGGAA CAATCTGAGT GCGGTGGAGC GGGCCTGGGC AGCCAACGGC AGCATGGGGG AGCCCGTGAT CAAGTGCGAG TTCGAGAAGG TCATCAGCAT

GGAGTACATG GTCTACTTCA ACTTCTTTGT GTGGGTGCTG CCCCCGCTTC TCCTCATGGT CCTCATCTAC CTGGAGGTCT TCTACCTAAT CCGCAAGCAG CTCAACAAGA AGGTGTCGGC CTCCTCCGGC GACCCGCAGA AGTACTATGG GAAGGAGCTG AAGATCGCCA AGTCGCTGGC CCTCATCCTC TTCCTCTTTG CCCTCAGCTG GCTGCCTTTG

CACATCCTCA ACTGCATCAC CCTCTTCTGC CCGTCCTGCC ACAAGCCCAG CATCCTTACC TACATTGCCA TCTTCCTCAC GCACGGCAAC TCGGCCATGA ACCCCATTGT

CTATGCCTTC CGCATCCAGA AGTTCCGCGT CACCTTCCTT AAGATTTGGA ATGACCATTT CCGCTGCCAG CCTGCACCTC CCATTGACGA GGATCTCCCA GAAGAGAGGC

CTGATGACTA G (FRAG NO _J (SEQ ID NO 12483)

5'-GAT GGA GGG CGG CAT GGC GGG-3' (FRAG NO 1657) (SEQ TD NO 11781) S'-G CGG GTC GCC GG-3' (FRAG NO 1658) (SEQ ID NO 11782)

5'-GGC GGG CBC BGG C-3' (FRAG NO 1659) (SEQ ID NO 11783)

5'-GGC GGG CBC-3' (FRAG NO 1660) (SEQ ID NO 11784)

5'-GC GGC CTG G-3' (FRAG NO 1661) (SEQ TD NO 11785)

5'-GGB GGG CGG C-3' (FRAG NO 1662) (SEQ TD NO 11786) 5'-GBT GGB GGG-3' (FRAG NO 1663) (SEQ ID NO 11787)

5'-GG CTG GGC-3' (FRAG NO 1664) (SEQ TD NO 11788)

5'-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 1) (SEQ ID NO 9380)

5'-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3'(FRAG 2) (SEQ ID NO 12)

5'-GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3'(FRAG 3)(SEQ TD NO 9382) 5'-GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 4)(SEQ ID NO 9383)

5'-C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 5) (SEQ ID NO 9384)

5'-CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 6) (SEQ ID NO 9385)

5'-TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 7) (SEQ ID NO 9386)

5'-G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 8) (SEQ ID NO 9387) 5'-GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 9) (SEQ ID NO 9388)

5'-AA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 10) (SEQ ID NO 9389)

5'-A AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 11) (SEQ ID NO 9390)

5'-AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 12) (SEQ TD NO 9391)

5'-GC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 13) (SEQ ID NO 9392) 5'-C TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 14) (SEQ TD NO 9393)

5'-TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 15) (SEQ ID NO 9394)

5'-GA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 16) (SEQ ID NO 9395)

5'-A GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 17) (SEQ ID NO 9396)

5'-GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 18) (SEQ ID NO 9397) 5'-AT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 19) (SEQ ID NO 9398)

5'-T GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 20) (SEQ LD NO 9399)

S'-GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 21) (SEQ ID NO 9400)

5'-GA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 22) (SEQ ID NO 9401)

5'-A GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 23) (SEQ ID NO 9402) 5'-GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 24) (SEQ TD NO 9403)

5'-GG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 25) (SEQ ID NO 9404)

5'-G CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 26) (SEQ ID NO 9405)

5'-CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 27) (SEQ DO NO 9406)

5'-GG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 28) (SEQ ID NO 9407) 5'-G CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 29) (SEQ TD NO 9408)

5'-CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 30) (SEQ TD NO 9409)

5'-AT GGC GGG CAC AGG CTG GGC-3' (FRAG 31) (SEQ ID NO 9410)

5'-T GGC GGG CAC AGG CTG GGC-3' (FRAG 32) (SEQ ID NO 9411)

5'-GGC GGG CAC AGG CTG GGC-3' (FRAG 33) (SEQ ID NO 9412) 5'-GC GGG CAC AGG CTG GGC-3' (FRAG 34) (SEQ ID NO 9413)

5'-C GGG CAC AGG CTG GGC-3' (FRAG 35) (SEQ ID NO 9414)

5'-GGG CAC AGG CTG GGC-3' (FRAG 36) (SEQ ID NO 9415)

S'-GG CAC AGG CTG GGC-3' (FRAG 37) (SEQ TD NO 9416)

5'-G CAC AGG CTG GGC-3' (FRAG 38) (SEQ ID NO 9417) 5'-CAC AGG CTG GGC-3' (FRAG 39) (SEQ ID NO 9418)

5'-AC AGG CTG GGC-3' (FRAG 40) (SEQ LD NO 9419)

5'-C AGG CTG GGC-3' (FRAG 41) (SEQ TD NO 9420)

5'-AGG CTG GGC-3' (FRAG 42) (SEQ ID NO 9421)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3'(FRAG 43)(SEQ ID NO 9422) 5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 44)(SEQ ID NO 9423)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 45)(SEQ ID NO 9424)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 46)(SEQ ID NO 9425)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 47)(SEQ TD NO 9426)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 48)(SEQ ID NO 9427) 5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 49) (SEQ ID NO 9428)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 50) (SEQ TD NO 9429)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 51) (SEQ ID NO 9430)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 52) (SEQ ID NO 9431)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 53) (SEQ ID NO 9432) 5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 54) (SEQ TD NO 9433)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 55) (SEQ ID NO 9434)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 56) (SEQ TD NO 9435)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC G-3'(FRAG 57) (SEQ ID NO 9436)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 58) (SEQ ID NO 9437) 5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GG -3' (FRAG 59) (SEQ ID NO 9438)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT G -3' (FRAG 60) (SEQ ID NO 9439)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT -3' (FRAG 61) (SEQ ID NO 9440)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG CA-3' (FRAG 62) (SEQ ID NO 9441)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG C-3' (FRAG 63) (SEQ LD NO 9442) 5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CGG -3' (FRAG 64) (SEQ LD NO 9443)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG CG -3' (FRAG 65) (SEQ TD NO 9444)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG C -3' (FRAG 66) (SEQ ID NO 9445)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GGG -3' (FRAG 67) (SEQ TD NO 9446)

5'-GGC GGC CTG GAA AGC TGA GAT GGA GG -3' (FRAG 68) (SEQ TD NO 9447) 5'-GGC GGC CTG GAA AGC TGA GAT GGA G -3' (FRAG 69) (SEQ ID NO 9448)

5'-GGC GGC CTG GAA AGC TGA GAT GGA -3' (FRAG 70) (SEQ ID NO 9449) 5'-GGC GGC CTG GAA AGC TGA GAT GG-3' (FRAG 71) (SEQ ID NO 9450) 5'-GGC GGC CTG GAA AGC TGA GAT G -3' (FRAG 72) (SEQ ID NO 9451) 5'-GGC GGC CTG GAA AGC TGA GAT -3' (FRAG 73) (SEQ ID NO 9452) 5'-GGC GGC CTG GAA AGC TGA GA-3' (FRAG 74) (SEQ ID NO 9453)

S'-GGC GGC CTG GAA AGC TGA G-3' (FRAG 75) (SEQ ID NO 9454) 5'-GGC GGC CTG GAA AGC TGA-3' (FRAG 76) (SEQ ID NO 9455) 5'-GGC GGC CTG GAA AGC TG-3' (FRAG 77) (SEQ ID NO 9456) 5'-GGC GGC CTG GAA AGC T-3' (FRAG 78) (SEQ TD NO 9457) 5'-GGC GGC CTG GAA AGC-3' (FRAG 79) (SEQ ID NO 9458)

S'-GGC GGC CTG GAA AG-3' (FRAG 80) (SEQ ID NO 9459) 5'-GGC GGC CTG GAA A-3' (FRAG 81) (SEQ TD NO 9460) 5'-GGC GGC CTG GAA-3' (FRAG 82) (SEQ TD NO 9461) 5'-GGC GGC CTG GA-3' (FRAG 83) (SEQ TD NO 9462) '-GGC GGC CTG G-3' (FRAG 84) (SEQ ID NO 9463) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 85) (SEQ ID NO 9464) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 86) (SEQ ID NO 9465) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 87) (SEQ ID NO 9466) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 88) (SEQ TD NO 9467) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 89) (SEQ LD NO 9468) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 90) (SEQ TD NO 9469) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG 3' (FRAG 91) (SEQ ID NO 9470) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 92) (SEQ TD NO 9471) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 93) (SEQ LD NO 9472) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 94) (SEQ ID NO 9473) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CA 3' (FRAG 95) (SEQ TD NO 9474) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 96) (SEQ ID NO 9475) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 97) (SEQ ID NO 9476) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 98) (SEQ TD NO 9477) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 99) (SEQ TD NO 9478) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 100) (SEQ TD NO 9479) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GG -3' (FRAG 101) (SEQ TD NO 9480) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT G -3' (FRAG 102) (SEQ ID NO 9481) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT -3' (FRAG 103) (SEQ ID NO 9482) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG CA-3' (FRAG 104) (SEQ ID NO 9483) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG C-3' (FRAG 105) (SEQ ID NO 9484) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CGG -3' (FRAG 106) (SEQ TD NO 9485) '-GC GGC CTG GAA AGC TGA GAT GGA GGG CG -3' (FRAG 107) (SEQ ID NO 9486) '-GC GGC CTG GAA AGC TGA GAT GGA GGG C -3' (FRAG 108) (SEQ TD NO 9487) '-GC GGC CTG GAA AGC TGA GAT GGA GGG -3' (FRAG 109) (SEQ ID NO 9488) '-GC GGC CTG GAA AGC TGA GAT GGA GG -3' (FRAG 110) (SEQ ID NO 9489) '-GC GGC CTG GAA AGC TGA GAT GGA G -3' (FRAG 111) (SEQ ID NO 9490) '-GC GGC CTG GAA AGC TGA GAT GGA -3' (FRAG 112) (SEQ ID NO 9491) '-GC GGC CTG GAA AGC TGA GAT GG -3' (FRAG 113) (SEQ ID NO 9492) '-GC GGC CTG GAA AGC TGA GAT G -3' (FRAG 114) (SEQ TD NO 9493) '-GC GGC CTG GAA AGC TGA GAT -3' (FRAG 115) (SEQ ID NO 9494) '-GC GGC CTG GAA AGC TGA GA-3' (FRAG 116) (SEQ ID NO 9495) '-GC GGC CTG GAA AGC TGA G-3' (FRAG 117) (SEQ ID NO 9496) '-GC GGC CTG GAA AGC TGA-3' (FRAG 118) (SEQ ID NO 9497) '-GC GGC CTG GAA AGC TG-3' (FRAG 119) (SEQ ID NO 9498) '-GC GGC CTG GAA AGC T-3' (FRAG 120) (SEQ ID NO 9499) '-GC GGC CTG GAA AGC-3' (FRAG 121) (SEQ ID NO 9500) '-GC GGC CTG GAA AG-3' (FRAG 122) (SEQ ID NO 9501) '-GC GGC CTG GAA A-3' (FRAG 123) (SEQ ID NO 9502) '-GC GGC CTG GAA-3' (FRAG 124) (SEQ ID NO 9503) '-GC GGC CTG GA-3' (FRAG 125) (SEQ ID NO 9504) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 126) (SEQ ID NO 9505) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 127) (SEQ TD NO 9506) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 128) (SEQ ID NO 9507) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 129) (SEQ TD NO 9508) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 130) (SEQ ID NO 9509) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 131) (SEQ ID NO 9510) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 132) (SEQ TD NO 9511) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 133) (SEQ ID NO 9512) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 134) (SEQ ID NO 9513) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 135) (SEQ ID NO 9514) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 136) (SEQ TD NO 9515) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 137) (SEQ TD NO 9516) ' C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 138) (SEQ ID NO 9517) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 139) (SEQ ID NO 9518) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 140) (SEQ ID NO 9519) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 141) (SEQ ID NO 9520) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GG -3' (FRAG 142) (SEQ ID NO 9521) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT G -3' (FRA 143) (SEQ TD NO 9522) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT -3' (FRAG 144) (SEQ ID NO 9523) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG CA-3' (FRAG 145) (SEQ ID NO 9524) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG C-3' (FRAG 146) (SEQ TD NO 9525) '-C GGC CTG GAA AGC TGA GAT GGA GGG CGG -3' (FRAG 147) (SEQ ID NO 9526) '-C GGC CTG GAA AGC TGA GAT GGA GGG CG -3' (FRAG 148) (SEQ ID NO 9527) '-C GGC CTG GAA AGC TGA GAT GGA GGG C -3' (FRAG 148) (SEQ ID NO 9528) '-C GGC CTG GAA AGC TGA GAT GGA GGG -3' (FRAG 150) (SEQ ID NO 9529) '-C GGC CTG GAA AGC TGA GAT GGA GG -3' (FRAG 151) (SEQ ID NO 9530) '-C GGC CTG GAA AGC TGA GAT GGA G -3' (FRAG 152) (SEQ ID NO 9531) '-C GGC CTG GAA AGC TGA GAT GGA -3' (FRAG 153) (SEQ ID NO 9532) '-C GGC CTG GAA AGC TGA GAT GG -3' (FRAG 154) (SEQ ID NO 9533) '-C GGC CTG GAA AGC TGA GAT G -3' (FRAG 155) (SEQ ID NO 9534) '-C GGC CTG GAA AGC TGA GAT -3' (FRAG 156) (SEQ ID NO 9535) '-C GGC CTG GAA AGC TGA GA-3' (FRAG 157) (SEQ ID NO 9536) '-C GGC CTG GAA AGC TGA G-3' (FRAG 158) (SEQ TD NO 9537) '-C GGC CTG GAA AGC TGA-3' (FRAG 159) (SEQ ID NO 9538) '-C GGC CTG GAA AGC TG-3' (FRAG 160) (SEQ ID NO 9539) '-C GGC CTG GAA AGC T-3' (FRAG 161) (SEQ ID NO 9540) '-C GGC CTG GAA AGC-3' (FRAG 162) (SEQ ID NO 9541) '-C GGC CTG GAA AG-3' (FRAG 163) (SEQ ID NO 9542) '-C GGC CTG GAA A-3' (FRAG 164) (SEQ ID NO 9543) '-C GGC CTG GAA-3' (FRAG 165) (SEQ ID NO 9544) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 166) (SEQ ID NO 9545) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 167) (SEQ TD NO 9546) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 168) (SEQ TD NO 9547) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 169) (SEQ TD NO 9548) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 170) (SEQ ID NO 9549) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 171) (SEQ TD NO 9550) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 172) (SEQ ID NO 9551) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 173) (SEQ LD NO 9552) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 174) (SEQ ID NO 9553) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 175) (SEQ ID NO 9554) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 176) (SEQ ID NO 9555) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 177) (SEQ ID NO 9556) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 178) (SEQ ID NO 9557) V GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 179) (SEQ TD NO 9558) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 180) (SEQ TD NO 9559) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 181) (SEQ ID NO 9560) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT GG -3' (FRAG 182) (SEQ ID NO 9561) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT G -3' (FRAG 183) (SEQ ID NO 9562) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CAT -3' (FRAG 184) (SEQ ID NO 9563) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG CA-3' (FRAG 185) (SEQ ID NO 9564) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG C-3' (FRAG 186) (SEQ ID NO 9565) '- GGC CTG GAA AGC TGA GAT GGA GGG CGG -3' (FRAG 187) (SEQ TD NO 9566) '- GGC CTG GAA AGC TGA GAT GGA GGG CG -3' (FRAG 188) (SEQ ID NO 9567) '- GGC CTG GAA AGC TGA GAT GGA GGG C -3' (FRAG 189) (SEQ ID NO 9568) '- GGC CTG GAA AGC TGA GAT GGA GGG -3' (FRAG 190) (SEQ ID NO 9569) '- GGC CTG GAA AGC TGA GAT GGA GG -3' (FRAG 191) (SEQ ID NO 9570) '- GGC CTG GAA AGC TGA GAT GGA G -3' (FRAG 192) (SEQ ID NO 9571) '- GGC CTG GAA AGC TGA GAT GGA -3' (FRAG 193) (SEQ ID NO 9572) '- GGC CTG GAA AGC TGA GAT GG -3' (FRAG 194) (SEQ TD NO 9573) '- GGC CTG GAA AGC TGA GAT G -3' (FRAG 195) (SEQ ID NO 9574) '- GGC CTG GAA AGC TGA GAT -3' (FRAG 196) (SEQ TD NO 9575) '- GGC CTG GAA AGC TGA GA-3' (FRAG 197) (SEQ ID NO 9576) '- GGC CTG GAA AGC TGA G-3' (FRAG 198) (SEQ ID NO 9577) '- GGC CTG GAA AGC TGA-3' (FRAG 199) (SEQ ID NO 9578) '- GGC CTG GAA AGC TG-3' (FRAG 200 (SEQ ID NO 9579) '- GGC CTG GAA AGC T-3' (FRAG 201) (SEQ ID NO 9580) '- GGC CTG GAA AGC-3' (FRAG 202) (SEQ ID NO 9581) '- GGC CTG GAA AG-3' (FRAG 203) (SEQ ID NO 9582) '- GGC CTG GAA A-3' (FRAG 204) (SEQ ID NO 9583) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 205) (SEQ TD NO 9584) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 206) (SEQ TD NO 9585) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 207) (SEQ ID NO 9586) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 208) (SEQ ID NO 9587) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 209) (SEQ TD NO 9588) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 210) (SEQ ID NO 9589) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 211) (SEQ ID NO 9590) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 212) (SEQ DO NO 9591) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 213) (SEQ TD NO 9592) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 214) (SEQ ID NO 9593) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 215) (SEQ ID NO 9594) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 216) (SEQ ID NO 9595) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 217) (SEQ ID NO 9596) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 218) (SEQ ID NO 9597) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 219) (SEQ ID NO 9598) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 220) (SEQ ID NO 9599) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT GG -3' (FRAG 221) (SEQ ID NO 9600) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT G -3' (FRAG 222) (SEQ TD NO 9601) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CAT -3' (FRAG 223) (SEQ ID NO 9602) '- GC CTG GAA AGC TGA GAT GGA GGG CGG CA-3' (FRAG 224) (SEQ ID NO 9603) '- GC CTG GAA AGC TGA GAT GGA GGG CGG C-3' (FRAG 225) (SEQ TD NO 9604) '- GC CTG GAA AGC TGA GAT GGA GGG CGG -3' (FRAG 226) (SEQ ID NO 9605) '- GC CTG GAA AGC TGA GAT GGA GGG CG -3' (FRAG 227) (SEQ ID NO 9606) '- GC CTG GAA AGC TGA GAT GGA GGG C -3' (FRAG 228) (SEQ ID NO 9607) '- GC CTG GAA AGC TGA GAT GGA GGG -3' (FRAG 229) (SEQ TD NO 9608) '- GC CTG GAA AGC TGA GAT GGA GG -3' (FRAG 230) (SEQ ID NO 9609) '- GC CTG GAA AGC TGA GAT GGA G -3' (FRAG 231) (SEQ ID NO 9610) '- GC CTG GAA AGC TGA GAT GGA -3' (FRAG 232) (SEQ ID NO 9611) '- GC CTG GAA AGC TGA GAT GG -3' (FRAG 233) (SEQ ID NO 9612) '- GC CTG GAA AGC TGA GAT G -3' (FRAG 234) (SEQ ID NO 9613) '- GC CTG GAA AGC TGA GAT -3' (FRAG 235) (SEQ TD NO 9614) '- GC CTG GAA AGC TGA GA-3' (FRAG 236) (SEQ LD NO 9615) '- GC CTG GAA AGC TGA G-3' (FRAG 237) (SEQ TD NO 9616) '- GC CTG GAA AGC TGA-3' (FRAG 238) (SEQ ID NO 9617) '- GC CTG GAA AGC TG-3' (FRAG 239) (SEQ ID NO 9618) '- GC CTG GAA AGC T-3' (FRAG 240) (SEQ ID NO 9619) '- GC CTG GAA AGC-3' (FRAG 2 1) (SEQ ID NO 9620) '- GC CTG GAA AG-3' (FRAG 242) (SEQ ID NO 9621) '- C CTG GAA AGC TGA GAT GG A GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 243) (SEQ ID NO 9622) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 244) (SEQ ID NO 9623) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 245) (SEQ ID NO 9624) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 246) (SEQ ID NO 9625) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 247) (SEQ TD NO 9626) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 248) (SEQ TD NO 9627) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 249) (SEQ ID NO 9628) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 250) (SEQ ID NO 9629) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 251) (SEQ ID NO 9630) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 252) (SEQ ID NO 9631) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 253) (SEQ TD NO 9632) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 254) (SEQ ID NO 9633) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 255) (SEQ ID NO 9634) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 256) (SEQ ID NO 9635) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 257) (SEQ ID NO 9636) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 258) (SEQ ID NO 9637) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT GG -3' (FRAG 259) (SEQ ID NO 9638) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT G -3' (FRAG 260) (SEQ ID NO 9639) '- C CTG GAA AGC TGA GAT GGA GGG CGG CAT -3' (FRAG 261) (SEQ ID NO 9640) '- C CTG GAA AGC TGA GAT GGA GGG CGG CA-3' (FRAG 262) (SEQ ID NO 9641) '- C CTG GAA AGC TGA GAT GGA GGG CGG C-3' (FRAG 263) (SEQ ID NO 9642) '- C CTG GAA AGC TGA GAT GGA GGG CGG -3' (FRAG 264) (SEQ ID NO 9643) '- C CTG GAA AGC TGA GAT GGA GGG CG -3' (FRAG 265) (SEQ TD NO 9644) '- C CTG GAA AGC TGA GAT GGA GGG C -3' (FRAG 266) (SEQ ID NO 9645) '- C CTG GAA AGC TGA GAT GGA GGG -3' (FRAG 267) (SEQ ID NO 9646) '- C CTG GAA AGC TGA GAT GGA GG -3' (FRAG 268) (SEQ ID NO 9647) '- C CTG GAA AGC TGA GAT GGA G -3' (FRAG 269) (SEQ ID NO 9648) '- C CTG GAA AGC TGA GAT GGA -3' (FRAG 270) (SEQ TD NO 9649) '- C CTG GAA AGC TGA GAT GG -3' (FRAG 271) (SEQ ID NO 9650) '- C CTG GAA AGC TGA GAT G -3' (FRAG 272) (SEQ ID NO 9651) '- C CTG GAA AGC TGA GAT -3' (FRAG 273) (SEQ ID NO 9652) '- C CTG GAA AGC TGA GA-3' (FRAG 274) (SEQ ID NO 9653) '- C CTG GAA AGC TGA G-3' (FRAG 275) (SEQ ID NO 9654) '- C CTG GAA AGC TGA-3' (FRAG 276) (SEQ ID NO 9655) '- C CTG GAA AGC TG-3' (FRAG 277) (SEQ ID NO 9656) '- C CTG GAA AGC T-3' (FRAG 278) (SEQ TD NO 9657) '- C CTG GAA AGC-3' (FRAG 279) (SEQ TD NO 9658) '- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 280) (SEQ ID NO 9659) '- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 281) (SEQ TD NO 9660) 5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 282) (SEQ TD NO 9661)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 283) (SEQ ID NO 9662)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 284) (SEQ ID NO 9663)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 285) (SEQ LD NO 9664) 5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 286) (SEQ TD NO 9665)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 287) (SEQ TD NO 9666)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 288) (SEQ TD NO 9667)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 289) (SEQ ID NO 9668)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 290) (SEQ ID NO 9669) 5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG291) (SEQ ID NO 9670)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 292) (SEQ TD NO 9671)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 293) (SEQ ID NO 9672)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 294) (SEQ ID NO 9673)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 295) (SEQ ID NO 9674) 5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT GG -3' (FRAG 296) (SEQ ID NO 9675)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT G -3' (FRAG 297) (SEQ TD NO 9676)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CAT -3' (FRAG 298) (SEQ ID NO 9677)

5'- CTG GAA AGC TGA GAT GGA GGG CGG CA-3' (FRAG 299) (SEQ ID NO 9678)

5'- CTG GAA AGC TGA GAT GGA GGG CGG C-3' (FRAG 300) (SEQ ID NO 9679) 5'- CTG GAA AGC TGA GAT GGA GGG CGG -3' (FRAG 301) (SEQ LD NO 9680)

5'- CTG GAA AGC TGA GAT GGA GGG CG -3' (FRAG 302) (SEQ ID NO 9681)

5'- CTG GAA AGC TGA GAT GGA GGG C -3' (FRAG 303) (SEQ ID NO 9682)

5'- CTG GAA AGC TGA GAT GGA GGG -3' (FRAG 304) (SEQ ID NO 9683)

5'- CTG GAA AGC TGA GAT GGA GG -3' (FRAG 305) (SEQ ID NO 9684) 5'- CTG GAA AGC TGA GAT GGA G -3' (FRAG 306) (SEQ ID NO 9685)

5'- CTG GAA AGC TGA GAT GGA -3' (FRAG 307) (SEQ ID NO 9686)

5'- CTG GAA AGC TGA GAT GG -3' (FRAG 308) (SEQ ID NO 9687)

5'- CTG GAA AGC TGA GAT G -3' (FRAG 309) (SEQ ID NO 9688)

5'- CTG GAA AGC TGA GAT -3' (FRAG310) (SEQ ID NO 9689) 5'- CTG GAA AGC TGA GA-3' (FRAG 311) (SEQ ID NO 9690)

5'- CTG GAA AGC TGA G-3' (FRAG 312) (SEQ ID NO 9691)

5'- CTG GAA AGC TGA-3' (FRAG 313) (SEQ ID NO 9692)

5'- CTG GAA AGC TG-3' (FRAG 314) (SEQ ID NO 9693)

5'- CTG GAA AGC T-3' (FRAG 315) (SEQ ID NO 9694) 5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 316) (SEQ ID NO 9695)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 317) (SEQ ID NO 9696)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 318) (SEQ ID NO 9697)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 319) (SEQ ID NO 9698)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 320) (SEQ ID NO 9699) 5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 321) (SEQ ID NO 9700)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 322) (SEQ ID NO 9701)

S- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 323) (SEQ ID NO 9702)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 324) (SEQ ID NO 9703)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 325) (SEQ TD NO 9704) S- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 326) (SEQ ID NO 9705)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 327) (SEQ ID NO 9706)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 328) (SEQ ID NO 9707)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 329) (SEQ ID NO 9708)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 330) (SEQ ID NO 9709) 5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 331) (SEQ ID NO 9710)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT GG -3' (FRAG 332) (SEQ ID NO 9711)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT G -3' (FRAG 333) (SEQ TD NO 9712)

5'- TG GAA AGC TGA GAT GGA GGG CGG CAT -3' (FRAG 334) (SEQ ID NO 9713)

5'- TG GAA AGC TGA GAT GGA GGG CGG CA-3' (FRAG335) (SEQ ID N0 9714) 5'- TG GAA AGC TGA GAT GGA GGG CGG C-3' (FRAG 336) (SEQ ID NO 9715)

5'- TG GAA AGC TGA GAT GGA GGG CGG -3' (FRAG 337) (SEQ ID NO 9716)

5'- TG GAA AGC TGA GAT GGA GGG CG -3' (FRAG 338) (SEQ ID NO 9717)

5'- TG GAA AGC TGA GAT GGA GGG C -3' (FRAG 339) (SEQ ID NO 9718)

5'- TG GAA AGC TGA GAT GGA GGG -3' (FRAG 340) (SEQ ID NO 9719) 5'- TG GAA AGC TGA GAT GGA GG -3' (FRAG 341) (SEQ ID NO 9720)

5'- TG GAA AGC TGA GAT GGA G -3' (FRAG 342) (SEQ ID NO 9721)

5'- TG GAA AGC TGA GAT GGA -3' (FRAG 343) (SEQ ID NO 9722)

5'- TG GAA AGC TGA GAT GG -3' (FRAG 344) (SEQ ID NO 9723)

5'- TG GAA AGC TGA GAT G -3' (FRAG 345) (SEQ TD NO 9724) 5'- TG GAA AGC TGA GAT -3' (FRAG 346) (SEQ ID NO 9725)

5'- TG GAA AGC TGA GA-3' (FRAG 347) (SEQ ID NO 9726)

5'- TG GAA AGC TGA G-3' (FRAG 348) (SEQ ID NO 9727)

5'- TG GAA AGC TGA-3' (FRAG 349) (SEQ ID NO 9728)

5'- TG GAA AGC TG-3' (FRAG 350) (SEQ ID NO 9729) 5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 351) (SEQ ID NO 9730)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 352) (SEQ ID NO 9731)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 353) (SEQ ID NO 9732)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 354) (SEQ ID NO 9733)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 355) (SEQ ID NO 9734) 5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 356) (SEQ ID NO 9735)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 357) (SEQ ID NO 9736)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 358) (SEQ ID NO 9737)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 359) (SEQ ID NO 9738)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 360) (SEQ ID NO 9739) 5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 361) (SEQ ID NO 9740)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 362) (SEQ TD NO 9741)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 363) (SEQ ID NO 9742)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 364) (SEQ TD NO 9743)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 365) (SEQ TD NO 9744) 5'- G GAA AGC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 366) (SEQ TD NO 9745)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT GG -3' (FRAG 367) (SEQ ID NO 9746)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT G -3' (FRAG 368) (SEQ ID NO 9747)

5'- G GAA AGC TGA GAT GGA GGG CGG CAT -3' (FRAG 369) (SEQ LD NO 9748)

5'- G GAA AGC TGA GAT GGA GGG CGG CA-3' (FRAG 370) (SEQ ID NO 9749) 5'- G GAA AGC TGA GAT GGA GGG CGG C-3' (FRAG 371) (SEQ ID NO 9750)

5'- G GAA AGC TGA GAT GGA GGG CGG -3' (FRAG 372) (SEQ ID NO 9751)

5'- G GAA AGC TGA GAT GGA GGG CG -3' (FRAG 373) (SEQ TD NO 9752)

5'- G GAA AGC TGA GAT GGA GGG C -3' (FRAG 374) (SEQ LD NO 9753)

5'- G GAA AGC TGA GAT GGA GGG -3' (FRAG 375) (SEQ ID NO 9754) 5'- G GAA AGC TGA GAT GGA GG -3' (FRAG 376) (SEQ ID NO 9755)

5'- G GAA AGC TGA GAT GGA G -3' (FRAG 377) (SEQ ID NO 9756)

5'- G GAA AGC TGA GAT GGA -3' (FRAG 378) (SEQ ID NO 9757)

5'- G GAA AGC TGA GAT GG -3' (FRAG 379) (SEQ LD NO 9758)

5'- G GAA AGC TGA GAT G -3' (FRAG 380) (SEQ TD NO 9759) '- G GAA AGC TGA GAT -3' (FRAG 381) (SEQ ID NO 9760) '- G GAA AGC TGA GA-3' (FRAG 382) (SEQ TD NO 9761) '- G GAA AGC TGA G-3' (FRAG 383) (SEQ ID NO 9762) '- G GAA AGC TGA-3' (FRAG 384) (SEQ ID NO 9763) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 385) (SEQ ID NO 9764) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 386) (SEQ LD NO 9765) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 387) (SEQ TD NO 9766) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 388) (SEQ DO NO 9767) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 389) (SEQ TD NO 9768) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 390) (SEQ TD NO 9769) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 391) (SEQ ID NO 9770) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 392) (SEQ TD NO 9771) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 393) (SEQ ID NO 9772) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 394) (SEQ ID NO 9773) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 395) (SEQ TD NO 9774) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 396) (SEQ ID NO 9775) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 397) (SEQ TD NO 9776) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 398) (SEQ ID NO 9777) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 399) (SEQ ID NO 9778) '- GAA AGC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 400) (SEQ TD NO 9779) '- GAA AGC TGA GAT GGA GGG CGG CAT GG -3' (FRAG 401) (SEQ TD NO 9780) '- GAA AGC TGA GAT GGA GGG CGG CAT G -3' (FRAG 402) (SEQ ID NO 9781) '- GAA AGC TGA GAT GGA GGG CGG CAT -3' (FRAG 403) (SEQ ID NO 9782) '- GAA AGC TGA GAT GGA GGG CGG CA-3' (FRAG 404) (SEQ TD NO 9783) '- GAA AGC TGA GAT GGA GGG CGG C-3' (FRAG 405) (SEQ TD NO 9784) '- GAA AGC TGA GAT GGA GGG CGG -3' (FRAG 406) (SEQ ID NO 9785) '- GAA AGC TGA GAT GGA GGG CG -3' (FRAG 407) (SEQ TD NO 9786) '- GAA AGC TGA GAT GGA GGG C -3' (FRAG 408) (SEQ ID NO 9787) '- GAA AGC TGA GAT GGA GGG -3' (FRAG 409) (SEQ TD NO 9788) '- GAA AGC TGA GAT GGA GG -3' (FRAG 410) (SEQ ID NO 9789) '- GAA AGC TGA GAT GGA G -3' (FRAG 411) (SEQ ID NO 9790) '- GAA AGC TGA GAT GGA -3' (FRAG 412) (SEQ ID NO 9791) '- GAA AGC TGA GAT GG -3' (FRAG 413) (SEQ ID NO 9792) '- GAA AGC TGA GAT G -3' (FRAG 414) (SEQ ID NO 9793) '- GAA AGC TGA GAT -3' (FRAG 415) (SEQ TD NO 9794) '- GAA AGC TGA GA-3' (FRAG 16) (SEQ ID NO 9795) '- GAA AGC TGA G-3' (FRAG 417) (SEQ ID NO 9796) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 418) (SEQ ID NO 9797) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 419) (SEQ TD NO 9798) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 420) (SEQ TD NO 9799) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 421) (SEQ ID NO 9800) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 422) (SEQ ID NO 9801) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 423) (SEQ ID NO 9802) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3'(FRAG 424) (SEQ ID NO 9803) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 425) (SEQ TD NO 9804) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 426) (SEQ TD NO 9805) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 427) (SEQ ID NO 9806) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 428) (SEQ ID NO 9807) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 429) (SEQ ID NO 9808) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 430) (SEQ TD NO 9809) '- AA AGC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 431) (SEQ ID NO 9810) '- AA AGC TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 432) (SEQ ID NO 9811) '- AA AGC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 433) (SEQ ID NO 9812) '- AAAGC TGA GAT GGA GGG CGG CAT GG -3' (FRAG434) (SEQ ID N0 9813) '- AA AGC TGA GAT GGA GGG CGG CAT G -3' (FRAG 435) (SEQ ID NO 9814) '- AA AGC TGA GAT GGA GGG CGG CAT -3' (FRAG 436) (SEQ TD NO 9815) '- AA AGC TGA GAT GGA GGG CGG CA-3' (FRAG 437) (SEQ ID HO 9816) '- AA AGC TGA GAT GGA GGG CGG C-3' (FRAG 438) (SEQ ID NO 9817) '- AA AGC TGA GAT GGA GGG CGG -3' (FRAG 439) (SEQ ID NO 9818) '- AA AGC TGA GAT GGA GGG CG -3' (FRAG 440) (SEQ ID NO 9819) '- AA AGC TGA GAT GGA GGG C -3' (FRAG 441) (SEQ ID NO 9820) '- AA AGC TGA GAT GGA GGG -3' (FRAG 442) (SEQ ID NO 9821) '- AA AGC TGA GAT GGA GG -3' (FRAG 443) (SEQ TD NO 9822) '- AA AGC TGA GAT GGA G -3' (FRAG 444) (SEQ TD NO 9823) '- AA AGC TGA GAT GGA -3' (FRAG 445) (SEQ TD NO 9824) '- AA AGC TGA GAT GG -3' (FRAG 446) (SEQ ID NO 9825) '- AA AGC TGA GAT G -3' (FRAG 447) (SEQ ID NO 9826) '- AA AGC TGA GAT -3' (FRAG 448) (SEQ ID NO 9827) '- AA AGC TGA GA-3' (FRAG 449) (SEQ TD NO 9828) '- A AGC TGA GAT GGA GGG CG G CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 450) (SEQ DO NO 9829) '- A AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 451) (SEQ ID NO 9830) '- A AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 452) (SEQ ID NO 9831) '- A AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 453) (SEQ TD NO 9832) '- A AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 454) (SEQ TD NO 9833) '- A AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 455) (SEQ TD NO 9834) '- A AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 456) (SEQ ID NO 9835) '- A AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 457) (SEQ DO NO 9836) '- A AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 458) (SEQ ID NO 9837) '- A AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 459) (SEQ ID NO 9838) '- A AGC TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 460) (SEQ TD NO 9839) '- A AGC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 461) (SEQ ID NO 9840) '- A AGC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 462) (SEQ TD NO 9841) '- A AGC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 463) (SEQ DD NO 9842) '- A AGC TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 464) (SEQ TD NO 9843) '- A AGC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 465) (SEQ ID NO 9844) '- A AGC TGA GAT GGA GGG CGG CAT GG -3' (FRAG 466) (SEQ ID NO 9845) '- A AGC TGA GAT GGA GGG CGG CAT G -3' (FRAG 467) (SEQ ID NO 9846) '- A AGC TGA GAT GGA GGG CGG CAT -3' (FRAG 468) (SEQ ID NO 9847) '- A AGC TGA GAT GGA GGG CGG CA-3' (FRAG 469) (SEQ ID NO 9848) '- A AGC TGA GAT GGA GGG CGG C-3' (FRAG 470) (SEQ ID NO 9849) '- A AGC TGA GAT GGA GGG CGG -3' (FRAG 471) (SEQ DO NO 9850) '- A AGC TGA GAT GGA GGG CG -3' (FRAG 472) (SEQ TD NO 9851) '- A AGC TGA GAT GGA GGG C -3' (FRAG 473) (SEQ DO NO 9852) '- A AGC TGA GAT GGA GGG -3' (FRAG 474) (SEQ TD NO 9853) '- A AGC TGA GAT GGA GG -3' (FRAG 475) (SEQ DO NO 9854) '- A AGC TGA GAT GGA G -3' (FRAG 476) (SEQ BO NO 9855) '- A AGC TGA GAT GGA -3' (FRAG 477) (SEQ TD NO 9856) '- A AGC TGA GAT GG -3' (FRAG 478) (SEQ ID NO 9857) '- A AGC TGA GAT G -3' (FRAG 479) (SEQ D3 NO 9858) '- A AGC TGA GAT -3' (FRAG 480) (SEQ ID NO 9859) '- AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 481) (SEQ ID NO 9860 '- AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 482) (SEQ ID NO 9861) '- AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 483) (SEQ TD NO 9862) '- AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 484) (SEQ DO NO 9863) '- AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 485) (SEQ TD NO 9864) '- AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 486) (SEQ TD NO 9865) '- AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 487) (SEQ DO NO 9866) '- AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 488) (SEQ DO NO 9867) '- AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 489) (SEQ DO NO 9868) '- AGC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 490) (SEQ ED NO 9869) '- AGC TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 491) (SEQ DO NO 9870) '- AGC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 492) (SEQ ID NO 9871) '- AGC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 493) (SEQ TD NO 9872) '- AGC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 494) (SEQ ID NO 9873) '- AGC TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 495) (SEQ TD NO 9874) '- AGC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 496) (SEQ ID NO 9875) '- AGC TGA GAT GGA GGG CGG CAT GG -3' (FRAG 497) (SEQ TD NO 9876) '- AGC TGA GAT GGA GGG CGG CAT G-3' (FRAG 498) (SEQ DO NO 9877) '- AGC TGA GAT GGA GGG CGG CAT -3' (FRAG 499) (SEQ TD NO 9878) '- AGC TGA GAT GGA GGG CGG CA-3' (FRAG 500) (SEQ DO NO 9879) '- AGC TGA GAT GGA GGG CGG C-3' (FRAG 501) (SEQ DD NO 98S0) '- AGC TGA GAT GGA GGG CGG -3' (FRAG 502) (SEQ DO NO 9881) '- AGC TGA GAT GGA GGG CG -3' (FRAG 503) (SEQ TD NO 9882) '- AGC TGA GAT GGA GGG C -3' (FRAG 504) (SEQ DD NO 9883) '- AGC TGA GAT GGA GGG -3' (FRAG 505) (SEQ DD NO 9884) '- AGC TGA GAT GGA GG -3' (FRAG 506) (SEQ ID NO 9885) '- AGC TGA GAT GGA G -3' (FRAG 507) (SEQ DD NO 9886) '- AGC TGA GAT GGA -3' (FRAG 508) (SEQ ID NO 9887) '- AGC TGA GAT GG-3' (FRAG 509) (SEQ DD NO 9888) '- AGC TGA GAT G -3' (FRAG 510) (SEQ ID NO 9889) '- GC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 511) (SEQ DD NO 9890) '- GC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 512) (SEQ DD NO 9891) '- GC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 513) (SEQ DD NO 9892) '- GC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 514) (SEQ ID NO 9893) '- GC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 515) (SEQ DD NO 9894) '- GC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 516) (SEQ DD NO 9895) '- GC TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 517) (SEQ DD NO 9896) '- GC TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 518) (SEQ DD NO 9897) '- GC TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 519) (SEQ DD NO 9898) '- GC TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 520) (SEQ D NO 9899) '- GC TGA GAT GGA GGG CGG CAT GGC GGG CA 3' (FRAG 521) (SEQ DD NO 9900) '- GC TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 522) (SEQ DD NO 9901) '- GC TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 523) (SEQ DD NO 9902) '- GC TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 524) (SEQ DD NO 9903) '- GC TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 525) (SEQ DD NO 9904) '- GC TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 526) (SEQ DD NO 9905) '- GC TGA GAT GGA GGG CGG CAT GG -3' (FRAG 527) (SEQ DD NO 9906) '- GC TGA GAT GGA GGG CGG CAT G -3' (FRAG 528) (SEQ ID NO 9907) '- GC TGA GAT GGA GGG CGG CAT -3' (FRAG 529) (SEQ ID NO 9908) '- GC TGA GAT GGA GGG CGG CA-3' (FRAG 530) (SEQ ID NO 9909) '- GC TGA GAT GGA GGG CGG C-3' (FRAG 531) (SEQ ID NO 9910) '- GC TGA GAT GGA GGG CGG -3' (FRAG 532) (SEQ DD NO 9911) '- GC TGA GAT GGA GGG CG -3' (FRAG 533) (SEQ DD NO 9912) '- GC TGA GAT GGA GGG C -3' (FRAG 534) (SEQ DD NO 9913) '- GC TGA GAT GGA GGG -3' (FRAG 535) (SEQ ID NO 9914) '- GC TGA GAT GGA GG -3' (FRAG 536) (SEQ DD NO 9915) '- GC TGA GAT GGA G -3' (FRAG 537) (SEQ DD NO 9916) '- GC TGA GAT GGA -3' (FRAG 538) (SEQ ID NO 9917) '- GC TGA GAT GG -3' (FRAG 539) (SEQ DD NO 9918) '- C TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 540) (SEQ ID NO 9919) '- C TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 541) (SEQ DD NO 9920) '- C TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 542) (SEQ ID NO 9921) '- C TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 543) (SEQ DD NO 9922) '- C TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 544) (SEQ DD NO 9923) '- C TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 545) (SEQ DD NO 9924) '- C TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 546) (SEQ DD NO 9925) '- C TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 547) (SEQ DD NO 9926) '- C TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 548) (SEQ DD NO 9927) '- C TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 549) (SEQ DD NO 9928) '- C TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 550) (SEQ DD NO 9929) '- C TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 551) (SEQ DD NO 9930) '- C TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 552) (SEQ DD NO 9931) '- C TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 553) (SEQ DD NO 9932) '- C TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 554) (SEQ DD NO 9933) '- C TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 555) (SEQ DD NO 9934) *- C TGA GAT GGA GGG CGG CAT GG -3' (FRAG 556) (SEQ DD NO 9935) '- C TGA GAT GGA GGG CGG CAT G -3' (FRAG 557) (SEQ DD NO 9936) '- C TGA GAT GGA GGG CGG CAT -3' (FRAG 558) (SEQ ID NO 9937) '- C TGA GAT GGA GGG CGG CA-3' (FRAG 559) (SEQ ID NO 9938) '- C TGA GAT GGA GGG CGG C-3' (FRAG 560) (SEQ DD NO 9939) '- C TGA GAT GGA GGG CGG -3' (FRAG 561) (SEQ DD NO 9940) '- C TGA GAT GGA GGG CG -3' (FRAG 562) (SEQ DD NO 9941) '- C TGA GAT GGA GGG C -3' (FRAG 563) (SEQ LD NO 9942) '- C TGA GAT GGA GGG -3' (FRAG 564) (SEQ ID NO 9943) '- C TGA GAT GGA GG -3' (FRAG 565) (SEQ DD NO 9944) '- C TGA GAT GGA G -3' (FRAG 566) (SEQ NO 9945) '- C TGA GAT GGA -3' (FRAG 567) (SEQ ID NO 9946) '- TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 568) (SEQ DD NO 9947) '- TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 569) (SEQ ID NO 9948) '- TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 570) (SEQ DD NO 9949) '- TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 571) (SEQ DD NO 9950) '- TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 572) (SEQ DD NO 9951) '- TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 573) (SEQ DD NO 9952) '- TGA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 574) (SEQ DD NO 9953) '- TGA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 575) (SEQ DD NO 9954) '- TGA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 576) (SEQ DD NO 9955) '- TGA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 577) (SEQ DD NO 9956) '- TGA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 578) (SEQ DD NO 9957) 5'- TGA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 579) (SEQ DD NO 9958)

5'- TGA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 580) (SEQ DD NO 9959)

5'- TGA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 581) (SEQ D O 9960)

5'- TGA GAT GGA GGG CGG CAT GGC G-3' (FRAG 582) (SEQ DO NO 9961) 5'- TGA GAT GGA GGG CGG CAT GGC -3' (FRAG 583) (SEQ DD NO 9962)

5'- TGA GAT GGA GGG CGG CAT GG -3' (FRAG 584) (SEQ DD NO 9963)

5'- TGA GAT GGA GGG CGG CAT G -3' (FRAG 585) (SEQ DD NO 9964)

5'- TGA GAT GGA GGG CGG CAT -3' (FRAG 586) (SEQ DD NO 9965)

5'- TGA GAT GGA GGG CGG CA-3' (FRAG 587) (SEQ ID NO 9966) 5'- TGA GAT GGA GGG CGG C-3' (FRAG 5S8) (SEQ DD NO 9967)

5'- TGA GAT GGA GGG CGG -3' (FRAG 589) (SEQ DD NO 9968)

5'- TGA GAT GGA GGG CG -3' (FRAG 590) (SEQ DD NO 9969)

5'- TGA GAT GGA GGG C -3' (FRAG 591) (SEQ DD NO 9970)

5'- TGA GAT GGA GGG -3' (FRAG 592) (SEQ ID NO 9971) 5'- TGA GAT GGA GG -3' (FRAG 593) (SEQ DD NO 9972)

5'- TGA GAT GGA G -3' (FRAG 594) (SEQ DD NO 9973)

5'- GA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 595) (SEQ DD NO 9974)

5'- GA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 596) (SEQ DD NO 9975)

5'- GA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 597) (SEQ DD NO 9976) 5'- GA GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 598) (SEQ DD NO 9977)

5'- GA GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 599) (SEQ ID NO 9978)

5'- GA GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 600) (SEQ DD NO 9979)

5'- GA GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 601) (SEQ DD NO 9980)

5'- GA GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 602) (SEQ DD NO 9981) 5'- GA GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 603) (SEQ DD NO 9982)

5'- GA GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 604) (SEQ DD NO 9983)

5'- GA GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 605) (SEQ DD NO 9984)

5'- GA GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 606) (SEQ DD NO 9985)

5'- GA GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 607) (SEQ DD NO 9986) 5'- GA GAT GGA GGG CGG CAT GGC GG-3' (FRAG 608) (SEQ DD NO 9987)

5'- GA GAT GGA GGG CGG CAT GGC G-3' (FRAG 609) (SEQ ID NO 9988)

5'- GA GAT GGA GGG CGG CAT GGC -3' (FRAG 610) (SEQ DD NO 9989)

5'- GA GAT GGA GGG CGG CAT GG -3' (FRAG 611) (SEQ DD NO 9990)

5'- GA GAT GGA GGG CGG CAT G -3' (FRAG 612) (SEQ ID NO 9991) 5'- GA GAT GGA GGG CGG CAT -3' (FRAG 613) (SEQ ID NO 9992)

5'- GA GAT GGA GGG CGG CA-3' (FRAG 614) (SEQ ID NO 9993)

S- GA GAT GGA GGG CGG C-3' (FRAG 615) (SEQ DD NO 9994)

5'- GA GAT GGA GGG CGG -3' (FRAG 616) (SEQ ID NO 9995)

5'- GA GAT GGA GGG CG -3' (FRAG 617) (SEQ DDNO 9996) 5'- GA GAT GGA GGG C -3' (FRAG 618) (SEQ DD NO 9997)

5'- GA GAT GGA GGG -3' (FRAG 619) (SEQ DD NO 9998)

5'- GA GAT GGA GG -3' (FRAG 620) (SEQ DD NO 9999)

5'- A GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 621) (SEQ DD NO 10000)

S- A GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 622) (SEQ DD NO 10001) 5'- A GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 623) (SEQ DD NO 10002)

5'- A GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 624) (SEQ DD NO 10003)

5'- A GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 625) (SEQ DD NO 10004)

5'- A GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 626) (SEQ DD NO 10005)

5'- A GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 627) (SEQ ID NO 10006) 5'- A GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 628) (SEQ DD NO 10007)

5'- A GAT GGA GGG CGG CAT GGC GGG CAC A 3' (FRAG 629) (SEQ ID NO 10008)

5'- A GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 630) (SEQ DD NO 10009)

5'- A GAT GGA GGG CGG CAT GGC GGG CA-3* (FRAG 631) (SEQ DD NO 10010)

5'- A GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 632) (SEQ DD NO 10011) 5'- A GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 633) (SEQ DD O 10012)

5'- A GAT GGA GGG CGG CAT GGC GG-3' (FRAG 634) (SEQ DDNO 10013)

5'- A GAT GGA GGG CGG CAT GGC G-3' (FRAG 635) (SEQ DD NO 10014)

5'- A GAT GGA GGG CGG CAT GGC -3' (FRAG 636) (SEQ ID NO 10015)

5'- A GAT GGA GGG CGG CAT GG -3' (FRAG 637) (SEQ DD NO 10016) 5'- A GAT GGA GGG CGG CAT G -3' (FRAG 638) (SEQ ID NO 10017)

5'- A GAT GGA GGG CGG CAT -3' (FRAG 639) (SEQ DD NO 10018)

5'- A GAT GGA GGG CGG CA-3' (FRAG 640) (SEQ DD NO 10019)

5'- A GAT GGA GGG CGG C-3' (FRAG 641) (SEQ DD NO 10020)

5'- A GAT GGA GGG CGG -3' (FRAG 642) (SEQ LD NO 10021) 5'- A GAT GGA GGG CG -3' (FRAG 643) (SEQ ID NO 10022)

5'- A GAT GGA GGG C -3' (FRAG 644) (SEQ ID NO 10023)

5'- A GAT GGA GGG -V (FRAG 645) (SEQ ID NO 10024)

5'- GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 646) (SEQ ID NO 10025)

5'- GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 647) (SEQ D O 10026) 5'- GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 648) (SEQ DD NO 10027)

5'- GAT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 6) (SEQ DD NO 10028)

5'- GAT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 650) (SEQ TD NO 10029)

5'- GAT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 651) (SEQ DD NO 10030)

5'- GAT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 652) (SEQ DDNO 10031) 5'- GAT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 653) (SEQ DD NO 10032)

5'- GAT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 654) (SEQ DD NO 10033)

5'- GAT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 655) (SEQ DD NO 10034)

5'- GAT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 656) (SEQ DD NO 10035)

5'- GAT GGA GGG CGG CAT GGC GGG C-3' (FRAG 657) (SEQ DD NO 10036) 5'- GAT GGA GGG CGG CAT GGC GGG -3' (FRAG 658) (SEQ DD NO 10037)

5'- GAT GGA GGG CGG CAT GGC GG-3' (FRAG 659) (SEQ DD NO 10038)

5'- GAT GGA GGG CGG CAT GGC G-3' (FRAG 660) (SEQ DD NO 10039)

5'- GAT GGA GGG CGG CAT GGC -3' (FRAG 661) (SEQ ID NO 10040)

5'- GAT GGA GGG CGG CAT GG -3' (FRAG 662) (SEQ DD NO 10041) 5'- GAT GGA GGG CGG CAT G -3' (FRAG 663) (SEQ ID NO 10042)

5'- GAT GGA GGG CGG CAT -3' (FRAG 664) (SEQ DD NO 10043)

5'- GAT GGA GGG CGG CA-3' (FRAG 665) (SEQ DD NO 10044)

5'- GAT GGA GGG CGG C-3' (FRAG 666) (SEQ DD NO 10045)

5'- GAT GGA GGG CGG -3' (FRAG 667) (SEQ DD NO 10046) 5'- GAT GGA GGG CG -3' (FRAG 668) (SEQ DD NO 10047)

5'- GAT GGA GGG C -3' (FRAG 669) (SEQ DD NO 10048)

5'- AT GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 670) (SEQ DD NO 10049)

5'- AT GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 671) (SEQ DD NO 10050)

5'- AT GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 672) (SEQ DD NO 10051) 5'- AT GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 673) (SEQ DD NO 10052)

5'- AT GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 674) (SEQ DD NO 10053)

5'- AT GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 675) (SEQ DD NO 10054)

5'- AT GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 676) (SEQ DD NO 10055)

5V AT GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 677) (SEQ DD NO 10056) '- AT GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 678) (SEQ DD NO 10057) '- AT GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 679) (SEQ DD NO 10058) '- AT GGA GGG CGG CAT GGC GGG CA-3' (FRAG 680) (SEQ ID NO 10059) '- AT GGA GGG CGG CAT GGC GGG C-3' (FRAG 681) (SEQ DD NO 10060) '- AT GGA GGG CGG CAT GGC GGG -3' (FRAG 682) (SEQ D O 10061) '- AT GGA GGG CGG CAT GGC GG-3' (FRAG 683) (SEQ DD NO 10062) '- AT GGA GGG CGG CAT GGC G-3' (FRAG 684) (SEQ DD NO 10063) '- AT GGA GGG CGG CAT GGC -3' (FRAG 685) (SEQ DD NO 10064) '- AT GGA GGG CGG CAT GG -3' (FRAG 686) (SEQ DD NO 10065) '- AT GGA GGG CGG CAT G -3' (FRAG 687) (SEQ DD NO 10066) '- AT GGA GGG CGG CAT -3' (FRAG 688) (SEQ DD NO 10067) '- AT GGA GGG CGG CA-3' (FRAG 689) (SEQ TD NO 10068) '- AT GGA GGG CGG C-3' (FRAG 690) (SEQ DD NO 10069) '- AT GGA GGG CGG -3' (FRAG 691) (SEQ DD NO 10070) '- AT GGA GGG CG -3' (FRAG 692) (SEQ DD NO 10071) '- T GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 693) (SEQ TD NO 10072) '- T GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 694) (SEQ DD NO 10073) '- T GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 695) (SEQ ID NO 10074) '- T GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 696) (SEQ DD NO 10075) '- T GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 697) (SEQ DD NO 10076) '- T GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 698) (SEQ DD NO 10077) '- T GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 699) (SEQ DD NO 10078) '- T GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 700) (SEQ DD NO 10079) '- T GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 701) (SEQ DD NO 10080) '- T GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 702) (SEQ DD NO 10081) '- T GGA GGG CGG CAT GGC GGG CA-3' (FRAG 703) (SEQ D O 10082) '- T GGA GGG CGG CAT GGC GGG C-3' (FRAG 704) (SEQ ID NO 10083) '- T GGA GGG CGG CAT GGC GGG -3' (FRAG 705) (SEQ DD NO 10084) '- T GGA GGG CGG CAT GGC GG-3' (FRAG 706) (SEQ DD NO 10085) '- T GGA GGG CGG CAT GGC G-3' (FRAG 707) (SEQ DD NO 10086) '- T GGA GGG CGG CAT GGC -3' (FRAG 708) (SEQ DD NO 10087) '- T GGA GGG CGG CAT GG -3' (FRAG 709) (SEQ DD NO 10088) '- T GGA GGG CGG CAT G-3' (FRAG 710) (SEQ DD NO 10089) '- T GGA GGG CGG CAT -3' (FRAG 711) (SEQ DD NO 10090) '- T GGA GGG CGG CA-3' (FRAG 712) (SEQ DD NO 10091) '- T GGA GGG CGG C-3' (FRAG 713) (SEQ ID NO 10092) '- T GGA GGG CGG-3' (FRAG 714) (SEQ ID NO 10093) '- GGA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 715) (SEQ DD NO 10094) '- GGA GGG CGG CAT GGC GGG CAC AGG CTG GG-3" (FRAG 716) (SEQ DD NO 10095) '- GGA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 717) (SEQ DDNO 10096) '- GGA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 718) (SEQ DD NO 10097) '- GGA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 719) (SEQ ID NO 10098) '- GGA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 720) (SEQ DD NO 10099) '- GGA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 721) (SEQ ID NO 10100) '- GGA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 722) (SEQ DD NO 10101) '- GGA GGG CGG CAT GGC GGG CAC A-3' (FRAG 723) (SEQ DD NO 10102) '- GGA GGG CGG CAT GGC GGG CAC-3' (FRAG 724) (SEQ ID NO 10103) '- GGA GGG CGG CAT GGC GGG CA-3' (FRAG 725) (SEQ DD NO 10104) '- GGA GGG CGG CAT GGC GGG C-3' (FRAG 726) (SEQ DD NO 10105) '- GGA GGG CGG CAT GGC GGG -3' (FRAG 727) (SEQ ID NO 10106) '- GGA GGG CGG CAT GGC GG-3' (FRAG 728) (SEQ DD NO 10107) '- GGA GGG CGG CAT GGC G-3' (FRAG 729) (SEQ ID NO 10108) '- GGA GGG CGG CAT GGC -3' (FRAG 730) (SEQ DD NO 10109) '- GGA GGG CGG CAT GG -3' (FRAG 731) (SEQ DDNO 10110) '- GGA GGG CGG CAT G -3' (FRAG 732) (SEQ ID NO 10111) '- GGA GGG CGG CAT -3' (FRAG 733) (SEQ DD NO 10112) '- GGA GGG CGG CA-3' (FRAG 734) (SEQ ID NO 10113) '- GGA GGG CGG C-3' (FRAG 735) (SEQ DD NO 10114) '- GA GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 736) (SEQ DD NO 10115) '- GA GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 737) (SEQ DD NO 10116) '- GA GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 738) (SEQ DD NO 10117) '- GA GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 739) (SEQ DD NO 10118) '- GA GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 740) (SEQ DD NO 10119) '- GA GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 741) (SEQ DD NO 10120) '- GA GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 742) (SEQ ID NO 10121) '- GA GGG CGG CAT GGC GGG CAC AG-3' (FRAG 743) (SEQ DD NO 10122) '- GA GGG CGG CAT GGC GGG CAC A-3' (FRAG 744) (SEQ ID NO 10123) '- GA GGG CGG CAT GGC GGG CAC-3' (FRAG 745) (SEQ D NO 10124) '- GA GGG CGG CAT GGC GGG CA-3' (FRAG 746) (SEQ DD NO 10125) '- GA GGG CGG CAT GGC GGG C-3' (FRAG 747) (SEQ ID NO 10126) '- GA GGG CGG CAT GGC GGG -3' (FRAG 748) (SEQ DD NO 10127) '- GA GGG CGG CAT GGC GG-3' (FRAG 749) (SEQ DD NO 10128) '- GA GGG CGG CAT GGC G-3' (FRAG 750) (SEQ DD NO 10129) '- GA GGG CGG CAT GGC -3' (FRAG 751) (SEQ DD NO 10130) '- GA GGG CGG CAT GG -3' (FRAG 752) (SEQ DD NO 10131) '- GA GGG CGG CAT G -3' (FRAG 753) (SEQ ID NO 10132) '- GA GGG CGG CAT -3' (FRAG 754) (SEQ DD NO 10133) '- GA GGG CGG CA-3' (FRAG 755) (SEQ ID NO 10134) '- A GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 756) (SEQ DD NO 10135) '- A GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 757) (SEQ ID NO 10136) '- A GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 758) (SEQ ID NO 10137) '- A GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 759) (SEQ DD NO 10138) '- A GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 760) (SEQ DD NO 10139) '- A GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 761) (SEQ DD NO 10140) '- A GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 762) (SEQ DD NO 10141) '- A GGG CGG CAT GGC GGG CAC AG-3' (FRAG 763) (SEQ ID NO 10142) '- A GGG CGG CAT GGC GGG CAC A-3' (FRAG 764) (SEQ DD NO 10143) '- A GGG CGG CAT GGC GGG CAC-3' (FRAG 765) (SEQ DD NO 10144) '- A GGG CGG CAT GGC GGG CA-3' (FRAG 766) (SEQ DD NO 10145) '- A GGG CGG CAT GGC GGG C-3' (FRAG 767) (SEQ DD NO 10146) '- A GGG CGG CAT GGC GGG -3' (FRAG 768) (SEQ DD NO 10147) '- A GGG CGG CAT GGC GG-3' (FRAG 769) (SEQ DD NO 10148) '- A GGG CGG CAT GGC G-3' (FRAG 770) (SEQ DD NO 10149) '- A GGG CGG CAT GGC -3' (FRAG 771) (SEQ ID NO 10150) '- A GGG CGG CAT GG-3' (FRAG 772) (SEQ DD NO 10151) '- A GGG CGG CAT G-3" (FRAG 773) (SEQ DD NO 10152) '- A GGG CGG CAT -3' (FRAG 774) (SEQ DD NO 10153) '- GGG CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 775) (SEQ DD O 10154) '- GGG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 776) (SEQ DD NO 10155) '- GGG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 777) (SEQ DD KO 10156) '- GGG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 778) (SEQ TD NO 10157) '- GGG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 779) (SEQ DD O 10158) '- GGG CGG CAT GGC GGG CAC AGG C-3' (FRAG 780) (SEQ DD NO 10159) '- GGG CGG CAT GGC GGG CAC AGG -3' (FRAG 781) (SEQ DD NO 10160) '- GGG CGG CAT GGC GGG CAC AG-3' (FRAG 782) (SEQ DD NO 10161) '- GGG CGG CAT GGC GGG CAC A-3' (FRAG 783) (SEQ DD NO 10162) '- GGG CGG CAT GGC GGG CAC-3' (FRAG 784) (SEQ DD NO 10163) '- GGG CGG CAT GGC GGG CA-3' (FRAG 785) (SEQ DD NO 10164) '- GGG CGG CAT GGC GGG C-3' (FRAG 786) (SEQ DD NO 10165) '- GGG CGG CAT GGC GGG -3' (FRAG 787) (SEQ DD NO 10166) '- GGG CGG CAT GGC GG-3' (FRAG 788) (SEQ DD NO 10167) '- GGG CGG CAT GGC G-3' (FRAG 789) (SEQ DD NO 10168) '- GGG CGG CAT GGC -3' (FRAG 790) (SEQ DD NO 10169) '- GGG CGG CAT GG -3' (FRAG 791) (SEQ DD NO 10170) '- GGG CGG CAT G-3¹ (FRAG 792) (SEQ DDNO 10171) '- GG CGG CAT GGC GGG CAC AG G CTG GGC-3' (FRAG 793) (SEQ DD NO 10172) '- GG CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 794) (SEQ DD NO 10173) '- GG CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 795) (SEQ DD NO 10174) '- GG CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 796) (SEQ DD NO 10175) '- GG CGG CAT GGC GGG CAC AGG CT-3' (FRAG 797) (SEQ DD NO 10176) '- GG CGG CAT GGC GGG CAC AGG C-3' (FRAG 798) (SEQ DD NO 10177) '- GG CGG CAT GGC GGG CAC AGG -3' (FRAG 799) (SEQ DD NO 10178) '- GG CGG CAT GGC GGG CAC AG-3' (FRAG 800) (SEQ ID NO 10179) '- GG CGG CAT GGC GGG CAC A-3' (FRAG 801) (SEQ DD NO 10180) '- GG CGG CAT GGC GGG CAC-3' (FRAG 802) (SEQ DD NO 10181) '- GG CGG CAT GGC GGG CA-3' (FRAG 803) (SEQ DD NO 10182) '- GG CGG CAT GGC GGG C-3' (FRAG 804) (SEQ ID NO 10183) '- GG CGG CAT GGC GGG -3' (FRAG 805) (SEQ ID NO 10184) '- GG CGG CAT GGC GG-3' (FRAG 806) (SEQ TD NO 10185) '- GG CGG CAT GGC G-3' (FRAG 807) (SEQ ID NO 10186) '- GG CGG CAT GGC -3' (FRAG 808) (SEQ ID NO 10187) '- GG CGG CAT GG -3' (FRAG 809) (SEQ DD NO 10188) '- G CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 810) (SEQ DDNO 10189) '- G CGG CAT GGC GGG CAC AGG CTG GG 3' (FRAG 811) (SEQ DDNO 10190) '- G CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 812) (SEQ DD NO 10191) '- G CGG CAT GGC GGG CAC AGG CTG-3' (FRAG 813) (SEQ DD NO 10192) '- G CGG CAT GGC GGG CAC AGG CT-3' (FRAG 814) (SEQ ED NO 10193) '- G CGG CAT GGC GGG CAC AGG C-3' (FRAG 815) (SEQ ID NO 10194) '- G CGG CAT GGC GGG CAC AGG -3' (FRAG 816) (SEQ DD O 10195) '- G CGG CAT GGC GGG CAC AG-3' (FRAG 817) (SEQ DD NO 10196) '- G CGG CAT GGC GGG CAC A-3' (FRAG 818) (SEQ ID NO 10197) '- G CGG CAT GGC GGG CAC 3' (FRAG 819) (SEQ DD NO 10198) '- G CGG CAT GGC GGG CA-3' (FRAG 820) (SEQ DD NO 10199) '- G CGG CAT GGC GGG C-3' (FRAG 821) (SEQ ID NO 10200) '- G CGG CAT GGC GGG -3' (FRAG 822) (SEQ ID NO 10201) '- G CGG CAT GGC GG-3' (FRAG 823) (SEQ DD NO 10202) '- G CGG CAT GGC G-3' (FRAG 824) (SEQ DD NO 10203) '- G CGG CAT GGC -3' (FRAG 825) (SEQ DD O 10204) '- CGG CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 826) (SEQ ID NO 10205) '- CGG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 827) (SEQ ID NO 10206) '- CGG CAT GGC GGG CAC AGG CTG G-3' (FRAG 828) (SEQ ID NO 10207) '- CGG CAT GGC GGG CAC AGG CTG -3' (FRAG 829) (SEQ DD NO 10208) '- CGG CAT GGC GGG CAC AGG CT-3' (FRAG 830) (SEQ ID NO 10209) '- CGG CAT GGC GGG CAC AGG C-3' (FRAG 831) (SEQ DD NO 10210) '- CGG CAT GGC GGG CAC AGG -3' (FRAG 832) (SEQ DD NO 10211) '- CGG CAT GGC GGG CAC AG-3' (FRAG 833) (SEQ DD NO 10212) '- CGG CAT GGC GGG CAC A-3' (FRAG 834) (SEQ ID NO 10213) '- CGG CAT GGC GGG CAC-3' (FRAG 835) (SEQ DD NO 10214) '- CGG CAT GGC GGG CA-3' (FRAG 836) (SEQ ID NO 10215) '- CGG CAT GGC GGG C-3' (FRAG 837) (SEQ DDNO 10216) '- CGG CAT GGC GGG -3' (FRAG 838) (SEQ DD NO 10217) '- CGG CAT GGC GG-3' (FRAG 839) (SEQ DDNO 10218) '- CGG CAT GGC G-3' (FRAG 840) (SEQ DD NO 10219) '- GG CAT GGC GGG CAC AGG C TG GGC-3' (FRAG 841) (SEQ DD NO 10220) '- GG CAT GGC GGG CAC AGG CTG GG-3' (FRAG 842) (SEQ DD NO 10221) '- GG CAT GGC GGG CAC AGG CTG G-3' (FRAG 843) (SEQ D NO 10222) '- GG CAT GGC GGG CAC AGG CTG -3' (FRAG 844) (SEQ ID NO 10223) '- GG CAT GGC GGG CAC AGG CT-3' (FRAG 845) (SEQ DD NO 10224) '- GG CAT GGC GGG CAC AGG C-3' (FRAG 846) (SEQ DD NO 10225) '- GG CAT GGC GGG CAC AGG -3' (FRAG 847) (SEQ DD NO 10226) '- GG CAT GGC GGG CAC AG-3' (FRAG 848) (SEQ DD NO 10227) '- GG CAT GGC GGG CAC A-3' (FRAG 849) (SEQ DD NO 10228) ' GG CAT GGC GGG CAC-3' (FRAG 850) (SEQ ID NO 10229) '- GG CAT GGC GGG CA-3' (FRAG 851) (SEQ DD NO 10230) '- GG CAT GGC GGG C-3' (FRAG 852) (SEQ DD NO 10231) '- GG CAT GGC GGG -3' (FRAG 853) (SEQ DD NO 10232) '- GG CAT GGC GG-3' (FRAG 854) (SEQ DD NO 10233) '- G CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 855) (SEQ DD NO 10234) '- G CAT GGC GGG CAC AGG CTG GG-3' (FRAG 856) (SEQ DD NO 10235) '- G CAT GGC GGG CAC AGG CTG G-3' (FRAG 857) (SEQ DD NO 10236) '- G CAT GGC GGG CAC AGG CTG -3' (FRAG 858) (SEQ ID NO 10237) '- G CAT GGC GGG CAC AGG CT-3' (FRAG 859) (SEQ DD NO 10238) '- G CAT GGC GGG CAC AGG C-3' (FRAG 860) (SEQ DD NO 10239) '- G CAT GGC GGG CAC AGG -3' (FRAG 861) (SEQ DD NO 10240) '- G CAT GGC GGG CAC AG-3' (FRAG 862) (SEQ DDNO 10241) '- G CAT GGC GGG CAC A-3' (FRAG 863) (SEQ DD NO 10242) '- G CAT GGC GGG CAC-3' (FRAG 864) (SEQ DD NO 10243) '- G CAT GGC GGG CA-3' (FRAG 865) (SEQ DD NO 10244) '- G CAT GGC GGG C-3' (FRAG 866) (SEQ ID NO 10245) '- G CAT GGC GGG -3' (FRAG 867) (SEQ TO NO 10246) '- CAT GGC GGG CAC AGG CTG GGC-3' (FRAG 868) (SEQ DD NO 10247) '- CAT GGC GGG CAC AGG CTG GG-3' (FRAG 869) (SEQ ED NO 10248) '- CAT GGC GGG CAC AGG CTG G-3' (FRAG 870) (SEQ ID NO 10249) '- CAT GGC GGG CAC AGG CTG -3' (FRAG 871) (SEQ DD NO 10250) '- CAT GGC GGG CAC AGG CT-3' (FRAG 872) (SEQ DD NO 10251) '- CAT GGC GGG CAC AGG C-3' (FRAG 873) (SEQ DD NO 10252) '- CAT GGC GGG CAC AGG -3' (FRAG 874) (SEQ ID NO 10253) '- CAT GGC GGG CAC AG-3' (FRAG 875) (SEQ DD NO 10254) 5'- CAT GGC GGG CAC A-3' (FRAG 876) (SEQ DD NO 10255)

5'- CAT GGC GGG CAC-3' (FRAG 877) (SEQ ID NO 10256)

5'- CAT GGC GGG CA-3' (FRAG 878) (SEQ DD NO 10257)

5'- CAT GGC GGG C-3' (FRAG 879) (SEQ DD NO 10258) 5'- AT GGC GGG CAC AGG CTG GGC-3' (FRAG 880) (SEQ ID NO 10259)

5'- AT GGC GGG CAC AGG CTG GG-3' (FRAG 881) (SEQ ED NO 10260)

5'- AT GGC GGG CAC AGG CTG G-3' (FRAG 882) (SEQ DD NO 10261)

5'- AT GGC GGG CAC AGG CTG -3' (FRAG 883) (SEQ DD NO 10262)

5'- AT GGC GGG CAC AGG CT-3' (FRAG 884) (SEQ DD NO 10263) 5'- AT GGC GGGCAC AGG C-3' (FRAG 885) (SEQ DD NO 10264)

5'- AT GGC GGG CAC AGG -3' (FRAG 886) (SEQ DD NO 10265)

5'- AT GGC GGG CAC AG-3' (FRAG 887) (SEQ DD NO 10266)

5'- AT GGC GGG CAC A-3' (FRAG 888) (SEQ ID NO 10267)

5'- AT GGC GGG CAC-3' (FRAG 889) (SEQ DD NO 10268) 5'- AT GGC GGG CA-3' (FRAG 890) (SEQ DD NO 10269)

5'- T GGC GGG CAC AGG CTG GGC-3' (FRAG 891) (SEQ ED NO 10270)

5'- T GGC GGG CAC AGG CTG GG-3' (FRAG 892) (SEQ ID NO 10271)

5'- T GGC GGG CAC AGG CTG G-3' (FRAG 893) (SEQ DD NO 10272)

5'- T GGC GGG CAC AGG CTG -3' (FRAG 894) (SEQ DD NO 10273) 5'- T GGC GGG CAC AGG CT-3' (FRAG 895) (SEQ DD NO 10274)

5'- T GGC GGG CAC AGG C-3' (FRAG 896) (SEQ DD NO 10275)

5'- T GGC GGG CAC AGG -3' (FRAG 897) (SEQ DD NO 10276)

5'- T GGC GGG CAC AG-3' (FRAG 898) (SEQ DD NO 10277)

5'- T GGC GGG CAC A-3' (FRAG 899) (SEQ DD NO 10278) 5'- T GGC GGG CAC-3' (FRAG 900) (SEQ DD NO 10279)

5'- GGC GGG CAC AGG CTG GGC-3' (FRAG 901) (SEQ DD NO 10280)

5'- GGC GGG CAC AGG CTG GG-3' (FRAG 902) (SEQ DD NO 10281)

5'- GGC GGG CAC AGG CTG G-3' (FRAG 903) (SEQ ID NO 10282)

5'- GGC GGG CAC AGG CTG -3' (FRAG 904) (SEQ DD NO 10283) 5'- GGC GGG CAC AGG CT-3' (FRAG 905) (SEQ ID NO 10284)

5'- GGC GGG CAC AGG C-3' (FRAG 906) (SEQ ID NO 10285)

5'- GGC GGG CAC AGG -3' (FRAG 907) (SEQ DD NO 10286)

5'- GGC GGG CAC AG-3' (FRAG 908) (SEQ DD NO 10287)

5'- GGC GGG CAC A-3' (FRAG 909) (SEQ ID NO 10288) 5'- GC GGG CAC AGG CTG GGC-3' (FRAG 910) (SEQ DDNO 10289)

5'- GC GGG CAC AGG CTG GG-3' (FRAG 911) (SEQ DD NO 10290)

5'- GC GGG CAC AGG CTG G-3' (FRAG 912) (SEQ DD NO 10291)

5'- GC GGG CAC AGG CTG -3' (FRAG 913) (SEQ DD NO 10292)

5'- GC GGG CAC AGG CT-3' (FRAG 914) (SEQ ID NO 10293) 5'- GC GGG CAC AGG C-3' (FRAG 915) (SEQ DD NO 10294)

5'- GC GGG CAC AGG -3' (FRAG 16) (SEQ ID NO 10295)

5'- GC GGG CAC AG-3' (FRAG 917) (SEQ ED NO 10296)

5'- C GGG CAC AGG CTG GGC-3' (FRAG 918) (SEQ ED NO 10297)

5'- GGG CAC AGG CTG GG-3' (FRAG 919) (SEQ DD NO 10298) 5'- C GGG CAC AGG CTG G-3' (FRAG 920) (SEQ DD NO 10299)

5'- C GGG CAC AGG CTG -3' (FRAG 921) (SEQ ID NO 10300)

5'- C GGG CAC AGG CT-3' (FRAG 922) (SEQ ID NO 10301)

5'- C GGG CAC AGG C-3' (FRAG 923) (SEQ ID NO 10302)

5'- C GGG CAC AGG -3' (FRAG 924) (SEQ ID NO 10303) 5'- GGG CAC AGG CTG GGC-3' (FRAG 925) (SEQ ID NO 10304)

5'- GGG CAC AGG CTG GG-3' (FRAG 926) (SEQ DD NO 10305)

5'- GGG CAC AGG CTG G-3' (FRAG 927) (SEQ ID NO 10306)

5'- GGG CAC AGG CTG -3' (FRAG 928) (SEQ DD NO 10307)

5'- GGG CAC AGG CT-3' (FRAG 929) (SEQ DD NO 10308) 5'- GGG CAC AGG C-3' (FRAG 930) (SEQ DD NO 10309)

5'- GG CAC AGG CTG GGC-3' (FRAG 931) (SEQ DD NO 10310)

5'- GG CAC AGG CTG GG-3' (FRAG 932) (SEQ DD NO 10311)

5'- GG CAC AGG CTG G-3' (FRAG 933) (SEQ DD NO 10312)

5'-GG CAC AGG CTG -3' (FRAG 934) (SEQ DDNO 10313) 5'- GG CAC AGG CT-3' (FRAG 935) (SEQ ID NO 10314)

5'-G CAC AGG CTG GGC-3' (FRAG 936) (SEQ DD NO 10315)

5'-G CAC AGG CTG GG-3' (FRAG 937) (SEQ DD NO 10316)

5'-G CAC AGG CTG G-3' (FRAG 938) (SEQ ID NO 10317)

5'-G CAC AGG CTG -3' (FRAG 939) (SEQ DD NO 10318) 5'-CAC AGG CTG GGC-3' (FRAG 940) (SEQ DD NO 10319)

5'-CAC AGG CTG GG-3' (FRAG 941) (SEQ DDNO 10320)

5'-CAC AGG CTG G-3' (FRAG 942) (SEQ DD NO 10321)

5'-AC AGG CTG GGC-3' (FRAG 943) (SEQ DD NO 10322)

5'-AC AGG CTG GG-3' (FRAG 944) (SEQ ID NO 10323) 5'-C AGG CTG GGC-3' (FRAG 945) (SEQ ED NO 10324)

5'-TTT TCC TTC CTT TGT CTC TCT TC (FRAG 946) (SEQ DD NO 10325)

5'-GCT CCC GGC TGC CTG (FRAG 947) (SEQ ID NO 10326)

5' CTC GGC CGT GCG GCT CTG TCG CTC CCG GT (FRAG 948) (SEQ DD NO 10327)

5'-CCG CCG CCC TCC GGG GGG TC (FRAG 949) (SEQ DD NO 10328) 5'-TGC TGC CGT TGG CTG CCC (FRAG 950) (SEQ DDNO 10329)

5'-CTT CTG CGG GTC GCC GG (FRAG 951) (SEQ DD NO 10330)

5'-TGC TGG GCT TGT GGC (FRAG 952) (SEQ DD NO 10331)

5'-GGC CTC TCT TCT GGG (FRAG 953) (SEQ DD NO 10332)

5'-CCT GGT CCC TCC GT (FRAG 954) (SEQ DD NO 10333) 5'-GGT GGC TCC TCT GC (FRAG 955) (SEQ DD NO 10334)

5'-GCT TGG TCC TGG GGC TGC (FRAG 956) (SEQ ID NO 10335)

5'-TGC TCT CCT CTC CTT (FRAG 957) (SEQ ED NO 10336)

Human Adenosine A _st Receptor Nucleic Acid and Antisense Oligonucleotide Fragments

5'-TGC TTT TCT TTT CTG GGC CTC TGT GGT CTG TTT TTT TCT G GCC CTG CTG GGG CGC TCT CC GCC GCC CGC CTG GCT CCC GGB GCC CBT GBT GGG CBT GCC GTG GTT CTT GCC CTC CTT TGG CTG CCG TGC CCG CTC CCC GGC CTC CTG GCG GGT GGC CGT TG GGC CCG TGT TCC CCT GGG -GCC TGG GGC TCC CTT CTC TC

GCC CTT CTT GCT GGG CCT C TGC TGC TGC TGG TGC TGT GGC CCC C GTA CAC CGA GGA GCC CAT GAT GGG CAT GCC ACA GAC GAC AGG C GTB CBC CGB GGB

GCC CBT GBT GGG CBT GCC BCB GBC GBC BGG C-3' (FRAG NO 1665) (SEQ D NO 11049)

5'-CTG GGC CTC-3' (FRAG 1666) (SEQ DDNO 11050)

5'-TGC TTT TCT TTT CTG GGC CTC-3' (FRAG 958) (SEQ DD NO 10337) 5'-TGT GGT CTG TTT TTT TCT G-3' (FRAG 959) (SEQ ED NO 10338)

5'-GCC CTG CTG GGG CGC TCT CC-3' (FRAG 960) (SEQ DD NO 10339)

5'-GCC GCC CGC CTG GCT CCC-3' (FRAG 961) (SEQ DD NO 10340)

5'-GGB GCC CBT GBT GGG CBT GCC-3' (FRAG 962) (SEQ DD NO 10341)

5'-GTG GTT CTT GCC CTC CTT TGG CTG-3' (FRAG 963) (SEQ TD NO 10342) 5'-CCG TGC CCG CTC CCC GGC-3 ' (FRAG 964) (SEQ DD NO 10343)

5'-CTC CTG GCG GGT GGC CGT TG-3' (FRAG 965) (SEQ DD NO 10344)

5'-GGC CCG TGT TCC CCT GGG-3' (FRAG 966) (SEQ DDNO 10345)

5'-GCC TGG GGC TCC CTT CTC TC-3' (FRAG 967) (SEQ DD NO 10346)

5'-GCC CTT CTT GCT GGG CCT C-3 ' (FRAG 968) (SEQ DD NO 10347) ' 5'-TGC TGC TGC TGG TGC TGT GGC CCC C-3' (FRAG 969) (SEQ DD NO 10348)

5'-GTACACCGAGGAGCCCATGATGGGCATGCCACAGACGACAGGC-3' (FRAG 970) (SEQ DD NO 10349) 5'-GTBCBCCGBGGBGCCCBTGBTGGGCBTGCCBCBGBCGBCBGGC-3' (FRAG 971) (SEQ DD NO 10350)

Human Adenosine A?_h Receptor Nucleic Acid & Antisense Oligonucleotide Fragments 5'-GGC GCC GTG CCG CGT CTT GGT GGC GGC GG GTT CGC GCC CGC GCG GGG CCC CTC CGG TCC GTT CGC GCC CGC GCG GGG CCC CTC CGG TCC CGG GTC GGG

GCC CCC CGC GGC C GCC TCG GGG CTG GGG CGC TGG TGG CCG GG CCG CGC CTC CGC CTG CCG CTT CTG GCT GGG CCC CGG GCG CCC CCT CCC CTC TTG CTC GGG TCC CCG TG ACA GCG CGT CCT GTG TCT CCA GCA GCA TGG CCG GGC CAG CTG GGC CCC BCB GCG CGT CCT GTG TCT CCB GCB GCB TGG CCG GGC CBG CTG GGC CCC CCCAGCCCCG AGGCTCAGAA GCGGCAGGCG GAGGCGCGGT CCGGGCGCTA TGGCCATGCC CGGCGGGTCT CACGCGGCTG CCCCTCGCCC GGCGCGCCTT CGGTAGGGGG CGCCCGGGGC CCAGCTGGCC CGGCCATGCT GCTGGAGACA CAGGACGCGC TGTACGTGGC GCTGGAGCTG GTCATCGCCG CGCTTTCGGT GGCGGGCAAC GTGCTGGTGT GCGCCGCGGT GGGCACGGCG AACACTCTGC AGACGCCCAC CAACTACTTC CTGGTGTCCC TGGCTGCGGC CGACGTGGCC GTGGGGCTCT

TCGCCATCCC CTTTGCCATC ACCATCAGCC TGGGCTTCTG CACTGACTTC TACGGCTGCC TCTTCCTCGC CTGCTTCGTG CTGGTGCTCA CGCAGAGCTC CATCTTCAGC CTTCTGGCCG TGGCAGTCGA CAGATACCTG GCCATCTGTG TCCCGCTCAG GTATAAAAGT TTGGTCACGG GGACCCGAGC AAGAGGGGTC ATTGCTGTCC TCTGGGTCCT TGCCTTTGGC ATCGGATTGA CTCCATTCCT GGGGTGGAAC AGTAAAGACA GTGCCACCAA CAACTGCACA GAACCCTGGG ATGGAACCAC GAATGAAAGC TGCTGCCTTG TGAAGTGTCT CTTTGAGAAT GTGGTCCCCA TGAGCTACAT GGTATATTTC AATTTCTTTG GGTGTGTTCT GCCCCCACTG CTTATAATGC TGGTGATCTA CATTAAGATC TTCCTGGTGG CCTGCAGGCA GCTTCAGCGC ACTGAGCTGA TGGACCACTC GAGGACCACC CTCCAGCGGG AGATCCATGC AGCCAAGTCA CTGGCCATGA TTGTGGGGAT

TTTTGCCCTG TGCTGGTTAC CTGTGCATGC TGTTAACTGT GTCACTCTTT TCCAGCCAGC TCAGGGTAAA AATAAGCCCA AGTGGGCAAT GAATATGGCC ATTCTTCTGT CACATGCCAA TTCAGTTGTC AATCCCATTG TCTATGCTTA CCGGAACCGA GACTTCCGCT ACACTTTTCA CAAAATTATC TCCAGGTATC TTCTCTGCCA AGCAGATGTC AAGAGTGGGA ATGGTCAGGC TGGGGTACAG CCTGCTCTCG GTGTGGGCCT ATGATCTAGG CTCTCGCCTC TTCCAGGAGA AGATACAAAT CCACAAGAAA CAAAGAGGAC ACGGCTGGTT TTCATTGTGA AAGATAGCTA CACCTCACAA GGAAATGGAC TGCCTCTCTT GAGCACTTCC CTGGAGCTAC CACGTATCTA GCTAATATGT ATGTGTCAGT AGTAGCACCA AGGATTGACA AATATATTTA TGATCTATTC AGCTGCTTTT ACTGTGTGGA TTATGCCAAC AGCTTGAATG GATTCTAACA GACTCTTTTG TTTTTAAAAG

TCTGCCTTGT TTATGGTGGA AAATTACTGA AACTATTTTA CTGTGAAACA GTGTGAACTA TTATAATGCA AATACTTTTT AACTTAGAGG CAATGGAAAA ATAAAAGTTG ACTGTACTAA AAATGTATAC TTGTTGCCAG GAAGGTGACC TCAAAAATTA AAAGTATAAT TATTCGGCCG GGCATGGTGG CTCACACCTG TAATTCCAGC ACTTTGGGAG GCCAAGGCAG GCGGATCACG AGGTCAGGAG TTCAAAACCA GCCTGTCCAA TATAGTG GGGCAATTTG TTAGTTATCC GCCGCCACCA AGACGCGGCA CGGCGCCTGG ACCGGAGGGG CCCCGCGCGG GCGCGAACTT TGGGCTCGGG CGAGTGGGTG GTGCTCCGCC CAGCCCGAGA CGGGCGGGCG CGCGGGCCAA TGGGTGCCGC CTCTTGGCCG CGGGGGGCCC CGACCCGTGG GTCCCGGCCA CCAGCGCCCC AGCCCCGAGG CTCAGAAGCG GCAGGCGGAG GCGCGGTCCG GGCGCTATGG

CCATGCCCGG CGGGTCTCAC GCGGCTGCCC CTCGCCCGGC GCGCCTTCGG TAGGGGGCGC CCGGGGCCCA GCTGGCCCGG CCATGCTGCT GGAGACACAG GACGCGCTGT ACGTGGCGCT GGAGCTGGTC ATCGCCGCGC TTTCGGTGGC GGGCAACGTG CTGGTGTGCG CCGCGGTGGG CACGGCGAAC ACTCTGCAGA CGCCCACCAA CTACTTCCTG GTGTCCCTGG CTGCGGCCGA CGTGGCCGTG GGGCTCTTCG CCATCCCCTT TGCCATCACC ATCAGCCTGG GCTTCTGCAC TGACTTCTAC GGCTGCCTCT TCCTCGCCTG CTTCGTGCTG GTGCTCACGC AGAGCTCCAT CTTCAGCCTT CTGGCGGTGG CAGTCGACAG ATACCTGGCC ATCTGTGTCC CGCTCAGGTA TAAAAGTTTG GTCACGGGGA CCCGAGCAAG AGGGGTCATT GCTGTCCTCT GGGTCCTTGC CTTTGGCATC GGATTGACTC CATTCCTGGG GTGGAACAGT AAAGACAGTG CCACCAACAA CTGCACAGAA

CCCTGGGATG GAACCACGAA TGAAAGCTGC TGCCTTGTGA AGTGTCTCTT TGAGAATGTG GTCCCCATGA GCTACATGGT ATATTTCAAT TTCTTTGGGT GTGTTCTGCC CCCACTGCTT ATAATGCTGG TGATCTACAT TAAGATCTTC CTGGTGGCCT GCAGGCAGCT TCAGCGCACT GAGCTGATGG ACCACTCGAG GACCACCCTC CAGCGGGAGA TCCATGCAGC CAAGTCACTG GCCATGATTG TGGGGATTTT TGCCCTGTGC TGGTTACCTG TGCATGCTGT TAACTGTGTC ACTCTTTTCC AGCCAGCTCA GGGTAAAAAT AAGCCCAAGT GGGCAATGAA TATGGCCATT CTTCTGTCAC ATGCCAATTC AGTTGTCAAT CCCATTGTCT ATGCTTACCG GAACCGAGAC TTCCGCTACA CTTTTCACAA AATTATCTCC AGGTATCTTC TCTGCCAAGC AGATGTCAAG AGTGGGAATG GTCAGGCTGG GGTACAGCCT GCTCTCGGTG TGGGCCTATG ATCTAGGCTC TCGCCTCTTC

CAGGAGAAGA TACAAATCCA CAAGAAACAA AGAGGACACG GCTGGTTTTC ATTGTGAAAG ATAGCTACAC CTCACAAGGA AATGGACTGC CTCTCTTGAG CACTTCCCTG GAGCTACCAC GTATCTAGCT AATATGTATG TGTCAGTAGT AGGCTCCAAG GATTGACAAA TATATTTATG ATCTATTCAG CTGCTTTTAC TGTGTGGATT ATGCCAACAG CTTGAATGGA TTCTAACAGA CTCTTTTGTT TTTAAAAGTC TGCCTTGTTT ATGGTGGAAA ATTACTGAAA CTATTTTACT GTGAAACAGT GTGAACTATT ATAATGCAAA TACTTTTTAA CTTAGAGGCA ATGGAAAAAT AAAAGTTGAC TGTACTAAAA ATG CCCAGCCCCG AGGCTCAGAA GCGGCAGGCG GAGGCGCGGT CCGGGCGCTA TGGCCATGCC CGGCGGGTCT CACGCGGCTG CCCCTCGCCC GGCGCGCCTT CGGTAGGGGG CGCCCGGGGC CCAGCTGGCC CGGCCATGCT GCTGGAGACA

CAGGACGCGC TGTACGTGGC GCTGGAGCTG GTCATCGCCG CGCTTTCGGT GGCGGGCAAC GTGCTGGTGT GCGCCGCGGT GGGCACGGCG AACACTCTGC AGACGCCCAC CAACTACTTC CTGGTGTCCC TGGCTGCGGC CGACGTGGCC GTGGGGCTCT TCGCCATCCC CTTTGCCATC ACCATCAGCC TGGGCTTCTG CACTGACTTC TACGGCTGCC TCTTCCTCGC CTGCTTCGTG CTGGTGCTCA CGCAGAGCTC CATCTTCAGC CTTCTGGCCG TGGCAGTCGA CAGATACCTG GCCATCTGTG TCCCGCTCAG GTATAAAAGT TTGGTCACGG GGACCCGAGC AAGAGGGGTC ATTGCTGTCC TCTGGGTCCT TGCCTTTGGC ATCGGATTGA CTCCATTCCT GGGGTGGAAC AGTAAAGACA GTGCCACCAA CAACTGCACA GAACCCTGGG ATGGAACCAC GAATGAAAGC TGCTGCCTTG TGAAGTGTCT CTTTGAGAAT GTGGTCCCCA TGAGCTACAT GGTATATTTC AATTTCTTTG

GGTGTGTTCT GCCCCCACTG CTTATAATGC TGGTGATCTA CATTAAGATC TTCCTGGTGG CCTGCAGGCA GCTTCAGCGC ACTGAGCTGA TGGACCACTC GAGGACCACC CTCCAGCGGG AGATCCATGC AGCCAAGTCA CTGGCCATGA TTGTGGGGAT TTTTGCCCTG TGCTGGTTAC CTGTGCATGC TGTTAACTGT GTCACTCTTT TCCAGCCAGC TCAGGGTAAA AATAAGCCCA AGTGGGCAAT GAATATGGCC ATTCTTCTGT CACATGCCAA TTCAGTTGTC AATCCCATTG TCTATGCTTA CCGGAACCGA GACTTCCGCT ACACTTTTCA CAAAATTATC TCCAGGTATC TTCTCTGCCA AGCAGATGTC AAGAGTGGGA ATGGTCAGGC TGGGGTACAG CCTGCTCTCG GTGTGGGCCT ATGATCTAGG CTCTCGCCTC TTCCAGGAGA AGATACAAAT CCACAAGAAA CAAAGAGGAC ACGGCTGGTT TTCATTGTGA AAGATAGCTA CACCTCACAA GGAAATGGAC TGCCTCTCTT

GAGCACTTCC CTGGAGCTAC CACGTATCTA GCTAATATGT ATGTGTCAGT AGTAGCACCA AGGATTGACA AATATATTTA TGATCTATTC AGCTGCTTTT ACTGTGTGGA TTATGCCAAC AGCTTGAATG GATTCTAACA GACTCTTTTG TTTTTAAAAG TCTGCCTTGT TTATGGTGGA AAATTACTGA AACTATTTTA CTGTGAAACA GTGTGAACTA TTATAATGCA AATACTTTTT AACTTAGAGG CAATGGAAAA ATAAAAGTTG ACTGTACTAA AAATGTATAC TTGTTGCCAG GAAGGTGACC TCAAAAATTA AAAGTATAAT TATTCGGCCG GGCATGGTGG CTCACACCTG TAATTCCAGC ACTTTGGGAG GCCAAGGCAG GCGGATCACG AGGTCAGGAG TTCAAAACCA GCCTGTCCAA TATAGTG GGGCAATTTG TTAGTTATCC GCCGCCACCA AGACGCGGCA CGGCGCCTGG ACCGGAGGGG CCCCGCGCGG GCGCGAACTT TGGGCTCGGG CGAGTGGGTG

GTGCTCCGCC CAGCCCGAGA CGGGCGGGCG CGCGGGCCAA TGGGTGCCGC CTCTTGGCCG CGGGGGGCCC CGACCCGTGG GTCCCGGCCA CCAGCGCCCC AGCCCCGAGG CTCAGAAGCG GCAGGCGGAG GCGCGGTCCG GGCGCTATGG CCATGCCCGG CGGGTCTCAC GCGGCTGCCC CTCGCCCGGC GCGCCTTCGG TAGGGGGCGC CCGGGGCCCA GCTGGCCCGG CCATGCTGCT GGAGACACAG GACGCGCTGT ACGTGGCGCT GGAGCTGGTC ATCGCCGCGC TTTCGGTGGC GGGCAACGTG CTGGTGTGCG CCGCGGTGGG CACGGCGAAC ACTCTGCAGA CGCCCACCAA CTACTTCCTG GTGTCCCTGG CTGCGGCCGA CGTGGCCGTG GGGCTCTTCG CCATCCCCTT TGCCATCACC ATCAGCCTGG GCTTCTGCAC TGACTTCTAC GGCTGCCTCT TCCTCGCCTG CTTCGTGCTG GTGCTCACGC AGAGCTCCAT CTTCAGCCTT

CTGGCCGTGG CAGTCGACAG ATACCTGGCC ATCTGTGTCC CGCTCAGGTA TAAAAGTTTG GTCACGGGGA CCCGAGCAAG AGGGGTCATT GCTGTCCTCT GGGTCCTTGC CTTTGGCATC GGATTGACTC CATTCCTGGG GTGGAACAGT AAAGACAGTG CCACCAACAA CTGCACAGAA CCCTGGGATG GAACCACGAA TGAAAGCTGC TGCCTTGTGA AGTGTCTCTT TGAGAATGTG GTCCCCATGA GCTACATGGT ATATTTCAAT TTCTTTGGGT GTGTTCTGCC CCCACTGCTT ATAATGCTGG TGATCTACAT TAAGATCTTC CTGGTGGCCT GCAGGCAGCT TCAGCGCACT GAGCTGATGG ACCACTCGAG GACCACCCTC CAGCGGGAGA TCCATGCAGC CAAGTCACTG GCCATGATTG TGGGGATTTT TGCCCTGTGC TGGTTACCTG TGCATGCTGT TAACTGTGTC ACTCTTTTCC AGCCAGCTCA GGGTAAAAAT AAGCCCAAGT GGGCAATGAA TATGGCCATT CTTCTGTCAC

ATGCCAATTC AGTTGTCAAT CCCATTGTCT ATGCTTACCG GAACCGAGAC TTCCGCTACA CTTTTCACAA AATTATCTCC AGGTATCTTC TCTGCCAAGC AGATGTCAAG AGTGGGAATG GTCAGGCTGG GGTACAGCCT GCTCTCGGTG TGGGCCTATG ATCTAGGCTC TCGCCTCTTC CAGGAGAAGA TACAAATCCA CAAGAAACAA AGAGGACACG GCTGGTTTTC ATTGTGAAAG ATAGCTACAC CTCACAAGGA AATGGACTGC CTCTCTTGAG CACTTCCCTG GAGCTACCAC GTATCTAGCT AATATGTATG TGTCAGTAGT AGGCTCCAAG GATTGACAAA TATATTTATG ATCTATTCAG CTGCTTTTAC TGTGTGGATT ATGCCAACAG CTTGAATGGA TTCTAACAGA CTCTTTTGTT TTTAAAAGTC TGCCTTGTTT ATGGTGGAAA ATTACTGAAA CTATTTTACT GTGAAACAGT GTGAACTATT ATAATGCAAA TACTTTTTAA CTTAGAGGCA ATGGAAAAAT AAAAGTTGAC

TGTACTAAAA ATG -3' (FRAG NO 1670) (SEQ DDNO 12375)

5'- GGGCAATTTG TTAGTTATCC GCCGCCACCA AGACGCGGCA CGGCGCCTGG ACCGGAGGGG CCCCGCGCGG GCGCGAACTT TGGGCTCGGG CGAGTGGGTG GTGCTCCGCC CAGCCCGAGA CGGGCGGGCG CGCGGGCCAA TGGGTGCCGC CTCTTGGCCG CGGGGGGCCC CGACCCGTGG GTCCCGGCCA CCAGCGCCCC AGCCCCGAGG CTCAGAAGCG GCAGGCGGAG GCGCGGTCCG GGCGCTATGG CCATGCCCGG CGGGTCTCAC GCGGCTGCCC CTCGCCCGGC GCGCCTTCGG TAGGGGGCGC CCGGGGCCCA GCTGGCCCGG CCATGCTGCT GGAGACACAG GACGCGCTGT ACGTGGCGCT GGAGCTGGTC ATCGCCGCGC TTTCGGTGGC

GGGCAACGTG CTGGTGTGCG CCGCGGTGGG CACGGCGAAC ACTCTGCAGA CGCCCACCAA CTACTTCCTG GTGTCCCTGG CTGCGGCCGA CGTGGCCGTG GGGCTCTTCG CCATCCCCTT TGCCATCACC ATCAGCCTGG GCTTCTGCAC TGACTTCTAC GGCTGCCTCT TCCTCGCCTG CTTCGTGCTG GTGCTCACGC AGAGCTCCAT CTTCAGCCTT CTGGCCGTGG CAGTCGACAG ATACCTGGCC ATCTGTGTCC CGCTCAGGTA TAAAAGTTTG GTCACGGGGA CCCGAGCAAG AGGGGTCATT GCTGTCCTCT GGGTCCTTGC CTTTGGCATC GGATTGACTC CATTCCTGGG GTGGAACAGT AAAGACAGTG CCACCAACAA CTGCACAGAA CCCTGGGATG GAACCACGAA TGAAAGCTGC TGCCTTGTGA AGTGTCTCTT TGAGAATGTG GTCCCCATGA GCTACATGGT ATATTTCAAT TTCTTTGGGT GTGTTCTGCC CCCACTGCTT ATAATGCTGG TGATCTACAT TAAGATCTTC

CTGGTGGCCT GCAGGCAGCT TCAGCGCACT GAGCTGATGG ACCACTCGAG GACCACCCTC CAGCGGGAGA TCCATGCAGC CAAGTCACTG GCCATGATTG TGGGGATTTT TGCCCTGTGC TGGTTACCTG TGCATGCTGT TAACTGTGTC ACTCTTTTCC AGCCAGCTCA GGGTAAAAAT AAGCCCAAGT GGGCAATGAA TATGGCCATT CTTCTGTCAC ATGCCAATTC AGTTGTCAAT CCCATTGTCT ATGCTTACCG GAACCGAGAC TTCCGCTACA CTTTTCACAA AATTATCTCC AGGTATCTTC TCTGCCAAGC AGATGTCAAG AGTGGGAATG GTCAGGCTGG GGTACAGCCT GCTCTCGGTG TGGGCCTATG ATCTAGGCTC TCGCCTCTTC CAGGAGAAGA TACAAATCCA CAAGAAACAA AGAGGACACG GCTGGTTTTC ATTGTGAAAG ATAGCTACAC CTCACAAGGA AATGGACTGC CTCTCTTGAG CACTTCCCTG GAGCTACCAC GTATCTAGCT AATATGTATG TGTCAGTAGT

AGGCTCCAAG GATTGACAAA TATATTTATG ATCTATTCAG CTGCTTTTAC TGTGTGGATT ATGCCAACAG CTTGAATGGA TTCTAACAGA CTCTTTTGTT TTTAAAAGTC TGCCTTGTTT ATGGTGGAAA ATTACTGAAA CTATTTTACT GTGAAACAGT GTGAACTATT ATAATGCAAA TACTTTTTAA CTTAGAGGCA ATGGAAAAAT AAAAGTTGAC TGTACTAAAA ATG-3'(FRAG NO J(SEQ DD NO 11805) 5'-CCCAGCCCCG AGGCTCAGAA GCGGCAGGCG GAGGCGCGGT CCGGGCGCTA TGGCCATGCC CGGCGGGTCT CACGCGGCTG CCCCTCGCCC GGCGCGCCTT CGGTAGGGGG CGCCCGGGGC CCAGCTGGCC CGGCCATGCT GCTGGAGACA CAGGACGCGC TGTACGTGGC GCTGGAGCTG GTCATCGCCG CGCTTTCGGT

GGCGGGCAAC GTGCTGGTGT GCGCCGCGGT GGGCACGGCG AACACTCTGC AGACGCCCAC CAACTACTTC CTGGTGTCCC TGGCTGCGGC CGACGTGGCC GTGGGGCTCT TCGCCATCCC CTTTGCCATC ACCATCAGCC TGGGCTTCTG CACTGACTTC TACGGCTGCC TCTTCCTCGC CTGCTTCGTG CTGGTGCTCA CGCAGAGCTC CATCTTCAGC CTTCTGGCCG TGGCAGTCGA CAGATACCTG GCCATCTGTG TCCCGCTCAG GTATAAAAGT TTGGTCACGG GGACCCGAGC AAGAGGGGTC ATTGCTGTCC TCTGGGTCCT TGCCTTTGGC ATCGGATTGA CTCCATTCCT GGGGTGGAAC AGTAAAGACA GTGCCACCAA CAACTGCACA GAACCCTGGG ATGGAACCAC GAATGAAAGC TGCTGCCTTG TGAAGTGTCT CTTTGAGAAT GTGGTCCCCA TGAGCTACAT GGTATATTTC AATTTCTTTG GGTGTGTTCT GCCCCCACTG CTTATAATGC TGGTGATCTA CATTAAGATC

TTCCTGGTGG CCTGCAGGCA GCTTCAGCGC ACTGAGCTGA TGGACCACTC GAGGACCACC CTCCAGCGGG AGATCCATGC AGCCAAGTCA CTGGCCATGA TTGTGGGGAT TTTTGCCCTG TGCTGGTTAC CTGTGCATGC TGTTAACTGT GTCACTCTTT TCCAGCCAGC TCAGGGTAAA AATAAGCCCA AGTGGGCAAT GAATATGGCC ATTCTTCTGT CACATGCCAA TTCAGTTGTC AATCCCATTG TCTATGCTTA CCGGAACCGA GACTTCCGCT ACACTTTTCA CAAAATTATC TCCAGGTATC TTCTCTGCCA AGCAGATGTC AAGAGTGGGA ATGGTCAGGC TGGGGTACAG CCTGCTCTCG GTGTGGGCCT ATGATCTAGG CTCTCGCCTC TTCCAGGAGA AGATACAAAT CCACAAGAAA CAAAGAGGAC ACGGCTGGTT TTCATTGTGA AAGATAGCTA CACCTCACAA GGAAATGGAC TGCCTCTCTT GAGCACTTCC CTGGAGCTAC CACGTATCTA GCTAATATGT ATGTGTCAGT AGTAGCACCA AGGATTGACA AATATATTTA TGATCTATTC AGCTGCTTTT ACTGTGTGGA TTATGCCAAC AGCTTGAATG GATTCTAACA GACTCTTTTG TTTTTAAAAG TCTGCCTTGT TTATGGTGGA AAATTACTGA AACTATTTTA CTGTGAAACA GTGTGAACTA TTATAATGCA AATACTTTTT AACTTAGAGG CAATGGAAAA ATAAAAGTTG ACTGTACTAA AAATGTATAC TTGTTGCCAG GAAGGTGACC TCAAAAATTA AAAGTATAAT TATTCGGCCG GGCATGGTGG CTCACACCTG TAATTCCAGC ACTTTGGGAG GCCAAGGCAG GCGGATCACG AGGTCAGGAG TTCAAAACCA GCCTGTCCAA TATAGTG -3' (FRAG NO J (SEQ DD NO 11804)

5'- GGGCAATTTG TTAGTTATCC GCCGCCACCA AGACGCGGCA CGGCGCCTGG ACCGGAGGGG CCCCGCGCGG GCGCGAACTT TGGGCTCGGG CGAGTGGGTG GTGCTCCGCC CAGCCCGAGA CGGGCGGGCG CGCGGGCCAA TGGGTGCCGC CTCTTGGCCG CGGGGGGCCC CGACCCGTGG GTCCCGGCCA CCAGCGCCCC AGCCCCGAGG CTCAGAAGCG GCAGGCGGAG GCGCGGTCCG GGCGCTATGG CCATGCCCGG CGGGTCTCAC GCGGCTGCCC CTCGCCCGGC GCGCCTTCGG TAGGGGGCGC CCGGGGCCCA GCTGGCCCGG CCATGCTGCT GGAGACACAG GACGCGCTGT ACGTGGCGCT GGAGCTGGTC ATCGCCGCGC TTTCGGTGGC GGGCAACGTG CTGGTGTGCG CCGCGGTGGG CACGGCGAAC ACTCTGCAGA CGCCCACCAA CTACTTCCTG GTGTCCCTGG CTGCGGCCGA CGTGGCCGTG GGGCTCTTCG

CCATCCCCTT TGCCATCACC ATCAGCCTGG GCTTCTGCAC TGACTTCTAC GGCTGCCTCT TCCTCGCCTG CTTCGTGCTG GTGCTCACGC AGAGCTCCAT CTTCAGCCTT CTGGCCGTGG CAGTCGACAG ATACCTGGCC ATCTGTGTCC CGCTCAGGTA TAAAAGTTTG GTCACGGGGA CCCGAGCAAG AGGGGTCATT GCTGTCCTCT GGGTCCTTGC CTTTGGCATC GGATTGACTC CATTCCTGGG GTGGAACAGT AAAGACAGTG CCACCAACAA CTGCACAGAA CCCTGGGATG GAACCACGAA TGAAAGCTGC TGCCTTGTGA AGTGTCTCTT TGAGAATGTG GTCCCCATGA GCTACATGGT ATATTTCAAT TTCTTTGGGT GTGTTCTGCC CCCACTGCTT ATAATGCTGG TGATCTACAT TAAGATCTTC CTGGTGGCCT GCAGGCAGCT TCAGCGCACT GAGCTGATGG ACCACTCGAG GACCACCCTC CAGCGGGAGA TCCATGCAGC CAAGTCACTG GCCATGATTG TGGGGATTTT

TGCCCTGTGC TGGTTACCTG TGCATGCTGT TAACTGTGTC ACTCTTTTCC AGCCAGCTCA GGGTAAAAAT AAGCCCAAGT GGGCAATGAA TATGGCCATT CTTCTGTCAC ATGCCAATTC AGTTGTCAAT CCCATTGTCT ATGCTTACCG GAACCGAGAC TTCCGCTACA CTTTTCACAA AATTATCTCC AGGTATCTTC TCTGCCAAGC AGATGTCAAG AGTGGGAATG GTCAGGCTGG GGTACAGCCT GCTCTCGGTG TGGGCCTATG ATCTAGGCTC TCGCCTCTTC CAGGAGAAGA TACAAATCCA CAAGAAACAA AGAGGACACG GCTGGTTTTC ATTGTGAAAG ATAGCTACAC CTCACAAGGA AATGGACTGC CTCTCTTGAG CACTTCCCTG GAGCTACCAC GTATCTAGCT AATATGTATG TGTCAGTAGT AGGCTCCAAG GATTGACAAA TATATTTATG ATCTATTCAG CTGCTTTTAC TGTGTGGATT ATGCCAACAG CTTGAATGGA TTCTAACAGA CTCTTTTGTT TTTAAAAGTC

TGCCTTGTTT ATGGTGGAAA ATTACTGAAA CTATTTTACT GTGAAACAGT GTGAACTATT ATAATGCAAA TACTTTTTAA CTTAGAGGCA ATGGAAAAAT AAAAGTTGAC TGTACTAAAA ATG-3'(FRAG NO _)(SEQ ID NO 11794)

5'-CCCAGCCCCG AGGCTCAGAA GCGGCAGGCG GAGGCGCGGT CCGGGCGCTA TGGCCATGCC CGGCGGGTCT CACGCGGCTG CCCCTCGCCC GGCGCGCCTT CGGTAGGGGG CGCCCGGGGC CCAGCTGGCC CGGCCATGCT GCTGGAGACA CAGGACGCGC TGTACGTGGC GCTGGAGCTG GTCATCGCCG CGCTTTCGGT GGCGGGCAAC GTGCTGGTGT GCGCCGCGGT GGGCACGGCG AACACTCTGC AGACGCCCAC CAACTACTTC CTGGTGTCCC TGGCTGCGGC CGACGTGGCC GTGGGGCTCT

TCGCCATCCC CTTTGCCATC ACCATCAGCC TGGGCTTCTG CACTGACTTC TACGGCTGCC TCTTCCTCGC CTGCTTCGTG CTGGTGCTCA CGCAGAGCTC CATCTTCAGC CTTCTGGCCG TGGCAGTCGA CAGATACCTG GCCATCTGTG TCCCGCTCAG GTATAAAAGT TTGGTCACGG GGACCCGAGC AAGAGGGGTC ATTGCTGTCC TCTGGGTCCT TGCCTTTGGC ATCGGATTGA CTCCATTCCT GGGGTGGAAC AGTAAAGACA GTGCCACCAA CAACTGCACA GAACCCTGGG ATGGAACCAC GAATGAAAGC TGCTGCCTTG TGAAGTGTCT CTTTGAGAAT GTGGTCCCCA TGAGCTACAT GGTATATTTC AATTTCTTTG GGTGTGTTCT GCCCCCACTG CTTATAATGC TGGTGATCTA CATTAAGATC TTCCTGGTGG CCTGCAGGCA GCTTCAGCGC ACTGAGCTGA TGGACCACTC GAGGACCACC CTCCAGCGGG AGATCCATGC AGCCAAGTCA CTGGCCATGA TTGTGGGGAT

TTTTGCCCTG TGCTGGTTAC CTGTGCATGC TGTTAACTGT GTCACTCTTT TCCAGCCAGC TCAGGGTAAA AATAAGCCCA AGTGGGCAAT GAATATGGCC ATTCTTCTGT CACATGCCAA TTCAGTTGTC AATCCCATTG TCTATGCTTA CCGGAACCGA GACTTCCGCT ACACTTTTCA CAAAATTATC TCCAGGTATC TTCTCTGCCA AGCAGATGTC AAGAGTGGGA ATGGTCAGGC TGGGGTACAG CCTGCTCTCG GTGTGGGCCT ATGATCTAGG CTCTCGCCTC TTCCAGGAGA AGATACAAAT CCACAAGAAA CAAAGAGGAC ACGGCTGGTT TTCATTGTGA AAGATAGCTA CACCTCACAA GGAAATGGAC TGCCTCTCTT GAGCACTTCC CTGGAGCTAC CACGTATCTA GCTAATATGT ATGTGTCAGT AGTAGCACCA AGGATTGACA AATATATTTA TGATCTATTC AGCTGCTTTT ACTGTGTGGA TTATGCCAAC AGCTTGAATG GATTCTAACA GACTCTTTTG TTTTTAAAAG

TCTGCCTTGT TTATGGTGGA AAATTACTGA AACTATTTTA CTGTGAAACA GTGTGAACTA TTATAATGCA AATACTTTTT AACTTAGAGG CAATGGAAAA ATAAAAGTTG ACTGTACTAA AAATGTATAC TTGTTGCCAG GAAGGTGACC TCAAAAATTA AAAGTATAAT TATTCGGCCG GGCATGGTGG CTCACACCTG TAATTCCAGC ACTTTGGGAG GCCAAGGCAG GCGGATCACG AGGTCAGGAG TTCAAAACCA GCCTGTCCAA TATAGTG (FRAG NO _) ( SEQ ID NO 2424) 5'-GCGCGTCCTG-3' (FRAG NO 1671) (SEQ NO 11055) 5'-GCT GGG CCC CGG-3' (FRAG NO 1672) (SEQ D NO 11056)

5'-CGG GTC GGG GCC CCC C-3' (FRAG NO 1673) (SEQ ED NO 11057)

5'- CGC GCC CGC G-3' (FRAG NO 1674) (SEQ DD NO 11058)

5'-GGC GCC GTG CCG CGT CTT GGT GGC GGC GG-3' (FRAG 972) (SEQ DD NO 10351)

5'-GTT CGC GCC CGC GCG GGG CCC CTC CGG TCC-3' (FRAG 973) (SEQ DD NO 10352) 5'-GTT CGC GCC CGC GCG GGG CCC CTC CGG TCC-3' (FRAG 974) (SEQ DD NO 10353)

5'-CGG GTC GGG GCC CCC CGC GGC C-3' (FRAG975) (SEQ ID NO 10354) 5'-GCC TCG GGG CTG GGG CGC TGG TGG CCG GG-3' (FRAG 976) (SEQ DD NO 10355) 5'-CCG CGC CTC CGC CTG CCG CTT CTG-3' (FRAG 977) (SEQ DD NO 10356) 5'-GCT GGG CCC CGG GCG CCC CCT-3' (FRAG 978) (SEQ ID NO 10357) 5'-CCC CTC TTG CTC GGG TCC CCG TG-3' (FRAG 979) (SEQ ID NO 10358)

5'-ACAGCGCGTCCTGTGTCTCCAGCAGCATGGCCGGGCCAGCTGGGCCCC-3' (FRAG 980) (SEQ DD NO 10359) 5'-BCBGCGCGTCCTGTGTCTCCBGCBGCBTGGCCGGGCCBGCTGGGCCCC-3' (FRAG 981) (SEQ DD O 10360)

Human Adenosine A^ Receptor Nucleic Acid and Antisense Oligonucleotide Fragments

5'-ACA GAG CAG TGC TGT TGT TGG GCA TCT TGC CTT CCC AGG G BCB GBG CB TGC TGT TGT TGG GCB TCT TGC CTT CCC BGG GCC CTT TTC TGG TGG GGT GGT GCT GTT GTT GGG CTT TCT TCT GTT CCC BCB GBG CBG TGC TGT TGT TGG GCB TCT TGC CTT CCC BGG GCC CTT TTC TGG TGG GGT GGT GCT GTT GTT GGG C TTT

CTT CTG TTC CC GAATTCCCAG ATGGGCAGAG GTGGCTGGGC TGGTGACCCT AAGTGTGTCT CCTGCCTTTA TTCTCTCTAG TGGGTTATTC TTTCATGTGG TATCTTGCCT ACAGCATGCT GTGTTTGGAC ACAAACCCCT TTCCTTGGTT TCTCTGACCC AGCTGAGATG GACTGATTCC AAAAGAACTC ACCTATGTAC TGGGGTAGGG GAGGGAGGGT TTTTTGCAGT ATTTAACTAA GGTTCAAAGA GTGCTATATA GTGAGAAAGG CTTCTTTTTT χ_Tχχχχχχχ_T χχχιTTGGCA GAGTGCTGCC TCCTAGAAAT TTCTCTTGGT AACTTCCTTC TCTGAAGCAC AGATAAAGAA AACAATTACA GTAGAAACAT TTATGAGGGA CACATTGGAG GCCGATGAAG CTTTTCAAGT TCCAGCAGTG CAGGGATGTG GGCAGAACTG ACATTGGAAA ATACTAGAAT GATGGAAATT CAGTTGGAGA GGACTGCCCT TTTTAATGTC TGGGGAGTCT GCTCAGGGAG AAATGACAAG

TCTGGCGGGG ACAAGTATGG GATTTGGTAA GACTTGGATC AACTTGGGAT ACAGGGTGGG GGTCGGGAGT GGAATCAATG AATGATGCCA GAGCAGATCA ACTAACAAGA GGACCCTGAT GAGCCCCAGG CAGAGGCGTC TCCCTTATGC CCCACTCTGA AGTGTTTGTT AGTAAACACC AGAACGCCAT TGTTGTTACT GCTGAATTTT ATTTTGGGCT GTACATATTT AGATGCTTAA GGTAAAAATG ATAAAGCCCT CAAGCCACTG TGTGGGTTTG GGTCCAAGTG TTCCTTCTTG CTGCCTCTCT AACACGCCTG GTTAAAATAA TCCCTTTGGA TGGTGCTGAG AAGCACCTGA ACCAAGTGGG TCCCCAAATA ACAATGGCGT GCAAGTGTCT GGTTCCCAGA AGTTGGTGAC TAGGTAAGCA GCTTCAGGGA GAGGGGGCTG ATTCCCAGAC AGTCGCCTGT TCCTGCGGGG ATGGGGCTGA GGCTTGGGGA ATGTGGGCAG GAGGATATGC CATTTGATTC TGTTGCACAC

GTTCTTTTCC CTTCTTTCTG TATGTCTGGT CATTCTGCTA TTCTGTCGTT CCTCACATAG GTTGGACATT GGCCGGCTGC CAGCATAAGT GCCAGTGTGA TTTTGCTAGG TGTGAGCTGA GAAAGAGAGG TGGAGGCTAA GCAGGTGTGA TGCTTCTCAG AGGTGCTGAG TTTTTGCCCT TCTGAGCAGG GAATCTTTGC TTATCCCTTT GACCAAGGAT CTTTGCTGCA AAGGCTGGGT ATCGGCTGTG CTCAGCAAAG CGTCAACTCG TGCAAGAACT TAGCAGGAAT AGTTCTGGCT AAGGTTAGGA GGCTGCCACC AAAGTCTCTT TTTTGTTCCT CTGCTTCTCC CGTTTGCCTC CTTATCATGA GATCTTTTTG CTAAGCTGGC AGAAAGATTG CATAGTCAGT GCTTCCAGCT CTGCTCCCAC CTGATCCTGC ACTGTCCTCT GGTCCCTGAA TGAATGAACT CTGATACCCA ATCTTGTCTC GAGCCTTCTC TATGCCACTC ATGGCTCCTC TTCTGCTCTT TCCATCTTTT TGCTGAGAGT

TCTGAGCTCT GTACTTCCTC TTGGCCCATC TCACTTCCTG AAACACCCCT GAAGAGGGTT GCTTATCTTG ATGGAACTCA AAAAGCCAAA AAGCTGCAGG CAGAGGCGTT GAGGACATCT GTTTGGGGAA CTAAGAGCAG CAGCACTTTC AGATTCAGTC CATATAGAGC TGTCCTACAG CATTCTGGAA ACTTGAGGAT GTGCGGTGCA TAAAGGGGCT GGAAGTGACC CACCTGTGAT GAGCCCTTTC TAAGGAGAAG GGTTTCCAAG AGATCACCCC ACCAGAAAAG OGTAGGAATG AGCAAGTTGG GAATTTTAGA CTGTCACTGC ACATGGACCT CTGGGAAGAC GTCTGGCGAG AGCTAGGCCC ACTGGCCCTA CAGACGGATC TTGCTGGCTC ACCTGTCCCT GTGGAGGTTC CCCTGGGAAG GCAAGATGCC CAACAACAGC ACTGCTCTGT CATTGGCCAA TGTTACCTAC ATCACCATGG AAATTTTCAT TGGACTCTGC GCCATAGTGG GCAACGTGCT GGTCATCTGC GTGGTCAAGC

TGAACCCCAG CCTGCAGACC ACCACCTTCT ATTTCATTGT CTCTCTAGCC CTGGCTGACA TTGCTGTTGG GGTGCTGGTC ATGCCTTTGG CCATTGTTGT CAGCCTGGGC ATCACAATCC ACTTCTACAG CTGCCTTTTT ATGACTTGCC TACTGCTTAT CTTTACCCAC GCCTCCATCA TGTCCTTGCT GGCCATCGCT GTGGACCGAT ACTTGCGGGT CAAGCTTACC GTCAGGTAGC CTGCGGCGTG GGGTGGGCAG CAATTGAGGC AGCTGGGAAA TGAGGCTACA AAGCCAGAGC CTGCTGAATT TTATTTTGGA CTGTACATAT TTAGATGCTT AAGGTAAAAA TGATAAAGCC CTCAAGCCAC TGTGTGGGTT GGGTCCAAGT GTTCCTTGCT GCTGCCTCTC TAACACGCCT GGTTAAAATA ATCCCTTTGG ATGGTGCTGA GAAGCACCTG AACCAAGTGG GTCCCCAAAT AACTATGGCG TGCAAGTGTC TGGTTCCCAG AAGTTGGTGA CTAGGTAAGC GACTCAGGGA

GAGGGGCTGA TTCCCAGACA GTCGCCTGTT CCTGCTGGGA TGGGGCTGAG GCTTGGGGAA TGTGGGCAGG AGGATATGCC ATTTGATTCT GTTGCACACG TTCTTTTCCC TTCTTTCTGT ATGTCTGGTC ATTCTGCTAT TCTGTCGTTC CTCACATAGG TTGGACATTG GCCGGCTGCC AGCATAAGTG CCAGTGTGAT TTTGCTAGGG TGTGAGCTGA GAAAGAGAGG TGGAGGCTAA GCAGGTGTGA TGCTTCTCAG AGGTGCTGAG TTTTTGCCCT TCTGAGCAGG GAATCTTTGC TTATCCCTTT GACCAAGGAT CTTTGCTCCA AAGGCTGGGT ATCGGCTGTG CTCAGCAAAG CGTCAACTCG TGCAAGAACT TAGCAGGAAT AGTTCTGGCT AAGGTTAGGA GGCTGCCACC AAAGTCTCTT TTTTGTTCCT CTGCTTCTCC CGTTTGCCTC CTTATCATGA GATCTTTTTG CTAAGCTGGC AGAAAGATTG CATAATCAGT GCTTCCAGCT CCGCTCCCAC CTGATCCTGC ACTGTCCTCT

GGTCCCTGAA TGAATGAACT CTGATACCCA ATCTTGTCTC GAGCCTTCTC TATGCCACTC ATGGCTCCTC TTCTGCTCTT TCCATCTTTT TGCTGAGAGT TACTGAGCTC TGTACTTCCT CTTGGCCCAT CTCACTTCCT GAAACACCCC TGAAGAGGGT TGCTTATCTT GATGGAACTC AAAAAGCCAA AAAGCTGCAG GCAGAGGCGT TGAGGACATC TGTTTGGGGA ACTAAGAGCA GCAGCACTTT CAGATTCAGT CCATATAGAG CTGTCCTACA GCATTCTGGA AACTTGAGGA TGTGCGGTGC ATAAAGGGOC TGGAAGTGAC CCACCTGTGA TGAGCCCTTT CTAAGGAGAA GGGTTTCCAA GAGATCACCC CACCAGAAAA GGGTAGGAAT GAGCAAGTTG GGAATTTTAG ACTGTCACTG CACATGGACC TCTGGGAAGA CGTCTGGCGA GAGCTAGGCC CACTGGCCCT ACAGACGGAT CTTGCTGGCT CACCTGTCCC TGTGGAGGTT CCCCTGGGAA GGCAAGATGC CCAACAACAG

CACTGCTCTG CGAATTCGGG GGACATCTGT TTGGGGAACT AAGAGCAGCA GCACTTTCAG ATTCAGTCCA TATAGAGCTG TCCTACAGCA TTCTGGAAAC TTGAGGATGT GCGGTGCATA AACGGGCTGG AAGTGACCCA CCTGTGATGA GCCCTTTCTA AGGAGAAGGG TTTCCAAGAG ATCACCCCAC CAGAAAAGGG TAGGAATGAG CAAGTTGGGA ATTTTAGACT GTCACTGCAC ATGGACCTCT GGGAAGACGT CTGGCGAGAG CTAGGCCCAC TGGCCCTACA GACGGATCTT GCTGGCTCAC CTGTCCCTGT GGAGGTTCCC CTGGGAAGGC AAGATGCCCA ACAACAGCAC TGCTCTGTCA TTGGCCAATG TTACCTACAT CACCATGGAA ATTTTCATTG GACTCTGCGC CATAGTGGGC AACGTGCTGG TCATCTGCGT GGTCAAGCTG AACCCCAGCC TGCAGACCAC CACCTTCTAT TTCATTGTCT CTCTAGCCCT GGCTGACATT GCTGTTGGGG TGCTGGTCAT

GCCTTTGGCC ATTGTTGTCA GCCTGGGCAT CACAATCCAC TTCTACAGCT GCCTTTTTAT GACTTGCCTA CTGCTTATCT TTACCCACGC CTCCATCATG TCCTTGCTGG CCATCGCTGT GGACCGATAC TTGCGGGTCA AGCTTACCGT CAGATACAAG AGGGTCACCA CTCACAGAAG AATATGGCTG GCCCTGGGCC TTTGCTGGCT GGTGTCATTC CTGGTGGGAT TGACCCCCAT GTTTGGCTGG AACATGAAAC TGACCTCAGA GTACCACAGA AATGTCACCT TCCTTTCATG CCAATTTGTT TCCGTCATGA GGATGGACTA CATGGTATAC TTCAGCTTCC TCACCTGGAT TTTCATCCCC CTGGTTGTCA TGTGCGCCAT CTATCTTGAC ATCTTTTACA TCATTCGGAA CAAACTCAGT CTGAACTTAT CTAACTCCAA AGAGACAGGT GCATTTTATG GACGGGAGTT CAAGACGGCT AAGTCCTTGT TTCTGGTTCT TTTCTTGTTT GCTCTGTCAT GGCTGCCTTT ATCTCTCATC AACTGCATCA TCTACTTTAA TGGTGAGGTA CCACAGCTTG TGCTGTACAT GGGCATCCTG CTGTCCCATG CCAACTCCAT GATGAACCCT ATCGTCTATG CCTATAAAAT AAAGAAGTTC AAGGAAACCT ACCTTTTGAT CCTCAAAGCC TGTGTGGTCT GCCATCCCTC TGATTCTTTG GACACAAGCA TTGAGAAGAA TTCTGAGTAG TTATCCATCA GAGATGACTC TGTCTCATTG ACCTTCAGAT TCCCCATCAA CAAACACTTG AGGGCCTGTA TGCCTGGGCC AAGGGATTTT TACATCCTTG ATTACTTCCA CTGAGGTGGG AGCATCTCCA GTGCTCCCCA ATTATATCTC CCCCACTCCA CTACTCTCTT CCTCCACTTC ATTTTTCCTT TGTCCTTTCT CTCTAATTCA GTGTTTTGGA GGCCTGACTT

GGGGACAACG TATTATTGAT ATTATTGTCT GTTTTCCTTC TTCCCAATAG AAGAATAAGT CATGGAGCCT GAAGGGTGCC TAGTTGACTT ACTGACAAAA GGCTCTAGTT GGGCTGAACA TGTGTGTGGT GGTGACTCAT TTCCATGCCA TTGTGGAATT GAGCAGAGAA CCTGCTCTCG GAGGATGCCT AGGAGATGTT GGGAACAGAA GAAATAAACT GAGTTTAAGG GGGACTTAAA CTGCTGAATT C GAATTCCCAG ATGGGCAGAG GTGGCTGGGC TGGTGACCCT AAGTGTGTCT CCTGCCTTTA TTCTCTCTAG TGGGTTATTC TTTCATGTGG TATCTTGCCT ACAGCATGCT GTGTTTGGAC ACAAACCCCT TTCCTTGGTT TCTCTGACCC AGCTGAGATG GACTGATTCC AAAAGAACTC ACCTATGTAC TGGGGTAGGG GAGGGAGGGT TTTTTGCAGT ATTTAACTAA GGTTCAAAGA GTGCTATATA GTGAGAAAGG CTTCTTTTTT TTTTTTTTTT TTTTTTGGCA GAGTGCTGCC

TCCTAGAAAT TTCTCTTGGT AACTTCCTTC TCTGAAGCAC AGATAAAGAA AACAATTACA GTAGAAACAT TTATGAGGGA CACATTGGAG GCCGATGAAG CTTTTCAAGT TCCAGCAGTG CAGGGATGTG GGCAGAACTG ACATTGGAAA ATACTAGAAT GATGGAAATT CAGTTGGAGA GGACTGCCCT TTTTAATGTC TGGGGAGTCT GCTCAGGGAG AAATGACAAG TCTGGCGGGG ACAAGTATGG GATTTGGTAA GACTTGGATC AACTTGGGAT ACAGGGTGGG GGTCGGGAGT GGAATCAATG AATGATGCCA GAGCAGATCA ACTAACAAGA GGACCCTGAT GAGCCCCAGG CAGAGGCGTC TCCCTTATGC CCCACTCTGA AGTGTTTGTT AGTAAACACC AGAACGCCAT TGTTGTTACT GCTGAATTTT ATTTTGGGCT GTACATATTT AGATGCTTAA GGTAAAAATG ATAAAGCCCT CAAGCCACTG TGTGGGTTTG GGTCCAAGTG TTCCTTCTTG CTGCCTCTCT

AACACGCCTG GTTAAAATAA TCCCTTTGGA TGGTGCTGAG AAGCACCTGA ACCAAGTGGG TCCCCAAATA ACAATGGCGT GCAAGTGTCT GGTTCCCAGA AGTTGGTGAC TAGGTAAGCA GCTTCAGGGA GAGGGGGCTG ATTCCCAGAC AGTCGCCTGT TCCTGCGGGG ATGGGGCTGA GGCTTGGGGA ATGTGGGCAG GAGGATATGC CATTTGATTC TGTTGCACAC GTTCTTTTCC CTTCTTTCTG TATGTCTGGT CATTCTGCTA TTCTGTCGTT CCTCACATAG GTTGGACATT GGCCGGCTGC CAGCATAAGT GCCAGTGTGA TTTTGCTAGG TGTGAGCTGA GAAAGAGAGG TGGAGGCTAA GCAGGTGTGA TGCTTCTCAG AGGTGCTGAG TTTTTGCCCT TCTGAGCAGG GAATCTTTGC TTATCCCTTT GACCAAGGAT CTTTGCTGCA AAGGCTGGGT ATCGGCTGTG CTCAGCAAAG CGTCAACTCG TGCAAGAACT TAGCAGGAAT AGTTCTGGCT AAGGTTAGGA

GGCTGCCACC AAAGTCTCTT TTTTGTTCCT CTGCTTCTCC CGTTTGCCTC CTTATCATGA GATCTTTTTG CTAAGCTGGC AGAAAGATTG CATAGTCAGT GCTTCCAGCT CTGCTCCCAC CTGATCCTGC ACTGTCCTCT GGTCCCTGAA TGAATGAACT CTGATACCCA ATCTTGTCTC GAGCCTTCTC TATGCCACTC ATGGCTCCTC TTCTGCTCTT TCCATCTTTT TGCTGAGAGT TCTGAGCTCT GTACTTCCTC TTGGCCCATC TCACTTCCTG AAACACCCCT GAAGAGGGTT GCTTATCTTG ATGGAACTCA AAAAGCCAAA AAGCTGCAGG CAGAGGCGTT GAGGACATCT GTTTGGGGAA CTAAGAGCAG CAGCACTTTC AGATTCAGTC CATATAGAGC TGTCCTACAG CATTCTGGAA ACTTGAGGAT GTGCGGTGCA TAAAGGGGCT GGAAGTGACC CACCTGTGAT GAGCCCTTTC TAAGGAGAAG GGTTTCCAAG AGATCACCCC ACCAGAAAAG GGTAGGAATG

AGCAAGTTGG GAATTTTAGA CTGTCACTGC ACATGGACCT CTGGGAAGAC GTCTGGCGAG AGCTAGGCCC ACTGGCCCTA CAGACGGATC TTGCTGGCTC ACCTGTCCCT GTGGAGGTTC CCCTGGGAAG GCAAGATGCC CAACAACAGC ACTGCTCTGT CATTGGCCAA TGTTACCTAC ATCACCATGG AAATTTTCAT TGGACTCTGC GCCATAGTGG GCAACGTGCT GGTCATCTGC GTGGTCAAGC TGAACCCCAG CCTGCAGACC ACCACCTTCT ATTTCATTGT CTCTCTAGCC CTGGCTGACA TTGCTGTTGG GGTGCTGGTC ATGCCTTTGG CCATTGTTGT CAGCCTGGGC ATCACAATCC ACTTCTACAG CTGCCTTTTT ATGACTTGCC TACTGCTTAT CTTTACCCAC GCCTCCATCA TGTCCTTGCT GGCCATCGCT GTGGACCGAT ACTTGCGGGT CAAGCTTACC GTCAGGTAGC CTGCGGCGTG GGGTGGGCAG CAATTGAGGC AGCTGGGAAA TGAGGCTACA

AAGCCAGAGC CTGCTGAATT TTATTTTGGA CTGTACATAT TTAGATGCTT AAGGTAAAAA TGATAAAGCC CTCAAGCCAC TGTGTGGGTT GGGTCCAAGT GTTCCTTGCT GCTGCCTCTC TAACACGCCT GGTTAAAATA ATCCCTTTGG ATGGTGCTGA GAAGCACCTG AACCAAGTGG GTCCCCAAAT AACTATGGCG TGCAAGTGTC TGGTTCCCAG AAGTTGGTGA CTAGGTAAGC GACTCAGGGA GAGGGGCTGA TTCCCAGACA GTCGCCTGTT CCTGCTGGGA TGGGGCTGAG GCTTGGGGAA TGTGGGCAGG AGGATATGCC ATTTGATTCT GTTGCACACG TTCTTTTCCC TTCTTTCTGT ATGTCTGGTC ATTCTGCTAT TCTGTCGTTC CTCACATAGG TTGGACATTG GCCGGCTGCC AGCATAAGTG CCAGTGTGAT TTTGCTAGGG TGTGAGCTGA GAAAGAGAGG TGGAGGCTAA GCAGGTGTGA TGCTTCTCAG AGGTGCTGAG TTTTTGCCCT TCTGAGCAGG

GAATCTTTGC TTATCCCTTT GACCAAGGAT CTTTGCTCCA AAGGCTGGGT ATCGGCTGTG CTCAGCAAAG CGTCAACTCG TGCAAGAACT TAGCAGGAAT AGTTCTGGCT AAGGTTAGGA GGCTGCCACC AAAGTCTCTT TTTTGTTCCT CTGCTTCTCC CGTTTGCCTC CTTATCATGA GATCTTTTTG CTAAGCTGGC AGAAAGATTG CATAATCAGT GCTTCCAGCT CCGCTCCCAC CTGATCCTGC ACTGTCCTCT GGTCCCTGAA TGAATGAACT CTGATACCCA ATCTTGTCTC GAGCCTTCTC TATGCCACTC ATGGCTCCTC TTCTGCTCTT TCCATCTTTT TGCTGAGAGT TACTGAGCTC TGTACTTCCT CTTGGCCCAT CTCACTTCCT GAAACACCCC TGAAGAGGGT TGCTTATCTT GATGGAACTC AAAAAGCCAA AAAGCTGCAG GCAGAGGCGT TGAGGACATC TGTTTGGGGA ACTAAGAGCA GCAGCACTTT CAGATTCAGT CCATATAGAG CTGTCCTACA GCATTCTGGA

AACTTGAGGA TGTGCGGTGC ATAAAGGGGC TGGAAGTGAC CCACCTGTGA TGAGCCCTTT CTAAGGAGAA GGGTTTCCAA GAGATCACCC CACCAGAAAA GGGTAGGAAT GAGCAAGTTG GGAATTTTAG ACTGTCACTG CACATGGACC TCTGGGAAGA CGTCTGGCGA GAGCTAGGCC CACTGGCCCT ACAGACGGAT CTTGCTGGCT CACCTGTCCC TGTGGAGGTT CCCCTGGGAA GGCAAGATGC CCAACAACAG CACTGCTCTG CGAATTCGGG GGACATCTGT TTGGGGAACT AAGAGCAGCA GCACTTTCAG ATTCAGTCCA TATAGAGCTG TCCTACAGCA TTCTGGAAAC TTGAGGATGT GCGGTGCATA AACGGGCTGG AAGTGACCCA CCTGTGATGA GCCCTTTCTA AGGAGAAGGG TTTCCAAGAG ATCACCCCAC CAGAAAAGGG TAGGAATGAG CAAGTTGGGA ATTTTAGACT GTCACTGCAC ATGGACCTCT GGGAAGACGT CTGGCGAGAG CTAGGCCCAC

TGGCCCTACA GACGGATCTT GCTGGCTCAC CTGTCCCTGT GGAGGTTCCC CTGGGAAGGC AAGATGCCCA ACAACAGCAC TGCTCTGTCA TTGGCCAATG TTACCTACAT CACCATGGAA ATTTTCATTG GACTCTGCGC CATAGTGGGC AACGTGCTGG TCATCTGCGT GGTCAAGCTG AACCCCAGCC TGCAGACCAC CACCTTCTAT TTCATTGTCT CTCTAGCCCT GGCTGACATT GCTGTTGGGG TGCTGGTCAT GCCTTTGGCC ATTGTTGTCA GCCTGGGCAT CACAATCCAC TTCTACAGCT GCCTTTTTAT GACTTGCCTA CTGCTTATCT TTACCCACGC CTCCATCATG TCCTTGCTGG CCATCGCTGT GGACCGATAC TTGCGGGTCA AGCTTACCGT CAGATACAAG AGGGTCACCA CTCACAGAAG AATATGGCTG GCCCTGGGCC TTTGCTGGCT GGTGTCATTC CTGGTGGGAT TGACCCCCAT GTTTGGCTGG AACATGAAAC TGACCTCAGA GTACCACAGA AATGTCACCT

TCCTTTCATG CCAATTTGTT TCCGTCATGA GGATGGACTA CATGGTATAC TTCAGCTTCC TCACCTGGAT TTTCATCCCC CTGGTTGTCA TGTGCGCCAT CTATCTTGAC ATCTTTTACA TCATTCGGAA CAAACTCAGT CTGAACTTAT CTAACTCCAA AGAGACAGGT GCATTTTATG GACGGGAGTT CAAGACGGCT AAGTCCTTGT TTCTGGTTCT

TTTCTTGTTT GCTCTGTCAT GGCTGCCTTT ATCTCTCATC AACTGCATCA TCTACTTTAA TGGTGAGGTA CCACAGCTTG TGCTGTACAT GGGCATCCTG CTGTCCCATG

CCAACTCCAT GATGAACCCT ATCGTCTATG CCTATAAAAT AAAGAAGTTC AAGGAAACCT ACCTTTTGAT CCTCAAAGCC TGTGTGGTCT GCCATCCCTC TGATTCTTTG GACACAAGCA TTGAGAAGAA TTCTGAGTAG TTATCCATCA GAGATGACTC TGTCTCATTG ACCTTCAGAT TCCCCATCAA CAAACACTTG AGGGCCTGTA TGCCTGGGCC

AAGGGATTTT TACATCCTTG ATTACTTCCA CTGAGGTGGG AGCATCTCCA GTGCTCCCCA ATTATATCTC CCCCACTCCA CTACTCTCTT CCTCCACTTC ATTTTTCCTT TGTCCTTTCT CTCTAATTCA GTGTTTTGGA GGCCTGACTT GGGGACAACG TATTATTGAT ATTATTGTCT GTTTTCCTTC TTCCCAATAG AAGAATAAGT CATGGAGCCT GAAGGGTGCC TAGTTGACTT ACTGACAAAA GGCTCTAGTT GGGCTGAACA TGTGTGTGGT GGTGACTCAT TTCCATGCCA TTGTGGAATT GAGCAGAGAA CCTGCTCTCG GAGGATGCCT AGGAGATGTT GGGAACAGAA GAAATAAACT GAGTTTAAGG GGGACTTAAA CTGCTGAATT C -3' (FRAG NO 1675) (SEQ DD NO 12376) 5'- CGAATTCGGG GGACATCTGT TTGGGGAACT AAGAGCAGCA GCACTTTCAG ATTCAGTCCA TATAGAGCTG TCCTACAGCA TTCTGGAAAC TTGAGGATGT

GCGGTGCATA AACGGGCTGG AAGTGACCCA CCTGTGATGA GCCCTTTCTA AGGAGAAGGG TTTCCAAGAG ATCACCCCAC CAGAAAAGGG TAGGAATGAG CAAGTTGGGA ATTTTAGACT GTCACTGCAC ATGGACCTCT GGGAAGACGT CTGGCGAGAG CTAGGCCCAC TGGCCCTACA GACGGATCTT GCTGGCTCAC CTGTCCCTGT GGAGGTTCCC CTGGGAAGGC AAGATGCCCA ACAACAGCAC TGCTCTGTCA TTGGCCAATG TTACCTACAT CACCATGGAA ATTTTCATTG GACTCTGCGC CATAGTGGGC AACGTGCTGG TCATCTGCGT GGTCAAGCTG AACCCCAGCC TGCAGACCAC CACCTTCTAT TTCATTGTCT CTCTAGCCCT GGCTGACATT GCTGTTGGGG TGCTGGTCAT GCCTTTGGCC ATTGTTGTCA GCCTGGGCAT CACAATCCAC TTCTACAGCT GCCTTTTTAT GACTTGCCTA CTGCTTATCT TTACCCACGC CTCCATCATG TCCTTGCTGG

CCATCGCTGT GGACCGATAC TTGCGGGTCA AGCTTACCGT CAGATACAAG AGGGTCACCA CTCACAGAAG AATATGGCTG GCCCTGGGCC TTTGCTGGCT GGTGTCATTC CTGGTGGGAT TGACCCCCAT GTTTGGCTGG AACATGAAAC TGACCTCAGA GTACCACAGA AATGTCACCT TCCTTTCATG CCAATTTGTT TCCGTCATGA GGATGGACTA CATGGTATAC TTCAGCTTCC TCACCTGGAT TTTCATCCCC CTGGTTGTCA TGTGCGCCAT CTATCTTGAC ATCTTTTACA TCATTCGGAA CAAACTCAGT CTGAACTTAT CTAACTCCAA AGAGACAGGT GCATTTTATG GACGGGAGTT CAAGACGGCT AAGTCCTTGT TTCTGGTTCT TTTCTTGTTT GCTCTGTCAT GGCTGCCTTT ATCTCTCATC AACTGCATCA TCTACTTTAA TGGTGAGGTA CCACAGCTTG TGCTGTACAT GGGCATCCTG CTGTCCCATG CCAACTCCAT GATGAACCCT ATCGTCTATG CCTATAAAAT

AAAGAAGTTC AAGGAAACCT ACCTTTTGAT CCTCAAAGCC TGTGTGGTCT GCCATCCCTC TGATTCTTTG GACACAAGCA TTGAGAAGAA TTCTGAGTAG TTATCCATCA GAGATGACTC TGTCTCATTG ACCTTCAGAT TCCCCATCAA CAAACACTTG AGGGCCTGTA TGCCTGGGCC AAGGGATTTT TACATCCTTG ATTACTTCCA CTGAGGTGGG AGCATCTCCA GTGCTCCCCA ATTATATCTC CCCCACTCCA CTACTCTCTT CCTCCACTTC ATTTTTCCTT TGTCCTTTCT CTCTAATTCA GTGTTTTGGA GGCCTGACTT GGGGACAACG TATTATTGAT ATTATTGTCT GTTTTCCTTC TTCCCAATAG AAGAATAAGT CATGGAGCCT GAAGGGTGCC TAGTTGACTT ACTGACAAAA GGCTCTAGTT GGGCTGAACA TGTGTGTGGT GGTGACTCAT TTCCATGCCA TTGTGGAATT GAGCAGAGAA CCTGCTCTCG GAGGATGCCT AGGAGATGTT GGGAACAGAA GAAATAAACT

GAGTTTAAGG GGGACTTAAA CTGCTGAATT C -3' (FRAG NO J (SEQ ED NO 11808)

5'- CTGCTGAATT TTATTTTGGA CTGTACATAT TTAGATGCTT AAGGTAAAAA TGATAAAGCC CTCAAGCCAC TGTGTGGGTT GGGTCCAAGT GTTCCTTGCT GCTGCCTCTC TAACACGCCT GGTTAAAATA ATCCCTTTGG ATGGTGCTGA GAAGCACCTG AACCAAGTGG GTCCCCAAAT AACTATGGCG TGCAAGTGTC TGGTTCCCAG AAGTTGGTGA CTAGGTAAGC GACTCAGGGA GAGGGGCTGA TTCCCAGACA GTCGCCTGTT CCTGCTGGGA TGGGGCTGAG GCTTGGGGAA TGTGGGCAGG AGGATATGCC ATTTGATTCT GTTGCACACG TTCTTTTCCC TTCTTTCTGT ATGTCTGGTC ATTCTGCTAT TCTGTCGTTC CTCACATAGG TTGGACATTG GCCGGCTGCC AGCATAAGTG CCAGTGTGAT

TTTGCTAGGG TGTGAGCTGA GAAAGAGAGG TGGAGGCTAA GCAGGTGTGA TGCTTCTCAG AGGTGCTGAG TTTTTGCCCT TCTGAGCAGG GAATCTTTGC TTATCCCTTT GACCAAGGAT CTTTGCTCCA AAGGCTGGGT ATCGGCTGTG CTCAGCAAAG CGTCAACTCG TGCAAGAACT TAGCAGGAAT AGTTCTGGCT AAGGTTAGGA GGCTGCCACC AAAGTCTCTT TTTTGTTCCT CTGCTTCTCC CGTTTGCCTC CTTATCATGA GATCTTTTTG CTAAGCTGGC AGAAAGATTG CATAATCAGT GCTTCCAGCT CCGCTCCCAC CTGATCCTGC ACTGTCCTCT GGTCCCTGAA TGAATGAACT CTGATACCCA ATCTTGTCTC GAGCCTTCTC TATGCCACTC ATGGCTCCTC TTCTGCTCTT TCCATCTTTT TGCTGAGAGT TACTGAGCTC TGTACTTCCT CTTGGCCCAT CTCACTTCCT GAAACACCCC TGAAGAGGGT TGCTTATCTT GATGGAACTC AAAAAGCCAA AAAGCTGCAG

GCAGAGGCGT TGAGGACATC TGTTTGGGGA ACTAAGAGCA GCAGCACTTT CAGATTCAGT CCATATAGAG CTGTCCTACA GCATTCTGGA AACTTGAGGA TGTGCGGTGC ATAAAGGGGC TGGAAGTGAC CCACCTGTGA TGAGCCCTTT CTAAGGAGAA GGGTTTCCAA GAGATCACCC CACCAGAAAA GGGTAGGAAT GAGCAAGTTG GGAATTTTAG ACTGTCACTG CACATGGACC TCTGGGAAGA CGTCTGGCGA GAGCTAGGCC CACTGGCCCT ACAGACGGAT CTTGCTGGCT CACCTGTCCC TGTGGAGGTT CCCCTGGGAA GGCAAGATGC CCAACAACAG CACTGCTCTG -3' (FRAG NO (SEQ DD NO 11807) 5'- GAATTCCCAG ATGGGCAGAG GTGGCTGGGC TGGTGACCCT AAGTGTGTCT CCTGCCTTTA TTCTCTCTAG TGGGTTATTC TTTCATGTGG TATCTTGCCT ACAGCATGCT

GTGTTTGGAC ACAAACCCCT TTCCTTGGTT TCTCTGACCC AGCTGAGATG GACTGATTCC AAAAGAACTC ACCTATGTAC TGGGGTAGGG GAGGGAGGGT TTTTTGCAGT ATTTAACTAA GGTTCAAAGA GTGCTATATA GTGAGAAAGG CTTCTTTTTT χχχχ_Tτχ_Tχ_T χχτιχχGGCA GAGTGCTGCC TCCTAGAAAT TTCTCTTGGT AACTTCCTTC TCTGAAGCAC AGATAAAGAA AACAATTACA GTAGAAACAT TTATGAGGGA CACATTGGAG GCCGATGAAG CTTTTCAAGT TCCAGCAGTG CAGGGATGTG GGCAGAACTG ACATTGGAAA ATACTAGAAT GATGGAAATT CAGTTGGAGA GGACTGCCCT TTTTAATGTC TGGGGAGTCT GCTCAGGGAG AAATGACAAG TCTGGCGGGG ACAAGTATGG GATTTGGTAA GACTTGGATC AACTTGGGAT ACAGGGTGGG GGTCGGGAGT GGAATCAATG AATGATGCCA GAGCAGATCA ACTAACAAGA GGACCCTGAT

GAGCCCCAGG CAGAGGCGTC TCCCTTATGC CCCACTCTGA AGTGTTTGTT AGTAAACACC AGAACGCCAT TGTTGTTACT GCTGAATTTT ATTTTGGGCT GTACATATTT AGATGCTTAA GGTAAAAATG ATAAAGCCCT CAAGCCACTG TGTGGGTTTG GGTCCAAGTG TTCCTTCTTG CTGCCTCTCT AACACGCCTG GTTAAAATAA TCCCTTTGGA TGGTGCTGAG AAGCACCTGA ACCAAGTGGG TCCCCAAATA ACAATGGCGT GCAAGTGTCT GGTTCCCAGA AGTTGGTGAC TAGGTAAGCA GCTTCAGGGA GAGGGGGCTG ATTCCCAGAC AGTCGCCTGT TCCTGCGGGG ATGGGGCTGA GGCTTGGGGA ATGTGGGCAG GAGGATATGC CATTTGATTC TGTTGCACAC GTTCTTTTCC CTTCTTTCTG TATGTCTGGT CATTCTGCTA TTCTGTCGTT CCTCACATAG GTTGGACATT GGCCGGCTGC CAGCATAAGT GCCAGTGTGA TTTTGCTAGG TGTGAGCTGA GAAAGAGAGG TGGAGGCTAA GCAGGTGTGA TGCTTCTCAG AGGTGCTGAG TTTTTGCCCT TCTGAGCAGG GAATCTTTGC TTATCCCTTT GACCAAGGAT CTTTGCTGCA AAGGCTGGGT ATCGGCTGTG CTCAGCAAAG CGTCAACTCG TGCAAGAACT TAGCAGGAAT AGTTCTGGCT AAGGTTAGGA GGCTGCCACC AAAGTCTCTT TTTTGTTCCT CTGCTTCTCC CGTTTGCCTC CTTATCATGA GATCTTTTTG CTAAGCTGGC AGAAAGATTG CATAGTCAGT GCTTCCAGCT CTGCTCCCAC CTGATCCTGC ACTGTCCTCT GGTCCCTGAA TGAATGAACT CTGATACCCA ATCTTGTCTC GAGCCTTCTC TATGCCACTC ATGGCTCCTC TTCTGCTCTT TCCATCTTTT TGCTGAGAGT TCTGAGCTCT

GTACTTCCTC TTGGCCCATC TCACTTCCTG AAACACCCCT GAAGAGGGTT GCTTATCTTG ATGGAACTCA AAAAGCCAAA AAGCTGCAGG CAGAGGCGTT GAGGACATCT GTTTGGGGAA CTAAGAGCAG CAGCACTTTC AGATTCAGTC CATATAGAGC TGTCCTACAG CATTCTGGAA ACTTGAGGAT GTGCGGTGCA TAAAGGGGCT GGAAGTGACC CACCTGTGAT GAGCCCTTTC TAAGGAGAAG GGTTTCCAAG AGATCACCCC ACCAGAAAAG GGTAGGAATG AGCAAGTTGG GAATTTTAGA CTGTCACTGC ACATGGACCT CTGGGAAGAC GTCTGGCGAG AGCTAGGCCC ACTGGCCCTA CAGACGGATC TTGCTGGCTC ACCTGTCCCT GTGGAGGTTC CCCTGGGAAG GCAAGATGCC CAACAACAGC ACTGCTCTGT CATTGGCCAA TGTTACCTAC ATCACCATGG AAATTTTCAT TGGACTCTGC GCCATAGTGG GCAACGTGCT GGTCATCTGC GTGGTCAAGC TGAACCCCAG

CCTGCAGACC ACCACCTTCT ATTTCATTGT CTCTCTAGCC CTGGCTGACA TTGCTGTTGG GGTGCTGGTC ATGCCTTTGG CCATTGTTGT CAGCCTGGGC ATCACAATCC ACTTCTACAG CTGCCTTTTT ATGACTTGCC TACTGCTTAT CTTTACCCAC GCCTCCATCA TGTCCTTGCT GGCCATCGCT GTGGACCGAT ACTTGCGGGT CAAGCTTACC GTCAGGTAGC CTGCGGCGTG GGGTGGGCAG CAATTGAGGC AGCTGGGAAA TGAGGCTACA AAGCCAGAGC -3' (FRAG NO J (SEQ ED NO 11S06) 5'-CGAATTCGGG GGACATCTGT TTGGGGAACT AAGAGCAGCA GCACTTTCAG ATTCAGTCCA TATAGAGCTG TCCTACAGCA TTCTGGAAAC TTGAGGATGT GCGGTGCATA AACGGGCTGG AAGTGACCCA CCTGTGATGA GCCCTTTCTA AGGAGAAGGG TTTCCAAGAG ATCACCCCAC CAGAAAAGGG TAGGAATGAG

CAAGTTGGGA ATTTTAGACT GTCACTGCAC ATGGACCTCT GGGAAGACGT CTGGCGAGAG CTAGGCCCAC TGGCCCTACA GACGGATCTT GCTGGCTCAC CTGTCCCTGT GGAGGTTCCC CTGGGAAGGC AAGATGCCCA ACAACAGCAC TGCTCTGTCA TTGGCCAATG TTACCTACAT CACCATGGAA ATTTTCATTG GACTCTGCGC CATAGTGGGC AACGTGCTGG TCATCTGCGT GGTCAAGCTG AACCCCAGCC TGCAGACCAC CACCTTCTAT TTCATTGTCT CTCTAGCCCT GGCTGACATT GCTGTTGGGG TGCTGGTCAT GCCTTTGGCC ATTGTTGTCA GCCTGGGCAT CACAATCCAC TTCTACAGCT GCCTTTTTAT GACTTGCCTA CTGCTTATCT TTACCCACGC CTCCATCATG TCCTTGCTGG CCATCGCTGT GGACCGATAC TTGCGGGTCA AGCTTACCGT CAGATACAAG AGGGTCACCA CTCACAGAAG AATATGGCTG GCCCTGGGCC TTTGCTGGCT GGTGTCATTC

CTGGTGGGAT TGACCCCCAT GTTTGGCTGG AACATGAAAC TGACCTCAGA GTACCACAGA AATGTCACCT TCCTTTCATG CCAATTTGTT TCCGTCATGA GGATGGACTA CATGGTATAC TTCAGCTTCC TCACCTGGAT TTTCATCCCC CTGGTTGTCA TGTGCGCCAT CTATCTTGAC ATCTTTTACA TCATTCGGAA CAAACTCAGT CTGAACTTAT CTAACTCCAA AGAGACAGGT GCATTTTATG GACGGGAGTT CAAGACGGCT AAGTCCTTGT TTCTGGTTCT TTTCTTGTTT GCTCTGTCAT GGCTGCCTTT ATCTCTCATC AACTGCATCA TCTACTTTAA TGGTGAGGTA CCACAGCTTG TGCTGTACAT GGGCATCCTG CTGTCCCATG CCAACTCCAT GATGAACCCT ATCGTCTATG CCTATAAAAT AAAGAAGTTC AAGGAAACCT ACCTTTTGAT CCTCAAAGCC TGTGTGGTCT GCCATCCCTC TGATTCTTTG GACACAAGCA TTGAGAAGAA TTCTGAGTAG TTATCCATCA

GAGATGACTC TGTCTCATTG ACCTTCAGAT TCCCCATCAA CAAACACTTG AGGGCCTGTA TGCCTGGGCC AAGGGATTTT TACATCCTTG ATTACTTCCA CTGAGGTGGG AGCATCTCCA GTGCTCCCCA ATTATATCTC CCCCACTCCA CTACTCTCTT CCTCCACTTC ATTTTTCCTT TGTCCTTTCT CTCTAATTCA GTGTTTTGGA GGCCTGACTT GGGGACAACG TATTATTGAT ATTATTGTCT GTTTTCCTTC TTCCCAATAG AAGAATAAGT CATGGAGCCT GAAGGGTGCC TAGTTGACTT ACTGACAAAA GGCTCTAGTT GGGCTGAACA TGTGTGTGGT GGTGACTCAT TTCCATGCCA TTGTGGAATT GAGCAGAGAA CCTGCTCTCG GAGGATGCCT AGGAGATGTT GGGAACAGAA GAAATAAACT GAGTTTAAGG GGGACTTAAA CTGCTGAATT C -3' (FRAG NO J (SEQ DD NO 11796)

5'-TTCCCAG ATGGGCAGAG GTGGCTGGGC TGGTGACCCT AAGTGTGTCT CCTGCCTTTA TTCTCTCTAG TGGGTTATTC TTTCATGTGG TATCTTGCCT ACAGCATGCT GTGTTTGGAC ACAAACCCCT TTCCTTGGTT TCTCTGACCC AGCTGAGATG GACTGATTCC AAAAGAACTC ACCTATGTAC TGGGGTAGGG GAGGGAGGGT TTTTTGCAGT ATTTAACTAA GGTTCAAAGA GTGCTATATA GTGAGAAAGG CTTCTTTTTT χ χχχχχ_τχχ xxxxxxGGCA GAGTGCTGCC TCCTAGAAAT TTCTCTTGGT AACTTCCTTC TCTGAAGCAC AGATAAAGAA AACAATTACA GTAGAAACAT TTATGAGGGA CACATTGGAG GCCGATGAAG CTTTTCAAGT TCCAGCAGTG CAGGGATGTG GGCAGAACTG ACATTGGAAA ATACTAGAAT GATGGAAATT CAGTTGGAGA GGACTGCCCT TTTTAATGTC TGGGGAGTCT GCTCAGGGAG AAATGACAAG TCTGGCGGGG ACAAGTATGG

GATTTGGTAA GACTTGGATC AACTTGGGAT ACAGGGTGGG GGTCGGGAGT GGAATCAATG AATGATGCCA GAGCAGATCA ACTAACAAGA GGACCCTGAT GAGCCCCAGG CAGAGGCGTC TCCCTTATGC CCCACTCTGA AGTGTTTGTT AGTAAACACC AGAACGCCAT TGTTGTTACT GCTGAATTTT ATTTTGGGCT GTACATATTT AGATGCTTAA GGTAAAAATG ATAAAGCCCT CAAGCCACTG TGTGGGTTTG GGTCCAAGTG TTCCTTCTTG CTGCCTCTCT AACACGCCTG GTTAAAATAA TCCCTTTGGA TGGTGCTGAG AAGCACCTGA ACCAAGTGGG TCCCCAAATA ACAATGGCGT GCAAGTGTCT GGTTCCCAGA AGTTGGTGAC TAGGTAAGCA GCTTCAGGGA GAGGGGGCTG ATTCCCAGAC AGTCGCCTGT TCCTGCGGGG ATGGGGCTGA GGCTTGGGGA ATGTGGGCAG GAGGATATGC CATTTGATTC TGTTGCACAC GTTCTTTTCC

CTTCTTTCTG TATGTCTGGT CATTCTGCTA TTCTGTCGTT CCTCACATAG GTTGGACATT GGCCGGCTGC CAGCATAAGT GCCAGTGTGA TTTTGCTAGG TGTGAGCTGA GAAAGAGAGG TGGAGGCTAA GCAGGTGTGA TGCTTCTCAG AGGTGCTGAG TTTTTGCCCT TCTGAGCAGG GAATCTTTGC TTATCCCTTT GACCAAGGAT CTTTGCTGCA AAGGCTGGGT ATCGGCTGTG CTCAGCAAAG CGTCAACTCG TGCAAGAACT TAGCAGGAAT AGTTCTGGCT AAGGTTAGGA GGCTGCCACC AAAGTCTCTT TTTTGTTCCT CTGCTTCTCC CGTTTGCCTC CTTATCATGA GATCTTTTTG CTAAGCTGGC AGAAAGATTG CATAGTCAGT GCTTCCAGCT CTGCTCCCAC CTGATCCTGC ACTGTCCTCT GGTCCCTGAA TGAATGAACT CTGATACCCA ATCTTGTCTC GAGCCTTCTC TATGCCACTC ATGGCTCCTC TTCTGCTCTT TCCATCTTTT TGCTGAGAGT TCTGAGCTCT

GTACTTCCTC TTGGCCCATC TCACTTCCTG AAACACCCCT GAAGAGGGTT GCTTATCTTG ATGGAACTCA AAAAGCCAAA AAGCTGCAGG CAGAGGCGTT GAGGACATCT GTTTGGGGAA CTAAGAGCAG CAGCACTTTC AGATTCAGTC CATATAGAGC TGTCCTACAG CATTCTGGAA ACTTGAGGAT GTGCGGTGCA TAAAGGGGCT GGAAGTGACC CACCTGTGAT GAGCCCTTTC TAAGGAGAAG GGTTTCCAAG AGATCACCCC ACCAGAAAAG GGTAGGAATG AGCAAGTTGG GAATTTTAGA CTGTCACTGC ACATGGACCT CTGGGAAGAC GTCTGGCGAG GCTAGGCCC ACTGGCCCTA CAGACGGATC TTGCTGGCTC ACCTGTCCCT GTGGAGGTTC CCTGGGAAG GCAAGATGCC CAACAACAGC ACTGCTCTGT CATTGGCCAA TGTTACCTAC TCACCATGG AAATTTTCAT TGGACTCTGC GCCATAGTGG GCAACGTGCT GGTCATCTGC GTGGTCAAGC TGAACCCCAG

CCTGCAGACC ACCACCTTCT ATTTCATTGT CTCTCTAGCC TGGCTGACA TTGCTGTTGG GGTGCTGGTC ATGCCTTTGG CCATTGTTGT CAGCCTGGGC TCACAATCC ACTTCTACAG CTGCCTTTTT ATGACTTGCC TACTGCTTAT CTTTACCCAC CCTCCATCA TGTCCTTGCT GGCCATCGCT GTGGACCGAT ACTTGCGGGT CAAGCTTACC GTCAGGTAGC CTGCGGCGTG GGGTGGGCAG CAATTGAGGC AGCTGGGAAA TGAGGCTACA AGCCAGAGC-3' (FRAG NO _) (SEQ ID NO 12484) 5'-GGGCAATTTG TTAGTTATCC GCCGCCACCA AGACGCGGCA CGGCGCCTGG ACCGGAGGGG CCCCGCGCGG GCGCGAACTT TGGGCTCGGG CGAGTGGGTG GTGCTCCGCC CAGCCCGAGA CGGGCGGGCG CGCGGGCCAA TGGGTGCCGC CTCTTGGCCG CGGGGGGCCC CGACCCGTGG GTCCCGGCCA CCAGCGCCCC

AGCCCCGAGG CTCAGAAGCG GCAGGCGGAG GCGCGGTCCG GGCGCTATGG CCATGCCCGG CGGGTCTCAC GCGGCTGCCC CTCGCCCGGC GCGCCTTCGG TAGGGGGCGC CCGGGGCCCA GCTGGCCCGG CCATGCTGCT GGAGACACAG GACGCGCTGT ACGTGGCGCT GGAGCTGGTC ATCGCCGCGC TTTCGGTGGC GGGCAACGTG CTGGTGTGCG CCGCGGTGGG CACGGCGAAC ACTCTGCAGA CGCCCACCAA CTACTTCCTG GTGTCCCTGG CTGCGGCCGA CGTGGCCGTG GGGCTCTTCG CCATCCCCTT TGCCATCACC ATCAGCCTGG GCTTCTGCAC TGACTTCTAC GGCTGCCTCT TCCTCGCCTG CTTCGTGCTG GTGCTCACGC AGAGCTCCAT CTTCAGCCTT CTGGCCGTGG CAGTCGACAG ATACCTGGCC ATCTGTGTCC CGCTCAGGTA TAAAAGTTTG GTCACGGGGA CCCGAGCAAG AGGGGTCATT GCTGTCCTCT GGGTCCTTGC

CTTTGGCATC GGATTGACTC CATTCCTGGG GTGGAACAGT AAAGACAGTG CCACCAACAA CTGCACAGAA CCCTGGGATG GAACCACGAA TGAAAGCTGC TGCCTTGTGA AGTGTCTCTT TGAGAATGTG GTCCCCATGA GCTACATGGT ATATTTCAAT TTCTTTGGGT GTGTTCTGCC CCCACTGCTT ATAATGCTGG TGATCTACAT TAAGATCTTC CTGGTGGCCT GCAGGCAGCT TCAGCGCACT GAGCTGATGG ACCACTCGAG GACCACCCTC CAGCGGGAGA TCCATGCAGC CAAGTCACTG GCCATGATTG TGGGGATTTT TGCCCTGTGC TGGTTACCTG TGCATGCTGT TAACTGTGTC ACTCTTTTCC AGCCAGCTCA GGGTAAAAAT AAGCCCAAGT GGGCAATGAA TATGGCCATT CTTCTGTCAC ATGCCAATTC AGTTGTCAAT CCCATTGTCT ATGCTTACCG GAACCGAGAC TTCCGCTACA CTTTTCACAA AATTATCTCC AGGTATCTTC TCTGCCAAGC AGATGTCAAG

AGTGGGAATG GTCAGGCTGG GGTACAGCCT GCTCTCGGTG TGGGCCTATG ATCTAGGCTC TCGCCTCTTC CAGGAGAAGA TACAAATCCA CAAGAAACAA AGAGGACACG GCTGGTTTTC ATTGTGAAAG ATAGCTACAC CTCACAAGGA AATGGACTGC CTCTCTTGAG CACTTCCCTG GAGCTACCAC GTATCTAGCT AATATGTATG TGTCAGTAGT AGGCTCCAAG GATTGACAAA TATATTTATG ATCTATTCAG CTGCTTTTAC TGTGTGGATT ATGCCAACAG CTTGAATGGA TTCTAACAGA CTCTTTTGTT TTTAAAAGTC TGCCTTGTTT ATGGTGGAAA ATTACTGAAA CTATTTTACT GTGAAACAGT GTGAACTATT ATAATGCAAA TACTTTTTAA CTTAGAGGCA ATGGAAAAAT AAAAGTTGAC TGTACTAAAA ATG-3'(FRAG NO J(SEQ DD NO 11794)

5'-GBG CB TGC-3' (FRAG NO 1676) (SEQ DD NO 11060) 5'-TTG TTG GGC-3' (FRAG NO 1677) (SEQ DD NO 11061) 5'-TGC CTT CCC BGG G-3' (FRAG NO 1678) (SEQ DDNO 11062) 5'-GTT GTT GGG CAT CTT GCC-3' (FRAG NO 1679) (SEQ ID NO 9372) 5'-GTG GGC CTA GCT CTC GCC-3' (GRAG NO 1680) (SEQ DD NO 9374)

5'-ACA GAG CA TGC TGT TGT TGG GCA TCT TGC CTT CCC AGG G-3' (FRAG 982) (SEQ ID NO 10361) 5'-BCB GBG CB TGC TGT TGT TGG GCB TCT TGC CTT CCC BGG G-3' (FRAG 983) (SEQ DD NO 10362) 5'-CCC TTT TCT GGT GGG GTG-3' (FRAG 984) (SEQ ID NO 10363) 5'-GTG CTG TTG TTG GGC-3' (FRAG 985) (SEQ DD NO 10364) 5'-TTT CTT CTG TTC CC-3' (FRAG 986) (SEQ ID NO 10365)

5'-CCC TTT TCT GGT GGG GTG-3' (FRAG 987) (SEQ DD NO 10366) 5'-GTG CTG TTG TTG GGC-3' (FRAG 988) (SEQ DD NO 10367) 5'-TTT CTT CTG TTC CC-3' (FRAG 989) (SEQ DD NO 10368)

Human IgE Receptor ( Nucleic Acid and Antisense Oligonucleotide Fragments^') 5'-TTT CCC CTG GGT CTT CC CTC CTG CTC TTT TTT C ATT TGC TCT CCT ATT ACT TTC TGT GTC CAT TTT TTC ATT AAC CGA GCT GT BTT TGC TCT CCT BTT BCT

TTC TGT GTC CBT TTT TTC BTT BBC CGB GCT GT-3' (FRAG NO 1681) (SEQ DD NO 11063)

5'-CCC CTG GG-3' (FRAG NO 1682) (SEQ ID NO 11064)

5'-GCTCTCCTBTT-3' (FRAG NO 1683) (SEQ ID NO 11065)

5'-CBTTBBCCGBGCTG-3' (FRAG NO 1684) (SEQ ID NO 11066) 5'-TTT CCC CTG GGT CTT CC-3' (FRAG 990) (SEQ DD NO 10369)

5'-CTC CTG CTC TTTTTT C-3' (FRAG 991) (SEQ DD NO 10370)

ATTTGCTCTCCTATTACTTTCTGTGTCCATTTTTTCATTAACCGAGCTGT (FRAG 992) (SEQ DD NO 10371)

BTTTGCTCTCCTBTTBCTTTCTGTGTCCBTTTTTTCBTTBBCCGBGCTGT (FRAG 993) (SEQ DD O 10372)

Human Fc-f Receptor CD23 Antigen (IgE Receptor) Nucleic Acid and Antisense Oligonucleotide Fragments

5'-GCC TGT GTC TGT CCT CCT GCT TCG TTC CTC TCG TTC CTG CTT GGT GCC CTT GCC G GTC CTG CTC CTC CGG GCT GTG G GTC GTG GCC CTG GCT CCG GCT GGT GGG CTC CCC TGG CCT TCG CTG GCT GGC GGC GTG C GGG TCT TGC TCT GGG CCT GGC TGT GGC CGT GGT TGG GGG TCT TC GCT GCC TCC GTT TGG GTG GC TCT CTGAAT ATT GAC CTT CCT CCA TGG CGG TCC TGC TTG GAT TCT CCC GA TCT CTGBBT BTT GBC CTT CCT CCB TGGCGGTCC TGC TTG GBT TCT CCC GB-

3'(FRAG 1685)(SEQIDNO 11067)

5'-GT CCT CCT-3' (FRAG 1686) (SEQ DD NO 11068)

5'-TGT GTC TGT CCT CC-3' (FRAG 1687) (SEQ DD NO 11069) 5'-GTG GCC CTG GC-3' (FRAG 1688) (SEQ DD NO 11070)

5'-CGT GGT TGG GG-3' (FRAG 1689) (SEQ DD O 11071)

5'-TCT CTG BBT BTT GBC C-3' (FRAG1690) (SEQ DD NO 11072)

5'-GCC TGT GTC TGT CCT CCT-3' (FRAG 994) (SEQ DD NO 10373)

5'-GCT TCG TTC CTC TCG TTC-3' (FRAG 995) (SEQ DD NO 10374) 5'-CTG CTT GGT GCC CTT GCC G-3 ' (FRAG 996) (SEQ DD NO 10375)

5'-GTC CTG CTC CTC CGG GCT GTG G-3' (FRAG 997) (SEQ DD NO 10376)

5'-GTC GTG GCC CTG GCT CCG GCT GGT GGG CTC CCC TGG-3' (FRAG 998) (SEQ DD NO 10377)

5'-CCT TCG CTG GCT GGC GGC GTG C-3' (FRAG 999) (SEQ TD NO 10378)

5'-GGG TCT TGC TCT GGG CCT GGC TGT-3 ' (FRAG 1000) (SEQ DD NO 10379) 5'-GGC CGT GGT TGG GGG TCT TC-3' (FRAG 1001) (SEQ DD NO 10380)

5'-GCT GCC TCC GTT TGG GTG GC (FRAG 1002) (SEQ DD NO 10381)

5'-TCT CTG AAT ATT GAC CTT CCT CCA TGG CGG TCC TGC TTG GAT TCT CCC GA (FRAG 1003) (SEQ DD NO 10382)

5'-TCT CTG BBT BTT GBC CTT CCT CCB TGG CGG TCC TGC TTG GBT TCT CCC GB (FRAG 1004) (SEQ DD NO 10383)

Human IgE Receptor ( Subunit Nucleic Acid and Antisense Oligonucleotide Fragments 5'- GCC TTT CCT GGT TCT CTT GTT GTT TTT GGG GTT TGG CTT ACA GTA GAG TAG GGG ATT CCA TGG CAG GAG CCA TCT TCT TCA TGG ACT CC TTC AAG GAG

ACC TTA GGT TTC TGA GGG ACT GCT AAC ACG CCA TCT GGA GC BCB GTB GBG TBG GGG BTT CCB TGG CBG GBG CCB TCT TCT TCB TGG BCT CC TTC BBG GBG

BCC TTB GGT TTC TGB GGG BCT GCT BBC BCG CCB TCT GGB GC GTT GTT TTT GGG GTT TGG CTT GCC TTT CCT GGT TCT CTT BCB GTB GBG TBG GGG BTT CCB

TGG CBG GBG CCB TCT TCT TCB TGG BCT CC TTC BBG GBG BCC TTB GGT TTC TGB GGG BCT GCT BBC BCG CCB TCT GGB GC-3' (FRAG NO 1691) (SEQ DD

NO 11073) 5'- TGG BCT CC -3' (FRAG NO 1692) (SEQ ID NO U074)

5'-CCB TCT GGB-3' (FRAG NO 1693) (SEQ DD NO 11075)

5' CT GCT BBC BCG-3' (FRAG NO 1694) (SEQ DD NO 11076)

5'-GTT TTT GGG GTT TG-3' (FRAG NO 1695) (SEQ ED NO 11077)

5'-GCC TTT CCT GGT TCT CTT GTT GTT TTT GGG GTT TGG CTT-3' (FRAG NO 1005) (SEQ DD NO 10384) 5'-ACAGTAGAGTAGGGGATTCCATGGCAGGAGCCATCTTCTTCATGGACTCC-3'(FRAGNO 1006)(SEQ DDNO 10385)

5'-TTC AAG GAG ACC TTA GGT TTC TGA GGG ACT GCT AAC ACG CCA TCT GGA GC-3' (FRAG NO 1007) (SEQ ID NO 10386)

5'-BCB GTB GBG TBG GGG BTT CCB TGG CBG GBG CCB TCT TCT TCB TGG BCT CC TTC BBG GBG BCC TTB GGT TTC TGB GGG 3' (FRAG NO 1008) (SEQ DDNO 10387)

5'-BCT GCT BBC BCG CCB TCT GGB GC-3' (FRAG NO 1009) (SEQ DD NO 10388)

5'-GTT GTT TTT GGG GTT TGG CTT-3' (FRAG NO 1010) (SEQ ED NO 10389) 5 3CC TTT CCT GGT TCT CTT-3' (FRAG NO 1011) (SEQ ED NO 10390)

5'-BCBGTBGBGTBGGGGBTTCCBTGGCBGGBGCCBTCTTCTTCBTGGBCTCC-3'(FRAGNO 1012) (SEQ DD NO 10391)

5'-TTC BBG GBG BCC TTB GGT TTC TGB GGG BCT GCT BBC BCG CCB TCT GGB GC-3' (FRAG NO 1013) (SEQ DD NO 10392)

Human IgE Receptor fFc Epsilon R^") Nucleic Acid and Antisense Oligonucleotide Fragments

5'-GCC TGT GTC TGT CCT CCT GCT TCG TTC CTC TCG TTC CTG CTT GGT GCC CTT GCC G GTC CTG CTC CTC CGG GCT GTG G GTC CTC GCC CTG GCT CCG GCT GGT GGG CTC CCC TGG CCT TCG CTG GCT GGC GGC GTG C CCC BGB BCG BGB CCC GGB CCG BCB GGC CGT GGT TGG GGG TCT TC GCT GCC TCC GTT TGG GTG GC GAT

CTC TGA ATA TTGA CCT TCC ATG GCG GTC CTG CTT GGA GBT CTC TGB BTB TTGB CCT TCC BTG GCG GTC CTG CTT GGB-3' (FRAG 1696) (SEQ DD NO 11078)

5'-TCG TTC CTC TCG-3' (FRAG 1697) (SEQ DD NO 12370)

5'-BGB BCGBGB C-3' (FRAG 1698) (SEQ ID NO 11080)

5'-TGB BTB TTGB-3' (FRAG 1699) (SEQ D NO 11081) 5'-GCC TGT GTC TGT CCT CCT-3' (FRAG NO 1014) (SEQ DD NO 10393)

5'-GCT TCG TTC CTC TCG TTC-3' (FRAG NO 1015)(SEQ DDNO 10394)

5'-CTG CTT GGT GCC CTT GCC G-3' (FRAG NO 1016)(SEQ DD NO 10395)

5'-GTC CTG CTC CTC CGG GCT GTG G-3' (FRAG NO 1017)(SEQ DD NO 10396)

5'-GTC CTC GCC CTG GCT CCG GCT GGT GGG CTC CCC TGG-3' (FRAG NO 1018) (SEQ DD NO 10397) 5'-CCT TCG CTG GCT GGC GGC GTG C-3' (FRAG NO 1019) (SEQ ID NO 10398)

S'-CCC BGB BCG BGB CCC GGB CCG BCB-3' (FRAG NO 1020) (SEQ ID NO 10399)

5'-GGC CGT GGT TGG GGG TCT TC-3' (FRAG NO 1021) (SEQ ID NO 10400)

5'-GCT GCC TCC GTT TGG GTG GC-3' (FRAG NO 1022) (SEQ DDNO 10401)

5'-GBT CTC TGB BTB TTGB CCT TCC BTG GCG GTC CTG CTT GGB-3' (FRAG NO 1023) (SEQ DD NO 10402) Human High Affinity IgE Receptor Oligonucleotide Fragments

5'-AACAAGAAAA GCGTTGGTAG CTCTGGTGAA TCCCAAAAGA ATGTGGCAGT TGCTAGCCAT GCTCCTGAAT ATGTATAAAC AGTACATCAT ATGACTAAGA GTTTGACTTA GGGGTTAGAT TTTATGTGTT TGAACCCCAA ATTAGTTATT TAATAGTTGG CACCCCAAAA CAAGTTACTT AACCTCACTA AGGTTCAGTT TTCCTGTTTA TAAAATGTAG ATAGTGATAG TATGTACTTT ATAGGATTAT TGTGAAAAAT AAATGAAATA TCAGATTTAT TTAGGATAAC ACCTGGCATA TGTTTGGTAT TCAGAATTAG TTGCTGCTGT TTTATTCTGC TCTCCCTTGC ATCCCACTTT TCTAAGTTGT AAACTAAATA GTTGTACACA GATTGACAGA TTAAGAAAGG CTTGTGATTG TGCTAGACCT ATGCCTATGC CTCTGTCTCA CCAGATTCCA GGTGTATATG TGGAGGTGGG ATAGGGAGTG GAGTAAGTGG GTAAATATTA AATTGCCCAG TTGGGCACCA TCCTGAATAT

TATCTCTAAA GAAAGAAGCA AAACCAGGCA CAGCTGATGG GTTAACCAGA TATGATACAG AAAACATTTC CTTCTGCTTT TTGGTTTTAA GCCTATATTT GAAGCCTTAG ATCTCTCCAG CACAGTAAGC ACCAGGAGTC CATGAAGAAG ATG GATCTTCATG TGGAATGACT GGTTTCATTC AATAGACTTA ATTCAGCAGT CTGTGGGGAA GAGCAAGGTA TGATAGAATG GTTCCTCAAG TGCTTCAGAT GTGAAGTGGG TTTAAATATA CTGTCCCTGT CTTCTTCAGA GTTTTGGTAA AGATAAAATA GGACACTCAT TTAAAAGCAA TCTTTGCAAA TGACAAGCCA CTATAGACAT TAATAGAGTT TTCATTTCCA GTATTATCAT TAATATCAGA TCCTGGAAGA AGGTTGAGCC TTGACCTAGA GCAAAAAAAC AGAAGAATTA GTAAAGGAAT CCTGGAGAAA GCCCCTGCTG TGTATTTAAA GGAGAAAGGG AGATCATGTT GGGAAATTAT AATATTAAAA

GTAAACAAAA GCTAGGAAGT AAAATAAAAT AAATTATATG GCCTAGATCC CCATAAGTAA TGGTTTAACT TCTGCCTTCC TGTGTTCTGA GCCAGATTAG GGCACAGTAG AGAAAGAGGA GTCTCTGAAA ATGTTTCCAA TTTCGCTGGT CAGACAGCGG ATCATCAGTG AATCAGATGA AAATTTGTGG ATTTATGCAC TAACTGATCA GCAGGAAATT AAACAAGAAA AGCGTTGGTA GCTCTGGTGA ATCCCAAAAG AATTTGGCAG TTGCTAGCCA TGCTCCTGAA TATGTATAAA CAGTACATCA TATGACTAAG AGTTTGACTT AGGGGTTAGA TTTTATGTGT TTGAACCCCA AATTAGTTAT TTAATAGTTG GCACCCCAAA ACAAGTTACT TAACCTCACT AAGATTCAGT TTTCCTGTTT ATAAAATGTA GATAGTGATA GTATGTACTT TATAGGATTA TTGTGAAAAA TAAATGAAAT ATCAGATTTA TTTAGGATAA CACCTGGCAT ATGTTTGGTA TTCAGTAATT AGTTGCTGCT

GTTTTATTCT GCTCTCCCTT GCATCCCACT TTTCTAAGTT GTAAACTAAA TAGTTGTACA CAGATTGACA GATTAAGAAA GGCTTGTGAT TGTGCTAGAC CTATGCCTCT CTCTCACCAG ATTCCAGGTG TATATGTGGA GGTGGGATAG GGAGTGGAGT AAGTGGGTAA ATATTAAATT GCCCAGTTGG GCACCATCCT GAATATTATC TCTAAAGAAA GAAGCAAAAC CAGGCACAGC TGATGGGTTA ACCAGATATG ATACAGAAAA CATTTCCTTC TGCTTTTTGG TTTTAAGCCT ATATTTGAAG CCTTAGATCT CTCCAGCACA GTAAGCACCA GGAGTCCATG AAGAAGATGG CTCCTGCCAT GGAATCCCCT ACTCTACTGT GTGTAGCCTT ACTGTTCTTC GGTAAGTAGA GATTCAATTA CCCCTCCCAG GGAGGCCCAA ATGAATTTGG GGAGCAGCTG GGGTAGGAAC CTTTACTGTG GGTGGTGACT TTTTCTAGGA CATGTGCAAA CTATTGGGCA TTTCCCAGGG ACTCTGTAGT

GGAGCCAAGC TAGAAAOCAG AGGCAAGTGG GCTGAGCAAC ACCTAAGGAG GAAGCCAGAC TGAAAGCTTG GTTCCTTGCA TTTGCTCTGG CATCTTCCAG AGTGCAAATT TCCTACCAAG GTAATGAGGG TAGAGGAGAG AAAGAAGCTC TTTCTTCCCC TGATTCTCAT TCCTGAAAAG ACGGTTGGTC CTTAAAATTC CATGGATGTA GATCTTATCC CCACACCCAG ATTCTAGTCC TCTGGAGATA AAGAAGACTG CTGGACACTA ATGTATCCTC TCTGGACTTT TGCAGCTCCA GATGGCGTGT TAGCAGGTGA GTCCTCTGTT CTTGTTCCCT TGGTGTATCA ACATGTCTGG GCATTGCTTT CCTCTCACTA TTTTCTTCGT CCCATCACTT CTGCTTTCTA ATGAGCATGA ATCTGTTCCT TGOCCAGACT ACTTTCCCTC TCCACCTTGC CTTGTCTTTC TTTTTTTCCC TGATTCATTG CATTCTCTCA AGTCATTCTC TCCTCTGTTT TAGTCAATAA CCATGTCTGT TGCACATATA

CATGTCTCAT TCTCTCTCCT AGACACTTTG GCATGATCTC GCTCAATAAT TACATTATTA TTATTATTGC CATTTTATAA TTGAGGATGC TGAAACTCAG TGATTTTCTG GTGGTTACAT GGCTAAGGAA CTGGATTTCA ACGTAAGTTC CTTGGATCTA AGTCCAGTTC TCTTCTGACT ATATCACCCT TTTGTTATCA CCATGTATCT ACTTCTTTGG TCTCTGTTCA AATTTGCACT ACATCCCCTT GTTCCAGGAA GCCATTCAAG ACTGACTTTC TTAGTGCCTC TCACTACTTT CTGGAACTGA CATATGTTTT TCACTCTGTA TATACTTACA ATTAAATAGT CATAAATATT CAGAGCTTGG AGAAACCTTA TATTTCATCC AGTCCAGTAA ATTTATCCAT CCATAATTCA CTCATTCATT CACATAATAA ATATTTAATG TAACAATGGT TGAACATGGC AGACAGTGTT TCTACCTCAA AAGAGATTGC AGTCCTCATT TACAGATACT GAATTGAAAT TAACAGAAGT AGAGTGAGTC

AGCTCAAATC ACATAGTGAA TTGGTTTCTT TGTTTTTAAA TCTCCTGCAT ATGTGTCCTG TCTTTCTCCC TGTGTTGGGC GTTCCCTGGG GCACCAATAC TAATTTCTCC TTCCCCTAGA AATCAAAACA GGGTCTTATC ACCAACAGAA TAAGGACAGG TTGACCACTG ATTGTCAGAA TATTGCTTCG TTTGTACTTT TAAGCCTAGA CAGTTTTCAA TGACTTTTTT TCTCTCTACA TGTCTTTTCA TATTTTTATC TTCTTGAAGT CCCTCAGAAA CCTAAGGTCT CCTTGAACCC TCCATGGAAT AGAATATTTA AAGGAGAGAA TGTGACTCTT ACATGTAATG GGAACAATTT CTTTGAAGTC AGTTCCACCA AATGGTTCCA CAATGGCAGC CTTTCAGAAG AGACAAATTC AAGTTTGAAT ATTGTGAATG CCAAATTTGA AGACAGTGGA GAATACAAAT GTCAGCACCA ACAAGTTAAT GAGAGTGAAC CTGTGTACCT GGAAGTCTTC AGTGGTAAGT TCCAGGGATA TGGAAATACA

GATCTCTCAT GTGAGGGATG GCTCATCTGA AGATGGGAAA AAACAGGTTA TTCCAAGGGT TAGGACACCA GAGTGGGATT CAAGGCCTCT CATTTTTAAG ACCCCTGCAT TGGCTGGGCA CAGTGGCTCA CGCCTGTAAT CCCAGCACTT TGGGAGGCTG AGGCAGGTGG ATCACGAGGT CAGGAGATCG AGACCATCCG GCTAACATGG TGAAACCCCA TCTCTGCTAA AAAATATATA TATATAAAAT TAGCCGGGCG TAGTGGTGGG CACCTGTAGT CCCAGGTACT CGGGAGGCTG AGGCAGGAGA ATGGTGTGAA CCCAGGAGGT GGAGGTTGCA GTGAGCTGAG ATCACGCCAC TGCCCTCCAG CCTGGGCTAC AGAGCAAGAC TCCGTCTCAA AAAATAAATA AATAAATAAA AAAGACCCCT GCATCTCTTT TCTTCTACCC CCTTCCCTTT TATGCCTTCT TTCAATATTC TCAATATTAT TCCTCCACCC ATTTTCCTC TATCTTTTCT GCCTAGATTC

AGGTATATAT TATGTGGTCA AACAGCATGA CATATATGTG AACATTTCAA AGAGCTGTGT ATCTGGAATA GGATCAAAAG GTTTGACTTA AAGTTTTGCT CTGCATAATC CATATGGCAG GACCTGAATA TTAGGTTGTA CTCTTCGTTA TGAAACATAT CTGGGTACAT TTCCTTATGT CCTCTGTTGT TACTTAAGAA CACATATTTC ATGCTTGTTT CATTTTTATC ACTCCTACTG CCAACAAATA GCATAGCATG CTTAGGCACA TGTGGCTTAA TTAGCAAATG TTGAATAAAC AAATTAATGA TTTTGAATAG TGACCAATAG GTCTCTTTTA TACTCTATAT TTTTCTCTTG AGTGAAAAAA AATGTTTCAA CCTCCATATG TAAATTCCAA ACACAAACTA AAGCAATGTA GAATAGCTTC TTTATTCCCT GGAGTAGGTT CTAGAGAAGT CCTAAAGGAT TGGTCCTAAA TTAATTATGC TTATTATGCT AGCGATATTT CCTTTCAAAA TTCTCCTTTA ATGAATGCTT TTTAATTTTT ACAAAAGCAT TAACCATAGA ATGTGATTCT TGTCTTTCAC TGACTCATTA GTGACAAATA TTTGTTGAGT ACCTACCAAC TCCTAAGTAT TGCTACCAAC TCCTAAATAC TGTGTTGGGC ATTCAGAATA GAATGTAGAA CTAGACAGGG TCCCTGACTT CTTGGAGCAC AGAGCAGTAT GGGAAGAGGA CATTAAATAA AGAATTACAT AAGTAATTAA TTTAAATTAT ACATGTTTTG AAGAAGTTTT TTTTTGACAA CTATAATTAA CACTAGAACT GGGAAGTTTC TATAAGGTAA GAGAGGACAA AATAGACACT CTCCTAAGCT

AAAATTCCCA AGAAAGACTG TTTATTTTCC CCTAACTAAC TAGAACTAGC AACAGAAGAT CTGAAAGGAA TTCTGGCTTT CAAGTGTTCC ATGTATGGAC TCATCAGGGA GGTCCGAGAG GCTTTGTGGC CCCAGACTGA CTTTTCAGGA GGGGAAAGGA TTTATCAATA CACAAGACAG GCTCTAAGCA TTATTTTGTG CCCTTTAAAA ATCCACTTTA TGAGCCAAAA AGTGAGTTAA TGATAATTCA TAGTTTCTGA CACATGCTCT ATGCGTGGCT CTCTTTTCTC TATTCATTCT CTCTCTCTTC ATTTATTGTT AAATAAATAA TGTAATGAAT GTTCTTCAGA CTGGCTGCTC CTTCAGGCCT CTGCTGAGGT GGTGATGGAG GGCCAGCCCC TCTTCCTCAG GTGCCATGGT TGGAGGAACT GGGATGTGTA CAAGGTGATC TATTATAAGG ATGGTGAAGC TCTCAAGTAC TGGTATGAGA ACCACAACAT CTCCATTACA AATGCCACAG TTGAAGACAG TGGAACCTAC TACTGTACGG

GCAAAGTGTG GCAGCTGGAC TATGAGTCTG AGCCCCTCAA CATTACTGTA ATAAAAGGTG AGTTGGTAAA GGAAAGGAAA AGCATCCATA GCAGGGGAAG GAAGAGAGAA CTTCTGAGCC TGAGCAGTTG CAGCTTGTAG AAGGGGGGCA CCTGTGATAC ACTGGAAAGC CTACCAGACT TGCAATGAGG AGACCTGGGT GATAGTATAT ATCTCAATCT CTGTTTCAAA GCCTTGACTT GTTAAATGGT GATAGTAATA CCTGCTTGCA CTATGAAATT TTTATGAAGA TTAATGTGGT AATATTTGTG AAATGACTTT GTAAACTGTT AAGCACTACC CAAGCATAAC AGATTGTGAT TACTATTTTG ATCTCAAAGT CATCTGTTGC TCCTGGGGGA ACACTTATAT TTATCAAATT GAAAAAAAGT TTCAAAGTTG AATGAAGAAA GGATATAAAG AGCTTGAGGA GCCCATTCCA GCTTAGGAGG GCTGGGAAAG GAAACCAGCA AGTCAGTAAG

CTGTGTGCCT GTGTATTGAG GGAGGAGGGA ATGGACTTGA TATGGAGAGG GTAGGGAGGT GGACTGCCTC TATGGCCTGT AAGAAAAACT GCTCTCTCCA AACTCTTTAT AAGAGAGGGA GCCTGTGAAG TATTCACTTT TGAAGGAGAA AGTTAGACTT TTCCTTCACA CACTTTGTAC ATAATAATGT TTAAAAAAGC ATGAGGTCAA AATACATAAT TAAGTCCTAG CAGTTCTCTG TTAACTAATT TGAGACTGAA GTGCTATGTA CTTGTCTCTA GGCTTCCAGT ATCTTCATCT GTAAAACAGA ATATTTGGTC TAGATTCCAT TAGAATCATT TGATAACTTA AAAAATATAT TGATGCTCAT GTCTCATTTC TTGAGATTCT GATTTAATTG GTTTGGGGTG CAGCCTGGGT ATACGTATTT TTCATAGGTC TTTCACATAA TGGTAATGGG TAGCCAATAT TGAGAATCAC TTGTCTAGGT GATCTTTAAA TGATTTCTGG ATGTAATATT CTGAGGCTCT ATAATTTGAG ACTAATCACA

AAAATCGGTA CAGTTTATAA ACAGACTAAC AGAACCACAA AATAATAGAA TTGGAAGGCA ATTTAACTAG TGCAATTTCT TCATTTTGCC TAACAGGCAT GTAAGAAATG ATGATTGATT GAGTAATAGG CATTGATGAC CCCTGTCCTC ACTTTGTCCC CTTTCCACCC CTTAATTATA TGTGAATTCT GGTCTTGTCA TTTCGAATAA GGGGTTTATC TTTCCTATTG TCTTCCCCTC TGGGCACGGC ACACTGGCTA CTGGAGTTAA GAGGAAATGC TTAGGACTCC CTGTGGCTCC AGGGAGCACC AACAGAGCAA CTCAACCTAG TGTTAATCTG AGTGTTTTCT CTGTGCTTCT GGATGCCACA TCACGCTAAA AATGAAGGAC AAAGCTTGGT CTTTCTCTTA GGGAGGATGA AACTCTGAAC CTCATTTTTC AGTTCCCAAG ATGAATTATG TTTCTCATTG CATCTGTGTT CCACTACAGC TCCGCGTGAG AAGTACTGGC TACAATTTTT TATCCCATTG TTGGTGGTGA TTCTGTTTGC

TGTGGACACA GGATTATTTA TCTCAACTCA GCAGCAGGTC ACATTTCTCT TGAAGATTAA GAGAACCAGG AAAGGCTTCA GACTTCTGAA CCCACATCCT AAGCCAAACC CCAAAAACAA CTGATATAAT TACTCAAGAA ATATTTGCAA CATTAGTTTT TTTCCAGCAT CAGCAATTGC TACTCAATTG TCAAACACAG CTTGCAATAT ACATAGAAAC GTCTGTGCTC AAGGATTTAT AGAAATGCTT CATTAAACTG AGTGAAACTG GTTAAGTGGC ATGTAATAGT AAGTGCTCAA TTAACATTGG TTGAATAAAT GAGAGAATGA ATAGATTCAT TTATTAGCAT TTGTAAAAGA GATGTTCAAT TTCAATAAAA TAAATATAAA ACCATGTAAC AGAATGCTTC TGAGTATTCA AGGCTTGCTA GTTTGTTTGT TTGTTTTCTA CTAAAGGCAA GGACCATGAA GTTCTAGATT GGAAATGTCC TCTCTTGACT ATTGCAAGTG CGATCTAGGA ATGAAAAGAC ATAGGAGGAT GCCAGTGAGG

TGGATCATTT TTATGCTTCT TCTTCAGCTT ACTAAATATG AACTTTCAGT TCTTGGCAGA ATCAGGGACA GTCTCAAGAC ATAGGACTCT CAGGATGAAG TAGAGTCCAG GATTCCTCTG TGATTGTTTT GCCCCTCCCA AATTTATATC TTGAACTTAT GTCTTGTATC TTTATACAGC ACCTGAACCA AGCATTTTGG AGAAATTCCA GCTAATAATA ATAACCAAAA CCTTCGGCTC TGAAAACAGT CCAGGACTGA ATAAGATCTT GGGCAAAAGA ACTAGACAGT TTTGGTTTAT TTTCCCTTTC ATTTTATGTC TTCATCATAG TCATTGGAGG CTCATTCTTC TTGTCATGGA GTAAATGGGA TTAAAGTTC TACTAAGAGT CTCCAGCATC CTCCACCTGT CTACCACCGA GCATGGGCCT ATATTTGAAG CCTTAGATCT CTCCAGCACA GTAAGCACCA GGAGTCCATG AAGAAGATGG CTCCTGCCAT GGAATCCCCT ACTCTACTGT GTGTAGCCTT ACTGTTCTTC GCTCCAGATG

GCGTGTTAGC AGTCCCTCAG AAACCTAAGG TCTCCTTGAA CCCTCCATGG AATAGAATAT TTAAAGGAGA GAATGTGACT CTTACATGTA ATGGGAACAA TTTCTTTGAA GTCAGTTCCA CCAAATGGTT CCACAATGGC AGCCTTTCAG AAGAGACAAA TTCAAGTTTG AATATTGTGA ATGCCAAATT TGAAGACAGT GGAGAATACA AATGTCAGCA CCAACAAGTT AATGAGAGTG AACCTGTGTA CCTGGAAGTC TTCAGTGACT GGCTGCTCCT TCAGGCCTCT GCTGAGGTGG TGATGGAGGG CCAGCCCCTC TTCCTCAGGT GCCATGGTTG GAGGAACTGG GATGTGTACA AGGTGATCTA TTATAAGGAT GGTGAAGCTC TCAAGTACTG GTATGAGAAC CACAACATCT CCATTACAAA TGCCACAGTT GAAGACAGTG GAACCTACTA CTGTACGGGC AAAGTGTGGC AGCTGGACTA TGAGTCTGAG CCCCTCAACA TTACTGTAAT AAAAGCTCCG CGTGAGAAGT ACTGGCTACA

ATTTTTTATC CCATTGTTGG TGGTGATTCT GTTTGCTGTG GACACAGGAT TATTTATCTC AACTCAGCAG CAGGTCACAT TTCTCTTGAA GATTAAGAGA ACCAGGAAAG GCTTCAGACT TCTGAACCCA CATCCTAAGC CAAACCCCAA AAACAACTGA TATAATTACT CAAGAAATAT TTGCAACATT AGTTTTTTTC CAGCATCAGC AATTGCTACT CAATTGTCAA ACACAGCTTG CAATATACAT AGAAACGTCT GTGCTCAAGG ATTTATAGAA ATGCTTCATT AAACTGAGTG AAACTGGTTA AGTGGCATGT AATAGTAAGT GCTCAATTAA CATTGGTTGA ATAAATGAGA GAATGAATAG ATTCATTTAT TAGCATTTGT AAAAGAGATG TTCAATTTCA ATAAAATAAA TATAAAACCA TGTAACAGAA TGCTTCTGAG TAAAAAAAAA AAAAAAAAAA AAAAAAAA TCTCAATATA ATAATATTCT TTATTCCTGG ACAGCTCGGT TAATGAAAAA ATGGACACAG AAAGTAATAG

GAGAGCAAAT CTTGCTCTCC CACAGGAGCC TTCCAGTGTG CCTGCATTTG AAGTCTTGGA AATATCTCCC CAGGAAGTAT CTTCAGGCAG ACTATTGAAG TCGGCCTCAT CCCCACCACT GCATACATGG CTGACAGTTT TGAAAAAAGA GCAGGAGTTC CTGGGGGTAA CACAAATTCT GACTGCTATG ATATGCCTTT GTTTTGGAAC AGTTGTCTGC TCTGTACTTG ATATTTCACA CATTGAGGGA GACATTTTTT CATCATTTAA AGCAGGTTAT CCATTCTGGG GAGCCATATT TTTTTCTATT TCTGGAATGT TGTCAATTAT ATCTGAAAGG AGAAATGCAA CATATCTGGT GAGAGGAAGC CTGGGAGCAA ACACTGCCAG CAGCATAGCT GGGGGAACGG GAATTACCAT CCTGATCATC AACCTGAAGA AGAGCTTGGC CTATATCCAC ATCCACAGTT GCCAGAAATT TTTTGAGACC AAGTGCTTTA TGGCTTCCTT TTCCACTGAA ATTGTAGTGA TGATGCTGTT

TCTCACCATT CTGGGACTTG GTAGTGCTGT GTCACTCACA ATCTGTGGAG CTGGGGAAGA ACTCAAAGGA AACAAGGTTC CAGAGGATCG TGTTTATGAA GAATTAAACA TATATTCAGC TACTTACAGT GAGTTGGAAG ACCCAGGGGA AATGTCTCCT CCCATTGATT TATAAGAATC ACGTGTCCAG AACACTCTGA TTCACAGCCA AGGATCCAGA AGGCCAAGGT CTTGTTAAGG GGCTACTGGA AAAATTTCTA TTCTCTCCAC AGCCTGCTGG TTTT AAGCTTTTCA AAGGTGCAAT TGGATAACTT CTGCCATGAG AAATGGCTGA ATTGGGACAC AAGTGGGGAC AATTCCAGAA GAAGGGCACA TCTCTTTCTT TTCTGCAGTT CTTTCTCACC TTCTCAACTC CTACTAAAAT GTCTCATTTT CAGGTTCTGT AAATCCTGCT AGTCTCAGGC AAAATTATGC TCCAGGAGTC TCAAATTTTC TTATTTCATA TTAGTCTTTA TTTAGTAGAC TTCTCAATTT TTCTATTCAT

CACAAGTAAA AGCCTGTTGA TCTTAATCAG CCAAGAAACT TATCTGTCTG GCAAATGACT TATGTATAAA GAGAATCATC AATGTCATGA GGTAACCCAT TTCAACTGCC

, TATTCAGAGC ATGCAGTAAG AGGAAATCCA CCAAGTCTCA ATATAATAAT ATTCTTTATT CCTGGACAGC TCGGTTAATG AAAAAATGGA CACAGAAAGT AATAGGAGAG

CAAATCTTGC TCTCCCACAG GAGCCTTCCA GGTAGGTACA AGGTATTATT TTTTTCTACC CTCAGTCACT TGTGGCAGGG GAAGTCATAG TCACGGTGCT TAGGAGATGA

AACTTTATTG ATTTAGGCAT GGATCCATCT AGTTTAATTA ATATATTGGG TATGAGGAAG CTACTTGCTG TACTTTCCAT GTGGTTCTCT CTCCCTGGAG AGGAACATTT TTACTCAGCT TGCAAACTGG AAATAGATTT TCTCACATTA GAAGCTCATT TTCTGGGTAT GAGACAGGAG AGTTCATACT GTGTATGTAG ATCTCTGGCT TCTGGGTCTG

ACATGTGCTG AGGGACACAT ATCCTTCACA CATGCTTTTA TAAATACTTG ATAAAGTAAC CTGCTTCTTG ATTGGTCTTT ATAATCCATA AGCTGTGGGA TGCTTCTCTG AAGATGAAAA TAGTAATAGA GTCCCATCTA GCTATTCAAA GCCATTCCTT CATTGTATTC TGTGCACATG AAGTTGGGGT TTGTTACTGA CAAAATATAT TCAGATACAT TTCTATGTTA AAAGGATTGT GAGATGCATA GGTAAATGTG TTTATTTTCA GTTTTACTTG TCAACATAGA TGAATGAGAA AGAACTTGAA AGTAACACTG GATTAAGAAT AGGAAAATTT GGCATGGATT TTGCTCCATT TTGTCCCATC TAATCACTTG GATAGTGTTC AGGTGTTCTT GGTCAGTTAC TTGGATGCTC TGAGCTTTAG TTTCTTGGTG ATTACAATGA AGATTTGAAT TACAGGATGG CTTTGAAAAA ATAAACAAAA CTCCCCTTTC TGTCTGTCGA GAATGTTGCA CAGGGAGTTA CAGAATGTTC TCATGACTGA

ATTGCTTTTA AATTTCACAG TGTGCCTGCA TTTGAAGTCT TGGAAATATC TCCCCAGGAA GTATCTTCAG GCAGACTATT GAAGTCGGCC TCATCCCCAC CACTGCATAC ATGGCTGACA GTTTTGAAAA AAGAGCAGGA GTTCCTGGGG GTGAGTGAGC CTCCTCCAAC TTTGACTAGA GTAAGGGTTG GGTCTAGAAA AGAATATTGA GTTGCATCAA CTGTTTTCCC ACTTGGATTC ATGAGAGGTG TTAGGTCCTT TAAAAAACAT GGTAGATAAA GAGTTGACAC TAACTGGGTC CTTTTGGGAA GAGCCAGAAG CATTTCCTCA TAAAGACTTT AAATTGCTAG GACGAGAATG GCCAACAGGA GTGAAGGATT CATAACTTTA TCTTTACTTA GATGTAAAGA ACAATTACTG ATGTTCAACA TGACTACATA CATAAAGGCG CATGGAGAAA AGTATTGGCC TTCCATGCAT TAGGTAGTGC TTGTATCAAT TCTTATAGTG GCTAGGGTAT CCTGGAAAAT CTTACGTGTG GATCATTTCT

CAGGACAGTC TAGGACACTA ACGCAGTTTC TCATGTTTGG CTTCTATTAT TAAAAAATGA TACAATCTCG GGAAAATTTT TTTGATTTTC ATGAAATTCA TGTGTTTTTC TATAGGTAAC ACAAATTCTG ACTGCTATGA TATGCCTTTG TTTTGGAACA GTTGTCTGCT CTGTACTTGA TATTTCACAC ATTGAGGGAG ACATTTTTTC ATCATTTAAA GCAGGTTATC CATTCTGGGG AGCCATATTT GTGAGTATAT ATCTATAATT GTTTCTGAAA TAACACTGAA CATAGGTTTT TCTCTTTCTC AGATCTAACC AGTTGTTTAT TCCCAGTATT AAGATGATAT TTATAATTCT TAATTATAAA TATATGTGAG CATATATAAC ATAGATATGC TCATTAACAA CAACAAAAGA TTCTTTTTAC AATTAACGGT GGGTTAAACA TTTAGCCCAC AGTTTTATCC CATGAGAAAC CTGAATCTAA TACAAGTTAA ATGACTTGCC TAAGGGCCAC TTGACTAATA GTAATTGAAC CTAAACTTTC

AGAATCCAAC TCCAGGAACA TACTTCTAGC ACTATTCATC AATAAAGTTA TATGATAAAT ACATACAACT TTATCTGTCA ACTAAAAATA ACAACAGAGG CTGGGCATGG TGGCTCACAC CCGTAATCCC AGCACTTTGG GAGGCTGAGG CAGGTGGATC ACCTGAGGTC AGGAGTTTGA GACCAGCCTG ACCAACATGG TGAAACCTCA TCTCTACTAA ATATAAAAAA TTAGCTGAGT GTGATAGTGC ATACCTGTAA TCCAGCTACT TAAGAGGCTG AGGCAGGAGG CTTGTTTGAA CCTGGAAGGC AGAGGTTGCA GTGAGCTGAG ATTGTGCCAT TGCACTCCAG CCTGGGCAAT AAGTGCGAAC TCTGTCTCAA AATAATAATA ATAATAATAG AAAATAAAGT TGTCTTCATG AAAAATGAGG AAAGAGATTG CTGGGGTGAG AAACATTAAG ATCAATGGGC ATATGGTGAC CTTCTATGCC CTAGAAACTC TTTTANGGTA TTTTCTCCTG GTATCTCTTT TACNCATCGT TCTATCTGGA

AAAATAGGTG GATGAGTGAG ATAATAACGG TATATACTTT TTAAAGGTCT AATTGACATA TATAAATTGC AAGTATTTCA GATGTCAATT TGCTAACCTT GACACACATA GACACACATG AAAACATCAC CACATTAATA CAATGTATGT ATCCATCATT CCAAAAGCTT CCCTGTGTAT CTTTGTAACT CTTTCTTCCT CCCTCCACTC CTTGTCCTCT CGTTCCCAAG AAAACATTGA TCTGCTTCCT GTGAATATAA ATTAACTTAC ATTTTTTAGA GCTTTATATA AGTATGTTCT CTTTACTGTT TGTCTTCCTT CGCTGCACAG TTATTTTGAG ATTCTTCAAG TTTTTTCTTT ATATCGATAC TTCATTCACA AGAATATATT TTAATTCTAG ACTATGTCAC ATTGACTTTG TCGTCTGCTA AATCCTTAGT GCTCAGATGA CTTGTTCAGG ACTCTCCTTG AACCTGTACC TCTGTTANAT TGAAACTTGT CTCTACTGTC TTTTTATTTC AAACACAGCT TATTAGGTGT CTCTCAACCC

ATCAAACNCA CAATCTGAGT CTTTAGGAGA TTGCTTTGAA TTTGTGCTAT TGACTTATAT NTATATNAAA TNTGTAAATG TTTGGTAAAA ATATCATCAT GTACNTTTTC ATAATTACGC TATNTNCACA TGATATATGT CAGACTCTGG AAATATGCAT GCCACAGACA CGTGTTTCTT GCCTAAAGGG GCTGATGGAA GACNCACATA CNAATAGACG ATTGCAGTAG AATGAGAGTG GTGGTCTAAN CAGTACATGT CCTGATGTTG CTCGGACAGT TACTACNCCA AGAGTACCCC CTGCATTGTC AGGGTTAGCA TCTCCTGGAA GCCTCATGTA AATGAAGAAT TTCATGCTCC ATCCAGGACC TAATGAATAA GAATCTGCAT TTTAGCAAGA CCCTCATATG ATTCATATAC ACTTTTTTTT TTTTTTTTTA GATGGAGTCT CACTCTTGTC GCCCAGGCTG GAGTGCAATG GCATGATCTT GGCTCACTGC AACCTCTGCC TCCCGGGTTC AAGTGATTCT CCTGTCTCAG CCTCCCTAGT

AGCTGGGACT ACAGGTGCAT GCCACAGTGG CTGGCTAATT TTTGTATTTT TAGTAGAGAC AGGGTTTCAC CATTTTGGTC AGGCTGGTCT TGAACTCATG ACCTCCGGTG ATTCCCCCGC CTCGGCTTCC CAAAGTGCTG GGATTACAGA CATGAGCCAC CACACCCGCC TTATTCGTAT ACNCATTTAA TTCTGAGAAG CACTCTATAG AAAATAAGAA TAAGAAAATA TTGGGCTCAC AGGTGACATT AATAAGTAAC TTTATCGAGT ACCCCAAATT TTACCTATGT TTGGAAGATG GGGTTAAAAG GACACATTGA AAACAAGAAC TCATTGTGGC TTTTTTTTCC TCCTTTTTGA ACAGTTTTCT ATTTCTGGAA TGTTGTCAAT TATATCTGAA AGGAGAAATG CAACATATCT GGTGAGTTGC CCGTTTCTGT CTTTGTCCAT CCTTGAAAAG ATAAGAAGAA CAGAGTTTTA AGAGTCTTAA GGGAAACACA TCTTTGTCTC CTATATTACT TGTGAATGTG GATATATGAT TTTGTTTCAA

TCTATTTTGT GTCCTAAGGC TTTTTGCAAC AGAAGTTGGA TATATCATTA GAAACATAAA TTGTACCATT TAACATACAT GAAGTTTATG TTTACCTTGA CGTTCTTCTA AAAAGTGTCC TACACCGGCA TTGTCCTTGT AGGCATATTC ACATGATCAA ATAAAATAAT TAGTTTTCAA TTAAGGAGAA TATTTGAGGA AAGACCGTAC GTGTTCATGT GGTTCCTGAA GGCAGTCCAG TGAGAAAGTA ATATATGCTT CATTAAACAA TGCGGACATT TTCAGGGTTT CCCTTTTTAA CCAAAATTTG GAAGCAATGT GGAATTTACT GGATGCATCC AGCCCTGAAA TGAAGATAGG TTTATTGAAT GTGCCAGCAA GTGCAGGCCC AGGTCTGAGT GTTCTTCATT ATTATCAGGT GAGAGGAAGC CTGGGAGCAA ACACTGCCAG CAGCATAGCT GGGGGAACGG GAATTACCAT CCTGATCATC AACCTGAAGA AGAGCTTGGC CTATATCCAC ATCCACAGTT GCCAGAAATT TTTTGAGACC AAGTGCTTTA TGGCTTCCTT TTCCACTGTA TGTATTTTTT TTTGTGTGGG AAGACTAAGA TTCTGGGTCC TAATGTAAGT AAGAAGCCCT CTTCTCCTGT TCCATGAACA CCATCCTTTT CTGTAACTTC TATTACACAG TATAGTGGTT CTGTAAGTTC ACACAGCCCA GGGAGATGCT GGCTGCCCAC TCCCCTCAAC CCAGGCAAAT TCCTCGGGGT TAAAGTTATC TACTGCAAGT GACGATCTCT GGGTTTTTCT GTGCCTGTGT TTGTGTGTGT GTGTGTGTGT GTGTGTGTGT GTATGTGTCA CTTTAAAAGG ACTGGTCAGA TGGTAGGGAG ATGAAAACAG GAGATGCTAT AAGAAAATAA ACTTTTGGGG CGAATACCAA TGTGACTCTT TTTGTTTGTC ATTTGTTGCT GTTCAATAGG AAATTGTAGT

GATGATGCTG TTTCTCACCA TTCTGGGACT TGGTAGTGCT GTGTCACTCA CAATCTGTGG AGCTGGGGAA GAACTCAAAG GAAACAAGGT AGATAGAAGC CCGATATAAA ATCTTGAATG ACAGGTTAAC GAATTGGAGC TTTATTCCTT AAAATATGGC CTGGGTTTTC TGAAACATTT CTTCCAGAAA ATAGTTTCTC CAAGTTTTAT TACTTTGGTT TACAAATCTC ACATTTAAAT CACATTTTAT ACCATAAGTA GCACACATTT CATAATATTC CTCTGAATGA GGGTTGGGAT AATAGGACTG ATATGTTAGA AATGCCTTAA AGTGTGTGGA GCATGAGAGA TGGATGTACA GAAGGCTTGT GAGGAAACCA CCCAGGTATC TGGCCTTGTT TTCTGCCCCA GAACTAGCCG CCTATTCCTG TTTCTGTTTT ATTCCTTTGT TTCTTGACTT TTCCTTTCCA ACTTGCTCTA AAACCTCAGT TTTCTTTCCT TTCTGATTCA TGACTACCAA ATGTTTTCAC TTGCCTCACC CGTCCATTAC

ACCTTTGATA AGAACCACCA GACCTTGTGC TCATGTACTT GCCCATGTCT GATGGAAGAA ACATACTCTC TCCATCTGTC CACTTTCCTG AGGCATTCAA GTCTAGCCAC CTTTTAAAAT CACTCTCCTC CAGGCTGGGC ACGGTGTCAC GCCTGTAATC TCAGCACTTT GTGAGGCTGA GGAGGGCGGA TCACTTGAAG TCAGGAGTTC AAAACCAGCC TGGCCAAATG GCAAAACCAA ATCTTCTTCA ATTATAACCA AATCTTAAAC CAAATCTCTA CTAAAAAATA CAACAAAACA AAACAACAAC AACAAAAACA GAAAAGGAAA CATTAGCCCA GCGTGGTGGC AGGTACCTGA GGTTCCAGAT ACTTGGGAGG CTGAAGCAGG AGAATCGCTT GAGCCCAAGA GATGGAGGTT GCAGTGAGCC GAGATCATGC CACTGCACCA CAGCCAGGGT GACAGAGCCA TACTTCCCAG CACATTGGGA GGCCAAAGCT GAAGAATAAT TTGAGGTGAG GATTTGGAGA CCAGCCTGGC

CAACATGGTG AAACTCCGTC TGTACTAAAA ATATAAAACT TAGTGGGGCA TGGGGGCACA CACCTGTAAT TTCAGCTACT TAGGAGGCTG AGGCAGGAGA ATTGCTTGAA CCCGGGAGGC GGAAGTTGCA GTGAGCCAAG ATCGTGGCCA CTGCACTCCA GCCTGGGTGA CATAGTGAGA TTCTGTCTCA AAAAAAATAA AAGAAATTTA AAAAATCACT CTCTTCCAAA GATAGATAAA TAAGACAGCA GATATACTAA GGAATAACCT CACCAACTTG TCATTGACTG ACATGATTTC TTTTGGCCCA CTTGGCCAGC TAGTCTGGTT TGGTTTTCTG GAAATGAAAG AAATAATCAG AGTTTAATGA CAGAGAGCGT GAGACCCAGA AAGACAAAAG TAGATGAGGT AAGTCTCTTG AGCGAGACTT CTAGGGATGG GAAATTTGTG GTGATTGATA TGAAATGATT TTTCCCTTAT CAGGTTCCAG AGGATCGTGT TTATGAAGAA TTAAACATAT ATTCAGCTAC TTACAGTGAG

TTGGAAGACC CAGGGGAAAT GTCTCCTCCC ATTGATTTAT AAGAATCACG TGTCCAGAAC ACTCTGATTC ACAGCCAAGG ATCCAGAAGG CCAAGGTTTT GTTAAGGGGC TACTGGAAAA ATTTCTATTC TCTCCACAGC CTGCTGGTTT TACATTAGAT TTATTCGCCT GATAAGAATA TTTTGTTTCT GCTGCTTCTG TCCACCTTAA TATGCTCCTT CTATTTGTAG ATATGATAGA CTCCTATTTT TCTTGTTTTA TATTATGACC ACACACATCT CTGCTGGAAA GTCAACATGT AGTAAGCAAG ATTTAACTGT TTGATTATAA CTGTGCAAAT ACAGAAAAAA AGAAGGCTGG CTGAAAGTTG AGTTAAACTT TGACAGTTTG ATAATATTTG GTTCTTAGGG χ_Tχχχχχχχχ XTXXAGCATT CTTAATAGTT ACAGTTGGGC ATGATTTGTA CCATCCACCC ATACCCACAC AGTCACAGTC ACACACACAT ATGTATTACT TACACTATAT ATAACTTCCT ATGCAAATAT TTTACCACCA

GTCAATAATA CATTTTTGCC AAGACATGAA GTTTTATAAA GATCTGTATA ATTGCCTGAA TCACCAGCAC ATTCACTGAC ATGATATTAT TTGCAGATTG ACAAGTAGGA AGTGGGGAAC TTTTATTAAG TTACTCGTTG TCTGGGGAGG TAAATAGGTT AAAAACAGGG AAATTATAAG TGCAGAGATT AACATTTCAC AAATGTTTAG TGAAACATTT GTGAAAAAAG AAGACTAAAT TAAGACCTGA GCTGAAATAA AGTGACGTGG AAATGGAAAT AATGGTTATA TC AAAACAT GTAGAAAAAG AGTAACTGGT AGATTTTGTT AACAAATTAA AGAATAAAGT TAGACAAGCA ACTGGTTGAC TAATACATTA AGCGTTTGAG TCTAAGATGA AAGGAGAACA CTGGTTATGT TGATAGAATG ATAAAAAGGG TCGGGCGCGG AGGCTCACGC CTGTAATCCC AGCCCTTTGG GAGGCCGAGG TGGGCAGATC ACGAAGTCAG TAGTTTGAGA CCAGCCTGGC CAACATAGTG AAACCCCGTC

TCTACTAAAA ATACAAAAAA AAAATTAGCT GGGTGTGGTG GCAGTCACCT GTAGTCCCAG CTACTTGGGA GGATGAGGCA GGAGAATCGC TTGAACCTGG GAGGCGGAGG TTGCAGTGAG CCGAGATCGC ACCAGTGCAC TCCAGCCTTG GTGACAATGG GAGACTCCAT CTCAAAAAAA AAAAAAAAAA AAAAAAGATA AAAAGTCAGA AATCTGAAAA GTGGAGGAAG AGTACAAATA GACCTAAATT AAGTCTCATT TTTTGGCTTT GATTTTGGGG AGACAAAGGG AAATGCAGCC ATAGAGGGCC TGATGACATC CAATACATGA GTTCTGGTAA AGATAAAATT TGATACACGG TTTGGTGTCA TTATAAGAGA AATCATTATT AAATGAAGCA AGTTAACACT CTAAGAGAAT TATTTTGAGA TAGAAGTGAA GCTAAGCTAA ACTTCACATG CCTATAATTG GAGGGAAAAA CTAAGGATAA AATCTAGCCT AGAAGATACA ATAATTAGTC ATAAACATGC

ATTGTGAAAC TGTAGAGAGC AGGTAGCCCA AAATAGAGAA AGATTAGATA AAGAGAAAAT AAGTATCCAT CAGAGACAGT ATCTCTAGGC TTGGGCAAGA GAAAAGTCCA CAGTGATAAG CAACTCCACC TAAGGCATGA ATATGCGGCA GAGAAAACAG CAATAGTGAA TGAATGCAAA AGGTGCTGAG CAAATTCCAC ACATGAGTAT TGTGCATGAG TAAATGAATA AAACATTTGC AAAGACCTTT AGAGAAAGAG AATGGGAGCA TATGTGCGAA ATAAGATAGT TGATTATGAA TAGAAGGTAG TGAAGAAAAG CAAGCTAAGA AAAAATTCTG TTTATAAAAG AAGGAAAAGA TAGTTTATGT TTTTAGCCTA AGTATAAGAG TCCTACAGAT GGACTGAAAA AAATCAGTCT GAGAGTATTA GTCACAATTA ATGAAATAAT TACATTTTAT GTATTGAGGA TGCCAAGATT AAAAGGTGAC AGGTAGATGT TAATTTCCCT AGATTGTGAA AGTGATCACG

ACAATCACAC AACAAATAAT TAAGTGACTT GGTATGCTTT ATTTAATTGT AGGGCCTGAG GTTTTCCATT CTCATTTTTC TAAAATACAA TTTTGTTTCT CCAAATTTGA CAGCAGAATA AAAACCCTAC CCTTTCACTG TGTATCATGC TAAGCTGCAT CTCTACTCTT GATCATCTGT AGGTATTAAT CACATCACTT CCATGGCATG GATGTTCACA TACAGACTCT TAACCCTGGT TTACCAGGAC CTCTAGGAGT GGATCCAATC TATATCTTTA CAGTTGTATA GTATATGATA TCTCTTTTAT TTCACTCAAT TTATATTTTC ATCATTGACT ACATATTTCT TATACACAAC ACACAATTTA TGAATTTTTT CTCAAGATCA TTCTGAGAGT TGCCCCACCC TACCTGCCTT TTATAGTACG CCCACCTCAG GCAGACACAG AGCACAATGC TGGGGTTCTC TTCACACTAT CACTGCCCCA AATTGTCTTT CTAAATTTCA ACTTCAATGT CATCTTCTCC ATGAAGACCA CTGAATGAAC

ACCTTTTGAT CCAGCCTTAA TTTCTTGCTC CATAACTACT CTATCCCACG ATGCAGTATT GTATCATTAA TTATTAGTGT GCTTGTGACC TCCTTATGTA TTCTCAATTA CCTGTATTTG TGCAATAAAT TGGAATAATG TAACTTGATT TCTTATCTGT GTTTGTGTTG GCATGCAAGA TTTAGGTACT TATCAAGATA ATGGGGAATT AAGGCATCAA TAAAATGATG CCAAAGACCA AGAGCAGTTT CTGAAGTCCT CCTTTTCATC AGCTCTTTAT CAAACAGAAC ACTCTATAAA CAACCCATAG CCAGAAAACA GGATGTAGGA ACAATCACCA GCACACTCTA TAAACAACCC ATAGCCAGAA AACAGAATGT AAGGACAATC ACCAGCCATC TTTTGTCAAT AATTGATGGA ATAGAGTTGA AAGGAACTGG AGCATGAGTC ATATTTGACC AGTCAGTCCT CACTCTTATT TACTTGCTAT GTAAACTTGA GAAAGCTTTT TTCTCTTTGT GAACCTCAGG TTTTACATCT GAAAATGAGA

AATTTGGAAC AAAAGATTCC TAACTGGTCT TTCTGTTCCC ATATTCTGTG ATTTTTCAAT ATTTAGGATT TTTGGTAATC ACAATTACTT AGTTTGTGGT TGAGATAGCA ACACGAATCA GAACTATTTG GTGGACATAT TTTCAAAGGA GTAGCTCTCC ACTTTGGGTA AAGAAGTGAT GCNGGTCGTG GTGGCTCACG CCTGTAATCC CAGCACTTTA GGGAGGCCAA GGCGGGTGGA TCACGAGGTC AGGAGATCGA GACCATCCTG GCTAACACGG TGAAACCCCG TCTCTACTAA AAAATACAAA AAATTAGCCA GGCGTGGTGG CGGGCGCCTG TAGTCCCACG TACTCGGGAG GCTGAGGCAG GAGAATGGCA TGAACCAGGG AGGCGGAGCT TGCCGTGAGC CGAGATAGCG CCACTGCAGT CCCTCCTGGG CAAAAGAGCA AGACTGCGTC TCAAAAAAAA AAAAAAAAAA AAAAAAAGAA GTGTGTGGAG TAGCAGGACA CCTGCAACAA

TAATATTTTT CTAAATCCCT CTGAAAAATG CTAATCAAAG GGTTTTTTTC CTAAAAATTG TCTTAGAAAT AAAATTTCCC CTTTGGGAGA CCGAGGCTGG CAGATCACGA GGTCAGGAGA TAGAGACCAC GGTGAAACCC CGTCTCT ACT AAAAAT ACT A AAAATTAGCC GGGGNGTGGT GGTGGGTAC A CCTGT AGTCC C AGCT ACTTG GAGGCTGAGG CTGGAGAATCACGTGAAC-3' (FRAG NO J(SEQ DDNO 11874) 5'-AACAAGAAAA GCGTTGGTAG CTCTGGTGAA TCCCAAAAGA ATGTGGCAGT TGCTAGCCAT GCTCCTGAAT ATGTATAAAC AGTACATCAT ATGACTAAGA GTTTGACTTA GGGGTTAGAT TTTATGTGTT TGAACCCCAA ATTAGTTATT TAATAGTTGG CACCCCAAAA CAAGTTACTT AACCTCACTA AGGTTCAGTT TTCCTGTTTA

TAAAATGTAG ATAGTGATAG TATGTACTTT ATAGGATTAT TGTGAAAAAT AAATGAAATA TCAGATTTAT TTAGGATAAC ACCTGGCATA TGTTTGGTAT TCAGAATTAG TTGCTGCTGT TTTATTCTGC TCTCCCTTGC ATCCCACTTT TCTAAGTTGT AAACTAAATA GTTGTACACA GATTGACAGA TTAAGAAAGG CTTGTGATTG TGCTAGACCT ATGCCTATGC CTCTGTCTCA CCAGATTCCA GGTGTATATG TGGAGGTGGG ATAGGGAGTG GAGTAAGTGG GTAAATATTA AATTGCCCAG TTGGGCACCA TCCTGAATAT TATCTCTAAA GAAAGAAGCA AAACCAGGCA CAGCTGATGG GTTAACCAGA TATGATACAG AAAACATTTC CTTCTGCTTT TTGGTTTTAA GCCTATATTT GAAGCCTTAG ATCTCTCCAG CACAGTAAGC ACCAGGAGTC CATGAAGAAG ATG-3' (FRAG NO J(SEQ ID NO 11869)

5'-GATCTTCATG TGGAATGACT GGTTTCATTC AATAGACTTA ATTCAGCAGT CTGTGGGGAA GAGCAAGGTA TGATAGAATG GTTCCTCAAG TGCTTCAGAT GTGAAGTGGG TTTAAATATA CTGTCCCTGT CTTCTTCAGA GTTTTGGTAA AGATAAAATA GGACACTCAT TTAAAAGCAA TCTTTGCAAA TGACAAGCCA CTATAGACAT TAATAGAGTT TTCATTTCCA GTATTATCAT TAATATCAGA TCCTGGAAGA AGGTTGAGCC TTGACCTAGA GCAAAAAAAC AGAAGAATTA GTAAAGGAAT CCTGGAGAAA GCCCCTGCTG TGTATTTAAA GGAGAAAGGG AGATCATGTT GGGAAATTAT AATATTAAAA GTAAACAAAA GCTAGGAAGT AAAATAAAAT AAATTATATG GCCTAGATCC CCATAAGTAA TGGTTTAACT TCTGCCTTCC TGTGTTCTGA GCCAGATTAG GGCACAGTAG AGAAAGAGGA GTCTCTGAAA ATGTTTCCAA TTTCGCTGGT CAGACAGCGG

ATCATCAGTG AATCAGATGA AAATTTGTGG ATTTATGCAC TAACTGATCA GCAGGAAATT AAACAAGAAA AGCGTTGGTA GCTCTGGTGA ATCCCAAAAG AATTTGGCAG TTGCTAGCCA TGCTCCTGAA TATGTATAAA CAGTACATCA TATGACTAAG AGTTTGACTT AGGGGTTAGA TTTTATGTGT TTGAACCCCA AATTAGTTAT TTAATAGTTG GCACCCCAAA ACAAGTTACT TAACCTCACT AAGATTCAGT TTTCCTGTTT ATAAAATGTA GATAGTGATA GTATGTACTT TATAGGATTA TTGTGAAAAA TAAATGAAAT ATCAGATTTA TTTAGGATAA CACCTGGCAT ATGTTTGGTA TTCAGTAATT AGTTGCTGCT GTTTTATTCT GCTCTCCCTT GCATCCCACT TTTCTAAGTT GTAAACTAAA TAGTTGTACA CAGATTGACA GATTAAGAAA GGCTTGTGAT TGTGCTAGAC CTATGCCTCT CTCTCACCAG ATTCCAGGTG TATATGTGGA GGTGGGATAG GGAGTGGAGT

AAGTGGGTAA ATATTAAATT GCCCAGTTGG GCACCATCCT GAATATTATC TCTAAAGAAA GAAGCAAAAC CAGGCACAGC TGATGGGTTA ACCAGATATG ATACAGAAAA CATTTCCTTC TGCTTTTTGG TTTTAAGCCT ATATTTGAAG CCTTAGATCT CTCCAGCACA GTAAGCACCA GGAGTCCATG AAGAAGATGG CTCCTGCCAT GGAATCCCCT ACTCTACTGT GTGTAGCCTT ACTGTTCTTC GGTAAGTAGA GATTCAATTA CCCCTCCCAG GGAGGCCCAA ATGAATTTGG GGAGCAGCTG GGGTAGGAAC CTTTACTGTG GGTGGTGACT TTTTCTAGGA CATGTGCAAA CTATTGGGCA TTTCCCAGGG ACTCTGTAGT GGAGCCAAGC TAGAAAGCAG AGGCAAGTGG GCTGAGCAAC ACCTAAGGAG GAAGCCAGAC TGAAAGCTTG GTTCCTTGCA TTTGCTCTGG CATCTTCCAG AGTGCAAATT TCCTACCAAG GTAATGAGGG TAGAGGAGAG AAAGAAGCTC TTTCTTCCCC

TGATTCTCAT TCCTGAAAAG ACGGTTGGTC CTTAAAATTC CATGGATGTA GATCTTATCC CCACACCCAG ATTCTAGTCC TCTGGAGATA AAGAAGACTG CTGGACACTA ATGTATCCTC TCTGGACTTT TGCAGCTCCA GATGGCGTGT TAGCAGGTGA GTCCTCTGTT CTTGTTCCCT TGGTGTATCA ACATGTCTGG GCATTGCTTT CCTCTCACTA TTTTCTTCGT CCCATCACTT CTGCTTTCTA ATGAGCATGA ATCTGTTCCT TGGCCAGACT ACTTTCCCTC TCCACCTTGC CTTGTCTTTC TTTTTTTCCC TGATTCATTG CATTCTCTCA AGTCATTCTC TCCTCTGTTT TAGTCAATAA CCATGTCTGT TGCACATATA CATGTCTCAT TCTCTCTCCT AGACACTTTG GCATGATCTC GCTCAATAAT TACATTATTA TTATTATTGC CATTTTATAA TTGAGGATGC TGAAACTCAG TGATTTTCTG GTGGTTACAT GGCTAAGGAA CTGGATTTCA ACGTAAGTTC CTTGGATCTA

AGTCCAGTTC TCTTCTGACT ATATCACCCT TTTGTTATCA CCATGTATCT ACTTCTTTGG TCTCTGTTCA AATTTGCACT ACATCOCCTT GTTCCAGGAA GCCATTCAAG ACTGACTTTC TTAGTGCCTC TCACTACTTT CTGGAACTGA CATATGTTTT TCACTCTGTA TATACTTACA ATTAAATAGT CATAAATATT CAGAGCTTGG AGAAACCTTA TATTTCATCC AGTCCAGTAA ATTTATCCAT CCATAATTCA CTCATTCATT CACATAATAA ATATTTAATG TAACAATGGT TGAACATGGC AGACAGTGTT TCTACCTCAA AAGAGATTGC AGTCCTCATT TACAGATACT GAATTGAAAT TAACAGAAGT AGAGTGAGTC AGCTCAAATC ACATAGTGAA TTGGTTTCTT TGTTTTTAAA TCTCCTGCAT ATGTGTCCTG TCTTTCTCCC TGTGTTGGGC GTTCCCTGGG GCACCAATAC TAATTTCTCC TTCCCCTAGA AATCAAAACA GGGTCTTATC ACCAACAGAA TAAGGACAGG

TTGACCACTG ATTGTCAGAA TATTGCTTCG TTTGTACTTT TAAGCCTAGA CAGTTTTCAA TGACTTTTTT TCTCTCTACA TGTCTTTTCA TATTTTTATC TTCTTGAAGT CCCTCAGAAA CCTAAGGTCT CCTTGAACCC TCCATGGAAT AGAATATTTA AAGGAGAGAA TGTGACTCTT ACATGTAATG GGAACAATTT CTTTGAAGTC AGTTCCACCA AATGGTTCCA GAATGGCAGC CTTTCAGAAG AGACAAATTC AAGTTTGAAT ATTGTGAATG CCAAATTTGA AGACAGTGGA GAATACAAAT GTCAGCACCA ACAAGTTAAT GAGAGTGAAC CTGTGTACCT GGAAGTCTTC AGTGGTAAGT TCCAGGGATA TGGAAATACA GATCTCTCAT GTGAGGGATG GCTCATCTGA AGATGGGAAA AAACAGGTTA TTCCAAGGGT TAGGACACCA GAGTGGGATT CAAGGCCTCT CATTTTTAAG ACCCCTGCAT TGGCTGGGCA CAGTGGCTCA CGCCTGTAAT CCCAGCACTT TGGGAGGCTG

AGGCAGGTGG ATCACGAGGT CAGGAGATCG AGACCATCCG GCTAACATGG TGAAACCCCA TCTCTGCTAA AAAATATATA TATATAAAAT TAGCCGGGCG TAGTGGTGGG CACCTGTAGT CCCAGGTACT CGGGAGGCTG AGGCAGGAGA ATGGTGTGAA CCCAGGAGGT GGAGGTTGCA GTGAGCTGAG ATCACGCCAC TGCCCTCCAG CCTGGGCTAC AGAGCAAGAC TCCGTCTCAA AAAATAAATA AATAAATAAA AAAGACCCCT GCATCTCTTT TCTTCTACCC CCTTCCCTTT TGATTACTTG TATGCCTTCT TTCAATATTC TAGTCATCTC TCAATATTAT TCCTCCACCC TATTTTCCTC TATCTTTTCT GCCTAGATTC AGGTATATAT TATGTGGTCA AACAGCATGA CATATATGTG AACATTTCAA AGAGCTGTGT ATCTGGAATA GGATCAAAAG GTTTGACTTA AAGTTTTGCT CTGCATAATC CATATGGCAG GACCTGAATA TTAGGTTGTA CTCTTCGTTA TGAAACATAT CTGGGTACAT TTCCTTATGT CCTCTGTTGT TACTTAAGAA CACATATTTC ATGCTTGTTT CATTTTTATC ACTCCTACTG CCAACAAATA GCATAGCATG CTTAGGCACA TGTGGCTTAA TTAGCAAATG TTGAATAAAC AAATTAATGA TTTTGAATAG TGACCAATAG GTCTCTTTTA TACTCTATAT TTTTCTCTTG AGTGAAAAAA AATGTTTCAA CCTCCATATG TAAATTCCAA ACACAAACTA AAGCAATGTA GAATAGCTTC TTTATTCCCT GGAGTAGGTT CTAGAGAAGT CCTAAAGGAT TGGTCCTAAA TTAATTATGC TTATTATGCT AGCGATATTT CCTTTCAAAA TTCTCCTTTA ATGAATGCTT TTTAATTTTT ACAAAAGCAT TAACCATAGA ATGTGATTCT TGTCTTTCAC

TGACTCATTA GTGACAAATA TTTGTTGAGT ACCTACCAAC TCCTAAGTAT TGCTACCAAC TCCTAAATAC TGTGTTGGGC ATTCAGAATA GAATGTAGAA CTAGACAGGG TCCCTGACTT CTTGGAGCAC AGAGCAGTAT GGGAAGAGGA CATTAAATAA AGAATTACAT AAGTAATTAA TTTAAATTAT ACATGTTTTG AAGAAGTTTT TTTTTGACAA CTATAATTAA CACTAGAACT GGGAAGTTTC TATAAGGTAA GAGAGGACAA AATAGACACT CTCCTAAGCT AAAATTCCCA AGAAAGACTG TTTATTTTCC CCTAACTAAC TAGAACTAGC AACAGAAGAT CTGAAAGGAA TTCTGGCTTT CAAGTGTTCC ATGTATGGAC TCATCAGGGA GGTCCGAGAG GCTTTGTGGC CCCAGACTGA CTTTTCAGGA GGGGAAAGGA TTTATCAATA CACAAGACAG GCTCTAAGCA TTATTTTGTG CCCTTTAAAA ATCCACTTTA TGAGCCAAAA AGTGAGTTAA TGATAATTCA TAGTTTCTGA

CACATGCTCT ATGCGTGGCT CTCTTTTCTC TATTCATTCT CTCTCTCTTC ATTTATTGTT AAATAAATAA TGTAATGAAT GTTCTTCAGA GTGGCTGCTC CTTCAGGCCT CTGCTGAGGT GGTGATGGAG GGCCAGCCCC TCTTCCTCAG GTGCCATGGT TGGAGGAACT GGGATGTGTA CAAGGTGATC TATTATAAGG ATGGTGAAGC TCTCAAGTAC TGGTATGAGA ACCACAACAT CTCCATTACA AATGCCACAG TTGAAGACAG TGGAACCTAC TACTGTACGG GCAAAGTGTG GCAGCTGGAC TATGAGTCTG AGCCCCTCAA CATTACTGTA ATAAAAGGTG AGTTGGTAAA GGAAAGGAAA AGCATCCATA GCAGGGGAAG GAAGAGAGAA CTTCTGAGCC TGAGCAGTTG CAGCTTGTAG AAGGGGGGCA CCTGTGATAC ACTGGAAAGC CTACCAGACT TGCAATGAGG AGACCTGGGT GATAGTATAT ATCTCAATCT CTGTTTCAAA GCCTTGACTT GTTAAATGGT

GATAGTAATA CCTGCTTGCA CTATGAAATT TTTATGAAGA TTAATGTGGT AATATTTGTG AAATGACTTT GTAAACTGTT AAGCACTACC CAAGCATAAC AGATTGTGAT TACTATTTTG ATCTCAAAGT CATCTGTTGC TCCTGGGGGA ACACTTATAT TTATCAAATT GAAAAAAAGT TTCAAAGTTG AATGAAGAAA GGATATAAAG AGCTTGAGGA GCCCATTCCA GCTTAGGAGG GCTGGGAAAG GAAAOCAGCA AGTCAGTAAG CTGTGTGCCT GTGTATTGAG GGAGGAGGGA ATGGACTTGA TATGGAGAGG GTAGGGAGGT GGACTGCCTC TATGGCCTGT AAGAAAAACT GCTCTCTCCA AACTCTTTAT AAGAGAGGGA GCCTGTGAAG TATTCACTTT TGAAGGAGAA AGTTAGACTT TTCCTTCACA CACTTTGTAC ATAATAATGT TTAAAAAAGC ATGAGGTCAA AATACATAAT TAAGTCCTAG CAGTTCTCTG TTAACTAATT TGAGACTGAA GTGCTATGTA

CTTGTCTCTA GGCTTCCAGT ATCTTCATCT GTAAAACAGA ATATTTGGTC TAGATTCCAT TAGAATCATT TGATAACTTA AAAAATATAT TGATGCTCAT GTCTCATTTC TTGAGATTCT GATTTAATTG GTTTGGGGTG CAGCCTGGGT ATACGTATTT TTCATAGGTC TTTCACATAA TGGTAATGGG TAGCCAATAT TGAGAATCAC TTGTCTAGGT GATCTTTAAA TGATTTCTGG ATGTAATATT CTGAGGCTCT ATAATTTGAG ACTAATCACA AAAATCGGTA CAGTTTATAA ACAGACTAAC AGAACCACAA AATAATAGAA TTGGAAGGCA ATTTAACTAG TGCAATTTCT TCATTTTGCC TAACAGGCAT GTAAGAAATG ATGATTGATT GAGTAATAGG CATTGATGAC CCCTGTCCTC ACTTTGTCCC CTTTCCACCC CTTAATTATA TGTGAATTCT GGTCTTGTCA TTTCGAATAA GGGGTTTATC TTTCCTATTG TCTTCCCCTC TGGGCACGGC ACACTGGCTA CTGGAGTTAA

GAGGAAATGC TTAGGACTCC CTGTGGCTCC AGGGAGCACC AACAGAGCAA CTCAACCTAG TGTTAATCTG AGTGTTTTCT CTGTGCTTCT GGATGCCACA TCACGCTAAA AATGAAGGAC AAAGCTTGGT CTTTCTCTTA GGGAGGATGA AACTCTGAAC CTCATTTTTC AGTTCCCAAG ATGAATTATG TTTCTCATTG CATCTGTGTT CCACTACAGC TCCGCGTGAG AAGTACTGGC TACAATTTTT TATCCCATTG TTGGTGGTGA TTCTGTTTGC TGTGGACACA GGATTATTTA TCTCAACTCA GCAGCAGGTC ACATTTCTCT TGAAGATTAA GAGAACCAGG AAAGGCTTCA GACTTCTGAA CCCACATCCT AAGCCAAACC CCAAAAACAA CTGATATAAT TACTCAAGAA ATATTTGCAA CATTAGTTTT TTTCCAGCAT CAGCAATTGC TACTCAATTG TCAAACACAG CTTGCAATAT ACATAGAAAC GTCTGTGCTC AAGGATTTAT AGAAATGCTT CATTAAACTG AGTGAAACTG

GTTAAGTGGC ATGTAATAGT AAGTGCTCAA TTAACATTGG TTGAATAAAT GAGAGAATGA ATAGATTCAT TTATTAGCAT TTGTAAAAGA GATGTTCAAT TTCAATAAAA TAAATATAAA ACCATGTAAC AGAATGCTTC TGAGTATTCA AGGCTTGCTA GTTTGTTTGT TTGTTTTCTA CTAAAGGCAA GGACCATGAA GTTCTAGATT GGAAATGTCC TCTCTTGACT ATTGCAAGTG CGATCTAGGA ATGAAAAGAC ATAGGAGGAT GCCAGTGAGG TGGATCATTT TTATGCTTCT TCTTCAGCTT ACTAAATATG AACTTTCAGT TCTTGGCAGA ATCAGGGACA GTCTCAAGAC ATAGGACTCT CAGGATGAAG TAGAGTCCAG GATTCCTCTG TGATTGTTTT GCCCCTCCCA AATTTATATC TTGAACTTAT GTCTTGTATC TTTATACAGC ACCTGAACCA AGCATTTTGG AGAAATTCCA GCTAATAATA ATAACCAAAA CCTTCGGCTC TGAAAACAGT CCAGGACTGA ATAAGATCTT

GGGCAAAAGA ACTAGACAGT TTTGGTTTAT TTTCCCTTTC ATTTTATGTC TTCATCATAG TCATTGGAGG CTCATTCTTC TTGTCATGGA GTAAATGGGA TTAAAGTTC-3* (FRAG NO J(SEQ ID NO 11870)

5'-TACTAAGAGT CTCCAGCATC CTCCACCTGT CTACCACCGA GCATGGGCCT ATATTTGAAG CCTTAGATCT CTCCAGCACA GTAAGCACCA GGAGTCCATG AAGAAGATGG CTCCTGCCAT GGAATCCCCT ACTCTACTGT GTGTAGCCTT ACTGTTCTTC GCTCCAGATG GCGTGTTAGC AGTCCCTCAG AAACCTAAGG TCTCCTTGAA CCCTCCATGG AATAGAATAT TTAAAGGAGA GAATGTGACT CTTACATGTA ATGGGAACAA TTTCTTTGAA GTCAGTTCCA CCAAATGGTT CCACAATGGC AGCCTTTCAG

AAGAGACAAA TTCAAGTTTG AATATTGTGA ATGCCAAATT TGAAGACAGT GGAGAATACA AATGTCAGCA CCAACAAGTT AATGAGAGTG AACCTGTGTA CCTGGAAGTC TTCAGTGACT GGCTGCTCCT TCAGGCCTCT GCTGAGGTGG TGATGGAGGG CCAGCCCCTC TTCCTCAGGT GCCATGGTTG GAGGAACTGG GATGTGTACA AGGTGATCTA TTATAAGGAT GGTGAAGCTC TCAAGTACTG GTATGAGAAC CACAACATCT CCATTACAAA TGCCACAGTT GAAGACAGTG GAACCTACTA CTGTACGGGC AAAGTGTGGC AGCTGGACTA TGAGTCTGAG CCCCTCAACA TTACTGTAAT AAAAGCTCCG CGTGAGAAGT ACTGGCTACA ATTTTTTATC CCATTGTTGG TGGTGATTCT GTTTGCTGTG GACACAGGAT TATTTATCTC AACTCAGCAG CAGGTCACAT TTCTCTTGAA GATTAAGAGA ACCAGGAAAG GCTTCAGACT TCTGAACCCA CATCCTAAGC CAAACCCCAA

AAACAACTGA TATAATTACT CAAGAAATAT TTGCAACATT AGTTTTTTTC CAGCATCAGC AATTGCTACT CAATTGTCAA ACACAGCTTG CAATATACAT AGAAACGTCT GTGCTCAAGG ATTTATAGAA ATGCTTCATT AAACTGAGTG AAACTGGTTA AGTGGCATGT AATAGTAAGT GCTCAATTAA CATTGGTTGA ATAAATGAGA GAATGAATAG ATTCATTTAT TAGCATTTGT AAAAGAGATG TTCAATTTCA ATAAAATAAA TATAAAACCA TGTAACAGAA TGCTTCTGAG TAAAAAAAAA AAAAAAAAAA AAAAAAAA-3' (FRAG NO J(SEQ DDNO 11871) 5'-TCTCAATATA ATAATATTCT TTATTCCTGG ACAGCTCGGT TAATGAAAAA ATGGACACAG AAAGTAATAG GAGAGCAAAT CTTGCTCTCC CACAGGAGCC

TTCCAGTGTG CCTGCATTTG AAGTCTTGGA AATATCTCCC CAGGAAGTAT CTTCAGGCAG ACTATTGAAG TCGGCCTCAT CCCCACCACT GCATACATGG CTGACAGTTT TGAAAAAAGA GCAGGAGTTC CTGGGGGTAA CACAAATTCT GACTGCTATG ATATGCCTTT GTTTTGGAAC AGTTGTCTGC TCTGTACTTG ATATTTCACA CATTGAGGGA GACATTTTTT CATCATTTAA AGCAGGTTAT CCATTCTGGG GAGCCATATT TTTTTCTATT TCTGGAATGT TGTCAATTAT ATCTGAAAGG AGAAATGCAA CATATCTGGT GAGAGGAAGC CTGGGAGCAA ACACTGCCAG CAGCATAGCT GGGGGAACGG GAATTACCAT CCTGATCATC AACCTGAAGA AGAGCTTGGC CTATATCCAC ATCCACAGTT GCCAGAAATT TTTTGAGACC AAGTGCTTTA TGGCTTCCTT TTCCACTGAA ATTGTAGTGA TGATGCTGTT TCTCACCATT CTGGGACTTG GTAGTGCTGT GTCACTCACA

ATCTGTGGAG CTGGGGAAGA ACTCAAAGGA AACAAGGTTC CAGAGGATCG TGTTTATGAA GAATTAAACA TATATTCAGC TACTTACAGT GAGTTGGAAG ACCCAGGGGA AATGTCTCCT CCCATTGATT TATAAGAATC ACGTGTCCAG AACACTCTGA TTCACAGCCA AGGATCCAGA AGGCCAAGGT CTTGTTAAGG GGCTACTGGA AAAATTTCTA TTCTCTCCAC AGCCTGCTGG TTTT-3'(FRAG NO J(SEQ ID NO 11872) 5'-AAGCTTTTCA AAGGTGCAAT TGGATAACTT CTGCCATGAG AAATGGCTGA ATTGGGACAC AAGTGGGGAC AATTCCAGAA GAAGGGCACA TCTCTTTCTT TTCTGCAGTT CTTTCTCACC TTCTCAACTC CTACTAAAAT GTCTCATTTT CAGGTTCTGT AAATCCTGCT AGTCTCAGGC AAAATTATGC TCCAGGAGTC TCAAATTTTC

TTATTTCATA TTAGTCTTTA TTTAGTAGAC TTCTCAATTT TTCTATTCAT CACAAGTAAA AGCCTGTTGA TCTTAATCAG CCAAGAAACT TATCTGTCTG GCAAATGACT TATGTATAAA GAGAATCATC AATGTCATGA GGTAACCCAT TTCAACTGCC TATTCAGAGC ATGCAGTAAG AGGAAATCCA CCAAGTCTCA ATATAATAAT ATTCTTTATT CCTGGACAGC TCGGTTAATG AAAAAATGGA CACAGAAAGT AATAGGAGAG CAAATCTTGC TCTCCCACAG GAGCCTTCCA GGTAGGTACA AGGTATTATT TTTTTCTACC CTCAGTCACT TGTGGCAGGG GAAGTCATAG TCACGGTGCT TAGGAGATGA AACTTTATTG ATTTAGGCAT GGATCCATCT AGTTTAATTA ATATATTGGG TATGAGGAAG CTACTTGCTG TACTTTCCAT GTGGTTCTCT CTCCCTGGAG AGGAACATTT TTACTCAGCT TGCAAACTGG AAATAGATTT TCTCACATTA GAAGCTCATT TTCTGGGTAT

GAGACAGGAG AGTTCATACT GTGTATGTAG ATCTCTGGCT TCTGGGTCTG ACATGTGCTG AGGGACACAT ATCCTTCACA CATGCTTTTA TAAATACTTG ATAAAGTAAC CTGCTTCTTG ATTGGTCTTT ATAATCCATA AGCTGTGGGA TGCTTCTCTG AAGATGAAAA TAGTAATAGA GTCCCATCTA GCTATTCAAA GCCATTCCTT CATTGTATTC TGTGCACATG AAGTTGGGGT TTGTTACTGA CAAAATATAT TCAGATACAT TTCTATGTTA AAAGGATTGT GAGATGCATA GGTAAATGTG TTTATTTTCA GTTTTACTTG TCAACATAGA TGAATGAGAA AGAACTTGAA AGTAACACTG GATTAAGAAT AGGAAAATTT GGCATGGATT TTGCTCCATT TTGTCCCATC TAATCACTTG GATAGTGTTC AGGTGTTCTT GGTCAGTTAC TTGGATGCTC TGAGCTTTAG TTTCTTGGTG ATTACAATGA AGATTTGAAT TACAGGATGG CTTTGAAAAA ATAAACAAAA CTCCCCTTTC

TGTCTGTCGA GAATGTTGCA CAGGGAGTTA CAGAATGTTC TCATGACTGA ATTGCTTTTA AATTTCACAG TGTGCCTGCA TTTGAAGTCT TGGAAATATC TCCCCAGGAA GTATCTTCAG GCAGACTATT GAAGTCGGCC TCATCCCCAC CACTGCATAC ATGGCTGACA GTTTTGAAAA AAGAGCAGGA GTTCCTGGGG GTGAGTGAGC CTCCTCCAAC TTTGACTAGA GTAAGGGTTG GGTCTAGAAA AGAATATTGA GTTGCATCAA CTGTTTTCCC ACTTGGATTC ATGAGAGGTG TTAGGTCCTT TAAAAAACAT GGTAGATAAA GAGTTGACAC TAACTGGGTC CTTTTGGGAA GAGCCAGAAG CATTTCCTCA TAAAGACTTT AAATTGCTAG GACGAGAATG GCCAACAGGA GTGAAGGATT CATAACTTTA TCTTTACTTA GATGTAAAGA ACAATTACTG ATGTTCAACA TGACTACATA CATAAAGGCG CATGGAGAAA AGTATTGGCC TTCCATGCAT TAGGTAGTGC TTGTATCAAT

TCTTATAGTG GCTAGGGTAT CCTGGAAAAT CTTACGTGTG GATCATTTCT CAGGACAGTC TAGGACACTA ACGCAGTTTC TCATGTTTGG CTTCTATTAT TAAAAAATGA TACAATCTCG GGAAAATTTT TTTGATTTTC ATGAAATTCA TGTGTTTTTC TATAGGTAAC ACAAATTCTG ACTGCTATGA TATGCCTTTG TTTTGGAACA GTTGTCTGCT CTGTACTTGA TATTTCACAC ATTGAGGGAG ACATTTTTTC ATCATTTAAA GCAGGTTATC CATTCTGGGG AGCCATATTT GTGAGTATAT ATCTATAATT GTTTCTGAAA TAACACTGAA CATAGGTTTT TCTCTTTCTC AGATCTAACC AGTTGTTTAT TCCCAGTATT AAGATGATAT TTATAATTCT TAATTATAAA TATATGTGAG CATATATAAC ATAGATATGC TCATTAACAA CAACAAAAGA TTCTTTTTAC AATTAACGGT GGGTTAAACA TTTAGCCCAC AGTTTTATCC CATGAGAAAC CTGAATCTAA TACAAGTTAA

ATGACTTGCC TAAGGGCCAC TTGACTAATA GTAATTGAAC CTAAACTTTC AGAATCCAAC TCCAGGAACA TACTTCTAGC ACTATTCATC AATAAAGTTA TATGATAAAT ACATACAACT TTATCTGTCA ACTAAAAATA ACAACAGAGG CTGGGCATGG TGGCTCACAC CCGTAATCCC AGCACTTTGG GAGGCTGAGG CAGGTGGATC ACCTGAGGTC AGGAGTTTGA GACCAGCCTG ACCAACATGG TGAAACCTCA TCTCTACTAA ATATAAAAAA TTAGCTGAGT GTGATAGTGC ATACCTGTAA TCCAGCTACT TAAGAGGCTG AGGCAGGAGG CTTGTTTGAA CCTGGAAGGC AGAGGTTGCA GTGAGCTGAG ATTGTGCCAT TGCACTCCAG CCTGGGCAAT AAGTGCGAAC TCTGTCTCAA AATAATAATA ATAATAATAG AAAATAAAGT TGTCTTCATG AAAAATGAGG AAAGAGATTG CTGGGGTGAG AAACATTAAG ATCAATGGGC ATATGGTGAC CTTCTATGCC CTAGAAACTC

TTTTANGGTA TTTTCTCCTG GTATCTCTTT TACNCATCGT TCTATCTGGA AAAATAGGTG GATGAGTGAG ATAATAACGG TATATACTTT TTAAAGGTCT AATTGACATA TATAAATTGC AAGTATTTCA GATGTCAATT TGCTAACCTT GACACACATA GACACACATG AAAACATCAC CACATTAATA CAATGTATGT ATCCATCATT CCAAAAGCTT CCCTGTGTAT CTTTGTAACT CTTTCTTCCT CCCTCCACTC CTTGTCCTCT CGTTCCCAAG AAAACATTGA TCTGCTTCCT GTGAATATAA ATTAACTTAC ATTTTTTAGA GCTTTATATA AGTATGTTCT CTTTACTGTT TGTCTTCCTT CGCTGCACAG TTATTTTGAG ATTCTTCAAG TTTTTTCTTT ATATCGATAC TTCATTCACA AGAATATATT TTAATTCTAG ACTATGTCAC ATTGACTTTG TCGTCTGCTA AATCCTTAGT GCTCAGATGA CTTGTTCAGG ACTCTCCTTG AACCTGTACC TCTGTTAKAT TGAAACTTGT

CTCTACTGTC TTTTTATTTC AAACACAGCT TATTAGGTGT CTCTCAACCC ATCAAACNCA CAATCTGAGT CTTTAGGAGA TTGCTTTGAA TTTGTGCTAT TGACTTATAT NTATATNAAA TNTGTAAATG TTTGGTAAAA ATATCATCAT GTACNTTTTC ATAATTACGC TATNTNCACA TGATATATGT CAGACTCTGG AAATATGCAT GCCACAGACA CGTGTTTCTT GCCTAAAGGG GCTGATGGAA GACNCACATA CNAATAGACG ATTGCAGTAG AATGAGAGTG GTGGTCTAAN CAGTACATGT CCTGATGTTG CTCGGACAGT TACTACNCCA AGAGTACCCC CTGCATTGTC AGGGTTAGCA TCTCCTGGAA GCCTCATGTA AATGAAGAAT TTCATGCTCC ATCCAGGACC TAATGAATAA GAATCTGCAT TTTAGCAAGA CCCTCATATG ATTCATATAC ACTTTTTTTT TTTTTTTTTA GATGGAGTCT CACTCTTGTC GCCCAGGCTG GAGTGCAATG GCATGATCTT GGCTCACTGC

AACCTCTGCC TCCCGGGTTC AAGTGATTCT CCTGTCTCAG CCTCCCTAGT AGCTGGGACT ACAGGTGCAT GCCACAGTGG CTGGCTAATT TTTGTATTTT TAGTAGAGAC AGGGTTTCAC CATTTTGGTC AGGCTGGTCT TGAACTCATG ACCTCCGGTG ATTCCCCCGC CTCGGCTTCC CAAAGTGCTG GGATTACAGA CATGAGCCAC CACACCCGCC TTATTCGTAT ACNCATTTAA TTCTGAGAAG CACTCTATAG AAAATAAGAA TAAGAAAATA TTGGGCTCAC AGGTGACATT AATAAGTAAC TTTATCGAGT ACCCCAAATT TTACCTATGT TTGGAAGATG GGGTTAAAAG GACACATTGA AAACAAGAAC TCATTGTGGC TTTTTTTTCC TCCTTTTTGA ACAGTTTTCT ATTTCTGGAA TGTTGTCAAT ' — ^

TATATCTGAA AGGAGAAATG CAACATATCT GGTGAGTTGC CCGTTTCTGT CTTTGTCCAT CCTTGAAAAG ATAAGAAGAA CAGAGTTTTA AGAGTCTTAA GGGAAACACA TCTTTGTCTC CTATATTACT TGTGAATGTG GATATATGAT TTTGTTTCAA TCTATTTTGT GTCCTAAGGC TTTTTGCAAC AGAAGTTGGA TATATCATTA GAAACATAAA TTGTACCATT TAACATACAT GAAGTTTATG TTTACCTTGA CGTTCTTCTA AAAAGTGTCC TACACCGGCA TTGTCCTTGT AGGCATATTC ACATGATCAA ATAAAATAAT TAGTTTTCAA TTAAGGAGAA TATTTGAGGA AAGACCGTAC GTGTTCATGT GGTTCCTGAA GGCAGTCCAG TGAGAAAGTA ATATATGCTT CATTAAACAA TGCGGACATT TTCAGGGTTT CCCTTTTTAA CCAAAATTTG GAAGCAATGT GGAATTTACT GGATGCATCC AGCCCTGAAA TGAAGATAGG TTTATTGAAT GTGCCAGCAA GTGCAGGCCC

AGGTCTGAGT GTTCTTCATT ATTATCAGGT GAGAGGAAGC CTGGGAGCAA ACACTGCCAG CAGCATAGCT GGGGGAACGG GAATTACCAT CCTGATCATC AACCTGAAGA AGAGCTTGGC CTATATCCAC ATCCACAGTT GCCAGAAATT TTTTGAGACC AAGTGCTTTA TGGCTTCCTT TTCCACTGTA TGTATTTTTT TTTGTGTGGG AAGACTAAGA TTCTGGGTCC TAATGTAAGT AAGAAGCCCT CTTCTCCTGT TCCATGAACA CCATCCTTTT CTGTAACTTC TATTACACAG TATAGTGGTT CTGTAAGTTC ACACAGCCCA GGGAGATGCT GGCTGCCCAC TCCCCTCAAC CCAGGCAAAT TCCTCGGGGT TAAAGTTATC TACTGCAAGT GACGATCTCT GGGTTTTTCT GTGCCTGTGT TTGTGTGTGT GTGTGTGTGT GTGTGTGTGT GTATGTGTCA CTTTAAAAGG ACTGGTCAGA TGGTAGGGAG ATGAAAACAG GAGATGCTAT AAGAAAATAA ACTTTTGGGG CGAATACCAA

TGTGACTCTT TTTGTTTGTC ATTTGTTGCT GTTCAATAGG AAATTGTAGT GATGATGCTG TTTCTCACCA TTCTGGGACT TGGTAGTGCT GTGTCACTCA CAATCTGTGG AGCTGGGGAA GAACTCAAAG GAAACAAGGT AGATAGAAGC CCGATATAAA ATCTTGAATG ACAGGTTAAC GAATTGGAGC TTTATTCCTT AAAATATGGC CTGGGTTTTC TGAAACATTT CTTCCAGAAA ATAGTTTCTC CAAGTTTTAT TACTTTGGTT TACAAATCTC ACATTTAAAT CACATTTTAT ACCATAAGTA GCACACATTT CATAATATTC CTCTGAATGA GGGTTGGGAT AATAGGACTG ATATGTTAGA AATGCCTTAA AGTGTGTGGA GCATGAGAGA TGGATGTACA GAAGGCTTGT GAGGAAACCA CCCAGGTATC TGGCCTTGTT TTCTGCCCCA GAACTAGCCG CCTATTCCTG TTTCTGTTTT ATTCCTTTGT TTCTTGACTT TTCCTTTCCA ACTTGCTCTA AAACCTCAGT TTTCTTTCCT

TTCTGATTCA TGACTACCAA ATGTTTTCAC TTGCCTCACC CGTCCATTAC ACCTTTGATA AGAACCACCA GACCTTGTGC TCATGTACTT GCCCATGTCT GATGGAAGAA ACATACTCTC TCCATCTGTC CACTTTCCTG AGGCATTCAA GTCTAGCCAC CTTTTAAAAT CACTCTCCTC CAGGCTGGGC ACGGTGTCAC GCCTGTAATC TCAGCACTTT GTGAGGCTGA GGAGGGCGGA TCACTTGAAG TCAGGAGTTC AAAACCAGCC TGGCCAAATG GCAAAACCAA ATCTTCTTCA ATTATAACCA AATCTTAAAC CAAATCTCTA CTAAAAAATA CAACAAAACA AAACAACAAC AACAAAAACA GAAAAGGAAA CATTAGCCCA GCGTGGTGGC AGGTACCTGA GGTTCCAGAT ACTTGGGAGG CTGAAGCAGG AGAATCGCTT GAGCCCAAGA GATGGAGGTT GCAGTGAGCC GAGATCATGC CACTGCACCA CAGCCAGGGT GACAGAGCCA TACTTCCCAG

CACATTGGGA GGCCAAAGCT GAAGAATAAT TTGAGGTGAG GATTTGGAGA CCAGCCTGGC CAACATGGTG AAACTCCGTC TGTACTAAAA ATATAAAACT TAGTGGGGCA TGGGGGCACA CACCTGTAAT TTCAGCTACT TAGGAGGCTG AGGCAGGAGA ATTGCTTGAA CCCGGGAGGC GGAAGTTGCA GTGAGCCAAG ATCGTGGCCA CTGCACTCCA GCCTGGGTGA CATAGTGAGA TTCTGTCTCA AAAAAAATAA AAGAAATTTA AAAAATCACT CTCTTCCAAA GATAGATAAA TAAGACAGCA GATATACTAA GGAATAACCT CACCAACTTG TCATTGACTG ACATGATTTC TTTTGGCCCA CTTGGCCAGC TAGTCTGGTT TGGTTTTCTG GAAATGAAAG AAATAATCAG AGTTTAATGA CAGAGAGCGT GAGACCCAGA AAGACAAAAG TAGATGAGGT AAGTCTCTTG AGCGAGACTT CTAGGGATGG GAAATTTGTG GTGATTGATA TGAAATGATT TTTCCCTTAT CAGGTTCCAG

AGGATCGTGT TTATGAAGAA TTAAACATAT ATTCAGCTAC TTACAGTGAG TTGGAAGACC CAGGGGAAAT GTCTCCTCCC ATTGATTTAT AAGAATCACG TGTCCAGAAC ACTCTGATTC ACAGCCAAGG ATCCAGAAGG CCAAGGTTTT GTTAAGGGGC TACTGGAAAA ATTTCTATTC TCTCCACAGC CTGCTGGTTT TACATTAGAT TTATTCGCCT GATAAGAATA TTTTGTTTCT GCTGCTTCTG TCCACCTTAA TATGCTCCTT CTATTTGTAG ATATGATAGA CTCCTATTTT TCTTGTTTTA TATTATGACC ACACACATCT CTGCTGGAAA GTCAACATGT AGTAAGCAAG ATTTAACTGT TTGATTATAA CTGTGCAAAT ACAGAAAAAA AGAAGGCTGG CTGAAAGTTG AGTTAAACTT TGACAGTTTG ATAATATTTG GTTCTTAGGG χχχχχχ_ττχχ XTXXAGCATT CTTAATAGTT ACAGTTGGGC ATGATTTGTA CCATCCACCC ATACCCACAC AGTCACAGTC ACACACACAT

ATGTATTACT TACACTATAT ATAACTTCCT ATGCAAATAT TTTACCACCA GTCAATAATA CATTTTTGCC AAGACATGAA GTTTTATAAA GATCTGTATA ATTGCCTGAA TCACCAGCAC ATTCACTGAC ATGATATTAT TTGCAGATTG ACAAGTAGGA AGTGGGGAAC TTTTATTAAG TTACTCGTTG TCTGGGGAGG TAAATAGGTT AAAAACAGGG AAATTATAAG TGCAGAGATT AACATTTCAC AAATGTTTAG TGAAACATTT GTGAAAAAAG AAGACTAAAT TAAGACCTGA GCTGAAATAA AGTGACGTGG AAATGGAAAT AATGGTTATA TCTAAAACAT GTAGAAAAAG AGTAACTGGT AGATTTTGTT AACAAATTAA AGAATAAAGT TAGACAAGCA ACTGGTTGAC TAATACATTA AGCGTTTGAG TCTAAGATGA AAGGAGAACA CTGGTTATGT TGATAGAATG ATAAAAAGGG TCGGGCGCGG AGGCTCACGC CTGTAATCCC AGCCCTTTGG GAGGCCGAGG

TGGGCAGATC ACGAAGTCAG TAGTTTGAGA CCAGCCTGGC CAACATAGTG AAACCCCGTC TCTACTAAAA ATACAAAAAA AAAATTAGCT GGGTGTGGTG GCAGTCACCT GTAGTCCCAG CTACTTGGGA GGATGAGGCA GGAGAATCGC TTGAACCTGG GAGGCGGAGG TTGCAGTGAG CCGAGATCGC ACCAGTGCAC TCCAGCCTTG GTGACAATGG GAGACTCCAT CTCAAAAAAA AAAAAAAAAA AAAAAAGATA AAAAGTCAGA AATCTGAAAA GTGGAGGAAG AGTACAAATA GACCTAAATT AAGTCTCATT TTTTGGCTTT GATTTTGGGG AGACAAAGGG AAATGCAGCC ATAGAGGGCC TGATGACATC CAATACATGA GTTCTGGTAA AGATAAAATT TGATACACGG TTTGGTGTCA TTATAAGAGA AATCATTATT AAATGAAGCA AGTTAACACT CTAAGAGAAT TATTTTGAGA TAGAAGTGAA GCTAAGCTAA ACTTCACATG CCTATAATTG

GAGGGAAAAA CTAAGGATAA AATCTAGCCT AGAAGATACA ATAATTAGTC ATAAACATGC ATTGTGAAAG TGTAGAGAGC AGGTAGCCCA AAATAGAGAA AGATTAGATA AAGAGAAAAT AAGTATCCAT CAGAGACAGT ATCTCTAGGC TTGGGCAAGA GAAAAGTCCA CAGTGATAAG CAACTCCACC TAAGGCATGA ATATGCGGCA GAGAAAACAG CAATAGTGAA TGAATGCAAA AGGTGCTGAG CAAATTCCAC ACATGAGTAT TGTGCATGAG TAAATGAATA AAACATTTGC AAAGACCTTT AGAGAAAGAG AATGGGAGCA TATGTGCGAA ATAAGATAGT TGATTATGAA TAGAAGGTAG TGAAGAAAAG CAAGCTAAGA AAAAATTCTG TTTATAAAAG AAGGAAAAGA TAGTTTATGT TTTTAGCCTA AGTATAAGAG TCCTACAGAT GGACTGAAAA AAATCAGTCT GAGAGTATTA GTCACAATTA ATGAAATAAT TACATTTTAT

GTATTGAGGA TGCCAAGATT AAAAGGTGAC AGGTAGATGT TAATTTCCCT AGATTGTGAA AGTGATCACG ACAATCACAC AACAAATAAT TAAGTGACTT GGTATGCTTT ATTTAATTGT AGGGCCTGAG GTTTTCCATT CTCATTTTTC TAAAATACAA TTTTGTTTCT CCAAATTTGA CAGCAGAATA AAAACCCTAC CCTTTCACTG TGTATCATGC TAAGCTGCAT CTCTACTCTT GATCATCTGT AGGTATTAAT CACATCACTT CCATGGCATG GATGTTCACA TACAGACTCT TAACCCTGGT TTACCAGGAC CTCTAGGAGT GGATCCAATC TATATCTTTA CAGTTGTATA GTATATGATA TCTCTTTTAT TTCACTCAAT TTATATTTTC ATCATTGACT ACATATTTCT TATACACAAC ACACAATTTA TGAATTTTTT CTCAAGATCA TTCTGAGAGT TGCCCCACCC TACCTGCCTT TTATAGTACG CCCACCTCAG GCAGACACAG AGCACAATGC TGGGGTTCTC TTCACACTAT

CACTGCCCCA AATTGTCTTT CTAAATTTCA ACTTCAATGT CATCTTCTCC ATGAAGACCA CTGAATGAAC ACCTTTTCAT CCAGCCTTAA TTTCTTGCTC CATAACTACT CTATCCCACG ATGCAGTATT GTATCATTAA TTATTAGTGT GCTTGTGACC TCCTTATGTA TTCTCAATTA CCTGTATTTG TGCAATAAAT TGGAATAATG TAACTTGATT TCTTATCTGT GTTTGTGTTG GCATGCAAGA TTTAGGTACT TATCAAGATA ATGGGGAATT AAGGCATCAA TAAAATGATG CCAAAGACCA AGAGCAGTTT CTGAAGTCCT CCTTTTCATC AGCTCTTTAT CAAACAGAAC ACTCTATAAA CAACCCATAG CCAGAAAACA GGATGTAGGA ACAATCACCA GCACACTCTA TAAACAACCC ATAGCCAGAA AACAGAATGT AAGGACAATC ACCAGCCATC TTTTGTCAAT AATTGATGGA ATAGAGTTGA AAGGAACTGG AGCATGAGTC ATATTTGACC AGTCAGTCCT CACTCTTATT

TACTTGCTAT GTAAACTTGA GAAAGCTTTT TTCTCTTTGT GAACCTCAGG TTTTACATCT GAAAATGAGA AATTTGGAAC AAAAGATTCC TAACTGGTCT TTCTGTTCCC ATATTCTGTG ATTTTTCAAT ATTTAGGATT TTTGGTAATC ACAATTACTT AGTTTGTGGT TGAGATAGCA ACACGAATCA GAACTATTTG GTGGACATAT TTTCAAAGGA GTAGCTCTCC ACTTTGGGTA AAGAAGTGAT GCNGGTCGTG GTGGCTCACG CCTGTAATCC CAGCACTTTA GGGAGGCCAA GGCGGGTGGA TCACGAGGTC AGGAGATCGA GACCATCCTG GCTAACACGG TGAAACCCCG TCTCTACTAA AAAATACAAA AAATTAGCCA GGCGTGGTGG CGGGCGCCTG TAGTCCCACG TACTCGGGAG GCTGAGGCAG GAGAATGGCA TGAACCAGGG AGGCGGAGCT TGCCGTGAGC CGAGATAGCG CCACTGCAGT CCCTCCTGGG CAAAAGAGCA AGACTGCGTC TCAAAAAAAA

AAAAAAAAAA AAAAAAAGAA GTGTGTGGAG TAGCAGGACA CCTGCAACAA TAATATTTTT CTAAATCCCT CTGAAAAATG CTAATCAAAG GGTTTTTTTC CTAAAAATTG TCTTAGAAAT AAAATTTCCC CTTTGGGAGA CCGAGGCTGG CAGATCACGA GGTCAGGAGA TAGAGACCAC GGTGAAACCC CGTCTCTACT AAAAATACTA AAAATTAGCC GGGGNGTGGT GGTGGGTACA CCTGTAGTCC CAGCTACTTG GAGGCTGAGG CTGGAGAATC ACGTGAAC-3' (FRAG NO _)(SEQ DD NO 11873)

Human Histidine Decarboxylase Nucleic Acid and Antisense Oligonucleotide Fragments 5'-TCT CCC TTG GGC TCT GGC TCC TTC TC TCT CTC TCC CTC TCT CTC TGT CGC CTC CGC CCT GGC TGC TGG GGT GGT GGT GC TTT TGT TCT TCC TTG CTG CC

GCC CCG CTG CTT GTC T TC CTC G CTC TGT CCC TCT CTC TCT GTB CTC CTC BGG CTC CBT CBT CTC CCT TGG GC-3'(FRAG NO 1700) (SEQ DD NO 11082)

5'-GGC TCT GGC (FRAG NO 1701) (SEQ ED NO 11083)

5'-CCC TTG G (FRAG NO 1702) (SEQ ID NO 11084)

5'- T TGT TCT TCC (FRAG NO 1703) (SEQ DDNO 11085) 5'- TCT CCC TTG GGC TCT GGC TCC TTC TC-3' (FRAG NO 1024) (SEQ DD O 10403)

5'- TCT CTC TCC CTC TCT CTC TGT -3' (FRAG NO 1025) (SEQ ID NO 10404)

5'- CGC CTC CGC CCT GGC TGC TGG GGT GGT GGT GC-3' (FRAG NO 1026) (SEQ DD NO 10405)

5'- TTT TGT TCT TCC TTG CTG CC-3' (FRAG NO 1027) (SEQ ED NO 10406)

5'- GCC CCG CTG CTT GTC T TC CTC G-3' (FRAG NO 1028) (SEQ ED NO 10407) 5'-CTC TGT CCC TCT CTC TCT GTB CTC CTC BGG CTC CBT CBT CTC CCT TGG GC (FRAG NO 1029)(SEQ DDNO 10408)

Human Beta Tryptase Nucleic Acid and Antisense Oligonucleotide Fragments

5'-CTT GCT CCT GGG GGC CTC CTG GTC CCT CCG GGT GTT CCC GGC GGG CCT GGC CTG GGG CBG GGG CCG CGT BGG CGC GGC TCG CCB GGB CGG GCB GCG CCB

GCB GCB GCB GBT TCB GCB TCC TGG-3' (FRAG NO 1704) (SEQ DD NO 11086)

5'- GCT CCT GGG GGC CT-3' (FRAG NO 1705) (SEQ DD NO 11087) 5'-CGT BGG CGC-3' (FRAG NO 1706) (SEQ DD NO 11088)

S'-T GGC CTG GGG-3' (FRAG NO 1707) (SEQ DD NO 11089)

5'-CTT GCT CCT GGG GGC CTC CTG-3' (FRAG NO 1030) (SEQ D NO 10409)

5'-GTC CCT CCG GGT GTT CCC GGC-3' (FRAG NO 1031) (SEQ DD NO 10410)

5'-GGG CCT GGC CTG GGG CBG GGG CCG CGT BGG CGC GGC TCG CCB GGB CGG GCB GCG CCB GCB GCB GCB GBT TCB GCB TCC TGG 3' (FRAG NO 1032) (SEQ ED NO 10411)

Human Tryptase-I Nucleic Acid and Antisense Oligonucleotide Fragments

5'-CTT GCT CCT GGG GGC CTC CTG GTC CCT CTG GCT G TT CCC GGC CCT GGB CTG GGG CBG GGG CCG CGT BGG CGC GGC TCG CCB GGB CGG GCB GCG CCB GCB

GCB GCB GGC TCB GCB TCC TGG CCB CGG BBT TCC-3' (FRAG NO 1708) (SEQ ID NO 11090)

5'-CT CCT GGG GGC CTC CTG-3' (FRAG NO 1709) (SEQ DD NO 11091) 5'-B TCC TGG CCB CGG BBT TCC -3' (FRAG NO 1710) (SEQ D NO 11092)

5'-GTC CCT C-3' (FRAG NO 1711) (SEQ DD NO 11093)

5'-CTT GCT CCT GGG GGC CTC CTG-3' (FRAG NO 1033) (SEQ DD NO 10412)

5'-GTC CCT CTG GCT GTT CCC GGC-3' (FRAG NO 1034) (SEQ D NO 10413)

5'-CCT GGB CTG GGG CBG GGG CCG CGT BGG CGC GGC TCG CCB GGB CGG GCB GCG CCB GCB GCB GCB GGC TCB GCB TCC TGG CCB CGG BBT TCC -3' (FRAG NO 1035) (SEQ DD NO 10414)

Human Prostaglandin D Synthase Nucleic Acid and Antisense Oligonucleotide Fragments 5'-GGT GTG CGG GGC CTG GTG CC CCT GGG CCT CGG GTG CTG CCT GT GCG CTG CCT TCT TCT CCT GG GTC CTC GCC GGG GCC CTT GCT GCC CTG GCT GT GCC CTG GGG GTC TGG GTT CGG CTG T CCC CBG CBG GBC CBG TCC CBT CCB CBG CGT GTG BTG BGT BGC CBT TCT CCT GCB GCC GBG-3'(FRAGN0 1712)(SEQ DD NO 11094)

5'-T TCT CCT GCB GCC GBG -3' (FRAG NO 1713) (SEQ DD NO 11095) 5'-CTT GCT GCC CTG GCT GT-3' (FRAG NO 1714) (SEQ DDNO 11096)

5'- TCT TCT CCT GG-3' (FRAG NO 1715) (SEQ DD NO 11097) 5'-GGT GTG CGG GGC CTG GTG CC-3' (FRAG NO 1036) (SEQ DD NO 10415) 5'-CCT GGG CCT CGG GTG CTG CCT GT-3' (FRAG NO 1037) (SEQ DD NO 10416) 5'-GCG CTG CCT TCT TCT CCT GG-3' (FRAG NO 1038) (SEQ LDNO 10417) 5'-GTC CTC GCC GGG GCC CTT GCT GCC CTG GCT GT-3' (FRAG NO 1039) (SEQ DD NO 10418)

5'-GCC CTG GGG GTC TGG GTT CGG CTG T-3' (FRAG NO 1040) (SEQ DD NO 10419) 5'-CCC CBG CBG GBC CBG TCC CBT CCB CBG CGT GTG BTG BGT BGC CBT TCT CCT GCB GCC GBG -3 ' (FRAG NO 1041) (SEQ ID NO 10420)

Human Cvclooxygenase-2 Nucleic Acid and Antisense Oligonucleotide Fragments 5'-GGG CGC GGG CGB GCB TCG C TTT GGG CTT TTC TCC TTT GGT T TGB GCG CCB GGB CCG CGC BCB GCB GCB GGG CGC GGG CGB GCB TCG CBG CGG CGG GCB

GGG 3' (FRAG NO 1716) (SEQ DD NO 11098)

5'-G GCB GGG -3' (FRAG NO 1717) (SEQ DD NO 11099)

5'-TCC TTT GGT T-3' (FRAG NO 1718) (SEQ DD NO 11100)

5'- GGG CGC GGG CGB GCB TCG C-3' (FRAG NO 1042) (SEQ DD O 10421) 5'- TTT GGG CTT TTC TCC TTT GGT T-3' (FRAG NO 1043) (SEQ DD NO 10422)

5'-TGB GCG CCB GGB CCG CGC BCB GCB GCB GGG CGC GGG CGB GCB TCG CBG CGG CGG GCB GGG -3' (FRAG NO 1044) (SEQ LD NO 10423)

Human Eosinophil Cationic Protein Nucleic Acid and Antisense Oligonucleotide Fragments

5'-CCT CCT TCC TGG TCT GTC TGC CBG BCB BBT TTG GGB BGT GBB CBG TTT TGG BBC CBT GTT TCC CBG TCT CTG BGC TGT GGC-3' (FRAG NO 1719) (SEQ DD NO 11101)

5'-TTC TCC TTT GGT T-3* (FRAG NO 1720) (SEQ ED NO 11102)

S'-T TTC TCC TTT GGT T-3' (FRAG NO 1721) (SEQ ID NO 11103)

5'- GGG CGC GGG CGB GCB TCG C-3' (FRAG NO 1042) (SEQ DD NO 10421)

5'- TTT GGG CTT TTC TCC TTT GGT T-3' (FRAG NO 1043) (SEQ ID NO 10422) 5'-TGB GCG CCB GGB CCG CGC BCB GCB GCB GGG CGC GGG CGB GCB TCG CBG CGG CGG GCB GGG -3'

(FRAG NO 1044) (SEQ DD NO 10423)

Human Eosinophil Derived Neurotoxin Nucleic Acid and Antisense Oligonucleotide Fragments

5'-GCC CTG CTG CTC TTT CTG CT TCC CTT GGT GGG TTG GGC C GCT GGT TGT TCT GGG GTT C TTG CTG CCC CTT CTG TCC C TGT TTG CTG GTG TCT GCG C 5'- CCC

CBB CBG BBG BBG CBG BCB BBT TTG GGB BGT GBB CBG TTT TGG BBC CBT GTT TCC TGT-3' (FRAG NO 1722) (SEQ DD NO 11104) 5'-TTC CTG T-3' (FRAG NO 1723) (SEQ ED NO 11105)

5'-CTC TTT CTG CT-3' (FRAG NO 1724) (SEQ DD NO 11106)

5'-CCC CTT CTG TCC C-3^> (FRAG NO 1725) (SEQ DDNO 11107)

5'- GCC CTG CTG CTC TTT CTG CT-3' (FRAG NO 1047) (SEQ ID NO 10424)

5'- TCC CTT GGT GGG TTG GGC C-3' (FRAG NO 1048) (SEQ DD NO 10425) 5'- GCT GGT TGT TCT GGG GTT C-3' (FRAG NO 1049) (SEQ DD NO 10427)

5'- TTG CTG CCC CTT CTG TCC C-3' (FRAG NO 1050) (SEQ ID NO 10426)

5'- TGT TTG CTG GTG TCT GCG C -3' (FRAG NO 1051) (SEQ DD NO 10428)

5'- CCC CBB CBG BBG BBG CBG BCB BBT TTG GGB BGT GBB CBG TTT TGG BBC CBT GTT TCC TGT-3' (FRAG NO 1052) (SEQ DD NO 10429)

Human Eosinophil Peroxidase Nucleic Acid and Antisense Oligonucleotide Fragments 5'-GCG CTC GGC CTG GTC CCG G GGG TCT CCT CTT GTT GTT GC TTG CGC CTC CTG CTG GGG GT CC CTC TGT TCT TGT TTT GGG GGC GGG CCC GGC CGT TGT CTT

G GTT TGG GGG TTT CCG TTG GGG TTC TCC TGG CCC GGG CCT TGC CC GGC CGT GGT CCC GGC TTC GTTCCT GTC TCC GTC TCG GCT CTT CTG GGG CCT TGC GCT GTC TTT GGT G 5'-GCB CCG TCC BGT GBT GGT GCG GTB CTT GTC GCT GCB GCG CTC GGC CTG GTC CCG GBG BGC CACCGCTCCT GTCAGCCAAC AAATATCCAT TGAGCGACAC CTGTGTCCCA GGTGCTGCTC TGGGCCCTGG GAGAAGTGCA TCAGTGGGCT TGGTAGTAGA GGGTAGGGAT GGAGTGAAGG GTAGGCAGGA AGAATGTCCC CAGGCTGGTA GGAGGTGGGG TGGGGGGTTT CAGTCTCAAA ACTCCCATGA AAACCAGAGA GAAGTTTCAG AACTCCACCC AAGAGGCTGG GTTTCTAGGG CCCAGAGCTG CCCTCCCCCA CCCTAGAATG GGCTATAAAA GTCCCTTCCC AGCTACGTCC AGAGAAGAGC TGGAGGAAGT GAGAGGTCGG CTGGGGGTCC TCAAAGTGAG

AGGGGAGCAG AGGATCCTCC CGTGCAGGCT GTGGATGTCA CTCACTTCCC AGCTGGTGAA GCCTCGCTGC AGAGATGCAT CTGCTCCCAG CCCTGGCAGG GGTCCTGGCC ACACTCGTCC TCGCCCAGCC CTGTGAGGGC ACTGACCCAG GTAATAGTCC CCTAGACAGG CAAGGAGGAG GGAGGGGAAA TGGAAGGGGA AGCACTTGGG TCTTGGAGGG GGTCTTGTGG CTTGCTGAAC CCTGAGTCCC CATCTCTTTG AACAGCCTCC CCTGGGGCAG TGGAGACCTC GGTCCTGCGA GACTGCATAG CAGAGGCCAA GTTGCTGGTG GATGCTGCCT ACAATTGGAC CCAGAAGAGG TGGACTTGGG TCTGGGGGCT GCATGGGCCT GGGAGGATCA GT TAATACCTTG TGGGGTCAGG GAGCCCATGT CCCGTGCTGA TGTTATTTCC CCACCAGGTC CGGGCTGTCT CCAACCAGAT TGTGCGCTTC CCCAATGAGA GACTGACCTC CGACCGTGGC CGAGCCCTCA

TGTTCATGCA GTGGGGCCAG TTCATTGACC ATGACCTGGA CTTCTCCCCG GAGTCCCCGG CCAGAGTGGC CTTCACTGCA GGCGTTGACT GTGAGAGGAC CTGCGCCCAG CTGCCCCCCT GCTTTCCCAT CAAGGTACCT ACCCTCAGCC AATCTCCCAT GCCCTTGTGT GGCCTCCCCC AAAGGCAAGG TGCTGGGGGT GGGGATCTGG AAGACTGGAG CACCATCCTT AAGGAGCTGC CTGTGGAGCT AGGGTATGAG ACAGAGACAC AAG CACTGTCTCC TCTTCCATCT CAGATCCCAC CCAATGACCC CCGCATCAAG AACCAGCGTG ACTGCATCCC TTTCTTCCGC TCGGCACCCT CATGCCCCCA AAACAAGAAC AGAGTCCGCA ACCAGATCAA CGCGCTCACC TCCTTTGTGG ACGCCAGCAT GGTGTATGGC AGTGAGGTCT CCCTCTCGCT GCGGCTCCGC AACCGGACCA ACTACCTGGG GCTGCTGGCC ATCAACCAGC GCTTTCAAGA CAACGGCCGG GCCCTGCTGC

CCTTCGACAA CCTGCACGAT GACCCCTGTC TCCTCACCAA CCGCTCGGCG CGCATCCCCT GCTTCCTGGC AGGTCAGACA GGGAGGAAGG TGGTGTCTTC CCAGGAAACA GCCATCCCTG GGGTCCCAAC TGGGAAGCAA TGGTGGGATG TGGTGAAGGT ACATGGTTTG GGACCTCAGT ATTAGGCACA CCATAAGCAT GGATCTGTGC AC TGAAGAGATG GAGGTCCAGT GAGGGCCAGG AGTTTGGCCC ACCCCGTCTC TCCCATCCCC AGCCCTGGGT CTACCCTGGT AGAAAGACAT TTCTCTGGGA AAGGCTGCAG TAAATCTGAG CTTGGGGTTT TCAAGGTGAC ACCCGATCAA CGGAAACCCC CAAACTGGCA GCCATGCACA CCCTCTTTAT GCGAGAGCAC AACCGGCTGG CCACCGAGCT GAGACGCCTG AATCCCCGGT GGAATGGAGA CAAACTGTAC AATGAGGCTC GGAAGATCAT GGGGGCCATG GTCCAGGTAA GGAGCTCTGC ATCCCAGCAT CCCCC

CTTTGTATCT CCACCCACCA ATAGTAAATT AATGTTGTCA CATTTGACGT GATGACAATA AAGAATATGT CTGAGCCACC CTTTGAAAAG GCAAGGGTAT GGGTGAGTAG CCTCTGGGGA ATGTTCCTCC TGTCTTCCCT TCCAGATCAT CACCTACCGA GACTTTCTGC CCCTGGTTCT GGGCAAGGCC CGGGCCAGGA GAACCCTGGG GCACTACAGG GGGTACTGCT CCAATGTGGA CCCACGGGTG GCCAATGTCT TCACCCTGGC CTTCCGCTTT GGCCACACAA TGCTCCAGCC CTTCATGTTC CGCTTGGACA GTCAGTACCG GGCCTCCGCA CCCAACTCGC ATGTCCCACT TAGCTCTGCC TTCTTTGCCA GCTGGCGGAT CGTGTATGAA GGTGACCAGG TTTTCCAGGG GGCAAATGGG GGTGAGGGTG GGGAGCATGC CCTCCCCTAG GTGG TCCAGCTGCT TCATGTCTCT CCAGAACTCT GTTTCCTGAC AAACGTTACT AACATACCCG ACTGGCTTGT CCAGCTCTGG

GCTAGCTTGG CATCATGTGA TAACCCAAGT AGCTTCCCAG AGGCTGGTCC AATCTGTGCT GCTCACATTC CCTGCCACCA GGGGGCATCG ACCCCATCCT CCGGGGCCTC ATGGCCACCC CTGCCAAGCT GAACCGTCAG GATGCCATGT TAGTGGATGA GCTCCGGGAC CGGCTGTTTC GGCAAGTGAG GAGGATTGGG CTGGACCTGG CAGCTCTCAA CATGCAACGA AGCCGGGACC ACGGCCTTCC AGGTGAGGGG GCTGTCCACC TCTTCTCCCA GCTTTGCTCG GGCCAGGCTG CTCAAGGGGT TCTGGGAAGA CCCTGGTACC CGACTGCCTG GTAGGTTCTG GTGGCAGAAA CGAGGTGTTT TCACCAAAAG ACAGCGCAAG GCCCTGAGCA GAATTTCCTT GTCTCGAATT ATATGTGACA ATACCGGTAT CACCACGGTT TCAAGGGACA TCTTCAGAGC CAACATCTAC CCTCGGGGCT TTGTGAACTG CAGCCGTATC CCCAGGTTGA ACCTATCAGC CTGGCGAGGG ACATGAGGCT

TCTGCAGGTA AGGGGAGGCC ACCTCCAGCA CCCTGGGCTG GTTAAGCCTC ACATCCTTCC CTGGATGGAT GGCTGAGTCC TCTTAGGTCT CTAAGCAGAG AAAACAGAAC TTGTCACTAG GTACTCTTTC CAAGTGGCTT CCCAATGTGC TAGTTTCTGG GCTGACAGTC AATTCCAGGC CCTAGGACTT TGGGGOGAAA TTAGGAGCAT CCAACTA GAATTCCGTG GCCAGGACCC CTGCCAGGGC ACTGACCCAG CCTCCCCTGG GGCAGTGGAG ACCTCGGTCC TGCGAGACTG CATAGCAGAG GCCAAGTTGC TGGTGGATGC TGCCTACAAT TGGACCCAGA AGAGCATCAA GCAGCGGCTT CGCAGCGGTT CAGCCAGCCC CATGGACCTC CTGTCCTACT TCAAACAACC GGTAGCAGCC ACCAGGACAG TTGTTCGGGC CGCAGATTAT ATGCATGTGG CTTTGGGGCT GCTTGAAGAG AAGTTACAAC CCCAGCGGTC CGGACCCTTC ATTGTCACTG ATGTGCTAAC AGAACCACAG

CTGCGGCTGC TGTCCCAGGC CAGTGGCTGT GCTCTCCGGG ACCAGGCCGA GCGCTGCAGC GACAAGTACC GCACCATCAC TGGACGGTGC AACAACAAGA GGAGACCCTT GCTAGGGGCC TCCAACCAGG CTCTGGCTCG CTGGCTGCCC GCCGAGTATG AGGATGGGCT GTCGCTCCCC TTCGGCTGGA CCCCCAGCAG GAGGCGCAAT GGCTTCCTTC TCCCTCTTGT CCGGGCTGTC TCCAACCAGA TTGTGCGCTT CCCCAATGAG AGACTGACCT CCGACCGTGG CCGAGCCCTC ATGTTCATGC AGTGGGGCCA GTTCATTGAC CATGACCTGG ACTTCTCCCC GGAGTCCCCG GCCAGAGTGG CCTTCACTGC AGGCGTTGAC TGTGAGAGGA CCTGCGCCCA GCTGCCCCCC TGCTTTCCCA TCAAGATCCC ACCCAATGAC CCCCGCATCA AGAACCAGCG TGACTGCATC CCTTTCTTCC GCTCGGCACC CTCATGCCCC CAAAACAAGA ACAGAGTCCG CAACCAGATC AACGCGCTCA

CCTCCTTTGT GGACGCCAGC ATGGTGTATG GCAGTGAGGT CTCCCTCTCG CTGCGGCTCC GCAACCGGAC CAACTACCTG GGGCTGCTGG CCATCAACCA GCGCTTTCAA GACAACGGCC GGGCCCTGCT GCCCTTCGAC AACCTGCACG ATGACCCCTG TCTCCTCACC AACCGCTCGG CGCGCATCCC CTGCTTCCTG GCAGGTGACA CCCGATCAAC GGAAACCCCC AAACTGGCAG CCATGCACAC CCTCTTTATG CGAGAGCACA ACCGGCTGGC CACCGAGCTG AGACGCCTGA ATCCCCGGTG GAATGGAGAC AAACTGTACA ATGAGGCTCG GAAGATCATG GGGGCCATGG TCCAGATCAT CACCTACCGA GACTTTCTGC CCCTGGTTCT GGGCAAGGCC CGGGCCAGGA GAACCCTGGG GCACTACAGG GGGTACTGCT CCAATGTGGA CCCACGGGTG GCCAATGTCT TCACCCTGGC CTTCCGCTTT GGCCACACAA TGCTCCAGCC CTTCATGTTC CGCTTGGACA GTCAGTACCG

GGCCTCCGCA CCCAACTCGC ATGTCCCACT TAGCTCTGCC TTCTTTGCCA GCTGGCGGAT CGTGTATGAA GGGGGCATCG ACCCCATCCT CCGGGGCCTC ATGGCCACCC CTGCCAAGCT GAACCGTCAG GATGCCATGT TAGTGGATGA GCTCCGGGAC CGGCTGTTTC GGCAAGTGAG GAGGATTGGG CTGGACCTGG CAGCTCTCAA CATGCAACGA AGCCGGGACC ACGGCCTTCC AGGGTACAAT GCTTGGAGGC GCTTCTGTGG GCTCTCCCAG CCCCGGAATT TGGCACAGCT TAGCCGGGTG CTGAAAAACC AGGACTTGGC AAGGAAGTTC CTGAATTTGT ATGGAACACC TGACAACATT GACATCTGGA TTGGGGCCAT CGCTGAGCCT CTTTTGCCGG GGGCTCGAGT GGGGCCTCTT CTGGCTTGTC TGTTCGAGAA CCAGTTCAGA AGAGCCGAGA CGGAGACAGG TTCTGGTGGC AGAACGAGGT GTTTTCACCA AAGACAGCGC AAGGCCCTGA GCAGAATTTC CTTGTCTCGA

ATTATATGTG ACAATACCGG TATCACCACG GTTTCAAGGG ACATCTTCAG AGCCAACATC TACCCTCGGG GCTTTGTGAA CTGCAGCCGT ATCCCCAGGT TGAACCTATC AGCCTGGCGA GGGACATGAG GCTTCTGCAG GAGTCTATCC CAAGTCTCCA ACTTTTGGAG ACAAGGGGAA GGGGAGGACC ATGAGGCTGC CTTGTCTCCC TGGAGCAAGT GCAGGCTCGT GACGCTTCTG CTGGCTACAG CTCAGAGCTG GGTTCCCCAG CCAGGAGTGA AGGCTGGGGG CTCCTATCAG CAATGGACCT TCCGCCTTGG GAGCCTCTTA GGTATTAGGC TATGAATCAG CGCCACGTGC AAAGGCTTGG GAGCCAAGCC ATGTGGTCTT GCACCCCAGG CAAGAAAAGT CAGCTGGAGG GTTTACAGCA CTTTCTACTG TTTCCCAGCC CTCCCTCCCC TCCCTCACCA TGACTAAGAG ACCACTCGGT CCTAGCCTCC AGACACCCCA CAATACTCCT CTGAGCCTGA GGCCAGGCAG CATGCTCTGC TTCTACCAAT AAAGCACTGC CGGAATTC-3' (FRAG NO 1726) (SEQ DD NO 12377)

5' CACCGCTCCT GTCAGCCAAC AAATATCCAT TGAGCGACAC CTGTGTCCCA GGTGCTGCTC TGGGCCCTGG GAGAAGTGCA TCAGTGGGCT TGGTAGTAGA GGGTAGGGAT GGAGTGAAGG GTAGGCAGGA AGAATGTCCC CAGGCTGGTA GGAGGTGGGG TGGGGGGTTT CAGTCTCAAA ACTCCCATGA AAACCAGAGA

GAAGTTTCAG AACTCCACCC AAGAGGCTGG GTTTCTAGGG CCCAGAGCTG CCCTCCCCCA CCCTAGAATG GGCTATAAAA GTCCCTTCCC AGCTACGTCC AGAGAAGAGC TGGAGGAAGT GAGAGGTCGG CTGGGGGTCC TCAAAGTGAG AGGGGAGCAG AGGATCCTCC CGTGCAGGCT GTGGATGTCA CTCACTTCCC AGCTGGTGAA GCCTCGCTGC AGAGATGCAT CTGCTCCCAG CCCTGGCAGG GGTCCTGGCC ACACTCGTCC TCGCCCAGCC CTGTGAGGGC ACTGACCCAG GTAATAGTCC CCTAGACAGG CAAGGAGGAG GGAGGGGAAA TGGAAGGGGA AGCACTTGGG TCTTGGAGGG GGTCTTGTGG CTTGCTGAAC CCTGAGTCCC CATCTCTTTG AACAGCCTCC CCTGGGGCAG TGGAGACCTC GGTCCTGCGA GACTGCATAG CAGAGGCCAA GTTGCTGGTG GATGCTGCCT ACAATTGGAC CCAGAAGAGG TGGACTTGGG

TCTGGGGGCT GCATGGGCCT GGGAGGATCA GT-3' (FRAG NO J(SEQ DD NO 11852)

5'-TAATACCTTG TGGGGTCAGG GAGCCCATGT CCCGTGCTGA TGTTATTTCC CCACCAGGTC CGGGCTGTCT CCAACCAGAT TGTGCGCTTC CCCAATGAGA GACTGACCTC CGACCGTGGC CGAGCCCTCA TGTTCATGCA GTGGGGCCAG TTCATTGACC ATGACCTGGA CTTCTCCCCG GAGTCCCCGG CCAGAGTGGC CTTCACTGCA GGCGTTGACT GTGAGAGGAC CTGCGCCCAG CTGCCCCCCT GCTTTCCCAT CAAGGTACCT ACCCTCAGCC AATCTCCCAT GCCCTTGTGT GGCCTCCCCC AAAGGCAAGG TGCTGGGGGT GGGGATCTGG AAGACTGGAG CACCATCCTT AAGGAGCTGC CTGTGGAGCT AGGGTATGAG ACAGAGACAC AAG-3' (FRAG NO J(SEQ DD NO 11853)

5' CACTGTCTCC TCTTCCATCT CAGATCCCAC CCAATGACCC CCGCATCAAG AACCAGCGTG ACTGCATCCC TTTCTTCCGC TCGGCACCCT CATGCCCCCA AAACAAGAAC AGAGTCCGCA ACCAGATCAA CGCGCTCACC TCCTTTGTGG ACGCCAGCAT GGTGTATGGC AGTGAGGTCT CCCTCTCGCT GCGGCTCCGC AACCGGACCA ACTACCTGGG GCTGCTGGCC ATCAACCAGC GCTTTCAAGA CAACGGCCGG GCCCTGCTGC CCTTCGACAA CCTGCACGAT GACCCCTGTC TCCTCACCAA CCGCTCGGCG CGCATCCCCT GCTTCCTGGC AGGTCAGACA GGGAGGAAGG TGGTGTCTTC CCAGGAAACA GCCATCCCTG GGGTCCCAAC TGGGAAGCAA TGGTGGGATG TGGTGAAGGT ACATGGTTTG GGACCTCAGT ATTAGGCACA CCATAAGCAT GGATCTGTGC AC-3' (FRAG NO J(SEQ DD NO 11854)

5'-TGAAGAGATG GAGGTCCAGT GAGGGCCAGG AGTTTGGCCC ACCCCGTCTC TCCCATCCCC AGCCCTGGGT CTACCCTGGT AGAAAGACAT TTCTCTGGGA AAGGCTGCAG TAAATCTGAG CTTGGGGTTT TCAAGGTGAC ACCCGATCAA CGGAAACCCC CAAACTGGCA GCCATGCACA CCCTCTTTAT GCGAGAGCAC AACCGGCTGG CCACCGAGCT GAGACGCCTG AATCCCCGGT GGAATGGAGA CAAACTGTAC AATGAGGCTC GGAAGATCAT GGGGGCCATG GTCCAGGTAA GGAGCTCTGC ATCCCAGCAT CCCCC-3' (FRAGNO J(SEQ D NO 11855) 5'-CTTTGTATCT CCACCCACCA ATAGTAAATT AATGTTGTCA CATTTGACGT GATGACAATA AAGAATATGT CTGAGCCACC CTTTGAAAAG GCAAGGGTAT

GGGTGAGTAG CCTCTGGGGA ATGTTCCTCC TGTCTTCCCT TCCAGATCAT CACCTACCGA GACTTTCTGC CCCTGGTTCT GGGCAAGGCC CGGGCCAGGA GAACCCTGGG GCACTACAGG GGGTACTGCT CCAATGTGGA CCCACGGGTG GCCAATGTCT TCACCCTGGC CTTCCGCTTT GGCCACACAA TGCTCCAGCC CTTCATGTTC CGCTTGGACA GTCAGTACCG GGCCTCCGCA CCCAACTCGC ATGTCCCACT TAGCTCTGCC TTCTTTGCCA GCTGGCGGAT CGTGTATGAA GGTGACCAGG TTTTCCAGGG GGCAAATGGG GGTGAGGGTG GGGAGCATGC CCTCCCCTAG GTGG 3' (FRAG NO _)(SEQ DD NO 11856) 5'-TCCAGCTGCT TCATGTCTCT CCAGAACTCT GTTTCCTGAC AAACGTTACT AACATACCCG ACTGGCTTGT CCAGCTCTGG GCTAGCTTGG CATCATGTGA TAACCCAAGT

AGCTTCCCAG AGGCTGGTCC AATCTGTGCT GCTCACATTC CCTGCCACCA GGGGGCATCG ACCCCATCCT CCGGGGCCTC ATGGCCACCC CTGCCAAGCT GAACCGTCAG GATGCCATGT TAGTGGATGA GCTCCGGGAC CGGCTGTTTC GGCAAGTGAG GAGGATTGGG CTGGACCTGG CAGCTCTCAA CATGCAACGA AGCCGGGACC ACGGCCTTCC AGGTGAGGGG GCTGTCCACC TCTTCTCCCA GCTTTGCTCG GGCCAGGCTG CTCAAGGGGT TCTGGGAAGA CCCTGGTACC-3' (FRAG O J(SEQ DD NO 11857) 5'-CGACTGCCTG GTAGGTTCTG GTGGCAGAAA CGAGGTGTTT TCACCAAAAG ACAGCGCAAG GCCCTGAGCA GAATTTCCTT GTCTCGAATT ATATGTGACA ATACCGGTAT CACCACGGTT TCAAGGGACA TCTTCAGAGC CAACATCTAC CCTCGGGGCT TTGTGAACTG CAGCCGTATC CCCAGGTTGA ACCTATCAGC CTGGCGAGGG

ACATGAGGCT TCTGCAGGTA AGGGGAGGCC ACCTCCAGCA CCCTGGGCTG GTTAAGCCTC ACATCCTTCC CTGGATGGAT GGCTGAGTCC TCTTAGGTCT CTAAGCAGAG AAAACAGAAC TTGTCACTAG GTACTCTTTC CAAGTGGCTT CCCAATGTGC TAGTTTCTGG GCTGACAGTC AATTCCAGGC CCTAGGACTT TGGGGGGAAA TTAGGAGCAT CCAACTA-3' (FRAGNO J(SEQ DD NO 11858) 5'-GAATTCCGTG GCCAGGACCC CTGCCAGGGC ACTGACCCAG CCTCCCCTGG GGCAGTGGAG ACCTCGGTCC TGCGAGACTG CATAGCAGAG GCCAAGTTGC TGGTGGATGC TGCCTACAAT TGGACCCAGA AGAGCATCAA GCAGCGGCTT CGCAGCGGTT CAGCCAGCCC CATGGACCTC CTGTCCTACT TCAAACAACC GGTAGCAGCC

ACCAGGACAG TTGTTCGGGC CGCAGATTAT ATGCATGTGG CTTTGGGGCT GCTTGAAGAG AAGTTACAAC CCCAGCGGTC CGGACCCTTC ATTGTCACTG ATGTGCTAAC AGAACCACAG CTGCGGCTGC TGTCCCAGGC CAGTGGCTGT GCTCTCCGGG ACCAGGCCGA GCGCTGCAGC GACAAGTACC GCACCATCAC TGGACGGTGC AACAACAAGA GGAGACCCTT GCTAGGGGCC TCCAACCAGG CTCTGGCTCG CTGGCTGCCC GCCGAGTATG AGGATGGGCT GTCGCTCCCC TTCGGCTGGA CCCCCAGCAG GAGGCGCAAT GGCTTCCTTC TCCCTCTTGT CCGGGCTGTC TCCAACCAGA TTGTGCGCTT CCCCAATGAG AGACTGACCT CCGACCGTGG CCGAGCCCTC ATGTTCATGC AGTGGGGCCA GTTCATTGAC CATGACCTGG ACTTCTCCCC GGAGTCCCCG GCCAGAGTGG CCTTCACTGC AGGCGTTGAC TGTGAGAGGA CCTGCGCCCA GCTGCCCCCC

TGCTTTCCCA TCAAGATCCC ACCCAATGAC CCCCGCATCA AGAACCAGCG TGACTGCATC CCTTTCTTCC GCTCGGCACC CTCATGCCCC CAAAACAAGA ACAGAGTCCG CAACCAGATC AACGCGCTCA CCTCCTTTGT GGACGCCAGC ATGGTGTATG GCAGTGAGGT CTCCCTCTCG CTGCGGCTCC GCAACCGGAC CAACTACCTG GGGCTGCTGG CCATCAACCA GCGCTTTCAA GACAACGGCC GGGCCCTGCT GCCCTTCGAC AACCTGCACG ATGACCCCTG TCTCCTCACC AACCGCTCGG CGCGCATCCC CTGCTTCCTG GCAGGTGACA CCCGATCAAC GGAAACCCCC AAACTGGCAG CCATGCACAC CCTCTTTATG CGAGAGCACA ACCGGCTGGC CACCGAGCTG AGACGCCTGA ATCCCCGGTG GAATGGAGAC AAACTGTACA ATGAGGCTCG GAAGATCATG GGGGCCATGG TCCAGATCAT CACCTACCGA GACTTTCTGC CCCTGGTTCT GGGCAAGGCC CGGGCCAGGA

GAACCCTGGG GCACTACAGG GGGTACTGCT CCAATGTGGA CCCACGGGTG GCCAATGTCT TCACCCTGGC CTTCCGCTTT GGCCACACAA TGCTCCAGCC CTTCATGTTC CGCTTGGACA GTCAGTACCG GGCCTCCGCA CCCAACTCGC ATGTCCCACT TAGCTCTGCC TTCTTTGCCA GCTGGCGGAT CGTGTATGAA GGGGGCATCG ACCCCATCCT CCGGGGCCTC ATGGCCACCC CTGCCAAGCT GAACCGTCAG GATGCCATGT TAGTGGATGA GCTCCGGGAC CGGCTGTTTC GGCAAGTGAG GAGGATTGGG CTGGACCTGG CAGCTCTCAA CATGCAACGA AGCCGGGACC ACGGCCTTCC AGGGTACAAT GCTTGGAGGC GCTTCTGTGG GCTCTCCCAG CCCCGGAATT TGGCACAGCT TAGCCGGGTG CTGAAAAACC AGGACTTGGC AAGGAAGTTC CTGAATTTGT ATGGAACACC TGACAACATT GACATCTGGA TTGGGGCCAT CGCTGAGCCT CTTTTGCCGG GGGCTCGAGT

GGGGCCTCTT CTGGCTTGTC TGTTCGAGAA CCAGTTCAGA AGAGCCGAGA CGGAGACAGG TTCTGGTGGC AGAACGAGGT GTTTTCACCA AAGACAGCGC AAGGCCCTGA GCAGAATTTC CTTGTCTCGA ATTATATGTG ACAATACCGG TATCACCACG GTTTCAAGGG ACATCTTCAG AGCCAACATC TACCCTCGGG GCTTTGTGAA CTGCAGCCGT ATCCCCAGGT TGAACCTATC AGCCTGGCGA GGGACATGAG GCTTCTGCAG GAGTCTATCC CAAGTCTCCA ACTTTTGGAG ACAAGGGGAA GGGGAGGACC ATGAGGCTGC CTTGTCTCCC TGGAGCAAGT GCAGGCTCGT GACGCTTCTG CTGGCTACAG CTCAGAGCTG GGTTCCCCAG CCAGGAGTGA AGGCTGGGGG CTCCTATCAG CAATGGACCT TCCGCCTTGG GAGCCTCTTA GGTATTAGGC TATGAATCAG CGCCACGTGC AAAGGCTTGG GAGCCAAGCC ATGTGGTCTT GCACCCCAGG CAAGAAAAGT CAGCTGGAGG

GTTTACAGCA CTTTCTACTG TTTCCCAGCC CTCCCTCCCC TCCCTCACCA TGACTAAGAG ACCACTCGGT CCTAGCCTCC AGACACCCCA CAATACTCCT CTGAGCCTGA GGCCAGGCAG CATGCTCTGC TTCTACCAAT AAAGCACTGC CGGAATTC-3' (FRAG NO J(SEQ ID NO 11859) 5'-TC GGC CTG GTC CCG G-3' (FRAG NO 1727) (SEQ ED NO 11109) 5'-TGG GGG TTT CCGTTG-3' (FRAG NO 1728) (SEQ DD NO 11110) 5'-TG GTC CCG GBG BGC -3' (FRAG NO 1729) (SEQ DD O 11111)

5'-GCG CTC GGC CTG GTC CCG G-3' (FRAG NO 1053) (SEQ DD NO 10430) 5'-GGG TCT CCT CTT GTT GTT GC-3' (FRAG NO 1054) (SEQ DD NO 10431) 5'- TTG CGC CTC CTG CTG GGG GT CC-3' (FRAG NO 1055) (SEQ ID NO 10432) 5'-CTC TGT TCT TGT TTT GGG GGC-3' (FRAG NO 1056) (SEQ ED NO 10433) 5'-GGG CCC GGC CGT TGT CTT G-3' (FRAG NO 1057) (SEQ DD NO 10434)

5'-GTT TGG GGG TTT CCG TTG-3' (FRAG NO 1058) (SEQ DD NO 10435) 5'-GGG TTC TCC TGG CCC GGG CCT TGC CC-3' (FRAG NO 1059)(SEQ DD NO 10436) 5'-GGC CGT GGT CCC GGC TTC GTT GC-3' (FRAG NO 1060) (SEQ DD NO 10437) 5'-CCT GTC TCC GTC TCG GCT CTT CTG-3' (FRAG NO 1061) (SEQ ID NO 10438) 5'-GGG CCT TGC GCT GTC TTT GGT G-3' (FRAG NO 1062) (SEQ DD NO 10439)

5'-GCB CCG TCC BGT GBT GGT GCG GTB CTT GTC GCT GCB GCG CTC GGC CTG GTC CCG GBG BGC -3' (FRAG NO 1063) (SEQ ID NO 10440) Human Intercellular Adhesion Molecule-1 (ICAM-1) Nucleic Acid and Antisense Oligonucleotide Fragments

5'-GCG CGG GCC GGG GGC TGC TGG G GGT TGG CCC GGG GTG CCC C GCC GCT GGG TGC CCT CGT CCT CTG CGG TC GTG TCT CCT GGC TCT GGT TCC CC GCT GCG CCC GTT GTC CTC TGG GGT GGC CTT C GCT CCC GGG TCT GGT TCT TGT GT TGG GGG TCC CTT TTT GGG CCT GTT GT GGC GTG GCT TGT GTG TTC GGT TTC TGC

CCT GTC CTC CGG CGT CCC CGG BGC CTC CCC GGG GCB GGB TGB CTT TTG BGG GGG BCB CBG BTG TCT GGG CBT TGC CBG GTC CTG GGB BCB GBG CCC CGB GCB

GGB CCB GGB GTG CGG GCB GCG CGG GCC GGG GGC TGC TGG GBG CCB TBG CGB GGC TGB G-3' (FRAG NO 1730) (SEQ DD NO 11112)

5'-GGG GGC TGC TGG G-3' (FRAG NO 1731) (SEQ ED NO 11113)

5'-T GTC CTC CGG CGT CCC-3' (FRAG NO 1732) (SEQ ED NO 11114) 5'-G CCB TBG CGB GGC TGB G-3 ' (FRAG NO 1733) (SEQ ID NO 11115)

5'-CTC TGG GGT GGC CTT C-3' (FRAG NO 1734) (SEQ ED NO 11116)

5'-GCG CGG GCC GGG GGC TGC TGG G-3' (FRAG NO 1064) (SEQ DD NO 10441)

5'-GGT TGG CCC GGG GTG CCC C-3' (FRAG NO 1065) (SEQ DD NO 10442)

5'-GCC GCT GGG TGC CCT CGT CCT CTG CGG TC-3' (FRAG NO 1066) (SEQ ID NO 10443) 5'-GTG TCT CCT GGC TCT GGT TCC CC-3' (FRAG NO 1067) (SEQ DD NO 10444)

5'-GCT GCG CCC GTT GTC CTC TGG GGT GGC CTT C-3' (FRAG NO 1068) (SEQ DD NO 10445)

5'-GCT CCC GGG TCT GGT TCT TGT GT-3' (FRAG NO 1069) (SEQ ED NO 10446)

5'-TGG GGG TCC CTT TTT GGG CCT GTT GT-3' (FRAG NO 1070) (SEQ ED NO 10447)

5'-GGC GTG GCT TGT GTG TTC GGT TTC-3' (FRAG NO 1071) (SEQ DD NO 10448) 5'-TGC CCT GTC CTC CGG CGT CCC-3' (FRAG NO 1072) (SEQ ID NO 10449)

5'- CGG BGC CTC CCC GGG GCB GGB TGB CTT TTG BGG GGG BCB CBG BTG TCT GGG CBT TGC CBG GTC CTG GGB BCB GBG CCC CGB GCB GGB CCB GGB GTG CGG

GCB GCG CGG GCC GGG GGC TGC TGG GBG CCB TBG CGB GGC TGB G-3'?7 (FRAG NO 1073) (SEQ DD NO 10450)

Human Vascular Cell Adhesion Molecule 1 (VCAM-lt Nucleic Acid and Oligonucleotide Fragments

5'-CCT CTT TTC TGT TTT TCC C CTC TGC CTT TGT TTG GGT TCG CTT CCT TTC TGC TTC TTC C CTG TGT CTC CTG TCT CCG CTT TTT TCT TC GTC TTT GTT GTT TTC TCT TCC TTG CTG BGC BBG BTB TCT BGB TTC TGG GGT GGT CTC GBT TTT BBBB GCT TGB GBB GCT GCB BBC BTT BTC CBB BGT BTB TTT GBG GCT CCB BGG BTC BCG BCC BTC TTC CCB GGC BTT TTB BGT TGC TGT CGT-3'(FRAG NO 1735)(SEQ DD NO 11117) 5'-C TGT CGT-3' (FRAG NO 1736) (SEQ ID NO 1 II 18)

5'-TGC TTC TTC C-3' (FRAG NO 1737) (SEQ D NO 11119)

HSVCAMIASI 5'-CCT CTT TTC TGT TTT TCC C-3' (FRAG NO 1074) (SEQ DD NO 10451) HSVCAM1AS2 5'-CTC TGC CTT TGT TTG GGT TCG-3' (FRAG NO 1075) (SEQ ED NO 10452) HSVCAM1AS3 5'-CTT CCT TTC TGC TTC TTC C-3' (FRAG NO 1076) (SEQ DD O 10453) HSVCAM1AS4 5'-CTG TGT CTC CTG TCT CCG CTT TTT TCT TC-3' (FRAG NO 1077) (SEQ DD NO 10454)

HSVCAM1AS5 5'-GTC TTT GTT GTT TTC TCT TCC TTG-3' (FRAG NO 1078) (SEQ DD NO 10455)

CTG BGC BBG BTB TCT BGB TTC TGG GGT GGT CTC GBT TTT BBBB GCT TGB GBB GCT GCB BBC BTT BTC CBB BGT BTB TTT GBG GCT CCB BGG BTC BCG BCC BTC TTC CCB GGC BTT TTB BGT TGC TGT CGT(FRAG NO 1079)(SEQ DD NO 10456)

Human Endothelial Leukocyte Adhesion MoleculetELAM-l) Nucleic Acid and Antisense Oligonucleotide Fragments

5'-BBG TGB GBG CTG BGB GBB BCT GTG BBG CBB TCB TGB CTT CBB GBG TTC TTT TCB CCC GTT CTT GGC TTC TTC TGT C CGT TGG CTT CTC GTT GTC CC TGT GGG CTT CTC GTT GTC CC CCC TTC GGG GGC TGG TGG GGC CGT CCT TGC CTG CTG G GTT CTT GGC TTC TTC TGT CCG T TGG CTT CTC GTT GTC CC TGT GGG CTT CTC GTT GTC CC CCC TTC GGG GGC TGG TGG GGC CGT CCT TGC CTG CTG G CCTGAGACAG AGGCAGCAGT GATACCCACC TGAGAGATCC TGTGTTTGAA CAACTGCTTC CCAAAACGGA AAGTATTTCA AGCCTAAACC TTTGGGTGAA AAGAACTCTT GAAGTCATGA TTGCTTCACA GTTTCTCTCA GCTCTCACTT TGGTGCTTCT CATTAAAGAG AGTGGAGCCT GGTCTTACAA CACCTCCACG GAAGCTATGA CTTATGATGA GGCCAGTGCT TATTGTCAGC AAAGGTACAC ACACCTGGTT GCAATTCAAA ACAAAGAAGA

GATTGAGTAC CTAAACTCCA TATTGAGCTA TTCACCAAGT TATTACTGGA TTGGAATCAG AAAAGTCAAC AATGTGTGGG TCTGGGTAGG AACCCAGAAA CCTCTGACAG AAGAAGCCAA GAACTGGGCT CCAGGTGAAC CCAACAATAG GCAAAAAGAT GAGGACTGCG TGGAGATCTA CATCAAGAGA GAAAAAGATG TGGGCATGTG GAATGATGAG AGGTGCAGCA AGAAGAAGCT TGCCCTATGC TACACAGCTG CCTGTACCAA TACATCCTGC AGTGGCCACG GTGAATGTGT AGAGACCATC AATAATTACA CTTGCAAGTG TGACCCTGGC TTCAGTGGAC TCAAGTGTGA GCAAATTGTG AACTGTACAG CCCTGGAATC CCCTGAGCAT GGAAGCCTGG TTTGCAGTCA CCCACTGGGA AACTTCAGCT ACAATTCTTC CTGCTCTATC AGCTGTGATA GGGGTT ACCT GCCAAGCAGC ATGGAGACCA TGCAGTGTAT GTCCTCTGGA GAATGGAGTG CTCCTATTCC

AGCCTGCAAT GTGGTTGAGT GTGATGCTGT GACAAATCCA GCCAATGGGT TCGTGGAATG TTTCCAAAAC CCTGGAAGCT TCCCATGGAA CACAACCTGT ACATTTGACT GTGAAGAAGG ATTTGAACTA ATGGGAGCCC AGAGCCTTCA GTGTACCTCA TCTGGGAATT GGGACAACGA GAAGCCAACG TGTAAAGCTG TGACATGCAG GGCCGTCCGC CAGCCTCAGA ATGGCTCTGT GAGGTGCAGC CATTCCCCTG CTGGAGAGTT CACCTTCAAA TCATCCTGCA ACTTCACCTG TGAGGAAGGC TTCATGTTGC AGGGACCAGC CCAGGTTGAA TGCACCACTC AAGGGCAGTG GACACAGCAA ATCCCAGTTT GTGAAGCTTT CCAGTGCACA GCCTTGTCCA ACCCCGAGCG AGGCTACATG AATTGTCTTC CTAGTGCTTC TGGCAGTTTC CGTTATGGGT CCAGCTGTGA GTTCTCCTGT GAGCAGGGTT TTGTGTTGAA GGGATCCAAA AGGCTCCAAT GTGGCCCCAC AGGGGAGTGG

GACAACGAGA AGCCCACATG TGAAGCTGTG AGATGCGATG CTGTCCACCA GCCCCCGAAG GGTTTGGTGA GGTGTGCTCA TTCCCCTATT GGAGAATTCA CCTACAAGTC CTCTTGTGCC TTCAGCTGTG AGGAGGGATT TGAATTATAT GGATCAACTC AACTTGAGTG CACATCTCAG GGACAATGGA CAGAAGAGGT TCCTTCCTGC CAAGTGGTAA AATGTTCAAG CCTGGCAGTT CCGGGAAAGA TCAACATGAG CTGCAGTGGG GAGCCCGTGT TTGGCACTGT GTGCAAGTTC GCCTGTCCTG AAGGATGGAC GCTCAATGGC TCTGCAGCTC GGACATGTGG AGCCACAGGA CACTGGTCTG GCCTGCTACC TACCTGTGAA GCTCCCACTG AGTCCAACAT TCCCTTGGTA GCTGGACTTT CTGCTGCTGG ACTCTCCCTC CTGACATTAG CACCATTTCT CCTCTGGCTT CGGAAATGCT TACGGAAAGC AAAGAAATTT GTTCCTGCCA GCAGCTGCCA AAGCCTTGAA TCAGACGGAA

GCTACCAAAA GCCTTCTTAC ATCCTTTAAG TTCAAAAGAA TCAGAAACAG GTGCATCTGG GGAACTAGAG GGATACACTG AAGTTAACAG AGACAGATAA CTCTCCTCGG GTCTCTGGCC CTTCTTGCCT ACTATGCCAG ATGCCTTTAT GGCTGAAACC GCAACACCCA TCACCACTTC AATAGATCAA AGTCCAGCAG GCAAGGACGG CCTTCAACTG AAAAGACTCA GTGTTCCCTT TCCTACTCTC AGGATCAAGA AAGTGTTGGC TAATGAAGGG AAAGGATATT TTCTTCCAAG CAAAGGTGAA GAGACCAAGA CTCTGAAATC TCAGAATTCC TTTTCTAACT CTCCCTTGCT CGCTGTAAAA TCTTGGCACA GAAACACAAT ATTTTGTGGC TTTCTTTCTT TTGCCCTTCA CAGTGTTTCG ACAGCTGATT ACACAGTTGC TGTCATAAGA ATGAATAATA ATTATCCAGA GTTTAGAGGA AAAAAATGAC TAAAAATATT ATAACTTAAA AAAATGACAG ATGTTGAATG CCCACAGGCA

AATGCATGGA GGGTTGTTAA TGGTGCAAAT CCTACTGAAT GCTCTGTGCG AGGGTTACTA TGCACAATTT AATCACTTTC ATCCCTATGG GATTCAGTGC TTCTTAAAGA GTTCTTAAGG ATTGTGATAT TTTTACTTGC ATTGAATATA TTATAATCTT CCATACTTCT TCATTCAATA CAAGTGTGGT AGGGACTTAA AAAACTTGTA AATGCTGTCA ACTATGATAT GGTAAAAGTT ACTTATTCTA GATTACCCCC TCATTGTTTA TTAACAAATT ATGTTACATC TGTTTTAAAT TTATTTCAAA AAGGGAAACT ATTGTCCCCT AGCAAGGCAT GATGTTAACC AGAATAAAGT TCTGAGTGTT TTTACTACAG TTGTTTTTTG AAAACATGGT AGAATTGGAG AGTAAAAACT GAATGGAAGG TTTGTATATT GTCAGATATT TTTTCAGAAA TATGTGGTTT CCACGATGAA AAACTTCCAT GAGGCCAAAC GTTTTGAACT AATAAAAGCA TAAATGCAAA CACACAAAGG TATAATTTTA

TGAATGTCTT TGTTGGAAAA GAATACAGAA AGATGGATGT GCTTTGCATT CCTACAAAGA TGTTTGTCAG ATGTGATATG TAAACATAAT TCTTGTATAT TATGGAAGAT TTTAAATTCA CAATAGAAAC TCACCATGTA AAAGAGTCAT CTGGTAGATT TTTAACGAAT GAAGATGTCT AATAGTTATT CCCTATTTGT TTTCTTCTGT ATGTTAGGGT GCTCTGGAAG AGAGGAATGC CTGTGTGAGC AAGCATTTAT GTTTATTTAT AAGCAGATTT AACAATTCCA AAGGAATCTC CAGTTTTCAG TTGATCACTG GCAATGAAAA ATTCTCAGTC AGTAATTGCC AAAGCTGCTC TAGCCTTGAG GAGTGTGAGA ATCAAAACTC TCCTACACTT CCATTAACTT AGCATGTGTT GAAAAAAAAA GTTTCAGAGA AGTTCTGGCT GAACACTGGC AACGACAAAG CCAACAGTCA AAACAGAGAT GTGATAAGGA TCAGAACAGC AGAGGTTCTT TTAAAGGGGC AGAAAAACTC

TGGGAAATAA GAGAGAACAA CTACTGTGAT CAGGCTATGT ATGGAATACA GTGTTATTTT CTTTGAAATT GTTTAAGTGT TGTAAATATT TATGTAAACT GCATTAGAAA TTAGCTGTGT GAAATACCAG TGTGGTTTGT GTTTGAGTTT TATTGAGAAT TTTAAATTAT AACTTAAAAT ATTTTATAAT TTTTAAAGTA TATATTTATT TAAGCTTATG TCAGACCTAT TTGACATAAC ACTATAAAGG TTGACAATAA ATGTGCTTAT GTTT GATCAAAATT TTTACCTATT ATGCATTTGA TATATAAATA AGTATATAAA TGCACACACA GACACAGCAA TGATGGTGAA CAGTCTTCAT ACAATTATAT GGATGAATCT CATAAAATGC TGAGTTAAAG AAATCAGACC AAAGAACATA TACTGAAAGA TTCTCTCTAT ATACAAAGTT CAAAAATAGG TGGACCAATT CATGGTGGTG TTAGAAATCA GAAGAGAGGC TACCTTTGTG GGGAGGGGAC AGTTTAATGC CCAGAAGCGG

TAAATAAGGA ATCCTCTGGG GAGTGGTAAT GATCTGGATG CTGGCTACAG GATGTGTTGG TTGTAAAAAT GCATTTTTTT ATATCTAGCT TTTTCCATGT GTATATTATA CTTCAAAGAA GTTCAGTTAA TAATTTCTCA TGTCACTGTA GAGTAGCTCA GTTAGCCCCA GCAAGCCTCT GGCTTAATCT TGTTTTACCT TAAGCCATCA GTCATTTACA AGTAGGAAAA TTCACAGGGA AAGTTAGAGT ATAAAATCCA GAATGAAGGT TTACTGGGTA AGAGTCTCTC CATTTTCCAA AGCCCGTTTA TTTCTTGATT CCAGTTCTTA AGAAGTCTCA GCATTGTGTC TTTTTCATGT ATCTTACAAG AAGACAGCAT GTGCTTCTAA CACCTGATAC ATTGTATCTA CCAGCACTTG GTAAACAGAA AAGAACCACA TTTTTCTTGT AGGAGAAATT TGGTGCCTAT TTCCTACCAG GCACCAATAA GTGGGACCAA TAGGTGGGAT TAAAGATACA GTAGAAAGTA TTTAAAACTT GCCAGGGGGC

AATAGTCTGA AAATAAGTAA ATTGGTGCTA TAGAATGGAA GTTACAGGCT TCTTTCTTTT TTCCCACAAG ATCTGCTCCT TGAGCCCCTA GAGACTTTTC TGTCTGTTAC TGTTTCTTCA TTCCTCATCT GCAGAGCCAG CCCTGAGAAG TGCAGACCAA AGCCAGGGAA GGCTCTGCAA AGATGTACAA ATGGAAGTCA CCTTAATAAG CTCTGACTGC TGCGCATAAT ACATTTCACT CAAAAGAGGG GTTAAACAAT GGAACAGAAT ACAGAGGCCA GAAATAATGC TGAACACTGA CAACCATCTG ATCTTTGACA AAATCCACAA AAACAAGCAA TGGAGAAAGG ACTCCCTATT CCATAATGGT GCTGGGATAA CTGTCTAGCT ATATACAGAA GATTGAACCT GGGCCCCTTC CTTACATCAT ATACAAAAAA TAACTCAAGA TGGAGTAAAG ACTTAAATCT AAAACCAAAC ACTATAAAAA CCCTGGAAGA TAGCCTGGGA AATACCATTC TGGACATAGG ACCTGGCAAA GACTTCATGA

CAAGACACCA AAAGCAATAG CAACAAAAAC CAAATTGACT AATGAAACTA ATGAAACTCT TTAGTTGTAC AACAGATAGT TTATCTGTAC AACAAAATAA ACTATCAACA GAGTAAACAA CCTACAGAAT GGAAAAATTT TTTGCAAACT ATGCATCTGA CAAAGGTCTA ATATCCAGAA TCTATAAGGA ATTTAAACAA ATTTACAAGC AAAAAAATGA CCTCATTAAA AAGTGGGCAA AGGACATGAA CAGATGCTTT TCAAAATAAG ACATTCACAC ATCCAACAAC CATATGAAAA GATGTTTAAC ATCACTAATC ATTAGAGGAA TACAAATCAA AAGCATAATA AGATACCATC TAATACCAGT AGGAATGACT ACTATTAAAA AGTCAGACAA TAACAGATGC TGGTGAAGGT TGTGGAGAAA AGGGAATGTT TATGCACTGC TAGTGGGAAT GTAAACTAGT TCAGCCATTG TGGAAGAGAG TGTGGTGATT CCTCAAAGAA TGTAAAACCG AACTGCCTTT CAATCCAGCA ATCCCATTAT

TGGATATACA CCAAAAGGAA TAGAAATTGT TTTACCGTAA AGGCGCATGC ATGCATATGT TCATTACAGC ACTATTTACG ATAGCAAAGA CATGGAATCG TCTAAATGCC CATCAGTGGT AGACTAGCTA AAAAAAAAAA AATGTGGTAC ATATACATCA CAGAATAGTA TGCAGCCATA AAAATGAACA AGATCATCAT GTCCTTTGCA GCAACATGGA TGTAGTTGGA GGCCATTATC CTAAGCAAAT TAATGCAGGA ACAGAAAGCC AAATACCACA TGTTCTCATT TATAAGTGAC AGCTAAATAT TGAGTACACA TGGACACAAA GAAGGGAACA ATAGACATGG GACCTACTTG AGAATAGAGG GTGGGAGGAG GGTGAGGATC AAAAAGTACC CATAGGACAC TGTGCTTATT ACCTGGGTGA TGAAATAATT TGCACACCAA ACCCCTGTGA CACACAATTT ACCTATATAG AAAACCTGTG CATGTACCCC TGAACCTAAA AGTTAATGGT GGGGGGGTGG GGTTAAGCTA

CTTTGTGGTA TAAATCTGAG CATTCATATT AAAATAAAAT ATTTACCTCA TTAGAGTAAT TAACATTTAT TAAGCAAAGA GCCAAGTACC TTACACACAT GATGTTTAAT CTCACAATGA TCTTTAATCT GATAACAACC GTCCATTGTA TGTACATATG TGGAAATTGA GCCTTGGAGA GATTAAATGC ATGGGGCATG CCATTTGACT AGAAACTGGA AGCATCAGGA TTTAAACTCA GTTCTGAATG GTTTTGTAGG CTTTGTTTTT TCCACATTAT AGCATGGCCT GCCATGAAGA ACAGGTCCTT TCTGGTGTTT GTCTTGTTTG GTTTAAGTGA AGCAAATATT TATTTAAATA TTCAAGATAT GCTGTTAAAT TTTTACTCAA AAATTTGAGT ACAGTATGGA TCTTCTGAAG CCAAATAACT CTTATTCAAT GCTTAGTTGA GAAATTTTAT GGAGTAGTTC TCAATTTTTA TGTAGTTCCA CTGCAAAGGT AAGTCTTATG GAAAGATTCA CTGTAATTTT TTTTCCTCAT TTGGACATCA

GCTTTTTCTT TTCCTCAGAC CCGCTGAAAG ATAATTTTTA AAATAAAAAC CTTGTTTTTA TATCAAGTGG GGACATTTTT TCCAAATGAA AACCGTGTAT TCATTTTATA TGATAAAATC AATGTTATTA TTTTTAAAAT TTTGATTTAA AAATCATTAA AAATAAATTT TCAGATATTA CCTGAAATTC TACCATCCAG AGATAATAGT GCTTAAAGAT TTGATATATA GACACACACA CATATATACA TATATATCAT CCTAAACTTC TTTGTATAAA TGTATATAAA GTTTTTAATA AAAACTAGGA GATTAATGCC CTTTGAATGA AAATAAATAC AATGTGTATG CTTTAACATC TTGCCTTTAC TTTATAACAT TTATCACAGC AGTCATGAGA TAATGATTTA CATGGTCATT GTTAGTAAGC TAATAGCTAA GTGCATGAAC TCTGGAGCTA GCCTCCCTGG ATTTTAATCC CAGATCTGTC ACTGACCAGC TGAGCAATAC TAGGTAAATT GCTCTTGTTC CTTAGTTTCT TCATCTGTAA

AATAGAGATA AAAATAATAT CCACCTCATA GGATTGGTGT GAGCATTAAA TGAGCATACG TATGTAGGCC ACTTAACAAC AATGCCTTCA CATACTGAAC ACAAATATAC GAGCTGTTGT CTTATTGGGC TCATGTTTTT CCTACCACTA AGCCGCATGC ATGCAAGGAC CATGTTGGTT TTGTTCCACA TTGCATCCCC AACCTGGTAT ACAGTGTGCA TTCAATAGTT GTTGACTATT ATTACTAGTG GCATTTAACA AATATCTGTT AAATGAGTGA AGAAATACCC ATTTACTGCA AGTGTGTCTA ATATTGATGG CATAATGGGG GAAACTCAAA CTCTGGAGTC AAACAGGTTT TAAAACCTTA TTCCCTCATC CTCAGTTATT GACGTTTTTT TTTTGGCAGG TGTGTGTGTG GGACAACTTA TTGAACTTTT CTGAATTTCC AGCTTCGCAT ATATAAAATA GAGATAGTGA TTCATTCTTG CAATGTATGG ATTTGAGACA ATTGTGTAAG TTTATCAATA AATAGTAGCT ATTTTTGTAT

AAGTATTACA TATAATATCC AGGCCACTGC TTTGCATAAC CCAAAAGGGG CACCATTCAT GCAGAATACA ACATAAATGG TGTCCCTGGA GCAGTGCAGT ATAGGAACCC TGAGGGGACC TACAGTATAC TTTATAGTTC ATAGATTACA AATTATCCCT TTATCAGAGT CTCTCAAGGT TGGATGTATT TGAGGTCCAT AAGAGCAATT TAGGATTAAC AGTAGCTGCA GAAACCATCT GCAGTGATAT TCTCATTTTA AATCCGCGGG AAAGAAGACA GCTATAAACT TGGGACCTGG GTTTAAGCAT TTTAAATGCC AAGTTCACCA TTTTCTAAAA CACAACAAAT ACCCAGTGAG AGAGGGAGAA GGGAAGTAAA TGCCTCTGAA TAAGCAAGTT AATGTCAGTA GTTGTACTGT ATGCATATTG ATGAACAATA GAGGAACCAA TGTCCAATCA GATGAGCAGG ATATTTGGCA ATAACAAGTT GCCTTTGAGG AAAAATGATT TTCTTGGCAA GTTCTTTATC AGCATTACAA AGCT AAAAGC

TACGCTTATC ATCACTTATA CTAGCATACC CTGTTGTGCA AATGCTGTCT GTGTTTGCAT CTGCTATTGT TGATGCCTGG TGCATGAATC AGGACTCCAG CCCACAAGTT TTCCCAGAAC TTTCTTATGG CCATCATCTT TAAGTGTCTG GTGAACAGTC ATAGTTTGGT ACACAAAAGG GTCAACCTGG GGGATGGCTA GGGTTTGACT CAGTCGTTAC ATTTCAATAG AGCAGGAAGG GGAAATGGTG GCCTGTAACC TCAGGGAATT TTGCCAGTTG GTCCACCCCA CTCTCTCTCT CCTGCTCTGA GGAAGTGGCA CAGCCTAGAA CAGCACCACA GGTGAGAGAA ATGCAAAGCG TAACCAGAGA AGCAGACTCT TTGCCAGTAG TAATAGTTCA GGACCACCAC CAGCTTTTAT TAAAATTTTT AATAACACTC AAGTATTGGC AGAAAGAAAT AATCTTGGGT TAACTATAAC TAGAATATTG ACTCTTCCTC TGTGGAAGAA TCAGCCAATC ACATTTGTTT ACATCAGTTC CCCTGAAGAA GAAAAATACA CTGATGTTGC AGCAAGACAA ATTTAAGCTA GATGTAAATA ACTTCCTTTA GCCTGTAATG CTAGGCTAAT TACATATTGG AACTATTTTT TCAGGGAAGA ATTGTGTAGG GTTTCAGGGA AGAATTCTGA AGAAAATATA GAGCTGAAAT GATCTTGCAG CTCACTGAAA CTGCAGGGTT TAGATCCACA CTGATACTCG TTCTATTATC ACTGTAATGA AGGCTGATGG AATAAGTAAA AATGTTTTGT ATTAGTATGT TTTTACACTT ATTTGCAAGG CATAAATAGG TTAGGTTTTG ATCTTAATTT AATTCTAACA

TGTATTGTGC ACAAGCTGTG AGCAGTTTTC AGGAGTTAGG TATCTGGCCA TGACTGATTT TTCAGGAGTT AATCATCTGG TAGAAGGGTC ATACACAATA GGAAGATGTG TGTGACAGGT TGTGATCATT ACTATAATCA CACAGAGAGC TGTAGAATTT TAGGCTGGCA GGGTGGCTCA CGCCTGTAAT CCCAGCACTT TGGGAGGCCA AGGCAGGCGG ATCAAGAGGT CAGGAGATGG AGACCATCCT GGCTAACACG GTGAAACCCC GTCTGTACTA AAAATACAAA AAAAAAAAAA AGCCAGGCGT GGTGGTGGGC GCCTGTAGTC CCAGCTACTT GGGAGGCTGA GGCAGGAGAA TGGCGTGAAC CCGGGAGGTG GAGCTTGCAG TGAGCCGAGA TCGCATCACT GCAATCCAAC CTGGGCGACA GAGGGAGACT CAGTCTCAAA AAAAAAAAAA AAAAAAAGTC ATGTT AGATC CAGAGGGGTA GCAACTGGGG CTGGGCTGTC AGTCAACTCA

GTCAACTCAG TCAACTCTGC TCCCCCACAG GAGATGCCAG TGATGCATTT TCATGGCCAA CATTGTCAGT CAGCATCATT GAATTACTCC TGATTATAGA GACACAGCTG CAAACGATTC CCCATTAAAT ATGATGTTTC TTGCAATGTT TGGAAGGTAC TCCTTTTTAG TAAGGGAAAT CCCCTCTTCT GGCTTGCTGA AAGTTTTTTC TTTCCATTTT AAAAATCGTG AATTCCTTTT TGCAATATTG AGGTGGTTAT ATGGTTTCTC TTCTCTAATC TGTTAATATG GTGATTTAAT GGTTAGAAAT TTTCTAATGT AAATTCCACT CATATTGCAG AAATAAACCT AAACTGAGCA TGAGGCTATA TTTTTTATTT GCTTCTATAT TTGGTTGCTA TACAGTATTA TGTTTAAGAT TTGTTCACAT ATATTTGTGA ATGGGATTGG ACTATTTTTC CTTCTTGCCG ATTTTTATCT GGTTTTTAAA TTAAGGATAT TTTAGACTTA TGAAATATTT GGCAAACAAT CCTTGGCAAG TAATTTTTTG

GGGAATTTGT TTTGGCTATT TTGAGTATTA CCCAATATAT TTTAATTAAG TTATTCTTAA TGTTTTCTTA ATTAAAAAAA TTACCTACTC TAGAGATATT CTTTATGTAC TCCAGATTTT GTCTATTTAT ACCACTTTTC TTTTTTCCTC GATGAGTGTC ATAGATGTTC ATCTATTTTT TTATCTTCTT TGATCTTCTC TTATTCCTTG TTTCTATTAA CTTCTGAAGT TTATTATTTT CTTTTTTCCA CTTCCTTATG GTTTATTCTT TCAATTTTTC TCTAACTTCT TAAGTTGGGT GTTTAATTTT TAGCTTGCTT TGCTTTTTTA GGATAAGCAT TAAAACTACA AATTTTCCTT GTTATTCTTT TGCTGCACCC CAAATTGTTG ATATTTCTAT TGTCTAATTT CTATTCAATT AGAATACTTT AAAGTTTCTT TTTGGTTTTT AAAAACTAAC TTTTTAAATT GACAAATAAA AATTGTGTAT ATTTATTGTG CACAGCATAT GGCTTTGAAA TATATGTACA TTGTGGAATG GCTAAATTTA

GCTTATTAAT GTATGCATTA TCTCACATAC TTATCATTTT TTGTGGTGAG AGCTATGTGA CTTTTGAACT TATGAGTTAT TTAAATATTT TTAAATTATT AAGCATATTG GGATTTTAAG TAATTTACCT TTTTATTATT AACTTATAAC AAGTAGAACA GTTAACCTGT ATGATTCTAC ATCATTGAAA TTTATTGACA TTTGCTTCAT AGTCTATTAT ATGGTCTACT TTTGTTCATG TTACATCTGT AGTAGAATTG GCTAATAGTT GAGTAAAGTA CACATATGTC TATGAAATCA AGTGTAATCC AGAGAAAAAG AGAAATTTAC TGAATATATT GTTCTAGGTG CTATTATATG TTGTCATGTT TAATCCTCAC CACAATTGTA TGAGGCAGCC ATAATTAATT CCACTTTACA CATGAGGAGC CTGAGGGTTA AAAAAAAAGC TAGCTCTACT ATTTGTAAAG AATGAAGCAA AGATACAAAT GAAGGCCCAC ATATCCTATA ACTAGATATT TAAGCATTTT AATTCAAGCT TTAAAACTGC

TAAATAAAAT GTGCTCCAAT TTCTATATTG ACAGACATAC CTTCCTAATG AGCTGGGGTT CGAATTTAGA AATCTTTGAT GCTTCAGAGT CCACACTGAA ATGTGGAGGC ACATAGTGAG TTGGTCCCCA GCCTTCAGTC CACCCACCTT CTCTTTACTA AATCACCTTT CACATACATG TATGAACACC CCAGCCTCCA AGTCCAAACC CTAAACAAAA TGGGACACCC TTGTGCATAC ACAGAGACAC AGCCCATCCT CAGGAAAACC TGGAAAAGTC CATACAAGTT CTGGAAGCAA GCTTGGGACG GTTTCAGTAG TGTGGTCTAT AAGGGAGGCC TCAGAAGACA GGTTTTCTTA ATTCTGTGAA CTTCTCCCAC AGTAGAAAGG GTGCTGGAGG AGGGTCAGAG TGAGGACTTC TAAAGCATGG GTCCTGAGTA GGGGCCACTC TTGCCCAAGT CTAAGAAGGG TACTAGAATA GCACACTACT ACTAGATACT AGAACCCAGA TACAAGCACA GGTCTTCTGA AATTAATAAT AATAATAACT

ATTACCATTA TTATACCAGT AGCTGTCATT TATTTAGTGC TTATTATTTG CCAGTCACTG TTCTAAATTC TTTACATGTA TTATACAACT GCCATATAAC TGCCATATGA GGGATGTACC CTCATTGTCA CCATTTTACC GATGAGAAAA CTGGCATAAA ACGTTTAAGT AACTTGTCCA AGTTACAGAG CTTAGTGAAG CCACAATGTT GCTCAATTTG CTCTCAAACT TCAAAGGGAT GGGAAGGACA CCTAAGTCAT AGAGTCTTTA AGAATCAGAG CTAGAAGGAA TCTTAGATGT TATCTAGTCA GCCTCCTCCC ATTACAGTCC AAGAGAAGAT GGCCCTGAGT TACTTGTAGC TATTTTTGCA TGTGAATTGC AAGTGAATAT ACATTCTACT GAAGATAAAA GATATTTAAA GATATCGCTG GATATAGGAA CAGTGGTTTT AAATCTCTAG GCTTTAACTT TTCTCAGAAC AAGAAATCCT TTTTGGTTTT AATCTATATG CACATCTGTA TTTTTCTCAA TTATCGGGTA GTAAAATATA

ACTTTTCTTC TGTAATATTT TTTAACTTTA ATGAGTGTTC CTCATAATAG AAAAGTTTGG AAACCATTGC TATGGGTATA TACTTTCTAA AGGGATAGTA ATTTCTCTAG AATATTCATT TAATGCTCCA GAAGTAATTA GCACAATTGT GCAAGTCTGT GCATCATCAA CTATACATTC TGCCTGTTTA CTCCAAATCC ACATGAAACT GATTATACAG TCAAAGGCGA GCCCAGTGGA GAGGCATTTT TGGAGACTTC CTGGTACATT GAGACAGGGT CGGCCAGTCT GCGTTAGGGT CTTGGTCAAA ACTGCATTTC TGAAACTAAA CTCAGATTGC TTTCTTTTAA GGGGTCAGAA CTGATTCAAA TCTACATTTT TAAAAGCCTT AGATGTGGGG CTTTTCCTAT TCCCAGTCTC CGCTATTGGT CTTTGTGAAT CCACAGGCAA TTTGGCCACA TCCTTGACTC TCTCTTATAT TAAGAATTAA ACAGCTAAGT TCATGCAGAG GAAATATAAC AAAGGAGGGA CTTTCCTACA AGATCTTTGA

AAAATGGAAC ATTTGCATAA GTCATATTTA GCCAGAACTG TTGTTTTATA TTTTCCTTTC TGAATACTTT GTTACACCTC CTCCCAGCCA ACCCCCCCCC TCCCTGACCC CAACTAGTCA GAGACCAAAG CCTTCACAAT GGTTTACACT TGAACCTTCC TGGCCCCACC CTCATCATCA CGCCTGAATA ATTACATTCA CTGACTGGTC TCCCCTGCTT CCGTTTATCT CCACTCCTAA ACCCTCTGAC ACCTTAATCT TCCCAGAATA CCATTGTGAT CCTGTTCCAC TCTTGCTCAA GTTTTCCCAG AAACTAGAGT ACAAACTTTA TAAGCTTTAG AGTTGAAAGC CACTCTATCT CTTTTTCATC CCCAGGTCTC TGCCAAGGCA GTATAACCTG TCCAACATCT CTAACTTCAA TACCTTTGTC TTAGATACTA GACTCTCCTC CTGGTTTCTA ATTAAACCTG ATCTAGGATC TAATTTTGCC TCTGAATTCT GTTGCCCTTT GCCAAGTGAT CTCTTCCTCC TCTGAGCCGC AGCATCTCTG

AGCTTGCACA CTTAGCATAG CCATAGCACA CACAGCCTTA GCTTGCAGTT CAGGGTGTTT ACCTTCCCTC CCCTTCCAGA TGCTGGATCC CCAGGGATAG GAACTCTGCC CTTATGTGTC CATAGCCCCT GGTAGTATGT CTTGCAGTCG TACATTTTCA GCAAATGTTT AATTGGTTAA TTGAAGACAA CTGTCCCATG CCTTAAGCCT CTCTTTTTGC TAAACATGCC TGTGTCCTTT GTCATTGAAC AACTATTTTG ATCTATTTTC TTCCTGACAT AGGGGTCAGT TCCGAGGATG CTGAAATCAA GAGACATAGC TTATTCTCTC AAAATTGCTT TCAAGAGTGA TTTTGTTGTG AATTGAGAAC TGGCTGCCTA CTTTTGGACT ACCCACTTCA GCAAGAGTGT TTGAAACCAA ATCTATTCTA AGTAATTTTT TATTCCCTTT TCTCTATGGC ATTAGACACA CAGCTCTTTT AAACTACCTT TCGTTATCTA TTAAACAGAC ATTCAGTAAC TCTATAGACA CTGTCTAGCT ATATGAACTT

AGACAAACTA ATATCTCTGA GCTTCAGTTT CTTAAAATTT AAAATGAGGA CAATACCATC TATGGCCGGG GATTAAATGC TATGAGGAAT GTAAACCAGA TGTCAGGTAC CATCTCTCTA AAATCCAGAT AAAATGAATT AAAAATACTG GCCGCAAACC CTCTCTAAGA GTTCTCAAAA TTCTCAGAGA GCTTAATTTT CATGCTCACC ATAGCACCGA TTTTCTTCTA AATATTTTGT TTCTACCAAA ATATTTTGTC CCAATTTTGC CTTTTATGGC TATTTCTTCA TATCCACTTT CCCAAACTAA AGAAGCAGCC CCTTCACCTT AAACTCCTCC TTCAAAGCAA CCTAAATACA GGTCTGGGTT TGTATTCCTA GTGGGATGTT ACAGAGGTTA GTGTGATGCA GAGGAGGAGT CATGCTGTTT AAATCCATAC TAGTCCCCAG AGGCCAGGCT GCTTCTGCCA CCCCTACCCC TCCCGCCACA GAGCTCTTCA GCTTCTCACA TTTCTAGTTC TTCTCTCTCT ACTTTCATTA CCTTCTCTCT

TTTTTTTTTT CTTCTCATGT GCTCACGGGA GCAGAGAAAA TTAACTCCTC TAAGTTTTCT TAACACAGAG TGCCTTAATT ACATATTACT ATTGTTTGAG TTCCTGCCAA CACTACGTCT GTAGGGTCAC ACCTGCTATA TTAGAGGCTT ATCAAAAAAA GATAGCTTTC TCCTAAAAAG GGATTTGGAT GCCTACTAAG ATAACTGGAT GCCAAGATAA GTTTAACCTA ACAAACTTTA TTATTATTAT TATTATTATT ATTAGAGATA GGTACTTATT CTGTCACCCA GACTGCAGTG CAGGGATGCA ATAATAGCTC ACTGCAGCCT CAAAGTCCTG AGTTCATGCA ATCCTTCTGC TTCAGCTCCC TGAGTAGCTA GGACTACAGG CATATGCTAC TCTGCCCAGC TACTTTTAAA AAAATAATTA GGGATGGGGT CTTGTTGTAT TGCCCAGGCT CGTCTCAAAC TTCTGGTTTC AAGCAATCCT CCTGCCTTTT ACCTCCCTAA TTGTTGGAGT TACAGGCATG AGCCACAGCA CTCAACCAAG

ATTTAAAAAC TTTTAAAAGA AATCACATTA CTTACTGTTA TCATCATTAT GGTTACTACC AGTGTTAAAA CAATTGGTAT TGAAAACACC ACTACCAGAT CAAGCTTCAA ACCAAGATGT CAAGTAAATA TTATTGTCAG ACCTCTGAGC CCAAGCCTGC AGGTATACAC CCAGATGGCC TGAAGCAAGT GAAGAATCAC AAAAGAACTG AAAATGGCCG GTTCCTGCCT TAACTGATGA CATTCCACCA TTGTGATTTG TTCCTGCCCC ACCTTGACTG AGGGATTAAC CTTGTGAAAT TCCTTCCCCT GGCTCAGAAG CTCCCCGACT GAGTACCTTG TGACCCCCAC CCCTGCCCAC AAGTGAAAAA CCCCCTTTGA CTGTAATTTT CCACTACCCA CCCAAATCCT ATAAAACAGC CTCACCCCTA TCTCCCTTCG CTGACTCTCT TTTCAGACTC AACCTGCCTG CACCTAGGTG ATTCAAAAGC TTTATTGCTC ACACAAAGCC TGTTTGGTGG TCTCTTCACA CAGACCATGT GACATTTGGT

GCCGTAACTC AGATCGGGGA ACCTCCCTTG GGAGATCAGT CCCCTGTCAT CCTGCTCTTT GCTCCATGAG AAAGATCCAC CTATGACCTC TGGTCCTCAG ACCAACCAGC CCAAGGAACA TCTCACCAAT TTTAAATTGG GTAAGTGGCC TCTTTTTACT CTCTTCTCCA GCCTCTCTCA CTATCCCTCA ACATCTTTCT CCTTTCAATC TTGGCACCAC GCTTCAATCT CTCCCTTCCC TTAATTTCAG TTCCTTTCTT TTTCTGGTAG AGACAGAGGA AACGTGTTCT ATCTGTGAAC CCAAAACTCC AGCACTGGTC ATGGACTTGG AAAGACAGTC TTCCCTTGAT GTTTAATCAC TGCAGGGATG CCTGCCTGAT TATTCACCCA CATTTCAGAG CTGTCTGATC ACTGCAGGGA CGCCTGCCTG GATCCTTCAC CTTAGTGGCA AGTACCACTT TGCCTGGGTG GCAAGCACCA CCTCTCCTGG GGGGCAAGCA CCACCTCTCC TGGGGGGCAA GTACCCCCCA ACCCCTTCTC TCCATGTCTC

CACCCTCTCT TCTCTGGGCT TGCCTCCTTC ACTATGGGCC ACCTTCCACC CTCCATTCCT CCCTTTTCTC CCTTAGCCTG TGTTCTCAAG AACTTAAAAC CTCTTCAACT CACGTCTGAC CTAAAACCTA AATGCCTTAC TTTCTTCTGC AATACCGCTT GACCCCAATA CAAACTCAAC AATGGTTCCA AATAGCCTGA AAACGGCACT TTCAATTTCT CCATCCCACA AGATCTAAAT AATTCTTGTC GTAAAATGGA CAAATGGTCT GAGGTGCCTG ACATCTGGGC ATTCTTTTAC ACGTCGGTCC CTCCCTAGTC TCTGTTCCCA ATGCAACTCA TCCCAAATCC TCCTTCTTTC CCTCCTGCCT GTCCCCTCAG TCCCAACCCC AAGTGTCGCT GAGTCTTTCC AATCTTCCTT TTCTACTGAC CCATCTGACC TCTCCCCTCT TCCCCAGACT GCTCCTCCTC AGGTCGCTCC CCGCCAGGCT GAATCAGGCT CCAATTCTTC CTCAGCGTCG GCTCCTCCAC CCTATAATCC TTCTATCACC

TCCCCTCCTC ACACCTGGTC CAGCTTACAG TTTCATTCTG TGACTAGCCC TCCCCCACCT GCCCAACAAT TTCCTCTTAA AGAGGTGGCT GGAGCTAAAG GCATAGTCAA GGTTAATGCT CCTTTTTCTT TATCCAACCT CTCCCATCTC AGTTAGTATT TAGGCTTTTT TTCATCAAAT ATGAATACCT AGCCCACTCC ATGGCTCATT TGGCAGCAAC TCCTAGACAT TTTACAGCCT TGGACCCAGA GGGGCCAGAA GGTCATCTTA TTCTCAATAT GCATTTTATT ACCCAATCCA CTCCCAACAT TAGAAAAAGC TCCAAAAGTT AGACTCCGGC CCTCAAACCC CACAACAGGA CTTAATTAAC CTTGCCTTCA AAGCGTACAA TAATAGAGTA GAGGCAGCCA AGTAGCAACA TATTTCTGAG TTGCAATTCC TTGCCTCCAC TGTGAGAGAA ACCCCAGCCA CATCTCCAGT ACACAAGAAC TTCAAAATGC CTAAGCCACA GTGGTCAAGC ATTCCTACAG GACCTCCTCC ATCAGGATCT

TGCTTCAAGT GCCAGAAATC TGGCCACTGG GCCAAGGAAT GCCCTCAGCC TGGGATTCCT CCTAAGCCAT GTTCCATCTG TGTGGGACCC CACTGGAAAT CGGACTGTCC AACTTGCCCA GCACCCACTC CCAGAGCCCC TGGAACTCTG GCCCAAGGCT CTCTGACTGA CTCCTTCCCA GATCTTCTTG GCTTAGTGGC TGAAGACTGA TGCTGCCTGA TCGCCTCAGA AGCCTCCTGG ACCATCACAG ATGCTTTTGG TAACTCTTAC AGTGGAGGGT AAGTCCGTCC CCTTCTTAAT CAATGCAGAG GCTACCCACT CCACATTACC TTCTCTTCAA GGTCCTGTTT CCCTTGTCTT CATAAATGTT GTGGGTATTG ATGGCCAGGC TTCTAAACCC CTTAAAACTC CCCAACTCTG GTGCCGATTT AAACAACATT CTTTTATACA CTTCTTTTTA GTTATCCCCA CCTGCCCAGT TCCCTTATTA GGCTGAGACA TTTTAACCAA ATTATTTGCT TCCCTGACTA TTCCTGGACT ACAGCCACAT

CTCATTGCTG CCCTTCTTCC CAACCCAAAA GTGGCAACTC CTTTGCCACT TCCTCTCATA TCCCCCTACC TTAACCCACA GGTATGGGAC ACCTCTACTC CCTCCCTGGC AACAAATCAC ACCCTCATTA CTATCCCATT AAAACCTAAT CACCCTTACC TGGGTCAACG CCAGTATCCC ATCCCACAAC AGGCTTTAAA GGGATTAAAG CCTGTTATCA CTTGCCTGTT ACAACATGTC CTTTTAAAGC CTGTAAACTC TCCTTACAAT TCCCCCATTT TACCTGTCCA AAAACTGGAC ATGCCTTACA GGTTAGTTCA GGATCTGTGC CTTATCAACC AAATTGTCTT GCCTATCCAC GCCATGGTGC CAAACCCATA TACTCTCCTA TCCTCAATAC CTCCCTCCAA AACCCCTCCA TAACCCTTAT TCTGTTCTGG ATCTCAAAAC ATGCTTTCTT TACTATTCAT TTGCACCCTT CATCCCAGCC TCTCTTCACT TTCACTTGGA CTGACCCTGA CACCCATCAG CCTCAGCAAC TTACCTGGGC

TGTACTGCCG CAAGGCTTCA TGGACAGCCC CCATTACCTC AGTCAACCCA AATTTCTTCT TCATCCATTA CCTATCCAGG CATAGTTCTT CATGAAAACA CACGTGCTCT CCCTGCTGAT CATGTCCAGC TAATCTCCCC AACCCCAGGA CTGGCAAATT GACTTTACTC ACATGCCCCA AATCAGGACA CTAAAGTACC TCTTGGTCTG GGTAGACACT TTCACTGGAT AGGTAGATGC CTTTCCCACA GGGCCTAAGA AGGCCACCGT GGTCATTTCT TCCCTTCTGT CAGACATAAT TCCTTGGTTT GGCCTTCCCA CCTCTATACA GTCTGATAAT GGACAAGCCT TTACTAGTCA AAGCACGCAA GCAGTTTCTC AGGCTCTTGG TATTCAGTGA AACCTTCATA CCCCTTACCG TCCTCAATCC TTAGGAAAGG TAGAACTGAT TAATGGTCTT TTAAAAACAC ACCTCACCAA GCTCAGCCTC CAACTTAAAA AGGACTGGAC AGTACTTTTA CCACTTGCCA TTCTCAGAAT TCGGGCCTGT

CCTCGAAATG CTACAAGGTA CAGCCCATTT AAGATTCTGT ATGGACGCTC CTTTTTATTA GGCCCCAGTC TCATTCCAGA CACCAGCCCA ACTTGAACTG TGCCCCAAAA ACTTGTCATC CCTACAATCT TCTGTCTAGT CATACTCCTA TTCACCATTC TCAACTACTT GTAAATGCCC TGCCCTTTTT TACAGTGCTG ATTTATACTT TTCCTCCAAA CCATCATAAC TGATATCTCC TGGTTTTACC TCAAACCGCC ACCCTTAAGT CTCTCTTAAA GTGGATAGAA GATCTTCAGT GACAAGGTAC ACTCCAATAC TTTCACCCTA ATAAAGCCCT ATTCTTTACT TTTATATTCA CTCTTATTCT TGTTCCCATT CTTATGCCAC TCTCTACCTC TCCCCAGCTA TCTCCACCAC ACTATCAATC TCACTCACTC TCTCCTAGCC ATTTCTAATC CTTCTTTAAC AAACAATTGC TGGCTTTACA ATTTCTCTTT CCTCCAAAAT CACCGAGTCC TCAATTTACT CACTGCTAAA AAAGGGGACT CTGCATATTT TTAAATGAAG AGTGTTGTTT TTACCTAAAT CAATCTGGCC TGGTATATGA CAACATAAAA AAAACTCAAG GATAGAGCCA AAAACCTTGC CAACCAAGCA AGTAATTATG CTGAACCCCC TTGGGCACTC TAATTAGATG TCCTGGGTTC TCCCGATTCT TAATCCTTTA ATACCTGTTT TTCTCCTTCT CTTATGCAGA CCTTGTGTCT TCCATTTAGT TTCTCAATTC ATACAAAACC GTATCCAGGC CATCACCAAT CATTCTATAC GACAAATGTT TTAAGGGAGG AGACCACCCC TCATATTGTC TTATGCCCAA TTTCTGCCTC CAAAGAAAGA AGTAAAAATG AAAAGGCAGA AATGAAATCC ACAGGCAGAC AGCCTGATGC CACACCCTGG GCCTGGTGGT TAAGATCAAC CCCTGACCTA

ATCAGTTATG TTATCTATAG ATTACAGACA TTGTATGGAA AAGCACTGTG AAAATCCCTG TCTTGTTCTG TTCCTCTAAT TACCAGTACA CGCAGCCCCT AGTCATGTAC CCCCTGCTTG CTCCCCCTGC TTGCTCAATC AGTCATGACC CTCTCACGCA GACCCCCTTA GAGTTGTAAG CCCTTAAGAG GAAAAGGAAT TGTTCACTCG GAGAGCTCGG TTTTTGAGAC ATGAGTCTTG CCAATGCTCC CAGCTGAATA AAGCCCTTCC TTCTTTAACT CAGTGTCTGA GGGGTTTTGT CTGTGTCTTG TCCTGCTACA GTTTCATCTA ACAACCCCAT AATATCACCC CTTACCACAA AATCTTCCTT CAGCTTAATC TCTCCCACTC TAGGTTCTCA CGCCACCCCT AATCCTGCTC GAAGCAGCCC TGAGAAACAT CGCCCGTTAT CTCTCCACAC CACCCCCAAA AATTTTCACT GCCCCAACAC TTTACCACTA TTTCGTTTTA TTTTTCTTAT TAATATAAGA AGATAGAAAT GTCAGGCCTC

TGAGCCCAAG CCTGCACGTA TACATCCACA TGGCCTGAAG CAAGTGAAGA ATCACAAAAG AAGTGAAAAT GGCTGGTTCC TGCCTTAACT GATGATATTC CACCATTGTG ATTTGTTCCT GCGCCACCTT GACTGAGGGA TTAACCTTGT GAAATTCCTT CCCCTGGCTC AGAAGCTCCC CCACTGAGCA CCTTGTGACC CCCACCCCTA CCCACAAGTG AAAAACCCCC TTTGACTGTA ATTTTCCACT ACCCACCCAA ATCCTATAAA ACAGCCCCAC CCCATCTCCC TTTGCTGACT CTATTTTTGG ACTCAGCCCA CCTGCACCCA GGTGATTCAA AAGCTTCATT GCTCACACAA AGCCTGTTTG GTGGTCTCTT CACACCGACA CGCGTGATAA TTATTATATT ACTTTTAACT AAAACCCTTT CAGAGTCTCG CAGGGAAGGC TGTATATATC TCATAAAATG TTGGGGCCCA CTGGATCAGA CAAGGCCACA AAGGCCAAAG GGAAGTAAAG ATCTCATTAT TTCTCCTAAT AATTTCCCTG

TCCTTTGTCA TAAATGGTGG GTAGGCTGTT ATGGTGATGG CAGATTTTCT TTCCATAAAA TGTCCATAAT AGGACATTTG AACAGAAGGG AAAAATCAAA TTGCTGAAGT TGAAAGAGGG CAATGCAAAG AACTTTGGAG AAAGAACTGT ACAGAGAAGT CAACTGGCAG ATGGGAGGAA GTTTAAGGGG AAAAATATAG ATGTCTAAAG AATACATTTA TTCATTTTCC ACAGTGCAAT TTGGACAAGA AGCCTCTTTC TTGCTTCTTT CTATTCTCAT TAAATCATTA GAGCTCAAGC AATCCTTCTG CCTCAGCTTC CCGACTAGCT AGGACTACAG GTATGTGCTA CTATGCCCAG CTAATTTTTT AAAAATTAGA TTTTAATTTG GTGAACTATT TCTGTAGGAA ACTACAATAA TACAGCCCAG GCACATTGAT CTTGGGTGAA CAAATCAGAA GGAATGAATA ATTCTGTGTT CCTGGGACTC TGACAATTTC ATGAACTTGG TACTCTGAGT AAAGCATAGG AGGAGTTATT

TCATAAAATG TGGAGCACAA TCATGTGACA AAGATAATGG GATCCCCATT TCATAAATAA ATCTGAAGTT CAGAGAGAGT AACAACTGGC CAGGGTCACA TCACGGAGAC AGAGGCAGGG TTCCCACTGA TGCCTCTGAC TCCCTGTCCC AGGCCCTTCC TCCTCCCGCA AGCAGAAGTG CAGGGGGCAG AGCTGACCCT GTGCAGTGAA AATCTGAGGG CTGAGTTCCT ATTGGAACAC AAGTGAAAGA CTTCCTGGCT TCTAATCTCA GGATAAGGAC TCAGAGCTCC ATCTGTTCCA GCCTTAGGAT AAGAACCAGA ATCTTACACC ATGAAAGCAT GAAAGGTAAG ATTTGAGTGA GGAAAAAAAA AAAAAAAGTC TGTGTTTCAG ATTCAGTTCA CAAAGCAGTT TCATACTTAA GGTACCATCA CAATAACCCT GTGGGGTAAG CAAGGCAAAT TTCATTCTTG TTTTATGGGC ATAGGAAGTA AGTCTCAGGG AGGTTAAGAC CAAGGTTTCT GGAGAATTTT ATATTATGAA TCTTGATTTA

TGGGATTACT ATTATGTAAT TCCTAAGATC ATATAGGAAT CCTAGAGCTT GAATATAGAA CTTTATTTTT AAATCTATAT ACATCATAAT TACAAGGAGT AGTGTCCATT TGGGTTCCTT GGCCCTGATG TGTTAGTGGA ATAAACATTT TTGTCAGGGT TGCCATGTGT GTCTGTGCAC GTGTGCACTG TACACCTCCA GGGGATGTAC CCTAAACCAC ATGAATGTGA TTTGCACATC CAAGATTTAC AGTGTACTAT AGGGAGAATC TTTTGCAACA GCTTTTGCTA TAATACAGAA TGTGAGATGT CTTTGAGAAA GAAAAGTGTA ATCATTACCA AAAAATTATT CTCATAATGT GTGCAAATTT GTATGAAATC TATATTGGCC ATGGGACAAG GAGGTATTTC CAGCTAGCTT CTGAAAGGGC TCTATTCTCT CATAAGAATT CAGCTGTTGA CATTAGGTGA TATCTGCCCA GGTCATCAGA TGCCATAGAG AAAGAGGGTT TGCTGAAACT TATATCAGCA GTGCACTGTA TGCTCTTTCT

GATTTATTTG AACATTCATT TATTGAGTGT CAAGTAATGC ACTAGATACT CCAGGGATCT GACACAAACT CTGCCCTGAA GGAGCATGTA ATCTCACTGG GGAGAAAACA AAACATATGA TAATTTCAAA ATAACAAACT AGGCAAACTA GTTAACACTT AAAAAGCAGG CTTTATTCAA ATGCAAAATT GCATGTTACA GGGTAACCTT TCAGTAAGAA GCCAGGAAGA GGAGCTCATC ATGGGTTGGA TTAGTAAAGG ACTAGTTATA AAAGAAGTGG TGGGGTTGAG GGAGGCCTGA GATGAAATTT AAAGAATATG TAGAATCTAG GTAAGTGGAT AAAAGGTCTG GGGGCAGGGG AAAGGAGAGC ATTTCATTGT GAATCAAGGA ATTTCTCCAC CTGTTTTAAC TCTTCCATAT GACATCAAAG AGATGTCACT TGCAGCTAGC ATTTCAGTGA TGTTTTCTTA CTAATAATAT CGTGATAAAA GAAACATTGA CTATAAGAAA TAGGAATGGG TCTCATAAAA GGAAACAGCA

AAACCCCCAA ACTAAAAAAC AGCGCAGGCT ATTTCTCTCT TCTCTCCTTT TGCTTGGCAC TCATGAGATG CTAGGTGTGG AAGTCAGCCA ACTGAAAAAG AGAGGTGGCT GAAGAAGGTG GGGAGGCTGA AGCCAGTTAA ATAGGATGGT CCAATTCACA GACGGCGAGG CTACAGTGCA AATAGGACTC TTTCAACTTG AGCAGGACCC CATTACTTCA CTGGAGTTAG AAAGAAAGGA GAGCGTAGAC TTTTTGAACT TTCTATAAGA GTGTACCTCC ACAGTATACA GAAGACGACG TGAAATTTGA TCTGCAAGAA AACTGAGTCC ATATTCACAT ATGTATCAAA TTTGCACTTC ATTTAGAAGT GTCTGTCATC AAGTACAGCA CTGAATTGAA ACTGAAAACA AGAGTCAAGA AAGAGCAAAG TCAGCCATCT TTATATTCCA CATGAATCCT TTCCCTTTAT GGTCTTATTT GTTTCTCCTC AGAAAAGACA AAAAGCTGAG CTGTATAAAC ACCTGTGGGC TGGGGGTTGA GGGATAAATG

AGGGGCGAAA TGGAAGCTGA AGGAACTGTT GGTCAGGTAG AAATCTTCCC AGATGCACTG AAGGAAACAC ACTTCATGTT TGACGTAGGA GGTGCCACCA CACAAAACGT TTCATGGAAG GATTTAAAGG ATCTCATGAT TTTTAGTATT CCAAGAATTT TCTTTCACCA AGGGCGATTT AATATGGGTC ATTCATACTG AAAGAAAAAC AAAAGATAAT AAGAGTTTAA AAATTGCAAA ACTTGGAGTG TTAGTAGTAA AGGTAAATAT TCATTAGAGA TGAGAAGAGG AGCAAGGAAA TGCTTTCAGC TGGAAATCTC AGACAAGAGG CCAGGCTTTA GGAACCTCTG AAGATGAACA AATGTAAGCA AACCCTAGTA GCAGCACTTC TCAGATTTTC ATGTGCTTAC CACTCAGAGA TGGTGTTAAA ATGCAGACTC TGATTCAGTA GGTCTGAGTG GAGCCTGAGA TTCTGCACCC CTAACAAGCT CTTTAGTGAT GCTTATGCCA CTGGCGCACA GACCCCACTT GGAGAAATTT

TTGTGGTGCA TACGGTCTTT GTCTCCAGAT CTAATGAGTC TGAAGGACAG TGTAGATTGA TTTTTTAAAT TTATGTTTAT TTTAATTTAA TTTAATTTAA TTTATTTATT TATTTATTTT TGAGATGGAG TCTCACTCTG TTGCCCAGTC CGGAGTGCAG TGGCACGGAG GCAGCTCATG CAACCACGGC CTCCTGGGTT CAAGCGATTC TTCCGCCTCA ACTTCCTGAG TAGCTGGGAA TACAGGCACG TGCCAGCACA CCCAGCTAAT TTTTGTATTT TTAGTAGAGA TGGGGTTTCA CCACATTGGC CAAGCTAATC TCAAACTCCT GACCTCATGA TCCACCTGCC ACGGCCTCCG AAAGTGCTGG GATTACAGGC GTGAGCCACC GAGCCCAGCT GTAGATTGAT TTTGAGCAGT GGAAAGTCAA GGAATTAGAA GGCATGCTTA AATGGAAAGT GAAATTGGAG AAAATTTAAA CTCATGAAAT AGTGGTGGTT ATAAACTCGT GATAAATTAT ATCCTGGGAT ATAATTTAAT GAGATGGTAA

CACATTTAGT TTAAAGAAAT AAGTGACACT TTTTTTGTGT GACACAACTG TCTTATTCTT GGAAAGGACA AGGAGAGAAT GAAATATGGT ATGTCTTCAC AGCACCTTTC AAAGGGAGAA CCAGATTCTG AGGAGCTGGT CTCATGATGA ACTGTCAGGG TAAACCACAG TTCAGCAGCT GCAAATGTGC TTGCCAAAAT AGAGACAAAA AAATGTTTCT GAAAACAAAA TTTCACATAT GCCCTCCTCT GAGGTTGGCA TCATATCTTC CTGTGTATCT TGGGTGTAGC TTCTATCCTG CCAGAATTTA GACAGTAGAA ACCAAATGAG GTGATAAACA GAGTCATTTT GCAGAAGAGT CAAAATAACC CAGCAAGAAA TGAAACCACA AATGCCCAAG GAGTCATTCA TTCACCATTC AAAAGCTAAT AGAAATGAAC ACAAACTACT ATGAAAATTC ACCCAAGAAC TTAAAAAAAA AAAAAAAGGC TCATGGTGTT TAGTGTGATA GTATTCATTT TACCTTTGAC TTGTTCTAAA AACACACCAT

ACTTCTACCC CACCCTTCCT CAGTGCCGTC ACACAATGGT TTCAGTGTGA AAAAAAAAAC CACGTTACTG GAAAAGGAGG GTGCCTGGGA CTTGCCACTC TAAGCTGGTA GTCAAGGGTC TTGAGTTCTA AAAGCATACG CGTTAAGAGC ATGATTCCTG GATCCAAATG AGTATGGATC TCAGCATTGC CATTTATTGT GACCTCAGGC TATTTTATTT CTCTGTGCCT GTTTCTTTAT CAGTAATGAA GATGTTCATA GACCCTTCTC CCACAGACTT AAAGGCATAT TTCATGATTT AAGACATGTA AACCATTCAT AACAGTATAC AACATGGAAT TAATATTTGA TAAAGGTTTA TGATTATTGT AACTAACTCT GTCACTTGCT CAAGGCCTAT AGAAAACTTA CTTAATTAGT TCAACTACAA AAAGAGTTTG AATGTGATAT CCACCAAGAT CATATTCAGA CCTAGAATTC TGTGATTCTT ATGAATTAAT ACAGCCTTGG TCAATAAATG AGAGCTGGGC AAATAATTCT TCTTTGCTAG

GCCTTTCTAG ACCATCTGGT GAAGCATTCA AGACTTATGT TATTGGGGCC AGCCTTCCTT TCCAACTTCA ACTCCACAAC TCCTCAATAA GCCATGGGCT CAAGAAAGTT CTGCTCAGTG GCCCCTGAAA AATGCTTTCA TAGTCTCACT ACCATACCAC TGCTTACACA ATTTCCTTCC TACAGACTGC CTTCCTTTCC TGCTTTTCTC CATATACCTA AATCCTATCT ATTCTTCATA AGCAACCTTC TTTATAACAT TTTCTATAAC CACCAAGCCA AATGACCTTT TCCTTCTTAA ATATAGCACC CATTGGCCAT TACCATGCTC TGCCTTGTAT TTTTCTGATT TTTTTCTTTC TATATTCCTG TCTTAACTCC CCAGCTAGGT AATAATTTTC CTGAAATCAG GGACCAGGCT GACTCCTCTT GCTGTCTCAA GAAAGCTTAG CAGTTTCCAA CACAAAAATG TTCAATAAAC AACTATTAAT TGACTGATTA TAAAAAATCA GTGAACCATT AAACTTAATA TAGCAATTTG CTTAGCATGG

TAATTAGCTT TTTGCTAATA TTCTTCCAGC CAGTCTCTCC TCCTGTGCCT CAAGGACATC TTAAAAAAAA AAAATCTAGT TGATCTGCTT CCATCTAGTG GCAATTAAAA CAGGTGGTTC CGGTAGCCAG AAAACAGCTC TGGGTAGATT GTGCCAGAAA ATACTTTCAC TCAGTAGGTG CGAGTTTGAA AGAAATCTTC ACATCTGTGG GTTTCCTGCC ACAGACATAG GGAGACCAGC CCAGAGAAAG AAGCCTTTCC TCACTAGACT CCATTTGCAC TAGTAAAGAG AAGACAGAGT AATTAAAAAG AATAAAAAGA ACCTCCACTG ATCGTACATC CTCATCCAGT TACCCCTGCC CCACTTCTCC TTCACAGCCA AACATTTTAA AAGAGATGAC TGCTTGTTCT GTCTCTACTT TCTCATCCTC AGTAATGCTC AATGCTTGGC CGTCTGACCT CTGTCTTGAT GTCTGCACTG CAAATAGTCT CCCCACTGAC ACCCTTGTTG CATCCAGGGG ATACTTACTG GTTCTCTTGG CAATGTTTGA

AACCGTTCCC CTTTCTTTGT TTCCTTGGCA TTCATTACCC CACACTCTTT CTCCTCTTCC TTCTCCCTGC CTGGCAACAT CTTTTCATTT CTCTTTCCCT TAGGTGACTT ATTAGATAAT GATGTTCCTC TGGCTCCCAT ACTCTCTCCC AGGTCCTCTT CCATTCTTAA AGCACTCACA CCCTCCCTGG ATGATAGTAC CCACTCCTGA GATGGCAGTT ACCTCCTGAA ATGTGAGGGA CCCAAATCCA CTTCTCCTGC CATAGCCTCT GTGCTTTGGA TAGGTCCAAT GAGCCACAGT GAATGATGTG CATACACCCA AAGCTCAGTA CAAAACTGAA CCCATGATCT TTACCTCCAA AACCTCTCAT TCTTTTATGT TCCCTTCTCA GAAGTAAACA GGACTACCAT CCGCCAGTTT CCAGGTGAGA AAGATGATAA TTTGATTCTT CTCTCTCACT TTTAGCCAAT TAACAGACAC ATTCAGTTAA TATCACCTCC TCTTATTTCA TGAACCCATT CTTACTACTA GTTCCCTAGA CAGGCGCCAT

CGGTTTTAAT CTAATAACTG CAAATGCCTC CAAAACAAGT CTCTTTGAAT CCAGGCTCAC CTGTCTCCCA CACTTGCCAT ACTGCTCTGC AGGGTGACCT TATAAGATGC CAGAGGTAAG GCTACTCACT GTTTAAACCC CTTTAGTGAT ATCCCAAAAG ACCTCAAGAT AAAGCCCATA TCACATGGCT TATACATTAG TTTATGATCT GGCTTCTGGT GCCTCATTTT TCCCCACTTT TTCCTTTGCA TTCTAAGCAA TGGCCCATAC TAAGTTTGTG ATTGGTAGGA TGGTTGCCCA AACCAGCATC CAATCCCTTC AGAAATCATC TCACTTCATT TCTAGCATTT TAAAGGAAGC TCAGTTGTCC AGCTGGGTAC TGAATATGTC ACCAAAGTCC TCCTTTCATA GTTTATTTTA CTTAAACTCT CCTTCCTAAA ATTCCAGAGC AAGTCACTAA ACCCTAGATA CTGAGAAATA TTTTTCCATC TTCATTTCTG CCAGGTGGGC CATCAACTTT CACATGTCTG CATCTCCTCC CACTGTGCTA

TTTCTCCAGT AGAAGAAATT TGAGCTTCAA GACCAAACTG AAAAATACTT GCCTCCTTGG GGAAGCTGTA GGTAGAATTC ATGCTCCCTA TCTTTCCCAC ATTTCTGAAG GACAATGCCT GTTAGAGCAA TTGAATGCAA ATAGTCAATT GAATAAGCAT TTATTCATTT CTCAATAAGT GCTTGTTCAA TTGAATATTT CTTAAATAAT ATATTTAAGA ACAAGAAGAA CACACCACAA TGTTTTTAAC CCTCAGAAAA AATTCTGAGG TAATCAGAAA AATCTCCCTT TACATAAACT GCCCTTTTCT AATAGGGATT ACTTGTTCGT TCATTCATTC ATTCAGCTCC ACTAGCACCA AAAAGCACAG CTCTGAAAGG AAGCTAGTAG ATTTATCACC TTATCTGGTC ATTTGGATGA GGACCCCAGG TAAATAAACT ACTATGGGGT TAATGTGTCT AGCTAGAGCA GGAAGTAACT TAAGGAAGTA GAGAATGAAT CAGCAGATGT GGAAACTCCT CGCCACTAAT AAAACTTACC TTCTCTTGGA

TTTCTTGCCT GAAAATAGAA AATAGAGAAA AGGCATTAGC AAAAATTAGA CAATTTAAAG TTTTTCAAGT AAGGGAGAAG GAAGACTCCC ACTCTCAAAA CTGTCTTTTG AAGTATATTA GGTATTTGTT AGGTGGACCC TATCTGTGTC AAAGGAGATT TGAGGAACTG GCTTAATAAA CAGTGGTAGA CACTAATACA GAACAGACAT GTTGATGCAG ATGCCTCCTG AGGTTCCATT CCATTCTCCG TGCTACTCAA GAAGACAGAA TTGCTAAATT GCCTGGTGGC AAGACCCAAT ATGTCCATTC AAGTGTTTAT CCCTTCCCAA TCTGCCATCT CATCCTACCT GCAGATTCTT CCCTTGAGGG ACAGCTGCTA ATACTGTAAA ACTATGTGCC ATTACAGCTC ACAGCATCAT CTCTATGAGA ATCCACAAGA GAATTTCACT TTGGTCTTGT TGGTAGGAAT TGTGCAGCCT CATCTGAGTA ACTAATGTGT TTTTATCTTA CAAACACAAG GAATATCACA TGGTTCTCCT TTGACTGGCT

GTAAGGAAAC TCAGAGCTAG ATCTGAGACC CTCTCCTACC AAGTATATAA AACTTTGTGA CATACATTTT TGTGCCATAA CTTCAACCTT GGTTCCAAAT GATTTTTGTA CCCTAAGTTT AAATTTGGCT TTCTTTTTTT TTTTTTTGTA CTCAATAAAA CATCAAGCTC ATTTATTATT GCGAAGAGCG AAACAACAAA GCTTCCACAG CGTGGAAGGG GACCCGAGTG GGTTGCCCAA ATTGGCTTCT TTTTCTTACT TTTTAATTAA TTTTAATTTG CTATACTGAA CACATTTTGT ACTGTTCTCA CATTCTTTTT GAAAAAAGCA GAATATAAAT AAGTAGATAA CTTAAAAAAA ACTCTTTGAG CAGAAAGAAT CATTTGGGAG GCAATATATT TCAGTGGCTG TAAAGTGGCA TTCTAGAATC ATCCTACCCA GGTGAAAGCC CTATTTTGCC ACCTGTAGTG TAGTGTGTAT TTGAACAGCT ACTTTCTTTT CTAAACTACA ATTTCTTCAT CTGTTAAAGA GGCATAATAA TTGTATCATC

CTCATTGGGT TGATAAAATA AAATATTTCC AAGTATTTAG TTCAGGTCCT AGCACGTAGA CAGTGTTGCA TTACTGTTTT AATCCTTTAA AGTATTAAAG ACTACTATTT GAAATCTTTT CTTCTAAAAT TCAGCCTGCT GATGACCAAG TGCACTTGAG CAGGGGGAAT CAAATCTGAA TTAATTTCAG ATTCTGGTTA GCTTCACATA AATATTTTTT TTAGGGATGA TGAACCTAAC AGCAATAGAT GAGTAAGAAT CTGTTCCTAC TGAGAGAGTT TCATTTTGAA GAAAAAGGAA CTAAGGGGGC ATGTGTTCAG TTTCATGCCC TGGTCTAACC CTGTGTGTTG GTTCTGGTGG GAAATTCTTC CAACCGAGGA AAAAACCAGT TCACAAATCT GAAGACCAGT GATTTTAGAA GATGTATCTG GACTGGAGTC TAATCTCTGA CTCTGGGTCC TGCTGATATG GTATTTTTGA GATTTGGCCT AAAACATCAT TGCCCTGGTT TCCTTATTTA CCAAACAGGG CCAATGGTAG TGACTAATCA GAAAATGATA ATGCCTGGTG CACAAAATGT GTCTAGATGA GCCCATGCAC AAGGAGACAT GTTTCTGGAA CTGTTCCTTA TTCCTTTCCT AAAAGAAAGG AGGGAAAGTC TCCATACTAA GACTACTAGG GCAGGGGACA AAGTGCTAGA GTCAGAAGAT TCATCTGAGG ACAGAAGAAT AGGGGTGAAG GCTCTAGTCA CTTCATTGGC TACCATGCTC TAAATAGTTA CCTGTGCCCT TTTTCTAACT ATTAGAACCC AAAAAGCCTA TAAATTCTCT CTCTCTCTCT CTCTCTCTCT GTGTATATAT ATACATATAC ACACACACAT AGACACACAC ACACACCTAA ACACACACAT AGAGATTTAT GACTTTTTAC TTTTATCCTT GTAAATGCCA TTAACTATAT TTTGTCTTAG ATTTAGCCTG GGAATGTAGC

CATTATTTCT ACCATTGCCT CCATAGGAAA AATACTCTTC ATGTTTTAAA GGACCAACCT ACAACTAAAA TCTTTGGAAA GCAGAATCAT TTGTAAGTTG GTGAAAATGG AAGATGTTGT TTTATAAATG AAGACTTTTT TTTTTTTTTT TTTTGAGACA GGGCCTCACT CTGTTGTGGA GTGCAGTGGT GCTGTCATGG CTTACTGCAG CCTTGACCTC CTGGGTTCAA GTGATCCTCC CACCTCAGTC TCCTGGGTAG CTGGGACTAC ATGTGCATGC TACCATGCCT GACTAATTTT TTGTATTTTT GTAGAGATGT GGTTTCGCCA TGTTGCCCAG GCTGGTCTTG AACTCGTGGG CTCAAGTAAT CCTCCTGCCT CAGCCTCCAA AAGTGCTGGG ATTAGAGGTG ACAGCCAAGG TGCCTGGCCC ACAGATGAAG ACTATTTAAT GTTATCTTAA AGATACCCTA AGCTTCCTAC CAAGCCAGTG ATCTTTTGGG GCTTCTGTTT TCTTTGTTGG CATAACTGTA ACTAGCCTAA CTGCCCGTTA

TCTGTTTCCT GTTTGCCCCA CACTGATTCC CACAGCAGTT TTCAAGTTAT CGGTTTGAGA TCTTGTACAG AAATGACTCC AAGGTAAAAA ATTTAAAAAC AACCCCTCTA ATTTTTTTAC CCTTGCTTAT AAAACAGCCT TAGCCAGCTA ACCCCTCACT ACATGCAAAT GAGTTTGATT CTATTCTTTT GATTCTACAA ACACTTATTA AAAGATTTTA GAATTCGGAA ATAAATAGCT TCCTTATTAA GGTGACTTAC AGCCCCAAAG TCCTTAAAAT TATTTAGACA ATAGCCACCT TATCCCAGGG GGCAGTGTGT AATAACCCAC CCTGTTCTCT ATCCGTCAGT TCTGCCATCA TCGCCCAAGG TAGGAAGAAA GACAGGACAA CCGGGGTCAA GATTTGAAGT CTCAATGGAA AGAATAATCA GTGGTTGGAG AAAACTGTCA TTCTTCTTTT GCCTTAATGC AGTACTTGAT ACTTATACTT AGTACTGTAT AGTACTTAGT ACTGTATAAT ACTATAAGAT AGTGAGATTC AATCAGCACA

GAATTTCTAA TAGCAAGGGC AGAGACATTT TAACTGCTCA GTGCTCTCAG GTTATACATA GCTAATGAAG TTCTTGCATA TCAACAATCC CCACCCCCCT CACACACTTT GTCTTTCTGG ATTGGTTAGA AAACTTACCT AGCGCCCACT ATTCTCAAAT TTAAATGAAA GATAAGATCA GAGTGGCACG CAATTAGGGA CTGATAAATA ATATTTTTGT AATTGCCAGT GTAAATGGAC AGGGGGCAAC CTTTACATAC CATATTCAGT GAACAGAATA CGTACTAACT AATTTGATGG AAGGAAAATT AAAATGACAA TCAACTGAGC CCACAGAAAG GCAACACAGA GCAGTTGGTT AGCAATTGTT TCGAGATCAT CCCTGAACTT GAAACAGGTA TATCTTTTTT χ_ττχχ_ττχχχ XXGAGACAGA GTCTCACTCT GTCACCAGGC TGGAGTGCAA TGGTGCGGTC TCAGCTCACT GCAACCTCCG CCTCCCGGGT TCAAGTGATT CTTCTGTCTC AGCCTCCCGA GTAGCTGGGA TTACAGGTGC

CCGCCACCAC GCCTGGCTAA TTTTTGTATT TTTAGTAGAG ACAGGGTTTC ACCATGTTGG CCAGGCTGGT CTTGAACTGC TGAGCTCATG ATCCGCCCGC CTCGGCCTCC CAAAGTGCTG GGATTACAGG CATGAGCCAC CACACCTGGC CAAAACAGGT ATATCTTAAA AGCTGCCCAA TGTCCATGAA TGTTACAGCC TTGAATGGTT CTTCCAGGTG AGTTTGGCCA AATGTGGCAC CATACACCCA AGGCCTGCTG CAGGCTAGTG GGTTGCTCAC ACTTTAAAGC TGAGACACAC TCATGCCTTA AGGTAAAGGG AGTGATAATC TGGGCAGCAG ATGTTAACTT CTCAAGGCAG TCCTCCTTCT CTTTTCCTCT CCAGTGACGG ATGGTTGGAA AGCATATATG GTGCATTTGG TTAGAGCTGT GGCCTTGGTG AATAGATACT TGGGAGAATA CATGGGAATT TCTCCCAGGG TTAATGCAAT GCCCATGTGT TGGGAACCAG GTGACTCTTG AAGAGGTCAG GTATTTGGGA GCAGTGCCTT

GAAACCTTAG TGGACATTAG ACCCACTTCC TAGTGGAATT GTAGCATTGA AATCCAAGGC ATGTAGGCTC TTAGAGGACA GAGATAGTGT GTCATTTTTT CAGAATTAAT TAAGAGCAGG CCAGGCGTGG TGGCTCACAC CTGTAATCCA AGCCCTTTGG GAGGCCAAGG CAGGCAGATC ACGAGGTCAG GAGATCGAGA CCACTCTGGC TAACACAGTG AAACCCCGTG TCTACTAAAA ATACAAAAAA TTAGCTGGGC ATGGTGGCAC GCTCCTGTAG TCCCAGCTAC TTGGGAGGCT GAGGTGGGAG AATAGCTTGA ACCCAGAAGG CGGAGGTTGC AGTGAGCTGA AATTGCACCA CTGCACTCTA GCCTGGTGAC AGAGTGAGGC TCTGTCTCAA AAAAAAAAAA GTATTAAAGA ATTACATAAG AGCAAAGAAC CATTAGAATA TCTCACTTAG TTGTTATCAG CCTAGCAAGC TGCCTTGAAG GTAATAGACA TTTTTAAAAG TTTATCAGAT GAAAAGCGAA AATCAGCCAA

CCTGTTTTAA TGAAGGTGTG TCCTGGGCTG ATTTACATGT CTCCAGGGAC TGATGGCTCT AGAATGTAAA GCTTGGCATC CTGCTTGTGT TGAATCTATC ACATTTAATT TCCTGTGGGT TTCTTTTTTT TTTCTTTTTC ACTTTAAAGT TGTGTTCTTT TCATGTGAAG TTAAACTCAC ATACCTTTTT TTAATCTCCT TGCCAGCCAA ATGATAAATG CCAACCCAGA GAATGCAGTA ACCATGACTG CCACTGGAAT GAAGAGGGGG TTATAATCAC CCTCCTTAAT CATTGAGAAA CTTTTGTCCA ATTCTGAAAG AGAAATCAGT AAGGCACATA GCATGAGACC ACCAGCATTA TTTCCTTAGT CTATCTCATG ATATTTGACT TTTTTCCTCC TTACATCTCC CAGTAGTAGC CCATTTGATG CCATTTGACA GATGAGGAAA CTGGCATGGG AAGGCCCCTG ATGAGTCTAC AGCATAGGCA AAGACTGGAC CAGCCTTGCT AGTCTAATGC CTACAGAATC TCAATGCCCA GATTTGTGGT

TCATAGAGTT CCTGAAAATG CACCTAAAAA TGTTGGCAAG AATGGTCATC GTTGTATTTA GCTCCATGGA CTTGTTCAAT GACTGGAACT CTGAAACACA GAGAAGAGCT AAAAGCCTAA TACAACTTCA GGAAAAATAA AAGCCAATGA TCTGAACTGG ATAATTCACC AGTCAAAGGA AATCATTAAT GCTTTTACTT TAAAGCAGTT GTGCAAAAAT AAGCACTTGA TTTTTACATG CCAAGGACCT GCACTAATTT CTTTCCAATG CAGTAGTTAC CACTTCCCTC TACTTCCTTC ACGAATAAGT AAAAGGGCAT GTTTAGAGAT ACTCTTGTAA GTGTAAACTA AGTTCATTTG GGAGCCTCTA TTTGAAAATA CTGGTATAAA AAAAAATCTG TCTCCTGATA CTAACATTTG AAGGAATCTA CTTTTTTACA TATTGGCAGA GGGTCTGATT CTATCCTTAG TTCTTCCCAT TACTTTGATG AACCTTTTCA AGGTGATTTG ATCCCCACAC CCAAATATAT GATTGAGAGA AGGCTCAAGT

TCCCAGGAGC TCCAGACAGA AGGTACCTGT TGGCTTGATG AAGATGAGGA GGAAATGAAC ACTAGCTAGG CCTTAAAGGG AAATGTCTCT GATAGGCCTA ATACACAGTC CTCTGCTAAA GGCCTCCCTG CCTCTCTCTG CTCATCCACT CTACTCCCTG GCCCTGGGCA CGCAGCACAC AGAGATCAGC ATTTCTGACA GCTTCTGTAG ATCCTACCAT TTAAAGACTT TTGTCATCCA TGCAGATAGT CTCAGGAGCA GACACAGGTA GCTATTCTTT CACATGCTAG CTTAACATGC ATTTGCTTTA GCACCTATTG CCAGGCACTG TGTCAGGTGG AGGGTATACA AAGATGAACA AGACATGATT CTTCTCATAT ACAGATAGAT TTTGGAGGCA TTAGCTTAGT GATGATTCAG GAGTATCCAT TATTTGGGGA AGTAGGTGGT CATTAGTGAC CTTTTACAGG CATTTCAATG GGCTAACAGA GATGTTAGAT TGTAGTGGAA TAGAAGAATG GGTAAAAAGT AAATCAGTGA GTTCAGATTT

TAGGAGTTAA GATGGCAAGA GGTGAGAACA AAAAAAGGAA ATGATTGTCA TTAAAGGAGG AGGAAAGACC AGCCAAAGAT TTTACAGTGA GTTAAGCATA CAAATTTATT TCTAGGCCAC ATATTCTTAG CAAAACAACA TGTAAATGTT TATGTATGTC TTTCCTCATA TCTGCTCATC CATCAGCTCC ATCGTTAAGA TTTCAGTTTT CCAGGACAAA CTTACTCACT TTGACATATT GGACTAGGAT TTGACCAGAT TCCAGATGAT TCACAAATGG TTTTCTTCTT CCCAATTAAC TCAGTTCCTT CTGAGCAGAT GAAGGTACAT GCAGAGGTAA AGCTGAAGCT GGCCAGGGGA TGGCTACAGT TCATGATCCC CAAATCTGGT GCTGATAGAG GCTCACACTG AATCACTTCA ATGAAAAAGA AAAAAAAAAA AAAGACAAAA CAGTATTTCT GAGTAGAGAC CCTCCCTTGA GCAAAGGATT TTTAGCCAAA GCTGCCTGAC TACATTACTT GTGATATTGC TTCCAGGCTT

TATTTTCTTG AGAATGATGG TGGGTGGTGA ATGAGAGATG AAGGCAAGGA AGCATTGAAA GCTGTGGGGA GAGGAGTAGC TACTCCAGGC TGCTGCCCTA GCTAAGGTGA CCCTCCCCTT CTGCTGGAAG TACCATGCCA TATGGCCTCT GCATCAAGGG CTCTTATGGG ATATTCTCAG AGAATCTCTG CCGTTTCATC TGTTCTGATA TCTACCCAAG CATTTTGAAA AACATCCCAA TTCACTGAAG CAAGTCCAAC TTCCGTAAAT TCCAGTAGGT GGGTTGACAG TTTTATAATT TCAATAAGGG ATTTTGATAG CACTTCTAAG AATTAAACTA CTTAAACTAA TGCATCAGGA GCATACTTGT AGAAAAGTTA ACCAAAACTT CGTAAGTTCA GATGACATTG GTTTTCTCCC ATATGGAGAT AAGGTTGGCA GTTAAAAATG AAAAAAAAAA AAAAACCTAC CTTATTTCAA ACTTGAAAAG ATCAAGAGAT TGTGTTTTTG TTTTTCAGTT GTTATTCTCC TAAAAGTTTA

TGCATGAGGA AAAGTAAAAG TGATTTTAAG AATAAGCCAA ATAAAACAAC CAAGAAAGAC CTCCACTACC CTGGGAAGGA AACTGGTTGG TATTAAGTAG GACACCACAT AAAACAGGTG TTATTGAGAG GAGAAGAACC AAAATGTAAC TGAGGTTCAA CAAGACATTA TTTATGCAAT GGCAATGAGA AAAATAAAAA ACACAGTATA ACCATGCTGT ATTGCTATAA GTCATGTTAC ACACTGGGAG ATGGCTTCAG GGGTATTTGG TTTTTACTTT TTGTTTGGGA GGTTTTTCAA AAAAATTTAG TTAGAATAAG TCCTTTGAGA AACATCACAG TAGGTTAAAC AAAGTTAGGT TAAATTAGGC TCCTAAGTTT GACTTCTCAG CAAACTTCTA CTGAATGTTC TGACTGTAAG CCCAGGATTG CATGACAAAA CCTCTAGTCT GAAGTTACTC ACCTTGACAG GTTGGTTCTG GAGATGACCA GTTTCCAAAT GGTCCACAGG TGGTTTCTTC AATCCCAGTT AAGTTTGTTC CTTCAGAGCA

GCTGAAGGCA CACTGTGAGC TGAAGCTGAA GTTTCCCAAA GGGTGAGTAC AGTCCATGGT ACCCAGCTCT GGGGCCTCCA AAGGCTCACA CTGAATCACT TCAATAGGGA AAGAAACAGT ATGGGGAAGA GTTAAGAGGA ACTGACGCCT GGATTTGAAT CCTAGCCCTG CCACTTGATA ACCATGTGCC TTTAAACAAG GTTACTTGAA CCCTCCAACT TCAGTTTCTT CATCTATATA AGAGGAATAA TGAAATTGTG TTATCTTTAT CAAATTGATA TGGAAACTAA ATGTAATTCA ATTAGCATAA GTCAAGGACC TTAGAACAAA GCCTGACTCA TCAGAAATTC TAAGTAAACA TTAGCTAGTC TTCATATTAT TATCTTCAGC ATTATCTGTA GTGAGAATCC TTAAAGCCAA ATAGGTGTAA CTGGGAATGA CCAGCTTAGT CGGGAAATAA CTATCACATC AGAGCCCCTG AGTCTACTAG AGTATTGGGA GCAAGATGTT CAGAGAAAGA GTGGGTCTCC ATAATAAGCC TTCTTTGCAA

GGAGAGAATA TAAAAGTCTA GGAAGCATTT TGACCTCAAT TCTGTCTTCT ATTCTAGCTC AGTTCCAGAA TTTTAACTCT TTTGATTTTG ACAACCCTCT CCAGAAACTG TATCTATTTC CCTGTTCTGA TTGGTGGTAC AATAGGTAAA TTTAAGACTT GGAAATCAAA GTTTTCACAT TTTAGACCCT GCCATGCCAT TTAGTAAACA GTACAACTTT CATGTCTTAT TCCTCATCTG TCAAATTTAA GCCATTATTG CTACCTTGCT CTAGAGACTT CAAGGAAGAA TGGACTCAAG GAATCAGAAG AATTTTTGTA TTTGGAAACT ATATGAGATG AGATTAGGGA GAAACATGGG AACTAAGAGA AAATGTTATC TTTTTTCATT GATTTAAAGA GTATCTATTA TATATCAAGC ATTACTCTGG GGCTTGAAGA GCTTAGATTT CACCCTGTAG GACAAAATGG TAGGTAGAAA TTAATGGGTG GATTGTCATG TATGTGTGAT GTGTTTTAAT TGCTTTTAAT TGATCAGTCT CCCTGTAGTA

TGAATAATGT ATTTGAGGGG AGCTAATTTA AAATTGTGGA ACTCATCTAA TAAACTATTG CAAGAATCTA GAAGAAAGAT AATGACGGCA ATGGTAGTAG AGTTGACAAG TGGAAGACAA ATTAGAAAAA CACTAAGTTG TAAAAATTGG TAGAATGTTA CCCTGCATAA ATGTTGGGGG AGTTAAGAGA GTCTCATACC AGGGTGCCCA TGTAAATGGT GATTCCACAT ACTGAGATAA GAAATACGAA GAGAAAAGCT GACTGGGAAC AATTGGTTTT ATAGTCTTTT AAACATCCCA AAGGACATCC TTAGCATATT TGAGTTCAGA GCTGGAGATA GGCTTATCAG TCCAAAGATC ACATAGATTT GTGAGTCCGC AAAAGTCAGT AAGTTTGACC AAAGGATACA TGTAGATTAG AGTCAGAAGA GCAATATACA AAAGACAAAA GCTGAGAAAT TATAGTAGTT TATGGTCCTG GATAAGTGCT CATGAAGGAT CTCAGGAGAA ATGATCACAG GTAGAAAGAA TGAGAAAAGA

GTGATATGAG AGAAACCAAG ACAAAGAAAA GTAAAATGTT AAAAATGAGT GAAATAGGCA TACCAATAAT TAAAAATGAG TAAAATAGGC ATACCAATAA CATAAGGGTT AAAAAATAGA GTTCAAAAAT GGGGTGAGGG TAAAGTATTA GGAAGGAGTC ATGGCCCAGG GATCAAGTGA AATGAGTTAG ATCTATAGAT CTATTTCAGT TGGTTGACAT TTAAATGTAT TTTGGTTTTA ATTCTTTATT GTTTACAAAC ATTGCTTTTT TAAAAAATTA AATTGTCCAA TTCAATTCAG GCTCACAAGC AAGTGCCTCA TATATACAGG CATTTTGTGG ATCCCAAAGA TGCAATGATA AATAGGACAC TTACTGATCT CAAGAAGTTT TCAGTACCAG AGGAGACGGA CAAGTGAACA GATGACTTCA ACATAAGTGG GAGAAATGAG GAAGAAATAT GTGGAGCTAT CAGAACTAAG AAAGCTTCCT AGAAGAAACT GTCTTTGAAC AATGTCTTAA AGATGACATG TTTTTTGGCC

ATGTGCAAAA TGAGAGAGAA GGCCACCAGC AAAGTCAGTG TGCTACAGAG CACATGTGTT AAGTGTGGAG AACTGCAAGA AGGAAAGGAA CTACTAGAAG GAAAAAGCAA GATACTTTCT GGGTAACTCA GCCTCCTAAT GATAAATGGC ATAGTTTCTT CCAGACCTTA GAGTTCTAAT TAATCTAACA AGCTCATTAG ATCGTGAGCT TCTTGAGAGC GGGAATCTAC CATGCTAATT CCTTATGGTA ACCCTGACAG CTTTTATCCC AACACTGTGC TTCTTGTGGT ACTCAAAAAG ACTTGTTGAG AAGTGAGTCG AAACTTCATG CTGACTTATG AAATCTTTAC GGAAAGGTAA CAATATTGTG AAAGCAGAGC TTTCTGATCA AAACTTCCCA TTTCTCAGAG TGGCTAGTAT CATTTTGTTC CAACCAGCTT CATGATAAGC TATAATGATT CCTGTGACTT TACCTAAGAA GAAGCAAAGA AAGGAAAGAG ACTTACCAAA CTGACACTGG GGCCCATAGT ACCCCACATC

ACAGTTGCAG GTGTAATTAT TGATGATTTC TACACATTCT CCATGGCCAC TGCATGACCA GGGCTGGCAA GAAGCTTTAA GGAGGTCAGA AAAAAAATAT TTTAATGTGA TTACATTTTA GTACTCAAAG TCATTTCTTT AGACATAGAT AACCTTTTGT CTGAGATGAT TTAAATAATC AGGAAAGGTT TATTTGTAAA TTCATAGCAT AAAAATCATA TGCTAAAATT TTTACGTATA AAATACACTA AGCATATAGT CATAGGCATT TATTTGCTTT TGGAATGAAA TTACCAATAC TAATATTCTG TAACACTTAT AGGAAACTTA GTGGCATACC TTGAAACTCT TGAAATTACT TGTTTTTAAT GAGTGAGAAG GTTAAATGAT GACCTGACCT CAATCATTTC TGCATGCAAT TATTTCTTGG CAATCCCTTT CTTTATAGAA ATCAAAGATT AAAAAGTCCA AATTTGCTAA AACGGTAGAG TCCAATTTAT AAGAGACCAA ATTAACTATG GTTCATTATT AAAACATCAC TTGGAAAATG

CTGGCTGTTT TGGAATTGTA GAAGATTTTA CAGAAATATT CATACACCAA AGATAGTGCA ATTTTTATAT AAAATTATAT AAGGTTAGAC CAAGAAGGAA GCACGCAGCA CCACACTCTC TACTTCACAA TGTGAAAACT GAGGTGATGT GAGCCTAAGT TTCCAACTGG CCCCAGCTGT CAGCTTCTCC TCCCCTGCCT TATTATCAAA GGCACTGATT GTCTAGCTCT TCCTCTGTAC TTCCTACGTA GATCTATCAT TTTGATGTAA CTTGATTTAG GGGTATAGCT TTTGTGCACA GGGACAAATC TTACACACCA AAAATTCTTA GGAGTGACAC GATGCAAGAT TATATAGAGG GCTAGATGTA TTTTAGAATG AACCAGAAGC TGTTCTCATC CCCCCACCTT TCCATGGGGT AAATCTGAGT ATTCTCTTAA CCGTGGCCCT TCCTGAGTCT GAGGCAGCAT AGCCGTCTTG TCACTCCCTA CCTGTGTAAC AGAGGGCTGC CTTTAGTTTG TGGCAGGCGT CATCGTTCCA TTTGCCTGCA

TCTTTGTTTC TCTTGATATA GATCTCCACG CAGTCCTCCT TGTTCTTCTT GTTGTTGGGC TCACCATCTC CCCAGTTCTC TGCTTCTTCA GTAAGAGATT TGTTGGTTCC CACCCACGTC CATATTCCTC CTATCTTCCG GATTCCTATC CAGTAGTAAG AACGACTGAA AGGCAGAGTC TTCTCCAGAT ACTCAATTTC CGCCTTGTTT TGTATGGCAA CTAAATCTGT GTAATTGTCT CGGCAGAATC TTCTAGCCCT TTGCCAGTTC ATGGGTTTTT CAGAATAATG GTAAGTCCAG CAGTCGGTTC CATGATGTGC CAGGAAATCT GCAAGACATC AGTGTGACCT ATGCAGACTT ACATAATGTT ACAGCTAAAA AGAACCTAGC ACTACTCCAG GCTGAGCTAG ACACTTAGAG ATGAGGAAAC AGAGCCTAAG AGTGTATGTG ACCATCTCAG GATCACAGAA TAGTTGTTTG CAGATTTGAA GTAGAACCTA GACCTTCTGG CTTGAATATA AGATGCTTTT ATCTAAGGTT CTATTTGAAA CAAATTTAGT GGTTTTCTAG GTTTATTTTC TTATTAATTT TTTTCTCAAA ATTATTTCAG GTGAAATTTA ACCAACATAT TTTAGACATT CATATTTCTT TTTCTTTGTA GCTGTTAATG ATTTACAACT AATTACCGTG TAATATCATA TAACTATACA ATTTACGTAT ACTTTTTAAT CCTGGAATCA TTTCTTGAAG GCCAACACAT ATGTACCTAT GGGAGAAGCA TAATAAGGAC AGGAAGAACA GTGACATACT TTTAAGTAAC CTCTTTTACA TAAAAAACAT TTTATTTTAC CATAGGAAGA ACTGCTTCTG GAAAAGCCCA ATATACCACT CAACTCTTAT ATATCTAACT GTATAATTTT TAAAAAGAAC AATTTACAAA GCCAAATGGT ATAGGATTAT GAAATTCATT AGATCATGTT CTATACACAA

AGAGACTCAA CTGATGATGT TTAATAAACA TATGGACCCA TCAAATATGA GGGCTTTGAA GATATCTAAT TAAACACATA ATTACACAAT GACTTCATAA TAATATATGG CATTCTAAGC ATGGTATGAT CTACATGAAT CACTATTTAA TACAGTAAAG AAACAGATAT AATTGATGGT AAAGAGCATC ATAAAATAAA CATTTTGAAC AGAGTTTTGA ATGAGCATTC CACTAGAATG CAAGTTCTAA GAGGGAAAAA ACTGTTGTGT CCACTGGTGT ATCCTTAGTG CCTAGCATAA ATTTCACACA TTGTAGGGAC TCAGAAAATA CCTGTTGTAT GAAAAGAGCA CTAAGTTTCT ATGTGACACA GTGCAGACAT GGCATAAGGA ATGTGTGAAC GGGAGAGTTA GCATGTTTGC TTGGCTAGAG CTGAAAATCC AGGCTAGGGA GAAAGAAGAC ATTAGTTTAC TTAGGAAATG AAAAACCAAG TTCAAAGCTA TTGCTGGAGA GTCTTCAAGA ATCAGATATA AAATTTGTCA CAACAATGGG

AGAAGGACCA AAAAATGATA AACCCCCGTC CCTTAATAAG CTCGTATTGT AATTGTAGAA ATGACATTAA TGTACACTGA ACTATGAATA AAAAATAGAA AATGAGGTGC TAAATATTTG GTACAGATTG TAAGTACCTT AACAGAGATT TCTTAATTAA CATTATTCCT TTATAATTGA GGGATTTTGT GGGGTTATTG GGATTTGAAC TCTACAGCAT GGGCTATTAT AGGTTAAAAA TAGTGTTCAG GAGTTTCTGG GGAAGAACTA AAGGTAAGAA GAAAAGAGAT GTTTACAGAA GGGATAGAAT TAACAGCTCT GTGAAATAAT TTTCCCTTAG ACTATGTATA ACTAGTGGAT ATTTAAGAAA AATGAATATA AGTAAAATAG ACTTAGCGAT ATATAAATAT CATAACATAC CACAACAGAG CATTGTCCAC CCCCACAACT TGAAGATGTT CCATAAGTCC CTCTGGGTGC TCTGACATTT CCATGGAAAT ATCTGCAAAT GAAATACAAA ATTATATTTA GATGTATACT CTTAAACCAC

ACATTTATAG CCTTTGAGGT GGTGCTTACA ACTTTCTTAA TAATCAGAAT AAAACACATA TGTCTACTAA CCCTGTCTGA GGTAACAGGT TTCTCAGACA TAGATGAAAA ATTACTTCAA ATTTACATCA GAACTGATGC ACAGTTTTGT TTTGTTCTAT TTTATTTTTA CGCTTTAGTC TCAAGTTGCT AATCGGTACT GCCCTGAATT TTTTCTATGG TTTGGTAATT TTTATACCTG CTTTTCTGCT GAGCTATTAG ATAAAACTAT TTAATATTTA CTATGTATAT TTTTTAAAGT ATTGTTGCTG CTTAATTAAC TATTGATGCT TATATTTAAT GTTATAGCCT CACTCTTGAT CATAATGGGT CAATGCCTCA AATACCTAAA AAAAAAAAAA ATTAGATAGC CAGACACCAG GAAAGAAAAG TATTTCTTTT TTTAATAAAA AGAAATACCT TTTTGAGCAA CTGAAATGAC AAAGTCACAA ATTTCCTGCA CACCTTAAAA TATACTTAAT GTAAATGACG AGTTAATGGG TGCAGCACAC

CAACATGGCA CATGTATACA TGTGTGACAA ACCTGTATGT TGTGCACATG TACCCTAGAA CTTAAAGTAT AATTTTAAAA AAATTCTATC TTCCAAAGCA TATCACTTCT CAGGTAGACA CAGTGTTTAT TGCAAAAGAT CTGATTTCAA TAGTATTTCT TCAAGAGTCT CCCCAGAGAC AAAGTCAAGA AGAGGAAATC AGCATATCTG AGAAGAAAGA TTTCAGGATC ACTTTTTTTG AGGGTCTGAG AAAATGTTTA GTTTCTATAT TATTTAAAAC CAGAATTGAA ATGGGGTGAT TCCTATCCTT GCCACCTGCC TCTACAACCC CAAGAGTTTC TATCTGAGCA TCTAAACGTC TTTTAGGCTG AAAGGCTCAC CATGGCTTTG CTTGGTCCTT CTCTAGTTCT TCTGCAGCCC ATTGAGCCTC TTGACTTAGC ACAAGGGTCT CAGGTCCTTG CCCAAAGGGA GTGTGCTGTG CTGCAGGTAG ACTGCACTGA ATGTCAACAG AAAGCCTTGC TTTCTTTCAT TTCTCTAACC CAGTCTCACA

TCCTCCTCCT CCTCCCCTTT TCCCTCCCCT TCCTCCTGCA CTTCTCTTTC CTCTTTCCCC ACCCCTTTCC TAGACTGGCC TCTATTGCCT CCCACTGAGA CAAAAATGAA CTGCTGATCA GAAAGTAATG TGACTAGATT CTCTCTTCCT TCCCTCCTTT CTATCCTTCC TTCCATTCTC CTATGCATCT TTCCTTACCC TCCTCCTCCT TCACTCATTG TTGTTGCTGT TCTTCTTCCT CTTCTTTTTC CTCCTGCTCC TCTTCTTCTA CTTGTTCTTG TTCTTGTTTT TGTTTGGTTC TTGTTCTCCT CTTCCTCCTT CTCTCTCTCC TCCTCCTCCT TCTTTTCCAC CACCCTCCCC TATCTTTTTC ATAAATGCTA AACTAACTCT TGGCTACCTG TGGTAAATGG CCCTTGGAAA TTGCAAATAC TACAAATCAA AACTGCATTT CAGACATATT TATGATGTTT GCAAAACTTC AGTAGAGCTA AGCAGTGGAC TTGACTCGTT TCGGTTCCTT CACCTCCGTC TTTCCTTGCT CACCACCTAG

TGGACGTCCT TGTTAGTGGC ACTTCCTGAA GTTAACCCCT GAAGAGAGCC CATGCTCTCT AGCTTTTCAC CGTGTAGGTT TGGGAGCCTA CAAGTACCTT TAATATTCTT GGACTATAAA ATGAGATGGT TTTATAAGAC TGCATGTGAA ATTAGGACCC ATATGATGAA GGACAATAAA AAGGAAGACC CACTGATGTG AGTCAATGAG TCAAATGCAA ATCAGATTTG CATTTTTAGG AAAATAATAA TAACAACAAC AAAAACTCTG AAGCTCAGCG CCCCATATTT ATTATATTGT TTAATCTTTA TAACAGCTCT CTGCTATAGA TATGATTATT ATCCCCATTC TAAAGAGTCT CAAAGAGGTT AAGAAACAAA TTCAAAAACT AGCGAAAGAC AAGAAATAAC TAAGATCAGA GCAGAACCAT AGGAGGTAGA GACACGAAAA AGCCTTCAAA AAATCAATAA ATCCAGGAGC TGCATTTTGA AAAGATTAAC AAAATAGATG GACCACTAGC TAGACTAATA AGAAAGAAGA ATCAATAGAC

ACAATAAAAA ATGGTAAAGG GGATATTACC ACTGATCCCG TAGAAATACA AACTACCATC AGAGATTACT ATAAACATCT TTACACAAAT AAACTAGAAA ATCTAGAAGA AATGGATAAA TTCCTGGACA CATACACCCT CCCAAGACTA AACCAGGAAG AAGTCAAATC CCTGAATAGA CTAATAACAA GTTCTGAAAT TAAGGCAGCA ATTAATAGCC TACCAACTAA AAAAAGCCCA GGACCAGATG GATTCACAGC CAAATTCTAC CAGAGGTACA AAGAGGTGCT GGTACCATTC CTTCTGAAAC TATTCCAGAG AATAGAAAAA GAGGAACTCC TCCCTCACTC ATTTTATGAG GCCAGCATCA TCCTGATACT AAAACCTGGC AGAGACACAA CAAAAAAAGA AAATTTCAGG CCAATATCCC TGATGAACAT CATTGCGAAA ATACTCAATA AAATACGGCA AACTGAATCC AGCAGCACAT CAAAAAGCTT ATCAACCACA ATCAAGTTGG CTTCATCCCT GGAATGCAAG GCTGGTTCAA

CATACACAAA TCAATAAACA GAATCCATTA CGTAAACAGA ACCAATCACA AAAACCACGT GATTATCTCA ATAGATGCAG AAAAGGCCTT GGATAAAATT CAACACCCCT TCATGCTAAA AACTCTCAAT AAACTAGGTA TTGATGGAAC GTATCTCAAA ATAATAAGAG CTATTTATGA CAAACCCACA GCCAATAGCA TACTGAATGG GCAAAAACTG AAAGCGTTCC CTTTAAAAAC TGGCACAAGA CAAGTATGCC TCTCTCACCA CTCCTGTTCA ACATAGTATT GGAAGTTCTG GCCAGGGCAA TCAGGCAAGA GAAAGAAATA AAGTGTATTC AAATAGAAGA GAGGAAGTCA AATTGTGTCT GTTTGCAGAT GACATGATTG TATATTTAGA AAATCCCATT GTCTCAGCCC AAAATCTCCT TAAACTGATC AGCAACTTCA GCAAAGTCTC AGGTTACAAA ATCAATGTGA AAAAATCACA AGAATTCCTA TACAGCAATA ATAGACAAAC AGAGAGCCAA ATCATGAGTG AACTCCCATT

CACGATTGCT ACAAAGAGAA TAAAATACCT AGGAATCCAA CTTACAAGGA ATGTGAAGGA CCTATTCAAG GAGAACTACA AACCACTGCT CAAGGAAATA AGAGAGGACA CAAATGAATG GAAAAACATT CCATGCTCAT GGGTAGGAAG AATCAATATC ATGAAAATGA CCATACTGCC CAAGGTAATT TATAGATTCA GTGCTATCCC CATCAAGCTA CTACTGACTT TTTTCACAGA ATTAGAAAAA AACTACTTTA AATTTCATAT GGAACCAAAA AAGAGCTTGT ATAGCCAAGA CAATCCTAAG CAAAAAGAAC AAAGCTGGAG GCATCATGCT ACCTGACTTC AAACTATACT ACAAGGCTAT AGTAACCAAA ACAGCATGGT GCTGGTACAA AAACAGATAT ATGGACCAAC GGAACAGAAC AGAGGCATCA GAAATAACAC CACACATCTA CAA^'CCATCTG ATCTTTGACA AAGCTGACAA AAAGAAGCAA TTGGGAAAGG ATTCCCCATT TAATAAATGA TGTTGGGAAA

ACTGGCTAGC CATATGCAGA AAACTGAAAC TGGATCCCTT CCTTACACCT TATATAAAAA TTAACTCAAG ATGGATTAAA GACTTAAATG GAAGACCTAA AACCATAAAA ATTCTAGGAG AAAACCTAGG CAATACCATT CAGGACGTAG GTATGGGCAA AGACTTCATG ACTAAAACAC CAAAAGCAAC AGCAACAAAA GCCAAAATTG ACAAATGGGA TCTAATTAAA CTAAAGAGCT TCTGCACAGT AGAAAAAAAA AAACTATCAT CAAAGTGAAC AGGAAACCTA CAGAATGGGA GAAAATTTTT GCAATCTATT CACCTGACAA AGGGCTAATA TCCAAAATCT ACAAGAAACT TAAACAAATT TACAAGAAAA AACAAACAAC ACCATCAAAA AGTGAGTGAA GGATATGAAC AGATGCTTCT CAAAAGAAGA AGTTTATGC A GTCAACAAAC ATATGAAAAA AAGCTCATCA TC ACTGGTC A TTAGAGAAAT GCAAATCAAA ACCACAATGA GATGCCATCT CATGCC AGTT

AGAATGGCGA TTATTAAAAA GTCAGGAAAC AACAGATGCT GGAGAGGATG TGGAGAAATA AGAATGCTTT TTACAGTGTT GGTGGAAGTG TAAATTAGTT CAATCATTGT GGAAGACAAT GTGGCGATTT CTCAAGGATC TATAACTAGA AAAACCATTT GACCCAGCAA TCCCATTACT GGGTATATAC CCAAAGGATT ATAAATCATT CTACGATAAA GACACATGCA CACTTATGTT TATTGAGGCA CTATTCACAA CAGCAAAGAG TTGGAACCAA CCCAAATGCC CACCAATGAT AAACTGGATA AAGATGATGT GGCACATATA CATCATGGAA TACTATACAG CCATAAAAAA GGATGAGTTC ATGTCCTTTG CAGGGACATG GATGAAGCTG GAAACCGTCA TTCTCAGCAA ACTAACACTG GAACAGAAAA CCAAACATTA CCCATTCTCA CTCATAAGTG GGAGTTGAAC AATGAGAACA CATGGACACA GGGAGGGGAA CATCACACAC TGGGGCATGT CAGGGGATGT

GGGGCTAGGG GAGGAACAGC ATTAGGAGAA ATACCTAATG TAGATGACAG GTTGATGAAT GCAGCAAACC ACCATGGCAC ATGTATACCT ATGTAACAAA CCTGCACGTT CTGCTCATGT ATCCCAGAAA TTAAAGTATA ATTTAAAAAA AGTTTAAAAA AAGAAAGTTG CCTTAGTCAC ATAACTAGTA AGAGACATGG TTGGGAATTT GAACAGAGGC CAATCAGTTC CAAATCCATG CTCTTGATCA TTAAGCTGAA CTTATGGCAG GAACTTGGAA GACATGGTAA AATGGGGAAA AACGTGGAGC CAGGGAGACT TGTGAAAGTG CCAGTGCTCC CACTATACCC TGAAAGAAGT ATCTAGACTT ACTTTTTTCT AAGTCCTCTC CTCTAATTCT CTCAATCTCT CTCTCTCTTT CTCTAAGAGA TGGGAATGCT GCTCTGTCAC TCAGGCTAGA GTGCAGTGGT GCGATCATAG CTCATTGCAC TCAAGGAATC CTAGGGTCTA GTGCCCCTTC TCCCTCAGCC TCCCATGTAG CTAAGACTAC

AGGCACATGC CCCAACCCTC GACTAATTTT TTTATTTTTT ATTTTTGTAG AGACAGGATC TCACTATGTT GCTCAGGCTG TAATTCTGTC TTGAAGCTTG TCCAATCAGG CTTTCAGCCA CACCAATTCC CTGAGACTGC TCTCACCAAG GTCCTACACT TCACTAACAC AAACAGCCTA TTCTCCATCC TCATCTTACT TCACCAGGGA GCTCCTGGTT TTCCTCCTAC TTCACTGGCT ATTTCTTCTG TATCATGTGT TGATTCTCCC TCATCTCCCC AACCTCCAAA CCCTTGGAGT ACTCCAGAGA TCACCGCTTT GCTCTTCTGT GTCTAACCTC ACTAACTTGG TGGTCCAATT CACACTCTTG ACTTTGAATA CCATTTAAAT GCGAACGAAT TCTAAATTCT GTACAACCAG AACCATTCTC CTGTAGCCAA ATGCCTACTC AACATCTCCA TCCCCAAACA AATTTAGTTG TTCAATAAGC CTCTCATATT TTACATATCC CAAACTGAAC TTCTGAATTT CTCCTCCAAT CTGTAGGGCT

CTTCCCACAG CCTTTCCATC TCAGTGGATT ATAACTCCAT CCTTCCAGTT ACTCAGACCA AAACTTTTGG AGTTAACTGA GACACCTCTC TTTTTTTTCA CAAGTCATAT CCAATGTGTC AACAAATTTT GGTAGTGGAA ATATTGCGGG ATTTTTTAAG AAATCAGAGA GACCGATGGG GTTCAGGAGG ATATTTATTA TTTAGGTGCA CTGGCCAAGT CAGATTAACA TCCAAAGGAC TGAGCCCTGA ACAAAGAGTT AAGTTACCTT TTAAGCATTT TGTGGGGTGG GAGAGAGGGG TATCTGTGCA GGGGGAAGCA TACTACAGAA GTGAGAAATA AAGACAGTTA TTCAATTAAT TGAGACATGC ATTACATCAT TTCTTACTTT TCAAGAAGAA ACATGTTTTG CGACTTGAGT TTATCTGTCT AGTGACCTTG CAGCTGCACA GCTAGAGAAA CAGGGTCTTC ACAATGCCTG GGAAAGGAGG AGAGGTAAGT CTCACTAGCC ACAGAAAAAC AGGCAGTTAA TTTTTAAAGG GCTCCAGCTC

TTTCTCTTTC TCAGGGGGAG TTGGGTTTTG TTACATACAA CTGAGTTTCC GCTTACACAT TATTTAATTT CTTTTAATTC CTGTTCCAAA AGAAGCCAGA TACAAAAGGT TACATGTTGT CTGATTCCAT TTATATGAAA CATATAGAAG AGGTAAATCC ATAGAGACAG AAAGTAGATT AGAGGTTCCC AGGGGCTGAG GAAGAAATGG GGACTAACTG CTTATAGGGT ACAGAGTTTT CTTCTGATAA AAATATTTTG GAACTAGATA GACATTTTGT TAGGCCATTC TTGCATTGTT ATAAAGAATT ACCTGAGACT TGGTAATTTA TAAAGAAAAG ATGTTTAATT GGCTTACACT TCTGCAAGCT TTACAGGAAG CATGGTGCCG ATATCTGCTC AGCTTCTGGT AAGGCCTCAG GAAGCTTACA ATCATGGCAG AAGGTGAAAG GGGAGCAGGC ATATCACATA GCAAAAGCAG GAGCAAGAGA GGGATGTGGG GAGGTGACAG TCACTTTTAA ACAGCCAGAT CTTGTGAGAA

CTCATTCACT ATCATGAAGA CAGTACCAAG AGGATGGTAC TAAATCATTC ATGAGAAACC CCACCCTCAT GATCAAATCA CCTCCCACCA GGCCCCACCT CCAACACTGG GGATTACAAT TTGACATGAG ATTTGAGTGA GAACACGGAT CCAAACCATA TCAGAGATGG TGGTTATACA ATGCGATAAA CGTCACTGGA TTGTACACTT TAAGATGGTT GTTTTATGTT GTGTGAACTT CACCTCAATA AAAAAAAATA TTTAATGTAC ATTCAGCCAA AAGAAGATTT GGAATAGGAA AGGTCATGGA GATATATTAA CAGCCATTTG ATGGGTGGTA AGGAAAAGAG TGGTTATTAG ACTGTTTTGT GGCCCTCAAA AGGTAGAACT AGATCGAGTT GGTGAGCATT ATAAAACCAT CACAAAACCC TGGAGAGAGG ACCCAGTGCT GAAGAACCGT TTGCCTGCCA TGAGACATGA GGGAAGTACC AGTGAATGCC ATTGAAAGCA GCATCCCTGG GTCCAAGGGA TGGTCAAAGG ACCACTACCC

AACCCTTCCC TAGCCTACGC CTCCATTACA GATGACCGCA AGATTTATTT GCTCATTGCT GCCAACCAAG GCTGCACTCA CTGCAGTTGC TATCAGTTTA TCATGGGTAA AAGGAATGTG CAGTAGAGAA CTAACTAACT GCCCACCTAC CTCCACAATC CTATCAGGAC AAATCACCAT GGCTCACATT TCCTTACATT TGGCATGTAA GCCCCTCTTA CTGTCTGTCA TCTATCTCCT ACACAGTTCA CCTAAACTGT TCTCTCCTGA CCCAACCTTG ATTTTCATCC CAAATGCTTC CTTGCCATCT CTGGGATTCC TGTCTTCACC ATCACCAAAC TCCCCTCAAT CTTCCAGTTT CCTGTTCAAA CTTTTCTCCT ACCTCCTTGC TTTGTCATTA GCCCGACTGC CTCCCTAGGA CATCACTTCC CCTGCAGATC TCTCAAGATG ACAATATTTA TTCTCCACAC AGCACATACT TCAGGGTTGG AAGGCAGGGG CAATCTTCTC CTTTATAATG AGTGCCTCTT ATATATGTTT ATTCATCTGC

CCTCTTGTAA AACACACACA CACACACACA CAAAGAAGAA ATAAAATAAC TCTGCTTCTT TGAAGCTTGT GACACTGAGA TAAACCATCT CACTGTCCTC ATTGTAGTGA CCTCTCAACT CCTCATGCAA GATTGGCTTT GGCACCTAGT TCCTGATCTT CCTTTCCCTG TAAGCACTTC TCATAGTCTT ACGGGACTTC ACCATCCATG GCACAACCAA TACCACAGCC CAGATCCTCA GCTCTCCAAT GACATTTTCC TCCACTAGAC TTGAGCTACC TCCTTCCCTA GGCACAGCCT CAACCTCGAC AACACCTAAG ACTGTACCGT CTCTAAAGTC ACATGTTCAA ACACTTCACT CTTTAACCAC TGTCTCCTAT TCTTGCAAGT GTATTGCTCA AGTATCTCAT TGCAATGCTT TTTACTTCTA CCTCATTGAA CCTCCAGGCC ATTAAACATT TCCTTATTTC TAACCATCAG GTTTCTCCTT ACTTGTTTGT TTGTTTATTT GTTTCTTTTT χχχχχχχχ_Tχ TXXGAGACAG GGTCTCACTC

TGTTGCCCAG GCTGGAGTGC AGTGGTATGA TCTCGGCTCA CTGCAGCCTC CATCTCCCTG GTTCAAGTGA TTCTCATGTC TCAGCCTCCC GAGTAGCTGG GACTACAGGT GCATGCCACT ACGCCTGGCT AAGATTTTGT ATTTTTATTA GAGAAGGGGT TTTGCCATGT TGGCCAAGCT GGTCTCGAAC TCCTAACCTC AGGTGATCCA CCTGCCTCAG CCTCCCAAAG TGCTGAGATT ATAGGCATGA GCCACTATGC CCCACCTGGT TTCTCCTTAT TTATTTCAAG TCTATGCTGC ACTATTAAAA CTGCCTTGAC AAAAATTATA ATAGTGAGAA AATTATGACA GTGAAAGAGA TCTGAAATAA TCAACCCCCA TCTTGCCTTT ACCTTCCAGA CTGCCCTTAA TAATTCCTGA GCTTGGGCCA AGCTATCTTT GGCAGAAATT TAGTTTATAG TTTAAATGAT AATAGCCCTT CTCCAAAACT AAACTGCCTT TGTAAAACTA ATAAAAGACC ACCAATGAAA GGTTAGGAGG ATGAGAGGAG CCTGAATTCT GCTAAGGTGT AGATGTAAAC AATTACCAAC TGTTATTCCG GAGGTCACAA GATTTGCAAC ATCGCCAATT ACTCCTGCAG ATAACAGCAC TATCATAGAA TCTGATTGGC CTTTTGAGAT GTCTTTTCAG ATTCTTACAT TTCAACTGGT GGCTCTACCT GGACCCATCA ACAAGTCCTG TGGCTCCACC CAGAAGCAGA CTTAACATGC ACAAGGACCA TTTTCCACAC CGCTATGATT GCATCCCAAC CAATCAGCAG CAACCATTCC TCTGCCTGCC AAATTATCCT TGAAAAATCT TAGCCTTAGA ATTTTGGGGG AGGCTGATTT CAGTAATAAC AAAACCCCGG TCTCCCATTT GGCTGGCTCT GCATGAATTA AATTCTTTCT CTATTGCAGT TCCCATCTTG ATAAATCACC TTTATCTGGG

CAGCAAACAA AAGGAACCCA TTGGACAGTT ACACTGTTGG CAGATATATC TTGCTTCCAA AATTGGATTT TTGTTTAATG AATTTATTCT GTTTTCTTGA TATTTACAAC TGTGAATGTT GTGTCTGAAT TCTCTTTATT TCTTGTTGAA AAGAACTATA TTGCTACAGC CAGTACATAC AGATGGATAG CTAATTACTC AACACGGGGG GATGTGACCA TCACCGCACT GTGCAAATGA ATGTTACCCA TTGTCCACTT TTCCCAAACT ACATAGTGTT ATATGGTATA TGACCCAATC AACGGTGGCA AAGCTCCAGA AATACCACAT AGACATCAGG GACACTTTAA ACTAATCAGC CTATAGTCCT TTTTCAGTAA TTTCCAAACC TGGTTGTGCA TCCAAATCAC TTGGTAACAT TAAAAAAACA AAAAAATATA CACGCAACAT TCGCTCCCAA TCCTACTGAA TCAGAATATT TTGGGTTGGT TCAGGAACAT TCAGGAGTTT TTCAGGGTCC AAGGTTTATA TAATTTGAGG TCTCTCTTTG

AGAAAAGGAA CGTAAAAGCG TCTTGCTTTT ATAGATCTTA CAAAGATGTA TTACCATGTA AACACATTCC TAGGACCCAG GCCCTTGTAA TTTAAAGGTT TATCTAAGTA ATGGGCCCTG AAGCTTAATT TTCATTATCT TCAGGGCAAA TTACCTGTGG GTTAGGGTTT AGGAATATAT CTCTCTGTGT ATGTGTGTGC ACATTAGCAT GTACGCTTGT GTGGATTTTT _ττττχ_TTχχχ TTTTTTTTTC TGAGACAGAG TCTCGCTCTG TCGCCAGGCT GGAGTGCAGT GGCGTGATCT CTGCTCACTG CAAACTCCGC CTCCCAGGCT CAAGCGATTC TTCTGCCTCA GCCTCTTGAG TAGCTGGGAC TATAGGCACG CACCACTATG CCCAGCTAAT TTTTGTATTT TTAGTAGAGT TGGGGTTTCG CCATGTTGGC CAGGATGGTC TTGATCTCTT GACCTCGTGA TCCACCCGCC TCCACCTCCC AAAGTGCTGG GATTACAGGC GTGAGTCACC ATGCCCAGCA CTTGTGTGGA TGTTTTAAGC

TCCCAGGTGA GTGAATACAA AACTAGATCT TTCCCTTCTG TAGCATCTGT ACTGTTTACT CTATGCATCT CAATATTTTT TCTTTTAGTA TCTTTCCTTT TTCTCTCTTA TTACTTCCTC TTGTGCTATT TTTACACCTC CTTTTTTAAA AAATTTTTTC CCTTTTATTT CTATTGACCT TTAGCCCTCA CAATGATTCC TACAAGCCCC ATTTCTGTAA ATGGGGATTG AAATAATTGC TGGACTTTTG AGAGATAGAT ATATTAAATT GCAAACTGGC AGTAGTGGGG GCAGTTGATA CATAACTAGG TTTTAAAGTC TAGCCTTCTG AGACCACTCA TTCCATTTGT GAAAAGTGAT TCTACTTCTT ATTATGAGCC AAAATATGCA TTCATTCACC CATGCATTGA TTTATTCATT CAATAAATAT TTGTTGGATG TCCACTCTGT ATCAGGAATG TGCTAGGTTC TGGGAATACA GCAATGAACA AGGTAATTTT TCCCTACCCC TAAGGAACTT AGAGTTTAGT GGGGAAGACA GACATTAAAC

AAACAATTGT GCAAGTAATA ATCTATAATT ATTTATTACA ATTAAAGGAA GGAAGAGACA TATGGATTAT GAGGGCATTA AAGAGGAGAC CTAGTGTAAG TAGCCAGTTC TCGTGAAGGG ACATGTATTA GTTGGAGTTC TCCAGAGAAA CAGAACCAAT GGTGTGTGTG TGTGTGTGTG CGTGTGTGCG TGTGTGTGTT GGGGTGTGGG GGTGTGGTAT TTTTTATAGA AATTGTCTCA CACAATTATG GAAGCTGAGA AGTCCCATGG CCTGCTGTCT ACGAGCTGAG AACCAGGAAA GCCAGTGGAA TACTTCAAAG TCCAAAGGCC CTGGAACCAA GAGTGCCAGT GTTGGAAGGC AGGAGAAGAT GGGTGTCCCA GCTTAAAAAG ACAGTGAATT CACTCTTTTT GCTCTACATA GGGCCTCAAT GGGTTGGATC ATGGCCACCC ACATTGGTGA AGGCAATCCT CTTAGTCTAC CAATTAAATA CTAATCTCTT TGGAAATACT CTCACAGACA CACTGAGAAA TAATGTTTTA TCAGGGTGAT

AGAAATCTTC TGGAGTTAAA CAATGGTGAT AGCTGTACAA TCACATACAT TTTTAAAGGG TGCGTTTTAT GGAAAGTGAG TTTTATCTAA ATAAAATTTC TAAGAAAGAG ACTTAACACA GAGATAAACA TAAGCACATT TATTGTCAAC CTTTATAGTG TTATGTCAAA TAGGTCTGAC ATAAGCTTAA ATAAATATAT ACTTTAAAAA TTATAAAATA TTTTAAGTTA TAATTTAAAA TTCTCAATAA AACTCAAACA CAAACCACAC TGGTATTTCA CACAGCTAAT TTCTAATGCA GTTTACATAA ATATTTACAA CACTTAAACA ATTTCAAAGA AAATAACACT GTATTCCATA CATAGCCTGA TCACAGTAGT TGTTCTCTCT TATTTCCCAG AGTTTTTCTG CCCCTTTAAA AGAACCTCTG CTGTTCTGAT CCTTATCACA TCTCTGTTTT GACTGTTGGC TTTGTTGTTG CCAGTGTTCA GCCAGAACTT CTCTGAAACT TTTTTTTCAA CACATGCTAA GTTAATGGAA GTGTAGGAGA

GTTTTGATTC TCACACTCCT CAAGGCTAGA GCAGCTTTGG CAATTACTGA CTGAGAATTT TTCATTGCCA GTGATCAACT GAAAACTGGA GATTCCTTTG GAATTGTTAA ATCTGCTTAT AAATAAACAT AAATGCTTGC TCACACAGGC ATTCCTCTCT TCCAGAGCAC CCTAACATAC AGAAGAAAAC AAATAGGGAA TAACTATTAG ACATCTTCAT TCGTTAAAAA TCTACCAGAT GACTCTTTTA CATGGTGAGT TTCTATTGTG AATTTAAAAT CTTCCATAAT ATACAAGAAT TATGTTTACA TATCATATCT GACAAACATC TTTGTAGGAA TGCAAAGCAC ATCCATCTTT CTGTATTCTT TTCCAACAAA GACATTCATA AAATTATACC TTTGTGTGTT TGCATTTATG CTTTTATTAG TTCAAAACGT TTGGCCTCAT GGAAGTTTTT CATCGTGGAA ACCACATATT TCTGAAAAAA TATCTGACAA TATACAAACC TTCCATTCAG TTTTTACTCT CCAATTCTAC CATGTTTTCA

AAAAACAACT GTAGTAAAAA CACTCAGAAC TTTATTCTGG TTAACATCAT GCCTTGCTAG GGGACAATAG TTTCCCTTTT TGAAATAAAT TTAAAACAGA TGTAACATAA TTTGTTAATA AACAATGAGG GGGTAATCTA GAATAAGTAA CTTTTACCAT ATCATAGTTG ACAGCATTTA CAAGTTTTTT AAGTCCCTAC CACACTTGTA TTGAATGAAG AAGTATGGAA GATTATAATA TATTCAATGC AAGTAAAAAT ATCACAATCC TTAAGAACTC TTTAAGAAGC ACTGAATCCC ATAGGGATGA AAGTGATTAA ATTGTGCATA GTAACCCTCG CACAGAGCAT TCAGTAGGAT TTGCACCATT AACAACCCTC CATGCATTTG CCTGTGGGCA TTCAACATCT GTCATTTTTT TAAGTTATAA TATTTTTAGT CATTTTTTTC CTCTAAACTC TGGATAATTA TTATTCATTC TTATGACAGC AACTGTGTAA TCAGCTGTCG AAACACTGTG AAGGGCAAAA GAAAGAAAGC CACAAAATAT

TGTGTTTCTG TGCCAAGATT TTACAGCGAG CAAGGGAGAG TTAGAAAAGG AATTCTGAGA TTTCAGAGTC TTGGTCTCTT CACCTTTGCT TGGAAGAAAA TATCCTTTCC CTTCATTAGC CAACACTTTC TTGATCCTGA GAGTAGGAAA GGGAACACTG AGTCTTTTCA GTTGAAGGCC GTCCTTGCCT GCTGGACTTT GATCTATTGA AGTGGTGATG GGTGTTGCGG TTTCAGCCAT AAAGGCATCT GGCATAGTAG GCAAGAAGGG CCAGAGACCC GAGGAGAGTT ATCTGTCTCT GTTAACTTCA GTGTATCCCT CTAGTTCCCC AGATGCACCT GTTTCTGTAA ATATAAACAT GCATGTCATC AGAACACTTA ATATTCTGCA TACTGATCAT GACAACAAAA TGTACCTTCT AACACAGACA CTCTCACTAG GATAGACCAT GTAGGAACAT CGAATTCTAT TCAGTTAGGA CAGTGATGAT GTCTACATAT TATACCTCTG TCAAAACCTA CAGAATATAC AACACAGCAC AGAGTGAATT

CTAATGTAGC CTGTGGACAT TAATGAATAA TAATGTATCA ATATTGGCCC ATCAGTTGTA ACACTAATAT AAGATGTTAA TAACAGGGGG AATTGAAGGG GTGGTGGGGA GATATGTTGG AACTCTTTGT GCTTTCTGCT CAATTTTTCT GTAAACTTAA AACCGCACAC ACAAAAAAAG TTATTTTAAT TTTTTAAAAA GTATTCAGAG GGACTTGACC TTTCCAAATT CTCTCAAAGC AGGTCGGAGT AGTTAAGAAC ACAAATTTTA GAACCAGACT GCCAGAGTTT GAATCCTGGC TACACCACTT ACTAGCTTTG AGATTTCAGA CAATTTACTT AACTTCTCTG TCTCATTTTC TTCATCTGTG TGATAAGAAA TAAAGTAACA GGCCAGGCCC AGTGGCTCAC GCCTGTAATC CCAGCACTTT GAGAGGCCAA GGCGGGTGGA TCAGGAGTTC AAGATCAGCC TGGCCAACAT GACGAAAAAA TACAAAATCT CTACTAAAAA TACAAAAATT AGCTGGGTGT GGTGGCAGGC ACCTGTAATC

CCAGCTACTC AGGAGGCTGA GGCAGGAGAA TTGCTTGAAC GCAGGAGGTG GAGGTTGCAG TGAGCCAAGA TCATGCCACT GCACTCCAGT CTAGGCAACA GAATGAGACT CCATCTCAAA ATTAAAAAAA AAAAAAGTAA AAAGAAAAGA TAAGAAATAT AGTACCAGCC CCTATCTCAG AGTTCCTAGC TTAGAAAAAT TCCCAGAATA TAATAAGTGC AATGTAAGGG TCAGCTATCT TCATTATTAT TATCTATCAT AAATGAAATT ACACAATAAA GCTAGATCCG TTTCTTTCCT CTCCTTCTAC AAAAAATAAA GCAACTTTCC AGAACAATAC CCAGGTGATG ATTTCTCCCC TGCTCCCTCC CTAAGATATT GGCAAGTTTG GAGGGTTCAA GGAGAAACAG AGCATGTAGA GAAGATACCT CTCTCATAAC CATTTGTGAT TTACAAGTCT TACCTGATTC TTTTGAACTT AAAGGATGTA AGAAGGCTTT TGGTAGCTTC CATCTGATTC AAGGCTTTGG CAGCTGCTGT

GGAATACATG AGAACACTAG GTAAAGCACT GTCTTCCAAC ATGAAGAGAG AAAAATATGT GGAATGTTCA ATGGCATGCT TTGTATAAGA ATGCAACTTA CCTGGCAGGA ACAAATTTCT TTGCTGCAAA AGAAAAGACA AACAACCATT AATTCAGACT AAATGACTTT TAAGGATATA TTAAATCCAG ATACAATATG ACTTAATTCA TCAAGTGTTG CAAACTCGAT GCTTCAGGGC CTCTGTAATA ATCAGAGCAC AAGCATGGCT CTGTGGCATC TAGGGTAAAA TGCAAAGTGC ACAGCCATCC AAAGGGCATA GCAGCTTCCT AATGCCAGCA AATAGCTACG GGGTCATCTT GCCCAATTCA GCTCCCAATT TTTCATGAGA AGTCCAAAGT CTTAATTTAA ATGTGAGATT TCCTATTTTG TAAACGTCAG AACTTAACTC AAAAATGTTT TAAGTACTCT TAAACATGTA AGCCAAACAA ACCATGAGTG TAGTCAGATG TGCTTCCATA TTCCTTATGA GAGACTCTCA AATTTAAGCC

TGTACTCCAA ATAAATCTCC TTAGGAAGAA TTTTATCCAT TTTCCTTAGA GTGCTCATCA TGGCAGTTCC ATTGCACAAT TCCGGGAGGC ATCATATAAT TCAACATGAA TAGCACCCCC TGGAGTTGTA CAATATTAGG CACGACTAAC ATTTTTATTT CCTGAAACAC TTCCCACACT GAGTTGTACT ACTAACTCTT TTCTTAATAC TTCTGCTTAA TTATACTGCA TTTTATCCAG ATTCTAATTA TTGTTTAAAT CAGTAAGCAA GACCATGACT TATCAATGAG AAAGAAATGT ATTTTCAAAA ACATTTTTGA AGTACATTCA TAAACTTCCT CACCTTTCCG TAAGCATTTC CGAAGCCAGA GGAGAAATGG TGCTAATGTC AGGAGGGAGA GTCCAGCAGC AGAAAGTCCA GCTACCAAGG GAATGTTGGA CTCAGTGGGA GCTAAGGAAG TAAGAGACGA AGAAAGGTCA TGAGGAAGAA TTGATGTTAA AGTCTCTCCG TCCTGTCCCT TTGGCCTTTT TTCTGTACAT TCATTACTAG

GAGCAGAAGA GCTATCTAGT TTAATACAAG AAGCAGAGAT GTGGCATTAC AGGCCTTTGA GATCTGCTCC AAGCCACCTT TGAAGCTATT TCCACCATTG GGAGGCAGAA CTCTAACTTG CCAAGCTCGT TCACAATACC ACACCACACC TTGGTTAATA AACACTGCAC TTGCTTGCTC TCTTGCTCTC ACTCCCTCTT GTTTTCCATT TCCCCTTTCT CCTCTCCTCT CTCTGTCTCC TTTTTCCAGT TGTCAGAATT CTACCCTTTC CATCAACATG CAACTTCTGT TTTTTCTCTA TCCCCATACA ACTTAATATT CACAACTTGT CAACCTGGGC GAACTTTCTG GTTTGGATAT AATGAATAGT TGATTACTGT AACAAGATAG CTCCCCCTTT TTCTTTTTAA TCACCAGACA ACCACCATCA ATCAATGCAT CACCTTCACA GGTAGGTAGC AGGCCAGACC AGTGTCCTGT GGCTCCACAT GTCCGAGCTG CAGAGCCATT GAGCGTCCAT CCTTCAGGAC AGGCGAACTT GCACACAGTG

CCAAACACGG GCTCCCCACT GCAGCTCATG TTGATCTTTC CCGGAACTGC CAGGCTTGAA CATTTTACCA CTGCAAATGT TAGGTACACA GGCAGAGTTT CAGAAAAATC TACTGGAAAA CTTCCAAAAC TTGCTTAAAA GTCAACAATG AATGTAAAGT GTAAGCGCTA CTTAGTTTTC AGCATGTAGG AAATTAGGAC CAAACCCCTT TGGGGCAATC TAGGTTCAGA AACTTTATGA AGTATTTGAC CTGTACCCTA AAAAAGTCTG CACTCAATTC TACCTTGGCA GGAAGGAACC TCTTCTGTCC ATTGTCCCTG AGATGTGCAC TCAAGTTGAG TTGATCCATG TAATTCAAAT CCCTCCTCAC AGCTGAAGGC ACAAGAGGAC TTGTAGGTGA ATTCTCCAAT AGGGGAATGA GCACACCTCA CCAAACCCTT CGGGGGCTGG TGGACAGCAT CGCATCTCAC AGCTGGAACA CACGAGAGAG CACTTTAGAA GTTTGTTTGC ATCTCCAGCA ATACGTTTCC CAAGGTAACC AAGTTCCCAA

GCTCTTCAAT AGTTCTTTTT ATCTTAAAAT AAAATAAAAA CAAAGACTGT ACCTTCACAT GTGGGCTTCT CGTTGTCCCA CTCCCCTGTG GGGCCACATT GGAGCCTTTT GGATCCCTTC AACACAAAAC CCTGCTCACA GGAGAACTCA CAGCTGGACC CATAACGGAA ACTGCCAGAA GCACTAGGAA GACAATTCAT GTAGCCTCGC TCGGGGTTGG ACAAGGCTGT GCACTGGAAA GCTGAGACAT CAAAATGATG GTCAGAAAAT ATTGCAGTGG AACTAGAGAG TACTTGGCGT TTGTTGAGTG AACCCAGTTC ATTCAAGCAA CACTTGGAGA ACTGAAGATT CTTTATAATT CCCTGGACAA ATGGGAAGAT GGCTGTGTTT TCTTTGAATT TCAGCCCCCT CACTGATCAT GGCACTAATT AAAAGACTAA TTAATCAGAA CATTAGTTCC TGAGCACTGT TCTTCTAACA CACAAAATAA ATTATGGTCC AAGGAAAGAT TTCACGCAGT CTGAGGACAA CATATGGGTC ATGGATGTTT

ATAGATGGTG CCAAAAAGAA AGAAAAGAAA GCACCCCTAT AAAATTTGTC TGTTTTGCAG TTTGGTTTTT GTGTTATGTT TTGCTACTGG AAATCATTCT GTGCTGGCTT TGGCTAGGAC AAGGCCAGTG CCTGATAGTA AAAACTGCTT GTTTTCAATA TCCTTGCTCT CACTTTAAAG TGAATTAAAA TTTACTGCTT ATATATGCAT CAATACTATC TCTGTAGCTG ACACCATGCT TGAAACAGTC TCATCACTGC TAATTATGAG CCATTTCAGA AGACAGGTGT GATGAGAGTT TTACATTCAA ATCATGTTCT CATTATTCTG CTTTCCGAAT TTTCTAATAT GATTCCTTTA GATTAAGAAT TCTGTCTATT CCATGCTAAT GTCTACAAAG TTTTATCAGC ACATCACAGT TAAAAAAAAA CAGCAAAGAA TTCATTCTTA ACACATATGA TCCTTTCCCT GGCCAAACAT TAGTTCTTTT AAATGAATCT CAAAGATACG AGGGTTGCTC ATCAAATCTG ATTTCTATAG TTAAAGTGGG

TATTGGTTTT TTTTTTCACT GTCCAAGTTT GAAGATGGTT GTTCTTTAAG AAAGTATAAA TCGAAGGATC TCAAGCTTAC CTTCACAAAC TGGGATTTGC TGTGTCCACT GCCCTTGAGT GGTGCATTCA ACCTGGGCTG GTCCCTGCAA CATGAAGCCT TCCTCACAGG TGAAGTTGCA GGATGATTTG AAGGTGAACT CTCCAGCAGG GGAATGGCTG CACCTCACAG AGCCATTCTG AGGCTGGCGG ACGGCCCTGC ATGTCACAGC TGTAACAAAT ATACGCATTG ATATTAGCAC GGCCTAGAAT TAGCTTGCCC ATTTCCAGTA TGGGTTGAGA GAAAGAATGT TCACAGTAAG TCTCCATGTG GAACAACTCT ACCTTTACAC GTTGGCTTCT CGTTGTCCCA ATTCCCAGAT GAGGTACACT GAAGGCTCTG GGCTCCCATT AGTTCAAATC CTTCTTCACA GTCAAATGTA CAGGTTGTGT TCCATGGGAA GCTTCCAGGG TTTTGGAAAC ATTCCACGAA CCCATTGGCT GGATTTGTCA

CAGCATCACA CTCAACCACT GAGGATTTTA AAGAGCACCA TGAATTTTAC AGAAGAATGA TCTTTTCACT TCCTATTGAG CTGGGTGCCT AACAGAGTGA GGAAGCTGCC TTCAAAGGGT AGATCCCAAA GTCCTATGTC AATTCTTAGG GACATGCACA GCCAGAATAA AAGCTTTTAT TCTTTTTCAT GGATATTCTA TCTTTTCTGA TTTCCACTTT GCCTATGCTG AGTGGTCTCT AATCTATGTT ATCATTTACG TGAGGTAAAA ATTTAAAAAA AATAGATTCC AGATTAGGAG TTATGACTAG TACTGACATA CGTAGGCTAT TCATTTATTT TAGCCCATCA GAGCCTGAAG AACTGATTTT TCTTTTTTTG GCCTCTGGTT CAGAAAGATA AAATTAAGAG AGAAAAAGAG ATACTAAGAC TGCTTGACTA TCATGGTCTT AAGTTAGTCC CATGGCTTGG AAAAGTTAAA CAGGGAAACA AGATGAGAAA TCCATTGAGA TTTCTAGAGC TTTATTGTTT TATGGTCTCC CTTACAAATC

ACCAGAGCCT CAGAAACACC CATTTCAAGC ATAGAATAAA AAAACCTCTC TCAACCCAAG CAGGTACTGG GTTGGCAATA TACATTGGCT GAGAGAACAA ATTGTATTAA AAACAAAAAC AAAAAAAAAA CTTTCCCTGA AGTTTTGAAA ATGTAAGTTG AATCAAAAAA CAGAAGCAAT GAGGGATGAG TTACAGAACG TTCTGTGCAT TCTCAGAGGG ATTTACCATT GCAGGCTGGA ATAGGAGCAC TCCATTCTCC AGAGGACATA CACTGCATGG TCTCCATGCT GCTTGGCAGG TAACCCCTAT CACAGCTGAT AGAGCAGGAA GAATTGTAGC TGAAGTTTCC CAGTGGGTGA CTGCAAACCA GGCTTCCATG CTCAGOGGAT TCCAGGGCTG TACAGTTCAC AACTGAAAAA GAAACCCAAA TCAGTTCTGC TCATCTCTCA CCTTTAACAG ATAAGAACAC TGGAAACTAG AACTACAGTT TGGTTTTTTT TTTTTTTAGT TTAAAAATTT ATAAAATTTC TAATGGAATT TGTAAAATTG ACTGTAATTC TACCCCTTTT CTTTTATTCA AGAAAATGCT GATCCATAAC AACAACAAGA AAAAAGCAGT GATGACAACC ATAAAAAAGA AATATTGAGT GATATGGGGA GAGTAGTGTA ATTGTGTTTA CCTCAAAACT GTTCAAATTA TATGAACAAA CACAGCAAAC TTAGGTACCA CAACAAATTT CTTGTTACTT TTCTCACAAC TGCTAAAAAT ACTACAGTAA GCTTCCAACC AGGATGAGAA CCATTCACAA AGCTATATTT CAAATTTAAG TACTAGAATA CATTACAAAT TTTAAAACCC TAATGCTGCA CTGTCTACTA TAGTAGCCAC TATCTGTGTG GCTACTCAAA TTTAAACTTG AATTCGTTGA AATCAAATAA CATTTAAAAT TCAGTTCCTC AGTGTCACCA GCCACATTTC AAGTACTCAA

TAACCACATG TGGCTCATAG GTACACACTG GAAAACACAG CTATGGAACA TTTCCATTAT CACAAAAGCT CTACTGCACA ACGCTGTGCT AAGGAATCTT GGAGAGAAGC TCATCTAACT CTCTTAATGT ACAAATTTAG GAACTGAGAC CTCATTTCAT TCAAGTGACT TGCTCCATGC TACACGGCTA GTCATTACAG AGCCAGAGGC CAGAGCATGA ACCAAGATAC CCTGGACTCT GTAACTCACT CATTTCTACT GCAACGTCTT GTTACCACCT AGATGAGGTG AGTACATGTT CCTCGCAGGG ACACAGAATT ACAGTTTATT GAATGTGTCC TGTGTGCCAG GCACCATGTA ACCATGAGCC TATGAAGTTC ACACTATTAT TATCCTCATT TTACAATGAG AAAACTGACA TAGAGAGTTA AACTATCTTG TCAAGGTGCC AAAATAAATA ACTGGTGAAT CTAGGACTCA AACCCAGCAG GGTCTGACTT CATAGTCTCA GCTCACGATC ACCATATGAC ACCATCTGCA CCAGGGAAGG

GAAGGCATGC AGACCTGACT CTAATGCCAG CTAGGACGTG AGATGGTGCT ACCATCTCAA GTGAAGAAAG AGGCAAGAAC CAGACTTACT TTGCTCACAC TTGAGTCCAC TGAAGCCAGG GTCACACTTG CAAGTGTAAT TATTGATGGT CTCTACACAT TCACCGTGGC CACTGCAGGA TGTATTGGTA CAGGCAGCTA CGGAAAATAC AAAGCATGAT GAGGAGGACT ATTACTGTGC TTATACTGAG TGCCTTTGAT TTTAGAATCA ACAGTGTGCA ACAGAGACAT CAGCAGTCCT ACAGAGTGCC ATAGACTTTA ACTGAAGTGT TTTACAAAGT TCCAAATCTG AGTTTCAGGC CCACCTATCC TAAACCTTGA TGCTAATGTA TAGCTGTGGC TGGCACCTAC CGTAGAAAAT TTACTTCTTC ACAAACTCTG AAGACAGTTC CCCTACCACA AATAAACAAG TAATTAAAAT ATGTATTGTG TGTGTGGATT TTTATATGTA AAGAACTACA TATTTGCCTA CAGTATTTAT ATATATTTTA

TATATATACA TACACACATA TATGTGTGTA TATGTGTGTA TGTATATATA TAAAATGTAT ATAAATGCTG TAGGCTATAT ATATATACAC ACACACATAT ATGTGTGTGT GTATATATGT GTGTGTGTGT ATATATATAC ATATCCACAT ATTCTTGCCC ACATTCACAC AAAACAGCAA AAGAGAGAAA CTTTAGCAGT TAAACAGAAT CTTTTGGAAC ATAAAATGAC CACAATAGAG AGCAGTTTTT GCATGCTGTA AATTTGCCAA GATGCCCACA CACTGAAACT ACCTCCCACT GCTGCCGCAA ACTCCCTACC TGTGTAGCAT AGGGCAAGCT TCTTCTTGCT GCACCTCTCA TCATTCCACA TGCCCACATC TTTTTCTCTC TTGATGTAGA TCTCCACGCA GTCCTCATCT TTTTGCCTAT TGTTGGGTTC ACCTGGAGCC CAGTTCTTGG CTTCTTCTGT CAGAGGTTTC TGGGTTCCTA CCCAGACCCA CACATTGTTG ACTTTTCTGA TTCCAATCCA GTAATAACTT GGTGAATAGC

TCAATATGGA GTTTAGGTAC TCAATCTCTT CTTTGTTTTG AATTGCAACC AGGTGTGTGT ACCTTTGCTG ACAATAAGCA CTGGCCTCAT CATAAGTCAT AGCTTCCGTG GAGGTGTTGT AAGACCAGGC TCCACTCTCT TTAATGAGAA GCACTAGTGG GAGAAAAAGA AAAGAAATGG TAGAGTTTGG TACTGTTGTG GTTTAACTCT GACAACTGTG CTTTTTATTG TCTTATTTTT GGCAATGTTT GTGACATGGC CCAGACTTTT CTCATCTTTT CAAAAGTAAG AAGTACGTAT GAAGAAACAG CGACTTATTG TTTATCTCTT TTGTGACTGC CACCCACTAG GTACCTTATC CACACTCACT CACAACATTA TAGTATACCC ATTTTGTAGT AGAATAATAA TCAGAATAAC TAAGCTTTAT TGAGCACTTA GTATGCACCA AGAAGCACTG TATGAGGTAC TTTCCATGAA CCATGCTATT GAATCCTCAC AATGCATCTG GGAAATAGGT CATTATGATC CACACTTTAC ACTTAAGGAA

AGGGAGACAC CAAGAGGTAA AGTAAATGAC CCCAAGCCCA GGGAAGAACA CATTGCAGGT AGAGGTCAAG GATGCTGCCA GATATCCTGT GCAGGACAGC CCCAGACAAG CAAGGATATT TCAGTCTGAA ATATCTATAG TGCGAGAATG AGAAATCTTG GTCTAATGGC ACTGACTTAC CCAAAGTGAG AGCTGAGAGA AACTGTGAAG CAATCATGAC TTCAAGAGTT CTTTTCACCC AAAGGTTTAG GCTTGAAATA CTTTCCTGGG GAGATAAAAC ACAAAATGAA TTAAAGAAGG AAATCGTGGG TAGCTAGTTA CATTATTCTA CCATGATGTT TAAGGCAGCA TCCTAAGATT TTGGGCAAAG GACACTAGTG CAATAATCTT TATTTCAGAG TTTAATCAAA TAAATAAACA AATTTTAAGA CTTTCATTAT TTAGGTCAAA GAGAAAAGAC AGGTTTTAGC TACAATACAA TAAGAGCTTG TACAGATGTG GTTTTTATTA GAAGGCCTTT TGCATATCTG TGTTTCATGG

CCCGAGGCTG CCCTTATAAA GCGTTCTGCA CTTACCGTTT TGGGAAGCAG TTGTTCAAAC ACAGGATCTC TCAGGTGGGT ATCACTGCTG CCTCTGTCTC AGGTCAGTAT AGGAGTTTTG ATGTGAAGTC AGCCAAGAAC AGCTGAACAC TACTTCGGCT GAGGCCCTTT TATAGGAGGG ATTGCTTCCT GTGAATAATA GGAGGATATT GTCCACATCC AGTAAAGAGG AAATCCCCAA TGGCATCCAA AAACTTTCCC GGGAATATCC ACGATGCTTA AAATTACAAT GATGTCAGAA ACTCTGTCTC TTGAAGCTAC TTCACCTTTG TCCATGCCTT TATATCGTAT ATGCAATTTT ATTAATATGA CAAAAATGCA TGATTTTTAA TTATAATAAC ATAAAGTCTA TGTCTTTAAA AAGTTGTAAA ACTTTGCTTG TTAGTAGTGT CTCTCATGTA GTTGTGGTAG TAATTAGAAT TTCAGAAACA GAAGGAAACC AAGAATAGGT TTGTCATCCA TAGTCTACTA CCTTCAATTT CTCATTCATA

GCTGTGGATA ACCAATCACT ACTCATTTTT TCTTCCTTTT TCACCTGCCA ATTCAACATA TTTAACATGC ACTGTCTCAC AGAGGAATGA CTCACAAGGT AGATATTAAT CTTCAGATTT TGCACGGCAG TTATGCCTAA ATTAAAATAT TATCTAAAAA TAATATCTAA CACTCAAATG GTTAAAATAA TGCCTTATTT TAAAAAAAGA AAAATGGGAA ATAGATATTT ACATCTGGGA AAGTTTCATG GTTTGTTCAG TGAAAAAAAT AAAAAGGAGG CCAGGCACAG TGGCTCACGC CTGTAATCCC ACCACTTTGG GAGGCCGAGG CAGGCGGATC ACCTGAGGCC GGGAGTTCAA GACCAGCCTG ACCAACATGG AGAAACGCCA TCTCTACTAA AAATACAAAA TTAGCTGGGC ATGGTGGCGC ATGCCTGTAA TCCCAGCTAC TCGGGAGGCT GAGGCAGGAG AATCGCTTGA ACCCGGGAAG TGGAGGTTGC AGTGAGCCAA GATCACGCCA GTGCACTCCA GCCTGGGAAA

CGAGTGAAAC TCTGTCTTAA AAAAAAAAAA AAAAAAAGAA AAGAAAAGAA AAAAAATAAA ACGGAAAACT ATATATATAT ATTTAATTGG TCAAAATTTT GTTTAAAATT TTTGAAATGT TAATGTGCAA AGAATAAAAA TTCTTCCACA ATGTTAACAG TGACTAACTC TGGATGGCAG GATTTGGGAT AATTTTTATA TCCTTCATTA TTATTTTCAG GATTTTAAAG TTTTTTTCAA TTTCCCTTTT TTTCACCTTT ATAGTAACAA GAATACAGTT TAAAGAAACT TGTCTCTAGG CCAGGCATGA TGGCTCATGC CTGTAATCCC AGCACTTTGG GAGGCTGAGG TGGGTGGATC ACCTGAGGTC AGGAGTTCCA GACCAGCGTG GCCAATATGG TGAAACCCTG TCTCTACTAA AAATACAAAA ATTAGCCGGG GTGTAGTGGC GCATGCCTGT AATCCCAGCT ACTGGGGAGC CTGATGCAAG AGAATCGCTT GAACCCAGGA GGCAGAGGTT GCAGTGAGCT GAAATCACAC CATTGCACTC

CAGCCTGGGC GACAGAGCAA GACTCCATCT CAAAAAAAAA GAAAAAAAGA AAAAGAAAAG AAAAGAAATT TGTTTCCAAA TGCAACAGAA GGAGATGTAT GTGGTATCCT ATATTCCTGC TCTTCATTTT GACATTTCTT CTGGGTGATT GTATACATTC CCCATCTCTG CATCTTACCC TATCTAAATG ATGGTAACAG TAAATGGGGA TCATTTTAAT TTCCATATTC TGTAGGTTTT CAGAGCTCAA GTCAAGCTAA TATTCTATAT CTACAGCCTT TCAAAATAGG AGGTCTATCT AAAAATGTAC TGTCAGCAGA CCTGAACGAG TAGTGGTAAA AGCCTCGTTT TTCTCTTTAC TTGTTAGCAC TGGTCTTTCT GTGTTCATAA AGATGTCAAG ACCCAAAAAA AAAACAAGAA AAGAGAAGAA AAATTCCAAA AAAGACAACT GATTAGAAAA AAATAACTTA ATTAACGAAT TTAATTCAAC CCCTATCAAA AAGCATAGAA TTTATTCCCT CCACCTTACC ACTCTCTTAC

ATGATCCAGA TACTGACATT ATTCCAATTC TTTATCCCAC TTTACTTAGC TCAATGTGGT TGTTGCTTCA ATAAATTCAG AAGAGTAATC ACTCATATAG TGTTTATTTA

GATTTTAGGG CAGAATGTCA AGTTGGGTTA ATACATTATC TGTATGTATT TTATTTTTAA TAAAGTATGA ATACATAATC TGCTATTTTT AAAAAGCATG GTCAAATGTA

, TAGAGTAGCC AAATCTTAAA AAACAATTTA TCTTCGATAT CAATAAAGTA CCTAATAATT ATATTGCTAA TAGAAATTAG TCGTTAACAT CCCTAGATAA CTAACTTTAT

^' TATTGCGAAT TTTTCATAAC TAAGTTTATA GTTTATCTCT TCCCCTTTTT AAAATTAGTT CAAAGATATC TAAAAATAGC CCCAGTGGTG ATGAAGTTTC TATTTTACTT ACATATATAT GTCCTGGACC CCCAATTATA ATCTCTAACA TTTATTGAGT GCTTACTATG TGCCAGGCCA TATTCTGAGC ATTTTGTATG TTCACCTATT GATTATTCAA

TCCGTACAAC AGCCTATGAA ATAGGTACTC CTATTATCCC CATTTTACAG ATGAGGAAAT TGAGAATCTG GGGATTTTAT CTCATTCAAA AGCACAGAGC TAAGGGTTGA ^' AACCAGGCAG TTGATATCCA GAGCCCACTC CCTTACCTGC TACTCCAAAC CATGATTTCT TTTGTTGTTA TGCCCCGAGA TTCCTTGTTC TACCCAAGTT TCCTGTACTC TTCTTGCCCT CTTCTTCCTG AGACATCCTT GACCATCACA GCTCTCCACT GAGATAACTG TGTCCTGGGT TCTGAGACAT GGGGGCTGGA AGGGACCCCA GGGACAGTGA GCAGTAGGGA GAGGATGCAG TGAGAACAGA CCCTGGATCC CCGGTGCATA GGCAGGGAGA AAGTGGACAA AGGAAAAAAC AAGCAAGGCA GGTGGAGCCA TGCCTAGGTA AAGTTGATCC CTAAGCCACA GTTCCCAGAA GTTCCTGATT CAAAAGCAAA TTTTCTCTAA GGTCAAAGGG CAAACTGATT ATTCTAAATT CTAAACTGAT

TATTTCTAAA TTGAGAAAGC TTCAGGGAGA GATCCCAATA TTCGAAGGAT AAGAGAAATG AGGAGTGGAA GAGATAGGTG AGTAACAGTA ACTTAAATGT AGACTATATA TAATATATAA TATATGTAGA GTATATATAT ATAATTACAA TATATTATAT ATGTGGAATA TATATATTAT TTATATATAT TTATATATTT TATATATATA GATATTTTTA TATTTTATAT ATAAATATAG ATATTTTTAT ATTTTATATA TAAATATAGA TATTTTTATA TATATTATAT ATAAATATAT GTAAAATACT GTGAAAGAAG AATAGAATCT TGAGACCTCA AATTCACTAT GCCAAAGGGA AAGTTAAGCT TGGGAAATGA GTCATGCAAA AACTGCCTTC CTTTTGTTCC CAAATACCTG TAATTTCACA TGCTTACTTT ATCTTATATA AAATGTAGAT GTACTGAGCA TGAGATCCAT GCATAATTTC CCTCTAGTCC CTTCTTTTTA CATGTAAAGT GTAGACTCAC TGAGTGTTAC AGAGCCTTGC

CACAATGTAA ACACTTGTCT CATTGCCAAC CCATCTTTCG TTTATTTTCT TCCCCTCCTG CTTGCTCTTT CCCCTCTAAA GATGGAAGTT CCCAAAACTC TCTTTGGAAA AAGCGCAGGT CACAGATCCT ACAGTGATTT GTGTTTCTTT TACCTGGGAC AAAATAAACC TCTAATCTGT TGAGATATGC TTCAGTTACT TTTTGGTTTA CAATATGTAC ATGTATGTAT ATAATTTATA TGTATATAAT ATATGTACTT GTTTTAACCA GAGGTATGTT ATTCAAAATC CATTCATCCT TACAATTACC TGCATTCTCC CACAGTATTT TCTGTGTCCC TGCCCCCGAG GTTGTCACTG CAAATCAGGT ACATGGATAC TGGGAGCTGA TGGGCTCCCC TCTGGCTACC TGGGCTGCTG AAGGGGCCAT AGACAGACCC AGCTTTCCTC TCGTGGAGAG GCCCTGGGCC AGCGCTGCGT GGGAGTGGGA TTACAACCAG ACTATAGCTT CTTCACCTGC TTTTTCCTAT CAGGATTTCA TAAGAGGCAA

TTGCTTGTTT TTTGAGGGTG GGGGCAAATC AGGGGGAGTT GAAGAGGAAA TTGGGTAAGA TTTGAATAGT TGGGCATGTT GAATATTATG AATATCATCT CCCTCTTCAA

ATAATCCAAA ATATACCCCC AAGAAACAGG CTGATTAGAG GTGCTTCAAG GCTCCACTGA ATCTCCCAAG CTCTGAAGAT GTAGCTAGCT GTTACCGGAT TGCCGGTTTT

CAAGCCTCGC CTCACATGGA CCCTCTTGGC AGTTTCTCGC ATGGGGGAAG CATCCGCTAC A AGATGGGA ATGAAAAGAG GAAAGAAGAC GGTGCAAACT CAGGCACACC

_ CCGGTGTCTG CCACCAGTGC TATTTAATCT CTGAGGTGTC ACCCTTCCTG GCTTTATTGT CTCTTCCTGG AAGTCTCTTG TCCTCTCCTC CACACCCTTT AATCAGGCAT ' CAAAGACTTT AACCAGTTTT GCTGTGTGCC CAGGCCCACT CATTCTCACT TTTATGGCAA AGGGAGTGGG AGACAGAGAG ATAGCCAGAA AGAAGAGATT GGGGACCCCA AGACAAATGT TAGAATTTTA ACCAAGGCCA CCCTGTGGAC AGGAGATTAT TGGGTTTAGT GGAAAGCAGC ACTGGCCACA ACCACACGTG GCAAAAGCAT CTATCGAGGA GTGAAGTTAT ATTTGGTGAA TGTGACCGGG AAGCAGGGGC AGTGGTGTCC TCCTGCCTTC CTGAGGCACT CTGTTCCCTT ACCTCTGCGA AGGCTTATTT TACCCCTGAG TGCTTAGTTT TGAAAGCCTT AGTTCCCTCT CTCCCATAAA AAAGCTCTAC TCTGCTAACA TCTAAGTTAC CTTTGCAGAG TCTTAGGTAG AGGGAGGAAA TCCCAATAAA GATTCCACCC TATCTGCAAA ATACAAACAT GGTATTTCTT GCATTCCCAA AATTGTGAAA GAAAATGTGT ATCACCACAG TAGAGAATGG CATTTTTTGT TTGATCAAAA CCTAAATATA TTTGATGAAA ATGTGTCTGG TTCTAAGTTT ATTTCCCAGA AAGCCATGTT TACTCACTTG GAATTTATAG ACATCTTATA ATATCTGAGT CGAGTAGGAG

CTCCGGGCTC TACCTCACTC TTTTCTCCCA CACCCAGGGG GAAGTGTAGG GTTCTCAGAC TTTAGAATAA AGAGGAATCA CCTGGACAAC TCACCTAAAA TGCACATCTT CAGGTCTCAT ACTCAGAGGC TCTGACTCAA CAGGTCTGGG TGGCGCCCAA GAATTTGGGC TTTAAATGAG TATCTCAGAT GATTCTAATA CAGAATGTGT AAGATGACCA GATCCTATCA CACTTAGATG TATTGGCCTA GGGCCACCTA ACTTGGAGAA AATGTTAGTA AGACCCCGTG GTTGGTGCTC AGCTATAGGT ACCAGAATTT TGATCAAAAT TTACTATCAT TGTGACACTT CTCTTCGGAA CTGGAAGGCC AGAACCCCAC TTGTAAAGTG CTGGGAAAAT ACAAGGAAAA TTTAGGGTGA GTAGCATTTT GAATTCTTAC ACATGGAAAG TAAATGTATA AGAATTCTTA CCAATAAAAA AAAAGCAAGA GAGAATAGCT GCTAAAGAAT TAACACAAAT ATGTATATAT TAGTTATTCT CTTTTCTCCT

CTGATTCCAG AGGACTTTGT AATTCCACTA ATTCTTCTTG AGCTTCCAGG ATGATCTGAG ACTTGAATTT TTCATGTGCT TTTTGCTTCC TATTTGGCAG CATCTTATCT TGAAGTTTCC GCTTTCTGCT TGGGGACCTA AAAACTAACT AATGGGAATT TCTTCAAAAT GAGCAAACTC TGGTGAATTC CCAAAGCGGA AGAAACAAGT GAGGATCGGG CTGGTTAATT AAGAGAACTT TTCCTGAATG TAGCCAGACT GTTTGCCGAC TGTTGTTAAC ATGAGGGAAG AAATACCCCT GGATTTTAGA AGAGCCCCTT GTTTGTTTTC CTTGGCCATT TGTGCTGCTT GTTTTGTAAG TCAGAAATTT CCTGAAGGAC TATTATTAGC TTTGTTCTCA CGTCAGAAAA CTTCTGCTCT GGCCACTTTT AAACATATAA CTTGGATTTT ACTGTATTAG AAAATGTAAC AATTACAGAC AGCACTAAAA GGACACCAAA GGGCAAAGAA AATGGGTAAC TTTTTTTTCT TCCCCAAATC TAAAATAGGT

GATTTTGGAG AAGTAGGAGA AAAACCTGGA TTTTCTAGAT CTCTTTAGAG CTCAACAACT GATATAGTTA ATTATGTAAG TCTTTGATAT TTGGAAATGA TTGGATTAAC CGGATAAC AA TGAATATTTA AATACAGTGA TTTGGCCAGG AGCAGTGGCT CATGCCTGTA ATCCCAGCAT TTGGGGAGGC TGAGGCGGGT GGATCACCTA AGGCCGGGAG TTCCAGACCA GCCTGGCCAA CATGGTGAAA CCCCATCTCT ACTAAAAATA CAAAATTAGC CAGGCGTGGT GGTGCAAGAC TGTAATCCCA GCAACTCGGG AGGCTGAGGC AGGAGAATTG CTTGAACCCG GGAGGCAGAG GTTGCAGTGA GCCAAGATCA CGCCATTGCA CTCCAGCCTG GGCAACAAGA GCGAAATTCC ATCTCAATAA ATAAATAAAT AAATACAGTG ATTTAACACA AGAGATTTCT ATTTCACACT AATGAGCTCT GTCACTGGGG CAAGCTTCTT TGCCTCATTA AGTCTCAGAT TTCCCGAGAG CTTATTTATT

TATACCAAGA GTGCTTTACT ACCGTCTCTG CTAGCTGTGA CATAATATGA CAAAAGGTAT AAATATGGGA AAAGGCACTA ATTTATATCA AAGCGTTCTT CGTTTTTCCT TGCTGTGAAG TTTTTAGCTA ATAATTCATA AGAATATACC ATATTTAGAG TGTTTACTAT GCATGGGCCT GGCACTTCAC ATACATTGCT TCTTACAAAT TTTACAAAGT GAAAGGTAGA TATTAATCTC ATTTTATGGA GGACAAGATA GAGATCTGGA GAGGTTACAT AACTTGCCAG TGTTTTTTCA GTTAATAAAT GGTAGGGTGG AGATTCAATC TGTGTTACTC TAAAGTCCGT GTCCTTTTTA TTGGCTCCAT GCCTACTCAG ATTTAAATCT CAGCAGGGAA GTAAACCTTA GTTTTTACAT GAGAAAATGT TACAGCAGCC TTCTCGGCTT CCTTTACCCC CATCCCAGTT TCACGAGCTT AGTGCCTTAG ATCGGGTTCC TTTAGAAGCA GACCTCGAAA TAAGGATGTG GGTGCCAGTC ATTTATTGAA AAGATGATCC CAAGAAAGCC TAGTAGGAGA GTGAGGAAGT GAGATGGGGA AAGGAAGAAA CTCCACAAGA AGTGTGTTAA TAAGCAGGTT ACCGCTGTGG GCAGCCATGG GGCTCAGCTG CACTAACAAA CTCTGTCTAG TACAGAAAAC CTCAGGGTCT CCCCAAGGAG GGGCAAGAAG TCTGCCTAGG GTATATATCC GCCAACTCAG TCACTGGCTG AGAGCTGATC CTGGGAGGGC ATGGTTAATT CCTCTGCACT TTCAAGTGGA TTCCTGTGGT CAGAAAAAGC CCTCTACAAT GAATTCCAGA TGCTTGTATT TAAATCTGAC ATGATCTGAA TGCTGTGTTG GGACAGGGTG GGCGTTATTA GTTTTCTGTC ATTACTGTAA CAGATTACTA CAAACCTGAT GGCTGCAAAC AACACATATT

TATTATGTCA TAGTTTGTGT GGGTCAGAAG TACAGGTTAG CTCAACTAGT TTCTCTGCTC TAGGTTTCAC ATTGCCAATA TCAAGGTGTC ATCCAGTTGG GCTCTTCTTG GGAGGCTTGG GGATGAATCC ACTTTCAAGC TCATTCAGAT TGTTGGCAGA ATCCAGTTCC TTGTGGTTGC AGGACCAAGG TCCCTGTTGC CTTGCTGGCT GTTGGCCAGG AGTCATTCTT AGCTTCTAGA GACTACCTGT ACTCTCTGAC TCGTGTCTCC ACTTCACCTT TCAAACCAGC AGCGGCTAGT CGAGTCCCTC TCTTCAAATG TCTCCAACTG TGCCTTCACC TCATTTCTCC TCTGTGTACC ATGTCTGCCT CTACTGCTTG TAAGGGCTCA TGGGATTACA TTGGATTTAT TCAATCCAGG ATAATCTCCA TATTTTAAGG CTAGCTGACT AGTGATCTTA ATTCCATCTA CAAAGTCCCT TCCAATAGTA CTGTATTAGT CCATTTTCAT GCTACTGATA AAGACATACC CAAGACTGGG CAATTCACAA

AAGAAAGAGG TTTAATTAGA TTTACAGTTC CACATOGCTG GGGAAGCCTC ACAATCATGG CAGAAGTCAA GGAAGAGCAA GTCATGTCTT ACATAGATGG CAGCAGGCAA AGAGAGAGAG CTTGTGCAGG GAACTCCTCT TTTTAAAACC ATCAGATGTC ATAATACTTA TTCACTATCA CAAGAACAGC ATGGGAAAGT CTTGCCCCCA TGATTCAATT ACTCCCACCA GGTCCCTCCC ACAACATGCA GGAATTCAAG ATGAGATTTG TGTGGGGACA CAGCCAAACC ATATCAAGTA CCTAGATTCA TGTTTGATTA AACAACCAGG GAGCAGAAAT CTTCAGGAGT GGGGGGCATC TTTAGAATTC TGCCCACCAA GGCTGGGCGC GGTGGCTCAC ACCTGTAATC CCAGCACTTT GGGAGGCCAA GGTGGGTGGA TCATGAGGTC AAGAGATCGA GACCACCCTG GCCATGGTGA AACCCCATTT CTACTAAAAA TACAAAAATT AGCCAGGTAT GGTGGTGGGC ACCTGTAGTC CCAGCTACTC

AGGAGGCTGA GGTAGGAGAA TCACTTGAAC CCAGGAAGCG GAGGTTGCAG TGAGCCAAGA TTGCGCCGCT GCACTCCAGC CTGGGAGACA GAGCAAGACT GTCTCAAAAA AAAAGAATTC TGCCCATCAT AGTAGGCTGT CCTACAGAGA CATAACCCAG GAATTAGGTG AATGGCTAAC CTAAATTAGC ACTGTGATGT GTTTTCTGAC TTGGTCCTTA TAGCTCCTCT GCTTAGATGT GGAACTAATC CATGAATGCA AGGGTTTGTC TAGAGTTTTA AGTGGGAGTT AAATATCCAA AGTACAGGAG ATATTATGGG TGCCTCATCC ATGTCCCCTT GGCATTTATC TTTCTTGGAT AACCCAACTC TATTAGTTTT TATATCTCAC TTGTTCCTAT ACTCTGTGAA CTGATGTCCC ATAAATAGAC ATTTCATTTT GCCAGTCTTC TTGAACAATA ATTACGATTA TTAATCTAGC AGTTATCATT AATTGGCCAC TTCACATTAG ACACAGCACT TAGGACTTAA GAATACCATG

TCATTTGATC ATCATAATAT GGTCAGGAAT TAAGTATTGC TATCCAAATT TTACAAAGAA GGCACTGAGG GTTAGAGTTT AAATAACTTG CTTAAGATGT CATAGCCTGT AAGTGACAAA ACTAGGACTC AAATACAGGT CCATCTGACT CCAAAGTCTA TGTTCTTGGC TACCACACTG CCTCTCCTAC AAGTGACCTG TGGTTTTACT ACTATATTCA CACTCTACTA ACTTTACCAT CTGCCATGAG TCTGTCTAGA GGAGGGCACA CACAGCACAG AAAACACATG AATGCAAAAT AAGGAAGGGC CTACTTACTA CACAGAGCCA TTCTAATACC TGATGTTTGC TCTAATCCAG TTTTACTATT AATTAGTTGC TGGTGCCCAA GTTTTTACTG AGAAATGGGG ATAATTTTGG AAGTCATAAT GATGCCTTCT TCTCATAGGG TATTTTATTT GTTGTTGTAT CTCCAGGCCC CAACACAGCC TGGCTTTTAG TAAATGATCA AAAATACCTG TTGAATGAAT AAATGGAGTC ACCTGAAACA

TGTTAAACAT TTGTTCATGT GTCCTAATCG TGGATTTCAG GATAGTAAGC ATCCTAAAAG GAAAGCATGC ACACTGTTCT TGCTACATTA ATTTCTCACA ATATAAAAAA AGAAAAGCAT CTGAAAAAAG CTGCCAGCCG CTGTGTCTCC TAATATCAAA CTGAGCACAG ATATGGAGAA GCTAAGGGAG AGGGATGATG GGCCATGCCT CTAACCTCAT CATGGCAAAA GTCCTGGGGG TCAGACCCGA GGAGAGCAGG AAGTGTCTTT TGAGGGATAC ATTTCCACAG TGGAAATAAT GAGACTTAAA TAAATATTAT ATACACAGTT CAACTGTTTT TATGTGTAAA GGTAGTAGGT TTTCACAGTA AGGAAGCACT TCTTTTTTTT TTTGTTTGAG ACAGAGTCTC GCTCTGTCTC CCAGCCTGGA GTACAGTGGT GCTATCTCGG CTCACTGCAA TCTCTGCCTC CTGGATTCAA GTGATTCTCC TGCCTCAGCC TCCCGAGTAG CTGGGACAAC AGGTGTGTGC CATTACACCT GGCTAATTTT

TGTATTTTTA GCAGAGATGC GGTTTCACCA TGTTGGCCAG GCTGATCTCG AACTCCTGAC CTCAGGTGTT CTGCCCGCCT CTGCCTCCCA ATGTGCTGGG ATTACAGGCA TGAGCCACTG CACTCACCAA GCACTTCTAC TGATAGCATT TACAAACCCT TCTTAGAATA TTTAAAAATT CTAAGAGAAG AGTAAATTGA GGCTTCCCAA CTAATACTAG GAGGTTATAA CCTTCATACC AAAACTGGAC AATGCTTGCA CAAAAGAAGG AAGCCAATGA GGCCACCTAG AAGGAAGACT GGGCATTGGG CCCAGTGAGT CCTGGAAACC TCATCTGTGC CAGCCACCCC GGCATGGCCT GTATGAGTGG ATGAGGGTGA CTTGTCCACA GACAATAGCC ATCTAGCTGT GATAAAGGAG TCAAGGTAGT CAGCTGCATC TCTTTCACCT GTTTGCCAAT GTTACACAGG TTGAAAAGCT AAGGTTTATG TAAAGCAAGC ATCAAAGATG ATGAAATGAT CAACCTGACA ATGAGTACTA

TGCTGCATTG TCCAGAAAGG AACTGTGGAA GATTTTGGGC TGAATTTCAA AACAGAATTT CCTCACTCTC TGGATGTTGG CTTACTTGGC CTTTGATGTT CAGAGGTGGT GCCTTTGTGT TGTTGAACAA TGTTGATTTT GGAGAGAAAA CAGAGTTGAA AAACCCACAA GTCATTCCCT GGGGAGTATT ACCGGAATAC AGAGGATAAT TTCAGCAAGC CAGCAAGGCC TCATCTCTGC TTCTAATAGA TAGGAAGAAA GGAAGAGAGG AACAATACTT TTTTAAGAAG CTCAGCTTTA TCGCCTTATC TCATAGAAAG ATGCCTCCAG TCTGTCTGGC TAAAGGTAAT TGGCATGGGA AAGTCTTTAT CTGTGATTCT AACAAGTGGA ATGTTTCCCT TCATTAAGAG AGCCTTGTCT GGCTTGGGGA AATGAAACAC TTTCTCCGAT ATGAGTGGGC TGTAACCCCT GCTACTAAAT ACTCAGAAGA AATAAGGCGG TTGTGGAGCA GTCAGGAATG AGTCACTTGC CTCCCTGGAA TATTCAGAAA

ACTGAATCAA AAGTACATTC TTCTGGGTTT TCTTAGTCTA ATAGACTAAG GGTCTCTACT TTGTTAAATT TCTGGGAAAC AGCATAGAAT GGGAGAAAAA ACTGGTCACT GTAGTCATGC AAATCTGCAA AACAAACAAA AAAGTCTGGG TATTGCTGCT AACTAGCTAT GTGACCTTAA GCAAGGTATT AACTCTCTCT GAATTTCAGG TTCTTCATCT GTTAAATAGC ATATCTGTAA AATGGGAATT ATTTTCATAT CATAATGCTG TAGCTTTAAA AAATAAAATA AAATGGATGA GATAATCAGA ATTAAAGAGC CTGGGATATA TAGTTAATAT ATAGCAGCAT GTAAAGATCC TGTTAGAAAT GCTAATTTTA CAGTTAACCA TTTGGAGATG ATCCGCCAAA GCTGCTAGTG TAGAGGCAAC TGAGAATTTG CCTGTCCTTC AGAATATGAA TAAATAACTG TCAATGATGT CTCAAGCCTA GAAAAACCTA TCCATCTGGA TGGGTGGGAA ATTTCTAGGC TAGTATTGAG AAGCCCATTT

CTTGGGAAAT AGGTCCTGGA CTGAGTGAAG GAAAAGAAAC AGTAAAACCC ATGGTAAAGC AGCAAGGCTC TCTAGAGGCT CTGGAGAGGA TGAATTGAAT TCTAGAAGAT GAAGTAGGGA AGACGCTTTA CCTTCTTGTG AAATGGATTC AAAGATTCAA AGACCTTCGG GAATCTCCAA TTGTATAAAT GGCACCATAG CTGTATGTTC CATGGAACAC TACTTCCCAG AGATGCCCAG TGAAAAAAGA ATGCCACAGT CAAATAAGTT TGGAAACACT CCATTATGTG GCCACCTCCT TGAAGACTCT AATGCACATT AGCATGTTAA ACAGTCTTGA GAAGTCCTGC AGAGCAGAAA TTGCTTCACA TCTGCTAAGC CGGCAGTTTC CCAATATACT TGATTATGGA TAGTTTTTTC CTTACAACAC CATTCTCTGA TATGCTTCCA ATGACATGAA ATAAATATAT ATGCATGAGG TTCTTCATTA GGGCATACTT TTTAATAGAA AATATTGAGA ATAATCTAAA TATAAATGCA

CAGCATTTAC CTTTTCTGCA TAAACTATAT ACAGGCATAC CTTGGAGATA CTATGGGTTT GGTTCCCAGA ATATCTCCAA AACCACATTC GGTTTTATGA CCACTGCCAT AAAACCAGCC ACATGAATTT TTTGGTTTCC CAATGTATAT CAAAGTTACA TTTTTACTAT ACCATAGTCT ATTATATATA CAATAGCATT ATATCTAAAA AACAACGTAA ACACCTTAAT TTAAGGCTGT GGCTGGTTTG ATTTTCTACC CAGACCACTA AAACTTTCTT CATATCAGCA ATAAGGCTGT TTCACTTTCT TACTATTTTT TGTGATAGCA CTTTTCCTTT CCTTCAAGAA TTTTTCCTTT CTATTCACAA TTTGTTTGAT ACAAGAGGAC TAGATTTTAG CTTATCTCAG TTTAAGGTGT TTACATTGTT AGCTAAAAAT GCTAATGATC ATCTGAGACT TCAGCAAGTC ATAATCTTTT GCTGGTGGAA GGTCTTGCCT CAGTGTTGAT GTCTGCTGAC TGGGTGGCTT TGGCAATTTC TTAAAGTAAG

ACAACAATCA AGTTTGACAT ATCAATTGAC CCTTCCTGTC ATAAATGATT TTTTTTTTCT CTGTAGCCTG CAATGCTCTT TGATAGCATT TTACCCACAG TAGAATTTTC AAAATTGGAG TCAATCCTTT CAAACTCTGG TGCTGTTTTA TCAACTAAGT TTATGGAGTA TTAGAAATCC CTTGTTGTCA TTTCAACAAT GTTCACACCA TCTTCCCCAG GAGTATATTC TACCTCAAGA AACCACTTTC TTTGCTCATC TATAAGAAGC AGCTCCTCAT CCACTAAAGT TTTATCCTGA GATTGCAACA ATTCAGTTAC ATCTTCAGGC TCTACTTCTA ATTCTAGTTC TCTTGCTGTT TCTATCTCAT TTGTGCTTAC TTTCTCCGCT GAAGTCTTGA ACCCCTTAAA GTCACTCATG AGGGTTGGAA TCAACTTCTT ACAAACTCCT GTTGATGTTG ATATTTTGAC CTGCTCCCAT GATTCATGGG TATTCTTAAT GGCATCTAGA ATGGTGAACG TTTTCAGAAG GTTTTCAGTT GGCTTTGCCC

GGATCCATCA GACGAATCCC TATCTATGGA AGCTATAGAT TTATAAAATG TATTTCTTTT TTTGTGGGGG CATAGCGTCT CACCCTGTCA CCCAACCTGG AATGCAGTGG CACAGTCATA ACTCACTGAA GACTCAAACT CCTGGGCTCA AGTGATTCTT CCACCTTGGC CTCCCAAAAC ACTGGATTAC AAGCTTGAGC CACTGTGTCT AGCCCAAAAT GTATATCATA ACTAATGAGG CTTGAAAGTC AAAGTGACTC CTTGATCCAT GGGCTACAGA ATGGACGCTG GGTTACCAGA CATGAAAACA ATACTCATCT CCTCATACAT CTCCTTCAGA GCTCCTGGGT GAGCAGGCCC ATTGTCAAAT GAGCAGTAGT ATCTTGAAAG AAATTTTTTT TCTGAGCAGT AGATCTCCAC AGTGGACTTA AAATAGTCAG TAAACTATGC TGTAAACAGA AGTGCTGTCA TCCAAGCTCT GTTTTTCCAC TGATAGGGCA AAAGCAGAGT AGATTTGGCA TAATTCTCTA GGGCCTTAGG ATTTTTGGAA

TGGCAAATTG AGCATTGGCT TCAACTTTTT χχ_TTTTχχχχ xxxxxxxGAG ACAGAGTCTT GGTCTGTCAC CCAGGCTGGA GTGCAGTGGT GCAATCTCGG CCCACTGCAA GCTCTGCCTC CTAGGTTCAC ACCATTCTCC TGCCTCTGCC TCCTGAGTAG CTGGGACTAC AGGCACCCGC CACCATGCCC GGCTAATTTT TTGTATTTTA GTACAGACGG GGTTTCGCCA TGTTAGCCAG GATGGTCTCG ATCTCCTGAC CTCGTGATCC ACCCGCCTCG GCCTCCCAAA GTGCTGGGAT TACAGGCGTG AGCCACAGCG CCCAGCCTGT CTTCAACTTA AAGTCGCCAG CTGTGTTAGC CTCTAATAAG AGAGTCTGCC TGTCCTTTCA AGCTTTGAAG CCAGGCATCA TTCTCTTCTC TAGCTATGAA AATCTTAGAT AGCATCTTCT CCCAATAGGA AGCCATTTTT TATGCCCTAA AAATCTGTCG TTTGGTGTAG CCACCTTCAT CATTGATCTT ACCTAGATCC GCTGGATAAC TTACCACAGT

GTCTACATCA TTACTTCTGC TTCACCTTGC ACTTTTATGT TATGGGGATG GCTCCTTTCC TCTAACCTCA TAAACTAACC TCCACTAGCC TCACATTCTT CTTTTACAGC TTCCTCGCCT CTCTCAGAGT TCACAGAATT GAAGAATGTT GGGCCTTGGA TTACACTTTG GTTTAAGGGA ATGCTGTGGC TGGTTTGATT TTCTATCCAG AACACTAAAA CTTTCTTCAT ATCAGCAATA AGACTGTTTC ACTTTCTTAC TATTTTTTGT GATAGCACTT TTCCTTTCCT TCAAGAATTT TTCCTTTCTA TTCACAATTT GACCGTTTGA TATGAGAGGC CTAGATTTTA GCCAATCTCA GTTTACACCA TGCCTTTTTC ACTAAGCTTC ATCATTTTAG CTTTTTATTT AAAGTAAGAT GTGTGACCCT TCCTTTCATT TGAACACTTA CATGATGATG CCTGGCTTCA AAGCTTGAAA GGACAGGCAG ACTCTCTTAT TAGGGGCTAA CACAGCTGGC GACTTTTAAG TTGAAGCCAA TGCTCAATTT

GCCATTAGAA GCCATTGTAG GGTTAATTAA TTTGCCTAAT TTTAATATTA TGGTGTCTCA GGGAATAAGG AGGCCTGAGT AGAGGGAGGG AGATGGGGAA ACAGCCAGTC ATCAGAGCAC ACACAACATT TATCAATTAA GTTTATCACC TTGAGGGCAC AGGTCATGAT ACTTCAAAAC AATTACAATA ATAAAATAAA AAATCATTGA TCGCAGATCA CCATAACAGA TATAATGATA ATGAAAAATT TGAAGTATTG TGAGAATTAC CAAAACGTGA CACACAGACA CAAAGTGAGC ACATGTCATT GGAAAAGTGG TGCTGATAGA CTTACTTCAT GCAGGGTTGC CACAAATACT CAATCTGTAA AAAATTCAAT TATCTACATA GTACCATAAA AACAAGGTAT ACCTGTTTAT ATAATCAAGA CCAACAGAAC CCTAGAGAAA ATAGCTCACT CCCTAGCTCG GAGACATTCT AACCAACATA CACTTACCTT TCTTTTTGCT GTGTACAGAA TTCAAATCCC TGTCTCAGCA AAATTGCAAA

GTATCAAATG TCATGTCCAT CTAATACTCA AAACTGCAAA TGTTAAGTCT TGTAAGCCCA GAGACCACTG TATATACAAG TGTTGCTATA AGCATTAGTT CTTCTCCAAA GAAAATAGTC CACTTGGTAG AAACAAACAA AAAGAAAAAA AAAGAAAGAA AAAACATTTT TTACAAGAAG ATTCAGTCTC TTACCTACAT AAGCAAAAAT ATGAGATGTT CTCTTATCAT TTTTCCATCT ATCTTATAAT CTTTGGTGCT GACTTAGACA CTCATTTTCC TTTTTGTACG TGACCATGTA AAAGTTCAAG TCAAGAAAAA CTTGTTTTGA CATTTGTTTT GCTGAGTGAT GGGTCCCTAA AAGAAATTTG GCTTTGCTTT TGAAAAGTTC AGCATGATAT TGTGTGAATT TTTCATGGCT AATGATTTTT AGAACAGTTG TGATGTGTTT AGGTGTTTTA AGAATATGAA GCATTCAGTG GTTTAAGTTG GTTGTTATAA AATGAAAGAA TATGAAGGAA AGCCTTCTTG TCTTAGAACA CACTGATTCA

CAAATAAGCA GCTTCTCTCA AAATGTTGTA ATTACAAAAA TTCCAAGGCA AATATAATAA ACTCCTTGTC GGTGCTATGT CTAGAAACTT AACAGCCCCA AAGAAAGTCC TGACAAGGCA AAAAATATAT ATATATATAC AAATTGTGGA AGCAGGGTGT TGAAAGAAGA ATAAAGACTA TATAAGGACA AACTGTTTAA AAGGGAGGGT ATCCTTGAAA GCTTGACACT TGACTCTTTT GACGAGGCTG AGGGAAAACA CTCAGTTTCA TAGATTGCTG GTACGGATGT AAAATAGTGA CATCCCTATA GAGAGGAATT TGGCAATATC TAGCAAAAGT GCTTATGCAT TTATTCTTTG ACCTAGTAAT CCCGCTTCTA GGATTAGTGG TGAAGATACA CCTCAACAAT AAAAATATAT ATACATTAGG TTATTAGTTA TGGTTTAATT TTTAATAGCA AAATATTTAA AACAACCTAC ATGAACAAAT AGGAGACTTA CTGAATAAAC TATGGTATAT CTGTACAATA AAGTGCAATT

CACTTATGTT GTTAATTTGT TCCAAAAATC CAGAGCCAAA GAGTATTTGT TATGCTCTCT TTAGTATAAG AAAGGGGAAA TAAGATATGT GTGCATCTGT TTATTTTTGT GAAAATAAGT ACAGAAAGGA TAAGTAAGAA ACTAGTAAAA CTAGTTATCT CCTAGTGTTA GTAGAAATAG AATGAAAGTG AATTAGGCTT CTTTGAGTAT ATGTTTATAT ATAGTTTTGA CTTTTGAATT ATGTTTATGT TTACATAGTC AAAAATATAA ATTAATCAAC AGAAATAACA AAAAAAGAAG AAATCACAAG CTTTAAAATT TAATACAAAC AGAAATAATT GAATCTAACA GTATATCAAA GTGATAACGT AAACTCAGAA GAAAAAAACA TAATCCAACA TACCAGTGGA ACACAATATT CTAACTGTAT ACATTCAGTG GTTATAGTCT AAGGACAAGA AAAATTGCAA AAATATCTTG AACTTTAGCT TGTAGGATTT TTATTGGTAG CAATACTAAT GTACTAATTC TGAAATTAAT GTTCGTGTAT

TATAGAATTG AGTAAATGAA TAAATATGTT GATGTTATTG GGAACTAAAA TTATCATTCT GGGAGTAGAG AAATATAAAT ATGGACTTGG CAAATGAAAC AAAGACCTGC AGAGAGATAA CCATATAAAC TCATTATTTT AAAAATTATA AGTGTCCTAG CTCTGTTACT GAAAAGGCCT AGATTCAATC TTATCTTGAT AGACAGGAGG GCACCCCTTT CTCAGAACAT GGTTTCCAAA TGCCATTCTC CATTAAAAGG AACAAGGTCT TCTTGGAGAA AAGACTGATT CTAGGTCTGG ATTAGGTAAA GTACAACGTT AGTCTGGAAT TTCTTGCTGA ATCAGAAGTA AGAAAGTGCT CAAAAACATG GGAACATGTC ACAAACACAC GTGAGGCAAC TTGAATCCTC ACTGGCCATA TTTAGGACAA TCGAGCATCA AAAAAAAAAA AAATGTTGAG AATAATGGAT TCTAACACTT AAAACAAAAA ATAATCCATA GCCCACAGAA GGGGAAGAGA GGGGGAGCTC TTATTTACAG ATGAATATCA AATAGCAAAG ACAGAAGAAA TGACAGAATT AGAGAAACAT CATTTTGCAA AACACCACTG TAATAATCAA TTCAGGCAAG TATTATTAAT GGATGTATTA CTATTGCGTA AAACCAGTTG GGGAACAGGA TATTCATACA GTCTGAAGGT GTCACCCTAA ACATAACTTA TTACAAGTGG AAAATGGTGC CTTTACAATG AAGAAATCTA GCAGAAACCA TCTTAATCTA GTGATCAAAC TTAGTATCAC CAATAATGGA TCATACTGAG TCATGTGTCT CCTAATATGA TGCACCAGGA AGGATGCAAC GTCATGAACG TTGTATTCTT TTGTATTCAA CAGACCACCC AGGGTAAAGG CAGCTTTCTC ACTTACTAAT CAGAATTGTT GGTTTTAATT CATTTTGGAT TTTAAGATTT CTTACTTTCT

TGTCAGCTCA GAAATTTATT TAAGATGATT TTTATCTTTT ATTCAATACT TTAGCTTGGA GAACCATTCA GAGTTTCTAA CTCATTGTAT TGCCAAAAAT AGAAAACAGC ATGGTTTCTT TTGAAAATGT CTAACTTTAA AGTTACTTGT GTGTGTCACT CAGATTCACA TAGCTTTTTT GCCTAGTAAT GTAGTATCAT GTGGCAAGGC TATAAAAATG TTTACAATCT TTTATTTAAT ATGACTCTTG AGAGTTTATT CTAAGGAAAT AATTGAATAG TAACAAAACA CTATTAACAC AAAGCATAGC AATTTGATTT GGGCAACCAA ACACTGGAAA CAACCTAAAT GTCCATTACA GGAATCATTT ATGAAGCAAA CACTAAAATA TTTATTGTGA AGATTATGAG AACATAGAAG ACAGTTATGA GAGTAAATTT GAAAACCTGA ACACAAAACT TACATATACT CCAATTGTAA CTTATAAAAA ATACGTGCAT ATAAGGATAA AACAGTACAA ACAAAAAAAT AGTTGCGTTA GATTGGTAGA

ATTATGGCTC CTTTTGCTGT CTTAATTTTT TCCTTTTACA TTTTGATACA TTATTTTAAT TTTAATTTTA AAATTCAAAA GAATTTGCCA CTCATCTTTG CCACTTCAAG GAAAAAAGAA ATGTGTTCGA TTATTCTGTT CTTAGTATAG TTTTGGCAAT TTCCTCACGT GTAAAAAGAG AATACTATTA ATAATTTCAG TATCTATAAG ACAATATAAA ATTAAAGAAT CTAGCCCAGT AACTGGTACA TGGAACGTAA TTAATAAATC ATTATGGACT TTTTTTCTCA CACCCAAGTA GGGAGGAATC AGTGGTCCCC TAGAGGCCCA GTGTAGAGGT GGCAGCACCA ATCCCTAGGG GAGAAGATCT TGGTGATGAT AATTCCTGAG CAGACAGTTA GCTGAGAATT CAAGAGCAGA AAAGTAAGAA AGAAACAACT TCTTGCTAAC ACCTTTCCAC CCACGTTTCC CTGTTCTGTT GTACTCTGCT TACCCTTTCA TGGATGGAGG CAGAGGAAAG AGAACCAAGT TTGCTCTTAG

TCATTCACTA TGTTGTTTAA TCTGCCTTCC ATCTTTCTTA TCAGTTCAAA TTAGAATGTA GACCTGAATT TAAATCCCCG TTCTGTCAGT TATAATGTGA CCCTAGAGAA AACACATTCT CTGAACCTCA GAGAACATTC TTCATTTGTA GAATGGGAAG ATTAATCTAT ATTCCACTTG GATGGCAAGT CTTTTATAAA CTTTATAACC TAAACATGTG TGAGTTGCTA GTATCATTAT GTTGGTAAAG TTATTCTGAG ATATGATAAC AGAACTGTTT TGTCTAACTC CACTAGCATG GTTCAGGTTT AGAGAGTGTG GAATTAAAAG GCTTTATCCT CAAATATGAC TTAAATCCGA TTTTTCTCAT CCACTTTCCT CCACAAACAA ATCCTCAGGA AATGACAAAC TTTACATGGT TAAACATCAG TTTTGTTTAG TCTTTGACAT CCACATGGTT AAATCATACA TTTGAAAACT GCTTATATTT GTGTTGTCTA TGTCTAAATT GAAAAGACTT ATTGAGGAAT AGAAGACTAC ACATTTTTCA

GCAAACACTG CACGTTTTGC AGAATTTCCC CAGGCACCAG TCTCCAGGAA TTTATTGGCT ACTAACAATA CTAAGATATG GATGAATGAG GAAATCAAAA TGGAGATCTT GCAAGTTTTG TGAGAATGGG TGAATGGTCC AAATGAAGAG ATAAGTTGTG AAATATTAGT ACAAGTAAAA ATTATTTACA ATGAAAGACA TTTTGTCAAT AGCTATGAGA ATTTTACCAT TGACCCAGAA ATTCCATTTC TTTCTTCAGA AATACCCACG TAGGTATACA TATAAAAAGT TATTCATTAC AGTATCGTTT TTCATAGGAA AAAGTTTTAA AAATCAGAAG CTATCTAAAC TATGGTATAT CTAGGTCATA GAAATCAAAT GACTAAAAAT GTTAATATAA GCATATGTTT TTAAATTAAC TTGGCTTGGG TCTTCAGCAA AATTGGCTTC TTAACATTGC ACTCCAGAGT TAGACTTACC CACTCAGTCA CTTATCATGC AGGAGCAGAC TCCTAATACC ACATATCATA GAGCAGAGTA GGACACAGGT

TCTCTGCAGG CAGGCAAATC CCAAAGAGAA GGGAGGAAAG GGCTGAGACA CTGCATGGTC AATTTCTTCT GAACTCTGCA ATGTACGGAG GTGGACAGTG TCCACAAAGA TTGCTCCCCT GGACCCACCA TCATAATAAC ACAACGGCTT TGTTTTGTTT TTGTTTTTGT TTTTTGACAC GGAGTTTTGC TCTTGTTGTC CAGGCTGGAG TGCAATGGTG TGATCTCGAC TCACCACAAC CTCCACTTCC TGGGTTCAAG TGATTCTCCT GCCTCAGCCT CCTGAGTGGA TGGGATTACA GGCATGCACC ACCATGCCCA GCTAATTTTG TATTTTTAGT AGAGACGAGG TTTCTCCACG TTGGCCAGGC TGGTCTCAAA CTCTTAACCT CAGGTGATCC ACCCGTCTTG GCCTCCCAAA GTGCTGCGAT TACAGGTGTG AGCCACCGCG CCCAGCCCAC AATGGCCTTT TGTTTACATC TCTAGTGCAG CACTCATTTC ATGTTCTTTC AAGAAGAATA CATATTTCAT CTTTTTATTT TATACAGCAA

TTAGCACAGT GCCTGGCATA AGGAAAATGA TCATTAAAAG CTGGGTGAAA AACCTAATAA AGCTACTGAG GATAGGAACT GCAGACCAGC ATGGAAAGAA AACTATGAGC CAGATATTGA CATCATCCTG AAAGGCAGAA GATTTAGTAT AGGCAAGAAG TATGCTTTTG GAATATAGAA AATCTGGATT ATGATAAGAA AAGAATCATA TTTGTCTTAT CTTACCTACT CACTTCTCAG TTCCACATGT TTCTGAGGCT GTTTGTCCTT ACTTTCTTTT CTGTTTTATC CACTCTTTCT GTTCTTTAGA TTGGATCATT CCTATTGAGC TGACATCAAG TTAACTGACC TTTTATTTTG TCCAAACTGC TGTTAAATGC ATCCAGTGAA TTTTTAACTT TATATAGTAT ATCTTTTAGT CCTAGAATTT CCACATGAGT TTTTTAAGTT TCCATTTCTC TGCTGAGATC TCCTATTTGT TCATTCATTA TGACCATATT TTTCTCTACA TTATTGAGCA TAATTATAAC AGCTCTTCTA

AAATTCTTGT CTGCACATTC TAACACCTGA ATTATTCTGG GGTCAGTCTC TGTTACATTG CCTTATTACA AAAACAGTAT AAGTCACATT GCCTTGTTTC TTAATATGCA AAATGATTTT TGATTGCAGA CTAGACATTT TGAATTAAAC ATTATAGAGA TTCTGGATTC TCGAGAGAGT ATTGACTTGT TTTTTCCATC AGGCAGGTAA CTTGACTGGA CTCAAACTCC AAACTCTAGG TCCTCTGTAA TGGGCAACTG CAGTAATCTT TGTTTAGTTC TTTAAGACTT ATTGGCCAGG CACGGGGGCT CATGCCTGCA ATCCCAGCAC TGTGGGAGGC CAAGGTGGGA GGATCACCTG AGGTCAGGAG TTCGAGACCA GCCTGGCCCA CATGGTGAAA CCCTGCCTCT ACTAAAAATA CAAAAATTAG CCGGGTGTGG TGGTGGGCGC CTGTAGTCCC AGCTACTCAG AAGGCTAAGG CAGAAGAATC ACTTGAACCT GGAAGGCAGA GGTTGCAGTG AGCCGAGATT GTGCCACTAT

ACTCCAGCCT GGGTGACAAA AGCGAGACTC CCTCTCAAAA AAAAATTTAT TGGCACTGCT TGGCATCTGC TATGAATACA TGAAGTTCAT GGGTCAGCTA TAGATCTGGG CACGTTATAC ACAGAATTTG GGTCTCCCTT TCTCTGGATT TCTCCTTTTC TGGATTTCTT TTCTCATTTT CCAGCAGCTG TGGTTGCCCT AAACTCGGTC CTCTGTTTCT TTACGGCAGT AAGATTTGGG AACTTTTAGG TTTTACCTGC CTCTCAGACA AAATAAAAAA TAATTTTCAT CTTGATGCTA CTCCTTTCTT CCAGATGTAG ACACCTCTCT AATTTCCAGT TGCTTTTTAT TGCTCTCCAG AGTCTAAAGA TTATCATTGT TTTCTGTGGG AGAGTTGGTC TGATAAAAAC TACTCCCCCA AAACTGGAAG CTGGAAGCTT GTAATTATGA ATAGACTTTG AGTAGTATTC TTCTTTGGAA AAGGATTTTA ACTACTCCCT ATGTACTTCT TTATTTCCTG TTTTTCTCAT CCGTAATCTT TTTATTTTCA

TACTTCCTAA GTCAGACAAT TTTCCTACTT GAAGATTCAG TGACTGCTAT CAAATGACCC CCATATTACT AAATACAATA TCCCCAACTG CATTTATAAA AAGAAAATTT ACTGTTTATT AGTAAACAAT GTTGTAGAAT AGTAAAATAT TGCTGGGCTT TGGAGCCAGA TAATCAAGGT TAGAATCCCA GATTCTAACT TACTAGCTGG TGTATTAGTC CTTTCTCATG CTGCTAATAA AGACATACCC CAGACTGGGA GACTGGGTAA TTTATGAAGA AAAGAGGTTT AATTGACTCA CAGTTCAGCA TGGCTGGGGA GGCCTTAGGA AACTTACAGT CATGGTGGCA GCAAGGAGAA GTTCCAAGCA AAGAGGGAAA AGCCCCTTAT AAAACCATCT GATCTTATGA GAACTCACTC ACTATCACGA GAACAGCATG AGGGTAACTG CCCTCACGTT TAATTACCTT CCACCAGTTC CCCCCCATGA CACATGGGGA TTATGAAAGC TATAATTCAA GATGAGATTT GGGTGGAGAA ATAGCCAAAC

CATATAATTC CACCCCTGGC CCCTCTCAAA TCTCATGTCC TCACATTTCA AAACTCAATC ATGCCCTCCC AACTGTCCCC CAAGGTCTTA ACTCATTCCA GCATTAAGTC AAAAATCCAA GTTCAAAGTC TCATCTGAGA CAAGGCAAGT CCCTTCTGCC TATGAGCCTA TAAAATCAAA AGCATGTTAG TTACTTCCTA GATACAGTGG GGGTACAGGC GTTGGGTAAA TACACTGATT CCAAATGGGA GAAATTGCCA AAACAAAAGA GTTACAGACC CCATGCAAGT CCAAAACCCA ATAGGGCAGT CATTAACATT AAAGTTCCAA AATGATCTCC TTTGACTTCA TGTCTCACAT CCAGGTCACA CTGATGCAAG AGGTGGGCTT CCAATGGCCT TGGGCAGCTC TGCCCCTGTG GCTTTGCAGG GTATAGCCTG CTTCCTGTTT GCTTTTTCAC AGGCTGACAT TGAGTGTCTG TGGCTTTTCC ATGAGTATGG TGCAAGCTGT TGGTGGATTT ACCATTCTGG GGTCTGGGCC AGGTGCAGTG

GCTCATGCCT GTAATCCCAG CACTTTGGGA GGCTGAGGTG GGGGATCACA AGGTCAGGAG ATCGAGACCA TCCTGGCTAA CACGGTAAAA CCCAGTCTCT GCTTAAAAAA TACAAAAAAT TAGCCAGGCG TGGTGGTGGG TGCCTGTAGT CCCAGATACT TGGGAGGCTG AGGCAGGAGA ATGGCGTGAA CCCAGGAGGT GGAGCTTGCA GCGAGCTGAG ATTGTGCCAC TGCACTCCAG CCTGGGCGAC AGAGCAAGAC TCCATCAAAA AAAAAAACAA AAAAACCATT CTGGGGTCTG GAGAATGGTA GCCCTTACAG CACCACCAGG CAGTGCCCCA GTGGGGACTC TGTGTGGGGG CTCTGACCCC ACATTTCCCT TCTGCACGGC CCTAGTAGAG GTTCTCCATG AGGGTTCTAC CCCTGCAGCA AACTTCTGCC TGGACATCCA GGCATTTCCA TACATCCTCG GAAATCTAAG CCGCGGAGGT TCCCAAACTT CAATTCTTGA CTCCTGTGCA CCCACAGGCT CAATACCACA

TGTAAGCCAC CAATGCTTGG TCAGGGCTTG AACCCTCTGA AGCAATGGCC TGAGCTGTAC GTTGACACCT TTTAGCCTAG ACATCTAGGA CACAGGGCAC CATGACCCGA AGCTTCATAA AGTGGGAGGG CCTTGGGACT AGCTGAGGAA ACCATTTTTC CATCCTAGGC CTCCAGGCCT GTGATGGGAA GGGCAGCCAT GAAGGTGCCT GACATGCCCT GGAGACGTTT TCCCCATTGT CTTGGTAACT AACATTCAGC TCCGTGTGCA GCACCAACTT ACTTATGCAA ATTTCTGTCA CTGGTTTGAA TTTCTCCCCA GAAAACAGGA TTTTTCTTTT CTATTGCATC ATCATGCTGC AAATTTTCAA ACTTTTATGC TATGCTTCCT GTTGAAGACT TTGCGGCTTA GAAATTTCTT CCCCCAGATA CCCAAAATTA TCTCTCTCAA GTTCAAAGTT CCACAGATAT CTAGGGGACA AAATGTTGCC AGTCTCTTTG CATAGCAAGA GTGACCTTTA CTCCAGTTCC CAACAAGTTT CTCATCTCCA

TATGAGACCA TCTCAGCTTG GACTTAGTTG TCCATGTTAC TATCAACATT TTGGTCAAAG CCATTCAACA AGTCTCTATG AAGTTTCAAA CTTCCCCATG TTTTCCTGTC TTCTAATAGC CCTCCAAATT TTTCCAACCT CTGTCTGTTA CCCAGTTCTA AAGTCACTTC TACATTTTTG GGTATCTTTA CAGCAGTGGC ACTCCCCATG GTACTAATTT ACTGTATTAG TCTGTTCTCA TGCTGCTAAT AAAGACTTAC TCGAGACTGG GTAATTTATA AAGAACAGAG GTTCAACTGG CTCACAGTTC AGCATGGCTG GGAGGCCTCA GGAAACTTAC AAACATGGTG GCAGCAAAGA GAAGTTCCAA GCAAAGAGGG AAAAGCCCCT TATAAAACCA TCAGATCTTG TGAGAATTCA CTATCATGAA AATAGCATGA GGGTAACTGC CCCCATGATT AATTTACCTC CCACAGGGTC CCTCCCATGA CAGGTGGGGA TTATGGGAAC TACAATTCAA GATGAGATTT GGGTGGGGAC ACAGCCATAC

CATGCCAGCT AGAGAGCCTT AAGAAAGTCA CCTAATCTCC ACAAATAAAA GGTTTCCTAT TTGTTCAACA AAAATAATGA CACCCCTTTT ATGGGATTTC TGTGAGGACA AATGATAACT AACATAGCCT TGCATAGTGT CTGGCACAAA ATAGCTACTC AAAAAATAAT AGAAACAACA TTTAAAAAAT GTAGACTTTA TTTTTTAGAG TTTTATGTAC AAAGCAAAAT TGAGCAGAAT GTACAGAGAG TTTCCGTATA GCACTCCCTA CCCCCAAGCA CAGATAGCCT CCCCCAGTAT CAGCATCCCG CACCAGAGTG GTACATTTAT TATAACTGAT GAATCTATAT TGACGTGTCA TTTTCATCCA AAATCCATAG TTTATATTAG GGATGCCTCT TGGTGTTGTA CCTTCTATGG GTTTTGACAA ATGTATAATG ACATGTATTC ACCATTACAG TATCATAAAG AATAGTTTCA CTGTCCTAAA AATCTTTGAT CTTCTTCCTA TTCATCACTC CCTCCCCATT AATCCCTGAC AACTACTGCT

AATTTTCCTG TCTCCATTGT TTTGTCTTTT CCTGAATGTC ATATAGTTTA AATATACAGT ATGTAGGATT TTCAAACTGG TTTATTTCAC TTAGTAATAT GCATTTGATG TTCTTCCATA TCTTTTCAAA GCTTCATAGT TCAATATTTA TAGAATTGAA TAATATTCCA TTGTCTGGAT GTACTACAGT TTATGTATTC ATTCACCTAT CAAAGAACAC CTTGGTTGCT TCCAAGTTTC AACAATCATG AGTAAAGCTG CTATAAACAT CTATGTACAT GTTTTTTTGT GAATTGAACA TTTTCAGCTT TTTTAGCTCC ATTCCTAGGA GTGCAATTGC TGGATTGTAT GATAAGGGTA TGTTTAGTGT TGTAAGAAAC TGCCACGCTC TTCCTAACTG GATGTACTGT TTTGCATTCT CACCAGCAAT GAAAGAGTTC CTGTTGCTCC ACATACTCAC CAGCATTTGG TGTCGTCAAT GTTTTGAGCA ATAGCATTTT GATCTAACTT TTCCTAGGTA TTCTTTTTGA AGGAAATAAT ATGACAGATA

ATAGAGAAAG GATATACGAG GACAGTTCTG TCCTTTATTT ATAGTCCATC ATTTAATGAA GGACTCTGTC CACACTTGGT ATTTTTAACT CTGATCCTGC TCTCCCATGA ACTCTGACAA TCTCCTAAAT CCCTGTTGCT GGCACACATG GTTGTGTATC AGGCCCCCTG TGGTCTGTCT GAAGCATGGC χχ_TTTχχ_τχχ _τχ_ττττττχχ TTTTTTTGAG ACGGAGTCTC GCTCTGTCGC CCAGGCTGGA GTGCAGTGGC GCGATCTCGG CTCACTGCAA GCTCCGCCTC CCGGGTTCAC GCCATTCTCC TGCCTCAGCC TCCCGAGTAG CTGGGACTAC AGGCGCCCGC CACCACGCCT GGCTAATTTT TTGTATTTTT AGTAGAGGCG GGGTTTCACT GTGTTAGCCA GGATGGTCTC GATCTCCTGA CCTTGTGATC CGCCCGCCTC TGCCTCCCAA AGTGCTGGGA TTACAGGCGT GAGCCACCGC GCCCGGCCTT TTTTTTTTTT _TTχχ_TTTTTT XXGAGATGG AGTCTGTCAC TCTGTCACCC

AGGCTGGTGC AGTGATGCAA TCTTGGCTCA CTACAACCTC CATCTTTCAG GTTCAAGTGA TTCTGCCACC TCAGCCTCCC AAGTACCTGG GATTACAGGT GCCCGCCACC ACACCCAGCT ATTTTTTTGT ATTTTTAGTA GAGACGTAGT TTCACCATGT TGGCCAGGCT GGTCTCATTC CTGACCTTGA GTGATCCACC TGCCTTGGCC TCCCAAAGTG CTGGGATTAC AGGCATGGGT CATCACATGT GGCCTGAAGC ATGACTGTTG CTTTAATCAT ATGAAATACT GCTCTGTATT GTTATCTATT TGAAATGCCA CACCTCCTGA GCTAAATTGC AAGCTTTTAT GGAGCACAAA CCATATTTAT ATATATTAGC ATGATACCAT GACACATATC AAAAGCTGTT ATATATTGTT ACGTGAATTG ATTCTTTCTC AGTTAAGAGG ACCTCTGTAG TAGCACTTTC ATACCGTTAA TTTTTCATTT TGTGCCCAGC CCCTACTCTG TGAAAAATGA AATGAATCCT GTTATCATTT CCCTCCCAGG

CCTTTTCTCC TTGTGGACAA TGTGTGOCTC AAGAGAAAAT TCAGTCAGTA AATTTGTTCA GTGCACAAAC TCTTTATCAC CTCTCACTGT TCTCAAGTGA GATAGAACAG AACATCCATC CAGTGTCTTA CAAATTGTCT GGTATATAGT AGGCACTCAA TAAATGTTTT TTGAATAAAT GCATACATGA ATCCTATTCC TATATATAGT ATGGTAGACA GATCATTGAT ACCCAAAGAT GCCCAAATGC TGATCCCCAG AACTTGTGAA TATGTTACAT TTCATGTCAA AAGGGACTTT GCTAATGTGA TTAAGGATTC AGACCCTTGG ATTGTAAGAT TATCCCGGAT TAACCAGGGC CAATCTAATC ACATGAGACC TTAAAAAAGC AGAAAACATT TCCCAGCTGG GTTAGAGAGA GATGAGACAG AGTAAAAAGG AAAGAGATTC AGGGCATGAA AATGACTCTA CCCACTGTTG CTGGCTTTGA AGATAGAGGA ACTAGGCCAC AAAACAAGGA GTATGAGTGG CCTTAAGAAA

TAGGAAAAAG CCCTCATCTG ACAGCCAGCT AGAAAGCAGT CCTCTGACCA CAAGAAATTG GATTCTGCCA ACCACTCAAA TGAGCAAGGA AATGGATTCT CCCCTAGAAC CTCCAGAAAG GAACACAGCT CTGTAATGCC TTGATTTTAG CCAGGTGAGA CCTGTTTCAG ACTTTTGACC TATGGAAATA TAAGATAATA AAGTTTTATT GTATGCTGCT AAATTTGCGG TAGTTTATTA CTGAAGCAAT GGAAAGCCAA TACAGACAGA ATATACAGAG AGAAAGAGAA TGAGTTCTTT CCTGATAATT TGTAAATATT TGGGTCTTCA CTGGACAAGC TTCACAGAGG ATTCACTGGT TCCCTAGCAA ACCAGCATGT CCAGTCCTGC AGCCTCCCTT TCTTAGGCCC AGCATATGTC AGCTGTGTGC ATAGAAAAAT CAAAGCAGGA CCCTGAGTAG TTGGAAAGAA AAGATGGTTG GAAATGGGTT GCACTTCAAG TGAGGAAACA AGAGGTAGGA GACCGGCATC TCTTTCTCAT ATGTCCCAGG CTGACTCTTG TGAGTTGTTT TCCCTTGGAG GCTATCGATG ACAGTCACAG TAACCTGATG GAACCTGGAT CATGATGAAA GAAGTAAGTG TCAATGGCTC CGACTTCCAA GGACTCTGAT GTCCCACAGC ACTAGCTAAA CAAAGCCAGT TGGAAATGAG CTTAAATGGG GAATTTCCTG AATATATTCC CTATTGTTAG GAAGCCAGGT TGGCTTCCTT GCCTACAATT ATGCCAAGCA GTCACACTAT AGAGTCCCTA GGGACATGAT ATTAAGTGAT TCTTTTAACA CAAACAACTT AATAATCATT TATACTAATA GCAAAACGGC CAACGGCTGA TATTCCACTT GAAGTAGAAT TGGCTATCCA ACTGGAAGAG AAGACAGGAA GACGTGATCT CCAGGGAGCC ACTAAAAGGA

TTGGCACCTG CCTCTGGATT CCCCTTTTCC TTATATTACC TCTCAGCACT GGCAGGCCTT TATTTCAGGA TACAGTTTCA CAAGTATTAT GTCACGTCTC TGAGAATTAT GTTGGTAGAT ATTTGCTCCT CTGGCCAGAA AGACCTAGTT TGGAGTCTGG AGTCATGAAG GTGACATACA TGTAGCTAGT GACATAAGTG TAGCTAGTAA AAATAGTGAG TAATGGCCCT GAAATTCTAT TGAATGCCCA AAGTGCTGAC CAGGAACAAG CATGCTCTAG CTTATCTCAC AAGGAACTTG ACAATTTTCT TCAAAAATCC TAGTAGCTAA GATTTCTTAG TAACAAAGCC ACTAAGGCAC AATTATGATT AACTTGACCC TTAGGTGACT TTTAAGGACT ATTCTATAAA ATATTACAAC TAATAGTGGA TCCAAGCCAG CACACTCTGC TATATAAGAT TAATTGACAG TGTCCACACT GGTAAAATAA GTTGTTTCAT AAATACATTA GAATTCATTT GCACTTTCTA CACAGCCCCA AGTCCAGAAC

TTTCCCCAGA ATAGGTCTAT GTTTTGCAAT CTGCTACTCC ATACAGAGAT TTGAGTTCAC TTGGCAATTT AGTGCTGCTT ATATGTGACC AGTTAGTCTG TTTTACTTAT CTATGCCTTA AACATTACTA TACTTACTAA CTCCAAGATG CCTGGTCTCA ACTTGACAAA AATACCCCAA GTTGGGAAAT CCTTATGTGA ATATGTAGAT AGTCACAATT GCTGGTTGAT GATGATCTGT CTTTTCCTGT ATTTGAGAAA ATGGAGATAA AATGGACCAA TCCAAATAAT GGATTAAACA TGGGAATAGG TGAGAGAGAG AGAGGAATAC ATGGTGGCTC TCAGTGTCTG GCTTAGGCAG TAAACACTTT CGTTAATAAA GACGGAAAAT AAAAAAGGAA TAATTGGTGT CTAGGGGAAA ATAATGAGCT CAAGTTTTAA CACTCTGAGT TCCCGGATGT GAGACATCCA GGCGCATTTA TCCAAGAGGC AGTTGGAAGC AACGTTCCGG AGCTTAGGAG AGAGGCATGA CCAAAAGCTG GTGGGACTGT

GAAAAGGTAT GGCCATTCTG GAAAACTGTT TGGCAGTTTC TTAGAAAATT AAACATGTAC TAACAACCCA GCAATTGTAC TCTTGAGCAT TTGTCCCAGA TAAATGAAAA AAAAAAAAAG CATTTTTTTT ACACAAAAAC ATATACATGA AAGTTCATAG AAGTGTTATT CATAAAAAAC TGGAAAAAAC TGAGATGTCT TTATTGAGTG AATGCTTAGG CAAACGGTGG TCTATCCATA CAATGGAATT ATGCTTAGCA ATAAAGAGAA AAGAACTATT GATACATGCA ATAACACAGA TGAATCTCAA AGGAATTAAT GCTGAGTGGG AAAAAAAGCA CATCTCAAAA TGGTATATAC TGTACTATTT TATTTACTTA ACATTTTAAA AATAGCAAAA TCATAGAGAT GGAGAACAGA TTAATGGGTA CTGTGTTTTG GGATGGGGAG TGAGAAAAGG GTAAGGTGTA AATATAAAGG GGTAGCACAA AAGAGCCTTG TGGTTGAAGG ATTCTATGTC TTGGTTGTAG TCGTGATTGC AGGAATCTAC

ATGTGATAAA ATTGTATGGG TCTACATACG CATACACACA AGAGCATATA AAACTGGTGA CATGTGAAGA AGCTCCGCAC ATTGTGCCAA CATCAGTATC CTAGTTTCAA TATCAGACTA CAGTTATACA AAACATTGTC ATTGAGGGAA ACTGGGTAAA GGGAACACAG GACATTTGGC ATATATTTTT GCAATTTCCT GTGAATCCGT AATTATTTAA AAATAACAGA TATACTACAT ATCAAAAATT TAATGTCATA AAGTTGATGA GTTTACCTAG TGGATAGCTT TGTTAATATC TGCTATAAGA CTACTGAAAA TGACAGTTAT GCAAGTATAA GCTCAGAGAA CTTTCCTCCC CCTTCGTAAA TGAAATGAGC AAAAGAAATG AAACAGGAAA GGCAAGCAGT ACTGAAAACA GGGAAGGGCT CTTCCCCATA TAACTATATC TGCGACTTCA ACAGCTATTC ATCCAGAAAC ACAGCCTCTT GCGCTAAGAG GAAACTTTGG ATAACAATAT GTTTTCACTC TCCAAGAGAG AAAATGGATA

GATTAATTTT TAAGAAAAAA AAAAAAACCT CACCAATTTC ATGCTGTGGC TTGCACCTTT AATCCCAGCT ACCTACAAGG CTGAGGTGAG AGGCTTACTT GAGCCCAGGA GTTCAAGGCT GCAATGAGCT ATGATTGATT GTGCTATCGC ACTCCAACCT GGAGTACTAA GCTAAGAGCT AAGAACACAG CTGAGAGCGG AGAAGAAACA AACAAATCTG ACCAATAACC CCCACTCCCC TCATTTTACT GGAGTGAGCT GAGACTGCTG GCAAACATGG CCTTTGACCT AGCCTGAACT GTAGCAAAAG TCATCAGATA TTTTTCCACC AATCAACAGA CAGAAGTGGG GAGAAAACAA TCGTAGTTCA TAACTACAAC AAGCAGATAA ACGAAGGCCA TGGTGAGGGA TGGAAGACAT TGTGATATAT CAAAGGCAGG CTCATTTAAA ACTCAACCCA AATTCCAAAC AAAATATATA ATTGAATATG TATTAATGCC AAAGGAGCTT GAGTGAGCTT TAGCACAAAC CCCGCCCTCC

AGCCCCCACC CAAAAAAATC ACTCTGTTCT CTCCCCATTC TTTGATAGGC ATACTTGCTG TTTTCTCACA GCCAAGGTAC AGAGGGGACT TAGAGGAACT AGAACTCTAA TACACTGCTA GCAGGAATGT AAAATGAAGC ATCTACTTCA GAAAACCATT TTATCAGTTT CTAGAAAGTT AAACATAGAC CCACCATGCA GCCCAGCCAC TCTACTCCTA AGTATTTACA CAAGAGAAAT GAAAACGTGT CCCCACACAG TTGTATTTAA AGGTGATGGT TAGCCTTGTG TGTCAACTTG GCTAGGCTAT AATACCCAGT TACTGAATCA AATAGTAATC TAGGTGCATC TGTGAAGGTA TTTTGTAGAT GTGGTTAACA GCTACAATCT GTTGACTTCA AGTAAAGGAG ATTGCTCTTG ATAGTATGGG TGGGCTTCAT CCAATCAATT GAAGGCCTTA AGAGCAAAAA GTAAGGTTTC CCGGAGAGAA AGAAATTCTG CCTCAAGACT GCAGCCTGAA CTCCTGCCTG AGTTTCCAGT CAGCCAGCCA

GCCTAAAGAT TTGCTAGGCA TTATAATCAC ATCAGCTAAT TTCTTAAAAT AAACCTCTTT ATATATATTG ATACAATGAA TGGTTATAGC AGCCTTATTT GTAATAGCCA CAAACTGGAA ACAACCTAAA TGTCCTTCAA TAAGTGAATA CATAAACAAA TTGTGGTATA TCCACAATTT TTACGCAGCA GTAAAAAGGA ATAAATGGTT GAATAAGGAA TAAACACATA ACAAGGATGA ACCTTAAAAC CGTAAGGCTG AATGGAAAAA GTCAGACAAA ACTAATACAT ACTGAATAAT TCCATTTATA TTGAAGTTCT AGAAAATGAG GACTAACCTA TAGTAACAAA AAGCAGAAAA ATTTTGCCCA CTGGTGATGG AGGGGGCGCA GGTATTGTAG AGTATCTGAG AAAGGACAAC TGGATAAAAG GGGGCACAAG AAAACTTTTG AGGGTGATTG ATATGTTCAT TATCTTGTGG CATGGTTTCA TAGGTGCATA CATATGTCAA AACATCAAGT TATACACTTT TAAAATGTTC

AGTTTACTGT ATATCTATTA TACTTCAGTA GAGAGGAAGG AAGAAAGTGG GCAGGGTGGG GGAGAGGAAA GGAAACGAGG GAGGAAAGGC CCTAATAGGA AGGATTTTGG AGTTTAGATT TTAAAATGAT AAAGGATGTT TGACACTCTA GGCATATGAC GAATATAGGA TTATGAGTCC ACAAAAACCA CCAGGAAGTC ATGTATGTTT ATACTTTTAA GTGAAGGATC AGTGGATTAT CAACTCCCTA ATGCTTTGCC TCTCTATGAC TGGCTGCTGT CCTTCTCATC CCAATACTCC TTCCAAAGCC CCTTGCTTAA ATGTAAGCCT TCTTTCCTCC TTTCAACACA TCCTGCATTC CGTGACAAAA TAAGTTTTCC TTAAACAGAA TGTACAGCAT ATTATTTGTA CAATTAAAAA TTTTTGGCCA GGTGTGATGA CTCATGCCTG TAATCCCAGC AATTTGGGAG GCCGAGATGT GTGGATTACC TGAGGTCAGG AGTTCGAGAC CAGCCTGGCC AACATGGTGA AACCCTGTCT

CTACTAAAAA TACAAAAATT AGCTGAGTGT AGTGTGGCAG GTACCTGTAA TCCCAGCTAC TCAGGAAGCT GAGGCAGGAG AATCGCTTGA ACCTGGGAGG TGGAGGTTGC TGTGAGCAGA GATCAGACTA TTGCATTCTA GGCTAGGAGA CAGAGTGAGA CTCGGTCCCC AAAAAAAAAC ACATTTTTTT TTAATGTTTC CTCCTTGCCT GTAGGAAAAA GGCTCTGACT CCTTAGCCTG GGCATCAGAG CTCTATCTAA ATGGACTTTA ACCTGATTTT GTGGCACTAA TTCCATTGCA GTACTTGTCC GCTCACTGGC CTGTGCCTCT CTGCCACTAT TTTTGGAATA ATGTCCTCTC TCCATCTTGT TTACTCAACT ATATCCAACC TCTAAGGCTG TGCTCCTACA AAGCCTCCCC TGGCTACTTC AGCCCACAGA GATATTTAAC TGCTCTGCAG TTCAGGACAT TCTTCTGACT CTTTAAATCA CATTTACTTA TATATGATCT TGTGATATTT TTTGTTGACG TGTTTACTTT AATTTTCTTC

CATAACCTAT TCATTCAACA AACTCAACAA TTATTTATTA AATGCCAAGT TAGAAAAATA TTATTGATTT TATATAGATT ATAGATATGT TTGAAATTTT ATTTGGCAAT CTGCAAGTAG AAAAATAATT ATAATGTGGT ATATCTGTGA TAGAAGTATT AGTGCAGAGA CCATGGGGAA CATAATCCAG CCTGGAAGTT CAGGAGAGAT ACGTGGAAGA AAGGACGTCA GAGCCTTTTT CCTACAGGCA TGGAAGAAAC ATTAAAAAAA ATTTTTTTTT TTGAGATGGA GTCTCACTCT GTCTCCCAGC CTAGACTGTG GTGGTGCGAT CTCTGCTCAC TGCAACCTCT GTCTCCCGGG TTCAAGTGAT TCTCCTGCCT CAGCTTCCCA AGTAGCTGGG ATTACAGGTA CCTGCCACAC ATGGATGATA AATATGATCA TATTTTCTTG TTCTTTTCCT CCTCAGTTGT CTTCCCTGAA GAAAGGAATG CCTTTTATAG ATGACAAACT CCCATTCTCA AGAACAAGGA TTTTTGACCA ATTTAATTTA

ATCAGATGTC TGGCTTTGAC CTAGAAACAC AGTCACGAAA CTTGGTGATT AGAGACCAAT TCCCAAACAT GAGCATTTCT TAGGAAACAC AGTAAAGATC TGAGAGACCC AAGAGCAGAA GGGCGAGAAA CCAAAAGCCA TCAGTTTGCA TAGGAAACAC CTTGTTTAGC CTAATCTTTT TATTTTTATT ACTCTATTAG TCACTACAAC TATTTTCTGA TTGCTATGGT GATAGATGGT TTAAAACAAG CCTTCATTAA GAATTGTCAC ACCATGGTCT CAGTCAAAAA CACCAACATT TTTATTGGTA TTGACAATTA TGGGAATATC CAATTCCAAG AAGACAAGGA GACCTCTGAA CTTTCTAAAT GAAGACTCCA ATCTTCCTGA TCTGATGGGA AGCAGCTTGG CAAGATTACC AACCACCACC ACAGAGAGTG GACTCTAAGC TAAGACTTAA AAGATAAGTA GAAATTATCC AGGTAAAGAT GTGTACAGAG AAGGAAGTAC ATCCAGGGGA AAAGAACAAT ACGTGCAAAA

GTACGGAAAT GGTAAAAAGT AATACTACAT AGTCAAAGCC AAGCAGAGTT CAGAAGGGAT CTGGTGGTGA AAAATACGGC TAGAGAAAGC AGCAAGGATT GGCTTCTAAA ACCTATGTAG TATCTTGGAC CTTACCCTAA ATGTAATGAG AAGCTTCTAA AGAATCTTTC ATTTATTCAT TCATTGAACA AATATTTTGA GGCTTTCTGT GAAGAACATC ATTCTAAGTA GTAAAGATAC AGCAGTGAAT AGGACACATA AAATCCTAGA TCTCACAGAA TTGACATTCC AGAGAGGGAA AGGTAGACAA TAAATAGATA AACAAATCAT TTAACAAGAT GATTTCAGAC AATGGTACGT ACTGTGAAAA AAATGAAACA AGGTAATGGA CAGCGAAAAG GCAGTGGAAG GAAGCCTGCT TACCTTTGCA TGGTTAGAAA AGATCTCTCT AAGAAAGAGA CCACATGTGA GCTGCGACCT GAAGGATACC GAGAAGCTAG GTGTGCAAAG ATGTGGGGAC AGAACTTTTG

GACTGAATAG CAAATACAAA TGCCCTTGGG TGCAAGCTTT GCCTGTTCAA GGACCAAAAA GAAGGCCAGT GTGCCTGCAG CATACTAAGC ACAGAGGAAA ACACTGTTAT ATGCTGAGAT TGGAATTATA AGTAGAGCCA GATAATATAG TCTCTTATAG GTCATAATAA GGCAACCAGA TTTTATTCCA AGAGGATTTA AAAATCACTG GAGGTTTTGC ACTAGGGTGA GAGGTGTGAT TTGTATTTTT AAAAGATAAT TCTGGAGAAT TAACTATAAT GAGGTAGGAG TAAACTAAGT TAGGGGCTAT TTCAGTGGCT CAGACAAGAG ATAATGGTAG CTTAGACTAG GATAGTAGTC GTAGAAATAA ATAAAAGTGG CACTCTACTT TGGGGGTAGA GTCTATAATA GGTTTGGTTT ATGGATCATA TATGAGAGTA AAAAAAAGAA AATAAATTAA TAATGGTTCC TAGGTTTGTA CCTGAGCAAC TGAATAAATG GGTGCTGTGA ATTGAGATAA AGGAGATTGA GAATCACAGG CTTTGTTTTG

CAAATTAATT TTGAGAGGCT TATTAGACAT CCCAGTGGAG ATTTCAGGTG AGTGGAGCCC ATTGAAAGGT AAGGGACAGG GTCAGGTGTG GTAGGTCAGG CCTGTGATCC CAGGACTTTG GAAGGCCAAG GCAGACAGAT CAGTTGAGCT CAGGAGTTTG AGACCAGCCT GGGCAACATG GGAAAACCCT GTCTCTACAA AATATGCAAA ATATTACCTG GGCATGGTGG CATATGACTG TGGTCCAAGC CACTTGGGGG GCTGAGATGG GAGGATCACT TGAGTACAGG AGGCGGAGGT TGCAGTGAGC CAAGATCTCG CCACTGCAAA CCAGCTTAGG TGACAGAGTG AGAACCTGTC TCAATAAATA AATAAGAAAC GTAAGGGAAA AGGAAATTAA TCTGATCATT GGCAAATGCA TAGTATTTAA AGCCAGGGGA GTAGATGAGA TACTCAAAGT AGGTGAAGAT AAGGAGGCAA TGAAGGCCTA GGACTCTGGT GTACATTTAG ATGGTTATAA GAGGAATAGA

AACTGGCAAA ATAAGTAACA CTGAGCACCC AATGAGGTGG AGAGGAAAGC CAGGAGATGA AGCATCATAG AAGGCAAGAG AAGAAGGGTG TCAAAGAGGC GAGGCAGTCA TCAACTTCTG GGCAGTCAAA TAATATAAGG ACAGAAAAGT GACCATTGGA TTTGGAAATA TGATGAGCAC TTTGAGTGGA GTGTTGAGAC AGAAGACCAA TTAGAGTAGA TTGAGGAGAT AACGAGAAAT GAGAAAATGT AACCTGCAAG CACAGACAAT TCTTGAGAGA CTTTTCTGTG AAAGGAAACA GACACAGAGT CTTAGCATGT CTTGTCTTTC TATGGGAAAT GTAAATAGTT TGAGATCAGG GATAGTATTT TATTCTGCTT TTTGTACCTC TACATTACCT AGCATAGAGC TAGCTAATGT GCACTTAAGT ATGTTCTCAA TTCTTATCGC CTGAATGACT GGATGGGTGA AAGAATGGAT GGATGGATGG ATGGATGGAT GGAAGGATGG ATGGATGGAT GGAAGACTTC TGATTTGCCA

AGAAGAGGAT ACTGGTAGCA GAAATAAAAA CAGCACTGGA GAAAGAAGAG TTTAGATTTT TATTCTTTGG TGTCAGTTAG ACAGGAAAGT AAGACATTAG AAGAGTCCTT AGATAATTTA TGTAATTGTT CACTTAGGAT TTTTAAATGT GATCACTGAT ATTGGACATG TTCCTAGTGA AGCATTTTTG GTGTTTCACT GGTTGAAGTT AATAACTGTA AAATTATTTC CCGTTCAGGA CAGAAAAACA GAAAACTTGA AGCTCCTATT AGAAAGTTCA AGATTCTCTG GGGTTCTTAG GATTTACTGT TCCCAAAACT CTGTCAAGAA CAAGAAAATG ACCTGTATAC TTAACTGGTC TAGGCAACAG TGGAAAGACA ATTCTCAGAG AAGATTTGTT TTAAGAAGAC ACTTTCCATA GGAATCAAAC AATAGCTTTC AGTGACTAAC ATGGTAAGAC ACAGGGTGTT AGCTCTTTCC TTCCAACCTC ATGGCTGTTG TACCTTACCT TTCGACCCCG TGTTCCTGAA ATTGTTAAAT TCATAAACTT

ACCAAGGACT AACCAGCCTC TGGGGAATTG CTGTATACTT AGCAAACTTA CAATGGACAT ATTTATAAGC CATAATGATA ACTGACTAAT AGGAAATACC CTCAACTGAA AATGAGAGAT CATCATTTGC AAATGAGTTC CCTTGCCCAG GCAACTACTG GGGAAAATGT CATGCAAGCA AAATTAATCT TTGAAATCCT CCTTTTCCAT TTTTTGTGTC TTCCTTTTCC ATAGGCACCA GAAATATCAT GGTGCCTGGA TCTCATCTCT ACAGAAAAAA AAAGTGATTT GATAAACTGA TTTATATTGT GTCCAAATGT GATTGTATTT TCAAAGATAA CCTAAGGGGA GAATGCTGTC TGGCCCAACA GCAGGCTCTC GACTTCATTT CAGACACTGT GGCCAATGGC TGGGAAACAG GTATGAACAG TAGGTTTCTG AGTCCCCTGG AATTATTCCA TTTATGTAGC CACCTCCATG ACAGGAAGCC TCCCTACTCT TACTTCCCAG TTTGTTCATT CATGGCACCA GGTTGCAGAT TAAAATTTGC

TCAGTGACCT TTTATCTAAT AATGTGTTAC CTTCTTCTCT TAAAAAGTAC AAGGGACAAA TGCTCATGGT ATACTTTTAG GAGATTGTGG CTCTCTATTA ACAGTATTTA TTCAACAAAC ATTTATTGAG CATTTATATG TGCATCATGC TAGGGACTGG AACCTAGTAA GTGTAGCACA TATTATTTCA TTTAATCCTC ACAACAAACC CATGAGGTTG GTTTTATGAT CCCAATTTTT CAGAAGAAGA AACTGATATT CAGAACCAGT TAACTAACTG GTTCAAGGTC ATGCAATTTC TAAGATACAG AACCAAGAGT CAAAGACATG ATTTTAAACC AAAGCTTTTT CTGCTACTCC ACATTGCTTC CCTAGGTGAG ATCTGAGGCA TTCCGCGAAA AGAGAAGGGT CATAAAGCCA AGGGAAGACA AGCTTAGGAA AAAAAAGGGA AATGTCCTAA ATAAACAGCT TTCCTATTTA CCAGAAACCA CTAGTTTAAA AATATAATGG GAAAAATCCT ATTCACTTTA ACAATGTTAA AAAAAAAAAA

GATAGAAGAA ACATAGGGAT AAACTTAACA CATTTGTAGG ATATGTAAAG AAACTAAAAG ATGTTAATAA TGGCCTAAAG AAAAAAAAAC TTACATGTAT GGGGAGATAG ACCATCTTAC TGGATTCTAA TATTTAATAG TCTAGGTGTT CCATTTCTCA CCAAATTAAT GTATACATTT AATACAATGT CAAACGAAAT ATCTTAGGAA TTGCTTACAA ATTGTCAGAT AATTACAAAG TTTACCTGGG AAATATAAGC ATATATGAAG AGTGAATGGG ACCCCACCAC TCCCCCCAAA ACAAAAAAGG TCTGAAAAGG ACAGAAATCA AGGAGAGTCT TGCCTGCCAG ATACAAAATT CTATTATAAA GGTGTATTGA TGAAAACAAT TTAATACTAG TGTAGCAATA GGCAGCAAAG CAATGAAACA GCATAAAAAG ACCAGAACTA TACCTAATTA TGATGAAGAT TTAAGGTATG ATAAACATGA CATAATTCAA ATCAGCAGAA ATTGGCATAG ATAGGGTTAA GACAAATAGC TAATCATTAG AGGGGAGGAA GGAAAGGAGG GAGGATAAAA TTAGGTTCCT GCCTTCATCT TACATTAAAA TAAATTCCAG ATGTATTACA TTTAAATTTT TTTAAAAAAA GAAACCACAA AATACTTGAA GAAAATATAA GTTGTTATAT AGTCTTTTGA TGGGAATTTT TTTTTTTTTC AGAGACAGGG TCTTGCTCTG TCACCTAGCC TAGAGTGCAA TGGCATGATC ATGGCTCACT GCAGCCTTGA ACTCCTGGGC TCAAGTGATC CTCCCAGCTC AGCCCCCCAG GTAGCAGGAA CTACAGGCAT GCGACACCCC ATCCAACTTA TTTTTTATTT TTTGTAGAGA CAGGGGTCTT GCTTTGTTTC CCAGGCTTAT CTCGAACTTC TGCCTTCAAG CACCTCAGCC TCCCAAAGAG CTGGGCTGAT GGGACATTTT

TTAACATAGT GCCACATTAC CATAAATGAA AAGCTTGTAA AATACTAATT TTTAAAACTA ATATATATCA GAAATTTTTA TAAACAAAGT TAAAAAGCAA ACACAAAAAA TTTGTAGCAC TTATGACAAA TATATGTATA TATATGAATA CAAAAAGAGC CTTTACAAAA CAGTAAGAAA ACAATGAATA CTCCCAATGG AGTATTCAAA ACTAAACTGC TAAAAGCAAT TCAAAACAAA AAACATAAAC TATGCATATA TGTATGTGAA AAAGTTTAAC CTTATCAAAG AAGTAAACTC TCAAAGAAAT AAACATCAAA TAAGGAAATA GCCTTTTCCC ACAAATAACC AAAATCTGTA AGAATACTGA GCTGCGAATG TTTCAGAAAA AAAAAAAAAT CATACACCTA GTTCGGCATG TAATTAATAT AGATCAGAAC ACTTTAAAAA TATTTATAGG CCAGGCACGG TGGCTCATGC CTATAATCCC AGCACTTTGG GAGGCCAAGG CGGGTGGATC ACCTGAAGTC AGGAGTTTGA GACCATCCTG

ACCAACATGG TGAAACCCTG TCTCTACTAA AAATACAAAA ACTAGCCAGG CATGTTGGCG TATGCTGGTA ATCCTGGCTA CTCGGGAGGC TGAGGCAGGA GAATTGCTTG AACCCAGGAG GTGGAGGTTG CAGTGAGCTG ACATTGTGCC ACTGTACTCC AGCCTGGGCA ACAAGAGCAA AACTCTGTCT CAAAAAATAA TAATAAATAA AAATAAAATA TTTATATACT CTGACCCATC AATTTGTCCA GCATAATTAG GCATGTGTAC AAGGGTTTAC ACACAAGAAT GCCTATTGCA ATATTGCTTT TAATGCTAAA AAAAATTGGG GAAAATGCTT TAAAAATATA GATTAAGACT GTACATTGTG GTACAGTCAT ATAATCAATA GTATACAGCT ATTATTTATT TTCAGCCACT GTCCAAAATA TAGCCTGGCC TAACAACATT CTGTTAGGAT ACGCAAGCAC CGTGAGGAGA TCAGCTATAA AGTATCAGTG TTTCACACCA CTGCTCCTTT GCTAATAACC TTCAATGGCT TTTAAAGAAG

TAAAAAACAA AGGCAAAATT CCTTAGTCAG CCCTTAAGAC TCTCTGTTAC TTAGCTCAAA CTACCCTTTT CAACAACACT GCCCTAACCA GGATGAGTTT TTTGCCCCCC TGGAGTACAT TCAGCCTTTC CTTATCAAAC CTTCCTTTAA ATAAGTATCT TCTCCAGGAC CACTTCACTT TCTTCCCCAA TTTAGCATTT TCTATATCTC CAGGCCTACC TCTATAAAGC CTGTCCTAAC CACTCAAACC CTAGCTTTTT CTCTGAACTG CTAGAAATAT TTTTCTCTCA TTGGCCATTT AGGTAAAAAG GTTTTTACTG TTTATTACCT ACTCAATAAA AATTTTCTTT TTTTGAGACA AGGTCTTACT CTGTCGCCTA GAATGGGGGG AAGTGGTGTG ATCACAACTC ACTGCAGCTT CTACCTCCCA GCTCAACAGT CCTCCCACCT CAGCCTAGTG AGTAGCTGTG ACTACAGGCA TGTGCCACCA TACCCCACTA CTTTTCATTT TTTATTTTTT GTGAGATGGA ATCTCACTAT GTTACCCAGG

CTGGTCTGCT GATCTCAATT GATCCTCCCA CTGTGGCCTC CCAAAATGCT GGGATTACAG GCATGAGCCA CAATATCTGG CCCCAGTAAG CTTTTAAGGC CATTAACATG AGGAACAGTG TTCTTTACAC TATTTTATCA OCTAGGGCTT TGCATGGAGT AGGAGTTTAG TAAATGCGGT TGATGGGTTA ATCAATGTGT GAAAATATTC AGAGCCACCA AAAACAGATA TTATGTCTAT TCTCATCAAC AATCAAAATT GAGTAAACAG CCATTTTCTA ATACAGGAAA CCACAAAACA TTGAATGGTG ACATTAAAAA ATTCCCCCAG CAGGAGCCAA CCAATTTTTT CATCCTGATC CAAGTTAGCA AACTGCAAAA GATAGGAAGC ACTAATGAGT GGAAATTTGA GTAGAAGCAT TTCTTATGAA GGCTGTCTTG ACTGGATCAC ATTTTTATTG CTGTTGGAGG TGCCAAATGT GTGTGTTTAT GCTAATCCTC CACCTCAGGC AACACACAGT CAAGGATCCT ACCAAGTGTT ACCGTCAAGT

GTCTGTTGGC AGCTCAAGGC CCCAGCGTTG TTCCCTTGCA CTAGGGAAAA GACATATTCC AGGTACAAGT ACTCCCACTT TGATGCTACA GAGGAGTTGC TGAACTTTGT GTCATTAATC TCTCTTCGTT AGATCCCAAC CCTGTTTAAA TCCCACTATC TGCCTACTCT GGGTCTTCAC CAATTTACTA GATCATAGTT GGAGAAAATC TACAAAGCCT TGCTCCCTTT AGATTTAAAC AGGTCTCCGT TTAAATTTAG AATTGCTAAC TTCAAGCGGG CCCTTATGCG ACAGTATGCC TGTCAGTCAT ACTACATTTC CTCAATTCCA TTCATGTGAC TGCTCCATAC CCTTCCCTCT CTCTTCATAC TACTATTATC TCTTCCCCCC TCCCTCATTT TTAACTGATG ATCTTGTTTC CTATTTCTCT GAGAAAATAG AAGCCATCAA AAGAGAGTTT CCACAAACTC CTACTGCCTT ATCTAGCCCT GTACCATATA CTTTGCATTT CCTCTCATTA CCATGGATGT ACTGCCTATC TGTGCTTCTA

TCTAAGGCTA ACCCTTCCAC TTCAGTTTTG AATATTATCA GCTCTTACCA ACTCAAGGCC ATTGCTCTAG CAATTCTCTC ATTCTCTCTC ATTTTCTTCC ATCAAGTTTT CCTTTTCTTC AATTAACAGA GTAGCTCCTA AAGGGAAAAA AAAGTCTTCT TTTTCAATGC TCATCATCAC TGGCCATCAG AGAAATGCAA ATCAAAACCA CAATGAGATA TCATCTCACA CCAGTTAGAA TGGCAATCAT TAAAAAGTCA GGAAACAACA GGTGCTGGAG AGGATGTGGA GAAATAGGAA CACTTTTACA CTGTTGGTGG GACTGTAAAC TAGTTCAACC ATTGTGGAAG ACAGTGTGGC GATTCCTCAG GGATCTAGAA TTAGAAATAC CATTTGACCC AGCCATCCCA TTACTGGGTA TATACCCAAA GGATTATAAA CAATGCTGCT ATAAAGACAC ATGCACACGT ATGTTTATTG TGGCACTACT CACAATAGCA AAGACTTGGA ACCAACCCAA ACGTCCAACA ATGATAGACT GGATTAAGAA

AATGTGGCAC ATATACACCA TGGAATACTA TGCAGCCATA AAAAATGATG AGTTCATGTC CTTTGTAGGG ACATGGAGGA AGCTGGAAAC CATCACTCTC AGCAAACTAT CACAAGGACA AAAAACCAAA CACTGCATGT TCTCACTCAT AGGTGGGAAT TGAACAATGA GAACACTTGG ACACAGGAAG GGGAACATCA CCCACTGGGG CCTGTTGTGG GATGAGGGGA GTGGGGAGGG ATAGCATTAG GAGATATACC TAATGTTAAA TGATGAGTTA ATGGGTGCAG CACACCAACA TAGCACATGT ATACATATGT AACAAACCTG CACGTTGTGC ACATGTACCC TAAAACTTAA AGTATAATAA AAAAATATAT ATATATATAT AAAACAACTA AAAATAAATC TTCTTTTTCT GCAGGATCAG TCCATCACCA CACACACAGG CTGTGTTTTA TGTTGTTCCC CAGCTTAAGA GATCGTTCTC CAGATCCCAC TGCTCCTTCC AGTTGTCACC TCAGTTCTCC ACTTCTTTTT GCTGATAAAC

TACTCTAACT AGTTACATAT GATTTCTGTC CCCAGGTCCC CTCCCTCAGT TGTTTTGAAC ATAATCATTT ATATCATTTA TCATTTTCAC TCTAATTGCA CAACCAAAAA CTCCCTTTTT TTTTAGATGG AGTCTCACTC TGTCACCTAG GCTGGAGTGC AGTGGCATGA TCTCGGCTCA CTCCAACCTC CGCCTCACGG GTTCAAGTGA TCCCCCTGCC TTAGCCTCCT GAATAGCTGG GATTATACAC ATGCACCACC ACACCTGGCT AATTGCTTTG TTTTTGTTTG TGTGTGTGTG TGTTTTTTTT TTTTTTTGGA CAGAGTCTCA CTCTGTTGCC CAGGCTAGAC TGCAGTGGCA TGATCTCAGC TCACTGCAAC CTCCACCTCC TGGGTTCAAG CGATTCTCCT GCCTCAGCCT CCCGAGTAGC TGGGACTACA GGCATGCACC ACCATGCCAG GCTAATTTTT TTGTATTTTC AGTAGAGACC AGGTTTCACC ATGTTGGTCA GGCTGGTCTT GAACTCCTGA CCTCAAATGA TCTGCGCACC

TGGACCTCCC AAAGTGCTGG GATTACAGAC TTGAGCTACT GCGCCGGGCT ATTTTGTGTT TTTAGTAAAG ACGGGGTTTC ACCATGTTGT CCAGGCTGGT CTCAAACTCC TGACCTCAAG TGATCCGCTC GCCTCAGGCC CTCAAAGTGC TGGGATTACA GGAGTGAGCC ACCATGCCTG GCCATAAAAC TGCCCTTTGT TAATATGACT GTTGGCCTGC ACATTGTCAA ATCCAGTGGC ATTCATCTTA CTCGGCCAAC CTACGGCATT TGACACTGTC TGTCTTTCCT TCTGTTCCTC TATCTGTTTC CAGTATACTG GCCTGGCTTT CTTTTTACCT CTTTTATATG CTCTTCCAGT CTCAGGCTCC TTTGGGGATT TGAAGGTATG TTGCATTTTG CTATTCAATG AATAATGACA AGTAATGATC ACTTAAGACA TTAAGTGGTC AGTTCCTTTA CTAGGATAAA AATAATTTTC TTCCCAACAT GGGGCATATT CCATTTCCAG TCTGACTGTT CTGTGTAATC TTTGTATTCC TTGGCAGCCC

CTTTTATATC AGTTCATCTA CTGTGCAGGA AATTGGACAA ACATTTGCAC TGGTATAACC AAATACAGTT GAACTTTTGG CTTGACTCTT AGCTGAACTC ACCAAAAATA ATTTCTGTAA GAGACTGAGA CGTCTACGAG TAGGTTTTTC AGAATTAGTA AACATAAATC AAGGATACAC AGGTAGATTT GAATTTCAGA TAAACAACAA ATACTTTTTT AGTATGTCTA CTGAAATATT TGTATCTTAT CTGGCAATTC TACCTGGTAC AGAACTAATC CATTCTCTTG AAAGATCTTG ACTCTGTAAT AAGTTCTTTG GTGATGGAAG GGAGGTATTT CTGTAATTAG AGTCACTGTC TTCCTCCCAG TTTTTTATCC TGGCCCAGAT CTGCAATGAA CACACGACAG AATCCAGGGG GGATGAAGAT GGGTGCTTTG CAGGAAAAAA AAATTAAAAA CATCTGAAAA AGCTTTTGTA CTAAAAGAAT GTGATCTAAA AAAGAAAGCA GGAGAACTTT CTGTCTGCAC TTTACATCAG AACAACCTTG

GCGTCTAGAA GCTGTGCCCT GTGGGAAGTG GTGGTGCTTG GTAAGAGATG CCAGGACCAG TGGTACCCAC TGGGAGCACT GCCAATACCC AGCAAGGAGC ATGGGTGCAC AGTAAGGCAT TGCACTGTGA TTCAGCATAA AATAACAATA AGGGAACGTC ACGGAGAAAA GGCCAGACTT CCTTTGTTTA GAATGTGGGA AATGTCTTCT GAAAAATGGT AGTAAAAAAG CATGCTTGGA TGGTCCACTC CAGGCAAAAC TGACTAATCG GGGGTCAGGG ATACAACCCC TGCATCATAT GTTTGTTTCT GTTGGGCTGA CATGAGGTTC ACTGTGACCA CTGTGGTTTA ACCCCATAGT CTCCTGGAAA TACAGCCAGG TCAAGAGAGC TCCACATAAA ACATAATCAA AAAAATAAAC TCAAGTTTCC ACTGATCAGC TTTTCACAAC TCTTATCCTT TCACTAACTT TGGAGCAAGA TTTGAGAATT GGATGGCTAT TTGAGGGCTA TTTCTGCGCT TTAGTTCAAT GTTTTGTTCT

TTCTTTATTA GAGAACTATG GTTTTTTATT ATATTTACAC TTTAAGTTCT AGGGTACATG TGCACAACGT GCAGATTTGT TACACAGGTA TAAATGTGCC ATGTTGGTTT GCTGCACCCA TCAACTCGTC ATTTACATTA GGTATTTCTC CTAATGCTAT CCCTCCCCCA GTCCCCCACC CCCCGACAGG CCCTGGTGTG TGATGTTCCC CTTCCTGTGT CCAAGTGTTC TGTTTATGTG ATAGATTACG TTTATTGATT TGTGTATGTT GAACCAGCCT TGCATCACAG TCACTTGCTT ACAAGAAACA AACACTTCAC AGATGGATCA TTATGTGTGA TAAGTGAAAT CCAAGGATTT ATGCTCAGAG GTGGGCTTAA CAGGTAGGAA GAGCAGTATT TTCCTTCAAC CATGAGTGTA TGCAGGTTTT TCTTTTCTTT TTTGAGATGG AGTCTCACTC TTTTACCCAG GCTGGCGCGC AGTGGTGCGA TCTTGGCTCA CTGTAACCTC TGCCACCTGG GTTCAAGCAA TTCTCCTGCC TCAGCCTCCC

AAGTGGCTGG GATTACAGGC ACCTGCCACT GTCTCCGGCT AATTTTTGTC TTTTTAGTAG AGATGGGGTT TCACCATCTT GGCCAGCCTT GTCTTGAACT CCTGACCTCA TGAATCATCC TTCTCAGCCT CCCAAAGTGC TGGGATTACA GGCATGAGCC ACTGCGCCCA GCCCACAGGT TTTTCAAAGA CTAAACTTAA AAAAAAAAAA AAAATTTCCC AATGAAATAT AAAACTAAAG TGCTAAACTG TGATAGACTG TTTTACAAGA ATGCCAGTTT TCACAAGTGT CTATAGAACA TGTAATTTAG ATAGGTAAGA TGAAATTTTG ATAATATTTG ATGGCAAATT TAAACAGGTA TACAACAAAA ATAAAATTCT AAGCCCCTCA ACCAACTGAA TGGACTCCTT CTCTCAGCCA AAGGAATACC AAAGTAAACC TGAAAAACTA GTTTTGGCCA GGATTGGGGG TAGGTGGGGG AAGCCCAACA TGACTCATTA TTCTCTGCTC CCTTTGGAAT TCAGGCACAA CTGAATGTCA GCATTGACAC

TAAAACACAG ATCTTAAGAC TGACAAGCCA GACTCTTTGT AGCAGAGAGC CAGGCCCTGG AAGAAATCAA GTTATTTTAT CCCAAAAAAT ATTTCTTTGA TATATTTTCA AATGGCCCTG CAAAGCTGTC TCTTGTGGGG AAAATTGACA TGCTGTACAG AATTTCCTTC TCTTTCCAAG TTTTTACTGA TCCAGGAGAG ATTTAACTAA GAGGCTAGCA TGTTTTTTTT x x xxx x XGAGGCGGAG TCTTGCTCTG TTGCCCAGGC TGGAGTGCAG TGGCGTGATC TCAGCTCACT GCAACCTTCG CCTCCCGGGT TCAAGCGATT CTCCTGCCTC AGCTTCCCGA GTAGCTGGGA TTACAGATCC ATGCCACTAT GCCCAGCTAA TTTTTGTATT TTTTGTAGAG ACAGGGTTTC ACCATGTTGG CCAGGCTAGT ATTGAACTCC TGACCTCGTG ATCCGCCCAC CTCGGCCTCC CAAAGTGCTG GCATTACAGG CGTGAGCCAC CGTGCCCAGC ACAAGACATT TACCGTCTAT TCTCTCTGAA

GCTACTATCT AGAGGCTTCA TCAACATAAT AAGACCCTTG GTCTCCACAA CTCCTTATCT TATCCTATTA GTTTCTACTG ATTCCAGGTC TTTAGATAAT AACAACTCTT TCAACCAATT GCCAATCAGA AAGTCTTTGA ATCCACCTAT GACTTAAAAG CCCCACTCCT TCAAGTTATC CCGCCTTTCT GGACTGAACC AATGTACACC TTATATGTGT TGATGGATAT CTGCCTGTAA CTTCCATTCC CCTAAAATGT ATAACATCAA GCTGTAACCC AACCACCTTG GGCACATGTT TTCAGGAACT CATGAGACTG TGTTGCAGAC CTTGGTCACT CATATTTGGC TCACAGTAAA CTTCTTTAAA TATTGTATAG AGTTTGGCTT TTTTCATTGA CACAGGAAAA ATAAAGAATT GGAAGGTCTT TCATCAGTCA CTGAGCCAGC TTCATATCTG ACTGAGGTCA TACAGTTCAG TGATTTGTAG CTTTGCTACT TAGATTGCTA TCCATTATCT AGAAGCATCA GGATCACGTG GGACCTATTG

GAAATGCAGA CTTTCCTCCT AGAACCCAGG ACCTTGGAAT ATTCTTGGCA CATAGTAGGT GCTCAATACA TATTGAACTC CTAGGTGCAA TTCATTAATT CATGAATTAA TGAATTAACA CGCTCTCAAA GTTTAGTGCT TTTTCACAGA CTAGTCTTTC TGCCTCTTAA GCACTCAGCT CACCACGCTT CCAGTCTCAC TCCCCTATTA GTCTGATTAA AATCTGCTTA CATGTGAGTC TGAGATCAAG TGTTATCTCT TCTGAGAAGT CTTCCCTCAC TGGCCCAAAG GAATTTCTCC TCTATTTTAG CACTGTCCCA GTTGACTTGT CATTATTCTA GTCTTTTTCA TATTAGTTGT TTTTCATATA TATGTTATTA AGGAAACTAG TCATTTCCCC TAATAGAACA AAATTGCTGG CCTTTGGGGT TGGCAATGGA GGGGAGGCTC TTCTTGAAAA GGGGGAAGAG TGTTCTCCTA ATATTTTTCT TACGAGATTT ATGTTGCTCA TCTTTAGCCT TTAGTCCCCC ATTGCCTGCC TACAGTTGGC

AGAGACCATC TGTTCTCTCA CTGTCAGGAA CTGTCTCAAT TCTTGAAGTT CAGAGTCAAA AAAGAAGCAA GTTTTCCTAG CTCTTTGATC AACTTTCAAA GTTTTACTTC CATTTGAAAA TTTACTAAGT CACCAGGAGA TGGTTTATAC TGAGAAATAT CCACTCATAC TCTTCCTCTT CAACTTTCTT CCATATACAC CCTATTACAG GGATATAGTC TTACTCTATA GCTCAAAAGG ATGACCCTAT CAGAAACCTG CACAGTATGT AAAACATTCT CACCAGAGGT TCACTTGTGT ATTTCCACCC TAGAATGGAA GCTCTACAAA AGCACAGAAT GTATCATTTT AACTTTAGAT TCTATTTTCA CACCCAGTGC TTGACACATG ATTTGAAGTT AATATTTATT TATCAAGTGA TTGTTTTAAA ATCATGACTC ACTCAACAAA GTTATAAGAA TAAGAATAGT GTTACAGAAT TGGTATACAC AAGCTGACCA TAATCAACAC ACCTATTATC ATTTTTTTGC GACAGGTTCT CGCTGTCTCA

CCCTGGCTGG AGTGGAGTGG CATGACCACG GTTCACTGCA GGTTTGAACT TCCAGGCTCA AGCAATCCTC CCACCTCAGC CTCCCACATA GCTGAGCCCA CAGGTGTGTG CCACCATGTC CAGCTAACTT TTTAATTCTT TGTAGAGACA GGGTCACCCT ATGTTGCCCA AGCTGGTCTT GAACTCCTTG GCTAGAGAGA TCCTCCCTCC AAGGTCCCCC AAAATGCTGG GATCTCAGGC AAGAGCCACC ATGCCTGGCC ATAATCAATA CACTTTTAAG AATGCTAGAA TGTTATATCA GATGCATACT TCAGCACTAT CTCAAGCAAA CTGGGGTGTG GGTTATTCTA CATATAAAGT TCAGCAGTGT TGTTCCACAG TCCCAAACTC CAACTGAGGT CAAATGTAGG GTGCAGCAAG GTCACTGGGG CTGTCATCAA GGGCCTCTCC TTGCACTCTT GCCAACCCTG TTTCTTGATT GTCTCTACCA CCATGAGTCA CCAGCAATCT CCCACAGTCA CTTGTTTAAA AGTTCACAAG TATTGTGTGA

ATTGCAGGCA ACCCCTTGAC TCCCTGATTG CCTGGTCTTC TTCCTTGGGC TCTACCATTT TTTTTCCCCA GCACTCTTTC TGCTGCTCTA AATTTTAATT CATGCAATTC CATATGTGTT TCTCTATCAT TCTTCATCTC TTTCCTCTCC CTTCCATCCA ATTTTGTTTG TCTGTTTGCT TGCTTGCTTG CTTTAATACA TTTCTCTTTT TCTGAGAAGG CTTGAGTCCA AAACTCTCAG TTACCTGTTG TTCTGTTTCC CGTTAGTTAA TCTCCGAACC TTCATAAATT AAATCTGACA AAGTCCCCTG ACTAACAAAG GAAATGCACA AGTCACAGTA AAAGGGGCAC ACACAGAACA CAAATAGACC CAGGGTCTTT TCTGTTCATC ACTCAGCTTT TTATAGGAGA TCCAGGAGAA ATGAAGTGGA AAGGGAAGTG TGTTGAGTTA CTATACAACA CAAGAGTAAA CTTTCTTATA AGTGGTAATT TTTTTTTACA GGAATAATTG AAAATGGAAA TTACCTTCTC TACTCATAGT AAGTACTCAG TGCGTTCTTG ATGGGATGAG AATGTGTTTG AGCTTTAGTG TAAGGCAGAA TTCTGTTTAG TCTGCCAGTA TTGGAGAAAA ATAAAACACA AAGGGACTGA CATGTAGGAA GTGGCACCTG GGAGGGTCTC AATTCTTCCT ATTACAAAAA TGCCCCAGAG AAATAAAAAG CTTGTGTACA TGTTGAGATG GGAGAGTTCT CTGGCCCCCC TCGCAGGATG TGTGACAGTG GGGTGGCTCT CTGCTGCGCC ACCATGAGCT CAAACCCCTC ATAGGAGGGG GAGCACACAG GCAGGAAGGT GCAGGAGCTG GGCGAGCTCT TTGGGCTCTG GCCCCGTGGT ACTGTCTAGA GGTGGGTGCC TGCAACTCCT GAAAGCCCAA GTGGGCATGT GTTACAGTGC ACTCTTTCAG CTTTGCTGTC TGCAGCTTAA

GCGTTAACCA GCTCAGTTTC TTCTTGGTAC CCAGGTCCTT GTCTGGCATC CAGGAAGAAT CAGGTTACAC ATGGACTTGA AGGATGAATG TGGGAGTTTT ATGGAGTGGT GGAGGTGGCT CTCAGTGGGA TGGATGGGGA GCTGGAAGGG GGATGGAGTG GGAAGATGAT ATTCTCCTGG AGTTTGGCTG TCCAGCAGCC GATCTCCTCT CCAGTCGTCC CCAGCCTCTC GACGTTCAGA TGCTCCTCTT CTCTCCTTCT CTGCCATGCT GTTCTGCCGT TCATCTGCCT GTCTCTCTCT GGAGCCTGGA ATTTGGGGTT TATATGGTAC ACAATAAGGG GCATGGCAGG CCAAAAGGGA ACTTTTTAGG TGCAAAAAAC AGGAATGCCT CTTCTCACTT AGGGCTATAG ATTTTCAGGC TTGAAGGTGG GGCCTTTACC AGCGAACCTG TATTTCCCTG TCTCCTGTGC ATATCAATGT AATCAAATAC TGGGCTGATC CAGGATGTTT CTTTAGACCA ATTATGGGTA AAATAATTTA CATTCAGGTT

TTTATATTTG CTTTTGTCAT TTCTTTTTAA GCAATCATGT AAAATATCTA TACGACAGTA ATAGATGATA GCGAACCTAA TTAAAATTAC CAGAAACTTA AGAATCTCTA ATGATTTCAA CTGTAACTAA GGTTATTTCT CTTTATGTTG AACAATGTTG GGAGATAAGA CACAAGAGTT TCTGAAGTAT TTCAGAAACA CAAAGAGGGA GGTTATATAA

ATAATATTTT TTTCCTACTT

AAAATGCAGA ATATTCAAAA CGTCTGACCA CCCTTCTAAG AAAATGCATC TCTGAGGTAT TTTTCCTTAG AAGTTATTGT AAAAATCCTG GAGAAGCTTG AACACAGCAA AGCAAACAGG ATGCAGAGTT TAATCTGTGG AAAGCTTAGG GAAGAAAAGC AAATCATTAA AAATAGGTCT TCCTCTGAAG ATTTTTAAAA CGCAAAGAGG GTGGAATAGC

AATGATAATA AAAAAGCTGG CATAGAGAGT GGCACAATTT GCTGTGCCAC TGAGCTGACT GGATGTGTTC TGAATTTCTA GGCATTAGTG TACCTTTCCA CACGCATTCT CCCTTTAAAA AAAATGCCCA CACACTGAAT ACTTTTTTCA TGCAATTTAA AATAAGCGCA CCATCTAGTT TACAGAAATT CACTAGAAGT TATTTATCCT AAAATAGCAG AGATCTAGAA GAATTTTGAG CTCTAOGACA TTTTAGACAC ACAGAAAGAA GAATCTGGAC AAGTCTTGAC CAGACATGAC AGAATAGAAA TTTCTTTTCC TATTTATCTC TTTGAATAAA ATTTTCAGGA TCTTACAGTG GACAAGTTTG TTATCTACAC ATTGTGAAGC ACATTGATTT CTCCTCTGTA GCCTTAGGAA GATCTGAGAG GTGACTGAGC TGATTGAATG ATCCGTGACC GCTCTACTGG GACCAGTAGT AGAACTTTAC TGGTGGAGAC CTGCTGGAGG TTTGAGAGCA GACTTTGAAA ATTACTAGAG CTACACAGAT

ACTGTGTGGC TAACTGGATT ATGTTTAGAG GCTTTCAGAA CTATGCTGCT GCTGCTGCAG TGTAGCCAGG ACGCACAGAG AACATCTAAG GCTCTTGAAT GGGGCGATAG GGACAGATTT CAGCAGCCAT CTGACTTCAG TGCTCATTTT GATGCTTTCC CTGCAGGGTG CAGTGTGCAG TGTGCAGTGT GCAGTGGTGG GAGGCTCACA CAGGAATACT TGCTTCTGTA GCCCTAATTT CCGGTTCAAA CTCTGCATTC ACCTTGACAG ATTCTTTCCT TGGCCAAAAT TTAGTTAGGC TTCTGGGCTT TCTCTTATGC CCACCTGCAG ACTTTTTOGT _{AAAAΥC AGτ} xxxAGTAAAG AGCTCTGCTA AGTCAGTTTA GCAAGAATCC CCACCTCAAA AGTCACTATC TCCCTCCCTG GTAGTGTCTG GCTTGTCTTC AGCGAGAATT CTATTAGGTT CTGTTAGATT AGAATCCTCC TTACCCTTGA TGCTTCCTCT TAGTATTTTT TCATCCACTG ACTCCTTGAC CCACCTTGCT CCTCGGCTAT

AAATTCCCAC TTGCCCATAC TCTGCAGTTA AGACTATTTT CTCCCCACTA CTGCAAAATC CCATTGCCAT GGTCCCTATA CTATCTCAAT GGTAATGAAT AAAGTCTGCC TTACCATGCT TTAACAAGTA ACATTGAACC ATTTTTTTCT TTAACAATCT GCTGCACAAT GAGATTACTA AAACTTTATT CCATTTTGCC ATGCTGGATG TCCTCAATGG AATGGCTCTT GTGAGCACCA AATCATTGTG AGAAGGAAAA CCCATCTCTT ACAGCCCCCT GTAACGTGAT GTATGTTACA TGTGATGTAT GTTACATAGT TTTTTTTCAT GTTGATCACT TTTTGCCCAT TTTCCTATAT CTTATCAGTT GGAAGACTGT GGAAGTTTGT AGTACTAAGC CACAAGATGA CTAAGAAGAG TTGAAAGGGC AAGTGGGGCT AAAAACAGAT TTTGTTTGAC TTACCCCACC ATTCCCCCTA TCATGGGGCT GAATCTGCCT GGAGGAAGGA GCATCTTTAT CTTTGTACTG TGAACCACAC AGTCTAGCAG

CAGCACAGCC AAGGCACTTG GGGTTTCATG AGACTAAGTA CATGCAATTC TATTGTAAAG GCTTAAAATA TATACAACTG ACCCTTGAAC AACATGAATT TGAATTGCAT GGTCAGTTAT ACGCAGATTT TCTTCCACCT CTGCCACCCC TGAGACAGTA AGATCAATCA ATCCTCTTCC TCCTACTCCT CAGTCTACTC AAAGATACTT GAAGTCTACT TGAAGATGAC AAGCACAAAG ACATTTATGA TGATCCACTT CCACTTAGTG AATAGTAAAT ATGTTTTCTC TTCCTCCTAA TTTTTTAACA CTTTCTTCTC TCTAGCTTAA TTTATTGTTA AGAATACAAT CTATAATACA TATGACATAC AAAATATGTC TTAGTTGACT GTTTATGTTA TCTGTAAGGC TTCAGGTCAA GAGTATGCTA TTAGTGGTTA AGTTTTCGAG GAGTCAAAAG GTGTATGTGG ACTTTCAACT GCAGGGGGGT GGGCACCCCT GCCCCCATGT TGTTCAAGGG TCAACTTTAC TGCCAAAGGC AAGCCTTTAC

ATCCACTTTT TCCATCCCAT CAGTAAATGG AAAAAGATAG CTACAGTATC CCTGCGTCAA ATCTTTTTTT TTGCAGATCA CAAATTGGCC ACTCACCTTG CTCTGTGAGG GGTAAAATGC CCCACTTTCT TTAGTAATAT TTAAGTTAGA TAATATTTAA GTTATAAAGT TGTTCTTTGT AATCGTTAAT TGTAATTTTT ACATAGTTTC TTTCAAACAG AAATAGCATT TTTGTTAGAT AACCTCCCGT ATAGATGATG AAACTCCTTT TAAGGGCTAT CTGAATTTTA ATTCCTTGAA AAGGCAGAAA TTGGATAGCT AGTAGTCATA AATGTACTGT GGCTTCCCCC AACCATCTGG GCTATATAGA AGCTGCATCC TTGGACTGCA GTAGAGGAGT CTTACAAAGC ACAGAGCAAC TTCTCTCCTG GGTTGCGCTA GTTATGATGG CAATTTTAAA TGTGTACTTT TACCCAAAGA AAATCCTTAT TATCAACAAT CACAATGCCA TCATAACCAT GGTATAAAAA ATTCAAAATG TCCCAGCTGA

AGTGGAGGCA AAGACTCAAG TTCATGGAGT CAGAGTTTCC TTGCTATTCC TCTTTTTCAA ATGACCATTT AGTAAGCACC TGAAGAAAAT ACTATGGACG GCATTGAAAA GTGAAGATAG GTTTAATCTT CTCGAAAATC TAATTCTCCA GATGAAACGC TGACACTTAT CCACCCCACA GACCCTATAG CAGATGTGTC ACTGGCCATC ACATTTGACA CAGAGAAGTC ATAACTCAGT CAGCACAGAG ACATTTCCAT GAGTTTCTGA ACCATGGACA GAACGTCGTC TGTGGGACAT GAAAACTGGA ACTTAGAGGA CAGGCACATC TGAGAAATGG GCAGTTTAAA GGCAGAACAT AGCACATATG TGACTGGGTT TTAGAAGCAA ATTTACAAGA CGCACTCTTC TTCATCCTAA ATAATCTGCA ACCAAAGCTT CCAAAAAAGA CAATTTAGGA ATGCAGAGGT GAGGAGTAGG GAGGGGAATG GGATGAGAGA GAGTGGAGAT TAATGGTGGG CAGAGCGAGG TTTAGAACTT

AGTGGTTTCT TCAGGTTCTG AACTGAAATT TGTATACTGT AAAGGCACAA ACACCATTTT TAACAAAAGT GAGCAGGACT TCCTATCTGG TTCAGAAAAT AGGTGAATAA ATAGTACGAA TTATTAAAAA TAATAATTTC CACTTATACA TAGGAAACTT GATAGGAACC ATGATAAATG CTTAACTCTT AATCTTCAAG GAACTCTGCT AGGGATATAA TATTATAAAT CTTGTTTTGC AGATGGAGAA ATTGAATTTT AACCCAAGTT ATCATAACCC TTAAATGATT AAATGATACT GTTACATGAG AAAGCTGCGT ATCTGTTTCC TGGATTTGTA GCCATAATTT GTGTCTCAAG TCCCTTTTGC TGCCAGCTAT CTTGGGTAGG TGTGTTCCCT TTGGGCTGTT TGATACCCCC ACATTTATCT TTTTTTTTTC TCTTTTTTTG TTGAGAGAGT CTTTCCCTGT TGCCTAGGCT GGAGGGCAAT GGCGCGATCT CGGCTCACTG CAACCTCCGC CTCCTGGGTT CAAGTGCTTC TCACGATTCT

CTTGTCCCAG CCTCTCTAAT AGCTCGGATT ACTGGCATGC ACCACCACGC CCACCTAATT TTGTATTTTT AGTAGACAAG GGGTTTCTCC ATGTTGGTCA GGGTGGTCTC AAACTCCTGA CCTCAGGTGA TCTGCCTGCC TTGGCCTCCC AAAGTGCTGG GATTACAGGT GTGAGCCACC ATGCCTGGCC CCAAATTTAT CTTTAATGCC CCAAATTATC TAGTTCCCAT GACTGGGCTT CTGCTTTGAT CCTTTCTGCA CTTGCTGGAC CCTCTCCCTG GGAAATGAGA TTGTGTCCTG AGCCCCTAGT TAGAGGCTAT GTCTCTGCTG TTCCTGAATG GGCCTCCTGG ATGAGACCTC ATTAAAAGTC TAATTCTCTT GGAGAATTGA GAGATACCTA TTTGTCTCAA AATCATTGAA ACCAATTAAT GTATTATGAG CCTCTATCCA GTGATTTGTA CCTCAATTCC CCAATCCAGC TGTCAAGGCC AATTTGTTCT ACCTTACCTA GTAGGTAAGT CTGGAATTGT AGCTGTGGCA TTTTCAGTAA

TGGTACTCTA GGTTAGCAGT CCCCAACCTT TTTGGCACCA GGGACCAGTT TTGTGGAAGA CAATTTTTCC ATGAAGGGCT GGGCAGGGGA GTGGTTTCAG GATGAAACTG TTCCACCTCA GATCATCAGG CATTAGATTC TCACAAGGAG TGCGCAAGCT AGATCCCTCA CACATGCAGT TCACAATAGG GTGTGCACTC CCATGAGAAT CTAACACCGC TGCTGATCTG ACAGGAGACA GAGCTCAGGC AGTAATACTC ATTTGCCTAC CGCTCACCTC CTGCCGTGCA GCTCAGTTCC TAACAGGCCA CGGACCAGTA CTGGTCCACG GCGCAGGCAT CAGGGACCCC TGTTGCTAGG TATAAGCATC TGGCTGCTGC ATGTCTTCTG TGTAGCTACA TCTGTATGTG TATCTGATGA GATATAAATT ATTTGATTAT AAATTACTTT CTTCATATTA GAGTTGTGAA TGAGTATCAC ATATAATTAT ACATAAACTA GGAATATGCT TTTTAATAAT GTATATAAGT AAGTTTCCTT AACTATGACT

TTCATCTTAG CGTAGTAAGA GGGTGCTAAG AAATATTTGT GATGAAAATA GGCATTGGTA GAGTTGAGAC CACTGGGTGA TGAAAGAGTG TAAAGATTTT AAAGCCTTCA GATGCTGGTT CAAGGTGAGA AATGTGATTG GGAGCAAATC AATTAACTTC TTGAAGTCTT ATAGGGCAGT TATGAATACT TAATGTTAAC ATATGTAAAG CTCTTCTGCC CTGTATACAG TAAATGCTAG TTAGCTATTA TGATCACTAC TAAAATGGGG ATGACATAAA CCTCATAAGG TTTTAAGTAT TATGCAAGAT ACTATACAAA GTCCAGTAAA TATCACATTC AATTGAATCC ATGATGTCCG ATTATTTTAG CTACTTCCAA GAGAGAAAAA AATGCTGTCA GTTTTACTGT TCTTATAGAG AGCAAGGCAG ATCCCAATTC CCAATGTGGT AACGTGAAAA TTTTTGCATT TGAATCAACA AAACACTTTC TCCTTTCTTT CCTACTATTT AACAACTGGT AAGTCTATAC TCCCCCAAAT CTGGAATTCT

CCTTTCTTAT TCTTTTTCCT CCTACCAAGA CCGCAGGATC TTTTACTTGG CTATAAGGGG TAAACCTCAA GTAGTACAAG TTCTCTGTAT TACTTTTATA CTCTGTCACA GATTCCCTTT GTTTCCTCAT CTCCATGTGA ATTTAGTTAA ATTCTCAGCA TTCTGATCCT TACTATACAA GGTAAATGAA TATAAAAACA AAACGAAACA AAAACCTCTT CCTATTTACA TAAGGCCCCA ACCTAATATT TAGTGATATA TATTAATGTG AACAAGGAAC TAACGAAGAC TGGGAAGAAA TTCACAGACT TGAGAGAAGA AATGGCAGGA TTTCCTGGGA ACAATTTCAT GTAACGTCAA AGGTGGTAAA AGGTCAAATA GAATGAAGAT GGAGAATACC GGATTTTCTT ACAAAATGAT TTCCCAGGAG ATCTCATCAA ATGCACGAGG ATACCTTCTC AGTTTCACCT AGTGAGTAAA AGACTGGTAA CATAGCTCAC TTACAATTTG GATAAACAAA ACTAAACAAA CAACATCAAA ATTTCAGAAA

AAATAATAGC AAAACAGAAA TCAAACACTC AAATTTTTGG TCCTTCTGTT TATTTCATTT TGGATACTCA GTGAATGTTA ATTAACCAGG AAACTTAAAA GTTATTTCAA TTATGAACCT CTTCAATCCT TCATCAATTA TTTTGAGTAT TCTGGTCTTA AAAACATCTC TTTCTTCTAC AAACTTCTGA AAGAGATGAA CACCTCCACC TACACCAAAA TAATGTGCTT TGCTGGCCAA AAGTACACGT CCATTTTTAC TTAACAGTCT AAGGAAAGTC TGGTGCAAAT TACTATAATA ATCTGGGTTG TAAATGGTTT CTGAGGTGAG AATGAGATCA TATTTTACAA AAAGTTTTTC ACTACTTAGT ACAAGCTTAC AAAACTCAGA CCACTCACCA GAAAAAAATC GGCATTTATA TAGTTGTGTT ACTTTTGGTT TCCTGCATCT TTTCACATCT GGCTCATTTA CATCATTTTC TTCATCTTCC AAAGTGGAGT TAGCTACTAC ATTAGGTAAG GTTACTTCAT CAATCACCAT ACTGTTATAA

TCTTGAAAGT GAATTTCTTT GGACCCTCCC TTGAATGCAG TTATACCTAG TAAACCTGAT CCACAACCAA GATCCAAGAC TTTTTTCCCA GCAAATTTCA CTTTGGCCTT TGTGAAATAA GCCAGGAGGT CAAAGGTACA TTCCCAGATT TTTAAGCCTC CCTCATAAAC ACCTGTAATC AGATCAGAGT GAGAAGAAAA GCTTTTTGAA ACTATGTTTT CTCCAGGGAA GTTCTCTTTC AACAAGATGG TTTTCACTAC TGATAACTTA ACATGCTGGA AACCTGGTAA TGTTTCTATG ACTTTATTTT CTAACATCTT CTTTAAATCT TTAGGCATAG CATGCTCTTT GGCAGCTCTC AAGGAGGGCT GTTTTCCATG TGGCTCCAAG TTCCTTGAAC TGCTGGCTGC ACTGAGTGGA CTGTCTGTGT CTTGAGAGGG AGCTGCATTT TCCATTGACT TATGTTCCCA CAAGTGATCC TGAGGCAAGT CAAATTGTTC TGCAGAACAT TTTCTGTCCC TCTCTTCTCC TTTTTGACTT TCTGAGACTG

ACAGCTCTTT TGAGGAATCC AGGGTCAAAG CTCCATCTCT AATGGGTGTT AATTCATTTT CCAGATGGTC TTCTATAGTG AAATTAAACT GAAAGGTCAT CCTCTTATTA AATGCACACA ATCTTTAAAT TCAGATTCTT CAACTTCTGG ATAGAATTTG ATGATACACA CAAATCTGCC TCAATTATTC AATTAGTTTT GTTGGGCCCA ATTTCTCTTT AGCAGCTTAT ACATGGTAAC AAATATTTAG AGATATTTCC AAATGACTTT TTAGACGTCT TTGGTCCTCT TTCCAAGCAG CTCTGGAAAG AAAAAAAAAA AAAAAAGAAA GAAAATGATG ATTAAAGCAA AATGGCACAT TTCACTAAAG TGTAATATTA AACAGCCACC CCCACCCCTC CCTGTCCCAC CATACAGCTG CTTTTTCTTA AAAAGTTGTG GGGAAGAGAG AGAGATAAGA GATTTGGACA CTCATACACA CCTTAAGGGT TCCAAAGTGG GAGAAGAAAA TCAACTATAA AAACAAACAG AAGAACAACA

GCAACCACCA CCACTACCAC CTGGACAAAC ATAAAGTCCA AGATATTCAG ACAGGACAGC CTAGCTACTT GCTGTCTTTC AGCTGTCTTG ATTTGTGTCC AACCATATTC ACCCCCTAAG CTTCCAGAAT AACTTCACTT CTGTCTTTTA CAGAAGAGGT GCAGTATTTT ATTTTGGTAA GTCAGCGTCC CTTTAAAAAC ATGCATAGGT ATGGCCTGGT GTGTGTAAAT TCATCCAAGA CTTCACTCCA AACATTTAGT CGAGAACAGC AGCCCTAAGT GTATAGAAGT GGGGGTAATT TGGCAATAAT TAGTAAAGAC TAATTCGGTG GCAGAGCAAA CGCAAACTAG GGCACTGCAG TAGTTTGGAG AGACCTGTAG AAATAAGAAG CAACTTTATT GAGAATCTTC TATCTACTGC GCTAGACACT ATACCATCTG CCTCAATTTT CACAGTTCTG GCAAGTGGGA TCTTTGTTCC CTTTATACAA GATTTACAAT TTGGGGGAGA GGCGGGTCAC CCAGTCCCGC GGCTAGGAAC GCGCCTCTTT

CCTCTCCCAT CACGCTGCAA GGCTTGGAGT CACTTCCGGC TGCAGGTCCC GGAACAAATC CGACCCCAGA AGTGGGGACT TCTGGCCCTC ACCTCCCCAT TTGAATGTAA TGTTTACAGT GATCCAGACC TGGGGATGCT TGCTTCCCGA CGTGTCCTGG GATCGCGCTT CTGAAAAAGC TCACCTCACA ACGCCTCCTC CGGACCTAAA TCGCGCACCA GTGAGTCGAG TCCTCCAGGG GCTAGAGAAG CCCGACTTTC TTTCCGGCCT TGAGGGACCC GGGCTCACCA AGAAACCAGC CGCCCTCCTC TCTATGGTTT TGGAGCCGGC GGAGAGCGCG CAAGGGTTGG CGGGACTGCG AGTTTCCGGT CTGGGCTTTG GCGGGTCTGG TTTGAAGCTC TCCTGTTTGA CGAAAGTATG TCTCAGGAAG GTGCGGTCCC AGCTAGCGCG GTTCCCCTGG AAGAATTAAG TAGCTGGCCA GAGGAGCTAT GCCGCCGGGA ACTGCCGTCC GTCCTGCCCC GACTCCTCAT ATCCTTCCTT GGTTGTCACT

TCTACCTAGA GAAGGGTGTG GGCGGGTCGC GAACCTTTCT CTTCTGTCCC TTCAGACCCA CCGCCAGGCT GGGTTATATT ACCGCGGCCT GAACCCCCTC TTTTCTTTGT CAGTGAGTGG GATGAAAAGT GAGGGACTGG AGGGGAAGCG ACAACCGTGG TAGATTTAAG TAAGGCTTTG GCCCTGGAAA GCCTCGCGGA CGTGTTCTGA CCCAAGGTTT TAGCAGTGGA TGTGGCGTTT TCTTCCATTC CTTCTTTCAG TTTTTCTGTA CTCGTTGCTT GCAATTAAGT GTAAATACTT TTGCTAGTGG ATAATGGGGG AGGCAAGGAC TGAGACCTGC GGTATGACGA TAGCTCTGGC TCTTAATAGT TTGAGGTAAA GCGAGATACT CTGAGCTTTT GTCTCCCGTA AAAAGGGTGG TGAATATGAA TAAGGGCTTT CTTAGCGTTA TAAGAATTAA AGGGCATAGT TCTGTGGTGT GAAATCTTTA AAAGATGTTC AGTAAATAAA AATGATTTTC CTCCTTCCCC TCTCAGACCT CTTTTTCTTC TTTCTTTCTT TTTTTTTGAC AAGTTCTCAC TCCTCTCACC CAGGCTGGAG TCTTTCTGAA AGAGTTCTTC CGCTTGTTGT TGGCTTTCAA CTGTTGGATT TGAGGCGCTT AGCGCCTTCT TCGTCCGGGT GCAGCACATT CTTGATTGGT CTCATGCCTT TGTGGTTGTA AATGTGCCTG GAATCCTAGC CTTTCATGGT AAACCATATG TATATGTATC TTTTTCACAA CATTTGAGCC CAGCTTTATA CAATTACACT CAAAAGAAAA AAAGTAACCT TCACTTGAGA GAATCTCAAT ACTGCACAAA TATTGTGCAG CTAAAGCCCT ATGTAATCAC ATAGAAGTCA TTCACCTAGG CATTAGCAAA ATCTCAGAAG GTGCCAAAGC CCCCTTTTTT AGTTTTTGTG TAGGTACAGA ACTGCCGTCT

TCAAGGAGTT TCAACTTGAA AACAAATAGC CACCCTCAAA ACATTCAAAA ACACTTAAAC TGCGTGCATA ATGTGTGTGA GACATGGTGT TAGGCTTTGG GAGAACAGAG ACACGGAACG TGATTCCTCT TCTTCCCCAC AAGCTTATAG AGAGACTTCA TTAAGTTGAA AGTCAACATT CCCACCTAGC TTTGCACTTC AAACGACATA TTCAAAAAAG CCCAAACTTC CTCTAGTTTT CTTCATCTGA GTAAATGGTT TCACAAACTG AAACCTTGAA TCCTCTCTGT CTCACACACC CGATCAGTAA GTTCTATTGT TTCTGATTCC AAACTATGTC TTGAATCAAT CCGTTTATCT CCATCCTCAT TGCTACCACT CTGATTCCAA ACCCTTATCA CCTCTCACTT GGAGTATTAA TAGTTTCCTT GTTTCTACTC ATAATTCATT ATTCCAAAAA AGTTAAGAGG GGAAAAACAT AGATCTCGTC ATTTCCCTTT TTAAACCACT TTACCTTCAA GGTTCCAGGT GATCTAAGCC TTGCCCTTCT

CTCATACCTA GTTAATTAAC TACACTCTGT TCATGAATAC ATTAGGCTCA CCTACCTCAA GATCTTTTTG CTCAGCCTGA TTTGTTCTCT CAGCCTTTTG CATATTTCAT GTTTATGTCT TGGCCCAAAT GTCACTTCCT TAGAGGGGCT TTTTCAGAGC CTTCAATCTT AGGCAGTTCC CCCAAACGCA GTCTTACACT TGTATCACAT TGGCCTGTTC AGTTTTCTAA AAAGCACATT ACCATTAAAA GAAATGCTCT TGTTTGCTTT GTATATTTTC CACTTCTACA CATTATGTTG CAAAGTTCAT AAAGGCAGGA TGTTGATTTT CTTCACAGCG TTACCCTCAG CACCTAGAAC AGTGCCTGAC ACATAGTAAG CATTCATTAA AGGGCTAAAA ATATTTCATG TTTTAAAAAT ACTTGGGAGT CTAATTAGAC AATACTTTTT TTCAGCTTAA TGGTAGTATT TTAGCTTCAC TATTTTAACA AATGAAAAAT TTGCAATAAA TCTACAATGC CATTACCCCC CAAAATCTTT TTCATGTTTT

GCATTTTACG TATTATTTTC CAGGCCTTAC CTGCATGTCT GCATAATCAT AACTGACTAA TTTTGGAACA GCTGGTAATT ATTTGAGCTT TACTGAAATT TTTTCATGAG GCCAATTCTA CCCTACTGAA CTCAAATTTG AGTTAATGAT GACCTCATTT TGATTGCTGC TGTAAAAAAT AAGATTTCGG AAGAGGAATG AATTCTTGTA TTACTGTGGT AGGACTATGG GTTTTTTTTT GTTTGTTTGT TTGTTTTGAG ACGGAGTCTC ACCCTGTCAC CCAGGCTGGA GTGCAGTGGT GCGATCTCAG CTCACAGCAG CCAGGTTCAA GTGATTCTCC TTCCTCAGCC TCCCGAGTAG CTGAGATTAC AGGCACGTGC CACCATGCCC GGCTAATTTT TTGTATCTTT AGTAGAGATG GTTTCACCAT GTTGGCCAGG CTGGTCTCGA ACTCCTGACC TCGTGATCCG CCTGCCTCAG CCTCCCAAAG TGCTGGGACT ACAGGCGTGA GCCACCGTGC CCGGCCGGGT TATTCATTTT TCTTATTAAC

ATTCTTTGAT GATTCTTATG GTGTTGTTAC AGTAAAACAT TTCTAACAAT TATTCTAACA ATTATTCTTG ATGGTGTATA TGAAGAATTT ATTGTCGTGT ATTTGTAAGC TGCTATGTGC AGAAGAATTT CAGTCAAATA AAGTTGGTAA GATAGGTATG TAAGTAATAT GAAAAAAGAT AGAAGGTGAT GAGTGACTTA GGTATAAATT AAGTACAATA GAAATGTTGA GGAAAGAAAA ATTTCTTGTA ATAGAAATCG GAAGTACAAA CTGGGCATGG TGGTGTGCAT CTCTAATCCC AGCTCCTTGA GAGGCTGGTA TGGGAGGATC ACTTTAGCCC AGGAGCTTGA GGCTGCAGTG AGGTGTGATC ATGTCACCGC ACTCCATCCT GGGTGACAGC AAGACCGTCT CTCTTTTTTT TTTTTTTTGA GACGGAGTCT CGCCTATGCT GGAGTGCAAT GGCGCGATCT TGGCTCACTG CAACCTCTGC CTCCCAGTTT CAAGTGATTC TCCTGCCTCA GCCTCCTGAG CAGCTGGGAT TACAGGTGTG

CGCCACCATG CCCAGCTAAT TATTTTGTAT TTTAAGTAGA GACGGGTTCT CACCATACTG GCCAGGCTGG TCTTCAACTC CTGACCTCTT GTTCGCCCAT CTAGGTCTCC CAAAGTGCTG GGATTACAGG TGTGAGCCAC CCCACTTGGC CCCGAGCGAG ACCCTCTCTC TAAAAAAAAA TAAATAAATA AATCATAAAC CTGTGGATTA TTGTAGCATT GTTTCTCATC TGTCAAAAAT ATTTCATGAC TATGCATAGT TTGAAAAGGC AAGTTTGTCC CTGGGCAATT TTCAAAATAT TTCTTTAATG TGTTTTCACA ATACTGTTTA CCTAATAAAT CTTAAGTTTT TAAAAGCAAA ATTAAGCCAG TAATTTGAGT CCAATTCCAA TCTCTTATGA GTCATTGCTT AAATTTCAAA AGGGTTTTAT TTTTTTTTTA GGTTTGTTCT GAGTAATGAA TACCCTATTA CTATGATACT AGTATCTTCC TTAATTATCC TACTCATTGT CTCAACATTC TGACAGTTGG ATTGAGCATA TTCGTAAGTA

AAATTGTTTT AACTGTATGA TGTACTTTGA TGTTAAGGTC CGAGTCCCCA CATACCTCGG TAGATGTGTT CTTACAGTTT TGTATTCCCT TGAAATGTAA CTGTTCTCTA TGTTACAGCC TTTATAACCT TCAGTTACTT GAAATGAACA AATTCATTCA AATTCCAGCA CTTAAAAGTT TTAAATTACA TTTTGGATAA ATACCAAAGT GTTTTGTTGA TGATGTATGT ATAAACAAAT TGTAAATATT AAACGTTAGT TGTTACGATT AGACCTATAT AAAACATGAT ATGCAGTCTA CTGAATAGCT ATCAGCCTCT AACATGTTTA GTGTCATTTA GAAAATGCTT TCTAAATTGC CAAAAGCTGA TTGTCTAGGT GATAACAAAT TTACCATTTG GAGGAAGTTG ACTTTCTCAT TTTCATGTCT TCATCAGTCT TACTTGATGA GATTCATTCT TCTAGTCAGA AGAGAGTTTA GACTGCTCAG TTTACTCATA TTTTGAGTTA GCTTTTCTAT TTAGAGTTCA CTTGGTTGTG GAATATTCAT

TTATAATTTG AATCTACGTT GTGTAATGGG ACCTAATTTT TTTTTCCTTT GTTTTTGTTG GAGTCTCGTT TTGTCACCCA GGTTGGAGTG CAGTGGCGTG ATCTTTGCTC ACTGCAACCT CCACCTTCCA GGTTCAGGTG ATTCTCCTGC CTCAGTCTCC CAAGTAGCTG GGATTACAGG CATGCTTCAC CACGCCTGGC TAATTTTTGT ATTTTTAGTA GAGATGGGGT TTCACCATGT TGGCCAGGCT GGTCTCAAAA CTCCTGAGCT CAAGTGATCC TCCTGCCTTG GCCTCCATAA GTGCTGGGAT TACAGGCGTG AGCCGCTGAG CCTGGCCCCA GAGTTTGTTT TGTTTTGTTT TCAAGACAAG ATCTCACTCT ATTGCCCAGG CTGGAGAGCA GTAGTGCGAT CATAGCTCAC TGCAGCCTGA ACTCCTGGGT TCAAGCTATT CTCCTGCCTC CATCTTCTAA AGTGCTGTGA TTACAGGTCT GAGCCATGAT GCTTGGCCTG TGTTTTTGTT TGTTTGTTTT GGGGGACAGG GTCTTGCTTT

GTCACCAAAA CTGGAGTGTA GTGGTGCGAA CATAGCTAGC TCACTGCAGC CTCCATCTCC CACGCTCAAG CAATCCTCTC ACCTCAGCCT TCCAAGTAGC TGAGACCGCA GGTGCGTGCT ACCATGCGTG GCTAATTTTC TATTTATATA TTTATTTTTT GGTAGACATG AGGTCTTGTC ATGTTTCCCA GGTGGTCTTT AACTCCTGGG CTCAGACAGT CCTCCCGCCT CAGCCACCCA AAGTGTTGGG ATTACAGGCG TGAGCCACCA TGCGTGGCAT AATTTTTTTT AAGTAAATTA TTTTTTTATC TTGAGTATAG AAGTGATTCA TGTTCATTGT GGAAAATATG AAACATATAG AAAAACAGAA AAGATTACAA AACATCTAAT CTGAAATGGT TAAGATTTTG ATGAGAACAG TCTCATCTCA TTTCCGTATA TTCCTGCCAG CCTATCCATC ATTCTTCGTA CATGTTTATC TACATTAAAA TTGGTGTTAT ATTTTGGAAA CTTTTTGTTT AACTACATTG TGAACATTTT TCATGTTTTA

AAATGTCATT TTAATGATGG CAGATCCTAT TCAATAGATG TACACACACC TATTTAACTG GTCCACAATT GTTGGATATG TAGGTCGTTT CCTTTCTCTC _Tχχχχ χχχχ TTTTTGGCTA CTACTTAATA GTTTCTCTGT ATAGAATGTG GTATTTTGAA AGTGTATCAA GCTTTAGATT GGTAGTATTC TTGCATTTAA TAAAGGGCAG TGGCCTTTGT TGACTGACAT GACAATATTT TTATAAAATT TGTTATTTGC TTTACAGAAA TTTTGAAAAT TATTGTAGAA ATGTTTTTAC CTCATATGAA CCACCTGACA TTGGAACAGA CTTTCTTTTC ACAAGTGTTA CCAAAGGTAT AATACTATTA CCTGAAAATA CATGTTATAA GGAATCTAGC CTCAGTCTTA GATGATTTAT TATTAATTAT GGCTCTCTTT TTCTAATATA TCAAATATAT TCAAAATAAA AATAAGGAGT AAGTAGATCT CATGTGAGAC TATAATGGTG TTAGTGTGAT CATTAGGCAG TTAAAAACTG TTACAGGCTG

GGCACGGTGG CTCATGCCTG TAATCCCAGC TCTCTGAGAG GCTGAGGTGG GCAGATCATC TGAGGTCAGG AGTTCGAGAC CACCCATGGT CAACATGATG AAACCTCGTC TCTACTAAAA GTACAAAAAA TTAGCTGGAC ATGGTGGCAG GTGCCTGTAA TCCCAGCTAC TTGGGAGACT GAGACAGGAG AATTGCTTGA GCCTGGGAGG CGGAGGTTGC ATTGAGTCAA GATCGTGCCA TTGCACTCCA GCCTGGGCAA TAAGAGCGAT GCTCCGTCTC AAAAAAAAAA AAAAAAAAAA AAGAACTTAT ATTTTCAGAT TGTGTGGTTC CTTTACTAAC TGAATTTAAA TTATTTGTAG TCAATTTTAA ATGCTCTTGT ATTTTAAAGC CACTGTACTC CAGCCTGGGT GACAGAGTGA AACCCTTAAT TCAAAAAAAA AAAAAAAAAA AAGAAAAGCT GGAATATTGG CAAAATCAAG TAACTAAGAG AAAACATTAA ATTCACAGAA TACATTATTA CATTTTAGAT ATATATGGTA TATGTTTTCT

CTGAAAAGCA CAAGCATACC TTTTTTGTTT TAAATGGAGG GAACTAAAGA TACTTTGGTG CCAAAATGAA ACATTATTTG TAATTAATCT CTTATTGAAA TGGGTTTCTA ACTTTAGCTT TGAATCGTAA TCTTTCAAAT TTCTTGTACT CATAGTCACT TGATGATTCT CTATCTGAAA TATTTCTTAG AATTTGTTCT TGACCACCAG AAAAAGATTC AACTGTTACA TAGATGAAAA TGGATGTTGA GTGTTAACAG GCCTATGGGA AACAGTATTT TCTTTAGCTA CATTGTATTG TTGACTGTGT TGCTATTCTT ATAATGTTTA OGTCATTTAA ATTGTTAGAA AGATCCAAGT ATTAAGATCT AGGGTGGCTA ACTTTTCACA GACAAAAAGC TTGTTTGTAA GGTCATTTAC TATACCCTTA ATTCAGGAAG GTTAGCTTGA ATTGGGTCAA AAGGAAACTG GTTAGAAAAT AAGTGAGTAG TGAATAGGCG ATTCAGTGCA AATTCCTTCC AGAAAATACC CTTGTAAATG ACTGTATGAA

TGTGGATTCT TCAAGACAGT CAAATTTATT GTGCGAAAGT AATACTTTTA TTTTTTGCAT CTCTAAAACA TGAACTTTGA GTGATTTTTT AAAAAAATTG ATGCTATTAA ATAGATTCAA ACCATAGAAA TGGAAAATAA ATTTCTGTTT GGGGCTTTTG GGGGGATTAT GTTGTAAAAA TACCTTTTCT CTGTATTTTG TGCTTAATTA GGTACAATTG TTAAGCTAGA TGATAGCCTG TGGATGTTAC TAGTGCAAAA TCAAATTATC GTATTGTGTT TTCTCTGTAA AGTTTTGTCT TGTCTTTTCT AGTGATTTCT CTTATTCCTG TTTATTACTT GATTTGTTTT TACAGACTGT GAAATTATTC GATGACATGA TGTATGAATT AACCAGTCAA GCCAGAGGAC TGTCAAGCCA AAATTTGGAA ATCCAGACCA CTCTAAGGAA TATTTTACAA GTAAGTCAAA TGTATTAGAA AGCAGGAGAG AGAGGGAGCT TAAAGAATGT CAAAATTTTT ATACTGATAC TGATTAGCTA TGTATTCTTA

TGTAATGGCC TAATGTTGGA ATTAAATTTA TAGAATTAAA GACGTGAATA TAGAAACATG AATTCTGAAT AATAAACTCT TATAAGAAGA GAAGTCATCA AGCTAGCTGA CCCTACCTGT ATTTTCAAGG ATATGTGTGG AACACCTGCC ATGTGTTTTG AAGTTTGTGT TAGTATTCTA AATGGCTAGA CAGTTGTTCC AGTATTTGTA GTTCTGATAG ACTAAAGTTC TGTGAAAAGA GGAAGAGACT GTGTTTTGTT CATTGCTGTA TTTGTAGCAC CCAGCATGCT GACTAATACC TTTTCAGTGC ACAAAAAATA TATTCTAAGT GAAATTTCCT TCCTTATTCA CAGACAATGG TGCAGCTCTT AGGAGCTCTC ACAGGATGTG TTCAGCATAT CTGTGCCACA CAGGAATCCA TCATTTTGGA AAATATTCAG AGTCTCCCCT CCTCAGTCCT TCATATAATT AAAAGCACAT TTGTGCATTG TAAGGTGAGT AAAGGTCTAA TTATACTTTG AATGGTATAT AATCAATGTG CATAGGGGCT

GAGTAAAATA ATGTTTGTAT AAGATTTTAC ATTTTAGTCT ATATTATTGA AATAAACTTT TCCATAGAAT AAAGAACATG TAAGTAAATA ATTGTTGCAA AAAAAGTGGT TTTAAGGAAG TCATTAAAAG TGGCTTTTTG GGGTTTTTTA GTTTTATCTT ATTTCCCCTC TATAAAGAAA GAAGTTTTAA GAATTTGTGT TGAGACAGAC ACAGGGATCC TGAAATAGTT ATGTCATGTT GCATTGACCA ATATTCAATT ACCATTATGA TTAGATGTCA GAACTTCCTT TTATAAAGGA AAGTTAATCC TTATTTAGTC CATCTCTACA TGCCAGAGGT AGCCTTGAGG CACAAAAGCT TGCCTAGAAT TTATGGGTCA CAGACAGTTT TAATATTGCT ATTTGTTGGG CGAATGAAAA TCACTAGTTA ATTAATACCT CTCTTTGCTG ATAGGATGCT AAAAATGTCA CGCACCTGGC CTAATGTTAC CCTTTTTTAG TTCTGTATTT GCAAGATCAT GGAAGTCAGA AATAATATTT TATACATGCT

TGCATCTCTT GAAGCACACT ATATTTAATG GATGTTCACT AAACAATGAA TGAATATGTG ATTCAGTAAA TTTATGATCT CTAATAGTAT GAATTAAAGT AAATTTGGCT CTTGAGCTTT GATTTGTTTT TTCTCTCATT TTTATTTATC CGTAATCAGA ATAGTGAATC TGTGTATTCT GGGTGTTTAC ACCTAGTTTC AGACCTTCTC CAGGCTCTTT TCAAGGAGGC CTATTCTCTT CAAAAGCAGT TAATGGAACT GCTGGACATG GTTTGCATGG ACCCTTTAGT AGATGACAAT GATGATATTT TGAATATGGT AATAGGTGAG TGAAGAAAAC TTTCTGCTTA GTATATGGTG ACTATAAATC ATGTATCAAT TAAAATTGTC TCTAATGATT CATGTTATTT TCTTACTAAT TATGCATTAA AATTGATTTA AATCTTACCA AATAAATTTT TAATCTTGAA ATTTGGAATT TGTAAAATTT ATTTTGGGTA CCTTAACCTA GATTTGCGTA TTTAGTTACT GTAATTTCTC CACAATGATT

AACTTATATA ACTTTATAAT CTCTGAGGTT GTCCATATTC AGAGACAATA ACTTTCACAT TTTTTTAACC ATAACTGATA TTGAGATGCA GTTTATATTT CCTTCCAGAA TACATATAAA TACGTGCATA TGTGTATGTA AATATGTCTA TTCTCATATA CATATTATAA TGAAATAACT CATTTTACAT GTGATGCACT TTATACTAGT TTATTTTTAT TTTATTTTAT TTTTTTGAGA CAGAGTCTCA CTGTGTAGCC CAGGCTGGAG TGCAGTGGCA CAATCTCGGC TCACTGCAAC CTCGCCTCCC GGACTCAAGC GATTCTCCTG CCTCAGCCTC ATGAGTAGCT GGGATTATAG GCGTCCGCCA CCACACCTGG CTAATTTTTG TATTTTTAGT AGAGACAGGG TTTCACCGTG TTGGCCAGGC TGGTCTTGAA CTCCTGACCT CAGGTAATCC ACCTGCCTCA GCCTCCCAAA GTGCTGGGAT TACAGGCATG AGCCACCGTG CCCAGCCAAT ACTAGTTTAT TTTTAAAGAA TTGCTGGTCG

TAACACACTT CATTGATTTT ATCACTCATT AATGGATTAT GAACAAGAGT TTGAAAAACA ATATAAAGGC AAAGTTTGCA TTCAAAACTT TGGTATAAAG AGAGTAAGTT GGTTTTGTGC AGTGTATCAG GCACCTGTTG CTCTGCAACA CACCACCTCA AAATCTATTT ATTCACTATT TATTTATTCA TGATTCTGTG AGTCTGCAGT TTAGGGTGGG ATGTCCTGAG ACAACTTTCT CTGATCCACC TGGGGCACTA GCTCACCCAT GTGACTTCAG TGACTTCATT CACATCTGGC TGTTGGCAGA GGCAGAAGTA CTTGAGAAAG CCATGTGCAT CATCCAGCAG GTTCACCCTA TCTCAGATAC CTGATGCCAG TGGTTTCAGG GTTTCTAAGA GTAGCAAAAG TGTGAGCAGG TCGCTGTGTG CTAGCACTTT TCAAGTTTCT GCTTGCCTTA ATTTTATTAT TGTCCCCCGG GCCACAGCAG GTCATAGCGT TTAGCCCAGA GTCATTGTAG AAAAGTGTGG ATTCACAAAG GGCAGTCATT

GTGGCCATTT TTATAAATAA TCTACCACAG ACTGAGTAAA AGCCTTGCAT GAATACCATG GATATTAATT TGAATTCTTC CTTTTTAGAT TTTCTTTCCT TAGCAATTTG TTTTGTCATT TTGGATTAGA ATTATATCTG TAGAATATTT CAGTTATAAT AGGGTACAAC TTTTATTCCA CTGAACATCT TTAGTTTTAT TTAGGTCATC TGGTAGGTAT AAACTTCAGA AGTTAATATT CAATATTTAT AAAAACCATT AACAAGTGTG ACACTTAAAT AGTTTAAATA ATTCTTTTGA CACAACTGTT TCCAAGTTGT GTTACGTATT TTAATTCAAT CAAATGTTGA AATTGTTCAG TAGATAGTTT TAATTATAGG AGAAACTCAC CCCCATGACA TTTGGATGTC TTAAAAGTTC TGTTATCTTT CTTTGCAGTT ATTCATTCTT TATTGGATAT CTGCTCTGTT ATTTCCAGTA TGGACCATGC ATTTCATGCC AATACTTGGA AGTTTATAAT TAAGTAAGTT TGTTTGTTAT TTTTTACTTT

TTAGAAAATG TTTTCCATAT TCCCCAATCT TAATTATTCA TGATTCTTTA GATTGCATTT AAAACATTTT GTGTGAATTT AATGTTCACT GACACTGCTG TCTGATAATC CAGATATTCT ACATGTAGCT CTCAAGCCAA ATTGGACTTC TTTACCCTGT GGCCTCTAAA ATTAAAAAAA ATGTTCTTCC TAGTTAGCTA GTACTTCAGA AATAATGGGC CATGGGCCAG ACTAGAACTT AACCACTTTT CTTCTGCTAC TGTTGTTTAA CCAGCTATCA AGTATCCTAT TTCTAGGATT AGATAAATTG ATAACTATAA TTAAAACTGA ATATAATCTT TTCATTAGGT ACTTTTAAGT TGTTCACACT TAATTCCATT TGTACAGTAA TTTTAACTTT CTGAAACTGA AGCATTTTAA AGGGTCACCA GGGATAGTGC CTGTAGCATT CATCAGATTC TTAGGGGTGA GAGGAGATGT GGTTGAGATG TAAAAATGGT TAAGAATATC TACTTTATAC ACATACATAA AACATTAAAG GTCAGTGTAT TTTCAGGTCT TAGGTACTTT TCTTGTACTA CCAGGACATT AAGTTGCCAT TCAGTGGTTA AGAGTGTTGC CTGGGAGCTG TATCACATGT GCTTAAATCC ATTCTTGAAA TCATTTACTC CTTCTGAGCC CTTGGGCTAT TTGGTTAATT TCTCTGAACG TTAGTTTGCT CATCTGAAAA TGGAAATAAT AATAGCAACT TCTTGACAGG GTTATAGTGA GAATTGAGTT CATCACTGTG AAATGCTTAG AAATGTGCAT GACACATAGT TAATACTCAA GGAATTAGCC ACATCACTAT CATCATCACT GATTATCTTC CACTCTTACC CTCTTCCAGT TCATTTTCTG CCCAGCAGAA TGATCTTTTA AAAAGTAAAT CAGATCATGT TACTCTATTG CTTGAAGTCT ATCCCATTTG ATTAAGAATA ACAACCTAAT

CCTCTGTGGA TGCTGCCTCC TTCACCAGCC TGTCTCATGC TGCTCTCCCT ACTCTTAGTT CCTCAAACAT ACCAAACTCT CCTGTCCCAG AGTCTTTTCG TGGTTTTTCC ATCTGCCTAG GATGCTTCTC TCTCCTATTT TGTGTACCTT GCTAACTCCT GCTTACTGTC TTTCAGTTCT CAGCTTAAGA GTTATATCTT CATGATAACA TTCTTTGATA TCCTTACCCT AAGATTAAGT TAGATTGATA TCCTTACCCT AAGAATAAGT TAGATTAGGT CTCTCTATTG TAGCACCTTA GACTCTGTCA TTTGACAAAT CACAGCCCTA ATTAATTATT CTTAAAATTA TTTAACATTC TCTCTCATGC TAGACCACAA GTTTCATGCA GGTAAGGCGG AGATTGTGTC CATTTGTTTG ACCCCTTTGT CTCCAGGGCC TGGTAGAATG CCTCATACAT AGTAAGAATT CAATTAATAT TTTACACAGA GAAAAAATTA GCAACTTATT TAAACAAATA TAACTGCTTC AGAGGTAAAC TGGGCACATC

TTAGTTATAT TATGTGATAT ATGATGCTTT TTGATTGTTT TTTTAAATGT TCTACAAGGT AGATATTGTT AGAGGTCCTA AGTTACTTGA TGTGTTACTT GTGGTGATTG TATTCTTTTC TTTTTATTCA TTTAGGCAGA GCCTTAAGCA CCAGTCCATA ATAAAAAGCC AGTTGAAACA CAAAGATATA ATTACTAGCT TGTGTGAAGA CATTCTTTTC TCCTTCCATT CTTGTTTACA GTTAGCTGAG CAGATGACAC AGTCAGATGC ACAGGTAAAA TTTGGGCTAA TAGCATTTTA AACAGCAACT CTTATTTTCT TTGGCAGTTA GTAAATCTCA TTTGAATGTC TGGGTCAGTC TATTTAAGAG GATTTTAATT TATTTCATTT GGGTGTTTTT TTTTGATCTG TGGGATTATT TATATCCCAT AATTACTTTT CACCCAGAGC ATTGTATTAG ATTCCTAACT GCTGTCATTG CCTCTGGGGT CTGCCTGGCT CCCTCTTTGC TTGGTAACTG GTTGGTCACA GCATTCTTCT CAGAATCCTT

TCATTCTTTT CTGCATGAGA ACAAAAATTC TTTTGTTCAT ATTTGTATAA GATCTGATAT AGCTGCAATC AATCTTGCAT TTTTTCTTCA CCAACGCATT GCGACCTTTA GGGATACAAG TATGTTTGTG CATGTATATG TATGTATCAG TCTTTTAAAT TTGATATAGT CATACATTTG TTTTTATTTT GAAAAGTTAG AGTGTTGAAT TGGTATCCCA TTTATGAAAC ATTATATTCT AAAAATTTGT AGTACGATTA TTGGGAATTA TAACTCATTT TCCTGTAACA CTGTTATACA TAGTACCTTT TGCTTTCAGA CTAGCCCTCA ATTTTATTTA ACTATAGTAG TCCTAAATTA TAAGATTAAT AGTACTCAGG ACCTAACAGT TATATGTCAT TTGTTTTTTT TTTTTTTGAG ATGGCGTCTC ACTCTGTCAC CCAAGCTGGA GTGCAGTGGT ATGACCTTGG CTCACTGCAG CCTCTGCCTC ACGGGTTCAA GGGATCGTTC TGCCTTAGCC TCCTGAGTAG CTGGGATTAT AGGCGCCTGC

CACCACGCCT GGCTAATTTT TTTAGTAGAG ACGGGGTTTC GCCATGTTGG CCAGGCTGGT CTCGAACTCC TGACCTCAGG TGGTCCACCC GCCTTGGCCT CCCAAAGTGC TGGGATTACA GGTGTGAGCC ACCGCGCCCA GCCTATATGT AATAATTTTA ATGGGACCAT GAATTGAATA TTTCTTCCTT GAATAGCAAT GACATAGCCC CTTCTATTGT ACATCTGCAA GCTGATACAG GGAATTCCTT TGTACCTGCG CTCTTCCCTG CCAGTCAGCT ATGGGGGTGA AAGTGTAGGG GTTCATCCAA GTCCTAAAAC TGGTAGCAAC TCCTAGGGCA GGGCTGATCT GGAAGGACAG ACCCTAGGGG AGGGTGGAAC TTTAAAAAGA AGTTCTGAAG GTAGTAAGAA GGAAATGAGG AGTAGTGTTA GGAAGGGGCT AACTTTTTTC TTCTTGCTTC TCTTCTTTAT CTCACCTGCC CCTCCCCTTG TATCCCTTCT TCCTTTTTCC CTTTCCTTTT TTGTCCTCAC TTCATTCGTG

CATCCTTTCT GATTCCTCTT ACCTTGCTAA AAGGAGAAGT TTGTTTGGGT ATCCTATATC AATGGCAGGA AGGTTGTTTT CTTCTTTACC TTTATCCTAT AGATTCATAT TCTCAACACC AACCTCCTCC TTTTTCAGTT TCCTTCTTGC TTCTCTTGAC ACCACAGAGT TTGCAGCTAG TACTTGGAGA GGAAAATTAA ACAGAGATAC TTGGACCAAG AGTAAGATGA AGAAAGTCTA AACAACAGTA TAGTCTATAG TGGCAAGAGA GAGTATGGGG GCTGCTTAGC CAGGGTGGCT GTACATAAAG TATATCTTCA GTTTATATAA ACTGCTTATA GATGGAAATC AGAAAATTTA AATTCTCTTA ACTGTCCAAG AAAATTCTCA TTTTTTCAAA TTTGGGACTG ATAAATGTGA CCAGTTCTGC TTACTGTCCA TTGCCTGAAA TGGAGCTTTG AGGTGGACTG TATAATTTCT TCAATCTTAA CTCCAAATTC TGATCAGCGA CGCCCTCTGC TGTTCACTAT TAATATTTAT TTACCAATCA

AAGTAAAGTA TTGAAGTTTT CCTGGCAGTT TTCACTTTGT GTTTTAGTCC ATTTAGGCTG CTATAACAAA ATCCCTTAAA CTGGGTAAGG GATTATAAAT ATTAGAAATT TATCTCTCAC AGTTCTGGAA GCTGGGAAGC CCAATATCAA GGCACCAGTA GATTTGGTGT CTAACGAGGG TGTGCCGTCT GCTTCAAAAA TGGCCCCTTG TTGCTGCATC CTCACTTAGT GCAAGGGGCA AGACAGCTCC CTTCAACCTC TTTTATAAGG GCACTTATGT CATTCATGAG GGCAGAGCCC TCATGACTTA ATCACTTCCC CAAAGGCCCC ACCTCTTAAT AGTATCACAT TGGGTGTTAG GTGTCTGGGA GGACACCAAT CTTCAAGCCA TATCATCTCA CTTGGAAAAA AGTCAAAATA AAACCAGTAG ATTTAATTAA TATTACACTA TTTATAGAAG CATGTGATGT ATCATTCCTT GTATTAATTT CCTGGGGTTG CCGTAACAAG TTACCACAAA CTAGGTGGCT TAAAACAATA GAATTTTATT

CTCTCACATT TCTAGAGGCA GAAGTTCACA GTGTGTCAAT AGGGCCATGT TCTCTGGAAG GCTTTAGGGG AGAATATATT TCATATCTTT CTCTTAGCTT CTCGGTGTCA CTGGCAATCC TTAGCTTACT TTGGCTTTCT GTGTCTTCAC ATCATCTTTT TATAAGAACA CCAGTGATAG TGATTAAGGG CATACCTTAC TTTAATATGA CCTCATCTTA ACTAATTATG TCTTCAATAA CCCTATTTCC AAATAAGGCC ACATTCTGAA GTATTGGGAG TTAGAACTTA AAGCTTTTTG GGAGGGACAC AGTTCAACCC ATAACAACCC CTAAAATCGA TATTTATTCT CAATTAAGTC TTGAAATTGG TTTCAAAAAG AGAATATTCT ATTAGAGTTT TTAATGTATA GTTTTAACAT ATAGTTCTTT AGCCCCCAAT TTTTTTTTTT TTTTTTTTTT _Tχ_Tχ_Tχχχ_ττ xxxxxGAGAC GGAGTCTCGC TCTGTCGCCC AGGCCGGACT GCGGACTGCA GTGGCGCAAT CTCGGCTCAC TGCAAGCTCC

GCTTCCCGGG TTCACGCCAT TCCCCTGCCT CAGCCTCCCG AGTAGCTGGG ACTACAGGCG CCTGCCACCG CGCCCGGCTA ATTTTTTTGT ATTTTTAGTA GAGACGGGGT TTCACCTTGT TAGCCAGGAT GGTCTCGATC TCCTGACCTC ATGATCCACC CGCCTCGGCC TCCCAAAGTG CTGGGATTAC AGGCGTGAGC CACCGCGCCC GGCCTGCCCC CAATTATTTA GTTTTTCTAT AAACAGGGAA ATTTATTTGT GTGGCCCTTA GAACTAATTT AATTTCCACT CTAATTCCTA CTTATGTTTA TATAATGCTT TTAGAAATTT GTATTATTCA GAAAATAAAC ATATACTATT GTATCTGTTG CCTACACTTA GATTTTATTG CCTGCTATAT TTAAATTTTA TTAGTATTTT AATTGTTTTA TTAAAGAAAG AATGTGCCTG TAATCTCAGC ACTTTTGAGA GGCCAAGGCA GAAGGATTGC TTGAGCCCAG GAGTTTGAGA CCAGACTGAG CAACACAGGG AGACCCCCAT CTCTACAAAA

AATAAAAAAA TTCTCCAGGC CTCATGGCAC ATACCTGTAG TTCTAGTTAC TTGGGAGACT GGGGTGGGAG GATGCATTGA GCCCAGGAGA TTGAGGCTGC AGTGAGCCAT GATCAGGCCA CTGTACTCCA GCTTGGACAA CAGAGTGAGA GCTTGTCTAG ATAGATAGAT AGATAGATAA TCTAAATAGA TAATAGACAG ATTATCTAAA TAGATAATAG ACAGATTATC TAAATAGATA ATAGACAGAT TATCTAAATA GATAATAGAC AGATTATCTA AATAGATAAT AGACAGATTA TCTAAATAGA TAATAGACAG ATTATCTATC TAAATAGATA ATAGATTATC TAAATAGATA ATAGATAGAT AGATTAGATA GATAGATAGA TAGATAGAGC TTGGACAACA GAGTGAGAGC CTGTCTAGAT AGATAGAAAC AAAGAAAGAA AGAAAGAATG GTGCTCATAT TTTAAAGCAT TGAAAAATGG TCTTCCTTGC TTATATTACC CACACCTTCT TTGTTGGCAT TAAGATGCAA ACTTTGTTTT

AAACAGTTGA GTAAATCAAA GATGGGACTG TTAAGTTATT TGTGTTATTT ACCTGCTTTT TGAAAATGTA AAAATAAAAC TCTAGGTTTA ATTAGTAGTA TGCTATTTAG TAATGAAGTA AAGCTAGAGG CTTCGAACAA ATCTTGTGTA ATTTCCTCTT GAATGAGAGA GAAAATTTAA AGTAAGCAAA CAAATAAGTT GTGTGTCACC ACTCATTCAG TCATTTAACA AGTATTTCCA GAGTACTTAT TCTGTGCCAG GAAATGTTGT AGGTGCCCTC AACAACTTAG AGTCTAGCCT GAGACACAAG TAAGTAGGTA ATTATTATAG AATGGTATGA TCTTTGGAGG ACTGGGTATT GGCTGGCTCA TGGGAGTACA AGATAGGTAC CCAGTGATGA AGTCAGGAAA GGTTTCTTAT GGTGATATGA TGACGTCTAT GCTGATTATA AGGTCAGTGT AGAATAAACT TTGTGCTTTT AAATTTGCAT AGCACTGTAT TAGAGAGTTC ATCTTCAAAA TAATCGAAAA GGCTGAGTGT GGTGACCCAT

GGCTGTAATC CCAGCACTTT GGGAGGCCGA GGTGGGCAGA TTGCTTGAGC TAGGAGTTCG AGACCAGGCT GGCCAACATG GTGAAACCCC GTCTCTACTA AAAATACAAA AATTAGCCAG GAGTGATGGT GCGCACCTGT AATGCCAGCT ACTTGGGAGG CTGAGGCAGG AGGATCACTT GAACCCAGGA GGTGGAGGTT GAAGTAAGCC GAGGTCATGC CACTGCACTC CAGCCTGGGC AACAGAGTGA GACTCCATCT CAAAAAAAAA AAAAATGATC AAAGAAAGGT GAATTTTCAT CTACCCTATT TCTGCTGAGG AAAATGGACT ATTTTCAAAT ATTTTTAATA AGGGTCAAAA TGAGGGATC GCCACCATGG AAACCCTTTG CCTCAGGGCA TCCTTTTGGC TGGCACTGGT TGGATGTGTA ATCAGTGATA ATCCTGAGAG ATACAGCACA AATCTAAGCA ATCATGTGGA TGATTTCACC ACTTTTCGTG GCACAGAGCT CAGCTTCCTG GTTACCACTC ATCAACCCAC

TAATTTGGTC CTACCCAGCA ATGGCTCAAT GCACAACTAT TGCCCACAGC AGACTAAAAT TACTTCAGCT TTCAAATACA TTAACACTGT GATATCTTGT ACTATTTTCA TCGTGGGAAT GGTGGGGAAT GCAACTCTGC TCAGGATCAT TTACCAGAAC AAATGTATGA GGAATGGCCC CAACGCGCTG ATAGCCAGTC TTGCCCTTGG AGACCTTATC TATGTGGTCA TTGATCTCCC TATCAATGTA TTTAAGCTGC TGGCTGGGCG CTGGCCTTTT GATCACAATG ACTTTGGCGT ATTTCTTTGC AAGCTGTTCC CCTTTTTGCA GAAGTCCTCG GTGGGGATCA CCGTCCTCAA CCTCTGCGCT CTTAGTGTTG ACAGGTACAG AGCAGTTGCC TCCTGGAGTC GTGTTCAGGG AATTGGGATT CCTTTGGTAA CTGCCATTGA AATTGCCTCC ATCTGGATCC TGTCCTTTAT CCTGGCCATT CCTGAAGCGA TTGGCTTCGT CATGGTACCC TTTGAATATA GGGGTGGACA GCATAAAACC

TGTATGCTCA ATGCCACATC AAAATTCATG GAGTTCTACC AAGATGTAAA GGACTGGTGG CTCTTCGGGT TCTATTTCTG TATGCCCTTG GTGTGCACTG CGATCTTCTA CACCCTCATG ACTGGTGAGA TGTTGAACAG AAGGAATGGC AGCTTGAGAA TTGCCCTCAG TGAACATCTT AAGCAGCGTC GAGAAGTGGC AAAAACAGTT TTCTGCTTGG TTGTAATTTT TGCTCTTTGC TGGTTCCCTC TTCATTTAAG CCGTATATTG AAGAAAACTG TGTATAACGA GATGGACAAG AACCGATGTG AATTACTTAG TTTCTTACTG CTCATGGATT ACATCGGTAT TAACTTGGCA ACCATGAATT CATGTATAAA CCCCATAGCT CTGTATTTTG TGAGCAAGAA ATTTAAAAAT TGTTTCCAGT CATGCCTCTG CTGCTGCTGT TACCAGTCCA AAAGTCTGAT GACCTCGGTC CCCATGAACG GAACAAGCAT CCAGTGGAAG AACCACGATC AAAACAACCA CAACACAGAC CGGAGCAGCC

ATAAGGACAG CATGAACTGA CCACCCTTAG AAGCACTCCT-3' (FRAG NO 1738) (SEQ ID NO 12378)

5'-GCCACCATGG AAACCCTTTG CCTCAGGGCA TCCTTTTGGC TGGCACTGGT TGGATGTGTA ATCAGTGATA ATCCTGAGAG ATACAGCACA AATCTAAGCA ATCATGTGGA TGATTTCACC ACTTTTCGTG GCACAGAGCT CAGCTTCCTG GTTACCACTC ATCAACCCAC TAATTTGGTC CTACCCAGCA ATGGCTCAAT GCACAACTAT TGCCCACAGC AGACTAAAAT TACTTCAGCT TTCAAATACA TTAACACTGT GATATCTTGT ACTATTTTCA TCGTGGGAAT GGTGGGGAAT GCAACTCTGC TCAGGATCAT TTACCAGAAC AAATGTATGA GGAATGGCCC CAACGCGCTG ATAGCCAGTC TTGCCCTTGG AGACCTTATC TATGTGGTCA TTGATCTCCC TATCAATGTA TTTAAGCTGC

TGGCTGGGCG CTGGCCTTTT GATCACAATG ACTTTGGCGT ATTTCTTTGC AAGCTGTTCC CCTTTTTGCA GAAGTCCTCG GTGGGGATCA CCGTCCTCAA CCTCTGCGCT CTTAGTGTTG ACAGGTACAG AGCAGTTGCC TCCTGGAGTC GTGTTCAGGG AATTGGGATT CCTTTGGTAA CTGCCATTGA AATTGCCTCC ATCTGGATCC TGTCCTTTAT CCTGGCCATT CCTGAAGCGA TTGGCTTCGT CATGGTACCC TTTGAATATA GGGGTGGACA GCATAAAACC TGTATGCTCA ATGCCACATC AAAATTCATG GAGTTCTACC AAGATGTAAA GGACTGGTGG CTCTTCGGGT TCTATTTCTG TATGCCCTTG GTGTGCACTG CGATCTTCTA CACCCTCATG ACTGGTGAGA TGTTGAACAG AAGGAATGGC AGCTTGAGAA TTGCCCTCAG TGAACATCTT AAGCAGCGTC GAGAAGTGGC AAAAACAGTT TTCTGCTTGG TTGTAATTTT TGCTCTTTGC TGGTTCCCTC TTCATTTAAG

CCGTATATTG AAGAAAACTG TGTATAACGA GATGGACAAG AACCGATGTG AATTACTTAG TTTCTTACTG CTCATGGATT ACATCGGTAT TAACTTGGCA ACCATGAATT CATGTATAAA CCCCATAGCT CTGTATTTTG TGAGCAAGAA ATTTAAAAAT TGTTTCCAGT CATGCCTCTG CTGCTGCTGT TACCAGTCCA AAAGTCTGAT GACCTCGGTC CCCATGAACG GAACAAGCAT CCAGTGGAAG AACCACGATC AAAACAACCA CAACACAGAC CGGAGCAGCC ATAAGGACAG CATGAACTGA CCACCCTTAG AAGCACTCCT-3'(FRAGNO JfSEQ ID NO 11850) 5'-GATCAAAATT TTTACCTATT ATGCATTTGA TATATAAATA AGTATATAAA TGCACACACA GACACAGCAA TGATGGTGAA CAGTCTTCAT ACAATTATAT GGATGAATCT

CATAAAATGC TGAGTTAAAG AAATCAGACC AAAGAACATA TACTGAAAGA TTCTCTCTAT ATACAAAGTT CAAAAATAGG TGGACCAATT CATGGTGGTG TTAGAAATCA GAAGAGAGGC TACCTTTGTG GGGAGGGGAC AGTTTAATGC CCAGAAGCGG TAAATAAGGA ATCCTCTGGG GAGTGGTAAT GATCTGGATG CTGGCTACAG GATGTGTTGG TTGTAAAAAT GCATTTTTTT ATATCTAGCT TTTTCCATGT GTATATTATA CTTCAAAGAA GTTCAGTTAA TAATTTCTCA TGTCACTGTA GAGTAGCTCA GTTAGCCCCA GCAAGCCTCT GGCTTAATCT TGTTTTACCT TAAGCCATCA GTCATTT ACA AGTAGGAAAA TTCACAGGGA AAGTTAGAGT ATAAAATCCA GAATGAAGGT TTACTGGGTA AGAGTCTCTC CATTTTCCAA AGCCCGTTTA TTTCTTGATT CCAGTTCTTA AGAAGTCTCA GCATTGTGTC TTTTTCATGT ATCTTACAAG AAGACAGCAT

GTGCTTCTAA CACCTGATAC ATTGTATCTA CCAGCACTTG GTAAACAGAA AAGAACCACA TTTTTCTTGT AGGAGAAATT TGGTGCCTAT TTCCTACCAG GCACCAATAA GTGGGACCAA TAGGTGGGAT TAAAGATACA GTAGAAAGTA TTTAAAACTT GCCAGGGGGC AATAGTCTGA AAATAAGTAA ATTGGTGCTA TAGAATGGAA GTTACAGGCT TCTTTCTTTT TTCCCACAAG ATCTGCTCCT TGAGCCCCTA GAGACTTTTC TGTCTGTTAC TGTTTCTTCA TTCCTCATCT GCAGAGCCAG CCCTGAGAAG TGCAGACCAA AGCCAGGGAA GGCTCTGCAA AGATGTACAA ATGGAAGTCA CCTTAATAAC CTCTGACTGC TGCGCATAAT ACATTTCACT CAAAAGAGGG GTTAAACAAT GGAACAGAAT ACAGAGGCCA GAAATAATGC TGAACACTGA CAACCATCTG ATCTTTGACA AAATCCACAA AAACAAGCAA TGGAGAAAGG ACTCCCTATT CCATAATGGT GCTGGGATAA

CTGTCTAGCT ATATACAGAA GATTGAACCT GGGCCCCTTC CTTACATCAT ATACAAAAAA TAACTCAAGA TGGAGTAAAG ACTTAAATCT AAAACCAAAC ACTATAAAAA CCCTGGAAGA TAGCCTGGGA AATACCATTC TGGACATAGG ACCTGGCAAA GACTTCATGA CAAGACACCA AAAGCAATAG CAACAAAAAC CAAATTGACT AATGAAACTA ATGAAACTCT TTAGTTGTAC AACAGATAGT TTATCTGTAC AACAAAATAA ACTATCAACA GAGTAAACAA CCTACAGAAT GGAAAAATTT TTTGCAAACT ATGCATCTGA CAAAGGTCTA ATATCCAGAA TCTATAAGGA ATTTAAACAA ATTTACAAGC AAAAAAATGA CCTCATTAAA AAGTGGGCAA AGGACATGAA CAGATGCTTT TCAAAATAAG ACATTCACAC ATCCAACAAC CATATGAAAA GATGTTTAAC ATCACTAATC ATTAGAGGAA TACAAATCAA AAGCATAATA AGATACCATC TAATACCAGT AGGAATGACT ACTATTAAAA AGTCAGACAA TAACAGATGC TGGTGAAGGT TGTGGAGAAA AGGGAATGTT TATGCACTGC TAGTGGGAAT GTAAACTAGT TCAGCCATTG TGGAAGAGAG TGTGGTGATT CCTCAAAGAA TGTAAAACCG AACTGCCTTT CAATCCAGCA ATCCCATTAT TGGATATACA CCAAAAGGAA TAGAAATTGT TTTACCGTAA AGGCGCATGC ATGCATATGT TCATTACAGC ACTATTTACG ATAGCAAAGA CATGGAATCG TCTAAATGCC CATCAGTGGT AGACTAGCTA AAAAAAAAAA AATGTGGTAC ATATACATCA CAGAATAGTA TGCAGCCATA AAAATGAACA AGATCATCAT GTCCTTTGCA GCAACATGGA TGTAGTTGGA GGCCATTATC CTAAGCAAAT TAATGCAGGA ACAGAAAGCC

AAATACCACA TGTTCTCATT TATAAGTGAC AGCTAAATAT TGAGTACACA TGGACACAAA GAAGGGAACA ATAGACATGG GACCTACTTG AGAATAGAGG GTGGGAGGAG GGTGAGGATC AAAAAGTACC CATAGGACAC TGTGCTTATT ACCTGGGTGA TGAAATAATT TGCACACCAA ACCCCTGTGA CACACAATTT ACCTATATAG AAAACCTGTG CATGTACCCC TGAACCTAAA AGTTAATGGT GGGGGGGTGG GGTTAAGCTA CTTTGTGGTA TAAATCTGAG CATTCATATT AAAATAAAAT ATTTACCTCA TTAGAGTAAT TAACATTTAT TAAGCAAAGA GCCAAGTACC TTACACACAT GATGTTTAAT CTCACAATGA TCTTTAATCT GATAACAACC GTCCATTGTA TGTACATATG TGGAAATTGA GCCTTGGAGA GATTAAATGC ATGGGGCATG CCATTTGACT AGAAACTGGA AGCATCAGGA TTTAAACTCA GTTCTGAATG GTTTTGTAGG CTTTGTTTTT

TCCACATTAT AGCATGGCCT GCCATGAAGA ACAGGTCCTT TCTGGTGTTT GTCTTGTTTG GTTTAAGTGA AGCAAATATT TATTTAAATA TTCAAGATAT GCTGTTAAAT TTTTACTCAA AAATTTGAGT ACAGTATGGA TCTTCTGAAG CCAAATAACT CTTATTCAAT GCTTAGTTGA GAAATTTTAT GGAGTAGTTC TCAATTTTTA TGTAGTTCCA CTGCAAAGGT AAGTCTTATG GAAAGATTCA CTGTAATTTT TTTTCCTCAT TTGGACATCA GCTTTTTCTT TTCCTCAGAC CCGCTGAAAG ATAATTTTTA AAATAAAAAC CTTGTTTTTA TATCAAGTGG GGACATTTTT TCCAAATGAA AACCGTGTAT TCATTTTATA TGATAAAATC AATGTTATTA TTTTTAAAAT TTTGATTTAA AAATCATTAA AAATAAATTT TCAGATATTA CCTGAAATTC TACCATCCAG AGATAATAGT GCTTAAAGAT TTGATATATA GACACACACA CATATATACA TATATATCAT CCTAAACTTC

TTTGTATAAA TGTATATAAA GTTTTTAATA AAAACTAGGA GATTAATGCC CTTTGAATGA AAATAAATAC AATGTGTATG CTTTAACATC TTGCCTTTAC TTTATAACAT TTATCACAGC AGTCATGAGA TAATGATTTA CATGGTCATT GTTAGTAAGC TAATAGCTAA GTGCATGAAC TCTGGAGCTA GCCTCCCTGG ATTTTAATCC CAGATCTGTC ACTGACCAGC TGAGCAATAC TAGGTAAATT GCTCTTGTTC CTTAGTTTCT TCATCTGTAA AATAGAGATA AAAATAATAT CCACCTCATA GGATTGGTGT GAGCATTAAA TGAGCATACG TATGTAGGCC ACTTAACAAC AATGCCTTCA CATACTGAAC ACAAATATAC GAGCTGTTGT CTTATTGGGC TCATGTTTTT CCTACCACTA AGCCGCATGC ATGCAAGGAC CATGTTGGTT TTGTTCCACA TTGCATCCCC AACCTGGTAT ACAGTGTGCA TTCAATAGTT GTTGACTATT ATTACTAGTG GCATTTAACA AATATCTGTT

AAATGAGTGA AGAAATACCC ATTTACTGCA AGTGTGTCTA ATATTGATGG CATAATGGGG GAAACTCAAA CTCTGGAGTC AAACAGGTTT TAAAACCTTA TTCCCTCATC CTCAGTTATT GACGTTTTTT TTTTGGCAGG TGTGTGTGTG GGACAACTTA TTGAACTTTT CTGAATTTCC AGCTTCGCAT ATATAAAATA GAGATAGTGA TTCATTCTTG CAATGTATGG ATTTGAGACA ATTGTGTAAG TTTATCAATA AATAGTAGCT ATTTTTGTAT AAGTATTACA TATAATATCC AGGCCACTGC TTTGCATAAC CCAAAAGGGG CACCATTCAT GCAGAATACA ACATAAATGG TGTCCCTGGA GCAGTGCAGT ATAGGAACCC TGAGGGGACC TACAGTATAC TTTATAGTTC ATAGATTACA AATTATCCCT TTATCAGAGT CTCTCAAGGT TGGATGTATT TGAGGTCCAT AAGAGCAATT TAGGATTAAC AGTAGCTGCA GAAACCATCT GCAGTGATAT TCTCATTTTA AATCCGCGGG

AAAGAAGACA GCTATAAACT TGGGACCTGG GTTTAAGCAT TTTAAATGCC AAGTTCACCA TTTTCTAAAA CACAACAAAT ACCCAGTGAG AGAGGGAGAA GGGAAGTAAA TGCCTCTGAA TAAGCAAGTT AATGTCAGTA GTTGTACTGT ATGCATATTG ATGAACAATA GAGGAACCAA TGTCCAATCA GATGAGCAGG ATATTTGGCA ATAACAAGTT GCCTTTGAGG AAAAATGATT TTCTTGGCAA GTTCTTTATC AGCATTACAA AGCTAAAAGC TACGCTTATC ATCACTTATA CTAGCATACC CTGTTGTGCA AATGCTGTCT GTGTTTGCAT CTGCTATTGT TGATGCCTGG TGCATGAATC AGGACTCCAG CCCACAAGTT TTCCCAGAAC TTTCTTATGG CCATCATCTT TAAGTGTCTG GTGAACAGTC ATAGTTTGGT ACACAAAAGG GTCAACCTGG GGGATGGCTA GGGTTTGACT CAGTCGTTAC ATTTCAATAG AGCAGGAAGG GGAAATGGTG GCCTGTAACC TCAGGGAATT

TTGCCAGTTG GTCCACCCCA CTCTCTCTCT CCTGCTCTGA GGAAGTGGCA CAGCCTAGAA CAGCACCACA GGTGAGAGAA ATGCAAACCC TAACCAGAGA AGCAGACTCT TTGCCAGTAG TAATAGTTCA GGACCACCAC CAGCTTTTAT TAAAATTTTT AATAACACTC AAGTATTGGC AGAAAGAAAT AATCTTGGGT TAACTATAAC TAGAATATTG ACTCTTCCTC TGTGGAAGAA TCAGCCAATC ACATTTGTTT ACATCAGTTC CCCTGAAGAA GAAAAATACA CTGATGTTGC AGCAAGACAA ATTTAAGCTA GATGTAAATA ACTTCCTTTA GCCTGTAATG CTAGGCTAAT TACATATTGG AACTATTTTT TCAGGGAAGA ATTGTGTAGG GTTTCAGGGA AGAATTCTGA AGAAAATATA GAGCTGAAAT GATCTTGCAG CTCACTGAAA CTGCAGGGTT TAGATCCACA CTGATACTCG TTCTATTATC ACTGTAATGA AGGCTGATGG AATAAGTAAA AATGTTTTGT ATTAGTATGT

TTTTACACTT ATTTGCAAGG CATAAATAGG TTAGGTTTTG ATCTTAATTT AATTCTAACA TGTATTGTGC ACAAGCTGTG AGCAGTTTTC AGGAGTTAGG TATCTGGCCA TGACTGATTT TTCAGGAGTT AATCATCTGG TAGAAGGGTC ATACACAATA GGAAGATGTG TGTGACAGGT TGTGATCATT ACTATAATCA CACAGAGAGC TGTAGAATTT TAGGCTGGCA GGGTGGCTCA CGCCTGTAAT CCCAGCACTT TGGGAGGCCA AGGCAGGCGG ATCAAGAGGT CAGGAGATGG AGACCATCCT GGCTAACACG GTGAAACCCC GTCTGTACTA AAAATACAAA AAAAAAAAAA AGCCAGGCGT GGTGGTGGGC GCCTGTAGTC CCAGCTACTT GGGAGGCTGA GGCAGGAGAA TGGCGTGAAC CCGGGAGGTG GAGCTTGCAG TGAGCCGAGA TCGCATCACT GCAATCCAAC CTGGGCGACA GAGGGAGACT CAGTCTCAAA AAAAAAAAAA

AAAAAAAGTC ATGTTAGATC CAGAGGGGTA GCAACTGGGG CTGGGCTGTC AGTCAACTCA GTCAACTCAG TCAACTCTGC TCCCCCACAG GAGATGCCAG TGATGCATTT TCATGGCCAA CATTGTCAGT CAGCATCATT GAATTACTCC TGATTATAGA GACACAGCTG CAAACGATTC CCCATTAAAT ATGATGTTTC TTGCAATGTT TGGAAGGTAC TCCTTTTTAG TAAGGGAAAT CCCCTCTTCT GGCTTGCTGA AAGTTTTTTC TTTCCATTTT AAAAATCGTG AATTCCTTTT TGCAATATTG AGGTGGTTAT ATGGTTTCTC TTCTCTAATC TGTTAATATG GTGATTTAAT GGTTAGAAAT TTTCTAATGT AAATTCCACT CATATTGCAG AAATAAACCT AAACTGAGCA TGAGGCTATA TTTTTTATTT GCTTCTATAT TTGGTTGCTA TACAGTATTA TGTTTAAGAT TTGTTCACAT ATATTTGTGA ATGGGATTGG ACTATTTTTC CTTCTTGCCG ATTTTTATCT GGTTTTTAAA

TTAAGGATAT TTTAGACTTA TGAAATATTT GGCAAACAAT CCTTGGCAAG TAATTTTTTG GGGAATTTGT TTTGGCTATT TTGAGTATTA CCCAATATAT TTTAATTAAG TTATTCTTAA TGTTTTCTTA ATTAAAAAAA TTACCTACTC TAGAGATATT CTTTATGTAC TCCAGATTTT GTCTATTTAT ACCACTTTTC TTTTTTCCTC GATGAGTGTC ATAGATGTTC ATCTATTTTT TTATCTTCTT TGATCTTCTC TTATTCCTTG TTTCTATTAA CTTCTGAAGT TTATTATTTT CTTTTTTCCA CTTCCTTATG GTTTATTCTT TCAATTTTTC TCTAACTTCT TAAGTTGGGT GTTTAATTTT TAGCTTGCTT TGCTTTTTTA GGATAAGCAT TAAAACTACA AATTTTCCTT GTTATTCTTT TGCTGCACCC CAAATTGTTG ATATTTCTAT TGTCTAATTT CTATTCAATT AGAATACTTT AAAGTTTCTT TTTGGTTTTT AAAAACTAAC TTTTTAAATT GACAAATAAA AATTGTGTAT

ATTTATTGTG CACAGCATAT GGCTTTGAAA TATATGTACA TTGTGGAATG GCTAAATTTA GCTTATTAAT GTATGCATTA TCTCACATAC TTATCATTTT TTGTGGTGAG AGCTATGTGA CTTTTGAACT TATGAGTTAT TTAAATATTT TTAAATTATT AAGCATATTG GGATTTTAAG TAATTTACCT TTTTATTATT AACTTATAAC AAGTAGAACA GTTAACCTGT ATGATTCTAC ATCATTGAAA TTTATTGACA TTTGCTTCAT AGTCTATTAT ATGGTCTACT TTTGTTCATG TTACATCTGT AGTAGAATTG GCTAATAGTT GAGTAAAGTA CACATATGTC TATGAAATCA AGTGTAATCC AGAGAAAAAG AGAAATTTAC TGAATATATT GTTCTAGGTG CTATTATATG TTGTCATGTT TAATCCTCAC CACAATTGTA TGAGGCAGCC ATAATTAATT CCACTTTACA CATGAGGAGC CTGAGGGTTA AAAAAAAAGC TAGCTCTACT ATTTGTAAAG AATGAAGCAA AGATACAAAT

GAAGGCCCAC ATATCCTATA ACTAGATATT TAAGCATTTT AATTCAAGCT TTAAAACTGC TAAATAAAAT GTGCTCCAAT TTCTATATTG ACAGACATAC CTTCCTAATG AGCTGGGGTT CGAATTTAGA AATCTTTGAT GCTTCAGAGT CCACACTGAA ATGTGGAGGC ACATAGTGAG TTGGTCCCCA GCCTTCAGTC CACCCACCTT CTCTTTACTA AATCACCTTT CACATACATG TATGAACACC CCAGCCTCCA AGTCCAAACC CTAAACAAAA TGGGACACCC TTGTGCATAC ACAGAGACAC AGCCCATCCT CAGGAAAACC TGGAAAAGTC CATACAAGTT CTGGAAGCAA GCTTGGGACG GTTTCAGTAG TGTGGTCTAT AAGGGAGGCC TCAGAAGACA GGTTTTCTTA ATTCTGTGAA CTTCTCCCAC AGTAGAAAGG GTGCTGGAGG AGGGTCAGAG TGAGGACTTC TAAAGCATGG GTCCTGAGTA GGGGCCACTC TTGCCCAAGT CTAAGAAGGG TACTAGAATA

GCACACTACT ACTAGATACT AGAACCCAGA TACAAGCACA GGTCTTCTGA AATTAATAAT AATAATAACT ATTACCATTA TTATACCAGT AGCTGTCATT TATTTAGTGC TTATTATTTG CCAGTCACTG TTCTAAATTC TTTACATGTA TTATACAACT GCCATATAAC TGCCATATGA GGGATGTACC CTCATTGTCA CCATTTTACC GATGAGAAAA CTGGCATAAA ACGTTTAAGT AACTTGTCCA AGTTACAGAG CTTAGTGAAG CCACAATGTT GCTCAATTTG CTCTCAAACT TCAAAGGGAT GGGAAGGACA CCTAAGTCAT AGAGTCTTTA AGAATCAGAG CTAGAAGGAA TCTTAGATGT TATCTAGTCA GCCTCCTCCC ATTACAGTCC AAGAGAAGAT GGCCCTGAGT TACTTGTAGC TATTTTTGCA TGTGAATTGC AAGTGAATAT ACATTCTACT GAAGATAAAA GATATTTAAA GATATCGCTG GATATAGGAA CAGTGGTTTT AAATCTCTAG GCTTTAACTT TTCTCAGAAC

AAGAAATCCT TTTTGGTTTT AATCTATATG CACATCTGTA TTTTTCTCAA TTATCGGGTA GTAAAATATA ACTTTTCTTC TGTAATATTT TTTAACTTTA ATGAGTGTTC CTCATAATAG AAAAGTTTGG AAACCATTGC TATGGGTATA TACTTTCTAA AGGGATAGTA ATTTCTCTAG AATATTCATT TAATGCTCCA GAAGTAATTA GCACAATTGT GCAAGTCTGT GCATCATCAA CTATACATTC TGCCTGTTTA CTCCAAATCC ACATGAAACT GATTATACAG TCAAAGGCGA GCCCAGTGGA GAGGCATTTT TGGAGACTTC CTGGTACATT GAGACAGGGT CGGCCAGTCT GCGTTAGGGT CTTGGTCAAA ACTGCATTTC TGAAACTAAA CTCAGATTGC TTTCTTTTAA GGGGTCAGAA CTGATTCAAA TCTACATTTT TAAAAGCCTT AGATGTGGGG CTTTTCCTAT TCCCAGTCTC CGCTATTGGT CTTTGTGAAT CCACAGGCAA TTTGGCCACA TCCTTGACTC TCTCTTATAT

TAAGAATTAA ACAGCTAAGT TCATGCAGAG GAAATATAAC AAAGGAGGGA CTTTCCTACA AGATCTTTGA AAAATGGAAC ATTTGCATAA GTCATATTTA GCCAGAACTG TTGTTTTATA TTTTCCTTTC TGAATACTTT GTTACACCTC CTCCCAGCCA ACCCCCCCCC TCCCTGACCC CAACTAGTCA GAGACCAAAG CCTTCACAAT GGTTTACACT TGAACCTTCC TGGCCCCACC CTCATCATCA CGCCTGAATA ATTACATTCA CTGACTGGTC TCCCCTGCTT CCGTTTATCT CCACTCCTAA ACCCTCTGAC ACCTTAATCT TCCCAGAATA CCATTGTGAT CCTGTTCCAC TCTTGCTCAA GTTTTCCCAG AAACTAGAGT ACAAACTTTA TAAGCTTTAG AGTTGAAAGC CACTCTATCT CTTTTTCATC CCCAGGTCTC TGCCAAGGCA GTATAACCTG TCCAACATCT CTAACTTCAA TACCTTTGTC TTAGATACTA GACTCTCCTC CTGGTTTCTA ATTAAACCTG ATCTAGGATC

TAATTTTGCC TCTGAATTCT GTTGCCCTTT GCCAAGTGAT CTCTTCCTCC TCTGAGCCGC AGCATCTCTG AGCTTGCACA CTTAGCATAG CCATAGCACA CACAGCCTTA GCTTGCAGTT CAGGGTGTTT ACCTTCCCTC CCCTTCCAGA TGCTGGATCC CCAGGGATAG GAACTCTGCC CTTATGTGTC CATAGCCCCT GGTAGTATGT CTTGCAGTCG TACATTTTCA GCAAATGTTT AATTGGTTAA TTGAAGACAA CTGTCCCATG CCTTAAGCCT CTCTTTTTGC TAAACATGCC TGTGTCCTTT GTCATTGAAC AACTATTTTG ATCTATTTTC TTCCTGACAT AGGGGTCAGT TCCGAGGATG CTGAAATCAA GAGACATAGC TTATTCTCTC AAAATTGCTT TCAAGAGTGA TTTTGTTGTG AATTGAGAAC TGGCTGCCTA CTTTTGGACT ACCCACTTCA GCAAGAGTGT TTGAAACCAA ATCTATTCTA AGTAATTTTT TATTCCCTTT TCTCTATGGC ATTAGACACA CAGCTCTTTT

AAACTACCTT TCGTTATCTA TTAAACAGAC ATTCAGTAAC TCTATAGACA CTGTCTAGCT ATATGAACTT AGACAAACTA ATATCTCTGA GCTTCAGTTT CTTAAAATTT AAAATGAGGA CAATACCATC TATGGCCGGG GATTAAATGC TATGAGGAAT GTAAACCAGA TGTCAGGTAC CATCTCTCTA AAATCCAGAT AAAATGAATT AAAAATACTG GCCGCAAACC CTCTCTAAGA GTTCTCAAAA TTCTCAGAGA GCTTAATTTT CATGCTCACC ATAGCACCGA TTTTCTTCTA AATATTTTGT TTCTACCAAA ATATTTTGTC CCAATTTTGC CTTTTATGGC TATTTCTTCA TATCCACTTT CCCAAACTAA AGAAGCAGCC CCTTCACCTT AAACTCCTCC TTCAAAGCAA CCTAAATACA GGTCTGGGTT TGTATTCCTA GTGGGATGTT ACAGAGGTTA GTGTGATGCA GAGGAGGAGT CATGCTGTTT AAATCCATAC TAGTCCCCAG AGGCCAGGCT GCTTCTGCCA CCCCTACCCC

TCCCGCCACA GAGCTCTTCA GCTTCTCACA TTTCTAGTTC TTCTCTCTCT ACTTTCATTA CCTTCTCTCT TTTTTTTTTT CTTCTCATGT GCTCACGGGA GCAGAGAAAA TTAACTCCTC TAAGTTTTCT TAACACAGAG TGCCTTAATT ACATATTACT ATTGTTTGAG TTCCTGCCAA CACTACGTCT GTAGGGTCAC ACCTGCTATA TTAGAGGCTT ATCAAAAAAA GATAGCTTTC TCCTAAAAAG GGATTTGGAT GCCTACTAAG ATAACTGGAT GCCAAGATAA GTTTAACCTA ACAAACTTTA TTATTATTAT TATTATTATT ATTAGAGATA GGTACTTATT GACTGCAGTG CAGGGATGCA ATAATAGCTC ACTGCAGCCT AGTTCATGCA TGAGTAGCTA GGACTACAGG CATATGCTAC TCTGCCCAGC TACTTTTAAA AAAATAATTA GGGATGGGGT CTTGTTGTAT TGCCCAGGCT CGTCTCAAAC TTCTGGTTTC

AAGCAATCCT CCTGCCTTTT ACCTCCCTAA TTGTTGGAGT TACAGGCATG AGCCACAGCA CTCAACCAAG ATTTAAAAAC TTTTAAAAGA AATCACATTA CTTACTGTTA TCATCATTAT GGTTACTACC AGTGTTAAAA CAATTGGTAT TGAAAACACC ACTACCAGAT CAAGCTTCAA ACCAAGATGT CAAGTAAATA TTATTGTCAG ACCTCTGAGC TAACTGATGA

TTCCTGCCCC ACCTTGACTG AGGGATTAAC CTTGTGAAAT TCCTTCCCCT GGCTCAGAAG CTCCCCGACT GAGTACCTTG TGACCCCCAC CCCTGCCCAC AAGTGAAAAA CCCCCTTTGA CTGTAATTTT CCACTACCCA CCCAAATCCT ATAAAACAGC CTCACCCCTA TCTCCCTTCG CTGACTCTCT TTTCAGACTC AACCTGCCTG CACCTAGGTG

ATTCAAAAGC TTTATTGCTC ACACAAAGCC TGTTTGGTGG TCTCTTCACA CAGACCATGT GACATTTGGT GCCGTAACTC AGATCGGGGA ACCTCCCTTG GGAGATCAGT CCCCTGTCAT CCTGCTCTTT GCTCCATGAG AAAGATCCAC CTATGACCTC TGGTCCTCAG ACCAACCAGC CCAAGGAACA TCTCACCAAT TTTAAATTGG GTAAGTGGCC TCTTTTTACT CTCTTCTCCA GCCTCTCTCA CTATCCCTCA ACATCTTTCT CCTTTCAATC TTGGCACCAC GCTTCAATCT CTCCCTTCCC TTAATTTCAG TTCCTTTCTT TTTCTGGTAG AGACAGAGGA AACGTGTTCT ATCTGTGAAC CCAAAACTCC AGCACTGGTC ATGGACTTGG AAAGACAGTC TTCCCTTGAT GTTTAATCAC TGCAGGGATG CCTGCCTGAT TATTCACCCA CATTTCAGAG CTGTCTGATC ACTGCAGGGA CGCCTGCCTG GATCCTTCAC CTTAGTGGCA AGTACCACTT TGCCTGGGTG GCAAGCACCA CCTCTCCTGG GGGGCAAGCA CCACCTCTCC TGGGGGGCAA GTACCCCCCA ACCCCTTCTC TCCATGTCTC CACCCTCTCT TCTCTGGGCT TGCCTCCTTC ACTATGGGCC ACCTTCCACC CTCCATTCCT CCCTTTTCTC CCTTAGCCTG TGTTCTCAAG AACTTAAAAC CTCTTCAACT CACGTCTGAC CTAAAACCTA AATGCCTTAC TTTCTTCTGC AATACCGCTT GACCCCAATA CAAACTCAAC AATGGTTCCA AATAGCCTGA AAACGGCACT TTCAATTTCT CCATCCCACA AGATCTAAAT AATTCTTGTC GTAAAATGGA CAAATGGTCT GAGGTGCCTG ACATCTGGGC ATTCTTTTAC ACGTCGGTCC CTCCCTAGTC TCTGTTCCCA ATGCAACTCA TCCCAAATCC TCCTTCTTTC CCTCCTGCCT

GTCCCCTCAG TCCCAACCCC AAGTGTCGCT GAGTCTTTCC AATCTTCCTT TTCTACTGAC CCATCTGACC TCTCCCCTCT TCCCCAGACT GCTCCTCCTC AGGTCGCTCC CCGCCAGGCT GAATCAGGCT CCAATTCTTC CTCAGCGTCC GCTCCTCCAC CCTATAATCC TTCTATCACC TCCCCTCCTC ACACCTGGTC CAGCTTACAG TTTCATTCTG TGACTAGCCC TCCCCCACCT GCCCAACAAT TTCCTCTTAA AGAGGTGGCT GGAGCTAAAG GCATAGTCAA GGTTAATGCT CCTTTTTCTT TATCCAACCT CTCCCATCTC AGTTAGTATT TAGGCTTTTT TTCATCAAAT ATGAATACCT AGCCCACTCC ATGGCTCATT TGGCAGCAAC TCCTAGACAT TTTACAGCCT TGGACCCAGA GGGGCCAGAA GGTCATCTTA TTCTCAATAT GCATTTTATT ACCCAATCCA CTCCCAACAT TAGAAAAAGC TCCAAAAGTT AGACTCCGGC CCTCAAACCC CACAACAGGA CTTAATTAAC

CTTGCCTTCA AAGCGTACAA TAATAGAGTA GAGGCAGCCA AGTAGCAACA TATTTCTGAG TTGCAATTCC TTGCCTCCAC TGTGAGAGAA ACCCCAGCCA CATCTCCAGT ACACAAGAAC TTCAAAATGC CTAAGCCACA GTGGTCAAGC ATTCCTACAG GACCTCCTCC ATCAGGATCT TGCTTCAAGT GCCAGAAATC TGGCCACTGG GCCAAGGAAT GCCCTCAGCC TGGGATTCCT CCTAAGCCAT GTTCCATCTG TGTGGGACCC CACTGGAAAT CGGACTGTCC AACTTGCCCA GCACCCACTC CCAGAGCCCC TGGAACTCTG GCCCAAGGCT CTCTGACTGA CTCCTTCCCA GATCTTCTTG GCTTAGTGGC TGAAGACTGA TGCTGCCTGA TCGCCTCAGA AGCCTCCTGG ACCATCACAG ATGCTTTTGG TAACTCTTAC AGTGGAGGGT AAGTCCGTCC CCTTCTTAAT CAATGCAGAG GCTACCCACT CCACATTACC TTCTCTTCAA GGTCCTGTTT CCCTTGTCTT CATAAATGTT

GTGGGTATTG ATGGCCAGGC TTCTAAACCC CTTAAAACTC CCCAACTCTG GTGCCGATTT AAACAACATT CTTTTATACA CTTCTTTTTA GTTATCCCCA CCTGCCCAGT TCCCTTATTA GGCTGAGACA TTTTAACCAA ATTATTTGCT TCCCTGACTA TTCCTGGACT ACAGCCACAT CTCATTGCTG CCCTTCTTCC CAACCCAAAA GTGGCAACTC CTTTGCCACT TCCTCTCATA TCCCCCTACC TTAACCCACA GGTATGGGAC ACCTCTACTC CCTCCCTGGC AACAAATCAC ACCCTCATTA CTATCCCATT AAAACCTAAT CACCCTTACC TGGGTCAACG CCAGTATCCC ATCCCACAAC AGGCTTTAAA GGGATTAAAG CCTGTTATCA CTTGCCTGTT ACAACATGTC CTTTTAAAGC CTGTAAACTC TCCTTACAAT TCCCCCATTT TACCTGTCCA AAAACTGGAC ATGCCTTACA GGTTAGTTCA GGATCTGTGC CTTATCAACC AAATTGTCTT GCCTATCCAC GCCATGGTGC

CAAACCCATA TACTCTCCTA TCCTCAATAC CTCCCTCCAA AACCCCTCCA TAACCCTTAT TCTGTTCTGG ATCTCAAAAC ATGCTTTCTT TACTATTCAT TTGCACCCTT CATCCCAGCC TCTCTTCACT TTCACTTGGA CTGACCCTGA CACCCATCAG CCTCAGCAAC TTACCTGGGC TGTACTGCCG CAAGGCTTCA TGGACAGCCC CCATTACCTC AGTCAACCCA AATTTCTTCT TCATCCATTA CCTATCCAGG CATAGTTCTT CATGAAAACA CACGTGCTCT CCCTGCTGAT CATGTCCAGC TAATCTCCCC AACCCCAGGA CTGGCAAATT GACTTTACTC ACATGCCCCA AATCAGGACA CTAAAGTACC TCTTGGTCTG GGTAGACACT TTCACTGGAT AGGTAGATGC CTTTCCCACA GGGCCTAAGA AGGCCACCGT GGTCATTTCT TCCCTTCTGT CAGACATAAT TCCTTGGTTT GGCCTTCCCA CCTCTATACA GTCTGATAAT GGACAAGCCT TTACTAGTCA AAGCACGCAA

GCAGTTTCTC AGGCTCTTGG TATTCAGTGA AACCTTCATA CCCCTTACCG TCCTCAATCC TTAGGAAAGG TAGAACTGAT TAATGGTCTT TTAAAAACAC ACCTCACCAA GCTCAGCCTC CAACTTAAAA AGGACTGGAC AGTACTTTTA CCACTTGCCA TTCTCAGAAT TCGGGCCTGT CCTCGAAATG CTACAAGGTA CAGCCCATTT AAGATTCTGT ATGGACGCTC CTTTTTATTA GGCCCCAGTC TCATTCCAGA CACCAGCCCA ACTTGAACTG TGCCCCAAAA ACTTGTCATC CCTACAATCT TCTGTCTAGT CATACTCCTA TTCACCATTC TCAACTACTT GTAAATGCCC TGCCCTTTTT TACAGTGCTG ATTTATACTT TTCCTCCAAA CCATCATAAC TGATATCTCC TGGTTTTACC TCAAACCGCC ACCCTTAAGT CTCTCTTAAA GTGGATAGAA GATCTTCAGT GACAAGGTAC ACTCCAATAC TTTCACCCTA ATAAAGCCCT ATTCTTTACT TTTATATTCA CTCTTATTCT

TGTTCCCATT CTTATGCCAC TCTCTACCTC TCCCCAGCTA TCTCCACCAC ACTATCAATC TCACTCACTC TCTCCTAGCC ATTTCTAATC CTTCTTTAAC AAACAATTGC TGGCTTTACA ATTTCTCTTT CCTCCAAAAT CACCGAGTCC TCAATTTACT CACTGCTAAA AAAGGGGACT CTGCATATTT TTAAATGAAG AGTGTTGTTT TTACCTAAAT CAATCTGGCC TGGTATATGA CAACATAAAA AAAACTCAAG GATAGAGCCA AAAACCTTGC CAACCAAGCA AGTAATTATG CTGAACCCCC TTGGGCACTC TAATTAGATG TCCTGGGTTC TCCCGATTCT TAATCCTTTA ATACCTGTTT TTCTCCTTCT CTTATGCAGA CCTTGTGTCT TCCATTTAGT TTCTCAATTC ATACAAAACC GTATCCAGGC CATCACCAAT CATTCTATAC GACAAATGTT TTAAGGGAGG AGACCACCCC TCATATTGTC TTATGCCCAA TTTCTGCCTC CAAAGAAAGA AGTAAAAATG AAAAGGCAGA

AATGAAATCC ACAGGCAGAC AGCCTGATGC CACACCCTGG GCCTGGTGGT TAAGATCAAC CCCTGACCTA ATCAGTTATG TTATCTATAG ATTACAGACA TTGTATGGAA AAGCACTGTG AAAATCCCTG TCTTGTTCTG TTCCTCTAAT TACCAGTACA CGCAGCCCCT AGTCATGTAC CCCCTGCTTG CTCCCCCTGC TTGCTCAATC AGTCATGACC CTCTCACGCA GACCCCCTTA GAGTTGTAAG CCCTTAAGAG GAAAAGGAAT TGTTCACTCG GAGAGCTCGG TTTTTGAGAC ATGAGTCTTG CCAATGCTCC CAGCTGAATA AAGCCCTTCC TTCTTTAACT CAGTGTCTGA GGGGTTTTGT CTGTGTCTTG TCCTGCTACA GTTTCATCTA ACAACCCCAT AATATCACCC CTTACCACAA AATCTTCCTT CAGCTTAATC TCTCCCACTC TAGGTTCTCA CGCCACCCCT AATCCTGCTC GAAGCAGCCC TGAGAAACAT CGCCCGTTAT CTCTCCACAC CACCCCCAAA AATTTTCACT

GCCCCAACAC TTTACCACTA TTTCGTTTTA TTTTTCTTAT TAATATAAGA AGATAGAAAT GTCAGGCCTC TGAGCCCAAG CCTGCACGTA TACATCCACA TGGCCTGAAG CAAGTGAAGA ATCACAAAAG AAGTGAAAAT GGCTGGTTCC TGCCTTAACT GATGATATTC CACCATTGTG ATTTGTTCCT GCGCCACCTT GACTGAGGGA TTAACCTTGT GAAATTCCTT CCGCTGGCTC AGAAGCTCCC CCACTGAGCA CCTTGTGACC CCCACCCCTA CCCACAAGTG AAAAACCCCC TTTGACTGTA ATTTTCCACT ACCCACCCAA ATCCTATAAA ACAGCCCCAC CCCATCTCCC TTTGCTGACT CTATTTTTGG ACTCAGCCCA CCTGCACCCA GGTGATTCAA AAGCTTCATT GCTCACACAA AGCCTGTTTG GTGGTCTCTT CACACCGACA CGCGTGATAA TTATTATATT ACTTTTAACT AAAACCCTTT CAGAGTCTCG CAGGGAAGGC TGTATATATC TCATAAAATG TTGGGGCCCA

CTGGATCAGA CAAGGCCACA AAGGCCAAAG GGAAGTAAAG ATCTCATTAT TTCTCCTAAT AATTTCCCTG TCCTTTGTCA TAAATGGTGG GTAGGCTGTT ATGGTGATGG CAGATTTTCT TTCCATAAAA TGTCCATAAT AGGACATTTG AACAGAAGGG AAAAATCAAA TTGCTGAAGT TGAAAGAGGG CAATGCAAAG AACTTTGGAG AAAGAACTGT ACAGAGAAGT CAACTGGCAG ATGGGAGGAA GTTTAAGGGG AAAAATATAG ATGTCTAAAG AATACATTTA TTCATTTTCC ACAGTGCAAT TTGGACAAGA AGCCTCTTTC TTGCTTCTTT CTATTCTCAT TAAATCATTA GAGCTCAAGC AATCCTTCTG CCTCAGCTTC CCGACTAGCT AGGACTACAG GTATGTGCTA CTATGCCCAG CTAATTTTTT AAAAATTAGA TTTTAATTTG GTGAACTATT TCTGTAGGAA ACTACAATAA TACAGCCCAG GCACATTGAT CTTGGGTGAA CAAATCAGAA GGAATGAATA ATTCTGTGTT

CCTGGGACTC TGACAATTTC ATGAACTTGG TACTCTGAGT AAAGCATAGG AGGAGTTATT TCATAAAATG TGGAGCACAA TCATGTGACA AAGATAATGG GATCCCCATT TCATAAATAA ATCTGAAGTT CAGAGAGAGT AACAACTGGC CAGGGTCACA TCACGGAGAC AGAGGCAGGG TTCCCACTGA TGCCTCTGAC TCCCTGTCCC AGGCCCTTCC TCCTCCCGCA AGCAGAAGTG CAGGGGGCAG AGCTGACCCT GTGCAGTGAA AATCTGAGGG CTGAGTTCCT ATTGGAACAC AAGTGAAAGA CTTCCTGGCT TCTAATCTCA GGATAAGGAC TCAGAGCTCC ATCTGTTCCA GCCTTAGGAT AAGAACCAGA ATCTTACACC ATGAAAGCAT GAAAGGTAAG ATTTGAGTGA GGAAAAAAAA AAAAAAAGTC TGTGTTTCAG ATTCAGTTCA CAAAGCAGTT TCATACTTAA GGTACCATCA CAATAACCCT GTGGGGTAAG CAAGGCAAAT TTCATTCTTG TTTTATGGGC

ATAGGAAGTA AGTCTCAGGG AGGTTAAGAC CAAGGTTTCT GGAGAATTTT ATATTATGAA TCTTGATTTA TGGGATTACT ATTATGTAAT TCCTAAGATC ATATAGGAAT CCTAGAGCTT GAATATAGAA CTTTATTTTT AAATCTATAT ACATCATAAT TACAAGGAGT AGTGTCCATT TGGGTTCCTT GGCCCTGATG TGTTAGTGGA ATAAACATTT TTGTCAGGGT TGCCATGTGT GTCTGTGCAC GTGTGCACTG TACACCTCCA GGGGATGTAC CCTAAACCAC ATGAATGTGA TTTGCACATC CAAGATTTAC AGTGTACTAT AGGGAGAATC TTTTGCAACA GCTTTTGCTA TAATACAGAA TCTGAGATGT CTTTGAGAAA GAAAAGTGTA ATCATTACCA AAAAATTATT CTCATAATGT GTGCAAATTT GTATGAAATC TATATTGGCC ATGGGACAAG GAGGTATTTC CAGCTAGCTT CTGAAAGGGC TCTATTCTCT CATAAGAATT CAGCTGTTGA CATTAGGTGA TATCTGCCCA

GGTCATCAGA TGCCATAGAG AAAGAGGGTT TGCTGAAACT TATATCAGCA GTGCACTGTA TGCTCTTTCT GATTTATTTG AACATTCATT TATTGAGTGT CAAGTAATGC ACTAGATACT CCAGGGATCT GACACAAACT CTGCCCTGAA GGAGCATGTA ATCTCACTGG GGAGAAAACA AAACATATGA TAATTTCAAA ATAACAAACT AGGCAAACTA GTTAACACTT AAAAAGCAGG CTTTATTCAA ATGCAAAATT GCATGTTACA GGGTAACCTT TCAGTAAGAA GCCAGGAAGA GGAGCTCATC ATGGGTTGGA TTAGTAAAGG ACTAGTTATA AAAGAAGTGG TGGGGTTGAG GGAGGCCTGA GATGAAATTT AAAGAATATG TAGAATCTAG GTAAGTGGAT AAAAGGTCTG GGGGCAGGGG AAAGGAGAGC ATTTCATTGT GAATCAAGGA ATTTCTCCAC CTGTTTTAAC TCTTCCATAT GACATCAAAG AGATGTCACT TGCAGCTAGC ATTTCAGTGA TGTTTTCTTA

CTAATAATAT CGTGATAAAA GAAACATTGA CTATAAGAAA TAGGAATGGG TCTCATAAAA GGAAACAGCA AAACCCCCAA ACTAAAAAAC AGCGCAGGCT ATTTCTCTCT TCTCTCCTTT TGCTTGGCAC TCATGAGATG CTAGGTGTGG AAGTCAGCCA ACTGAAAAAG AGAGGTGGCT GAAGAAGGTG GGGAGGCTGA AGCCAGTTAA ATAGGATGGT CCAATTCACA GACGGCGAGG CTACAGTGCA AATAGGACTC TTTCAACTTG AGCAGGACCC CATTACTTCA CTGGAGTTAG AAAGAAAGGA GAGCGTAGAC TTTTTGAACT TTCTATAAGA GTGTACCTCC ACAGTATACA GAAGACGACG TGAAATTTGA TCTGCAAGAA AACTGAGTCC ATATTCACAT ATGTATCAAA TTTGCACTTC ATTTAGAAGT GTCTGTCATC AAGTACAGCA CTGAATTGAA ACTGAAAACA AGAGTCAAGA AAGAGCAAAG TCAGCCATCT TTATATTCCA CATGAATCCT TTCCCTTTAT GGTCTTATTT

GTTTCTCCTC AGAAAAGACA AAAAGCTGAG CTGTATAAAC ACCTGTGGGC TGGGGGTTGA GGGATAAATG AGGGGCGAAA TGGAAGCTGA AGGAACTGTT GGTCAGGTAG AAATCTTCCC AGATGCACTG AAGGAAACAC ACTTCATGTT TGACGTAGGA GGTGCCACCA CACAAAACGT TTCATGGAAG GATTTAAAGG ATCTCATGAT TTTTAGTATT CCAAGAATTT TCTTTCACCA AGGGCGATTT AATATGGGTC ATTCATACTG AAAGAAAAAC AAAAGATAAT AAGAGTTTAA AAATTGCAAA ACTTGGAGTG TTAGTAGTAA AGGTAAATAT TCATTAGAGA TGAGAAGAGG AGCAAGGAAA TGCTTTCAGC TGGAAATCTC AGACAAGAGG CCAGGCTTTA GGAACCTCTG AAGATGAACA AATGTAAGCA AACCCTAGTA GCAGCACTTC TCAGATTTTC ATGTGCTTAC CACTCAGAGA TGGTGTTAAA ATGCAGACTC TGATTCAGTA GGTCTGAGTG

GAGCCTGAGA TTCTGCACCC CTAACAAGCT CTTTAGTGAT GCTTATGCCA CTGGCGCACA GACCCCACTT GGAGAAATTT TTGTGGTGCA TACGGTCTTT GTCTCCAGAT CTAATGAGTC TGAAGGACAG TGTAGATTGA TTTTTTAAAT TTATGTTTAT TTTAATTTAA TTTAATTTAA TTTATTTATT TATTTATTTT TGAGATGGAG TCTCACTCTG TTGCCCAGTC CGGAGTGCAG TGGCACGGAG GCAGCTCATG CAACCACGGC CTCCTGGGTT CAAGCGATTC TTCCGCCTCA ACTTCCTGAG TAGCTGGGAA TACAGGCACG TGCCAGCACA CCCAGCTAAT TTTTGTATTT TTAGTAGAGA TGGGGTTTCA CCACATTGGC CAAGCTAATC TCAAACTCCT GACCTCATGA TCCACCTGCC ACGGCCTCCG AAAGTGCTGG GATTACAGGC GTGAGCCACC GAGCCCAGCT GTAGATTGAT TTTGAGCAGT GGAAAGTCAA GGAATTAGAA GGCATGCTTA AATGGAAAGT

GAAATTGGAG AAAATTTAAA CTCATGAAAT AGTGGTGGTT ATAAACTCGT GATAAATTAT ATCCTGGGAT ATAATTTAAT GAGATGGTAA CACATTTAGT TTAAAGAAAT AAGTGACACT TTTTTTGTGT GACACAACTG TCTTATTCTT GGAAAGGACA AGGAGAGAAT GAAATATGGT ATGTCTTCAC AGCACCTTTC AAAGGGAGAA CCAGATTCTG AGGAGCTGGT CTCATGATGA ACTGTCAGGG TAAACCACAG TTCAGCAGCT GCAAATGTGC TTGCCAAAAT AGAGACAAAA AAATGTTTCT GAAAACAAAA TTTCACATAT GCCCTCCTCT GAGGTTGGCA TCATATCTTC CTGTGTATCT TGGGTGTAGC TTCTATCCTG CCAGAATTTA GACAGTAGAA ACCAAATGAG GTGATAAACA GAGTCATTTT GCAGAAGAGT CAAAATAACC CAGCAAGAAA TGAAACCACA AATGCCCAAG GAGTCATTCA TTCACCATTC AAAAGCTAAT AGAAATGAAC ACAAACTACT ATGAAAATTC

ACCCAAGAAC TTAAAAAAAA AAAAAAAGGC TCATGGTGTT TAGTGTGATA GTATTCATTT TACCTTTGAC TTGTTCTAAA AACACACCAT ACTTCTACCC CACCCTTCCT CAGTGCCGTC ACACAATGGT TTCAGTGTGA AAAAAAAAAC CACGTTACTG GAAAAGGAGG GTGCCTGGGA CTTGCCACTC TAAGCTGGTA GTCAAGGGTC TTGAGTTCTA AAAGCATACG CGTTAAGAGC ATGATTCCTG GATCCAAATG AGTATGGATC TCAGCATTGC CATTTATTGT GACCTCAGGC TATTTTATTT CTCTGTGCCT GTTTCTTTAT CAGTAATGAA GATGTTCATA GACCCTTCTC CCACAGACTT AAAGGCATAT TTCATGATTT AAGACATGTA AACCATTCAT AACAGTATAC AACATGGAAT TAATATTTGA TAAAGGTTTA TGATTATTGT AACTAACTCT GTCACTTGCT CAAGGCCTAT AGAAAACTTA CTTAATTAGT TCAACTACAA AAAGAGTTTG AATGTGATAT CCACCAAGAT

CATATTCAGA CCTAGAATTC TGTGATTCTT ATGAATTAAT ACAGCCTTGG TCAATAAATG AGAGCTGGGC AAATAATTCT TCTTTGCTAG GCCTTTCTAG ACCATCTGGT GAAGCATTCA AGACTTATGT TATTGGGGCC AGCCTTCCTT TCCAACTTCA ACTCCACAAC TCCTCAATAA GCCATGGGCT CAAGAAAGTT CTGCTCAGTG GCCCCTGAAA AATGCTTTCA TAGTCTCACT ACCATACCAC TGCTTACACA ATTTCCTTCC TACAGACTGC CTTCCTTTCC TGCTTTTCTC CATATACCTA AATCCTATCT ATTCTTCATA AGCAACCTTC TTTATAACAT TTTCTATAAC CACCAAGCCA AATGACCTTT TCCTTCTTAA ATATAGCACC CATTGGCCAT TACCATGCTC TGCCTTGTAT TTTTCTGATT TTTTTCTTTC TATATTCCTG TCTTAACTCC CCAGCTAGGT AATAATTTTC CTGAAATCAG GGACCAGGCT GACTCCTCTT GCTGTCTCAA GAAAGCTTAG CAGTTTCCAA

CACAAAAATG TTCAATAAAC AACTATTAAT TGACTGATTA TAAAAAATCA GTGAACCATT AAACTTAATA TAGCAATTTG CTTAGCATGG TAATTAGCTT TTTGCTAATA TTCTTCCAGC CAGTCTCTCC TCCTGTGCCT CAAGGACATC TTAAAAAAAA AAAATCTAGT TGATCTGCTT CCATCTAGTG GCAATTAAAA CAGGTGGTTC CGGTAGCCAG AAAACAGCTC TGGGTAGATT GTGGCAGAAA ATACTTTCAC TCAGTAGGTG CGAGTTTGAA AGAAATCTTC ACATCTGTGG GTTTCCTGCC ACAGACATAG GGAGACCAGC CCAGAGAAAG AAGCCTTTCC TCACTAGACT CCATTTGCAC TAGTAAAGAG AAGACAGAGT AATTAAAAAG AATAAAAAGA ACCTCCACTG ATCGTACATC CTCATCCAGT TACCCCTGCC CCACTTCTCC TTCACAGCCA AACATTTTAA AAGAGATGAC TGCTTGTTCT GTCTCTACTT TCTCATCCTC AGTAATGCTC AATGCTTGGC CGTCTGACCT CTGTCTTGAT GTCTGCACTG CAAATAGTCT CCCCACTGAC ACCCTTGTTG CATCCAGGGG ATACTTACTG GTTCTCTTGG CAATGTTTGA AACCGTTCCC CTTTCTTTGT TTCCTTGGCA TTCATTACCC CACACTCTTT CTCCTCTTCC TTCTCCCTGC CTGGCAACAT CTTTTCATTT CTCTTTCCCT TAGGTGACTT ATTAGATAAT GATGTTCCTC TGGCTCCCAT ACTCTCTCCC AGGTCCTCTT CCATTCTTAA AGCACTCACA CCCTCCCTGG ATGATAGTAC CCACTCCTGA GATGGCAGTT ACCTCCTGAA ATGTGAGGGA CCCAAATCCA CTTCTCCTGC CATAGCCTCT GTGCTTTGGA TAGGTCCAAT GAGCCACAGT GAATGATGTG CATACACCCA AAGCTCAGTA CAAAACTGAA CCCATGATCT

TTACCTCCAA AACCTCTCAT TCTTTTATGT TCCCTTCTCA GAAGTAAACA GGACTACCAT CCGCCAGTTT CCAGGTGAGA AAGATGATAA TTTGATTCTT CTCTCTCACT TTTAGCCAAT TAACAGACAC ATTCAGTTAA TATCACCTCC TCTTATTTCA TGAACCCATT CTTACTACTA GTTCCCTAGA CAGGCGCCAT CGGTTTTAAT CTAATAACTG CAAATGCCTC CAAAACAAGT CTCTTTGAAT CCAGGCTCAC CTGTCTCCCA CACTTGCCAT ACTGCTCTGC AGGGTGACCT TATAAGATGC CAGAGGTAAG GCTACTCACT GTTTAAACCC CTTTAGTGAT ATCCCAAAAG ACCTCAAGAT AAAGCCCATA TCACATGGCT TATACATTAG TTTATGATCT GGCTTCTGGT GCCTCATTTT TCCCCACTTT TTCCTTTGCA TTCTAAGCAA TGGCCCATAC TAAGTTTGTG ATTGGTAGGA TGGTTGCCCA AACCAGCATC CAATCCCTTC AGAAATCATC TCACTTCATT TCTAGCATTT

TAAAGGAAGC TCAGTTGTCC AGCTGGGTAC TGAATATGTC ACCAAAGTCC TCCTTTCATA GTTTATTTTA CTTAAACTCT CCTTCCTAAA ATTCCAGAGC AAGTCACTAA ACCCTAGATA CTGAGAAATA TTTTTCCATC TTCATTTCTG CCAGGTGGGC CATCAACTTT CACATGTCTG CATCTCCTCC CACTGTGCTA TTTCTCCAGT AGAAGAAATT TGAGCTTCAA GACCAAACTG AAAAATACTT GCCTCCTTGG GGAAGCTGTA GGTAGAATTC ATGCTCCCTA TCTTTCCCAC ATTTCTGAAG GACAATGCCT GTTAGAGCAA TTGAATGCAA ATAGTCAATT GAATAAGCAT TTATTCATTT CTCAATAAGT GCTTGTTCAA TTGAATATTT CTTAAATAAT ATATTTAAGA ACAAGAAGAA CACACCACAA TGTTTTTAAC CCTCAGAAAA AATTCTGAGG TAATCAGAAA AATCTCCCTT TACATAAACT GCCCTTTTCT AATAGGGATT ACTTGTTCGT TCATTCATTC ATTCAGCTCC

ACTAGCACCA AAAAGCACAG CTCTGAAAGG AAGCTAGTAG ATTTATCACC TTATCTGGTC ATTTGGATGA GGACCCCAGG TAAATAAACT ACTATGGGGT TAATGTGTCT AGCTAGAGCA GGAAGTAACT TAAGGAAGTA GAGAATGAAT CAGCAGATGT GGAAACTCCT CGCCACTAAT AAAACTTACC TTCTCTTGGA TTTCTTGCCT GAAAATAGAA AATAGAGAAA AGGCATTAGC AAAAATTAGA CAATTTAAAG TTTTTCAAGT AAGGGAGAAG GAAGACTCCC ACTCTCAAAA CTGTCTTTTG AAGTATATTA GGTATTTGTT AGGTGGACCC TATCTGTGTC AAAGGAGATT TGAGGAACTG GCTTAATAAA CAGTGGTAGA CACTAATACA GAACAGACAT GTTGATGCAG ATGCCTCCTG AGGTTCCATT CCATTCTCCG TGCTACTCAA GAAGACAGAA 25441 TTGCTAAATT GCCTGGTGGC AAGACCCAAT ATGTCCATTC AAGTGTTTAT CCCTTCCCAA TCTGCCATCT

CATCCTACCT GCAGATTCTT CCCTTGAGGG ACAGCTGCTA ATACTGTAAA ACTATGTGCC ATTACAGCTC ACAGCATCAT CTCTATGAGA ATCCACAAGA GAATTTCACT TTGGTCTTGT TGGTAGGAAT TGTGCAGCCT CATCTGAGTA ACTAATGTGT TTTTATCTTA CAAACACAAG GAATATCACA TGGTTCTCCT TTGACTGGCT GTAAGGAAAC TCAGAGCTAG ATCTGAGACC CTCTCCTACC AAGTATATAA AACTTTGTGA CATACATTTT TGTGCCATAA CTTCAACCTT GGTTCCAAAT GATTTTTGTA CCCTAAGTTT AAATTTGGCT TTCTTTTTTT TTTTTTTGTA CTCAATAAAA CATCAAGCTC ATTTATTATT GCGAAGAGCG AAACAACAAA GCTTCCACAG CGTGGAAGGG GACCCGAGTG GGTTGCCCAA ATTGGCTTCT TTTTCTTACT TTTTAATTAA TTTTAATTTG CTATACTGAA CACATTTTGT ACTGTTCTCA CATTCTTTTT GAAAAAAGCA GAATATAAAT

AAGTAGATAA CTTAAAAAAA ACTCTTTGAG CAGAAAGAAT CATTTGGGAG GCAATATATT TCAGTGGCTG TAAAGTGGCA TTCTAGAATC ATCCTACCCA GGTGAAAGCC CTATTTTGCC ACCTGTAGTG TAGTGTGTAT TTGAACAGCT ACTTTCTTTT CTAAACTACA ATTTCTTCAT CTGTTAAAGA GGCATAATAA TTGTATCATC CTCATTGGGT TGATAAAATA AAATATTTCC AAGTATTTAG TTCAGGTCCT AGCACGTAGA CAGTGTTGCA TTACTGTTTT AATCCTTTAA AGTATTAAAG ACTACTATTT GAAATCTTTT CTTCTAAAAT TCAGCCTGCT GATGACCAAG TGCACTTGAG CAGGGGGAAT CAAATCTGAA TTAATTTCAG ATTCTGGTTA GCTTCACATA AATATTTTTT TTAGGGATGA TGAACCTAAC AGCAATAGAT GAGTAAGAAT CTGTTCCTAC TGAGAGAGTT TCATTTTGAA GAAAAAGGAA CTAAGGGGGC ATGTGTTCAG TTTCATGCCC TGGTCTAACC

CTGTGTGTTG GTTCTGGTGG GAAATTCTTC CAACCGAGGA AAAAACCAGT TCACAAATCT GAAGACCAGT GATTTTAGAA GATGTATCTG GACTGGAGTC TAATCTCTGA CTCTGGGTCC TGCTGATATG GTATTTTTGA GATTTGGCCT AAAACATCAT TGCCCTGGTT TCCTTATTTA CCAAACAGGG CCAATGGTAG TGACTAATCA GAAAATGATA ATGCCTGGTG CACAAAATGT GTCTAGATGA GCCCATGCAC AAGGACACAT GTTTCTGGAA CTGTTCCTTA TTCCTTTCCT AAAAGAAAGG AGGGAAAGTC TCCATACTAA GACTACTAGG GCAGGGGACA AAGTGCTAGA GTCAGAAGAT TCATCTGAGG ACAGAAGAAT AGGGGTGAAG GCTCTAGTCA CTTCATTGGC TACCATGCTC TAAATAGTTA CCTGTGCCCT TTTTCTAACT ATTAGAACCC AAAAAGCCTA TAAATTCTCT CTCTCTCTCT CTCTCTCTCT GTGTATATAT ATACATATAC ACACACACAT AGACACACAC

ACACACCTAA ACACACACAT AGAGATTTAT GACTTTTTAC TTTTATCCTT GTAAATGCCA TTAACTATAT TTTGTCTTAG ATTTAGCCTG GGAATGTAGC CATTATTTCT ACCATTGCCT CCATAGGAAA AATACTCTTC ATGTTTTAAA GGACCAACCT ACAACTAAAA TCTTTGGAAA GCAGAATCAT TTGTAAGTTG GTGAAAATGG AAGATGTTGT TTTATAAATG AAGACTTTTT _TTTTχχχ_TTT xxxxGAGACA GGGCCTCACT CTGTTGTGGA GTGCAGTGGT GCTGTCATGG CTTACTGCAG CCTTGACCTC CTGGGTTCAA GTGATCCTCC CACCTCAGTC TCCTGGGTAG CTGGGACTAC ATGTGCATGC TACCATGCCT GACTAATTTT TTGTATTTTT GTAGAGATGT GGTTTCGCCA TGTTGCCCAG GCTGGTCTTG AACTCGTGGG CTCAAGTAAT CCTCCTGCCT CAGCCTCCAA AAGTGCTGGG ATTAGAGGTG ACAGCCAAGG TGCCTGGCCC ACAGATGAAG ACTATTTAAT

GTTATCTTAA AGATACCCTA AGCTTCCTAC CAAGCCAGTG ATCTTTTGGG GCTTCTGTTT TCTTTGTTGG CATAACTGTA ACTAGCCTAA CTGCCCGTTA TCTGTTTCCT GTTTGCCCCA CACTGATTCC CACAGCAGTT TTCAAGTTAT CGGTTTGAGA TCTTGTACAG AAATGACTCC AAGGTAAAAA ATTTAAAAAC AACCCCTCTA ATTTTTTTAC CCTTGCTTAT AAAACAGCCT TAGCCAGCTA ACCCCTCACT ACATGCAAAT GAGTTTGATT CTATTCTTTT GATTCTACAA ACACTTATTA AAAGATTTTA GAATTCGGAA ATAAATAGCT TCCTTATTAA GGTGACTTAC AGCCCCAAAG TCCTTAAAAT TATTTAGACA ATAGCCACCT TATCCCAGGG GGCAGTGTGT AATAACCCAC CCTGTTCTCT ATCCGTCAGT TCTGCCATCA TCGCCCAAGG TAGGAAGAAA GACAGGACAA CCGGGGTCAA GATTTGAAGT CTCAATGGAA AGAATAATCA GTGGTTGGAG AAAACTGTCA

TTCTTCTTTT GCCTTAATGC AGTACTTGAT ACTTATACTT AGTACTGTAT AGTACTTAGT ACTGTATAAT ACTATAAGAT AGTGAGATTC AATCAGCACA GAATTTCTAA TAGCAAGGGC AGAGACATTT TAACTGCTCA GTGCTCTCAG GTTATACATA GCTAATGAAG TTCTTGCATA TCAACAATCC CCACCCCCCT CACACACTTT GTCTTTCTGG ATTGGTTAGA AAACTTACCT AGCGCCCACT ATTCTCAAAT TTAAATGAAA GATAAGATCA GAGTGGCACG CAATTAGGGA CTGATAAATA ATATTTTTGT AATTGCCAGT GTAAATGGAC AGGGGGCAAC CTTTACATAC CATATTCAGT GAACAGAATA CGTACTAACT AATTTGATGG AAGGAAAATT AAAATGACAA TCAACTGAGC CCACAGAAAG GCAACACAGA GCAGTTGGTT AGCAATTGTT TCGAGATCAT CCCTGAACTT GAAACAGGTA TATCTTTTTT χχχχ_Tχχχχ XXGAGACAGA GTCTCACTCT GTCACCAGGC

TGGAGTGCAA TGGTGCGGTC TCAGCTCACT GCAACCTCCG CCTCCCGGGT TCAAGTGATT CTTCTGTCTC AGCCTCCCGA GTAGCTGGGA TTACAGGTGC CCGCCACCAC GCCTGGCTAA TTTTTGTATT TTTAGTAGAG ACAGGGTTTC ACCATGTTGG CCAGGCTGGT CTTGAACTGC TGAGCTCATG ATCCGCCCGC CTCGGCCTCC CAAAGTGCTG GGATTACAGG CATGAGCCAC CACACCTGGC CAAAACAGGT ATATCTTAAA AGCTGCCCAA TGTCCATGAA TGTTACAGCC TTGAATGGTT CTTCCAGGTG AGTTTGGCCA AATGTGGCAC CATACACCCA AGGCCTGCTG CAGGCTAGTG GGTTGCTCAC ACTTTAAAGC TGAGACACAC TCATGCCTTA AGGTAAAGGG AGTGATAATC TGGGCAGCAG ATGTTAACTT CTCAAGGCAG TCCTCCTTCT CTTTTCCTCT CCAGTGACGG ATGGTTGGAA AGCATATATG GTGCATTTGG TTAGAGCTGT GGCCTTGGTG AATAGATACT

TGGGAGAATA CATGGGAATT TCTCCCAGGG TTAATGCAAT GCCCATGTGT TGGGAACCAG GTGACTCTTG AAGAGGTCAG GTATTTGGGA GCAGTGCCTT GAAACCTTAG TGGACATTAG ACCCACTTCC TAGTGGAATT GTAGCATTGA AATCCAAGGC ATGTAGGCTC TTAGAGGACA GAGATAGTGT GTCATTTTTT CAGAATTAAT TAAGAGCAGG CCAGGCGTGG TGGCTCACAC CTGTAATCCA AGCCCTTTGG GAGGCCAAGG CAGGCAGATC ACGAGGTCAG GAGATCGAGA CCACTCTGGC TAACACAGTG AAACCCCGTG TCTACTAAAA ATACAAAAAA TTAGCTGGGC ATGGTGGCAC GCTCCTGTAG TCCCAGCTAC TTGGGAGGCT GAGGTGGGAG AATAGCTTGA ACCCAGAAGG CGGAGGTTGC AGTGAGCTGA AATTGCACCA CTGCACTCTA GCCTGGTGAC AGAGTGAGGC TCTGTCTCAA AAAAAAAAAA GTATTAAAGA ATTACATAAG AGCAAAGAAC CATTAGAATA

TCTCACTTAG TTGTTATCAG CCTAGCAAGC TGCCTTGAAG GTAATAGACA TTTTTAAAAG TTTATCAGAT GAAAAGCGAA AATCAGCCAA CCTGTTTTAA TGAAGGTGTG TCCTGGGCTG ATTTACATGT CTCCAGGGAC TGATGGCTCT AGAATGTAAA GCTTGGCATC CTGCTTGTGT TGAATCTATC ACATTTAATT TCCTGTGGGT TTCTTTTTTT TTTCTTTTTC ACTTTAAAGT TGTGTTCTTT TCATGTGAAG TTAAACTCAC ATACCTTTTT TTAATCTCCT TGCCAGCCAA ATGATAAATG CCAACCCAGA GAATGCAGTA ACCATGACTG CCACTGGAAT GAAGAGGGGG TTATAATCAC CCTCCTTAAT CATTGAGAAA CTTTTGTCCA ATTCTGAAAG AGAAATCAGT AAGGCACATA GCATGAGACC ACCAGCATTA TTTCCTTAGT CTATCTCATG ATATTTGACT TTTTTCCTCC TTACATCTCC CAGTAGTAGC CCATTTGATG CCATTTGACA GATGAGGAAA CTGGCATGGG

AAGGCCCCTG ATGAGTCTAC AGCATAGGCA AAGACTGGAC CAGCCTTGCT AGTCTAATGC CTACAGAATC TCAATGCCCA GATTTGTGGT TCATAGAGTT CCTGAAAATG CACCTAAAAA TGTTGGCAAG AATGGTCATC GTTGTATTTA GCTCCATGGA CTTGTTCAAT GACTGGAACT CTGAAACACA GAGAAGAGCT AAAAGCCTAA TACAACTTCA GGAAAAATAA AAGCCAATGA TCTGAACTGG ATAATTCACC AGTCAAAGGA AATCATTAAT GCTTTTACTT TAAAGCAGTT GTGCAAAAAT AAGCACTTGA TTTTTACATG CCAAGGACCT GCACTAATTT CTTTCCAATG CAGTAGTTAC CACTTCCCTC TACTTCCTTC ACGAATAAGT AAAAGGGCAT GTTTAGAGAT ACTCTTGTAA GTGTAAACTA AGTTCATTTG GGAGCCTCTA TTTGAAAATA CTGGTATAAA AAAAAATCTG TCTCCTGATA CTAACATTTG AAGGAATCTA CTTTTTTACA TATTGGCAGA GGGTCTGATT

CTATCCTTAG TTCTTCCCAT TACTTTGATG AACCTTTTCA AGGTGATTTG ATCCCCACAC CCAAATATAT GATTGAGAGA AGGCTCAAGT TCCCAGGAGC TCCAGACAGA AGGTACCTGT TGGCTTGATG AAGATGAGGA GGAAATGAAC ACTAGCTAGG CCTTAAAGGG AAATGTCTCT GATAGGCCTA ATACACAGTC CTCTGCTAAA GGCCTCCCTG CCTCTCTCTG CTCATCCACT CTACTCCCTG GCCCTGGGCA CGCAGCACAC AGAGATCAGC ATTTCTGACA GCTTCTGTAG ATCCTACCAT TTAAAGACTT TTGTCATCCA TGCAGATAGT CTCAGGAGCA GACACAGGTA GCTATTCTTT CACATGCTAG CTTAACATGC ATTTGCTTTA GCACCTATTG CCAGGCACTG TGTCAGGTGG AGGGTATACA AAGATGAACA AGACATGATT CTTCTCATAT ACAGATAGAT TTTGGAGGCA TTAGCTTAGT GATGATTCAG GAGTATCCAT TATTTGGGGA AGTAGGTGGT CATTAGTGAC

CTTTTACAGG CATTTCAATG GGCTAACAGA GATGTTAGAT TGTAGTGGAA TAGAAGAATG GGTAAAAAGT AAATCAGTGA GTTCAGATTT TAGGAGTTAA GATGGCAAGA GGTGAGAACA AAAAAAGGAA ATGATTGTCA TTAAAGGAGG AGGAAAGACC AGCCAAAGAT TTTACAGTGA GTTAAGCATA CAAATTTATT TCTAGGCCAC ATATTCTTAG CAAAACAACA TGTAAATGTT TATGTATGTC TTTCCTCATA TCTGCTCATC CATCAGCTCC ATCGTTAAGA TTTCAGTTTT CCAGGACAAA CTTACTCACT TTGACATATT GGACTAGGAT TTGACCAGAT TCCAGATGAT TCACAAATGG TTTTCTTCTT CCCAATTAAC TCAGTTCCTT CTGAGCAGAT GAAGGTACAT GCAGAGGTAA AGCTGAAGCT GGCCAGGGGA TGGCTACAGT TCATGATCCC CAAATCTGGT GCTGATAGAG GCTCACACTG AATCACTTCA ATGAAAAAGA AAAAAAAAAA AAAGACAAAA CAGTATTTCT

GAGTAGAGAC CCTCCCTTGA GCAAAGGATT TTTAGCCAAA GCTGCCTGAC TACATTACTT GTGATATTGC TTCCAGGCTT TATTTTCTTG AGAATGATGG TGGGTGGTGA ATGAGAGATG AAGGCAAGGA AGCATTGAAA GCTGTGGGGA GAGGAGTAGC TACTCCAGGC TGCTGCCCTA GCTAAGGTGA CCCTCCCCTT CTGCTGGAAG TACCATGCCA TATGGCCTCT GCATCAAGGG CTCTTATGGG ATATTCTCAG AGAATCTCTG CCGTTTCATC TGTTCTGATA TCTACCCAAG CATTTTGAAA AACATCCCAA TTCACTGAAG CAAGTCCAAC TTCCGTAAAT TCCAGTAGGT GGGTTGACAG TTTTATAATT TCAATAAGGG ATTTTGATAG CACTTCTAAG AATTAAACTA CTTAAACTAA TGCATCAGGA GCATACTTGT AGAAAAGTTA ACCAAAACTT CGTAAGTTCA GATGACATTG GTTTTCTCCC ATATGGAGAT AAGGTTGGCA GTTAAAAATG AAAAAAAAAA AAAAACCTAC

CTTATTTCAA ACTTGAAAAG ATCAAGAGAT TGTGTTTTTG TTTTTCAGTT GTTATTCTCC TAAAAGTTTA TGCATGAGGA AAAGTAAAAG TGATTTTAAG AATAAGCCAA ATAAAACAAC CAAGAAAGAC CTCCACTACC CTGGGAAGGA AACTGGTTGG TATTAAGTAG GACACCACAT AAAACAGGTG TTATTGAGAG GAGAAGAACC AAAATGTAAC TGAGGTTCAA CAAGACATTA TTTATGCAAT GGCAATGAGA AAAATAAAAA ACACAGTATA ACCATGCTGT ATTGCTATAA GTCATGTTAC ACACTGGGAG ATGGCTTCAG GGGTATTTGG TTTTTACTTT TTGTTTGGGA GGTTTTTCAA AAAAATTTAG TTAGAATAAG TCCTTTGAGA AACATCACAG TAGGTTAAAC AAAGTTAGGT TAAATTAGGC TCCTAAGTTT GACTTCTCAG CAAACTTCTA CTGAATGTTC TGACTGTAAG CCCAGGATTG CATGACAAAA CCTCTAGTCT GAAGTTACTC ACCTTGACAG

GTTGGTTCTG GAGATGACCA GTTTCCAAAT GGTCCACAGG TGGTTTCTTC AATCCCAGTT AAGTTTGTTC CTTCAGAGCA GCTGAAGGCA CACTGTGAGC TGAAGCTGAA GTTTCCCAAA GGGTGAGTAC AGTCCATGGT ACCCAGCTCT GGGGCCTCCA AAGGCTCACA CTGAATCACT TCAATAGGGA AAGAAACAGT ATGGGGAAGA GTTAAGAGGA ACTGACGCCT GGATTTGAAT CCTAGCCCTG CCACTTGATA ACCATGTGCC TTTAAACAAG GTTACTTGAA CCCTCCAACT TCAGTTTCTT CATCTATATA AGAGGAATAA TGAAATTGTG TTATCTTTAT CAAATTGATA TGGAAACTAA ATGTAATTCA ATTAGCATAA GTCAAGGACC TTAGAACAAA GCCTGACTCA TCAGAAATTC TAAGTAAACA TTAGCTAGTC TTCATATTAT TATCTTCAGC ATTATCTGTA GTGAGAATCC TTAAAGCCAA ATAGGTGTAA CTGGGAATGA CCAGCTTAGT CGGGAAATAA CTATCACATC

AGAGCCCCTG AGTCTACTAG AGTATTGGGA GCAAGATGTT CAGAGAAAGA GTGGGTCTCC ATAATAAGCC TTCTTTGCAA GGAGAGAATA TAAAAGTCTA GGAAGCATTT TGACCTCAAT TCTGTCTTCT ATTCTAGCTC AGTTCCAGAA TTTTAACTCT TTTGATTTTG ACAACCCTCT CCAGAAACTG TATCTATTTC CCTGTTCTGA TTGGTGGTAC AATAGGTAAA TTTAAGACTT GGAAATCAAA GTTTTCACAT TTTAGACCCT GCCATGCCAT TTAGTAAACA GTACAACTTT CATGTCTTAT TCCTCATCTG TCAAATTTAA GCCATTATTG CTACCTTGCT CTAGAGACTT CAAGGAAGAA TGGACTCAAG GAATCAGAAG AATTTTTGTA TTTGGAAACT ATATGAGATG AGATTAGGGA GAAACATGGG AACTAAGAGA AAATGTTATC TTTTTTCATT GATTTAAAGA GTATCTATTA TATATCAAGC ATTACTCTGG GGCTTGAAGA GCTTAGATTT CACCCTGTAG GACAAAATGG TAGGTAGAAA TTAATGGGTG GATTGTCATG TATGTGTGAT GTGTTTTAAT TGCTTTTAAT TGATCAGTCT CCCTGTAGTA TGAATAATGT ATTTGAGGGG AGCTAATTTA AAATTGTGGA ACTCATCTAA TAAACTATTG CAAGAATCTA GAAGAAAGAT AATGACGGCA ATGGTAGTAG AGTTGACAAG TGGAAGACAA ATTAGAAAAA CACTAAGTTG TAAAAATTGG TAGAATGTTA CCCTGCATAA ATGTTGGGGG AGTTAAGAGA GTCTCATACC AGGGTGCCCA TGTAAATGGT GATTCCACAT ACTGAGATAA GAAATACGAA GAGAAAAGCT GACTGGGAAC AATTGGTTTT ATAGTCTTTT AAACATCCCA AAGGACATCC TTAGCATATT TGAGTTCAGA GCTGGAGATA GGCTTATCAG TCCAAAGATC

ACATAGATTT GTGAGTCCGC AAAAGTCAGT AAGTTTGACC AAAGGATACA TGTAGATTAG AGTCAGAAGA GCAATATACA AAAGACAAAA GCTGAGAAAT TATAGTAGTT TATGGTCCTG GATAAGTGCT CATGAAGGAT CTCAGGAGAA ATGATCACAG GTAGAAAGAA TGAGAAAAGA GTGATATGAG AGAAACCAAG ACAAAGAAAA GTAAAATGTT AAAAATGAGT GAAATAGGCA TACCAATAAT TAAAAATGAG TAAAATAGGC ATACCAATAA CATAAGGGTT AAAAAATAGA GTTCAAAAAT GGGGTGAGGG TAAAGTATTA GGAAGGAGTC ATGGCCCAGG GATCAAGTGA AATGAGTTAG ATCTATAGAT CTATTTCAGT TGGTTGACAT TTAAATGTAT TTTGGTTTTA ATTCTTTATT GTTTACAAAC ATTGCTTTTT TAAAAAATTA AATTGTCCAA TTCAATTCAG GCTCACAAGC AAGTGCCTCA TATATACAGG CATTTTGTGG ATCCCAAAGA

TGCAATGATA AATAGGACAC TTACTGATCT CAAGAAGTTT TCAGTACCAG AGGAGACGGA CAAGTGAACA GATGACTTCA ACATAAGTGG GAGAAATGAG GAAGAAATAT GTGGAGCTAT CAGAACTAAG AAAGCTTCCT AGAAGAAACT GTCTTTGAAC AATGTCTTAA AGATGACATG TTTTTTGGCC ATGTGCAAAA TGAGAGAGAA GGCCACCAGC AAAGTCAGTG TGCTACAGAG CACATGTGTT AAGTGTGGAG AACTGCAAGA AGGAAAGGAA CTACTAGAAG GAAAAAGCAA GATACTTTCT GGGTAACTCA GCCTCCTAAT GATAAATGGC ATAGTTTCTT CCAGACCTTA GAGTTCTAAT TAATCTAACA AGCTCATTAG ATCGTGAGCT TCTTGAGAGC GGGAATCTAC CATGCTAATT CCTTATGGTA ACCCTGACAG CTTTTATCCC AACACTGTGC TTCTTGTGGT ACTCAAAAAG ACTTGTTGAG AAGTGAGTCG AAACTTCATG CTGACTTATG

AAATCTTTAC GGAAAGGTAA CAATATTGTG AAAGCAGAGC TTTCTGATCA AAACTTCCCA TTTCTCAGAG TGGCTAGTAT CATTTTGTTC CAACCAGCTT CATGATAAGC TATAATGATT CCTGTGACTT TACCTAAGAA GAAGCAAAGA AAGGAAAGAG ACTTACCAAA CTGACACTGG GGCCCATAGT ACCCCACATC ACAGTTGCAG GTGTAATTAT TGATGATTTC TACACATTCT CCATGGCCAC TGCATGACCA GGGCTGGCAA GAAGCTTTAA GGAGGTCAGA AAAAAAATAT TTTAATGTGA TTACATTTTA GTACTCAAAG TCATTTCTTT AGACATAGAT AACCTTTTGT CTGAGATGAT TTAAATAATC AGGAAAGGTT TATTTGTAAA TTCATAGCAT AAAAATCATA TGCTAAAATT TTTACGTATA ' AAATACACTA AGCATATAGT CATAGGCATT TATTTGCTTT TGGAATGAAA TTACCAATAC TAATATTCTG TAACACTTAT AGGAAACTTA GTGGCATACC TTGAAACTCT

TGAAATTACT TGTTTTTAAT GAGTGAGAAG GTTAAATGAT GACCTGACCT CAATCATTTC TGCATGCAAT TATTTCTTGG CAATCCCTTT CTTTATAGAA ATCAAAGATT AAAAAGTCCA AATTTGCTAA AACGGTAGAG TCCAATTTAT AAGAGACCAA ATTAACTATG GTTCATTATT AAAACATCAC TTGGAAAATG CTGGCTGTTT TGGAATTGTA GAAGATTTTA CAGAAATATT CATACACCAA AGATAGTGCA ATTTTTATAT AAAATTATAT AAGGTTAGAC CAAGAAGGAA GCACGCAGCA CCACACTCTC TACTTCACAA TGTGAAAACT GAGGTGATGT GAGCCTAAGT TTCCAACTGG CCCCAGCTGT CAGCTTCTCC TCCCCTGCCT TATTATCAAA GGCACTGATT GTCTAGCTCT TCCTCTGTAC TTCCTACGTA GATCTATCAT TTTGATGTAA CTTGATTTAG GGGTATAGCT TTTGTGCACA GGGACAAATC TTACACACCA AAAATTCTTA GGAGTGACAC GATGCAAGAT

TATATAGAGG GCTAGATGTA TTTTAGAATG AACCAGAAGC TGTTCTCATC CCCCCACCTT TCCATGGGGT AAATCTGAGT ATTCTCTTAA CCGTGGCCCT TCCTGAGTCT GAGGCAGCAT AGCCGTCTTG TCACTCCCTA CCTGTGTAAC AGAGGGCTGC CTTTAGTTTG TGGCAGGCGT CATCGTTCCA TTTGCCTGCA TCTTTGTTTC TCTTGATATA GATCTCCACG CAGTCCTCCT TGTTCTTCTT GTTGTTGGGC TCACCATCTC CCCAGTTCTC TGCTTCTTCA GTAAGAGATT TGTTGGTTCC CACCCACGTC CATATTCCTC CTATCTTCCG GATTCCTATC CAGTAGTAAG AACGACTGAA AGGCAGAGTC TTCTCCAGAT ACTCAATTTC CGCCTTGTTT TGTATGGCAA CTAAATCTGT GTAATTGTCT CGGCAGAATC TTCTAGCCCT TTGCCAGTTC ATGGGTTTTT CAGAATAATG GTAAGTCCAG CAGTCGGTTC CATGATGTGC CAGGAAATCT GCAAGACATC AGTGTGACCT

ATGCAGACTT ACATAATGTT ACAGCTAAAA AGAACCTAGC ACTACTCCAG GCTGAGCTAG ACACTTAGAG ATGAGGAAAC AGAGCCTAAG AGTGTATGTG ACCATCTCAG GATCACAGAA TAGTTGTTTG CAGATTTGAA GTAGAACCTA GACCTTCTGG CTTGAATATA AGATGCTTTT ATCTAAGGTT CTATTTGAAA CAAATTTAGT GGTTTTCTAG GTTTATTTTC TTATTAATTT TTTTCTCAAA ATTATTTCAG GTGAAATTTA ACCAACATAT TTTAGACATT CATATTTCTT TTTCTTTGTA GCTGTTAATG ATTTACAACT AATTACCGTG TAATATCATA TAACTATACA ATTTACGTAT ACTTTTTAAT CCTGGAATCA TTTCTTGAAG GCCAACACAT ATGTACCTAT GGGAGAAGCA TAATAAGGAC AGGAAGAACA GTGACATACT TTTAAGTAAC CTCTTTTACA TAAAAAACAT TTTATTTTAC CATAGGAAGA ACTGCTTCTG GAAAAGCCCA ATATACCACT CAACTCTTAT

ATATCTAACT GTATAATTTT TAAAAAGAAC AATTTACAAA GCCAAATGGT ATAGGATTAT GAAATTCATT AGATCATGTT CTATACACAA AGAGACTCAA CTGATGATGT TTAATAAACA TATGGACCCA TCAAATATGA GGGCTTTGAA GATATCTAAT TAAACACATA ATTACACAAT GACTTCATAA TAATATATGG CATTCTAAGC ATGGTATGAT CTACATGAAT CACTATTTAA TACAGTAAAG AAACAGATAT AATTGATGGT AAAGAGCATC ATAAAATAAA CATTTTGAAC AGAGTTTTGA ATGAGCATTC CACTAGAATG CAAGTTCTAA GAGGGAAAAA ACTGTTGTGT CCACTGCTGT ATCCTTAGTG CCTAGCATAA ATTTCACACA TTGTAGGGAC TCAGAAAATA CCTGTTGTAT GAAAAGAGCA CTAAGTTTCT ATGTGACACA GTGCAGACAT GGCATAAGGA ATGTGTGAAC GGGAGAGTTA GCATGTTTGC TTGGCTAGAG CTGAAAATCC AGGCTAGGGA GAAAGAAGAC

ATTAGTTTAC TTAGGAAATG AAAAACCAAG TTCAAAGCTA TTGCTGGAGA GTCTTCAAGA ATCAGATATA AAATTTGTCA CAACAATGGG AGAAGGACCA AAAAATGATA AACCCCCGTC CCTTAATAAG CTCGTATTGT AATTGTAGAA ATGACATTAA TGTACACTGA ACTATGAATA AAAAATAGAA AATGAGGTGC TAAATATTTG GTACAGATTG TAAGTACCTT AACAGAGATT TCTTAATTAA CATTATTCCT TTATAATTGA GGGATTTTGT GGGGTTATTG GGATTTGAAC TCTACAGCAT GGGCTATTAT AGGTTAAAAA TAGTGTTCAG GAGTTTCTGG GGAAGAACTA AAGGTAAGAA GAAAAGAGAT GTTTACAGAA GGGATAGAAT TAACAGCTCT GTGAAATAAT TTTCCCTTAG ACTATGTATA ACTAGTGGAT ATTTAAGAAA AATGAATATA AGTAAAATAG ACTTAGCGAT ATATAAATAT CATAACATAC CACAACAGAG CATTGTCCAC CCCCACAACT TGAAGATGTT

CCATAAGTCC CTCTGGGTGC TCTGACATTT CCATGGAAAT ATCTGCAAAT GAAATACAAA ATTATATTTA GATGTATACT CTTAAACCAC ACATTTATAG CCTTTGAGGT GGTGCTTACA ACTTTCTTAA TAATCAGAAT AAAACACATA TGTCTACTAA CCCTGTCTGA GGTAACAGGT TTCTCAGACA TAGATGAAAA ATTACTTCAA ATTTACATCA GAACTGATGC ACAGTTTTGT TTTGTTCTAT TTTATTTTTA CGCTTTAGTC TCAAGTTGCT AATCGGTACT GCCCTGAATT TTTTCTATGG TTTGGTAATT TTTATACCTG CTTTTCTGCT GAGCTATTAG ATAAAACTAT TTAATATTTA CTATGTATAT TTTTTAAAGT ATTGTTGCTG CTTAATTAAC TATTGATGCT TATATTTAAT GTTATAGCCT CACTCTTGAT CATAATGGGT CAATGCCTCA AATACCTAAA AAAAAAAAAA ATTAGATAGC CAGACACCAG GAAAGAAAAG TATTTCTTTT TTTAATAAAA AGAAATACCT

TTTTGAGCAA CTGAAATGAC AAAGTCACAA ATTTCCTGCA CACCTTAAAA TATACTTAAT GTAAATGACG AGTTAATGGG TGCAGCACAC CAACATGGCA CATGTATACA TGTGTGACAA ACCTGTATGT TGTGCACATG TACCCTAGAA CTTAAAGTAT AATTTTAAAA AAATTCTATC TTCCAAAGCA TATCACTTCT CAGGTAGACA CAGTGTTTAT TGCAAAAGAT CTGATTTCAA TAGTATTTCT TCAAGAGTCT CCCCAGAGAC AAAGTCAAGA AGAGGAAATC AGCATATCTG AGAAGAAAGA TTTCAGGATC ACTTTTTTTG AGGGTCTGAG AAAATGTTTA GTTTCTATAT TATTTAAAAC CAGAATTGAA ATGGGGTGAT TCCTATCCTT GCCACCTGCC TCTACAACCC CAAGAGTTTC TATCTGAGCA TCTAAACGTC TTTTAGGCTG AAAGGCTCAC CATGGCTTTG CTTGGTCCTT CTCTAGTTCT TCTGCAGCCC ATTGAGCCTC TTGACTTAGC ACAAGGGTCT CAGGTCCTTG

CCCAAAGGGA GTGTGCTGTG CTGCAGGTAG ACTGCACTGA ATGTCAACAG AAAGCCTTGC TTTCTTTCAT TTCTCTAACC CAGTCTCACA TCCTCCTCCT CCTCCCCTTT TCCCTCCCCT TCCTCCTGCA CTTCTCTTTC CTCTTTCCCC ACCCCTTTCC TAGACTGGCC TCTATTGCCT CCCACTGAGA CAAAAATGAA CTGCTGATCA GAAAGTAATG TGACTAGATT CTCTCTTCCT TCCCTCCTTT CTATCCTTCC TTCCATTCTC CTATGCATCT TTCCTTACCC TCCTCCTCCT TCACTCATTG TTGTTGCTGT TCTTCTTCCT CTTCTTTTTC CTCCTGCTCC TCTTCTTCTA CTTGTTCTTG TTCTTGTTTT TGTTTGGTTC TTGTTCTCCT CTTCCTCCTT CTCTCTCTCC TCCTCCTCCT TCTTTTCCAC CACCCTCCCC TATCTTTTTC ATAAATGCTA AACTAACTCT TGGCTACCTG TGGTAAATGG CCCTTGGAAA TTGCAAATAC TACAAATCAA AACTGCATTT CAGACATATT

TATGATGTTT GCAAAACTTC AGTAGAGCTA AGCAGTGGAC TTGACTCGTT TCGGTTCCTT CACCTCCGTC TTTCCTTGCT CACCACCTAG TGGACGTCCT TGTTAGTGGC ACTTCCTGAA GTTAACCCCT GAAGAGAGCC CATGCTCTCT AGCTTTTCAC CGTGTAGGTT TGGGAGCCTA CAAGTACCTT TAATATTCTT GGACTATAAA ATGAGATGGT TTTATAAGAC TGCATGTGAA ATTAGGACCC ATATGATGAA GGACAATAAA AAGGAAGACC CACTGATGTG AGTCAATGAG TCAAATGCAA ATCAGATTTG CATTTTTAGG AAAATAATAA TAACAACAAC AAAAACTCTG AAGCTCAGCG CCCCATATTT ATTATATTGT TTAATCTTTA TAACAGCTCT CTGCTATAGA TATGATTATT ATCCCCATTC TAAAGAGTCT CAAAGAGGTT AAGAAACAAA TTCAAAAACT AGCGAAAGAC AAGAAATAAC TAAGATCAGA GCAGAACCAT AGGAGGTAGA GACACGAAAA

AGCCTTCAAA AAATCAATAA ATCCAGGAGC TGCATTTTGA AAAGATTAAC AAAATAGATG GACCACTAGC TAGACTAATA AGAAAGAAGA ATCAATAGAC ACAATAAAAA ATGGTAAAGG GGATATTACC ACTGATCCCG TAGAAATACA AACTACCATC AGAGATTACT ATAAACATCT TTACACAAAT AAACTAGAAA ATCTAGAAGA AATGGATAAA TTCCTGGACA CATACACCCT CCCAAGACTA AACCAGGAAG AAGTCAAATC CCTGAATAGA CTAATAACAA GTTCTGAAAT TAAGGCAGCA ATTAATAGCC TACCAACTAA AAAAAGCCCA GGACCAGATG GATTCACAGC CAAATTCTAC CAGAGGTACA AAGAGGTGCT GGTACCATTC CTTCTGAAAC TATTCCAGAG AATAGAAAAA GAGGAACTCC TCCCTCACTC ATTTTATGAG GCCAGCATCA TCCTGATACT AAAACCTGGC AGAGACACAA CAAAAAAAGA AAATTTCAGG CCAATATCCC TGATGAACAT CATTGCGAAA

ATACTCAATA AAATACGGCA AACTGAATCC AGCAGCACAT CAAAAAGCTT ATCAACCACA ATCAAGTTGG CTTCATCCCT GGAATGCAAG GCTGGTTCAA CATACACAAA TCAATAAACA GAATCCATTA CGTAAACAGA ACCAATCACA AAAACCACGT GATTATCTCA ATAGATGCAG AAAAGGCCTT GGATAAAATT CAACACCCCT TCATGCTAAA AACTCTCAAT AAACTAGGTA TTGATGGAAC GTATCTCAAA ATAATAAGAG CTATTTATGA CAAACCCACA GCCAATAGCA TACTGAATGG GCAAAAACTG AAAGCGTTCC CTTTAAAAAC TGGCACAAGA CAAGTATGCC TCTCTCACCA CTCCTGTTCA ACATAGTATT GGAAGTTCTG GCCAGGGCAA TCAGGCAAGA GAAAGAAATA AAGTGTATTC AAATAGAAGA GAGGAAGTCA AATTGTGTCT GTTTGCAGAT GACATGATTG TATATTTAGA AAATCCCATT GTCTCAGCCC AAAATCTCCT TAAACTGATC AGCAACTTCA

GCAAAGTCTC AGGTTACAAA ATCAATGTGA AAAAATCACA AGAATTCCTA TACAGCAATA ATAGACAAAC AGAGAGCCAA ATCATGAGTG AACTCCCATT CACGATTGCT ACAAAGAGAA TAAAATACCT AGGAATCCAA CTTACAAGGA ATGTGAAGGA CCTATTCAAG GAGAACTACA AACCACTGCT CAAGGAAATA AGAGAGGACA CAAATGAATG GAAAAACATT CCATGCTCAT GGGTAGGAAG AATCAATATC ATGAAAATGA CCATACTGCC CAAGGTAATT TATAGATTCA GTGCTATCCC CATCAAGCTA CTACTGACTT TTTTCACAGA ATTAGAAAAA AACTACTTTA AATTTCATAT GGAACCAAAA AAGAGCTTGT ATAGCCAAGA CAATCCTAAG CAAAAAGAAC AAAGCTGGAG GCATCATGCT ACCTGACTTC AAACTATACT ACAAGGCTAT AGTAACCAAA ACAGCATGGT GCTGGTACAA AAACAGATAT ATGGACCAAC GGAACAGAAC AGAGGCATCA

GAAATAACAC CACACATCTA CAACCATCTG ATCTTTGACA AAGCTGACAA AAAGAAGCAA TTGGGAAAGG ATTCCCCATT TAATAAATGA TGTTGGGAAA ACTGGCTAGC CATATGCAGA AAACTGAAAC TGGATCCCTT CCTTACACCT TATATAAAAA TTAACTCAAG ATGGATTAAA GACTTAAATG GAAGACCTAA AACCATAAAA ATTCTAGGAG AAAACCTAGG CAATACCATT CAGGACGTAG GTATGGGCAA AGACTTCATG ACTAAAACAC CAAAAGCAAC AGCAACAAAA GCCAAAATTG ACAAATGGGA TCTAATTAAA CTAAAGAGCT TCTGCACAGT AGAAAAAAAA AAACTATCAT CAAAGTGAAC AGGAAACCTA CAGAATGGGA GAAAATTTTT GCAATCTATT CACCTGACAA AGGGCTAATA TCCAAAATCT ACAAGAAACT TAAACAAATT TACAAGAAAA AACAAACAAC ACCATCAAAA AGTGAGTGAA GGATATGAAC AGATGCTTCT

CAAAAGAAGA AGTTTATGCA GTCAACAAAC ATATGAAAAA AAGCTCATCA TCACTGGTCA TTAGAGAAAT GCAAATCAAA ACCACAATGA GATGCCATCT CATGCCAGTT AGAATGGCGA TTATTAAAAA GTCAGGAAAC AACAGATGCT GGAGAGGATG TGGAGAAATA AGAATGCTTT TTACAGTGTT GGTGGAAGTG TAAATTAGTT CAATCATTGT GGAAGACAAT GTGGCGATTT CTCAAGGATC TATAACTAGA AAAACCATTT GACCCAGCAA TCCCATTACT GGGTATATAC CCAAAGGATT ATAAATCATT CTACGATAAA GACACATGCA CACTTATGTT TATTGAGGCA CTATTCACAA CAGCAAAGAG TTGGAACCAA CCCAAATGCC CACCAATGAT AAACTGGATA AAGATGATGT GGCACATATA CATCATGGAA TACTATACAG CCATAAAAAA GGATGAGTTC ATGTCCTTTG CAGGGACATG GATGAAGCTG GAAACCGTCA TTCTCAGCAA ACTAACACTG GAACAGAAAA

CCAAACATTA CCCATTCTCA CTCATAAGTG GGAGTTGAAC AATGAGAACA CATGGACACA GGGAGGGGAA CATCACACAC TGGGGCATGT CAGGGGATGT GGGGCTAGGG GAGGAACAGC ATTAGGAGAA ATACCTAATG TAGATGACAG GTTGATGAAT GCAGCAAACC ACCATGGCAC ATGTATACCT ATGTAACAAA CCTGCACGTT CTGCTCATGT ATCCCAGAAA TTAAAGTATA ATTTAAAAAA AGTTTAAAAA AAGAAAGTTG CCTTAGTCAC ATAACTAGTA AGAGACATGG TTGGGAATTT GAACAGAGGC CAATCAGTTC CAAATCCATG CTCTTGATCA TTAAGCTGAA CTTATGGCAG GAACTTGGAA GACATGGTAA AATGGGGAAA AACGTGGAGC CAGGGAGACT TGTGAAAGTG CCAGTGCTCC CACTATACCC TGAAAGAAGT ATCTAGACTT ACTTTTTTCT AAGTCCTCTC CTCTAATTCT CTCAATCTCT CTCTCTCTTT CTCTAAGAGA TGGGAATGCT

GCTCTGTCAC TCAGGCTAGA GTGCAGTGGT GCGATCATAG CTCATTGCAC TCAAGGAATC CTAGGGTCTA GTGCCCCTTC TCCCTCAGCC TCCCATGTAG CTAAGACTAC AGGCACATGC CCCAACCCTC GACTAATTTT TTTATTTTTT ATTTTTGTAG AGACAGGATC TCACTATGTT GCTCAGGCTG TAATTCTGTC TTGAAGCTTG TCCAATCAGG CTTTCAGCCA CACCAATTCC CTGAGACTGC TCTCACCAAG GTCCTACACT TCACTAACAC AAACAGCCTA TTCTCCATCC TCATCTTACT TCACCAGGGA GCTCCTGGTT TTCCTCCTAC TTCACTGGCT ATTTCTTCTG TATCATGTGT TGATTCTCCC TCATCTCCCC AACCTCCAAA CCCTTGGAGT ACTCCAGAGA TCACCGCTTT GCTCTTCTGT GTCTAACCTC ACTAACTTGG TGGTCCAATT CACACTCTTG ACTTTGAATA CCATTTAAAT GCGAACGAAT TCTAAATTCT GTACAACCAG AACCATTCTC CTGTAGCCAA ATGCCTACTC AACATCTCCA TCCCCAAACA AATTTAGTTG TTCAATAAGC CTCTCATATT TTACATATCC CAAACTGAAC TTCTGAATTT CTCCTCCAAT CTGTAGGGCT CTTCCCACAG CCTTTCCATC TCAGTGGATT ATAACTCCAT CCTTCCAGTT ACTCAGACCA AAACTTTTGG AGTTAACTGA GACACCTCTC TTTTTTTTCA CAAGTCATAT CCAATGTGTC AACAAATTTT GGTAGTGGAA ATATTGCGGG ATTTTTTAAG AAATCAGAGA GACCGATGGG GTTCAGGAGG ATATTTATTA TTTAGGTGCA CTGGCCAAGT CAGATTAACA TCCAAAGGAC TGAGCCCTGA ACAAAGAGTT AAGTTACCTT TTAAGCATTT TGTGGGGTGG GAGAGAGGGG TATCTGTGCA GGGGGAAGCA TACTACAGAA

GTGAGAAATA AAGACAGTTA TTCAATTAAT TGAGACATGC ATTACATCAT TTCTTACTTT TCAAGAAGAA ACATGTTTTG CGACTTGAGT TTATCTGTCT AGTGACCTTG CAGCTGCACA GCTAGAGAAA CAGGGTCTTC ACAATGCCTG GGAAAGGAGG AGAGGTAAGT CTCACTAGCC ACAGAAAAAC AGGCAGTTAA TTTTTAAAGG GCTCCAGCTC TTTCTCTTTC TCAGGGGGAG TTGGGTTTTG TTACATACAA CTGAGTTTCC GCTTACACAT TATTTAATTT CTTTTAATTC CTGTTCCAAA AGAAGCCAGA TACAAAAGGT TACATGTTGT CTGATTCCAT TTATATGAAA CATATAGAAG AGGTAAATCC ATAGAGACAG AAAGTAGATT AGAGGTTCCC AGGGGCTGAG GAAGAAATGG GGACTAACTG CTTATAGGGT ACAGAGTTTT CTTCTGATAA AAATATTTTG GAACTAGATA GACATTTTGT TAGGCCATTC TTGCATTGTT ATAAAGAATT ACCTGAGACT TGGTAATTTA

TAAAGAAAAG ATGTTTAATT GGCTTACACT TCTGCAAGCT TTACAGGAAG CATGGTGCCG ATATCTGCTC AGCTTCTGGT AAGGCCTCAG GAAGCTTACA ATCATGGCAG AAGGTGAAAG GGGAGCAGGC ATATCACATA GCAAAAGCAG GAGCAAGAGA GGGATGTGGG GAGGTGACAG TCACTTTTAA ACAGCCAGAT CTTGTGAGAA CTCATTCACT ATCATGAAGA CAGTACCAAG AGGATGGTAC TAAATCATTC ATGAGAAACC CCACCCTCAT GATCAAATCA CCTCCCACCA GGCCCCACCT CCAACACTGG GGATTACAAT TTGACATGAG ATTTGAGTGA GAACACGGAT CCAAACCATA TCAGAGATGG TGGTTATACA ATGCGATAAA CGTCACTGGA TTGTACACTT TAAGATGGTT GTTTTATGTT GTGTGAACTT CACCTCAATA AAAAAAAATA TTTAATGTAC ATTCAGCCAA AAGAAGATTT GGAATAGGAA AGGTCATGGA GATATATTAA CAGCCATTTG

ATGGGTGGTA AGGAAAAGAG TGGTTATTAG ACTGTTTTGT GGCCCTCAAA AGGTAGAACT AGATCGAGTT GGTGAGCATT ATAAAACCAT CACAAAACCC TGGAGAGAGG ACCCAGTGCT GAAGAACCGT TTGCCTGCCA TGAGACATGA GGGAAGTACC AGTGAATGCC ATTGAAAGCA GCATCCCTGG GTCCAAGGGA TGGTCAAAGG ACCACTACCC AACCCTTCCC TAGCCTACGC CTCCATTACA GATGACCGCA AGATTTATTT GCTCATTGCT GCCAACCAAG GCTGCACTCA CTGCAGTTGC TATCAGTTTA TCATGGGTAA AAGGAATGTG CAGTAGAGAA CTAACTAACT GCCCACCTAC CTCCACAATC CTATCAGGAC AAATCACCAT GGCTCACATT TCCTTACATT TGGCATGTAA GCCCCTCTTA CTGTCTGTCA TCTATCTCCT ACACAGTTCA CCTAAACTGT TCTCTCCTGA CCCAACCTTG ATTTTCATCG CAAATGCTTC CTTGCCATCT CTGGGATTCC TGTCTTCACC

ATCACCAAAC TCCCCTCAAT CTTCCAGTTT CCTGTTCAAA CTTTTCTCCT ACCTCCTTGC TTTGTCATTA GCCCGACTGC CTCCCTAGGA CATCACTTCC CCTGCAGATC TCTCAAGATG ACAATATTTA TTCTCCACAC AGCACATACT TCAGGGTTGG AAGGCAGGGG CAATCTTCTC CTTTATAATG AGTGCCTCTT ATATATGTTT ATTCATCTGC CCTCTTGTAA AACACACACA CACACACACA CAAAGAAGAA ATAAAATAAC TCTGCTTCTT TGAAGCTTGT GACACTGAGA TAAACCATCT CACTGTCCTC ATTGTAGTGA CCTCTCAACT CCTCATGCAA GATTGGCTTT GGCACCTAGT TCCTGATCTT CCTTTCCCTG TAAGCACTTC TCATAGTCTT ACGGGACTTC ACCATCCATG GCACAACCAA TACCACAGCC CAGATCCTCA GCTCTCCAAT GACATTTTCC TCCACTAGAC TTGAGCTACC TCCTTCCCTA GGCACAGCCT CAACCTCGAC AACACCTAAG ACTGTACCGT

CTCTAAAGTC ACATGTTCAA ACACTTCACT CTTTAACCAC TGTCTCCTAT TCTTGCAAGT GTATTGCTCA AGTATCTCAT TGCAATGCTT TTTACTTCTA CCTCATTGAA CCTCCAGGCC ATTAAACATT TCCTTATTTC TAACCATCAG GTTTCTCCTT ACTTGTTTGT TTGTTTATTT GTTTCTTTTT TTTTTTTTTT TTTGAGACAG GGTCTCACTC TGTTGCCCAG GCTGGAGTGC AGTGGTATGA TCTCGGCTCA CTGCAGCCTC CATCTCCCTG GTTCAAGTGA TTCTCATGTC TCAGCCTCCC GAGTAGCTGG GACTACAGGT GCATGCCACT ACGCCTGGCT AAGATTTTGT ATTTTTATTA GAGAAGGGGT TTTGCCATGT TGGCCAAGCT GGTCTCGAAC TCCTAACCTC AGGTGATCCA CCTGCCTCAG CCTCCCAAAG TGCTGAGATT ATAGGCATGA GCCACTATGC CCCACCTGGT TTCTCCTTAT TTATTTCAAG TCTATGCTGC ACTATTAAAA CTGCCTTGAC AAAAATTATA

ATAGTGAGAA AATTATGACA GTGAAAGAGA TCTGAAATAA TCAACCCCCA TCTTGCCTTT ACCTTCCAGA CTGCCCTTAA TAATTCCTGA GCTTGGGCCA AGCTATCTTT GGCAGAAATT TAGTTTATAG TTTAAATGAT AATAGCGCTT CTCCAAAACT AAACTGCCTT TGTAAAACTA ATAAAAGACC ACCAATGAAA GGTTAGGAGG ATGAGAGGAG CCTGAATTCT GCTAAGGTGT AGATGTAAAC AATTACCAAC TGTTATTCCG GAGGTCACAA GATTTGCAAC ATCGCCAATT ACTCCTGCAG ATAACAGCAC TATCATAGAA TCTGATTGGC CTTTTGAGAT GTCTTTTCAG ATTCTTACAT TTCAACTGGT GGCTCTACCT GGACCCATCA ACAAGTCCTG TGGCTCCACC CAGAAGCAGA CTTAACATGC ACAAGGACCA TTTTCCACAC CGCTATGATT GCATCCCAAC CAATCAGCAG CAACCATTCC TCTGCCTGCC AAATTATCCT TGAAAAATCT TAGCCTTAGA ATTTTGGGGG

AGGCTGATTT CAGTAATAAC AAAACCCCGG TCTCCCATTT GGCTGGCTCT GCATGAATTA AATTCTTTCT CTATTGCAGT TCCCATCTTG ATAAATCACC TTTATCTGGG CAGCAAACAA AAGGAACCCA TTGGACAGTT ACACTGTTGG CAGATATATC TTGCTTCCAA AATTGGATTT TTGTTTAATG AATTTATTCT GTTTTCTTGA TATTTACAAC TGTGAATGTT GTGTCTGAAT TCTCTTTATT TCTTGTTGAA AAGAACTATA TTGCTACAGC CAGTACATAC AGATGGATAG CTAATTACTC AACACGGGGG GATGTGACCA TCAGCGCACT GTGCAAATGA ATGTTACCCA TTGTCCACTT TTCCCAAACT ACATAGTGTT ATATGGTATA TGACCCAATC AACGGTGGCA AAGCTCCAGA AATACCACAT AGACATCAGG GACACTTTAA ACTAATCAGC CTATAGTCCT TTTTCAGTAA TTTCCAAACC TOGTTGTGCA TCCAAATCAC TTGGTAACAT TAAAAAAACA AAAAAATATA

CACGCAACAT TCGCTCCCAA TCCTACTGAA TCAGAATATT TTGGGTTGGT TCAGGAACAT TCAGGAGTTT TTCAGGGTCC AAGGTTTATA TAATTTGAGG TCTCTCTTTG AGAAAAGGAA CGTAAAAGCG TCTTGCTTTT ATAGATCTTA CAAAGATGTA TTACCATGTA AACACATTCC TAGGACCCAG GCCCTTGTAA TTTAAAGGTT TATCTAAGTA ATGGGCCCTG AAGCTTAATT TTCATTATCT TCAGGGCAAA TTACCTGTGG GTTAGGGTTT AGGAATATAT CTCTCTGTGT ATGTGTGTGC ACATTAGCAT GTACGCTTGT GTGGATTTTT χχ_Tχχχχχχχ x TXXTxxc TGAGACAGAG TCTCGCTCTG TCGCCAGGCT GGAGTGCAGT GGCGTGATCT CTGCTCACTG CAAACTCCGC CTCCCAGGCT CAAGCGATTC TTCTGCCTCA GCCTCTTGAG TAGCTGGGAC TATAGGCACG CACCACTATG CCCAGCTAAT TTTTGTATTT TTAGTAGAGT TGGGGTTTCG CCATGTTGGC

CAGGATGGTC TTGATCTCTT GACCTCGTGA TCCACCCGCC TCCACCTCCC AAAGTGCTGG GATTACAGGC GTGAGTCACC ATGCCCAGCA CTTGTGTGGA TGTTTTAAGC TCCCAGGTGA GTGAATACAA AACTAGATCT TTCCCTTCTG TAGCATCTGT ACTGTTTACT CTATGCATCT CAATATTTTT TCTTTTAGTA TCTTTCCTTT TTCTCTCTTA TTACTTCCTC TTGTGCTATT TTTACACCTC CTTTTTTAAA AAATTTTTTC CCTTTTATTT CTATTGACCT TTAGCCCTCA CAATGATTCC TACAAGCCCC ATTTCTGTAA ATGGGGATTG AAATAATTGC TGGACTTTTG AGAGATAGAT ATATT AATT GCAAACTGGC AGTAGTGGGG GCAGTTGATA CATAACTAGG TTTTAAAGTC TAGCCTTCTG AGACCACTCA TTCCATTTGT GAAAAGTGAT TCTACTTCTT ATTATGAGCC AAAATATGCA TTCATTCACC CATGCATTGA TTTATTCATT CAATAAATAT TTGTTGGATG

TCCACTCTGT ATCAGGAATG TGCTAGGTTC TGGGAATACA GCAATGAACA AGGTAATTTT TCCCTACCCC TAAGGAACTT AGAGTTTAGT GGGGAAGACA GACATTAAAC AAACAATTGT GCAAGTAATA ATCTATAATT ATTTATTACA ATTAAAGGAA GGAAGAGACA TATGGATTAT GAGGGCATTA AAGAGGAGAC CTAGTGTAAG TAGCCAGTTC TCGTGAAGGG ACATGTATTA GTTGGAGTTC TCCAGAGAAA CAGAACCAAT GGTGTGTGTG TGTGTGTGTG CGTGTGTGCG TGTGTGTGTT GGGGTGTGGG GGTGTGGTAT TTTTTATAGA AATTGTCTCA CACAATTATG GAAGCTGAGA AGTCCCATGG CCTGCTGTCT ACGAGCTGAG AACCAGGAAA GCCAGTGGAA TACTTCAAAG TCCAAAGGCC CTGGAACCAA GAGTGCCAGT GTTGGAAGGC AGGAGAAGAT GGGTGTCCCA GCTTAAAAAG ACAGTGAATT CACTCTTTTT GCTCTACATA GGGCCTCAAT GGGTTGGATC

ATGGCCACCC ACATTGGTGA AGGCAATCCT CTTAGTCTAC CAATTAAATA CTAATCTCTT TGGAAATACT CTCACAGACA CACTGAGAAA TAATGTTTTA TCAGGGTGAT AGAAATCTTC TGGAGTTAAA CAATGGTGAT AGCTGTACAA TCACATACAT TTTTAAAGGG TGCGTTTTAT GGAAAGTGAG TTTTATCTAA ATAAAATTTC TAAGAAAGAG ACTTAACACA GAGATAAACA TAAGCACATT TATTGTCAAC CTTTATAGTG TTATGTCAAA TAGGTCTGAC ATAAGCTTAA ATAAATATAT ACTTTAAAAA TTATAAAATA TTTTAAGTTA TAATTTAAAA TTCTCAATAA AACTCAAACA CAAACCACAC TGGTATTTCA CACAGCTAAT TTCTAATGCA GTTTACATAA ATATTTACAA CACTTAAACA ATTTCAAAGA AAATAACACT GTATTCCATA CATAGCCTGA TCACAGTAGT TGTTCTCTCT TATTTCCCAG AGTTTTTCTG CCCCTTTAAA AGAACCTCTG CTGTTCTGAT

CCTTATCACA TCTCTGTTTT GACTGTTGGC TTTGTTGTTG CCAGTGTTCA GCCAGAACTT CTCTGAAACT TTTTTTTCAA CACATGCTAA GTTAATGGAA GTGTAGGAGA GTTTTGATTC TCACACTCCT CAAGGCTAGA GCAGCTTTGG CAATTACTGA CTGAGAATTT TTCATTGCCA GTGATCAACT GAAAACTGGA GATTCCTTTG GAATTGTTAA ATCTGCTTAT AAATAAACAT AAATGCTTGC TCACACAGGC ATTCCTCTCT TCCAGAGCAC CCTAACATAC AGAAGAAAAC AAATAGGGAA TAACTATTAG ACATCTTCAT TCGTTAAAAA TCTACCAGAT GACTCTTTTA CATGGTGAGT TTCTATTGTG AATTTAAAAT CTTCCATAAT ATACAAGAAT TATGTTTACA TATCATATCT GACAAACATC TTTGTAGGAA TGCAAAGCAG ATCCATCTTT CTGTATTCTT TTCCAACAAA GACATTCATA AAATTATACC TTTGTGTGTT TGCATTTATG CTTTTATTAG TTCAAAACGT

TTGGCCTCAT GGAAGTTTTT CATCGTGGAA ACCACATATT TCTGAAAAAA TATCTGACAA TATACAAACC TTCCATTCAG TTTTTACTCT CCAATTCTAC CATGTTTTCA AAAAACAACT GTAGTAAAAA CACTCAGAAC TTTATTCTGG TTAACATCAT GCCTTGCTAG GGGACAATAG TTTCCCTTTT TGAAATAAAT TTAAAACAGA TGTAACATAA TTTGTTAATA AACAATGAGG GGGTAATCTA GAATAAGTAA CTTTTACCAT ATCATAGTTG ACAGCATTTA CAAGTTTTTT AAGTCCCTAC CACACTTGTA TTGAATGAAG AAGTATGGAA GATTATAATA TATTCAATGC AAGTAAAAAT ATCACAATCC TTAAGAACTC TTTAAGAAGC ACTGAATCCC ATAGGGATGA AAGTGATTAA ATTGTGCATA GTAACCCTCG CACAGAGCAT TCAGTAGGAT TTGCACCATT AACAACCCTC CATGCATTTG CCTGTGGGCA TTCAACATCT GTCATTTTTT TAAGTTATAA TATTTTTAGT

CATTTTTTTC CTCTAAACTC TGGATAATTA TTATTCATTC TTATGACAGC AACTGTGTAA TCAGCTGTCG AAACACTGTG AAGGGCAAAA GAAAGAAAGC CACAAAATAT TGTGTTTCTG TGCCAAGATT TTACAGCGAG CAAGGGAGAG TTAGAAAAGG AATTCTGAGA TTTCAGAGTC TTGGTCTCTT CACCTTTGCT TGGAAGAAAA TATCCTTTCC CTTCATTAGC CAACACTTTC TTGATCCTGA GAGTAGGAAA GGGAACACTG AGTCTTTTCA GTTGAAGGCC GTCCTTGCCT GCTGGACTTT GATCTATTGA AGTGGTGATG GGTGTTGCGG TTTCAGCCAT AAAGGCATCT GGCATAGTAG GCAAGAAGGG CCAGAGACCC GAGGAGAGTT ATCTGTCTCT GTTAACTTCA GTGTATCCCT CTAGTTCCCC AGATGCACCT GTTTCTGTAA ATATAAACAT GCATGTCATC AGAACACTTA ATATTCTGCA TACTGATCAT GACAACAAAA TGTACCTTCT AACACAGACA CTCTCACTAG

GATAGACCAT GTAGGAACAT CGAATTCTAT TCAGTTAGGA CAGTGATGAT GTCTACATAT TATACCTCTG TCAAAACCTA CAGAATATAC AACACAGCAC AGAGTGAATT CTAATGTAGC CTGTGGACAT TAATGAATAA TAATGTATCA ATATTGGCCC ATCAGTTGTA ACACTAATAT AAGATGTTAA TAACAGGGGG AATTGAAGGG GTGGTGGGGA GATATGTTGG AACTCTTTGT GCTTTCTGCT CAATTTTTCT GTAAACTTAA AACCGCACAC ACAAAAAAAG TTATTTTAAT TTTTTAAAAA GTATTCAGAG GGACTTGACC TTTCCAAATT CTCTCAAAGC AGGTCGGAGT AGTTAAGAAC ACAAATTTTA GAACCAGACT GCCAGAGTTT GAATCCTGGC TACACCACTT ACTAGCTTTG AGATTTCAGA CAATTTACTT AACTTCTCTG TCTCATTTTC TTCATCTGTG TGATAAGAAA TAAAGTAACA GGCCAGGCCC AGTGGCTCAC GCCTGTAATC CCAGCACTTT GAGAGGCCAA

GGCGGGTGGA TCAGGAGTTC AAGATCAGCC TGGCCAACAT GACGAAAAAA TACAAAATCT CTACTAAAAA TACAAAAATT AGCTGGGTGT GGTGGCAGGC ACCTGTAATC CCAGCTACTC AGGAGGCTGA GGCAGGAGAA TTGCTTGAAC GCAGGAGGTG GAGGTTGCAG TGAGCCAAGA TCATGCCACT GCACTCCAGT CTAGGCAACA GAATGAGACT CCATCTCAAA ATTAAAAAAA AAAAAAGTAA AAAGAAAAGA TAAGAAATAT AGTACCAGCC CCTATCTCAG AGTTCCTAGC TTAGAAAAAT TCCCAGAATA TAATAAGTGC AATGTAAGGG TCAGCTATCT TCATTATTAT TATCTATCAT AAATGAAATT ACACAATAAA GCTAGATCCG TTTCTTTCCT CTCCTTCTAC AAAAAATAAA GCAACTTTCC AGAACAATAC CCAGGTGATG ATTTCTCCCC TGCTCCCTCC CTAAGATATT GGCAAGTTTG GAGGGTTCAA GGAGAAACAG AGCATGTAGA GAAGATACCT

CTCTCATAAC CATTTGTGAT TTACAAGTCT TACCTGATTC TTTTGAACTT AAAGGATGTA AGAAGGCTTT TGGTAGCTTC CATCTGATTC AAGGCTTTGG CAGCTGCTGT GGAATACATG AGAACACTAG GTAAAGCACT GTCTTCCAAC ATGAAGAGAG AAAAATATGT GGAATGTTCA ATGGCATGCT TTGTATAAGA ATGCAACTTA CCTGGCAGGA ACAAATTTCT TTGCTGCAAA AGAAAAGACA AACAACCATT AATTCAGACT AAATGACTTT TAAGGATATA TTAAATCCAG ATACAATATG ACTTAATTCA TCAAGTGTTG CAAACTCGAT GCTTCAGGGC CTCTGTAATA ATCAGAGCAC AAGCATGGCT CTGTGGCATC TAGGGTAAAA TGCAAAGTGC ACAGCCATCC AAAGGGCATA GCAGCTTCCT AATGCCAGCA AATAGCTACG GGGTCATCTT GCCCAATTCA GCTCCCAATT TTTCATGAGA AGTCCAAAGT CTTAATTTAA ATGTGAGATT TCCTATTTTG TAAACGTCAG

AACTTAACTC AAAAATGTTT TAAGTACTCT TAAACATGTA AGCCAAACAA ACCATGAGTG TAGTCAGATG TGCTTCCATA TTCCTTATGA GAGACTCTCA AATTTAAGCC TGTACTCCAA ATAAATCTCC TTAGGAAGAA TTTTATCCAT TTTCCTTAGA GTGCTCATCA TGGCAGTTCC ATTGCACAAT TCCGGGAGGC ATCATATAAT TCAACATGAA TAGCACCCCC TGGAGTTGTA CAATATTAGG CACGACTAAC ATTTTTATTT CCTGAAACAC TTCCCACACT GAGTTGTACT ACTAACTCTT TTCTTAATAC TTCTGCTTAA TTATACTGCA TTTTATCCAG ATTCTAATTA TTGTTTAAAT CAGTAAGCAA GACCATGACT TATCAATGAG AAAGAAATGT ATTTTCAAAA ACATTTTTGA AGTACATTCA TAAACTTCCT CACCTTTCCG TAAGCATTTC CGAAGCCAGA GGAGAAATGG TGCTAATGTC AGGAGGGAGA GTCCAGCAGC AGAAAGTCCA GCTACCAAGG GAATGTTGGA

CTCAGTGGGA GCTAAGGAAG TAAGAGACGA AGAAAGGTCA TGAGGAAGAA TTGATGTTAA AGTCTCTCCG TCCTGTCCCT TTGGCCTTTT TTCTGTACAT TCATTACTAG GAGCAGAAGA GCTATCTAGT TTAATACAAG AAGCAGAGAT GTGGCATTAC AGGCCTTTGA GATCTGCTCC AAGCCACCTT TGAAGCTATT TCCACCATTG GCAGGCAGAA CTCTAACTTG CCAAGCTCGT TCACAATACC ACACCACACC TTGGTTAATA AACACTGCAC TTGCTTGCTC TCTTGCTCTC ACTCCCTCTT GTTTTCCATT TCCCCTTTCT CCTCTCCTCT CTCTGTCTCC TTTTTCCAGT TGTCAGAATT CTACCCTTTC CATCAACATG CAACTTCTGT TTTTTCTCTA TCCCCATACA ACTTAATATT CACAACTTGT CAACCTGGGC GAACTTTCTG GTTTGGATAT AATGAATAGT TGATTACTGT AACAAGATAG CTCCCCCTTT TTCTTTTTAA TCACCAGACA ACCACCATCA ATCAATGCAT CACCTTCACA GGTAGGTAGC AGGCCAGACC AGTGTCCTGT GGCTCCACAT GTCCGAGCTG CAGAGCCATT GAGCGTCCAT CCTTCAGGAC AGGCGAACTT GCACACAGTG CCAAACACGG GCTCCCCACT GCAGCTCATG TTGATCTTTC CCGGAACTGC CAGGCTTGAA CATTTTACCA CTGCAAATGT TAGGTACACA GGCAGAGTTT CAGAAAAATC TACTGGAAAA CTTCCAAAAC TTGCTTAAAA GTCAACAATG AATGTAAAGT GTAAGCGCTA CTTAGTTTTC AGCATGTAGG AAATTAGGAC CAAACCCCTT TGGGGCAATC TAGGTTCAGA AACTTTATGA AGTATTTGAC CTGTACCCTA AAAAAGTCTG CACTCAATTC TACCTTGGCA GGAAGGAACC TCTTCTGTCC ATTGTCCCTG AGATGTGCAC

TCAAGTTGAG TTGATCCATG TAATTCAAAT CCCTCCTCAC AGCTGAAGGC ACAAGAGGAC TTGTAGGTGA ATTCTCCAAT AGGGGAATGA GCACACCTCA CCAAACCCTT CGGGGGCTGG TGGACAGCAT CGCATCTCAC AGCTGGAACA CACGAGAGAG CACTTTAGAA GTTTGTTTGC ATCTCCAGCA ATACGTTTCC CAAGGTAACC AAGTTCCCAA GCTCTTCAAT AGTTCTTTTT ATCTTAAAAT AAAATAAAAA CAAAGACTGT ACCTTCACAT GTGGGCTTCT CGTTGTCCCA CTCCCCTGTG GGGCCACATT GGAGCCTTTT GGATCCCTTC AACACAAAAC CCTGCTCACA GGAGAACTCA CAGCTGGACC CATAACGGAA ACTGCCAGAA GCACTAGGAA GACAATTCAT GTAGCCTCGC TCGGGGTTGG ACAAGGCTGT GCACTGGAAA GCTGAGACAT CAAAATGATG GTCAGAAAAT ATTGCAGTGG AACTAGAGAG TACTTGGCGT TTGTTGAGTG AACCCAGTTC ATTCAAGCAA

CACTTGGAGA ACTGAAGATT CTTTATAATT CCCTGGACAA ATGGGAAGAT GGCTGTGTTT TCTTTGAATT TCAGCCCCCT CACTGATCAT GGCACTAATT AAAAGACTAA TTAATCAGAA CATTAGTTCC TGAGCACTGT TCTTCTAACA CACAAAATAA ATTATGGTCC AAGGAAAGAT TTCACGCAGT CTGAGGACAA CATATGGGTC ATGGATGTTT ATAGATGGTG CCAAAAAGAA AGAAAAGAAA GCACCCCTAT AAAATTTGTC TGTTTTGCAG TTTGGTTTTT GTGTTATGTT TTGCTACTGG AAATCATTCT GTGCTGGCTT TGGCTAGGAC AAGGCCAGTG CCTGATAGTA AAAACTGCTT GTTTTCAATA TCCTTGCTCT CACTTTAAAG TGAATTAAAA TTTACTGCTT ATATATGCAT CAATACTATC TCTGTAGCTG ACACCATGCT TGAAACAGTC TCATCACTGC TAATTATGAG CCATTTCAGA AGACAGGTGT GATGAGAGTT TTACATTCAA ATCATGTTCT CATTATTCTG

CTTTCCGAAT TTTCTAATAT GATTCCTTTA GATTAAGAAT TCTGTCTATT CCATGCTAAT GTCTACAAAG TTTTATCAGC ACATCACAGT TAAAAAAAAA CAGCAAAGAA TTCATTCTTA ACACATATGA TCCTTTCCCT GGCCAAACAT TAGTTCTTTT AAATGAATCT CAAAGATACG AGGGTTGCTC ATCAAATCTG ATTTCTATAG TTAAAGTGGG TATTGGTTTT TTTTTTCACT GTCCAAGTTT GAAGATGGTT GTTCTTTAAG AAAGTATAAA TCGAAGGATC TCAAGCTTAC CTTCACAAAC TGGGATTTGC TGTGTCCACT GCCCTTGAGT GGTGCATTCA ACCTGGGCTG GTCCCTGCAA CATGAAGCCT TCCTCACAGG TGAAGTTGCA GGATGATTTG AAGGTGAACT CTCCAGCAGG GGAATGGCTG CACCTCACAG AGCCATTCTG AGGCTGGCGG ACGGCCCTGC ATGTCACAGC TGTAACAAAT ATACGCATTG ATATTAGCAC GGCCTAGAAT TAGCTTGCCC ATTTCCAGTA

TGGGTTGAGA GAAAGAATGT TCACAGTAAG TCTCCATGTG GAACAACTCT ACCTTTACAC GTTGGCTTCT CGTTGTCCCA ATTCCCAGAT GAGGTACACT GAAGGCTCTG GGCTCCCATT AGTTCAAATC CTTCTTCACA GTCAAATGTA CAGGTTGTGT TCCATGGGAA GCTTCCAGGG TTTTGGAAAC ATTCCACGAA CCCATTGGCT GGATTTGTCA CAGCATCACA CTCAACCACT GAGGATTTTA AAGAGCACCA TGAATTTTAC AGAAGAATGA TCTTTTCACT TCCTATTGAG CTGGGTGCCT AACAGAGTGA GGAAGCTGCC TTCAAAGGGT AGATCCCAAA GTCCTATGTC AATTCTTAGG GACATGCACA GCCAGAATAA AAGCTTTTAT TCTTTTTCAT GGATATTCTA TCTTTTCTGA TTTCCACTTT GCCTATGCTG AGTGGTCTCT AATCT ATGTT ATCATTTACG TGAGGTAAAA ATTTAAAAAA AATAGATTCC AGATTAGGAG TTATGACTAG TACTGACATA CGTAGGCTAT

TCATTTATTT TAGCCCATCA GAGCCTGAAG AACTGATTTT TCTTTTTTTG GCCTCTGGTT CAGAAAGATA AAATTAAGAG AGAAAAAGAG ATACTAAGAC TGCTTGACTA TCATGGTCTT AAGTTAGTCC CATGGCTTGG AAAAGTTAAA CAGGGAAACA AGATGAGAAA TCCATTGAGA TTTCTAGAGC TTTATTGTTT TATGGTCTCC CTTACAAATC ACCAGAGCCT CAGAAACACC CATTTCAAGC ATAGAATAAA AAAACCTCTC TCAACCCAAG CAGGTACTGG GTTGGCAATA TACATTGGCT GAGAGAACAA ATTGTATTAA AAACAAAAAC AAAAAAAAAA CTTTCCCTGA AGTTTTGAAA ATGTAAGTTG AATCAAAAAA CAGAAGCAAT GAGGGATGAG TTACAGAACG TTCTGTGCAT TCTCAGAGGG ATTTACCATT GCAGGCTGGA ATAGGAGCAC TCCATTCTCC AGAGGACATA CACTGCATGG TCTCCATGCT GCTTGGCAGG TAACCCCTAT CACAGCTGAT AGAGCAGGAA

GAATTGTAGC TGAAGTTTCC CAGTGGGTGA CTGCAAACCA GGCTTCCATG CTCAGGGGAT TCCAGGGCTG TACAGTTCAC AACTGAAAAA GAAACCCAAA TCAGTTCTGC TCATCTCTCA CCTTTAACAG ATAAGAACAC TGGAAACTAG AACTACAGTT TGGTTTTTTT TTTTTTTAGT TTAAAAATTT ATAAAATTTC TAATGGAATT TGTAAAATTG ACTGTAATTC TACCCCTTTT CTTTTATTCA AGAAAATGCT GATCCATAAC AACAACAACA AAAAAGCAGT GATGACAACC ATAAAAAAGA AATATTGAGT GATATGGGGA GAGTAGTGTA ATTGTGTTTA CCTCAAAACT GTTCAAATTA TATGAACAAA CACAGCAAAC TTAGGTACCA CAACAAATTT CTTGTTACTT TTCTCACAAC TGCTAAAAAT ACTACAGTAA GCTTCCAACC AGGATGAGAA CCATTCACAA AGCTATATTT CAAATTTAAG TACTAGAATA CATTACAAAT TTTAAAACCC TAATGCTGCA CTGTCTACTA

TAGTAGCCAC TATCTGTGTG GCTACTCAAA TTTAAACTTG AATTCGTTGA AATCAAATAA CATTTAAAAT TCAGTTCCTC AGTGTCACCA GCCACATTTC AAGTACTCAA TAACCACATG TGGCTCATAG GTACACACTG GAAAACACAG CTATGGAACA TTTCCATTAT CACAAAAGCT CTACTGCACA ACGCTGTGCT AAGGAATCTT GGAGAGAAGC TCATCTAACT CTCTTAATGT ACAAATTTAG GAACTGAGAC CTCATTTCAT TCAAGTGACT TGCTCCATGC TACACGGCTA GTCATTACAG AGCCAGAGGC CAGAGCATGA ACCAAGATAC CCTGGACTCT GTAACTCACT CATTTCTACT GCAACGTCTT GTTACCACCT AGATGAGGTG AGTACATGTT CCTCGCAGGG ACACAGAATT AGAGTTTATT GAATGTGTCC TGTGTGCCAG GCACCATGTA ACCATGAGCC TATGAAGTTC ACACTATTAT TATCCTCATT TTACAATGAG AAAACTGACA TAGAGAGTTA AACTATCTTG

TCAAGGTGCC AAAATAAATA ACTGGTGAAT CTAGGACTCA AACCCAGCAG GGTCTGACTT CATAGTCTCA GCTCACGATC ACCATATGAC ACCATCTGCA CCAGGGAAGG GAAGGCATGC AGACCTGACT CTAATGCCAG CTAGGACGTG AGATGGTGCT ACCATCTCAA GTGAAGAAAG AGGCAAGAAC CAGACTTACT TTGCTCACAC TTGAGTCCAC TGAAGCCAGG GTCACACTTG CAAGTGTAAT TATTGATGGT CTCTACACAT TCACCGTGGC CACTGCAGGA TGTATTGGTA CAGGCAGCTA CGGAAAATAC AAAGCATGAT GAGGAGGACT ATTACTGTGC TTATACTGAG TGCCTTTGAT TTTAGAATCA ACAGTGTGCA ACAGAGACAT CAGCAGTCCT ACAGAGTGCC ATAGACTTTA ACTGAAGTGT TTTACAAAGT TCCAAATCTG AGTTTCAGGC CCACCTATCC TAAACCTTGA TGCTAATGTA TAGCTGTGGC TGGCACCTAC CGTAGAAAAT TTACTTCTTC ACAAACTCTG

AAGACAGTTC CCCTACCACA AATAAACAAG TAATTAAAAT ATGTATTGTG TGTGTGCATT TTTATATGTA AAGAACTACA TATTTGCCTA CAGTATTTAT ATATATTTTA TATATATACA TACACACATA TATGTGTGTA TATGTGTGTA TGTATATATA TAAAATGTAT ATAAATGCTG TAGGCTATAT ATATATACAC ACACACATAT ATGTGTGTGT GTATATATGT GTGTGTGTGT ATATATATAC ATATCCACAT ATTCTTGCCC ACATTCACAC AAAACAGCAA AAGAGAGAAA CTTTAGCAGT TAAACAGAAT CTTTTGGAAC ATAAAATGAC CACAATAGAG AGCAGTTTTT GCATGCTGTA AATTTGCCAA GATGCCCACA CACTGAAACT ACCTCCCACT GCTGCCGCAA ACTCCCTACC TGTGTAGCAT AGGGCAAGCT TCTTCTTGCT GCACCTCTCA TCATTCCACA TGCCCACATC TTTTTCTCTC TTGATGTAGA TCTCCACGCA GTCCTCATCT TTTTGCCTAT TGTTGGGTTC

ACCTGGAGCC CAGTTCTTGG CTTCTTCTGT CAGAGGTTTC TGGGTTCCTA CCCAGACCCA CACATTGTTG ACTTTTCTGA TTCCAATCCA GTAATAACTT GGTGAATAGC TCAATATGGA GTTTAGGTAC TCAATCTCTT CTTTGTTTTG AATTGCAACC AGGTGTGTGT ACCTTTGCTG ACAATAAGCA CTGGCCTCAT CATAAGTCAT AGCTTCCGTG GAGGTGTTGT AAGACCAGGC TCCACTCTCT TTAATGAGAA GCACTAGTGG GAGAAAAAGA AAAGAAATGG TAGAGTTTGG TACTGTTGTG GTTTAACTCT GACAACTGTG CTTTTTATTG TCTTATTTTT GGCAATGTTT GTGACATGGC CCAGACTTTT CTCATCTTTT CAAAAGTAAG AAGTACGTAT GAAGAAACAG CGACTTATTG TTTATCTCTT TTGTGACTGC CACCCACTAG GTACCTTATC CACACTCACT CACAACATTA TAGTATACCC ATTTTGTAGT AGAATAATAA TCAGAATAAC TAAGCTTTAT TGAGCACTTA

GTATGCACCA AGAAGCACTG TATGAGGTAC TTTCCATGAA CCATGCTATT GAATCCTCAC AATGCATCTG GGAAATAGGT CATTATGATC CACACTTTAC ACTTAAGGAA AGGGAGACAC CAAGAGGTAA AGTAAATGAC CCCAAGCCCA GGGAAGAACA CATTGCAGGT AGAGGTCAAG GATGCTGCCA GATATCCTGT GCAGGACAGC CCCAGACAAG CAAGGATATT TCAGTCTGAA ATATCTATAG TGCGAGAATG AGAAATCTTG GTCTAATGGC ACTGACTTAC CCAAAGTGAG AGCTGAGAGA AACTGTGAAG CAATCATGAC TTCAAGAGTT CTTTTCACCC AAAGGTTTAG GCTTGAAATA CTTTCCTGGG GAGATAAAAC ACAAAATGAA TTAAAGAAGG AAATCGTGGG TAGCTAGTTA CATTATTCTA CCATGATGTT TAAGGCAGCA TCCTAAGATT TTGGGCAAAG GACACTAGTG CAATAATCTT TATTTCAGAG TTTAATCAAA TAAATAAACA AATTTTAAGA

CTTTCATTAT TTAGGTCAAA GAGAAAAGAC AGGTTTTAGC TACAATACAA TAAGAGCTTG TACAGATGTG GTTTTTATTA GAAGGCCTTT TGCATATCTG TGTTTCATGG CCCGAGGCTG CCCTTATAAA GCGTTCTGCA CTTACCGTTT TGGGAAGCAG TTGTTCAAAC ACAGGATCTC TCAGGTGGGT ATCACTGCTG CCTCTGTCTC AGGTCAGTAT AGGAGTTTTG ATGTGAAGTC AGCCAAGAAC AGCTGAACAC TACTTCGGCT GAGGCCCTTT TATAGGAGGG ATTGCTTCCT GTGAATAATA GGAGGATATT GTCCACATCC AGTAAAGAGG AAATCCCCAA TGGCATCCAA AAACTTTCCC GGGAATATCC ACGATGCTTA AAATTACAAT GATGTCAGAA ACTCTGTCTC TTGAAGCTAC TTCACCTTTG TCCATGCCTT TATATCGTAT ATGCAATTTT ATTAATATGA CAAAAATGCA TGATTTTTAA TTATAATAAC ATAAAGTCTA TGTCTTTAAA AAGTTGTAAA ACTTTGCTTG

TTAGTAGTGT CTCTCATGTA GTTGTGGTAG TAATTAGAAT TTCAGAAACA GAAGGAAACC AAGAATAGGT TTGTCATCCA TAGTCTACTA CCTTCAATTT CTCATTCATA GCTGTGGATA ACCAATCACT ACTCATTTTT TCTTCCTTTT TCACCTGCCA ATTCAACATA TTTAACATGC ACTGTCTCAC AGAGGAATGA CTCACAAGGT AGATATTAAT CTTCAGATTT TGCACGGCAG TTATGCCTAA ATTAAAATAT TATCTAAAAA TAATATCTAA CACTCAAATG GTTAAAATAA TGCCTTATTT TAAAAAAAGA AAAATGGGAA ATAGATATTT ACATCTGGGA AAGTTTCATG GTTTGTTCAG TGAAAAAAAT AAAAAGGAGG CCAGGCACAG TGGCTCACGC CTGTAATCCC ACCACTTTGG GAGGCCGAGG CAGGCGGATC ACCTGAGGCC GGGAGTTCAA GACCAGCCTG ACCAACATGG AGAAACGCCA TCTCTACTAA AAATACAAAA TTAGCTGGGC ATGGTGGCGC ATGCCTGTAA

TCCCAGCTAC TCGGGAGGCT GAGGCAGGAG AATCGCTTGA ACCCGGGAAG TGGAGGTTGC AGTGAGCCAA GATCACGCCA GTGCACTCCA GCCTGGGAAA CGAGTGAAAC TCTGTCTTAA AAAAAAAAAA AAAAAAAGAA AAGAAAAGAA AAAAAATAAA ACGGAAAACT ATATATATAT ATTTAATTGG TCAAAATTTT GTTTAAAATT TTTGAAATGT TAATGTGCAA AGAATAAAAA TTCTTCCACA ATGTTAACAG TGACTAACTC TGGATGGCAG GATTTGGGAT AATTTTTATA TCCTTCATTA TTATTTTCAG GATTTTAAAG TTTTTTTCAA TTTCCCTTTT TTTCACCTTT ATAGTAACAA GAATACAGTT TAAAGAAACT TGTCTCTAGG CCAGGCATGA TGGCTCATGC CTGTAATCCC AGCACTTTGG GAGGCTGAGG TGGGTGGATC ACCTGAGGTC AGGAGTTCCA GACCAGCGTG GCCAATATGG TGAAACCCTG TCTCTACTAA AAATACAAAA ATTAGCCGGG

GTGTAGTGGC GCATGCCTGT AATCCCAGCT ACTGGGGAGC CTGATGCAAG AGAATCGCTT GAACCCAGGA GGCAGAGGTT GCAGTGAGCT GAAATCACAC CATTGCACTC CAGCCTGGGC GACAGAGCAA GACTCCATCT CAAAAAAAAA GAAAAAAAGA AAAAGAAAAG AAAAGAAATT TGTTTCCAAA TGCAACAGAA GGAGATGTAT GTGGTATCCT ATATTCCTGC TCTTCATTTT GACATTTCTT CTGGGTGATT GTATACATTC CCCATCTCTG CATCTTACCC TATCTAAATG ATGGTAACAG TAAATGGGGA TCATTTTAAT TTCCATATTC TGTAGGTTTT CAGAGCTCAA GTCAAGCTAA TATTCTATAT CTACAGCCTT TCAAAATAGG AGGTCTATCT AAAAATGTAC TGTCAGCAGA CCTGAACGAG TAGTGGTAAA AGCCTCGTTT TTCTCTTTAC TTGTTAGCAC TGGTCTTTCT GTGTTCATAA AGATGTCAAG ACCCAAAAAA AAAACAAGAA AAGAGAAGAA

AAATTCCAAA AAAGACAACT GATTAGAAAA AAATAACTTA ATTAACGAAT TTAATTCAAC CCCTATCAAA AAGCATAGAA TTTATTCCCT CCACCTTACC ACTCTCTTAC ATGATCCAGA TACTGACATT ATTCCAATTC TTTATCCCAC TTTACTTAGC TCAATGTGGT TGTTGCTTCA ATAAATTCAG AAGAGTAATC ACTCATATAG TGTTTATTTA GATTTTAGGG CAGAATGTCA AGTTGGGTTA ATACATTATC TGTATGTATT TTATTTTTAA TAAAGTATGA ATACATAATC TGCTATTTTT AAAAAGCATG GTCAAATGTA TAGAGTAGCC AAATCTTAAA AAACAATTTA TCTTCGATAT CAATAAAGTA CCTAATAATT ATATTGCTAA TAGAAATTAG TCGTTAACAT CCCTAGATAA CTAACTTTAT TATTGCGAAT TTTTCATAAC TAAGTTTATA GTTTATCTCT TCCCCTTTTT AAAATTAGTT CAAAGATATC TAAAAATAGC CCCAGTGGTG ATGAAGTTTC TATTTTACTT

ACATATATAT GTCCTGGACC CCCAATTATA ATCTCTAACA TTTATTGAGT GCTTACTATG TGCCAGGCCA TATTCTGAGC ATTTTGTATG TTCACCTATT GATTATTCAA TCCGTACAAC AGCCTATGAA ATAGGTACTC CTATTATCCC CATTTTACAG ATGAGGAAAT TGAGAATGTG GGGATTTTAT CTCATTCAAA AGCACAGAGC TAAGGGTTGA AACCAGGCAG TTGATATCCA GAGCCCACTC CCTTACCTGC TACTCCAAAC CATGATTTCT TTTGTTGTTA TGCCCCGAGA TTCCTTGTTC TACCCAAGTT TCCTGTACTC TTCTTGCCCT CTTCTTCCTG AGACATCCTT GACCATCACA GCTCTCCACT GAGATAACTG TGTCCTGGGT TCTGAGACAT GGGGGCTGGA AGGGACCCCA GGGACAGTGA GCAGTAGGGA GAGGATGCAG TGAGAACAGA CCCTGGATCC CCGGTGCATA GGCAGGGAGA AAGTGGACAA AGGAAAAAAC AAGCAAGGCA GGTGGAGCCA

TGCCTAGGTA AAGTTGATCC CTAAGCCACA GTTCCCAGAA GTTCCTGATT CAAAAGCAAA TTTTCTCTAA GGTCAAAGGG CAAACTGATT ATTCTAAATT CTAAACTGAT TATTTCTAAA TTGAGAAAGC TTCAGGGAGA GATCCCAATA TTCGAAGGAT AAGAGAAATG AGGAGTGGAA GAGATAGGTG AGTAACAGTA ACTTAAATGT AGACTATATA TAATATATAA TATATGTAGA GTATATATAT ATAATTACAA TATATTATAT ATGTGGAATA TATATATTAT TTATATATAT TTATATATTT TATATATATA GATATTTTTA TATTTTATAT ATAAATATAG ATATTTTTAT ATTTTATATA TAAATATAGA TATTTTTATA TATATTATAT ATAAATATAT GTAAAATACT GTGAAAGAAG AATAGAATCT TGAGACCTCA AATTCACTAT GCCAAAGGGA AAGTTAAGCT TGGGAAATGA GTCATGCAAA AACTGCCTTC CTTTTGTTCC CAAATACCTG TAATTTCACA TGCTTACTTT

ATCTTATATA AAATGTAGAT GTACTGAGCA TGAGATCCAT GCATAATTTC CCTCTAGTCC CTTCTTTTTA CATGTAAAGT GTAGACTCAC TGAGTGTTAC AGAGCCTTGC CACAATGTAA ACACTTGTCT CATTGCCAAC CCATCTTTCG TTTATTTTCT TCCCCTCCTG CTTGCTCTTT CCCCTCTAAA GATGGAAGTT CCCAAAACTC TCTTTGGAAA AAGCGCAGGT CACAGATCCT ACAGTGATTT GTGTTTCTTT TACCTGGGAC AAAATAAACC TCTAATCTGT TGAGATATGC TTCAGTTACT TTTTGGTTTA CAATATGTAC ATGTATGTAT ATAATTTATA TGTATATAAT ATATGTACTT GTTTTAACCA GAGGTATGTT ATTCAAAATC CATTCATCCT TACAATTACC TGCATTCTCC CACAGTATTT TCTGTGTCCC TGCCCCCGAG GTTGTCACTG CAAATCAGGT ACATGGATAC TGGGAGCTGA TGGGCTCCCC TCTGGCTACC TGGGCTGCTG AAGGGGCCAT AGACAGACCC AGCTTTCCTC TCGTGGAGAG GCCCTGGGCC AGCGCTGCGT GGGAGTGGGA TTACAACCAG ACTATAGCTT CTTCACCTGC TTTTTCCTAT CAGGATTTCA TAAGAGGCAA TTGCTTGTTT TTTGAGGGTG GGGGCAAATC AGGGGGAGTT GAAGAGGAAA TTGGGTAAGA TTTGAATAGT TGGGCATGTT GAATATTATG AATATCATCT CCCTCTTCAA ATAATCCAAA ATATACCCCC AAGAAACAGG CTGATTAGAG GTGCTTCAAG GCTCCACTGA ATCTCCCAAG CTCTGAAGAT GTAGCTAGCT GTTACCGGAT TGCCGGTTTT CAAGCCTCGC CTCACATGGA CCCTCTTGGC AGTTTCTCGC ATGGGGGAAG CATCCGCTAC ATAGATGGGA ATGAAAAGAG GAAAGAAGAC GGTGCAAACT CAGGCACACC

CCGGTGTCTG CCACCAGTGC TATTTAATCT CTGAGGTGTC ACCCTTCCTG GCTTTATTGT CTCTTCCTGG AAGTCTCTTG TCCTCTCCTC CACACCCTTT AATCAGGCAT CAAAGACTTT AACCAGTTTT GCTGTGTGCC CAGGCCCACT CATTCTCACT TTTATGGCAA AGGGAGTGGG AGACAGAGAG ATAGCCAGAA AGAAGAGATT GGGGACCCCA AGACAAATGT TAGAATTTTA ACCAAGGCCA CCCTGTGGAC AGGAGATTAT TGGGTTTAGT GGAAAGCAGC ACTGGCCACA ACCACACGTG GCAAAAGCAT CTATCGAGGA GTGAAGTTAT ATTTGGTGAA TGTGACCGGG AAGCAGGGGC AGTGGTGTCC TCCTGCCTTC CTGAGGCACT CTGTTCCCTT ACCTCTGCGA AGGCTTATTT TACCCCTGAG TGCTTAGTTT TGAAAGCCTT AGTTCCCTCT CTCCCATAAA AAAGCTCTAC TCTGCTAACA TCTAAGTTAC CTTTGCAGAG TCTTAGGTAG AGGGAGGAAA TCCCAATAAA

GATTCCACCC TATCTGCAAA ATACAAACAT GGTATTTCTT GCATTCCCAA AATTGTGAAA GAAAATGTGT ATCACCACAG TAGAGAATGG CATTTTTTGT TTGATCAAAA CCTAAATATA TTTGATGAAA ATGTGTCTGG TTCTAAGTTT ATTTCCCAGA AAGCCATGTT TACTCACTTG GAATTTATAG ACATCTTATA ATATCTGAGT CGAGTAGGAG CTCCGGGCTC TACCTCACTC TTTTCTCCCA CACCCAGGGG GAAGTGTAGG GTTCTCAGAC TTTAGAATAA AGAGGAATCA CCTGGACAAC TCACCTAAAA TGCACATCTT CAGGTCTCAT ACTCAGAGGC TCTGACTCAA CAGGTCTGGG TGGCGCCCAA GAATTTGGGC TTTAAATGAG TATCTCAGAT GATTCTAATA CAGAATGTGT AAGATGACCA GATCCTATCA CACTTAGATG TATTGGCCTA GGGCCACCTA ACTTGGAGAA AATGTTAGTA AGACCCCGTG GTTGGTGCTC AGCTATAGGT ACCAGAATTT TGATCAAAAT

TTACTATCAT TGTGACACTT CTCTTCGGAA CTGGAAGGCC AGAACCCCAC TTGTAAAGTG CTGGGAAAAT ACAAGGAAAA TTTAGGGTGA GTAGCATTTT GAATTCTTAC ACATGGAAAG TAAATGTATA AGAATTCTTA CCAATAAAAA AAAAGCAAGA GAGAATAGCT GCTAAAGAAT TAACACAAAT ATGTATATAT TAGTTATTCT CTTTTCTCCT CTGATTCCAG AGGACTTTGT AATTCCACTA ATTCTTCTTG AGCTTCCAGG ATGATCTGAG ACTTGAATTT TTCATGTGCT TTTTGCTTCC TATTTGGCAG CATCTTATCT TGAAGTTTCC GCTTTCTGCT TGGGGACCTA AAAACTAACT AATGGGAATT TCTTCAAAAT GAGCAAACTC TGGTGAATTC CCAAAGCGGA AGAAACAAGT GAGGATCGGG CTGGTTAATT AAGAGAACTT TTCCTGAATG TAGCCAGACT GTTTGCCGAC TGTTGTTAAC ATGAGGGAAG AAATACCCCT GGATTTTAGA AGAGCCCCTT GTTTGTTTTC

CTTGGCCATT TGTGCTGCTT GTTTTGTAAG TCAGAAATTT CCTGAAGGAC TATTATTAGC TTTGTTCTCA CGTCAGAAAA CTTCTGCTCT GGCCACTTTT AAACATATAA CTTGGATTTT ACTGTATTAG AAAATGTAAC AATTACAGAC AGCACTAAAA GGACACCAAA GGGCAAAGAA AATGGGTAAC TTTTTTTTCT TCCCCAAATC TAAAATAGGT GATTTTGGAG AAGTAGGAGA AAAACCTGGA TTTTCTAGAT CTCTTTAGAG CTCAACAACT GATATAGTTA ATTATGTAAG TCTTTGATAT TTGGAAATGA TTGGATTAAC CGGATAACAA TGAATATTTA AATACAGTGA TTTGGCCAGG AGCAGTGGCT CATGCCTGTA ATCCCAGCAT TTGGGGAGGC TGAGGCGGGT GGATCACCTA AGGCCGGGAG TTCCAGACCA GCCTGGCCAA CATGGTGAAA CCCCATCTCT ACTAAAAATA CAAAATTAGC CAGGCGTGGT GGTGCAAGAC TGTAATCCCA GCAACTCGGG AGGCTGAGGC

AGGAGAATTG CTTGAACCCG GGAGGCAGAG GTTGCAGTGA GCCAAGATCA CGCCATTGCA CTCCAGCCTG GGCAACAAGA GCGAAATTCC ATCTCAATAA ATAAATAAAT AAATACAGTG ATTTAACACA AGAGATTTCT ATTTCACACT AATGAGCTCT GTCACTGGGG CAAGCTTCTT TGCCTCATTA AGTCTCAGAT TTCCCGAGAG CTTATTTATT TATACCAAGA GTGCTTTACT ACCGTCTCTG CTAGCTGTGA CATAATATGA CAAAAGGTAT AAATATGGGA AAAGGCACTA ATTTATATCA AAGCGTTCTT CGTTTTTCCT TGCTGTGAAG TTTTTAGCTA ATAATTCATA AGAATATACC ATATTTAGAG TGTTTACTAT GCATGGGCCT GGCACTTCAC ATACATTGCT TCTTACAAAT TTTACAAAGT GAAAGGTAGA TATTAATCTC ATTTTATGGA GGACAAGATA GAGATCTGGA GAGGTTACAT AACTTGCCAG TGTTTTTTCA GTTAATAAAT GGTAGGGTGG AGATTCAATC

TGTGTTACTC TAAAGTCCGT GTCCTTTTTA TTGGCTCCAT GCCTACTCAG ATTTAAATCT CAGCAGGGAA GTAAACCTTA GTTTTTACAT GAGAAAATGT TACAGCAGCC TTCTCGGcrr TCACGAGCTT AGTGCCTTAG ATCGGGTTCC TTTAGAAGCA GACCTCGAAA TAAGGATGTG GGTGCCAGTC ATTTATTGAA AAGATGATCC CAAGAAAGCC TAGTAGGAGA GTGAGGAAGT GAGATGGGGA AAGGAAGAAA CTCCACAAGA AGTGTGTTAA TAAGCAGGTT ACCGCTGTGG GCAGCCATGG GGCTCAGCTG CACTAACAAA CTCTGTCTAG TACAGAAAAC CTCAGGGTCT CCCCAAGGAG GGGCAAGAAG TCTGCCTAGG GTATATATCC GCCAACTCAG TCACTGGCTG AGAGCTGATC CTGGGAGGGC ATGGTTAATT CCTCTGCACT TTCAAGTGGA TTCCTGTGGT CAGAAAAAGC CCTCTACAAT GAATTCCAGA TGCTTGTATT

TAAATCTGAC ATGATCTGAA TGCTGTGTTG GGACAGGGTG GGCGTTATTA GTTTTCTGTC ATTACTGTAA CAGATTACTA CAAACCTGAT GGCTGCAAAC AACACATATT TATTATGTCA TAGTTTGTGT GGGTCAGAAG TACAGGTTAG CTCAACTAGT TTCTCTGCTC TAGGTTTCAC ATTGCCAATA TCAAGGTGTC ATCCAGTTGG GCTCTTCTTG GGAGGCTTGG GGATGAATCC ACTTTCAAGC TCATTCAGAT TGTTGGCAGA ATCCAGTTCC TTGTGGTTGC AGGACCAAGG TCCCTGTTGC CTTGCTGGCT GTTGGCCAGG AGTCATTCTT AGCTTCTAGA GACTACCTGT ACTCTCTGAC TCGTGTCTCC ACTTCACCTT TCAAACCAGC AGCGGCTAGT CGAGTCCCTC TCTTCAAATG TCTCCAACTG TGCCTTCACC TCATTTCTCC TCTGTGTACC ATGTCTGCCT CTACTGCTTG TAAGGGCTCA TGGGATTACA TTGGATTTAT TCAATCCAGG ATAATCTCCA TATTTTAAGG

CTAGCTGACT AGTGATCTTA ATTCCATCTA CAAAGTCCCT TCCAATAGTA CTGTATTAGT CCATTTTCAT GCTACTGATA AAGACATACC CAAGACTGGG CAATTCACAA AAGAAAGAGG TTTAATTAGA TTTACAGTTC CACATGGCTG GGGAAGCCTC ACAATCATGG CAGAAGTCAA GGAAGAGCAA GTCATGTCTT ACATAGATGG CAGCAGGCAA AGAGAGAGAG CTTGTGCAGG GAACTCCTCT TTTTAAAACC ATCAGATCTC ATAATACTTA TTCACTATCA CAAGAACAGC ATGGGAAAGT CTTGCCCCCA TGATTCAATT ACTCCCACCA GGTCCCTCCC ACAACATGCA GGAATTCAAG ATGAGATTTG TGTGGGGACA CAGCCAAACC ATATCAAGTA CCTAGATTCA TGTTTGATTA AACAACCAGG GAGCAGAAAT CTTCAGGAGT GGGGGGCATC TTTAGAATTC TGCCCACCAA GGCTGGGCGC GGTGGCTCAC ACCTGTAATC CCAGCACTTT GGGAGGCCAA GGTGGGTGGA

TCATGAGGTC AAGAGATCGA GACCACCCTG GCCATGGTGA AACCCCATTT CTACTAAAAA TACAAAAATT AGCCAGGTAT GGTGGTGGGC ACCTGTAGTC CCAGCTACTC AGGAGGCTGA GGTAGGAGAA TCACTTGAAC CCAGGAAGCG GAGGTTGCAG TGAGCCAAGA TTGCGCCGCT GCACTCCAGC CTGGGAGACA GAGCAAGACT GTCTCAAAAA AAAAGAATTC TGCCCATCAT AGTAGGCTGT CCTACAGAGA CATAACCCAG GAATTAGGTG AATGGCTAAC CTAAATTAGC ACTGTGATGT GTTTTCTGAC TTGGTCCTTA TAGCTCCTCT GCTTAGATGT GGAACTAATC CATGAATGCA AGGGTTTGTC TAGAGTTTTA AGTGGGAGTT AAATATCCAA AGTACAGGAG ATATTATGGG TGCCTCATCC ATGTCCCCTT GGCATTTATC TTTCTTGGAT AACCCAACTC TATTAGTTTT TATATCTCAC TTGTTCCTAT ACTCTGTGAA CTGATGTCCC ATAAATAGAC

ATTTCATTTT GCCAGTCTTC TTGAACAATA ATTACGATTA TTAATCTAGC AGTTATCATT AATTGGCCAC TTCACATTAG ACACAGCACT TAGGACTTAA GAATACCATG TCATTTGATC ATCATAATAT GGTCAGGAAT TAAGTATTGC TATCCAAATT TTACAAAGAA GGCACTGAGG GTTAGAGTTT AAATAACTTG CTTAAGATGT CATAGCCTGT AAGTGACAAA ACTAGGACTC AAATACAGGT CCATCTGACT CCAAAGTCTA TGTTCTTGGC TACCACACTG CCTCTCCTAC AAGTGACCTG TGGTTTTACT ACTATATTCA CACTCTACTA ACTTTACCAT CTCCCATGAG TCTGTCTAGA GGAGGGCACA CACAGCACAG AAAACACATG AATGCAAAAT AAGGAAGGGC CTACTTACTA CACAGAGCCA TTCTAATACC TGATGTTTGC TCTAATCCAG TTTTACTATT AATTAGTTGC TGGTGCCCAA GTTTTTACTG AGAAATGGGG ATAATTTTGG AAGTCATAAT GATGCCTTCT

TCTCATAGGG TATTTTATTT GTTGTTGTAT CTCCAGGCCC CAACACAGCC TGGCTTTTAG TAAATGATCA AAAATACCTG TTGAATGAAT AAATGGAGTC ACCTGAAACA TGTTAAACAT TTGTTCATGT GTCCTAATCG TGGATTTCAG GATAGTAAGC ATCCTAAAAG GAAAGCATGC ACACTGTTCT TGCTACATTA ATTTCTCACA ATATAAAAAA AGAAAAGCAT CTGAAAAAAG CTGCCAGCCG CTGTGTCTCC TAATATCAAA CTGAGCACAG ATATGGAGAA GCTAAGGGAG AGGGATGATG GGCCATGCCT CTAACCTCAT CATGGCAAAA GTCCTGGGGG TCAGACCCGA GGAGAGCAGG AAGTGTCTTT TGAGGGATAC ATTTCCACAG TGGAAATAAT GAGACTTAAA TAAATATTAT ATACACAGTT CAACTGTTTT TATGTGTAAA GGTAGTAGGT TTTCACAGTA AGGAAGCACT TCTTTTTTTT TTTGTTTGAG ACAGAGTCTC GCTCTGTCTC CCAGCCTGGA GTACAGTGGT

GCTATCTCGG CTCACTGCAA TCTCTGCCTC CTGGATTCAA GTGATTCTCC TGCCTCAGCC TCCCGAGTAG CTGGGACAAC AGGTGTGTGC CATTACACCT GGCTAATTTT TGTATTTTTA GCAGAGATGC GGTTTCACCA TGTTGGCCAG GCTGATCTCG AACTCCTGAC CTCAGGTGTT CTGCCCGCCT CTGCCTCCCA ATGTGCTGGG ATTACAGGCA TGAGCCACTG CACTCACCAA GCACTTCTAC TGATAGCATT TACAAACCCT TCTTAGAATA TTTAAAAATT CTAAGAGAAG AGTAAATTGA GCCTTCCCAA CTAATACTAG GAGGTTATAA CCTTCATACC AAAACTGGAC AATGCTTGCA CAAAAGAAGG AAGCCAATGA GGCCACCTAG AAGGAAGACT GGGCATTGGG CCCAGTGAGT CCTGGAAACC TCATCTGTGC CAGCCACCCC GGCATGGCCT GTATGAGTGG ATGAGGGTGA CTTGTCCACA GACAATAGCC ATCTAGCTGT GATAAAGGAG TCAAGGTAGT

CAGCTGCATC TCTTTCACCT GTTTGCCAAT GTTACACAGG TTGAAAAGCT AAGGTTTATG TAAAGCAAGC ATCAAAGATG ATGAAATGAT CAACCTGACA ATGAGTACTA TGCTGCATTG TCCAGAAAGG AACTGTGGAA GATTTTGGGG TGAATTTCAA AACAGAATTT CCTCACTCTC TGGATGTTGG CTTACTTGGC CTTTGATGTT CAGAGGTGGT GCCTTTGTGT TGTTGAACAA TGTTGATTTT GGAGAGAAAA CAGAGTTGAA AAACCCACAA GTCATTCCCT GGGGAGTATT ACCGGAATAC AGAGGATAAT TTCAGCAAGC CAGCAAGGCC TCATCTCTGC TTCTAATAGA TAGGAAGAAA GGAAGAGAGG AACAATACTT TTTTAAGAAG CTCAGCTTTA TCGCCTTATC TCATAGAAAG ATGCCTCCAG TCTGTCTGGC TAAAGGTAAT TGGCATGGGA AAGTCTTTAT CTGTGATTCT AACAAGTGGA ATGTTTCCCT TCATTAAGAG AGCCTTGTCT GGCTTGGGGA AATGAAACAC

TTTCTCCGAT ATGAGTGGGC TGTAACCCCT GCTACTAAAT ACTCAGAAGA AATAAGGCGG TTGTGGAGCA GTCAGGAATG AGTCACTTGC CTCCCTGGAA TATTCAGAAA ACTGAATCAA AAGTACATTC TTCTGGGTTT TCTTAGTCTA ATAGACTAAG GGTCTCTACT TTGTTAAATT TCTGGGAAAC AGCATAGAAT GGGAGAAAAA ACTGGTCACT GTAGTCATGC AAATCTGCAA AACAAACAAA AAAGTCTGGG TATTGCTGCT AACTAGCTAT GTGACCTTAA GCAAGGTATT AACTCTCTCT GAATTTCAGG TTCTTCATCT GTTAAATAGC ATATCTGTAA AATGGGAATT ATTTTCATAT CATAATGCTG TAGCTTTAAA AAATAAAATA AAATGGATGA GATAATCAGA ATTAAAGAGC CTGGGATATA TAGTTAATAT ATAGCAGCAT GTAAAGATCC TGTTAGAAAT GCTAATTTTA CAGTTAACCA TTTGGAGATG ATCCGCCAAA GCTGCTAGTG TAGAGGCAAC TGAGAATTTG

CCTGTCCTTC AGAATATGAA TAAATAACTG TCAATGATGT CTCAAGCCTA GAAAAACCTA TCCATCTGGA TGGGTGGGAA ATTTCTAGGC TAGTATTGAG AAGCCCATTT CTTGGGAAAT AGGTCCTGGA CTGAGTGAAG GAAAAGAAAC AGTAAAACCC ATGGTAAAGC AGCAAGGCTC TCTAGAGGCT CTGGAGAGGA TGAATTGAAT TCTAGAAGAT GAAGTAGGGA AGACGCTTTA CCTTCTTGTG AAATGGATTC AAAGATTCAA AGACCTTCGG GAATCTCCAA TTGTATAAAT GGCACCATAG CTGTATGTTC CATGGAACAC TACTTCCCAG AGATGCCCAG TGAAAAAAGA ATGCCACAGT CAAATAAGTT TGGAAACACT CCATTATGTG GCCACCTCCT TGAAGACTCT AATGCACATT AGCATGTTAA ACAGTCTTGA GAAGTCCTGC AGAGCAGAAA TTGCTTCACA TCTGCTAAGC CGGCAGTTTC CCAATATACT TGATTATGGA TAGTTTTTTC CTTACAACAC

CATTCTCTGA TATGCTTCCA ATGACATGAA ATAAATATAT ATGCATGAGG TTCTTCATTA GGGCATACTT TTTAATAGAA AATATTGAGA ATAATCTAAA TATAAATGCA CAGCATTTAC CTTTTCTGCA TAAACTATAT ACAGGCATAC CTTGGAGATA CTATGGGTTT GGTTCCCACA ATATCTCCAA AACCACATTC GGTTTTATGA CCACTGCCAT AAAACCAGCC ACATGAATTT TTTGGTTTCC CAATGTATAT CAAAGTTACA TTTTTACTAT ACCATAGTCT ATTATATATA CAATAGCATT ATATCTAAAA AACAACGTAA ACACCTTAAT TTAAGGCTGT GGCTGGTTTG ATTTTCTACC CAGACCACTA AAACTTTCTT CATATCAGCA ATAAGGCTGT TTCACTTTCT TACTATTTTT TGTGATAGCA CTTTTCCTTT TTTGTTTGAT ACAAGAGGAC TTACATTGTT

GCTAATGATC ATCTGAGACT TCAGCAAGTC ATAATCTTTT GCTGGTGGAA GGTCTTGCCT CAGTGTTGAT GTCTGCTGAC TGGGTGGCTT TGGCAATTTC TTAAAGTAAG ACAACAATCA AGTTTGACAT ATCAATTGAC CCTTCCTGTC ATAAATGATT TTTTTTTTCT CTGTAGCCTG CAATGCTCTT TGATAGCATT TTACCCACAG TAGAATTTTC AAAATTGGAG TCAATCCTTT CAAACTCTGG TGCTGTTTTA TCAACTAAGT TTATGGAGTA TTAGAAATCC CTTGTTGTCA TTTCAACAAT GTTCACACCA TCTTCCCCAG GAGTATATTC TACCTCAAGA AACCACTTTC TTTGCTCATC TATAAGAAGC AGCTCCTCAT CCACTAAAGT TTTATCCTGA GATTGCAACA ATTCAGTTAC ATCTTCAGGC TCTACTTCTA ATTCTAGTTC TCTTGCTGTT TCTATCTCAT TTGTGCTTAC TTTCTCCGCT GAAGTCTTGA ACCCCTTAAA GTCACTCATG AGGGTTGGAA TCAACTTCTT

ACAAACTCCT GTTGATGTTG ATATTTTGAC CTGCTCCCAT GATTCATGGG TATTCTTAAT GGCATCTAGA ATGGTGAACG TTTTCAGAAG GTTTTCAGTT GGCTTTGCCC GGATCCATCA GACGAATCCC TATCTATGGA AGCTATAGAT TTATAAAATG TATTTCTTTT TTTGTGGGGG CATAGCGTCT CACCCTGTCA CCCAACCTGG AATGCAGTGG CACAGTCATA ACTCACTGAA GACTCAAACT CCTGGGCTCA AGTGATTCTT CCACCTTGGC CTCCCAAAAC ACTGGATTAC AAGCTTGAGC CACTGTGTCT AGCCCAAAAT GTATATCATA ACTAATGAGG CTTGAAAGTC AAAGTGACTC CTTGATCCAT GGGCTACAGA ATGGACGCTG GGTTACCAGA CATGAAAACA ATACTCATCT CCTCATACAT CTCCTTCAGA GCTCCTGGGT GAGCAGGCCC ATTGTCAAAT GAGCAGTAGT ATCTTGAAAG AAATTTTTTT TCTGAGCAGT AGATCTCCAC AGTGGACTTA AAATAGTCAG

TAAACTATGC TGTAAACAGA AGTGCTGTCA TCCAAGCTCT GTTTTTCCAC TGATAGGGCA AAAGCAGAGT AGATTTGGCA TAATTCTCTA GGGCCTTAGG ATTTTTGGAA TGGCAAATTG AGCATTGGCT TCAACTTTTT χχ_Tχχχχχχχ XXTxxxxGAG ACAGAGTCTT GGTCTGTCAC CCAGGCTGGA GTGCAGTGGT GCAATCTCGG CCCACTGCAA GCTCTGCCTC CTAGGTTCAC ACCATTCTCC TGCCTCTGCC TCCTGAGTAG CTGGGACTAC AGGCACCCGC CACCATGCCC GGCTAATTTT TTGTATTTTA GTACAGACGG GGTTTCGCCA TGTTAGCCAG GATGGTCTCG ATCTCCTGAC CTCGTGATCC ACCCGCCTCG GCCTCCCAAA GTGCTGGGAT TACAGGCGTG AGCCACAGCG CCCAGCCTGT CTTCAACTTA AAGTCGCCAG CTGTGTTAGC CTCTAATAAG AGAGTCTGCC TGTCCTTTCA AGCTTTGAAG CCAGGCATCA TTCTCTTCTC TAGCTATGAA AATCTTAGAT AGCATCTTCT CCCAATAGGA AGCCATTTTT TATGCCCTAA AAATCTGTCG TTTGGTGTAG CCACCTTCAT CATTGATCTT ACCTAGATCC GCTGGATAAC TTACCACAGT GTCTACATCA TTACTTCTGC TTCACCTTGC ACTTTTATGT TATGGGGATG GCTCCTTTCC TCTAACCTCA TAAACTAACC TCCACTAGCC TCACATTCTT CTTTTACAGC TTCCTCGCCT CTCTCAGAGT TCACAGAATT GAAGAATGTT GGGCCTTGGA TTACACTTTG GTTTAAGGGA ATGCTGTGGC TGGTTTGATT TTCTATCCAG AACACTAAAA CTTTCTTCAT ATCAGCAATA AGACTGTTTC ACTTTCTTAC TATTTTTTGT GATAGCACTT TTCCTTTCCT TCAAGAATTT TTCCTTTCTA TTCACAATTT GACCGTTTGA

TATGAGAGGC CTAGATTTTA GCCAATCTCA GTTTACACCA TGCCTTTTTC ACTAAGCTTC ATCATTTTAG CTTTTTATTT AAAGTAAGAT GTGTGACGCT TCCTTTCATT TGAACACTTA CATGATGATG CCTGGCTTCA AAGCTTGAAA GGACAGGCAG ACTCTCTTAT TAGGGGCTAA CACAGCTGGC GACTTTTAAG TTGAAGCCAA TGCTCAATTT GCCATTAGAA GCCATTGTAG GGTTAATTAA TTTGCCTAAT TTTAATATTA TGGTGTCTCA GGGAATAAGG AGGCCTGAGT AGAGGGAGGG AGATGGGGAA ACAGCCAGTC ATCAGAGCAC ACACAACATT TATCAATTAA GTTTATCACC TTGAGGGCAC AGGTCATGAT ACTTCAAAAC AATTACAATA ATAAAATAAA AAATCATTGA TCGCAGATCA CCATAACAGA TATAATGATA ATGAAAAATT TGAAGTATTG TGAGAATTAC CAAAACGTGA CACACAGACA CAAAGTGAGC ACATGTCATT GGAAAAGTGG TGCTGATAGA

CTTACTTCAT GCAGGGTTGC CACAAATACT CAATCTGTAA AAAATTCAAT TATCTACATA GTACCATAAA AACAAGGTAT ACCTGTTTAT ATAATCAAGA CCAACAGAAC CCTAGAGAAA ATAGCTCACT CCCTAGCTCG GAGACATTCT AACCAACATA CACTTACCTT TCTTTTTGCT GTGTACAGAA TTCAAATCCC TGTCTCAGCA AAATTGCAAA GTATCAAATG TCATGTCCAT CTAATACTCA AAACTGCAAA TGTTAAGTCT TGTAAGCCCA GAGACCACTG TATATACAAG TGTTGCTATA AGCATTAGTT CTTCTCCAAA GAAAATAGTC CACTTGGTAG AAACAAACAA AAAGAAAAAA AAAGAAAGAA AAAACATTTT TTACAAGAAG ATTCAGTCTC TTACCTACAT AAGCAAAAAT ATGAGATGTT CTCTTATCAT TTTTCCATCT ATCTTATAAT CTTTGGTGCT GACTTAGACA CTCATTTTCC TTTTTGTACG TGACCATGTA AAAGTTCAAG TCAAGAAAAA CTTGTTTTGA

CATTTGTTTT GCTGAGTGAT GGGTCCCTAA AAGAAATTTG GCTTTGCTTT TGAAAAGTTC AGCATGATAT TGTGTGAATT TTTCATGGCT AATGATTTTT AGAACAGTTG TGATGTGTTT AGGTGTTTTA AGAATATGAA GCATTCAGTG GTTTAAGTTG GTTGTTATAA AATGAAAGAA TATGAAGGAA AGCCTTCTTG TCTTAGAACA CACTGATTCA CAAATAAGCA GCTTCTCTCA AAATGTTGTA ATTACAAAAA TTCCAAGGCA AATATAATAA ACTCCTTGTC GGTGCTATGT CTAGAAACTT AACAGCCCCA AAGAAAGTCC TGACAAGGCA AAAAATATAT ATATATATAC AAATTGTGGA AGCAGGGTGT TGAAAGAAGA ATAAAGACTA TATAAGGACA AACTGTTTAA AAGGGAGGGT ATCCTTGAAA GCTTGACACT TGACTCTTTT GACGAGGCTG AGGGAAAACA CTCAGTTTCA TAGATTGCTG GTACGGATGT AAAATAGTGA CATCCCTATA GAGAGGAATT

TGGCAATATC TAGCAAAAGT GCTTATGCAT TTATTCTTTG ACCTAGTAAT CCCGCTTCTA GGATTAGTGG TGAAGATACA CCTCAACAAT AAAAATATAT ATACATTAGG TTATTAGTTA TGGTTTAATT TTTAATAGCA AAATATTTAA AACAACCTAC ATGAACAAAT AGGAGACTTA CTGAATAAAC TATGGTATAT CTGTACAATA AAGTGCAATT CACTTATGTT GTTAATTTGT TCCAAAAATC CAGAGCCAAA GAGTATTTGT TATGCTCTCT TTAGTATAAG AAAGGGGAAA TAAGATATGT GTGCATCTGT TTATTTTTGT GAAAATAAGT ACAGAAAGGA TAAGTAAGAA ACTAGTAAAA CTAGTTATCT CCTAGTGTTA GTAGAAATAG AATGAAAGTG AATTAGGCTT CTTTGAGTAT ATGTTTATAT ATAGTTTTGA CTTTTGAATT ATGTTTATGT TTACATAGTC AAAAATATAA ATTAATCAAC AGAAATAACA AAAAAAGAAG AAATGACAAG CTTTAAAATT TAATACAAAC

AGAAATAATT GAATCTAACA GTATATCAAA GTGATAACGT AAACTCAGAA GAAAAAAACA TAATCCAACA TACCAGTGGA ACACAATATT CTAACTGTAT ACATTCAGTG GTTATAGTCT AAGGACAAGA AAAATTGCAA AAATATCTTG AACTTTAGCT TGTAGGATTT TTATTGGTAG CAATACTAAT GTACTAATTC TGAAATTAAT GTTCGTGTAT TATAGAATTG AGTAAATGAA TAAATATGTT GATGTTATTG GGAACTAAAA TTATCATTCT GGGAGTAGAG AAATATAAAT ATGGACTTGG CAAATGAAAC AAAGACCTGC AGAGAGATAA CCATATAAAC TCATTATTTT AAAAATTATA AGTGTCCTAG CTCTGTTACT GAAAAGGCCT AGATTCAATC TTATCTTGAT AGACAGGAGG GCACCCCTTT CTCAGAACAT GGTTTCCAAA TGCCATTCTC CATTAAAAGG AACAAGGTCT TCTTGGAGAA AAGACTGATT CTAGGTCTGG ATTAGGTAAA GTACAACGTT AGTCTGGAAT

TTCTTGCTGA ATCAGAAGTA AGAAAGTGCT CAAAAACATG GGAACATGTC ACAAACACAC GTGAGGCAAC TTGAATCCTC ACTGGCCATA TTTAGGACAA TCGAGCATCA AAAAAAAAAA AAATGTTGAG AATAATGGAT TCTAACACTT AAAACAAAAA ATAATCCATA GCCCACAGAA GGGGAAGAGA GGGGGAGCTC TTATTTACAG ATGAATATCA AATAGCAAAG ACAGAAGAAA TGACAGAATT AGAGAAACAT CATTTTGCAA AACACCACTG TAATAATCAA TTCAGGCAAG TATTATTAAT GGATGTATTA CTATTGCGTA AAACCAGTTG GGGAACAGGA TATTCATACA GTCTGAAGGT GTCACCCTAA ACATAACTTA TTACAAGTGG AAAATGGTGC CTTTACAATG AAGAAATCTA GCAGAAACCA TCTTAATCTA GTGATCAAAC TTAGTATCAC CAATAATGGA TCATACTGAG TCATGTGTCT CCTAATATGA TGCACCAGGA AGGATGCAAC GTCATGAACG

TTGTATTCTT TTGTATTCAA CAGACCACCC AGGGTAAAGG CAGCTTTCTC ACTTACTAAT CAGAATTGTT GGTTTTAATT CATTTTGGAT TTTAAGATTT CTTACTTTCT TGTCAGCTCA GAAATTTATT TAAGATGATT TTTATCTTTT ATTCAATACT TTAGCTTGGA GAACCATTCA GAGTTTCTAA CTCATTGTAT TGCCAAAAAT AGAAAACAGC ATGGTTTCTT TTGAAAATGT CTAACTTTAA AGTTACTTGT GTGTGTCACT CAGATTCACA TAGCTTTTTT GCCTAGTAAT GTAGTATCAT GTGGCAAGGC TATAAAAATG TTTACAATCT TTTATTTAAT ATGACTCTTG AGAGTTTATT CTAAGGAAAT AATTGAATAG TAACAAAACA CTATTAACAC AAAGCATAGC AATTTGATTT GGGCAACCAA ACACTGGAAA CAACCTAAAT GTCCATTACA GGAATCATTT ATGAAGCAAA CACTAAAATA TTTATTGTGA AGATTATGAG AACATAGAAG ACAGTTATGA GAGTAAATTT

GAAAACCTGA ACACAAAACT TACATATACT CCAATTGTAA CTTATAAAAA ATACGTGCAT ATAAGGATAA AACAGTACAA ACAAAAAAAT AGTTGCGTTA GATTGGTAGA ATTATGGCTC CTTTTGCTGT CTTAATTTTT TCCTTTTACA TTTTGATACA TTATTTTAAT TTTAATTTTA AAATTCAAAA GAATTTGCCA CTCATCTTTG CCACTTCAAG GAAAAAAGAA ATGTGTTCGA TTATTCTGTT CTTAGTATAG TTTTGGCAAT TTCCTCACGT GTAAAAAGAG AATACTATTA ATAATTTCAG TATCTATAAG ACAATATAAA ATTAAAGAAT CTAGCCCAGT AACTGGTACA TGGAACGTAA TTAATAAATC ATTATGGACT TTTTTTCTCA CACCCAAGTA GGGAGGAATC AGTGGTCCCC TAGAGGCCCA GTGTAGAGGT GGCAGCACCA ATCCCTAGGG GAGAAGATCT TGGTGATGAT AATTCCTGAG CAGACAGTTA GCTGAGAATT CAAGAGCAGA AAAGTAAGAA

AGAAACAACT TCTTGCTAAC ACCTTTCCAC CCACGTTTCC CTGTTCTGTT GTACTCTGCT TACCCTTTCA TGGATGGAGG CAGAGGAAAG AGAACCAAGT TTGCTCTTAG TCATTCACTA TGTTGTTTAA TCTGCCTTCC ATCTTTCTTA TCAGTTCAAA TTAGAATGTA GACCTGAATT TAAATCCCCG TTCTGTCAGT TATAATGTGA CCCTAGACAA AACACATTCT CTGAACCTCA GAGAACATTC TTCATTTGTA GAATGGGAAG ATTAATCTAT ATTCCACTTG GATGGCAAGT CTTTTATAAA CTTTATAACC TAAACATGTG TGAGTTGCTA GTATCATTAT GTTGGTAAAG TTATTCTGAG ATATGATAAC AGAACTGTTT TGTCTAACTC CACTAGCATG GTTCAGGTTT AGAGAGTGTG GAATTAAAAG GCTTTATCCT CAAATATGAC TTAAATCCGA TTTTTCTCAT CCACTTTCCT CCACAAACAA ATCCTCAGGA AATGACAAAC TTTACATGGT TAAACATCAG TTTTGTTTAG

TCTTTGACAT CCACATGGTT AAATCATACA TTTGAAAACT GCTTATATTT GTGTTGTCTA TGTCTAAATT GAAAAGACTT ATTGAGGAAT AGAAGACTAC ACATTTTTCA GCAAACACTG CACGTTTTGC AGAATTTCCC CAGGCACCAG TCTCCAGGAA TTTATTGGCT ACTAACAATA CTAAGATATG GATGAATGAG GAAATCAAAA TGGAGATCTT GCAAGTTTTG TGAGAATGGG TGAATGGTCC AAATGAAGAG ATAAGTTGTG AAATATTAGT ACAAGTAAAA ATTATTTACA ATGAAAGACA TTTTGTCAAT AGCTATGAGA ATTTTACCAT TGACCCAGAA ATTCCATTTC TTTCTTCAGA AATACCCACG TAGGTATACA TATAAAAAGT TATTCATTAC AGTATCGTTT TTCATAGGAA AAAGTTTTAA AAATCAGAAG CTATCTAAAC TATGGTATAT CTAGGTCATA GAAATCAAAT GACTAAAAAT GTTAATATAA GCATATGTTT TTAAATTAAC TTGGCTTGGG TCTTCAGCAA

AATTGGCTTC TTAACATTGC ACTCCAGAGT TAGACTTACC CACTCAGTCA CTTATCATGC AGGAGCAGAC TCCTAATACC ACATATCATA GAGCAGAGTA GGACACAGGT TCTCTGCAGG CAGGCAAATC CCAAAGAGAA GGGAGGAAAG GGCTGAGACA CTGCATGGTC AATTTCTTCT GAACTCTGCA ATGTACGGAG GTGGACAGTG TCCACAAAGA TTGCTCCCCT GGACCCACCA TCATAATAAC ACAACGGCTT TGTTTTGTTT TTGTTTTTGT TTTTTGACAC GGAGTTTTGC TCTTGTTGTC CAGGCTGGAG TGCAATGGTG TGATCTCGAC TCACCACAAC CTCCACTTCC TGGGTTCAAG TGATTCTCCT GCCTCAGCCT CCTGAGTGGA TGGGATTACA GGCATGCACC ACCATGCCCA GCTAATTTTG TATTTTTAGT AGAGACGAGG TTTCTCCACG TTGGCCAGGC TGGTCTCAAA CTCTTAACCT CAGGTGATCC ACCCGTCTTG GCCTCCCAAA GTGCTGCGAT TACAGGTGTG

AGCCACCGCG CCCAGCCCAC AATGGCCTTT TGTTTACATC TCTAGTGCAG CACTCATTTC ATGTTCTTTC AAGAAGAATA CATATTTCAT CTTTTTATTT TATACAGCAA TTAGCACAGT GCCTGGCATA AGGAAAATGA TCATTAAAAG CTGGGTGAAA AACCTAATAA AGCTACTGAG GATAGGAACT GCAGACCAGC ATGGAAAGAA AACTATGAGC CAGATATTGA CATCATCCTG AAAGGCAGAA GATTTAGTAT AGGCAAGAAG TATGCTTTTG GAATATAGAA AATCTGGATT ATGATAAGAA AAGAATCATA TTTGTCTTAT CTTACCTACT CACTTCTCAG TTCCACATGT TTCTGAGGCT GTTTGTCCTT ACTTTCTTTT CTGTTTTATC CACTCTTTCT GTTCTTTAGA TTGGATCATT CCTATTGAGC TGACATCAAG TTAACTGACC TTTTATTTTG TCCAAACTGC TGTTAAATGC ATCCAGTGAA TTTTTAACTT TATATAGTAT ATCTTTTAGT CCTAGAATTT

CCACATGAGT TTTTTAAGTT TCCATTTCTC TGCTGAGATC TCCTATTTGT TCATTCATTA TGACCATATT TTTCTCTACA TTATTGAGCA TAATTATAAC AGCTCTTCTA AAATTCTTGT CTGCACATTC TAACACCTGA ATTATTCTGG GGTCAGTCTC TGTTACATTG CCTTATTACA AAAACAGTAT AAGTCACATT GCCTTGTTTC TTAATATGCA AAATGATTTT TGATTGCAGA CTAGACATTT TGAATTAAAC ATTATAGAGA TTCTGGATTC TCGAGAGAGT ATTGACTTGT TTTTTCCATC AGGCAGGTAA CTTGACTGGA CTCAAACTCC AAACTCTAGG TCCTCTGTAA TGGGCAACTG CAGTAATCTT TGTTTAGTTC TTTAAGACTT ATTGGCCAGG CACGGGGGCT CATGCCTGCA ATCCCAGCAC TGTGGGAGGC CAAGGTGGGA GGATCACCTG AGGTCAGGAG TTCGAGACCA GCCTGGCCCA CATGGTGAAA CCCTGCCTCT ACTAAAAATA CAAAAATTAG

CCGGGTGTGG TGGTGGGCGC CTGTAGTCCC AGCTACTCAG AAGGCTAAGG CAGAAGAATC ACTTGAACCT GGAAGGCAGA GGTTGCAGTG AGCCGAGATT GTGCCACTAT ACTCCAGCCT GGGTGACAAA AGCGAGACTC CCTCTCAAAA AAAAATTTAT TGGCACTGCT TGGCATCTGC TATGAATACA TGAAGTTCAT GGGTCAGCTA TAGATCTGGG CACGTTATAC ACAGAATTTG GGTCTCCCTT TCTCTGGATT TCTCCTTTTC TGGATTTCTT TTCTCATTTT CCAGCAGCTG TGGTTGCCCT AAACTCGGTC CTCTGTTTCT TTACGGCAGT AAGATTTGGG AACTTTTAGG TTTTACCTGC CTCTCAGACA AAATAAAAAA TAATTTTCAT CTTGATGCTA CTCCTTTCTT CCAGATGTAG ACACCTCTCT AATTTCCAGT TGCTTTTTAT TGCTCTCCAG AGTCTAAAGA TTATCATTGT TTTGTGTGGG AGAGTTGGTC TGATAAAAAC TACTCCCCCA AAACTGGAAG CTGGAAGCTT

GTAATTATGA ATAGACTTTG AGTAGTATTC TTCTTTGGAA AAGGATTTTA ACTACTCCCT ATGTACTTCT TTATTTCCTG TTTTTCTCAT CCGTAATCTT TTTATTTTCA TACTTCCTAA GTCAGACAAT TTTCCTACTT GAAGATTCAG TGACTGCTAT CAAATGACCC CCATATTACT AAATACAATA TCCCCAACTG CATTTATAAA AAGAAAATTT ACTGTTTATT AGTAAACAAT GTTGTAGAAT AGTAAAATAT TGCTGGGCTT TGGAGCCAGA TAATCAAGGT TAGAATCCCA GATTCTAACT TACTAGCTGG TGTATTAGTC CTTTCTCATG CTGCTAATAA AGACATACCC CAGACTGGGA GACTGGGTAA TTTATGAAGA AAAGAGGTTT AATTGACTCA CAGTTCAGCA TGGCTGGGGA GGCCTTAGGA AACTTACAGT CATGGTGGCA GCAAGGAGAA GTTCCAAGCA AAGAGGGAAA AGCCCCTTAT AAAACCATCT GATCTTATGA GAACTCACTC ACTATCACGA GAACAGCATG

AGGGTAACTG CCCTCACGTT TAATTACCTT CCACCAGTTC CCCCCCATGA CACATGGGGA TTATGAAAGC TATAATTCAA GATGAGATTT GGGTGGAGAA ATAGCCAAAC CATATAATTC CACCCCTGGC CCCTCTCAAA TCTCATGTCC TCACATTTCA AAACTCAATC ATGCCCTCCC AACTGTCCCC CAAGGTCTTA ACTCATTCCA GCATTAAGTC AAAAATCCAA GTTCAAAGTC TCATCTGAGA CAAGGCAAGT CCCTTCTGCC TATGAGCCTA TAAAATCAAA AGCATGTTAG TTACTTCCTA GATACAGTGG GGGTACAGGC GTTGGGTAAA TACACTGATT CCAAATGGGA GAAATTGCCA AAACAAAAGA GTTACAGACC CCATGCAAGT CCAAAACCCA ATAGGGCAGT CATTAACATT AAAGTTCCAA AATGATCTCC TTTGACTTCA TGTCTCACAT CCAGGTCACA CTGATGCAAG AGGTGGGCTT CCAATGGCCT TGGGCAGCTC TGCCCCTGTG GCTTTGCAGG GTATAGCCTG

CTTCCTGTTT GCTTTTTCAC AGGCTGACAT TGAGTGTCTG TGGCTTTTCC ATGAGTATGG TGCAAGCTGT TGGTGGATTT ACCATTCTGG GGTCTGGGCC AGGTGCAGTG GCTCATGCCT GTAATCCCAG CACTTTGGGA GGCTGAGGTG GGGGATCACA AGGTCAGGAG ATCGAGACCA TCCTGGCTAA CACGGTAAAA CCCAGTCTCT GCTTAAAAAA TACAAAAAAT TAGCCAGGCG TGGTGGTGGG TGCCTGTAGT CCCAGATACT TGGGAGGCTG AGGCAGGAGA ATGGCGTGAA CCCAGGAGGT GGAGCTTGCA GCGAGCTGAG ATTGTGCCAC TGCACTCCAG CCTGGGCGAC AGAGCAAGAC TCCATCAAAA AAAAAAACAA AAAAACCATT CTGGGGTCTG GAGAATGGTA GCCCTTACAG GACCACCAGG CAGTGCCCCA GTGGGGACTC TGTGTGGGGG CTCTGACCCC ACATTTCCCT TCTGCACGGC CCTAGTAGAG GTTCTCCATG AGGGTTCTAC CCCTGCAGCA

AACTTCTGCC TGGACATCCA GGCATTTCCA TACATCCTCG GAAATCTAAG CCGCGGAGGT TCCCAAACTT CAATTCTTGA CTCCTGTGCA CCCACAGGCT CAATACCACA TGTAAGCCAC CAATGCTTGG TCAGGGCTTG AACCCTCTGA AGCAATGGCC TGAGCTGTAC GTTGACACCT TTTAGCCTAG ACATCTAGGA CACAGGGCAC CATGACCCGA AGCTTCATAA AGTGGGAGGG CCTTGGGACT AGCTGAGGAA ACCATTTTTC CATCCTAGGC CTCCAGGCCT GTGATGGGAA GGGCAGCCAT GAAGGTGCCT GACATGCCCT GGAGACGTTT TCCCCATTGT CTTGGTAACT AACATTCAGC TCCGTGTGCA GCACCAACTT ACTTATGCAA ATTTCTGTCA CTGGTTTGAA TTTCTCCCCA GAAAACAGGA TTTTTCTTTT CTATTGCATC CCCCCAGATA

TCTCTCTCAA GTTCAAAGTT CCACAGATAT CTAGGGGACA AAATGTTGCC AGTCTCTTTG CATAGCAAGA GTGACCTTTA CTCCAGTTCC CAACAAGTTT CTCATCTCCA TATGAGACCA TCTCAGCTTG GACTTAGTTG TCCATGTTAC TATCAACATT TTGGTCAAAG CCATTCAACA AGTCTCTATG AAGTTTCAAA CTTCCCCATG TTTTCCTGTC TTCTAATAGC CCTCCAAATT TTTCCAACCT CTGTCTGTTA CCCAGTTCTA AAGTCACTTC TACATTTTTG GGTATCTTTA CAGCAGTGGC ACTCCCCATG GTACTAATTT ACTGTATTAG TCTGTTCTCA TGCTGCTAAT AAAGACTTAC TCGAGACTGG GTAATTTATA AAGAACAGAG GTTCAACTGG CTCACAGTTC AGCATGGCTG GGAGGCCTCA GGAAACTTAC AAACATGGTG GCAGCAAAGA GAAGTTCCAA GCAAAGAGGG AAAAGCCCCT TATAAAACCA TCAGATCTTG TGAGAATTCA CTATCATGAA AATAGCATGA GGGTAACTGC CCCCATGATT AATTTACCTC CCACAGGGTC CCTCCCATGA CAGGTGGGGA TTATGGGAAC TACAATTCAA GATGAGATTT GGGTGGGGAC ACAGCCATAC CATGCCAGCT AGAGAGCCTT AAGAAAGTCA CCTAATCTCC ACAAATAAAA GGTTTCCTAT TTGTTCAACA AAAATAATGA CACCCCTTTT ATGGGATTTC TGTGAGGACA AATGATAACT AACATAGCCT TGCATAGTGT CTGGCACAAA ATAGCTACTC AAAAAATAAT AGAAACAACA TTTAAAAAAT GTAGACTTTA TTTTTTAGAG TTTTATGTAC AAAGCAAAAT TGAGCAGAAT GTACAGAGAG TTTCCGTATA GCACTCCCTA CCCCCAAGCA CAGATAGCCT CCCCCAGTAT CAGCATCCCG CACCAGAGTG GTACATTTAT

TATAACTGAT GAATCTATAT TGACGTGTCA TTTTCATCCA AAATCCATAG TTTATATTAG GGATGCCTCT TGGTGTTGTA CCTTCTATGG GTTTTGACAA ATGTATAATG ACATGTATTC ACCATTACAG TATCATAAAG AATAGTTTCA CTGTCCTAAA AATCTTTGAT CTTCTTCCTA TTCATCACTC CCTCCCCATT AATCCCTGAC AACTACTGCT AATTTTCCTG TCTCCATTGT TTTGTCTTTT CCTGAATGTC ATATAGTTTA AATATACAGT ATGTAGGATT TTCAAACTGG TTTATTTCAC TTAGTAATAT GCATTTGATG TTCTTCCATA TCTTTTCAAA GCTTCATAGT TCAATATTTA TAGAATTGAA TAATATTCCA TTGTCTGGAT GTACTACAGT TTATGTATTC ATTCACCTAT CAAAGAACAC CTTGGTTGCT TCCAAGTTTC AACAATCATG AGTAAAGCTG CTATAAACAT CTATGTACAT GTTTTTTTGT GAATTGAACA TTTTCAGCTT TTTTAGCTCC ATTCCTAGGA

GTGCAATTGC TGGATTGTAT GATAAGGGTA TGTTTAGTGT TGTAAGAAAC TGCCACGCTC TTCCTAACTG GATGTACTGT TTTGCATTCT CACCAGCAAT GAAAGAGTTC CTGTTGCTCC ACATACTCAC CAGCATTTGG TGTCGTCAAT GTTTTGAGCA ATAGCATTTT GATCTAACTT TTCCTAGGTA TTCTTTTTGA AGGAAATAAT ATGACAGATA ATAGAGAAAG GATATACGAG GACAGTTCTG TCCTTTATTT ATAGTCCATC ATTTAATGAA GGACTCTGTC CACACTTGGT ATTTTTAACT CTGATCCTCC TCTCCCATGA ACTCTGACAA TCTCCTAAAT CCCTGTTGCT GGCACACATG GTTGTGTATC AGGCCCCCTG TGGTCTGTCT GAAGCATGGC χχ_Tχχχχχχ_{T τττ}χχχχ_TTχ ACGGAGTCTC GCTCTGTCGC CCAGGCTGGA GTGCAGTGGC GCGATCTCGG CTCACTGCAA GCTCCGCCTC CCGGGTTCAC GCCATTCTCC TGCCTCAGCC TCCCGAGTAG

CTGGGACTAC AGGCGCCCGC CACCACGCCT GGCTAATTTT TTGTATTTTT AGTAGAGGCG GGGTTTCACT GTGTTAGCCA GGATGGTCTC GATCTCCTGA CCTTGTGATC CGCCCGCCTC TGCCTCCCAA AGTGCTGGGA TTACAGGCGT GAGCCACCGC GCCCGGCCTT χχχχ_TTχ_{TTT TrnTrTTTT} χχχ_GAGATGG AGTCTGTCAC TCTGTCACCC AGGCTGGTGC AGTGATGCAA TCTTGGCTCA CTACAACCTC CATCTTTCAG GTTCAAGTGA TTCTGCCACC TCAGCCTCCC AAGTACCTGG GATTACAGGT GCCCGCCACC ACACCCAGCT ATTTTTTTGT ATTTTTAGTA GAGACGTAGT TTCACCATGT TGGCCAGGCT GGTCTCATTC CTGACCTTGA GTGATCCACC TGCCTTGGCC TCCCAAAGTG CTGGGATTAC AGGCATGGGT CATCACATGT GGCCTGAAGC ATGACTGTTG CTTTAATCAT ATGAAATACT GCTCTGTATT GTTATCTATT TGAAATGCCA CACCTCCTGA

GCTAAATTGC AAGCTTTTAT GGAGCACAAA CCATATTTAT ATATATTAGC ATGATACCAT GACACATATC AAAAGCTGTT ATATATTGTT ACGTGAATTG ATTCTTTCTC AGTTAAGAGG ACCTCTGTAG TAGCACTTTC ATACCGTTAA TTTTTCATTT TGTGCCCAGC CCCTACTCTG TGAAAAATGA AATGAATCCT GTTATCATTT CCCTCCCAGG CCTTTTCTCC TTGTGGACAA TGTGTGGCTC AAGAGAAAAT TCAGTCAGTA AATTTGTTCA GTGCACAAAC TCTTTATCAC CTCTCACTGT TCTCAAGTGA GATAGAACAG AACATCCATC CAGTGTCTTA CAAATTGTCT GGTATATAGT AGGCACTCAA TAAATGTTTT TTGAATAAAT GCATACATGA ATCCTATTCC TATATATAGT ATGGTAGACA GATCATTGAT ACCCAAAGAT GCCCAAATGC TGATCCCCAG AACTTGTGAA TATGTTACAT TTCATGTCAA AAGGGACTTT GCTAATGTGA TTAAGGATTC AGACCCTTGG

ATTGTAAGAT TATCCCGGAT TAACCAGGGC CAATCTAATC ACATGAGACC TTAAAAAAGC AGAAAACATT TCCCAGCTGG GTTAGAGAGA GATGAGACAG AGTAAAAAGG AAAGAGATTC AGGGCATGAA AATGACTCTA CCCACTGTTG CTGGCTTTGA AGATAGAGGA ACTAGGCCAC AAAACAAGGA GTATGAGTGG CCTTAAGAAA TAGGAAAAAG CCCTCATCTG ACAGCCAGCT AGAAAGCAGT CCTCTGACCA CAAGAAATTG GATTCTGCCA ACCACTCAAA TGAGCAAGGA AATGGATTCT CCCCTAGAAC CTCCAGAAAG GAACACAGCT CTGTAATGCC TTGATTTTAG CCAGGTGAGA CCTGTTTCAG ACTTTTGACC TATGGAAATA TAAGATAATA AAGTTTTATT GTATGCTGCT AAATTTGCGG TAGTTTATTA CTGAAGCAAT GGAAAGCCAA TACAGACAGA ATATACAGAG AGAAAGAGAA TGAGTTCTTT CCTGATAATT TGTAAATATT TGGGTCTTCA

CTGGACAAGC TTCACAGAGG ATTCACTGGT TCCCTAGCAA ACCAGCATGT CCAGTCCTGC AGCCTCCCTT TCTTAGGCCC AGCATATGTC AGCTGTGTGC ATAGAAAAAT CAAAGCAGGA CCCTGAGTAG TTGGAAAGAA AAGATGGTTG GAAATGGGTT GCACTTCAAG TGAGGAAACA AGAGGTAGGA GACCGGCATC TCTTTCTCAT ATGTCCCAGG CTGACTCTTG TGAGTTGTTT TCCCTTGGAG GCTATCGATG ACAGTCACAG TAACCTGATG GAACCTGGAT CATGATGAAA GAAGTAAGTG TCAATGGCTC CGACTTCCAA GGACTCTGAT GTCCCACAGC ACTAGCTAAA CAAAGCCAGT TGGAAATGAG CTTAAATGGG GAATTTCCTG AATATATTCC CTATTGTTAG GAAGCCAGGT TGGCTTCCTT GCCTACAATT ATGCCAAGCA GTCACACTAT AGAGTCCCTA GGGACATGAT ATTAAGTGAT TCTTTTAACA CAAACAACTT AATAATCATT TATACTAATA

GCAAAACGGC CAACGGCTGA TATTCCACTT GAAGTAGAAT TGGCTATCCA ACTGGAAGAG AAGACAGGAA GACGTGATCT CCAGGGAGCC ACTAAAAGGA TTGGCACCTG CCTCTGGATT CCCCTTTTCC TTATATTACC TCTCAGCACT GGCAGGCCTT TATTTCAGGA TACAGTTTCA CAAGTATTAT GTCACGTCTC TGAGAATTAT GTTGGTAGAT ATTTGCTCCT CTGGCCAGAA AGACCTAGTT TGGAGTCTGG AGTCATGAAG GTGACATACA TGTAGCTAGT GACATAAGTG TAGCTAGTAA AAATAGTGAG TAATGGCCCT GAAATTCTAT TGAATGCCCA AAGTGCTGAC CAGGAACAAG CATGCTCTAG CTTATCTCAC AAGGAACTTG ACAATTTTCT TCAAAAATCC TAGTAGCTAA GATTTCTTAG TAACAAAGCC ACTAAGGCAC AATTATGATT AACTTGACCC TTAGGTGACT TTTAAGGACT ATTCTATAAA ATATTACAAC TAATAGTGGA TCCAAGCCAG

CACACTCTGC TATATAAGAT TAATTGACAG TGTCCACACT GGTAAAATAA GTTGTTTCAT AAATACATTA GAATTCATTT GCACTTTCTA CACAGCCCCA AGTCCAGAAC TTTCCCCAGA ATAGGTCTAT GTTTTGCAAT CTGCTACTCC ATACAGAGAT TTGAGTTCAC TTGGCAATTT AGTGCTGCTT ATATGTGACC AGTTAGTCTG TTTTACTTAT CTATGCCTTA AACATTACTA TACTTACTAA CTCCAAGATG CCTGGTCTCA ACTTGACAAA AATACCCCAA GTTGGGAAAT CCTTATGTGA ATATGTAGAT AGTCACAATT GCTGGTTGAT GATGATCTGT CTTTTCCTGT ATTTGAGAAA ATGGAGATAA AATGGACCAA TCCAAATAAT GGATTAAACA TGGGAATAGG TGAGAGAGAG AGAGGAATAC ATGGTGGCTC TCAGTGTCTG GCTTAGGCAG TAAACACTTT CGTTAATAAA GACGGAAAAT AAAAAAGGAA TAATTGGTGT CTAGGGGAAA ATAATGAGCT CAAGTTTTAA

CACTCTGAGT TCCCGGATGT GAGACATCCA GGCGCATTTA TCCAAGAGGC AGTTGGAAGC AACGTTCCGG AGCTTAGGAG AGAGGCATGA CCAAAAGCTG GTGGGACTGT GAAAAGGTAT GGCCATTCTG GAAAACTGTT TGGCAGTTTC TTAGAAAATT AAACATGTAC TAACAACCCA GCAATTGTAC TCTTGAGCAT TTGTCCCAGA TAAATGAAAA AAAAAAAAAG CATTTTTTTT ACACAAAAAC ATATACATGA AAGTTCATAG AAGTGTTATT CATAAAAAAC TGGAAAAAAC TGAGATGTCT TTATTGAGTG AATGCTTAGG CAAACGGTGG TCTATCCATA CAATGGAATT ATGCTTAGCA ATAAAGAGAA AAGAACTATT GATACATGCA ATAACACAGA TGAATCTCAA AGGAATTAAT GCTGAGTGGG AAAAAAAGCA CATCTCAAAA TGGTATATAC TGTACTATTT TATTTACTTA ACATTTTAAA AATAGCAAAA TCATAGAGAT GGAGAACAGA TTAATGGGTA CTGTGTTTTG

GGATGGGGAG TGAGAAAAGG GTAAGGTGTA AATATAAAGG GGTAGCACAA AAGAGCCTTG TGGTTGAAGG ATTCTATGTC TTGGTTGTAG TCGTGATTGC AGGAATCTAC ATGTGATAAA ATTGTATGGG TCTACATACG CATACACACA AGAGCATATA AAACTGGTGA CATGTGAAGA AGCTCCGCAC ATTGTGCCAA CATCAGTATC CTAGTTTCAA TATCAGACTA CAGTTATACA AAACATTGTC ATTGAGGGAA ACTGGGTAAA GGGAACACAG GACATTTGGC ATATATTTTT GCAATTTCCT GTGAATCCGT AATTATTTAA AAATAACAGA TATACTACAT ATCAAAAATT TAATGTCATA AAGTTGATGA GTTTACCTAG TGGATAGCTT TGTTAATATC TGCTATAAGA CTACTGAAAA TGACAGTTAT GCAAGTATAA GCTCAGAGAA CTTTCCTCCC CCTTCGTAAA TGAAATGAGC AAAAGAAATG AAACAGGAAA GGCAAGCAGT ACTGAAAACA GGGAAGGGCT CTTCCCCATA

TAACTATATC TGCGACTTCA ACAGCTATTC ATCCAGAAAC ACAGCCTCTT GCGCTAAGAG GAAACTTTGG ATAACAATAT GTTTTCACTC TCCAAGAGAG AAAATGGATA GATTAATTTT TAAGAAAAAA AAAAAAACCT CACCAATTTC ATGCTGTGGC TTGCACCTTT AATCCCAGCT ACCTACAAGG CTGAGGTGAG AGGCTTACTT GAGCCCAGGA GTTCAAGGCT GCAATGAGCT ATGATTGATT GTGCTATCGC ACTCCAACCT GGAGTACTAA GCTAAGAGCT AAGAACACAG CTGAGAGCGG AGAAGAAACA AACAAATCTG ACCAATAACC CCCACTCCCC TCATTTTACT GGAGTGAGCT GAGACTGCTG GCAAACATGG CCTTTGACCT AGCCTGAACT GTAGCAAAAG TCATCAGATA TTTTTCCACC AATCAACAGA CAGAAGTGGG GAGAAAACAA TCGTAGTTCA TAACTACAAC AAGCAGATAA ACGAAGGCCA TGGTGAGGGA TGGAAGACAT TGTGATATAT

CAAAGGCAGG CTCATTTAAA ACTCAACCCA AATTCCAAAC AAAATATATA ATTGAATATG TATTAATGCC AAAGGAGCTT GAGTGAGCTT TAGCACAAAC CCCGCCCTCC AGCCCCCACC CAAAAAAATC ACTCTGTTCT CTCCCCATTC TTTGATAGGC ATACTTGCTG TTTTCTCACA GCCAAGGTAC AGAGGGGACT TAGAGGAACT AGAACTCTAA TACACTGCTA GCAGGAATGT AAAATGAAGC ATCTACTTCA GAAAACCATT TTATCAGTTT CTAGAAAGTT AAACATAGAC CCACCATGCA GCCCAGCCAC TCTACTCCTA AGTATTTACA CAAGAGAAAT GAAAACGTGT CCCCACACAG TTGTATTTAA AGGTGATGGT TAGCCTTGTG TGTCAACTTG GCTAGGCTAT AATACCCAGT TACTGAATCA AATAGTAATC TAGGTGCATC TGTGAAGGTA TTTTGTAGAT GTGGTTAACA GCTACAATCT GTTGACTTCA AGTAAAGGAG ATTGCTCTTG ATAGTATGGG TGGGCTTCAT

CCAATCAATT GAAGGCCTTA AGAGCAAAAA GTAAGGTTTC CCGGAGAGAA AGAAATTCTG CCTGAAGACT GCAGCCTCAA CTCCTGCCTG AGTTTCCAGT CAGCCAGCCA GCCTAAAGAT TTGCTAGGCA TTATAATCAC ATCAGCTAAT TTCTTAAAAT AAACCTCTTT ATATATATTG ATACAATGAA TGGTTATAGC AGCCTTATTT GTAATAGCCA CAAACTGGAA ACAACCTAAA TGTCCTTCAA TAAGTGAATA CATAAACAAA TTGTGGTATA TCCACAATTT TTACGCAGCA GTAAAAAGGA ATAAATGGTT GAATAAGGAA TAAACACATA ACAAGGATGA ACCTTAAAAC CGTAAGGCTG AATGGAAAAA GTCAGACAAA ACTAATACAT ACTGAATAAT TCCATTTATA TTGAAGTTCT AGAAAATGAG GACTAACCTA TAGTAACAAA AAGCAGAAAA ATTTTGCCCA CTGGTGATGG AGGGGGCGCA GGTATTGTAG AGTATCTGAG AAAGGACAAC TGGATAAAAG

GGGGCACAAG AAAACTTTTG AGGGTGATTG ATATGTTCAT TATCTTGTGG CATGGTTTCA TAGGTGCATA CATATGTCAA AACATCAAGT TATACACTTT TAAAATGTTC AGTTTACTGT ATATCTATTA TACTTCAGTA GAGAGGAAGG AAGAAAGTGG GCAGGGTGGG GGAGAGGAAA GGAAACGAGG GAGGAAAGGC CCTAATAGGA AGGATTTTGG AGTTTAGATT TTAAAATGAT AAAGGATGTT TGACACTCTA GGCATATGAC GAATATAGGA TTATGAGTCC ACAAAAACCA CCAGGAAGTC ATGTATGTTT ATACTTTTAA GTGAAGGATC AGTGGATTAT CAACTCCCTA ATGCTTTGCC TCTCTATGAC TGGCTGCTGT CCTTCTCATC CCAATACTCC TTCCAAAGCC CCTTGCTTAA ATGTAAGCCT TCTTTCCTCC TTTCAACACA TCCTGCATTC CGTGACAAAA TAAGTTTTCC TTAAACAGAA TGTACAGCAT ATTATTTGTA CAATTAAAAA TTTTTGGCCA

GGTGTGATGA CTCATGCCTG TAATCCCAGC AATTTGGGAG GCCGAGATGT GTGGATTACC TGAGGTCAGG AGTTCGAGAC CAGCCTGGCC AACATGGTGA AACCCTGTCT CTACTAAAAA TACAAAAATT AGCTGAGTGT AGTGTGGCAG GTACCTGTAA TCCCAGCTAC TCAGGAAGCT GAGGCAGGAG AATCGCTTGA ACCTGGGAGG TGGAGGTTGC TGTGAGCAGA GATCAGACTA TTGCATTCTA GGCTAGGAGA CAGAGTGAGA CTCGGTCCCC AAAAAAAAAC ACATTTTTTT TTAATGTTTC CTCCTTGCCT GTAGGAAAAA GGCTCTGACT CCTTAGCCTG GGCATCAGAG CTCTATCTAA ATGGACTTTA ACCTGATTTT GTGGCACTAA TTCCATTGCA GTACTTGTCC GCTCACTGGC CTGTGCCTCT CTGCCACTAT TTTTGGAATA ATGTCCTCTC TCCATCTTGT TTACTCAACT ATATCCAACC TCTAAGGCTG TGCTCCTACA AAGCCTCCCC TGGCTACTTC AGCCCACAGA

GATATTTAAC TGCTCTGCAG TTCAGGACAT TCTTCTGACT CTTTAAATCA CATTTACTTA TATATGATCT TGTGATATTT TTTGTTGACG TGTTTACTTT AATTTTCTTC CATAACCTAT TCATTCAACA AACTCAACAA TTATTTATTA AATGCCAAGT TAGAAAAATA TTATTGATTT TATATAGATT ATAGATATGT TTGAAATTTT ATTTGGCAAT CTGCAAGTAG AAAAATAATT ATAATGTGGT ATATCTGTGA TAGAAGTATT AGTGCAGAGA CCATGGGGAA CATAATCCAG CCTGGAAGTT CAGGAGAGAT ACGTGGAAGA AAGGACGTCA GAGCCTTTTT CCTACAGGCA TGGAAGAAAC ATTAAAAAAA ATTTTTTTTT TTGAGATGGA GTCTCACTCT GTCTCCCAGC CTAGACTGTG GTGGTGCGAT CTCTGCTCAC TGCAACCTCT GTCTCCCGGG TTCAAGTGAT TCTCCTGCCT CAGCTTCCCA AGTAGCTGGG ATTACAGGTA CCTGCCACAC ATGGATGATA AATATGATCA

TATTTTCTTG TTCTTTTCCT CCTCAGTTGT CTTCCCTGAA GAAAGGAATG CCTTTTATAG ATGACAAACT CCCATTCTCA AGAACAAGGA TTTTTGACCA ATTTAATTTA ATCAGATGTC TGGCTTTGAC CTAGAAACAC AGTCACGAAA CTTGGTGATT AGAGACCAAT TCCCAAACAT GAGCATTTCT TAGGAAACAC AGTAAAGATC TGAGAGACCC AAGAGCAGAA GGGCGAGAAA CCAAAAGCCA TCAGTTTGCA TAGGAAACAC CTTGTTTAGC CTAATCTTTT TATTTTTATT ACTCTATTAG TCACTACAAC TATTTTCTGA TTGCTATGGT GATAGATGGT TTAAAACAAG CCTTCATTAA GAATTGTCAC ACCATGGTCT CAGTCAAAAA CACCAACATT TTTATTGGTA TTGACAATTA TGGGAATATC CAATTCCAAG AAGACAAGGA GACCTCTGAA CTTTCTAAAT GAAGACTCCA ATCTTCCTGA TCTGATGGGA AGCAGCTTGG CAAGATTACC AACCACCACC ACAGAGAGTG

GACTCTAAGC TAAGACTTAA AAGATAAGTA GAAATTATCC AGGTAAAGAT GTGTACAGAG AAGGAAGTAC ATCCAGGGGA AAAGAACAAT ACGTGCAAAA GTACGGAAAT GGTAAAAAGT AATACTACAT AGTCAAAGCC AAGCAGAGTT CAGAAGGGAT CTGGTGGTGA AAAATACGGC TAGAGAAAGC AGCAAGGATT GGCTTCTAAA ACCTATGTAG TATCTTGGAC CTTACCCTAA ATGTAATGAG AAGCTTCTAA AGAATCTTTC ATTTATTCAT TCATTGAACA AATATTTTGA GGCTTTCTGT GAAGAACATC ATTCTAAGTA GTAAAGATAC AGCAGTGAAT AGGACACATA AAATCCTAGA TCTCACAGAA TTGACATTCC AGAGAGGGAA AGGTAGACAA TAAATACATA AACAAATCAT TTAACAAGAT GATTTCAGAC AATGGTACGT ACTGTGAAAA AAATGAAACA AGGTAATGGA CAGCGAAAAG GCAGTGGAAG GAAGCCTGCT TACCTTTGCA

TGGTTAGAAA AGATCTCTCT AAGAAAGAGA CCACATGTGA GCTGCGACCT GAAGGATACC GAGAAGCTAG GTGTGCAAAG ATGTGGGGAC AGAACTTTTG GACTGAATAG CAAATACAAA TGCCCTTGGG TGCAAGCTTT GCCTGTTCAA GGACCAAAAA GAAGGCCAGT GTGCCTGCAG CATACTAAGC ACAGAGGAAA ACACTGTTAT ATGCTGAGAT TGGAATTATA AGTAGAGCCA GATAATATAG TCTCTTATAG GTCATAATAA GGCAACCAGA TTTTATTCCA AGAGGATTTA AAAATCACTG GAGGTTTTGC ACTAGGGTGA GAGGTGTGAT TTGTATTTTT AAAAGATAAT TCTGGAGAAT TAACTATAAT GAGGTAGGAG TAAACTAAGT TAGGGGCTAT TTCAGTGGCT CAGACAAGAG ATAATGGTAG CTTAGACTAG GATAGTAGTC GTAGAAATAA ATAAAAGTGG CACTCTACTT TGGGGGTAGA GTCTATAATA GGTTTGGTTT ATGGATCATA TATGAGAGTA AAAAAAAGAA AATAAATTAA TAATGGTTCC TAGGTTTGTA CCTGAGCAAC TGAATAAATG GGTGCTGTGA ATTGAGATAA AGGAGATTGA GAATCACAGG CTTTGTTTTG CAAATTAATT TTGAGAGGCT TATTAGACAT CCCAGTGGAG ATTTCAGGTG AGTGGAGCCC ATTGAAAGGT AAGGGACAGG GTCAGGTGTG GTAGGTCAGG CCTGTGATCC CAGGACTTTG GAAGGCCAAG GCAGACAGAT CAGTTGAGCT CAGGAGTTTG AGACCAGCCT GGGCAACATG GGAAAACCCT GTCTCTACAA AATATGCAAA ATATTACCTG GGCATGGTGG CATATGACTG TGGTCCAAGC CACTTGGGGG GCTGAGATGG GAGGATCACT TGAGTACAGG AGGCGGAGGT TGCAGTGAGC CAAGATCTCG

CCACTGCAAA CCAGCTTAGG TGACAGAGTG AGAACCTGTC TCAATAAATA AATAAGAAAC GTAAGGGAAA AGGAAATTAA TCTGATCATT GGCAAATGCA TAGTATTTAA AGCCAGGGGA GTAGATGAGA TACTCAAAGT AGGTGAAGAT AAGGAGGCAA TGAAGGCCTA GGACTCTGGT GTACATTTAG ATGGTTATAA GAGGAATAGA AACTGGCAAA ATAAGTAACA CTGAGCACCC AATGAGGTGG AGAGGAAAGC CAGGAGATGA AGCATCATAG AAGGCAAGAG AAGAAGGGTG TCAAAGAGGC GAGGCAGTCA TCAACTTCTG GGCAGTCAAA TAATATAAGG ACAGAAAAGT GACCATTGGA TTTGGAAATA TGATGAGCAC TTTGAGTGGA GTGTTGAGAC AGAAGACCAA TTAGAGTAGA TTGAGGAGAT AACGAGAAAT GAGAAAATGT AACCTGCAAG CACAGACAAT TCTTGAGAGA CTTTTCTGTG AAAGGAAACA GACACAGAGT CTTAGCATGT

CTTGTCTTTC TATGGGAAAT GTAAATAGTT TGAGATCAGG GATAGTATTT TATTCTGCTT TTTGTACCTC TACATTACCT AGCATAGAGC TAGCTAATGT GCACTTAAGT ATGTTCTCAA TTCTTATCGC CTGAATGACT GGATGGGTGA AAGAATGGAT GGATGGATGG ATGGATGGAT GGAAGGATGG ATGGATGGAT GGAAGACTTC TGATTTGCCA AGAAGAGGAT ACTGGTAGCA GAAATAAAAA CAGCACTGGA GAAAGAAGAG TTTAGATTTT TATTCTTTGG TGTCAGTTAG ACAGGAAAGT AAGACATTAG AAGAGTCCTT AGATAATTTA TGTAATTGTT CACTTAGGAT TTTTAAATGT GATCACTGAT ATTGGACATG TTCCTAGTGA AGCATTTTTG GTGTTTCACT GGTTGAAGTT AATAACTGTA AAATTATTTC CCGTTCAGGA CAGAAAAACA GAAAACTTGA AGCTCCTATT AGAAAGTTCA AGATTCTCTG GGGTTCTTAG GATTTACTGT TCCCAAAACT CTGTCAAGAA

CAAGAAAATG ACCTGTATAC TTAACTGGTC TAGGCAACAG TGGAAAGACA ATTCTCAGAG AAGATTTGTT TTAAGAAGAC ACTTTCCATA GGAATCAAAC AATAGCTTTC AGTGACTAAC ATGGTAAGAC ACAGGGTGTT AGCTCTTTCC TTCCAACCTC ATGGCTGTTG TACCTTACCT TTCGACCCCG TGTTCCTGAA ATTGTTAAAT TCATAAACTT ACCAAGGACT AACCAGCCTC TGGGGAATTG CTGTATACTT AGCAAACTTA CAATGGACAT ATTTATAAGC CATAATGATA ACTGACTAAT AGGAAATACC CTCAACTGAA AATGAGAGAT CATCATTTGC AAATGAGTTC CCTTGCCCAG GCAACTACTG GGGAAAATGT CATGCAAGCA AAATTAATCT TTGAAATCCT CCTTTTCCAT TTTTTGTGTC TTCCTTTTCC ATAGGCACCA GAAATATCAT GGTGCCTGGA TCTCATCTCT ACAGAAAAAA AAAGTGATTT GATAAACTGA TTTATATTGT GTCCAAATGT GATTGTATTT

TCAAAGATAA CCTAAGGGGA GAATGCTGTC TGGCCCAACA GCAGGCTCTC GACTTCATTT CAGACACTGT GGCCAATGGC TGGGAAACAG GTATGAACAG TAGGTTTCTG AGTCCCCTGG AATTATTCCA TTTATGTAGC CACCTCCATG ACAGGAAGCC TCCCTACTCT TACTTCCCAG TTTGTTCATT CATGGCACCA GGTTGCAGAT TAAAATTTGC TCAGTGACCT TTTATCTAAT AATGTGTTAC CTTCTTCTCT TAAAAAGTAC AAGGGACAAA TGCTCATGGT ATACTTTTAG GAGATTGTGG CTCTCTATTA ACAGTATTTA TTCAACAAAC ATTTATTGAG CATTTATATG TGCATCATGC TAGGGACTGG AACCTAGTAA GTGTAGCACA TATTATTTCA TTTAATCCTC ACAACAAACC CATGAGGTTG GTTTTATGAT CCCAATTTTT CAGAAGAAGA AACTGATATT CAGAACCAGT TAACTAACTG GTTCAAGGTC ATGCAATTTC TAAGATACAG AACCAAGAGT CAAAGACATG

ATTTTAAACC AAAGCTTTTT CTGCTACTCC ACATTGCTTC CCTAGGTGAG ATCTGAGGCA TTCCGCGAAA AGAGAAGGGT CATAAAGCCA AGGGAAGACA AGCTTAGGAA AAAAAAGGGA AATGTCCTAA ATAAACAGCT TTCCTATTTA CCAGAAACCA CTAGTTTAAA AATATAATGG GAAAAATCCT ATTCACTTTA ACAATGTTAA AAAAAAAAAA GATAGAAGAA ACATAGGGAT AAACTTAACA CATTTGTAGG ATATGTAAAG AAACTAAAAG ATGTTAATAA TGGCCTAAAG AAAAAAAAAC TTACATGTAT GGGGAGATAG ACCATCTTAC TGGATTCTAA TATTTAATAG TCTAGGTGTT CCATTTCTCA CCAAATTAAT GTATACATTT AATACAATGT CAAACGAAAT ATCTTAGGAA TTGCTTACAA ATTGTCAGAT AATTACAAAG TTTACCTGGG AAATATAAGC ATATATGAAG AGTGAATGGG ACCCCACCAC TCCCCCCAAA ACAAAAAAGG TCTGAAAAGG

ACAGAAATCA AGGAGAGTCT TGCCTGCCAG ATACAAAATT CTATTATAAA GGTGTATTGA TGAAAACAAT TTAATACTAG TGTAGCAATA GGCAGCAAAG CAATGAAACA GCATAAAAAG ACCAGAACTA TACCTAATTA TGATGAAGAT TTAAGGTATG ATAAACATGA CATAATTCAA ATCAGCAGAA ATTGGCATAG ATAGGGTTAA GACAAATAGC TAATCATTAG AGGGGAGGAA GGAAAGGAGG GAGGATAAAA TTAGGTTCCT GCCTTCATCT TACATTAAAA TAAATTCCAG ATGTATTACA TTTAAATTTT TTTAAAAAAA GAAACCACAA AATACTTGAA GAAAATATAA GTTGTTATAT AGTCTTTTGA TGGGAATTTT TTTTTTTTTC AGAGACAGGG TCTTGCTCTG TCACCTAGCC TAGAGTGCAA TGGCATGATC ATGGCTCACT GCAGCCTTGA ACTCCTGGGC TCAAGTGATC CTCCCAGCTC AGCCCCCCAG GTAGCAGGAA CTACAGGCAT GCGACACCCC ATCCAACTTA

_{TTTTTTATχτ TTTGTAGAGA} CAGGGGTCTT GCTTTGTTTC CCAGGCTTAT CTCGAACTTC TGCCTTCAAG CACCTCAGCC TCCCAAAGAG CTGGGCTGAT GGGACATTTT TTAACATAGT GCCACATTAC CATAAATGAA AAGCTTGTAA AATACTAATT TTTAAAACTA ATATATATCA GAAATTTTTA TAAACAAAGT TAAAAAGCAA ACACAAAAAA TTTGTAGCAC TTATGACAAA TATATGTATA TATATGAATA CAAAAAGAGC CTTTACAAAA CAGTAAGAAA ACAATGAATA CTCCCAATGG AGTATTCAAA ACTAAACTGC TAAAAGCAAT TCAAAACAAA AAACATAAAC TATGCATATA TGTATGTGAA AAAGTTTAAC CTTATCAAAG AAGTAAACTC TCAAAGAAAT AAACATCAAA TAAGGAAATA GCCTTTTCCC ACAAATAACC AAAATCTGTA AGAATACTGA GCTGCGAATG TTTCAGAAAA AAAAAAAAAT CATACACCTA GTTCGGCATG TAATTAATAT AGATCAGAAC

ACTTTAAAAA TATTTATAGG CCAGGCACGG TGGCTCATGC CTATAATCCC AGCACTTTGG GAGGCCAAGG CGGGTGGATC ACCTGAAGTC AGGAGTTTGA GACCATCCTG ACCAACATGG TGAAACCCTG TCTCTACTAA AAATACAAAA ACTAGCCAGG CATGTTGGCG TATGCTGGTA ATCCTGGCTA CTCGGGAGGC TGAGGCAGGA GAATTGCTTG AACCCAGGAG GTGGAGGTTG CAGTGAGCTG ACATTGTGCC ACTGTACTCC AGCCTGGGCA ACAAGAGCAA AACTCTGTCT CAAAAAATAA TAATAAATAA AAATAAAATA TTTATATACT CTGACCCATC AATTTGTCCA GCATAATTAG GCATGTGTAC AAGGGTTTAC ACACAAGAAT GCCTATTGCA ATATTGCTTT TAATGCTAAA AAAAATTGGG GAAAATGCTT TAAAAATATA GATTAAGACT GTACATTGTG GTACAGTCAT ATAATCAATA GTATACAGCT ATTATTTATT TTCAGCCACT GTCCAAAATA TAGCCTGGCC

TAACAACATT CTGTTAGGAT ACGCAAGCAC CGTGAGGAGA TCAGCTATAA AGTATCAGTG TTTCACACCA CTGCTCCTTT GCTAATAACC TTCAATGGCT TTTAAAGAAG TAAAAAACAA AGGCAAAATT CCTTAGTCAG CCCTTAAGAC TCTCTGTTAC TTAGCTCAAA CTACCCTTTT CAACAACACT GCCCTAACCA GGATGAGTTT TTTGCCCCCC TGGAGTACAT TCAGCCTTTC CTTATCAAAC CTTCCTTTAA ATAAGTATCT TCTCCAOGAC CACTTCACTT TCTTCCCCAA TTTAGCATTT TCTATATCTC CAGGCCTACC TCTATAAAGC CTGTCCTAAC CACTCAAACC CTAGCTTTTT CTCTGAACTG CTAGAAATAT TTTTCTCTCA TTGGCCATTT AGGTAAAAAG GTTTTTACTG TTTATTACCT ACTCAATAAA AATTTTCTTT TTTTGAGACA AGGTCTTACT CTGTCGCCTA GAATGGGGGG AAGTGGTGTG ATCACAACTC ACTGCAGCTT CTACCTCCCA GCTCAACAGT

CCTCCCACCT CAGCCTAGTG AGTAGCTGTG ACTACAGGCA TGTGCCACCA TACCCCACTA CTTTTCATTT TTTATTTTTT GTGAGATGGA ATCTCACTAT GTTACCCAGG CTGGTCTGCT GATCTCAATT GATCCTCCCA CTGTGGCCTC CCAAAATGCT GGGATTACAG GCATGAGCCA CAATATCTGG CCCCAGTAAG CTTTTAAGGC CATTAACATG AGGAACAGTG TTCTTTACAC TATTTTATCA GCTAGGGCTT TGCATGGAGT AGGAGTTTAG TAAATGCGGT TGATGGGTTA ATCAATGTGT GAAAATATTC AGAGCCACCA AAAACAGATA TTATGTCTAT TCTCATCAAC AATCAAAATT GAGTAAACAG CCATTTTCTA ATACAGGAAA CCACAAAACA TTGAATGGTG ACATTAAAAA ATTCCCCCAG CAGGAGCCAA CCAATTTTTT CATCCTGATC CAAGTTAGCA AACTGCAAAA GATAGGAAGC ACTAATGAGT GGAAATTTGA GTAGAAGCAT TTCTTATGAA GGCTGTCTTG

ACTGGATCAC ATTTTTATTG CTGTTGGAGG TGCCAAATGT GTGTGTTTAT GCTAATCCTC CACCTCAGGC AACACACAGT CAAGGATCCT ACCAAGTGTT ACCGTCAAGT GTCTGTTGGC AGCTCAAGGC CCCAGCGTTG TTCCCTTGCA CTAGGGAAAA GACATATTCC AGGTACAAGT ACTCCCACTT TGATGCTACA GAGGAGTTGC TGAACTTTGT GTCATTAATC TCTCTTCGTT AGATCCCAAC CCTGTTTAAA TCCCACTATC TGCCTACTCT GGGTCTTCAC CAATTTACTA GATCATAGTT GGAGAAAATC TACAAAGCCT TGCTCCCTTT AGATTTAAAC AGGTCTCCGT TTAAATTTAG AATTGCTAAC TTCAAGCGGG CCCTTATGCG ACAGTATGCC TGTCAGTCAT ACTACATTTC CTCAATTCCA ^• TTCATGTGAC TGCTCCATAC CCTTCCCTCT CTCTTCATAC TACTATTATC TCTTCCCCCC TCCCTCATTT TTAACTGATG ATCTTGTTTC CTATTTCTCT GAGAAAATAG

AAGCCATCAA AAGAGAGTTT CCACAAACTC CTACTGCCTT ATCTAGCCCT GTACCATATA CTTTGCATTT CCTCTCATTA CCATGGATGT ACTGCCTATC TGTGCTTCTA TCTAAGGCTA ACCCTTCCAC TTCAGTTTTG AATATTATCA GCTCTTACCA ACTCAAGGCC ATTGCTCTAG CAATTCTCTC ATTCTCTCTC ATTTTCTTCC ATCAAGTTTT CCTTTTCTTC AATTAACAGA GTAGCTCCTA AAGGGAAAAA AAAGTCTTCT TTTTCAATGC TCATCATCAC TGGCCATCAG AGAAATGCAA ATCAAAACCA CAATGAGATA TCATCTCACA CCAGTTAGAA TGGCAATCAT TAAAAAGTCA GGAAACAACA GGTGCTGGAG AGGATGTGGA GAAATAGGAA CACTTTTACA CTGTTGGTGG GACTGTAAAC TAGTTCAACC ATTGTGGAAG ACAGTGTGGC GATTCCTCAG GGATCTAGAA TTAGAAATAC CATTTGACCC AGCCATCCCA TTACTGGGTA TATACCCAAA GGATTATAAA

CAATGCTGCT ATAAAGACAC ATGCACACGT ATGTTTATTG TGGCACTACT CACAATAGCA AAGACTTGGA ACCAACCCAA ACGTCCAACA ATGATAGACT GGATTAAGAA AATGTGGCAC ATATACACCA TGGAATACTA TGCAGCCATA AAAAATGATG AGTTCATGTC CTTTGTAGGG ACATGGAGGA AGCTGGAAAC CATCACTCTC AGCAAACTAT CACAAGGACA AAAAACCAAA CACTGCATGT TCTCACTCAT AGGTGGGAAT TGAACAATGA GAACACTTGG ACACAGGAAG GGGAACATCA CCCACTGGGG CCTGTTGTGG GATGAGGGGA GTGGGGAGGG ATAGCATTAG GAGATATACC TAATGTTAAA TGATGAGTTA ATGGGTGCAG CACACCAACA TAGCACATGT ATACATATGT AACAAACCTG CACGTTGTGC ACATGTACCC TAAAACTTAA AGTATAATAA AAAAATATAT ATATATATAT AAAACAACTA AAAATAAATC TTCTTTTTCT GCAGGATCAG TCCATCACCA

CACACACAGG CTGTGTTTTA TGTTGTTCCC CAGCTTAAGA GATCGTTCTC CAGATCCCAC TGCTCCTTCC AGTTGTCACC TCAGTTCTCC ACTTCTTTTT GCTGATAAAC TACTCTAACT AGTTACATAT GATTTCTGTC CCCAGGTCCC CTCCCTCAGT TGTTTTGAAC ATAATCATTT ATATCATTTA TCATTTTCAC TCTAATTGCA CAACCAAAAA CTCCCTTTTT TTTTAGATGG AGTCTCACTC TGTCACCTAG GCTGGAGTGC AGTGGCATGA TCTCGGCTCA CTCCAACCTC CGCCTCACGG GTTCAAGTGA TCCCCCTGCC TTAGCCTCCT GAATAGCTGG GATTATACAC ATGCACCACC ACACCTGGCT AATTGCTTTG TTTTTGTTTG TGTGTGTGTG TGTTTTTTTT TTTTTTTGGA CAGAGTCTCA CTCTGTTGCC CAGGCTAGAC TGCAGTGGCA TGATCTCAGC TCACTGCAAC CTCCACCTCC TGGGTTCAAG CGATTCTCCT GCCTCAGCCT CCCGAGTAGC TGGGACTACA

GGCATGCACC ACCATGCCAG GCTAATTTTT TTGTATTTTC AGTAGAGACC AGGTTTCACC ATGTTGGTCA GGCTGGTCTT GAACTCCTGA CCTCAAATGA TCTGCGCACC TGGACCTCCC AAAGTGCTGG GATTACAGAC TTGAGCTACT GCGCCGGGCT ATTTTGTGTT TTTAGTAAAG ACGGGGTTTC ACCATGTTGT CCAGGCTGGT CTCAAACTCC TGACCTCAAG TGATCCGCTC GCCTCAGGCC CTCAAAGTGC TGGGATTACA GGAGTGAGCC ACCATGCCTG GCCATAAAAC TGCCCTTTGT TAATATGACT GTTGGCCTGC ACATTGTCAA ATCCAGTGGC ATTCATCTTA CTCGGCCAAO CTACGGCATT TGACACTGTC TGTCTTTCCT TCTGTTCCTC TATCTGTTTC CAGTATACTG GCCTGGCTTT CTTTTTACCT CTTTTATATG CTCTTCCAGT CTCAGGCTCC TTTGGGGATT TGAAGGTATG TTGCATTTTG CTATTCAATG AATAATGACA AGTAATGATC ACTTAAGACA

TTAAGTGGTC AGTTCCTTTA CTAGGATAAA AATAATTTTC TTCCCAACAT GGGGCATATT CCATTTCCAG TCTGACTGTT CTGTGTAATC TTTGTATTCC TTGGCAGCCC CTTTTATATC AGTTCATCTA CTGTGCAGGA AATTGGACAA ACATTTGCAC TGGTATAACC AAATACAGTT GAACTTTTGG CTTGACTCTT AGCTGAACTC ACCAAAAATA ATTTCTGTAA GAGACTGAGA CGTCTACGAG TAGGTTTTTC AGAATTAGTA AACATAAATC AAGGATACAC AGGTAGATTT GAATTTCAGA TAAACAACAA ATACTTTTTT AGTATGTCTA CTGAAATATT TGTATCTTAT CTGGCAATTC TACCTGGTAC AGAACTAATC CATTCTCTTG AAAGATCTTG ACTCTGTAAT AAGTTCTTTG GTGATGGAAG GGAGGTATTT CTGTAATTAG AGTCACTGTC TTCCTCCCAG TTTTTTATCC TGGCCCAGAT CTGCAATGAA CACACGACAG AATCCAGGGG GGATGAAGAT GGGTGCTTTG

CAGGAAAAAA AAATTAAAAA CATCTGAAAA AGCTTTTGTA CTAAAAGAAT GTGATCTAAA AAAGAAAGCA GGAGAACTTT CTGTCTGCAC TTTACATCAG AACAACCTTG GCGTCTAGAA GCTGTGCCCT GTGGGAAGTG GTGGTGCTTG GTAAGAGATG CCAGGACCAG TGGTACCCAC TGGGAGCACT GCCAATACCC AGCAAGGAGC ATGGGTGCAG AGTAAGGCAT TGCACTGTGA TTCAGCATAA AATAACAATA AGGGAACGTC ACGGAGAAAA GGCCAGACTT CCTTTGTTTA GAATGTGGGA AATGTCTTCT GAAAAATGGT AGTAAAAAAG CATGCTTGGA TGGTCCACTC CAGGCAAAAC TGACTAATCG GGGGTCAGGG ATACAACCCC TGCATCATAT GTTTGTTTCT GTTGGGCTGA CATGAGGTTC ACTGTGACCA CTGTGGTTTA ACCCCATAGT CTCCTGGAAA TACAGCCAGG TCAAGAGAGC TCCACATAAA ACATAATCAA AAAAATAAAC TCAAGTTTCC

ACTGATCAGC TTTTCACAAC TCTTATCCTT TCACTAACTT TGGAGCAAGA TTTGAGAATT GGATGGCTAT TTGAGGGCTA TTTCTGCGCT TTAGTTCAAT GTTTTGTTCT TTCTTTATTA GAGAACTATG GTTTTTTATT ATATTTACAC TTTAAGTTCT AGGGTACATG TGCACAACGT GCAGATTTGT TACACAGGTA TAAATGTGCC ATGTTGGTTT GCTGCACCCA TCAACTCGTC ATTTACATTA GGTATTTCTC CTAATGCTAT CCCTCCCCCA GTCCCCCACC CCCCGACAGG CCCTGGTGTG TGATGTTCCC CTTCCTGTGT CCAAGTGTTC TGTTTATGTG ATAGATTACG TTTATTGATT TGTGT ATGTT GAACCAGCCT TGCATCACAG TCACTTGCTT ACAAGAAACA AACACTTCAC AGATGGATCA TTATGTGTGA TAAGTGAAAT CCAAGGATTT ATGCTCAGAG GTGGGCTTAA CAGGTAGGAA GAGCAGTATT TTCCTTCAAC CATGAGTGTA TGCAGGTTTT TCTTTTCTTT

TTTGAGATGG AGTCTCACTC TTTTACCCAG GCTGGCGCGC AGTGGTGCGA TCTTGGCTCA CTGTAACCTC TGCCACCTGG GTTCAAGCAA TTCTCCTGCC TCAGCCTCCC AAGTGGCTGG GATTACAGGC ACCTGCCACT GTCTCCGGCT AATTTTTGTC TTTTTAGTAG AGATGGGGTT TCACCATCTT GGCCAGCCTT GTCTTGAACT CCTGACCTCA TGAATCATCC TTCTCAGCCT CCCAAAGTGC TGGGATTACA GGCATGAGCC ACTGCGCCCA GCCCACAGGT TTTTCAAAGA CTAAACTTAA AAAAAAAAAA AAAATTTCCC AATGAAATAT AAAACTAAAG TGCTAAACTG TGATAGACTG TTTTACAAGA ATGCCAGTTT TCACAAGTGT CTATAGAACA TGTAATTTAG ATAGGTAAGA TGAAATTTTG ATAATATTTG ATGGCAAATT TAAACAGGTA TACAACAAAA ATAAAATTCT AAGCCCCTCA ACCAACTGAA TGGACTCCTT CTCTCAGCCA AAGGAATACC AAAGTAAACC TGAAAAACTA GTTTTGGCCA GGATTGGGGG TAGGTGGGGG AAGCCCAACA TGACTCATTA TTCTCTCCTC CCTTTGGAAT TCAGGCACAA CTGAATGTCA GCATTGACAC TAAAACACAG ATCTTAAGAC TGACAAGCCA GACTCTTTGT AGCAGAGAGC CAGGCCCTGG AAGAAATCAA GTTATTTTAT CCCAAAAAAT ATTTCTTTGA TATATTTTCA AATGGCCCTG CAAAGCTGTC TCTTGTGGGG AAAATTGACA TGCTGTACAG AATTTCCTTC TCTTTCCAAG TTTTTACTGA TCCAGGAGAG ATTTAACTAA GAGGCTAGCA TGTTTTTTTT xx xxxxx TGAGGCGGAG TCTTGCTCTG TTGCCCAGGC TGGAGTGCAG TGGCGTGATC TCAGCTCACT GCAACCTTCG CCTCCCGGGT TCAAGCGATT

CTCCTGCCTC AGCTTCCCGA GTAGCTGGGA TTACAGATCC ATGCCACTAT GCCCAGCTAA TTTTTGTATT TTTTGTAGAG ACAGGGTTTC ACCATGTTGG CCAGGCTAGT ATTGAACTCC TGACCTCGTG ATCCGCCCAC CTCGGCCTCC CAAAGTGCTG GCATTACAGG CGTGAGCCAC CGTGCCCAGC ACAAGACATT TACCGTCTAT TCTCTCTGAA GCTACTATCT AGAGGCTTCA TCAACATAAT AAGACCCTTG GTCTCCACAA CTCCTTATCT TATCCTATTA GTTTCTACTG ATTCCAGGTC TTTAGATAAT AACAACTCTT TCAACCAATT GCCAATCAGA AAGTCTTTGA ATCCACCTAT GACTTAAAAG CCCCACTCCT TCAAGTTATC CCGCCTTTCT GGACTGAACC AATGTACACC TTATATGTGT TGATGGATAT CTGCCTGTAA CTTCCATTCC CCTAAAATGT ATAACATCAA GCTGTAACCC AACCACCTTG GGCACATGTT TTCAGGAACT CATGAGACTG TGTTGCAGAC

CTTGGTCACT CATATTTGGC TCACAGTAAA CTTCTTTAAA TATTGTATAG AGTTTGGCTT TTTTCATTGA CACAGGAAAA ATAAAGAATT GGAAGGTCTT TCATCAGTCA CTGAGCCAGC TTCATATCTG ACTGAGGTCA TACAGTTCAG TGATTTGTAG CTTTGCTACT TAGATTGCTA TCCATTATCT AGAAGCATCA GGATCACGTG GGACCTATTG GAAATGCAGA CTTTCCTCCT AGAACCCAGG ACCTTGGAAT ATTCTTGGCA CATAGTAGGT GCTCAATACA TATTGAACTC CTAGGTGCAA TTCATTAATT CATGAATTAA TGAATTAACA CGCTCTCAAA GTTTAGTGCT TTTTCACAGA CTAGTCTTTC TGCCTCTTAA GCACTCAGCT CACCACGCTT CCAGTCTCAC TCCCCTATTA GTCTGATTAA AATCTGCTTA CATGTGAGTC TGAGATCAAG TGTTATCTCT TCTGAGAAGT CTTCCCTCAC TGGCCCAAAG GAATTTCTCC TCTATTTTAG CACTGTCCCA GTTGACTTGT

CATTATTCTA GTCTTTTTCA TATTAGTTGT TTTTCATATA TATGTTATTA AGGAAACTAG TCATTTCCCC TAATAGAACA AAATTGCTGG CCTTTGGGGT TGGCAATGGA GGGGAGGCTC TTCTTGAAAA GGGGGAAGAG TGTTCTCCTA ATATTTTTCT TACGAGATTT ATGTTGCTCA TCTTTAGCCT TTAGTCCCCC ATTGCCTGCC TACAGTTGGC AGAGACCATC TGTTCTCTCA CTGTCAGGAA CTGTCTCAAT TCTTGAAGTT CAGAGTCAAA AAAGAAGCAA GTTTTCCTAG CTCTTTGATC AACTTTCAAA GTTTTACTTC CATTTGAAAA TTTACTAAGT CACCAGGAGA TGGTTTATAC TGAGAAATAT CCACTCATAC TCTTCCTCTT CAACTTTCTT CCATATACAC CCTATTACAG GGATATAGTC TTACTCTATA GCTCAAAAGG ATGACCCTAT CAGAAACCTG CACAGTATGT AAAACATTCT CACCAGAGGT TCACTTGTGT ATTTCCACCC TAGAATGGAA GCTCTACAAA

AGCACAGAAT GTATCATTTT AACTTTAGAT TCTATTTTCA CACCCAGTGC TTGACACATG ATTTGAAGTT AATATTTATT TATCAAGTGA TTGTTTTAAA ATCATGACTC ACTCAACAAA GTTATAAGAA TAAGAATAGT GTTACAGAAT TGGTATACAC AAGCTGACCA TAATCAACAC ACCTATTATC ATTTTTTTGC GACAGGTTCT CGCTGTCTCA CCCTGGCTGG AGTGGAGTGG CATGACCACG GTTCACTGCA GGTTTGAACT TCCAGGCTCA AGCAATCCTC CCACCTCAGC CTCCCACATA GCTGAGCCCA CAGGTGTGTG CCACCATGTC CAGCTAACTT TTTAATTCTT TGTAGAGACA GGGTCACCCT ATGTTGCCCA AGCTGGTCTT GAACTCCTTG GCTAGAGAGA TCCTCCCTCC AAGGTCCCCC AAAATGCTGG GATCTCAGGC AAGAGCCACC ATGCCTGGCC ATAATCAATA CACTTTTAAG AATGCTAGAA TGTTATATCA GATGCATACT TCAGCACTAT CTCAAGCAAA

CTGGGGTGTG GGTTATTCTA CATATAAAGT TCAGCAGTGT TGTTCCACAG TCCCAAACTC CAACTGAGGT CAAATGTAGG GTGCAGCAAG GTCACTGGGG CTGTCATCAA GGGCCTCTCC TTGCACTCTT GCCAACCCTG TTTCTTGATT GTCTCTACCA CCATGAGTCA CCAGCAATCT CCCACAGTCA CTTGTTTAAA AGTTGACAAG TATTGTGTGA ATTGCAGGCA ACCCCTTGAC TCCCTGATTG CCTGGTCTTC TTCCTTGGGC TCTACCATTT TTTTTCCCCA GCACTCTTTC TGCTGCTCTA AATTTTAATT CATGCAATTC CATATGTGTT TCTCTATCAT TCTTCATCTC TTTCCTCTCC CTTCCATCCA ATTTTGTTTG TCTGTTTGCT TGCTTGCTTG CTTTAATACA TTTCTCTTTT TCTGAGAAGG CTTGAGTCCA AAACTCTCAG TTACCTGTTG TTCTGTTTCC CGTTAGTTAA TCTCCGAACC TTCATAAATT AAATCTGACA AAGTCCCCTG ACTAACAAAG GAAATGCACA

AGTCACAGTA AAAGGGGCAC ACACAGAACA CAAATAGACC CAGGGTCTTT TCTGTTCATC ACTCAGCTTT TTATAGGAGA TCCAGGAGAA ATGAAGTGGA AAGGGAAGTG TGTTGAGTTA CTATACAACA CAAGAGTAAA CTTTCTTATA AGTGGTAATT TTTTTTTACA GGAATAATTG AAAATGGAAA TTACCTTCTC TACTCATAGT AAGTACTCAG TGCGTTCTTG ATGGGATGAG AATGTGTTTG AGCTTTAGTG TAAGGCAGAA TTCTGTTTAG TCTGCCAGTA TTGGAGAAAA ATAAAACACA AAGGGACTGA CATGTAGGAA GTGGCACCTG GGAGGGTCTC AATTCTTCCT ATTACAAAAA TGCCCCAGAG AAATAAAAAG CTTGTGTACA TGTTGAGATG GGAGAGTTCT CTGGCCCCCC TCGCAGGATG TGTGACAGTG GGGTGGCTCT CTGCTGCGCC ACCATGAGCT CAAACCCCTC ATAGGAGGGG GAGCACACAG GCAGGAAGGT GCAGGAGCTG GGCGAGCTCT

TTGGGCTCTG GCCCCGTGGT ACTGTCTAGA GGTGGGTGCC TGCAACTCCT GAAAGCCCAA GTGGGCATGT GTTACAGTGC ACTCTTTCAG CTTTGCTGTC TGCAGCTTAA GCGTTAACCA GCTCAGTTTC TTCTTGGTAC CCAGGTCCTT GTCTGGCATC CAGGAAGAAT CAGGTTACAC ATGGACTTGA AGGATGAATG TGGGAGTTTT ATGGAGTGGT GGAGGTGGCT CTCAGTGGGA TGGATGGGGA GCTGGAAGGG GGATGGAGTG GGAAGATGAT ATTCTCCTGG AGTTTGGCTG TCCAGCAGCC GATCTCCTCT CCAGTCGTCC CCAGCCTCTC GACGTTCAGA TGCTCCTCTT CTCTCCTTCT CTGCCATGCT GTTCTGCCGT TCATCTGCCT GTCTCTCTCT GGAGCCTGGA ATTTGGGGTT TATATGGTAC ACAATAAGGG GCATGGCAGG CCAAAAGGGA ACTTTTTAGG TGCAAAAAAC AGGAATGCCT CTTCTCACTT AGGGCTATAG ATTTTCAGGC TTGAAGGTGG GGCCTTTACC

AGCGAACCTG TATTTCCCTG TCTCCTGTGC ATATCAATGT AATCAAATAC TGGGCTGATC CAGGATGTTT CTTTAGACCA ATTATGGGTA AAATAATTTA CATTCAGGTT TTTATATTTG CTTTTGTCAT TTCTTTTTAA GCAATCATGT AAAATATCTA TACGACAGTA ATAGATGATA GCGAACCTAA TTAAAATTAC CAGAAACTTA AGAATCTCTA ATGATTTCAA CTGTAACTAA GGTTATTTCT CTTTATGTTG AACAATGTTG GGAGATAAGA CACAAGAGTT TCTGAAGTAT TTCAGAAACA CAAAGAGGGA GGTTATATAA ATAATATTTT TTTCCTACTT TGGGAAAATG AAAGCTAGTC ACAAAGTTAA ACGAGTGGTT ATTTTAATAT TTAAAATACA GGCTTGGATG TATTTCCTGT TAAAGAAAAT AAAATGCAGA ATATTCAAAA CGTCTGACCA CCCTTCTAAG AAAATGCATC TCTGAGGTAT TTTTCCTTAG AAGTTATTGT AAAAATCCTG GAGAAGCTTG AACACAGCAA

AGCAAACAGG ATGCAGAGTT TAATCTGTGG AAAGCTTAGG GAAGAAAAGC AAATCATTAA AAATAGGTCT TCCTCTGAAG ATTTTTAAAA CGCAAAGAGG GTGGAATAGC AATGATAATA AAAAAGCTGG CATAGAGAGT GGCACAATTT GCTGTGCCAC TGAGCTGACT GGATGTGTTC TGAATTTCTA GGCATTAGTG TACCTTTCCA CACGCATTCT CCCTTTAAAA AAAATGCCCA CACACTGAAT ACTTTTTTCA TGCAATTTAA AATAAGCGCA CCATCTAGTT TACAGAAATT CACTAGAAGT TATTTATCCT AAAATAGCAG AGATCTAGAA GAATTTTGAG CTCTAGGACA TTTTAGACAC ACAGAAAGAA GAATCTGGAC AAGTCTTGAC CAGACATGAC AGAATAGAAA TTTCTTTTCC TATTTATCTC TTTGAATAAA ATTTTCAGGA TCTTACAGTG GACAAGTTTG TTATCTACAC ATTGTGAAGC ACATTGATTT CTCCTCTGTA GCCTTAGGAA GATCTGAGAG GTGACTGAGC

TGATTGAATG ATCCGTGACC GCTCTACTGG GACCAGTAGT AGAACTTTAC TGGTGGAGAC CTGCTGGAGG TTTGAGAGCA GACTTTGAAA ATTACTAGAG CTACACAGAT ACTGTGTGGC TAACTGGATT ATGTTTAGAG GCTTTCAGAA CTATGCTGCT GCTGCTGCAG TGTAGCCAGG ACGCACAGAG AACATCTAAG GCTCTTGAAT GGGGCGATAG GGACAGATTT CAGCAGCCAT CTGACTTCAG TGCTCATTTT GATGCTTTCC CTGCAGGGTG CAGTGTGCAG TGTGCAGTGT GCAGTGGTGG GAGGCTCACA CAGGAATACT TGCTTCTGTA GCCCTAATTT CCGGTTCAAA CTCTGCATTC ACCTTGACAG ATTCTTTCCT TGGCCAAAAT TTAGTTAGGC TTCTGGGCTT TCTCTTATGC CCACCTGCAG ACTTTTTGGT AAAATCCAGT TTTAGTAAAG AGCTCTGCTA AGTCAGTTTA GCAAGAATCC CCACCTCAAA AGTCACTATC TCCCTCCCTG GTAGTGTCTG GCTTGTCTTC

AGCGAGAATT CTATTAGGTT CTGTTAGATT AGAATCCTCC TTACCCTTGA TGCTTCCTCT TAGTATTTTT TCATCCACTG ACTCCTTGAC CCACCTTGCT CCTCGGCTAT AAATTCCCAC TTGCCCATAC TCTGCAGTTA AGACTATTTT CTCCCCACTA CTGCAAAATC CCATTGCCAT GGTCCCTATA CTATCTCAAT GGTAATGAAT AAAGTCTGCC TTACCATGCT TTAACAAGTA ACATTGAACC ATTTTTTTCT TTAACAATCT GCTGCACAAT GAGATTACTA AAACTTTATT CCATTTTGCC ATGCTGGATG TCCTCAATGG AATGGCTCTT GTGAGCACCA AATCATTGTG AGAAGGAAAA CCCATCTCTT ACAGCCCCCT GTAACGTGAT GTATGTTACA TGTGATGTAT GTTACATAGT TTTTTTTCAT GTTGATCACT TTTTGCCCAT TTTCCTATAT CTTATCAGTT GGAAGACTGT GGAAGTTTGT AGTACTAAGC CACAAGATGA CTAAGAAGAG TTGAAAGGGC AAGTGGGGCT

AAAAACAGAT TTTGTTTGAC TTACCCCACC ATTCCCCCTA TCATGGGGCT GAATCTGCCT GGAGGAAGGA GCATCTTTAT CTTTGTACTG TGAACCACAC AGTCTAGCAG CAGCACAGCC AAGGCACTTG GGGTTTCATG AGACTAAGTA CATGCAATTC TATTGTAAAG GCTTAAAATA TATACAACTG ACCCTTGAAC AACATGAATT TGAATTGCAT GGTCAGTTAT ACGCAGATTT TCTTCCACCT CTGCCACCCC TGAGACAGTA AGATCAATCA ATCCTCTTCC TCCTACTCCT CAGTCTACTC AAAGATACTT GAAGTCTACT TGAAGATGAC AAGCACAAAG ACATTTATGA TGATCCACTT CCACTTAGTG AATAGTAAAT ATGTTTTCTC TTCCTCCTAA TTTTTTAACA CTTTCTTCTC TCTAGCTTAA TTTATTGTTA AGAATACAAT CTATAATACA TATGACATAC AAAATATGTC TTAGTTGACT GTTTATGTTA TCTGTAAGGC TTCAGGTCAA GAGTATGCTA TTAGTGGTTA

AGTTTTCGAG GAGTCAAAAG GTGTATGTGG ACTTTCAACT GCAGGGGGGT GGGCACCCCT GCCCCCATGT TGTTCAAGGG TCAACTTTAC TGCCAAAGGC AAGCCTTTAC ATCCACTTTT TCCATCCCAT CAGTAAATGG AAAAAGATAG CTACAGTATC CCTGCGTCAA ATCTTTTTTT TTGCAGATCA CAAATTGGCC ACTCACCTTG CTCTGTGAGG GGTAAAATGC CCCACTTTCT TTAGTAATAT TTAAGTTAGA TAATATTTAA GTTATAAAGT TGTTCTTTGT AATCGTTAAT TGTAATTTTT ACATAGTTTC TTTCAAACAG AAATAGCATT TTTGTTAGAT AACCTCCCGT ATAGATGATG AAACTCCTTT TAAGGGCTAT CTGAATTTTA ATTCCTTGAA AAGGCAGAAA TTGGATAGCT AGTAGTCATA AATGTACTGT GGCTTCCCCC AACCATCTGG GCTATATAGA AGCTGCATCC TTGGACTGCA GTAGAGGAGT CTTACAAAGC ACAGAGCAAC TTCTCTCCTG GGTTGCGCTA

GTTATGATGG CAATTTTAAA TGTGTACTTT TACCCAAAGA AAATCCTTAT TATCAACAAT CACAATGCCA TCATAACCAT GGTATAAAAA ATTCAAAATG TCCCAGCTGA AGTGGAGGCA AAGACTCAAG TTCATGGAGT CAGAGTTTCC TTGCTATTCC TCTTTTTCAA ATGACCATTT AGTAAGCACC TGAAGAAAAT ACTATGGACG GCATTGAAAA GTGAAGATAG GTTTAATCTT CTCGAAAATC TAATTCTCCA GATGAAACGC TGACACTTAT CCACCCCACA GACCCTATAG CAGATGTGTC ACTGGCCATC ACATTTGACA CAGAGAAGTC ATAACTCAGT CAGCACAGAG ACATTTCCAT GAGTTTCTGA ACCATGGACA GAACGTCGTC TGTGGGACAT GAAAACTGGA ACTTAGAGGA CAGGCACATC TGAGAAATGG GCAGTTTAAA GGCAGAACAT AGCACATATG TGACTGGGTT TTAGAAGCAA ATTTACAAGA CGCACTCTTC TTCATCCTAA ATAATCTGCA ACCAAAGCTT

CCAAAAAAGA CAATTTAGGA ATGCAGAGGT GAGGAGTAGG GAGGGGAATG GGATGAGAGA GAGTGGAGAT TAATGGTGGG CAGAGCGAGG TTTAGAACTT AGTGGTTTCT TCAGGTTCTG AACTGAAATT TGTATACTGT AAAGGCACAA ACACCATTTT TAACAAAAGT GAGCAGGACT TCCTATCTGG TTCAGAAAAT AGGTGAATAA ATAGTACGAA TTATTAAAAA TAATAATTTC CACTTATACA TAGGAAACTT GATAGGAACC ATGATAAATG CTTAACTCTT AATCTTCAAG GAACTCTGCT AGGGATATAA TATTATAAAT CTTGTTTTGC AGATGGAGAA ATTGAATTTT AACCCAAGTT ATCATAACCC TTAAATGATT AAATGATACT GTTACATGAG AAAGCTGCGT ATCTGTTTCC TGGATTTGTA GCCATAATTT GTGTCTCAAG TCCCTTTTGC TGCCAGCTAT CTTGGGTAGG TGTGTTCCCT TTGGGCTGTT TGATACCCCC ACATTTATCT TTTTTTTTTC

TCTTTTTTTG TTGAGAGAGT CTTTCCCTGT TGCCTAGGCT GGAGGGCAAT GGCGCGATCT CGGCTCACTG CAACCTCCGC CTCCTGGGTT CAAGTGCTTC TCACGATTCT CTTGTCCCAG CCTCTCTAAT AGCTCGGATT ACTGGCATGC ACCACCACGC CCACCTAATT TTGTATTTTT AGTAGACAAG GGGTTTCTCC ATGTTOGTCA GGGTGGTCTC AAACTCCTGA CCTCAGGTGA TCTGCCTGCC TTGGCCTCCC AAAGTGCTGG GATTACAGGT GTGAGCCACC ATGCCTGGCC CCAAATTTAT CTTTAATGCC CCAAATTATC TAGTTCCCAT GACTGGGCTT CTGCTTTGAT CCTTTCTGCA CTTGCTGGAC CCTCTCCCTG GGAAATGAGA TTGTGTCCTG AGCCCCTAGT TAGAGGCTAT GTCTCTGCTG TTCCTGAATG GGCCTCCTGG ATGAGACCTC ATTAAAAGTC TAATTCTCTT GGAGAATTGA GAGATACCTA TTTGTCTCAA AATCATTGAA ACCAATTAAT GTATTATGAG

CCTCTATCCA GTGATTTGTA CCTCAATTCC CCAATCCAGC TGTCAAGGCC AATTTGTTCT ACCTTACCTA GTAGGTAAGT CTGGAATTGT AGCTGTGGCA TTTTCAGTAA TGGTACTCTA GGTTAGCAGT CCCCAACCTT TTTGGCACCA GGGACCAGTT TTGTGGAAGA CAATTTTTCC ATGAAGGGCT GGGCAGGGGA GTGGTTTCAG GATGAAACTG TTCCACCTCA GATCATCAGG CATTAGATTC TCACAAGGAG TGCGCAAGCT AGATCCCTCA CACATGCAGT TCACAATAGG GTGTGCACTC CCATGAGAAT CTAACACCGC TGCTGATCTG ACAGGAGACA GAGCTCAGGC AGTAATACTC ATTTGCCTAC CGCTCACCTC CTGCCGTGCA GCTCAGTTCC TAACAGGCCA CGGACCAGTA CTGGTCCACG GCGCAGGCAT CAGGGACCCC TGTTGCTAGG TATAAGCATC TGGCTGCTGC ATGTCTTCTG TGTAGCTACA TCTGTATGTG TATCTGATGA GATATAAATT ATTTGATTAT

AAATTACTTT CTTCATATTA GAGTTGTGAA TGAGTATCAC ATATAATTAT ACATAAACTA GGAATATGCT TTTTAATAAT GTATATAAGT AAGTTTCCTT AACTATGACT TTCATCTTAG CGTAGTAAGA GGGTGCTAAG AAATATTTGT GATGAAAATA GGCATTGGTA GAGTTGAGAC CACTGGGTGA TGAAAGAGTG TAAAGATTTT AAAGCCTTCA GATGCTGGTT CAAGGTGAGA AATGTGATTG GGAGCAAATC AATTAACTTC TTGAAGTCTT ATAGGGCAGT TATGAATACT TAATGTTAAC ATATGTAAAG CTCTTCTGCC CTGTATACAG TAAATGCTAG TTAGCTATTA TGATCACTAC TAAAATGGGG ATGACATAAA CCTCATAAGG TTTTAAGTAT TATGCAAGAT ACTATACAAA GTCCAGTAAA TATCACATTC AATTGAATCC ATGATGTCCG ATTATTTTAG CTACTTCCAA GAGAGAAAAA AATGCTGTCA GTTTTACTGT TCTTATAGAG AGCAAGGCAG ATCCCAATTC

CCAATGTGGT AACGTGAAAA TTTTTGCATT TGAATCAACA AAACACTTTC TCCTTTCTTT CCTACTATTT AACAACTGGT AAGTCTATAC TCCCCCAAAT CTGGAATTCT CCTTTCTTAT TCTTTTTCCT CCTACCAAGA CCGCAGGATC TTTTACTTGG CTATAAGGGG TAAACCTCAA GTAGTACAAG TTCTCTGTAT TACTTTTATA CTCTGTCACA GATTCCCTTT GTTTCCTCAT CTCCATGTGA ATTTAGTTAA ATTCTCAGCA TTCTGATCCT TACTATACAA GGTAAATGAA TATAAAAACA AAACGAAACA AAAACCTCTT CCTATTTACA TAAGGCCCCA ACCTAATATT TAGTGATATA TATTAATGTG AACAAGGAAC TAACGAAGAC TGGGAAGAAA TTCACAGACT TGAGAGAAGA AATGGCAGGA TTTCCTGGGA ACAATTTCAT GTAACGTCAA AGGTGGTAAA AGGTCAAATA GAATGAAGAT GGAGAATACC GGATTTTCTT ACAAAATGAT TTCCCAGGAG ATCTCATCAA ATGCACGAGG ATACCTTCTC AGTTTCACCT AGTGAGTAAA AGACTGGTAA CATAGCTCAC TTACAATTTG GATAAACAAA ACTAAACAAA CAACATCAAA ATTTCAGAAA AAATAATAGC AAAACAGAAA TCAAACACTC AAATTTTTGG TCCTTCTGTT TATTTCATTT TGGATACTCA GTGAATGTTA ATTAACCAGG AAACTTAAAA GTTATTTCAA TTATGAACCT CTTCAATCCT TCATCAATTA TTTTGAGTAT TCTGGTCTTA AAAACATCTC TTTCTTCTAC AAACTTCTGA AAGAGATGAA CACCTCCACC TACACCAAAA TAATGTGCTT TGCTGGCCAA AAGTACACGT CCATTTTTAC TTAACAGTCT AAGGAAAGTC TGGTGCAAAT TACTATAATA ATCTGGGTTG TAAATGGTTT CTGAGGTGAG

AATGAGATCA TATTTTACAA AAAGTTTTTC ACTACTTAGT ACAAGCTTAC AAAACTCAGA CCACTCACCA GAAAAAAATC GGCATTTATA TAGTTGTGTT ACTTTTGGTT TCCTGCATCT TTTCACATCT GGCTCATTTA CATCATTTTC TTCATCTTCC AAAGTGGAGT TAGCTACTAC ATTAGGTAAG GTTACTTCAT CAATCACCAT ACTGTTATAA TCTTGAAAGT GAATTTCTTT GGACCCTCCC TTGAATGCAG TTATACCTAG TAAACCTGAT CCACAACCAA GATCCAAGAC TTTTTTCCCA GCAAATTTCA CTTTGGCCTT TGTGAAATAA GCCAGGAGGT CAAAGGTACA TTCCCAGATT TTTAAGCCTC CCTCATAAAC ACCTGTAATC AGATCAGAGT GAGAAGAAAA GCTTTTTGAA ACTATGTTTT CTCCAGGGAA GTTCTCTTTC AACAAGATGG TTTTCACTAC TGATAACTTA ACATGCTGGA AACCTGGTAA TGTTTCTATG ACTTTATTTT CTAACATCTT CTTTAAATCT

TTAGGCATAG CATGCTCTTT GGCAGCTCTC AAGGAGGGCT GTTTTCCATG TGGCTCCAAG TTCCTTGAAC TGCTGGCTGC ACTGAGTGGA CTGTCTGTGT CTTGAGAGGG AGCTGCATTT TCCATTGACT TATGTTCCCA CAAGTGATCC TGAGGCAAGT CAAATTGTTC TGCAGAACAT TTTCTGTCCC TCTCTTCTCC TTTTTGACTT TCTGAGACTG ACAGCTCTTT TGAGGAATCC AGGGTCAAAG CTCCATCTCT AATGGGTGTT AATTCATTTT CCAGATGGTC TTCTATAGTG AAATTAAACT GAAAGGTCAT CCTCTTATTA AATGCACACA ATCTTTAAAT TCAGATTCTT CAACTTCTGG ATAGAATTTG ATGATACACA CAAATCTGCC TCAATTATTC AATTAGTTTT GTTGGGCCCA ATTTCTCTTT AGCAGCTTAT ACATGGTAAC AAATATTTAG AGATATTTCC AAATGACTTT TTAGACGTCT TTGGTCCTCT TTCCAAGCAG CTCTGGAAAG AAAAAAAAAA AAAAAAGAAA

GAAAATGATG ATTAAAGCAA AATGGCACAT TTCACTAAAG TGTAATATTA AACAGCCACC CCCACCCCTC CCTGTCCCAC CATACAGCTG CTTTTTCTTA AAAAGTTGTG GGGAAGAGAG AGAGATAAGA GATTTGGACA CTCATACACA CCTTAAGGGT TCCAAAGTGG GAGAAGAAAA TCAACTATAA AAACAAACAG AAGAACAACA GCAACCACCA CCACTACCAC CTGGACAAAC ATAAAGTCCA AGATATTCAG ACAGGACAGC CTAGCTACTT GCTGTCTTTC AGCTGTCTTG ATTTGTGTCC AACCATATTC ACCCCCTAAG CTTCCAGAAT AACTTCACTT CTGTCTTTTA CAGAAGAGGT GCAGTATTTT ATTTTGGTAA GTCAGCGTCC CTTTAAAAAC ATGCATAGGT ATGGCCTGGT GTGTGTAAAT TCATCCAAGA CTTCACTCCA AACATTTAGT CGAGAACAGC AGCCCTAAGT GTATAGAAGT GGGGGTAATT TGGCAATAAT TAGTAAAGAC TAATTCGGTG

GCAGAGCAAA CGCAAACTAG GGCAGTGCAG TAGTTTGGAG AGACCTGTAG AAATAAGAAG CAACTTTATT GAGAATCTTC TATCTACTGC GCTAGACACT ATACCATCTG CCTCAATTTT CACAGTTCTG GCAAGTGGGA TCTTTGTTCC CTTTATACAA GATTTACAAT TTGGGGGAGA GGCGGGTCAC CCAGTCCCGC GGCTAGGAAC GCGCCTCTTT CCTCTCCCAT CACGCTGCAA GGCTTGGAGT CACTTCCGGC TGCAGGTCCC GGAACAAATC CGACCCCAGA AGTGGGGACT TCTGGCCCTC ACCTCCCCAT TTGAATGTAA TGTTTACAGT GATCCAGACC TGGGGATGCT TGCTTCCCGA CGTGTCCTGG GATCGCGCTT CTGAAAAAGC TCACCTCACA ACGCCTCCTC CGGACCTAAA TCGCGCACCA GTGAGTCGAG TCCTCCAGGG GCTAGAGAAG CCCGACTTTC TTTCCGGCCT TGAGGGACCC GGGCTCACCA AGAAACCAGC CGCCCTCCTC TCTATGGTTT TGGAGCCGGC

GGAGAGCGCG CAAGGGTTGG CGGGACTGCG AGTTTCCGGT CTGGGCTTTG GCGGGTCTGG TTTGAAGCTC TCCTGTTTGA CGAAAGTATG TCTCAGGAAG GTGCGGTCCC AGCTAGCGCG GTTCCCCTGG AAGAATTAAG TAGCTGGCCA GAGGAGCTAT GCCGCCGGGA ACTGCCGTCC GTCCTGCCCC GACTCCTCAT ATCCTTCCTT GGTTGTCACT TCTACCTAGA GAAGGGTGTG GGCGGGTCGC GAACCTTTCT CTTCTGTCCC TTCAGACCCA CCGCCAGGCT GGGTTATATT ACCGCGGCCT GAACCCCCTC TTTTCTTTGT CAGTGAGTGG GATGAAAAGT GAGGGACTGG AGGGGAAGCG ACAACCGTGG TAGATTTAAG TAAGGCTTTG GCCCTGGAAA GCCTCGCGGA CGTGTTCTGA CCCAAGGTTT TAGCAGTGGA TGTGGCGTTT TCTTCCATTC CTTCTTTCAG TTTTTCTGTA CTCGTTGCTT GCAATTAAGT GTAAATACTT TTGCTAGTGG ATAATGGGGG

AGGCAAGGAC TGAGACCTGC GGTATGACGA TAGCTCTGGC TCTTAATAGT TTGAGGTAAA GCGAGATACT CTGAGCTTTT GTCTCCCGTA AAAAGGGTGG TGAATATGAA TAAGGGCTTT CTTAGCGTTA TAAGAATTAA AGGGCATAGT TCTGTGGTGT GAAATCTTTA AAAGATGTTC AGTAAATAAA AATGATTTTC CTCCTTCCCC TCTCAGACCT CTTTTTCTTC TTTCTTTCTT TTTTTTTGAG AAGTTCTCAC TCCTCTCACC CAGGCTGGAG TCTTTCTGAA AGAGTTCTTC CGCTTGTTGT TGGCTTTCAA CTGTTGGATT TGAGGCGCTT AGCGCCTTCT TCGTCCGGGT GCAGCACATT CTTGATTGGT CTCATGCCTT TGTGGTTGTA AATGTGCCTG GAATCCTAGC CTTTCATGGT AAACCATATG TATATGTATC TTTTTCACAA CATTTGAGCC CAGCTTTATA CAATTACACT CAAAAGAAAA AAAGTAACCT TCACTTGAGA GAATCTCAAT ACTGCACAAA TATTGTGCAG

CTAAAGCCCT ATGTAATCAC ATAGAAGTCA TTCACCTAGG CATTAGCAAA ATCTCAGAAG GTGCCAAAGC CCCCTTTTTT AGTTTTTGTG TAGGTACAGA ACTGCCGTCT TCAAGGAGTT TCAACTTGAA AACAAATAGC CACCCTCAAA ACATTCAAAA ACACTTAAAC TGCGTGCATA ATGTGTGTGA GACATGGTGT TAGGCTTTGG GAGAACAGAG ACACGGAACG TGATTCCTCT TCTTCCCCAC AAGCTTATAG AGAGACTTCA TTAAGTTGAA AGTCAACATT CCCACCTAGC TTTGCACTTC AAACGACATA TTCAAAAAAG CCCAAACTTC CTCTAGTTTT CTTCATCTGA GTAAATGGTT TCACAAACTG AAACCTTGAA TCCTCTCTGT CTCACACACC CGATCAGTAA GTTCTATTGT TTCTGATTCC AAACTATGTC TTGAATCAAT CCGTTTATCT CCATCCTCAT TGCTACCACT CTGATTCCAA ACCCTTATCA CCTCTCACTT GGAGTATTAA TAGTTTCCTT GTTTCTACTC

ATAATTCATT ATTCCAAAAA AGTTAAGAGG GGAAAAACAT AGATCTCGTC ATTTCCCTTT TTAAACCACT TTACCTTCAA GGTTCCAGGT GATCTAAGCC TTGCCCTTCT CTCATACCTA GTTAATTAAC TACACTCTGT TCATGAATAC ATTAGGCTCA CCTACCTCAA GATCTTTTTG CTGAGCCTGA TTTGTTCTCT CAGCCTTTTG CATATTTCAT GTTTATGTCT TGGCCCAAAT GTCACTTCCT TAGAGGGGCT TTTTCAGAGC CTTCAATCTT AGGCAGTTCC CCCAAACGCA GTCTTACACT TGTATCACAT TGGCCTGTTC AGTTTTCTAA AAAGCACATT ACCATTAAAA GAAATGCTCT TGTTTGCTTT GTATATTTTC CACTTCTACA CATTATGTTG CAAAGTTCAT AAAGGCAGGA TGTTGATTTT CTTCACAGCG TTACCCTCAG CACCTAGAAC AGTGCCTGAC ACATAGTAAG CATTCATTAA AGGGCTAAAA ATATTTCATG TTTTAAAAAT ACTTGGGAGT CTAATTAGAC

AATACTTTTT TTCAGCTTAA TGGTAGTATT TTAGCTTCAC TATTTTAACA AATGAAAAAT TTGCAATAAA TCTACAATGC CATTACCCCC CAAAATCTTT TTCATGTTTT GCATTTTACG TATTATTTTC CAGGCCTTAC CTGCATGTCT GCATAATCAT AACTGACTAA TTTTGGAACA GCTGGTAATT ATTTGAGCTT TACTGAAATT TTTTCATGAG GCCAATTCTA CCCTACTGAA CTCAAATTTG AGTTAATGAT GACCTCATTT TGATTGCTGC TGTAAAAAAT AAGATTTCGG AAGAGGAATG AATTCTTGTA TTACTGTGGT AGGACTATGG GTTTTTTTTT GTTTGTTTGT TTGTTTTGAG ACGGAGTCTC ACCCTGTCAC CCAGGCTGGA GTGCAGTGGT GCGATCTCAG CTCACAGCAG CCAGGTTCAA GTGATTCTCC TTCCTCAGCC TCCCGAGTAG CTGAGATTAC AGGCACGTGC CACCATGCCC GGCTAATTTT TTGTATCTTT AGTAGAGATG GTTTCACCAT GTTGGCCAGG

CTGGTCTCGA ACTCCTGACC TCGTGATCCG CCTGCCTCAG CCTCCCAAAG TGCTGGGACT ACAGGCGTGA GCCACCGTGC CCGGCCGGGT TATTCATTTT TCTTATTAAC ATTCTTTGAT GATTCTTATG GTGTTGTTAC AGTAAAACAT TTCTAACAAT TATTCTAACA ATTATTCTTG ATGGTGTATA TGAAGAATTT ATTGTCGTGT ATTTGTAAGC TGCTATGTGC AGAAGAATTT CAGTCAAATA AAGTTGGTAA GATAGGTATG TAAGTAATAT GAAAAAAGAT AGAAGGTGAT GAGTGACTTA GGTATAAATT AAGTACAATA GAAATGTTGA GGAAAGAAAA ATTTCTTGTA ATAGAAATCG GAAGTACAAA CTGGGCATGG TGGTGTGCAT CTCTAATCCC AGCTCCTTGA GAGGCTGGTA TGGGAGGATC ACTTTAGCCC AGGAGCTTGA GGCTGCAGTG AGGTGTGATC ATGTCACCGC ACTCCATCCT GGGTGACAGC AAGACCGTCT CTCTTTTTTT TTTTTTTTGA GACGGAGTCT

CGCCTATGCT GGAGTGCAAT GGCGCGATCT TGGCTCACTG CAACCTCTGC CTCCCAGTTT CAAGTGATTC TCCTGCCTCA GCCTCCTGAG CAGCTGGGAT TACAGGTGTG CGCCACCATG CCCAGCTAAT TATTTTGTAT TTTAAGTAGA GACGGGTTCT CACCATACTG GCCAGGCTGG TCTTCAACTC CTGACCTCTT GTTCGCCCAT CTAGGTCTCC CAAAGTGCTG GGATTACAGG TGTGAGCCAC CCCACTTGGC CCCGAGCGAG ACCCTCTCTC TAAAAAAAAA TAAATAAATA AATCATAAAC CTGTGGATTA TTGTAGCATT GTTTCTCATC TGTCAAAAAT ATTTCATGAC TATGCATAGT TTGAAAAGGC AAGTTTGTCC CTGGGCAATT TTCAAAATAT TTCTTTAATG TGTTTTCACA ATACTGTTTA CCTAATAAAT CTTAAGTTTT TAAAAGCAAA ATTAAGCCAG TAATTTGAGT CCAATTCCAA TCTCTTATGA GTCATTGCTT AAATTTCAAA AGGGTTTTAT TTTTTTTTTA

GGTTTGTTCT GAGTAATGAA TACCCTATTA CTATGATACT AGTATCTTCC TTAATTATCC TACTCATTGT CTCAACATTC TGACAGTTGG ATTGAGCATA TTCGTAAGTA AAATTGTTTT AACTGTATGA TGTACTTTGA TGTTAAGGTC CGAGTCCCCA CATACCTCGG TAGATGTGTT CTTACAGTTT TGTATTCCCT TGAAATGTAA CTGTTCTCTA TGTTACAGCC TTTATAACCT TCAGTTACTT GAAATGAACA AATTCATTCA AATTCCAGCA CTTAAAAGTT TTAAATTACA TTTTGGATAA ATACCAAAGT GTTTTGTTGA TGATGTATGT ATAAACAAAT TGTAAATATT AAACGTTAGT TGTTACGATT AGACCTATAT AAAACATGAT ATGCAGTCTA CTGAATAGCT ATCAGCCTCT AACATGTTTA GTGTCATTTA GAAAATGCTT TCTAAATTGC CAAAAGCTGA TTGTCTAGGT GATAACAAAT TTACCATTTG GAGGAAGTTG ACTTTCTCAT TTTCATGTCT TCATCAGTCT

TACTTGATGA GATTCATTCT TCTAGTCAGA AGAGAGTTTA GACTGCTCAG TTTACTCATA TTTTGAGTTA GCTTTTCTAT TTAGAGTTCA CTTGGTTGTG GAATATTCAT TTATAATTTG AATCTACGTT GTGTAATGGG ACCTAATTTT TTTTTCCTTT GTTTTTGTTG GAGTCTCGTT TTGTCACCCA GGTTGGAGTG CAGTGGCGTG ATCTTTGCTC ACTGCAACCT CCACCTTCCA GGTTCAGGTG ATTCTCCTGC CTCAGTCTCC CAAGTAGCTG GGATTACAGG CATGCTTCAC CACGCCTGGC TAATTTTTGT ATTTTTAGTA GAGATGGGGT TTCACCATGT TGGCCAGGCT GGTCTCAAAA CTCCTGAGCT CAAGTGATCC TGCTGCCTTG GCCTCCATAA GTGCTGGGAT TACAGGCGTG AGCCGCTGAG CCTGGCCCCA GAGTTTGTTT TGTTTTGTTT TCAAGACAAG ATCTCACTCT ATTGCCCAGG CTGGAGAGCA GTAGTGCGAT CATAGCTCAC TGCAGCCTGA ACTCCTGGGT

TCAAGCTATT CTCCTGCCTC CATCTTCTAA AGTGCTGTGA TTACAGGTCT GAGCCATGAT GCTTGGCCTG TGTTTTTGTT TGTTTGTTTT GGGGGACAGG GTCTTGCTTT GTCACCAAAA CTGGAGTGTA GTGGTGCGAA CATAGCTAGC TCACTGCAGC CTCCATCTCC CACGCTCAAG CAATCCTCTC ACCTCAGCCT TCCAAGTAGC TGAGACCGCA GGTGCGTGCT ACCATGCGTG GCTAATTTTC TATTTATATA TTTATTTTTT GGTAGACATG AGGTCTTGTC ATGTTTCCCA GGTGGTCTTT AACTCCTGGG CTCAGACAGT CCTCCCGCCT CAGCCACCCA AAGTGTTGGG ATTACAGGCG TGAGCCACCA TGCGTGGCAT AATTTTTTTT AAGTAAATTA TTTTTTTATC TTGAGTATAG AAGTGATTCA TGTTCATTGT GGAAAATATG AAACATATAG AAAAACAGAA AAGATTACAA AACATCTAAT CTGAAATGGT TAAGATTTTG ATGAGAACAG TCTCATCTCA TTTCCGTATA

TTCCTGCCAG CCTATCCATC ATTCTTCGTA CATGTTTATC TACATTAAAA TTGGTGTTAT ATTTTGGAAA CTTTTTGTTT AACTACATTG TGAACATTTT TCATGTTTTA AAATGTCATT TTAATGATGG CAGATCCTAT TCAATAGATG TACACACACC TATTTAACTG GTCCACAATT GTTGGATATG TAGGTCGTTT CCTTTCTCTC _TTχχ_TTTTχχ TTTTTGGCTA CTACTTAATA GTTTCTCTGT ATAGAATGTG GTATTTTGAA AGTGTATCAA GCTTTAGATT GGTAGTATTC TTGCATTTAA TAAAGGGCAG TGGCCTTTGT TGACTGACAT GACAATATTT TTATAAAATT TGTTATTTGC TTTACAGAAA TTTTGAAAAT TATTGTAGAA ATGTTTTTAC CTCATATGAA CCACCTGACA TTGGAACAGA CTTTCTTTTC ACAAGTGTTA CCAAAGGTAT AATACTATTA CCTGAAAATA CATGTTATAA GGAATCTAGC CTCAGTCTTA GATGATTTAT TATTAATTAT GGCTCTCTTT

TTCTAATATA TCAAATATAT TCAAAATAAA AATAAGGAGT AAGTAGATCT CATGTGAGAC TATAATGGTG TTAGTGTGAT CATTAGGCAG TTAAAAACTG TTACAGGCTG GGCACGGTGG CTCATGCCTG TAATCCCAGC TCTCTGAGAG GCTGAGGTGG GCAGATCATC TGAGGTCAGG AGTTCGAGAC CACCCATGGT CAACATGATG AAACCTCGTC TCTACTAAAA GTACAAAAAA TTAGCTGGAC ATGGTGGCAG GTGCCTGTAA TCCCAGCTAC TTGGGAGACT GAGACAGGAG AATTGCTTGA GCCTGGGAGG CGGAGGTTGC ATTGAGTCAA GATCGTGCCA TTGCACTCCA GCCTGGGCAA TAAGAGCGAT GCTCCGTCTC AAAAAAAAAA AAAAAAAAAA AAGAACTTAT ATTTTCAGAT TGTGTGGTTC CTTTACTAAC TGAATTTAAA TTATTTGTAG TCAATTTTAA ATGCTCTTGT ATTTT AAAGC CACTGTACTC CAGCCTGGGT GACAGAGTGA AACCCTTAAT TCAAAAAAAA

AAAAAAAAAA AAGAAAAGCT GGAATATTGG CAAAATCAAG TAACTAAGAG AAAACATTAA ATTCACAGAA TACATTATTA CATTTTAGAT ATATATGGTA TATGTTTTCT CTGAAAAGCA CAAGCATACC TTTTTTGTTT TAAATGGAGG GAACTAAAGA TACTTTGGTG CCAAAATGAA ACATTATTTG TAATTAATCT CTTATTGAAA TGGGTTTCTA ACTTTAGCTT TGAATCGTAA TCTTTCAAAT TTCTTGTACT CATAGTCACT TGATGATTCT CTATCTGAAA TATTTCTTAG AATTTGTTCT TGACCACCAG AAAAAGATTC AACTGTTACA TAGATGAAAA TGGATGTTGA GTGTTAACAG GCCTATGGGA AACAGTATTT TCTTTAGCTA CATTGTATTG TTGACTGTGT TGCTATTCTT ATAATGTTTA GGTCATTTAA ATTGTTAGAA AGATCCAAGT ATTAAGATCT AGGGTGGCTA ACTTTTCACA GACAAAAAGC TTGTTTGTAA GGTCATTTAC TATACCCTTA ATTCAGGAAG

GTTAGCTTGA ATTGGGTCAA AAGGAAACTG GTTAGAAAAT AAGTGAGTAG TGAATAGGCG ATTCAGTGCA AATTCCTTCC AGAAAATACC CTTGTAAATG ACTGTATGAA TGTGGATTCT TCAAGACAGT CAAATTTATT GTGCGAAAGT AATACTTTTA TTTTTTGCAT CTCTAAAACA TGAACTTTGA GTGATTTTTT AAAAAAATTG ATGCTATTAA ATAGATTCAA ACCATAGAAA TGGAAAATAA ATTTCTGTTT GGGGCTTTTG GGGGGATTAT GTTGTAAAAA TACCTTTTCT CTGTATTTTG TGCTTAATTA GGTACAATTG TTAAGCTAGA TGATAGCCTG TGGATGTTAC TAGTGCAAAA TCAAATTATC GTATTGTGTT TTCTCTGTAA AGTTTTGTCT TGTCTTTTCT AGTGATTTCT CTTATTCCTG TTTATTACTT GATTTGTTTT TACAGACTGT GAAATTATTC GATGACATGA TGTATGAATT AACCAGTCAA GCCAGAGGAC TGTCAAGCCA AAATTTGGAA ATCCAGACCA

CTCTAAGGAA TATTTTACAA GTAAGTCAAA TGTATTAGAA AGCAGGAGAG AGAGGGAGCT TAAAGAATGT CAAAATTTTT ATACTGATAC TGATTAGCTA TGTATTCTTA TGTAATGGCC TAATGTTGGA ATTAAATTTA TAGAATTAAA GACGTGAATA TAGAAACATG AATTCTGAAT AATAAACTCT TATAAGAAGA GAAGTCATCA AGCTAGCTGA CCCTACCTGT ATTTTCAAGG ATATGTGTGG AACACCTGCC ATGTGTTTTG AAGTTTGTGT TAGTATTCTA AATGGCTAGA CAGTTGTTCC AGTATTTGTA GTTCTGATAG ACTAAAGTTC TGTGAAAAGA GGAAGAGACT GTGTTTTGTT CATTGCTGTA TTTGTAGCAC CCAGCATGCT GACTAATACC TTTTCAGTGC ACAAAAAATA TATTCTAAGT GAAATTTCCT TCCTTATTCA CAGACAATGG TGCAGCTCTT AGGAGCTCTC ACAGGATGTG TTCAGCATAT CTGTGCCACA CAGGAATCCA TCATTTTGGA AAATATTCAG AGTCTCCCCT CCTCAGTCCT TCATATAATT AAAAGCACAT TTGTGCATTG TAAGGTGAGT AAAGGTCTAA TTATACTTTG AATGGTATAT AATCAATGTG CATAGGGGCT ATTGTTGCAA

TTTAAGGAAG TCATTAAAAG TGGCTTTTTG GGGTTTTTTA GTTTTATCTT ATTTCCCCTC TATAAAGAAA GAAGTTTTAA GAATTTGTGT TGAGACAGAC ACAGGGATCC TGAAATAGTT ATGTCATGTT GCATTGACCA ATATTCAATT ACCATTATGA TTAGATGTCA GAACTTCCTT TTATAAAGGA AAGTTAATCC TTATTTAGTC CATCTCTACA

TGCCAGAGGT AGCCTTGAGG CACAAAAGCT TGCCTAGAAT TTATGGGTCA CAGACAGTTT TAATATTGCT ATTTGTTGGG CGAATGAAAA TCACTAGTTA ATTAATACCT CTCTTTGCTG ATAGGATGCT AAAAATGTCA CGCACCTGGC CTAATGTTAC CCTTTTTTAG TTCTGTATTT GGAAGATCAT GGAAGTCAGA AATAATATTT TATACATGCT TGCATCTCTT GAAGCACACT ATATTTAATG GATGTTCACT AAACAATGAA TGAATATGTG ATTCAGTAAA TTTATGATCT CTAATAGTAT GAATTAAAGT AAATTTGGCT CTTGAGCTTT GATTTGTTTT TTCTCTCATT TTTATTTATC CGTAATCAGA ATAGTGAATC TGTGTATTCT GGGTGTTTAC ACCTAGTTTC AGACCTTCTC CAGGCTCTTT TCAAGGAGGC CTATTCTCTT CAAAAGCAGT TAATGGAACT GCTGGACATG GTTTGCATGG ACCCTTTAGT AGATGACAAT GATGATATTT TGAATATGGT AATAGGTGAG

TGAAGAAAAC TTTCTGCTTA GTATATGGTG ACTATAAATC ATGTATCAAT TAAAATTGTC TCTAATGATT CATGTTATTT TCTTACTAAT TATGCATTAA AATTGATTTA AATCTTACCA AATAAATTTT TAATCTTGAA ATTTGGAATT TGTAAAATTT ATTTTGGGTA CCTTAACCTA GATTTGCGTA TTTAGTTACT GTAATTTCTC CACAATGATT AACTTATATA ACTTTATAAT CTCTGAGGTT GTCCATATTC AGAGACAATA ACTTTCACAT TTTTTTAACC ATAACTGATA TTGAGATGCA GTTTATATTT CCTTCCAGAA TACATATAAA TACGTGCATA TGTGTATGTA AATATGTCTA TTCTCATATA CATATTATAA TGAAATAACT CATTTTACAT GTGATGCACT TTATACTAGT TTATTTTTAT TTTATTTTAT TTTTTTGAGA CAGAGTCTCA CTGTGTAGCC CAGGCTGGAG TGCAGTGGCA CAATCTCGGC TCACTGCAAC CTCGCCTCCC GGACTCAAGC GATTCTCCTG

CCTCAGCCTC ATGAGTAGCT GGGATTATAG GCGTCCGCCA CCACACCTGG CTAATTTTTG TATTTTTAGT AGAGACAGGG TTTCACCGTG TTGGCCAGGC TGGTCTTGAA CTCCTGACCT CAGGTAATCC ACCTGCCTCA GCCTCCCAAA GTGCTGGGAT TACAGGCATG AGCCACCGTG CCCAGCCAAT ACTAGTTTAT TTTTAAAGAA TTGCTGGTCG TAACACACTT CATTGATTTT ATCACTCATT AATGGATTAT GAACAAGAGT TTGAAAAACA ATATAAAGGC AAAGTTTGCA TTCAAAACTT TGGTATAAAG AGAGTAAGTT GGTTTTGTGC AGTGTATCAG GCACCTGTTG CTCTGCAACA CACCACCTCA AAATCTATTT ATTCACTATT TATTTATTCA TGATTCTGTG AGTCTGCAGT TTAGGGTGGG ATGTCCTGAG ACAACTTTCT CTGATCCACC TGGGGCACTA GCTCACCCAT GTGACTTCAG TGACTTCATT CACATCTGGC TGTTGGCAGA GGCAGAAGTA CTTGAGAAAG

CCATGTGCAT CATCCAGCAG GTTCACCCTA TCTCAGATAC CTGATGCCAG TGGTTTCAGG GTTTCTAAGA GTAGCAAAAG TGTGAGCAGG TCGCTGTGTG CTAGCACTTT TCAAGTTTCT GCTTGCCTTA ATTTTATTAT TGTCCCCCGG GCCACAGCAG GTCATAGCGT TTAGCCCAGA GTCATTGTAG AAAAGTGTGG ATTCACAAAG GGCAGTCATT GTOGCCATTT TTATAAATAA TCTACCACAG ACTGAGTAAA AGCCTTGCAT GAATACCATG GATATTAATT TGAATTCTTC CTTTTTAGAT TTTCTTTCCT TAGCAATTTG TTTTGTCATT TTGGATTAGA ATTATATCTG TAGAATATTT CAGTTATAAT AGGGTACAAC TTTTATTCCA CTGAACATCT TTAGTTTTAT TTAGGTCATC TGGTAGGTAT AAACTTCAGA AGTTAATATT CAATATTTAT AAAAACCATT AACAAGTGTG ACACTTAAAT AGTTTAAATA ATTCTTTTGA CACAACTGTT TCCAAGTTGT GTTACGTATT

TTAATTCAAT CAAATGTTGA AATTGTTCAG TAGATAGTTT TAATTATAGG AGAAACTCAC CCCCATGACA TTTGGATGTC TTAAAAGTTC TGTTATCTTT CTTTGCAGTT ATTCATTCTT TATTGGATAT CTGCTCTGTT ATTTCCAGTA TGGACCATGC ATTTCATGCC AATACTTGGA AGTTTATAAT TAAGTAAGTT TGTTTGTTAT TTTTTACTTT TTAGAAAATG TTTTCCATAT TCCCCAATCT TAATTATTCA TGATTCTTTA GATTGCATTT AAAACATTTT GTGTGAATTT AATGTTCACT GACACTGCTG TCTGATAATC CAGATATTCT ACATGTAGCT CTCAAGCCAA ATTGGACTTC TTTACCCTGT GGCCTCTAAA ATTAAAAAAA ATGTTCTTCC TAGTTAGCTA GTACTTCAGA AATAATGGGC CATGGGCCAG ACTAGAACTT AACCACTTTT CTTCTGCTAC TGTTGTTTAA CCAGCTATCA AGTATCCTAT TTCTAGGATT AGATAAATTG ATAACTATAA TTAAAACTGA

ATATAATCTT TTCATTAGGT ACTTTTAAGT TGTTCACACT TAATTCCATT TGTACAGTAA TTTTAACTTT CTGAAACTGA AGCATTTTAA AGGGTCACCA GGGATAGTGC CTGTAGCATT CATCAGATTC TTAGGGGTGA GAGGAGATGT GGTTGAGATG TAAAAATGGT TAAGAATATC TACTTTATAC ACATACATAA AACATTAAAG GTCAGTGTAT TTTCAGGTCT TAGGTACTTT TCTTGTACTA CCAGGACATT AAGTTGCCAT TCAGTGGTTA AGAGTGTTGC CTGGGAGCTG TATCACATGT GCTTAAATCC ATTCTTGAAA TCATTTACTC CTTCTGAGCC CTTGGGCTAT TTGGTTAATT TCTCTGAACG TTAGTTTGCT CATCTGAAAA TGGAAATAAT AATAGCAACT TCTTGACAGG GTTATAGTGA GAATTGAGTT CATCACTGTG AAATGCTTAG AAATGTGCAT GACACATAGT TAATACTCAA GGAATTAGCC ACATCACTAT CATCATCACT GATTATCTTC CACTCTTACC

CTCTTCCAGT TCATTTTCTG CCCAGCAGAA TGATCTTTTA AAAAGTAAAT CAGATCATGT TACTCTATTG CTTGAAGTCT ATCCCATTTG ATTAAGAATA ACAACCTAAT CCTCTGTGGA TGCTGCCTCC TTCACCAGCC TGTCTCATGC TGCTCTCCCT ACTCTTAGTT CCTCAAACAT ACCAAACTCT CCTGTCCCAG AGTCTTTTCG TGGTTTTTCC ATCTGCCTAG GATGCTTCTC TCTCCTATTT TGTGTACCTT GCTAACTCCT GCTTACTGTC TTTCAGTTCT CAGCTTAAGA GTTATATCTT CATGATAACA TTCTTTGATA TCCTTACCCT AAGATTAAGT TAGATTGATA TCCTTACCCT AAGAATAAGT TAGATTAGGT CTCTCTATTG TAGCACCTTA GACTCTGTCA TTTGACAAAT CACAGCCCTA ATTAATTATT CTTAAAATTA TTTAACATTC TCTCTCATGC TAGACCACAA GTTTCATGCA GGTAAGGCGG AGATTGTGTC CATTTGTTTG ACCCCTTTGT CTCCAGGGCC

TGGTAGAATG CCTCATACAT AGTAAGAATT CAATTAATAT TTTACACAGA GAAAAAATTA GCAACTTATT TAAACAAATA TAACTGCTTC AGAGGTAAAC TGGGCACATC TTAGTTATAT TATGTGATAT ATGATGCTTT TTGATTGTTT TTTTAAATGT TCTACAAGGT AGATATTGTT AGAGGTCCTA AGTTACTTGA TGTGTTACTT GTGGTGATTG TATTCTTTTC TTTTTATTCA TTTAGGCAGA GCCTTAAGCA CCAGTCCATA ATAAAAAGCC AGTTGAAACA CAAAGATATA ATTACTAGCT TGTGTGAAGA CATTCTTTTC TCCTTCCATT CTTGTTTACA GTTAGCTGAG CAGATGACAC AGTCAGATGC ACAGGTAAAA TTTGGGCTAA TAGCATTTTA AACAGCAACT CTTATTTTCT TTGGCAGTTA GTAAATCTCA TTTGAATGTC TGGGTCAGTC TATTTAAGAG GATTTTAATT TATTTCATTT GGGTGTTTTT TTTTGATCTG TGGGATTATT TATATCCCAT AATTACTTTT

CACCCAGAGC ATTGTATTAG ATTCCTAACT GCTGTCATTG CCTCTGGGGT CTGCCTGGCT CCCTCTTTGC TTGGTAACTG GTTGGTCACA GCATTCTTCT CAGAATCCTT TCATTCTTTT CTGCATGAGA ACAAAAATTC TTTTGTTCAT ATTTGTATAA GATCTGATAT AGCTGCAATC AATCTTGCAT TTTTTCTTCA CCAACGCATT GCGACCTTTA GGGATACAAG TATGTTTGTG CATGTATATG TATGTATCAG TCTTTTAAAT TTGATATAGT CATACATTTG TTTTTATTTT GAAAAGTTAG AGTGTTGAAT TGGTATCCCA TTTATGAAAC ATTATATTCT AAAAATTTGT AGTACGATTA TTGGGAATTA TAACTCATTT TCCTGTAACA CTGTTATACA TAGTACCTTT TGCTTTCAGA CTAGCCCTCA TATATGTCAT TTGTTTTTTT TTTTTTTGAG ATGGCGTCTC ACTCTGTCAC

CCAAGCTGGA GTGCAGTGGT ATGACCTTGG CTCACTGCAG CCTCTGCCTC ACGGGTTCAA GGGATCGTTC TGCCTTAGCC TCCTGAGTAG CTGGGATTAT AGGCGCCTGC CACCACGCCT GGCTAATTTT TTTAGTAGAG ACGGGGTTTC GCCATGTTGG CCAGGCTGGT CTCGAACTCC TGACCTCAGG TGGTCCACCC GCCTTGGCCT CCCAAAGTGC TGGGATTACA GGTGTGAGCC ACCGCGCCCA GCCTATATGT AATAATTTTA ATGGGACCAT GAATTGAATA TTTCTTCCTT GAATAGCAAT GACATAGCCC CTTCTATTGT ACATCTGCAA GCTGATACAG GGAATTCCTT TGTACCTGCG CTCTTCCCTG CCAGTCAGCT ATGGGGGTGA AAGTGTAGGG GTTCATCCAA GTCCTAAAAC TGGTAGCAAC TCCTAGGGCA GGGCTGATCT GGAAGGACAG ACCCTAGGGG AGGGTGGAAC TTTAAAAAGA AGTTCTGAAG GTAGTAAGAA GGAAATGAGG AGTAGTGTTA

GGAAGGGGCT AACTTTTTTC TTCTTGCTTC TCTTCTTTAT CTCACCTGCC CCTCCCCTTG TATCCCTTCT TCCTTTTTCC CTTTCCTTTT TTGTCCTCAC TTCATTCGTG CATCCTTTCT GATTCCTCTT ACCTTGCTAA AAGGAGAAGT TTGTTTGGGT ATCCTATATC AATGGCAGGA AGGTTGTTTT CTTCTTTACC TTTATCCTAT AGATTCATAT TCTCAACACC AACCTCCTCC TTTTTCAGTT TCCTTCTTGC TTCTCTTGAC ACCACAGAGT TTGCAGCTAG TACTTGGAGA GGAAAATTAA ACAGAGATAC TTGGACCAAG AGTAAGATGA AGAAAGTCTA AACAACAGTA TAGTCTATAG TGGCAAGAGA GAGTATGGGG GCTGCTTAGC CAGGGTGGCT GTACATAAAG TATATCTTCA GTTTATATAA ACTGCTTATA GATGGAAATC AGAAAATTTA AATTCTCTTA ACTGTCCAAG AAAATTCTCA TTTTTTCAAA TTTGGGACTG ATAAATGTGA CCAGTTCTGC TTACTGTCCA

TTGCCTGAAA TGGAGCTTTG AGGTGGACTG TATAATTTCT TCAATCTTAA CTCCAAATTC TGATCAGCGA CGCCCTCTGC TGTTCACTAT TAATATTTAT TTACCAATCA AAGTAAAGTA TTGAAGTTTT CCTGGCAGTT TTCACTTTGT GTTTTAGTCC ATTTAGGCTG CTATAACAAA ATCCCTTAAA CTGGGTAAGG GATTATAAAT ATTAGAAATT TATCTCTCAC AGTTCTGGAA GCTGGGAAGC CCAATATCAA GGCACCAGTA GATTTGGTGT CTAACGAGGG TGTGCCGTCT GCTTCAAAAA TGGCCCCTTG TTGCTGCATC CTCACTTAGT GCAAGGGGCA AGACAGCTCC CTTCAACCTC TTTTATAAGG GCACTTATGT CATTCATGAG GGCAGAGCCC TCATGACTTA ATCACTTCCC CAAAGGCCCC ACCTCTTAAT AGTATCACAT TGGGTGTTAG GTGTCTGGGA GGACACCAAT CTTCAAGCCA TATCATCTCA CTTGGAAAAA AGTCAAAATA AAACCAGTAG ATTTAATTAA

TATTACACTA TTTATAGAAG CATGTGATGT ATCATTCCTT GTATTAATTT CCTGGGGTTG CCGTAACAAG TTACCACAAA CTAGGTGGCT TAAAACAATA GAATTTTATT TCTCTGGAAG

CTGGCAATCC TTAGCTTACT TTGGCTTTCT GTGTCTTCAC ATCATCTTTT TATAAGAACA CCAGTGATAG TGATTAAGGG CATACCTTAC TTTAATATGA CCTCATCTTA ACTAATTATG TCTTCAATAA CCCTATTTCC AAATAAGGCC ACATTCTGAA GTATTGGGAG TTAGAACTTA AAGCTTTTTG GGAGGGACAC AGTTCAACCC ATAACAACCC CTAAAATCGA TATTTATTCT CAATTAAGTC TTGAAATTGG TTTCAAAAAG AGAATATTCT ATTAGAGTTT TTAATGTATA GTTTTAACAT ATAGTTCTTT AGCCCCCAAT

TTTTTTTTTT xxxx x _{τττττττττ}χ χ_TTTTGAGAC GGAGTCTCGC TCTGTCGCCC AGGCCGGACT GCGGACTGCA GTGGCGCAAT CTCGGCTCAC TGCAAGCTCC GCTTCCCGGG TTCACGCCAT TCCCCTGCCT CAGCCTCCCG AGTAGCTGGG ACTACAGGCG CCTGCCACCG CGCCCGGCTA ATTTTTTTGT ATTTTTAGTA GAGACGGGGT TTCACCTTGT TAGCCAGGAT GGTCTCGATC TCCTGACCTC ATGATCCACC CGCCTCGGCC TCCCAAAGTG CTGGGATTAC AGGCGTGAGC CACCGCGCCC GGCCTGCCCC CAATTATTTA GTTTTTCTAT AAACAGGGAA ATTTATTTGT GTGGCCCTTA GAACTAATTT AATTTCCACT CTAATTCCTA CTTATGTTTA TATAATGCTT TTAGAAATTT GTATTATTCA GAAAATAAAC ATATACTATT GTATCTGTTG CCTACACTTA GATTTTATTG CCTGCTATAT TTAAATTTTA TTAGTATTTT AATTGTTTTA TTAAAGAAAG

AATGTGCCTG TAATCTCAGC ACTTTTGAGA GGCCAAGGCA GAAGGATTGC TTGAGCCCAG GAGTTTGAGA CCAGACTGAG CAACACAGGG AGACCCCCAT CTCTACAAAA AATAAAAAAA TTCTCCAGGC CTCATGGCAC ATACCTGTAG TTCTAGTTAC TTGGGAGACT GGGGTGGGAG GATGCATTGA GCCCAGGAGA TTGAGGCTGC AGTGAGCCAT GATCAGGCCA CTGTACTCCA GCTTGGACAA CAGAGTGAGA GCTTGTCTAG ATAGATAGAT AGATAGATAA TCTAAATAGA TAATAGACAG ATTATCTAAA TAGATAATAG ACAGATTATC TAAATAGATA ATAGACAGAT TATCTAAATA GATAATAGAC AGATTATCTA AATAGATAAT AGACAGATTA TCTAAATAGA TAATAGACAG ATTATCTATC TAAATAGATA ATAGATTATC TAAATAGATA ATAGATAGAT AGATTAGATA GATAGATAGA TAGATAGAGC TTGGACAACA GAGTGAGAGC CTGTCTAGAT AGATAGAAAC

AAAGAAAGAA AGAAAGAATG GTGCTCATAT TTTAAAGCAT TGAAAAATGG TCTTCCTTGC TTATATTACC CACACCTTCT TTGTTGGCAT TAAGATGCAA ACTTTGTTTT AAACAGTTGA GTAAATCAAA GATGGGACTG TTAAGTTATT TGTGTTATTT ACCTGCTTTT TGAAAATGTA AAAATAAAAC TCTAGGTTTA ATTAGTAGTA TGCTATTTAG TAATGAAGTA AAGCTAGAGG CTTCGAACAA ATCTTGTGTA ATTTCCTCTT GAATGAGAGA GAAAATTTAA AGTAAGCAAA CAAATAAGTT GTGTGTCACC ACTCATTCAG TCATTTAACA AGTATTTCCA GAGTACTTAT TCTGTGCCAG GAAATGTTGT AGGTGCCCTC AACAACTTAG AGTCTAGCCT GAGACACAAG TAAGTAGGTA ATTATTATAG AATGGTATGA TCTTTGGAGG ACTGGGTATT GGCTGGCTCA TGGGAGTACA AGATAGGTAC CCAGTGATGA AGTCAGGAAA GGTTTCTTAT GGTGATATGA TGACGTCTAT

GCTGATTATA AGGTCAGTGT AGAATAAACT TTGTGCTTTT AAATTTGCAT AGCACTGTAT TAGAGAGTTC ATCTTCAAAA TAATCGAAAA GGCTGAGTGT GGTGACCCAT GGCTGTAATC CCAGCACTTT GGGAGGCCGA GGTGGGCAGA TTGCTTGAGC TAGGAGTTCG AGACCAGGCT GGCCAACATG GTGAAACCCC GTCTCTACTA AAAATACAAA AATTAGCCAG GAGTGATGGT GCGCACCTGT AATGCCAGCT ACTTGGGAGG CTGAGGCAGG AGGATCACTT GAACCCAGGA GGTGGAGGTT GAAGTAAGCC GAGGTCATGC CACTGCACTC CAGCCTGGGC AACAGAGTGA GACTCCATCT CAAAAAAAAA AAAAATGATC AAAGAAAGGT GAATTTTCAT CTACCCTATT TCTGCTGAGG AAAATGGACT ATTTTCAAAT ATTTTTAATA AGGGTCAAAA TGAGGGATC-3' (FRAG NO J(SEQ ID NO 11849)

5'-CCTGAGACAG AGGCAGCAGT GATACCCACC TGAGAGATCC TGTGTTTGAA CAACTGCTTC CCAAAACGGA AAGTATTTCA AGCCTAAACC TTTGGGTGAA AAGAACTCTT GAAGTCATGA TTGCTTCACA GTTTCTCTCA GCTCTCACTT TGGTGCTTCT CATTAAAGAG AGTGGAGCCT GGTCTTACAA CACCTCCACG GAAGCTATGA CTTATGATGA GGCCAGTGCT TATTGTCAGC AAAGGTACAC ACACCTGGTT GCAATTCAAA ACAAAGAAGA GATTGAGTAC CTAAACTCCA TATTGAGCTA TTCACCAAGT TATTACTGGA TTGGAATCAG AAAAGTCAAC AATGTGTGGG TCTGGGTAGG AACCCAGAAA CCTCTGACAG AAGAAGCCAA GAACTGGGCT CCAGGTGAAC CCAACAATAG GCAAAAAGAT GAGGACTGCG TGGAGATCTA CATCAAGAGA GAAAAAGATG TGGGCATGTG GAATGATGAG AGGTGCAGCA AGAAGAAGCT

TGCCCTATGC TACACAGCTG CCTGTACCAA TACATCCTGC AGTGGCCACG GTGAATGTGT AGAGACCATC AATAATTACA CTTGCAAGTG TGACCCTGGC TTCAGTGGAC TCAAGTGTGA GCAAATTGTG AACTGTACAG CCCTGGAATC CCCTGAGCAT GGAAGCCTGG TTTGCAGTCA CCCACTGGGA AACTTCAGCT ACAATTCTTC CTGCTCTATC AGCTGTGATA GGGGTTACCT GCCAAGCAGC ATGGAGACCA TGCAGTGTAT GTCCTCTGGA GAATGGAGTG CTCCTATTCC AGCCTGCAAT GTGGTTGAGT GTGATGCTGT GACAAATCCA GCCAATGGGT TCGTGGAATG TTTCCAAAAC CCTGGAAGCT TCCCATGGAA CACAACCTGT ACATTTGACT GTGAAGAAGG ATTTGAACTA ATGGGAGCCC AGAGCCTTCA GTGTACCTCA TCTGGGAATT GGGACAACGA GAAGCCAACG TGTAAAGCTG TGACATGCAG GGCCGTCCGC CAGCCTCAGA ATGGCTCTGT GAGGTGCAGC CATTCCCCTG CTGGAGAGTT CACCTTCAAA TCATCCTGCA ACTTCACCTG TGAGGAAGGC TTCATGTTGC AGGGACCAGC CCAGGTTGAA TGCACCACTC AAGGGCAGTG GACACAGCAA ATCCCAGTTT GTGAAGCTTT CCAGTGCACA GCCTTGTCCA ACCCCGAGCG AGGCTACATG AATTGTCTTC CTAGTGCTTC TGGCAGTTTC CGTTATGGGT CCAGCTGTGA GTTCTCCTGT GAGCAGGGTT TTGTGTTGAA GGGATCCAAA AGGCTCCAAT GTGGCCCCAC AGGGGAGTGG GACAACGAGA AGCCCACATG TGAAGCTGTG AGATGCGATG CTGTCCACCA GCCCCCGAAG GGTTTGGTGA GGTGTGCTCA TTCCCCTATT GGAGAATTCA CCTACAAGTC CTCTTGTGCC TTCAGCTGTG AGGAGGGATT

TGAATTATAT GGATCAACTC AACTTGAGTG CACATCTCAG GGACAATGGA CAGAAGAGGT TCCTTCCTGC CAAGTGGTAA AATGTTCAAG CCTGGCAGTT CCGGGAAAGA TCAACATGAG CTGCAGTGGG GAGCCCGTGT TTGGCACTGT GTGCAAGTTC GCCTGTCCTG AAGGATGGAC GCTCAATGGC TCTGCAGCTC GGACATGTGG AGCCACAGGA CACTGGTCTG GCCTGCTACC TACCTGTGAA GCTCCCACTG AGTCCAACAT TCCCTTGGTA GCTGGACTTT CTGCTGCTGG ACTCTCCCTC CTGACATTAG CACCATTTCT CCTCTGGCTT CGGAAATGCT TACGGAAAGC AAAGAAATTT GTTCCTGCCA GCAGCTGCCA AAGCCTTGAA TCAGACGGAA GCTACCAAAA GCCTTCTTAC ATCCTTTAAG TTCAAAAGAA TCAGAAACAG GTGCATCTGG GGAACTAGAG GGATACACTG AAGTTAACAG AGACAGATAA CTCTCCTCGG GTCTCTGGCC CTTCTTGCCT ACTATGCCAG

ATGCCTTTAT GGCTGAAACC GCAACACCCA TCACCACTTC AATAGATCAA AGTCCAGCAG GCAAGGACGG CCTTCAACTG AAAAGACTCA GTGTTCCCTT TCCTACTCTC AGGATCAAGA AAGTGTTGGC TAATGAAGGG AAAGGATATT TTCTTCCAAG CAAAGGTGAA GAGACCAAGA CTCTGAAATC TCAGAATTCC TTTTCTAACT CTCCCTTGCT CGCTGTAAAA TCTTGGCACA GAAACACAAT ATTTTGTGGC TTTCTTTCTT TTGCCCTTCA CAGTGTTTCG ACAGCTGATT ACACAGTTGC TGTCATAAGA ATGAATAATA ATTATCCAGA GTTTAGAGGA AAAAAATGAC TAAAAATATT ATAACTTAAA AAAATGACAG ATGTTGAATG CCCACAGGCA AATGCATGGA GGGTTGTTAA TGGTGCAAAT CCTACTGAAT GCTCTGTGCG AGGGTTACTA TGCACAATTT AATCACTTTC ATCCCTATGG GATTCAGTGC TTCTTAAAGA GTTCTTAAGG ATTGTGATAT TTTTACTTGC

ATTGAATATA TTATAATCTT CCATACTTCT TCATTCAATA CAAGTGTGGT AGGGACTTAA AAAACTTGTA AATGCTGTCA ACTATGATAT GGTAAAAGTT ACTTATTCTA GATTACCCCC TCATTGTTTA TTAACAAATT ATGTTACATC TGTTTTAAAT TTATTTCAAA AAGGGAAACT ATTGTCCCCT AGCAAGGCAT GATGTTAACC AGAATAAAGT TCTGAGTGTT TTTACTACAG TTGTTTTTTG AAAACATGGT AGAATTGGAG AGTAAAAACT GAATGGAAGG TTTGTATATT GTCAGATATT TTTTCAGAAA TATGTGGTTT CCACGATGAA AAACTTCCAT GAGGCCAAAC GTTTTGAACT AATAAAAGCA TAAATGCAAA CACACAAAGG TATAATTTTA TGAATGTCTT TGTTGGAAAA GAATACAGAA AGATGGATGT GCTTTGCATT CCTACAAAGA TGTTTGTCAG ATGTGATATG TAAACATAAT TCTTGTATAT TATGGAAGAT TTTAAATTCA CAATAGAAAC TCACCATGTA

AAAGAGTCAT CTGGTAGATT TTTAACGAAT GAAGATGTCT AATAGTTATT CCCTATTTGT TTTCTTCTGT ATGTTAGGGT GCTCTGGAAG AGAGGAATGC CTGTGTGAGC AAGCATTTAT GTTTATTTAT AAGCAGATTT AACAATTCCA AAGGAATCTC CAGTTTTCAG TTGATCACTG GCAATGAAAA ATTCTCAGTC AGTAATTGCC AAAGCTGCTC TAGCCTTGAG GAGTGTGAGA ATCAAAACTC TCCTACACTT CCATTAACTT AGCATGTGTT GAAAAAAAAA GTTTCAGAGA AGTTCTGGCT GAACACTGGC AACGACAAAG CCAACAGTCA AAACAGAGAT GTGATAAGGA TCAGAACAGC AGAGGTTCTT TTAAAGGGGC AGAAAAACTC TGGGAAATAA GAGAGAACAA CTACTGTGAT CAGGCTATGT ATGGAATACA GTGTTATTTT CTTTGAAATT GTTTAAGTGT TGTAAATATT TATGTAAACT GCATTAGAAA TTAGCTGTGT GAAATACCAG TGTGGTTTGT

GTTTGAGTTT TATTGAGAAT TTTAAATTAT AACTTAAAAT ATTTTATAAT TTTTAAAGTA TATATTTATT TAAGCTTATG TCAGACCTAT TTGACATAAC ACTATAAAGG TTGACAATAA ATGTGCTTAT GTTT-3'(FRAG NO J(SEQ DD NO 11848) 5'-CCT TGC CTG CTG G-3' (FRAG NO 1739) (SEQ ID NO 11121) 5'-GTT GTC CC-3' (FRAG NO 1740) (SEQ ID NO 11122) 5'-GTT CTT GGC TTC TTC TGT C-3' (FRAG NO 1080) (SEQ ID NO 10457)

5'-GGC TGG TGG-3' (FRAG NO 1083) (SEQ DD NO 10461) 5'-CGT TGG CTT CTC GTT GTC CC-3' (FRAG NO 1081) (SEQ ID NO 10458) 5'-TGT GGG CTT CTC GTT GTC CC-3' (FRAG NO 1082) (SEQ TD NO 10459) 5'-CCC TTC GGG GGC TGG TGG-3' (FRAG NO 1083) (SEQ ID NO 10460) 5'-GGC CGT CCT TGC CTG CTG G-3' (FRAG NO 1084) (SEQ DD NO 10462)

Human P Selectin Fragments

5'-TTT TCT CTT TCG CTT TCT TTT CGT CTC CTG TTC CTC CTT TT TTG CTG TTT TTT CTC CTT CTT CTC TCC TTT CTT TTC-3' (FRAG NO 1741) (SEQ DD NO 11123) 5'-TCC TTT CTT TTC-3' (FRAG NO 1742) (SEQ DD NO 11124)] 5'-CTC CTT TT-3' (FRAG NO 1743) (SEQ ID NO 11125) 5'-TTT TCT CTT TCG CTT TCT TTT CGT CTC CTG TTC CTC CTT TT-3'(FRAGNO 1085)(SEQ DD NO 10463)

5'-TTG CTG TTT TTT CTC CTT CTT CTC TCC TTT CTT TTC-3' (FRAG NO 1086) (SEQ DD NO 10464)

Human Endothelial Monocyte Activating Factor

Nucleic Acid & Antisense Oligonucleotide Fragments

5'-TTT TCT CTT TCG CTT TCT TTT CGT CTC CTG TTC CTC CTT TT TTG CTG TTT TTT CTC CTT CTT CTC TCC TTT CTT TTC-3' (FRAG NO 1744) (SEQ DD NO 11126) 5' -CC TTT CTT TTC (FRAG NO 1745) (SEQ ID NO 11127)

5'-CTG TTC CTC CTT TT-3' (FRAG NO 1746) (SEQ ID NO 11128)

5'-TTT XCX CTT TCG CTT TCT TTT CGT CTC CTG TTC CTC CTT TT-3 '(FRAG NO 1087)(SEQ ID NO 10465)

5'-TTG CTG TTT TTT CTC CTT CTT CTC TCC TTT CTT TTC-3' (FRAG NO 1088) (SEQ ID NO 10466)

Human IL3 Nucleic Acid and Antisense Oligonucleotide Fragments 5'-CTC TGT CTT GTT CTG GTC CTT CGT GGG GCT CTG TGT CGC GTG G GTG CGG CCG TGG CC GGC GGB CCB GGB GTT GGB GCB GGB GCB GGB CGG GCB GGC GGC

TCB TGT TTG GBT CGG CBG GBG GCB CTC (FRAG NO 1747) (SEQ ID NO 11129)]

5'-G GBG GCB CTC-3' (FRAG NO 1748) (SEQ ID NO 11130)

5'-GT GGG GCT CTG-3' (FRAG NO 1749) (SEQ ID NO 11131)

HUMIL3AAS1 5'-CTC TGT CTT GTT CTG GTC CTT CGT GGG GCT CTG-3' (FRAGNO 1089)(SEQ ID NO 10467) HU IL3AAS2 5'-TGT CGC GTG G GTG CGG CCG TGG CC-3' (FRAG NO 1090) (SEQ DD NO 10468)

GGC GGB CCB GGB GTT GGB GCB GGB GCB GGB CGG GCB GGC GGC TCB TGT TTG GBT CGG CBG GBG GCB CTC (FRAG NO 1091) (SEQ ID NO 10469)

Human IL3 Receptor Nucleic Acid and Antisense Oligonucleotide Fragments

5'-TCT GGG GTG TCC TGG CCT TCG TGG TTC CTC TTC CTT CGT TTG CCG TCC GCG GGG GCC CCC GGG CCT GGC TGC GCT CCT GCC CCG CCT CTT TCC CGG GCT CTT

GCG CTG GGG GGT GCT CC CGT GTG TTT GCG CCC TC CTC CTG GTC GCG CTT GTC GTT TTG GGG CCG GCT TTG CCC GCC TCC CGG CGC CTG GCC CGG CC TTC CTG GGC TGC GTG CGC GTT CTG TTC TTC TTC CTG GCT CTG GGG TGT CCT GGC CTT CGT GGT TCC TCT TCC TTC GTT TGC CGT CCG CGG GGG CCC CCG GGC CT GGC

TGC GCT CCT GCC CCG CCT CTT TCC CGG GCT CTT GCG CTG GGG GGT GCT CCC GTG TGT TTG CGC CCT CCT CCT GGT CGC GCT TGT CGT TTT GG GGC CGG CTT

TGC CCG CCT CCC GGC GCC TGG CCC GGC CTT CCT GGG CTG CGT GCG CGT TCT GTT CTT CTT CCT GGC GCA GGA GAC AGG GCA GGG CGA TCA GGA GCA GCG

TGA GCC AAA GGA GGA CCA TCG GGA ACG CAG CTC CGG AAC GCA GGA CAG AGG TGC C GC BGG BGB CBG GGC BGG GCG BTC BGG BGC BGC GTG BGC CBB BGG

BGG BCC BTC GGG BBC GCB GCT CCG GBB CGC BGG BCB GBG GTG CC-3' (FRAG NO 1750) (SEQ ID NO 11132) GBG GTG CC-3' (FRAG NO 1751) (SEQ ID NO 11133)

5'- GCC CCG C-3' (FRAG NO 1752) (SEQ DD NO 11134)

5'-TCTGGGGTGTCCTG (FRAG NO 1092) (SEQ ID NO 10470)

5'-GCCTTCGTGGTTCC (FRAG NO 1093) (SEQ ID NO 10471)

S'-TCTTCCTTCGTTTGC (FRAG NO 1094) (SEQ ID NO 10472) 5'-CGTCCGCGGGGGCCCCCGGGCCT (FRAG NO 1095) (SEQ DD NO 10474)

5'-GGC TGC GCT CCT GCC CCG C (FRAG NO 1096) (SEQ DD NO 10473) 5'-CTCTTTCCCGGGCTCTT (FRAG NO 1097) (SEQ ID NO 10475) 5'-GCGCTGGGGGGTGCTCC (FRAG NO 1098) (SEQ ID NO 10476) 5'-CGTGTGTTTGCGCCCTCCTCCTGGTCGC (FRAG NO 1099) (SEQ D NO 10477) 5'-GCTTGTCGTTTTGG (FRAG NO 1100) (SEQ DD NO 10478)

5'-GGCCGGCTTTGCCCGCCTCCC (FRAG NO 1101) (SEQ ID NO 10479) 5'-GGCGCCTGGCCCGGCC (FRAG NO 1102) (SEQ ID NO 10480) 5'-TTCCTGGGCTGCGTGCGC (FRAG NO 1103) (SEQ ID NO 10481) 5'-GTTCTGTTCTTCTTCCTGGC (FRAG NO 1104) (SEQ ID NO 10482) 5'-GCB GGB GBC BGG GCB GGG CGB TCB GGB GCB GCG TGB GCC BBB GGB GGB CCB TCG GGB BCG CBG CTC CGG BBC GCB GGB 5'-CBG BGG TGC C (FRAG NO 1105)

(SEQ ID NO 12488)

Human IL-4 Nucleic Acid and Antisense Oligonucleotide Fragments

5'-CTC TGG TTG GCT TCC TTC GCC GGC BCB TGC TBG CBG GBB GBB CBG BGG GGG BBG CBG TTG GGB GGT GBG BCC CBT TBB TBG GTG TCG B-3' (FRAG NO 1753) (SEQ ID NO 11135) 5'-GCC GGC BCB-3' (FRAG NO 1754) (SEQ NO 11136)

5'-T TCC TTC-3' (FRAG NO 1755) (SEQ ID NO 11137) 5'-CTC TGG TTG GCT TCC TTC-3' (FRAG NO 1106) (SEQ ID NO 10484) 5'-GCCGGCBCBTGCTBGCBGGBBGBBCBGBGGGGGBBGCBGTTGGGBGGTGBGBCCCBTTBBTBGGTGTCGB 3' (FRAG NO 1107) (SEQ ID NO 10485)

Human IL4 Receptor Nucleic Acid and Antisense Oligonucleotide Fragment 5'-TCT GCC CTG TCC GCC GGC TCT TCG GTG GCT CGG CCC CGC TCC TTG TCT TGC CGC GGG TTG GTT CCT GGG CCT GGT TCT TGC GGG CGT TTC GGT CTG CTG

GCT GGT CTG GGC CCG CGG TGC GGC GGG TGG CTT GCT GTT CTG CCT GGG CTC TCC CCT CTC CTC CTT TTC TCC CTT CCT CTG TCT TGC CTC CTT CCT CTG GGT CCT CTT GGC CTG GGC GCT CTT CCC CTC GGG CGG CTG CGG GCG CTC GTG CTG CCT GGT CCG CTC CCT GGG GGT GCT CCT TCC CTT TCC CCG CTC GTG GGG TTT GCG GGG CTG GGC TGC CCT GGG GGG TCT GGG CCT TTT GGG GTC GGC TGG CTG CTG CTT CGG GCC GCC TGG GCT TCC CTG TGC CCC TTT CCT CTG CTG GGT CCC CCT CCC GTT CCA AGC TGC ACC GCA CAG ACC GGC GCT ACA GGA CAG AGC CAG GCA AGC ACC CAT GGG GAT CCA GGC CCA GCT GTT CCB BGC TGC BCC GCB CBG BCC GGC GCT BCB GGB CBG BGC CBG GCB BGC BCC CBT GGG GBT CCB GGC CCB GCT G -3'(FRAG NO 1756)(SEQ ID NO 11138)

5'-TCTGCGC-3' (FRAG NO 1757) (SEQ DD NO 11139) 5'-CCT GCT CCT GGG G (FRAG NO 1758) (SEQ ID NO 11140) S'-TCTGCGCGCCCCTGCTCC (FRAG NO 1108) (SEQ DD NO 10486)

5'-CGCCCGGCTTCTCT (FRAG NO 1109) (SEQ ID NO 10487)

5'-CGTGTGGGCTTCGG (FRAG NO 1110) (SEQ DD NO 10488)

5'-CCCCGCGCCTCCGTTGTTCTC (FRAG NO 1111) (SEQ DDNO 10489) 5'-TGCTCGCTGGGCTTG (FRAG NO 1112) (SEQ DD NO 10490)

5'-GGTTTCCTGGGGCCCTGGGTTTC (FRAG NO 1113) (SEQ ID NO 10491)

5'-TCTGCCGGGTCGTTTTC (FRAG NO 1114) (SEQ DD NO 10492)

5'-GGGTGCTGGCTGCG (FRAG NO 1115) (SEQ DD NO 10493)

5'-CTTGGTGCTGGGGCTCC (FRAG NO 1116) (SEQ DD NO 10494) 5'-GGCGGCTGCGGGCTGGGTTGGG (FRAG NO 1117) (SEQ ID NO 10495)

5'-CTTGGCTGGTTCCTGGCCTCGGG (FRAG NO 1118) (SEQ ID NO 10496)

5'-CCTCCTCCTCCTCCTCGCTCCCTTTTTCTTCCTCT (FRAG NO 1119) (SEQ ED NO 10497)

5'-TCCCTGCTGCTCTC (FRAG NO 1120) (SEQ ID NO 10498)

5'-TGCCCTCCCTTCCCTCCTGG (FRAG NO 1121) (SEQ ID NO 10499) 5'-GGTGCCTCCTTGGGCCCTGC (FRAG NO 1122) (SEQ ED NO 10500)

5'-GGCTGCTCCTTGCCCC (FRAG NO 1123) (SEQ ID NO 10501)

5'-CTCTGGGTCGGGCTGGC (FRAG NO 1124) (SEQ ID NO 10502)

5'-GGGGCGTCTCTGTGC (FRAG NO 1125) (SEQ DD NO 10503)

5'-CTGGCCTGGGTGCC (FRAG NO 1126) (SEQ ID NO 10504) 5'-GCCTCTCCTGGGGGGGTGGCTCCCTGTCC (FRAG NO 1127) (SEQ DD NO 10505)

5'-CCTTTTCCCCCGGCTCC (FRAG NO 1128) (SEQ ID NO 10506)

5'-GTGGGGGCTTTGGC (FRAG NO 1129) (SEQ ID NO 10507)

5'-GGG GGT CTG TGG CCT GCT CCT GGG G (FRAG NO 1130) (SEQ DD NO 10508)

5'-AGGGGTCTGGGGCCCTC (FRAG NO 1131) (SEQ ID NO 10509) 5'-TTTTGGGGGTCTGGCTTG (FRAG NO 1132) (SEQ DD NO 10510)

5'-GCCTGGCTGCCTTCC (FRAG NO 1133) (SEQ ID NO 10511)

5'-GGGGCCTGCCGTGGGGC (FRAG NO 1134) (SEQ ID NO 10512)

5'-TGTCCTCTGTTGCTCCCCTT (FRAG NO 1135) (SEQ ID NO 10513)

5'-TGCCTGCTGTCTGG (FRAG NO 1136) (SEQ ID NO 10514) 5'-GGTTCCCGCCTTCCCT (FRAG NO 1137) (SEQ DD NO 10515)

5'-GTT CCC AGA GCT TGC CAC CTG CAG CAG GAC CAG GCA GCT CAC AGG GAA CAG GAG CCC AGA GCA AAG CCA CCC CAT TGG GAG ATG CCA AGG CAC CAG GCT

G (FRAG NO 1138) (SEQ ID NO 10516)

5'-GTT CCC BGB GCT TGC CBC CTG CBG CBG GBC CBG GCB GCT CBC BGG GBB CBG GBG CCC BGB GCB BBG CCB CCC CBT TGG GBG BTG CCB BGG CBC CBG GCT G-

3' (FRAG NO 1139) (SEQ DD NO 10517) Human IL5 Nucleic Acid and Antisense Oligonucleotide Fragments

5'-TCCCTGTTTC CCCCCTTTCG TTCTGCGTTT GCCTTTGGCG TTTTTTGTTT GTTTTCTCTC TCCGTCTTTC TTCTCCCCT GTGGGBBTTT CTGTGGGGBT GGCBTBCBCG

TBGGCBGCTC CBBGBGCTBG CBBBCTCBBB TGCBGBBGCB TCCTCBTGGC TCTGBBBCGG TGGGAATTTC TGTGGGGBTG GCATACACGT AGGCAGCTCC AAGAGCTAGC

AAACTCAAAT GCAGAAGCATC CTCATGGCTC TGAAACG-3' (FRAG NO 1759) (SEQ DD NO 11141)

5'-GCC CCG GG-3' (FRAG NO 1760) (SEQ DD NO 11142) 5'-G GGT TTC T-3' (FRAG NO 1761) (SEQ ID NO 11143)

5'-GTG GGG BTG GC-3' (FRAG NO 1762) (SEQ ID NO 11144)

5'-CCB BGB GCT BGC-3' (FRAG NO 1763) (SEQ ID NO 11145)

5'-TCC CTG TTT CCC CCC TTT-3' (FRAG NO 1140) (SEQ ID NO 10518)

5'-CGT TCT GCG TTT GCC TTT GGC-3' (FRAG NO 1141)(SEQ DD NO 10519) 5'-GTT TTT TGT TTGTTT TCT-3' (FRAG NO 1142)(SEQ DDNO 10520)

5'-CTC TCC GTC TTT CTT CTC C-3' (FRAG NO 1143) (SEQ ID NO 10521)

5'-CCT CCT GCC TGT GTC CCT GCT CCC C-3' (FRAG NO 1144) (SEQ ID NO 10522)

5'-GAG GGT TTC TGG CTT CCT CTC T-3' (FRAG NO 1145) (SEQ ID NO 10523)

5'-TGT CTC TCT GTC CTT TTG TT-3' (FRAG NO 1146) (SEQ ID NO 10524) 5'-TGT TGT GCG GCC TGG TGC TGC CCT GCC CCG GG-3' (FRAG NO 1147) (SEQ DD NO 10525)

5'-GTG GGA ATT TCT GTG GGG BTG GCA TAC ACG TAG GCA GCT CCA AGA GCT AGC AAA CTC AAA TGC AGA AGC ATC CTC ATG GCT CTG AAA CG-3' (FRAG NO

1764) (SEQ ID NO 11146)

5'-GTG GGB BTT TCT GTG GGG BTG GCB TBC BCG TBG GCB GCT CCB BGB GCT BGC BBB CTC BBB TGC BGB BGC BTC CTC BTG GCT CTG BBB CG-3' (FRAG NO 1148)

(SEQ DD NO 10526) Human IL-5 Receptor Nucleic Acid and Antisense Oligonucleotide Fragments

5'-CTCAGTGGCC CCCAAAAGGA TGAGTAATAC ATGCGCCACG ATGATCATAT CCTTTTTACT ATGAGGCCGT GTCTGTCGTG TCTTTCCTTT GCTCTTGGTG TGTCTTTGCT

GTGCCCTGCC TCTCTGCCCG TGTCTGTCGT GTCTTTCCTT TGCTCTTGGT GTGTCTTTGC TGTGCCCTGC CTCTCTGCC CGTGTCTGTC GTGTCTTTCC TTTGCTCTTG

GTGTGTCTTT GCTGTGCCCT GCCTCTCTGC-3' (FRAG NO 1765) (SEQ DD NO 11147)

5'-CCG TGT C-3' (FRAG NO 1766) (SEQ ID NO 11148) 5'-GQCCTGCC-3' (FRAG NO 1767) (SEQ DD NO 11149)

5'-CCG TGT CTG TCG TGT CT-3' (FRAG NO 1149) (SEQ ID NO 10527)

5'-TTCCTTTGCTCTTG-3' (FRAG NO 1150) (SEQ ID NO 10528)

5'-GTGTGTCTTTGCTGT-3' (FRAG NO 1151) (SEQ ID NO 10529)

5'-GCCCTGCCTCTCTGC-3' (FRAG NO 1152) (SEQ ID NO 10530) 5'-CT CBGTGGCCCC CBBBBGGBTG BGTBBTBCBT GCGCCBCGBT GBTCBTBTCC TTTTTBCTBT GBGG (FRAG NO 1768) (SEQ ID NO 11150)

Human IL-6 Receptor Fragments

5'-GGGGGTGGCT TCCTGCCGCG TCTCTGGGCC GTCCCGTCCC TCGGCCCCGC GCCGCGCTCG GCTCCTCTCC CTCTGGCCCG GCTCGGGGCG GGGCGGGGCG

GTGGGCGGGC GGCGCTGCCC TGCGCGCGGC GCTGGCCCCT GCTGGCCGTC GGCTGCGCGC TGCTGGCTGC CCTGCTGGCC GCGCCGGGGC CTGTCCGCCT CTGCGGGCGC

TGTCTCCTGG CTTGTCTTCC GGCTCTTCTG CTGGGGTGGG GCTGGGCGGC CGGCCCGGTG CTGGGGCTCC TCGGGGGGGG GGGCTCTTCC GGGCTGTCTC CCTCCGGGGC GGGGGTTTCT GGCCGTGGGG GTCTTGCCTG GCCTCCGGGC TCCTGCTTGT CTTGCCTTCC TTCTCTGGTC GGTTGTGGCT CGGGGCTCCG TGGGTCCCTG GCGCCCGTTT

GTGTTTTGTC TTTTCCCCTG GCGTCCCTGT GCCCCTCTCC TCTCCTTCCT CTGCTTCTCG CTCTCCTTTG TGGGGCCCTC CCTGCTGCTC TTGGTTTTGG GCTTTTTTTC

TCTTCCTCCT TTTTCGTGCG TGGGCCTCCG CACGCCTCTT GCCACCTCCT GCGCAGGGCA GCGCCTTGG GGCCAGCGCC GCTCCCGGCG CGGCCAGCAG GGCAGCCAGC

AGCGCGCAGC CGACGGCCAG CATGCTTCCT CCTCGGCTAC CACTGCATGG TCCCGCAGAG GCGGACAGGC GCBCGCCTC TTGCCBCCTC CTGCGCBGGG CBGCGCCTTG

GGGCCBGCGC CGCTCCCGGC GCGGCCBGCB GGGCBGCCBG CBGCGCGCBG CCGBCGGCCB GCBTGCTTCC TCCTCGGCTB CCBCTCCBTG GTCCCGCBGB GGCGGBCBGG C-3' (FRAG NO 1769) (SEQ DD NO 11151)

5'-CCCGGCGC-3' (FRAG NO 1184) (SEQ ID NO 10562)

5'-GGCCBGCBGG-3' (FRAG NO 1186) (SEQ ID NO 10564)

5'-GCBGCCBGCBGCG-3' (FRAG NO 1770) (SEQ ID NO 11152)

5'-C GCBGCCGBCGGCC -3' (FRAG NO 1771) (SEQ ID NO 11153) 5'-GGGGGTGGCTTCCTGCC3'- (FRAG NO 1153) (SEQ ID NO 10531)

5'-GCGTCTCTGGGCCGTCCC-3' (FRAG NO 1154) (SEQ ID NO 10532)

5'-GTCCCTCGGCCCCGCGCCGCGCTCGGCTCCTCTCCC-3' (FRAG NO 1155) (SEQ DD NO 10533)

5'-TCTGGCCCGGCTC-3' (FRAG NO 1156) (SEQ ID NO 10534)

5'-GGGGCGGGGCGGGGCGGTGGGCGGGC-3' (FRAG NO 1157) (SEQ ID NO 10535) 5'-GGCGCTGCCCTGCGC-3' (FRAG NO 1158) (SEQ DD NO 10536)

5'-GCGGCGCTGGCCCC-3' (FRAG NO 1159) (SEQ ID NO 10537)

5'-TGCTGGCCGTCGGCTGCGCGCTGCTGGCTGCCCT-3' (FRAG NO 1160) (SEQ ID NO 10538)

5'-GCTGGCCGCGCCGGG 3' (FRAG NO 1161) (SEQ DD NO 10539)

5'-GCCTGTCCGCCTCTGCGGG-3' (FRAG NO 1162) (SEQ ID NO 10540) 5'-CGCTGTCTCCTGGC-3' (FRAG NO 1163) (SEQ ID NO 10541)

5'-TTGTCTTCCGGCTCT-3' (FRAG NO 1164) (SEQ D NO 10542)

5'-TCTGCTGGGGTGGG-3' (FRAG NO 1165) (SEQ ID NO 10543)

5'-GCTGGGCGGCCGGCCCGGT-3' (FRAG NO 1166) (SEQ ID NO 10544)

5'-GCTGGGGCTCCTCGGGGGG-3' (FRAG NO 1167) (SEQ D NO 10545) S'-GGGGGCTCTTCCGG-3' (FRAG NO 1168) (SEQ ID NO 10546)

5'-GCTGTCTCCCTCCGGG-3' (FRAG NO 1169) (SEQ DD NO 10547)

5' GCGGGGGTTTCTGGCC-3' (FRAG NO 1170) (SEQ DD NO 10548)

5'-GTGGGGGTCTTGCC-3' (FRAG NO 1171) (SEQ ID NO 10549) 5'-TGGCCTCCGGGCTCC-3' (FRAG NO 1172) (SEQ DD NO 10550)

5'-TGCTTGTCTTGCCTTCCTTC-3' (FRAG NO 1173) (SEQ ID NO 10551)

5'-TCTGGTCGGTTGTGGCTCG-3' (FRAG NO 1174) (SEQ D NO 10552)

5'-GGGCTCCGTGGGTCCCTGGC-3' (FRAG NO 1175) (SEQ ID NO 10553) 5'-GCCCGTTTGTGTTTTGTC-3' (FRAG NO 1176) (SEQ ID NO 10554)

5'-TTTTCCCCTGGCGT-3' (FRAG NO 1177) (SEQ DD NO 10555)

5'-CCCTGTGCCCCTCTCCTCTCCTTCCTCTGCTTCTC-3' (FRAG NO 1178) (SEQ DD NO 10556)

5'-GCTCTCCTTTGTGGG-3' (FRAG NO 1179) (SEQ DD NO 10557)

5'-GCCCTCCCTGCTGCT-3' (FRAG NO 1180) (SEQ DD NO 10558) 5'-CTTGGTTTTGGGCT-3' (FRAG NO 1181) (SEQ ED NO 10559)

5'.χχχTχχCXCTTCCTCCTTTTTC-3' (FRAG NO 1182) (SEQ ED NO 10560)

5'-GTGCGTGGGCCTCC-3' (FRAG NO 1183) (SE DD NO 10561)

5'-GCACGCCTCT TGCCACCTCC TGCGCAGGGC AGCGCCTTGG GGCCAGCGCC GCTCCCGGCG CGGCCAGCAG GGCAGCCAGC AGCGCGCAGC CGACGGCCAG

CATGCTTCCT CCTCGGCTAC CACTCCATGG TCCCGCAGAG GCGGACAGGC 3' (FRAG NO 1185) (SEQ DDNO 10563) S'-GCBCGCCTCT TGCCBCCTCC TGCGCBGGGC BGCGCCTTGG GGCCBGCGCC GCTCCCGGCG CGGCCBGCBG GGCBGCCBG CBGCGCGCBG CCGBCGGCCB GCBTGCTTCC

TCCTCGGCTB CCBCTCCBTG GTCCCGCBGB GGCGGBCBGG C-3' (FRAG NO 1187) (SEQ ID NO 10565)

Human IL-6 Nucleic Acid and Antisense Oligonucleotide Fragments

5'-GGGGGTGGCT TCCTGCCGCG TCTCTGGGCC GTCCCGTCCC TCGGCCCCGC GCCGCGCTCG GCTCCTCTCC CTCTGGCCCG GCTCGGGGCG GGGCGGGGCG

GTGGGCGGGC GGCGCTGCCC TGCGCGCGGC GCTGGCCCCT GCTGGCCGTC GGCTGCGCGC TGCTGGCTGC CCTGCTGGCC GCGCCGGGGC CTGTCCGCCT CTGCGGGCGC TGTCTCCTGG CTTGTCTTCC GGCTCTTCTG CTGGGGTGGG GCTGGGCGGC CGGCCCGGTG CTGGGGCTCC TCGGGGGGGG GGGCTCTTCC GGGCTGTCTC CCTCCGGGGC

GGGGGTTTCT GGCCGTGGGG GTCTTGCCTG GCCTCCGGGC TCCTGCTTGT CTTGCCTTCC TTCTCTGGTC GGTTGTGGCT CGGGGCTCCG TGGGTCCCTG GCGCCCGTTT

GTGTTTTGTC TTTTCCCCTG GCGTCCCTGT GCCCCTCTCC TCTCCTTCCT CTGCTTCTCG CTCTCCTTTG TGGGGCCCTC CCTGCTGCTC TTGGTTTTGG GCTTTTTTTC

TCTTCCTCCT TTTTCGTGCG TGGGCCTCC GCACGCCTCT TGCCACCTCC TGCGCAGGGC AGCGCCTTGG GGCCAGCGCC GCTCCCGGCG CGGCCAGCAG GGCAGCCAGC

AGCGCGCAGC CGACGGCCAG CATGCTTCCT CCTCGGCTAC CACTCCATGG TCCCGCAGAG GCGGACAGGC GCBCGCCTC TTGCCBCCTC CTGCGCBGGG CBGCGCCTTG GGGCCBGCGC CGCTCCCGGC GCGGCCBGCB GGGCBGCCBG CBGCGCGCBG CCGBCGGCCB GCBTGCTTCC TCCTCGGCTB CCBCTCCBTG GTCCCGCBGB GGCGGBCBGG

C-3' (FRAG NO 1772) (SEQ DD NO 11154)

5' GGGGCBGG-3' (FRAG NO 1773) (SEQ ID NO I I 155)

5'-GBBGGCBG CBGGC-3' (FRAG NO 1774) (SEQ ID NO 11156)

5'-CCBGGBGCBG CCCC-3' (FRAG NO 1775) (SEQ ID NO 11157) 5'-BGGG BGBBGGCBBC-3' (FRAG NO 1776) (SEQ DD NO 11158)

5'-GCT TCT CTT TCG TTC CCG GTG GGC TCG-3' (FRAG NO 1188) (SEQ DDNO 10566)

5'-GTG GCT GTC TGT GTG GGG CGG CT-3' (FRAG NO 1189) (SEQ DD NO 10567)

S'-GTG CCT CTT TGC TGC TTT C-3' (FRAG NO 1190) (SEQ ID NO 10568)

5'-GAT TCT TTG CCT TTT TCT GC-3' (FRAG NO 1191) (SEQ ID NO 10569) 5'-CTCCTGGGGG TBCTGGGGCB GGGBBGGCBG CBGGCBBCBC CBGGBGCBGC CCCBGGGBGB BGGCBBCTGG BCCGBBGGCG CTTGTGGBGB BGGBGTTCBT

BGCTGGGCTC CTGGBGGGGB GBTBGBGC-3'(FRAG NO 1777)(SEQ ID NO 11159)

Human Monocvte-derived Neutrophil Chemotactic Factor Nucleic Acid and Antisense Oligonucleotide Fragments

5'-GGGGTGGBBB GGTTTGGBGT BTGTCTTTBT GCBCTGBCBT CTBBGTTCTT TBGCBCTCCT TGGCBBBBCT GCBCCTTCBC BCBGBGCTGC BGBBBTCBGG BBGGCTGCCB BGBGBGCCBC GGCCBGCTTG GBBGTCBTGT TTBCBCBCBG TGBGBTGGTT CCTTCCGGGC TTGTGTGCTC TGCTGTCTCT TGGTTCCTTC CGGTGGTTTC TTCCTGGCTC

TTGTCCTTTC TCTTGG CCCT TGGC-3' (FRAG NO 1778) (SEQ DD NO 11160)

5'-GGBGT BTG-3' (FRAG NO 1779) (SEQ DD NO 11161)

5'-GCBCTGBCBT CT-3' (FRAG NO 1780) (SEQ ID NO 11162)

5'-CCG GTG G 3' (FRAG NO 1781) (SEQ ID NO 11163) 5'-GG CCC TTG GC-3' (FRAG NO 1782) (SEQ D NO 11164)

5'-GCT TGT GTG CTC TGC TGT CTC T-3' (FRAG NO 1192) (SEQ ID NO 10570)

5'-TGG TTC CTT CCG GTG GTT TCT TCC TGG CTC TTG TCC T-3' (FRAG NO 1193) (SEQ ID NO 10571)

5'-TTC TCT TGG CCC TTG GC 3' (FRAG NO 1194) (SEQ ID NO 10572)

5'-GGGGTGGBBB GGTTTGGBGT BTGTCTTTBT GCBCTGBCBT CTBBGTTCTT TBGCBCTCCT TGGCBBBBCT GCBCCTTCBC BCBGBGC3' (FRAG NO 1783) (SEQ ID NO 11165)

Human Neutrophil Elastase (Mediillasin) Nucleic Acid and Antisense Oligonucleotide Fragments

5'-GGGCTCCCGC CGCGBGBGGT TBTGGGCTCC CBGGBCCBCC CGCBCCGCGC GGBCGTTTBC BTTCGCCBCG CBGTGCGCGG CCGBCBTGBC GBBGTTGGGC

GCBBTCBGGG TGGCGCCGCB GBBGTGGCCT CCGCGCBGCT GCBGGGBCBC CBTGBBGGGC CBCGCGTGGG GCCGCGCTCG CCGGCCCCCC BCBBTCTCCG BGGCCBGCGC

GGTGCCCCCC BGCBGCBBGG CCGGCBGGBC BCBGGCGBGG BGBCBCGCGB GTCGGCGGCC GBGGGTCBTG GTGGGGCTGG GGCTCCGGGG TCTCTGCCCC TCCGTGCTGG TGGGGCTGGG GCTCCGGGG TCTCTGCCCC TCCGTGCCGC GTGGGGCCGC GCTCGCCGGC CCCCCCCTGC CGGGTGGGCT CCCGCCGCGC GCCGGCCTGC CGGCCCCTCG

TGGGTCCTGC TGGCCGGGTC CGGGTCCCGG GGGTGGGGCG CGBGTCGGCGGCCGBGGGTC-3' (FRAG NO 1784) (SEQ ID NO 11166)

5'-GG TGG GGC-3' (FRAG NO 1785) (SEQ ID NO 11167)

5'-G GGG CCG -3' (FRAG NO 1786) (SEQ ID NO 11168)

5'- GGC CGG GTC CGG G-3' (FRAG NO 1787) (SEQ ID NO 11169) 5'-TGG TGG GGC TGG GGC TCC GGG GTC TCT GCC CCT CCG TGC-3' (FRAGNO 1195)(SEQ DD NO 10573)

S'-CGC GTG GGG CCG CGC TCG CCG GCC CCC C-3^» (FRAG NO 1196) (SEQ DD NO 10574)

S'-CCT GCC GGG TGG GCT CCC GCC GCG-3' (FRAG NO 1197) (SEQ D NO 10575)

5'-CGC CGG CCT GCC GGC CCC TC-3' (FRAG NO 1198) (SEQ ID NO 10576)

5'-GTG GGT CCT GCT GGC CGG GTC CGG GTC CCG GGG GTG GGG-3'(FRAGNO 1199)(SEQ ID NO 10577) 5'-CGC GBG TCG GCG GCC GBG GGT C-3' (FRAG NO 1200) (SEQ ID NO 10578)

5'-GGGCTCCCGC CGCGBGBGGT TBTGGGCTCC CBGGBCCBCC CGCBCCGCGC GGBCGTTTBC BTTCGCCBCG CBGTGCGCGG CCGBCBTGBC GBBGTTGGGC

GCBBTCBGGG TGGCGCCGCB GBBGTGGCCT CCGCGCBGCT GCBGGGBCBC CBTGBBGGGC CBCGCGTGGG GCCGCGCTCG CCGGCCCCCC BCBBTCTCCG BGGCCBGCGC

GGTGCCCCCC BGCBGCBBGG CCGGCBGGBC BCBGGCGBGG BGBCBCGCGB GTCGGCGGCC GBGGGTCBTG GTGGGGCTGG GGCTCCGGGG TCTCTGCCCC TCCGTGC-3'

(FRAG NO 1788) (SEQ DD NO 11170) Human Neutrophil Oxidase Factor Nucleic Acid and Antisense Oligonucleotide Fragments

5'-CGGGBGTGGG GGTCCTGGBC GGCBCTGBBG GCBTCCBGGG CTCCCTTCCB GTCCTTCTTG TCCGCTGCCB GCBCCCCTTC BTTCCBGBGG CTGBTGGCCT CCBCCBGGGB

CBTGBTTBGG TBGBBBCTBG GBGGCCGGCC TCCBCCBGGG BCBTGGTCCT TCTTGTCCGC TGCCTCTCTG GGGTTTTCGG TCTGGGTGGG CTTTCCTCCT GGGGCTGCTG

CTGGGCTCTT CTTTTTGTTT CTGGCCTGGT GCTCTCTCGT GCCCTTTCCC TTGGGTGTCT TGTTTTTGTG GCCTCCBCCB GGGBCBTG-3' (FRAG NO 1789) (SEQ DD

NO 11171) 5'-CGGGBGTGGG GG-3 ' (FRAG NO 1790) (SEQ ID NO 11172)

5'-GCCBGCBCCCC-3' (FRAGNO 1791) (SEQ D NO 11173)

5'-C CBC CBG-3' (FRAG NO 1792) (SEQ ID NO 11174)

5'-GGC CTC CBC CBG GGB CBT G-3' (FRAG NO 1201) (SEQ DD NO 10579)

5'-GTC CTT CTT GTC CGC TGC C -3' (FRAG NO 1202) (SEQ ID NO 10580) 5'-TCT CTG GGG TTT TCG GTC TGG GTG G-3 (FRAG NO 1203) (SEQ D NO 10581)

5'-GCT TTC CTC CTG GGG CTG CTG CTG-3' (FRAG NO 1204) (SEQ ID NO 10582)

5'-GGC TCT TCT TTT TGT TTC TGG CCT GGT G-3' (FRAG NO 1205) (SEQ ID NO 10583)

5'-CTC TCT CGT GCC CTT TCC-3' (FRAG NO 1206) (SEQ ID NO 10584)

5'-CTT GGG TGT CTT GTT TTT GT-3' (FRAG NO 1207) (SEQ DD NO 1216 5'-GGC CTC CBC CBG GGB CBT G-3' (FRAG NO 1208) (SEQ ID NO 10586)

5'-CGGGBGTGGG GGTCCTGGBC GGCBCTGBBG GCBTCCBGGG CTCCCTTCCB GTCCTTCTTG TCCGCTGCCB GCBCCCCTTC BTTCCBGBGG CTGBTGGCCT CCBCCBGGGB

CBTGBTTBGG TBGBBBCTBG GBGGCC-3' (FRAG NO 1793) (SEQ ID NO 11175)

Human Cathensin G Nucleic Acid and Antisense Oligonucleotide Fragments

5'-CCCTCCBCBT CTGCTCTGBC CTGCTGGBCT CTGGBTCTGB BGBTBCGCCB TGTBGGGGCG GGBGTGGGGC CTGCTCTCCC GGCCTCCGBT GBTCTCCCCT GCCTCBGCCC CBGTGGGTBG GBGBBBGGCC BGCBGBBGCB GGBGTGGCTG CBTCTTTCCT GGTGGGGCCT GCTCTCCCGG CCTCCGTGTG TTGCTGGGTG TTTTCCCGTC TCTGGTCTGC

CTTCGGGGGT CGT-3' (FRAG NO 1794) (SEQ D NO 11176)

5'-GBBGBTBCGCC-3' (FRAG NO 1795) (SEQ ID NO 11177)

5'-CBGCCCCBG-3' (FRAG NO 1796) (SEQ ED NO 11178)

5'-TCC CGT CTC TGG-3' (FRAG NO 1797) (SEQ DD NO 11179) 5'-GTG GGG CCT GCT CTC CCG GCC TCC G-3' (FRAG NO 1209) (SEQ DDNO 10587)

5'-TGT GTT GCT GG GTG TTT TCC CGT CTC TGG-3' (FRAG NO 1210) (SEQ DDNO 10588)

5'-TCT GCC TTC GGG GGT CGT-3' (FRAG NO 1211) (SEQ DD NO 10589) 5'-CCCTCCBCBT CTGCTCTGBC CTGCTGGBCT CTGGBTCTGB BGBTBCGCCB TGTBGGGGCG GGBGTGGGGC CTGCTCTCCC GGCCTCCGBT GBTCTCCCCT GCCTCBGCCC CBGTGGGTBG GBGBBBGGCC BGCBGBBGCB GGBGTGGCTG-3' (FRAG NO 1798) (SEQ ID NO 11180)

Human Defensin 1 Nucleic Acid and Antisense Oligonucleotide Fragments

5'-CCGGGGCTGC BGCBBCCTCB TCBGCTCTTG CCTGGBGTGG CTCBGCCTGG GCCTGCBGGG CCBCCBGGBG BBTGGCBGCB BGGBTGGCGB GGGTCCTCBT GGCTGGGGTC BCBGBTCCTC TBGCTBGGCB GGGTGBCCBG BGBGGGC GGG TCC TCB TGG CTG GGG GCC TGG GCC TGC BGG GCC GCT CTT GCC TGG BGT GGC TC

GCC CBG BGT CTT CCC TGG T GCTCAGCGTC CAAAGGAGCC AGCCTCTCCC CAGTTCCTGA AATCCTGAGT GTTGCCTGCC AGTCGCCATG AGAACTTCCT ACCTTCTGCT GTTTACTCTC TGCTTACTTT TGTCTGAGAT GGCCTCAGGT GGTAACTTTC TCACAGGCCT TGGCCACAGA TCTGATCATT ACAATTGCGT CAGCAGTGGA GGGCAATGTC TCTATTCTGC CTGCCCGATC TTTACCAAAA TTCAAGGCAC CTGTTACAGA GGGAAGGCCA AGTGCTGCAA GTGAGCTGGG AGTGACCAGA AGAAATGACG CAGAAGTGAA ATGAACTTTT TATAAGCATT CTTTTAATAA AGGAAAATTG CTTTTGAAGT AT CTGCAGTGGT AAAAAGATTC TATATCTGCT GTTTGATGAA TGCAGCACCC ACTAGCCACA TAGTGCTCGT GAGCACTTGC AATGCGGCTA GGGTGATTTC AATTAACCTA AAAGAGAACA GCCACAGGGA GCATGTGGCT GCCATATTGG ATGGTGCTGC

TTTGAGAACA AAATGAGAGA AATGAAGCCT CTATTTACCT TGGTTGGCGG AACACATTGA AGGGACTCTG TATTGATACC AGGCTTCAAA CTTTGGGAAG TGTACTGGCC AACTTAAACA CATCCACAGG AGAATGAAGA GGTTTGGGAA GGGACCAGAA ACCAGGCATT GAGGACAATG AGAAGAGTTT TTCAAAAGTG GAATTACTGC AAAAAGTGGA AAAATAGCCT TTGGATGGAA GTTACTGATG AGACAATTTC CATCGGTGTG AAAGCCATCT TTCCAACAGA GATCTGCAAC ATGAGAATGT ACTGTCTCCT AGGGTAGCGA TGGCCTCTTG TATTAGTCCG CTCAGGCTAC CAGATTTATC GTTTAAACTG CCCATAAACA GACCAGGCAG TTTAAACAAC AGAAATTTAT TTCCTCGCAG TCCTGGAGGC AGGAAGTCTG CGATCAAGGT GGAAGCAGGG TTGGCTTCTT CTCAGGTGTC TGTCCTTGGC TGGTAGATGA CCGCCGCCTC CCTGGGTCCT CACATGGTCT

TTCCTCTGTG TGTGTCTGTC CCAATCTCTT CTTATAAGGA TGCAAGTCTT ATGGATCAGA GCACACCCCA ATGACCGTGT TTAACTTGAA TCACCTCTTT AAAGTTTCTC TCTCCAAATA CAATCACCTC CTGAGGCACT GTTAGGGCTT CGACACAGGA ATTCTTTTCC TAGGGGATTC AGTTCAGTCC AAAACGCCTA CCAGTGGAGA CTTGCAACAT GGCGGCCTGC TGGTCCCTCG CCAGGAATAT CACAGGCGAC TGTTCCCTGT TGCATGGAAT AGAAGGCTAT TCCAGAGTAC TGTCTCTATT TATCAGATCT GGGATACTGG GAGAAGGGCA AAATAAAGTC CAAGTAGAAA AAAAAACTAT GAAAGTTTTA GAGAGTAACC ATAATTTCAG CCCGATGTGA AACGATCCTA GATTTCAGCT GAAATAGTGA TGTGGGAAGT GAGGGGGCCG GGATTCAAGG CAGAGGGAAC AGCGTAACTG AAGGCATGGA AGGAGGGAAG TGTAGGCTGT GTTTGAAGAG TGGCAGCTGC

TTCCACATTT CTAAAACACA GGATGTGATT TTGGGGTGTG TTGAGACAAG GCAGAAAACT TGTTTGGAAA AATAACTTGA ATTCCCTGCA CATTTAAAAT CTCTCAGCAG AAGAAAACCC CACTCAGAAC CCCACTGTTC ATTCCTTGGC TTGTATTTGG SCACAGCTGG CATAGCCCCA GACTGAGTAA GCTCTTCAGA CACCTCATTT CATGAGTAGC CCCAAAGATC AATCATGGGC CAATTTCTTG GAAGAGAAGA CTCTCCGGTG TTTTGCAGTT ATTTGTTCTG CTTTCGCGAG ATGTTCTCAA ATCGTTGCAG CTACAAGCCA TGAGTCTGAA GTGTTTGTGT TCCCTCCTTA CAGGTGGTAA CTTTCTCACA GGCCTTGGCC ACAGATCTGA TCATTACAAT TGCGTCAGCA GTGGAGGGCA ATGTCTCTAT TCTGCCTGCC CGATCTTTAC CAAAATTCAA GGCACCTGTT ACAGAGGGAA GGCCAAGTGC TGCAAGTGAG CTGAGAGTGA CCAGAAGAAA TGACGCAGAA

GTGAAATGAA CTTTTTATAA GCATTCTTTT AATAAAGGAA AATTGCTTTT GAAGTATACC TCCTTTGGGC CAAAATGAAT CTTGTGTCTC AATTGGAAGA GGTAAAGAAG TAGGGGGTTA GGGTGCATGG GTTGGAACGT GAGACAGGTC GAACCACAAA GCCTGCCTGG AAAAGGGGAG TGACGTCCTA GGCTTCAGTG ATGTCACCTC CACTTTGTTT GATCCACAAA CCAACAGGTG ACTGATTTTG GTCAGCTCAG CCTCCAAAGG AGCCAGCCTC TCCCCAGTTC CTGAAATCCT GAGTGTTGCC TGCCAGTCGC CATGAGAACT TCCTACCTTC TGCTGTTTAC TCTCTGCTTA CTTTTGTCTG AGATGGCCTC AGGTGGTAAC TTTCTCACAG GCCTTGGCCA CAGATCTGAT CATTACAATT GCGTCAGCAG TGGAGGGCAA TGTCTCTATT CTGCCTGCCC GATCTTTACC AAAATTCAAG GCACCTGTTA CAGAGGGAAG GCCAAGTGCT GCAAGTGAGC TGGGAGTGAC CAGAAGAAAT

GACGCAGAAG TGAAATGAAC TT -3' (FRAG NO 1799) (SEQ ID NO 12379)

5'-GTCAGCTCAG CCTCCAAAGG AGCCAGCCTC TCCCCAGTTC CTGAAATCCT GAGTGTTGCC TGCCAGTCGC CATGAGAACT TCCTACCTTC TGCTGTTTAC TCTCTGCTTA CTTTTGTCTG AGATGGCCTC AGGTGGTAAC TTTCTCACAG GCCTTGGCCA CAGATCTGAT CATTACAATT GCGTCAGCAG TGGAGGGCAA TGTCTCTATT CTGCCTGCCC GATCTTTACC AAAATTCAAG GCACCTGTTA CAGAGGGAAG GCCAAGTGCT GCAAGTGAGC TGGGAGTGAC CAGAAGAAAT GACGCAGAAG TGAAATGAAC TT-3' (FRAGNO ) (SEQ ID NO 11844)

5'-CTGCAGTGGT AAAAAGATTC TATATCTGCT GTTTGATGAA TGCAGCACCC ACTAGCCACA TAGTGCTCGT GAGCACTTGC AATGCGGCTA GGGTGATTTC AATTAACCTA AAAGAGAACA GCCACAGGGA GCATGTGGCT GCCATATTGG ATGGTGCTGC TTTGAGAACA AAATGAGAGA AATGAAGCCT CTATTTACCT TGGTTGGCGG AACACATTGA AGGGACTCTG TATTGATACC AGGCTTCAAA CTTTGGGAAG TGTACTGGCC AACTTAAACA CATCCACAGG AGAATGAAGA GGTTTGGGAA GGGACCAGAA ACCAGGCATT GAGGACAATG AGAAGAGTTT TTCAAAAGTG GAATTACTGC AAAAAGTGGA AAAATAGCCT TTGGATGGAA GTTACTGATG AGACAATTTC CATCGGTGTG AAAGCCATCT TTCCAACAGA GATCTGCAAC ATGAGAATGT ACTGTCTCCT AGGGTAGCGA TGGCCTCTTG TATTAGTCCG CTCAGGCTAC CAGATTTATC GTTTAAACTG

CCCATAAACA GACCAGGCAG TTTAAACAAC AGAAATTTAT TTCCTCGCAG TCCTGGAGGC AGGAAGTCTG CGATCAAGGT GGAAGCAGGG TTGGCTTCTT CTCAGGTGTC TGTCCTTGGC TGGTAGATGA CCGCCGCCTC CCTGGGTCCT CACATGGTCT TTCCTCTGTG TGTGTCTGTC CCAATCTCTT CTTATAAGGA TGCAAGTCTT ATGGATCAGA GCACACCCCA ATGACCGTGT TTAACTTGAA TCACCTCTTT AAAGTTTCTC TCTCCAAATA CAATCACCTC CTGAGGCACT GTTAGGGCTT CGACACAGGA ATTCTTTTCC TAGGGGATTC AGTTCAGTCC AAAACGCCTA CCAGTGGAGA CTTGCAACAT GGCGGCCTGC TGGTCCCTCG CCAGGAATAT CACAGGCGAC TGTTCCCTGT TGCATGGAAT AGAAGGCTAT TCCAGAGTAC TGTCTCTATT TATCAGATCT GGGATACTGG GAGAAGGGCA AAATAAAGTC CAAGTAGAAA AAAAAACTAT GAAAGTTTTA GAGAGTAACC

ATAATTTCAG CCCGATGTGA AACGATCCTA GATTTCAGCT GAAATAGTGA TGTGGGAAGT GAGGGGGCCG GGATTCAAGG CAGAGGGAAC AGCGTAACTG AAGGCATGGA AGGAGGGAAG TGTAGGCTGT GTTTGAAGAG TGGCAGCTGC TTCCACATTT CTAAAACACA GGATGTGATT TTGGGGTGTG TTGAGACAAG GCAGAAAACT TGTTTGGAAA AATAACTTGA ATTCCCTGCA CATTTAAAAT CTCTCAGCAG AAGAAAACCC CACTCAGAAC CCCACTGTTC ATTCCTTGGC TTGTATTTGG SCACAGCTGG CATAGCCCCA GACTGAGTAA GCTCTTCAGA CACCTCATTT CATGAGTAGC CCCAAAGATC AATCATGGGC CAATTTCTTG GAAGAGAAGA CTCTCCGGTG TTTTGCAGTT ATTTGTTCTG CTTTCGCGAG ATGTTCTCAA ATCGTTGCAG CTACAAGCCA TGAGTCTGAA GTGTTTGTGT TCCCTCCTTA CAGGTGGTAA CTTTCTCACA GGCCTTGGCC ACAGATCTGA TCATTACAAT TGCGTCAGCA GTGGAGGGCA ATGTCTCTAT TCTGCCTGCC CGATCTTTAC CAAAATTCAA GGCACCTGTT ACAGAGGGAA GGCCAAGTGC TGCAAGTGAG CTGAGAGTGA CCAGAAGAAA TGACGCAGAA GTGAAATGAA CTTTTTATAA GCATTCTTTT AATAAAGGAA AATTGCTTTT GAAGTATACC TCCTTTGGGC CAAAATGAAT CTTGTGTCTC AATTGGAAGA GGTAAAGAAG TAGGGGGTTA GGGTGCATGG GTTGGAACGT GAGACAGGTC GAACCACAAA GCCTGCCTGG AAAAGGGGAG TGACGTCCTA GGCTTCAGTG ATGTCACCTC CACTTTGTTT GATCCACAAA CCAACAGGTG ACTGATTTTG-3' (FRAG NO ) (SEQ DD NO 11843) 5'-GCTCAGCCTC CAAAGGAGCC AGCCTCTCCC CAGTTCCTGA AATCCTGAGT GTTGCCTGCC AGTCGCCATG AGAACTTCCT ACCTTCTGCT GTTTACTCTC TGCTTACTTT

TGTCTGAGAT GGCCTCAGGT GGTAACTTTC TCACAGGCCT TGGCCACAGA TCTGATCATT ACAATTGCGT CAGCAGTGGA GGGCAATGTC TCTATTCTGC CTGCCCGATC TTTACCAAAA TTCAAGGCAC CTGTTACAGA GGGAAGGCCA AGTGCTGCAA GTGAGCTGGG AGTGACCAGA AGAAATGACG CAGAAGTGAA ATGAACTTTT TATAAGCATT

CTTTTAATAA AGGAAAATTG CTTTTGAAGT AT-3' (FRAG NO ) (SEQ ID NO 11841)

5'-CCGGGGC-3' (FRAG NO 1800) (SEQ DD NO 11182) 5'-GG GCCTGCBGGG CC-3' (FRAG NO 1801) (SEQ ID NO 11183)

5'-GGCBGCB BGG-3' (FRAG NO 1802) (SEQ ID NO 11184) 5'-GGG TCC TCB TGG CTG GGG-3' (FRAG NO 1212) (SEQ ID NO 10590) 5'-GCC TGG GCC TGC BGG GCC-3' (FRAG NO 1213) (SEQ ID NO 10591) 5'-GCT CTT GCC TGG BGT GGC TC-3' (FRAG NO 1214) (SEQ DD NO 10592) 5'-GCC CBG BGT CTT CCC TGG T-3' (FRAG NO 1215) (SEQ ID NO 10593)

5'-CCGGGGCTGC BGCBBCCTCB TCBGCTCTTG CCTGGBGTGG CTCBGCCTGG GCCTGCBGGG CCBCCBGGBG BBTGGCBGCB BGGBTGGCGB GGGTCCTCBT GGCTGGGGTC BCBGBTCCTC TBGCTBGGCB GGGTGBCCBG BGBGGGC-3' (FRAG NO 1803) (SEQ ID NO 11185)

Human Defensin 2 Nucelic Acid and Antisense Oligonucleotide Fragments

5'-ATCCTTTAAG TCAATGGACT TTGCATCAGT CACACCATCT TTTGTTACTT TGGACTTCCC CAGCTATGTT CAATAATTAC TGTTCTTCCC TTGGGCCCCA TTGTAATGGC TACAGCCTCG ACAAAAAGTC TACACTTTGA AGCATTAAGG CTCGGACATC AGCACCAAAT TTTACATCTT TACCATCACT TCAAGTGAGG TGAGGAGCCA GTAGCCTGGA

CACTGGTCTC ATCTGGTGAA AGACTGTGGG TAATGGAAGC ATTTCTGTGG GGTGCTGGCA GGACATGTGC ATGGCGAGGC AGGTCATCAG CAGCAAGTGA GAGCTGCCTC TTACTTTCTA AAGGTGACAT AGCAAATATA CAAAAAAAAA TAAATAAATT ATTAATTTAG GTAGAGCACA TAAAGGCTTT ATTTCATATT CCATTTCTCT GTATGCTTTC TTCACCAGGA AGAAATAGTT TTAGTGTCAG GAATGAATGA GTCTGCCCCT CAATTCCAGC CTGCTCAACA CACAAGGAAA CAAAGCCCTG ACAATCAGAG TGACTCCCTG GTGACTAAGC TCCCAGTCCT GGATGCATAT TTGTTTAGCA GTTCTGACAG CATTTGACCC AGCCCTCTCT CTGCATATCC CATCAGAACC TTCTTTTTTT TTTTTTTCTT TGAGACTGAG TCTTGCTCTG TCGGAAGCGA CTCCTGTGCC TCAGCCTCCC AAATACCTGG AATTATAGGC GTAAGCCATC ATGCCTGGCT AATTTTTGTA TTTTTCATGG

AGATGGGGTT TTGCCATGTT GGTCAAATTG GTCTCACACT CCTGACCTCA TGTGATCCAC CTGCCTCAGC CTCCCAAACT GCTGGGATGA CAGGTGTAAG CCACCATGCT AGGCTCAGAA ATTTCCTTTT ATAAAAATGT CATTAAGGAT CTTGGCTGCA CAATATCGTT ACCAGCTTCC TTTAAATCCA CTTCTGGCCT GCCAGGAATC AGGTTCTTCA GAACCTGACA TTTTAAATGA AGAGGTCAGG CAGTTCATGA GGAAAGCCTC ATTGTCCCCA TGTCTCTGTC ACTGCTGCAC CCCTGAGACA TCACAGACAT GGACACTGGG GCCTGCTTGT TTCTCAAACT GCCCTTAGAT CGAAAGAGGG AGGAACCAGG ATGAATGCCA CTCATTTTCC CAAGAAAGGC CCTCTCCTGA GTGCCCGGGA TGGGGCTCTG TCCATTGCCT GGGGCCGCCA ATTGCTACTC TGGGTTACGG AGGAAGGACA GGGTCCTGAG AGACACCAGA GACCTCACAC AGCCCTGAAA ACATGGGGCT CCTTCATAAG

TGTTTCCCAT CACCAACAGG GAGACCACGT GGAGGCCTTG CAGCCCCACT CGGTGCTTCT CCACCAAATC CCAAGGGCAG TGACGCTGAC GTCTGTGGAA AGCAGAGAAA GCCCTGGCTC CCAAAGCCCT GAAGTCCCTG TGGAGCTGAC ATTCCCTGAG TGACGGTGTG AATGGAAGGA ACTCAAGTGC GGGTGGTAGG CCACCTCCTG GCCCAGGCCT GGGTGAACTC TGAGGGGACA CATGTAGTCA CAATCCCATC CTCCCATTCT CCTTCTCAGA GGAAGGAAGT GGGCATCCAT CTGCCTCATC TCTCTCCCGT GGGGAAGATG GGGAGTTTCA GGGGAACTTT CACATAAATT TCACCAGCTC AGATCTCCTG TGAGGATGGG GCCCACCATG CTCCCGGTGC TGCCAGAGGC CCTGAGCCCC TCCCAGGGTC CCTGGGTTTG AGCCAGCCCT GTATCATCCC CAGGAGCTGA ATGTCAGAGC AATGGATAGA ATTAGATGGA AAGAGCTCTC AATTTGACCT GAGACTGTCC CCAGATACTC

AGGAAAAACA GGACGTCGCA CAGAGTGGGC AGCAGGTGAG TGGCAGGTTA TAGGTCCTGA GTTTGAGTTT GTTCTCACGT GAGACAGACC CAGCCCCTCA CTCCATTCAC ACACTGGGTT TTAAATGGTG CAAGATAGGA GCAATTTTCT GGTCCCAAGA GCAGGAGGAA GGGATTTTCT GGGGTTTCCT GAGTCCAGAT TTGCATAAGA TCTCCTGAGT GTGCATTGTT CTTTGAGGAC CATTCTCTGA CTCACCAGGT AAGTGGCTGA ATTCTAACCT CTGTAATGAG CATTGCACCC AATACCAGTT CTGAACTCTA CCTGGTGACC AGGGACCAGG ACCTTTATAA GGTGGAAGGC TTGATGTCCT CCCCAGACTC AGCTCCTGGT GAAGCTCCCA GCCATCAGCC ATGAGGGTCT TGTATCTCCT CTTCTCGTTC CTCTTCATAT TCCTGATGCC TCTTCCAGGT GAGATGGGCC AGGGAAATAG GAGGGTTGGC CAAATGGAAG AATGGCGTAG AAGTTCTCTG TCTCCTCTCA TTCCCCTCCA

CCTATCTCTC CCTCATCCCT CTCTCTCCTT CCTCTCTCTG TGTGTCCCCT CCATCCTTTT CTCCTGCTTC TCTCTCTTCT TCCCTCTCTC TCTTTTTTCT GTCTTTCTTT TTCCTCTCTC CCTAGAGCAT GTCTTTCTTT CTTTCTCTTT CCTTTCTTCT ACCCACACTT TTAGACTGAA TGCCCTATTT AATTGAACAA AGCATTGCTT CCTTCAATAG AAAAGGAGTT TGAGAACCCA ATGGACACCT CACTCGTTCT TCTAAGCCAA TATGAAGGAG CCCAGTAGCT TGTAAATATC ATCTCTTCAC TGCTTTCCAT GCTACAACTG CTGAGACTAT GGTTGAAACC TGTTAGGTGA CTTTTTAAAT AAAAGGCAGA AATTTTGATT TTATCTAAAG AAAGTAGTAT AGAATGTCAT TTTCTAAATT TTTATATTTA AAGGGTAGAT ACTGCAACCT AGAGAATTCC AGATAATCTT AAGGCCCAGC CTATACTGTG AGAACTACTG CAGCAAGACA CTCTGCCTCC AGGACTTTTC TGATCAGAGG

CCCTGAGAAC AGTCCCTGCC ACTAGGCCAC TGCAGGTTCA CAGGACAGGG TACAGCCCAT TGAAACCTAC TTTTAAACCT GGATGCCTAA CCTTCATTTT CTCCTTGATA TTATGAAAAT AAAATAAAAA CCATGAAAGG ATAAAAGAGG GAGAGTGGAA GGGAAGGATG GAGAAAGGGA AAAAGAAAAT TTGAGAGTAA ATCCTAAAAC AATTAATCTA ATAGATATCA TCTTGTGAAA TCCTCATTTT ACCAATCTTA TTTATGAGTC CTGGGTTTTG TGAGAACAAT GGGGTTCTGA GAGGCACCAG AGACCTCATG TTTTCCAAAA CCTAGAACAG TATAATGAAG GAAGGCGGGG AGGCAGGGAG GCAGGGAGGC AGGGAGGCAG GGAGGCGGGC AGGTGGGGAG GGAGGGACGG AAGGAGGGAG GGAGGGAGGG AGGGAGGGAG GGAGGGATAA AAAAAGAAGA ATGAGGTTGA AACCAGGACT TAGATATTAG AAACAAGCCA TTACAAAATT TATTTCTATG GTTAATTGTG GTTTTCAACT GTAAGTTACT TGGTGTTAAT TTCCTATTAA ACAATTTCAG TAAGTTGCAT CTTTTTATCC CATCTCAGGT CAAATACTTA ACAGACTAAA TGATTTGAAA AAGCAAAAGT TTACTGGCTT GTGTGTGTTA AAATGGAGGT ATGGTGGCTT TGATATTATC TTCTTGTGGT GGAGCTGAAT TCACAAGAGA TCGTTGCTGA GCTCCTACCA GACCCCACCT GGAGGCCCCA GTCACTCAGG AGAGATCAGG GTCTTTCACA ATCAGGTTCT ACAAAAATAA ACATCCCCCC AACCACAGCA GTGCCAGTTT CCATGTCAGA AACTTAGATC CAAATGACTG ACTCGCGTCT CATTATCATG ATGGAAAAGC CCAGGCTTGA GAAAGAAGCC CGCTGCGGAT TTACTCAAGG

CGATACTGAC ACAGGGTTTG TGTTTTTCCA ACATGAGTTT TGAGTTCTTA CACGCTGTTT GCTCTTTTTG TGTGTTTTTT CCCTGTTAGG TGTTTTTGGT GGTATAGGCG ATCCTGTTAC CTGCCTTAAG AGTGGAGCCA TATGTCATCC AGTCTTTTGC CCTAGAAGGT ATAAACAAAT TGGCACCTGT GGTCTCCCTG GAACAAAATG CTGCAAAAAG CCATGAGGAG GCCAAGAAGC TGCTGTGGCT GATGCGGATT CAGAAAGGGC TCCCTCATCA GAGACGTGCG ACATGTAAAC CAAATTAAAC TATGGTGTCC AAAGATACGC AATCTTTATC CTAGTAATTG TGGTCATTGG GTGATGTTGG TTTGGGCAGG CCATCTCTAA TATCCTTGAA ACACCTTTTT CTGCTCTCCA GGAAGGGGTC AGGGCTGCCA CAGCGGGGCT TGGAGTGCTT TCCAGGGTCA CAGGCATCTG TATTCTTTGG ATTCCTTGAC CTTCCCCATT TATTCCCGGC ATTTTCCTAA AACGTGTGCT TTGCTCCTCC

TGCATCCTCC CCTTGCATGC CCTCACCTAC CCCACATCTT CCCTAAAAAA AGCAAGCCCA ACTCAAAGAC CAGTTCCCTC ATGGAATCAT AGTGGATCTG CCAAGGGAGG GGATGCCCAG TCCTCTGTTC TTCACAAGAC TCCCTTCTTC TGGCTAAGGT TTCTTATGCA ATTAT GAATTCACAT TTCTCACCTT TTGATGTATT AAGAAAGTAT GGAGAAATAT ATCCTCTATC AAATTTTCAT GCCTTCAATA ATTTCTAATT CATCAGTCAG TGTTTTTCCA TCCTTTACTG TGATGATGCC CTTTCTTCCA AACTTTTTCA TTGCATCAGA GATGATGTTA CCAATTTCTT TGTCTCCATT TGCAGAAATT GTAGCAACCT GTGCAATTTC TTCAGGTTTG GTCACAGGTT TAGACTGCTT TTTAAGTTCA GCAATTACAG CATCAACAGC TAACATCACA CCTCTCTTGA TTTCCACTGG ATTAGCACCT TTGCTAACCT TCTGGAAGGC TTATTTGGAA ATAGAGCATA CCAGTACAGC

AGCAGTGATA GTGCCATCCC CCAGTCTCTC CATTTGTGTT ATTGGCAACA TCTTGGACAA GTTTAGCTCC AATGCTTTTA TATTTATCCT TTAAGTCAAT TGACTTTGCA TCAGTCACAC CATCTTTTGT TACTTTGGGA CTTCCCCAGC TATGTTCAAT AATTACTGTT CTTCCCTTTG GCCCCATTGT AATGGCTACA GCATCGACAA AAAGTCTACA CTTTGAAGCA TTAAGGCTCA GACATCAGCA CCAAATTTTA CATCTTTACC ATCACTTCAA GTGAGGTGAG GAGCCAGTAG CCTGGACACT GGTCTCATCT GGTGAAAGAC TGTGGGTAAT GGAAGCATTT CTGTGGGGTG GTGGCAGGAC ATGTGCATGG TGAGGCAGGT CATCAGCAGC AAGTGAGAGC TGCCTCTTAC TTTCTAAAGG TGACATAGCA AGTATACAAA AAAAAATAAA ATATTAATTT AGGCAGAGCA CATAAAGGCT TTATTTCATA TTCCATTTCT CTGTATGCTT TCTTCACCAG GAAGAAATAG TTTTAGTGTC

AGGAATGAAT GAGTCTGCCC CTCAATTCCA GCCTGCTCAG CACACAAGGA AACAAAGCCC TGACAATCAG AGTGACTCCC TGGTGACTAA GCTCCAGTCC TGGATGCATA TTTGTTTAGC AGTTCTGACA GCATCTGACC CAGCCCTCTC TTTGCATACC CCACCAGAAC CTTCTTTTTT TTTTTTTTTC TTTGAGACTG AGTCTTGCTC TGTCGGAAGC GATTCCCGTG CCTCAGCCTC CCAAATACCT GGAATTATAG GCGTAAGCCA TCATGCCTGG CTAATTTTTG TATTTTTCAT GGAGATGGGG TTTTGCCATG TTGGTCAAAT TGGTCTCACA CTCCTGACCT CATGTGATCC ACCTGCCTCA GCCTCCCAAA GTGCTGGGAT GACAGGTGTA AGCCACCATG CTAGGCTCAG AAATTTCCTT TTATAAAAAT GTCATTAAGG ATCTTGGCTG CACAATATCG TTACCAGCTT CCTTTAAATC CACCTCTGGC CTGCCAGGAA TCAGGGTTCT TCAGAACCTG ACATTTTAAA TGAAGAGGTC

AGGCAGGTCA TGAGGAAAGC CTCATTGTCC CCATGTCTCT GTCACTGCTG CACCCCTGAG ACATCACAGA CATGGACACT GGGGCCTGCT TGTTTCTCAA ACTGCCCTTA GATCGAAAGA GGGAGGAACC AGGATGAATG CCACTCATTT TCCCAAGAAA GGCCCTCTCC TGAGTGCCCG GGATGGGGCT CTGTCCATTG CCTGGGGCCG CCAATTGCTA CTCTGGGTTA CGGAAGAAGG ACAGGGTCCT GAGAGACACC AGAGACCTCA CACAGCCCTG AAAACATGGG GCTCCTTCAT AAGTGTTTCC CATCACCAAC AGGGAGACCA CGTGGAGGCC TTGCAGCCCT ACTCGGTGCT TCTCCACCAA ATCCCAAGGG CAGTGACGCT GACGTCTGTG GAAAGCAGAG AAAGCCCTGG CTCCCAAAGC CCTGAAGTCC TGTGGAGCTG ACATTCCCTG AGTGACGGTG TGAATGGAAG GAACTCAAGT GCGGGTGGTA GGCCACCTCC TGGCCCAGOC CTGGGTGAAC TCTGAGGGGA CACATGTAGT

CACAATCCCA TCCTCCCATT CTCCTTCTCA GAGGAAGGAA GTGGGCATCC ATCTGCCTCA TCTCTCTCCC GTGGGGAAGA TGGGGAGTTT CAGGGGAACT TTCACATAAA TTTCACCAGC TCAGATCTCC TGTGAGGATG GGGCCCACCA TGCTCCCGGT GCTGCCAGAG GCCCTGAGCC CCTCCAGGGT CCCTGGGTTT GAGCCAGCCC TGTATCATCC CCAGGAGCTG AATGTCCGAA CAATGGATAG AATTAGATGG AAAGAGCTCT CAATTTGGCC TGAGACTGTC CCCAGATACT CAGGAAAAAC AGGACGTCGC ACAGAGTGGG CAGCAGGTGA GTGGCAGGTT ATAGGTCCTG AGTTTGAGTT TGTTCTCACG TGAGACAGAC CCAGCCCCTC ACTCCATTCA CACACTGGGT TTTAAATGGT GCAAGATAGG AGGAATTTTC TGGTCCCAAG AGCAGGAGGA AGGGATTTTC TGGGGTTTCC TGAGTCCAGA TTTGCATAAG ATCTCCTGAG TGTGCATTGT TCTTTGAGGA

CCATTCTCTG ACTCACCAGG TAAGTGGCTG AATTCTAACC TCTGTAATGA GCATTGCACC CAATACCAGT TCTGAACTCT ACCTGGTGAC CAGGGACCAG GACCTTTATA

AGGTGGAAGG CTTGATGTCC TCCCCAGACT CAGCTCCTGG TGAAGCTCCC AGCCATCAGC CATGAGGGTC TTGTATCTCC TCTTCTCGTT CCTCTTCATA TTCCTGATGC CTCTTCCAGG TGAGATGGGC CAGGGAAATA GGAGGGTTGG CCAAATGGAA GAATGGCGTA GAAGTTCTCT GTCTCCTCTC ATTCCCCTCC ACCTATCTCT CCCTCATCCC

TCTCTCTCCT TCCTCTCTCT GTGTGTCCCC TCCATCCTTT TCTCCTGCTT CTCTCTCTTC TTCCCTCTCT CTCTTTTTTT CTGTCTTTCT TTTTCCTCTC TCCCTAGAGC ATGTCTTTCT TTCTTTCTCT TTCCTTTCTT CTACCCACAC TTTTAGACTG AGTAGACTGA ATGCCCTATT TAATTGAACC AAGCATTGCT TCCTTCAATA GAAAAGGAGT

TTGAGAACCC AATGGACAAC TCACTCGTTC TTCTAAGCCA ATATGAAGGA GCCCAGTAGT TTGTAAATAT CATCTCTTCA CTGCTTTCCA TGCTACAACT GCTGAGACTA TGGTTGAAAC CTGTTAGGTG ACTTTTTAAA TAAAAGGCAG AAATTTTGAT TTTATCTAAA GAAAGTAGTA TAGAATGTCA TTTTCTAAAT TTTTATATTT AAAGAGTAGA TACTGCAACC TAGAGAATTC CAGATAATCT TAAGGCCCAG CCTATACTGT GAGAACTACT GCAGCAGACA CTCTGCCCCC AGGACTTTTC TGATCAGAGG CCCTGAGAAC AGTCCCTGCC ACTAGGCCAC TGCAGGTTCA CAGGACAGGG ACAGCCCATT GAAACCAACT TTTAAACCTG GATGCCTAAC CTTCATTTTC TCCTTGATAT TATGAAAATA AAATAAAAAC CATGAAAGGA TAAAAGAGGG AGAGTGGAAG GGAAGGATGG AGAAAGGGAA AAAGAAAATT TGAGAGTAAA TCCTAAAACA ATTAATCTAA

TAGATATCAT CTTGTGAAAT CCTCATTTTA CCAATCTTAT TTATGAGTCC TGGGTTTTGT GAGAACAATG GGGTTCTGAG AGGCACCAGA GACCTCATAT TTTCCAAAAC CTAGAACAGT ATAATGAAGG AAGGAGGGAA GGAGGGAGGG AGGGAGGGAA GGAGGGAAGG AGGGAGGGAG GGAGGGAAAC AAAAAGAAGA ATGAGGTTGA AACCAGGACT TAGATATTAG AAACAAGCCA TTACAAAATT TATTTCTATG GTTAATTGTG GTTTTCAACT GTAAGTTACT TGGTGTTAAT TTCCTATTAA ACAATTTCAG TAAGTTGCAT CTTTTTTATC CCATCTCAGA TCAAATACTT AACAGACTAA ATGATTTGAA AAAGCAAAAG TTTACTGGCT TGTGTGTGTT AAAATGGAGG TATGGTGGCT TTGATATTAT CTTCTTGTGG TGGAGCTGAA TTCACAAGAG ATCGTTGCTG AGCTCCTGCC AGACCCCACC TGGAGGCCCC AGTCACTCAG GAGAGATCAG GGTCTTTCAC

AATCAGGTTC TACAAAAATA AACATCCCCC AAACCACAGC AGTGCCAGTT TCCATGTCAG AAACTTAGAT CCAAATGACT GACTCGCGTC TCATTATCAT GATGGAAAAG CCCAGGCTTG AGAAAGAAGC CCGCTGCGGA TTTACTCAAG GCGATACTGA CACAGGGTTT GTGTTTTTCC AACATGAGTT TTGAGTTCTT ACACGCTGTT TGCTCTTTTT GTGTGTTTTT TCCCTGTTAG GTGTTTTTGG TGGTATAGGC GATCCTGTTA CCTGCCTTAA GAGTGGAGCC ATATGTCATC CAGTCTTTTG CCCTAGAAGG TATAAACAAA TTGGCACCTG TGGTCTCCCT GGAACAAAAT GCTGCAAAAA GCCATGAGGA GGCCAAGAAG CTGCTGTGGC TGATGCGGAT TCAGAAAGGG CTCCCTCATC AGAGACGTGC GACATGTAAA CCAAATTAAA CTATGGTGTC CAAAGATACG CAATCTTTAT CCTAGTAATT GTGGTCATTG GGTGATGTTG GTTTGGGCAG GCCATCTCTA ATATCCTTGA

AACACCTTTT TCTGCTCTCC AGGAAGGGGT CAGGGCTGCC ACAGCGGGGC TTGGAGTGC-3' (FRAG NO ) (SEQ ID NO 12380)

5'-GAATTCACAT TTCTCACCTT TTGATGTATT AAGAAAGTAT GGAGAAATAT ATCCTCTATC AAATTTTCAT GCCTTCAATA ATTTCTAATT CATCAGTCAG TGTTTTTCCA TCCTTTACTG TGATGATGCC CTTTCTTCCA AACTTTTTCA TTGCATCAGA GATGATGTTA CCAATTTCTT TGTCTCCATT TGCAGAAATT GTAGCAACCT GTGCAATTTC TTCAGGTTTG GTCACAGGTT TAGACTGCTT TTTAAGTTCA GCAATTACAG CATCAACAGC TAACATCACA CCTCTCTTGA TTTCCACTGG ATTAGCACCT TTGCTAACCT TCTGGAAGGC TTATTTGGAA ATAGAGCATA CCAGTACAGC AGCAGTGATA GTGCCATCCC CCAGTCTCTC CATTTGTGTT ATTGGCAACA TCTTGGACAA GTTTAGCTCC

AATGCTTTTA TATTTATCCT TTAAGTCAAT TGACTTTGCA TCAGTCACAC CATCTTTTGT TACTTTGGGA CTTCCCCAGC TATGTTCAAT AATTACTGTT CTTCCCTTTG GCCCCATTGT AATGGCTACA GCATCGACAA AAAGTCTACA CTTTGAAGCA TTAAGGCTCA GACATCAGCA CCAAATTTTA CATCTTTACC ATCACTTCAA GTGAGGTGAG GAGCCAGTAG CCTGGACACT GGTCTCATCT GGTGAAAGAC TGTGGGTAAT GGAAGCATTT CTGTGGGGTG GTGGCAGGAC ATGTGCATGG TGAGGCAGGT CATCAGCAGC AAGTGAGAGC TGCCTCTTAC TTTCTAAAGG TGACATAGCA AGTATACAAA AAAAAATAAA ATATTAATTT AGGCAGAGCA CATAAAGGCT TTATTTCATA TTCCATTTCT CTGTATGCTT TCTTCACCAG GAAGAAATAG TTTTAGTGTC AGGAATGAAT GAGTCTGCCC CTCAATTCCA GCCTGCTCAG CACACAAGGA AACAAAGCCC TGACAATCAG

AGTGACTCCC TGGTGACTAA GCTCCAGTCC TGGATGCATA TTTGTTTAGC AGTTCTGACA GCATCTGACC CAGCCCTCTC TTTGCATACC CCACCAGAAC CTTCTTTTTT TTTTTTTTTC TTTGAGACTG AGTCTTGCTC TGTCGGAAGC GATTCCCGTG CCTCAGCCTC CCAAATACCT GGAATTATAG GCGTAAGCCA TCATGCCTGG CTAATTTTTG TATTTTTCAT GGAGATGGGG TTTTGCCATG TTGGTCAAAT TGGTCTCACA CTCCTGACCT CATGTGATCC ACCTGCCTCA GCCTCCCAAA GTGCTGGGAT GACAGGTGTA AGCCACCATG CTAGGCTCAG AAATTTCCTT TTATAAAAAT GTCATTAAGG ATCTTGGCTG CACAATATCG TTACCAGCTT CCTTTAAATC CACCTCTGGC CTGCCAGGAA TCAGGGTTCT TCAGAACCTG ACATTTTAAA TGAAGAGGTC AGGCAGGTCA TGAGGAAAGC CTCATTGTCC CCATGTCTCT GTCACTGCTG CACCCCTGAG ACATCACAGA

CATGGACACT GGGGCCTGCT TGTTTCTCAA ACTGCCCTTA GATCGAAAGA GGGAGGAACC AGGATGAATG CCACTCATTT TCCCAAGAAA GGCCCTCTCC TGAGTGCCCG GGATGGGGCT CTGTCCATTG CCTGGGGCCG CCAATTGCTA CTCTGGGTTA CGGAAGAAGG ACAGGGTCCT GAGAGACACC AGAGACCTCA CACAGCCCTG AAAACATGGG GCTCCTTCAT AAGTGTTTCC CATCACCAAC AGGGAGACCA CGTGGAGGCC TTGCAGCCCT ACTCGGTGCT TCTCCACCAA ATCCCAAGGG CAGTGACGCT GACGTCTGTG GAAAGCAGAG AAAGCCCTGG CTCCCAAAGC CCTGAAGTCC TGTGGAGCTG ACATTCCCTG AGTGACGGTG TGAATGGAAG GAACTCAAGT GCGGGTGGTA GGCCACCTCC TGGCCCAGGC CTGGGTGAAC TCTGAGGGGA CACATGTAGT CACAATCCCA TCCTCCCATT CTCCTTCTCA GAGGAAGGAA GTGGGCATCC ATCTGCCTCA

TCTCTCTCCC GTGGGGAAGA TGGGGAGTTT CAGGGGAACT TTCACATAAA TTTCACCAGC TCAGATCTCC TGTGAGGATG GGGCCCACCA TGCTCCCGGT GCTGCCAGAG GCCCTGAGCC CCTCCAGGGT CCCTGGGTTT GAGCCAGCCC TGTATCATCC CCAGGAGCTG AATGTCCGAA CAATGGATAG AATTAGATGG AAAGAGCTCT CAATTTGGCC TGAGACTGTC CCCAGATACT CAGGAAAAAC AGGACGTCGC ACAGAGTGGG CAGCAGGTGA GTGGCAGGTT ATAGGTCCTG AGTTTGAGTT TGTTCTCACG TGAGACAGAC CCAGCCCCTC ACTCCATTCA CACACTGGGT TTTAAATGGT GCAAGATAGG AGGAATTTTC TGGTCCCAAG AGCAGGAGGA AGGGATTTTC TGGGGTTTCC TGAGTCCAGA TTTGCATAAG ATCTCCTGAG TGTGCATTGT TCTTTGAGGA CCATTCTCTG ACTCACCAGG TAAGTGGCTG AATTCTAACC TCTGTAATGA GCATTGCACC CAATACCAGT

TCTGAACTCT ACCTGGTGAC CAGGGACCAG GACCTTTATA AGGTGGAAGG CTTGATGTCC TCCCCAGACT CAGCTCCTGG TGAAGCTCCC AGCCATCAGC CATGAGGGTC TTGTATCTCC TCTTCTCGTT CCTCTTCATA TTCCTGATGC CTCTTCCAGG TGAGATGGGC CAGGGAAATA GGAGGGTTGG CCAAATGGAA GAATGGCGTA GAAGTTCTCT GTCTCCTCTC ATTCCCCTCC ACCTATCTCT CCCTCATCCC TCTCTCTCCT TCCTCTCTCT GTGTGTCCCC TCCATCCTTT TCTCCTGCTT CTCTCTCTTC TTCCCTCTCT CTCTTTTTTT CTGTCTTTCT TTTTCCTCTC TCCCTAGAGC ATGTCTTTCT TTCTTTCTCT TTCCTTTCTT CTACCCACAC TTTTAGACTG AGTAGACTGA ATGCCCTATT TAATTGAACC AAGCATTGCT TCCTTCAATA GAAAAGGAGT TTGAGAACCC AATGGACAAC TCACTCGTTC TTCTAAGCCA ATATGAAGGA GCCCAGTAGT TTGTAAATAT

CATCTCTTCA CTGCTTTCCA TGCTACAACT GCTGAGACTA TGGTTGAAAC CTGTTAGGTG ACTTTTTAAA TAAAAGGCAG AAATTTTGAT TTTATCTAAA GAAAGTAGTA TAGAATGTCA TTTTCTAAAT TTTTATATTT AAAGAGTAGA TACTGCAACC TAGAGAATTC CAGATAATCT TAAGGCCCAG CCTATACTGT GAGAACTACT GCAGCAGACA CTCTGCCCCC AGGACTTTTC TGATCAGAGG CCCTGAGAAC AGTCCCTGCC ACTAGGCCAC TGCAGGTTCA CAGGACAGGG ACAGCCCATT GAAACCAACT TTTAAACCTG GATGCCTAAC CTTCATTTTC TCCTTGATAT TATGAAAATA AAATAAAAAC CATGAAAGGA TAAAAGAGGG AGAGTGGAAG GGAAGGATGG AGAAAGGGAA AAAGAAAATT TGAGAGTAAA TCCTAAAACA ATTAATCTAA TAGATATCAT CTTGTGAAAT CCTCATTTTA CCAATCTTAT TTATGAGTCC TGGGTTTTGT GAGAACAATG

GGGTTCTGAG AGGCACCAGA GACCTCATAT TTTCCAAAAC CTAGAACAGT ATAATGAAGG AAGGAGGGAA GGAGGGAGGG AGGGAGGGAA GGAGGGAAGG AGGGAGGGAG GGAGGGAAAC AAAAAGAAGA ATGAGGTTGA AACCAGGACT TAGATATTAG AAACAAGCCA TTACAAAATT TATTTCTATG GTTAATTGTG GTTTTCAACT GTAAGTTACT TGGTGTTAAT TTCCTATTAA ACAATTTCAG TAAGTTGCAT CTTTTTTATC CCATCTCAGA TCAAATACTT AACAGACTAA ATGATTTGAA AAAGCAAAAG TTTACTGGCT TGTGTGTGTT AAAATGGAGG TATGGTGGCT TTGATATTAT CTTCTTGTGG TGGAGCTGAA TTCACAAGAG ATCGTTGCTG AGCTCCTGCC AGACCCCACC TGGAGGCCCC AGTCACTCAG GAGAGATCAG GGTCTTTCAC AATCAGGTTC TACAAAAATA AACATCCCCC AAACCACAGC AGTGCCAGTT TCCATGTCAG AAACTTAGAT

CCAAATGACT GACTCGCGTC TCATTATCAT GATGGAAAAG CCCAGGCTTG AGAAAGAAGC CCGCTGCGGA TTTACTCAAG GCGATACTGA CACAGGGTTT GTGTTTTTCC AACATGAGTT TTGAGTTCTT ACACGCTGTT TGCTCTTTTT GTGTGTTTTT TCCCTGTTAG GTGTTTTTGG TGGTATAGGC GATCCTGTTA CCTGCCTTAA GAGTGGAGCC ATATGTCATC CAGTCTTTTG CCCTAGAAGG TATAAACAAA TTGGCACCTG TGGTCTCCCT GGAACAAAAT GCTGCAAAAA GCCATGAGGA GGCCAAGAAG CTGCTGTGGC TGATGCGGAT TCAGAAAGGG CTCCCTCATC AGAGACGTGC GACATGTAAA CCAAATTAAA CTATGGTGTC CAAAGATACG CAATCTTTAT CCTAGTAATT GTGGTCATTG GGTGATGTTG GTTTGGGCAG GCCATCTCTA ATATCCTTGA AACACCTTTT TCTGCTCTCC AGGAAGGGGT CAGGGCTGCC ACAGCGGGGC TTGGAGTGC-3' (FRAG

NO ) (SEQ D NO 11845)

5'-ATCCTTTAAG TCAATGGACT TTGCATCAGT CACACCATCT TTTGTTACTT TGGACTTCCC CAGCTATGTT CAATAATTAC TGTTCTTCCC TTGGGCCCCA TTGTAATGGC TACAGCCTCG ACAAAAAGTC TACACTTTGA AGCATTAAGG CTCGGACATC AGCACCAAAT TTTACATCTT TACCATCACT TCAAGTGAGG TGAGGAGCCA GTAGCCTGGA CACTGGTCTC ATCTGGTGAA AGACTGTGGG TAATGGAAGC ATTTCTGTGG GGTGCTGGCA GGACATGTGC ATGGCGAGGC AGGTCATCAG CAGCAAGTGA GAGCTGCCTC

TTACTTTCTA AAGGTGACAT AGCAAATATA CAAAAAAAAA TAAATAAATT ATTAATTTAG GTAGAGCACA TAAAGGCTTT ATTTCATATT CCATTTCTCT GTATGCTTTC TTCACCAGGA AGAAATAGTT TTAGTGTCAG GAATGAATGA GTCTGCCCCT CAATTCCAGC CTGCTCAACA CACAAGGAAA CAAAGCCCTG ACAATCAGAG TGACTCCCTG GTGACTAAGC TCCCAGTCCT GGATGCATAT TTGTTTAGCA GTTCTGACAG CATTTGACCC AGCCCTCTCT CTGCATATCC CATCAGAACC TTCTTTTTTT TTTTTTTCTT TGAGACTGAG TCTTGCTCTG TCGGAAGCGA CTCCTGTGCC TCAGCCTCCC AAATACCTGG AATTATAGGC GTAAGCCATC ATGCCTGGCT AATTTTTGTA TTTTTCATGG AGATGGGGTT TTGCCATGTT GGTCAAATTG GTCTCACACT CCTGACCTCA TGTGATCCAC CTGCCTCAGC CTCCCAAACT GCTGGGATGA CAGGTGTAAG CCACCATGCT

AGGCTCAGAA ATTTCCTTTT ATAAAAATGT CATTAAGGAT CTTGGCTGCA CAATATCGTT ACCAGCTTCC TTTAAATCCA CTTCTGGCCT GCCAGGAATC AGGTTCTTCA GAACCTGACA TTTTAAATGA AGAGGTCAGG CAGTTCATGA GGAAAGCCTC ATTGTCCCCA TGTCTCTGTC ACTGCTGCAC CCCTGAGACA TCACAGACAT GGACACTGGG GCCTGCTTGT TTCTCAAACT GCCCTTAGAT CGAAAGAGGG AGGAACCAGG ATGAATGCCA CTCATTTTCC CAAGAAAGGC CCTCTCCTGA GTGCCCGGGA TGGGGCTCTG TCCATTGCCT GGGGCCGCCA ATTGCTACTC TGGGTTACGG AGGAAGGACA GGGTCCTGAG AGACACCAGA GACCTCACAC AGCCCTGAAA ACATGGGGCT CCTTCATAAG TGTTTCCCAT CACCAACAGG GAGACCACGT GGAGGCCTTG CAGCCCCACT CGGTGCTTCT CCACCAAATC CCAAGGGCAG TGACGCTGAC GTCTGTGGAA AGCAGAGAAA

GCCCTGGCTC CCAAAGCCCT GAAGTCCCTG TGGAGCTGAC ATTCCCTGAG TGACGGTGTG AATGGAAGGA ACTCAAGTGC GGGTGGTAGG CCACCTCCTG GCCCAGGCCT GGGTGAACTC TGAGGGGACA CATGTAGTCA CAATCCCATC CTCCCATTCT CCTTCTCAGA GGAAGGAAGT GGGCATCCAT CTGCCTCATC TCTCTCCCGT GGGGAAGATG GGGAGTTTCA GGGGAACTTT CACATAAATT TCACCAGCTC AGATCTCCTG TGAGGATGGG GCCCACCATG CTCCCGGTGC TGCCAGAGGC CCTGAGCCCC TCCCAGGGTC CCTGGGTTTG AGCCAGCCCT GTATCATCCC CAGGAGCTGA ATGTCAGAGC AATGGATAGA ATTAGATGGA AAGAGCTCTC AATTTGACCT GAGACTGTCC CCAGATACTC AGGAAAAACA GGACGTCGCA CAGAGTGGGC AGCAGGTGAG TGGCAGGTTA TAGGTCCTGA GTTTGAGTTT GTTCTCACGT GAGACAGACC CAGCCCCTCA CTCCATTCAC

ACACTGGGTT TTAAATGGTG CAAGATAGGA GCAATTTTCT GGTCCCAAGA GCAGGAGGAA GGGATTTTCT GGGGTTTCCT GAGTCCAGAT TTGCATAAGA TCTCCTGAGT GTGCATTGTT CTTTGAGGAC CATTCTCTGA CTCACCAGGT AAGTGGCTGA ATTCTAACCT CTGTAATGAG CATTGCACCC AATACCAGTT CTGAACTCTA CCTGGTGACC AGGGACCAGG ACCTTTATAA GGTGGAAGGC TTGATGTCCT CCCCAGACTC AGCTCCTGGT GAAGCTCCCA GCCATCAGCC ATGAGGGTCT TGTATCTCCT CTTCTCGTTC CTCTTCATAT TCCTGATGCC TCTTCCAGGT GAGATGGGCC AGGGAAATAG GAGGGTTGGC CAAATGGAAG AATGGCGTAG AAGTTCTCTG TCTCCTCTCA TTCCCCTCCA CCTATCTCTC CCTCATCCCT CTCTCTCCTT CCTCTCTCTG TGTGTCCCCT CCATCCTTTT CTCCTGCTTC TCTCTCTTCT TCCCTCTCTC TCTTTTTTCT GTCTTTCTTT

TTCCTCTCTC CCTAGAGCAT GTCTTTCTTT CTTTCTCTTT CCTTTCTTCT ACCCACACTT TTAGACTGAA TGCCCTATTT AATTGAACAA AGCATTGCTT CCTTCAATAG AAAAGGAGTT TGAGAACCCA ATGGACACCT CACTCGTTCT TCTAAGCCAA TATGAAGGAG CCCAGTAGCT TGTAAATATC ATCTCTTCAC TGCTTTCCAT GCTACAACTG CTGAGACTAT GGTTGAAACC TGTTAGGTGA CTTTTTAAAT AAAAGGCAGA AATTTTGATT TTATCTAAAG AAAGTAGTAT AGAATGTCAT TTTCTAAATT TTTATATTTA AAGGGTAGAT ACTGCAACCT AGAGAATTCC AGATAATCTT AAGGCCCAGC CTATACTGTG AGAACTACTG CAGCAAGACA CTCTGCCTCC AGGACTTTTC TGATCAGAGG CCCTGAGAAC AGTCCCTGCC ACTAGGCCAC TGCAGGTTCA CAGGACAGGG TACAGCCCAT TGAAACCTAC TTTTAAACCT GGATGCCTAA CCTTCATTTT CTCCTTGATA

TTATGAAAAT AAAATAAAAA CCATGAAAGG ATAAAAGAGG GAGAGTGGAA GGGAAGGATG GAGAAAGGGA AAAAGAAAAT TTGAGAGTAA ATCCTAAAAC AATTAATCTA ATAGATATCA TCTTGTGAAA TCCTCATTTT ACCAATCTTA TTTATGAGTC CTGGGTTTTG TGAGAACAAT GGGGTTCTGA GAGGCACCAG AGACCTCATG TTTTCCAAAA CCTAGAACAG TATAATGAAG GAAGGCGGGG AGGCAGGGAG GCAGGGAGGC AGGGAGGCAG GGAGGCGGGC AGGTGGGGAG GGAGGGACGG AAGGAGGGAG GGAGGGAGGG AGGGAGGGAG GGAGGGATAA AAAAAGAAGA ATGAGGTTGA AACCAGGACT TAGATATTAG AAACAAGCCA TTACAAAATT TATTTCTATG GTTAATTGTG GTTTTCAACT GTAAGTTACT TGGTGTTAAT TTCCTATTAA ACAATTTCAG TAAGTTGCAT CTTTTTATCC CATCTCAGGT CAAATACTTA

ACAGACTAAA TGATTTGAAA AAGCAAAAGT TTACTGGCTT GTGTGTGTTA AAATGGAGGT ATGGTGGCTT TGATATTATC TTCTTGTGGT GGAGCTGAAT TCACAAGAGA TCGTTGCTGA GCTCCTACCA GACCCCACCT GGAGGCCCCA GTCACTCAGG AGAGATCAGG GTCTTTCACA ATCAGGTTCT ACAAAAATAA ACATCCCCCC AACCACAGCA GTGCCAGTTT CCATGTCAGA AACTTAGATC CAAATGACTG ACTCGCGTCT CATTATCATG ATGGAAAAGC CCAGGCTTGA GAAAGAAGCC CGCTGCGGAT TTACTCAAGG CGATACTGAC ACAGGGTTTG TGTTTTTCCA ACATGAGTTT TGAGTTCTTA GACGCTGTTT GCTCTTTTTG TGTGTTTTTT CCCTGTTAGG TGTTTTTGGT GGTATAGGCG ATCCTGTTAC CTGCCTTAAG AGTGGAGCCA TATGTCATCC AGTCTTTTGC CCTAGAAGGT ATAAACAAAT TGGCACCTGT GGTCTCCCTG GAACAAAATG CTGCAAAAAG

CCATGAGGAG GCCAAGAAGC TGCTGTGGCT GATGCGGATT CAGAAAGGGC TCCCTCATCA GAGACGTGCG ACATGTAAAC TATGGTGTCC AAAGATACGC AATCTTTATC CTAGTAATTG TGGTCATTGG GTGATGTTGG TTTGGGCAGG CCATCTCTAA TATCCTTGAA ACACCTTTTT CTGCTCTCCA GGAAGGGGTC AGGGCTGCCA CAGCGGGGCT TGGAGTGCTT TCCAGGGTCA CAGGCATCTG TATTCTTTGG ATTCCTTGAC CTTCCCCATT TATTCCCGGC ATTTTCCTAA AACGTGTGCT TTGCTCCTCC TGCATCCTCC CCTTGCATGC CCTCACCTAC CCCACATCTT CCCTAAAAAA AGCAAGCCCA ACTCAAAGAC CAGTTCCCTC ATGGAATCAT AGTGGATCTG CCAAGGGAGG GGATGCCCAG TCCTCTGTTC TTCACAAGAC TCCCTTCTTC TGGCTAAGGT TTCTTATGCA ATTAT GAATTCCCTG TAAGCCCTGT TACAGGGGCT GCACOCCAGA

TACAACCTGA CCTGTGTCCA AGGCGGGCAA CTCAACCCTT AGATATTGAA TGGGTCCCAT GGCACCAATG CTTAAACACC AGCAGCCCTC ACAACCACAG ATCGTGTTTT AAGGATGAGG AGGTAGTTCT CTGGATGCAC AGGCTTCAAT CCAAATGGGC TCATGACGCC GCAGCACACA CCCAGTCTGC AGCCTGAAGA GTTGGAGCAT TGCATTCACA GAAAGCATCC AGACATGATC ATGGGCTCAG GGATACACCT GTTCTCCGAT GTGTACCAGT GAAGGATGGA AACTCCTATG CCTCCCAGAA AGCACCACTC AAGCTTTTGC TGAATGCTTC TCTGAAGGCC CACAAGGCTG AGAGGCTGTG CAACACCAGC AGTAAAGTGA ATGCCCAGAC TCCCACCTCC TTTCTTGGGT GGCCATCTGG AAAGGCCACT CCCACCCTGA TGGCTAATGC CTCAGACCAG TTCTTGGCCC AGATGATCCT AGACAATTGT TTAAGCTTAA ACTGTTCATT GGCCAAGCAA ACAGGTGATA GTACCTCTGG

GGAACCACAT GCCGCGTGTA CATCCAGATC TCAGGAGAAC CCAAAAATGT CTGTTCCACA TAGCAACAGA AGCCCAGGTA GCACTCAGTC TCACCTGGGT GTTCTCCAAC ATCCCAGCTC AGCCAAATGG CTTTCATTAG TTTTTATGGT TAGACCCCAG GTCCTCGGGA CACTGCTTTA GAAACACATT CCAAATCCTC CTCTGTGTGC AGGTGGCATT CCTATCCCAA TCTCTTTGCA GGGCGTATAC TGTGATACGC AGCCAGGCTG TCCCAGAGGC CTTAAATATT CCCTTGGTGC AGGTAGTTCA GCTTAGCCAC AGCCAATGCA TCACAGGGTC AACTGTGTTA GGAGCCATTG AGAATCCATA GTTGGTTGCT GCCTGGGCCT GGCCAGGGCT GACCAAGGTA GATGAGAGGT TCCTCTGTGG AGTTCTACTT TAACCTCACC TTCCCACCAA ATTTCTCAAC TGTCCTTGCC ACCACAATTA TTTAATGGAC CCAACAGAAA GTAACCCCGG AAATTAGGAC ACCTCATCCC AAAAGACCTT

TAAATAGGGG AAGTCCACTT GTGCACGGCT GCTCCTTGCT ATAGAAGACC TGGGACAGAG GACTGCTGTC TGCCCTCTCT GGTCACCCTG CCTAGCTAGA GGATCTGTAA GTACTACAAA ACTTAAACTT TACACTGAGT TTTCATCATT GAAGCTATGC CTCCAATCTG ACCTCTGACT GTGGGGCCGC CCCAGAGGGA CCCAGCGGGT GAATCCCTGC TAGGAACGTC TGTCCGGACC TCTGGTGACT GCTGGGGACG ATGGCTTCCA GCTAACTTAA TAGAGAAACT CAAGCAGTTT CCTTCTAAAT ACACATGTCA CATGTCCTGG TTGACATGTC CAGTAAGAAG ACTATCACAG GTCTTTGGAA CATTCTTTTG AGAGAAACCT ATTTAGGTCC TTGGTCTGTT TTTCAATCAG GTTGTTTGAT TTTTGCTATT GAGTTGTTGG AATTCCTTAT GTATTCAGAT ATTTGCCCCT TCTGCCATGT AGGTTTTGCA AATATTTTCT CTCATTTTCT GGGTTATCTT TTCACTCGGT TGATTGTTTC

CTTTGCTGTG CAGATGCTTT AGCGTTAAAT GAAGCCACAC TTGTCTATTT TCCCTTTTAT TGCCTGTGCC TTTGGTGTCA TAGCCAAGAA ATCATTACCT ACATCAATGT CAAAAGCTTT ATCCTTCTAT ACACTTCTAG TAGTTTATGG TTTCAGTTGT TACATTTAGG TTTTCAATTC ATTCTGAGTT GATGTTCCTA CATGGTGTGA GATAAAGATT TAAATACATA CATATATAAA ATCATGAGGT AGTGTACACT ATAAATATAC AATTGTTAAT TGTTACTCAA GTCTAAGTAG AGGTGGAAAT AATAAACTTT CTTTTTTTTA CTTAAACCAC TCTGTGTCAC TGAGCTGATT TCACCTTTAG CCTGATAAAA TCATTGTCCT CTCCACCCTG ATTCCTACAG GAGACTACTC ACCCCATAAC CTCAAAAACC TCTTCATGAG GATGGTAAGT CACCTGAATC CTGAAGTGAA TTACTCGCTA TTCCATTGGA ACTCATATAG GACACCAGAA TCTAGACCTC CAGAGAACAG CAGGACCCAT

CTTCAGAAAA TAAGAAGCAT TTGTTCCCTG AGCCTGTTGA ATCAAAGTGC AATTTCTATT CTTTTTGGAA TGTTAAAAAG TGAATCATAA TATTTAAGCA GGTGAACCCA CGAGTAACAT AGCAGGGTCT TTCTTGTCAT TATTAGCTCC AACCTAGCAC AGACATTAAA GGTACAGATG TATACTAGCA TGAAACTGGG AGAACAGGAG CATTCGAGCA ACCTTGAGAC CAATGGGCCT CTCTTATAAA ATGCACACCT CCTCTCACTG AGATTGAGGA AGGTTTCTTG TCTCCGAGCC TTCTCCCAGT AGAGCTATAA ATCCAGGCTG GCTCCTCCCT CCCCACACAG CTGCTCCTGC TCTCCCTCCT CCAGGTGACC CCAGCCATGA GGACCCTCGC CATCCTTGCT GCCATTCTCC TGGTGGCCCT GCAGGCCCAG GCTGAGCCAC TCCAGGCAAG AGCTGATGAG GTTGCTGCAG CCCCGGAGCA GATTGCAGCG GACATCCCAG AAGTGGTTGT TTCCCTTGCA TGGGACGAAA GCTTGGCTCC

AAAGCATCCA GGTGAGAGAG GCAGGCATGC AGAGCTGCTA AGTCTAGAGG GAAGGACGGG AGAGAGGTTC CAGAGTTGGG TCTCAGCAGT CTATGTCACT GAGGTGGCTT CACTTAGAAT CTCTGGGCAT TGATTTTCTC ATCTAGAAAT TGAACAGAGA GCCAAATAAA CCTGAGAAAC TTTATTTCTC CAAAGACTTG ATTCCAAGAA ACATCTGTGA AATTCACTAA GTTTAAGATA TGAAGAGACA GACTAGTTAT TTCTGGATCT AAACAAGTAG ACTTAGTTGT AAAGAGAACA TTTTACTCTA TCTACAGAAG AGCTTTTAAA AACTGCAGCC AAGCCTGAGG GTAAGTTCAG GTGTGTGTGT GATGGGGCAG GAATGCAAAA ATGAGAGCAA AGGAGAATGA GTCTCAAATT CTGTGTGACA AGCACTGCTC TGCGTGTTTA TTCCTATCGA CTGAGGTTGT TCGTGCTACC GGCTGCAATG CAGCCAGCAT CACCTGTCAG CTAGCATGTG ACTTCCCCGA GATTCTTTTT CTTACCCACT GCTAACTCCA TACTCAATTT CTCATGCTCT CCCTGTCCCA GGCTCAAGGA AAAACATGGA CTGCTATTGC AGAATACCAG CGTGCATTGC AGGAGAACGT CGCTATGGAA CCTGCATCTA CCAGGGAAGA CTCTGGGCAT TCTGCTGCTG AGCTTGCAGA AAAAGAAAAA TGAGCTCAAA ATTTGCTTTG AGAGCTACAG GGAATTGCTA TTACTCCTGT ACCTTCTGCT CAATTTCCTT TCCTCATCTC AAATAAATGC CTTGTTACAA GATTTCTGTG TTTCCACCTC TTTAATGTGT GATATGTGTC TGTGTCAAGA CACTTGGGAT ACACGTACCA AAACGCAAAA TCAAATTTTT GAACAATATA-3' (FRAG NO ) (SEQ ID NO 12381) Human Defensin 3 Nucleic Acid and Antisense Oligonucleotide Fragments

5*-CGCTGCBBTC TGCTCCGGGG CTGCBGCBBC CTCBTCBGCTC TTGCCTGGBGTG GCTCBGCCTGG GCCTGCBGGG CCBCCBGGBGB BTGGCBGCBBG GBTGGCGBGGG TCCTCBTGGC TGGGGTCBCCT GGBGGBGGGB GBGCBGGGGG TCCTCBTGGC TGGGGTCCCT CTCTCCCGTC CT CCTACCTTGC TATAGAAGAC CTGGGACAGA GGACTGCTGT CTGCCCTCTC TGGTCACCCT GCCTAGCTAG AGGATCTGTG ACCCCAGCCA TGAGGACCCT CGCCATCCTT GCTGCCATTC TCCTGGTGGC CCTGCAGGCC CAGGCTGAGC CACTCCAGGC AAGAGCTGAT GAGGTTGCTG CAGCCCCGGA GCAGATTGCA GCGGACATCC CAGAAGTGGT TGTTTCCCTT GCATGGGACG AAAGCTTGGC TCCAAAGCAT CCAGGCTCAA GGAAAAACAT GGACTGCTAT TGCAGAATAC CAGCGTGCAT TGCAGGAGAA CGTCGCTATG GAACCTGCAT CTACCAGGGA AGACTCTGGG

CATTCTGCTG CTGAGCTTGC AGAAAAAGAA AAATGAGCTC AAAATTTGCT TTGAGAGCTA CAGGGAATTG CTATTACTCC TGTACCTTCT GCTCAATTTC CTTT-3' (FRAG NO 1804) (SEQ DD NO 12382)

5'-CCTACCTTGC TATAGAAGAC CTGGGACAGA GGACTGCTGT CTGCCCTCTC TGGTCACCCT GCCTAGCTAG AGGATCTGTG ACCCCAGCCA TGAGGACCCT CGCCATCCTT GCTGCCATTC TCCTGGTGGC CCTGCAGGCC CAGGCTGAGC CACTCCAGGC AAGAGCTGAT GAGGTTGCTG CAGCCCCGGA GCAGATTGCA GCGGACATCC CAGAAGTGGT TGTTTCCCTT GCATGGGACG AAAGCTTGGC TCCAAAGCAT CCAGGCTCAA GGAAAAACAT GGACTGCTAT TGCAGAATAC CAGCGTGCAT TGCAGGAGAA CGTCGCTATG

GAACCTGCAT CTACCAGGGA AGACTCTGGG CATTCTGCTG CTGAGCTTGC AGAAAAAGAA AAATGAGCTC AAAATTTGCT TTGAGAGCTA CAGGGAATTG CTATTACTCC

TGTACCTTCT GCTCAATTTC CTTT-3' (FRAG NO ) (SEQ ID NO 11847)

5'-GAATTCCCTG TAAGCCCTGT TACAGGGGCT GCACCCCAGA TACAACCTGA CCTGTGTCCA AGGCGGGCAA CTCAACCCTT AGATATTGAA TGGGTCCCAT GGCACCAATG CTTAAACACC AGCAGCCCTC ACAACCACAG ATCGTGTTTT AAGGATGAGG AGGTAGTTCT CTGGATGCAC AGGCTTCAAT CCAAATGGGC TCATGACGCC GCAGCACACA CCCAGTCTGC AGCCTGAAGA GTTGGAGCAT TGCATTCACA GAAAGCATCC AGACATGATC ATGGGCTCAG GGATACACCT GTTCTCCGAT GTGTACCAGT

GAAGGATGGA AACTCCTATG CCTCCCAGAA AGCACCACTC AAGCTTTTGC TGAATGCTTC TCTGAAGGCC CACAAGGCTG AGAGGCTGTG CAACACCAGC AGTAAAGTGA ATGCCCAGAC TCCCACCTCC TTTCTTGGGT GGCCATCTGG AAAGGCCACT CCCACCCTGA TGGCTAATGC CTCAGACCAG TTCTTGGCCC AGATGATCCT AGACAATTGT TTAAGCTTAA ACTGTTCATT GGCCAAGCAA ACAGGTGATA GTACCTCTGG GGAACCACAT GCCGCGTGTA CATCCAGATC TCAGGAGAAC CCAAAAATGT CTGTTCCACA TAGCAACAGA AGCCCAGGTA GCACTCAGTC TCACCTGGGT GTTCTCCAAC ATCCCAGCTC AGCCAAATGG CTTTCATTAG TTTTTATGGT TAGACCCCAG GTCCTCGGGA CACTGCTTTA GAAACACATT CCAAATCCTC CTCTGTGTGC AGGTGGCATT CCTATCCCAA TCTCTTTGCA GGGCGTATAC TGTGATACGC AGCCAGGCTG TCCCAGAGGC CTTAAATATT CCCTTGGTGC AGGTAGTTCA GCTTAGCCAC AGCCAATGCA TCACAGGGTC AACTGTGTTA GGAGCCATTG AGAATCCATA GTTGGTTGCT GCCTGGGCCT GGCCAGGGCT GACCAAGGTA GATGAGAGGT TCCTCTGTGG AGTTCTACTT TAACCTCACC TTCCCACCAA ATTTCTCAAC TGTCCTTGCC ACCACAATTA TTTAATGGAC CCAACAGAAA GTAACCCCGG AAATTAGGAC ACCTCATCCC AAAAGACCTT TAAATAGGGG AAGTCCACTT GTGCACGGCT GCTCCTTGCT ATAGAAGACC TGGGACAGAG GACTGCTGTC TGCCCTCTCT GGTCACCCTG CCTAGCTAGA GGATCTGTAA GTACTACAAA ACTTAAACTT TACACTGAGT TTTCATCATT GAAGCTATGC CTCCAATCTG

ACCTCTGACT GTGGGGCCGC CCCAGAGGGA CCCAGCGGGT GAATCCCTGC TAGGAACGTC TGTCCGGACC TCTGGTGACT GCTGGGGACG ATGGCTTCCA GCTAACTTAA TAGAGAAACT CAAGCAGTTT CCTTCTAAAT ACACATGTCA CATGTCCTGG TTGACATGTC CAGTAAGAAG ACTATCACAG GTCTTTGGAA CATTCTTTTG AGAGAAACCT ATTTAGGTCC TTGGTCTGTT TTTCAATCAG GTTGTTTGAT TTTTGCTATT GAGTTGTTGG AATTCCTTAT GTATTCAGAT ATTTGCCCCT TCTGCCATGT AGGTTTTGCA AATATTTTCT CTCATTTTCT GGGTTATCTT TTCACTCGGT TGATTGTTTC CTTTGCTGTG CAGATGCTTT AGCGTTAAAT GAAGCCACAC TTGTCTATTT TCCCTTTTAT TGCCTGTGCC TTTGGTGTCA TAGCCAAGAA ATCATTACCT ACATCAATGT CAAAAGCTTT ATCCTTCTAT ACACTTCTAG TAGTTTATGG TTTCAGTTGT TACATTTAGG

TTTTCAATTC ATTCTGAGTT GATGTTCCTA CATGGTGTGA GATAAAGATT TAAATACATA CATATATAAA ATCATGAGGT AGTGTACACT ATAAATATAC AATTGTTAAT TGTTACTCAA GTCTAAGTAG AGGTOGAAAT AATAAACTTT CTTTTTTTTA CTTAAACCAC TCTGTGTCAC TGAGCTGATT TCACCTTTAG CCTGATAAAA TCATTGTCCT CTCCACCCTG ATTCCTACAG GAGACTACTC ACCCCATAAC CTCAAAAACC TCTTCATGAG GATGGTAAGT CACCTGAATC CTGAAGTGAA TTACTCGCTA TTCCATTGGA ACTCATATAG GACACCAGAA TCTAGACCTC CAGAGAACAG CAGGACCCAT CTTCAGAAAA TAAGAAGCAT TTGTTCCCTG AGCCTGTTGA ATCAAAGTGC AATTTCTATT CTTTTTGGAA TGTTAAAAAG TGAATCATAA TATTTAAGCA GGTGAACCCA CGAGTAACAT AGCAGGGTCT TTCTTGTCAT TATTAGCTCC AACCTAGCAC AGACATTAAA

GGTACAGATG TATACTAGCA TGAAACTGGG AGAACAGGAG CATTCGAGCA ACCTTGAGAC CAATGGGCCT CTCTTATAAA ATGCACACCT CCTCTCACTG AGATTGAGGA AGGTTTCTTG TCTCCGAGCC TTCTCCCAGT AGAGCTATAA ATCCAGGCTG GCTCCTCCCT CCCCACACAG CTGCTCCTGC TCTCCCTCCT CCAGGTGACC CCAGCCATGA GGACCCTCGC CATCCTTGCT GCCATTCTCC TGGTGGCCCT GCAGGCCCAG GCTGAGCCAC TCCAGGCAAG AGCTGATGAG GTTGCTGCAG CCCCGGAGCA GATTGCAGCG GACATCCCAG AAGTGGTTGT TTCCCTTGCA TGGGACGAAA GCTTGGCTCC AAAGCATCCA GGTGAGAGAG GCAGGCATGC AGAGCTGCTA AGTCTAGAGG GAAGGACGGG AGAGAGGTTC CAGAGTTGGG TCTCAGCAGT CTATGTCACT GAGGTGGCTT CACTTAGAAT CTCTGGGCAT TGATTTTCTC ATCTAGAAAT TGAACAGAGA

GCCAAATAAA CCTGAGAAAC TTTATTTCTC CAAAGACTTG ATTCCAAGAA ACATCTGTGA AATTCACTAA GTTTAAGATA TGAAGAGACA GACTAGTTAT TTCTGGATCT AAACAAGTAG ACTTAGTTGT AAAGAGAACA TTTTACTCTA TCTACAGAAG AGCTTTTAAA AACTGCAGCC AAGCCTGAGG GTAAGTTCAG GTGTGTGTGT GATGGGGCAG GAATGCAAAA ATGAGAGCAA AGGAGAATGA GTCTCAAATT CTGTGTGACA AGCACTGCTC TGCGTGTTTA TTCCTATCGA CTGAGGTTGT TCGTGCTACC GGCTGCAATG CAGCCAGCAT CACCTGTCAG CTAGCATGTG ACTTCCCCGA GATTCTTTTT CTTACCCACT GCTAACTCCA TACTCAATTT CTCATGCTCT CCCTGTCCCA GGCTCAAGGA AAAACATGGA CTGCTATTGC AGAATACCAG CGTGCATTGC AGGAGAACGT CGCTATGGAA CCTGCATCTA CCAGGGAAGA CTCTGGGCAT TCTGCTGCTG AGCTTGCAGA

AAAAGAAAAA TGAGCTCAAA ATTTGCTTTG AGAGCTACAG GGAATTGCTA TTACTCCTGT ACCTTCTGCT CAATTTCCTT TCCTCATCTC AAATAAATGC CTTGTTACAA GATTTCTGTG TTTCCACCTC TTTAATGTGT GATATGTGTC TGTGTCAAGA CACTTGGGAT ACACGTACCA AAACGCAAAA TCAAATTTTT GAACAATATA-3' (FRAG

NO ) (SEQ ID NO 11846)

5'-GGCBGCBBGG-3' (FRAG NO 1805) (SEQ ED NO 11187) 5'-GG CTG GOG-3' (FRAG NO 1806) (SEQ ID NO 11188)

5'-GGGGTCBCC-3' (FRAG NO 1807) (SEQ ID NO 11189) 5'-GGG TCC TCB TGG CTG GGGTC-3' (FRAG NO 1216) (SEQ DD NO 10594) 5'-CCT CTC TCC CGT CCT-3' (FRAG NO 1217) (SEQ ID NO 10595) 5'-CGCTGCBBTC TGCTCCGGGG CTGCBGCBBC CTCBTCBGCTC TTGCCTGGBGTG GCTCBGCCTGG GCCTGCBGGG CCBCCBGGBGB BTGGCBGCBBG GBTGGCGBGGG TCCTCBTGGC TGGGGTCBCCT GGBGGBGGGB GBGCBGG-3' (FRAG NO 180S) (SEQ ID NO 11190)

Human Macrophage Inflammatory Protein-1 -alpha RANTES Receptor Nucleic Acid and Antisense Oligonucleotide Fragments

5'-GTCTTTGTTT CTGGGCTCGT GCCCCBTCCC GGCTTCTCTC TGGTTCCGTC CTCTGTGGTG TTTGGCCCTG CTTCCTTTTG CCTGTTGAGG GGGCAGCAGT TGGGCCCCAA

AGGCCCTCTC GTTCACCTTC TGGCACGGAGTT GCATCCCCATA GTCAAACTCT GTGGTCGTGT CATAGTCCTC TGTGGTGTTT GGAGTTTCCA TCCCGGCTTC TCTCTGGTTC CAAGGGAGB GGGGGCBGCB GTTGGGCCCC BBBGGCCCTC TCGTTCBCCT TCTGGCBCGG BGTTGCBTCC CCBTBGTCBB BCTCTGTGGT CGTGTCBTBG

TCCTCTGTGG TGTTTGGBGT TTCCBTCCCG GCTTCTCTCT GGTTCCBBGG GB-3' (FRAG NO 1809) (SEQ ID NO 11191)

5'-GGGCC CC-3' (FRAG NO 1810) (SEQ ID NO 11192)

5'-GGGGGCBGC-3' (FRAG NO 1811) (SEQ ID NO 11193)

5'-CCCGGCTTC-3' (FRAG NO 1812) (SEQ ID NO 11194) 5'-GTC TTT GTT TCT GGG CTC GTG CC-3' (FRAG NO 1218) (SEQ DD NO 10596)

5'-CCB TCC CGG CTT CTC TCT GGT TCC-3' (FRAG NO 1219) (SEQ ID NO 10597)

5'-GTC CTCTGT GGT GTT TGG-3' (FRAG NO 1220) (SEQ ID NO 10598)

5'-CCC TGC TTC CTT TTG CCT GTT-3' (FRAG NO 1221) (SEQ ID NO 10599)

5'-GAGGGGGCAG CAGTTGGGCC CCAAAGGCCC TCTCGTTCAC CTTCTGGCAC GGAGTTGCAT CCCCATAGTC AAACTCTGTG GTCGT-3* (FRAG NO 1222) (SEQ ID NO 10600)

5'-GTCATAGTCCTCTGTGGTGTTTGGAGTTTCCATCCCGGCTTCTCTCTGGTTCCAAGGGA-3' (FRAGNO 1223)(SEQ ID NO 10601)

5'-GBGGGGGCBG CBGTTGGGCC CCBBBGGCCC TCTCGTTCBC CTTCTGGCBC GGBGTTGCBT CCCCBTBGTC BBBCTCTGTG GTCGTG-3' (FRAG NO 1224) (SEQ ID

NO 10602)

5'-TCBTBGTCCTCTGTGGTGTTTGGBGTTTCCBTCCCGGCTTCTCTCTGGTTCCBBGGGB-3'(FRAG NO 1225)(SEQ DDNO 10603) RANTES Antisense Oligonucleotide Fragments

5-GGGCBCGGGG CBGTGGGCGG GCBBTGTBGG CBBBGCBGCB GGGTGTGGTG TCCGBGGBBT BTGGGGBGGC BGBTGCBGGB GCGCBGBGGG CBGTBGCBBT

GBGGBTGBCB GCGBGGCGTG CCGCGGBGBC CTTCBTGGTB CCTGTGGBGB GGCTGTCGGB GGGGGTGTGG TGTCCGCTTG GCGGTTCTTT CGGGTGTTTC TTCTCTGGGT

TGGCCTGCTG CTCGTCGTGGT CGCTCCGCTC CCGGGTTCGT CTCGCTCTGT CGCCCCTTCC TTCCTTGTCG TGTTCCTCCC TTCCTTGCCT CT-3' (FRAG NO 1813) (SEQ ID

NO 11195) 5'-GGGTTGGC-3' (FRAG NO 1814) (SEQ DD NO 11196)

5'-CGGGG CBG-3' (FRAG NO 1815) (SEQ DD NO 11197)

5'-CCCGGGTTCG-3' (FRAG NO 1816) (SEQ ID NO 11198)

5'-GGGTGTGGTG-3' (FRAG NO 1817) (SEQ ID NO 11199)

5'-GGGCBCGGGG CBGTGGGCGG GCBBTGTBGG CBBBGCBGCB GGGTGTGGTG TCCGBGGBBT BTGGGGBGGC BGBTGCBGGB GCGC-3' (FRAG NO 1226) (SEQ ID NO 10604)

5'-BGBGGGCBGTB GCBBTGBGGB TGBCBGCGBG GCGTGCCGCG GBGBCCTTCB TGGTBCCTGT GGBGBGGCTG TCGGBGG-3' (FRAG NO 1227) (SEQ D O 10605)

5'-GGGTGTGGTGTCCGCTTGGCGGTTCTTTCGGGTGTTTCTTCTCTGGGTTGGCCTGCTGCTCGTCGTGGTC-3' (FRAG NO 1228) (SEQ ID NO 10606)

5'-GCTCCGCTCCCGGGTTCGTCTCGCTCTGTCGCCCCTTCCTTCCTTGTCGTGTTCCTCCCTTCCTTGCCTCT-3' (FRAG NO 1229) (SEQ ID NO 10607)

5'-GGGTGTGGTGTCCG-3' (FRAG NO 1230) (SEQ DD NO 10608) 5'-CTTGGCGGTTCTTTCGGGTG-3' (FRAG NO 1231) (SEQ ID NO 10609)

5'-TTTCTTCTCTGGGTTGGC-3' (FRAG NO 1232) (SEQ ID NO 10610)

5'-CTGCTGCTCGTCGTGGTC-3' (FRAG NO 1233) (SEQ ID NO 10611)

5'-GCTCCGCTCCCGGGTTC-3' (FRAG NO 1234) (SEQ ID NO 10612)

5'-GTCTCGCTCTGTCGCCC-3' (FRAG NO 1235) (SEQ ID NO 10613) 5'-CTTCCTTCCTTGTC-3' (FRAG NO 1236) (SEQ ID NO 10614)

5'-GTGTTCCTCCCTTCCTTGCCTCT-3' (FRAG NO 1237) (SEQ DD NO 10615)

5'-GGGCBCGGGG CBGTGGGCGG GCBBTGTBGG CBBBGCBGCB GGGTGTGGTG TCCGBGGBBT BTGGGGBGGC BGBTGCBGGB GCGCBGBGGG CBGTBGCBBT

GBGGBTGBCB GCGBGGCGTG CCGCGGBGBC CTTCBTGGTB CCTGTGGBGB GGCTGTCGGB GG-3' (FRAG NO 181 S) (SEQ ID NO 11200)

Human Muscarinic Acetylcholine Receptor HM1 Nucleic Acid and Antisense Oligonucleotide Fragments 5'-GCTGCCCGGC GGGGTGTGCG CTTGGCGCTC CCGTGCTCGG TTCTCTGTCT CCCGGTCCCC CTTGCCTGGC GTCTCGGGCC TTCGTCCTCT TCCTCTTCTT CCTTCCGCTC

CGTGGGGGCT GCTTGGTGGG GGCCTGTGCCT CGGGGTCCCG GGGCTTCTGG CCCTTGCCGT TCATGGTGGC TAGGTGGGGC GTTCBTGGTG GCTBGGTGGG GC-3'(FRAG

NO 1819)(SEQ DD NO 11201)

5'-GGTGGGGC-3' (FRAG NO 1820) (SEQ ID NO 11202)

5'-GCCCGGCGGGG-3' (FRAG NO 1821) (SEQ ID NO 11203) 5'-CGG GGC TTC TGG CCC-3' (FRAG NO 1822) (SEQ ID NO 11204)

5'-GTT CBT GGT GGC TBG GTG GGG C-3' (FRAG NO 1238) (SEQ ID NO 10616)

5'-GCT GCC CGG CGG GGT GTG CGC TTG GC-3' (FRAG NO 1239) (SEQ ID NO 10617)

5'-GCT CCC GTG CTC GGT TCT CTG TCT CCC GGT-3' (FRAG NO 1240) (SEQ DD NO 10618)

5'-CCC CCT TTG CCT GGC GTC TCG G-3' (FRAG NO 1241) (SEQ ID NO 10619) 5'-GCC TTC GTC CTC TTC CTC TTC TTC CTT CC-3' (FRAG NO 1242) (SEQ D O 10620)

5'-GCT CCG TGG GGG CTG CTT GGT GGG GGC CTG TGC CTC GGG GTC C-3' (FRAG NO 1243) (SEQ DD NO 10621)

S'-CGG GGC TTC TGG CCC TTG CC-3' (FRAG NO 1244) (SEQ ED NO 10622)

5'-GTT CAT GGT GGC TAG GTG GGG C-3' (FRAG NO 1245) (SEQ ID NO 10623)

Human Muscarinic Acetylcholine Receptor HM3 Nucleic Acid and Antisense Oligonucleotide Fragments 5'-GGG GTG GGT BGG CCG TGT CTG GGGGTT GGC CBT GTT GGT TGC CTCT TGG TGG TGC GCC GGG CGCG TCT TGG CTT TCT TCT CCT TCG GGC CCT CGG GCC GGT

GCT TGT GGGCT CCT CCC GGG CGG CCT CCC CGG GCG GGG GCT TCT TGGCG CTG GCG GGG GGG CCT CCTGCT CTG TGG CTG GGC GTT CCT TGG TGT TCT GGG TGGTGG CGG GCG TGG TGG CCT CTG TGGGGG CCC GCG GCT GCB GGG GTTG CCT GTC TGC TTC GTCCTT TGC GCT CCC GGG CCG CCGGG GTG GGT AGG CCG TGT CTG GGGGTT GGC CAT GTT GGT TGC CGGG CCC GCG GCT GCA GGG G-3' (FRAG NO 1823) (SEQ DD NO 11205) 5'-CCC GGG CGG-3' (FRAG NO 1824) (SEQ ID NO 11206)

5'-G GCG GGG GGG CC-3' (FRAG NO 1825) (SEQ DDNO 11207)

5'-CCC GGG CCG CC-3' (FRAG NO 1826) (SEQ ID NO 11208)

5'-GG CCG TGT-3' (FRAG NO 1827) (SEQ ID NO 11209) 5'-GGG GTG GGT BGG CCG TGT CTG GGG-3' (FRAG NO 1246) (SEQ DD NO 10624)

5'-GTT GGC CBT GTT GGT TGC C-3' (FRAG NO 1247) (SEQ ID NO 10625)

5'-TCT TGG TGG TGC GCC GGG C-3' (FRAG NO 1248) (SEQ DD NO 10626)

5'-GCG TCT TGG CTT TCT TCT CCT TCG GGC CCT CGG GCC GGT GCT TGT GG-3'(FRAGNO 1249)(SEQ ED NO 10627)

5'-GCT CCT CCC GGG CGG CCT CCC CGG GCG GGG GCT TCT TG-3' (FRAG NO 1250) (SEQ DD NO 10628) 5'-GCG CTG GCG GGG GGG CCT CCT CC-3' (FRAG NO 1251) (SEQ DD NO 10629)

5'-GCT CTG TGG CTG GGC GTT CCT TGGTGT TCT GGG TGG C-3' (FRAG NO 1252) (SEQ ID NO 10630)

5'-TGG CGG GCG TGG TGG CCT CTG TGG TGG-3' (FRAG NO 1253) (SEQ ID NO 10631)

5'-GGG CCC GCG GCT GCB GGG G-3' (FRAG NO 1254) (SEQ ID NO 10632)

5'-TTG CCT GTC TGC TTC GTC-3 ' (FRAG NO 1255) (SEQ DD NO 10633) 5'-CTT TGC GCT CCC GGG CCG CC-3' (FRAG NO 1256) (SEQ DD NO 10634)

5'-GGG GTG GGT AGG CCG TGT CTG GGG 3' (FRAG NO 1257) (SEQ DD NO 10635)

5'-GTT GGC CAT GTT GGT TGC C-3' (FRAG NO 1258) (SEQ DD NO 10636)

5'-GGG CCC GCG GCT GCA GGG G 3' (FRAG NO 1259) (SEQ DD NO 10637)

Human Fibronectin Antisense Oligonucleotide Fragments 5'-CGG TTT CCT TTG CGG TC TTG GCC CGG GCT CCG GGT G CCC GCC CGC CCG CCG GCC GCC GC CCC GCC GGG CTG TCC CCG CCC CGC CCC GGC CCG GGG CGC

GGG GG CGG CCC TCC CGC CCC TCT GG GCC GGC GCG GGC GTC GG CCG CTC GCG CCT GGG GTT CCC TCT CCT CCC CCT GTG C GCC TGC CTC TTG CTC TTCTGC

GTC CGC TGC CTT CTC CC CTC TCC TCG GCC GTT GCC TGT GC TGT CCG TCC TGT CGC CCT TCC GTG GTG C TGT TGT CTC TTC TGC CCT C GGT GTG CTG GTG CTG

GTG GTG GTG CCT CTG CCC GTG CTC GCCCTG CCT GGG CTG GCC TCT TCG GGT GTG GCT TTG GGG CTC TCT TGG TTG CCC TTT CTT CTC GTG GTG CCT CTC CTC

CCT GGC TTG GTC GT TGT CTG GGG TGG TGC TCC TCT CCC TTT CCC TGC TGG CCG TTT GT CCT GTT TTC TGT CTT CCT CT TTC CTC CTG TTT CTC CGT TTG GCT TGC TGC TTG CGG GGC TGT CTC C CTT GCC CCT GTG GGC TTT CCC TGG TCC GGT CTT CTC CTT GGG GGT C GCC CTT CTT GGT GGG CTGGCT CGT CTG TCT TTT

TCC TTC C TGG GGG TGG CCG TTG TGG GCG GTG TGG TCC GCC T TGC CTC TGC TGG TCT TTC-3' (FRAG NO 1828) (SEQ ED NO 11210)

5'-GGCCCGGGC-3' (FRAG NO 1829) (SEQ ID NO 11211)

5'-GCCGGCGCGGGCG-3' (FRAG NO 1830) (SEQ ID NO 11212)

5'-GCCTGGGCTGGCC-3' (FRAG NO 1831) (SEQ IDNO 11213) 5'-GGGGG TGGCCG-3' (FRAG NO 1832) (SEQ ID NO 11214)

5'-GG GGG TGG CCG TTG TGG GCG G-3' (FRAG NO 1833) (SEQ ID NO 11215)

5'-CGG TTT CCT TTG CGG TC-3' (FRAG NO 1260)(SEQ DD NO 10638)

5'-TTG GCC CGG GCT CCG GGT G-3' (FRAG NO 1261)(SEQ ID NO 10639)

5'-CCC GCC CGC CCG CCG GCC GCC GC-3' (FRAG NO 1262)(SEQ DD NO 10640) 5'-CCC GCC GGG CTG TCC CCG CCC CGC CCC-3' (FRAG NO 1263)(SEQ IDNO 10641)

5'-GGC CCG GGG CGC GGG GG-3' (FRAG NO 1264)(SEQ IDNO 10642)

5'-CGG CCC TCC CGC CCC TCT GG-3' (FRAG NO 1265)(SEQ ID NO 10643)

5'-GCC GGC GCG GGC GTC GG-3' (FRAG NO 1266)(SEQ DD NO 10644)

5'-CCG CTC GCG CCT GGG GTT CCC TCT CCT CCC CCT GTG C-3' (FRAG NO 1267)(SEQ ID NO 10645) 5'-GCC TGC CTC TTG CTC TTC-3' (FRAG NO 1268)(SEQ ID NO 10646)

5'-TGC GTC CGC TGC CTT CTC CC-3' (FRAG NO 1269)(SEQ ID NO 10647)

5'CTC TCC TCG GCC GTT GCC TGT GC-3' (FRAG NO 1270)(SEQ DD NO 10648)

5'-TGT CCG TCC TGT CGC CCT TCC GTG GTG C-3' (FRAG NO 1271)(SEQ ID NO 10649)

5'-TGT TGT CTC TTC TGC CCT C-3' (FRAG NO 1272)(SEQ ID NO 10650) 5'-GGT GTG CTG GTG CTG GTG GTG GTG-3' (FRAG NO 1273)(SEQ ID NO 10651)

5'-CCT CTG CCC GTG CTC GCC-3' (FRAG NO 1274)(SEQ DD NO 10652)

5'-CTG CCT GGG CTG GCC TCT TCG GGT-3' (FRAG NO 1275)(SEQ ID NO 10653)

5'-GTG GCT TTG GGG CTC TCT TGG TTG CCC TTT-3' (FRAG NO 1276)(SEQ ID NO 10654)

5'-CTT CTC GTG GTG CCT CTC CTC CCT GGC TTG GTC GT-3' (FRAG NO 1277)(SEQ ID NO 10655) 5'- TGT CTG GGG TGG TGC TCC TCT CCC-3' (FRAG NO 1278)(SEQ ID NO 10656)

5'-TTT CCC TGC TGG CCG TTT GT-3' (FRAG NO 1279)(SEQ ID NO 10657)

5'-CCT GTT TTC TGT CTT CCT CT-3' (FRAG NO 1280)(SEQ ID NO 10658)

5'-TTC CTC CTG TTT CTC CGT-3' (FRAG NO 1281)(SEQ ID NO 10659)

5'-TTG GCT TGC TGC TTG CGG GGC TGT CTC C-3' (FRAG NO 1282)(SEQ ID NO 10660) 5'-CTT GCC CCT GTG GGC TTT CCC-3' (FRAG NO 1283)(SEQ ID NO 10661)

5'-TGG TCC GGT CTT CTC CTT GGG GGT C-3' (FRAG NO 1284)(SEQ DD NO 10662)

5'-GCC CTT CTT GGT GGG CTG-3' (FRAG NO 1285)(SEQ ID NO 10663)

S'-GCT CGT CTG TCT TTT TCC TTC C-3' (FRAG NO 1286)(SEQ ID NO 10664)

S'-TGG GGG TGG CCG TTG TGG GCG GTG TGG TCC GCC T-3' (FRAG NO 1287)(SEQ ID NO 10665) 5'-TGC CTC TGC TGG TCT TTC-3' (FRAG NO 1288)(SEQ ID NO 10666)

Human Interleukin-1 (IL-1) Nucleic Acid and antisense Oligocnucleotide Fragments

5'-AAGCTTCTAC CCTAGTCTGG TGCTACACTT ACATTGCTTA CATCCAAGTG TGGTTATTTC TGTGGCTCCT GTTATAACTA TTATAGCACC AGGTCTATGA CCAGGAGAAT TAGACTGGCA TTAAATCAGA ATAAGAGATT TTGCACCTGC AATAGACCTT ATGACACCTA ACCAACCCCA TTATTTACAA TTAAACAGGA ACAGAGGGAA TACTTTATCC AACTCACACA AGCTGTTTTC CTCCCAGATC CATGCTTTTT TGCGTTTATT ATTTTTTAGA GATGGGGGCT TCACTATGTT GCCCACACTG GACTAAAACT CTGGGCCTCA AGTGATTGTC CTGCCTCAGC CTCCTGAATA GCTGGGACTA CAGGGGCATG CCATCACACC TAGTTCATTT CCTCTATTTA AAATATACAT GGCTTAAACT CCAACTGGGA

ACCCAAAACA TTCATTTGCT AAGAGTCTGG TGTTCTACCA CCTGAACTAG GCTGGCCACA GGAATTATAA AAGCTGAGAA ATTCTTTAAT AATAGTAACC AGGCAACATC ATTGAAGGCT CATATGTAAA AATCCATGCC TTCCTTTCTC CCAATCTCCA TTCCCAAACT TAGCCACTGG TTCTGGCTGA GGCCTTACGC ATACCTCCCG GGGCTTGCAC ACACCTTCTT CTACAGAAGA CACACCTTGG GCATATCCTA CAGAAGACCA GGCTTCTCTC TGGTCCTTGG TAGAGGGCTA CTTTACTGTA ACAGGGCCAG GGTGGAGAGT TCTCTCCTGA AGCTCCATCC CCTCTATAGG AAATGTGTTG ACAATATTCA GAAGAGTAAG AGGATCAAGA CTTCTTTGTG CTCAAATACC ACTGTTCTCT TCTCTACCCT GCCCTAACCA GGAGCTTGTC ACCCCAAACT CTGAGGTGAT TTATGCCTTA ATCAAGCAAA CTTCCCTCTT CAGAAAAGAT GGCTCATTTT CCCTCAAAAG TTGCCAGGAG

CTGCCAAGTA TTCTGCCAAT TCACCCTGGA GCACAATCAA CAAATTCAGC CAGAACACAA CTACAGCTAC TATTAGAACT ATTATTATTA ATAAATTCCT CTCCAAATCT AGCCCCTTGA CTTCGGATTT CACGATTTCT CCCTTCCTCC TAGAAACTTG ATAAGTTTCC CGCGCTTCCC TTTTTCTAAG ACTACATGTT TGTCATCTTA TAAAGCAAAG GGGTGAATAA ATGAACCAAA TCAATAACTT CTGGAATATC TGCAAACAAC AATAATATCA GCTATGCCAT CTTTCACTAT TTTAGCCAGT ATCGAGTTGA ATGAACATAG AAAAATACAA AACTGAATTC TTCCCTGTAA ATTCCCCGTT TTGACGACGC ACTTGTAGCC ACGTAGCCAC GCCTACTTAA GACAATTACA AAAGGCGAAG AAGACTGACT CAGGCTTAAG CTGCCAGCCA GAGAGGGAGT CATTTCATTG GCGTTTGAGT CAGCAAAGGT ATTGTCCTCA CATCTCTGGC TATTAAAGTA TTTTCTGTTG TTGTTTTTCT

CTTTGGCTGT TTTCTCTCAC ATTGCCTTCT CTAAAGCTAC AGTCTCTCCT TTCTTTTCTT GTCCCTCCCT GGTTTGGTAT GTGACCTAGA ATTACAGTCA GATTTCAGAA AATGATTCTC TCATTTTGCT GATAAGGACT GATTCGTTTT ACTGAGGGAC GGCAGAACTA GTTTCCTATG AGGGCATGGG TGAATACAAC TGAGGCTTCT CATGGGAGGG AATCTCTACT ATCCAAAATT ATTAGGAGAA AATTGAAAAT TTCCAACTCT GTCTCTCTCT TACCTCTGTG TAAGGCAAAT ACCTTATTCT TGTGGTGTTT TTGTAACCTC TTCAAACTTT CATTGATTGA ATGCCTGTTC TGGCAATACA TTAGGTTGGG CACATAAGGA ATACCAACAT AAATAAAACA TTCTAAAAGA AGTTTACGAT CTAATAAAGG AGACAGGTAC ATAGCAAACT AATTCAAAGG AGCTAGAAGA TGGAGAAAAT GCTGAATGTG GACTAAGTCA TTCAACAAAG TTTTCAGGAA GCACAAAGAG

GAGGGGCTCC CCTCACAGAT ATCTGGATTA GAGGCTGGCT GAGCTGATGG TGGCTGGTGT TCTCTGTTGC AGAAGTCAAG ATGGCCAAAG TTCCAGACAT GTTTGAAGAC CTGAAGAACT GTTACAGGTA AGGAATAAGA TTTATCTCTT GTGATTTAAT GAGGGTTTCA AGGCTCACCA GAATCCAGCT AGGCATAACA GTGGCCAGCA TGGGGGCAGG CCGGCAGAGG TTGTAGAGAT GTGTACTAGT CCTGAAGTCA GAGCAGGTTC AGAGAAGACC CAGAAAAACT AAGCATTCAG CATGTTAAAC TGAGATTACA TTGGCAGGGA GACCGCCATT TTAGAAAAAT TATTTTTGAG GTCTGCTGAG CCCTACATGA ATATCAGCAT CAACTTAGAC ACAGCCTCTG TTGAGATCAC ATGCCCTGAT ATAAGAATGG GTTTTACTGG TCCATTCTCA GGAAAACTTG ATCTCATTCA GGAACAGGAA ATGGCTCCAC AGCAAGCTGG GCATGTGAAC TCACATATGC AGGCAAATCT CACTCAGATG

TAGAAGAAAG GTAAATGAAC ACAAAGATAA AATTACGGAA CATATTAAAC TAACATGATG TTTCCATTAT CTGTAGTAAA TACTAACACA AACTAGGCTG TCAAAATTTT GCCTGGATAT TTTACTAAGT ATAAATTATG AAATCTGTTT TAGTGAATAC ATGAAAGTAA TGTGTAACAT ATAATCTATT TGGTTAAAAT AAAAAGGAAG TGCTTCAAAA CCTTTCTTTT CTCTAAAGGA GCTTAACATT CTTCCCTGAA CTTCAATTAA AGCTCTTCAA TTTGTTAGCC AAGTCCAATT TTTACAGATA AAGCACAGGT AAAGCTCAAA GCCTGTCTTG ATGACTACTA ATTCCAGATT AGTAAGATAT GAATTACTCT ACCTATGTGT ATGTGTAGAA GTCCTTAAAT TTCAAAGATG ACAGTAATGG CCATGTGTAT GTGTGTGACC CACAACTATC ATGGTCATTA AAGTACATTG GCCAGAGACC ACATGAAATA ACAACAATTA CATTCTCATC ATCTTATTTT GACAGTGAAA ATGAAGAAGA

CAGTTCCTCC ATTGATCATC TGTCTCTGAA TCAGGTAAGC AAATGACTGT AATTCTCATG GGACTGCTAT TCTTACACAG TGGTTTCTTC ATCCAAAGAG AACAGCAATG ACTTGAATCT TAAATACTTT TGTTTTACCC TCACTAGAGA TCCAGAGACC TGTCTTTCAT TATAAGTGAG ACCAGCTGCC TCTCTAAACT AATAGTTGAT GTGCATTGGC TTCTCCCAGA ACAGAGCAGA ACTATCCCAA ATCCCTGAGA ACTGGAGTCT CCTGGGGCAG GCTTCATCAG GATGTTAGTT ATGCCATCCT GAGAAAGCCC CGCAGGCCGC TTCACCAGGT GTCTGTCTCC TAACGTGATG TGTTGTGGTT GTCTTCTCTG ACACCAGCAT CAGAGGTTAG AGAAAGTCTC CAAACATGAA GCTGAGAGAG AGGAAGCAAG CCAGCTGAAA GTGAGAAGTC TACAGCCACT CATCAATCTG TGTTATTGTG TTTGGAGACC ACAAATAGAC ACTATAAGTA CTGCCTAGTA TGTCTTCAGT ACTGGCTTTA

AAAGCTGTCC CCAAAGGAGT ATTTCTAAAA TATTTTGAGC ATTGTTAAGC AGATTTTTAA CCTCCTGAGA GGGAACTAAT TGGAAAGCTA CCACTCACTA CAATCATTGT TAACCTATTT AGTTACAACA TCTCATTTTT GAGCATGCAA ATAAATGAAA AAGTCTTCCT AAAAAAATCA TCTTTTTATC CTGGAAGGAG GAAGGAAGGT GAGACAAAAG GGAGAGAGGG AGGGAAGCCT AATGAAACAC CAGTTACCTA AGACCAGAAT GGAGATCCTC CTCACTACCT CTGTTGAATA CAGCACCTAC TGAAAGAACT TTCATTCCCT GACCATGAAC AGCCTCTCAG CTTCTGTTTT CCTTCCTCAC AGAAATCCTT CTATCATGTA AGCTATGGCC CACTCCATGA AGGCTGCATG GATCAATCTG TGTCTCTGAG TATCTCTGAA ACCTCTAAAA CATCCAAGCT TACCTTCAAG GAGAGCATGG TGGTAGTAGC AACCAACGGG AAGGTTCTGA AGAAGAGACG GTTGAGTTTA AGCCAATCCA TCACTGATGA TGACCTGGAG GCCATCGCCA ATGACTCAGA GGAAGGTAAG GGGTCAAGCA CAATAATATC TTTCTTTTAC AGTTTTAAGC AAGTAGGGAC AGTAGAATTT AGGGGAAAAT TAAACGTGGA GTCAGAATAA CAAGAAGACA ACCAAGCATT AGTCTGGTAA CTATACAGAG GAAAATTAAT TTTTATCCTT CTCCAGGAGG GAGAAATGAG CAGTGGCCTG AATCGAGAAT ACTTGCTCAC AGCCATTATT TCTTAGCCAT ATTGTAAAGG TCGTGTGACT TTTAGCCTTT CAGGAGAAAG CAGTAATAAG ACCACTTACG AGCTATGTTC CTCTCATACT AACTATGCCT CCTTGGTCAT GTTACATAAT CTTTTCGTGA TTCAGTTTCC TCTACTGTAA AATGGAGATA ATCAGAATCC CCCACTCATT

GGATTGTTGT AAAGATTAAG AGTCTCAGGC TTTACAGACT GAGCTAGCTG GGCCCTCCTG ACTGTTATAA AGATTAAATG AGTCAACATC CCCTAACTTC TGGACTAGAA TAATGTCTGG TACAAAGTAA GCACCCAATA AATGTTAGCT ATTACTATCA TTATTATTAT TATTTTATTT TTTTTTTTTG AGATGGAGTC TGGCTCTGTC ACCCAGGCTG GAGTGCAGTG GCACAATCTC GGCTCACTGC AAGCTCTGCC TCCTGGGTTC ATGCCATTCT CCTGCCTCAG CCTCCCGAGT AAGCTGGGAA TACAGGCACC CGCCACTGTT CCCGGCTAAT TTTTTGTATT TTTAGTAGAG ACGGAGTTTC ACCGTGGTCT CCATCTCCTC GTGATCCACC CACCTTGGCC TCCCAAAGTG CCGGGATTAC AGGCGTGAGC CACCGCGCCC GGCCTATTAT TATTATTATT ACTACTACTA CTACCTATAT GAATACTACC AGCAATACTA ATTTATTAAT GACTGGATTA TGTCTAAACC TCACAAGAAT

CCTACCTTCT CATTTTACAT AAAAGGAAAC TAAGCTCATT GAGATAGGTA AACTGCCCAA TGGCATACAT CTGTAAGTGG GAGAGCCTCA AATCTAATTC AGTTCTACCT GAGTAAAAAA ATCATGGTTT CTCCTCCATC CCTTTACTGT ACAAGCCTCC ACATGAACTA TAAACCCAAT ATTCCTGTTT TTAAGATAAT ACCTAAGCAA TAACGCATGT TCACCTAGAA GGTTTTAAAA TGTAACAAAA TATAAGAAAA TAAAAATCAC TCATATCGTC AGTGAGAGTT TACTACTGCC AGCACTATGG TATGTTTCCT TAAAATCTTT GCTATACACA TACCTACATG TGAACAAATA TGTCTAACAT CAAGACCACA CTATTTACAA CTTTATATCC AGCTTTTCTT ACTTAGCAAT GTATTGAGGA CATTTTAGAG TGCCCGTTTT TCACCATTAT AAGCAATGCA ACAATGAACA TCTGTATAAA TAAATATTCA TTTCTCTCAC CCTTTATTTC CTTAGAATAT ATTCCTAGAA GTAGAATTTC

CCAGAGCCAT GAGGATTTGT GACGCTATTG ATATGTGCCA CTTTGCACTC TCTGTGACAT ATATAATTAT TTTTAATGCA TTCATTTTTT TCTCAGAGTG CATTCGTTTG AAAACATAGA CGGGAAATAC TGGTAGTCTT CCTTGTCAGT TAGAAACACC CAAACAATGA AAAATGAAAA AGTTGCACAA ATAGTCTCTA AAAACAATGA AACTATTGCC TGAGGAATTG AAGTTTAAAA AGAAGCACAT AAGCAACAAC AAGGATAATC CTAGAAAACC AGTTCTGCTG ACTGGGTGAT TTCACTTCTC TTTGCTTCCT CATCTGGATT GGAATATTCC TAATACCCCC TCCAGAACTA TTTTCCCTGT TTGTACTAGA CTGTGTATAT CATCTGTGTT TGTACATAGA CATTAATCTG CACTTGTGAT CATGGTTTTA GAAATCATCA AGCCTAGGTC ATCACCTTTT AGCTTCCTGA GCAATGTGAA ATACAACTTT ATGAGGATCA TCAAATACGA ATTCATCCTG AATGACGCCC TCAATCAAAG

TATAATTCGA GCCAATGATC AGTACCTCAC GGCTGCTGCA TTACATAATC TGGATGAAGC AGGTACATTA AAATGGCACC AGACATTTCT GTCATCCTCC CCTCCTTTCA TTTACTTATT TATTTATTTC AATCTTTCTG CTTGCAAAAA ACATACCTCT TCAGAGTTCT GGGTTGCACA ATTCTTCCAG AATAGCTTGA AGCACAGCAC CCCCATAAAA ATCCCAAGCC AGGGCAGAAG GTTCAACTAA ATCTGGAAGT TCCACAAGAG AGAAGTTTCC TATCTTTGAG AGTAAAGGGT TGTGCACAAA GCTAGCTGAT GTACTACCTC TTTGGTTCTT TCAGACATTC TTACCCTCAA TTTTAAAACT GAGGAAACTG TCAGACATAT TAAATGATTT ACTCAGATTT ACCCAGAAGC CAATGAAGAA CAATCACTCT CCTTTAAAAA GTCTGTTGAT CAAACTCACA AGTAAGACCA AACCAGGAAG ATCTTTATTA TCTCTGATAA CATATTTGTG AGGCAAAACC TCCAATAAGC TACAAATATG

GCTTAAAGGA TGAAGTTTAG TGTCCAAAAA CTTTTATCAC ACACATCCAA TTTTCATGGC GGACATGTTT TAGTTTCAAC AGTATACATA TTTTCAAAGG TCCAGAGAGG CAATTTTGCA ATAAACAAGC AAGACTTTTT CTGATTGGAT GCACTTCAGC TAACATGCTT TCAACTCTAC ATTTACAAAT TATTTTGTGT TCTATTTTTC TACTTAATAT TATTTCTGCA ATTTTCCCAA TATTGACATC GTGTATGTAT TTGCCATTTT TAATATCACT AGACAATTCA ATCAGGTTGC TACGTTGGTC CCTTGGGTTT ACTCTAAATA GCTTGATTGC AAATATCTTT GTATATATTA TTGTTTTTTC TCCTATCTTG TAATTTCTTT GAGCACATCC CAAAGAGGAA TGCCTAGATC AATGGGCACA AATAATTTGA CAGCTCTTAT TAAACATTAT TCTGTAAGTA AAAACTGAAC TACTTTTCAG TATCACTAGC AACATATGAG TGTATCAGCT TCCTAAACCC CTCCATGTTA GGTCATTATG

AACTTATGAT CTAACAAATT ACAGGGTCTT ATCCCACTAA TGAAATTATA AGAGATTCAA CACTTATTCA GCCCCGAAGG ATTCATTCAA CGTAGAAAAT TCTAAGAACA TACACCATAG GTGGGGACCT

AACTACACAC ACACACACAC ACACACACAC ACACACACAC ACCATGCACA CACAATCTAC ATCAACACTT GATTTTATAC AAATACAATG AATTTACTTT CTTTTTGGTT CTTCTCTTCA CCAGTGAAAT TTGACATGGG TGCTTATAAG TCATCAAAGG ATGATGCTAA AATTACCGTG ATTCTAAGAA TCTCAAAAAC TCAATTGTAT GTGACTGCCC AAGATGAAGA CCAACCAGTG CTGCTGAAGG TCAGTTGTCC TTTGTCTCCA ACTTACCTTC ATTTACATCT CATATGTTTG TAAATAAGCC CAATAGGCAG ACACCTCTAA

CAAGGTGACA CTGTCCTCTT TCCTTCCTAC CACAGCCCCC ACCTACCCAC CCCACTCCCA TTGATTCCAG AGGCGTGCCT AGGCAGGATC TATGAGAAAA TATAACAGAG AGTAAGAGGA AAATTACCTT CTTTCTTTTT CCTTTCCCTG CCTGACCTTA TTCACCTCCC ATCCCAGAGC ATCCATTTAT TCCATTGATC TTTACTGACA TCTATTATCT GACCTACACA ATACTAGACA TTAGGACAAT GTGGCCTGCC TCCAAGAAAC TCAAATAAGC CAACTGAGAT CAGAGAGGAT TAATCACCTG CCAATGGGCA CAAAGCAACA AGCTGGGAGC CAAGTCCCAA AATGGGGCCT GCTGCTTCCA GTTCCCCTCT CTCTGCATTG ATGTCAGCAT TATCCTTCGT CCCAGTCCTG TCTCCACTAC CACTTTCCCC CTCAAACACA CACACACACA ACAGCCTTAG ATGTTTTCTC CACTGATAAG TAGGTGACTC AATTTGTAAG TATATAATCC AAGACCTTCT ATTCCCAAGT AGAATTTATG

TGCCTGCCTG TGCTTTTCTA CCTGGATCAA GTGATGTCTA CAGAGTAGGG CAGTAGCTTC ATTCATGAAC TCATTCAACA AGCATTATTC ACTGAGAGCC TTGTATTTTT CAGGCATAGT GCCAACAGCA GTGTGGACAG TGGTGCATCA AAGCCTCTAG TCTCATAGAA CTTAGTCTTC TGGAGGATAT GGAAAACAGA CAACCCAAAC AACCAACAAA AGAGCAAGAT GCTGCAAAAA AAAAAAAAAT GAATAGGGTG CTAAGATAGA GAAAAGTGGG AGAGTGCTAT TTAGACAAAG TGGTAAAAAC AAAGCCCCTT GTGAGATGAG AGCTGCCGAC AGAGGGGGCG GGTCATGGTT GTGGGTTTTT GGGTAGGACA TTCAGAGGAG GGGGCGGGTC GTGGTTGTGG GTTTTTGGGT AGGACATTCA GAGGAGGGGG CGGGTCGTGG TTGTGGGTTT TTGGGTAGGA CATTCAGAGG AGGGGGCGGG TCGTGGTTGT GGGTTTTTGG GTAGGACATT

CAGAGGAGGG GGCGGGTCGT GGTTGTGGGT TTTTGGGACA TTCAGAGGAG TCTGAATGCA CCCAGGCCTA CAACTTCAAG ATGGTAAAGG ACAGCTCCAA GGATCAGAAG AAGCATTCTT GGAACTGGGG CATTTTGAGA AGGAGGAAAA ATATGCAGAG ACTAGTGCTT GCAGAGCTTG CATTTGGATT TCATTTGAGG TACAATGAAA ACCCATTAAT GGGTTTCACA CAGTGCAATG GCCTGACCTC ACTTATATTT CCTAAAATAG AAAACAGATC AGAAGGAAGG CAATAGAGAA GCAGAAAGTC CAATGAGGAG GTTTCACAGC AGTCATGGGG GTGGGGTAAG GAAAAGAAGT GGAAAGAAAC AGACAGAATT GGGTTATATT TTGGAGATAG AACCAACAGA AGGAAGAGGA GAAACAACAT TTACTGAGAA GGGAAAAAGT AGGAGAGGAA TAGGTTTGGG AAATAAATCC TGCTGACATT GGAAACCCCA AGGAAGCCTC AAAAGTATAT TTACTTGCTT

TAGATTTAAA AGAATAGGAA AGAAGCATCT CAACTTGGAA TTTGAAATCT ATTTTTCCAT AAAAGTATTG TTAAATTCTA CTCATACTCA CAAGAAAAGT ACATTCTAAA GAGTATATTG AAAGAGTTTA CTGATATACT TAGGAATTTT GTGTGTATGT GTGTGTGTGT ATGTGTGTGT GTGTGTTTAA CCTTCAATTG TTGACTTAAA TACTGAGATA AATGTCATCT AAATGCTAAA TTGATTTCCC AAAGGTATGA TTTGTTCACT TGGAGATCAA AATGTTTAGG GGGCTTAGAA TCACTGTAGT GCTCAGATTT GATGCAAAAT GTCTTAGGCC TATGTTGAAG GCAGGACAGA AACAATGTTT CCCTCCTACC TGCCTGGATA CAGTAAGATA CTAGTGTCAC TGACAATCTT CATAACTAAT TTAGATCTCT CTCCAATCAA CTAAGGAAAT CAACTCTTAT TAATAGACTG GGCCACACAT CTACTAGGCA TGTAATAAAT GCTTGCTGAA TGAACAAATG AATGAAGAGC CTATAGCATC

ATGTTACAGC CATAGTCCTA AAGTGGTGTT TCTCATGAAG GCCAAATGCT AAGGGATTGA GCTTCAGTCC TTTTTCTAAC ATCTTGTTCT CTAACAGAAT TCTCTTCTTT TCTTCATAGG AGATGCCTGA GATACCCAAA ACCATCACAG GTAGTGAGAC CAACCTCCTC TTCTTCTGGG AAACTCACGG CACTAAGAAC TATTTCACAT CAGTTGCCCA TCCAAACTTG TTTATTGCCA CAAAGCAAGA CTACTGGGTG TGCTTGGCAG GGGGGCCACC CTCTATCACT GACTTTCAGA TACTGGAAAA CCAGGCGTAG GTCTGGAGTC TCACTTGTCT CACTTGTGCA GTGTTGACAG TTCATATGTA CCATGTACAT GAAGAAGCTA AATCCTTTAC TGTTAGTCAT TTGCTGAGCA TGTACTGAGC CTTGTAATTC TAAATGAATG TTTACACTCT TTGTAAGAGT GGAACCAACA CTAACATATA ATGTTGTTAT TTAAAGAACA CCCTATATTT TGCATAGTAC CAATCATTTT AATTATTATT

CTTCATAACA ATTTTAGGAG GACCAGAGCT ACTGACTATG GCTACCAAAA AGACTCTACC CATATTACAG ATGGGCAAAT TAAGGCATAA GAAAACTAAG AAATATGCAC AATAGCAGTT GAAACAAGAA GCCACAGACC TAGGATTTCA TGATTTCATT TCAACTGTTT GCCTTCTGCT TTTAAGTTGC TGATGAACTC TTAATCAAAT AGCATAAGTT TCTGGGACCT CAGTTTTATC ATTTTCAAAA TGGAGGGAAT AATACCTAAG CCTTCCTGCC GCAACAGTTT TTTATGCTAA TCAGGGAGGT CATTTTGGTA AAATACTTCT CGAAGCCGAG CCTCAAGATG AAGGCAAAGC ACGAAATGTT ATTTTTTAAT TATTATTTAT ATATGTATTT ATAAATATAT TTAAGATAAT TATAATATAC TATATTTATG GGAACCCCTT CATCCTCTGA GTGTGACCAG GCATCCTCCA CAATAGCAGA CAGTGTTTTC TGGGATAAGT AAGTTTGATT TCATTAATAC AGGGCATTTT GGTCCAAGTT

GTGCTTATCC CATAGCCAGG AAACTCTGCA TTCTAGTACT TGGGAGACCT GTAATCATAT AATAAATGTA CATTAATTAC CTTGAGCCAG TAATTGGTCC GATCTTTGAC TCTTTTGCCA TTAAACTTAC CTGGGCATTC TTGTTTCATT CAATTCCACC TGCAATCAAG TCCTACAAGC TAAAATTAGA TGAACTCAAC TTTGACAACC ATGAGACCAC TGTTATCAAA ACTTTCTTTT CTGGAATGTA ATCAATGTTT CTTCTAGGTT CTAAAAATTG TGATCAGACC ATAATGTTAC ATTATTATCA ACAATAGTGA TTGATAGAGT GTTATCAGTC ATAACTAAAT AAAGCTTGCA ACAAAATTCT CTGACACATA GTTATTCATT GCCTTAATCA TTATTTTACT GCATGGTAAT TAGGGACAAA TGGTAAATGT TTACATAAAT AATTGTATTT AGTGTTACTT TATAAAATCA AACCAAGATT TTATATTTTT TTCTCCTCTT TGTTAGCTGC CAGTATGCAT AAATGGCATT AAGAATGATA

ATATTTCCGG GTTCACTTAA AGCTCATATT ACACATACAC AAAACATGTG TTCCCATCTT TATACAAACT CACACATACA GAGCTACATT AAAAACAACT AATAGGCCAG GCACGGTGGC TCAGACCTGT AATCCCAGCA CTTTGGGAGG ACCAACCTCT TCGAGGCACA AGGCACAACA GGCTGCTGTG GGATTCTCTT CAGCCAATCT TCATTGCTCA AGTGTCTGAA GCAGCCATGG CAGAAGTACC TGAGCTCGCC AGTGAAATGA TGGCTTATTA CAGTGGCAAT GAGGATGACT TGTTCTTTGA AGCTGATGGC CCTAAACAGA TGAAGTGCTC CTTCCAGGAC CTGGACCTCT GCCCTCTGGA TGGCGGCATC CAGCTACGAA TCTCCGACCA CCACTACAGC AAGGGCTTCA GGCAGGCCGC GTCAGTTGTT GTGGCCATGG ACAAGCTGAG GAAGATGCTG GTTCCCTGCC CACAGACCTT CCAGGAGAAT GACCTGAGCA CCTTCTTTCC CTTCATCTTT GAAGAAGAAC CTATCTTCTT

CGACACATGG GATAACGAGG CTTATGTGCA CGATGCACCT GTACGATCAC TGAACTGCAC GCTCCGGGAC TCACAGCAAA AAAGCTTGGT GATGTCTGGT CCATATGAAC TGAAAGCTCT CCACCTCCAG GGACAGGATA TGGAGCAACA AGTGGTGTTC TCCATGTCCT TTGTACAAGG AGAAGAAAGT AATGACAAAA TACCTGTGGC CTTGGGCCTC AAGGAAAAGA ATCTGTACCT GTCCTGCGTG TTGAAAGATG ATAAGCCCAC TCTACAGCTG GAGAGTGTAG ATCCCAAAAA TTACCCAAAG AAGAAGATGG AAAAGCGATT TGTCTTCAAC AAGATAGAAA TCAATAACAA GCTGGAATTT GAGTCTGCCC AGTTCCCCAA CTGGTACATC AGCACCTCTC AAGCAGAAAA CATGCCCGTC TTCCTGGGAG GGACCAAAGG CGGCCAGGAT ATAACTGACT TCACCATGCA ATTTGTGTCT TCCTAAAGAG AGCTGTACCC AGAGAGTCCT GTGCTGAATG TGGACTCAAT CCCTAGGGCT

GGCAGAAAGG GAACAGAAAG GTTTTTGAGT ACGGCTATAG CCTGGACTTT CCTGTTGTCT ACACCAATGC CCAACTGCCT GCCTTAGGGT AGTGCTAAGA GGATCTCCTG TCCATCAGCC AGGACAGTCA GCTCTCTCCT TTCAGGGCCA ATCCCCAGCC CTTTTGTTGA GCCAGGCCTC TCTCACCTCT CCTACTCACT TAAAGCCCGC CTGACAGAAA CCACGGCCAC ATTTGGTTCT AAGAAACCCT CTGTCATTCG CTCCCACATT CTGATGAGCA ACCGCTTCCC TATTTATTTA TTTATTTGTT TGTTTGTTTT ATTCATTGGT CTAATTTATT CAAAGGGGGC AAGAAGTAGC AGTGTCTGTA AAAGAGCCTA GTTTTTAATA GCTATGGAAT CAATTCAATT TGGACTGGTG TGCTCTCTTT AAATCAAGTC CTTTAATTAA GACTGAAAAT ATATAAGCTC AGATTATTTA AATGGGAATA TTTATAAATG AGCAAATATC ATACTGTTCA ATGGTTCTGA AATAAACTTC TCTGAAG

AGAAAGAAAG AGAGAGAGAA AGAAAAGAAA GAGGAAGGAA GGAAGGAAGG AAGAAAGACA GGCTCTGAGG AAGGTGGCAG TTCCTACAAC GGGAGAACCA GTGGTTAATT TGCAAAGTGG ATCCTGTGGA GGCANNCAGA GGAGTCCCCT AGGCCACCCA GACAGGGCTT TTAGCTATCT GCAGGCCAGA CACCAAATTT CAGGAGGGCT CAGTGTTAGG AATGGATTAT GGCTTATCAA ATTCACAGGA AACTAACATG TTGAACAGCT TTTAGATTTC CTGTGGAAAA TATAACTTAC TAAAGATGGA GTTCTTGTGA CTGACTCCTG ATATCAAGAT ACTGGGAGCC AAATTAAAAA TCAGAAGGCT GCTTGGAGAG CAAGTCCATG AAATGCTCTT TTTCCCACAG TAGAACCTAT TTCCCTCGTG TCTCAAATAC TTGCACAGAG GCTCACTCCC TTGGATAATG CAGAGCGAGC ACGATACCTG GCACATACTA ATTTGAATAA AATGCTGTCA AATTCCCATT CACCCATTCA

AGCAGCAAAC TCTATCTCAC CTGAATGTAC ATGCCAGGCA CTGTGCTAGA CTTGGCTCAA AAAGATTTCA GTTTCCTGGA GGAACCAGGA GGGCAAGGTT TCAACTCAGT GCTATAAGAA GTGTTACAGG CTGGACACGG TGGCTCACGC CTGTAATCCC AACATTTGGG AGGCCGAGGC GGGCAGATCA CAAGGTCAGG AGATCGAGAC CATCCTGGCT AACATGGTGA AACCCTGTCT CTACTAAAAA TACAAAAAAT TAGCCGGGCG TTGGCGGCAG GTGCCTGTAG TCCCAGCTGC TGGGGAGGCT GAGGCAGGAG AATGGTGTGA ACCCGGGAGG CGGAACTTGC AGGGGGCCGA GATCGTGCCA CTGCACTCCA GCCTGGGCGA CAGAGTGAGA CTCTGTCTCA AAAAAAAAAA AAAAGTGTTA TGATGCAGAC CTGTCAAAGA GGCAAAGGAG GGTGTTCCTA CACTCCAGGC ACTGTTCATA ACCTGGACTC TCATTCATTC TACAAATGGA GGGCTGCCCT

GGGCAGATCC CTGGAGCAGG CACTTTGCTG GTGTCTCGGT TAAAGAGAAA CTGATAACTC TTGGTATTAC CAAGAGATAG AGTCTCAGAT GGATATTCTT ACAGAAACAA TATTCCCACT TTTCAGAGTT CACCAAAAAA TCATTTTAGG CAGAGCTCAT CTGGCATTGA TCTGGTTCAT CCATGAGATT GGCTAGGGTA ACAGCACCTG GTCTTGCAGG GTTGTGTGAG CTTATCTCCA GGGTTGCCCC AACTCCGTCA GGAGCCTGAA CCCTGCATAC CGTATGTTCT CTGCCCCAGC CAAGAAAGGT CAATTTTCTC CTCAGAGGCT CCTGCAATTG ACAGAGAGCT CCCGAGGCAG AGAACAGCAC CCAAGGTAGA GACCCACACC CTCAATACAG ACAGGGAGGG CTATTGGCCC TTCATTGTAC CCATTTATCC ATCTGTAAGT GGGAAGATTC GTACAAAGAA GTGAATGAAG AAAAGTATGT GCATGTATAA ATCTGTGTGT CTTCCACTTT GTCCCACATA TACTAAATTT AAACATTCTT CTAACGTGGG AAAATCCAGT ATTTTAATGT GGACATCAAC TGCACAACGA TTGTCAGGAA AACAATGCAT ATTTGCATGG TGATACATTT GCAAAATGTG TCATAGTTTG CTACTCCTTG CCCTTCCATG AACCAGAGAA TTATCTCAGT TTATTAGTCC CCTCCCCTAA GAAGCTTCCA CCAATACTCT TTTCCCCTTT CCTTTAACTT GATTGTGAAA TCAGGTATTC AACAGAGAAA TTTCTCAGCC TCCTACTTCT GCTTTTGAAA GCTATAAAAA CAGCGAGGGA GAAACTGGCA GATACCAAAC CTCTTCGAGG CACAAGGCAC AACAGGCTGC TCTGGGATTC TCTTCAGCCA ATCTTCATTG CTCAAGTATG ACTTTAATCT TCCTTACAAC TAGGTGCTAA GGGAGTCTCT CTGTCTCTCT

GCCTCTTTGT GTGTATGCAT ATTCTCTCTC TCTCTCTCTT TCTTTCTCTG TCTCTCCTCT CCTTCCTCTC TGCCTCCTCT CTCAGCTTTT TGCAAAAATG CCAGGTGTAA TATAATGCTT ATGACTCGGG AAATATTCTG GGAATGGATA CTGCTTATCT AACAGCTGAC ACCCTAAAGG TTAGTGTCAA AGCCTCTGCT CCAGCTCTCC TAGCCAATAC ATTGCTAGTT GGGGTTTGGT TTAGCAAATG CTTTTCTCTA GACCCAAAGG ACTTCTCTTT CACACATTCA TTCATTTACT CAGAGATCAT TTCTTTGCAT GACTGCCATG CACTGGATGC TGAGAGAAAT CACACATGAA CGTAGCCGTC ATGGGGAAGT CACTCATTTT CTCCTTTTTA CACAGGTGTC TGAAGCAGCC ATGGCAGAAG TACCTGAGCT CGCCAGTGAA ATGATGGCTT ATTACAGGTC AGTGGAGACG CTGAGACCAG TAACATGAGC AGGTCTCCTC TTTCAAGAGT AGAGTGTTAT CTGTGCTTGG AGACCAGATT

TTTCCCCTAA ATTGCCTCTT TCAGTGGCAA ACAGGGTGCC AAGTAAATCT GATTTAAAGA CTACTTTCCC ATTACAAGTC CCTCCAGCCT TGGGACCTGG AGGCTATCCA GATGTGTTGT TGCAAGGGCT TCCTGCAGAG GCAAATGGGG AGAAAAGATT CCAAGCCCAC AATACAAGGA ATCCCTTTGC AAAGTGTGGC TTGGAGGGAG AGGGAGAGCT CAGATTTTAG CTGACTCTGC TGGGCTAGAG GTTAGGCCTC AAGATCCAAC AGGGAGCACC AGGGTGCCCA CCTGCCAGGC CTAGAATCTG CCTTCTGGAC TGTTCTGCGC ATATCACTGT GAAACTTGCC AGGTGTTTCA GGCAGCTTTG AGAGGCAGGG TGTTTGCAGT TTCTTATGAA CAGTCAAGTC TTGTACACAG GGAAGGAAAA ATAAACCTGT TTAGAAGACA TAATTGAGAC ATGTCCCTGT TTTTATTACA GTGGCAATGA GGATGACTTG TTCTTTGAAG CTGATGGCCC TAAACAGATG AAGGTAAGAC

TATGGGTTTA ACTCCCAACC CAAGGAAGGG CTCTAACACA GGGAAAGCTC AAAGAAGGGA GTTCTGGGCC ACTTTGATGC CATGGTATTT TGTTTTAGAA AGACTTTAAC CTCTTCCAGT GAGACACAGG CTGCACCACT TGCTGACCTG GCCACTTGGT CATCATATCA CCACAGTCAC TCACTAACGT TGGTGGTGGT GGCCACACTT GGTGGTGACA GGGGAGGAGT AGTGATAATG TTCCCATTTC ATAGTAGGAA GACAACCAAG TCTTCAACAT AAATTTGATT ATCCTTTTAA GAGATGGATT CAGCCTATGC CAATCACTTG AGTTAAACTC TGAAACCAAG AGATGATCTT GAGAACTAAC ATATGTCTAC CCCTTTTGAG TAGAATAGTT TTTTGCTACC TGGGGTGAAG CTTATAACAA CAAGACATAG ATGATATAAA CAAAAAGATG AATTGAGACT TGAAAGAAAA CCATTCACTT GCTGTTTGAC CTTGACAAGT CATTTTACCC GCTTTGGACC TCATCTGAAA AATAAAGGGC

TGAGCTGGAT GATCTCTGAG ATTCCAGCAT CCTGCAACCT CCAGTTCTGA AATATTTTCA GTTGTAGCTA AGGGCATTTG GGCAGCAAAT GGTCATTTTT CAGACTCATC CTTACAAAGA GCCATGTTAT ATTCCTGCTG TCCCTTCTGT TTTATATGAT GCTCAGTAGC CTTCCTAGGT GCCCAGCCAT CAGCCTAGCT AGGTCAGTTG TGCAGGTTGG AGGCAGCCAC TTTTCTCTGG CTTTATTTTA TTCCAGTTTG TGATAGCCTC CCCTAGCCTC ATAATCCAGT CCTCAATCTT GTTAAAAACA TATTTCTTTA GAAGTTTTAA GACTGGCATA ACTTCTTGGC TGCAGCTGTG GGAGGAGCCC ATTGGCTTGT CTGCCTGGCC TTTGCCCCCC ATTGCCTCTT CCAGCAGCTT GGCTCTGCTC CAGGCAGGAA ATTCTCTCCT GCTCAACTTT CTTTTGTGCA CTTACAGGTC TCTTTAACTG TCTTTCAAGC CTTTGAACCA TTATCAGCCT TAAGGCAACC TCAGTGAAGC CTTAATACGG

AGCTTCTCTG AATAAGAGGA AAGTGGTAAC ATTTCACAAA AAGTACTCTC ACAGGATTTG CAGAATGCCT ATGAGACAGT GTTATGAAAA AGGAAAAAAA AGAACAGTGT AGAAAAATTG AATACTTGCT GAGTGAGCAT AGGTGAATGG AAAATGTTAT GGTCATCTGC ATGAAAAAGC AAATCATAGT GTGACAGCAT TAGGGATACA AAAAGATATA GAGAAGGTAT ACATGTATGG TGTAGGTGGG GCATGTACAA AAAGATGACA AGTAGAATCG GGATTTATTC TAAAGAATAG CCTGTAAGGT GTCCAGAAGC CACATTCTAG TCTTGAGTCT GCCTCTACCT GCTGTGTGCC CTTGAGTACA CCCTTAACCT CCTTGAGCTT CAGAGAGGGA TAATCTTTTT ATTTTATTTT ATTTTATTTT GTTTTGTTTT GTTTTGTTTT GTTTTATGAG ACAGAGTCTC ACTCTGTTGC CCAGGCTGGA GTGCAGTGGT ACAATCTTGG CTTACTGCAT CCTCCACCTC CTGAGTTCAA GCGATTCTCC

TTCCTCAGTC TCCTGAATAG CTAGGATTAC AGGTGCACCC CACCACACCC AGCTAATTTT TGTATTTTTA GTAGAGAAGG GGTTTCGCCA TGTTGGCCAG GCTGGTTTTG AAGTCCTGAC CTAAATGATT CATCCACCTC GGCTTCCCAA AGTGCTGGGA TTACAGGCAT GAGCCACCAC GCCTGGCCCA GAGAGGGATG ATCTTTAGAA GCTCGGGATT CTTTCAAGCC CTTTCCTCCT CTCTGAGCTT TCTACTCTCT GATGTCAAAG CATGGTTCCT GGCAGGACCA CCTCACCAGG CTCCCTCCCT CGCTCTCTCC GCAGTGCTCC TTCCAGGACC TGGACCTCTG CCCTCTGGAT GGCGGCATCC AGCTACGAAT CTCCGACCAC CACTACAGCA AGGGCTTCAG GCAGGCCGCG TCAGTTGTTG TGGCCATGGA CAAGCTGAGG AAGATGCTGG TTCCCTGCCC ACAGACCTTC CAGGAGAATG ACCTGAGCAC CTTCTTTCCC TTCATCTTTG AAGAAGGTAG TTAGCCAAGA GCAGGCAGTA

GATCTCCACT TGTGTCCTCT TGGAAGTCAT CAAGCCCCAG CCAACTCAAT TCCCCCAGAG CCAAAGCCCT TTAAAGGTAG AAGGCCCAGC GGGGAGACAA AACAAAGAAG GCTGGAAACC AAAGCAATCA TCTCTTTAGT GGAAACTATT CTTAAAGAAG ATCTTGATGG CTACTGACAT TTGCAACTCC CTCACTCTTT CTCAGGGGCC TTTCACTTAC ATTGTCACCA GAGGTTCGTA ACCTCCCTGT GGGCTAGTGT TATGACCATC ACCATTTTAC CTAAGTAGCT CTGTTGCTCG GCCACAGTGA GCAGTAATAG ACCTGAAGCT GGAACCCATG TCTAATAGTG TCAGGTCCAG TGTTCTTAGC CACCCCACTC CCAGCTTCAT CCCTACTGGT GTTGTCATCA GACTTTGACC GTATATGCTC AGGTGTCCTC CAAGAAATCA AATTTTGCCA CCTCGCCTCA CGAGGCCTGC CCTTCTGATT TTATACCTAA ACAACATGTG CTCCACATTT CAGAACCTAT CTTCTTCGAC ACATGGGATA

ACGAGGCTTA TGTGCACGAT GCACCTGTAC GATCACTGAA CTGCACGCTC CGGGACTCAC AGCAAAAAAG CTTGGTGATG TCTGGTCCAT ATGAACTGAA AGCTCTCCAC CTCCAGGGAC AGGATATGGA GCAACAAGGT AAATGGAAAC ATCCTGGTTT CCCTGCCTGG CCTCCTGGCA GCTTGCTAAT TCTCCATGTT TTAAACAAAG TAGAAAGTTA ATTTAAGGCA AATGATCAAC ACAAGTGAAA AAAAATATTA AAAAGGAATA TACAAACTTT GGTCCTAGAA ATGGCACATT TGATTGCACT GGCCAGTGCA TTTGTTAACA GGAGTGTGAC CCTGAGAAAT TAGACGGCTC AAGCACTCCC AGGACCATGT CCACCCAAGT CTCTTGGGCA TAGTGCAGTG TCAATTCTTC CACAATATGG GGTCATTTGA TGGACATGGC CTAACTGCCT GTGGGTTCTC TCTTCCTGTT GTTGAGGCTG AAACAAGAGT OCTGGAGCGA TAATGTGTCC ATCCCCCTCC CCAGTCTTCC CCCCTTGCCC

CAACATCCGT CCCACCCAAT GCCAGGTGGT TCCTTGTAGG GAAATTTTAC CGCCCAGCAG GAACTTATAT CTCTCCGCTG TAACGGGCAA AAGTTTCAAG TGCGGTGAAC CCATCATTAG CTGTGGTGAT CTGCCTGGCA TCGTGCCACA GTAGCCAAAG CCTCTGCACA GGAGTGTGGG CAACTAAGGC TGCTGACTTT GAAGGACAGC CTCACTCAGG GGGAAGCTAT TTGCTCTCAG CCAGGCCAAG AAAATCCTGT TTCTTTGGAA TCGGGTAGTA AGAGTGATCC CAGGGCCTCC AATTGACACT GCTGTGACTG AGGAAGATCA AAATGAGTGT CTCTCTTTGG AGCCACTTTC CCAGCTCAGC CTCTCCTCTC CCAGTTTCTT CCCATGGGCT ACTCTCTGTT CCTGAAACAG TTCTGGTGCC TGATTTCTGG CAGAAGTACA GCTTCACCTC TTTCCTTTCC TTCCACATTG ATCAAGTTGT TCCGCTCCTG TGGATGGGCA CATTGCCAGC CAGTGACACA ATGGCTTCCT TCCTTCCTTC

CTTCAGCATT TAAAATGTAG ACCCTCTTTC ATTCTCCGTT CCTACTGCTA TGAGGCTCTG AGAAACCCTC AGGCCTTTGA GGGGAAACCC TAAATCAACA AAATGACCCT GCTATTGTCT GTGAGAAGTC AAGTTATCCT GTGTCTTAGG CCAAGGAACC TCACTGTGGG TTCCCACAGA GGCTACCAAT TACATGTATC CTACTCTCGG GGCTAGGGGT TGGGGTGACC CTGCATGCTG TGTCCCTAAC CACAAGACCC CCTTCTTTCT TCAGTGGTGT TCTCCATGTC CTTTGTACAA GGAGAAGAAA GTAATGACAA AATACCTGTG GCCTTGGGCC TCAAGGAAAA GAATCTGTAC CTGTCCTGCG TGTTGAAAGA TGATAAGCCC ACTCTACAGC TGGAGGTAAG TGAATGCTAT GGAATGAAGC CCTTCTCAGC CTCCTGCTAC CACTTATTCC CAGACAATTC ACCTTCTCCC CGCCCCCATC CCTAGGAAAA GCTGGGAACA GGTCTATTTG ACAAGTTTTG CATTAATGTA AATAAATTTA

ACATAATTTT TAACTGCGTG CAACCTTCAA TCCTGCTGCA GAAAATTAAA TCATTTTGCC GATGTTATTA TGTCCTACCA TAGTTACAAC CCCAACAGAT TATATATTGT TAGGGCTGCT CTCATTTGAT AGACACCTTG GGAAATAGAT GACTTAAAGG GTCCCATTAT CACGTCCACT CCACTCCCAA AATCACCACC ACTATCACCT CCAGCTTTCT CAGCAAAAGC TTCATTTCCA AGTTGATGTC ATTCTAGGAC CATAAGGAAA AATACAATAA AAAGCCCCTG GAAACTAGGT ACTTCAAGAA GCTCTAGCTT AATTTTCACC CCCCCAAAAA AAAAAAATTC TCACCTACAT TATGCTCCTC AGCATTTGGC ACTAAGTTTT AGAAAAGAAG AAGGGCTCTT TTAATAATCA CACAGAAAGT TGGGGGCCCA GTTACAACTC AGGAGTCTGG CTCCTGATCA TGTGACCTGC TCGTCAGTTT CCTTTCTGGC CAACCCAAAG AACATCTTTC CCATAGGCAT CTTTGTCCCT TGCCCCACAA

AAATTCTTCT TTCTCTTTCG CTGCAGAGTG TAGATCCCAA AAATTACCCA AAGAAGAAGA TGGAAAAGCG ATTTGTCTTC AACAAGATAG AAATCAATAA CAAGCTGGAA TTTGAGTCTG CCCAGTTCCC CAACTGGTAC ATCAGCACCT CTCAAGCAGA AAACATGCCC GTCTTCCTGG GAGGGACCAA AGGCGGCCAG GATATAACTG ACTTCACCAT GCAATTTGTG TCTTCCTAAA GAGAGCTGTA CCCAGAGAGT CCTGTGCTGA ATGTGGACTC AATCCCTAGG GCTGGCAGAA AGGGAACAGA AAGGTTTTTG AGTACGGCTA TAGCCTGGAC TTTCCTGTTG TCTACACCAA TGCCCAACTG CCTGCCTTAG GGTAGTGCTA AGAGGATCTC CTGTCCATCA GCCAGGACAG TCAGCTCTCT CCTTTCAGGG CCAATCCCCA GCCCTTTTGT TGAGCCAGGC CTCTCTCACC TCTCCTACTC ACTTAAAGCC CGCCTGACAG AAACCACGGC CACATTTGGT TCTAAGAAAC CCTCTGTCAT

TCGCTCCCAC ATTCTGATGA GCAACCGCTT CCCTATTTAT TTATTTATTT GTTTGTTTGT TTTGATTCAT TGGTCTAATT TATTCAAAGG GGGCAAGAAG TAGCAGTGTC TGTAAAAGAG CCTAGTTTTT AATAGCTATG GAATCAATTC AATTTGGACT GGTGTGCTCT CTTTAAATCA AGTCCTTTAA TTAAGACTGA AAATATATAA GCTCAGATTA TTTAAATGGG AATATTTATA AATGAGCAAA TATCATACTG TTCAATGGTT CTGAAATAAA CTTCACTGAA GAAAAAAAAA AAAGGGTCTC TCCTGATCAT TGACTGTCTG GATTGACACT GACAGTAAGC AAACAGGCTG TGAGAGTTCT TGGGACTAAG CCCACTCCTC ATTGCTGAGT GCTGCAAGTA CCTAGAAATA TCCTTGGCCA CCGAAGACTA TCCTCCTCAC CCATCCCCTT TATTTCGTTG TTCAACAGAA GGATATTCAG TGCACATCTG GAACAGGATC AGCTGAAGCA CTGCAGGGAG TCAGGACTGG TAGTAACAGC

TACCATGATT TATCTATCAA TGCACCAAAC ATCTGTTGAG CAAGCGCTAT GTACTAGGAG CTGGGAGTAC AGAGATGAGA ACAGTCACAA GTCCCTCCTC AGATAGGAGA GGCAOCTAGT TATAAGCAGA ACAAGGTAAC ATGACAAGTA GAGTAAGATA GAAGAACGAA GAGGAGTAGC CAGGAAGGAG GGAGGAGAAC GACATAAGAA TCAAGCCTAA AGGGATAAAC AGAAGATTTC CACACATGGG CTGGGCCAAT TGGGTGTCGG TTACGCCTGT AATCCCAGCA CTTTGGGTGG CAGGGGCAGA AAGATCGCTT GAGCCCAGGA GTTCAAGACC AGCCTGGGCA ACATAGTGAG ACTCCCATCT CTACAAAAAA TAAATAAATA AATAAAACAA TCAGCCAGGC ATGCTGGCAT GCACCTGTAG TCCTAGCTAC TTGGGAAGCT GACACTGGAG GATTGCTTGA GCCCAGAAGT TCAAGACTGC AGTGAGCTTA TCCGTTGACC TGCAGGTCGA C ACAAACCTTT

TCGAGGCAAA AGGCAAAAAA GGCTGCTCTG GGATTCTCTT CAGCCAATCT TCAATGCTCA AGTGTCTGAA GCAGCCATGG CAGAAGTACC TAAGCTCGCC AGTGAAATGA TGGCTTATTA CAGTGGCAAT GAGGATGACT TGTTCTTTGA AGCTGATGGC CCTAAACAGA TGAAGTGCTC CTTCCAGGAC CTGGACCTCT GCCCTCTGGA TGGCGGCATC CAGCTACGAA TCTCCGACCA CCACTACAGC AAGGGCTTCA GGCAGGCCGC GTCAGTTGTT GTGGCCATGG ACAAGCTGAG GAAGATGCTG GTTCCCTGCC CACAGACCTT CCAGGAGAAT GACCTGAGCA CCTTCTTTCC CTTCATCTTT GAAGAAGAAC CTATCTTCTT CGACACATGG GATAACGAGG CTTATGTGCA CGATGCACCT GTACGATCAC TGAACTGCAC GCTCCGGGAC TCACAGCAAA AAAGCTTGGT GATGTCTGGT CCATATGAAC TGAAAGCTCT CCACCTCCAG GGACAGGATA TGGAGCAACA AGTGGTGTTC

TCCATGTCCT TTGTACAAGG AGAAGAAAGT AATGACAAAA TACCTGTGGC CTTGGGCCTC AAGGAAAAGA ATCTGTACCT GTCCTGCGTG TTGAAAGATG ATAAGCCCAC TCTACAGCTG GAGAGTGTAG ATCCCAAAAA TTACCCAAAG AAGAAGATGG AAAAGCGATT TGTCTTCAAC AAGATAGAAA TCAATAACAA GCTGGAATTT GAGTCTGCCC AGTTCCCCAA CTGGTACATC AGCACCTCTC AAGCAGAAAA CATGCCCGTC TTCCTGGGAG GGACCAAAGG CGGCCAGGAT ATAACTGACT TCACCATGCA ATTTGTGTCT TCCTAAAGAG AGCTGTACCC AGAGAGTCCT GTGCTGAATG TGGACTCAAT CCCTAGGGCT GGCAGAAAGG GAACAGAAAG GTTTTTGAGT ACGGCTATAG CCTGGACTTT CCTGTTGTCT ACACCAATGC CCAACTGCCT GCCTTAGGGT AGTGCTAAGA GGATCTCCTG TCCATCAGCC AGGACAGTCA GCTCTCTCCT TTCAGGGCCA ATCCCAGCCC

TTTTGTTGAG CCAGGCCTCT CTCACCTCTC CTACTCACTT AAAGCCCGCC TGACAGAAAC CAGGCCACAT TTTGGTTCTA AGAAACCCTC CTCTGTCATT CGCTCCCACA TTCTGATGAG CAACCGCTTC CCTATTTATT TATTTATTTG TTTGTTTGTT TTGATTCATT GGTCTAATTT ATTCAAAGGG GGCAAGAAGT AGCAGTGTCT GTAAAAGAGC CTAGTTTTTA ATAGCTATGG AATCAATTCA ATTTGGACTG GTGTGCTCTC TTTAAATCAA GTCCTTTAAT TAAGACTGAA AATATATAAG CTCAGATTAT TTAAATGGGA ATATTTATAA ATGAGCAAAT ATCATACTGT TCAATGGTTC TCAAATAAAC TTCACT CTGGCAGGAG TAGCAGCTGC CCCTTGGCGC GACTGCTGGA GCCGCGAACT AGAGAAACAC AGACACGCCT CATAGAGCAA CGGCGTCTCT CGGAGCGTGG AGCCCGCCAA GCTCGAGCTG AGCTTTCGCT TGCCGTCCAC CACTGCCCAC ACTGTCGTTT

GCTGCCATCG CAGACCTGCT GCTGACTTCC ATCCCTCTGG ATCCGGCAAG GGCCTGCGAT TTTGACAATG TCAAGATTTA CCGTATATCC CTGTTTGTTT GGATACACCA GTGACGTCCA CTTCTAGAAG ACAAAGTTAT ATTACTTAAA CAACCAAAGA TATGAAACTA TCCATGAAGA ACAATATTAT CAATACACAG CAGTCTTTTG TAACCATGCC CAATGTGATT GTACCAGATA TTGAAAAGGA AATACGAAGG ATGGAAAATG GAGCATGCAG CTCCTTTTCT GAGGATGATG ACAGTGCCTC TACATCTGAA GAATCAGAGA ATGAAAACCC TCATGCAAGG GGTTCCTTTA GTTATAAGTC ACTCAGAAAG GGAGGACCAT CACAGAGGGA GCAGTACCTG CCTGGTGCCA TTGCCATTTT TAATGTGAAC AACAGCGACA ATAAGGACCA GGAACCAGAA GAAAAAAAGA AAAAGAAAAA AGAAAAGAAG AGCAAGTCAG ATGATAAAAA CGAAAATAAA AACGACCCAA

AGAAGAAGAT GGAAAAGCGA ATGGCCAAAG TTCCAGACAT GTTTGAAGAG CTGAAGAACT GTTACAGTGA AAATGAAGAA GACAGTTCCT CCATTGATCA

TCTGTCTCTG AATCAGAAAT CCTTCTATCA TGTAAGCTAT GGCCCACTCC ATGAAGGCTG CATGGATCAA TCTGTGTCTC TGAGTATCTC TGAAACCTCT AAAACATCCA AGCTTACCTT CAAGGAGAGC ATGGTGGTAG TAGCAACCAA CGGGAAGGTT CTGAAGAAGA GACGGTTGAG TTTAAGCCAA TCCATCACTG ATGATGACCT GGAGGCCATC GCCAATGACT CCTAGGTCAG CACCTTTTAG TGACGCCCTC AATCAAAGTA TAATTCGAGC CAATGATCAG TACCTCACGG CTGCTGCATT ACATAATCTG GATGAAGCAG TGAAATTTGA CATGGGTGCT TATAAGTCAT CAAAGGATGA TGCTAAAATT ACCGTGATTC TAAGAATCTC AAAAACTCAA TTGTATGTGA CTGCCCAAGA TGAAGACCAA CCAGTGCTGC TGAAGGAGAT GCCTGAGATA CCCAAAACCA TCACAGGTAG TGAGACCAAC CTCCTCTTCT TCTGGGAAAC TCACGGCACT AAGAACTATT TCACATCAGT TGCCCATCCA AACTTGTTTA TTGCCACAAA GCAAGACTAC TGGGTGTGCT TGGCAGGGGG GCCACCCTCT ATCACTGACT TTCAGATACT GGAAAACCAG GCGTAGGTCT GGAGTCTCAC TTGTCTCACT TGTGCAGTGT TGACAGTTCA TATGTACCAT GTACATGAAG AAGCTAAATC CTTTACTGTT AGTCATTTGC TGAGCATGTA CTGAGCCTTG TAATTCTAAA TGAATGTTTA CACTCTTTGT

AAGAGTGGAA CCAACACTAA CATATAATGT TGTTATTTAA AGAACACCCT ATATTTTGCA TAGTACCAAT CATTTTAATT ATTATTCTTC ATAACAATTT TAGGAGGACC AGAGCTACTG ACTATGGCTA CCAAAAAGAC TCTACCCATA TTACAGATGG GCAAATTAAG GCATAAGAAA ACTAAGAAAT ATGCACAATA GCAGTTGAAA CAAGAAGCCA CAGACCTAGG ATTTCATGAT TTCATTTCAA CTGTTTGCCT TCTGCTTTTA AGTTGCTGAT GAACTCTTAA TCAAATAGCA TAAGTTTCTG GGACCTCAGT TTTATCATTT TCAAAATGGA GGGAATAATA CCTAAGCCTT CCTGCCGCAA CAGTTTTTTA TGCTAATCAG GGAGGTCATT TTGGTAAAAT ACTTCTCGAA GCCGAGCCTC AAGATGAAGG CAAAGCACGA AATGTTATTT TTTAATTATT ATTTATATAT GTATTTATAA ATATATTTAA GATAATTATA ATATACTATA TTTATGGGAA CCCCTTCATC CTCTGAGTGT

GACCAGGCAT CCTCCACAAT AGCAGACAGT GTTTTCTGGG ATAAGTAAGT TTGATTTCAT TAATACAGGG CATTTTGGTC CAAGTTGTGC TTATCCCATA GCCAGGAAAC TCTGCATTCT AGTACTTGGG AGACCTGTAA TCATATAATA AATGTACATT AATTACCTTG AGCCAGTAAT TGGTCCGATC TTTGACTCTT TTGCCATTAA ACTTACCTGG GCATTCTTGT TTCATTCAAT TCCACCTGCA ATCAAGTCCT ACAAGCTAAA ATTAGATGAA CTCAACTTTG ACAACCATAG ACCACTGTTA TCAAAACTTT CTTTTCTGGA ATGTAATCAA TGTTTCTTCT AGGTTCTAAA AATTGTGATC AGACCATAAT GTTACATTAT TATCAACAAT AGTGATTGAT AGAGTGTTAT CAGTCATAAC TAAATAAAGC TTGCAAGTGA GGGAGTCATT TCATTGGCGT TTGAGTCAGC AAAGAAGTCA AG AGCTGCCAGC CAGAGAGGGA GTCATTTCAT TGGCGTTTGA GTCAGCAAAG

AAGTCAAGAT GGCCAAAGTT CCAGACATGT TTGAAGACCT GAAGAACTGT TACAGTGAAA ATGAAGAAGA CAGTTCCTCC ATTGATCATC TGTCTCTGAA TCAGAAATCC TTCTATCATG TAAGCTATGG CCCACTCCAT GAAGGCTGCA TGGATCAATC TGTGTCTCTG AGTATCTCTG AAACCTCTAA AACATCCAAG CTTACCTTCA AGGAGAGCAT GGTGGTAGTA GCAACCAACG GGAAGGTTCT GAAGAAGAGA CGGTTGAGTT TAAGCCAATC CATCACTGAT GATGACCTGG AGGCCATCGC CAATGACTCA GAGGAAGAAA TCATCAAGCC TAGGTCATCA CCTTTTAGCT TCCTGAGCAA TGTGAAATAC AACTTTATGA GGATCATCAA ATACGAATTC ATCCTGAATG ACGCCCTCAA TCAAAGTATA ATTCGAGCCA ATGATCAGTA CCTCACGGCT GCTGCATTAC ATAATCTGGA TGAAGCAGTG AAATTTGACA TGGGTGCTTA TAAGTCATCA AAGGATGATG

CTAAAATTAC CGTGATTCTA AGAATCTCAA AAACTCAATT GTATGTGACT GCCCAAGATG AAGACCAACC AGTGCTGCTG AAGGAGATGC CTGAGATACC CAAAACCATC ACAGGTAGTG AGACCAACCT CCTCTTCTTC TGGGAAACTC ACGGCACTAA GAACTATTTC ACATCAGTTG CCCATCCAAA CTTGTTTATT GCCACAAAGC AAGACTACTG GGTGTGCTTG GCAGGGGGGC CACCCTGTAT CACTGACTTT CAGATACTGG AAAACCAGGC GTAGGTCTGG AGTCTCACTT GTCTCACTTG TGCAGTGTTG ACAGTTCATA TGTACCATGT ACATGAAGAA GCTAAATCCT TTACTGTTAG TCATTTGCTG AGCATGTACT GAGCCTTGTA ATTCTAAATG AATGTTTACA CTCTTTGTAA GAGTGGAACC AACACTAACA TATAATGTTG TTATTTAAAG AACACCCTAT ATTTTGCATA GTACCAATCA TTTTAATTAT TATTCTTCAT AACAATTTTA GGAGGACCAG AGCTACTGAC

TATGGCTACC AAAAAGACTC TACCCATATT ACAGATGGGC AAATTAAGGC ATAAGAAAAC TAAGAAATAT GCACAATAGC AGTCGAAACA AGAAGCCACA GACCTAGGAT TTCATGATTT CATTTCAACT GTTTGCCTTC TGCTTTTAAG TTGCTGATGA ACTCTTAATC AAATAGCATA AGTTTCTGGG ACCTCAGTTT TATCATTTTC AAAATGGAGG GAATAATACC TAAGCCTTCC TGCCGCAACA GTTTTTTATG CTAATCAGGG AGGTCATTTT GGTAAAATAC TTCTCGAAGC CGAGCCTCAA GATGAAGGCA AAGCACGAAA TGTTATTTTT TAATTATTAT TTATATATGT ATTTATAAAT ATATTTAAGA TAATTATAAT ATACTATATT TATGGGAACC CCTTCATCCT CTGAGTGTGA CCAGGCATCC TCCACAATAG CAGACAGTGT TTTCTGGGAT AAGTAAGTTT GATTTCATTA ATACAGGGCA TTTTGGTCCA AGTTGTGCTT ATCCCATAGC CAGGAAACTC TGCATTCTAG

TACTTGGGAG ACCTGTAATC ATATAATAAA TGTACATTAA TTACCTTGAG CCAGTAATTG GTCCGATCTT TGACTCTTTT GCCATTAAAC TTAGCTGGGC ATTCTTGTTT CATTCAATTC CACCTGCAAT CAAGTCCTAC AAGCTAAAAT TAGATGAACT CAACTTTGAC AACCATGAGA CCACTGTTAT CAAAACTTTC TTTTCTGGAA TGTAATCAAT GTTTCTTCTA GGTTCTAAAA ATTGTGATCA GACCATAATG TTACATTATT ATCAACAATA GTGATTGATA GAGTGTTATC AGTCATAACT AAATAAAGCT TGCAACAAAA TTCTCTG-3' (FRAG. NO:_)(SEQ ID NO:11886) 5'-AAGCTTCTAC CCTAGTCTGG TGCTACACTT ACATTGCTTA CATCCAAGTG TGGTTATTTC TGTGGCTCCT GTTATAACTA TTATAGCACC AGGTCTATGA CCAGGAGAAT

TAGACTGGCA TTAAATCAGA ATAAGAGATT TTGCACCTGC AATAGACCTT ATGACACCTA ACCAACCCCA TTATTTACAA TTAAACAGGA ACAGAGGGAA TACTTTATCC AACTCACACA AGCTGTTTTC CTCCCAGATC CATGCTTTTT TGCGTTTATT ATTTTTTAGA GATGGGGGCT TCACTATGTT GCCCACACTG GACTAAAACT CTGGGCCTCA AGTGATTGTC CTGCCTCAGC CTCCTGAATA GCTGGGACTA CAGGGGCATG CCATCACACC TAGTTCATTT CCTCTATTTA AAATATACAT GGCTTAAACT CCAACTGGGA ACCCAAAACA TTCATTTGCT AAGAGTCTGG TGTTCTACCA CCTGAACTAG GCTGGCCACA GGAATTATAA AAGCTGAGAA ATTCTTTAAT AATAGTAACC AGGCAACATC ATTGAAGGCT CATATGTAAA AATCCATGCC TTCCTTTCTC CCAATCTCCA TTCCCAAACT TAGCCACTGG TTCTGGCTGA GGCCTTACGC ATACCTCCCG GGGCTTGCAC

ACACCTTCTT CTACAGAAGA CACACCTTGG GCATATCCTA CAGAAGACCA GGCTTCTCTC TGGTCCTTGG TAGAGGGCTA CTTTACTGTA ACAGGGCCAG GGTGGAGAGT TCTCTCCTGA AGCTCCATCC CCTCTATAGG AAATGTGTTG ACAATATTCA GAAGAGTAAG AGGATCAAGA CTTCTTTGTG CTCAAATACC ACTGTTCTCT TCTCTACCCT GCCCTAACCA GGAGCTTGTC ACCCCAAACT CTGAGGTGAT TTATGCCTTA ATCAAGCAAA CTTCCCTCTT CAGAAAAGAT GGCTCATTTT CCCTCAAAAG TTGCCAGGAG CTGCCAAGTA TTCTGCCAAT TCACCCTGGA GCACAATCAA CAAATTCAGC CAGAACACAA CTACAGCTAC TATTAGAACT ATTATTATTA ATAAATTCCT CTCCAAATCT AGCCCCTTGA CTTCGGATTT CACGATTTCT CCCTTCCTCC TAGAAACTTG ATAAGTTTCC CGCGCTTCCC TTTTTCTAAG ACTACATGTT TGTCATCTTA TAAAGCAAAG

GGGTGAATAA ATGAACCAAA TCAATAACTT CTGGAATATC TGCAAACAAC AATAATATCA GCTATGCCAT CTTTCACTAT TTTAGCCAGT ATCGAGTTGA ATGAACATAG AAAAATACAA AACTGAATTC TTCCCTGTAA ATTCCCCGTT TTGACGACGC ACTTGTAGCC ACGTAGCCAC GCCTACTTAA GACAATTACA AAAGGCGAAG AAGACTGACT CAGGCTTAAG CTGCCAGCCA GAGAGGGAGT CATTTCATTG GCGTTTGAGT CAGCAAAGGT ATTGTCCTCA CATCTCTGGC TATTAAAGTA TTTTCTGTTG TTGTTTTTCT CTTTGGCTGT TTTCTCTCAC ATTGCCTTCT CTAAAGCTAC AGTCTCTCCT TTCTTTTCTT GTCCCTCCCT GGTTTGGTAT GTGACCTAGA ATTACAGTCA GATTTCAGAA AATGATTCTC TCATTTTGCT GATAAGGACT GATTCGTTTT ACTGAGGGAC GGCAGAACTA GTTTCCTATG AGGGCATGGG TGAATACAAC TGAGGCTTCT CATGGGAGGG

AATCTCTACT ATCCAAAATT ATTAGGAGAA AATTGAAAAT TTCCAACTCT GTCTCTCTCT TACCTCTGTG TAAGGCAAAT ACCTTATTCT TGTGGTGTTT TTGTAACCTC TTCAAACTTT CATTGATTGA ATGCCTGTTC TGGCAATACA TTAGGTTGGG CACATAAGGA ATACCAACAT AAATAAAACA TTCTAAAAGA AGTTTACGAT CTAATAAAGG AGACAGGTAC ATAGCAAACT AATTCAAAGG AGCTAGAAGA TGGAGAAAAT GCTGAATGTG GACTAAGTCA TTCAACAAAG TTTTCAGGAA GCACAAAGAG GAGGGGCTCC CCTCACAGAT ATCTGGATTA GAGGCTGGCT GAGCTGATGG TGGCTGGTGT TCTCTGTTGC AGAAGTCAAG ATGGCCAAAG TTCCAGACAT GTTTGAAGAC CTGAAGAACT GTTACAGGTA AGGAATAAGA TTTATCTCTT GTGATTTAAT GAGGGTTTCA AGGCTCACCA GAATCCAGCT AGGCATAACA GTGGCCAGCA TGGGGGCAGG

CCGGCAGAGG TTGTAGAGAT GTGTACTAGT CCTGAAGTCA GAGCAGGTTC AGAGAAGACC CAGAAAAACT AAGCATTCAG CATGTTAAAC TGAGATTACA TTGGCAGGGA GACCGCCATT TTAGAAAAAT TATTTTTGAG GTCTGCTGAG CCCTACATGA ATATCAGCAT CAACTTAGAC ACAGCCTCTG TTGAGATCAC ATGCCCTGAT ATAAGAATGG GTTTTACTGG TCCATTCTCA GGAAAACTTG ATCTCATTCA GGAACAGGAA ATGGCTCCAC AGCAAGCTGG GCATGTGAAC TCACATATGC AGGCAAATCT CACTCAGATG TAGAAGAAAG GTAAATGAAC ACAAAGATAA AATTACGGAA CATATTAAAC TAACATGATG TTTCCATTAT CTGTAGTAAA TACTAACACA AACTAGGCTG TCAAAATTTT GCCTGGATAT TTTACTAAGT ATAAATTATG AAATCTGTTT TAGTGAATAC ATGAAAGTAA TGTGTAACAT ATAATCTATT TGGTTAAAAT AAAAAGGAAG TGCTTCAAAA

CCTTTCTTTT CTCTAAAGGA GCTTAACATT CTTCCCTGAA CTTCAATTAA AGCTCTTCAA TTTGTTAGCC AAGTCCAATT TTTACAGATA AAGCACAGGT AAAGCTCAAA GCCTGTCTTG ATGACTACTA ATTCCAGATT AGTAAGATAT GAATTACTCT ACCTATGTGT ATGTGTAGAA GTCCTTAAAT TTCAAAGATG ACAGTAATGG CCATGTGTAT GTGTGTGACC CACAACTATC ATGGTCATTA AAGTACATTG GCCAGAGACC ACATGAAATA ACAACAATTA CATTCTCATC ATCTTATTTT GACAGTGAAA ATGAAGAAGA CAGTTCCTCC ATTGATCATC TGTCTCTGAA TCAGGTAAGC AAATGACTGT AATTCTCATG GGACTGCTAT TCTTACACAG TGGTTTCTTC ATCCAAAGAG AACAGCAATG ACTTGAATCT TAAATACTTT TGTTTTACCC TCACTAGAGA TCCAGAGACC TGTCTTTCAT TATAAGTGAG ACCAGCTGCC TCTCTAAACT AATAGTTGAT GTGCATTGGC

TTCTCCCAGA ACAGAGCAGA ACTATCCCAA ATCCCTGAGA ACTGGAGTCT CCTGGGGCAG GCTTCATCAG GATGTTAGTT ATGCCATCCT GAGAAAGCCC CGCAGGCCGC TTCACCAGGT GTCTGTCTCC TAACGTGATG TGTTGTGGTT GTCTTCTCTG ACACCAGCAT CAGAGGTTAG AGAAAGTCTC CAAACATGAA GCTGAGAGAG AGGAAGCAAG CCAGCTGAAA GTGAGAAGTC TACAGCCACT CATCAATCTG TGTTATTGTG TTTGGAGACC ACAAATAGAC ACTATAAGTA CTGCCTAGTA TGTCTTCAGT ACTGGCTTTA AAAGCTGTCC CCAAAGGAGT ATTTCTAAAA TATTTTGAGC ATTGTTAAGC AGATTTTTAA CCTCCTGAGA GGGAACTAAT TGGAAAGCTA CCACTCACTA CAATCATTGT TAACCTATTT AGTTACAACA TCTCATTTTT GAGCATGCAA ATAAATGAAA AAGTCTTCCT AAAAAAATCA TCTTTTTATC CTGGAAGGAG GAAGGAAGGT GAGACAAAAG

GGAGAGAGGG AGGGAAGCCT AATGAAACAC CAGTTACCTA AGACCAGAAT GGAGATCCTC CTCACTACCT CTGTTGAATA CAGCACCTAC TGAAAGAACT TTCATTCCCT GACCATGAAC AGCCTCTCAG CTTCTGTTTT CCTTCCTCAC AGAAATGCTT CTATCATGTA AGCTATGGCC CACTCCATGA AGGCTGCATG GATCAATCTG TGTCTCTGAG TATCTCTGAA ACCTCTAAAA CATCCAAGCT TACCTTCAAG GAGAGCATGG TGGTAGTAGC AACCAACGGG AAGGTTCTGA AGAAGAGACG GTTGAGTTTA AGCCAATCCA TCACTGATGA TGACCTGGAG GCCATCGCCA ATGACTCAGA GGAAGGTAAG GGGTCAAGCA CAATAATATC TTTCTTTTAC AGTTTTAAGC AAGTAGGGAC AGTAGAATTT AGGGGAAAAT TAAACGTGGA GTCAGAATAA CAAGAAGACA ACCAAGCATT AGTCTGGTAA CTATACAGAG GAAAATTAAT TTTTATCCTT CTCCAGGAGG GAGAAATGAG

CAGTGGCCTG AATCGAGAAT ACTTGCTCAC AGCCATTATT TCTTAGCCAT ATTGTAAAGG TCGTGTGACT TTTAGCCTTT CAGGAGAAAG CAGTAATAAG ACCACTTACG AGCTATGTTC CTCTCATACT AACTATGCCT CCTTGGTCAT GTTACATAAT CTTTTCGTGA TTCAGTTTCC TCTACTGTAA AATGGAGATA ATCAGAATCC CCCACTCATT GGATTGTTGT AAAGATTAAG AGTCTCAGGC TTTACAGACT GAGCTAGCTG GGCCCTGCTG ACTGTTATAA AGATTAAATG AGTCAACATC CCCTAACTTC TGGACTAGAA TAATGTCTGG TACAAAGTAA GCACCCAATA AATGTTAGCT ATTACTATCA TTATTATTAT TATTTTATTT TTTTTTTTTG AGATGGAGTC TGGCTCTGTC ACCCAGGCTG GAGTGCAGTG GCACAATCTC GGCTCACTGC AAGCTCTGCC TCCTGGGTTC ATGCCATTCT CCTGCCTCAG CCTCCCGAGT AAGCTGGGAA TACAGGCACC CGCCACTGTT

CCCGGCTAAT TTTTTGTATT TTTAGTAGAG ACGGAGTTTC ACCGTGGTCT CCATCTCCTC GTGATCCACC CACCTTGGCC TCCCAAAGTG CCGGGATTAC AGGCGTGAGC CACCGCGCCC GGCCTATTAT TATTATTATT ACTACTACTA CTACCTATAT GAATACTACC AGCAATACTA ATTTATTAAT GACTGGATTA TGTCTAAACC TCACAAGAAT CCTACCTTCT CATTTTACAT AAAAGGAAAC TAAGCTCATT GAGATAGGTA AACTGCCCAA TGGCATACAT CTGTAAGTGG GAGAGCCTCA AATCTAATTC AGTTCTACCT GAGTAAAAAA ATCATGGTTT CTCCTCCATC CCTTTACTGT ACAAGCCTCC ACATGAACTA TAAACCCAAT ATTCCTGTTT TTAAGATAAT ACCTAAGCAA TAACGCATGT TCACCTAGAA GGTTTTAAAA TGTAACAAAA TATAAGAAAA TAAAAATCAC TCATATCGTC AGTGAGAGTT TACTACTGCC AGCACTATGG TATGTTTCCT TAAAATCTTT

GCTATACACA TACCTACATG TGAACAAATA TGTCTAACAT CAAGACCACA CTATTTACAA CTTTATATCC AGCTTTTCTT ACTTAGCAAT GTATTGAGGA CATTTTAGAG TGCCCGTTTT TCACCATTAT AAGCAATOCA ACAATGAACA TCTGTATAAA TAAATATTCA TTTCTCTCAC CCTTTATTTC CTTAGAATAT ATTCCTAGAA GTAGAATTTC CCAGAGCCAT GAGGATTTGT GACGCTATTG ATATGTGCCA CTTTGCACTC TCTGTGACAT ATATAATTAT TTTTAATGCA TTCATTTTTT TCTCAGAGTG CATTCGTTTG AAAACATAGA CGGGAAATAC TGGTAGTCTT CCTTGTCAGT TAGAAACACC CAAACAATGA AAAATGAAAA AGTTGCACAA ATAGTCTCTA AAAACAATGA AACTATTGCC TGAGGAATTG AAGTTTAAAA AGAAGCACAT AAGCAACAAC AAGGATAATC CTAGAAAACC AGTTCTGCTG ACTGGGTGAT TTCACTTCTC TTTGCTTCCT CATCTGGATT

GGAATATTCC TAATACCCCC TCCAGAACTA TTTTCCCTGT TTGTACTAGA CTGTGTATAT CATCTGTGTT TGTACATAGA CATTAATCTG CACTTGTGAT CATGGTTTTA GAAATCATCA AGCCTAGGTC ATCACCTTTT AGCTTCCTGA GCAATGTGAA ATACAACTTT ATGAGGATCA TCAAATACGA ATTCATCCTG AATGACGCCC TCAATCAAAG TATAATTCGA GCCAATGATC AGTACCTCAC GGCTGCTGCA TTACATAATC TGGATGAAGC AGGTACATTA AAATGGCACC AGACATTTCT GTCATCCTCC CCTCCTTTCA AATAGCTTGA AGCACAGCAC ATCCCAAGCC AGGGCAGAAG GTTCAACTAA ATCTGGAAGT TCCACAAGAG AGAAGTTTCC TATCTTTGAG AGTAAAGGGT TGTGCACAAA GCTAGCTGAT GTACTACCTC

TTTGGTTCTT TCAGACATTC TTACCCTCAA TTTTAAAACT GAGGAAACTG TCAGACATAT TAAATGATTT ACTCAGATTT ACCCAGAAGC CAATGAAGAA CAATCACTCT CCTTTAAAAA GTCTGTTGAT CAAACTCACA AGTAACACCA AACCAGGAAG ATCTTTATTA TCTCTGATAA CATATTTGTG AGGCAAAACC TCCAATAAGC TACAAATATG GCTTAAAGGA TGAAGTTTAG TGTCCAAAAA CTTTTATCAC ACACATCCAA TTTTCATGGC GGACATGTTT TAGTTTCAAC AGTATACATA TTTTCAAAGG TCCAGAGAGG CAATTTTGCA ATAAACAAGC AAGACTTTTT CTGATTGGAT GCACTTCAGC TAACATGCTT TCAACTCTAC ATTTACAAAT TATTTTGTGT TCTATTTTTC TACTTAATAT TATTTCTGCA ATTTTCCCAA TATTGACATC GTGTATGTAT TTGCCATTTT TAATATCACT AGACAATTCA ATCAGGTTGC TACGTTGGTC CCTTGGGTTT ACTCTAAATA GCTTGATTGC AAATATCTTT GTATATATTA TTGTTTTTTC TCCTATCTTG TAATTTCTTT GAGCACATCC CAAAGAGGAA TGCCTAGATC AATGGGCACA AATAATTTGA CAGCTCTTAT TAAACATTAT TCTGTAAGTA AAAACTGAAC TACTTTTCAG TATCACTAGC AACATATGAG TGTATCAGCT TCCTAAACCC CTCCATGTTA GGTCATTATG AACTTATGAT CTAACAAATT ACAGGGTCTT ATCCCACTAA TGAAATTATA AGAGATTCAA CACTTATTCA GCCCCGAAGG ATTCATTCAA CGTAGAAAAT TCTAAGAACA TTAACCAAGT ATTTACCTGC CTAGTGAGTG TGGAAGACAT TGTGAAGGAC ACAAAGATGT ATAGAATTCC ATTCCTGACT TCCAGGTATT TACACCATAG GTGGGGACCT

AACTACACAC ACACACACAC ACACACACAC ACACACACAC ACCATGCACA CACAATCTAC ATCAACACTT GATTTTATAC AAATACAATG AATTTACTTT CTTTTTGGTT CTTCTCTTCA CCAGTGAAAT TTGACATGGG TGCTTATAAG TCATCAAAGG ATGATGCTAA AATTACCGTG ATTCTAAGAA TCTCAAAAAC TCAATTGTAT GTGACTGCCC AAGATGAAGA CCAACCAGTG CTGCTGAAGG TCAGTTGTCC TTTGTCTCCA ACTTACCTTC ATTTACATCT CATATGTTTG TAAATAAGCC CAATAGGCAG ACACCTCTAA CAAGGTGACA CTGTCCTCTT TCCTTCCTAC CACAGCCCCC ACCTACCCAC CCCACTCCCA TTGATTCCAG AGGCGTGCCT AGGCAGGATC TATGAGAAAA TATAACAGAG AGTAAGAGGA AAATTACCTT CTTTCTTTTT CCTTTCCCTG CCTGACCTTA TTCACCTCCC ATCCCAGAGC ATCCATTTAT TCCATTGATC TTTACTGACA TCTATTATCT

GACCTACACA ATACTAGACA TTAGGACAAT GTGGCCTGCC TCCAAGAAAC TCAAATAAGC CAACTGAGAT CAGAGAGGAT TAATCACCTG CCAATGGGCA CAAAGCAACA AGCTGGGAGC CAAGTCCCAA AATGGGGCCT GCTGCTTCCA GTTCCCCTCT CTCTGCATTG ATGTCAGCAT TATCCTTCGT CCCAGTCCTG TCTCCACTAC CACTTTCCCC CTCAAACACA CACACACACA ACAGCCTTAG ATGTTTTCTC CACTGATAAG TAGGTGACTC AATTTGTAAG TATATAATCC AAGACCTTCT ATTCCCAAGT AGAATTTATG TGCCTGCCTG TGCTTTTCTA CCTGGATCAA GTGATGTCTA CAGAGTAGGG CAGTAGCTTC ATTCATGAAC TCATTCAACA AGCATTATTC ACTGAGAGCC TTGTATTTTT CAGGCATAGT GCCAACAGCA GTGTGGACAG TGGTGCATCA AAGCCTCTAG TCTCATAGAA CTTAGTCTTC TGGAGGATAT GGAAAACAGA CAACCCAAAC AACCAACAAA

AGAGCAAGAT GCTGCAAAAA AAAAAAAAAT GAATAGGGTG CTAAGATAGA GAAAAGTGGG AGAGTGCTAT TTAGACAAAG TGGTAAAAAC AAAGCCCCTT GTGAGATGAG AGCTGCCGAC AGAGGGGGCG GGTCATGGTT GTGGGTTTTT GGGTAGGACA TTCAGAGGAG GGGGCGGGTC GTGGTTGTGG GTTTTTGGGT AGGACATTCA GAGGAGGGGG CGGGTCGTGG TTGTGGGTTT TTGGGTAGGA CATTCAGAGG AGGGGGCGGG TCGTGGTTGT GGGTTTTTGG GTAGGACATT CAGAGGAGGG GGCGGGTCGT GGTTGTGGGT TTTTGGGACA TTCAGAGGAG TCTGAATGCA CCCAGGCCTA CAACTTCAAG ATGGTAAAGG ACAGCTCCAA GGATCAGAAG AAGCATTCTT GGAACTGGGG CATTTTGAGA AGGAGGAAAA ATATGCAGAG ACTAGTGCTT GCAGAGCTTG CATTTGGATT TCATTTGAGG TACAATGAAA

ACCCATTAAT GGGTTTCACA CAGTGCAATG GCCTGACCTC ACTTATATTT CCTAAAATAG AAAACAGATC AGAAGGAAGG CAATAGAGAA GCAGAAAGTC CAATGAGGAG GTTTCACAGC AGTCATGGGG GTGGGGTAAG GAAAAGAAGT GGAAAGAAAC AGACAGAATT GGGTTATATT TTGGAGATAG AACCAACAGA AGGAAGAGGA GAAACAACAT TTACTGAGAA GGGAAAAAGT AGGAGAGGAA TAGGTTTGGG AAATAAATCC TGCTGACATT GGAAACCCCA AGGAAGCCTC AAAAGTATAT TTACTTGCTT TAGATTTAAA AGAATAGGAA AGAAGCATCT CAACTTGGAA TTTGAAATCT ATTTTTCCAT AAAAGTATTG TTAAATTCTA CTCATACTCA CAAGAAAAGT ACATTCTAAA GAGTATATTG AAAGAGTTTA CTGATATACT TAGGAATTTT GTGTGTATGT GTGTGTGTGT ATGTGTGTGT GTGTGTTTAA CCTTCAATTG TTGACTTAAA TACTGAGATA

AATGTCATCT AAATGCTAAA TTGATTTCCC AAAGGTATGA TTTGTTCACT TGGAGATCAA AATGTTTAGG GGGCTTAGAA TCACTGTAGT GCTCAGATTT GATGCAAAAT GTCTTAGGCC TATGTTGAAG GCAGGACAGA AACAATGTTT CCCTCCTACC TGCCTGGATA CAGTAAGATA CTAGTGTCAC TGACAATCTT CATAACTAAT TTAGATCTCT CTCCAATCAA CTAAGGAAAT CAACTCTTAT TAATAGACTG GGCCACACAT CTACTAGGCA TGTAATAAAT GCTTGCTGAA TGAACAAATG AATGAAGAGC CTATAGCATC ATGTTACAGC CATAGTCCTA AAGTGGTGTT TCTCATGAAG GCCAAATGCT AAGGGATTGA GCTTCAGTCC TTTTTCTAAC ATCTTGTTCT CTAACAGAAT TCTCTTCTTT TCTTCATAGG AGATGCCTGA GATACCCAAA ACCATCACAG GTAGTGAGAC CAACCTCCTC TTCTTCTGGG AAACTCACGG CACTAAGAAC TATTTCACAT CAGTTGCCCA

TCCAAACTTG TTTATTGCCA CAAAGCAAGA CTACTGGGTG TGCTTGGCAG GGGGGCCACC CTCTATCACT GACTTTCAGA TACTGGAAAA CCAGGCGTAG GTCTGGAGTC TCACTTGTCT CACTTGTGCA GTGTTGACAG TTCATATGTA CCATGTACAT GAAGAAGCTA AATCCTTTAC TGTTAGTCAT TTGCTGAGCA TGTACTGAGC CTTGTAATTC TAAATGAATG TTTACACTCT TTGTAAGAGT GGAACCAACA CTAACATATA ATGTTGTTAT TTAAAGAACA CCCTATATTT TGCATAGTAC CAATCATTTT AATTATTATT CTTCATAACA ATTTTAGGAG GACCAGAGCT ACTGACTATG GCTACCAAAA AGACTCTACC CATATTACAG ATGGGCAAAT TAAGGCATAA GAAAACTAAG AAATATGCAC AATAGCAGTT GAAACAAGAA GCCACAGACC TAGGATTTCA TGATTTCATT TCAACTGTTT GCCTTCTGCT TTTAAGTTGC TGATGAACTC TTAATCAAAT AGCATAAGTT

TCTGGGACCT CAGTTTTATC ATTTTCAAAA TGGAGGGAAT AATACCTAAG CCTTCCTGCC GCAACAGTTT TTTATGCTAA TCAGGGAGGT CATTTTGGTA AAATACTTCT CGAAGCCGAG CCTCAAGATG AAGGCAAAGC ACGAAATGTT ATTTTTTAAT TATTATTTAT ATATGTATTT ATAAATATAT TTAAGATAAT TATAATATAC TATATTTATG GGAACCCCTT CATCCTCTGA GTGTGACCAG GCATCCTCCA CAATAGCAGA CAGTGTTTTC TGGGATAAGT AAGTTTGATT TCATTAATAC AGGGCATTTT GGTCCAAGTT GTGCTTATCC CATAGCCAGG AAACTCTGCA TTCTAGTACT TGGGAGACCT GTAATCATAT AATAAATGTA CATTAATTAC CTTGAGCCAG TAATTGGTCC GATCTTTGAC TCTTTTGCCA TTAAACTTAC CTGGGCATTC TTGTTTCATT CAATTCCACC TGCAATCAAG TCCTACAAGC TAAAATTAGA TGAACTCAAC TTTGACAACC ATGAGACCAC

TGTTATCAAA ACTTTCTTTT CTGGAATGTA ATCAATGTTT CTTCTAGGTT CTAAAAATTG TGATCAGACC ATAATGTTAC ATTATTATCA ACAATAGTGA TTGATAGAGT GTTATCAGTC ATAACTAAAT AAAGCTTGCA ACAAAATTCT CTGACACATA GTTATTCATT GCCTTAATCA TTATTTTACT GCATGGTAAT TAGGGACAAA TGGTAAATGT TTACATAAAT AATTGTATTT AGTGTTACTT TATAAAATCA AACCAAGATT TTATATTTTT TTCTCCTCTT TGTTAGCTGC CAGTATGCAT AAATGGCATT AAGAATGATA ATATTTCCGG GTTCACTTAA AGCTCATATT ACACATACAC AAAACATGTG TTCCCATCTT TATACAAACT CACACATACA GAGCTACATT AAAAACAACT AATAGGCCAG GCACGGTGGC TCAGACCTGT AATCCCAGCA CTTTGGGAGG-3' (FRAG NO _)(SEQ ID NO 11879)

5'-ACCAACCTCT TCGAGGCACA AGGCACAACA GGCTGCTCTG GGATTCTCTT CAGCCAATCT TCATTGCTCA AGTGTCTGAA GCAGCCATGG CAGAAGTACC TGAGCTCGCC AGTGAAATGA TGGCTTATTA CAGTGGCAAT GAGGATGACT TGTTCTTTGA AGCTGATGGC CCTAAACAGA TGAAGTGCTC CTTCCAGGAC CTGGACCTCT GCCCTCTGGA TGGCGGCATC CAGCTACGAA TCTCCGACCA CCAGTACAGC AAGGGCTTCA GGCAGGCCGC GTCAGTTGTT GTGGCCATGG ACAAGCTGAG GAAGATGCTG GTTCCCTGCC CACAGACCTT CCAGGAGAAT GACCTGAGCA CCTTCTTTCC CTTCATCTTT GAAGAAGAAC CTATCTTCTT CGACACATGG GATAACGAGG CTTATGTGCA CGATGCACCT GTACGATCAC TGAACTGCAC GCTCCGGGAC TCACAGCAAA AAAGCTTGGT GATGTCTGGT CCATATGAAC TGAAAGCTCT CCACCTCCAG GGACAGGATA

TGGAGCAACA AGTGGTGTTC TCCATGTCCT TTGTACAAGG AGAAGAAAGT AATGACAAAA TACCTGTGGC CTTGGGCCTC AAGGAAAAGA ATCTGTACCT GTCCTGCGTG TTGAAAGATG ATAAGCCCAC TCTACAGCTG GAGAGTGTAG ATCCCAAAAA TTACCCAAAG AAGAAGATGG AAAAGCGATT TGTCTTCAAC AAGATAGAAA TCAATAACAA GCTGGAATTT GAGTCTGCCC AGTTCCCCAA CTGGTACATC AGCACCTCTC AAGCAGAAAA CATGCCCGTC TTCCTGGGAG GGACCAAAGG CGGCCAGGAT ATAACTGACT TCACCATGCA ATTTGTGTCT TCCTAAAGAG AGCTGTACCC AGAGAGTCCT GTGCTGAATG TGGACTCAAT CCCTAGGGCT GGCAGAAAGG GAACAGAAAG GTTTTTGAGT ACGGCTATAG CCTGGACTTT CCTGTTGTCT ACACCAATGC CCAACTGCCT GCCTTAGGGT AGTGCTAAGA GGATCTCCTG TCCATCAGCC AGGACAGTCA GCTCTCTCCT

TTCAGGGCCA ATCCCCAGCC CTTTTGTTGA GCCAGGCCTC TCTCACCTCT CCTACTCACT TAAAGCCCGC CTGACAGAAA CCACGGCCAC ATTTGGTTCT AAGAAACCCT CTGTCATTCG CTCCCACATT CTGATGAGCA ACCGCTTCCC TATTTATTTA TTTATTTGTT TGTTTGTTTT ATTCATTGGT CTAATTTATT CAAAGGGGGC AAGAAGTAGC AGTGTCTGTA AAAGAGCCTA GTTTTTAATA GCTATGGAAT CAATTCAATT TGGACTGGTG TGCTCTCTTT AAATCAAGTC CTTTAATTAA GACTGAAAAT ATATAAGCTC AGATTATTTA AATGGGAATA TTTATAAATG AGCAAATATC ATACTGTTCA ATGGTTCTGA AATAAACTTC TCTGAAG-3' (FRAG NO J(SEQ ID NO 11880) 5'-AGAAAGAAAG AGAGAGAGAA AGAAAAGAAA GAGGAAGGAA GGAAGGAAGG AAGAAAGACA GGCTCTGAGG AAGGTGGCAG TTCCTACAAC GGGAGAACCA

GTGGTTAATT TGCAAAGTGG ATCCTGTGGA GGCANNCAGA GGAGTCCCCT AGGCCACCCA GACAGGGCTT TTAGCTATCT GCAGGCCAGA CACCAAATTT CAGGAGGGCT CAGTGTTAGG AATGGATTAT GGCTTATCAA ATTCACAGGA AACTAACATG TTGAACAGCT TTTAGATTTC CTGTGGAAAA TATAACTTAC TAAAGATGGA GTTCTTGTGA CTGACTCCTG ATATCAAGAT ACTGGGAGCC AAATTAAAAA TCAGAAGGCT GCTTGGAGAG CAAGTCCATG AAATGCTCTT TTTCCCACAG TAGAACCTAT TTCCCTCGTG TCTCAAATAC TTGCACAGAG GCTCACTCCC TTGGATAATG CAGAGCGAGC ACGATACCTG GCACATACTA ATTTGAATAA AATGCTGTCA AATTCCCATT CACCCATTCA AGCAGCAAAC TCTATCTCAC CTGAATGTAC ATGCCAGGCA CTGTGCTAGA CTTGGCTCAA AAAGATTTCA GTTTCCTGGA GGAACCAGGA GGGCAAGGTT TCAACTCAGT

GCTATAAGAA GTGTTACAGG CTGGACACGG TGGCTCACGC CTGTAATCCC AACATTTGGG AGGCCGAGGC GGGCAGATCA CAAGGTCAGG AGATCGAGAC CATCCTGGCT AACATGGTGA AACCCTGTCT CTACTAAAAA TACAAAAAAT TAGCCGGGCG TTGGCGGCAG GTGCCTGTAG TCCCAGCTGC TGGGGAGGCT GAGGCAGGAG AATGGTGTGA ACCCGGGAGG CGGAACTTGC AGGGGGCCGA GATCGTGCCA CTGCACTCCA GCCTGGGCGA CAGAGTGAGA CTCTGTCTCA AAAAAAAAAA AAAAGTGTTA TGATGCAGAC CTGTCAAAGA GGCAAAGGAG GGTGTTCCTA CACTCCAGGC ACTGTTCATA ACCTGGACTC TCATTCATTC TACAAATGGA GGGCTCCCCT GGGCAGATCC CTGGAGCAGG CACTTTGCTG GTGTCTCGGT TAAAGAGAAA CTGATAACTC TTGGTATTAC CAAGAGATAG AGTCTCAGAT GGATATTCTT ACAGAAACAA

TATTCCCACT TTTCAGAGTT CACCAAAAAA TCATTTTAGG CAGAGCTCAT CTGGCATTGA TCTGGTTCAT CCATGAGATT GGCTAGGGTA ACAGCACCTG GTCTTGCAGG GTTGTGTGAG CTTATCTCCA GGGTTGCCCC AACTCCGTCA GGAGCCTGAA CCCTGCATAC CGTATGTTCT CTGCCCCAGC CAAGAAAGGT CAATTTTCTC CTCAGAGGCT CCTGCAATTG ACAGAGAGCT CCCGAGGCAG AGAACAGCAC CCAAGGTAGA GACCCACACC CTCAATACAG ACAGGGAGGG CTATTGGCCC TTCATTGTAC CCATTTATCC ATCTGTAAGT GGGAAGATTC CTAAACTTAA GTACAAAGAA GTGAATGAAG AAAAGTATGT GCATGTATAA ATCTGTGTGT CTTCCACTTT GTCCCACATA TACTAAATTT AAACATTCTT CTAACGTGGG AAAATCCAGT ATTTTAATGT GGACATCAAC TGCACAACGA TTGTCAGGAA AACAATGCAT ATTTGCATGG TGATACATTT GCAAAATGTG

TCATAGTTTG CTACTCCTTG CCCTTCCATG AACCAGAGAA TTATCTCAGT TTATTAGTCC CCTCCCCTAA GAAGCTTCCA CCAATACTCT TTTCCCCTTT CCTTTAACTT GATTGTGAAA TCAGGTATTC AACAGAGAAA TTTCTCAGCC TCCTACTTCT GCTTTTGAAA GCTATAAAAA CAGCGAGGGA GAAACTGGCA GATACCAAAC CTCTTCGAGG CACAAGGCAC AACAGGCTGC TCTGGGATTC TCTTCAGCCA ATCTTCATTG CTCAAGTATG ACTTTAATCT TCCTTACAAC TAGGTGCTAA GGGAGTCTCT CTGTCTCTCT GCCTCTTTGT GTGTATGCAT ATTCTCTCTC TCTCTCTCTT TCTTTCTCTG TCTCTCCTCT CCTTCCTCTC TGCCTCCTCT CTCAGCTTTT TGCAAAAATG CCAGGTGTAA TATAATGCTT ATGACTCGGG AAATATTCTG GGAATGGATA CTGCTTATCT AACAGCTGAC ACCCTAAAGG TTAGTGTCAA AGCCTCTGCT CCAGCTCTCC TAGCCAATAC

ATTGCTAGTT GGGGTTTGGT TTAGGAAATG CTTTTCTCTA GACCCAAAGG ACTTCTCTTT CACACATTCA TTCATTTACT CAGAGATCAT TTCTTTGCAT GACTGCCATG CACTGGATGC TGAGAGAAAT CACACATGAA CGTAGCCGTC ATGGGGAAGT CACTCATTTT CTCCTTTTTA CACAGGTGTC TGAAGCAGCC ATGGCAGAAG TACCTGAGCT CGCCAGTGAA ATGATGGCTT ATTACAGGTC AGTGGAGACG CTGAGACCAG TAACATGAGC AGGTCTCCTC TTTCAAGAGT AGAGTGTTAT CTGTGCTTGG AGACCAGATT TTTCCCCTAA ATTGCCTCTT TCAGTGGCAA ACAGGGTGCC AAGTAAATCT GATTTAAAGA CTACTTTCCC ATTACAAGTC CCTCCAGCCT TGGGACCTGG AGGCTATCCA GATGTGTTGT TGCAAGGGCT TCCTGCAGAG GCAAATGGGG AGAAAAGATT CCAAGCCCAC AATACAAGGA ATCCCTTTGC AAAGTGTGGC TTGGAGGGAG

AGGGAGAGCT CAGATTTTAG CTGACTCTGC TGGGCTAGAG GTTAGGCCTC AAGATCCAAC AGGGAGCACC AGGGTGCCCA CCTGCCAGGC CTAGAATCTG CCTTCTGGAC TGTTCTGCGC ATATCACTGT GAAACTTGCC AGGTGTTTCA GGCAGCTTTG AGAGGCAGGC TGTTTGCAGT TTCTTATGAA CAGTCAAGTC TTGTACACAG GGAAGGAAAA ATAAACCTGT TTAGAAGACA TAATTGAGAC ATGTCCCTGT TTTTATTACA GTGGCAATGA GGATGACTTG TTCTTTGAAG CTGATGGCCC TAAACAGATG AAGGTAAGAC TATGGGTTTA ACTCCCAACC CAAGGAAGGG CTCTAACACA GGGAAAGCTC AAAGAAGGGA GTTCTGGGCC ACTTTGATGC CATGGTATTT TGTTTTAGAA AGACTTTAAC CTCTTCCAGT GAGACACAGG CTGCACCACT TGCTGACCTG GCCACTTGGT CATCATATCA CCACAGTCAC TCACTAACGT TGGTGGTGGT GGCCACACTT GGTGGTGACA

GGGGAGGAGT AGTGATAATG TTCCCATTTC ATAGTAGGAA GACAACCAAG TCTTCAACAT AAATTTGATT ATCCTTTTAA GAGATGGATT CAGCCTATGC CAATCACTTG AGTTAAACTC TGAAACCAAG AGATGATCTT GAGAACTAAC ATATGTCTAC CCCTTTTGAG TAGAATAGTT TTTTGCTACC TGGGGTGAAG CTTATAACAA CAAGAGATAG ATGATATAAA CAAAAAGATG AATTGAGACT TGAAAGAAAA CCATTCACTT GCTGTTTGAC CTTGACAAGT CATTTTACCC GCTTTGGACC TCATCTGAAA AATAAAGGGC TGAGCTGGAT GATCTCTGAG ATTCCAGCAT CCTGCAACCT CCAGTTCTGA AATATTTTCA GTTGTAGCTA AGGGCATTTG GGCAGCAAAT GGTCATTTTT CAGACTCATC CTTACAAAGA GCCATGTTAT ATTCCTGCTG TCCCTTCTGT TTTATATGAT GCTCAGTAGC CTTCCTAGGT GCCCAGCCAT CAGCCTAGCT AGGTCAGTTG TGCAGGTTGG

AGGCAGCCAC TTTTCTCTGG CTTTATTTTA TTCCAGTTTG TGATAGCCTC CCCTAGCCTC ATAATCCAGT CCTCAATCTT GTTAAAAACA TATTTCTTTA GAAGTTTTAA GACTGGCATA ACTTCTTGGC TGCAGCTGTG GGAGGAGCCC ATTGGCTTGT CTGCCTGGCC TTTGCCCCCC ATTGCCTCTT CCAGCAGCTT GGCTCTGCTC CAGGCAGGAA ATTCTCTCCT GCTCAACTTT CTTTTGTGCA CTTACAGGTC TCTTTAACTG TCTTTCAAGC CTTTGAACCA TTATCAGCCT TAAGGCAACC TCAGTGAAGC CTTAATACGG AGCTTCTCTG AATAAGAGGA AAGTGGTAAC ATTTCACAAA AAGTACTCTC ACAGGATTTG CAGAATGCCT ATGAGACAGT GTTATGAAAA AGGAAAAAAA AGAACAGTGT AGAAAAATTG AATACTTGCT GAGTGAGCAT AGGTGAATGG AAAATGTTAT GGTCATCTGC ATGAAAAAGC AAATCATAGT GTGACAGCAT TAGGGATACA AAAAGATATA GAGAAGGTAT ACATGTATGG TGTAGGTGGG GCATGTACAA AAAGATGACA AGTAGAATCG GGATTTATTC TAAAGAATAG CGTGTAAGGT GTCCAGAAGC CACATTCTAG TCTTGAGTCT GCCTCTACCT GCTGTGTGCC CTTGAGTACA CCCTTAACCT CCTTGAGCTT CAGAGAGGGA TAATCTTTTT ATTTTATTTT ATTTTATTTT GTTTTGTTTT GTTTTGTTTT GTTTTATGAG ACAGAGTCTC ACTCTGTTGC CCAGGCTGGA GTGCAGTGGT ACAATCTTGG CTTACTGCAT CCTGCACCTC CTGAGTTCAA GCGATTCTCC TTCCTCAGTC TCCTGAATAG CTAGGATTAC AGGTGCACCC CACCACACCC AGCTAATTTT TGTATTTTTA GTAGAGAAGG GGTTTCGCCA TGTTGGCCAG GCTGGTTTTG

AAGTCCTGAC CTAAATGATT CATCCACCTC GGCTTCCCAA AGTGCTGGGA TTACAGGCAT GAGCCACCAC GCCTGGCCCA GAGAGGGATG ATCTTTAGAA GCTCGGGATT CTTTCAAGCC CTTTCCTCCT CTCTGAGCTT TCTACTCTCT GATGTCAAAG CATGGTTCCT GGCAGGACCA CCTCACCAGG CTCCCTCCCT CGCTCTCTCC GCAGTGCTCC TTCCAGGACC TGGACCTCTG CCCTCTGGAT GGCGGCATCC AGCTACGAAT CTCCGACCAC CACTACAGCA AGGGCTTCAG GCAGGCCGCG TCAGTTGTTG TGGCCATGGA CAAGCTGAGG AAGATGCTGG TTCCCTGCCC ACAGACCTTC CAGGAGAATG ACCTGAGCAC CTTCTTTCCC TTCATCTTTG AAGAAGGTAG TTAGCCAAGA GCAGGCAGTA GATCTCCACT TGTGTCCTCT TGGAAGTCAT CAAGCCCCAG CCAACTCAAT TCCCCCAGAG CCAAAGCCCT TTAAAGGTAG AAGGCCCAGC GGGGAGACAA AACAAAGAAG

GCTGGAAACC AAAGCAATCA TCTCTTTAGT GGAAACTATT CTTAAAGAAG ATCTTGATGG CTACTGACAT TTGCAACTCC CTCACTCTTT CTCAGGGGCC TTTCACTTAC ATTGTCACCA GAGGTTCGTA ACCTCCCTGT GGGCTAGTGT TATGACCATC ACCATTTTAC CTAAGTAGCT CTGTTGCTCG GCCACAGTGA GCAGTAATAG ACCTGAAGCT GGAACCCATG TCTAATAGTG TCAGGTCCAG TGTTCTTAGC CACCCCACTC CCAGCTTCAT CCCTACTGGT GTTGTCATCA GACTTTGACC GTATATGCTC AGGTGTCCTC CAAGAAATCA AATTTTGCCA CCTCGCCTCA CGAGGCCTGC CCTTCTGATT TTATACCTAA ACAACATGTG CTCCACATTT CAGAACCTAT CTTCTTCGAC ACATGGGATA ACGAGGCTTA TGTGCACGAT GCACCTGTAC GATCACTGAA CTGCACGCTC CGGGACTCAC AGCAAAAAAG CTTGGTGATG TCTGGTCCAT ATGAACTGAA AGCTCTCCAC

CTCCAGGGAC AGGATATGGA GCAACAAGGT AAATGGAAAC ATCCTGGTTT CCCTGCCTGG CCTCCTGGCA GCTTGCTAAT TCTCCATGTT TTAAACAAAG TAGAAAGTTA ATTTAAGGCA AATGATCAAC ACAAGTGAAA AAAAATATTA AAAAGGAATA TACAAACTTT GGTCCTAGAA ATGGCACATT TGATTGCACT GGCCAGTGCA TTTGTTAACA GGAGTGTGAC CCTGAGAAAT TAGACGGCTC AAGCACTCCC AGGACCATGT CCACCCAAGT CTCTTGGGCA TAGTGCAGTG TCAATTCTTC CACAATATGG GGTCATTTGA TGGACATGGC CTAACTGCCT GTGGGTTCTC TCTTCCTGTT GTTGAGGCTG AAACAAGAGT GCTGGAGCGA TAATGTGTCC ATCCCCCTCC CCAGTCTTCC CCCCTTGCCC CAACATCCGT CCCACCCAAT GCCAGGTGGT TCCTTGTAGG GAAATTTTAC CGCCCAGCAG GAACTTATAT CTCTCCGCTG TAACGGGCAA AAGTTTCAAG TGCGGTGAAC

CCATCATTAG CTGTGGTGAT CTGCCTGGCA TCGTGCCACA GTAGCCAAAG CCTCTGCACA GGAGTGTGGG CAACTAAGGC TGCTGACTTT GAAGGACAGC CTCACTCAGG GGGAAGCTAT TTGCTCTCAG CCAGGCCAAG AAAATCCTGT TTCTTTGGAA TCGGGTAGTA AGAGTGATCC CAGGGCCTCC AATTGACACT GCTGTGACTG AGGAAGATCA AAATGAGTGT CTCTCTTTGG AGCCACTTTC CCAGCTCAGC GTCTCCTCTC CCAGTTTCTT CGCATGGGCT ACTGTCTGTT CCTGAAACAG TTCTGGTGCC TGATTTCTGG CAGAAGTACA GCTTCACCTC TTTCCTTTCC TTCCACATTG ATCAAGTTGT TCCGCTCCTG TGGATGGGCA CATTGCCAGC CAGTGACACA ATGGCTTCCT TCCTTCCTTC CTTCAGCATT TAAAATGTAG ACCCTCTTTC ATTCTCCGTT CCTACTGCTA TGAGGCTCTG AGAAACCCTC AGGCCTTTGA GGGGAAACCC TAAATCAACA AAATGACCCT

GCTATTGTCT GTGAGAAGTC AAGTTATCCT GTGTCTTAGG CCAAGGAACC TCACTGTGGG TTCCCACAGA GGCTACCAAT TACATGTATC CTACTCTCGG GGCTAGGGGT TGGGGTGACC CTGCATGCTG TGTCCCTAAC CACAAGACCC CCTTCTTTCT TCAGTGGTGT TCTCCATGTC CTTTGTACAA GGAGAAGAAA GTAATGACAA AATACCTGTG GCCTTGGGCC TCAAGGAAAA GAATCTGTAC CTGTCCTGCG TGTTGAAAGA TGATAAGCCC ACTCTACAGC TGGAGGTAAG TGAATGCTAT GGAATGAAGC CCTTCTCAGC CTCCTGCTAC CACTTATTCC CAGACAATTC ACCTTCTCCC CGCCCCCATC CCTAGGAAAA GCTGGGAACA GGTCTATTTG ACAAGTTTTG CATTAATGTA AATAAATTTA ACATAATTTT TAACTGCGTG CAACCTTCAA TCCTGCTGCA GAAAATTAAA TCATTTTGCC GATGTTATTA TGTCCTACCA TAGTTACAAC CCCAACAGAT TATATATTGT

TAGGGCTGCT CTCATTTGAT AGACACCTTG GGAAATAGAT GACTTAAAGG GTCCCATTAT CACGTCCACT CCACTCCCAA AATCACCACC ACTATCACCT CCAGCTTTCT CAGCAAAAGC TTCATTTCCA AGTTGATGTC ATTCTAGGAC CATAAGGAAA AATACAATAA AAAGCCCCTG GAAACTAGGT ACTTCAAGAA GCTCTAGCTT AATTTTCACC CCCCCAAAAA AAAAAAATTC TCACCTACAT TATGCTCCTC AGCATTTGGC ACTAAGTTTT AGAAAAGAAG AAGGGCTCTT TTAATAATCA CACAGAAAGT TGGGGGCCCA GTTACAACTC AGGAGTCTGG CTCCTGATCA TGTGACCTGC TCGTCAGTTT CCTTTCTGGC CAACCCAAAG AACATCTTTC CCATAGGCAT CTTTGTCCCT TGCCCCACAA AAATTCTTCT TTCTCTTTCG CTGCAGAGTG TAGATCCCAA AAATTACCCA AAGAAGAAGA TGGAAAAGCG ATTTGTCTTC AACAAGATAG AAATCAATAA CAAGCTGGAA

TTTGAGTCTG CCCAGTTCCC CAACTGGTAC ATCAGCACCT CTCAAGCAGA AAACATGCCC GTCTTCCTGG GAGGGACCAA AGGCGGCCAG GATATAACTG ACTTCACCAT GCAATTTGTG TCTTCCTAAA GAGAGCTGTA CCCAGAGAGT CCTGTGCTGA ATGTGGACTC AATCCCTAGG GCTGGCAGAA AGGGAACAGA AAGGTTTTTG AGTACGGCTA TAGCCTGGAC TTTCCTGTTG TCTACACCAA TGCCCAACTG CCTGCCTTAG GGTAGTGCTA AGAGGATCTC CTGTCCATCA GCCAGGACAG TCAGCTCTCT CCTTTCAGGG CCAATCCCCA GCCCTTTTGT TGAGCCAGGC CTCTCTCACC TCTCCTACTC ACTTAAAGCC CGCCTGACAG AAACCACGGC CACATTTGGT TCTAAGAAAC CCTCTGTCAT TCGCTCCCAC CCCTATTTAT TTATTTATTT GTTTGTTTGT TTTGATTCAT TGGTCTAATT TATTCAAAGG GGGCAAGAAG TAGCAGTGTC

TGTAAAAGAG CCTAGTTTTT AATAGCTATG GAATCAATTC AATTTGGACT GGTGTGCTCT CTTTAAATCA AGTCCTTTAA TTAAGACTGA AAATATATAA GCTCAGATTA TTTAAATGGG AATATTTATA AATGAGCAAA TATCATACTG TTCAATGGTT CTGAAATAAA CTTCACTGAA GAAAAAAAAA AAAGGGTCTC TCCTGATCAT TGACTGTCTG GATTGACACT GACAGTAAGC AAACAGGCTG TGAGAGTTCT TGGGACTAAG CCCACTCCTC ATTGCTGAGT GCTGCAAGTA CCTAGAAATA TCCTTGGCCA CCGAAGACTA TCCTCCTCAC CCATCCCCTT TATTTCGTTG TTCAACAGAA GGATATTCAG TGCACATCTG GAACAGGATC AGCTGAAGCA CTGCAGGGAG TCAGGACTGG TAGTAACAGC TACCATGATT TATCTATCAA TGCACCAAAC ATCTGTTGAG CAAGCGCTAT GTACTAGGAG CTGGGAGTAC AGAGATGAGA ACAGTCACAA GTCCCTCCTC AGATAGGAGA

GGCAGCTAGT TATAAGCAGA ACAAGGTAAC ATGACAAGTA GAGTAAGATA GAAGAACGAA GAGGAGTAGC CAGGAAGGAG GGAGGAGAAC GACATAAGAA TCAAGCCTAA AGGGATAAAC AGAAGATTTC CACACATGGG CTGGGCCAAT TGGGTGTCGG TTACGCCTGT AATCCCAGCA CTTTGGGTGG CAGGGGCAGA AAGATCGCTT GAGCCCAGGA GTTCAAGACC AGCCTGGGCA ACATAGTGAG ACTCCCATCT CTACAAAAAA TAAATAAATA AATAAAACAA TCAGCCAGGC ATGCTGGCAT GCACCTGTAG TCCTAGCTAC TTGGGAAGCT GACACTGGAG GATTGCTTGA GCCCAGAAGT TCAAGACTGC AGTGAGCTTA TCCGTTGACC TGCAGGTCGA C-3' (FRAG NO J(SEQ ID NO 11881)

5'-ACAAACCTTT TCGAGGCAAA AGGCAAAAAA GGCTGCTCTG GGATTCTCTT CAGCCAATCT TCAATGCTCA AGTGTCTGAA GCAGCCATGG CAGAAGTACC TAAGCTCGCC AGTGAAATGA TGGCTTATTA CAGTGGCAAT GAGGATGACT TGTTCTTTGA AGCTGATGGC CCTAAACAGA TGAAGTGCTC CTTCCAGGAC CTGGACCTCT GCCCTCTGGA TGGCGGCATC CAGCTACGAA TCTCCGACCA CCACTACAGC AAGGGCTTCA GGCAGGCCGC GTCAGTTGTT GTGGCCATGG ACAAGCTGAG GAAGATGCTG GTTCCCTGCC CACAGACCTT CCAGGAGAAT GACCTGAGCA CCTTCTTTCC CTTCATCTTT GAAGAAGAAC CTATCTTCTT CGACACATGG GATAACGAGG CTTATGTGCA CGATGCACCT GTACGATCAC TGAACTGCAC GCTCCGGGAC TCACAGCAAA AAAGCTTGGT GATGTCTGGT CCATATGAAC TGAAAGCTCT CCACCTCCAG GGACAGGATA

TGGAGCAACA AGTGGTGTTC TCCATGTCCT TTGTACAAGG AGAAGAAAGT AATGACAAAA TACCTGTGGC CTTGGGCCTC AAGGAAAAGA ATCTGTACCT GTCCTGCGTG TTGAAAGATG ATAAGCCCAC TCTACAGCTG GAGAGTGTAG ATCCCAAAAA TTACCCAAAG AAGAAGATGG AAAAGCGATT TGTCTTCAAC AAGATAGAAA TCAATAACAA GCTGGAATTT GAGTCTGCCC AGTTCCCCAA CTGGTACATC AGCACCTCTC AAGCAGAAAA CATGCCCGTC TTCCTGGGAG GGACCAAAGG CGGCCAGGAT ATAACTGACT TCACCATGCA ATTTGTGTCT TCCTAAAGAG AGCTGTACCC AGAGAGTCCT GTGCTGAATG TGGACTCAAT CCCTAGGGCT GGCAGAAAGG GAACAGAAAG GTTTTTGAGT ACGGCTATAG CCTGGACTTT CCTGTTGTCT ACACCAATGC CCAACTGCCT GCCTTAGGGT AGTGCTAAGA GGATCTCCTG TCCATCAGCC AGGACAGTCA GCTCTCTCCT

TTCAGGGCCA ATCCCAGCCC TTTTGTTGAG CCAGGCCTCT CTCACCTCTC CTACTCACTT AAAGCCCGCC TGACAGAAAC CAGGCCACAT TTTGGTTCTA AGAAACCCTC CTCTGTCATT CGCTCCCACA TTCTGATGAG CAACCGCTTC CCTATTTATT TATTTATTTG TTTGTTTGTT TTGATTCATT GGTCTAATTT ATTCAAAGGG GGCAAGAAGT AGCAGTGTCT GTAAAAGAGC CTAGTTTTTA ATAGCTATGG AATCAATTCA ATTTGGACTG GTGTGCTCTC TTTAAATCAA GTCCTTTAAT TAAGACTGAA AATATATAAG CTCAGATTAT TTAAATGGGA ATATTTATAA ATGAGCAAAT ATCATACTGT TCAATGGTTC TCAAATAAAC TTCACT-3' (FRAG NO J(SEQ DD NO 11882) S'-CTGGCAGGAG TAGCAGCTGC CCCTTGGCGC GACTGCTGGA GCCGCGAACT AGAGAAACAC AGACACGCCT CATAGAGCAA CGGCGTCTCT CGGAGCGTGG

AGCCCGCCAA GCTCGAGCTG AGCTTTCGCT TGCCGTCCAC CACTGCCCAC ACTGTCGTTT GCTGCCATCG CAGACCTGCT GCTGACTTCC ATCCCTCTGG ATCCGGCAAG GGCCTGCGAT TTTGACAATG TCAAGATTTA CCGTATATCC CTGTTTGTTT GGATACACCA GTGACGTCCA CTTCTAGAAG ACAAAGTTAT ATTACTTAAA CAACCAAAGA TATGAAACTA TCCATGAAGA ACAATATTAT CAATACACAG CAGTCTTTTG TAACCATGCC CAATGTGATT GTACCAGATA TTGAAAAGGA AATACGAAGG ATGGAAAATG GAGCATGCAG CTCCTTTTCT GAGGATGATG ACAGTGCCTC TACATCTGAA GAATCAGAGA ATGAAAACCC TCATGCAAGG GGTTCCTTTA GTTATAAGTC ACTCAGAAAG GGAGGACCAT CACAGAGGGA GCAGTACCTG CCTGGTGCCA TTGCCATTTT TAATGTGAAC AACAGCGACA ATAAGGACCA GGAACCAGAA GAAAAAAAGA

AAAAGAAAAA AGAAAAGAAG AGCAAGTCAG ATGATAAAAA CGAAAATAAA AACGACCCAA AGAAGAAGAT GGAAAAGCGA-3' (FRAG NO J(SEQ ID NO 11883) 5'-ATGGCCAAAG TTCCAGACAT GTTTGAAGAC CTGAAGAACT GTTACAGTGA AAATGAAGAA GACAGTTCCT CCATTGATCA TCTGTCTCTG AATCAGAAAT CCTTCTATCA TGTAAGCTAT GGCCCACTCC ATGAAGGCTG CATGGATCAA TCTGTGTCTC TGAGTATCTC TGAAACCTCT AAAACATCCA AGCTTACCTT CAAGGAGAGC ATGGTGGTAG TAGCAACCAA CGGGAAGGTT CTGAAGAAGA GACGGTTGAG TTTAAGCCAA TCCATCACTG ATGATGACCT GGAGGCCATC GCCAATGACT CAGAGGAAGA AATCATCAAG CCTAGGTCAG CACCTTTTAG CTTCCTGAGC AATGTGAAAT ACAACTTTAT GAGGATCATC AAATACGAAT TCATCCTGAA TGACGCCCTC

AATCAAAGTA TAATTCGAGC CAATGATCAG TACCTCACGG CTGCTGCATT ACATAATCTG GATGAAGCAG TGAAATTTGA CATGGGTGCT TATAAGTCAT CAAAGGATGA TGCTAAAATT ACCGTGATTC TAAGAATCTC AAAAACTCAA TTGTATGTGA CTGCCCAAGA TGAAGACCAA CCAGTGCTGC TGAAGGAGAT GCCTGAGATA CCCAAAACCA TCACAGGTAG TGAGACCAAC CTCCTCTTCT TCTGGGAAAC TCACGGCACT AAGAACTATT TCACATCAGT TGCCCATCCA AACTTGTTTA TTGCCACAAA GCAAGACTAC TGGGTGTGCT TGGCAGGGGG GCCACCCTCT ATCACTGACT TTCAGATACT GGAAAACCAG GCGTAGGTCT GGAGTCTCAC TTGTCTCACT TGTGCAGTGT TGACAGTTCA TATGTACCAT GTACATGAAG AAGCTAAATC CTTTACTGTT AGTCATTTGC TGAGCATGTA CTGAGCCTTG TAATTCTAAA TGAATGTTTA CACTCTTTGT AAGAGTGGAA

CCAACACTAA CATATAATGT TGTTATTTAA AGAACACCCT ATATTTTGCA TAGTACCAAT CATTTTAATT ATTATTCTTC ATAACAATTT TAGGAGGACC AGAGCTACTG ACTATGGCTA CCAAAAAGAC TCTACCCATA TTACAGATGG GCAAATTAAG GCATAAGAAA ACTAAGAAAT ATGCACAATA GCAGTTGAAA CAAGAAGCCA CAGACCTAGG ATTTCATGAT TTCATTTCAA CTGTTTGCCT TCTGCTTTTA AGTTGCTGAT GAACTCTTAA TCAAATAGCA TAAGTTTCTG GGACCTCAGT TTTATCATTT TCAAAATGGA GGGAATAATA CCTAAGCCTT CCTGCCGCAA CAGTTTTTTA TGCTAATCAG GGAGGTCATT TTGGTAAAAT ACTTCTCGAA GCCGAGCCTC AAGATGAAGG CAAAGCACGA AATGTTATTT TTTAATTATT ATTTATATAT GTATTTATAA ATATATTTAA GATAATTATA ATATACTATA TTTATGGGAA CCCCTTCATC CTCTGAGTGT GACCAGGCAT

CCTCCACAAT AGCAGACAGT GTTTTCTGGG ATAAGTAAGT TTGATTTCAT TAATACAGGG CATTTTOGTC CAAGTTGTGC TTATCCCATA GCCAGGAAAC TCTGCATTCT AGTACTTGGG AGACCTGTAA TCATATAATA AATGTACATT AATTACCTTG AGCCAGTAAT TGGTCCGATC TTTGACTCTT TTGCCATTAA ACTTACCTGG GCATTCTTGT TTCATTCAAT TCCACCTGCA ATCAAGTCCT ACAAGCTAAA ATTAGATGAA CTCAACTTTG ACAACCATAG ACCACTGTTA TCAAAACTTT CTTTTCTGGA ATGTAATCAA TGTTTCTTCT AGGTTCTAAA AATTGTGATC AGACCATAAT GTTACATTAT TATCAACAAT AGTGATTGAT AGAGTGTTAT CAGTCATAAC TAAATAAAGC TTGCAAGTGA GGGAGTCATT TCATTGGCGT TTGAGTCAGC AAAGAAGTCA AG-3' (FRAG NO J(SEQ ID NO 11884)

5'-AGCTGCCAGC CAGAGAGGGA GTCATTTCAT TGGCGTTTGA GTCAGCAAAG AAGTCAAGAT GGCCAAAGTT CCAGACATGT TTGAAGACCT GAAGAACTGT TACAGTGAAA ATGAAGAAGA CAGTTCCTCC ATTGATCATC TGTCTCTGAA TCAGAAATCC TTCTATCATG TAAGCTATGG CCCACTCCAT GAAGGCTGCA TGGATCAATC TGTGTCTCTG AGTATCTCTG AAACCTCTAA AACATCCAAG CTTACCTTCA AGGAGAGCAT GGTGGTAGTA GCAACCAACG GGAAGGTTCT GAAGAAGAGA CGGTTGAGTT TAAGCCAATC CATCACTGAT GATGACCTGG AGGCCATCGC CAATGACTCA GAGGAAGAAA TCATCAAGCC TAGGTCATCA CCTTTTAGCr TCCTGAGCAA TGTGAAATAC AACTTTATGA GGATCATCAA ATACGAATTC ATCCTGAATG ACGCCCTCAA TCAAAGTATA ATTCGAGCCA ATGATCAGTA CCTCACGGCT GCTGCATTAC ATAATCTGGA

TGAAGCAGTG AAATTTGACA TGGGTGCTTA TAAGTCATCA AAGGATGATG CTAAAATTAC CGTGATTCTA AGAATCTCAA AAACTCAATT GTATGTGACT GCCCAAGATG AAGACCAACC AGTGCTGCTG AAGGAGATGC CTGAGATACC CAAAACCATC ACAGGTAGTG AGACCAACCT CCTCTTCTTC TGGGAAACTC ACGGCACTAA GAACTATTTC ACATCAGTTG CCCATCCAAA CTTGTTTATT GCCACAAAGC AAGACTACTG GGTGTGCTTG GCAGGGGGGC CACCCTCTAT CACTGACTTT CAGATACTGG AAAACCAGGC GTAGGTCTGG AGTCTCACTT GTCTCACTTG TGCAGTGTTG ACAGTTCATA TGTACCATGT ACATGAAGAA GCTAAATCCT TTACTGTTAG TCATTTGCTG AGCATGTACT GAGCCTTGTA ATTCTAAATG AATGTTTACA CTCTTTGTAA GAGTGGAACC AACACTAACA TATAATGTTG TTATTTAAAG AACACCCTAT ATTTTGCATA GTACCAATCA TTTTAATTAT TATTCTTCAT AACAATTTTA GGAGGACCAG AGCTACTGAC TATGGCTACC AAAAAGACTC TACCCATATT ACAGATGGGC AAATTAAGGC ATAAGAAAAC TAAGAAATAT GCACAATAGC AGTCGAAACA AGAAGCCACA GACCTAGGAT TTCATGATTT CATTTCAACT GTTTGCCTTC TGCTTTTAAG TTGCTGATGA ACTCTTAATC AAATAGCATA AGTTTCTGGG ACCTCAGTTT TATCATTTTC AAAATGGAGG GAATAATACC TAAGCCTTCC TGCCGCAACA GTTTTTTATG CTAATCAGGG AGGTCATTTT GGTAAAATAC TTCTCGAAGC CGAGCCTCAA GATGAAGGCA AAGCACGAAA TGTTATTTTT TAATTATTAT TTATATATGT ATTTATAAAT ATATTTAAGA TAATTATAAT

ATACTATATT TATGGGAACC CCTTCATCCT CTGAGTGTGA CCAGGCATCC TCCACAATAG CAGACAGTGT TTTCTGGGAT AAGTAAGTTT GATTTCATTA ATACAGGGCA TΓTTGGΓCCA AGTTGTGCTT ATCCCATAGC CAGGAAACΓC TGCATTCTAG TACTTGGGAG ACCTGTAATC ATATAATAAA TGTACATTAA TTACCΓTGAG CCAGTAATΓG GTCCGATCTT TGACTCTTTT GCCATTAAAC TTACCTGGGC ATTCTTGTTT CATTCAATTC CACCTGCAAT CAAGTCCTAC AAGCTAAAAT TAGATGAACT CAACTTTGAC AACCATGAGA CCACTGTTAT CAAAACTTTC TTTTCTGGAA TGTAATCAAT GTTTCTTCTA GGTTCTAAAA ATTGTGATCA GACCATAATG TTACATTATT ATCAACAATA GTGATTGATA GAGTGTTATC AGTCATAACT AAATAAAGCT TGCAACAAAA TTCTCTG-3' (FRAG NO J(SEQ DD NO 11885)

Human Interleukin-1 Receptor (IL-1 R) Nucleic Acids and Anti-sense Oligonucleotide Fragments

5*-GCCACGTGCT GCTGGGTCTC AGTCCTCCAC TTCCCGTGTC CTCTGGAAGT TGTCAGGAGC AATGTTGCGC TTGTACGTGT TGGTAATGGG AGTTTCTGCC TTCACCCTTC AGCCTGCGGC ACACACAGGG GCTGCCAGAA GCTGCCGGTT TCGTGGGAGG CATTACAAGC GGGAGTTCAG GCTGGAAGGG GAGCCTGTAG CCCTGAGGTG CCCCCAGGTG CCCTACTGGT TGTGGGCCTC TGTCAGCCCC CGCATCAACC TGACATGGCA TAAAAATGAC TCTGCTAGGA CGGTCCCAGG AGAAGAAGAG ACACGGATGT GGGCCCAGGA CGGTGCTCTG TGGCTTCTGC CAGCCTTGCA GGAGGACTCT GGCACCTACG TCTGCACTAC TAGAAATGCT TCTTACTGTG ACAAAATGTC CATTGAGCTC

AGAGTTTTTG AGAATACAGA TGCTTTCCTG CCGTTCATCT CATACCCGCA AATTTTAACC TTGTCAACCT CTGGGGTATT AGTATGCCCT GACCTGAGTG AATTCACCCG TGACAAAACT GACGTGAAGA TTCAATGGTA CAAGGATTCT CTTCTTTTGG ATAAAGACAA TGAGAAATTT CTAAGTGTGA GGGGGACCAC TCACTTACTC GTACACGATG TGGCCCTGGA AGATGCTGGC TATTACCGCT GTGTCCTGAC ATTTGCCCAT GAAGGCCAGC AATACAACAT CACTAGGAGT ATTGAGCTAC GCATCAAGAA AAAAAAAGAA GAGACCATTC CTGTGATCAT TTCCCCCCTC AAGACCATAT CAGCTTCTCT GGGGTCAAGA CTGACAATCC CGTGTAAGGT GTTTCTGGGA ACCGGCACAC CCTTAACCAC CATGCTGTGG TGGACGGCCA ATGACACCCA CATAGAGAGC GCCTACCCGG GAGGCCGCGT GACCGAGGGG CCACGCCAGG AATATTCAGA AAATAATGAG

AACTACATTG AAGTGCCATT GATTTTTGAT CCTGTCACAA GAGAGGATTT GCACATGGAT TTTAAATGTG TTGTCCATAA TACCCTGAGT TTTCAGACAC TACGCACCAC AGTCAAGGAA GCCTCCTCCA CGTTCTCCTG GGGCATTGTG CTGGCCCCAC TTTCACTGGC CTTCTTGGTT TTGGGGGGAA TATGGATGCA CAGACGGTGC AAACACAGAA CTGGAAAAGC AGATGGTCTG ACTGTGCTAT GGCCTCATCA TCAAGACTTT CAATCCTATC CCAAGTGAAA TAAATGGAAT GAAATAATTC AAACACAAAA AAAAAAAAAA AAAAAAAA GCCGGAGCCG ACTCGGAGCG CGCGGCGCGG CCGGGAGGAG CCGAGCGCGC CGGGCGCGGC GTGGGGGCGC CGGCTGCCCC GCGCGCCCAG GGAGCGGCAG GAATGTGACA ATCGCGCGCC CGCACCGTAG CACTCCTCGC TCGGCTCCTA GGGCTCTCGC CCTCTGAGCT GAGCCGGGTT CCGCCCGGGC TGGGATCCCA

TCACCCTCCA CGGCCGTCCG TCCAGGTAGA CGCACCCTCT GAAGATGGTG ACTCCCTCCT GAGAAGCTGG ACCCCTTGGT AAAAGACAAG GCCTTCTCCA AGAAGAATAT GAAAGTGTTA CTCAGACTTA TTTGTTTCAT AGCTCTACTG ATTTCTTCTC TGGAGGCTGA TAAATGCAAG GAACGTGAAG AAAAAATAAT TTTAGTGTCA TCTGCAAATG AAATTGATGT TCGTCCCTGT CCTCTTAACC CAAATGAACA CAAAGGCACT ATAACTTGGT ATAAAGATGA CAGCAAGACA CCTGTATCTA CAGAACAAGC CTCCAGGATT CATCAACACA AAGAGAAACT TTGGTTTGTT CCTGCTAAGG TGGAGGATTC AGGACATTAC TATTGCGTGG TAAGAAATTC ATCTTACTGC CTCAGAATTA AAATAAGTGC AAAATTTGTG GAGAATGAGC CTAACTTATG TTATAATGCA CAAGCCATAT TTAAGCAGAA ACTACCCGTT GCAGGAGACG GAGGACTTGT GTGCCCTTAT ATGGAGTTTT

TTAAAAATGA AAATAATGAG TTACCTAAAT TACAGTGGTA TAAGGATTGC AAACCTCTAC TTCTTGACAA TATACACTTT AGTGGAGTCA AAGATAGGCT CATCGTGATG AATGTGGCTG AAAAGCATAG AGGGAACTAT ACTTGTCATG CATCCTACAC ATACTTGGGC AAGCAATATC CTATTACCCG GGTAATAGAA TTTATTACTC TAGAGGAAAA CAAACCCACA AGGCCTGTGA TTGTGAGCCC AGCTAATGAG ACAATGGAAG TAGACTTGGG ATCCCAGATA CAATTGATCT GTAATGTCAC CGGCCAGTTG AGTGACATTG CTTACTGGAA GTGGAATGGG TCAGTAATTG ATGAAGATGA CCCAGTGCTA GGGGAAGACT ATTACAGTGT GGAAAATCCT GCAAACAAAA GAAGGAGTAC CCTCATCACA GTGCTTAATA TATCGGAAAT TGAAAGTAGA TTTTATAAAC ATCCATTTAC CTGTTTTGCC AAGAATACAC ATGGTATAGA TGCAGCATAT ATCCAGTTAA TATATCCAGT

CACTAATTTC CAGAAGCACA TGATTGGTAT ATGTGTCACG TTGACAGTCA TAATTGTGTG TTCTGTTTTC ATCTATAAAA TCTTCAAGAT TGACATTGTG CTTTGGTACA GGGATTCCTG CTATGATTTT CTCCCAATAA AAGCTTCAGA TGGAAAGACC TATGACGCAT ATATACTGTA TCCAAAGACT GTTGGGGAAG GGTCTACCTC TGACTGTGAT ATTTTTGTGT TTAAAGTCTT GCCTGAGGTC TTGGAAAAAC AGTGTGGATA TAAGCTGTTC ATTTATGGAA GGGATGACTA CGTTGGGGAA GACATTGTTG AGGTCATTAA TGAAAACGTA AAGAAAAGCA GAAGACTGAT TATCATTTTA GTCAGAGAAA CATCAGGCTT CAGCTGGCTG GGTGGTTCAT CTGAAGAGCA AATAGCCATG TATAATGCTC TTGTTCAGGA TGGAATTAAA GTTGTCCTGC TTGAGCTGGA GAAAATCCAA GACTATGAGA AAATGCCAGA ATCGATTAAA TTCATTAAGC AGAAACATGG GGCTATCCGC

TGGTCAGGGG ACTTTACACA GGGACCACAG TCTGCAAAGA CAAGGTTCTG GAAGAATGTC AGGTACCACA TGCCAGTCCA GCGACGGTCA CCTTCATCTA AACACCAGTT ACTGTCACCA GCCACTAAGG AGAAACTGCA AAGAGAGGCT CACGTGCCTC TCGGGTAGCA TGGAGAAGTT GCCAAGAGTT CTTTAGGTGC CTCCTGTCTT ATGGCGTTGC AGGCCAGGTT ATGCCTCATG CTGACTTGCA GAGTTCATGG AATGTAACTA TATCATCCTT TATCCCTGAG GTCACCAGGA ATCAGG-3' (FRAG NO J(SEQ DD NO 11889) 5'-GCCACGTGCT GCTGGGTCTC AGTCCTCCAC TTCCCGTGTC CTCTGGAAGT TGTCAGGAGC AATGTTGCGC TTGTACGTGT TGGTAATGGG AGTTTCTGCC TTCACCCTTC AGCCTGCGGC ACACACAGGG GCTGCCAGAA GCTGCCGGTT TCGTGGGAGG CATTACAAGC GGGAGTTCAG GCTGGAAGGG GAGCCTGTAG CCCTGAGGTG

CCCCCAGGTG CCCTACTGGT TGTGGGCCTC TGTCAGCCCC CGCATCAACC TGACATGGCA TAAAAATGAC TCTGCTAGGA CGGTCCCAGG AGAAGAAGAG ACACGGATGT GGGCCCAGGA CGGTGCTCTG TGGCTTCTGC CAGCCTTGCA GGAGGACTCT GGCACCTACG TCTGCACTAC TAGAAATGCT TCTTACTGTG ACAAAATGTC CATTGAGCTC AGAGTTTTTG AGAATACAGA TGCTTTCCTG CCGTTCATCT CATACCCGCA AATTTTAACC TTGTCAACCT CTGGGGTATT AGTATGCCCT GACCTGAGTG AATTCACCCG TGACAAAACT GACGTGAAGA TTCAATGGTA CAAGGATTCT CTTCTTTTGG ATAAAGACAA TGAGAAATTT CTAAGTGTGA GGGGGACCAC TCACTTACTC GTACACGATG TGGCCCTGGA AGATGCTGGC TATTACCGCT GTGTCCTGAC ATTTGCCCAT GAAGGCCAGC AATACAACAT CACTAGGAGT ATTGAGCTAC GCATCAAGAA AAAAAAAGAA

GAGACCATTC CTGTGATCAT TTCCCCCCTC AAGACCATAT CAGCTTCTCT GGGGTCAAGA CTGACAATCC CGTGTAAGGT GTTTCTGGGA ACCGGCACAC CCTTAACCAC CATGCTGTGG TGGACGGCCA ATGACACCCA CATAGAGAGC GCCTACCCGG GAGGCCGCGT GACCGAGGGG CCACGCCAGG AATATTCAGA AAATAATGAG AACTACATTG AAGTGCCATT GATTTTTGAT CCTGTCACAA GAGAGGATTT GCACATGGAT TTTAAATGTG TTGTCCATAA TACCCTGAGT TTTCAGACAC TACGCACCAC AGTCAAGGAA GCCTCCTCCA CGTTCTCCTG GGGCATTGTG CTGGCCCCAC TTTCACTGGC CTTCTTGGTT TTGGGGGGAA TATGGATGCA CAGACGGTGC AAACACAGAA CTGGAAAAGC AGATGGTCTG ACTGTGCTAT GGCCTCATCA TCAAGACTTT CAATCCTATC CCAAGTGAAA TAAATGGAAT GAAATAATTC AAACACAAAA AAAAAAAAAA

AAAAAAAA-3' (FRAG NO J(SEQ ID O 11887)

5'-GCCGGAGCCG ACTCGGAGCG CGCGGCGCGG CCGGGAGGAG CCGAGCGCGC CGGGCGCGGC GTGGGGGCGC CGGCTGCCCC GCGCGCCCAG GGAGCGGCAG GAATGTGACA ATCGCGCGCC CGCACCGTAG CACTCCTCGC TCGGCTCCTA GGGCTCTCGC CCTCTGAGCT GAGCCGGGTT CCGCCCGGGC TGGGATCCCA TCACCCTCCA CGGCCGTCCG TCCAGGTAGA CGCACCCTCT GAAGATGGTG ACTCCCTCCT GAGAAGCTGG ACCCCTTGGT AAAAGACAAG GCCTTCTCCA AGAAGAATAT GAAAGTGTTA CTCAGACTTA TTTGTTTCAT AGCTCTACTG ATTTCTTCTC TGGAGGCTGA TAAATGCAAG GAACGTGAAG AAAAAATAAT TTTAGTGTCA TCTGCAAATG AAATTGATGT

TCGTCCCTGT CCTCTTAACC CAAATGAACA CAAAGGCACT ATAACTTGGT ATAAAGATGA CAGCAAGACA CCTGTATCTA CAGAACAAGC CTCCAGGATT CATCAACACA AAGAGAAACT TTGGTTTGTT CCTGCTAAGG TGGAGGATTC AGGACATTAC TATTGCGTGG TAAGAAATTC ATCTTACTGC CTCAGAATTA AAATAAGTGC AAAATTTGTG GAGAATGAGC CTAACTTATG TTATAATGCA CAAGCCATAT TTAAGCAGAA ACTACCCGTT GCAGGAGACG GAGGACTTGT GTGCCCTTAT ATGGAGTTTT TTAAAAATGA AAATAATGAG TTACCTAAAT TACAGTGGTA TAAGGATTGC AAACCTCTAC TTCTTGACAA TATACACTTT AGTGGAGTCA AAGATAGGCT CATCGTGATG AATGTGGCTG AAAAGCATAG AGGGAACTAT ACTTGTCATG CATCCTACAC ATACTTGGGC AAGCAATATC CTATTACCCG GGTAATAGAA TTTATTACTC TAGAGGAAAA CAAACCCACA

AGGCCTGTGA TTGTGAGCCC AGCTAATGAG ACAATGGAAG TAGACTTGGG ATCCCAGATA CAATTGATCT GTAATGTCAC CGGCCAGTTG AGTGACATTG CTTACTGGAA GTGGAATGGG TCAGTAATTG ATGAAGATGA CCCAGTGCTA GGGGAAGACT ATTACAGTGT GGAAAATCCT GCAAACAAAA GAAGGAGTAC CCTCATCACA GTGCTTAATA TATCGGAAAT TGAAAGTAGA TTTTATAAAC ATCCATTTAC CTGTTTTGCC AAGAATACAC ATGGTATAGA TGCAGCATAT ATCCAGTTAA TATATCCAGT CACTAATTTC CAGAAGCACA TGATTGGTAT ATGTGTCACG TTGACAGTCA TAATTGTGTG TTCTGTTTTC ATCTATAAAA TCTTCAAGAT TGACATTGTG CTTTGGTACA GGGATTCCTG CTATGATTTT CTCCCAATAA AAGCTTCAGA TGGAAAGACC TATGACGCAT ATATACTGTA TCCAAAGACT GTTGGGGAAG GGTCTACCTC TGACTGTGAT ATTTTTGTGT

TTAAAGTCTT GCCTGAGGTC TTGGAAAAAC AGTGTGGATA TAAGCTGTTC ATTTATGGAA GGGATGACTA CGTTGGGGAA GACATTGTTG AGGTCATTAA TGAAAACGTA AAGAAAAGCA GAAGACTGAT TATCATTTTA GTCAGAGAAA CATCAGGCTT CAGCTGGCTG GGTGGTTCAT CTGAAGAGCA AATAGCCATG TATAATGCTC TTGTTCAGGA TGGAATTAAA GTTGTCCTGC TTGAGCTGGA GAAAATCCAA GACTATGAGA AAATGCCAGA ATCGATTAAA TTCATTAAGC AGAAACATGG GGCTATCCGC TGGTCAGGGG ACTTTACACA GGGACCACAG TCTGCAAAGA CAAGGTTCTG GAAGAATGTC AGGTACCACA TGCCAGTCCA GCGACGGTCA CCTTCATCTA AACACCAGTT ACTGTCACCA GCCACTAAGG AGAAACTGCA AAGAGAGGCT CACGTGCCTC TCGGGTAGCA TGGAGAAGTT GCCAAGAGTT CTTTAGGTGC CTCCTGTCTT ATGGCGTTGC AGGCCAGGTT

ATGCCTCATG CTGACTTGCA GAGTTCATGG AATGTAACTA TATCATCCTT TATCCCTGAG GTCACCAGGA ATCAGG-3' (FRAG NO _)(SEQ ID NO 11888)

Human Interleukin-8 Fragments Antisense Oligonucleotide Fragments

5'-GBTGTTTGTT BCCBBBGCBT CBBGBBTBGC TTTGCTBTCT BBGGBTCBCB TTTBGBCBTB GGBBBBCGCT GTBGGTCBGBB BGBTGTGCTT BCCTTCBCBC BGBGCTGCBG

BBBTCBGGBBGG CTGCCBBGBGBG CCBCGGCCBGC TTGGBGTCBT GTTTBCBCBC BGTGBGGTGC TCCGGTGGCT TTTTGCTTGT GTGCTCTGCT GTCTCTG TTC CTTCCGGTGG TTTCTTCCTG GCTCTTGTCC TTTCTCTTGG CCCTTGGCCC-3' (FRAG NO 1834) (SEQ ID NO 11216)

5'-G CTC CGG-3' (FRAG NO 1835) (SEQ ED NO 11217)

5'-CBBGBBTBGC-3' (FRAG NO 1836) (SEQ ID NO 11218)

5'-CBCBC BGTGBGGTGC-3' (FRAG NO 1837) (SEQ DD NO 11219)

5'-BCCBBBGCBT CBBGBBTBGC-3' (FRAG NO 1838) (SEQ DD NO 11220) 5' GCCBBGBGBG CCBCGGCCBGC-3' (FRAG NO 1839) (SEQ ID NO 11221)

5'-GTG CTC CGG TGG CTT TTT-3' (FRAG NO 1289)(SEQ DD NO 10667)

5'-GCT TGT GTG CTC TGC TGT CTC TG-3' (FRAG NO I290)(SEQ ID NO 10668)

5'-'TTC CTT CCG GTG GTT TCT TCC TGG CTC TTG TCC T-3' (FRAG NO 1291)(SEQ ID NO 10669)

5'-TTC TCT TGG CCC TTG GCC C-3' (FRAG NO 1292)(SEQ ID NO 10670) 5'-GBTGTTTGTT BCCBBBGCBT CBBGBBTBGC TTTGCTBTCT BBGGBTCBCB TTTBGBCBTB GGBBBBCGCT GTBGGTCBGBB BGBTGTGCTT BCCTTCBCBC BGBGCTGCBG

BBBTCBGGBBGG CTGCCBBGBGBG CCBCGGCCBGC TTGGBGTCBT GTTTBCBCBC BGTGBGGTGC TCCGGTGGCT TTTTGCTTGT-3' (FRAG NO 1840) (SEQ ID NO 11222)

Human IL-8 Receptor Alpha Antisense Oligonucleotide Fragments

5'-ACAGGGGCTG TAATCTTCATC TGCAGGTGGC ATGCCAGTGA AATTTAGATC ATCAAAATCC CACATCTGTG GATCTGTAAT ATTTGACATG TCCTCTTCAG TTTCAGCAAT GGTTTGATCT AACTGAAGCA CCGGCCAGGB CBGGGGCTGT BBTCTTCBTC TGCBGGTGGC BTGCCBGTGB BBTTTBGBTC BTCBBBBTCC CBCBTCTGTG GBTCTGTBBT BTTTGBCBTG TCCTCTTCBG TTTCBGCBB TGGTTTGBTC TBBCTGBBGC BCCGGCCBGG TGGCTCGGTG CTTCTGCCCG TGTTGTTGCG GCGCTCGGTT

GGTGTGGCCC CTGTGGTGCT TCGTTTCCCC CTCTTTCTCT TTGTTCGGGG GTTCTTGTGG CGGGCTGCTT GTCTCGTTCC-3'(FRAG NO 1841)(SEQ ID NO 11223) 5'-CBGGGGC-3' (FRAG NO 1842) (SEQ ID NO 11224) 5'-GCBGGTGGC-3' (FRAG NO 1843) (SEQ ID NO 11225) 5' GCGGCGCTC-3' (FRAG NO 1844) (SEQ DD NO 11226) 5'-TGGCTCGGTGCTTCTGCCCC (FRAG NO 1293)(SEQ DD NO 10671) 5' TGTTGTTGCGGCGCTC (FRAG NO 1294)(SEQ ID NO 10672) 5'-GGTTGGTGTGGCCCCTG (FRAG NO 1295)(SEQ IDNO 10673) 5'-TGGTGCTTCGTTTCC (FRAG NO 1296)(SEQ DD NO 10674)

5'-CCCTCTTTCTCTTTGTTC (FRAG NO 1297)(SEQ ID NO 10675) 5 GGGGGTTCTTGTGGC (FRAG NO 1298)(SEQ DD NO 10676) 5'-GGGCTGCTTGTCTCGTTCC (FRAG NO 1299)(SEQ ID NO 10677)

5'-ACAGGGGCTG TAATCTTCATC TGCAGGTGGC ATGCCAGTGA AATTTAGATC ATCAAAATCC CACATCTGTG GATCTGTAAT ATTTGACATG TCCTCTTCAG TTTCAGCAAT GGTTTGATCT AACTGAAGCA CCGGCCAGG 3' (FRAG NO 1845) (SEQ ED NO 11227)

5' B CBGGGGCTGT BBTCTTCBTC TGCBGGTGGC BTGCCBGTGB BBTTTBGBTC BTCBBBBTCC CBCBTCTGTG GBTCTGTBBT BTTTGBCBTG TCCTCTTCBG TTTCBGCBB TGGTTTGBTC TBBCTGBBGC BCCGGCCBGG-3' (FRAG NO 1846) (SEQ DD NO 11228)

Interleukin- 1 1 (IL-11) Nucleic Acid and Antisnese Oligonucleotide Fragments

S'-GCTCAGGGCA CATGCCTCCC CTCCCCAGGC CGCGGCCCAG CTGACCCTCG GGGCTCCCCC GGCAGCGGAC AGGGAAGGGT TAAAGGCCCC CGGCTCCCTG CCCCCTGCCC TGGGGAACCC CTGGCCCTGT GGGGACATGA ACTGTGTTTG CCGCCTGGTC CTGGTCGTGC TGAGCCTGTG GCCAGATACA GCTGTCGCCC CTGGGCCACC

ACCTGGCCCC CCTCGAGTTT CCCCAGACCC TCGGGCCGAG CTGGACAGCA CCGTGCTCCT GACCCGCTCT CTCCTGGCGG ACACGCGGCA GCTGGCTGCA CAGCTGAGGG ACAAATTCCC AGCTGACGGG GACCACAACC TGGATTCCCT GCCCACCCTG GCCATGAGTG CGGGGGCACT GGGAGCTCTA CAGCTCCCAG GTGTGCTGAC AAGGCTGCGA GCGGACCTAC TGTCCTACCT GCGGCACGTG CAGTGGCTGC GCCGGGCAGG TGGCTCTTCC CTGAAGACCC TGGAGCCCGA GCTGGGCACC CTGCAGGCCC GACTGGACCG GCTGCTGCGC CGGCTGCAGC TCCTGATGTC CCGCCTGGCC CTGCCCCAGC CACCCCCGGA CCCGCCGGCG CCCCCGCTGG CGCCCCCCTC CTCAGCCTGG GGGGGCATCA GGGCCGCCCA CGCCATCCTG GGGGGGCTGC ACCTGACACT TGACTGGGCC GTGAGGGGAC TGCTGCTGCT GAAGACTCGG CTGTGACCCG GGGCCCAAAG CCACCACCGT

CCTTCCAAAG CCAGATCTTA TTTATTTATT TATTTCAGTA CTGGGGGCGA AACAGCCAGG TGATCCCCCC GCCATTATCT CCCCCTAGTT AGAGACAGTC CTTCCGTGAG GCCTGGGGGA CATCTGTGCC TTATTTATAC TTATTTATTT CAGGAGCAGG GGTGGGAGGC AGGTGGACTC CTGGGTCCCC GAGGAGGAGG GGACTGGGGT CCCGGATTCT TGGGTCTCCA AGAAGTCTGT CCACAGACTT CTGCCCTGGC TCTTCCCCAT CTAGGCCTGG GCAGGAACAT ATATTATTTA TTTAAGCAAT TACTTTTCAT GTTGGGGTGG GGACGGAGGG GAAAGGGAAG CCTGGGTTTT TGTACAAAAA TGTGAGAAAC CTTTGTGAGA CAGAGAACAG GGAATTAAAT GTGTCATACA TATCC CAGCTGCGGC ATCCTCTGTC TCAGAGTCTT GGTGTCTCTG TTCCTTTCCC CTCGGGGTCT CCCTGGGTCT CCCCAAGTCC CTCCTGCTGT CTTCCTCCCG CTCTCTGATC TCTGACTCCC

AGAACCTCTC CCTCTGTCTC CAGGGCTGCC CCTCTGATCC TCTTTGCTTC TCTGGTGTGT CTCTCTGGCT GCCTCCATCT CTGTGGATCT CCGTCTCCCT GTCTCTGTCT CAGTCTGTCC TTCACTCTGT GTGTGTGTGT GTCTCTCTCT CTCTCTCTCC TTCCCTTCCA CTCCCTCTTC CTCCTGCCTC CACCTCTCCA GGCCCCTGTC TTGTCCCTCC GTCCGGCCTT TCTCTGCCTT TCCGTCCTCC TGCCTCCCCA TCTCTCTCTG CTAGTCCTGT CCAGCCGGAC CCCCACCCAC AGTCGGGCCC CAGCGCTTGA GCCTGAGTGT CTGCTCCGGC CCGTGGAGGT GGAGGGAGGG GACGCCAATG ACCTCACCAG CCCCTCTCCG ACCACCCCCC CCTTTCCCTT TTCAACTTTT CCAACTTTTC CTTCCGTGCC CTCCTCCGAG CGCGGCGGCG TGAGCCCTGC AAGGCAGCCG CTCCGTCTGA ATGGAAAAGG CAGGCAGGGA GGGTGAGTCA GGATGTGTCA GGCCGGCCCT

CCCCTGCCGC CTGCCCCCCG CCCGCCCGCC CCAGGCCCCC TATATAACCC CCCAGGCGTC CACACTCCCT CACTGCCGCG GGCCCTGCTG CTCAGGGCAC ATGCCTCCCC TCCCCAGCCG CGGGCCCAGC TGACCCTCGG GGCTCCCCCG GCAGCGGACA GGGAAGGGTT AAAGGCCCCC GGCTCCCTGC CCCCTGCCCT GGGGAACCCC TGGCCCTGTG GGGACATGAA CTGTAAGTTG GTTCATGGGG AGGGTGGAGG GGACAGGGAG GCAGGGAGGA GAGGGACCCA CGGCGGGGGT GGGAGCAGAC CCCGCTGAGT CGCACAGAGA GGGACCCGGA GACAGGCAGC CGGGGAGGAG AGCAGCTTCG GAGACAGGAG GCGGCGGAGG AGATGGGCAG AGAGAGACAC AGACAGGAGC GGATGGAGGC AGCCAATCAG AGGCGCCGCA GGAGGGACGG GCCAGACAGG GCCCGAGAGG AGCGAGACGC GAGACCGAGC AGGGGCAGGG ACGCAGGGAC

TGGTGCCGGG AGGGAGGTGA CCCCCATCGA CCCAGGCCCC AGGGAGCCCG CGGGGACCGG GAGACTCCCT GGGATTCCGG CAGAGAGGCT CCGGAGGGAA ACTGAGGCAG GGTCCGCGGA GAGCGGAGCA AGCCAGGGAG TAGCGACCCC AGCCGGGGGG AGGAGAGAGA CTGGGCGCCG GGGGAAAGCG GGGAGAGCCG GGCAGATGCG GCCGACGGAG GCGCGGACAG ACCGACGGCT GGCGGGCCCG GGGGGCGGGC TGGGGGTGTG CGAGGCGCGG GCGGCCGGGG AGCGCTGATT GGCTGGCGGG TGGCCGGGTG GGCGGGGCGG CCGGGGTGGG CTGCGGGGAG CGAGCTCCGG ACCCCCGCGC CCCCGGCGCC CCCCGCGCCC CCCGCCGCCA GCTCTCCCGC TCCCGGCGCC CGGCCGGGCC ATGGCTCTGC CCCTCTCCGC CCAGGTGCGC TGCGGCCCGG GCTTCTGCCG CCCACCCGGC GGGCTCCTGG GAGGGCGTCT

AAGGGGTCTC CCGTGGGAGA GGTCCGTGTC TCCCGGACTC CGTCCTGGGC TTTTGGCTCC TTCCCCTGCT CCCAGCCAGC TCGGGCTCCC GCGGCCCGGG GAGGGGGCAG GTTCTGGCCT GTGCCTCCCC CACCATCCGC GCCCCGGGGC CCAGATTCCG GCGTCCGGGG GCGGACGGGA GACGCCCGGG CCGCGTCTGC TCCGACGGGC GGGGCAGCCA GAGCCAGGGA GGGAGAGGGA AGCCCGCCTG GCCCTGCGAC CTGCCCGCGG GCGTTCCACC CTGGGACTTA AGACCTCCAG CTCCATCCTC CCTAAGGCCG GGAGTCCAGG CCCCAGACCC TCCTCCCCGA GACCCAGGAG TCCAGACCCC AGGCCTTCCT CCCTCAGACC TAGGAGTCCA GGCCCCCAGC CTCTCCTCCC TCAGACCCAG GAGGAGTCCA GACCCCAGTT CCTCCTCCCT CAGACCCGGG AGTCCAGCGC AGGCCCTCCT CTCTCAGACC CGGAGTCCAG CCTGAGCTCT CTGCCTTATC CTGCCCCCAG GTGTTTGGCG

CCTGGTCCTG GTCGTGCTGA GCCTGTGGCC AGATACAGCT GTCGCCCCTG GGCCACCACC TGGCCCCCCT CGAGTTTCCC CAGACCCTCG GGCCGAGCTG GACAGCACCG TGCTCCTGAC CCGCTCTCTC CTGGCGGACA CGCGGCAGCT GGCTGCACAG CTGGTAGGAG AGACTGGGCT GGGGCCAGCA CAGGAGTGAG AGGCAGAGAG GAACGGAGAG GAGTCTGCGG GCAGCCACTT GGAGGGGTTC TGGGCTCTCA GGTGGCAGAG TGAGGGAGGG GAAGAGTTGG GGGCCTGGCG TGGGGGATGG AGGGAGCCCC GAGGCTGGGC AGGGGCCACC TCACAGCTTT TTTCCCTGCC AGAGGGACAA ATTCCCAGCT GACGGGGACC ACAACCTGGA TTCCCTGCCC ACCCTGGCCA TGAGTGCAGG GGCACTGGGA GCTCTACAGG TAAGGGCAAG GGAGTGGGCT GGGGACAAGG TGGGAGGCAG GCAGTGAAGG GGGCGGGGAG GATGAGGGGC

ACTGGTCGGG TGTTCTCTGA TGTCCCGGCT CTATCCCCAG CTCCCAGGTG TGCTGACAAG GCTGCGAGCG GACCTACTGT CCTACCTGCG GCACGTGCAG TGGCTGCGCC GGGCAGGTGG CTCTTCCCTG AAGACCCTGG AGCCCGAGCT GGGCACCCTG CAGGCCCGAC TGGACCGGCT GCTGCGCCGG CTGCAGCTCC TGGTATGTCC TGGCCCCAAG ACCTGACACC CCAGACCCCC ACCCCTGGCC CCAAAATCCT GTGGCCTGAG TCCTTGAAGC CTGAGACCCC AGACCCGAGT GCAACAGCCC CGCTCTGAGA CCCTGACACC CTAACAGCCC GCTCTGAGAC CCTGACACCG TAACAGCCCC GCTCTGAGAC CCTGACCCTA ACAGTCCTGC TCTGAGACCC TGACCCTGCA GTCCCAAGAT CCTGTGGCCC TGAGACCCTG AGGCCCTAGA CCCCCAAATC CTGCCCAGAA ACTTCAAATT CTCACCCAAG ACCCTGAGAC TCCATCATCC ATGACCTCAA AGTCCCCAGA TCCCAGCCCC

TAAGACCCAA GACCCCATCC TGAAGCCCAA AGCCTTGAGA ATTCAAATCC TCACCTCAAG ACTTGGAGAC CCTGGCCCCA TGACATTGAA AACCATGGAC CTGGCCAGGC GTGGTGGCTC ACGCCTGTAA TCCCAGCACT TTGGGAGGCC GAGGCAAGTG GATCACCTGA GGTCGGGAGT TCAAGACCAG CCAGACCAAC ATGGTGAAAC CCTGTCTCTA CTAAAAATAC AAAATTAGCC AGGCGTGGTG GTGCATGCCT GTAATCCCAG CTACTTGGGA GGCTGAGGCA GGAGAATCGC TTGAACCTGG GAGGCGGAGG TTGCAGTGAG CCGAGATCGC ACCATTACAC TCCAGCCTGG GCAACAAGAG CAAAACTCCC TCTCTCTCAA AAAAAAAAAA AAAAAAAAAA AAGAAGGAAA AGAAAACCAT GGACCTCCAG ACCCTGAGAC CCCAGGCCCC AGCCCTGAGA TCCTGACATC TTAAAGATCC CAGGCCCTAA GATACAAGAC CTTGACCCAA AGCCAGCCTT

GGGACCCTGG CTGTACAAAC CCAAGACCTC CAGGACCTAG ACCCCGAGCC CTGAGGCCCT ATGTCTCACT CCCAACATCG AAAACCCTGA CACCTCAGAT CCTGAGCCTG CGCCTGTACG ACTCCAAGAC CCTCACTTCC AAAGCCAGGC CCAAAGCCCT GAGACCAGAA GACTTCAAAC CCTGGTTCTT GGGCCTAACT CCAAAGACCC TGGATCTCAA ATTCCAACTT CTAGCTCTGA GACTCCAGCC CTCACCCATG AGTTCCTGAA CTTGAACCCA GAGACCCCAT CTCTAAGACT TCAGCCTTGA GATCCAGGGC CTGACCCTAG ACTCGAGCCC ACAGACCTCA GATACTGTCT GTAAAACCCC AGCTCTGGTG GGGAGCAGTG GCTCACTCCT GTAATCCCAA GGCAGGGGAG GCCAAGGCAG AAGGACCTCT TGAGGCCATG AGTTTGAGAC AGCCTGGGCA GCATAGCAAG ACTCTGTTTC TTAATTATTA TTATTATTAT TATTTTTTGG AGACAGAGTC TCGCGCTCTG TTGCCCAGGC

TAGAGTGCAA TGGTGCCATT TCGGCTTGCT GGAACCTCCG CCTCCTGGGC TCAAGCGATT CTCCTGCCTC AGCCTCCTGA GTAGCTGGGA CTTCAGGTGC ACACTGCCAC ACCCGGATAA TTTTTTTGTA TTTTAGTAGA CACAGGGTTT CACCGTGTTG CCCAGGCTGG TCACAAACTC CTGAGCTCAG GCCATCCGCC CGCCTCGGCC TCCCAAAGCG CTGGGATAAC AGGCGTGACG CCGCGCCTGG CTTCTTAATT GTTCTAACAG CAGCGACAAC AACAAAAACC CAGCTCTGAG ATTCCAGCCC CGGCGACTCT AACAGTCCCA GGCCCGATCC CTCACCTAGA ACCGAGATGC CAGCCCTGAC TCCACAGACT TCACCCCCAA CCCCCACACT CAGCTCTGGA AGCCCGTCCT GACTCCAGCC TCCATTTTCG GAACCCCACA GCCTGAAGAG CTCCCGGCCT AAACACTTCA CCCCACGCGC CACAGTCCCC CTGTGAATAT GCAGCCCCGA TTCAGCTGCA GCTCCACAGC ACCCCTGCCC

TGCACCCCCG CTGCACCCCC TACCTGTGAC TCACCTCTCT CCTCTCCCCA CAGATGTCCC GCCTGGCCCT GCCCCAGCCA CCCCCGGACC CGCCGGCGCC CCCGCTGGCG ccccccTCcr GCCGCCCACG CCATCCTGGG GGGGCTGCAC CTGACACTTG ACTGGGCCGT CTGCTGCTGA AGACTCGGCT GTGACCCGGG GCCCAAAGCC ACCACCGTCC TTCCAAAGCC AGATCTTATT TATTTATTTA TTTCAGTACT GGGGGCGAAA CAGCCAGGTG ATCCCCCCGC CATTATCTCC CCCTAGTTAG AGACAGTCCT TCCGTGAGGC CTGGGGGGCA TCTGTGCCTT ATTTATACTT ATTTATTTCA GGAGCAGGGG TGGGAGGCAG GTGGACTCCT GGGTCCCCGA GGAGGAGGGG ACTGGGGTCC CGGATTCTTG GGTCTCCAAG AAGTCTGTCC ACAGACTTCT GCCCTGGCTC TTCCCCATCT AGGCCTGGGC AGGAACATAT ATTATTTATT

TAAGCAATTA CTTTTCATGT TGGGGTGGGG ACGGAGGGGA AAGGGAAGCC TGGGTTTTTG TACAAAAATG TGAGAAACCT TTGTGAGACA GAGAACAGGG AATTAAATGT GTCATACATA TCCACTTGAG GGCGATTTGT CTGAGAGCTG GGGCTGGATG CTTGGGTAAC TGGGGCAGGG CAGGTGGAGG GGAGACCTCC ATTCAGGTGG AGGTCCCGAG TGGGCGGGGC AGCGACTGGG AGATGGGTCG GTCACCCAGA CAGCTCTGTG GAGGGAGGGT CTGAGCCTTG CCTGGGGCCG CGCACTGCAT AGGGCCGTTT GTTTGTTTTT TGAGATGGAG TCTCGCTCTG TTGCCTAGGC TGGAGTGCAG TGAGGCAATC TAAGGTCACT GCAACCTCCA CCTCCCGGGT TCAAGCAATT CTCCTGCCTC AGCCTCCCGA TTAGCTGGGA TCACAGGTGT GCACCACCAT GCCCAGCTAA TTATTTATTT CTTTTGTATT TTTAGTAGAG ACAGGGTTTC ACCATGTTGG

CCAGGCTGGT TTCGAACTCC TGACCTCAGG TGATCCTCCT GCCTCGGCCT CCCAAAGTGC TGGGATTACA GGTGTGAGCC ACCACACCTG ACCCATAGGT CTTCAATAAA TATTTAATGG AAGGTTCCAC AAGTCACCCT GTGATCAACA GTACCCGTAT GGGACAAAGC TGCAAGGTCA AGATGGTTCA TTATGGCTGT GTTCACCATA GCAAACTGGA AACAATCTAG ATATCCAACA GTGAGGGTTA AGCAACATGG TGCATCTGTG GATAGAACGC CACCCAGCCG CCCGGAGCAG GGACTGTCAT TCAGGGAGGC TAAGGAGAGA GGCTTGCTTG GGATATAGAA AGATATCCTG ACATTGGCCA GGCATGGTGG CTCACGCCTG TAATCCTGGC ACTTTGGGAG GACGAAGCGA GTGGATCACT GAAGTCCAAG AGTTTGAGAC CGGCCTGCGA GACATGGCAA AACCCTGTCT CAAAAAAGAA AGAATGATGT CCTGACATGA AACAGCAGGC TACAAAACCA CTGCATGCTG

TGATCCCAAT TTTGTGTTTT TCTTTCTATA TATGGATTAA AACAAAAATC CTAAAGGGAA ATACGCCAAA ATGTTGACAA TGACTGTCTC CAGGTCAAAG GAGAGAGGTG GGATTGTGGG TGACTTTTAA TGTGTATGAT TGTCTGTATT TTACAGAATT TCTGCCATGA CTGTGTATTT TGCATGACAC ATTTTAAAAA TAATAAACAC TATTTTTAGA ATAACAGAAT ATCAGCCTCC TCCTCTCCAA AAATAAGCCC TCAGGAGGGG ACAAAGTTGA CCGCTGATTG AGCCTGTCAG GGCTGTGCAC-3' (FRAG NO J(SEQ ID NO 11892) 5'-GCTCAGGGCA CATGCCTCCC CTCCCCAGGC CGCGGCCCAG CTGACCCTCG GGGCTCCCCC GGCAGCGGAC AGGGAAGGGT TAAAGGCCCC CGGCTCCCTG

CCCCCTGCCC TGGGGAACCC CTGGCCCTGT GGGGACATGA ACTGTGTTTG CCGCCTGGTC CTGGTCGTGC TGAGCCTGTG GCCAGATACA GCTGTCGCCC CTGGGCCACC ACCTGGCCCC CCTCGAGTTT CCCCAGACCC TCGGGCCGAG CTGGACAGCA CCGTGCTCCT GACCCGCTCT CTCCTGGCGG ACACGCGGCA GCTGGCTGCA CAGCTGAGGG ACAAATTCCC AGCTGACGGG GACCACAACC TGGATTCCCT GCCCACCCTG GCCATGAGTG CGGGGGCACT GGGAGCTCTA CAGCTCCCAG GTGTGCTGAC AAGGCTGCGA GCGGACCTAC TGTCCTACCT GCGGCACGTG CAGTGGCTGC GCCGGGCAGG TGGCTCTTCC CTGAAGACCC TGGAGCCCGA GCTGGGCACC CTGCAGGCCC GACTGGACCG GCTGCTGCGC CGGCTGCAGC TCCTGATGTC CCGCCTGGCC CTGCCCCAGC CACCCCCGGA CCCGCCGGCG CCCCCGCTGG CGCCCCCCTC CTCAGCCTGG GGGGGCATCA

GGGCCGCCCA CGCCATCCTG GGGGGGCTGC ACCTGACACT TGACTGGGCC GTGAGGGGAC TGCTGCTGCT GAAGACTCGG CTGTGACCCG GGGCCCAAAG CCACCACCGT CCTTCCAAAG CCAGATCTTA TTTATTTATT TATTTCAGTA CTGGGGGCGA AACAGCCAGG TGATCCCCCC GCCATTATCT CCCCCTAGTT AGAGACAGTC CTTCCGTGAG GCCTGGGGGA CATCTGTGCC TTATTTATAC TTATTTATTT CAGGAGCAGG GGTGGGAGGC AGGTGGACTC CTGGGTCCCC GAGGAGGAGG GGACTGGGGT CCCGGATTCT TGGGTCTCCA AGAAGTCTGT CCACAGACTT CTGCCCTGGC TCTTCCCCAT CTAGGCCTGG GCAGGAACAT ATATTATTTA TTTAAGCAAT TACTTTTCAT GTTGGGGTGG GGACGGAGGG GAAAGGGAAG CCTGGGTTTT TGTACAAAAA TGTGAGAAAC CTTTGTGAGA CAGAGAACAG GGAATTAAAT GTGTCATACA TATCC-3' (FRAG NO J(SEQ DDNO 11890)

5'-CAGCTGCGGC ATCCTCTGTC TCAGAGTCTT GGTGTCTCTG TTCCTTTCCC CTCGGGGTCT CCCTGGGTCT CCCCAAGTCC CTCCTGCTGT CTTCCTCCCG CTCTCTGATC TCTGACTCCC AGAACCTCTC CCTCTGTCTC CAGGGCTGCC CCTCTGATCC TCTTTGCTTC TCTGGTGTGT CTCTCTGGCT GCCTCCATCT CTGTGGATCT CCGTCTCCCT GTCTCTGTCT CAGTCTGTCC TTCACTCTGT GTGTGTGTGT GTCTCTCTCT CTCTCTCTCC TTCCCTTCCA CTCCCTCTTC CTCCTGCCTC CACCTCTCCA GGCCCCTGTC

TTGTCCCTCC GTCCGGCCTT TCTCTGCCTT TCCGTCCTCC TGCCTCCCCA TCTCTCTCTG CTAGTCCTGT CCAGCCGGAC CCCCACCCAC AGTCGGGCCC CAGCGCTTGA GCCTGAGTGT CTGCTCCGGC CCGTGGAGGT GGAGGGAGGG GACGCCAATG ACCTCACCAG CCCCTCTCCG ACCACCCCCC CCTTTCCCTT TTCAACTTTT CCAACTTTTC CTTCCGTGCC CTCCTCCGAG CGCGGCGGCG TGAGCCCTGC AAGGCAGCCG CTCCGTCTGA ATGGAAAAGG CAGGCAGGGA GGGTGAGTCA GGATGTGTCA GGCCGGCCCT CCCCTGCCGC CTGCCCCCCG CCCGCCCGCC CCAGGCCCCC TATATAACCC CCCAGGCGTC CACACTCCCT CACTGCCGCG GGCCCTGCTG CTCAGGGCAC ATGCCTCCCC TCCCCAGCCG CGGGCCCAGC TGACCCTCGG GGCTCCCCCG GCAGCGGACA GGGAAGGGTT AAAGGCCCCC GGCTCCCTGC CCCCTGCCCT GGGGAACCCC

TGGCCCTGTG GGGACATGAA CTGTAAGTTG GTTCATGGGG AGGGTGGAGG GGACAGGGAG GCAGGGAGGA GAGGGACCCA CGGCGGGGGT GGGAGCAGAC CCCGCTGAGT CGCACAGAGA GGGACCCGGA GACAGGCAGC CGGGGAGGAG AGCAGCTTCG GAGACAGGAG GCGGCGGAGG AGATGGGCAG AGAGAGACAC AGACAGGAGC GGATGGAGGC AGCCAATCAG AGGCGCCGCA GGAGGGACGG GCCAGACAGG GCCCGAGAGG AGCGAGACGC GAGACCGAGC AGGGGCAGGG ACGCAGGGAC TGGTGCCGGG AGGGAGGTGA CCCCCATCGA CCCAGGCCCC AGGGAGCCCG CGGGGACCGG GAGACTCCCT GGGATTCCGG CAGAGAGGCT CCGGAGGGAA ACTGAGGCAG GGTCCGCGGA GAGCGGAGCA AGCCAGGGAG TAGCGACCCC AGCCGGGGGG AGGAGAGAGA CTGGGCGCCG GGGGAAAGCG

GGGAGAGCCG GGCAGATGCG GCCGACGGAG GCGCGGACAG ACCGACGGCT GGCGGGCCCG GGGGGCGGGC TGGGGGTGTG CGAGGCGCGG GCGGCCGGGG AGCGCTGATT GGCTGGCGGG TGGCCGGGTG GGCGGGGCGG CCGGGGTGGG CTGCGGGGAG CGAGCTCCGG ACCCCCGCGC CCCCGGCGCC CCCCGCGCCC CCCGCCGCCA GCTCTCCCGC TCCCGGCGCC CGGCCGGGCC ATGGCTCTGC CCCTCTCCGC CCAGGTGCGC TGCGGCCCGG GCTTCTGCCG CCCACCCGGC GGGCTCCTGG GAGGGCGTCT AAGGGGTCTC CCGTGGGAGA GGTCCGTGTC TCCCGGACTC CGTCCTGGGC TTTTGGCTCC TTCCCCTGCT CCCAGCCAGC TCGGGCTCCC GCGGCCCGGG GAGGGGGCAG GTTCTGGCCT GTGCCTCCCC CACCATCCGC GCCCCGGGGC CCAGATTCCG GCGTCCGGGG GCGGACGGGA GACGCCCGGG CCGCGTCTGC

TCCGACGGGC GGGGCAGCCA GAGCCAGGGA GGGAGAGGGA AGCCCGCCTG GCCCTGCGAC CTGCCCGCGG GCGTTCCACC CTGGGACTTA AGACCTCCAG CTCCATCCTC CCTAAGGCCG GGAGTCCAGG CCCCAGACCC TCCTCCCCGA GACCCAGGAG TCCAGACCCC AGGCCTTCCT CCCTCAGACC TAGGAGTCCA GGCCCCCAGC CTCTCCTCCC TCAGACCCAG GAGGAGTCCA GACCCCAGTT CCTCCTCCCT CAGACCCGGG AGTCCAGCCC AGGCCCTCCT CTCTCAGACC CGGAGTCCAG CCTGAGCTCT CTGCCTTATC CTGCCCCCAG GTGTTTGGCG CCTGGTCCTG GTCGTGCTGA GCCTGTGGCC AGATACAGCT GTCGCCCCTG GGCCACCACC TGGCCCCCCT CGAGTTTCCC CAGACCCTCG GGCCGAGCTG GACAGCACCG TGCTCCTGAC CCGCTCTCTC CTGGCGGACA CGCGGCAGCT GGCTGCACAG CTGGTAGGAG AGACTGGGCT

GGGGCCAGCA CAGGAGTGAG AGGCAGAGAG GAACGGAGAG GAGTCTGCGG GCAGCCACTT GGAGGGGTTC TGGGCTCTCA GGTGGCAGAG TGAGGGAGGG GAAGAGTTGG GGGCCTGGCG TGGGGGATGG AGGGAGCCCC GAGGCTGGGC AGGGGCCACC TCACAGCTTT TTTCCCTGCC AGAGGGACAA ATTCCCAGCT GACGGGGACC ACAACCTGGA TTCCCTGCCC ACCCTGGCCA TGAGTGCAGG GGCACTGGGA GCTCTACAGG TAAGGGCAAG GGAGTGGGCT GGGGACAAGG TGGGAGGCAG GCAGTGAAGG GGGCGGGGAG GATGAGGGGC ACTGGTCGGG TGTTCTCTGA TGTCCCGGCT CTATCCCCAG CTCCCAGGTG TGCTGACAAG GCTGCGAGCG GACCTACTGT CCTACCTGCG GCACGTGCAG TGGCTGCGCC GGGCAGGTGG CTCTTCCCTG AAGACCCTGG AGCCCGAGCT GGGCACCCTG CAGGCCCGAC

TGGACCGGCT GCTGCGCCGG CTGCAGCTCC TGGTATGTCC TGGCCCCAAG ACCTGACACC CCAGACCCCC ACCCCTGGCC CCAAAATCCT GTGGCCTGAG TCCTTGAAGC CTGAGACCCC AGACCCGAGT GCAACAGCCC CGCTCTGAGA CCCTGACACC CTAACAGCCC GCTCTGAGAC CCTGACACCG TAACAGCCCC GCTCTGAGAC CCTGACCCTA ACAGTCCTGC TCTGAGACCC TGACCCTGCA GTCCCAAGAT CCTGTGGCCC TGAGACCCTG AGGCCCTAGA CCCCCAAATC CTGCCCAGAA ACTTCAAATT CTCACCCAAG ACCCTGAGAC TCCATCATCC ATGACCTCAA AGTCCCCAGA TCCCAGCCCC TAAGACCCAA GACCCCATCC TGAAGCCCAA AGCCTTGAGA ATTCAAATCC TCACCTCAAG ACTTGGAGAC CCTGGCCCCA TGACATTGAA AACCATGGAC CTGGCCAGGC GTGGTGGCTC ACGCCTGTAA TCCCAGCACT TTGGGAGGCC GAGGCAAGTG GATCACCTGA

GGTCGGGAGT TCAAGACCAG CCAGACCAAC ATGGTGAAAC CCTGTCTCTA CTAAAAATAC AAAATTAGCC AGGCGTGGTG GTGCATGCCT GTAATCCCAG CTACTTGGGA GGCTGAGGCA GGAGAATCGC TTGAACCTGG GAGGCGGAGG TTGCAGTGAG CCGAGATCGC ACCATTACAC TCCAGCCTGG GCAACAAGAG CAAAACTCCC TCTCTCTCAA AAAAAAAAAA AAAAAAAAAA AAGAAGGAAA AGAAAACCAT GGACCTCCAG ACCCTGAGAC CCCAGGCCCC AGCCCTGAGA TCCTGACATC TTAAAGATCC CAGGCCCTAA GATACAAGAC CTTGACCCAA AGCCAGCCTT GGGACCCTGG CTGTACAAAC CCAAGACCTC CAGGACCTAG ACCCCGAGCC CTGAGGCCCT ATGTCTCACT CCCAACATCG AAAACCCTGA CACCTCAGAT CCTGAGCCTG CGCCTGTACG ACTCCAAGAC CCTCACTTCC AAAGCCAGGC CCAAAGCCCT GAGACCAGAA GACTTCAAAC

CCTGGTTCTT GGGCCTAACT CCAAAGACCC TGGATCTCAA ATTCCAACTT CTAGCTCTGA GACTCCAGCC CTCACCCATG AGTTCCTGAA CTTGAACCCA GAGACCCCAT CTCTAAGACT TCAGCCTTGA GATCCAGGGC CTGACCCTAG ACTCGAGCCC ACAGACCTCA GATACTGTCT GTAAAACCCC AGCTCTGGTG GGGAGCAGTG GCTCACTCCT GTAATCCCAA GGCAGGGGAG GCCAAGGCAG AAGGACCTCT TGAGGCCATG AGTTTGAGAC AGCCTGGGCA GCATAGCAAG ACTCTGTTTC TTAATTATTA TTATTATTAT TATTTTTTGG AGACAGAGTC TCGCGCTCTG TTGCCCAGGC TAGAGTGCAA TGGTGCCATT TCGGCTTGCT GGAACCTCCG CCTCCTGGGC TCAAGCGATT CTCCTGCCTC AGCCTCCTGA GTAGCTGGGA CTTCAGGTGC ACACTGCCAC ACCCGGATAA TTTTTTTGTA TTTTAGTAGA CACAGGGTTT CACCGTGTTG CCCAGGCTGG TCACAAACTC

CTGAGCTCAG GCCATCCGCC CGCCTCGGCC TCCCAAAGCG CTGGGATAAC AGGCGTGACG CCGCGCCTGG CTTCTTAATT GTTCTAACAG CAGCGACAAC AACAAAAACC CAGCTCTGAG ATTCCAGCCC CGGCGACTCT AACAGTCCCA GGCCCGATCC CTCACCTAGA ACCGAGATGC CAGCCCTGAC TCCACAGACT TCACCCCCAA CCCCCACACT CAGCTCTGGA AGCCCGTCCT GACTCCAGCC TCCATTTTCG GAACCCCACA GCCTGAAGAG CTCCCGGCCT AAACACTTCA CCCCACGCGC CACAGTCCCC CTGTGAATAT GCAGCCCCGA TTCAGCTGCA GCTCCACAGC ACCCCTGCCC TGCACCCCCG CTGCACCCCC TACCTGTGAC TCACCTCTCT CCTCTCCCCA CAGATGTCCC GCCTGGCCCT GCCCCAGCCA CCCCCGGACC CGCCGGCGCC CCCGCTGGCG CCCCCCTCCT CAGCCTGGGG GGGCATCAGG GCCGCCCACG CCATCCTGGG GGGGCTGCAG CTGACACTTG

ACTGGGCCGT GAGGGGACTG CTGCTGCTGA AGACTCGGCT GTGACCCGGG GCCCAAAGCC ACCACCGTCC TTCCAAAGCC AGATCTTATT TATTTATTTA TTTCAGTACT GGGGGCGAAA CAGCCAGGTG ATCCCCCCGC CATTATCTCC CCCTAGTTAG AGACAGTCCT TCCGTGAGGC CTGGGGGGCA TCTGTGCCTT ATTTATACTT ATTTATTTCA GGAGCAGGGG TGGGAGGCAG GTGGACTCCT GGGTCCCCGA GGAGGAGGGG ACTGGGGTCC CGGATTCTTG GGTCTCCAAG AAGTCTGTCC ACAGACTTCT GCCCTGGCTC TTCCCCATCT AGGCCTGGGC AGGAACATAT ATTATTTATT TAAGCAATTA CTTTTCATGT TGGGGTGGGG ACGGAGGGGA AAGGGAAGCC TGGGTTTTTG TACAAAAATG TGAGAAACCT TTGTGAGACA GAGAACAGGG AATTAAATGT GTCATACATA TCCACTTGAG GGCGATTTGT CTGAGAGCTG GGGCTGGATG CTTGGGTAAC

TGGGGCAGGG CAGGTGGAGG GGAGACCTCC ATTCAGGTGG AGGTCCCGAG TGGGCGGGGC AGCGACTGGG AGATGGGTCG GTCACCCAGA CAGCTCTGTG GAGGCAGGGT CTGAGCCTTG CCTGGGGCCC CGCACTGCAT AGGGCCGTTT GTTTGTTTTT TGAGATGGAG TCTCGCTCTG TTGCCTAGGC TGGAGTGCAG TGAGGCAATC TAAGGTCACT GCAACCTCCA CCTCCCGGGT TCAAGCAATT CTCCTGCCTC AGCCTCCCGA TTAGCTGGGA TCACAGGTGT GCACCACCAT GCCCAGCTAA TTATTTATTT CTTTTGTATT TTTAGTAGAG ACAGGGTTTC ACCATGTTGG CCAGGCTGGT TTCGAACTCC TGACCTCAGG TGATCCTCCT GCCTCGGCCT CCCAAAGTGC TGGGATTACA GGTGTGAGCC ACCACACCTG ACCCATAGGT CTTCAATAAA TATTTAATGG AAGGTTCCAC AAGTCACCCT GTGATCAACA GTACCCGTAT GGGACAAAGC TGCAAGGTCA

AGATGGTTCA TTATGGCTGT GTTCACCATA GCAAACTGGA AACAATCTAG ATATCCAACA GTGAGGGTTA AGCAACATGG TGCATCTGTG GATAGAACGC CACCCAGCCG CCCGGAGCAG GGACTGTCAT TCAGGGAGGC TAAGGAGAGA GGCTTGCTTG GGATATAGAA AGATATCCTG ACATTGGCCA GGCATGGTGG CTCACGCCTG TAATCCTGGC ACTTTGGGAG GACGAAGCGA GTGGATCACT GAAGTCCAAG AGTTTGAGAC CGGCCTGCGA GACATGGCAA AACCCTGTCT CAAAAAAGAA AGAATGATGT CCTGACATGA AACAGCAGGC TACAAAACCA CTGCATGCTG TGATCCCAAT TTTGTGTTTT TCTTTCTATA TATGGATTAA AACAAAAATC CTAAAGGGAA ATACGCCAAA ATGTTGACAA TGACTGTCTC CAGGTCAAAG GAGAGAGGTG GGATTGTGGG TGACTTTTAA TGTGTATGAT TGTCTGTATT TTACAGAATT TCTGCCATGA CTGTGTATTT

TGCATGACAC ATTTTAAAAA TAATAAACAC TATTTTTAGA ATAACAGAAT ATCAGCCTCC TCCTCTCCAA AAATAAGCCC TCAGGAGGGG ACAAAGTTGA CCGCTGATTG AGCCTGTCAG GGCTGTGCAC-3' (FRAG NO _)(SEQ ID NO 11891)

Human GM-CSF Nucleic Acid and Antisense Oligonucleotide Fragments

5'-CTTGBGCBGG BBGCTCTGGG GCBGGGBGCT GGCBGGGCCC BGGGGGGTGG CTTCCTGCBC TGTCCBGBGT GCBCTGTGCC BCBGCBGCBG CTGCBGGGCC BTCBGCTTCB TGGGGCTCTG GGTGGCBGGT CCBGCCBTGG GTCTGGGTGG GGCTGGGCTG CBGGCTCCGG GCGGTCCBGCCBTGGGTCTG GGGGCTGGG CTGCBGGCTC

CGGGCGGGCG GGTGCGGGCT GCGTGCTGGG GGCTGCCCCG CAGGCCCTGC GGTCCBGCCB TGGGTCTGGG GGCTGGGCTG CBGGCTCCGG GCGGGCGGGT

GCGGGCTGCG TGCTGGGGGC TGCCCCGCAG GCCCTGC-3' (FRAG NO 1847) (SEQ ED NO 11229)

5'-GBGCBGG BBG-3' (FRAG NO 1848) (SEQ IDNO 11230)

5'-GCCBCBGCBGCBGC-3' (FRAG NO 1849) (SEQ DD NO 11231) 5'-GGG TGC GGG C-3' (FRAG NO 1850) (SEQ DDNO 11232)

5'-GGT CCB GCC BTG GGT CTG GG-3' (FRAG NO 1300)(SEQ DD NO 10678)

5'-GGC TGG GCT GCB GGC TCC GG-3' (FRAG NO 1301)(SEQ ID NO 10679)

5'-GCG GGC GGG TGC GGG CTG CGT GCT GGG-3' (FRAG NO 1302)(SEQ ID NO 10680)

5'-GGC TGC CCC GCA GGC CCT GC-3' (FRAG NO 1303)(SEQ ID O 10681) 5'-CTTGBGCBGG BBGCTCTGGG GCBGGGBGCT GGCBGGGCCC BGGGGGGTGG CTTCCTGCBC TGTCCBGBGT GCBCTGTGCC BCBGCBGCBG CTGCBGGGCC

BTCBGCTTCB TGGGGCTCTG GGTGGCBGGT CCBGCCBTGG GTCTGGGTGG GGCTGGGCTG CBGGCTCCGG GC-3' (FRAG NO 1851) (SEQ ID NO 11233)

Human Tumor Necrosis Factor C Antisense Oligonucleotide Fragments

5-GCBCCGCCTG GBGCCCTGGG GCCCCCCTGT CTTCTTGGGG BGCGCCTCCT CGGCCBGCTC CBCGTCCCGG BTCBTGCTTT CBGTGCTCBT GGTGTCCTTT CCBGGGGBGB GBGGGGCTGG TCCTCTGCTG TCCTTGCTGG TGCTCBTGGT GTCCTTTCCG CCCTGGGGCC CCCCTGTCTT CTTGGGGCCT CTTCCCTCTG GGGGCCGTCT CTCTCCCTCT CTTGCGTCTC TCTCTTTCTC TCTCTCTCTT CCCCTTTCCC GCTCTTTCTG TCTCGGTGTC TGGTTTTCTC TCTCCGCTGG CTGCCTGTCT GGCCTGCGCT CTTGGCCTGT

GCTGTTCCTC CTCCGGTTCC TGTCCTCTCT GTCTGTCGCC CCCTCTGGGG TCTCCCTCTG GGTGGTGGTC TTGTTGCTTG GGCTGGGCTC CGTGTCTCCB GTGCTCBTGG TGTCCGCTGB GGGBGCGTCT GCTGGCGCTG GTCCTCTGCTGTC CTTGCTGGTG CTCBTGGTGT CCTTTCCGCC CTGGGGCCCC CCTGTCTTCT TGGGGCCTCT TCCCTCTGGG GGCCGTCTC TCTCCCTCTC TTGCGTCTCT CTCTTTCTCT CTCTCTCTTC CCCTTTCCCG CTCTTTCTGT CTCGGTGTCT GGTTTTCTCT CTCCGCTGGC TGCCTGTCTG GCCTGCGCTC TTGGCCTGTG CTGTTCCTCC TCCGGTTCCT GTCCTCTCTG TCTGTCGCCC CCTCTGGGGT CTCCCTCTGG CGTGGTGGTC TTGTTGCTTG GGCTGGGCTC CGTGTCTCCB GTGCTCBTGG TGTCCGCTGB GGGBGCGTCT GCTGGC-3' (FRAG NO 1852)(SEQ DD NO 11234)

5'-GGGGCCCCCC-3' (FRAG NO 1853) (SEQ ID NO 11235) 5'- GGG GGC CG TCT-3' (FRAG NO 1854) (SEQ ED NO 11236) 5'-CCBGGGGBGB GBGGGGCTGG-3' (FRAG NO 1855) (SEQ ED NO 11237) 5'-GCBCCGCCTG GBGCCCTGGG GCCCCCCTGT CTTCTTGGGG BGCGCCTCCT CGGCCBGCTC CBCGTCCCGG BTCBTGCTTT CBGTGCTCBT GGTGTCCTTT CCBGGGGBGB GBGGG-3' (FRAG NO 1304) (SEQ DD O 10682)

5'-GCT GGT CCT CTG CTG TCC TTG CTG GTG CTC BTG GTG TCC TTT CC GCC CTG GGG CCC CCC TGT CTT CTT GGG G CCT CTT CCC TCT GGG GGC CG TCT CTC TCC CTC TCT TGC GTC TCT C TCT TTC TCT CTC TCT CTT CCC C TTT CCC GCT CTT TCT GTC TC GGT GTC TGG TTT TCT CTC TCC GCT GGC TGC CTG TCT GGC CTG CGC TCT T GGC CTG TGC TGT TCC TCC TCC GGT TCC TGT CCT CTC TGT CTG TC GCC CCC TCT GGG GTC TCC CTC TGG C GTG GTG GTC TTG TTG CTT GGG CTG GGC TCC GTG TCT C CBG TGC TCB TGG TGT CC-3' (FRAG NO 1305) (SEQ DD NO 10683) 5'-GCT GBG GGB GCG TCT GCT GGC GCT GGT CCT CTG CTG TCC TTG CTG GTG CTC BTG GTG TCC TTT CC GCC CTG GGG CCC CCC TGT CTT CTT GGG G CCT CTT

CCC TCT GGG GGC CG TCT CTC TCC CTC TCT TGC GTC TCT C TCT TTC TCT CTC TCT CTT CCC C TTT CCC GCT CTT TCT GTC TC GGT GTC TGG TTT TCT CTC TCC

GCT GGC TGC CTG TCT GGC CTG CGC TCT T GGC CTG TGC TGT TCC TCC TCC GGT TCC TGT CCT CTC TGT CTG TC GCC CCC TCT GGG GTC TCC CTC TGG C GTG GTG

GTC TTG TTG CTT GGG CTG GGC TCC GTG TCT C CBG TGC TCB TGG TGT CC GCT GBG GGB GCG TCT GCT GGC-3'(FRAG NO 1306)(SEQ DD NO 10684) 5'-GCT GGT CCT CTG CTG TCC TTG CTG 3' (FRAG NO 1655) (SEQ DD NO 11033)

5'-GTG CTC BTG GTGTCC TTT CC-3' (FRAG NO 1656)(SEQ DD NO 11034)

5'-GCC CTG GGG CCC CCC TGT CTT CTT GGG G-3' (FRAG NO 1657)(SEQ DDNO 11035)

5'-CCT CTT CCC TCT GGG GGC CG-3' (FRAG NO 1658)(SEQ DD NO 11036)

5'-TCT CTC TCC CTC TCT TGC GTC TCT C-3' (FRAG NO 1659)(SEQ EDNO 11037) 5'-TCT TTC TCT CTC TCT CTT CCC C-3' (FRAG NO 1660)(SEQ DD NO 11038)

5'-TTT CCC GCT CTT TCT GTC TC-3' (FRAG NO 1661)(SEQ ED NO 11039)

5'-GGT GTC TGG TTT TCT CTC TCC-3' (FRAG NO 1662)(SEQ DD NO 11040)

5'-GCT GGC TGC CTG TCT GGC CTG CGC TCT T-3' (FRAG NO 1663)(SEQ DDNO 11041)

5'-GGC CTG TGC TGT TCC TCC-3' (FRAG NO 1664)(SEQ ID NO 11042) 5'-TCC GGT TCC TGT CCT CTC TGT CTGTC-3' (FRAG NO 1665)(SEQ DD NO 11043)

5'-GCC CCC TCT GGG GTC TCC CTC TGG C-3' (FRAG NO 1666)(SEQ DD NO 11044)

5'-GTG GTG GTC TTG TTG CTT-3' (FRAG NO 1667)(SEQ DD NO 11045)

5'-GGG CTG GGC TCC GTG TCT C-3' (FRAG NO 1668)(SEQ ID NO 11046)

5'-CBG TGC TCB TGG TGT CC-3' (FRAG NO 1669)(SEQ ID NO 11047) 5'-GCT GBG GGB GCG TCT GCT GGC-3' (FRAG NO 1670)(SEQ ID NO 11048)

Human Leukotriene C4 Synthase Nucleic Acids and Antisense Oligonucleotide Fragments

5'-CTCGGTBGBC GCGCTCGBBC TCGGGTGGGC CGGTGGTGBG CGGCGGCGBCB CGCGGBBGGC CCTGCGCGCC GBGBTCBCCTG CBGGGBGBBG TBGGCTTGCB

GCBGGBCTCC CBGGBGGGTG BCBGCBGCCB GTBGBGCTBC CTCGTCCTTC BTGGTBCCGT CGGTGTGGTG GCBCGGGCTG TGTGTGBBGG CGBGCTGGGC CCCGTCTGCT

GCTCCTCGTG CCGCCTGGTC CTTCA TGG TA CCGTCGGTGT GGTGGCCTCG GGTGGGCCGG TGGTGGGGCG CGCGCGCTCG CGTGGCTCCG GCTCTTCTTT CCCGGCTCCGT CGGCCCGGGG GCCTTGGTCT CCCTCGTCCT TCBTGGTBCC G-3' (FRAG NO 1856) (SEQ ID NO 11238)

5'-GCB GCBGGBC-3' (FRAG NO 1857) (SEQ ID NO 11239)

5'-CCCGGCTCCG-3' (FRAG NO 1858) (SEQ DD NO 11240)

5'-CGGCCCGGGG GCC-3' (FRAG NO 1859) (SEQ ID NO 11241)

5'-CB CGCGG-3' (FRAG NO 1860) (SEQ ID NO 11242) 5'-GCC CCG TCT GCT GCT CCT CGT GCC G-3' (FRAG NO 1307)(SEQ DDNO 10685)

5'-CCT CGT CCT TCA TGG TAC CGT CGG TGT GGT GGC-3' (FRAG NO 1308)(SEQ ID NO 10686)

5'-CTC GGG TGG GCC GGT GGT G-3' (FRAG NO 1309)(SEQ ID NO 10687)

5'-GGG CGC GCG CGC TCG CGT-3' (FRAG NO I3I0)(SEQ ID NO 10688)

5'-GGC TCC GGC TCT TCT TTC CCG GCT CCG TCG GCC CGG GGG CCT TGG TCT C-3'(FRAGNO 1311)(SEQ ED NO 10689) 5'-CCT CGT CCT TCB TGG TBC CG-3' (FRAG NO 1312)(SEQ ID NO 10690)

5'-CTCGGTBGBC GCGCTCGBBC TCGGGTGGGC CGGTGGTGBG CGGCGGCGBCB CGCGGBBGGC CCTGCGCGCC GBGBTCBCCTG CBGGGBGBBG TBGGCTTGCB

GCBGGBCTCC CBGGBGGGTG BCBGCBGCCB GTBGBGCTBC CTCGTCCTTC BTGGTBCCGT CGGTGTGGTG GCBCGGGCTG TGTGTGBBGG CGBGCTGG-3' (FRAGNO 1861)

(SEQ ED NO 11243)

Human Endothelin-1 Nucleic Acids and Antisense Oligonucleotide Fragments 5'-BCCGGCGGBG CCGCCBGGGT GGBCTGGGBG TGGGTTTCTC CCCGCCGTTC TCBCCCBCCG CGCTGBGCTC BGCGCCTBBG BCTGCTGTTT CTGGBGCTCC TTGGCBBGCC

BCBBBCBGCB GBGBGBBBBT CBTGBGCBBB TBBTCCBTTC TGBBBBBBBG GGBTCBBBBB CCTCCCGTTC CCCGTTCGCC TGGCGCGCGC TGCGGGTTCC TCGTGGGTTT

CTCCCCGCCG TTCTCCGGTC TGTTGCCTTT GTGGGCTTCT TGTCTTTTTG GCTGTTCTTT TCCTGCTTGG CGTCTTTTCC TTTCTTTGTG CTCGGTTGTG GGTCCGCTGG

TCCTTTGCCC TGTGTGTTTC TGCTGCCCGT TCGCCTGGCG CGCGCTGCGG GTTCCTCGTG GGTTTCTCCC CGCCGTTCTC CGGTCTGTTG CCTTTGTGGG CTTCTTGTCT

TTTTGGCTGT TCTTTTCCTG CTTGGCGTCT TTTCCTTTCT TTGTGCTCGG TTGTGGGTCC GCTGGTCCTT TGCCCTGTGT GTTTCTGCTG-3' (FRAG NO 1862) (SEQ ID NO 11244)

5'-CCGGCGGBG CCGCCBGGGT GGBC-3' (FRAG NO 1863) (SEQ ID NO 11245)

5'-CCGCCBGGG-3' (FRAG NO 1864) (SEQ DD NO 11246)

5'-GGCGCGCGC-3' (FRAG NO 1865) (SEQ DD NO 11247)

5'-GTGGGTCCGC-3' (FRAG NO 1866) (SEQ ID NO 11248) 5'-CCCGTTCGCCTGGCGC-3' (FRAG NO 1313)(SEQ D NO 10691)

5'-GCGCTGCGGGTTCCTC-3' (FRAG NO 1314)(SEQ ID NO 10692)

5'-GTGGGTTTCTCCCCGCCGTTCTC-3' (FRAG NO 1315)(SEQ DDNO 10693)

5'-CGGTCTGTTGCCTTTGTGGG -3' (FRAG NO 1316)(SEQ ID NO 10694)

5'-CTTCTTGTCTTTTTGGCT-3' (FRAG NO 1317)(SEQ ID NO 10695) 5'-GTTCTTTTCCTGCTTGGC-3' (FRAG NO 1318)(SEQ ID NO 10696)

5'-GTCTTTTCCTTTCTT-3' (FRAG NO 1319)(SEQ DD NO 10697)

5'-TGTGCTCGGTTGTGGGTC-3' (FRAG NO 1320)(SEQ ID NO 10698)

5'-CGCTGGTCCTTTGCC-3' (FRAG NO 1321)(SEQ ID O 10699)

5'-CTGTGTGTTTCTGCTG-3' (FRAG NO 1322){SEQ ID NO 10700) 5'-CCCGTTCGCCTGGCGC-3' (FRAG NO 1323)(SEQ DD O 10701)

5'-GCGCTGCGGGTTCCTC-3' (FRAG NO 1324)(SEQ ID NO 10702)

5'-GTGGGTTTCTCCCCGCCGTTCTC-3' (FRAG NO 1325(SEQ ID NO 10703)

5'-CGGTCTGTTGCCTTTGTGGG-3' (FRAG NO 1326)(SEQ DD NO 10704)

5'-CTTCTTGTCTTTTTGGCT-3' (FRAG NO 1327)(SEQ ID NO 10705) 5'-GTTCTTTTCCTGCTTGGC-3' (FRAG NO 1328)(SEQ ID NO 10706)

5'-GTCTTTTCCTTTCTT-3' (FRAG NO 1329){SEQ ID NO 10707)

5'-TGTGCTCGGTTGTGGGTC-3' (FRAG NO 1330)(SEQ ID NO 10708)

5'-CGCTGGTCCTTTGCC-3' (FRAG NO 1331)(SEQ ID NO 10709)

5'-CTGTGTGTTTCTGCTG-3' (FRAG NO 1332)(SEQ ID NO 10710) Endothelin Receptor ET-B Nucleic Acids and Antisense Oligonucleotide Fragments

5'-GCCCTGTCGG GCGGGAAGCC TCTCTCCTCT CCCCAGATC CGCGACAGGC CGCAGGCAAG AACCAGCGCA ACCAGGGCGC GTCCGCACAG ACTTGGAGGC

GGCTGCATGC TGCTACCTGC TCCAGAAGCG TCCGGTGGCC GCCGCGCC CTGTCGGGCG GGBBGCCTCT CTCCTCTCCC CBGBTCCGCG BCBGGCCGCB GGCBBGBBCC

BGCGCBBCCB GGGCGCGTCC GCBCBGBCTT GGBGGCGGCT GCBTGCTGCT BCCTGCTCGGGCG GGBBGCCTCCG GTGGCCGCCG CGCGTCCGGT GGCCGCCGCG

CCTCTCTCCT CTCCCCGTGG CCCTGTCGGG CGGGTCCTGC CGTCCTGTCT CCTTTTCTTT TGCTGTCTTG TCTTCCCGTC TCTGCTTT-3' (FRAG NO 1867) (SEQ ID NO 11249) 5'-CGGGCG GGBBGCC-3' (FRAG NO 1868) (SEQ ID NO 11250)

5'-CGGGCGGG-3' (FRAG NO 1869) (SEQ DD NO 11251) (FRAG NO 1870) (SEQ ID NO 11252)

5'-GCGTCCGGTGGCCGCCGC-3' (FRAG NO 1333)(SEQ ID NO I07I 1)

5'-GCCTCTCTCCTCTCCCC-3' (FRAG NO 1334)(SEQ ID NO 10712) 5'-GTGGCCCTGTCGGGCGGG-3' (FRAG NO 1335)(SEQ DD NO 10713)

5'-TCCTGCCGTCCTGTCTCCTTT-3' (FRAG NO 1336)(SEQ DD NO 10714)

5'-TCTTTTGCTGTCTTGT-3' (FRAG NO 1337)(SEQ DD NO 10715)

5'-CTTCCCGTCTCTGCTTT-3' (FRAG NO 1338)(SEQ ID NO 10716)

5'-GCCCTGTCGG GCGGGAAGCC TCTCTCCTCT CCCCAGATC CGCGACAGGC CGCAGGCAAG AACCAGCGCA ACCAGGGCGC GTCCGCACAG ACTTGGAGGC GGCTGCATGC TGCTACCTGC TCCAGAAGCG TCCGGTGGCC GCCGC-3' (FRAG NO 1871) (SEQ DD NO 11253)

5'-GCCCTGTCGG GCGGGBBGCC TCTCTCCTCT CCCCBGBTCC GCGBCBGGCC GCBGGCBBGB BCCBGCGCB BCCBGGGCGC GTCCGCBCBG BCTTGGBGGC GGCTGCBTGC

TGCTBCCTGC TCCBGBBGCG TCCGGTGGCC GCCGC-3' (FRAG NO 1872) (SEQ ID NO 11254)

Endothelin ETA Receptor Nucleic Acids and Antisense Oligonucleotide Fragments

5'-GTCTGTCCTC CCCGTCTCCT CCCACTGCTT CTCCCGGGGG CTTCCCCGGC TTCGGGTGGC CGGTGTCCCG GGCTCCGGCG CGGCGGCGGC TTCGGCTGCG GGTGGGTGGC GCGGGCTGCC GGGTCCGCGC GGCGCCTGGG CCCTTGTGCT GCTTTTTGCT TGTTCCGTTC TGGCTGCTCC GGTCTGTGTT GTGGTTGTTT TGTTTCTTCT

TGGGTGTGGG CCTTGCGGTT TTGGCTGTGG GCCCTTTGGG GCCTTGGCTT CTGGCTCGTC TGTCCTCCCC GTCTCCTCCC ACTGCTTCT CCCGGGGGCT TCCCCGGCTT CGGGTGGCCG GTGTCCCGGG CTCCGGCGCG GCGGCGGCTT CGGCTGCGGG TGGGTGGCGC GGGCTGCCGG GTCCGCGCGG CGCCTGGGCC CTTGTGCTGC TTTTTGCTTG TTCCGTTCTG GCTGCTCCGG TCTGTGTTGT GGTTGTTTTG TTTCTTCTTG GGTGTGGGCC TTGCGGTTTT GGCTGTGGGC CCTTTGGGGC CTTGGCTTCT GGCTCCAT CCACATGATT GCTTAGATTT GTGCTGTATC TCTCAGGATT ATCACTGATT ACACATCCAA CCAGTGCCAG CCAAAAGGAT GCCCTGAGGC AAAGGGTTTC CATCTTGAGG CAAATTTGAG GACBTCCBC BTGBTTGCTT BGBTTTGTGC TGTBTCTCTC BGGBTTBTCB CTGBTTBCBC BTCCBBCCBG TGCCBGCCBB BBGGBTGCCC TGBGGCBBBG

GGTTTCCBTC TTGBGGCBBB TTTGBGGB-3' (FRAG NO 1873) (SEQ ID NO 11255) 5'-GBGGCBBBGGG-3' (FRAG NO 1874) (SEQ DD NO 11256) 5'-GCCBGCCBB BBGGB-3' (FRAG NO 1875) (SEQ ID NO 11257) 5'-CGCCTGGGCC C-3' (FRAG NO 1876) (SEQ ID NO 11258)

5'-GTCTGTCCTCCCCGTCTCCTCCC-3' (FRAG NO 1339)(SEQ ID N0 10717)

5'-ACTGCTTCTCCCGGGG 3' (FRAG NO 1340)(SEQ DD NO 10718)

5'-GCTTCCCCGGCTTC-3' (FRAG NO 1341)(SEQ ID NO 10719) 5'-GGGTGGCCGGTGTCCCGGGCTCCGGCGCGGCGGC-3' (FRAG NO 1342)(SEQ ED NO 10720)

5'-GGCTTCGGCTGC-3' (FRAG NO 1343)(SEQ ID NO 10721)

5'-GGGTGGGTGGCGCGG-3' (FRAG NO 1344)(SEQ ID NO 10722)

5'-GCTGCCGGGTCCGCGCGGCGCCTGGGCC-3' (FRAG NO 1345)(SEQ DD NO 10723)

5'-CTTGTGCTGCTTTT-3' (FRAG NO 1346(SEQ ID NO 10724) 5'-TGCTTGTTCCGTTC-3' (FRAG NO 1347)(SEQ DD NO 10725)

5'-TGGCTGCTCCGGTCTGTGTTGTGGTTGTTTTG-3' (FRAG NO 1348)(SEQ ID NO 10726)

5'-TTTCTTCTTGGGTGTGGG-3' (FRAG NO 1349)(SEQ ID NO 10727)

5'-CCTTGCGGTTTTGG-3' (FRAG NO 1350)(SEQ ID NO 10728)

5'-CTGTGGGCCCTTTG-3' (FRAG NO 1351)(SEQ DD NO 10729) 5'-GGGCCTTGGCTTCTGGCTC-3' (FRAG NO 1352)(SEQ DD NO 10730)

5'-CATCCACATG ATTGCTTAGA TTTGTGCTGT ATCTCTCAGG ATTATCACTG ATTACACATC CAACCAGTGC CAGCCAAAAG GATGCCCTGA GGCAAAGGGT TTCCATCTTG

AGGCAAATTT GAGGA-3' (FRAGNO 1353) (SEQ DD O 10731)

5'-CBTCCBCBTG BTTGCTTBGB TTTGTGCTGT BTCTCTCBGG BTTBTCBCTG BTTBCBCBTC CBBCCBGTGC CBGCCBBBBG GBTGCCCTGB GGCBBBGGGT TTCCBTCTTG

BGGCBBBTTT GBGGB-3' (FRAG NO 1354)(SEQ ID NO 10732) Endothelin Receptor A Nucleic Acid and Antisense Oligonucleotide Fragments

5'-GCCACCATGG AAACCCTTTG CCTCAGGGCA TCCTTTTGGC TGGCACTGGT TGGATGTGTA ATCAGTGATA ATCCTGAGAG ATACAGCACA AATCTAAGCA ATCATGTGGA TGATTTCACC ACTTTTCGTG GCACAGAGCT CAGCTTCCTG GTTACCACTC ATCAACCCAC TAATTTGGTC CTACCCAGCA ATGGCTCAAT GCACAACTAT TGCCCACAGC AGACTAAAAT TACTTCAGCT TTCAAATACA TTAACACTGT GATATCTTGT ACTATTTTCA TCGTGGGAAT GGTGGGGAAT GCAACTCTGC TCAGGATCAT TTACCAGAAC AAATGTATGA GGAATGGCCC CAACGCGCTG ATAGCCAGTC TTGCCCTTGG AGACCTTATC TATGTGGTCA TTGATCTCCC TATCAATGTA TGGCTGGGCG CTGGCCTTTT GATCACAATG ACTTTGGCGT ATTTCTTTGC AAGCTGTTCC CCTTTTTGCA GAAGTCCTCG GTGGGGATCA CCGTCCTCAA CCTCTGCGCT CTTAGTGTTG

ACAGGTACAG AGCAGTTGCC TCCTGGAGTC GTGTTCAGGG AATTGGGATT CCTTTGGTAA CTGCCATTGA AATTGCCTCC ATCTGGATCC TGTCCTTTAT CCTGGCCATT CCTGAAGCGA TTGGCTTCGT CATGGTACCC TTTGAATATA GGGGTGGACA GCATAAAACC TGTATGCTCA ATGCCACATC AAAATTCATG GAGTTCTACC AAGATGTAAA GGACTGGTGG CTCTTCGGGT TCTATTTCTG TATGCCCTTG GTGTGCACTG CGATCTTCTA CACCCTCATG ACTGGTGAGA TGTTGAACAG AAGGAATGGC AGCTTGAGAA TTGCCCTCAG TGAACATCTT AAGCAGCGTC GAGAAGTGGC AAAAACAGTT TTCTGCTTGG TTGTAATTTT TGCTCTTTGC TGGTTCCCTC TTCATTTAAG CCGTATATTG AAGAAAACTG TGTATAACGA GATGGACAAG AACCGATGTG AATTACTTAG TTTCTTACTG CTCATGGATT ACATCGGTAT TAACTTGGCA ACCATGAATT CATGTATAAA

CCCCATAGCT CTGTATTTTG TGAGCAAGAA ATTTAAAAAT TGTTTCCAGT CATGCCTCTG CTGCTGCTGT TACCAGTCCA AAAGTCTGAT GACCTCGGTC CCCATGAACG GAACAAGCAT CCAGTGGAAG AACCACGATC AAAACAACCA CAACACAGAC CGGAGCAGCC ATAAGGACAG CATGAACTGA CCACCCTTAG AAGCACTCCT GAATTCGGGA AAAAGTGAAG GTGTAAAAGC AGCACAAGTG CAATAAGAGA TATTTCCTCA AATTTGCCTC AAGATGGAAA CCCTTTGCCT CAGGGCATCC TTTTGGCTGG CACTGGTTGG ATGTGTAATC AGTGATAATC CTGAGAGATA CAGCACAAAT CTAAGCAATC ATGTGGATGA TTTCACCACT TTTCGTGGCA CAGAGCTCAG CTTCCTGGTT ACCACTCATC AACCCACTAA TTTGGTCCTA CCCAGCAATG GCTCAATGCA CAACTATTGC CCACAGCAGA CTAAAATTAC TTCAGCTTTC AAATACATTA ACACTGTGAT

ATCTTGTACT ATTTTCATCG TGGGAATGGT GGGGAATGCA ACTCTGCTCA GGATCATTTA CCAGAACAAA TGTATGAGGA ATGGCCCCAA CGCGCTGATA GCCAGTCTTG CCCTTGGAGA CCTTATCTAT GTGGTCATTG ATCTCCCTAT CAATGTATTT AAGCTGCTGG CTGGGCGCTG GCCTTTTGAT CACAATGACT TTGGCGTATT TCTTTGCAAG CTGTTCCCCT TTTTGCAGAA GTCCTCGGTG GGGATCACCG TCCTCAACCT CTGCGCTCTT AGTGTTGACA GGTACAGAGC AGTTGCCTCC TGGAGTCGTG TTCAGGGAAT TGGGATTCCT TTGGTAACTG CCATTGAAAT TGTCTCCATC TGGATCCTGT CCTTTATCCT GGCCATTCCT GAAGCGATTG GCTTCGTCAT GGTACCCTTT GAATATAGGG GTGAACAGCA TAAAACCTGT ATGCTCAATG CCACATCAAA ATTCATGGAG TTCTACCAAG ATGTAAAGGA CTGGTGGCTC TTCGGGTTCT ATTTCTGTAT GCCCTTGGTG

TGCACTGCGA TCTTCTACAC CCTCATGACT TGTGAGATGT TGAACAGAAG GAATGGCAGC TTGAGAATTG CCCTCAGTGA ACATCTTAAG CAGCGTCGAG AAGTGGCAAA AACAGTTTTC TGCTTGGTTG TAATTTTTGC TCTTTGCTGG TTCCCTCTTC ATTTAAGCCG TATATTGAAG AAAACTGTGT ATAACGAGAT GGACAAGAAC CGATGTGAAT TACTTAGTTT CTTACTGCTC ATGGATTACA TCGGTATTAA CTTGGCAACC ATGAATTCAT GTATAAACCC CATAGCTCTG TATTTTGTGA GCAAGAAATT TAAAAATTGT TTCCAGTCAT GCCTCTGCTG CTGCTGTTAC CAGTCCAAAA GTCTGATGAC CTCGGTCCCC ATGAACGGAA CAAGCATCCA GTGGAAGAAC CACGATCAAA ACAACCACAA CACAGACCGG AGCAGCCATA AGGACAGCAT GAACTGACCA CCCTTAGAAG CACTCCTCGG TACTCCCATA ATCCTCTCGG AGAAAAAAAT CACAAGGCAA CTGTGAGTCC

GGGAATCTCT TCTCTGATCC TTCTTCCTTA ATTCACTCCC ACACCCAAGA AGAAATGCTT TCCAAAACCG CAAGGGTAGA CTGGTTTATC CACCCACAAC ATCTACGAAT CGTACTTCTT TAATTGATCT AATTTACATA TTCTGCGTGT TGTATTCAGC ACTAAAAAAT GGTGGGAGCT GGGGGAGAAT GAAGACTGTT AAATGAAACC AGAAGGATAT TTACTACTTT TGCATGAAAA TAGAGCTTTC AAGTACATGG CTAGCTTTTA TGGCAGTTCT GGTGAATGTT CAATGGGAAC TGGTCACCAT GAAACTTTAG AGATTAACGA CAAGATTTTC TACTTTTTTT AAGTGATTTT TTTGTCCTTC AGCCAAACAC AATATGGGCT CAAGTCACTT TTATTTGAAA TGTCATTTGG TGCCAGTATC CCGAATTC GAATTCGGGA AAAAGTGAAG GTGTAAAAGC AGCACAAGTG CAATAAGAGA TATTTCCTCA AATTTGCCTC AAGATGGAAA CCCTTTGCCT CAGGGCATCC TTTTGGCTGG

CACTGGTTGG ATGTGTAATC AGTGATAATC CTGAGAGATA CAGCACAAAT CTAAGCAATC ATGTGGATGA TTTCACCACT TTTCGTGGCA CAGAGCTCAG CTTCCTGGTT ACCACTCATC AACCCACTAA TTTGGTCCTA CCCAGCAATG GCTCAATGCA CAACTATTGC CCACAGCAGA CTAAAATTAC TTCAGCTTTC AAATACATTA ACACTGTGAT ATCTTGTACT ATTTTCATCG TGGGAATGGT GGGGAATGCA ACTCTGCTCA GGATCATTTA CCAGAACAAA TGTATGAGGA ATGGCCCCAA CGCGCTGATA GCCAGTCTTG CCCTTGGAGA CCTTATCTAT GTGGTCATTG ATCTCCCTAT CAATGTATTT AAGCTGCTGG CTGGGCGCTG GCCTTTTGAT CACAATGACT TTGGCGTATT TCTTTGCAAG CTGTTCCCCT TTTTGCAGAA GTCCTCGGTG GGGATCACCG TCCTCAACCT CTGCGCTCTT AGTGTTGACA GGTACAGAGC AGTTGCCTCC TGGAGTCGTG TTCAGGGAAT

TGGGATTCCT TTGGTAACTG CCATTGAAAT TGTCTCCATC TGGATCCTGT CCTTTATCCT GGCCATTCCT GAAGCGATTG GCTTCGTCAT GGTACCCTTT GAATATAGGG GTGAACAGCA TAAAACCTGT ATGCTCAATG CCACATCAAA ATTCATGGAG TTCTACCAAG ATGTAAAGGA CTGGTGGCTC TTCGGGTTCT ATTTCTGTAT GCCCTTGGTG TGCACTGCGA TCTTCTACAC CCTCATGACT TGTGAGATGT TGAACAGAAG GAATGGCAGC TTGAGAATTG CCCTCAGTGA ACATCTTAAG CAGCGTCGAG AAGTGGCAAA AACAGTTTTC TGCTTGGTTG TAATTTTTGC TCTTTGCTGG TTCCCTCTTC ATTTAAGCCG TATATTGAAG AAAACTGTGT ATAACGAGAT GGACAAGAAC CGATGTGAAT TACTTAGTTT CTTACTGCTC ATGGATTACA TCGGTATTAA CTTGGCAACC ATGAATTCAT GTATAAACCC CATAGCTCTG TATTTTGTGA GCAAGAAATT TAAAAATTGT

TTCCAGTCAT GCCTCTGCTG CTGCTGTTAC CAGTCCAAAA GTCTGATGAC CTCGGTCCCC ATGAACGGAA CAAGCATCCA GTGGAAGAAC CACGATCAAA ACAACCACAA CACAGACCGG AGCAGCCATA AGGACAGCAT GAACTGACCA CCCTTAGAAG CACTCCTCGG TACTCCCATA ATCCTCTCGG AGAAAAAAAT CACAAGGCAA CTGTGAGTCC GGGAATCTCT TCTCTGATCC TTCTTCCTTA ATTCACTCCC ACACCCAAGA AGAAATGCTT TCCAAAACCG CAAGGGTAGA CTGGTTTATC CACCCACAAC ATCTACGAAT CGTACTTCTT TAATTGATCT AATTTACATA TTCTGCGTGT TGTATTCAGC ACTAAAAAAT GGTGGGAGCT GGGGGAGAAT GAAGACTGTT AAATGAAACC AGAAGGATAT TTACTACTTT TGCATGAAAA TAGAGCTTTC AAGTACATGG CTAGCTTTTA TGGCAGTTCT GGTGAATGTT CAATGGGAAC TGGTCACCAT GAAACTTTAG AGATTAACGA

CAAGATTTTC TACTTTTTTT AAGTGATTTT TTTGTCCTTC AGCCAAACAC AATATGGGCT CAAGTCACTT TTATTTGAAA TGTCATTTGG TGCCAGTATC CCGAATTC-3'

(FRAG NO ) (SEQ ID NO 12383)

5'-GAATTCGGGA AAAAGTGAAG GTGTAAAAGC AGCACAAGTG CAATAAGAGA TATTTCCTCA AATTTGCCTC AAGATGGAAA CCCTTTGCCT CAGGGCATCC TTTTGGCTGG CACTGGTTGG ATGTGTAATC AGTGATAATC CTGAGAGATA CAGCACAAAT CTAAGCAATC ATGTGGATGA TTTCACCACT TTTCGTGGCA CAGAGCTCAG CTTCCTGGTT ACCACTCATC AACCCACTAA TTTGGTCCTA CCCAGCAATG GCTCAATGCA CAACTATTGC CCACAGCAGA CTAAAATTAC TTCAGCTTTC AAATACATTA

ACACTGTGAT ATCTTGTACT ATTTTCATCG TGGGAATGGT GGGGAATGCA ACTCTGCTCA GGATCATTTA CCAGAACAAA TGTATGAGGA ATGGCCCCAA CGCGCTGATA GCCAGTCTTG CCCTTGGAGA CCTTATCTAT GTGGTCATTG ATCTCCCTAT CAATGTATTT AAGCTGCTGG CTGGGCGCTG GCCTTTTGAT CACAATGACT TTGGCGTATT TCTTTGCAAG CTGTTCCCCT TTTTGCAGAA GTCCTCGGTG GGGATCACCG TCCTCAACCT CTGCGCTCTT AGTGTTGACA GGTACAGAGC AGTTGCCTCC TGGAGTCGTG TTCAGGGAAT TGGGATTCCT TTGGTAACTG CCATTGAAAT TGTCTCCATC TGGATCCTGT CCTTTATCCT GGCCATTCCT GAAGCGATTG GCTTCGTCAT GGTACCCTTT GAATATAGGG GTGAACAGCA TAAAACCTGT ATGCTCAATG CCACATCAAA ATTCATGGAG TTCTACCAAG ATGTAAAGGA CTGGTGGCTC TTCGGGTTCT ATTTCTGTAT

GCCCTTGGTG TGCACTGCGA TCTTCTACAC CCTCATGACT TGTGAGATGT TGAACAGAAG GAATGGCAGC TTGAGAATTG CCCTCAGTGA ACATCTTAAG CAGCGTCGAG AAGTGGCAAA AACAGTTTTC TGCTTGGTTG TAATTTTTGC TCTTTGCTGG TTCCCTCTTC ATTTAAGCCG TATATTGAAG AAAACTGTGT ATAACGAGAT GGACAAGAAC CGATGTGAAT TACTTAGTTT CTTACTGCTC ATGGATTACA TCGGTATTAA CTTGGCAACC ATGAATTCAT GTATAAACCC CATAGCTCTG TATTTTGTGA GCAAGAAATT TAAAAATTGT TTCCAGTCAT GCCTCTGCTG CTGCTGTTAC CAGTCCAAAA GTCTGATGAC CTCGGTCCCC ATGAACGGAA CAAGCATCCA GTGGAAGAAC CACGATCAAA ACAACCACAA CACAGACCGG AGCAGCCATA AGGACAGCAT GAACTGACCA CCCTTAGAAG CACTCCTCGG TACTCCCATA ATCCTCTCGG AGAAAAAAAT CACAAGGCAA

CTGTGAGTCC GGGAATCTCT TCTCTGATCC TTCTTCCTTA ATTCACTCCC ACACCCAAGA AGAAATGCTT TCCAAAACCG CAAGGGTAGA CTGGTTTATC CACCCACAAC ATCTACGAAT CGTACTTCTT TAATTGATCT AATTTACATA TTCTGCGTGT TGTATTCAGC ACTAAAAAAT GGTGGGAGCT GGGGGAGAAT GAAGACTGTT AAATGAAACC AGAAGGATAT TTACTACTTT TGCATGAAAA TAGAGCTTTC AAGTACATGG CTAGCTTTTA TGGCAGTTCT GGTGAATGTT CAATGGGAAC TGGTCACCAT GAAACTTTAG AGATTAACGA CAAGATTTTC TACTTTTTTT AAGTGATTTT TTTGTCCTTC AGCCAAACAC AATATGGGCT CAAGTCACTT TTATTTGAAA TGTCATTTGG TGCCAGTATC CCGAATTC-3' (FRAG NO ) (SEQ DD NO 11851)

5'-GAATTCGGGA AAAAGTGAAG GTGTAAAAGC AGCACAAGTG CAATAAGAGA TATTTCCTCA AATTTGCCTC AAGATGGAAA CCCTTTGCCT CAGGGCATCC TTTTGGCTGG CACTGGTTGG ATGTGTAATC AGTGATAATC CTGAGAGATA CAGCACAAAT CTAAGCAATC ATGTGGATGA TTTCACCACT TTTCGTGGCA CAGAGCTCAG CTTCCTGGTT ACCACTCATC AACCCACTAA TTTGGTCCTA CCCAGCAATG GCTCAATGCA CAACTATTGC CCACAGCAGA CTAAAATTAC TTCAGCTTTC AAATACATTA ACACTGTGAT ATCTTGTACT ATTTTCATCG TGGGAATGGT GGGGAATGCA ACTCTGCTCA GGATCATTTA CCAGAACAAA TGTATGAGGA ATGGCCCCAA CGCGCTGATA GCCAGTCTTG CCCTTGGAGA CCTTATCTAT GTGGTCATTG ATCTCCCTAT CAATGTATTT AAGCTGCTGG CTGGGCGCTG GCCTTTTGAT CACAATGACT TTGGCGTATT

TCTTTGCAAG CTGTTCCCCT TTTTGCAGAA GTCCTCGGTG GGGATCACCG TCCTCAACCT CTGCGCTCTT AGTGTTGACA GGTACAGAGC AGTTGCCTCC TGGAGTCGTG TTCAGGGAAT TGGGATTCCT TTGGTAACTG CCATTGAAAT TGTCTCCATC TGGATCCTGT CCTTTATCCT GGCCATTCCT GAAGCGATTG GCTTCGTCAT GGTACCCTTT GAATATAGGG GTGAACAGCA TAAAACCTGT ATGCTCAATG CCACATCAAA ATTCATGGAG TTCTACCAAG ATGTAAAGGA CTGGTGGCTC TTCGGGTTCT ATTTCTGTAT GCCCTTGGTG TGCACTGCGA TCTTCTACAC CCTCATGACT TGTGAGATGT TGAACAGAAG GAATGGCAGC TTGAGAATTG CCCTCAGTGA ACATCTTAAG CAGCGTCGAG AAGTGGCAAA AACAGTTTTC TGCTTGGTTG TAATTTTTGC TCTTTGCTGG TTCCCTCTTC ATTTAAGCCG TATATTGAAG AAAACTGTGT ATAACGAGAT GGACAAGAAC

CGATGTGAAT TACTTAGTTT CTTACTGCTC ATGGATTACA TCGGTATTAA CTTGGCAACC ATGAATTCAT GTATAAACCC CATAGCTCTG TATTTTGTGA GCAAGAAATT TAAAAATTGT TTCCAGTCAT GCCTCTGCTG CTGCTGTTAC CAGTCCAAAA GTCTGATGAC CTCGGTCCCC ATGAACGGAA CAAGCATCCA GTGGAAGAAC CACGATCAAA ACAACCACAA CACAGACCGG AGCAGCCATA AGGACAGCAT GAACTGACCA CCCTTAGAAG CACTCCTCGG TACTCCCATA ATCCTCTCGG AGAAAAAAAT CACAAGGCAA CTGTGAGTCC GGGAATCTCT TCTCTGATCC TTCTTCCTTA ATTCACTCCC ACACCCAAGA AGAAATGCTT TCCAAAACCG CAAGGGTAGA CTGGTTTATC CACCCACAAC ATCTACGAAT CGTACTTCTT TAATTGATCT AATTTACATA TTCTGCGTGT TGTATTCAGC ACTAAAAAAT GGTGGGAGCT GGGGGAGAAT GAAGACTGTT AAATGAAACC AGAAGGATAT TTACTACTTT TGCATGAAAA TAGAGCTTTC AAGTACATGG CTAGCTTTTA TGGCAGTTCT GGTGAATGTT CAATGGGAAC TGGTCACCAT GAAACTTTAG AGATTAACGA CAAGATTTTC TACTTTTTTT AAGTGATTTT TTTGTCCTTC AGCCAAACAC AATATGGGCT CAAGTCACTT TTATTTGAAA TGTCATTTGG TGCCAGTATC

CCGAATTC-3'(FRAG NO ) (SEQ ID NO 11839) 5'-GCCACCATGG AAACCCTTTG CCTCAGGGCA TCCTTTTGGC TGGCACTGGT TGGATGTGTA ATCAGTGATA ATCCTGAGAG ATACAGCACA AATCTAAGCA

ATCATGTGGA TGATTTCACC ACTTTTCGTG GCACAGAGCT CAGCTTCCTG GTTACCACTC ATCAACCCAC TAATTTGGTC CTACCCAGCA ATGGCTCAAT GCACAACTAT TGCCCACAGC AGACTAAAAT TACTTCAGCT TTCAAATACA TTAACACTGT GATATCTTGT ACTATTTTCA TCGTGGGAAT GGTGGGGAAT GCAACTCTGC TCAGGATCAT TTACCAGAAC AAATGTATGA GGAATGGCCC CAACGCGCTG ATAGCCAGTC TTGCCCTTGG AGACCTTATC TATGTGGTCA TTGATCTCCC TATCAATGTA TGGCTGGGCG CTGGCCTTTT GATCACAATG ACTTTGGCGT ATTTCTTTGC AAGCTGTTCC CCTTTTTGCA GAAGTCCTCG GTGGGGATCA CCGTCCTCAA CCTCTGCGCT CTTAGTGTTG ACAGGTACAG AGCAGTTGCC TCCTGGAGTC GTGTTCAGGG AATTGGGATT CCTTTGGTAA CTGCCATTGA AATTGCCTCC ATCTGGATCC TGTCCTTTAT CCTGGCCATT

CCTGAAGCGA TTGGCTTCGT CATGGTACCC TTTGAATATA GGGGTGGACA GCATAAAACC TGTATGCTCA ATGCCACATC AAAATTCATG GAGTTCTACC AAGATGTAAA GGACTGGTGG CTCTTCGGGT TCTATTTCTG TATGCCCTTG GTGTGCACTG CGATCTTCTA CACCCTCATG ACTGGTGAGA TGTTGAACAG AAGGAATGGC AGCTTGAGAA TTGCCCTCAG TGAACATCTT AAGCAGCGTC GAGAAGTGGC AAAAACAGTT TTCTGCTTGG TTGTAATTTT TGCTCTTTGC TGGTTCCCTC TTCATTTAAG CCGTATATTG AAGAAAACTG TGTATAACGA GATGGACAAG AACCGATGTG AATTACTTAG TTTCTTACTG CTCATGGATT ACATCGGTAT TAACTTGGCA ACCATGAATT CATGTATAAA CCCCATAGCT CTGTATTTTG TGAGCAAGAA ATTTAAAAAT TGTTTCCAGT CATGCCTCTG CTGCTGCTGT TACCAGTCCA AAAGTCTGAT GACCTCGGTC CCCATGAACG

GAACAAGCAT CCAGTGGAAG AACCACGATC AAAACAACCA CAACACAGAC CGGAGCAGCC ATAAGGACAG CATGAACTGA CCACCCTTAG AAGCACTCCT-3' (FRAG NO _J (SEQ ID NO 12486)

Substance P Antisense Nucleic Acids and Oligonucleotide Antisense Oligonucleotide Fragments

5'-CTGCTGBGGC TTGGGTCTCC GGGCGBTTCT CTGCBGBBGB TGCTCBBBGG GCTCCGGCBG TTCCTCCTTG BTCTGGTCGCT GTCGTBCCBG TCGGBCCBGT BBTTCBGBTC BTCBTTGGCT CCTBTTTCTT CTGCBBBCBG CTGBGTGGBG BCBBGBBBBB BGBCTGCCBB GGCCBCGBGG BTTTTCBTGT TGGBTTTTGC GBCGGBCBGT CCCGCGGGGT

GCTGAGTTTC TCTGGTTCCT CCGBGCGCBC GTGGTCGCTC CGCGTTTCTC TGGTTCCTCC GGTCCCGCGG GGTGCTGTCT GGTCGCTGTC GTGGCTTGGG TCTCCGGGCG

GTTTCCTTCC TTTTCCGC-3' (FRAG NO 1877) (SEQ ID NO 11259)

5'-CTCC GGGCGB-3' (FRAG NO 1878) (SEQ DDNO 11260)

5'-GGCCBCGBGG-3' (FRAG NO 1879) (SEQ ID NO 11261) 5'-GGGTCTCCGGGCG-3' (FRAG NO 1880) (SEQ ID NO 11262)

5'-GGG TCTCCGGGCG G-3' (FRAG NO 1881) (SEQ ID NO 11263)

5'-CGTGGTCGCTCCGC-3' (FRAG NO 1355)(SEQ ID NO 10733)

5'-GTTTCTCTGGTTCCTCCG-3' (FRAG NO 1356)(SEQ DD NO 10734)

5'-GTCCCGCGGGGTGCTG-3' (FRAG NO 1357)(SEQ DD NO 10735) 5'-TCTGGTCGCTGTCGT-3' (FRAG NO 1358)(SEQ ID NO 10736)

5'-GGCTTGGGTCTCCGGGCG-3' (FRAG NO 1359)(SEQ ID NO 10737)

5'-GTTTCCTTCCTTTTCCGC-3' (FRAG NO 1360)(SEQ ID NO 10738)

5'-CTGCTGBGGC TTGGGTCTCC GGGCGBTTCT CTGCBGBBGB TGCTCBBBGG GCTCCGGCBG TTCCTCCTTG BTCTGGTCGCT GTCGTBCCBG TCGGBCCBGT BBTTCBGBTC

BTCBTTGGCT CCTBTTTCTT CTGCBBBCBG CTGBGTGGBG BCBBGBBBBB BGBCTGCCBB GGCCBCGBGG BTTTTCBTGT TGGBTTTTGC GBCGGBCBGT CCCGCGGGGT GCTGAGTTTC TCTGGTTCCT CCGBGCGCB-3' (FRAG NO 1882) (SEQ DD NO 11264)

Substance P Receptor Nucleic Acids and Antisense Oligonucleotide Fragments

5'-GGGCTBBGBT GBTCCBCBTC BCTBCCBCGT TGCCCBCCBC BGBGGTCBCC BCBBTGBCCG TGTBGGCBGC TGCCCBBBGG BCBBTTTGCC BGGCTGGTTG CBCGBBCTGB

TTGGGTTCCG BGGTGTTBGT GGBGBTGTTT GGGGBGBGGT CTGBGTCCBC CGGGBGGBCG TTBTCCBTTT CGBBGCTBGG CGGTBBBGCC CTBCTBTCTG TBCBCBBCCC

CCCTCTGCBG CBGBGTCCTG TCGTGGCGCC TGGGGCTCBG GGTCCGGGC TAAGATGATC CACATCACTA CCACGTTGCC CACCACAGAG GTCACCACAA TGACCGTGTA GGCAGCTGCC CAAAGGACAA TTTGCCAGGC TGGTTGCACG AACTGATTGG GTTCCGAGGT GTTAGTGGAG ATGTTTGGGG AGAGGTCTGA GTCCACCGGG AGGACGTTAT

CCATTTCGAA GCTAGGCGGT AAAGCCCTAC TATCTGTACA CAACCCCCCT CTGCAGCAGA GTCCTGTCGT GGCGCCTGGG GCTCAGGGTC CGTCCTGTCG TGGCGCCTGG

GGCTCTTCTT TTGTGGGCTC TTTGGTGGCT GTGGCTGTGG TCTCTGTGGT TGCTGCCCTG GGTCTGGGGG TGTGGCCTTG GGGCCGTCCT CTGGCTCCTC CTCGTGGGCC

CCC-3' (FRAG NO 1883) (SEQ ID NO 11265)

5'-GGGBGGBCG-3' (FRAG NO 1884) (SEQ DD NO 11266) 5'-GGGTC CG-3' (FRAG NO 1885) (SEQ ED NO 11267)

5-'GGGCC CCC-3' (FRAG NO 1886) (SEQ ID NO 11268)

5'-GTCCTGTCGTGGCGCCTGGGGCTC-3' (FRAG NO 1361)(SEQ IDNO 10739)

5'-TTCTTTTGTGGGCT-3' (FRAG NO 1362)(SEQ ID O 10740)

5'-CTTTGGTGGCTGTGGCTG-3' (FRAG NO 1363)(SEQ ID NO 10741) 5'-TGGTCTCTGTGGTTG-3' (FRAG NO 1364)(SEQ ID NO 10742)

5'-CTGCCCTGGGTCTGG-3' (FRAG NO 1365)(SEQ ID NO 10743)

5'-GGGTGTGGCCTTGGGGCCGTCCTCTGGCTCCTCCTCGTGGGCCCCC (FRAG NO 1366)(SEQ DD NO 10744)

5'-GGGCTAAGAT GATCCACATC ACTACCACGT TGCCCACCAC AGAGGTCACC ACAATGACCG TGTAGGCAGC TGCCCAAAGG ACAATTTGCC AGGCTGGTTG

CACGAACTGA TTGGGTTCCG AGGTGTTAGT GGAGATGTTT GGGGAGAGGT CTGAGTCCAC CGGGAGGACG TTATCCATTTC GAAGCTAGGC GGTAAAGCCC TACTATCTGTA CACAACCCCC CTCTGCAGCA GAGTCCTGTC GTGGCGCCTG GGGCTCAGGGTCC-3'(FRAG NO 1367)(SEQ DD NO 10745)

5'-GGGCTBBGBT GBTCCBCBTC BCTBCCBCGT TGCCCBCCBC BGBGGTCBCC BCBBTGBCCG TGTBGGCBGC TGCCCBBBGG BCBBTTTGCC BGGCTGGTTG CBCGBBCTGB

TTGGGTTCCG BGGTGTTBGT GGBGBTGTTT GGGGBGBGGTC TGBGTCCBCC GGGBGGBCGT TBTCCBTTTC GBBGCTBGGC GGTBBBGCCC TBCTBTCTGTB CBCBBCCCCC

CTCTGCBGCB GBGTCCTGTC GTGGCGCCTG GGGCTCBGGG TCC-3' (FRAG NO 1368) (SEQ DD NO 10746)

Chvmase Antisense Nucleic Acids and Oligonucleotides Antisense Oligonucleotide Fragments 5'-GGBGCTGBTB CTGCBGATTT CBGBGGGBBG BBCCCTGBTB CTCBCCBGCT TCBGCTCTGG BGCBCBBGBG BBBGBGCBGC BGGGGGBGBG GBBGBBGCBG CBTCTTCCCB

GBGBGGCTGC CTGBGCBBBT GCTGGTTTTC CTTTCCBGTC TTGGGTTTTB TBBCTCCCBG BBGGCBBGBG BGGGGCBBGG CGTTTTCTTC TCTCGCTGGT TTTCCTTTCC TGGCAGTGGG TGGGGGTGGG GGTGGGGTGG CTTCCTTGTT CCTGGGGGTG TCCTCTTGCT CTGGGCTTTT CTCCCCTTTT CCTTCCTGTC TGTTTTCCTG GGGCTCTCCT CTGTCTCTGT GTCCTTGCCC TGGCCCTCTT CCCTCTCCTG TCTCCTGTCC CTGTGTTCCG CCCGTCTTCC CTCTCCTGAC CTCCTTTTCC TCCGCTGGGT GGGGCCCTGC CTGTTCTCTG CTCCCTGGCT TGGGGTTTCT TCTGTGTGTC TTCTTCCTCT GTTGGCTGGC TTTCTCCTTC TTTTGTCTTC CTGGGTGCCC CTTCTTCCTT TCTTGGGTCC TTGGTGCTTG GGCTGGG TCCCAGTTAA TACATAATCA ATATGCAATT TATTAATACA TCTCTCCATG

TCCACTCCCC CTGTATCTTG CCATTCTTGA CCTGCATTTC CATCCTCCTT ACCTTCCCTA GAGGCCAACT CATTTTCTTT GAAAAACCTG GCATTTCCCA GAAAAAAAAG TGAAGGGCTG GGAGCTGTCC GTTGTCCTGA TTTGCTCCCT CTGCCCTTGC TTCCAAATGT GGTTGGAAAG AAGCACTATT GAAAAATCCC TAAACGCACC CCTGCAGGGT TGGCTCTACC CTGTAGCCAT GGACACATGC TGTTGATACC ACCTGCCTCA TGAGTCTCAC ATAATTTGCC CTTTCACACT ATCTACCCCA TCAGCCTTAC CAAAACCATA CCTGCATCCT GGGCAGCATC TGCCCTTCAA GAGACTAAGG AATCTCCTTG CAACCAAGAA TGACTAGACC AATGAGACAC CCTTTAAGGC CCCAGCACAA TATAGAAATC CCACAATATG GTAATCCCAG TAAGGAGCTA TCAAGCCATT GCAGGACCAT CTAGAATACA ACTAGAGTAT AGTTCCTTTC AATCCAGGAA CTATACTCTA ACAGCTTGGC

TCACAGGAAC CAGAAGTGAA GATGATGAGG ATCAGGGCTG AGCCTGTGAG CACCAGCTCC ACCACTGACA CCAACCACAG ATTAAACAAG CATCTTGTGG ACCCCTGGGA TGGAAAGAAT AGTTGTTGCC TTATCAACCT CCCCCACAGC CCACACAGAA AAGATAAAAT CATCATGGCT ACAGTGTTAC AGAAGATGAT GACCCAAGGA GTAGGCCTGC CTGAGTGAAT GCTGAGAGTG ATAATGGGAG CAGTAGCATC TCAGAGACTA CAGCAGAAAC CATCCACATA AAGAGCTTTG CCCAAACTTA TGATAAAGGG CACCCTCAGA GACTCTCCCT ACTTTAATAT TAGCCCATTG CAGAAATGGT GAGTGGAAAG AGAAATCTTA GGAAGAACCC CTTAAAAAAG CAAAATGCTT TTTAGGTTTG TGCTGAAGAG CCTGGAAAAG AAATAAGGAC ACACACGCTG AGAAATCTTC CTCCTGCCCC AACACTGGGA TAATCTCCAA GGATCTCTCC ATATCTCATT CTCCTGGATA CACTGTCCAC

TCAGAAATAT TGTGCAGAGT GCAGTAATTC AAAAGTGAGC TATTGTGTTA GGAGTGAAGG CAAGAGTATC GTAAAATAAA TCAAATTTGA AATGAATTCT CTTAAATTGC TTTATAGATG TTTAATGTAA GCCAGCAGCT ATTAAACGAT AAACCTTAAA TTCGAGAAAA ACTTGGTCAT TCAGAAACTA TAGAAACAGG CAGGACTTAT TGCGAGGGCA AACACAGAGT GAGCTCCAGC CTGCTTCAGG AAAATCTGCC AGTGCCATGA AGGATGTACT CTGTCTGCTC CACTGCACTA CTGCTCAGTA TGAGCCCATG CCATCAGCTG TCCCTGACCC ACAGGAGTTC TTTAGAAGAG ACTGGTCAAC AAAAGTTTCT AGGGTGTTTT ATACCTGCCA ACTCGAGGGT TAAAACAAGT TGCATAGAAA TGCTCAATCA AGAAAGACAC AGTCATTACT CAGAGAATAA TAAACAGCCT GGCAGCACAT GAATGAATAG AAAAAAGATG TTACATGCAA AGCATGAAAT AACCAAATTC CATAACAGAT

GTTAATCTGT AATGTGTTTA GGAGAATTTA GAGGAAGTAT AAGATTTATT CTTTCATCAA AAAAATTATA GCCAATGAGG ATATATCTAT CAATTATCCA TCAAGTGGTG ATATGGCAGC ACAAGGTAAA ACACAAAGGA ATAAAACCAA CGTTTATTAA GAACCAATCA TGTGGCATTT CACATTGAGC ATCATATTTA ATTCTGAAAA AAATCCTTGT ACTGTATCAT TCTTCATATT TTATGGATGC AGTAACTAAG GCTGAGAACT TTAAAATTTT TCCTAAGTTC AGACACATAG CTAAGTGGCA GAACCAAGAT TCAAACTCAC CCCATCTAAC TGCAGAGCAA ACTGCATGCC TTAAATGTCA AAGTGAATAC TAGCACAGTT AATACAATGT TTGGAAACTC AGAGAAGGAA TGATCCCTCT GCATTATAGT TACTAAOGAA TCATTGCCAT TATTTAAATG CCAGTGCTTC TACATCAGGC CCAAATTTTC TGTCCTACTA ACTGTGAATC AAGACTTGAT TCAACCTCTA CTTGAGTATC

TGCCGCAATG AGAAATCACT TACCTCCACT AACCACACAT TTATTTTATA ACAACAGATT GTTAGTAAGT CCTTTCTTAT ACATACTCAA CAGCTGCTTC CCAAGATGCT GTAGGATTAT GTCTAGAGTC AAACTAGCCA GAAGCAATGT CCAAAATACA CCATAACACT GTGCAGCAAA GGTCCTACTA CCACTTGTTT GGCCCAAACA TTCTAGGCAG CACTGGATAT CTGAATCATC AATTATTTCC ACAAACACTG ACCCCTCTAC CAGTCACCCT CACTAGAAGA ATTAATTCCA CATGATAATA GCTCCCTCAT GTTACTCCCT TCTAAGTCAA ATTGTACACC CCTTTATCTG ATTAACAGAG TCTAAGTCAC ATGACCTAAA TGCAAGAGAA CTGGGAATGG ACGTTTGTGG ATTCTACCTT AGTAAGGCAA AGTTATCATT GGGAATTCCT CTAATACAGG AAGGGTGTTC CAGAGACATT AAGGAGCCAT ATAAATGGAA AATGTCCACT ACAATCCATC ACTTGGTTGC CCCACATCAA

CATTCATTCT TTTGCCACAC TTAAAGTTTC CAAGAACAAA AATTATCCCA CTGAACATAA TCTTTACTAT CTTTTATATA AAGGAAAATT AGACTTGACT CAGCAGAACT GAAATAACCC AGCTCTAACA GTTACTGCTT TTAACTTCAA GTACTGTGTC TCTAGGTGAT ACCTGCTCCA ACAATAGTTT GGTCACATTT TCAATTTGAT ATTCTCTAGT CTCCCAACTT GATAACTGTA CCCTAAACCA TAAAGTTCAC TACCAACATG CTATATATAA AATAACCAAA GGGGGAAGAA GAAAGAGAAA AAGGAAATCT CTTAAAATAC ACAGGTATAC ATATGACAAA GCAAAGAAGG AAATGTGAGC AGATAGTGCA GTCCTCGTTT CTGAAATTGG TCCCCTGACT GGGGCTATAC CTATTCCATT TCCTCACCCT CAGCCAGGCA GGTGGAGCAA AAACTTAAGT CTTGGTGGAT CTGAATCTTG ATGCTGTGGA GCTGTCTTAC TAGCCCCAGA CTACCTGCCT CTCAATTTCT AATTATATCA

GTGAAAGCAA ACAGCTTTGA TTTGTTTAAG CCTCTGATTT TTTGGTCTAA CTGATGTAAG ACCACAAGGA CAAGAGTTCT CCAGCTCCGG ATTCTCTTCT GTTCTGTTAA TGGTGAAATG CCCGAGAGAA GAGTTGCCAA CTTTGGCAAA TAAAAAATAC AGGATTCCAG TTAAATTCAA ATTTAGATAA ACAACAATTT TTTAGTATTA GTGTGTCCCA TTCAATATTT GGACATACTT AACTAAAAAA TGATTTGTTG TTCATCTGAA ATACAAATTT AACTGGGCAT TCTGAATATT CTCTGGCAAC CCCCGAGAGA GTGAAGAAAG TGGTACAAGG ACACTTAAGA AGACCAGATT TGAAAAGACA TTACGGATGT GTTTAAATGT CTTATTCTAG AGAGAGTTAG AGCTGTAGGT AGAACTTGGG AAATTAAGTT AAAAGCAGAC ACAGAGACCT GGCCAATATA TACTAAGGAG TGGATCACTC TGGTCACAAG CCCAACCTGA GACCAAGGGC ATAGTGAGAT GATTTGGGAA AGGCACTTAT ACACTACTCA TCCCCGTCTT TGAACTAAAT GCCTTATAAA TCTCCAAGAG AAATGACAGT CCACCATGTG GACTGCTTTC TGTAAGTCCA GGGAAAATAA AAGCTATGTG CTTGAAACCC ACTTCTGATA TTATAAGGTG TGTGATCTTT GTCATGTTAA TGGGTCTGAG TATCAATTCT ACAATTGTAA AGTGACAGTA ATGGTGTGTC CCCAGGTTGT TGTGGAAAGC TTGATTCTTA ATGCAACAGT AGGAAACCCC AGCCTCTCTG GAGCAAACAC CCTTCTACAT CTTTACTTCC CCTGCACATT GGCAGGACTC TATTCCTCTA

TTTCTCTCTA GTGCTAGAGC AGAAAGGGAC CTTGATTTGA TATCAGGAAA ATCTATTTCT GAACCATAAG CTATGATAGC TGATTTAAAA AATTGACTAT CATGACATGA TAATGATCAT AATGGTAATA CATATTGATA GGGTTGCCGT GAAAGTAATA ATATATCTAA GAGTTGTGAC AATATATGAT ACGCCTAGAC TCTCAGAAAA TGCTAATTOC AATCCCAATT GCTCTTTGCA TAAAGTTCTG TCCTAGGGTC TGTTCTTTTC CCACATCTAC CCTCCTTGGA TCTCTCTTCT GTCTTTTTCA TGTGGTTCAG AGGAGGAGAG AGATCCAGGT CAATGTTTTT CAAATTACAA GGAATTATCA TTTAAATGGG GAAGAAGCTC AAGTTTTGAC GTGTAGTGGA ATTGGAGTGG AGTGGAGTGG AATGGAAACT AACAGGAAGA CACTGCACAT GGTTAAGATA AAGATTGTTT CCTGAAACCT TTAATTTGTG CTTACATACT CACACATACA TATGTGCATG CACTGGGACT CTGCAATATG

CATTTCTGAC TATGGAACAT AGCCATAAAA GTCTTTGCAC TGAACGTTCA GTGGGCCTTT CACAAGCTGC CCTAATTGGG AAAGAAAAAC ATGGTCCCTC CATTTCCTGC CCCCAACTCC AGAAAAGTCA CCATAGTTGA GGGTACATCT GAGAAGCCAG CACTTGGGAG TTCAGGGCTC AAGTTCCTTT CTAGAAAAAC ACTGGGTGAT TCTAGGGGAA CTTCCGATCA GAAACAGCCA ATTCAGAGTG AGAGAAGAAA ACGTGACCAT GCAGTTCCTG TGGTTACCAG CCTTGCCCCT CTCTTGCCTT CTGGGAGTTA TAAAACCCAA GACTGGAAAG GAAAACCAGC ATTTGCTCAG GCAGCCTCTC TGGGAAGATG CTGCTTCTTC CTCTCCCCCT GCTGCTCTTT CTCTTGTGCT CCAGAGCTGA AGCTGGTGAG TATCAGGGTT CTTCCCTCTG AAATCTGCAG TATCAGCTCC TGAAACAAAG ATGTTTAGTC TGAAATAGCT GACTCCTAAA CAGGGTTCCA AGATCTCTCT TCAAGAGTCC

CACAGAGGAA ATTTCCACTT GGGATGTGTG CCACCCCACC CCCACCCCCA CCCACTGCCA TTCTCTACAG CCTAGGACAC CCCCAGGAAC AAGGAATTTC ACCTCAATTG TAGAAAAGCC CAGAGCAAGT GGAAGGAAAA GGGGTATCCC CAGGAAAACA GACATGTCCT CTTAATCTTC TGAGCATCAG GGCTACCCAT TACTTTGTGA CTTTCTCACT CTGTGACCAT GCTCAAGAGC TATGGAGAAA TCTAAAACAG GAACCTGGAC AGTGGGTCCT ACACAGAGAC AGAGGAGAGT GGGCCAGGGC AAGGTGGGAG TGGGAGAAGT CTGAGATGAA AACATCAGAA TGGAGCAGAG GCAAGAATGA GATTTCACCT GGGAGGTTAT GGGTGGGGAA AGATACGAAA TACAGGAGAC AGGAGAGGGA AGATGGGCGG AACACAGGGT GAGAATGAGA TTCCAGGGAA GCCTAGCTCA GCTTTAACCC AATTTGTCCA TTCATTGGAG AGAGTATCTA TGGCCGTGTT

CAAACCCTGG GGTGCTCTGT TCCAGGGGAG ATCATCGGGG GCACAGAATG CAAGCCACAT TCCCGCCCCT ACATGGCCTA CCTGGAAATT GTAACTTCCA ACGGTCCCTC AAAATTTTGT GGTGGTTTCC TTATAAGACG GAACTTTGTG CTGACGGCTG CTCATTGTGC AGGAAGGTGA GACAACAGGG TCTATTTATC TCCAAATGGG AGATGAACAA CCAGAGTAGC ATCCAGGAAT ACACCTGCAC TGGGGACTGA AGAGGGGGTC CTGGGTCTTG TCAACTTTCA GGAGAGGGAA GACTTTGGGC TGAAAGACTT TAGTCTGTGT TTGAATAGTT CCTTGAGCCT CAGTCACTGA GCTAAGCTCC CTTCGGAGGA AAAGGAGGTC CTGTCCGAAG GTCCCTCTTG TTGCAGTAGC ACCCCTCACC CCTACCCAAC TCAAGACACA CGGCTCACTT TTCAGGGCCC CACCCAGTCT CAGGGCCACT TCCTCTATGG CCTTTTCAAG AACACTGGCT CTAGTTCTCA GGGTCCTGAA CCCATCATTT

TATGGGAGCA GAGAACAGGT CTACATAAGA CCCCCACTTT CCCGTTTTAA CTGATATCTC CTGCTTCAGG GGCTGGCCCT CATGCAGGGT TCCCTGAATT AGGAAGTGTG AACCCTGTCC CCTGAGTCCT CCCTGGCCTG TTCAGTCCCC AGCAATTCCA GGGGTCGTAG AAATTGTGTC TGTTTCCTGA GAAAGCTCTT TCATGAGTTA AGCCTGAGCC CTCAAATGCC ACAAGTGGCC CATGAAAAGG GAGATGGGTA GAGTCCGGCN ACCCAGTGAC AGAGTTTAGT CCTCTTTTCT CAGAATGAGC TCACCTCAGA AGAAACCCCA AGCCATCACT GTCGCCTCCT TTTCCTTCCT TCTTCCTCAC AGCAGGTCTA TAACAGTCAC CCTTGGAGCC CATAACATAA CAGAGGAAGA AGACACATGG CAGAAGCTTG AGGTTATAAA GCAATTCCGT CATCCAAAAT ATAACACTTC TACTCTTCAC CACGATATCA TGTTACTAAA GGTGACAACA CCTCTCTTCT CCCTTTCCAC TTCCCATTCT

CCTAAGCTTC TCCTTCAGGT CCTCATTGCC CTGAATTTTT CTTAGGACTT GGCTATAACA TGAAGCTACT CACCCTGTCC CTCCCTGATC ACCTCCAACT GTCCAGAGCC CATTTCGAGG ACTGACAGTC CTTCATTCCC TTCACAGTTG AAGGAGAAAG CCAGCCTGAC CCTGGCTGTG GGGACACTCC CCTTCCCATC ACAATTCAAC TTTGTCCCAC CTGGGAGAAT GTGCCGGGTG GCTGGCTGGG GAAGAACAGG TGTGTTGAAG CCGGGCTCAG ACACTCTGCA AGAGGTGAAG CTGAGACTCA TGGATCCCCA GGCCTGCAGC CACTTCAGAG ACTTTGACCA CAATCTTCAG CTGTGTGTGG GCAATCCCAG GAAGACAAAA TCTGCATTTA AGGTGATCCT CCAACTAGGT TTCCTCTCCA AAACTCACTG TTCAGGGACC TGAATGCTCT TAGAAGGAGA TGGGGTCAGC AGGTTGTCAG TCAGGTGACA GGGTGAGCAT CACAGGAATT GCTGTCCTCC CGTGGTCCAA

GACAGCCTCT GACCATCCAT TCCAGTCTAC TGCACTGGGG GCATGGGGTG ACTGTGGAGA ATGTGGATGA CGGTCCCAAG AAAGGAAGAA GGGGCATCAG AACTAGATGT ATAAGTGAGG AGCTCCACCT CCTGGGTCTG ACTTTAGGTC TCACTGTGAC TCCAAGCTGG CTGGCAGACA GGAGTGGAGG ACTTCCCGGG CTCACCTTCT TCTCTCTCTC CTCCCCCTAC AGGGAGACTC TGGGGGCCCT CTTCTGTGTG CTGGGGTGGC CCAGGGCATC GTATCCTATG GACGGTCGGA TGCAAAGCCC CCTGCTGTCT TCACCCGAAT CTCCCATTAC CGGCCCTGGA TCAACCAGAT CCTGCAGGCA AATTAATCCT GGATCCTGAG CCAGCCTGAA GGGAAGCTGG AACTGGACCT TAGCAGCAAA GTGTGTGCAA CTCATTCTGG TTCTACCCTT GGTTCCCTCA GCCACAACCC TAAGCCTCCA AGAGGTCTCC TACAGGTAAC AGAACTTTCA ATAAACTTCA GTGAAGACAC

AGCTTCTAGT CGTGAGTGTG TGTCCCTCTC TGCTGCTCTC TTCTCCTGCA CATGTGACCT GATTCCCAGC CCAAGCACCA AGGA ATCATCGGGG GCACAGAATC CAAGCCACAT TCCCGCCCCT ACATGGCCTA CCTGGAAATT GTAACTTCCA ACGGTCCCTC AAAATTTTGT GGTGGTTTCC TTATAAGACG GAACTTTGTG CTGACGGCTG CTCATTGTGC AGGAAGGTCT ATAACAGTCA CCCTTGGAGC CCATAACATA ACAGAGGAAG AAGACACATG GCAGAAGCTT GAGGTTATAA AGCAATTCCG TCATCCAAAA TATAACACTT CTACTCTTCA CCACGATATC ATGTTACTAA AGTTGAAGGA GAAAGCCAGC CTGACCCTGG CTGTGGGGAC ACTCCCCTTC CCATCACAAT TCAACTTTGT CCCACCTGGG AGAATGTGCC GGGTGGCTGG GTGGGGAAGA ACAGGTGTGT TGAAGCCGGG CTCAGACACT CTGCAAGAGG TGAAGCTGAG ACTCATGGAT

CCCCAGGCCT GCAGCCACTT CAGAGACTTT GACCACAATC TTCAGCTGTG TGTGGGCAAT CCCAGGAAGA CAAAATCTGC ATTTAAGGGA GACTCTGGGG GCCCTCTTCT GTGTGCTGGG GTGGCCCAGG GCATCGTATC CTATGGACGG TCGGATGCAA AGCCCCCTGC TGTCTTCACC CGAATCTCCC ATTACCGGCC CTGGATCAAC CAGATCCTGC AGGCAAATTA A-3' (FRAG NO 1887) (SEQ ID NO 12384) 5'-ATCATCGGGG GCACAGAATC CAAGCCACAT TCCCGCCCCT ACATGGCCTA CCTGGAAATT GTAACTTCCA ACGGTCCCTC AAAATTTTGT GGTGGTTTCC TTATAAGACG GAACTTTGTG CTGACGGCTG CTCATTGTGC AGGAAGGTCT ATAACAGTCA CCCTTGGAGC CCATAACATA ACAGAGGAAG AAGACACATG GCAGAAGCTT GAGGTTATAA

AGCAATTCCG TCATCCAAAA TATAACACTT CTACTCTTCA CCACGATATC ATGTTACTAA AGTTGAAGGA GAAAGCCAGC CTGACCCTGG CTGTGGGGAC ACTCCCCTTC CCATCACAAT TCAACTTTGT CCCACCTGGG AGAATGTGCC GGGTGGCTGG CTGGGGAAGA ACAGGTGTGT TGAAGCCGGG CTCAGACACT CTGCAAGAGG TGAAGCTGAG ACTCATGGAT CCCCAGGCCT GCAGCCACTT CAGAGACTTT GACCACAATC TTCAGCTGTG TGTGGGCAAT CCCAGGAAGA CAAAATCTGC ATTTAAGGGA GACTCTGGGG GCCCTCTTCT GTGTGCTGGG GTGGCCCAGG GCATCGTATC CTATGGACGG TCGGATGCAA AGCCCCCTGC TGTCTTCACC CGAATCTCCC ATTACCGGCC CTGGATCAAC CAGATCCTGC AGGCAAATTA A-3'(FRAG NO )(SEQ ID NO 11837)

5'-TCCCAGTTAA TACATAATCA ATATGCAATT TATTAATACA TCTCTCCATG TCCACTCCCC CTGTATCTTG CCATTCTTGA CCTGCATTTC CATCCTCCTT ACCTTCCCTA GAGGCCAACT CATTTTCTTT GAAAAACCTG GCATTTCCCA GAAAAAAAAG TGAAGGGCTG GGAGCTGTCC GTTGTCCTGA TTTGCTCCCT CTGCCCTTGC TTCCAAATGT GGTTGGAAAG AAGCACTATT GAAAAATCCC TAAACGCACC CCTGCAGGGT TGGCTCTACC CTGTAGCCAT GGACACATGC TGTTGATACC ACCTGCCTCA TGAGTCTCAC ATAATTTGCC CTTTCACACT ATCTACCCCA TCAGCCTTAC CAAAACCATA CCTGCATCCT GGGCAGCATC TGCCCTTCAA GAGACTAAGG AATCTCCTTG CAACCAAGAA TGACTAGACC AATGAGACAC CCTTTAAGGC CCCAGCACAA TATAGAAATC CCACAATATG GTAATCCCAG TAAGGAGCTA TCAAGCCATT GCAGGACCAT CTAGAATACA

ACTAGAGTAT AGTTCCTTTC AATCCAGGAA CTATACTCTA ACAGCTTGGC TCACAGGAAC CAGAAGTGAA GATGATGAGG ATCAGGGCTG AGCCTGTGAG CACCAGCTCC ACCACTGACA CCAACCACAG ATTAAACAAG CATCTTGTGG ACCCCTGGGA TGGAAAGAAT AGTTGTTGCC TTATCAACCT CCCCCACAGC CCACACAGAA AAGATAAAAT CATCATGGCT ACAGTGTTAC AGAAGATGAT GACCCAAGGA GTAGGCCTGC CTGAGTGAAT GCTGAGAGTG ATAATGGGAG CAGTAGCATC TCAGAGACTA CAGCAGAAAC CATCCACATA AAGAGCTTTG CCCAAACTTA TGATAAAGGG CACCCTCAGA GACTCTCCCT ACTTTAATAT TAGCCCATTG CAGAAATGGT GAGTGGAAAG AGAAATCTTA GGAAGAACCC CTTAAAAAAG CAAAATGCTT TTTAGGTTTG TGCTGAAGAG CCTGGAAAAG AAATAAGGAC ACACACGCTG AGAAATCTTC CTCCTGCCCC

AACACTGGGA TAATCTCCAA GGATCTCTCC ATATCTCATT CTCCTGGATA CACTGTCCAC TCAGAAATAT TGTGCAGAGT GCAGTAATTC AAAAGTGAGC TATTGTGTTA GGAGTGAAGG CAAGAGTATC GTAAAATAAA TCAAATTTGA AATGAATTCT CTTAAATTGC TTTATAGATG TTTAATGTAA GCCAGCAGCT ATTAAACGAT AAACCTTAAA TTCGAGAAAA ACTTGGTCAT TCAGAAACTA TAGAAACAGG CAGGACTTAT TGCGAGGGCA AACACAGAGT GAGCTCCAGC CTGCTTCAGG AAAATCTGCC AGTGCCATGA AGGATGTACT CTGTCTGCTC CACTGCACTA CTGCTCAGTA TGAGCCCATG CCATCAGCTG TCCCTGACCC ACAGGAGTTC TTTAGAAGAG ACTGGTCAAC AAAAGTTTCT AGGGTGTTTT ATACCTGCCA ACTCGAGGGT TAAAACAAGT TGCATAGAAA TGCTCAATCA AGAAAGACAC AGTCATTACT CAGAGAATAA TAAACAGCCT GGCAGCACAT

GAATGAATAG AAAAAAGATG TTACATGCAA AGCATGAAAT AACCAAATTC CATAACAGAT GTTAATCTGT AATGTGTTTA GGAGAATTTA GAGGAAGTAT AAGATTTATT CTTTCATCAA AAAAATTATA GCCAATGAGG ATATATCTAT CAATTATCCA TCAAGTGGTG ATATGGCAGC ACAAGGTAAA ACACAAAGGA ATAAAACCAA CGTTTATTAA GAACCAATCA TGTGGCATTT CACATTGAGC ATCATATTTA ATTCTGAAAA AAATCCTTGT ACTGTATCAT TCTTCATATT TTATGGATGC AGTAACTAAG GCTGAGAACT TTAAAATTTT TCCTAAGTTC AGACACATAG CTAAGTGGCA GAACCAAGAT TCAAACTCAC CCCATCTAAC TGCAGAGCAA ACTGCATGCC TTAAATGTCA AAGTGAATAC TAGCACAGTT AATACAATGT TTGGAAACTC AGAGAAGGAA TGATCCCTCT GCATTATAGT TACTAAGGAA TCATTGCCAT TATTTAAATG CCAGTGCTTC TACATCAGGC

CCAAATTTTC TGTCCTACTA ACTGTGAATC AAGACTTGAT TCAACCTCTA CTTGAGTATC TGCCGCAATG AGAAATCACT TACCTCCACT AACCACACAT TTATTTTATA ACAACAGATT GTTAGTAAGT CCTTTCTTAT ACATACTCAA CAGCTGCTTC CCAAGATGCT GTAGGATTAT GTCTAGAGTC AAACTAGCCA GAAGCAATGT CCAAAATACA CCATAACACT GTGCAGCAAA GGTCCTACTA CCACTTGTTT GGCCCAAACA TTCTAGGCAG CACTGGATAT CTGAATCATC AATTATTTCC ACAAACACTG ACCCCTCTAC CAGTCACCCT CACTAGAAGA ATTAATTCCA CATGATAATA GCTCCCTCAT GTTACTCCCT TCTAAGTCAA ATTGTACACC CCTTTATCTG ATTAACAGAG TCTAAGTCAC ATGACCTAAA TGCAAGAGAA CTGGGAATGG ACGTTTGTGG ATTCTACCTT AGTAAGGCAA AGTTATCATT GGGAATTCCT CTAATACAGG AAGGGTGTTC CAGAGACATT

AAGGAGCCAT ATAAATGGAA AATGTCCACT ACAATCCATC ACTTGGTTGC CCCACATCAA CATTCATTCT TTTGCCACAC TTAAAGTTTC CAAGAACAAA AATTATCCCA CTGAACATAA TCTTTACTAT CTTTTATATA AAGGAAAATT AGACTTGACT CAGCAGAACT GAAATAACCC AGCTCTAACA GTTACTGCTT TTAACTTCAA GTACTGTGTC TCTAGGTGAT ACCTGCTCCA ACAATAGTTT GGTCACATTT TCAATTTGAT ATTCTCTAGT CTCCCAACTT GATAACTGTA CCCTAAACCA TAAAGTTCAC TACCAACATG CTATATATAA AATAACCAAA GGGGGAAGAA GAAAGAGAAA AAGGAAATCT CTTAAAATAC ACAGGTATAC ATATGACAAA GCAAAGAAGG AAATGTGAGC AGATAGTGCA GTCCTCGTTT CTGAAATTGG TCCCCTGACT GGGGCTATAC CTATTCCATT TCCTCACCCT CAGCCAGGCA GGTGGAGCAA AAACTTAAGT CTTGGTGGAT

CTGAATCTTG ATGCTGTGGA GCTGTCTTAC TAGCCCCAGA CTACCTGCCT CTCAATTTCT AATTATATCA GTGAAAGCAA ACAGCTTTGA TTTGTTTAAG CCTCTGATTT TTTGGTCTAA CTGATGTAAG ACCACAAGGA CAAGAGTTCT CGAGCTCCGG ATTCTCTTCT GTTCTGTTAA TGGTGAAATG CCCGAGAGAA GAGTTGCCAA CTTTGGCAAA TAAAAAATAC AGGATTCCAG TTAAATTCAA ATTTAGATAA ACAACAATTT TTTAGTATTA GTGTGTCCCA TTCAATATTT GGACATACTT AACTAAAAAA TGATTTGTTO TTCATCTGAA ATACAAATTT AACTGGGCAT TCTGAATATT CTCTGGCAAC CCCCGAGAGA GTGAAGAAAG TGGTACAAGG ACACTTAAGA AGACCAGATT TGAAAAGACA TTACGGATGT GTTTAAATGT CTTATTCTAG AGAGAGTTAG AGCTGTAGGT AGAACTTGGG AAATTAAGTT AAAAGCAGAC ACAGAGACCT GGCCAATATA TACTAAGGAG

TGGATCACTC TGGTCACAAG CCCAACCTGA GACCAAGGGC ATAGTGAGAT GATTTGGGAA AGGCACTTAT ACACTACTCA TCCCCGTCTT TGAACTAAAT GCCTTATAAA TCTCCAAGAG AAATGACAGT CCACCATGTG GACTGCTTTC TGTAAGTCCA GGGAAAATAA AAGCTATGTG CTTGAAACCC ACTTCTGATA TTATAAGGTG TGTGATCTTT GTCATGTTAA TGGGTCTGAG TATCAATTCT ACAATTGTAA AGTGACAGTA ATGGTGTGTC CCCAGGTTGT TGTGGAAAGC TTGATTCTTA ATGCAACAGT AGGAAACCCC AGCCTCTCTG GAGCAAACAC CCTTCTACAT CTTTACTTCC CCTGCACATT GGCAGGACTC TATTCCTCTA TTTCTCTCTA GTGCTAGAGC AGAAAGGGAC CTTGATTTGA TATCAGGAAA ATCTATTTCT GAACCATAAG CTATGATAGC TGATTTAAAA AATTGACTAT CATGACATGA TAATGATCAT AATGGTAATA CATATTGATA GGGTTGCCGT

GAAAGTAATA ATATATCTAA GAGTTGTGAC AATATATGAT ACGCCTAGAC TCTCAGAAAA TGCTAATTCC AATCCCAATT GCTCTTTGCA TAAAGTTCTG TCCTAGGGTC TGTTCTTTTC CCACATCTAC CCTCCTTGGA TCTCTCTTCT GTCTTTTTCA TGTGGTTCAG AGGAGGAGAG AGATCCAGGT CAATGTTTTT CAAATTACAA GGAATTATCA TTTAAATGGG GAAGAAGCTC AAGTTTTGAC GTGTAGTGGA ATTGGAGTGG AGTGGAGTGG AATGGAAACT AACAGGAAGA CACTGCACAT GGTTAAGATA AAGATTGTTT CCTGAAACCT TTAATTTGTG CTTACATACT CACACATACA TATGTGCATG CACTGGGACT CTGCAATATG CATTTCTGAC TATGGAACAT AGCCATAAAA GTCTTTGCAC TGAACGTTCA GTGGGCCTTT CACAAGCTGC CCTAATTGGG AAAGAAAAAC ATGGTCCCTC CATTTCCTGC CCCCAACTCC AGAAAAGTCA CCATAGTTGA GGGTACATCT GAGAAGCCAG CACTTGGGAG TTCAGGGCTC AAGTTCCTTT CTAGAAAAAC ACTGGGTGAT TCTAGGGGAA CTTCCGATCA GAAACAGCCA ATTCAGAGTG AGAGAAGAAA ACGTGACCAT GCAGTTCCTG TGGTTACCAG CCTTGCCCCT CTCTTGCCTT CTGGGAGTTA TAAAACCCAA GACTGGAAAG GAAAACCAGC ATTTGCTCAG GCAGCCTCTC TGGGAAGATG CTGCTTCTTC CTCTCCCCCT GCTGCTCTTT CTCTTGTGCT CCAGAGCTGA AGCTGGTGAG TATCAGGGTT CTTCCCTCTG AAATCTGCAG TATCAGCTCC TGAAACAAAG ATGTTTAGTC TGAAATAGCT GACTCCTAAA CAGGGTTCCA AGATCTCTCT TCAAGAGTCC CACAGAGGAA ATTTCCACTT GGGATGTGTG CCACCCCACC

CCCACCCCCA CCCACTGCCA TTCTCTACAG CCTAGGACAC CCCCAGGAAC AAGGAATTTC ACCTCAATTG TAGAAAAGCC CAGAGCAAGT GGAAGGAAAA GGGGTATCCC CAGGAAAACA GACATGTCCT CTTAATCTTC TGAGCATCAG GGCTACCCAT TACTTTGTGA CTTTCTCACT CTGTGACCAT GCTCAAGAGC TATGGAGAAA TCTAAAACAG GAACCTGGAC AGTGGGTCCT ACACAGAGAC AGAGGAGAGT GGGCCAGGGC AAGGTGGGAG TGGGAGAAGT CTGAGATGAA AACATCAGAA TGGAGCAGAG GCAAGAATGA GATTTCACCT GGGAGGTTAT GGGTGGGGAA AGATACGAAA TACAGGAGAC AGGAGAGGGA AGATGGGCGG AACACAGGGT GAGAATGAGA TTCCAGGGAA GCCTAGCTCA GCTTTAACCC AATTTGTCCA TTCATTGGAG AGAGTATCTA TGGCCGTGTT CAAACCCTGG GGTGCTCTGT TCCAGGGGAG ATCATCGGGG

GCACAGAATG CAAGCCACAT TCCCGCCCCT ACATGGCCTA CCTGGAAATT GTAACTTCCA ACGGTCCCTC AAAATTTTGT GGTGGTTTCC TTATAAGACG GAACTTTGTG CTGACGGCTG CTCATTGTGC AGGAAGGTGA GACAACAGGG TCTATTTATC TCCAAATGGG AGATGAACAA CCAGAGTAGC ATCCAGGAAT ACACCTGCAC TGGGGACTGA AGAGGGGGTC CTGGGTCTTG TCAACTTTCA GGAGAGGGAA GACTTTGGGC TGAAAGACTT TAGTCTGTGT TTGAATAGTT CCTTGAGCCT CAGTCACTGA GCTAAGCTCC CTTCGGAGGA AAAGGAGGTC CTGTCCGAAG GTCCCTCTTG TTGCAGTAGC ACCCCTCACC CCTACCCAAC TCAAGACACA CGGCTCACTT TTCAGGGCCC CACCCAGTCT CAGGGCCACT TCCTCTATGG CCTTTTCAAG AACACTGGCT CTAGTTCTCA GGGTCCTGAA CCCATCATTT TATGGGAGCA GAGAACAGGT CTACATAAGA CCCCCACTTT

CCCGTTTTAA CTGATATCTC CTGCTTCAGG GGCTGGCCCT CATGCAGGGT TCCCTGAATT AGGAAGTGTG AACCCTGTCC CCTGAGTCCT CCCTGGCCTG TTCAGTCCCC AGCAATTCCA GGGGTCGTAG AAATTGTGTC TGTTTCCTGA GAAAGCTCTT TCATGAGTTA AGCCTGAGCC CTCAAATGCC ACAAGTGGCC CATGAAAAGG GAGATGGGTA GAGTCCGGCN ACCCAGTGAC AGAGTTTAGT CCTCTTTTCT CAGAATGAGC TCACCTCAGA AGAAACCCCA AGCCATCACT GTCGCCTCCT TTTCCTTCCT TCTTCCTCAC AGCAGGTCTA TAACAGTCAC CCTTGGAGCC CATAACATAA CAGAGGAAGA AGACACATGG CAGAAGCTTG AGGTTATAAA GCAATTCCGT CATCCAAAAT ATAACACTTC TACTCTTCAC CACGATATCA TGTTACTAAA GGTGACAACA CCTCTCTTCT CCCTTTCCAC TTCCCATTCT CCTAAGCTTC TCCTTCAGGT CCTCATTGCC CTGAATTTTT

CTTAGGACTT GGCTATAACA TGAAGCTACT CACCCTGTCC CTCCCTGATC ACCTCCAACT GTCCAGAGCC CATTTCGAGG ACTGACAGTC CTTCATTCCC TTCACAGTTG AAGGAGAAAG CCAGCCTGAC CCTGGCTGTG GGGACACTCC CCTTCCCATC ACAATTCAAC TTTGTCCCAC CTGGGAGAAT GTGCCGGGTG GCTGGCTGGG GAAGAACAGG TGTGTTGAAG CCGGGCTCAG ACACTCTGCA AGAGGTGAAG CTGAGACTCA TGGATCCCCA GGCCTGCAGC CACTTCAGAG ACTTTGACCA CAATCTTCAG CTGTGTGTGG GCAATCCCAG GAAGACAAAA TCTGCATTTA AGGTGATCCT CCAACTAGGT TTCCTCTCCA AAACTCACTG TTCAGGGACC TGAATGCTCT TAGAAGGAGA TGGGGTCAGC AGGTTGTCAG TCAGGTGACA GGGTGAGCAT CACAGGAATT GCTGTCCTCC CGTGGTCCAA GACAGCCTCT GACCATCCAT TCCAGTCTAC TGCACTGGGG GCATGGGGTG

ACTGTGGAGA ATGTGGATGA CGGTCCCAAG AAAGGAAGAA GGGGCATCAG AACTAGATGT ATAAGTGAGG AGCTCCACCT CCTGGGTCTG ACTTTAGGTC TCACTGTGAC TCCAAGCTGG CTGGCAGACA GGAGTGGAGG ACTTCCCGGG CTCACCTTCT TCTCTCTCTC CTCCCCCTAC AGGGAGACTC TGGGGGCCCT CTTCTGTGTG CTGGGGTGGC CCAGGGCATC GTATCCTATG GACGGTCGGA TGCAAAGCCC CCTGCTGTCT TCACCCGAAT CTCCCATTAC CGGCCCTGGA TCAACCAGAT CCTGCAGGCA AATTAATCCT GGATCCTGAG CCAGCCTGAA GGGAAGCTGG AACTGGACCT TAGCAGCAAA GTGTGTGCAA CTCATTCTGG TTCTACCCTT GGTTCCCTCA GCCACAACCC TAAGCCTCCA AGAGGTCTCC TACAGGTAAC AGAACTTTCA ATAAACTTCA GTGAAGACAC AGCTTCTAGT CGTGAGTGTG TGTCCCTCTC TGCTGCTCTC TTCTCCTGCA CATGTGACCT

GATTCCCAGC CCAAGCACCA AGGA-3' (FRAG NO ) (SEQ ID NO 11836) 5'-GGBGCBCBBG-3' (FRAG NO 1888) (SEQ DDNO 11270) 5'-GBBGCBGC-3' (FRAG NO 1889) (SEQ ID NO 11271) 5'-GGGGCBBGG CG-3' (FRAG NO 1890) (SEQ DD NO 11272) 5'-CGTTTTCTTCTCTC-3' (FRAG NO 1369)(SEQ ID NO 10747)

5'-GCTGGTTTTCCTTTCC-3' (FRAG NO 1370)(SEQ DD NO 10748)

5'-TGGCAGTGGGTGGGGGTGGGGGTGGGGTGGC-3' (FRAG NO 1371)(SEQ DD NO 10749) 5'-TTCCTTGTTCCTGGGGGTGTCCT-3' (FRAG NO 1372)(SEQ ID NO 10750) 5'-CTTGCTCTGGGCTTTTCT-3' (FRAG NO 1373)(SEQ ID NO 10751) 5'-CCCCTTTTCCTTCC-3' (FRAG NO 1374)(SEQ ID NO 10752) [

5'-TGTCTGTTTTCCTGGGG-3' (FRAG NO 1375)(SEQ ID NO 10753) 5'-CTCTCCTCTGTCTCTGTGT-3' (FRAG NO 1376)(SEQ ID NO 10754) 5'-CCTTGCCCTGGCCC-3' (FRAG NO 1377)(SEQ ID NO 10755) 5'-TCTTCCCTCTCCTGTCTCCTGT-3' (FRAG NO 1378)(SEQ ID NO 10756) 5'-CCCTGTGTTCCGCCC-3' (FRAG NO I379)(SEQ ID NO 10757)

5'-GTCTTCCCTCTCCTG-3' (FRAG NO 1380)(SEQ ED NO 10758) 5'-ACCTCCTTTTCCTCCG-3' (FRAG NO 1381)(SEQ ID NO 10759) 5'-CTGGGTGGGGCCCTG-3' (FRAG NO 1382)(SEQ DD NO 10760) 5'-CCTGTTCTCTGCTCCC-3' (FRAG NO 1383)(SEQ ID NO 10761) 5'-TGGCTTGGGGTTTCTTCTG-3' (FRAG NO 1384)(SEQ ID NO 10762)

5'-TGTGTCTTCTTCCTCTGTT-3' (FRAG NO 1385)(SEQ ID NO 10763) 5'-GGCTGGCTTTCTCCTTC-3' (FRAG NO 1386)(SEQ ID NO 10764) 5'-TTTTGTCTTCCTGGG-3' (FRAG NO 1387)(SEQ ID NO 10765) [1397)] 5'-TGCCCCTTCTTCCTTTCTTGGG-3' (FRAG NO 1388)(SEQ ID NO 10766) 5'-TCCTTGGTGCTTGGGCTGGG-3' (FRAG NO 1389)(SEQ DD NO 10767)

5'-GGBGCTGBTB CTGCBGATTT CBGBGGGBBG BBCCCTGBTB CTCBCCBGCT TCBGCTCTGG BGCBCBBGBG BBBGBGCBGC BGGGGGBGBG GBBGBBGCBG CBTCTTCCCB GBGBGGCTGC CTGBGCBBBT GCTGGTTTTC CTTTCCBGTC TTGGGTTTTB TBBCTCCCBG BBGGCBBGBG BGGGGCBBGG-3' (FRAG NO 1891) (SEQ DD NO 11273)

Endothelial Nitric Oxide Synthase Nucleic Acids and Antisense Oligonucleotide Fragments

5'-GCGTCTTGGG GTGCBGGGCC CBTCCTGCTG CGCCTGGGCG CTGCTGTGCG TCCGTCTGCT GGGGGGCCGG GGTGGCTGGG CCCTGCTTGC CGCACGACCC CGGGCCGACC CGAGGCTCGG GGGGCTGTGT TCTGGCGCTG GTGGGCTTGG GCCCCTCTGG GGGCTGGGTT TCCTGCTGCG CCTGGGCGCT GGCGTCTTGG GGTGCGGGGC

CGGGGGGCCG GGGGGCCGCT GTTCGTGGGC CTGGGGGTGC CTGTGGCTGC CGGTTGCCCC GGTTGGTGGC GCCGTCCTGC TGCCGGTCGT TGGCTGGGTC CCCCCGCCCG

TTTCCTGGGG TCCGCGTGGG GTGCTCCGGT TCCTCGTGCC GCTGCTGCCT TGTCTTTCCG GCCGTGGCGG CGTGGTGGTC CGCCCCCCCT GGCCTTCTGC TCGGGGTCTG

GCTGGTTGCC GGTGCCCTTG GCGGCGGTCT TCTTCCTGGT GGCTCTGGGC CCGGCCGGTC TCGGGCGTCT CGTGTTCGCT CTTGTGCTGT TCCGGCCGCT CCTTCCTCTT

CCGCCGCCGC CGCTCCCCGC CCGCTCGTCG CCCTGGCCCG GCCTCCTCCT GGCCGCTGTC TCGGGCGGCG GCCTTGGCGC TCCGTTTGGG GCTGCCTCTG GCGCTTCCGG CCCTCGGCCT GGGCGCTCTC TTCCGCCTGT GCTGGTGGCC CTCGTGGGCC CCTCCTGGCC TCCGGTGTCC TGTGGTCCCC CGGCTGGTGG CCGGGCCGGT TGGGCGGGCG

TGGGCGCCGG CGGGTCCTCC GGGCTGCCCT TCTCCGCCGG GGGTCCCGCG CTCCTGCTGT TCCCTGGGCT CTTCTGCCTC TCTCCTGGGT GGGTGCTGGG TGCCGGGGTC

TCCGGGCTTG CCCCGCGCTG CTGGGCGTTC TGCGGTCTTG GGGTTGTCTG TGGCCCCGCT CGTGTCGCCC TCCGTCGCCC GTCGCCGGCC TCGTCCCCTC CTGGGTGCGC

GGCGGGCTGG TCCTGGCGTT TTGCTCCTTC CTGGGCGTCT TGGGGTGCBG GGCCCBTCCT GCTGCGCCTG GGCGCTGCTG TGCGTCCGTC TGCTGGGGGG CCGGGGTGGC

TGGGCCCTGG TTGCCGCACG ACCCCGGGCC GACCCGAGGC TCGGGGGGCT GTGTTCTGGC GCTGGTGGGC TTGGGCCCCT CTGGGGGCTG GGTTTCCTGC TGCGCCTGGG CGCTGGCGTC TTGGGGTGCG GGGCCGGGGG GCCGGGGGGC CGCTGTTCGT GGGCCTGGGG GTGCCTGTGG CTGCCGGTTG CCCCGGTTGG TGGCGCCGTC

CTGCTGCCGG TCGTTGGCTG GGTCCCCCCG CCCGTTTCCT GGGGTCCGCG TGGGGTGCTC CGGTTCCTCG TGCCGCTGCT GCCTTGTCTT TCCGGCGGTG GCGGCGTGGT

GGTCCGCCCC CCCTGGCCTT CTGCTCGGGG TCTGGCTGGT TGCCGGTGCC CTTGGCGGCG GTCTTCTTCC TGGTGGCTCT GGGCCCGGCC GGTCTCGGGC GTCTCGTGTT

CGCTCTTGTG CTGTTCCGGC CGCTCCTTCC TCTTCCGCCG CCGCCGCTCC CCGCCCGCTC GTCGCCCTGG CCCGGCCTCC TCCTGGCCGC TGTCTCGGGC GGCGGCCTTG

GCGCTCCGTT TGGGGCTGCC TCTGGCGCTT CCGGCCCTCG GCCTGGGCGC TCTCTTCCGC CTGTGCTGGT GGCCCTGGTG GGCCCCTCCT GGCCTCCGGT GTCCTGTGGT CCCCCGGCTG GTGGCCGGGC CGGTTGGGCG GGCGTGGGCG CCGGCGGGTC CTCCGGGCTG CCCTTCTCCG CCGGGGGTCC CGCGCTCCTG CTGTTCCCTG GGCTCTTCTG

CCTCTCTCCT GGGTGGGTGC TGGGTGCCGG GGTCTCCGGG CTTGCCCCGC GCTGCTGGGC GTTCTGCGGT CTTGGGGTTG TCTGTGGCCC CGCTCGTGTC GCCCTCCGTC

GCCCGTCGCC GGCCTCGTCC CCTCCTGGGT GCGCGGCGGG CTGGTCCTGG CGTTTTGCTC CTTCCTGG-3' (FRAG NO 1892) (SEQ ID NO 11274)

5'-GCGGGGCCG-3' (FRAG NO 1893) (SEQ ID NO 11275)

5'-CGGGGGGC-3' (FRAG NO 1894) (SEQ DD NO 11276) 5'-GCGCGGCGGGC-3' (FRAG NO 1895) (SEQ DD NO 11277)

5'-CTGTGCGTCCGTCTGCTGG (FRAG NO 1390)(SEQ ID NO 10768)

GGGGCCGGGGTGGCTGGGCCCTGCTTGCCGC (FRAG NO 1391)(SEQ DD NO 10769)

ACGACCCCGGGCCGACCCGAG (FRAG NO 1392)(SEQ DD NO 10770)

GCTCGGGGGGCTGTGTTCTGGCGCTGGTGGG (FRAG NO 1393)(SEQ ID NO 10771) CTTGGGCCCCTCTGGGGGCTGGGTT (FRAG NO 1394)(SEQ ID NO 10772)

TCCTGCTGCGCCTGGGCGCTG (FRAG NO 1395) (SEQ ED NO 10773)

GCGTCTTGGGGTGC (FRAG NO 1396)(SEQ DD NO 10774)

GGGGCCGGGGGGCCGGOGG (FRAG NO I397)(SEQ ID NO 10775)

GCCGCTGTTCGTGGGCCTGGG (FRAG NO 1398)(SEQ ID NO 10776) GGTGCCTGTGGCTGCC (FRAG NO 1399)(SEQ ED NO 10777)

GGTTGCCCCGGTTGGTGGC (FRAG NO 1400)(SEQ ID NO 10778)

GCCGTCCTGCTGCCGGT (FRAG NO 1401)(SEQ DD NO 10779)

CGTTGGCTGGGTCCCCCCGC (FRAG NO 1402)(SEQ ED NO 10780)

CCGTTTCCTGGGGTCC (FRAG NO 1403)(SEQ DD NO 10781) GCGTGGGGTGCTCC (FRAG NO 1404)(SEQ DD NO 10782)

GGTTCCTCGTGCCG (FRAG NO 1405)(SEQ ID NO 10783)

CTGCTGCCTTGTCTTTCC (FRAG NO 1406)(SEQ DD NO 10784)

GGCCGTGGCGGCGTGGTGGTCC (FRAG NO 1407)(SEQ DD NO 10785)

GCCCCCCCTGGCCTTCTGCTC (FRAG NO 1408)(SEQ ID NO 10786) GGGGTCTGGCTGGT (FRAG NO 1409)(SEQ ED NO 10787)

TGCCGGTGCCCTTGGCGGC (FRAG NO 1410)(SEQ ED NO 10788)

GGTCTTCTTCCTGGTG (FRAG NO 1411)(SEQ EDNO 10789)

GCTCTGGGCCCGGCCGGTCTCGG (FRAG NO 1412)(SEQ ED NO 10790) GCGTCTCGTGTTCG (FRAG NO 1413)(SEQ DD NO 10791)

CTCTTGTGCTGTTCCGGCCG (FRAG NO 1414)(SEQ DD NO 10792)

CTCCTTCCTCTTCCGCCGCC (FRAG NO 1415)(SEQ DD NO 10793)

GCCGCTCCCCGCCC (FRAG NO 1416)(SEQ DD NO 10794)

GCTCGTCGCCCTGGCCC (FRAG NO 1417)(SEQ ID NO 10795) GGCCTCCTCCTGGCCGC (FRAG NO 1418)(SEQ DD NO 10796)

TGTCTCGGGCGGCGGCCTTGGC (FRAG NO 1419)(SEQ ID NO 10797)

GCTCCGTTTGGGGCTG (FRAG NO 1420)(SEQ ID NO 10798)

CCTCTGGCGCTTCC (FRAG NO 1421)(SEQ ID NO 10799)

GGCCCTCGGCCTGGGCGCTC (FRAG NO 1422)(SEQ ID NO 10800) TCTTCCGCCTGTGC (FRAG NO 1423)(SEQ DD NO 10801)

TGGTGGCCCTCGTGG (FRAG NO 1424)(SEQ ID NO 10802)

GCCCCTCCTGGCCTCCGGTGTCC (FRAG NO 1425)(SEQ DD NO 10803)

TGTGGTCCCCCGGCTGGT (FRAG NO 1426)(SEQ ED NO 10804)

GGCCGGGCCGGTTGGGCGGGC (FRAG NO 1427)(SEQ ID NO 10805) GTGGGCGCCGGCGGGTCCTCC (FRAG NO 1428)(SEQ DD NO 10806)

GGGCTGCCCTTCTCC (FRAG NO 1429)(SEQ ID NO 10807)

GCCGGGGGTCCCGC (FRAG NO 1430)(SEQ DD NO 10808)

GCTCCTGCTGTTCCCTGGGCTCTTCTGCC fFRAG NO 1431)(SEQ ID NO 10809)

TCTCTCCTGGGTGGGTGCTGGGTGCCG (FRAG NO 1432)(SEQ DD NO 10810) GGGTCTCCGGGCTTG (FRAG NO 1433)(SEQ ID NO 10811)

CCCCGCGCTGCTGGGCGTTCTGC (FRAG NO 1434)(SEQ ID NO 10812)

GGTCTTGGGGTTGTC (FRAG NO 1435)(SEQ ID NO 10813)

TGTGGCCCCGCTCG (FRAG NO 1436)(SEQ DD NO 10814)

TGTCGCCCTCCGTCGCC (FRAG NO 1437)(SEQ ID NO 10815) CGTCGCCGGCCTCGTCC (FRAG NO 1438)(SEQ ID NO 10816)

CCTCCTGGGTGCGC (FRAG NO 1439)(SEQ ID NO 10817)

GGCGGGCTGGTCCT (FRAG NO 1440)(SEQ DDNO 10818)

GGCGTTTTGCTCCTTCCTGG (FRAG NO 1441)(SEQ DD NO 10819)

5'-GCGTCTTGGGGTGCBGGGCCCBTCCTGCTGCGCCTGGGCGCTG-3'(FRAG NO 1896) (SEQ ID NO 11278) Inducible Nitric Oxide Synthase Nucleic Acids and Antisense Oligonucleotide Fragments

5'-CTGCCCCBGT TTTTGBTCCT CBCBTGCCGT GGGGBGGBCB BTGGCTGCCT CCCCGGGGTT TCTGCTGCTT GCTGCTTCTT TCCCGTCTCC CTTCTTTCCC GTCTCCTTTT TGCCTCTTTG GGTTCCTGTT GTTTCTGGCC TGCTTGGTGG CGGCTTGTGC GTTTCCTCTC TCTTCTCTTG GGTCTCCGCT TCTCGTCCTG CCTTTTCCTG TCTCTGTCGC GCCGTTCCTC CTCCGGCGTC CTCCTGCCCT GTGCTGTTTG CCTCGGGTGG TGCGGGTCCC GGTGCTCCCC CGGCGGGCCG GCTGGTTGCC TGGGCCTGTC TGGTGGGGTG TGGGGCCGCT GGGTTGGGGG TGTGGTGGGC TCTTCTGTGG CCTGTGGGGC TGTTGGTGTC TCTGTGGGCG TGTGCTGGGT CTTGGGGCTT CCTCCCTTGT GCTGGGTGCG GCCTCCCCGC CCCCCTTCTG GGCCGGTGGC CTGGCTCCTT GTGGGCGCTT CTGGCTCTTG CCCTGTCCTT CTTCGCCTCG TGGCTGCTGG GCTGC CATATGTATG

GGAATACTGT ATTTCAGGCA TTATAAGGAA TGAAATTATA GGCCGGGCAT TGTGGCTAAC CCTTGTAATC CTAGCACTTT GAGAGGCTGA AGTGGGCAGA TCACTTGAGC TTCAGAGTTC GAGACCAGCA TGGACAACAT GGTGAAACCC AGTCTCTACC AAAAACACAA AAATATTAGC TGGGTGTGGT GGTGCATGCC TGTAGTCCCA GCTACTCAGG AGGCTGAGGT GGGAGGATCG CTTGAGCCTG GGAGGCAGAA GTTGCAATGA GCAGAGATCG TGCCACTCCG CTCCAGTCTT GGTGACAGAA TGAGACTCCA TCTCAAAAAT AAATAAATAA ATAAATAAAA TAAATGAAAT GAAATTATAA GAAATTACCA CTTTTTCATG TAAGAAGTGA TCATTTCCAT TATAAGGGAA GGAATTTAAT CCTACCTGCC ATTCCACCAA AGCTTACCTA GTGCTAAAGG ATGAGGTGTT AGTAAGACCA ACATCTCAGA GGCCTCTCTG TGCCAATAGC CTTCCTTCCT TTCCCTTCCA AAAACCTCAA

GTGACTAGTT CAGAGGCCTG TCTGGAATAA TGGCATCATC TAATATCACT GGCCTTCTGG AACCTGGGCA TTTTCCAGTG TGTTCCATAC TGTCAATATT CCCCCAGCTT CCTGGACTCC TGTCACAAGC TGGAAAAGTG AGAGGATGGA CAGGGATTAA CCAGAGAGCT CCCTGCTGAG GAAAAAATCT CCCAGATGCT GAAAGTGAGG CCATGTGGCT TGGCCAAATA AAACCTGGCT CCGTGGTGCC TCTGTCTTAG CAGCCACCCT GCTGATGAAC TGCCACCTTG GACTTGGGAC CAGAAAGAGG TGGGTTGGGT GAAGAGGCAC CACACAGAGT GATGTAACAG CAAGATCAGG TCACCCACAG GCCCTGGCAG TCACAGTCAT AAATTAGCTA ACTGTACACA AGCTGGGGAC ACTCCCTTTG GAAACCAAAA AAAAAAAAAA AAAAAAGAGA CCTTTATGCA AAAACAACTC TCTGGATGGC ATGGGGTGAG TATAAATACT TCTTGGCTGC CAGTGTGTTC ATAACTTTGT

AGCGAGTCGA AAACTGAGGC TCCGGCCGCA GAGAACTCAG CCTCATTCCT GCTTTAAAAT CTCTCGGCCA CCTTTGATGA GGGGACTGGG CAGTTCTAGA CAGTCCCGAA GTTCTCAAGG CACAGGTCTC TTCCTGGTTT GACTGTCCTT ACCCCGGGGA GGCAGTGCAG CCAGCTGCAA GGTGAGTTGC C CATATGTATG GGAATACTGT ATTTCAGGCA TTATAAGGAA TGAAATTATA GGCCGGGCAT TGTGGCTAAC CCTTGTAATC CTAGCACTTT GAGAGGCTGA AGTGGGCAGA TCACTTGAGC TTCAGAGTTC GAGACCAGCA TGGACAACAT GGTGAAACCC AGTCTCTACC AAAAACACAA AAATATTAGC TGGGTGTGGT GGTGCATGCC TGTAGTCCCA GCTACTCAGG AGGCTGAGGT GGGAGGATCG CTTGAGCCTG GGAGGCAGAA GTTGCAATGA GCAGAGATCG TGCCACTCCG CTCCAGTCTT GGTGACAGAA TGAGACTCCA TCTCAAAAAT AAATAAATAA

ATAAATAAAA TAAATGAAAT GAAATTATAA GAAATTACCA CTTTTTCATG TAAGAAGTGA TCATTTCCAT TATAAGGGAA GGAATTTAAT CCTACCTGCC ATTCCACCAA AGCTTACCTA GTGCTAAAGG ATGAGGTGTT AGTAAGACCA ACATCTCAGA GGCCTCTCTG TGCCAATAGC CTTCCTTCCT TTCCCTTCCA AAAACCTCAA GTGACTAGTT CAGAGGCCTG TCTGGAATAA TGGCATCATC TAATATCACT GGCCTTCTGG AACCTGGGCA TTTTCCAGTG TGTTCCATAC TGTCAATATT CCCCCAGCTT CCTGGACTCC TGTCACAAGC TGGAAAAGTG AGAGGATGGA CAGGGATTAA CCAGAGAGCT CCCTGCTGAG GAAAAAATCT CCCAGATGCT GAAAGTGAGG CCATGTGGCT TGGCCAAATA AAACCTGGCT CCGTGGTGCC TCTGTCTTAG CAGCCACCCT GCTGATGAAC TGCCACCTTG GACTTGGGAC CAGAAAGAGG TGGGTTGGGT GAAGAGGCAC

CACACAGAGT GATGTAACAG CAAGATCAGG TCACCCACAG GCCCTGGCAG TCACAGTCAT AAATTAGCTA ACTGTACACA AGCTGGGGAC ACTCCCTTTG GAAACCAAAA AAAAAAAAAA AAAAAAGAGA CCTTTATGCA AAAACAACTC TCTGGATGGC ATGGGGTGAG TATAAATACT TCTTGGCTGC CAGTGTGTTC ATAACTTTGT AGCGAGTCGA AAACTGAGGC TCCGGCCGCA GAGAACTCAG CCTCATTCCT GCTTTAAAAT CTCTCGGCCA CCTTTGATGA GGGGACTGGG CAGTTCTAGA CAGTCCCGAA GTTCTCAAGG CACAGGTCTC TTCCTGGTTT GACTGTCCTT ACCCCGGGGA GGCAGTGCAG CCAGCTGCAA GGTGAGTTGC C-3' (FRAG NO J(SEQ ED NO 12385) 5'-CTGCTTTAAA ATCTCTCGGC CACCTTTGAT GAGGGGACTG GGCAGTTCTA GACAGTCCCG AAGTTCTCAA GGCACAGGTC TCTTCCTGGT TTGACTGTCC TTACCCCGGG

GAGGCAGTGC AGCCAGCTGC AAGCCCCACA GTGAAGAACA TCTGAGCTCA AATCCAGATA AGTGACATAA GTGACCTGCT TTGTAAAGCC ATAGAGATGG CCTGTCCTTG GAAATTTCTG TTCAAGACCA AATTCCACCA GTATGCAATG AATGGGGAAA AAGACATCAA CAACAATGTG GAGAAAGCCC CCTGTGCCAC CTCCAGTCCA GTGACACAGG ATGACCTTCA GTATCACAAC CTCAGCAAGC AGCAGAATGA GTCCCCGCAG CCCCTCGTGG AGACGGGAAA GAAGTCTCCA GAATCTCTGG TCAAGCTGGA TGCAACCCCA TTGTCCTCCC CACGGCATGT GAGGATCAAA AACTGGGGCA GCGGGATGAC TTTCCAAGAC ACACTTCACC ATAAGGCCAA AGGGATTTTA ACTTGCAGGT CCAAATCTTG CCTGGGGTCC ATTATGACTC CCAAAAGTTT GACCAGAGGA CCCAGGGACA AGCCTACCCC TCCAGATGAG CTTCTACCTC AAGCTATCGA ATTTGTCAAC CAATATTACG

GCTCCTTCAA AGAGGCAAAA ATAGAGGAAC ATCTGGCCAG GGTGGAAGCG GTAACAAAGG AGATAGAAAC AACAGGAACC TACCAACTGA CGGGAGATGA GCTCATCTTC GCCACCAAGC AGGCCTGGCG CAATGCCCCA CGCTGCATTG GGAGGATCCA GTGGTCCAAC CTGCAGGTCT TCGATGCCCG CAGCTGTTCC ACTGCCCGGG AAATGTTTGA ACACATCTGC AGAGACGTGC GTTACTCCAC CAACAATGGC AACATCAGGT CGGCCATCAC CGTGTTCCCC CAGCGGAGTG ATGGCAAGCA CGACTTCCGG GTGTGGAATG CTCAGCTCAT CCGCTATGCT GGCTACCAGA TGCCAGATGG CAGCATCAGA GGGGACCCTG CCAACGTGGA ATTCACTCAG CTGTGCATCG ACCTGGGCTG GAAGCCCAAG TACGGCCGCT TCGATGTGGT CCCCCTGGTC CTGCAGGCCA ATGGCCGTGA CCCTGAGCTC TTCGAAATCC CACCTGACCT TGTGCTTGAG GTGGCCATGG

AACATCCCAA ATACGAGTGG TTTCGGGAAC TGGAGCTAAA GTGGTACGCC CTGCCTGCAG TGGCCAACAT GCTGCTTGAG GTGGGCGGCC TGGAGTTCCC AGGGTGCCCC TTCAATGGCT GGTACATGGG CACAGAGATC GGAGTCCGGG ACTTCTGTGA CGTCCAGCGC TACAACATCC TGGAGGAAGT GGGCAGGAGA ATGGGCCTGG AAACGCACAA GCTGGCCTCG CTCTGGAAAG ACCAGGCTGT CGTTGAGATC AACATTGCTG TGATCCATAG TTTTCAGAAG CAGAATGTGA CCATCATGGA CCACCACTCG GCTGCAGAAT CCTTCATGAA GTACATGCAG AATGAATACC GGTCCCGTGG GGGCTGCCCG GCAGACTGGA TTTGGCTGGT CCCTCCCATG TCTGGGAGCA TCACCCCCGT GTTTCACCAG GAGATGCTGA ACTACGTCCT GTCCCCTTTC TACTACTATC AGGTAGAGGC CTGGAAAACC CATGTCTGGC AGGACGAGAA GCGGAGACCC AAGAGAAGAG

AGATTCCATT GAAAGTCTTG GTCAAAGCTG TGCTCTTTGC CTGTATGCTG ATGCGCAAGA CAATGGCGTC CCGAGTCAGA GTCACCATCC TCTTTGCGAC AGAGACAGGA AAATCAGAGG CGCTGGCCTG GGACCTGGGG GCCTTATTCA GCTGTGCCTT CAACCCCAAG GTTGTCTGCA TGGATAAGTA CAGGCTGAGC TGCCTGGAGG AGGAACGGCT GCTGTTGGTG GTGACCAGTA CGTTTGGCAA TGGAGACTGC CCTGGCAATG GAGAGAAACT GAAGAAATGG CTCTTCATGC TGAAAGAGCT CAACAACAAA TTCAGGTACG CTGTGTTTGG CCTCGGCTCC AGCATGTACC CTCGGTTCTG CGCCTTTGCT CATGACATTG ATCAGAAGCT GTCCCACCTG GGGGCCTCTC AGCTCACCCC GATGGGAGAA GGGGATGAGC TCAGTGGGCA GGAGGACGCC TTCCGCAGCT GGGCCGTGCA AACCTTCAAG GCAGCCTGTG AGACGTTTGA TGTCCGAGGC AAACAGCACA TTCAGATCCC

CAAGCTCTAC ACCTCCAATG TGACCTGGGA CCCGCACCAC TACAGGCTCG TGCAGGACTC ACAGCCTTTG GACCTCAGCA AAGCCCTCAG CAGCATGCAT GCCAAGAACG TGTTCACCAT GAGGCTCAAA TCTCGGCAGA ATCTACAAAG TCCGACATCC AGCCGTGCCA CCATCCTGGT GGAACTCTCC TGTGAGGATG GCCAAGGCCT GAACTACCTG CCGGGGGAGC ACCTTGGGGT TTGCCCAGGC AACCAGCCGG CCCTGGTCCA AGGCATCCTG GAGCGAGTGG TGGATGGCCC CACACCCCAC CAGACAGTGC GCCTGGAGGA CCTGGATGAG AGTGGCAGCT ACTGGGTCAG TGACAAGAGG CTGCCCCCCT GCTCACTCAG CCAGGCCCTC ACCTACTCCC CGGACATCAC CACACCCCCA ACCCAGCTGC TGCTCCAAAA GCTGGCCCAG GTGGCCACAG AAGAGCCTGA GAGACAGAGG CTGGAGGCCC TGTGCCAGCC CTCAGAGTAC AGCAAGTGGA

AGTTCACCAA CAGCCCCACA TTCCTGGAGG TGCTAGAGGA GTTCCCGTCC CTGCGGGTGT CTGCTGGCTT CCTGCTTTCC CAGCTCCCCA TTCTGAAGCC CAGGTTCTAC TCCATCAGCT CCTCCCGGGA TCACACGCCC ACGGAGATCC ACCTGACTGT GGCCGTGGTC ACCTACCACA CCGGAGATGG CCAGGGTCCC CTGCACCACG GTGTCTGCAG CACATGGCTC AACAGCCTGA AGCCCCAAGA CCCAGTGCCC TGCTTTGTGC GGAATGCCAG CGCCTTCCAC CTCCCCGAGG ATCCCTCCCA TCCTTGCATC CTCATCGGGC CTGGCACAGG CATCGTGCCC TTCCGCAGTT TCTGGCAGCA ACGGCTCCAT GACTCCCAGC ACAAGGGAGT GCGGGGAGGC CGCATGACCT TGGTGTTTGG GTGCCGCCGC CCAGATGAGG ACCACATCTA CCAGGAGGAG ATGCTGGAGA TGGCCCAGAA GGGGGTGCTG CATGCGGTGC ACACAGCCTA TTCCCGCCTG CCTGGCAAGC

CCAAGGTCTA TGTTCAGGAC ATCCTGCGGC AGCAGCTGGC CAGCGAGGTG CTCCGTGTGC TCCACAAGGA GCCAGGCCAC CTCTATGTTT GCGGGGATGT GCGCATGGCC CGGGACGTGG CCCACACCCT GAAGCAGCTG GTGGCTGCCA AGCTGAAATT GAATGAGGAG CAGGTCGAGG ACTATTTCTT TCAGCTCAAG AGCCAGAAGC GCTATCACGA AGATATCTTC GGTGCTGTAT TTCCTTACGA GGCGAAGAAG GACAGGGTGG CGGTGCAGCC CAGCAGCCTG GAGATGTCAG CGCTCTGAGG GCCTACAGGA GGGGTTAAAG CTGCCGGCAC AGAACTTAAG GATGGAGCCA GCTCTGCATT ATCTGAGGTC ACAGGGCCTG GGGAGATGGA GGAAAGTGAT ATCCCCCAGC CTCAAGTCTT ATTTCCTCAA CGTTGCTCCC CATCAAGCCC TTTACTTGAC CTCCTAACAA GTAGCACCCT GGATTGATCG GAGCCTCCTC TCTCAAACTG GGGCCTCCCT GGTCCCTTGG AGACAAAATC TTAAATGCCA GGCCTGGCGA GTGGGTGAAA GATGGAACTT GCTGCTGAGT GCACCACTTC AAGTGACCAC CAGGAGGTGC TATCGCACCA CTGTGTATTT AACTGCCTTG TGTACAGTTA TTTATGCCTC TGTATTTAAA AAACTAACAC CCAGTCTGTT CCCCATGGCC ACTTGGGTCT TCCCTGTATG ATTCCTTGAT GGAGATATTT ACATGAATTG CATTTTACTT TAATC GAATTCCCAC TCTGCTGCCT GCTCCAGCAG ACGGACGCAC AGTAACATGG GCAACTTGAA GAGCGTGGCC CAGGAGCCTG GGCCACCCTG CGGCCTGGGG CTGGGGCTGG GCCTTGGGCT GTGCGGCAAG CAGGGCCCAG CCACCCCGGC CCCTGAGCCC AGCCGGGCCC CAGCATCCCT ACTCCCACCA

GCGCCAGAAC ACAGCCCCCC GAGCTCCCCG CTAACCCAGC CCCCAGAGGG GCCCAAGTTC CCTCGTGTGA AGAACTGGGA GGTGGGGAGC ATCACCTATG ACACCCTCAG CGCCCAGGCG CAGCAGGATG GGCCCTGCAC CCCAAGACGC TGCCTGGGCT CCCTGGTATT TCCACGGAAA CTACAGGGCC GGCCCTCCCC CGGCCCCCCG GCCCCTGAGC AGCTGCTGAG TCAGGCCCGG GACTTCATCA ACCAGTACTA CAGCTCCATT AAGAGGAGCG GCTCCCAGGC CCACGAACAG CGGCTTCAAG AGGTGGAAGG CGAGGTGGCA GCCACAGGCA CCTACCAGCT TAGGGAGAGC GAGCTGGTGT TCGGGGCTAA GCAGGCCTGG CGCAACGCTC CCCGCTGCGT GGGCCGGATC CAGTGGGGGA AGCTGCAGGT GTTCGATGCC CGGGACTGCA GGTCTGCACA GGAAATGTTC ACCTACATCT GCAACCACAT CAAGTATGCC ACCAACCGGG GCAACCTTCG

CTCGGCCATC ACAGTGTTCC CGCAGCGCTG CCCTGGCCGA GGAGACTTCC GAATCTGGAA CAGCCAGCTG GTGCGCTACG CGGGCTACCG GCAGCAGGAC GGCTCTGTGC GGGGGGACCC AGCCAACGTG GAGATCACCG AGCTCTGCAT TCAGCACGGC TGGACCCCAG GAAACGGTCG CTTCGACGTG CTGCCCCTGC TGCTGCAGGC CCCAGATGAG CCCCCAGAAC TCTTCCTTCT GCCCCCCGAG CTGGTCCTTG AGGTGCCCCT GGAGCACCCC ACGCTGGAGT GGTTTGCAGC CCTGGGCCTG CGCTGGTACG CCCTCCCGGC AGTGTCCAAC ATGCTGCTGG AAATTGGGGG CCTGGAGTTC CCCGCAGCCC CCTTCAGTGG CTGGTACATG AGCACTGAGA TCGGCACGAG GAACCTGTGT GACCCTCACC GCTACAACAT CCTGGAGGAT GTGGCTGTCT GCATGGACCT GGATACCCGG ACCACCTCGT CCCTGTGGAA AGACAAGGCA GCAGTGGAAA TCAACGTGGC CGTGCTGCAC

AGTTACCAGC TAGCCAAAGT CACCATCGTG GACCACCACG CCGCCACGGC CTCTTTCATG AAGCACCTGG AGAATGAGCA GAAGGCCAGG GGGGGCTGCC CTGCAGACTG GGCCTGGATC GTGCCCCCCA TCTCGGGCAG CCTCACTCCT GTTTTCCATC AGGAGATGGT CAACTATTTC CTGTCCCCGG CCTTCCGCTA CCAGCCAGAC CCCTGGAAGG GGAGTGCCGC CAAGGGCACC GGCATCACCA GGAAGAAGAC CTTTAAAGAA GTGGCCAACG CCGTGAAGAT CTCCGCCTCG CTCATGGGCA CGGTGATGGC GAAGCGAGTG AAGGCGACAA TCCTGTATGG CTCCGAGACC GGCCGGGCCC AGAGCTACGC ACAGCAGCTG GGGAGACTCT TCCGGAAGGC TTTTGATCCC CGGGTCCTGT GTATGGATGA GTATGACGTG GTGTCCCTCG AACACGAGAC GCTGGTGCTG GTGGTAACCA GCACATTTGG GAATGGGGAT CCCCCGGAGA ATGGAGAGAG CTTTGCAGCT

GCCCTGATGG AGATGTCCGG CCCCTACAAC AGCTCCCCTC GGCCGGAACA GCACAAGAGT TATAAGATCC GCTTCAACAG CATCTCCTGC TCAGACCCAC TGGTGTCCTC TTGGCGGCGG AAGAGGAAGG AGTCCAGTAA CACAGACAGT GCAGGGGCCC TGGGCACCCT CAGGTTCTGT GTGTTCGGGC TCGGCTCCCG GGCATACCCC CACTTCTGCG CCTTTGCTCG TGCCGTGGAC ACACGGCTGG AGGAACTGGG CGGGGAGCGG CTGCTGCAGC TGGGCCAGGG CGACGAGCTG TGCGGCCAGG AGGAGGCCTT CCGAGGCTGG GCCCAGGCTG CCTTCCAGGC CGCCTGTGAG ACCTTCTGTG TGGGAGAGGA TGCCAAGGCC GCCGCCCGAG ACATCTTCAG CCCCAAACGG AGCTGGAAGC GCCAGAGGTA CCGGCTGAGC GCCCAGGCCG AGGGCCTGCA GTTGCTGCCA GGTCTGATCC ACGTGCACAG GCGGAAGATG TTCCAGGCTA CAATCCGCTC AGTGGAAAAC

CTGCAAAGCA GCAAGTCCAC GAGGGCCACC ATCCTGGTGC GCCTGGACAC CGGAGGCCAG GAGGGGCTGC AGTACCAGCC GGGGGACCAC ATAGGTGTCT GCCCGCCCAA CCGGCCCGGC CTTGTGGAGG CGCTGCTGAG CCGCGTGGAG GACCCGCCGG CGCCCACTGA GCCCGTGGCA GTAGAGCAGC TGGAGAAGGG CAGCCCTGGT GGCCCTCCCC CCGGCTGGGT GCGGGACCCC CGGCTGCCCC CGTGCACGCT GCGCCAGGCT CTCACCTTCT TCCTGGACAT CACCTCCCCA CCCAGCCCTC AGCTCTTGCG GCTGCTCAGC ACCTTGGCAG AAGAGCCCAG GGAACAGCAG GAGCTGGAGG CCCTCAGCCA GGATCCCCGA CGCTACGAGG AGTGGAAGTG GTTCCGCTGC CCCACGCTGC TGGAGGTGCT GGAGCAGTTC CCGTCGGTGG CGCTGCCTGC CCCACTGCTC CTCACCCAGC TGCCTCTGCT CCAGCCCCGG TACTACTCAG

TCAGCTCGGC ACCCAGCACC CACCCAGGAG AGATCCACCT CACTGTAGCT GTGCTGGCAT ACAGGACTCA GGATGGGCTG GGCCCCCTGC ACTATGGAGT CTGCTCCACG TGGCTAAGCC AGCTCAAGCC CGGAGACCCT GTGCCCTGCT TCATCCGGGG GGCTCCCTCC TTCCGGCTGC CACCCGATCC CAGCTTGCCC TGCATCCTGG TGGGTCCAGG CACTGGCATT GCCCCCTTCC GGGGATTCTG GCAGGAGCGG CTGCATGACA TTGAGAGCAA AGGGCTGCAG CCCACTCCCA TGACTTTGGT GTTCGGCTGC CGATGCTCCC AACTTGACCA TCTCTACCGC GACGAGGTGC AGAACGCCCA GCAGCGCGGG GTGTTTGGCC GAGTCCTCAC CGCCTTCTCC CGGGAACCTG ACAACCCCAA GACCTACGTG CAGGACATCC TGAGGACGGA GCTGGCTGCG GAGGTGCACC GCGTGCTGTG CCTCGAGCGG GGCCACATGT TTGTCTGCGG CGATGTTACC ATGGCAACCA ACGTCCTGCA

GACCGTGCAG CGCATCCTGG CGACGGAGGG CGACATGGAG CTGGACGAGG CCGGCGACGT CATCGGCGTG CTGCGGGATC AGCAACGCTA CCACGAAGAC ATTTTCGGGC TCACGCTGCG CACCCAGGAG GTGACAAGCC GCATACGCAC CCAGAGCTTT TCCTTGCAGG AGCGTCAGTT GCGGGGCGCA GTGCCCTGGG CGTTCGACCC TCCCGGCTCA GACACCAACA GCCCCTGAGA GCCGCCTGGC TTTCCCTTCC AGTTCCGGGA GAGCGGCTGC CCGACTCAGG TCCGCCCGAC CAGGATCAGC CCCGCTCCTC CCCTCTTGAG GTGGTGCCTT CTCACATCTG TCCAGAGGCT GCAAGGATTC AGCATTATTC CTCCAGGAAG GAGCAAAACG CCTCTTTTCC CTCTCTAGGC CTGTTGCCTC GGGCCTGGGT CCGCCTTAAT CTGGAAGGCC CCTCCCAGCA GCGGTACCCC AGGGCCTACT GCCACCCGCT TCCTGTTTCT TAGTCCGAAT GTTAGATTCC TCTTGCCTCT

CTCAGGAGTA TCTTACCTGT AAAGTCTAAT CTCTAAATCA AGTATTTATT ATTGAAGATT TACCATAAGG GACTGTGCCA GATGTTAGGA GAACTACTAA AGTGCCTACC CCAGCTC-3' (FRAG NO 1897) (SEQ ID NO 12386)

5'-CATATGTATG GGAATACTGT ATTTCAGGCA TTATAAGGAA TGAAATTATA GGCCGGGCAT TGTGGCTAAC CCTTGTAATC CTAGCACTTT GAGAGGCTGA AGTGGGCAGA TCACTTGAGC TTCAGAGTTC GAGACCAGCA TGGACAACAT GGTGAAACCC AGTCTCTACC AAAAACACAA AAATATTAGC TGGGTGTGGT GGTGCATGCC TGTAGTCCCA GCTACTCAGG AGGCTGAGGT GGGAGGATCG CTTGAGCCTG GGAGGCAGAA GTTGCAATGA GCAGAGATCG TGCCACTCCG CTCCAGTCTT GGTGACAGAA

TGAGACTCCA TCTCAAAAAT AAATAAATAA ATAAATAAAA TAAATGAAAT GAAATTATAA GAAATTACCA CTTTTTCATG TAAGAAGTGA TCATTTCCAT TATAAGGGAA GGAATTTAAT CCTACCTGCC ATTCCACCAA AGCTTACCTA GTGCTAAAGG ATGAGGTGTT AGTAAGACCA ACATCTCAGA GGCCTCTCTG TGCCAATAGC CTTCCTTCCT TTCCCTTCCA AAAACCTCAA GTGACTAGTT CAGAGGCCTG TCTGGAATAA TGGCATCATC TAATATCACT GGCCTTCTGG AACCTGGGCA TTTTCCAGTG TGTTCCATAC TGTCAATATT CCCCCAGCTT CCTGGACTCC TGTCACAAGC TGGAAAAGTG AGAGGATGGA CAGGGATTAA CCAGAGAGCT CCCTGCTGAG GAAAAAATCT CCCAGATGCT GAAAGTGAGG CCATGTGGCT TGGCCAAATA AAACCTGGCT CCGTGGTGCC TCTGTCTTAG CAGCCACCCT GCTGATGAAC TGCCACCTTG GACTTGGGAC CAGAAAGAGG

TGGGTTGGGT GAAGAGGCAC CACACAGAGT GATGTAACAG CAAGATCAGG TCACCCACAG GCCCTGGCAG TCACAGTCAT AAATTAGCTA ACTGTACACA AGCTGGGGAC ACTCCCTTTG GAAACCAAAA AAAAAAAAAA AAAAAAGAGA CCTTTATGCA AAAACAACTC TCTGGATGGC ATGGGGTGAG TATAAATACT TCTTGGCTGC CAGTGTGTTC ATAACTTTGT AGCGAGTCGA AAACTGAGGC TCCGGCCGCA GAGAACTCAG CCTCATTCCT GCTTTAAAAT CTCTCGGCCA CCTTTGATGA GGGGACTGGG CAGTTCTAGA CAGTCCCGAA GTTCTCAAGG CACAGGTCTC TTCCTGGTTT GACTGTCCTT ACCCCGGGGA GGCAGTGCAG CCAGCTGCAA GGTGAGTTGC C-3' (FRAG NO J(SEQ ID NO 11875)

5'-CTGCTTTAAA ATCTCTCGGC CACCTTTGAT GAGGGGACTG GGCAGTTCTA GACAGTCCCG AAGTTCTCAA GGCACAGGTC TCTTCCTGGT TTGACTGTCC TTACCCCGGG GAGGCAGTGC AGCCAGCTGC AAGCCCCACA GTGAAGAACA TCTGAGCTCA AATCCAGATA AGTGACATAA GTGACCTGCT TTGTAAAGCC ATAGAGATGG CCTGTCCTTG GAAATTTCTG TTCAAGACCA AATTCCACCA GTATGCAATG AATGGGGAAA AAGACATCAA CAACAATGTG GAGAAAGCCC CCTGTGCCAC CTCCAGTCCA GTGACACAGG ATGACCTTCA GTATCACAAC CTCAGCAAGC AGCAGAATGA GTCCCCGCAG CCCCTCGTGG AGACGGGAAA GAAGTCTCCA GAATCTCTGG TCAAGCTGGA TGCAACCCCA TTGTCCTCCC CACGGCATGT GAGGATCAAA AACTGGGGCA GCGGGATGAC TTTCCAAGAC ACACTTCACC ATAAGGCCAA AGGGATTTTA ACTTGCAGGT CCAAATCTTG

CCTGGGGTCC ATTATGACTC CCAAAAGTTT GACCAGAGGA CCCAGGGACA AGCCTACCCC TCCAGATGAG CTTCTACCTC AAGCTATCGA ATTTGTCAAC CAATATTACG GCTCCTTCAA AGAGGCAAAA ATAGAGGAAC ATCTGGCCAG GGTGGAAGCG GTAACAAAGG AGATAGAAAC AACAGGAACC TACCAACTGA CGGGAGATGA GCTCATCTTC GCCACCAAGC AGGCCTGGCG CAATGCCCCA CGCTGCATTG GGAGGATCCA GTGGTCCAAC CTGCAGGTCT TCGATGCCCG CAGCTGTTCC ACTGCCCGGG AAATGTTTGA ACACATCTGC AGAGACGTGC GTTACTCCAC CAACAATGGC AACATCAGGT CGGCCATCAC CGTGTTCCCC CAGCGGAGTG ATGGCAAGCA CGACTTCCGG GTGTGGAATG CTCAGCTCAT CCGCTATGCT GGCTACCAGA TGCCAGATGG CAGCATCAGA GGGGACCCTG CCAACGTGGA ATTCACTCAG CTGTGCATCG ACCTGGGCTG

GAAGCCCAAG TACGGCCGCT TCGATGTGGT CCCCCTGGTC CTGCAGGCCA ATGGCCGTGA CCCTGAGCTC TTCGAAATCC CACCTGACCT TGTGCTTGAG GTGGCCATGG AACATCCCAA ATACGAGTGG TTTCGGGAAC TGGAGCTAAA GTGGTACGCC CTGCCTGCAG TGGCCAACAT GCTGCTTGAG GTGGGCGGCC TGGAGTTCCC AGGGTGCCCC TTCAATGGCT GGTACATGGG CACAGAGATC GGAGTCCGGG ACTTCTGTGA CGTCCAGCGC TACAACATCC TGGAGGAAGT GGGCAGGAGA ATGGGCCTGG AAACGCACAA GCTGGCCTCG CTCTGGAAAG ACCAGGCTGT CGTTGAGATC AACATTGCTG TGATCCATAG TTTTCAGAAG CAGAATGTGA CCATCATGGA CCACCACTCG GCTGCAGAAT CCTTCATGAA GTACATGCAG AATGAATACC GGTCCCGTGG GGGCTGCCCG GCAGACTGGA TTTGGCTGGT CCCTCCCATG TCTGGGAGCA TCACCCCCGT

GTTTCACCAG GAGATGCTGA ACTACGTCCT GTCCCCTTTC TACTACTATC AGGTAGAGGC CTGGAAAACC CATGTCTGGC AGGACGAGAA GCGGAGACCC AAGAGAAGAG AGATTCCATT GAAAGTCTTG GTCAAAGCTG TGCTCTTTGC CTGTATGCTG ATGCGCAAGA CAATGGCGTC CCGAGTCAGA GTCACCATCC TCTTTGCGAC AGAGACAGGA AAATCAGAGG CGCTGGCCTG GGACCTGGGG GCCTTATTCA GCTGTGCCTT CAACCCCAAG GTTGTCTGCA TGGATAAGTA CAGGCTGAGC TGCCTGGAGG AGGAACGGCT GCTGTTGGTG GTGACCAGTA CGTTTGGCAA TGGAGACTGC CCTGGCAATG GAGAGAAACT GAAGAAATCG CTCTTCATGC TGAAAGAGCT CAACAACAAA TTCAGGTACG CTGTGTTTGG CCTCGGCTCC AGCATGTACC CTCGGTTCTG CGCCTTTGCT CATGACATTG ATCAGAAGCT GTCCCACCTG GGGGCCTCTC AGCTCACCCC GATGGGAGAA

GGGGATGAGC TCAGTGGGCA GGAGGACGCC TTCCGCAGCT GGGCCGTGCA AACCTTCAAG GCAGCCTGTG AGACGTTTGA TGTCCGAGGC AAACAGCACA TTCAGATCCC CAAGCTCTAC ACCTCCAATG TGACCTGGGA CCCGCACCAC TACAGGCTCG TGCAGGACTC ACAGCCTTTG GACCTCAGCA AAGCCCTCAG CAGCATGCAT GCCAAGAACG TGTTCACCAT GAGGCTCAAA TCTCGGCAGA ATCTACAAAG TCCGACATCC AGCCGTGCCA CCATCCTGGT GGAACTCTCC TGTGAGGATG GCCAAGGCCT GAACTACCTG CCGGGGGAGC ACCTTGGGGT TTGCCCAGGC AACCAGCCGG CCCTGGTCCA AGGCATCCTG GAGCGAGTGG TGGATGGCCC CACACCCCAC CAGACAGTGC GCCTGGAGGA CCTGGATGAG AGTGGCAGCT ACTGGGTCAG TGACAAGAGG CTGCCCCCCT GCTCACTCAG CCAGGCCCTC ACCTACTCCC CGGACATCAC CACACCCCCA

ACCCAGCTGC TGCTCCAAAA GCTGGCCCAG GTGGCCACAG AAGAGCCTGA GAGACAGAGG CTGGAGGCCC TGTGCCAGCC CTCAGAGTAC AGCAAGTGGA AGTTCACCAA CAGCCCCACA TTCCTGGAGG TGCTAGAGGA GTTCCCGTCC CTGCGGGTGT CTGCTGGCTT CCTGCTTTCC CAGCTCCCCA TTCTGAAGCC CAGGTTCTAC TCCATCAGCT CCTCCCGGGA TCACACGCCC ACGGAGATCC ACCTGACTGT GGCCGTGGTC ACCTACCACA CCGGAGATGG CCAGGGTCCC CTGCACCACG GTGTCTGCAG CACATGGCTC AACAGCCTGA AGCCCCAAGA CCCAGTGCCC TGCTTTGTGC GGAATGCCAG CGCCTTCCAC CTCCCCGAGG ATCCCTCCCA TCCTTGCATC CTCATCGGGC CTGGCACAGG CATCGTGCCC TTCCGCAGTT TCTGGCAGCA ACGGCTCCAT GACTCCCAGC ACAAGGGAGT GCGGGGAGGC CGCATGACCT TGGTGTTTGG GTGCCGCCGC

CCAGATGAGG ACCACATCTA CCAGGAGGAG ATGCTGGAGA TGGCCCAGAA GGGGGTGCTG CATGCGGTGC ACACAGCCTA TTCCCGCCTG CCTGGCAAGC CCAAGGTCTA TGTTCAGGAC ATCCTGCGGC AGCAGCTGGC CAGCGAGGTG CTCCGTGTGC TCCACAAGGA GCCAGGCCAC CTCTATGTTT GCGGGGATGT GCGCATGGCC CGGGACGTGG CCCACACCCT GAAGCAGCTG GTGGCTGCCA AGCTGAAATT GAATGAGGAG CAGGTCGAGG ACTATTTCTT TCAGCTCAAG AGCCAGAAGC GCTATCACGA AGATATCTTC GGTGCTGTAT TTCCTTACGA GGCGAAGAAG GACAGGGTGG CGGTGCAGCC CAGCAGCCTG GAGATGTCAG CGCTCTGAGG GCCTACAGGA GGGGTTAAAG CTGCCGGCAC AGAACTTAAG GATGGAGCCA GCTCTGCATT ATCTGAGGTC ACAGGGCCTG GGGAGATGGA GGAAAGTGAT ATCCCCCAGC CTCAAGTCTT

ATTTCCTCAA CGTTGCTCCC CATCAAGCCC TTTACTTGAC CTCCTAACAA GTAGCACCCT GGATTGATCG GAGCCTCCTC TCTCAAACTG GGGCCTCCCT GGTCCCTTGG AGACAAAATC TTAAATGCCA GGCCTGGCGA GTGGGTGAAA GATGGAACTT GCTGCTGAGT GCACCACTTC AAGTGACCAC CAGGAGGTGC TATCGCACCA CTGTGTATTT AACTGCCTTG TGTACAGTTA TTTATGCCTC TGTATTTAAA AAACTAACAC CCAGTCTGTT CCCCATGGCC ACTTGGGTCT TCCCTGTATG ATTCCTTGAT GGAGATATTT ACATGAATTG CATTTTACTT TAATC-3' (FRAG NO J(SEQ IDNO 11876) 5'-GAATTCCCAC TCTGCTGCCT GCTCCAGCAG ACGGACGCAC AGTAACATGG GCAACTTGAA GAGCGTGGCC CAGGAGCCTG GGCCACCCTG CGGCCTGGGG

CTGGGGCTGG GCCTTGGGCT GTGCGGCAAG CAGGGCCCAG CCACCCCGGC CCCTGAGCCC AGCCGGGCCC CAGCATCCCT ACTCCCACCA GCGCCAGAAC ACAGCCCCCC GAGCTCCCCG CTAACCCAGC CCCCAGAGGG GCCCAAGTTC CCTCGTGTGA AGAACTGGGA GGTGGGGAGC ATCACCTATG ACACCCTCAG CGCCCAGGCG CAGCAGGATG GGCCCTGCAC CCCAAGACGC TGCCTGGGCT CCCTGGTATT TCCACGGAAA CTACAGGGCC GGCCCTCCCC CGGCCCCCCG GCCCCTGAGC AGCTGCTGAG TCAGGCCCGG GACTTCATCA ACCAGTACTA CAGCTCCATT AAGAGGAGCG GCTCCCAGGC CCACGAACAG CGGCTTCAAG AGGTGGAAGC CGAGGTGGCA GCCACAGGCA CCTACCAGCT TAGGGAGAGC GAGCTGGTGT TCGGGGCTAA GCAGGCCTGG CGCAACGCTC CCCGCTGCGT GGGCCGGATG CAGTGGGGGA AGCTGCAGGT GTTCGATGCC CGGGACTGCA GGTCTGCACA GGAAATGTTC ACCTACATCT GGAACCACAT CAAGTATGCC ACCAACCGGG GCAACCTTCG CTCGGCCATC ACAGTGTTCC CGCAGCGCTG CCCTGGCCGA GGAGACTTCC GAATCTGGAA CAGCCAGCTG GTGCGCTACG CGGGCTACCG GCAGCAGGAC GGCTCTGTGC GGGGGGACCC AGCCAACGTG GAGATCACCG AGCTCTGCAT TCAGCACGGC TGGACCCCAG GAAACGGTCG CTTCGACGTG CTGCCCCTGC TGCTGCAGGC CCCAGATGAG CCCCCAGAAC TCTTCCTTCT GCCCCCCGAG CTGGTCCTTG AGGTGCCCCT GGAGCACCCC ACGCTGGAGT GGTTTGCAGC CCTGGGCCTG CGCTGGTACG CCCTCCCGGC AGTGTCCAAC ATGCTGCTGG

AAATTGGGGG CCTGGAGTTC CCCGCAGCCC CCTTCAGTGG CTGGTACATG AGCACTGAGA TCGGCACGAG GAACCTGTGT GACCCTCACC GCTACAACAT CCTGGAGGAT GTGGCTGTCT GCATGGACCT GGATACCCGG ACCACCTCGT CCCTGTGGAA AGACAAGGCA GCAGTGGAAA TCAACGTGGC CGTGCTGCAC AGTTACCAGC TAGCCAAAGT CACCATCGTG GACCACCACG CCGCCACGGC CTCTTTCATG AAGCACCTGG AGAATGAGCA GAAGGCCAGG GGGGGCTGCC CTGCAGACTG GGCCTGGATC GTGCCCCCCA TCTCGGGCAG CCTCACTCCT GTTTTCCATC AGGAGATGGT CAACTATTTC CTGTCCCCGG CCTTCCGCTA CCAGCCAGAC GCCTGGAAGG GGAGTGCCGC CAAGGGCACC GGCATCACCA GGAAGAAGAC CTTTAAAGAA GTGGCCAACG CCGTGAAGAT CTCCGCCTCG CTCATGGGCA CGGTGATGGC GAAGCGAGTG AAGGCGACAA

TCCTGTATGG CTCCGAGACC GGCCGGGCCC AGAGCTACGC ACAGCAGCTG GGGAGACTCT TCCGGAAGGC TTTTGATCCC CGGGTCCTGT GTATGGATGA GTATGACGTG GTGTCCCTCG AACACGAGAC GCTGGTGCTG GTGGTAACCA GCACATTTGG GAATGGGGAT CCCCCGGAGA ATGGAGAGAG CTTTGCAGCT GCCCTGATGG AGATGTCCGG CCCCTACAAC AGCTCCCCTC GGCCGGAACA GCACAAGAGT TATAAGATCC GCTTCAACAG CATCTCCTGC TCAGACCCAC TGGTGTCCTC TTGGCGGCGG AAGAGGAAGG AGTCCAGTAA CACAGACAGT GCAGGGGCCC TGGGCACCCT CAGGTTCTGT GTGTTCGGGC TCGGCTCCCG GGCATACCCC CACTTCTGCG CCTTTGCTCG TGCCGTGGAC ACACGGCTGG AGGAACTGGG CGGGGAGCGG CTGCTGCAGC TGGGCCAGGG CGACGAGCTG TGCGGCCAGG AGGAGGCCTT CCGAGGCTGG GCCCAGGCTG

CCTTCCAGGC CGCCTGTGAG ACCTTCTGTG TGGGAGAGGA TGCCAAGGCC GCCGCCCGAG ACATCTTCAG CCCCAAACGG AGCTGGAAGC GCCAGAGGTA CCGGCTGAGC GCCCAGGCCG AGGGCCTGCA GTTGCTGCCA GGTCTGATCC ACGTGCACAG GCGGAAGATG TTCCAGGCTA CAATCCGCTC AGTGGAAAAC CTGCAAAGCA GCAAGTCCAC GAGGGCCACC ATCCTGGTGC GCCTGGACAC CGGAGGCCAG GAGGGGCTGC AGTACCAGCC GGGGGACCAC ATAGGTGTCT GCCCGCCCAA CCGGCCCGGC CTTGTGGAGG CGCTGCTGAG CCGCGTGGAG GACCCGCCGG CGCCCACTGA GCCCGTGGCA GTAGAGCAGC TGGAGAAGGG CAGCCCTGGT GGCCCTCCCC CCGGCTGGGT GCGGGACCCC CGGCTGCCCC CGTGCACGCT GCGCCAGGCT CTCACCTTCT TCCTGGACAT CACCTCCCCA CCGAGCCCTC AGCTCTTGCG GCTGCTCAGC

ACCTTGGCAG AAGAGCCCAG GGAACAGCAG GAGCTGGAGG CCCTCAGCCA GGATCCCCGA CGCTACGAGG AGTGGAAGTG GTTCCGCTGC CCCACGCTGC TGGAGGTGCT GGAGCAGTTC CCGTCGGTGG CGCTGCCTGC CCCACTGCTC CTCACCCAGC TGCCTCTGCT CCAGCCCCGG TACTACTCAG TCAGCTCGGC ACCCAGCACC CACCCAGGAG AGATCCACCT CACTGTAGCT GTGCTGGGAT ACAGGACTCA GGATGGGCTG GGCCCCCTGC ACTATGGAGT CTGCTCCACG TGGCTAAGCC AGCTCAAGCC CGGAGACCCT GTGCCCTGCT TCATCCGGGG GGCTCCCTCC TTCCGGCTGC CACCCGATCC CAGCTTGCCC TGCATCCTGG TGGGTCCAGG CACTGGCATT GCCCCCTTCC GGGGATTCTG GCAGGAGCGG CTGCATGACA TTGAGAGCAA AGGGCTGCAG CCCACTCCCA TGACTTTGGT GTTCGGCTGC CGATGCTCCC AACTTGACCA TCTCTACCGC

GACGAGGTGC AGAACGCCCA GCAGCGCGGG GTGTTTGGCC GAGTCCTCAC CGCCTTCTCC CGGGAACCTG ACAACCCCAA GACCTACGTG CAGGACATCC TGAGGACGGA GCTGGCTGCG GAGGTGCACC GCGTGCTGTG CCTCGAGCGG GGCCACATGT TTGTCTGCGG CGATGTTACC ATGGCAACCA ACGTCCTGCA GACCGTGCAG CGCATCCTGG CGACGGAGGG CGACATGGAG CTGGACGAGG CCGGCGACGT CATCGGCGTG CTGCGGGATC AGCAACGCTA CCACGAAGAC ATTTTCGGGC TCACGCTGCG CACCCAGGAG GTGACAAGCC GCATACGCAC CCAGAGCTTT TCCTTGCAGG AGCGTCAGTT GCGGGGCGCA GTGCCCTGGG CGTTCGACCC TCCCGGCTCA GACACCAACA GCCCCTGAGA GCCGCCTGGC TTTCCCTTCC AGTTCCGGGA GAGCGGCTGC CCGACTCAGG TCCGCCCGAC CAGGATCAGC CCCGCTCCTC CCCTCTTGAG GTGGTGCCTT

CTCACATCTG TCCAGAGGCT GCAAGGATTC AGCATTATTC CTCCAGGAAG GAGCAAAACG CCTCTTTTCC CTCTCTAGGC CTGTTGCCTC GGGCCTGGGT CCGCCTTAAT CTGGAAGGCC CCTCCCAGCA GCGGTACCCC AGGGCCTACT GCCACCCGCT TCCTGTTTCT TAGTCCGAAT GTTAGATTCC TCTTGCCTCT CTCAGGAGTA TCTTACCTGT AAAGTCTAAT CTCTAAATCA AGTATTTATT ATTGAAGATT TACCATAAGG GACTGTGCCA GATGTTAGGA GAACTACTAA AGTGCCTACC CCAGCTC-3' (FRAG NO J(SEQ DD NO 11877) 5'-CCCCGGGG-3' (FRAG NO 1898) (SEQ NO 11280)

5'-GGGGCCGCTGGG-3' (FRAG NO 1899) (SEQ ID NO 11281) 5'-GGGGGTGTGG-3' (FRAG NO 1900) (SEQ ID NO 11282) 5'-CTGCCTCCCCGGGGT-3' (FRAG NO 1442)(SEQ ID NO 10820) 5'-TTCTGCTGCTTGCTG-3' (FRAG NO 1443)(SEQ ID NO 10821) 5'-CTTCTTTCCCGTCTCC-3' (FRAG NO 1444)(SEQ ID NO 10822)

5'-CTTCTTTCCCGTCTCC-3' (FRAG NO 1445)(SEQ DD NO 10823) 5'-TTTTTGCCTCTTTG-3' (FRAG NO 1446)(SEQ DD NO 10824) 5'-GGTTCCTGTTGTTrCT-3' (FRAG NO 1447) (SEQ ID NO 10825) 5'-GGCCTGCTTGGTGGCG-3' (FRAG NO 1448)(SEQ ID NO 10826) 5'-GCTTGTGCGTTTCC-3' (FRAG NO 1449)(SEQ ID NO 10827)

5'-TCTCTCTTCTCTTGGGTCTCCGCTTCTCGTCCTGCC-3' (FRAG NO 1450)(SEQ ID NO 10828) 5'-TTTTCCTGTCTCTGTCGC-3' (FRAG NO 1451)(SEQ ID NO 10829) 5'-GCCGTTCCTCCTCC-3' (FRAG NO 1452)(SEQ ID NO 10830) 5'-GGCGTCCTCCTGCCC-3' (FRAG NO 1453)(SEQ ID NO 10831) 5'-TGTGCTGTTTGCCTCGG-3' (FRAG NO 1454)(SEQ ED NO 10832)

5'-GTGGTGCGGGTCCC-3' (FRAG NO 1455)(SEQ ID NO 10833) 5' GGTGCTCCCCCGGC-3' (FRAG NO 1456)(SEQ ID NO 10834) 5'-GGGCCGGCTGGTTGCCTGGGC-3' (FRAG NO 1457)(SEQ DDNO 10835) 5'-CTGTCTGGTGGGGTGTGGGGCC-3' (FRAG NO 1458)(SEQ ID NO 10836) 5'-GCTGGGTTGGGGGTGTGGTG-3' (FRAG NO 1459)(SEQ ID NO 10837)

5'-GGCTCTTCTGTGGCC-3' (FRAG NO 1460)(SEQ ID NO 10838) 5'-TGTGGGGCTGTTGGTG-3' (FRAG NO 1461)(SEQ ID NO 10839) 5'-TCTCTGTGGGCGTGTG-3' (FRAG NO 1462)(SEQ ID NO 10840) 5'-CTGGGTCTTGGGGCTTC-3' (FRAG NO 1463)(SEQ ID NO 10841) 5'-CTCCCTTGTGCTGGG-3' (FRAG NO 1464)(SEQ ID NO 10842)

5'-TGCGGCCTCCCCGC-3' (FRAG NO 1465)(SEQ ID NO 10843) 5'-CCCCCTTCTGGGCC-3' (FRAG NO 1466)(SEQ ID NO 10844) 5'-GGTGGCCTGGCTCCTTGTGG-3' (FRAG NO 1467)(SEQ ID O 10845) 5'-GCGCTTCTGGCTCTTG-3' (FRAG NO 1468)(SEQ ID NO 10846) 5'-CCCTGTCCTTCTTCGCCTCGT-3' (FRAG NO 1469)(SEQ ID NO 10847)

5'-GGCTGCTGGGCTGC-3' (FRAG NO 1470)(SEQ DD NO 10848) 5'-CTGCCCCBGTTTTTGBTCCTCBCBTGCCGTGGGGBGGBCBBTGG-3'(FRAG NO 1901) (SEQ DD NO 11283)

NF-κB Nucleic Acids and Antisense Oligonucleotide Fragments

5'-CGGCCCTTCT CACTGGAGGC ACCGGGCAGT CCTCCATGGG AGGGTTGGGC TTGGCCGGGG CTGCCCGGTG CCTCCTCTTG GCTGGTCCCT CGTTGTCCTT GGGCCCCGC TCCCGCTGCT CGGCCTCCGT GTTCTTTGGC CTCTTGCTCC GCCTGCTGTC TTGTCCCGTC CCCTCCTCGC TTGCGTTTCC CTCTTCCTTG TCTTCCAGGC CTTCCTCCGC

TTCCGCTGCT GGGGCCCGCG CCGGGGGGGC GCTCGGCTCC GCGGCTTCCT CCCCGGCTGG GGGGTCCTGG TCTCCGGGGC CTGCGGCTCG CGGGCTCGGG GCTGCGTGCG

CCGCGCGCGG CGTCCGCGGT GGGTGGCGCT GTCCCGCCGT GGTGTGTCTC CGTTCTCGTC CTGCGCCGTC CTGGTCTGCC CGTGGGGTCC TGGGCGTGGT GGGGGGCGTC

TGGTGCCTCG TCTGCCCCGT GGGGCTTCGG GCTCGGGGCT GTTCGTCCCC CCTGCCGCTC TGTGGCCTCC GGGGCTCCTC GTTTTCGCTG CTTCGGGTGT CCTTCTCGGC

GTGTGGCCCC GGGTCCCGGC CCTGCTGGGC TGGGCGGGGT CGCTGCCCTG GGCTTCTGGC CCGTCTGGTT GTCTGTCGGT GCTTGTCTCG GGTTTCTGGC CTCTGTGCTG GGCGCTTCTC TGCCTCCTGC TCCGCCCTCC TGGTGGCTCG GCTGGGGGTG CCCGTGCGGG GGTGGGTGTG GGGTGTTTTC GGGGTCCTCC CCTTCCC-3' (FRAG NO 1902)

(SEQ ED NO 11284)

5'-GGGCGGGGTCGC-3' (FRAG NO 1903) (SEQ ID NO 11285)

5'-GCGCCGTCC-3' (FRAG NO 1904) (SEQ DD NO 11286)

5'-GGGCGTGGTGG-3' (FRAG NO 1905) (SEQ ID NO 11287) 5'-GTTGGGCTTGGCCGGGG-3' (FRAG NO 1471)(SEQ ID NO 10849)

5'-CTGCCCGGTGCCTCC-3' (FRAG NO 1472)(SEQ ED NO 10850)

5'-TCTTGGCTGGTCCCTCGT-3' (FRAG NO 1473)(SEQ ID NO 10851)

5'-TGTCCTTGGGCCCC-3' (FRAG NO 1474)(SEQ ID NO 10852)

5'-GCTCCCGCTGCTCGGCCTCCGT-3' (FRAG NO 1475)(SEQ ID NO 10853) 5'-GTTCTTTGGCCTCTTGCTCC-3' (FRAG NO 1476)(SEQ ID NO 10854)

5'-GCCTGCTGTCTTGTCC-3' (FRAG NO 1477)(SEQ DD NO 10855)

5'-CGTCCCCTCCTCGCTTGCGTTTC-3' (FRAG NO 1478)(SEQ ID NO 10856)

5'-CCTCTTCCTTGTCTTCCA-3' (FRAG NO 1479)(SEQ ID NO 10857)

5'-GGCCTTCCTCCGCTTCCGCTGC-3' (FRAG NO 1480)(SEQ ID NO 10858) 5'-TGGGGCCCGCGCCGG-3' (FRAG NO 1481)(SEQ ID NO 10859)

5'-GGGGGCGCTCGGCTCCGCGGCTTCCTCCCCGG-3' (FRAG NO 1482)(SEQ ID NO 10860)

5'-CTGGGGGGTCCTGG-3" (FRAG NO 1483)(SEQ IDNO 10861)

5'-TCTCCGGGGCCTGCGGCTCGC-3' (FRAG NO 1484)(SEQ ID NO 10862)

5'-GGGCTCGOGGCTGCGTGCGCC-3' (FRAG NO 1485)(SEQ ID NO 10S63) 5'-GCGCGCGGCGTCCGCGGTG-3' (FRAG NO 1486)(SEQ DD NO 10864)

5'-GGTGGCGCTGTCCCGCC-3' (FRAG NO 1487)(SEQ ED NO 10865)

5'-GTGGTGTGTCTCCGTTCTCGTCCTGCGCCGTC-3' (FRAG NO 1488)(SEQ LD NO 10866)

5'-CTGGTCTGCCCGTGG-3' (FRAG NO 1489)(SEQ DD NO 10867)

5'-GGTCCTGGGCGTGGTGG-3' (FRAG NO 1490)(SEQ DD NO 10868) 5'-GGGGCGTCTGGTGC-3' (FRAG NO 1491)(SEQ ID NO 10869)

5'-CTCGTCTGCCCCGTG-3' (FRAG NO 1492)(SEQ DD NO 10870)

5'-GGGCTTCGGGCTCGG-3' (FRAG NO 1493) (SEQ ED NO 10871)

5'-GGCTGTTCGTCCCCCCTGCCGCTCTGTGGCCTCC-3' (FRAG NO 1494)(SEQ DD NO 10872) 5'-GGGGCTCCTCGTTTTC-3' (FRAG NO 1495)(SEQ DD NO 10873)

S'-GCTGCTTCGGGTGTCCTTCTCJ' (FRAG NO 1496)(SEQ DD NO 10874)

5'-GGCGTGTGGCCCCGG-3' (FRAG NO 1497)(SEQ DD NO 10875)

5'-GTCCCGGCCCTGCTGGGCTGGGCGGGGTC-3' (FRAG NO 1498)(SEQ DDNO 10876)

5'-GCTGCCCTGGGCTTCTGGCCCGTCT-3' (FRAG NO 1499)(SEQ DD NO 10877) 5'-GGTTGTCTGTCGGT-3' (FRAG NO 1500)(SEQ ID NO 10878)

5'-GCTTGTCTCGGGTTTCTGG 3' (FRAG NO 1501)(SEQ ID O 10879)

5'-CCTCTGTGCTGGGC-3' (FRAG NO 1502)(SEQ D NO 10880)

5'-GCTTCTCTGCCTCCTGCTCC-3' (FRAG NO 1503)(SEQ ID O 10881)

5'-GCCCTCCTGGTGGCTC-3' (FRAG NO 1504)(SEQ ID NO 10882) 5'-GGCTGGGGGTGCCCGTGCG-3' (FRAG NO 1505)(SEQ DD NO 10883)

5'-GGGGTGGGTGTGGGGTGTT-3' (FRAG NO 1S06)(SEQ DD O 10884)

5'-TTCGGGGTCCTCCCCTTCCC-3' (FRAG NO 1507)(SEQ DD NO 10885)

5'-CGGCCCTTCTCACTGGAGGCACCGGGCAGTCCTCCATGGGAGG-3' (FRAGNO 1906)(SEQ DD O 11288)

Human Major Basic Protein Nucleic Acids and Antisense Oligonucleotide Fragments 5'-GTT TCA TCT TGG CTT TAT CCTCT CCC CTT GTT CCT CCC CTCT CCT GCT CTG GRG TCT CCT C TTC CCT CCC TCC CCT GCC GTG TTG TCT GTG GGT GTC GTT TCG

CTC TTG TTG CCC TGG GCC CTT CCC TGC TGG GGG GGA GTT TCA TCT TGG GTT TCB TCT TGG CTT TBT CCTCT CCC CTT GTT CCT CCC CTCT CCT GCT CTG GRG

TCT CCT C TTC CCT CCC TCC CCT GCC GTG TTG TCT GTG GGT GTC GTT TCG CTC TTG TTG CCC TGG GCC CTT CCC TGC TGG GGG GGB GTT TCB TCT TGG-3'

(FRAG ID 1 07) (SEQ ID NO 11289)

5'-GGG GGA GTT-3' (FRAG ID 1908) (SEQ ID NO 11290) 5'-G CCC TGG GCC C-3' (FRAG ID 1909) (SEQ ID NO 11291)

5'-GTT TCA TCT TGG CTT TAT CC-3' (FRAG NO 1508) (SEQ ID NO 10886)

5'-TCT CCC CTT GTT CCT CCC C-3' (FRAG NO 1509)(SEQ ID NO 10887)

5'-TCT CCT GCT CTG GRG TCT CCT C-3' (FRAG NO 1510)(SEQ ID NO 10888)

5'-TTC CCT CCC TCC CCT GCC-3' (FRAG NO 1511)(SEQ ID NO 10889) 5'-GTG TTG TCT GTG GGT GTC C-3' (FRAG NO I512)(SEQ ID NO 10890)

5'-GTT TCG CTC TTG TTG CCC-3' (FRAG NO 1513)(SEQ ID NO 10891)

5'-TGG GCC CTT CCC TGC TGG-3' (FRAG NO 1514)(SEQ DD NO 10892)

5--GGG GGA GTT TCA TCT TGG-3' (FRAG NO 1515)(SEQ DDNO 10893)

5'-GTT TCA TCT TGG CTT TAT CCTCT CCC CTT GTT CCT CCC CTCT CCT GCT CTG GRG TCT CCT C TTC CCT CCC TCC CCT GCC GTG TTG TCT GTG GGT GTC GTT TCG CTC TTG TTG CCC TGG GCC CTT CCC TGC TGG GGG GGA GTT TCA TCT TGG-3' (FRAG DD 1910) (SEQ DD O 11292)

5'-GTT TCB TCT TGG CTT TBT CCTCT CCC CTT GTT CCT CCC CTCT CCT GCT CTG GRG TCT CCT C TTC CCT CCC TCC CCT GCC GTG TTG TCT GTG GGT GTC GTT TCG

CTC TTG TTG CCC TGG GCC CTT CCC TGC TGG GGG GGB GTT TCB TCT TGG-3' (FRAG ID 1911) (SEQ ID NO 11293)

Human Eosinophil Major Basic Protein Nucleic Acids and Antisense Oligonucleotide Fragments

5'-GGG GGB GTT TCB TCT TGG CTT T-3' (FRAG NO 1516)(SEQ ID O 10894) 5'-GGG GGB GTT TCB TCT TGG CTT-3' (FRAG NO 1517)(SEQ ID NO 10895)

5'-GGG GGB GTT TCB TCT TGG CT-3' (FRAG NO 1518)(SEQ ED NO 10896)

5'-GGG GGB GTT TCB TCT TGG C-3' (FRAG NO 1519)(SEQ ID NO 10897)

5'-GGG GGB GTT TCB TCT TGG-3' (FRAG NO 1520)(SEQ ID NO 10898)

5'-GGG GGB GTT TCB TCT TG-3' (FRAG NO 1521)(SEQ ID NO 10899) 5'-GGG GGB GTT TCB TCT T-3' (FRAG NO 1522)(SEQ DD NO 10900)

5'-GGG GGB GTT TCB TCT-3' (FRAG NO 1523)(SEQ E O 10901)

5'-GGG GGB GTT TCB TC-3' (FRAG NO 1524)(SEQ DD NO 10902)

5'-GGG GGB GTT TCB T-3' (FRAG NO 1525)(SEQ DD NO 10903)

5'-GGG GGB GTT TCB 3' (FRAG NO 1526)(SEQ ID NO 10904) 5'-GG GGB GTT TCB TCT TGG CTT T-3' (FRAG NO 1527)(SEQ ID NO 10905)

S'-GG GGB GTT TCB TCT TGG CTT-3' (FRAG NO 1528)(SEQ ID NO 10906)

5'-GG GGB GTT TCB TCT TGG CT-3' (FRAG NO 1529)(SEQ DD NO 10907)

5'-GG GGB GTT TCB TCT TGG C-3' (FRAG NO 1530)(SEQ ID NO 10908)

S'-GG GGB GTT TCB TCT TGG-3' (FRAG NO 1531)(SEQ ID NO 10909) 5'-GG GGB GTT TCB TCT TG 3' (FRAG NO 1532)(SEQ ID NO 10910) y-GG GGB GTT TCB TCT T-3' (FRAG NO 1533)(SEQ DDNO 10911)

S'-GG GGB GTT TCB TCT-3' (FRAG NO 1534)(SEQ ID NO 10912)

S'-GG GGB GTT TCB TC-3' (FRAG NO 1535)(SEQ ID NO 10913)

S'-GG GGB GTT TCB T-3' (FRAG NO 1536)(SEQ ID NO 10914) 5'-G GGB GTT TCB TCT TGG CTT T-3' (FRAG NO 1537)(SEQ ID NO 10915)

5'-G GGB GTT TCB TCT TGG CTT-3' (FRAG NO 1538)(SEQ ID NO 10916)

5'-G GGB GTT TCB TCT TGG CT-3' (FRAG NO 1539)(SEQ DD NO 10917)

S'-G GGB GTT TCB TCT TGG C-3' (FRAG NO 1540)(SEQ ID NO 10918)

5'-G GGB GTT TCB TCT TGG-3' (FRAG NO 1541)(SEQ ID NO 10919) 5'-G GGB GTT TCB TCT TG-3' (FRAG NO 1542)(SEQ ID NO 10920)

S'-G GGB GTT TCB TCT T-3' (FRAG NO 1543)(SEQ DD NO 10921)

S'-G GGB GTT TCB TCT-3' (FRAG NO 1544)(SEQ ID NO 10922)

S'-G GGB GTT TCB TC-3' (FRAG NO 1545)(SEQ ID NO 10923)

5'-GGB GTT TCB TCT TGG CTT T-3' (FRAG NO 1546)(SEQ π NO 10924) 5'-GGB GTT TCB TCT TGG CTT-3' (FRAG NO 1547)(SEQ ID NO 10925)

5'-GGB GTT TCB TCT TGG CT-3' (FRAG NO 1548)(SEQ ID NO 10926)

S'-GGB GTT TCB TCT TGG C-3' (FRAG NO 1549)(SEQ DD NO 10927)

5'-GGB GTT TCB TCT TGG-3' (FRAG NO 1550)(SEQ DD NO 10928)

5'-GGB GTT TCB TCT TG-3' (FRAG NO 1551)(SEQ DD NO 10929) 5'-GGB GTT TCB TCT T-3' (FRAG NO 1552)(SEQ ID NO 10930)

5'-GGB GTT TCB TCT-3' (FRAG NO 1553)(SEQ ID NO 10931)

5'-GB GTT TCB TCT TGG CTT T-3' (FRAG NO 1554)(SEQ ID NO 10932)

5'-GB GTT TCB TCT TGG CTT-3' (FRAG NO 1555)(SEQ ID NO 10933)

5'-GB GTT TCB TCT TGG CT-3' (FRAG NO 1556)(SEQ ED NO 10934) 5'-GB GTT TCB TCT TGG C-3' (FRAG NO 1557)(SEQ ID NO 10935)

5'-GB GTT TCB TCT TGG-3' (FRAG NO 1558)(SEQ DD NO 10936)

5'-GB GTT TCB TCT TG-3' (FRAG NO 1559)(SEQ D NO 10937)

S'-GB GTT TCB TCT T-3' (FRAG NO 1560)(SEQ ID NO 10938)

5'-B GTT TCB TCT TGG CTT T-3' (FRAG NO 1561)(SEQ DD NO 10939) 5'-B GTT TCB TCT TGG CTT-3' (FRAG NO 1562)(SEQ ID NO 10940)

5'-B GTT TCB TCT TGG CTT-3' (FRAG NO 1563)(SEQ DD NO 10941)

5'-B GTT TCB TCT TGG CT-3' (FRAG NO 1564)(SEQ ID NO 10942)

5'-B GTT TCB TCT TGG C-3' (FRAG NO 1565)(SEQ DD NO 10943)

S'-B GTT TCB TCT TGG-3' (FRAG NO 1565)(SEQ DD NO 10944) 5'-B GTT TCB TCT TG-3' (FRAG NO 1567)(SEQ ID NO 10945)

5'-GTT TCB TCT TGG CTT T-3' (FRAG NO 1568)(SEQ DD NO 10946)

5'-GTT TCB TCT TGG CTT-3' (FRAG NO 1569)(SEQ ID NO 10947)

5'-GTT TCB TCT TGG CT-3' (FRAG NO 1570)(SEQ DDNO 10948)

5'-GTT CB TCT TGG C-3' (FRAG NO 1571)(SEQ ID NO 10949) 5'-GTT TCB TCT TGG-3' (FRAG NO 1572)(SEQ ID NO 10950)

5'-TT TCB TCT TGG CTT T-3' (FRAG NO 1573)(SEQ ID NO 10951)

5'-TT TCB TCT TGG CTT-3' (FRAG NO 1574)(SEQ ID NO 10952)

5'-TT TCB TCT TGG CT-3' (FRAG NO 1575)(SEQ ID NO 10953)

5'-TT TCB TCT TGG C-3' (FRAG NO 1576)(SEQ ID NO 10954) 5'-T TCB TCT TGG CTT T-3' (FRAG NO 1577)(SEQ ED O 10955)

5'-T TCB TCT TGG CTT-3' (FRAG NO 1578)(SEQ ID NO 10956)

5'-T TCB TCT TGG CT-3' (FRAG NO 1579)(SEQ DD NO 10957)

5'-TCB TCT TGG CTT T-3' (FRAG NO 1580)(SEQ DD NO 10958) 5'-TCB TCT TGG CTT-3' (FRAG NO 1581)(SEQ ED NO 10959)

5' GGG GGB GTT TCB TCT TGG CTT T-3' (FRAG NO 1582)(SEQ ID NO 10960)

5'-GG GGB GTT TCB TCT TGG CTT T-3' (FRAG NO 1583)(SEQ DD NO 10961)

5'-G GGB GTT TCB TCT TGG CTT T-3' (FRAG NO 1584)(SEQ ID NO 10962)

5'-GGB GTT TCB TCT TGG CTT T-3' (FRAG NO 1585)(SEQ ED NO 10963) 5'-GB GTT TCB TCT TGG CTT T-3' (FRAG NO 1586)(SEQ ID NO 10964)

5'-B GTT TCB TCT TGG CTT T-3' (FRAG NO 1587)(SEQ ED NO 10965)

5'-GTT TCB TCT TGG CTT T-3' (FRAG NO 1588)(SEQ ED NO 10966)

5'-TT TCB TCT TGG CTT T-3' (FRAG NO 1S89)(SEQ ID NO 10967)

5'-T TCB TCT TGG CTT T-3' (FRAG NO 1590)(SEQ ID NO 10968) 5'-TCB TCT TGG CTT T-3' (FRAG NO 1591)(SEQ DD NO 10969)

5'-CB TCT TGG CTT T-3' (FRAG NO 1592)(SEQ DDNO 10970)

5' GGG GGB GTT TCB TCT TGG CTT-3' (FRAG NO 1593)(SEQ DD NO 10971)

5'-GG GGB GTT TCB TCT TGG CTT-3' (FRAG NO 1594)(SEQ ID O 10972)

5'-G GGB GTT TCB TCT TGG CTT-3' (FRAG NO 1595)(SEQ DDNO 10973) 5'-GGB GTT TCB TCT TGG CTT-3' (FRAG NO 1596)(SEQ ID NO 10974)

5'-GB GTT TCB TCT TGG CTT-3' (FRAG NO 1597)(SEQ ID NO 10975)

5'-B GTT TCB TCT TGG CTT-3' (FRAG NO 159S)(SEQ ID O 10976)

5'-GTT TCB TCT TGG CTT-3' (FRAG NO 1599)(SEQ ID NO 10977)

5'-TT TCB TCT TGG CTT-3' (FRAG NO 1600)(SEQ ID NO 10978) 5'-T TCB TCT TGG CTT-3' (FRAG NO 1601)(SEQ ID NO 10979)

5'-TCB TCT TGG CTT-3' (FRAG NO 1602)(SEQ ID NO 10980)

5'-GGG GGB GTT TCB TCT TGG CT-3' (FRAG NO 1603)(SEQ ID NO 10981)

5'-GG GGB GTT TCB TCT TGG CT-3' (FRAG NO 1604)(SEQ DDNO 10982)

5'-G GGB GTT TCB TCT TGG CT-3' (FRAG NO 1605)(SEQ ID NO 10983) 5'-GGB GTT TCB TCT TGG CT-3' (FRAG NO 1606)(SEQ ID NO 10984)

5'-GB GTT TCB TCT TGG CT-3' (FRAG NO 1607)(SEQ DD NO 10985)

5'-B GTT TCB TCT TGG CT-3' (FRAG NO 160S)(SEQ ID NO 10986)

5'-GTT TCB TCT TGG CT-3' (FRAG NO 1609)(SEQ ID NO 10987)

5'-TT TCB TCT TGG CT-3' (FRAG NO 1610)(SEQ IDNO 1098S) 5'-T TCB TCT TGG CT-3' (FRAG NO 1611)(SEQ ID NO 10989)

5'-GGG GGB GTT TCB TCT TGG C-3' (FRAG NO 1612)(SEQ ID NO 10990)

5'-GG GGB GTT TCB TCT TGG C-3' (FRAG NO 1613)(SEQ ID NO 10991)

5'-G GGB GTT TCB TCT TGG C-3' (FRAG NO 1614)(SEQ ID NO 10992)

5'-GGB GTT TCB TCT TGG C-3' (FRAG NO 1615)(SEQ ID NO 10993) 5'-GB GTT TCB TCT TGG C-3' (FRAG NO !616)(SEQ ID NO 10994)

5'-B GTT TCB TCT TGG C-3' (FRAG NO 1617)(SEQ ID NO 10995)

5'-GTT TCB TCT TGG C-3' (FRAG NO 1618)(SEQ DD NO 10996)

5'-TT TCB TCT TGG C-3' (FRAG NO 1619)(SEQ ID NO 10997)

5'-GGG GGB GTT TCB TCT TGG-3' (FRAG NO 1620)(SEQ ID NO 10998) 5'-GG GGB GTT TCB TCT TGG-3' (FRAG NO 1621)(SEQ DD NO 10999)

5'-G GGB GTT TCB TCT TGG-3' (FRAG NO 1622)(SEQ ID NO 11000)

5'-GGB GTT TCB TCT TGG-3' (FRAG NO 1623)(SEQ DD NO 11001)

5'-GB GTT TCB TCT TGG-3' (FRAG NO 1624)(SEQ DD NO 11002)

5'-B GTT TCB TCT TGG-3' (FRAG NO 1625)(SEQ D NO 11003) 5'-GTT TCB TCT TGG-3' (FRAG NO 1626)(SEQ ID NO 11004)

S'-GGG GGB GTT TCB TCT TG-3' (FRAG NO 1627)(SEQ ID NO 11005)

5'-GG GGB GTT TCB TCT TG-3' (FRAG NO 1628)(SEQ NO 11006)

5'-G GGB GTT TCB TCT TG-3' (FRAG NO 1629)(SEQ DD NO 11007)

5'-GGB GTT TCB TCT TG-3' (FRAG NO 1630)(SEQ ID NO 11008) 5'-GB GTT TCB TCT TG-3' (FRAG NO 1631)(SEQ DD NO 11009)

5'-B GTT TCB TCT TG-3' (FRAG NO 1632)(SEQ ID NO 11010)

5'-GGG GGB GTT TCB TCT T-3' (FRAG NO 1633)(SEQ ID NO 11011)

5'-GG GGB GTT TCB TCT T-3' (FRAG NO 1634)(SEQ DD NO 11012)

5'-G GGB GTT TCB TCT T-3' (FRAG NO 1635)(SEQ ID NO 11013) 5'-G GGB GTT TCB TCT T-3' (FRAG NO 1636)(SEQ ID NO 11014)

5'-GGB GTT TCB TCT T-3' (FRAG NO 1637)(SEQ DD NO 11015)

5'-GB GTT TCB TCT T-3' (FRAG NO 1638)(SEQ ID NO 11016)

5'-GGG GGB GTT TCB TCT-3' (FRAG NO 1639)(SEQ ID NO 11017)

5'-GG GGB GTT TCB TCT-3' (FRAG NO 1640)(SEQ ED NO 11018) 5'-G GGB GTT TCB TCT-3' (FRAG NO 1641)(SEQ DD NO 11019)

5'-GGB GTT TCB TCT-3' (FRAG NO 1642)(SEQ ID NO 11020)

5'-GGG GGB GTT TCB TC-3' (FRAG NO 1643)(SEQ DD NO 11021)

5'-GG GGB GTT TCB TC-3' (FRAG NO 1644)(SEQ ID O 11022)

5'-G GGB GTT TCB TC-3' (FRAG NO 1645)(SEQ ID NO 11023) 5'-GGG GGB GTT TCB T-3' (FRAG NO 1646)(SEQ ED NO 11024)

5'-GG GGB GTT TCB T-3* (FRAG NO 1647)(SEQ ID NO 11025)

5'-GGG GGB GTT TCB-3' (FRAG NO 1648)(SEQ ID NO 11026)

5'-TCT CCC CTT GTT CCT CCC C-3' (FRAG NO 1649)(SEQ DDNO 11027)

5'-TCT CCT GCT CTG GTG TCT CCT C-3' (FRAG NO 1650)(SEQ ID NO 11028) 5'-TTC CCT CCC TCC CCT GCC-3' (FRAG NO 1651)(SEQ ID NO 11029)

5'-GTG TTG TCT GTG GGT GTC C-3' (FRAG NO 1652)(SEQ DDNO 11030)

5'-GTT TCG CTC TTG TTG CCC-3' -3' (FRAG NO 1653)(SEQ ID NO 10891)

5'-TGG GCC CTT CCC TGC TGG-3' (FRAG NO 1654)(SEQ DD NO 11032)

5'-GGG GGB G-3' (FRAG NO 1912)(SEQ ID NO 11294) 5'-GTG GGT GTC C-3' (FRAG NO 1913) (SEQ ID NO 11295)

BP-1 Nucleic Acids and Antisense Oligonucleotide Fragments

5'-CCGTGTTGTC BGTGGTGCTG CCCGTTTGBG GTBTGGCGCT CCBCCBBTTC CCTTTTCTCC TTGTTTTCCG TTTCTCTTGC CGTCTGTGGT T-3' (FRAG NO 1914) (SEQ ID NO 11296)

5'-CCCGTTTGBGGTBTGGC-3'(FRAG NO 1915) (SEQ ID NO 11297) S'-GCTCCBCCBBTTCCCTTTTCTCC-3'(FRAG NO 1916) (SEQ ID NO 11298)

5'-TTGTTTTCCGTTTCTCTTG-3'(FRAG NO 1917) (SEQ DD NO 11299) S'-CCGTCTGTGGTT-3'(FRAG NO 1918) (SEQ DD NO 11300) 5'-CCCGTTTGAGGTATGGC-3'(FRAG NO 1919) (SEQ DD O 11301) 5'-GCTCCBCCAATTCCCTTTTCTCC-3'(FRAG NO 1920) (SEQ ID NO 11302) C/EBPNucleic Acids and Antisense Oligonucleotide Antisense Oligonucleotide Fragments

5'-GGGCCCBGCCCCGCCGCCTTTTCTBGCCCC GGCC-3' (FRAG NO 1921) (SEQ ID NO 11303) 5'-GGGCCCBGCCCCGCCGCCTTTTCTBGCCCC GGC-3' (FRAG NO 1922) (SEQ DD NO 11304) 5'-GGGCCCB GCCCCGCCGCCTTTTCTBGCCCCGG-3' (FRAG NO 1923) (SEQ DD NO 11305) 5'-GGGCCCBGCCCCGCCGCCTTTTCTBGCCCCG-3' (FRAG NO 1924) (SEQ ID NO 11306) 5'-GGGCCCBGCCCCGCCGCCTTTTCTBGCCCC-3' (FRAG NO 1925) (SEQ DD NO 11307)

5'-GGGCCCBGCCCCGCCGCCTTTTCTBGCCC-3' (FRAG NO 1926) (SEQ DDNO 11308) 5'-GGGCCCBGCCCCGCCGCCTTTTCTBGCC-3' (FRAG NO 1927) (SEQ DD NO 11309) 5'-GGGCCCBGCCCCGCCGCCTTTTCTBGC-3' (FRAG NO 1928) (SEQ DD NO 11310) 5'-GGGCCCBGCCCCGCCGCCTTTTCTBG-3' (FRAG NO 1929) (SEQ DD NO 11311) 5'-GGGCCCBGCCCCGCCGCCTTTTCTB-3' (FRAG NO 1930) (SEQ DD NO 11312)

5'-GGGCCCBGCCCCGCCGCCTTTTCT-3' (FRAG NO 1931) (SEQ ID NO 11311) 1944)

5'-GGGCCCBGCCCCGCCGCCTTTTC-3' (FRAG NO 1932) (SEQ DD NO 11314)

5'-GGGCCCBGCCCCGCCGCCTTTT-3' (FRAG NO 1933) (SEQ ID NO 11315) 5'-GGGCCCBGCCCCGCCGCCTTT-3' (FRAG NO 1934) (SEQ DD NO 11316) [1945)]

5'-GGGCCCBGCCCCGCCGCCTT-3' (FRAG NO 1935) (SEQ DD NO 11317)

5'-GGGCCCBGCCCCGCCGCCT-3' (FRAG NO 1936) (SEQ ID NO 11318)

5'-GGGCCCBGCCCCGCCGCC-3' (FRAG NO 1937) (SEQ DD NO 11319)

5'-GGGCCCBGCCCCGCCGC-3' (FRAG NO 1938) (SEQ ED NO 11320) 5'-GGGCCCBGCCCCGCCG-3' (FRAG NO 1939) (SEQ ID NO 11321) 5'-GGGCCCBGCCCCGCC-3' (FRAG NO 1940) (SEQ DD NO 11322)

5'-GGGCCCBGCCCCGC-3' (FRAG NO 1941) (SEQ ED NO 11323)

5'-GGGCCCBGCCCCG-3' (FRAG NO 1942) (SEQ DD NO 11324)

5'-GGGCCCBGCCCC-3' (FRAG NO 1943) (SEQ ID NO 11325) 5'-GGGCCCBGCCC-3' (FRAG NO 1944) (SEQ ID NO 11326)

5'-GGCCCBGCCCCGCCGCCTTTTCTBGCCCCGGC-3' (FRAG NO 1945) (SEQ ID NO 11327)

5'-GCCCBGCCCCGCCGCCTTTTCTBGCCCCGGC-3' (FRAG NO 1946) (SEQ DD NO 11328)

5'-CCCBGCCCCGCCGCCTTTTCTBGCCCCGGC-3' (FRAG NO 1947) (SEQ ID NO 11329)

5'-CCBGCCCCGCCGCCTTTTCTBGCCCCGGC-3' (FRAG NO 1948) (SEQ ED NO 11330) 5'-CBGCCCCGCCGCCTTTTCTBGCCCCGGC-3' (FRAG NO 1948) (SEQ DD NO 11331)

5'-BGCCCCGCCGCCTTrTCTBGCCCCGGC-3' (FRAG NO 1950) (SEQ ID NO 11332)

5'-GCCCCGCCGCCTTTTCTBGCCCCGGC-3' (FRAG NO 1951) (SEQ DD NO 11333)

5'-CCCCGCCGCCTTTTCTBGCCCCGGC-3' (FRAG NO 1952) (SEQ ID NO 11334)

5'-CCCGCCGCCTTTTCTBGCCCCGGC-3' (FRAG NO 1953) (SEQ ID NO 11335) 5'-CCGCCGCCTTTTCTBGCCCCGGC-3' (FRAG NO 1954) (SEQ ID NO 11336)

5'-CGCCGCCTTTTCTBGCCCCGGC-3' (FRAG NO 1955) (SEQ DD NO 11337)

5'-GCCGCCTTTTCTBGCCCCGGC-3' (FRAG NO 1956) (SEQ DD NO 11338)

5'-CCGCCTTTTCTBGCCCCGGC-3' (FRAG NO 1957) (SEQ ID NO 11339)

5'-CGCCTTTTCTBGCCCCGGC-3' (FRAG NO 1958) (SEQ ID NO 11340) 5'-GCCTTTTCTBGCCCCGGC-3' (FRAG NO 1959) (SEQ ID NO 11341)

5'-CCTTTTCTBGCCCCGGC-3' (FRAG NO 1960) (SEQ DD NO 11342)

5'-CTTTTCTBGCCCCGGC-3' (FRAG NO 1961) (SEQ ID NO 11343)

5'-TTTTCTBGCCCCGGC-3' (FRAG NO 1962) (SEQ ID NO 11344)

5'-TTTCTBGCCCCGGC-3' (FRAG NO 1963) (SEQ DD NO 11345) 5'-TTCTBGCCCCGGC-3' (FRAG NO 1964) (SEQ ID NO 11346)

5'-TCTBGCCCCGGC-3' (FRAG NO 1965) (SEQ ID NO 11347)

5'-CTBGCCCCGGC-3' (FRAG NO 1966) (SEQ ID NO 11348)

5'-GCGBGGCTGTCBCCTCGCTGGGCCC-3' (FRAG NO 1967) (SEQ ID NO 11349)

S'-GCGBGGCTGTCBCCTCGCTGGGCC-3' (FRAG NO 1968) (SEQ DD NO 11350) 5'-GCGBGGCTGTCBCCTCGCTGGGC-3' (FRAG NO 1969) (SEQ ID NO 11351)

5'-GCGBGGCTGTCBCCTCGCTGGG-3' (FRAG NO 1970) (SEQ DDNO 11352)

5'-GCGBGGCTGTCBCCTCGCTGG 3' (FRAG NO 1971) (SEQ DD NO 11353)

5'-GCGBGGCTGTCBCCTCGCTG-3' (FRAG NO 1972) (SEQ ID NO 11354)

5'-GCGBGGCTGTCBCCTCGCT-3' (FRAG NO 1973) (SEQ ID NO 11355) 5'-GCGBGGCTGTCBCCTCGC-3' (FRAG NO 1974) (SEQ ID NO 11356)

5'-GCGBGGCTGTCBCCTCG-3' (FRAG NO 1975) (SEQ ID NO 11357)

5'-GCGBGGCTGTCBCCTC-3' (FRAG NO 1976) (SEQ ID NO 11358)

5'-GCGBGGCTGTCBCCT-3' (FRAG NO 1977) (SEQ ID NO 11359)

5'-GCGBGGCTGTCBCC-3' (FRAG NO 1978) (SEQ ID NO 11360) 5'-GCGBGGCTGTCBC-3' (FRAG NO 1979) (SEQ ID NO 11361)

5'-GCGBGGCTGTCB-3' (FRAG NO 1980) (SEQ ID NO 11362)

5'-GCGBGGCTGTC-3' (FRAG NO 1981) (SEQ ID NO 11363)

5'-GCGBGGCTGT-3' (FRAG NO 1982) (SEQ ID NO 11364)

5'-CGBGGCTGTCBCCTCGCTGGGCCC-3' (FRAG NO 1983) (SEQ DD NO 11365) 5'-GBGGCTGTCBCCTCGCTGGGCCC-3' (FRAG NO 1984) (SEQ ID NO 11366)

5'-BGGCTGTCBCCTCGCTGGGCCC-3' (FRAG NO 1985) (SEQ D NO 11367)

5'-GGCTGTCBCCTCGCTGGGCCC-3' (FRAG NO 1986) (SEQ ED NO 11368)

5'-GCTGTCBCCTCGCTGGGCCC-3' (FRAG NO 1987) (SEQ ID NO 11369)

5'-CTGTCBCCTCGCTGGGCCC-3' (FRAG NO 1988) (SEQ ID NO 11370) 5'-TGTCBCCTCGCTGGGCCC-3' (FRAG NO 1989) (SEQ DD NO 11371)

5'-GTCBCCTCGCTGGGCCC-3' (FRAG NO 1990) (SEQ ID NO 11372)

5'-TCBCCTCGCTGGGCCC-3' (FRAG NO 1991) (SEQ ID NO 11373)

5' CBCCTCGCTGGGCCC-3' (FRAG NO 1992) (SEQ ID NO 11374)

5'-BCCTCGCTGGGCCC-3' (FRAG NO 1993) (SEQ ID NO 11375) 5'-CCTCGCTGGGCCC-3' (FRAG NO 1994) (SEQ ID NO 11376)

5'-CTCGCTGGGCCC-3' (FRAG NO 1995) (SEQ DD NO 11377)

5'-TCGCTGGGCCC-3' (FRAG NO 1996) (SEQ ED NO 11378)

5*-CGCTGGGCCC-3' (FRAG NO 1997) (SEQ ID NO 11379)

5'-GCGCGGCCGTCBTGGCGGCGTCGGGCCGGGC-3' (FRAG NO 1998) (SEQ DD NO 11380) 5'-GCGCGGCCGTCBTGGCGGCGTCGGGCCGGG-3' (FRAG NO 1999) (SEQ ID NO 11381)

5'-GCGCGGCCGTCBTGGCGGCGTCGGGCCGG-3' (FRAG NO 2000) (SEQ ID NO 11382)

5*-GCGCGGCCGTCBTGGCGGCGTCGGGCCG-3' (FRAG NO 2001) (SEQ DDNO 11383)

5'-GCGCGGCCGTCBTGGCGGCGTCGGGCC-3' (FRAG NO 2002) (SEQ ID NO 11384)

5'-GCGCGGCCGTCBTGGCGGCGTCGGGC-3' (FRAG NO 2003) (SEQ ID NO 11385) 5'-GCGCGGCCGTCBTGGCGGCGTCGGG-3' (FRAG NO 2004) (SEQ DD NO 11386)

5'-GCGCGGCCGTCBTGGCGGCGTCGG-3' (FRAG NO 2005) (SEQ ID NO 11387)

5'-GCGCGGCCGTCBTGGCGGCGTCG-3' (FRAG NO 2006) (SEQ DD NO 11388)

5'-GCGCGGCCGTCBTGGCGGCGTC-3' (FRAG NO 2007) (SEQ DD NO 11389)

5'-GCGCGGCCGTCBTGGCGGCGT-3' (FRAG NO 2008) (SEQ ID NO 11390) 5'-GCGCGGCCGTCBTGGCGGCG-3' (FRAG NO 2009) (SEQ DD NO 11391)

5'-GCGCGGCCGTCBTGGCGGC-3' (FRAG NO 2010) (SEQ DD NO 11392)

5'-GCGCGGCCGTCBTGGCGG-3' (FRAG NO 2011) (SEQ ED NO 11393)

5'-GCGCGGCCGTCBTGGCG-3' (FRAG NO 2012) (SEQ ID NO 11394)

5'-GCGCGGCCGTCBTGGC-3' (FRAG NO 2013) (SEQ ID NO 11395) 5'-GCGCGGCCGTCBTGG-3' (FRAG NO 2014) (SEQ ID NO 11396)

5'-GCGCGGCCGTCBTG-3' (FRAG NO 2015) (SEQ DD NO 11397)

5'-GCGCGGCCGTCBT-3' (FRAG NO 2016) (SEQ ID NO 11398)

5'-GCGCGGCCGTCB-3' (FRAG NO 2017) (SEQ ID NO 11399)

5'-GCGCGGCCGTC-3' (FRAG NO 2018) (SEQ ID NO 11400) 5'-GCGCGGCCGT-3' (FRAG NO 2019) (SEQ ID O 11401)

5'-CGCGGCCGTCBTGGCGGCGTCGGGCCGGGC-3' (FRAG NO 2020) (SEQ DD NO 11402)

5'-GCGGCCGTCBTGGCGGCGTCGGGCCGGGC-3' (FRAG NO 2021) (SEQ ID NO 11403)

5'-CGGCCGTCBTGGCGGCGTCGGGCCGGGC-3' (FRAG NO 2022) (SEQ DD NO 11404)

5'-GGCCGTCBTGGCGGCGTCGGGCCGGGC-3' (FRAG NO 2023) (SEQ ID NO 11405) 5'-GCCGTCBTGGCGGCGTCGGGCCGGGC-3' (FRAG NO 2024) (SEQ ED NO 11406)

5'-CCGTCBTGGCGGCGTCGGGCCGGGC-3' (FRAG NO 2025) (SEQ ID NO 11407)

5'-CGTCBTGGCGGCGTCGGGCCGGGC-3' (FRAG NO 2026) (SEQ ID NO 11408)

5'-GTCBTGGCGGCGTCGGGCCGGGC-3' (FRAG NO 2027) (SEQ ID NO 11409)

5'-TCBTGGCGGCGTCGGGCCGGGC-3' (FRAG NO 2028) (SEQ ID NO 11410) 5'-CBTGGCGGCGTCGGGCCGGGC-3' (FRAG NO 2029) (SEQ DD NO 11411)

5'-BTGGCGGCGTCGGGCCGGGC-3' (FRAG NO 2030) (SEQ DD O 11412)

5'-TGGCGGCGTCGGGCCGGGC-3' (FRAG NO 2031) (SEQ DD NO 11413)

5'-GGCGGCGTCGGGCCGGGC-3' (FRAG NO 2032) (SEQ ID NO 11414) 5'-GCGGCGTCGGGCCGGGC-3' (FRAG NO 2033) (SEQ ED NO 11415)

5'-CGGCGTCGGGCCGGGC-3' (FRAG NO 2034) (SEQ DD NO 11416)

5'-GGCGTCGGGCCGGGC-3' (FRAG NO 2035) (SEQ ID NO 11417)

5'-GCGTCGGGCCGGGC-3' (FRAG NO 2036) (SEQ DD NO 11418)

5'-CGTCGGGCCGGGC-3' (FRAG NO 2037) (SEQ DD NO 11419) 5'-GTCGGGCCGGGC-3' (FRAG NO 2038) (SEQ DD NO 11420)

5'-TCGGGCCGGGC-3' (FRAG NO 2039) (SEQ ED NO 11421)

5'-CGGGCCGGGC-3' (FRAG NO 2040) (SEQ ED NO 11422)

5'-CCGCBGGCCBGGGCGCGCCGCCGGCCGGGCCG-3' (FRAG NO 2041) (SEQ ED NO 11423)

5'-CCGCBGGCCBGGGCGCGCCGCCGGCCGGGCC-3' (FRAG NO 2042) (SEQ DD NO 11424) 5'-CCGCBGGCCBGGGCGCGCCGCCGGCCGGGC-3' (FRAG NO 2043) (SEQ DD NO 11425)

5'-CCGCBGGCCBGGGCGCGCCGCCGGCCGGG-3' (FRAG NO 2044) (SEQ DD NO 11426)

5'-CCGCBGGCCBGGGCGCGCCGCCGGCCGG-3' (FRAG NO 2045) (SEQ DD NO 11427)

5'-CCGCBGGCCBGGGCGCGCCGCCGGCCG-3' (FRAG NO 2046) (SEQ DD NO 11428)

5'-CCGCBGGCCBGGGCGCGCCGCCGGCC-3' (FRAG NO 2047) (SEQ ID NO 11429) 5'-CCGCBGGCCBGGGCGCGCCGCCGGC-3' (FRAG NO 2048) (SEQ DD NO 11430)

5'-CCGCBGGCCBGGGCGCGCCGCCGG-3' (FRAG NO 2049) (SEQ ID NO 11431)

5'-CCGCBGGCCBGGGCGCGCCGCCG-3' (FRAG NO 2050) (SEQ ID NO 11432)

5'-CCGCBGGCCBGGGCGCGCCGCC-3' (FRAG NO 2051) (SEQ DD NO 11433)

5'-CCGCBGGCCBGGGCGCGCCGC-3' (FRAG NO 2052) (SEQ ID NO 11434) 5'-CCGCBGGCCBGGGCGCGCCG-3' (FRAG NO 2053) (SEQ ID NO 11435)

5'-CCGCBGGCCBGGGCGCGCC-3' (FRAG NO 2054) (SEQ ID NO 11436)

S'-CCGCBGGCCBGGGCGCGC-3' (FRAG NO 2055) (SEQ ID NO 11437)

5'-CCGCBGGCCBGGGCGCG-3' (FRAG NO 2056) (SEQ ID NO 11438)

5'-CCGCBGGCCBGGGCGC-3' (FRAG NO 2057) (SEQ ID NO 11439) 5'-CCGCBGGCCBGGGCG-3' (FRAG NO 2058) (SEQ ID NO 11440)

5'-CCGCBGGCCBGGGC-3' (FRAG NO 2059) (SEQ ID NO 11441)

5'-CCGCBGGCCBGGG-3' (FRAG NO 2060) (SEQ ID NO 11442)

5'-CCGCBGGCCBGG 3' (FRAG NO 2061) (SEQ DD NO 11443)

5'-CCGCBGGCCBG-3' (FRAG NO 2062) (SEQ ID NO 11444) 5'-CCGCBGGCCB-3' (FRAG NO 2063) (SEQ ID NO 11445)

5'-CCGCBGGCC-3' (FRAG NO 2064) (SEQ ID NO 11446)

5'-CGCBGGCCBGGGCGCGCCGCCGGCCGGGCCG-3' (FRAG NO 2065) (SEQ DD O 11447)

5'-GCBGGCCBGGGCGCGCCGCCGGCCGGGCCG-3' (FRAG NO 2066) (SEQ DD NO 11448)

5'-CBGGCCBGGGCGCGCCGCCGGCCGGGCCG-3' (FRAG NO 2067) (SEQ ID NO 11449) S'-BGGCCBGGGCGCGCCGCCGGCCGGGCCG-3' (FRAG NO 2068) (SEQ ID NO 11450)

5'-GGCCBGGGCGCGCCGCCGGCCGGGCCG-3' (FRAG NO 2069) (SEQ ID NO 11451)

5' GCCBGGGCGCGCCGCCGGCCGGGCCG-3' (FRAG NO 2070) (SEQ ID NO 11452)

5'-CCBGGGCGCGCCGCCGGCCGGGCCG-3' (FRAG NO 2071) (SEQ DD NO 11453)

5'-CBGGGCGCGCCGCCGGCCGGGCCG-3' (FRAG NO 2072) (SEQ ID NO 11454) 5'-BGGGCGCGCCGCCGGCCGGGCCG-3' (FRAG NO 2073) (SEQ DD NO 11455)

5'-GGGCGCGCCGCCGGCCGGGCCG-3' (FRAG NO 2074) (SEQ ID NO 11456)

5'-GGCGCGCCGCCGGCCGGGCCG-3' (FRAG NO 2075) (SEQ ID NO 11457)

5'-GCGCGCCGCCGGCCGGGCCG-3' (FRAG NO 2076) (SEQ DD NO 11458)

5'-CGCGCCGCCGGCCGGGCCG 3' (FRAG NO 2077) (SEQ ID NO 11459) S'-GCGCCGCCGGCCGGGCCG-3' (FRAG NO 2078) (SEQ ID NO 11460)

5'-CGCCGCCGGCCGGGCCG-3' (FRAG NO 2079) (SEQ ID NO 11461)

5'-GCCGCCGGCCGGGCCG-3' (FRAG NO 2080) (SEQ ID NO 11462)

5'-CCGCCGGCCGGGCCG-3' (FRAG NO 2081) (SEQ ID NO 11463)

5'-CGCCGGCCGGGCCG-3' (FRAG NO 2082) (SEQ ID NO 11464) 5'-GCCGGCCGGGCCG-3' (FRAG NO 2083) (SEQ ID NO 11465)

5'-CCGGCCGGGCCG-3' (FRAG NO 2084) (SEQ ID NO 11466)

5'-CGGCCGGGCCG-3' (FRAG NO 2085) (SEQ ID NO 11467)

5'-GGCCGGGCCG-3' (FRAG NO 2086) (SEQ ID NO 11468)

5'-GGGCGCBGGCTCCGCB-3' (FRAG NO 2087) (SEQ ID NO 11469) S'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3'(FRAG NO 2088)(SEQ DD NO 11470)

S'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCG-3' (FRAG NO 2089)(SEQ ID NO 11471)

S'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCC-3' (FRAG NO 2090)(SEQ ID NO 11472)

5'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCC-3' (FRAG NO 2091) (SEQ ID NO 11473)

5'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGC-3' (FRAG NO 2092) (SEQ ID NO 11474) 5'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGG-3' (FRAG NO 2093) (SEQ ID NO 11475)

5'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCG-3' (FRAG NO 2094) (SEQ ID O 11476)

5'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCC-3' (FRAG NO 2095) (SEQ ID NO 11477)

5'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCC-3' (FRAG NO 2096) (SEQ ID NO 11478)

S'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGC-3' (FRAG NO 2097) (SEQ ID NO 11479) 5'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCG-3' (FRAG NO 2098) (SEQ ID NO 11480)

5'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCC-3' (FRAG NO 2099) (SEQ DD NO 11481)

5'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCC-3' (FRAG NO 2100) (SEQ ID NO 11482)

S'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGC-3' (FRAG NO 2101) (SEQ DD NO 11483)

S'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTTG-3' (FRAG NO 2102) (SEQ ID NO 11484) S'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCTT-3' (FRAG NO 2103) (SEQ ID NO 11485)

5'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGCT-3' (FRAG NO 2104) (SEQ ID NO 11486)

5'-GGGCCCCTGGCTCGGCCCCGCGGCCCGGC-3' (FRAG NO 2105) (SEQ ID NO 11487)

5'-GGGCCCCTGGCTCGGCCCCGCGGCCCGG-3' (FRAG NO 2106) (SEQ ID NO 11488)

5'-GGGCCCCTGGCTCGGCCCCGCGGCCCG-3' (FRAG NO 2107) (SEQ ID NO 11489) 5'-GGGCCCCTGGCTCGGCCCCGCGGCCC-3' (FRAG NO 2108) (SEQ ID O 11490)

5'-GGGCCCCTGGCTCGGCCCCGCGGCC-3' (FRAG NO 2109) (SEQ DD NO 11491)

5'-GGGCCCCTGGCTCGGCCCCGCGGC-3' (FRAG NO 2110) (SEQ ID O 11492)

5'-GGGCCCCTGGCTCGGCCCCGCGG-3' (FRAG NO 2111) (SEQ ID NO 11493)

5'-GGGCCCCTGGCTCGGCCCCGCG-3' (FRAG NO 2112) (SEQ ID NO 11494) 5'-GGGCCCCTGGCTCGGCCCCGC-3' (FRAG NO 2113) (SEQ ID NO 11495)

5'-GGGCCCCTGGCTCGGCCCCG-3' (FRAG NO 114) (SEQ DD NO 11496)

5'-GGGCCCCTGGCTCGGCCCC-3' (FRAG NO 2115) (SEQ ID NO 11497)

5'-GGGCCCCTGGCTCGGCCC-3' (FRAG NO 2116) (SEQ DD NO 11498)

5'-GGGCCCCTGGCTCGGCC-3' (FRAG NO 2117) (SEQ ED NO 11499) 5'-GGGCCCCTGGCTCGGC-3' (FRAG NO 2118) (SEQ ID NO 11500)

5'-GGGCCCCTGGCTCGG-3' (FRAG NO 2119) (SEQ ID NO 11501)

5'-GGGCCCCTGGCTCG-3' (FRAG NO 2120) (SEQ DDNO 11502)

5'-GGGCCCCTGGCTC-3' (FRAG NO 2121) (SEQ ID NO 11503)

5'-GGGCCCCTGGCT-3' (FRAG NO 2122) (SEQ ID NO 11504) 5'-GGCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3'(FRAG O 2123)(SEQ DD NO 11505)

5'-GCCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2124) (SEQ DDNO 11506)

5'-CCCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2125) (SEQ ED NO 11507)

5'-CCCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2126) (SEQ DD NO 11508)

5'-CCTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG 3' (FRAG NO 2127) (SEQ DDNO 11509) '-CTGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2128) (SEQ DD NO 11510) -TGGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2129) (SEQ LD NO 11511) '-GGCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2130) (SEQ ID NO 11512) '-GCTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2131) (SEQ ID NO 11513) -CTCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2132) (SEQ DD NO 11514) -TCGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2133) (SEQ ID NO 11515) '-CGGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2134) (SEQ ID NO 11516) '-GGCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2135) (SEQ DD NO 11517) '-GCCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2136) (SEQ DD NO 11518) '-CCCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2137) (SEQ DDNO 11519) '-CCCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2138) (SEQ ID NO 11520) '-CCGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2139) (SEQ DD NO 11521) '-CGCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2140) (SEQ DD NO 11522) '-GCGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2141) (SEQ ID NO 11523) '-CGGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2142) (SEQ DD NO 11524) '-GGCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2143) (SEQ DD NO 11525) '-GCCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2144) (SEQ ID NO 11526) '-CCCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2145) (SEQ DD NO 11527) '-CCGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2146) (SEQ DD NO 11528) '-CGGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2147) (SEQ DD NO 11529) '-GGCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2148) (SEQ ID O 11530) '-GCTTGCCCGCCCGGCCCGG-3' (FRAG NO 2149) (SEQ ID NO 11531) '-CTTGCCCGCCCGGCCCGG-3' (FRAG NO 2150) (SEQ ID NO 11532) '-TTGCCCGCCCGGCCCGG-3' (FRAG NO 2151) (SEQ ID NO 11533) '-TGCCCGCCCGGCCCGG-3' (FRAG NO 2152) (SEQ ID NO 11534) '-GCCCGCCCGGCCCGG-3' (FRAG NO 2153) (SEQ ID NO 11535) '-CCCGCCCGGCCCGG-3' (FRAG NO 2154) (SEQ ID NO 11536) '-CCGCCCGGCCCGG-3' (FRAG NO 2155) (SEQ ID NO 11537) '-CGCCCGGCCCGG-3' (FRAG NO 2156) (SEQ DD NO 11538) '-GCCCGGCCCGG-3' (FRAG NO 2157) (SEQ ID NO 11539) '-GGCGGGGGCGGCGGCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2158) (SEQ ID NO 11540) '-GGCGGGGGCGGCGGCGCCTGGCTCGCCTBGGGCCC-3' (FRAG NO 2159) (SEQ ID NO 11541) '-GGCGGGGGCGGCGGCGCCTGGCTCGCCTBGGGCC-3' (FRAG NO 2160) (SEQ ID NO 11542) '-GGCGGGGGCGGCGGCGCCTGGCTCGCCTBGGGC-3' (FRAG NO 2161) (SEQ TD NO 11543) '-GGCGGGGGCGGCGGCGCCTGGCTCGCCTBGGG-3' (FRAG NO 2162) (SEQ ID NO 11544) '-GGCGGGGGCGGCGGCGCCTGGCTCGCCTBGG-3' (FRAG NO 2163) (SEQ DD NO 11545) '-GGCGGGGGCGGCGGCGCCTGGCTCGCCTBG-3' (FRAG NO 2164) (SEQ DD NO 11546) '-GGCGGGGGCGGCGGCGCCTGGCTCGCCTB-3' (FRAG NO 2165) (SEQ ID NO 11547) '-GGCGGGGGCGGCGGCGCCTGGCTCGCCT-3' (FRAG NO 2166) (SEQ ID NO 11548) '-GGCGGGGGCGGCGGCGCCTGGCTCGCC-3' (FRAG NO 2167) (SEQ DD NO 11549) '-GGCGGGGGCGGCGGCGCCTGGCTCGC 3' (FRAG NO 2168) (SEQ ID NO 11550) '-GGCGGGGGCGGCGGCGCCTGGCTCG 3' (FRAG NO 2169) (SEQ ID NO 11551) '-GGCGGGGGCGGCGGCGCCTGGCTC-3' (FRAG NO 2170) (SEQ ID NO 11552) '-GGCGGGGGCGGCGGCGCCTGGCT-3' (FRAG NO 2171) (SEQ ID NO 11553) '-GGCGGGGGCGGCGGCGCCTGGC-3' (FRAG NO 2172) (SEQ IDNO 11554) '-GGCGGGGGCGGCGGCGCCTGG-3' (FRAG NO 2173) (SEQ ID NO 11555) '-GGCGGGGGCGGCGGCGCCTG-3' (FRAG NO 2174) (SEQ ID NO 11556) '-GGCGGGGGCGGCGGCGCCT-3' (FRAG NO 2175) (SEQ DD NO 11557) '-GGCGGGGGCGGCGGCGCC-3' (FRAG NO 2176) (SEQ ID NO 11558) '-GGCGGGGGCGGCGGCGC-3' (FRAG NO 2177) (SEQ ID NO 11559) '-GGCGGGGGCGGCGGCG-3' (FRAG NO 2178) (SEQ DD NO 11560) '-GGCGGGGGCGGCGGC-3' (FRAG NO 2179) (SEQ DD NO 11561) '-GGCGGGGGCGGCGG-3' (FRAG NO 2180) (SEQ ID NO 11562) '-GGCGGGGGCGGCG-3' (FRAG NO 2181) (SEQ ID NO 11563) '-GGCGGGGGCGGC-3' (FRAG NO 2182) (SEQ DDNO 11564) '-GGCGGGGGCGG-3' (FRAG NO 2183) (SEQ ID NO 11565) '-GCGGGGGCGGCGGCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2184) (SEQ ID NO 11566) '-CGGGGGCGGCGGCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2185) (SEQ ID NO 11567) '-GGGGGCGGCGGCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2186) (SEQ ID NO 11568) '-GGGGCGGCGGCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2187) (SEQ DD NO 11569) '-GGGCGGCGGCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2188) (SEQ ID NO 11570) '-GGCGGCGGCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2189) (SEQ ID NO 11571) '-GCGGCGGCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2190) (SEQ ID NO 11572) '-CGGCGGCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2191) (SEQ D O 11573) '-GGCGGCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2192) (SEQ DD NO 11574) '-GCGGCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2193) (SEQ ID NO 11575) '-CGGCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2194) (SEQ ID NO 11576) '-GGCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2195) (SEQ ID NO 11577) '-GCGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2196) (SEQ ID NO 11578) '-CGCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2197) (SEQ ID NO 11579) '-GCCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2198) (SEQ ID NO 11580) '-CCTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2199) (SEQ ID O 11581) '-CTGGCTCGCCTBGGGCCCC-3' (FRAG NO 2200) (SEQ ID NO 11582) '-TGGCTCGCCTBGGGCCCC-3' (FRAG NO 2201) (SEQ ID NO 11583) '-GGCTCGCCTBGGGCCCC-3' (FRAG NO 2202) (SEQ ID NO 11584) '-GCTCGCCTBGGGCCCC-3' (FRAG NO 2203) (SEQ ID NO 11585) '-CTCGCCTBGGGCCCC-3' (FRAG NO 2204) (SEQ ID NO 11586) '-TCGCCTBGGGCCCC-3' (FRAG NO 2205) (SEQ DD NO 11587) '-CGCCTBGGGCCCC-3' (FRAG NO 2206) (SEQ ID NO 11588) '-GCCTBGGGCCCC-3' (FRAG NO 2207) (SEQ ID NO 11589) '-CCTBGGGCCCC-3' (FRAG NO 2208) (SEQ ID NO 11590) '-CTBGGGCCCC-3' (FRAG NO 2209) (SEQ ID NO 11591) '-GGGTGGGCBCGGCGGCC-3' (FRAG NO 2210) (SEQ ID O 11592) '-GGTCGGCGBBGBGCTCGTCGTGGC-3' (FRAG NO 2211) (SEQ DD NO 11593) '-GGTCGGCGBBGBGCTCGTCGTGG-3' (FRAG NO 2212) (SEQ DD NO 11594) '-GGTCGGCGBBGBGCTCGTCGTG-3' (FRAG NO 2213) (SEQ DD NO 11595) '-GGTCGGCGBBGBGCTCGTCGT-3' (FRAG NO 2214) (SEQ ID NO 11596) '-GGTCGGCGBBGBGCTCGTCG-3' (FRAG NO 2215) (SEQ DD NO 11597) '-GGTCGGCGBBGBGCTCGTC-3' (FRAG NO 2216) (SEQ ID NO 11598) '-GGTCGGCGBBGBGCTCGT-3' (FRAG NO 2217) (SEQ TD NO 11599) '-GGTCGGCGBBGBGCTCG-3' (FRAG NO 2218) (SEQ DDNO 11600) '-GGTCGGCGBBGBGCTC-3' (FRAG NO 2219) (SEQ ID NO 11601) '-GGTCGGCGBBGBGCT-3' (FRAG NO 2220) (SEQ ID NO 11602) '-GGTCGGCGBBGBGC-3' (FRAG NO 2221) (SEQ D NO 11603) '-GGTCGGCGBBGBG-3' (FRAG NO 2222) (SEQ ID NO 11604) '-GGTCGGCGBBGB-3' (FRAG NO 2223) (SEQ DD NO 11605) '-GGTCGGCGBBG-3' (FRAG NO 2224) (SEQ ID NO 11606) '-GTCGGCGBBGBGCTCGTCGTGGC-3' (FRAG NO 2225) (SEQ ID NO 11607) '-TCGGCGBBGBGCTCGTCGTGGC-3' (FRAG NO 2226) (SEQ ID NO 11608) 5'-CGGCGBBGBGCTCGTCGTGGC-3' (FRAG NO 2227) (SEQ D NO 11609)

5'-GGCGBBGBGCTCGTCGTGGC-3' (FRAG NO 2228) (SEQ ID NO 11610)

5'-GCGBBGBGCTCGTCGTGGC-3' (FRAG NO 2229) (SEQ DD NO 11611)

5'-CGBBGBGCTCGTCGTGGC-3' (FRAG NO 2230) (SEQ ED NO 11612) 5'-GBBGBGCTCGTCGTGGC-3' (FRAG NO 2231) (SEQ DD NO 11613)

5'-BBGBGCTCGTCGTGGC~3' (FRAG NO 2232) (SEQ ED NO 11614)

5'-BGBGCTCGTCGTGGC-3' (FRAG NO 2233) (SEQ ED NO 11615)

5'-GBGCTCGTCGTGGC-3' (FRAG NO 2234) (SEQ ED NO 11616)

5'-BGCTCGTCGTGGC-3' (FRAG NO 2235) (SEQ DD NO 11617) 5'-GCTCGTCGTGGC-3' (FRAG NO 2236) (SEQ ED NO 11618)

5'-CTCGTCGTGGC-3' (FRAG NO 2237) (SEQ ED NO 11619)

5'-TCGTCGTGGC-3' (FRAG NO 2238) (SEQ ED NO 11620)

5'-GGGGCCCCGCGCCGCCCGCC-3' (FRAG NO 2239) (SEQ ED NO 11621)

5'-GGGGCCCCGCGCCGCCCGC-3' (FRAG NO 2240) (SEQ ID NO 11622) 5'-GGGGCCCCGCGCCGCCCG-3' (FRAG NO 2241) (SEQ ID NO 11623)

5'-GGGGCCCCGCGCCGCCC-3' (FRAG NO 2242) (SEQ ID NO 11624)

5'-GGGGCCCCGCGCCGCC-3' (FRAG NO 2243) (SEQ ID NO 11625)

5'-GGGGCCCCGCGCCGC-3' (FRAG NO 2244) (SEQ ID NO 11626)

5'-GGGGCCCCGCGCCG-3' (FRAG NO 2245) (SEQ DD NO 11627) 5'-GGGGCCCCGCGCC-3' (FRAG NO 2246) (SEQ ID NO 11628)

5'-GGGGCCCCGCGC-3' (FRAG NO 2247) (SEQ ID NO 11629)

5'-GGGCCCCGCGCCGCCCGCC-3' (FRAG NO 2248) (SEQ ID NO 11630)

5'-GGCCCCGCGCCGCCCGCC-3' (FRAG NO 2249) (SEQ ID NO 11631)

5'-GCCCCGCGCCGCCCGCC-3' (FRAG NO 2250) (SEQ DD NO 11632) 5'-CCCCGCGCCGCCCGCC-3' (FRAG NO 2251) (SEQ ID NO 11633)

5'-CCCGCGCCGCCCGCC-3' (FRAG NO 2252) (SEQ ID NO 11634)

5'-CCGCGCCGCCCGCC-3' (FRAG NO 2253) (SEQ ID NO 11635)

5'-CGCGCCGCCCGCC-3' (FRAG NO 2254) (SEQ ID NO 11636)

5'-GCGCCGCCCGCC-3' (FRAG NO 2255) (SEQ ED NO 11637) 5'-CGCCGCCCGCC-3' (FRAG NO 2256) (SEQ DD NO 11638)

5'-GCCGCCCGCC-3' (FRAG NO 2257) (SEQ ID NO 11639)

5'-GGGGCGCGCGGGGCCGCCGGG-3' (FRAG NO 2258) (SEQ DD NO 11640)

5'-GGCGGGGBGCGGCBGGGCCCGGGCCC-3' (FRAG NO 2259) (SEQ ID NO 11641)

5'-GGCGCGTCGCCGTCGCCCCBGTCGGGCTCGCGC-3' (FRAG NO 2260) (SEQ ID NO 11642) 5'-GCGCGGGCBBCBGCGBGCCGGGCGCG-3' (FRAG NO 2261) (SEQ ID NO 11643)

5'-GCGCBCGGGCCCBCCTGCGCGGGC-3' (FRAG NO 2262) (SEQ DD NO 11644)

5'-GGGCGGGGTGGGCTGCCCTGCGGCCGCC-3' (FRAG NO 2263) (SEQ ID NO 11645)

5'-GGGCTGCTGCGCGGCGGCTCCGGCGA-3' (FRAG NO 2264) (SEQ ID NO 11646)

S'-CTCCCGGGCGGGGCCGGGCGCGGGG-3' (FRAG NO 2265) (SEQ ID NO 11647) 5'-GGGCTGCCGCGGTCCGGGCCCCTCTTGCCGGCG-3' (FRAG NO 2266) (SEQ ID NO 11648)

S'-GCGCTCGCGCCGCTGCCGG-3' (FRAG NO 2267) (SEQ ID NO 11649)

5'-GCGCCGCTTGGCCTTGTCGCGGC-3' (FRAG NO 2268) (SEQ DD NO 11650)

5'-GCTGCTCCBCGCGCTGG-3' (FRAG NO 2269) (SEQ DD NO 11651)

5'-GCCGGBGGCCGGCCBGGTCCCGCG-3' (FRAG NO 2270) (SEQ ID NO 11652) 5'-CCCGGCGGCCGGCBGGBBGGGCGGGCTGGGC-3' (FRAG NO 2271) (SEQ ID NO 11653)

5'-GTCTCTCCCGCCCCGGCCGCGCG 3' (FRAG NO 2272) (SEQ ID NO 11654)

5'-GGGCGTCCGCTCCGGGCCGTCGGG-3' (FRAG NO 2273) (SEQ DD NO 11655)

S' GCGGGCACGCGGCGGCTCTGGCGTCGGC-3' (FRAG NO 2274) (SEQ DDNO 11656)

Bradykinin Receptor Nucleic Acids and Antisense Oligonucleotide Fragments S'-GGTGBCBTTG BGCBTGTCGG CGCGGTCCCG TTBBGBGTGG GCCCGCCAGC CCAGCCACTC CACTTGGGGG CGGGTGGCCA GCACGAACAG CACCCAGAGG

AAGGGGGGCG GCCCAGAAGG GCAGCCCGCA GGCCAGGATC AGGTCTGCTG CGGCCGGAGA TAATGGCATT CACCACGCGG CGGCCCAGCG CACGCCGCGC ATCCGGCCCG GGTTCTGACC TGCAGCCCCC GTCTCCTTGG CATTCCTGGG CCCCAGTCAC TCCTCTCCCT GCCCCCCTTG CTGGGGCAGG GACGGGGTG BCBTTGBGCB TGTCGGCGCG GTCCCGTTBB GBGTGGGCCC GCCAGCCCAG CCACTCCACT TGGGGGCGGG TGGCCAGCAC GAACAGCACC CAGAGGAAGG GGGGCGGCCC AGAAGGGCAG CCCGCAGGCC AGGATCAGGT CTGCTGCGGC CGGAGATAAT GGCATTCACC ACGCGGCGGC CCAGCGCACG CCGCGCATCC GGCCCGGGTT CTGACCTGCA GCCCCCGTCT CCTTGGCATT CCTGGGCCCC AGTCACTCCT CTCCCTGCCC CCCTTGCTGG GGCAGGGACG GCCGTGTTGT CBGTGGTGCT GCCCGTTTGB

GGTBTGGCGC TCCBCCBBTT CCCTTTTCTC CTTGTTTTCC GTTTCTCTTG CCGTCTGTGG TT CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG TCTCCGGTAA AACACCGGAG ACTAATTCCT GCCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC AGGAGTGGAG GAGGCCTGGG GGGAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC TCCGTCCCTG CCCCAGCAAG ACAACTTAGA TCTCCAGGAG AACTGCCATC CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT

CTTTAATCTA TTCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGAGGTC TGTGCCAAAG AAGAATCCAA TAAGCACATA TTGAGCACTT GCTGTATATG CAGTATTGAG CACTGTAGGC AAGACCCAAG AAAGAGAAGG AGCCATCTCC ATCTTGAAGG AACTCAAAGA CTCAAGTGGG AACGACTGGG CACTGCCACC ACCAGAAAGC TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC ACAACCACCT GTCCCTGCCT CAGTTCCCTT TTATGTAACA TGAAGTCGTT GTGAGGGTTA AAGGCAGTAA CAGGTATAAA GTACTTAGAA AAGCAAAGGG TGCTACGTAC ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT

ACTATAAGGA AAAGACACTG AGGTCTAGAA ATAGCTCCGT GGAGCAGAAT CAGTATTGGG AGCCGGTGGC GGTGTGAAGC ACCAGTGTCT GGCACACAGT AGGTGCTCAT TGGCTCCCTT CCACCTGTCA TTCCCACCAC CCTGAGGCCC CAACCGCCAC ACACACAGGA GCATTTGGAG AGAAGGCCAT GTCTTCAAAG TCTGATTTGT GATGAGGCAG AGGAAGATAT TTCTAATCGG TCTTGCCCAG AGGATCACAG TGCTGAGACC CCCCACCACC AGCCGGTACC TGGGAAGGGG GAGAGTGCAG GCCTGCTCAG GGACTGTTCC TGTCTCAGCA ACCAAGGGAT TGTTCCTGTC AATCAATGGT TTATTGGAAG GTGGCCCAGT ATGAGCCCTA GAAGAGTGTG AAAAGGAATG GCAATGGTGT TCACCATCGG CAGTGCCAGG GCAGCACTCA TTCACTTGAT AAATGAATAT TTATTAGCTG GTTGGAGAGC TAGAACCTGG AGAGCTAGAA CCTGGAGAAC

TAGAACCTGG AGGGCTAGAA CCTGGAGAGG CTAGAACCAA GAAGGGCTAG AACCTGGAGG GGCTAGAACC TAGAGAAGCT AAAACCTGAG CTAGAAGCTG GAGGACTAGA ACCTGGAGGG CTGGAATCTG AAGGGCTAGA ACCTGGAGGG CTGGAATCTG GAGAGCTAGA ACCTGGAGGG CTAGAACCTG GAGGGCTAGA ACCTAGAAGG GCTAGAACCT GGAGGGCTGG AATCTGGAGA GCTAGAACCT GGAGGGCTAG AACCTGGAGG GCTAGAACCT AGAAGGGCTA GAACCTGGAG GGCTAGAACC TGGCAGGTTA GAACCTAGAA GGGCTAGAAC CTGGAGAGCC AGAACCTGGA GGGCTAGAAC CTGGAAGGGC TAGAACCTGT AGAGCTAGAA CATGGAGAGC TAGAACCCGG CAGGCTAGAA CCTGGCAAGC TAGAACCTGG AGGGAATGAA CCTGGAGGGC TAGAACCTGG AGAATGAGAA AAATTTACAT

GGCAAAGAGC CCATAAATCC TGACCAATCC AACTCTGAAT TTTAAAGCAA AAGCGTGAAA AAAAAGATTC CCTCCTTACC CCCAACCCAC TCTTTTTTCC CACCACCCAC TCTCCTCTGC CTCAGTAAGT ATCTGGAGGA AGAAAACAGG TGAAAGAAGA AGTAAAAACC ATTTAGTATT AGTATTAGAA TGAAGTCAAA CTGTGCCACA CATGGTGAAT GAAAAAAAAA AAAAAGAGGC TGTGTTTTGT CACACAGGGC AGTCATTCAG CACCAGAGCA CGTGATGGTC TGAGACTCTC TTAGGAGCAG AGCTCTGCCG CAATGGCCAT GTGGGGATCC ACACCTGGTG TGAGGGGCAA CTGAGTCTGC GGGAGAAGAG CGGCCCTATG CATGGTGTAG ATGCCCTGAT AAAGAACATC TGTCCTGTGA AAGACTCAAT GAGCTGTTAT GTTGTAAACA GGAAGCATTT CACATCCAAA CGAGAAAATC ATGTAAACAT GTGTCTTTTC TGTAGAGCAT AATAAATGGA TGAGGTTTTT GCAAAAAAAA

AAAAAAAAA AAATGATAGA CCGTCAATAA TTTGTTAAAT GCTTTTTAAA ATGAATGCTT TAAGCCGGGT GCAGTGCCTC ACATCTGTAA TCCCAGCACT TTGGAGCCGA GCGGGTGGAT TGTGTGAGGT CAGGAGTTCG AGACCAACCT GGCCAACATG GCAAAACCTC ACTCTCTACC AAAAATACAA AAATTAGCCA GGCATGGTGG CAGGCACCTG TGATCCCAGC TACTCAGGAG GCTGAGACAG GAGAATCGCT TGAACCCGGG AGGCAAGGTT GCAGTGAGCC AAGATTACGC CATTGTACTC CAGCCTGGGT GACAGAGAGA GACTCCGTCT CAAAAAAAAA AAAAAAAAAA AAAAAATTAC GCTTCAAACA CATGATCTCT CACCACTGTT GAATTTTCTT TCTATGAGCC CAGGAGGGCC TCTCAGAGAG GAAAGCTCCT AGGTCTTCCT TTCCCTCTGC AAACTCCCTG CCTTGAAGGT TCAGAAGGAC TGTGCGTGCT CGTTGCATCC TTTGCAAGTG TCCAAACCCT

GATCCCAGCT GTGCTTAGGG GTTCCTGCAA ACCTTTTCCA GGTGTTAATT ACCTCCCACT TCATTTCCTG TTTACCAACT CAGCTTTTTG TTTTAGTGTG TTTGAATTCC CTGAACTGAC CGTTGTCTGA TCTCCACCTC CCAACTGAAT TAGGGGAGCT GGGCTTCTGG AAACCCAGGT GCCGGGTGTT GCAGAGTGGC TGAAAGCTGG GATGTGGCAG ATCCGTGGCT ACATTCATGC ACACACACAC ACCCACATAC CCACACATGC ACACACACAC ACACACCCGC ACTCACACAC TTGGACATGC ATAGACCACA GCTTTCCACA CCCTTCCTAG ACAGGGGTCA CTTGGTATCC TGGAGAGAGT GTGAAGTCCT GGAATGGAAA GAGGGGGGAT TAAGCCCCAC CTCTAGCCAT GGGACTGAGA CAAGTCACCA CCAACCCATC TGCGCCTTGT TTACCTCCTC TGTGAGGCAA GCACAGAGCC CATGCCTGCC CCCCTGGATG GGAGTGATGT GAAACTTGAA GGGCGGTCAG AGCAAGGGTC

GGGAATGGAA GGCCCTTGGG AAAAAAGGCC CTTTCAACTA GGGGCACAGA GGAGGCCCTG GGCTGAGAAC TTGACAGCAC CTTGTAATTG GTAAGCCAAG CCCGAAGGGA CTGGAAATAC TCAGATGTGT CTGTCTCCCT TATTAGGTTC AAAGTCCCTC AAGACCCTGT CTCCATCACA GTGCTCCAGT CCAGACCCCT CCTCTGAGCT CCAGACCCTG CTGGACCCAA CCAGCCCTAT GGGGTCGCAT CCCCACCTGC CTGGAATTCT CCAAAGAACC TCCCCTTTAA CAGTTCCAGC CTTTAACAGT TCCAGTCTAA ACACATGACC TTTCTCCTCT AAATCAGCCC CCCATCTCTG CCTTTGCAGG AGATGGAAGC CATGACACCT GCCTCGCCCC TGTCCTCACC CCATCCATGT CCAATCAAGC ACTAGGCATG TCAGGTTTAC CCTCTAAACT CCTCTGGAAT CCAGTCTCTC AGTCTCCATC ATCCCAGGTC GAAGCTAATG GGCTAACTGG TCCTTGCTTC CACTCTACCC

CCACTGCAGT CCTGACTTCC TGAGCAGCAG CCAGGGCCTA ATCGATATTC ACACCAAGCG CCAACCTGAC TGAGATATCC TCCTGCACCA TCATCCCTCC ACCCTGTTTA GTTCTGCTCA CCCTCAGTGT TCTCATCAAT AATCCACTCC CCTCACAGGC GCGTTTGGGA CCCCATGTTC TATGCTCTCA CAGGACCTTT TGCTTGATTT TTCACTGTAC TTAGGTCAGT TTGCAGTTAT TAAGTGACTG AGCAATGTCT GGCTTCTCCA GTAGACTGTC AGCTCCTAGC CATTGTATAC CTAGCACCGC TGTGTGGGAG CACGTGACAA ACGTCCAGTG AGTCAGGGAC TCAGCAGTCT CCATTTCTCC GCCCTGCTGG AGAATGCGTG TATTTGGCAA TCCCCAGCCC CTGTGCCATC TAACCATCTT TTCTTCTCTG TTCAGCCCAG GTGTGGCCTC ACTCACATCC CACTCTGAGT CCAAATGTTC TCTCCCTGGA AGATATCAAT GTTTCTGTCT GTTCGTGAGG ACTCCGTGCC CACCACGGCC TCTTTCAGGT GAGTCAAAGG GATTCCTCAG TTCACTAGTT AGGGGAGGTG GGCAGACACC CTGGAGAACT CCCTGGAAAG CTCAACTCTC ATGCCCCGGA CAACAGTTGA AGGAACCATG GTGATGTTAA GCCCAAAGAC AAAACCTCTC AGGTGTCCAA GTCCCTGTTG GAATCTTGGG AGCAGAGGGA ATGTTCTGTG GTCTAGAGGA AGAGGGGCTC AGGGAGGAGA AGGGCACATT CCTGGTTGTT ATATGTTTCT ATCTATCCCA GATGAACTTG GAAGTGAAGG GAAGAGAGTT AAACATTAAA GTAAATACCC AGTGGATCAG ACAGCAATGT GCCAGATTGC CTTGGAAACA AAATATCTCC AACACATGGC TGACATTTGG TGGGAGATCA GAACACCCTA AAGAGAGAAT TTAAGGGGAG

GGGGAGGAGG ACCTGAGCCA GAGTAGAAGC AGAGGATAGG GAGATCTGTT CTTGGGGACA GCATTTGCAA GAAACAAGGC TGAGGGGTCC ACTCCAACCT CTCCACCCTG CTGCAGGTGC TGCCTATGAT GAAGATGAGC AGATGGCCAT CTCAGCTGGG GCCACAGTGC ACTGGACCTA TAGTTTCCAA TTCCGCACTC AGCAGGCATC TTTCTGATGA TCCGATGGCT TCTCAGAGCC AGGGATGGGC CAGGATCCAT CCCCTTGGCT ACTGTCTTGC TGAGAAATTT ATAAGCAGCA TCTGGTGCTA TACTTTGGTC TCTAGTGAGT TAGCTCATGA AAGATGATAG ACTCTCCAAG CCAGGGGTAT GCAGGAAATG GGTTTTCTGT AGCTACAGAA ATGGGGTTGA GGGTTGGACC AAGGGACTAC CCAGGGGAAG TCTTACCTTC AGAGGACTCT GGAAAGGAGG CTGCAAGTTT TCATGGGTCA AGAATTCAGA GCCCAGTAGA GACAGCTTAT CTCTGTTCCA AGATGTCTGG

GGCCTTGGTT GGAAGATTCA AAGGCTAGGA AACCAGGAGC CACCAAAAGC GTAACTGGGG CCAGAGGATC CACTTTCAAG GTGGCAAGTT GGTTCCCCCC ATGTGGCTGC TTGAGTATCC TCACATGGCG GCTCACATCC TTCCAAGTAA GCAATGCAAA AGGCCAAGAA AGATGCTGCA AAGATGTTAT GACCTAGCCT CAGAAATCAC ACACCATCCC TGCCACCATT AGTAAGAAGT CCAGCCCACG TCCAGGAGAA GAGGAAGCAG ATTCCTCCTT TTGAAATGAA GAATATCAAG TAATTCGGGG GGCATATGAA AGCCACCACA CACCACAGGG ATCTTTTTAG AGCATACTTC TTATACCATC ACTGTAGTTC CTTAAGACTC AGGGGCAAAG CCTCACTTCC TTAGCACCCA GTGAAGACCA CGCTTACTCC CTCACTCAAC CTCTTGCTAC TTCCCACCTC TCCTGTCCAA CATCTAGTGT CACTTTCCAG AACATACCAA CAGCTTCCCC AGTTCTGTGC CTCTGCTCAG GCTGTTCCCC

CTGCCTGGTC CACTTGTCCT CCTTCTTGTC CGGTCAAAAT GCTTCTTATC CTTCAAGACC CAGCTCTAGA GTCACCTCCA ACCCCTTACC CACCAGCCCC CTCTCCAAGT CTGTGTCCCA CAACCCCCCT GCTCCCTCCA GGGCACCCTC CACCCTCTGG GCCACAGTTG TCAGGAGTCA GGCAGGGCAG GGGCCGGGTG GTGTCTTCTT TGTGTTCTTG CACTCAGGGC AGAGCTCAGC ACAGAGCAGA CGCTCAAAAA ACATTTAAAG GATAGAAGCA TTGATTTGTG GGTCCCCCAG TCTGGCTCCA GGATGCCAGC CAGCTGCTCC TAGAAGCAAA CGGACTTTTC CTGGGAAATC CCAGAGGTGA TGATCAGTAA TCTCTCCCGT GACTCGTAGT TCAGCTCTTC CTCCATGAGC CTGACTATCA GTGGACCTTC CAGAAAGAGC CCCTTTTCCT TCTCTGACCC ACAGCACAGG GCACTGOGAA AATGCCCAAT GAGTCCTGCC TCTGGGTTGT GCTTTGGACT TTTCAGTGTG TCTCGCATCC

ACTCTTCAAC TTGAATGTTG CAACAGCCAT GAAAAAAGAA ATGCAAAGCG ATTCAGGATG AGAGCAATAC CCTACTCCAA AGAAGGCAAC ATAGAAGCTC AGAGAGATCA AGCAATTTGC CCAAGACCAC ACAGCTAGGA GTGGAACTCA TGGCTGTCCA AGCCCCATGC CTCTGCTGAA GGTAGAGATG AATTACAGCA ACAAGTCTAG AAAGGTGCCT GCCCTATGGT CTGTGAGTCT TGCCTAAGAA TGAAAGAGGA GCCAGTGGGT TAAAGATGAG GTCACCAACA ACGGTGGTGT TGGAGTTTAC CACTGATAAT AAGGGTGCAA AATGTAAATT ACTAATGTTT ATTGAGCCTA GTGCAGTGCG TGGGGCATTT TGCACATTGT CTCTGATCCC TATGACAACC CTGAGAGGTA GTGGTTTTAA CTGCCATGTT ACAGGTGAGG TCATTGTGGT TCAAGGACGT TAAGTAACTT CCCCAGCGTG ACACGGCTTA TAAGTAAGGC AGCCAGGATG TGAACCCAGT AGGACTATCT GGCTGCAAAG

TCCCCACCCC CCTCGGCATC TGTATCCTCC AATCACTTCA GTGCTTTGCT GCATAGAAGG TAACGGAAAT CACGATGCCA CAGACTGTCC AGGAAGACAG AAACTAGGCA GATGGGCTGG CCATGGTCTC CAAGCCAGAC TGGAATCTCC AGGTCTGGAA TGATATCATT TTTCTCTTTT AATAAATTAA CTCACCCACC ACACGGCTTT GAGAGGCTCA AAGTTGACCA ACTCCCTTGG GAGGGCCCCG GTTGATAAGG AAGGAACGTG AATCCTCCCA TCACGGAAGC TTCAAGGAGG TCAAGGGTCC AACACTTGAG ATTGTTAGTG CTGTTGGTGG ATACTGGCCA AGGAAATATC CCAGTGGAGC CTCGAGATGA AGAACATGAG GCCCCCGTTT AGAACCAAGG ATCAGAGGGG GCTCTGTAAG ACCCAGGGGA GTCAGGTGCA CTGGAGCGCG GGCATGCAGA AAACAGCCTG AGCTCCACCT CGGCTTCTCC TTGTCCTGGC TGGTTGTCCT TAACCCCTGT CTCCTTCTGG

ACCAGTTTTT GTCCTTCCCT TGTGACCGCT GAGGGGTAAC AGCCTCTTTC CACTTTCTTT CAGCGCCGAC ATGCTCAATG TCACCTTGCA AGGGCCCACT CTTAACGGGA CCTTTGCCCA GAGCAAATGC CCCCAAGTGG AGTGGCTGGG CTGGCTCAAC ACCATCCAGC CCCCCTTCCT CTGGGTGCTG TTCGTGCTGG CCACCCTAGA GAACATCTTT GTCCTCAGCG TCTTCTGCCT GCACAAGAGC AGCTGCACGG TGGCAGAGAT CTACCTGGGG AACCTGGCCG CAGCAGACCT GATCCTGGCC TGCGGGCTGC CCTTCTGGGC CATCACCATC TCCAACAACT TCGACTGGCT CTTTGGGGAG ACGCTCTGCC GCGTGGTGAA TGCCATTATC TCCATGAACC TGTACAGCAG CATCTGTTTC CTGATGCTGG TGAGCATCGA CCGCTACCTG GCCCTGGTGA AAACCATGTC CATGGGCCGG ATGCGCGGCG TGCGCTGGGC CAAGCTCTAC AGCTTGGTGA TCTGGGGGTG TACGCTGCTC

CTGAGCTCAC CCATGCTGGT GTTCCGGACC ATGAAGGAGT ACAGCGATGA GGGCCACAAC GTCACCGCTT GTGTCATCAG CTACCCATCC GTCATCTGGG AAGTGTTCAC CAACATGCTC CTGAATGTCG TGGGCTTCCT GCTGCCCCTG AGTGTCATCA CCTTCTGCAC GATGCAGATC ATGCAGGTGC TGCGGAACAA CGAGATGCAG AAGTTCAAGG AGATCCAGAC GGAGAGGAGG GCCACGGTGC TAGTCCTGGT TGTGCTGCTG CTATTCATCA TCTGCTGGCT GCCCTTCCAG ATCAGCACCT TCCTGGATAC GCTGCATCGC CTCGGCATCC TCTCCAGCTG CCAGGACGAG CGCATCATCG ATGTAATCAC ACAGATCGCC TCCTTCATGG CCTACAGCAA CAGCTGCCTC AACCCACTGG TGTACGTGAT CGTGGGCAAG CGCTTCCGAA AGAAGTCTTG GGAGGTGTAC CAGGGAGTGT GCCAGAAAGG GGGCTGCAGG TGAGAACCCA TTCAGATGGA GAACTCCATG

GGCACACTGC GGACCTCCAT CTCCGTGGAA CGCCAGATTC ACAAACTGCA GGACTGGGCA GGGAGCAGAC AGTGAGCAAA CGCCAGCAGG GCTGCTGTGA ATTTGTGTAA GGATTGAGGG ACAGTTGCTT TTCAGCATGG GCCCAGGAAT GCCAAGGAGA CATCTATGCA CGACCTTGGG AAATGAGTTG ATGTCTCCGG TAAAACACCG GAGACTAATT CCTGGCCTGC CCAATTTTGC AGGGAGCATG GCTGTGAGGA TGGGGTGAAC TCACGCACAG CCAAGGACTC CAAAATCACA ACAGCATTAC TGTTCTTATT TGCTGCCACA CCTGAGCCAG CCTGCTCCTT CCCAGGAGTG GAGGAGGCCT GGGGGCAGGG AGAGGAGTGA CTGAGCTTCC CTCCCGTGTG TTCTCCGTCC CTGCCCCAGC AAGACAACTT AGATCTCCAG GAGAACTGCC ATCCAGCTTT GGTGCAATGG CTGAGTGCAC AAGTGAGTTG TTGCCCTGGG TTTCTTTAAT CTATTCAGCT AGAACTTTGA

AGGACAATTT CTTGCATTAA TAAAGGTTAA GCCCTGAGGG GTCCCTGATA ACAACCTGGA GACCAGGATT TTATGGCTCC CCTCACTGAT GGACAAGGAG GTCTGTGCCA AAGAAGAATC CAATAAGCAC ATATTGAGCA CTTGCTGTAT ATGCAGTATT GAGCACTGTA GGCAAGAGGG AAGAAAGAGA AGGAGCCATC TCCATCTTGA AGGAACTCAA AGACTCAAGT GGGAACGACT GGGCACTGCC ACCACCAGAA AGCTGTTCGA TGAGACGGTC GAGCAGGGTG CTGTGGGTGA TATGGACAGC AGAAGGGGGA GCCAGGTTCC AGCTCACCAA TACTATTGCA CACCACCTGT CCTGCCTC GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG GCTCCGAGGA GGGGTGGGGA CGGTGGTGAC GGTGGGGACA TCAGGCTGCC CCGCAGTACC AGGGAGCGAC TGAAGTGCCC ATGCCGCTTG CTCCGGAGAA GGTGGGTGCC

GGGCAGGGGC TGCTCCAGCC GCCTCACCTC TGCTGGGAGG ACAAACTGTC CCAGCACAGA GGGAGGGAGG GAGGGCAGGC AGCGGGGAGA AGTTTCCCTG TGGTCGTGGG GAGTT GAGCTCTTCA ATATTTTAGT GAAAGCTATA GATGAGGCTC CATAGGGGAT AAAGCACAGA CACACCTTTT CAGAGGGCTT GTGGACTCTG GGCAGCCTGT CCATAGACCT CTGTCCCCAA CTGGCAAGTC AGGAAACTCC AGATTAAGGA GCCCCAATGT GGTTGAACAG CCAGGTGCAC AGATGAGTCA ACCACACAGC CAGGCCAGGG AGGGCCTTCA CTCAAGAGCC TACAGCCAGT TCACAGCCAA GCCAGGGCTA GCGCCAGGCC ACCCATAAAC TGATCTGAGA CTCTGTTTCC CTGTCTCCAT GATGATGGGA TCAGGCTTGA TTGCTGGTTT GTAGGCTTGT TATGAATCAA GTCACAGGGA AGAGGAGCTG ATGGGCTGGG GGGACGTCCT CTGGCCCTCC TGTCTCTTCC

CCAGATCCAC TGGGCCCACT CTTATCTGTT CTCTTCTGAA GGAAGGGTTT TAAGGCTTCA AAAAAAAATG TTTTGAAAGT CCCTGCCCTT TCCAGCTCCT ACCGTCTCAG CCCTGGGAGT GTAAAGTGCT GCAGATAGTT AGTAAGTCTT TGAGCAAAAC TGAGAAAGCC AGCCTGAGCC TTGACATGGG AGAAACCTCC GCCATACATC TCCGAAGAAA CGGCCGCGTG TCTCAGGGGA GCGCAAACAC CCGTACCCAG GAAACAGGAC AGCTTCTGCC ACTGTCGCCC TTGGGAGCCG TACGTGGCAT GACAAAGAAA TCCCAGGACT CCGCCTGCCC ACCTGGCCAC CCTCTGTTTA CACCTTCCGC GTAAACGCCC ACTGTTTACA TCCAAAACTC AGACACAAAA TAACCACCTC AAGAAGATAA ATAATGATAA GAAATAAATG TTACGCGAGG CAAATTTATT CACATGGGGC TTCCCAGGCC ACTTTGTGGT CAGCCGGGAG GGACGTTTTT GCCGTCCCAC GACTCCAACG GGCAGCCGGG

CCTACGCAAA CATGGAAATC TTCCAAGAGC CTCCCTGGCC CCCAGGGCTC AGAGGGTGGC AGAGCGGAGA GCGAAGGTGG CCGCAGCCTT CCCGGCCCCA CAGCCAGCCT GGCTCCAGCT GGGCAGGAGT GCAGAGCTCA GCTGGAGGCG AGGGGGAAGT GCCCAGGAGG CTGATGACAT CACTACCCAG CCCTTCAAAG ATGAGCTGTT CCCGCCGCCA CTCCAGCTCT GGCTTCTGGG CTCCGAGGAG GGGTGGGGAC GGTGGTGACG GTGGGGACAT CAGGCTGCCC CGCAGTACCA GGGAGCGACT GAAGTGCCCA TGCCGCTTGC TCCGGAGAAG GTGGGTGCCG GGCAGGGGCT GCTCCAGCCG CCTCACCTCT GCTGGGAGGA CAAACTGTCC CAGCACAGAG GGAGGGAGGG AGGGCAGGCA GCGGOGAGAA GTTTCCCTGT GGTCGTGGGG AGTTGGGAAA AGTTCCCTTC CTTCCGGAGG GAGG CAGATTCACA AACTGCAGGA

CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG TCTCCGGTAA AACACCGGAG ACTAATTCCT GCCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC AGGAGTGGAG GAGGCCTGGG GGGAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC TCCGTCCCTG CCCCAGCAAG ACAACTTAGA TCTCCAGGAG AACTGCCATC CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT CTTTAATCTA TTCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA

ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGAGGTC TGTGCCAAAG AAGAATCCAA TAAGCACATA TTGAGCACTT GCTGTATATG CAGTATTGAG CACTGTAGGC AAGACCCAAG AAAGAGAAGG AGCCATCTCC ATCTTGAAGG AACTCAAAGA CTCAAGTGGG AACGACTGGG CACTGCCACC ACCAGAAAGC TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC ACAACCACCT GTCCCTGCCT CAGTTCCCTT TTATGTAACA TGAAGTCGTT GTGAGGGTTA AAGGCAGTAA CAGGTATAAA GTACTTAGAA AAGCAAAGGG TGCTACGTAC ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT ACTATAAGGA AAAGACACTG AGGTCTAGAA ATAGCTCCGT GGAGCAGAAT CAGTATTGGG AGCCGGTGGC GGTGTGAAGC ACCAGTGTCT

GGCACACAGT AGGTGCTCAT TGGCTCCCTT CCACCTGTCA TTCCCACCAC CCTGAGGCCC CAACCGCCAC ACACACAGGA GCATTTGGAG AGAAGGCCAT GTCTTCAAAG TCTGATTTGT GATGAGGCAG AGGAAGATAT TTCTAATCGG TCTTGCCCAG AGGATCACAG TGCTGAGACC CCCCACCACC AGCCGGTACC TGGGAAGGGG GAGAGTGCAG GCCTGCTCAG GGACTGTTCC TGTCTCAGCA ACCAAGGGAT TGTTCCTGTC AATCAATGGT TTATTGGAAG GTGGCCCAGT ATGAGCCCTA GAAGAGTGTG AAAAGGAATG GCAATGGTGT TCACCATCGG CAGTGCCAGG GCAGCACTCA TTCACTTGAT AAATGAATAT TTATTAGCTG GTTGGAGAGC TAGAACCTGG AGAGCTAGAA CCTGGAGAAC TAGAACCTGG AGGGCTAGAA CCTGGAGAGG CTAGAACCAA GAAGGGCTAG AACCTGGAGG GGCTAGAACC TAGAGAAGCT AAAACCTGAG CTAGAAGCTG

GAGGACTAGA ACCTGGAGGG CTGGAATCTG AAGGGCTAGA ACCTGGAGGG CTGGAATCTG GAGAGCTAGA ACCTGGAGGG CTAGAACCTG GAGGGCTAGA ACCTAGAAGG GCTAGAACCT GGAGGGCTGG AATCTGGAGA GCTAGAACCT GGAGGGCTAG AACCTGGAGG GCTAGAACCT AGAAGGGCTA GAACCTGGAG GGCTAGAACC TGGCAGGTTA GAACCTAGAA GGGCTAGAAC CTGGAGAGCC AGAACCTGGA GGGCTAGAAC CTGGAAGGGC TAGAACCTGT AGAGCTAGAA CATGGAGAGC TAGAACCCGG CAGGCTAGAA CCTGGCAAGC TAGAACCTGG AGGGAATGAA CCTGGAGGGC TAGAACCTGG AGAATGAGAA AAATTTACAT GGCAAAGAGC CCATAAATCC TGACCAATCC AACTCTGAAT TTTAAAGCAA AAGCGTGAAA AAAAAGATTC CCTCCTTACC CCCAACCCAC TCTTTTTTCC CACCACCCAC

TCTCCTCTGC CTCAGTAAGT ATCTGGAGGA AGAAAACAGG TGAAAGAAGA AGTAAAAACC ATTTAGTATT AGTATTAGAA TGAAGTCAAA CTGTGCCACA CATGGTGAAT GAAAAAAAAA AAAAAGAGGC TGTGTTTTGT CACACAGGGC AGTCATTCAG CACCAGAGCA CGTGATGGTC TGAGACTCTC TTAGGAGCAG AGCTCTGCCG CAATGGCCAT GTGGGGATCC ACACCTGGTC TGAGGGGCAA CTGAGTCTGC GGGAGAAGAG CGGCCCTATG CATGGTGTAG ATGCCCTGAT AAAGAACATC TGTCCTGTGA AAGACTCAAT GAGCTGTTAT GTTGTAAACA GGAAGCATTT CACATCCAAA CGAGAAAATC ATGTAAACAT GTGTCTTTTC TGTAGAGCAT AATAAATGGA TGAGGTTTTT GCAAAAAAAA AAAAAAAAA AAATGATAGA CCGTCAATAA TTTGTTAAAT GCTTTTTAAA ATGAATGCTT TAAGCCGGGT GCAGTGCCTC ACATCTGTAA TCCCAGCACT TTGGAGCCGA

GCGGGTGGAT TGTGTGAGGT CAGGAGTTCG AGACCAACCT GGCCAACATG GCAAAACCTC ACTCTCTACC AAAAATACAA AAATTAGCCA GGCATGGTGG CAGGCACCTG TGATCCCAGC TACTCAGGAG GCTGAGACAG GAGAATCGCT TGAACCCGGG AGGCAAGGTT GCAGTGAGCC AAGATTACGC CATTGTACTC CAGCCTGGGT GACAGAGAGA GACTCCGTCT CAAAAAAAAA AAAAAAAAAA AAAAAATTAC GCTTCAAACA CATGATCTCT CACCACTGTT GAATTTTCTT TCTATGAGCC CAGGAGGGCC TCTCAGAGAG GAAAGCTCCT AGGTCTTCCT TTCCCTCTGC AAACTCCCTG CCTTGAAGGT TCAGAAGGAC TGTGCGTGCT CGTTGCATCC TTTGCAAGTG TCCAAACCCT GATCCCAGCT GTGCTTAGGG GTTCCTGCAA ACCTTTTCCA GGTGTTAATT ACCTCCCACT TCATTTCCTG TTTACCAACT CAGCTTTTTG TTTTAGTGTG TTTGAATTCC

CTGAACTGAC CGTTGTCTGA TCTCCACCTC CCAACTGAAT TAGGGGAGCT GGGCTTCTGG AAACCCAGGT GCCGGGTGTT GCAGAGTGGC TGAAAGCTGG GATGTGGCAG ATCCGTGGCT ACATTCATGC ACACACACAC ACCCACATAC CCACACATGC ACACACACAC ACACACCCGC ACTCACACAC TTGGACATGC ATAGACCACA GCTTTCCACA CCCTTCCTAG ACAGGGGTCA CTTGGTATCC TGGAGAGAGT GTGAAGTCCT GGAATGGAAA GAGGGGGGAT TAAGCCCCAC CTCTAGCCAT GGGACTGAGA CAAGTCACCA CCAACCCATC TGCGCCTTGT TTACCTCCTC TGTGAGGCAA GCACAGAGCC CATGCCTGCC CCCCTGGATG GGAGTGATGT GAAACTTGAA GGGCGGTCAG AGCAAGGGTC GGGAATGGAA GGCCCTTGGG AAAAAAGGCC CTTTCAACTA GGGGCACAGA GGAGGCCCTG GGCTGAGAAC TTGACAGCAC CTTGTAATTG GTAAGCCAAG CCCGAAGGGA CTGGAAATAC TCAGATGTGT CTGTCTCCCT TATTAGGTTC AAAGTCCCTC AAGACCCTGT CTCCATCACA GTGCTCCAGT CCAGACCCCT CCTCTGAGCT CCAGACCCTG CTGGACCCAA CCAGCCCTAT GGGGTCGCAT CCCCACCTGC CTGGAATTCT CCAAAGAACC TCCCCTTTAA CAGTTCCAGC CTTTAACAGT TCCAGTCTAA ACACATGACC TTTCTCCTCT AAATCAGCCC CCCATCTCTG CCTTTGCAGG AGATGGAAGC CATGACACCT GCCTCGCCCC TGTCCTCACC CCATCCATGT CCAATCAAGC ACTAGGCATG TCAGGTTTAC CCTCTAAACT CCTCTGGAAT CCAGTCTCTC AGTCTCCATC ATCCCAGGTC GAAGCTAATG GGCTAACTGG TCCTTGCTTC CACTCTACCC

CCACTGCAGT CCTGACTTCC TGAGCAGCAG CCAGGGCCTA ATCGATATTC ACACCAAGCG CCAACCTGAC TGAGATATCC TCCTGCACCA TCATCCCTCC ACCCTGTTTA GTTCTGCTCA CCCTCAGTGT TCTCATCAAT AATCCACTCC CCTCACAGGC GCGTTTGGGA CCCCATGTTC TATGCTCTCA CAGGACCTTT TGCTTGATTT TTCACTGTAC TTAGGTCAGT TTGCAGTTAT TAAGTGACTG AGCAATGTCT GGCTTCTCCA GTAGACTGTC AGCTCCTAGC CATTGTATAC CTAGCACCGC TGTGTGGGAG CACGTGACAA ACGTCCAGTG AGTCAGGGAC TCAGCAGTCT CCATTTCTCC GCCCTGCTGG AGAATGCGTG TATTTGGCAA TCCCCAGCCG CTGTGCCATC TAACCATCTT TTCTTCTCTG TTCAGCCCAG GTGTGGCCTC ACTCACATCC CACTCTGAGT CCAAATGTTC TCTCCCTGGA AGATATCAAT GTTTCTGTCT GTTCGTGAGG ACTCCGTGCC CACCACGGCC

TCTTTCAGGT GAGTCAAAGG GATTCCTCAG TTCACTAGTT AGGGGAGGTG GGCAGACACC CTGGAGAACT CCCTGGAAAG CTCAACTCTC ATGCCCCGGA CAACAGTTGA AGGAACCATG GTGATGTTAA GCCCAAAGAC AAAACCTCTC AGGTGTCCAA GTCCCTGTTG GAATCTTGGG AGCAGAGGGA ATGTTCTGTG GTCTAGAGGA AGAGGGGCTC AGGGAGGAGA AGGGCACATT CCTGGTTGTT ATATGTTTCT ATCTATCCCA GATGAACTTG GAAGTGAAGG GAAGAGAGTT AAACATTAAA GTAAATACCC AGTGGATCAG ACAGCAATGT GCCAGATTGC CTTGGAAACA AAATATCTCC AACACATGGC TGACATTTGG TGGGAGATCA GAACACCCTA AAGAGAGAAT TTAAGGGGAG GGGGAGGAGG ACCTGAGCCA GAGTAGAAGC AGAGGATAGG GAGATCTGTT CTTGGGGACA GCATTTGCAA GAAACAAGGC TGAGGGGTCC ACTCCAACCT

CTCCACCCTG CTGCAGGTGC TGCCTATGAT GAAGATGAGC AGATGGCCAT CTCAGCTGGG GCCACAGTGC ACTGGACCTA TAGTTTCCAA TTCCGCACTC AGCAGGCATC TTTCTGATGA TCCGATGGCT TCTCAGAGCC AGGGATGGGC CAGGATCCAT CCCCTTGGCT ACTGTCTTGC TGAGAAATTT ATAAGCAGCA TCTGGTGCTA TACTTTGGTC TCTAGTGAGT TAGCTCATGA AAGATGATAG ACTCTCCAAG CCAGGGGTAT GCAGGAAATG GGTTTTCTGT AGCTACAGAA ATGGGGTTGA GGGTTGGACC AAGGGACTAC CCAGGGGAAG TCTTACCTTC AGAGGACTCT GGAAAGGAGG CTGCAAGTTT TCATGGGTCA AGAATTCAGA GCCCAGTAGA GACAGCTTAT CTCTGTTCCA AGATGTCTGG GGCCTTGGTT GGAAGATTCA AAGGCTAGGA AACCAGGAGC CACCAAAAGC GTAACTGGGG CCAGAGGATC CACTTTCAAG GTGGCAAGTT GGTTCCCCCC ATGTGGCTGC

TTGAGTATCC TCACATGGCG GCTCACATCC TTCCAAGTAA GCAATGCAAA AGGCCAAGAA AGATGCTGCA AAGATGTTAT GACCTAGCCT CAGAAATCAC ACACCATCCC TGCCACCATT AGTAAGAAGT CCAGCCCACG TCCAGGAGAA GAGGAAGCAG ATTCCTCCTT TTGAAATGAA GAATATCAAG TAATTCGGGG GGCATATGAA AGCCACCACA CACCACAGGG ATCTTTTTAG AGCATACTTC TTATACCATC ACTGTAGTTC CTTAAGACTC AGGGGCAAAG CCTCACTTCC TTAGCACCCA GTGAAGACCA CGCTTACTCC CTCACTCAAC CTCTTGCTAC TTCCCACCTC TCCTGTCCAA CATCTAGTGT CACTTTCCAG AACATACCAA CAGCTTCCCC AGTTCTGTGC CTCTGCTCAG GCTGTTCCCC CTGCCTGGTC CACTTGTCCT CCTTCTTGTC CGGTCAAAAT GCTTCTTATC CTTCAAGACC CAGCTCTAGA GTCACCTCCA ACCCCTTACC CACCAGCCCC CTCTCCAAGT

CTGTGTCCCA CAACCCCCCT GCTCCCTCCA GGGCACCCTC CACCCTCTGG GCCACAGTTG TCAGGAGTCA GGCAGGGCAG GGGCCGGGTG GTGTCTTCTT TGTGTTCTTG CACTCAGGGC AGAGCTCAGC ACAGAGCAGA CGCTCAAAAA ACATTTAAAG GATAGAAGCA TTGATTTGTG GGTCCCCCAG TCTGGCTCCA GGATGCCAGC CAGCTGCTCC TAGAAGCAAA CGGACTTTTC CTGGGAAATC CCAGAGGTGA TGATCAGTAA TCTCTCCCGT GACTCGTAGT TCAGCTCTTC CTCCATGAGC CTGACTATCA GTGGACCTTC CAGAAAGAGC CCCTTTTCCT TCTCTCACCC ACAGCACAGG GCACTGGGAA AATGCCCAAT GAGTCCTGCC TCTGGGTTGT GCTTTGGACT TTTCAGTGTG TCTCGCATCC ACTCTTCAAC TTGAATGTTG CAACAGCCAT GAAAAAAGAA ATGCAAAGCG ATTCAGGATG AGAGCAATAC CCTACTCCAA AGAAGGCAAC ATAGAAGCTC AGAGAGATCA

AGCAATTTGC CCAAGACCAC ACAGCTAGGA GTGGAACTCA TGGCTGTCCA AGCCCCATGC CTCTGCTGAA GGTAGAGATG AATTACAGCA ACAAGTCTAG AAAGGTGCCT GCCCTATGGT CTGTGAGTCT TGCCTAAGAA TGAAAGAGGA GCCAGTGGGT TAAAGATGAG GTCACCAACA ACGGTGGTGT TGGAGTTTAC CACTGATAAT AAGGGTGCAA AATGTAAATT ACTAATGTTT ATTGAGCCTA GTGCAGTGCG TGGGGCATTT TGCACATTGT CTCTGATCCC TATGACAACC CTGAGAGGTA GTGGTTTTAA CTGCCATGTT ACAGGTGAGG TCATTGTGGT TCAAGGACGT TAAGTAACTT CCCCAGCGTG ACACGGCTTA TAAGTAAGGC AGCCAGGATG TGAACCCAGT AGGACTATCT GGCTGCAAAG TCCCCACCCC CCTCGCCATC TGTATCCTCC AATCACTTCA GTGCTTTGCT GCATAGAAGG TAACGGAAAT CACGATGCCA CAGACTGTCC AGGAAGACAG AAACTAGGCA

GATGGGCTGG CCATGGTCTC CAAGCCAGAC TGGAATCTCC AGGTCTGGAA TGATATCATT TTTCTCTTTT AATAAATTAA CTCACCCACC ACACGGCTTT GAGAGGCTCA AAGTTGACCA ACTCCCTTGG GAGGGCCCCG GTTGATAAGG AAGGAACGTG AATCCTCCCA TCACGGAAGC TTCAAGGAGG TCAAGGGTCC AACACTTGAG ATTGTTAGTG CTGTTGGTGG ATACTGGCCA AGGAAATATC CCAGTGGAGC CTCGAGATGA AGAACATGAG GCCCCCGTTT AGAACCAAGG ATCAGAGGGG GCTCTGTAAG ACCCAGGGGA GTCAGGTGCA CTGGAGCGCG GGCATGCAGA AAACAGCCTG AGCTCCACCT CGGCTTCTCC TTGTCCTGGC TGGTTGTCCT TAACCCCTGT CTCCTTCTGG ACCAGTTTTT GTCCTTCCCT TGTGACCGCT GAGGGGTAAC AGCCTCTTTC CACTTTGTTT CAGCGCCGAC ATGCTCAATG TCACCTTGCA AGGGCCCACT CTTAACGGGA

CCTTTGCCCA GAGCAAATGC CCCCAAGTGG AGTGGCTGGG CTGGCTCAAC ACCATCCAGC CCCCCTTCCT CTGGGTGCTG TTCGTGCTGG CCACCCTAGA GAACATCTTT GTCCTCAGCG TCTTCTGCCT GCACAAGAGC AGCTGCACGG TGGCAGAGAT CTACCTGGGG AACCTGGCCG CAGCAGACCT GATCCTGGCC TGCGGGCTGC CCTTCTGGGC CATCACCATC TCCAACAACT TCGACTGGCT CTTTGGGGAG ACGCTCTGCC GCGTGGTGAA TGCCATTATC TCCATGAACC TGTACAGCAG CATCTGTTTC CTGATGCTGG TGAGCATCGA CCGCTACCTG GCCCTGGTGA AAACCATGTC CATGGGCCGG ATGCGCGGCG TGCGCTGGGC CAAGCTCTAC AGCTTGGTGA TCTGGGGGTG TACGCTGCTC CTGAGCTCAC CCATGCTGGT GTTCCGGACC ATGAAGGAGT ACAGCGATGA GGGCCACAAC GTCACCGCTT GTGTCATCAG CTACCCATCC CTCATCTGGG AAGTGTTCAC

CAACATGCTC CTGAATGTCG TGGGCTTCCT GCTGCCCCTG AGTGTCATCA CCTTCTGCAC GATGCAGATC ATGCAGGTGC TGCGGAACAA CGAGATGCAG AAGTTCAAGG AGATCCAGAC GGAGAGGAGG GCCACGGTGC TAGTCCTGGT TGTGCTGCTG CTATTCATCA TCTGCTGGCT GCCCTTCCAG ATCAGCACCT TCCTGGATAC GCTGCATCGC CTCGGCATCC TCTCCAGCTG CCAGGACGAG CGCATCATCG ATGTAATCAC ACAGATCGCC TCCTTCATGG CCTACAGCAA CAGCTGCCTC AACCCACTGG TGTACGTGAT CGTGGGCAAG CGCTTCCGAA AGAAGTCTTG GGAGGTGTAC CAGGGAGTGT GCCAGAAAGG GGGCTGCAGG TGAGAACCCA TTCAGATGGA GAACTCCATG GGCACACTGC GGACCTCCAT CTCCGTGGAA CGCCAGATTC ACAAACTGCA GGACTGGGCA GGGAGCAGAC AGTGAGCAAA CGCCAGCAGG GCTGCTGTGA

ATTTGTGTAA GGATTGAGGG ACAGTTGCTT TTCAGCATGG GCCCAGGAAT GCCAAGGAGA CATCTATGCA CGACCTTGGG AAATGAGTTG ATGTCTCCGG TAAAACACCG GAGACTAATT CCTGCCCTGC CCAATTTTGC AGGGAGCATG GCTGTGAGGA TGGGGTGAAC TCACGCACAG CCAAGGACTC CAAAATCACA ACAGCATTAC TGTTCTTATT TGCTGCCACA CCTGAGCCAG CCTGCTCCTT CCCAGGAGTG GAGGAGGCCT GGGGGCAGGG AGAGGAGTGA CTGAGCTTCC CTCCCGTGTG TTCTCCGTCC CTGCCCCAGC AAGACAACTT AGATCTCCAG GAGAACTGCC ATCCAGCTTT GGTGCAATGG CTGAGTGCAC AAGTGAGTTG TTGCCCTGGG TTTCTTTAAT CTATTCAGCT AGAACTTTGA AGGACAATTT CTTGCATTAA TAAAGGTTAA GCCCTGAGGG GTCCCTGATA ACAACCTGGA GACCAGGATT TTATGGCTCC CCTCACTGAT GGACAAGGAG GTCTGTGCCA

AAGAAGAATC CAATAAGCAC ATATTGAGCA CTTGCTGTAT ATGCAGTATT GAGCACTGTA GGCAAGAGGG AAGAAAGAGA AGGAOCCATC TCCATCTTGA AGGAACTCAA AGACTCAAGT GGGAACGACT GGGCACTGCC ACCACCAGAA AGCTGTTCGA TGAGACGGTC GAGCAGGGTG CTGTGGGTGA TATGGACAGC AGAAGGGGGA GCCAGGTTCC AGCTCACCAA TACTATTGCA CACCACCTGT CCTGCCTC CTGCAGAAAA CAGCCTGAGC TCCACCTCGG CTTCTCCTTG CCCTGGCTGG TTGTCCTTAA CCCCTGTCTC CTTCTGGACC AGTTTTTGTC CTTCCCTTGT GACCCTGAGG GGTAACAGCC TCTTTTCCAC TTTCTTTCAG CGCCGACATG CTCAATGTCA CCTTGCAAGG GCCCACTCTT AACGGGACCT TTGCCCAGAG CAAATGCCCC CAAGTGGAGT GGCTGGGCTG GCTCAACACC ATCCAGCCCC CCTTCCTCTG GGTGCTGTTC GTGCTGGCCA

CCCTAGAGAA CATCTTTGTC CTCAGCGTCT TCTGCCTGCA CAAGAGCAGC TGCACGGTGG CAGAGATCTA CCTGGGGAAC CTGGCCGCAG CAGACCTGAT CCTGGCCTGC GGGCTGCCCT TCTGGGCCAT CACCATCTCC AACAACTTCG ACTGGCTCTT TGGGGAGACG CTCTGCCGCG TGGTGAATGC CATTATCTCC ATGAACCTGT ACAGCAGCAT CTGTTTCCTG ATGCTGGTGA GCATCGACCG CTACCTGGCC CTGGTGAAAA CCATGTCCAT GGGCCGGATG CGCGGCGTGC GCTGGGCCAA GCTCTACAGC TTGGTGATCT GGGGGTGTAC GCTGCTCCTG AGCTCACCCA TGCTGGTGTT CCGGACCATG AAGGAGTACA GCGATGAGGG CCACAACGTC ACCGCTTGTG TCATCAGCTA CCCATCCCTC ATCTGGGAAG TGTTCACCAA CATGCTCCTG AATGTCGTGG GCTTCCTGCT GCCCCTGAGT GTCATCACCT TCTGCACGAT GCAGATCATG CAGGTGCTGC GGAACAACGA

GATGCAGAAG TTCAAGGAGA TCCAGACGGA GAGGAGGGCC ACGGTGCTAG TCCTGGTTGT GCTGCTGCTA TTCATCATCT GCTGGCTGCC CTTCCAGATC AGCACCTTCC TGGATACGCT GCATCGCCTC GGCATCCTCT CCAGCTGCCA GGACGAGCGC ATCATCGATG TAATCACACA GATCGCCTCC TTCATGGCCT ACAGCAACAG CTGCCTCAAC CCACTGGTGT ACGTGATCGT GGGCAAGCGC TTCCGAAAGA AGTCTTGGGA GGTGTACCAG GGAGTGTGCC AGAAAGGGGG CTGCAGGTCA GAACCCATTC AGATGGAGAA CTCCATGGGC ACACTGCGGA CCTCCATCTC CGTGGAACGC CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG

TCTCCGGTAA AACACCGGAG ACTAATTCCT GNCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC AGGAGTGGAG GAGGCCTGGG GGCAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC TCCGTCCCTG CCCCAGCAAG ACAACTTAGA TCTCCAGGAG AACTGCCATC CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT CTTTAATCTA TTCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGGAGGT CTGTGCCAAA GAAGAATCCA ATAAGCACAT ATTGAGCACT TGCTGTATAT GCAGTATTGA GCACTGTAGG CAAGAGGGAA GAAAGAGAAG

GAGCCATCTC CATCTTGAAG GAACTCAAAG ACTCAAGTGG GAACGACTGG CACTGCCACC ACCAGAAAGC TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC ACAACCACCT GTCCCTGCCT CAGTTCCCTC TTCTGTAACA TGAAGTCGTT GTGAGGGTTA AAGGCAGTAA CAGGTATAAA GTACTTAGAA AAGCAAAGGG TGCTACGTAC ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT ACTATAAGGA AAAGACACTG AGGTCTAGA TGATCCTATC ACAACCTGAG AGTAGTTTTT ACTCCATTTA CAGGTGAGGT CATTGTGGTT CAAGGACGTT AAGTAACTTC CCCAGCTCAC ACGGCTTATA AGTAAGGCAG CCAGGATGTG AACCCAGTAG GACTATCTGG CTGCAAAGTC CCCACCCTCC CTCGCCATCT GTATCCTCCA ATCATCTTCA GTGCTTTGCT GATAGAAGGT

ACGGAAATAC GATGCCACAG ACTGTCCAGG AAGACAGAAA CTAGGCAGAT GGGCTGGCCA TGGTCTCCAA GCCAGACTGG AATCTCCAGG TCTGGAATGA TATCATTTTT CTCTTTTAAT AAATTAACTC ACCCACCACA CGGCTTTGAG AGGCTCAAAG GTGACCAACT CCCTTGGGAG GGCCCCGGTT GATAAGGAAG GAATGTGAAT CCTCCCATCA CGGAAGCTTC AAGGAGGTCA AGGGTCCAAC ACTTGAGATT GTTAGTGCTG TTGGTGGATA CTGCAGAATA TCCAGTGGAG CCTCAGATGA AGAACATGAG GCCCCGTTTA GATCCAAGGA TCAGAGGGGG CTCTGTAAGA CCCAGGGGAG TCAGGTGCAC TGGAGCGCGG GCTGCAGAAA ACAGCCTGAG CTCCACCTCG GCTTCTCCTT GCCCTGGCTG GTTGTCCTTA ACCCCTGTCT CCTTCTGGAC CAGTTTTTGT CCTTCCCTTG TGACCTGAGG GGTAACAGCC TCTTTTCCAC TTTCTTTCAG CGCCGACATG CTCAATGTCA

CCTTGCAAGG GCCCACTCTT AACGGGACCT TTGCCCAGAG CAAATGCCCC CAAGTGGAGT GGCTGGGCTG GCTCAACACC ATCCAGCCCC CCTTCCTCTG GGTGCTGTTC GTGCTGGCCA CCCTAGAGAA CATCTTTGTC CTCAGCGTCT TCTGCCTGCA CAAGAGCAGC TGCACGGTGG CAGAGATCTA CCTGGGGAAC CTGGCCGCAG CAGACCTGAT CCTGGCCTGC GGGCTGCCCT TCTGGGCCAT CACCATCTCC AACAACTTCG ACTGGCTCTT TGGGGAGACG CTCTGCCGCG TGGTGAATGC CATTATCTCC ATGAACCTGT ACAGCAGCAT CTGTTTCCTG ATGCTGGTGA GCATCGACCG CTACCTGGCC CTGGTGAAAA CCATGTCCAT GGGCCGGATG CGCGGCGTGC GCTGGGCCAA GCTCTACAGC TTGGTGATCT GGGGGTGTAC GCTGCTCCTG AGCTCACCCA TGCTGGTGTT CCGGACCATG AAGGAGTACA GCGATGAGGG CCACAACGTC ACCGCTTGTG TCATCAGCTA

CCCATCCCTC ATCTGGGAAG TGTTCACCAA CATGCTCCTG AATGTCGTGG GCTTCCTGCT GCCCCTGAGT GTCATCACCT TCTGCACGAT GCAGATCATG CAGGTGCTGC GGAACAACGA GATGCAGAAG TTCAAGGAGA TCCAGACGGA GAGGAGGGCC ACGGTGCTAG TCCTGGTTGT GCTGCTGCTA TTCATCATCT GCTGGCTGCC CTTCCAGATC AGCACCTTCC TGGATACGCT GCATCGCCTC GGCATCCTCT CCAGCTGCCA GGACGAGCGC ATCATCGATG TAATCACACA GATCGCCTCC TTCATGGCCT ACAGCAACAG CTGCCTCAAC CCACTGGTGT ACGTGATCGT GGGCAAGCGC TTCCGAAAGA AGTCTTGGGA GGTGTACCAG GGAGTGTGCC AGAAAGGGGG CTGCAGGTCA GAACCCATTC AGATGGAGAA CTCCATGGGC ACACTGCGGA CCTCCATCTC CGTGGAACGC CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC

CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTGTTGA TGTCTCCGGT AAAACACCGG AGACTAATTC CTGCCCTGCC CAATTTTCGA GGGAGCATGG CTGTGAGGAT GGGGTGAACT CACGCACAGC CAAGGACTCC AAAATCACAA CAGCATTACT GTTCTTATTT GCTGCCACAC CTGAGCCAGC CTGCTCCTTC CCAGGAGTGG AGGAGGCCTG GGGGAGGGAG AGGAGTGACT GAGCTTCCCT CCCGTGTGTT CTCCGTCCCT GCCCCAGCAA GACAACTTAG ATCTCCAGGA GAACTGCCAT CCACGTTTGG TGCAATGGCT GAGTGCACAA GTGAGTTGTT GCCCTGGGTT TCTTTAATCT ATCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTTGATAAC AACCTGGAGA CCAGGATTTT ATGGCTCCCC TCACTGATGG ACAAGGAGGT CTGTGCCAAA GAAGAATCAA TAAGCACATA TGAGCACTTC TGTATATCAG TATTGAGCAC TGTAGGCA ATGTTCTCTC CCTGGAAGAT ATCAATGTTT CTGTCTGTTT GTGAGGACTC CGTGCCCACC ACGGCCTCTT TCAGCGCCGA CATGCTCAAT GTCACCTTGC AAGGGCCCAC TCTTAACGGG ACCTTTGCCC AGAGCAAATG CCCCCAAGTG GAGTGGCTGG GCTGGCTCAA CACCATCCAG CCCCCCTTCC TCTGGGTGCT GTTCGTGCTG GCCACCCTAG AGAACATCTT TGTCCTCAGC GTCTTCTGCC TGCACAAGAG CAGCTGCACG GTGGCAGAGA TCTACCTGGG GAACCTGGCC GCAGCAGACC TGATCCTGGC CTGCGGGCTG CCCTTCTGGG CCATCACCAT CTCCAACAAC

TTCGACTGGC TCTTTGGGGA GACGCTCTGC CGCGTGGTGA ATGCCATTAT CTCCATGAAC CTGTACAGCA GCATCTGTTT CCTGATGCTG GTGAGCATCG ACCGCTACCT GGCCCTGGTG AAAACCATGT CCATGGGCCG GATGCGCGGC GTGCGCTGGG CCAAGCTCTA CAGCTTGGTG ATCTGGGGGT GTACGCTGCT CCTGAGCTCA CCCATGCTGG TGTTCCGGAC CATGAAGGAG TACAGCGATG AGGGCCACAA CGTCACCGCT TGTGTCATCA GCTACCCATC CCTCATCTGG GAAGTGTTCA CCAACATGCT CCTGAATGTC GTGGGCTTCC TGCTGCCCCT GAGTGTCATC ACCTTCTGCA CGATGCAGAT CATGCAGGTG CTGCGGAACA ACGAGATGCA GAAGTTCAAG GAGATCCAGA CGGAGAGGAG GGCCACGGTG CTAGTCCTGG TTGTGCTGCT GCTATTCATC ATCTGCTGGC TGCCCTTCCA GATCAGCACC TTCCTGGATA CGCTGCATCG CCTCGGCATC CTCTCCAGCT

GCCAGGACGA GCGCATCATC GATGTAATCA CACAGATCGC CTCCTTCATG GCCTACAGCA ACAGCTGCCT CAACCCACTG GTGTACGTGA TCGTGGGCAA GCGCTTCCGA AAGAAGTCTT GGGAGGTGTA CCAGGGAGTG TGCCAGAAAG GGGGCTGCAG GTCAGAACCC ATTCAGATGG AGAACTCCAT GGGCACACTG CGGACCTCCA TCTCCGTGGA ACGCCAGATT CACAAACTGC AGGACTGGGC AGGGAGCAGA CAGTGAGCAA ACGCCAGCAG GGCTGCTGTG AATTTGTGTA AGGATTGAGG GACAGTTGCT T ATGTTCTCTC CCTGGAAGAT ATCAATGTTT CTGTCTGTTC GTGAGGACTC CGTGCCCACC ACGGCCTCTT TCAGCGCCGA CATGCTCAAT GTCACCTTGC AAGGGCCCAC TCTTAACGGG ACCTTTGCCC AGAGCAAATG CCCCCAAGTG GAGTGGCTGG GCTGGCTCAA CACCATCCAG CCCCCCTTCC TCTGGGTGCT GTTCGTGCTG

GCCACCCTAG AGAACATCTT TGTCCTCAGC GTCTTCTGCC TGCACAAGAG CAGCTGCACG GTGGCAGAGA TCTACCTGGG GAACCTGGCC GCAGCAGACC TGATCCTGGC CTGCGGGCTG CCCTTCTGGG CCATCACCAT CTCCAACAAC TTCGACTGGC TCTTTGGGGA GACGCTCTGC CGCGTGGTGA ATGCCATTAT CTCCATGAAC CTGTACAGCA GCATCTGTTT CCTGATGCTG GTGAGCATCG ACCGCTACCT GGCCCTGGTG AAAACCATGT CCATGGGCCG GATGCGCGGC GTGCGCTGGG CCAAGCTCTA CAGCTTGGTG ATCTGGGGGT GTACGCTGCT CCTGAGCTCA CCCATGCTGG TGTTCCGGAC CATGAAGGAG TACAGCGATG AGGGCCACAA CGTCACCGCT TGTGTCATCA GCTACCCATC CCTCATCTGG GAAGTGTTCA CCAACATGCT CCTGAATGTC GTGGGCTTCC TGCTGCCCCT GAGTGTCATC ACCTTCTGCA CGATGCAGAT CATGCAGGTG CTGCGGAACA

ACGAGATGCA GAAGTTCAAG GAGATCCAGA CGGAGAGGAG GGCCACGGTG CTAGTCCTGG TTGTGCTGCT GCTATTCATC ATCTGCTGGC TGCCCTTCCA GATCAGCACC TTCCTGGATA CGCTGCATCG CCTCGGCATC CTCTCCAGCT GCCAGGACGA GCGCATCATC GATGTAATCA CACAGATCGC CTCCTTCATG GCCTACAGCA ACAGCTGCCT CAACCCACTG GTGTACGTGA TCGTGGGCAA GCGCTTCCGA AAGAAGTCTT GGGAGGTGTA CCAGGGAGTG TGCCAGAAAG GGGGCTGCAG GTCAGAACCC ATTCAGATGG AGAACTCCAT GGGCACACTG CGGACCTCCA TCTCCGTGGA ACGCCAGATT CACAAACTGC AGGACTGGGC AGGGAGCAGA CAGTGAGCAA ACGCCAGCAG GGCTGCTGTG AATTTGTGTA AGGATTGAGG GACAGTTGCT T GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG

GCTCCGAGGA GGGGTGGGGA CGGTGGGGAC ATCAGGCTGC CCCGCAGTAC CAGGGAGCGA CTGAAGTGCC CATGCCGCTT GCTCCGGAGA AGGTGGGTGC CGGGCAGGGG CTGCTCCAGC CGCCTCACCT CTGCTGGGAG GACAAACTGT CCCAGCACAG AGGGAGGGAG GGAGGGCAGG CAGCGGGGAG AAGTTTCCCT GTGGTCGTGG GGAGTT GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG GCTCCGAGGA GGGGTGGGGA CGGTGGTGAC GGTGGGGACA TCAGGCTGCC CCGCAGTACC AGGGAGCGAC TGAAGTGCCC ATGCCGCTTG CTCCGGAGAA GGTGGGTGCC GGGCAGGGGC TGCTCCAGCC GCCTCACCTC TGCTGGGAGG ACAAACTGTC CCAGCACAGA GGGAGGGAGG GAGGGCAGGC AGCGGGGAGA AGTTTCCCTG TGGTCGTGGG GAGTT GAGCTCTTCA ATATTTTAGT GAAAGCTATA

GATGAGGCTC CATAGGGGAT AAAGCACAGA CACACCTTTT CAGAGGGCTT GTGGACTCTG GGCAGCCTGT CCATAGACCT CTGTCCCCAA CTGGCAAGTC AGGAAACTCC AGATTAAGGA GCCCCAATGT GGTTGAACAG CCAGGTGCAC AGATGAGTCA ACCACACAGC CAGGCCAGGG AGGGCCTTCA CTCAAGAGCC TACAGCCAGT TCACAGCCAA GCCAGGGCTA GCGCCAGGCC ACCCATAAAC TGATCTGAGA CTCTGTTTCC CTGTCTCCAT GATGATGGGA TCAGGCTTGA TTGCTGGTTT GTAGGCTTGT TATGAATCAA GTCACAGGGA AGAGGAGCTG ATGGGCTGGG GGGACGTCCT CTGGCCCTCC TGTCTCTTCC CCAGATCCAC TGGGCCCACT CTTATCTGTT CTCTTCTGAA GGAAGGGTTT TAAGGCTTCA AAAAAAAATG TTTTGAAAGT CCCTGCCCTT TCCAGCTCCT ACCGTCTCAG CCCTGGGAGT GTAAAGTGCT GCAGATAGTT AGTAAGTCTT

TGAGCAAAAC TGAGAAAGCC AGCCTGAGCC TTGACATGGG AGAAACCTCC GCCATACATC TCCGAAGAAA CGGCCGCGTG TCTCAGGGGA GCGCAAACAC CCGTACCCAG GAAACAGGAC AGCTTCTGCC ACTGTCGCCC TTGGGAGCCG TACGTGGCAT GACAAAGAAA TCCCAGGACT CCGCCTGCCC ACCTGGCCAC CCTCTGTTTA CACCTTCCGC GTAAACGCCC ACTGTTTACA TCCAAAACTC AGACACAAAA TAACCACCTC AAGAAGATAA ATAATGATAA GAAATAAATG TTACGCGAGG CAAATTTATT CACATGGGGC TTCCCAGGCC ACTTTGTGGT CAGCCGGGAG GGACGTTTTT GCCGTCCCAC GACTCCAACG GGCAGCCGGG CCTACGCAAA GATGGAAATC TTCCAAGAGC CTCCCTGGCC CCCAGGGCTC AGAGGGTGGC AGAGCGGAGA GCGAAGGTGG CCGCAGCCTT CCCGGCCCCA CAGCCAGCCT GGCTCCAGCT GGGCAGGAGT

GCAGAGCTCA GCTGGAGGCG AGGGGGAAGT GCCCAGGAGG CTGATGACAT CACTACCCAG CCCTTCAAAG ATGAGCTGTT CCCGCCGCCA CTCCAGCTCT GGCTTCTGGG CTCCGAGGAG GGGTGGGGAC GGTGGTGACG GTGGGGACAT CAGGCTGCCC CGCAGTACCA GGGAGCGACT GAAGTGCCCA TGCCGCTTGC TCCGGAGAAG GTGGGTGCCG GGCAGGGGCT GCTCCAGCCG CCTCACCTCT GCTGGGAGGA CAAACTGTCC CAGCACAGAG GGAGGGAGGG AGGGCAGGCA GCGGGGAGAA GTTTCCCTGT GGTCGTGGGG AGTTGGGAAA AGTTCCCTTC CTTCCGGAGG GAGG CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG

TCTCCGGTAA AACACCGGAG ACTAATTCCT GCCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC AGGAGTGGAG GAGGCCTGGG GGGAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC TCCGTCCCTG CCCCAGCAAG ACAACTTAGA TCTCCAGGAG AACTGCCATC CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT CTTTAATCTA TTCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGAGGTC TGTGCCAAAG AAGAATCCAA TAAGCACATA TTGAGCACTT GCTGTATATG CAGTATTGAG CACTGTAGGC AAGACCCAAG AAAGAGAAGG AGCCATCTCC

ATCTTGAAGG AACTCAAAGA CTCAAGTGGG AACGACTGGG CACTGCCACC ACCAGAAAGC TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC ACAACCACCT GTCCCTGCCT CAGTTCCCTT TTATGTAACA TGAAGTCGTT GTGAGGGTTA AAGGCAGTAA CAGGTATAAA GTACTTAGAA AAGCAAAGGG TGCTACGTAC ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT ACTATAAGGA AAAGACACTG AGGTCTAGAA ATAGCTCCGT GGAGCAGAAT CAGTATTGGG AGCCGGTGGC GGTGTGAAGC ACCAGTGTCT GGCACACAGT AGGTGCTCAT TGGCTCCCTT CCACCTGTCA TTCCCACCAC CCTGAGGCCC CAACCGCCAC ACACACAGGA GCATTTGGAG AGAAGGCCAT GTCTTCAAAG TCTGATTTGT GATGAGGCAG AGGAAGATAT TTCTAATCGG

TCTTGCCCAG AGGATCACAG TGCTGAGACC CCCCACCACC AGCCGGTACC TGGGAAGGGG GAGAGTGCAG GCCTGCTCAG GGACTGTTCC TGTCTCAGCA ACCAAGGGAT TGTTCCTGTC AATCAATGGT TTATTGGAAG GTGGCCCAGT ATGAGCCCTA GAAGAGTGTG AAAAGGAATG GCAATGGTGT TCACCATCGG CAGTGCCAGG GCAGCACTCA TTCACTTGAT AAATGAATAT TTATTAGCTG GTTGGAGAGC TAGAACCTGG AGAGCTAGAA CCTGGAGAAC TAGAACCTGG AGGGCTAGAA CCTGGAGAGG CTAGAACCAA GAAGGGCTAG AACCTGGAGG GGCTAGAACC TAGAGAAGCT AAAACCTGAG CTAGAAGCTG GAGGACTAGA ACCTGGAGGG CTGGAATCTG AAGGGCTAGA ACCTGGAGGG CTGGAATCTG GAGAGCTAGA ACCTGGAGGG CTAGAACCTG GAGGGCTAGA ACCTAGAAGG GCTAGAACCT GGAGGGCTGG AATCTGGAGA

GCTAGAACCT GGAGGGCTAG AACCTGGAGG GCTAGAACCT AGAAGGGCTA GAACCTGGAG GGCTAGAACC TGGCAGGTTA GAACCTAGAA GGGCTAGAAC CTGGAGAGCC AGAACCTGGA GGGCTAGAAC CTGGAAGGGC TAGAACCTGT AGAGCTAGAA CATGGAGAGC TAGAACCCGG CAGGCTAGAA CCTGGCAAGC TAGAACCTGG AGGGAATGAA CCTGGAGGGC TAGAACCTGG AGAATGAGAA AAATTTACAT GGCAAAGAGC CCATAAATCC TGACCAATCC AACTCTGAAT TTTAAAGCAA AAGCGTGAAA AAAAAGATTC CCTCCTTACC CCCAACCCAC TCTTTTTTCC CACCACCCAC TCTCCTCTGC CTCAGTAAGT ATCTGGAGGA AGAAAACAGG TGAAAGAAGA AGTAAAAACC ATTTAGTATT AGTATTAGAA TGAAGTCAAA CTGTGCCACA CATGGTGAAT GAAAAAAAAA AAAAAGAGGC TGTGTTTTGT CACACAGGGC AGTCATTCAG

CACCAGAGCA CGTGATGGTC TGAGACTCTC TTAGGAGCAG AGCTCTGCCG CAATGGCCAT GTGGGGATCC ACACCTGGTC TGAGGGGCAA CTGAGTCTGC GGGAGAAGAG CGGCCCTATG CATGGTGTAG ATGCCCTGAT AAAGAACATC TGTCCTGTGA AAGACTCAAT GAGCTGTTAT GTTGTAAACA GGAAGCATTT CACATCCAAA CGAGAAAATC ATGTAAACAT GTGTCTTTTC TGTAGAGCAT AATAAATGGA TGAGGTTTTT GCAAAAAAAA AAAAAAAAA AAATGATAGA CCGTCAATAA TTTGTTAAAT GCTTTTTAAA ATGAATGCTT TAAGCCGGGT GCAGTGCCTC ACATCTGTAA TCCCAGCACT TTGGAGCCGA GCGGGTGGAT TGTGTGAGGT CAGGAGTTCG AGACCAACCT GGCCAACATG GCAAAACCTC ACTCTCTACC AAAAATACAA AAATTAGCCA GGCATGGTGG CAGGCACCTG TGATCCCAGC TACTCAGGAG GCTGAGACAG GAGAATCGCT

TGAACCCGGG AGGCAAGGTT GCAGTGAGCC AAGATTACGC CATTGTACTC CAGCCTGGGT GACAGAGAGA GACTCCGTCT CAAAAAAAAA AAAAAAAAAA AAAAAATTAC GCTTCAAACA CATGATCTCT CACCACTGTT GAATTTTCTT TCTATGAGCC CAGGAGGGCC TCTCAGAGAG GAAAGCTCCT AGGTCTTCCT TTCCCTCTGC AAACTCCCTG CCTTGAAGGT TCAGAAGGAC TGTGCGTGCT CGTTGCATCC TTTGCAAGTG TCCAAACCCT GATCCCAGCT GTGCTTAGGG GTTCCTGCAA ACCTTTTCCA GGTGTTAATT ACCTCCCACT TCATTTCCTG TTTACCAACT CAGCTTTTTG TTTTAGTGTG TTTGAATTCC CTGAACTGAC CGTTGTCTGA TCTCCACCTC CCAACTGAAT TAGGGGAGCT GGGCTTCTGG AAACCCAGGT GCCGGGTGTT GCAGAGTGGC TGAAAGCTGG GATGTGGCAG ATCCGTGGCT ACATTCATGC ACACACACAC ACCCACATAC

CCACACATGC ACACACACAC ACACACCCGC ACTCACACAC TTGGACATGC ATAGACCACA GCTTTCCACA CCCTTCCTAG ACAGGGGTCA CTTGGTATCC TGGAGAGAGT GTGAAGTCCT GGAATGGAAA GAGGGGGGAT TAAGCCCCAC CTCTAGCCAT GGGACTGAGA CAAGTCACCA CCAACCCATC TGCGCCTTGT TTACCTCCTC TGTGAGGCAA GCACAGAGCC CATGCCTGCC CCCCTGGATG GGAGTGATGT GAAACTTGAA GGGCGGTCAG AGCAAGGGTC GGGAATGGAA GGCCCTTGGG AAAAAAGGCC CTTTCAACTA GGGGCACAGA GGAGGCCCTG GGCTGAGAAC TTGACAGCAC CTTGTAATTG GTAAGCCAAG CCCGAAGGGA CTGGAAATAC TCAGATGTGT CTGTCTCCCT TATTAGGTTC AAAGTCCCTC AAGACCCTGT CTCCATCACA GTGCTCCAGT CCAGACCCCT CCTCTGAGCT CCAGACCCTG CTGGACCCAA CCAGCCCTAT GGGGTCGCAT

CCCCACCTGC CTGGAATTCT CCAAAGAACC TCCCCTTTAA CAGTTCCAGC CTTTAACAGT TCCAGTCTAA ACACATGACC TTTCTCCTCT AAATCAGCCC CCCATCTCTG CCTTTGCAGG AGATGGAAGC CATGACACCT GCCTCGCCCC TGTCCTCAGC CCATCCATGT CCAATCAAGC ACTAGGCATG TCAGGTTTAC CCTCTAAACT CCTCTGGAAT CCAGTCTCTC AGTCTCCATC ATCCCAGGTC GAAGCTAATG GGCTAACTGG TCCTTGCTTC CACTCTACCC CCACTGCAGT CCTGACTTCC TGAGCAGCAG CCAGGGCCTA ATCGATATTC ACACCAAGCG CCAACCTGAC TGAGATATCC TCCTGCACCA TCATCCCTCC ACCCTGTTTA GTTCTGCTCA CCCTCAGTGT TCTCATCAAT AATCCACTCC CCTCACAGGC GCGTTTGGGA CCCCATGTTC TATGCTCTCA CAGGACCTTT TGCTTGATTT TTCACTGTAC TTAGGTCAGT TTGCAGTTAT TAAGTGACTG AGCAATGTCT

GGCTTCTCCA GTAGACTGTC AGCTCCTAGC CATTGTATAC CTAGCACCGC TGTGTGGGAG CACGTGACAA ACGTCCAGTG AGTCAGGGAC TCAGCAGTCT CCATTTCTCC GCCCTGCTGG AGAATGCGTG TATTTGGCAA TCCCCAGCCC CTGTGCCATC TAACCATCTT TTCTTCTCTG TTCAGCCCAG GTGTGGCCTC ACTCACATCC CACTCTGAGT CCAAATGTTC TCTCCCTGGA AGATATCAAT GTTTCTGTCT GTTCGTGAGG ACTCCGTGCC CACCACGGCC TCTTTCAGGT GAGTCAAAGG GATTCCTCAG TTCACTAGTT AGGGGAGGTG GGCAGACACC CTGGAGAACT CCCTGGAAAG CTCAACTCTC ATGCCCCGGA CAACAGTTGA AGGAACCATG GTGATGTTAA GCCCAAAGAC AAAACCTCTC AGGTGTCCAA GTCCCTGTTG GAATCTTGGG AGCAGAGGGA ATGTTCTGTG GTCTAGAGGA AGAGGGGCTC AGGGAGGAGA AGGGCACATT CCTGGTTGTT ATATGTTTCT

ATCTATCCCA GATGAACTTG GAAGTGAAGG GAAGAGAGTT AAACATTAAA GTAAATACCC AGTGGATCAG ACAGCAATGT GCCAGATTGC CTTGGAAACA AAATATCTCC AACACATGGC TGACATTTGG TGGGAGATCA GAACACCCTA AAGAGAGAAT TTAAGGGGAG GGGGAGGAGG ACCTGAGCCA GAGTAGAAGC AGAGGATAGG GAGATCTGTT CTTGGGGACA GCATTTGCAA GAAACAAGGC TGAGGGGTCC ACTCCAACCT CTCCACCCTG CTGCAGGTGC TGCCTATGAT GAAGATGAGC AGATGGCCAT CTCAGCTGGG GCCACAGTGC ACTGGACCTA TAGTTTCCAA TTCCGCACTC AGCAGGCATC TTTCTGATGA TCCGATGGCT TCTCAGAGCC AGGGATGGGC CAGGATCCAT CCCCTTGGCT ACTGTCTTGC TGAGAAATTT ATAAGCAGCA TCTGGTGCTA TACTTTGGTC TCTAGTGAGT TAGCTCATGA AAGATGATAG ACTGTCCAAG CCAGGGGTAT

GCAGGAAATG GGTTTTCTGT AGCTACAGAA ATGGGGTTGA GGGTTGGACC AAGGGACTAC CCAGGGGAAG TCTTACCTTC AGAGGACTCT GGAAAGGAGG CTGCAAGTTT TCATGGGTCA AGAATTCAGA GCCCAGTAGA GACAGCTTAT CTCTGTTCCA AGATGTCTGG GGCCTTGGTT GGAAGATTCA AAGGCTAGGA AACCAGGAGC CACCAAAAGC GTAACTGGGG CCAGAGGATC CACTTTCAAG GTGGCAAGTT GGTTCCCCCC ATGTGGCTGC TTGAGTATCC TCACATGGCG GCTCACATCC TTCCAAGTAA GCAATGCAAA AGGCCAAGAA AGATGCTGCA AAGATGTTAT GACCTAGCCT CAGAAATCAC ACACCATCCC TGCCACCATT AGTAAGAAGT CCAGCCCACG TCCAGGAGAA GAGGAAGCAG ATTCCTCCTT TTGAAATGAA GAATATCAAG TAATTCGGGG GGCATATGAA AGCCACCACA CACCACAGGG ATCTTTTTAG AGCATACTTC TTATACCATC ACTGTAGTTC CTTAAGACTC AGGGGCAAAG CCTCACTTCC TTAGCACCCA GTGAAGACCA CGCTTACTCC CTCACTCAAC CTCTTGCTAC TTCCCACCTC TCCTGTCCAA CATCTAGTGT CACTTTCCAG AACATACCAA CAGCTTCCCC AGTTCTGTGC CTCTGCTCAG GCTGTTCCCC CTGCCTGGTC CACTTGTCCT CCTTCTTGTC CGGTCAAAAT GCTTCTTATC CTTCAAGACC CAGCTCTAGA GTCACCTCCA ACCCCTTACC CACCAGCCCC CTCTCCAAGT CTGTGTCCCA CAACCCCCCT GCTCCCTCCA GGGCACCCTC CACCCTCTGG GCCACAGTTG TCAGGAGTCA GGCAGGGCAG GGGCCGGGTG GTGTCTTCTT TGTGTTCTTG CACTCAGGGC AGAGCTCAGC ACAGAGCAGA CGCTCAAAAA ACATTTAAAG

GATAGAAGCA TTGATTTGTG GGTCCCCCAG TCTGGCTCCA GGATGCCAGC CAGCTGCTCC TAGAAGCAAA CGGACTTTTC CTGGGAAATC CCAGAGGTGA TGATCAGTAA TCTCTCCCGT GACTCGTAGT TCAGCTCTTC CTCCATGAGC CTGACTATCA GTGGACCTTC CAGAAAGAGC CCCTTTTCCT TCTCTCACCC ACAGCACAGG GCACTGGGAA AATGCCCAAT GAGTCCTGCC TCTGGGTTGT GCTTTGGACT TTTCAGTGTG TCTCGCATCC ACTCTTCAAC TTGAATGTTG CAACAGCCAT GAAAAAAGAA ATGCAAAGCG ATTCAGGATG AGAGCAATAC CCTACTCCAA AGAAGGCAAC ATAGAAGCTC AGAGAGATCA AGCAATTTGC CCAAGACCAC ACAGCTAGGA GTGGAACTCA TGGCTGTCCA AGCCCCATGC CTCTGCTGAA GGTAGAGATG AATTACAGCA ACAAGTCTAG AAAGGTGCCT GCCCTATGGT CTGTGAGTCT TGCCTAAGAA TGAAAGAGGA GCCAGTGGGT

TAAAGATGAG GTCACCAACA ACGGTGGTGT TGGAGTTTAC CACTGATAAT AAGGGTGCAA AATGTAAATT ACTAATGTTT ATTGAGCCTA GTGCAGTGCG TGGGGCATTT TGCACATTGT CTCTGATCCC TATGACAACC CTGAGAGGTA GTGGTTTTAA CTGCCATGTT ACAGGTGAGG TCATTGTGGT TCAAGGACGT TAAGTAACTT CCCCAGCGTG ACACGGCTTA TAAGTAAGGC AGCCAGGATG TGAACCCAGT AGGACTATCT GGCTGCAAAG TCCCCACCCC CCTCGCCATC TGTATCCTCC AATCACTTCA GTGCTTTGCT GCATAGAAGG TAACGGAAAT CACGATGCCA CAGACTGTCC AGGAAGACAG AAACTAGGCA GATGGGCTGG CCATGGTCTC CAAGCCAGAC TGGAATCTCC AGGTCTGGAA TGATATCATT TTTCTCTTTT AATAAATTAA CTCACCCACC ACACGGCTTT GAGAGGCTCA AAGTTGACCA ACTCCCTTGG GAGGGCCCCG GTTGATAAGG

AAGGAACGTG AATCCTCCCA TCACGGAAGC TTCAAGGAGG TCAAGGGTCC AACACTTGAG ATTGTTAGTG CTGTTGGTGG ATACTGGCCA AGGAAATATC CCAGTGGAGC CTCGAGATGA AGAACATGAG GCCCCCGTTT AGAACCAAGG ATCAGAGGGG GCTCTGTAAG ACCCAGGGGA GTCAGGTGCA CTGGAGCGCG GGCATGCAGA AAACAGCCTG AGCTCCACCT CGGCTTCTCC TTGTCCTGGC TGGTTGTCCT TAACCCCTGT CTCCTTCTGG ACCAGTTTTT GTCCTTCCCT TGTGACCGCT GAGGGGTAAC AGCCTCTTTC CACTTTCTTT CAGCGCCGAC ATGCTCAATG TCACCTTGCA AGGGCCCACT CTTAACGGGA CCTTTGCCCA GAGCAAATGC CCCCAAGTGG AGTGGCTGGG CTGGCTCAAC ACCATCCAGC CCCCCTTCCT CTGGGTGCTG TTCGTGCTGG CCACCCTAGA GAACATCTTT GTCCTCAGCG TCTTCTGCCT GCACAAGAGC AGCTGCACGG

TGGCAGAGAT CTACCTGGGG AACCTGGCCG CAGCAGACCT GATCCTGGCC TGCGGGCTGC CCTTCTGGGC CATCACCATC TCCAACAACT TCGACTGGCT CTTTGGGGAG ACGCTCTGCC GCGTGGTGAA TGCCATTATC TCCATGAACC TGTACAGCAG CATCTGTTTC CTGATGCTGG TGAGCATCGA CCGCTACCTG GCCCTGGTGA AAACCATGTC CATGGGCCGG ATGCGCGGCG TGCGCTGGGC CAAGCTCTAC AGCTTGGTGA TCTGGGGGTG TACGCTGCTC CTGAGCTCAC CCATGCTGGT GTTCCGGACC ATGAAGGAGT ACAGCGATGA GGGCCACAAC GTCACCGCTT GTGTCATCAG CTACCCATCC CTCATCTGGG AAGTGTTCAC CAACATGCTC CTGAATGTCG TGGGCTTCCT GCTGCCCCTG AGTGTCATCA CCTTCTGCAC GATGCAGATC ATGCAGGTGC TGCGGAACAA CGAGATGCAG AAGTTCAAGG AGATCCAGAC GGAGAGGAGG GCCACGGTGC

TAGTCCTGGT TGTGCTGCTG CTATTCATCA TCTGCTGGCT GCCCTTCCAG ATCAGCACCT TCCTGGATAC GCTGCATCGC CTCGGCATCC TCTCCAGCTG CCAGGACGAG CGCATCATCG ATGTAATCAC ACAGATCGCC TCCTTCATGG CCTACAGCAA CAGCTGCCTC AACCCACTGG TGTACGTGAT CGTGGGCAAG CGCTTCCGAA AGAAGTCTTG GGAGGTGTAC GAGGGAGTGT GCCAGAAAGG GGGCTGCAGG TCAGAACCCA TTCAGATGGA GAACTCCATG GGCACACTGC GGACCTCCAT CTCCGTGGAA CGCCAGATTC ACAAACTGCA GGACTGGGCA GGGAGCAGAC AGTGAGCAAA CGCCAGCAGG GCTGCTGTGA ATTTGTGTAA GGATTGAGGG ACAGTTGCTT TTCAGCATGG GCCCAGGAAT GCCAAGGAGA CATCTATGCA CGACCTTGGG AAATGAGTTG ATGTCTCCGG TAAAACACCG GAGACTAATT CCTGCCCTGC CCAATTTTGC

AGGGAGCATG GCTGTGAGGA TGGGGTGAAC TCACGCACAG CCAAGGACTC CAAAATCACA ACAGCATTAC TGTTCTTATT TGCTGCCACA CCTGAGCCAG CCTGCTCCTT CCCAGGAGTG GAGGAGGCCT GGGGGCAGGG AGAGGAGTGA CTGAGCTTCC CTCCCGTGTG TTCTCCGTCC CTGCCCCAGC AAGACAACTT AGATCTCCAG GAGAACTGCC ATCCAGCTTT GGTGCAATGG CTGAGTGCAC AAGTGAGTTG TTGCCCTGGG TTTCTTTAAT CTATTCAGCT AGAACTTTGA AGGACAATTT CTTGCATTAA TAAAGGTTAA GCCCTGAGGG GTCCCTGATA ACAACCTGGA GACCAGGATT TTATGGCTCC CCTCACTGAT GGACAAGGAG GTCTGTGCCA AAGAAGAATC CAATAAGCAC ATATTGAGCA CTTGCTGTAT ATGCAGTATT GAGCACTGTA GGCAAGAGGG AAGAAAGAGA AGGAGCCATC TCCATCTTGA AGGAACTCAA AGACTCAAGT GGGAACGACT

GGGCACTGCC ACCACCAGAA AGCTGTTCGA TGAGACGGTC GAGCAGGGTG CTGTGGGTGA TATGGACAGC AGAAGGGGGA GCCAGGTTCC AGCTCACCAA TACTATTGCA CACCACCTGT CCTGCCTC TGATCCTATC ACAACCTGAG AGTAGTTTTT ACTCCATTTA CAGGTGAGGT CATTGTGGTT CAAGGACGTT AAGTAACTTC CCCAGCTCAC ACGGCTTATA AGTAAGGCAG CCAGGATGTG AACCCAGTAG GACTATCTGG CTGCAAAGTC CCCACCCTCC CTCGCCATCT GTATCCTCCA ATCATCTTCA GTGCTTTGCT GATAGAAGGT ACGGAAATAC GATGCCACAG ACTGTCCAGG AAGACAGAAA CTAGGCAGAT GGGCTGGCCA TGGTCTCCAA GCCAGACTGG AATCTCCAGG TCTGGAATGA TATCATTTTT CTCTTTTAAT AAATTAACTC ACCCACCACA CGGCTTTGAG AGGCTCAAAG GTGACCAACT CCCTTGGGAG GGCCCCGGTT

GATAAGGAAG GAATGTGAAT CCTCCCATCA CGGAAGCTTC AAGGAGGTCA AGGGTCCAAC ACTTGAGATT GTTAGTGCTG TTGGTGGATA CTGCAGAATA TCCAGTGGAG CCTCAGATGA AGAACATGAG GCCCCGTTTA GATCCAAGGA TCAGAGGGGG CTCTGTAAGA CCCAGGGGAG TCAGGTGCAC TGGAGCGCGG GCTGCAGAAA ACAGCCTGAG CTCCACCTCG GCTTCTCCTT GCCCTGGCTG GTTGTCCTTA ACCCCTGTCT CCTTCTGGAC CAGTTTTTGT CCTTCCCTTG TGACCTGAGG GGTAACAGCC TCTTTTCCAC TTTCTTTCAG CGCCGACATG CTCAATGTCA CCTTGCAAGG GCCCACTCTT AACGGGACCT TTGCCCAGAG CAAATGCCCC CAAGTGGAGT GGCTGGGCTG GCTCAACACC ATCCAGCCCC CCTTCCTCTG GGTGCTGTTC GTGCTGGCCA CCCTAGAGAA CATCTTTGTC CTCAGCGTCT TCTGCCTGCA CAAGAGCAGC TGCACGGTGG

CAGAGATCTA CCTGGGGAAC CTGGCCGCAG CAGACCTGAT CCTGGCCTGC GGGCTGCCCT TCTGGGCCAT CACCATCTCC AACAACTTCG ACTGGCTCTT TGGGGAGACG CTCTGCCGCG TGGTGAATGC CATTATCTCC ATGAACCTGT ACAGCAGCAT CTGTTTCCTG ATGCTGGTGA GCATCGACCG CTACCTGGCC CTGGTGAAAA CCATGTCCAT GGGCCGGATG CGCGGCGTGC GCTGGGCCAA GCTCTACAGC TTGGTGATCT GGGGGTGTAC GCTGCTCCTG AGCTCACCCA TGCTGGTGTT CCGGACCATG AAGGAGTACA GCGATGAGGG CCACAACGTC ACCGCTTGTG TCATCAGCTA CCCATCCCTC ATCTGGGAAG TGTTCACCAA CATGCTCCTG AATGTCGTGG GCTTCCTGCT GCCCCTGAGT GTCATCACCT TCTGCACGAT GCAGATCATG CAGGTGCTGC GGAACAACGA GATGCAGAAG TTCAAGGAGA TCCAGACGGA GAGGAGGGCC ACGGTGCTAG TCCTGGTTGT

GCTGCTGCTA TTCATCATCT GCTGGCTGCC CTTCCAGATC AGCACCTTCC TGGATACGCT GCATCGCCTC GGCATCCTCT CCAGCTGCCA GGACGAGCGC ATCATCGATG TAATCACACA GATCGCCTCC TTCATGGCCT ACAGCAACAG CTGCCTCAAC CCACTGGTGT ACGTGATCGT GGGCAAGCGC TTCCGAAAGA AGTCTTGGGA GGTGTACCAG GGAGTGTGCC AGAAAGGGGG CTGCAGGTCA GAACCCATTC AGATGGAGAA CTCCATGGGC ACACTGCGGA CCTCCATCTC CGTGGAACGC CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTGTTGA TGTCTCCGGT AAAACACCGG AGACTAATTC CTGCCCTGCC CAATTTTCGA GGGAGCATGG

CTGTGAGGAT GGGGTGAACT CACGCACAGC CAAGGACTCC AAAATCACAA CAGCATTACT GTTCTTATTT GCTGCCACAC CTGAGCCAGC CTGCTCCTTC CCAGGAGTGG AGGAGGCCTG GGGGAGGGAG AGGAGTGACT GAGCTTCCCT CCCGTGTGTT CTCCGTCCCT GCCCCAGCAA GACAACTTAG ATCTCCAGGA GAACTGCCAT CCACGTTTGG TGCAATGGCT GAGTGCACAA GTGAGTTGTT GCCCTGGGTT TCTTTAATCT ATCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTTGATAAC AACCTGGAGA CCAGGATTTT ATGGCTCCCC TCACTGATGG ACAAGGAGGT CTGTGCCAAA GAAGAATCAA TAAGCACATA TGAGCACTTC TGTATATCAG TATTGAGCAC TGTAGGCA ATGTTCTCTC CCTGGAAGAT ATCAATGTTT CTGTCTGTTT GTGAGGACTC CGTGCCCACC ACGGCCTCTT TCAGCGCCGA CATGCTCAAT

GTCACCTTGC AAGGGCCCAC TCTTAACGGG ACCTTTGCCC AGAGCAAATG CCCCCAAGTG GAGTGGCTGG GCTGGCTCAA CACCATCCAG CCCCCCTTCC TCTGGGTGCT GTTCGTGCTG GCCACCCTAG AGAACATCTT TGTCCTCAGC GTCTTCTGCC TGCACAAGAG CAGCTGCACG GTGGCAGAGA TCTACCTGGG GAACCTGGCC GCAGCAGACC TGATCCTGGC CTGCGGGCTG CCCTTCTGGG CCATCACCAT CTCCAACAAC TTCGACTGGC TCTTTGGGGA GACGCTCTGC CGCGTGGTGA ATGCCATTAT CTCCATGAAC CTGTACAGCA GCATCTGTTT CCTGATGCTG GTGAGCATCG ACCGCTACCT GGCCCTGGTG AAAACCATGT CCATGGGCCG GATGCGCGGC GTGCGCTGGG CCAAGCTCTA CAGCTTGGTG ATCTGGGGGT GTACGCTGCT CCTGAGCTCA CCCATGCTGG TGTTCCGGAC CATGAAGGAG TACAGCGATG AGGGCCACAA CGTCACCGCT TGTGTCATCA

GCTACCCATC CCTCATCTGG GAAGTGTTCA CCAACATGCT CCTGAATGTC GTGGGCTTCC TGCTGCCCCT GAGTGTCATC ACCTTCTGCA CGATGCAGAT CATGCAGGTG CTGCGGAACA ACGAGATGCA GAAGTTCAAG GAGATCCAGA CGGAGAGGAG GGCCACGGTG CTAGTCCTGG TTGTGCTGCT GCTATTCATC ATCTGCTGGC TGCCCTTCCA GATCAGCACC TTCCTGGATA CGCTGCATCG CCTCGGCATC CTCTCCAGCT GCCAGGACGA GCGCATCATC GATGTAATCA CACAGATCGC CTCCTTCATG GCCTACAGCA ACAGCTGCCT CAACCCACTG GTGTACGTGA TCGTGGGCAA GCGCTTCCGA AAGAAGTCTT GGGAGGTGTA CCAGGGAGTG TGCCAGAAAG GGGGCTGCAG GTCAGAACCC ATTCAGATGG AGAACTCCAT GGGCACACTG CGGACCTCCA TCTCCGTGGA ACGCCAGATT CACAAACTGC AGGACTGGGC AGGGAGCAGA

CAGTGAGCAA ACGCCAGCAG GGCTGCTGTG AATTTGTGTA AGGATTGAGG GACAGTTGCT T ATGTTCTCTC CCTGGAAGAT ATCAATGTTT CTGTCTGTTC GTGAGGACTC CGTGCCCACC ACGGCCTCTT TCAGCGCCGA CATGCTCAAT GTCACCTTGC AAGGGCCCAC TCTTAACGGG ACCTTTGCCC AGAGCAAATG CCCCCAAGTG GAGTGGCTGG GCTGGCTCAA CACCATCCAG CCCCCCTTCC TCTGGGTGCT GTTCGTGCTG GCCACCCTAG AGAACATCTT TGTCCTCAGC GTCTTCTGCC TGCACAAGAG CAGCTGCACG GTGGCAGAGA TCTACCTGGG GAACCTGGCC GCAGCAGACC TGATCCTGGC CTGCGGGCTG CCCTTCTGGG CCATCACCAT CTCCAACAAC TTCGACTGGC TCTTTGGGGA GACGCTCTGC CGCGTGGTGA ATGCCATTAT CTCCATGAAC CTGTACAGCA GCATCTGTTT CCTGATGCTG GTGAGCATCG ACCGCTACCT GGCCCTGGTG AAAACCATGT

CCATGGGCCG GATGCGCGGC GTGCGCTGGG CCAAGCTCTA CAGCTTGGTG ATCTGGGGGT GTACGCTGCT CCTGAGCTCA CCCATGCTGG TGTTCCGGAC CATGAAGGAG TACAGCGATG AGGGCCACAA CGTCACCGCT TGTGTCATCA GCTACCCATC CCTCATCTGG GAAGTGTTCA CCAACATGCT CCTGAATGTC'GTGGGCTTCC TGCTGCCCCT GAGTGTCATC ACCTTCTGCA CGATGCAGAT CATGCAGGTG CTGCGGAACA ACGAGATGCA GAAGTTCAAG GAGATCCAGA CGGAGAGGAG GGCCACGGTG CTAGTCCTGG TTGTGCTGCT GCTATTCATC ATCTGCTGGC TGCCCTTCCA GATCAGCACC TTCCTGGATA CGCTGCATCG CCTCGGCATC CTCTCCAGCT GCCAGGACGA GCGCATCATC GATGTAATCA CACAGATCGC CTCCTTCATG GCCTACAGCA ACAGCTGCCT CAACCCACTG GTGTACGTGA TCGTGGGCAA GCGCTTCCGA AAGAAGTCTT

GGGAGGTGTA CCAGGGAGTG TGCCAGAAAG GGGGCTGCAG GTCAGAACCC ATTCAGATGG AGAACTCCAT GGGCACACTG CGGACCTCCA TCTCCGTGGA ACGCCAGATT CACAAACTGC AGGACTGGGC AGGGAGCAGA CAGTGAGCAA ACGCCAGCAG GGCTGCTGTG AATTTGTGTA AGGATTGAGG GACAGTTGCT T GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG GCTCCGAGGA GGGGTGGGGA CGGTGGGGAC ATCAGGCTGC CCCGCAGTAC CAGGGAGCGA CTGAAGTGCC CATGCCGCTT GCTCCGGAGA AGGTGGGTGC CGGGCAGGGG CTGCTCCAGC CGCCTCACCT CTGCTGGGAG GACAAACTGT CCCAGCACAG AGGGAGGGAG GGAGGGCAGG CAGCGGGGAG AAGTTTCCCT GTGGTCGTGG GGAGTT GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG

GCTCCGAGGA GGGGTGGGGA CGGTGGTGAC GGTGGGGACA TCAGGCTGCC CCGCAGTACC AGGGAGCGAC TGAAGTGCCC ATGCCGCTTG CTCCGGAGAA GGTGGGTGCC GGGCAGGGGC TGCTCCAGCC GCCTCACCTC TGCTGGGAGG ACAAACTGTC CCAGCACAGA GGGAGGGAGG GAGGGCAGGC AGCGGGGAGA AGTTTCCCTG TGGTCGTGGG GAGTT GAGCTCTTCA ATATTTTAGT GAAAGCTATA GATGAGGCTC CATAGGGGAT AAAGCACAGA CACACCTTTT CAGAGGGCTT GTGGACTCTG GGCAGCCTGT CCATAGACCT CTGTCCCCAA CTGGCAAGTC AGGAAACTCC AGATTAAGGA GCCCCAATGT GGTTGAACAG CCAGGTGCAC AGATGAGTCA ACCACACAGC CAGGCCAGGG AGGGCCTTCA CTCAAGAGCC TACAGCCAGT TCACAGCCAA GCCAGGGCTA GCGCCAGGCC ACCCATAAAC TGATCTGAGA CTCTGTTTCC

CTGTCTCCAT GATGATGGGA TCAGGCTTGA TTGCTGGTTT GTAGGCTTGT TATGAATCAA GTCACAGGGA AGAGGAGCTG ATGGGCTGGG GGGACGTCCT CTGGCCCTCC TGTCTCTTCC CCAGATCCAC TGGGCCCACT CTTATCTGTT CTCTTCTGAA GGAAGGGTTT TAAGGCTTCA AAAAAAAATG TTTTGAAAGT CCCTGCCCTT TCCAGCTCCT ACCGTCTCAG CCCTGGGAGT GTAAAGTGCT GCAGATAGTT AGTAAGTCTT TGAGCAAAAC TGAGAAAGCC AGCCTGAGCC TTGACATGGG AGAAACCTCC GCCATACATC TCCGAAGAAA CGGCCGCGTG TCTCAGGGGA GCGCAAACAC CCGTACCCAG GAAACAGGAC AGCTTCTGCC ACTGTCGCCC TTGGGAGCCG TACGTGGCAT GACAAAGAAA TCCCAGGACT CCGCCTGCCC ACCTGGCCAC CCTCTGTTTA CACCTTCCGC GTAAACGCCC ACTGTTTACA TCCAAAACTC AGACACAAAA TAACCACCTC

AAGAAGATAA ATAATGATAA GAAATAAATG TTACGCGAGG CAAATTTATT CACATGGGGC TTCCCAGGCC ACTTTGTGGT CAGCCGGGAG GGACGTTTTT GCCGTCCCAC GACTCCAACG GGCAGCCGGG CCTACGCAAA GATGGAAATC TTCCAAGAGC CTCCCTGGCC CCCAGGGCTC AGAGGGTGGC AGAGCGGAGA GCGAAGGTGG CCGCAGCCTT CCCGGCCCCA CAGCCAGCCT GGCTCCAGCT GGGCAGGAGT GCAGAGCTCA GCTGGAGGCG AGGGGGAAGT GCCCAGGAGG CTGATGACAT CACTACCCAG CCCTTCAAAG ATGAGCTGTT CCCGCCGCCA CTCCAGCTCT GGCTTCTGGG CTCCGAGGAG GGGTGGGGAC GGTGGTGACG GTGGGGACAT CAGGCTGCCC CGCAGTACCA GGGAGCGACT GAAGTGCCCA TGCCGCTTGC TCCGGAGAAG GTGGGTGCCG GGCAGGGGCT GCTCCAGCCG CCTCACCTCT GCTGGGAGGA CAAACTGTCC CAGCACAGAG GGAGGGAGGG AGGGCAGGCA GCGGGGAGAA GTTTCCCTGT GGTCGTGGGG AGTTGGGAAA AGTTCCCTTC CTTCCGGAGG GAGG -3' (FRAG NO 2275) (SEQ IDNO 12481)

5'- GAGCTCTTCA ATATTTTAGT GAAAGCTATA GATGAGGCTC CATAGGGGAT AAAGCACAGA CACACCTTTT CAGAGGGCTT GTGGACTCTG GGCAGCCTGT CCATAGACCT CTGTCCCCAA CTGGCAAGTC AGGAAACTCC AGATTAAGGA GCCCCAATGT GGTTGAACAG CCAGGTGCAC AGATGAGTCA ACCACACAGC CAGGCCAGGG

AGGGCCTTCA CTCAAGAGCC TACAGCCAGT TCACAGCCAA GCCAGGGCTA GCGCCAGGCC ACCCATAAAC TGATCTGAGA CTCTGTTTCC CTGTCTCCAT GATGATGGGA TCAGGCTTGA TTGCTGGTTT GTAGGCTTGT TATGAATCAA GTCACAGGGA AGAGGAGCTG ATGGGCTGGG GGGACGTCCT CTGGCCCTCC TGTCTCTTCC CCAGATCCAC TGGGCCCACT CTTATCTGTT CTCTTCTGAA GGAAGGGTTT TAAGGCTTCA AAAAAAAATG TTTTGAAAGT CCCTGCCCTT TCCAGCTCCT ACCGTCTCAG CCCTGGGAGT GTAAAGTGCT GCAGATAGTT AGTAAGTCTT TGAGCAAAAC TGAGAAAGCC AGCCTGAGCC TTGACATGGG AGAAACCTCC GCCATACATC TCCGAAGAAA CGGCCGCGTG TCTCAGGGGA GCGCAAACAC CCGTACCCAG GAAACAGGAC AGCTTCTGCC ACTGTCGCCC TTGGGAGCCG TACGTGGCAT GACAAAGAAA TCCCAGGACT CCGCCTGCCC

ACCTGGCCAC CCTCTGTTTA CACCTTCCGC GTAAACGCCC ACTGTTTACA TCCAAAACTC AGACACAAAA TAACCACCTC AAGAAGATAA ATAATGATAA GAAATAAATG TTACGCGAGG CAAATTTATT CACATGGGGC TTCCCAGGCC ACTTTGTGGT CAGCCGGGAG GGACGTTTTT GCCGTCCCAC GACTCCAACG GGCAGCCGGG CCTACGCAAA CATGGAAATC TTCCAAGAGC CTCCCTGGCC CCCAGGGCTC AGAGGGTGGC AGAGCGGAGA GCGAAGGTGG CCGCAGCCTT CCCGGCCCCA CAGCCAGCCT GGCTCCAGCT GGGCAGGAGT GCAGAGCTCA GCTGGAGGCG AGGGGGAAGT GCCCAGGAGG CTGATGACAT CACTACCCAG CCCTTCAAAG ATGAGGTGTT CCCGCCGCCA CTCCAGCTCT GGCTTCTGGG CTCCGAGGAG GGGTGGGGAC GGTGGTGACG GTGGGGACAT CAGGCTGCCC CGCAGTACCA GGGAGCGACT GAAGTGCCCA TGCCGCTTGC

TCCGGAGAAG GTGGGTGCCG GGCAGGGGCT GCTCCAGCCG CCTCACCTCT GCTGGGAGGA CAAACTGTCC CAGCACAGAG GGAGGGAGGG AGGGCAGGCA GCGGGGAGAA GTTTCCCTGT GGTCGTGGGG AGTTGGGAAA AGTTCCCTTC CTTCCGGAGG GAGG-3' (FRAGNO 2275) (SEQ ID NO 11830)

5'- GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG GCTCCGAGGA GGGGTGGGGA CGGTGGTGAC GGTGGGGACA TCAGGCTGCC CCGCAGTACC AGGGAGCGAC TGAAGTGCCC ATGCCGCTTG CTCCGGAGAA GGTGGGTGCC GGGCAGGGGC TGCTCCAGCC GCCTCACCTC TGCTGGGAGG ACAAACTGTC CCAGCACAGA GGGAGGGAGG GAGGGCAGGC AGCGGGGAGA AGTTTCCCTG TGGTCGTGGG GAGTT -3' (FRAG NO 2275) (SEQ ID NO 11829)

5'- GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG GCTCCGAGGA GGGGTGGGGA CGGTGGGGAC ATCAGGCTGC CCCGCAGTAC CAGGGAGCGA CTGAAGTGCC CATGCCGCTT GCTCCGGAGA AGGTGGGTGC CGGGCAGGGG CTGCTCCAGC CGCCTCACCT CTGCTGGGAG GACAAACTGT CCCAGCACAG AGGGAGGGAG GGAGGGCAGG CAGCGGGGAG AAGTTTCCCT GTGGTCGTGG GGAGTT-3' (FRAG NO 2275)(SEQ DD NO 11828) 5'- ATGTTCTCTC CCTGGAAGAT ATCAATGTTT CTGTCTGTTC GTGAGGACTC CGTGCCCACC ACGGCCTCTT TCAGCGCCGA CATGCTCAAT GTCACCTTGC AAGGGCCCAC TCTTAACGGG ACCTTTGCCC AGAGCAAATG CCCCCAAGTG GAGTGGCTGG GCTGGCTCAA CACCATCCAG CCCCCCTTCC TCTGGGTGCT GTTCGTGCTG GCCACCCTAG

AGAACATCTT TGTCCTCAGC GTCTTCTGCC TGCACAAGAG CAGCTGCACG GTGGCAGAGA TCTACCTGGG GAACCTGGCC GCAGCAGACC TGATCCTGGC CTGCGGGCTG CCCTTCTGGG CCATCACCAT CTCCAACAAC TTCGACTGGC TCTTTGGGGA GACGCTCTGC CGCGTGGTGA ATGCCATTAT CTCCATGAAC CTGTACAGCA GCATCTGTTT CCTGATGCTG GTGAGCATCG ACCGCTACCT GGCCCTGGTG AAAACCATGT CCATGGGCCG GATGCGCGGC GTGCGCTGGG CCAAGCTCTA CAGCTTGGTG ATCTGGGGGT GTACGCTGCT CCTGAGCTCA CCCATGCTGG TGTTCCGGAC CATGAAGGAG TACAGCGATG AGGGCCACAA CGTCACCGCT TGTGTCATCA GCTACCCATC CCTCATCTGG GAAGTGTTCA CCAACATGCT CCTGAATGTC GTGGGCTTCC TGCTGCCCCT GAGTGTCATC ACCTTCTGCA CGATGCAGAT CATGCAGGTG CTGCGGAACA ACGAGATGCA

GAAGTTCAAG GAGATCCAGA CGGAGAGGAG GGCCACGGTG CTAGTCCTGG TTGTGCTGCT GCTATTCATC ATCTGCTGGC TGCCCTTCCA GATCAGCACC TTCCTGGATA CGCTGCATCG CCTCGGCATC CTCTCCAGCT GCCAGGACGA GCGCATCATC GATGTAATCA CACAGATCGC CTCCTTCATG GCCTACAGCA ACAGCTGCCT CAACCCACTG GTGTACGTGA TCGTGGGCAA GCGCTTCCGA AAGAAGTCTT GGGAGGTGTA CCAGGGAGTG TGCCAGAAAG GGGGCTGCAG GTCAGAACCC ATTCAGATGG AGAACTCCAT GGGCACACTG CGGACCTCCA TCTCCGTGGA ACGCCAGATT CACAAACTGC AGGACTGGGC AGGGAGCAGA CAGTGAGCAA ACGCCAGCAG GGCTGCTGTG AATTTGTGTA AGGATTGAGG GACAGTTGCT T -3' (FRAG NO 2275) (SEQ ID NO 11827)

5'- ATGTTCTCTC CCTGGAAGAT ATCAATGTTT CTGTCTGTTT GTGAGGACTC CGTGCCCACC ACGGCCTCTT TCAGCGCCGA CATGCTCAAT GTCACCTTGC AAGGGCCCAC TCTTAACGGG ACCTTTGCCC AGAGCAAATG CCCCCAAGTG GAGTGGCTGG GCTGGCTCAA CACCATCCAG CCCCCCTTCC TCTGGGTGCT GTTCGTGCTG GCCACCCTAG AGAACATCTT TGTCCTCAGC GTCTTCTGCC TGCACAAGAG CAGCTGCACG GTGGCAGAGA TCTACCTGGG GAACCTGGCC GCAGCAGACC TGATCCTGGC CTGCGGGCTG CCCTTCTGGG CCATCACCAT CTCCAACAAC TTCGACTGGC TCTTTGGGGA GACGCTCTGC CGCGTGGTGA ATGCCATTAT CTCCATGAAC CTGTACAGCA GCATCTGTTT CCTGATGCTG GTGAGCATCG ACCGCTACCT GGCCCTGGTG AAAACCATGT CCATGGGCCG GATGCGCGGC GTGCGCTGGG CCAAGCTCTA CAGCTTGGTG ATCTGGGGGT

GTACGCTGCT CCTGAGCTCA CCCATGCTGG TGTTCCGGAC CATGAAGGAG TACAGCGATG AGGGCCACAA CGTCACCGCT TGTGTCATCA GCTACCCATC CCTCATCTGG GAAGTGTTCA CCAACATGCT CCTGAATGTC GTGGGCTTCC TGCTGCCCCT GAGTGTCATC ACCTTCTGCA CGATGCAGAT CATGCAGGTG CTGCGGAACA ACGAGATGCA GAAGTTCAAG GAGATCCAGA CGGAGAGGAG GGCCACGGTG CTAGTCCTGG TTGTGCTGCT GCTATTCATC ATCTGCTGGC TGCCCTTCCA GATCAGCACC TTCCTGGATA CGCTGCATCG CCTCGGCATC CTCTCCAGCT GCCAGGACGA GCGCATCATC GATGTAATCA CACAGATCGC CTCCTTCATG GCCTACAGCA ACAGCTGCCT CAACCCACTG GTGTACGTGA TCGTGGGCAA GCGCTTCCGA AAGAAGTCTT GGGAGGTGTA CCAGGGAGTG TGCCAGAAAG GGGGCTGCAG GTCAGAACCC ATTCAGATGG

AGAACTCCAT GGGCACACTG CGGACCTCCA TCTCCGTGGA ACGCCAGATT CACAAACTGC AGGACTGGGC AGGGAGCAGA CAGTGAGCAA ACGCCAGCAG GGCTGCTGTG AATTTGTGTA AGGATTGAGG GACAGTTGCT T -3' (FRAG NO 2275) (SEQ ID NO 11826)

5'- TGATCCTATC ACAACCTGAG AGTAGTTTTT ACTCCATTTA CAGGTGAGGT CATTGTGGTT CAAGGACGTT AAGTAACTTC CCCAGCTCAC ACGGCTTATA AGTAAGGCAG CCAGGATGTG AACCCAGTAG GACTATCTGG CTGCAAAGTC CCCACCCTCC CTCGCCATCT GTATCCTCCA ATCATCTTCA GTGCTTTGCT GATAGAAGGT ACGGAAATAC GATGCCACAG ACTGTCCAGG AAGACAGAAA CTAGGCAGAT GGGCTGGCCA TOGTCTCCAA GCCAGACTGG AATCTCCAGG TCTGGAATGA TATCATTTTT

CTCTTTTAAT AAATTAACTC ACCCACCACA CGGCTTTGAG AGGCTCAAAG GTGACCAACT CCCTTGGGAG GGCCCCGGTT GATAAGGAAG GAATGTGAAT CCTCCCATCA CGGAAGCTTC AAGGAGGTCA AGGGTCCAAC ACTTGAGATT GTTAGTGCTG TTGGTGGATA CTGCAGAATA TCCAGTGGAG CCTCAGATGA AGAACATGAG GCCCCGTTTA GATCCAAGGA TCAGAGGGGG CTCTGTAAGA CCCAGGGGAG TCAGGTGCAC TGGAGCGCGG GCTGCAGAAA ACAGCCTGAG CTCCACCTCG GCTTCTCCTT GCCCTGGCTG GTTGTCCTTA ACCCCTGTCT CCTTCTGGAC CAGTTTTTGT CCTTCCCTTG TGACCTGAGG GGTAACAGCC TCTTTTCCAC TTTCTTTCAG CGCCGACATG CTCAATGTCA CCTTGCAAGG GCCCACTCTT AACGGGACCT TTGCCCAGAG CAAATGCCCC CAAGTGGAGT GGCTGGGCTG GCTCAACACC ATCCAGCCCC CCTTCCTCTG GGTGCTGTTC

GTGCTGGCCA CCCTAGAGAA CATCTTTGTC CTCAGCGTCT TCTGCCTGCA CAAGAGCAGC TGCACGGTGG CAGAGATCTA CCTGGGGAAC CTGGCCGCAG CAGACCTGAT CCTGGCCTGC GGGCTGCCCT TCTGGGCCAT CACCATCTCC AACAACTTCG ACTGGCTCTT TGGGGAGACG CTCTGCCGCG TGGTGAATGC CATTATCTCC ATGAACCTGT ACAGCAGCAT CTGTTTCCTG ATGCTGGTGA GCATCGACCG CTACCTGGCC CTGGTGAAAA CCATGTCCAT GGGCCGGATG CGCGGCGTGC GCTGGGCCAA GCTCTACAGC TTGGTGATCT GGGGGTGTAC GCTGCTCCTG AGCTCACCCA TGCTGGTGTT CCGGACCATG AAGGAGTACA GCGATGAGGG CCACAACGTC ACCGCTTGTG TCATCAGCTA CCCATCCCTC ATCTGGGAAG TGTTCACCAA CATGCTCCTG AATGTCGTGG GCTTCCTGCT GCCCCTGAGT GTCATCACCT TCTGCACGAT GCAGATCATG CAGGTGCTGC

GGAACAACGA GATGCAGAAG TTCAAGGAGA TCCAGACGGA GAGGAGGGCC ACGGTGCTAG TCCTGGTTGT GCTGCTGCTA TTCATCATCT GCTGGCTGCC CTTCCAGATC AGCACCTTCC TGGATACGCT GCATCGCCTC GGCATCCTCT CCAGCTGCCA GGACGAGCGC ATCATCGATG TAATCACACA GATCGCCTCC TTCATGGCCT ACAGCAACAG CTGCCTCAAC CCACTGGTGT ACGTGATCGT GGGCAAGCGC TTCCGAAAGA AGTCTTGGGA GGTGTACCAG GGAGTGTGCC AGAAAGGGGG CTGCAGGTCA GAACCCATTC AGATGGAGAA CTCCATGGGC ACACTGCGGA CCTCCATCTC CGTGGAACGC CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTGTTGA

TGTCTCCGGT AAAACACCGG AGACTAATTC CTGCCCTGCC CAATTTTCGA GGGAGCATGG CTGTGAGGAT GGGGTGAACT CACGCACAGC CAAGGACTCC AAAATCACAA CAGCATTACT GTTCTTATTT GCTGCCACAC CTGAGCCAGC CTGCTCCTTC CCAGGAGTGG AGGAGGCCTG GGGGAGGGAG AGGAGTGACT GAGCTTCCCT CCCGTGTGTT CTCCGTCCCT GCCCCAGCAA GACAACTTAG ATCTCCAGGA GAACTGCCAT CCACGTTTGG TGCAATGGCT GAGTGCACAA GTGAGTTGTT GCCCTGGGTT TCTTTAATCT ATCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTTGATAAC AACCTGGAGA CCAGGATTTT ATGGCTCCCC TCACTGATGG ACAAGGAGGT CTGTGCCAAA GAAGAATCAA TAAGCACATA TGAGCACTTC TGTATATCAG TATTGAGCAC TGTAGGCA -3' (FRAG NO 2275) (SEQ DD NO 11825)

5'- CTGCAGAAAA CAGCCTGAGC TCCACCTCGG CTTCTCCTTG CCCTGGCTGG TTGTCCTTAA CCCCTGTCTC CTTCTGGACC AGTTTTTGTC CTTCCCTTGT GACCCTGAGG GGTAACAGCC TCTTTTCCAC TTTCTTTCAG CGCCGACATG CTCAATGTCA CCTTGCAAGG GCCCACTCTT AACGGGACCT TTGCCCAGAG CAAATGCCCC CAAGTGGAGT GGCTGGGCTG GCTCAACACC ATCCAGCCCC CCTTCCTCTG GGTGCTGTTC GTGCTGGCCA CCCTAGAGAA CATCTTTGTC CTCAGCGTCT TCTGCCTGCA CAAGAGCAGC TGCACGGTGG CAGAGATCTA CCTGGGGAAC CTGGCCGCAG CAGACCTGAT CCTGGCCTGC GGGCTGCCCT TCTGGGCCAT CACCATCTCC AACAACTTCG ACTGGCTCTT TGGGGAGACG CTCTGCCGCG TGGTGAATGC CATTATCTCC ATGAACCTGT ACAGCAGCAT CTGTTTCCTG ATGCTGGTGA GCATCGACCG CTACCTGGCC CTGGTGAAAA

CCATGTCCAT GGGCCGGATG CGCGGCGTGC GCTGGGCCAA GCTCTACAGC TTGGTGATCT GGGGGTGTAC GCTGCTCCTG AGCTCACCCA TGCTGGTGTT CCGGACCATG AAGGAGTACA GCGATGAGGG CCACAACGTC ACCGCTTGTG TCATCAGCTA CCCATCCCTC ATCTGGGAAG TGTTCACCAA CATGCTCCTG AATGTCGTGG GCTTCCTGCT GCCCCTGAGT GTCATCACCT TCTGCACGAT GCAGATCATG CAGGTGCTGC GGAACAACGA GATGCAGAAG TTCAAGGAGA TCCAGACGGA GAGGAGGGCC ACGGTGCTAG TCCTGGTTGT GCTGCTGCTA TTCATCATCT GCTGGCTGCC CTTCCAGATC AGCACCTTCC TGGATACGCT GCATCGCCTC GGCATCCTCT CCAGCTGCCA GGACGAGCGC ATCATCGATG TAATCACACA GATCGCCTCC TTCATGGCCT ACAGCAACAG CTGCCTCAAC CCACTGGTGT ACGTGATCGT GGGCAAGCGC TTCCGAAAGA

AGTCTTGGGA GGTGTACCAG GGAGTGTGCC AGAAAGGGGG CTGCAGGTCA GAACCCATTC AGATGGAGAA CTCCATGGGC ACACTGCGGA CCTCCATCTC CGTGGAACGC CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG TCTCCGGTAA AACACCGGAG ACTAATTCCT GNCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC AGGAGTGGAG GAGGCCTGGG GGCAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC TCCGTCCCTG CCCCAGCAAG ACAACTTAGA TCTCCAGGAG

AACTGCCATC CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT CTTTAATCTA TTCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGGAGGT CTGTGCCAAA GAAGAATCCA ATAAGCACAT ATTGAGCACT TGCTGTATAT GCAGTATTGA GCACTGTAGG CAAGAGGGAA GAAAGAGAAG GAGCCATCTC CATCTTGAAG GAACTCAAAG ACTCAAGTGG GAACGACTGG CACTGCCACC ACCAGAAAGC TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC ACAACCACCT GTCCCTGCCT CAGTTCCCTC TTCTGTAACA TGAAGTCGTT GTGAGGGTTA AAGGCAGTAA CAGGTATAAA GTACTTAGAA

AAGCAAAGGG TGCTACGTAC ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT ACTATAAGGA AAAGACACTG AGGTCTAGA -3' (FRAG NO 2275) (SEQ DD NO 11824)

5'- AAATGATAGA CCGTCAATAA TTTGTTAAAT GCTTTTTAAA ATGAATGCTT TAAGCCGGGT GCAGTGCCTC ACATCTGTAA TCCCAGCACT TTGGAGCCGA GCGGGTGGAT TGTGTGAGGT CAGGAGTTCG AGACCAACCT GGCCAACATG GCAAAACCTC ACTCTCTACC AAAAATACAA AAATTAGCCA GGCATGGTGG CAGGCACCTG TGATCCCAGC TACTCAGGAG GCTGAGACAG GAGAATCGCT TGAACCCGGG AGGCAAGGTT GCAGTGAGCC AAGATTACGC CATTGTACTC CAGCCTGGGT

GACAGAGAGA GACTCCGTCT CAAAAAAAAA AAAAAAAAAA AAAAAATTAC GCTTCAAACA CATGATCTCT CACCACTGTT GAATTTTCTT TCTATGAGCC GAGGAGGGCC TCTCAGAGAG GAAAGCTCCT AGGTCTTCCT TTCCCTCTGC AAACTCCCTG CCTTGAAGGT TCAGAAGGAC TGTGCGTGCT CGTTGCATCC TTTGCAAGTG TCCAAACCCT GATCCCAGCT GTGCTTAGGG GTTCCTGCAA ACCTTTTCCA GGTGTTAATT ACCTCCCACT TCATTTCCTG TTTACCAACT CAGCTTTTTG TTTTAGTGTG TTTGAATTCC CTGAACTGAC CGTTGTCTGA TCTCCACCTC CCAACTGAAT TAGGGGAGCT GGGCTTCTGG AAACCCAGGT GCCGOGTGTT GCAGAGTGGC TGAAAGCTGO GATGTGGCAG ATCCGTGGCT ACATTCATGC ACACACACAC ACCCACATAC CCACACATGC ACACACACAC ACACACCCGC ACTCACACAC TTGGACATGC ATAGACCACA GCTTTCCACA CCCTTCCTAG ACAGGGGTCA CTTGGTATCC TGGAGAGAGT GTGAAGTCCT GGAATGGAAA GAGGGGGGAT TAAGCCCCAC CTCTAGCCAT GGGACTGAGA CAAGTCACCA CCAACCCATC TGCGCCTTGT TTACCTCCTC TGTGAGGCAA GCACAGAGCC CATGCCTGCC CCCCTGGATG GGAGTGATGT GAAACTTGAA GGGCGGTCAG AGCAAGGGTC GGGAATGGAA GGCCCTTGGG AAAAAAGGCC CTTTCAACTA GGGGCACAGA GGAGGCCCTG GGCTGAGAAC TTGACAGCAC CTTGTAATTG GTAAGCCAAG CCCGAAGGGA CTGGAAATAC TCAGATGTGT CTGTCTCCCT TATTAGGTTC AAAGTCCCTC AAGACCCTGT CTCCATCACA GTGCTCCAGT CCAGACCCCT CCTCTGAGCT

CCAGACCCTG CTGGACCCAA CCAGCCCTAT GGGGTCGCAT CCCCACCTGC CTGGAATTCT CCAAAGAACC TCCCCTTTAA CAGTTCCAGC CTTTAACAGT TCCAGTCTAA ACACATGACC TTTCTCCTCT AAATCAGCCC CCCATCTCTG CCTTTGCAGG AGATGGAAGC CATGACACCT GCCTCGCCCC TGTCCTCACC CCATCCATGT CCAATCAAGC ACTAGGCATG TCAGGTTTAC CCTCTAAACT CCTCTGGAAT CCAGTCTCTC AGTCTCCATC ATCCCAGGTC GAAGCTAATG GGCTAACTGG TCCTTGCTTC CACTCTACCC CCACTGCAGT CCTGACTTCC TGAGCAGCAG CCAGGGCCTA ATCGATATTC ACACCAAGCG CCAACCTGAC TGAGATATCC TCCTGCACCA TCATCCCTCC ACCCTGTTTA GTTCTGCTCA CCCTCAGTGT TCTCATCAAT AATCCACTCC CCTCACAGGC GCGTTTGGGA CCCCATGTTC TATGCTCTCA CAGGACCTTT TGCTTGATTT TTCACTGTAC

TTAGGTCAGT TTGCAGTTAT TAAGTGACTG AGCAATGTCT GGCTTCTCCA GTAGACTGTC AGCTCCTAGC CATTGTATAC CTAGCACCGC TGTGTGGGAG CACGTGACAA ACGTCCAGTG AGTCAGGGAC TCAGCAGTCT CCATTTCTCC GCCCTGCTGG AGAATGCGTG TATTTGGCAA TCCCCAGCCC CTGTGCCATC TAACCATCTT TTCTTCTCTG TTCAGCCCAG GTGTGGCCTC ACTCACATCC CACTCTGAGT CCAAATGTTC TCTCCCTGGA AGATATCAAT GTTTCTGTCT GTTCGTGAGG ACTCCGTGCC CACCACGGCC TCTTTCAGGT GAGTCAAAGG GATTCCTCAG TTCACTAGTT AGGGGAGGTG GGCAGACACC CTGGAGAACT CCCTGGAAAG CTCAACTCTC ATGCCCCGGA CAACAGTTGA AGGAACCATG GTGATGTTAA GCCCAAAGAC AAAACCTCTC AGGTGTCCAA GTCCCTGTTG GAATCTTGGG AGCAGAGGGA ATGTTCTGTG GTCTAGAGGA AGAGGGGCTC

AGGGAGGAGA AGGGCACATT CCTGGTTGTT ATATGTTTCT ATCTATCCCA GATGAACTTG GAAGTGAAGG GAAGAGAGTT AAACATTAAA GTAAATACCC AGTGGATCAG ACAGCAATGT GCCAGATTGC CTTGGAAACA AAATATCTCC AACACATGGC TGACATTTGG TGGGAGATCA GAACACCCTA AAGAGAGAAT TTAAGGGGAG GGGGAGGAGG ACCTGAGCCA GAGTAGAAGC AGAGGATAGG GAGATCTGTT CTTGGGGACA GCATTTGCAA GAAACAAGGC TGAGGGGTCC ACTCCAACCT CTCCACCCTG CTGCAGGTGC TGCCTATGAT GAAGATGAGC AGATGGCCAT CTCAGCTGGG GCCACAGTGC ACTGGACCTA TAGTTTCCAA TTCCGCACTC AGCAGGCATC TTTCTGATGA TCCGATGGCT TCTCAGAGCC AGGGATGGGC CAGGATCCAT CCCCTTGGCT ACTGTCTTGC TGAGAAATTT ATAAGCAGCA TCTGGTGCTA TACTTTGGTC

TCTAGTGAGT TAGCTCATGA AAGATGATAG ACTCTCCAAG CCAGGGGTAT GCAGGAAATG GGTTTTCTGT AGCTACAGAA ATGGGGTTGA GGGTTGGACC AAGGGACTAC CCAGGGGAAG TCTTACCTTC AGAGGACTCT GGAAAGGAGG CTGCAAGTTT TCATGGGTCA AGAATTCAGA GCCCAGTAGA GACAGCTTAT CTCTGTTCCA AGATGTCTGG GGCCTTGGTT GGAAGATTCA AAGGCTAGGA AACCAGGAGC CACCAAAAGC GTAACTGGGG CCAGAGGATC CACTTTCAAG GTGGCAAGTT GGTTCCCCCC ATGTGGCTGC TTGAGTATCC TCACATGGCG GCTCACATCC TTCCAAGTAA GCAATGCAAA AGGCCAAGAA AGATGCTGCA AAGATGTTAT GACCTAGCCT CAGAAATCAC ACACCATCCC TGCCACCATT AGTAAGAAGT CCAGCCCACG TCCAGGAGAA GAGGAAGCAG ATTCCTCCTT TTGAAATGAA GAATATCAAG TAATTCGGGG GGCATATGAA AGCCACCACA

CACCACAGGG ATCTTTTTAG AGCATACTTC TTATACCATC ACTGTAGTTC CTTAAGACTC AGGGGCAAAG CCTGACTTCC TTAGCACCCA GTGAAGACCA CGCTTACTCC CTCACTCAAC CTCTTGCTAC TTCCCACCTC TCCTGTCCAA CATCTAGTGT CACTTTCCAG AACATACCAA CAGCTTCCCC AGTTCTGTGC CTCTGCTCAG GCTGTTCCCC CTGCCTGGTC CACTTGTCCT CCTTCTTGTC CGGTCAAAAT GCTTCTTATC CTTCAAGACC CAGCTCTAGA GTCACCTCCA ACCCCTTACC CACCAGCCCC CTCTCCAAGT CTGTGTCCCA CAACCCCCCT GCTCCCTCCA GGGCACCCTC CACCCTCTGG GCCACAGTTG TCAGGAGTCA GGCAGGGCAG GGGCCGGGTG GTGTCTTCTT TGTGTTCTTG CACTCAGGGC AGAGCTCAGC ACAGAGCAGA CGCTCAAAAA ACATTTAAAG GATAGAAGCA TTGATTTGTG GGTCCCCCAG TCTGGCTCCA GGATGCCAGC CAGCTGCTCC

TAGAAGCAAA CGGACTTTTC CTGGGAAATC CCAGAGGTGA TGATCAGTAA TCTCTCCCGT GACTCGTAGT TCAGCTCTTC CTCCATGAGC CTGACTATCA GTGGACCTTC CAGAAAGAGC CCCTTTTCCT TCTCTCACCC ACAGCACAGG GCACTGGGAA AATGCCCAAT GAGTCCTGCC TCTGGGTTGT GCTTTGGACT TTTCAGTGTG TCTCGCATCC ACTCTTCAAC TTGAATGTTG CAACAGCCAT GAAAAAAGAA ATGCAAAGCG ATTCAGGATG AGAGCAATAC CCTACTCCAA AGAAGGCAAC ATAGAAGCTC AGAGAGATCA AGCAATTTGC CCAAGACCAC ACAGCTAGGA GTGGAACTCA TGGCTGTCCA AGCCCCATGC CTCTGCTGAA GGTAGAGATG AATTACAGCA ACAAGTCTAG AAAGGTGCCT GCCCTATGGT CTGTGAGTCT TGCCTAAGAA TGAAAGAGGA GCCAGTGGGT TAAAGATGAG GTCACCAACA ACGGTGGTGT TGGAGTTTAC CACTGATAAT AAGGGTGCAA

AATGTAAATT ACTAATGTTT ATTGAGCCTA GTGCAGTGCG TGGGGCATTT TGCACATTGT CTCTGATCCC TATGACAACC CTGAGAGGTA GTGGTTTTAA CTGCCATGTT ACAGGTGAGG TCATTGTGGT TCAAGGACGT TAAGTAACTT CCCCAGCGTG ACACGGCTTA TAAGTAAGGC AGCCAGGATG TGAACCCAGT AGGACTATCT GGCTGCAAAG TCCCCACCCC CCTCGCCATC TGTATCCTCC AATCACTTCA GTGCTTTGCT GCATAGAAGG TAACGGAAAT CACGATGCCA CAGACTGTCC AGGAAGACAG AAACTAGGCA GATGGGCTGG CCATGGTCTC CAAGCCAGAC TGGAATCTCC AGGTCTGGAA TGATATCATT TTTGTCTTTT AATAAATTAA CTCACCCACC ACACGGCTTT GAGAGGCTCA AAGTTGACCA ACTCCCTTGG GAGGGCCCCG GTTGATAAGG AAGGAACGTG AATCCTCCCA TCACGGAAGC TTCAAGGAGG TCAAGGGTCC AACACTTGAG ATTGTTAGTG AGAACATGAG AGAACCAAGG ATCAGAGGGG GCTCTGTAAG ACCCAGGGGA GTCAGGTGCA CTGGAGCGCG GGCATGCAGA AAACAGCCTG AGCTCCACCT CGGCTTCTCC TTGTCCTGGC TGGTTGTCCT TAACCCCTGT CTCCTTCTGG ACCAGTTTTT GTCCTTCCCT TGTGACCGCT GAGGGGTAAC AGCCTCTTTC CACTTTGTTT CAGCGCCGAC ATGCTCAATG TCACCTTGCA AGGGCCCACT CTTAACGGGA CCTTTGCCCA GAGCAAATGC CCCCAAGTGG AGTGGCTGGG CTGGCTCAAC ACCATCCAGC CCCCCTTCCT CTGGGTGCTG TTCGTGCTGG CCACCCTAGA GAACATCTTT GTCCTCAGCG TCTTCTGCCT GCACAAGAGC AGCTGCACGG TGGCAGAGAT CTACCTGGGG AACCTGGCCG CAGCAGACCT GATCCTGGCC TGCGGGCTGC CCTTCTGGGC

CATCACCATC TCCAACAACT TCGACTGGCT CTTTGGGGAG ACGCTCTGCC GCGTGGTGAA TGCCATTATC TCCATGAACC TGTACAGCAG CATCTGTTTC CTGATGCTGG TGAGCATCGA CCGCTACCTG GCCCTGGTGA AAACCATGTC CATGGGCCGG ATGCGCGGCG TGCGCTGGGC CAAGCTCTAC AGCTTGGTGA TCTGGGGGTG TACGCTGCTC CTGAGCTCAC CCATGCTGGT GTTCCGGACC ATGAAGGAGT ACAGCGATGA GGGCCACAAC GTCACCGCTT GTGTCATCAG CTACCCATCC CTCATCTGGG AAGTGTTCAC CAACATGCTC CTGAATGTCG TGGGCTTCCT GCTGCCCCTG AGTGTCATCA CCTTCTGCAC GATGCAGATC ATGCAGGTGC TGCGGAACAA CGAGATGCAG AAGTTCAAGG AGATCCAGAC GGAGAGGAGG GCCACGGTGC TAGTCCTGGT TGTGCTGCTG CTATTCATCA TCTGCTGGCT GCCCTTCCAG ATCAGCACCT TCCTGGATAC GCTGCATCGC

CTCGGCATCC TCTCCAGCTG CCAGGACGAG CGCATCATCG ATGTAATCAC ACAGATCGCC TCCTTCATGG CCTACAGCAA CAGCTGCCTC AACCCACTGG TGTACGTGAT CGTGGGCAAG CGCTTCCGAA AGAAGTCTTG GGAGGTGTAC CAGGGAGTGT GCCAGAAAGG GGGCTGCAGG TCAGAACCCA TTCAGATGGA GAACTCCATG GGCACACTGC GGACCTCCAT CTCCGTGGAA CGCCAGATTC ACAAACTGCA GGACTGGGCA GGGAGCAGAC AGTGAGCAAA CGCCAGCAGG GCTGCTGTGA ATTTGTGTAA GGATTGAGGG ACAGTTGCTT TTCAGCATGG GCCCAGGAAT GCCAAGGAGA CATCTATGCA CGACCTTGGG AAATGAGTTG ATGTCTCCGG TAAAACACCG GAGACTAATT CCTGCCCTGC CCAATTTTGC AGGGAGCATG GCTGTGAGGA TGGGGTGAAC TCACGCACAG CCAAGGACTC CAAAATCACA ACAGCATTAC TGTTCTTATT

TGCTGCCACA CCTGAGCCAG CCTGCTCCTT CCCAGGAGTG GAGGAGGCCT GGGGGCAGGG AGAGGAGTGA CTGAGCTTCC CTCCCGTGTG TTCTCCGTCC CTGCCCCAGC AAGACAACTT AGATCTCCAG GAGAACTGCC ATCCAGCTTT GGTGCAATGG CTGAGTGCAC AAGTGAGTTG TTGCCCTGGG TTTCTTTAAT CTATTCAGCT AGAACTTTGA AGGACAATTT CTTGCATTAA TAAAGGTTAA GCCCTGAGGG GTCCCTGATA ACAACCTGGA GACCAGGATT TTATGGCTCC CCTCACTGAT GGACAAGGAG GTCTGTGCCA AAGAAGAATC CAATAAGCAC ATATTGAGCA CTTGCTGTAT ATGCAGTATT GAGCACTGTA GGCAAGAGGG AAGAAAGAGA AGGAGCCATC TCCATCTTGA AGGAACTCAA AGACTCAAGT GGGAACGACT GGGCACTGCC ACCACCAGAA AGCTGTTCGA TGAGACGGTC GAGCAGGGTG CTGTGGGTGA TATGGACAGC AGAAGGGGGA

GCCAGGTTCC AGCTCACCAA TACTATTGCA CACCACCTGT CCTGCCTC -3' (FRAG NO 2275) (SEQ ID NO 11823)

5'- CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG TCTCCGGTAA AACACCGGAG ACTAATTCCT GCCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC AGGAGTGGAG GAGGCCTGGG GGGAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC TCCGTCCCTG CCCCAGCAAG ACAACTTAGA TCTCCAGGAG AACTGCCATC

CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT CTTTAATCTA TTCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGAGGTC TGTGCCAAAG AAGAATCCAA TAAGCACATA TTGAGCACTT GCTGTATATG CAGTATTGAG CACTGTAGGC AAGACCCAAG AAAGAGAAGG AGCCATCTCC ATCTTGAAGG AACTCAAAGA CTCAAGTGGG AACGACTGGG CACTGCCACC ACCAGAAAGC TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC ACAACCACCT GTCCCTGCCT CAGTTCCCTT TTATGTAACA TGAAGTCGTT GTGAGGGTTA AAGGCAGTAA CAGGTATAAA GTACTTAGAA AAGCAAAGGG TGCTACGTAC

ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT ACTATAAGGA AAAGACACTG AGGTCTAGAA ATAGCTCCGT GGAGCAGAAT CAGTATTGGG AGCCGGTGGC GGTGTGAAGC ACCAGTGTCT GGCACACAGT AGGTGCTCAT TGGCTCCCTT CCACCTGTCA TTCCCACCAC CCTGAGGCCC CAACCGCCAC ACACACAGGA GCATTTGGAG AGAAGGCCAT GTCTTCAAAG TCTGATTTGT GATGAGGCAG AGGAAGATAT TTCTAATCGG TCTTGCCCAG AGGATCACAG TGCTGAGACC CCCCACCACC AGCCGGTACC TGGGAAGGGG GAGAGTGCAG GCCTGCTCAG GGACTGTTCC TGTCTCAGCA ACCAAGGGAT TGTTCCTGTC AATCAATGGT TTATTGGAAG GTGGCCCAGT ATGAGCCCTA GAAGAGTGTG AAAAGGAATG GCAATGGTGT TCACCATCGG CAGTGCCAGG GCAGCACTCA TTCACTTGAT AAATGAATAT TTATTAGCTG GTTGGAGAGC TAGAACCTGG

AGAGCTAGAA CCTGGAGAAC TAGAACCTGG AGGGCTAGAA CCTGGAGAGG CTAGAACCAA GAAGGGCTAG AACCTGGAGG GGCTAGAACC TAGAGAAGCT AAAACCTGAG CTAGAAGCTG GAGGACTAGA ACCTGGAGGG CTGGAATCTG AAGGGCTAGA ACCTGGAGGG CTGGAATCTG GAGAGCTAGA ACCTGGAGGG CTAGAACCTG GAGGGCTAGA ACCTAGAAGG GCTAGAACCT GGAGGGCTGG AATCTGGAGA GCTAGAACCT GGAGGGCTAG AACCTGGAGG GCTAGAACCT AGAAGGGCTA GAACCTGGAG GGCTAGAACC TGGCAGGTTA GAACCTAGAA GGGCTAGAAC CTGGAGAGCC AGAACCTGGA GGGCTAGAAC CTGGAAGGGC TAGAACCTGT AGAGCTAGAA CATGGAGAGC TAGAACCCGG CAGGCTAGAA CCTGGCAAGC TAGAACCTGG AGGGAATGAA CCTGGAGGGC TAGAACCTGG

AGAATGAGAA AAATTTACAT GGCAAAGAGC CCATAAATCC TGACCAATCC AACTCTGAAT TTTAAAGCAA AAGCGTGAAA AAAAAGATTC CCTCCTTACC CCCAACCCAC TCTTTTTTCC CACCACCCAC TCTCCTCTGC CTCAGTAAGT ATCTGGAGGA AGAAAACAGG TGAAAGAAGA AGTAAAAACC ATTTAGTATT AGTATTAGAA TGAAGTCAAA CTGTGCCACA CATGGTGAAT GAAAAAAAAA AAAAAGAGGC TGTGTTTTGT CACACAGGGC AGTCATTCAG CACCAGAGCA CGTGATGGTC TGAGACTCTC TTAGGAGCAG AGCTCTGCCG CAATGGCCAT GTGGGGATCC ACACCTGGTC TGAGGGGCAA CTGAGTCTGC GGGAGAAGAG CGGCCCTATG CATGGTGTAG ATGCCCTGAT AAAGAACATC TGTCCTGTGA AAGACTCAAT GAGCTGTTAT GTTGTAAACA GGAAGCATTT CACATCCAAA CGAGAAAATC ATGTAAACAT GTGTCTTTTC TGTAGAGCAT AATAAATGGA

TGAGGTTTTT GCAAAAAAAA AAAAAAAAA -3' (FRAG NO 2275) (SEQ ID NO 11822)

5'- GAGCTCTTCA ATATTTTAGT GAAAGCTATA GATGAGGCTC CATAGGGGAT AAAGCACAGA CACACCTTTT CAGAGGGCTT GTGGACTCTG GGCAGCCTGT CCATAGACCT CTGTCCCCAA CTGGCAAGTC AGGAAACTCC AGATTAAGGA GCCCCAATGT GGTTGAACAG CCAGGTGCAC AGATGAGTCA ACCACACAGC CAGGCCAGGG AGGGCCTTCA CTCAAGAGCC TACAGCCAGT TCACAGCCAA GCCAGGGCTA GCGCCAGGCC ACCCATAAAC TGATCTGAGA CTCTGTTTCC CTGTCTCCAT GATGATGGGA TCAGGCTTGA TTGCTGGTTT GTAGGCTTGT TATGAATCAA GTCACAGGGA AGAGGAGCTG ATGGGCTGGG GGGACGTCCT CTGGCCCTCC TGTCTCTTCC CCAGATCCAC

TGGGCCCACT CTTATCTGTT CTCTTCTGAA GGAAGGGTTT TAAGGCTTCA AAAAAAAATG TTTTGAAAGT CCCTGCCCTT TCCAGCTCCT ACCGTCTCAG CCCTGGGAGT GTAAAGTGCT GCAGATAGTT AGTAAGTCTT TGAGCAAAAC TGAGAAAGCC AGCCTGAGCC TTGACATGGG AGAAACCTCC GCCATACATC TCCGAAGAAA CGGCCGCGTG TCTCAGGGGA GCGCAAACAC CCGTACCCAG GAAACAGGAC AGCTTCTGCC ACTGTCGCCC TTGGGAGCCG TACGTGGCAT GACAAAGAAA TCCCAGGACT CCGCCTGCCC ACCTGGCCAC CCTCTGTTTA CACCTTCCGC GTAAACGCCC ACTGTTTACA TCCAAAACTC AGACACAAAA TAACCACCTC AAGAAGATAA ATAATGATAA GAAATAAATG TTACGCGAGG CAAATTTATT CACATGGGGC TTCCCAGGCC ACTTTGTGGT CAGCCGGGAG GGACGTTTTT GCCGTCCCAC GACTCCAACG GGCAGCCGGG CCTACGCAAA

CATGGAAATC TTCCAAGAGC CTCCCTGGCC CCCAGGGCTC AGAGGGTGGC AGAGCGGAGA GCGAAGGTGG CCGCAGCCTT CCCGGCCCCA CAGCCAGCCT GGCTCCAGCT GGGCAGGAGT GCAGAGCTCA GCTGGAGGCG AGGGGGAAGT GCCCAGGAGG CTGATGACAT CACTACCCAG CCCTTCAAAG ATGAGCTGTT CCCGCCGCCA CTCCAGCTCT GGCTTCTGGG CTCCGAGGAG GGGTGGGGAC GGTGGTGACG GTGGGGACAT CAGGCTGCCC CGCAGTACCA GGGAGCGACT GAAGTGCCCA TGCCGCTTGC TCCGGAGAAG GTGGGTGCCG GGCAGGGGCT GCTCCAGCCG CCTCACCTCT GCTGGGAGGA CAAACTGTCC CAGCACAGAG GGAGGGAGGG AGGGCAGGCA GCGGGGAGAA GTTTCCCTGT GGTCGTGGGG AGTTGGGAAA AGTTCCCTTC CTTCCGGAGG GAGG-3' (FRAG NO 2275) (SEQ D NO 11821)

5'- GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG GCTCCGAGGA GGGGTGGGGA CGGTGGTGAC GGTGGGGACA TCAGGCTGCC CCGCAGTACC AGGGAGCGAC TGAAGTGCCC ATGCCGCTTG CTCCGGAGAA GGTGGGTGCC GGGCAGGGGC TGCTCCAGCC GCCTCACCTC TGCTGGGAGG ACAAACTGTC CCAGCACAGA GGGAGGGAGG GAGGGCAGGC AGCGGGGAGA AGTTTCCCTG TGGTCGTGGG GAGTT -3' (FRAG NO 2275) (SEQ DD NO 11820)

5'- GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG GCTCCGAGGA GGGGTGGGGA CGGTGGGGAC ATCAGGCTGC CCCGCAGTAC CAGGGAGCGA CTGAAGTGCC CATGCCGCTT GCTCCGGAGA AGGTGGGTGC CGGGCAGGGG CTGCTCCAGC CGCCTCACCT CTGCTGGGAG GACAAACTGT CCCAGCACAG AGGGAGGGAG GGAGGGCAGG CAGCGGGGAGAAGTTTCCCT GTGGTCGTGG GGAGTT-3' (FRAGNO 2275) (SEQ DD NO 11819) 5'- ATGTTCTCTC CCTGGAAGAT ATCAATGTTT CTGTCTGTTC GTGAGGACTC CGTGCCCACC ACGGCCTCTT TCAGCGCCGA CATGCTCAAT GTCACCTTGC AAGGGCCCAC TCTTAACGGG ACCTTTGCCC AGAGCAAATG CCCCCAAGTG GAGTGGCTGG GCTGGCTCAA CACCATCCAG CCCCCCTTCC TCTGGGTGCT GTTCGTGCTG GCCACCCTAG

AGAACATCTT TGTCCTCAGC GTCTTCTGCC TGCACAAGAG CAGCTGCACG GTGGCAGAGA TCTACCTGGG GAACCTGGCC GCAGCAGACC TGATCCTGGC CTGCGGGCTG CCCTTCTGGG CCATCACCAT CTCCAACAAC TTCGACTGGC TCTTTGGGGA GACGCTCTGC CGCGTGGTGA ATGCCATTAT CTCCATGAAC CTGTACAGCA GCATCTGTTT CCTGATGCTG GTGAGCATCG ACCGCTACCT GGCCCTGGTG AAAACCATGT CCATGGGCCG GATGCGCGGC GTGCGCTGGG CCAAGCTCTA CAGCTTGGTG ATCTGGGGGT GTACGCTGCT CCTGAGCTCA CCCATGCTGG TGTTCCGGAC CATGAAGGAG TACAGCGATG AGGGCCACAA CGTCACCGCT TGTGTCATCA GCTACCCATC CCTCATCTGG GAAGTGTTCA CCAACATGCT CCTGAATGTC GTGGGCTTCC TGCTGCCCCT GAGTGTCATC ACCTTCTGCA CGATGCAGAT CATGCAGGTG CTGCGGAACA ACGAGATGCA

GAAGTTCAAG GAGATCCAGA CGGAGAGGAG GGCCACGGTG CTAGTCCTGG TTGTGCTGCT GCTATTCATC ATCTGCTGGC TGCCCTTCCA GATCAGCACC TTCCTGGATA CGCTGCATCG CCTCGGCATC CTCTCCAGCT GCCAGGACGA GCGCATCATC GATGTAATCA CACAGATCGC CTCCTTCATG GCCTACAGCA ACAGCTGCCT CAACCCACTG GTGTACGTGA TCGTGGGCAA GCGCTTCCGA AAGAAGTCTT GGGAGGTGTA CCAGGGAGTG TGCCAGAAAG GGGGCTGCAG GTCAGAACCC ATTCAGATGG AGAACTCCAT GGGCACACTG CGGACCTCCA TCTCCGTGGA ACGCCAGATT CACAAACTGC AGGACTGGGC AGGGAGCAGA CAGTGAGCAA ACGCCAGCAG GGCTGCTGTG AATTTGTGTA AGGATTGAGG GACAGTTGCT T -3' (FRAG NO 2275) (SEQ DD NO 11818)

5'- ATGTTCTCTC CCTGGAAGAT ATCAATGTTT CTGTCTGTTT GTGAGGACTC CGTGCCCACC ACGGCCTCTT TCAGCGCCGA CATGCTCAAT GTCACCTTGC AAGGGCCCAC TCTTAACGGG ACCTTTGCCC AGAGCAAATG CCCCCAAGTG GAGTGGCTGG GCTGGCTCAA CACCATCCAG CCCCCCTTCC TCTGGGTGCT GTTCGTGCTG GCCACCCTAG AGAACATCTT TGTCCTCAGC GTCTTCTGCC TGCACAAGAG CAGCTGCACG GTGGCAGAGA TCTACCTGGG GAACCTGGCC GCAGCAGACC TGATCCTGGC CTGCGGGCTG CCCTTCTGGG CCATCACCAT CTCCAACAAC TTCGACTGGC TCTTTGGGGA GACGCTCTGC CGCGTGGTGA ATGCCATTAT CTCCATGAAC CTGTACAGCA GCATCTGTTT CCTGATGCTG GTGAGCATCG ACCGCTACCT GGCCCTGGTG AAAACCATGT CCATGGGCCG GATGCGCGGC GTGCGCTGGG CCAAGCTCTA CAGCTTGGTG ATCTGGGGGT

GTACGCTGCT CCTGAGCTCA CCCATGCTGG TGTTCCGGAC CATGAAGGAG TACAGCGATG AGGGCCACAA CGTCACCGCT TGTGTCATCA GCTACCCATC CCTCATCTGG GAAGTGTTCA CCAACATGCT CCTGAATGTC GTGGGCTTCC TGCTGCCCCT GAGTGTCATC ACCTTCTGCA CGATGCAGAT CATGCAGGTG CTGCGGAACA ACGAGATGCA GAAGTTCAAG GAGATCCAGA CGGAGAGGAG GGCCACGGTG CTAGTCCTGG TTGTGCTGCT GCTATTCATC ATCTGCTGGC TGCCCTTCCA GATCAGCACC TTCCTGGATA CGCTGCATCG CCTCGGCATC CTCTCCAGCT GCCAGGACGA GCGCATCATC GATGTAATCA CACAGATCGC CTCCTTCATG GCCTACAGCA ACAGCTGCCT CAACCCACTG GTGTACGTGA TCGTGGGCAA GCGCTTCCGA AAGAAGTCTT GGGAGGTGTA CCAGGGAGTG TGCCAGAAAG GGGGCTGCAG GTCAGAACCC ATTCAGATGG

AGAACTCCAT GGGCACACTG CGGACCTCCA TCTCCGTGGA ACGCCAGATT CACAAACTGC AGGACTGGGC AGGGAGCAGA CAGTGAGCAA ACGCCAGCAG GGCTGCTGTG AATTTGTGTA AGGATTGAGG GACAGTTGCT T -3' (FRAG NO 2275) (SEQ ID NO 11817)

5'- TGATCCTATC ACAACCTGAG AGTAGTTTTT ACTCCATTTA CAGGTGAGGT CATTGTGGTT CAAGGACGTT AAGTAACTTC CCCAGCTCAC ACGGCTTATA AGTAAGGCAG CCAGGATGTG AACCCAGTAG GACTATCTGG CTGCAAAGTC CCCACCCTCC CTCGCCATCT GTATCCTCCA ATCATCTTCA GTGCTTTGCT GATAGAAGGT ACGGAAATAC GATGCCACAG ACTGTCCAGG AAGACAGAAA CTAGGCAGAT GGGCTGGCCA TGGTCTCCAA GCCAGACTGG AATCTCCAGG TCTGGAATGA TATCATTTTT

CTCTTTTAAT AAATTAACTC ACCCACCACA CGGCTTTGAG AGGCTCAAAG GTGACCAACT CCCTTGGGAG GGCCCCGGTT GATAAGGAAG GAATGTGAAT CCTCCCATCA CGGAAGCTTC AAGGAGGTCA AGGGTCCAAC ACTTGAGATT GTTAGTGCTG TTGGTGGATA CTGCAGAATA TCCAGTGGAG CCTCAGATGA AGAACATGAG GCCCCGTTTA GATCCAAGGA TCAGAGGGGG CTCTGTAAGA CCCAGGGGAG TCAGGTGCAC TGGAGCGCGG GCTGCAGAAA ACAGCCTGAG CTCCACCTCG GCTTCTCCTT GCCCTGGCTG GTTGTCCTTA ACCCCTGTCT CCTTCTGGAC CAGTTTTTGT CCTTCCCTTG TGACCTGAGG GGTAACAGCC TCTTTTCCAC TTTCTTTCAG CGCCGACATG CTCAATGTCA CCTTGCAAGG GCCCACTCTT AACGGGACCT TTGCCCAGAG CAAATGCCCC CAAGTGGAGT GGCTGGGCTG GCTCAACACC ATCCAGCCCC CCTTCCTCTG GGTGCTGTTC

GTGCTGGCCA CCCTAGAGAA CATCTTTGTC CTCAGCGTCT TCTGCCTGCA CAAGAGCAGC TGCACGGTGG CAGAGATCTA CCTGGGGAAC CTGGCCGCAG CAGACCTGAT CCTGGCCTGC GGGCTGCCCT TCTGGGCCAT CACCATCTCC AACAACTTCG ACTGGCTCTT TGGGGAGACG CTCTGCCGCG TGGTGAATGC CATTATCTCC ATGAACCTGT ACAGCAGCAT CTGTTTCCTG ATGCTGGTGA GCATCGACCG CTACCTGGCC CTGGTGAAAA CCATGTCCAT GGGCCGGATG CGCGGCGTGC GCTGGGCCAA GCTCTACAGC TTGGTGATCT GGGGGTGTAC GCTGCTCCTG AGCTCACCCA TGCTGGTGTT CCGGACCATG AAGGAGTACA GCGATGAGGG CCACAACGTC ACCGCTTGTG TCATCAGCTA CCCATCCCTC ATCTGGGAAG TGTTCACCAA CATGCTCCTG AATGTCGTGG GCTTCCTGCT GCCCCTGAGT GTCATCACCT TCTGCACGAT GCAGATCATG CAGGTGCTGC

GGAACAACGA GATGCAGAAG TTCAAGGAGA TCCAGACGGA GAGGAGGGCC ACGGTGCTAG TCCTGGTTGT GCTGCTGCTA TTCATCATCT GCTGGCTGCC CTTCCAGATC AGCACCTTCC TGGATACGCT GCATCGCCTC GGCATCCTCT CCAGCTGCCA GGACGAGCGC ATCATCGATG TAATCACACA GATCGCCTCC TTCATGGCCT ACAGCAACAG CTGCCTCAAC CCACTGGTGT ACGTGATCGT GGGCAAGCGC TTCCGAAAGA AGTCTTGGGA GGTGTACCAG GGAGTGTGCC AGAAAGGGGG CTGCAGGTCA GAACCCATTC AGATGGAGAA CTCCATGGGC ACACTGCGGA CCTCCATCTC CGTGGAACGC CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTGTTGA

TGTCTCCGGT AAAACACCGG AGACTAATTC CTGCCCTGCC CAATTTTCGA GGGAGCATGG CTGTGAGGAT GGGGTGAACT CACGCACAGC CAAGGACTCC AAAATCACAA CAGCATTACT GTTCTTATTT GCTGCCACAC CTGAGCCAGC CTGCTCCTTC CCAGGAGTGG AGGAGGCCTG GGGGAGGGAG AGGAGTGACT GAGCTTCCCT CCCGTGTGTT CTCCGTCCCT GCCCCAGCAA GACAACTTAG ATCTCCAGGA GAACTGCCAT CCACGTTTGG TGCAATGGCT GAGTGCACAA GTGAGTTGTT GCCCTGGGTT TCTTTAATCT ATCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTTGATAAC AACCTGGAGA CCAGGATTTT ATGGCTCCCC TCACTGATGG ACAAGGAGGT CTGTGCCAAA GAAGAATCAA TAAGCACATA TGAGCACTTC TGTATATCAG TATTGAGCAC TGTAGGCA -3' (FRAG NO 2275) (SEQ ID NO 11816)

5'- CTGCAGAAAA CAGCCTGAGC TCCACCTCGG CTTCTCCTTG CCCTGGCTGG TTGTCCTTAA CCCCTGTCTC CTTCTGGACC AGTTTTTGTC CTTCCCTTGT GACCCTGAGG GGTAACAGCC TCTTTTCCAC TTTCTTTCAG CGCCGACATG CTCAATGTCA CCTTGCAAGG GCCCACTCTT AACGGGACCT TTGCCCAGAG CAAATGCCCC CAAGTGGAGT GGCTGGGCTG GCTCAACACC ATCCAGCCCC CCTTCCTCTG GGTGCTGTTC GTGCTGGCCA CCCTAGAGAA CATCTTTGTC CTCAGCGTCT TCTGCCTGCA CAAGAGCAGC TGCACGGTGG CAGAGATCTA CCTGGGGAAC CTGGCCGCAG CAGACCTGAT CCTGGCCTGC GGGCTGCCCT TCTGGGCCAT CACCATCTCC AACAACTTCG ACTGGCTCTT TGGGGAGACG CTCTGCCGCG TGGTGAATGC CATTATCTCC ATGAACCTGT ACAGCAGCAT CTGTTTCCTG ATGCTGGTGA GCATCGACCG CTACCTGGCC CTGGTGAAAA

CCATGTCCAT GGGCCGGATG CGCGGCGTGC GCTGGGCCAA GCTCTACAGC TTGGTGATCT GGGGGTGTAC GCTGCTCCTG AGCTCACCCA TGCTGGTGTT CCGGACCATG AAGGAGTACA GCGATGAGGG CCACAACGTC ACCGCTTGTG TCATCAGCTA CCCATCCCTC ATCTGGGAAG TGTTCACCAA CATGCTCCTG AATGTCGTGG GCTTCCTGCT GCCCCTGAGT GTCATCACCT TCTGCACGAT GCAGATCATG CAGGTGCTGC GGAACAACGA GATGCAGAAG TTCAAGGAGA TCCAGACGGA GAGGAGGGCC ACGGTGCTAG TCCTGGTTGT GCTGCTGCTA TTCATCATCT GCTGGCTGCC CTTCCAGATC AGCACCTTCC TGGATACGCT GCATCGCCTC GGCATCCTCT CCAGCTGCCA GGACGAGCGC ATCATCGATG TAATCACACA GATCGCCTCC TTCATGGCCT ACAGCAACAG CTGCCTCAAC CCACTGGTGT ACGTGATCGT GGGCAAGCGC TTCCGAAAGA

AGTCTTGGGA GGTGTACCAG GGAGTGTGCC AGAAAGGGGG CTGCAGGTCA GAACCCATTC AGATGGAGAA CTCCATGGGC ACACTGCGGA CCTCCATCTC CGTGGAACGC CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG TCTCCGGTAA AACACCGGAG ACTAATTCCT GNCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC AGGAGTGGAG GAGGCCTGGG OGCAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC TCCGTCCCTG CCCCAGCAAG ACAACTTAGA TCTCCAGGAG

AACTGCCATC CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT CTTTAATCTA TTCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGGAGGT CTGTGCCAAA GAAGAATCCA ATAAGCACAT ATTGAGCACT TOCTGTATAT GCAGTATTGA GCACTGTAGG CAAGAGGGAA GAAAGAGAAG GAGCCATCTC CATCTTGAAG GAACTCAAAG ACTCAAGTGG GAACGACTGG CACTGCCACC ACCAGAAAGC TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC ACAACCACCT GTCCCTGCCT CAGTTCCCTC TTCTGTAACA TGAAGTCGTT GTGAGGGTTA AAGGCAGTAA CAGGTATAAA GTACTTAGAA

AAGCAAAGGG TGCTACGTAC ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT ACTATAAGGA AAAGACACTG AGGTCTAGA -3' (FRAG NO 2275) (SEQ DD NO 11815)

5'- AAATGATAGA CCGTCAATAA TTTGTTAAAT OCTTTTTAAA ATGAATGCTT TAAGCCGGGT GCAGTGCCTC ACATCTGTAA TCCCAGCACT TTGGAGCCGA GCGGGTGGAT TGTGTGAGGT CAGGAGTTCG AGACCAACCT GGCCAACATG GCAAAACCTC ACTCTCTACC AAAAATACAA AAATTAGCCA GGCATGGTGG CAGGCACCTG TGATCCCAGC TACTCAGGAG GCTGAGACAG GAGAATCGCT TGAACCCGGG AGGCAAGGTT GCAGTGAGCC AAGATTACGC CATTGTACTC CAGCCTGGGT

GACAGAGAGA GACTCCGTCT CAAAAAAAAA AAAAAAAAAA AAAAAATTAC GCTTCAAACA CATGATCTCT CACCACTGTT GAATTTTCTT TCTATGAGCC CAGGAGGGCC TCTCAGAGAG GAAAGCTCCT AGGTCTTCCT TTCCCTCTGC AAACTCCCTG CCTTGAAGGT TCAGAAGGAC TGTGCGTGCT CGTTGCATCC TTTGCAAGTG TCCAAACCCT GATCCCAGCT GTGCTTAGGG GTTCCTGCAA ACCTTTTCCA GGTGTTAATT ACCTCCCACT TCATTTCCTG TTTACCAACT CAGCTTTTTG TTTTAGTGTG TTTGAATTCC CTGAACTGAC CGTTGTCTGA TCTCCACCTC CCAACTGAAT TAGGGGAGCT GGCCTTCTGG AAACCCAGGT GCCGGGTGTT GCAGAGTGGC TGAAAGCTGG GATGTGGCAG ATCCGTGGCT ACATTCATGC ACACACACAC ACCCACATAC CCACACATGC ACACACACAC ACACACCCGC ACTCACACAC TTGGACATGC ATAGACCACA GCTTTCCACA

CCCTTCCTAG ACAGGGGTCA CTTGGTATCC TGGAGAGAGT GTGAAGTCCT GGAATGGAAA GAGGGGGGAT TAAGCCCCAC CTCTAGCCAT GGGACTGAGA CAAGTCACCA CCAACCCATC TGCGCCTTGT TTACCTCCTC TGTGAGGCAA GCACAGAGCC CATGCCTGCC CCCCTGGATG GGAGTGATGT GAAACTTGAA GGGCGGTCAG AGCAAGGGTC GGGAATGGAA GGCCCTTGGG AAAAAAGGCC CTTTCAACTA GGGGCACAGA GGAGGCCCTG GGCTGAGAAC TTGACAGCAC CTTGTAATTG GTAAGCCAAG CCCGAAGGGA CTGGAAATAC TCAGATGTGT CTGTCTCCCT TATTAGGTTC AAAGTCCCTC AAGACCCTGT CTCCATCACA GTGCTCCAGT CCAGACCCCT CCTCTGAGCT CCAGACCCTG CTGGACCCAA CCAGCCCTAT GGGGTCGCAT CCCCACCTGC CTGGAATTCT CCAAAGAACC TCCCCTTTAA CAGTTCCAGC CTTTAACAGT TCCAGTCTAA

ACACATGACC TTTCTCCTCT AAATCAGCCC CCCATCTCTG CCTTTGCAGG AGATGGAAGC CATGACACCT GCCTCGCCCC TGTCCTCACC CCATCCATGT CCAATCAAGC ACTAGGCATG TCAGGTTTAC CCTCTAAACT CCTCTGGAAT CCAGTCTCTC AGTCTCCATC ATCCCAGGTC GAAGCTAATG GGCTAACTGG TCCTTGCTTC CACTCTACCC CCACTGCAGT CCTGACTTCC TGAGCAGCAG CCAGGGCCTA ATCGATATTC ACACCAAGCG CCAACCTGAC TGAGATATCC TCCTGCACCA TCATCCCTCC ACCCTGTTTA GTTCTGCTCA CCCTCAGTGT TCTCATCAAT AATCCACTCC CCTCACAGGC GCGTTTGGGA CCCCATGTTC TATGCTCTCA CAGGACCTTT TGCTTGATTT TTCACTGTAC TTAGGTCAGT TTGCAGTTAT TAAGTGACTG AGCAATGTCT GGCTTCTCCA GTAGACTGTC AGCTCCTAGC CATTGTATAC CTAGCACCGC TGTGTGGGAG CACGTGACAA

ACGTCCAGTG AGTCAGGGAC TCAGCAGTCT CCATTTCTCC GCCCTGCTGG AGAATGCGTG TATTTGGCAA TCCCCAGCCC CTGTGCCATC TAACCATCTT TTCTTCTCTG TTCAGCCCAG GTGTGGCCTC ACTCACATCC CACTCTGAGT CCAAATGTTC TCTCCCTGGA AGATATCAAT GTTTCTGTCT GTTCGTGAGG ACTCCGTGCC CACCACGGCC TCTTTCAGGT GAGTCAAAGG GATTCCTCAG TTCACTAGTT AGGGGAGGTG GGCAGACACC CTGGAGAACT CCCTGGAAAG CTCAACTCTC ATGCCCCGGA CAACAGTTGA AGGAACCATG GTGATGTTAA GCCCAAAGAC AAAACCTCTC AGGTGTCCAA GTCCCTGTTG GAATCTTGGG AGCAGAGGGA ATGTTCTGTG GTCTAGAGGA AGAGGGGCTC AGGGAGGAGA AGGGCACATT CCTGGTTGTT ATATGTTTCT ATCTATCCCA GATGAACTTG GAAGTGAAGG GAAGAGAGTT AAACATTAAA GTAAATACCC AGTGGATCAG ACAGCAATGT GCCAGATTGC CTTGGAAACA AAATATCTCC AACACATGGC TGACATTTGG TGGGAGATCA GAACACCCTA AAGAGAGAAT TTAAGGGGAG GGGGAGGAGG ACCTGAGCCA GAGTAGAAGC AGAGGATAGG GAGATCTGTT CTTGGGGACA GCATTTGCAA GAAACAAGGC TGAGGGGTCC ACTCCAACCT CTCCACCCTG CTGCAGGTGC TGCCTATGAT GAAGATGAGC AGATGGCCAT CTCAGCTGGG GCCACAGTGC ACTGGACCTA TAGTTTCCAA TTCCGCACTC AGCAGGCATC TTTCTGATGA TCCGATGGCT TCTCAGAGCC AGGGATGGGC CAGGATCCAT CCCCTTGGCT ACTGTCTTGC TGAGAAATTT ATAAGCAGCA TCTGGTGCTA TACTTTGGTC

TCTAGTGAGT TAGCTCATGA AAGATGATAG ACTCTCCAAG CCAGGGGTAT GCAGGAAATG GGTTTTCTGT AGCTACAGAA ATGGGGTTGA GGGTTGGACC AAGGGACTAC CCAGGGGAAG TCTTACCTTC AGAGGACTCT GGAAAGGAGG CTGCAAGTTT TCATGGGTCA AGAATTCAGA GCCCAGTAGA GACAGCTTAT CTCTGTTCCA AGATGTCTGG GGCCTTGGTT GGAAGATTCA AAGGCTAGGA AACCAGGAGC CACCAAAAGC GTAACTGGGG CCAGAGGATC CACTTTCAAG GTGGCAAGTT GGTTCCCCCC ATGTGGCTGC TTGAGTATCC TCACATGGCG GCTCACATCC TTCCAAGTAA GCAATGCAAA AGGCCAAGAA AGATGCTGCA AAGATGTTAT GACCTAGCCT CAGAAATCAC ACACCATCCC TGCCACCATT AGTAAGAAGT CCAGCCCACG TCCAGGAGAA GAGGAAGCAG ATTCCTCCTT TTGAAATGAA GAATATCAAG TAATTCGGGG GGCATATGAA AGCCACCACA

CACCACAGGG ATCTTTTTAG AGCATACTTC TTATACCATC ACTGTAGTTC CTTAAGACTC AGGGGCAAAG CCTCACTTCC TTAGCACCCA GTGAAGACCA CGCTTACTCC CTCACTCAAC CTCTTGCTAC TTCCCACCTC TCCTGTCCAA CATCTAGTGT CACTTTCCAG AACATACCAA CAGCTTCCCC AGTTCTGTGC CTCTGCTCAG GCTGTTCCCC CTGCCTGGTC CACTTGTCCT CCTTCTTGTC CGGTCAAAAT GCTTCTTATC CTTCAAGACC CAGCTCTAGA GTCACCTCCA ACCCCTTACC CACCAGCCCC CTCTCCAAGT CTGTGTCCCA CAACCCCCCT GCTCCCTCCA GGGCACCCTC CACCCTCTGG GCCACAGTTG TCAGGAGTCA GGCAGGGCAG GGGCCGGGTG GTGTCTTCTT TGTGTTCTTG CACTCAGGGC AGAGCTCAGC ACAGAGCAGA CGCTCAAAAA ACATTTAAAG GATAGAAGCA TTGATTTGTG GGTCCCCCAG TCTGGCTCCA GGATGCCAGC CAGCTGCTCC

TAGAAGCAAA CGGACTTTTC CTGGGAAATC CCAGAGGTGA TGATCAGTAA TCTCTCCCGT GACTCGTAGT TCAGCTCTTC CTCCATGAGC CTGACTATCA GTGGACCTTC CAGAAAGAGC CCCTTTTCCT TCTCTCACCC ACAGCACAGG GCACTGGGAA AATGCCCAAT GAGTCCTGCC TCTGGGTTGT GCTTTGGACT TTTCAGTGTG TCTCGCATCC ACTCTTCAAC TTGAATGTTG CAACAGCCAT GAAAAAAGAA ATGCAAAGCG ATTCAGGATG AGAGCAATAC CCTACTCCAA AGAAGGCAAC ATAGAAGCTC AGAGAGATCA AGCAATTTGC CCAAGACCAC ACAGCTAGGA GTGGAACTCA TGGCTGTCCA AGCCCCATGC CTCTGCTGAA GGTAGAGATG AATTACAGCA ACAAGTCTAG AAAGGTGCCT GCCCTATGGT CTGTGAGTCT TGCCTAAGAA TGAAAGAGGA GCCAGTGGGT TAAAGATGAG GTCACCAACA ACGGTGGTGT TGGAGTTTAC CACTGATAAT AAGGGTGCAA

AATGTAAATT ACTAATGTTT ATTGAGCCTA GTGCAGTGCG TGGGGCATTT TGCACATTGT CTCTGATCCC TATGACAACC CTGAGAGGTA GTGGTTTTAA CTGCCATGTT ACAGGTGAGG TCATTGTGGT TCAAGGACGT TAAGTAACTT CCCCAGCGTG ACACGGCTTA TAAGTAAGGC AGCCAGGATG TGAACCCAGT AGGACTATCT GGCTGCAAAG TCCCCACCCC CCTCGCCATC TGTATCCTCC AATCACTTCA GTGCTTTGCT GCATAGAAGG TAACGGAAAT CACGATGCCA CAGACTGTCC AGGAAGACAG AAACTAGGCA GATGGGCTGG CCATGGTCTC CAAGCCAGAC TGGAATCTCC AGGTCTGGAA TGATATCATT TTTCTCTTTT AATAAATTAA CTCACCCACC ACACGGCTTT GAGAGGCTCA AAGTTGACCA ACTCCCTTGG GAGGGCCCCG GTTGATAAGG AAGGAACGTG AATCCTCCCA TCACGGAAGC TTCAAGGAGG TCAAGGGTCC AACACTTGAG ATTGTTAGTG

CTGTTGGTGG ATACTGGCCA AGGAAATATC CCAGTGGAGC CTCGAGATGA AGAACATGAG GCCCCCGTTT AGAACCAAGG ATCAGAGGGG GCTCTGTAAG ACCCAGGGGA GTCAGGTGCA CTGGAGCGCG GGCATGCAGA AAACAGCCTG AGCTCCACCT CGGCTTCTCC TTGTCCTGGC TGGTTGTCCT TAACCCCTGT CTCCTTCTGG ACCAGTTTTT GTCCTTCCCT TGTGACCGCT GAGGGGTAAC AGCCTCTTTC CACTTTCTTT CAGCGCCGAC ATGCTCAATG TCACCTTGCA AGGGCCCACT CTTAACGGGA CCTTTGCCCA GAGCAAATGC CCCCAAGTGG AGTGGCTGGG CTGGCTCAAC ACCATCCAGC CCCCCTTCCT CTGGGTGCTG TTCGTGCTGG CCACCCTAGA GAACATCTTT GTCCTCAGCG TCTTCTGCCT GCACAAGAGC AGCTGCACGG TGGCAGAGAT CTACCTGGGG AACCTGGCCG CAGCAGACCT GATCCTGGCC TGCGGGCTGC CCTTCTGGGC

CATCACCATC TCCAACAACT TCGACTGGCT CTTTGGGGAG ACGCTCTGCC GCGTGGTGAA TGCCATTATC TCCATGAACC TGTACAGCAG CATCTGTTTC CTGATGCTGG TGAGCATCGA CCGCTACCTG GCCCTGGTGA AAACCATGTC CATGGGCCGG ATGCGCGGCG TGCGCTGGGC CAAGCTCTAC AGCTTGGTGA TCTGGGGGTG TACGCTGCTC CTGAGCTCAC CCATGCTGGT GTTCCGGACC ATGAAGGAGT ACAGCGATGA GGGCCACAAC GTCACCGCTT GTGTCATCAG CTACCCATCC GTCATCTGGG AAGTGTTCAC CAACATGCTC CTGAATGTCG TGGGCTTCCT GCTGCCCCTG AGTGTCATCA CCTTCTGCAC GATGCAGATC ATGCAGGTGC TGCGGAACAA CGAGATGCAG AAGTTCAAGG AGATCCAGAC GGAGAGGAGG GCCACGGTGC TAGTCCTGGT TGTGCTGCTG CTATTCATCA TCTGCTGGCT GCCCTTCCAG ATCAGCACCT TCCTGGATAC GCTGCATCGC

CTCGGCATCC TCTCCAGCTG CCAGGACGAG CGCATCATCG ATGTAATCAC ACAGATCGCC TCCTTCATGG CCTACAGCAA CAGCTGCCTC AACCCACTGG TGTACGTGAT CGTGGGCAAG CGCTTCCGAA AGAAGTCTTG GGAGGTGTAC CAGGGAGTGT GCCAGAAAGG GGGCTGCAGG TCAGAACCCA TTCAGATGGA GAACTCCATG GGCACACTGC GGACCTCCAT CTCCGTGGAA CGCCAGATTC ACAAACTGCA GGACTGGGCA GGGAGCAGAC AGTGAGCAAA CGCCAGCAGG GCTGCTGTGA ATTTGTGTAA GGATTGAGGG ACAGTTGCTT TTCAGCATGG GCCCAGGAAT GCCAAGGAGA CATCTATGCA CGACCTTGGG AAATGAGTTG ATGTCTCCGG TAAAACACCG GAGACTAATT CCTGCCCTGC CCAATTTTGC AGGGAGCATG GCTGTGAGGA TGGGGTGAAC TCACGCACAG CCAAGGACTC CAAAATCACA ACAGCATTAC TGTTCTTATT

TGCTGCCACA CCTGAGCCAG CCTGCTCCTT CCCAGGAGTG GAGGAGGCCT GGGGGCAGGG AGAGGAGTGA CTGAGCTTCC CTCCCGTGTG TTCTCCGTCC CTGCCCCAGC AAGACAACTT AGATCTCCAG GAGAACTGCC ATCCAGCTTT GGTGCAATGG CTGAGTGCAC AAGTGAGTTG TTGCCCTGGG TTTCTTTAAT CTATTCAGCT AGAACTTTGA AGGACAATTT CTTGCATTAA TAAAGGTTAA GCCCTGAGGG GTCCCTGATA ACAACCTGGA GACCAGGATT TTATGGCTCC CCTCACTGAT GGACAAGGAG GTCTGTGCCA AAGAAGAATC CAATAAGCAC ATATTGAGCA CTTGCTGTAT ATGCAGTATT GAGCACTGTA GGCAAGAGGG AAGAAAGAGA AGGAGCCATC TCCATCTTGA AGGAACTCAA AGACTCAAGT GGGAACGACT GGGCACTGCC ACCACCAGAA AGCTGTTCGA TGAGACGGTC GAGCAGGGTG CTGTGGGTGA TATGGACAGC AGAAGGGGGA

GCCAGGTTCC AGCTCACCAA TACTATTGCA CACCACCTGT CCTGCCTC-3' (FRAG NO 2275) (SEQ D NO 244S)

5'-CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG TCTCCGGTAA AACACCGGAG ACTAATTCCT GCCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC AGGAGTGGAG GAGGCCTGGG GGGAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC TCCGTCCCTG CCCCAGCAAG ACAACTTAGA TCTCCAGGAG AACTGCCATC

CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT CTTTAATCTA TTCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGAGGTC TGTGCCAAAG AAGAATCCAA TAAGCACATA TTGAGCACTT GCTGTATATG CAGTATTGAG CACTGTAGGC AAGACCCAAG AAAGAGAAGG AGCCATCTCC ATCTTGAAGG AACTCAAAGA CTCAAGTGGG AACGACTGGG CACTGCCACC ACCAGAAAGC TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC ACAACCACCT GTCCCTGCCT CAGTTCCCTT TTATGTAACA TGAAGTCGTT GTGAGGGTTA AAGGCAGTAA CAGGTATAAA GTACTTAGAA AAGCAAAGGG TGCTACGTAC

ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT ACTATAAGGA AAAGACACTG AGGTCTAGAA ATAGCTCCGT GGAGCAGAAT CAGTATTGGG AGCCGGTGGC GGTGTGAAGC ACCAGTGTCT GGCACACAGT AGGTGCTCAT TGGCTCCCTT CCACCTGTCA TTCCCACCAC CCTGAGGCCC CAACCGCCAC ACACACAGGA GCATTTGGAG AGAAGGCCAT GTCTTCAAAG TCTGATTTGT GATGAGGCAG AGGAAGATAT TTCTAATCGG TCTTGCCCAG AGGATCACAG TGCTGAGACC CCCCACCACC AGCCGGTACC TGGGAAGGGG GAGAGTGCAG GCCTGCTCAG GGACTGTTCC TGTCTCAGCA ACCAAGGGAT TGTTCCTGTC AATCAATGGT TTATTGGAAG GTGGCCCAGT ATGAGCCCTA GAAGAGTGTG AAAAGGAATG GCAATGGTGT TCACCATCGG CAGTGCCAGG GCAGCACTCA TTCACTTGAT AAATGAATAT TTATTAGCTG GTTGGAGAGC TAGAACCTGG

AGAGCTAGAA CCTGGAGAAC TAGAACCTGG AGGGCTAGAA CCTGGAGAGG CTAGAACCAA GAAGGGCTAG AACCTGGAGG GGCTAGAACC TAGAGAAGCT AAAACCTGAG CTAGAAGCTG GAGGACTAGA ACCTGGAGGG CTGGAATCTG AAGGGCTAGA ACCTGGAGGG CTGGAATCTG GAGAGCTAGA ACCTGGAGGG CTAGAACCTG GAGGGCTAGA ACCTAGAAGG GCTAGAACCT GGAGGGCTGG AATCTGGAGA GCTAGAACCT GGAGGGCTAG AACCTGGAGG GCTAGAACCT AGAAGGGCTA GAACCTGGAG GGCTAGAACC TGGCAGGTTA GAACCTAGAA GGGCTAGAAC CTGGAGAGCC AGAACCTGGA GGGCTAGAAC CTGGAAGGGC TAGAACCTGT AGAGCTAGAA CATGGAGAGC TAGAACCCGG CAGGCTAGAA CCTGGCAAGC TAGAACCTGG AGGGAATGAA CCTGGAGGGC TAGAACCTGG

AGAATGAGAA AAATTTACAT GGCAAAGAGC CCATAAATCC TGACCAATCC AACTCTGAAT TTTAAAGCAA AAGCGTGAAA AAAAAGATTC CCTCCTTACC CCCAACCCAC TCTTTTTTCC CACCACCCAC TCTCCTCTGC CTCAGTAAGT ATCTGGAGGA AGAAAACAGG TGAAAGAAGA AGTAAAAACC ATTTAGTATT AGTATTAGAA TGAAGTCAAA CTGTGCCACA CATGGTGAAT GAAAAAAAAA AAAAAGAGGC TGTGTTTTGT CACACAGGGC AGTCATTCAG CACCAGAGCA CGTGATGGTC TGAGACTCTC TTAGGAGCAG AGCTCTGCCG CAATGGCCAT GTGGGGATCC ACACCTGGTC TGAGGGGCAA CTGAGTCTGC GGGAGAAGAG CGGCCCTATG CATGGTGTAG ATGCCCTGAT AAAGAACATC TGTCCTGTGA AAGACTCAAT GAGCTGTTAT GTTGTAAACA GGAAGCATTT CACATCCAAA CGAGAAAATC ATGTAAACAT GTGTCTTTTC TGTAGAGCAT AATAAATGGA

TGAGGTTTTT GCAAAAAAAA AAAAAAAAA-3' (FRAG NO 2275) (SEQ DD NO 11813)

5'- GAGCTCTTCA ATATTTTAGT GAAAGCTATA GATGAGGCTC CATAGGGGAT AAAGCACAGA CACACCTTTT CAGAGGGCTT GTGGACTCTG GGCAGCCTGT CCATAGACCT CTGTCCCCAA CTGGCAAGTC AGGAAACTCC AGATTAAGGA GCCCCAATGT GGTTGAACAG CCAGGTGCAC AGATGAGTCA ACCACACAGC CAGGCCAGGG AGGGCCTTCA CTCAAGAGCC TACAGCCAGT TCACAGCCAA GCCAGGGCTA GCGCCAGGCC ACCCATAAAC TGATCTGAGA CTCTGTTTCC CTGTCTCCAT GATGATGGGA TCAGGCTTGA TTGCTGGTTT GTAGGCTTGT TATGAATCAA GTCACAGGGA AGAGGAGCTG ATGGGCTGGG GGGACGTCCT CTGGCCCTCC TGTCTCTTCC CCAGATCCAC

TGGGCCCACT CTTATCTGTT CTCTTCTGAA GGAAGGGTTT TAAGGCTTCA AAAAAAAATG TTTTGAAAGT CCCTGCCCTT TCCAGCTCCT ACCGTCTCAG CCCTGGGAGT GTAAAGTGCT GCAGATAGTT AGTAAGTCTT TGAGCAAAAC TGAGAAAGCC AGCCTGAGCC TTGACATGGG AGAAACCTCC GCCATACATC TCCGAAGAAA CGGCCGCGTG TCTCAGGGGA GCGCAAACAC CCGTACCCAG GAAACAGGAC AGCTTCTGCC ACTGTCGCCC TTGGGAGCCG TACGTGGCAT GACAAAGAAA TCCCAGGACT CCGCCTGCCC ACCTGGCCAC CCTCTGTTTA CACCTTCCGC GTAAACGCCC ACTGTTTACA TCCAAAACTC AGACACAAAA TAACCACCTC AAGAAGATAA ATAATGATAA GAAATAAATG TTACGCGAGG CAAATTTATT CACATGGGGC TTCCCAGGCC ACTTTGTGGT CAGCCGGGAG GGACGTTTTT GCCGTCCCAC GACTCCAACG GGCAGCCGGG CCTACGCAAA

CATGGAAATC TTCCAAGAGC CTCCCTGGCC CCCAGGGCTC AGAGGGTGGC AGAGCGGAGA GCGAAGGTGG CCGCAGCCTT CCCGGCCCCA CAGCCAGCCT GGCTCCAGCT GGGCAGGAGT GCAGAGCTCA GCTGGAGGCG AGGGGGAAGT GCCCAGGAGG CTGATGACAT CACTACCCAG CCCTTCAAAG ATGAGCTGTT CCCGCCGCCA CTCCAGCTCT GGCTTCTGGG CTCCGAGGAG GGGTGGGGAC GGTGGTGACG GTGGGGACAT CAGGCTGCCC CGCAGTACCA GGGAGCGACT GAAGTGCCCA TGCCGCTTGC TCCGGAGAAG GTGGGTGCCG GGCAGGGGCT GCTCCAGCCG CCTCACCTCT GCTGGGAGGA CAAACTGTCC CAGCACAGAG GGAGGGAGGG AGGGCAGGCA GCGGGGAGAA GTTTCCCTGT GGTCGTGGGG AGTTGGGAAA AGTTCCCTTC CTTCCGGAGG GAGG-3' (FRAG NO 2275) (SEQ ED NO 11812)

5'- GCCCTTCAAA GATGAGCTGT TCCCGCCGCC ACTCCAGCTC TGGCTTCTGG GCTCCGAGGA GGGGTGGGGA CGGTGGTGAC GGTGGGGACA TCAGGCTGCC CCGCAGTACC AGGGAGCGAC TGAAGTGCCC ATGCCGCTTG CTCCGGAGAA GGTGGGTGCC GGGCAGGGGC TGCTCCAGCC GCCTCACCTC TGCTGGGAGG ACAAACTGTC CCAGCACAGA GGGAGGGAGG GAGGGCAGGC AGCGGGGAGA AGTTTCCCTG TGGTCGTGGG GAGTT -3' (FRAG NO 2275) (SEQ ID NO 11811) 5'- AAATGATAGA CCGTCAATAA TTTGTTAAAT GCTTTTTAAA ATGAATGCTT TAAGCCGGGT GCAGTGCCTC ACATCTGTAA TCCCAGCACT TTGGAGCCGA GCGGGTGGAT TGTGTGAGGT CAGGAGTTCG AGACCAACCT GGCCAACATG GCAAAACCTC ACTCTCTACC AAAAATACAA AAATTAGCCA GGCATGGTGG CAGGCACCTG

TGATCCCAGC TACTCAGGAG GCTGAGACAG GAGAATCGCT TGAACCCGGG AGGCAAGGTT GCAGTGAGCC AAGATTACGC CATTGTACTC CAGCCTGGGT GACAGAGAGA GACTCCGTCT CAAAAAAAAA AAAAAAAAAA AAAAAATTAC GCTTCAAACA CATGATCTCT CACCACTGTT GAATTTTCTT TCTATGAGCC GAGGAGGGCC TCTCAGAGAG GAAAGCTCCT AGGTCTTCCT TTCCCTCTGC AAACTCCCTG CCTTGAAGGT TCAGAAGGAC TGTGCGTGCT CGTTGCATCC TTTGCAAGTG TCCAAACCCT GATCCCAGCT GTGCTTAOGG GTTCCTGCAA ACCTTTTCCA GGTGTTAATT ACCTCCCACT TCATTTCCTG TTTACCAACT CAGCTTTTTG TTTTAGTGTG TTTGAATTCC CTGAACTGAC CGTTGTCTGA TCTCCACCTC CCAACTGAAT TAGGGGAGCT GGGCTTCTGG AAACCCAGGT GCCGGGTGTT GCAGAGTGGC TGAAAGCTGG GATGTGGCAG

ATCCGTGGCT ACATTCATGC ACACACACAC ACCCACATAC CCACACATGC ACACACACAC ACACACCCGC ACTCACACAC TTGGACATGC ATAGACCACA GCTTTCCACA CCCTTCCTAG ACAGGGGTCA CTTGGTATCC TGGAGAGAGT GTGAAGTCCT GGAATGGAAA GAGGGGGGAT TAAGCCCCAC CTCTAGCCAT GGGACTGAGA CAAGTCACCA CCAACCCATC TGCGCCTTGT TTACCTCCTC TGTGAGGCAA GCACAGAGCC CATGCCTGCC CCCCTGGATG GGAGTGATGT GAAACTTGAA GGGCGGTCAG AGCAAGGGTC GGGAATGGAA GGCCCTTGGG AAAAAAGGCC CTTTCAACTA GGGGCACAGA GGAGGCCCTG GGCTGAGAAC TTGACAGCAC CTTGTAATTG GTAAGCCAAG CCCGAAGGGA CTGGAAATAC TCAGATGTGT CTGTCTCCCT TATTAGGTTC AAAGTCCCTC AAGACCCTGT CTCCATCACA GTGCTCCAGT CCAGACCCCT CCTCTGAGCT CCAGACCCTG CTGGACCCAA CCAGCCCTAT GGGGTCGCAT CCCCACCTGC CTGGAATTCT CCAAAGAACC TCCCCTTTAA CAGTTCCAGC CTTTAACAGT TCCAGTCTAA ACACATGACC TTTCTCCTCT AAATCAGCCC CCCATCTCTG CCTTTGCAGG AGATGGAAGC CATGACACCT GCCTCGCCCC TGTCCTCAGC CCATCCATGT CCAATCAAGC ACTAGGCATG TCAGGTTTAC CCTCTAAACT CCTCTGGAAT CCAGTCTCTC AGTCTCCATC ATCCCAGGTC GAAGCTAATG GGCTAACTGG TCCTTGCTTC CACTCTACCC CCACTGCAGT CCTGACTTCC TGAGCAGCAG CCAGGGCCTA ATCGATATTC ACACCAAGCG CCAACCTGAC TGAGATATCC TCCTGCACCA TCATCCCTCC ACCCTGTTTA

GTTCTGCTCA CCCTCAGTGT TCTCATCAAT AATCCACTCC CCTCACAGGC GCGTTTGGGA CCCCATGTTC TATGCTCTCA CAGGACCTTT TGCTTGATTT TTCACTGTAC TTAGGTCAGT TTGCAGTTAT TAAGTGACTG AGCAATGTCT GGCTTCTCCA GTAGACTGTC AGCTCCTAGC CATTGTATAC CTAGCACCGC TGTGTGGGAG CACGTGACAA ACGTCCAGTG AGTCAGGGAC TCAGCAGTCT CCATTTCTCC GCCCTGCTGG AGAATGCGTG TATTTGGCAA TCCCCAGCCC CTGTGCCATC TAACCATCTT TTCTTCTCTG TTCAGCCCAG GTGTGGCCTC ACTCACATCC CACTCTGAGT CCAAATGTTC TCTCCCTGGA AGATATCAAT GTTTCTGTCT GTTCGTGAGG ACTCCGTGCC CACCACGGCC TCTTTCAGGT GAGTCAAAGG GATTCCTCAG TTCACTAGTT AGGGGAGGTG GGCAGACACC CTGGAGAACT CCCTGGAAAG CTCAACTCTC ATGCCCCGGA CAACAGTTGA

AGGAACCATG GTGATGTTAA GCCCAAAGAC AAAACCTCTC AGGTGTCCAA GTCCCTGTTG GAATCTTGGG AGCAGAGGGA ATGTTCTGTG GTCTAGAGGA AGAGGGGCTC AGGGAGGAGA AGGGCACATT CCTGGTTGTT ATATGTTTCT ATCTATCCCA GATGAACTTG GAAGTGAAGG GAAGAGAGTT AAACATTAAA GTAAATACCC AGTGGATCAG ACAGCAATGT GCCAGATTGC CTTGGAAACA AAATATCTCC AACACATGGC TGACATTTGG TGGGAGATCA GAACACCCTA AAGAGAGAAT TTAAGGGGAG GGGGAGGAGG ACCTGAGCCA GAGTAGAAGC AGAGGATAGG GAGATCTGTT CTTGGGGACA GCATTTGCAA GAAACAAGGC TGAGGGGTCC ACTCCAACCT CTCCACCCTG CTGCAGGTGC TGCCTATGAT GAAGATGAGC AGATGGCCAT CTCAGCTGGG GCCACAGTGC ACTGGACCTA TAGTTTCCAA TTCCGCACTC AGCAGGCATC

TTTCTGATGA TCCGATGGCT TCTCAGAGCC AGGGATGGGC CAGGATCCAT CCCCTTGGCT ACTGTCTTGC TGAGAAATTT ATAAGCAGCA TCTGGTGCTA TACTTTGGTC TCTAGTGAGT TAGCTCATGA AAGATGATAG ACTCTCCAAG CCAGGGGTAT GCAGGAAATG GGTTTTCTGT AGCTACAGAA ATGGGGTTGA GGGTTGGACC AAGGGACTAC CCAGGGGAAG TCTTACCTTC AGAGGACTCT GGAAAGGAGG CTGCAAGTTT TCATGGGTCA AGAATTCAGA GCCCAGTAGA GACAGCTTAT CTCTGTTCCA AGATGTCTGG GGCCTTGGTT GGAAGATTCA AAGGCTAGGA AACCAGGAGC CACCAAAAGC GTAACTGGGG CCAGAGGATC CACTTTCAAG GTGGCAAGTT GGTTCCCCCC ATGTGGCTGC TTGAGTATCC TCACATGGCG GCTCACATCC TTCCAAGTAA GCAATGCAAA AGGCCAAGAA AGATGCTGCA AAGATGTTAT GACCTAGCCT CAGAAATCAC ACACCATCCC

TGCCACCATT AGTAAGAAGT CCAGCCCACG TCCAGGAGAA GAGGAAGCAG ATTCCTCCTT TTGAAATGAA GAATATCAAG TAATTCGGGG GGCATATGAA AGCCACCACA CACCACAGGG ATCTTTTTAG AGCATACTTC TTATACCATC ACTGTAGTTC CTTAAGACTC AGGGGCAAAG CCTCACTTCC TTAGCACCCA GTGAAGACCA CGCTTACTCC CTCACTCAAC CTCTTGCTAC TTCCCACCTC TCCTGTCCAA CATCTAGTGT CACTTTCCAG AACATACCAA CAGCTTCCCC AGTTCTGTGC CTCTGCTCAG GCTGTTCCCC CTGCCTGGTC CACTTGTCCT CCTTCTTGTC CGGTCAAAAT GCTTCTTATC CTTCAAGACC CAGCTCTAGA GTCACCTCCA ACCCCTTACC CACCAGCCCC CTCTCCAAGT CTGTGTCCCA CAACCCCCCT GCTCCCTCCA GGGCACCCTC CACCCTCTGG GCCACAGTTG TCAGGAGTCA GGCAGGGCAG GGGCCGGGTG GTGTCTTCTT TGTGTTCTTG

CACTCAGGGC AGAGCTCAGC ACAGAGCAGA CGCTCAAAAA ACATTTAAAG GATAGAAGCA TTGATTTGTG GGTCCCCCAG TCTGGCTCCA GGATGCCAGC CAGCTGCTCC TAGAAGCAAA CGGACTTTTC CTGGGAAATC CCAGAGGTGA TGATCAGTAA TCTCTCCCGT GACTCGTAGT TCAGCTCTTC CTCCATGAGC CTGACTATCA GTGGACCTTC CAGAAAGAGC CCCTTTTCCT TCTCTCACCC ACAGCACAGG GCACTGGGAA AATGCCCAAT GAGTCCTGCC TCTGGGTTGT GCTTTGGACT TTTCAGTGTG TCTCGCATCC ACTCTTCAAC TTGAATGTTG CAACAGCCAT GAAAAAAGAA ATGCAAAGCG ATTCAGGATG AGAGCAATAC CCTACTCCAA AGAAGGCAAC ATAGAAGCTC AGAGAGATCA AGCAATTTGC CCAAGACCAC ACAGCTAGGA GTGGAACTCA TGGCTGTCCA AGCCCCATGC CTCTGCTGAA GGTAGAGATG AATTACAGCA ACAAGTCTAG AAAGGTGCCT

GCCCTATGGT CTGTGAGTCT TGCCTAAGAA TGAAAGAGGA GCCAGTGGGT TAAAGATGAG GTCACCAACA ACGGTGGTGT TGGAGTTTAC CACTGATAAT AAGGGTGCAA AATGTAAATT ACTAATGTTT ATTGAGCCTA GTGCAGTGCG TGGGGCATTT TGCACATTGT CTCTGATCCC TATGACAACC CTGAGAGGTA GTGGTTTTAA CTGCCATGTT ACAGGTGAGG TCATTGTGGT TCAAGGACGT TAAGTAACTT CCCCAGCGTG ACACGGCTTA TAAGTAAGGC AGCCAGGATG TGAACCCAGT AGGACTATCT GGCTGCAAAG TCCCCACCCC CCTCGCCATC TGTATCCTCC AATCACTTCA GTGCTTTGCT GCATAGAAGG TAACGGAAAT CACGATGCCA CAGACTGTCC AGGAAGACAG AAACTAGGCA GATGGGCTGG CCATGGTCTC CAAGCCAGAC TGGAATCTCC AGGTCTGGAA TGATATCATT TTTCTCTTTT AATAAATTAA CTCACCCACC ACACGGCTTT GAGAGGCTCA

AAGTTGACCA ACTCCCTTGG GAGGGCCCCG GTTGATAAGG AAGGAACGTG AATCCTCCCA TCACGGAAGC TTCAAGGAGG TCAAGGGTCC AACACTTGAG ATTGTTAGTG CTGTTGGTGG ATACTGGCCA AGGAAATATC CCAGTGGAGC CTCGAGATGA AGAACATGAG GCCCCCGTTT AGAACCAAGG ATCAGAGGGG GCTCTGTAAG ACCCAGGGGA GTCAGGTGCA CTGGAGCGCG GGCATGCAGA AAACAGCCTG AGCTCCACCT CGGCTTCTCC TTGTCCTGGC TGGTTGTCCT TAACCCCTGT CTCCTTCTGG ACCAGTTTTT GTCCTTCCCT TGTGACCGCT GAGGGGTAAC AGCCTCTTTC CACTTTCTTT CAGCGCCGAC ATGCTCAATG TCACCTTGCA AGGGCCCACT CTTAACGGGA CCTTTGCCCA GAGCAAATGC CCCCAAGTGG AGTGGCTGGG CTGGCTCAAC ACCATCCAGC CCCCCTTCCT GTGGGTGCTG TTCGTGCTGG CCACCCTAGA GAACATCTTT

GTCCTCAGCG TCTTCTGCCT GCACAAGAGC AGCTGCACGG TGGCAGAGAT CTACCTGGGG AACCTGGCCG CAGCAGACCT GATCCTGGCC TGCGGGCTGC CCTTCTGGGC CATCACCATC TCCAACAACT TCGACTGGCT CTTTGGGGAG ACGCTCTGCC GCGTGGTGAA TGCCATTATC TCCATGAACC TGTACAGCAG CATCTGTTTC CTGATGCTGG TGAGCATCGA CCGCTACCTG GCCCTGGTGA AAACCATGTC CATGGGCCGG ATGCGCGGCG TGCGCTGGGC CAAGCTCTAC AGCTTGGTGA TCTGGGGGTG TACGCTGCTC CTGAGCTCAC CCATGCTGGT GTTCCGGACC ATGAAGGAGT ACAGCGATGA GGGCCACAAC GTCACCGCTT GTGTCATCAG CTACCCATCC CTCATCTGGG AAGTGTTCAC CAACATGCTC CTGAATGTCG TGGGCTTCCT GCTGCCCCTG AGTGTCATCA CCTTCTGCAC GATGCAGATC ATGCAGGTGC TGCGGAACAA CGAGATGCAG AAGTTCAAGG

AGATCCAGAC GGAGAGGAGG GCCACGGTGC TAGTCCTGGT TGTGCTGCTG CTATTCATCA TCTGCTGGCT GCCCTTCCAG ATCAGCACCT TCCTGGATAC GCTGCATCGC CTCGGCATCC TCTCCAGCTG CCAGGACGAG CGCATCATCG ATGTAATCAC ACAGATCGCC TCCTTCATGG CCTACAGCAA CAGCTGCCTC AACCCACTGG TGTACGTGAT CGTGGGCAAG CGCTTCCGAA AGAAGTCTTG GGAGGTGTAC CAGGGAGTGT GCCAGAAAGG GGGCTGCAGG TCAGAACCCA TTCAGATGGA GAACTCCATG GGCACACTGC GGACCTCCAT CTCCGTGGAA CGCCAGATTC ACAAACTGCA GGACTGGGCA GGGAGCAGAC AGTGAGCAAA CGCCAGCAGG GCTGCTGTGA ATTTGTGTAA GGATTGAGGG ACAGTTGCTT TTCAGCATGG GCCCAGGAAT GCCAAGGAGA CATCTATGCA CGACCTTGGG AAATGAGTTG ATGTCTCCGG TAAAACACCG

GAGACTAATT CCTGCCCTGC CCAATTTTGC AGGGAGCATG GCTGTGAGGA TGGGGTGAAC TCACGCACAG CCAAGGACTC CAAAATCACA ACAGCATTAC TGTTCTTATT TGCTGCCACA CCTGAGCCAG CCTGCTCCTT CCCAGGAGTG GAGGAGGCCT GGGGGCAGGG AGAGGAGTGA CTGAGCTTCC CTCCCGTGTG TTCTCCGTCC CTGCCCCAGC AAGACAACTT AGATCTCCAG GAGAACTGCC ATCCAGCTTT GGTGCAATGG CTGAGTGCAC AAGTGAGTTG TTGCCCTGGG TTTCTTTAAT CTATTCAGCT AGAACTTTGA AGGACAATTT CTTGCATTAA TAAAGGTTAA GCCCTGAGGG GTCCCTGATA ACAACCTGGA GACCAGGATT TTATGGCTCC CCTCACTGAT GGACAAGGAG GTCTGTGCCA AAGAAGAATC CAATAAGCAC ATATTGAGCA CTTGCTGTAT ATGCAGTATT GAGCACTGTA GGCAAGAGGG AAGAAAGAGA AGGAGCCATC TCCATCTTGA AGGAACTCAA

AGACTCAAGT GGGAACGACT GGGCACTGCC ACCACCAGAA AGCTGTTCGA TGAGACGGTC GAGCAGGGTG CTGTGGGTGA TATGGACAGC AGAAGGGGGA GCCAGGTTCC AGCTCACCAA TACTATTGCA CACCACCTGT CCTGCCTC -3' (FRAQ NO J (SEQ ED NO 2441)

5'-CAGATTCACA AACTGCAGGA CTGGGCAGGG AGCAGACAGT GAGCAAACGC CAGCAGGGCT GCTGTGAATT TGTGTAAGGA TTGAGGGACA GTTGCTTTTC AGCATGGGCC CAGGAATGCC AAGGAGACAT CTATGCACGA CCTTGGGAAA TGAGTTGATG TCTCCGGTAA AACACCGGAG ACTAATTCCT GCCCTGCCCA ATTTTGCAGG GAGCATGGCT GTGAGGATGG GGTGAACTCA CGCACAGCCA AGGACTCCAA AATCACAACA GCATTACTGT TCTTATTTGC TGCCACACCT GAGCCAGCCT GCTCCTTCCC

AGGAGTGGAG GAGGCCTGGG GGGAGGGAGA GGAGTGACTG AGCTTCCCTC CCGTGTGTTC TCCGTCCCTG CCCCAGCAAG ACAACTTAGA TCTCCAGGAG AACTGCCATC CAGCTTTGGT GCAATGGCTG AGTGCACAAG TGAGTTGTTG CCCTGGGTTT CTTTAATCTA TTCAGCTAGA ACTTTGAAGG ACAATTTCTT GCATTAATAA AGGTTAAGCC CTGAGGGGTC CCTGATAACA ACCTGGAGAC CAGGATTTTA TGGCTCCCCT CACTGATGGA CAAGGAGGTC TGTGCCAAAG AAGAATCCAA TAAGCACATA TTGAGCACTT GCTGTATATG CAGTATTGAG CACTGTAGGC AAGACCCAAG AAAGAGAAGG AGCCATCTCC ATCTTGAAGG AACTCAAAGA CTCAAGTGGG AACGACTGGG CACTGCCACC ACCAGAAAGC TGTTCGACGA GACGGTCGAG CAGGGTGCTG TGGGTGATAT GGACAGCAGA AGGGGGAGAC CAAGGTTCCA GCTCAACCAA TAACTATTGC

ACAACCACCT GTCCCTGCCT CAGTTCCCTT TTATGTAACA TGAAGTCGTT GTGAGGGTTA AAGGCAGTAA CAGGTATAAA GTACTTAGAA AAGCAAAGGG TGCTACGTAC ATGTGAGGCA TCATTACGCA GACGTAACTG GGATATGTTT ACTATAAGGA AAAGACACTG AGGTCTAGAA ATAGCTCCGT GGAGCAGAAT CAGTATTGGG AGCCGGTGGC GGTGTGAAGC ACCAGTGTCT GGCACACAGT AGGTGCTCAT TGGCTCCCTT CCACCTGTCA TTCCCACCAC CCTGAGGCCC CAACCGCCAC ACACACAGGA GCATTTGGAG AGAAGGCCAT GTCTTCAAAG TCTGATTTGT GATGAGGCAG AGGAAGATAT TTCTAATCGG TCTTGCCCAG AGGATCACAG TGCTGAGACC CCCCACCACC AGCCGGTACC TGGGAAGGGG GAGAGTGCAG GCCTGCTCAG GGACTGTTCC TGTCTCAGCA ACCAAGGGAT TGTTCCTGTC AATCAATGGT TTATTGGAAG GTGGCCCAGT ATGAGCCCTA

GAAGAGTGTG AAAAGGAATG GCAATGGTGT TCACCATCGG CAGTGCCAGG GCAGCACTCA TTCACTTGAT AAATGAATAT TTATTAGCTG GTTGGAGAGC TAGAACCTGG AGAGCTAGAA CCTGGAGAAC TAGAACCTGG AGGGCTAGAA CCTGGAGAGG CTAGAACCAA GAAGGGCTAG AACCTGGAGG GGCTAGAACC TAGAGAAGCT AAAACCTGAG CTAGAAGCTG GAGGACTAGA ACCTGGAGGG CTGGAATCTG AAGGGCTAGA ACCTGGAGGG CTGGAATCTG GAGAGCTAGA ACCTGGAGGG CTAGAACCTG GAGGGCTAGA ACCTAGAAGG GCTAGAACCT GGAGGGCTGG AATCTGGAGA GCTAGAACCT GGAGGGCTAG AACCTGGAGG GCTAGAACCT AGAAGGGCTA GAACCTGGAG GGCTAGAACC TGGCAGGTTA GAACCTAGAA GGGCTAGAAC CTGGAGAGCC AGAACCTGGA GGGCTAGAAC CTGGAAGGGC

TAGAACCTGT AGAGCTAGAA CATGGAGAGC TAGAACCCGG CAGGCTAGAA CCTGGCAAGC TAGAACCTGG AGGGAATGAA CCTGGAGGGC TAGAACCTGG AGAATGAGAA AAATTTACAT GGCAAAGAGC CCATAAATCC TGACCAATCC AACTCTGAAT TTTAAAGCAA AAGCGTGAAA AAAAAGATTC CCTCCTTACC CCCAACCCAC TCTTTTTTCC CACCACCCAC TCTCCTCTGC CTCAGTAAGT ATCTGGAGGA AGAAAACAGG TGAAAGAAGA AGTAAAAACC ATTTAGTATT AGTATTAGAA TGAAGTCAAA CTGTGCCACA CATGGTGAAT GAAAAAAAAA AAAAAGAGGC TGTGTTTTGT CACACAGGGC AGTCATTCAG CACCAGAGCA CGTGATGGTC TGAGACTCTC TTAGGAGCAG AGCTCTGCCG CAATGGCCAT GTGGGGATCC ACACCTGGTC TGAGGGGCAA CTGAGTCTGC GGGAGAAGAG CGGCCCTATG CATGGTGTAG ATGCCCTGAT AAAGAACATC

TGTCCTGTGA AAGACTCAAT GAGCTGTTAT GTTGTAAACA GGAAGCATTT CACATCCAAA CGAGAAAATC ATGTAAACAT GTGTCTTTTC TGTAGAGCAT AATAAATGGA TGAGGTTTTT GCAAAAAAAA AAAAAAAAA -3' (FRAQ NO (SEQ DD NO 2431) 5'-GGTGBCBTTGBGCBTGTCGGCGC-3' (FRAG NO 2276) (SEQ ID NO 11658) 5'-GGTCCCGTTBBGBGTGGGCCC-3' (FRAG NO 2277) (SEQ ID NO 11659) 5'-GCCAGCCCAGCCACTCCACTTGGGGGC-3' (FRAG NO 2278) (SEQ ID NO 11660)

5'-GGGTGGCCAGCACGAACAGCACCCAGAGGAAGGGGGGC-3' (FRAG NO 2279) (SEQ ID NO 11661) 5'-GGCCCAGAAGGGCAGCCCGCAGGCCAGGATCAGGTCTGCTGCGGCC-3'(FRAG NO 2280)(SEQ ID NO 11662) 5'-GGAGATAATGGCATTCACCACGCGGC-3' (FRAG NO 2281) (SEQ ID NO 11663) 5'-GGCCCAGCGCACGCCGCGCATCCGGCCC-3' (FRAG NO 2282) (SEQ ID NO 11664) 5'-GGGTTCTGACCTGCAGCCCCC-3' (FRAG NO 2283) (SEQ DD NO 11665)

5'-GTCTCCTTGGCATTCCTGGGCCC-3' (FRAG NO 2284) (SEQ ED NO 11666) 5'-CAGTCACTCCTCTCCCTGCCCCC-3' (FRAG NO 2285) (SEQ ID NO 11667) 5'-CTTGCTGGGGCAGGGACGG-3' (FRAG NO 2286) (SEQ DD NO 11668) 5'-GGTGBCBTTGBGCBTGTCGGCGC-3' (FRAG NO 2287) (SEQ ID NO 11669) 5'-GGTCCCGTTBBGBGTGGGCCC-3' (FRAG NO 2288) (SEQ ID NO 11670)

5'-GCCAGCCCAGCCACTCCACTTGGGGGC-3' (FRAG NO 2289) (SEQ IDNO 11671) 5'-GGGTGGCCAGCACGAACAGCACCCAGAGGAAGGGGGGC-3' (FRAG NO 2290) (SEQ ED NO 11672) 5'-GGCCCAGAAGGGCAGCCCGCAGGCCAGGATCAGGTCTGCTGCGGCC-3'(FRAG NO 2291)(SEQ DD NO 11673) 5'-GGAGATAATGGCATTCACCACGCGGC-3' (FRAG NO 2292) (SEQ DD NO 11674) 5'-GGCCCAGCGCACGCCGCGCATCCGGCCC-3' (FRAG NO 2293) (SEQ DD NO 11675) 5' GGGTTCTGACCTGCAGCCCCC-3' (FRAG NO 2294) (SEQ ID NO 11676) 5'-GTCTCCTTGGCATTCCTGGGCCC-3' (FRAG NO 2295) (SEQ DD NO 11677) 5' CAGTCACTCCTCTCCCTGCCCCC-3' (FRAG NO 2296) (SEQ ID NO 11678) 5'-CTTGCTGGGGCAGGGACGG-3' (FRAG NO 2297) (SEQ ED NO 11679)

5'-CCGTGTTGTCBGTGGTGCTG-3' (FRAG NO 2298) (SEQ DD O 11680) 5'-CCCGTTTGBGGTBTGGC-3' (FRAG NO 2299) (SEQ DD NO 11681) 5'-GCTCCBCCBBTTCCCTTTTCTCC-3' (FRAG NO 2300) (SEQ ID NO 11682) 5'-TTGTTTTCCGTTTCTCTTG-3' (FRAG NO 2301) (SEQ DD NO 11683) 5' CCGTCTGTGGTT-3' (FRAG NO 2302) (SEQ DD NO 11684)

B2 Adrenergic Receptor Kinase Nucleic Acids and Antisense Oligonucleotide Fragments

5'- GCCGCCGCCG CCAAGATGGC GGACCTGGAG GCGGTGCTGG CCGACGTGAG CTACCTGATG GCCATGGAGA AGAGCAAGGC CACGCCGGCC GCGCGCGCCA GCAAGAAGAT ACTGCTGCCC GAGCCCAGCA TCCGCAGTGT CATGCAGAAG TACCTGGAGG ACCGGGGCGA GGTGACCTTT GAGAAGATCT TTTCCCAGAA GCTGGGGTAC CTGCTCTTCC GAGACTTCTG CCTGAACCAC CTGGAGGAGG CCAGGCCCTT GGTGGAATTC TATGAGGAGA TCAAGAAGTA CGAGAAGCTG GAGACGGAGG AGGAGCGTGT GGCCCGCAGC CGGGAGATCT TCGACTCATA CATCATGAAG GAGCTGCTGG CCTGCTCGCA TCCCTTCTCG AAGAGTGCCA CTGAGCATGT CCAAGGCCAC

GTGGGGAAGA AGCAGGTGCC TCCGGATCTC TTCCAGCCAT ACATCGAAGA GATTTGTCAA AACCTCCGAG GGGACGTGTT CCAGAAATTC ATTGAGAGCG ATAAGTTCAC ACGGTTTTGC CAGTGGAAGA ATGTGGAGCT CAACATCCAC CTGACCATGA ATGACTTCAG CGTGCATCGC ATCATTGGGC GCGGGGGCTT TGGCGAGGTC TATGGGTGCC GGAAGGCTGA CACAGGCAAG ATGTACGCCA TGAAGTGCCT GGACAAAAAG CGCATCAAGA TGAAGCAGGG GGAGACCCTG GCCCTGAACG AGCGCATCAT GCTCTCGCTC GTCAGCACTG GGGACTGCCC ATTCATTGTC TGCATGTCAT ACGCGTTCCA CACGCCAGAC AAGCTCAGCT TCATCCTGGA CCTCATGAAC GGTGGGGACC TGCACTACCA CCTCTCCCAG CACGGGGTCT TCTCAGAGGC TGACATGCGC TTCTATGCGG CCGAGATCAT CCTGGGCCTG GAGCACATGC ACAACCGCTT CGTGGTCTAC

CGGGACCTGA AGCCAGCCAA CATCCTTCTG GACGAGCATG GCCACGTGCG GATCTCGGAC CTGGGCCTGG CCTGTGACTT CTCCAAGAAG AAGCCCCATG CCAGCGTGGG CACCCACGGG TACATGGCTC CGGAGGTCCT GCAGAAGGGC GTGGCCTACG ACAGCAGTGC CGACTGGTTC TCTCTGGGGT GCATGCTCTT CAAGTTGCTG CGGGGGCACA GCCCCTTCCG GCAGCACAAG ACCAAAGACA AGCATGAGAT CGACCGCATG ACGCTGACGA TGGCCGTGGA GCTGCCCGAC TCCTTCTCCC CTGAACTACG CTCCCTGCTG GAGGGGTTGC TGCAGAGGGA TGTCAACCGG AGATTGGGCT GCCTGGGCCG AGGGGCTGAG GAGGTGAAAG AGAGCCCCTT TTTCCGCTCC CTGGACTGGC AGATGGTCTT CTTGCAGAAG TACCCTCCCC CGCTGATCCC CCCACGAGGG GAGGTGAACG CGGCCGACGC CTTCGACATT GGCTCCTTCG ATGAGGAGGA CACAAAAGGA ATCAAGTTAC

TGGACAGTGA TCAGGAGCTC TACCGCAACT TCCCCCTCAC CATCTCGGAG CGGTGGCAGC AGGAGGTGGC AGAGACTGTC TTCGACACCA TCAACGCTGA GACAGACCGG CTGGAGGCTC GCAAGAAAGC CAAGAACAAG CAGCTGGGCC ATGAGGAAGA CTACGCCCTG GGCAAGGACT GCATCATGCA TGGCTACATG TCCAAGATGG GCAACCCCTT CCTGACCCAG TGGCAGCGGC GGTACTTCTA CCTGTTCCCC AACCGCCTCG AGTGGCGGGG CGAGGGCGAG GCCCCGCAGA GCCTGCTGAC CATGGAGGAG ATCCAGTCGG TGGAGGAGAC GCAGATCAAG GAGCGCAAGT GCCTGCTCCT CAAGATCCGC GGTGGGAAAC AGTTCATTTT GCAGTGCGAT AGCGACCCTG AGCTGGTGCA GTGGAAGAAG GAGCTGCGCG ACGCCTACCG CGAGGCCCAG CAGCTGGTGC AGCGGGTGCC CAAGATGAAG AACAAGCCGC GCTCGCCCGT GGTGGAGCTG

AGCAAGGTGC CGCTGGTCCA GCGCGGCAGT GCCAACGGCC TCTGACCCGC CCACCCGCCT CCAGGAAGCT ACCTGGAGGA GGTGAGTCTT AGCGGATGAG

TAGGAGTTGT CCACGGAGGA AGGTACACAG AAGGGCTTCC AGGCCCAGGA AACAGCAGAG GCACAGAAGT GAGAATGGGT GGGTGAGTTG GTGGGGAAAC TCCAGGTGCA GAGGATGGTA GCGAAACAAA CTGGAGCATT AAGGTCCAAG TCCTCCAAGA TCTTGACTTG CAGATTAAGG AGTTTGTTCA CCTAATCTGC TTTGGGCAGA GTGTGGTGAG TCCTAGAGAC CCCTCTAGGT CTCTCCTCTC AGTAGCCCCA GAAGGCCTGG AGAGCTGCTT CTGGGTGCCA AGCAGGCAGT GACTCCATCA GATCTAGATT TGGGAAAAGC ATCCCTGGTC AGGGCCTGCA TCAGGGCAGT GGCTGGCCAT GAGGACCCTG AGAAGTAGAC AGATTCACGG AGATTCTCAG GAGGCCAGAC

AGGAGACTAT GGTGACAAAT TAGATTAGAG AAGGGGAGAG AATGAAGGAG CAGTTGGGGT AAAAGAAAAC TGAGGCTGAC ATGGGTATAT GGGTGGCGAG TGACTCACCA CCCACTGAGA GGAGAACCTC ACAAGCTCTG ACATGCTCTG GTTCCAGGTT CTGTTGGGGC TGATCCAAGA TGGTAGCCTA GAGGTGCACA GAGATGGGGG CCTTGCTTTG CAAAAGGATG CTGGCTGCTG GCCCACAGCA TGGTAATGAG ATTTGAGCTT TATGTGCCCA GGGCTGGGAG GAGGGTCCTG TCACTTTGAA AGCAAAGAGA GGCTCTAGAG AGGGGCATGT TGAGATAGGA ATGCTGCCTT GAGACACCTG GCTTTCCCCA CTCTGGGTGG CTCTCAGCAG GGTGGGTTTC CCCTGCCAGG CAGCACTGAA CCTCTGTGCG CTTCCGGCTG GGAGAGTTTT TACCGTAACT ACATGTGGAA CCATCCTGAA GGAACATCTG GATGGGATGG GGTACAGGGA AGGGAGCTGC CAAGAGTGCT

OGCCAOGGAC CTGGGTCTAT GAGCTGGTTG GGGGGTGGOG TTGGGTGCAG GGTACTTGAT CCTGAGTGGG CCTTCTGCGG CCAGGATTGG TTCTAGAGTA GGAGGGGTGG GATCGGGGAT GGGGGAAGCC TGTAACTGCG CTGCAGTTGT CAGGTCCCAG GTTCTGGGTG ACCTACTAAG GATTCTGGGT CCAGTGTGGG TCCCAGGTTA GACGTCCTAG TCCTGAGTCC GTGTCCACAG TTCTGGGTGT TGAGTCTAGG ACAGTGATCT GGAGTTGACA GTCCAATCTA GGTCTGAGTC CTGACCCCAA GTCTAGAGTT CAGGGTCATG GTAGTAGCCT AGGGTCAGAA TCAAGGTTGG GGTCAGTAAC CAGGATGGGA TCGAGGTCAT GGTCCAAAAT CTGGATCTGG GGACCTGTTG GGGGTCTGAG GTGAGTGTCG CAGTCTGGGT ATGGCGTTGG AGACCCAGGG CTGTGATCTG AGGTCATGGT TAGAGTCTCA GGTGGTGGGC CAAGGTTTGA GTCTGGGGTC

CTGTTTGGAG TCTGGTGTCA GGTCGTGGAC TGCGTCCAAG GTCAGGGAGT CCGGGGTTAT AGCCAGGGTC TGAGATGAAA GTCCCAGATG GTGTTCAGAG GTCTGAATCT GTGTCTTGGT GAGCGTCCAG GTTCCCTGTG ATCACGTTTG GTGTCAGGGC TGCGGCCCGA CTGGGGAGCC TGGGATCCAG AGATGTGACC CGAGGTTGTG GTCAGAGAAT GGGTCTCGGG TCGTCTTCGT GCCGGGTCCC TGTCGTGTTC CAGGCCCGGG TCTCCGTCCA GCATCGAGGG CCGAGGTCAC GGCCAGGGTC TGAGCCCGCG GTCGCAGGTC TGGTTCGGGG TCAGATTCCG CGCGGCCTCC AGGGGGCGCC GTCGCCGCCC GGCTCGGCCC CTCGCGGGCT CGCTGGCGTT GTGCGCGGCA GGCGGGGCCG GAGGCGGCGG CGGCTCCGGG GGCGCGGGCC GGGCGGCGGC GGCGGCGGCG CCCCGACTGC AGTCCCGGCG GGAGCGGAGC GCGAAGCGCG GGGCCGGGCC

CGGAGCCGGC GCCATGGGGC GGCGCCGCCT GTGAGCGGCG GCGAGCGGAG CCGCGGGCGC CGAGCAGGGC CAGGCGGGAG CGTCGGCGCC CGAGGCCGAG CGAGCCGCGG CCGGGCCGGG CCGAGCGCCG AGCGAGCAGG AGCGGCGGCG GCGGCGGCGG CGGCGGGAGG AGGCAGCGCC GCCGCCAAGA TGGCGGACCT GGAGGCGGTG CTGGCCGACG TGAGCTACCT GATGGCCATG GAGAAGAGCA AGGCCACGCC GGCCGCGCGC GCCAGCAAGA AGATACTGCT GCCCGAGCCC AGGTGAGGAG AAGCT-3' (FRAG NO J (SEQ ID NO 11799) 5'-CCAGGAAGCT ACCTGGAGGA GGTGAGTCTT AGCGGATGAG TAGGAGTTGT CCACGGAGGA AGGTACACAG AAGGGCTTCC AGGCCCAGGA AACAGCAGAG

GCACAGAAGT GAGAATGGGT GGGTGAGTTG GTGGGGAAAC TCCAGGTGCA GAGGATGGTA GCGAAACAAA CTGGAGCATT AAGGTCCAAG TCCTCCAAGA TCTTGACTTG CAGATTAAGG AGTTTGTTCA CCTAATCTGC TTTGGGCAGA GTGTGGTGAG TCCTAGAGAC CCCTCTAGGT CTCTCCTCTC AGTAGCCCCA GAAGGCCTGG AGAGCTGCTT CTGGGTGCCA AGCAGGCAGT GACTCCATCA GATCTAGATT TGGGAAAAGC ATCCCTGGTC AGGGCCTGCA TCAGGGCAGT GGCTGGCCAT GAGGACCCTG AGAAGTAGAC AGATTCACGG AGATTCTCAG GAGGCCAGAC AGGAGACTAT GGTGACAAAT TAGATTAGAG AAGGGGAGAG AATGAAGGAG CAGTTGGGGT AAAAGAAAAC TGAGGCTGAC ATGGGTATAT GGGTGGCGAG TGACTCACCA CCCACTGAGA GGAGAACCTC ACAAGCTCTG ACATGCTCTG GTTCCAGGTT CTGTTGGGGC

TGATCCAAGA TGGTAGCCTA GAGGTGCACA GAGATGGGGG CCTTGCTTTG CAAAAGGATG CTGGCTGCTG GCCCACAGCA TGGTAATGAG ATTTGAGCTT TATGTGCCCA GGGCTGGGAG GAGGGTCCTG TCACTTTGAA AGCAAAGAGA GGCTCTAGAG AGGGGCATGT TGAGATAGGA ATGCTGCCTT GAGACACCTG GCTTTCCCCA CTCTGGGTGG CTCTCAGCAG GGTGGGTTTC CCCTGCCAGG CAGCACTGAA CCTCTGTGCG CTTCCGGCTG GGAGAGTTTT TACCGTAACT ACATGTGGAA CCATCCTGAA GGAACATCTG GATGGGATGG GGTACAGGGA AGGGAGCTGC CAAGAGTGCT GGCCAGGGAC CTGGGTCTAT GAGCTGGTTG GGGGGTGGGG TTGGGTGCAG GGTACTTGAT CCTGAGTGGG CCTTCTGCGG CCAGGATTGG TTCTAGAGTA GGAGGGGTGG GATCGGGGAT GGGGGAAGCC TGTAACTGCG CTGCAGTTGT CAGGTCCCAG GTTCTGGGTG

ACCTACTAAG GATTCTGGGT CCAGTGTGGG TCCCAGGTTA GACGTCCTAG TCCTGAGTCC GTGTCCACAG TTCTGGGTGT TGAGTCTAGG ACAGTGATCT GGAGTTGACA GTCCAATCTA GGTCTGAGTC CTGACCCCAA GTCTAGAGTT CAGGGTCATG GTAGTAGCCT AGGGTCAGAA TCAAGGTTGG GGTCAGTAAC CAGGATGGGA TCGAGGTCAT GGTCCAAAAT CTGGATCTGG GGACCTGTTG GGGGTCTGAG GTGAGTGTCG CAGTCTGGGT ATGGCGTTGG AGACCCAGGG CTGTGATCTG AGGTCATGGT TAGAGTCTCA GGTGGTGGGC CAAGGTTTGA GTCTGGGGTC CTGTTTGGAG TCTGGTGTCA GGTCGTGGAC TGCGTCCAAG GTCAGGGAGT CCGGGGTTAT AGCCAGGGTC TGAGATGAAA GTCCCAGATG GTGTTCAGAG GTCTGAATCT GTGTCTTGGT GAGCGTCCAG GTTCCCTGTG ATCACGTTTG GTGTCAGGGC TGCGGCCCGA CTGGGGAGCC TGGGATCCAG

AGATGTGACC CGAGGTTGTG GTCAGAGAAT GGGTCTCGGG TCGTCTTCGT GCCGGGTCCC TGTCGTGTTC CAGGCCCGGG TCTCCGTCCA GCATCGAGGG CCGAGGTCAC GGCCAGGGTC TGAGCCCGCG GTCGCAGGTC TGGTTCGGGG TCAGATTCCG CGCGGCCTCC AGGGGGCGCC GTCGCCGCCC GGCTCGGCCC CTCGCGGGCT CGCTGGCGTT GTGCGCGGCA GGCGGGGCCG GAGGCGGCGG CGGCTCCGGG GGCGCGGGCC GGGCGGCGGC GGCGGCGGCG CCCCGACTGC AGTCCCGGCG GGAGCGGAGC GCGAAGCGCG GGGCCGGGCC CGGAGCCGGC GCCATGGGGC GGCGCCGCCT GTGAGCGGCG GCGAGCGGAG CCGCGGGCGC CGAGCAGGGC CAGGCGGGAG CGTCGGCGCC CGAGGCCGAG CGAGCCGCGG CCGGGCCGGG CCGAGCGCCG AGCGAGCAGG AGCGGCGGCG GCGGCGGCGG CGGCGGGAGG AGGCAGCGCC

GCCGCCAAGA TGGCGGACCT GGAGGCGGTG CTGGCCGACG TGAGCTACCT GATGGCCATG GAGAAGAGCA AGGCCACGCC GGCCGCGCGC GCCAGCAAGA AGATACTGCT GCCCGAGCCC AGGTGAGGAG AAGCT-3' (FRAG NO J (SEQ ID NO 11798)

5'-GCCGCCGCCG CCAAGATGGC GGACCTGGAG GCGGTGCTGG CCGACGTGAG CTACCTGATG GCCATGGAGA AGAGCAAGGC CACGCCGGCC GCGCGCGCCA GCAAGAAGAT ACTGCTGCCC GAGCCCAGCA TCCGCAGTGT CATGCAGAAG TACCTGGAGG ACCGGGGCGA GGTGACCTTT GAGAAGATCT TTTCCCAGAA GCTGGGGTAC CTGCTCTTCC GAGACTTCTG CCTGAACCAC CTGGAGGAGG CCAGGCCCTT GGTGGAATTC TATGAGGAGA TCAAGAAGTA CGAGAAGCTG GAGACGGAGG

AGGAGCGTGT GGCCCGCAGC CGGGAGATCT TCGACTCATA CATCATGAAG GAGCTGCTGG CCTGCTCGCA TCCCTTCTCG AAGAGTGCCA CTGAGCATGT CCAAGGCCAC CTGGGGAAGA AGCAGGTGCC TCCGGATCTC TTCCAGCCAT ACATCGAAGA GATTTGTCAA AACCTCCGAG GGGACGTGTT CCAGAAATTC ATTGAGAGCG ATAAGTTCAC ACGGTTTTGC CAGTGGAAGA ATGTGGAGCT CAACATCCAC CTGACCATGA ATGACTTCAG CGTGCATCGC ATCATTGGGC GCGGGGGCTT TGGCGAGGTC TATGGGTGCC GGAAGGCTGA CACAGGCAAG ATGTACGCCA TGAAGTGCCT GGACAAAAAG CGCATCAAGA TGAAGCAGGG GGAGACCCTG GCCCTGAACG AGCGCATCAT GCTCTCGCTC GTCAGCACTG GGGACTGCCC ATTCATTGTC TGCATGTCAT ACGCGTTCCA CACGCCAGAC AAGCTCAGCT TCATCCTGGA CCTCATGAAC GGTGGGGACC

TGCACTACCA CCTCTCCCAG CACGGGGTCT TCTCAGAGGC TGACATGCGC TTCTATGCGG CCGAGATCAT CCTGGGCCTG GAGCACATGC ACAACCGCTT CGTGGTCTAC CGGGACCTGA AGCCAGCCAA CATCCTTCTG GACGAGCATG GCCACGTGCG GATCTCGGAC CTGGGCCTGG CCTGTGACTT CTCCAAGAAG AAGCCCCATG CCAGCGTGGG CACCCACGGG TACATGGCTC CGGAGGTCCT GCAGAAGGGC GTGGCCTACG ACAGCAGTGC CGACTGGTTC TCTCTGGGGT GCATGCTCTT CAAGTTGCTG CGGGGGCACA GCCCCTTCCG GCAGCACAAG ACCAAAGACA AGCATGAGAT CGACCGCATG ACGCTGACGA TGGCCGTGGA GCTGCCCGAC TCCTTCTCCC CTGAACTACG CTCCCTGCTG GAGGGGTTGC TGCAGAGGGA TGTCAACCGG AGATTGGGCT GCCTGGGCCG AGGGOCTCAG GAGGTGAAAG AGAGCCCCTT TTTCCGCTCC CTGGACTGGC AGATGGTCTT

CTTGCAGAAG TACCCTCCCC CGCTGATCCC CCCACGAGGG GAGGTGAACG CGGCCGACGC CTTCGACATT GGCTCCTTCG ATGAGGAGGA CACAAAAGGA ATCAAGTTAC TGGACAGTGA TCAGGAGCTC TACCGCAACT TCCCCCTCAC CATCTCGGAG CGGTGGCAGC AGGAGGTGGC AGAGACTGTC TTCGACACCA TCAACGCTGA GACAGACCGG CTGGAGGCTC GCAAGAAAGC CAAGAACAAG CAGCTGGGCC ATGAGGAAGA CTACGCCCTG GGCAAGGACT GCATCATGCA TGGCTACATG TCCAAGATGG GCAACCCCTT CCTGACCCAG TGGCAGCGGC GGTACTTCTA CCTGTTCCCC AACCGCCTCG AGTGGCGGGG CGAGGGCGAG GCCCCGCAGA GCCTGCTGAC CATGGAGGAG ATCCAGTCGG TGGAGGAGAC GCAGATCAAG GAGCGCAAGT GCCTGCTCCT CAAGATCCGC GGTGGGAAAC AGTTCATTTT GCAGTGCGAT AGCGACCCTG AGCTGGTGCA

GTGGAAGAAG GAGCTGCGCG ACGCCTACCG CGAGGCCCAG CAGCTGGTGC AGCGGGTGCC CAAGATGAAG AACAAGCCGC GCTCGCCCGT GGTGGAGCTG AGCAAGGTGC CGCTGGTCCA GCGCGGCAGT GCCAACGGCC TCTGACCCGC CCACCCGCCT-3' (FRAG NO J (SEQ ID NO 11797)

CCR-2 CC Chemokine Receptor Nucleic Acids and Antisense Oligonucleotide Fragments 5'-CTTTGTGAAG AAGGAATTGG CAACACTGAA ACCTCCAGAA CAAAGGCTGT CACTAAGGTC CCGCTGCCTT GATGGATTAT ACACTTGACC TCAGTGTGAC AACAGTGACC GACTACTACT ACCCTGATAT CTTCTCAAGC CCCTGTGATG CGGAACTTAT TCAGACAAAT GGCAAGTTGC TCCTTGCTGT CTTTTATTGC CTCCTGTTTG TATTCAGTCT TCTGGGAAAC AGCCTGGTCA TCCTGGTCCT TGTGGTCTGC AAGAAGCTGA GGAGCATCAC AGATGTATAC CTCTTGAACC TGGCCCTGTC TGACCTGCTT TTTGTCTTCT CCTTCCCCTT TCAGACCTAC TATCTGCTGG ACCAGTGGGT GTTTGGGACT GTAATGTGCA AAGTGGTGTC TGGCTTTTAT TACATTGGCT TCTACAGCAG CATGTTTTTC ATCACCCTCA TGAGTGTGGA CAGGTACCTG GCTGTTGTCC ATGCCGTGTA TGCCCTAAAG GTGAGGACGA TCAGGATGGG CACAACGCTG TGCCTGGCAG

TATGGCTAAC CGCCATTATG GCTACCATCC CATTGCTAGT GTTTTACCAA GTGGCCTCTG AAGATGGTGT TCTACAGTGT TATTCATTTT ACAATCAACA GACTTTGAAG TGGAAGATCT TCACCAACTT CAAAATGAAC ATTTTAGGCT TGTTGATCCC ATTCACCATC TTTATGTTCT GCTACATTAA AATCCTGCAC CAGCTGAAGA GGTGTCAAAA CCACAACAAG ACCAAGGCCA TCAGGTTGGT GCTCATTGTG GTCATTGCAT CTTTACTTTT CTGGGTCCCA TTCAACGTGG TTCTTTTCCT CACTTCCTTG CACAGTATGC ACATCTTGGA TGGATGTAGC ATAAGCCAAC AGCTGACTTA TGCCACCCAT GTCACAGAAA TCATTTCCTT TACTCACTGC TGTGTGAACC CTGTTATCTA TGCTTTTGTT GGGGAGAAGT TCAAGAAACA CCTCTCAGAA ATATTTCAGA AAAGTTGCAG CCAAATCTTC AACTACCTAG GAAGACAAAT GCCTAGGGAG AGCTGTGAAA AGTCATCATC

CTGCCAGCAG CACTCCTCCC GTTCCTCCAG CGTAGACTAC ATTTTGTGAG GATCAATGAA GACTAAATAT AAAAAACATT TTCTTGAATG GCATGCTAGT AGCAGTGAGC AAAGGTGTGG GTGTGAAAGG TTTCCAAAAA AAGTTCAGCA TGAAGGATGC CGTGTGTGTT GTTGCCAACA CTTGGAACAC AATGACTGGA GACATAGTTG TGCATGCCTG GCACAACATC AAGCCTGTGA TTGTGTTTAT TGATGATGTT GAACAAGTGG TGGCTTTGAG GGATTCTGTA TGCCAAGTGG AAAAAAAAGA TGTCTCCGGA ATTCGACAGG TTATCA-3' (FRAG NO _) (SEQ ID NO 11831) CCR-4 CC Chemokine Receptor Nucleic Acids and Antisense Oligonucleotide Fragments

5*-TTTCATCTCT CCGGGCTTAT TTGCTGGTTT CTCCGAATGC GGGCCTTGTC TGGTTCACGC TGGATCCCCA ACGCCTAGAA CAGTGCGTGG CACGCAGTTC GTCCTTCTAT AAATATCGGA CTAAATGCAT CTCTGTGATG GTAATACCCA CACGGTGTTG TGAGAATGAA TGAGTGATTC TGTGCAAGTT CCTAGTGATC TGTTACAAAA AGTACTGGTC GCTAAATTAC TCTTATAATA AAGCATACTT TTAGGATAAT AAAGCACTAT TCGCGAATTG GTTACCGCTA TTATGAAATT ACTGAGCAAT ACATATCTAC ATCTGATCAG TCTCCAGAAT TATGCCAAAT CCTACCTTCT TCTGAAAGTA TCTCCTAATT ATCTGCACCT GACCCTAGTG ATGCTGTGAA TGTGCAAGTA TAGCTACATC CTCCGAAGGA AGGATCTTTA CTCCTTTTAC CTCCTGAATG GGCTGCGTCT GCTGAAAGCG CGGGGGAATG GGCGGTTGGA AGCTTGGCCC TACTTCCAGC ATTGCCGCCT ACTGGTTGGG

TTACTCCAGC AAGTCACTCC CCTTCCCTGG GCCTCAGTGT CTCTACTGTA GCATTCCCAG GTCTGGAATT CCATCCACTT TAGCAAGGAT GGACGCGCCA CAGAGAGACG CGTTCCTAGC CCGCGCTTCC CACCTGTCTT CAGGCGCATC CCGCTTCCCT CAAACTTAGG AAATGCCTCT GGGAGGTCCT GTCCGGCTCC GGACTCACTA CCGACCACCC GCAAACAGCA GGGTCCCCTG GGCTTCCCAA GCCGCGCACC TCTCCGCCCC GCCCCTGCGC CCTCCTTCCT CGCGTCTGCC CCTCTCCCCC ACCCCGCCTT CTCCCTCCCC GCCCCAGCGG CGCATGCGCC GCGCTCGGAG CGTGTTTTTA TAAAAGTCCG GCCGCGGCCA GAAACTTCAG TTTGTTGGCT GCGGCAGCAG GTAGCAAAGT GACGCCGAGG GCCTGAGTGC TCCAGTAGCC ACCGCATCTG GAGAACCAGC GGTTACCATG GAGGGGATCA GTGTAAGTCC AGTTTCAACC TGCTTTGTCA TAAATGTACA AACGTTTGAA

CTTAGAGCGC AGCCCCTCTC CGAGCGGGCA GAAGCGGCCA GGACATTGGA GGTACCCGTA CTCCAAAAAA GGGTCACCGA AAGGAGTTTT CTTGACCATG CCTATATAGT GCGGGTGGGT GGGGGGGGAG CAGGATTGGA ATCTTTTTCT CTGTGAGTCG AGGAGAAACG ACTGGAAAGA GCGTTCCAGT GGCTGCATGT GTCTCCCCCT TGAGTCCCGC CGCGCGCGGC GGCTTGCACG CTGTTTGCAA ACGTAAGAAC ATTCTGTGCA CAAGTGCAGA GAAGGCGTGC GCGCTGCCTC GGGACTCAGA CCACCGGTCT CTTCCTTGGG GAAGCGGGGA TGTCTTGGAG CGAGTTACAT TGTCTGAATT TAGAGGCGGA GGGCGGCGTG CCTGGGCTGA CTTCCCAGGA GGAGATTGCG CCCGCTTTAA CTTCGGGGTT AAGCGCCTGG TGACTGTTCT TGACACTGGG TGCGTGTTTG TTAAACTCTG TGCGGCCGAC GGAGCTGTGC CAGTCTCCCA GCACAGTAGG CAGAGGGCGG GAGAGGCGGG

TGGACCCACC GCGCCGATCC TCTGAGGGGA TCGAGTGGTG GCAGCAGCTA GGAGTTGATC CGCCCGCGCG CTTTGGGTTT GAGGGGGAAA CCTTCCCGCC GTCCGAAGCG CGCCTCTTCC CCACGGCCGC GAGTGGGTCC TGCAGTTCGA GAGTTTGGGG TCGTGCAGAG GTCAGCGGAG TGGTTTGACC TCCCCTTTGA CACCGCGCAG CTGCCAGCCC TGAGATTTGC GCTCCGGGGA TAGGAGCGGG TACGGGGTGA GGGGCGGGGG CGGTTAAGAC CGCACCTGGG CTGCCAGGTC GCCGCCGCGA AGACTGGCAG GTGCAAGTGG GGAAACCGTT TGGCTCTCTC CGAGTCCAGT TGTGATGTTT AACCGTCGGT GGTTTCCAGA AACCTTTTGA AACCCTCTTG CTAGGGAGTT TTTGGTTTCC TGCAGCGGCG CGCAATTCAA AGACGCTCGC GGCGGAGCCG CCCAGTCGCT CCCCAGCACC CTGTGGGACA GAGCCTGGCG TGTCGCCCAG CGGAGCCCCT GCAGCGCTGC

TTGCGGGCGG TTGGCGTGGG TGTAGTGGGC AGCCGCGGCG GCCCGGGGCT GGACGACCCG GCCCCCCGCG TGCCCACCGC CTGGAGGCTT CCAGCTGCCC ACCTCCGGCC GGGTTAACTG GATCAGTGGC GGGGTAATGG GAAGCCACCC GGGAGAGTGA GGAAATGAAA CTTGGGGCGA GGACCACGGG TGCAGACCCC GTTACCTTCT CCACCCAGGA AAATGCCCCG CTCCCTAACG TCCCAAACGC GCCAAGTGAT AAACACGAGG ATGGCAAGAG ACCCACACAC CGGAGGAGCG CCCGCTTGGG GGAGGAGGTG CCGTTTGTTC ATTTTCTGAC ACTCCCGCCC AATATACCCC AAGCACCGAA GGGCCTTCGT TTTAAGACCG CATTCTCTTT ACCCACTACA AGTTGCTTGA AGCCCAGAAT GGTTTGTATT TAGGCAGGCG TGGGAAAATT AAGTTTTTGC GCTTTAGGAG AATGAGTCTT TGCAACGCCC CCGCCCTCCC CCCGTGATCC TCCCTTCTCC

CCTCTTCCCT CCCTGGGCGA AAAACTTCTT ACAAAAAGTT AATCACTGCC CCTCCTAGCA GCACCCACCC CACCCCCCAC GCCGCCTGGG AGTGGCCTCT TTGTGTGTAT TTTTTTTTTC CTCCTAAGGA AGGTTTTTTT TCTTCCCTCT AGTGGGCGGG GCAGAGGAGT TAGCCAAGAT GTGACTTTGA AACCCTCAGC GTCTCAGTGC CCTTTTGTTC TAAACAAAGA ATTTTGTAAT TGGTTCTACC AAAGAAGGAT ATAATGAAGT CACTATGGGA AAAGATGGGG AGGAGAGTTG TAGGATTCTA CATTAATTCT CTTGTGCCCT TAGCCCACTA CTTCAGAATT TCCTGAAGAA AGCAAGCCTG AATTGGTTTT TTAAATTGCT TTAAAAATTT TTTTTAACTG GGTTAATGCT TGCTGAATTG GAAGTGAATG TCCATTCCTT TGCCTCTTTT GCAGATATAC ACTTCAGATA ACTACACCGA GGAAATGGGC TCAGGGGACT ATGACTCCAT GAAGGAACCC TGTTTCCGTG AAGAAAATGC

TAATTTCAAT AAAATCTTCC TGCCCACCAT CTACTCCATC ATCTTCTTAA CTGGCATTGT GGGCAATGGA TTGGTCATCC TGGTCATGGG TTACCAGAAG AAACTGAGAA GCATGACGGA CAAGTACAGG CTGCACCTGT CAGTGGCCGA CCTCCTCTTT GTCATCACGC TTCCCTTCTG GGCAGTTGAT GCCGTGGCAA ACTGGTACTT TGGGAACTTC CTATGCAAGG CAGTCCATGT CATCTACACA GTCAACCTCT ACAGCAGTGT CCTCATCCTG GCCTTCATCA GTCTGGACCG CTACCTGGCC ATCGTCCACG CCACCAACAG TCAGAGGCCA AGGAAGCTGT TGGCTGAAAA GGTGGTCTAT GTTGGCGTCT GGATCCCTGC CCTCCTGCTG ACTATTCCCG ACTTCATCTT TGCCAACGTC AGTGAGGCAG ATGACAGATA TATCTGTGAC CGCTTCTACC CCAATGACTT GTGGGTGGTT GTGTTCCAGT TTCAGCACAT CATGGTTGGC CTTATCCTGC CTGGTATTGT CATCCTGTCC

TGCTATTGCA TTATCATCTC CAAGCTGTCA CACTCCAAGG GCCACCAGAA GCGCAAGGCC CTCAAGACCA CAGTCATCCT CATCCTGGCT TTCTTCGCCT GTTGGCTGCC TTACTACATT GGGATCAGCA TCGACTCCTT CATCCTCCTG GAAATCATCA AGCAAGGGTG TGAGTTTGAG AACACTGTGC ACAAGTGGAT TTCCATCACC GAGGCCCTAG CTTTCTTCCA CTGTTGTCTG AACCCCATCC TCTATGCTTT CCTTGGAGCC AAATTTAAAA CCTCTGCCCA GCACGCACTC ACCTCTGTGA GCAGAGGGTC CAGCCTCAAG ATCCTCTCCA AAGGAAAGCG AGGTGGACAT TCATCTGTTT CCACTGAGTC TGAGTCTTCA AGTTTTCACT CCAGCTAACA CAGATGTAAA AGACTTTTTT TTATACGATA AATAACTTTT TTTTAAGTTA CACATTTTTC AGATATAAAA GACTGACCAA TATTGTACAG TTTTTATTGC TTGTTGGATT TTTGTCTTGT GTTTCTTTAG TTTTTGTGAA

GTTTAATTGA CTTATTTATA TAAATTTTTT TTGTTTCATA TTGATGTGTG TCTAGGCAGG ACCTGTGGCC AAGTTCTTAG TTGCTGTATG TCTCGTGGTA GGACTGTAGA AAAGGGAACT GAACATTCCA GAGCGTGTAG TGAATCACGT AAAGCTAGAA ATGATCCCCA GCTGTTTATG CATAGATAAT CTCTCCATTC CCGTGGAACG TTTTTCCTGT TCTTAAGACG TGATTTTGCT GTAGAAGATG GCACTTATAA CCAAAGCCCA AAGTGGTATA GAAATGCTGG TTTTTCAGTT TTCAGGAGTG GGTTGATTTC AGCACCTACA GTGTACAGTC TTGTATTAAG TTGTTAATAA AAGTACATGT TAAACTTACT TAGTGTTATG TTCTGATTTC TGTTGACATT CTTTTGGCTA GTAGAAGACA AAAGTAATAC ATTTATGGTA TGCAAAGCAC TATCCTAGGT ATTTCATTGT AATATTTTAC TTACCCCTTA TCACAACTCT GATAGATTCT GCTTCTGTTA CTAATTACAT TTTATAGAAG

AGGAAACGGA GGCACAGAAA GCCTAAGTAA CTTGGTTAAA GGCATGTAGT AAGTATCAAA TCCTGTATTT TAAACCAGGT AACATGACTT AACGAATCTG AAGCCTTCAC CACTTTAAAT TCAAATGGAA GTTTAGAAAT GGCCAGCCAG CACCTATTTG TATGAAAGGT CATCTTTCAG AGGATAAGCA TGTATAAAGA AGAAAAGGTA TGGAGTCGTG TTTGGATTTT ACTCCACCAT C-3' (FRAG NO J (SEQ ID NO 11832)

CD-34 Nucleic Acids and Antisense Oligonucleotide Fragments 5'-AGGATGATGG TGATGGGGAA CTAAATGGGG AAATATGGAA GGTCACAGGA AAAGTTAACA CAAGTTAGCA AAAGTTAAC ATAACACAAA AAGGTCTTGC

AGGAAAAAAA AAAGAAAAGA AAAGAAAGAA AAAGTCTCCA AGAATGGTTT GGACAGCCAA AATGAATACT TATAGTCACG TATACCTGCT CACTCCTGAC GCTTCACTCA CACACAGCAC AGGATCTGGT GAGGCTATCA TAAATGTGC CACATTGTGG TTAAGTTTTA CCTGATTAAC GAAATGCTCA CACTTCTAAA CTGAGGTCCT TACAGTAGAT TCCTTTTGCA AGATTGTTAC TGGCTTACAA CTTAAAAATA AAGGAAAATC ACAAGGAAAG AAAAGTGGGG AAAAAATCGG AGGAAACTTG CCCCTGCCCT GGCCACCGGC AAGGCTGCCA CAAAGGGGTT AAAAGTTAAG TGGAAGTGGA GCTTGAAGAA GTGGGATGGG GCCTCTCCAG GAAAGCTGAA CGAGGCATCT GGAGCCCGAA CAAACCTCCA CCTTTTTTGG CCTCGACGGC GGCAACCCAG CCTCCCTCCT AACGCCCTCC GCCTTTGGGA CCAACCAGGG GAGCTCAAGT TAGTAGCAGC CAAGGAGAGG

CGCTGCCTTG CCAAGACTAA AAAGGGAGGG GAGAAGAGAG GAAAAAAGCA AGAATCCCCC ACCCCTCTCC CGGGCGGAGG GGGCGGGAAG AGCGCGTCCT GGCCAAGCCG AGTAGTGTCT TCCACTCGGT GCGTCTCTCT AGGAGCCGCG CGGGAAGGAT GCTGGTCCGC AGGGGCGCGC GCGCAGGGCC CAGGATGCCG CGGGGCTGGA CCGCGCTTTG CTTGCTGAGT TTGCTGC CCTTTTTTGG CCTCGACGGC GGCAACCCAG CCTCCCTCCT AACGCCCTCC GCCTTTGGGA CCAACCAGGG GAGCTCAAGT TAGTAGCAGC CAAGGAGAGG CGCTGCCTTG CCAAGACTAA AAAGGGAGGG GAGAAGAGAG GAAAAAAGCA AGAATCCCCC ACCCCTCTCC CGGGCGGAGG GGGCGGGAAG AGCGCGTCCT GGCCAAGCCG AGTAGTGTCT TCCACTCGGT GCGTCTCTCT AGGAGCCGCG CGGGAAGGAT GCTGGTCCGC

AGGGGCGCGC GCGAGGGCCC AGGATGCCGC GGGGCTGGAC CGCGCTTTGC TTGCTGAGTT TGCTGCCTTC TGGGTTCATG AGTGTTGACA ACAACGGTAC TGCTACCCCA GAGTTACCTA CCCAGGGAAC ATTTTCAAAT GTTTCTACAA ATGTATCCTA CCAAGAAACT ACAACACCTA GTACCCTTGG AAGTACCAGC CTGCACCCTG TGTCTCAACA TGGCAATGAG GCCACAACAA ACATCACAGA AACGACAGTC AAATTCACAT CTACCTCTGT GATAACCTCA GTTTATGGAA ACACAAACTC TTCTGTCCAG TCACAGACCT CTGTAATCAG CACAGTGTTC ACCACCCCAG CCAACGTTTC AACTCCAGAG ACAACCTTGA AGCCTAGCCT GTCACCTGGA AATGTTTCAG ACCTTTCAAC CACTAGCACT AGCCTTGCAA CATCTCCCAC TAAACCCTAT ACATCATCTT CTCCTATCCT AAGTGACATC AAGGCAGAAA TCAAATGTTC AGGCATCAGA GAAGTGAAAT TGACTCAGGG

CATCTGCCTG GAGCAAAATA AGACCTCCAG CTGTGCGGAG TTTAAGAAGG ACAGGGGAGA GGGCCTGGCC CGAGTGCTGT GTGGGGAGGA GCAGGCTGAT GCTGATGCTG GGGCCCAGGT ATGCTCCCTG CTCCTTGCCC AGTCTGAGGT GAGGCCTCAG TGTCTACTGC TGGTCTTGGC CAACAGAACA GAAATTTCCA GCAAACTCCA ACTTATGAAA AAGCACCAAT CTGACCTGAA AAAGCTGGGG ATCCTAGATT TCACTGAGCA AGATGTTGCA AGCCACCAGA GCTATTCCCA AAAGACCCTG ATTGCACTGG TCACCTCGGG AGGCCTGCTG GCTGTCTTGG GCATCACTGG CTATTTCCTG ATGAATCGCC GCAGCTGGAG CCCCACAGGA GAAAGGCTGG GCGAAGACCC TTATTACACG GAAAACGGTG GAGGCCAGGG CTATAGCTCA GGACCTGGGA CCTCCCCTGA GGCTCAGGGA AAGGCCAGTG TGAACCGAGG GGCTCAGAAA AACGGGACCG

GCCAGGCCAC CTCCAGAAAC GGCCATTCAG CAAGACAACA CGTGGTGGCT GATACCGAAT TGTGACTCGG CTAGGTGGGG CAAGGCTGGG CAGTGTCCGA GAGAGCACCC CTCTCTGCAT CTGACCACGT GCTACCCCCA TGCTGGAGGT GACATCTCTT ACGCCCAACC CTTCCCCACT GCACACACCT CAGAGGCTGT TCTTGGGGCC CTACACCTTG AGGAGGGGGC AGGTAAACTC CTGTCCTTTA CACATTCGGC TCCCTGGAGC CAGACTCTGG TCTTCTTTGG GTAAACGTGT GACGGGGGAA AGCCAAGGTC TGGAGAAGCT CCCAGGAACA ATCGATGGCC TTGCAGCACT CACACAGGAC CCCCTTCCCC TACCCCCTCC TCTCTGCCGC AATACAGGAA CCCCCAGGGG AAAGATGAGC TTTTCTAGGC TACAATTTTC TCCCAGGAAG CTTTGATTTT TACCGTTTCT TCCCTGTATT TTCTTTCTCT ACTTTGAGGA AACCAAAGTA ACCTTTTGCA CCTGCTCTCT

TGTAATGATA TAGCCAGAAA AACGTGTTGC CTTGAACCAC TTCCCTCATC TCTCCTCCAA GACACTGTGG ACTTGGTCAC CAGCTCCTCC CTTGTTCTCT AAGTTCCACT GAGCTCCATG TGCCCCCTCT ACCATTTGCA GAGTCCTGCA CAGTTTTCTG GCTGGAGCCT AGAACAGGCC TCCCAAGTTT TAGGACAAAC AGCTCAGTTC TAGTCTCTCT GGGGCCACAC AGAAACTCTT TTTGGGCTCC TTTTTCTCCC TCTGGATCAA AGTAGGCAGG ACCATGGGAC CAGGTCTTGG AGCTGAGCCT CTCACCTGTA CTCTTCCGAA AAATCCTCTT CCTCTGAGGC TGGATCCTAG CCTTATCCTC TGATCTCCAT GGCTTCCTCC TCCCTCCTGC CGACTCCTGG GTTGAGCTGT TGCCTCAGTC CCCCAACAGA TGCTTTTCTG TCTCTGCCTC CCTCACCCTG AGGCCCTTCC TTGCTCTGCA CCCCCATATG GTCATAGCCC AGATCAGCTC CTAACCCTTA TCACCAGCTG CCTCTTCTGT

GGGTGACCCA GGTCCTTGTT TGCTGTTGAT TTCTTTCCAG AGGGGTTGAG CAGGGATCCT GGTTTCAATG ACGGTTGGAA ATAGAAATTT CCAGAGAAGA GAGTATTGGG TAGATATTTT TTCTGAATAC AAAGTGATGT GTTTAAATAC TGCAATTAAA GTGATACTGA AACAC-3' (FRAG No J (SEQ DD NO 11835)

5'-AGGATGATGG TGATGGGGAA CTAAATGGGG AAATATGGAA GGTCACAGGA AAAGTTAACA CAAGTTAGCA AAAAGTTAAC ATAACACAAA AAGGTCTTGC AGGAAAAAAA AAAGAAAAGA AAAGAAAGAA AAAGTCTCCA AGAATGGTTT GGACAGCCAA AATGAATACT TATAGTCACG TATACCTGCT CACTCCTGAC GCTTCACTCA CACACAGCAC AGGATCTGGT GAGGCTATCA CTAAATGTGC CACATTGTGG TTAAGTTTTA CCTGATTAAC GAAATGCTCA CACTTCTAAA CTGAGGTCCT TACAGTAGAT TCCTTTTGCA AGATTGTTAC TGGCTTACAA CTTAAAAATA AAGGAAAATC ACAAGGAAAG AAAAGTGGGG AAAAAATCGG AGGAAACTTG CCCCTGCCCT GGCCACCGGC AAGGCTGCGA CAAAGGGGTT AAAAGTTAAG TGGAAGTGGA GCTTGAAGAA GTGGGATGGG GCCTCTCCAG GAAAGCTGAA CGAGGCATCT GGAGCCCGAA CAAACCTCCA CCTTTTTTGG CCTCGACGGC GGCAACCCAG CCTCCCTCCT AACGCCCTCC GCCTTTGGGA CCAACCAGGG GAGCTCAAGT TAGTAGCAGC CAAGGAGAGG CGCTGCCTTG CCAAGACTAA AAAGGGAGGG GAGAAGAGAG GAAAAAAGCA AGAATCCCCC ACCCCTCTCC CGGGCGGAGG GGGCGGGAAG AGCGCGTCCT

GGCCAAGCCG AGTAGTGTCT TCCACTCGGT GCGTCTCTCT AGGAGCCGCG CGGGAAGGAT GCTGGTCCGC AGGGGCGCGC GCGCAGGGCC CAGGATGCCG CGGGGCTGGA CCGCGCTTTG CTTGCTGAGT TTGCTGC 3' (FRAG NO J (SEQ DD NO 11833)

5'-CCTTTTTTGG CCTCGACGGC GGCAACCCAG CCTCCCTCCT AACGCCCTCC GCCTTTGGGA CCAACCAGGG GAGCTCAAGT TAGTAGCAGC CAAGGAGAGG CGCTGCCTTG CCAAGACTAA AAAGGGAGGG GAGAAGAGAG GAAAAAAGCA AGAATCCCCC ACCCCTCTCC CGGGCGGAGG GGGCGGGAAG AGCGCGTCCT GGCCAAGCCG AGTAGTGTCT TCCACTCGGT GCGTCTCTCT AGGAGCCGCG CGGGAAGGAT GCTGGTCCGC AGGGGCGCGC GCGAGOGCCC AGGATGCCGC

GGGGCTGGAC CGCGCTTTGC TTGCTGAGTT TGCTGCCTTC TGGGTTCATG AGTCTTGACA ACAACGGTAC TGCTACCCCA GAGTTACCTA CCCAGGGAAC ATTTTCAAAT GTTTCTACAA ATGTATCCTA CCAAGAAACT ACAACACCTA GTACCCTTGG AAGTACCAGC CTGCACCCTG TGTCTCAACA TGGCAATGAG GCCACAACAA ACATCACAGA AACGACAGTC AAATTCACAT CTACCTCTGT GATAACCTCA GTTTATGGAA ACACAAACTC TTCTGTCCAG TCACAGACCT CTGTAATCAG CACAGTGTTC ACCACCCCAG CCAACGTTTC AACTCCAGAG ACAACCTTGA AGCCTAGCCT GTCACCTGGA AATGTTTCAG ACCTTTCAAC CACTAGCACT AGCCTTGCAA CATCTCCCAC TAAACCCTAT ACATCATCTT CTCCTATCCT AAGTGACATC AAGGCAGAAA TCAAATGTTC AGGCATCAGA GAAGTGAAAT TGACTCAGGG CATCTGCCTG GAGCAAAATA AGACCTCCAG

CTGTGCGGAG TTTAAGAAGG ACAGGGGAGA GGGCCTGGCC CGAGTGCTGT GTGGGGAGGA GCAGGCTGAT GCTGATGCTG GGGCCCAGGT ATGCTCCCTG CTCCTTGCCC AGTCTGAGGT GAGGCCTCAG TGTCTACTGC TGGTCTTGGC CAACAGAACA GAAATTTCCA GCAAACTCCA ACTTATGAAA AAGCACCAAT CTGACCTGAA AAAGCTGGGG ATCCTAGATT TCACTGAGCA AGATGTTGCA AGGCACCAGA GCTATTCCCA AAAGACCCTG ATTGCACTGG TCACCTCGGG AGCCCTGCTG GCTGTCTTGG GCATCACTGG CTATTTCCTG ATGAATCGCC GCAGCTGGAG CCCCACAGGA GAAAGGCTGG GCGAAGACCC TTATTACACG GAAAACGGTG GAGGCCAGGG CTATAGCTCA GGACCTGGGA CCTCCCCTGA GGCTCAGGGA AAGGCCAGTG TGAACCGAGG GGCTCAGAAA AACGGGACCG GCCAGGCCAC CTCCAGAAAC GGCCATTCAG

CAAGACAACA CGTGGTGGCT GATACCGAAT TGTGACTCGG CTAGGTGGGG CAAGGCTGOG CAGTGTCCGA GAGAGCACCC CTCTCTGCAT CTGACCACGT GCTACCCCCA TGCTGGAGGT GACATCTCTT ACGCCCAACC CTTCCCCACT GCACACACCT CAGAGGCTGT TCTTGGGGCC CTACACCTTG AGGAGGGGGC AGGTAAACTC CTGTCCTTTA CACATTCGGC TCCCTGGAGC CAGACTCTGG TCTTCTTTGG GTAAACGTGT GACGGGGGAA AGCCAAGGTC TGGAGAAGCT CCCAGGAACA ATCGATGGCC TTGCAGCACT CACACAGGAC CCCCTTCCCC TACCCCCTCC TCTCTGCCGC AATACAGGAA CCCCCAGGGG AAAGATGAGC TTTTCTAGGC TACAATTTTC TCCCAGGAAG CTTTGATTTT TACCGTTTCT TCCCTGTATT TTCTTTCTCT ACTTTGAGGA AACCAAAGTA ACCTTTTGCA CCTGCTCTCT TGTAATGATA TAGCCAGAAA AACGTGTTGC CTTGAACCAC

TTCCCTCATC TCTCCTCCAA GACACTGTGG ACTTGGTCAC CAGCTCCTCC CTTGTTCTCT AAGTTCCACT GAGCTCCATG TGCCCCCTCT ACCATTTGCA GAGTCCTGCA CAGTTTTCTG GCTGGAGCCT AGAACAGGCC TCCCAAGTTT TAGGACAAAC AGCTCAGTTC TAGTCTCTCT GGGGCCACAC AGAAACTCTT TTTGGGCTCC TTTTTCTCCC TCTGGATCAA AGTAGGCAGG ACCATGGGAC CAGGTCTTGG AGCTGAGCCT CTCACCTGTA CTCTTCCGAA AAATCCTCTT CCTCTGAGGC TGGATCCTAG CCTTATCCTC TGATCTCCAT GGCTTCCTCC TCCCTCCTGC CGACTCCTGG GTTGAGCTGT TGCCTCAGTC CCCCAACAGA TGCTTTTCTG TCTCTGCCTC CCTCACCCTG AGCCCCTTCC TTGCTCTGCA CCCCCATATG GTCATAGCCC AGATCAGCTC CTAACCCTTA TCACCAGCTG CCTCTTCTGT GGGTGACCCA GGTCCTTGTT TGCTGTTGAT TTCTTTCCAG

AGGGGTTGAG CAGGGATCCT GGTTTCAATG ACGGTTGGAA ATAGAAATTT CCAGAGAAGA GAGTATTGGG TAGATATTTT TTCTGAATAC AAAGTGATGT GTTTAAATAC TGCAATTAAA GTGATACTGA AACAC-3' (FRAG No J (SEQ ID NO 11834)

Eotaxin Antisense Nucleic Acids and Oligonucleotide Fragments

5'-GCATTTTTTC AAGTTTTATG ATTTATTTAA CTTGTGGAAC AAAAATAAAC CAGAAACCAC CACCTCTCAC GCCAAAGCTC ACACCTTCAG CCTCCAACAT GAAGGTCTCC GCAGCACTTC TGTGGCTGCT GCTCATAGCA GCTGCCTTCA GCCCCCAGGG GCTCGCTGGG CCAGCTTCTG TCCCAACCAC CTGCTGCTTT AACCTGGCCA ATAGGAAGAT

ACCCCTTCAG CGACTAGAGA GCTACAGGAG AATCACCAGT GGCAAATGTC CCCAGAAAGC TGTGATCTTC AAGACCAAAC TGGCCAAGGA TATCTGTGCC GACCCCAAGA AGAAGTGGGT GCAGGATTCC ATGAAGTATC TGGACCAAAA ATCTCCAACT CCAAAGCCAT AAATAATCAC CATTTTTGAA ACCAAACCAG AGCCTGAGTG TTGCCTAATT TGTTTTCCCT TCTTACAATG CATTCTGAGG TAACCTCATT ATCAGTCCAA AGGGCATGGG TTTTATTATA TATATATATA χχ_Tχχχχχχχ AAAAAAAAAC GTATTGCATT TAATTTATTG AGGCTTTAAA ACTTATCCTC CATGAATATC AGTTATTTTT AAACTGTAAA GCTTTGTGCA GATTCTTTAC CCCCTGGGAG CCCCAATTCG ATCCCCTGTC ACGTGTGGGC AATGTTCCCC CTCTCCTCTC TTCCTCCCTG GAATCTTGTA AAGGTCCTGG CAAAGATGAT CAGTATGAAA ATGTCATTGT TCTTGTGAAC CCAAAGTGTG

ACTCATTAAA TGGAAGTAAA TGTTGTTTTA GGAATAC ATGAAGGTCT CCGCAGCACT TCTGTGGCTG CTGCTCATAG CAGCTGCCTT CAGCCCCCAG GGGCTCGCTG GGCCAGCTTC TGTCCCAACC ACCTGCTGCT TTAACCTGGC CAATAGGAAG ATACCCCTTC AGCGACTAGA GAGCTACAGG AGAATCACCA GTGGCAAATG TCCCCAGAAA GCTGTGATCT TCAAGACCAA ACTGGCCAAG GATATCTGTG CCGACCCCAA GAAGAAGTGG GTGCAGGATT CCATGAAGTA TCTGGACCAA AAATCTCCAA CTCCAAAGCC ATAA CCACATATTC CCCTCCTTTT CCAAGGCAAG ATCCAGATGG ATTAAAAAAT GTACCAAGTC CCTCCTACTA GCTTGCCTCT CTTCTGTTCT GCTTGACTTC CTAGGATCTG GAATCTGGTC AGCAATCAGG AATCCCTTCA TCGTGACCCC CGCATGGGCA AAGGCTTCCC TGGAATCTCC CACACTGTCT GCTCCCTATA AAAGGCAGGC

AGATGGGCCA GAGGAGCAGA GAGGCTGAGA CCAACCCAGA AACCACCACC TCTCACGCCA AAGCTCACAC CTTCAGCCTC CAACATGAAG GTCTCCGCAG CACTTCTGTG GCTGCTGCTC ATAGCAGCTG CCTTCAGCCC CCAGGGGCTC GCTGGGCCAG GTAAGCCCCC CAACTCCTTA CAGGAAAGGT AAGGTAACCA CCTCCAGGCT ACTAGGTCAG CAAGAATCTT TACAGACTCA CTGCAAATTC TCCATTTGAA AAATAGGGAA ACAGGTTTTG TGGGTGGACA AGAAATGCCT CAACCGTCAC ATCCAGTCAC TGGAAGAGCC AGAACTAGAA AGCTCCCGAG TCTTTTCCCC ACATTCAAGA GGGCCGCTGG GTGCATCCTT ACCCAGCTAT CCTTACAGTG TTTGGGAATG GGGAATGGCT CTGTCTTACT GTGGGCATGG TGGGCATTTT TGGCAGTGGG AGAGAAGGAA AATCTGTTGA TTAGAAGCTC AGTATGTTAA TTCGACTCCA GGACAGCTTT CAGAGACAGT GGCTAAGAGA

AGAACGAGGT CCCAGGGGAT CTCTTGAGGT GACTTATTTT GACACTCTTT GGGAAAGTTA TCTAGGAGAT TTGTTCCATA ACTCATTTTC CCATACTCTG GTGACAAATT TACTGAGTGT ATCGGTCCCA CTGAGCCAGT GCATAGCATG GTAACAAACA GTTCTAAATT ATCAATGACT TAACAGAATT AACTAAATTA ACAAAAGTTA CTTTCTCACT TGTACTAAAT ATCTATAATG TATGGGCTCA GGCTTCTGCA TTTTATACTC AGGATTCTAG ACTGATGGAG AAGTTGCCAT GTGGGGGAAC ATTGATGGAT ACTGTGATAA AGCAGAAGAA AGCTCTCAGG AGTCTTGCAT AGGCAATGCA CTGTGGCTCA AAAATGACAC CCATCACTTT GTCTCCTTCT TTATTGATCA AAACTAATTA ATGCCTCCAA CCAAACAAAA GTGGCCAAGA AATGCAAGTC TACCTTGTGT CTCAAAACAG AGGATGGAGA ATATTTGGTG AAAATTACCA TGACCATCAC ATGGCCACGT AGGTCTTTAT

AATGACAGAG CTAGCATTTG TCACATTGAC CAAGCTTTGT CCATACACTC TACAGTAATG ATGAGTCCTC AGTGCACAGG GGAGGATGCT GAAGACACAG GACAGCATCC TCCAGACACA TAAGACTTCA GAGCAGAGGG ATTCTCCCTC CACCTCTCGC AATTCCTTGC TTTCTCCTAA CTTCCTTTAC AAAGTCATGC TTGGAAATGT CTATGTATCA TCATGTGGCT CATTTTTTTC TCTGTTCATT TTTTTTCCCC AAAATTCAGC TTCTGTCCCA ACCACCTGCT GCTTTAACCT GGCCAATAGG AAGATACCCC TTCAGCGACT AGAGAGCTAC AGGAGAATCA CCAGTGGCAA ATGTCCCCAG AAAGCTGTGA TGTAAGTAAA TAAAGTTCAC CCTCCCCTAG ACAAAAAAAT AATGTCTAGG GCACAGAGTC AAGAACTGTG GGAGTCATAG ACTCTGATAG TTTGACCTCT ATGGTCCAAT TCATTAATTT TCACAAGTGA GTGTTCACTC CCAGCTCCCT GCCTGGGAGA TTGCTGTAGT

CATATCAATT TCTTCAAGTC AAGAGCAAAG ATGGTTTTAC TGGGCCTTTA AGAGCAGCAA CTAACCCAAG AGTCTCATCC TTCCTCCTCT CCGTAGCAAC CCTTTGTCCA GGGGCAGATG GTCCTTAAAT ATTTAGGGTC AAATGGGCAG AATTTTCAAA AACAATCCTT CCAATTGCAT CCTGATTCTC CCCACAGCTT CAAGACCAAA CTGGCCAAGG ATATCTGTGC CGACCCCAAG AAGAAGTGGG TGCAGGATTC CATGAAGTAT CTGGACCAAA AATCTCCAAC TCCAAAGCCA TAAATAATCA CCATTTTTGA AACCAAACCA GAGCCTGAGT GTTGCCTAAT TTGTTTTCCC TTCTTACAAT GCATTCTGAG GTAACCTCAT TATCAGTCCA AAGGGCATGG GTTTTATTAT ATATATATAT ATATATTTTT TTTTAAAAAA AAACGTATTG CATTTAATTT ATTGAGGCTT TAAAACTTAT CCTCCATGAA TATCAGTTAT TTTTAAACTG TAAAGCTTTG TGCAGATTCT TTACCCCCTG

GGAGCCCCAA TTCGATCCCC TGTCACGTGT GGGCAATGTT CCCCCTCTCC TCTCTTCCTC CCTGGAATCT TGTAAAGGTC CTGGCAAAGA TGATCAGTAT GAAAATGTCA TTGTTCTTGT GAACCCAAAG TGTGACTCAT TAAATGGAAG TAATGTTGTT TTAGGAATAC ATAAAGTATG TGCATATTTT ATTATAGTCA CTAGTTGTAA TTTTTTTGTG GGAAATCCAC ACTGAGCTGA GGGGG-3' (FRAGNO J (SEQ ID NO 11863) 5'-GCATTTTTTC AAGTTTTATG ATTTATTTAA CTTGTGGAAC AAAAATAAAC CAGAAACCAC CACCTCTCAC GCCAAAGCTC ACACCTTCAG CCTCCAACAT GAAGGTCTCC GCAGCACTTC TGTGGCTGCT GCTCATAGCA GCTGCCTTCA GCCCCCAGGG GCTCGCTGGG CCAGCTTCTG TCCCAACCAC CTGCTGCTTT AACCTGGCCA ATAGGAAGAT

ACCCCTTCAG CGACTAGAGA GCTACAGGAG AATCACCAGT GGCAAATGTC CCCAGAAAGC TGTGATCTTC AAGACCAAAC TGGCCAAGGA TATCTGTGCC GACCCCAAGA AGAAGTGGGT GCAGGATTCC ATGAAGTATC TGGACCAAAA ATCTCCAACT CCAAAGCCAT AAATAATCAC CATTTTTGAA ACCAAACCAG AGCCTGAGTG TTGCCTAATT TGTTTTCCCT TCTTACAATG CATTCTGAGG TAACCTCATT ATCAGTCCAA AGGGCATGGG TTTTATTATA TATATATATA χχχχχ_TTTχ AAAAAAAAAC GTATTGCATT TAATTTATTG AGGCTTTAAA ACTTATCCTC CATGAATATC AGTTATTTTT AAACTGTAAA GCTTTGTGCA GATTCTTTAC CCCCTGGGAG CCCCAATTCG ATCCCCTGTC ACGTGTGGGC AATGTTCCCC CTCTCCTCTC TTCCTCCCTG GAATCTTGTA AAGGTCCTGG CAAAGATGAT CAGTATGAAA ATGTCATTGT TCTTGTGAAC CCAAAGTGTG

ACTCATTAAA TGGAAGTAAA TGTTGTTTTA GGAATAC-3' (FRAG NO J (SEQ ID NO 11860)

5'-ATGAAGGTCT CCGCAGCACT TCTGTGGCTG CTGCTCATAG CAGCTGCCTT CAGCCCCCAG GGGCTCGCTG GGCCAGCTTC TGTCCCAACC ACCTGCTGCT TTAACCTGGC CAATAGGAAG ATACCCCTTC AGCGACTAGA GAGCTACAGG AGAATCACCA GTGGCAAATG TCCCCAGAAA GCTGTGATCT TCAAGACCAA ACTGGCCAAG GATATCTGTG CCGACCCCAA GAAGAAGTGG GTGCAGGATT CCATGAAGTA TCTGGACCAA AAATCTCCAA CTCCAAAGCC ATAA-3' (FRAG NO J (SEQ DD NO 11861) 5'-CCACATATTC CCCTCCTTTT CCAAGGCAAG ATCCAGATGG ATTAAAAAAT GTACCAAGTC CCTCCTACTA GCTTGCCTCT CTTCTGTTCT GCTTGACTTC CTAGGATCTG

GAATCTGGTC AGCAATCAGG AATCCCTTCA TCGTGACCCC CGCATGGGCA AAGGCTTCCC TGGAATCTCC CACACTGTCT GCTCCCTATA AAAGGCAGGC AGATGGGCCA GAGGAGCAGA GAGGCTGAGA CCAACCCAGA AACCACCACC TCTCACGCCA AAGCTCACAC CTTCAGCCTC CAACATGAAG GTCTCCGCAG CACTTCTGTG GCTGCTGCTC ATAGCAGCTG CCTTCAGCCC CCAGGGGCTC GCTGGGCCAG GTAAGCCCCC CAACTCCTTA CAGGAAAGGT AAGGTAACCA CCTCCAGGCT ACTAGGTCAG CAAGAATCTT TACAGACTCA CTGCAAATTC TCCATTTGAA AAATAGGGAA ACAGGTTTTG TGGGTGGACA AGAAATGCCT CAACCGTCAC ATCCAGTCAC TGGAAGAGCC AGAACTAGAA AGCTCCCGAG TCTTTTCCCC ACATTCAAGA GGGCCGCTGG GTGCATCCTT ACCCAGCTAT CCTTACAGTG TTTGGGAATG GGGAATGGCT CTGTCTTACT GTGGGCATGG

TGGGCATTTT TGGCAGTGGG AGAGAAGGAA AATCTGTTGA TTAGAAGCTC AGTATGTTAA TTCGACTCCA GGACAGCTTT CAGAGACAGT GGCTAAGAGA AGAACGAGGT CCCAGGGGAT CTCTTGAGGT GACTTATTTT GACACTCTTT GGGAAAGTTA TCTAGGAGAT TTGTTCCATA ACTCATTTTC CCATACTCTG GTGACAAATT TACTGAGTGT ATCGGTCCCA CTGAGCCAGT GCATAGCATG GTAACAAACA GTTCTAAATT ATCAATGACT TAACAGAATT AACTAAATTA ACAAAAGTTA CTTTCTCACT TGTACTAAAT ATCTATAATG TATGGGCTCA GGCTTCTGCA TTTTATACTC AGGATTCTAG ACTGATGGAG AAGTTGCCAT GTGGGGGAAC ATTGATGGAT ACTGTGATAA AGCAGAAGAA AGCTCTCAGG AGTCTTGCAT AGGCAATGCA CTGTGGCTCA AAAATGACAC CCATCACTTT GTCTCCTTCT TTATTGATCA AAACTAATTA ATGCCTCCAA CCAAACAAAA

GTGGCCAAGA AATGCAAGTC TACCTTGTGT CTCAAAACAG AGGATGGAGA ATATTTGGTG AAAATTACCA TGACCATCAC ATGGCCACGT AGGTCTTTAT AATGACAGAG CTAGCATTTG TCACATTGAC CAAGCTTTGT CCATACACTC TACAGTAATG ATGAGTCCTC AGTGCACAGG GGAGGATGCT GAAGACACAG GACAGCATCC TCCAGACACA TAAGACTTCA GAGCAGAGGG ATTCTCCCTC CACCTCTCGC AATTCCTTGC TTTCTCCTAA CTTCCTTTAC AAAGTCATGC TTGGAAATGT CTATGTATCA TCATGTGGCT CATTTTTTTC TCTGTTCATT TTTTTTCCCC AAAATTCAGC TTCTGTCCCA ACCACCTGCT GCTTTAACCT GGCCAATAGG AAGATACCCC TTCAGCGACT AGAGAGCTAC AGGAGAATCA CCAGTGGCAA ATGTCCCCAG AAAGCTGTGA TGTAAGTAAA TAAAGTTCAC CCTCCCCTAG ACAAAAAAAT AATGTCTAGG GCACAGAGTC AAGAACTGTG

GGAGTCATAG ACTCTGATAG TTTGACCTCT ATGGTCCAAT TCATTAATTT TCACAAGTGA GTGTTCACTC CCAGCTCCCT GCCTGGGAGA TTGCTGTAGT CATATCAATT TCTTCAAGTC AAGAGCAAAG ATGGTTTTAC TGGGCCTTTA AGAGCAGCAA CTAACCCAAG AGTCTCATCC TTCCTCCTCT CCGTAGCAAC CCTTTGTCCA GGGGCAGATG GTCCTTAAAT ATTTAGGGTC AAATGGGCAG AATTTTCAAA AACAATCCTT CCAATTGCAT CCTGATTCTC CCCACAGCTT CAAGACCAAA CTGGCCAAGG ATATCTGTGC CGACCCCAAG AAGAAGTGGG TGCAGGATTC CATGAAGTAT CTGGACCAAA AATCTCCAAC TCCAAAGCCA TAAATAATCA CCATTTTTGA AACCAAACCA GAGCCTGAGT GTTGCCTAAT TTGTTTTCCC TTCTTACAAT GCATTCTGAG GTAACCTCAT TATCAGTCCA AAGGGCATGG GTTTTATTAT ATATATATAT ATATATTTTT TTTTAAAAAA AAACGTATTG CATTTAATTT ATTGAGGCTT TAAAACTTAT CCTCCATGAA TATCAGTTAT TTTTAAACTG TAAAGCTTTG TGCAGATTCT TTACCCCCTG GGAGCCCCAA TTCGATCCCC TGTCACGTGT GGGCAATGTT CCCCCTCTCC TCTCTTCCTC CCTGGAATCT TGTAAAGGTC CTGGCAAAGA TGATCAGTAT GAAAATGTCA TTGTTCTTGT GAACCCAAAG TGTGACTCAT TAAATGGAAG TAATGTTGTT TTAGGAATAC ATAAAGTATG TGCATATTTT ATTATAGTCA CTAGTTGTAA TTTTTTTGTG GGAAATCCAC ACTGAGCTGA GGGGG-3' (FRAGNO J (SEQ DD NO 11862)

FK-500 Binding Protein Nucleic Acids and Oligonucleotide Fragments

5'- GCCAGGTCGC TGTTGGTCCA CGCCGCCCGT CGCGCCGCCC GCCCGCTCAG CGTCCGCCGC CGCCATGGGA GGCCGGAGCC GAGCCGGGGT CGGGCAGCAG CAGGGACCCC CCAGAGGCGG GGCCTGTGGG ACCGCTATGG GCGTGGAGAT CGAGACCATC TCCCCCGGAG ACGGAAGGAC ATTCCCCAAG AAGGGCCAAA CGTGTGTGGT GCACTACACA GGAATGCTCC AAAATGGGAA GAAGTTTGAT TCATCCAGAG ACAGAAACAA ACCTTTCAAG TTCAGAATTG GCAAACAGGA AGTCATCAAA GGTTTTGAAG AGGGTGCAGC CCAGATGAGC TTGGGGCAGA GGGCGAAGCT GACCTGCACC CCTGATGTGG CATATGGAGC CACGGGCCAC CCCGGTGTCA TCCCTCCCAA

TGCCACCCTC ATCTTTGACG TGGAGCTGCT CAACTTAGAG TGAAGGCAGG AAGGAACTCA AGGTGGCTGG AGATGGCTGC TGCTCACCCT CCTAGCCTGC TCTGCCACTG GGACGGCTCC TGCTTTTGGG GCTCTTGATC AGTGTGCTAA CCTCACTGCC TCATGGCATC ATCCATTCTC TCTGCCCAAG TTGCTCTGTA TGTGTTCGTC AGTGTTCATG CGAATTCTTG CTTGAGGAAA CTTCGGTTGC AGATTGAAGC ATTTCAGGTT GTGCATTTTG TGTGATGCAT GTAGTAGCCT TTCCTGATGA CAGAACACAG ATCTCTTGTT CGCACAATCT ACACTGCCTT ACCTTCACTT AAACCACACA CACAAGGTGC TCAGACATGA AATGTACATG GCGTACCGTA CACAGAGGGA CTTGAGCCAG TTACCTTTGC TGTCACTTTC TCTCTTATAA ATTCTGTTAG CTGCTCACTT AAACAATGTC CTCTTTGAGA AAATGTAAAA TAAAGGCTCT GTGCTTGACA GAATTCGGGC CGCCGCCAGG

TCGCTGTTGG TCCACGCCGC CCGTCGCGCC GCCCGCCCGC TCAGCGTCCG CCGCCGCCAT GGGAGTGCAG GTGGAAACCA TCTCCCCAGG AGACGGGCGC ACCTTCCCCA AGCGCGGCCA GACCTGCGTG GTGCACTACA CCGGGATGCT TGAAGATGGA AAGAAATTTG ATTCCTCCCG GGACAGAAAC AAGCCCTTTA AGTTTATGCT AGGCAAGCAG GAGGTGATCC GAGGCTGGGA AGAAGGGGTT GCCCAGATGA GTGTGGGTCA GAGAGCCAAA CTGACTATAT CTCCAGATTA TGCCTATGGT GCCACTGGGC ACCCAGGCAT CATCCCACCA CATGCCACTC TCGTCTTCGA TGTGGAGCTT CTAAAACTGG AATGACAGGA ATGGCCTCCT CCCTTAGCTC CCTGTTCTTG GATCTGCCAT GGAGGGATCT GGTGCCTCCA GACATGTGCA CATGAGTCCA TATGGAGCTT TTCCTGATGT TCCACTCCAC TTTGTATAGA CATCTGCCCT GACTGAATGT GTTCTGTCAC TCAGCTTTGC

TTCCGACACC TCTGTTTCCT CTTCCCCTTT CTCCTCGTAT GTGTGTTTAC CTAAACTATA TGCCATAAAC CTCAAGTTAT TCATTTTATT TTGTTTTCAT TTTGGGGTGA AGATTCAGTT TCAGTCTTTT GGATATAGGT TTCCAATTAA GTACATGGTC AAGTATTAAC AGCACAAGTG GTAGGTTAAC ATTAGAATAG GAATTGGTGT TGGGGGGGGG GTTTGCAAGA ATATTTTATT TTAATTTTTT GGATGAAATT TTTATCTATT ATATATTAAA CATTCTTGCT GCTGCGCTGC AAAGCCATAG CAGATTTGAG GCGCTGTTGA GGACTGAATT ACTCTCCAAG TTGAGAGATG TCTTTGGGTT AAATTAAAAG CCCTACCTAA AACTGAGGTG GGGATGGGGA GAGCCTTTGC CTCCACCATT CCCACCCACC CTCCCCTTAA ACGCTCTGCC TTTGAAAGTA GATCATGTTC ACTGCAATGC TGGACACTAC AGGTATCTGT CCCTGGGCCA GCAGGGACCT CTGAAGCCTT CTTTGTGGCC

TTTTTTTTTT TTCATCCTGT GGTTTTTCTA ATGGACTTTC AGGAATTTTG TAATCTCATA ACTTTCCAAG CTCCACCACT TCCTAAATCT TAAGAACTTT AATTGACAGT TTCAATTGAA GGTGCTGTTT GTAGACTTAA CACCCAGTGA AAGCCCAGCC ATCATGACAA ATCCTTGAAT GTTCTCTTAA GAAAATGATG CTGGTCATCG CAGCTTCAGC ATCTCCTGTT TTTTGATGCT TGGCTCCCTC TGCTGATCTC AGTTTCCTGG CTTTTCCTCC CTCAGCCCCT TCTCACCCCT TTGCTGTCCT GTGTAGTGAT TTGGTGAGAA ATCGTTGCTG CACCCTTCCC CCAGCACCAT TTATGAGTCT CAAGTTTTAT TATTGCAATA AAAGTGCTTT ATGCCCGAAT TC GCCGCCGCCA TGGGAGTGCA GGTGGAAACC ATCTCCCCAG GAGACGGGCG CACCTTCCCC AAGCGCGGCC AGACCTGCGT GGTGCACTAC ACCGGGATGC TTGAAGATGG AAAGAAATTT GATTCCTCCC

GGGACAGAAA CAAGCCCTTT AAGTTTATGC TAGGCAAGCA GGAGGTGATC CGAGGCTGGG AAGAAGGGGT TGCCCAGATG AGTGTGGGTC AGAGAGCCAA ACTGACTATA TCTCCAGATT ATGCCTATGG TGCCACTGGG CACCCAGGCA TCATCCCACC ACATGCCACT CTCGTCTTCG ATGTGGAGCT TCTAAAACTG GAATGACAGG AATGGCCTCC TCCCTTAGCT CCCTGTTCTT GGATCTGCCR TGGAGGGATC TGGTGCCTCC AGACATGTGC ACATGARTCC ATATGGAGCT TTTCCTGATG TTCCACTCCA CTTTGTATAG ACATCTGCCC TGACTGAATG TGTTCTGTCA CTCAGCTTTG CTTCCGACAC CTCTGTTTCC TCTTCCCCTT TCTCCTCGTA TGTGTGTTTA CCTAAACTAT ATGCCATAAA CCTCAAGTTA TTCA-3' (FRAGNO J (SEQ DD NO 11868)

5'- GCCAGGTCGC TGTTGGTCCA CGCCGCCCGT CGCGCCGCCC GCCCGCTCAG CGTCCGCCGC CGCCATGGGA-3' (FRAG No J(SEQ ID NO 11864)

5'-GGCCGGAGCC GAGCCGGGGT CGGGCAGCAG CAGGGACCCC CCAGAGGCGG GGCCTGTGGG CCGCTATGG GCGTGGAGAT CGAGACCATC TCCCCCGGAG ACGGAAGGAC ATTCCCCAAG AAGGGCCAAA CGTGTGTGGT GCACTACACA GGAATGCTCC AAAATGGGAA GAAGTTTGAT TCATCCAGAG ACAGAAACAA ACCTTTCAAG TTCAGAATTG GCAAACAGGA AGTCATCAAA GGTTTTGAAG AGGGTGCAGC CCAGATGAGC TTGGGGCAGA GGGCGAAGCT GACCTGCACC CCTGATGTGG CATATGGAGC CACGGGCCAC CCCGGTGTCA TCCCTCCCAA TGCCACCCTC ATCTTTGACG TGGAGCTGCT CAACTTAGAG TGAAGGCAGG AAGGAACTCA AGGTGGCTGG

AGATGGCTGC TGCTCACCCT CCTAGCCTGC TCTGCCACTG GGACGGCTCC TGCTTTTGGG GCTCTTGATC AGTGTGCTAA CCTCACTGCC TCATGGCATC ATCCATTCTC TCTGCCCAAG TTGCTCTGTA TGTGTTCGTC AGTGTTCATG CGAATTCTTG CTTGAGGAAA CTTCGGTTGC AGATTGAAGC ATTTCAGGTT GTGCATTTTG TGTGATGCAT GTAGTAGCCT TTCCTGATGA CAGAACACAG ATCTCTTGTT CGCACAATCT ACACTGCCTT ACCTTCACTT AAACCACACA CACAAGGTGC TCAGACATGA AATGTACATG GCGTACCGTA CACAGAGGGA CTTGAGCCAG TTACCTTTGC TGTCACTTTC TCTCTTATAA ATTCTGTTAG CTGCTCACTT AAACAATGTC CTCTTTGAGA AAATGTAAAA TAAAGGCTCT GTGCTTGACA-3'(FRAG NO J (SEQ ID NO 12487)

5'-GAATTCGGGC CGCCGCCAGG TCGCTGTTGG TCCACGCCGC CCGTCGCGCC GCCCGCCCGC TCAGCGTCCG CCGCCGCCAT GGGAGTGCAG GTGGAAACCA TCTCCCCAGG AGACGGGCGC ACCTTCCCCA AGCGCGGCCA GACCTGCGTG GTGCACTACA CCGGGATGCT TGAAGATGGA AAGAAATTTG ATTCCTCCCG GGACAGAAAC AAGCCCTTTA AGTTTATGCT AGGCAAGCAG GAGGTGATCC GAGGCTGGGA AGAAGGGGTT GCCCAGATGA GTGTGGGTCA GAGAGCCAAA CTGACTATAT CTCCAGATTA TGCCTATGGT GCCACTGGGC ACCCAGGCAT CATCCCACCA CATGCCACTC TCGTCTTCGA TGTGGAGCTT CTAAAACTGG AATGACAGGA ATGGCCTCCT CCCTTAGCTC CCTGTTCTTG GATCTGCCAT GGAGGGATCT GGTGCCTCCA GACATGTGCA CATGAGTCCA TATGGAGCTT TTCCTGATGT TCCACTCCAC TTTGTATAGA CATCTGCCCT

GACTGAATGT GTTCTGTCAC TCAGCTTTGC TTCCGACACC TCTGTTTCCT CTTCCCCTTT CTCCTCGTAT GTGTGTTTAC CTAAACTATA TGCCATAAAC CTCAAGTTAT TCATTTTATT TTGTTTTCAT TTTGGGGTGA AGATTCAGTT TCAGTCTTTT GGATATAGGT TTCCAATTAA GTACATGGTC AAGTATTAAC AGCACAAGTG GTAGGTTAAC ATTAGAATAG GAATTGGTGT TGGGGGGGGG GTTTGCAAGA ATATTTTATT TTAATTTTTT GGATGAAATT TTTATCTATT ATATATTAAA CATTCTTGCT GCTGCGCTGC AAAGCCATAG CAGATTTGAG GCGCTGTTGA GGACTGAATT ACTCTCCAAG TTGAGAGATG TCTTTGGGTT AAATTAAAAG CCCTACCTAA AACTGAGGTG GGGATGGGGA GAGCCTTTGC CTCCACCATT CCCACCCACC CTCCCCTTAA ACCCTCTGCC TTTGAAAGTA GATCATGTTC ACTGCAATGC TGGACACTAC AGGTATCTGT CCCTGGGCCA

GCAGGGACCT CTGAAGCCTT CTTTGTGGCC χχχ_TTTTχχ_T TTCATCCTGT GGTTTTTCTA ATGGACTTTC AGGAATTTTG TAATCTCATA ACTTTCCAAG CTCCACCACT TCCTAAATCT TAAGAACTTT AATTGACAGT TTCAATTGAA GGTGCTGTTT GTAGACTTAA CACCCAGTGA AAGCCCAGCC ATCATGACAA ATCCTTGAAT GTTCTCTTAA GAAAATGATG CTGGTCATCG CAGCTTCAGC ATCTCCTGTT TTTTGATGCT TGGCTCCCTC TGCTGATCTC AGTTTCCTGG CTTTTCCTCC CTCAGCCCCT TCTCACCCCT TTGCTGTCCT GTGTAGTGAT TTGGTGAGAA ATCGTTGCTG CACCCTTCCC CCAGCACCAT TTATGAGTCT CAAGTTTTAT TATTGCAATA AAAGTGCTTT ATGCCCGAAT TC-3' (FRAG NO J (SEQ ID NO 11866)

5' GCCGCCGCCA TGGGAGTGCA GGTGGAAACC ATCTCCCCAG GAGACGGGCG CACCTTCCCC AAGCGCGGCC AGACCTGCGT GGTGCACTAC ACCGGGATGC TTGAAGATGG AAAGAAATTT GATTCCTCCC GGGACAGAAA CAAGCCCTTT AAGTTTATGC TAGGCAAGCA GGAGGTGATC CGAGGCTGGG AAGAAGGGGT TGCCCAGATG AGTGTGGGTC AGAGAGCCAA ACTGACTATA TCTCCAGATT ATGCCTATGG TGCCACTGGG CACCCAGGCA TCATCCCACC ACATGCCACT CTCGTCTTCG ATGTGGAGCT TCTAAAACTG GAATGACAGG AATGGCCTCC TCCCTTAGCT CCCTGTTCTT GGATCTGCCR TGGAGGGATC TGGTGCCTCC AGACATGTGC ACATGARTCC ATATGGAGCT TTTCCTGATG TTCCACTCCA CTTTGTATAG ACATCTGCCC TGACTGAATG TGTTCTGTCA CTCAGCTTTG CTTCCGACAC CTCTGTTTCC TCTTCCCCTT

TCTCCTCGTA TGTGTGTTTA CCTAAACTAT ATGCCATAAA CCTCAAGTTA TTCA-3' (FRAG NO _) (SEQ ID NO 11867) wherein B is adenosine, or, more preferably, replaces adenos e and is an "equivameWlent" or a "universal" base, and adenosine A_2a receptor agonist or only minimally antagonist, an adenosine A_2D receptor antagonist, an adenosine A₃ receptor antagonist, or an adenosine Ai receptor antagonist. Similarly, adenosine (A) may always be replaced by an "alternative", "equivalent" and/or "universal" base having a small fraction, preferably less than 0.3 of the activity of adenosine at the adenosine receptor(s), as described above. More sequences of examples below gtttcgctcttgttgccc (SEQ ID NO: 11031) gccgcccgcctg(SEQ_ ID NO: 11051) gcccgctccccggc (SEQ ID NO:110Ξ₂) cbccgbggbgccc (SEQ ID NO: 11053) ggcgccgtgccgcgtcttggtggcggcgggttcgcgcccgcgcggggcccctccggtccgttcgcgcccgcgcggggoccctccggtcccgggtcgg ggccccccgcggccgcctcggggctggggcgctggtggccgggccgcgcctccgcctgccgcttctggctgggccccgggcgccccctcccctcttg ctcgggtccccgtgacagcgcgtcctgtgtctccagcagcatggccgggccagctgggccccbcbgcgcgtcctgtgtctccbgcbgcbtggccggg ccbgctgggcccc (SEQ ID NO:1105 ) acagagcagtgctgttgttgggcatcttgccttcccagggbcbgbgcbtgctgttgttgggcbtcttgccttcccbgggcccttttctggtggggtg gtgctgttgttgggctttcttctgttcccbcbgbgcbgtgctgttgttgggcbtcttgccttcccbgggcccttttctggtggggtggtgctgttgt tgggct ttcttctgttccc (SEQ ID NO: 11059) gcctgtgtctgtcctcctgcttcgttcctctcgttcctgcttggtgcccttgccggtcctgctcctccgggctgtgggtcctcgccctggctccggc tggtgggctcccctggccttcgctggctggcggcgtgccccbgbbcgbgbcccggbccgbcbggccgtggttgggggtcttcgctgcctccgtttgg gtggcgatctctgaatattgaccttccatggcggtcctgcttggagbtctctgbbtbttgbccttccbtggcggtcctgcttggbtcgttcctctcg

(SEQ ID NO:11079) gcgctcggcctggtcccgggggtctcctcttgttgttgcttgcgcctcctgctgggggtccctctgttcttgttttgggggcgggcccggccgttgt cttggtttgggggtttccgttggggttctcctggcccgggccttgcccggccgtggtcccggcttcgttcctgtctccgtctcggctcttctggggc cttgcgctgtctttggtggcbccgtccbgtgbtggtgcggtbcttgtcgctgcbgcgctcggcctggtcccggbgbgc (SEQ ID NO: 11108) bbgtgbgbgctgbgbgbbbctgtgbbgcbbtcbtgbcttcbbgbgttcttttcbcccgttcttggcttcttctgtccgttggcttctcgttgtccct gtgggcttctcgttgtccccccttcgggggctggtggggccgtccttgcctgctgggttcttggcttcttctgtccgttggcttctcgttgtccctg tgggct tctcgttgtccccccttcgggggctggtggggccgtccttgcctgctgg (SEQ ID NO:111 0) ccggggctgcbgcbbcctcbtcbgctcttgcctggbgtggctcbgcctgggcctgcbgggccbccbggbgbbtggcbgcbbggbtggcgbgggtcct cbtggctggggtcbcbgbtcctctbgctbggcbgggtgbccbgbgbgggcgggtcctcbtggctgggggcctgggcctgcbgggccgctcttgcctg gbgtgg ctcgcccbgbgtcttccctggt (SEQ ID NO: 11181) cgctgcbbtctgctccggggctgcbgcbbcctcbtcbgctcttgcctggbgtggctcbgcctgggcctgcbgggccbccbggbgbbtggcbgcbbgg btggcgbgggtcctcbtggctggggtcbcctggbggbgggbgbgcbgggggtcctcbtggctggggtccctctctcccgtcct (SEQ ID

NO:11186) ggbgctgbtbctgcbgatttcbgbgggbbgbbccctgbtbctcbccbgcttcbgctctggbgcbcbbgbgbbbgbgcbgcbgggggbgbggbbgbbg cbgcbtcttcccbgbgbggctgccgbgcbbbtgctggttttcctttccbgtctTgggttttbtbbctcccbgbbggcbbgbgbggggcbbggcgttt tcttctctcgctggttttcctttcctggcagtgggtgggggtgggggtggggtggcttccttgttcctgggggtgtcctcttgctctgggcttttct ccccttttccttcctgtctgttttcctggggctctcctctgtctctgtgtccttgccctggccctcttccctctcctgtctcctgtccctgtgttcc gcccgtcttccctctcctgacctccttttcctccgctgggtggggccctgcctgttctctgctccctggcttggggtttcttctgtgtgtcttcttc ctctgttggctggctttctccttcttttgtcttcctgggtgccccttcttcctttcttgggtcct tggtgcttgggotggg (SEQ ID

NO:11269) ctgccccbgtttttgbtcctcbcbtgccgtggggbggbcbbtggctgcctccccggggtttctgctgcttgctgcttctttcccgtctcccttcttt cccgtctcctttttgcctctttgggttcctgttgtttctggcctgcttggtggcggcttgtgcgtttcctctctcttctottgggtctccgcttctc gtcctgccttttcctgtctctgtcgcgccgttcctcctccggcgtcctcctgccctgtgctgtttgcctcgggtggtgcgggtcccggtgctccccc ggcgggccggctggttgcctgggcctgtctggtggggtgtggggccgctgggttgggggtgtggtgggctcttctgtggcctgtggggctgttggtg tctctgtgggcgtgtgctgggtcttggggcttcctcccttgtgctgggtgcggcctccccgccccccttctgggccggtggcctggctccttgtggg cgcttctggctcttgccctgtccttcttcgcctcgtggctgctgggctgc (SEQ ID NO: 11279) ggtgbcbttgbgcbtgtcggcgcggtcccgttbbgbgtgggcccgccagcccagccactccacttgggggcgggtggccagcacgaacagcacccag aggaaggggggcggcccagaagggcagcccgcaggccaggatcaggtctgctgcggccggagataatggcattcaccacgcggcggcccagcgcacg ccgcgcatccggcccgggttctgacctgcagcccccgtctccttggcattcctgggccccagtcactcctctccctgccccccttgctggggcaggg acggggtgbcbttgbgcbtgtcggcgcggtcccgttbbgbgtgggcccgccagcccagccactccacttgggggcgggtggccagcacgaacagcac ccagaggaaggggggcggcccagaagggcagcccgcaggccaggatcaggtctgctgcggccggagataatggcattcaccacgcggcggcccagcg cacgccgcgcatccggcccgggttctgacctgcagcccccgtctccttggcattcctgggccccagtcactcctctccctgccccccttgctggggc agggacggccgtgttgtcbgtggtgctgcccgtttgbggtbtggcgctccbccbbttcccttttctcc ttgttttccgtttctcttgccgtctgtggtt (SEQ ID NO: 11657) cccggccccgcctcgtgcc (SEQ ID NO:11685) cgtccbtgccgcgggccc (SEQ ID NO:11686) gccccgctgcttgggctgctctgccggg (SEQ ID NO: 11687) tctgtgctcctctcgcctggg(SEQ ID NO: 11688) tggtggggtgggtcttggtgg (SEQ ID NO: 11689) ctgtccctggtcctgtg (SEQ ID NO:11690) ggtcccgcttcttc (SEQ ID NO: 11691) ggggttgttgttggtctgg (SEQ ID NO: 11692) tgtcctctttctgc (SEQ ID NO: 11693) gcctcgggcctccc (SEQ ID NO:11694) ggctggggtctgcg (SEQ ID NO: 11695) ggccgggggtcggtgggtccgctg (SEQ ID NO: 11696) gggctggggtgctggcttgggg (SEQ ID NO: 11697) ggggctggggcctgggcc (SEQ ID NO: 11698) gcctgggtgggcttgggggc (SEQ ID NO: 11699) gctgggtctgtgctgttgcc (SEQ ID NO: 11700) gttgtgtggggggcc (SEQ ID NO: 11701) gctgggtcggggggcctctgggctgtc (SEQ ID NO: 11702) gccccggggccccc (SEQ ID NO: 11703) tggctcccccctcc (SEQ ID NO: 11704) gctCCCCCCtttCC (SEQ ID NO: 11705) cggacgaagacagaga (SEQ ID NO: 11706) ggctttgtgggctc (SEQ ID NO-.11707) gcctgctctCCCCC (SEQ ID NO: 11708) cccggccccgccbcgbbcc (SEQ ID NO: 11709) cccggccccgccbcg (SEQ ID NO: 11710) cccggccccgccbcgbbcc (SEQ ID NO:11711) cccggccccgccbcg (SEQ ID NO: 11712) cccgbccccgcctcbbg (SEQ ID NO: 11713) cccgbccccgcctc (SEQ ID NO: 11714) ccggccccgcctc (SEQ ID NO: 11715) cccgbbcccgcbtbgtgcc (SEQ ID NO: 11716) cccgcbtbgtgcc (SEQ ID NO: 11717) cccggbcccbccbbgtgcc (SEQ ID NO: 11718) cbgbbcccgcctcgtgcc (SEQ ID NO: 11719) cccgcctcgtgcc (SEQ ID NO:11720) ccggcbccgcctcbtgcc (SEQ ID NO: 11721) ccggccccgccbcbtgcc (SEQ ID NO: 11722) cccgbccccgbctcg (SEQ ID NO: 11723) cccggccbcgbctcg (SEQ ID NO: 11724) cccggcccbgcctbg (SEQ ID NO: 11725) cccggcbcbgbctcgtbcc (SEQ ID NO: 11726) cccggccccgccbcg (SEQ ID NO:11727) cccggccccgccbcg (SEQ ID NO: 11728) tccbtgccgcgggc (SEQ ID NO: 11729) tccbtgccbcgggcc (SEQ ID NO: 11730) tccbtgccbcgggcc (SEQ ID NO: 11731) tccbtgccbcbggcc (SEQ ID NO: 11732) gtccbtgbcgcgg (SEQ ID NO -.11733) tccbtgbcgcggg (SEQ ID NO: 11734) tctgbgctcctctbbcctggg (SEQ ID NO: 11735) ctgtgcbcctbbcbcctggg (SEQ ID NO: 11736) tgtgbtccbctbgbctggg (SEQ ID NO.-11737) tctgtbctcbbctcbcctg (SEQ ID NO:11738) tgctcctcbcbbctggg (SEQ ID NO: 11739) ctcctctbgcctgg (SEQ ID NO:11740) gtgctccbbtcbbctggg (SEQ ID NO: 11741) gtgcbccbbtcbcctggg (SEQ ID NO: 11742) tctgtgcbcctctbgbct (SEQ ID N0:1174₃) tbbtcctbbcbcctgg (SEQ ID NO: 11744) tgtgctbbtcbcbcbtggg (SEQ ID NO: 11745) gtgcbccbctcbcctg (SEQ ID NO: 11746) ctgtgcbcctctc (SEQ ID NO: 11747) cbgtgcbccbctcbcctg (SEQ ID NO.-11748) gtgcbccbctcbcctg (SEQ ID NO: 11749) cbcctctcbcctggg (SEQ ID NO: 11750) cctctcbcctggg (SEQ ID NO: 11751) gctccbctcgcct (SEQ ID NO: 11752) tgctcctcbcgcc (SEQ ID NO: 11753) gttgttgbtctgg (SEQ ID NO: 11754) ggttgbbbttggtcttgg (SEQ ID NO: 11755) ggttgttgbtgbtctg (SEQ ID NO: 11756) gggttbbbgttgbtctgg (SEQ ID NO: 11757) gggttbbbgttgbtctgg (SEQ ID NO: 11758) ttgttgtbgbtctgg (SEQ ID NO.-11759) gggtbgbbgbgtccgctg (SEQ ID NO:11760) gggtcbgbggbtcbgctg (SEQ ID NO: 11761) gggtbggtgggtc (SEQ ID NO -.11762) gggtcggbgggtcbgc (SEQ ID NO: 11763) cctgggtgggctt (SEQ ID NO: 11764) gggtgggcttggg (SEQ ID NO: 11765) cctgggtgggbbtggg (SEQ ID NO: 11766) cctggbtgggcbtggg (SEQ ID NO: 11767) gcctgbgtgbbcttggg (SEQ ID NO: 11768) ggcggcctggaaagctgagatggagggcggcatggcgggcacaggctgggctgcttttcttttctgggcctctgtggtct gtttttttctggccctgctggggcgctctccgccgcccgcctggctcccggbgcccbtgbtgggcbtgccgtggttcttg ccctcctttggctgccgtgcccgctccccggcctcctggcgggtggccgttgggcccgtgttcccctggggcctggggct cccttctctcgcccttcttgctgggcctctgctgctgctggtgctgtggcccccgtacaccgaggagcccatgatgggca tgccacagacgacaggcgtbcbccgbggbgcccbtgbtgggcbtgccbcbgbcgbcbggcggcgccgtgccgcgtcttgg tggcggcgggttcgcgcccgcgcggggcccctccggtccgttcgcgcccgcgcggggcccctccggtcccgggtcggggc cccccgcggccgcctcggggctggggcgctggtggccgggccgcgcctccgcctgccgcttctggctgggccccgggcgc cccctcccctcttgctcgggtccccgtgacagcgcgtcctgtgtctccagcagcatggccgggccagctgggccccbcbg cgcgtcctgtgtctccbgcbgcbtggccgggccbgctgggccccacagagcagtgctgttgttgggcatcttgccttccc agggbcbgbgcbtgctgttgttgggcbtcttgccttcccbgggcccttttctggtggggtggtgctgttgttgggctttc ttctgttcccbcbgbgcbgtgctgttgttgggcbtcttgccttcccbgggcccttttctggtggggtggtgctgttgttg ggctttcttctgttccctttcccctgggtcttccctcctgctcttttttcatttgctctcctattactttctgtgtccat tttttcattaaccgagctgtbtttgctctcctbttbctttctgtgtccbttttttcbttbbccgbgctgtgcctgtgtct gtcctcctgcttcgttcctctcgttcctgcttggtgcccttgccggtcctgctcctccgggctgtgggtcgtggccctgg ctccggctggtgggctcccctggccttcgctggctggcggcgtgcgggtcttgctctgggcctggctgtggccgtggttg ggggtcttcgctgcctccgtttgggtggctctctgaatattgaccttcctccatggcggtcctgcttggattctcccgat ctctgbbtbttgbccttcctccbtggcggtcctgcttggbttctcccgbgcctttcctggttctcttgttgtttttgggg tttggcttacagtagagtaggggattccatggcaggagccatcttcttcatggactccttcaaggagaccttaggtttct gagggactgctaacacgccatctggagcbcbgtbgbgtbggggbttccbtggcbggbgccbtcttcttcbtggbctcctt cbbggbgbccttbggtttctgbgggbctgctbbcbcgccbtctggbgcgttgtttttggggtttggcttgcctttcctgg ttctcttbcbgtbgbgtbggggbttccbtggcbggbgccbtcttcttcbtggbctccttcbbggbgbccttbggtttctg bgggbctgctbbcbcgccbtctggbgcgcctgtgtctgtcctcctgcttcgttcctctcgttcctgcttggtgcccttgc cggtcctgctcctccgggctgtgggtcctcgccctggctccggctggtgggctcccctggccttcgctggctggcggcgt gccccbgbbcgbgbcccggbccgbcbggccgtggttgggggtcttcgctgcctccgtttgggtggcgatctctgaatatt gaccttccatggcggtcctgcttggagbtctctgbbtbttgbccttccbtggcggtcctgcttggbtctggggtgtcctg gccttcgtggttcctcttccttcgtttgccgtccgcgggggcccccgggcctggctgcgctcctgccccgcctctttccc gggctcttgcgctggggggtgctcccgtgtgtttgcgccctcctcctggtcgcgcttgtcgttttggggccggctttgcc cgcctcccggcgcctggcccggccttcctgggctgcgtgcgcgttctgttcttcttcctggctctggggtgtcctggcct tcgtggttcctcttccttcgtttgccgtccgcgggggcccccgggcctggctgcgctcctgccccgcctctttcccgggc tcttgcgctggggggtgctcccgtgtgtttgcgccctcctcctggtcgcgcttgtcgttttggggccggctttgcccgcc tcccggcgcctggcccggccttcctgggctgcgtgcgcgttctgttcttcttcctggcgcaggagacagggcagggcgat caggagcagcgtgagccaaaggaggaccatcgggaacgcagctccggaacgcaggacagaggtgccgcbggbgbcbgggc bgggcgbtcbggbgcbgcgtgbgccbbbggbggbccbtcgggbbcgcbgctccggbbcgcbggbcbgbggtgcctctgcc ctgtccgccggctcttcggtggctcggccccgctccttgtcttgccgcgggttggttcctgggcctggttcttgcgggcg tttcggtctgctggctggtctgggcccgcggtgcggcgggtggcttgctgttctgcctgggctctcccctctcctccttt tctcccttcctctgtcttgcctccttcctctgggtcctcttggcctgggcgctcttcccctcgggcggctgcgggcgctc gtgctgcctggtccgctccctgggggtgctccttccctttccccgctcgtggggtttgcggggctgggctgccctggggg gtctgggccttttggggtcggctggctgctgcttcgggccgcctgggcttccctgtgcccctttcctctgctgggtcccc ctcccgttccaagctgcaccgcacagaccggcgctacaggacagagccaggcaagcacccatggggatccaggcccagct gttccbbgctgcbccgcbcbgbccggcgctbcbggbcbgbgccbggcbbgcbcccbtggggbtccbggcccbgctgctca gtggcccccaaaaggatgagtaatacatgcgccacgatgatcatatcctttttactatgaggccgtgtctgtcgtgtctt tcctttgctcttggtgtgtctttgctgtgccctgcctctctgcccgtgtctgtcgtgtctttcctttgctcttggtgtgt ctttgctgtgccctgcctctctgcccgtgtctgtcgtgtctttcctttgctcttggtgtgtctttgctgtgccctgcctc tctgcgggggtggcttcctgccgcgtctctgggccgtcccgtccctcggccccgcgccgcgctcggctcctctccctctg gcccggctcggggcggggcggggcggtgggcgggcggcgctgccctgcgcgcggcgctggcccctgctggccgtcggctg cgcgctgctggctgccctgctggccgcgccggggcctgtccgcctctgcgggcgctgtctcctggcttgtcttccggctc ttctgctggggtggggctgggcggccggcccggtgctggggctcctcgggggggggggctcttccgggctgtctccctcc ggggcgggggtttctggccgtgggggtcttgcctggcctccgggctcctgcttgtcttgccttccttctctggtcggttg tggctcggggctccgtgggtccctggcgcccgtttgtgttttgtcttttcccctggcgtccctgtgcccctctcctctcc ttcctctgcttctcgctctcctttgtggggccctccctgctgctcttggttttgggctttttttctcttcctcctttttc gtgcgtgggcctccgcacgcctcttgccacctcctgcgcagggcagcgccttggggccagcgccgctcccggcgcggcca gcagggcagccagcagcgcgcagccgacggccagcatgcttcctcctcggctaccactccatggtcccgcagaggcggac aggcgcbcgcctcttgccbcctcctgcgcbgggcbgcgccttggggccbgcgccgctcccggcgcggccbgcbgggcbgc cbgcbgcgcgcbgccgbcggccbgcbtgcttcctcctcggctbccbctccbtggtcccgcbgbggcggbcbggcgctgcc cggcggggtgtgcgcttggcgctcccgtgctcggttctctgtctcccggtcccccttgcctggcgtctcgggccttcgtc ctcttcctcttcttccttccgctccgtgggggctgcttggtgggggcctgtgcctcggggtcccggggcttctggccctt gccgttcatggtggctaggtggggcgttcbtggtggctbggtggggcggggtgggtbggccgtgtctgggggttggccbt gttggttgcctcttggtggtgcgccgggcgcgtcttggctttcttctccttcgggccctcgggccggtgcttgtgggctc ctcccgggcggcctccccgggcgggggcttcttggcgctggcgggggggcctcctgctctgtggctgggcgttccttggt gttctgggtggtggcgggcgtggtggcctctgtgggggcccgcggctgcbggggttgcctgtctgcttcgtcctttgcgc tcccgggccgccggggtgggtaggccgtgtctgggggttggccatgttggttgccgggcccgcggctgcaggggacaggg gctgtaatcttcatctgcaggtggcatgccagtgaaatttagatcatcaaaatcccacatctgtggatctgtaatatttg acatgtcctcttcagtttcagcaatggtttgatctaactgaagcaccggccaggbcbggggctgtbbtcttcbtctgcbg gtggcbtgccbgtgbbbtttbgbtcbtcbbbbtcccbcbtctgtggbtctgtbbtbtttgbcbtgtcctcttcbgtttcb gcbbtggtttgbtctbbctgbbgcbccggccbggtggctcggtgcttctgcccctgttgttgcggcgctcggttggtgtg gcccctgtggtgcttcgtttccccctctttctctttgttcgggggttcttgtggcgggctgcttgtctcgttccgccctg tcgggcgggaagcctctctcctctccccagatccgcgacaggccgcaggcaagaaccagcgcaaccagggcgcgtccgca cagacttggaggcggctgcatgctgctacctgctccagaagcgtccggtggccgccgcgccctgtcgggcgggbbgcctc tctcctctccccbgbtccgcgbcbggccgcbggcbbgbbccbgcgcbbccbgggcgcgtccgcbcbgbcttggbggcggc tgcbtgctgctbcctgctcgggcgggbbgcctccggtggccgccgcgcgtccggtggccgccgcgcctctctcctctccc cgtggccctgtcgggcgggtcctgccgtcctgtctccttttcttttgctgtcttgtcttcccgtctctgctttgtctgtc ctccccgtctcctcccactgcttctcccgggggcttccccggcttcgggtggccggtgtcccgggctccggcgcggcggc ggcttcggctgcgggtgggtggcgcgggctgccgggtccgcgcggcgcctgggcccttgtgctgctttttgcttgttccg ttctggctgctccggtctgtgttgtggttgttttgtttcttcttgggtgtgggccttgcggttttggctgtgggcccttt ggggccttggcttctggctcgtctgtcctccccgtctcctcccactgcttctcccgggggcttccccggcttcgggtggc cggtgtcccgggctccggcgcggcggcggcttcggctgcgggtgggtggcgcgggctgccgggtccgcgcggcgcctggg cccttgtgctgctttttgcttgttccgttctggctgctccggtctgtgttgtggttgttttgtttcttcttgggtgtggg ccttgcggttttggctgtgggccctttggggccttggcttctggctccatccacatgattgcttagatttgtgctgtatc tctcaggattatcactgattacacatccaaccagtgccagccaaaaggatgccctgaggcaaagggtttccatcttgagg caaatttgaggacbtccbcbtgbttgcttbgbtttgtgctgtbtctctcbggbttbtcbctgbttbcbcbtccbbccbgt gccbgccbbbbggbtgccctgbggcbbbgggtttccbtcttgbggcbbbtttgbggbgggctbbgbtgbtccbcbtcbct bccbcgttgcccbccbcbgbggtcbccbcbbtgbccgtgtbggcbgctgcccbbbggbcbbtttgccbggctggttgcbc gbbctgbttgggttccgbggtgttbgtggbgbtgtttggggbgbggtctgbgtccbccgggbggbcgttbtccbtttcgb bgctbggcggtbbbgccctbctbtctgtbcbcbbcccccctctgcbgcbgbgtcctgtcgtggcgcctggggctcbgggt ccgggctaagatgatccacatcactaccacgttgcccaccacagaggtcaccacaatgaccgtgtaggcagctgcccaaa ggacaatttgccaggctggttgcacgaactgattgggttccgaggtgttagtggagatgtttggggagaggtctgagtcc accgggaggacgttatccatttcgaagctaggcggtaaagccctactatctgtacacaacccccctctgcagcagagtcc tgtcgtggcgcctggggctcagggtccgtcctgtcgtggcgcctggggctcttcttttgtgggctctttggtggctgtgg ctgtggtctctgtggttgctgccctgggtctgggggtgtggccttggggccgtcctctggctcctcctcgtgggcccccg gtgbcbttgbgcbtgtcggcgcggtcccgttbbgbgtgggcccgccagcccagccactccacttgggggcgggtggccag cacgaacagcacccagaggaaggggggcggcccagaagggcagcccgcaggccaggatcaggtctgctgcggccggagat aatggcattcaccacgcggcggcccagcgcacgccgcgcatccggcccgggttctgacctgcagcccccgtctccttggc attcctgggccccagtcactcctctccctgccccccttgctggggcagggacggggtgbcbttgbgcbtgtcggcgcggt cccgttbbgbgtgggcccgccagcccagccactccacttgggggcgggtggccagcacgaacagcacccagaggaagggg ggcggcccagaagggcagcccgcaggccaggatcaggtctgctgcggccggagataatggcattcaccacgcggcggccc agcgcacgccgcgcatccggcccgggttctgacctgcagcccccgtctccttggcattcctgggccccagtcactcctct ccctgccccccttgctggggcagggacggccgtgttgtcbgtggtgctgcccgtttgbggtbtggcgctccbccbbttcc cttttctccttgttttccgtttctcttgccgtctgtggtt (SEQ ID NO: 11778) cttgctcctgggggcctcctggtccctctggctgttcccggccctggbctggggcbggggccgcgtbggcgcggctcgcc bggbcgggcbgcgccbgcbgcbgcbggctcbgcbtcctggccbcggbbttccggtgtgcggggcctggtgcccctgggcc tcgggtgctgcctgtgcgctgccttcttctcctgggtcctcgccggggcccttgctgccctggctgtgccctgggggtct gggttcggctgtccccbgcbggbccbgtcccbtccbcbgcgtgtgbtgbgtbgccbttctcctgcbgccgbggggcgcgg gcgbgcbtcgctttgggcttttctcctttggtttgbgcgccbggbccgcgcbcbgcbgcbgggcgcgggcgbgcbtcgcb gcggcgggcbggggggctcccgccgcgbgbggttbtgggctcccbggbccbcccgcbccgcgcggbcgtttbcbttcgcc bcgcbgtgcgcggccgbcbtgbcgbbgttgggcgcbbtcbgggtggcgccgcbgbbgtggcctccgcgcbgctgcbgggb cbccbtgbbgggccbcgcgtggggccgcgctcgccggccccccbcbbtctccgbggccbgcgcggtgccccccbgcbgcb bggccggcbggbcbcbggcgbggbgbcbcgcgbgtcggcggccgbgggtcbtggtggggctggggctccggggtctctgc ccctccgtgctggtggggctggggctccggggtctctgcccctccgtgccgcgtggggccgcgctcgccggcccccccct gccgggtgggctcccgccgcgcgccggcctgccggcccctcgtgggtcctgctggccgggtccgggtcccgggggtgggg cgcgbgtcggcggccgbgggtcccctccbcbtctgctctgbcctgctggbctctggbtctgbbgbtbcgccbtgtbgggg cgggbgtggggcctgctctcccggcctccgbtgbtctcccctgcctcbgccccbgtgggtbggbgbbbggccbgcbgbbg cbggbgtggctgcbtctttcctggtggggcctgctctcccggcctccgtgtgttgctgggtgttttcccgtctctggtct gccttcgggggtcgtccggggctgcbgcbbcctcbtcbgctcttgcctggbgtggctcbgcctgggcctgcbgggccbcc bggbgbbtggcbgcbbggbtggcgbgggtcctcbtggctggggtcbcbgbtcctctbgctbggcbgggtgbccbgbgbgg gcgggtcctcbtggctgggggcctgggcctgcbgggccgctcttgcctggbgtggctcgcccbgbgtcttccctggtcgc tgcbbtctgctccggggctgcbgcbbcctcbtcbgctcttgcctggbgtggctcbgcctgggcctgcbgggccbccbggb gbbtggcbgcbbggbtggcgbgggtcctcbtggctggggtcbcctggbggbgggbgbgcbgggggtcctcbtggctgggg tccctctctcccgtcctcggtttcctttgcggtcttggcccgggctccgggtgcccgcccgcccgccggccgccgccccg ccgggctgtccccgccccgccccggcccggggcgcgggggcggccctcccgcccctctgggccggcgcgggcgtcggccg ctcgcgcctggggttccctctcctccccctgtgcgcctgcctcttgctcttctgcgtccgctgccttctcccctctcctc ggccgttgcctgtgctgtccgtcctgtcgcccttccgtggtgctgttgtctcttctgccctcggtgtgctggtgctggtg gtggtgcctctgcccgtgctcgccctgcctgggctggcctcttcgggtgtggctttggggctctcttggttgccctttct tctcgtggtgcctctcctccctggcttggtcgttgtctggggtggtgctcctctccctttccctgctggccgtttgtcct gttttctgtcttcctctttcctcctgtttctccgtttggcttgctgcttgcggggctgtctcccttgcccctgtgggctt tccctggtccggtcttctccttgggggtcgcccttcttggtgggctggctcgtctgtctttttccttcctgggggtggcc gttgtgggcggtgtggtccgccttgcctctgctggtctttcctcggtbgbcgcgctcgbbctcgggtgggccggtggtgb gcggcggcgbcbcgcggbbggccctgcgcgccgbgbtcbcctgcbgggbgbbgtbggcttgcbgcbggbctcccbggbgg gtgbcbgcbgccbgtbgbgctbcctcgtccttcbtggtbccgtcggtgtggtggcbcgggctgtgtgtgbbggcgbgctg ggccccgtctgctgctcctcgtgccgcctcgtccttcatggtaccgtcggtgtggtggcctcgggtgggccggtggtggg gcgcgcgcgctcgcgtggctccggctcttctttcccggctccgtcggcccgggggccttggtctccctcgtccttcbtgg tbccgbccggcggbgccgccbgggtggbctgggbgtgggtttctccccgccgttctcbcccbccgcgctgbgctcbgcgc ctbbgbctgctgtttctggbgctccttggcbbgccbcbbbcbgcbgbgbgbbbbtcbtgbgcbbbtbbtccbttctgbbb bbbbgggbtcbbbbbcctcccgttccccgttcgcctggcgcgcgctgcgggttcctcgtgggtttctccccgccgttctc cggtctgttgcctttgtgggcttcttgtctttttggctgttcttttcctgcttggcgtcttttcctttctttgtgctcgg ttgtgggtccgctggtcctttgccctgtgtgtttctgctgcccgttcgcctggcgcgcgctgcgggttcctcgtgggttt ctccccgccgttctccggtctgttgcctttgtgggcttcttgtctttttggctgttcttttcctgcttggcgtcttttcc tttctttgtgctcggttgtgggtccgctggtcctttgccctgtgtgtttctgctgggbgctgbtbctgcbgatttcbgbg ggbbgbbccctgbtbctcbccbgcttcbgctctggbgcbcbbgbgbbbgbgcbgcbgggggbgbggbbgbbgcbgcbtct tcccbgbgbggctgcctgbgcbbbtgctggttttcctttccbgtcttgggttttbtbbctcccbgbbggcbbgbgbgggg cbbggcgttttcttctctcgctggttttcctttcctggcagtgggtgggggtgggggtggggtggcttccttgttcctgg gggtgtcctcttgctctgggcttttctccccttttccttcctgtctgttttcctggggctctcctctgtctctgtgtcct tgccctggccctcttccctctcctgtctcctgtccctgtgttccgcccgtcttccctctcctgacctccttttcctccgc tgggtggggccctgcctgttctctgctccctggcttggggtttcttctgtgtgtcttcttcctctgttggctggctttct ccttcttttgtcttcctgggtgccccttct cct tcttgggtccttggtgcttgggctggggcgtcttggggtgcbggg cccbtcctgctgcgcctgggcgctgctgtgcgtccgtctgctggggggccggggtggctgggccctgcttgccgcacgac cccgggccgacccgaggctcggggggctgtgttctggcgctggtgggcttgggcccctctgggggctgggtttcctgctg cgcctgggcgctggcgtcttggggtgcggggccggggggccggggggccgctgttcgtgggcctgggggtgcctgtggct gccggttgccccggttggtggcgccgtcctgctgccggtcgttggctgggtccccccgcccgtttcctggggtccgcgtg gggtgctccggttcctcgtgccgctgctgccttgtctttccggccgtggcggcgtggtggtccgccccccctggccttct gctcggggtctggctggttgccggtgcccttggcggcggtcttcttcctggtggctctgggcccggccggtctcgggcgt ctcgtgttcgctcttgtgctgttccggccgctccttcctcttccgccgccgccgctccccgcccgctcgtcgccctggcc cggcctcctcctggccgctgtctcgggcggcggccttggcgctccgtttggggctgcctctggcgcttccggccctcggc ctgggcgctctcttccgcctgtgctggtggccctcgtgggcccctcctggcctccggtgtcctgtggtcccccggctggt ggccgggccggttgggcgggcgtgggcgccggcgggtcctccgggctgcccttctccgccgggggtcccgcgctcctgct gttccctgggctcttctgcctctctcctgggtgggtgctgggtgccggggtctccgggcttgccccgcgctgctgggcgt tctgcggtcttggggttgtctgtggccccgctcgtgtcgccctccgtcgcccgtcgccggcctcgtcccctcctgggtgc gcggcgggctggtcctggcgttttgctccttcctgggcgtcttggggtgcbgggcccbtcctgctgcgcctgggcgctgc tgtgcgtccgtctgctggggggccggggtggctgggccctgcttgccgcacgaccccgggccgacccgaggctcgggggg ctgtgttctggcgctggtgggcttgggcccctctgggggctgggtttcctgctgcgcctgggcgctggcgtcttggggtg cggggccggggggccggggggccgctgttcgtgggcctgggggtgcctgtggctgccggttgccccggttggtggcgccg tcctgctgccggtcgttggctgggtccccccgcccgtttcctggggtccgcgtggggtgctccggttcctcgtgccgctg ctgccttgtctttccggccgtggcggcgtggtggtccgccccccctggccttctgctcggggtctggctggttgccggtg cccttggcggcggtcttcttcctggtggctctgggcccggccggtctcgggcgtctcgtgttcgctcttgtgctgttccg gccgctccttcctcttccgccgccgccgctccccgcccgctcgtcgccctggcccggcctcctcctggccgctgtctcgg gcggcggccttggcgctccgtttggggctgcctctggcgcttccggccctcggcctgggcgctctcttccgcctgtgctg gtggccctcgtgggcccctcctggcctccggtgtcctgtggtcccccggctggtggccgggccggttgggcgggcgtggg cgccggcgggtcctccgggctgcccttctccgccgggggtcccgcgctcctgctgttccctgggctcttctgcctctctc ctgggtgggtgctgggtgccggggtctccgggcttgccccgcgctgctgggcgttctgcggtcttggggttgtctgtggc cccgctcgtgtcgccctccgtcgcccgtcgccggcctcgtcccctcctgggtgcgcggcgggctggtcctggcgttttgc tccttcctggctgccccbgtttttgbtcctcbcbtgccgtggggbggbcbbtggctgcctccccggggtttctgctgctt gctgcttctttcccgtctcccttctttcccgtctcctttttgcctctttgggttcctgttgtttctggcctgcttggtgg cggcttgtgcgtttcctctctcttctcttgggtctccgcttctcgtcctgccttttcctgtctctgtcgcgccgttcctc ctccggcgtcctcctgccctgtgctgtttgcctcgggtggtgcgggtcccggtgctcccccggcgggccggctggttgcc tgggcctgtctggtggggtgtggggccgctgggttgggggtgtggtgggctcttctgtggcctgtggggctgttggtgtc tctgtgggcgtgtgctgggtcttggggcttcctcccttgtgctgggtgcggcctccccgccccccttctgggccggtggc ctggctccttgtgggcgcttctggctcttgccctgtccttcttcgcctcgtggctgctgggctgc (SEQ ID NO: 11779) cctccttcctggtctgtctgccbgbcbbbtttgggbbgtgbbcbgttttggbbccbtgtttcccbgtctctgbgctgtgg cgccctgctgctctttctgcttcccttggtgggttgggccgctggttgttctggggttcttgctgccccttctgtccctg tttgctggtgtctgcgcccccbbcbgbbgbbgcbgbcbbbtttgggbbgtgbbcbgttttggbbccbtgtttcctgtgcg ctcggcctggtcccgggggtctcctcttgttgttgcttgcgcctcctgctgggggtccctctgttcttgttttgggggcg ggcccggccgttgtcttggtttgggggtttccgttggggttctcctggcccgggccttgcccggccgtggtcccggcttc gttcctgtctccgtctcggctcttctggggccttgcgctgtctttggtggcbccgtccbgtgbtggtgcggtbcttgtcg ctgcbgcgctcggcctggtcccggbgbgcgcgcgggccgggggctgctgggggttggcccggggtgccccgccgctgggt gccctcgtcctctgcggtcgtgtctcctggctctggttccccgctgcgcccgttgtcctctggggtggccttcgctcccg ggtctggttcttgtgttgggggtccctttttgggcctgttgtggcgtggcttgtgtgttcggtttctgccctgtcctccg gcgtccccggbgcctccccggggcbggbtgbcttttgbgggggbcbcbgbtgtctgggcbttgccbggtcctgggbbcbg bgccccgbgcbggbccbggbgtgcgggcbgcgcgggccgggggctgctgggbgccbtbgcgbggctgbgcctcttttctg tttttcccctctgcctttgtttgggttcgcttcctttctgcttcttccctgtgtctcctgtctccgcttttttcttcgtc tttgttgttttctcttccttgctgbgcbbgbtbtctbgbttctggggtggtctcgbttttbbbbgcttgbgbbgctgcbb bcbttbtccbbbgtbtbtttgbggctccbbggbtcbcgbccbtcttcccbggcbttttbbgttgctgtcgtbbgtgbgbg ctgbgbgbbbctgtgbbgcbbtcbtgbcttcbbgbgttcttttcbcccgttcttggcttcttctgtccgttggcttctcg ttgtccctgtgggcttctcgttgtccccccttcgggggctggtggggccgtccttgcctgctgggttcttggcttcttct gtccgttggcttctcgttgtccctgtgggcttctcgttgtccccccttcgggggctggtggggccgtccttgcctgctgg ttttctctttcgctttcttttcgtctcctgttcctccttttttgctgttttttctccttcttctctcctttcttttcttt tctctttcgctttcttttcgtctcctgttcctccttttttgctgttttttctccttcttctctcctttcttttcctctgt cttgttctggtccttcgtggggctctgtgtcgcgtgggtgcggccgtggccggcggbccbggbgttggbgcbggbgcbgg bcgggcbggcggctcbtgtttggbtcggcbggbggcbctcctctggttggcttccttcgccggcbcbtgctbgcbggbbg bbcbgbgggggbbgcbgttgggbggtgbgbcccbttbbtbggtgtcgbtccctgtttcccccctttcgttctgcgtttgc ctttggcgttttttgtttgttttctctctccgtctttcttctcccctgtgggbbtttctgtggggbtggcbtbcbcgtbg gcbgctccbbgbgctbgcbbbctcbbbtgcbgbbgcbtcctcbtggctctgbbbcggtgggaatttctgtggggbtggca tacacgtaggcagctccaagagctagcaaactcaaatgcagaagcatcctcatggctctgaaacggggggtggcttcctg ccgcgtctctgggccgtcccgtccctcggccccgcgccgcgctcggctcctctccctctggcccggctcggggcggggcg ggg^c99tgggcgggcggcgctgccctgcgcgcggcgctggcccctgctggccgtcggctgcgcgctgctggctgccctgc tggccgcgccggggcctgtccgcctctgcgggcgctgtctcctggcttgtcttccggctcttctgctggggtggggctgg gcggccggcccggtgctggggctcctcgggggggggggctcttccgggctgtctccctccggggcgggggtttctggccg tgggggtcttgcctggcctccgggctcctgcttgtcttgccttccttctctggtcggttgtggctcggggctccgtgggt ccctggcgcccgtttgtgttttgtcttttcccctggcgtccctgtgcccctctcctctccttcctctgcttctcgctctc ctttgtggggccctccctgctgctcttggttttgggctttttttctcttcctcctttttcgtgcgtgggcctccgcacgc ctcttgccacctcctgcgcagggcagcgccttggggccagcgccgctcccggcgcggccagcagggcagccagcagcgcg cagccgacggccagcatgcttcctcctcggctaccactccatggtcccgcagaggcggacaggcgcbcgcctcttgccbc ctcctgcgcbgggcbgcgccttggggccbgcgccgctcccggcgcggccbgcbgggcbgccbgcbgcgcgcbgccgbcgg ccbgcbtgcttcctcctcggctbccbctccbtggtcccgcbgbggcggbcbggcggggtggbbbggtttggbgtbtgtct ttbtgcbctgbcbtctbbgttctttbgcbctccttggcbbbbctgcbccttcbcbcbgbgctgcbgbbbtcbggbbggct gccbbgbgbgccbcggccbgcttggbbgtcbtgtttbcbcbcbgtgbgbtggttccttccgggcttgtgtgctctgctgt ctcttggttccttccggtggtttcttcctggctcttgtcctttctcttggcccttggccgggbgtgggggtcctggbcgg cbctgbbggcbtccbgggctcccttccbgtccttcttgtccgctgccbgcbccccttcbttccbgbggctgbtggcctcc bccbgggbcbtgbttbggtbgbbbctbggbggccggcctccbccbgggbcbtggtccttcttgtccgctgcctctctggg gttttcggtctgggtgggctttcctcctggggctgctgctgggctcttctttttgtttctggcctggtgctctctcgtgc cctttcccttgggtgtcttgtttttgtggcctccbccbgggbcbtggtctttgtttctgggctcgtgccccbtcccggct tctctctggttccgtcctctgtggtgtttggccctgcttccttttgcctgttgagggggcagcagttgggccccaaaggc cctctcgttcaccttctggcacggagttgcatccccatagtcaaactctgtggtcgtgtcatagtcctctgtggtgtttg gagtttccatcccggcttctctctggttccaagggagbgggggcbgcbgttgggccccbbbggccctctcgttcbccttc tggcbcggbgttgcbtccccbtbgtcbbbctctgtggtcgtgtcbtbgtcctctgtggtgtttggbgtttccbtcccggc ttctctctggttccbbgggbgggcbcggggcbgtgggcgggcbbtgtbggcbbbgcbgcbgggtgtggtgtccgbggbbt btggggbggcbgbtgcbggbgcgcbgbgggcbgtbgcbbtgbggbtgbcbgcgbggcgtgccgcggbgbccttcbtggtb cctgtggbgbggctgtcggbgggggtgtggtgtccgcttggcggttctttcgggtgtttcttctctgggttggcctgctg ctcgtcgtggtcgctccgctcccgggttcgtctcgctctgtcgccccttccttccttgtcgtgttcctcccttccttgcc tctgbtgtttgttbccbbbgcbtcbbgbbtbgctttgctbtctbbggbtcbcbtttbgbcbtbggbbbbcgctgtbggtc bgbbbgbtgtgcttbccttcbcbcbgbgctgcbgbbbtcbggbbggctgccbbgbgbgccbcggccbgcttggbgtcbtg tttbcbcbcbgtgbggtgctccggtggctttttgcttgtgtgctctgctgtctctgttccttccggtggtttcttcctgg ctcttgtcctttctcttggcccttggccccttgbgcbggbbgctctggggcbgggbgctggcbgggcccbggggggtggc ttcctgcbctgtccbgbgtgcbctgtgccbcbgcbgcbgctgcbgggccbtcbgcttcbtggggctctgggtggcbggtc cbgccbtgggtctgggtggggctgggctgcbggctccgggcggtccbgccbtgggtctgggggctgggctgcbggctccg ggcgggcgggtgcgggctgcgtgctgggggctgccccgcaggccctgcggtccbgccbtgggtctgggggctgggctgcb ggctccgggcgggcgggtgcgggctgcgtgctgggggctgccccgcaggccctgcgcbccgcctggbgccctggggcccc cctgtcttcttggggbgcgcctcctcggccbgctccbcgtcccggbtcbtgctttcbgtgctcbtggtgtcctttccbgg ggbgbgbggggctggtcctctgctgtccttgctggtgctcbtggtgtcctttccgccctggggcccccctgtcttcttgg ggcctcttccctctgggggccgtctctctccctctcttgcgtctctctctttctctctctctcttcccctttcccgctct ttctgtctcggtgtctggttttctctctccgctggctgcctgtctggcctgcgctcttggcctgtgctgttcctcctccg gttcctgtcctctctgtctgtcgccccctctggggtctccctctgggtggtggtcttgttgcttgggctgggctccgtgt ctccbgtgctcbtggtgtccgctgbgggbgcgtctgctggcgctggtcctctgctgtccttgctggtgctcbtggtgtcc tttccgccctggggcccccctgtcttcttggggcctcttccctctgggggccgtctctctccctctcttgcgtctctctc tttctctctctctcttcccctttcccgctctttctgtctcggtgtctggttttctctctccgctggctgcctgtctggcc tgcgctcttggcctgtgctgttcctcctccggttcctgtcctctctgtctgtcgccccctctggggtctccctctggcgt ggtggtcttgttgcttgggctgggctccgtgtctccbgtgctcbtggtgtccgctgbgggbgcgtctgctggcctgctgb ggcttgggtctccgggcgbttctctgcbgbbgbtgctcbbbgggctccggcbgttcctccttgbtctggtcgctgtcgtb ccbgtcggbccbgtbbttcbgbtcbtcbttggctcctbtttcttctgcbbbcbgctgbgtggbgbcbbgbbbbbbgbctg ccbbggccbcgbggbttttcbtgttggbttttgcgbcggbcbgtcccgcggggtgctgagtttctctggttcctccgbgc gcbcgtggtcgctccgcgtttctctggttcctccggtcccgcggggtgctgtctggtcgctgtcgtggcttgggtctccg ggcggtttccttccttttccgccggcccttctcactggaggcaccgggcagtcctccatgggagggttgggcttggccgg ggctgcccggtgcctcctcttggctggtccctcgttgtccttgggccccgctcccgctgctcggcctccgtgttctttgg cctcttgctccgcctgctgtcttgtcccgtcccctcctcgcttgcgtttccctcttccttgtcttccaggccttcctccg cttccgctgctggggcccgcgccgggggggcgctcggctccgcggcttcctccccggctggggggtcctggtctccgggg cctgcggctcgcgggctcggggctgcgtgcgccgcgcgcggcgtccgcggtgggtggcgctgtcccgccgtggtgtgtct ccgttctcgtcctgcgccgtcctggtctgcccgtggggtcctgggcgtggtggggggcgtctggtgcctcgtctgccccg tggggcttcgggctcggggctgttcgtcccccctgccgctctgtggcctccggggctcctcgttttcgctgcttcgggtg tccttctcggcgtgtggccccgggtcccggccctgctgggctgggcggggtcgctgccctgggcttctggcccgtctggt tgtctgtcggtgcttgtctcgggtttctggcctctgtgctgggcgcttctctgcctcctgctccgccctcctggtggctc ggctgggggtgcccgtgcgggggtgggtgtggggtgttttcggggtcctccccttcccgtttca cttggctttatcctc tccccttgttcctcccctctcctgctctggrgtctcctcttccctccctcccctgccgtgttgtctgtgggtgtcgtttc gctcttgttgccctgggcccttccctgctgggggggagtttcatcttgggtttcbtcttggctttbtcctctccccttgt tcctcccctctcctgctctggrgtctcctcttccctccctcccctgccgtgttgtctgtgggtgtcgtttcgctcttgtt gccctgggcccttccctgctgggggggbgtttcbtcttgggggggbgtttcbtcttggctttccgtgttgtcbgtggtgc tgcccgtttgbggtbtggcgctccbccbbttcccttttctccttgttttccgtttctcttgccgtctgtggtt (SEQ ID NO:11780) atgccgccctccatctcagctttcσaggccgcctacatcggcatcgaggtgctcatcgccctggtctctgtgcccgggaa cgtgctggtgatctgggcggtgaaggtgaaccaggcgctgcgggatgccaccttctgcttcatcgtctcgctggcggtgg ctgatgtggccgtgggtgccctggtca ccccctcgccatcc cat aacattgggccacagacctacttccacacctgc ctcatggttgcctgtccggtcctcatcctcacccagagctccatcctggccctgctggcaattgctgtggaccgctacct ccgggtcaagatccctctccggtacaagatggtggtgaccccccggagggcggcggtggccatagccggctgctggatcc tctccttcgtggtgggactgacccctatgtttggctggaacaatctgagtgcggtggagcgggcctgggcagccaacggc agcatgggggagcccgtgatcaagtgcgagttcgagaaggtcatcagcatggagtacatggtctacttcaac tct tgt gtgggtgctgcccccgcttctcctcatggtcctcatctacctggaggtcttctacctaatccgcaagcagctcaacaaga aggtgtcggcctcctccggcgacccgcagaagtactatgggaaggagctgaagatcgccaagtcgctggccctcatcctc ttcctctttgccctcagctggctgcctttgcacatcctcaactgcatcaccctcttctgcccgtcctgccacaagcccag catccttacctacattgccatcttcctcacgcacggcaactcggccatgaaccccattgtctatgccttccgcatccaga agttccgcgtcaccttccttaagatttggaatgaccatttccgctgccagcctgcacctcccattgacgaggatctccca gaagagaggcctgatgactag (SEQ ID NO: 11789) atgccgccctccatctcagctttccaggccgcctacatcggcatcgaggtgctcatcgccctggtctctgtgcccgggaa cgtgctggtgatctgggcggtgaaggtgaaccaggcgctgcgggatgccaccttctgcttatcgtctcgctggcggtggc tgatgtggccgtgggtgccctggtcatccccctcgccatcctcatcaacattgggccacagacctacttccacacctgcc tcatggttgcctgtccggtcctcatcctcacccagagctccatcctggccctgctggcaattgctgtggaccgctacctc cgggtcaagatccctctccggtacaagatggtggtgaccccccggagggcggcggtggccatagccggctgctggatcct ctccttcgtggtgggactgcccctatgtttggctggaacaatctgagtgcggtggagcgggcctgggcagccaacggcag catgggggagcccgtgatcaagtgcgagttcgagaaggtcatcagcatggagtacatggtctacttcaacttctttgtgt gggtgctgcccccgcttctcctcatggtcctcatctacctggaggtcttctacctaatccgcaagcagctcaacaagaag gtgtcggcctcctccggcgacccgcagaagtactatgggaaggagctgaagatcgccaagtcgctggccctcatcctctt cctctttgccctcagctggctgcctttgcacatcctcaactgcatcaccctcttctgcccgtcctgccacaagcccagca tccttacctacattgccatcttcctcacgcacggcaactcggccatgaaccccattgtctatgccttccgcatccagaag ttccgcgtcaccttccttaagatttggaatgaccatttccgctgccagcctgcacctcccattgacgaggatctcccaga agagaggcctgatgactagatgagtgtcagaagtgtgaagggtgcctgttctgaatcccagagcctcctctccctctgtg aggctggcaggtgaggaagggtttaacctcactggaaggaatccctggagctagcggctgctgaaggcgtcgaggtgtgg gggcacttggacagaacagtcaggcagccgggagctctgccagctttggtgaccttgggccgggctgggagcgctgcggc gggagccggaggactatgagctgccgcgcgttgtccagagcccagcccagccctacgcgcgcggcccggagctctgttcc ctggaactttgggcactgcctctgggacccctgccggccagcaggcaggatggtgcttgcctcgtgccccttggtgcccg tctgctgatgtgcccagcctgtgcccgccatgccgccctccatctcagctttccaggccgcctacatcggcatcgaggtg ctcatcgccctggtctctgtgcccgggaacgtgctggtgatctgggcggtgaaggtgaaccaggcgctgcgggatgccac cttctgcttcatcgtgtcgctggcggtggctgatgtggccgtgggtgccctggtcatccccctcgccatcctcatcaaca ttgggccacagacctacttccacacctgcctcatggttgcctgtccggtcctcatcctcacccagagctccatcctggcc ctgctggcaattgctgtggaccgctacctccgggtcaagatccctctccggtacaagatggtggtgaccccccggagggc ggcggtggccatagccggctgctggatcctctccttcgtggtgggactgacccctatgtttggctggaacaatctgagtg cggtggagcgggcctgggcagccaacggcagcatgggggagcccgtgatcaagtgcgagttcgagaaggtcatcagcatg gagtacatggtctacttcaacttctttgtgtgggtgctgcccccgcttctcctcatggtcctcatctacctggaggtctt ctacctaatccgcaagcagctcaacaagaaggtgtcggcctcctccggcgacccgcagaagtactatgggaaggagctga agatcgccaagtcgctggccctcatcctcttcctctttgccctcagctggctgcctttgcacatcctcaactgcatcacc ctcttctgcccgtcctgccacaagcccagcatccttacctacattgccatcttcctcacgcacggcaactcggccatgaa ccccattgtctatgccttccgcatccagaagttccgcgtcaccttccttaagatttggaatgaccatttccgctgccagc ctgcacctcccattgacgaggatctcccagaagagaggcctgatgactagaccccgccttccgctcccaccagcccacat ccagtggggtctcagtccagtcctcacatgcccgctgtcccaggggtctccctgagcctgccccagctgggctgttggct gggggcatgggggaggctctgaagagatacccacagagtgtggtccctccactaggagttaactaccctacacctctggg ccctgcaggaggcctgggagggcaagggtcctacggagggaccaggtgtctagaggcaacagtgttctgagcccccacct gcctgaccatcccatgagcagtccagcgcttcagggctgggcaggtcctggggaggctgagactgcagaggagccacctg ggctgggagaaggtgcttgggcttctgcggtgaggcaggggagtctgcttgtcttagatgttggtggtgcagccccagga ccaagcttaaggagaggagagcatctgctctgagacggatggaaggagagaggttgaggatgcactggcctgttctgtag gagagactggccagaggcagctaaggggcaggaatcaaggagcctccgttcccacctctgaggactctggaccccaggcc ataccaggtgctagggtgcctgctctccttgccctgggccagcccaggattgtacgtgggagaggcagaaagggtaggtt cagtaatcatttctgatgatttgctggagtgctggctccacgccctggggagtgagcttggtgcggtaggtgctggcctc aaacagccacgaggtggtagctctgagccctccttcttgccctgagctttccggggaggagcctggagtgtaattacctg tcatctgggccaccagctccactggcccccgttgccgggcctggactgtcctaggtgaccccatctctgctgcttctggg cctgatggagaggagaacactagacatgccaactcgggagcattctgcctgcctgggaacggggtggacgagggagtgtc tgtaaggactcagtgttgactgtaggcgcccctggggtgggtttagcaggctgcagcaggcagaggaggagtacccccct gagagcatgtgggggaaggccttgctgtcatgtgaatccctcaatacccctagt tctggctgggttttcaggggctttg gaagctctgttgcaggtgtccgggggtctaggactttagggatctgggatctggggaaggaccaacccatgccctgccaa gcctggagcccctgtgttggggggcaaggtgggggagcctggagcccctgtgtgggagggcgaggcgggggagcctggag cccctgtgtgggagggcgaggcgggggatcctggagcccctgtgtcggggggcgagggaggggaggtggccgtcggttga ccttctgaacatgagtgtcaactccaggacttgcttccaagcccttccctctgttggaaattgggtgtgccctggctccc aagggaggcccatgtgactaataaaaaactgtgaaccctcgcatttgtgttttaataaaagaatctggaagataaatagt cttgaagagagacaaaggaaggaaaatttaaatccttagattcaagcagaagaattccatgtggaaggtttgggttgttg ttgttgttgtttggtgtgttttttgtttttttgtttttttgtttttttttgagatggagtctcgctgtgttaccgggagc gacagagccgcacggccgagtcgagtcccagccagctaccatccctctggagcttaccggccggccttggcttccccagg aatccctggagctagcggctgctgaaggcgtcgaggtgtgggggcacttggacagaacagtcaggcagccgggagctctg ccagctttggtgaccttgggtgcttgcctcgtgccccttggtgcccgtctgctgatgtgcccagcctgtgcccgccatgc cgccctccatctcagctttccaggccgcctacatcggcatcgaggtgctcatcgccctggtctctgtgcccgggaacgtg ctggtgatctgggcggtgaaggtgaaccaggcgctgcgggatgccaccttctgcttcatcgtgtcgctggcggtggctga tgtggccgtgggtgccctggtcatccccctcgccatcctcatcaacattgggccacagacctacttccacacctgcctca tggttgcctgtccggtcctcatcctcacccagagctccatcctggccctgctggcaattgctgtggaccgctacctccgg gtcaagatccctctccggtacaagatggtggtgaccccccggagggcggcggtggccatagccggctgctggatcctctc cttcgtggtgggactgacccctatgtttggctggaacaatctgagtgcggtggagcgggcctgggcagccaacggcagca tgggggagcccgtgatcaagtgcgagttcgagaaggtcatcagcatggagtacatggtctact caacttctttgtgtgg gtgctgcccccgcttctcctcatggtcc catctacctggaggtcttctacctaatccgcaagcagctcaacaagaaggt gtcggcctcctccggcgacccgcagaagtactatgggaaggagctgaagatcgccaagtcgctggccctcatcctcttcc tctttgccctcagctggctgcctttgcacatcctcaactgcatcaccctcttctgcccgtcctgccacaagcccagcatc cttacctacattgccatcttcctcacgcacggcaactcggccatgaaccccattgtctatgccttccgcatccagaagtt ccgcgtcaccttccttaagatttggaatgaccatttccgctgccagcctgcacctcccattgacgaggatctcccagaag agaggcctgatgactagaccccgccttccgctcccaccgcccacatccagtggggtctcagtccagtcctcacatgcccg ctgtcccaggggtctccctgagcctgccccagctgggctgttggctgggggcatgggggaggctctgaagagatacccac agagtgtggtccctccactaggagttaactaccctacacctctgggccctgcaggaggcctgggagggcaagggtcctac ggagggaccaggtgtctagaggcaacagtgttctgagcccccacctgcctgaccatcccatgagcagtccagagcttcag ggctgggcaggtcctggggaggctgagactgcagaggagccacctgggctgggagaaggtgcttgggcttctgcggtgag gcaggggagtctgcttgtcttagatgttggtggtgcagccccaggaccaagcttaaggagaggagagcatctgctctgag acggatggaaggagagaggttgaggatgcactggcctgttctgtaggagagactggccagagatggagggcggcatggcg gggcgggtcgccggggcgggcbcbggcggcgggcbcgcggcctggggbgggcggcgbtggbgggggctgggcgcggcctg gaaagctgagatggagggcggcatggcgggcacaggctgggc (SEQ ID NO: 11792) gaattcccagatgggcagaggtggctgggctggtgaccctaagtgtgtctcctgcctttattctctctagtgggttattc tttcatgtggtatcttgcctacagcatgctgtgtttggacacaaacccctttccttggtttctctgacccagctgagatg gactgattccaaaagaactcacctatgtactggggtaggggagggagggttttttgcagtatttaactaaggttcaaaga gtgctatatagtgagaaaggcttcttttttttttttttttttttttggcagagtgctgcctcctagaaatttctcttggt aacttccttctctgaagcacagataaagaaaacaattacagtagaaacatttatgagggacacattggaggccgatgaag cttttcaagttccagcagtgcagggatgtgggcagaactgacattggaaaatactagaatgatggaaattcagttggaga ggactgccctttttaatgtctggggagtctgctcagggagaaatgacaagtctggcggggacaagtatgggatttggtaa gacttggatcaacttgggatacagggtgggggtcgggagtggaatcaatgaatgatgccagagcagatcaactaacaaga ggaccctgatgagccccaggcagaggcgtctcccttatgccccactctgaagtgtttgttagtaaacaccagaacgccat tgttgttactgctgaattttattttgggctgtacatatttagatgcttaaggtaaaaatgataaagccctcaagccactg tgtgggtttgggtccaagtgttccttcttgctgcctctctaacacgcctggttaaaataatccctttggatggtgctgag aagcacctgaaccaagtgggtccccaaataacaatggcgtgcaagtgtctggttcccagaagttggtgactaggtaagca gcttcagggagagggggctgattcccagacagtcgcctgttcctgcggggatggggctgaggcttggggaatgtgggcag gaggatatgccatttgattctgttgcacacgttcttttcccttctttctgtatgtctggtcattctgctattctgtcgtt cctcacataggttggacattggccggctgccagcataagtgccagtgtgattttgctaggtgtgagctgagaaagagagg tggaggctaagcaggtgtgatgcttctcagaggtgctgagtttttgcccttctgagcagggaatctttgcttatcccttt gaccaaggatctttgctgcaaaggctgggtatcggctgtgctcagcaaagcgtcaactcgtgcaagaacttagcaggaat agttctggctaaggttaggaggctgccaccaaagtctcttttttgttcctctgcttctcccgtttgcctccttatcatga gatctttttgctaagctggcagaaagattgcatagtcagtgcttccagctctgctcccacctgatcctgcactgtcctct ggtccctgaatgaatgaactctgatacccaatcttgtctcgagccttctctatgccactcatggctcctcttctgctctt tccatctttttgctgagagttctgagctctgtacttcctcttggcccatctcacttcctgaaacacccctgaagagggtt gcttatcttgatggaactcaaaaagccaaaaagctgcaggcagaggcgttgaggacatctgtttggggaactaagagcag cagcactttcagattcagtccatatagagctgtcctacagcattctggaaacttgaggatgtgcggtgcataaaggggct ggaagtgacccacctgtgatgagccctttctaaggagaagggtttccaagagatcaccccaccagaaaagggtaggaatg agcaagttgggaattttagactgtcactgcacatggacctctgggaagacgtctggcgagagctaggcccactggcccta cagacggatcttgctggctcacctgtccctgtggaggttcccctgggaaggcaagatgcccaacaacagcactgctctgt cattggccaatgttacctacatcaccatggaaattttcattggactctgcgccatagtgggcaacgtgctggtcatctgc gtggtcaagctgaaccccagcctgcagaccaccaccttctatttcattgtctctctagccctggctgacattgctgttgg ggtgctggtcatgcctttggccattgttgtcagcctgggcatcacaatccacttctacagctgcctttttatgacttgcc tactgcttatctttacccacgcctccatcatgtccttgctggccatcgctgtggaccgatacttgcgggtcaagcttacc gtcaggtagcctgcggcgtggggtgggcagcaattgaggcagctgggaaatgaggctacaaagccagagc

(SEQ ID NO:11795) gccgccgccgccaagatggcggacctggaggcggtgctggccgacgtgagctacctgatggccatggagaagagcaaggc cacgccggccgcgcgcgccagcaagaagatactgctgcccgagcccagcatccgcagtgtcatgcagaagtacctggagg accggggcgaggtgacctttgagaagatcttttcccagaagctggggtacctgctcttccgagacttctgcctgaaccac ctggaggaggccaggcccttggtggaattctatgaggagatcaagaagtacgagaagctggagacggaggaggagcgtgt ggcccgcagccgggagatcttcgactcatacatcatgaaggagctgctggcctgctcgcatcccttctcgaagagtgcca ctgagcatgtccaaggccacctggggaagaagcaggtgcctccggatctcttccagccatacatcgaagagatttgtcaa aacctccgaggggacgtgttccagaaattcattgagagcgataagttcacacggttttgccagtggaagaatgtggagct caacatccacctgaccatgaatgacttcagcgtgcatcgcatcattgggcgcgggggctttggcgaggtctatgggtgcc ggaaggctgacacaggcaagatgtacgccatgaagtgcctggacaaaaagcgcatcaagatgaagcagggggagaccctg gccctgaacgagcgcatcatgctctcgctcgtcagcactggggactgcccattcattgtctgcatgtcatacgcgttcca cacgccagacaagctcagcttcatcctggacctcatgaacggtggggacctgcactaccacctctcccagcacggggtct tctcagaggctgacatgcgcttctatgcggccgaga catcctgggcctggagcacatgcacaaccgcttcgtggtctac cgggacctgaagccagccaacatccttctggacgagcatggccacgtgcggatctcggacctgggcctggcctgtgactt ctccaagaagaagccccatgccagcgtgggcacccacgggtacatggctccggaggtcctgcagaagggcgtggcctacg acagcagtgccgactggttctctctggggtgcatgctcttcaagttgctgcgggggcacagccccttccggcagcacaag accaaagacaagcatgagatcgaccgcatgacgctgacgatggccgtggagctgcccgactccttctcccctgaactacg ctccctgctggaggggttgctgcagagggatgtcaaccggagattgggctgcctgggccgaggggctcaggaggtgaaag agagcccctttttccgctccctggactggcagatggtcttcttgcagaagtaccctcccccgctgatccccccacgaggg gaggtgaacgcggccgacgccttcgacattggctccttcgatgaggaggacacaaaaggaatcaagttactggacagtga tcaggagctctaccgcaacttccccctcaccatctcggagcggtggcagcaggaggtggcagagactgtcttcgacacca tcaacgctgagacagaccggctggaggctcgcaagaaagccaagaacaagcagctgggccatgaggaagactacgccctg ggcaaggactgcatcatgcatggctacatgtccaagatgggcaaccccttcctgacccagtggcagcggcggtacttcta cctgttccccaaccgcctcgagtggcggggcgagggcgaggccccgcagagcctgctgaccatggaggagatccagtcgg tggaggagacgcagatcaaggagcgcaagtgcctgctcctcaagatccgcggtgggaaacagttcattttgcagtgcgat agcgaccctgagctggtgcagtggaagaaggagctgcgcgacgcctaccgcgaggcccagcagctggtgcagcgggtgcc caagatgaagaacaagccgcgctcgcccgtggtggagctgagcaaggtgccgctggtccagcgcggcagtgccaacggcc tctgacccgcccacccgcct (SEQ ID NO: 11809) gccaccatggaaaccctttgcctcagggcatccttttggctggcactggttggatgtgtaatcagtgataatcctgagag atacagcacaaatctaagcaatcatgtggatgatttcaccacttttcgtggcacagagctcagcttcctggttaccactc atcaacccactaatttggtcctacccagcaatggctcaatgcacaactattgcccacagcagactaaaattacttcagct ttcaaatacattaacactgtgatatcttgtactattttcatcgtgggaatggtggggaatgcaactctgctcaggatcat ttaccagaacaaatgtatgaggaatggccccaacgcgctgatagccagtcttgcccttggagacct atctatgtggtca ttgatctccctatcaatgtatttaagctgctggctgggcgctggccttttgatcacaatgactttggcgtatttctttgc aagctgttcccctttttgcagaagtcctcggtggggatcaccgtcctcaacctctgcgctcttagtgttgacaggtacag agcagttgcctcctggagtcgtgttcagggaattgggattcctttggtaactgccattgaaattgcctccatctggatcc tgtccttta cctggccattcctgaagcgattggcttcgtcatggtaccctttgaatataggggtggacagcataaaacc tgtatgctcaatgccacatcaaaattcatggagttctaccaagatgtaaaggactggtggctcttcgggttctatttctg tatgcccttggtgtgcactgcgatcttctacaccctcatgactggtgagatgttgaacagaaggaatggcagcttgagaa ttgccctcagtgaacatcttaagcagcgtcgagaagtggcaaaaacagttttctgcttggttgtaatttttgctctttgc tggttccctcttcatttaagccgtatattgaagaaaactgtgtataacgagatggacaagaaccgatgtgaattacttag tttcttactgctcatggattacatcggtattaacttggcaaccatgaattcatgtataaaccccatagctctgtattttg tgagcaagaaatttaaaaattgtttccagtcatgcctctgctgctgctgttaccagtccaaaagtctgatgacctcggtc cccatgaacggaacaagcatccagtggaagaaccacgatcaaaacaaccacaacacagaccggagcagccataaggacag catgaactgaccacccttagaagcactcct (SEQ ID NO: 11838) taccagtccaaaagtctgatgacctcggtccccatgaacggaacaagcatccagtggaagaaccacgatcaaaacaacca caacacagaccggagcagccataaggacagcatgaactgaccacccttagaagcactcctgaattcgggaaaaagtgaag gtgtaaaagcagcacaagtgcaataagagatatttcctcaaatttgcctcaagatggaaaccctttgcctcagggcatcc ttttggctggcactggttggatgtgtaatcagtgataatcctgagagatacagcacaaatctaagcaatcatgtggatga tttcaccacttttcgtggcacagagctcagcttcctggttaccactcatcaacccactaatttggtcctacccagcaatg gctcaatgcacaactattgcccacagcagactaaaattacttcagctttcaaatacattaacactgtgatatcttgtact attttcatcgtgggaatggtggggaatgcaactctgctcaggatcatttaccagaacaaatgtatgaggaatggccccaa cgcgctgatagccagtcttgcccttggagaccttatctatgtggtcattgatctccctatcaatgtatttaagctgctgg ctgggcgctggccttttgatcacaatgactttggcgtatttctttgcaagctgttcccctttttgcagaagtcctcggtg gggatcaccgtcctcaacctctgcgctcttagtgttgacaggtacagagcagttgcctcctggagtcgtgttcagggaat tgggattcctttggtaactgccattgaaattgtctccatctggatcctgtcctttatcctggccattcctgaagcgattg gcttcgtcatggtaccctttgaatataggggtgaacagcataaaacctgtatgctcaatgccacatcaaaattcatggag ttctaccaagatgtaaaggactggtggctcttcgggttctatttctgtatgcccttggtgtgcactgcgatcttctacac cctcatgacttgtgagatgttgaacagaaggaatggcagcttgagaattgccctcagtgaacatcttaagcagcgtcgag aagtggcaaaaacagttttctgcttggttgtaatttttgctctttgctggttccctcttcatttaagccgtatattgaag aaaactgtgtataacgagatggacaagaaccgatgtgaattacttagtttcttactgctcatggattacatcggtattaa cttggcaaccatgaattcatgtataaaccccatagctctgtattttgtgagcaagaaatttaaaaattgtttccagtcat gcctctgctgctgctgttaccagtccaaaagtctgatgacctcggtccccatgaacggaacaagcatccagtggaagaac cacgatcaaaacaaccacaacacagaccggagcagccataaggacagcatgaactgaccacccttagaagcactcctcgg tactcccataatcctctcggagaaaaaaatcacaaggcaactgtgagtccgggaatctcttctctgatccttcttcctta at cactcccacacccaagaagaaatgctttccaaaaccgcaagggtagactggtttatccacccacaacatctacgaat cgtacttctttaattgatctaatttacatattctgcgtgttgtattcagcactaaaaaatggtgggagctgggggagaat gaagactgttaaatgaaaccagaaggatatttactacttttgcatgaaaatagagctttcaagtacatggctagctttta tggcagttctggtgaatgttcaatgggaactggtcaccatgaaactttagagattaacgacaagattttctacttttttt aagtgatttttttgtccttcagccaaacacaatatgggctcaagtcacttt atttgaaatgtcatttggtgccagtatc ccgaattc (SEQ ID NO: 11840) agtcttttgccctagaaggtataaacaaattggcacctgtggtctccctggaacaaaatgctgcaaaaagccatgaggag gccaagaagctgctgtggctgatgcggattcagaaagggctccctcatcagagacgtgcgacatgtaaaccaaattaaac tatggtgtccaaagatacgcaatctt atcctagtaattgtggtcattgggtgatgttggtttgggcaggccatctctaa tatccttgaaacacctttttctgctctccaggaaggggtcagggctgccacagcggggcttggagtgctttccagggtca caggcatctgtattctttggattccttgaccttccccatttattcccggcattttcctaaaacgtgtgctttgctcctcc tgcatcctccccttgcatgccctcacctaccccacatcttccctaaaaaaagcaagcccaactcaaagaccagttccctc atggaatcatagtggatctgccaagggaggggatgcccagtcctctgttcttcacaagactcccttcttctggctaaggt ttcttatgcaattat (SEQ ID NO:11842) ggccggagccgagccggggtcgggcagcagcagggaccccccagaggcggggcctgtgggaccgctatgggcgtggagat cgagaccatctcccccggagacggaaggacattccccaagaagggccaaacgtgtgtggtgcactacacaggaatgctcc aaaatgggaagaagtttgattcatccagagacagaaacaaacctttcaagttcagaattggcaaacaggaagtcatcaaa ggttttgaagagggtgcagcccagatgagcttggggcagagggcgaagctgacctgcacccctgatgtggcatatggagc cacgggccaccccggtgtcatccctcccaatgccaccctcatctttgacgtggagctgctcaacttagagtgaaggcagg aaggaactcaaggtggctggagatggctgctgctcaccctcctagcctgctctgccactgggacggctcctgcttttggg gctcttgatcagtgtgctaacctcactgcctcatggcatcatccattctctctgcccaagttgctctgtatgtgttcgtc agtgttcatgcgaattcttgcttgaggaaacttcggttgcagattgaagcatttcaggttgtgcattttgtgtgatgcat gtagtagcctttcctgatgacagaacacagatctcttgttcgcacaatctacactgccttaccttcacttaaaccacaca cacaaggtgctcagacatgaaatgtacatggcgtaccgtacacagagggacttgagccagttacctttgctgtcactttc tctcttataaattctgttagctgctcacttaaacaatgtcctctttgagaaaatgtaaaataaaggctctgtgcttgaca (SEQ ID NO: 11865) catatgtatgggaatactgtatttcaggcattataaggaatgaaattataggccgggcattgtggctaacccttgtaatc ctagcactttgagaggctgaagtgggcagatcacttgagcttcagagttcgagaccagcatggacaacatggtgaaaccc agtctctaccaaaaacacaaaaatattagctgggtgtggtggtgcatgcctgtagtcccagctactcaggaggctgaggt gggaggatcgcttgagcctgggaggcagaagttgcaatgagcagagatcgtgccactccgctccagtcttggtgacagaa tgagactccatctcaaaaataaataaataaataaataaaataaatgaaatgaaattataagaaattaccactttttcatg taagaagtgatcatttccattataagggaaggaatttaatcctacctgccattccaccaaagcttacctagtgctaaagg atgaggtgttagtaagaccaacatctcagaggcctctctgtgccaatagccttccttcctttcccttccaaaaacctcaa gtgactagttcagaggcctgtctggaataatggcatcatctaatatcactggccttctggaacctgggcatttt^'ccagtg tgttccatactgtcaatattcccccagcttcctggactcctgtcacaagctggaaaagtgagaggatggacagggattaa ccagagagctccctgctgaggaaaaaatctcccagatgctgaaagtgaggccatgtggcttggccaaataaaacctggct ccgtggtgcctctgtcttagcagccaccctgctgatgaactgccaccttggacttgggaccagaaagaggtgggttgggt gaagaggcaccacacagagtgatgtaacagcaagatcaggtcacccacaggccctggcagtcacagtcataaattagcta actgtacacaagctggggacactccctttggaaaccaaaaaaaaaaaaaaaaaaaagagacctttatgcaaaaacaactc tctggatggcatggggtgagtataaa ac cttggctgccagtgtgttea aactttgtagcgagtcgaaaactgaggc tccggccgcagagaactcagcctcattcctgctttaaaatctctcggccacctttgatgaggggactgggcagttctaga cagtcccgaagttctcaaggcacaggtctcttcctggtttgactgtccttaccccggggaggcagtgcagccagctgcaa ggtgagttgccctgctttaaaatctctcggccacctttgatgaggggactgggcagttctagacagtcccgaagttctca aggcacaggtctcttcctggtttgactgtccttaccccggggaggcagtgcagccagctgcaagccccacagtgaagaac atctgagctcaaatccagataagtgacataagtgacctgctttgtaaagccatagagatggcctgtccttggaaatttct gt caagaccaaattccaccagtatgcaatgaatggggaaaaagacatcaacaacaatgtggagaaagccccctgtgcca cctccagtccagtgacacaggatgaccttcagtatcacaacctcagcaagcagcagaatgagtccccgcagcccctcgtg gagacgggaaagaagtctccagaatctctggtcaagctggatgcaaccccattgtcctccccacggcatgtgaggatcaa aaactggggcagcgggatgactttccaagacacacttcaccataaggccaaagggattttaacttgcaggtccaaatctt gcctggggtccattatgactcccaaaagtttgaccagaggacccagggacaagcctacccctccagatgagcttctacct caagctatcgaatttgtcaaccaatattacggctccttcaaagaggcaaaaatagaggaacatctggccagggtggaagc ggtaacaaaggagatagaaacaacaggaacctaccaactgacgggagatgagct atcttcgccaccaagcaggcctggc gcaatgccccacgctgcattgggaggatccagtggtccaacctgcaggtcttcgatgcccgcagctgttccactgcccgg gaaatgtttgaacacatctgcagacacgtgcgttactccaccaacaatggcaacatcaggtcggccatcaccgtgttccc ccagcggagtgatggcaagcacgacttccgggtgtggaatgctcagctcatccgctatgctggctaccagatgccagatg gcagcatcagaggggaccctgccaacgtggaattcactcagctgtgcatcgacctgggctggaagcccaagtacggccgc ttcgatgtggtccccctggtcctgcaggccaatggccgtgaccctgagctcttcgaaatcccacctgaccttgtgcttga ggtggccatggaacatcccaaatacgagtggtttcgggaactggagctaaagtggtacgccctgcctgcagtggccaaca tgctgcttgaggtgggcggcctggagttcccagggtgccccttcaatggctggtacatgggcacagagatcggagtccgg gacttctgtgacgtccagcgctacaacatcctggaggaagtgggcaggagaatgggcctggaaacgcacaagctggcctc gc ctggaaagaccaggctgtcgttgagatcaacattgctgtgatccatagttttcagaagcagaatgtgaccatcatgg accaccactcggctgcagaatccttcatgaagtacatgcagaatgaataccggtcccgtgggggctgcccggcagactgg atttggctggtccctcccatgtctgggagcatcacccccgtgtttcaccaggagatgctgaactacgtcctgtccccttt ctactactatcaggtagaggcctggaaaacccatgtctggcaggacgagaagcggagacccaagagaagagagattccat tgaaagtcttggtcaaagctgtgctctttgcctgtatgctgatgcgcaagacaatggcgtcccgagtcagagtcaccatc ctctttgcgacagagacaggaaaatcagaggcgctggcctgggacctgggggccttattcagctgtgccttcaaccccaa ggttgtctgcatggataagtacaggctgagctgcctggaggaggaacggctgctgttggtggtgaccagtacgtttggca atggagactgccctggcaatggagagaaactgaagaaatcgctcttcatgctgaaagagctcaacaacaaattcaggtac gctgtgtttggcctcggctccagcatgtaccctcggttctgcgcctttgctcatgacattgatcagaagctgtcccacct gggggcctctcagctcaccccgatgggagaaggggatgagctcagtgggcaggaggacgccttccgcagctgggccgtgc aaaccttcaaggcagcctgtgagacgtttgatgtccgaggcaaacagcacattcagatccccaagctctacacctccaat gtgacctgggacccgcaccactacaggctcgtgcaggactcacagcctttggacctcagcaaagccctcagcagcatgca tgccaagaacgtgttcaccatgaggctcaaatctcggcagaatctacaaagtccgacatccagccgtgccaccatcctgg tggaactctcctgtgaggatggccaaggcctgaactacctgccgggggagcaccttggggtttgcccaggcaaccagccg gccctggtccaaggcatcctggagcgagtggtggatggccccacaccccaccagacagtgcgcctggaggacctggatga gagtggcagctactgggtcagtgacaagaggctgcccccctgctcactcagccaggccctcacctactccccggacatca ccacacccccaacccagctgctgctccaaaagctggcccaggtggccacagaagagcctgagagacagaggctggaggcc ctgtgccagccctcagagtacagcaagtggaagttcaccaacagccccacattcctggaggtgctagaggagttcccgtc cctgcgggtgtctgctggcttcctgctttcccagctccccattctgaagcccaggttctactccatcagctcctcccggg atcacacgcccacggagatccacctgactgtggccgtggtcacctaccacaccggagatggccagggtcccctgcaccac ggtgtctgcagcacatggctcaacagcctgaagccccaagacccagtgccctgctttgtgcggaatgccagcgccttcca cctccccgaggatccctcccatccttgcatcc catcgggcctggcacaggcatcgtgcccttccgcagtttctggcagc aacggctccatgactcccagcacaagggagtgcggggaggccgcatgaccttggtgtttgggtgccgccgcccagatgag gaccacatctaccaggaggagatgctggagatggcccagaagggggtgctgcatgcggtgcacacagcctattcccgcct gcctggcaagcccaaggtctatgttcaggacatcctgcggcagcagctggccagcgaggtgctccgtgtgctccacaagg agccaggccacctctatgtttgcggggatgtgcgcatggcccgggacgtggcccacaccctgaagcagctggtggctgcc aagctgaaattgaatgaggagcaggtcgaggactatttctttcagctcaagagccagaagcgctatcacgaagatatctt cggtgctgtatttccttacgaggcgaagaaggacagggtggcggtgcagcccagcagcctggagatgtcagcgctctgag ggcctacaggaggggttaaagctgccggcacagaacttaaggatggagccagctctgcattatctgaggtcacagggcct ggggagatggaggaaagtgatatcccccagcctcaagtcttatttcctcaacgttgctccccatcaagccctttacttga cctcctaacaagtagcaccctggattgatcggagcctcctctctcaaactggggcctccctggtcccttggagacaaaat cttaaatgccaggcctggcgagtgggtgaaagatggaacttgctgctgagtgcaccacttcaagtgaccaccaggaggtg ctatcgcaccactgtgtatttaactgccttgtgtacagttatttatgcctctgtatttaaaaaactaacacccagtctgt tccccatggccacttgggtcttccctgtatgattccttgatggagatatttacatgaattgcattttactttaatcgaat tcccactctgctgcctgctccagcagacggacgcacagtaacatgggcaacttgaagagcgtggcccaggagcctgggcc accctgcggcctggggctggggctgggccttgggctgtgcggcaagcagggcccagccaccccggcccctgagcccagcc gggccccagcatccctactcccaccagcgccagaacacagccccccgagctccccgctaacccagcccccagaggggccc aagttccctcgtgtgaagaactgggaggtggggagcatcacctatgacaccctcagcgcccaggcgcagcaggatgggcc ctgcaccccaagacgctgcctgggctccctggtatttccacggaaactacagggccggccctcccccggccccccggccc ctgagcagctgctgagtcaggcccgggacttcatcaaccagtactacagctccattaagaggagcggctcccaggcccac gaacagcggcttcaagaggtggaagccgaggtggcagccacaggcacctaccagcttagggagagcgagctggtgttcgg ggctaagcaggcctggcgcaacgctccccgctgcgtgggccggatccagtgggggaagctgcaggtgttcgatgcccggg actgcaggtctgcacaggaaatgttcacctacatctgcaaccacatcaagtatgccaccaaccggggcaaccttcgctcg gccatcacagtgttcccgcagcgctgccctggccgaggagacttccgaatctggaacagccagctggtgcgctacgcggg ctaccggcagcaggacggctctgtgcggggggacccagccaacgtggagatcaccgagctctgcattcagcacggctgga ccccaggaaacggtcgcttcgacgtgctgcccctgctgctgcaggccccagatgagcccccagaactcttccttctgccc cccgagctggtccttgaggtgcccctggagcaccccacgctggagtggtttgcagccctgggcctgcgctggtacgccct cccggcagtgtccaacatgctgctggaaattgggggcctggagttccccgcagcccccttcagtggctggtacatgagca ctgagatcggcacgaggaacctgtgtgaccctcaccgctacaacatcctggaggatgtggctgtctgcatggacctggat acccggaccacctcgtccctgtggaaagacaaggcagcagtggaaatcaacgtggccgtgctgcacagttaccagctagc caaagtcaccatcgtggaccaccacgccgccacggcctctttcatgaagcacctggagaatgagcagaaggccagggggg gctgccctgcagactgggcctggatcgtgccccccatctcgggcagcctcactcctgttttccatcaggagatggtcaac tatttcctgtccccggccttccgctaccagccagacccctggaaggggagtgccgccaagggcaccggcatcaccaggaa gaagacctttaaagaagtggccaacgccgtgaagatctccgcctcgctcatgggcacggtgatggcgaagcgagtgaagg cgacaatcctgtatggctccgagaccggccgggcccagagctacgcacagcagctggggagactcttccggaaggctttt gatccccgggtcctgtgtatggatgagtatgacgtggtgtccctcgaacacgagacgctggtgctggtggtaaccagcac atttgggaatggggatcccccggagaatggagagagctttgcagctgccctgatggagatgtccggcccctacaacagct cccctcggccggaacagcacaagagttataagatccgcttcaacagcatctcctgctcagacccactggtgtcctcttgg cggcggaagaggaaggagtccagtaacacagacagtgcaggggccctgggcaccctcaggttctgtgtgttcgggc cgg ctcccgggcatacccccacttctgcgcctttgctcgtgccgtggacacacggctggaggaactgggcggggagcggctgc tgcagctgggccagggcgacgagctgtgcggccaggaggaggccttccgaggctgggcccaggctgccttccaggccgcc tgtgagaccttctgtgtgggagaggatgccaaggccgccgcccgagacatcttcagccccaaacggagctggaagcgcca gaggtaccggctgagcgcccaggccgagggcctgcagttgctgccaggtctgatccacgtgcacaggcggaagatgttcc aggctacaatccgctcagtggaaaacctgcaaagcagcaagtccacgagggccaccatcctggtgcgcctggacaccgga ggccaggaggggctgcagtaccagccgggggaccacataggtgtctgcccgcccaaccggcccggccttgtggaggcgct gctgagccgcgtggaggacccgccggcgcccactgagcccgtggcagtagagcagctggagaagggcagccctggtggcc ctccccccggctgggtgcgggacccccggctgcccccgtgcacgctgcgccaggctctcaccttcttcctggacatcacc tccccacccagccctcagctcttgcggctgctcagcaccttggcagaagagcccagggaacagcaggagctggaggccct cagccaggatccccgacgctacgaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcagttcccgt cggtggcgctgcctgccccactgctcctcacccagctgcctctgctccagccccggtactactcagtcagctcggcaccc agcacccacccaggagagatccacctcactgtagctgtgctggcatacaggactcaggatgggctgggccccctgcacta tggagtctgctccacgtggctaagccagctcaagcccggagaccctgtgccctgσttcatccggggggctccctccttcc ggctgccacccgatcccagcttgccctgcatcctggtgggtccaggcactggcattgcccccttccggggattctggcag gagcggctgcatgacattgagagcaaagggctgcagcccactcccatgactttggtgttcggctgccgatgctcccaact tgaccatctctaccgcgacgaggtgcagaacgcccagcagcgcggggtgtttggccgagtcctcaccgccttctcccggg aacctgacaaccccaagacctacgtgcaggacatcctgaggacggagctggctgcggaggtgcaccgcgtgctgtgcctc gagcggggccacatgtttgtctgcggcgatgttaccatggcaaccaacgtcctgcagaccgtgcagcgcatcctggcgac ggagggcgacatggagctggacgaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaagacattt tcgggctcacgctgcgcacccaggaggtgacaagccgcatacgcacccagagcttttccttgcaggagcgtcagttgcgg ggcgcagtgccctgggcgttcgaccctcccggctcagacaccaacagcccctgagagccgcctggctttcccttccagtt ccgggagagcggctgcccgactcaggtccgcccgaccaggatcagccccgctcctcccctcttgaggtggtgccttctca catctgtccagaggctgcaaggattcagcattattcctccaggaaggagcaaaacgcctcttttccctctctaggcctgt tgcctcgggcctgggtccgccttaatctggaaggcccctcccagcagcggtaccccagggcctactgccacccgcttcct gt tcttagtccgaatgttagattcctcttgcctctctcaggagtatcttacctgtaaagtctaatctctaaatcaagta tttattattgaagatttaccataagggactgtgccagatgttaggagaactactaaagtgcctaccccagctc (SEQ ID NO: 11878) gctgtagctggtgagaggaagtcctagaggctatggacactctgctgctgggatcaccgagatgagcagcagctgctcag ggctgagcagggtcctggtggccgtggctacagccctggtgtctgcctcctccccctgcccccaggcctggggcccccca ggggtccagtatgggcagccagggaggtccgtgaagctgtgttgtcctggagtgactgccggggacccagtgtcctggtt tcgggatggggagccaaagctgctccagggacctgactctgggctagggcatgaactggtcctggcccaggcagacagca ctgatgagggcacctacatctgccagaccctggatggtgcacttgggggcacagtgaccctgcagctgggctaccctcca gcccgccctgttgtctcctgccaagcagccgactatgagaacttctcttgcacttggagtcccagccagatcagcggttt acccacccgctacctcacctcctacaggaagaagacagtcctaggagctgatagccagaggaggagtccatccacagggc cctggccatgcccacaggatcccctaggggctgcccgctgtgttgtccacggggctgagttctggagccagtaccggatt aatgtgactgaggtgaacccactgggtgccagcacacgcctgctggatgtgagcttgcagagcatcttgcgccctgaccc accccagggcctgcgggtagagtcagtaccaggttacccccgacgcctgcgagccagctggacataccctgcctcctggc cgtgccagccccacttcctgctcaagttccgtttgcagtaccgtccggcgcagcatccagcctggtccacggtggagcca gctggactggaggaggtgatcacagatgctgtggctgggctgccccatgctgtacgagtcagtgcccgggactttctaga tgctggcacctggagcacctggagcccggaggcctggggaactccgagcactgggaccataccaaaggagataccagcat ggggccagctacacacgcagccagaggtggagcctcaggtggacagccctgctcctccaaggccctccctccaaccacac cctcggctacttgatcacagggactctgtggagcaggtagctgtgctggcgtctttgggaatcctttctttcctgggact ggtggctggggccctggcactggggctctggctgaggctgagacggggtgggaaggatggatccccaaagcctgggttct tggcctcagtgattccagtggacaggcgtccaggagctccaaacctgtagaggacccaggagggcttcggcagattccac ctataattctgtcttgctggtgtggatagaaaccaggcaggacagtagatccctatggttggatctcagctggaagttct gt tggagcccatttctgtgagaccctgtatttcaaatttgcagctgaaaggtgcttgtacσtctgatttcaccccagag ttggagttctgctcaaggaacgtgtgtaatgtgtacatctgtgtccatgtgtgaccatgtgtctgtgaaggccagggaac atgtattcctctgcatgcatgtatgtaggtgcctgggagtgtgtgtggtccttgctctggccctttcccttgcagggttg tgcaggtgtgaataaa (SEQ ID NO:11893) ggaagatgagcagcagctgctcagggctgagcagggtcctggtggccgtggctacagccctggtgtctgcctcctccccc tgcccccaggcctggggccccccaggggtccagtatgggcagccaggcaggtccgtgaagctgtgttgtcctggagtgac tgccggggacccagtgtcctggtttcgggatggggagccaaagctgctccagggacctgactctgggctagggcatgaac tggtcctggcccaggcagacagcactgatgagggcacctacatctgccagaccctggatggtgcacttgggggcacagtg accctgcagctgggctaccctccagcccgccctgttgtctcctgccaagcagccgactatgagaacttctcttgcacttg gagtcccagccagatcagcggtttacccacccgctacctcacctcctacaggaagaagacagtcctaggagctgatagcc agaggaggagtccatccacagggccctggccatgcccacaggatcccctaggggctgcccgctgtgttgtccacggggct gagttctggagccagtaccggattaatgtgactgaggtgaacccactgggtgccagcacacgcctgctggatgtgagctt gcagagcatcttgcgccctgacccaccccagggcctgcgggtagagtcagtaccaggttacccccgacgcctgcgagcca gctggacataccctgcctcctggccgtgccagccccacttcctgctcaagttccgtttgcagtaccgtccggcgcagcat ccagcctggtccacggtggagccagctggactggaggaggtgatcacagatgctgtggctgggctgccccatgctgtacg agtcagtgcccgggactttctagatgctggcacctggagcacctggagcccggaggcctggggaactccgagcactggga ccataccaaaggagataccagcatggggccagctacacacgcagccagaggtggagcctcaggtggacagccctgctcct ccaaggccctccctccaaccacaccctcggctacttgatcacagggactctgtggagcaggtagctgtgctggcgtcttt gggaatcctttctttcctgggactggtggctggggccctggcactggggctctggctgaggctgagacggggtgggaagg atggatccccaaagcctgggttcttggcctcagtgattccagtggacaggcgtccaggagctccaaacctgtagaggacc caggagggcttcggcagattccacctataattctgtcttgctggtgtggatagaaaccaggcaggacagtagatccctat ggttggatctcagctggaagttctgtttggagcccatttctgtgagaccctgtatttcaaatttgcagctgaaaggtgct tctacctctgatttcaccccagagttggagttctgctcaaggaacgtgtgtaatgtgtacatctgtgtccatgtgtgacc atgtgtctgtgaggcagggaacatgtattctctgcatgcatgtatgtaggtgcctggggagtgtgtgtgggtccttggct cttggcctttccttgcaggggttgtgcaggtgtgaataaagagaataaggaagttcttggagattatactcagaaaaaaa aa (SEQ ID NO: 11894) tctgtggagcaggtagctgtgctggcgtctttgggaatcctttctttcctgggactggtggctggggccctggcactggg gctctggtaagtgactgccattggtccctcagcctctgatcctcacacatgctctgatgcccatagaccacattcatctc cacccttcatgactgcctgctgaacctgtctgattctggaactacctccccatacctccatcccctatgccccacttgat tttaactgattcctctcctgaccctttactaataaaccctttggcggagactgagataacccacattgttggagagacag ctgcctttctatgccccaggctgaggctgagacggggtgggaaggatggatccccaaagcctgggttcttggcctcagtg attccagtggaca (SEQ ID NO: 11895) gctgtagctggtgagaggaagtcctagaggctatggacactctgctgctgggatcaccgagatgagcagcagctgctcag ggctgagcagggtcctggtggccgtggctacagccctggtgtctgcctcctccccctgcccccaggcctggggcccccca ggggtccagtatgggcagccagggaggtccgtgaagctgtgttgtcctggagtgactgccggggacccagtgtcctggtt tcgggatggggagccaaagctgctccagggacctgactctgggctagggcatgaactggtcctggcccaggcagacagca ctgatgagggcacctacatctgccagaccctggatggtgcacttgggggcacagtgaccctgcagctgggctaccctcca gcccgccctgttgtctcctgccaagcagccgactatgagaacttctcttgcacttggagtcccagccagatcagcggttt acccacccgctacctcacctcctacaggaagaagacagtcctaggagctgatagccagaggaggagtccatccacagggc cctggccatgcccacaggatcccctaggggctgcccgctgtgttgtccacggggctgagttctggagccagtaccggatt aatgtgactgaggtgaacccactgggtgccagcacacgcctgctggatgtgagcttgcagagcatcttgcgccctgaccc accccagggcctgcgggtagagtcagtaccaggttacccccgacgcctgcgagccagctggacataccctgcctcctggc cgtgccagccccacttcctgctcaagttccgtttgcagtaccgtccggcgcagcatccagcctggtccacggtggagcca gctggactggaggaggtgatcacagatgctgtggctgggctgccccatgctgtacgagtcagtgcccgggactttctaga tgctggcacctggagcacctggagcccggaggcctggggaactccgagcactgggaccataccaaaggagataccagcat ggggccagctacacacgcagccagaggtggagcctcaggtggacagccctgctcctccaaggccctccctccaaccacac cctcggctacttgatcacagggactctgtggagcaggtagctgtgctggcgtctttgggaatcctttctttcctgggact ggtggctggggccctggcactggggctctggctgaggctgagacggggtgggaaggatggatccccaaagcctgggttct tggcctcagtgattccagtggacaggcgtccaggagctccaaacctgtagaggacccaggagggcttcggcagattccac ctataattctgtcttgctggtgtggatagaaaccaggcaggacagtagatccctatggttggatctcagctggaagttct gtttggagcccatttctgtgagaccctgtatttcaaatttgcagctgaaaggtgcttgtacctctgatttcaccccagag ttggagttctgctcaaggaacgtgtgtaatgtgtacatctgtgtccatgtgtgaccatgtgtctgtgaaggccagggaac atgtattcctctgcatgcatgtatgtaggtgcctgggagtgtgtgtggtccttgctctggccctttcccttgcagggttg tgcaggtgtgaataaaggaagatgagcagcagctgctcagggctgagcagggtcctggtggccgtggctacagccctggt gtctgcctcctccccctgcccccaggcctggggccccccaggggtccagtatgggcagccaggcaggtccgtgaagctgt gttgtcctggagtgactgccggggacccagtgtcctggtttcgggatggggagccaaagctgctccagggacctgactct gggctagggcatgaactggtcctggcccaggcagacagcactgatgagggcacctacatctgccagaccctggatggtgc acttgggggcacagtgaccctgcagctgggctaccctccagcccgccctgttgtctcctgccaagcagccgactatgaga acttctcttgcacttggagtcccagccagatcagcggtttacccacccgctacctcacctcctacaggaagaagacagtc ctaggagctgatagccagaggaggagtccatccacagggccctggccatgcccacaggatcccctaggggctgcccgctg tgttgtccacggggctgagttctggagccagtaccggattaatgtgactgaggtgaacccactgggtgccagcacacgcc tgctggatgtgagcttgcagagcatcttgcgccctgacccaccccagggcctgcgggtagagtcagtaccaggttacccc cgacgcctgcgagccagctggacataccctgcctcctggccgtgccagccccacttcctgctcaagttccgtttgcagta ccgtccggcgcagcatccagcctggtccacggtggagccagctggactggaggaggtgatcacagatgctgtggctgggc tgccccatgctgtacgagtcagtgcccgggactttctagatgctggcacctggagcacctggagcccggaggcctgggga actccgagcactgggaccataccaaaggagataccagcatggggccagctacacacgcagccagaggtggagcctcaggt ggacagccctgctcctccaaggccctccctccaaccacaccctcggctacttgatcacagggactctgtggagcaggtag ctgtgctggcgtctttgggaatcctttctttcctgggactggtggctggggccctggcactggggctctggctgaggctg agacggggtgggaaggatggatccccaaagcctgggttcttggcctcagtgattccagtggacaggcgtccaggagctcc aaacctgtagaggacccaggagggcttcggcagattccacctataattctgtcttgctggtgtggatagaaaccaggcag gacagtagatccctatggttggatctcagctggaagttctgtttggagcccatttctgtgagaccctgtatttcaaattt gcagctgaaaggtgcttctacctctgatttcaccccagagttggagttctgctcaaggaacgtgtgtaatgtgtacatct gtgtccatgtgtgaccatgtgtctgtgaggcagggaacatgtattctctgcatgcatgtatgtaggtgcctggggagtgt gtgtgggtccttggctcttggcctttccttgcaggggttgtgcaggtgtgaataaagagaataaggaagttcttggagat tatactcagaaaaaaaaatctgtggagcaggtagctgtgctggcgtctttgggaatcctttctttcctgggactggtggc tggggccctggcactggggctctggtaagtgactgccattggtccctcagcctctgatcctcacacatgctctgatgccc atagaccacattcatctccacccttcatgactgcctgctgaacctgtctgattctggaactacctccccatacctccatc ccctatgccccacttgattttaactgattcctctcctgaccctttactaataaaccctttggcggagactgagataaccc acattgttggagagacagctgcctttctatgccccaggctgaggctgagacggggtgggaaggatggatccccaaagcct gggttcttggcctcagtgattccagtggaca (SEQ ID NO: 11896) cttcaactcaataagcattttaagtattctaatcttagtatttctctagctgacatgtaagaagcaatctatcttattgt atgcaattagctcattgtgtggataaaaaggtaaaaccattctgaaacaggaaaccaatacacttcctgtttaatcaaca aatctaaacatttattcttttcatctgtttactcttgctcttgtccaccacaatatgctattcacatgttcagtgtagtt ttatgacaaagaaaattttctgagttacttttgtatccccacccccttaaagaaaggaggaaaaactgtttcatacagaa ggcgttaattgcatgaattagagctatcacctaagtgtgggctaatgtaacaaagagggatttcacctacatccattcag tcagtctttgggggtttaaagaaattccaaagagtcatcagaagaggaaaaatgaaggtaatgttttttcagacaggtaa agtctttgaaaatatgtgtaatatgtaaaacattttgacacccccataatatttttccagaattaacagtataaattgca tctcttgttcaagagttccctatcactctctttaatcactactcacagtaacctcaactcctgccacaatgtacaggatg caactcctgtcttgcattgcactaagtcttgcacttgtcacaaacagtgcacctacttcaagttctacaaagaaaacaca gctacaactggagcatttacttctggatttacagatgattttgaatggaattaatgtaagtatatttcctttcttactaa aattattacatttagtaatctagctggagatcatttcttataacaatgcattatactttcttagaattacaagaatccca aactcaccaggatgctcacatttaagttttacatgcccaagaaggtaagtacaatatttt (SEQ ID NO: 11897) gaattcccttttcctagtcaaagaaaggggtgacagacagcacctggaaaatcgtgtcactcccaccctaatactgcgct tttccaatggtcttagcaaacagcacaccaagagattatatccagcacctggctcagagggtcctatgcccacggagcct cactcactgctagcacagcagtctgagatcaaactgcaaggtggcagtgaggctgggagaggggtgtgcaccattgccga ggcttgagtaggtaaacaaagcagctgggaagctcgaactgggtggagcccactgcagctcaaggaggcctgcctgcctc tgtagactccacctccgggggcagggcatagccaaacaaaaggcagcagaaacctctgcagacttaaatgtccctgtctg acagcttggaagagagtagtggttctcccagcatgcagcttgagatctgagaatggacagactgcctcctcaagtgggtc cctgacccccgagtaacctaactgggaggcaccccaagtaggggcagactgacacctcacatggctgggtactcctctga gaaaaaacttccagaggaacgatcaggcagcaacatttgctgttcaccaatatccactgttctgcagcctcctgtgctaa tacccaggcaaatgggtctggagaggacctccagcaagctccaacagacctacagctgagggtcctgactgttagaagga aaactaacaaacagaaaggacatccacaccaaaaccctatctgtacggcaccatcatcaaagaccaaaggtagataaaac cacaaagatggggaaaaaaacacagcagaaaaactggtaactctaaaaattagagcgcttctcctcctccaaaggaacgc agctcctcaccagcaatggaaccaagctggacagagaatgactttgacgagttgagagaagaaggcttcagatgatcaaa ctactctgagctaaaggaggaagttcgaacccacggcaaagaagttaaaaaccttgaaaaaaattagatgaatggctaac tagaataaccaatgcagagaagtccttaaaggacctgatggagctgaaaaccatggcacaagaactacatgacaaatgca caagcctcagtagctgattcgatcaactggaagaaagggtatcagtgatggaagatcaaatgaatgaaatgaagcaagaa gagaagtttagagaaaaaagaaaaaaaagaaatgaacaaagcctccaagaaatatgggactatgtgaaaagaccaaatct acgtctgattggtgtacctgaaagtgatggggagaatggaaccaagctggaaaacactctgcaggatattatccaagaga acttccccaatctagcaaggcaggctgacattcaaattcaggaaatacagagaacgccacaaatataatcctcgagaaga gcaactccaagacacataattgttagattcactaaagttgaaatgaaggaaaaaatgttaagggcagccagagagaaagg tcagcttacccacaaaggaaagcccatcagattaacagctgatctctcggcagaaactctacaagccagaagagagtggg ggccaatattcaacattcttaaagaaaagaattttcaacccagaatttcatatccagccaaactatgcttcataagtgaa ggagaaataaaatatagacaagtgaacgatgaaagattttgtcaccaccaggcctgccctacaagagctcctgaaggaag cactaaacatggaaaggaacaaccggtaccagccactgcaaaaacatgccaaattgtaaacaccattgaggccaggaaga aactgcatcaactaacgagcaaaataaccagctaacatcatcatgacaggatcaaattcacacataacaatattaacctt aaatgtaaataggctaaatgctccaattaaaagacacagactggcaaactggataaagagtcaagacccatcagtgtgct gtattcaggaaacccatctcacgtgcagagacacacataggctcaaaataaagggatggaggaagatctaccaaacaaac ggaaaacaaaaaaaggcaggggttgcaatcctagtctctgataaaacagactttaaaccaacaaagatcaaaagagacac agaaggccattacataatggtaaagggatcaattcaacaagaagagttaactatcctaaatatatatgcacccaatacag gagcacctagattcataaagcaagtccttagagacctacaaagagacttagactcccacacaataataatgggagacttt aacaccccactgtcaacattagacagatcaatgagacagaaaattaacaaggatatccaggaattgaactcaactctgca ccaagcggacctaatagacatctacagaactctccaccccaaatcaacagaatatacattcttttcggcaccacaccaca ccgattccaaaattgaacacatagttggaagtaaagcactcctcagcaaatgtaaaagaacagaaagtacaacaaactgt ctctcagaccacagtgcaatcaaactaaaactcaggattaagaaactcactcaaaaccgctcaactacatggaaactgaa caacctgctcctgaatgactactgggtacataacgaaatgaaggcagaagtaaagatgttctttgaaaccaacgagaaca aagacacaacataccagaatctctgggacacattcaaagcagtgtgtagaggaaaatttatagcactaaatgcccacaag agaaagcaggaaagatctaaaattgacagcctaacatcacaattaaaagaactagagaaacaagagcaaacacattcaaa agctagcagaaggcaagaaataactacaatcagagcagaactgaaggagatagagacatacaaaaaacccttcaaaaaat caatgaatccaggagctggttttttgaaaagatcaacaaaattgatagaccactagcaaaactaatacagaagagagaag aatcaaatagacacaataaaaaatgataaacgggatatcaccactgatcccacagaaatacaaactaccatcaaagaata ctataaacacctctatgcaaataaactagaaaatctagaagaaatggataaattcctcgacacatacaccctcccaagac taaaccaggaagaagctgaatctctgaatagaccaataacaggctctgaaattgaggcaacaattaacaccttaccaacc aataaaagtccaggaccagatggattcacagccaaattctaccagaggtacaaggaggagctggtacgattccttctgaa actattccaatcaatagaaaaagagggaatcctccctaactcattttatgaggccagcatcatcctgataccaaagcctg gcagagacacaacaaaaaaagagaatttcagaccaatatccctgatgaacatcgatgcaaaaatttttaataaaatactg gcaaactgaatccagcagcacatcacaaagcttatccaccatgatcaagctggcttcattcctgggatgcaaggctggtt caacatacggaaaatcaataaatgtaatccagcatataaacagaaccaacaacacacaacacatgat atctcaacagat gcagaaaaggcctttgacaaaattcaacagcccttcatgctaaaaactctcaataaattaggtactgatgggacgtatct caaaataataagcgctatctatgaccaacccacagccaatatcatactggatgggcaaaaactggaagcattccctttga aaactggcacaagacagggatgccctctctcaccactcctattcaacacagtgttcgaagttctggcagggcaatcaggc aggagaaagaaataaagggtattcaattaggaaaagaggaggtcaaattgtccctgtttgcagatgacatgattgtatat atagaaaaccccattgtctcagcccaaaatctccttaagctgataagcaacttcagcaaagtctcaggatcaaaatcaat gtgcaaaaatcacaagcattcttatacaccaataacagacaaacagagagccaaatcatgagtgaactcccattcacaat tgcttcaaagagaataaaatacctaggaatccaactcacaagggatgtgagagacctcttcaaggagaactataaaccac tgctcaatgaaatgagaggatacagataaatggaagaacattccatgctcatgggtaggaagaatcaatatcgtgaaaat ggccatactgcccaaggtaattttatagattcaatgccatccccatcaagctaccaatgactttcttcacagaattggaa aaaac actttaaagttcatatggaaccaaaaaagagcccgcattgccaagtcaatcctaagccaaaagaacaaagctag aggcatcacactacctgacttcaaactatactacaaggctacagtaaccaaaacagcatggtactggtaccaaagcagag atatagaccaatggaacaaaacagtgccctcagaaataatactgcatatctacaaccatctgatctttgacaaacctgac aaaaacaagcaatggggaaaggattccctatttaataaatggtgctgggaaaactggctagccatatgtagaaagctgaa attggatcccttccttacaccttgtacaaaaattaattcaagatggattacagacttaaatgttagacctaaaaccataa aaaccctagaagaaaacctaggcaataccattcaggacataggcatgggcaagaacttcatgtctagaacaccaaaagta atggcaacaaaagccaaaattgacaaatgggtctaattaaactaaagagcttctgcacagcaaaagaaactaccatcaga gtgaagaggcaacctacagaatgggagaaaatttttgcaatctgacaaaagggctaatttttgcatctgacaaagggcta atatccagaatctacaatgaactcaaacaaatttacaagaaaaaaacaaatttacaagaaaaaaacaaaatttacaagaa aaaaacaaatttacaagaaaaaaacaaacaaccccatcaaaaagtgggcaaaggataagaacagtcacttctcaaaagaa gacatttatgcagccaaaagacacatgaaaaaattctcatcatcactggccatcagagaaatgcaaatcaaaaccacaat gagataccatctcacaccagttagaatggcgatcattaaaaagtcaagaaacaacaggtgctggagaggatgtggagaaa taggaacacttttacactgttagtgggactgtaaactagttcaacattgtggaaatcagtatggcgattcctcagggatc tagaactagaaataccatttgacccagccatcccattactgggtatatacccaaaggattataaatcatgctgctataaa gacacttgcacacatatgtttattgtggtactattcacaatagcaaagacttggaattaacccaaatgtccaacaatgat agactagattaagaaaatgtggcacatatacactatggaatactttgcagccataaaaaaggatgagttcatgtcctttg tagggacatggatgaagctggaaaccatcattctcggcaaactatcgcaaggtcaaaaaaccaaacaccgcatgttctca ctcataggtggtaactgaacaatgagaacacatggtcacaggaaggggaacatcacgcactggggcctgttgtggggtgg ggggagtgggcagggatagcattaggagacatacctaatgttaaatgacgatttaatgggtgcagcacaccaacatggca catgtatacatatgtaacaaacccacacgttgtgcacatgtactctaaaacttaaagtataattaaaataaataaataaa gtaaaaaagaaatcctaaggatactcaaattgttgtttaggtgaagatggatgatgccttccttgaatcatcagctacca ccgacagagtgaagtgagatggaatagtgggcacaatctcattcatcctactctatgtagcctaatgggtccagaattta tcatcactattttacactggaaaaaagatgagattatgaggggtcagggaggctttgagtttttgctctaacttcaccac taattaagaatgtgatcttgggtaagccactttaacctctgtaaatgtcaaatttcttatcagtaaaatgtgactataca agacaataaatttgaaaatactttgcaaaattgaaagtaccatggaaataattcttcaatcccaaaaggttatgaacatt attaaaatttgccacatggaagagcacacaccacagagacataactgtgatcataaacagatttacaaaagtggtgtttc attatggagggccatagggctgataaagacaaatgcatcaccaagctatgtccgagctcattcagatttttacaggaaac acagagcttctagctgaattatctctggatggtgtggaaattgtccaacacgttcctaatttcaaagaaacagaactgaa tcttgaaaacccaagaggcctttacagaaactgacaagagatgaattaatataggtatcaagctacagaccaaattaaag ttttacaaaactttgaaagagggtcagaaagaagaaacttatgggaagcagagtcctggaaagtcagctttgatggagtg acaatatgtgcaacacagtgagcaatctcttaggtaggcagcttcagggatgggggttgccctttgaaaggacttgggcc actcttgagtctaagaggctaagtcacaaacaatgctaagcaactaaaaatagcttcttgtttaatagtaaaattctgca tagtaaaaggagaagcagggggtatgacacacgtggtagttagcagtctactagtgactttactgccacaaccagaaaag ccagctgatgtgtcagacgtgagaaagcgaaagtatgtcacagcgaatgtagcttttccacacgtatttcaagaaagaaa tgaaaaaggccaacttctataatggtgcctactgtgcattaacagagataaactaggggtctaagaactcagttttctac agggtcccagaagtat gccatatattgccccattctctaatggaaatagccagagaaatagaaatatcaagactggaga acatcaaatacctcattggaaaagcccccacataggaaaatgtgtgggcttgaattcttccattctggaagggtaaaggc ctgagtgatgatgctgggattagacactgaaactctttagagaagcaaaacaagtataataaagctgtactttattatat taaataaataacacacagactaccaaatagcctgccccttataacagcgttaatgtgattttgatctgaaatgtatagag acattttgcattttttcggtataaaaagttcatgagatttggccctaatctggaccttttcttcatttttttttctactt gagggactataatctttatttttaaatttgttttatattctccgaacattacctaacgcatagaaaactcttcttgaacc atttttctctgttctttgtaaaatattacatttgactgttccttagactgctttaatcattcctgcctatgcaccctcct caaaatccagtttaaattaattgttccttattcaagattccttatatccacctcccttggggcagcaatcacctatcacc caggactacacttgtgtatgtacatatcttccctattacaaatcaggttctttgaaaaaatacaaatggtaagagagtgg atttttggagtcagtacattctcttttcaaatccttcttctgccccttactggcaataagggctgagtgacctagagcaa attacttaacttctctgagcctcagttttctaatctgcaaaataggagccatcacttcacaagtctgtaagacttatatt agactaagtgcctgcctgtacactgttctcttttctctctttctatatacctgaaggcattataggtgctagatgtctgt ttaaagaccagacaatattgtcttaaaaaaacaaacaaaaacacagacaataccatctttaaaaaaaaaaaaaagtccag gtaagaaataaataaggccatagaatggaagctttacaaggactctctgtgagacaggatctcctcaagtgtccccaggt taaattagaagtatatatccgtacaattgttcagccagtttgtgcactgtactgaggatgaatgaacacctatcctaaat atcctagtcttctgactaaaaacaagatcatatttcataacgattattgttacattcatagtgtcccaggtgatttagag gataaataaaaatccattaaagaggtaaagacataaaaacgagaaacatggactggtttacacataacacatacaaagtc tattataaaactagcatcagtatccttgaatgcaaacctttttctgagtatttaacaatcgcaccctttaaaaaatgtac aatagacattaagagacttaaacagatatataatca ttaaattaaaatagcgttaaacagtacctcaagctcaataag cattttaagtattctaatcttagtatttctctagctgacatgtaagaagcaatctatcttattgtatgcaattagctcat tgtgtggataaaaaggtaaaaccattctgaaacaggaaaccaatacacttcctgtttaatcaacaaatctaaacatttat tcttttcatctgtttactcttgctgttgtccaccacaatatgctattσacatgttcagtgtagttttatgacaaagaaaa ttttctgagttacttttgtatccccacccccttaaagaaaggaggaaaaactgtttcatacagaaggcgttaattgcatg aattagagctatcacctaagtgtgggctaatgtaacaaagagggatttcacctacatccattcagtcagtctttgggggt ttaaagaaattccaaagagtcatcagaagaggaaaaatgaaggtaatgttttttcagacaggtaaagtctttgaaaatat gtgtaatatgtaaaacattttgacacccccataatatttttccagaattaacagtataaattgcatctcttgttcaagag ttccctatcactctctttaatcactactcacagtaacctcaactcctgccacaatgtac (SEQ ID NO: 11898) ttaatcaacaaatctaaacatttattcttttcatctgtttactcttgctcttgttcaccacaatatgctattcacatgtt cagtgtagttttatgacaaagaaaattttctgagttacttttgtatccccacccccttaaagaaaggaggaaaaactgtt tcatacagaaggcgttaattgcatgaattagagctatcacctaagtgtgggctaatgtaacaaagagggatttcacctac atccattcagtcagtctttgggggtttaaagaattccaaagagtcatcagaagaggaaaaatgaaggtaatgttttttca gacaggtaaagtctttgaaaatatgtgtaatatgtaaaacattttgacacccccataatatttttccagaattaacagta taaattgcatctcttgttcaagagttcccta cactctctttaatcactactcacagtaacctcaactcctgccacaatg tacaggatgcaactcctgtcttgcattgcactaagtcttgcacttgtcacaaacagtgcacctacttcaagttctacaaa gaaaacacagctacaactggagcatttactgctggatttacagatgattttgaatggaattaatgtaagtatatttcctt tcttactaaaattattacatttagtaatctagctggagatcatttcttaataacaatgcattatactttcttagaattac aagaatcccaaactcaccaggatgctcacatttaagttttacatgcccaagaaggtaagtacaatattt atgt caatt tctgttttaataaaattcaaagtaatatgaaaatttgcacagatgggactaatagcagctcatctgaggtaaagagtaac tttaatttgtttttttgaaaacccaagtttgataatgaagcctctattaaaacagttttacctatatttttaatatatat ttgtgtgttggtgggggtgggaagaaaacataaaaataatattctcacctttatcgataagacaattctaaacaaaaatg ttcatttatggtttcatttaaaaatgtaaaactctaaaatatttgattatgtcattttagtatgtaaaataccaaaatct atttccaaggagcccacttttaaaaatcttttcttgttttaggaaaggtttctaagtgagaggcagcataacactaatag cacagagtctggggccagatatctgaagtgaaatctcagctctgccatgtcctagctttcatgatctttggcaaattacc tactctgtttgtgattcagtttcatgtctacttaaatgaataactgtatatacttaatatggctttgtgagaattagtaa gtt aatgtaaagcactcagaaccgtgtctggcataaggtaaataccatacaagcattagctattattagtagtattaaa gataaaattttcactgagaaatacaaagtaaaattttggactttatctttttaccaatagaacttgagatttataatgct atatgacttattttccaagattaaaagcttcattaggttgtttttggattcagatagagcataagcataatcatccaagc tcctaggctacattaggtgtgtaaagctacctagtagttgtgccagttaagagagaatgaacaaaatctggtgccagaaa gagcttgtgccagggtgaatccaagcccagaaaataataggatttaaggggacacagatgcaatcccattgactcaaatt ctattaattcaagagaaatctgcttctaactacccttctgaaagatgtaaaggagacagcttacagatgttactctagtt taatcagagccacataatgcaactccagcaacataaagatactagatgctgttttctgaagaaaatttctccacattgtt catgccaaaaacttaaacccgaatttgtagaatttgtagtggtgaattgaaagcgcaatagatggacatatcaggggatt ggtattgtcttgacctacctttcccactaaagagtgttagaaagatgagattatgtgcataatttagggggtggtagaat tcatggaaatctaagtttgaaaccaaaagtaatgataaactctattcatttgttcatttaaccctcattgcacatttaca aaagattttagaaactaataaaaatatttgattccaaggatgctatgttaatgctataatgagaaagaaatgaaatctaa ttctggctctacctacttatgtggtcaaattctgagatttagtgtgcttatttataaagtggagatgatacttcactgcc tacttcaaaagatgactgtgagaagtaaatgggcctattttggagaaaattcttttaaattgtaatataccatagaaata tgaaatattatatataatatagaatcaagaggcctgtccaaaagtcctcccaaagtattataatcttttatttcactggg acaaacatttttaaaatgcatcttaatgtagtgattgtagaaaagtaaaatttaagacatatttaaaaatgtgtcttgct caaggctatattgagagccactactacatgattattgttacctagtgtaaaatgttgggattgtgatagatggcattcaa gagttccttctctctcaacattctgtgattcttaactcttagactatcaaatattataatcatagaatgtgatttttatg cttccacattctaactcatctggttctaatgattttctatgcagattggaaaagtaatcagcctgcatctgtgataggca cttacgatgcagaaagtctaacattttgcaaagccaaattaagctaaaaccagtgagtcaactatcacttaacgctagtc ataggtacttgagccctagtttttccagttttataatgtaaactctactggtccattctttacagtgacattgagaacag agagaatggtaaaaactacatactgctactccaaataaaataaattggaaattaatttctgattctgacctctatgtaaa ctgagctgatgataattattattctaggccacagaactgaaacatcttcagtgtctagaagaagaactcaaacctctgga ggaagtgctaaatttagctcaaagcaaaaactttcacttaagacccagggacttaatcagcaatatcaacgtaatagttc tggaactaaaggtaaggcattactttatttgctctcctggaaataaaaaaaaaaaagtcagggggaaaagtaccacattt taaagtgacataacatttttggtatttgtaaagtacccatgcatgtaattagcctacattttaagtacactgtgaacatg aatcatttctaatgttaaatgattaactggggagtataagctactgagtttgcacctaccatctactaatggacaagcct catcccaaactccatcacctttcatattaacacaaaactgggagtgagagaaggtactgagttgagtttcacagaaagca ggcagattttattatatatttttcgattcttcagatcatttactgaaatagccaatactgattacctgaaaggcttttca aatgg gt ccttatcatttgatggaaggactacccataagagatttgtcttaaaaaaaaaaactggagccattaaaat ggccagtggactaaacaaacaacaatctttttagaggcaatccccactttcagaatcttaagtatttttaaatgcacagg aagcataaaatatgcaagggactcaggtgatgtaaaagagattcacttttgtctttttatatcccgtctcctaaggtata aaattcatgagttaataggtatcctaaataagcagcataagtatagtagtaaaagacattcctaaaagtaactccagttg tgtccaaatgaatcacttattagtggactgtttcagttgaattaaaaaaatacattgagatcaatgtcatctagacattg acagattcagttccttatctatggcaagagttttactctaaaataattaacatcagaaaactcattcttaactcttgata caaatttaagacaaaaccatgcaaaaatctgaaaactgtgtttcaaaagccaaacactttttaaaataaaaaatcccaag atatgacaatatttaaacaattatgcttaagaggatacagaacactgcaacagttttttaaaagagaatacttatttaaa gggaacactctatctcacctgcttttgttcccagggtaggaatcacttcaaatttgaaaagctctcttttaaatctcact atatatcaaaatatttcctccttagcttatcaactagaggaagcgtttaaatagctcctttcagcagagaagcctaattt ctaaaaagccagtccacagaacaaaatttctaatgtttaaacttttaaaagttggcaaattcacctgcattgatactatg atggggtagggataggtgtaagtatttagaagatgttcttcacacaaatttatcccaaacggaagcatgtcctagcttac tctagtgtagttctgttctgctttggggaaaatataaggagattcacttaagtagaaaaataggagactctaatcaagat ttagaaaagaagaaagtataatgtgcatatcaattcatacatttaacttacacaaatataggtgtacattcagaggaaaa gcgatcaagtttatttcacatccagcatttaatatttgtctagatctatttttatttaaatctttatttgcacccaattt agggaaaaaatttttgtgttcattgactgaattaacaaatgaggaaaatctcagcttctgtgttactatcatttggtatc ataacaaaatatgtaattttggcattcattttgatcatttcaagaaaatgcgaataattaatatgtttggtaagcttgaa aataaaggcaacaggcctataagacttcaattgggaataactgtatataaggtaaactactctgtactttaaaaaattaa catttttcttttatagggatctgaaacaacattcatgtgtgaatatgctgatgagacagcaaccattgtagaatttctga acagatggattaccttttgtcaaagcatcatctcaacactgacttgataattaagtgcttcccacttaaaacatatcagg ccttctatttatttaaatatttaaattttatatttattgttgaatgtatggtttgctacctattgtaactattattctta atcttaaaactataaatatggatcttttatgattctttttgtgccctaggggctctaaaatggtttcacttat tatccc aaaatatttattattatgttgaatgttaaatatagtgctatgtagattggttagtaaaactatttaataaatttgataaa tataaacaagcctggatatttgttattttggaaacagcacagagtaagcatttaaatatttcttagttacttgtgtgaac tgtaggatggttaaaatgcttacaaaagtcactctttctctgaagaaatatgtagaacagagatgtagacttctcaaaag cccttgctttgtcctttcaagggctgatcagacccttagttctggcatctcttagcagattatattttccttcttcttaa aatgccaaacacaaacactcttgaaactcttcatagatttggtgtggctatgaattc (SEQ ID NO: 11899) cgaattcccctatcacctaagtgtgggctaatgtaacaaagagggatttcacctacatccattcagtcagtctttggggg tttaaagaaattccaaagagtcatcagaagaggaaaaatgaaggtaatgttttttcagactggtaaagtctttgaaaata tgtgtaatatgtaaaacattttgacacccccataatatttttccagaattaacagtataaattgcatctcttgttcaaga gttccctatcactctttaatcactactcacagtaacctcaactcctgccacaatgtacaggatgcaactcctgtcttgca ttgcactaagtcttgcacttgtcacaaacagtgcacctacttcaagttctacaaagaaaacacagctacaactggagcat ttactgctggatttacagatgattttgaatggaattaatgtaagtatatttcctttcttactaaaattattacatttagt aatctagctggagatcatttcttaataacaatgcattatactttcttagaattacaagaatcccaaactcaccaggatgc tcacatttaagttttacatgcccaagaaggtaagtacaatattttatgttcaatttctgttttaataaaattcaaagtaa tatgaaaatttgcacagatgggactaatagcagctcatctgaggtaaagagtaactttaatttgtttttttgaaaaccca agtttgataatgaagcctctattaaaacagttttacctatatttttaatatatatttgtgtgttggtgggggtgggagaa aacataaaaataatattctctcactttatcgataagacaattctaaacaaaaatgttcatttatggtttcatttaaaaat gtaaaactctaaaatatttgattatgtcattttagtatgtaaaataccaaaatctatttccaaggagcccacttttaaaa atcttttcttgttttaggaaaggtttctaagtgagaggcagcataacactaatagcacagagtctggggccagatatctg aagtgaaatctcagctctgccatgtcctagctttcatgatctttggcaaattacctactctgtttgtgattcagtttcat gtctacttaaatgaataactgtatatacttaatatggctttgtgagaattagtaagtaaatgtaaagcactcagaaccgt gtctggcataaggtaaataccatacaagcattagctattattagtagtattaaagataaaattttcactgagaaatacaa agtaaaattttggactttatctttttaccaatagaacttgagatttataatgctatatgacttattttccaagattaaaa gcttcattaggttgtttttggattcagatagagcataagcataatcatccaagctcctaggctacattaggtgtgtaaag ctacctagtagctgtgccagttaagagagaatgaacaaaatctggtgccagaaagagcttgtgccagggtgaatccaagc ccagaaaataataggatttaaggggacacagatgcaatcccattgactcaaattctattaattcaagagaaatctgcttc taactacccttctgaaagatgtaaaggagacagcttacagatgttactctagtttaatcagagccacataatgcaactcc agcaacataaagatactagatgctgttttctgaagaaaatttctccacattgttcatgccaaaaacttaaacccgaattt gtagaatttgtagtggtgaattgaaagcgcaatagatggacatatcaggggattggtattgtcttgacctacctttccca ctaaagagtgttagaaagatgagattatgtgcataatttaggggtggtagaattcatggaaatctaagtttgaaaccaaa agtaatgataaactctattcatttgttcatttaaccctcattgcacatttacaaaagattttagaaactaataaaaatat ttgattccaaggatgctatgttaatgctataatgagaaagaaatgaaatctaattctggctctacctacttatgtggtca aattctgagatttagtgtgcttatttataaagtggagatgatacttcactgcctacttcaaaagatgactgtgagaagta aatgggcctattttggagaaaattcttttaaattgtaatataccatagaaatatgaaatattatatataatatagaatca agaggcctgtccaaaagtcctcccaaagtattataatcttttatttcactgggacaaacatttttaaaatgcatcttaat gtagtgattgtagaaaagtaaaaatttaagacatatttaaaaatgtgtcttgctcaaggctatattgagagccactacta catgattattgttacctagtgtaaaatgttgggattgtgatagatggcatccaagagttccttctctctcaacattctgt gattcttaactcttagactatcaaatattataatcatagaatgtgatttttatgccttccacattctaatctcatctggt tctaatgattttctatgcagattggaaaagtaatcagcctacatctgtaataggcatttagatgcagaaagtctaacatt ttgcaaagccaaattaagctaaaaccagtgagtcaactatcacttaacgctagtcataggtacttgagccctagtttttc cagttttataatgtaaactctactggtccatctttacagtgacattgagaacagagagaatggtaaaaactacatactgc tactccaaataaaataaattggaaattaatttctgattctgacctctatgtaaactgagctgatgataattattattcta ggccacagaactgaaacatcttcagtgtctagaagaagaactcaaacctctggaggaagtgctaaatttagctcaaagca aaaactttcacttaagacccagggacttaatcagcaatatcaacgtaatagttctggaactaaaggtaaggcattacttt atttgctctcctggaaataaaaaaaaaaaagtagggggaaaagtaccacattttaaagtgacataacatttttggtattt gtaaagtacccatgcatgtaattagcctacattttaagtacactgtgaacatgaatcatttctaatgttaaatgattaac tggggagtataagctactgagtttgcacctaccatctactaatggacaagcctca cccaaactccatcacctttcatat taacacaaaactgggagtgagagagaagtgactgagttgagtttcacagaaacgcaggcaagattttattatatattttt caagttccttcacagatcatttactggaatagccaatactgagttacctgaaaggcttttcaaatggtgtttccttatca tttgatggaaggactacccataagagatttgtcttaaaaaaaaaaactggagccattaaaatggccagtggactaaacaa acaacaatctttttagaggcaatcccactttcagaatcttaagtatttttaaatgcacaggaagcataaaatatgcaagg gactcaggtgatgtaaaagagattcacttttgtctttttatatcccgtctcctaaggtataaaattcatgagttaatagg tatcctaaataagcagcataagtatagtagtaaaagacattcctaaaagtaactccagttgtgtccaaatgaatcactta ttagtggactgtttcagttgaattaaaaaaatacattgagatcaatgtcatctagacattgacagattcagttccttatc tatggcaagagttttactctaaaataattaacatcagaaaactcattcttaactcttgatacaaatttaagacaaaacca tgcaaaaatctgaaaactgtgtttcaaaagccaaacactttttaaaataaaaaaatcccaagatatgacaatatttaaac aattatgcttaagaggatacagaacactgcaacagttttttaaaagagaatacttatttaaagggaacactctatctcac ctgcttttgttcccagggtaggaatcacttcaaatttgaaaagctctcttttaaatctcactatatatcaaaatagttgc ctccttagcttatcaactagaggaagcgtttaaatagctcctttcagcagagaagcctaatttctaaaaagccagtccac agaacaaaatttctaatgtttaaagcttttaaaagttggcaaattcacctgcattgatactatgatggggtagggatagg tgtaagtatttatgaagatgttcattcacacaaatttacccaaacaggaagcatgtcctacctagcttactctagtgtag ctcgtttcgtctttggggaaaatataaggagattcacttaagtagaaaaataggagactctaatcaagatttagaaaaga agaaagtataatgtgcatatcaattcatacatttaacttacacaaatataggtgtacattcagaggaaaagcgatcaagt ttatttcacatccagcatttaatatttgtctagatctatttttatttaaatctttatttgcacccaatttagggaaaaaa tttttgtgttcattgactgaattaacaaatgaggaaaatctcagcttctgtgttactatcatttggtatcataacaaaat acgcaattttggcattcattttgatcatttcaagaaaatgtgaataattaatatgtttggtaagcttgaaaataaaggca acaggcctataagacttcaattgggaataactgtatataaggtaaactactctgtactttaaaaaattaacatttttctt ttatagggatctgaaacaacattcatgtgtgaatatgctgatgagacagcaaccattgtagaatttctgaacagatggat taccttttgtcaaagcatcatctcaacactgacttgataattaagtgcttcccacttaaaacatatcaggccttctattt atttaaatatttaaattttatatttattgttgaatgtatggtttgctacctattgtaactattattcttaatcttaaaac tataaatatggatcttttatgattctttttgtaagccctaggggctctaaaatggtttcacttatttatcccaaaatatt tattattatgttgaatgttaaatatagtatctatgtagattggttagtaaaactatttaataaatttgataaatataaac aagcctggatatttgttattttggaaacagcacagagtaagcatttaaatatttcttagttacttgtgtgaactgtagga tggttaaaatgcttacaaaagtcactctttctctgaagaaatatgtagaacagagatgtagacttctcaaaagcccttgc tttgtcctttcaagggctgatcagacccttagttctggcatctcttagcagattatattttccttcttcttaaaatgcca aacacaaacactcttgaaactcttcatagatttggtgtggc (SEQ ID NO: 11900) ccccataatatttttccagaattaacagtataaattgcatctcttgttcaagagttccctatcactctctttaatcacta ctcacagtaacctcaactcctgccacaatgtacaggatgcaactcctgtcttgcattgcactaagtcttgcacttgtcac aaacagtgcacctacttcaagttctacaaagaaaacacagctacaactggagcatttactgctggatttacagatgattt tgaatggaattaataattacaagaatcccaaactcaccaggatgctcacatttaagttttacatgcccaagaaggccaca gaactgaaacatcttcagtgtctagaagaagaactcaaacctctggaggaagtgctaaatttagctcaaagcaaaaactt tcacttaagacccagggacttaatcagcaatatcaacgtaatagttctggaactaaagggatctgaaacaacattcatgt gtgaatatgctgatgagacagcaaccattgtagaatttctgaacagatggattaccttttgtcaaagcatcatctcaaca ctgacttgataattaagtgcttcccacttaaaacatatcaggccttctatttatttaaatatttaaattttatatttatt gttgaatgtatggtttgctacctattgtaactattattcttaatcttaaaactataaatatggatcttttatgattcttt ttgtaagccctaggggctctaaaatggtttcactta ttatcccaaaatat tat attatgttgaatgttaaatatagt atctatgtagattggttagtaaaactatttaataaatttgataa (SEQ ID NO: 11901) cttcaactcaataagcattttaagtattctaatcttagtatttctctagctgacatgtaagaagcaatctatcttattgt atgcaattagctcattgtgtggataaaaaggtaaaaccattctgaaacaggaaaccaatacacttcctgtttaatcaaca aatctaaacatttattcttttcatctgtttactcttgctcttgtccaccacaatatgctattcacatgttcagtgtagtt ttatgacaaagaaaattttctgagttacttttgtatccccacccccttaaagaaaggaggaaaaactgtttcatacagaa ggcgttaattgcatgaattagagctatcacctaagtgtgggctaatgtaacaaagagggatttcacctacatccattcag tcagtctttgggggtttaaagaaattccaaagagtcatcagaagaggaaaaatgaaggtaatgttttttcagacaggtaa agtctttgaaaatatgtgtaatatgtaaaacattttgacacccccataatatttttccagaattaacagtataaattgca tctcttgttcaagagttccctatcactctctttaatcactactcacagtaacctcaactcctgccacaatgtacaggatg caactcctgtcttgcattgcactaagtcttgcacttgtcacaaacagtgcacctacttcaagttctacaaagaaaacaca gctacaactggagcatttacttctggatttacagatgattttgaatggaattaatgtaagtatatttcctttcttactaa aattattacatttagtaatctagctggagatcatttcttataacaatgcattatactttcttagaattacaagaatccca aactcaccaggatgctcacatttaagttttacatgcccaagaaggtaagtacaatattttgaattcccttttcctagtca aagaaaggggtgacagacagcacctggaaaatcgtgtcactcccaccctaatactgcgcttttccaatggtcttagcaaa cagcacaccaagagattatatccagcacctggctcagagggtcctatgcccacggagcctcactcactgctagcacagca gtctgagatcaaactgcaaggtggcagtgaggctgggagaggggtgtgcaccattgccgaggcttgagtaggtaaacaaa gcagctgggaagctcgaactgggtggagcccactgcagctcaaggaggcctgcctgcctctgtagactccacctccgggg gcagggcatagccaaacaaaaggcagcagaaacctctgcagacttaaatgtccctgtctgacagcttggaagagagtagt ggttctcccagcatgcagcttgagatctgagaatggacagactgcctcctcaagtgggtccctgacccccgagtaaccta actgggaggcaccccaagtaggggcagactgacacctcacatggctgggtactcctctgagaaaaaacttccagaggaac gatcaggcagcaacatttgctgttcaccaatatccactgttctgcagcctcctgtgctaatacccaggcaaatgggtctg gagaggacctccagcaagctccaacagacctacagctgagggtcctgactgttagaaggaaaactaacaaacagaaagga catccacaccaaaaccctatctgtacggcaccatcatcaaagaccaaaggtagataaaaccacaaagatggggaaaaaaa cacagcagaaaaactggtaactctaaaaattagagcgcttctcctcctccaaaggaacgcagctcctcaccagcaatgga accaagctggacagagaatgactttgacgagttgagagaagaaggcttcagatgatcaaactactctgagctaaaggagg aagttcgaacccacggcaaagaagttaaaaaccttgaaaaaaattagatgaatggctaactagaataaccaatgcagaga agtccttaaaggacctgatggagctgaaaaccatggcacaagaactacatgacaaatgcacaagcctcagtagctgattc gatcaactggaagaaagggtatcagtgatggaagatcaaatgaatgaaatgaagcaagaagagaagtttagagaaaaaag 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agcgtttaaatagctcctttcagcagagaagcctaatttctaaaaagccagtccacagaacaaaatttctaatgtttaaa cttttaaaagttggcaaattcacctgcattgatactatgatggggtagggataggtgtaagtatttagaagatgttcttc acacaaatttatcccaaacggaagcatgtcctagcttactctagtgtagttctgttctgctttggggaaaatataaggag attcacttaagtagaaaaataggagactctaatcaagatttagaaaagaagaaagtataatgtgcatatcaattcataca tttaacttacacaaatataggtgtacattcagaggaaaagcgatcaagtttatttcacatccagcatttaatatttgtct agatctatttttatttaaatctttatttgcacccaatttagggaaaaaatttttgtgttcattgactgaattaacaaatg aggaaaatctcagcttctgtgttactatcatttggtatcataacaaaatatgtaattttggcattcattttgatcatttc aagaaaatgcgaataattaatatgtttggtaagcttgaaaataaaggcaacaggcctataagacttcaattgggaataac tgtatataaggtaaactactctgtactttaaaaaattaacatttttcttttatagggatctgaaacaacattcatgtgtg aatatgctgatgagacagcaaccattgtagaatttctgaacagatggattaccttttgtcaaagcatcatctcaacactg acttgataattaagtgcttcccacttaaaacatatcaggccttctatttatttaaatatttaaattttatatttattgtt gaatgtatggtttgctacctattgtaactattattcttaatcttaaaactataaatatggatcttttatgattctttttg tgccctaggggctctaaaatggtttcacttatttatcccaaaatatttattattatgttgaatgttaaatatagtgctat gtagattggttagtaaaactatttaataaatttgataaatataaacaagcctggatatttgttattttggaaacagcaca gagtaagcatttaaatatttcttagttacttgtgtgaactgtaggatggttaaaatgcttacaaaagtcactctttctct gaagaaatatgtagaacagagatgtagacttctcaaaagcccttgctttgtcctttcaagggctgatcagacccttagtt ctggcatctcttagcagattatattttccttcttcttaaaatgccaaacacaaacactcttgaaactcttcatagatttg gtgtggctatgaattccgaattcccctatcacctaagtgtgggctaatgtaacaaagagggatttcacctacatccattc agtcagtctttgggggtttaaagaaattccaaagagtcatcagaagaggaaaaatgaaggtaatgttttttcagactggt aaagtctttgaaaatatgtgtaatatgtaaaacattttgacacccccataatatttttccagaattaacagtataaattg catctcttgttcaagagttccctatcactctttaatcactactcacagtaacctcaactcctgccacaatgtacaggatg caactcctgtcttgcattgcactaagtcttgcacttgtcacaaacagtgcacctacttcaagttctacaaagaaaacaca gctacaactggagcatttactgctggatttacagatgattttgaatggaattaatgtaagtatatttcctttcttactaa aattattacatttagtaatctagctggagatcatttcttaataacaatgcattatactttcttagaattacaagaatccc aaactcaccaggatgctcacatttaagttttacatgcccaagaaggtaagtacaatattttatgttcaatttctgtttta ataaaattcaaagtaatatgaaaatttgcacagatgggactaatagcagctcatctgaggtaaagagtaactttaatttg tttttttgaaaacccaagtttgataatgaagcctctattaaaacagttttacctatatttttaatatatatttgtgtgtt ggtgggggtgggagaaaacataaaaataatattctctcactttatcgataagacaattctaaacaaaaatgttcatttat ggtttcatttaaaaatgtaaaactctaaaatatttgattatgtcattttagtatgtaaaataccaaaatctatttccaag gagcccacttttaaaaatcttttcttgttttaggaaaggtttctaagtgagaggcagcataacactaatagcacagagtc tggggccagatatctgaagtgaaatctcagctctgccatgtcctagctttcatgatctttggcaaattacctactctgtt tgtgattcagtttcatgtctacttaaatgaataactgtatatacttaatatggctttgtgagaattagtaagtaaatgta aagcactcagaaccgtgtctggcataaggtaaataccatacaagcattagctattattagtagtattaaagataaaattt tcactgagaaatacaaagtaaaattttggactttatctttttaccaatagaacttgagatttataatgctatatgactta ttttccaagattaaaagcttcattaggttgtttttggattcagatagagcataagcataatcatccaagctcctaggcta cattaggtgtgtaaagctacctagtagctgtgccagttaagagagaatgaacaaaatctggtgccagaaagagcttgtgc cagggtgaatccaagcccagaaaataataggatttaaggggacacagatgcaatcccattgactcaaattctattaattc aagagaaatctgcttctaactacccttctgaaagatgtaaaggagacagcttacagatgttactctagtttaatcagagc cacataatgcaactccagcaacataaagatactagatgctgttttctgaagaaaatttctccacattgttcatgccaaaa acttaaacccgaatttgtagaatttgtagtggtgaattgaaagcgcaatagatggacatatcaggggattggtattgtct tgacctacctttcccactaaagagtgttagaaagatgagattatgtgcataatttaggggtggtagaattcatggaaatc taagtttgaaaccaaaagtaatgataaactctattcatttgttcatttaaccctcattgcacatttacaaaagattttag aaactaataaaaatatttgattccaaggatgctatgttaatgctataatgagaaagaaatgaaatctaattctggctcta cctacttatgtggtcaaattctgagatttagtgtgcttatttataaagtggagatgatacttcactgcctacttcaaaag atgactgtgagaagtaaatgggcctattttggagaaaattcttttaaattgtaatataccatagaaatatgaaatattat atataatatagaatcaagaggcctgtccaaaagtcctcccaaagtattataatcttttatttcactgggacaaacatttt taaaatgcatcttaatgtagtgattgtagaaaagtaaaaatttaagacatatttaaaaatgtgtcttgctcaaggctata ttgagagccactactacatgattattgttacctagtgtaaaatgttgggattgtgatagatggcatccaagagttccttc tctctcaacattctgtgattcttaactcttagactatcaaatattataatcatagaatgtgatttttatgccttccacat tctaatctcatctggttctaatgattttctatgcagattggaaaagtaatcagcctacatctgtaataggcatttagatg cagaaagtctaacattttgcaaagccaaattaagctaaaaccagtgagtcaactatcacttaacgctagtcataggtact tgagccctagtttttccagttttataatgtaaactctactggtccatctttacagtgacattgagaacagagagaatggt aaaaactacatactgctactccaaataaaataaattggaaattaatttctgattctgacctctatgtaaactgagctgat gataa ta at ctaggccacagaactgaaacatcttcagtgtctagaagaagaactcaaacctctggaggaagtgcta aatttagctcaaagcaaaaactttcacttaagacccagggacttaatcagcaatatcaacgtaatagttctggaactaaa ggtaaggcattactttatttgctctcctggaaataaaaaaaaaaaagtagggggaaaagtaccacattttaaagtgacat aacatttttggtatttgtaaagtacccatgcatgtaattagcctacattttaagtacactgtgaacatgaatcatttcta atgttaaatgattaactggggagtataagctactgagtttgcacctaccatctactaatggacaagcctcatcccaaact ccatcacctttcatattaacacaaaactgggagtgagagagaagtgactgagttgagtttcacagaaacgcaggcaagat tttattatatatttttcaagttccttcacagatcatttactggaatagccaatactgagttacctgaaaggcttttcaaa tggtgtttccttatcatttgatggaaggactacccataagagatttgtcttaaaaaaaaaaactggagccattaaaatgg ccagtggactaaacaaacaacaatctttttagaggcaatcccactttcagaatcttaagtatttttaaatgcacaggaag cataaaatatgcaagggactcaggtgatgtaaaagagattcacttttgtctttttatatcccgtctcctaaggtataaaa ttcatgagttaataggtatcctaaataagcagcataagtatagtagtaaaagacattcctaaaagtaactccagttgtgt ccaaatgaatcac tattagtggactgtttcagttgaattaaaaaaatacattgagatcaatgtca ctagacattgaca gattcagttccttatctatggcaagagttttactctaaaataattaacatcagaaaactcattcttaactcttgatacaa atttaagacaaaaccatgcaaaaatctgaaaactgtgtttcaaaagccaaacactttttaaaataaaaaaatcccaagat atgacaatatttaaacaattatgcttaagaggatacagaacactgcaacagttttttaaaagagaatacttatttaaagg gaacactctatctcacctgcttttgttcccagggtaggaatcacttcaaatttgaaaagctctcttttaaatctcactat atatcaaaatagttgcctccttagcttatcaactagaggaagcgtttaaatagctcctttcagcagagaagcctaatttc taaaaagccagtccacagaacaaaatttctaatgtttaaagcttttaaaagttggcaaattcacctgcattgatactatg atggggtagggataggtgtaagtatttatgaagatgttcattcacacaaatttacccaaacaggaagcatgtcctaccta gcttactctagtgtagctcgtttcgtctttggggaaaatataaggagattcacttaagtagaaaaataggagactctaat caagatttagaaaagaagaaagtataatgtgcatatcaattcatacatttaacttacacaaatataggtgtacattcaga ggaaaagcgatcaagtttatttcacatccagcatttaatatttgtctagatctatttttatttaaatctttatttgcacc caatttagggaaaaaatttttgtgttcattgactgaattaacaaatgaggaaaatctcagcttctgtgttactatcattt ggta cataacaaaatacgcaattttggcattcattttgatcatttcaagaaaatgtgaataattaatatgtttggtaag cttgaaaataaaggcaacaggcctataagacttcaattgggaataactgtatataaggtaaactactctg act taaaa aattaacatttttcttttatagggatctgaaacaacattcatgtgtgaatatgctgatgagacagcaaccattgtagaat ttctgaacagatggattaccttttgtcaaagcatcatctcaacactgacttgataattaagtgcttcccacttaaaacat atcaggccttctatttatttaaatatttaaattttatatttattgttgaatgtatggtttgctacctattgtaactat a ttcttaatcttaaaactataaatatggatcttttatgattctttttgtaagccctaggggctctaaaatggtttcactta tttatcccaaaatatttattattatgttgaatgttaaatatagtatctatgtagattggttagtaaaactatttaataaa tttgataaatataaacaagcctggatatttgttattttggaaacagcacagagtaagcatttaaatatttcttagttact tgtgtgaactgtaggatggttaaaatgcttacaaaagtcactctttctctgaagaaatatgtagaacagagatgtagact tctcaaaagcccttgctttgtcctttcaagggctgatcagacccttagttctggcatctcttagcagattatattttcct tcttcttaaaatgccaaacacaaacactcttgaaactcttcatagatttggtgtggcccccataatatttttccagaatt aacagtataaattgcatctcttgttcaagagttccctatcactctctttaatcactactcacagtaacctcaactcctgc cacaatgtacaggatgcaactcctgtcttgcattgcactaagtcttgcacttgtcacaaacagtgcacctacttcaagtt ctacaaagaaaacacagctacaactggagcatttactgctggatttacagatgattttgaatggaattaataattacaag aatcccaaactcaccaggatgctcacatttaagttttacatgcccaagaaggccacagaactgaaacatcttcagtgtct agaagaagaactcaaacctctggaggaagtgctaaatttagctcaaagcaaaaactttcacttaagacccagggacttaa tcagcaatatcaacgtaatagttctggaactaaagggatctgaaacaacattcatgtgtgaatatgctgatgagacagca accattgtagaatttctgaacagatggattaccttttgtcaaagcatcatctcaacactgacttgataattaagtgcttc ccacttaaaacatatcaggccttctatttatttaaatatttaaattttatatttattgttgaatgtatggtttgctacct attgtaactattattcttaatcttaaaactataaatatggatcttttatgattctttttgtaagccctaggggctctaaa atggtttcacttatttatcccaaaatatttattattatgttgaatgttaaatatagtatctatgtagattggttagtaaa actatttaataaatttgataa (SEQ ID NO:11902) aggcccagttgaaaccagggagttgctctcctttctcctcccttgacctcacccctcagaccatgccaattctgcctcct aaacctcccaggccagcccctcccccagctcccagtgacagtgtcctcaggtacctgagctcagctctcggtgctaccag agggactgcagggctgcagaggctgagtcccacacgcagggaacagccatgccactgctagcagaccagtaagagaatgg ccacctggggcctgagcgccctcggccatccaccagaaacaaagtgtcaaggagaagctgcccgaagcccatgggacaaa ccactggggactggaacaccagtaattctgtattgggaagcggcaccaagagatgtgcttctcagagcctgaggctgaac gtggatgtttagcagcgtgaccggctaccagacaaactctcatctgttccagtggcctcctggccacccaccaggaccaa gcagggcgggcagcagagggccagggtagtccaggtgatggcagatgagatcccactgggcaggaggcctcagtgagctg agtcaggcttccccttcctgccacaggggtcctctcacctgctgccatgcttcccatctctcatcctccttgacaagatg aagtgataccgtttaagtaatcttttttcttgtttcactgatcttgagtactagaaagtcatggatgaataattacgtct gtggttttctatggaggttccatgtcagataaagatccttccgacgcctgccccacaccaccacctcccccgccttgccc ggggttgtgggcaccttgctgctgcacatataaggcgggagctgttgccaactcttcagagccccacgaaggaccagaac aagacagagtgcctcctgccgatccaaacatgagccgcc (SEQ ID NO: 11903) gccacccaccaggaccaagcagggcgggcagcagagggccagggtagtccaggtgatggcagatgagatcccactgggca ggaggcctcagtgagctgagtcaggcttccccttcctgccacaggggtcctctcacctgctgccatgcttcccatctctc atcctccttgacaagatgaagtgataccgtttaagtaatcttttttcttgtttcactgatcttgagtactagaaagtcat ggatgaataattacgtctgtggttttctatggaggttccatgtcagataaagatccttccgacgcctgccccacaccacc acctccccccgccttgcccggggttgtgggcaccttgctgctgcacatataaggcgggaggttgttgccaactcttcaga gccccacgaaggaccagaacaagacagagtgcctcctgccgatccaaacatg (SEQ ID NO: 11904) gatccaggagaccagtctcctagtaccaggtctgcttgcctaaacttggagtataagagccatagacactgtctcttcga tcagtccttgcccccaccccctgctgttgcacccttatctttcaccctattgctcctgcattgaagacagaagcacccag tttcccctgcctcagcataacttgctagccttcatttcctcgtgctggtcacatcacaccacaacccgacccaaaccctg gtttctctaccatgcccctgcttccctgcaccccaggcttgtcacactcatcttctaccaaaactccagctttgtgctgt ggcctgtcaacctgtcccatggaaaagggggccaccccatccttcagggactgtcccctggctctccacactcctggctt tgccactttctctctagctgtggtttctcaggtcctttgagaacttcccataactgtccctgtttccttcccacctctgt aggcctgagctgcaaaccagctcccactccacccaggctccagggccgactgggatttagatccctcaatatggctttcc ttcagggagtagttctcttctctcctcttgccctcccggctcaaacttgtccatgccacctgctacaccgtcctgcagct cccagtaactaacactattctcaaggcccacctttgtccctaggtccctaagcctaattatctgagttatcagaaggatg gcctagtgtttgcagtcatatctccatcaagggttctgtcctctagatgtgggccttagcgcattgccttactgcactga gactagaccagtgaaggagtgagctgaactccatatccacctgcaaggaataagggtcaatgggaaggctgcctagaggg agagggagctctagctaccagcggccagaggactagcccacccatggacgtttaaccatgtgccagaatgcctaccatgt tcaagtttgccccagtgaccctggtggcccactaatagtggtggcccacagtcaggggcagatttgtacaagggatggta ggaagaggttccagtgcacagaaaccccaagctggctcggagccaggctacttcctcccaccacctgtttccactcggtc ca ctctatgacaaaggaagaagatggcctttgaataagcagtctttcttcccatgtcgataattttgagtactagaaaa cgatgaataagtctgtggtttgctatggaggttccatgtcagataaagctgcttctgatgcctgcccttccccccatgcc ctgcctggggcccgccccgcccctctcgatgaatatatataaggtgaaggctcctgtggcttcttcagaactctttggag gaccagaacgagacaatggttcttgccagctctaccaccagcatcctctgtatgctgctcccgctcctgatgctcttcca ccagggactccagatttcagacaggggctcagatgcccaccatttactcaggacgttggattgcaggactattgccttgg agattttggtgaagctcccagtgagtagctggctgaggttagcctgggcaggctggcttcaacaggtgcctcggaccaat aagcctcatgattctttcttttagtatcctcaggtatctggactcaataatagtgacgacaaagccaatctgagggtaag agccctgctcttgggcattcttgggttccatctgtctcctgcctgggtgactttagccatgtcactgcaccctgctttgc ttccgttttcacatctat tcagtggggttattaaggaaatcatcagatgactctctgagcctcagtctgtgccacagcc agctgcaataatgaaagttgcattttaggagatacaatggagagagaactgtgagtgaaccctgccacaggcctctggct ccactttcagtggggatgccatggggatgccatggaccagtgaacgagttgccttctgtgactgtgtcttttgcttttct tcctcctccaaaactgagcttgtgttctccacttccaccagcctaagacattaccatttgcagttattttcccagctcta gttagatacaatggttctgtttcgtttttatttgtttgcaagcgtgctgagtgtctacgtttcccctccctagggacatg atgaagtctgtaggattttcttctagatatctagaagttcttaattaaattaaagcattggggttggggatttagctcag tggtagagtgcttgcctagcaagcgcaaggccctgagttcattccccagctccgaaaaaaagaaaaaagaaaaagaaaaa aaattaaagcattaaccttggtgtttggcatcttgggcataagtatttcccttggccaaccttctgccttttctagagct tgtctggagagatatgtttcccttaaaaacagacagatctgcttagagccttcacacagtccacaggctgccaggggtta agacctggtgctcaggagaaacaggcccttgtctgggatgtgccctagctttagccccaggataaggaaaggaccaggag taaggctgttcaaagaaacctctaacagcagtcacacctccccagctctcacctccccagctctcacctccccagctctc acctctcccgctctcacctccccagctctcacctctccagctctcacttccccagttctcacctccccagctctcacctc tccagctctcacctccccagctctcacct (SEQ ID NO: 11905) cagagccccacgaaggaccagaacaagacagagtgcctcctgccgatccaaacatgagccgcctgcccgtcctgctcctg ctccaactcctggtccgccccggactccaagctcccatgacccagacaacgcccttgaagacaagctgggttaactgctc taacatgatcgatgaaattataacacacttaaagcagccacctttgcctttgctggacttcaacaacctcaatggggaag accaagacattctgatggaaaataaccttcgaaggccaaacctggaggcattcaacagggctgtcaagagtttacagaac gcatcagcaattgagagcattcttaaaaatctcctgccatgtctgcccctggccacggccgcacccacgcgacatccaat ccatatcaaggacggtgactggaatgaattccggaggaaactgacgttctatctgaaaacccttgagaatgcgcaggctc aacagacgactttgagcctcgcgatcttttagtccaacgtccagctcgttctctgggccttctcaccacagagcctcggg acatcaaaaacagcagaacttctgaaacctctgggtcatctctcacacattccaggaccagaagcatttcaccttttcct gcggcatcagatgaattgttaattatctaatttctgaaatgtgcagctcccatttggccttgtgcggttgtgttctcatt tttatcccattgagactatttatttatgtatgtatgtatttatttatttattgcctggagtgtgaactgtatttatttta gcagaggagccatgtcctgctgcttctgcaaaaaactcagagtggggtggggagcatgttcatttgtacctcgagtttta aactggttcctagggatgtgtgagaataaactagactctgaac (SEQ ID NO: 11906) tgtgtaagtaagtgcaagctacagagaaaaccaaggaagaaaaaaattgccagagatccaggttaaaaaaaaaaaaagaa aaagaaaagaaaaccaaggaagcaatcatcataaaagacaggtgagtgggttacctctaagggcgagcagtcacgattag aggacaaatatggggagagttttggagcgttggcgatttttttttgacttaagcatggttaaatgggtgattgcttataa ttacttgttaaattaggttaattaggttttatttacatgttttatgctcttttctgcatgcatttgtgctctattttttt aattaaaaaataaaataaagtaaaactatgtttcttgcacttaaaatactggaaaaccaaagagaatctgaaaaactttt agaatgaagagagtttggcaagacggcaagaacccttgctttttccactgggcctttcttcctcccaccctgagggtgct ccatggaaaatgcaaatctacttaactgactttcgcaaatgtcaaatgtagagtacgaatttcaaggggagcctggggct gtgccatatcctgctgtgagctacagttttccagcctctagagccatcttaacaaggtgcctgcctggtgtctactaccc cagtatgtgctccaacccctgcccaggcctcctagtgctagagaggatatagacatggcctctccatggaaacctccagg gctggtatgacaccttaacaaacaaaaagggaggattgccggtacagcggagtcccgcaggaggataggtgttgccttct aggtggtagggaggctgagagggccatccagagtagggaccacgaactggggtctcaacatgaagagtcgttcatcagat ct (SEQ ID Nθ:11907) aggcccagttgaaaccagggagttgctctcctttctcctcccttgacctcacccctcagaccatgccaattctgcctcct aaacctcccaggccagcccctcccccagctcccagtgacagtgtcctcaggtacctgagctcagctctcggtgctaccag agggactgcagggctgcagaggctgagtcccacacgcagggaacagccatgccactgctagcagaccagtaagagaatgg ccacctggggcctgagcgccctcggccatccaccagaaacaaagtgtcaaggagaagctgcccgaagcccatgggacaaa ccactggggactggaacaccagtaattctgtattgggaagcggcaccaagagatgtgcttctcagagcctgaggctgaac gtggatgtttagcagcgtgaccggctaccagacaaactctcatctgttccagtggcctcctggccacccaccaggaccaa gcagggcgggcagcagagggccagggtagtccaggtgatggcagatgagatcccactgggcaggaggcctcagtgagctg agtcaggcttccccttcctgccacaggggtcctctcacctgctgccatgcttcccatctctcatcctccttgacaagatg aagtgataccgtttaagtaatcttttttcttgtttcactgatcttgagtactagaaagtcatggatgaataattacgtct gtggttttctatggaggttccatgtcagataaagatccttccgacgcctgccccacaccaccacctcccccgccttgccc ggggttgtgggcaccttgctgctgcacatataaggcgggagctgttgccaactcttcagagccccacgaaggaccagaac aagacagagtgcctcctgccgatccaaacatgagccgccgccacccaccaggaccaagcagggcgggcagcagagggcca gggtagtccaggtgatggcagatgagatcccactgggcaggaggcctcagtgagctgagtcaggcttccccttcctgcca caggggtcctctcacctgctgccatgcttcccatctctcatcctccttgacaagatgaagtgataccgtttaagtaatct tttttcttgtttcactgatcttgagtactagaaagtcatggatgaataattacgtctgtggttttctatggaggttccat gtcagataaagatccttccgacgcctgccccacaccaccacctccccccgccttgcccggggttgtgggcaccttgctgc tgcacatataaggcgggaggttgttgccaactcttcagagccccacgaaggaccagaacaagacagagtgcctcctgccg atccaaacatggatccaggagaccagtctcctagtaccaggtctgcttgcctaaacttggagtataagagccatagacac tgtctcttcgatcagtccttgcccccaccccctgctgttgcacccttatctttcaccctattgctcctgcattgaagaca gaagcacccagtttcccctgcctcagcataacttgctagccttcatttcctcgtgctggtcacatcacaccacaacccga cccaaaccctggtttctctaccatgcccctgcttccctgcaccccaggcttgtcacactcatcttctaccaaaactccag ctttgtgctgtggcctgtcaacctgtcccatggaaaagggggccaccccatccttcagggactgtcccctggctctccac actcctggctttgccactttctctctagctgtggtttctcaggtcctttgagaacttcccataactgtccctgtttcctt cccacctctgtaggcctgagctgcaaaccagctcccactccacccaggctccagggccgactgggatttagatccctcaa tatggctttccttcagggagtagttctcttctctcctcttgccctcccggctcaaacttgtccatgccacctgctacacc gtcctgcagctcccagtaactaacactattctcaaggcccacctttgtccctaggtccctaagcctaattatctgagtta tcagaaggatggcctagtgtttgcagtcatatctccatcaagggttctgtcctctagatgtgggccttagcgcattgcct tactgcactgagactagaccagtgaaggagtgagctgaactccatatccacctgcaaggaataagggtcaatgggaaggc tgcctagagggagagggagctctagctaccagcggccagaggactagcccacccatggacgtttaaccatgtgccagaat gcctaccatgttcaagtttgccccagtgaccctggtggcccactaatagtggtggcccacagtcaggggcagatttgtac aagggatggtaggaagaggttccagtgcacagaaaccccaagctggctcggagccaggctacttcctcccaccacctgtt tccactcggtccatctctatgacaaaggaagaagatggcctttgaataagcagtctttcttcccatgtcgataattttga gtactagaaaacgatgaataagtctgtggtttgctatggaggttccatgtcagataaagctgcttctgatgcctgccctt ccccccatgccctgcctggggcccgccccgcccctctcgatgaatatatataaggtgaaggctcctgtggcttcttcaga actctttggaggaccagaacgagacaatggttcttgccagctctaccaccagcatcctctgtatgctgctcccgctcctg atgctcttccaccagggactccagatttcagacaggggctcagatgcccaccatttactcaggacgttggattgcaggac tattgccttggagattttggtgaagctcccagtgagtagctggctgaggttagcctgggcaggctggcttcaacaggtgc ctcggaccaataagcctcatgattctttcttttagtatcctcaggtatctggactcaataatagtgacgacaaagccaat ctgagggtaagagccctgctcttgggcattcttgggttccatctgtctcctgcctgggtgactttagccatgtcactgca ccctgctttgcttccgttttcacatctatctcagtggggttattaaggaaatcatcagatgactctctgagcctcagtct gtgccacagccagctgcaataatgaaagttgcattttaggagatacaatggagagagaactgtgagtgaaccctgccaca ggcctctggctccactttcagtggggatgccatggggatgccatggaccagtgaacgagttgccttctgtgactgtgtct tttgcttttcttcctcctccaaaactgagcttgtgttctccacttccaccagcctaagacattaccatttgcagttattt tcccagctctagttagatacaatggttctgtttcgtttttatttgtttgcaagcgtgctgagtgtctacgtttcccctcc ctagggacatgatgaagtctgtaggattttcttctagatatctagaagttcttaattaaattaaagcattggggttgggg atttagctcagtggtagagtgcttgcctagcaagcgcaaggccctgagttcattccccagctccgaaaaaaagaaaaaag aaaaagaaaaaaaattaaagcattaaccttggtgtttggcatcttgggcataagtatttcccttggccaaccttctgcct tttctagagcttgtctggagagatatgtttcccttaaaaacagacagatctgcttagagccttcacacagtccacaggct gccaggggttaagacctggtgctcaggagaaacaggcccttgtctgggatgtgccctagctttagccccaggataaggaa aggaccaggagtaaggctgttcaaagaaacctctaacagcagtcacacctccccagctctcacctccccagctctcacct ccccagctctcacctctcccgctctcacctccccagctctcacctctccagctctcacttccccagttctcacctcccca gctctcacctctccagctctcacctccccagctctcacctcagagccccacgaaggaccagaacaagacagagtgcctcc tgccgatccaaacatgagccgcctgcccgtcctgctcctgctccaactcctggtccgccccggactccaagctcccatga cccagacaacgcccttgaagacaagctgggttaactgctctaacatgatcgatgaaattataacacacttaaagcagcca cctttgcctttgctggacttcaacaacctcaatggggaagaccaagacattctgatggaaaataaccttcgaaggccaaa cctggaggcattcaacagggctgtcaagagtttacagaacgcatcagcaattgagagcattcttaaaaatctcctgccat gtctgcccctggccacggccgcacccacgcgacatccaatccatatcaaggacggtgactggaatgaattccggaggaaa ctgacgttctatctgaaaacccttgagaatgcgcaggctcaacagacgactttgagcctcgcgatcttttagtccaacgt ccagctcgttctctgggccttctcaccacagagcctcgggacatcaaaaacagcagaacttctgaaacctctgggtcatc tctcacacattccaggaccagaagcatttcaccttttcctgcggcatcagatgaattgttaattatctaatttctgaaat gtgcagctcccatttggccttgtgcggttgtgttctcatttttatcccattgagactatttatttatgtatgtatgtatt tatttatttattgcctggagtgtgaactgtatttattttagcagaggagccatgtcctgctgcttctgcaaaaaactcag agtggggtggggagcatgttcatttgtacctcgagttttaaactggttcctagggatgtgtgagaataaactagactctg aactgtgtaagtaagtgcaagctacagagaaaaccaaggaagaaaaaaattgccagagatccaggttaaaaaaaaaaaaa gaaaaagaaaagaaaaccaaggaagcaatcatcataaaagacaggtgagtgggttacctctaagggcgagcagtcacgat tagaggacaaatatggggagagttttggagcgttggcgatttttttttgacttaagcatggttaaatgggtgattgctta taattacttgttaaattaggttaattaggttt atttacatgttttatgctcttttctgcatgcatttgtgctctatttt tttaattaaaaaataaaataaagtaaaactatgtttcttgcacttaaaatactggaaaaccaaagagaatctgaaaaact tttagaatgaagagagtttggcaagacggcaagaacccttgctttttccactgggcctttcttcctcccaccctgagggt gctccatggaaaatgcaaatctacttaactgactttcgcaaatgtcaaatgtagagtacgaatttcaaggggagcctggg gctgtgccatatcctgctgtgagctacagttttccagcctctagagccatcttaacaaggtgcctgcctggtgtctacta ccccagtatgtgctccaacccctgcccaggcctcctagtgctagagaggatatagacatggcctctccatggaaacctcc agggctggtatgacaccttaacaaacaaaaagggaggattgccggtacagcggagtcccgcaggaggataggtgttgcct tctaggtggtagggaggctgagagggccatccagagtagggaccacgaactggggtctcaacatgaagagtcgttcatca gatct (SEQ ID NO:11908) gcacacgggaagatatcagaaacatcctaggatcaggacaccccagatcttctcaactggaaccacgaaggctgtttctt ccacacagcactttgatctccatttaagcaggcacctctgtcctgcgttccggagctgcgttcccgatggtcctcctttg gctcacgctgctcctgatcgccctgccctgtctcctgcaaacgaaggaagatccaaacccaccaatcacgaacctaagga tgaaagcaaaggctcagcagttgacctgggaccttaacagaaatgtgaccgatatcgagtgtgttaaagatgccgactat tctatgccggcagtgaacaatagctattgccagtttggagcaatttccttatgtgaagtgaccaactacaccgtccgagt ggccaacccaccattctccacgtggatcctcttccctgagaacagtgggaagccttgggcaggtgcggagaatctgacct gctggattcatgacgtggatttcttgagctgcagctgggcggtaggcccgggggcccccgcggacgtccagtacgacctg tacttgaacgttgccaacaggcgtcaacagtacgagtgtcttcactacaaaacggatgctcagggaacacgtatcgggtg tcgtttcgatgacatctctcgactctccagcggttctcaaagttcccacatcctggtgcggggcaggagcgcagccttcg gtatcccctgcacagataagtttgtcgtcttttcacagattgagatattaactccacccaacatgactgcaaagtgtaat aagacacattcctttatgcactggaaaatgagaagtcatttcaatcgcaaatttcgctatgagcttcagatacaaaagag aatgcagcctgtaatcacagaacaggtcagagacagaacctccttccagctactcaatcctggaacgtacacagtacaaa taagagcccgggaaagagtgtatgaattcttgagcgcctggagcaccccccagcgcttcgagtgcgaccaggaggagggc gcaaacacacgtgcctggcggacgtcgctgctgatcgcgctggggacgctgctggccctggtctgtgtcttcgtgatctg cagaaggtatctggtgatgcagagactctttccccgcatccctcacatgaaagaccccatcggtgacagcttccaaaacg acaagctggtggtctgggaggcgggcaaagccggcctggaggagtgtctggtgactgaagtacaggtcgtgcagaaaact tgagactggggttcagggcttgtgggggtctgcctcaatctccctggccgggccaggcgcctgcacagactggctgctgg acctgcgcacgcagcccaggaatggacattcctaacgggtggtgggcatgggagatgcctgtgtaatttcgtccgaagct gccaggaagaagaacagaac (SEQ ID NO: 11909) gatcgttagcttctcctgataaactaattgcctcacattgtcactgcaaatcgacacctattaatgggtctcacctccca actgcttccccctctgttcttcctgctagcatgtgccggcaactttgtccacggacacaagtgcgatatcaccttacagg agatcatcaaaactttgaacagcctcacagagcagaagactctgtgcaccgagttgaccgtaacagacatctttgctgcc tccaagaacacaactgagaaggaaaccttctgcagggctgcgactgtgctccggcagttctacagccaccatgagaagga cactcgctgcctgggtgcgactgcacagcagttccacaggcacaagcagctgatccgattcctgaaacggctcgacagga acctctggggcctggcgggcttgaattcctgtcctgtgaaggaagccaaccagagtacgttggaaaacttcttggaaagg ctaaagacgatcatgagagagaaatattcaaagtgttcgagctgaatattttaatttatgagtttttgatagctttattt tttaagtatttatatatttataactcatcataaaataaagtatatatagaatct (SEQ ID NO: 11910) gaattcaataaaaaacaagcagggcgcgtggtggggcactgactaggagggctgatttgtaagttggtaagactgtagct ctttttcctaattagctgaggatgtgtttaggttccattcaaaaagtgggcattcctggccaggcatggtggctcacacc tgtaatctcagagctttgggagactgaggtaggaggatcacttgagcccaggaatttgagatgagcctaggcaacatagt gagactcttatctctatcaaaaaataaaaataaaaatgagccaggcatggtgcggtggaccacgcacctactgctagggg ggctgaggtgggaggatcattgagcctgggaggttgaggctgcagtgatccctgatcaaacattgcatttcagcctgggt gacagagtgagaccctgtctcagaaaaaaaaaaaaaaagtcattcctgaaacctcagaatagacctaccttgccaagggc ttccttatgggtaaggaccttatggacctgctgggacccaaactaggcctcacctgatacgacctgtccttctcaaaaca ctaaacttgggagaacattgtcccccagtgctggggtaggagagtctgcctgttattctgcctctatgcagagaaggagc cccagatcatcttttccatgacaggacagtttccaagatgccacctgtacttggaagaagccaggttaaaatacttttca agtaaaactttcttgatattactctatctttccccaggaggactgcattacaacaaattcggacacctgtggcctctccc ttctatgcaaagcaaaaagccagcagcagccccaagctgataagattaatctaaagagcaaattatggtgtaatttccta tgctgaaactttgtagttaattttttaaaaaggtttcattttcctattggtctgatttcacaggaacattttacctgttt gtgaggcattttttctcctggaagagaggtgctgattggccccaagtgactgacaatctggtgtaacgaaaatttccaat gtaaactcattttccctcggtttcagcaattttaaatctatatatagagatatctttgtcagcattgcatcgttagcttc tcctgataaactaattgcctcacattgtcactgcaaatcgacacctattaatgggtctcacctcccaactgcttccccct ctgttcttcctgctagcatgtgccggcaactttgtccacggacacaagtgcgatatcaccttacaggagatcatcaaaac tttgaacagcctcacagagcagaaggtgagtacctatctggcaccatctctccagatgttctggtgatgctctcagtatt tctaggcatgaaaacgttaacagctgctagagaagttggaactggtggttggtggcagtccagggcacacagcgaggctt ctccctgccactcttttttctgagggtttgtaggaagtttcctcagttggagggagtgagagctgctcatcaaggacttc tctgtccggttggaggttaactctgtctcttgctctctcatttctgcctggaccaagactctgtgcaccgagttgaccgt aacagacatctttgctgcctccaaggtaagaagccgtcccacggtctgttttagcaaatggggagatccatccccaaatg tctgaacaagaaacttgtctaatggaaaacgagcgggcccaaattaactctaaggtgttagatgttttcaaagaacgaga agtctgatctttactcttaagcatgttttggtctttctggtttcacttgatttagaagacatgtaatagaaagcttacat gctgtagtcctgactcagatcctggtcaaagaaaagccctcttgggttttacttagctttggcatagtgcctggaacgta ggaggcactcaataaatgcctgttgaatgagagaatttttctggcccatacatttctgaaaaaccaaatactctcacaga aacagatattgagatgacaggttgagggagctttcattttgtctaagagacttcctatggcaacagaaaaggtatcgcca gagcccctcctcttccacagcctggccacctaacagccctctggttccggggctgccgtccagagctctcagcttgctct ggccggccgaactcccctccagctcggtctggaaccatcctgctgggcagcgtccagcacatccctgcttcgggctgcct gggcacctcgcctctctgcctcctgtgctgcctcacccccacccctctatctgtagtgggagggagatagatttgacagc tgatagtgcattttctctgacaaacacatgactacagccgtatcaatagttttgtgcatttcagttcctgttttcatgga aacacacggctgagaatgaaagccccaaagcctcaatttcacagtggtctcctaactacctgctttccatgcaaactagg gagatgatatggccaggagtgaagccctgtgtgttgggcagggtcacactccagcacccagaccatagaacagggcccat cctgcttcatgagggaaactgctcttcgggcctttagctggactatctcatttcattagttatcccgggagtccgataca ggatgagattctgaagggcaaatacacactttttttttttttttgagatagggtcttgttctgtcacccaggctggagtg cagtggtgcgatttcagctcatagcagcctccacctcccaggctcaagctatcttcctacctcagcctcccaagtagccg ggacgacaggtgtgcaccaccacgcctggctaatttttgtatttttttgtagagatggagtcttgccattttgcccaggc ttgtctcgaacttctgggctcaagcaatccgtccacσtcggcctctcaaagtgctgggattagccactgcacctgggcaa cagtttatgtgtgtgtgtgtgtgtgtgtgtatatatgtgtgtgtgtgtatatatatgtgtgtatgtatatatgtgtatgt atatgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtataaaatctccaagtccatccaaccgagatggctcctactagaagc caagagtccaccgggttgagcactgggtctctggaggcctgtcggactgctgagaaggctctaacaaagccaagggaagg gccacctcactagaagccaggcctggaggaagggtgagggctgagggctggaggtaagactgcctgtggttttagaccca ggctctgccactgactagctgtgtggctggccttcagacatcttcacagctctctgcacctcagtttccacatgtgaaga tatgaaagtgattctgaaggtgattgcaaggttgattggaatccagctcttgagttagtgcaaagtgttattgtgagatg atataaccacgattaaaagcaagaacaggtgcagagaagcgatgattctaagaaggaggggaccgggttggaaaggatca aaccatccaggatgccgagtctggggcaatccatctgggctgtttctggaagacccccgggtgcaggccaggacactgct gccctcccgtccttaactcccctcttcactcagtcctcactcacctccctctcacacacacaaacatctcctagaataat ccccactgcctgccttcactcttacccgtctcatttgcctcccctgaacttcatcctcctggagttcacgatctcactct tcactcttttcttcccctcgaagattcagcactgcttacttacatgttaagatatttcagaacagtgaaatgttgctatt ttcaaaaacctacaaaggtggtatgcagaggaaaaggtacttctttgtgttcccaaagaaaacatctttccaaaatccag cctattgattttatttcttcgggggaacaagaattttagtatctctaagttgggtagcattctactcttggcagttgctg gaaagaaggcactggtctaggtcctgggcttcacaggtaacacctgtcagggtgtctatgaagtcaaggctgtctgagga acagcaaagtgggaagaagcaagctggctggctgatgaagggtttcttgggtggacaagtagttggagcgatttcctatt taccaaagagagctaaagttcataattctacagagagttccataatgaacctcaaatacctctgttttttgaaggagttt ctcatatacagcactagctgactatcctgggcaggatgggagataatgaatgcagtgccaatcgggctggatttatatgg tcctagtgaggctggtcaagaaccgagttagaactctcacagagtcactgcccacagaagaaatctcccaagtggctgtt tcctgacattcccgggaggcaggcctccttctgagtcactccctaagcagttctgaactgtgaggtcagccaggctgtcc aagtgcactccctgagccactggcagacacactcagcagccagagctagacaggcaggtggtaggagtccagggccacgg cagggatggagtgtcgccccctcgctgcgataccagagcaagtaaaacgttaaggccttgcactaaagctgcccttagga tgcattcttttaaagtttttccatttaatgcagactcttttcaattcttattttatccttgtttcctttagaaagtcctt tgaaaaatatctttagagggttttttcctatactatgtggccatatacgggtcaaaattaagtttaatttccaggctcca agccagcgtttcagaaaaatctcaccaaggtttgtggtaaaagaagcaaagggctgactttttggttttcttgaatctca ctgttccctctgcagcagcatgcatgtctgcccacctccagacacacaggcaccatctgccgccccccatcagcccgtgt cccttccacctcgactcgcctacaaagcccagagaggtctgtttcttggcccccagagcccaaagatactgacacactct tacatttccaactagaatcaggaacgaggagtgactctcagtcagttcattaagtaaatgtctttctaaccgctctgccc atgggacatcacgccccacaggggaaaggggaagcttctgtagcctgggattctggtgcctcagtctgggtctagacttt cctgaaaaaacgttaaaatatgaactgcattcctagaatttagcctacataaataagagatgaacacaaagatttctata gtttactcactgccgcttatttacagaagcaaaaatctgccacgataggggcctgacaaatgacagtaccactgtgcaat gcgtttctacgcagctctcaatcccatgttctctaataccaccgaaggcttaggaaatgcttatggtatatgtaaagagt aaagaagttacaaacagtatcaacagttgacccctattttaaaaagtatttttgaaaagtgtgacgatatttaccaaaat attaacgagcaatagttacctctggctggtgggatgagtgaatgtatttttgttgaatatatgttacctttatagtaaat atatgttatcttgatcatcagaaaaaaaaatatgtaagaacttgaaagctgcttggacagcgctgctgatagaaacccct gagcatcttgtcactgttcttctgattcagagggtctgggtggggcaggggtggtctgagattctgtatttctaagaagc tcccagtgatgtccatgctgctgtccatggaccacactttgagtatcaagggaccagagcatgtcgggggagaggctggg gatagctttctttatctgaactggataaaggaactgggctcaagctaagaaccctctccaggttctgcatctttgttctt cagtgaaaaatgagaggacacaccaggccaggttcagactgagacacaatccctctcctgggttcccaatgacttg ctc ttgtccattcccttctctaaggctaagggccccccaggaagagccatgtggccagaccctcacagttgctggcattccaa ggagattctcactccgcatcattggtccaaaaggccccttacagaagctctgcccaaggctcagatcaatggcacctgct cccagagctcctctgatctcccaggacacctttccctgatctgtgcacttatctcttgctgcctggcaaaatgtcttagc tcctcacttgggccatgtgctgctctcctctcccatggggagagccacacggagagtgctggccaaagcagcagagttca ggccaaaggatgtgcactcatttattcaacaggcatgcaggatttccagggaaagctggattttaaaacctctgggaaca agagcagaacctgactgagagctcatgtgggcacttttcatagcagaatagctcatgaggtatagagacacggacgcaga acgtgggctgtagcgacagatggtcctgcattctagtccccactgtgccttttcctcatgggatgactttattcaggtac cctttcggcaaaatcctccaagagaaaggaaactgggaggttctggggagaaggctgctgcgtttgcaattgggagaggt tgttgacagaggtttatgtctgtggcaagcagccttccttcagtggaatacttgaagacaggtctgtagttgagcaaact cacctccatttgtcctcctggaaagaagaaatcaagaggaaaaatctctctcccatcctccaaatggagctggcacattg ctatctgtggcatttgtctttccagaacacaactgagaaggaaaccttctgcagggctgcgactgtgctccggcagttct acagccaccatgagaaggacactcgctgcctgggtgcgactgcacagcagttccacaggcacaagcagctgatccgattc ctgaaacggctcgacaggaacctctggggcctggcgggcttggtaagctgcactgtattcctggcaagccggccgcgtgg ctcctggtggacagcagcctcacttctaaacactccttaggagctgcagcacccttggtcaacccattcattcattcact cattcaataagtatttgctgaagttccacaagtgctgggtgtggttctaggtgctgaggacgtgtcactaaagacagcag gccgagtccctgttctcatggaatgttctaatgggagagttagaaaaacaaacatgtaaaatgatggccagcagtgatac gtgctacaaagaaaaacatagaaataaagaacataagagtcatgggggagggggctgacttaggagctggtgacattatc tgagcagatatttgaattgagggagcaggccacatgactaactagggagaccattccagggagaaggaggaggtatgcaa aggccttaggatggaaatgaactaacttcctgtatttaaagaccagtaggaaggccagtgtggctggatcagagtgagtg aggggtagtttccaggacagcagatcacacaaggcctttagattccaccacgagtatggagggaacacctgcagagcttt gggcaggacaaagactgtacaatctgatttacgtgatttaaaagggtcagtctggctactgtgtggtaaataggctgaaa gggggaaagcatagaagcaagatggcctgttgggaggctaccacagtaaaccaggctagagatgatggtggcgtggacag aatgaagcaagatggcctgttgggaggctaccacagtaaaccaggctagagatgatggtggcgtggacagaatgaagcaa gatggcctgttgggaggctaccacagtaaaccaggctagagatgatggtggcgtggacaaatggagcagttgaggtgaac agatttgggatatgactaaaaataaaaccagaagatttgctgacagatcggttgtagggggtaagatacaggggaggaaa agatgacctctttgttcctgcccaaacccctctggcgatggtcagtactgtttacagagagatgaaagactggcggcaag gcagggctggaggttcagcagaagatcaagagttcaattttgtacatcgtacatgtaaggtggctcttggatagccaagt gaaggtgttgagaagatggttagaaaagtctggaacttaggggagaggtcagaacttgcaatacaaaaaggagagtcctt agatagatactgctgaaaatctgaatgacagaaagggagagatcaaaggactgagcctgagatcaacacatggaggtcag gagaggaggatccagccaaggggcctgaggaggagtgaccagtgaggcaggagaacatggagagtgggcggtaccccagg aagccggtgaggacactcaaggagggagggttgactgtgtcaaatgtactgaaaggacaggtcaggtgaggaccaagaaa ggcccctgggtttggctgatggaggccatgggtgaggctgatgtaaatggagaggcaggaaggaaagcccagctggagtg ggctcaccgaggatagggtggcgagaggagacaaagaaggaacagtgagggcagacaactctttgaagatgtttagctat aaggctgcagagaaactgagcccacagctgcagggtggttatggagtgagggaagctcttttaaggttgggggtataccc agcatgttaatgcacctgggggaatggtccagtggagcaggaagaactgaagagagcagaaagaggaagaatcattaggg ggcagaagtccttgtagcccagagtggatgttatctaatatcgagtggaggaattaattggctttagaggagaacaagga catgtatcccctctctgggcctatcaccttgtagacaatgggataggtcatgggataggaacttggcacaacacatgttc tctcttttaattctctccattatcttatgaagcaggcaagtaggcaaacaattgtcccaactttacaaaagaaactgaag cttttataaattaagtagtacatcctaagcaatacaattaataaatggtagagctgagattcaaactgaagcagtggcct gggggtagcatctggaatccttcccacctttagggctgctgtgctgcggtgctgctgtttaatggcacagagggccagat gactgaatctctctcagcagtccaggcagtcatgcagaaggcccagtagagcaccgggcaggtctgagccagcatcttca agttccaccctgtgagcaagcacttagctgtgacacacttctcgagagactggactcccccccgcgcaacccacccaaaa gcagataggtaatggtatacagtaaccatttctagaagtgtaagtagtatgcacccaaaataggcaaaacctgctggcct agtgatagagacaactcccagtcaggctagactggaggccttggttttataagtgttcaggtgacaagtgccacagtagg cttgatcaagtagacaggcaggcaagacaaatgcttaccaatgcaagctaatgaaatgtttcttttgcagaattcctgtc ctgtgaaggaagccaaccagagtacgttggaaaacttcttggaaaggctaaagacgatcatgagagagaaatattcaaag tgttcgagctgaatattttaatttatgagtttttgatagctttattttttaagtatttatatatttataactcatcataa aataaagtatatatagaatctaacagcaatggcatttaatgtattggctatgtttacttgacaaatgaaattatggtttg caacttttagggaaatcaatttagtttaccaagagactataaatgctatggagccaaaac (SEQ ID NO: 11911) gatcgttagcttctcctgataaactaattgcctcacattgtcactgcaaatcgacacctattaatgggtctcacctccca actgcttccccctctgttcttcctgctagcatgtgccggcaactttgtccacggacacaagtgcgatat accttacagg agatcatcaaaactttgaacagcctcacagagcagaagactctgtgcaccgagttgaccgtaacagacatctttgctgcc tccaagaacacaactgagaaggaaaccttctgcagggctgcgactgtgctccggcagttctacagccaccatgagaagga cactcgctgcctgggtgcgactgcacagcagttccacaggcacaagcagctgatccgattcctgaaacggctcgacagga acctctggggcctggcgggcttgaattcctgtcctgtgaaggaagccaaccagagtacgttggaaaacttcttggaaagg ctaaagacgatcatgagagagaaatattcaaagtgttcgagctgaatattttaatttatgagtttttgatagctttattt tttaagtatttatatatttataactcatcataaaataaagtatatatagaatctgaattcaataaaaaacaagcagggcg cgtggtggggcactgactaggagggctgatttgtaagttggtaagactgtagctctttttcctaattagctgaggatgtg tttaggttccattcaaaaagtgggcattcctggccaggcatggtggctcacacctgtaatctcagagctttgggagactg aggtaggaggatcacttgagcccaggaatttgagatgagcctaggcaacatagtgagactcttatctctatcaaaaaata aaaataaaaatgagccaggcatggtgcggtggaccacgcacctactgctaggggggctgaggtgggaggatcattgagcc tgggaggttgaggctgcagtgatccctgatcaaacattgcatttcagcctgggtgacagagtgagaccctgtctcagaaa aaaaaaaaaaaagtcattcctgaaacctcagaatagacctaccttgccaagggcttccttatgggtaaggaccttatgga cctgctgggacccaaactaggcctcacctgatacgacctgtccttctcaaaacactaaacttgggagaacattgtccccc agtgctggggtaggagagtctgcctgttattctgcctctatgcagagaaggagccccagatcatcttttccatgacagga cagtttccaagatgccacctgtacttggaagaagccaggttaaaatacttttcaagtaaaactttcttgatattactcta tctttccccaggaggactgcattacaacaaattcggacacctgtggcctctcccttctatgcaaagcaaaaagccagcag cagccccaagctgataagattaatctaaagagcaaattatggtgtaatttcctatgctgaaactttgtagttaatttttt aaaaaggtttcattttcctattggtctgatttcacaggaacattttacctgtttgtgaggcattttttctcctggaagag aggtgctgattggccccaagtgactgacaatctggtgtaacgaaaatttccaatgtaaactcattttccctcggtttcag caattttaaatctatatatagagatatctttgtcagcattgcatcgttagcttctcctgataaactaattgcctcacatt gtcactgcaaatcgacacctattaatgggtctcacctcccaactgcttccccctctgttcttcctgctagcatgtgccgg caactttgtccacggacacaagtgcgata caccttacaggagatcatcaaaactttgaacagcctcacagagcagaagg tgagtacctatctggcaccatctctccagatgttctggtgatgctctcagtatttctaggcatgaaaacgttaacagctg ctagagaagttggaactggtggttggtggcagtccagggcacacagcgaggcttctccctgccactcttttttctgaggg tttgtaggaagtttcctcagttggagggagtgagagctgctcatcaaggacttctctgtccggttggaggttaactctgt ctcttgctctctcatttctgcctggaccaagactctgtgcaccgagttgaccgtaacagacatctttgctgcctccaagg taagaagccgtcccacggtctgttttagcaaatggggagatccatccccaaatgtctgaacaagaaacttgtctaatgga aaacgagcgggcccaaattaactctaaggtgttagatgttttcaaagaacgagaagtctgatctttactcttaagcatgt tttggtctttctggtttcacttgatttagaagacatgtaatagaaagcttacatgctgtagtcctgactcagatcctggt caaagaaaagccctcttgggttttacttagctttggcatagtgcctggaacgtaggaggcactcaataaatgcctgttga atgagagaatttttctggcccatacatttctgaaaaaccaaatactctcacagaaacagatattgagatgacaggttgag ggagctttcattttgtctaagagacttcctatggcaacagaaaaggtatcgccagagcccctcctcttccacagcctggc cacctaacagccctctggttccggggctgccgtccagagctctcagcttgctctggccggccgaactcccctccagctcg gtctggaaccatcctgctgggcagcgtccagcacatccctgcttcgggctgcctgggcacctcgcctctctgcctcctgt gctgcctcacccccacccctctatctgtagtgggagggagatagatttgacagctgatagtgcattttctctgacaaaca catgactacagccgtatcaatagttttgtgcatttcagttcctgttttcatggaaacacacggctgagaatgaaagcccc aaagcctcaatttcacagtggtctcctaactacctgctttccatgcaaactagggagatgatatggccaggagtgaagcc ctgtgtgttgggcagggtcacactccagcacccagaccatagaacagggcccatcctgcttcatgagggaaactgctctt cgggcctttagctggactatctcatttcattagttatcccgggagtccgatacaggatgagattctgaagggcaaataca cactttttttttttttttgagatagggtcttgttctgtcacccaggctggagtgcagtggtgcgatttcagctcatagca gcctccacctcccaggctcaagctatcttcctacctcagcctcccaagtagccgggacgacaggtgtgcaccaccacgcc tggctaatttttgtatttttttgtagagatggagtcttgccattttgcccaggcttgtctcgaacttctgggctcaagca atccgtccacctcggcctctcaaagtgctgggattagccactgcacctgggcaacagtttatgtgtgtgtgtgtgtgtgt gtgtatatatgtgtgtgtgtgtatatatatgtgtgtatgtatatatgtgtatgtatatgtgtgtgtgtgtgtgtgtgtgt gtgtgtgtataaaatctccaagtccatccaaccgagatggctcctactagaagccaagagtccaccgggttgagcactgg gtctctggaggcctgtcggactgctgagaaggctctaacaaagccaagggaagggccacctcactagaagccaggcctgg aggaagggtgagggctgagggctggaggtaagactgcctgtggttttagacccaggctctgccactgactagctgtgtgg ctggccttcagacatcttcacagctctctgcacctcagtttccacatgtgaagatatgaaagtgattctgaaggtgattg caaggttgattggaatccagctcttgagttagtgcaaagtgttattgtgagatgatataaccacgattaaaagcaagaac aggtgcagagaagcgatgattctaagaaggaggggaccgggttggaaaggatcaaaccatccaggatgccgagtctgggg caatccatctgggctgtttctggaagacccccgggtgcaggccaggacactgctgccctcccgtccttaactcccctctt cactcagtcctcactcacctccctctcacacacacaaacatctcctagaataatccccactgcctgccttcactcttacc cgtctcatttgcctcccctgaacttcatcctcctggagttcacgatctcactcttcactcttttcttcccctcgaagatt cagcactgct acttacatgttaagatatttcagaacagtgaaatgttgctattttcaaaaacctacaaaggtggtatgc agaggaaaaggtacttctttgtgttcccaaagaaaacatctttccaaaatccagcctattgattttatttcttcggggga acaagaattttagtatctctaagttgggtagcattc actcttggcagttgctggaaagaaggcactggtctaggtcctg ggcttcacaggtaacacctgtcagggtgtctatgaagtcaaggctgtctgaggaacagcaaagtgggaagaagcaagctg gctggctgatgaagggtttcttgggtggacaagtagttggagcgatttcctatttaccaaagagagctaaagttcataat tctacagagagttccataatgaacctcaaatacctctgttttttgaaggagtttctcatatacagcactagctgactatc ctgggcaggatgggagataatgaatgcagtgccaatcgggctggatttatatggtcctagtgaggctggtcaagaaccga gttagaactctcacagagtcactgcccacagaagaaatctcccaagtggctgtttcctgacattcccgggaggcaggcct ccttctgagtcactccctaagcagttctgaactgtgaggtcagccaggctgtccaagtgcactccctgagccactggcag acacactcagcagccagagctagacaggcaggtggtaggagtccagggccacggcagggatggagtgtcgccccctcgct gcgataccagagcaagtaaaacgttaaggccttgcactaaagctgcccttaggatgcattcttttaaagtttttccattt aatgcagactcttttcaattcttattttatccttgtttcctttagaaagtcctttgaaaaatatctttagagggtttttt cctatactatgtggccatatacgggtcaaaattaagtttaatttccaggctccaagccagcgtttcagaaaaatctcacc aaggtttgtggtaaaagaagcaaagggctgactttttggttttcttgaatctcactgttccctctgcagcagcatgcatg tctgcccacctccagacacacaggcaccatctgccgccccccatcagcccgtgtcccttccacctcgactcgcctacaaa gcccagagaggtctgtttcttggcccccagagcccaaagatactgacacactcttacatttccaactagaatcaggaacg aggagtgactctcagtcagttcattaagtaaatgtctttctaaccgctctgcccatgggacatcacgccccacaggggaa aggggaagcttctgtagcctgggattctggtgcctcagtctgggtctagactttcctgaaaaaacgttaaaatatgaact gcattcctagaatttagcctacataaataagagatgaacacaaagatttctatagtttactcactgccgcttatttacag aagcaaaaatctgccacgataggggcctgacaaatgacagtaccactgtgcaatgcgtttctacgcagctctcaatccca tgttctctaataccaccgaaggcttaggaaatgcttatggtatatgtaaagagtaaagaagttacaaacagtatcaacag ttgacccctattttaaaaagta ttttgaaaagtgtgacgatatttaccaaaatattaacgagcaatagttacctctggc tggtgggatgagtgaatgtatttttgttgaatatatgttacctttatagtaaatatatgttatcttgatca cagaaaaa aaaatatgtaagaacttgaaagctgcttggacagcgctgctgatagaaacccctgagcatcttgtcactgttcttctgat tcagagggtctgggtggggcaggggtggtctgagattctgtatttctaagaagctcccagtgatgtccatgctgctgtcc atggaccacactttgagtatcaagggaccagagcatgtcgggggagaggctggggatagctttctttatctgaactggat aaaggaactgggctcaagctaagaaccctctccaggttctgcatctttgttcttcagtgaaaaatgagaggacacaccag gccaggttcagactgagacacaatccctctcctgggttcccaatgacttgtctcttgtccattcccttctctaaggctaa gggccccccaggaagagccatgtggccagaccctcacagttgctggcattccaaggagattctcactccgcatcattggt ccaaaaggccccttacagaagctctgcccaaggctcagatcaatggcacctgctcccagagctcctctgatctcccagga cacctttccctgatctgtgcacttatctcttgctgcctggcaaaatgtcttagctcctcacttgggccatgtgctgctct cctctcccatggggagagccacacggagagtgctggccaaagcagcagagttcaggccaaaggatgtgcactcatttatt caacaggcatgcaggatttccagggaaagctggattttaaaacctctgggaacaagagcagaacctgactgagagctcat gtgggcacttttcatagcagaatagctcatgaggtatagagacacggacgcagaacgtgggctgtagcgacagatggtcc tgcattctagtccccactgtgccttttcctcatgggatgactttattcaggtaccctttcggcaaaatcctccaagagaa aggaaactgggaggttctggggagaaggctgctgcgtttgcaattgggagaggttgttgacagaggtttatgtctgtggc aagcagccttccttcagtggaatacttgaagacaggtctgtagttgagcaaactcacctccatttgtcctcctggaaaga agaaatcaagaggaaaaatctctctcccatcctccaaatggagctggcacattgctatctgtggcatttgtctttccaga acacaactgagaaggaaaccttctgcagggctgcgactgtgctccggcagttctacagccaccatgagaaggacactcgc tgcctgggtgcgactgcacagcagttccacaggcacaagcagctgatccgattcctgaaacggctcgacaggaacctctg gggcctggcgggcttggtaagctgcactgtattcctggcaagccggccgcgtggctcctggtggacagcagcctcacttc taaacactccttaggagctgcagcacccttggtcaacccattcattcattcactcattcaataagtatttgctgaagttc cacaagtgctgggtgtggttctaggtgctgaggacgtgtcactaaagacagcaggccgagtccctgttctcatggaatgt tctaatgggagagttagaaaaacaaacatgtaaaatgatggccagcagtgatacgtgctacaaagaaaaacatagaaata aagaacataagagtcatgggggagggggctgacttaggagctggtgacattatctgagcagatatttgaattgagggagc aggccacatgactaactagggagaccattccagggagaaggaggaggtatgcaaaggccttaggatggaaatgaactaac ttcctgtatttaaagaccagtaggaaggccagtgtggctggatcagagtgagtgaggggtagtttccaggacagcagatc acacaaggcctttagattccaccacgagtatggagggaacacctgcagagctttgggcaggacaaagactgtacaatctg atttacgtgatttaaaagggtcagtctggctactgtgtggtaaataggctgaaagggggaaagcatagaagcaagatggc ctgttgggaggctaccacagtaaaccaggctagagatgatggtggcgtggacagaatgaagcaagatggcctgttgggag gctaccacagtaaaccaggctagagatgatggtggcgtggacagaatgaagcaagatggcctgttgggaggctaccacag taaaccaggctagagatgatggtggcgtggacaaatggagcagttgaggtgaacagatttgggatatgactaaaaataaa accagaagatttgctgacagatcggttgtagggggtaagatacaggggaggaaaagatgacctctttgttcctgcccaaa cccctctggcgatggtcagtactgtttacagagagatgaaagactggcggcaaggcagggctggaggttcagcagaagat caagagttcaattttgtacatcgtacatgtaaggtggctcttggatagccaagtgaaggtgttgagaagatggttagaaa agtctggaacttaggggagaggtcagaacttgcaatacaaaaaggagagtccttagatagatactgctgaaaatctgaat gacagaaagggagagatcaaaggactgagcctgagatcaacacatggaggtcaggagaggaggatccagccaaggggcct gaggaggagtgaccagtgaggcaggagaacatggagagtgggcggtaccccaggaagccggtgaggacactcaaggaggg agggttgactgtgtcaaatgtactgaaaggacaggtcaggtgaggaccaagaaaggcccctgggtttggctgatggaggc catgggtgaggctgatgtaaatggagaggcaggaaggaaagcccagctggagtgggctcaccgaggatagggtggcgaga ggagacaaagaaggaacagtgagggcagacaactctttgaagatgtttagctataaggctgcagagaaactgagcccaca gctgcagggtggttatggagtgagggaagctcttttaaggttgggggtatacccagcatgttaatgcacctgggggaatg gtccagtggagcaggaagaactgaagagagcagaaagaggaagaatcattagggggcagaagtccttgtagcccagagtg gatgttatctaatatcgagtggaggaattaattggctttagaggagaacaaggacatgtatcccctctctgggcctatca ccttgtagacaatgggataggtcatgggataggaacttggcacaacacatgttctctcttttaattctctccattatctt atgaagcaggcaagtaggcaaacaattgtcccaactttacaaaagaaactgaagcttttataaattaagtagtacatcct aagcaatacaattaataaatggtagagctgagattcaaactgaagcagtggcctgggggtagcatctggaatccttccca cctttagggctgctgtgctgcggtgctgctgtttaatggcacagagggccagatgactgaatctctctcagcagtccagg cagtcatgcagaaggcccagtagagcaccgggcaggtctgagccagcatcttcaagttccaccctgtgagcaagcactta gctgtgacacacttctcgagagactggactcccccccgcgcaacccacccaaaagcagataggtaatggtatacagtaac catttctagaagtgtaagtagtatgcacccaaaataggcaaaacctgctggcctagtgatagagacaactcccagtcagg ctagactggaggccttggttttataagtgttcaggtgacaagtgccacagtaggcttgatcaagtagacaggcaggcaag acaaatgcttaccaatgcaagctaatgaaatgtttcttttgcagaattcctgtcctgtgaaggaagccaaccagagtacg ttggaaaacttcttggaaaggctaaagacgatcatgagagagaaatattcaaagtgttcgagctgaatattttaatttat gagtttttgatagctttattttttaagtatttatatatttataactcatcataaaataaagtatatatagaatctaacag caatggcatttaatgtattggctatgtttacttgacaaatgaaattatggtttgcaacttttagggaaatcaatttagtt taccaagagactataaatgctatggagccaaaac (SEQ ID NO:11912) ggcgaatggagcaggggcgcgcagataattaaagatttacacacagctggaagaaatcatagagaagccgggcgtggtgg ctcatgcctataatcccagcacttttggaggctgaggcgggcagatcacttgagatcaggagttcgagaccagcctggtg ccttggcatctcccaatggggtggctttgctctgggctcctgttccctgtgagctgcctggtcctgctgcaggtggcaag ctctgggaacatgaaggtcttgcaggagcccacctgcgtctccgactacatgagcatctctacttgcgagtggaagatga atggtcccaccaattgcagcaccgagctccgcctgttgtaccagctggtttttctgctctccgaagcccacacgtgtatc cctgagaacaacggaggcgcggggtgcgtgtgccacctgctcatggatgacgtggtcagtgcggataactatacactgga cctgtgggctgggcagcagctgctgtggaagggctccttcaagcccagcgagcatgtgaaacccagggccccaggaaacc tgacagttcacaccaatgtctccgacactctgctgctgacctggagcaacccgtatccccctgacaattacctgtataat catctcacctatgcagtcaacatttggagtgaaaacgacccggcagatttcagaatctataacgtgacctacctagaacc ctccctccgcatcgcagccagcaccctgaagtctgggatttcctacagggcacgggtgagggcctgggctcagtgctata acaccacctggagtgagtggagccccagcaccaagtggcacaactcctacagggagcccttcgagcagcacctcctgctg ggcgtcagcgtttcctgcattgtcatcctggccgtctgcctgttgtgctatgtcagcatcaccaagattaagaaagaatg gtgggatcagattcccaacccagcccgcagccgcctcgtggctataataatccaggatgctcaggggtcacagtgggaga agcggtcccgaggccaggaaccagccaagtgcccacactggaagaattgtcttaccaagctcttgccctgttttctggag cacaacatgaaaagggatgaagatcctcacaaggctgccaaagagatgcctttccagggctctggaaaatcagcatggtg cccagtggagatcagcaagacagtcctctggccagagagcatcagcgtggtgcgatgtgtggagttgtttgaggccccgg tggagtgtgaggaggaggaggaggtagaggaagaaaaagggagcttctgtgcatcgcctgagagcagcagggatgacttc caggagggaagggagggcattgtggcccggctaacagagagcctgttcctggacctgctcggagaggagaatgggggctt ttgccagcaggacatgggggagtcatgccttcttccaccttcgggaagtacgagtgctcacatgccctgggatgagttcc caagtgcagggcccaaggaggcacctccctggggcaaggagcagcctctccacctggagccaagtcctcctgccagcccg acccagagtccagacaacctgacttgcacagagacgcccctcgtcatcgcaggcaaccctgcttaccgcagcttcagcaa ctccctgagccagtcaccgtgtcccagagagctgggtccagacccactgctggccagacacctggaggaagtagaacccg agatgccctgtgtcccccagctctctgagccaaccactgtgccccaacctgagccagaaacctgggagcagatcctccgc cgaaatgtcctccagcatggggcagctgcagcccccgtctcggcccccaccagtggctatcaggagtttgtacatgcggt ggagcagggtggcacccaggccagtgcggtggtgggcttgggtcccccaggagaggctggttacaaggccttctcaagcc tgcttgccagcagtgctgtgtccccagagaaatgtgggtttggggctagcagtggggaagaggggtataagcctttccaa gacctcattcctggctgccctggggaccctgccccagtccctgtccccttgttcacctttggactggacagggagccacc tcgcagtccgcagagctcacatctcccaagcagctccccagagcacctgggtctggagccgggggaaaaggtagaggaca tgccaaagcccccacttccccaggagcaggccacagacccccttgtggacagcctgggcagtggcattgtctactcagcc cttacctgccacctgtgcggccacctgaaacagtgtcatggccaggaggatggtggccagacccctgtcatggccagtcc ttgctgtggctgctgctgtggagacaggtcctcgccccctacaacccccctgagggccccagacccctctccaggtgggg ttccactggaggccagtctgtgtccggcctccctggcaccctcgggcatctcagagaagagtaaatcctcat atccttc catcctgcccctggcaatgctcagagctcaagccagacccccaaaatcgtgaactttgtctccgtgggacccacatacat gagggtctcttaggtgcatgtcctcttgttgctgagtctgcagatgaggactagggcttatccatgcctgggaaatgcca cctcctggaaggcagccaggctggcagatttccaaaagacttgaagaaccatggtatgaaggtgattggccccactgacg ttggcctaacactgggctgcagagactggaccccgcccagcattgggctgggctcgccacatcccatgagagtagagggc actgggtcgccgtgccccacggcaggcccctgcaggaaaactgaggcccttgggcacctcgacttgtgaacgagttgttg gctgctccctccacagcttctgcagcagactgtccctgttgtaactgcccaaggcatgttttgcccaccagatcatggcc cacgtggaggcccacctgcctctgtctcactgaactagaagccgagcctagaaactaacacagccatcaagggaatgact tgggcggccttgggaaatcgatgagaaattgaacttcagggagggtggtcattgcctagaggtgctcattcat taacag agcttccttaggttgatgctggaggcagaatcccggctgtcaaggggtgttcagttaaggggagcaacagaggacatgaa aaattgctatgactaaagcagggacaatttgctgccaaacacccatgcccagctgtatggctgggggctcctcgtatgca tggaacccccagaataaatatgctcagccaccctgtgggccgggcaatccagacagcaggcataaggcaccagttaccct gcatgttggcccagacctcaggtgctagggaaggcgggaaccttgggttgagtaatgctcgtctgtgtgttttagtttca tcacctgttatctgtgtttgctgaggagagtggaacagaaggggtggagttttgtataaataaagtttctttgtctc (SEQ ID NO: 11913) ggatcctaatcaagaccccagtgaacagaactcgaccctgccaaggcttggcagtttccatttcaatcactgtcttccca ccagtattttcaatttcttttaagacagattaatctagccacagtcatagtagaacatagccgatctgaaaaaaacattc ccaatatttatgtattttagcataaaattctgtttagtggtctaccttatactttgttttgcacacatcttttaagagga agttaattttctgattttaagaaatgcaaatgtggggcaatgatgtattaacccaaagattcttcgtaatagaaaatgtt tttaaaggggggaaacagggatttttattattaaaagataaaagtaaatttattttttaagatataaggcattggaaaca tttagtttcacgatatgccattattaggcattctctatctgattgttagaaattattcatttcctcaaagacagacaata aattgactggggacgcagtcttgtactatgcactttctttgccaaaggcaaacgcagaacgtttcagagccatgaggatg cttctgcatttgagtttgctagctcttggagctgcctacgtgtatgccatccccacagaaattcccacaagtgcattggt gaaagagaccttggcactgctttctactcatcgaactctgctgatagccaatgaggtaattttctttatgattcctacag tctgtaaagtgcataggtaatcatttgtgatggttcctttactatatatagagatctgttataaataataagattctgag cacattagtacatgggtgataactacatcaccagcaaacattctgttaaaagttatgaatgctggtgtgctgtaaaaatg attgtatttcctttcctctccagactctgaggattcctgttcctgtacataaaaatgtaagttaaattatgattcagtaa aatgatggcatgaataagtaaatttcctgttttaagctgtaaatcattagttatcattggaactatttaattttctatat tttgttttcatatgggtggctgtgaatgtctgtacttataaatatgaggaatgactttttatcaagtagaatcctttaaa caagtggattaggctctttggtgatgttgttagtttgcctcccaaagagcatcgtgtcagggattctttccagaaggatt ccacactgagtgagaggtgcgtgctagtctccgtgcagttctgactctttctcactctaacgtgtttctgaaagtattag caactcagaattatatttttagaaccatgatcagtagacattaaaatatataacaaatgccctatattaataatttctgc atacttaaataattatgactatatgatggtgttgtatgcatttgaatatgtcctggtcatattaaaatgtaaaatatata gttttattagtctaaatagaataaaactaccagctagaactgtagaaacacattgatatgagtttaatgtataatgcatt acacttccaaaacatttttttccagttacataattaagttatatcctttataaaactcctcagtaatcatataagcttca tct ctttttgaaaattttatcttaatatgtggtggtttgttgcctagaaaacaaacaaaaaactctttggagaagggaa ctcatgtaaataccacaaaacaaagcctaactttgtggaccaaaattgttttaataattattttttaattgatgaattaa aaagtatatatatttattgtgtacaatatgatgttttgaagtatgtatacattgcagaatggacaatggaccaaattttt ataccttgtcttgattatttgcattttaaaaattttcctcatttagcaccaactgtgcactgaagaaatctttcagggaa taggcacactggagagtcaaactgtgcaagggggtactgtggaaagacta tcaaaaacttgtccttaataaagaaatac attgacggccaaaaagtaagttacacacattcaatggaagctatatttgtctggctgtgcctatttctatggaattgaca gtttcctgtaatacctattgtcatttttcttttttcacagaaaaagtgtggagaagaaagacggagagtaaaccaattcc tagactacctgcaagagtttcttggtgtaatgaacaccgagtggataatagaaagttgagactaaactggtttgttgcag ccaaagattttggaggagaaggacattttactgcagtgagaatgagggccaagaaagagtcaggccttaattttcagtat aatttaacttcagagggaaagtaaatatttcaggcatactgacactttgccagaaagcataaaattcttaaaatatattt cagatatcagaatcattgaagtattttcctccaggcaaaattgatatacttttttcttatttaacttaacattctgtaaa atgtctgttaacttaatagtatttatgaaatggttaagaatttggtaaattagtatttatttaatgttatgttgtgttct aataaaacaaaaatagacaactgttcaatttgctgctggcctctgtcttagcaattgaagttagcacagtccattgagta catgcccagtttggaggaagggtctgagcacatgtggctgagcatccccatttctctggagaagtctcaaggttgcaagg cacaccagaggtggaagtgatctagcaggacttagtggggatgtggggagcagggacacaggcaggaggtgaacctggtt ttctctctacagtatatccagaacctgggatggtgcagggtaaatggtagggaataaatgaatgaatgtgctttccaaga ctgattgtagaactaaaatgagttgtaaggcgtcccctggaagaagggcagtgtgggaacctgtaactaggttcctgccc agcctgtgagaagaatttggcagatcaatctcattgccagtatagagaggaagccagaaaccctctctgccaaggcctgc aggggttcttaccccacctgaccctgcaccataacaaaaggaacagagagacactggtagggcagtcccattagaaagac tgagttccgtattcccgggggcagggcagcaccaggccgcacaacactccattctgcctgcttatggctatcagtagcat cactagagattcttctgtttgagaaaacttctcaaggatcc (SEQ ID NO : ) atgcactttctttgccaaaggcaaacgca gaacgtttcagagccatgaggatgcttctgcatttgagtttgctagctcttggagctgcctacgtgtatgccatccccac agaaattcccacaagtgcattggtgaaagagaccttggcactgctttctactca cgaactctgctgatagccaatgaga ctctgaggattcctgttcctgtacataaaaatcaccaactgtgcactgaagaaatctttcagggaataggcacactggag agtcaaactgtgcaagggggtactgtggaaagactattcaaaaacttgtccttaataaagaaatacattgacggccaaaa aaaaaagtgtggagaagaaagacggagagtaaaccaattcctagactacctgcaagagtttcttggtgtaatgaacaccg agtggataatagaaagttgagactaaactggtttgttgcagccaaagattttggaggagaaggacattttactgcagtga gaatgagggccaagaaagagtcaggccttaattttcaatataatttaacttcagagggaaagtaaatatttcaggcatac tgacactttgccagaaagcataaaattcttaaaatatatttcagatatcagaatcattgaagtattttcctccaggcaaa attgatatacttttttcttatttaacttaacattctgtaaaatgtctgttaacttaatagtatttatgaaatggttaaga atttggtaaattagtatttatttaatgttatgttgtgttctaataaaacaaaaatagacaactgttc (SEQ ID NO: 11915) ggatcctaatcaagaccccagtgaacagaactcgaccctgccaaggcttggcagtttccatttcaatcactgtcttccca ccagtattttcaatttcttttaagacagattaatctagccacagtcatagtagaacatagccgatctgaaaaaaacattc ccaatatttatgtattttagcataaaattctgtttagtggtctaccttatactttgttttgcacacatcttttaagagga agttaattttctgattttaagaaatgcaaatgtggggcaatgatgtattaacccaaagattcttcgtaatagaaaatgtt tttaaaggggggaaacagggatttttattattaaaagataaaagtaaatttattttttaagatataaggcattggaaaca tttagtttcacgatatgccattattaggcattctctatctgattgttagaaattattcatttcctcaaagacagacaata aattgactggggacgcagtcttgtactatgcactttctttgccaaaggcaaacgcagaacgtttcagagccatgaggatg cttctgcatttgagtttgctagctcttggagctgcctacgtgtatgccatccccacagaaattcccacaagtgcattggt gaaagagaccttggcactgctttctactcatcgaactctgctgatagccaatgaggtaattttctttatgattcctacag tctgtaaagtgcataggtaatcatttgtgatggttcctttactatatatagagatctgt ataaataataagattctgag cacattagtacatgggtgataactacatcaccagcaaacattctgttaaaagttatgaatgctggtgtgctgtaaaaatg attgtatttcctttcctctccagactctgaggattcctgttcctgtacataaaaatgtaagttaaattatgattcagtaa aatgatggcatgaataagtaaatttcctgttttaagctgtaaatcattagttatcattggaactatttaattttctatat tttgttttcatatgggtggctgtgaatgtctgtacttataaatatgaggaatgactttttatcaagtagaatcctttaaa caagtggattaggctctttggtgatgttgttagtttgcctcccaaagagcatcgtgtcagggattctttccagaaggatt ccacactgagtgagaggtgcgtgctagtctccgtgcagttctgactctttctcactctaacgtgtttctgaaagtattag caactcagaattatatttttagaaccatgatcagtagacattaaaatatataacaaatgccctatattaataatttctgc atacttaaataattatgactatatgatggtgttgtatgcatttgaatatgtcctggtcatattaaaatgtaaaatatata gttttattagtctaaatagaataaaactaccagctagaactgtagaaacacattgatatgagtttaatgtataatgcatt acacttccaaaacatttttttccagttacataattaagttatatcctttataaaactcctcagtaatcatataagcttca tctactttttgaaaattttatcttaatatgtggtggtttgttgcctagaaaacaaacaaaaaactctttggagaagggaa ctcatgtaaataccacaaaacaaagcctaactttgtggaccaaaattgttttaataattattttttaattgatgaattaa aaagtatatatatttattgtgtacaatatgatgttttgaagtatgtatacattgcagaatggacaatggaccaaattttt ataccttgtcttgattatttgcattttaaaaattttcctcatttagcaccaactgtgcactgaagaaatctttcagggaa taggcacactggagagtcaaactgtgcaagggggtactgtggaaagactattcaaaaacttgtccttaataaagaaatac attgacggccaaaaagtaagttacacacattcaatggaagctatatttgtctggctgtgcctatttctatggaattgaca gtttcctgtaatacctattgtcatttttcttttttcacagaaaaagtgtggagaagaaagacggagagtaaaccaattcc tagactacctgcaagagtttcttggtgtaatgaacaccgagtggataatagaaagttgagactaaactggtttgttgcag ccaaagattttggaggagaaggacattttactgcagtgagaatgagggccaagaaagagtcaggccttaattttcagtat aatttaacttcagagggaaagtaaatatttcaggcatactgacactttgccagaaagcataaaattcttaaaatatattt cagatatcagaatcattgaagtattttcctccaggcaaaattgatatacttttttcttatttaacttaacattctgtaaa atgtctgttaacttaatagtatttatgaaatggttaagaatttggtaaattagtatttatttaatgttatgttgtgttct aataaaacaaaaatagacaactgttcaatttgctgctggcctctgtcttagcaattgaagttagcacagtccattgagta catgcccagtttggaggaagggtctgagcacatgtggctgagcatccccatttctctggagaagtctcaaggttgcaagg cacaccagaggtggaagtgatctagcaggacttagtggggatgtggggagcagggacacaggcaggaggtgaacctggtt ttctctctacagtatatccagaacctgggatggtgcagggtaaatggtagggaataaatgaatgaatgtgctttccaaga ctgattgtagaactaaaatgagttgtaaggcgtcccctggaagaagggcagtgtgggaacctgtaactaggttcctgccc agcctgtgagaagaatttggcagatcaatctcattgccagtatagagaggaagccagaaaccctctctgccaaggcctgc aggggttcttaccccacctgaccctgcaccataacaaaaggaacagagagacactggtagggcagtcccattagaaagac tgagttccgtattcccgggggcagggcagcaccaggccgcacaacactccattctgcctgcttatggctatcagtagcat cactagagattcttctgtttgagaaaacttctcaaggatccatgcactttctttgccaaaggcaaacgcagaacgtttca gagccatgaggatgcttctgcatttgagtttgctagctcttggagctgcctacgtgtatgccatccccacagaaattccc acaagtgcattggtgaaagagaccttggcactgctttctactcatcgaactctgctgatagccaatgagactctgaggat tcctgttcctgtacataaaaatcaccaactgtgcactgaagaaatctttcagggaataggcacactggagagtcaaactg tgcaagggggtactgtggaaagactattcaaaaacttgtccttaataaagaaatacattgacggccaaaaaaaaaagtgt ggagaagaaagacggagagtaaaccaattcctagactacctgcaagagtttcttggtgtaatgaacaccgagtggataat agaaagttgagactaaactggtttgttgcagccaaagattttggaggagaaggacattttactgcagtgagaatgagggc caagaaagagtcaggccttaattttcaatataatttaacttcagagggaaagtaaatatttcaggcatactgacactttg ccagaaagcataaaattcttaaaatatatttcagatatcagaatcattgaagtattttcctccaggcaaaattgatatac ttttttcttatttaacttaacattctgtaaaatgtctgttaacttaatagtatttatgaaatggttaagaatttggtaaa ttagtatttatttaatgttatgttgtgttctaataaaacaaaaatagacaactgttc (SEQ ID NO:11916) tagatgctggggttgcagccacgagcatagacacgacagacacggtcctcgccatcttctgttgagtactggtcggaaca agaggatcgtctgtagacaggatatgatcatcgtggcgcatgtattactcatccttttgggggccactgagatactgcaa gctgacttacttcctgatgaaaagatttcacttctcccacctgtcaatttcaccattaaagttactggtttggctcaagt tcttttacaatggaaaccaaatcctgatcaagagcaaaggaatgttaatctagaatatcaagtgaaaataaacgctccaa aagaagatgactatgaaaccagaatcactgaaagcaaatgtgtaaccatcctccacaaaggcttttcagcaagtgtgcgg accatcctgcagaacgaccactcactactggccagcagctgggcttctgctgaacttcatgccccaccagggtctcctgg aacctcaattgtgaatttaacttgcaccacaaacactacagaagacaattattcacgtttaaggtcataccaagtttccc ttcactgcacctggcttgttggcacagatgcccctgaggacacgcagtattttctctactataggtatggctcttggact gaagaatgccaagaatacagcaaagacacactggggagaaatatcgcatgctggtttcccaggacttttatcctcagcaa agggcgtgactggcttgcggtgcttgttaacggctccagcaagcactctgctatcaggccctttgatcagctgtttgccc ttcacgccattgatcaaataaatcctccactgaatgtcacagcagagattgaaggaactcgtctctctatccaatgggag aaaccagtgtctgcttttccaatccattgctttgattatgaagtaaaaatacacaatacaaggaatggatatttgcagat agaaaaattgatgaccaatgcattcatctcaataattgatgatctttctaagtacgatgttcaagtgagagcagcagtga gctccatgtgcagagaggcagggctctggagtgagtggagccaacctatttatgtgggaaatgatgaacacaagcccttg agagagtggtttgtcattgtgattatggcaaccatctgcttcatcttgttaattctctcgcttatctgtaaaatatgtca tttatggatcaagttgtttccaccaattccagcaccaaaaagtaatatcaaagatctctttgtaaccactaactatgaga aagctggaatttaaattcaagcatgttttaacttttggtttaaggtacttgggtgtacctggcagtgttgtaagctcttt acattaattaattaactctctaggtactgttatct cattttataaacaaggcagctgaagttgagagaaataagtaacc tgtcctaggtcacacaattaggaaatgacagatctggcagtctatttccaggcagtctatttccacgaggtcatgagtgc gaaagagggactaggggaagaatgattaactccagggagctgacttttctagtgtgcttacctgttttgcatctctcaag gatgtgccatgaagctgtagccaggtggaattgtaccacagccctgacatgaacacctgatggcagctgctgggttggag cctagacaaaaacatgaagaaccatggctgctgcctgagcccatcgtgctgtaattatagaaaaccttctaagggaagaa tatgctgatatttttcagataagtaccccttttataaaaatcctccaagttagccctcgattttccatgtaaggaaacag aggctttgagataatgtctgtctcctaagggacaaagccaggacttgatcctgtcttaaaaatgcaaaatgtagtacttc ttccatcaaaggtagacatgcactaagggacaggttttggcttggtatcagaatacatttttaaaagctgtgtaagaatt gaacgggctgtactagggggtata (SEQ ID NO: 11917) gatctttctaagtacgatgttcaagtgagagcagcagtgagctccatgtgcagagaggcagggctctggagtgagtggag ccaacctatttatgtgggaaatgatgaacacaagcccttgagagagtggtttgtcattgtgattatggcaaccatctgct tcatcttgttaattctctcgcttatctgtaaaatatgtcatttatggatcaagttgtttccaccaattccagcaccaaaa agtaa atcaaagatctctttgtaaccactaactatgaggtcctctgcattttca atacatcttagattcggctgacaa ttttctacaaaaaaagaaagctgggtccagtgagacggaaattgaag catctgttatatagagaagcctggagttgaga ccctggaggattctgtgttttgactgtcactttggcatcctctgatgaactcacacatgcctcagtgcctcagtgaaaag aacagggatgctggctcttggctaagaggtgttcagaatttaggcaacactcaatttacctgcgaagcaatacacccaga cacaccagtcttgtatctcttaaaagtatggatgcttcatccaaatcgcctcacctacagcagggaagttgactcatcca agcattttgccatgttttttctccccatgccgtacagggtagcacctcctcacctgccaatctttgcaatttgcttgact cacctcagacttttcattcacaacagacagcttttaaggctaacgtccagctgtatttacttctggctgtgcccgtttgg ctgtttaagctgccaattgtagcactcagctaccatctgaggaagaaagcattttgcatcagcctggagtgaaccatgaa cttggattcaagactgtcttttctatagcaagtgagagccacaaattcctc (SEQ ID NO: 11918) ccgctgcttctcatcgcatggccaccgcatttctcaggccaggcacattgagcattggtcctgtgcctgacgctatgcta gatgctggggttgcagccacgagcatagacacgacagacacggtcctcgccatcttctgttgagtactggtcggaacaag aggatcgtctgtagacaggctacagattgttttagattgaagtttcctgtcatgttcactcatctttaaatcctca agt aaaaaggatatgatcatcgtggcgcatgtattactcatccttttgggggccactgagatactgcaagctgacttacttcc tgatgaaaagatttcacttctcccacctgtcaatttcaccattaaagttactggtttggctcaagttcttttacaatgga aaccaaatcctgatcaagagcaaaggaatgttaatctagaatatcaagtgaaaataaacgctccaaaagaagatgactat gaaaccagaatcactgaaagcaaatgtgtaaccatcctccacaaaggcttttcagcaagtgtgcggaccatcctgcagaa cgaccactcactactggccagcagctgggcttctgctgaacttcatgccccaccagggtctcctggaacctcaattgtga atttaacttgcaccacaaacactacagaagacaattattcacgtttaaggtcataccaagtttcccttcactgcacctgg cttgttggcacagatgcccctgaggacacgcagtattttctctactataggtatggctcttggactgaagaatgccaaga atacagcaaagacacactggggagaaatatcgcatgctggtttcccaggacttttatcctcagcaaagggcgtgactggc tttcggtgcttgttaacggctccagcaagcactctgctatcaggccctttgatcagctgtttgcccttcacgccattgat caaataaatcctccactgaatgtcacagcagagattgaaggaactcgtctctctatccaatgggagaaaccagtgtctgc ttttccaatccattgctttgattatgaagtaaaaatacacaatacaaggaatggatatttgcagatagaaaaattgatga ccaatgcattcatctcaataattgatgatctttctaagtacgatgttcaagtgagagcagcagtgagctccatgtgcaga gaggcagggctctggagtgagtggagccaacctatttatgtggggttctcaagataaaggagataacatccagctttcct gccccacaccgtatctgaaataaaaacaacagcagggatagcagatt (SEQ ID NO: 11919) ccgctgcttctcatcgcatggccaccgcatttctcaggccaggcacattgagcattggtcctgtgcctgacgctatgcta gatgctggggttgcagccacgagcatagacacgacagacacggtcctcgccatcttctgttgagtactggtcggaacaag aggatcgtctgtagacaggctacagattgttttagattgaagtttcctgtcatgttcactcatctttaaatcctcatagt aaaaaggatatgatcatcgtggcgcatgtattactcatccttttgggggccactgagatactgcaagctgacttacttcc tgatgaaaagatttcacttctcccacctgtcaatttcaccattaaagttactggtttggctcaagttcttttacaatgga aaccaaatcctgatcaagagcaaaggaatgttaatctagaatatcaagtgaaaataaacgctccaaaagaagatgactat gaaaccagaatcactgaaagcaaatgtgtaaccatcctccacaaaggcttttcagcaagtgtgcggaccatcctgcagaa cgaccactcactactggccagcagctgggcttctgctgaacttcatgccccaccagggtctcctggaacctcaattgtga atttaacttgcaccacaaacactacagaagacaattattcacgtttaaggtcataccaagtttcccttcactgcacctgg cttgttggcacagatgcccctgaggacacgcagtattttctctactataggtatggctcttggactgaagaatgccaaga atacagcaaagacacactggggagaaatatcgcatgctggtttcccaggacttttatcctcagcaaagggcgtgactggc tttcggtgcttgttaacggctccagcaagcactctgctatcaggccctttgatcagctgtttgcccttcacgccattgat caaataaatcctccactgaatgtcacagcagagattgaaggaactcgtctctctatccaatgggagaaaccagtgtctgc ttttccaatccattgctttgattatgaagtaaaaatacacaatacaaggaatggatatttgcagatagaaaaattgatga ccaatgcattcatctcaataattgatgatctttctaagtacgatgttcaagtgagagcagcagtgagctccatgtgcaga gaggcagggctctggagtgagtggagccaacctatttatgtgggtaagtagcttatgtttattttacattggcagccttc cttgtgatcaaaaaaggtaatcccagaaacgtacccgttcactcgtgggtcttaaaatggtttcatatctctattgtgac taattttctctcggtctactgccttttcaatcaggaatagatttgccatgaagccagtgaagtttttaagtgtctaggct tctcattagtgccaactctcctagacctggtgcctgttttttttccaagttttgtttctacttctatccattttttaaat taaactttttattttgaaataattatcacactcacaagctgtgggaagaaataatagagatcctgtgtctctttcatcca gttttcctcaagggtaacatcttacaaaactatagtacaatagtggaatagaatatttggtgtt (SEQ ID NO: 11920) ccgctgcttctcatcgcatggccaccgcatttctcaggccaggcacattgagcattggtcctgtgcctgacgctatgcta gatgctggggttgcagccacgagcatagacacgacagacacggtcctcgccatcttctgttgagtactggtcggaacaag aggatcgtctgtagacaggctacagattgttttagattgaagtttcctgtcatgttcactcatctttaaatcctcatagt aaaaaggatatgatcatcgtggcgcatgtattactcatccttttgggggccactgagatactgcaagctgacttacttcc tgatgaaaagatttcacttctcccacctgtcaatttcaccattaaagttactggtttggctcaagttcttttacaatgga aaccaaatcctgatcaagagcaaaggaatgttaatctagaatatcaagtgaaaataaacgctccaaaagaagatgactat gaaaccagaatcactgaaagcaaatgtgtaaccatcctccacaaaggcttttcagcaagtgtgcggaccatcctgcagaa cgaccactcactactggccagcagctgggcttctgctgaacttcatgccccaccagggtctcctggaacctcaattgtga atttaacttgcaccacaaacactacagaagacaattattcacgtttaaggtcataccaagtttcccttcactgcacctgg cttgttggcacagatgcccctgaggacacgcagtattttctctactataggtatggctcttggactgaagaatgccaaga atacagcaaagacacactggggagaaatatcgcatgctggtttcccaggacttttatcctcagcaaagggcgtgactggc tttcggtgcttgttaacggctccagcaagcactctgctatcaggccctttgatcagctgtttgcccttcacgccattgat caaataaatcctccactgaatgtcacagcagagattgaaggaactcgtctctctatccaatgggagaaaccagtgtctgc ttttccaatccattgctttgattatgaagtaaaaatacacaatacaaggaatggatatttgcagatagaaaaattgatga ccaatgcattcatctcaataattgatgatctttctaagtacgatgttcaagtgagagcagcagtgagctccatgtgcaga gaggcagggctctggagtgagtggagccaacctatttatgtgggaaatgatgaacacaagcccttgagagagtggtttgt cattgtgattatggcaaccatctgcttcatcttgttaattctctcgcttatctgtaaaatatgtcatttatggatcaagt tgtttccaccaattccagcaccaaaaagtaatatcaaagatctctttgtaaccactaactatgagaaagctgggtccagt gagacggaaattgaagtcatctgttatatagagaagcctggagttgagaccctggaggattctgtgttttgactgtcact ttggcatcctctgatgaactcacacatgcctcagtgcctcagtgaaaagaacagggatgctggctcttggctaagaggtg ttcagaatttaggcaacactcaatttacctgcgaagcaatacacccagacacaccagtcttgtatctcttaaaagtatgg atgcttcatccaaatcgcctcacctacagcagggaagttgactcatccaagcattttgccatgttttttctccccatgcc gtacagggtagcacctcctcacctgccaatctttgcaatttgcttgactcacctcagactttcattcacaacagacagct tttaaggctaacgtccagctgtatttacttctggctgtgccgtttggctgtttaagctgccaattgtagcactcagctac catctgaggaagaaagcattttgcatcagcctggagtgaaccatgaacttggattcaagactgtcttttctatagcaa (SEQ ID NO : 11921) gtcttttgaaaggatctgccgctgcttctcatcgcatggccaccgcatttctcaggccaggcacattgagcattggtcct gtgcctgacgctatgctagatgctggggttgcagccacgagcatagacacgacagacacggtcctcgccatcttctgttg agtactggtcggaacaagaggatcgtctgtagacaggatatgatcatcgtggcgcatgtattactcatccttttgggggc cactgagatactgcaagctgacttacttcctgatgaaaagatttcacttctcccacctgtcaatttcaccattaaagtta ctggtttggctcaagttcttttacaatggaaaccaaatcctgatcaagagcaaaggaatgttaatctagaatatcaagtg aaaataaacgctccaaaagaagatgactatgaaaccagaatcactgaaagcaaatgtgtaaccatcctccacaaaggctt ttcagcaagtgtgcggaccatcctgcagaacgaccactcactactggccagcagctgggcttctgctgaacttcatgccc caccagggtctcctggaacctcaattgtgaatttaacttgcaccacaaacactacagaagacaattattcacgtttaagg tcataccaagtttcccttcactgσacctggcttgttggcacagatgcccctgaggacacgcagtattttctctactatag gtatggctcttggactgaagaatgccaagaatacagcaaagacacactggggagaaatatcgcatgctggtttcccagga ctttt tcctcagcaaagggcgtgactggcttgcggtgcttgttaacggctccagcaagcactctgctatcaggcccttt ga cagctgtttgcccttcacgccattgatcaaataaatcctccactgaatgtcacagcagagattgaaggaactcgtct ctctatccaatgggagaaaccagtgtctgcttttccaatccattgctttgattatgaagtaaaaatacacaatacaagga atggatatttgcagatagaaaaattgatgaccaatgcattcatctcaataattgatgatctttctaagtacgatgttcaa gtgagagcagcagtgagctccatgtgcagagaggcagggctctggagtgagtggagccaacctatttatgtgggtaagta gcttatgtttattttacattggcagccttccttgtgatcaaaaaaggtaatcccagaaacgtacccgttcactcgtgggt cttaaaatggtttcatatctctattgtgactaattttctctcggtctactgccttttcaatcaggaatagatttgccatg aagccagtgaagtttttaagtgtctaggcttctcattagcgccac (SEQ ID NO: 11922) cggtcctcgccatcttctgttgagtactggtcggaacaagaggatcgtctgtagacaggatatgatcatcgtggcgcatg tattactcatccttttgggggccactgagatactgcaagctgacttacttcctgatgaaaagatttcacttctcccacct gtcaatttcaccattaaagttactggtttggctcaagttcttttacaatggaaaccaaatcctgatcaagagcaaaggaa tgttaatctagaatatcaagtgaaaataaacgctccaaaagaagatgactatgaaaccagaatcactgaaagcaaatgtg taaccatcctccacaaaggcttttcagcaagtgtgcggaccatcctgcagaacgaccactcactactggccagcagctgg gcttctgctgaacttcatgccccaccagggtctcctggaacctcagttgtgaatttaacttgcaccacaaacactacaga agacaattattcacgtttaaggtcataccaagtttcccttcactgcacctggcttgttggcacagatgcccctgaggaca cgcagtattttctctactataggtatggctcttggactgaagaatgccaagaatacagcaaagacacactggggagaaat atcgcatgctggtttcccaggacttttatcctcagcaaagggcgtgactggcttgcggtgcttgttaacggctccagcaa gcactctgctatcaggccctttgatcagctgtttgcccttcacgccattgatcaaataaatcctccactgaatgtcacag cagagattgaaggaactcgtctctctatccaatgggagaaaccagtgtctgcttttccaatccattgctttgattatgaa gtaaaaatacacaatacaaggaatggatatttgcagatagaaaaattgatgaccaatgcattcatctcaataattgatga tctttctaagtacgatgttcaagtgagagcagcagtgagctccatgtgcagagaggcagggctctggagtgagtggagcc aacctatttatgtgggaaatgatgaacacaagcccttgagagagtggtttgtcattgtgattatggcaaccatctgcttc atcttgttaattctctcgcttatctgtaaaatatgtcatttatggatcaagttgtttccaccaattccagcaccaaaaag taatatcaaagatctctttgtaaccactaactatgagaaagctgggtccagtgagacggaaattgaagtcatctgttata tagagaagcctggagttgagaccctggaggattctgtgttttgactgtcactttggcatcctctgatgaactcacacatg cctcagtgcctcagtgaaaagaacagggatgctggctcttggctaagaggtgttcagaatttaggcaacactcaatttac ctgcgaagcaatacacccagacacaccagtcttgtatctcttaaaagtatggatgcttcatccaaatcgcctcacctaca gcagggaagttgactcatccaagcattttgccatgttttttctccccatgccgtacagggtagcacctcctcacctgcca atctttgcaatttgcttgactcacctcagacttttcattcacaacagacagcttttaaggctaacgtccagctgtattta cttctggctgtgcccgtttggctgtttaagctgccaattgtagcactcagctaccatctgaggaagaaagcattttgcat cagcctggagtgaatcatgaacttggattcaagactgtcttttctatagcaagtgagagccacaaattcctcacccccct acattctagaatgatctttttctaggtagattgtgtatgtgtgtgtatgagagagagagagagagagagagagagagaga gagaaattatctcaagctccagaggcctgatccaggatacatcatttgaaaccaactaatttaaaagcataatagagcta atatat (SEQ ID NO: 11923) tagatgctggggttgcagccacgagcatagacacgacagacacggtcctcgccatcttctgttgagtactggtcggaaca agaggatcgtctgtagacaggatatgatcatcgtggcgcatgtattactcatccttttgggggccactgagatactgcaa gctgacttacttcctgatgaaaagatttcacttctcccacctgtcaatttcaccattaaagttactggtttggctcaagt tcttttacaatggaaaccaaatcctgatcaagagcaaaggaatgttaatctagaatatcaagtgaaaataaacgctccaa aagaagatgactatgaaaccagaatcactgaaagcaaatgtgtaaccatcctccacaaaggcttttcagcaagtgtgcgg accatcctgcagaacgaccactcactactggccagcagctgggcttctgctgaacttcatgccccaccagggtctcctgg aacctcaattgtgaatttaacttgcaccacaaacactacagaagacaattattcacgtttaaggtcataccaagtt ccc ttcactgcacctggcttgttggcacagatgcccctgaggacacgcagtattttctctactataggtatggctcttggact gaagaatgccaagaatacagcaaagacacactggggagaaatatcgcatgctggtttcccaggacttt a cctcagcaa agggcgtgactggcttgcggtgcttgttaacggctccagcaagcactctgctatcaggccctttgatcagctgtttgccc ttcacgccattgatcaaataaatcctccactgaatgtcacagcagagattgaaggaactcgtctctctatccaatgggag aaaccagtgtctgcttttccaatccattgctttgattatgaagtaaaaatacacaatacaaggaatggatatttgcagat agaaaaattgatgaccaatgcattcatctcaataattgatgatctttctaagtacgatgttcaagtgagagcagcagtga gctccatgtgcagagaggcagggctctggagtgagtggagccaacctatttatgtgggaaatgatgaacacaagcccttg agagagtggtttgtcattgtgattatggcaaccatctgct catcttgttaattctctcgcttatctgtaaaatatgtca tttatggatcaagttgtttccaccaattccagcaccaaaaagtaatatcaaagatctctttgtaaccactaactatgaga aagctggaatttaaattcaagcatgttttaacttttggtttaaggtacttgggtgtacctggcagtgttgtaagctcttt acattaattaattaactctctaggtactgttatcttcattttataaacaaggcagctgaagttgagagaaataagtaacc tgtcctaggtcacacaattaggaaatgacagatctggcagtctatttccaggcagtctatttccacgaggtcatgagtgc gaaagagggactaggggaagaatgattaactccagggagctgacttttctagtgtgcttacctgttttgcatctctcaag gatgtgccatgaagctgtagccaggtggaattgtaccacagccctgacatgaacacctgatggcagctgctgggttggag cctagacaaaaacatgaagaaccatggctgctgcctgagcccatcgtgctgtaattatagaaaaccttctaagggaagaa tatgctgatatttttcagataagtaccccttttataaaaatcctccaagttagccctcgattttccatgtaaggaaacag aggctttgagataatgtctgtctcctaagggacaaagccaggacttgatcctgtcttaaaaatgcaaaatgtagtacttc ttccatcaaaggtagacatgcactaagggacaggttttggcttggtatcagaatacatttttaaaagctgtgtaagaatt gaacgggctgtactagggggtatagatctttctaagtacgatgttcaagtgagagcagcagtgagctccatgtgcagaga ggcagggctctggagtgagtggagccaacctatttatgtgggaaatgatgaacacaagcccttgagagagtggtttgtca ttgtgattatggcaaccatctgcttcatcttgttaattctctcgcttatctgtaaaatatgtcatttatggatcaagttg tttccaccaattccagcaccaaaaagtaatatcaaagatctctttgtaaccactaactatgaggtcctctgcattttcat atacatcttagattcggctgacaattttctacaaaaaaagaaagctgggtccagtgagacggaaattgaagtcatctgtt atatagagaagcctggagttgagaccctggaggattctgtgttttgactgtcactttggcatcctctgatgaactcacac atgcctcagtgcctcagtgaaaagaacagggatgctggctcttggctaagaggtgttcagaatttaggcaacactcaatt tacctgcgaagcaatacacccagacacaccagtcttgtatctcttaaaagtatggatgcttcatccaaatcgcctcacct acagcagggaagttgactcatccaagcattttgccatgttttttctccccatgccgtacagggtagcacctcctcacctg ccaatctttgcaatttgcttgactcacctcagacttttcattcacaacagacagcttttaaggctaacgtccagctgtat ttacttctggctgtgcccgtttggctgtttaagctgccaattgtagcactcagctaccatctgaggaagaaagcattttg catcagcctggagtgaaccatgaacttggattcaagactgtcttttctatagcaagtgagagccacaaattcctcccgct gcttctcatcgcatggccaccgcatttctcaggccaggcacattgagcattggtcctgtgcctgacgctatgctagatgc tggggttgcagccacgagcatagacacgacagacacggtcctcgccatcttctgttgagtactggtcggaacaagaggat cgtctgtagacaggctacagattgttttagattgaagtttcctgtcatgttcactcatctttaaatcctcatagtaaaaa ggatatgatcatcgtggcgcatgtattactcatccttttgggggccactgagatactgcaagctgacttacttcctgatg aaaagatttcacttctcccacctgtcaatttcaccattaaagttactggtttggctcaagttcttttacaatggaaacca aatcctgatcaagagcaaaggaatgttaatctagaatatcaagtgaaaataaacgctccaaaagaagatgactatgaaac cagaatcactgaaagcaaatgtgtaaccatcctccacaaaggcttttcagcaagtgtgcggaccatcctgcagaacgacc actcactactggccagcagctgggcttctgctgaacttcatgccccaccagggtctcctggaacctcaattgtgaattta acttgcaccacaaacactacagaagacaattattcacgtttaaggtcataccaagtttcccttcactgcacctggcttgt tggcacagatgcccctgaggacacgcagtattttctctactataggtatggctcttggactgaagaatgccaagaataca gcaaagacacactggggagaaatatcgcatgctggtttcccaggacttttatcctcagcaaagggcgtgactggctttcg gtgcttgttaacggctccagcaagcactctgctatcaggccctttgatcagctgtttgcccttcacgccattgatcaaat aaatcctccactgaatgtcacagcagagattgaaggaactcgtctctctatccaatgggagaaaccagtgtctgcttttc caatccattgctttgattatgaagtaaaaatacacaatacaaggaatggatatttgcagatagaaaaattgatgaccaat gcattcatctcaataattgatgatctttctaagtacgatgttcaagtgagagcagcagtgagctccatgtgcagagaggc agggctctggagtgagtggagccaacctatttatgtggggttctcaagataaaggagataacatccagctttcctgcccc acaccgtatctgaaataaaaacaacagcagggatagcagattccgctgcttctcatcgcatggccaccgcatttctcagg ccaggcacattgagcattggtcctgtgcctgacgctatgctagatgctggggttgcagccacgagcatagacacgacaga cacggtcctcgccatcttctgttgagtactggtcggaacaagaggatcgtctgtagacaggctacagattgttttagatt gaagtttcctgtcatgttcactcatctttaaatcctcatagtaaaaaggatatgatcatcgtggcgcatgtattactcat ccttttgggggccactgagatactgcaagctgacttacttcctgatgaaaagatttcacttctcccacctgtcaatttca ccattaaagttactggtttggctcaagttcttttacaatggaaaccaaatcctgatcaagagcaaaggaatgttaa cta gaatatcaagtgaaaataaacgctccaaaagaagatgactatgaaaccagaatcactgaaagcaaatgtgtaaccatcct ccacaaaggcttttcagcaagtgtgcggaccatcctgcagaacgaccactcactactggccagcagctgggcttctgctg aacttcatgccccaccagggtctcctggaacctcaattgtgaatttaacttgcaccacaaacactacagaagacaattat tcacgtttaaggtcataccaagtttcccttcactgcacctggcttgttggcacagatgcccctgaggacacgcagtattt tctctactataggtatggctcttggactgaagaatgccaagaatacagcaaagacacactggggagaaatatcgcatgct ggtttcccaggacttttatcctcagcaaagggcgtgactggctttcggtgcttgttaacggctccagcaagcactctgct atcaggccctttgatcagctgtttgcccttcacgccattgatcaaataaatcctccactgaatgtcacagcagagattga aggaactcgtctctctatccaatgggagaaaccagtgtctgcttttccaatccattgctttgattatgaagtaaaaatac acaatacaaggaatggatatttgcagatagaaaaattgatgaccaatgcattcatctcaataattgatgatctttctaag tacgatgttcaagtgagagcagcagtgagctccatgtgcagagaggcagggctctggagtgagtggagccaacctattta tgtgggtaagtagcttatgtttattttacattggcagccttccttgtgatcaaaaaaggtaatcccagaaacgtacccgt tcactcgtgggtcttaaaatggtttcatatctctattgtgactaattttctctcggtctactgccttttcaatcaggaat agatttgccatgaagccagtgaagtttttaagtgtctaggcttctcattagtgccaactctcctagacctggtgcctgtt ttttttccaagttttgtttctacttctatccattttttaaattaaactttttattttgaaataattatcacactcacaag ctgtgggaagaaataatagagatcctgtgtctctttcatccagttttcctcaagggtaacatcttacaaaactatagtac aatagtggaatagaatatttggtgttccgctgcttctcatcgcatggccaccgcatttctcaggccaggcacattgagca ttggtcctgtgcctgacgctatgctagatgctggggttgcagccacgagcatagacacgacagacacggtcctcgccatc ttctgttgagtactggtcggaacaagaggatcgtctgtagacaggctacagattgttttagattgaagtttcctgtcatg ttcactcatctttaaatcctcatagtaaaaaggatatgatcatcgtggcgcatgtattactcatccttttgggggccact gagatactgcaagctgacttacttcctgatgaaaagatttcacttctcccacctgtcaatttcaccattaaagttactgg tttggctcaagttcttttacaatggaaaccaaatcctgatca^'agagcaaaggaatgttaatctagaatatcaagtgaaaa taaacgctccaaaagaagatgactatgaaaccagaatcactgaaagcaaatgtgtaaccatcctccacaaaggcttttca gcaagtgtgcggaccatcctgcagaacgaccactcactactggccagcagctgggcttctgctgaacttcatgccccacc agggtctcctggaacctcaattgtgaatttaacttgcaccacaaacactacagaagacaattattcacgtttaaggtcat accaagtttcccttcactgcacctggcttgttggcacagatgcccctgaggacacgcagtattttctctactataggtat ggctcttggactgaagaatgccaagaatacagcaaagacacactggggagaaatatcgcatgctggtttcccaggacttt ta cctcagcaaagggcgtgactggctttcggtgcttgttaacggctccagcaagcactctgctatcaggccctttgatc agctgtttgcccttcacgccattgatcaaataaatcctccactgaatgtcacagcagagattgaaggaactcgtctctct atccaatgggagaaaccagtgtctgcttttccaatccattgctttgattatgaagtaaaaatacacaatacaaggaatgg atatttgcagatagaaaaattgatgaccaatgcattcatctcaataattgatgatctttctaagtacgatgttcaagtga gagcagcagtgagctccatgtgcagagaggcagggctctggagtgagtggagccaacctatttatgtgggaaatgatgaa cacaagcccttgagagagtggtttgtcattgtgattatggcaaccatctgcttcatcttgttaattctctcgcttatctg taaaatatgtcatttatggatcaagttgtttccaccaattccagcaccaaaaagtaatatcaaagatctctttgtaacca ctaactatgagaaagctgggtccagtgagacggaaattgaagtcatctgttatatagagaagcctggagttgagaccctg gaggattctgtgttttgactgtcactttggcatcctctgatgaactcacacatgcctcagtgcctcagtgaaaagaacag ggatgctggctcttggctaagaggtgttcagaatttaggcaacactcaatttacctgcgaagcaatacacccagacacac cagtcttgtatctcttaaaagtatggatgcttcatccaaatcgcctcacctacagcagggaagttgactcatccaagcat tttgccatgttttttctccccatgccgtacagggtagcacctcctcacctgccaatctttgcaatttgcttgactcacct cagactttcattcacaacagacagcttttaaggctaacgtccagctgtatttacttctggctgtgccgtttggctgttta agctgccaattgtagcactcagctaccatctgaggaagaaagcattttgcatcagcctggagtgaaccatgaacttggat tcaagactgtcttttctatagcaagtcttttgaaaggatctgccgctgcttctcatcgcatggccaccgcatttctcagg ccaggcacattgagcattggtcctgtgcctgacgctatgctagatgctggggttgcagccacgagcatagacacgacaga cacggtcctcgccatcttctgttgagtactggtcggaacaagaggatcgtctgtagacaggatatgatcatcgtggcgca tgtattactcatccttttgggggccactgagatactgcaagctgacttacttcctgatgaaaagatttcacttctcccac ctgtcaatttcaccattaaagttactggtttggctcaagttcttttacaatggaaaccaaatcctgatcaagagcaaagg aatgttaatctagaatatcaagtgaaaataaacgctccaaaagaagatgactatgaaaccagaatcactgaaagcaaatg tgtaaccatcctccacaaaggcttttcagcaagtgtgcggaccatcctgcagaacgaccactcactactggccagcagct gggcttctgctgaacttcatgccccaccagggtctcctggaacctcaattgtgaatttaacttgcaccacaaacactaca gaagacaattattcacgtttaaggtcataccaagtttcccttcactgcacctggcttgttggcacagatgcccctgagga cacgcagtattttctctactataggtatggctcttggactgaagaatgccaagaatacagcaaagacacactggggagaa atatcgcatgctggtttcccaggacttttatcctcagcaaagggcgtgactggcttgcggtgcttgttaacggctccagc aagcactctgctatcaggccctttgatcagctgtttgcccttcacgccattgatcaaataaatcctccactgaatgtcac agcagagattgaaggaactcgtctctctatccaatgggagaaaccagtgtctgcttttccaatccattgctttgattatg aagtaaaaatacacaatacaaggaatggatatttgcagatagaaaaattgatgaccaatgcattcatctcaataattgat gatctttctaagtacgatgttcaagtgagagcagcagtgagctccatgtgcagagaggcagggctctggagtgagtggag ccaacctatttatgtgggtaagtagcttatgtttattttacattggcagccttccttgtgatcaaaaaaggtaatcccag aaacgtacccgttcactcgtgggtcttaaaatggtttcatatctctattgtgactaattttctctcggtctactgccttt tcaatcaggaatagatttgccatgaagccagtgaagtttttaagtgtctaggcttctcattagcgccaccggtcctcgcc a cttctgttgagtactggtcggaacaagaggatcgtctgtagacaggatatgatcatcgtggcgcatgtattactcatc cttttgggggccactgagatactgcaagctgacttacttcctgatgaaaagatttcacttctcccacctgtcaatttcac cattaaagttactggtttggctcaagttcttttacaatggaaaccaaatcctgatcaagagcaaaggaatgttaatctag aatatcaagtgaaaataaacgctccaaaagaagatgactatgaaaccagaatcactgaaagcaaatgtgtaaccatcctc cacaaaggcttttcagcaagtgtgcggaccatcctgcagaacgaccactcactactggccagcagctgggcttctgctga acttcatgccccaccagggtctcctggaacctcagttgtgaatttaacttgcaccacaaacactacagaagacaattatt cacgtttaaggtcataccaagtttcccttcactgcacctggcttgttggcacagatgcccctgaggacacgcagtatttt ctctactataggtatggctcttggactgaagaatgccaagaatacagcaaagacacactggggagaaatatcgcatgctg gtttcccaggacttttatcctcagcaaagggcgtgactggcttgcggtgcttgttaacggctccagcaagcactctgcta tcaggccctttgatcagctgtttgcccttcacgccattgatcaaataaatcctccactgaatgtcacagcagagattgaa ggaactcgtctctctatccaatgggagaaaccagtgtctgcttttccaatccattgctttgattatgaagtaaaaataca caatacaaggaatggatatttgcagatagaaaaattgatgaccaatgcattcatctcaataattgatgatctttctaagt acgatgttcaagtgagagcagcagtgagctccatgtgcagagaggcagggctctggagtgagtggagccaacctatttat gtgggaaatgatgaacacaagcccttgagagagtggtttgtcattgtgattatggcaaccatctgcttcatcttgttaat tctctcgcttatctgtaaaatatgtcatttatggatcaagttgtttccaccaattccagcaccaaaaagtaatatcaaag atctctttgtaaccactaactatgagaaagctgggtccagtgagacggaaattgaagtcatctgttatatagagaagcct ggagttgagaccctggaggattctgtgttttgactgtcactttggcatcctctgatgaactcacacatgcctcagtgcct cagtgaaaagaacagggatgctggctcttggctaagaggtgttcagaatttaggcaacactcaatttacctgcgaagcaa tacacccagacacaccagtcttgtatctcttaaaagtatggatgcttcatccaaatcgcctcacctacagcagggaagtt gactcatccaagcattttgccatgttttttctccccatgccgtacagggtagcacctcctcacctgccaatctttgcaat ttgcttgactcacctcagacttttcattcacaacagacagcttttaaggctaacgtccagctgtatttacttctggctgt gcccgtttggctgtttaagctgccaattgtagcactcagctaccatctgaggaagaaagcattttgcatcagcctggagt gaatcatgaacttggattcaagactgtcttttctatagcaagtgagagccacaaattcctcacccccctacattctagaa tgatctttttctaggtagattgtgtatgtgtgtgtatgagagagagagagagagagagagagagagagagagaaattatc tcaagctccagaggcctgatccaggatacatcatttgaaaccaactaatttaaaagcataatagagctaatatat (SEQ ID NO: 11924) gaattcagtaacccaggcattattttatcctcaagtcttaggttggttggagaaagataacaaaaagaaacatgattgtg cagaaacagacaaacctttttggaaagcatttgaaaatggcattccccctccacagtgtgttcacagtgtgggcaaattc actgctctgtcgtactttctgaaaatgaagaactgttacaccaaggtgaattatttataaattatgtacttgcccagaag cgaacagacttttactatcataagaacccttccttggtgtgctctttatctacagaatccaagacctttcaagaaaggtc ttggattcttttcttcaggacactaggacataaagccacctttttatgatttgttgaaatttctcactccatcccttttg ctgatgatcatgggtcctcagaggtcagacttggtgtccttggataaagagcatgaagcaacagtggctgaaccagagtt ggaacccagatgctctttccactaagcatacaactttccattagataacacctccctcccaccccaaccaagcagctcca gtgcaccactttctggagcataaacataccttaactttacaacttgagtggccttgaatactgttcctatctggaatgtg ctgttctctttcatcttcctctattgaagccctcctattcctcaatgccttgctccaactgcctttggaagattctgctc ttatgcctccactggaattaatgtcttagtaccacttgtctattctgctatatagtcagtccttacattgctttcttctt ctgatagaccaaactctttaaggacaagtacctagtcttatctatttctagatcccccacattactcagaaagttactcc ataaatgtttgtggaactgatttctatgtgaagacatgtgccccttcactctgttaactagcattagaaaaacaaatctt ttgaaaagttgtagtatgcccctaagagcagtaacagttcctagaaactctctaaaatgcttagaaaaagatttatttta aattacctccccaataaaatgattggctggcttatcttcaccatcatgatagcatctgtaattaactgaaaaaaaataat tatgccattaaaagaaaatcatccatgatcttgttctaacacctgccactctagtactatatctgtcacatggtctatga taaagttatctagaaataaaaaagcatacaattgataattcaccaaattgtggagcttcagtattttaaatgtatattaa aattaaattattttaaagatcaaagaaaactttcgtcatactccgtatttgataaggaacaaataggaagtgtgatgact caggtttgccctgaggggatgggccatcagttgcaaatcgtggaatttcctctgacataatgaaaagatgagggtgcata agttctctagtagggtgatgatataaaaagccaccggagcactccataaggcacaaactttcagagacagcagagcacac aagcttctaggacaagagccaggaagaaaccaccggaaggaaccattctcactgtgtgtaaacatgacttccaagctggc cgtggctctcttggcagccttcctgatttctgcagctctgtgtgaaggtaagcacatctttctgacctacagcgttttcc tatgtctaaatgtgatccttagatagcaaagctattcttgatgctttggtaacaaacatcctttttattcagaaacagaa tataatcttagcagtcaattaatgttaaattgaagatttagaaaaaactatatataacacttaggaaatataaaggtttg atcaatatagatattctgcttttataatttataccaggtagcatgcatatatttaacgtaaataagtaatttatagtatg tcctattgagaaccacggttacctatattatgtattaatattgagttgagcaaggtaactcagacaattccactccttgt agtatttcattgacaagcctcagatttgtcattaattcctgtctggtttaaagataccctgattatagaccaggcatgta taacttatttatatatttctgttaattctttctgaaggcaatttctatgctggagagtcttagcttgcctactataaata acactgtggtatcacagaggattatgcaatattgaccagataaaaataccatgaagatgttgatattgtacaaaaagaac tctaactcttatataggaagttgttcaatgttgtcagttatgactgttttttaaaacaaagaactaactgaggtcaaggg ctaggagatattcaggaatgagttcactagaaacatgatgccttccatagtctccaaataatcatattggaattagaagg aagtagctggcagagctgtgcctgttgataaaatcaatccttaatcactttttcccccaacaggtgcagttttgccaagg agtgctaaagaacttagatgtcagtgcataaagacatactccaaacctttccaccccaaatttatcaaagaactgagagt gattgagagtggaccacactgcgccaacacagaaattatgtaagtactttaaaaaagattagatattttgttttagcaaa cttaaaattaaggaaggtggaaatatttaggaaagttccaggtgttaggattacagtagtaaatgaaacaaaacaaaata aaaatatttgtctacatgacatttaaatatggtagcttccacaactactataaatgttattttggacttagactttatgc ctgacttaaggaatcatgatttgaatgcaaaaactaaatattaatctgaaccatttctttcttatttcagtgtaaagctt tctgatggaagagagctctgtctggaccccaaggaaaactgggtgcagagggttgtggagaagtttttgaagaggtaagt tatatattttttaatttaaatttttcatttatcctgagacatataatccaaagtcagcctataaatttctttctgttgct aaaaatcgtcattaggtatctgcctttttggttaaaaaaaaaggaatagcatcaatagtgagtttgttgtacttatgacc agaaagaccatacatagtttgcccaggaaattctgggtttaagcttgtgtcctatactcttagtaaagttctttgtcact cccagtagtgtcctattttagatgataatttctttgatctccctatttatagttgagaatatagagcatttctaacacat gaatgtcaaagactatattgacttttcaagaaccctactttccttcttattaaacatagctcatctttatatttttaatt ttattttagggctgagaattcataaaaaaattcattctctgtggtatccaagaatcagtgaagatgccagtgaaacttca agcaaatctacttcaacacttcatgtattgtgtgggtctgttgtagggttgccagatgcaatacaagattcctggttaaa tttgaatttcagtaaacaatgaatagtttttcattgtaccatgaaatatccagaacatacttatatgtaaagtattattt atttgaatctacaaaaaacaacaaataatttttaaatataaggattttcctagatattgcacgggagaatatacaaatag caaaattgggccaagggccaagagaatatccgaactttaatttcaggaattgaatgggtttgctagaatgtgatatttga agcatcacataaaaatgatgggacaataaattttgccataaagtcaaatttagctggaaatcctggatttttttctgtta aatctggcaaccctagtctgctagccaggatccacaagtccttgttccactgtgccttggtttctcctttatttctaagt ggaaaaagtattagccaccatcttacctcacagtgatgttgtgaggacatgtggaagcactttaagttttttcatcataa cataaattattttcaagtgtaacttattaacctatttattatttatgtatttatttaagcatcaaatatttgtgcaagaa tttggaaaaatagaagatgaatcattgattgaatagttataaagatgttatagtaaatttattttattttagatattaaa tgatgttttattagataaatttcaatcagggtttttagattaaacaaacaaacaattgggtacccagttaaattttcatt tcagatatacaacaaataattttttagtataagtacattattgtttatctgaaattttaattgaactaacaatcctagtt tgatactcccagtcttgtcattgccagctgtgttggtagtgctgtgttgaattacggaataatgagttagaactattaaa acagccaaaactccacagtcaatattagtaatttcttgctggttgaaacttgtttattatgtacaaatagattcttataa tattatttaaatgactgcatttttaaatacaaggctttatatttttaactttagtgtttttatgtgctctccaaattttt tttactgtttctgattgtatggaaatataaaagtaaatatgaaacatttaaaatataatttgttgtcaaagtaatcaagt gtttgtcttttttttagttttagcttattgggattctctttgtttatatttaaaattatactttgatttagaaaacataa atgcttccccttagcattttgttatggaaaattacaaacttttatttttagaaaacagaactcctttccagaaataggtt acaaacagtagtgtcctccacagaatgttggaaatgttttcaactccccactgtatact tcttgctaataagtctgtct tcagatttcgattaaccggtttgtatgtctgtgcactttagcatagctggacattaaagaggaaagagagtacatattat aagttgcttatcagtaactgaggagtaaaactgataaatgtgaggcaaagaagtttaaaatatggttaaagcctaagcat atttgcaaacaaatcaaacaatactctgagaagtaaaaacataattatttaattaacaaatttcagtggataaattttat aacaaattagacacagttgaaaataaaattagaaaactagaaaatagaacaaaagaaacttctggaattca (SEQ ID NO: 11925) tattcat aagtgccctctagctgttaagtcactctgatctctgactgcagctcctactgttggacacacctggccggtg cttcagttagatcaaaccattgctgaaactgaagaggacatgtcaaatattacagatccacagatgtgggattttgatga tctaaatttcactggcatgccacctgcagatgaagattacagcccctgtatgctagaaactgagacactcaacaagtatg ttgtgatcatcgcctatgccctagtgttcctgctgagcctgctgggaaactccctggtgatgctggtca cttatacagc agggtcggccgctccgtcactgatgtctacctgctgaacctggccttggccgacctactctttgccctgaccttgcccat ctgggccgcctccaaggtgaatggctggatttttggcacattcctgtgcaaggtggtctcactcctgaaggaagtcaact tctacagtggcatcctgctgttggcctgcatcagtgtggaccgttacctggccattgtccatgccacacgcacactgacc cagaagcgtcacttggtcaagtttgtttgtcttggctgctggggactgtctatgaatctgtccctgcccttcttcctttt ccgccaggcttaccatccaaacaattccagtccagtttgctatgaggtcctgggaaatgacacagcaaaatggcggatgg tgttgcggatcctgcctcacacctttggcttcatcgtgccgctgtttgtcatgctgttctgctatggattcaccctgcgt acactgtttaaggcccacatggggcagaagcaccgagccatgagggtcatctttgctgtcgtcctcatcttcctgctttg ctggctgccctacaacctggtcctgctggcagacaccctcatgaggacccaggtgatccaggagagctgtgagcgccgca acaacatcggccgggccctggatgccactgagattctgggatttctccatagctgcctcaaccccatcatctacgccttc atcggccaaaattttcgccatggattcctcaagatcctggctatgcatggcctggtcagcaaggagttcttggcacgtca tcgtgttacctcctacacttcttcgtctgtcaatgtctcttccaacctctgaaaaccatcgatgaaggaatatctcttct cagaaggaaagaataaccaacaccctgaggttgtgtgtggaaggtgatctggctctggacaggcac atctgggttttgg ggggacgctataggatgtggggaagttaggaactggtgtcttcaggggccacaccaaccttctgaggagctgttgaggta cctccaaggaccggcctttgcacctccatggaaacgaagcaccatcattcccgttgaacgtcacatctttaacccactaa ctggctaattagcatggccacatctgagccccgaatctgacattagatgagagaacagggctgaagctgtgtcctcatga gggctggatgctctcgttgaccctcacaggagcatctcctcaactctgagtgttaagcgttgagccaccaagctggtggc tctgtgtgctctgatccgagctcaggggggtggttttcccatctcaggtgtgttgcagtgtctgctggagacattgaggc aggcactgccaaaacatcaacctgccagctggccttgtgaggagctggaaacacatgttccccttgggggtggtggatga acaaagagaaagagggtttggaagccagatctatgccacaagaaccccctttacccccatgaccaacatcgcagacacat gtgctggccacctgctgagccccaagtggaacgagacaagcagcccttagcccttcccctctgcagcttccaggctggcg tgcagcatcagcatccctagaaagccatgtgcagccaccagtccattgggcaggcagatgttcctaataaagcttctgtt ccgtgct (SEQ ID NO: 11926) cctacaggtgaaaagcccagcgacccagtcaggatttaagtttacctcaaaaatggaagattttaacatggagagtgaca gctttgaagatttctggaaaggtgaagatcttagtaattacagttacagctctaccctgcccccttttctactagatgcc gccccatgtgaaccagaatccctggaaatcaacaagtattttgtggtcattatctatgccctggtattcctgctgagcct gctgggaaactccctcgtgatgctggtcatcttatacagcagggtcggccgctccgtcactgatgtctacctgctgaacc tagccttggccgacctactctttgccctgaccttgcccatctgggccgcctccaaggtgaatggctggatttttggcaca ttcctgtgcaaggtggtctcactcctgaaggaagtcaacttctatagtggcatcctgctactggcctgcatcagtgtgga ccgttacctggccattgtccatgccacacgcacactgacccagaagcgctacttggtcaaattcatatgtctcagcatct ggggtctgtccttgctcctggccctgcctgtcttacttttccgaaggaccgtctactca ccaatgttagcccagcctgc tatgaggacatgggcaacaatacagcaaactggcggatgctgttacggatcctgccccagtcctttggcttcatcgtgcc actgctgatcatgctgttctgctacggattcaccctgcgtacgctgtttaaggcccacatggggcagaagcaccgggcca tgcgggtcatctttgctgtcgtcctcatcttcctgctttgctggctgccctacaacctggtcctgctggcagacaccctc atgaggacccaggtgatccaggagacctgtgagcgccgcaatcacatcgaccgggctctggatgccaccgagattctggg catccttcacagctgcctcaaccccctcatctacgccttcattggccagaagtttcgccatggactcctcaagattctag ctatacatggcttgatcagcaaggactccctgcccaaagacagcaggccttcctttgttggctcttcttcagggcacact tccactactctctaagacctcctgcctaagtgcagccccgtggggttcctcccttctcttcacagtcacattccaagcct catgtccactggttcttcttggtctcagtgtcaatgcagcccccattgtggtcacaggaagcagaggaggccacgttctt actagtttcccttgcatggtttagaaagcttgccctggtgcctcaccccttgccataattactatgtcatttgctggagc tctgcccatcctgcccctgagcccatggcactctatgttctaagaagtgaaaatctacactccagtgagacagctctgca tactcattaggatggctagtatcaaaagaaagaaaatcaggctggccaacgggatgaaaccctgtctctactaaaaatac aaaaaaaaaaaaaaaaattagccgggcgtggtggtgagtgcctgtaatcacagctacttgggaggctgagatgggagaat cacttgaacccgggaggcagaggttgcagtgagccgagattgtgcccctgcactccagcctgagcgacagtgagactctg tctcagtccatgaagatgtagaggagaaactggaactctcgagcgttgctgggggggattgtaaaatggt (SEQ ID NO: 11927) ggatccaagtaggattgagtgtcctgtagttattatccacagggaacattctacaaagttttgggagactgtaatgtcat gggaaatgcaagaatatgtgtccagcatggaagggaatcagtatggaagtcttttgataaattgtggcatt atcactaa cattgcctcaaaactttagactacctgccatatacaaattagaggtgaaaattacttccatgtaatatacaagccaacac aaagaatcctatcccagtttcttggatggataggcaagaatctgggtaaggtttattgtgcaataatcctcttctctctt ctataggccaggatttaagtttacctcaaaaatggaaaattttggctgggaaaattacatgtgggaagacatcttcagtg gagattttagtaattacagtttcagctatgaccctaccccttttctactagattctgccccatgttggccagaatcccta gaaatcaattatgttttgatcatcatctatgccctgatgtttctactgaacgtgatgtgaaactccctgccgatgctggt catcttattcagctgagtcagccactgtcaccgatgtctacctgctgaccctggccttggccgacctgttcttttccctg acattgcccatcttggctgcctccaagatgaatggctggatttttggcacaatctgtgccaggtggtctagctcctgaag gaagtcaacttctacggtggtattctactactggcctgccgcagcatggactgttacctggccattgtccatgccacacg cacactgacccagcagcgccacttggtcaagttcatatgtctgggtttgtggaacctgttcctgttactgtccctacgca tcttgcttttccgaaggaccttctacccatccaatgttagcccagtctgctatgaggacatgggcaacaatacagcaaac tggtggatgctgttacggatcctgccccagtcctttggcttcatcgtgccgctgcgatcatgctgttctgctacagattc accctgcatacgctgtttaaggcccatatggggcagaagcactggaccatgtgggtcatctttgctgttgtcctcatttt cctgctctgctggctgccctacaacctggtcctgctggcagacaccctcatgggaacccagatgaccaatgagacctgtg agcgccgcaacgacatcaaccaggccctggatgccactgagattctgggcatccttcacagctacctcaatcccctcatc tacgccttcattggccagaagttttgccatggacttctcaagattatagccatacacggcttgatcagcaaggactccct gcccaaagacagcaggccttcctttgttggctcttcttcagggcacacttccactactctctaagacctcttgcctaagt gcagtcccgtggggttcctcccttctcttcacagtcacattccaagcctcatgtccactagctcttcttggtctcagtgt cagtgcagcccccactgtggtcgcaggaagcagaggaggccacgttcttactagtttcccttgcatgatttagaaagcct gccctggtacctcaccccttgccataattactacatcacttgctggagctctgtccctcctgcccttgagctcatggcac tctatgttctaagaagtgaaaatctacactccagtgagacagctctgcatactca taggatggttaatgtcagaagaaa gaaaatcataaaatagaaggtgtccacaaaggtgcagatgataagtg (SEQ ID NO: 11928) gtcaggatttaagtttacctcaaaaatggaagattttaacatggagagtgacagctttgaagatttctggaaaggtgaag atcttagtaattacagttacagctctaccctgcccccttttctactagatgccgccccatgtgaaccagaatccctggaa atcaacaagtattttgtggtcattatctatgccctggtattcctgctgagcctgctgggaaactccctcgtgatgctggt catcttatacagcagggtcggccgctccgtcactgatgtctacctgctgaacctagccttggccgacctactctttgccc tgaccttgcccatctgggccgcctccaaggtgaatggctggatttttggcacattcctgtgcaaggtggtctcactcctg aaggaagtcaacttctatagtggcatcctgctactggcctgcatcagtgtggaccgttacctggccattgtccatgccac acgcacactgacccagaagcgctacttggtcaaattcatatgtctcagcatctggggtctgtccttgctcctggccctgc ctgtcttacttttccgaaggaccgtctactcatccaatgttagcccagcctgctatgaggacatgggcaacaatacagca aactggcggatgctgttacggatcctgccccagtcctttggcttcatcgtgccactgctgatcatgctgttctgctacgg attcaccctgcgtacgctgtttaaggcccacatggggcagaagcaccgggccatgcgggtcatctttgctgtcgtcctca tcttcctgctttgctggctgccctacaacctggtcctgctggcagacaccctcatgaggacccaggtgatccaggagacc tgtgagcgccgcaatcacatcgaccgggctctggatgccaccgagattctgggcatccttcacagctgcctcaaccccct catctacgccttcattggccagaagtttcgccatggactcctcaagattctagctatacatggcttgatcagcaaggact ccctgcccaaagacagcaggccttcctttgttggctcttcttcagggcacacttccactactctctaagacctcctgcct aagtgcagcccgtggggttcctcccttctcttcaσagtcacattccaagcctcatgtccactggttcttcttggtctcag tgtcaatgcagcccccattgtggtcacaggaagcagaggaggccacgttcttactagtttcccttgcatggtttagaaag cttgccctggtgcctcaccccttgccataattactatgtcatttgctggagctctgcccatcctgcccctgagcccatgg cactctatgttctaagaagtgaaaatctacactccagtgagacagctctgcatactcattaggatggctagtatcaaaag aaagaaaatcaggctggccaacgggatgaaaccctgtctctactaaaaatacaaaaaaaaaaaaaaaaaa (SEQ ID NO: 11929) gggagaaacatagggaatagaaaataagtaagaaggggacacctgggaacaggtttgccttcttgcattttgcttaatgc tggcccttccctgaatgtctaagaccaacctggtccccacatccaaatgcacagacacagctgaggatggagaaggctaa agagggacagaggtagagacataggctgagaggaggcagttgtaggttgagctagggctaaggtgttttccccatattcc atcttaccccacactcaggccaggccttagagttgtggaaggtggagaacactgggaagccaacctccgaagaagaccag gttggagtcaaaggaggaaggagagctctcattgccaaaccaacagggaagccaaggatatcccagtaactgctctcaca tcattgatgagaatgccttgaatccgagctactaaatcacatttccttccttctaaccttccagttagatcaaaccattg ctgaaactgaagaggacatgtcaaatattacagatccacagatgtgggattttgatgatctaaatttcactggcatgcca cctgcagatgaagattacagcccctgtatgctagaaactgagacactcaacaagtatgttgtgatcatcgcctatgccct agtgttcctgctgagcctgctgggaaactccctggtgatgctggtcatcttatacagcagggtcggccgctccgtcactg atgtctacctgctgaacctggccttggccgacctactctttgccctgaccttgcccatctgggccgcctccaaggtgaat ggctggatttttggcacattcctgtgcaaggtggtctcactcctgaaggaagtcaacttctacagtggcatcctgctgtt ggcctgcatcagtgtggaccgttacctggccattgtccatgccacacgcacactgacccagaagcgtcacttggtcaagt ttgtttgtcttggctgctggggactgtctatgaatctgtccctgcccttcttccttttccgccaggcttaccatccaaac aattccagtccagtttgctatgaggtcctgggaaatgacacagcaaaatggcggatggtgttgcggatcctgcctcacac ctttggcttcatcgtgccgctgtttgtcatgctgttctgctatggattcaccctgcgtacactgtttaaggcccacatgg ggcagaagcaccgagccatgagggtcatctttgctgtcgtcctcatcttcctgctttgctggctgccctacaacctggtc ctgctggcagacaccctcatgaggacccaggtgatccaggagagctgtgagcgccgcaacaacatcggccgggccctgga tgccactgagattctgggatttctccatagctgcctcaaccccatcatctacgccttcatcggccaaaattttcgccatg gattcctcaagatcctggctatgcatggcctggtcagcaaggagttcttggcacgtcatcgtgttacctcctacacttct tcgtctgtcaatgtctcttccaacctctgaaaaccatcgatgaaggaatatctcttctcagaaggaaagaataaccaaca ccctgaggttgtgtgtggaaggtgatctggctctggacaggcactatctgggttttggggggacgctataggatgtgggg aagttaggaactggtgtcttcaggggccacaccaaccttctgaggagctgttgaggtacctccaaggaccggcctttgca cctccatggaaacgaagcaccatcattcccgttgaacgtcacatctttaacccactaactggctaattagcatggccaca tctgagccccgaatctgacattagatgagagaacagggctgaagctgtgtcctcatgagggctggatgctctcgttgacc ctcacaggagcatctcctcaactctgagtgttaagcgttgagccaccaagctggtggctctgtgtgctctgatccgagct caggggggtggttttcccatctcaggtgtgttgcagtgtctgctggagacattgaggcaggcactgccaaaacatcaacc tgccagctggccttgtgaggagctggaaacacatgttccccttgggggtggtggatgaacaaagagaaagagggtttgga agccagatctatgccacaagaaccccctttacccσcatgaccaacatcgcagacacatgtgctggccacctgctgagccc caagt (SEQ ID NO: 11930) tattcatcaagtgccctctagctgttaagtcactctgatctctgactgcagctcctactgttggacacacctggccggtg cttcagttagatcaaaccattgctgaaactgaagaggacatgtcaaatattacagatccacagatgtgggattttgatga tctaaatttcactggcatgccacctgcagatgaagattacagcccctgtatgctagaaactgagacactcaacaagtatg ttgtgatcatcgcctatgccctagtgttcctgctgagcctgctgggaaactccctggtgatgctggtcatctt tacagc agggtcggccgctccgtcactgatgtctacctgctgaacctggccttggccgacctactctttgccctgaccttgcccat ctgggccgcctccaaggtgaatggctggatttttggcacattcctgtgcaaggtggtctcactcctgaaggaagtcaact tctacagtggcatcctgctgttggcctgcatcagtgtggaccgttacctggccattgtccatgccacacgcacactgacc cagaagcgtcacttggtcaagtttgtttgtcttggctgctggggactgtctatgaatctgtccctgcccttcttcctttt ccgccaggcttaccatccaaacaattccagtccagtttgctatgaggtcctgggaaatgacacagcaaaatggcggatgg tgttgcggatcctgcctcacacctttggcttcatcgtgccgctgtttgtcatgctgttctgctatggattcaccctgcgt acactgtttaaggcccacatggggcagaagcaccgagccatgagggtcatctttgctgtcgtcctcatcttcctgctttg ctggctgccctacaacctggtcctgctggcagacaccctcatgaggacccaggtgatccaggagagctgtgagcgccgca acaacatcggccgggccctggatgccactgagattctgggatttctccatagctgcctcaacccca catctacgccttc atcggccaaaattttcgccatggattcctcaagatcctggctatgcatggcctggtcagcaaggagttcttggcacgtca tcgtgttacctcctacacttcttcgtctgtcaatgtctcttccaacctctgaaaaccatcgatgaaggaatatctcttct cagaaggaaagaataaccaacaccctgaggttgtgtgtggaaggtgatctggctctggacaggcactatctgggttttgg ggggacgctataggatgtggggaagttaggaactggtgtcttcaggggccacaccaaccttctgaggagctgttgaggta cctccaaggaccggcctttgcacctccatggaaacgaagcaccatcattcccgttgaacgtcacatctttaacccactaa ctggctaattagcatggccacatctgagccccgaatctgacattagatgagagaacagggctgaagctgtgtcctcatga gggctggatgctctcgttgaccctcacaggagcatctcctcaactctgagtgttaagcgttgagccaccaagctggtggc tctgtgtgctctgatccgagctcaggggggtggttttcccatctcaggtgtgttgcagtgtctgctggagacattgaggc aggcactgccaaaacatcaacctgccagctggccttgtgaggagctggaaacacatgttccccttgggggtggtggatga acaaagagaaagagggtttggaagccagatctatgccacaagaaccccctttacccccatgaccaacatcgcagacacat gtgctggccacctgctgagccccaagtggaacgagacaagcagcccttagcccttcccctctgcagcttccaggctggcg tgcagcatcagcatccctagaaagccatgtgcagccaccagtccattgggcaggcagatgttcctaataaagcttctgtt ccgtgctcctacaggtgaaaagcccagcgacccagtcaggatttaagtttacctcaaaaatggaagattttaacatggag agtgacagctttgaagatttctggaaaggtgaagatcttagtaattacagttacagctctaccctgcccccttttctact agatgccgccccatgtgaaccagaatccctggaaatcaacaagtattttgtggtcattatctatgccctggtattcctgc tgagcctgctgggaaactccctcgtgatgctggtcatcttatacagcagggtcggccgctccgtcactgatgtctacctg ctgaacctagccttggccgacctactctttgccctgaccttgcccatctgggccgcctccaaggtgaatggctggatttt tggcacattcctgtgcaaggtggtctcactcctgaaggaagtcaacttctatagtggcatcctgctactggcctgcatca gtgtggaccgttacctggccattgtccatgccacacgcacactgacccagaagcgctacttggtcaaattcatatgtctc agcatctggggtctgtccttgctcctggccctgcctgtcttacttttccgaaggaccgtctactcatccaatgttagccc agcctgctatgaggacatgggcaacaatacagcaaactggcggatgctgttacggatcctgccccagtcctttggcttca tcgtgccactgctgatcatgctgttctgctacggattcaccctgcgtacgctgtttaaggcccacatggggcagaagcac cgggccatgcgggtcatctttgctgtcgtcctcatcttcctgctttgctggctgccctacaacctggtcctgctggcaga caccctcatgaggacccaggtgatccaggagacctgtgagcgccgcaatcacatcgaccgggctctggatgccaccgaga ttctgggcatccttcacagctgcctcaaccccctcatctacgccttcattggccagaagtttcgccatggactcctcaag attctagctatacatggcttgatcagcaaggactccctgcccaaagacagcaggccttcctttgttggctcttcttcagg gcacacttccactactctctaagacctcctgcctaagtgcagccccgtggggttcctcccttctcttcacagtcacattc caagcctcatgtccactggttcttcttggtctcagtgtcaatgcagcccccattgtggtcacaggaagcagaggaggcca cgttcttactagtttcccttgcatggtttagaaagcttgccctggtgcctcaccccttgccataattactatgtcatttg ctggagctctgcccatcctgcccctgagcccatggcactctatgttctaagaagtgaaaatctacactccagtgagacag ctctgcatactcattaggatggctagtatcaaaagaaagaaaatcaggctggccaacgggatgaaaccctgtctctacta aaaatacaaaaaaaaaaaaaaaaattagccgggcgtggtggtgagtgcctgtaatcacagctacttgggaggctgagatg ggagaatcacttgaacccgggaggcagaggttgcagtgagccgagattgtgcccctgcactccagcctgagcgacagtga gactctgtctcagtccatgaagatgtagaggagaaactggaactctcgagcgttgctgggggggattgtaaaatggtgga tccaagtaggattgagtgtcctgtagttattatccacagggaacattctacaaagttttgggagactgtaatgtcatggg aaatgcaagaatatgtgtccagcatggaagggaatcagtatggaagtcttttgataaattgtggcatttatcactaacat tgcctcaaaactttagactacctgccatatacaaattagaggtgaaaattacttccatgtaatatacaagccaacacaaa gaatcctatcccagtttcttggatggataggcaagaatctgggtaaggtttattgtgcaataatcctcttctctcttcta taggccaggatttaagtttacctcaaaaatggaaaattttggctgggaaaattacatgtgggaagacatcttcagtggag attttagtaattacagtttcagctatgaccctaccccttttctactagattctgccccatgttggccagaatccctagaa atcaattatgttttgatcatcatctatgccctgatgtttctactgaacgtgatgtgaaactccctgccgatgctggtcat cttattcagctgagtcagccactgtcaccgatgtctacctgctgaccctggccttggccgacctgttcttttccctgaca ttgcccatcttggctgcctccaagatgaatggctggatttttggcacaatctgtgccaggtggtctagctcctgaaggaa gtcaacttctacggtggtattctactactggcctgccgcagcatggactgttacctggccattgtccatgccacacgcac actgacccagcagcgccacttggtcaagttcatatgtctgggtttgtggaacctgttcctgttactgtccctacgcatct tgcttttccgaaggaccttctacccatccaatgttagcccagtctgctatgaggacatgggcaacaatacagcaaactgg tggatgctgttacggatcctgccccagtcctttggcttcatcgtgccgctgcgatcatgctgttctgctacagattcacc ctgcatacgctgtttaaggcccatatggggcagaagcactggaccatgtgggtcatctttgctgttgtcctcattttcct gctctgctggctgccctacaacctggtcctgctggcagacaccctcatgggaacccagatgaccaatgagacctgtgagc gccgcaacgacatcaaccaggccctggatgccactgagattctgggcatccttcacagctacctcaatcccctcatctac gccttcattggccagaagttttgccatggacttctcaagattatagccatacacggcttgatcagcaaggactccctgcc caaagacagcaggccttcctttgttggctcttcttcagggcacacttccactactctctaagacctcttgcctaagtgca gtcccgtggggttcctcccttctcttcacagtcacattccaagcctcatgtccactagctcttcttggtctcagtgtcag tgcagcccccactgtggtcgcaggaagcagaggaggccacgttct actagtttcccttgcatgatttagaaagcctgcc ctggtacctcaccccttgccataattactacatcacttgctggagctctgtccctcctgcccttgagctcatggcactct atgttctaagaagtgaaaatctacactccagtgagacagctctgcatactcattaggatggttaatgtcagaagaaagaa aatcataaaatagaaggtgtccacaaaggtgcagatgataagtggtcaggatttaagtttacctcaaaaatggaagattt taacatggagagtgacagctttgaagatttctggaaaggtgaagatcttagtaattacagttacagctctaccctgcccc cttttctactagatgccgccccatgtgaaccagaatccctggaaatcaacaagtattttgtggtcattatctatgccctg gtattcctgctgagcctgctgggaaactccctcgtgatgctggtcatcttatacagcagggtcggccgctccgtcactga tgtctacctgctgaacctagccttggccgacctactctttgccctgaccttgcccatctgggccgcctccaaggtgaatg gctggatttttggcacattcctgtgcaaggtggtctcactcctgaaggaagtcaacttctatagtggcatcctgctactg gcctgcatcagtgtggaccgttacctggccattgtccatgccacacgcacactgacccagaagcgctacttggtcaaatt catatgtctcagcatctggggtctgtccttgctcctggccctgcctgtcttacttttccgaaggaccgtctactcatcca atgttagcccagcctgctatgaggacatgggcaacaatacagcaaactggcggatgctgttacggatcctgccccagtcc tttggcttcatcgtgccactgctgatcatgctgttctgctacggattcaccctgcgtacgctgtttaaggcccacatggg gcagaagcaccgggccatgcgggtcatctttgctgtcgtcctcatcttcctgctttgctggctgccctacaacctggtcc tgctggcagacaccctcatgaggacccaggtgatccaggagacctgtgagcgccgcaatcacatcgaccgggctctggat gccaccgagattctgggcatccttcacagctgcctcaaccccctcatctacgccttcattggccagaagtttcgccatgg actcctcaagattctagctatacatggcttgatcagcaaggactccctgcccaaagacagcaggccttcctttgttggct cttcttcagggcacacttccactactctctaagacctcctgcctaagtgcagcccgtggggttcctcccttctcttcaca gtcacattccaagcctcatgtccactggttcttcttggtctcagtgtcaatgcagcccccattgtggtcacaggaagcag aggaggccacgttcttactagtttcccttgcatggtttagaaagcttgccctggtgcctcaccccttgccataattacta tgtcatttgctggagctctgcccatcctgcccctgagcccatggcactctatgttctaagaagtgaaaatctacactcca gtgagacagctctgcatactcattaggatggctagtatcaaaagaaagaaaatcaggctggccaacgggatgaaaccctg tctctactaaaaatacaaaaaaaaaaaaaaaaaagggagaaacatagggaatagaaaataagtaagaaggggacacctgg gaacaggtttgccttcttgcattttgcttaatgctggcccttccctgaatgtctaagaccaacctggtccccacatccaa atgcacagacacagctgaggatggagaaggctaaagagggacagaggtagagacataggctgagaggaggcagttgtagg ttgagctagggctaaggtgttttccccatattccatcttaccccacactcaggccaggccttagagttgtggaaggtgga gaacactgggaagccaacctccgaagaagaccaggttggagtcaaaggaggaaggagagctctcattgccaaaccaacag ggaagccaaggatatcccagtaactgctctcacatcattgatgagaatgccttgaatccgagctactaaatcacatttcc ttccttctaaccttccagttagatcaaaccattgctgaaactgaagaggacatgtcaaatattacagatccacagatgtg ggattttgatgatctaaatttcactggcatgccacctgcagatgaagattacagcccctgtatgctagaaactgagacac tcaacaagtatgttgtgatcatcgcctatgccctagtgttcctgctgagcctgctgggaaactccctggtgatgctggtc atcttatacagcagggtcggccgctccgtcactgatgtctacctgctgaacctggccttggccgacctactctttgccct gaccttgcccatctgggccgcctccaaggtgaatggctggatttttggcacattcctgtgcaaggtggtctcactcctga aggaagtcaacttctacagtggcatcctgctgttggcctgcatcagtgtggaccgttacctggccattgtccatgccaca cgcacactgacccagaagcgtcacttggtcaagtttgtttgtcttggctgctggggactgtctatgaatctgtccctgcc cttcttccttttccgccaggcttaccatccaaacaattccagtccagtttgctatgaggtcctgggaaatgacacagcaa aatggcggatggtgttgcggatcctgcctcacacctttggcttcatcgtgccgctgtttgtcatgctgttctgctatgga ttcaccctgcgtacactgtttaaggcccacatggggcagaagcaccgagccatgagggtcatctttgctgtcgtcctcat cttcctgctttgctggctgccctacaacctggtcctgctggcagacaccctcatgaggacccaggtgatccaggagagct gtgagcgccgcaacaacatcggccgggccctggatgccactgagattctgggatttctccatagctgcctcaaccccatc atctacgccttcatcggccaaaattttcgccatggattcctcaagatcctggctatgcatggcctggtcagcaaggagtt cttggcacgtcatcgtgttacctcctacacttcttcgtctgtcaatgtctcttccaacctctgaaaaccatcgatgaagg aatatctcttctcagaaggaaagaataaccaacaccctgaggttgtgtgtggaaggtgatctggctctggacaggcacta tctgggttttggggggacgctataggatgtggggaagttaggaactggtgtcttcaggggccacaccaaccttctgagga gctgttgaggtacctccaaggaccggcctttgcacctccatggaaacgaagcaccatcattcccgttgaacgtcacatct ttaacccactaactggctaattagcatggccacatctgagccccgaatctgacattagatgagagaacagggctgaagct gtgtcctcatgagggctggatgctctcgttgaccctcacaggagcatctcctcaactctgagtgttaagcgttgagccac caagctggtggctctgtgtgctctgatccgagctcaggggggtggttttcccatctcaggtgtgttgcagtgtctgctgg agacattgaggcaggcactgccaaaacatcaacctgccagctggccttgtgaggagctggaaacacatgttccccttggg ggtggtggatgaacaaagagaaagagggtttggaagccagatctatgccacaagaaccccctttacccccatgaccaaca tcgcagacacatgtgctggccacctgctgagccccaagt (SEQ ID NO: ) ccgctgtcaagatgcttctggccatggtcct tacctctgccctgctcctgtgctccgtggcaggccaggggtgtccaaccttggcggggatcctggacatcaacttcctca tcaacaagatgcaggaagatccagcttccaagtgccactgcagtgctaatgtgaccagttgtctctgtttgggcattccc tctgacaactgcaccagaccatgcttcagtgagagactgtctcagatgaccaataccaccatgcaaacaagatacccact gattttcagtcgggtgaaaaaatcagttgaagtactaaagaacaacaagtgtccatatttttcctgtgaacagccatgca accaaaccacggcaggcaacgcgctgacatttctgaagagtcttctggaaattttccagaaagaaaagatgagagggatg agaggcaagatatgaagatgaaatattatttatcctatttattaaatttaaaaagctttctctttaagttgctacaattt aaaaatcaagtaagctactctaaatcagtatcagttgtgattatttgtttaacattgtatgtctttattttgaaataaat (SEQ ID NO:11932) atatatatatgcataatagtctctgtgtaacagtaagtggatgcagtaactggtgtgagggcaacttggagagtgtgctt ggaggcacagagatgctcagggctgcctggactgcctccatgatggtggcctgctctgtattaggtgagtgttcaggaaa ggtgagggcagggcagcccacagcttcacagtggcccagggaagcagggcaggcaggctatgaggcctagtaggcatctg ggccagactttgacactgaggccatggaatgggtggggctctgagaacagacccaagtgatcatgggctgaaggctatgt ccacagatccaaggcgggataggctgtactgggcagtgatgtcagccaggctccccagcgggactgggggtgtcaggggc agctctgtcccaggtggcagacactggtttcccctcctgctctcacaaccggcctgttaccaggtgttgtctgagctgtg gtgaggcttccctggtgacattcaggagcagggagcctgcgagtaagggtgtatgcatctgccctgactgcctggccctg tggtcaaggatgggggaaggcagctctgcctgcagctccaccccatttataaagcactgtggtgccttctgctgggacat gtgctgagtggtgcctcgcaggcactgccctcgggaagttcacaggcttatgtggaagctggtgggaatgggccaagaag agaggtgtcaggagccaggtattgggcaggtcccaggtctctgagcctcagtttcttcatctgtaggagggtggtgaccc tgccctgctcagcttaccaggtacagatgtaagttttcagtgcagaggaaaagcagagaacttcccctcagatggccata cccccttgtcgctgtacccaactctccggtcctactttgtagctctcaggtgtcacatgtggatcctgccctaccatccc ccttgccctgtctagaaacgaggcctgctgagcttggaaccatcccactccctgctctcaagccgtctgctcctgggtta gcctgtggctgacctggcctgattctacatagatgtgggtgtttctccactgctggggcagcagttgtccattctggggc ctgggtcagctctcagctgtggccgttgtgcctgtgcttccccaggtcctggtggtgactccaaccctgccctcacatat cccaagagcaggctgactgccttccccattcccacctttccagtaactgctgcaagaacggacagacactgctgcagaga acttgccacggtgtttcatgctgtggctggtggttccaggctgcacgctccattctaggaaagggtgaggcttcctgatc atcagtcttaacaggggactgtcctatgggtacctgtatacgctgccgggagtggggcagagtggggttagagtagtgcc tgctgcccattggggttgtgcgggttccttaagggctgtagtctgtgtgcgtgtctggttttttcctcctccttatcagt aatcagtcttgtataaccaggctggccctgcttcctgcctaggggctatcggtgtaccatctggagttgcaaatggggtg atagggcgtcagcggccttcccacacccaagcacttcctgacacccagcccctcatctctagccaacctctggctcccct agggatcctggggctcaggcctcacgctccagcatccgggggctttgcccttctggtgttgctcttctttgcaggtgcct tggaacaggggtgcaacagagttcagaaagtgccatctgttgcatggataccctgctgccaccctcgtccacctttctgg ggcagaacagttggatgggtctttatttaagaggacaaaagggagagagaatgcatagaggctgggtctggtggctcacg cctgtaatcccaacactttgggaggccaaggcaggtggatcccttgaggtcaggaggtcaagactagcctggccaacatg gtgaaaccccgtctctactaaaaatacaaaaaaaaaaaaattagctgggcatggcgggagatgcctgtaatcccagctac tcgggaggctgaggcaggataatcacttgaacccaggaggcggaggttgcagtgagccaagatcacaccactgcactcta gcctgggtgacagagggagactgtctcaaaaaaaaaaatttgcttagaatttgtctgtgtgaccctgggcaagtcatttc ccctccttgggactcagttccttgcctgtgaacggggacagtgcttctcccttacagagctgttgtgagaattaaagtag aaaatgtacctatggtggttgttggtagtgaccagttcccccaaccctgactcccctgcaggatggggcctgggcccggg aatgggggatgggctggcagaggatgactgtcccagagaggagtcttctcggcagatgtggagacctagctgagtcagag gccaggatctaagtttgagggtgttccttacaccctgcagccatgagtctttggctgagtcaaatggcctttctgagctc agttccttatcagtaaagcctggacagtggtccaggacgctggacactgtgtgagtgttaggacacaggacactgtgtga gtgcaggtggggacccatggagcactctgctggggagcaattcatggggagcacccctccagagagggatgatttgcaca gggccctcagcccagtcccttgcaggctggaccttggagagtgaggccctgaggcgagacatgggcacctggctcctggc ctgcatctgc (SEQ ID NO: 11933) ggatccatgcccagaattattcacgaaattcacttaaaatagcatatatgcttgaacccaggagtctgaggctgcagcga gctatgatcatgtcactgcactccagcccagcctgggcgacagagcaagactctgtgtctaaagaaatgaaaataaaaat aaataaaatagcatatacaggcaacaatccaaatgttcattgcagaaattatgattattattgtttttcttttagaggca gggtgtcactctgttgcccagactaatcttgacctcctgtgatcctcaagagatcctccggtctctgcttcccaaagttc ttggattacaggtgtgaggcactgggcctagacattgcagggattattaaaccatggtgcatactaccattaaaggtatg aggtaggttttatatgctgacctagaaagatggtgcaacaccataggggaacaagaaggctgcaaagtggcagcacagca ggagtctttaagaaataggtatttgtttcagcttaagaagtgtctggctgggcgtggtggctcacacctgtaatcccagc acttagggaggcttaggtgggcggatcacttgaggttaggagttcaagaccagcccagtcaacaccggtgaaaccccatc tctactaaaaatacaaagaaattagctgggcttggtggcaggtggctgtaatcccagctactcaggagctgaggcaggag aatcatctgaacccgggaggccgaggttgcagtgagcctagatcgcaccactgcactccagcctgggtgacagagtaaga ctcggtcaaaaaaaaaaaaaaaaaagaccgggtgcgaggtctctcgcctgtaatcccagcactttgggaggcctaggcag gaggatcacaaggtcaggagatcgagaccatcctggccaacatggtgaaaccccatctctactaaaatacaaaaattagc cgggtgtgatggcacacgcctgtagtcccagctactcaggaggctgaggcaggggaatcgcttgaaaccaggaggtggag gctgcagtgagccgagatcacgccactgcactccagcctggcgacagagcaagactccatctcaaaaaagaaaagaaaac aaacaaacaaacaaaatccccaaaaagcaaaagtgtctgcatggacttgtgcctaactactcacagtggctacttcttgg gggaggtgaaaggggaccctgttaaagaatttttcttctgtattgtttttcttcaactgagtctgcattaattttatatt taatactctccccacccctgatgctcacaggttgctttagctggtggaaggagaacctgcacctctggttttggcaaagt gtagaaggggacaagggcactgctctgcacctgcacaggttcttgcctcctggggtcagtttaatgaatctcagtggtgt ttcttgggaagaacacagtggacactcacttgccagtcagtagacaaatcactgaagtccatgtctggcagttctcaatg tcatggggactgtaaggttgtcatgtctcacagttccctgacttagaagattagtggtgacagacacttctcagctctgc tcgggagagcagctctgtaatgcgcttgtggtttcagatgtgggcggcctgtgtgaacctgtcgtgcaaagctcacgtca ccaactgctgcagttatctcctgaatcaggctgagggtctttgctgtgcacccagagatagttgggtgacaaatcacctc caggttggggatgcctcagacttgtgatgggactgggcagatgcatctgggaaggtgagtctgtgctttgggcttcccaa cctctcaagtcagcatgaaattcagaaggcagagagggacatgtggccctccaactcggggcccagggagccactgtggc atttgagagcgccaccctagctttacctcctctggtgtcctggccttgtgtatctcttagagatggcaaaatttgcagcc ctgacctcaaggattacaaactaatttccagtcctgtaggggtcatgggttctgctgtggccagtgtggcactgagtttg tcaggcagaatttctaattatggaaggaactctgcttcctcagtgattgaactgacctttgtgggggtgcctttgtgggg tgagaatgggcatacttgggcctcagttgtgatggccatggggtggagctgaggtctaggcccagggctgggaaagcttc taccaaccccgaggcatttgggtgttttagggcagaagaggagccaggaggatgggtatgccccactggagctgtgtgtg gggcagcaggtgagggtgggattccagagggagggtcaacccagccaagcagaggaaggggaggagagggtttgttttgg aaagaacatcaccctctcagtttcctggggtctggatagcctgttcttgtgatgagctggaggatgtgggccctgcttgg at ctcctctcccctccctgcccccattttctcttcctgtgatttatgctgttctgggctcaccctcttcccagagctct cacgctacagctgacaggcagggcaggcgttttaattattattaatttttttttgagacagagtttgagacagtatcaag agtgggtatcctctcagcgtgtcttcaagtagcatcccagagccccgctcctgggtacccacaacatgaacaccgtccag aagcaagggcagcctctgcaggtggggcgggggttggaaaacatttatcaaacggttgagttgggtgcaggggatgcaac atgatcaaacagggtcttgcctccaggagcctcatgtagggacaacgcacagtgatgaccttcaactgcagtggggcagc aaggctgtgggaggggtgttttgggcagagcaggcgacgtgggtacctcttcaccaagacagcaggaagagcacggacat cattttcccgtctcacctccagactcccaggggactgtgccaatatcctcactggagccctgcccatggccactgctcaa cccttgggccctgtcagttcagggctgtgcagaaggagagttgcctgtgctcaggctcaggggttccgtccagctaagga ggcctactaggggactggggaaaggcctcatgaaggaccaggcctgtgatggggagggaagatggcagaggggacagtgg gaagcagagcagcaggggtctcctccacgcctctctgtacttctcccacccacccttgcctgctcccctctgccctgggt atgtgcccttgtccacccaacacctctgcagtgccaagtccagccctgacttcttcctgagctgtggcccagcgttccca caggcatttacctcacggatgcagcactgcccctcatcctcttctctgaaagtgtgtgggaaatgcttcttggtgccatc tctctcccaccctgccttccctgcaccttctctatgaggtgtctgttgtctctgtacttgcctccagctggcctttcaga ccccatccctccctgcctcctgcccatccctacccctgtcagcaccttacatactctgtgcccaacagcattggggattc ccactgtgctgaaggaagtcctcatgtggtccagagagggagctggcccctgctcccatttccagcaccattttctggca caggctccatgtccccaggctccagctgcttctggggtaccaaggtctgcatttcttcctcttcccccagcagacagaag accttgctggacaggtgtccacttcaatagtaacttctgaggctgccagcctcctgaatggtccagaagaaccagaccct tccccgcccccattaaaaaagacaaaatatggccaggcatgttggctcatgcctgacatcccagcactttgggaggccaa agcaggtgaatcacttgaggccaggagtacgagaccagcctgacaaacatggtgaaaccctgtgtctactaaaaatacaa aaattagccaggcgtggtgactcatgcttgtaaatgcttgtaatcccagctacttgggaggctgaagcaggaggatcact tgaactcgggaggcagaggttgcagtgagccgagatcacgccactgtgttccagcctgagcgacagagcgacactccgtc taaaaaaaaaaaatatatatatatatacacacatatatatatgcataatagtctctgtgtaacagtaagtggatgcagta actggtgtgagggcaacttggagagtgtgcttggaggcacagagatgctcagggctgcctggactgcctccatgatggtg gcctgctctgtattaggtgagtgttcaggaaaggtgagggcagggcagcccacagcttcacagtggcccagggaagcagg gcaggcaggctatgaggcctagtaggcatctgggccagactttgacactgaggccatggaatgggtggggctctgagaac agaccaaagtgatcatgggctgaaggctatgtccacagatccaaggcgggataggctgtgctgggcagtgatgtcagcca ggctccccagcgggactgggggtgtcaggggcagctctgtcccaggtggcagacactggtttcccctcctgctctcacaa ccggcctgttaccaggtgttgtctgagctgtggtgaggcttccctggtgacattcaggagcagggagcctgtgagtaagg gtgtatgcatctgccctgactgcctggccctgtggtcaaggatgggggaaggcagctctgcctgcagctccaccccattt ataaagcactgtggtgccttctgctggggcatgtgctgagtggtgcctcgcaggcactgccctcgggaagttcacaggct tatgtggaagctggtgggaatgggccaagaagagaggtgtcaggagccaggtattgggcaggtcccaggtctctgagcct cagtttcttcatctgtaggagggtggtgaccctgccctgctcagcttaccaggtacagatgtaagttttcagtgcagagg aaaagcagagaagttcccctcagatggccatacccccttgtcgctgtacccaactctccggtcctactttgtagctctca ggtgtcacatgtggatcctgccctaccatcccccttccctgtctagaaacgaggcctgctgagcttggagccatcccact ccctgctctcaagccgtctgctcctgggttagcctgtggctggcctggcctgattctacatagatgtgggtgtttctcca ctgctggggcagcagttgtccattctggggcctgggtcagctctcagctgtggccgttgtgcctgtgcttccccaggtcc tggtggtgactccaaccctgccctcacatatcccaagagcaggctgactgccttccccattcccacctttccagtaactg ctgcaagaacggacagacactgctgcagagaacttgccacggtgtttcatgctgtggctggtggttccaggctgcacgct ccattctaggaaagggtgaggcttcctgatcatcagtcttaacaggggactgtcctatgggtacctgtatacgctgccgg gagtggggcagagtggggttagagtagtgcctgctgcccattggggttgtgcgggttccttaagggctgtagtctgtgtg cgtgtctggttttttcctcctccttatcagtaatcagtcttgtataaccaggctggccctgcttcctgcctaggggctat cggtgtaccatctggagttgcaaatggggtgatagggcgtcagcggccttcccacacccaagcacttcctgacacccagc ccctcatctctagccaacctctggctcccctagggatcctggggctcaggcctcacgctccagcatccgggggctttgcc ttctggtgttgctcttctttgcaggtgccttggaacaggggtgcaacagagttcagaaagtgccatctgttgcatggata ccctgctgccaccctcgtccacctttctggggcagaacagttggatgggtctttatttaagaggacaaaagggagagaga atgcatagaggctgggtctggtgtcacgcctgtaatcccaacactttgggaggccaaggcaggtggatcccttgaggtca ggaggtcaagactagcctggccaacatggtgaaaccccgtctctactaaaaatacaaaaaaaaaaaaattagctgggcat ggcgggagatgcctgtaatcccagctactcgggaggctgaggcaggataatcacttgaacccaggaggcggaggttgcag tgagccaagatcacaccactgcactctagcctgggtgacagagggagactgtctcaaaaaaaaaaatttgcttagaattt gtctgtgtgaccctgggcaagtcatttcccctccttgggactcagttccttgcctgtgaacggggacagtgcttctccct tacagagctgttgtgagaattaaagtagaaaatgtacctatggtggttgttggtagtgaccagttcccccaaccctgact cccctgcaggatggggcctgggcccgggaatgggggatgggctggcagaggatgactgtcccagagaggagtcttctcgg cagatgtggagacctagctgagtcagaggccaggatctaagtttgagggtgttccttacaccctgcagccatgagtcttt ggctgagtcaaatggcctttctgagctcagttccttatcagtaaagcctggacagtggtccaggacgctggacactgtgt gagtgttaggacacaggacactgtgtgagtgcaggtggggacccatggagcactctgctggggagcaattcatggggagc acccctccagagagggatgatttgcacagggccctcagcccagtcccttgcaggctggaccttggagagtgaggccctga ggcgagacatgggcacctggctcctggcctgcatctgcatctgcacctgtgtctgcttgggagtctctgtcacaggggaa ggacaaggtgagggctgggcactaatgtctgtatgaggtgggtggagaactagggcatgtttgggggactgggttgtccg atgtcaagcctctagggaaaggtttggcccaaactgtgctggggcatgtcctctaggggtcagcctggacctcagtctct agtctccctacttttacctccctaccttcattccctggaccgactgtagtctcccttccttcactctcttgacgcctctc cagatctgacttgcccgtgtaccacaggtcagagcccatcacttcccaggcctcccagtgcttccctggacagattctgg gatcatttactggtgactgccctgctagggtgtcagctgtcagatcctccccaacccccgagctcagctctggcctgaag tacttaccgtgggctcctgatggtcactgtctccagggccaaggtctagaaccttcacctgcctcaccaacaacattctc aggatcgattgccactggtctgccccagagctgggacagggctccagcccctggctcctcttcaccaggtgagcatggag ggccatgcccacctggacagggatgagggtgagttccccaggattgaagcagctatgccaggacagtgtagcagccccgt ggtgctgacaaatgccctttccagcaaccaggctcctggcggcacacataagtgcatcttgcggggcagtgagtgcaccg tcgtgctgccacctgaggcagtgctcgtgccatctgacaatttcaccatcactttccaccactgcatgtctgggagggag caggtcagcctggtggacccggagtacctgccccggagacacggtgagcagcagctataggtctggggcggggccgcttg gcaagaacatcctggctgcttgggggtttggagcagggccttgcagcctgtgagtggcccagtgagtgttctcagtccca gccgagtgagatccagggctgggggcaggcttggcccttgggaggggagggcccatatggttactgcaggggcagggttt tggcaggaaataaacatgcacggctgctagttggggcaggggctggcacttgagtcatgtgaaatgcacttcagtcatac caggaaggactccaataagatgctgggaaaagcttccagcagcagactgtgaaggaaagggaaagcaagatttagaaacc acctagtctaggtgcagaggccagaggaagtcattgctgtcctgtcccgcctggggcttttgtggaccagtctcccagtg aggtgcctggtctgagagggccttgaccattccccttgggagtctttcagaccccagtcttgtgtgttctgactgacaca cccagacccatggggcttcagcctcacatggattcactctgttccagttaagctggacccgccctctgacttgcagagca acatcagttctggccactgcatcctgacctggagcatcagtcctgccttggagccaatgaccacacttctcagctatgag ctggccttcaagaagcaggaagaggcctgggaggtaacactttggctggctttccctgggggcctctctcctgggaacag cagtccagggtagactccccactctacatagggagatgtcaacttgtagtgatgagaagggaggaactagagcggggtgt gtgtgcacacacacatgctggcatgcagatgtgtatgctttatgtgtgtgtatgggagtagggtgagtgcgcctgtgtct ctgtgtgtgcacataagtgtggtgagtgtgcatgtatgtgtttatgtgtacacatatgtaactgtgcacactcatgtttg tgtgcccatgtttgtgtgtttatatgtaagtgtacatatgtgtgtgcctgtgccttgcatttgtgtgagtgtgcacatgg gcatgcctatgtgtatgagtgtgtatgtgagtgtggtgagttgcttctgtgcacacacttttgtttatgagtgtgcatgc aagtgtgatgagtgtgaaagtgttcctgtagacatgtttgcctgtgtgtgcatatgtgtatttgtgggcaaacgcagctg tgtctgtgagtgtgagtgtgccttctgtgtgtgtgtgtgcacgtgaatgtggtgagtgtgtctgtgtgttaacacaagtg tgttcaagagtgtgttatatgagcatataatgcatgtgtgtattctcgagggctgagggacccagccccaccttcaccac ctgctaactgtccccacccccacagcaggcccagcacagggatcacattgtcggggtgacctggcttatacttgaagcct ttgagctggaccctggcttta ccatgaggccaggctgcgtgtccagatggccacactggaggatgatgtggtagaggag gagcgttatacaggccagtggagtgagtggagccagcctgtgtgcttccaggctccccagagacaaggtgggcactgctg tggctgctgcacttccagcggagtctgggctgggcgtcttctcccctgttcacctcagccctgcaccctttcaccctcct gtaagcccctccccgaggcagccatgcctcagttgacccccttcctctgaaggtctgaggtctgtagggaggacagaaac acctgccaactctggggcttcctgggaacctgtagttagtggctgctgttaggagtgagggtggcagggctgcacaccag ggctgggctcctgcctggaggctggacatgacctcagtgtccttaatgggggctggactgacccttgcgcactgcagtgc tgagatggcccagggactttatgacccaccttgtggcagatgggaagagtgaggcccaggagtgtggttcacacaaggtc cttcagcaggtgacacaaacctccaaggcccatcacaaggtccttcagcaggtgacacaaaggtggaaggcccatcacaa accttccactttggcccagggcactaaagggcgcacctttgccaggtgggtttggggggagcctcctggcactgaggctg ctcacagccctgggcccttcctgtccacaggccctctgatcccaccctgggggtggccaggcaacacccttgttgctgtg tccatctttctcctgctgactggcccgacctacctcctgttcaagctgtcgcccaggtaggtggctgatgtgtgcgtgtg tgtacatgtgtgagcgggcaagagtgtgcatgttagtgtatgtgtgcagatgtgtgactgtgtgcatgtgtgagtgtgtg gtgggtgggccatcaagggccgcccttgtctggttcctcccctcccctctccactgcctggtcctggacggggtgggctt ttcgagtctccaccctggtccagaagagggttctcaagttgccaggggagagcagggaaggggggtctgaggcagaggct gaagataagggcagcttggtcccgaccagacccagagtcaccgagatcaagagccggaggtcctagtctcctgcctctgg aggagcttggtttgttcatttgttcacatgttctacgaaaggacagttggggcatctggtgtgctcaggaccctgttctc agaacaagatggacaagggccctccttaaataaaccgtcacgcctcatgcaccacatgtcaggttacaagacagggtgca ggggccatgtcaggccgcagatgtgaggaagagggtgtggggagaggggtgttgggtggggctaagtgggagggtgcttc gcttctccttggagcaaaggaaagtgtaaaactgtgtgacacaacctagtttatgttttgaggaatagattgctgggaca aggggacatgggggacctgctggaggccaatgggggccagtgaggtgcccacagggagacgatttgcatgagccagtgaa agaagtggagatagagaaaagtggagagaattgcagggtctcatgaggggaaatagaagggacatgtgggtggatgagat atgagtggtgacccctgaggtggggaaatgggggacagccttgcagggaggttggtgaagtctatttggacctgttgggt tggagccccaggtgacatccttgtgggagggtcagtggatccttggcagcaagtctggtgctcagggagacactgggtgg ggtgggagccacagaccttctgctgatggcaaagacagggttcctggaggtgctggctccctctgtgatctgaggaccca gctagtaactccccgttctgaacccgccatcgcagctcacgctgtaaaggacgcgcgcctcagtataaatcagttctatg cggccgttaggcaaggaggcccagttgggtcctgccctgagagtgggttggaatgtgatgagatgggagagaggcagtgg cagggacgaggtgggcggacctcctgctgatggaaggaagctcagcctctgcagtgacctcaggccacctgggtcgccat aggcctctgactggcctctcttggcctcagggtgaagagaatcttctaccagaacgtgccctctccagcgatgttcttcc agcccctctacagtgtacacaatgggaacttccaggtgtgtgcagagaccacagaaggacatggggggcaggggttgccc agagctctggcctgcccaagatgttggctttcatgagggttggcggccagtatgggaggcttgtcagtgcttggagcctt ttttgtatattcagtgaatttcaatttatacgcgtatctcaaatggggaaaaattagctttattttccattgctgatttc tttttgttctcaggtctctagttccattgttgattgaaaaaatgtaaatttctcataacttatctctgtcccctctggtt tgcagctttctgcacccaccatgtgcctcacctcctccttctgcgaaggtgtctgtcctgtggccatggggaagggtctg tggtgtgtgtgctgcccttggggctctcactgcctctgggctcctgctctgcctggtcccctggtctccccggatcacat gatggcaccacagctgaggagtgggctctgcacttcccccccttccacccatgttgggctcctacagcccaggcaccagt gagcaacttgggggttgcatcagcccctcccctccctgctgggctgttggttcatgccccctgggtgggaggagggggag agggagagctccagtgagtggtctctggtttttcccctcagactcctcactttgggcaaaggacaagaggcagtgagggc ccctccctggggtctgggccaagctgaccactcttctccagaatcttccctccctgtccccttcacactgtggctccagc ttactatgcagaaaaatccttttctctctcaatgaggagcgtagttttcaagatttttgtccaaaaatataatttgaacc atgaaccgggcatctggctcttggcagagtctccctctttccccaaggtggtagatgtgactgtcaggagcctgggcagc tgacgacaaggctgagcaggtcagattgtgactgtcccctggactgtcatcctgttgcgggcaccagctgttccctagag aactaggacacctgccacgggttatttagactgcgggtgaggatctggtgccataggttggtctccagggagcactgcag tgatggagggtgttgtgtgtgtgatgcatgggatggaggctcctggtcccaccaagggaacagcttccttttggaggcgg gggcctcctgtggccccacagaaggatccaggtctgctggccatagccgagtgctttgaaagtcaccagtcctgacagcg attcgtgtgtgtgtctgtgtgtgtgtgtgtgtgtttatgtgtctgtgtgtgttcgtgtgtgtgtctgtgtgtgtgtttgt gtgtgtatgtctgtgtgtgtgtgtttatgtgtgtgtgtctgtatgtgtttaagtctgtgtgtgtttgtgtgtgtgtgtct ctgtgtgtgtgtctg atctgtgtgtgtttgtgtctgtgtgtgtttgtgtgtgtgtctgtgtgtgtctgtgtgtgtgtct gtgtgtgtgtttatgtgtctgtgtatgtttgtgtgtgtgtttgtgtgtgtgtgtttgtgtttatgtgtgtatgtctgtgt gtgtctgtgtgtctgtgtgtgtatgtgtctgtgtgtgtttatgtgtctgtgtgtgttcgtgtgtgtgtctgtgtgtgtgt gtttgtgtgtgtatgtctgtgtgtgtgtgtgtttatgtgtgtgtgtctgtgtgtgtttatgtctgtgtgtgtttgtgtgt gtgtgtctcgtgtgtgtgtgtctgtgtgtatctgtgtgtgtttgtgtgtgtgtgtgtctctgtgtgtgtgtgtgtttgtg tatgtttgtgtgtgtgtgtgtgtgtgttgggaatgcccagtctctgcagctgctgaaaggccctgaggcacatgctgtca ggagctggctctgtcctgggcagatatcaccatctgtacctcggttcaggctgccgtgggcaccaggccctgtgctgggg gagtgctgaggagcctgaagggactcagggtcccgtgatgaggctgggctggcacatggaggaaagacagaatgtccaag acacaggcgctgcttggcctctgggtgtggacctcaggagggcttcctggaggaggagggatgctgggcttgccagaaag gaggcagctgctcccaggatgagttctgaacatgctacctgagcccttccctcctcccgtgctctgttccagacttggat gggggcccacggggccggtgtgctgttgagccaggactgtgctggcaccccacagggagccttggagccctgcgtccagg aggccactgcactgctcacttgtggcccagcgcgtccttggaaatctgtggccctggaggaggaacaggagggccctggg accaggctcccggggaacctgagctcagaggatgtgctgccagcagggtgtacggagtggagggtacagacgcttgccta tctgccacaggaggactgggcccccacgtccctgactaggccggctcccccagactcagagggcagcaggagcagcagca gcagcagcagcagcaacaacaacaactactgtgccttgggctgctatgggggatggcacctctcagccctcccaggaaac acacagagctctgggcccatcccagccctggcctgtggcctttcttgtgaccatcagggcctggagacccagcaaggagt tgcctgggtgctggctggtcactgccagaggcctgggctgcatgaggacctccagggcatgttgctcccttctgtcctca gcaaggctcggtcctggaca tctaggtccctgactcgccagatgcatcatgtccattttgggaaaatggactgaagttt ctggagcccttgtctgagactgaacctcctgagaaggggcccctagcagcggtcagaggtcctgtctggatggaggctgg aggctcccccctcaacccctctgctcagtgcctgtggggagcagcctctaccctcagcatcctggccacaagttcttcct tccattgtcccttttctttatccctgacctctctgagaagtggggtgtggtctctcagctgttctgccctcataccctta aagggccagcctgggcccagtggacacaggtaaggcaccatgaccacctggtgtgacctctctgtgccttactgaggcac ctttctagagattaaaaggggcttgatggctgttcccaaagtgttgatggctgggagaaggggccagaggaggagtgagg ggtggggtttgtccagccctgggctttccgggctctagagatagcatggtgtaggctcaatgacagttctggggacagca agttggaggttcaggggcagcttcaggacagcaggatggaggctcagggacaattcctgggaggccagtgccctcgttcc tccttgtcctcatcctcccccttgctccaggaaactgagagctgagcctggagcttccagacagtcagtgctgggggtga ccatccagcagtgatggtggcctgtgaagggtcctgcttctgtcctcagcctctcatggggtgggcttgtggaggagctg tggtctggagagagtggcagttggagcagaacgtgcctgcgtttgtttcctagggctgtcgtaacaaagtgccacaaaat ggttagcttagaaccacagagatttgttgtctcacaattctgaagtccagaagttggaaataaagatgttggcagtgttc ccaaccacatgttcttgggctcccatgaaacagaagttgatattaggccaaggaagcttcccagacaagactttattaag tcttatgccccgaaagtttgggcagaagagagacggtgcaggaggaagaattcttggctgactccccaaggggaatgcat tgtggtgtcttaaggagggtgacatacataatttatgagctacatgagtgtcattgcacatatggggtggagcgaagggt gctcagacgcatgctaacacatacgttgcatgatcagaaaatggcagataagcccctccctgggtgaggactttagtatt atcataagaccagggtcattctcctggccttgtgcacaagcaggtgatggagtcaactcccgtcagtaagacttatggcg ggatgctgcttatcttagtttatttcagacagttggcaaggtctggccagcgagtatggcacctggagggtggtgctgca aggtctagtggtcagcgggcacgtatggaacaatacgttagtgggggtgggccgagtcccatttatactctctcagcagg gccatgctccctctgaaggcactagggaaggattagtttcaggcctctcttcagcttctgttagtttcttggcttgtgac accaaagctgtaatctttcttttgttttgtttttgtgacggagttttgctcttgttgcccaggctggagtgcaatggcac aatctcggctcactgcaacctcctcctcccaggtttaagcaattcttctgcctcagcctttggagtagctgtgattacaa ggcacctgctaccacgcctggctagtttttgtatttttagtagagacggtgtttcgctatgttggccaggctggtctcaa actcctgatatcaagtgatccgtctgtctctgcctcccaaagtgttgggattacaggcatgagccaccgtgcctggccaa agttccagtctttacagggatttttccttgtgtgcatttctgtgtccaaatttcccctttttaaaatcacaataatagtg aattaaggctggccctaacgatttaatcttaacttgatcatctgcaaagacactat tccatataaggtcacattcacag ctactggggttaggacttcaacctagagggcctgacttctggcccaacacatcatggcccatcccagcatgccccatccc cttcctgggtgccccaggcagatcacaggagggcctgactgctgggctttgggctgacattgggatcatctgcctagtta gggctgtgaccagactgagataggaggtgggacctgactcctgaggcagggcttgaactctggaccagattacagactag ctgaaacaggcaaaagcacccctccataagacacacccactggtgccaagtgagtttgccgttctcatggtaacagctgg aaattactgcccctttccatggcaatgacctgaaagttaccaccccttttctagaaatttctaaataacctcctccttaa tttgtatatagttacaagtgggtataaatatgtgtgcagaactgcctctgagctgctactctgggctgactgcctatggg gcatccctgctccataaggagcagtacctctgctgccactgtgcacagctgcttaaataaaagttgctctctaataccac cgactcgcccttgaattctttcctgggtgaagc (SEQ ID NO: 11934) atatatatatgcataatagtctctgtgtaacagtaagtggatgcagtaactggtgtgagggcaacttggagagtgtgctt ggaggcacagagatgctcagggctgcctggactgcctccatgatggtggcctgctctgtattaggtgagtgttcaggaaa ggtgagggcagggcagcccacagcttcacagtggcccagggaagcagggcaggcaggctatgaggcctagtaggcatctg ggccagactttgacactgaggccatggaatgggtggggctctgagaacagacccaagtgatcatgggctgaaggctatgt ccacagatccaaggcgggataggctgtactgggcagtgatgtcagccaggctccccagcgggactgggggtgtcaggggc agctctgtcccaggtggcagacactggtttcccctcctgctctcacaaccggcctgttaccaggtgttgtctgagctgtg gtgaggcttccctggtgacattcaggagcagggagcctgcgagtaagggtgtatgcatctgccctgactgcctggccctg tggtcaaggatgggggaaggcagctctgcctgcagctccaccccatttataaagcactgtggtgccttctgctgggacat gtgctgagtggtgcctcgcaggcactgccctcgggaagttcacaggcttatgtggaagctggtgggaatgggccaagaag agaggtgtcaggagccaggtattgggcaggtcccaggtctctgagcctcagtttcttcatctgtaggagggtggtgaccc tgccctgctcagcttaccaggtacagatgtaagttttcagtgcagaggaaaagcagagaacttcccctcagatggccata cccccttgtcgctgtacccaactctccggtcctactttgtagctctcaggtgtcacatgtggatcctgccctaccatccc ccttgccctgtctagaaacgaggcctgctgagcttggaaccatcccactccctgctctcaagccgtctgctcctgggtta gcctgtggctgacctggcctgattctacatagatgtgggtgtttctccactgctggggcagcagttgtccattctggggc ctgggtcagctctcagctgtggccgttgtgcctgtgcttccccaggtcctggtggtgactccaaccctgccctcacatat cccaagagcaggctgactgccttccccattcccacctttccagtaactgctgcaagaacggacagacactgctgcagaga acttgccacggtgtttcatgctgtggctggtggttccaggctgcacgctccattctaggaaagggtgaggcttcctgatc atcagtcttaacaggggactgtcctatgggtacctgtatacgctgccgggagtggggcagagtggggttagagtagtgcc tgctgcccattggggttgtgcgggttccttaagggctgtagtctgtgtgcgtgtctggttttttcctcctccttatcagt aatcagtcttgtataaccaggctggccctgcttcctgcctaggggctatcggtgtaccatctggagttgcaaatggggtg atagggcgtcagcggccttcccacacccaagcacttcctgacacccagcccctcatctctagccaacctctggctcccct agggatcctggggctcaggcctcacgctccagcatccgggggctttgcccttctggtgttgctcttctttgcaggtgcct tggaacaggggtgcaacagagttcagaaagtgccatctgttgcatggataccctgctgccaccctcgtccacctttctgg ggcagaacagttggatgggtctttatttaagaggacaaaagggagagagaatgcatagaggctgggtctggtggctcacg cctgtaatcccaacactttgggaggccaaggcaggtggatcccttgaggtcaggaggtcaagactagcctggccaacatg gtgaaaccccgtctctactaaaaatacaaaaaaaaaaaaattagctgggcatggcgggagatgcctgtaatcccagctac tcgggaggctgaggcaggataatcacttgaacccaggaggcggaggttgcagtgagccaagatcacaccactgcactcta gcctgggtgacagagggagactgtctcaaaaaaaaaaatttgcttagaatttgtctgtgtgaccctgggcaagtcatttc ccctccttgggactcagttccttgcctgtgaacggggacagtgcttctcccttacagagctgttgtgagaattaaagtag aaaatgtacctatggtggttgttggtagtgaccagttcccccaaccctgactcccctgcaggatggggcctgggcccggg aatgggggatgggctggcagaggatgactgtcccagagaggagtcttctcggcagatgtggagacctagctgagtcagag gccaggatctaagtttgagggtgttccttacaccctgcagccatgagtctttggctgagtcaaatggcctttctgagctc agttccttatcagtaaagcctggacagtggtccaggacgctggacactgtgtgagtgttaggacacaggacactgtgtga gtgcaggtggggacccatggagcactctgctggggagcaattcatggggagcacccctccagagagggatgatttgcaca gggccctcagcccagtcccttgcaggctggaccttggagagtgaggccctgaggcgagacatgggcacctggctcctggc ctgcatctgcggatccatgcccagaattattcacgaaattcacttaaaatagcatatatgcttgaacccaggagtctgag gctgcagcgagctatgatcatgtcactgcactccagcccagcctgggcgacagagcaagactctgtgtctaaagaaatga aaataaaaataaataaaatagcatatacaggcaacaatccaaatgttcattgcagaaattatgattattattgtttttct tttagaggcagggtgtcactctgttgcccagactaatcttgacctcctgtgatcctcaagagatcctccggtctctgctt cccaaagttcttggattacaggtgtgaggcactgggcctagacattgcagggattattaaaccatggtgcatactaccat taaaggtatgaggtaggttttatatgctgacctagaaagatggtgcaacaccataggggaacaagaaggctgcaaagtgg cagcacagcaggagtctttaagaaataggtatttgtttcagcttaagaagtgtctggctgggcgtggtggctcacacctg taatcccagcacttagggaggcttaggtgggcggatcacttgaggttaggagttcaagaccagcccagtcaacaccggtg aaaccccatctctactaaaaatacaaagaaattagctgggcttggtggcaggtggctgtaatcccagctactcaggagct gaggcaggagaatcatctgaacccgggaggccgaggttgcagtgagcctagatcgcaccactgcactccagcctgggtga cagagtaagactcggtcaaaaaaaaaaaaaaaaaagaccgggtgcgaggtctctcgcctgtaatcccagcactttgggag gcctaggcaggaggatcacaaggtcaggagatcgagaccatcctggccaacatggtgaaaccccatctctactaaaatac aaaaattagccgggtgtgatggcacacgcctgtagtcccagctactcaggaggctgaggcaggggaatcgcttgaaacca ggaggtggaggctgcagtgagccgagatcacgccactgcactccagcctggcgacagagcaagactccatctcaaaaaag aaaagaaaacaaacaaacaaacaaaatccccaaaaagcaaaagtgtctgcatggacttgtgcctaactactcacagtggc tacttcttgggggaggtgaaaggggaccctgttaaagaatttttcttctgtattgtttttcttcaactgagtctgcatta attttatatttaatactctccccacccctgatgctcacaggttgctttagctggtggaaggagaacctgcacctctggtt ttggcaaagtgtagaaggggacaagggcactgctctgcacctgcacaggttcttgcctcctggggtcagtttaatgaatc tcagtggtgtttcttgggaagaacacagtggacactcacttgccagtcagtagacaaatcactgaagtccatgtctggca gttctcaatgtcatggggactgtaaggttgtcatgtctcacagttccctgacttagaagattagtggtgacagacacttc tcagctctgctcgggagagcagctctgtaatgcgcttgtggtttcagatgtgggcggcctgtgtgaacctgtcgtgcaaa gctcacgtcaccaactgctgcagttatctcctgaatcaggctgagggtctttgctgtgcacccagagatagttgggtgac aaatcacctccaggttggggatgcctcagacttgtgatgggactgggcagatgcatctgggaaggtgagtctgtgctttg ggcttcccaacctctcaagtcagcatgaaattcagaaggcagagagggacatgtggccctccaactcggggcccagggag ccactgtggcatttgagagcgccaccctagctttacctcctctggtgtcctggccttgtgtatctcttagagatggcaaa atttgcagccctgacctcaaggattacaaactaatttccagtcctgtaggggtcatgggttctgctgtggccagtgtggc actgagtttgtcaggcagaatttctaattatggaaggaactctgcttcctcagtgattgaactgacctttgtgggggtgc ctttgtggggtgagaatgggcatacttgggcctcagttgtgatggccatggggtggagctgaggtctaggcccagggctg ggaaagcttctaccaaccccgaggcatttgggtgttttagggcagaagaggagccaggaggatgggtatgccccactgga gctgtgtgtggggcagcaggtgagggtgggattccagagggagggtcaacccagccaagcagaggaaggggaggagaggg tttgttttggaaagaacatcaccctctcagtttcctggggtctggatagcctgttcttgtgatgagctggaggatgtggg ccctgcttggatcctcctctcccctccctgcccccattttctcttcctgtgatttatgctgttctgggctcaccctcttc ccagagctctcacgctacagctgacaggcagggcaggcgttttaattattattaatttttttttgagacagagtttgaga cagtatcaagagtgggt tcctctcagcgtgtcttcaagtagcatcccagagccccgctcctgggtacccacaacatgaa caccgtccagaagcaagggcagcctctgcaggtggggcgggggttggaaaacatttatcaaacggttgagttgggtgcag gggatgcaacatgatcaaacagggtcttgcctccaggagcctcatgtagggacaacgcacagtgatgaccttcaactgca gtggggcagcaaggctgtgggaggggtgttttgggcagagcaggcgacgtgggtacctcttcaccaagacagcaggaaga gcacggacatcattttcccgtctcacctccagactcccaggggactgtgccaatatcctcactggagccctgcccatggc cactgctcaacccttgggccctgtcagttcagggctgtgcagaaggagagttgcctgtgctcaggctcaggggttccgtc cagctaaggaggcctactaggggactggggaaaggcctcatgaaggaccaggcctgtgatggggagggaagatggcagag gggacagtgggaagcagagcagcaggggtctcctccacgcctctctgtacttctcccacccacccttgcctgctcccctc tgccctgggtatgtgcccttgtccacccaacacctctgcagtgccaagtccagccctgacttcttcctgagctgtggccc agcgttcccacaggcatttacctcacggatgcagcactgcccctcatcctcttctctgaaagtgtgtgggaaatgcttct tggtgccatctctctcccaccctgccttccctgcaccttctctatgaggtgtctgttgtctctgtacttgcctccagctg gcctttcagaccccatccctccctgcctcctgcccatccctacccctgtcagcaccttacatactctgtgcccaacagca ttggggattcccactgtgctgaaggaagtcctcatgtggtccagagagggagctggcccctgctcccatttccagcacca ttttctggcacaggctccatgtccccaggctccagctgcttctggggtaccaaggtctgcatttcttcctcttcccccag cagacagaagaccttgctggacaggtgtccacttcaatagtaacttctgaggctgccagcctcctgaatggtccagaaga accagacccttccccgcccccattaaaaaagacaaaatatggccaggcatgttggctcatgcctgacatcccagcacttt gggaggccaaagcaggtgaatcacttgaggccaggagtacgagaccagcctgacaaacatggtgaaaccctgtgtctact aaaaatacaaaaattagccaggcgtggtgactcatgcttgtaaatgcttgtaatcccagctacttgggaggctgaagcag gaggatcacttgaactcgggaggcagaggttgcagtgagccgagatcacgccactgtgttccagcctgagcgacagagcg acactccgtctaaaaaaaaaaaatatatatatatatacacacatatatatatgcataatagtctctgtgtaacagtaagt ggatgcagtaactggtgtgagggcaacttggagagtgtgcttggaggcacagagatgctcagggctgcctggactgcctc catgatggtggcctgctctgtattaggtgagtgttcaggaaaggtgagggcagggcagcccacagcttcacagtggccca gggaagcagggcaggcaggctatgaggcctagtaggcatctgggccagactttgacactgaggccatggaatgggtgggg ctctgagaacagaccaaagtgatcatgggctgaaggctatgtccacagatccaaggcgggataggctgtgctgggcagtg atgtcagccaggctccccagcgggactgggggtgtcaggggcagctctgtcccaggtggcagacactggtttcccctcct gctctcacaaccggcctgttaccaggtgttgtctgagctgtggtgaggcttccctggtgacattcaggagcagggagcct gtgagtaagggtgtatgcatctgccctgactgcctggccctgtggtcaaggatgggggaaggcagctctgcctgcagctc caccccatttataaagcactgtggtgccttctgctggggcatgtgctgagtggtgcctcgcaggcactgccctcgggaag ttcacaggcttatgtggaagctggtgggaatgggccaagaagagaggtgtcaggagccaggtattgggcaggtcccaggt ctctgagcctcagtttcttcatctgtaggagggtggtgaccctgccctgctcagcttaccaggtacagatgtaagttttc agtgcagaggaaaagcagagaagttcccctcagatggccatacccccttgtcgctgtacccaactctccggtcctacttt gtagctctcaggtgtcacatgtggatcctgccctaccatcccccttccctgtctagaaacgaggcctgctgagcttggag ccatcccactccctgctctcaagccgtctgctcctgggttagcctgtggctggcctggcctgattctacatagatgtggg tgtttctccactgctggggcagcagttgtccattctggggcctgggtcagctctcagctgtggccgttgtgcctgtgctt ccccaggtcctggtggtgactccaaccctgccctcacatatcccaagagcaggctgactgccttccccattcccaccttt ccagtaactgctgcaagaacggacagacactgctgcagagaacttgccacggtgtttcatgctgtggctggtggttccag gctgcacgctccattctaggaaagggtgaggcttcctgatcatcagtcttaacaggggactgtcctatgggtacctgtat acgctgccgggagtggggcagagtggggttagagtagtgcctgctgcccattggggttgtgcgggttccttaagggctgt agtctgtgtgcgtgtctggttttttcctcctccttatcagtaatcagtcttgtataaccaggctggccctgcttcctgcc taggggctatcggtgtaccatctggagttgcaaatggggtgatagggcgtcagcggccttcccacacccaagcacttcct gacacccagcccctcatσtctagccaacctctggctcccctagggatcctggggctcaggcctcacgctccagcatccgg gggctttgccttctggtgttgctcttctttgcaggtgccttggaacaggggtgcaacagagttcagaaagtgccatctgt tgcatggataccctgctgccaccctcgtccacctttctggggcagaacagttggatgggtctttatttaagaggacaaaa gggagagagaatgcatagaggctgggtctggtgtcacgcctgtaatcccaacactttgggaggccaaggcaggtggatcc cttgaggtcaggaggtcaagactagcctggccaacatggtgaaaccccgtctctactaaaaatacaaaaaaaaaaaaatt agctgggcatggcgggagatgcctgtaatcccagctactcgggaggctgaggcaggataatcacttgaacccaggaggcg gaggttgcagtgagccaagatcacaccactgcactctagcctgggtgacagagggagactgtctcaaaaaaaaaaatttg cttagaatttgtctgtgtgaccctgggcaagtcatttcccctccttgggactcagttccttgcctgtgaacggggacagt gcttctcccttacagagctgttgtgagaattaaagtagaaaatgtacctatggtggttgttggtagtgaccagttccccc aaccctgactcccctgcaggatggggcctgggcccgggaatgggggatgggctggcagaggatgactgtcccagagagga gtcttctcggcagatgtggagacctagctgagtcagaggccaggatctaagtttgagggtgttccttacaccctgcagcc atgagtctttggctgagtcaaatggcctttctgagctcagttccttatcagtaaagcctggacagtggtccaggacgctg gacactgtgtgagtgttaggacacaggacactgtgtgagtgcaggtggggacccatggagcactctgctggggagcaatt catggggagcacccctccagagagggatgatttgcacagggccctcagcccagtcccttgcaggctggaccttggagagt gaggccctgaggcgagacatgggcacctggctcctggcctgcatctgcatctgcacctgtgtctgcttgggagtctctgt cacaggggaaggacaaggtgagggctgggcactaatgtctgtatgaggtgggtggagaactagggcatgtttgggggact gggttgtccgatgtcaagcctctagggaaaggtttggcccaaactgtgctggggcatgtcctctaggggtcagcctggac ctcagtctctagtctccctacttttacctccctaccttcattccctggaccgactgtagtctcccttccttcactctctt gacgcctctccagatctgacttgcccgtgtaccacaggtcagagcccatcacttcccaggcctcccagtgcttccctgga cagattctgggatcatttactggtgactgccctgctagggtgtcagctgtcagatcctccccaacccccgagctcagctc tggcctgaagtacttaccgtgggctcctgatggtcactgtctccagggccaaggtctagaaccttcacctgcctcaccaa caacattctcaggatcgattgccactggtctgccccagagctgggacagggctccagcccctggctcctcttcaccaggt gagcatggagggccatgcccacctggacagggatgagggtgagttccccaggattgaagcagctatgccaggacagtgta gcagccccgtggtgctgacaaatgccctttccagcaaccaggctcctggcggcacacataagtgcatcttgcggggcagt gagtgcaccgtcgtgctgccacctgaggcagtgctcgtgccatctgacaatttcaccatcactttccaccactgcatgtc tgggagggagcaggtcagcctggtggacccggagtacctgccccggagacacggtgagcagcagctataggtctggggcg gggccgcttggcaagaacatcctggctgcttgggggtttggagcagggccttgcagcctgtgagtggcccagtgagtgtt ctcagtcccagccgagtgagatccagggctgggggcaggcttggcccttgggaggggagggcccatatggttactgcagg ggcagggttttggcaggaaataaacatgcacggctgctagttggggcaggggctggcacttgagtcatgtgaaatgcact tcagtcataccaggaaggactccaataagatgctgggaaaagcttccagcagcagactgtgaaggaaagggaaagcaaga tttagaaaccacctagtctaggtgcagaggccagaggaagtcattgctgtcctgtcccgcctggggcttttgtggaccag tctcccagtgaggtgcctggtctgagagggccttgaccattccccttgggagtctttcagaccccagtcttgtgtgttct gactgacacacccagacccatggggcttcagcctcacatggattcactctgttccagttaagctggacccgccctctgac ttgcagagcaacatcagttctggccactgcatcctgacctggagcatcagtcctgccttggagccaatgaccacacttct cagctatgagctggccttcaagaagcaggaagaggcctgggaggtaacactttggctggctttccctgggggcctc ctc ctgggaacagcagtccagggtagactccccactctacatagggagatgtcaacttgtagtgatgagaagggaggaactag agcggggtgtgtgtgcacacacacatgctggcatgcagatgtgtatgctttatgtgtgtgtatgggagtagggtgagtgc gcctgtgtctctgtgtgtgcacataagtgtggtgagtgtgcatgtatgtgtttatgtgtacacatatgtaactgtgcaca ctcatgtttgtgtgcccatgtttgtgtgtttatatgtaagtgtacatatgtgtgtgcctgtgccttgcatttgtgtgagt gtgcacatgggcatgcctatgtgtatgagtgtgtatgtgagtgtggtgagttgcttctgtgcacacacttttgtttatga gtgtgcatgcaagtgtgatgagtgtgaaagtgttcctgtagacatgtttgcctgtgtgtgcatatgtgtatttgtgggca aacgcagctgtgtctgtgagtgtgagtgtgccttctgtgtgtgtgtgtgcacgtgaatgtggtgagtgtgtctgtgtgtt aacacaagtgtgttcaagagtgtgttatatgagcatataatgcatgtgtgtattctcgagggctgagggacccagcccca ccttcaccacctgctaactgtccccacccccacagcaggcccagcacagggatcacattgtcggggtgacctggcttata cttgaagcctttgagctggaccctggctttatccatgaggccaggctgcgtgtccagatggccacactggaggatgatgt ggtagaggaggagcgttatacaggccagtggagtgagtggagccagcctgtgtgcttccaggctccccagagacaaggtg ggcactgctgtggctgctgcacttccagcggagtctgggctgggcgtcttctcccctgttcacctcagccctgcaccctt tcaccctcctgtaagcccctccccgaggcagccatgcctcagttgacccccttcctctgaaggtctgaggtctgtaggga ggacagaaacacctgccaactctggggcttcctgggaacctgtagttagtggctgctgttaggagtgagggtggcagggc tgcacaccagggctgggctcctgcctggaggctggacatgacctcagtgtccttaatgggggctggactgacccttgcgc actgcagtgctgagatggcccagggactttatgacccaccttgtggcagatgggaagagtgaggcccaggagtgtggttc acacaaggtccttcagcaggtgacacaaacctccaaggcccatcacaaggtccttcagcaggtgacacaaaggtggaagg cccatcacaaaccttccactttggcccagggcactaaagggcgcacctttgccaggtgggtttggggggagcctcctggc actgaggctgctcacagccctgggcccttcctgtccacaggccctctgatcccaccctgggggtggccaggcaacaccct tgttgctgtgtccatctttctcctgctgactggcccgacctacctcctgttcaagctgtcgcccaggtaggtggctgatg tgtgcgtgtgtgtacatgtgtgagcgggcaagagtgtgcatgttagtgtatgtgtgcagatgtgtgactgtgtgcatgtg tgagtgtgtggtgggtgggccatcaagggccgcccttgtctggttcctcccctcccctctccactgcctggtcctggacg gggtgggcttttcgagtctccaccctggtccagaagagggttctcaagttgccaggggagagcagggaaggggggtctga ggcagaggctgaagataagggcagcttggtcccgaccagacccagagtcaccgagatcaagagccggaggtcctagtctc ctgcctctggaggagcttggtttgttcatttgttcacatgttctacgaaaggacagttggggcatctggtgtgctcagga ccctgttctcagaacaagatggacaagggccctccttaaataaaccgtcacgcctcatgcaccacatgtcaggttacaag acagggtgcaggggccatgtcaggccgcagatgtgaggaagagggtgtggggagaggggtgttgggtggggctaagtggg agggtgcttcgcttctccttggagcaaaggaaagtgtaaaactgtgtgacacaacctagtttatgttttgaggaatagat tgctgggacaaggggacatgggggacctgctggaggccaatgggggccagtgaggtgcccacagggagacgatttgcatg agccagtgaaagaagtggagatagagaaaagtggagagaattgcagggtctcatgaggggaaatagaagggacatgtggg tggatgagatatgagtggtgacccctgaggtggggaaatgggggacagccttgcagggaggttggtgaagtctatttgga cctgttgggttggagccccaggtgacatccttgtgggagggtcagtggatccttggcagcaagtctggtgctcagggaga cactgggtggggtgggagccacagaccttctgctgatggcaaagacagggttcctggaggtgctggctccctctgtgatc tgaggacccagctagtaactccccgttctgaacccgccatcgcagctcacgctgtaaaggacgcgcgcctcagtataaat cagttctatgcggccgttaggcaaggaggcccagttgggtcctgccctgagagtgggttggaatgtgatgagatgggaga gaggcagtggcagggacgaggtgggcggacctcctgctgatggaaggaagctcagcctctgcagtgacctcaggccacct gggtcgccataggcctctgactggcctctcttggcctcagggtgaagagaatcttctaccagaacgtgccctctccagcg atgttcttccagcccctctacagtgtacacaatgggaacttccaggtgtgtgcagagaccacagaaggacatggggggca ggggttgcccagagctctggcctgcccaagatgttggctttcatgagggttggcggccagtatgggaggcttgtcagtgc ttggagccttttttgtatattcagtgaatttcaatttatacgcgtatctcaaatggggaaaaattagctttattttccat tgctgatttctttttgttctcaggtctctagttccattgttgattgaaaaaatgtaaatttctcataacttatctctgtc ccctctggtttgcagctttctgcacccaccatgtgcctcacctcctccttctgcgaaggtgtctgtcctgtggccatggg gaagggtctgtggtgtgtgtgctgcccttggggctctcactgcctctgggctcctgctctgcctggtcccctggtctccc cggatcacatgatggcaccacagctgaggagtgggctctgcacttcccccccttccacccatgttgggctcctacagccc aggcaccagtgagcaacttgggggttgcatcagcccctcccctccctgctgggctgttggttcatgccccctgggtggga ggagggggagagggagagctccagtgagtggtctctggtttttcccctcagactcctcactttgggcaaaggacaagagg cagtgagggcccctccctggggtctgggccaagctgaccactcttctccagaatcttccctccctgtccccttcacactg tggctccagcttactatgcagaaaaatccttttctctctcaatgaggagcgtagttttcaagatttttgtccaaaaatat aatttgaaccatgaaccgggcatctggctcttggcagagtctccctctttccccaaggtggtagatgtgactgtcaggag cctgggcagctgacgacaaggctgagcaggtcagattgtgactgtcccctggactgtcatcctgttgcgggcaccagctg ttccctagagaactaggacacctgccacgggttatttagactgcgggtgaggatctggtgccataggttggtctccaggg agcactgcagtgatggagggtgttgtgtgtgtgatgcatgggatggaggctcctggtcccaccaagggaacagcttcctt ttggaggcgggggcctcctgtggccccacagaaggatccaggtctgctggccatagccgagtgctttgaaagtcaccagt cctgacagcgattcgtgtgtgtgtctgtgtgtgtgtgtgtgtgtttatgtgtctgtgtgtgttcgtgtgtgtgtctgtgt gtgtgtttgtgtgtgtatgtctgtgtgtgtgtgtttatgtgtgtgtgtctgtatgtgtttaagtctgtgtgtgtttgtgt gtgtgtgtctctgtgtgtgtgtctgtatctgtgtgtgtttgtgtctgtgtgtgtttgtgtgtgtgtctgtgtgtgtctgt gtgtgtgtctgtgtgtgtgtttatgtgtctgtgtatgtttgtgtgtgtgtttgtgtgtgtgtgtttgtgtttatgtgtgt atgtctgtgtgtgtctgtgtgtctgtgtgtgtatgtgtctgtgtgtgtttatgtgtctgtgtgtgttcgtgtgtgtgtct gtgtgtgtgtgtttgtgtgtgtatgtctgtgtgtgtgtgtgtttatgtgtgtgtgtctgtgtgtgtttatgtctgtgtgt gtttgtgtgtgtgtgtctcgtgtgtgtgtgtctgtgtgtatctgtgtgtgtttgtgtgtgtgtgtgtctctgtgtgtgtg tgtgtttgtgtatgtttgtgtgtgtgtgtgtgtgtgttgggaatgcccagtctctgcagctgctgaaaggccctgaggca catgctgtcaggagctggctctgtcctgggcagatatcaccatctgtacctcggttcaggctgccgtgggcaccaggccc tgtgctgggggagtgctgaggagcctgaagggactcagggtcccgtgatgaggctgggctggcacatggaggaaagacag aatgtccaagacacaggcgctgcttggcctctgggtgtggacctcaggagggcttcctggaggaggagggatgctgggct tgccagaaaggaggcagctgctcccaggatgagttctgaacatgctacctgagcccttccctcctcccgtgctctgttcc agacttggatgggggcccacggggccggtgtgctgttgagccaggactgtgctggcaccccacagggagccttggagccc tgcgtccaggaggccactgcactgctcacttgtggcccagcgcgtccttggaaatctgtggccctggaggaggaacagga gggccctgggaccaggctcccggggaacctgagctcagaggatgtgctgccagcagggtgtacggagtggagggtacaga cgcttgcctatctgccacaggaggactgggcccccacgtccctgactaggccggctcccccagactcagagggcagcagg agcagcagcagcagcagcagcagcaacaacaacaactactgtgccttgggctgctatgggggatggcacctctcagccct cccaggaaacacacagagctctgggcccatcccagccctggcctgtggcctttcttgtgaccatcagggcctggagaccc agcaaggagttgcctgggtgctggctggtcactgccagaggcctgggctgcatgaggacctccagggcatgttgctccct tctgtcctcagcaaggctcggtcctggacattctaggtccctgactcgccagatgcatcatgtccattttgggaaaatgg actgaagtttctggagcccttgtctgagactgaacctcctgagaaggggcccctagcagcggtcagaggtcctgtctgga tggaggctggaggctcccccctcaacccctctgctcagtgcctgtggggagcagcctctaccctcagcatcctggccaca agttcttccttccattgtcccttttcttt tccctgacctctctgagaagtggggtgtggtctctcagctgttctgccct catacccttaaagggccagcctgggcccagtggacacaggtaaggcaccatgaccacctggtgtgacctctctgtgcctt actgaggcacctttctagagattaaaaggggcttgatggctgttcccaaagtgttgatggctgggagaaggggccagagg ^aggagtgaggggtggggtttgtccagccctgggctttccgggctctagagatagcatggtgtaggctcaatgacagttct ggggacagcaagttggaggttcaggggcagcttcaggacagcaggatggaggctcagggacaattcctgggaggccagtg ccctcgttcctccttgtcctcatcctcccccttgctccaggaaactgagagctgagcctggagcttccagacagtcagtg ctgggggtgaccatccagcagtgatggtggcctgtgaagggtcctgcttctgtcctcagcctctcatggggtgggcttgt ggaggagctgtggtctggagagagtggcagttggagcagaacgtgcctgcgtttgtttcctagggctgtcgtaacaaagt gccacaaaatggttagcttagaaccacagagatttgttgtctcacaattctgaagtccagaagttggaaataaagatgtt ggcagtgttcccaaccacatgttcttgggctcccatgaaacagaagttgatattaggccaaggaagcttcccagacaaga ctttattaagtcttatgccccgaaagtttgggcagaagagagacggtgcaggaggaagaattcttggctgactccccaag gggaatgcattgtggtgtcttaaggagggtgacatacataatttatgagctacatgagtgtcattgcacatatggggtgg agcgaagggtgctcagacgcatgctaacacatacgttgcatgatcagaaaatggcagataagcccctccctgggtgagga ctttagtattatcataagaccagggtcattctcctggccttgtgcacaagcaggtgatggagtcaactcccgtcagtaag acttatggcgggatgctgcttatcttagtttatttcagacagttggcaaggtctggccagcgagtatggcacctggaggg tggtgctgcaaggtctagtggtcagcgggcacgtatggaacaatacgttagtgggggtgggccgagtcccatttatactc tctcagcagggccatgctccctctgaaggcactagggaaggattagtttcaggcctctcttcagcttctgttagtttctt ggcttgtgacaccaaagctgtaatctttcttttgttttgtttttgtgacggagttttgctcttgttgcccaggctggagt gcaatggcacaatctcggctcactgcaacctcctcctcccaggtttaagcaattcttctgcctcagcctttggagtagct gtgattacaaggcacctgctaccacgcctggctagtttttgtatttttagtagagacggtgtttcgctatgttggccagg ctggtctcaaactcctgatatcaagtgatccgtctgtctctgcctcccaaagtgttgggattacaggcatgagccaccgt gcctggccaaagttccagtctttacagggatttttccttgtgtgcatttctgtgtccaaatttcccctttttaaaatcac aataatagtgaattaaggctggccctaacgatttaatcttaacttgatcatctgcaaagacactatttccatataaggtc acattcacagctactggggttaggacttcaacctagagggcctgacttctggcccaacacatcatggcccatcccagcat gccccatccccttcctgggtgccccaggcagatcacaggagggcctgactgctgggctttgggctgacattgggatcatc tgcctagttagggctgtgaccagactgagataggaggtgggacctgactcctgaggcagggcttgaactctggaccagat tacagactagctgaaacaggcaaaagcacccctccataagacacacccactggtgccaagtgagtttgccgttctcatgg taacagctggaaattact^'gcccctttccatggcaatgacctgaaagttaccaccccttttctagaaatttctaaataacc tcctccttaatttgtatatagttacaagtgggtataaatatgtgtgcagaactgcctctgagctgctactctgggctgac tgcctatggggcatccctgctccataaggagcagtacctctgctgccactgtgcacagctgcttaaataaaagttgctct ctaataccaccgactcgcccttgaattctttcctgggtgaagc (SEQ ID NO:11935) aattcagaactcctcagccccccaagaaaaaaatatccccgtggaaattcctttttaatgaccgaggcgggggaaatatg cgtctctggatggccagtgactcgcagcccccttccccgataggaagggcctgcgcgtccggggacccttcgcttcccct tctgctgcgcgacctccctggcccctcggagatctccatggcgacgccgcgcgcgccccacaacaggaaagccttaggcg gcgcggcttggtgctcggagacttaagagtacccagcccctcgacgtggtggatgtcgagtcttggggtcacacgcacag gcggtggccaagcaaacacccgctcatatttagtgcatgagcctgggttcgagttgccggagcctcgcgcgtagggcagg ggttcgagcgccccttctccctgcctcgcctctgcgcctgggggctgctgcctcagtttcccagcgacaggcagggattt cgagcgtccccctcccctccctcgtcaagatccaagctagctgccteagtttccccgcggagcctgggacgccagcggag gggctcggcgcgtagggatcacgcagcttccttcctttttctgggagctgtaaagacgcctccgccaacgccgaaagggg aagcgaggaggccgccggggtgagtgccctcgggtgtagagagaggacgccgatttccccggacgtggtgagaccgcgct tcgtcactcccacggttagcggtcgccgggaggtgcctggctctgctctggccgcttctcgagaaatgcccgtgtcagct aggtgtggacgtgacctagggggaggggcatccctcagtggagggagcccggggaggattcctgggcccccacccaggca gggggctcatccactcgattaaagaggcctgcgtaagctggagagggaggacttgagttcggaccccctcgcagcctgga gtctcagtttaccgctttgtgaaatggacacaataacagtctccactctccggggaagttggcagtatttaaaagtactt aataaacgccttagcgcggtgtagaccgtgattcaagcttagcctggccgggaaacgggaggcgtggaggccgggagcag cccccggggtcatcgccctgccaccgccgcccgattgctttagcttggaaattccggagctgaagcggccagcgagggag gatgaccctctcggcccgggcaccctgtcagtccggaaataactgcagcatttgttccggaggggaaggcgcgaggtttc cgggaaagcagcaccgccccttggcccccaggtggctagcgctataaaggatcacgcgccccagtcgacgctgagctcct ctgctactcagagttgcaacctcagcctcgctatggctcccagcagcccccggcccgcgctgcccgcactcctggtcctg ctcggggctctgttcccaggtgagtcggggtggggattgccgtcgggccagttctccgaagcccgggaggaccggctccc gggtcaggtcatgcatgcttaggtagctgtttatgggaaggaggggctagagacagcgattgaaagcaacagccagtagg ttcgaatccagaccctgcatacctccacgtgtggccttgggctatagattgcagctttaaaaaagggtagggggttggag atggaggggaggggcgggcctcgttttgttgcccaggccggtcttgaactccgggggtctagccttacctcctgcctcag cctcccgagtagctgggatgaggtgtgaaccacgccttgcttggctagattgcgtctcttacagtttctcagctgtaaaa cgggaaacgttatagcggccacctggcagggtatcttggcccagcgcagcacctggccccaggactcgatcatgatggtt tgggaacttggctctgtgccaacccaacaaggcttaagggacccccacccccctcaagatgtatattctgttcctcatcc tctctgcccctggggaagtccagggctgcttctacttggggg (SEQ ID NO: 11936) gcgccccagtcgacgctgagctcctctgctactcagagttgcaacctcagcctcgctatggctcccagcagcccccggcc cgcgctgcccgcactcctggtcctgctcggggctctgttcccaggacctggcaatgcccagacatctgtgtccccctcaa aagtcatcctgccccggggaggctccgtgctggtgacatgcagcacctcctgtgaccagcccaagttgttgggcatagag accccgttgcctaaaaaggagttgctcctgcctgggaacaaccggaaggtgtatgaactgagcaatgtgcaagaagatag ccaaccaatgtgctattcaaactgccctgatgggcagtcaacagctaaaaccttcctcaccgtgtactggactccagaac gggtggaactggcacccctcccctcttggcagccagtgggcaagaaccttaccctacgctgccaggtggagggtggggca ccccgggccaacctcaccgtggtgctgctccgtggggagaaggagctgaaacgggagccagctgtgggggagcccgctga ggtcacgaccacggtgctggtgaggagagatcaccatggagccaatttctcgtgccgcactgaactggacctgcggcccc aagggctggagctgtttgagaacacctcggccccctaccagctccagacctttgtcctgccagcgactcccccacaactt gtcagcccccgggtcctagaggtggacacgcaggggaccgtggtctgttccctggacgggctgttcccagtctcggaggc ccaggtccacctggcactgggggaccagaggttgaaccccacagtcacctatggcaacgactccttctcggccaaggcct cagtcagtgtgaccgcagaggacgagggcacccagcggctgacgtgtgcagtaatactggggaaccagagccaggagaca ctgcagacagtgaccatctacagctttccggcgcccaacgtgattctgacgaagccagaggtctcagaagggaccgaggt gacagtgaagtgtgaggcccaccctagagccaaggtgacgctgaatggggttccagcccagccactgggcccgagggccc agctcctgctgaaggccaccccagaggacaacgggcgcagcttctcctgctctgcaaccctggaggtggccggccagctt atacacaagaaccagacccgggagcttcgtgtcctgtatggcccccgactggacgagagggattgtccgggaaactggac gtggccagaaaattcccagcagactccaatgtgccaggcttgggggaacccattgcccgagctcaagtgtctaaaggatg gcactttcccactgcccatcggggaatcagtgactgtcactcgagatcttgagggcacctacctctgtcgggccaggagc actcaaggggaggtcacccgcgaggtgaccgtgaatgtgctctccccccggtatgagattgtcatcatcactgtggtagc agccgcagtcataatgggcactgcaggcctcagcacgtacctctataaccgccagcggaagatcaagaaatacagactac aacaggcccaaaaagggacccccatgaaaccgaacacacaagccacgcctccctgaacctatcccgggacagggcctctt cctcggccttcccatattggtggcagtggtgccacactgaacagagtggaagacatatgccatgcagctacacctaccgg ccctgggacgccggaggacagggcattgtcctcagtcagatacaacagcatttggggccatggtacctgcacacctaaaa cactaggccacgcatctgatctgtagtcacatgactaagccaagaggaaggagcaagactcaagacatgattgatggatg ttaaagtctagcctgatgagaggggaagtggtgggggagacatagccccaccatgaggacatacaactgggaaatactga aacttgctgcctattgggtatgctgaggcccacagacttacagaagaagtggccctccatagacatgtgtagcatcaaaa cacaaaggcccacacttcctgacggatgccagcttgggcactgctgtctactgaccccaacccttgatgatatgtattta ttcatttgttattttaccagctatttattgagtgtcttttatgtaggctaaatgaacataggtctctggcctcacggagc tcccagtccatgtcacattcaaggtcaccaggtacagttgtacaggttgtacactgcaggagagtgcctggcaaaaagat caaatggggctgggacttctcattggccaacctgcctttccccagaaggagtgatttttctatcggcacaaaagcactat atggactggtaatggttcacaggttcagagattacccagtgaggccttattcctcccttccccccaaaactgacaccttt gttagccacctccccacccacatacatttctgccagtgttcacaatgacactcagcggtcatgtctggacatgagtgccc agggaatatgcccaagctatgccttgtcctcttgtcctgtttgcatttcactgggagcttgcactattgcagctccagtt tcctgcagtgatcagggtcctgcaagcagtggggaagggggccaaggtattggaggactccctcccagctttggaagggt catccgcgtgtgtgtgtgtgtgtatgtgtagacaagctctcgctctgtcacccaggctggagtgcagtggtgcaatcatg gttcactgcagtcttgaccttttgggctcaagtgatcctcccacctcagcctcctgagtagctgggaccataggctcaca acaccacacctggcaaatttgattttttttttttttttcagagacggggtctcgcaacattgcccagacttcctttgtgt tagttaataaagctttctcaactgcc (SEQ ID NO: 11937) gctataaggatcacgcgccccagtcgacgctgagctcctctgctactcagagttgcaacctcagcctcgctatggctccc agcagcccccggcccgcgctgcccgcactcctggtcctgctcggggctctgttcccaggacctggcaatgcccagacatc tgtgtccccctcaaaagtcatcctgccccggggaggctccgtgctggtgacatgcagcacctcctgtgaccagcccaagt tgttgggcatagagaccccgttgcctaaaaaggagttgctcctgcctgggaacaaccggaaggtgtatgaactgagcaat gtgcaagaagatagccaaccaatgtgctattcaaactgccctgatgggcagtcaacagctaaaaccttcctcaccgtgta ctggactccagaacgggtggaactggcacccctcccctcttggcagccagtgggcaagaaccttaccctacgctgccagg tggagggtggggcaccccgggccaacctcaccgtggtgctgctccgtggggagaaggagctgaaacgggagccagctgtg ggggagcccgctgaggtcacgaccacggtgctggtgaggagagatcaccatggagccaatttctcgtgccgcactgaact ggacctgcggccccaagggctggagctgtttgagaacacctcggccccctaccagctccagacctttgtcctgccagcga ctcccccacaacttgtcagcccccgggtcctagaggtggacacgcaggggaccgtggtctgttccctggacgggctgttc ccagtctcggaggcccaggtccacctggcactgggggaccagaggttgaaccccacagtcacctatggcaacgactcctt ctcggccaaggcctcagtcagtgtgaccgcagaggacgagggcacccagcggctgacgtgtgcagtaatactggggaacc agagccaggagacactgcagacagtgaccatctacagctttccggcgcccaacgtgattctgacgaagccagaggtctca gaagggaccgaggtgacagtgaagtgtgaggcccaccctagagccaaggtgacgctgaatggggttccagcccagccact gggcccgagggcccagctcctgctgaaggccaccccagaggacaacgggcgcagcttctcctgctctgcaaccctggagg tggccggccagcttatacacaagaaccagacccgggagcttcgtgtcctgtatggcccccgactggacgagagggattgt ccgggaaactggacgtggccagaaaattcccagcagactccaatgtgccaggcttgggggaacccattgcccgagctcaa gtgtctaaaggatggcactttcccactgcccatcggggaatcagtgactgtcactcgagatcttgagggcacctacctct gtcgggccaggagcactcaaggggaggtcacccgcaaggtgaccgtgaatgtgctctccccccggtatgagattgtcatc atcactgtggtagcagccgcagtcataatgggcactgcaggcctcagcacgtacctctataaccgccagcggaagatcaa gaaatacagactacaacaggcccaaaaagggacccccatgaaaccgaacacacaagccacgcctccctgaacctatcccg ggacagggcctcttcctcggccttcccatattggtggcagtggtgccacactgaacagagtggaagacatatgccatgca gctacacctaccggccctgggacgccggaggacagggcattgtcctcagtcagatacaacagcatttggggccatggtac ctgcacacctaaaacactaggccacgcatctgatctgtagtcacatgactaagccaagaggaaggagcaagactcaagac atgattgatggatgttaaagtctagcctgatgagaggggaagtggtgggggagacatagccccaccatgaggacatacaa ctgggaaatactgaaacttgctgcctattgggtatgctgaggccccacagacttacagaagaagtggccctccatagaca tgtgtagcatcaaaacacaaaggcccacacttcctgacggatgccagcttgggcactgctgtctactgaccccaaccctt gatgatatgtatttattcatttgttattttaccagctatttattgagtgtcttttatgtaggctaaatgaacataggtct ctggcctcacggagctcccagtccatgtcacattcaaggtcaccaggtacagttgtacaggttgtacactgcaggagagt gcctggcaaaaagatcaaatggggctgggacttctcattggccaacctgcctttccccagaaggagtgatttttctatcg gcacaaaagcactatatggactggtaatggttcacaggttcagagattacccagtgaggccttattcctcccttcccccc aaaactgacacctttgttagccacctccccacccacatacatttctgccagtgttcacaatgacactcagcggtcatgtc tggacatgagtgcccagggaatatgcccaagctatgccttgtcctcttgtcctgtttgcatttcactgggagcttgcact attgcagctccagtttcctgcagtgatcagggtcctgcaagcagtggggaagggggccaaggtattggaggactccctcc cagctttggaagcctcatccgcgtgtgtgtgtgtgtgtgtatgtgtagacaagctctcgctctgtcacccaggctggagt gcagtggtgcaatcatggttcactgcagtcttgaccttttgggctcaagtgatcctcccacctcagcctcctgagtagct gggaccataggctcacaacaccacacctggcaaatttgattttttttttttttttcagagacggggtctcgcaacattgc ccagacttcctttgtgttagttaataaagctttctcaactgcc (SEQ ID NO.-11938) ctcagcctcgctatggctcccagcagcccccggcccgcgctgcccgcactcctggtcctgctcggggctctgttcccagg acctggcaatgcccagacatctgtgtccccctcaaaagtcatcctgccccggggaggctccgtgctggtgacatgcagca cctcctgtgaccagcccaagttgttgggcatagagaccccgttgcctaaaaaggagttgctcctgcctgggaacaaccgg aaggtgtatgaactgagcaatgtgcaagaagatagccaaccaatgtgctattcaaactgccctgatgggcagtcaacagc taaaaccttcctcaccgtgtactggactccagaacgggtggaactggcacccctcccctcttggcagccagtgggcaaga accttaccctacgctgccaggtggagggtggggcaccccgggccaacctcaccgtggtgctgctccgtggggagaaggag ctgaaacgggagccagctgtgggggagcccgctgaggtcacgaccacggtgctggtgaggagagatcaccatggagccaa tttctcgtgccgcactgaactggacctgcggccccaagggctggagctgtttgagaacacctcggccccctaccagctcc agacctttgtcctgccagcgactcccccacaacttgtcagcccccgggtcctagaggtggacacgcaggggaccgtggtc tgttccctggacgggctgttcccagtctcggaggcccaggtccacctggcactgggggaccagaggttgaaccccacagt cacctatggcaacgactccttctcggccaaggcctcagtcagtgtgaccgcagaggacgagggcacccagcggctgacgt gtgcagtaatactggggaaccagagccaggagacactgcagacagtgaccatctacagctttccggcgcccaacgtgatt ctgacgaagccagaggtctcagaagggaccgaggtgacagtgaagtgtgaggcccaccctagagccaaggtgacgctgaa tggggttccagcccagccactgggcccgagggcccagctcctgctgaaggccaccccagaggacaacgggcgcagcttct cctgctctgcaaccctggaggtggccggccagcttatacacaagaaccagacccgggagcttcgtgtcctgtatggcccc cgactggacgagagggattgtccgggaaactggacgtggccagaaaattcccagcagactccaatgtgccaggcttgggg gaacccattgcccgagctcaagtgtctaaaggatggcactttcccactgcccatcggggaatcagtgactgtcactcgag atcttgagggcacctacctctgtcgggccaggagcactcaaggggaggtcacccgcgaggtgaccgtgaatgtgctctcc ccccggtatgagattgtcatcatcactgtggtagcagccgcagtcataatgggcactgcaggcctcagcacgtacctcta taaccgccagcggaagatcaagaaatacagactacaacaggcccaaaaagggacccccatgaaaccgaacacacaagcca cgcctccctgaacctatcccgggacagggcctcttcctcggccttcccatattggtggcagtggtgccacactgaacaga gtggaagacatatgccatgcagctacacctaccggccctgggacgccggaggacagggcattgtcctcagtcagatacaa cagcatttggggccatggtacctgcacacctaaaacactaggccacgcatctgatctgtagtcacatgactaagccaaga ggaagg (SEQ ID NO: 11939) aattcagaactcctcagccccccaagaaaaaaatatccccgtggaaattcctttttaatgaccgaggcgggggaaatatg cgtctctggatggccagtgactcgcagcccccttccccgataggaagggcctgcgcgtccggggacccttcgcttcccct tctgctgcgcgacctccctggcccctcggagatctccatggcgacgccgcgcgcgccccacaacaggaaagccttaggcg gcgcggcttggtgctcggagacttaagagtacccagcccctcgacgtggtggatgtcgagtcttggggtcacacgcacag gcggtggccaagcaaacacccgctcatatttagtgcatgagcctgggttcgagttgccggagcctcgcgcgtagggcagg ggttcgagcgccccttctccctgcctcgcctctgcgcctgggggctgctgcctcagtttcccagcgacaggcagggattt cgagcgtccccctcccctccctcgtcaagatccaagctagctgcctcagtttccccgcggagcctgggacgccagcggag gggctcggcgcgtagggatcacgcagcttccttcctttttctgggagctgtaaagacgcctccgccaacgccgaaagggg aagcgaggaggccgccggggtgagtgccctcgggtgtagagagaggacgccgatttccccggacgtggtgagaccgcgct tcgtcactcccacggttagcggtcgccgggaggtgcctggctctgctctggccgcttctcgagaaatgcccgtgtcagct aggtgtggacgtgacctagggggaggggcatccctcagtggagggagcccggggaggattcctgggcccccacccaggca gggggctcatccactcgattaaagaggcctgcgtaagctggagagggaggacttgagttcggaccccctcgcagcctgga gtctcagtttaccgctttgtgaaatggacacaataacagtctccactctccggggaagttggcagtatttaaaagtactt aataaacgccttagcgcggtgtagaccgtgattcaagcttagcctggccgggaaacgggaggcgtggaggccgggagcag cccccggggtcatcgccctgccaccgccgcccgattgctttagcttggaaattccggagctgaagcggccagcgagggag gatgaccctctcggcccgggcaccctgtcagtccggaaataactgcagcatttgttccggccaatgtgccaggcttgggg gaacccattgcccgagctcaagtgtctaaaggatggcactttcccactgcccatcggggaatcagtgactgtcactcgag atcttgagggcacctacctctgtcgggccaggagcactcaaggggaggtcacccgcgaggtgaccgtgaatgtgctctcc ccccggtatgagattgtcatcatcactgtggtagcagccgcagtcataatgggcactgcaggcctcagcacgtacctcta taaccgccagcggaagatcaagaaatacagactacaacaggcccaaaaagggacccccatgaaaccgaacacacaagcca cgcctccctgaacctatcccgggacagggcctcttcctcggccttcccatattggtggcagtggtgccacactgaacaga gtggaagacatatgccatgcagctacacctaccggccctgggacgccggaggacagggcattgtcctcagtcagatacaa cagcatttggggccatggtacctgcacacctaaaacactaggccacgcatctgatctgtagtcacatgactaagccaaga ggaagg (SEQ ID NO:ii940) gaattcctgccactcttcctgcaacggcccaggagctcagagctccacatctgaccttctagtcatgaccaggaccaggg cagcactcctcctgttcacagccttagcaacttctctaggtttcaacttggacacagaggagctgacagccttccgtgtg gacagcgctgggtttggagacagcgtggtccagtatgccaactcctgggtggtggttggagccccccaaaagataacagc tgccaaccaaacgggtggcctctaccagtgtggctacagcactggtgcctgtgagcccatcggcctgcaggtgcccccgg aggccgtgaacatgtccctgggcctgtccctggcgtctaccaccagcccttcccagctgctggcctgcggccccaccgtg caccacgagtgcgggaggaacatgtacctcaccggactctgcttcctcctgggccccacccagctcacccagaggctccc ggtgtccaggcaggagtgcccaagacaggagcaggacattgtgttcctgatcgatggctcaggcagcatctcctcccgca actttgccacgatgatgaacttcgtgagagctgtgataagccagttccagagacccagcacccagttttccctgatgcag ttctccaacaaattccaaacacacttcactttcgaggaattcaggcgcacgtcaaaccccctcagcctgttggcttctgt tcaccagctgcaagggtttacatacacggccaccgccatccaaaatgtcgtgcaccgattgttccatgcctcatatgggg cccgtagggatgccaccaaaattctcattgtcatcactgatgggaagaaagaaggcgacagcctggattataaggatgtc atccccatggctgatgcagcaggcatcatccgctatgcaattggggttggattagcttttcaaaacagaaattcttggaa agaattaaatgacattgcatcgaagccctcccaggaacacatatttaaagtggaggactttgatgctctgaaagatattc aaaaccaactgaaggagaagatctttgccattgagggtacggagaccacaagcagtagctccttcgaattggagatggca caggagggcttcagcgctgtgttcacacctgatggccccgttctgggggctgtggggagcttcacctggtctggaggtgc cttcctgtaccccccaaatatgagccctaccttcatcaacatgtctcaggagaatgtggacatgagggactcttacctgg gttactccaccgagctggccctctggaaaggggtgcagagcctggtcctgggggccccccgctaccagcacaccgggaag gctgtcatcttcacccaggtgtccaggcaatggaggatgaaggccgaagtcacggggactcagatcggctcctacttcgg ggcctccctctgctccgtggacgtagacaccgacggcagcaccgacctggtcctcatcggggccccccattactacgagc agacccgagggggccaggtgtctgtgtgtcccttgcccagggggtggagaaggtggtggtgtgatgctgttctctacggg gagcagggccacccctggggtcgctttggggcggctctgacagtgctgggggatgtgaatggggacaagctgacagacgt ggtcatcggggccccaggagaggaggagaaccggggtgctgtctacctgtttcacggagtcttgggacccagcatcagcc cctcccacagccagcggatcgcgggctcccagctctcctccaggctgcagtattttgggcaggcactgagcgggggtcaa gacctcacccaggatggactggtggacctggctgtgggggcccggggccaggtgctcctgctcaggaccagacctgtgct ctgggtgggggtgagcatgcagttcatacctgccgagatccccaggtctgcgtttgagtgtcgggagcaggtggtctctg agcagaccctggtacagtccaacatctgcctttacattgacaaacgttctaagaacctgcttgggagccgtgacctccaa agctctgtgaccttggacctggccctcgaccctggccgcctgagtccccgtgccaccttccaggaaacaaagaaccggag tctgagccgagtccgagtcctcgggctgaaggcacactgtgaaaacttcaacctgctgctcccgagctgcgtggaggact ctgtgacccccattaccttgcgtctgaacttcacgctggtgggcaagcccctccttgccttcagaaacctgcggcctatg ctggccgcactggctcagagatacttcacggcctccctaccctttgagaagaactgtggagccgaccatatctgccagga caatctcggcatctccttcagcttcccaggcttgaagtccctgctggtggggagtaacctggagctgaacgcagaagtga tggtgtggaatgacggggaagactcctacggaaccaccatcaccttctcccaccccgcaggactgtcctaccgctacgtg gcagagggccagaaacaagggcagctgcgttccctgcacctgacatgtgacagcgccccagttgggagccagggcacctg gagcaccagctgcagaatcaaccacctcatcttccgtggcggcgcccagatcaccttcttggctacctttgacgtctccc ccaaggctgtcctgggagaccggctgcttctgacagccaatgtgagcagtgagaacaacactcccaggaccagcaagacc accttccagctggagctcccggtgaagtatgctgtctacactgtggttagcagccacgaacaattcaccaaatacctcaa cttctcagagtctgaggagaaggaaagccatgtggccatgcacagataccaggtcaataacctgggacagagggacctgc ctgtcagcatcaacttctgggtgcctgtggagctgaaccaggaggctgtgtggatggatgtggaggtctcccacccccag aacccatcccttcggtgctcctcagagaaaatcgcacccccagcatctgacttcctggcgcacattcagaagaatcccgt gctggactgctccattgctggctgcctgcggttccgctgtgacgtcccctccttcagcgtccaggaggagctggatttca ccctgaagggcaacctcagctttggctgggtccgccagatattgcagaagaaggtgtcggtcgtgagtgtggctgaaatt acgttcgacacatccgtgtactcccagcttccaggacaggaggcatttatgagagctcagacgacaacggtgctggagaa gtacaaggtccacaaccccacccccctcatcgtaggcagctccattgggggtctgttgctgctggcactcatcacagcgg tactgtacaaagttggcttcttcaagcgtcagtacaaggaaatgatggaggaggcaaatggacaaattgccccagaaaac gggacacagacccccagcccgcccagtgagaaatgatccctctttgccttggacttcttctcccgcgattttccccactt acttaccctcacctgtcaggctgacggggaggaaccactgcaccaccgagagaggctgggatgggcctgcttcctgtctt tgggagaaaacgtcttgcttgggaaggggcctttgtcttgtcaaggttccaactggaaacccttaggacagggtccctgc tgtgttccccaaaaggacttgacttgcaatttctacctagaaatacatggacaatacccccaggcctcagtctcccttct cccatgaggcacgaatgatctttctttcctttccttttttttttttttcttttctttttttttttttttgagacggagtc tcgctctgtcacccaggctggagtgcaatggcgtgatctcggctcgctgcaacctccgcctcccgggttcaagtaattct gctgtctcagcctcctgcgtagctgggactacaggcacacgccacctcgcccggcccgatctttctaaaatacagttctg aatatgctgctcatccccacctgtcttcaacagctccccattaccctcaggacaatgtctgaactctccagcttcgcgtg agaagtccccttccatcccagagggtgggcttcagggcgcacagcatgagagcctctgtgcccccatcaccctcgtttcc agtgaattagtgtcatgtcagcatcagctcagggcttcatcgtggggctctcagttccgattccccaggctgaattggga gtgagatgcctgcatgctgggttctgcacagctggcctcccgcggttgggtcaacattgctggcctggaagggaggagcg ccctctagggagggacatggccccggtgcggctgcagctcaccagccccaggggcagaagagacccaaccacttcctatt ttttgaggctatgaatatagtacctgaaaaaatgccaagcactagattatttttttaaaaagcgtactttaaatgtttgt gttaatacacattaaaacatcgcacaaaaacgatgcatctaccgctccttgggaaataatctgaaaggtctaaaaataaa aaagccttctgtggaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa (SEQ ID NO: 11941) gaattcctgccactcttcctgcaacggcccaggagctcagagctccacatctgaccttctagtcatgaccaggaccaggg cagcactcctcctgttcacagccttagcaacttctctaggtttcaacttggacacagaggagctgacagccttccgtgtg gacagcgctgggtttggagacagcgtggtccagtatgccaactcctgggtggtggttggagccccccaaaagataacagc tgccaaccaaacgggtggcctctaccagtgtggctacagcactggtgcctgtgagcccatcggcctgcaggtgcccccgg aggccgtgaacatgtccctgggcctgtccctggcgtctaccaccagcccttcccagctgctggcctgcggccccaccgtg caccacgagtgcgggaggaacatgtacctcaccggactctgcttcctcctgggccccacccagctcacccagaggctccc ggtgtccaggcaggagtgcccaagacaggagcaggacattgtgttcctgatcgatggctcaggcagcatctcctcccgca actttgccacgatgatgaacttcgtgagagctgtgataagccagttccagagacccagcacccagttttccctgatgcag ttctccaacaaattccaaacacacttcactttcgaggaattcaggcgcacgtcaaaccccctcagcctgttggcttctgt tcaccagctgcaagggtttacatacacggccaccgccatccaaaatgtcgtgcaccgattgttccatgcctcatatgggg cccgtagggatgccaccaaaattctcattgtcatcactgatgggaagaaagaaggcgacagcctggattataaggatgtc atccccatggctgatgcagcaggcatcatccgctatgcaattggggttggattagcttttcaaaacagaaattcttggaa agaattaaatgacattgcatcgaagccctcccaggaacacat t taaagtggaggactttgatgctctgaaagatattc aaaaccaactgaaggagaagatctttgccattgagggtacggagaccacaagcagtagctccttcgaattggagatggca caggagggcttcagcgctgtgttcacacctgatggccccgttctgggggctgtggggagcttcacctggtctggaggtgc cttcctgtaccccccaaatatgagccctaccttcatcaacatgtctcaggagaatgtggacatgagggactcttacctgg gttactccaccgagctggccctctggaaaggggtgcagagcctggtcctgggggccccccgctaccagcacaccgggaag gctgtcatcttcacccaggtgtccaggcaatggaggatgaaggccgaagtcacggggactcagatcggctcctacttcgg ggcctccctctgctccgtggacgtagacaccgacggcagcaccgacctggtcctcatcggggccccccattactacgagc agacccgagggggccaggtgtctgtgtgtcccttgcccagggggtggagaaggtggtggtgtgatgctgttctctacggg gagcagggccacccctggggtcgctttggggcggctctgacagtgctgggggatgtgaatggggacaagctgacagacgt ggtcatcggggccccaggagaggaggagaaccggggtgctgtctacctgtttcacggagtcttgggacccagcatcagcc cctcccacagccagcggatcgcgggctcccagctctcctccaggctgcagtattttgggcaggcactgagcgggggtcaa gacctcacccaggatggactggtggacctggctgtgggggcccggggccaggtgctcctgctcaggaccagacctgtgct ctgggtgggggtgagcatgcagttcatacctgccgagatccccaggtctgcgtttgagtgtcgggagcaggtggtctctg agcagaccctggtacagtccaacatctgcctttacattgacaaacgttctaagaacctgcttgggagccgtgacctccaa agctctgtgaccttggacctggccctcgaccctggccgcctgagtccccgtgccaccttccaggaaacaaagaaccggag tctgagccgagtccgagtcctcgggctgaaggcacactgtgaaaacttcaacctgctgctcccgagctgcgtggaggact ctgtgacccccattaccttgcgtctgaacttcacgctggtgggcaagcccctccttgccttcagaaacctgcggcctatg ctggccgcactggctcagagatacttcacggcctccctaccctttgagaagaactgtggagccgaccatatctgccagga caatctcggcatctccttcagcttcccaggcttgaagtccctgctggtggggagtaacctggagctgaacgcagaagtga tggtgtggaatgacggggaagactcctacggaaccaccatcaccttctcccaccccgcaggactgtcctaccgctacgtg gcagagggccagaaacaagggcagctgcgttccctgcacctgacatgtgacagcgccccagttgggagccagggcacctg gagcaccagctgcagaatcaaccacctcatcttccgtggcggcgcccagatcaccttcttggctacctttgacgtctccc ccaaggctgtcctgggagaccggctgcttctgacagccaatgtgagcagtgagaacaacactcccaggaccagcaagacc accttccagctggagctcccggtgaagtatgctgtctacactgtggttagcagccacgaacaattcaccaaatacctcaa cttctcagagtctgaggagaaggaaagccatgtggccatgcacagataccaggtcaataacctgggacagagggacctgc ctgtcagcatcaacttctgggtgcctgtggagctgaaccaggaggctgtgtggatggatgtggaggtctcccacccccag aacccatcccttcggtgctcctcagagaaaatcgcacccccagcatctgacttcctggcgcacattcagaagaatcccgt gctggactgctccattgctggctgcctgcggttccgctgtgacgtcccctccttcagcgtccaggaggagctggatttca ccctgaagggcaacctcagctttggctgggtccgccagatattgcagaagaaggtgtcggtcgtgagtgtggctgaaatt acgttcgacacatccgtgtactcccagcttccaggacaggaggcatttatgagagctcagacgacaacggtgctggagaa gtacaaggtccacaaccccacccccctcatcgtaggcagctccattgggggtctgttgctgctggcactcatcacagcgg tactgtacaaagttggcttcttcaagcgtcagtacaaggaaatgatggaggaggcaaatggacaaattgccccagaaaac gggacacagacccccagcccgcccagtgagaaatgatccctctttgccttggacttcttctcccgcgattttccccactt acttaccctcacctgtcaggctgacggggaggaaccactgcaccaccgagagaggctgggatgggcctgcttcctgtctt tgggagaaaacgtcttgcttgggaaggggcctttgtcttgtcaaggttccaactggaaacccttaggacagggtccctgc tgtgttccccaaaaggacttgacttgcaatttctacctagaaatacatggacaatacccccaggcctcagtctcccttct cccatgaggcacgaatgatctttctttcctttccttttttttttttttcttttctttttttttttttttgagacggagtc tcgctctgtcacccaggctggagtgcaatggcgtgatctcggctcgctgcaacctccgcctcccgggttcaagtaattct gctgtctcagcctcctgcgtagctgggactacaggcacacgccacctcgcccggcccgatctttctaaaatacagttctg aatatgctgctcatccccacctgtcttcaacagctccccattaccctcaggacaatgtctgaactctccagcttcgcgtg agaagtccccttccatcccagagggtgggcttcagggcgcacagcatgagagcctctgtgcccccatcaccctcgtttcc agtgaattagtgtcatgtcagcatcagctcagggcttcatcgtggggctctcagttccgattccccaggctgaattggga gtgagatgcctgcatgctgggttctgcacagctggcctcccgcggttgggtcaacattgctggcctggaagggaggagcg ccctctagggagggacatggccccggtgcggctgcagctcaccagccccaggggcagaagagacccaaccacttcctatt ttttgaggctatgaatatagtacctgaaaaaatgccaagcactagattatttttttaaaaagcgtactttaaatgtttgt gttaatacacattaaaacatcgcacaaaaacgatgcatctaccgctccttgggaaataatctgaaaggtctaaaaataaa aaagccttctgtgg (SEQ ID NO: 11942) ctcgccctggtggggctgctctccctcgggtgcgtcctctctcaggagtgcacgaagttcaaggtcagcagctgccggga atgcatcgagtcggggcccggctgcacctggtgccagaagctgaacttcacagggccgggggatcctgactccattcgct gcgacacccggccacagctgctcatgaggggctgtgcggctgacgacatcatggaccccacaagcctcgctgaaacccag gaagaccacaatgggggccagaagcagctgtccccacaaaaagtgacgctttacctgcgaccaggccaggcagcagcgtt caacgtgaccttccggcgggccaagggctaccccatcgacctgtactatctgatggacctctcctactccatgcttgatg acctcaggaatgtcaagaagctaggtggcgacctgctccgggccctcaacgagatcaccgagtccggccgcattggcttc gggtccttcgtggacaagaccgtgctgccgttcgtgaacacgcaccctgataagctgcgaaacccatgccccaacaagga gaaagagtgcccgcccccgtttgccttcaggcacgtgctgaagctgaccaacaactccaaccagtttcagaccgaggtcg ggaagcagctgatttccggaaacctggatgcacccgagggtgggctggacgccatgatgcaggtcgccgcctgcccggag gaaatcggctggcgcaacgtcacgcggctgctggtgtttgccactgatgacggcttccatttcgcgggcgacggaaagct gggcgccatcctgacccccaacgacggccgctgtcacctggaggacaacttgtacaagaggagcaacgaattcgactacc catcggtgggccagctggcgcacaagctggctgaaaacaacatccagcccatcttcgcggtgaccagtaggatggtgaag acctacgagaaactcaccgagatcatccccaagtcagccgtgggggagctgtctgaggactccagcaatgtggtccatct cattaagaatgcttacaataaactctcctccagggtcttcctggatcacaacgccctccccgacaccctgaaagtcacct acgactccttctgcagcaatggagtgacgcacaggaaccagcccagaggtgactgtgatggcgtgcagatcaatgtcccg atcaccttccaggtgaaggtcacggccacagagtgcatccaggagcagtcgtttgtcatccgggcgctgggcttcacgga catagtgaccgtgcaggtccttccccagtgtgagtgccggtgccgggaccagagcagagaccgcagcctctgccatggca agggcttcttggagtgcggcatctgcaggtgtgacactggctacattgggaaaaactgtgagtgccagacacagggccgg agcagccaggagctggaaggaagctgccggaaggacaacaactccatcatctgctcagggctgggggactgtgtctgcgg gcagtgcctgtgccacaccagcgacgtccccggcaagctgatatacgggcagtactgcgagtgtgacaccatcaactgtg agcgctacaacggccaggtctgcggcggcccggggagggggctctgcttctgcgggaagtgccgctgccacccgggcttt gagggctcagcgtgccagtgcgagaggaccactgagggctgcctgaacccgcggcgtgttgagtgtagtggtcgtggccg gtgccgctgcaacgtatgcgagtgccattcaggctaccagctgcctctgtgccaggagtgccccggctgcccctcaccct gtggcaagtacatctcctgcgccgagtgcctgaagttcgaaaagggcccctttgggaagaactgcagcgcggcgtgtccg ggcctgcagctgtcgaacaaccccgtgaagggcaggacctgcaaggagagggactcagagggctgctgggtggcctacac gctggagcagcaggacgggatggaccgctacctcatctatgtggatgagagccgagagtgtgtggcaggccccaacatcg ccgccatcgtcgggggcaccgtggcaggcatcgtgctgatcggcattctcctgctggtcatctggaaggctctgatccac ctgagcgacctccgggagtacaggcgctttgagaaggagaagctcaagtcccagtggaacaatgataatccccttttcaa gagcgccaccacgacggtcatgaaccccaagtttgctgagagttaggagca (SEQ ID NO: 11943) gaattcctgccactcttcctgcaacggcccaggagctcagagctccacatctgaccttctagtcatgaccaggaccaggg cagcactcctcctgttcacagccttagcaacttctctaggtttcaacttggacacagaggagctgacagccttccgtgtg gacagcgctgggtttggagacagcgtggtccagtatgccaactcctgggtggtggttggagccccccaaaagataacagc tgccaaccaaacgggtggcctctaccagtgtggctacagcactggtgcctgtgagcccatcggcctgcaggtgcccccgg aggccgtgaacatgtccctgggcctgtccctggcgtctaccaccagcccttcccagctgctggcctgcggccccaccgtg caccacgagtgcgggaggaacatgtacctcaccggactctgcttcctcctgggccccacccagctcacccagaggctccc ggtgtccaggcaggagtgcccaagacaggagcaggacattgtgttcctgatcgatggctcaggcagcatctcctcccgca actttgccacgatgatgaacttcgtgagagctgtgataagccagttccagagacccagcacccagttttccctgatgcag ttctccaacaaattccaaacacacttcactttcgaggaattcaggcgcacgtcaaaccccctcagcctgttggcttctgt tcaccagctgcaagggtttacatacacggccaccgccatccaaaatgtcgtgcaccgattgttccatgcctcatatgggg cccgtagggatgccaccaaaattctcattgtcatcactgatgggaagaaagaaggcgacagcctggattataaggatgtc atccccatggctgatgcagcaggcatcatccgctatgcaattggggttggattagcttttcaaaacagaaattcttggaa agaattaaatgacattgcatcgaagccctcccaggaacacatatttaaagtggaggactttgatgctctgaaagatattc aaaaccaactgaaggagaagatctttgccattgagggtacggagaccacaagcagtagctccttcgaattggagatggca caggagggcttcagcgctgtgttcacacctgatggccccgttctgggggctgtggggagcttcacctggtctggaggtgc cttcctgtaccccccaaatatgagccctaccttcatcaacatgtctcaggagaatgtggacatgagggactcttacctgg gttactccaccgagctggccctctggaaaggggtgcagagcctggtcctgggggccccccgctaccagcacaccgggaag gctgtcatcttcacccaggtgtccaggcaatggaggatgaaggccgaagtcacggggactcagatcggctcctacttcgg ggcctccctctgctccgtggacgtagacaccgacggcagcaccgacctggtcctcatcggggccccccattactacgagc agacccgagggggccaggtgtctgtgtgtcccttgcccagggggtggagaaggtggtggtgtgatgctgttctctacggg gagcagggccacccctggggtcgctttggggcggctctgacagtgctgggggatgtgaatggggacaagctgacagacgt ggtcatcggggccccaggagaggaggagaaccggggtgctgtctacctgtttcacggagtcttgggacccagcatcagcc cctcccacagccagcggatcgcgggctcccagctctcctccaggctgcagtattttgggcaggcactgagcgggggtcaa gacctcacccaggatggactggtggacctggctgtgggggcccggggccaggtgctcctgctcaggaccagacctgtgct ctgggtgggggtgagcatgcagttcatacctgccgagatccccaggtctgcgtttgagtgtcgggagcaggtggtctctg agcagaccctggtacagtccaacatctgcctttacattgacaaacgttctaagaacctgcttgggagccgtgacctccaa agctctgtgaccttggacctggccctcgaccctggccgcctgagtccccgtgccaccttccaggaaacaaagaaccggag tctgagccgagtccgagtcctcgggctgaaggcacactgtgaaaacttcaacctgctgctcccgagctgcgtggaggact ctgtgacccccattaccttgcgtctgaacttcacgctggtgggcaagcccctccttgccttcagaaacctgcggcctatg ctggccgcactggctcagagatacttcacggcctccctaccctttgagaagaactgtggagccgaccatatctgccagga caatctcggcatctccttcagcttcccaggcttgaagtccctgctggtggggagtaacctggagctgaacgcagaagtga tggtgtggaatgacggggaagactcctacggaaccaccatcaccttctcccaccccgcaggactgtcctaccgctacgtg gcagagggccagaaacaagggcagctgcgttccctgcacctgacatgtgacagcgccccagttgggagccagggcacctg gagcaccagctgcagaatcaaccacctcatcttccgtggcggcgcccagatcaccttcttggctacctttgacgtctccc ccaaggctgtcctgggagaccggctgcttctgacagccaatgtgagcagtgagaacaacactcccaggaccagcaagacc accttccagctggagctcccggtgaagtatgctgtctacactgtggttagcagccacgaacaattcaccaaatacctcaa cttctcagagtctgaggagaaggaaagccatgtggccatgcacagataccaggtcaataacctgggacagagggacctgc ctgtcagcatcaacttctgggtgcctgtggagctgaaccaggaggctgtgtggatggatgtggaggtctcccacccccag aacccatcccttcggtgctcctcagagaaaatcgcacccccagcatctgacttcctggcgcacattcagaagaatcccgt gctggactgctccattgctggctgcctgcggttccgctgtgacgtcccctccttcagcgtccaggaggagctggatttca ccctgaagggcaacctcagctttggctgggtccgccagatattgcagaagaaggtgtcggtcgtgagtgtggctgaaatt acgttcgacacatccgtgtactcccagcttccaggacaggaggcatttatgagagctcagacgacaacggtgctggagaa gtacaaggtccacaaccccacccccctcatcgtaggcagctccattgggggtctgttgctgctggcactcatcacagcgg tactgtacaaagttggcttcttcaagcgtcagtacaaggaaatgatggaggaggcaaatggacaaattgccccagaaaac gggacacagacccccagcccgcccagtgagaaatgatccctctttgccttggacttcttctcccgcgattttccccactt acttaccctcacctgtcaggctgacggggaggaaccactgcaccaccgagagaggctgggatgggcctgcttcctgtctt tgggagaaaacgtcttgcttgggaaggggcctttgtcttgtcaaggttccaactggaaacccttaggacagggtccctgc tgtgttccccaaaaggacttgacttgcaatttctacctagaaatacatggacaatacccccaggcctcagtctcccttct cccatgaggcacgaatgatctttctttcctttccttttttttttttttcttttctttttttttttttttgagacggagtc tcgctctgtcacccaggctggagtgcaatggcgtgatctcggctcgctgcaacctccgcctcccgggttcaagtaat ct gctgtctcagcctcctgcgtagctgggactacaggcacacgccacctcgcccggcccgatctttctaaaatacagttctg aatatgctgctcatccccacctgtcttcaacagctccccattaccctcaggacaatgtctgaactctccagcttcgcgtg agaagtccccttccatcccagagggtgggcttcagggcgcacagcatgagagcctctgtgcccccatcaccctcgtttcc agtgaattagtgtcatgtcagcatcagctcagggcttcatcgtggggctctcagttccgattccccaggctgaattggga gtgagatgcctgcatgctgggttctgcacagctggcctcccgcggttgggtcaacattgctggcctggaagggaggagcg ccctctagggagggacatggccccggtgcggctgcagctcaccagccccaggggcagaagagacccaaccacttcctatt ttttgaggctatgaatatagtacctgaaaaaatgccaagcactagattatttttttaaaaagcgtactttaaatgtttgt gttaatacacattaaaacatcgcacaaaaacgatgcatctaccgctccttgggaaataatctgaaaggtctaaaaataaa aaagccttctgtggaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaagaattcctgccactct tcctgcaacggcccaggagctcagagctccacatctgaccttctagtcatgaccaggaccagggcagcactcctcctgtt cacagccttagcaacttctctaggtttcaacttggacacagaggagctgacagccttccgtgtggacagcgctgggtttg gagacagcgtggtccagtatgccaactcctgggtggtggttggagccccccaaaagataacagctgccaaccaaacgggt ggcctctaccagtgtggctacagcactggtgcctgtgagcccatcggcctgcaggtgcccccggaggccgtgaacatgtc cctgggcctgtccctggcgtctaccaccagcccttcccagctgctggcctgcggccccaccgtgcaccacgagtgcggga ggaacatgtacctcaccggactctgcttcctcctgggccccacccagctcacccagaggctcccggtgtccaggcaggag tgcccaagacaggagcaggacattgtgttcctgatcgatggctcaggcagcatctcctcccgcaactttgccacgatgat gaacttcgtgagagctgtgataagccagttccagagacccagcacccagttttccctgatgcagttctccaacaaattcc aaacacacttcactttcgaggaattcaggcgcacgtcaaaccccctcagcctgttggcttctgttcaccagctgcaaggg tttacatacacggccaccgccatccaaaatgtcgtgcaccgattgttccatgcctcatatggggcccgtagggatgccac caaaattctcattgtcatcactgatgggaagaaagaaggcgacagcctggattataaggatgtcatccccatggctgatg cagcaggcatcatccgctatgcaattggggttggattagcttttcaaaacagaaattcttggaaagaattaaatgacatt gcatcgaagccctcccaggaacacatatttaaagtggaggactttgatgctctgaaagatattcaaaaccaactgaagga gaagatctttgccattgagggtacggagaccacaagcagtagctccttcgaattggagatggcacaggagggcttcagcg ctgtgttcacacctgatggccccgttctgggggctgtggggagcttcacctggtctggaggtgccttcctgtacccccca aatatgagccctaccttcatcaacatgtctcaggagaatgtggacatgagggactcttacctgggttactccaccgagct ggccctctggaaaggggtgcagagcctggtcctgggggccccccgctaccagcacaccgggaaggctgtcatcttcaccc aggtgtccaggcaatggaggatgaaggccgaagtcacggggactcagatcggctcctacttcggggcctccctctgctcc gtggacgtagacaccgacggcagcaccgacctggtcctcatcggggccccccattactacgagcagacccgagggggcca ggtgtctgtgtgtcccttgcccagggggtggagaaggtggtggtgtgatgctgttctctacggggagcagggccacccct ggggtcgctttggggcggctctgacagtgctgggggatgtgaatggggacaagctgacagacgtggtcatcggggcccca ggagaggaggagaaccggggtgctgtctacctgtttcacggagtcttgggacccagcatcagcccctcccacagccagcg gatcgcgggctcccagctctcctccaggctgcagtattttgggcaggcactgagcgggggtcaagacctcacccaggatg gactggtggacctggctgtgggggcccggggccaggtgctcctgctcaggaccagacctgtgctctgggtgggggtgagc atgcagttcatacctgccgagatccccaggtctgcgtttgagtgtcgggagcaggtggtctctgagcagaccctggtaca gtccaacatctgcctttacattgacaaacgttctaagaacctgcttgggagccgtgacctccaaagctctgtgaccttgg acctggccctcgaccctggccgcctgagtccccgtgccaccttccaggaaacaaagaaccggagtctgagccgagtccga gtcctcgggctgaaggcacactgtgaaaacttcaacctgctgctcccgagctgcgtggaggactctgtgacccccattac cttgcgtctgaacttcacgctggtgggcaagcccctccttgccttcagaaacctgcggcctatgctggccgcactggctc agagatacttcacggcctccctaccctttgagaagaactgtggagccgacca atctgccaggacaatctcggcatctcc ttcagcttcccaggcttgaagtccctgctggtggggagtaacctggagctgaacgcagaagtgatggtgtggaatgacgg ggaagactcctacggaaccaccatcaccttctcccaccccgcaggactgtcctaccgctacgtggcagagggccagaaac aagggcagctgcgttccctgcacctgacatgtgacagcgccccagttgggagccagggcacctggagcaccagctgcaga atcaaccacctcatcttccgtggcggcgcccagatcaccttcttggctacctttgacgtctcccccaaggctgtcctggg agaccggctgcttctgacagccaatgtgagcagtgagaacaacactcccaggaccagcaagaccaccttccagctggagc tcccggtgaagtatgctgtctacactgtggttagcagccacgaacaattcaccaaatacctcaacttctcagagtctgag gagaaggaaagccatgtggccatgcacagataccaggtcaataacctgggacagagggacctgcctgtcagcatcaactt ctgggtgcctgtggagctgaaccaggaggctgtgtggatggatgtggaggtctcccacccccagaacccatcccttcggt gctcctcagagaaaatcgcacccccagcatctgacttcctggcgcacattcagaagaatcccgtgctggactgctccatt gctggctgcctgcggttccgctgtgacgtcccctccttcagcgtccaggaggagctggatttcaccctgaagggcaacct cagctttggctgggtccgccagatattgcagaagaaggtgtcggtcgtgagtgtggctgaaattacgttcgacacatccg tgtactcccagcttccaggacaggaggcatttatgagagctcagacgacaacggtgctggagaagtacaaggtccacaac cccacccccctcatcgtaggcagctccattgggggtctgttgctgctggcactcatcacagcggtactgtacaaagttgg cttcttcaagcgtcagtacaaggaaatgatggaggaggcaaatggacaaattgccccagaaaacgggacacagaccccca gcccgcccagtgagaaatgatccctctttgccttggacttcttctcccgcgattttccccacttacttaccctcacctgt caggctgacggggaggaaccactgcaccaccgagagaggctgggatgggcctgcttcctgtctttgggagaaaacgtctt gcttgggaaggggcctttgtcttgtcaaggttccaactggaaacccttaggacagggtccctgctgtgttccccaaaagg acttgacttgcaatttctacctagaaatacatggacaatacccccaggcctcagtctcccttctcccatgaggcacgaat gatctttctttcctttccttttttttttttttcttttctttttttttttttttgagacggagtctcgctctgtcacccag gctggagtgcaatggcgtgatctcggctcgctgcaacctccgcctcccgggttcaagtaattctgctgtctcagcctcct gcgtagctgggactacaggcacacgccacctcgcccggcccgatctttctaaaatacagttctgaatatgctgctcatcc ccacctgtcttcaacagctccccattaccctcaggacaatgtctgaactctccagcttcgcgtgagaagtccccttccat cccagagggtgggcttcagggcgcacagcatgagagcctctgtgcccccatcaccctcgtttccagtgaattagtgtcat gtcagcatcagctcagggcttcatcgtggggctctcagttccgattccccaggctgaattgggagtgagatgcctgcatg ctgggttctgcacagctggcctcccgcggttgggtcaacattgctggcctggaagggaggagcgccctctagggagggac atggccccggtgcggctgcagctcaccagccccaggggcagaagagacccaaccacttcctattttttgaggctatgaat atagtacctgaaaaaatgccaagcactagattatttttttaaaaagcgtactttaaatgtttgtgttaatacacattaaa acatcgcacaaaaacgatgcatctaccgctccttgggaaataatctgaaaggtctaaaaataaaaaagccttctgtggct cgccctggtggggctgctctccctcgggtgcgtcctctctcaggagtgcacgaagttcaaggtcagcagctgccgggaat gcatcgagtcggggcccggctgcacctggtgccagaagctgaacttcacagggccgggggatcctgactccattcgctgc gacacccggccacagctgctcatgaggggctgtgcggctgacgacatcatggaccccacaagcctcgctgaaacccagga agaccacaatgggggccagaagcagctgtccccacaaaaagtgacgctttacctgcgaccaggccaggcagcagcgttca acgtgaccttccggcgggccaagggctaccccatcgacctgtactatctgatggacctctcctactccatgcttgatgac ctcaggaatgtcaagaagctaggtggcgacctgctccgggccctcaacgagatcaccgagtccggccgcattggcttcgg gtccttcgtggacaagaccgtgctgccgttcgtgaacacgcaccctgataagctgcgaaacccatgccccaacaaggaga aagagtgcccgcccccgtttgccttcaggcacgtgctgaagctgaccaacaactccaaccagtttcagaccgaggtcggg aagcagctgatttccggaaacctggatgcacccgagggtgggctggacgccatgatgcaggtcgccgcctgcccggagga aatcggctggcgcaacgtcacgcggctgctggtgtttgccactgatgacggcttccatttcgcgggcgacggaaagctgg gcgccatcctgacccccaacgacggccgctgtcacctggaggacaacttgtacaagaggagcaacgaattcgactaccca tcggtgggccagctggcgcacaagctggctgaaaacaacatccagcccatcttcgcggtgaccagtaggatggtgaagac ctacgagaaactcaccgagatcatccccaagtcagccgtgggggagctgtctgaggactccagcaatgtggtccatctca ttaagaatgcttacaataaactctcctccagggtcttcctggatcacaacgccctccccgacaccctgaaagtcacctac gactccttctgcagcaatggagtgacgcacaggaaccagcccagaggtgactgtgatggcgtgcagatcaatgtcccgat caccttccaggtgaaggtcacggccacagagtgcatccaggagcagtcgtttgtcatccgggcgctgggcttcacggaca tagtgaccgtgcaggtccttccccagtgtgagtgccggtgccgggaccagagcagagaccgcagcctctgccatggcaag ggcttcttggagtgcggcatctgcaggtgtgacactggctacattgggaaaaactgtgagtgccagacacagggccggag cagccaggagctggaaggaagctgccggaaggacaacaactccatcatctgctcagggctgggggactgtgtctgcgggc agtgcctgtgccacaccagcgacgtccccggcaagctgatatacgggcagtactgcgagtgtgacaccatcaactgtgag cgctacaacggccaggtctgcggcggcccggggagggggctctgcttctgcgggaagtgccgctgccacccgggctttga gggctcagcgtgccagtgcgagaggaccactgagggctgcctgaacccgcggcgtgttgagtgtagtggtcgtggccggt gccgctgcaacgtatgcgagtgccattcaggctaccagctgcctctgtgccaggagtgccccggctgcccctcaccctgt ggcaagtacatctcctgcgccgagtgcctgaagttcgaaaagggcccctttgggaagaactgcagcgcggcgtgtccggg cctgcagctgtcgaacaaccccgtgaagggcaggacctgcaaggagagggactcagagggctgctgggtggcctacacgc tggagcagcaggacgggatggaccgctacctcatctatgtggatgagagccgagagtgtgtggcaggccccaacatcgcc gccatcgtcgggggcaccgtggcaggcatcgtgctgatcggcattctcctgctggtcatctggaaggctctgatccacct gagcgacctccgggagtacaggcgctttgagaaggagaagctcaagtcccagtggaacaatgataatccccttttcaaga gcgccaccacgacggtcatgaaccccaagtttgctgagagttaggagca (SEQ ID NO:119₄₄) tcttcctctcctgggccgtcctctgagcagcagacggggctaagcgttccccagctcgccttcacacacagcccgtgcca ccacaccgacggtaccatgaaggacgaggtagctctactggctgctgtcaccctcctgggagtcctgctgcaagcctact tctccctgcaggtgatctcggcgcgcagggccttccgcgtgtcgccgccgctcaccaccggcccacccgagttcgagcgc gtctaccgagcccaggtgaactgcagcgagtacttcccgctgttcctcgccacgctctgggtcgccggcatcttctttca tgaaggggcggcggccctgtgcggcctggtctacctgttcgcgcgcctccgctacttccagggctacgcgcgctccgcgc agctcaggctggcaccgctgtacgcgagcgcgcgcgccctctggctgctggtggcgctggctgcgctcggcctgctcgcc cacttcctcccggccgcgctgcgcgccgcgctcctcggacggctccggacgctgctgccgtgggcctgagaccaaggccc ccgggccgacggagccgggaaagaagagccggagcctccagctgccccggggaggggcgctcgcttccgcatcctagtct ctatcattaaagttctagtgaccga (SEQ ID NO: 11945) gagctcacagagcccccagctggggcatatctggtttccgggggcaggggcgatacccagaggaggaagaagggattctg agagagcccaacaggctccgagcctcaggctggagctgagcttggggcagcaaggaaggaccaggtgcgagggcagaacc atgcggcccgacccctgcagcacggcctgtggcctcccccagctcctgcccgtgcttctgggtcagtctggactttgcca cttctgaccaaaagccaccgcaaacccactcaagccaaaagaggaagtgaccgttaggcccaactgggaaggctggcggc caggggcactccaggcagggcgaggggggcggccgggggcgctccaggcggggcgagggagacacccagaactccaggca ggagtcctcgggtgccacctttcctctccacctggccctgcgtgggctctgtcctcagggtggcccgccgtagtccccct ccccactctgagtttcctgtcccaaagtcctaaggaagtttccagaactacatctcaccatcttgagtcagccttggctc agtgtccatctcacaggcctggaaggggcaggagtcagcactgtccagaccacagggcctgagtgtggggagggcagccg tctaggaaggtggtggagggttgttaccttgaggcaagagggctgcggggcagaaagacacagcaggtgactgttgtggg aggcccaagagaggcctgggagagggatggcccacaagggctgaccctcccgccacccagggggccttggacaggtttcc tcctggcagggtggcccttgtgcatggaacccctacaacgactaaggctggcaggcatgaggtttcctgaaggagaaaga gcttgtggggcccagtgtggctgggggggcgctgggactccattctgaagccaaaggcactgggaagggcttccgcagag gagggtttggcaggggttgccaggaacagcctggatggggacagggaacagataaggtgggtggaggagttagccgggag cctggggctggctccagcatgatgtgggggtctgcaaggccctggagaaagtggggtggtgcagcagggggcacacccac agctggagctgacccagatggacagcttgggctctgccacgcgggactaggcaaggaaggggcacgaacaagcaggaagt ggtgaggcggtctccagctagctgctctcccctgcccagactttggtttcctccctgctggcttggcctggctccctggc tctgtgtggtatggtcacacccccgtgcaccccctccactgagatggggcggggagagcaccgaggctgctcttcctctc ctgggccgtcctctgagcagcagacggggctaagcgttccccagctcgccttcacacacagcccgtgccaccacaccgac ggtaccatgaaggacgaggtagctctactggctgctgtcaccctcctgggagtcctgctgcaaggtgggctggttcctat ctaggaagagggtgggccttagatccctacagcttgccctctgccccctaggcccaggtggagggcagaggtggggactc cagcccaggcccaagctggaagagggtggggactttcagggaactggggggcacctggctgtgagagctgtaggacttgg gggtggcaagggtgccaggacaaatggtaggatagccatgggcttggggaagctgatctctgctctttccagctgtcccc tctctgggcgtcccagcaagcggcccccattccctggctctgcttcaaaggcacctccatactgggaccacgtggagcag ggtagaggtgggactccttcctccagccccctaaaaagagcctgcttaatgcctttctcagactggccctaaaggacaca ttccttggccagatatccttgccacctaagagacaccactactccacagtgtgtgggctaggataaggcacagcctgggg agggggctctgaaggggctgaacagacaggccagcctgacctccagctgctcctgcactgagctggatggccaccctgtg acacccatctgcagagggcccagaaccaaaggtgccagggctgcaggactcagggggagatggtccgacgggaggtctgg ggagggagcgcacagccagcactggtctgtgtgtggtctggcctggcctcacctgaccaagagaagggctcctgcccaca gagaaactttagggccagcccaccctctgcaactaccccagccctggggtcctggggttaggctaggagagtcccagctg caacctcctgggagcaggagagaaggtgtctgtcagatttaggcctgggaccggaatgcaggaacagagaaactgaggtt tggaggcacagggacgcaggctttagtgatcccggcctgaggcagggtcagagggccctgctggtgggcgctggtaggtg ggtgaccagggactgttagctacagggagtgtgcttccttgcacctgggaggatgcagccagctctgccctcagactccc gaggcacttcctggccagggacctgaaagctgcatttgcctgtgttttgagagtgaaatgattcagaaacaaggactcaa gtggtctctctcgcggagcaggtgtccctgtgcctgaatcactcaccctcccccatacactcacaggttgggacagggcc tc ctgcgccccaggcttcagccctgccctcctcgctgaatgtcagggacacagggcaggccagggatgggtgagacgag aggtctcctcgggcggggagggggcggggttccgccttagggaggagaggacacggccaagtgaagggccagattgcagg atccctcccactcccatctctggggcttcgggtgtccagacctgactcccgctccccctcctcccccagcctacttctcc ctgcaggtgatctcggcgcgcagggccttccgcgtgtcgccgccgctcaccaccggcccacccgagttcgagcgcgtcta ccgagcccagtgaggcgcggcgggagggcgcggggcggggagcgagccccaggcgggtccgggtcgcaggaccatcccgg ccggcgcgctcatcccacccgcccaccgcagggtgaactgcagcgagtacttcccgctgttcctcgccacgctctgggtc gccggcatcttctttcatgaaggtcggggtgtggggcaggggcgcacgcgctggacccccgggacccgcgcagggcgctc accaggcccgtgcgtacctctcgcaggggcggcggccctgtgcggcctggtctacctgttcgcgcgcctccgctacttcc agggctacgcgcgctccgcgcagctcaggtgagggccgggcggggagcggggcggggccggggaaagatcgcgggcgggc ggggctcctggggagcgggaccgaagctgggggcgggcgacgggccggagcccagcgcctttggggattcggtgggcgag ccctggcggcggccagaggaagtccccgtggggccagggttgcggcggggaagaagcgggcctcctcgcgccacctcccc gctgaccgccgcccgcaggctggcaccgctgtacgcgagcgcgcgcgccctctggctgctggtggcgctggctgcgctcg gcctgctcgcccacttcctcccggccgcgctgcgcgccgcgctcctcggacggctccggacgctgctgccgtgggcctga gaccaaggcccccgggccgacggagccgggaaagaagagccggagcctccagctgccccggggaggggcgctcgcttccg catcctagtctctatcattaaagttctagtgaccgagacccgggctgcgttctctgggtccgcgggggtggcgcaccgcg ggctacggagcctggaggggcccagcccgagtccgggcagcccggggcgggcttcctagtggcggcgtgagagtggctgc gaaggaacgagccctccccctggggcgggactggatccggtcttcacctcctaccccactccctactcagcctcggggtc acaaggccgcccagtcctgccggggttcaccctcctagcgctcagcggtctcctcaccggtccccctcctcaggggcctt ccctcgactctcagccgccgcagtccctcgtcccctggccttcacagctgacactagatagagcctgtggctctctcccc aggtgagggcaggggtttttcttttggtcagcactggatccccctcgttaactgtaggtgttcagggcagccctccgagg tccgcagagctgcgggcaccatgggaacgaagtgagtcagtgacaggcggtctcaaggaaatgtccagaagccttgggga tccaggggaggcccacagaaacaaagaagtgacttttagccaagtatgcaggagaaacggaggag (SEQ ID NO: 11946) tcttcctctcctgggccgtcctctgagcagcagacggggctaagcgttccccagctcgccttcacacacagcccgtgcca ccacaccgacggtaccatgaaggacgaggtagctctactggctgctgtcaccctcctgggagtcctgctgcaagcctact tctccctgcaggtgatctcggcgcgcagggccttccgcgtgtcgccgccgctcaccaccggcccacccgagttcgagcgc gtctaccgagcccaggtgaactgcagcgagtacttcccgctgttcctcgccacgctctgggtcgccggcatcttctttca tgaaggggcggcggccctgtgcggcctggtctacctgttcgcgcgcctccgctacttccagggctacgcgcgctccgcgc agctcaggctggcaccgctgtacgcgagcgcgcgcgccctctggctgctggtggcgctggctgcgctcggcctgctcgcc cacttcctcccggccgcgctgcgcgccgcgctcctcggacggctccggacgctgctgccgtgggcctgagaccaaggccc ccgggccgacggagccgggaaagaagagccggagcctccagctgccccggggaggggcgctcgcttccgcatcctagtct ctatcattaaagttctagtgaccgagagctcacagagcccccagctggggcatatctggtttccgggggcaggggcgata cccagaggaggaagaagggattctgagagagcccaacaggctccgagcctcaggctggagctgagcttggggcagcaagg aaggaccaggtgcgagggcagaaccatgcggcccgacccctgcagcacggcctgtggcctcccccagctcctgcccgtgc ttctgggtcagtctggactttgccacttctgaccaaaagccaccgcaaacccactcaagccaaaagaggaagtgaccgtt aggcccaactgggaaggctggcggccaggggcactccaggcagggcgaggggggcggccgggggcgctccaggcggggcg agggagacacccagaactccaggcaggagtcctcgggtgccacctttcctctccacctggccctgcgtgggctctgtcct cagggtggcccgccgtagtccccctccccactctgagtttcctgtcccaaagtcctaaggaagtttccagaactacatct caccatcttgagtcagccttggctcagtgtccatctcacaggcctggaaggggcaggagtcagcactgtccagaccacag ggcctgagtgtggggagggcagccgtctaggaaggtggtggagggttgttaccttgaggcaagagggctgcggggcagaa agacacagcaggtgactgttgtgggaggcccaagagaggcctgggagagggatggcccacaagggctgaccctcccgcca cccagggggccttggacaggtttcctcctggcagggtggcccttgtgcatggaacccctacaacgactaaggctggcagg catgaggtttcctgaaggagaaagagcttgtggggcccagtgtggctgggggggcgctgggactccattctgaagccaaa ggcactgggaagggcttccgcagaggagggtttggcaggggttgccaggaacagcctggatggggacagggaacagataa ggtgggtggaggagttagccgggagcctggggctggctccagcatgatgtgggggtctgcaaggccctggagaaagtggg gtggtgcagcagggggcacacccacagctggagctgacccagatggacagcttgggctctgccacgcgggactaggcaag gaaggggcacgaacaagcaggaagtggtgaggcggtctccagctagctgctctcccctgcccagactttggtttcctccc tgctggcttggcctggctccctggctctgtgtggtatggtcacacccccgtgcaccccctccactgagatggggcgggga gagcaccgaggctgctcttcctctcctgggccgtcctctgagcagcagacggggctaagcgttccccagctcgccttcac acacagcccgtgccaccacaccgacggtaccatgaaggacgaggtagctctactggctgctgtcaccctcctgggagtcc tgctgcaaggtgggctggttcctatctaggaagagggtgggccttagatccctacagcttgccctctgccccctaggccc aggtggagggcagaggtggggactccagcccaggcccaagctggaagagggtggggactttcagggaactggggggcacc tggctgtgagagctgtaggacttgggggtggcaagggtgccaggacaaatggtaggatagccatgggcttggggaagctg atctctgctctttccagctgtcccctctctgggcgtcccagcaagcggcccccattccctggctctgcttcaaaggcacc tccatactgggaccacgtggagcagggtagaggtgggactccttcctccagccccctaaaaagagcctgcttaatgcctt tctcagactggccctaaaggacacattccttggccagatatccttgccacctaagagacaccactactccacagtgtgtg ggctaggataaggcacagcctggggagggggctctgaaggggctgaacagacaggccagcctgacctccagctgctcctg cactgagctggatggccaccctgtgacacccatctgcagagggcccagaaccaaaggtgccagggctgcaggactcaggg ggagatggtccgacgggaggtctggggagggagcgcacagccagcactggtctgtgtgtggtctggcctggcctcacctg accaagagaagggctcctgcccacagagaaactttagggccagcccaccctctgcaactaccccagccctggggtcctgg ggttaggctaggagagtcccagctgcaacctcctgggagcaggagagaaggtgtctgtcagatttaggcctgggaccgga atgcaggaacagagaaactgaggtttggaggcacagggacgcaggctttagtgatcccggcctgaggcagggtcagaggg ccctgctggtgggcgctggtaggtgggtgaccagggactgttagctacagggagtgtgcttccttgcacctgggaggatg cagccagctctgccctcagactcccgaggcacttcctggccagggacctgaaagctgcatttgcctgtgttttgagagtg aaatgattcagaaacaaggactcaagtggtctctctcgcggagcaggtgtccctgtgcctgaatcactcaccctccccca tacactcacaggttgggacagggcctctctgcgccccaggcttcagccctgccctcctcgctgaatgtcagggacacagg gcaggccagggatgggtgagacgagaggtctcctcgggcggggagggggcggggttccgccttagggaggagaggacacg gccaagtgaagggccagattgcaggatccctcccactcccatctctggggcttcgggtgtccagacctgactcccgctcc ccctcctcccccagcctacttctccctgcaggtgatctcggcgcgcagggccttccgcgtgtcgccgccgctcaccaccg gcccacccgagttcgagcgcgtctaccgagcccagtgaggcgcggcgggagggcgcggggcggggagcgagccccaggcg ggtccgggtcgcaggaccatcccggccggcgcgctcatcccacccgcccaccgcagggtgaactgcagcgagtacttccc gctgttcctcgccacgctctgggtcgccggcatcttctttcatgaaggtcggggtgtggggcaggggcgcacgcgctgga cccccgggacccgcgcagggcgctcaccaggcccgtgcgtacctctcgcaggggcggcggccctgtgcggcctggtctac ctgttcgcgcgcctccgctacttccagggctacgcgcgctccgcgcagctcaggtgagggccgggcggggagcggggcgg ggccggggaaagatcgcgggcgggcggggctcctggggagcgggaccgaagctgggggcgggcgacgggccggagcccag cgcctttggggattcggtgggcgagccctggcggcggccagaggaagtccccgtggggccagggttgcggcggggaagaa gcgggcctcctcgcgccacctccccgctgaccgccgcccgcaggctggcaccgctgtacgcgagcgcgcgcgccctctgg ctgctggtggcgctggσtgcgctcggcctgctcgcccacttcctcccggccgcgctgcgcgccgcgctcctcggacggct ccggacgctgctgccgtgggcctgagaccaaggcccccgggccgacggagccgggaaagaagagccggagcctccagctg ccccggggaggggcgctcgcttccgcatcctagtctctatcattaaagttctagtgaccgagacccgggctgcgttctct gggtccgcgggggtggcgcaccgcgggctacggagcctggaggggcccagcccgagtccgggcagcccggggcgggcttc ctagtggcggcgtgagagtggctgcgaaggaacgagccctccccctggggcgggactggatccggtcttcacctcctacc ccactccctactcagcctcggggtcacaaggccgcccagtcctgccggggttcaccctcctagcgctcagcggtctcctc accggtccccctcctcaggggccttccctcgactctcagccgccgcagtccctcgtcccctggccttcacagctgacact agatagagcctgtggctctctccccaggtgagggcaggggtttttcttttggtcagcactggatccccctcgttaactgt aggtgttcagggcagccctccgaggtccgcagagctgcgggcaccatgggaacgaagtgagtcagtgacaggcggtctca aggaaatgtccagaagccttggggatccaggggaggcccacagaaacaaagaagtgacttttagccaagtatgcaggaga aacggaggag (SEQ ID NO: 11947) gccattctctcacatcccgtgcggtcaggaagcccttcctgaactctgacttcagttcttgctgcggtttctgcccattt ttttcatatcctctgacagctgcgaggtca ctctgctctggcttttctccaagcagaacaagtgggggctctggaaagg ttaagggacctcagtggccaccattatactttgcatctttcctgagaagtgagagttgaaagggaagcaggaaggcccat ggtcagattgaaggaaggactttttagtttcttttttttttttttgaaatggagtctcgctctgtcattcaggctggagt gcagtggtgcgatctcagctcactgcagcctccacttcctgggttcacatgattctcctgcctcagcctcccaagtagct gagactacaggcacatgccactacacccagctaacttttgtatttttagtagagacggggtttcaccatgttggccaggc tggtctcaaactgctaacatcaagtgatctgctcccctcagcctcccaaagtgctgggattaccggtatgaaccaccaca acctgccaggaatttttagtttttagcttttgcaggagacttcaaggaaaggagacattcctctgtccaggaaacgggta aggggaccatttctgcattgctggtttcccctcttggcagggtgggcatgaggcatcactgttcctgctccctcactcct gc cctcatgctcagcctgccagctcggcctcaactttgtgtgtctaaagtggaactgaatagtagctgtgagaagatag gaaagaggtagtgccaatctccttgcccagatcataaatccagactcagcagggtaaccacatgggcaagcacaaggtag gtgcttggggaaaggggaagtaattggcattctgtgtgataccaaggagaccatttggattttggcttctaccaaagaga atggagaattggttgacctaaatggaaccagtccctttaagtaaggggaggaaagggggtgctggaagatggccctcttc ccaccacctagatcatagcttgaactgaagccaaggacagagtgctgcccccttcggcatttactgatgtgccctcttta aatcatgatgttatctaacccaaacccagacccaggacctagtcacagctccaacctacacttcctattaatcttaaaac aaagcgaaacaaacacaaaaagatatcagcattgtagcctccaatctgagcccatttcccttctctggctaccatacctc cttctcctatatgataccattcactactttgttcaattatccagtctagacctgcatcttgaggccacacccagccttct cactccccacacccctctttcctctctcactgctccttcctggtctcttctcatctggccccacctctaaggagtcctcc tgccttctgggttgccctggaaaacagactatcccccctcctagtgaagggagtgggtaggggtttcagccccaccctca ggaagatgcgtcttccctgtcctctgctctgtggtacttcctctctggctgatttagcaaacagcacctagacctggggc caggcctttggcagtgggacagatccagggataggctacaccaccctgccctgaccctgggattggcatcagcttccaac cagttcctgccaaagcttgtaagtcctcccgacggccatgaacactacatcttctgcagcacccccctcactaggtgtag agttcatctctctgctggctatcatcctgctgtcagtggcgctggctgtggggcttcccggcaacagctttgtggtgtgg agtatcctgaaaaggatgcagaagcgctctgtcactgccctgatggtgctgaacctggccctggccgacctggccgtatt gctcactgctccctttttccttcacttcctggcccaaggcacctggagttttggactggctggttgccgcctgtgtcact atgtctgcggagtcagcatgtacgccagcgtcctgcttatcacggccatgagtctagaccgctcactggcggtggcccgc ccctttgtgtcccagaagctacgcaccaaggcgatggcccggcgggtgctggcaggcatctgggtgttgtcctttctgct ggccacacccgtcctcgcgtaccgcacagtagtgccctggaaaacgaacatgagcctgtgcttcccgcggtaccccagcg aagggcaccgggccttccatctaatcttcgaggctgtcacgggcttcctgctgcccttcctggctgtggtggccagctac tcggacatagggcgtcggctacaggcccggcgcttccgccgcagccgccgcaccggccgcctggtggtgctcatcatcct gaccttcgccgccttctggctgccctaccacgtggtgaacctggctgaggcgggccgcgcgctggccggccaggccgccg ggttagggctcgtggggaagcggctgagcctggcccgcaacgtgctcatcgcactcgccttcctgagcagcagcgtgaac cccgtgctgtacgcgtgcgccggcggcggcctgctgcgctcggcgggcgtgggcttcgtcgccaagctgctggagggcac gggttccgaggcgtccagcacgcgccgcgggggcagcctgggccagaccgctaggagcggccccgccgctctggagcccg gcccttccgagagcctcactgcctccagccctctcaagttaaacgaactgaactaggcctggtggaaggaggcgcacttt cctcctggcagaatgctagctctgagccagttcagtacctggaggaggagcaggggcgtggagggcgtggagggcgtggg agcgtgggaggcgggagtggagtggaagaagagggagagatggagcaaagtgagggccgagtgagagcgtgctccagcct ggctcccacaggcagctttaaccattaaaactgaagtctgaa (SEQ ID NO: 11948) aaaagaaggacctgggctttgggaagatctaaagacccaggaaggtctctgggtgggataaagccaagatgaaactcccc ctacttctggctcttctatttggggcagtttctgctcttcatctaaggtctgagacttccacctttgagacccctttggg tgctaagacgctgcctgaggatgaggagacaccagagcaggagatggaggagaccccttgcagggagctggaggaagagg aggagtggggctctggaagtgaagatgcctccaagaaagatggggctgttgagtctatctcagtgccagatatggtgcac aaaaaccttacgtgtcctgaggaagaggacacagtaaaagtggtgggcatccctgggtgccagacctgccgctacctcct ggtgagaagtcttcagacgtttagtcaagcttggtttacttgccggaggtgctacaggggcaacctggtttccatccaca acttcaatattaattatcgaatccagtgttctgtcagcgcgctcaaccagggtcaagtctggattggaggcaggatcaca ggctcgggtcgctgcagacgctttcagtgggttgacggcagccgctggaactttgcgtactgggctgctcaccagccctg gtcccgcggtggtcactgcgtggccctgtgtacccgaggaggctactggcgtcgagcccactgcctcagaagacttcctt tcatctgttcctactgagctggtcccagccagcagttcagagctgccctctcctgggcagctgcctcccctcctctgctt gccatccctccctccacctccctgcaataaaatgggttttactgaaaa (SEQ ID NO: 11949) aaaagaaggacctgggctttgggaagatctaaagacccaggaaggtctctgggtgggataaagccaagatgaaactcccc ctacttctggctcttctatttggggcagtttctgctcttcatctaaggtctgagacttccacctttgagacccctttggg tgctaagacgctgcctgaggatgaggagacaccagagcaggagatggaggagaccccttgcagggagctggaggaagagg aggagtggggctctggaagtgaagatgcctccaagaaagatggggctgttgagtctatctcagtgccagatatggtggac aaaaaccttacgtgtcctgaggaagaggacacagtaaaagtggtgggcatccctgggtgccagacctgccgctacctcct ggtgagaagtcttcagacgtttagtcaagcttggtttacttgccggaggtgctacaggggcaacctggtttccatccaca acttcaatattaattatcgaatccagtgttctgtcagcgcgctcaaccagggtcaagtctggattggaggcaggatcaca ggctcgggtcgctgcagacgctttcagtgggttgacggcagccgctggaactttgcgtactgggctgctcaccagccctg gtcccgcggtggtcactgcgtggccctgtgtacccgaggaggctactggcgtcgagcccactgcctcagaagacttcctt tcatctgttcctactgagctggtcccagccagcagttcagagctgccctctcctgggcagctgcctcccctcctctgctt gccatccctccctccacctccctgcaataaaatgggttttactgaaaa (SEQ ID NO: 11950) aaaagaaggacctgggctttgggaagatctaaagacccaggaaggtctctgggtgggataaagccaagatgaaactcccc ctacttctggctcttctatttggggcagtttctgctcttcatctaaggtctgagacttccacctttgagacccctttggg tgctaagacgctgcctgaggatgaggagacaccagagcaggagatggaggagaccccttgcagggagctggaggaagagg aggagtggggctctggaagtgaagatgcctccaagaaagatggggctgttgagtctatctcagtgccagatatggtgcac aaaaaccttacgtgtcctgaggaagaggacacagtaaaagtggtgggcatccctgggtgccagacctgccgctacctcct ggtgagaagtcttcagacgtttagtcaagcttggtttacttgccggaggtgctacaggggcaacctggtttccatccaca acttcaatattaattatcgaatccagtgttctgtcagcgcgctcaaccagggtcaagtctggattggaggcaggatcaca ggctcgggtcgctgcagacgctttcagtgggttgacggcagccgctggaactttgcgtactgggctgctcaccagccctg gtcccgcggtggtcactgcgtggccctgtgtacccgaggaggctactggcgtcgagcccactgcctcagaagacttcctt tcatctgttcctactgagctggtcccagccagcagttcagagctgccctctcctgggcagctgcctcccctcctctgctt gccatccctccctccacctccctgcaataaaatgggttttactgaaaaaaaagaaggacctgggctttgggaagatctaa agacccaggaaggtctctgggtgggataaagccaagatgaaactccccctacttctggctcttctatttggggcagtttc tgctcttcatctaaggtctgagacttccacctttgagacccctttgggtgctaagacgctgcctgaggatgaggagacac cagagcaggagatggaggagaccccttgcagggagctggaggaagaggaggagtggggctctggaagtgaagatgcctcc aagaaagatggggctgttgagtctatctcagtgccagatatggtggacaaaaaccttacgtgtcctgaggaagaggacac agtaaaagtggtgggcatccctgggtgccagacctgccgctacctcctggtgagaagtcttcagacgtttagtcaagctt ggtttacttgccggaggtgctacaggggcaacctggtttccatccacaacttcaatattaat atcgaatccagtgttct gtcagcgcgctcaaccagggtcaagtctggattggaggcaggatcacaggctcgggtcgctgcagacgctttcagtgggt tgacggcagccgctggaactttgcgtactgggctgctcaccagccctggtcccgcggtggtcactgcgtggccctgtgta cccgaggaggctactggcgtcgagcccactgcctcagaagacttcctttcatctgttcctactgagctggtcccagccag cagttcagagctgccctctcctgggcagctgcctcccctcctctgcttgccatccctccctccacctccctgcaataaaa tgggttttactgaaaa (SEQ ID NO: 11951) agcagaggggctgagaccaaaccagaaacctccaattctcatgtggaagcccatgccctcaccctccaacatgaaagcct ctgcagcacttctgtgtctgctgctcacagcagctgctttcagcccccaggggcttgctcagccagttgggattaatact tcaactacctgctgctacagatttatcaataagaaaatccctaagcagaggctggagagctacagaaggaccaccagtag ccactgtccccgggaagctgtaatcttcaagaccaaactggacaaggagatctgtgctgaccccacacagaagtgggtcc aggactttatgaagcacctggacaagaaaacccaaactccaaagctttgaacattcatgactgaactaaaaacaagccat gacttgagaaacaaataatttgtataccctgtcctttctcagagtggttctgagattattttaatctaattctaaggaat atgagctttatgtaataatgtgaatcatggtttttcttagtagattttaaaagttattaatattttaatttaatcttcca tggattttggtgggttttgaacataaagccttggatgtatatgtcatctcagtgctgtaaaaactgtgggatgctcctcc cttctctacctcatgggggtattgtataagtccttgcaagaatcagtgcaaagatttgctttaattgttaagatatgatg tccctatggaagcatattgttattatataattacatatttgcatatgtatgactcccaaattttcacataaaatagattt ttgtaaaaaa (SEQ ID NO: 11952) ggtttctattgacttgggttaatcgtgtgaccgcggtggctggcacgaaattgaccaaccctggggttagtatagc tag ttaaactttcgtttattgctaaaggttaatcactgctgtttcccgtgggggtgtggctaggctaagcgttttgagctgca ttgctgcgtgcttgatgcttgtcccttttgatcgtggtgatttagagggtgaactcactggaatggggatgcttgcatgt gtaatcttactaagagctaatagaaaggctaggaccaaaccagaaacctccaattctcatgtggaagcccatgccctcac cctccaacatgaaagcctctgcagcacttctgtgtctgctgctcacagcagctgctttcagcccccaggggcttgctcag ccagttgggattaatacttcaactacctgctgctacagatttatcaataagaaaatccctaagcagaggctggagagcta cagaaggaccaccagtagccactgtccccgggaagctgtaatcttcaagaccaaactggacaaggagatctgtgctgacc ccacacagaagtgggtccaggactttatgaagcacctggacaagaaaacccaaactccaaagctttgaacattcatgact gaactgaaaacaagccatgacttgagaaacaaataatttgtataccctgtcctttctcagagtggttctgagattatttt aatctaattctaaggaatatgagctttatgtaataatgtgaatcatggtttttcttagtagattttaaaagttattaata ttttaatttaatcttccatggattttggtgggttttgaacataaagccttggatgtatatgtcatctcagtgctgtaaaa actgtgggatgctcctcccttctctacctcatgggggtattgtataagtccttgcaagaatcagtgcaaagatttgcttt aattgttaagatatgatgtccctatggaagcatattgttat atataattacatatttgcatatgtatgactcccaaatt ttcacataaaatagatttttgtataacaaaaaaaaaaaaaaaaaa (SEQ ID NO: 11953) ggtttctattgacttgggttaatcgtgtgaccgcggtggctggcacgaaattgaccaaccctggggttagtatagcttag ttaaactttcgtttattgctaaaggttaatcactgctgtttcccgtgggggtgtggctaggctaagcgttttgagctgca ttgctgcgtgcttgatgcttgtcccttttgatcgtggtgatttagagggtgaactcactggaatggggatgcttgcatgt gtaatcttactaagagctaatagaaaggctaggaccaaaccagaaacctccaattctcatgtggaagcccatgccctcac cctccaacatgaaagcctctgcagcacttctgtgtctgctgctcacagcagctgctttcagcccccaggggcttgctcag ccagttgggattaatacttcaactacctgctgctacagatt atcaataagaaaatccctaagcagaggctggagagcta cagaaggaccaccagtagccactgtccccgggaagctgtaatcttcaagaccaaactggacaaggagatctgtgctgacc ccacacagaagtgggtccaggactttatgaagcacctggacaagaaaacccaaactccaaagctttgaacattcatgact gaactgaaaacaagccatgacttgagaaacaaataatttgtataccctgtcctttctcagagtggttctgagattatttt aatctaattctaaggaatatgagctttatgtaataatgtgaatcatggtttttcttagtagattttaaaagttattaata ttttaatttaatcttccatggattttggtgggttttgaacataaagccttggatgtatatgtcatctcagtgctgtaaaa actgtgggatgctcctcccttctctacctcatgggggtattgtataagtccttgcaagaatcagtgcaaagatttgcttt aattgttaagatatgatgtccctatggaagcatattgttattatataattacatatttgcatatgtatgactcccaaatt ttcacataaaatagatttttgtataacaaaaaaaaaaaaaaaaaa (SEQ ID NO: 11954) ggatccttaagccatcatgcaaaatatctagccatgtggagggaccactggaaagatcacacacacacacacacacacac acacacacacatacagagagagagagagacacctgagaaattccatctggtccaactgctggctgttgaagtcctcccag cccagaccccagacactgaatgaaggccttgtga atagtcaagagcaaaaaaacccagaagattgttattgttttaagt cactgttttcagatagattgctatgcagcaatagattattgaaatagacactacaattttaggtactattattctaagaa tattgaattttatttttctgctaatgttctattattttacttttctctgggttttagaaagccaccaggatttaagacag tgaagaatctttgagtcctttgtagagttgaaccaaagtttgaatgtctctttgtggactcgtgtcctagggataccact ccaaagggaaaaggggaatatcccttacatatctttgactttggtatccctgattccttcctttttctatagaatgtgtc tcatttcagagaaactggtctcttgataatagccatagattacatactgtggtcttcctctacatagaccctacctcacc taccactcctggtcttagctgaaaaacaggctagcctcgactcatactgtcatttcctatcctcccactgaagtgcactg gctcagcagatttattactccatagatttattactccattctatgattcatcctctctgcttcctataaaaggcagagac agagcttccagaggagcagaggggctgagaccaaaccagaaacctccaattctcatgtggaagcccatgccctcaccctc caacatgaaagcctctgcagcacttctgtgtctgctgctcacagcagctgctttcagcccccaggggcttgctcagccag gtaaggtccctctctccttctccttgaagcacattgccccctctctgggttatcctggaccaatcaagaagacctgatac ccacagtctcactttaacagctacttttccaagataaggtaacttagaaaaaggataaggggtgagcccaaccacacagc tgctgttgggtagagcctgaactagaattccagctgtgaaccccaaatccagctccttctaggattccagctctgggaac accctcagtgcagttaccactccagctgcttccagcagaatttgggatcagggtgatcaaagacaggaggcttctgggga tgggtgtgcgggctgtttccagataccgggagacccagaatctggtctgtggaagcccagcttccagaaacagcagctct gcagaggtggtacgtatcagggaaactcatgaccaagcattgaatgctcagagcctaaaaggggatccatagttggggta cccttgctctaaggaattggattattatattagcccctcctagcaatgcccagagtagccatcaattcctcttccgtctt tcaactggtgatggtgcatccctatttcacagtccataaaagtgaaagggagtttatgaaatgcctcaaagggcagagac attgggtttgggatgggcagcttttccctccacctcttcctttctttctgattccttcttcttaccattccctgttttac aaacagaaagacccaggacacaccctcaatggacttttcttcttgttgtttcattgcagttgggattaatacttcaacta cctgctgctacagatttatcaataagaaaatccctaagcagaggctggagagctacagaaggaccaccagtagccactgt ccccgggaagctgtaatgtatgtggacgatgaccacccacccctcacacctcagtcctaggttcttccctgggcagggaa taggactagtatcagaatgagttggagtcaaatactgtgatgcatacagcatctctaaccttatcccagacatttgccag tgagaaacaatacaagtaaagaaagtggcttctcactctcagctccctttccagctatcattttacatctcagttcgttc cttcatcctggaaccaagagagattcacttgggctaccaaaaagagctgcttctctgagtccccttcctttgttttatct tcttccttcatccctgaggcatccccatcagctaggctgatgggctagacagatttcccatagacttggtcacactccca ggctgaaccctcaaggtgttccatctgactgtctcctttctgctccacagcttcaagaccaaactggacaaggagatctg tgctgaccccacacagaagtgggtccaggactttatgaagcacctggacaagaaaacccaaactccaaagctttgaacat tcatgactgaactgaaaacaagccatgacttgagaaacaaataatttgtataccctgtcctttctcagagtggttctgag attattttaatctaattctaaggaatatgagctttatgtaataatgtgaatcatggtttttcttagtagattttaaaagt tattaatattttaatttaatcttccatggattttggtgggttttgaacataaagccttggatgtatatgtcatctcagtg ctgtaaaaactgtgggatgctcctcccttctctacctcatgggggtattgtataagtccttgcaagaatcagtgcaaaga tttgctttaattgttaagatatgatgtccctatggaagcatattgttattatataattacatatttgcatatgtatgact cccaaattttcacataaaatagatttttgtataacagctgccattcatggttttttaaaggataagtaataaagctggtg gggta (SEQ ID NO : 11955) agcagaggggctgagaccaaaccagaaacctccaattctcatgtggaagcccatgccctcaccctccaacatgaaagcct ctgcagcacttctgtgtctgctgctcacagcagctgctttcagcccccaggggcttgctcagccagttgggattaatact tcaactacctgctgctacagatttatcaataagaaaatccctaagcagaggctggagagctacagaaggaccaccagtag ccactgtccccgggaagctgtaatcttcaagaccaaactggacaaggagatctgtgctgaccccacacagaagtgggtcc aggactttatgaagcacctggacaagaaaacccaaactccaaagctttgaacattcatgactgaactaaaaacaagccat gacttgagaaacaaataatttgtataccctgtcctttctcagagtggttctgagattattttaatctaattctaaggaat atgagctttatgtaataatgtgaatcatggtttttcttagtagattttaaaagttattaatattttaatttaatcttcca tggattttggtgggttttgaacataaagccttggatgtatatgtcatctcagtgctgtaaaaactgtgggatgctcctcc cttctctacctcatgggggtattgtataagtccttgcaagaatcagtgcaaagatttgctttaattgttaagatatgatg tccctatggaagcatattgttattatataattacatatttgcatatgtatgactcccaaattttcacataaaatagattt ttgtaaaaaaggtttctattgacttgggttaatcgtgtgaccgcggtggctggcacgaaattgaccaaccctggggttag tatagcttagttaaactttcgtttattgctaaaggttaatcactgctgtttcccgtgggggtgtggctaggctaagcgtt ttgagctgcattgctgcgtgcttgatgcttgtcccttttgatcgtggtgatttagagggtgaactcactggaatggggat gcttgcatgtgtaatcttactaagagctaatagaaaggctaggaccaaaccagaaacctccaattctcatgtggaagccc atgccctcaccctccaacatgaaagcctctgcagcacttctgtgtctgctgctcacagcagctgctttcagcccccaggg gcttgctcagccagttgggattaatacttcaactacctgctgctacagatttatcaataagaaaatccctaagcagaggc tggagagctacagaaggaccaccagtagccactgtccccgggaagctgtaatcttcaagaccaaactggacaaggagatc tgtgctgaccccacacagaagtgggtccaggactttatgaagcacctggacaagaaaacccaaactccaaagctttgaac attcatgactgaactgaaaacaagccatgacttgagaaacaaataatttgtataccctgtcctttctcagagtggttctg aga tat ttaatctaattctaaggaatatgagctttatgtaataatgtgaatcatggtttttcttagtagattttaaaa gttattaatattttaatttaatcttccatggattttggtgggttttgaacataaagccttggatgtatatgtcatctcag tgctgtaaaaactgtgggatgctcctcccttctctacctcatgggggtattgtataagtccttgcaagaatcagtgcaaa gatttgctttaattgttaagatatgatgtccctatggaagcatattgttattatat attacatatttgcatatgtatga ctcccaaattttcacataaaatagatttttgtat acaaaaaaaaaaaaaaaaaaggtttctattgacttgggttaatcg tgtgaccgcggtggctggcacgaaattgaccaaccctggggttagtatagcttagttaaactttcgtttattgctaaagg ttaatcactgctgtttcccgtgggggtgtggctaggctaagcgttttgagctgcattgctgcgtgcttgatgcttgtccc ttttgatcgtggtgatttagagggtgaactcactggaatggggatgcttgcatgtgtaatcttactaagagctaatagaa aggctaggaccaaaccagaaacctccaattctcatgtggaagcccatgccctcaccctccaacatgaaagcctctgcagc acttctgtgtctgctgctcacagcagctgctttcagcccccaggggcttgctcagccagttgggattaatacttcaacta cctgctgctacagatttatcaataagaaaatccctaagcagaggctggagagctacagaaggaccaccagtagccactgt ccccgggaagctgtaatcttcaagaccaaactggacaaggagatctgtgctgaccccacacagaagtgggtccaggactt tatgaagcacctggacaagaaaacccaaactccaaagctttgaacattcatgactgaactgaaaacaagccatgacttga gaaacaaataatttgtataccctgtcctttctcagagtggttctgagattattttaatctaattctaaggaatatgagct ttatgtaataatgtgaatcatggtttttcttagtagattttaaaagttattaatattttaatttaatcttccatggattt tggtgggttttgaacataaagccttggatgtatatgtcatctcagtgctgtaaaaactgtgggatgctcctcccttctct acctcatgggggtattgtataagtccttgcaagaatcagtgcaaagatttgctttaattgttaagatatgatgtccctat ggaagcatattgttattatataattacatatttgcatatgtatgactcccaaattttcacataaaatagatttttgtata acaaaaaaaaaaaaaaaaaaggatccttaagccatcatgcaaaatatctagccatgtggagggaccactggaaagatcac acacacacacacacacacacacacacacacatacagagagagagagagacacctgagaaattccatctggtccaactgct ggctgttgaagtcctcccagcccagaccccagacactgaatgaaggccttgtgatatagtcaagagcaaaaaaacccaga agattgttattgttttaagtcactgttttcagatagattgctatgcagcaatagattattgaaatagacactacaatttt aggtactattattctaagaatattgaattttatttttctgctaatgttctattattttacttttctctgggttttagaaa gccaccaggatttaagacagtgaagaatctttgagtcctttgtagagttgaaccaaagtttgaatgtctctttgtggact cgtgtcctagggataccactccaaagggaaaaggggaatatcccttacatatctttgactttggtatccctgattccttc ctttttctatagaatgtgtctcatttcagagaaactggtctcttgataatagccatagattacatactgtggtcttcctc tacatagaccctacctcacctaccactcctggtcttagctgaaaaacaggctagcctcgactcatactgtcatttcctat cctcccactgaagtgcactggctcagcagatttattactccatagatttattactccattctatgattcatcctctctgc ttcctataaaaggcagagacagagcttccagaggagcagaggggctgagaccaaaccagaaacctccaattctcatgtgg aagcccatgccctcaccctccaacatgaaagcctctgcagcacttctgtgtctgctgctcacagcagctgctttcagccc ccaggggcttgctcagccaggtaaggtccctctctccttctccttgaagcacattgccccctctctgggttatcctggac caatcaagaagacctgatacccacagtctcactttaacagctacttttccaagataaggtaacttagaaaaaggataagg ggtgagcccaaccacacagctgctgttgggtagagcctgaactagaattccagctgtgaaccccaaatccagctccttct aggattccagctctgggaacaccctcagtgcagttaccactccagctgcttccagcagaatttgggatcagggtgatcaa agacaggaggcttctggggatgggtgtgcgggctgtttccagataccgggagacccagaatctggtctgtggaagcccag cttccagaaacagcagctctgcagaggtggtacgtatcagggaaactcatgaccaagcattgaatgctcagagcctaaaa ggggatccatagttggggtacccttgctctaaggaattggattattatattagcccctcctagcaatgcccagagtagcc atcaattcctcttccgtctttcaactggtgatggtgcatccctatttcacagtccataaaagtgaaagggagtttatgaa atgcctcaaagggcagagacattgggtttgggatgggcagcttttccctccacctcttcctttctttctgattccttctt cttaccattccctgttttacaaacagaaagacccaggacacaccctcaatggacttttcttcttgttgtttcattgcagt tgggattaatacttcaactacctgctgctacagatttatcaataagaaaatccctaagcagaggctggagagctacagaa ggaccaccagtagccactgtccccgggaagctgtaatgtatgtggacgatgaccacccacccctcacacctcagtcctag gttcttccctgggcagggaataggactagtatcagaatgagttggagtcaaatactgtgatgcatacagcatctctaacc ttatcccagacatttgccagtgagaaacaatacaagtaaagaaagtggcttctcactctcagctccctttccagctatca ttttacatctcagttcgttccttcatcctggaaccaagagagattcacttgggctaccaaaaagagctgcttctctgagt ccccttcctttgttttatcttcttccttcatccctgaggcatccccatcagctaggctgatgggctagacagatttccca tagacttggtcacactcccaggctgaaccctcaaggtgttccatctgactgtctcctttctgctccacagcttcaagacc aaactggacaaggagatctgtgctgaccccacacagaagtgggtccaggactttatgaagcacctggacaagaaaaccca aactccaaagctttgaacattcatgactgaactgaaaacaagccatgacttgagaaacaaataatttgtataccctgtcc tttctcagagtggttctgagattattttaatctaattctaaggaatatgagctttatgtaataatgtgaatcatggtttt tcttagtagattttaaaagttattaatattttaatttaatcttccatggattttggtgggttttgaacataaagccttgg atgtatatgtcatctcagtgctgtaaaaactgtgggatgctcctcccttctctacctcatgggggtattgtataagtcct tgcaagaatcagtgcaaagatttgctttaattgttaagatatgatgtccctatggaagca a tgttattatataattac atatttgcatatgtatgactcccaaattttcacataaaatagatttttgtataacagctgccattcatggttttttaaag gataagtaataaagctggtggggta (SEQ ID N0-.11956) aaccgagaggctgagactaacccagaaagatccaattctcaaactgaagctcgcactctcgcctccagcatgaaagtctc tgccgcccttctgtgcctgctgctcatagcagccaccttcattccccaagggctcgctcagccagatgcaatcaatgccc cagtcacctgctgttataacttcaccaataggaagatctcagtgcagaggctcgcgagctatagaagaatcaccagcagc aagtgtcccaaagaagctgtgatcttcaagaccattgtggccaaggagatctgtgctgaccccaagcagaagtgggttca ggattccatggaccacctggacaagcaaacccaaactccgaagacttgaacactcactccacaacccaagaatctgcagc taacttattttcccctagctttccccagacaccctgttttattttattataatgaattttgtttgttgatgtgaaacatt atgccttaagtaatgttaattcttatttaagttattgatgttttaagtttatctttcatggtactagtgttttttagata cagagacttggggaaattgcttttcctcttgaaccacagttctacccctgggatgttttgagggtctttgcaagaatcat taatacaaagaattttttttaacattccaatgcattgctaaaatattattgtggaaatgaatattttgtaactattacac caaataaatatatttttgtac (SEQ ID NO: 11957) agcccatgtcctctcttttcaggtgatgactttcccctgaggaagccctgtagcgtgcctggaggaaggggctctccaac cccagccccacctagccaccatgaacacttcagccccacctgctgtcagccccaacatcaccgtcctggcaccaggaaag ggtccctggcaagtggccttcattgggatcaccacgggcctcctgtcgctagccacagtgacaggcaacctgctggtact catctctttcaaggtcaacacggagctcaagacagtcaataactacttcctgctgagcctggcctgtgctgacctcatca tcggtaccttctccatgaacctctataccacgtacctgctcatgggccactgggctctgggcacgctggcttgtgacctc tggctggccctggactatgtggccagcaatgcctccgtcatgaatctgctgctcatcagctttgaccgctacttctccgt gactcggcccctgagctaccgtgccaagcgcacaccccgccgggcagctctgatgatcggcctggcctggctggtttcct ttgtgctctgggccccagccatcctcttctggcagtacctggtaggggagcggacgatgctagctgggcagtgctacatc cagttcctctcccagcccatcatcacctttggcacagccatggctgccttctacctccctgtcacagtcatgtgcacgct ctactggcgcatctaccgggagacagagaaccgagcacgggagctggcagcccttcagggctccgagacgccaggcaaag ggggtggcagcagcagcagctcagagaggtctcagccaggggctgagggctcaccagagactcctccaggccgctgctgt cgctgctgccgggcccccaggctgctgcaggcctacagctggaaggaagaagaggaagaggacgaaggctccatggagtc cctcacatcctcagagggagaggagcctggctccgaagtggtgatcaagatgccaatggtggaccccgaggcacaggccc ccaccaagcagcccccacggagctccccaaatacagtcaagaggccgactaagaaagggcgtgatcgagctggcaagggc cagaagccccgtggaaaggagcagctggccaagcggaagaccttctcgctggtcaaggagaagaaggcggctcggaccct gagtgccatcctcctggccttcatcctcacctggacaccgtacaacatcatggtgctggtgtccaccttctgcaaggact gtgttcccgagaccctgtgggagctgggctactggctgtgctacgtcaacagcaccatcaaccccatgtgctacgcactc tgcaacaaagccttccgggacacctttcgcctgctgctgctttgccgctgggacaagagacgctggcgcaagatccccaa gcgccctggctccgtgcaccgcactccctcccgccaatgctgatagtcccctctcctgcatccctccaccccagtccccg gg (SEQ ID NO: 11958) a tttaaaccaatgtttatattatgtttgttaattttattctatttccttgcaggtttaaatgtttatttgctacttggc tactgattagagaacgcaaaatgaataactcaacaaactcctctaacaatagcctggctcttacaagtccttataagaca tttgaagtggtgtttattgtcctggtggctggatccctcagtttggtgaccattatcgggaacatcctagtcatggtttc cattaaagtcaaccgccacctccagaccgtcaacaattactttttattcagcttggcctgtgctgaccttatcataggtg ttttctccatgaacttgtacaccctctacactgtgattggttactggcctttgggacctgtggtgtgtgacctttggcta gccctggactatgtggtcagcaatgcctcagttatgaatctgctcatcatcagctttgacaggtacttctgtgtcacaaa acctctgacctacccagtcaagcggaccacaaaaatggcaggtatgatgattgcagctgcctgggtcctctctttcatcc tctgggctccagccattctcttctggcagttcattgtaggggtgagaactgtggaggatggggagtgctacattcagttt ttttccaatgctgctgtcacctttggtacggctattgcagccttctatttgccagtgatcatcatgactgtgctatattg gcacatatcccgagccagcaagagcaggataaagaaggacaagaaggagcctgttgccaaccaagaccccgtttctccaa gtctggtacaaggaaggatagtgaagccaaacaataacaacatgcccagcagtgacgatggcctggagcacaacaaaatc 'cagaatggcaaagcccccagggatcctgtgactgaaaactgtgttcagggagaggagaaggagagctccaatgactccac ctcagtcagtgctgttgcctctaatatgagagatgatgaaataacccaggatgaaaacacagtttccacttccctgggcc attccaaagatgagaactctaagcaaacatgcatcagaattggcaccaagaccccaaaaagtgactcatgtaccccaact aataccaccgtggaggtagtggggtcttcaggtcagaatggagatgaaaagcagaatattgtagcccgcaagattgtgaa gatgactaagcagcctgcaaaaaagaagcctcctccttcccgggaaaagaaagtcaccaggacaatcttggctattctgt tggctttcatcatcacttgggccccatacaatgtcatggtgctcattaacaccttttgtgcaccttgcatccccaacact gtgtggacaattggttactggctttgttacatcaacagcactatcaaccctgcctgctatgcactttgcaatgccacctt caagaagacctttaaacaccttctcatgtgtcattataagaacataggcgctacaaggtaaaatatctttgaaaaagata gaaggtgggcaaggggagcttgagaagaataaaagggataaacgagctc (SEQ ID NO: 11959) tccagtgtacctccagatgactcccccattccctcctgtagttcatgcttttctctccccttcctccccagacacggcct acccacccctggcaaccaacatggccaacttcacacctgtcaatggcagctcgggcaatcagtccgtgcgcctggtcacg tcatcatcccacaatcgctatgagacggtggaaatggtcttcattgccacagtgacaggctccctgagcctggtgactgt cgtgggcaacatcctggtgatgctgtccatcaaggtcaacaggcagctgcagacagtcaacaactacttcctcttcagcc tggcgtgtgctgatctcatcataggcgccttctccatgaacctctacaccgtgtacatcatcaagggctactggcccctg ggcgccgtggtctgcgacctgtggctggccctggactacgtggtgagcaacgcctccgtcatgaaccttc catcatcag ctttgaccgctacttctgcgtcaccaagcctctcacctaccctgcccggcgcaccaccaagatggcaggcctcatgattg ctgctgcctgggtactgtccttcgtgctctgggcgcctgccatcttgttctggcagtttgtggtgggtaagcggacggtg cccgacaaccagtgcttcatccagttcctgtccaacccagcagtgacctttggcacagccattgctgccttctacctgcc tgtggtcatcatgacggtgctgtacatccacatctccctggccagtcgcagccgagtccacaagcaccggcccgagggcc cgaaggagaagaaagccaagacgctggccttcctcaagagcccactaatgaagcagagcgtcaagaagcccccgcccggg gaggccgcccgggaggagctgcgcaatggcaagctggaggaggcccccccgccagcgctgccaccgccaccgcgccccgt ggctgataaggacacttccaatgagtccagctcaggcagtgccacccagaacaccaaggaacgcccagccacagagctgt ccaccacagaggccaccacgcccgccatgcccgcccctcccctgcagccgcgggccctcaacccagcctccagatggtcc aagatccagattgtgacgaagcagacaggcaatgagtgtgtgacagccattgagattgtgcctgccacgccggctggcat gcgccctgcggccaacgtggcccgcaagttcgccagcatcgctcgcaaccaggtgcgcaagaagcggcagatggcggccc gggagcgcaaagtgacacgaacgatctttgccattctgctagccttcatcctcacctggacgccctacaacgtcatggtc ctggtgaacaccttctgccagagctgcatccctgacacggtgtggtccattggctactggctctgctacgtcaacagcac catcaaccctgcctgctatgctctgtgcaacgccacctttaaaaagaccttccggcacctgctgctgtgccagtatcgga acatcggcactgccaggtaggcaggcaggagtgccctaggaggtgctggtgttgcgtgcgtgtgctggggggaccacacg gct acttgctgtggggaagagttgcaggcaccattctgcgttcacgtttgctgaggaggaagttcagaagaggctctgt ggctgcattcagagaccagatct (SEQ ID NO: 11960) tcttttaacgtatgtaatgcaaagaacaaacaaataaaggcagaaatttttctaactctgtctcttctctctttccccca gactatgtcagagagtcacaatgaccttgcacaataacagtacaacctcgcctttgtttccaaacatcagctcctcctgg at cacagcccctccgatgcagggctgcccccgggaaccgtcactcatttcggcagctacaatgtttctcgagcagctgg caatttctcctctccagacggtaccaccgatgaccctctgggaggtcataccgtctggcaagtggtcttcatcgctttct taacgggcatcctggccttggtgaccatcatcggcaacatcctggtaattgtgtcatttaaggtcaacaagcagctgaag acggtcaacaactacttcctcttaagcctggcctgtgccgatctgattatcggggtcatttcaatgaatctgtttacgac ctacatcatcatgaatcgatgggccttagggaacttggcctgtgacctctggcttgccattgactacgtagccagcaatg cctctgttatgaatcttctggtcatcagctttgacagatacttttccatcacgaggccgctcacgtaccgagccaaacga acaacaaagagagccggtgtgatgatcggtctggcttgggtcatctcctttgtcctttgggctcctgccatcttgttctg gcaatactttgttggaaagagaactgtgcctccgggagagtgcttcattcagttcctcagtgagcccaccattacttttg gcacagccatcgctgctttttatatgcctgtcaccattatgactattttatactggaggatctataaggaaactgaaaag cgtaccaaagagcttgctggcctgcaagcctctgggacagaggcagagacagaaaactttgtccaccccacgggcagttc tcgaagctgcagcagttacgaacttcaacagcaaagcatgaaacgctccaacaggaggaagtatggccgctgccacttct ggttcacaaccaagagctggaaacccagctccgagcagatggaccaagaccacagcagcagtgacagttggaacaacaat gatgctgctgcctccctggagaactccgcctcctccgacgaggaggacattggctccgagacgagagccatctactccat cgtgctcaagcttccgggtcacagcaccatcctcaactccaccaagttaccctcatcggacaacctgcaggtgcctgagg aggagctggggatggtggacttggagaggaaagccgacaagctgcaggcccagaagagcgtggacgatggaggcagtttt ccaaaaagcttctccaagcttcccatccagctagagtcagccgtggacacagctaagacttctgacgtcaactcctcagt gggtaagagcacggccactctacctctgtccttcaaggaagccactctggccaagaggtttgctctgaagaccagaagtc agatcactaagcggaaaaggatgtccctggtcaaggagaagaaagcggcccagaccctcagtgcgatcttgcttgccttc atcatcacttggaccccatacaacatcatggttctggtgaacaccttttgtgacagctgcatacccaaaaccttttggaa tctgggctactggctgtgctacatcaacagcaccgtgaaccccgtgtgctatgctctgtgcaacaaaacattcagaacca ctttcaagatgctgctgctgtgccagtgtgacaaaaaaaagaggcgcaagcagcagtaccagcagagacagtcggtcatt tttcacaagcgcgcacccgagcaggccttgtagaatgaggttgtatcaatagcagtgacaaaacgacacatca (SEQ ID NO: 11961) agcccatgtcctctcttttcaggtgatgactttcccctgaggaagccctgtagcgtgcctggaggaaggggctctccaac cccagccccacctagccaccatgaacacttcagccccacctgctgtcagccccaacatcaccgtcctggcaccaggaaag ggtccctggcaagtggccttcattgggatcaccacgggcctcctgtcgctagccacagtgacaggcaacctgctggtact catctctttcaaggtcaacacggagctcaagacagtcaataactacttcctgctgagcctggcctgtgctgacctcatca tcggtaccttctccatgaacctctataccacgtacctgctcatgggccactgggctctgggcacgctggcttgtgacctc tggctggccctggactatgtggccagcaatgcctccgtcatgaatctgctgctcatcagctttgaccgctacttctccgt gactcggcccctgagctaccgtgccaagcgcacaccccgccgggcagctctgatgatcggcctggcctggctggtttcct ttgtgctctgggccccagccatcctcttctggcagtacctggtaggggagcggacgatgctagctgggcagtgctacatc cagttcctctcccagcccatcatcacctttggcacagccatggctgccttctacctccctgtcacagtcatgtgcacgct ctactggcgcatctaccgggagacagagaaccgagcacgggagctggcagcccttcagggctccgagacgccaggcaaag ggggtggcagcagcagcagctcagagaggtctcagccaggggctgagggctcaccagagactcctccaggccgctgctgt cgctgctgccgggcccccaggctgctgcaggcctacagctggaaggaagaagaggaagaggacgaaggctccatggagtc cctcacatcctcagagggagaggagcctggctccgaagtggtgatcaagatgccaatggtggaccccgaggcacaggccc ccaccaagcagcccccacggagctccccaaatacagtcaagaggccgactaagaaagggcgtgatcgagctggcaagggc cagaagccccgtggaaaggagcagctggccaagcggaagaccttctcgctggtcaaggagaagaaggcggctcggaccct gagtgccatcctcctggccttcatcctcacctggacaccgtacaacatcatggtgctggtgtccaccttctgcaaggact gtgttcccgagaccctgtgggagctgggctactggctgtgctacgtcaacagcaccatcaaccccatgtgctacgcactc tgcaacaaagccttccgggacacctttcgcctgctgctgctttgccgctgggacaagagacgctggcgcaagatccccaa gcgccctggctccgtgcaccgcactccctcccgccaatgctgatagtcccctctcctgcatccctccaccccagtccccg ggattttaaaccaatgtttatattatgtttgttaattttattctatttccttgcaggtttaaatgtttatttgctacttg gctactgattagagaacgcaaaatgaataactcaacaaactcctctaacaatagcctggctcttacaagtccttataaga catttgaagtggtgtttattgtcctggtggctggatccctcagtttggtgaccattatcgggaacatcctagtcatggtt tccattaaagtcaaccgccacctccagaccgtcaacaattactttttattcagcttggcctgtgctgaccttatcatagg tgttttctccatgaacttgtacaccctctacactgtgattggttactggcctttgggacctgtggtgtgtgacctttggc tagccctggactatgtggtcagcaatgcctcagttatgaatctgctcatcat agctttgacaggtacttctgtgtcaca aaacctctgacctacccagtcaagcggaccacaaaaatggcaggtatgatgattgcagctgcctgggtcctctctttcat cctctgggctccagccattctcttctggcagttcattgtaggggtgagaactgtggaggatggggagtgctacattcagt ttttttccaatgctgctgtcacctttggtacggctattgcagccttctatttgccagtgatcatcatgactgtgctatat tggcacatatcccgagccagcaagagcaggataaagaaggacaagaaggagcctgttgccaaccaagaccccgtttctcc aagtctggtacaaggaaggatagtgaagccaaacaataacaacatgcccagcagtgacgatggcctggagcacaacaaaa tccagaatggcaaagcccccagggatcctgtgactgaaaactgtgttcagggagaggagaaggagagctccaatgactcc acctcagtcagtgctgttgcctctaatatgagagatgatgaaataacccaggatgaaaacacagtttccacttccctggg ccattccaaagatgagaactctaagcaaacatgcatcagaattggcaccaagaccccaaaaagtgactcatgtaccccaa ctaataccaccgtggaggtagtggggtcttcaggtcagaatggagatgaaaagcagaatattgtagcccgcaagattgtg aagatgactaagcagcctgcaaaaaagaagcctcctccttcccgggaaaagaaagtcaccaggacaatcttggctattct gttggctttcatcatcacttgggccccatacaatgtcatggtgctcattaacaccttttgtgcaccttgcatccccaaca ctgtgtggacaattggttactggctttgttacatcaacagcactatcaaccctgcctgctatgcactttgcaatgccacc ttcaagaagacctttaaacaccttctcatgtgtcattataagaacataggcgctacaaggtaaaatatctttgaaaaaga tagaaggtgggcaaggggagcttgagaagaataaaagggataaacgagctctccagtgtacctccagatgactcccccat tccctcctgtagttcatgcttttctctccccttcctccccagacacggcctacccacccctggcaaccaacatggccaac ttcacacctgtcaatggcagctcgggcaatcagtccgtgcgcctggtcacgtcatcatcccacaatcgctatgagacggt ggaaatggtcttca tgccacagtgacaggctccctgagcctggtgactgtcgtgggcaacatcctggtgatgctgtcca tcaaggtcaacaggcagctgcagacagtcaacaactacttcctcttcagcctggcgtgtgctgatctcatcataggcgcc ttctccatgaacctctacaccgtgtacatcatcaagggctactggcccctgggcgccgtggtctgcgacctgtggctggc cctggactacgtggtgagcaacgcctccgtcatgaaccttctcatcatcagctttgaccgctacttctgcgtcaccaagc ctctcacctaccctgcccggcgcaccaccaagatggcaggcctcatgattgctgctgcctgggtactgtccttcgtgctc tgggcgcctgccatcttgttctggcagtttgtggtgggtaagcggacggtgcccgacaaccagtgcttcatccagttcct gtccaacccagcagtgacctttggcacagccattgctgccttctacctgcctgtggtcatcatgacggtgctgtacatcc acatctccctggccagtcgcagccgagtccacaagcaccggcccgagggcccgaaggagaagaaagccaagacgctggcc ttcctcaagagcccactaatgaagcagagcgtcaagaagcccccgcccggggaggccgcccgggaggagctgcgcaatgg caagctggaggaggcccccccgccagcgctgccaccgccaccgcgccccgtggctgataaggacacttccaatgagtcca gctcaggcagtgccacccagaacaccaaggaacgcccagccacagagctgtccaccacagaggccaccacgcccgccatg cccgcccctcccctgcagccgcgggccctcaacccagcctccagatggtccaagatccagattgtgacgaagcagacagg caatgagtgtgtgacagccattgagattgtgcctgccacgccggctggcatgcgccctgcggccaacgtggcccgcaagt tcgccagcatcgctcgcaaccaggtgcgcaagaagcggcagatggcggcccgggagcgcaaagtgacacgaacgatcttt gccattctgctagccttcatcctcacctggacgccctacaacgtcatggtcctggtgaacaccttctgccagagctgcat ccctgacacggtgtggtccattggctactggctctgctacgtcaacagcaccatcaaccctgcctgctatgctctgtgca acgccacctttaaaaagaccttccggcacctgctgctgtgccagtatcggaacatcggcactgccaggtaggcaggcagg agtgccctaggaggtgctggtgttgcgtgcgtgtgctggggggaccacacggctcacttgctgtggggaagagttgcagg caccattctgcgttcacgtttgctgaggaggaagttcagaagaggctctgtggctgcattcagagaccagatcttctttt aacgtatgtaatgcaaagaacaaacaaataaaggcagaaatttttctaactctgtctcttctctctttcccccagactat gtcagagagtcacaatgaccttgcacaataacagtacaacctcgcctttgtttccaaacatcagctcctcctggatacac agcccctccgatgcagggctgcccccgggaaccgtcactcatttcggcagctacaatgtttctcgagcagctggcaattt ctcctctccagacggtaccaccgatgaccctctgggaggtcataccgtctggcaagtggtcttcatcgctttcttaacgg gcatcctggccttggtgaccatcatcggcaacatcctggtaattgtgtcatttaaggtcaacaagcagctgaagacggtc aacaactacttcctcttaagcctggcctgtgccgatctgattatcggggtcatttcaatgaatctgtttacgacctacat catcatgaatcgatgggccttagggaacttggcctgtgacctctggcttgccattgactacgtagccagcaatgcctctg ttatgaatcttctggtcatcagctttgacagatacttttccatcacgaggccgctcacgtaccgagccaaacgaacaaca aagagagccggtgtgatgatcggtctggcttgggtcatctcctttgtcctttgggctcctgccatcttgttctggcaata ctttgttggaaagagaactgtgcctccgggagagtgcttcattcagttcctcagtgagcccaccattacttttggcacag ccatcgctgctttttatatgcctgtcaccattatgactattttatactggaggatctataaggaaactgaaaagcgtacc aaagagcttgctggcctgcaagcctctgggacagaggcagagacagaaaactttgtccaccccacgggcagttctcgaag ctgcagcagttacgaacttcaacagcaaagcatgaaacgctccaacaggaggaagtatggccgctgccacttctggttca caaccaagagctggaaacccagctccgagcagatggaccaagaccacagcagcagtgacagttggaacaacaatgatgct gctgcctccctggagaactccgcctcctccgacgaggaggacattggctccgagacgagagccatctactccatcgtgct caagcttccgggtcacagcaccatcctcaactccaccaagttaccctcatcggacaacctgcaggtgcctgaggaggagc tggggatggtggacttggagaggaaagccgacaagctgcaggcccagaagagcgtggacgatggaggcagttttccaaaa agcttctccaagcttcccatccagctagagtcagccgtggacacagctaagacttctgacgtcaactcctcagtgggtaa gagcacggccactctacctctgtccttcaaggaagccactctggccaagaggtttgctctgaagaccagaagtcagatca ctaagcggaaaaggatgtccctggtcaaggagaagaaagcggcccagaccctcagtgcgatcttgcttgccttcatcatc acttggaccccatacaacatcatggttctggtgaacaccttttgtgacagctgcatacccaaaaccttttggaatctggg ctactggctgtgctacatcaacagcaccgtgaaccccgtgtgctatgctctgtgcaacaaaacattcagaaccactttca agatgctgctgctgtgccagtgtgacaaaaaaaagaggcgcaagcagcagtaccagcagagacagtcggtcatttttcac aagcgcgcacccgagcaggccttgtagaatgaggttgtatcaatagcagtgacaaaacgacacatca (SEQ ID NO: 11962) atggataacgtcctcccggtggactcagacctctccccaaacatctccactaacacctcggaacccaatcagttcgtgca accagcctggcaaattgtcctttgggcagctgcttacacggtcattgtggtgacctctgtggtgggcaacgtggtagtga tgtggatcatcttagcccacaaaagaatgaggacagtgacgaactattttctggtgaacctggccttcgcggaggcctcc atggctgcattcaatacagtggtgaacttcacctatgctgtccacaacgaatggtactacggcctgttctactgcaagtt ccacaacttcttccccatcgccgcttgcttcgccagtatctactccatgacggctgtggcctttgataggtacatggcca tcatacatcccctccagccccggctgtcagccacagccaccaaagtggtcatctgtgtcatctgggtcctggctctcctg ctggccttcccccagggctactactcaaccacagagaccatgcccagcagagtcgtgtgcatgatcgaatggccagagca tccgaacaagatttatgagaaagtgtaccacatctgtgtgactgtgctgatctacttcctccccctgctggtgattggct atgcatacaccatagtgggaatcacactatgggccagtgagatccccggggactcctctgaccgctaccacgagcaagtc tctgccaagcgcaaggtggtcaaaatgatgattgtcgtggtgtgcaccttcgccatctgctggctgcccttccacatctt cttcctcctgccctacatcaacccagatctctacctgaagaagtttatccagcaggtctacctggccatcatgtggctgg ccatgagctccaccatgtacaaccccatcatctactgctgcctcaatgacaggttccgtctgggcttcaagcatgccttc cggtgctgccccttcatcagcgccggcgactatgaggggctggaaatgaaatccacccggtatctccagacccagggcag tgtgtacaaagtcagccgcctggagaccaccatctccacagtggtgggggcccacgaggaggagccagaggacggcccca aggccacaccctcgtccctggacctgacctccaactgctcttcacgaagtgactccaagaccatgacagagagcttcagc ttctcctccaatgtgctctcctagggatcc (SEQ ID NO: 11963) ctattgcagtatctttcagcttccagtcttatctgaagaccccggcaccaaagtgaccaggaggcagagaagaacttcag aggagtctcgtcttgggctgcccgtgggtgagtgggagggtccgggactgcagaccggtggcgatggccactctcccagc agcagaaacctggatagacgggggtggaggcgtgggtgcagacgccgtgaacctgaccgcctcgctagctgccggggcgg ccacgggggcagttgagactgggtggctgcaactgctggaccaagctggcaacctctcctcctccccttccgcgctggga ctgcctgtggcttcccccgcgccctcccagccctgggccaacctcaccaaccagttcgtgcagccgtcctggcgcatcgc gctctggtccctggcgtatggtgtggtggtggcagtggcagttttgggaaatctca cgtcatctggatcatcctggccc acaagcgcatgaggactgtcaccaactacttccttgtgaacctggctttctccgacgcctccatggccgccttcaacacg ttggtcaatttcatctacgcgcttcatagcgagtggtactttggcgccaactactgccgcttccagaacttctttcctat cacagctgtgttcgccagcatctactccatgacggccattgcggtggacaggtatatggctattattgatcccttgaaac ccagactgtctgctacagcaaccaagattgtcattggaagtatttggattctagcatttctacttgccttccctcagtgt ctttattccaaaaccaaagtcatgccaggccgtactctctgctttgtgcaatggccagaaggtcccaaacaacatttcac ttaccatattatcgtcattatactggtgtactgtttcccattgctcatcatgggtattacatacaccattgttggaatta ctctctggggaggagaaatcccaggagatacctgtgacaagtatcatgagcagctaaaggccaaaagaaaggttgtcaaa atgatgattattgttgtcatgacatttgctatctgctggctgccctatcatatttacttcattctcactgcaatctatca acaactaaatagatggaaatacatccagcaggtctacctggctagcttttggctggcaatgagctcaaccatgtacaatc ccatcatctactgctgtctgaataaaagatttcgagctggcttcaagagagcatttcgctggtgtcctttcatcaaagtt tccagctatgatgagctagagctcaagaccaccaggtt catccaaaccggcaaagcagtatgtacaccgtgaccagaat ggagtccatgacagtcgtgtttgaccccaacgatgcagacaccaccaggtccagtcggaagaaaagagcaacgccaagag acccaagtttcaatggctgctctcgcaggaattccaaatctgcctccgccacttcaagtttcataagctcaccctatacc tctgtggatgaatattcttaattccatttcctgaggtaaaagattagtgtgagaccatcatggtgccagtctaggacccc attctcctatttatcagtcctgtcctatataccctctagaaacagaaagcaatttttaggcagctatggtcaaattgaga aaggtagtgtataaatgtgacaaagacactaataacatgttagcctccacccaaaataaaatgggctttaaattt (SEQ ID NO: 11964) atggggacctgtgacattgtgactgaagccaatatctcatctggccctgagagcaacaccacgggcatcacagccttctc catgcccagctggcagctggcactgtgggcaccagcctacctggccctggtgctggtggccgtgacgggtaatgccatcg tcatctggatcatcctggcccatcggaggatgcgcacagtcaccaactacttcatcgtcaatctggcgctggctgacctc tgcatggctgccttcaatgccgccttcaactttgtctatgccagccacaacatctggtactttggccgtgccttctgcta cttccagaacctcttccccatcacagccatgtttgtcagcatctactccatgaccgccattgctgccgacaggtacatgg ccatcgtccaccccttccagcctcggctttcagctcccagcaccaaggcggttattgctggcatctggctggtggctctc gccctggcctcccctcagtgcttctactccaccgtcaccatggaccagggtgccaccaagtgcgtggtggcctggcccga agacagcgggggcaagacgctcctcctgtaccacctcgtggtgatcgccctcatctacttcctgccgctcgcggtgatgt ttgtagcctacagcgtcatcggcctcacgctctggaggcgcgcagtgcccggacatcaggcgcacggtgccaacctccgc catctgcaggccaagaagaagtttgtgaagaccatggtgctggtggtgctgacgtttgccatctgctggctgccctacca σctctacttcatcctgggcagcttccaggaggacatctactgccacaagttcatccagcaagtctacctggcactcttct ggttggccatgagctctaccatgtacaatcccatcatctactgctgtctcaaccacaggtttcgctctgggttccggctt gccttccgctgctgcccatgggtcacacccaccaaggaagataagctcgagctgactcccacgacctccctctccacgag agtcaacaggtgtcacactaaggagactttgttcatggctggggacacagccccctccgaggctaccagtggggaggcgg ggcgtccccaggatggatcagggctatggtttgggtatggtttgcttgcccccaccaaaactcatgttgaaatttga (SEQ ID NO: 11965) atggataacgtcctcccggtggactcagacctctccccaaacatctccactaacacctcggaacccaatcagttcgtgca accagcctggcaaattgtcctttgggcagctgcttacacggtcattgtggtgacctctgtggtgggcaacgtggtagtga tgtggatcatcttagcccacaaaagaatgaggacagtgacgaactattttctggtgaacctggccttcgcggaggcctcc atggctgcattcaatacagtggtgaacttcacctatgctgtccacaacgaatggtactacggcctgttctactgcaagtt ccacaacttcttccccatcgccgcttgcttcgccagtatctactccatgacggctgtggcctttgataggtacatggcca tcatacatcccctccagccccggctgtcagccacagccaccaaagtggtcatctgtgtcatctgggtcctggctctcctg ctggccttcccccagggctactactcaaccacagagaccatgcccagcagagtcgtgtgcatgatcgaatggccagagca tccgaacaagatttatgagaaagtgtaccacatctgtgtgactgtgctgatctacttcctccccctgctggtgattggct atgcatacaccatagtgggaatcacactatgggccagtgagatccccggggactcctctgaccgctaccacgagcaagtc tctgccaagcgcaaggtggtcaaaatgatgattgtcgtggtgtgcaccttcgccatctgctggctgcccttccacatctt cttcctcctgccctacatcaacccagatctctacctgaagaagtttatccagcaggtctacctggccatcatgtggctgg ccatgagctccaccatgtacaaccccatcatctactgctgcctcaatgacaggttccgtctgggcttcaagcatgccttc cggtgctgccccttcatcagcgccggcgactatgaggggctggaaatgaaatccacccggtatctccagacccagggcag tgtgtacaaagtcagccgcctggagaccaccatctccacagtggtgggggcccacgaggaggagccagaggacggcccca aggccacaccctcgtccctggacctgacctccaactgctcttcacgaagtgactccaagaccatgacagagagcttcagc ttctcctccaatgtgctctcctagggatccctattgcagtatctttcagcttccagtcttatctgaagaccccggcacca aagtgaccaggaggcagagaagaacttcagaggagtctcgtcttgggctgcccgtgggtgagtgggagggtccgggactg cagaccggtggcgatggccactctcccagcagcagaaacctggatagacgggggtggaggcgtgggtgcagacgccgtga acctgaccgcctcgctagctgccggggcggccacgggggcagttgagactgggtggctgcaactgctggaccaagctggc aacctctcctcctccccttccgcgctgggactgcctgtggcttcccccgcgccctcccagccctgggccaacctcaccaa ccagttcgtgcagccgtcctggcgcatcgcgctctggtccctggcgtatggtgtggtggtggcagtggcagttttgggaa atctcatcgtcatctggatcatcctggcccacaagcgcatgaggactgtcaccaactacttccttgtgaacctggctttc tccgacgcctccatggccgccttcaacacgttggtcaatttcatctacgcgcttcatagcgagtggtactttggcgccaa ctactgccgcttccagaacttctttcctatcacagctgtgttcgccagcatctactccatgacggccattgcggtggaca ggtatatggctattattgatcccttgaaacccagactgtctgctacagcaaccaagattgtcattggaagtatttggatt ctagcatttctacttgccttccctcagtgtctttattccaaaaccaaagtcatgccaggccgtactctctgctttgtgca atggccagaaggtcccaaacaacatttcacttaccatattatcgtcattatactggtgtactgtttcccattgctcatca tgggtattacatacaccattgttggaattactctctggggaggagaaatcccaggagatacctgtgacaagtatcatgag cagctaaaggccaaaagaaaggttgtcaaaatgatgattattgttgtcatgacatttgctatctgctggctgccctatca tatttacttcattctcactgcaatctatcaacaactaaatagatggaaatacatccagcaggtctacctggctagctttt ggctggcaatgagctcaaccatgtacaatcccatcatctactgctgtctgaataaaagatttcgagctggcttcaagaga gcatttcgctggtgtcctttcatcaaagtttccagctatgatgagctagagctcaagaccaccaggtttcatccaaaccg gcaaagcagtatgtacaccgtgaccagaatggagtccatgacagtcgtgtttgaccccaacgatgcagacaccaccaggt ccagtcggaagaaaagagcaacgccaagagacccaagtttcaatggctgctctcgcaggaattccaaatctgcctccgcc acttcaagtttcataagctcaccctatacctctgtggatgaatattcttaattccatttcctgaggtaaaagattagtgt gagaccatcatggtgccagtctaggaccccattctcctatttatcagtcctgtcctatataccctctagaaacagaaagc aatttttaggcagctatggtcaaattgagaaaggtagtgtataaatgtgacaaagacactaataacatgttagcctccac ccaaaataaaatgggctttaaatttatggggacctgtgacattgtgactgaagccaatatctcatctggccctgagagca acaccacgggcatcacagccttctccatgcccagctggcagctggcactgtgggcaccagcctacctggccctggtgctg gtggccgtgacgggtaatgccatcgtcatctggatcatcctggcccatcggaggatgcgcacagtcaccaactacttcat cgtcaatctggcgctggctgacctctgcatggctgccttcaatgccgccttcaactttgtctatgccagccacaacatct ggtactttggccgtgccttctgctacttccagaacctcttccccatcacagccatgtttgtcagcatctactccatgacc gccattgctgccgacaggtacatggccatcgtccaccccttccagcctcggctttcagctcccagcaccaaggcggttat tgctggcatctggctggtggctctcgccctggcctcccctcagtgcttctactccaccgtcaccatggaccagggtgcca ccaagtgcgtggtggcctggcccgaagacagcgggggcaagacgctcctcctgtaccacctcgtggtgatcgccctcatc tacttcctgccgctcgcggtgatgtttgtagcctacagcgtcatcggcctcacgctctggaggcgcgcagtgcccggaca tcaggcgcacggtgccaacctccgccatctgcaggccaagaagaagtttgtgaagaccatggtgctggtggtgctgacgt ttgccatctgctggctgccctaccacctctacttcatcctgggcagcttccaggaggacatctactgccacaagttcatc cagcaagtctacctggcactcttctggttggccatgagctctaccatgtacaatcccatcatctactgctgtctcaacca caggtttcgctctgggttccggcttgccttccgctgctgcccatgggtcacacccaccaaggaagataagctcgagctga ctcccacgacctccctctccacgagagtcaacaggtgtcacactaaggagactttgttcatggctggggacacagccccc tccgaggctaccagtggggaggcggggcgtccccaggatggatcagggctatggtttgggtatggtttgcttgcccccac caaaactcatgttgaaatttga (SEQ ID NO: 11966) ctccataaggcacaaactttcagagacagcagagcacacaagcttctaggacaagagccaggaagaaaccaccggaagga accatctcactgtgtgtaaacatgacttccaagctggccgtggctctcttggcagccttcctgatttctgcagctctgtg tgaaggtgcagttttgccaaggagtgctaaagaacttagatgtcagtgcataaagacatactccaaacctttccacccca aatttatcaaagaactgagagtgattgagagtggaccacactgcgccaacacagaaattattgtaaagctttctgatgga agagagctctgtctggaccccaaggaaaactgggtgcagagggttgtggagaagtttttgaagagggctgagaattcata aaaaaattcattctctgtggtatccaagaatcagtgaagatgccagtgaaacttcaagcaaatctacttcaacacttcat gtattgtgtgggtctgttgtagggttgccagatgcaatacaagattcctggttaaatttgaatttcagtaaacaatgaat agtttttcattgtaccatgaaatatccagaacatacttatatgtaaagtattatttatttgaatctacaaaaaacaacaa ataatttttaaatataaggattttcctagatattgcacgggagaatatacaaatagcaaaattgggccaagggccaagag aatatccgaactttaatttcaggaattgaatgggtttgctagaatgtgatatttgaagcatcacataaaaatgatgggac aataaattttgccataaagtcaaatttagctggaaatcctggatttttttctgttaaatctggcaaccctagtctgσtag ccaggatccacaagtccttgttccactgtgccttggtttctcctttatttctaagtggaaaaagtattagccaccatctt acctcacagtgatgttgtgaggacatgtggaagcactttaagttttttcatcataacataaattattttcaagtgtaact tattaacctatttattatttatgtatttatttaagcatcaaatatttgtgcaagaatttggaaaaatagaagatgaatca ttgattgaatagttataaagatgttatagtaaatttattttattttagatattaaatgatgttttattagataaatttca atcagggtttttagattaaacaaacaaacaattgggtacccagttaaattttcatttcagatatacaacaaataattttt tagtataagtacattattgtttatctgaaattttaattgaactaacaatcctagtttgatactcccagtcttgtcattgc cagctgtgttggtagtgctgtgttgaattacggaataatgagttagaactattaaaacagccaaaactccacagtcaata ttagtaatttcttgctggttgaaacttgtttattatgtacaaatagattcttataatattatttaaatgactgcattttt aaatacaaggctttatatttttaactttaaaaaaaaccgg (SEQ ID Nθ:11967) gaattctctctccagcagccctgccagatgcccgcccagcccctgcctcaggcggggagggcttcagggaagctcaccaa ggcagaagggcgggagagattgtcagagccccagctggtgtccagggactgaccgtgagcctgggtgaaagtgagttccc cgttggaggcaacagacgaggagaggatggaaggcctggcccccaagaatgagccctgaggttcagggagcggctggagt gagccggccccagatctccgtccagctgcgggtcccagaggcctgggttacactcgcagctcctgggggaggcccttgac gtgcctcagttcccaaacaggaaccctgggaaggaccagagaagtgcctattgcgcagtgagtgcccgacacagctgcat gtggccggtatcacagggccctgggtaaactgaggcaggcgacacagctgcatgtggccggtatcacagggccctgggta aactgaggcaggcgacacagctgcatgtggccggtatcacagggccctgggtaaactgaggcaggcgacacagctgcatg tggccgtatcacagggccctgggtaaactgaggcaggtgacacagctgcatgtggccggtatcacggggccctggataaa cagaggcaggcgacacagctgcatgtggccggtatcacggggccctgggtaaactgaggcaggcgaggccacccccatca agtccctcaggtctaggtttggcaggtttggcaaaaacacagcaacgctcggttaaatctgaatttcgggtaagtatatc ctgggcctcatttggaagagacttagattaaaaaaaaaacgtcgagaccagcccggccaacacggtgaaaccccgtctct actaaaaatacaaaaaattagccaggcgcagtggctcacgcctgtgatcccagcactctgggaggctgaggcaggcggat cacccgaggtcagatgttcaagaccagcctggccgacagggcgaaacactgtctctactacaaatacaaaaattagccgg gagtggtggcaggtgcctgtaatctcagctattcaggaggctgaggcaggagaatcacttgaacctgggaggcggaggtt gccgtgagccgggatcacgccaccgcactccagcctgggcgatagagcaagactctgtctccaaaaaaataaattaaaaa acccacattgattatctgacatttgaatgcgattgtgcatcctgaattttgtctggaggccccacccgagccaatccagc ^'gtcttgtcccccttctcccccttttcatcaacgccctgtgccaggggagaggaagtggagggcgctggccggccgtgggg caatgcaacggcctcccagcacagggctataagaggagccgggcgggcacggaggggcagagaccccggagccccagccc caccatgaccctcggccgccgactcgcgtgtcttttcctcgcctgtgtcctgccggccttgctgctggggggtgagtttt tgagtccaacctcccgctgctccctctgtcccgggttctgt (SEQ ID NO: 11968) agcttcatcctggagtcaacagattgggtttgaatcctggctctgtccctttctagctgtgtgtttggttgttactccac ctctctgagccttaatttcttcatcagtaaaagtaatattcacctcctagggttgttgggagggagaataagaacttcta aagtacccgaacctagcaactaggacactatatttgcaggcaagatgaagaggggtggggaagtaataggaaacagccca aatcgagagccataatagtctctctttacttagtgccagtgcaggcctgtgattctgttcttaaaaacgtctggggcaag ctgcaggaaagacccgagatagcttatgttctaccataagccttaagggaggaggactccaggcagggagacttaccatg gcacctctaagagaaagcctactgaccagagagaggtcagtcatgtactcccgtagcttcttagaatttctgatctgact cgctgcctctagagttgttcaggtggaaattggaaggctatagaggaattcggcagcatacagtggctcacgtctgtaat ccaaaatccaagcattttggaaggccaaagtaggaggatcacttaagcccaggagtttaagaccagcctaggcaaccgag tgagatccatctccactaaaaaattttaaaatttgccaggtatggtggtgtgcacctgtagccccagctactcaggagag tcagagaatcggcgcaccccggagttcgaggttgcagtgagccatgatcacgccactgtactccagcctgggtgacagag aagaccacctgtctcaaaaaacataaataaataaataaataaataggccgtgcgcagcggctcacgactgtaattccaac attttagaaggcggaggcagcggatcacctgaggtcaggagttcgggaccagcctgaccaacgtggtgaaaccccaactc tactaaaaatacataaattaggcggggcgtggtggtggccgcctgtaatcccagctactcggtaggctgcagcaggagaa tggtttgaacccgggaggcagaggttgcagtgagccaaaatcccctcactgcattccagcctgagactaaaaaaaagagg cgatttcccacatcggtggaaatttgagctgtttaaactctggatgcctttttcagttctaatattccagatctccttgg tggataaacacttcatttcccttctcctgagcagagctcctgagccctggcccgctggaacctgtcacttctaaaaaagt tcgaggtccggactgtctctcccggagccttgaggctgatgagacggagcgagagaggggccgggggcaatggagtctac tcgcgggcccagggaggcgccagagggccccgggaccgaccgcaagaataacttccttcctcttccgctaacttcccggc agggctacgctcagggtgggggccccgagggctggggcgtcggcttccccctggggatcccccgcttcagagaagccaag cgttagcgcagccaaagccggaggcagcgaagctccggcccggggtggcgctgggtcagggtaccttctcggcggtcccc tggccggccgaactcgcgcctggtgtcctgtcaccccgctccccgccctgagtgagcctgtcccctctcaggggcgcgcc cgagtcgctccgggttggctgccaggtccagagttaaactttcagccaatgaaaaagggcgcgagggctgacgcacggaa acgtcatgggaattcccccctccggggggccgagaaggggctttcccggccctgagccctgctggcaggcgaggtgtcgc gaccggtcccaggtgggtcgggcgcggagagaagccgcaaccagagccgccgccacggtgagtggctggattcagacccc tgggtggccgggacaagagaaaagagggaggagggcctttagcggacagcgcctggggctggagagcagcagctgcacac agccggaaagggcgcgcaggcgacgacactcggatccacgtcgacaccgttgtacaaagatacgcggacccgtacgtaca cctgtacctgtgctggcgcacacacggcagcgtccgtgcagtcgcactcgcacacacatgcacacggagacgtgcccacc ggtgcactggtgcctgcacccacacccttcacgcacaaactcaagatacgctcacccgtgtctgtacatcaagacaggcg ctgacacacacccacactgagaagctcgggattcacctatctacacacatgctcgcttgcacactcatgttgacgccatg gacacacaacatgcaaccaagcactacagccgaaacacacttgtggagctgtgatggagacacactcttgtattaggtgg ggggggggggggagcgtgcagagatctccctgtcgcctgcgcgcccagaaccggtgcggtgtgggaccagctgctgttgt gaggtttgggagagagagaaaaagagcccactccgaggaggagacacttttcccgcagccccagaatcgcgttctcgggg cagaaccccggggcctcccacaggaaagagccccgcctacaggctgttcgaaggggaggccgtccgacagcaggaatgtc cccccaaaagcccccggggtttatcagccgtggcctccctcctggcagaaaatcccaaggttgctccagaccgggggagg ggagcgggaggcggacttggccccagactgccagcctcctcccggccgtgaaagaccctcctgttccctgccctggaggg aggagggggcttaacccaccggggcttcccggattctcctagacctctgcccgctgaaaagcagcgggacgccgtagact gtcgagggccatcccgcccctcccgtcgcgagggcggggccagtggcgtcatttccaggcccgccccctccggccccgcc tccccttggtattttcgggactttcctaagctgctctaactttcctgccccttccccgccaagcccaactccggatctcg ctctccaccggatctcacccgccacacccggacaggcggctggaggaggtcggaccctcccccaaatctgggcccccatt ctcccgcccacccccatttagatctgaccccctcccccacgccactcctcccaactttaggcgggcgtctaaaattctgg gaagcagaacctggccggagccactagacagagccgggcctagcccagagacatggagagttgctacaacccagtgagtc atgccgcctgcccctgacccggccggctagcccctcgtgtctgtccacctgtctgcccgagccccctactgctgccttac acctgtatgcctcgcagatgctctcagcctgccagtctgtccatctgtctgcaactctgcctccaaaaggagctttctct tgggtctgaggaggaggggggagtgaccactgaagacttggaagatgggaggtggggctagtgtggggggtgctgagagt cggatgccacccccagtctgtctccaaaccagggtctggatggtattattgaatatgatgatttcaaattgaactcctcc attgtggaacccaaggagccagccccagaaacaggtcagcaagttcactaacctcccctagtctaaagcgggggagggag agcatgtgccctctctctgggggaggggtctgggagatcgtgtgctcagcaaggtctctctgtccccagctgatggcccc tacctggtgatcgtggaacagcctaagcaggttgagtgagcaaaagggagggatgtggaatggcttcagctttggggaca aatggggtagtgtagctggctggcatggaggagcattgccgaagaggcccacaggggattggatggtcactgctgctgat cagagtgctgtagttttggttcagggctactaccagcgactcgggtcactgctggcctgggtggtcttccctgatcacaa tgctactatgcccttgaccttcagagaggcttccgatttcgatatggctgtgaaggcccctcccatggaggactgcccgg tgcctccagtgagaagggccgaaagacctatcccactgtcaaggtgakccaggatggtgctggmgggtgggctaagtgga cagcatgcccaaggccctgacgtgacagtcccttgcctctcctagatctgtaactacgagggaccagccaagatcgaggt ggacctggtaacacacagtgacccacctcgtgctcatgcccacagtctggtgggcaagcaatgctcggagctggggatct gcgccgtttctgtggggcccaaggacatgactgcccagtaggtgcccttcttacgccttggcccccactggtatgccskt c tgccagtcccaggccccagccacctccatatgatgttagcatctgaccaaggggaaangatgtaggttggccccaaac ccaagggcctaagtagaaactccaatggcttccttgaggaagtaaggctgagctgagcctggcaatgggaaaggtgcctg gcaatgggaaaggtgcctcaggaagaaagaactgcatggccaaaggctcccgattctctcttctcagatttaacaacctg ggtgtcctgcatgtgactaagaagaacatgatggggactatgatacaaaaacttcagaggcagcggctccgctctaggcc ccagggccttacgggtatgggtgcagggggtgggtcgggtatgggtgcagggggtgggtgggtcatgggaggtgctcatg gaaggagcagggagggagaagccaggggtcacacatgtacctactgcccagaggccgagcagcgggagctggagcaagag gccaaagaactgaagaaggtgatggatctgagtatagtgcggctgcgcttctctgccttccttagagccagtgatggctc cttctccctgcccctgaagccagtcacctcccagcccatccatgatagcagtgagtatcctgattgcctggggtgccagg cctggtsgsagaggtggcatgaggggtgacctcaagctgtgcagtcaaacaagacccaggtttcagaacctgcsctgcca catatgagctgagtgatcctgagcaagtcatttccccccc (SEQ ID NO: 11969) ggccaccggagcggcccggcgacgatcgctgacagcttcccctgcccttcccgtcggtcgggccgccagccgccgcagcc ctcggcctgcacgcagccaccggccccgctcccggagcccagcgccgccgaggccgcagccgcccggccagtaaggcggc gccgcccgcggccaccgcgggccctgccgttccctccgccgcgctgcgccatggcgcggcgctgactggcctggcccggc cccgccgcgctcccgctcgccccgacccgcactcgggcccgcccgggctccggcctgccgccgcctcttccttctccagc cggcaggccccgccgcttaggagggagagcccacccgcgccaggaggccgaacgcggactcgccacccggcttcagaatg gcagaagatgatccatatttgggaaggcctgaacaaatgtttcatttggatccttctttgactcatacaatatttaatcc agaagtatttcaaccacagatggcactgccaacagatggcccataccttcaaatattagagcaacctaaacagagaggat ttcgtttccgttatgtatgtgaaggcccatcccatggtggactacctggtgcctctagtgaaaagaacaagaagtcttac cctcaggtcaaaatctgcaactatgtgggaccagcaaaggttattgttcagttggtcacaaatggaaaaaatatccacct gcatgcccacagcctggtgggaaaacactgtgaggatgggatctgcactgtaactgctggacccaaggacatggtggtcg gcttcgcaaacctgggtatacttcatgtgacaaagaaaaaagtatttgaaacactggaagcacgaatgacagaggcgtgt ataaggggctataatcctggactcttggtgcaccctgaccttgcctatttgcaagcagaaggtggaggggaccggcagct gggagatcgggaaaaagagctaatccgccaagcagctctgcagcagaccaaggagatggacctcagcgtggtgcggctca tgtttacagcttttcttccggatagcactggcagcttcacaaggcgcctggaacccgtggtatcagacgccatctatgac agtaaagcccccaatgcatccaacttgaaaattgtaagaatggacaggacagctggatgtgtgactggaggggaggaaat ttatcttctttgtgacaaagttcagaaagatgacatccagattcgattttatgaagaggaagaaaatggtggagtctggg aaggatttggagatttttcccccacagatgttcatagacaatttgccattgtcttcaaaactccaaagtataaagatatt aatattacaaaaccagcctctgtgtttgtccagcttcggaggaaatctgacttggaaactagtgaaccaaaacctttcct ctactatcctgaaatcaaagataaagaagaagtgcagaggaaacgtcagaagctcatgcccaatttttcggatagtttcg gcggtggtagtggtgccggagctggaggcggaggcatgtttggtagtggcggtggaggagggggcactggaagtacaggt ccaggg atagcttcccacactatggatttcctacttatggtgggattactttccatcctggaactactaaatctaatgc tgggatgaagcatggaaccatggacactgaatctaaaaaggaccctgaaggttgtgacaaaagtgatgacaaaaacactg taaacctctttgggaaagttattgaaaccacagagcaagatcaggagcccagcgaggccaccgttgggaatggtgaggtc actctaacgtatgcaacaggaacaaaagaagagagtgctggagttcaggataacctctttctagagaaggctatgcagct tgcaaagaggcatgccaatgcccttttcgactacgcggtgacaggagacgtgaagatgctgctggccgtccagcgccatc tcactgctgtgcaggatgagaatggggacagtgtcttacacttagcaatcatccaccttcattctcaacttgtgagggat ctactagaagtcacatctggtttgatttctgatgacattatcaacatgagaaatgatctgtaccagacgcccttgcactt ggcagtgatcactaagcaggaagatgtggtggaggatttgctgagggctggggccgacctgagccttctggaccgcttgg gtaactctgttttgcacctagctgccaaagaaggacatgataaagttctcagtatcttactcaagcacaaaaaggcagca ctacttcttgaccaccccaacggggacggtctgaatgccattcatctagccatgatgagcaatagcctgccatgtttgct gctgctggtggccgctggggctgacgtcaatgctcaggagcagaagtccgggcgcacagcactgcacctggctgtggagc acgacaacatctcattggcaggctgcctgctcctggagggtgatgcccatgtggacagtactacctacgatggaaccaca cccctgcatatagcagctgggagagggtccaccaggctggcagctcttctcaaagcagcaggagcagatcccctggtgga gaactttgagcctctctatgacctggatgactcttgggaaaatgcaggagaggatgaaggagttgtgcctggaaccacgc ctctagatatggccaccagctggcaggtatttgacatattaaatgggaaaccatatgagccagagtttacatctgatgat ttactagcacaaggagacatgaaacagctggctgaagatgtgaagctgcagctgtataagttactagaaattcctgatcc agacaaaaactgggctactctggcgcagaaattaggtctggggatacttaataatgccttccggctgagtcctgctcctt ccaaaacacttatggacaactatgaggtctctgggggtacagtcagagagctggtggaggccctgagacaaatgggctac accgaagcaattgaagtgatccaggcagcctccagcccagtgaagaccacctctcaggcccactcgctgcctctctcgcc tgcctccacaaggcagcaaatagacgagctccgagacagtgacagtgtctgcgacacgggcgtggagacatccttccgca aactcagctttaccgagtctctgaccagtggtgcctcactgctaactctcaacaaaatgccccatgattatgggcaggaa ggacctctagaaggcaaaatttagcctgctgacaatttcccacaccgtgtaaaccaaagccctaaaattccactgcgttg tccacaagacagaagctgaagtgcatccaaaggtgctcagagagccggcccgcctgaatcattctcgatttaactcgaga ccttttcaacttggcttcctttcttggttcataaatgaattttagtttggttcacttacagatagtatctagcaatcaca acactggctgagcggatgcatctggggatgaggttgcttactaagctttgccagctgctgctggatcacagctgctttct gttgtcattgctgttgtccctctgc (SEQ ID NO: 11970) actttcctgccccttccccggccaagcccaactccggatctcgctctccaccggatctcacccgccacacccggacaggc ggctggaggaggcgggcgtctaaaattctgggaagcagaacctggccggagccactagacagagccgggcctagcccaga gacatggagagttgctacaacccaggtctggatggtattattgaatatgatgatttcaaattgaactcctccattgtgga acccaaggagccagccccagaaacagctgatggcccctacctggtgatcgtggaacagcctaagcagagaggcttccgat ttcgatatggctgtgaaggcccctcccatggaggactgcccggtgcctccagtgagaagggccgaaagacctatcccact gtcaagatctgtaactacgagggaccagccaagatcgaggtggacctggtaacacacagtgacccacctcgtgctcatgc ccacagtctggtgggcaagcaatgctcggagctggggatctgcgccgtttctgtggggcccaaggacatgactgcccaat ttaacaacctgggtgtcctgcatgtgactaagaagaacatgatggggactatgatacaaaaacttcagaggcagcggctc cgctctaggccccagggccttacggaggccgagcagcgggagctggagcaagaggccaaagaactgaagaaggtgatgga tctgagtatagtgcggctgcgcttctctgccttccttagagccagtgatggctccttctccctgcccctgaagccagtca cctcccagcccatccatgatagcaaatctccgggggcatcaaacctgaagatttctcgaatggacaagacagcaggctct gtgcggggtggagatgaagtttatctgctttgtgacaaggtgcagaaagatgacattgaggttcggttctatgaggatga tgagaatggatggcaggcctttggggacttctctcccacagatgtgcataaacagtatgccattgtgttccggacacccc cctatcacaagatgaagattgagcggcctgtaacagtgtttctgcaactgaaacgcaagcgaggaggggacgtgtctgat tccaaacagttcacctattaccctctggtggaagacaaggaagaggtgcagcggaagcggaggaaggccttgcccacctt ctcccagcccttcgggggtggctcccacatgggtggaggctctgggggtgcagccgggggctacggaggagctggaggag gtgagggggtactgatggagggaggggtaaaggtaagagaagctgtggaggaaaaaaatctgggggaggccgggcgtggc ttgcacgcctgtaatccagcctttgggaggccaaggcaggcagttacctgagatcaggagttcaagaccagcttggccaa cagcgtgaaacctcgtctctactaaaaatacaaacattagctgggcatggtggcaggcgcctgtaatcccagctactcgg gaggctgaggcaggagaatcgcttgaaccctgggagacaagaggttgcagtaagctgagatcacaccactgcactccagg ctgggcaataagagcgaaactccgtctcaaaaaaaaaaaaaaaaaaaaaa (SEQ ID NO: 11971) cacggtgagtggctggattcagacccctgggtggccgggacaagagaaaagagggaggagggcctttagcggacagcgcc tggggctggagagcagcagctgcacacagccggaaagggcgcgcaggcgacgacactcggatccacgtcgacaccgttgt acaaagatacgcggacccgcgggcgtctaaaattctgggaagcagaacctggccggagccactagacagagccgggccta gcccagagacatggagagttgctacaacccaggtctggatggtattattgaatatgatgatttcaaattgaactcctcca ttgtggaacccaaggagccagccccagaaacagctgatggcccctacctggtgatcgtggaacagcctaagcagagaggc ttccgatttcgatatggctgtgaaggcccctcccatggaggactgcccggtgcctccagtgagaagggccgaaagaccta tcccactgtcaagatctgtaactacgagggaccagccaagatcgaggtggacctggtaacacacagtgacccacctcgtg ctcatgcccacagtctggtgggcaagcaatgctcggagctggggatctgcgccgtttctgtggggcccaaggacatgact gcccaatttaacaacctgggtgtcctgcatgtgactaaggagaacatgatggggactatgatacaaaaacttcagaggca gcggctccgctctaggccccagggccttacggaggccgagcagcgggagctggagcaagaggccaaagaactgaagaagg tgatggatctgagtatagtgcggctgcgcttctctgccttccttagagccagtgatggctccttctccctgcccctgaag ccagtcatctcccagcccatccatgacagcaaatctccgggggcatcaaacctgaagatttctcgaatggacaagacagc aggctctgtgcggggtggagatgaagtttatctgctttgtgacaaggtgcagaaagatgacattgaggttcggttctatg aggatgatgagaatggatggcaggcctttggggacttctctcccacagatgtgcataaacagtatgccattgtgttccgg acacccccctatcacaagatgaagattgagcggcctgtaacagtgtttctgcaactgaaacgcaagcgaggaggggacgt gtctgattccaaacagttcacctattaccctctggtggaagacaaggaagaggtgcagcggaagcggaggaaggccttgc ccaccttctcccagcccttcgggggtggctcccacatgggtggaggctctgggggtgcagccgggggctacggaggagct ggaggaggtggcagcctcggtttcttcccctcctccctggcctacagcccctaccagtccggcgcgggccccatgggctg ctacccgggaggcgggggcggggcgcagatggccgccacggtgcccagcagggactccggggaggaagccgcggagccga gcgccccctccaggaccccccagtgcgacgcgcaggccccggagatgctgcagcgagctcgagagtacaacgcgcgcctg ttcggcctggcgcagcgcagcgcccgagccctactcgactacggcgtcaccgcggaccggcgcgcgctgctggcgggaca gcgccacctgctgacggcgcaggacgagaacggagacacaccactgcacctagccatcatccacgggcagaccagtgtca ttgagcagatagtctatgtcatccaccacgcccaggacctcggcgttgtcaacctcaccaaccacctgcaccagacgccc ctgcacctggcggtgatcacggggcagacgagtgtggtgagctttctgctgcgggtaggtgcagacccagctctgctgga tcggcatggagactcagccatgcatctggcgctgcgggcaggcgctggtgctcctgagctgctgcgtgcactgcttcaga gtggagctcctgctgtgccccagctgttgcatatgcctgactttgagggactgtatccagtacacctggcggtccgagcc cgaagccctgagtgcctggatctgctggtggacagtggggctgaagtggaggccacagagcggcaggggggacgaacagc cttgcatctagccacagagatggaggagctggggttggtcacccatctggtcaccaagctccgggccaacgtgaacgctc gcacctttgcgggaaacacacccctgcacctggcagctggactggggtacccgaccctcacccgcctccttctgaaggct ggtgctgacatccatgctgaaaacgaggagcccctgtgcccactgccttcaccccctacctctgatagcgactcggactc tgaagggcctgagaaggacacccgaagcagcttccggggccacacgcctcttgacctcacttgcagcaccaaggtgaaga ccttgctgctaaatgctgctcagaacaccatggagccacccctgaccccgcccagcccagcagggccgggactgtcactt ggtgatacagctctgcagaacctggagcagctgctagacgggccagaagcccagggcagctgggcagagctggcagagcg tctggggctgcgcagcctggtagacacgtaccgacagacaacctcacccagtggcagcctcctgcgcagctacgagctgg ctggcggggacctggcaggtctactggaggccctgtctgacatgggcctagaggagggagtgaggctgctgaggggtcca gaaacccgagacaagctgcccagcacaacagaggtgaaggaagacagtgcgtacgggagccagtcagtggagcagaaggc agagaagctgggcccaccccctgagccaccaggagggctctgccacgggcacccccagcctcaggtgcactgacctgctg cctgcccccagcccccttcccggaccccctgtacagcgtccccacctatttcaaatcttatttaacaccccacacccacc cctcagttgggacaaataaaggattctcatgggaaggggaggacccctccttcccaacttaaaaaaaaaaaaa (SEQ ID NO: 11972) agcttcatcctggagtcaacagattgggtttgaatcctggctctgtccctttctagctgtgtgtttggttgttactccac ctctctgagccttaatt c tcatcagtaaaagtaatattcacctcctagggttgttgggagggagaataagaacttcta aagtacccgaacctagcaactaggacactatatttgcaggcaagatgaagaggggtggggaagtaataggaaacagccca aatcgagagccataatagtctctctttacttagtgccagtgcaggcctgtgattctgttcttaaaaacgtctggggcaag ctgcaggaaagacccgagatagcttatgttctaccataagccttaagggaggaggactccaggcagggagacttaccatg gcacctctaagagaaagcctactgaccagagagaggtcagtcatgtactcccgtagcttcttagaatttctgatctgact cgctgcctctagagttgttcaggtggaaattggaaggctatagaggaattcggcagcatacagtggctcacgtctgtaat ccaaaatccaagcattttggaaggccaaagtaggaggatcacttaagcccaggagtttaagaccagcctaggcaaccgag tgagatccatctccactaaaaaattttaaaatttgccaggtatggtggtgtgcacctgtagccccagctactcaggagag tcagagaatcggcgcaccccggagttcgaggttgcagtgagccatgatcacgccactgtactccagcctgggtgacagag aagaccacctgtctcaaaaaacataaataaataaataaataaataggccgtgcgcagcggctcacgactgtaattccaac attttagaaggcggaggcagcggatcacctgaggtcaggagttcgggaccagcctgaccaacgtggtgaaaccccaactc tactaaaaatacataaattaggcggggcgtggtggtggccgcctgtaatcccagctactcggtaggctgcagcaggagaa tggtttgaacccgggaggcagaggttgcagtgagccaaaatcccctcactgcattccagcctgagactaaaaaaaagagg cgatttcccacatcggtggaaatttgagctgtttaaactctggatgcctttttcagttctaatattccagatctccttgg tggataaacacttcatttcccttctcctgagcagagctcctgagccctggcccgctggaacctgtcacttctaaaaaagt tcgaggtccggactgtctctcccggagccttgaggctgatgagacggagcgagagaggggccgggggcaatggagtctac tcgcgggcccagggaggcgccagagggccccgggaccgaccgcaagaataacttccttcctcttccgctaacttcccggc agggctacgctcagggtgggggccccgagggctggggcgtcggcttccccctggggatcccccgcttcagagaagccaag cgttagcgcagccaaagccggaggcagcgaagctccggcccggggtggcgctgggtcagggtaccttctcggcggtcccc tggccggccgaactcgcgcctggtgtcctgtcaccccgctccccgccctgagtgagcctgtcccctctcaggggcgcgcc cgagtcgctccgggttggctgccaggtccagagttaaactttcagccaatgaaaaagggcgcgagggctgacgcacggaa acgtcatgggaattcccccctccggggggccgagaaggggctttcccggccctgagccctgctggcaggcgaggtgtcgc gaccggtcccaggtgggtcgggcgcggagagaagccgcaaccagagccgccgccacggtgagtggctggattcagacccc tgggtggccgggacaagagaaaagagggaggagggcctttagcggacagcgcctggggctggagagcagcagctgcacac agccggaaagggcgcgcaggcgacgacactcggatccacgtcgacaccgttgtacaaagatacgcggacccgtacgtaca cctgtacctgtgctggcgcacacacggcagcgtccgtgcagtcgcactcgcacacacatgcacacggagacgtgcccacc ggtgcactggtgcctgcacccacacccttcacgcacaaactcaagatacgctcacccgtgtctgtacatcaagacaggcg ctgacacacacccacactgagaagctcgggattcacctatctacacacatgctcgcttgcacactcatgttgacgccatg gacacacaacatgcaaccaagcactacagccgaaacacacttgtggagctgtgatggagacacactcttgtattaggtgg ggggggggggggagcgtgcagagatctccctgtcgcctgcgcgcccagaaccggtgcggtgtgggaccagctgctgttgt gaggtttgggagagagagaaaaagagcccactccgaggaggagacacttttcccgcagccccagaatcgcgttctcgggg cagaaccccggggcctcccacaggaaagagccccgcctacaggctgttcgaaggggaggccgtccgacagcaggaatgtc cccccaaaagcccccggggtttatcagccgtggcctccctcctggcagaaaatcccaaggttgctccagaccgggggagg ggagcgggaggcggacttggccccagactgccagcctcctcccggccgtgaaagaccctcctgttccctgccctggaggg aggagggggcttaacccaccggggcttcccggattctcctagacctctgcccgctgaaaagcagcgggacgccgtagact gtcgagggccatcccgcccctcccgtcgcgagggcggggccagtggcgtcatttccaggcccgccccctccggccccgcc tccccttggtattttcgggactttcctaagctgctctaactttcctgccccttccccgccaagcccaactccggatctcg ctctccaccggatctcacccgccacacccggacaggcggctggaggaggtcggaccctcccccaaatctgggcccccatt ctcccgcccacccccatttagatctgaccccctcccccacgccactcctcccaactttaggcgggcgtctaaaattctgg gaagcagaacctggccggagccactagacagagccgggcctagcccagagacatggagagttgctacaacccagtgagtc atgccgcctgcccctgacccggccggctagcccctcgtgtctgtccacctgtctgcccgagccccctactgctgccttac acctgtatgcctcgcagatgctctcagcctgccagtctgtccatctgtctgcaactctgcctccaaaaggagctttctct tgggtctgaggaggaggggggagtgaccactgaagacttggaagatgggaggtggggctagtgtggggggtgctgagagt cggatgccacccccagtctgtctccaaaccagggtctggatggtattattgaatatgatgatttcaaattgaactcctcc attgtggaacccaaggagccagccccagaaacaggtcagcaagttcactaacctcccctagtctaaagcgggggagggag agcatgtgccctctctctgggggaggggtctgggagatcgtgtgctcagcaaggtctctctgtccccagctgatggcccc tacctggtgatcgtggaacagcctaagcaggttgagtgagcaaaagggagggatgtggaatggcttcagctttggggaca aatggggtagtgtagctggctggcatggaggagcattgccgaagaggcccacaggggattggatggtcactgctgctgat cagagtgctgtagttttggttcagggctactaccagcgactcgggtcactgctggcctgggtggtcttccctgatcacaa tgctactatgcccttgaccttcagagaggcttccgatttcgatatggctgtgaaggcccctcccatggaggactgcccgg tgcctccagtgagaagggccgaaagacctatcccactgtcaaggtgakccaggatggtgctggmgggtgggctaagtgga cagcatgcccaaggccctgacgtgacagtcccttgcctctcctagatctgtaactacgagggaccagccaagatcgaggt ggacctggtaacacacagtgacccacctcgtgctcatgcccacagtctggtgggcaagcaatgctcggagctggggatct gcgccgtttctgtggggcccaaggacatgactgcccagtaggtgcccttcttacgccttggcccccactggtatgccskt cwtgccagtcccaggccccagccacctccatatgatgttagcatctgaccaaggggaaangatgtaggttggccccaaac ccaagggcctaagtagaaactccaatggcttccttgaggaagtaaggctgagctgagcctggcaatgggaaaggtgcctg gcaatgggaaaggtgcctcaggaagaaagaactgcatggccaaaggctcccgattctctcttctcagatttaacaacctg ggtgtcctgcatgtgactaagaagaacatgatggggactatgatacaaaaacttcagaggcagcggctccgctctaggcc ccagggccttacgggtatgggtgcagggggtgggtcgggtatgggtgcagggggtgggtgggtcatgggaggtgctcatg gaaggagcagggagggagaagccaggggtcacacatgtacctactgcccagaggccgagcagcgggagctggagcaagag gccaaagaactgaagaaggtgatggatctgagtatagtgcggctgcgcttctctgccttccttagagccagtgatggctc cttctccctgcccctgaagccagtcacctcccagcccatccatgatagcagtgagtatcctgattgcctggggtgccagg cctggtsgsagaggtggcatgaggggtgacctcaagctgtgcagtcaaacaagacccaggtttcagaacctgcsctgcca catatgagctgagtgatcctgagcaagtcatttcccccccggccaccggagcggcccggcgacgatcgctgacagcttcc cctgcccttcccgtcggtcgggccgccagccgccgcagccctcggcctgcacgcagccaccggccccgctcccggagccc agcgccgccgaggccgcagccgcccggccagtaaggcggcgccgcccgcggccaccgcgggccctgccgttccctccgcc gcgctgcgccatggcgcggcgctgactggcctggcccggccccgccgcgctcccgctcgccccgacccgcactcgggccc gcccgggctccggcctgccgccgcctcttccttctccagccggcaggccccgccgcttaggagggagagcccacccgcgc caggaggccgaacgcggactcgccacccggcttcagaatggcagaagatgatccatatttgggaaggcctgaacaaatgt ttcatttggatccttctttgactcatacaatatttaatccagaagtatttcaaccacagatggcactgccaacagatggc ccataccttcaaatattagagcaacctaaacagagaggatttcgtttccgttatgtatgtgaaggcccatcccatggtgg actacctggtgcctctagtgaaaagaacaagaagtcttaccctcaggtcaaaatctgcaactatgtgggaccagcaaagg ttattgttcagttggtcacaaatggaaaaaatatccacctgcatgcccacagcctggtgggaaaacactgtgaggatggg atctgcactgtaactgctggacccaaggacatggtggtcggcttcgcaaacctgggtatacttcatgtgacaaagaaaaa agtatttgaaacactggaagcacgaatgacagaggcgtgtataaggggctataatcctggactcttggtgcaccctgacc ttgcctatttgcaagcagaaggtggaggggaccggcagctgggagatcgggaaaaagagctaatccgccaagcagctctg cagcagaccaaggagatggacctcagcgtggtgcggctcatgtttacagcttttcttccggatagcactggcagcttcac aaggcgcctggaacccgtggtatcagacgccatctatgacagtaaagcccccaatgcatccaacttgaaaattgtaagaa tggacaggacagctggatgtgtgactggaggggaggaaatttatcttctttgtgacaaagttcagaaagatgacatccag attcgattttatgaagaggaagaaaatggtggagtctgggaaggatttggagatttttcccccacagatgttcatagaca atttgccattgtcttcaaaactccaaagtataaagatattaatattacaaaaccagcctctgtgtttgtccagcttcgga ggaaatctgacttggaaactagtgaaccaaaacctttcctctactatcctgaaatcaaagataaagaagaagtgcagagg aaacgtcagaagctcatgcccaatttttcggatagtttcggcggtggtagtggtgccggagctggaggcggaggcatgtt tggtagtggcggtggaggagggggcactggaagtacaggtccagggtatagcttcccacactatggatttcctacttatg gtgggattactttccatcctggaactactaaatctaatgctgggatgaagcatggaaccatggacactgaatctaaaaag gaccctgaaggttgtgacaaaagtgatgacaaaaacactgtaaacctctttgggaaagttattgaaaccacagagcaaga tcaggagcccagcgaggccaccgttgggaatggtgaggtcactctaacgtatgcaacaggaacaaaagaagagagtgctg gagttcaggataacctctttctagagaaggctatgcagcttgcaaagaggcatgccaatgcccttttcgactacgcggtg acaggagacgtgaagatgctgctggccgtccagcgccatctcactgctgtgcaggatgagaatggggacagtgtcttaca cttagcaatcatccaccttcattctcaacttgtgagggatctactagaagtcacatctggtttgatttctgatgacatta tcaacatgagaaatgatctgtaccagacgcccttgcacttggcagtgatcactaagcaggaagatgtggtggaggatttg ctgagggctggggccgacctgagccttctggaccgcttgggtaactctgttttgcacctagctgccaaagaaggacatga taaagttctcagtatcttactcaagcacaaaaaggcagcactacttcttgaccaccccaacggggacggtctgaatgcca ttcatctagccatgatgagcaatagcctgccatgtttgctgctgctggtggccgctggggctgacgtcaatgctcaggag cagaagtccgggcgcacagcactgcacctggctgtggagcacgacaacatctcattggcaggctgcctgctcctggaggg tgatgcccatgtggacagtactacctacgatggaaccacacccctgcatatagcagctgggagagggtccaccaggctgg cagctcttctcaaagcagcaggagcagatcccctggtggagaactttgagcctctctatgacctggatgactcttgggaa aatgcaggagaggatgaaggagttgtgcctggaaccacgcctctagatatggccaccagctggcaggtatttgacatatt aaatgggaaaccatatgagccagagtttacatctgatgatttactagcacaaggagacatgaaacagctggctgaagatg tgaagctgcagctgtataagttactagaaattcctgatccagacaaaaactgggctactctggcgcagaaattaggtctg gggatacttaataatgccttccggctgagtcctgctccttccaaaacacttatggacaactatgaggtctctgggggtac agtcagagagctggtggaggccctgagacaaatgggctacaccgaagcaattgaagtgatccaggcagcctccagcccag tgaagaccacctctcaggcccactcgctgcctctctcgcctgcctccacaaggcagcaaatagacgagctccgagacagt gacagtgtctgcgacacgggcgtggagacatccttccgcaaactcagctttaccgagtctctgaccagtggtgcctcact gctaactctcaacaaaatgccccatgattatgggcaggaaggacctctagaaggcaaaatttagcctgctgacaatttcc cacaccgtgtaaaccaaagccctaaaattccactgcgttgtccacaagacagaagctgaagtgcatccaaaggtgctcag agagccggcccgcctgaatcattctcgatttaactcgagaccttttcaacttggcttcctttcttggttcataaatgaat tttagtttggttcacttacagatagtatctagcaatcacaacactggctgagcggatgcatctggggatgaggttgctta ctaagctttgccagctgctgctggatcacagctgctttctgttgtcattgctgttgtccctctgcactttcctgcccctt ccccggccaagcccaactccggatctcgctctccaccggatctcacccgccacacccggacaggcggctggaggaggcgg gcgtctaaaattctgggaagcagaacctggccggagccactagacagagccgggcctagcccagagacatggagagttgc tacaacccaggtctggatggtattattgaatatgatgatttcaaattgaactcctccattgtggaacccaaggagccagc cccagaaacagctgatggcccctacctggtgatcgtggaacagcctaagcagagaggcttccgatttcgatatggctgtg aaggcccctcccatggaggactgcccggtgcctccagtgagaagggccgaaagacctatcccactgtcaagatctgtaac tacgagggaccagccaagatcgaggtggacctggtaacacacagtgacccacctcgtgctcatgcccacagtctggtggg caagcaatgctcggagctggggatctgcgccgtttctgtggggcccaaggacatgactgcccaatttaacaacctgggtg tcctgcatgtgactaagaagaacatgatggggactatgatacaaaaacttcagaggcagcggctccgctctaggccccag ggccttacggaggccgagcagcgggagctggagcaagaggccaaagaactgaagaaggtgatggatctgagtatagtgcg gctgcgcttctctgccttccttagagccagtgatggctccttctccctgcccctgaagccagtcacctcccagcccatcc atgatagcaaatctccgggggcatcaaacctgaagatttctcgaatggacaagacagcaggctctgtgcggggtggagat gaagtttatctgctttgtgacaaggtgcagaaagatgacattgaggttcggttctatgaggatgatgagaatggatggca ggcctttggggacttctctcccacagatgtgcataaacagtatgccattgtgttccggacacccccctatcacaagatga agattgagcggcctgtaacagtgtttctgcaactgaaacgcaagcgaggaggggacgtgtctgattccaaacagttcacc tattaccctctggtggaagacaaggaagaggtgcagcggaagcggaggaaggccttgcccaccttctcccagcccttcgg gggtggctcccacatgggtggaggctctgggggtgcagccgggggctacggaggagctggaggaggtgagggggtactga tggagggaggggtaaaggtaagagaagctgtggaggaaaaaaatctgggggaggccgggcgtggcttgcacgcctgtaat ccagcctttgggaggccaaggcaggcagttacctgagatcaggagttcaagaccagcttggccaacagcgtgaaacctcg tctctactaaaaatacaaacattagctgggcatggtggcaggcgcctgtaatcccagctactcgggaggctgaggcagga gaatcgcttgaaccctgggagacaagaggttgcagtaagctgagatcacaccactgcactccaggctgggcaataagagc gaaactccgtctcaaaaaaaaaaaaaaaaaaaaaacacggtgagtggctggattcagacccctgggtggccgggacaaga gaaaagagggaggagggcctttagcggacagcgcctggggctggagagcagcagctgcacacagccggaaagggcgcgca ggcgacgacactcggatccacgtcgacaccgttgtacaaagatacgcggacccgcgggcgtctaaaattctgggaagcag aacctggccggagccactagacagagccgggcctagcccagagacatggagagttgctacaacccaggtctggatggtat tattgaatatgatgatttcaaattgaactcctccattgtggaacccaaggagccagccccagaaacagctgatggcccct acctggtgatcgtggaacagcctaagcagagaggcttccgatttcgatatggctgtgaaggcccctcccatggaggactg cccggtgcctccagtgagaagggccgaaagacctatcccactgtcaagatctgtaactacgagggaccagccaagatcga ggtggacctggtaacacacagtgacccacctcgtgctcatgcccacagtctggtgggcaagcaatgctcggagctgggga tctgcgccgtttctgtggggcccaaggacatgactgcccaatttaacaacctgggtgtcctgcatgtgactaaggagaac atgatggggactatgatacaaaaacttcagaggcagcggctccgctctaggccccagggccttacggaggccgagcagcg ggagctggagcaagaggccaaagaactgaagaaggtgatggatctgagtatagtgcggctgcgcttctctgccttcctta gagccagtgatggctccttctccctgcccctgaagccagtcatctcccagcccatccatgacagcaaatctccgggggca tcaaacctgaagatttctcgaatggacaagacagcaggctctgtgcggggtggagatgaagtttatctgctttgtgacaa ggtgcagaaagatgacattgaggttcggttctatgaggatgatgagaatggatggcaggcctttggggacttctctccca cagatgtgcataaacagtatgccattgtgttccggacacccccctatcacaagatgaagattgagcggcctgtaacagtg tttctgcaactgaaacgcaagcgaggaggggacgtgtctgattccaaacagttcacctattaccctctggtggaagacaa ggaagaggtgcagcggaagcggaggaaggccttgcccaccttctcccagcccttcgggggtggctcccacatgggtggag gctctgggggtgcagccgggggctacggaggagctggaggaggtggcagcctcggtttcttcccctcctccctggcctac agcccctaccagtccggcgcgggccccatgggctgctacccgggaggcgggggcggggcgcagatggccgccacggtgcc cagcagggactccggggaggaagccgcggagccgagcgccccctccaggaccccccagtgcgacgcgcaggccccggaga tgctgcagcgagctcgagagtacaacgcgcgcctgttcggcctggcgcagcgcagcgcccgagccctactcgactacggc gtcaccgcggaccggcgcgcgctgctggcgggacagcgccacctgctgacggcgcaggacgagaacggagacacaccact gcacctagccatcatccacgggcagaccagtgtcattgagcagatagtctatgtcatccaccacgcccaggacctcggcg ttgtcaacctcaccaaccacctgcaccagacgcccctgcacctggcggtgatcacggggcagacgagtgtggtgagcttt ctgctgcgggtaggtgcagacccagctctgctggatcggcatggagactcagccatgcatctggcgctgcgggcaggcgc tggtgctcctgagctgctgcgtgcactgcttcagagtggagctcctgctgtgccccagctgttgcatatgcctgactttg agggactgtatccagtacacctggcggtccgagcccgaagccctgagtgcctggatctgctggtggacagtggggctgaa gtggaggccacagagcggcaggggggacgaacagccttgcatctagccacagagatggaggagctggggttggtcaccca tctggtcaccaagctccgggccaacgtgaacgctcgcacctttgcgggaaacacacccctgcacctggcagctggactgg ggtacccgaccctcacccgcctccttctgaaggctggtgctgacatccatgctgaaaacgaggagcccctgtgcccactg ccttcaccccctacctctgatagcgactcggactctgaagggcctgagaaggacacccgaagcagcttccggggccacac gcctcttgacctcacttgcagcaccaaggtgaagaccttgctgctaaatgctgctcagaacaccatggagccacccctga ccccgcccagcccagcagggccgggactgtcacttggtgatacagctctgcagaacctggagcagctgctagacgggcca gaagcccagggcagctgggcagagctggcagagcgtctggggctgcgcagcctggtagacacgtaccgacagacaacctc acccagtggcagcctcctgcgcagctacgagctggctggcggggacctggcaggtctactggaggccctgtctgacatgg gcctagaggagggagtgaggctgctgaggggtccagaaacccgagacaagctgcccagcacaacagaggtgaaggaagac agtgcgtacgggagccagtcagtggagcagaaggcagagaagctgggcccaccccctgagccaccaggagggctctgcca cgggcacccccagcctcaggtgcactgacctgctgcctgcccccagcccccttcccggaccccctgtacagcgtccccac ctatttcaaatcttatttaacaccccacacccacccctcagttgggacaaataaaggattctcatgggaaggggaggacc cctccttcccaacttaaaaaaaaaaaaa (SEQ ID NO: 11973) atgacagcaaaagattcttcaaaggaacttactgcttctgaacctgaggtttgcataaagactttcaaggagcaaatgca tttagaacttgagcttccgagattaccaggaaacagacctacatctcctaaaatttctccacgcagttcaccaaggaact caccatgctttttcagaaagttactggtgaataaaagcattcggcagcgtcgtcgcttcactgtggctcatacatgcttt gatgtggaaaatggcccttccccaggtcggagtccactggatccccaggccagctcttccgctgggctggtacttcacgc cacctttcctgggcacagccagcgcagagagtcatttctctacagatcagacagcgactatgacttgtcaccaaaggcga tgtcgagaaactcttctcttccaagcgagcaacacggcgatgacttgattgtaactccttttgcccaggtccttgccagc ttgcgaagtgtgagaaacaacttcactatactgacaaaccttcatggtacatctaacaagaggtccccagctgctagtca gcctcctgtctccagagtcaacccacaagaagaatcttatcaaaaattagcaatggaaacgctggaggaattagactggt gt tagaccagctagagaccatacagacctaccggtctgtcagtgagatggcttctaacaagttcaaaagaatgctgaac cgggagctgacacacctctcagagatgagccgatcagggaaccaggtgtctgaatacatttcaaatactttcttagacaa gcagaatgatgtggagatcccatctcctacccagaaagacagggagaaaaagaaaaagcagcagctcatgacccagataa gtggagtgaagaaattaatgcatagttcaagcctaaacaatacaagcatctcacgctttggagtcaacactgaaaatgaa gatcacctggccaaggagctggaagacctgaacaaatggggtcttaacatctttaatgtggctggatattctcacaatag acccctaacatgcatcatgtatgσtatattccaggaaagagacctcctaaagacattcagaatctca ctgacaca ta taacctacatgatgactttagaagaccattaccattctgacgtggcatatcacaacagcctgcacgctgctgatgtagcc cagtcgacccatgttctcctttctacaccagcattagacgctgtcttcacagatttggagatcctggctgccatttttgc agctgccatccatgacgttgatca cctggagtctccaatcagtttc catcaacacaaattcagaacttgctttgatgt ataatgatgaatctgtgttggaaaatcatcaccttgctgtgggtttcaaactgctgcaagaagaacactgtgacatcttc atgaatctcaccaagaagcagcgtcagacactcaggaagatggttattgacatggtgttagcaactgatatgtctaaaca tatgagcctgctggcagacctgaagacaatggtagaaacgaagaaagttacaagttcaggcgttcttctcctagacaact ataccgatcgcattcaggtccttcgcaacatggtacactgtgcagacctgagcaaccccaccaagtccttggaattgtat cggcaatggacagaccgcatcatggaggaatttttccagcagggagacaaagagcgggagaggggaatggaaattagccc aatgtgtgataaacacacagcttctgtggaaaaatcccaggttggtttcatcgactacattgtccatccattgtgggaga catgggcagatttggtacagcctgatgctcaggacattctcgataccttagaagataacaggaactggtatcagagcatg atacctcaaagtccctcaccaccactggacgagcagaacagggactgccagggtctgatggagaagtttcagtttgaact gactctcgatgaggaagattctgaaggacctgagaaggagggagagggacacagctatttcagcagcacaaagacgcttt gtgtgattgatccagaaaacagagattccctgggagagactgacatagacattgcaacagaagacaagtcccccgtggat aca (SEQ ID NO: 11974) tatcacaacagcatgcacgcagccgatgttacccagacagtccattgcttcttgctccgcacagggatggtgcactgcct gtcggagattgagctcctggccatcatctttgctgcagctatccatgattatgagcacacgggcactaccaacagct cc acatccagaccaagtcagaatgtgccatcgtgtacaatgatcgttcagtgctggagaatcaccacatcagctctgttttc cgattgatgcaggatgatgagatgaacattttcatcaacctcaccaaggatgagtttgtagaactccgagccctggtcat tgagatggtgttggctacagatatggca (SEQ ID NO.-11975) atgacagcaaaagattcttcaaaggaacttactgcttctgaacctgaggtttgcataaagactttcaaggagcaaatgca tttagaacttgagcttccgagattaccaggaaacagacctacatctcctaaaatttctccacgcagttcaccaaggaact caccatgctttttcagaaagttactggtgaataaaagcattcggcagcgtcgtcgcttcactgtggctcat catgcttt gatgtggaaaatggcccttccccaggtcggagtccactggatccccaggccagctcttccgctgggctggtacttcacgc cacctttcctgggcacagccagcgcagagagtcat tctctacagatcagacagcgactatgacttgtcaccaaaggcga tgtcgagaaactcttctcttccaagcgagcaacacggcgatgacttgattgtaactccttttgcccaggtccttgccagc ttgcgaagtgtgagaaacaacttcactatactgacaaaccttcatggtacatctaacaagaggtccccagctgctagtca gcctcctgtctccagagtcaacccacaagaagaatcttatcaaaaattagcaatggaaacgctggaggaattagactggt gtttagaccagctagagaccatacagacctaccggtctgtcagtgagatggcttctaacaagttcaaaagaatgctgaac cgggagctgacacacctctcagagatgagccgatcagggaaccaggtgtctgaatacatttcaaatactttcttagacaa gcagaatgatgtggagatcccatctcctacccagaaagacagggagaaaaagaaaaagcagcagctcatgacccagataa gtggagtgaagaaattaatgcatagttcaagcctaaacaatacaagcatctcacgctttggagtcaacactgaaaatgaa gatcacctggccaaggagctggaagacctgaacaaatggggtcttaacatctttaatgtggctggatattctcacaatag acccctaacatgcatcatgtatgctatattccaggaaagagacctcctaaagacattcagaatc catctgacacattta taacctacatgatgactttagaagaccattaccattctgacgtggcatatcacaacagcctgcacgctgctgatgtagcc cagtcgacccatgttctcctttctacaccagcattagacgctgtcttcacagatttggagatcctggctgccatttttgc agctgccatccatgacgttgatcatcctggagtctccaatcagtttctcatcaacacaaattcagaacttgctttgatgt ataatgatgaatctgtgttggaaaatcatcaccttgctgtgggtttcaaactgctgcaagaagaacactgtgacatcttc atgaatctcaccaagaagcagcgtcagacactcaggaagatggttattgacatggtgt agcaactgatatgtctaaaca tatgagcctgctggcagacctgaagacaatggtagaaacgaagaaagttacaagttcaggcgttcttctcctagacaact ataccgatcgcattcaggtccttcgcaacatggtacactgtgcagacctgagcaaccccaccaagtccttggaattgtat cggcaatggacagaccgcatcatggaggaatttttccagcagggagacaaagagcgggagaggggaatggaaattagccc aatgtgtgataaacacacagcttctgtggaaaaatcccaggttggtttcatcgactacattgtccatccattgtgggaga catgggcagatttggtacagcctgatgctcaggacattctcgataccttagaagataacaggaactggtatcagagcatg atacctcaaagtccctcaccaccactggacgagcagaacagggactgccagggtctgatggagaagtttcagtttgaact gactctcgatgaggaagattctgaaggacctgagaaggagggagagggacacagctatttcagcagcacaaagacgcttt gtgtgattgatccagaaaacagagattccctgggagagactgacatagacattgcaacagaagacaagtcccccgtggat acatatcacaacagcatgcacgcagccgatgttacccagacagtccattgcttcttgctccgcacagggatggtgcactg cctgtcggagattgagctcctggccatcatctttgctgcagctatccatgattatgagcacacgggcactaccaacagct tccacatccagaccaagtcagaatgtgccatcgtgtacaatgatcgttcagtgctggagaatcaccacatcagctctgtt ttccgattgatgcaggatgatgagatgaacattttcatcaacctcaccaaggatgagtttgtagaactccgagccctggt cattgagatggtgttggctacagatatggca (SEQ ID NO:11976) gggccgccgtcggcgcgctgggtgcgggaagggggctctggatttcggtccctcccctttttcctctgagtctcggaacg ctccagctctcagaccctcttcctcccaggtaaaggccgggagaggagggcgcatctcttttccaggcaccccaccatgg gcaatgcctccaatgactcccagtctgaggactgcgagacgcgacagtggcttcccccaggcgaaagcccagccatcagc tccgtcatgttctcggccggggtgctggggaacctcatagcactggcgctgctggcgcgccgctggcggggggacgtggg gtgcagcgccggccgcaggagctccctctccttgttccacgtgctggtgaccgagctggtgttcaccgacctgctcggga cctgcctcatcagcccagtggtactggcttcgtacgcgcggaaccagaccctggtggcactggcgcccgagagccgcgcg tgcacctacttcgctttcgccatgaccttcttcagcctggccacgatgctcatgctcttcgccatggccctggagcgcta cctctcgatcgggcacccctacttctaccagcgccgcgtctcggcctccgggggcctggccgtgctgcctgtcatctatg cagtctccctgctcttctgctcgctgccgctgctggactatgggcagtacgtccagtactgccccgggacctggtgcttc atccggcacgggcggaccgcttacctgcagctgtacgccaccctgctgctgcttctcattgtctcggtgctcgcctgcaa cttcagtgtcattctcaacctcatccgcatgcaccgccgaagccggagaagccgctgcggaccttccctgggcagtggcc ggggcggccccggggcccgcaggagaggggaaagggtgtccatggcggaggagacggaccacctca tctcctggctatc atgaccatcaccttcgccgtctgctccttgcctttcacgatttttgcatatatgaatgaaacctcttcccgaaaggaaaa atgggacctccaagctcttaggtttttatcaattaattcaataattgacccttgggtctttgccatccttaggcctcctg ttctgagactaatgcgttcagtcctctgttgtcggatttcattaagaacacaagatgcaacacaaacttcctgttctaca cagtcagatgccagtaaacaggctgacctttgaggtcagtagtttaaaagttcttagttatatagcatctggaagatcat tttgaaattgttccctggagaaatgaaaacagtgtgtaaacaaaatgaagctgccctaataaaaaggagtatacaaacat ttaagctgtggtcaaggctacagatgtgctgacaaggcacttcatgtaaagtgtcagaaggagctacaaaacctaccctc aatgagcatggtacttggcctttggaggaacaatcggctgcattgaagatccagctgcctattgatttaagctttcctgt tgaatgacaaagtatgtggttttgtaatttgtttgaaaccccaaacagtgactgtactttctattttaatcttgctacta ccgttatacacatatagtgtacagccagaccagattaaacttcatatgtaatctctaggaagtcaatatgtggaagcaac caagcctgctgtcttgtgatcacttagcgaaccctttatttgaacaatgaagttgaaaatcataggcaccttttactgtg atgtttgtgtatgtgggagtactctcatcactacagtattactcttacaagagtggactcagtgggttaacatcagtttt gtttactcatcctccaggaactgcaggtcaagttgtcaggttatttattttataatgtccatatgctaatagtgatcaag aagactttaggaatggttctctcaacaagaaataatagaaatgtctcaaggcagttaattctcattaatactcttattat cctatttctgggggaggatgtacgtggccatgtatgaagccaaatattaggcttaaaaactgaaaaatctggttcattct tcagatatactggaacccttttaaagttgatattggggccatgagtaaaatagattttataagatgactgtgttgtacca aaattcatctgtctatattttatttaggggaacatggtttgactcatcttatatgggaaaccatgtagcagtgagtcata tcttaatatatttctaaatgtttggcatgtaaatgtaaactcagcatcaaaatatttcagtgaatttgcactgtttaatc atagttactgtgtaaactcatctgaaatgttacaaaaataaactataaaaca (SEQ ID NO: 11977) gggggcggcagggctgagcggccggtgatggggaccccacatcccaggcagtgccggcacccctggcgcctgacatgagc ccttgcgggcccctcaacctgagcctggcgggcgaggcgaccacatgcgcggcgccctgggtccccaacacgtcggccgt gccgccgtcgggcgcttcgcccgcgctgcccatcttctccatgacgctgggcgccgtgtccaacctgctggcgctggcgc tgctggcgcaggccgcgggccgcctgcgacgccgccgctcggccaccaccttcctgctgttcgtggccagcctgctggcc accgacctggcgggccacgtgatcccgggcgcgctggtgctgcgtctgtacactgcggggcgcgctccggccggcggggc ctgccacttcctgggcggctgcatggtcttcttcggcctgtgcccgctgctgctgggctgtggcatggccgtggagcgct gcgtgggcgtcacgcggccgctgctccacgccgcgcgggtctcggtcgcccgcgcgcgcctggcgctggccgcggtggcc gcggtggccttggccgtggcgctgctgccgctggcgcgcgtgggccgctatgagctgcagtacccgggcacgtggtgctt catcggcctgggtcccccgggcggctggcgccaggcactgcttgctggcctcttcgccagcctcggcctggtcgcgctcc tcgccgcgctggtgtgcaacacgctcagcggcctggccctgcatcgcgcccgctggcgacgccgctcccgacggcctccc ccggcctcaggccccgacagccggcgtcgctggggggcgcacggaccccgctcggcctccgcctcgtccgcctcgtccat cgcttcggcctccaccttctttggcggctctcggagcagcggctcggcacgcagagctcgcgcccacgacgtggagatgg tgggccagcttgtcggtatcatggtggtgtcgtgcatctgctggagcccaatgctggtgttggtggcgctggccgtcggc ggctggagctctacctccctgcagcggccactgttcctggccgtgcgccttgcctcctggaaccagatcctggacccttg ggtgtacatcctactgcgccaggccgtgctgcgccaactgcttcgcctcttgcccccgagggccggagccaagggcggcc ccgcggggctgggcctaacaccgagcgcctgggaggccagctcgctgcgcagctcccggcacagcggcctcagccacttc taagcacaaccagaggcccaacgactaagccagcccaccctgggctgggcccaggtgcgcggcgcagagcctttgggaat aaaaagccattctgcg (SEQ ID NO: 11978) atgggcaatgcctccaatgactcccagtctgaggactgcgagacgcgacagtggcttcccccaggcgaaagcccagccat cagctccgtcatgttctcggccggggtgctggggaacctcatagcactggcgctgctggcgcgccgctggcggggggacg tggggtgcagcgccggccgcaggagctccctctccttgttccacgtgctggtgaccgagctggtgttcaccgacctgctc gggacctgcctcatcagcccagtggtactggcttcgtacgcgcggaaccagaccctggtggcactggcgcccgagagccg cgcgtgcacctacttcgctttcgccatgaccttcttcagcctggccacgatgctcatgctcttcgccatggccctggagc gctacctctcgatcgggcacccctacttctaccagcgccgcgtctcgcgctccgggggcctggccgtgctgcctgtcatc tatgcagtctccctgctcttctgctcgctgccgctgctggactatgggcagtacgtccagtactgccccgggacctggtg cttcatccggcacgggcggaccgcttacctgcagctgtacgccaccctgctgctgcttctcattgtctcggtgctcgcct gcaacttcagtgtcattctcaacctcatccgcatgcaccgccgaagccggagaagccgctgcggaccttccctgggcagt ggccggggcggccccggggcccgcaggagaggggaaagggtgtccatggcggaggagacggaccacctcattctcctggc tatcatgaccatcaccttcgccgtctgctccttgcctttcacgatttttgcatatatgaatgaaacctcttcccgaaagg aaaaatgggacctccaagctcttaggtttttatcaattaattcaataattgacccttgggtctttgccatccttaggcct cctgttctgagactaatgcgttcagtcctctgttgtcggatttcattaagaacacaagatgcaacacaaacttcctgttc tacacagtcagatgccagtaaacaggctgacctttga (SEQ ID NO: 11979) ctgcagatgggaagaggtttttccaggaatttaaattgtgcaataaggccacacaatcttacttaaaaaaaatggtgaag gggttttaattacaccatgaagttttacaattttttaggtttttagttctggttttagaaaacagagtagaaggattaac agagaaaaacttcaccattagacaagaagtcaaaatgattctaagggccgcgcaaacaggctttccaagaattaatcatg aggtggtgcttggagaattcctttactccagtgactttgaaacccccttctcactctccactagtctttcaaaggattca tggtgaattgggtctaacgagtataacacggccggccgaacgatgaagctcacgctaccctttcagggcggagaagttcc caggaggaagaatggagaaaaagatcgcagttaggcagtcctcccaacctcaccaaggctccacctctctccaaagccgc aacgtgctgccacctgcgccgggagaggctgcaatcactgtctcctcctctttctttctctttttttttttttctttttt gcctggggtgcccgaccaagcgcagccgcagtctgggcactgccaactgactccaactccttttatggtgagaggatgga ttcttcgttatttccccgcccaatctggtacccacccacccacccacccaccacgtccgctgggcgcacccaagtctaac cccggggcgcacgccgtagcgcagacaccgtatttctcctcctttctcggccaaccctaggtagaatcctaaaacaactg ccctctcttccacgatctagatgttgcggcccgcggacaggaggttcaagaaatagtacactccgagcggcaggcagcga gagcggaaacggtcgccggtttcagtggtggccccactggaagccgagttcaggagcggctaagcgtcgccggggaaagc accggggcttcccagggtctcctccgagttcccactccgcacctccgagggcgtgaaaaccacgggagccgcccgccccg cgcgcccagccccgccccagcccagacaccgccccccgccagtcttccctgcggcgcccagggaggacgccgtccgcccc cttccaatccggccaatgggcgcccgggcagcgcgcggtttgcctccgcctccgccagggaaacttggaggaggagaaaa gtttgtacagagggtggaaaggccgcagcacgcgagctcca (SEQ ID NO: 11980) agcccggcagcccgagaggaagatgaacagccccaggccagagcctctgcgagagtggaccccgagccgcccccaggtag ccaggagcggcctcagcggcagccgcaaactccagtagccgcccgtgctgcccgtgctggggcggagggcagccagagct ggggaccaaggctccgcgccacctgggcacagcctcacacctgaacgctgtcctcccgcagacgagaccggcgggcactg caaagctgggactcgtctttgaaggaaaaaaaatagcgagtaagaaatccagcaccattcttcactgacccatcccgctg cacctcttgtttcccaagtttttgaaagctggcaactctgacctcggtgtccaaaaatcgacagccactgagaccggctt tgagaagccgaagatttggcagtttccagactgagcaggacaaggtgaaagcaggttggaggcgggtccaggacatctga gggctgaccctgggggctcgtgaggctgccaccgctgctgccgctacaggtgagatggcgttgggctgacgttggggtca acgggtagagaacgagggatgccgccctcgccgaagagagccaagaggggaagagcgcgctctccaaattgcttttgtaa cttgttttcagtgagcattttattgattcagaatctatcgagaatagcactagcgagctactttccccttgagatgggtc ttattcatcttggcaatggagtgagttggattgtggggaggaagaggaatgggaaaatcagtttataaatattaatgtca gccaagagtgtgctgttggcaggacgtatcgcgagcctggagattttggtggccgcagttggtaagtggctacaatccag aaagtaggatcgagttgctccccttgtcttatcagtgtatcgtttctcgggcgcgggtctaacaccttacaagtggtaat ttccgctcacggcagctttgtctctcttctaccatccccagacccagccttgcactccaaggctgcgcaccgccagccac tatcatgtccactcccggggtcaattcgtccgcctccttgagccccgaccggctgaacagcccagtaaccatcccggcgg tgatgttcatcttcggggtggtgggcaacctggtggccatcgtggtgctgtgcaagtcgcgcaaggagcagaaggagacg accttctacacgctggtatgtgggctggctgtcaccgacctgttgggcactttgttggtgagcccggtgaccatcgccac gtacatgaagggccaatggcccgggggccagccgctgtgcgagtacagcaccttcattctgctcttcttcagcctgtccg gcctcagcatcatctgcgccatgagtgtcgagcgctacctggccatcaaccatgcctatttctacagccactacgtggac aagcgattggcgggcctcacgctctttgcagtctatgcgtccaacgtgctcttttgcgcgctgcccaacatgggtctcgg tagctcgcggctgcagtacccagacacctggtgcttcatcgactggaccaccaacgtgacggcgcacgccgcctactcct acatgtacgcgggcttcagctccttcctcattctcgccaccgtcctctgcaacgtgcttgtgtgcggcgcgctgctccgc atgcaccgccagttcatgcgccgcacctcgctgggcaccgagcagcaccacgcggccgcggccgcctcggttgcctcccg gggccaccccgctgcctccccagccttgccgcgcctcagcgactttcggcgccgccggagcttccgccgcatcgcgggcg ccgagatccagatggtcatcttactcattgccacctccctggtggtgctcatctgctccatcccgctcgtggtgagtgac cgggggtggggccctactcggcctttttctcgcatccacctcccgcgtccattccccgctccctgttttccctctgagtc cttgggagtgaacgtgtcgcctttaggtcggggctgggattcccacactgtttctcagaggaggcccaacccctctttgg aagtcccaaccctaacgcgatttagcaggtgctttggccctacatcccccagtttatgtttcccggaaggctgg ('SEQ ID NO: 11981) agcccatgactggtttttctgaggcttattatgtagcttcctcttttcctggaacttgttaccagaaatgaaggcagctt cctaatattgataaggtagacatagcatttatatgttttcccaattgattaatgatgaaatctaaatgtgcgactcactt atgcaggtgcgagtattcgtcaaccagttatatcagccaagtttggagcgagaagtcagtaaaaatccagatttgcaggc catccgaattgcttctgtgaaccccatcctagacccctggatata atcctcctgagaaagacagtgctcagtaaagcaa tagagaagatcaaatgcctcttctgccgcattggcgggtcccgcagggagcgctccggacagcactgctcagacagtcaa aggacatcttctgccatgtcaggccactctcgctccttcatctcccgggagctgaaggagatcagcagtacatctcagac cctcctgccagacctctcactgccagacctcagtgaaaatggccttggaggcaggaatttgcttccaggtgtgcctggca tgggcctggcccaggaagacaccacctcactgaggactttgcgaatatcagagacctcagactcttcacagggtcaggac tcagagagtgtgttactggtggatgaggctggtggaagcggcagggcagggcctgcccctaaggggagctccctgcaagt cacatttcccagtgaaacactgaacttatcagaaaaatgtatataataggcaaggaaagaaatacagtactgtttctgga cccttataaaatcctgtgcaatagacacatacatgtcaca (SEQ ID NO: 11982) gggccgccgtcggcgcgctgggtgcgggaagggggctctggatttcggtccctcccctttttcctctgagtctcggaacg ctccagctctcagaccctcttcctcccaggtaaaggccgggagaggagggcgcatctcttttccaggcaccccaccatgg gcaatgcctccaatgactcccagtctgaggactgcgagacgcgacagtggcttcccccaggcgaaagcccagccatcagc tccgtcatgttctcggccggggtgctggggaacctcatagcactggcgctgctggcgcgccgctggcggggggacgtggg gtgcagcgccggccgcaggagctccctctccttgttccacgtgctggtgaccgagctggtgttcaccgacctgctcggga cctgcctcatcagcccagtggtactggcttcgtacgcgcggaaccagaccctggtggcactggcgcccgagagccgcgcg tgcacctacttcgctttcgccatgaccttcttcagcctggccacgatgctcatgctcttcgccatggccctggagcgcta cctctcgatcgggcacccctacttctaccagcgccgcgtctcggcctccgggggcctggccgtgctgcctgtcatctatg cagtctccctgctcttctgctcgctgccgctgctggactatgggcagtacgtccagtactgccccgggacctggtgcttc atccggcacgggcggaccgcttacctgcagctgtacgccaccctgctgctgcttctcattgtctcggtgctcgcctgcaa cttcagtgtcattctcaacctcatccgcatgcaccgccgaagccggagaagccgctgcggaccttccctgggcagtggcc ggggcggccccggggcccgcaggagaggggaaagggtgtccatggcggaggagacggaccacctcattctcctggctatc atgaccatcaccttcgccgtctgctccttgcctttcacgatttttgcatatatgaatgaaacctcttcccgaaaggaaaa atgggacctccaagctcttaggtttttatcaattaattcaataattgacccttgggtctttgccatccttaggcctcctg ttctgagactaatgcgttcagtcctctgttgtcggatttcattaagaacacaagatgcaacacaaacttcctgttctaca cagtcagatgccagtaaacaggctgacctttgaggtcagtagtttaaaagttcttagttatatagcatctggaagatcat tttgaaattgttccctggagaaatgaaaacagtgtgtaaacaaaatgaagctgccctaataaaaaggagtatacaaacat ttaagctgtggtcaaggctacagatgtgctgacaaggcacttcatgtaaagtgtcagaaggagctacaaaacctaccctc aatgagcatggtacttggcctttggaggaacaatcggctgcattgaagatccagctgcctattgatttaagctttcctgt tgaatgacaaagtatgtggttttgtaatttgtttgaaaccccaaacagtgactgtactttctattttaatcttgctacta ccgttatacacatatagtgtacagccagaccagattaaacttcatatgtaatctctaggaagtcaatatgtggaagcaac caagcctgctgtcttgtgatcacttagcgaaccctttatttgaacaatgaagttgaaaatcataggcaccttttactgtg atgtttgtgtatgtgggagtactctcatcactacagtattactcttacaagagtggactcagtgggttaacatcagtttt gtttac catcctccaggaactgcaggtcaagttgtcaggttatttattttataatgtccatatgctaatagtgatcaag aagactttaggaatggttctctcaacaagaaataatagaaatgtctcaaggcagttaattctcattaatactcttattat cctatttctgggggaggatgtacgtggccatgtatgaagccaaatattaggcttaaaaactgaaaaatctggttcattct tcagatatactggaacccttttaaagttgatattggggccatgagtaaaatagattttataagatgactgtgttgtacca aaattcatctgtctatattttatttaggggaacatggtttgactcatcttatatgggaaaccatgtagcagtgagtcata tcttaatatatttctaaatgtttggcatgtaaatgtaaactcagcatcaaaatatttcagtgaatttgcactgtttaatc atagttactgtgtaaactcatctgaaatgttacaaaaataaactataaaacagggggcggcagggctgagcggccggtga tggggaccccacatcccaggcagtgccggcacccctggcgcctgacatgagcccttgcgggcccctcaacctgagcctgg cgggcgaggcgaccacatgcgcggcgccctgggtccccaacacgtcggccgtgccgccgtcgggcgcttcgcccgcgctg cccatcttctccatgacgctgggcgccgtgtccaacctgctggcgctggcgctgctggcgcaggccgcgggccgcctgcg acgccgccgctcggccaccaccttcctgctgttcgtggccagcctgctggccaccgacctggcgggccacgtgatcccgg gcgcgctggtgctgcgtctgtacactgcggggcgcgctccggccggcggggcctgccacttcctgggcggctgcatggtc ttcttcggcctgtgcccgctgctgctgggctgtggcatggccgtggagcgctgcgtgggcgtcacgcggccgctgctcca cgccgcgcgggtctcggtcgcccgcgcgcgcctggcgctggccgcggtggccgcggtggccttggccgtggcgctgctgc cgctggcgcgcgtgggccgctatgagctgcagtacccgggcacgtggtgcttcatcggcctgggtcccccgggcggctgg cgccaggcactgcttgctggcctcttcgccagcctcggcctggtcgcgctcctcgccgcgctggtgtgcaacacgctcag cggcctggccctgcatcgcgcccgctggcgacgccgctcccgacggcctcccccggcctcaggccccgacagccggcgtc gctggggggcgcacggaccccgctcggcctccgcctcgtccgcctcgtccatcgcttcggcctccaccttctttggcggc tctcggagcagcggctcggcacgcagagctcgcgcccacgacgtggagatggtgggccagcttgtcggtatcatggtggt gtcgtgcatctgctggagcccaatgctggtgttggtggcgctggccgtcggcggctggagctctacctccctgcagcggc cactgttcctggccgtgcgccttgcctcctggaaccagatcctggacccttgggtgtacatcctactgcgccaggccgtg ctgcgccaactgcttcgcctcttgcccccgagggccggagccaagggcggccccgcggggctgggcctaacaccgagcgc ctgggaggccagctcgctgcgcagctcccggcacagcggcctcagccacttctaagcacaaccagaggcccaacgactaa gccagcccaccctgggctgggcccaggtgcgcggcgcagagcctttgggaataaaaagccattctgcgatgggcaatgcc tccaatgactcccagtctgaggactgcgagacgcgacagtggcttcccccaggcgaaagcccagccatcagctccgtcat gttctcggccggggtgctggggaacctcatagcactggcgctgctggcgcgccgctggcggggggacgtggggtgcagcg ccggccgcaggagctccctctccttgttccacgtgctggtgaccgagctggtgttcaccgacctgctcgggacctgcctc atcagcccagtggtactggcttcgtacgcgcggaaccagaccctggtggcactggcgcccgagagccgcgcgtgcaccta cttcgctttcgccatgaccttcttcagcctggccacgatgctcatgctcttcgccatggccctggagcgctacctctcga tcgggcacccctacttctaccagcgccgcgtctcgcgctccgggggcctggccgtgctgcctgtcatctatgcagtctcc ctgctcttctgctcgctgccgctgctggactatgggcagtacgtccagtactgccccgggacctggtgcttcatccggca cgggcggaccgcttacctgcagctgtacgccaccctgctgctgcttctcattgtctcggtgctcgcctgcaacttcagtg tcattctcaacctcatccgcatgcaccgccgaagccggagaagccgctgcggaccttccctgggcagtggccggggcggc cccggggcccgcaggagaggggaaagggtgtccatggcggaggagacggaccacctcattctcctggctatcatgaccat caccttcgccgtctgctccttgcctttcacgatttttgcatatatgaatgaaacctcttcccgaaaggaaaaatgggacc tccaagctcttaggtttttatcaattaattcaataattgacccttgggtctttgccatccttaggcctcctgttctgaga ctaatgcgttcagtcctctgttgtcggatttcattaagaacacaagatgcaacacaaacttcctgttctacacagtcaga tgccagtaaacaggctgacctttgactgcagatgggaagaggtttttccaggaatttaaattgtgcaataaggccacaca atcttacttaaaaaaaatggtgaaggggttttaattacaccatgaagttttacaattttttaggtttttagttctggttt tagaaaacagagtagaaggattaacagagaaaaacttcaccattagacaagaagtcaaaatgattctaagggccgcgcaa acaggctttccaagaattaatcatgaggtggtgcttggagaattcctttactccagtgactttgaaacccccttctcact ctccactagtctttcaaaggattcatggtgaattgggtctaacgagtataacacggccggccgaacgatgaagctcacgc taccctttcagggcggagaagttcccaggaggaagaatggagaaaaagatcgcagttaggcagtcctcccaacctcacca aggctccacctctctccaaagccgcaacgtgctgccacctgcgccgggagaggctgcaatcactgtctcctcctctttct ttctctttttttttttttcttttttgcctggggtgcccgaccaagcgcagccgcagtctgggcactgccaactgactcca actccttttatggtgagaggatggattcttcgttatttccccgcccaatctggtacccacccacccacccacccaccacg tccgctgggcgcacccaagtctaaccccggggcgcacgccgtagcgcagacaccgtatttctcctcctttctcggccaac cctaggtagaatcctaaaacaactgccctctcttccacgatctagatgttgcggcccgcggacaggaggttcaagaaata gtacactccgagcggcaggcagcgagagcggaaacggtcgccggtttcagtggtggccccactggaagccgagttcagga gcggctaagcgtcgccggggaaagcaccggggcttcccagggtctcctccgagttcccactccgcacctccgagggcgtg aaaaccacgggagccgcccgccccgcgcgcccagccccgccccagcccagacaccgccccccgccagtcttccctgcggc gcccagggaggacgccgtccgcccccttccaatccggccaatgggcgcccgggcagcgcgcggtttgcctccgcctccgc cagggaaacttggaggaggagaaaagtttgtacagagggtggaaaggccgcagcacgcgagctccaagcccggcagcccg agaggaagatgaacagccccaggccagagcctctgcgagagtggaccccgagccgcccccaggtagccaggagcggcctc agcggcagccgcaaactccagtagccgcccgtgctgcccgtgctggggcggagggcagccagagctggggaccaaggctc cgcgccacctgggcacagcctcacacctgaacgctgtcctcccgcagacgagaccggcgggcactgcaaagctgggactc gtctttgaaggaaaaaaaatagcgagtaagaaatccagcaccattcttcactgacccatcccgctgcacctcttgtttcc caagtttttgaaagctggcaactctgacctcggtgtccaaaaatcgacagccactgagaccggctttgagaagccgaaga tttggcagtttccagactgagcaggacaaggtgaaagcaggttggaggcgggtccaggacatctgagggctgaccctggg ggctcgtgaggctgccaccgctgctgccgctacaggtgagatggcgttgggctgacgttggggtcaacgggtagagaacg agggatgccgccctcgccgaagagagccaagaggggaagagcgcgctctccaaattgcttttgtaacttgttttcagtga gcattttattgattcagaatctatcgagaatagcactagcgagctactttccccttgagatgggtcttattca cttggc aatggagtgagttggattgtggggaggaagaggaatgggaaaatcagtttataaatattaatgtcagccaagagtgtgct gttggcaggacgtatcgcgagcctggagattttggtggccgcagttggtaagtggctacaatccagaaagtaggatcgag ttgctccccttgtcttatcagtgtatcgtttctcgggcgcgggtctaacaccttacaagtggtaatttccgctcacggca gctttgtctctcttctaccatccccagacccagccttgcactccaaggctgcgcaccgccagccactatcatgtccactc ccggggtcaattcgtccgcctccttgagccccgaccggctgaacagcccagtaaccatcccggcggtgatgttcatcttc ggggtggtgggcaacctggtggccatcgtggtgctgtgcaagtcgcgcaaggagcagaaggagacgaccttctacacgct ggtatgtgggctggctgtcaccgacctgttgggcactttgttggtgagcccggtgaccatcgccacgtacatgaagggcc aatggcccgggggccagccgctgtgcgagtacagcaccttcattctgctcttcttcagcctgtccggcctcagcatcatc tgcgccatgagtgtcgagcgctacctggccatcaaccatgcctatttctacagccactacgtggacaagcgattggcggg cctcacgctctttgcagtctatgcgtccaacgtgctcttttgcgcgctgcccaacatgggtctcggtagctcgcggctgc agtacccagacacctggtgcttcatcgactggaccaccaacgtgacggcgcacgccgcctactcctacatgtacgcgggc ttcagctccttcctcattctcgccaccgtcctctgcaacgtgcttgtgtgcggcgcgctgctccgcatgcaccgccagtt catgcgccgcacctcgctgggcaccgagcagcaccacgcggccgcggccgcctcggttgcctcccggggccaccccgctg cctccccagccttgccgcgcctcagcgactttcggcgccgccggagcttccgccgcatcgcgggcgccgagatccagatg gtcatcttactcattgccacctccctggtggtgctcatctgctccatcccgctcgtggtgagtgaccgggggtggggccc tactcggcctttttctcgcatccacctcccgcgtccattccccgctccctgttttccctctgagtccttgggagtgaacg tgtcgcctttaggtcggggctgggattcccacactgtttctcagaggaggcccaacccctctttggaagtcccaacccta acgcgatttagcaggtgctttggccctacatcccccagtttatgtttcccggaaggctggagcccatgactggtttttct gaggcttattatgtagcttcctcttttcctggaacttgttaccagaaatgaaggcagcttcctaatattgataaggtaga catagcatttatatgttttcccaattgattaatgatgaaatctaaatgtgcgactcacttatgcaggtgcgagtattcgt caaccagttatatcagccaagtttggagcgagaagtcagtaaaaatccagatttgcaggccatccgaattgcttctgtga accccatcctagacccctggatatatatcctcctgagaaagacagtgctcagtaaagcaatagagaagatcaaatgcctc ttctgccgcattggcgggtcccgcagggagcgctccggacagcactgctcagacagtcaaaggacatcttctgccatgtc aggccactctcgctccttcatctcccgggagctgaaggagatcagcagtacatctcagaccctcctgccagacctctcac tgccagacctcagtgaaaatggccttggaggcaggaatttgcttccaggtgtgcctggcatgggcctggcccaggaagac accacctcactgaggactttgcgaatatcagagacctcagactcttcacagggtcaggactcagagagtgtgttactggt ggatgaggctggtggaagcggcagggcagggcctgcccctaaggggagctccctgcaagtcacatttcccagtgaaacac tgaacttatcagaaaaatgtatataataggcaaggaaagaaatacagtactgtttctggacccttataaaatcctgtgca atagacacatacatgtcaca (SEQ ID NO: 11983) aagcttcctgtacctggaatattaatattttatttcagatttgggaaattttcagctagcaatctttaaatatgctttct gacccccttttcctctattttctccttcttaaactactgtaatgtgaacattagctctcttttttaatttttaatttaat ttttgtttttattttttgagatgcagtctcactctgtcacccaggctggagtgcagtggcatgatctcagctcactgcaa cctttgccttctaggttgaagagattctgctgcctcagtctccccatgagctgggattacagcatgtgccacaatccctg gctaatttttttgtatttttagtagagactgggtttcaccatgttggtcaggctggtcttgactcctgacctcaggtgat ccactcaccttggcctcccaaagcgctgggattatggcatgagccactgagtctggctgaatgttagctctcttgatgct gtcccataaatcttgtaggctttcatcatttcttttcattcttttttctcctctcactgtatattttcaaaaacctgtct tcagttcacagattctttcttctgcttgatcaagtctgctactggtgatttctactgcatttctcacttcattcattata tttttcagctccaatttcttttatgatttcaatctttctgttacatttcttatgttgtgcatttattgtttctctgattt caccaaattgtttctctgtgtttgcttcaaagtaactgagcttctttaaaaacaattatcttgaatccattgtcaggcca tttgtagtactccatttcttttgggtcagctactgggaaattattgtgtttcttaggtggtgatattttaatttgggttt tcatgtttcttgctgccttacactgctgtctgagcatctggtggatctgccccaatttcaggctgtatgggctgactttg gtggagaaataccttcttatgtggaataatgcgaggatgctggctgggtgggatgcaaaagttctgacttcagtaggggc aaagctgtgtggtctccatgcagatctgtcagctgaggttggtgttagtgaatactacagggatccttagaggccaacac tgtgggtatctacagtggcaatgaggctgttgaggttttcaattgtgacaagtcctccatatctctttttttccccacct gggaagtcatgactgaggacatccctcttggaattaggtctaacttgcaggcctgctcctggtggtggtgacactggtgt ctgatgaacagtgcccatggagtggccaagagccaaggcctgaagcatgggcatgcatggagggaccacagcaccagatt caattgtagcaatggtaccagtgcccaaggcacaggcatacttactatcacattgataatggtgtgtaaaatgcaggtac ttataaagcagctaaggagccagggactttactgcatgcatacgcagagctacagtggctccaggatccagggtgtgggc tagctctccttggtggctgagctggtgactagagcatggacaggcacagagaaaccttgactctaggacccagggtgttc actagctcactatagtggtggctctggtgttggaggtgtgggtgtgtgtagtacagcctcagagacagggtctggagcgc aggtgtgcacattactacagcagctctggagttgagaatatgggttacctttctacagtggctgaactagtgtctggagc aaagactttcacagagagaacttggcttggggtcccagggtgagatctagttcacaacagcagtgactccagtgtctgag acatgaggaggtgcactgcagccacagagccacagtccagagtgtgaatatctgtagagcagccacaacttttggggatc aggaacacacatagaattgtgagaggtggtaaccctggccccagtcctggcgagtgcaacaatagctgcttcttggtgag ggggtgtgaggggtagtgcaactgtgtttccctttttagcatcctgctatgggaatggctgttggacaaaagatgccagt gtcctctgtggagcaggacactgggggcctcagtggctctgtgtcacatgactgacacagatagcctacaaatttcttta ttcgtagctatctcctggtgtctcatatatgccagtctcaccggtgattcttctacatgaatattctttcttttctccat tgtgttgttccaaattctttaacaggctcttgagccccatcccccaactccccacccttgtgagggctattttggtttgt gtataactgtctatgtttgtttttttgttggggcataaggctgacatctcctactccaccatcttgctaatgtcacctgc ataggaatctttttatgctttccttatattcactaaaatttaacaatatcaaacttaaaaacatatgatcaattgaactt attaatatcaaacttattataaataagaaactaccaggctgggcatggtggctcatgcctgtaatcccaacattttggga ggctgaggtgaaaggatcacttgagcccaggaattcaagaccagcctgggaaatatagagagaccctatctctagagatt tttttttttaattagccagtagtgatggcacacatctatagtcccagctactcaggaggctgaggtgggagaattgcttg agcccaggaggtcaaggctgcagcaagcagtaatcatgccactgcactccagcctgggccgcagagtgagaccctgtctc aaaaaaagaacctactagtctacataccacacttcttcatccccatctgagactatatatattttttctaacatgaggca atgccaaaaagaggagctggtgagtgaaagtaagaacagaaagacatggaggcaagtcttatagaataatagccaacact taaacttacacttaacagcgtgataggtattgttccaaacacattaaattcatttaatggtccttacatgtctatgtatt tggtgattattatccttattattcacattgctgagtgtattattctgttctcatgatgctgatagagacatacccgagac tggataacttattaaaaaaaaaaaggtttaatggactcacagttccacgtggatggggagtcctcacaatcatggtagaa agcaaaagacacgtcttacatggcagcagggaagagagagaaatgagaaccaaacaaaaggggtttccccttataaaacc atcagctctcatgcgacttattcactaccatgagaacagtatgggggaaaccacccccatgattcaatgatctaccaggt gcctcccacaacctgtgggaattatgggagctacaattccagatgagatttgggtggggacacagccaaaccacatcact gaggaaactgagtt tagggagattagtaacgcccaacacagctggtaggtggtggagccaggcagtctgactctagggt ctggactctgaactgcatcatgctgccaagaagttcctcattttttcctctctctaagtttcccttattcccctacagtc attccttcaacagcatttccttcaccatcttttctacttctactatataattaattttttcttcttggtcccaaattcca acgtgcaaatgcagccttatataccctaattcatctttacctttagactttcttccaatgtttctacttcattccatttt aaatttatccatgagatgcctatttacaagctgtaaccatcatgaagtgaatgaagaataatacctactactgtacaata gaattccaagagtataaataggagttatggctttctgacttgaaactaaatacttgatacttgattttgctgtctgagat caatctgaaaagtaataataatcactaacatttgttgagcatcaattgtgggccaagtgtcatttcaatcactctgtaca tattaactcatttcatcctacaacaacccggtgaggcaagttctgttattctgttttacagttgaggaaacagaggcata gagagcttaagtagtttgcccagtagatagccagaagaggagccaggatgggtctcgggcagtttaacagcacagctgaa gtcttaaccactatgccaacagctttttggtcctacacatcccatgggaagaggaaaataaaaaggtatctatttgtata cctttttatttctgatataagaagcagaattcctttcacatgacctatgtctatttaatacgtcattttgaaacttacca ataaaatttcccaagcgccagaaaactgttagtggctttttccattcttctctatttttttttgtgctactaattttgct tctttccctcagaaggctgccggaatagtaaacattcactgacatgtcataattactggaaaatgggcactggaaaatca cattgtaattaattcaaagcatgttttccaaatgtactactttaaattggagcttatatcataatccaaggaaacctttg tgtgtgtactgttcccacattgctcagcctgggatatccaggagtaattcaccttgcgcctgcctccagaccatcttcca tggaagggggtgaccccttgcctcttggcaaccactatttctaagctgccaacattactcttgcattatcaacattctaa cttcatgggaagggctgtggtgagtttctggaatgtgaataggaagttgtttttctaaacagcctgacactgaggggagg cagtgagactgtaagcagtctgggttgggcagaaggcagaaaaccagcagagtcacagaggagatg (SEQ ID NO: 11984) gtcgaggatccctaaagtcctttgaagctttcatattctgtaacttttgtgccaagaaggccttacagtgagatgggatc ccagtatttattgagtttcctcattcataaaatggggataataatagtaaatgagttgacacgcgctaagacagtggaat agtggctggcacagataagccctcggtaaatggtagccaataatgatagagtatgctgtaagatatctttctctccctct gcttctcaacaagtctctaatcaattattccactttataaacaaggaaatagaactcaaagacattaagcacttttccaa aggtcgcttagcaagtaaatgggagagaccctatgaccaggatgaaagcaagaaattcccacaagaggactcattccaac tcatatcttgtgaaaaggttcccaatgcccagctcagatcaactgcctcaatttacagtgtgagtgtgctcacctccttt ggggactgtatatccagaggaccctcctcaataaaacactttataaataacatccttccatggatgagggaaaggaggta agatctgtaatgaataagcaggaactttgaagactcagtgactcagtgagtaataaagactcagtgacttctgatcctgt cctaactgccactccttgttgtcccaagaaagcggcttcctgctctctgaggaggaccccttccctggaaggtaaaacta aggatgtcagcagagaaatttttccaccattggtgcttggtcaaagaggaaactgatgagctcactctagatgagagagc agtgagggagagacagagactcgaatttccggagctatttcagttttcttttccgttttgtgcaatttcacttatgatac cggccaatgcttggttgctattttggaaactccccttaggggatgcccctcaactggccctataaagggccagcctgagc tgcagaggatcaagacagcacgtggacctcgcacagcctctcccacaggtaccatg (SEQ ID NO: 11985) cctccgacagcctctccacaggtaccatgaaggtctccgcggcacgcctcgctgtcatcctcattgctactgccctctgc gctcctgcatctgcctccccatat cctcggacaccacaccctgctgctttgcctacattgcccgcccactgccccgtgc ccacatcaaggagtatttctacaccagtggcaagtgctccaacccagcagtcgtctttgtcacccgaaagaaccgccaag tgtgtgccaacccagagaagaaatgggttcgggagtacatcaactctttggagatgagctaggatggagagtccttgaac ctgaacttacacaaatttgcctgtttctgcttgctcttgtcctagcttgggaggcttcccctcactatcctaccccaccc gc ccttgaagggcccagattctgaccacgacgagcagcagttacaaaaaccttccccaggctggacgtggtggctcagc cttgtaatcccagcactttgggaggccaaggtgggtggatcacttgaggtcaggagttcgagacagcctggccaacatga tgaaaccccatgtgtactaaaaatacaaaaaattagccgggcgtggtagcgggcgcctgtagtcccagctactcgggagg ctgaggcaggagaatggcgtgaacccgggagcggagcttgcagtgagccgagatcgcgccactgcactccagcctgggcg acagagcgagactccgtctcaaaaaaaaaaaaaaaaaaaaaaaaaatacaaaaattagccgcgtggtggcccacgcctgt aatcccagctactcgggaggctaaggcaggaaaattgtttgaacccaggaggtggaggctgcagtgagctgagattgtgc cacttcactccagcctgggtgacaaagtgagactccgtcacaacaacaacaacaaaaagcttccccaactaaagcctaga agagcttctgaggcgctgctttgtcaaaaggaagtctctaggttctgagctctggctttgccttggctttgcaagggctc tgtgacaaggaaggaagtcagcatgcctctagaggcaaggaagggaggaacactgcactcttaagcttccgccgtctcaa cccctcacaggagcttactggcaaacatgaaaaatcgggg (SEQ ID NO: 11986) gtcgaggatccctaaagtcctttgaagctttcatattctgtaacttttgtgccaagaaggccttacagtgagatgggatc ccagtatttattgagtttcctcattcataaaatggggataataatagtaaatgagttgacacgcgctaagacagtggaat agtggctggcacagataagccctcggtaaatggtagccaataatgatagagtatgctgtaagatatctttctctccctct gcttctcaacaagtctctaatcaattattccactttataaacaaggaaatagaactcaaagacattaagcacttttccaa aggtcgcttagcaagtaaatgggagagaccctatgaccaggatgaaagcaagaaattcccacaagaggactcattccaac tcatatcttgtgaaaaggttcccaatgcccagctcagatcaactgcctcaatttacagtgtgagtgtgctcacctccttt ggggactgtatatccagaggaccctcctcaataaaacactttataaataacatccttccatggatgagggaaaggaggta agatctgtaatgaataagcaggaactttgaagactcagtgactcagtgagtaataaagactcagtgacttctgatcctgt cctaactgccactccttgttgtcccaagaaagcggcttcctgctctctgaggaggaccccttccctggaaggtaaaacta aggatgtcagcagagaaatttttccaccattggtgcttggtcaaagaggaaactgatgagctcactctagatgagagagc agtgagggagagacagagactcgaatttccggagctatttcagttttcttttccgttttgtgcaatttcacttatgatac cggccaatgcttggttgctattttggaaactccccttaggggatgcccctcaactggccctataaagggccagcctgagc tgcagaggatcaagacagcacgtggacctcgcacagcctctcccacaggtaccatgcctccgacagcctctccacaggta ccatgaaggtctccgcggcacgcctcgctgtcatcctcattgctactgccctctgcgctcctgcatctgcctccccatat tcctcggacaccacaccctgctgctttgcctacattgcccgcccactgccccgtgcccacatcaaggagtatttctacac cagtggcaagtgctccaacccagcagtcgtctttgtcacccgaaagaaccgccaagtgtgtgccaacccagagaagaaat gggttcgggagtacatcaactctttggagatgagctaggatggagagtccttgaacctgaacttacacaaatttgcctgt ttctgcttgctcttgtcctagcttgggaggcttcccctcactatcctaccccacccgctccttgaagggcccagattctg accacgacgagcagcagttacaaaaaccttccccaggctggacgtggtggctcagccttgtaatcccagcactttgggag gccaaggtgggtggatcacttgaggtcaggagttcgagacagcctggccaacatgatgaaaccccatgtgtactaaaaat acaaaaaattagccgggcgtggtagcgggcgcctgtagtcccagctactcgggaggctgaggcaggagaatggcgtgaac ccgggagcggagcttgcagtgagccgagatcgcgccactgcactccagcctgggcgacagagcgagactccgtctcaaaa aaaaaaaaaaaaaaaaaaaaaatacaaaaattagccgcgtggtggcccacgcctgtaatcccagctactcgggaggctaa ggcaggaaaattgtttgaacccaggaggtggaggctgcagtgagctgagattgtgccacttcactccagcctgggtgaca aagtgagactccgtcacaacaacaacaacaaaaagcttccccaactaaagcctagaagagcttctgaggcgctgctttgt caaaaggaagtctctaggttctgagctctggctttgccttggctttgcaagggctctgtgacaaggaaggaagtcagcat gcctctagaggcaaggaagggaggaacactgcactcttaagcttccgccgtctcaacccctcacaggagcttactggcaa acatgaaaaatcgggg (SEQ ID NO: 11987) at aaacctctcgccgagcccctccgcagactctgcgccggaaagtttcatttgctgtatgccatcctcgagagctgtct aggttaacgttcgcactctgtgtatataacctcgacagtcttggcacctaacgtgctgtgcgtagctgctcctttggttg aatccccaggcccttgttggggcacaaggtggcaggatgtctcagtggtacgaacttcagcagcttgactcaaaattcct ggagcaggttcaccagctttatgatgacagttttcccatggaaatcagacagtacctggcacagtggttagaaaagcaag actgggagcacgctgccaatgatgtttcatttgccaccatccgttttcatgacctcctgtcacagctggatgatcaatat agtcgcttttctttggagaataacttcttgctacagcataacataaggaaaagcaagcgtaatcttcaggataattttca ggaagacccaatccagatgtctatgatcatttacagctgtctgaaggaagaaaggaaaattctggaaaacgcccagagat ttaatcaggctcagtcggggaatattcagagcacagtgatgttagacaaacagaaagagcttgacagtaaagtcagaaat gtgaaggacaaggttatgtgtatagagcatgaaatcaagagcctggaagatttacaagatgaatatgacttcaaatgcaa aaccttgcagaacagagaacacgagaccaatggtgtggcaaagagtgatcagaaacaagaacagctgttactcaagaaga tgtatttaatgcttgacaataagagaaaggaagtagttcacaaaataatagagttgctgaatgtcactgaacttacccag aatgccctgattaatgatgaactagtggagtggaagcggagacagcagagcgcctgtattggggggccgcccaatgcttg cttggatcagctgcagaactggttcactatagttgcggagagtctgcagcaagttcggcagcagcttaaaaagttggagg aattggaacagaaatacacctacgaacatgaccctatcacaaaaaacaaacaagtgttatgggaccgcaccttcagtctt ttccagcagctcattcagagctcgtttgtggtggaaagacagccctgcatgccaacgcaccctcagaggccgctggtctt gaagacaggggtccagttcactgtgaagttgagactgttggtgaaattgcaagagctgaattataatttgaaagtcaaag tcttatttgataaagatgtgaatgagagaaatacagtaaaaggatttaggaagttcaacattttgggcacgcacacaaaa gtgatgaacatggaggagtccaccaatggcagtctggcggctgaatttcggcacctgcaattgaaagaacagaaaaatgc tggcaccagaacgaatgagggtcctctcatcgttactgaagagcttcactcccttagttttgaaacccaattgtgccagc ctggtttggtaattgacctcgagacgacctctctgcccgttgtggtgatctccaacgtcagccagctcccgagcggttgg gcctccatcctttggtacaacatgctggtggcggaacccaggaatctgtccttcttcctgactccaccatgtgcacgatg ggctcagctttcagaagtgctgagttggcagttttcttctgtcaccaaaagaggtctcaatgtggaccagctgaacatgt tgggagagaagcttcttggtcctaacgccagccccgatggtctcattccgtggacgaggttttgtaaggaaaatataaat gataaaaattttcccttctggctttggattgaaagcatcctagaactcattaaaaaacacctgctccctctctggaatga tgggtgcatcatgggcttcatcagcaaggagcgagagcgtgccctgttgaaggaccagcagccggggaccttcctgctgc ggttcagtgagagctcccgggaaggggccatcacattcacatgggtggagcggtcccagaacggaggcgaacctgacttc catgcggttgaaccctacacgaagaaagaactttctgctgttactttccctgacatcattcgcaattacaaagtcatggc tgctgagaatattcctgagaatcccctgaagtatctgtatccaaatattgacaaagaccatgcctttggaaagtattact ccaggccaaaggaagcaccagagccaatggaacttgatggccctaaaggaactggatatatcaagactgagttgatttct gtgtctgaagttcacccttctagacttcagaccacagacaacctgctccccatgtctcctgaggagtttgacgaggtgtc tcggatagtgggctctgtagaattcgacagtatgatgaacacagtatagagcatgaatttttttcatcttctctggcgac agttttccttctcatctgtgattccctcctgctactctgttccttcacatcctgtgtttctagggaaatgaaagaaaggc cagcaaattcgctgcaacctgttgatagcaagtgaatttttctctaactcagaaacatcagttactctgaagggcatcat gcatcttactgaaggtaaaattgaaaggcattctctgaagagtgggtttcacaagtgaaaaacatccagatacacccaaa gtatcaggacgagaatgagggtcctttgggaaaggagaagttaagcaacatctagcaaatgttatgcataaagtcagtgc ccaactgttataggttgttggataaatcagtggttatttagggaactgcttgacgtaggaacggtaaatttctgtgggag aattcttacatgttttctttgctttaagtgtaactggcagttttccattggtttacctgtgaaatagttcaaagccaagt ttatatacaattatatcagtcctctttcaaaggtagccatcatggatctggtagggggaaaatgtgtattttattacatc tttcacattggctatttaaagacaaagacaaattctgtttcttgagaagagaatattagctttactgtttgttatggctt aatgacactagctaatatcaatagaaggatgtacatttccaaattcacaagttgtgtttgatatccaaagctgaatacat tctgctttcatcttggtcacatacaattatttttacagttctcccaagggagttaggctattcacaaccactcattcaaa agttgaaattaaccatagatgtagataaactcagaaatttaattcatgtttcttaaatgggctactttgtcctttttgtt attagggtggtatttagtctattagccacaaaattgggaaaggagtagaaaaagcagtaactgacaacttgaataataca ccagagataatatgagaatcagatcatttcaaaactcatttcctatgtaactgcattgagaactgcatatgtttcgctga tatatgtgtttttcacatttgcgaatggttccattctctctcctgtactttttccagacacttttttgagtggatgatgt ttcgtgaagtatactgtatttttacctttttccttccttatcactgacacaaaaagtagattaagagatgggtttgacaa ggttcttcccttttacatactgctgtctatgtggctgtatcttgtttttccactactgctaccacaactatattatcatg caaatgctgtattcttctttggtggagataaagatttcttgagttttgttttaaaattaaagctaaagtatctgtattgc attaaatataatatcgacacagtgctttccgtggcactgcatacaatctgaggcctcctctctcagtttttatatagatg gcgagaacctaagtttcagttgattttacaattgaaatgactaaaaaacaaagaagacaacattaaaaacaatattgttt Cta (SEQ ID NO: 11988) attaaacctctcgccgagcccctccgcagactctgcgccggaaagtttcatttgctgtatgccatcctcgagagctgtct aggttaacgttcgcactctgtgtatataacctcgacagtcttggcacctaacgtgctgtgcgtagctgctcctttggttg aatccccaggcccttgttggggcacaaggtggcaggatgtctcagtggtacgaacttcagcagcttgactcaaaattcct ggagcaggttcaccagctttatgatgacagttttcccatggaaatcagacagtacctggcacagtggttagaaaagcaag actgggagcacgctgccaatgatgtttcatttgccaccatccgttttcatgacctcctgtcacagctggatgatcaatat agtcgcttttctttggagaataacttcttgctacagcataacataaggaaaagcaagcgtaatcttcaggataattttca ggaagacccaatccagatgtctatgatcatttacagctgtctgaaggaagaaaggaaaattctggaaaacgcccagagat ttaatcaggctcagtcggggaatattcagagcacagtgatgttagacaaacagaaagagcttgacagtaaagtcagaaat gtgaaggacaaggttatgtgtatagagcatgaaatcaagagcctggaagatttacaagatgaatatgacttcaaatgcaa aaccttgcagaacagagaacacgagaccaatggtgtggcaaagagtgatcagaaacaagaacagctgttactcaagaaga tgtatttaatgcttgacaataagagaaaggaagtagttcacaaaataatagagttgctgaatgtcactgaacttacccag aatgccctgattaatgatgaactagtggagtggaagcggagacagcagagcgcctgtattggggggccgcccaatgcttg cttggatcagctgcagaactggttcactatagttgcggagagtctgcagcaagttcggcagcagcttaaaaagttggagg aattggaacagaaatacacctacgaacatgaccctatcacaaaaaacaaacaagtgttatgggaccgcaccttcagtctt ttccagcagctcattcagagctcgtttgtggtggaaagacagccctgcatgccaacgcaccctcagaggccgctggtctt gaagacaggggtccagttcactgtgaagttgagactgttggtgaaattgcaagagctgaattataatttgaaagtcaaag tcttatttgataaagatgtgaatgagagaaatacagtaaaaggatttaggaagttcaacattttgggcacgcacacaaaa gtgatgaacatggaggagtccaccaatggcagtctggcggctgaatttcggcacctgcaattgaaagaacagaaaaatgc tggcaccagaacgaatgagggtcctctcatcgttactgaagagcttcactcccttagttttgaaacccaattgtgccagc ctggtttggtaattgacctcgagacgacctctctgcccgttgtggtgatctccaacgtcagccagctcccgagcggttgg gcctccatcctttggtacaacatgctggtggcggaacccaggaatctgtccttcttcctgactccaccatgtgcacgatg ggctcagctttcagaagtgctgagttggcagttttcttctgtcaccaaaagaggtctcaatgtggaccagctgaacatgt tgggagagaagcttcttggtcctaacgccagccccgatggtctcattccgtggacgaggttttgtaaggaaaatataaat gataaaaattttcccttctggctttggattgaaagcatcctagaactcattaaaaaacacctgctccctctctggaatga tgggtgcatcatgggcttcatcagcaaggagcgagagcgtgccctgttgaaggaccagcagccggggaccttcctgctgc ggttcagtgagagctcccgggaaggggccatcacattcacatgggtggagcggtcccagaacggaggcgaacctgacttc catgcggttgaaccctacacgaagaaagaactttctgctgttactttccctgacatcattcgcaattacaaagtcatggc tgctgagaatattcctgagaatcccctgaagtatctgtatccaaatat gacaaagaccatgcctttggaaagtattact ccaggccaaaggaagcaccagagccaatggaacttgatggccctaaaggaactggatatatcaagactgagttgatttct gtgtctgaagtgtaagtgaacacagaagagtgacatgtttacaaacctcaagccagccttgctcctggctggggcctgtt gaagatgcttgtattttacttttccattgtaattgctatcgccatcacagctgaacttgttgagatccccgtgttactgc ctatcagcattttactactttaaaaaaaaaaaaaaaagccaaaaaccaaatttgtatttaaggtatataaattttcccaa aactgataccctttgaaaaagtataaataaaatgagcaaaagttgaa (SEQ ID NO: 11989) ttactaagatgattattgttttatagcaattgaaagaacagaaaaatgctggcaccagaacgaatgaggtgagagtggtt tatgttgtgaatgggcc (SEQ ID NO: 11990) acgacctctctgcccgttgtggtgatctccaacgtcagccagctcccgagcggttgggcctccatcctttggtacaacat gctggtggtggcggaacccagggtatggaaaacacatttgctttggtcccagggtttaagcagagaccccacgctctcgc tgctgcatctcgctgctgcatctctgaaatagccccaat (SEQ ID NO: 11991) ggtctcaatgtggaccagctgaacatgttgggagagaagcttcttggtatatgcatattaacttgttatgtttataaaaa ttgaaattcataaaaatatc (SEQ ID NO: 11992) ctgatcagtagaaaacatgtttacatctttgtttgtagtgtatagagcatgaaatcaagagcctggaagatttacaagat gaatatgacttcaaatgcaaaaccttgcagaacagaggtaagggttcacaactgaagtggtgcccgttgg (SEQ ID NO:1199₃) attaaacctctcgccgagcccctccgcagactctgcgccggaaagtttcatttgctgtatgccatcctcgagagctgtct aggttaacgttcgcactctgtgtatataacctcgacagtcttggcacctaacgtgctgtgcgtagctgctcctttggttg aatccccaggcccttgttggggcacaaggtggcaggatgtctcagtggtacgaacttcagcagcttgactcaaaattcct ggagcaggttcaccagctttatgatgacagttttcccatggaaatcagacagtacctggcacagtggttagaaaagcaag actgggagcacgctgccaatgatgtttcatttgccaccatccgttttcatgacctcctgtcacagctggatgatcaatat agtcgcttttctttggagaataacttcttgctacagcataacataaggaaaagcaagcgtaatcttcaggataattttca ggaagacccaatccagatgtctatgatcatttacagctgtctgaaggaagaaaggaaaattctggaaaacgcccagagat ttaatcaggctcagtcggggaatattcagagcacagtgatgttagacaaacagaaagagcttgacagtaaagtcagaaat gtgaaggacaaggttatgtgtatagagcatgaaatcaagagcctggaagatttacaagatgaatatgacttcaaatgcaa aaccttgcagaacagagaacacgagaccaatggtgtggcaaagagtgatcagaaacaagaacagctgttactcaagaaga tgtatttaatgcttgacaataagagaaaggaagtagttcacaaaataatagagttgctgaatgtcactgaacttacccag aatgccctgattaatgatgaactagtggagtggaagcggagacagcagagcgcctgtattggggggccgcccaatgcttg cttggatcagctgcagaactggttcactatagttgcggagagtctgcagcaagttcggcagcagcttaaaaagttggagg aattggaacagaaatacacctacgaacatgaccctatcacaaaaaacaaacaagtgttatgggaccgcaccttcagtctt ttccagcagctcattcagagctcgtttgtggtggaaagacagccctgcatgccaacgcaccctcagaggccgctggtctt gaagacaggggtccagttcactgtgaagttgagactgttggtgaaattgcaagagctgaattataatttgaaagtcaaag tcttatttgataaagatgtgaatgagagaaatacagtaaaaggatttaggaagttcaacattttgggcacgcacacaaaa gtgatgaacatggaggagtccaccaatggcagtctggcggctgaatttcggcacctgcaattgaaagaacagaaaaatgc tggcaccagaacgaatgagggtcctctcatcgttactgaagagcttcactcccttagttttgaaacccaattgtgccagc ctggtttggtaattgacctcgagacgacctctctgcccgttgtggtgatctccaacgtcagccagctcccgagcggttgg gcctccatcctttggtacaacatgctggtggcggaacccaggaatctgtccttcttcctgactccaccatgtgcacgatg ggctcagctttcagaagtgctgagttggcagttttcttctgtcaccaaaagaggtctcaatgtggaccagctgaacatgt tgggagagaagcttcttggtcctaacgccagccccgatggtctcattccgtggacgaggttttgtaaggaaaatataaat ga aaaaattttcccttctggctttggattgaaagcatcctagaactcattaaaaaacacctgctccctctctggaatga tgggtgcatcatgggcttcatcagcaaggagcgagagcgtgccctgttgaaggaccagcagccggggaccttcctgctgc ggttcagtgagagctcccgggaaggggccatcacattcacatgggtggagcggtcccagaacggaggcgaacctgacttc catgcggttgaaccctacacgaagaaagaactttctgctgttactttccctgacatcattcgcaattacaaagtcatggc tgctgagaatattcctgagaatcccctgaagtatctgtatccaaatattgacaaagaccatgcctttggaaagtattact ccaggccaaaggaagcaccagagccaatggaacttgatggccctaaaggaactggatatatcaagactgagttgat tct gtgtctgaagttcacccttctagacttcagaccacagacaacctgctccccatgtctcctgaggagtttgacgaggtgtc tcggatagtgggctctgtagaattcgacagtatgatgaacacagtatagagcatgaatttttttcatcttctctggcgac agttttccttctcatctgtgattccctcctgctactctgttccttcacatcctgtgtttctagggaaatgaaagaaaggc cagcaaattcgctgcaacctgttgatagcaagtgaatttttctctaactcagaaacatcagttactctgaagggcatcat gcatcttactgaaggtaaaattgaaaggcattctctgaagagtgggtttcacaagtgaaaaacatccagatacacccaaa gtatcaggacgagaatgagggtcctttgggaaaggagaagttaagcaacatctagcaaatgttatgcataaagtcagtgc ccaactgttataggttgttggataaatcagtggttatttagggaactgcttgacgtaggaacggtaaatttctgtgggag aattcttacatgttttctttgctttaagtgtaactggcagttttccattggtttacctgtgaaatagttcaaagccaagt ttatatacaattatatcagtcctctttcaaaggtagccatcatggatctggtagggggaaaatgtgtattttattacatc tttcacattggctatttaaagacaaagacaaattctgtttcttgagaagagaatattagctttactgtttgttatggctt aatgacactagctaatatcaatagaaggatgtacatttccaaattcacaagttgtgtttgatatccaaagctgaatacat tctgctttcatcttggtcacatacaattatttttacagttctcccaagggagttaggctattcacaaccactcattcaaa agttgaaattaaccatagatgtagataaactcagaaatttaattcatgtttcttaaatgggctactttgtcctttttgtt attagggtggtatttagtctattagccacaaaattgggaaaggagtagaaaaagcagtaactgacaacttgaataataca ccagagataatatgagaatcagatcatttcaaaactcatttcctatgtaactgcattgagaactgcatatgtttcgctga tatatgtgtttttcacatttgcgaatggttccattctctctcctgtactttttccagacacttttttgagtggatgatgt ttcgtgaagtatactgtatttttacctttttccttccttatcactgacacaaaaagtagattaagagatgggtttgacaa ggttcttcccttttacatactgctgtctatgtggctgtatcttgtttttccactactgctaccacaactatattatcatg caaatgctgtattcttctttggtggagataaagatttcttgagttttgttttaaaattaaagctaaagtatctgtattgc attaaatataatatcgacacagtgctttccgtggcactgcatacaatctgaggcctcctctctcagtttttatatagatg gcgagaacctaagtttcagttgattttacaattgaaatgactaaaaaacaaagaagacaacattaaaaacaatattgttt ctaattaaacctctcgccgagcccctccgcagactctgcgccggaaagtttcatttgctgtatgccatcctcgagagctg tctaggttaacgttcgcactctgtgtatataacctcgacagtcttggcacctaacgtgctgtgcgtagctgctcctttgg ttgaatccccaggcccttgttggggcacaaggtggcaggatgtctcagtggtacgaacttcagcagcttgactcaaaatt cctggagcaggttcaccagctttatgatgacagttttcccatggaaatcagacagtacctggcacagtggttagaaaagc aagactgggagcacgctgccaatgatgtttcatttgccaccatccgttttcatgacctcctgtcacagctggatgatcaa tatagtcgcttttctttggagaataacttcttgctacagcataacataaggaaaagcaagcgtaatcttcaggataattt tcaggaagacccaatccagatgtctatgatcatttacagctgtctgaaggaagaaaggaaaattctggaaaacgcccaga gatttaatcaggctcagtcggggaatattcagagcacagtgatgttagacaaacagaaagagcttgacagtaaagtcaga aatgtgaaggacaaggttatgtgtatagagcatgaaatcaagagcctggaagatttacaagatgaatatgacttcaaatg caaaaccttgcagaacagagaacacgagaccaatggtgtggcaaagagtgatcagaaacaagaacagctgttactcaaga agatgtatttaatgcttgacaataagagaaaggaagtagttcacaaaataatagagttgctgaatgtcactgaacttacc cagaatgccctgattaatgatgaactagtggagtggaagcggagacagcagagcgcctgtattggggggccgcccaatgc ttgcttggatcagctgcagaactggttcactatagttgcggagagtctgcagcaagttcggcagcagcttaaaaagttgg aggaattggaacagaaatacacctacgaacatgaccctatcacaaaaaacaaacaagtgttatgggaccgcaccttcagt cttttccagcagctcattcagagctcgtttgtggtggaaagacagccctgcatgccaacgcaccctcagaggccgctggt cttgaagacaggggtccagttcactgtgaagttgagactgttggtgaaattgcaagagctgaattataatttgaaagtca aagtcttatttgataaagatgtgaatgagagaaatacagtaaaaggatttaggaagttcaacattttgggcacgcacaca aaagtgatgaacatggaggagtccaccaatggcagtctggcggctgaatttcggcacctgcaattgaaagaacagaaaaa tgctggcaccagaacgaatgagggtcctctcatcgttactgaagagcttcactcccttagttttgaaacccaattgtgcc agcctggtttggtaattgacctcgagacgacctctctgcccgttgtggtgatctccaacgtcagccagctcccgagcggt tgggcctccatcctttggtacaacatgctggtggcggaacccaggaatctgtccttcttcctgactccaccatgtgcacg atgggctcagctttcagaagtgctgagttggcagttttcttctgtcaccaaaagaggtctcaatgtggaccagctgaaca tgttgggagagaagcttcttggtcctaacgccagccccgatggtctcattccgtggacgaggttttgtaaggaaaatata aatgataaaaattttcccttctggctttggattgaaagcatcctagaactcattaaaaaacacctgctccctctctggaa tgatgggtgcatcatgggcttcatcagcaaggagcgagagcgtgccctgttgaaggaccagcagccggggaccttcctgc tgcggttcagtgagagctcccgggaaggggccatcacattcacatgggtggagcggtcccagaacggaggcgaacctgac ttccatgcggttgaaccctacacgaagaaagaactttctgctgttactttccctgacatcattcgcaattacaaagtcat ggctgctgagaatattcctgagaatcccctgaagtatctgtatccaaatattgacaaagaccatgcctttggaaagtatt actccaggccaaaggaagcaccagagccaatggaacttgatggccctaaaggaactggatatatcaagactgagttgatt tctgtgtctgaagtgtaagtgaacacagaagagtgacatgtttacaaacctcaagccagccttgctcctggctggggcct gttgaagatgcttgtattttacttttccattgtaattgctatcgccatcacagctgaacttgttgagatccccgtgttac tgcctatcagcattttactactttaaaaaaaaaaaaaaaagccaaaaaccaaatttgtatttaaggtatataaattttcc caaaactgataccctttgaaaaagtataaataaaatgagcaaaagttgaattactaagatgattattgttttatagcaat tgaaagaacagaaaaatgctggcaccagaacgaatgaggtgagagtggtttatgttgtgaatgggccacgacctctctgc ccgttgtggtgatctccaacgtcagccagctcccgagcggttgggcctccatcctttggtacaacatgctggtggtggcg gaacccagggtatggaaaacacatttgctttggtcccagggtttaagcagagaccccacgctctcgctgctgcatctcgc tgctgcatctctgaaatagccccaatggtctcaatgtggaccagctgaacatgttgggagagaagcttcttggtatatgc atattaacttgttatgtttataaaaattgaaattcataaaaatatcctgatcagtagaaaacatgtttacatctttgttt gtagtgtatagagcatgaaatcaagagcctggaagatttacaagatgaatatgacttcaaatgcaaaaccttgcagaaca gaggtaagggttcacaactgaagtggtgcccgttgg (SEQ ID NO: 11994) tcaagatcagcctgggcaacatggcgaaaccccgtctctacaataaatacaaaaaaattatcctggcggagttatgcacg ttgtagtcccaactacctgggaggctgaggcgggagaatcacctgagcctgggaggtcgaggctgcagcgagccgagatc ggccgctgcattccagcctgggtgacagagcgagaccatgtctcaaaaaataaaaattaaaaaaaaattgttttcattac ctcagccctcctcttcctatcccaaggcgtcgaaattccggtcccaccccttcccatggagcccttggcgtctccaggct cctcaagctagtttcggttccgggctcacgcgcgggttctcgaaaatcagctgtttcagtcttgggctagtccactaatt ggactcctcccctcgtagaaagtgcctacttgaacttctccaccaatcgctgaagctgcaggtgtggtttcggctcagct tgtcccgccctggcggaggggcggagttgcggcggcgccagtgagctcgcagtctgggaagggcttgactgaatggcagc cagtgtcggggtggcggctgggaatgggggccgctccggacttccgctgccaactacaagggggcgggtccgaggggggt tagccgaagttgtaggcggggcgcgaggttctagtacccgagctcatactagggacgggaagtcgcgaccagagccattg gagggcgcggggactgcaaccctaatcaggtacgggccctgagagggtgtgctggggtaggggtgggggtgagagtgaga gttcctccgagggaagggcgactggcccaggggttaccccctggagagggtagcttccttccccagattgaaataggagc tgtcgcctgctcggtcctcgatcttcttctgtccagcctatctccctaaccctaatgcccctctcccaaaactgccctgc agcttccgagacccggaatctggcattgttatgttggttcggtatctgacgtttttccctctgctctgcattatttttta tcttcaccaaaaaacgatgttcaaagatagataaatctaaaaacaaagatagataaatctattacccttgtttcgtaaaa agtataagctactgaaagatgaaacgattgcctaaggtcacacacaaaattcagttcatttcagaaaagcttcttgagtg caaaatatgtgcctaagaatgagagataatgagaaaaaattgtttcagccccttaacctcagtgtttgcaatccatttgg ggagaccaggttttttgtttttgttttcatatttgaatctttgctgacttgctcctttaatatcagacacttaaatcctc agatgggactcatcatattttttttgagatggaatcttcactatgttgctcaagcttggtctgcaactcctggctcaagc ca cctctcgtcttgttgggcctctcgtcttgtgggcctgcacaaagtgctgggattacaggcatgagccattcatgccc tgggcgcaccttggattgcgatgtgtgtgtgttgtgaagcttttttttttggtatcataaaagcaatacagatacatagt tttaaaaatcaagcagctactaaaagagttaaaatgaaaatagcccctcccaatccctcccttgttcctgctggaggtag aaaggcagctgatgttattcatgttagtagaagactctcccaccccaagcatttctctttattttgtaataaaatcatgt gacctttttagaccacaaatatgcatgaattctgttctgttaggctcaggctgcaacaagataagtttcagtttcctaaa tagacaccagctggcagtgagcagggaacagtggggagaaagatgcatgggacagcctgcttggtgacaggcaaaaaccg gtttgttgttcttttagagacagagtcttgctttgtcacccaggctggagtgtagtgatgtgatctctgcttactgcaac cctgcctctgggtacaagccattctcctgcctcagcctcttgagtagctgggattacaggcaacaattttaagtgaagtg aagtttcaggatctcgagcaaagttgtataacctataatcatattcaagattcacaggtcataaacgtgtcatattcttg ggattgagcgacccattgcacagcatttagatgtgcttctagaatggagctcctccttcctatatggagggcagtttata tggtgtacttacctgaccaccaaaaagatttggctctaaaaaagcttcaggtggccgggcatggtggttcacccctgtaa tccagcactttgggaggcaggtgggcagatcacctgaggtcagaagttcagacagctggacatatggtgaaacctcatct ctactaaaaatacaaaaattagactgggcatggtagtgggcgcctgtaatcccagctagtcgggaggctgaggcaggaga atcccttcaactcggacggcagagtttgcagtgaggccgagatcgtgtcactgcagtccagcctgggtgacagagcaaga ctccatctcaaaaaaagtaaaaaaaaaaaaaagaaaaaaaaaagcttcagagccagcagggatcatgctgtaataaatac ttaacatcaacactgatctttaaatgctttagcacaatcaaatataaataacaaacacacacataaatgcaaaataaatg aattagggagatagatgaaataagattgtggaaatagtaatgtttgttaaagctggatggtgatccttgtactattcact ctactctagtgtgtatttgaaaattaccattaggctggttatggtggctcatgcctgttaatcccggcattttggaaggc tgaggcaggcggattacttgagctcaggagtttagagtctgcctgggcaacatggcaaaatcccatctctacaaaaaatt agctggcatgatggcacactcctgtagtcccagctccttgaggggctgaggcagagaatggcttgaacctgagaggctaa agctgcagtgagccaagatcatgccactgcactccagcctgggtgaccaagtgagaccctgtctcaaaaaaaaaaaaaaa aaaaagaaaagaaaattcccattaaagcacaaaggcccacttattgaagctattaaaatacaggttggggccggctgggc atcgcgtcacgcctgtaatcccagcactttggaaggccgaggtaggcgagtcacgagttcaggagatcgagaccatcctg gctaacacggtgaaaccccatctctactaaaaatacaaaaaaaaaaatcagccgggcatggtggcgggagcctatagtcc cagctactcgggaggctgaggcaggagaatggcatgagcccgggaggcggagcttgcagtgagccaaaatcacaccactg cactccagcctgggcaacagatcgagactccatctgaagaaaaaaaaaatacaggttgggaccacagtggctcatgcctg taatcctagtactttgggagtccgaagtaggtggatcacctgaggtcaggactttgagaccagcctggccaacatggcaa aaccccatctctactaaaaaatatacaaaaattagctgggcgtggtggtgggtgcctgtaatcccagctactcaggaggc tgaggcagaagaatcacaacaaccagggggatggtggttgcaatgagccaagatcatctccacttcactccggcccaggc aaaagagtgagagtcatcttaaaaaaaaaaaaaaaaaaaaaaaaaaaatacagattaggcattcctaatctgaaaaattt ggctccaaaatgctccagtcgagcatttcctttgagtgtcatgtgggtgctcaaaaagttagatttttggaccattttca gatttcagagttttggattagggatgctcgactggtaagtaatcgagatattccaaaaatctggacaaatctgaaatcca aaatgcttggaatagcagatactcaactggtagcactccctggaagaatatgcaccaaactgatagcagtggttaccttc tggtgaggaggggaaagaaccaagattagcagtaggatcaacatatattttaatgttttctgtatttttattacttgtat aatttaaacattttaaattagtaataatgaacaatcatgaaactatggatgatttagtccagcaaaatatccaattggga accctcatccttctgcagagcccaaatggcgcagtgggaaatgctgcagaatcttgacagcccctttcaggatcagctgc accagctttactcgcacagcctcctgcctgtggacattcgacagtacttggctgtctggattgaagaccagaactggtga ggccttcaggaagttgggggaatgaaaaaggtggccttccacttctgggcccccgggatcctggaatcattaatggcagg aaggggttggaaagcctcaggactacagtaacactgcagagacactaatacttcttattcctggtcccaggcaggaagct gcacttgggagtgatgattccaaggctaccatgctattcttccacttcttggatcagctgaactatgagtgtggccgttg cagccaggacccagagtccttgttgctgcagcacaatttgcggaaattctgccgggacattcaggtacttggaacggttg ggagtgatggggtagcactgggagcagagcatagaggagtaaggtttggagaatagaatagtacctggaggtggcaaggg agacgggaacaaatgtggggaaaggaggacagagtctggacttggggaatcactagcagagagaagggttgcatatacgt gacactgttgggaggatgctatggtgaaaagacaaagggctaagaaccccgaaggaggaggaaatactgtggacattggt ggggagggtctagggcaataggtcattgagagtggttgaattggatcaatcctttctgtttacctttctgttagcccttt tcccaggatcctacccagttggctgagatgatctttaacctccttctggaagaaaaaagaattttgatccaggctcagag ggcccaattggtgaggacaattcagtggtaatgttggaaactcctgaagtagagaggaaccatggaaaggactcagggag ttgtctcagaacaggatccccccgacatcctgtggtataatttcaggcctgaacttaaggcatgaaaggccagagttaaa acgtgctcagagcctcttttttcaggaacaaggagagccagttctcgaaacacctgtggagagccagcaacatgagattg aatcccggatcctggatttaagggctatgatggaggttagtagatgtggtaggagttagggttgacagtgttcagcctaa cacctccctgagaagcagcctcatcggggtcctctcccctctgcagaagctggtaaaatccatcagccaactgaaagacc agcaggatgtcttctgcttccgatataagatccaggccaaaggtaggaagcacattgaggggctggagaaagataagtgc ctgctgagaagccggagctggaagtgaacaggagaaagctccgatgagcagtagtcactgtcagacacaccccactgact acagtcctgctgccgtgcaaagctggaatcgtgctttgtggaggctgagctggaggtgacagctgagagacagtaaattg ttgaggaaatgcatggaaaactaacagtgttttatttgagggggtgtctggtccaagatgaccacttcagaatttgcctg gagggtcccacaggtgcctgtgctttgcttggtttccctttcttcctccgccacaaaattcctccttcctgactctgact gagaccccagtcaggaaggagaggaaagaacccctggactgactcctgttcccaccatccagggaagacaccctctctgg acccccatcagaccaaagagcagaagattctgcaggaaactctcaatgaactggacaaaaggagaaaggtgggaggcagc agaacagaacatgtgggcaacaaggacctgaaaaaatgagggatgttgggaaccctggtaatctagcgctggcttctttc tttcttcatccccagttgggtggtggagggtgaaagggagagatgctcaacactcacattatctctttcccaggaggtgc tggatgcctccaaagcactgctaggccgattaactaccctaatcgagctactgctgccaaagttggaggagtggaaggcc cagcagcaaaaagcctgcatcagagctcccattgaccacgggttggaacagctggagacatggtgagaggtaccacccca accctcgtcctcgccatgcgctgtgatttgtaagttgcagtgccctgcatatagcaagagatactgttctctatttgtct ctgctccccagaatagagccctgctccctgcctgactgcagctctattctgcctcctcagcctcaccacgcagggaagcc cagaagtcccagtctccttcagggaaaggaatgaattaacccacaatctggttttgcttcttttttttaatcacccagaa atatatatatatgtattttttttttactgcaacgaatacaatgacaagaaaggaagggaaggaaggaaggaagagaaaat tacctattacctagcttattaaacaaaaatggaatcatattgtccatactattttgaaatccatggggttttttttaagc ttaacagtattttatatatatatatatatatatatatatatatatatatatatatatatatatatttttttttttttttt ttttttttttttttgagacggagtctctctctgttccctggctggcggagcggagtcggcacgatctcagctcactgcaa cttccaactcccacggttcaagccaattctcctgtctcagcctcccgagcctgggattaccaggcacacaccagcctggc tagtttttttgattttttagtagagacgatgtttctccatgttggccaggctggtctcaaactcctgacttcaggtgatc cacccaacttgggctcccaaagtgctgggattacaggcgtgacgaccatgcccggccaacagtatattatatttatccat gttatttcttatgtccacacaacagtcccctatatggtggtaacataatttaattaatgaactcctattttcagctattt aggttattttcaatttcttgttaccttttgccaggaaacgtatattttatggtaattatattgtgttgtagaaaaatcac tagtctagtccaacttgcttgaaaaatagctactttttaactattttctcatttaaaaatttattataatttagtctttt agaaatataccaggccaggcatggcgtctcatgcctgttatcctagtactttggaaggctgaggacggaggatcacttca gtcttggggtttgagaccagcccgggaaacataacaagaccccatctctacaaaaaaaaaaaattgtttttaattaggca tgtccgacacagtggctcacacatgtggccagcactgtgggaaggccaaggtgggtggatcacttgagggtcaggagttc aagaccagcctggccaatgtggtgaaaccccatctctactaaaaatacaaaaatttgccaggtgtggtggcgcatgcctg tattcccagctactcaggaggctaaggcaggaaatcacttgaactcggaggcagaggttgcagtgagctgtgacaatgcc actgtactccagcctgggtgacagagcgagctccgtctcaaaaaaaaaaaaaaaagattaggcatggtggcacacgcctg tagaccctagctactcaggaggctgaggtgggaggattgcttgagcccaggtgttggaggctgcagtgagccatgattat accactgtagtccagcctggacaacagaacgagaccctgtctctaaaagtatatatgtacacataccataatacccagct actgaggaggctgaggcagaaagagtgcttgagtccaggagtttgatgtcagcctgagcaatatagcaagaccctcacct cttaaaaaaatttaaagtagattaaaaaaataccacaattgctcaggtagattaaaaaaataccacaattgctcaggtag attattgaaaaacaggcatatagtacttatggtacaggaccagcatgcatgcatgcatgcattgattgattgattgattg attgattgagacagggtctctctctgtctcccaggctggagtgcctggccttaagtgatctgcccacctttgcttcccaa agtgctgagattacaggtgtgagccaccatgtcagctggcgaggctttttaaaagatagttccaagtgttacagctcttt taggatttgtctagcaggctttcaggtttttgccagaaaccacccccacccccaccaaaaaaaaaaaaaaaaaaaagata tgtacaagttcccagatagtgttcccaactgaatctatttctcatgtgtagtgtatggttgttttcctgtcaccacattg ctgattattattatttttaattatagagacagtaaagtacagtagttaaaaatgtgagttggggctgggtgcagtggctc acacctgtaatcccagcactttgggaggccaaggtgggcggatcacctgaggtcaggagttcaagaccagcttggccaac atggcaaaaccccgtctcgactaaaaatatatatatataagttagccgggcgtggtggcaacattacctgtaatcccagc tac cgggaggccaacaggcaggagaatctcttgaatccaggaggtggaggttgcagtgagccagatcacaccattgcac tccagcctggatgacaagagagtgagactgtctaaaaaaaaaaaacaaagtgtgagttgtacaatgagactgcctgggat cacatacaagcttcatcccttactagttgtattgaccctaaagcaagtcactaacctttctgtgccctccagttttatca tctgtaatgtggggaaaataatagtacctgcctcagagggttgttttgaggattaaatgcattaatatgtggaaagggct taatataagttgtacatagcatatgaaaactgttatgttaaatctattagcagttttatatgtgaaaatagctttgattt tcatttcttggattatgaatcatgttgaataatcctttatatgcttcctggattctttttttttcttccccccagtcagt ttctgactcttctcatatttatagagagatcttggaacctggatgggggaatccaggaaactcatggattccttcttcct gaattttatcacccaggttcacagctggagcaaagctgttgtttcacctgaggcagctgctgaaggagctgaagggactg agttgcctggttagctatcaggatgaccctctgaccaaaggggtggacctacgcaacgcccaggtcacagagttgctaca gcgtctgctccacaggtctagaggccaggcaggaaccctgggggaaagaaggaacaagggaagccattcttacacatact gagctatatattctctccacacctctctctcctcgagcctttgtggtagaaacccagccctgcatgccccaaactcccca tcgacccctcatcctcaagactggcagcaagttcaccgtccgaacaaggttggcattccagaactcattcccacttcctt tttccaaccctgccactgtgtattttctggctttacagctactgcccactcttggctttttcagtctttcctgaatctcc ctacctcgttgataccccatcgtcctctttttcaaacacctagcctatacaaaagccgactccgaccacatttccctata ccccttgacttccccaggctgctggtgagactccaggaaggcaatgagtcactgactgtggaagtctccattgacaggta aattggagcaggtgaagggtggccaggacacgggctgctggggtggaggagatactcactcttcacaacagggccctagg gctatatccttcctccttccaatcctacctcacagaaattataattcatttcttttgttgaacacttactttgtgacatg cagcatgtcagctactcatttaattgtcacaccaaccccatgaataaactattaccagtgcactgtacaaacaaagatac aggcttagagagactgattacatctcttctcaaggccacatagctagtgagctcaagtcgggtttgaaccgaggtctgtc tgatcccaaagacgaaactcctaacttccatactcttttgcccaatgattttttttaaatttatttcttttcaggaatcc tcctcaattacaagggtaggtgcttgacaaggacactgcaaacatctgtacagtgtatgacctgcagaaccgggggattt gggaaatggacaaagggagatggcgagatctgaaatggaagtggaacttcagttttttttttttctgctgagtttttaca ataattccattccttgtctccatgtatcttcctcctggaacagcttccggaagttcaacattctgacttcaaaccagaaa actttgacccccgagaaggggcagagtcagggtttgatttgggactttggttacctggtaagaatagtttgtgacctatg cttttattactatttttattttttcgagacggagtctcactctgtcccccaggctggagtgcagtggtgccatcttggct cacaggaacctccgccctccccggttcaagcaattcttctgtctcagcctcctgagtacgtagagctataggcagcacac caccatgcccggctaatttttgtatttttagtagagatagggtttcaccatattggtcgggctggtctcgaactcctgac ctcaggtgatccgacccgcctcagcctcccaaagtgctgggatcacaggcatgagccaccatagctggcctgcttttagt ccaaaggaacaggggttgggggaagttcccagggcttgagaggtcttgaagccaaacaggggttccagggagactagggt gcccactctggcattttctctccttcccttcaattcacagactctggtggagcaacgttcaggtggttcaggaaagggca gcaataaggtgagatctggacagaggactcgaggcagggggagcttgccaaagagccttctgatgactatgtctttgcct gtcccagaggggccactaggtgtgacagaggaactgcacatcatcagcttcacggtcaaatatacctaccagggtctgaa gcaggagctgaaagtgagtgaaaatggagggcaaggagagagaaagcagctttggaagaaggcataagaaggggataaac agaagcctcttggggagggttagcactcctttcctctaacaaatacctgcagctagaaacatcacatccctctctgtgac tcctgtcttctccccacacacggacaccctccctgtggtgattatttccaacatgaaccagctctcaattgcctgggctt cagttctctggttcaatttgctcagcccaaaccttcaggtaggggagtggggccgacaggtcccggcgcgagagcagggg tgtggaagcttggtgtgataggttgcttctgagccagcctacactgctcccacccctgcagaaccagcagttcttctcca acccccccaaggccccctggagcttgctgggccctgctctcagttggcagttctcctcctatgttggccgaggcctcaac tcagaccagctgagcatgctgagaaacaagctgttcggtacagatttccttttctctcagcctttccccagccttagtct tttctgtccctctgtcctatctatcccaggacccctggcttccctcacatatctgtggctatctgtcccacagggcagaa ctgtaggactgaggatccattattgtcctgggctgacttcactaaggtaactccctgaatcctgtggagctgctggatct agccccacattccaaatactggccttcccacgtgccctccttccctacaccagaggcaactcctcagcttttgctacctt tccattcctccagcgagagagccctcctggcaagttaccattctggacatggctggacaaaattctggagttggtacatg accacctgaaggatctctggaatgatgggtaaggccttggtcacccttccctcatgggcttgtgcttccgggcttgagag tggagtctctgcaccctcacgtggcaagcagggagagagagcaaagcacggtgcaggccacgtctcctcacatttgttaa gaataataaggccgggtgtggtggctcacacctgtaatcccagcactttgggaggccgaggcgggcggatcatgaggtca ggagatcgagaccatcctggctaacacggtgaaaccccgtctctactctaaaaatacaaaaaattagccgggcgtggagg cagacaccctgtagtcccagctactcaggaggctgaggcaggaaaatggcgtgaacctgggagatggagcttgcagtgag ccgagattgcgtcactgccctccagccttggggtgacgtagcaagactccgtctcaaaaaaaaaaaaaaaaaacaaccaa taatagccataaacagtgtttttgtgaagcactcctacattccagagcttgatgggtgctcttcattaattctctcatct catccttacaaccatgctgagtggtgggttttgccagcttcatttcatgtgaggaaactgagtttcagagaagttaaaga acttacccaagggacacagttgatattcaaatccaggcctatgtgactccaagcccatgctctttccaccacactgccta ccaacttgtgtagcatttggcttttaaaagtgctattcatgaccaggcacgatggctcacgccttgtaatcccagcattt tgggaggccgaggtgggtggatcacctgaggtcaggagtttgagaccagcctggccaacatggcgaaaccccatctctat taaaaatacaaaaattagccgggtgtggtggtgggcgcctgtaatcccagctactcaggaggctgaggaggagaatcgct tgaatttaggagagaaggttacagtgagccaagatcgtgccattgcactccagcctgggtgacagagcaagactctgtct caaaacaaaaccaaaaaaaagtgctatttgtggccaggcgtggttgctcatgcctgtaatcctagcatttttggggaggc tgaggagtacagatcacttgagcccaggagttcaaaactaccctgggccacgtggtgaaaccccaaaccccgtctctacg aaaaatacaaaagttagccaggatgggtggtgtgcacctgtggtcccagctactctggaggctgagaggtggggaagatt gcttgagcccgggaggtcgaggtggcagtgagctgtgatcatgccactattctccagcctgggtgacagaatacaccctg tctccctgtctcccagaaaaaaaaaaaagtgctgttcatctgtgtgatctcactgaatcttcgtacttcaaaccctcgga aggtggctattgtcagcaaagtgaagtgacttgtaaaagataaaaaaaagctaagtggcagggcttggtccaaagcctgg attccaaacctgggctgtttctccatacaaggggagcagggaggcaggggcctgggggggcagggtgttgggcggtgtca cacgtgacacactgtgctccagacgcatcatgggctttgtgagtcggagccaggagcgccggctgctgaagaagaccatg tctggcacctttctactgcgcttcagtgaatcgtcagaagggggcattacctgctcctgggtggagcaccaggatgatgg tagctgctctgccctgccattcccacagcctctcctttctgcctggctctcctctggcccctctgcctgccttgcttcgc tggctctgaactgaatgctcagtggtttgggactgggcagccagagagtcagagagctccaaggcccggcctcttccctc aagcccgcctgttcctgcattcactctccagacaaggtgct atctactctgtgcaaccgtacacgaaggaggtgctgca gtcactcccgctgactgaaatcatccgccattaccagttgctcactgaggagaatatacctgaaaacccactgcgcttcc tctatccccgaatcccccgggatgaagcttttgggtgctactaccaggagaaaggtgggaatcgttgacatacttcattg ctagattgcagagatctaccagacatccatagatcccactccttcctttaaagcatgggaaaactgatatctagaggaat taagggattcgtccatgggatactgctggttactatggggatgagactgccaggaccatctgcactaggggaaaacctca ggctatatgtctggcccactgatcttctctgcttcttgtatatgttcctcacagttaatctccaggaacggaggaaatac ctgaaacacaggctcattgtggtctctaatagagtgagatatgaactgttcattcatcctccctaatccttattggctct gcttcagtgaatcgtcaaaagggggcattaccttctcctgggtggagcaccaggatgatggtcagctgctctgccctgcc attcccacagcctctcctttctgccttctcctaagctgcccctattccagtctccccagccttccctccctcctagcccc actctagttttttctggttctagtctctcctatctcatatttttctgctgccatccttaggttgtctccacaggggtttc tggataataatgatcataatcactggtgttaaggggtacctacttgatgcaagcatggagctttttttttttccagacag ggttttgttctgtcgcccaggctggagtgcagtggtgtgatcctggctcactgcagcctcgacctcctgagctcaagcaa tacaggcatgcatcaccaaactcagctaattttttttgtattttttgtagagatggggtcttaccatgttgacgcatcag gctgttctgaactcctggactcaagcaatccacccaccttggcctcccaaaagtcagggattacaggcgtgcgaccacac cccgcatatatatatttttttttttttttttttttttttttttttgagacagggtctctgttatccaggctggagttgca gtggataatatgactacgagccttgacctaggggttgaagcaatgctcctgcctcagccaccaagtgctgagactacagg cacacgccaatctacactcaatcacactcagctaattttttaaattttttgtagggatggggtatcactgtgtttgccca ggctggtcttgaactcctggcctcaagcagtctcctgccttggcctcccaaattgccgggattgtaggaatgagccatgg cacttggctgggggatagaattttttttttttttttttttttttttttttttgagacagtctcactctcattgcccgggc tggagtgcagtggtgcaatttcagctcactgcaacctctgcctcccaggctcaagcaattctcctgcctcagcctataga gtagctgggattacaggcgagcgccacccatgcctggttaatttttgttttttttttgagacagagtctcgccctgttgc ccaggctggagtgcagtggcacgatctcagctcactgcaacctctgcctcccaggctcaagcaattctcctgcctcagcc tcctgagtactgggactacaagcgcgcacaaccaccacacctggtaatttttgtatttttagtagagacagggttttacc atattggccaggctggtctcaaactcctgacctcatgatccgacccaccttggcctcccaaagtgcagggattacaggcg tgagcctctgcacccggcctaacttttgtatttttagtagaaacagggtttcaccatgttggccaggctggtcatgagct cctggcctcaagtgatctgcccgcctcagcctcccaaagtgcttggattacaggtgtgagccacctggcctgagagttta ttatgcgccaggcactaggcaaatggtttgcatttattttctcattttattgaatctacaaaatagtcctgtgaagtaaa cactgttactgttttcagctaaggaactggatttagagtagtcaagttttgtacctaaggtacgtggctaatgatacagg tctgttagattccgtagccctgattttaaccaccctactgcctctcaagaattactaggtattgttctcatttatagatg ataaatctgaggctcagaaaagttaggccacttgcctaaggtcccccagccaggattcaaactccaggaggcctgattcc aaacccatgctctttagccctccgccctactgccttcttagactagcttctgcttattctaccattcctgatttcatttg aaccactgagccctgcccctttgtctgtctttgggta ccaggcaggtggatgaactgcaacaaccgctggagcttaagc cagagccagagctggagtcattagagctggaactagggctggtgccagagccagagctcagcctggacttagagccactg ctgaaggcagggctggatctggggccagagctagagtctgtgctggagtccactctggagcctgtgatagagcccacact atgcatggtatcacaaacagtgccagagccagaccaaggacctgtatcacagccagtgccagagccagatttgccctgtg atctgagacatttgaacactgagccaatggaaagtaagtgatgagatggagtggcacacattccctttcctacctcttct ccctctcccattacagaaaaagctgaactccaagctcctcattggagagaggtccatctgtgattcctttttttaggaat tacacatgccttcccccacctccctgctctttcatcccacaagttcccactcaggctcttcccaggcctttcctgccatc ctccctcccttgggctgctgggttgggaactcctaactaagatcggggcctcacttttctctctggattacctagtcttc agaaactgtgtaaagattgaagaaatcatgccgaatggtgacccactgttggctggccagaacaccgtggatgaggttta cgtctcccgccccagccacttctacactgatggacccttgatgccttctgacttctaggaaccacatttcctctgttctt ttcatatctctttgcccttcctactcctcatagcatgatattgttctccaaggatgggaatcaggcatgtgtcccttcca agctgtgttaactgttcaaactcaggcctgtgtgactccattggggtgagaggtgaaagcataacatgggtacagagggg acaacaatgaatcagaacagatgctgagccataggtctaaataggatcctggaggctgcctgctgtgctgggaggtatag gggtcctgggggcaggccagggcagttgacaggtacttggagggctcagggcagtggcttctttccagtatggaaggatt tcaacattttaatagttggttaggctaaactggtgcatactggcattggccttggtggggagcacagacacaggatagga ctccatttctttcttccattccttcatgtctaggataacttgctttcttctttcctttactcctggctcaagccctgaat ttcttcttttcctgcaggggttgagagctttctgccttagcctaccatgtgaaactctaccctgaagaaagggatggata ggaagtagacctctttttcttaccagtctcctcccctactctgccccctaagctggctgtacctgttcctcccccataaa atgatcctgccaatctaatgtgagtgtgaagtttgcacactagtttatgctacctagtctccactttctcaatgcttagg agacagatcactcctggaggctggggatggtaggattgctggggatttttttttttttaaagagggtctcactctgttgc ccaggctagagtgcaatggtgcaatcacagctcactgcagcctcaacctcctgggttcaagcaatcctcctacctcagcc tcctgggtagctagcaccatggcatcgccaccatgccctattttttttttttaaagacagggtcttgctatattgcccag gctggtcttgaactgggctcaagtgatcctcacgccttgcctcccaaagtgctgggattataggcatgagccactgtgct tggccaggatttttttttttttttttttgagatggagtttctctcttgttgtccaggctggagtgcaatggtgtgatccg gggaattc (SEQ ID NO: 11995) cagctggaattcggggcggcggcgcagactgggagggggagccgggggttccgacgtcgcagccgagggaacaagcccca accggatcctggacaggcaccccggcttggcgctgtctctccccctcggctcggagaggcccttcggcctgagggagcct cgccgcccgtccccggcacacgcgcagccccggcctctcggcctctgccggagaaacaggatggcccaatggaatcagct acagcagcttgacacacggtacctggagcagctccatcagctctacagtgacagcttcccaatggagctgcggcagtttc tggccccttggattgagagtcaagattgggcatatgcggccagcaaagaatcacatgccactttggtgtttcataatctc ctgggagagattgaccagcagtatagccgcttcctgcaagagtcgaatgttctctatcagcacaatctacgaagaatcaa gcagtttcttcagagcaggtatcttgagaagccaatggagattgcccggattgtggcccggtgcctgtgggaagaatcac gccttctacagactgcagccactgcggcccagcaagggggccaggccaaccaccccacagcagccgtggtgacggagaag cagcagatgctggagcagcaccttcaggatgtccggaagagagtgcaggatctagaacagaaaatgaaagtggtagagaa tctccaggatgactttgatttcaactataaaaccctcaagagtcaaggagacatgcaagatctgaatggaaacaaccagt cagtgaccaggcagaagatgcagcagctggaacagatgctcactgcgctggaccagatgcggagaagcatcgtgagtgag ctggcggggcttttgtcagcgatggagtacgtgcagaaaactctcacggacgaggagctggctgactggaagaggcggca acagattgcctgcattggaggcccgcccaacatctgcctagatcggctagaaaactggataacgtcattagcagaatctc aacttcagacccgtcaacaaattaagaaactggaggagttgcaccaaaaagtttcctacaaaggggaccccattgtacag caccggccgatgctggaggagaggatcgtggagctgttcagaaacttaatgaaaagtgcctttgtggtggagcggcagcc ctgcatgcccatgcatcctgaccggcccctcgtcatcaagaccggcgtccagttcactactaaagtcaggttgctggtca agttccctgagttgaattatcagcttaaaattaaagtgtgcattgacaaagactctggggacgttgcagctctcagagga tcccggaaatttaacattctgggcacaaacacaaaagtgatgaacatggaagaatccaacaacggcagcctctctgcaga attcaaacacttgaccctgagggagcagagatgtgggaatgggggccgagccaattgtgatgcttccctgattgtgactg aggagctgcacctgatcacctttgagaccgaggtgtatcaccaaggtctcaagattgacctagagacccactccttgtca gttgtggtgatctccaacatctgtcagatgccaaatgcctgggcgtccatcctgtggtacaacatgctgaccaacaatcc caagaatgtgaacttcttcactaagccgccaattggaacctgggaccaagtggccgaggtgctcagctggcagttctcgt ccaccaccaagcgggggctgagcatcgagcagctgacaacgctggctgagaagctcctagggcctggtgtgaactactca gggtgtcagatcacatgggctaacttctgcaaagaaaacatggctggcaagggcttctcctactgggtctggctagacaa tatcatcgaccttgtgaaaaagtatatcttggccctttggaatgaagggtacatcatgggtttcatcagcaaggagcggg agcgggccatcttgagcactaagcccccaggcaccttcctgctgcgcttcagtgaaagcagcaaagaaggaggcgtcact ttcacttgggtggagaaggacatcagcggtaagacccagatccagtccgtggaaccatacacaaagcagcagctgaacaa catgtcatttgctgaaatcatcatgggctataagatcatggatgctaccaatatcctgttgtctccacttgtctatctct a cctgacattcccaaggaggaggcattcgggaagtattgtcggccagagagccaggagcatcctgaagctgacccaggt agcgctgccccatacctgaagaccaagtttatctgtgtgacaccaacgacctgcagcaataccattgacctgccgatgtc cccccgcgctttagattcattgatgcagtttggaaataatggtgaaggtgctgaaccctcagcaggagggcagtttgagt ccctcacctttgacatggagttgacctcggagtgcgctacctcccccatgtgaggagctgagaacggaagctgcagaaag atacgactgaggcgcctacctgcattctgccacccctcacacagccaaaccccagatcatctgaaactactaactttgtg gttccagattttttttaatctcctacttctgctatctttgagcaatctgggcacttttaaaa'atagagaaatgagtgaat gtgggtgatctgcttttatctaaatgcaaataaggatgtgttctctgagacccatgatcaggggatg (SEQ ID NO: 11996) cgacagcgaccagatcaaggaggaactgccggagccctttgagcatcttctgcagagaatcgcccggagacccaagcctc agcagttctttggattaatgggcaaacgggatgctggacatggccagatctctcacaaaagacataaaacagattccttt gttggactaatgggcaaaagagctttaaattctgtggcttatgaaaggagtgcaatgca (SEQ ID NO: 11997) gagagtgcggagcgaccacgtgcgctcggaggaaccagagaaactcagcaccccgcgggactgtccgtcgcaaaatccaa catgaaaatcctcgtggccttggcagtcttttttcttgtctccactcagctgtttgcagaagaaataggagccaatgatg atctgaattactggtccgactggtacgacagcgaccagatcaaggaggaactgccggagccctttgagcatcttctgcag agaatcgcccggagacccaagcctcagcagttct tggattaatgggcaaacgggatgctgattcctcaattgaaaaaca agtggccctgttaaaggctctttatggacatggccagatctctcacaaaagacataaaacagattcctttgttggactaa tgggcaaaagagctttaaattctgtggcttatgaaaggagtgcaatgcagaattatgaaagaagacgttaataaactacc taacattatttattcagcttcatttgtgtcaatgggcaatgacaggtaaattaagacatgcactatgaggaataattatt tatttaataacaattgtttagggttgaaaattcaaaaagtgtttatttttcatattgtgccaatatgtattgtaaacatg tgttttaattccaatatgatgactcccttaaaatagaaataagtggttatttctcaacaaagcacagtgttaaatgaaat tgtaaaacctgtcaatgatacagtccctaaagaaaaaaaatcattgctttgaagcagttgtgtcagctactgcggaaaag gaaggaaactcctgacagtcttgtgcttttcctatttgttttcatggtgaaaatgtactgagattttggtattacactgt atttgtatctctgaagcatgtttcatgttttgtgactatatagagatgtttttaaaagtttcaatgtgattctaatgtct tcatttcattgtatgatgtgttgtgatagctaacattttaaataaaagaaaaaatatcttg (SEQ ID NO:11998) gcgccgcaaggcactgagcaggcgaaagagcgcgctcggacctccttcccggcggcagctaccgagagtgcggagcgacc agcgtgcgctcggaggaaccagagaaactcagcaccccgcgggactgtccgtcgcaaaatccaacatgaaaatcctcgtg gccttggcagtcttttttcttgtctccactcagctgtttgcagaagaaataggagccaatgatgatctgaattactggtc cgactggtacgacagcgaccagatcaaggaggaactgccggagccctttgagcatcttctgcagagaatcgcccggagac ccaagcctcagcagttctttggattaatgggcaaacgggatgctgattcctcaattgaaaaacaagtggccctgttaaag gctctttatggacatggccagatctctcacaaaagacataaaacagattcctttgttggactaatgggcaaaagagcttt aaattctgtggcttatgaaaggagtgcaatgcagaattatgaaagaagacgttaataaactacctaacattatttattca gcttcatttgtgtcaatgggcaatgacaggtaaattaagacatgcactatgaggaataattatttatttaataacaattg tttggggttgaaaattcaaaaagtgtttatttttcatattgtgccaatatgtattgtaaacatgtgttttaattccaata tgatgactcccttaaaatagaaataagtggttatttctcaacaaagcacagtgttaaatgaaattgtaaaacctgtcaat gatacagtccctaaagaaaaaaaatcattgctttgaagcagttgtgtcagctactgcggaaaaggaaggaaactcctgac agtcttgtgcttttcctatttgttttcatggtgaaaatgtactgagattttggtattacactgtatttgtatctctgaag catgtttcatgttttgtgactatatagagatgtttttaaaagtttcaatgtgattctaatgtcttcatttcattgtatga tgtgttgtgatagctaacattttaaataaaagaaaaaatatcttgaaaaaaaaaaaaaaaaa (SEQ ID NO: 11999) cgacagcgaccagatcaaggaggaactgccggagccctttgagcatcttctgcagagaatcgcccggagacccaagcctc agcagttctttggattaatgggcaaacgggatgctggacatggccagatctctcacaaaagacataaaacagattccttt gttggactaatgggcaaaagagctttaaattctgtggcttatgaaaggagtgcaatgcagagagtgcggagcgaccacgt gcgctcggaggaaccagagaaactcagcaccccgcgggactgtccgtcgcaaaatccaacatgaaaatcctcgtggcctt ggcagtcttttttcttgtctccactcagctgtttgcagaagaaataggagccaatgatgatctgaattactggtccgact ggtacgacagcgaccagatcaaggaggaactgccggagccctttgagcatcttctgcagagaatcgcccggagacccaag cctcagcagttctttggattaatgggcaaacgggatgctgattcctcaattgaaaaacaagtggccctgttaaaggctct ttatggacatggccagatctctcacaaaagacataaaacagattcctttgttggactaatgggcaaaagagctttaaatt ctgtggcttatgaaaggagtgcaatgcagaattatgaaagaagacgttaataaactacctaacattatttattcagcttc atttgtgtcaatgggcaatgacaggtaaattaagacatgcactatgaggaataattatttatttaataacaattgtttag ggttgaaaattcaaaaagtgtttatttttcatattgtgccaatatgtattgtaaacatgtgttttaattccaatatgatg actcccttaaaatagaaataagtggttatttctcaacaaagcacagtgttaaatgaaattgtaaaacctgtcaatgatac agtccctaaagaaaaaaaatcattgctttgaagcagttgtgtcagctactgcggaaaaggaaggaaactcctgacagtct tgtgcttttcctatttgttttcatggtgaaaatgtactgagattttggtattacactgtatttgtatctctgaagcatgt ttcatgttttgtgactatatagagatgtttttaaaagtttcaatgtgattctaatgtcttcatttcattgtatgatgtgt tgtgatagctaacattttaaataaaagaaaaaatatcttggcgccgcaaggcactgagcaggcgaaagagcgcgctcgga cctccttcccggcggcagctaccgagagtgcggagcgaccagcgtgcgctcggaggaaccagagaaactcagcaccccgc gggactgtccgtcgcaaaatccaacatgaaaatcctcgtggccttggcagtcttttttcttgtctccactcagctgtttg cagaagaaataggagccaatgatgatctgaattactggtccgactggtacgacagcgaccagatcaaggaggaactgccg gagccctttgagcatcttctgcagagaatcgcccggagacccaagcctcagcagttctttggattaatgggcaaacggga tgctgattcctcaattgaaaaacaagtggccctgttaaaggctctttatggacatggccagatctctcacaaaagacata aaacagattcctttgttggactaatgggcaaaagagctttaaattctgtggcttatgaaaggagtgcaatgcagaattat gaaagaagacgttaataaactacctaacattatttattcagcttcatttgtgtcaatgggcaatgacaggtaaattaaga catgcactatgaggaataattatttatttaataacaattgtttggggttgaaaattcaaaaagtgtttatttttcatatt gtgccaatatgtattgtaaacatgtgttttaattccaatatgatgactcccttaaaatagaaataagtggttatttctca acaaagcacagtgttaaatgaaattgtaaaacctgtcaatgatacagtccctaaagaaaaaaaatcattgctttgaagca gttgtgtcagctactgcggaaaaggaaggaaactcctgacagtcttgtgcttttcctatttgttttcatggtgaaaatgt actgagattttggtattacactgtatttgtatctctgaagcatgtttcatgttttgtgactatatagagatgtttttaaa agtttcaatgtgattctaatgtcttcatttcattgtatgatgtgttgtgatagctaacattttaaataaaagaaaaaata tcttgaaaaaaaaaaaaaaaaa (SEQ ID Nθ:12000) gaaaaagccttccaccctcctgtctggctttagaaggaccctgagccccaggcgccacgacaggactctgctgcagaggg gggttgtgtacagatagtagggctttaccgcctagcttcgaaatggataacgtcctcccggtggactcagacctctcccc aaacatctccactaacacctcggaacccaatcagttcgtgcaaccagcctggcaaattgtcctttgggcagctgcctaca cggtcattgtggtgacctctgtggtgggcaacgtggtagtgatgtggatcatcttagcccacaaaagaatgaggacagtg acgaactattttctggtgaacctggccttcgcggaggcctccatggctgcattcaatacagtggtgaacttcacctatgc tgtccacaacgaatggtactacggcctgttctactgcaagttccacaacttcttccccatcgccgctgtcttcgccagta tctactccatgacggctgtggcctttgataggtacatggccatcatacatcccctccagccccggctgtcagccacagcc accaaagtggtca ctgtgtcatctgggtcctggctctcctgctggccttcccccagggctactactcaaccacagagac catgcccagcagagtcgtgtgcatgatcgaatggccagagcatccgaacaagatttatgagaaagtgtaccacatctgtg tgactgtgctgatctacttcctccccctgctggtgattggctatgcatacaccgtagtgggaatcacactatgggccagt gagatccccggggactcctctgaccgctaccacgagcaagtctctgccaagcgcaaggtggtcaaaatgatgattgtcgt ggtgtgcaccttcgccatctgctggctgcccttccacatcttcttcctcctgccctacatcaacccagatctctacctga agaagtttatccagcaggtctacctggccatcatgtggctggccatgagctccaccatgtacaaccccatcatctactgc tgcctcaatgacaggttccgtctgggcttcaagcatgccttccggtgctgccccttcatcagcgccggcgactatgaggg gctggaaatgaaatccacccggtatctccagacccagggcagtgtgtacaaagtcagccgcctggagaccaccatctcca cagtggtgggggcccacgaggaggagccagaggacggccccaaggccacaccctcgtccctggacctgacctccaactgc tcttcacgaagtgactccaagaccatgacagagagcttcagcttctcctccaatgtgctctcctaggccacagggccttt ggcaggtgcagcccccactgcctttgacctgcctcccttcatgcatggaaattcccttcatctggaaccatcagaaacac cctcacactgggacttgcaaaaagggtcagtatgggttagggaaaacattccatccttgagtcaaaaaatctcaattctt ccctatctttgccaccctcatgctgtgtgactcaaaccaaatcactgaactttgctgagcctgtaaaataaaaggtcgga ccagcttttcccaaaagcccattcattccattctggaagtgactttggctgcatgcgagtgctcatttcaggat (SEQ ID NO: 12001) aattcagagccaccgcgggcaggcgggcagtgcatccagaagcgtttatattctgagcgccagttcagctttcaaaaaga gtgctgcccataaaaagccttccaccctcctgtctgctttagaaggaccctgagccccaggcgccagccacaggactctg ctgcagaggggggttgtgtacagatagtaggctttacgcctagcttcgaaatggataacgtcctcccggtggactcagac ctctccccaaacatctccactaacacctcggaacccaatcagttcgtgcaaccagcctggcaaattgtcctttgggcagc tgcctacacggtcattgtggtgacctctgtggtgggcaacgtggtagtgatgtggatcatcttagcccacaaaagaatga ggacagtgacgaactattttctggtgaacctggccttcgcggaggcctccatggctgcattcaatacagtggtgaacttc acctatgctgtccacaacgaatggtactacggcctgttctactgcaagttccacaacttctttcccatcgccgctgtctt cgccagtatctactccatgacggctgtggcctttgataggtacatggccatcatacatcccctccagccccggctgtcag ccacagccaccaaagtggtcatctgtgtcatctgggtcctggctctcctgctggccttcccccagggctactactcaacc acagagaccatgcccagcagagtcgtgtgcatgatcgaatggccagagcatccgaacaagatttatgagaaagtgtacca catctgtgtgactgtgctgatctacttcctccccctgctggtgattggctatgcatacaccgtagtgggaatcacactat gggccagtgagatccccggggactcctctgaccgctaccacgagcaagtctctgccaagcgcaaggtggtcaaaatgatg attgtcgtggtgtgcaccttcgccatctgctggctgcccttccacatcttcttcctcctgccctacatcaacccagatct ctacctgaagaagtttatccagcaggtctacctggccatcatgtggctggccatgagctccaccatgtacaaccccatca tctactgctgcctcaatgacaggttccgtctgggcttcaagcatgccttccggtgctgccccttcatcagcgccggcgac tatgaggggctggaaatgaaatccacccggtatctccagacccagggcagtgtgtacaaagtcagccgcctggagaccac catctccacagtggtgggggcccacgaggaggagccagaggacggccccaaggccacaccctcgtccctggacctgacct ccaactgctcttcacgaagtgactccaagaccatgacagagagcttcagcttctcctccaatgtgctctcctaggccaca gggcctttggcaggtgcagcccccactgcctttgacctgcctcccttcatgcatggaaattcccttcatctggaaccatc agaaacaccctcacactgggacttgcaaaaagggtcagtatgggttagggaaaacattccatccttgagtcaaaaaatct caattcttccctatctttgccaccctcatgctgtgtgactcaaaccaaatcactgaactttgctgagcctgtaaaataaa aggtcggaccagcttttcctcaagagcccaatgcattccatttctggaagtgactttggctgcatgcgagtgctcatttc aggatg (SEQ ID NO:12002) gaaaaagccttccaccctcctgtctggctttagaaggaccctgagccccaggcgccacgacaggactctgctgcagaggg gggttgtgtacagatagtagggctttaccgcctagcttcgaaatggataacgtcctcccggtggactcagacctctcccc aaacatctccactaacacctcggaacccaatcagttcgtgcaaccagcctggcaaattgtcctttgggcagctgcctaca cggtcattgtggtgacctctgtggtgggcaacgtggtagtgatgtggatcatcttagcccacaaaagaatgaggacagtg acgaactattttctggtgaacctggccttcgcggaggcctccatggctgcattcaatacagtggtgaacttcacctatgc tgtccacaacgaatggtactacggcctgttctactgcaagttccacaacttcttccccatcgccgctgtcttcgccagta tctactccatgacggctgtggcctttgataggtacatggccatcatacatcccctccagccccggctgtcagccacagcc accaaagtggtcatctgtgtcatctgggtcctggctctcctgctggccttcccccagggctactactcaaccacagagac catgcccagcagagtcgtgtgcatgatcgaatggccagagcatccgaacaagatttatgagaaagtgtaccacatctgtg tgactgtgctgatctacttcctccccctgctggtgattggctatgcatacaccgtagtgggaatcacactatgggccagt gagatccccggggactcctctgaccgctaccacgagcaagtctctgccaagcgcaaggtggtcaaaatgatgattgtcgt ggtgtgcaccttcgccatctgctggctgcccttccacatcttcttcctcctgccctacatcaacccagatctctacctga agaagtttatccagcaggtctacctggccatcatgtggctggccatgagctccaccatgtacaaccccatcatctactgc tgcctcaatgacaggtgaggatcccaaccccatgagctctccaggggccacaagaccatctacatacacagtggccaagc ggcatcctaaatgagtaaacccagctgtgagacaagagggacaagtggggactgcagctaacttatcatcacacaactca gcctggctgattatcaccatccaggaatgggagcccggagtagactgattttctttttttcttttcca (SEQ ID Nθ:1200₃) atgctgagaaaggtagctgccaaaccttgactgcaataacaataacaaaaattaaaaacctaaaataataagtatatcat actgacctttcctgtttaccttgctgtaggtaccacatctgtgtgactgtgctgatctacttcctccccctgctggtgat tggctatgcatacaccgtagtgggaatcacactatgggccagtgagatccccggggactcctctgaccgctaccacgagc aagtctctgccaagcgcaaggtgagcaggggacaggcagaactaacccaccctggcacagacaacaggctgtcgagaagg gatggcacacttgtgagccccagaggcagctagcacaaaatatccccaggtat (SEQ ID NO: 12004) ggatccaatttttgcccggcataagtgtatagtaaatttcccagccttaaagcacttcccgagagatgctttgagcgctc gcggtaccagtgcgtaaacgccgctccccggctggcgcgggtgtgcgccaactccaacctgcgcgcaagtctgccggtgc gcgctccagtcccacagctccgagtccccgcagtgaaaggagggggcggtgcaccggggtagatgggcccctgaggactc ccggggttcagttttccgcggctgccaagagggccaagttggacagtggcagggtcctgaagcagatcagcaacaaccgc aagtgctccagccccaggtcctcagacacggaggaaaacgacaagaggcggacacacaacgtcttggaacgtcagaggag gaacgagctgaagcgcagcttttttgccctgcgtgaccagatccctgaattggaaaacaacgaaaaggcccccaaggtag tgatcctcaaaaaagccaccgcctacatcctgtccattcaagcagacgagcacaagctcacctctgaaaaggacttattg aggaaacgacgagaacagttgaaacacaaactcgaacagcttcgaaactctggtgcataaactgacctaactcgaggagg agctggaatctctcgtgagagtaaggagaacggttccttctgacagaactgatgcgctggaattaaaatgcatgctcaaa gcctaacctcacaaccttggctggggctttgggactgtaagcttagagactgtcacttcccaggtgaatcagctagccag gtaactgagctagatattttgtgggggtgtttcctaaacacagcctcaggaaagttgttttcgggacacctggaccaggg agtcgtcgcctctggcttctcggtagctggagcgcggcccggagcgcggcgctggcacatcgcccccacacatgaccgtt tcccattgccacaggcaagccgcctctgcagagctgtctcagggctctgggcttcattccctggaagttgattgtcctcc actccagctgtttcccaaatccttccttcctcccagcacccctcgtgcaacgacgattccagctgcggaccgcatctgtg tcagttacttccaagccacctactgccccctcgcggagtgcgtggggctcccggctcgcagactcccacggcaagtagca agcagcaaaaggcgtggtagctgcggcggtggaatgagacagttgtcaacagctggcgcacgtgccgccgtgcgcaccgg gactggcgagtacgcagcccaggtactgccccttcccagtgacgtctctgcagggggttataaaagcctcgtgcgcagct aactcgcgagctgagcaacccgaaccgagaggtgcccgcgaaactgcaggcggcggcagcggcagcaaaagagaaggaaa aatctccagctggatacgaagctccagaatcctggccataggctcagaacttttacaggtcgcgctgcaatgggccccca cttcgctcctaagtcctcacgcagcacagggctttgcctttccctgcggaggaaggagaaataggagttgcaggcagcag caggtgcataaatgcgggggatctcttgcttcctagaactgtgaccggtggaatttctttccctttttcagtttaccgca agagagatgctgtctccagacttctgaactcaaacgtctcctgaagcttgaaagtggaggaattcagagccaccgcgggc aggcgggcagtgcatccagaagcgtttatattctgagcgccagttcagctttcaaaaagagtgctgcccagaaaaagcct tccaccctcctgtctggctttagaaggaccctgagccccaggcgccagccacaggactctgctgcagaggggggttgtgt acagatagtagggctttaccgcctagcttcgaaatggataacgtcctcccggtggactcagacctctccccaaacatctc cactaacacctcggaacccaatcagttcgtgcaaccagcctggcaaattgtcctttgggcagctgcctacacggtcattg tggtgacctctgtggtgggcaacgtggtagtgatgtggatcatcttagcccacaaaagaatgaggacagtgacgaactat tttctggtgaacctggccttcgcggaggcctccatggctgcattcaatacagtggtgaacttcacctatgctgtccacaa cgaatggtactacggcctgttctactgcaagttccacaacttcttccccatcgccgctgtcttcgccagtatctactcca tgacggctgtggcctttgataggtgagattagcctttgtgaaaaggcgagaaagtgctcatagaggaccatggcattgct gtgaggtttggaactgggtggggtatgggtcaagtggaagattggccactctgagggtttttttactgatca (SEQ ID NO: 12005) agaatatggaaaaggaattggaaaataattgtacaaatca caggaatcaaagggtttctatgaattttcttattggcag gaaaaatatggaatctctgatacagattttggtgaccagatcagaactttgttctttcttctctgttccaggtacatggc catcatacatcccctccagccccggctgtcagccacagccaccaaagtggtcatctgtgtcatctgggtcctggctctcc tgctggccttcccccagggctactactcaaccacagagaccatgcccagcagagtcgtgtgcatgatcgaatggccagag catccgaacaagatttatgagaaagtgtgagtagagatgactccccatgccaaagaaacgatggtgcaggctgccttcct ggccccttcttgctctttctttctttccatattcttttgttggtacagatttaatgtgtatctgcaagcatttctcacat ataccctcatatcaggttgatatgtccacagttgtcaggggactatagtatcccaaatactattctgagcattgaaagat aatttttgaagtgtaagatctagatcctgttata (SEQ ID NO: 12006) gagggggatgtgctggtggtctcacctgtctcaccctcttgccaggtggtcaaaatgatgattgtcgtggtgtgcacctt cgccatctgctggctgcccttccacatcttcttcctcctgccctacatcaacccagatctctacctgaagaagtttatcc agcaggtctacctggccatcatgtggctggccatgagctccaccatgtacaaccccatcatctactgctgcctcaatgac aggtgaggatcccaaccccatgagctctccaggggccacaagaccatctacatacacagtggccaagcggcatctaaatg agtaaacccagctgtgagacaagagggacaagtggggactgcagctaactt (SEQ ID NO: 12007) ccgtcccaaaggtcacctcttcatctgctcgctctccaggttccgtctgggcttcaagcatgccttccggtgctgcccct tcatcagcgccggcgactatgaggggctggaaatgaaatccacccggtatctccagacccagggcagtgtgtacaaagtc agccgcctggagaccaccatctccacagtggtgggggcccacgaggaggagccagaggacggccccaaggccacaccctc gtccctggacctgacctccaactgctcttcacgaagtgactccaagaccatgacagagagcttcagcttctcctccaatg tgctctcctaggccacagggcctttggcaggtgcagcccccactgcctttgacctgcctcccttcatgcatggaaattcc cttcatctggaaccatcagaaacaccctcacactgggacttgcaaaaagggtcagtatgggttagggaaaacattccatc cttgagtcaaaaaatctcaattcttccctatctttgccaccctcatgctgtgtgactcaaaccaaatcactgaactttgc tgagcctgtaaaataaaaggtcggaccagcttttcccaaaagcccattcattccattctggaagtgactttggctgcatg cgagtgctcatttcaggatgaattctgcagcacagctgcggacccggaagactcattttcctggagccccgtgttacttc aataaagttatctcagattagcctcctgcagctggaggctcctatcaccccagcctacgcttgacagggtgaacaaaaga aggcaccacataacatctaaatgaaaaatttagccctgtcttctaagcatctgtgaaaagaaacatatgtattccccttt ttggcatctcagtatttcagtacatttatacatcatgagattgagaacctcgggcttccacattatgtccccggtgactg tcctgagcagccgacgcaagcagaatatgtccactgatacctgctagttctcttacagaccaggaattgggagacttgca ctacatttaatgtgtagttgaccctcttttcctacttgtaaacaaggggactgaactagataatctaag gt ccttcga atcttaacatcccgtggttcaaggattgtatgagttttttgtttgttttacaaaaaaaaacaaaacgaagaataaaagaa tagaaaagaataggagcagtgagtcttgtaactaatacccagttcctggagatgtagcaactgctaaggccatctgtaac tatccatctcagacattctccgatttatcttaaaatcctgagtacattccttctcatggaaggttttggcttttgacaga gcagaggacttcatgccaaggcctgcatccatccagctttagcaggcagaatttcatagctgcagaacactgtcagagaa gacaaatgtgggctccctgctttaaccttttgggtattttagggtgggggccctaaccttcattcttagttttacactag catcgtgctcatatgtgcgacaagcaagaaggctgcactttgcagctgcacttctgggaagagggcatcttgcatcttcc cttcagactctctgaatgtctcctccctgctccatggctttgccagcttcctgtctctaaggggtagaatgactcatcaa ccctaaaggacagtcagtcttccaagagccatgaactgaatgctttatatcctaatttagatttagagtttccagaaggt gagcatgcagttttgttttgtttttttttctgtctcccaaatctgtgttttttccagatatggctggaagcagaagcttc atgtaacatccatgaatgtcctcctggtagtttgcataatggatgcacatgtgccgcatccataacattaaggggagaat aatgcatggtttacagcctttgccagccctgctggctctaattctaccagggcatccacaggcctgggggaagaagaaac agtataagccagaaaacctcaagaactacattctctaaagcagcatggaaagttttaaataaactaagtgaagccagatc attgcagatatataaatggaagacaaaatttagaagcaacaaaagttagtgccctaagcattagtcatacttccaataga gaatcttgctgtgtatggattactcactttggaagaatgtaaagagctaacatgattatgagaagtacctgagaagatgg tgtcaagaagttggggacaccccatctatggaagagaaggttagagttgagctcaacgaggattaactgagtgcctcctc tggactttgccctgaactgggaacacacagcccctgcagctcttgaagagcctaccttattggccatcactaactaactc accagtcctagtgagtctaagctgcccagcagtcttggaggcatctgagaggacagattctccacagaattctaaaaacc cacactcaacatgggcagtcaagcaaagactgggacctttggagagcctctggaatgagagttctctggggtacttccaa agggagctggcagtcagtccaggggacctaaaggaatttggttgaacagtatcatctctgtgcatagtaagagggaatgt tgggtggtccgggcagtttccaatatggcaaagcatctgcttggacagtgccagcaagccttcctctgacccagtctcca atgtccactaacttataaaaatgtcatcaactcccacatgtgagaaacaccatgatttgtactgtgcatgggtcacattc ttattctagaaatgcatcaccctgtgtttatccaagtgtgtttacttggtgtaatgtccagtagtaatagaatatgaaat atcaaggaaccatctttgttacgtgacttccaaaatgtgagatctcattgctgtcactgtgatatttgtattgtgtgaat ctcttcctcctcttcctcctcatgctttctcagggaggagccctgatgtatatcatgaactcacagttcctagaccacag taattgaggggcggtgggggggcctttatcggagaagctagagaacaagagtccttctcctccttatcccccaacaggac actaagagacaaggactgagtggaatcctggagaaaggggactcaggaactgacctcattggcctgatttgtgaggagag gagtataagtggagaggggccattcctgaggtttccgtgttttccagcctggtctcctggaaagaatctttatacagaaa taaagtatgtgtttcactctctcgtgcctctgtctcttctctaggggtcctaaacatcctataggatgctaaatgggatg gtactagaaaccctaataacttgcatagctagaaggatggaatcaatgttcagtaaactcttgactctgtgatgaaatgg gttgggaagatgtgggaacagttcccaggttgagatctgggaagggaggtgggattatgcgaaatcacagtgatgttgcc tatgaataaagctgtgtcaggatgcagacacaacagagttataagcacaagggagttttcgtaggacaggaggttggggg gaataacatctgagaaagacaaaggggaaagaaagcagaagtactcagggacagccttcagaccaccatgccaatctgac acctgggaaaaaaggggtggttaggaagagcctcagactgtggtgcagctcccagcccaacacgtgcaaagattgcccag agagacattgcacgttaacagaatggccaggcctgatgccctgccgtgctcagccgctggctggggctctctagggaaag tgttctgtgtttgaacaccatggtggatgctgaagccctgcagctggaggctgtcagccaagtgccctgcagttcttcct aaagaggga (SEQ ID NO: 12008) gaaaaagccttccaccctcctgtctggctttagaaggaccctgagccccaggcgccacgacaggactctgctgcagaggg gggttgtgtacagatagtagggctttaccgcctagcttcgaaatggataacgtcctcccggtggactcagacctctcccc aaacatctccactaacacctcggaacccaatcagttcgtgcaaccagcctggcaaattgtcctttgggcagctgcctaca cggtcattgtggtgacctctgtggtgggcaacgtggtagtgatgtggatcatcttagcccacaaaagaatgaggacagtg acgaactattttctggtgaacctggccttcgcggaggcctccatggctgcattcaatacagtggtgaacttcacctatgc tgtccacaacgaatggtactacggcctgttctactgcaagttccacaacttcttccccatcgccgctgtcttcgccagta tctactccatgacggctgtggcctttgataggtacatggccatcatacatcccctccagccccggctgtcagccacagcc accaaagtggtcatctgtgtcatctgggtcctggctctcctgctggccttcccccagggctactactcaaccacagagac catgcccagcagagtcgtgtgcatgatcgaatggccagagcatccgaacaagatttatgagaaagtgtaccacatctgtg tgactgtgctgatctacttcctccccctgctggtgattggctatgcatacaccgtagtgggaatcacactatgggccagt gagatccccggggactcctctgaccgctaccacgagcaagtctctgccaagcgcaaggtggtcaaaatgatgattgtcgt ggtgtgcaccttcgccatctgctggctgcccttccacatcttcttcctcctgccctacatcaacccagatctctacctga agaagtttatccagcaggtctacctggccatcatgtggctggccatgagctccaccatgtacaaccccatcatctactgc tgcctcaatgacaggttccgtctgggcttcaagcatgccttccggtgctgccccttcatcagcgccggcgactatgaggg gctggaaatgaaatccacccggtatctccagacccagggcagtgtgtacaaagtcagccgcctggagaccaccatctcca cagtggtgggggcccacgaggaggagccagaggacggccccaaggccacaccctcgtccctggacctgacctccaactgc tcttcacgaagtgactccaagaccatgacagagagcttcagcttctcctccaatgtgctctcctaggccacagggccttt ggcaggtgcagcccccactgcctttgacctgcctcccttcatgcatggaaattcccttcatctggaaccatcagaaacac cctcacactgggacttgcaaaaagggtcagtatgggttagggaaaacattccatccttgagtcaaaaaatctcaattctt ccctatctttgccaccctcatgctgtgtgactcaaaccaaatcactgaactttgctgagcctgtaaaataaaaggtcgga ccagcttttcccaaaagcccattcattccattctggaagtgactttggctgcatgcgagtgctcatttcaggataattca gagccaccgcgggcaggcgggcagtgcatccagaagcgtttatattctgagcgccagttcagctttcaaaaagagtgctg cccataaaaagccttccaccctcctgtctgctttagaaggaccctgagccccaggcgccagccacaggactctgctgcag aggggggttgtgtacagatagtaggctttacgcctagcttcgaaatggataacgtcctcccggtggactcagacctctcc ccaaacatctccactaacacctcggaacccaatcagttcgtgcaaccagcctggcaaattgtcctttgggcagctgccta cacggtcattgtggtgacctctgtggtgggcaacgtggtagtgatgtggatcatcttagcccacaaaagaatgaggacag tgacgaactattttctggtgaacctggccttcgcggaggcctccatggctgcattcaatacagtggtgaacttcacctat gctgtccacaacgaatgg actacggcctgttctactgcaagttccacaacttctttcccatcgccgctgtcttcgccag tatctactccatgacggctgtggcctttgataggtacatggccatcatacatcccctccagccccggctgtcagccacag ccaccaaagtggtcatctgtgtcatctgggtcctggctctcctgctggccttcccccagggctactactcaaccacagag accatgcccagcagagtcgtgtgcatgatcgaatggccagagcatccgaacaagatttatgagaaagtgtaccacatctg tgtgactgtgctgatctacttcctccccctgctggtgattggctatgcatacaccgtagtgggaatcacactatgggcca gtgagatccccggggactcctctgaccgctaccacgagcaagtctctgccaagcgcaaggtggtcaaaatgatgattgtc gtggtgtgcaccttcgccatctgctggctgcccttccacatcttcttcctcctgccctacatcaacccagatctctacct gaagaagtttatccagcaggtctacctggccatcatgtggctggccatgagctccaccatgtacaaccccatcatctact gctgcctcaatgacaggttccgtctgggcttcaagcatgccttccggtgctgccccttcatcagcgccggcgactatgag gggctggaaatgaaatccacccggtatctccagacccagggcagtgtgtacaaagtcagccgcctggagaccaccatctc cacagtggtgggggcccacgaggaggagccagaggacggccccaaggccacaccctcgtccctggacctgacctccaact gctcttcacgaagtgactccaagaccatgacagagagcttcagcttctcctccaatgtgctctcctaggccacagggcct ttggcaggtgcagcccccactgcctttgacctgcctcccttcatgcatggaaattcccttcatctggaaccatcagaaac accctcacactgggacttgcaaaaagggtcagtatgggttagggaaaacattccatccttgagtcaaaaaatctcaattc ttccctatctttgccaccctcatgctgtgtgactcaaaccaaatcactgaactttgctgagcctgtaaaataaaaggtcg gaccagcttttcctcaagagcccaatgcattccatttctggaagtgactttggctgcatgcgagtgctcatttcaggatg gaaaaagccttccaccctcctgtctggctttagaaggaccctgagccccaggcgccacgacaggactctgctgcagaggg gggttgtgtacagatagtagggctttaccgcctagcttcgaaatggataacgtcctcccggtggactcagacctctcccc aaacatctccactaacacctcggaacccaatcagttcgtgcaaccagcctggcaaattgtcctttgggcagctgcctaca cggtcattgtggtgacctctgtggtgggcaacgtggtagtgatgtggatcatcttagcccacaaaagaatgaggacagtg acgaactattttctggtgaacctggccttcgcggaggcctccatggctgcattcaatacagtggtgaacttcacctatgc tgtccacaacgaatggtactacggcctgttctactgcaagttccacaacttcttccccatcgccgctgtcttcgccagta tctactccatgacggctgtggcctttgataggtacatggccatcatacatcccctccagccccggctgtcagccacagcc accaaagtggtcatctgtgtcatctgggtcctggctctcctgctggccttcccccagggctactactcaaccacagagac catgcccagcagagtcgtgtgcatgatcgaatggccagagcatccgaacaagatttatgagaaagtgtaccacatctgtg tgactgtgctgatctacttcctccccctgctggtgattggctatgcatacaccgtagtgggaatcacactatgggccagt gagatccccggggactcctctgaccgctaccacgagcaagtctctgccaagcgcaaggtggtcaaaatgatgattgtcgt ggtgtgcaccttcgccatctgctggctgcccttccacatcttcttcctcctgccctacatcaacccagatctctacctga agaagtttatccagcaggtctacctggccatcatgtggctggccatgagctccaccatgtacaaccccatcatctactgc tgcctcaatgacaggtgaggatcccaaccccatgagctctccaggggccacaagaccatctacatacacagtggccaagc ggcatcctaaatgagtaaacccagctgtgagacaagagggacaagtggggactgcagctaacttatcatcacacaactca gcctggctgattatcaccatccaggaatgggagcccggagtagactgattttctttttttcttttccaatgctgagaaag gtagctgccaaaccttgactgcaataacaataacaaaaattaaaaacctaaaataataagtatatcatactgacctttcc tgtttaccttgctgtaggtaccacatctgtgtgactgtgctgatctacttcctccccctgctggtgattggctatgcata caccgtagtgggaatcacactatgggccagtgagatccccggggactcctctgaccgctaccacgagcaagtctctgcca agcgcaaggtgagcaggggacaggcagaactaacccaccctggcacagacaacaggctgtcgagaagggatggcacactt gtgagccccagaggcagctagcacaaaatatccccaggtatggatccaatttttgcccggcataagtgtatagtaaattt cccagccttaaagcacttcccgagagatgctttgagcgctcgcggtaccagtgcgtaaacgccgctccccggctggcgcg ggtgtgcgccaactccaacctgcgcgcaagtctgccgg^'tgcgcgctccagtcccacagctccgagtccccgcagtgaaag gagggggcggtgcaccggggtagatgggcccctgaggactcccggggttcagttttccgcggctgccaagagggccaagt tggacagtggcagggtcctgaagcagatcagcaacaaccgcaagtgctccagccccaggtcctcagacacggaggaaaac gacaagaggcggacacacaacgtcttggaacgtcagaggaggaacgagctgaagcgcagcttttttgccctgcgtgacca gatccctgaattggaaaacaacgaaaaggcccccaaggtagtgatcctcaaaaaagccaccgcctacatcctgtccattc aagcagacgagcacaagctcacctctgaaaaggacttattgaggaaacgacgagaacagttgaaacacaaactcgaacag cttcgaaactctggtgcataaactgacctaactcgaggaggagctggaatctctcgtgagagtaaggagaacggttcctt ctgacagaactgatgcgctggaattaaaatgcatgctcaaagcctaacctcacaaccttggctggggctttgggactgta agcttagagactgtcacttcccaggtgaatcagctagccaggtaactgagctagatattttgtgggggtgtttcctaaac acagcctcaggaaagttgttttcgggacacctggaccagggagtcgtcgcctctggcttctcggtagctggagcgcggcc cggagcgcggcgctggcacatcgcccccacacatgaccgtttcccattgccacaggcaagccgcctctgcagagctgtct cagggctctgggcttcattccctggaagttgattgtcctccactccagctgtttcccaaatccttccttcctcccagcac ccctcgtgcaacgacgattccagctgcggaccgcatctgtgtcagttacttccaagccacctactgccccctcgcggagt gcgtggggctcccggctcgcagactcccacggcaagtagcaagcagcaaaaggcgtggtagctgcggcggtggaatgaga cagttgtcaacagctggcgcacgtgccgccgtgcgcaccgggactggcgagtacgcagcccaggtactgccccttcccag tgacgtctctgcagggggttataaaagcctcgtgcgcagctaactcgcgagctgagcaacccgaaccgagaggtgcccgc gaaactgcaggcggcggcagcggcagcaaaagagaaggaaaaatctccagctggatacgaagctccagaatcctggccat aggctcagaacttttacaggtcgcgctgcaatgggcccccacttcgctcctaagtcctcacgcagcacagggctttgcct ttccctgcggaggaaggagaaataggagttgcaggcagcagcaggtgcataaatgcgggggatctcttgcttcctagaac tgtgaccggtggaatttctttccctttttcagtttaccgcaagagagatgctgtctccagacttctgaactcaaacgtct cctgaagcttgaaagtggaggaattcagagccaccgcgggcaggcgggcagtgcatccagaagcgtttatattctgagcg ccagttcagctttcaaaaagagtgctgcccagaaaaagccttccaccctcctgtctggctttagaaggaccctgagcccc aggcgccagccacaggactctgctgcagaggggggttgtgtacagatagtagggctttaccgcctagcttcgaaatggat aacgtcctcccggtggactcagacctctccccaaacatctccactaacacctcggaacccaatcagttcgtgcaaccagc ctggcaaattgtcctttgggcagctgcctacacggtcattgtggtgacctctgtggtgggcaacgtggtagtgatgtgga tcatcttagcccacaaaagaatgaggacagtgacgaactattttctggtgaacctggccttcgcggaggcctccatggct gcattcaatacagtggtgaacttcacctatgctgtccacaacgaatggtactacggcctgttctactgcaagttccacaa cttcttccccatcgccgctgtcttcgccagtatctactccatgacggctgtggcctttgataggtgagattagcctttgt gaaaaggcgagaaagtgctcatagaggaccatggcattgctgtgaggtttggaactgggtggggtatgggtcaagtggaa gattggccactctgagggtttttttactgatcaagaatatggaaaaggaattggaaaataattgtacaaatcatcaggaa tcaaagggtttctatgaattttcttattggcaggaaaaatatggaatctctgatacagattttggtgaccagatcagaac tttgttctttcttctctgttccaggtacatggccatcatacatcccctccagccccggctgtcagccacagccaccaaag tggtcatctgtgtcatctgggtcctggctctcctgctggccttcccccagggctactactcaaccacagagaccatgccc agcagagtcgtgtgcatgatcgaatggccagagcatccgaacaagatttatgagaaagtgtgagtagagatgactcccca tgccaaagaaacgatggtgcaggctgccttcctggccccttcttgctctttctttctttccatattcttttgttggtaca gatttaatgtgtatctgcaagcatttctcacatataccctcatatcaggttgatatgtccacagttgtcaggggactata gtatcccaaatactattctgagcattgaaagataatttttgaagtgtaagatctagatcctgttatagagggggatgtgc tggtggtctcacctgtctcaccctcttgccaggtggtcaaaatgatgattgtcgtggtgtgcaccttcgccatctgctgg ctgcccttccacatcttcttcctcctgccctacatcaacccagatctctacctgaagaagtttatccagcaggtctacct ggccatcatgtggctggccatgagctccaccatgtacaaccccatcatctactgctgcctcaatgacaggtgaggatccc aaccccatgagctctccaggggccacaagaccatctacatacacagtggccaagcggcatctaaatgagtaaacccagct gtgagacaagagggacaagtggggactgcagctaacttccgtcccaaaggtcacctcttcatctgctcgctctccaggtt ccgtctgggcttcaagcatgccttccggtgctgccccttcatcagcgccggcgactatgaggggctggaaatgaaatcca cccggtatctccagacccagggcagtgtgtacaaagtcagccgcctggagaccaccatctccacagtggtgggggcccac gaggaggagccagaggacggccccaaggccacaccctcgtccctggacctgacctccaactgctcttcacgaagtgactc caagaccatgacagagagcttcagcttctcctccaatgtgctctcctaggccacagggcctttggcaggtgcagccccca ctgcctttgacctgcctcccttcatgcatggaaattcccttcatctggaaccatcagaaacaccctcacactgggacttg caaaaagggtcagtatgggttagggaaaacattccatccttgagtcaaaaaatctcaattcttccctatctttgccaccc tcatgctgtgtgactcaaaccaaatcactgaactttgctgagcctgtaaaataaaaggtcggaccagcttttcccaaaag cccattcattccattctggaagtgactttggctgcatgcgagtgctcatttcaggatgaattctgcagcacagctgcgga cccggaagactcattttcctggagccccgtgttacttcaataaagttatctcagattagcctcctgcagctggaggctcc tatcaccccagcctacgcttgacagggtgaacaaaagaaggcaccacataacatctaaatgaaaaatttagccctgtctt ctaagcatctgtgaaaagaaacatatgtattcccctttttggcatctcagtatttcagtacatttatacatcatgagatt gagaacctcgggcttccacattatgtccccggtgactgtcctgagcagccgacgcaagcagaatatgtccactgatacct gctagttctcttacagaccaggaattgggagacttgcactacatttaatgtgtagttgaccctcttttcctacttgtaaa caaggggactgaactagataatctaagtgttccttcgaatcttaacatcccgtggttcaaggattgtatgagttttttgt ttgttttacaaaaaaaaacaaaacgaagaataaaagaatagaaaagaataggagcagtgagtcttgtaactaatacccag ttcctggagatgtagcaactgctaaggccatctgtaactatccatctcagacattctccgatttatcttaaaatcctgag tacattccttctcatggaaggttttggcttttgacagagcagaggacttcatgccaaggcctgcatccatccagctttag caggcagaatttcatagctgcagaacactgtcagagaagacaaatgtgggctccctgctttaaccttttgggtattttag ggtgggggccctaaccttcattcttagttttacactagcatcgtgctcatatgtgcgacaagcaagaaggctgcactttg cagctgcacttctgggaagagggcatcttgcatcttcccttcagactctctgaatgtctcctccctgctccatggctttg ccagcttcctgtctctaaggggtagaatgactcatcaaccctaaaggacagtcagtcttccaagagccatgaactgaatg ctttatatcctaatttagatttagagtttccagaaggtgagcatgcagttttgttttgtttttttttctgtctcccaaat ctgtgttttttccagatatggctggaagcagaagcttcatgtaacatccatgaatgtcctcctggtagtttgcataatgg atgcacatgtgccgcatccataacattaaggggagaataatgcatggtttacagcctttgccagccctgctggctctaat tctaccagggcatccacaggcctgggggaagaagaaacagtataagccagaaaacctcaagaactacattctctaaagca gcatggaaagttttaaataaactaagtgaagccagatcattgcagatatataaatggaagacaaaatttagaagcaacaa aagttagtgccctaagcattagtcatacttccaatagagaatcttgctgtgtatggattactcactttggaagaatgtaa agagctaacatgattatgagaagtacctgagaagatggtgtcaagaagttggggacaccccatctatggaagagaaggtt agagttgagctcaacgaggattaactgagtgcctcctctggactttgccctgaactgggaacacacagcccctgcagctc ttgaagagcctaccttattggccatcactaactaactcaccagtcctagtgagtctaagctgcccagcagtcttggaggc atctgagaggacagattctccacagaattctaaaaacccacactcaacatgggcagtcaagcaaagactgggacctttgg agagcctctggaatgagagttctctggggtacttccaaagggagctggcagtcagtccaggggacctaaaggaatttggt tgaacagtatcatctctgtgcatagtaagagggaatgttgggtggtccgggcagtttccaatatggcaaagcatctgctt ggacagtgccagcaagccttcctctgacccagtctccaatgtccactaacttataaaaatgtcatcaactcccacatgtg agaaacaccatgatttgtactgtgcatgggtcacattcttattctagaaatgcatcaccctgtgtttatccaagtgtgtt tacttggtgtaatgtccagtagtaatagaatatgaaatatcaaggaaccatctttgttacgtgacttccaaaatgtgaga tctcattgctgtcactgtgatatttgtattgtgtgaatctcttcctcctcttcctcctcatgctttctcagggaggagcc ctgatgtatatcatgaactcacagttcctagaccacagtaattgaggggcggtgggggggcctttatcggagaagctaga gaacaagagtccttctcctccttatcccccaacaggacactaagagacaaggactgagtggaatcctggagaaaggggac tcaggaactgacctcattggcctgatttgtgaggagaggagtataagtggagaggggccattcctgaggtttccgtgttt tccagcctggtctcctggaaagaatctttatacagaaataaagtatgtgtttcactctctcgtgcctctgtctcttctct aggggtcctaaacatcctataggatgctaaatgggatggtactagaaaccctaataacttgcatagctagaaggatggaa tcaatgttcagtaaactcttgactctgtgatgaaatgggttgggaagatgtgggaacagttcccaggttgagatctggga agggaggtgggattatgcgaaatcacagtgatgttgcctatgaataaagctgtgtcaggatgcagacacaacagagttat aagcacaagggagttttcgtaggacaggaggttggggggaataacatctgagaaagacaaaggggaaagaaagcagaagt actcagggacagccttcagaccaccatgccaatctgacacctgggaaaaaaggggtggttaggaagagcctcagactgtg gtgcagctcccagcccaacacgtgcaaagattgcccagagagacattgcacgttaacagaatggccaggcctgatgccct gccgtgctcagccgctggctggggctctctagggaaagtgttctgtgtttgaacaccatggtggatgctgaagccctgca gctggaggctgtcagccaagtgccctgcagttcttcctaaagaggga (SEQ ID NO: 12009) gggtctcaaggaatctttattctgcgtcttcattctgaactggatggaaccttcctgagcgcagagtcctttccactgtg aattatgggtttgttatcgtttttgttcgttgctggttgtacgtgacgggagttcagctttttgctgcgggacggcagag ataggatgcggggcttcctgagaggcgccggggcagggccgcacaggtccatccacctcccctgggaccccagccctgca gcagccccaggggagcggccggggatcggggcggggtgcccaggacgcgccctgattggccCagtgttagccaatcaagg ctctcgcatccccatggtgctgattggtccgcctcccaggcctgacccaatcggagcattcctaggaggagcggccccag agcgcctgactcgggggtcccagagccctctgcacaccacagccccggtgtccccgtgtgtccctgggttctcccagccc tggtgtcccctgagtctcttcttcaccgtcagccctggtgtctcccgtgtccctgccacaccctcatccctggtgtcccc cgtcaccccatcccctcacctcctgggctcctgaaggtcccatcttgtgggcctcattcatggaaccaggacggggcagg tggaggcctctggggagtttgtccagagaatggaggagaagcagggtcatgagcaggagcggtctgggccacccctgcct gtcccccggggggtgcagcccggaaggagtccagatggatatggccccgcagtgcagagtcagccccaaaccaggctggt cccaggcagggtgggggcaggaggagccccggagtggccctgtgttgggggtcggggggcaggcagggggtcctggggct cagaagcggaggaggtgggctggaggccccagtgaccaacaggcccacgggagtcgggaggtggggtggacggacctgca gggacagtgtcagcgctgaatgggatggagagcacagggagctggggccggggatgagaccatggggagctggggctggg gctgggactagtccatggggagctggggctgaagttgggggtgagtccatggggagctgggctgggcctcctggggttgc acctgcactcctctctgctcttccctctgcgtatgaagctcagatcccatgataaggaggcacctgcagaccaggggacc tgcacggacagccccagaggtggacattgaggactcgtaggaggacttgggtctcatacggcgggtggggagcagggccc cttcctggctgaggacacttggtgctgtcccctctcaaggctgtttccccatctgacaaaggggtctcatgtgagccccc aaccaagtgagtcgaggagggctggccccacccccgtggatttggagtccgtaggaggggtgtcacccgtcacgtcccca ccccgtgggcaccttcccgtctcttggagcgtggcccatggacatgagttcctcacccgtgtccctcttggggaaacagg tttcaggagcgacgggtcttgtagcctggggcagccaggccacctgggtgcagctatgcctgaaggcctcctggcaccga gacaggggcaggagcagatcccaccagcgggaaggtggtgcgttctgatgctgggatccaccagctgacaggtggagctg cgagcctccagtgctcagccctcggcggggcctgcctggcagccccacacacagagggcatcggggtggcgggggcacgt gttacacgggggccctgggtctgagtcatccacttcctccgagtctggatgggaggacccagcgcccctcctccgccccc tcctgatctggaaggataaatggggaggggagagcccgctgggtagaaggaacagggagtggccagggtaagtccctact ctcagagaccctgacatcagtgtcacctggagcagagtggcccagcctcagactcagagcaccaagacccaggcccgcag gcctggacccaccccggtccccccgtcccagctccattcttcaccccacaatctgtagcccccagccctgccctgtgagg cccggccaggcccacgatgctcctccttgctccccagatgctgagcctgctgctgctggcgctgcccgtcctggcgagcc cggcctacgcggcccctggtgagtcccagccggggtccaccctgcccctcaccacattccacaggtcagggcctgggtgg gttctggggaggctgggctggcccccacacagggaagggctgggcccaggcgtggggctgcttcctggtcctgacctggc acctgccccagccccagtccaggccctgcagcaagcgggtatcgtcgggggtcaggaggcccccaggagcaagtggccct ggcaggtgagcctgagagtccgcgaccgatactggatgcacttctgtgggggctccctcatccacccccagtgggtgctg accgcggcgcactgcctgggaccgtgagtctcccagggcctggaggggtgggcaagggctggatgtgagccctggctccc gggtgctcctgggggctgcccagggccctgagtgggatcctccgctgcccagggacgtcaaggatctggccaccctcagg gtgcaactgcgggagcagcacctctactaccaggaccagctgctgccggtcagcaggatca cgtgcacccacagttcta catcatccagactggagcggatatcgccctgctggagctggaggagcccgtgaacatctccagccgcgtccacacggtca tgctgccccctgcctcggagaccttccccccggggatgccgtgctgggtcactggctggggcgatgtggacaatgatggt gggtctggggacagtgggaggtggggccagggtcttagccacagcccagcccctgggctccaggtgggggttgcccggcc ccctcctcaggctgcaccctcttccccacctgcagagcccctcccaccgccatttcccctgaagcaggtgaaggtcccca taatggaaaaccacatttgtgacgcaaaataccaccttggcgcctacacgggagacgacgtccgcatcatccgtgacgac atgctgtgtgccgggaacacccggagggactcatgccaggtgggccccgcgtgtcccccgccccccgcaccccaaccccc actcccaggcctgttcggcgagcgctgacctctgaccttcccagggcgactctggagggcccctggtgtgcaaggtgaat ggcacctggctacaggcgggcgtggtcagctgggacgagggctgtgcccagcccaaccggcctggcatctacacccgtgt cacctactacttggactggatccaccactatgtccccaaaaagccgtgagtcaggcctggggtgtccacctgggtcactg gagagccagcccctcctgtccaaaacaccactgcttcctacccaggtggcgactgccccccacaccttccctgccccgtc ctgagtgccccttcctgtcctaagccccctgctctcttctgagccccttcccctgtcctgaggacccttccccatcctga gcccccttccctgtcctaagcctgacgcctgcactgggccctccggccctcccctgcccaggcagctggtggtgggcgct aatcctcctgagtgctggacctcattaaagtgcatggaaatcactggtgtgcatcgctgtgtttctggttgtggatgtca ctgggagagaaggggtccaggtgtgctgaggacacctgccacagtgcgaggtcctagccctcaaggcacagccagtcacc gtgggacggggcctcctgggcagccctggtccccggggctggcttctccccacacgatgcatccagcattcgggtcacac agagccactcgggcaactcagttgattataaaggacagccaagtccctgcaaccgggtcaagacagagaatggtcgccgg gagccccagggctgcccatcacgagcccctaccccacgcttcccacgagctcttctcccggcccctctgtccactgcttg tgctttgccctagttgtttgctttgagacaggatctcgctgtgtcatccaggctgaagtgcagtggtgtgatcagggctc actgtagccttgaactcctgggctcaagcgatcctcccatcttggcctcccatatagctgggccacaggagtgagccacc acgcccagttaatttttgtattttcagtagagatggggtttcgccatgttggccagtctggtctcgaactcctgacctca agtgatctgcccgcctcggcctcccaaagtgctgggatgacaggcgtgagccaccgcacccagcctgagtttgacatttt caaattcattttgaggtctttctctacatcaatacatgagccctccgcgtccggcgagtgttgcattttatcccgggctc ttgtttgcattttatatttgaacatgattacattcaggaatgaaatgcggggctgttctggttgaaaacaactctctaaa gaaacattcactctttccttccaactgtcagatgcagagatgtgcatttagtctctccaatctctgcaaatgacctctgt cctcacaaggggtggactcgacttccagcgccctctccagccccacgtgacctctgcctctgcagcccctgaaggcccat ccctcggctcctgttctgcaggcccagcgtcttgtctatgaagatggacctggaactcgggccctccttcctccctctgg cccatcccaccttctagggatcacagagacagcacggggtgacccccagggaacactgagcccctagaagcacttccaca cgcccactggaggttttgcggggtgggagtcggagggatgagaccccgaagggaagcaagacggcccctcaggacagggc tgccggtgtaaggaaaggtggacagcaggggccggtcactgggtggagggggagggcaggctccagccccagagcttccc aaattagatctaagatccctgggaagctcagtgaagctcagcgcagtgacactggcagatgtgagcgtcagcttcagcag gaagggtctctcaggacgtgacaggcaggctgctggccagggctgcagccacctgcgttttgactgggacgggggcacct gatccaaggtcacccacgtggctgccggcaggaggccctggttccccgtcacaagggggtgtgagggggaaggccaagtg gtggccacanggttnccaccgagagggacagtgcccaagttggccaagccaccctnggacaagaaacaatnccaagtctt nccaaggtccttggacaacaaggagaancccccccagcttgggggcnattaaccaagggccangnccccccttcccggtt c (SEQ ID Nθ:12010) tggacccaccccggtccccccgtcccagcttccattcttcaccccacaatctgtagcccccagccctgccctgtgaggcc cggccaggcccacgatgctcctccttgctccccagatgctgaatctgctgctgctggcgctgcccgtcctggcgagccgc gcctacgcggcccctggtgagtcccagccggggtccaccctgcccctcaccacattccacaggtcagggcctgggtgggt tctggggaggccgggctggcccccacacagggaagggctgggcccaggcctggggctgcttcctggtcctgacctggcac ctgccccagccccaggccaggccctgcagcgagtgggcatcgttgggggtcaggaggcccccaggagc (SEQ ID Nθ:12011) cagatcggagcggacatcgccctgctggagctggaggagccggtgaaggtctccagccacgtccacacggtcaccctgcc ccctgcctcagagaccttccccccggggatgccgtgctgggtcactggctggggcgatgtggacaatgatggtgggtctg gggacagtggaggtggggccagggtcttagccacagcccagcccctgggctccctctgggctccaggtgggggttgcccg gccccctcctgaggctgcaccctcttccccacctgcagagcgcctcccaccgccatttcctctgaagcaggtgaaggtcc ccataatggaaaaccacatttgtgacgcaaaataccaccttggcgcctacacgggagacgacgtccgcatcgtccgtgac gacatgctgtgtgccgggaacacccggagggactcatgccaggtgggccccgcgtgtcccccgccccccgcaccccaacc cccactcccaggcctgttcggcgagcgctgacctctgaccttcccagggcgactccggagggcccctggtgtgcaaggtg aatggcacctggctgcaggcgggcgtggtcagctggggcgagggctgtgcccagcccaaccggcctggcatctacacccg tgtcacctactacttggactggatccaccactatgtccccaaaaagccgtgagtcaggcctgggttggccacctgggtca ctggaggaccaacccctgctgtccaaaacaccactgcttcctacccaggtggcgactgccccccacaccttccctgcccc gtcctgagtgccccttcctgtcctaagccccctgctctcttctgagccccttcccctgtcctgaggacccttccccatcc tgagcccccttccctgtcctaagcctgacgcctgcactgggccctccggccctcccctgcccaggcagctggtggtgggc gctaatcctcctgagtgctggacctcattaaagtgcatggaaatcactggtgtgcatcgctgtgtttctggttgtggatg tcactgggagagaaggggtccaggtgtgctgaggacacctgccacagtgtgaggtcctagccctcaaggcacaagccagt caccgtgggacggggcctctgggcagccctggtccccgagctggctt (SEQ ID NO: 12012) ccaggatgctgaatctgctgctgctggcgctgcccgtcctggcgagccgcgcctacgcggcccctgccccaggccaggcc ctgcagcgagtgggcatcgttgggggtcaggaggcccccaggagcaagtggccctggcaggtgagcctgagagtccacgg cccatactggatgcacttctgcgggggctccctcatccacccccagtgggtgctgaccgcagcgcactgcgtgggaccgg ' acgtcaaggatctggccgccctcagggtgcaactgcgggagcagcacctctactaccaggaccagctgctgccggtcagc aggatcatcgtgcacccacagttctacaccgcccagatcggagcggacatcgccctgctggagctggaggagccggtgaa ggtctccagccacgtccacacggtcaccctgccccctgcctcagagaccttccccccggggatgccgtgctgggtcactg gctggggcgatgtggacaatgatgagcgcctcccaccgccatttcctctgaagcaggtgaaggtccccataatggaaaac cacatttgtgacgcaaaataccaccttggcgcctacacgggagacgacgtccgcatcgtccgtgacgacatgctgtgtgc cgggaacacccggagggactcatgccagggcgactccggagggcccctggtgtgcaaggtgaatggcacctggctgcagg cgggcgtggtcagctggggcgagggctgtgcccagcccaaccggcctggcatctacacccgtgtcacctactacttggac tggatccaccactatgtccccaaaaagccgtgagtcaggcctgggtgtgccacctgggtcactggaggaccaacccctgc tgtccaaaacaccactgcttcctacccaggtggcgactgccccccacaccttccctgccccgtcctgagtgccccttcct gtcctaagccccctgctctcttctgagccccttcccctgtcctgaggacccttccccatcctgagcccccttccctgtcc taagcctgacgcctgcactgctccggccctcccctgcccaggcagctggtggtgggcgctaatcctcctgagtgctggac ctcattaaagtgcatggaaatca (SEQ ID NO: 12013) ggccaggatgctgaatctgctgctgctggcgctgcccgtcctggcgagccgcgcctacgcggcccctgccccaggccagg ccctgcagcgagtgggcatcgttgggggtcaggaggcccccaggagcaagtggccctggcaggtgagcctgagagtccac ggcccatactggatgcacttctgcgggggctccctcatccacccccagtgggtgctgaccgcagcgcactgcgtgggacc ggacgtcaaggatctggccgccctcagggtgcaactgcgggagcagcacctctactaccaggaccagctgctgccggtca gcaggatcatcgtgcacccacagttctacaccgcccagatcggagcggacatcgccctgctggagctggaggagccggtg aaggtctccagccacgtccacacggtcaccctgccccctgcctcagagaccttccccccggggatgccgtgctgggtcac tggctggggcgatgtggacaatgatgagcgcctcccaccgccatttcctctgaagcaggtgaaggtccccataatggaaa accacatttgtgacgcaaaataccaccttggcgcctacacgggagacgacgtccgcatcgtccgtgacgacatgctgtgt gccgggaacacccggagggactcatgccagggcgactccggagggcccctggtgtgcaaggtgaatggcacctggctgca ggcgggcgtggtcagctggggcgagggctgtgcccagcccaaccggcctggcatctacacccgtgtcacctactacttgg actggatccaccactatgtccccaaaaagccgtgagtcaggcctgggttggccacctgggtcactggaggaccaacccct gctgtccaaaacaccactgcttcctacccaggtggcgactgccccccacaccttccctgccccgtcctgagtgccccttc ctgtcctaagccccctgctctcttctgagccccttcccctgtcctgaggacccttccccatcctgagcccccttccctgt cctaagcctgacgcctgcaccgggccctccggccctcccctgcccaggcagctggtggtgggcgctaatcctcctgagtg ctggacctcattaaagtgcatggaa (SEQ ID N0:12014) tgaatctgctgctgctggcgctgcccgtcctggcgagccgcgcctacgcggcccctgccccaggccaggccctgcagcga gtgggcatcgtcgggggtcaggaggcccccaggagcaagtggccctggcaggtgagcctgagagtccacggcccatactg gatgcacttctgcgggggctccctcatccacccccagtgggtgctgaccgcagcgcactgcgtgggaccggacgtcaagg atctggccgccctcagggtgcaactgcgggagcagcacctctactaccaggaccagctgctgccggtcagcaggatcatc gtgcacccacagttctacaccgcccagatcggagcggacatcgccctgctggagctggaggagccggtgaacgtctccag ccacgtccacacggtcaccctgccccctgcctcagagaccttccccccggggatgccgtgctgggtcactggctggggcg atgtggacaatgatgagcgcctcccaccgccatttcctctgaagcaggtgaaggtccccataatggaaaaccacatttgt gacgcaaaataccaccttggcgcctacacgggagacgacgtccgcatcgtccgtgacgacatgctgtgtgccgggaacac ccggagggactcatgccagggcgactccggagggcccctggtgtgcaaggtgaatggcacctggctgcaggcgggcgtgg tcagctggggcgagggctgtgcccagcccaaccggcctggcatctacacccgtgtcacctactacttggactggatccac cactatgtccccaaaaagccgtgagtcaggcctgggttggccacctgggtcactggaggaccaacccctgctgtccaaaa caccactgcttcctacccaggtggcgactgccccccacaccttccctgccccgtcctgagtgccccttcctgtcctaagc cccctgctctcttctgagccccttcccctgtcctgaggacccttccctatcctgagcccccttccctgtcctaagcctga cgcctgcaccgggccctccagccctcccctgcccagatagctggtggtgggcgctaatcctcctgagtgctggacctcat taaagtgcatggaaatc (SEQ ID NO: 12015) accagctgacaggtggagctgccagtctccagtgctcagccctcagcggggcctgcctggcagccccacacacagagggc atcggggtggcgggggcacgtgttacacgggggccctgggtctgagtcatccacttcctccgagtctggatgggaggacc cagcgcccctcctccgccccctcctgatctggaaggataaatggggaggggagagccactgggtagaaggaacagggagt ggccagggtaagtccccactctcagagaccctgacatcagcgtcacctggagcagagtggcccagcctcagactcagagc accaagacccaggcccgcaggcctggacccaccccggtccccccgtcccagctccattcttcaccccacaatctgtagcc cccagccctgccctgtgaggcccggccaggcccacgatgctcctccttgctccccagatgctgaatctgctgctgctggc

'^* gctgcccgtcctggcgagccgcgcctacgcggcccctggtgagtcccagccggggtccaccctgcccctcaccacattcc acaggtcagggcctgggtgggttctggggaggtcgggctggccccccacacagggaagggctgggcccaggcctggggct gcttcctggtcctgacctggcacctgccccagccccaggccaggccctgcagcgagtgggcatcgtcgggggtcaggagg cccccaggagcaagtggccctggcaggtgagcctgagagtccacggcccatactggatgcacttctgcgggggctccctc atccacccccagtgggtgctgaccgcagcgcactgcgtgggaccgtgagtctcccggggcctggaggggtggggaagggc tggatgtgagccctggctcccgggtgctcctgggggctgcccagggccctgagtgggatcctccgctgcccagggacgtc aaggatctggccgccctcagggtgcaactgcgggagcagcacctctactaccaggaccagctgctgccggtcagcaggat catcgtgcacccacagttctacaccgcccagatcggagcggacatcgccctgctggagctggaggagccggtgaacgtct ccagccacgtccacacggtcaccctgccccctgcctcagagaccttccccccggggatgccgtgctgggtcactggctgg ggcgatgtggacaatgatggtgggtctggggacagtggaggtggggccagggtcttagccacagcccagcccctgggtcc ctctgggctccaggtgggggttgcccggccccctcctgaggctgcaccctcttccccacctgcagagcgcctcccaccgc catttcctctgaagcaggtgaaggtccccataatggaaaaccacatttgtgacgcaaaataccaccttggcgcctacacg ^' ggagacgacgtccgcatcgtccgtgacgacatgctgtgtgccgggaacacccggagggactcatgccaggtgggccccgc ctgtcccccgccccccgccccccaacccccactcccaggcctgttcggcgagcgctgacctctgaccttcccagggcgac tccggagggcccctggtgtgcaaggtgaatggcacctggctgcaggcgggcgtggtcagctggggcgagggctgtgccca gcccaaccggcctggcatctacacccgtgtcacctactacttggactggatccaccactatgtccccaaaaagccgtgag tcaggcctgggttggccacctgggtcactggaggaccaacccctgctgtccaaaacaccactgcttcctacccaggtggc gactgccccccacaccttccctgccccgtcctgagtgccccttcctgtcctaagccccctgctctcttctgagccccttc ccctgtcctgaggacccttccctatcctgagcccccttccctgtcctaagcctgacgcctgcaccgggccctccagccct cccctgcccagatagctggtggtgggcgctaatcctcctgagtgctggacctcattaaagtgcatggaaatcactggtgt gcatcgctgtgtttctggttgtggatgtcactgggagagaaggggtccaggtgtgctgaggacacctgccacagtgtgag gtcctagccctcaaggcacagccagtcaccgtgggac (SEQ ID NO: 12016) ggaattccgtggccaggatgctgagcctgctgctgctggcgctgcccgtcctggcgagccgcgcctacgcggcccctgcc ccagtccaggccctgcagcaagcgggtatcgtcgggggtcaggaggcccccaggagcaagtggccctggcaggtgagcct gagagtccgcgaccgatactggatgcacttctgcgggggctccctcatccacccccagtgggtgctgaccgcggcgcact gcctgggaccggacgtcaaggatctggccaccctcagggtgcaactgcgggagcagcacctctactaccaggaccagctg ctgccagtcagcaggatcatcgtgcacccacagttctacatcatccagactggagcggatatcgccctgctggagctgga ggagcccgtgaacatctccagccgcgtccacacggtcatgctgccccctgcctcggagaccttccccccggggatgccgt gctgggtcactggctggggcgatgtggacaatgatgagcccctcccaccgccatttcccctgaagcaggtgaaggtcccc ataatggaaaaccacatttgtgacgcaaaataccaccttggcgcctacacgggagacgacgtccgcatcatccgtgacga catgctgtgtgccgggaacagccagagggactcctgcaagggcgactctggagggcccctggtgtgcaaggtgaatggca cctggctacaggcgggcgtggtcagctgggacgagggctgtgcccagcccaaccggcctggcatctacacccgtgtcacc tactacttggactggatccaccactatgtccccaaaaagccgtgagtcaggcctgggtgtgccacctgggtcactggagg accaacccctgctgtccaaaacaccactgcttcctacccaggtggcgactgccccccacaccttccctgccccgtcctga gtgccccttcctgtcctaagccccctgctctcttctgagccccttcccctgtcctgaggacccttccccatcctgagccc ccttccctgtcctaagcctgacgcctgcactgctccggccctcccctgcccaggcagctggtggtgggcgctaatcctcc tgagtgctggacctcattaaagtgcatggaaatc (SEQ ID NO: 12017) gctgcccgtcctggcgagccgcgcctacgcggcccctgccccaggccaggccctgcagcgagtgggcatcgttgggggtc aggaggcccccaggagcaagtggccctggcaggtgagcctgagagtccgcgaccgatactggatgcacttctgcgggggc tccctcatccacccccagtgggtgctgaccgcagcgcactgcgtgggaccggacgtcaaggatctggccgccctcagggt gcaactgcgggagcagcacctctactaccaggaccagctgctgccggtcagcaggatcatcgtgcacccacagttctaca ccgcccagatcggagcggacatcgccctgctggagctggaggagccggtgaaggtctccagccacgtccacacggtcacc ctgccccctgcctcagagaccttccccccggggatgccgtgctgggtcactggctggggcgatgtggacaatgatgagcg cctcccaccgccatttcctctgaagcaggtgaaggtccccataatggaaaaccacatttgtgacgcaaaataccaccttg gcgcctacacgggagacgacgtccgcatcgtccgtgacgacatgctgtgtgccgggaacacccggagggactcatgccag ggcgactccggagggcccctggtgtgcaaggtgaatggcacctggctgcaggcgggcgtggtcagctggggcgagggctg tgcccagcccaaccggcctggcatctacacccgtgtcacctactacttggactggatccaccactatgtccccaaaaagc cgtgagtcaggcctggggtgtccacctgggtcactggaggaccagcccctcctgtccaaaacaccactgcttcctaccca ggcggcgactgccccccacaccttccctgccccgtcctgagtgccccttcctgtcctaagccccctgctctcttctgagc cccttcccctgtcctgaggacccttccccatcctgagcccccttccctgtcctaagcctgacgcctgcaccgggccctcc ggccctcccctgcccaggcagctggtggtgggcgctaatcc (SEQ ID NO: 12018) atctggaagcataaatggggaggggagagcccactgggtagaaggaacagggagcggccagggtaagtccccactctcag agaccctgacatcagcgtcacctggagcagagtggcccagcttcagactcagagcaccaagacccaggcctgcaggcctg gacccaccccggtccccccgtcccagctccattcttcaccccacaatctgtagcccccagccctgccctgtgaggcccgg ccaggcccacgatgctcctccttgctccccagatgctgaatctgctgctgctggcgctgcccgtcctggcgagccgcgcc tacgcggcccctggtgagtcccagccggggtccaccctgcccctcaccacattccacaggtcagggcctgggtgggttct ggggaggtcgggctggcccccacacagggaagggctgggcccaggcctggggctgcttcctggtcctgacctggcacctg ccccagccccaggccaggccctgcagcgagtgggcatcgttgggggtcaggaggcccccaggagcaagtggccctggcag gtgagcctgagagtccgcgaccgatactggatgcacttctgcgggggctccctcatccacccccagtgggtgctgaccgc agcgcactgcgtgggaccgtgagtctcccggggcctggaggggtggggaagggctggatgtgagccctggctcccgggtg ctcctgggggctgcccagggccctgagtgggatcctccgctgcccagggacgtcaaggatctggccgccctcagggtgca actgcgggagcagcacctctactaccaggaccagctgctgccggtcagcaggatcatcgtgcacccacagttctacaccg cccagatcggagcggacatcgccctgctggagctggaggagccggtgaacgtctccagccacgtccacacggtcaccctg ccccctgcctcagagaccttccccccggggatgccgtgctgggtcactggctggggcgatgtggacaatgatggtgggtc tggggacagtggaggtggggccagggtcttagccacagcccagcccctgggctccctctgggctccaggtgggggttgcc cggccccctcctgaggctgcaccctcttccccacctgcagagcgcctcccaccgccatttcctctgaagcaggtgaaggt ccccataatggaaaaccacatttgtgacgcaaaataccaccttggcgcctacacgggagacgacgtccgcatcgtccgtg acgacatgctgtgtgccgggaacacccggagggactcatgccaggtgggccccgcctgtcccccgccccccgccccccaa cccccactcccaggcctgttcggcgagcgctgacctctgaccttcccagggcgactccggagggcccctggtgtgcaagg tgaatggcacctggctgcaggcgggcgtggtcagctggggcgagggctgtgcccagcccaaccggcctggcatctacacc cgtgtcacctactacttggactggatccaccactatgtccccaaaaagccgtgagtcaggcctggggtgtccacctgggt cactggagagccagcccctcctgtccaaaacaccactgcttcctacccaggtggcgactgccccccacaccttccctgcc ccgtcctgagtgccccttcctgtcctaagccccctgctctcttctgagccccttcccctgtcctgaggacccttccccat cctgagcccccttccctgtcctaagcctgacgcctgcaccgggccctccggccctcccctgcccaggcagctggtggtgg gcgctaatcctcctgagtgctggacctcattaaagtgcatggaaatcactggtgtgcatcgctgtgtttctggttgtgga tgtcactgggagagaaggggtccaggtgtgctgaggacacctgccacagtgtgaggtcctagccctcaaggcacagccag tcaccgtgggacggggcctcctgggcagccctggtccccgaggctggcttctccccacacgatgcatccagcattcgggt cacacagagccactcgggcaactcagttgattataaaggacagccaggtccctgcaaccgggtcaagacagaaatggtca ccgggaaccccagggctgcccatcacgagcccctaccccacgcttcccacgagctcttctcccggccctcccgtccatgc ttgtgctttgcctaattgtttgcttttgagaacgggattg (SEQ ID NO: 12019) gggtctcaaggaatctttattctgcgtcttcattctgaactggatggaaccttcctgagcgcagagtcctttccactgtg aattatgggtttgttatcgtttttgttcgttgctggttgtacgtgacgggagttcagctttttgctgcgggacggcagag ataggatgcggggcttcctgagaggcgccggggcagggccgcacaggtccatccacctcccctgggaccccagccctgca gcagccccaggggagcggccggggatcggggcggggtgcccaggacgcgccctgattggcccagtgttagccaatcaagg ctctcgcatccccatggtgctgattggtccgcctcccaggcctgacccaatcggagcattcctaggaggagcggccccag agcgcctgactcgggggtcccagagccctctgcacaccacagccccggtgtccccgtgtgtccctgggttctcccagccc tggtgtcccctgagtctcttcttcaccgtcagccctggtgtctcccgtgtccctgccacaccctcatccctggtgtcccc cgtcaccccatcccctcacctcctgggctcctgaaggtcccatcttgtgggcctcattcatggaaccaggacggggcagg tggaggcctctggggagtttgtccagagaatggaggagaagcagggtcatgagcaggagcggtctgggccacccctgcct gtcccccggggggtgcagcccggaaggagtccagatggatatggccccgcagtgcagagtcagccccaaaccaggctggt cccaggcagggtgggggcaggaggagccccggagtggccctgtgttgggggtcggggggcaggcagggggtcctggggct cagaagcggaggaggtgggctggaggccccagtgaccaacaggcccacgggagtcgggaggtggggtggacggacctgca gggacagtgtcagcgctgaatgggatggagagcacagggagctggggccggggatgagaccatggggagctggggctggg gctgggactagtccatggggagctggggctgaagttgggggtgagtccatggggagctgggctgggcctcctggggttgc acctgcactcctctctgctcttccctctgcgtatgaagctcagatcccatgataaggaggcacctgcagaccaggggacc tgcacggacagccccagaggtggacattgaggactcgtaggaggacttgggtctcatacggcgggtggggagcagggccc cttcctggctgaggacacttggtgctgtcccctctcaaggctgtttccccatctgacaaaggggtctcatgtgagccccc aaccaagtgagtcgaggagggctggccccacccccgtggatttggagtccgtaggaggggtgtcacccgtcacgtcccca ccccgtgggcaccttcccgtctcttggagcgtggcccatggacatgagttcctcacccgtgtccctcttggggaaacagg tttcaggagcgacgggtcttgtagcctggggcagccaggccacctgggtgcagctatgcctgaaggcctcctggcaccga gacaggggcaggagcagatcccaccagcgggaaggtggtgcgttctgatgctgggatccaccagctgacaggtggagctg cgagcctccagtgctcagccctcggcggggcctgcctggcagccccacacacagagggcatcggggtggcgggggcacgt gttacacgggggccctgggtctgagtcatccacttcctccgagtctggatgggaggacccagcgcccctcctccgccccc tcctgatctggaaggataaatggggaggggagagcccgctgggtagaaggaacagggagtggccagggtaagtccctact ctcagagaccctgacatcagtgtcacctggagcagagtggcccagcctcagactcagagcaccaagacccaggcccgcag gcctggacccaccccggtccccccgtcccagctccattcttcaccccacaatctgtagcccccagccctgccctgtgagg cccggccaggcccacgatgctcctccttgctccccagatgctgagcctgctgctgctggcgctgcccgtcctggcgagcc cggcctacgcggcccctggtgagtcccagccggggtccaccctgcccctcaccacattccacaggtcagggcctgggtgg gttctggggaggctgggctggcccccacacagggaagggctgggcccaggcgtggggctgcttcctggtcctgacctggc acctgccccagccccagtccaggccctgcagcaagcgggtatcgtcgggggtcaggaggcccccaggagcaagtggccct ggcaggtgagcctgagagtccgcgaccgatactggatgcacttctgtgggggctccctcatccacccccagtgggtgctg accgcggcgcactgcctgggaccgtgagtctcccagggcctggaggggtgggcaagggctggatgtgagccctggctccc gggtgctcctgggggctgcccagggccctgagtgggatcctccgctgcccagggacgtcaaggatctggccaccctcagg gtgcaactgcgggagcagcacctctactaccaggaccagctgctgccggtcagcaggatcatcgtgcacccacagttcta catcatccagactggagcggatatcgccctgctggagctggaggagcccgtgaacatctccagccgcgtccacacggtca tgctgccccctgcctcggagaccttccccccggggatgccgtgctgggtcactggctggggcgatgtggacaatgatggt gggtctggggacagtgggaggtggggccagggtcttagccacagcccagcccctgggctccaggtgggggttgcccggcc ccctcctcaggctgcaccctcttccccacctgcagagcccctcccaccgccatttcccctgaagcaggtgaaggtcccca taatggaaaaccacatttgtgacgcaaaataccaccttggcgcctacacgggagacgacgtccgcatcatccgtgacgac atgctgtgtgccgggaacacccggagggactcatgccaggtgggccccgcgtgtcccccgccccccgcaccccaaccccc actcccaggcctgttcggcgagcgctgacctctgaccttcccagggcgactctggagggcccctggtgtgcaaggtgaat ggcacctggctacaggcgggcgtggtcagctgggacgagggctgtgcccagcccaaccggcctggcatctacacccgtgt cacctactacttggactggatccaccactatgtccccaaaaagccgtgagtcaggcctggggtgtccacctgggtcactg gagagccagcccctcctgtccaaaacaccactgcttcctacccaggtggcgactgccccccacaccttccctgccccgtc ctgagtgccccttcctgtcctaagccccctgctctcttctgagccccttcccctgtcctgaggacccttccccatcctga gcccccttccctgtcctaagcctgacgcctgcactgggccctccggccctcccctgcccaggcagctggtggtgggcgct aatcctcctgagtgctggacctcattaaagtgcatggaaatcactggtgtgcatcgctgtgtttctggttgtggatgtca ctgggagagaaggggtccaggtgtgctgaggacacctgccacagtgcgaggtcctagccctcaaggcacagccagtcacc gtgggacggggcctcctgggcagccctggtccccggggctggcttctccccacacgatgcatccagcattcgggtcacac agagccactcgggcaactcagttgattataaaggacagccaagtccctgcaaccgggtcaagacagagaatggtcgccgg gagccccagggctgcccatcacgagcccctaccccacgcttcccacgagctcttctcccggcccctctgtccactgcttg tgctttgccctagttgtttgctttgagacaggatctcgctgtgtcatccaggctgaagtgcagtggtgtgatcagggctc actgtagccttgaactcctgggctcaagcgatcctcccatcttggcctcccatatagctgggccacaggagtgagccacc acgcccagttaatttttgtattttcagtagagatggggtttcgccatgttggccagtctggtctcgaactcctgacctca agtgatctgcccgcctcggcctcccaaagtgctgggatgacaggcgtgagccaccgcacccagcctgagtttgacatttt caaattcattttgaggtctttctctacatcaatacatgagccctccgcgtccggcgagtgttgcattttatcccgggctc ttgtttgcattttatatttgaacatgattacattcaggaatgaaatgcggggctgttctggttgaaaacaactctctaaa gaaacattcactctttccttccaactgtcagatgcagagatgtgcatttagtctctccaatctctgcaaatgacctctgt cctcacaaggggtggactcgacttccagcgccctctccagccccacgtgacctctgcctctgcagcccctgaaggcccat ccctcggctcctgttctgcaggcccagcgtcttgtctatgaagatggacctggaactcgggccctccttcctccctctgg cccatcccaccttctagggatcacagagacagcacggggtgacccccagggaacactgagcccctagaagcacttccaca cgcccactggaggttttgcggggtgggagtcggagggatgagaccccgaagggaagcaagacggcccctcaggacagggc tgccggtgtaaggaaaggtggacagcaggggccggtcactgggtggagggggagggcaggctccagccccagagcttccc aaattagatctaagatccctgggaagctcagtgaagctcagcgcagtgacactggcagatgtgagcgtcagcttcagcag gaagggtctctcaggacgtgacaggcaggctgctggccagggctgcagccacctgcgttttgactgggacgggggcacct gatccaaggtcacccacgtggctgccggcaggaggccctggttccccgtcacaagggggtgtgagggggaaggccaagtg gtggccacanggttnccaccgagagggacagtgcccaagttggccaagccaccctnggacaagaaacaatnccaagtctt nccaaggtccttggacaacaaggagaancccccccagcttgggggcnattaaccaagggccangnccccccttcccggtt ctggacccaccccggtccccccgtcccagcttccattcttcaccccacaatctgtagcccccagccctgccctgtgaggc ccggccaggcccacgatgctcctccttgctccccagatgctgaatctgctgctgctggcgctgcccgtcctggcgagccg cgcctacgcggcccctggtgagtcccagccggggtccaccctgcccctcaccacattccacaggtcagggcctgggtggg ttctggggaggccgggctggcccccacacagggaagggctgggcccaggcctggggctgcttcctggtcctgacctggca cctgccccagccccaggccaggccctgcagcgagtgggcatcgttgggggtcaggaggcccccaggagccagatcggagc ggacatcgccctgctggagctggaggagccggtgaaggtctccagccacgtccacacggtcaccctgccccctgcctcag agaccttccccccggggatgccgtgctgggtcactggctggggcgatgtggacaatgatggtgggtctggggacagtgga ggtggggccagggtcttagccacagcccagcccctgggctccctctgggctccaggtgggggttgcccggccccctcctg aggctgcaccctcttccccacctgcagagcgcctcccaccgccatttcctctgaagcaggtgaaggtccccataatggaa aaccacatttgtgacgcaaaataccaccttggcgcctacacgggagacgacgtccgcatcgtccgtgacgacatgctgtg tgccgggaacacccggagggactcatgccaggtgggccccgcgtgtcccccgccccccgcaccccaacccccactcccag gcctgttcggcgagcgctgacctctgaccttcccagggcgactccggagggcccctggtgtgcaaggtgaatggcacctg gctgcaggcgggcgtggtcagctggggcgagggctgtgcccagcccaaccggcctggcatctacacccgtgtcacctact acttggactggatccaccactatgtccccaaaaagccgtgagtcaggcctgggttggccacctgggtcactggaggacca acccctgctgtccaaaacaccactgcttcctacccaggtggcgactgccccccacaccttccctgccccgtcctgagtgc cccttcctgtcctaagccccctgctctcttctgagccccttcccctgtcctgaggacccttccccatcctgagccccctt ccctgtcctaagcctgacgcctgcactgggccctccggccctcccctgcccaggcagctggtggtgggcgctaatcctcc tgagtgctggacctcattaaagtgcatggaaatcactggtgtgcatcgctgtgtttctggttgtggatgtcactgggaga gaaggggtccaggtgtgctgaggacacctgccacagtgtgaggtcctagccctcaaggcacaagccagtcaccgtgggac ggggcctctgggcagccctggtccccgagctggcttccaggatgctgaatctgctgctgctggcgctgcccgtcctggcg agccgcgcctacgcggcccctgccccaggccaggccctgcagcgagtgggcatcgttgggggtcaggaggcccccaggag caagtggccctggcaggtgagcctgagagtccacggcccatactggatgcacttctgcgggggctccctcatccaccccc agtgggtgctgaccgcagcgcactgcgtgggaccggacgtcaaggatctggccgccctcagggtgcaactgcgggagcag cacctctactaccaggaccagctgctgccggtcagcaggatcatcgtgcacccacagttctacaccgcccagatcggagc ggacatcgccctgctggagctggaggagccggtgaaggtctccagccacgtccacacggtcaccctgccccctgcctcag agaccttccccccggggatgccgtgctgggtcactggctggggcgatgtggacaatgatgagcgcctcccaccgccattt cctctgaagcaggtgaaggtccccataatggaaaaccacatttgtgacgcaaaataccaccttggcgcctacacgggaga cgacgtccgcatcgtccgtgacgacatgctgtgtgccgggaacacccggagggactcatgccagggcgactccggagggc ccctggtgtgcaaggtgaatggcacctggctgcaggcgggcgtggtcagctggggcgagggctgtgcccagcccaaccgg cctggcatctacacccgtgtcacctactacttggactggatccaccactatgtccccaaaaagccgtgagtcaggcctgg gtgtgccacctgggtcactggaggaccaacccctgctgtccaaaacaccactgcttcctacccaggtggcgactgccccc cacaccttccctgccccgtcctgagtgccccttcctgtcctaagccccctgctctcttctgagccccttcccctgtcctg aggacccttccccatcctgagcccccttccctgtcctaagcctgacgcctgcactgctccggccctcccctgcccaggca gctggtggtgggcgctaatcctcctgagtgctggacctcattaaagtgcatggaaatcaggccaggatgctgaatctgct gctgctggcgctgcccgtcctggcgagccgcgcctacgcggcccctgccccaggccaggccctgcagcgagtgggcatcg ttgggggtcaggaggcccccaggagcaagtggccctggcaggtgagcctgagagtccacggcccatactggatgcacttc tgcgggggctccctcatccacccccagtgggtgctgaccgcagcgcactgcgtgggaccggacgtcaaggatctggccgc cctcagggtgcaactgcgggagcagcacctctactaccaggaccagctgctgccggtcagcaggatcatcgtgcacccac agttctacaccgcccagatcggagcggacatcgccctgctggagctggaggagccggtgaaggtctccagccacgtccac acggtcaccctgccccctgcctcagagaccttccccccggggatgccgtgctgggtcactggctggggcgatgtggacaa tgatgagcgcctcccaccgccatttcctctgaagcaggtgaaggtccccataatggaaaaccacatttgtgacgcaaaat accaccttggcgcctacacgggagacgacgtccgcatcgtccgtgacgacatgctgtgtgccgggaacacccggagggac tcatgccagggcgactccggagggcccctggtgtgcaaggtgaatggcacctggctgcaggcgggcgtggtcagctgggg cgagggctgtgcccagcccaaccggcctggcatctacacccgtgtcacctactacttggactggatccaccactatgtcc ccaaaaagccgtgagtcaggcctgggttggccacctgggtcactggaggaccaacccctgctgtccaaaacaccactgct tcctacccaggtggcgactgccccccacaccttccctgccccgtcctgagtgccccttcctgtcctaagccccctgctct cttctgagccccttcccctgtcctgaggacccttccccatcctgagcccccttccctgtcctaagcctgacgcctgcacc gggccctccggccctcccctgcccaggcagctggtggtgggcgctaatcctcctgagtgctggacctcattaaagtgcat ggaatgaatctgctgctgctggcgctgcccgtcctggcgagccgcgcctacgcggcccctgccccaggccaggccctgca gcgagtgggcatcgtcgggggtcaggaggcccccaggagcaagtggccctggcaggtgagcctgagagtccacggcccat actggatgcacttctgcgggggctccctcatccacccccagtgggtgctgaccgcagcgcactgcgtgggaccggacgtc aaggatctggccgccctcagggtgcaactgcgggagcagcacctctactaccaggaccagctgctgccggtcagcaggat catcgtgcacccacagttctacaccgcccagatcggagcggacatcgccctgctggagctggaggagccggtgaacgtct ccagccacgtccacacggtcaccctgccccctgcctcagagaccttccccccggggatgccgtgctgggtcactggctgg ggcgatgtggacaatgatgagcgcctcccaccgccatttcctctgaagcaggtgaaggtccccataatggaaaaccacat ttgtgacgcaaaataccaccttggcgcctacacgggagacgacgtccgcatcgtccgtgacgacatgctgtgtgccggga acacccggagggactcatgccagggcgactccggagggcccctggtgtgcaaggtgaatggcacctggctgcaggcgggc gtggtcagctggggcgagggctgtgcccagcccaaccggcctggcatctacacccgtgtcacctactacttggactggat ccaccactatgtccccaaaaagccgtgagtcaggcctgggttggccacctgggtcactggaggaccaacccctgctgtcc aaaacaccactgcttcctacccaggtggcgactgccccccacaccttccctgccccgtcctgagtgccccttcctgtcct aagccccctgctctcttctgagccccttcccctgtcctgaggacccttccctatcctgagcccccttccctgtcctaagc ctgacgcctgcaccgggccctccagccctcccctgcccagatagctggtggtgggcgctaatcctcctgagtgctggacc tcattaaagtgcatggaaatcaccagctgacaggtggagctgccagtctccagtgctcagccctcagcggggcctgcctg gcagccccacacacagagggcatcggggtggcgggggcacgtgttacacgggggccctgggtctgagtcatccacttcct ccgagtctggatgggaggacccagcgcccctcctccgccccctcctgatctggaaggataaatggggaggggagagccac tgggtagaaggaacagggagtggccagggtaagtccccactctcagagaccctgacatcagcgtcacctggagcagagtg gcccagcctcagactcagagcaccaagacccaggcccgcaggcctggacccaccccggtccccccgtcccagctccattc ttcaccccacaatctgtagcccccagccctgccctgtgaggcccggccaggcccacgatgctcctccttgctccccagat gctgaatctgctgctgctggcgctgcccgtcctggcgagccgcgcctacgcggcccctggtgagtcccagccggggtcca ccctgcccctcaccacattccacaggtcagggcctgggtgggttctggggaggtcgggctggccccccacacagggaagg gctgggcccaggcctggggctgcttcctggtcctgacctggcacctgccccagccccaggccaggccctgcagcgagtgg gcatcgtcgggggtcaggaggcccccaggagcaagtggccctggcaggtgagcctgagagtccacggcccatactggatg cacttctgcgggggctccctcatccacccccagtgggtgctgaccgcagcgcactgcgtgggaccgtgagtctcccgggg cctggaggggtggggaagggctggatgtgagccctggctcccgggtgctcctgggggctgcccagggccctgagtgggat cctccgctgcccagggacgtcaaggatctggccgccctcagggtgcaactgcgggagcagcacctctactaccaggacca gctgctgccggtcagcaggatcatcgtgcacccacagttctacaccgcccagatcggagcggacatcgccctgctggagc tggaggagccggtgaacgtctccagccacgtccacacggtcaccctgccccctgcctcagagaccttccccccggggatg ccgtgctgggtcactggctggggcgatgtggacaatgatggtgggtctggggacagtggaggtggggccagggtcttagc cacagcccagcccctgggtccctctgggctccaggtgggggttgcccggccccctcctgaggctgcaccctcttccccac ctgcagagcgcctcccaccgccatttcctctgaagcaggtgaaggtccccataatggaaaaccacatttgtgacgcaaaa taccaccttggcgcctacacgggagacgacgtccgcatcgtccgtgacgacatgctgtgtgccgggaacacccggaggga ctcatgccaggtgggccccgcctgtcccccgccccccgccccccaacccccactcccaggcctgttcggcgagcgctgac ctctgaccttcccagggcgactccggagggcccctggtgtgcaaggtgaatggcacctggctgcaggcgggcgtggtcag ctggggcgagggctgtgcccagcccaaccggcctggcatctacacccgtgtcacctactacttggactggatccaccact atgtccccaaaaagccgtgagtcaggcctgggttggccacctgggtcactggaggaccaacccctgctgtccaaaacacc actgcttcctacccaggtggcgactgccccccacaccttccctgccccgtcctgagtgccccttcctgtcctaagccccc tgctctcttctgagccccttcccctgtcctgaggacccttccctatcctgagcccccttccctgtcctaagcctgacgcc tgcaccgggccctccagccctcccctgcccagatagctggtggtgggcgctaatcctcctgagtgctggacctcattaaa gtgcatggaaatcactggtgtgcatcgctgtgtttctggttgtggatgtcactgggagagaaggggtccaggtgtgctga ggacacctgccacagtgtgaggtcctagccctcaaggcacagccagtcaccgtgggacggaattccgtggccaggatgct gagcctgctgctgctggcgctgcccgtcctggcgagccgcgcctacgcggcccctgccccagtccaggccctgcagcaag cgggtatcgtcgggggtcaggaggcccccaggagcaagtggccctggcaggtgagcctgagagtccgcgaccgatactgg atgcacttctgcgggggctccctcatccacccccagtgggtgctgaccgcggcgcactgcctgggaccggacgtcaagga tctggccaccctcagggtgcaactgcgggagcagcacctctactaccaggaccagctgctgccagtcagcaggatcatcg tgcacccacagttctacatcatccagactggagcggatatcgccctgctggagctggaggagcccgtgaacatctccagc cgcgtccacacggtcatgctgccccctgcctcggagaccttccccccggggatgccgtgctgggtcactggctggggcga tgtggacaatgatgagcccctcccaccgccatttcccctgaagcaggtgaaggtccccataatggaaaaccacatttgtg acgcaaaataccaccttggcgcctacacgggagacgacgtccgcatcatccgtgacgacatgctgtgtgccgggaacagc cagagggactcctgcaagggcgactctggagggcccctggtgtgcaaggtgaatggcacctggctacaggcgggcgtggt cagctgggacgagggctgtgcccagcccaaccggcctggcatctacacccgtgtcacctactacttggactggatccacc actatgtccccaaaaagccgtgagtcaggcctgggtgtgccacctgggtcactggaggaccaacccctgctgtccaaaac accactgcttcctacccaggtggcgactgccccccacaccttccctgccccgtcctgagtgccccttcctgtcctaagcc ccctgctctcttctgagccccttcccctgtcctgaggacccttccccatcctgagcccccttccctgtcctaagcctgac gcctgcactgctccggccctcccctgcccaggcagctggtggtgggcgctaatcctcctgagtgctggacctcattaaag tgcatggaaatcgctgcccgtcctggcgagccgcgcctacgcggcccctgccccaggccaggccctgcagcgagtgggca tcgttgggggtcaggaggcccccaggagcaagtggccctggcaggtgagcctgagagtccgcgaccgatactggatgcac ttctgcgggggctccctcatccacccccagtgggtgctgaccgcagcgcactgcgtgggaccggacgtcaaggatctggc cgccctcagggtgcaactgcgggagcagcacctctactaccaggaccagctgctgccggtcagcaggatcatcgtgcacc cacagttctacaccgcccagatcggagcggacatcgccctgctggagctggaggagccggtgaaggtctccagccacgtc cacacggtcaccctgccccctgcctcagagaccttccccccggggatgccgtgctgggtcactggctggggcgatgtgga caatgatgagcgcctcccaccgccatttcctctgaagcaggtgaaggtccccataatggaaaaccacatttgtgacgcaa aataccaccttggcgcctacacgggagacgacgtccgcatcgtccgtgacgacatgctgtgtgccgggaacacccggagg gactcatgccagggcgactccggagggcccctggtgtgcaaggtgaatggcacctggctgcaggcgggcgtggtcagctg gggcgagggctgtgcccagcccaaccggcctggcatctacacccgtgtcacctactacttggactggatccaccactatg tccccaaaaagccgtgagtcaggcctggggtgtccacctgggtcactggaggaccagcccctcctgtccaaaacaccact gcttcctacccaggcggcgactgccccccacaccttccctgccccgtcctgagtgccccttcctgtcctaagccccctgc tctcttctgagccccttcccctgtcctgaggacccttccccatcctgagcccccttccctgtcctaagcctgacgcctgc accgggccctccggccctcccctgcccaggcagctggtggtgggcgctaatccatctggaagcataaatggggaggggag agcccactgggtagaaggaacagggagcggccagggtaagtccccactctcagagaccctgacatcagcgtcacctggag cagagtggcccagcttcagactcagagcaccaagacccaggcctgcaggcctggacccaccccggtccccccgtcccagc tccattcttcaccccacaatctgtagcccccagccctgccctgtgaggcccggccaggcccacgatgctcctccttgctc cccagatgctgaatctgctgctgctggcgctgcccgtcctggcgagccgcgcctacgcggcccctggtgagtcccagccg gggtccaccctgcccctcaccacattccacaggtcagggcctgggtgggttctggggaggtcgggctggcccccacacag ggaagggctgggcccaggcctggggctgcttcctggtcctgacctggcacctgccccagccccaggccaggccctgcagc gagtgggcatcgttgggggtcaggaggcccccaggagcaagtggccctggcaggtgagcctgagagtccgcgaccgatac tggatgcacttctgcgggggctccctcatccacccccagtgggtgctgaccgcagcgcactgcgtgggaccgtgagtctc ccggggcctggaggggtggggaagggctggatgtgagccctggctcccgggtgctcctgggggctgcccagggccctgag tgggatcctccgctgcccagggacgtcaaggatctggccgccctcagggtgcaactgcgggagcagcacctctactacca ggaccagctgctgccggtcagcaggatcatcgtgcacccacagttctacaccgcccagatcggagcggacatcgccctgc tggagctggaggagccggtgaacgtctccagccacgtccacacggtcaccctgccccctgcctcagagaccttccccccg gggatgccgtgctgggtcactggctggggcgatgtggacaatgatggtgggtctggggacagtggaggtggggccagggt cttagccacagcccagcccctgggctccctctgggctccaggtgggggttgcccggccccctcctgaggctgcaccctct tccccacctgcagagcgcctcccaccgccatttcctctgaagcaggtgaaggtccccataatggaaaaccacatttgtga cgcaaaataccaccttggcgcctacacgggagacgacgtccgcatcgtccgtgacgacatgctgtgtgccgggaacaccc ggagggactcatgccaggtgggccccgcctgtcccccgccccccgccccccaacccccactcccaggcctgttcggcgag cgctgacctctgaccttcccagggcgactccggagggcccctggtgtgcaaggtgaatggcacctggctgcaggcgggcg tggtcagctggggcgagggctgtgcccagcccaaccggcctggcatctacacccgtgtcacctactacttggactggatc caccactatgtccccaaaaagccgtgagtcaggcctggggtgtccacctgggtcactggagagccagcccctcctgtcca aaacaccactgcttcctacccaggtggcgactgccccccacaccttccctgccccgtcctgagtgccccttcctgtccta agccccctgctctcttctgagccccttcccctgtcctgaggacccttccccatcctgagcccccttccctgtcctaagcc tgacgcctgcaccgggccctccggccctcccctgcccaggcagctggtggtgggcgctaatcctcctgagtgctggacct cattaaagtgcatggaaatcactggtgtgcatcgctgtgtttctggttgtggatgtcactgggagagaaggggtccaggt gtgctgaggacacctgccacagtgtgaggtcctagccctcaaggcacagccagtcaccgtgggacggggcctcctgggca gccctggtccccgaggctggcttctccccacacgatgcatccagcattcgggtcacacagagccactcgggcaactcagt tgattataaaggacagccaggtccctgcaaccgggtcaagacagaaatggtcaccgggaaccccagggctgcccatcacg agcccctaccccacgcttcccacgagctcttctcccggccctcccgtccatgcttgtgctttgcctaattgtttgctttt gagaacgggattg (SEQ ID NO:12020) ttctccttctccccaacagttccccagggacctctctctaatcagccctctggcccaggcagtcagatcatcttctcgaa ccccgagtgacaagcctgtagcccatgttgtagcaaaccctcaagctgaggggcagctccagtggctgaaccgccgggcc aatgccctcctggccaatggcgtggagctgagagataaccagctggtggtgccatcagagggcctgtacctcat tactc ccaggtcctcttcaagggccaaggctgcccctccacccatgtgctcctcacccacaccatcagccgcatcgccgtctcct accagaccaaggtcaacctcctctctgccatcaagagcccctgccagagggagaccccagagggggctgaggccaagccc tggtatgagcccatctatctgggaggggtcttccagctggagaagggtgaccgactcagcgctgagatcaatcggcccga ctatctcgactttgccgagtctgggcaggtctactttgggatcattgccctgtgaggaggacgaacatccaaccttccca aacgcctcccctgccccaatccctttattaccccctccttcagacaccctcaacctcttctggctcaaaaagagaattgg gggcttagggtcggaacccaagcttagaactttaagcaacaagaccaccacttcgaaacctgggattcaggaatg gtgg cctgcacagtgaattgctggcaaccactaagaattcaaactggggcctccagaactcactggggcctacagctttgatcc ctgacatctggaatctggagaccagggagcctttggttctggccagaatgctgcaggacttgagaagacctcacctagaa attgacacaagtggaccttaggccttcctctctccagatgtttccagacttccttgagacacggagcccagccctcccca tggagccagctccctctatttatgtttgcacttgtgattatttattatttatttattatttatttatttacagatgaatg tatttatttgggagaccggggtatcctgggggacccaatgtaggagctgccttggctcagacatgttttccgtgaaaacg gagctgaacaataggctgttcccatgtagccccctggcctctgtgccttcttttgattatgttttttaaaatatttatct gattaagttgtctaaacaatgctgatttggtgaccaactgtcactcattgctgagcctctgctccccaggggagttgtgt ctgtaatcgccctactattcagtggcgagaaataaagtttgctt (SEQ ID NO: 12021) tacgggccgggcactcccgagctgctgctcgagggcgccgagacggtgactccagtgctggacccggccaggagacaagg gtacgggcctctctggtacacgagcgtggggttcggcggcctggtgcagctccggaggggcgagagggtgtacgtcaaca tcagtcaccccgatatggtggacttcgcgagagggaagaccttctttggggccgtgatggtggggtgagggaatatgagt gcgtggtgcgagtgcgtgaatattgggggnccggacgcccaggaccccatggcagtgggaaaaatgtaggagactgtttg gaaattgattttgaacctgatgaaaataaagaatggaaagcttcagtgctgccgataaagatgctgagttgcgacacacg tcttaattcagggtgggtgcacgggtgcgggttaaatattctcagtactcttctggttgcttgaaacaattcatcacaac acagtgtatggcctttgctcctagggatgatggtctgcctgtcccaccccctccctgcctctgaatggccaggccccacc attagcccagttggagggtgggaggaagggggacttctcaaactccgaagcttctctaggcatcctgattttcagggcca catggtcccaaccagactctgcaccatactcttttctcttgggtaccccccaacagtgagaggggtcattacagagccca gcaagcaccactcagaaaggcccagcagcagagtaagcccctatcatgacagaggaatgaagcctggaggggccccgcac ttctccccctagagctgcctgaaggcctctctgtctcctacccgacagtcaactcttctcctccaaggagcttaattcaa ggctcatggggtctgaagggaggaggctgaaggagaaagaaggggagaatattagagagagatggggatggcaggaagga gcctgtggtgcctgaaaacaccaggaagttctggggaggaggaaaaaccgatgccccacttagggtgtcccatttagggt gagacggaaaatcctcacctttttttcacactttaggtcccccttcccaaaagtgagtaagtgtgggtgcttctgggatg agtaacagtgtcccccattacttcatggctgactttcagccacaggctggaggaggcagagggtgacccaaggccctatc taggtcaccccaatgggtcaccctaccccctcagcctaccacatggttttctcctgcctggcaccccagggctggaggta aagcctaattttccgaacttcagttggggctcccagtctaggggggctcaatttccgtctccatattttgttttggaatt attatttttttgagacagggtctcgttctgtcacccagacgggggtacagtggcatgatcatagcttactgtaacctcaa actcctgggcttgagtgatcctcctgcctcagcctcctgaggagctaggattacaggcatgcaccactacacctgactaa tctttaattttttttctagaaacaaggtcttgctatgttgcacaggctggtcttgaactagtgggctcaagtggtcctcc cacctcagcctcccaaagtgttgggataacaggcatgagccactgcgccccacccttatttgtctttgactctctccaga agagccttcatccagggagggggtgcttttctctttccggattacccacctctcacctctcccctccttcaccacaaaga ccagtgggaccaagccggcatgtgagtccttcacccacatcttattcctatgtttcattcttttttaaaaaatagagaca ggatctcactatgttgcccaggttgctctggaactcctgggttcaagcgatcctctcaccttggccttgcaaagtggtag gattacaggtgcatgccaccacgtccggcagttcggttccttgttctttattgtcctcagtctcttcgatttcacccact gagagaatggaaggggatagaacagctggaaactggttgaaggaagccagaattcactaagtgcccactgtgccaagggc tgagtgaggtcctctgatggaggtcaggccttctctcacatgccctatgtgtggtggacattcctatccccattggatag ataggttaagtggctggttcaggttgcagagttaggacagggtgatttgaagcctagacacccgaatctctggaagtccc ttggctgtgtgattcaggtacctgagaatgcggctcctctccagctctctccggactgctggccagctgcaacagccgga aatctcacctgagctgcaggattttcccagcaaggattggaattcccagagttggaaattcccatgccctgagggagagg taattaggttcaggctcttgtttcctgggggatggggaatattctgttgggctttgtttatgtagggtctccagggccct aggagtctaaggatgggactgggtccgagggatcttaaagcctgtggagagaggacttagggagcttcttcccacccaca agaagaggcagatgcagaattaattccaagaaggagaccatgtttcttttctaagcaaactttatttctcgccactgaat agtagggcgattacagacacaactccctggggagcagaggcctcagcaatgagtgacagttggtcaccaaatcagcattg tttagacaacttaatcagataatattttaaaaaacataatcaaaagaaggcacagaggccagggggctacatgggaacag cctattgttcagcctccgttttcacggaaaacatgtctgagccaaggcagctcctacattgggtcccccaggataccccg gtctcccaaataaatacattcatctgtaaataaataaataataaataaataataaataatcacaagtgcaaacataaata gagggagctggctccatggggagggctgggctccgtgtctcaaggaagtctggaaacatctggagagaggaaggcctaag gtccacttgtgtcaatttctaggtgaggtcttctcaagtcctgcagcattctggccagaaccaaaggctccctggtctcc agattccagatgtcagggatcaaagctgtaggccccagtgagttctggaggccccagtttgaattcttagtggttgccag cacttcactgtgcaggccacacattcctgaatcccaggtttcgaagtggtggtcttgttgcttaaagttctaagcttggg ttccgaccctaagcccccaattctctttttgagccagaagaggttgagggtgtctgaaggagggggtaataaagggattg gggcaggggaggcgtttgggaaggttggatgttcgtcctcctcacagggcaatgatcccaaagtagacctgcccagactc ggcaaagtcgagatagtcgggccgattgatctcagcgctgagtcggtcacccttctccagctggaagacccctcccagat agatgggctcataccagggcttggcctcagccccctctggggtctccctctggcaggggctcttgatggcagagaggagg ttgaccttggtctggtaggagacggcgatgcggctgatggtgtgggtgaggagcacatgggtggaggggcagccttggcc cttgaagaggacctgggagtagatgaggtacaggccctctgatggcaccaccagctggttatctctcagctccacgccat tggccaggagggcattggcccggcggttcagccactggagctgcccctcagcttgagggtttgctggagggagggagaga gggagaggagagtcagtgtggccatgtcggttcactctccacatcctggccctcgagctctgcccaccccacatccggtt cctgtcctctctgtctgtcatcccacatcccacctggccatgacgttctgagtatcccactaaggcctgtgctgttcctc cacccttcccttgagctcagcgagtccttctcacattgtctccaagttctgcctaccatcagccgggcttcaatccccaa atcctagccctccaagttccaagacacatcctcagagctcttacctacaacatgggctacaggcttgtcactcggggttc gagaagatgatcctgaagaggagagagaaaagaaaaagctgagacccttaaacttcctagaaaatacccccctactttca cctccatccatcctcccccaagaccaaaactttaaatttcccccactgctttccataccggtactaaccctaccccccaa acccaaacccagaattaggaaagaggtttggagacacttactgactgcctgggccagagggctgattagagagaggtccc tggggaactgttggggagaaggagaatggttaacatcgagggagtcacccttaaaggaggaacagctggctgcctgtctg gcctgcgctcttagccctgaggtgtctggttttctctctccattcatctgtgtattcaccttccaggcattcaacagctc tttccctgagtgtcttctgtgtgccagacaccctatcttcttctctccttatctcccccatctctctccttagctgtcat atttcccgctctttctgtctcaccatctttattcatatcacttgtttcttcccccatctctcttctcacaccccacatct gtctccatatcttatttatatatctgcttgttcattcattcattcattcattcactccatacacacttagtgagcacctt ccatgtgccagacatcctgtctctccatctttctctctctctcttccccatctcttgccacatctctttctgcatccccg tctttctccacgtttttttctctccatccctccctatcagcgcacatctttcacccatcccatctctctccctctcttgc gtctccatttccccttgggtgggagagtggatgaaggctggccaggcactcacctcttccctctgggggccgatcactcc aaagtgcagcaggcagaagagcgtggtggcgcctgccacgatcaggaaggagaagaggctgaggaacaagcaccgcctgg agccctggggcccccctgtcttcttggggagcgcctcctcggccagctccacgtcccggatcatgctttcagtgctcatg gtgtcctttccaggggagagagggtggagccgtgggtcagtatgtgagaggaagagaacctgcctggcagcttgtcaggg gatgtggcgtctgagggttgttttcagggggggtctgtagttgcttctctccctcttagctggtcctctgctgtccttgc tgagggagcgtctgctggctgggtgtgccaacaactgcctttatatgtccctggggcgagaggagggcggggaaagaatc attcaaccagcggaaaacttccttggtggagaaacccatgagctcatctggaggaagcggtagtgggccctgcaccttct gtctcggtttcttctccatcgcgggggcggggatttggaaagttggggacacacaagcatcaaggatacccctcacactc cccatcctccctgctccgattccgaggggggtcttctgggccactgactgatttgtgtgtaggaccctggaggctgaacc ccgtccccatgcccctcaaaacctattgcctccatttcttttggggaccaggtctgtggtctgtttccttctaacttcca gacaggatgcaggaaaaagatagaactagaactgggaggggcttcagaaagctgagtccgttgagggagagaaaacgggg ttggagggaaaagctgtgttgagtcctgaggcctgtgtttgggccctgcggggagaaggagctgggggcttggtggcagg cttgaggcctcaggaaaggctgggtgcgggtagcagggacaagcctgggacagccccggggagtgaaatcacccccggga attcacagaccccactggggcaggccctcttctttcattctgacccggagactcataatgcttggttcagtcttggcttc caaggaactctggggtccctgatttttttcatgaagctctcacttctcagggccccagtgtgtggccatatcttcttaaa cgtcccctgtattccatacctggaggtcctggaggctctttcactccctggggccctctacatggccctgtcttcgttaa gtgggggtccccatactcgacttccatagccctggacattctcctacccattgctgtggtcacatctccccagaggtctc ctgtaacccattcctcagagccgctacatgtggccatatctcccaggagctccctgacccccgcccctccagaccctgac ttttccttcgtcttctcagcttctcctttgcttcccctgcagcagtctggcggcctcacctggtgagtccatcacatatc cctgaagctctctgagcccttatccttttgttctccccacagctcttgctccctttgagccctctgtccctccctccatt ccttagatagactgggaagttctcactcccagacacacacacacaagcagacagcatttcagagaaaagaggtttattgg gcttcatcgagggtgcagatgcctccgtgtggggctctggtcggcagctggctttcagagcctttccctgccttctgggg ccctgtgatccctcatgcctacttctttctctcttggtcagccttgtgcgcatgccctctcactcttcatctcttgggcc tgtctctgtttctccttggatgttcttctattattcccctctctccatcctccataaataaataatttaatttttttgcc ttcataaatagtcccctccctgcctctagtcatcccccaagctcctccatgtgcctgctcttcctctgtgtgtggatcta ggccccacctagctggtgggacagaccaacagctttgggctgggaattcctaggcaggcttgaaatcctcagccagacag acatcagggatggttcagggaggtgtggtcccctgggatgcctagaattccttctttgaaagctccggtgacttgatcag ggaagacttgagctgttggaatggccaaaggagaggtggtgacgacccctgaaatggtcagaatggaggcagaatgggga gaaggtcttgaaatcaattattttttctttctggatttttccaagttctacagagcgaaggctccaaagaagacagtact agggctgaggactaggtgggggatgccatctgtgtgggtggatagctggtctccctgggtgagctggaacgcagccccgt ggtacatcgagtgcagccagggttcctgcagccctggatacaccatcttctgggagctgaggagaggcacatggaagggg tactgggaggagaagagctggacctcatgggccaggtagagtggggaggaggtggccttgggagagtaggctttcccaga gaagaccacctgggagtagacgaagtagatgccactggtggggaccaggagagaattgttgctcaaggagaaaccatcct ggaggaaggcacggtccgtgtttgctctccagagcagtgagttctgcttgctggggtctcctaggaagagccatagggga tgggggtgggagatcaggggtctggatcagaggtctcaatccctgaggaagtgggcactgaacaactgagttcctggggg atggcagggggaggcataggagtgggctccctctgttttttttagcgtgggggaagttgggggagaggggtggatgcttg ggttcctgaggcaggggtaggaggagagctggtggggacatgtctgggaggtcaggtggatgtttaccaatgaggtgagc agcaggtttgagggtgctgtgggcaagatgcatcttggggtgctgacgggcagtctgggcagctgaaggtgtgaggccaa caccagggagcccctaggggagaacagagttgaggggggctctagggctcaaggtttggctgagccaccccagcagcccc cattctcctgctgcctcacctgggccccaggcagcagaaccagcagcagccccagaaggaggaggtgtagggtggtgcca cgcacccttgggaggaagagacgttcaggtggtgtcatggggagaacctgcagagaaagagagagagagagagagacagt gagcggggcggggcacgcggcggaagacagacctcccgccctgggagacagcaccccccgacccccgagagagagatcga cagagaaggggacaagatgcagtcagagaaaccccaaggtgagcagagggagacagagagagacaggaagggaacagaga ggaatcatggcagaaacagagaatgtgtgacagagacaatgagactgacagatggagagtcagagacagagaaggaaacc aaaaccaaacccaccaaggcccaggcccaggcaggccggggatccaggcagcaggtgcaggagggaccgaggcccaggca gagggcaggacactgcggggcggtagtccaaagcacgaagcacgggcagcccaaggagatggggcaggagagcctcacct gctgtgcggacccctgggcccggacgctcaggtccctttatagaggaagcggcagtggcagcgtggcaggcagcgggcgg gttctaggtcggggctggggcccggggaagcccccagggcttagaagatactgctgtttcagtcaaaggcaggaaaggct gaggcctaggagagaaccacaggctgggggttcaggcgactgagttctgggaaagggagtcgggtcaggggaatcgtggg ctgggagggccagggagtggggtcaggcctagagttccaaagaagggacagtcaattcagagaggaggcagttgagcagc tggggtgtgagctggaggcccggttccctgaagagcaatcatatataacatctctgcacccttggctgagtacaggcttc tctctttgcccatttccttctcttgtacccctgtccttgtcccaaacaactcaaatcatacttgtcccagtatacggact ttccagcccatctggcaggtttcacatcaagaaggtccattatatatccccttcatcggggacattctggtgtttgcctc ttgtccaggtgaaaatattaatggatcccccttccactcttgaaagtgtcctagtttggaagataaattttttggtcccc ttactcagagatgatgctggacagtcaagtatgatgaggtctcatctcactcctgaaggatgccctccatctcttcctga cttcaggtggcttccacagaacagatttatataaccccaaataaacacacattccaggatcaatgtggcagacaccttcc aaagttttctacaaaggaagtttgcagaattccacatgggtgaggcttaagggtggtgacttagggtggggtggggacag ctaagggacttgttctgaagctgcatttgcagagccaatacattattttaaaattgttccaggcctggtgcagtggctca cacctgtaatcctggcactttgggagtctgaggtgggcggattacttgaggtcaggagtttgagaccagctggccaacat ggtgaaaccccatctctataataaatacaaaaattagccaggcgtgctggtgcgcatctgcagtcccagctactcgggag gctgaggctggagaattatttgaacctgggaggcggaggctgcagtgagtcaagatcgcaccactgtattccagcctggg ggacagagcaagactctgtctcaaaaaaaaaaaaaaagtttccaaaatttttttcctttttattgatatgtaacttaggt atgaggtggacacctcttaagtgtacagctgatgaatttttccatctgtatgtagccaccacccagctccacgtattttc aggtccccagcaggttccctcatgccccctccctgctgataccctccaaagataaccaaccactctctcacttttatcac catagattatttcctcctggtttggggcatcatataaatgaaatcacacagaatgtactcatttctgtttgacttctttc agtcagcattatgtttgtgagattcatatacgtggttgtatgtatcagtaatgttttttaaaaaaattatgatgtaatat tctattgtatcaa at ttctaatatattctgttgatggggatttggtttgtttctagtttttgtctaacacaaaaatgt ctacacgaacattctcatacatgagcccatttcacttagcttgcaagttacaaggtttaaaaaaagcagtttctaaagat gactttattcacttttcctaagtttgagataataccaacttgtcacctcaaatattattactgctactcatgtgatttta cttggagagtgttagaggggttggagctggggctggtggtgacccggggtaaagcccactgttgcatggggcagaccact tctctccccaggcacaaggtccctgaggggtcttggtgtaacatggagggacatgtaagtaacattctgggtgtgtatga gctatttctcctgttcttctctacttgaggacctgcccctttgccttttatgctttactagtcttagctattatttctgt aggggcagaaaggggtgatcccttcctgacccatcataagggttatggccaatactcctataataaaagacagattaaca agagaaaagcataatacatttatttaatcaaagttttaggtgacatgggagccttcagaaatgaagacccaaggacccag gggaaaactatttttatgcttagatttgatgaagaatgaacagctgtgcagaaatgtaattgaacaaaaggagta catc taatggtcacagactgggactggggggatcccagcaaggcctggccatattcttcttggtctctctgtacagcattcctt cctcccaggtatagggcagaacctcttctggaatgagggtcttataacctactatcagatgagataagtcagaaaatttc ttttcctttttttttttttgagacagtttctcactgtcgcacaggctggagtgcagtggcacgatcttggctcactgcaa cctctgcctcccaggttcaagctattctcctgcctcagcctcccgagtagctgggattacaggcacacgccaccaagccc gccaaatttttttttgtatttttagtagagacggggtctcaccatgttggccaggttggtcttgaattcctgaccacagg tgacccaccagccttggcctcccaaagtgctgggattatgggcgtgagccactgcgcccaaccttcttctcattctttta accttattatctcttgtgtcagtgtgggtttcccttttagcccctgctcctttctttttctctgtgttgccctttctctc agggtcctttttgcttcctgttgtctctttctgcttctctaatggtatgagctgatggactgggaccccagctgagctat attaaaatataaaatgttattacaaggccaggagcagtggcacatgcctgtcatcccagcactttgggaggctgaggcga gcagatcacaaggtcaggagatagagacaatcctggctaatacggtgaaactccatcactgctaaaaatacaaaaaatta gccgagcatggtggcacgcgcctgtaatcctagctactagggaagctgaggcaggagaactgcttgaacccaggaggcgg aggttgcagtgagccgagatcgtgccactgccctccagcctgggcaacaaagtgagactccatttcaaacaaaccaacca aaaaacaaaacaaaacaaaacaagcaaacaaaaaaaggtattgcaattaacagtgagacacagagagaaatttaaattaa agaggaagaatgggacattgaaagacaaaaaagggaaggcaagaagggtgatggggagacatgagagacacagaggaagg aagggtaagactgggctgaggctcagtgtcacgtgcatgtgagatatgcgaaggatgctccttgagatgggccaatcttg gtttcaatctcagtttcggaggttgtatgaatttggtttctttcttggcaggccagcagttggtttgggactttccctgg gtgggagagctgatgactggagtcttgtgccccagactcagggaaatacagtctttatagtggtctttgtggagaaacta gtgaaatctctgaagcctccaaatgagactgaaatgacattagcttcaaacttgaacttagcctcaaaacctgaattggg atttaataccaacatcaaccctaacccaaatttaacctcaacccaaatcacaactcaaactcaaccccaactgtaaccct aacctcaaatctaaacacatcccaattaataaccccctaaataaaacttctcctctaccccaacccaaccctgtttctag ggctaatcttgaaaccagtttaccaccactcctaacactaaacttaaatctgactctaaatgtaagtccaatctgagcca caagcctaaagttgaactttatcctgctttatgaattattcatccattcctccatttagtgagtatctgcgtgcctaaca catgctgggcattgtcctaaggcaggagggacatggagggcaaagggatcagagaaggtaccagcacctgtggagcttgt attccagtgaggcccagacggaaaaagaaagaaacttgaaggaaggaaatttggtactatgagaaaataagacaggctga tgttgtaagagtggcagggagctacttttaaatacagtagtcagcaaaatcctctttgagtgtttgggtggcactggagc tgagacccaaatgacaaaaaatagtgaccaggtaaaagtttgggagcaaagcatttcaggtaaagggagcagctactgca aaggctggaaggcggaaccaagctgggggtgttgacgacaaacagaaggccagtgtggctggagcagagagagagactgg gaggcgggtgggagatgaggtcagagaggagggcaggggccaggtcatgcagggccatgcaagaagggtaaagcctctag atttcatccagccacaggaagcctttaaaggtcgtcagagtgtgtggtgcgtgcgtgtgtgtgtgtgtgtgtgtgttgca ggggagagaggnggagggagagagagagagagagaagagggaggtgagcagaggtgattggatttttttttcttttgaca tggtgtcttgctctgtggcctaggctggagtgcagtggcaccatcatagcccactgcaacctcaaaaccatgggctcaag tcatccttccacctcagcttcccaagtatctaggactacaggtgtgtgccactgtgcctggctaattttaaaaaatattt taaaatttttgttgagacagggtctatgctgctcaggctggtctcgaactcctggtttcaagtgatctgcccatcttggc ctcccaaagtttttttttgttagtttgagaggcggtttcgctcgttgcccaggctggagtgcaatgactgatctcatctc actgcaacctctgcctcctgggttcaagcgattctcctgcttcagcctcccaagtagctgggattacaggtgcatgccac cattcccggctaattttttgtatttagtagagatggggttcaccatgttagtcaggctgatctcaaactcctgacctcag gtgatccgcctgcctcagcctcccaaagttttgggattacaggtgtgagccaccatgctgggccagcctcccaaagtttt gggattacaggcatgagtcaccacactggccctggattttttttctttcttttttttggagacggagtctcactctgttg cccaggctggagtgcaatggcgtaatctcagctcactgcaacctctgctgcccgggttcaaacgattctcctgtcttagc ctcctgagtagctgggattataggtgcatgccaccatgcctggctaatttttgtacttttagtagagaaagtacaccatc ttggccaggctggtctcgaactcctgacctcaggtgatccacttgcgtcggcctcccaaagtgctgggattacaggcgtg agacaccgcacccagcctttttttttttttttttcttttaagacagaatcgctctgtcacccaggctggagtgcagtggc acaatctcggctcactgcaacctctgcctcccaggtttaagcaatccacctatgtcagtctcccaagtagctgggattat aggtgcatgtcaccatgcctggctaatttttgtacttttagtatagaaagtacaccatgttggccaggctggtcttgaac tcctgacctcaagtgatccgcctgcctcagcctcccgaagtgctggaattacagacatgtgccactgcacccggcctggt tttttttttctaagagatggagtctcacttttctgcccaggttggagtgcaatggcaccatcatagctcactgcagcctt caactcttggcctcaggcaatccttgcaccttagcctcgcaaagtgttgggattacaggcatgagccactgagccttgcc tggacttttttttttttttgagatggcgtctcgctctgttgcccaggttggagtgctacggcatgatcttggctcactgc aacttccacctcccaggttcaagcgattctcttg'cctcggccccccgagtagctgggattacagcatgcgccaccgtgcc tggctaattttggtatttttagtagagatagggtttcatcatgttgggcaggctggtcttgaactcctgacctcgtgatc cacccacctcggcctcccaaagtgctgggattataggcatagccaacgcgcccagcctggacttgtttttaaaagatcac tgtggctcctgtgtttaggctggctggtaggagacaggtggcagtgacattgatggtgaagagaaaatagtggcagccat ggagatggagagaagtagacaagtttgggatatattatacattccaggggtagaaacaacaggactagatgatggattga tgggtgggagatgtagatactgggagagaagcaggattctgatggatggaaaaactaaaaaattctattttgggtgtggt aagtctaagtctattagacatgcaagtagagatgtcactgggcagatacacatctggatttcaggggcaaggtccaagct agagaaagaaacctgggcatggtcagcatgaggatggtgtttaaagccatggaacttatcttgtgcatccctataagacc cctttgaggcacttgtttcccctcacaatggatgcagtgcatcttccattctgaattccagaggcaacaacctcctgctc ctagaagctaaactctccagacttagtcttctgaattcccactgggatttaacctccctggattcaattccctaccccac aaggacccttctaccaatccatttcacaatatttggtggaactcttcacattttcaaatcctgtcttctatgtttgaaag cattttcctctgggcattttgaaacctggctttcccctaatgatgctactcctctctgtggtgaaggttgctctttcttc gactccatcactaggggaatgaaggcagaagagaggggtcgttatcccctctcccccaggaccactgataaactcctcct catctcccaaagcacgtgccttctggatctgccatgctctccctgccttcacagcacaatcttatccatcaaaatattta ttatgctcttaacaacttgtataactagctcagtctttctccacatcttatccctaccatcatccttgtttgtttgtttt ttgagacaaggtattgctctgtcacccaggctggagtgcagtggcgtgatcttggctcactgcagcctcgacctcctggg ctcaagtgatcctcccacgtcagcctcctgagtagctaggactacaggcgcataccaccatgcccggctaagttttgtat ttttttttttttccagagatagggttttgctatgttgcctaggctggtcttgaactcctgagctcaagcaatccacccgc ctcagcctcccaaagtgctgggattacaggcatgacccaccgcacccggcctcctaccaccatctttagt (SEQ ID NO:12022) ttctccttctccccaacagttccccagggacctctctctaatcagccctctggcccaggcagtcagatcatcttctcgaa ccccgagtgacaagcctgtagcccatgttgtagcaaaccctcaagctgaggggcagctccagtggctgaaccgccgggcc aatgccctcctggccaatggcgtggagctgagagataaccagctggtggtgccatcagagggcctgtacctcatctactc ccaggtcctcttcaagggccaaggctgcccctccacccatgtgctcctcacccacaccatcagccgcatcgccgtctcct accagaccaaggtcaacctcctctctgccatcaagagcccctgccagagggagaccccagagggggctgaggccaagccc tggtatgagcccatctatctgggaggggtcttccagctggagaagggtgaccgactcagcgctgagatcaatcggcccga ctatctcgactttgccgagtctgggcaggtctactttgggatcattgccctgtgaggaggacgaacatccaaccttccca aacgcctcccctgccccaatccctttattaccccctccttcagacaccctcaacctcttctggctcaaaaagagaattgg gggcttagggtcggaacccaagcttagaactttaagcaacaagaccaccacttcgaaacctgggattcaggaatgtgtgg cctgcacagtgaattgctggcaaccactaagaattcaaactggggcctccagaactcactggggcctacagctttgatcc ctgacatctggaatctggagaccagggagcctttggttctggccagaatgctgcaggacttgagaagacctcacctagaa attgacacaagtggaccttaggccttcctctctccagatgtttccagacttccttgagacacggagcccagccctcccca tggagccagctccctc atttatgtttgcacttgtgattatttattatttat tatta ttatttatttacagatgaatg tatttatttgggagaccggggtatcctgggggacccaatgtaggagctgccttggctcagacatgttttccgtgaaaacg gagctgaacaataggctgttcccatgtagccccctggcctctgtgccttcttttgattatgttttttaaaatatttatct gattaagttgtctaaacaatgctgatttggtgaccaactgtcactcattgctgagcctctgctccccaggggagttgtgt ctgtaatcgccctactattcagtggcgagaaataaagtttgctttacgggccgggcactcccgagctgctgctcgagggc gccgagacggtgactccagtgctggacccggccaggagacaagggtacgggcctctctggtacacgagcgtggggttcgg cggcctggtgcagctccggaggggcgagagggtgtacgtcaacatcagtcaccccgatatggtggacttcgcgagaggga agaccttctttggggccgtgatggtggggtgagggaatatgagtgcgtggtgcgagtgcgtgaatattgggggnccggac gcccaggaccccatggcagtgggaaaaatgtaggagactgtttggaaattgattttgaacctgatgaaaataaagaatgg aaagcttcagtgctgccgataaagatgctgagttgcgacacacgtcttaattcagggtgggtgcacgggtgcgggttaaa tattctcagtactcttctggttgcttgaaacaattcatcacaacacagtgtatggcctttgctcctagggatgatggtct gcctgtcccaccccctccctgcctctgaatggccaggccccaccattagcccagttggagggtgggaggaagggggactt ctcaaactccgaagcttctctaggcatcctgattttcagggccacatggtcccaaccagactctgcaccatactcttttc tcttgggtaccccccaacagtgagaggggtcattacagagcccagcaagcaccactcagaaaggcccagcagcagagtaa gcccctatcatgacagaggaatgaagcctggaggggccccgcacttctccccctagagctgcctgaaggcctctctgtct cctacccgacagtcaactcttctcctccaaggagcttaattcaaggctcatggggtctgaagggaggaggctgaaggaga aagaaggggagaatattagagagagatggggatggcaggaaggagcctgtggtgcctgaaaacaccaggaagttctgggg aggaggaaaaaccgatgccccacttagggtgtcccatttagggtgagacggaaaatcctcacctttttttcacactttag gtcccccttcccaaaagtgagtaagtgtgggtgcttctgggatgagtaacagtgtcccccattacttcatggctgacttt cagccacaggctggaggaggcagagggtgacccaaggccctatctaggtcaccccaatgggtcaccctaccccctcagcc taccacatggttttctcctgcctggcaccccagggctggaggtaaagcctaattttccgaacttcagttggggctcccag tctaggggggctcaatttccgtctccatattttgttttggaattattatttttttgagacagggtctcgttctgtcaccc agacgggggtacagtggcatgatcatagcttactgtaacctcaaactcctgggcttgagtgatcctcctgcctcagcctc ctgaggagctaggattacaggcatgcaccactacacctgactaatctttaattttttttctagaaacaaggtcttgctat gttgcacaggctggtcttgaactagtgggctcaagtggtcctcccacctcagcctcccaaagtgttgggataacaggcat gagccactgcgccccacccttatttgtctttgactctctccagaagagccttcatccagggagggggtgcttttctcttt ccggattacccacctctcacctctcccctccttcaccacaaagaccagtgggaccaagccggcatgtgagtccttcaccc acatcttattcctatgtttcattcttttttaaaaaatagagacaggatctcactatgttgcccaggttgctctggaactc ctgggttcaagcgatcctctcaccttggccttgcaaagtggtaggattacaggtgcatgccaccacgtccggcagttcgg ttccttgttctttattgtcctcagtctcttcgatttcacccactgagagaatggaaggggatagaacagctggaaactgg ttgaaggaagccagaattcactaagtgcccactgtgccaagggctgagtgaggtcctctgatggaggtcaggccttctct cacatgccctatgtgtggtggacattcctatccccattggatagataggttaagtggctggttcaggttgcagagttagg acagggtgatttgaagcctag'acacccgaatctctggaagtcccttggctgtgtgattcaggtacctgagaatgcggctc ctctccagctctctccggactgctggccagctgcaacagccggaaatctcacctgagctgcaggattttcccagcaagga ttggaattcccagagttggaaattcccatgccctgagggagaggtaattaggttcaggctcttgtttcctgggggatggg gaatattctgttgggctttgtttatgtagggtctccagggccctaggagtctaaggatgggactgggtccgagggatctt aaagcctgtggagagaggacttagggagcttcttcccacccacaagaagaggcagatgcagaattaattccaagaaggag accatgtttcttttctaagcaaactttatttctcgccactgaatagtagggcgattacagacacaactccctggggagca gaggcctcagcaatgagtgacagttggtcaccaaatcagcattgtttagacaacttaatcagataatattttaaaaaaca taatcaaaagaaggcacagaggccagggggctacatgggaacagcctattgttcagcctccgttttcacggaaaacatgt ctgagccaaggcagctcctacattgggtcccccaggataccccggtctcccaaataaatacattcatctgtaaataaata aataataaataaataataaataatcacaagtgcaaacataaatagagggagctggctccatggggagggctgggctccgt gtctcaaggaagtctggaaacatctggagagaggaaggcctaaggtccacttgtgtcaatttctaggtgaggtcttctca agtcctgcagcattctggccagaaccaaaggctccctggtctccagattccagatgtcagggatcaaagctgtaggcccc agtgagttctggaggccccagtttgaattcttagtggttgccagcacttcactgtgcaggccacacattcctgaatccca ggtttcgaagtggtggtcttgttgcttaaagttctaagcttgggttccgaccctaagcccccaattctctttttgagcca gaagaggttgagggtgtctgaaggagggggtaataaagggattggggcaggggaggcgtttgggaaggttggatgttcgt cctcctcacagggcaatgatcccaaagtagacctgcccagactcggcaaagtcgagatagtcgggccgattgatctcagc gctgagtcggtcacccttctccagctggaagacccctcccagatagatgggctcataccagggcttggcctcagccccct ctggggtctccctctggcaggggctcttgatggcagagaggaggttgaccttggtctggtaggagacggcgatgcggctg atggtgtgggtgaggagcacatgggtggaggggcagccttggcccttgaagaggacctgggagtagatgaggtacaggcc ctctgatggcaccaccagctggttatctctcagctccacgccattggccaggagggcattggcccggcggttcagccact ggagctgcccctcagcttgagggtttgctggagggagggagagagggagaggagagtcagtgtggccatgtcggttcact ctccacatcctggccctcgagctctgcccaccccacatccggttcctgtcctctctgtctgtcatcccacatcccacctg gccatgacgttctgagtatcccactaaggcctgtgctgttcctccacccttcccttgagctcagcgagtccttctcacat tgtctccaagttctgcctaccatcagccgggcttcaatccccaaatcctagccctccaagttccaagacacatcctcaga gctcttacctacaacatgggctacaggcttgtcactcggggttcgagaagatgatcctgaagaggagagagaaaagaaaa agctgagacccttaaacttcctagaaaatacccccctactttcacctccatccatcctcccccaagaccaaaactttaaa tttcccccactgctttccataccggtactaaccctaccccccaaacccaaacccagaattaggaaagaggtttggagaca cttactgactgcctgggccagagggctgattagagagaggtccctggggaactgttggggagaaggagaatggttaacat cgagggagtcacccttaaaggaggaacagctggctgcctgtctggcctgcgctcttagccctgaggtgtctggttttctc tctccattcatctgtgtattcaccttccaggcattcaacagctctttccctgagtgtcttctgtgtgccagacaccctat cttcttctctccttatctcccccatctctctccttagctgtcatatttcccgctctttctgtctcaccatctttattcat atcacttgtttcttcccccatctctcttctcacaccccacatctgtctccatatcttatttatatatctgcttgttcatt cattcattcattcattcactccatacacacttagtgagcaccttccatgtgccagacatcctgtctctccatctttctct ctctctcttccccatctcttgccacatctctttctgcatccccgtctttctccacgtttttttctctccatccctcccta tcagcgcacatctttcacccatcccatctctctccctctcttgcgtctccatttccccttgggtgggagagtggatgaag gctggccaggcactcacctcttccctctgggggccgatcactccaaagtgcagcaggcagaagagcgtggtggcgcctgc cacgatcaggaaggagaagaggctgaggaacaagcaccgcctggagccctggggcccccctgtcttcttggggagcgcct cctcggccagctccacgtcccggatcatgctttcagtgctcatggtgtcctttccaggggagagagggtggagccgtggg tcagtatgtgagaggaagag^'aacctgcctggcagcttgtcaggggatgtggcgtctgagggttgttttcagggggggtct gtagttgcttctctccctcttagctggtcctctgctgtccttgctgagggagcgtctgctggctgggtgtgccaacaact gcctttatatgtccctggggcgagaggagggcggggaaagaatcattcaaccagcggaaaacttccttggtggagaaacc catgagctcatctggaggaagcggtagtgggccctgcaccttctgtctcggtttcttctccatcgcgggggcggggattt ggaaagttggggacacacaagcatcaaggatacccctcacactccccatcctccctgctccgattccgaggggggtcttc tgggccactgactgatttgtgtgtaggaccctggaggctgaaccccgtccccatgcccctcaaaacctattgcctccatt tcttttggggaccaggtctgtggtctgtttccttctaacttccagacaggatgcaggaaaaagatagaactagaactggg aggggcttcagaaagctgagtccgttgagggagagaaaacggggttggagggaaaagctgtgttgagtcctgaggcctgt gtttgggccctgcggggagaaggagctgggggcttggtggcaggcttgaggcctcaggaaaggctgggtgcgggtagcag ggacaagcctgggacagccccggggagtgaaatcacccccgggaattcacagaccccactggggcaggccctcttctttc attctgacccggagactcataatgcttggttcagtcttggcttccaaggaactctggggtccctgatttttttcatgaag ctctcacttctcagggccccagtgtgtggccatatcttcttaaacgtcccctgtattccatacctggaggtcctggaggc tctttcactccctggggccctctacatggccctgtcttcgttaagtgggggtccccatactcgacttccatagccctgga cattctcctacccattgctgtggtcacatctccccagaggtctcctgtaacccattcctcagagccgctacatgtggcca tatctcccaggagctccctgacccccgcccctccagaccctgacttttccttcgtcttctcagcttctcctttgcttccc ctgcagcagtctggcggcctcacctggtgagtccatcacatatccctgaagctctctgagcccttatccttttgttctcc ccacagctcttgctccctttgagccctctgtccctccctccattccttagatagactgggaagttctcactcccagacac acacacacaagcagacagcatttcagagaaaagaggtttattgggcttcatcgagggtgcagatgcctccgtgtggggct ctggtcggcagctggctttcagagcctttccctgccttctggggccctgtgatccctcatgcctacttctttctctcttg gtcagccttgtgcgcatgccctctcactcttcatctcttgggcctgtctctgtttctccttggatgttcttctattattc ccctctctccatcctccataaataaataatttaatttttttgccttcataaatagtcccctccctgcctctagtcatccc ccaagctcctccatgtgcctgctcttcctctgtgtgtggatctaggccccacctagctggtgggacagaccaacagcttt gggctgggaattcctaggcaggcttgaaatcctcagccagacagacatcagggatggttcagggaggtgtggtcccctgg gatgcctagaattccttctttgaaagctccggtgacttgatcagggaagacttgagctgttggaatggccaaaggagagg tggtgacgacccctgaaatggtcagaatggaggcagaatggggagaaggtcttgaaatcaattattttttctttctggat ttttccaagttctacagagcgaaggctccaaagaagacagtactagggctgaggactaggtgggggatgccatctgtgtg ggtggatagctggtctccctgggtgagctggaacgcagccccgtggtacatcgagtgcagccagggttcctgcagccctg gatacaccatcttctgggagctgaggagaggcacatggaaggggtactgggaggagaagagctggacctcatgggccagg tagagtggggaggaggtggccttgggagagtaggctttcccagagaagaccacctgggagtagacgaagtagatgccact ggtggggaccaggagagaattgttgctcaaggagaaaccatcctggaggaaggcacggtccgtgtttgctctccagagca gtgagttctgcttgctggggtctcctaggaagagccataggggatgggggtgggagatcaggggtctggatcagaggtct caatccctgaggaagtgggcactgaacaactgagttcctgggggatggcagggggaggcataggagtgggctccctctgt tttttttagcgtgggggaagttgggggagaggggtggatgcttgggttcctgaggcaggggtaggaggagagctggtggg gacatgtctgggaggtcaggtggatgtttaccaatgaggtgagcagcaggtttgagggtgctgtgggcaagatgcatctt ggggtgctgacgggcagtctgggcagctgaaggtgtgaggccaacaccagggagcccctaggggagaacagagttgaggg gggctctagggctcaaggtttggctgagccaccccagcagcccccattctcctgctgcctcacctgggccccaggcagca gaaccagcagcagccccagaaggaggaggtgtagggtggtgccacgcacccttgggaggaagagacgttcaggtggtgtc atggggagaacctgcagagaaagagagagagagagagagacagtgagcggggcggggcacgcggcggaagacagacctcc cgccctgggagacagcaccccccgacccccgagagagagatcgacagagaaggggacaagatgcagtcagagaaacccca aggtgagcagagggagacagagagagacaggaagggaacagagaggaatcatggcagaaacagagaatgtgtgacagaga caatgagactgacagatggagagtcagagacagagaaggaaaccaaaaccaaacccaccaaggcccaggcccaggcaggc cggggatccaggcagcaggtgcaggagggaccgaggcccaggcagagggcaggacactgcggggcggtagtccaaagcac gaagcacgggcagcccaaggagatggggcaggagagcctcacctgctgtgcggacccctgggcccggacgctcaggtccc tttatagaggaagcggcagtggcagcgtggcaggcagcgggcgggttctaggtcggggctggggcccggggaagccccca gggcttagaagatactgctgtttcagtcaaaggcaggaaaggctgaggcctaggagagaaccacaggctgggggttcagg cgactgagttctgggaaagggagtcgggtcaggggaatcgtgggctgggagggccagggagtggggtcaggcctagagtt ccaaagaagggacagtcaattcagagaggaggcagttgagcagctggggtgtgagctggaggcccggttccctgaagagc aatcatatataacatctctgcacccttggctgagtacaggcttctctctttgcccatttccttctcttgtacccctgtcc ttgtcccaaacaactcaaatcatacttgtcccagtatacggactttccagcccatctggcaggtttcacatcaagaaggt ccattatatatcccc tcatcggggacattctggtgtttgcctcttgtccaggtgaaaatattaatggatcccccttcca ctcttgaaagtgtcctagtttggaagataaattttttggtccccttactcagagatgatgctggacagtcaagtatgatg aggtctca ctcactcctgaaggatgccctccatctcttcctgacttcaggtggcttccacagaacagatttatataacc ccaaataaacacacattccaggatcaatgtggcagacaccttccaaagttttctacaaaggaagtttgcagaattccaca tgggtgaggcttaagggtggtgacttagggtggggtggggacagctaagggacttgttctgaagctgcatttgcagagcc aatacattattttaaaattgttccaggcctggtgcagtggctcacacctgtaatcctggcactttgggagtctgaggtgg gcggattacttgaggtcaggagtttgagaccagctggccaacatggtgaaaccccatctctataataaatacaaaaatta gccaggcgtgctggtgcgcatctgcagtcccagctactcgggaggctgaggctggagaattatttgaacctgggaggcgg aggctgcagtgagtcaagatcgcaccactgtattccagcctgggggacagagcaagactctgtctcaaaaaaaaaaaaaa agtttccaaaatttttttcctttttattgatatgtaacttaggtatgaggtggacacctcttaagtgtacagctgatgaa tttttccatctgtatgtagccaccacccagctccacgtattttcaggtccccagcaggttccctcatgccccctccctgc tgataccctccaaagataaccaaccactctctcacttttatcaccatagattatttcctcctggtttggggcatcatata aatgaaatcacacagaatgtactcatttctgtttgacttctttcagtcagcattatgtttgtgagattcatatacgtggt tgtatgtatcagtaatgttttttaaaaaaattatgatgtaatattctattgtatcaatatattctaatatattctgttga tggggatttggtttgtttctagtttttgtctaacacaaaaatgtctacacgaacattctcatacatgagcccatttcact tagcttgcaagttacaaggtttaaaaaaagcagtttctaaagatgactttattcacttttcctaagtttgagataatacc aacttgtcacctcaaatattattactgctactcatgtgattttacttggagagtgttagaggggttggagctggggctgg tggtgacccggggtaaagcccactgttgcatggggcagaccacttctctccccaggcacaaggtccctgaggggtcttgg tgtaacatggagggacatgtaagtaacattctgggtgtgtatgagctatttctcctgttcttctctacttgaggacctgc ccctttgccttttatgctttactagtcttagctattatttctgtaggggcagaaaggggtgatcccttcctgacccatca taagggttatggccaatactcctataataaaagacagattaacaagagaaaagcataatacatttatttaatcaaagttt taggtgacatgggagccttcagaaatgaagacccaaggacccaggggaaaactatttttatgcttagatttgatgaagaa tgaacagctgtgcagaaatgtaattgaacaaaaggagtatcatctaatggtcacagactgggactggggggatcccagca aggcctggccatattcttcttggtctctctgtacagcattccttcctcccaggtatagggcagaacctcttctggaatga gggtcttataacctactatcagatgagataagtcagaaaatttcttttcctttttttttttttgagacagtttctcactg tcgcacaggctggagtgcagtggcacgatcttggctcactgcaacctctgcctcccaggttcaagctattctcctgcctc agcctcccgagtagctgggattacaggcacacgccaccaagcccgccaaatttttttttgtatttttagtagagacgggg tctcaccatgttggccaggttggtcttgaattcctgaccacaggtgacccaccagccttggcctcccaaagtgctgggat tatgggcgtgagccactgcgcccaaccttcttctcattcttttaacctta tatctcttgtgtcagtgtgggtttccctt ttagcccctgctcctttctttttctctgtgttgccctttctctcagggtcctttttgcttcctgttgtctctttctgctt ctctaatggtatgagctgatggactgggaccccagctgagctatattaaaatataaaatgttattacaaggccaggagca gtggcacatgcctgtcatcccagcactttgggaggctgaggcgagcagatcacaaggtcaggagatagagacaatcctgg ctaatacggtgaaactccatcactgctaaaaatacaaaaaattagccgagcatggtggcacgcgcctgtaatcctagcta ctagggaagctgaggcaggagaactgcttgaacccaggaggcggaggttgcagtgagccgagatcgtgccactgccctcc agcctgggcaacaaagtgagactccatttcaaacaaaccaaccaaaaaacaaaacaaaacaaaacaagcaaacaaaaaaa ggtattgcaattaacagtgagacacagagagaaatttaaattaaagaggaagaatgggacattgaaagacaaaaaaggga aggcaagaagggtgatggggagacatgagagacacagaggaaggaagggtaagactgggctgaggctcagtgtcacgtgc atgtgagatatgcgaaggatgctccttgagatgggccaatcttggtttcaatctcagtttcggaggttgtatgaatttgg tttctttcttggcaggccagcagttggtttgggactttccctgggtgggagagctgatgactggagtcttgtgccccaga ctcagggaaatacagtctttatagtggtctttgtggagaaactagtgaaatσtctgaagcctccaaatgagactgaaatg acattagcttcaaacttgaacttagcctcaaaacctgaattgggatttaataccaacatcaaccctaacccaaatttaac ctcaacccaaatcacaactcaaactcaaccccaactgtaaccctaacctcaaatctaaacacatcccaattaataacccc ctaaataaaacttctcctctaccccaacccaaccctgtttctagggctaatcttgaaaccagtttaccaccactcctaac actaaacttaaatctgactctaaatgtaagtccaatctgagccacaagcctaaagttgaactttatcctgctttatgaat tattcatccattcctccatttagtgagtatctgcgtgcctaacacatgctgggcattgtcctaaggcaggagggacatgg agggcaaagggatcagagaaggtaccagcacctgtggagcttgtattccagtgaggcccagacggaaaaagaaagaaact tgaaggaaggaaatttggtactatgagaaaataagacaggctgatgttgtaagagtggcagggagctacttttaaataca gtagtcagcaaaatcctctttgagtgtttgggtggcactggagctgagacccaaatgacaaaaaatagtgaccaggtaaa agtttgggagcaaagcatttcaggtaaagggagcagctactgcaaaggctggaaggcggaaccaagctgggggtgttgac gacaaacagaaggccagtgtggctggagcagagagagagactgggaggcgggtgggagatgaggtcagagaggagggcag gggccaggtcatgcagggccatgcaagaagggtaaagcctctagatttcatccagccacaggaagcctttaaaggtcgtc agagtgtgtggtgcgtgcgtgtgtgtgtgtgtgtgtgtgttgcaggggagagaggnggagggagagagagagagagagaa gagggaggtgagcagaggtgattggatttttttttcttttgacatggtgtcttgctctgtggcctaggctggagtgcagt ggcaccatcatagcccactgcaacctcaaaaccatgggctcaagtcatccttccacctcagcttcccaagtatctaggac tacaggtgtgtgccactgtgcctggctaattttaaaaaatattttaaaatttttgttgagacagggtctatgctgctcag gctggtctcgaactcctggtttcaagtgatctgcccatcttggcctcccaaagtttttttttgttagtttgagaggcggt ttcgctcgttgcccaggctggagtgcaatgactgatctcatctcactgcaacctctgcctcctgggttcaagcgattctc ctgcttcagcctcccaagtagctgggattacaggtgcatgccaccattcccggctaattttttgtatttagtagagatgg ggttcaccatgttagtcaggctgatctcaaactcctgacctcaggtgatccgcctgcctcagcctcccaaagttttggga ttacaggtgtgagccaccatgctgggccagcctcccaaagttttgggattacaggcatgagtcaccacactggccctgga ttttttttctttcttttttttggagacggagtctcactctgttgcccaggctggagtgcaatggcgtaatctcagctcac tgcaacctctgctgcccgggttcaaacgattctcctgtcttagcctcctgagtagctgggattataggtgcatgccacca tgcctggctaatttttgtacttttagtagagaaagtacaccatcttggccaggctggtctcgaactcctgacctcaggtg atccacttgcgtcggcctcccaaagtgctgggattacaggcgtgagacaccgcacccagcctttttttttttttttttct tttaagacagaatcgctctgtcacccaggctggagtgcagtggcacaatctcggctcactgcaacctctgcctcccaggt ttaagcaatccacctatgtcagtctcccaagtagctgggattataggtgcatgtcaccatgcctggctaatttttgtact tttagtatagaaagtacaccatgttggccaggctggtcttgaactcctgacctcaagtgatccgcctgcctcagcctccc gaagtgctggaattacagacatgtgccactgcacccggcctggttttttttttctaagagatggagtctcacttttctgc ccaggttggagtgcaatggcaccatcatagctcactgcagccttcaactcttggcctcaggcaatccttgcaccttagcc tcgcaaagtgttgggattacaggcatgagccactgagccttgcctggacttttttttttttttgagatggcgtctcgctc tgttgcccaggttggagtgctacggcatgatcttggctcactgcaacttccacctcccaggttcaagcgattctcttgcc tcggccccccgagtagctgggattacagcatgcgccaccgtgcctggctaattttggtatttttagtagagatagggttt catcatgttgggcaggctggtcttgaactcctgacctcgtgatccacccacctcggcctcccaaagtgctgggattatag gcatagccaacgcgcccagcctggacttgtttttaaaagatcactgtggctcctgtgtttaggctggctggtaggagaca ggtggcagtgacattgatggtgaagagaaaatagtggcagccatggagatggagagaagtagacaagtttgggatatatt atacattccaggggtagaaacaacaggactagatgatggattgatgggtgggagatgtagatactgggagagaagcagga ttctgatggatggaaaaactaaaaaattctattttgggtgtggtaagtctaagtctattagacatgcaagtagagatgtc actgggcagatacacatctggatttcaggggcaaggtccaagctagagaaagaaacctgggcatggtcagcatgaggatg gtgtttaaagccatggaacttatcttgtgcatccctataagacccctttgaggcacttgtttcccctcacaatggatgca gtgcatcttccattctgaattccagaggcaacaacctcctgctcctagaagctaaactctccagacttagtcttctgaat tcccactgggatttaacctccctggattcaattccctaccccacaaggacccttctaccaatccatttcacaatatttgg tggaactcttcacattttcaaatcctgtcttctatgtttgaaagcattttcctctgggcattttgaaacctggctttccc ctaatgatgctactcctctctgtggtgaaggttgctctttcttcgactccatcactaggggaatgaaggcagaagagagg ggtcgttatcccctctcccccaggaccactgataaactcctcctcatctcccaaagcacgtgccttctggatctgccatg ctctccctgccttcacagcacaatcttatccatcaaaatatttattatgctcttaacaacttgtataactagctcagtct ttctccacatcttatccctaccatcatccttgtttgtttgttttttgagacaaggtattgctctgtcacccaggctggag tgcagtggcgtgatcttggctcactgcagcctcgacctcctgggctcaagtgatcctcccacgtcagcctcctgagtagc taggactacaggcgcataccaccatgcccggctaagttttgtatttttttttttttccagagatagggttttgctatgtt gcctaggctggtcttgaactcctgagctcaagcaatccacccgcctcagcctcccaaagtgctgggattacaggcatgac ccaccgcacccggcctcctaccaccatctttagt (SEQ ID NO: 12023) aattcgataattcaaaatgatatttcagtggggacaaggccaaaccatattatgtgctttatgctactaataaaaaggtt aaaccgaacaagttcaaagacaaaactcagtagtactttattcagacaggttagtctaaatctgttaaccttatacttgc aactctgatcattcattaattctgcaaattttaataaatgctttattttaagctaaatgctgagatgaaaaaatgaaacc atatgagttagcaaagtagaaaatataggcatattaatcagtaaatgcagaatgataaatgctccatcaatatgcacttg ttgtagtgaggccaccgaggagggtgcaatcctctcaacctgggaggagcaggtaggacttcagatgtcatccaactcaa agatatagtgagggacttgatcaaacatttgccaagaccactatgagttaaatgaatagattaggcatttctccaatgtt gcaagcttcgaatcatatccaaactcagaacaacatagcttggtcataatgatcccaaggatcctattggccattgtctt tgagcctcaaaggaacatattaaaactccataatacccttttgatctattctgaagttaagtagtgaatttacatgatga tgacacaaacactgtaaaggacctctgggttacttgtttataagctagtatttcctgaatcaatttttctgatccctaga tatttggtaggtgaagtcatacctatatatccccacaccctagaacagcatctccaacttttttttccctccttgtcttt tagtgggagccacatcagtatccaaggaggagatccagaagcctctccaaccaggtagggacagttatagattccagacc tcagctatggcctttgttacagagtacaaatgttatatagtacaagtttattgtacacatcccattgagtctctgagctt tagaattttcttgtagaatttaacagttttttcatgccgtatttacatattattgctagtatttagaattttcttctcca aatgtataacgtttattattgcattttttgtatccactaagtggaaaatcatgcattagatattgtagaagtagatacaa caatgaacaagaactggtcctgaccatgagaggaactgatgatccaatgggggagatagacctgcacgtgtttaataaaa ggaagtggctattccggtttctttttgatgggcaagcattttgcaaggccttgggctatgtgtgtgcaaggctaagccag ttagttaattgggatttttttaaaaaggcacttcactggggggaaaaggaacatagagttggttattgtccccttgccta taataaaaacctattatttttaattttttaactgggtttgcggttaaatctcacagcccaagagatttgccacttcagat ggattccatacacttgcatttaagtatgcaaaaaaattccaattatccagcaatttaaccaaattattggtaacttttct aaaacaaaaaaaaattgtttcccttgttttggcagcaatttcagttacagtcctttactttctactcaagaaaatagttt caaaaagttgatgtttgttgctaaaagaactatttttatgaataaatataaaactaagaagttatggtgtccctttttta aaaaatgactcatcaaaagaaataactttttcctttctcttgtaagagaaaaaaattaatctcttttagaattgcaaaca tatttccttgatggagaaaatcaattcacatggcatagtcgttatttatccagttcaaaaaccagagtagaatttactac tctgtctccattttttctctccccacccccttaacccacattggattcagaaagcttcattctgcaatcagcattgtcct ttatctttccagtaaagatagccttttggagtcgaagatgaggaaaagcctgtattttatagtcttggaagtgtcttctt ttgccaggacagagagaggagcttcagcagtgagagcaactgaaggggttaatagtggaacttggctgggtgtctgttaa acttttttccctggctctgccctgggtttccccttgaagggatttccctccgcctctgcaacaagaccctttataaagca cagactttctatttcactccgcggtatctgcatcgggcctcactggcttcaggagctgaataccctcccaggcacacaca ggtgggacacaaataagggttttggaaccactattttctcatcacgacagcaacttaaaatgcctgggaagatggtcgtg atccttggagcctcaaatatactttggataatgtttgcagcttgtaagttatttcccttcatctgtttcaaatgtt (SEQ ID NO: 12024) atgcctgggaagatggtcgtgatccttggagcctcaaatatactttggataatgtttgcagcttctcaagcttttaaaat cgagaccaccccagaatctagatatcttgctcagattggtgactccgtctcattgacttgcagcaccacaggctgtgagt ccccatttttctcttggagaacccagatagatagtccactgaatgggaaggtgacgaatgaggggaccacatctacgctg acaatgaatcctgttagttttgggaacgaacactcttacctgtgcacagcaacttgtgaatctaggaaattggaaaaagg aatccaggtggagatctactcttttcctaaggatccagagattcatttgagtggccctctggaggctgggaagccgatca cagtcaagtgttcagttgctgatgtatacccatttgacaggctggagatagacttactgaaaggagatcatctcatgaag agtcaggaatttctggaggatgcagacaggaagtccctggaaaccaagagtttggaagtaacctttactcctgtcattga ggatattggaaaagttcttgtttgccgagctaaattacacattgatgaaatggattctgtgcccacagtaaggcaggctg taaaagaattgcaagtctacatatcacccaagaatacagttatttctgtgaatccatccacaaagctgcaagaaggtggc tctgtgaccatgacctgttccagcgagggtctaccagctccagagattttctggagtaagaaattagataatgggaatct acagcacctttctggaaatgcaactctcaccttaattgctatgaggatggaagattctggaatttatgtgtgtgaaggag ttaatttgattgggaaaaacagaaaagaggtggaattaattgttcaagagaaaccatttactgttgagatctcccctgga ccccggattgctgctcagattggagactcagtcatgttgacatgtagtgtcatgggctgtgaatccccatctttctcctg gagaacccagatagacagccctctgagcgggaaggtgaggagtgaggggaccaattccacgctgaccctgagccctgtga gttttgagaacgaacactcttatctgtgcacagtgacttgtggacataagaaactggaaaagggaatccaggtggagctc tactcattccctagagatccagaaatcgagatgagtggtggcctcgtgaatgggagctctgtcactgtaagctgcaaggt tcctagcgtgtacccccttgaccggctggagattgaattacttaagggggagactattctggagaatatagagtttttgg aggatacggatatgaaatctctagagaacaaaagtttggaaatgaccttcatccctaccattgaagatactggaaaagct cttgtttgtcaggctaagttacatattgatgacatggaattcgaacccaaacaaaggcagagtacgcaaacactttatgt caatgttgcccccagagatacaaccgtcttggtcagcccttcctccatcctggaggaaggcagttctgtgaatatgacat gcttgagccagggctttcctgctccgaaaatcctgtggagcaggcagctccctaacggggagctacagcctctttctgag aatgcaactctcaccttaatttctacaaaaatggaagattctggggtttatttatgtgaaggaattaaccaggctggaag aagcagaaaggaagtggaattaattatccaagttactccaaaagacataaaacttacagcttttccttctgagagtgtca aagaaggagacactgtcatcatctcttgtacatgtggaaatgttccagaaacatggataatcctgaagaaaaaagcggag acaggagacacagtactaaaatctatagatggcgcctataccatccgaaaggcccagttgaaggatgcgggagtatatga atgtgaatctaaaaacaaagttggctcacaattaagaagtttaacacttgatgttcaaggaagagaaaacaacaaagact atttttctcctgagcttctcgtgctctattttgcatcctccttaataatacctgccattggaatgataatttactttgca agaaaagccaacatgaaggggtcatatagtcttgtagaagcacagaaatcaaaagtgtag (SEQ ID NO: 12025) aattcgataattcaaaatgatatttcagtggggacaaggccaaaccatattatgtgctttatgctactaataaaaaggtt aaaccgaacaagttcaaagacaaaactcagtagtactttattcagacaggttagtctaaatctgttaaccttatacttgc aactctgatcattcattaattctgcaaattttaataaatgctttattttaagctaaatgctgagatgaaaaaatgaaacc atatgagttagcaaagtagaaaatataggcatattaatcagtaaatgcagaatgataaatgctccatcaatatgcacttg ttgtagtgaggccaccgaggagggtgcaatcctctcaacctgggaggagcaggtaggacttcagatgtcatccaactcaa agatatagtgagggacttgatcaaacatttgccaagaccactatgagttaaatgaatagattaggcatttctccaatgtt gcaagcttcgaatcatatccaaactcagaacaacatagcttggtcataatgatcccaaggatcctattggccattgtctt tgagcctcaaaggaacatattaaaactccataatacccttttgatctattctgaagttaagtagtgaatttacatgatga tgacacaaacactgtaaaggacctctgggttacttgtttataagctagtatttcctgaatcaatttttctgatccctaga tatttggtaggtgaagtcatacctatatatccccacaccctagaacagcatctccaacttttttttccctccttgtcttt tagtgggagccacatcagtatccaaggaggagatccagaagcctctccaaccaggtagggacagttatagattccagacc tcagctatggcctttgttacagagtacaaatgttatatagtacaagtttattgtacacatcccattgagtctctgagctt tagaattttcttgtagaatttaacagttttttcatgccgtatttacatattattgctagtatttagaattttcttctcca aatgtataacgtttattattgcattttttgtatccactaagtggaaaatcatgcattagatattgtagaagtagatacaa caatgaacaagaactggtcctgaccatgagaggaactgatgatccaatgggggagatagacctgcacgtgtttaataaaa ggaagtggctattccggtttctttttgatgggcaagcattttgcaaggccttgggctatgtgtgtgcaaggctaagccag ttagttaattgggatttttttaaaaaggcacttcactggggggaaaaggaacatagagttggttattgtccccttgccta taataaaaacctattatttttaattttttaactgggtttgcggttaaatctcacagcccaagagatttgccacttcagat ggattccatacacttgcatttaagtatgcaaaaaaattccaattatccagcaatttaaccaaattattggtaacttttct aaaacaaaaaaaaattgtttcccttgttttggcagcaatttcagttacagtcctttactttctactcaagaaaatagttt caaaaagttgatgtttgttgctaaaagaactatttttatgaataaatataaaactaagaagttatggtgtccctttttta aaaaatgactcatcaaaagaaataactttttcctttctcttgtaagagaaaaaaattaatctcttttagaattgcaaaca tatttccttgatggagaaaatcaattcacatggcatagtcgttatttatccagttcaaaaaccagagtagaatttactac tctgtctccattttttctctccccacccccttaacccacattggattcagaaagcttcattctgcaatcagcattgtcct ttatctttccagtaaagatagccttttggagtcgaagatgaggaaaagcctgtattttatagtcttggaagtgtcttctt ttgccaggacagagagaggagcttcagcagtgagagcaactgaaggggttaatagtggaacttggctgggtgtctgttaa acttttttccctggctctgccctgggtttccccttgaagggatttccctccgcctctgcaacaagaccctttataaagca cagactttctatttcactccgcggtatctgcatcgggcctcactggcttcaggagctgaataccctcccaggcacacaca ggtgggacacaaataagggttttggaaccac attttctcatcacgacagcaacttaaaatgcctgggaagatggtcgtg atccttggagcctcaaatatactttggataatgtttgcagcttgtaagttatttcccttcatctgtttcaaatgttatgc ctgggaagatggtcgtgatccttggagcctcaaatatactttggataatgtttgcagcttctcaagcttttaaaatcgag accaccccagaatctagatatcttgctcagattggtgactccgtctcattgacttgcagcaccacaggctgtgagtcccc atttttctcttggagaacccagatagatagtccactgaatgggaaggtgacgaatgaggggaccacatctacgctgacaa tgaatcctgttagttttgggaacgaacactcttacctgtgcacagcaacttgtgaatctaggaaattggaaaaaggaatc caggtggagatctactcttttcctaaggatccagagattcatttgagtggccctctggaggctgggaagccgatcacagt caagtgttcagttgctgatgtatacccatttgacaggctggagatagacttactgaaaggagatcatctcatgaagagtc aggaatttctggaggatgcagacaggaagtccctggaaaccaagagtttggaagtaacctttactcctgtcattgaggat attggaaaagttcttgtttgccgagctaaattacacattgatgaaatggattctgtgcccacagtaaggcaggctgtaaa agaattgcaagtctacatatcacccaagaatacagttatttctgtgaatccatccacaaagctgcaagaaggtggctctg tgaccatgacctgttccagcgagggtctaccagctccagagattttctggagtaagaaattagataatgggaatctacag cacctttctggaaatgcaactctcaccttaattgctatgaggatggaagattctggaatttatgtgtgtgaaggagttaa tttgattgggaaaaacagaaaagaggtggaattaattgttcaagagaaaccatttactgttgagatctcccctggacccc ggattgctgctcagattggagactcagtcatgttgacatgtagtgtcatgggctgtgaatccccatctttctcctggaga acccagatagacagccctctgagcgggaaggtgaggagtgaggggaccaattccacgctgaccctgagccctgtgagttt tgagaacgaacactcttatctgtgcacagtgacttgtggacataagaaactggaaaagggaatccaggtggagctctact cattccctagagatccagaaatcgagatgagtggtggcctcgtgaatgggagctctgtcactgtaagctgcaaggttcct agcgtgtacccccttgaccggctggagattgaattacttaagggggagactattctggagaatatagagtttttggagga tacggatatgaaatctctagagaacaaaagtttggaaatgaccttcatccctaccattgaagatactggaaaagctcttg tttgtcaggctaagttacatattgatgacatggaattcgaacccaaacaaaggcagagtacgcaaacactttatgtcaat gttgcccccagagatacaaccgtcttggtcagcccttcctccatcctggaggaaggcagttctgtgaatatgacatgctt gagccagggctttcctgctccgaaaatcctgtggagcaggcagctccctaacggggagctacagcctctttctgagaatg caactctcaccttaatttctacaaaaatggaagattctggggtttatttatgtgaaggaattaaccaggctggaagaagc agaaaggaagtggaattaattatccaagttactccaaaagacataaaacttacagcttttccttctgagagtgtcaaaga aggagacactgtcatcatctcttgtacatgtggaaatgttccagaaacatggataatcctgaagaaaaaagcggagacag gagacacagtactaaaatctatagatggcgcctataccatccgaaaggcccagttgaaggatgcgggagtatatgaatgt gaatctaaaaacaaagttggctcacaattaagaagtttaacacttgatgttcaaggaagagaaaacaacaaagactattt ttctcctgagcttctcgtgctctattttgcatcctccttaataatacctgccattggaatgataatttactttgcaagaa aagccaacatgaaggggtcatatagtcttgtagaagcacagaaatcaaaagtgtag (SEQ ID NO: 12026) gcaggaacagtgctagtattgctcgagcccgagggctggaggttaggggatgaaggtctgcttccacgctttgcactgaa ttagggctagaattggggatgggggtaggggcgcattccttcgggagccgaggcttaagtcctcggggtcctgtactcga tgccgtttctcctatctctgagcctcagaactgtcttcagtttccgtacaagggtaaaaaggcgctctctgccccatccc ccccgacctcgggaacaagggtccgcattgaaccaggtgcgaatgttctctctcattctgcgccgttcccgcctcccctc ccccagccgcggcccccgcctccccccgcactgcaccctcggtgttggctgcagcccgcgagcagttcccgtcaatccct ccccccttacacaggatgtccatattaggacatctgcgtcagcaggtttccacggcctttccctgtagccctggggggag ccatccccgaaacccctcatcttggggggcccacgagacctctgagacaggaactgcgaaatgctcacgagattaggaca cgcgccaaggcgggggcagggagctgcgagcgctggggacgcagccgggcggccgcagaagcgcccaggcccgcgcgcca cccctctggcgccaccgtggttgagcccgtgacgtttacactcattcataaaacgcttgttataaaagcagtggctgcgg cgcctcgtactccaaccgcatctgcagcgagcaactgagaagccaagactgagccggcggccgcggcgcagcgaacgagc agtgaccgtgctcctacccagctctgcttcacagcgcccacctgtctccgcccctcggcccctcgcccggctttgcctaa ccgccacgatgatgttctcgggcttcaacgcagactacgaggcgtcatcctcccgctgcagcagcgcgtccccggccggg gatagcctctcttactaccactcacccgcagactccttctccagcatgggctcgcctgtcaacgcgcaggtaaggctggc ttcccgtcgccgcggggccgggggcttggggtcgcggaggaggagacaccgggcgggacgctccagtagatgagtagggg gc cccttgtgcctggagggaggctgccgtggccggagcggtgccggctcgggggctcgggacttgctctgagcgcacgc acgcttgccatagtaagaattggttcccccttcgggaggcaggttcgttctgagcaacctctggtctgcactccaggacg gatctctgacattagctggagcagacgtgtcccaagcacaaactcgctaactagagcctggcttcttcggggaggtggca gaaagcggcaatcccccctcccccggcagcctggagcacggaggagggatgagggaggagggtgcagcgggcgggtgtgt aaggcagtttcattgataaaaagcgagttcattctggagactccggagcggcgcctgcgtcagcgcagacgtcagggata tttataacaaaccccctttcaagcaagtgatgctgaagggataacgggaacgcagcggcaggatggaagagacaggcact gcgctgcggaatgcctgggaggaaaagggggagacctttcatccaggatgagggacatttaagatgaaatgtccgtggca ggatcgtttctcttcactgctgcatgcggcactgggaactcgccccacctgtgtccggaacctgctcgctcacgtcggct ttccccttctgttttgttctaggacttctgcacggacctggccgtctccagtgccaacttcattcccacggtcactgcca tctcgaccagtccggacctgcagtggctggtgcagcccgccctcgtctcctctgtggccccatcgcagaccagagcccct caccctttcggagtccccgccccctccgctggggcttactccagggctggcgttgtgaagaccatgacaggaggccgagc gcagagcattggcaggaggggcaaggtggaacaggtgaggaactctagcgtactcttcctgggaatgtgggggctgggtg ggaagcagccccggagatgcaggagcccagtacagaggatgaagccactgatggggctggctgcacatccgtaactggga gccctggctccaagcccattccatcccaactcagactctgagtctcaccctaagaagtactctcatagtttcttccctaa gtttcttaccgcatgctttcagactgggctcttctttgttctcttgctgaggatcttattttaaatgcaagtcacaccta ttctgcaactgcaggtcagaaatggtttcacagtggggtgccaggaagcagggaagctgcaggagccagttctactgggg tgggtgaatggaggtgatggcagacacttttactgaatgtcggtctttttttgtgattattctagttatctccagaagaa gaagagaaaaggagaatccgaagggaaaggaataagatggctgcagccaaatgccgcaaccggaggagggagctgactga tacactccaagcggtagg actctgtgggttgctcctttttaaaacttaagggaaagttggagattgagcataagggccc ttgagtaagactgtgtcttatgctttcctttatccctctgtatacaggagacagaccaactagaagatgagaagtctgct ttgcagaccgagattgccaacctgctgaaggagaaggaaaaactagagttcatcctggcagctcaccgacctgcctgcaa gatccctgatgacctgggcttcccagaagagatgtctgtggcttcccttgatctgactgggggcctgccagaggttgcca ccccggagtctgaggaggccttcaccctgcctctcctcaatgaccctgagcccaagccctcagtggaacctgtcaagagc atcagcagcatggagctgaagaccgagccctttgatgacttcctgttcccagcatcatccaggcccagtggctctgagac agcccgctccgtgccagacatggacctatctgggtccttctatgcagcagactgggagcctctgcacagtggctccctgg ggatggggcccatggccacagagctggagcccctgtgcactccggtggtcacctgtactcccagctgcactgcttacacg tcttccttcgtcttcacctaccccgaggctgactccttccccagctgtgcagctgcccaccgcaagggcagcagcagcaa tgagccttcctctgactcgctcagctcacccacgctgctggccctgtgagggggcagggaaggggaggcagccggcaccc acaagtgccactgcccgagctggtgcattacagagaggagaaacacatcttccctagagggttcctgtagacctagggag gaccttatctgtgcgtgaaacacaccaggctgtgggcctcaaggacttgaaagcatccatgtgtggactcaagtccttac ctcttccggagatgtagcaaaacgcatggagtgtgtattgttcccagtgacacttcagagagctggtagttagtagcatg ttgagccaggcctgggtctgtgtctcttttctctttctccttagtcttctcatagcattaactaatctattgggttcatt attggaattaacctggtgctggatattttcaaattgtatctagtgcagctgattttaacaataactactgtgttcctggc aatagtgtgttctgattagaaatgaccaatattatactaagaaaagatacgactttattttctggtagatagaaataaat agctatatccatgtactgtagtttttcttcaacatcaatgttcattgtaatgttactgatcatgcattgttgaggtggtc tgaatgttctgacattaacagttttccatgaaaacgttttattgtgtttttaatttatttattaagatggattctcagat atttatatttttattttatttttttctaccttgaggtcttttgacatgtggaaagtgaatttgaatgaaaaatttaagca ttgtttgcttattgttccaagacattgtcaataaaagcatttaagttgaatgcgaccaaccttgtgctcttttcattctg gaagtcttgtaagtttctgaaaggtattattggagaccagtttgtcaagaagggtagctgctggagggggacacaccctc tgtctgatcccttatcaaagaggacaaggaaactatagagctgattttagaatattttacaaatacatgccttccattgg aatgctaagattttctactgcttctggggacgggaaaccgctgtgtaacagcttttgtgggaatacattttttctgtttc agtactcgcagggggaaatatttaaattttgttgtgctaatattaaattcagatgttttgatcttaaaggaaccctttaa gcaaacagaacctagctttgtacagactattttaactttttattctcacaaaatcacgtggagggttattctacttcaaa gatgagcaaattgaagaatggttagaataaacaactttcttgatattccgttatcggcattagaatcttcctgctcgtta 5 tcgtatccagcaggctgaactgcctcttgatacttggttaaaaaaaattttcaggccgggcgcggtggcccatgcctgta atcctagcactttgggaggccgaggcaggcggatcacctgaggtcgggagttcgagaccagcctgaccaacatggagaaa ccccgtctttactaaaaatacaaaattagcctggtgtggtggtgcatgcctgtaatcctagctacttgagaggctgagac aggaaaatcacttgaactcgggaggcggatgttgcagcgaactgagattgcgccattgcactccagcctgggcaacaaga ttgaaactctgtttaaaaaaaaaagttttcactaatgtgtacatttttttgtactcttttattctcgaaagggaaggagg

10 gctattgccctatcccttattaataaatgcattgtggtttctggtttctctaataccatatgcccttcattcagtttata gtgggcggaagtgggggagaaaaagttgctcagaaatcaaaagatatctcaaacagcacaaataatggctgatcgttctg caaacaaaaagttacataatagctcaagaaggagaagtcaacatgactctgaacaagctttaacttagaaactttatcat cttaaggaagaacgtgacctttgtccaggacgtctctggtaatggggcacttacacacacatgcacacgtacaaaccaca gggaaaggagaccgcccttctgcctctgctcgcgagtatcacgcaggcaccatgcactatgttttcacacacactgggtg

15 gaagaagagcttcagcgccagtcttctaatgctttggtgataatgaaaatcactgggtgcttatggggtgtcatattcaa tcgagttaaaagttttaattcaaaatgacagttttactgaggttgatgttctcgtctatgatatctctgcccctcccata aaaatggacatttaaaagcaacttaccgctctttagatcactcctatatcacacaccacttggggtgctgtttctgctag acttgtgatgacagtggccttaggatccctgtttgctgtitcaaagggcaaatattttatagcctttaaatatacctaaac taaatacagaattaatataactaacaaacacctggtctgaaataacaaggtgatctaccctggaaggaacccagctggtg

20 ggccaggagcggtggctcacacctgtaattccagcactttgggaggctgagacaggaggatcactggagtccaggagttt gagaccagcctgggcaacatggcaaaacccagtgtgcttctgttgtcccagctacactactcaggaggctgaggcaggag tatgacttgagcctgggagggggaggttgcagagaactgatattgcaccaccactgcactccagcctgggtgacacagca aaaccctatctcaaaaaaaaaaaaaaaaaaaaggaacccagctggttcctgtaggtgtgcaataataacaaccagaggaa gaaaaggaagacgatttcccagatgaagaagggcagctggaccttcggac (SEQ ID NO: 12027)

25 gcagccgggcggccgcagaagcgcccaggcccgcgcgccacccctctggcgccaccgtggttgagcccgtgacgtttaca ctcattcataaaacgcttgttataaaagcagtggctgcggcgcctcgtactccaaccgcatctgcagcgagcaactgaga agccaagactgagccggcggccgcggcgcagcgaacgagcagtgaccgtgctcctacccagctctgcttcacagcgccca cctgtctccgcccctcggcccctcgcccggctttgcctaaccgccacgatgatgttctcgggcttcaacgcagactacga ggcgtcatcctcccgctgcagcagcgcgtccccggccggggatagcctctcttactaccactcacccgcagactccttct

30 ccagcatgggctcgcctgtcaacgcgcaggtaaggctggcttcccgtcgccgcggggccgggggcttggggtcgcggagg aggagacaccgggcgggacgctccagtagatgagtagggggctcccttgtgcctggagggaggctgccgtggccggagcg gtgccggctcgggggctcgggacttgctctgagcgcacgcacgcttgccatagtaagaattggttcccccttcgggaggc aggttcgttctgagcaacctctggtctgcactccaggacggatctctgacattagctggagcagacgtgtcccaagcaca aactcgctaactagagcctggcttcttcggggaggtggcagaaagcggcaatcccccctcccccggcagcctggagcacg

35 gaggagggatgagggaggagggtgcagcgggcgggtgtgtaaggcagtttcattgataaaaagcgagttcattctggaga ctccggagcggcgcctgcgtcagcgcagacgtcagggatatttataacaaaccccctttcaagcaagtgatgctgaaggg ataacgggaacgcagcggcaggatggaagagacaggcactgcgctgcggaatgcctgggaggaaaagggggagacctttc atccaggatgagggacatttaagatgaaatgtccgtggcaggatcgtttctcttcactgctgcatgcggcactgggaact cgccccacctgtgtccggaacctgctcgctcacgtcggctttccccttctgttttgttctaggacttctgcacggacctg

40 gccgtctccagtgccaacttcattcccacggtcactgccatctcgaccagtccggacctgcagtggctggtgcagcccgc cctcgtctcctctgtggccccatcgcagaccagagcccctcaccctttcggagtccccgccccctccgctggggcttact ccagggctggcgttgtgaagaccatgacaggaggccgagcgcagagcattggcaggaggggcaaggtggaacaggtgagg aactctagcgtactcttcctgggaatgtgggggctgggtgggaagcagccccggagatgcaggagcccagtacagaggat gaagccactgatggggctggctgcacatccgtaactgggagccctggctccaagcccattccatcccaactcagactctg

45 agtctcaccctaagaagtactctcatagtttcttccctaagtttcttaccgcatgctttcagactgggctcttctttgtt ctcttgctgaggatcttattttaaatgcaagtcacacctattctgcaactgcaggtcagaaatggtttcacagtggggtg ccaggaagcagggaagctgcaggagccagttctactggggtgggtgaatggaggtgatggcagacacttttactgaatgt cggtctttttttgtgattattctagttatctccagaagaagaagagaaaaggagaatccgaagggaaaggaataagatgg ctgcagccaaatgccgcaaccggaggagggagctgactgatacactccaagcggtaggtactctgtgggttgctcctttt

50 taaaacttaagggaaagttggagattgagcataagggcccttgagtaagactgtgtcttatgctttcctttatccctctg tatacaggagacagaccaactagaagatgagaagtctgctttgcagaccgagattgccaacctgctgaaggagaaggaaa aactagagttcatcctggcagctcaccgacctgcctgcaagatccctgatgacctgggcttcccagaagagatgtctgtg gcttcccttgatctgactgggggcctgccagaggttgccaccccggagtctgaggaggccttcaccctgcctctcctcaa tgaccctgagcccaagccctcagtggaacctgtcaagagcatcagcagcatggagctgaagaccgagccctttgatgact

55 tcctgttcccagcatcatccaggcccagtggctctgagacagcccgctccgtgccagacatggacctatctgggtccttc tatgcagcagactgggagcctctgcacagtggctccctggggatggggcccatggccacagagctggagcccctgtgcac tccggtggtcacctgtactcccagctgcactgcttacacgtcttccttcgtcttcacctaccccgaggctgactccttcc ccagctgtgcagctgcccaccgcaagggcagcagcagcaatgagccttcctctgactcgctcagctcacccacgctgctg gccctgtgagggggcagggaaggggaggcagccggcacccacaagtgccactgcccgagctggtgcattacagagaggag

60. aaacacatcttccctagagggttcctgtagacctagggaggaccttatctgtgcgtgaaacacaccaggctgtgggcctc aaggacttgaaagcatccatgtgtggactcaagtccttacctcttccggagatgtagcaaaacgcatggagtgtgtattg ttcccagtgacacttcagagagctggtagttagtagcatgttgagccaggcctgggtctgtgtctcttttctctttctcc ttagtcttctcatagcattaactaatctattgggttcattattggaattaacctggtgctggatattttcaaattgtatc tagtgcagctgattttaacaataactactgtgttcctggcaatagtgtgttctgattagaaatgaccaatattatactaa

65 gaaaagatacgactttattttctggtagatagaaataaatagctatatccatgtactgtagtttttcttcaacatcaatg ttcattgtaatgttactgatcatgcattgttgaggtggtctgaatgttctgacattaacagttttccatgaaaacgtttt attgtgtttttaatttatttattaagatggattctcagatatttatatttttattttatttttttctaccttgaggtctt ttgacatgtggaaagtgaatttgaatgaaaaatttaagcattgtttgcttattgttccaagacattgtcaataaaagcat ttaagttgaatgcgaccaaccttgtgctcttttcattctggaagt (SEQ ID NO: 12028)

70 cctcgaggtcgaagcttatttaaaagcatattttccaatgcctgctttagctgtggaaaaggaagactctccgagggcaa atccaggagtcatggaaaacaatgggcagggcagcttggtgctgtgactggatgggtctttaaggttgtttcccttgaat aaagaatgagggaattccaccaggggaaggagagtagaccaaacatttggtgaacagaaagggagacagagtctttagtg ttattccccaaatattcctggagagncctttgagacacctggtaggattatagtgatctaaagaggcatggccatgtgac tgcttnggccaatgatgtatgggcagaagtgatgtgtgccataagtggatgctctgacagacatgatgttccgagttcct

75 tccccacagncaggatagctgtgaaaaggggtatcaacacgaggcctccttcagcctgagccctttagtgactacaatga gcagagctaccctgccaacctacaacggtcatgtagnagaaatgaccaactttcactggaataagncactgatatgttag ggttgπntggtagggcagcataacactrmctntcctgacagaactgggagtgagagataaggctggagagagaaggagtt ggattgtgaaaanccccttctccaaggcataggaatcggaactctcctgattgtaaggaaaagccaatgaaggcttccaa gcaggggcgttaacatgaacagatttgttatttttttggatgaaatatgctatttctcaacataaggagaagatcagcct

80 actaaaccacatgaggcagagaggaacacacagaaccttagccaaaagatatatatttatgcaaagtcctaagtcttgaa atttctaaatacaggagctctgaacggagttacagtcagaggatcaggcaagaaaatttcttctatgccacaagcgctat ttcctctgcagataactaatactccacaagaaagtttgccagagtagagaaaatacaaaggaatgtaacacagacctgag gtcaatttccagctgcctgtgtgacctcaacaaagatacttaacctctctgggcctatttcctcacatgttaaatctgga taataatatatgtctctcaagacagttgtggggagaaaacagcgtatttaaattgcttaggagaatgcctggcagataat aagtgtttaatacatgaaactgatttttattactgttattaaaaaatatttagaacaccaactccctgaatacaacagaa aatgattcagggcaacagacagaggagaatgttctctccttgaggaagcaactggatcttgtcatcactgtatacctacc taccccaccccctccccagctcagtgcctggctcacagtaggctttcagttaccctctgcagatcagtgaaagctaggtg agtgcccggagtgaagaaaagttggcaggtttcccactgataccagctgctgttggtttctgaacactcaaagccgcaaa taccttagggctgggggcaatgaacccaaggctgaattccaagttcagaagcagcgaagtctgaatttagaacctaggac ttaaactgctgcaggtccaacttcaagccccagttttagacagaggcttgggaaagatctgacttctaacccggttcccc ctcccctcctcccctcgatgcttctcacaggaaagtacacctggtcctgccaaatcgcactcttatatcctggcatccta tccaggctctgcgaggatggaaactgcgaggcaggggagggaagcgggctgtttggccaccacctccctagtgctgcagg cgaccctgtcacactaaactcctggcagcccagtgaggtggacggcaccgccccacctgcagatgagggaaatgaagctc ggaggagttccgtgatttgcttgcttcacactgtggtagcctggccacgaaagaaccaaggattccgacttcggattctt ccaccacacactttcgtcctaagggtgggggcggggggagaataaaataaccgcggaaaaggaaccacttacatgtgtct agcgcttcctagaggctacccaggatatgcgcccaccacccggccggagtgcagagatttgaagtccaggttctaccccg ggctccgagtactactgcgtgactttatgcgagtgtcgccgccttctgggcttgttttcccggaagcaactcggcgcgga tggagtgtgtgtgtgcgcgcgcgcgttatgttgtgcgtgttgtgttagcgtgtgcgtgttgtccgagtttcggatcgcct acacctgtgaacccccgcgccctttcccccacggtcccggagatgaagtggggtgcaacggagactcagctgagcgtcca gtttcgggcaatacaaatctctcggcttctacgagcagccacacgaccccgcggaccgtcgctcctgaacttgaccgaga tgcaaacttcggagtgttctcaacgtgggggccgactctcggagaccgccctaaacttaagtccccttaggctcgcccca cctggacttcacatagccaccttaagggcggtattcccgcccccggaagtgcgggtggcagcgtacttggattctcagcc tccagccccgcgcggtggcggccgcggtggatgacttcgggccccacaagtggaaacaacaaccacccctcgcccgcacc cctggcccaaaacaactggccaggttccctcgtcccgggtccctgcatcccccgcatccccgtccgcagccgtgaacttg agcccccctccatcagaggttgcgagcgtcgccgctcggcagccaccgtcactagacagtcaaaccccaagacgtcagcc cacaatgcaccgggcgggccgggaaaaacggcccggggaggggaccggggaacagagggccgagaggcgtgcggcagggg ggagggtaggagaaagaagggcccgactgtaggagggcagcggagcattacctcatcccgtgagcctccgcgggcccaga gaagaatcttctagggtggagtctccatggtgacgggcgggcccgcccccctgagagcgacgcgagccaatgggaaggcc ttggggtgacatcatgggctatttttaggggttgactggtagcagataagtgttgagctcgggctggataagggctca (SEQ ID NO : 12029) cccggggaggggaccggggaacagagggccgagaggcgtgcggcaggggggagggtaggagaaagaagggcccgactgta ggagggcagcggagcattacctcatcccgtgagcctccgcgggcccagagaagaatcttctagggtggagtctccatggt gacgggcgggcccgcccccctgagagcgacgcgagccaatgggaaggccttggggtgacatcatgggctatttttagggg ttgactggtagcagataagtgttgagctcgggctggataagggctcagagttgcactgagtgtggctgaagcagcgaggc gggagtggaggtgcgcggagtcaggcagacagacagacacagccagccagccaggtcggcagtatagtccgaactgcaaa tcttattttcttttcaccttctctctaactgcccagagctagcgcctgtggctcccgggctggtggttcgggagtgtcca gagagccttgtctccagccggccccgggaggagagccctgctgcccaggcgctgttgacagcggcggaaagcagcggtac cccacgcgcccgccgggggacgtcggcgagcggctgcagcagcaaagaactttcccggcggggaggaccggagacaagtg gcagagtcccggagcgaacttttgcaagcctttcctgcgtcttaggcttctccacggcggtaaagaccagaaggcggcgg agagccacgcaagagaagaaggacgtgcgctcagcttcgctcgcaccggttgttgaacttgggcgagcgcgagccgcggc tgccgggcgccccctccccctagcagcggaggaggggacaagtcgtcggagtccgggcggccaagacccgccgccggccg gccactgcagggtccgcactgatccgctccgcggggagagccgctgctctgggaagtgagttcgcctgcggactccgagg aaccgctgcgcccgaagagcgctcagtgagtgaccgcgacttttcaaagccgggtagcgcgcgcgagtcgacaagtaaga gtgcgggaggcatcttaattaaccctgcgctccctggagcgagctggtgaggagggcgcagcggggacgacagccagcgg gtgcgtgcgctcttagagaaactttccctgtcaaaggctccggggggcgcgggtgtcccccgcttgccagagccctgttg cggccccgaaacttgtgcgcgcacgccaaactaacctcacgtgaagtgacggactgttctatgactgcaaagatggaaac gaccttctatgacgatgccctcaacgcctcgttcctcccgtccgagagcggaccttatggctacagtaaccccaagatcc tgaaacagagcatgaccctgaacctggccgacccagtggggagcctgaagccgcacctccgcgccaagaactcggacctc ctcacctcgcccgacgtggggctgctcaagctggcgtcgcccgagctggagcgcctgataatccagtccagcaacgggca catcaccaccacgccgacccccacccagttcctgtgccccaagaacgtgacagatgagcaggaggggttcgccgagggσt tcgtgcgcgccctggccgaactgcacagccagaacacgctgcccagcgtcacgtcggcggcgcagccggtcaacggggca ggcatggtggctcccgcggtagcctcggtggcagggggcagcggcagcggcggcttcagcgccagcctgcacagcgagcc gccggtctacgcaaacctcagcaacttcaacccaggcgcgctgagcagcggcggcggggcgccctcctacggcgcggccg gcctggcctttcccgcgcaaccccagcagcagcagcagccgccgcaccacctgccccagcagatgcccgtgcagcacccg cggctgcaggccctgaaggaggagcctcagacagtgcccgagatgcccggcgagacaccgcccctgtcccccatcgacat ggagtcccaggagcggatcaaggcggagaggaagcgcatgaggaaccgcatcgctgcctccaagtgccgaaaaaggaagc tggagagaatcgcccggctggaggaaaaagtgaaaaccttgaaagctcagaactcggagctggcgtccacggccaacatg ctcagggaacaggtggcacagcttaaacagaaagtcatgaaccacgttaacagtgggtgccaactcatgctaacgcagca gttgcaaacattttgaagagagaccgtcgggggctgaggggcaacgaagaaaaaaaataacacagagagacagacttgag aacttgacaagttgcgacggagagaaaaaagaagtgtccgagaactaaagccaagggtatccaagttggactgggttcgg tctgacggcgcccccagtgtgcacgagtgggaaggacttggtcgcgccctcccttggcgtggagccagggagcggccgcc tgcgggctgccccgctttgcggacgggctgtccccgcgcgaacggaacgttggactttcgttaacattgaccaagaactg catggacctaacattcgatctcattcagtattaaaggggggagggggagggggttacaaactgcaatagagactgtagat tgcttctgtagtactccttaagaacacaaagcggggggagggttggggaggggcggcaggagggaggtttgtgagagcga ggctgagcctacagatgaactctttctggcctgctttcgttaactgtgtatgtacatatatatattttttaatttgatta aagctgattactgtcaataaacagcttcatgcctttgtaagttatttcttgtttgtttgtttgggtatcctgcccagtgt tgtttgtaaataagagatttggagcactctgagtttaccatttgtaataaagtatataatttttttatgttttgtttctg aaaattccagaaaggatatttaagaaaatacaataaactattggaaagtactcccctaacctcttttctgcatcatctgt agatcctagtctatctaggtggagttgaaagagttaagaatgctcgataaaatcactctcagtgcttcttactattaagc agtaaaaactgttctctattagacttagaaataaatgtacctgatgtacctgatgctatgtcaggcttcatactccacgc tcccccagcgtatctatatggaattgcttaccaaaggctagtgcgatgtttcaggaggctggaggaaggggggttgcagt ggagagggacagcccactgagaagtcaaacatttcaaagtttggattgcatcaagtggcatgtgctgtgaccatttataa tgttagaaattttacaataggtgcttattctcaaagcaggaattggtggcagattttacaaaagatgtatccttccaatt tggaatcttctctttgacaattcctagataaaaagatggcctttgtcttatgaatat ataacagcattctgtcacaat aaatgtattcaaataccaataacagatcttgaattgcttccctttactacttttttgttcccaagttatatactgaagtt tttatttttagttgctgaggtt (SEQ ID NO: 12030) gcaggaacagtgctagtattgctcgagcccgagggctggaggttaggggatgaaggtctgcttccacgctttgcactgaa ttagggctagaattggggatgggggtaggggcgcattccttcgggagccgaggcttaagtcctcggggtcctgtactcga tgccgtttctcctatctctgagcctcagaactgtcttcagtttccgtacaagggtaaaaaggcgctctctgccccatccc ccccgacctcgggaacaagggtccgcattgaaccaggtgcgaatgttctctctcattctgcgccgttcccgcctcccctc ccccagccgcggcccccgcctccccccgcactgcaccctcggtgttggctgcagcccgcgagcagttcccgtcaatccct ccccccttacacaggatgtccatattaggacatctgcgtcagcaggtttccacggcctttccctgtagccctggggggag ccatccccgaaacccctcatcttggggggcccacgagacctctgagacaggaactgcgaaatgctcacgagattaggaca cgcgccaaggcgggggcagggagctgcgagcgctggggacgcagccgggcggccgcagaagcgcccaggcccgcgcgcca cccctctggcgccaccgtggttgagcccgtgacgtttacactcattcataaaacgcttgttataaaagcagtggctgcgg cgcctcgtactccaaccgcatctgcagcgagcaactgagaagccaagactgagccggcggccgcggcgcagcgaacgagc agtgaccgtgctcctacccagctctgcttcacagcgcccacctgtctccgcccctcggcccctcgcccggctttgcctaa ccgccacgatgatgttctcgggcttcaacgcagactacgaggcgtcatcctcccgctgcagcagcgcgtccccggccggg gatagcctctcttactaccactcacccgcagactccttctccagcatgggctcgcctgtcaacgcgcaggtaaggctggc ttcccgtcgccgcggggccgggggcttggggtcgcggaggaggagacaccgggcgggacgctccagtagatgagtagggg gctcccttgtgcctggagggaggctgccgtggccggagcggtgccggctcgggggctcgggacttgctctgagcgcacgc acgcttgccatagtaagaattggttcccccttcgggaggcaggttcgttctgagcaacctctggtctgcactccaggacg gatctctgacattagctggagcagacgtgtcccaagcacaaactcgctaactagagcctggcttcttcggggaggtggca gaaagcggcaatcccccctcccccggcagcctggagcacggaggagggatgagggaggagggtgcagcgggcgggtgtgt aaggcagtttcattgataaaaagcgagttcattctggagactccggagcggcgcctgcgtcagcgcagacgtcagggata tttataacaaaccccctttcaagcaagtgatgctgaagggataacgggaacgcagcggcaggatggaagagacaggcact gcgctgcggaatgcctgggaggaaaagggggagacctttcatccaggatgagggacatttaagatgaaatgtccgtggca ggatcgtttctcttcactgctgcatgcggcactgggaactcgccccacctgtgtccggaacctgctcgctcacgtcggct ttccccttctgttttgttctaggacttctgcacggacctggccgtctccagtgccaacttcattcccacggtcactgcca tctcgaccagtccggacctgcagtggctggtgcagcccgccctcgtctcctctgtggccccatcgcagaccagagcccct caccctttcggagtccccgccccctccgctggggcttactccagggctggcgttgtgaagaccatgacaggaggccgagc gcagagcattggcaggaggggcaaggtggaacaggtgaggaactctagcgtactcttcctgggaatgtgggggctgggtg ggaagcagccccggagatgcaggagcccagtacagaggatgaagccactgatggggctggctgcacatccgtaactggga gccctggctccaagcccattccatcccaactcagactctgagtctcaccctaagaagtactctcatagtttcttccctaa gtttcttaccgcatgctttcagactgggctcttctttgttctcttgctgaggatcttattttaaatgcaagtcacaccta ttctgcaactgcaggtcagaaatggtttcacagtggggtgccaggaagcagggaagctgcaggagccagttctactgggg tgggtgaatggaggtgatggcagacacttttactgaatgtcggtctttttttgtgattattctagttatctccagaagaa gaagagaaaaggagaatccgaagggaaaggaataagatggctgcagccaaatgccgcaaccggaggagggagctgactga tacactccaagcggtaggtactctgtgggttgctcctttttaaaacttaagggaaagttggagattgagcataagggccc ttgagtaagactgtgtcttatgctttcctttatccctctgtatacaggagacagaccaactagaagatgagaagtctgct ttgcagaccgagattgccaacctgctgaaggagaaggaaaaactagagttcatcctggcagctcaccgacctgcctgcaa gatccctgatgacctgggcttcccagaagagatgtctgtggcttcccttgatctgactgggggcctgccagaggttgcca ccccggagtctgaggaggccttcaccctgcctctcctcaatgaccctgagcccaagccctcagtggaacctgtcaagagc atcagcagcatggagctgaagaccgagccctttgatgacttcctgttcccagcatcatccaggcccagtggctctgagac agcccgctccgtgccagacatggacctatctgggtccttctatgcagcagactgggagcctctgcacagtggctccctgg ggatggggcccatggccacagagctggagcccctgtgcactccggtggtcacctgtactcccagctgcactgcttacacg tcttccttcgtcttcacctaccccgaggctgactccttccccagctgtgcagctgcccaccgcaagggcagcagcagcaa tgagccttcctctgactcgctcagctcacccacgctgctggccctgtgagggggcagggaaggggaggcagccggcaccc acaagtgccactgcccgagctggtgcattacagagaggagaaacacatcttccctagagggttcctgtagacctagggag gaccttatctgtgcgtgaaacacaccaggctgtgggcctcaaggacttgaaagcatccatgtgtggactcaagtccttac ctcttccggagatgtagcaaaacgcatggagtgtgtattgttcccagtgacacttcagagagctggtagttagtagcatg ttgagccaggcctgggtctgtgtctcttttctctttctccttagtcttctcatagcattaactaatctattgggttcatt attggaattaacctggtgctggatattttcaaattgtatctagtgcagctgattttaacaataactactgtgttcctggc aatagtgtgttctgattagaaatgaccaatattatactaagaaaagatacgactttattttctggtagatagaaataaat agctatatccatgtactgtagtttttcttcaacatcaatgttcattgtaatgttactgatcatgcattgttgaggtggtc tgaatgttctgacattaacagttttccatgaaaacgttttattgtgtttttaatttatttattaagatggattctcagat atttatatttttattttatttttttctaccttgaggtcttttgacatgtggaaagtgaatttgaatgaaaaatttaagca ttgtttgcttattgttccaagacattgtcaataaaagcatttaagttgaatgcgaccaaccttgtgctcttttcattctg gaagtcttgtaagtttctgaaaggtattattggagaccagtttgtcaagaagggtagctgctggagggggacacaccctc tgtctgatcccttatcaaagaggacaaggaaactatagagctgattttagaatattttacaaatacatgccttccattgg aatgctaagattttctactgcttctggggacgggaaaccgctgtgtaacagcttttgtgggaatacattttttctgtttc agtactcgcagggggaaatatttaaattttgttgtgctaatattaaattcagatgttttgatcttaaaggaaccctttaa gcaaacagaacctagctttgtacagactattttaactttttattctcacaaaatcacgtggagggttattctacttcaaa gatgagcaaattgaagaatggttagaataaacaactttcttgatattccgttatcggcattagaatcttcctgctcgtta tcgtatccagcaggctgaactgcctcttgatacttggttaaaaaaaattttcaggccgggcgcggtggcccatgcctgta atcctagcactttgggaggccgaggcaggcggatcacctgaggtcgggagttcgagaccagcctgaccaacatggagaaa ccccgtctttactaaaaatacaaaattagcctggtgtggtggtgcatgcctgtaatcctagctacttgagaggctgagac aggaaaatcacttgaactcgggaggcggatgttgcagcgaactgagattgcgccattgcactccagcctgggcaacaaga ttgaaactctgtttaaaaaaaaaagttttcactaatgtgtacatttttttgtactcttttattctcgaaagggaaggagg gctattgccctatcccttattaataaatgcattgtggtttctggtttctctaataccatatgccct cattcagtttata gtgggcggaagtgggggagaaaaagttgctcagaaatcaaaagatatctcaaacagcacaaataatggctgatcgttctg caaacaaaaagttacataatagctcaagaaggagaagtcaacatgactctgaacaagctttaacttagaaactttatcat cttaaggaagaacgtgacctttgtccaggacgtctctggtaatggggcacttacacacacatgcacacgtacaaaccaca gggaaaggagaccgcccttctgcctctgctcgcgagtatcacgcaggcaccatgcactatgttttcacacacactgggtg gaagaagagcttcagcgccagtcttctaatgctttggtgataatgaaaatcactgggtgcttatggggtgtcatattcaa tcgagttaaaagttttaattcaaaatgacagttttactgaggttgatgttctcgtctatgatatctctgcccctcccata aaaatggacatttaaaagcaacttaccgctctttagatcactcctatatcacacaccacttggggtgctgtttctgctag acttgtgatgacagtggccttaggatccctgtttgctgttcaaagggcaaatattttatagcctttaaatatacctaaac taaatacagaattaatataactaacaaacacctggtctgaaataacaaggtgatctaccctggaaggaacccagctggtg ggccaggagcggtggctcacacctgtaattccagcactttgggaggctgagacaggaggatcactggagtccaggagttt gagaccagcctgggcaacatggcaaaacccagtgtgcttctgttgtcccagctacactactcaggaggctgaggcaggag tatgacttgagcctgggagggggaggttgcagagaactgatattgcaccaccactgcactccagcctgggtgacacagca aaaccctatctcaaaaaaaaaaaaaaaaaaaaggaacccagctggttcctgtaggtgtgcaataataac accagaggaa gaaaaggaagacgatttcccagatgaagaagggcagctggaccttcggacgcagccgggcggccgcagaagcgcccaggc ccgcgcgccacccctctggcgccaccgtggttgagcccgtgacgtttacactcattcataaaacgcttgttataaaagca gtggctgcggcgcctcgtactccaaccgcatctgcagcgagcaactgagaagccaagactgagccggcggccgcggcgca gcgaacgagcagtgaccgtgctcctacccagctctgcttcacagcgcccacctgtctccgcccctcggcccctcgcccgg ctttgcctaaccgccacgatgatgttctcgggcttcaacgcagactacgaggcgtcatcctcccgctgcagcagcgcgtc cccggccggggatagcctctcttactaccactcacccgcagactccttctccagcatgggctcgcctgtcaacgcgcagg taaggctggcttcccgtcgccgcggggccgggggcttggggtcgcggaggaggagacaccgggcgggacgctccagtaga tgagtagggggctcccttgtgcctggagggaggctgccgtggccggagcggtgccggctcgggggctcgggacttgctct gagcgcacgc.acgcttgccatagtaagaattggttcccccttcgggaggcaggttcgttctgagcaacctctggtctgca ctccaggacggatctctgacattagctggagcagacgtgtcccaagcacaaactcgctaactagagcctggcttcttcgg ggaggtggcagaaagcggcaatcccccctcccccggcagcctggagcacggaggagggatgagggaggagggtgcagcgg gcgggtgtgtaaggcagtttcattgataaaaagcgagttcattctggagactccggagcggcgcctgcgtcagcgcagac gtcagggatatttataacaaaccccctttcaagcaagtgatgctgaagggataacgggaacgcagcggcaggatggaaga gacaggcactgcgctgcggaatgcctgggaggaaaagggggagacctttcatccaggatgagggacatttaagatgaaat gtccgtggcaggatcgtttctcttcactgctgcatgcggcactgggaactcgccccacctgtgtccggaacctgctcgct cacgtcggctttccccttctgttttgttctaggacttctgcacggacctggccgtctccagtgccaacttcattcccacg gtcactgccatctcgaccagtccggacctgcagtggctggtgcagcccgccctcgtctcctctgtggccccatcgcagac cagagcccctcaccctttcggagtccccgccccctccgctggggcttactccagggctggcgttgtgaagaccatgacag gaggccgagcgcagagcattggcaggaggggcaaggtggaacaggtgaggaactctagcgtactcttcctgggaatgtgg gggctgggtgggaagcagccccggagatgcaggagcccagtacagaggatgaagccactgatggggctggctgcacatcc gtaactgggagccctggctccaagcccattccatcccaactcagactctgagtctcaccctaagaagtactctcatagtt tcttccctaagtttcttaccgcatgctttcagactgggctcttctttgttctcttgctgaggatcttattttaaatgcaa gtcacacctattctgcaactgcaggtcagaaatggtttcacagtggggtgccaggaagcagggaagctgcaggagccagt tctactggggtgggtgaatggaggtgatggcagacacttttactgaatgtcggtctttttttgtgattattctagttatc tccagaagaagaagagaaaaggagaatccgaagggaaaggaataagatggctgcagccaaatgccgcaaccggaggaggg agctgactgatacactccaagcggtaggtactctgtgggttgctcctttttaaaacttaagggaaagttggagattgagc ataagggcccttgagtaagactgtgtcttatgctttcctttatccctctgtatacaggagacagaccaactagaagatga gaagtctgctttgcagaccgagattgccaacctgctgaaggagaaggaaaaactagagttcatcctggcagctcaccgac ctgcctgcaagatccctgatgacctgggcttcccagaagagatgtctgtggcttcccttgatctgactgggggcctgcca gaggttgccaccccggagtctgaggaggccttcaccctgcctctcctcaatgaccctgagcccaagccctcagtggaacc tgtcaagagcatcagcagcatggagctgaagaccgagccctttgatgacttcctgttcccagcatcatccaggcccagtg gctctgagacagcccgctccgtgccagacatggacctatctgggtccttctatgcagcagactgggagcctctgcacagt ggctccctggggatggggcccatggccacagagctggagcccctgtgcactccggtggtcacctgtactcccagctgcac tgcttacacgtcttccttcgtcttcacctaccccgaggctgactccttccccagctgtgcagctgcccaccgcaagggca gcagcagcaatgagccttcctctgactcgctcagctcacccacgctgctggccctgtgagggggcagggaaggggaggca gccggcacccacaagtgccactgcccgagctggtgcattacagagaggagaaacacatcttccctagagggttcctgtag acctagggaggaccttatctgtgcgtgaaacacaccaggctgtgggcctcaaggacttgaaagcatccatgtgtggactc aagtccttacctcttccggagatgtagcaaaacgcatggagtgtgtattgttcccagtgacacttcagagagctggtagt tagtagcatgttgagccaggcctgggtctgtgtctcttttctctttctccttagtcttctcatagcattaactaatctat tgggttcattattggaattaacctggtgctggatattttcaaattgtatctagtgcagctgattttaacaataactactg tgttcctggcaatagtgtgttctgattagaaatgaccaatattatactaagaaaagatacgactttattttctggtagat agaaataaatagctatatccatgtactgtagtttttcttcaacatcaatgttcattgtaatgttactgatcatgcattgt tgaggtggtctgaatgttctgacattaacagttttccatgaaaacgttttattgtgtttttaatttatttattaagatgg attctcagatatttatatttttattttatttttttctaccttgaggtcttttgacatgtggaaagtgaatttgaatgaaa aatttaagcattgtttgcttattgttccaagacattgtcaataaaagcatttaagttgaatgcgaccaaccttgtgctct tttcattctggaagtcctcgaggtcgaagcttatttaaaagcatattttccaatgcctgctttagctgtggaaaaggaag actctccgagggcaaatccaggagtcatggaaaacaatgggcagggcagcttggtgctgtgactggatgggtctttaagg ttgtttcccttgaataaagaatgagggaattccaccaggggaaggagagtagaccaaacatttggtgaacagaaagggag acagagtctttagtgttattccccaaatattcctggagagncctttgagacacctggtaggattatagtgatctaaagag gcatggccatgtgactgcttnggccaatgatgtatgggcagaagtgatgtgtgccataagtggatgctctgacagacatg atgttccgagttccttccccacagncaggatagctgtgaaaaggggtatcaacacgaggcctccttcagcctgagccctt tagtgactacaatgagcagagctaccctgccaacctacaacggtcatgtagnagaaatgaccaactttcactggaataag ncactgatatgttagggttgnntggtagggcagcataacactnnctntcctgacagaactgggagtgagagataaggctg gagagagaaggagttggattgtgaaaanccccttctccaaggcataggaatcggaactctcctgattgtaaggaaaagcc aatgaaggcttccaagcaggggcgttaacatgaacagatttgttatttttttggatgaaatatgctatttctcaacataa ggagaagatcagcctactaaaccacatgaggcagagaggaacacacagaaccttagccaaaagatatatatttatgcaaa gtcctaagtcttgaaatttctaaatacaggagctctgaacggagttacagtcagaggatcaggcaagaaaatttcttcta tgccacaagcgctatttcctctgcagataactaatactccacaagaaagtttgccagagtagagaaaatacaaaggaatg taacacagacctgaggtcaatttccagctgcctgtgtgacctcaacaaagatacttaacctctctgggcctatttcctca catgttaaatctggataataatatatgtctctcaagacagttgtggggagaaaacagcgtatttaaattgcttaggagaa tgcctggcagataataagtgtttaatacatgaaactgatttttattactgttattaaaaaatatttagaacaccaactcc ctgaatacaacagaaaatgattcagggcaacagacagaggagaatgttctctccttgaggaagcaactggatcttgtcat cactgtatacctacctaccccaccccctccccagctcagtgcctggctcacagtaggctttcagttaccctctgcagatc agtgaaagctaggtgagtgcccggagtgaagaaaagttggcaggtttcccactgataccagctgctgttggtttctgaac actcaaagccgcaaataccttagggctgggggcaatgaacccaaggctgaattccaagttcagaagcagcgaagtctgaa tttagaacctaggacttaaactgctgcaggtccaacttcaagccccagttttagacagaggcttgggaaagatctgactt ctaacccggttccccctcccctcctcccctcgatgcttctcacaggaaagtacacctggtcctgccaaatcgcactctta tatcctggcatcctatccaggctctgcgaggatggaaactgcgaggcaggggagggaagcgggctgtttggccaccacct ccctagtgctgcaggcgaccctgtcacactaaactcctggcagcccagtgaggtggacggcaccgccccacctgcagatg agggaaatgaagctcggaggagttccgtgatttgcttgcttcacactgtggtagcctggccacgaaagaaccaaggattc cgacttcggattcttccaccacacactttcgtcctaagggtgggggcggggggagaataaaataaccgcggaaaaggaac cacttacatgtgtctagcgcttcctagaggctacccaggatatgcgcccaccacccggccggagtgcagagatttgaagt ccaggttctaccccgggctccgagtactactgcgtgactttatgcgagtgtcgccgccttctgggcttgttttcccggaa gcaactcggcgcggatggagtgtgtgtgtgcgcgcgcgcgttatgttgtgcgtgttgtgttagcgtgtgcgtgttgtccg agtttcggatcgcctacacctgtgaacccccgcgccctttcccccacggtcccggagatgaagtggggtgcaacggagac tcagctgagcgtccagtttcgggcaatacaaatctctcggcttctacgagcagccacacgaccccgcggaccgtcgctcc tgaacttgaccgagatgcaaacttcggagtgttctcaacgtgggggccgactctcggagaccgccctaaacttaagtccc cttaggctcgccccacctggacttcacatagccaccttaagggcggtattcccgcccccggaagtgcgggtggcagcgta cttggattctcagcctccagccccgcgcggtggcggccgcggtggatgacttcgggccccacaagtggaaacaacaacca cccctcgcccgcacccctggcccaaaacaactggccaggttccctcgtcccgggtccctgcatcccccgcatccccgtcc gcagccgtgaacttgagcccccctccatcagaggttgcgagcgtcgccgctcggcagccaccgtcactagacagtcaaac cccaagacgtcagcccacaatgcaccgggcgggccgggaaaaacggcccggggaggggaccggggaacagagggccgaga ggcgtgcggcaggggggagggtaggagaaagaagggcccgactgtaggagggcagcggagcattacctcatcccgtgagc ctccgcgggcccagagaagaatcttctagggtggagtctccatggtgacgggcgggcccgcccccctgagagcgacgcga gccaatgggaaggccttggggtgacatcatgggctatttttaggggttgactggtagcagataagtgttgagctcgggct ggataagggctcacccggggaggggaccggggaacagagggccgagaggcgtgcggcaggggggagggtaggagaaagaa gggcccgactgtaggagggcagcggagcattacctcatcccgtgagcctccgcgggcccagagaagaatcttctagggtg gagtctccatggtgacgggcgggcccgcccccctgagagcgacgcgagccaatgggaaggccttggggtgacatcatggg ctatttttaggggttgactggtagcagataagtgttgagctcgggctggataagggctcagagttgcactgagtgtggct gaagcagcgaggcgggagtggaggtgcgcggagtcaggcagacagacagacacagccagccagccaggtcggcagtatag tccgaactgcaaatcttattttcttttcaccttctctctaactgcccagagctagcgcctgtggctcccgggctggtggt tcgggagtgtccagagagccttgtctccagccggccccgggaggagagccctgctgcccaggcgctgttgacagcggcgg aaagcagcggtaccccacgcgcccgccgggggacgtcggcgagcggctgcagcagcaaagaactttcccggcggggagga ccggagacaagtggcagagtcccggagcgaacttttgcaagcctttcctgcgtcttaggcttctccacggcggtaaagac cagaaggcggcggagagccacgcaagagaagaaggacgtgcgctcagcttcgctcgcaccggttgttgaacttgggcgag cgcgagccgcggctgccgggcgccccctccccctagcagcggaggaggggacaagtcgtcggagtccgggcggccaagac ccgccgccggccggccactgcagggtccgcactgatccgctccgcggggagagccgctgctctgggaagtgagttcgcct gcggactccgaggaaccgctgcgcccgaagagcgctcagtgagtgaccgcgacttttcaaagccgggtagcgcgcgcgag tcgacaagtaagagtgcgggaggcatcttaattaaccctgcgctccctggagcgagctggtgaggagggcgcagcgggga cgacagccagcgggtgcgtgcgctcttagagaaactttccctgtcaaaggctccggggggcgcgggtgtcccccgcttgc cagagccctgttgcggccccgaaacttgtgcgcgcacgccaaactaacctcacgtgaagtgacggactgttctatgactg caaagatggaaacgaccttctatgacgatgccctcaacgcctcgttcctcccgtccgagagcggaccttatggctacagt aaccccaagatcctgaaacagagcatgaccctgaacctggccgacccagtggggagcctgaagccgcacctccgcgccaa gaactcggacctcctcacctcgcccgacgtggggctgctcaagctggcgtcgcccgagctggagcgcctgataatccagt ccagcaacgggcacatcaccaccacgccgacccccacccagttcctgtgccccaagaacgtgacagatgagcaggagggg ttcgccgagggcttcgtgcgcgccctggccgaactgcacagccagaacacgctgcccagcgtcacgtcggcggcgcagcc ggtcaacggggcaggcatggtggctcccgcggtagcctcggtggcagggggcagcggcagcggcggcttcagcgccagcc tgcacagcgagccgccggtctacgcaaacctcagcaacttcaacccaggcgcgctgagcagcggcggcggggcgccctcc tacggcgcggccggcctggcctttcccgcgcaaccccagcagcagcagcagccgccgcaccacctgccccagcagatgcc cgtgcagcacccgcggctgcaggccctgaaggaggagcctcagacagtgcccgagatgcccggcgagacaccgcccctgt cccccatcgacatggagtcccaggagcggatcaaggcggagaggaagcgcatgaggaaccgcatcgctgcctccaagtgc cgaaaaaggaagctggagagaatcgcccggctggaggaaaaagtgaaaaccttgaaagctcagaactcggagctggcgtc cacggccaacatgctcagggaacaggtggcacagcttaaacagaaagtcatgaaccacgttaacagtgggtgccaactca tgctaacgcagcagttgcaaacattttgaagagagaccgtcgggggctgaggggcaacgaagaaaaaaaataacacagag agacagacttgagaacttgacaagttgcgacggagagaaaaaagaagtgtccgagaactaaagccaagggtatccaagtt ggactgggttcggtctgacggcgcccccagtgtgcacgagtgggaaggacttggtcgcgccctcccttggcgtggagcca gggagcggccgcctgcgggctgccccgctttgcggacgggctgtccccgcgcgaacggaacgttggactttcgttaacat tgaccaagaactgcatggacctaacattcgatctcattcagtattaaaggggggagggggagggggttacaaactgcaat agagactgtagattgcttctgtagtactccttaagaacacaaagcggggggagggttggggaggggcggcaggagggagg tttgtgagagcgaggctgagcctacagatgaactctttctggcctgctttcgttaactgtgtatgtacatatatatattt tttaatttgattaaagctgattactgtcaataaacagcttcatgcctttgtaagttatttcttgtttgtttgtttgggta tcctgcccagtgttgtttgtaaataagagatttggagcactctgagtttaccatttgtaataaagtatataattttttta tgttttgtttctgaaaattccagaaaggatatttaagaaaatacaataaactattggaaagtactcccctaacctctttt ctgcatcatctgtagatcctagtctatctaggtggagttgaaagagttaagaatgctcgataaaatcactctcagtgctt cttactattaagcagtaaaaactgttctctattagacttagaaataaatgtacctgatgtacctgatgctatgtcaggct tcatactccacgctcccccagcgtatctatatggaattgcttaccaaaggctagtgcgatgtttcaggaggctggaggaa ggggggttgcagtggagagggacagcccactgagaagtcaaacatttcaaagtttggattgcatcaagtggcatgtgctg tgaccatttataatgttagaaattttacaataggtgcttattctcaaagcaggaattggtggcagattttacaaaagatg tatccttccaatttggaatcttctctttgacaattcctagataaaaagatggcctttgtcttatgaatatttataacagc attctgtcacaataaatgtattcaaataccaataacagatcttgaattgcttccctttactacttttttgttcccaagtt atatactgaagtttttatttttagttgctgaggtt (SEQ ID NO:12031) cggccccagaaaacccgagcgagtagggggcggcgcgcaggagggaggagaactgggggcgcgggaggctggtgggtgtc gggggtggagatgtagaagatgtgacgccgcggcccggcgggtgccagattagcggacggctgcccgcggttgcaacggg atcccgggcgctgcagcttgggaggcggctctccccaggcggcgtccgcggagacacccatccgtgaaccccaggtcccg ggccgccggctcgccgcgcaccaggggccggcggacagaagagcggccgagcggctcgaggctgggggaccgcgggcgcg gccgcgcgctgccgggcgggaggctggggggccggggccggggccgtgccccggagcgggtcggaggccggggccggggc cgggggacggcggctccccgcgcggctccagcggctcggggatcccggccgggccccgcagggaccatggcagccgggag catcaccacgctgcccgccttgcccgaggatggcggcagcggcgccttcccgcccggccacttcaaggaccccaagcggc tgtactgcaaaaacgggggcttcttcctgcgcatccaccccgacggccgagttgacggggtccgggagaagagcgaccct cacatcaagctacaacttcaagcagaagagagaggagttgtgtctatcaaaggagtgtgtgctaaccgttacctggctat gaaggaagatggaagattactggcttctaaatgtgttacggatgagtgtttcttttttgaacgattggaatctaataact acaatacttaccggtcaaggaaatacaccagttggtatgtggcactgaaacgaactgggcagtataaacttggatccaaa acaggacctgggcagaaagctatactttttcttccaatgtctgctaagagctgattttaatggccacatctaatctcatt tcacatgaaagaagaagtatattttagaaatttgttaatgagagtaaaagaaaataaatgtgtatagctcagtttggata attggtcaaacaattttttatccagtagtaaaatatgtaaccattgtcccagtaaagaaaaataacaaaagttgtaaaat gtatattctcccttttatattgcatctgctgttacccagtgaagcttacctagagcaatgatctttttcacgcatttgct ttattcgaaaagaggcttttaaaatgtgcatgtttagaaacaaaatttcttcatggaaatcatatacattagaaaatcac agtcagatgtttaatcaatccaaaatgtccactatttcttatgtcattcgttagtctacatgtttctaaacatataaatg tgaatttaatcaattcctttcatagttttataattctctggcagttccttatgatagagtttataaaacagtcctgtgta aactgctggaagttcttccacagtcaggtcaattttgtcaaacccttctctgtacccatacagcagcagcctagcaactc tgctggtgatgggagttgtattttcagtcttcgccaggtcattgagatccatccactcacatcttaagcattcttcctgg caaaaatttatggtgaatgaatatggctttaggcggcagatgatatacatatctgacttcccaaaagctccaggatttgt gtgctgttgccgaatactcaggacggacctgaattctgattttataccagtctcttcaaaaacttctcgaaccgctgtgt ctcctacgtaaaaaaagagatgtacaaatcaataataattacacttttagaaactgtatcatcaaagattttcagttaaa gtagcattatgtaaaggctcaaaacattaccctaacaaagtaaagttttcaatacaaattctttgccttgtggatatcaa gaaatcccaaaatattttcttaccactgtaaattcaagaagcttttgaaatgctgaatatttctttggctgctacttgga ggcttatctacctgtacatttttggggtcagctctttttaacttcttgctgctctttttcccaaaaggtaaaaatataga ttgaaaagttaaaacattttgcatggctgcagttcctttgtttcttgagataagattccaaagaacttagattcatttct tcaacaccgaaatgctggaggtgtttgatcagttttcaagaaacttggaatataaataattttataattcaacaaaggtt ttcacattttataaggttgatttttcaattaaatgcaaatttgtgtggcaggatttttattgccattaacatatttttgt ggctgctttttctacacatccagatggtccctctaactgggctttctctaattttgtgatgttctgtcattgtctcccaa agtatttaggagaagccctttaaaaagctgccttcctctaccactttgctggaaagcttcacaattgtcacagacaaaga tttttgttccaatactcgttttgcctctatttttcttgtttgtcaaatagtaaatgatatttgcccttgcagtaattcta ctggtgaaaaacatgcaaagaagaggaagtcacagaaacatgtctcaattcccatgtgctgtgactgtagactgtcttac catagactgtcttacccatcccctggatatgctcttgttttttccctctaatagctatggaaagatgcatagaaagagta taatgttttaaaacataaggcattcatctgccatttttcaattacatgctgacttcccttacaattgagatttgcccata ggttaaacatggttagaaacaactgaaagcataaaagaaaaatctaggccgggtgcagtggctcatgcctatattccctg cactttgggaggccaaagcaggaggatcgcttgagcccaggagttcaagaccaacctggtgaaaccccgtctctacaaaa aaacacaaaaaatagccaggcatggtggcgtgtacatgtggtctcagatacttgggaggctgaggtgggagggttgatca cttgaggctgagaggtcaaggttgcagtgagccataatcgtgccactgcagtccagcctaggcaacagagtgagactttg tctcaaaaaaagagaaattttccttaataagaaaagtaatttttactctgatgtgcaatacatttgttattaaatttatt atttaagatggtagcactagtcttaaattgtataaaatatcccctaacatgtttaaatgtccatttttattcattatgct ttgaaaaataattatggggaaatacatgtttgttattaaatttattattaaagatagtagcactagtcttaaatttgata taacatctcctaacttgtttaaatgtccatttttattctttatgcttgaaaataaattatggggatcctatttagctctt agtaccactaatcaaaagttcggcatgtagctcatgatctatgctgtttctatgtcgtggaagcaccggatgggggtagt gagcaaatctgccctgctcagcagtcaccatagcagctgactgaaaatcagcactgcctgagtagttttgatcagtttaa cttgaatcactaactgactgaaaattgaatgggcaaataagtgcttttgtctccagagtatgcgggagacccttccacct caagatggatatttcttccccaaggatttcaagatgaattgaaatttttaatcaagatagtgtgctttattctgttgtat tttttattattttaatatactgtaagccaaactgaaataacatttgctgttttataggtttgaagaacataggaaaaact aagaggttttgtttttatttttgctgatgaagagatatgtttaaatatgttgtattgttttgtttagttacaggacaata atgaaatggagtttatatttgttatttctattttgttatatttaataatagaattagattgaaataaaatataatgggaa ataatctgcagaatgtgggtttcctggtgtttcctctgactctagtgcactgatgatctctgataaggctcagctgcttt atagttctctggctaatgcagcagatactcttcctgccagtggtaatacgattttttaagaaggcagtttgtcaatttta atcttgtggatacctttatactcttagggtattattttatacaaaagccttgaggattgcattctattttctatatgacc ctcttgatatttaaaaaacactatggataacaattcttcatttacctagtattatgaaagaatgaaggagttcaaacaaa tgtgtttcccagttaactagggtttactgtttgagccaatataaatgtttaactgtttgtgatggcagtattcctaaagt acattgcatgttttcctaaatacagagtttaaataatttcagtaattcttagatgattcagcttcatcattaagaatatc ttttgttttatgttgagttagaaatgccttcatatagacatagtctttcagacctctactgtcagttttcatttctagct gctttcagggttttatgaattttcaggcaaagctttaatttatactaagcttaggaagtatggctaatgccaacggcagt ttttttct cttaattccacatgactgaggcatatatgatctctgggtaggtgagttgttgtgacaaccacaagcacttt ttttttttttaaagaaaaaaaggtagtgaatttttaatcatctggactttaagaaggattctggagtatacttaggcctg aaattatatatatttggcttggaaatgtgtttttcttcaattacatctacaagtaagtacagctgaaattcagaggaccc ataagagttcacatgaaaaaaatcaattcatttgaaaaggcaagatgcaggagagaggaagccttgcaaacctgcagact gctttttgcccaatatagattgggtaaggctgcaaaacataagcttaattagctcacatgctctgctctcacgtggcacc agtggatagtgtgagagaattaggctgtagaacaaatggccttctctttcagcattcacaccactacaaaatcatctttt atatcaacagaagaataagcataaactaagcaaaaggtcaataagtacctgaaaccaagattggctagagatatatctta atgcaatccattttctgatggattgttacgagttggctatataatgtatgtatggtattttgatttgtgtaaaagtttta aaaatcaagctttaagtacatggacatttttaaataaaatatttaaagacaatttagaaaattgccttaatatcattgtt ggctaaatagaataggggacatgcatattaaggaaaaggtcatggagaaataatattggtatcaaacaaatacattgatt tgtcatgatacacattgaatttgatccaatagtttaaggaataggtaggaaaatttggtttctatttttcgatttcctgt aaatcagtgacataaataattcttagcttattttatatttccttgtcttaaatactgagctcagtaagttgtgttagggg attatttctcagttgagactttcttatatgacattttactatgttttgacttcctgactattaaaaataaatagtagaaa caattttcataaagtgaagaattatataatcactgctttataactgactttattatatttatttcaaagttcatttaaag gctactattcatcctctgtgatggaatggtcaggaatttgttttctcatagtttaattccaacaacaatattagtcgtat ccaaaataacctttaatgctaaactttactgatgtatatccaaagcttctccttttcagacagattaatccagaagcagt cataaacagaagaataggtggtatgttcctaatgatattatttctactaatggaataaactgtaatattagaaattatgc tgctaattatatcagctctgaggtaatttctgaaatgttcagactcagtcggaacaaattggaaaatttaaatttttatt cttagctataaagcaagaaagtaaacacattaatttcctcaacatttttaagccaattaaaaatataaaagatacacacc aatatcttcttcaggctctgacaggcctcctggaaacttccacatatttttcaactgcagtataaagtcagaaaataaag ttaacataactttcactaacacacacatatgtagatttcacaaaatccacctataattggtcaaagtggttgagaatata ttttttagtaattgcatgcaaaatttttctagcttccatcctttctccctcgtttcttctttttttgggggagctggtaa ctgatgaaatcttttcccaccttttctcttcaggaaatataagtggttttgtttggttaacgtgatacattctgtatgaa tgaaacattggagggaaacatctactgaatttctgtaatttaaaatattttgctgctagttaactatgaacagatagaag aatcttacagatgctgctataaataagtagaaaatataaatttcatcactaaaatatgctattttaaaatctatttccta tattgtatttctaatcagatgtattactcttattatttctattgtatgtgttaatgattttatgtaaaaatgtaattgct tttcatgagtagtatgaataaaattgattagtttgtg (SEQ ID NO:12032) cagtgagctgtgattgcaccactgcaatttagcctgagtgacagaatgaaaaaaaaatttttttaaaggaaaacacaaaa agaatatgctgtcaacagggatgggaggaagaccacctttactgctatacacatttgtaccttttagatgttgatcaata tgaatatattatacacacagacacacacacagacacacacacacacacaaacaatacaatttaatatcctaagaggatat tgacattagacaggtacaaaagctctagaaatgaggactttcctcagtgatgacttttttcaccaccaaagtcactcagg catcctgacaagggtaagtgaggggagcctccttggaaaataaactcacttggatagtgaactcctgcacatacctcaaa gcccatctgaaatgtcccctcctacaggaagttttccctgaccctccaagaagcagagttctatttcactggggaaaaca tttcttcttcttcttttttttccctgccctgcacatgagctagaaaacatttcatgaaactgggagtttctgtgctgggc tctgtccctcccccattctacttcccctccctcagcatggaagcctctggaagtggggctctgactcccagcctacagag agattcctaggaagtgttcgactgataaacgcatggccaaaagtgaactggggatgaggtccaagacatctgcggtgggg ggttctccagaccttagtgttcttccactacaaagtgggtccaacagagaaaggtctgtgttcaccaggtggccctgacc ctgggagagtccagggcagggtgcagctgcattcatgctgctggggaacatgccctcaggttactcaccccatggacatg ttggccccagggactgaaaagcttaggaaatggtattgagaaatctggggcagccccaaaaggggagaggccatggggag aagggggggctgagtgggggaaaggcaggagccagataaaaagccagctccagcaggcgctgctcactcctccccatcct ctccctctgtccctctgtccctctgaccctgcactgtcccagcaccatg (SEQ ID NO:12033) tttctcccattctacttccctcctcagcattggaagctcgtaagtgggctctgactcccagcctacagagagattcctta agaagtggttcgactgataaacgcattgccaaaagtgaactgggatgaggtccaagacatctgcggtgggggttctccag accttagtgttcttccactacaaagtgggtccaacagagaaaggtctgtgttcaccaggtggccctgaccctggagagtc cagggcagggtgcagctgcattcatgctgctggggaacatgccctcaggttactcaccccatgacatgttggccccaggg actgaaaagcttaggaaatggtattgagaaatctggggcagccaaaaggggagaggccatggggagaagggggggctgag tgggggaaagcaggagcgagataaaaagccagctccagcaggcgctgctcactcctccccatcctctccctctgtccctc tgtccctctgaccctgcactgtcccagcaccatgggacccacctcaggtcccagcctgctgctcctgctactaacccacc tccccctggctctggggagtcccatgtactctatcatcacccccaacatcttgcggctggagagcgaggagaccatggtg ctggaggcccacgacgcgcaaggggatgttccagtcactgttactgtccacgacttcccaggcaaaaaactagtgctgtc cagtgagaagactgtgctgacccctgccaccaaccacatgggcaacgtcaccttcacgatcccagccaacagggagttca agtcagaaaaggggcgcaacaagttcgtgaccgtgcaggccaccttcgggacccaagtggtggagaaggtggtgctggtc agcctgcagagcgggtacctcttcat cagacagacaagaccatctacacccctggctccacagttctctatcggatctt caccgtcaaccacaagctgctacccgtgggccggacggtcatggtcaacattgagaacccggaaggcatcccggtcaagc aggactccttgtcttctcagaaccagcttggcgtcttgcccttgtcttgggacattccggaactcgtcaacatgggccag tggaagatccgagcctactatgaaaactcaccacagcaggtcttctccactgagtttgaggtgaaggagtacgtgctgcc cagtttcgaggtcatagtggagcctacagagaaattctactacatctataacgagaagggcctggaggtcaccatcaccg ccaggttcctctacgggaagaaagtggagggaactgcctttgtcatcttcgggatccaggatggcgaacagaggatttcc ctgcctgaatccctcaagcgcattccgattgaggatggctcgggggaggttgtgctgagccggaaggtactgctggacgg ggtgcagaacctccgagcagaagacctggtggggaagtctttgtacgtgtctgccaccgtcatcttgcactcaggcagtg acatggtgcaggcagagcgcagcgggatccccatcgtgacctctccctaccagatccacttcaccaagacacccaagtac ttcaaaccaggaatgccctttgacctcatggtgttcgtgacgaaccctgatggctctccagcctaccgagtccccgtggc agtccagggcgaggacactgtgcagtctctaacccagggagatggcgtggccaaactcagcatcaacacacaccccagcc agaagcccttgagcatcacggtgcgcacgaagaagcaggagctctcggaggcagagcaggctaccaggaccatgcaggct ctgccctacagcaccgtgggcaactccaacaattacctgcatctctcagtgctacgtacagagctcagacccggggagac cctcaacgtcaacttcctcctgcgaatggaccgcgcccacgaggccaagatccgctactacacctacctgatcatgaaca agggcaggctgttgaaggcgggacgccaggtgcgagagcccggccaggacctggtggtgctgcccctgtccatcaccacc gacttcatcccttccttccgcctggtggcgtactacacgctgatcggtgccagcggccagagggaggtggtggccgactc cgtgtgggtggacgtcaaggactcctgcgtgggctcgctggtggtaaaaagcggccagtcagaagaccggcagcctgtac ctgggcagcagatgaccctgaagatagagggtgaccacggggcccgggtggtactggtggccgtggacaagggcgtgttc gtgctgaataagaagaacaaactgacgcagagtaagatctgggacgtggtggagaaggcagacatcggctgcaccccggg cagtgggaaggattacgccggtgtcttctccgacgcagggctgaccttcacgagcagcagtggccagcagaccgcccaga gggcagaacttcagtgcccgcagccagccgcccgccgacgccgttccgtgcagctcacggagaagcgaatggacaaagtc ggcaagtaccccaaggagctgcgcaagtgctgcgaggacggcatgcgggagaaccccatgaggttctcgtgccagcgccg gacccgtttcatctccctgggcgaggcgtgcaagaaggtcttcctggactgctgcaactacatcacagagctgcggcggc agcacgcgcgggccagccacctgggcctggccaggagtaacctggatgaggacatcattgcagaagagaacatcgtttcc cgaagtgagttcccagagagctggctgtggaacgttgaggacttgaaagagccaccgaaaaatggaatctctacgaagct catgaatatatttttgaaagactccatcaccacgtgggagattctggctgtcagcatgtcggacaagaaagggatctgtg tggcagaccccttcgaggtcacagtaatgcaggacttcttcatcgacctgcggctaccctactctgttgttcgaaacgag caggtggaaatccgagccgttctctacaattaccggcagaaccaagagctcaaggtgagggtggaactactccacaatcc agccttctgcagcctggccaccaccaagaggcgtcaccagcagaccgtaaccatcccccccaagtcctcgttgtccgttc catatgtcatcgtgccgctaaagaccggcctgcaggaagtggaagtcaaggctgccgtctaccatcatttcatcagtgac ggtgtcaggaagtccctgaaggtcgtgccggaaggaatcagaatgaacaaaactgtggctgttcgcaccctggatccaga acgcctgggccgtgaaggagtgcagaaagaggacatcccacctgcagacctcagtgaccaagtcccggacaccgagtctg agaccagaattctcctgcaagggaccccagtggcccagatgacagaggatgccgtcgacgcggaacggctgaagcacctc attgtgaccccctcgggctgcggggaacagaacatgatcggcatgacgcccacggtcatcgctgtgcattacctggatga aacggagcagtgggagaagttcggcctagagaagcggcagggggccttggagctcatcaagaaggggtacacccagcagc tggccttcagacaacccagctctgcctttgcggccttcgtgaaacgggcacccagcacctggctgaccgcctacgtggtc aaggtcttctctctggctgtcaacctcatcgccatcgactcccaagtcctctgcggggctgttaaatggctgatcctgga gaagcagaagcccgacggggtcttccaggaggatgcgcccgtgatacaccaagaaatgattggtggattacggaacaaca acgagaaagacatggccctcacggcctttgttctcatctcgctgcaggaggctaaagatatttgcgaggagcaggtcaac agcctgccaggcagcatcactaaagcaggagacttccttgaagccaactacatgaacctacagagatcctacactgtggc cattgctggctatgctctggcccagatgggcaggctgaaggggcctcttcttaacaaatttctgaccacagccaaagata agaaccgctgggaggaccctggtaagcagctctacaacgtggaggccacatcctatgccctcttggccctactgcagcta aaagactttgactttgtgcctcccgtcgtgcgttggctcaatgaacagagatactacggtggtggctatggctctaccca ggccaccttcatggtgttccaagccttggctcaataccaaaaggacgcccctgaccaccaggaactgaaccttgatgtgt ccctccaactgcccagccgcagctccaagatcacccaccgtatccactgggaatctgccagcctcctgcgatcagaagag accaaggaaaatgagggtttcacagtcacagctgaaggaaaaggccaaggcaccttgtcggtggtgacaatgtaccatgc taaggccaaagatcaactcacctgtaataaattcgacctcaaggtcaccataaaaccagcaccggaaacagaaaagaggc ctcaggatgccaagaacactatgatccttgagatctgtaccaggtaccggggagaccaggatgccactatgtctatattg gacatatccatgatgactggctttgctccagacacagatgacctgaagcagctggccaatggtgttgacagatacatctc caagtatgagctggacaaagccttctccgataggaacaccctcatcatctacctggacaaggtctcacactctgaggatg actgtctagctttcaaagttcaccaatactttaatgtagagcttatccagcctggagcagtcaaggtctacgcctattac aacctggaggaaagctgtacccggttctaccatccggaaaaggaggatggaaagctgaacaagctctgccgtgatgaact gtgccgctgtgctgaggagaattgcttcatacaaaagtcggatgacaaggtcaccctggaagaacggctggacaaggcct gtgagccaggagtggactatgtgtacaagacccgactggtcaaggttcagctgtccaatgactttgacgagtacatcatg gccattgagcagaccatcaagtcaggctcggatgaggtgcaggttggacagcagcgcacgttcatcagccccatcaagtg cagagaagccctgaagctggaggagaagaaacactacctcatgtggggtctctcctccgatttctggggagagaagccca acctcagctacatcatcgggaaggacacttgggtggagcactggcctgaggaggacgaatgccaagacgaagagaaccag aaacaatgccaggacctcggcgccttcaccgagagcatggttgtctttgggtgccccaactgaccacacccccattccat gaacctacagagatcctacactgtggccattgctggctatgctctggcccagatgggcaggctgaaggggcctcttctta acaaatttctgaccacagccaaagataagaaccgctgggaggaccctggtaagcagctctacaacgtggaggccacatcc tatgccctcttggccctactgcagctaaaagactttgactttgtgcctcccgtcgtgcgttggctcaatgaacagagata ctacggtggtggctatggctctacccaggccaccttcatggtgttccaagccttggctcaataccaaaaggacgcccctg accaccaggaactgaaccttgatgtgtccctccaactgcccagccgcagctccaagatcacccaccgtatccactgggaa tctgccagcctcctgcgatcagaagag (SEQ ID NO: 12034) ctcctccccatcctctccctctgtccctctgtccctctgaccctgcactgtcccagcaccatgggacccacctcaggtcc cagcctgctgctcctgctactaacccacctccccctggctctggggagtcccatgtactctatcatcacccccaacatct tgcggctggagagcgaggagaccatggtgctggaggcccacgacgcgcaaggggatgttccagtcactgttactgtccac gacttcccaggcaaaaaactagtgctgtccagtgagaagactgtgctgacccctgccaccaaccacatgggcaacgtcac cttcacgatcccagccaacagggagttcaagtcagaaaaggggcgcaacaagttcgtgaccgtgcaggccaccttcggga cccaagtggtggagaaggtggtgctggtcagcctgcagagcgggtacctcttcatccagacagacaagaccatctacacc cctggctccacagttctctatcggatcttcaccgtcaaccacaagctgctacccgtgggccggacggtcatggtcaacat tgagaacccggaaggcatcccggtcaagcaggactccttgtcttctcagaaccagcttggcgtcttgcccttgtcttggg acattccggaactcgtcaacatgggccagtggaagatccgagcctactatgaaaactcaccacagcaggtcttctccact gagtttgaggtgaaggagtacgtgctgcccagtttcgaggtcatagtggagcctacagagaaattctactacatctataa cgagaagggcctggaggtcaccatcaccgccaggttcctctacgggaagaaagtggagggaactgcctttgtcatcttcg ggatccaggatggcgaacagaggatttccctgcctgaatccctcaagcgcattccgattgaggatggctcgggggaggtt gtgctgagccggaaggtactgctggacggggtgcagaacctccgagcagaagacctggtggggaagtctttgtacgtgtc tgccaccgtcatcttgcactcaggcagtgacatggtgcaggcagagcgcagcgggatccccatcgtgacctctccctacc agatccacttcaccaagacacccaagtacttcaaaccaggaatgccctttgacctcatggtgttcgtgacgaaccctgat ggctctccagcctaccgagtccccgtggcagtccagggcgaggacactgtgcagtctctaacccagggagatggcgtggc caaactcagcatcaacacacaccccagccagaagcccttgagcatcacggtgcgcacgaagaagcaggagctctcggagg cagagcaggctaccaggaccatgcaggctctgccctacagcaccgtgggcaactccaacaattacctgcatctctcagtg ctacgtacagagctcagacccggggagaccctcaacgtcaacttcctcctgcgaatggaccgcgcccacgaggccaagat ccgctactacacctacctgatcatgaacaagggcaggctgttgaaggcgggacgccaggtgcgagagcccggccaggacc tggtggtgctgcccctgtccatcaccaccgacttcatcccttccttccgcctggtggcgtactacacgctgatcggtgcc agcggccagagggaggtggtggccgactccgtgtgggtggacgtcaaggactcctgcgtgggctcgctggtggtaaaaag cggccagtcagaagaccggcagcctgtacctgggcagcagatgaccctgaagatagagggtgaccacggggcccgggtgg tactggtggccgtggacaagggcgtgttcgtgctgaataagaagaacaaactgacgcagagtaagatctgggacgtggtg gagaaggcagacatcggctgcaccccgggcagtgggaaggattacgccggtgtcttctccgacgcagggctgaccttcac gagcagcagtggccagcagaccgcccagagggcagaacttcagtgcccgcagccagccgcccgccgacgccgttccgtgc agctcacggagaagcgaatggacaaagtcggcaagtaccccaaggagctgcgcaagtgctgcgaggacggcatgcgggag aaccccatgaggttctcgtgccagcgccggacccgtttcatctccctgggcgaggcgtgcaagaaggtcttcctggactg ctgcaactacatcacagagctgcggcggcagcacgcgcgggccagccacctgggcctggccaggagtaacctggatgagg acatcattgcagaagagaacatcgtttcccgaagtgagttcccagagagctggctgtggaacgttgaggacttgaaagag ccaccgaaaaatggaatctctacgaagctcatgaatatatttttgaaagactccatcaccacgtgggagattctggctgt cagcatgtcggacaagaaagggatctgtgtggcagaccccttcgaggtcacagtaatgcaggacttcttcatcgacctgc ggctaccctactctgttgttcgaaacgagcaggtggaaatccgagccgttctctacaattaccggcagaaccaagagctc aaggtgagggtggaactactccacaatccagccttctgcagcctggccaccaccaagaggcgtcaccagcagaccgtaac catcccccccaagtcctcgttgtccgttccatatgtcatcgtgccgctaaagaccggcctgcaggaagtggaagtcaagg ctgccgtctaccatcatttcatcagtgacggtgtcaggaagtccctgaaggtcgtgccggaaggaatcagaatgaacaaa actgtggctgttcgcaccctggatccagaacgcctgggccgtgaaggagtgcagaaagaggacatcccacctgcagacct cagtgaccaagtcccggacaccgagtctgagaccagaattctcctgcaagggaccccagtggcccagatgacagaggatg ccgtcgacgcggaacggctgaagcacctcattgtgaccccctcgggctgcggggaacagaacatgatcggcatgacgccc acggtcatcgctgtgcattacctggatgaaacggagcagtgggagaagttcggcctagagaagcggcagggggccttgga gctcatcaagaaggggtacacccagcagctggccttcagacaacccagctctgcctttgcggccttcgtgaaacgggcac ccagcacctggctgaccgcctacgtggtcaaggtcttctctctggctgtcaacctcatcgccatcgactcccaagtcctc tgcggggctgttaaatggctgatcctggagaagcagaagcccgacggggtcttccaggaggatgcgcccgtgatacacca agaaatgattggtggattacggaacaacaacgagaaagacatggccctcacggcctttgttctcatctcgctgcaggagg ctaaagatatttgcgaggagcaggtcaacagcctgccaggcagcatcactaaagcaggagacttccttgaagccaactac atgaacctacagagatcctacactgtggccattgctggctatgctctggcccagatgggcaggctgaaggggcctc tct taacaaatttctgaccacagccaaagataagaaccgctgggaggaccctggtaagcagctctacaacgtggaggccacat cctatgccctcttggccctactgcagctaaaagactttgactttgtgcctcccgtcgtgcgttggctcaatgaacagaga tactacggtggtggctatggctctacccaggccaccttcatggtgttccaagccttggctcaataccaaaaggacgcccc tgaccaccaggaactgaaccttgatgtgtccctccaactgcccagccgcagctccaagatcacccaccgtatccactggg aatctgccagcctcctgcgatcagaagagaccaaggaaaatgagggtttcacagtcacagctgaaggaaaaggccaaggc accttgtcggtggtgacaatgtaccatgctaaggccaaagatcaactcacctgtaataaattcgacctcaaggtcaccat aaaaccagcaccggaaacagaaaagaggcctcaggatgccaagaacactatgatccttgagatctgtaccaggtaccggg gagaccaggatgccactatgtctatattggacatatccatgatgactggctttgctccagacacagatgacctgaagcag ctggccaatggtgttgacagatacatctccaagtatgagctggacaaagccttctccgataggaacaccctcatcatcta cctggacaaggtctcacactctgaggatgactgtctagctttcaaagttcaccaatactttaatgtagagcttatccagc ctggagcagtcaaggtctacgcctattacaacctggaggaaagctgtacccggttctaccatccggaaaaggaggatgga aagctgaacaagctctgccgtgatgaactgtgccgctgtgctgaggagaattgcttcatacaaaagtcggatgacaaggt caccctggaagaacggctggacaaggcctgtgagccaggagtggactatgtgtacaagacccgactggtcaaggttcagc tgtccaatgactttgacgagtacatcatggccattgagcagaccatcaagtcaggctcggatgaggtgcaggttggacag cagcgcacgttcatcagccccatcaagtgcagagaagccctgaagctggaggagaagaaacactacctcatgtggggtct ctcctccgatttctggggagagaagcccaacctcagctacatcatcgggaaggacacttgggtggagcactggcctgagg aggacgaatgccaagacgaagagaaccagaaacaatgccaggacctcggcgccttcaccgagagcatggttgtctttggg tgccccaactgaccacacccccattcc (SEQ ID NO: 12035) cagtgagctgtgattgcaccactgcaatttagcctgagtgacagaatgaaaaaaaaatttttttaaaggaaaacacaaaa agaatatgctgtcaacagggatgggaggaagaccacctttactgctatacacatttgtaccttttagatgttgatcaata tgaatatattatacacacagacacacacacagacacacacacacacacaaacaatacaatttaatatcctaagaggatat tgacattagacaggtacaaaagctctagaaatgaggactttcctcagtgatgacttttttcaccaccaaagtcactcagg ca cctgacaagggtaagtgaggggagcctccttggaaaataaactcacttggatagtgaactcctgcacatacctcaaa gcccatctgaaatgtcccctcctacaggaagttttccctgaccctccaagaagcagagttctatttcactggggaaaaca tttcttcttcttcttttttttccctgccctgcacatgagctagaaaacatttcatgaaactgggagtttctgtgctgggc tctgtccctcccccattctacttcccctccctcagcatggaagcctctggaagtggggctctgactcccagcctacagag agattcctaggaagtgttcgactgataaacgcatggccaaaagtgaactggggatgaggtccaagacatctgcggtgggg ggttctccagaccttagtgttcttccactacaaagtgggtccaacagagaaaggtctgtgttcaccaggtggccctgacc ctgggagagtccagggcagggtgcagctgcattcatgctgctggggaacatgccctcaggttactcaccccatggacatg ttggccccagggactgaaaagcttaggaaatggtattgagaaatctggggcagccccaaaaggggagaggccatggggag aagggggggctgagtgggggaaaggcaggagccagataaaaagccagctccagcaggcgctgctcactcctccccatcct ctccctctgtccctctgtccctctgaccctgcactgtcccagcaccatgtttctcccattctacttccctcctcagcatt ggaagctcgtaagtgggctctgactcccagcctacagagagattccttaagaagtggttcgactgataaacgcattgcca aaagtgaactgggatgaggtccaagacatctgcggtgggggttctccagaccttagtgttcttccactacaaagtgggtc caacagagaaaggtctgtgttcaccaggtggccctgaccctggagagtccagggcagggtgcagctgcattcatgctgct ggggaacatgccctcaggtt ctcaccccatgacatgttggccccagggactgaaaagcttaggaaatggtattgagaaa tctggggcagccaaaaggggagaggccatggggagaagggggggctgagtgggggaaagcaggagcgagataaaaagcca gctccagcaggcgctgctcactcctccccatcctctccctctgtccctctgtccctctgaccctgcactgtcccagcacc atgggacccacctcaggtcccagcctgctgctcctgctactaacccacctccccctggctctggggagtcccatgtactc tatcatcacccccaacatcttgcggctggagagcgaggagaccatggtgctggaggcccacgacgcgcaaggggatgttc cagtcactgttactgtccacgacttcccaggcaaaaaactagtgctgtccagtgagaagactgtgctgacccctgccacc aaccacatgggcaacgtcaccttcacgatcccagccaacagggagttcaagtcagaaaaggggcgcaacaagttcgtgac cgtgcaggccaccttcgggacccaagtggtggagaaggtggtgctggtcagcctgcagagcgggtacctcttcatccaga cagacaagaccatctacacccctggctccacagttctctatcggatcttcaccgtcaaccacaagctgctacccgtgggc cggacggtcatggtcaacattgagaacccggaaggcatcccggtcaagcaggactccttgtcttctcagaaccagcttgg cgtcttgcccttgtcttgggacattccggaactcgtcaacatgggccagtggaagatccgagcctactatgaaaactcac cacagcaggtcttctccactgagtttgaggtgaaggagtacgtgctgcccagtttcgaggtcatagtggagcctacagag aaattctactacatctataacgagaagggcctggaggtcaccatcaccgccaggttcctctacgggaagaaagtggaggg aactgcctttgtcatcttcgggatccaggatggcgaacagaggatttccctgcctgaatccctcaagcgcattccgattg aggatggctcgggggaggttgtgctgagccggaaggtactgctggacggggtgcagaacctccgagcagaagacctggtg gggaagtctttgtacgtgtctgccaccgtcatcttgcactcaggcagtgacatggtgcaggcagagcgcagcgggatccc catcgtgacctctccctaccagatccacttcaccaagacacccaagtacttcaaaccaggaatgccctttgacctcatgg tgttcgtgacgaaccctgatggctctccagcctaccgagtccccgtggcagtccagggcgaggacactgtgcagtctcta acccagggagatggcgtggccaaactcagcatcaacacacaccccagccagaagcccttgagcatcacggtgcgcacgaa gaagcaggagctctcggaggcagagcaggctaccaggaccatgcaggctctgccctacagcaccgtgggcaactccaaca attacctgcatctctcagtgctacgtacagagctcagacccggggagaccctcaacgtcaacttcctcctgcgaatggac cgcgcccacgaggccaagatccgctactacacctacctgatcatgaacaagggcaggctgttgaaggcgggacgccaggt gcgagagcccggccaggacctggtggtgctgcccctgtccatcaccaccgacttcatcccttccttccgcctggtggcgt actacacgctgatcggtgccagcggccagagggaggtggtggccgactccgtgtgggtggacgtcaaggactcctgcgtg ggctcgctggtggtaaaaagcggccagtcagaagaccggcagcctgtacctgggcagcagatgaccctgaagatagaggg tgaccacggggcccgggtggtactggtggccgtggacaagggcgtgttcgtgctgaataagaagaacaaactgacgcaga gtaagatctgggacgtggtggagaaggcagacatcggctgcaccccgggcagtgggaaggattacgccggtgtcttctcc gacgcagggctgaccttcacgagcagcagtggccagcagaccgcccagagggcagaacttcagtgcccgcagccagccgc ccgccgacgccgttccgtgcagctcacggagaagcgaatggacaaagtcggcaagtaccccaaggagctgcgcaagtgct gcgaggacggcatgcgggagaaccccatgaggt ctcgtgccagcgccggacccgtttcatctccctgggcgaggcgtgc aagaaggtcttcctggactgctgcaactacatcacagagctgcggcggcagcacgcgcgggccagccacctgggcctggc caggagtaacctggatgaggacatcattgcagaagagaacatcgtttcccgaagtgagttcccagagagctggctgtgga acgttgaggacttgaaagagccaccgaaaaatggaatctctacgaagctcatgaatatatttttgaaagactccatcacc acgtgggagattctggctgtcagcatgtcggacaagaaagggatctgtgtggcagaccccttcgaggtcacagtaatgca ggacttcttcatcgacctgcggctaccctactctgttgttcgaaacgagcaggtggaaatccgagccgttctctacaatt accggcagaaccaagagctcaaggtgagggtggaactactccacaatccagccttctgcagcctggccaccaccaagagg cgtcaccagcagaccgtaaccatcccccccaagtcctcgttgtccgttccatatg ca cgtgccgctaaagaccggcct gcaggaagtggaagtcaaggctgccgtctaccatcatttcatcagtgacggtgtcaggaagtccctgaaggtcgtgccgg aaggaatcagaatgaacaaaactgtggctgttcgcaccctggatccagaacgcctgggccgtgaaggagtgcagaaagag gacatcccacctgcagacctcagtgaccaagtcccggacaccgagtctgagaccagaattctcctgcaagggaccccagt ggcccagatgacagaggatgccgtcgacgcggaacggctgaagcacctcattgtgaccccctcgggctgcggggaacaga acatgatcggcatgacgcccacggtcatcgctgtgcattacctggatgaaacggagcagtgggagaagttcggcctagag aagcggcagggggccttggagctcatcaagaaggggtacacccagcagctggccttcagacaacccagctctgcctttgc ggccttcgtgaaacgggcacccagcacctggctgaccgcctacgtggtcaaggtcttctctctggctgtcaacctcatcg ccatcgactcccaagtcctctgcggggctgttaaatggctgatcctggagaagcagaagcccgacggggtcttccaggag gatgcgcccgtgatacaccaagaaatgattggtggattacggaacaacaacgagaaagacatggccctcacggcctttgt tctcatctcgctgcaggaggctaaagatatttgcgaggagcaggtcaacagcctgccaggcagcatcactaaagcaggag acttccttgaagccaactacatgaacctacagagatcctacactgtggccattgctggctatgctctggcccagatgggc aggctgaaggggcctcttcttaacaaatttctgaccacagccaaagataagaaccgctgggaggaccctggtaagcagct ctacaacgtggaggccacatcctatgccctcttggccctactgcagctaaaagactttgactttgtgcctcccgtcgtgc gttggctcaatgaacagagatactacggtggtggctatggctctacccaggccaccttcatggtgttccaagccttggct caataccaaaaggacgcccctgaccaccaggaactgaaccttgatgtgtccctccaactgcccagccgcagctccaagat cacccaccgtatccactgggaatctgccagcctcctgcgatcagaagagaccaaggaaaatgagggtttcacagtcacag ctgaaggaaaaggccaaggcaccttgtcggtggtgacaatgtaccatgctaaggccaaagatcaactcacctgtaataaa ttcgacctcaaggtcaccataaaaccagcaccggaaacagaaaagaggcctcaggatgccaagaacactatgatccttga gatctgtaccaggtaccggggagaccaggatgccactatgtctatattggacatatccatgatgactggctttgctccag acacagatgacctgaagcagctggccaatggtgttgacagatacatctccaagtatgagctggacaaagccttctccgat aggaacaccctcatcatctacctggacaaggtctcacactctgaggatgactgtctagctttcaaagttcaccaatactt taatgtagagcttatccagcctggagcagtcaaggtctacgcctattacaacctggaggaaagctgtacccggttctacc atccggaaaaggaggatggaaagctgaacaagctctgccgtgatgaactgtgccgctgtgctgaggagaattgcttcata caaaagtcggatgacaaggtcaccctggaagaacggctggacaaggcctgtgagccaggagtggactatgtgtacaagac ccgactggtcaaggttcagctgtccaatgactttgacgagtacatcatggccattgagcagaccatcaagtcaggctcgg atgaggtgcaggttggacagcagcgcacgttcatcagccccatcaagtgcagagaagccctgaagctggaggagaagaaa cactacctcatgtggggtctctcctccgatttctggggagagaagcccaacctcagctacatcatcgggaaggacacttg ggtggagcactggcctgaggaggacgaatgccaagacgaagagaaccagaaacaatgccaggacctcggcgccttcaccg agagcatggttgtctttgggtgccccaactgaccacacccccattccatgaacctacagagatcctacactgtggccatt gctggctatgctctggcccagatgggcaggctgaaggggcctcttcttaacaaatttctgaccacagccaaagataagaa ccgctgggaggaccctggtaagcagctctacaacgtggaggccacatcctatgccctcttggccctactgcagctaaaag actttgactttgtgcctcccgtcgtgcgttggctcaatgaacagagatactacggtggtggctatggctctacccaggcc accttcatggtgttccaagccttggctcaataccaaaaggacgcccctgaccaccaggaactgaaccttgatgtgtccct ccaactgcccagccgcagctccaagatcacccaccgtatccactgggaatctgccagcctcctgcgatcagaagagctcc tccccatcctctccctctgtccctctgtccctctgaccctgcactgtcccagcaccatgggacccacctcaggtcccagc ctgctgctcctgctactaacccacctccccctggctctggggagtcccatgtactctatcatcacccccaacatcttgcg gctggagagcgaggagaccatggtgctggaggcccacgacgcgcaaggggatgttccagtcactgttactgtccacgact tcccaggcaaaaaactagtgctgtccagtgagaagactgtgctgacccctgccaccaaccacatgggcaacgtcaccttc acgatcccagccaacagggagttcaagtcagaaaaggggcgcaacaagttcgtgaccgtgcaggccaccttcgggaccca agtggtggagaaggtggtgctggtcagcctgcagagcgggtacctcttcatccagacagacaagaccatctacacccctg gctccacagttctctatcggatcttcaccgtcaaccacaagctgctacccgtgggccggacggtcatggtcaacattgag aacccggaaggcatcccggtcaagcaggactccttgtcttctcagaaccagcttggcgtcttgcccttgtcttgggacat tccggaactcgtcaacatgggccagtggaagatccgagcctactatgaaaactcaccacagcaggtcttctccactgagt ttgaggtgaaggagtacgtgctgcccagtttcgaggtcatagtggagcctacagagaaattctactacatctataacgag aagggcctggaggtcaccatcaccgccaggttcctctacgggaagaaagtggagggaactgcctttgtcatcttcgggat ccaggatggcgaacagaggatttccctgcctgaatccctcaagcgcattccgattgaggatggctcgggggaggttgtgc tgagccggaaggtactgctggacggggtgcagaacctccgagcagaagacctggtggggaagtctttgtacgtgtctgcc accgtcatcttgcactcaggcagtgacatggtgcaggcagagcgcagcgggatccccatcgtgacctctccctaccagat ccacttcaccaagacacccaagtacttcaaaccaggaatgccctttgacctcatggtgttcgtgacgaaccctgatggct ctccagcctaccgagtccccgtggcagtccagggcgaggacactgtgcagtctctaacccagggagatggcgtggccaaa ctcagcatcaacacacaccccagccagaagcccttgagcatcacggtgcgcacgaagaagcaggagctctcggaggcaga gcaggctaccaggaccatgcaggctctgccctacagcaccgtgggcaactccaacaattacctgcatctctcagtgctac gtacagagctcagacccggggagaccctcaacgtcaacttcctcctgcgaatggaccgcgcccacgaggccaagatccgc tactacacctacctgatcatgaacaagggcaggctgttgaaggcgggacgccaggtgcgagagcccggccaggacctggt ggtgctgcccctgtccatcaccaccgacttcatcccttccttccgcctggtggcgtactacacgctgatcggtgccagcg gccagagggaggtggtggccgactccgtgtgggtggacgtcaaggactcctgcgtgggctcgctggtggtaaaaagcggc cagtcagaagaccggcagcctgtacctgggcagcagatgaccctgaagatagagggtgaccacggggcccgggtggtact ggtggccgtggacaagggcgtgttcgtgctgaataagaagaacaaactgacgcagagtaagatctgggacgtggtggaga aggcagacatcggctgcaccccgggcagtgggaaggattacgccggtgtcttctccgacgcagggctgaccttcacgagc agcagtggccagcagaccgcccagagggcagaacttcagtgcccgcagccagccgcccgccgacgccgttccgtgcagct cacggagaagcgaatggacaaagtcggcaagtaccccaaggagctgcgcaagtgctgcgaggacggcatgcgggagaacc ccatgaggttctcgtgccagcgccggacccgtttcatctccctgggcgaggcgtgcaagaaggtcttcctggactgctgc aactacatcacagagctgcggcggcagcacgcgcgggccagccacctgggcctggccaggagtaacctggatgaggacat cattgcagaagagaacatcgtttcccgaagtgagttcccagagagctggctgtggaacgttgaggacttgaaagagccac cgaaaaatggaatctctacgaagctcatgaatatatttttgaaagactccatcaccacgtgggagattctggctgtcagc atgtcggacaagaaagggatctgtgtggcagaccccttcgaggtcacagtaatgcaggacttcttcatcgacctgcggct accctactctgttgttcgaaacgagcaggtggaaatccgagccgttctctacaattaccggcagaaccaagagctcaagg tgagggtggaactactccacaatccagccttctgcagcctggccaccaccaagaggcgtcaccagcagaccgtaaccatc ccccccaagtcctcgttgtccgttccatatgtcatcgtgccgctaaagaccggcctgcaggaagtggaagtcaaggctgc cgtctaccatcatttcatcagtgacggtgtcaggaagtccctgaaggtcgtgccggaaggaatcagaatgaacaaaactg tggctgttcgcaccctggatccagaacgcctgggccgtgaaggagtgcagaaagaggacatcccacctgcagacctcagt gaccaagtcccggacaccgagtctgagaccagaa tctcctgcaagggaccccagtggcccagatgacagaggatgccgt cgacgcggaacggctgaagcacctcattgtgaccccctcgggctgcggggaacagaacatgatcggcatgacgcccacgg tcatcgctgtgcattacctggatgaaacggagcagtgggagaagttcggcctagagaagcggcagggggccttggagctc atcaagaaggggtacacccagcagctggccttcagacaacccagctctgcctttgcggccttcgtgaaacgggcacccag cacctggctgaccgcctacgtggtcaaggtcttctctctggctgtcaacctcatcgccatcgactcccaagtcctctgcg gggctgttaaatggctgatcctggagaagcagaagcccgacggggtcttccaggaggatgcgcccgtgatacaccaagaa atgattggtggattacggaacaacaacgagaaagacatggccctcacggcctttgttctcatctcgctgcaggaggctaa agatatttgcgaggagcaggtcaacagcctgccaggcagcatcactaaagcaggagacttccttgaagccaactacatga acctacagagatcctacactgtggccattgctggctatgctctggcccagatgggcaggctgaaggggcctcttcttaac aaatttctgaccacagccaaagataagaaccgctgggaggaccctggtaagcagctctacaacgtggaggccacatccta tgccctcttggccctactgcagctaaaagactttgactttgtgcctcccgtcgtgcgttggctcaatgaacagagatact acggtggtggctatggctctacccaggccaccttcatggtgttccaagccttggctcaataccaaaaggacgcccctgac caccaggaactgaaccttgatgtgtccctccaactgcccagccgcagctccaagatcacccaccgtatccactgggaatc tgccagcctcctgcgatcagaagagaccaaggaaaatgagggtttcacagtcacagctgaaggaaaaggccaaggcacct tgtcggtggtgacaatgtaccatgctaaggccaaagatcaactcacctgtaataaattcgacctcaaggtcaccataaaa ccagcaccggaaacagaaaagaggcctcaggatgccaagaacactatgatccttgagatctgtaccaggtaccggggaga ccaggatgccactatgtctatattggacatatccatgatgactggctttgctccagacacagatgacctgaagcagctgg ccaatggtgttgacagatacatctccaagtatgagctggacaaagccttctccgataggaacaccctcatcatctacctg gacaaggtctcacactctgaggatgactgtctagctttcaaagttcaccaatactttaatgtagagcttatccagcctgg agcagtcaaggtctacgcctattacaacctggaggaaagctgtacccggttctaccatccggaaaaggaggatggaaagc tgaacaagctctgccgtgatgaactgtgccgctgtgctgaggagaattgcttcatacaaaagtcggatgacaaggtcacc ctggaagaacggctggacaaggcctgtgagccaggagtggactatgtgtacaagacccgactggtcaaggttcagctgtc caatgactttgacgagtacatcatggccattgagcagaccatcaagtcaggctcggatgaggtgcaggttggacagcagc gcacgttcatcagccccatcaagtgcagagaagccctgaagctggaggagaagaaacactacctcatgtggggtctctcc tccgatttctggggagagaagcccaacctcagctacatcatcgggaaggacacttgggtggagcactggcctgaggagga cgaatgccaagacgaagagaaccagaaacaatgccaggacctcggcgccttcaccgagagcatggttgtctttgggtgcc ccaactgaccacacccccattcc (SEQ ID NO: 12036) cgtgttgatgatggagtagcttcctttgtgcttaatctcccatctggagtgacggtgctggagtttaatgtcaaaactga tgctccagatcttccagaagaaaatcaggccagggaaggttaccgagcaatagcatactcatctctcagccaaagttacc tttatattgattggactgataaccataaggctttgctagtgggagaacatctgaatattattgttacccccaaaagccca tatattgacaaaataactcactataattacttgattttatccaagggcaaaattatccactttggcacgagggagaaatt ttcagatgcatcttatcaaagtataaacattccagtaacacagaacatggttccttcatcccgacttctggtctattata tcgtcacaggagaacagacagcagaattagtgtctgattcagtctggttaaatattgaagaaaaatgtggcaaccagctc caggttcatctgtctcctgatgcagatgcatattctccaggccaaactgtgtctcttaatatggcaactggaatggattc ctgggtggcattagcagcagtggacagtgctgtgtatggagtccaaagaggagccaaaaagcccttggaaagagtatttc aattcttagagaagagtgatctgggctgtggggcaggtggtggcctcaacaatgccaatgtgttccacctagctggactt accttcctcactaatgcaaatgcagatgactcccaagaaaatgatgaaccttgtaaagaaattctcaggccaagaagaac gctgcaaaagaagatagaagaaatagctgctaaatataaacattcagtagtgaagaaatgttgttacgatggagcctgcg ttaataatgatgaaacctgtgagcagcgagctgcacggattagtttagggccaagatgcatcaaagctttcactgaatgt tgtgtcgtcgcaagccagctccgtgctaatatctctcataaagacatgcaattgggaaggctacacatgaagaccctgtt accagtaagcaagccagaaattcggagttattttccagaaagctggttgtgggaagttcatcttgttcccagaagaaaac agttgcagtttgccctacctgattctctaaccacctgggaaattcaaggcattggcatttcaaacactggtatatgtgtt gctgatactgtcaaggcaaaggtgttcaaagatgtcttcctggaaatgaatataccatattctgttgtacgaggagaaca gatccaattgaaaggaactgtttacaactataggacttctgggatgcagttctgtgttaaaatgtctgctgtggagggaa tctgcacttcggaaagcccagtcattgatcatcagggcacaaagtcctccaaatgtgtgcgccagaaagtagagggctcc tccagtcacttggtgacattcactgtgcttcctctggaaattggccttcacaacatcaatttttcactggagacttggtt tggaaaagaaatcttagtaaaaacattacgagtggtgccagaaggtgtcaaaagggaaagctattctggtgttactttgg atcctaggggtatttatggtaccattagcagacgaaaggagttcccatacaggatacccttagatttggtccccaaaaca gaaatcaaaaggattttgagtgtaaaaggactgcttgtaggtgagatcttgtctgcagttctaagtcaggaaggcatcaa tatcctaacccacctccccaaagggagtgcagaggcggagctgatgagcgttgtcccagtattctatgtttttcactacc tggaaacaggaaatcattggaacatttttcattctgacccattaattgaaaagcagaaactgaagaaaaaattaaaagaa gggatgttgagcattatgtcctacagaaatgctgactactcttacagtgtgtggaagggtggaagtgctagcacttggtt aacagcttttgctttaagagtacttggacaagtaaataaatacgtagagcagaaccaaaattcaatttgtaattctttat tgtggctagttgagaattatcaattagataatggatctttcaaggaaaattcacagtatcaaccaataaaattacagggt accttgcctgttgaagcccgagagaacagcttatatcttacagcctttactgtgattggaattagaaaggctttcgatat atgccccctggtgaaaatcgacacagctctaattaaagctgacaactttctgcttgaaaatacactgccagcccagagca cctttacattggccatttctgcgtatgctctttccctgggagataaaactcacccacagtttcgttcaattgtttcagct ttgaagagagaagctttggttaaaggtaatccacccatttatcgtttttggaaagacaatcttcagcataaagacagctc tgtacctaacactggtacggcacgtatggtagaaacaactgcctatgctttactcaccagtctgaacttgaaagatataa attatgttaacccag catcaaatggctatcagaagagcagaggtatggaggtggcttttattcaacccaggacacaatc aatgccattgagggcctgacggaatattcactcctggttaaacaactccgcttgagtatggacatcgatgtttcttacaa gcataaaggtgccttacataattataaaatgacagacaagaatttccttgggaggccagtagaggtgcttctcaatgatg acctcattgtcagtacaggatttggcagtggcttggctacagtacatgtaacaactgtagttcacaaaaccagtacctct gaggaagtttgcagcttttatttgaaaatcgatactcaggatattgaagcatcccactacagaggctacggaaactctga ttacaaacgcatagtagcatgtgccagctacaagcccagcagggaagaatcatcatctggatcctctcatgcggtgatgg acatctccttgcctactggaatcagtgcaaatgaagaagacttaaaagcccttgtggaaggggtggatcaactattcact gattaccaaatcaaagatggacatgttattctgcaactgaattcgattccctccagtgatttcctttgtgtacgattccg gatatttgaactctttgaagttgggtttctcagtcctgccactttcacagtgtacgaataccacagaccagataaacagt gtaccatgttttatagcacttccaatatcaaaattcagaaagtctgtgaaggagccgcgtgcaagtgtgtagaagctgat tgtgggcaaatgcaggaagaattggatctgacaatctctgcagagacaagaaaacaaacagcatgtaaaccagagattgc atatgcttataaagttagcatcacatccatcactgtagaaaatgtttttgtcaagtacaaggcaacccttctggatatct acaaaactggggaagctgttgctgagaaagactctgagattaccttcattaaaaaggtaacctgtactaacgctgagctg gtaaaaggaagacagtacttaattatgggtaaagaagccctccagataaaatacaatttcagtttcaggtacatctaccc tttagattccttgacctggattgaatactggcctagagacacaacatgttcatcgtgtcaagcatttttagctaatttag atgaatttgccgaagatatctttttaaatggatgctaaaattcctgaagttcagctgcatacagtttgcacttatggact cctgttgttgaagttcgtttttttgttttcttctttttttaaacattcatagctggtcttatttgtaaagctcactttac ttagaattagtggcacttgcttttattagagaatgatttcaaatgctgtaactttctgaaataacatggccttggagggc atgaagacagatactcctccaaggttattggacaccggaaacaataaattggaacacctcctcaaacctaccactcagga atgtttgctggggccgaaagaacagtccattgaaagggagtattacaaaaacatggcctttgcttgaaagaaaataccaa ggaacaggaaactgatcattaaagcctgagtttgctttc (SEQ ID NO: 12037) ctacctccaaccatgggccttttgggaatactttgttttttaatcttcctggggaaaacctggggacaggagcaaacata tgtcatttcagcaccaaaaatattccgtgttggagcatctgaaaatattgtgattcaagtttatggatacactgaagcat ttgatgcaacaatctctattaaaagttatcctgataaaaaatttagttactcctcaggccatgttcatttatcctcagag aataaattccaaaactctgcaatcttaacaatacaaccaaaacaattgcctggaggacaaaacccagtttcttatgtgta tttggaagttgtatcaaagcatttttcaaaatcaaaaagaatgccaataacctatgacaatggatttctcttcattcata cagacaaacctgtttatactccagaccagtcagtaaaagttagagtttattcgttgaatgacgacttgaagccagccaaa agagaaactgtcttaaccttcatagatcctgaaggatcagaagttgacatggtagaagaaattgatcatattggaattat ctcttttcctgacttcaagattccgtctaatcctagatatggtatgtggacgatcaaggctaaatataaagaggactttt caacaactggaaccgcatattttgaagttaaagaatatgtcttgccacatttttctgtctcaatcgagccagaatataat ttcattggttacaagaactttaagaattttgaaattactataaaagcaagatatttttataataaagtagtcactgaggc tgacgtttatatcacatttggaataagagaagacttaaaagatgatcaaaaagaaatgatgcaaacagcaatgcaaaaca caatgttgataaatggaattgctcaagtcacatttgattctgaaacagcagtcaaagaactgtcatactacagtttagaa gatttaaacaacaagtacctttatattgctgtaacagtcatagagtctacaggtggattttctgaagaggcagaaatacc tggcatcaaatatgtcctctctccctacaaactgaatttggttgctactcctcttttcctgaagcctgggattccatatc ccatcaaggtgcaggttaaagattcgcttgaccagttggtaggaggagtcccagtaatactgaatgcacaaacaattgat gtaaaccaagagacatctgacttggatccaagcaaaagtgtaacacgtgttgatgatggagtagcttcctttgtgcttaa tctcccatctggagtgacggtgctggagtttaatgtcaaaactgatgctccagatcttccagaagaaaatcaggccaggg aaggttaccgagcaatagcatactcatctctcagccaaagttacctttatattgattggactgataaccataaggctttg ctagtgggagaacatctgaatattattgttacccccaaaagcccatatattgacaaaataactcactataattacttgat tttatccaagggcaaaattatccattttggcacgagggagaaattttcagatgcatcttatcaaagtataaacattccag taacacagaacatggttccttcatcccgacttctggtctattatatcgtcacaggagaacagacagcagaattagtgtct gattcagtctggttaaatattgaagaaaaatgtggcaaccagctccaggttcatctgtctcctgatgcagatgcatattc tccaggccaaactgtgtctcttaatatggcaactggaatggattcctgggtggcattagcagcagtggacagtgctgtgt atggagtccaaagaggagccaaaaagcccttggaaagagtatttcaattcttagagaagagtgatctgggctgtggggca ggtggtggcctcaacaatgccaatgtgttccacctagctggacttaccttcctcactaatgcaaatgcagatgactccca agaaaatgatgaaccttgtaaagaaattctcaggccaagaagaacgctgcaaaagaagatagaagaaatagctgctaaat ataaacattcagtagtgaagaaatgttgttacgatggagcctgcgttaataatgatgaaacctgtgagcagcgagctgca cggattagtttagggccaagatgcatcaaagctttcactgaatgttgtgtcgtcgcaagccagctccgtgctaatatctc tcataaagacatgcaattgggaaggctacacatgaagaccctgttaccagtaagcaagccagaaattcggagttattttc cagaaagctggttgtgggaagttcatcttgttcccagaagaaaacagttgcagtttgccctacctgattctctaaccacc tgggaaattcaaggcattggcatttcaaacactggtatatgtgttgctgatactgtcaaggcaaaggtgttcaaagatgt cttcctggaaatgaatataccatattctgttgtacgaggagaacagatccaattgaaaggaactgtttacaactatagga cttctgggatgcagttctgtgttaaaatgtctgctgtggagggaatctgcacttcggaaagcccagtcattgatcatcag ggcacaaagtcctccaaatgtgtgcgccagaaagtagagggctcctccagtcacttggtgacattcactgtgcttcctct ggaaattggccttcacaacatcaatttttcactggagacttggtttggaaaagaaatcttagtaaaaacattacgagtgg tgccagaaggtgtcaaaagggaaagctattctggtgttactttggatcctaggggtatttatggtaccattagcagacga aaggagttcccatacaggatacccttagatttggtccccaaaacagaaatcaaaaggattttgagtgtaaaaggactgct tgtaggtgagatcttgtctgcagttctaagtcaggaaggcatcaatatcctaacccacctccccaaagggagtgcagagg cggagctgatgagcgttgtcccagtattctatgtttttcactacctggaaacaggaaatcattggaacatttttcattct gacccattaattgaaaagcagaaactgaagaaaaaattaaaagaagggatgttgagcattatgtcctacagaaatgctga ctactcttacagtgtgtggaagggtggaagtgctagcacttggttaacagcttttgctttaagagtacttggacaagtaa ataaatacgtagagcagaaccaaaattcaatttgtaattctttattgtggctagttgagaattatcaattagataatgga tctttcaaggaaaattcacagtatcaaccaataaaattacagggtaccttgcctgttgaagcccgagagaacagcttata tcttacagcctttactgtgattggaattagaaaggctttcgatatatgccccctggtgaaaatcgacacagctctaatta aagctgacaactttctgcttgaaaatacactgccagcccagagcacctttacattggccatttctgcgtatgctctttcc ctgggagataaaactcacccacagtttcgttcaattgtttcagctttgaagagagaagctttggttaaaggtaatccacc catttatcgtttttggaaagacaatcttcagcataaagacagctctgtacctaacactggtacggcacgtatggtagaaa caactgcctatgctttactcaccagtctgaacttgaaagatataaattatgttaacccagtcatcaaatggctatcagaa gagcagaggtatggaggtggcttttattcaacccaggacaccatcaatgccattgagggcctgacggaatattcactcct ggttaaacaactccgcttgagtatggacatcgatgtttcttacaagcataaaggtgccttacataattataaaatgacag acaagaatttccttgggaggccagtagaggtgcttctcaatgatgacctcattgtcagtacaggatttggcagtggcttg gctacagtacatgtaacaactgtagttcacaaaaccagtacctctgaggaagtttgcagcttttatttgaaaatcgatac tcaggatattgaagcatcccactacagaggctacggaaactctgattacaaacgcatagtagcatgtgccagctacaagc ccagcagggaagaatcatcatctggatcctctcatgcggtgatggacatctccttgcctactggaatcagtgcaaatgaa gaagacttaaaagcccttgtggaaggggtggatcaactattcactgattaccaaatcaaagatggacatgttattctgca actgaattcgattccctccagtgatttcctttgtgtacgattccggatatttgaactctttgaagttgggtttctcagtc ctgccactttcacagtttacgaataccacagaccagataaacagtgtaccatgttttatagcacttccaatatcaaaatt cagaaagtctgtgaaggagccgcgtgcaagtgtgtagaagctgattgtgggcaaatgcaggaagaattggatctgacaat ctctgcagagacaagaaaacaaacagcatgtaaaccagagattgcatatgcttataaagttagcatcacatccatcactg tagaaaatgtttttgtcaagtacaaggcaacccttctggatatctacaaaactggggaagctgttgctgagaaagactct gagattaccttcattaaaaaggtaacctgtactaacgctgagctggtaaaaggaagacagtacttaattatgggtaaaga agccctccagataaaatacaatttcagtttcaggtacatctaccctttagattccttgacctggattgaatactggccta gagacacaacatgttcatcgtgtcaagcatttttagctaatttagatgaatttgccgaagatatctttttaaatggatgc taaaattcctgaagttcagctgcatacagtttgcacttatggactcctgttgttgaagttcgtttttttgttttcttctt tttttaaacattcatagctggtcttatttgtaaagctcactttacttagaattagtggcacttgcttttattagagaatg atttcaaatgctgtaactttctgaaataacatggccttggagggcatgaagacagatactcctccaaggttattggacac cggaaacaataaattggaacacctcctcaaacctaccactcaggaatgtttgctggggccgaaagaacagtccattgaaa gggagtattacaaaaacatggcctttgcttgaaagaaaataccaaggaacaggaaactgatcattaaagcctgagtttgc tttc (SEQ ID Nθ:12038) ctacctccaaccatgggccttttgggaatactttgttttttaatcttcctggggaaaacctggggacaggagcaaacata tgtcatttcagcaccaaaaatattccgtgttggagcatctgaaaatattgtgattcaagtttatggatacactgaagcat ttgatgcaacaatctctattaaaagttatcctgataaaaaatttagttactcctcaggccatgttcatttatcctcagag aataaattccaaaactctgcaatcttaacaatacaaccaaaacaattgcctggaggacaaaacccagtttcttatgtgta tttggaagttgtatcaaagcatttttcaaaatcaaaaagaatgccaataacctatgacaatggatttctcttcattcata cagacaaacctgtttatactccagaccagtcagtaaaagttagagtttattcgttgaatgacgacttgaagccagccaaa agagaaactgtcttaaccttcatagatcctgaaggatcagaagttgacatggtagaagaaattgatcatattggaattat ctcttttcctgacttcaagattccgtctaatcctagatatggtatgtggacgatcaaggctaaatataaagaggactttt caacaactggaaccgcatattttgaagttaaagaatatgtcttgccacatttttctgtctcaatcgagccagaatataat ttcattggttacaagaactttaagaattttgaaattactataaaagcaagatatttttataataaagtagtcactgaggc tgacgtttatatcacatttggaataagagaagacttaaaagatgatcaaaaagaaatgatgcaaacagcaatgcaaaaca caatgttgataaatggaattgctcaagtcacatttgattctgaaacagcagtcaaagaactgtcatactacagtttagaa gatttaaacaacaagtacctttatattgctgtaacagtcatagagtctacaggtggattttctgaagaggcagaaatacc tggcatcaaatatgtcctctctccctacaaactgaatttggttgctactcctcttttcctgaagcctgggattccatatc ccatcaaggtgcaggttaaagattcgcttgaccagttggtaggaggagtcccagtaatactgaatgcacaaacaattgat gtaaaccaagagacatctgacttggatccaagcaaaagtgtaacacgtgttgatgatggagtagcttcctttgtgcttaa tctcccatctggagtgacggtgctggagtttaatgtcaaaactgatgctccagatcttccagaagaaaatcaggccaggg aaggttaccgagcaatagcatactcatctctcagccaaagttacctttatattgattggactgataaccataaggctttg ctagtgggagaacatctgaatattattgttacccccaaaagcccatatattgacaaaataactcactataattacttgat tttatccaagggcaaaattatccattttggcacgagggagaaattttcagatgcatcttatcaaagtataaacattccag taacacagaacatggttccttcatcccgacttctggtctattatatcgtcacaggagaacagacagcagaattagtgtct gattcagtctggttaaatattgaagaaaaatgtggcaaccagctccaggttcatctgtctcctgatgcagatgcatattc tccaggccaaactgtgtctcttaatatggcaactggaatggattcctgggtggcattagcagcagtggacagtgctgtgt atggagtccaaagaggagccaaaaagcccttggaaagagtatttcaattcttagagaagagtgatctgggctgtggggca ggtggtggcctcaacaatgccaatgtgttccacctagctggacttaccttcctcactaatgcaaatgcagatgactccca agaaaatgatgaaccttgtaaagaaattctcaggccaagaagaacgctgcaaaagaagatagaagaaatagctgctaaat ataaacattcagtagtgaagaaatgttgttacgatggagcctgcgttaataatgatgaaacctgtgagcagcgagctgca cggattagtttagggccaagatgcatcaaagctttcactgaatgttgtgtcgtcgcaagccagctccgtgctaatatctc tcataaagacatgcaattgggaaggctacacatgaagaccctgttaccagtaagcaagccagaaattcggagttattttc cagaaagctggttgtgggaagttcatcttgttcccagaagaaaacagttgcagtttgccctacctgattctctaaccacc tgggaaattcaaggcattggcatttcaaacactggtatatgtgttgctgatactgtcaaggcaaaggtgttcaaagatgt cttcctggaaatgaatataccatattctgttgtacgaggagaacagatccaattgaaaggaactgtttacaactatagga cttctgggatgcagttctgtgttaaaatgtctgctgtggagggaatctgcacttcggaaagcccagtcattgatcatcag ggcacaaagtcctccaaatgtgtgcgccagaaagtagagggctcctccagtcacttggtgacattcactgtgcttcctct ggaaattggccttcacaacatcaatttttcactggagacttggtttggaaaagaaatcttagtaaaaacattacgagtgg tgccagaaggtgtcaaaagggaaagctattctggtgttactttggatcctaggggtatttatggtaccattagcagacga aaggagttcccatacaggatacccttagatttggtccccaaaacagaaatcaaaaggattttgagtgtaaaaggactgct tgtaggtgagatcttgtctgcagttctaagtcaggaaggcatcaatatcctaacccacctccccaaagggagtgcagagg cggagctgatgagcgttgtcccagtattctatgtttttcactacctggaaacaggaaatcattggaacatttttcattct gacccattaattgaaaagcagaaactgaagaaaaaattaaaagaagggatgttgagcattatgtcctacagaaatgctga ctactcttacagtgtgtggaagggtggaagtgctagcacttggttaacagcttttgctttaagagtacttggacaagtaa ataaatacgtagagcagaaccaaaattcaatttgtaattctttattgtggctagttgagaattatcaattagataatgga tctttcaaggaaaattcacagtatcaaccaataaaattacagggtaccttgcctgttgaagcccgagagaacagcttata tcttacagcctttactgtgattggaattagaaaggctttcgatatatgccccctggtgaaaatcgacacagctctaatta aagctgacaactttctgcttgaaaatacactgccagcccagagcacctttacattggccatttctgcgtatgctctttcc ctgggagataaaactcacccacagtttcgttcaattgtttcagctttgaagagagaagctttggttaaaggtaatccacc catttatcgtttttggaaagacaatcttcagcataaagacagctctgtacctaacactggtacggcacgtatggtagaaa caactgcctatgctttactcaccagtctgaacttgaaagatataaattatgttaacccagtcatcaaatggctatcagaa gagcagaggtatggaggtggcttttattcaacccaggacaccatcaatgccattgagggcctgacggaatattcactcct ggttaaacaactccgcttgagtatggacatcgatgtttcttacaagcataaaggtgccttacataattataaaatgacag acaagaatttccttgggaggccagtagaggtgcttctcaatgatgacctcattgtcagtacaggatttggcagtggcttg gctacagtacatgtaacaactgtagttcacaaaaccagtacctctgaggaagtttgcagcttttatttgaaaatcgatac tcaggatattgaagcatcccactacagaggctacggaaactctgattacaaacgcatagtagcatgtgccagctacaagc ccagcagggaagaatcatcatctggatcctctcatgcggtgatggacatctccttgcctactggaatcagtgcaaatgaa gaagacttaaaagcccttgtggaaggggtggatcaactattcactgattaccaaatcaaagatggacatgttattctgca actgaattcgattccctccagtgatttcctttgtgtacgattccggatatttgaactctttgaagttgggtttctcagtc ctgccactttcacagtttacgaataccacagaccagataaacagtgtaccatgttttatagcacttccaatatcaaaatt cagaaagtctgtgaaggagccgcgtgcaagtgtgtagaagctgattgtgggcaaatgcaggaagaattggatctgacaat ctctgcagagacaagaaaacaaacagcatgtaaaccagagattgcatatgcttataaagttagcatcacatccatcactg tagaaaatgtttttgtcaagtacaaggcaacccttctggatatctacaaaactggggaagctgttgctgagaaagactct gagattaccttcattaaaaaggtaacctgtactaacgctgagctggtaaaaggaagacagtacttaattatgggtaaaga agccctccagataaaatacaatttcagtttcaggtacatctaccctttagattccttgacctggattgaatactggccta gagacacaacatgttcatcgtgtcaagcatttttagctaatttagatgaatttgccgaagatatctttttaaatggatgc taaaattcctgaagttcagctgcatacagtttgcacttatggactcctgttgttgaagttcgtttttttgttttcttctt tttttaaacattcatagctggtcttatttgtaaagctcactttacttagaattagtggcacttgcttttattagagaatg atttcaaatgctgtaactttctgaaataacatggccttggagggcatgaagacagatactcctccaaggttattggacac cggaaacaataaattggaacacctcctcaaacctaccactcaggaatgtttgctggggccgaaagaacagtccattgaaa gggagtattacaaaaacatggcctttgcttgaaagaaaataccaaggaacaggaaactgatcattaaagcctgagtttgc tttc (SEQ ID NO: 12039) cgtgttgatgatggagtagcttcctttgtgcttaatctcccatctggagtgacggtgctggagtttaatgtcaaaactga tgctccagatcttccagaagaaaatcaggccagggaaggttaccgagcaatagcatactcatctctcagccaaagttacc tttatattgattggactgataaccataaggctttgctagtgggagaacatctgaatattattgttacccccaaaagccca tatattgacaaaataactcactataattacttgattttatccaagggcaaaattatccactttggcacgagggagaaatt ttcagatgcatcttatcaaagtataaacattccagtaacacagaacatggttccttcatcccgacttctggtctattata tcgtcacaggagaacagacagcagaattagtgtctgattcagtctggttaaatattgaagaaaaatgtggcaaccagctc caggttcatctgtctcctgatgcagatgcatattctccaggccaaactgtgtctcttaatatggcaactggaatggattc ctgggtggcattagcagcagtggacagtgctgtgtatggagtccaaagaggagccaaaaagcccttggaaagagtatttc aattcttagagaagagtgatctgggctgtggggcaggtggtggcctcaacaatgccaatgtgttccacctagctggactt accttcctcactaatgcaaatgcagatgactcccaagaaaatgatgaaccttgtaaagaaattctcaggccaagaagaac gctgcaaaagaagatagaagaaatagctgctaaatataaacattcagtagtgaagaaatgttgttacgatggagcctgcg ttaataatgatgaaacctgtgagcagcgagctgcacggattagtttagggccaagatgcatcaaagctttcactgaatgt tgtgtcgtcgcaagccagctccgtgctaatatctctcataaagacatgcaattgggaaggctacacatgaagaccctgtt accagtaagcaagccagaaattcggagttattttccagaaagctggttgtgggaagttcatcttgttcccagaagaaaac agttgcagtttgccctacctgattctctaaccacctgggaaattcaaggcattggcatttcaaacactggtatatgtgtt gctgatactgtcaaggcaaaggtgttcaaagatgtcttcctggaaatgaatataccatattctgttgtacgaggagaaca gatccaattgaaaggaactgtttacaactataggacttctgggatgcagttctgtgttaaaatgtctgctgtggagggaa tctgcacttcggaaagcccagtcattgatcatcagggcacaaagtcctccaaatgtgtgcgccagaaagtagagggctcc tccagtcacttggtgacattcactgtgcttcctctggaaattggccttcacaacatcaatttttcactggagacttggtt tggaaaagaaatcttagtaaaaacattacgagtggtgccagaaggtgtcaaaagggaaagctattctggtgttactttgg atcctaggggtatttatggtaccattagcagacgaaaggagttcccatacaggatacccttagatttggtccccaaaaca gaaatcaaaaggattttgagtgtaaaaggactgcttgtaggtgagatcttgtctgcagttctaagtcaggaaggcatcaa tatcctaacccacctccccaaagggagtgcagaggcggagctgatgagcgttgtcccagtattctatgtttttcactacc tggaaacaggaaatcattggaacatttttcattctgacccattaattgaaaagcagaaactgaagaaaaaattaaaagaa gggatgttgagcattatgtcctacagaaatgctgactactcttacagtgtgtggaagggtggaagtgctagcacttggtt aacagcttttgctttaagagtacttggacaagtaaataaatacgtagagcagaaccaaaattcaatttgtaattctttat tgtggctagttgagaattatcaattagataatggatctttcaaggaaaattcacagtatcaaccaataaaattacagggt accttgcctgttgaagcccgagagaacagcttatatcttacagcctttactgtgattggaattagaaaggctttcgatat atgccccctggtgaaaatcgacacagctctaattaaagctgacaactttctgcttgaaaatacactgccagcccagagca cctttacattggccatttctgcgtatgctctttccctgggagataaaactcacccacagtttcgttcaattgtttcagct ttgaagagagaagctttggttaaaggtaatccacccatttatcgtttttggaaagacaatcttcagcataaagacagctc tgtacctaacactggtacggcacgtatggtagaaacaactgcctatgctttactcaccagtctgaacttgaaagatataa attatgttaacccagtcatcaaatggctatcagaagagcagaggtatggaggtggcttttattcaacccaggacacaatc aatgccattgagggcctgacggaatattcactcctggttaaacaactccgcttgagtatggacatcgatgtttcttacaa gcataaaggtgccttacataattataaaatgacagacaagaatttccttgggaggccagtagaggtgct ctcaatgatg acctcattgtcagtacaggatttggcagtggcttggctacagtacatgtaacaactgtagttcacaaaaccagtacctct gaggaagtttgcagcttttatttgaaaatcgatactcaggatattgaagcatcccactacagaggctacggaaactctga ttacaaacgcatagtagcatgtgccagctacaagcccagcagggaagaatcatcatctggatcctctcatgcggtgatgg acatctccttgcctactggaatcagtgcaaatgaagaagacttaaaagcccttgtggaaggggtggatcaactattcact gattaccaaatcaaagatggacatgttattctgcaactgaattcgattccctccagtgatttcctttgtgtacgattccg gatatttgaactctttgaagttgggtttctcagtcctgccactttcacagtgtacgaataccacagaccagataaacagt gtaccatgttttatagcacttccaatatcaaaattcagaaagtctgtgaaggagccgcgtgcaagtgtgtagaagctgat tgtgggcaaatgcaggaagaattggatctgacaatctctgcagagacaagaaaacaaacagcatgtaaaccagagattgc atatgcttataaagttagcatcacatccatcactgtagaaaatgtttttgtcaagtacaaggcaacccttctggatatct acaaaactggggaagctgttgctgagaaagactctgagattaccttcattaaaaaggtaacctgtactaacgctgagctg gtaaaaggaagacagtacttaattatgggtaaagaagccctccagataaaatacaatttcagtttcaggtacatctaccc tttagattccttgacctggattgaatactggcctagagacacaacatgttcatcgtgtcaagcatttttagctaatttag atgaatttgccgaagata ctttttaaatggatgctaaaattcctgaagttcagctgcatacagtttgcacttatggact cctgttgttgaagttcgtttttttgttttcttctttttttaaacattcatagctggtcttatttgtaaagctcactttac ttagaattagtggcacttgcttttattagagaatgatttcaaatgctgtaactttctgaaataacatggccttggagggc atgaagacagatactcctccaaggttattggacaccggaaacaataaattggaacacctcctcaaacctaccactcagga atgtttgctggggccgaaagaacagtccattgaaagggagtattacaaaaacatggcctttgcttgaaagaaaataccaa ggaacaggaaactgatcattaaagcctgagtttgctttcctacctccaaccatgggccttttgggaatactttgtttttt aatcttcctggggaaaacctggggacaggagcaaacatatgtcatttcagcaccaaaaatattccgtgttggagcatctg aaaatattgtgattcaagtttatggatacactgaagcatttgatgcaacaatctctattaaaagttatcctgataaaaaa tttagttactcctcaggccatgttcatttatcctcagagaataaattccaaaactctgcaatcttaacaatacaaccaaa acaattgcctggaggacaaaacccagtttcttatgtgtatttggaagttgtatcaaagcatttttcaaaatcaaaaagaa tgccaataacctatgacaatggatttctcttcattcatacagacaaacctgtttatactccagaccagtcagtaaaagtt agagtttattcgttgaatgacgacttgaagccagccaaaagagaaactgtcttaaccttcatagatcctgaaggatcaga agttgacatggtagaagaaattgatcatattggaattatctcttttcctgacttcaagattccgtctaatcctagatatg gtatgtggacgatcaaggctaaatataaagaggacttttcaacaactggaaccgcatattttgaagttaaagaatatgtc ttgccacatttttctgtctcaatcgagccagaatataatttcattggttacaagaactttaagaattttgaaattactat aaaagcaagatatttttataataaagtagtcactgaggctgacgtttatatcacatttggaataagagaagacttaaaag atgatcaaaaagaaatgatgcaaacagcaatgcaaaacacaatgttgataaatggaattgctcaagtcacatttgattct gaaacagcagtcaaagaactgtcatactacagtttagaagatttaaacaacaagtacctttatattgctgtaacagtcat agagtctacaggtggattttctgaagaggcagaaatacctggcatcaaatatgtcctctctccctacaaactgaatttgg ttgctactcctcttttcctgaagcctgggattccatatcccatcaaggtgcaggttaaagattcgcttgaccagttggta ggaggagtcccagtaatactgaatgcacaaacaattgatgtaaaccaagagacatctgacttggatccaagcaaaagtgt aacacgtgttgatgatggagtagcttcctttgtgcttaatctcccatctggagtgacggtgctggagtttaatgtcaaaa ctgatgctccagatcttccagaagaaaatcaggccagggaaggttaccgagcaatagcatactcatctctcagccaaagt tacctttatattgattggactgataaccataaggctttgctagtgggagaacatctgaatattattgttacccccaaaag cccatatattgacaaaataactcactataattacttgattttatccaagggcaaaattatccattttggcacgagggaga aattttcagatgcatcttatcaaagtataaacattccagtaacacagaacatggttccttcatcccgacttctggtctat tatatcgtcacaggagaacagacagcagaattagtgtctgattcagtctggttaaatattgaagaaaaatgtggcaacca gctccaggttcatctgtctcctgatgcagatgcatattctccaggccaaactgtgtctcttaatatggcaactggaatgg attcctgggtggcattagcagcagtggacagtgctgtgtatggagtccaaagaggagccaaaaagcccttggaaagagta tttcaattcttagagaagagtgatctgggctgtggggcaggtggtggcctcaacaatgccaatgtgttccacctagctgg acttaccttcctcactaatgcaaatgcagatgactcccaagaaaatgatgaaccttgtaaagaaattctcaggccaagaa gaacgctgcaaaagaagatagaagaaatagctgctaaatataaacattcagtagtgaagaaatgttgttacgatggagcc tgcgttaataatgatgaaacctgtgagcagcgagctgcacggattagtttagggccaagatgcatcaaagctttcactga atgttgtgtcgtcgcaagccagctccgtgctaatatctctcataaagacatgcaattgggaaggctacacatgaagaccc tgttaccagtaagcaagccagaaattcggagttattttccagaaagctggttgtgggaagttcatcttgttcccagaaga aaacagttgcagtttgccctacctgattctctaaccacctgggaaattcaaggcattggcatttcaaacactggtatatg tgttgctgatactgtcaaggcaaaggtgttcaaagatgtcttcctggaaatgaatataccatattctgttgtacgaggag aacagatccaattgaaaggaactgtttacaactataggacttctgggatgcagttctgtgttaaaatgtctgctgtggag ggaatctgcacttcggaaagcccagtcattgatcatcagggcacaaagtcctccaaatgtgtgcgccagaaagtagaggg ctcctccagtcacttggtgacattcactgtgcttcctctggaaattggccttcacaacatcaatttttcactggagactt ggtttggaaaagaaatcttagtaaaaacattacgagtggtgccagaaggtgtcaaaagggaaagctattctggtgttact ttggatcctaggggtatttatggtaccattagcagacgaaaggagttcccatacaggatacccttagatttggtccccaa aacagaaatcaaaaggattttgagtgtaaaaggactgcttgtaggtgagatcttgtctgcagttctaagtcaggaaggca tcaatatcctaacccacctccccaaagggagtgcagaggcggagctgatgagcgttgtcccagtattctatgtttttcac tacctggaaacaggaaatcattggaacatttttcattctgacccattaattgaaaagcagaaactgaagaaaaaattaaa agaagggatgttgagcattatgtcctacagaaatgctgactactcttacagtgtgtggaagggtggaagtgctagcactt ggttaacagcttttgctttaagagtacttggacaagtaaataaatacgtagagcagaaccaaaattcaatttgtaattct ttattgtggctagttgagaattatcaattagataatggatctttcaaggaaaattcacagtatcaaccaataaaattaca gggtaccttgcctgttgaagcccgagagaacagcttatatcttacagcctttactgtgattggaattagaaaggctttcg atatatgccccctggtgaaaatcgacacagctctaattaaagctgacaactttctgcttgaaaatacactgccagcccag agcacctttacattggccatttctgcgtatgctctttccctgggagataaaactcacccacagtttcgttcaattgtttc agctttgaagagagaagctttggttaaaggtaatccacccatttatcgtttttggaaagacaatcttcagcataaagaca gctctgtacctaacactggtacggcacgtatggtagaaacaactgcctatgctttactcaccagtctgaacttgaaagat ataaattatgttaacccagtcatcaaatggctatcagaagagcagaggtatggaggtggcttttattcaacccaggacac catcaatgccattgagggcctgacggaatattcactcctggttaaacaactccgcttgagtatggacatcgatgtttctt acaagcataaaggtgccttacataattataaaatgacagacaagaatttccttgggaggccagtagaggtgcttctcaat gatgacctcattgtcagtacaggatttggcagtggcttggctacagtacatgtaacaactgtagttcacaaaaccagtac ctctgaggaagtttgcagcttttatttgaaaatcgatactcaggatattgaagcatcccactacagaggctacggaaact ctgattacaaacgcatagtagcatgtgccagctacaagcccagcagggaagaatcatcatctggatcctctcatgcggtg atggacatctccttgcctactggaatcagtgcaaatgaagaagacttaaaagcccttgtggaaggggtggatcaactatt cactgattaccaaatcaaagatggacatgttattctgcaactgaattcgattccctccagtgatttcctttgtgtacgat tccggatatttgaactctttgaagttgggtttctcagtcctgccactttcacagtttacgaataccacagaccagataaa cagtgtaccatgttttatagcacttccaatatcaaaattcagaaagtctgtgaaggagccgcgtgcaagtgtgtagaagc tgattgtgggcaaatgcaggaagaattggatctgacaatctctgcagagacaagaaaacaaacagcatgtaaaccagaga ttgcatatgcttataaagttagcatcacatccatcactgtagaaaatgtttttgtcaagtacaaggcaacccttctggat atctacaaaactggggaagctgttgctgagaaagactctgagattaccttcattaaaaaggtaacctgtactaacgctga gctggtaaaaggaagacagtacttaattatgggtaaagaagccctccagataaaatacaatttcagtttcaggtacatct accctttagattccttgacctggattgaatactggcctagagacacaacatgttcatcgtgtcaagcatttttagctaat ttagatgaatttgccgaagatatctttttaaatggatgctaaaattcctgaagttcagctgcatacagtttgcacttatg gactcctgttgttgaagttcgtttttttgttttcttctttttttaaacattcatagctggtcttatttgtaaagctcact ttacttagaattagtggcacttgcttttattagagaatgatttcaaatgctgtaactttctgaaataacatggccttgga gggcatgaagacagatactcctccaaggttattggacaccggaaacaataaattggaacacctcctcaaacctaccactc aggaatgtttgctggggccgaaagaacagtccattgaaagggagtattacaaaaacatggcctttgcttgaaagaaaata ccaaggaacaggaaactgatcattaaagcctgagtttgctttcctacctccaaccatgggccttttgggaatactttgtt ttttaatcttcctggggaaaacctggggacaggagcaaacatatgtcatttcagcaccaaaaatattccgtgttggagca tctgaaaatattgtgattcaagtttatggatacactgaagcatttgatgcaacaatctctattaaaagttatcctgataa aaaatttagttactcctcaggccatgttcatttatcctcagagaataaattccaaaactctgcaatcttaacaatacaac caaaacaattgcctggaggacaaaacccagtttcttatgtgtatttggaagttgtatcaaagcatttttcaaaatcaaaa agaatgccaataacctatgacaatggatttctcttcattcatacagacaaacctgtttatactccagaccagtcagtaaa agttagagtttattcgttgaatgacgacttgaagccagccaaaagagaaactgtcttaaccttcatagatcctgaaggat cagaagttgacatggtagaagaaattgatcatattggaattatctcttttcctgacttcaagattccgtctaatcctaga tatggtatgtggacgatcaaggctaaatataaagaggacttttcaacaactggaaccgcatattttgaagttaaagaata tgtcttgccacatttttctgtctcaatcgagccagaatataatttcattggttacaagaactttaagaattttgaaatta ctataaaagcaagatatttttataataaagtagtcactgaggctgacgtttatatcacatttggaataagagaagactta aaagatgatcaaaaagaaatgatgcaaacagcaatgcaaaacacaatgttgataaatggaattgctcaagtcacatttga ttctgaaacagcagtcaaagaactgtcatactacagtttagaagatttaaacaacaagtacctttatattgctgtaacag tcatagagtctacaggtggattttctgaagaggcagaaatacctggcatcaaatatgtcctctctccctacaaactgaat ttggttgctactcctcttttcctgaagcctgggattccatatcccatcaaggtgcaggttaaagattcgcttgaccagtt ggtaggaggagtcccagtaatactgaatgcacaaacaattgatgtaaaccaagagacatctgacttggatccaagcaaaa gtgtaacacgtgttgatgatggagtagcttcctttgtgcttaatctcccatctggagtgacggtgctggagtttaatgtc aaaactgatgctccagatcttccagaagaaaatcaggccagggaaggttaccgagcaatagcatactcatctctcagcca aagttacctttatattgattggactgataaccataaggctttgctagtgggagaacatctgaatattattgttaccccca aaagcccatatattgacaaaataactcactataattacttgattttatccaagggcaaaattatccattttggcacgagg gagaaattttcagatgcatcttatcaaagtataaacattccagtaacacagaacatggttccttcatcccgacttctggt ctattatatcgtcacaggagaacagacagcagaattagtgtctgattcagtctggttaaatattgaagaaaaatgtggca accagctccaggttcatctgtctcctgatgcagatgcatattctccaggccaaactgtgtctcttaatatggcaactgga atggattcctgggtggcattagcagcagtggacagtgctgtgtatggagtccaaagaggagccaaaaagcccttggaaag agtatttcaattcttagagaagagtgatctgggctgtggggcaggtggtggcctcaacaatgccaatgtgttccacctag ctggacttaccttcctcactaatgcaaatgcagatgactcccaagaaaatgatgaaccttgtaaagaaattctcaggcca agaagaacgctgcaaaagaagatagaagaaatagctgctaaatataaacattcagtagtgaagaaatgttgttacgatgg agcctgcgttaataatgatgaaacctgtgagcagcgagctgcacggattagtttagggccaagatgcatcaaagctttca ctgaatgttgtgtcgtcgcaagccagctccgtgctaatatctctcataaagacatgcaattgggaaggctacacatgaag accctgttaccagtaagcaagccagaaattcggagttattttccagaaagctggttgtgggaagttcatcttgttcccag aagaaaacagttgcagtttgccctacctgattctctaaccacctgggaaattcaaggcattggcatttcaaacactggta tatgtgttgctgatactgtcaaggcaaaggtgttcaaagatgtcttcctggaaatgaatataccatattctgttgtacga ggagaacagatccaattgaaaggaactgtttacaactataggacttctgggatgcagttctgtgttaaaatgtctgctgt ggagggaatctgcacttcggaaagcccagtcattgatcatcagggcacaaagtcctccaaatgtgtgcgccagaaagtag agggctcctccagtcacttggtgacattcactgtgcttcctctggaaattggccttcacaacatcaatttttcactggag acttggtttggaaaagaaatcttagtaaaaacattacgagtggtgccagaaggtgtcaaaagggaaagctattctggtgt tactttggatcctaggggtatttatggtaccattagcagacgaaaggagttcccatacaggatacccttagatttggtcc ccaaaacagaaatcaaaaggattttgagtgtaaaaggactgcttgtaggtgagatcttgtctgcagttctaagtcaggaa ggcatcaatatcctaacccacctccccaaagggagtgcagaggcggagctgatgagcgttgtcccagtattctatgtttt tcactacctggaaacaggaaatcattggaacatttttcattctgacccattaattgaaaagcagaaactgaagaaaaaat taaaagaagggatgttgagcattatgtcctacagaaatgctgactactcttacagtgtgtggaagggtggaagtgctagc acttggttaacagcttttgctttaagagtacttggacaagtaaataaatacgtagagcagaaccaaaattcaatttgtaa ttctttattgtggctagttgagaattatcaattagataatggatctttcaaggaaaattcacagtatcaaccaataaaat tacagggtaccttgcctgttgaagcccgagagaacagcttatatcttacagcctttactgtgattggaattagaaaggct ttcgatatatgccccctggtgaaaatcgacacagctctaattaaagctgacaactttctgcttgaaaatacactgccagc ccagagcacctttacattggccatttctgcgtatgctctttccctgggagataaaactcacccacagtttcgttcaattg tttcagctttgaagagagaagctttggttaaaggtaatccacccatttatcgtttttggaaagacaatcttcagcataaa gacagctctgtacctaacactggtacggcacgtatggtagaaacaactgcctatgctttactcaccagtctgaacttgaa agatataaattatgttaacccagtcatcaaatggctatcagaagagcagaggtatggaggtggcttttattcaacccagg acaccatcaatgccattgagggcctgacggaatattcactcctggttaaacaactccgcttgagtatggacatcgatgtt tcttacaagcataaaggtgccttacataattataaaatgacagacaagaatttccttgggaggccagtagaggtgcttct caatgatgacctcattgtcagtacaggatttggcagtggcttggctacagtacatgtaacaactgtagttcacaaaacca gtacctctgaggaagtttgcagcttttatttgaaaatcgatactcaggatattgaagcatcccactacagaggctacgga aactctgattacaaacgcatagtagcatgtgccagctacaagcccagcagggaagaatcatcatctggatcctctcatgc ggtgatggacatctccttgcctactggaatcagtgcaaatgaagaagacttaaaagcccttgtggaaggggtggatcaac tattcactgattaccaaatcaaagatggacatgttattctgcaactgaattcgattccctccagtgatttcctttgtgta cgattccggatatttgaactctttgaagttgggtttctcagtcctgccactttcacagtttacgaataccacagaccaga taaacagtgtaccatgttttatagcacttccaatatcaaaattcagaaagtctgtgaaggagccgcgtgcaagtgtgtag aagctgattgtgggcaaatgcaggaagaattggatctgacaatctctgcagagacaagaaaacaaacagcatgtaaacca gagattgcatatgcttataaagttagcatcacatccatcactgtagaaaatgtttttgtcaagtacaaggcaacccttct ggatatctacaaaactggggaagctgttgctgagaaagactctgagattaccttcattaaaaaggtaacctgtactaacg ctgagctggtaaaaggaagacagtacttaattatgggtaaagaagccctccagataaaatacaatttcagtttcaggtac atctaccctttagattccttgacctggattgaatactggcctagagacacaacatgttcatcgtgtcaagcatttttagc taatttagatgaatttgccgaagatatctttttaaatggatgctaaaattcctgaagttcagctgcatacagtttgcact tatggactcctgttgttgaagttcgtttttttgttttcttctttttttaaacattcatagctggtcttatttgtaaagct cactttacttagaattagtggcacttgcttttattagagaatgatttcaaatgctgtaactttctgaaataacatggcct tggagggcatgaagacagatactcctccaaggttattggacaccggaaacaataaattggaacacctcctcaaacctacc actcaggaatgtttgctggggccgaaagaacagtccattgaaagggagtattacaaaaacatggcctttgcttgaaagaa aataccaaggaacaggaaactgatcattaaagcctgagtttgctttc (SEQ ID NO: 12040) aagcttcagtatgcaaattttcaatgacatgtgcctgtggattctgaaaattcacagatctgtctatccttagctgagac tgaaggcatctacttcccaatgaccaaatcctggtgctgtggcgacactgagcaggaactccattagaatatcaatatca ctctgcagacattccatgatgtaagctatgttttctcttgttgcaattacacttaatttaccaccagctgcttcaatgtc atgggctatcttgaaaaatgaagctcctttcgtagtcaaactggatgcaagacacagcaaatgagaagttactaaattgt tggagtcctcatagctactgcctgctttaatgaacaaaccaattcttgatgcagggcatagttttccaaaggagaaatca taaaaccatttggaaatttgatgatctcaaggtcctgatgatgtggagccactcctatgggggtagctgtggctttaact ttgggggcaactttgagggaataaagtctcaaaaagagggaataaagtctcaagattgttcgtgacccatagtaacttct ggcttaaaggaccattcggcaagtttttaaatgtattttctataatttccatgtagttctttatattttctatttcttat ttaaaacctctattttagctcgtttcctttgacactgctctggcagggaaaggggtggcactgcctcattactgccaggt aggggtagaagtccattatccacttggtctccattgatacccaaagtggggagaggctcctgttactgctggtgagggtg ggagtccccccactaagtttctgctaatactgtcctggtggcttgctactattcccatgaagcctccactgatactacat tacttttgggtggtggcaaatgtcctgcctctccactagccctcctgctctaaaacaacccgagtagggagtgggaagga agctttgttactggtaggtgggagctgaagtccagacttgccacattgtcccactgatgctacagggaggaggaagcggg ccacattactgcctgatagggatgaaagccccagctccctacctggccttcgctgataccagcctgctacaggagtgaag agagatttgaaggcctcaatatagcctgtcgagggtggaagtcttgctcccaatgggcctttagcagcatgggtgggtgt ggggccatagctgtctctgtactgcttggctagagtggagtatttgaggtccaaaagttttctgtctttctagccctttg gttagaaagagcagacttttgttggaagtatttttttgtgtttacctgttgtatttccaggttcctagcttctccagcac agtctgggatgtgtgagacacagagaaaatccagtgatgttactaccgtatggtttcttgggtcccaacgtctctagcta atctgctccaccttttggagttttcttatttgttttagatcagggatttagtcatatttaataggagaaatatggaaaaa tacttctactctatcttcctggaagttcctgtttattttttatgtccttttcctctggctagaccgtaagagacttacga aacaaacacttacacattctactaaactcaatgtccaaagtttgtgaacttcttgaatattgcttgttcatttccacccc cagtcactgactgaatctccctgctgtctgtctacaatgccaatgagcttctggttaacttcttctcatgcatgcttagg caacaacttcccagttttactacacttgcccatccctagttttgttgttgcttaatcccttggcctagtgccaccatact cctccagcagagcaaccaattcttacattataggacagcacatatccactaaaaacagttcatgccacaccaaccacatt tccctttgtcaacaaaattacttgatagataattccaggaatgcctgatgaagctgattgacaacaagatatttggcaga ctctctgctgcctatacataccttagcatgtggaactcaagtaatgagaggtccatttaattggattgaattgggctgga taggattggattgaatcctgtgggatggctaggctaaattagaaatgaagactagtttaacagcagtatccaaggatagt tgactaatgagttaattttactctcaaagacagtctttagtagtaagctgtaatgcattatatcaaactattttccagtc aatgatttataagttacttgaataaggatgctaaagatgtgccttattgaaatggcaattagcacaaagttgggaatgaa a ctaattagttaaataacagaatcacataaaaaaggacttgaataaatgtagcatcctaccatgttcctggatagaaag actgctatcgtaaagatattcattctcctcaggttaaattataaactcaatgcaattcaacaggattttaaaaaactaga caaagtgattccaagtttacgtggaaaataaaatgtgagggaccaaacaatatttgaaaaagaaagagaataaaatctca tccttccagataccacaatgtattataaagcaatagtaattaacatgagggcagaaatgagcaagcaagtgaacaaaata agacagatagtcacaggaaactcatatatttataggtgctttgcgtataatgaagatggtccttcaaatcagttgggaaa agatgggttattcaataaatggtgttgggtaaaattggttatacattggtgagaaataaagtgaaactcctactttgtat catatgcaaaaaatagattccagacagatgaaatatttaaatgtaaaaaataaaattctaaaactactagaaaaaaaaga agaatatttttattcctttgaaatagaaaaggtcttactaagcaaaacacagaagtaataaatgaataaatgaagacaaa tatgataaaaataagttaaaaatataagcaatctttctttgtttttttttcacctttcctagaaaaaaatatataggcaa cttgttaagcaaggtagattacaagaaaatatttacaacatttgacaggccacagattattatccagcctcatctgataa gaaaacttcaacataaagatatctgttttttttcttataaggttcctcaaagtgagccaatcacttcttaagctgaacaa aaaacaaaacagaagtgatcttttccaataatgaaaacaaacattgacagagcagctgtaggatcctttcaggcaaatta tgaaaaggtgccctttctcagaaaccacagttaccattcagctttgtgaccagaggtttgactgtaccctagtccctact agcaacccaaccacataaccaacttcaaaggtcctgaatgactgtgttgtacttaatggcagatgatctatctcccattt ttgtcctaaggattttccaagataatatatttctgcatttgttttgcttttacttcactccaaattgaaatctatttgtg ggataagactaaagaaatgcttataggaaaattgatagcaccaaattcctatcttaaaaaatgaaaaaggtttcaaatca atgacctcagcttttactttaagaaaatagaaaaagcaggataagctaaagccaaagtaaacagaagaaaggaaattata aagataagagcagaaatcaatgaatagaaaacaaaagaaaaaaatcaaaccaaacagctgattctttaagcagatctata aaattgataaaactctagccagattgatcaagtaaaaaagagagaagacacaaattaccagtattaagaatgagagaggc aatatcactacagatcctacagatataaaaagtataagggcatactttgaataattttatgactataaattaggcaactt agataaaacaaatttcttgaaagacacaaacaaccaaagctcacctaaaatactcacaaattgaatagtcttatagctat tacaaaattgaggccaggcgcagtggctcaagcctttaatcccagcactttgggagggctaggaaggcggatcacgaggt caggagtttgagaccagcctgactaacatggtgaaaccctgtctctactaaaagtacaaaaattagccaggcttggtggt gcgtgcctgtaatcccatc actcaggagactgaggcaggagaattgcttgaacctgggaggcaaagttgtggtgagccg agatcgcgccactgcacttcagcctgggcaacagaacaagactccgtctcaaaaaaaaaaaaaaaaaaaaaaattgaaat tatagttaaaagtcttcccacaaagcaaactctagacccagatggcttcaatggtaaattctactggacaatcaaacagg aaacagtaataattctccacaatgtctttcataaaattgatgcggaggagatactctccaactcattctatgaaactagc attaccctgataccaaaatcatacagagacagtgtaggaaaacaacagatcagtatccttcatgaacataaatgaagtac aatgcagtcttatgcataaatcagagcttcattgttctacagataaggtaatgtaggattgttggttgcccctccaggtc tgttaaattcacctccttccccagagagcatccttcttaaggacagggagcctcaatatgtcagtcctcacagcacctcc ctcagtcttcagcacttaccagctcatcaccacaaccgataccacattggataatttcatgaattactttagagcaaatg caagagaaaaaatggatttttatataggagaagaaggaggaaattcttgtggatttggtacagaatagggccaagggaaa attacagatgtaaaaagaaaagtgtgtgaaatagtatccttagtgctcacaaatacaatgatttcattgtttttaaaaat aaaaaatgacaaatgtctaatgcttggtggtaatgctttattgaatgtgtgttatacactggttcctcattcctgaagtt agaaataataccttcctcttttcatttggttatgtttgctgaaacaaatcaaaggctgagattgaaacacatgctacttc aggtggatgaccttactactaagctcatcacaacagcacttacagctgaagaccccagagtcctacctaacttttgtcac aacccagattttggccatgtagttctgggccttaccattaaagcagacagaagtcagaggaatgactcctttccacttga agtgagctgcaggcttctaggaaaggcaagatgcacatttccctcctgtggagcataaagcctttgtaattcaggactta ggacccatatggatttgaaatattatgacattggagctggagtggttggggacaacaccagtagtgttataggccatgga atgtcaaaagaacatggaaccctgttaaaatcattaaacatcaaaactctcccctcctctggtgatatggtttggctgtg tccccatccaaatctcatcttgaactcccatgtgttgtgggaggcacccagtgggaggtaattgaatcatgggggcaggt ctttcccatgctgttttcacgatactgaataagtctcacaagatctgatggttttataaaggggagcttccctgcacaag ctctcttctcttgtctgccaccatgtgagacatgcctttcaccttccgccatgattgtgaggcctccccaaccatgtgga acttttaagttcattaaacctcttccttttgtaaattgctcagtctcaaatatgtctttatcagcaacgtgaaaacagac tatctgattttctgtgggatgtggattatgaccatggacagagcataactgggacagagctggaaaaaatattaattagg tgcttaaaaatatttgttagaactatcttcatgaatgagaatcaatcctgtttccatggtgattcaccaggcatcaattc caagcatccatgaatcagaaaagtcctatcttctcttagttatcatccaggactccaaggaaccataattagccaacctg ttcacatttccttttcattcactagcctcgaagtttccaggggacagggactctgtcctattcatttctgtaaccttacc acctgacccagaatagctgttccctgaagatttggtggattataaatgtggatgtcttatttctttgaaagtgtgagctt caggtactgatcacgttattccaattatcaatttagtatctttcttcaccattaaactgtgaaattcttgagggaagaac ctatgactgatttatctctgtaaactcatgccaccagtattcaaaatcacacctagcacatagtaaacactcaatgtttg ttgaatgactgaaggaatggatgaaaatgaacctccttgcttctgaccagtggatgagttgcttggccgtgttcctacag cctagagctcatcccctaaagcatctgaagttacccattagtgcaatggttcttgaacgctggtgttgatcagaatcatc tggatgcccaggttctctgaaataagatagggtctaggcatttgtatttttaccaaggaggtgtgatggagtcagatgca agaaggctagttgaagaaaccacatgagagtttagtgtagtgtattagaagactggtttggctctgtcgctagtggctac atcatcttgctcaagtcatgccagtctcaggacctcattcagtctcttcagctgtaatatgggtgggttgcaccacataa ccagaaagatcccttccagctctacccacttacaacatggtcaaatttggtctgattttttaaatcgtagtacaatatat atgacataaaattcaccattttagccactttaaatgtacaattctgtagcattaactacattcacattgttgtgcaacca tcactaccgtctacttccagaactcttcatcttgcaaaactgaacctctgttgtcattagtcactaactattcctctccc cccctccttctaggccctggcaatcaccattctactttctgtcgctatgaatttgactactctaggtaacttatataagt ggaatcacagcatttgccctattatgactggtttagttgacttagcacaacctcctaaggctcaaccacattttagcatg tgtcagaattttctttgtttttaaggctgaataatattctgttgtatctgtaaataacatctttattcatttgtccatca acagactgttgagttcctcccatcttttgactattgtgaaaaatgctgctatgaacctgagtgtacagacatctggttga gtactgctttcaattcattgtttatatggatcatatggtaattttatgtttaatttttttggaactgctacattgttttc cacagtgtacatcattttacatttccatcagcaatgcacaaaggttccaatttctccacattcttaccaacattttttat tttctgtttcttatttatttgtttatttattctgagacagagtctcactctgtcacctaggctggagtgcagcagggtga tctcagctcactgcaacctctgcctcccatgttcaagtgattctcctccctcagcctcccaagtaaatggaattacaggt gcccaccaccacgcccaggtaatttttgcattttttttagtagtgatgaggtttcaccatgttggtcaggctggtcttga actcctgacctcaagtgatccacccgcctcagcctcccaaagtgctgggattacaggtatgaaccactgcacccaggcca ttttttgctttttagataatagtcatcctagtgggtatgaagtggtatttcattgtggttttgatttatatttccctaat gatcagtgatattgagcatctttcaagtgcttattggccattttcttctttggagaaatgtctatgcaagtcctttgctc attttttaatccagttgctttttgttattctttttgatttgaaagtgttctttatacctcttgtatactaatcccttatc agatatgatttataaatattttcttcttttccatggattgccctttttactctgttgatagtgttctttgatacaaaata atttttaatttgaatgaagcccaattaatctatttttgtttcttttgttgcctgtgcttttggtgtcctatccaagaaac tgttgccaaatccaatgtcataaagctttttcccatgcttccttctaagagttttgtagttacagctcttgtatttaggt atttgactattttgagttaatttttgtacatcgtataaaataagaatccaatttttattttattttactttttgtatgtg gatatccaatttccccaccaccattcattgaaaagactgtccttttcctatcgaatggtcttggcacccttgtaaaacat aatttgaccatatatgtgagggtttatttctgggctctctattctattctattctattctattctattctattctattct attctattctattctattctattggtccctatgtctttctttattctagtaccaccattttgctcatcataactttgtag taagttttgaagtcaggaatcgtaagacctccagctttgttcattttcaaggttgttttgattattcaaggtcccttgat agtccatatgaatttcaggatggatttttctatttctgcaaaaaaaaaaaaaaaaaaaaaaaaaatcattgaaattttta aacagattgcattaaatctgtagattgttttgggtagtattgacatttaacaacattaaatcttccaatcaatgaactag gctatttttatttattttttctgtttctttgagctacttttgtagttttcagtgtataagtttttgctacctggttaggt atacttctaagtattttctactttttgatgctattgcacattgaatcgttttcttaatttggtggtagcggggattgtgc attgttagtacataaaaatgcaactcattttttgtgtgttgattttgtatcctgcagctttaacaaattcatgttagttc taacagacttattctatgaatcattagggttttctacataaaagatcatgtcacctacaaacagagataattttactcca ccccttcccgttgcaatgccttttatgtctttttcttgcctaattgttctggctaagacttccactaccatgttgaatag aagtggtgaaagtagacatccttgtcttgttccaatcttagagccaaagctttcagtctttcacggcctgaaagactttg taatatgt ctcaaggttaaagaacttcagaagttttctaagcaagagaccattttattaacttagttggcagcaattct gagagattagaatgaaaagatagaggataagaag atctggcaggtataatatattgagtgtgctgaatatacttttagt tttgtataggtgttaaaaaatggcaaaggaggccgggcgtggtggctcacgcctgtaatcccagcactttgggaggccga ggcgggcagatcatgaggtcaggagatcgagaccatcctggctaaaacagtgaaaccctatctctactaaaaatacaaaa aactcgctgggcatggtggtggacacctgtagtcccagctactcgggaggctgaggcaggagaatggtgtgaacctggaa ggtggagcttgcagtgagccgagatcacgccactgcactccagcctgggcgacagagagagactccgtctcaaaagaaaa aaaaaatggcaaaggaaagaatgaaaaataaagcaaggtcccagaagaggccaaaaatcttaatcaaaattgactgaaca ttacggaatgaaatggtttttcctttactccaattaacgacttcacaagaagattccatcctcgtttataagattaaccc aaaaccagcacttaaaaccagaagccttgaaaggatggagtttggggacccttctcatgtctattcccagaagggggtct tcttctggggtcctgtcccctaaagagctaggcaaaaagtatgcttgccacatctgttgaaagatagaaagttggtctaa aaatacatgagagggaactgaaacatttcagagaaggcaagactcagaagtaagaaaccaaaagaggaaggtaaaattct agttacaaagaaaagaggaatggaaattaaattgtcttacagagaaaatccagaactgccccctcttcccttactactcc atcaaaaaaggggaaaaatagtcaatgggaaagttttgagaaaaatagatctctgcattcttctggttgagaattcagac aacttgaactagagagctgggtaatttcttgactaaaggtgtgttagatctgaaagggtttttcttaaaattgtctgtgt tcatccctcccatcttagagaggaacacaggataagagacctctggagctcccccagggtcaccgagctaataggatcag agacaaagctacaaagtcattttctgacatctctccagggctctttttttctggaccccccatatcaacatgatgtattt attacattggattagcaactctccttgagctttcctcagtaccaggtttacatctcagtctgtgggtctcagagaaagta cccaatcagcagcaacattacctggaaactcatcagaagtgcccctcctcagccccaccccagatctatgcaatcagaaa ctctggaaatgcaggccagtcctaacaagcccaccagggaattctggtgcactaaggtttgagatccactgatcaaagaa ataatattccttttcttcattataatagcatgaataataactaacatgtatttcacaatttacaaaagagctttatgctc ttgttaaatttgagggtagtcttctcaaaatctctgtgaggctagaaagtcagatattgaaacacctgttttatgggttc aaagataggttcaaaagagagtaaatgattgttggggtggcaggtccagagagggcaggatcaaaactgcaattgagtct tctgccttataaaccagcatagcttccccaaggcacgtcacttctcgataaaatggtgacaactagagtgtcctttcaga tcattcttagaagcatggagtgctaggtcaattgtgtaattgatgaggaaataataatactaagaactcccatcttctac gtccttatatacaatcctgtcaggtagaagctgagtctcagagagaacaagttgccctcccaggaccaccaggtaagctc ggcatagctgtgcttagaatgtaggctgtctggcttctgggcttgcctgcccagggaggctttgtgggttctacttggtc atccagatcacagaggggcagcactgactcctacccagtgctcttgactgtacatctaatactttctactaagaaaaccc cttctctttagaccaatggttttcaaatcttggtgtgcattggaatcacctggaaagcttgttaaaacacagattgtccc accccaagagtttctgattctgtaggctggggtggggacccatgaaagtgcatttctaataaggtcccaagtgatgctga tgccaccagtgtgtggacaaccctttgagtggtgaagctctggacaccctaatttgcaaggctaatcaggcatatgtggc aaatgaatacgaactgaaattctgactccaatatcttcactgatattcctaatccatagcatacacacagtcccattcgt ttcccttttagcttttaatctacatttatcctttcttcctctgccactgccttctctccagttagctcaaaccaggtaac acataaccgcctcctaactcatccgcccagttggtttctttggctttaatctagacttcttatctccaccagatttgcct taccaaagcaccaatttcttaaggcagggttagaattaaaaatcttctgttcctcctcattgcctaaaactcctaaactt atgattcaaggtcttccatgaccttcatggaccagtctaacgttttagcctgtcctaagtgacatgcctccaccacatac ttcatgctttccactttctttctccatgtctttgttcatgcatttccatttcttctacctgcgatgtcctccttcgccat ctctgtagatttaaaaatcctacagggctcatctcaaatgccctttccttcatgaagcctttcatgaaatccccatcgag aggttttccctcctctcagctctccaaagcacagatgtctgcgtttgtggctattatcttacgttgttttgtattaaaat ttctccagctttacacatttgtcatcctcttaaggacaaacatcttattatggtcaatgtgaagctatagaggataattt aatgaaatattccaagggctagtcattacacatgactgatttatctctgtaaactcatccacactcatccacctgatttt gattggccaagttaatgaatcagagaggaaaagatggtaaaaatataataaaaatctcctaggtagtctcacatcccaca gagccccaggtaatgaaatgaggccctgagataatactttatgaacaataaaactccgggttctattgacagtgaagcaa gacctgagagagaaggctaaattcccttgtgtctagctgccacaatcttctgagaataatggcctttcttcccgtctgcc ttctgaatcataggcaaatttttctctttggtgatccctaatacagaaaggggaagtcaaataaaatatatacaaggaga aggattctgggagacagagtttcttgattcccttctgcatgctcctcctcaaaagcctttatgagcttaccttacattta aattcttttaaacaaggcattatgtggtctggtcttttccagctccacacaccttcacactacattccccccagctaatt ctgctctgggaacactgaccttcttttagttctttgaacacattgatttctggtcaagatgactcagtaacttcaacctt tgttgtgcccttggtgctgtgaagatatagatatatattaaccactgcacaccagaaatcagaaatagcacaacagagaa taaagtcattgagccatcttctgagctccaaaagacaaattttctccaaaaagacaaattcaggctctaaaacaatacct taaggaaccagaagtggaatagaaaattaaggtggtaagcagggctaaaccacatgcctgttgagcccaggtttggaaga agacaatggcaggtaggaatgtggtttctgatgggtaataggtactgttttcatttactttctgttgcttataacagaat atctgaaactgggtgctttataaagaaaaggaatttatgtcttgcagttagggaaactgagaagtcaaaagttgagggct gcaattgacaagtgccttcttgctggtggggatactctgaagagtcttgaggtggtatcgggcataccactctcagtgag gggactgagcatactaggtcaggtctttcttcctccttttataaagctatcagtcccactcttatgataacccattaatc cattaactgattagccaattaatccatgaatggattaattcattcatgagggcagagccttcctgacccaaacacctctt aaagactccacctctcaatactgccacatgggggattaaatttcagcatgagtttttgatgagacaaatattccaatgat agcagttattaaaagtacatgcttgagagaaggggattggagtcagcctcagtgcttaaactcaaaagctaggatgaggc tctaacactcctgaaagaaggagttgctgctggctccttaccagggctatatcttttacagagcaggagacctaaagagg caggaggacccggacatcgtttggaaaccaagcactaaaacaggccatctgttatacccccaatatcctctcaggacaag tgttttgaaccactcacacaaggactagtctgggcaagtgggctagatgaagaaaccacaaaatagctaagtggggagag aaagaccaaaaatactattttattcaaaatgaaaatacaatccaaaattccatgattcatgaagaaatcaaatggtatgt gttaggtggttcttgcattgctatagagaaatacctgagattgggtaatttataaagaaaagaagtttaattggctcata attctgcaggcttcacaggaagcatggtgctggcatctgctcagcttctggagaggccccaagaagatttgctcaaggca gaaggttaagggagagctggcacatcacatggtgagaaaggaagctagagagagagtgcagggtgaggtgccacaagtta ccacagccagatctcttgagaactcacttactttcatgaggacagcaccaagccataaggtgtagggagccaaagtccca tgggacatgaccaactcagcattccactggaggctatatgatcaaacagcaaactgtttatcacgaatgcaggatgtgag caaactcacaactggtcctgccaacagaaggtttgttggaggcaatcactccctggtgcctgaggtaatctactgcaaca tctagagaatgcagtcttgcaagcctactctggacagggcagctggcaccttattccatcccccttctcactatcttttt ttgcctaataaatacagagggctgtgtaaagctcagggcccttgtccactagaggcaagttgccccctgaccccttcttc caaatatactcttttgtctcttgtcttttattctcacatttgccccctttgttcagttccactaggtccgtgcgggttat atactggtgccctgagcagcaacagaatcaggctctcaacaagtgtcatccgaacatgggactttgaggacatgaacgaa gaaggtctgctggagcagaggaacagaaattgacaaggtgaacagggaccctgggacgagtctgccagcagcggatataa ggtcagttacctaaagaggtactgatcagtgccctaaagagatactgggagcagtgctttaaagaagtactgggaatggg aaattttctgaatcagggtaacaaggggaagaatttgtctattaaagaaaaacattatgtgcagttgcttaaagttgtat tggaacagtctggagcttaggttaatttgcagacactaactatcacatgcgtccgtgtgaagagagtccaccaacaggct ttgtgtgggcaataaagctttttaatcaccttggtgcaggtgggctgagtccaaaaaaggagtcagcaaagggagataga ggtggggcagttttataggatttgggtaggtagtggaaagttacagttaaaagtggttatctcttgtgggcagaggcagg ggtcacaaggtgctgggtggggaaatcatgagactctttttctgggacaggagtgtcacaaggtcaattgatcagttggg gtggggcaggaacaaatcgcaatggtggaatgtcatcacttaaggcaggaactgactatttcacttcttttgtggttctt cagttgtttcgggccatctggatgtatagtgcagctcacaggggatatgatggcttaggttgggctcagagacctgacat tcctatctttttatattaataagaaaaacaaaacaaaatagtggttaagtgttggggcagcaaaaattttttggggtggt atgtagagataaggggcaatgtttctcagggctgcttcaagcacgatcacggtggtgtgggaatctagagtgggagagat taagctgaagaaaaattttggggaaaggggtgatattctggggttgttagaaggagcatttgtcata agaatgatgatg gcctggatgtggttttgtatgaattgagaaactaaacggaagacacaaggtccaaataagagaaggagaaaaacaggcat taaaggattaagaattgggaggacacaggacatccaattagagagtgcccaagggggtccagtgtaattatttgcctgga caatgagttttggggctctattaggttgtcatataccaggccagattgatttaggtaaaaacaacactcttcatttaaaa tatacagagtcctccttttttagcagtgagtaagttgagacctattcctgtcttcttatattaataagtaaaataaagca aaatagaggtgaagtgttggtgtcatgaggggaacaggaagcagttcggtcctatttgcaaattgattttgggggggtaa agaaaactagtgtacctttgcctgtccaattaataagtagacacatgtagatggaggagccacagaggaagaagagaact ttgtaaggcaaaactggaaatgtaaagggaaaagatgagagggagcaccaaaagaggtgtcttgcacccagactcaggga tctagtgagagcagcagctgttagaggttgtaatggggattaatggggctactgggtagagggggaggttcaacttttat ggtgtatgagaaagcgcatagtgtctacaagcaacctttcattgctattcataggattgggtataagtaaacaagaaggg ggggctaggaggagagtctgaagaacaaggggaaggtagccaaggatggagtgaaatgtagggcaaatgtcttaaaggaa atgagaggttctaagaggagggctagtggcttgtaacccacatggaagaggttacgaaaggatgatagaatggaatgagc ctgtgaggctggaaggaggaattttccttggtccaagaaccatttgccttgtgtgggaagagtttgataggtggaagttt cagtgggagggtaggcgggagtgactgatgagaaggagaaaaactggccataagggacagaagttggaatgctagctgct cctttagctaccttatcagcataagctttgccctgagtgatgggatctgatgccttttgatggcgcttgcagtgaatgac cctagcttccttggaagtagagcagctttaagaagagtttttatgaagaaggcattaataatggaggaccctcgtatagt gaggaaacctctttcaggccatataacagaatggaggtggagaatatggaaggcatatttagagtcagtataaatactga cacacaatccttttgcaagagtgagggctcgagttaaggcaatgagttcggcttgctgagagggagtggagtggggcaga gtggtagcctcaatgatagatgtgaaagatactatagcgtagcctgcctttgctggtgagtggtgattaggcctagtgga actgccatcaataaaccaagtgtgatcagagtgaggaacaggaaagaaggaaatatgggaaaatggagtgaatgctaggt ggatcagagagatacagtcatggggatcaggtgtggtatcaggaataatgtgggaggccagattgaagtccaggccagga acaatggtaattgtgggagactcaacaaagagtgagttcaactgaaggagccgggggagggggagagcggcagaaagtat atgcatcaggtgtgaggaagaaaatacattttgaaagttatgagaactgtagagagtgagttgatcatagtttgtgattt tgagggcctttaaaagtattaaagcagtggcagctgccacacacagacatgagagccagcctaaaacagtaaggtcaatc tgtttagacagaaaggctgcagggcactgtccaagctcttgtgtaaggattctgaccgcacagccttgtactttggctgt gtgtaatgaaaagggttgggatgagttagggagagctagtgtgggagtagcttctagggctgtttttaaggaacataaag aggagtggggaaaggatttaggatctatggggtcagctaggtttccttttgtgagtttatgtaatggtttagtcaggatg gcaaaaccaggtatccaaaggtgaaagtacccaaccatgtctaggaaggaaaggatttgttgctttgtagaagggattgg ggtttgggagattagccggacacagatcaggagggagagcacttgtatttttatgaagaattatgccgataggtaacgga tgaggaagaaatttgggctttggagggggatacacgatattcccttgagaatagatgttggaggagcaggagggtgtcct gttgggaagattcataggaggggctataaagtagaaggccatcaaaatattgaataaggtgacaagcagatggacagaaa agtaaattatgagaaagggcttgactgaagtaatggaggctgtccctgaagccttgtggcagtacagcccaggtaagttg ctgagactgatgggtgtcagggtcagtccaagtgtaagtgaagagaggctggggtgaagagtgcaaaggaatagtaaaga aagcatcttcaagatccagaacagaataatgggttgtggagggaggtattgaggataggagagtatatgggtttggcacc acagagtggataggcaagacaatttggttgataagctgaagatcctggacaggctttagtcccttcaaagcctgttgtgg gatgggatactggcattgagcaggataagggtaattaggttttaatgggatggtagggttgcgtgatcggtcaccaagga gggagtagaggtatcccatacttgtgggttaagatagggagtcaggaggggaggttgtgaaggaggctttgaactgggga aaagggtggcaatgaggtgtggctgtagcccaggaatagtcagggaagcagataatttagttaaaatgtctcaatttaat aagggagctgggcaggtgggaataactaaaaaggagtgcataaaagaatgttgtccaagttggcaccagagttggggagt tttaagaggtttagcagcctgaccatcaataaccacaacagttatggaggcaagggaaacaggcccttgaaaggaaagta atatggagtgggtagcctccatattgattaagaaagggacagacttaccctccactgtaagagttacccaaagtgtctgt gatgatccaggaggcttctgaggtgatcaggcagtgtcagtcttcagctgctaagctgagaagatctgggaaggagtcag tcagagagccctgggccagagttccaggggctctgggagtggctgacgggcaagttggacagtccgatttccaatgcggt cccacacagatgggatacagtttaggaggaatcctgggctgtaggcattccttggcccagtggccagatttctagcactt gaagcaagatcctggaggaatgcctgaccacagtggtttaggtgttttgaagttcttgtgtgctggagatgtggctgagg tttttctcacagcagaggcaagtaattgcaactcagaaatacattgccacttggctgtctcttctctattattgtacacc ttgaaggtgaggttaattaagtcctgttgtggggtttgagggccataatctaatttttgaagcttttttaatgttgggag tggattgggtaataaaatgcatattgagagtaagacagccttctggcccctctgaacctagggcagtaaaatgtctaaga gttgttgccaaagggaccatggactgggctgcgttttcatatttgatgaaaaaaaaagagcctaaatgctaactaatttg ggagaggtcagataaagtaaaaggaacattaatcttgactatgccttcagctcttgccacctctctaagaggaaattgtt gggcaagtggaggagtgctagtcgtggaatgaaaccataagctggactgggtgtgaggaggggaggtgatagaaggatta cagcgtaggggagtagaggctgaggaagaattgggacctggctcagcctggtgaggagtggcctggtgaggagcagcctg gggaggaggagagaggttagatgggttcgtagaaaagaaggattcaaaggactcggagcttggtgaggagactgaaggaa cagacaggagagaaagaagaaagatttgggacaagtcgcattgggagcagagactaggaagggagtgatgtgtaaagaat gcctggacatcaggcacctcagaccatttgcccattttatgacaaaaattatctaagtcttgtagggtggagaaatcaaa agtgccattttctggccatttggaacaattatcgagtttgtattggggccaaatggtgttgcagaagaaaataagatgct taggttttaggtcaggtgagagttgaagaggttttaggttttttagaacacaggctaaggcagaagaaggaggaatggag ggtggaaggctgcccataataaaaaggtaagtttagagaaaagagaggatagagacacagagagagggggtggtggtact catcagccaggggaggtggtacttgccaccaaggtgatggatcaaggcagtcatccccacggtgatcagacacctctgaa atgtgggtgaataatcaggcaggtgtccctgcagtgattagacaccaaggggagactgtcttcccgagtccgtgaccggt gctggagttttgagttcacagataaaacacatctcctctgtctctaccagaaagggaaaggaactgaaattaaggaaggg agagattgaagggtggagagatagcaagagagttggaaaagagaataaaaagaggccacttactcaatttaaaattggtg agatgttccttgggctgatctgaggacccaaggttgtaggtggatctcctcacggaatgagggtgaggacaggggactgg tctccagaaggagttcccgagtcctggatcttcagcaccaaatgtcatgtgcatccatgtgaagagagtccaccaacagg ctttgtgttatcaataaagctttttaatcaccttggtgcaggtgggctgagtctgaaaaaggagtcagcaaagagagata ggggtgggtcagttttataagatttgggtaggtagtggaaagttacagttagaggtggttatctcttgagggcagaggtg ggggtcacaaggtgctgggtggggaaatcctgagacttatcatccagggaaggagtgtcacaaggtcgattgatcagttg gggtggggcaggaacaaatcgcatggtggaatgtcatcagttaaggcaggaactcactatttcacttcttttgtggttct tcagtttcttcaggccatctggatgtacacgtgaaggttacggggatatatgatggcttagcttgggctcagaggcctga cactaacctcctgcagaagccacaaaaggttattacacataaaccatggtttccacaggcaggcactcttgatgtggaaa attgggatagagcaggattaaaacaagctcatcaaaaaggtcttaaagttgattcttcagttttctccacttggagttta gttcatactgtacttctgccattatctccttattattctgcggaacagcaggctgaatctaaaaattggaaagaatttgt tgtcctactcacagctccaattgaatataaaaaacaggagagggaggataaaaattggcctataccgcctcctccagatg cagaaacatctgtaccatctccttcagtggcagaaatagagatcccagtacaaagaattttatgctctgctgtcatagct ggagagcccttaggaccttgtgcttttcctatttctgtaaggcctgatccaaataatccacagcagtttattcatgaaca ctctccactagaatttaagttgttgaaggaattaaaaactagtgtggtcaataatggagtacaaagccaatggttcctgg aggaaggaatgctagacatagaactttgggagcaagtggggagaaatcttaaacaacaccaggcacaaaggcatcaggtc ccagtaaaatcttttatgttaggggctttgagtagagcagccctggttgttacacacaaaagagcctaaaaagggaaagg aggaggaaatgtcacctgccttatcacctccccttccctcagtgccaatatcactgggccaaaataacaaagaggaaatg gaggtcttacctaagcttcctcctccaatagataggaagaaggacagaggatacgctacagctatcagtccctgtcttaa gcaggcagcattagaaggagagctcttagccgggtgcagtggctcatgcctataatcccagcactttgggaggccgaggc aggcagatcatgaggtcaggagatccagaccatcctagctaacatggtgaaaccccgtctccactaaaaatacaaaaaat tagccaggcatgttggtgggcacctgtagccccagctacttgggaggctgaggcaggagaatggcatgaacccaggaggt ggagcttggagctttcagtgacctgagattgcaccactgcactacagcctgggcaacagagcaagactccatctaaaaaa agaagaagaaggagagctcttaacctgctcagtaatgcaaaatcggcaaggcaatcaggtgtatgtttataaaaagataa gaaaaaggcattagaagccaaaaccacgtggccaagcaggcagtgggcaggagaaaatgctcagaggcagaaaagctcac agcgacaaagccaacaaggtctgcccaggacggcagcatccctctggcaaaggagcaagggagcagcacagacacaggca aagcctaaacaagtacaatgtggccacctcccaggacctgcaccactgccctctggctctgtgggcagcccattgcaaaa tttcatgtgttacatctcaggctatgattctctgctaagatgtaagtaaaatgtaagaatttgaaaagcatcttttctaa taatggccactattgtcatctctctcctatccctgatgtagctttccaaattcaatttaagtaaaacagtaacctttgaa gggaaagagattacagagggcccatgaattagttgaagagtaattaaaagctaggcatgtaaaaccacacattacgcttt aaagaagaaatttaaacctaattaaatgatatttgttaaattagaaggtaaaaatgttgtgccctgttgggaacaggccc ccaaatctggccataaactggccccaaaacaggccataaacaaaatctctgcagcaccatgacatgtttgtgatggccat gatgcccaccttgaaggttgttggtttactggaatgagggcaaggaacacctggcccacccagggcagaaaattccttaa aggcattcccaaaccactaatgatagcatgagcaatctgtgccttaaggacatgttcctgctgcagacagctagccagag cccatccctttgttttggcccatccctttgtttcccataaggaatgctttcagttaatctatgatctatagaaacgatgc ttatcactggcttgctgtcaataaatatgggagtaaaactctgttcagggctttcagctcagaaagccataagccccctg atttcccacttcccaccctttatttctgtgtgtgtgtcttgaattcctctagcgcctctgggttatggtctccacaacca cgctggtcttggcagtgcccttctcagaaagtgaaaaagagttgtatgtaagtgtagtgaaaacataagcatgaatcact gtcttaacccactgattagatagtctttgatttgtacttgctaaaagagtcctaaattgagttcctcagctagtgagtca ctgttttcaagactgtttgccagattgaagtccataaacttggtcagcccgaaaactcaattacaagatctaagctattc tgcctgtggctttaagcacatggttaaagtatattatttaagtctctccttctagatatgctttcagattttctttttaa acttcttgttacttatttcagctttccatattgataattaatgcagtcaattgctcagttatgactgtgatatcatcagg attcctttaagtaaaaggcaattcaaagcggtattgcactcccccatacctaatgctttaacactgtttactgatgggtc tggtaaacatggaaaagctgcagtctagtagagaccacataattcaatcactcgatctgagttcactagcactcagagag ctaaggttactctgtttatttattaaagaatttttacaaccttaagctcactctggactttccagccttatgtggcaaat gtagccatcaatttatggggtcaagacttacttacagcatgggatatgaggcttacaaatgagactttgataacccagga ttttaaatgttgaagaacacgggatatcagagtgaaaaaggtttagggaaaattctgacaagggaaaattctaacctgat atcaataactggaaagacaggttaaaccctgcaaggggatacattgacattttttcttcctcacttgctcttttctgctg tctgaatatgggcatgagggcaagagtcattttagaαcaccaagtgaccttgaggatagaagccttatactagaggtggt gggaaagaaaaaacagaaggactcataaagaaaaaaataataaacctcagtattaagatggaaaaattcccccaattggt ctataggttgaacttcatctctattaaatttcagctatgtttttgcagaatttgatatgctgatcataaaatttatatga aaatgcaagagacacagaatagtcaaaactttgaaaagaagaaagttggaggacttacacttgttgattttaaggctttt tacaaagctataataatcaagacaatgtgttactgacataatgatagacatattgatcaatatagacaatggatgaatgg agtagaattgacagtctagaaataaaaccttatatatatggtcaatttatttctttatgtattctgtcatccagaataca taaagaacaccttcaactcaataacaacaataccaacaagggtgccaagaccaatcaatggaggaaataatagtcttttc aagaaattttgctgagacaactaagtatttatatgcaaaataatgagtttgaatggctaccatatacaaaaattaactca aatggactatattaggtcagtgcaacagtaattgcagtttaccaccattacttgttttttttttttggtttttttttttg agacagagtcttgctctgtcacccagaccagagtgcagtggcatgatctcagctcactgcaagctccacttcctgagttc acgccattctccttcctcagcctcctgagtagctgggactacaggcatctgggtaatttttttgtatttttagtggagat ggagtttcaccatgttagccaggatggtctcaatctcttgacctcgtgatctgcccacctcagcctcccaaagtgctggg attacaggcatgagccaccacgcctggcctaccattacttttaatggcaaaaatgcagttacttttgcaccaccctaata gaactaaatgtaagagctaaaactacaaaactgttagaagaaagcataggagcaaatcttaatgacatgagagttggcaa ttgttttttagatatgacaccaaaagcatcaaggacaaaagaaaaaaatggataaattggacttcctccaaattaagaga acttttgtcctgcaagcaatactattaagaaagtgaaaagacaagtcacaaaatgggagaacatttttgcacataatata tttaataataggctgacatccagaatacataaatacctacaactcaataccaaaaagacagcccaatttaaaaatgggcc aaggatatgaataaacatttctctaaagaagatacaaaaatggtcaatatgcacatgaaaagatgctcaatatcaatatc tattaggaaaatacaaattaaaacacaaaatataaaacacaagatatcaatttacactcaccaggatggctgttatcaaa aagacagataacaagtattggcaaggatttggggaaattgtaaccttcatacattgctggtaggaatataaaatttgcag caggtttggaaaacagtttagcagtttctcaaaaagcctgggcatggtggctcatgcctacaatcccagtgctttaggga gctgaggtgagaggattgcttgagcccaggagttggagaccagcctgagtaacacagtgagacctcttttctaccaaaaa gaagagagttaaacatagggtaccatataagccagcaatccatctcctagatatgtacccaagaaagttgaaaacatata ctgacacaaaaacttacatatgaatcttcatattagccttataataatagccaaaaagtagaaacaacccaaatacccat caactaattaaaatatggtgtatctatacatattatttggccataaaaggaagtactgatacatgtcataacacaaatga accttggaagcactatgatctctgtattagtcagctcttgtattgctataaagaactacctgagactgggtaacttataa agaaaaaggcttaattgagtcacagttccacaggctgcacagggatcatggcccaggagacctcaggaaacacagttatg atggaaggaagagagtgaaggaggaggtgctacatacttttaaaccaccagatcttgtgagaagtcactcactatcatga gaacagcaagggagaagtccacccccatgatccagtcagccccagccaggccccaactccaatattggggattacaattc cacatgagatttgggtggggacactaatccaaacaatatcattctgccccagcccctcccaaatcctgtgtccttctcac attggaagatacaatcatcccttctcaacagtttcatttcagtattaactcaaaaatccaaagtctcatctgagacaaga caagtcccttccacctatgagcctataagatcaaaaagaagttagttacttccaagatacaatggaggtacaggcattgg gcaaatatatccattccaaaagggaaaaattagccaaaacaaaggggccacaggccccacgcaagtccaaaatcaagcag ggaaatcattaaatcttaaagcttcaaaatgatatcctttgactccatgtctcacatccaggccacaccaatgcaaggag tgtgctcccaaggccttgggcagctctaccctgttgctctacagggtatagcccccatggctgctttcacaggctggcat tgagtgcctccagcttttccaggtacacagtgcaagctgttagtggatctaccattctagggtctggaagattgtggccc tcttctcatagctccagtagacagtgccccagtggggaatctgtatgggggctgcaaccccacatttctcctctgcactg cccaatagaggttctccatgagggctccattcctgtagcatacttctacctggacatccaggtgttttcatacatcctct aaaatctaggtaggggctcccaagccttaactcttgccctctgcacatccgcaggcttaataccacatggaaaccaccaa tgcttatggcttgcaccctatgaagcagtagtctgagacatatctgggcccttttggccatggctgggatgcagggaaca gtgtcctgaagtggcacagggcagcggggccatgggcctggcccatgaaaccttctttcctcctaggcctccagacctgt gatgggagggtctgcctcgacggtctctagaatgtgtttgaggcatattcctcattgtcttggctattaatatttggctc ctctttacttatgcaaatttctacagcctgattaattcctttccaaaaaaatggggttttcttttctactacatggtcag gtcacaaattttccaaacttttacgcttccctttgaaatgtaagttccagttgcaggtcatttctttgatcacaaatata agcatatatttgtagaatcagccaggccacatcttgaatgttttgctgcttagaaactgcttccaccagataccctaaat cattgctatcaggttcaaaattctacatatctctagggcaagggcacaatgcctccaagacctttgctaatgcataagaa aattgacctttgctccagttcccaataagttccccatcttcatctgaggtctccttagcctggacttcattgtccatatc agtatcagcattt catcacaataatttaactagtctctaagaagttccaaactttcccttatcttcctatcttcttctg agccctccaaactgctccaacctctgcccattacccgggttccaaagctgcttccacattttcggtatctttatagcaat gctccattcctgataccaattttctgtattagtctcttctcgcactcctgtaaagaactacctgagactgggtaatttat aaagaaaagaggtttaattgactcacagttccacaagctgtataggaagcatggttcagaaggccacaggaaacttacaa tcatggaggaaggcgaagagaaagaaggcacgtcttacgtggctggagtaggaggaagagagtgaagggggaggtgttac acacttttaaacaaccagatcttgtgagaactcactcactatcatgagaacagcaagggagaggtctgcctccatgatcc aatcacctcctaccaggctcctcctccaacattggggattatgatttgacatgagatttgggtagggacacaactccaaa ccatatcaatcccatttatatgaaatgtccacaatagataaatctatagagacataaaatagattggtgcttgcctagtg ctggacgtgacaggagggtgtgagtaaaagaggcaatggagtgataggtacagggtttctttttggggtgatgaaaatat tataaaattagattgtggttatagttgtataactcttgaatatcctaaaaatatattgaattttccatttccattttaaa tgggtgaatcttatggtatgtgaattatatctcaataaaactgcaaaaaatgcacaatttgcaattgcaaaaatatggaa ccagtccaaatgcccatcaatgagtggataaaggaactgtggtatatatatatatatatatatatatatatatatatata tatatatatatatatatacacacacacacacaccatggaatactactcagccataaaagggaataaaacaatggcattct cagcaacctggatggaattggagaccattattctaagtgaaataactcagtaatggaaaaccgaatatcatacattctca ctcataagtgggagctaagctatgaggatgcaaaggcataagaatgatataatggactttgggaactcagggaaagggtg agagaggggtgaggaataaaaggctacccattgggtacagtgtacactgttcaagtgatggctgcaccaaaatctcagaa atcaccactaaagaacttatttacataaccaaataccacctgtttctcaaaaacctattgaaattaattaatttttaaaa actgctgaaatcaatagtgaaaggatggactattcaataatgacacagttaattgaatatcatattttaaaaattagate cttacctcacactataacataacaataaattccaggtgaattatagaccaaatatgaaaagcaaaattttaatattttag aagacaatttttatgaccttaagttagaaaatgatttttaaaaacaggatgcaaaaacactaatcataaagagatatttt aggccaagcatggtggctcacacctgtaatcctagtactttgggaagctgaggcaggtggatcacttgaggtcaggagtt caagacaagcctggccaatagggtgaaacatgtctctactaaaaatacaaaaattagctggaaatcgctcgaacccagga ggcagaggttgcagtgagctgagattgtgccactgcactccagcctgggtgacagagagagactccacctcaaaaaaata aataaataaaaataaagagagattttaataaggtgcattaaaataaaaaactatccatcaaagacaccatgaataaagtt aaaataggccacaatgagaatatatttgccatgaattttttctttttttttgagatggagtcttgctctgtcacccagge tggagtgcagtggtgcaatctcggcttactgcaaacttcacctcccaggttcaagcaattctcctgcctcagcctcctga gtagctgggattacaggtgtgtgccaccatgcctggctaatttttgtattttttgtagacacggggtttcaccatgttgg tcaggctgagctcaaacccctgacctcgtgatccaccttcctcagcctcccaaagtgctgggattacaggcatgagccac cgtgcctggcctaccatgaatatttttttaaaggtagcatccagaattaataatcttctccaacaaatttcattagtagt cagggaactgcaaattaaaatcaaagtaaaatactactttccactcattagactaaaatccattcaagtctgataatacc tagtactgagttggagtaatagaaactgctaatgggacagttagttggtcatcactttggagagaaattagtcagtatct agtaaaagttagtgatacaccttccattttcatctgttctgtgctgctaccaaagaatacctgagactaggtaatttata aataatagaaatgtatttctaatggttctagaggctgagaagtccaagattgaagggccagcctctgcagagagccttct 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tagttttttctatttcctggccttcgcatgcactgttaactttacctggaattctttatgcagtaattaagagcaaaggt gtagagcaagactgcttgagcttggatcccagcactgagttgatttagggagaataacttaatctcttaatcccaagaga aaatatgatataatagttttgagctcataaagttttcataagcattaaatgtgacctatatatgtaaagcaatctaacag tgcctatagtatttataagtgtctgcattaccaaattcatcattatcatggcatgtcatgtcaccatccactacattacc atcactgtcaccatcatcatcatcaccaccaccatcatcattaactccctttgtctagtcaattcatatttgttcttcgt attttagatacctgttaaaatattttttcaaagatgtctactctgattcttcagtacaaatttgatttaataagatccta tcattttgtccaaatacttataaaaatttgtagttctatatttaatgtgttttgtttgtttaacatctctctcctacatt gtgttaagttttttaaagagaaggtaagggttaaagagagacatagagagagaaagagagacagagagagagagagagcg gttctacagcaatacaggtatattagaaaaacctgcaaaggtggggaccagcttaatgccagagccccccactgcttata ggctggggtacttataggtctgggggtacttataggcctgggtgggtggggtctgagcagtatggcttgctgcccaagaa gatgttgataagacgttcccatgatgaggcagtttggtccttgcttccatagagtgtgatgcttcttgcactttttccca gcagaatgtggtagggatgttccttcaggtgggcctttgcctggcagggtatgataaggatgttcctgtgccttggaatc aggtagttagacaggatgtttctcacagcctgaacccccatggaatgtttcactttgaccagggtctgcgaaatagcagg gggcttacaaaatggtgtagtttggactaacaccttggaacacaaaagtttcttggggccaaggctggcgtattagtctg ttttcatgctgctagtaaagacatacctgagactgggtaatttataaagagaaaagaggtttaatggactcacaattcca catggctggaggcctcacaatcatgagggaggcaaaggaggagcaaaggcacgtcttacatggtggtaggcaagagaacg tgtgcaggggaactgccctttataaaaccatcagatcttgtgatacttattcactatcaaaagaacagcacgggaaaaat ctgcctccatgattcaattacctcccaccagattcctcccatgacatgtggtaattatgggaactacaattcaagatgaa atttgggtggggacacagtcaaaccatatcagctgggtatgttttattcacctttttatacccattgtcatgtcttctgg acaaacaatggatgtaaaatggtatagactcctgagtactcatttgttgaatgacaaatctatgaaccatttgaccagta tgcagcagccattaaaattatgtttatgaataatttacagcatggaaaaatttggggttgctagtagaaaaacaaaaagg tacaaaaggatatatataataagcctacaatgccatataaacaatactaacagcaaaaacaaacctataaattgggggaa gatggggcagatagaagtaacctaaaatactaacatgttgttttggggtcatgaaattataaatgattatgcacccctta atttttactttctatgtttgatttttctatggtaaatgcatttttattgaggtggaattcacataacatgaaatgaaaaa tttagtggcatttattatattcacaatattgtacaaccactagctctacttccaaaacattttcatcactccaaaataaa accttgtacccattaagcagttactccccattatttcctctcttagctcctagcaaccaccaacctgctttctgtctcta gggatttatttattctggatattccataaaaatggaggcacaatatgtaccttttatgtctggcttctttcaccaagcat gtttttgaggctaatccacattgcagcatgtatcagtacttcatttctttttatgaataactgtatacagaccacaattt gttatccattttttggtttatggacatttgggttgtttccatctctcaactattgtgaatagtgctgctatgtatatttg tgtacaagaatttggttacctattttcaattcttttatgtatatatctaagatgaaattgcagggttatatgctaatcct atgtttagcatttttttttaggaaccattaaactgttttccaaatctgatgccccattttatattcctactagcaatgta agcaagttccaatttctccatatcctcaacaacacttgttattttctatttttgttatagccattctaatgagtgtaaag tgatatatcattgtggttttctttgcattttccttatgaacattgatgttgagtaccttttcatgtactttttggtcatt tatatatcatctttggagaaatgcctcttcgtgtatgttttgcccattttaaaactagattgtctttgttgttgacatgc atgcattctttaaatattctgcatactaggcccttatcagatatatgatttgcaaatgttttttctcattttactggctg tcttttcactttattgataatgtcctttgatgcccaaaagttgtttattttgatgaagcatatttatcaatttatttctt ttattgctcatgcttttgatgtcacctctaagaatttataaccaaatcagaggtaatgaaggtttacccctctattttct tctaagagttttatagttttgactcatttacttaggtcgctgattcatttttagttaatttttgcatatgatgtgaggaa gaggtccaactttactcatttgcatgtggatattcagctgtgccagcaccatttgtgaagagtctatcatctcctcattt aataatagtattgacacctttgttgaaagtcaattgataataaatgtatgagtttatttctggaatctaaattctattcc attgatctacatgtctatccttgtatcagtatcacactatcttgattactgtagatttgtagtaagttttgaaactagaa agtgtgagtactgcaatattcttctttttcttttttaaagattgtcagggcctcttgcaatttaatagggatatgaggat tgacttttctattctacaaaattaaaattttgttagagattgcattgacactgtaggtagctttcagtaacattgccatc tcaacaattttaagtattctaatacatgaatatgagctttctttctctttatttaggtcttctttaatttctttcagcag tgttttgtagttttggggtacaagtctttcacctttaaattttggtgaaatttattcctaggtattgcatttttttatgc tattgtaaataaaattattttctcaatttcctgttggatgttcattgcaggtgtatagaaactcaactgattctttgtgt tgatcttatgctgagaccagctcagttggggagaccctaacctagaagcactagaggaattaaagacacaaacacagaaa tatagaggtgtaaagtgggaaatcaggcgtctcacagccttcagagctgagagcttcaaacagagatttacccacatatt tattaacagcaagccagtcattagcattgtttctatagatattagattaactaaaagtatcccttatgggaaacgaaggg aagggctgaaataaagggatgggttgggctagttatctgcagcaggagcatgtccttaagtcatagatcactcatgctat tgtttgtggtttaagaatgcctttaagcggttttctgccctgtgtgggacaggtgttccttgccctcattccggtaagcc cacaaccttccagcgtgggcattatggccatcatgaacatgtcacggtgctgcagcggtttttatggccagttttggggc cagtttatggccagattttggggggcctgttcccaacaatcttataccttgcaattttgctgaatttgcttgttaacttt gatagtttttttgaggattatttgggattttctacatatcatgtcatctgtgaataaagatagttttgcttctttctttc tcatttggatgccttttatttccttttcttgcctaatttccctggctagaacttccagtatgatgttgaataaccatggt gaaatgggcattcttgtctttttcctgatgttagagagaaatttttcagtctttaaccattgagtataatgttagctgtg ggttttttacaaatatcttttatcatgttgaggaagttccttcctactcctacttcttggagtgtttttgatataaaggg tatttaatttgtcaaatgctttttctgtgtcagttgagattatcatgtgagattttttttccttcattctattagtgttg atgttacattggttgattttttatgttgtactacatttgcattctttatataaatttcacttggtcatggtgtataaccc ttttaatatgccattggatttagtttgctagtattttgtttagagtttttgcatctatattcataagcaatatcagtcca caggttttttgtggtttatttgtctggctttgctataatggtaatgctgtcttcttagaatgaatgagggagtgttttct cctctttcattttttaaacgtttgagaaggagtgatattaatttttctttaaatgtttggtagaacttaccagtgaagcc gtctggttcttaacatttttctgtgttgggaggtttctgattaccaatttgatctctttaatttttacagatcttttcag attttctatttcttcttgagtaactttttagcaatttatgtattttagaaatttgttcatttaatctaggttatttaatt tattggtgtgcattttttcatagtattatcttataatcttttaatttttgtaaagttgataatgtccccaccttacctga tcttagttatttgtgtcttctctgtattctttttgtcttcttcttctgtcttagcatagctaaaggtttgtcaactttgt tgatcttttaaagagtcaacttttgctttcagcatgcattactttttaaatagaaatatatacacctaagttgcattaca aaggagttgtcctccacacacttattctttcccaccatcagaggtttatggtccccgcaaaagtcaccatcagttgggct caactccaatcagtcatggtaggtcagggtccatctcattgtctccatcactcatgcccacccagggtaagtctaatcat gttcaccaatcagaacctctgccacatcagctctgtgggtttcctctcatgccatctgtaccaacaatgagcacagtctg ggtttcctgatgttttctatagcatggtgcccctccctgggacacctcagaagccacaatgatattcattaaacttcttc ctgcaagtactccctctattgctccttctactcaccaagcttagtgtcagggaatatgctggtggggagtatgaatctta gcttctcactcccagactcggctcccaacctgctgttgccaagtcttggggacatctataaatgccttctaaatacctgt cttggcctatccccagccacagattcctccctagagcaggctacctctgaggcatctatactgagatcttaatcacagag acatttaaaacatctaggctacaaaagaattcctactatagggttcaaatgaatttctttccgtcacttgagacagcttt ttagcaagtacatgtattaaagattctgatttccccttttttctcctacagtttgtttggcctaaaggtatgacatctaa tctgctgcatttacactctaagtcaaaattaccattttgttcttttaatttctatttctaatcatacattcttgtctact cctggttcatctggagacaaagttgaacttagaagatggaggagaaattcttatctgccctctgctagttgacacttcct ttccaagaatcatttgcagttgctgggctttcttgctgtgactctatgccctgttgtgttactttttcatttgtgacaaa aacagtggtaatagtttgcttcatttttattatgaagacttgaccaggataggtaggaacataattactgctttttctgt gggcatcatattggtccagatcatgtttaaccagaattgaagatgtaaaatcctagaactcactaatctattttagtagg tcacaggaagcatgcaaaccataaaaaccgcaatgaaccaaaagcatctgtgttgacaagaggcaagaatttctctattt tctaaaggcactaactgaacaaatctattgcccattacttaggaaattgctaagggcatcgttaaagtacttcaggctgt tgaaaaaccttttctgtcttcttgccccaccaccaattctctctagctatgctttctctcacatgttcttgccatccatg gagtggcagagaggttctgagtacaactctaactttcagtttcaatggcctaatccccaactcaactgctgaccttgagt gtaaaaataaacaagatcttaaacatcttagggccagcattctgggtcttcttttgttatttggggagcataaactattc tcatatcattggcttgcagaaaaattgagcttctcctcttccttgccccatgtcaccttgaggtgaccacagccctgcct tctatgtaatcctgcttggtcagcaggcacatcagagctcagtggcttgtgacatactttccttcaagcctgctcgaagg gccatactcatcattgagactgggaaccttagaaaccatgaacccagtgccaatgggtagatacagaattctcaaactca tgaaaaaacatcctttttaactctctccgtgtgcataaagaattctaagatgtactgatcaagattcccaattttctaac tatctattaatatatggacgaggtaagaagaaagttgcaagaaaaaaatttgtttgacttgacggttgtgtggttatttg ccacactcccccagatccactctgagtcccaggatgctgattttaggggctacattgcctagactgtccattattccctc ttcccatctggttcagtcactgggaagcactggtaggaggtcagagtgggagaaggaggttaggatactttctgcccctg ctgtcctactgctttgctgaacttctagcagtggctgagccatcaacctgcagctctcaattccagctgtctgtagcact caagtggtattgtttattcttttgatccttctagctgttaaggaagaaaaaaataattttttcctcaatgctcataagtt cttggaatggacccctgtaacaaaagacagattaacacgagaaaagtttattaacgtacatattttatacgtacatagga gctatccagggaatgaataattcttaaaaaggtgactttgaattccagctcatatagcatcttcaacaaagttcagtaac attttagagatatgacaagacaaagaaaatgaactttgagcctctagggacagtgacttgtaggaaggcaaaaggaataa atggaggtaaaggctggttagtaatacttgttaatgaagattcctctggtgccatctccaggtccacaaggatttaaatt tgtcttcagtggtgaacctttgttcaccctggcagaaggtgtggaggggggtgcagatccgttttgtctttgtaagtcta tatcctgcttttagacaaataaagggagggaaaagagctttccttcatctgcttcttaattgccttcagctcaacaatcc ttatgcaaaagaggtacattttagggtgtcaaattctggtctcccacaaagcatagggatgacagaccacctcaccatcc ctgttgcttcttttaagcctgctcacccctccaaaaatattttcattctatactgtctcttcaaaatctcagcggagggt gccctctgttatcctgccctctgtgtcagtataagccaaaggtttgaatcctggctctgcaactatctacctctgtgcct ctccttgtttatgaaattacagggctggagacaaagatcacaatgtgaagacaaaattggagagcggtcctaatcagcca gagcaaaatttctggctcttgctcttccccatcctgggttgaatcataggaacaggtggcaagatgccagggtcaggaga ttccagaagtggcagcaagctcagtgttaccaggtcagggatgacctgtcttattattgaaatctcagagatatgctcca attccggcccagagacacattgagagacaactggggaacttgctatgttcctgaacaggcaatgagctgtcttccaagaa aaaacctgagacccttcaagtctcaggtcttacttagcacatataccaggtcttacacaggacacatggttacaactgac tgaaatctgggctgggtgtaggagctcacacctgtaatcccagcccttcaggaggctgaggcaggcagattgcctgagcc caggagttcgagaccagcccgggcaacatgacaaaaccccatctctacaaaaaatagtcaggcatggtggcatgcacctg tagtctcagctacttgggaggctgagatgagaggattgcttgaggttgagactgcagtgaagcatgatcatgccaccgca ctccagcctaggcaacagagcaagatcttgtcgcaaaagaaagcaaaaacacaacataacacaacaacaacaacaacaac aacaacagcaaaaaagccaacttcttgaaatctggaaaggacacctggactgccctgagcatttgattgttgttggctct agcagtggatgcatccttcaacctctggcactctgcagggctcagactgttctgttctgtttgttacctgtggagtgcct gccagaccctgctctagctgctttaggtccatttaccctcatagacccccagtcttgttattcatatttcatatttggga aatggaaacttagaaacttgccaagtccacagcatgagatcctgcctccggtgtctgctggattccagaaagtgccaggg gccaacttagatgacaccatgttctctgcacaatcttaggaatgctcctagtctgatgtccccattgcaaaatttacatt atcttttaacaaaacgtctttccaaggaggggcatttaaaataactgaggttcttcttgctaaggacgttcctgacacaa gagataatttagcatttccttttcattaaaaagtttgaaatcctgtaatttgtgataatgtggatgaacctagaggatgt taagtgaaataagccacacacagatagacaaataccacgtgatctcactcttatgtggaatttttttttaaataagttgc ttagccgggcatgatggcacacacctgtaatcctagctactcaggaggctgaggtgggaggatggcttgaactcagaagg tggaggtagcagtgagctgagactgtgccagtgcactccggtctgggtgacagaatgaaacccaatttaaaaaaaaaaaa aaagttgctatcttagaaaaagacagtagagcagtggttaccagagactggggaggaaagagaggaggtgagaatgggca gcagttgatcaacgggtacaaagttaccatgagataggagaaacaagtgctggtgctctgctccaagtagggtgacggta gttaataatgaattctgtatatataaatagctagaagagagggttttcaatatcatta tatttcaaaagaaatgataaa tgtttcagaggatggatatgtaattaccctgatttgatcattgcacaatgtatacatgtagcaaaacatcacattgtgtc ccataaatatatacaattattatgtgaattaaataaaaaaaaattttaaagtcttatctaaatgaaatttctaaccagat tctgaatccatgataccactgaaaccagcacacatgatcgcagtaaaacctcattatacttcctccactatcaccaatac cctttattctctggaacatgaaacattctgttgtgctcatatcatgcaaattatcactagtaggagagcagagagtggaa atgttccaggtataaagacccacaagataaagaagctcagagtcgttagaaacaggagcagatgtacagggtttgcctga ctcacactcaaggttgcataagcaagatttcaaaattaatcctattctggagacctcaacccaatgtacaatgttcctga ctggaaaagaagaactatatttttctgattttttttttcaaatctttaccattagttgccctgtatctccgccttcactt tctgcaggaaactttatttcctacttctgcatgccaagtttctacctctagatctgtttggttcagttgctgagaagcct gacataccaggactgcctgagacaagccacaagctggtgagttgtaggcattttttccattactttctgattcataggct caacgcacctcaaagctggaaatgccgggtctgggtacaccctggggaactgcaaagcctgcacacttgggggaaatgat caagatgagaggcaggggtggggatggcatgtgcaccaggagatgttagagaaaccctgaggaagagcagcgtgcagcag gtgatgggggagagtgggcagcaagcgaggccaggacagccactctgctcagtcaccagtccacacacccaggggctcac tctgcccctctgagcacccaaggacgttaaagagctggaactgttagtctaaatataggaccatccaagctctgaaccaa aatgtgtcccttgcctcaactcaggagatccacagaggcagaagtaaggaatttattttctgaaagatagatttctatca gttctgggtgacatgttctgacacttgaaatgacacctaggacagcacatttcaggcatcttgctcattgttcactgtag tagaagctacatgctagccagttgtaaaaatgaaattaagtaatgtgtgcacagcatttaacatagcatctgagcttcag gagcactcaattaatgaccacagttgtgattctttaggcagatgcatttttttccaactttgatcagaggtcttatttag cttctccagatttcaagaatctggctcagtgatatgaaatacaagacttgtgaaaagtgtcaattgcaagagaaatggaa ggataaagtatacaggtgggtggaaaagaaattcacagtcactgccagaaaaaaaattcttgagaatcaagtcctgatga tgttagggcttatagttcttattataaagagttttatgtactcattcagtgaacatttattggtgcctcctttagccagg tactatcataagagctgaaaataaaagcataatccagtccttgatcttgaggaacatgctgtgtgtagcagataacataa taagtgcttatctagatgcatgcagtgttatgtgataagagtaatatgacagaggatacagattaggcttcacagagaag ggggatttgagcaggaggtattgaagggtgaatagaagctcaccaatcattttgggcagaggggcaaggacctgcaaaac cactgaagcatgaaggaaatggtgagtttagggaaaatgaagagaagatggctgtgactgaagcacaggatttgggattg gagaagggactggaggtgaggctgagaagaggcaaactcagaaaagatgttgtgctgggcagtctggacattatctttga agcccaccacatataagtcatagggctactggaggttttaagctaaaagtgactattcaatttcaacttaagagaagata ggttgagagggaacatggcttgagatgagccatgagcaaaggaaagactacaacaaagccaggagtgaggagtgtgtgaa gcaagaaagtgacagttgaaagcagtgcagaggggatgaatctgagaggcatctatgaggtggaactcaaatgacatgat aataatacagggcatttctctgtgtcagatgctgtcctaagtccttactccattgatcttcacagcaactcagcatagtt aatattttatgcataaagaaatcggcacttgaaggagtaattggccccagattacactgcctataaggattcaaatccag gtttgtttggctccaaaaactggctcctaattttcagaaggagaagcgacccagggcaatgcccaattttgcttcttagg caatggaggaatccacaatcggaaggagttttcagcagtgccccatttggggtgggttgaatttgaggtccctgcatgat acccactttgctcacttcagtgcctaaaactgagtatggttcatagtaggtgttcaataagtgttgatgcagtgaataca tgcatggggagatatgcatcaggcaatgggaaattcaactctaaggcttaggggaaagctggagcttgaagacagagctt tagaaaacagtagcatagaagggagtaggaaccatgagtttagacaatacaattcaggaagaactttgtagcaaggataa agaggcaaaaaattaaagaggtgagagctaagtgtggtgcctggggaatcttaaggtgtgggcacggggaggagatgcca gcaaagaacatgaataaaaagcggtagcacagcccctcccatctggaagccaaaaagaattgtaaatggaggaagttagc agaaggatcaaatacttgaagagggtggaattggaataaaaccagggcatttgaaaaattgggttgtcactgcaatctta acaagagaagttttggcaggatgatggaggcagaaagctgagagaatcatcagttagaacgtttttgacttcagagaaca gaaaatgcagttcataatggctttaaaacaggggcttgtttttctcccagcaatttgagaggccaaggcgggtgcatcag gaggtcaagagaccgagaccatcctggccaacatggtgaatccccatctctactaaaaatacaaaaattagcggggcatg gtggtgcacgcctatagtcccatctactcaggaggctgaggcaggagaatcacttgaacccaggaggtggaggttgcagt gagctgagatcatggccactgcactatagcctggagacacagcgagactccgtctccaaaaaaaaaaaaaaagaaggcag aaggtgaatagttcaagggtgggtttaggactcagtgataataggattctgcctggcttctcatggttctctaggtcttc cattcatggcaccatgccctcactaggcatgctgccagagcaggaggggcaggtggagggttctcttgtgtctgtcttat cagggaagaagagctttctcagaagcccccagcagactcccttttcatattatggtccagcaatgagtcacagacctatg caccacctgcaaaggagccagagaaaacaaacgcccagcgcttttagcctgaaaatgagaatctggtttgctggggaaga taaagggtgtcggaaaatggctgttgggtaaatcattgatgtctgccactaggaatgaaaggcaaatcaggaactggcac acatgctttcagggagatggctgcaagggagagggcaaagactgggaagttgcttatgtggtgccagactatttggaaga tcatggattgcggtgtttgtgttgtgtggtcatcattttgttctttgtttacagaacagagaaagtggattgaacaagga cgcatttccccagtacatccacaacatgctgtccacatctcgttctcggtttatcagaaataccaacgagagcggtgaag aagtcaccaccttttttgattatgattacggtgctccctgtcataaatttgacgtgaagcaaattggggcccaactcctg cctccgctctactcgctggtgttcatctttggttttgtgggcaacatgctggtcgtcctcatcttaataaactgcaaaaa gctgaagtgcttgactgacatttacctgctcaacctggccatctctgatctgctttttcttattactctcccattgtggg ctcactctgctgcaaatgagtgggtctttgggaatgcaatgtgcaaattattcacagggctgtatcacatcggttatttt ggcggaatcttcttcatcatcctcctgacaatcgatagatacctggctattgtccatgctgtgtttgctttaaaagccag gacggtcacctttggggtggtgacaagtgtgatcacctggttggtggctgtgtttgcttctgtcccaggaatcatcttta ctaaatgccagaaagaagattctgtttatgtctgtggcccttattttccacgaggatggaataatttccacacaataatg aggaacattttggggctggtcctgccgctgctcatcatggtcatctgctactcgggaatcctgaaaaccctgcttcggtg tcgaaacgagaagaagaggcatagggcagtgagagtcatcttcaccatcatgattgtttactttctcttctggactccct ataacattgtcattctcctgaacaccttccaggaattcttcggcctgagtaactgtgaaagcaccagtcaactggaccaa gccacgcaggtgacagagactcttgggatgactcactgctgcatcaatcccatcatctatgccttcgttggggagaagtt cagaaggtatctctcggtgttcttccgaaagcacatcaccaagcgcttctgcaaacaatgtccagttttctacagggaga cagtggatggagtgacttcaacaaacacgccttccactggggagcaggaagtctcggctggtttataaaacgaggagcag tttgattgttgtttataaagggagataacaatctgtatataacaacaaacttcaagggtttgttgaacaatagaaacctg taaagcaggtgcccaggaacctcagggctgtgtgtactaatacagactatgtcacccaatgcatatccaacatgtgctca gggaataatccagaaaaactgtgggtagagactttgactctccagaaagctcatctcagctcctgaaaaatgcctcatta ccttgtgctaatcctctttttctagtcttcataatttcttcactcaatctctgattctgtcaatgtcttgaaatcaaggg ccagctggaggtgaagaagagaatgtgacaggcacagatgaatgggagtgagggatagtggggtcagggctgagaggaga aggagggagacatgagcatggctgagcctggacaaagacaaaggtgagcaaagggctcacgcattcagccaggagatgat actggtccttagccccatctgccacgtgtatttaaccttgaagggttcaccaggtcagggagagtttgggaactgcaata acctgggagttttggtggagtccgatgattctcttttgcataagtgcatgacatatttttgctttattacagtttatcta tggcacccatgcaccttacatttgaaatctatgaaatatcatgctccattgttcagatgcttcttaggccacatccccct gtctaaaaattcagaaaatttttgtttataaaagatgcattatctatgatatgctaatatatgtatatgcaatatatata ggctcttgcttgatctctccaggaggtagtgattatgagaagggggtggagaatgatgagttccttcaccaggagcaaag gacggggatcgtgtggaaccactgcagaactatttccggaatcaactaagtggagagagccaggaaggctgcatcagaac ccagtaaagcttcttgtctggatctgagctggtttgttttgtgcttgcttttccctgccttgccactcccctcactcttc tcttttccccacagcctttttcacatagctcttggctgtaggattgccccactccaaaaaccagtgtgtggaggtccagg agtgagaccaggaaagaatgtgaaagtgactacacaaggactcctcgatggtcgtggaaaaggaaagtcaattggcagag cccctgaagccagtcttcaggacaaagaaggagcctagagacagaaatgacagatctctgctttggaaatcacacgtctg gcttcacagatgtgtgattcacagtgtgaatcttggtgtctacgttaccaggcaggaaggctgagaggagagagactcca gctgggttggaaaacagtattttccaaactaccttccagttcctcatttttgaatacaggcatagagttcagactttttt taaatagtaaaaataaaattaaagctgaaaactgcaacttgtaaatgtggtaaagagttagtttgagttactatcatgtc aaacgtgaaaatgctgtattagtcacagagataattctagctttgagcttaagaattttgagcaggtggtatgtttggga gactgctgagtcaacccaatagttgttgattggcaggagttggaagtgtgtgatctgtgggcacattagcctatgtgcat gcagcatctaagtaatgatgtcgtttgaatcacagtatacgctccatcgctgtcatctcagctggatctccattctctca ggcttgctgccaaaagccttttgtgttttgttttgtatcattatgaagtcatgcgtttaatcacattcgagtgtttcagt gcttcgcagatgtccttgatgctcatattgttccctattttgccagtgggaactcctaaatcaaattggcttctaatcaa agcttttaaaccctattggtaaagaatggaaggtggagaagctccctgaagtaagcaaagactttcctcttagtcgagcc aagttaagaatgttcttatgttgcccagtgtgtttctgatctgatgcaagcaagaaacactgggcttctagaaccaggca acttgggaactagactcccaagctggactatggctctactttcaggccacatggctaaagaaggtttcagaaagaagtgg ggacagagcagaactttcaccttcatatatttgtatgatcctaatgaatgcataaaatgttaagttgatggtgatgaaat gtaaatactgtttttaacaactatgatttggaaaataaatcaatgctataactatgttgataaaagatttaaaaacaact ggctgtttttttacactgtggtgtggaagattgtgttgtgttcacaacttttcacttcttcccctgtgtgattacacaca cctgcccttgtggtgtgacttgcagtgcgccctacaggccacacaaccccatgccctccaccactggctctgctgctgga atgtgagcagaagtgacatctgcctcatccaagcagagcctcttgctcagccacaggaaggcccattccagatcacaccc gtcagcccgtgcgccctggtgaatgagaagacacagggagctgcagccacatataacatgagcaagaagtctgtgtttgc tgtgataagccactgagttttaggggttgtttgttaagaagcacaaaaaccgattaagacatgtggtatatagtgacttc atatatagaatctggaaaactatccatttattttcaatcatggaattcaatatgacaagcatcccggagggtctacctat gccagactgggttggaaacagaaagacagatgttaatgccagtgtcctttacacctccaagtccagggccagctgtggag tgggaggggtagagaaggtcctgtgcacagtcacagtgcgctgtgcagagcaggaacagaggcatctgtgaaaagtgctg agagcctggaggacagagtgactaatgcaatgacagtcttgcatcataggaataacagccacagcaggattttattgctg ccaaagaaactgccatttaaaaattgccagccatccgggaggctgaggcaggagaatggcatgaatccaggaggcggagc ttgcagtgagccgagatcgggccactgcactccagcctgggcaacagagccagactccatctcaaaaaaaaaaaaaaatg ccagccatctctctttctaaagtggaatcctcaagtctcgtttattctggggacatttgagtaggctgttcgagttaagc aggtggaagttgatgatccctcatcatcattctgagggatgagtgtctgaagactttttggtaaggaagggtcttggcat agcccaccccatgccacctcccttgatctgtgatatccccagcagctggggaggttggagcattttgcaaagaggccccg aagcctccagaaagtaaaccttcaagagcccatccttccttcctcttttgtttttgctcattatgaaaacttccctgaca aattgaaaaggcttcaggtgagattagcccacaggaaaaaccaccaagggccacccagaggggccacactgtgacagaag gagtatgggctggtgagctgacctctggaagacagtgcatgaattgaggagaagagattggttccaggcatgggaggaat gaggctggaaatttcttcagacattgccacttcggcactctgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtg tgtgtgtgtgtgtaaacagagtcctgtaatgcaaggtccggccttggcagccccagcctggagccacagtgagatgtgag ctgagggttatgctgggaaaaacctctccctcccagcacctgaaaggctctgcaggcccagcagctcagcaagcaagggt aagggcatggactaacatcttatttcatactatcccttataacacatcctaatgtaatcagctcacaatatgaaattatt tcatttctctccagtcattgtttcaatggggccttagggttgactggattctggaggtccctgcctagaggagggggtgc attctgtccctatgtcccctcctgctccatcctccacagcacgtgcctagtggtctaccttgtggggaattcttgtacct ccctcttctaggcatggactagcattgagaagtgggagaggagtgttaggaaaaagggcaaatatagacataccttgtct tattgtgctttacagatattgtttttgttgttgttgttgttgtttacaaattgaaggtttgtggcaaccctgcctcgagc aagtctattggtgctgtttttccaacagcatgtgcttgttttacatctctgtgtcacattttggtaattctcccaatatt tcaaactttgtcattatttctatatctgttatggtaatctgtgatcagtgatctttgatgtcactattgtagttgttttg gggcaccatgaagtgcacccatgtaagatggcaaacaatcaataaatgttgtgtgtgttctgactgctccatggactgcc tgttcctgagacacaataatgtatatataacaattatatatatatatatttataacaattatatatatatatattttttt tttttttttgaggcagagtcgcactctgattgcccaggctggagtgcaatgatgtgatttcagctcactgcaacctctgc ctccccaggctcaggtgattctcccacttcagcctcccaagctgggactacaggtgtgcaccatcacacccggctaattt tttttttgtatttttaggagagacagggttttgccatgttgcccaggctggccttaaactcctagactcaaacaatccac ctgcctcagcttcccaaagggctgggattacaggcatgagccactgtgcccagcccaagacacaataatattgaaattaa gccaattaataaccctacaatggcctctaagtgttcaagtgaagggaaaagtcccacgtctctcactttaaatcaaaatc tagaaatgattaagcttagtaaggaggacatattgaaagtcaaggccaaaagctcacctctgcaccagttagccaaattg cgacttcacaggaaaagttcttgaaggatatttaagctctactccagggaacatgcaaatgaagagaaaacaaagcagcc atattgctaatatggagaaagtttgagtggtctggagaaaagatccaaccagccacaacatttccttaagtcaaagccta atccagagcaagactctaactctcttcaatgctatgaaggcggagagaggtgaggaagctgcagaagaaaagtttgaagc tagcggaggttggtttgtgaggtttaatgaaagacaacatctccataacataaaaatgcaagatgaagcagcaagtgcaa agggagaagctgtggcaagttatccagaaaatctagataagataattgatgaaagtgtctacacgaaacaacagattttc agtgtagacaaaacagtcttatgttggaagaagatgccatccaggactttcacagctagagaggagatgtcaaggcaagc tgcaaagctccacaggacaggctgactctctttttagaggtgaatgcagctgatgactttaagttgaagtaaatgttcat ttactattttgtaaatcctggtgtcattaagaattatgcgaaatctactctatctgtgctccataaatggaacaataaag cctggatgacaacacatctgtttacagcatggtttactgaatatttcaagcccactattgagaactattgctcagaaaaa aagattcctttcaaaatattactgctctgcaccatgtcgatcaagagctgtgttggagatgtacgagaatattcatgttg ttttcatccctgctaacacaaacatccattctgcagtccatggaccaagactttcaagtcttattaagaaatatatttca taaggctattaagaaatagctatatatatatatatatatagccttatatagtttatatagctaccattgatagtgattcc attgatggatctgagcaaagcaaattgaaaagcttctggaaagtagtcattattctagatgccattaggaacatttgtaa ttcatgggaggaggtcaaaataccaacattaacaggagtgtgaaagacattgattccaacccccatagatgactttcagg ggttcacgtcttcagtggaggaagttgctgtagatgtggtggaaacagcaagagaactagaactagaagtggagcctgaa gttgtgactgaattgccgcactctcatgatcaaacttgaacagatgaagagttgcttcttacatatgagcagtgaaagtg gtctcttgagatggaatctcctcctggtgaagatgctgtgaacacggttaaaatgacaacaatcgatttagaatattaca taaatttagttaataaagcagtggcagggtttgagaggattgactccaattttgaaagaagtgggtaaaatgctatcaaa tagcatcacatggtatggagaaatcttttgtgaagggaagagtcgaccaaggtggcaaattgcattgtcatcttatttta agaaattgccacagccacccccagctttagcaaccaccaccctgatcagtaagcagccatcaacatcaaaacaagaccgc catcctcttcagcaaaaacactatgacttgctgaaggctcagatgatggttagcatttttagcaatacaatatttttaat taaggtatgcacattggtttttctgacataatactattgcatacttaatagactacagtataggataaacacaactttta tatgcactgggaaaccaaaaaggttatttttgagatatttgctttactgtggtggtctgaagctgaactcacaatctcac caaggtgtgcctgaacctctttagctaactggccactgccacagtccactctgtgttggtcaagatgccccagagtggca ggcacactgtgtggtcacatccaagggcctagatatggtgggggctccaaatggatctagatatgtgagatctctctttg atttgacttcttccaacccaccattttctgggtgctgggctcatctcacccagaaagtaggacccaatgtgacagttcct gcccagttccctcctgtggtagccacttgacccaggggcactcttgatccttgcagcctcacttacacaccctatctcta cccctattaactctctccaatccccactccccctgctcagcttgtctgctgcccagtgggggccccacccatgctggcct ctccttttgcaagtccccattcctcatatggtttcttcagagcccctttctttggctttgaggagagatgccctcactcg cttccccaccaatcctgcccacttctacaatccattcattatcctaattgcctccgtatacagactggagtgagaggagt tgatgtgatgggtgtggatacagggctggtgctgtcatcttctagtaagccctgggagaggtgtctgagcccaggtgtca gtggttttctttggaactgtgagtgcataacacttctttgccttcagccttaggccatagttgctagttctgggacaacc agaaaagccctacataatctcgtgttatgtgcagagctgagtatagagctccaggtatgatctgactcacttaagatcac agtgagtctattgtattgttgaactgttagcttagacatctgttactgtacctacatggcactagcctcacgcctagaca ccgatctgaaagaaatcccctaaatgcatagagaagacttctcagctgagctaaggggctcccaccaggtttgagcctat ctaatgaatccatgaggtagacagcctgcacatgtccacttggtttgatgaattgcacaaatccctatgggggatgtggt tcatgggctgggaagtgggttaccctgggaaaggtctacaggacagaggcagggatggagacaacagcatggtgagttcc caacccacccacgatgataggtgtctgaggcagaaggtaaagaggctgtcacctggtgggtgtcataagactcaagtgtc attgttgaggcacatgggtaacaaagcgtggcactggatgggggtagattcttcctatttctgtgaggatcagggggact ccctggctctcctgctaaaggtggctctagggacaggaagagtgtacttcttgacagggatgtcagagcactgatggtga caatcagtgtgacactgctcacatgactgaacaaccgagaagagcccgactgtctactgaacaacgggaagagcccgact gtcaatgacggagctctgttaaatatagttaaggctattttgttgaatgaatgaagccagacaggaaagaggacagtatc tttaatccatttatagaagttaaagacaggcttatttaatctctatgaagacagagtggcccttacctctgggtggagca aaaggcaccttctgaagtgatagggatgttccttatcatcttgatccggagtggtagttacatgcatgtatgcatatcaa aactcaccaagctgtaccactaagtgtgttcttcctcaataaaaataataaagaactacacttataaagaattttttaat aatataggaaaatgtctacactataatctttagctaaaaaaaaaaaaaaagaagccgcctacagaatggtatatgcatga gaacaattaatcgaaaagtgcatgggaaaagtcaggattgaaacatcatgttttaaaagacattgttttgatactgtgag aatgtacctaagtttttccttttttctgtttttcccaattttatacaatgagcatgtgttggttttataattagacattt tgtttgtttggtttggttttgagacacagcttgctgtcacccaggttggagtgcaatggcccaatcttggttcactgcaa cctccatctcctgggttcaagagattctcccacttcagcctcctgagtagctgggactataggggcgcaccaccacatcc agctaattttgtgtatttttagtagagatggggtttcaccatgctggccaggttggtctcaaactcctgacctcaagtta tccactcgccttggcttcccaaagtgctgggattataggcatgagccaccgcacttggcctagacatttgtttttaaaaa taaaagattcatttgctctttttacagcccgtctcactgttgactgatattgaccaggagtcaactcaggccccagggat tttcacaacagctgctgtatggcagggtttctgctcactgtgctcatgtagttggcccttgcacccaaagtgaataatta acattctccccatcctgttgacgatgctctgaaaatatggtccagaaatggtgtgagcaaggagacagcaaagcaatgct tggaacataggtgcagtgactagacatggggcagctgtttaaagacaaaaaggccccaaaaaggagggatggcacgaaac accctccaatatgggcatggagtctagagtgacaaagtgatcaaaagttcatttcctatggggtgtccgaatgtacttaa taataaaaagagaacaagagccatgcaaactgagagggacaaagtagaaagagtagcagacaccaagcaactaagtcaca gcatgataagctgctagcttgttgtcattattgtatccagaacaacatttcatttaaatgctgaagaatttcccatgggt ccccactttcttgtgaatccttgggctgaacccccctgtcctgagtggttactagaacacacctctggaccagaaacaca aaagtggagtaacacacactgcaaagctgtgcttccttgtttcagcctgtgaatcctcaccttgtttcccatctagccta tatttttcaaactaacttggccatagaatcatgtagtatttagggtggaagctgccccaggtctagcacgtcatttaaca gatgaggaaatggaagcttgggcagtggaagtatcttgccgaggtcacacagcaagtcagcagcacagcgtgtgtgactc cgagcctgctccgctagcccacattgccctctgggggtgagtatgtcttcacatcctccaataccctaatgacagacaaa cagaacatggcaaagcctcagctctgcatggtgaaagtaagaaccagcaattgccacaaacagaaatacagtgttggtcc ggcagcctccgggggttctgcacaagtggattaccagtgaatacaaggctatctatctttcgaaaaaccaacgttgtatt tatgctattttctataaaattttatattaatttatttgttacctatttttgaactctttcaaaagcacactttatatttc cctgcttaaacagtcccccgagggtgggtgcccaaaaggctctacacttgttatcattccctctccaccacaggcatatt gagtaagtttgtatttgggtttttttaaaacctccactctacagttaagaaaactaaggcacagagcttcaataatttgg tcagagccaagtagcagtaatgaagctggaggttaaacccagcagcatgactgcagttcttaatcaatgccttttgaatt gcacatatgggatgaactagaacattttctcgatgattcgctgtccttgttatgattatgttactgagctctgttgtagc acagacatatgtccctatatggggcggggttgggggtgtcttgatcgctgggctatttctatactgttctggcttttccc aagcagtcatttctttctattctccaagcaccagcaattagctttaccttttcagcttctagtttgctgaaactaatctg ctatagacagagactccggtgaaccaattttattaggatttgatcaaataaactctctctgacaaaggactgctgaaaga gtaactaagagtttgatgtttactgagtgcatagtatgtgctagatgctggccgtggatgcctcatagaatcctcccaac aactcatgaaatgactactgtcattcagcccaatacccagacgagaaagctgagggtaagacaggtttcaagcttggcag tctgactacagaggccactggcttagcccctgggttagtctgcctctgtaggattgggggcacgtaattttgctgtttgg ggtctcatttgccttcttagagatcacaagccaaagctttttattctagagccaaggtcacggaagcccagagggcatct tgtggctcgggagtagctctctgctgtcttctcagctctgctgacaatacttgagattttcagatgtcaccaaccaccaa gagagcttgatatgactgtatatagtatagtcataaagaacctgaacttgaccatatacttatgtcatgtggaaaatttc tcatagcttcagatagattatatctggagtgaagaatcctgccacctatgtatctggcatagtgtgagtcctcataaatg cttactggtttgaagggcaacaaaatagtgaacagagtgaaaatccccactaagatcctgggtccagaaaaagatgggaa acctgtttagctcacccgtgagcccatagttaaaactctttagacaacaggttttttccgtttacagagaacaataatat tgggtggtgagcatctgtgtgggggttggggtgggataggggatacggggagagtggagaaaaagggggcacagggttaa tgtgaagtccaggatccccctctacatttaaagttggtttaagttggctttaattaatagcaactcttaagataatcaga attttcttaaccttttagccttactgttgaaaagccctgtgatcttgtacaaatcatttgcttcttggatagtaatttct tttactaaaatgtgggcttttgactagatgaatgtaaatgttcttctagctctgatatcctttattctttatattttcta acagattctgtgtagtgggatgagcagagaacaaaaacaaaataatccagtgagaaaagcccgtaaataaactttcagac cagagatctattctctagcttattttaagctcaacttaaaaggaagaactgttctctgattcttttcgccttcaatacac ttaatgatttaactccaccctccttcaaaagaaacagcatttcctacttttatactgtctat tgattgatttgcacagc tcatctggccagaagagctgagacatccgttcccctacaagaaactctccccggtaagtaacctctcagctgcttggcct gttagttagcttctgagatgagtaaaagactttacaggaaacccatagaagacatttggcaaacaccaagtgctcataca attatcttaaaatataatctttaagataaggaaagggtcacagtttggaatgagtttcagacggttataacatcaaagat acaaaacatgattgtgagtgaaagactttaaagggagcaatagtattttaataactaacaatccttacctctcaaaagaa agatttgcagagagatgagtcttagctgaaatcttgaaatcttatcttctgctaaggagaactaaaccctctccagtgag atgccttctgaatatgtgcccacaagaagttgtgtctaagtctggttctcttttttctttttcctccagacaagagggaa gcctaaaaatggtcaaaattaatattaaattacaaacgccaaataaaattttcctctaatatatcagtttcatggcacag ttagtatataattctttatggttcaaaattaaaaatgagcttttctaggggcttctctcagctgcctagtctaaggtgca gggagtttgagactcacagggtttaataagagaaaattctcagctagagcagctgaacttaaatagactaggcaagacag ctggttataagactaaactacccagaatgcatgacattcatctgtggtggcagacgaaacattttttattatattatttc ttgggtatgtatgacaactcttaattgtggcaactcaaactacaaacacaaacttcacagaaaatgtgaggattttacaa ttggctgttgtcatctatgaccttccctgggacttgggcacccggccatttcactctgactacatcatgtcaccaaacat ctgatggtcttgccttttaattctctttttgaggactgagagggagggtagcatggtagttaagagtgcaggcttcccgc attcaaaatcggttgcttactagctgtgtggctttgagcaagttactcaccctctctgtgcttcaaggtccttgtctgca aaatgtgaaaaatatttcctgcctcataaggttgccctaaggattaaatgaatgaatgggtatgatgcttagaacagtga ttggcatccagtatgtgccctcgaggcctcttaattattactggcttgctcatagtgcatgttctttgtgggctaactct agcgtcaataaaaatgttaagactgagttgcagctgggcatggtggctcatgcctgtaatcccagcattctaggaggctg aggcaggaggatcgcttgagcccaggagttcgagaccagcctgggcaacatagtgtgatcttgtatctataaaaataaac aaaattagcttggtgtggtggcgcctgtagtccccagccacttggaggggtgaggtgagaggattgcttgagcccgggat gatccaggctgcagtgagccatgatcgtgccactgcactccagcctgggcgacagagtgagaccctgtctcacaacaaca acagcaacaaaaaggctgagctgcaccatgcttgacccagtttcttaaaattgttgtcaaagcttcattcactccatggt gctatagagcacaagattttatttggtgagatggtgctttcatgaattcccccaacagagccaagctctccatctagtgg acagggaagctagcagcaaaccttcccttcactacaaaacttcattgcttggccaaaaagagagttaattcaatgtagac atctatgtaggcaattaaaaacctattgatgtataaaacagtttgcattcatggagggcaactaaatacattctaggact ttataaaagatcactttttatttatgcacagggtggaacaagatggattatcaagtgtcaagtccaatctatgacatcaa ttattatacatcggagccctgccaaaaaatcaatgtgaagcaaatcgcagcccgcctcctgcctccgctctactcactgg tgttcatctttggttttgtgggcaacatgctggtcatcctcatcctgataaactgcaaaaggctgaagagcatgactgac atctacctgctcaacctggccatctctgacctgtttttccttcttactgtccccttctgggctcactatgctgccgccca gtgggactttggaaatacaatgtgtcaactcttgacagggctctattttataggcttcttctctggaatcttcttcatca tcctcctgacaatcgataggtacctggctgtcgtccatgctgtgtttgctttaaaagccaggacggtcacctttggggtg gtgacaagtgtgatcacttgggtggtggctgtgtttgcgtctctcccaggaatcatctttaccagatctcaaaaagaagg tcttcattacacctgcagctctcattttccatacagtcagtatcaattctggaagaatttccagacattaaagatagtca tcttggggctggtcctgccgctgcttgtcatggtcatctgctactcgggaatcctaaaaactctgcttcggtgtcgaaat gagaagaagaggcacagggctgtgaggcttatcttcaccatcatgattgtttattttctcttctgggctccctacaacat tgtccttctcctgaacaccttccaggaattctttggcctgaataattgcagtagctctaacaggttggaccaagctatgc aggtgacagagactcttgggatgacgcactgctgcatcaaccccatcatctatgcctttgtcggggagaagttcagaaac tacctcttagtcttcttccaaaagcacattgccaaacgcttctgcaaatgctgttctattttccagcaagaggctcccga gcgagcaagctcagtttacacccgatccactggggagcaggaaatatctgtgggcttgtgacacggactcaagtgggctg gtgacccagtcagagttgtgcacatggcttagttttcatacacagcctgggctgggggtggggtgggagaggtctttttt aaaaggaagttactgttatagagggtctaagat catccatttatttggcatctgtttaaagtagattagatcttttaag cccatcaattatagaaagccaaatcaaaatatgttgatgaaaaatagcaacctttttatctccccttcacatgcatcaag ttattgacaaactctcccttcactccgaaagttccttatgtatatttaaaagaaagcctcagagaattgctgattcttga gtttagtgatctgaacagaaataccaaaattatttcagaaatgtacaactttttacctagtacaaggcaacatataggtt gtaaatgtgtttaaaacaggtctttgtcttgctatggggagaaaagacatgaatatgattagtaaagaaatgacactttt catgtgtgatttcccctccaaggtatggttaataagtttcactgacttagaaccaggcgagagacttgtggcctgggaga gctggggaagcttcttaaatgagaaggaatttgagttggatcatctattgctggcaaagacagaagcctcactgcaagca ctgcatgggcaagcttggctgtagaaggagacagagctggttgggaagacatggggaggaaggacaaggctagatcatga agaaccttgacggcattgctccgtctaagtcatgagctgagcagggagatcctggttggtgttgcagaaggtttactctg tggccaaaggagggtcaggaaggatgagcatttagggcaaggagaccaccaacagccctcaggtcagggtgaggatggcc tctgctaagctcaaggcgtgaggatgggaaggagggaggtattcgtaaggatgggaaggagggaggtattcgtgcagcat atgaggatgcagagtcagcagaactggggtggatttggtttggaagtgagggtcagagaggagtcagagagaatccctag tcttcaagcagattggagaaacccttgaaaagacatcaagcacagaaggaggaggaggaggtttaggtcaagaagaagat ggattggtgtaaaaggatgggtctggtttgcagagcttgaacacagtctcacccagactccaggctgtctttcactgaat gcttctgacttcatagatttccttcccatcccagctgaaatactgaggggtctccaggaggagactagatttatgaatac acgaggtatgaggtctaggaacatacttcagctcacacatgagatctaggtgaggattgattacctagtagtcatttcat gggttgttgggaggattctatgaggcaaccacaggcagcatttagcacatactacacattcaataagcatcaaactctta gttactcattcagggatagcactgagcaaagcattgagcaaaggggtcccatagaggtgagggaagcctgaaaaactaag atgctgcctgcccagtgcacacaagtgtaggtatcattttctgcatttaaccgtcaataggcaaaggggggaagggacat attcatttggaaataagctgccttgagccttaaaacccacaaaagtacaatttaccagcctccgtatttcagactgaatg ggggtggggggggcgccttaggtacttattccagatgccttctccagacaaaccagaagcaacagaaaaaatcgtctctc cctccctttgaaatgaatataccccttagtgtttgggtatattcatttcaaagggagagagagaggtttttttctgttct ttctcatatgattgtgcacatacttgagactgttttgaatttgggggatggctaaaaccatcatagtacaggtaaggtga gggaatagtaagtggtgagaactactcagggaatgaaggtgtcagaataataagaggtgctactgactttctcagcctct gaatatgaacggtgagcattgtggctgtcagcaggaagcaacgaagggaaatgtctttccttttgctcttaagttgtgga gagtgcaacagtagcataggaccctaccctctgggccaagtcaaagacattctgacatcttagtatttgcatattcttat gtatgtgaaagttacaaattgcttgaaagaaaatatgcatctaataaaaaacaccttctaaaataattcattatattctt gctctttcagtcaagtgtacatttagagaatagcacataaaactgccagagcattttataagcagctgttttcttcctta gtgtgtgtgcatgtgtgtgtgatgtatacaaagagagagataattgtatttttgtattttcttttaaataatttttaaaa ttgacccttttcctgagacaaattgccagaatagtttgtatttagagatggtacctctaagagtaaggttgctggttgct gagcaattgacttgaaaacttttaaaattcaaattttaattccactactcaaaagaattgccatgttttaaaaaagagaa ttggtgccataagttagttgtctatgtttgaaaatgaagaagatatgcaacgtcatggcctggtcacttacccgcagccc tgagttgtaggcacatcatatgtgagaatgaggatgcttttctttcatttaaaatccctccccaaaacttggctctaatt gcagtcatgacaatcatgtacatttggatttatgtgcacgagtctcttaccctgagagaggacaggtgctacaggtggag gggacccgtctgggtcacgttcacattttgaacatgctggttttcagtcactgcacactcatctcccagcgcaggtcatg ggcagcagatgcaaaagctgcccgtggtcctatttggaggtgcatgaaatgagcagaagacagaatagcttgatctgact agaagggcagcttgtccctaccaagacttgaaggattgcctttcatctgttagggtaaaaggtagaatgaaccaaggaag ggcaggagggggctggggttagggtagaaggaaggggccatggagaagggagatccatcccataggaggaaggcagtgcg gcagggaggtttgaaggtatcagcttttgtggctgacatacatgcagtcatgtcaattgctcgtttttccttttccatct tattaaatgtcttccaatgttagcacgaagaaaagctatttgcagtgttgccagcctttccagagcccgtccccattacc tccccaggcccatgcctttactccttggagtttcaactcacgaccttcaggatctgactttattcaccaactctggggtg aacgtaccttctgtctccacccagaggtctctatcaaagaggagattgcatgccatggataaagtcaaagtagaggtgac tgtccttaggaagagtaatgtgaaaattcataaactgggattctgtttacattttgtactccaggggttcttagtttaaa tcgctctgaataaattaagatgcaatggcatttcaactgttatgattaaatttacaaatcatttattttctatcacgggg agagatagagctccaaatgcaaacataactgctcaagtgttaacacttataatgaaaacataagaattaccaccaactac cctgggggctagaagcagaaatgtgaaccagaaaacaaatcatgaactttcctttttttttttgagatggagtctcgctc tgttgcccaggctggagtgcaatggtgcgatctcggctcactgcaaccactgcctcccgggttcaagcaattctcctgcc tcagcctcctgagtagctgggactacaggcatgcaccaccacgcctgggtaattttttgtatttttagtagagacagggt ttcaccgtattagccaggatgctctcgatctcctgacctcgtgatctgcccgcctcggcctcccaccgaagtgctgggat tacaggcatgagccactgtgcccggccaacaaatcatgaactttctaactgcagttccttgtagcttgttaacacatcca cttacttattgtcagagtacgtggagattttccacaaccctcggggataaggctgaacagaagaggcaaaaacgtgaaaa catttcgatagctcctatactttgaaataaaattcactgtaaaagttgcttgtatttttccaaaacagagtcaaccctta atatttaagattctgtatacaaatacatatttttatataattaatatatattgtcatatgacatatatctttatattaat atgcatgcatataatatatatttccttcctaattttctataagcaattttacaagactgacttctatttgcctccttatt gttactacgtggtttgataatccgttttgtgtcattgtgattctgtcatgttttggggacttatttttgtttctctgggt ggtcactagtttttttaaagcattcatggaagagtgtgaatcttttacaagctaggaagccatggcaagccttgggtcat actgcccccgcgaggccacattggcaaaccagcaagggtgttcaacttccagacttggccatggagaagacatacgagga ggcttttcacattcagctctttaatgtttgtctctgccggcaccatcccagttgtgaataagaggtatttccacagcggc tcagggtaggtagtgcacagctcacattcatcatttctgaaaaccgagaggagtctccattcggggtacaggttgatgcc tgtcgtggaatgaaggttccaacacccagaccaatctctgcagtgtgctgctctcatgagcttgcaacaagatcagaaaa tgttttgtgactaagcatttttcatattgcataaaatgcttcaagctcctcccttgtttctctctataatcctgtatatc tgatgattgtgggtaccaagtgtttgaaataatcaaatgtgatttgatgttggtaaatttctttttttttttttttttac ttctattttttttattatactttaagttttagggtacatgtgcacattgtgcaggttagttacatatgtatacatgtgcc atgctggtgcactgcacccactaactcgtcatctagcattaggtatatctcccaatgctatccctcccccctccccccac cccaccacagtccccaaagtgtgatattccccttcctatgtccatgtgatctcattgttcaattcccacctatgagtgag aatatgcggtgtttggttttttgttcttgcgatagtttactgagaatgatggtttccaatttcatccatgtccctacaaa ggacatgaacatagcaaagacttggaaccaacccaaatgtccaacaatgatagactggattaagaaaatgtggcacatat acaccatggtaaatttctttatcattcgcactctcctttctctattattgttattgtaactgaaccgcagattagtcact cattgcttgcagaatccaattaacaagagcgaggtcagatataaagaaaatgatttattccaaacctccttcagggaaga ggtgcagcctcctgcctctaaatgcactgcttcgccaggcgtggtggctcacacctgtaatcccagcactttgggagacc gaggagggcagatcacttaaggtcaggagttcaagaccggcctggccaatatagtgaaacccctgcctctactaaaaata caaaaaattagccagacgtggtggcgggtgcttgtaatcccagctactcgggaggctgaggcaggagaatcgcttgaacc tgggaggtggaagttgcagtgagctgacatctagccactgcactccagcctgggtgacagagtgagactctgtctcaaaa taaataaataaataaataaataaataaatagtaaatgcactgctttgcttttggagcagaaagcaggcactttgaaaagg caggggaggaagtgagcaagggcagggggtctgcacactggcatggtgcctgatctatccaggcagttgaattggcactt tcataggcagaaataagttgaaaaagtggcctaaaactctctaggtgggagtggatagtgggcatgccttcaacctgcct ttctggagggtgagttccatggcaaccccctgaagggtgagagttccatggagatcatgctttggtctgtaaatcagctg ttaactctctagaaagttctgtcttggagcatatagttagatgaacttgccctgtaaagaatgtctggtgaaggggaagt aaaaggtgagatttgcatttctaaagggctaagtagaacgtggggtacaagaggaaaggagaaaagagaaaataatttaa aaaataattgtaacttattcccttttacttagaaaaaagggaatactcagttacattatcacctcgtttacatcaaaccc tcttatggaatcctatggtttgaaaacaaaaaggttgttgaggaccagtgagcccaacccctttgctttataaatgaaga gcattgcctgccctaagccccagagactctgatgtcgtgggtctggagtgggctccaacagcggcatgttttgatggtgc ttcccagtggcacgccagcgatgagcctttgagtagggaaagtaggagcactcgtgactcccttcacgatcagcacctgt gtgctaataaattcacaaaagccaacatattggagtcactcagggagttttacaaatagtgaggttaaatccaacctcaa atagttctgattcgatctgcctgcattgctgccctgtggttccccactgtagaagctccccaggtgattctaagtgtagc caagtctgagaaatactgcctaaagcctgttggactgacagcaagggctgttgtctgagcaagactttgcctggcctggg gtggcatgtgcaccaggaagagtctcaactttcataacagaacattccccaagctggtttttttaaagcatgtgaatcta gacttcattggcaataccaaagatctgtatttgaggctccaagtatttcactttcatttttggttttgggttatgttttc acccttcctttccaagtgaaaagtaaacagaagtgggatgtctggcgcccatgctgagcttggcaacttcaaattcaata gagaagaagtctcttgtatagaaaagggcctgtctgagatgtttctcaaataaatatagattttgcttatgtggctaaag gattcttctccccccatttcctt tccctgcagtgagccatccttcttaactctttccatgaaagcattattcctgaaga actgggaactcatgccagccctgatcaggcaatgataattctgcagagaattagaatttagatttaaattgtcaactctt atacatcctggcatatggtttaaacacatgtacacacacacaaacacctcctactatttactgaagagcagatatctgat aacttaatctttttggttttgagtcaagacaattcctccttttgaaactgcataccgctgaatataataaaatgtaatta agattaaaaataagaaactaatgggagaatttcaatattgtctctgttcactttaaaattcctctacttaggtttactgc cattaccaaagactattcaaaaatcctttttaggagaatcctaatggtttcctgacatataatcaaataaggactctgtt gattggctaactcaatcttcctgtgccaaaaagcagagcccagcagagaagagggcagggacttgaaagtcagactgact cgagttccagccttggggctgtgggagcttgggcaagtgacttaacgtctctggctctcaggatctaaaaggatttccag tagtaatttggggtgttactgatacaggagctaaaaagaaattatttaggtggttagtgagggtcagagagtcctcggta agatttgccttttaacaaaaagcagccccaaaatcatttgtttgctaacaaagagaagcctgtaaaattgagctgcagac atagataagcaagctggaagcttgcacgggtgaatgccggcagctgtgccaataggaaaaggctatctgggggccaggca tgttcaacatggattctccatcttcccttttctttgtcaaccaagtgtacagtaaaggaacaggcaacatggcacgggcc aggtagagaacccttctgcataataaaagattagggtgagatggccagcttcttcccgtgctatgtaaatggcatacctg gtccaaccagtcttttgggccctgtgtaaatcagacaccgcctcctcaagttagtctataaaaccccatgcattttaccg tgaaactgggagatccactcggaaccccctcctgcacgagagaccttttctcttttgcctattacacttccgctcttaaa ctcactgctcatgtgttagcatccttgatttccttggcatgaggcaatgaaccttgtgtattaccccatacaaatgatgc tgcttcattactaatagcaacctgacagggttgtgttggggtataaattatctagaccagggagatccaatataattttt ttgtaatgacgggaatgctttgtatctgcatcatccaaaatggtagccaccaggccagggtgaaatgtggccagtgtgac tgaggaactgaatgttttccatgatttaatttaaatgtggccaatggctactgtaggagacagtgtgagtctggcatatt ataaataataaatattaatataatttgaactttggcatcagtgtttcctagatttgaattactatgcaagttgcttactg tttccaagcctcagctttctaatctgtaattggggctaataatagtatctgccttacaggtttgttcagaggataaatga gaaattgcatgttgagggcttaacacagtgcctggcacataaaagctctggtaacagttagccactttaataatttgcta ataatggctatttcttcttcagattaggatgtgctcccccaaacagtgcacttagacatagcgggcaatccagctcactc tctgcagtgagagagaagcactggccgaccagagtcagccaggggctcatgggtatgaaatcaacagcatgattttgtaa gtaatggatggaaagggcctcacaactttatggcactgtgttcaatttgcttggtcttctgtagctccttttgaaagcct tttagggtggattaacctgctaccaataattctggtcagatgtagactccatagctcaaagcaaactgagagagtgaggg cagcaggccaattccccaccccttccttctggactctgacagaagcttacactcaaggaagagcaagtaggaattaacgt gttaagagctaggtaagcaaaacccaatgagaagttctggcaaagccccatgggcaggggtggcttaggcacaggaaaca agtaggatttcataccacgcgcctcagtctacttccggggccctcatcctcagctgtgcctatgcaaaggagagcaacca ataaaccccaccgccactctcctactgtggaggccagggatggccaggggtaagagagggatgggaagtgtttcctccag ccgtcctctgagaaggagaggaaactgggcagagcttctgtcctccttcaagcagaaacagaaacaaaagaaacccctaa gggggttcttacttcccctctagttcagttgtgcactaaccatctgcagctcaacattcagcattcattcattgattcag caaacattgaaggagggccagctatgtgccagatgccaactcatgccatgaaagagagtccctgtccttatgaaattcac tatttagagagaaaagcaagcaaaaaggcaaagtttgaaaagtactgttgaagtggcatcattgtctggggtgaatacct gaggtttgtggtctcacgccaagggaatcaaggactcaggcacacaagaagtgagtttaagagcagaggtttaataggca aaagaaagagaaaaaagaatagctctcttgcctgcacagagagaggggcacctgagtggatcttcctgttttgtggtgaa atgcaaggcattttatagacgagcttgaggaagtggtgtctgatttacttaggacccgagagattggtcagaccaggtgt gatgtttacatagcatacaaagaagctggccatcccatcctaatcttttattacgcagacggggtctatacctggctggt gccatgttgtctgttccttactgtacacgtggttgacaaagaaaagggaagatgaagaatccatgttgaacatgcctggc ccccagatagtcttttcctattggcacagctgccggcattcactcttgcaagcttccagattgcttatctatgtctgcag cccaattttacaggttgctctttgctagaaaagaaatgatttgggggctgcttttcattaaaaggaaaaccttaccaagg ttaaaaagaaaaaaatttctttttaatgcctatgttactgtgaacagtgtcgggataaggctctgagagccagatgagga tgagttatccaatccaaggatgggggtctggaggaaaaaatcctagagagcattgctgcagttgaataaggattagttag aagctactgagtggagcataggagtaggaactcttatgcaaatgtgcagaggtgaaataaagcaaggtatagtccaggtg cctaaagtagcacagctgacttgagatagatgatagataggtagatagatggatagggtacatagatgatagatagatag atagatagatagatagatagatagatagatagacagacagacagacactggtgtgagtgtgggtgtgtgtgtctggctgc gtgcatgcattcctcctgcaggagatcaggagcagtgggcagtatggagtgacaagaagattgggaggtactccttctag ccctcccctctgctctgccctccactggagcagaagcaaagcatatggtgaaggggaacaaggagtctccccagcacagt acccgagtgcattagctatttatcactccacagtccccattcacgtgttaattcagcatttattgaatgcttactgtttg caatgtctatgtcaagctgtcaagtgtagtttttattctacaggccacaggcaccccctaactgtgttaaacaagatggt agtattgagacaggaataataagggtggtcacaggagaatggaagattccaggcagcagtttgactagtaaaaaaggaaa ctgttgaaatagctgcataatccaggggtcaataagaacctgagaaccagggtgtgagccaaggctggttaaaagcaact ggatccaatatggtgctgagtttctcctaggttttgcctggaacctcattatatgctcaataacataccaaatcacacac ccaccagggccattccatttcctggaacactcatgtttggtgtaaaaatgggtggcaccacagctctgagaaatctttac ctttttcaggaaacttcatgaatattccatcctttggttaaagaaacccataatgtagaagccccaaaccctactgggcg caactctctctctcttgagtatgcctgcacttccctttattatttatttatttatttattatttatttatttatttttta gatggagtctggctctgtcacccaggctggagtgcagtggcgcagtctcagctcactgcaagctctgcctccagggttca ggccattctcctgcctcagcctcctgagcagcagggactacaggcgcccaccacaacgcctagctaattttttgtatttt cagtagagatggggtttcaccatattttattttatttttgagacagggtctcactttgttggctcgctgcaacctctgcc tcccaggctcaagcaatcctccaacctcagccccccaagtagctgggaggacagacgtgcaccaccacacctggctaata ttttgtatttttttttgtagagacagggtcttgccatgttccccaggctggtcttgaactcctggactcaggtgatcagc ctgcctccaccttccaaagtgctaggattacaggaatgagccaccccacccgaccacactcccatttcttgagtgtgtgc attttgctctgcaataaatctctctactttcacttttctctgactcgtccttgaattccttcttgtgacagcgtcaacag cctggacaccaggtgcagtcaacgtctcaccagtgtttagggacctcccctaatccactggtatcagcatgatcagactt gctttttcagaaaaagccttctgtccatagaccaaagggaagtgactcagagaaggggcaggaggaatcacaagctccct gcctgaccaggcctggactatggcagagacagtgagatggtgagaaagcaagggtagacagccagccaaatccagaatat agaaagttctacaggaaaaggtggggccaaggtgggacagggggaaaggaattgttgcacattaacagtgcaatgcagag cactggtcttgtttatgtccaggttagaacaaaccaatgagaaagcacatctttgagacaactggagaaatttgaacact gactagatataatattatgttaattatgctttaatttggggtacaataatgcttttgtagctatttctaaagagtcctta tctcttaaggatacactctaaaatactagtggattaagttatatgatgtttagactctttttaaaataatccagtggggt gagaggcagagggaagggagaggagcatagaggaaacagtgttggccatatgtttgtaattgttaaaactgagtgatggg aatatggagatttaacatattaatactattttctgcccatgtaatatttgaatattttcataataaaattgagagagaga taaagaaagaaaagagaaaagaagagaagagagaagagataagggaagtggaggaaaaagagctttcttcaaggaccatt gtggtggacacaaatgaaagatacccccttcctactatgaattctaggtgtgtactacccaagatgagtcaatcggatcc tagcttccagaaatcgtgagcatgatgcagccctacagacgcagtgccctggaaaggagacccatgaccatccaaggaag atgtcccatcacagaactgccctgggtcatgtgttttccaagtccacatgtccggtagttccttctttcctatgaccaat gccaccagtcttccagcactgtcctttattgctaggcaaacctgagccatcctcttcttcttgcaacttgtgcctgaagt aacatggacacaaagtccccacttttcccacattctcagaatgaagtagttctccctccacactttaggtgctagaggca agtggattgcttgagctcaagagttcaagaccagcctgagcaacatggcaaaaccccgtctctacaaaaaatacaaaaat taactgggggtggtggtgtgcacctgcagtcccagctactcaggaggcagagaaggaggatttcttgagccctgaaggtg gttgtgttacgtgcattcatgttaagagaccaccaaacaggctttgtgtgagcaattaagctttttaatcatgtgggtgc aggcagactgagtctgaaaaaagagtcagcaaagggagatagggatggggcggttttataggatttgtgtaggtagtgga aaattacagttaaagggggttgtcctcttgcgggtacaggcgggggtcacaaggtgctcagtggggagctcctgagattt attgtccaggagaaggaatgtcacaaggtcaactgatcagttagggtggggcaggaacaaattacaatggtggaatgtca tcagttaaggcaggaactgggtattttcacttctttgtggttcttcagttgcttcaggccatctggatgtataagcgcag gtcacaggggatatgatggcttagctcgggctcagaggcctgacattcctgtcttcttatattaataagaaaaacaaaac aaaatagtgatgaaatgttggggcagcgaaaatttttgggggtggtatggagagataatgggtgatgtttctcagggctg cttcaagcaggattaggggtgacacaggaacctagagagtgagagagattaaactgaagaaagattttgtggtaaggggt gatattgtggggttgttagaaagagcaattctcatatagaatgattggtaatggcctggatgcagttttgtatgaattga gaaactaaacggaagacacaaggtctgaataagagaaggagaaaaacaggcattaaaggactaagaactgggaggaccca ggacatccaattagagagtgcccaagggggttcagcataattatttgcttggttggtgagtttttggtctccatccttga gttttttttatgttgtcatatgccaggccagattgatttaggtaaaaacaacactcttcatttaaaaatatacagagttc tcctttctcagcagtgagtaagtcaaggcctcagcagttttggaggaaagagaaatgcaaaggaagcaattgtttgttaa gaaggattagaaatggctaggagagagtgagtgagattgatagtgtggtggagatagctgaggagaggtagagggtggca taagaatgggaacgagaataagagtgagtataaaagtaaagaatagaacttcatcagggtgaaagtattggagggtgccc tgtcagcaaagatcatctgtccactccaagagggagtcaagagtggcggattggggatagtaccaggagatatccactat gatggtttggaggaaaagtgtaaactggcagtgtaaacaggggcagggcatttatgagtcattgagaatggtgaatagga gtatgactagacagaagatagtggagatgacaaattttgggggcacagtccaaatagtgggggtgactgcgtagagctct gttgcaaaaagtagggtaaggataaatagacttaatagaatgaagagatgtattaggctcataagggttattattgttct tcagaaatgcgagtgagtttaagggaagtaggggtgagtacttgcgacttccagaaggaagaggagagatcaggctggct gtctgatgggcacagctttattctggaacagtgaatccaatggggagggtcgtgcagacggatggcagttggggtgctat aaatgaccaggtagggtccagtccatcaaagctgtagagtgtgaggggtcagacttgacaaggactgattgcccagctaa ggtatcttcacatggctgggagtttggaggaggcaagagaagattagcagcctggcgaatttcctgtctagcctgctgga ggactggaagataaaggcaacaggtcgtgggcctggatcctgtgtgaggactctagcagcacagccttgtatttcagctg tgtgtaaggaaaaaggatgggacgagtcggggagtgctagtgtgggagctgtctccaggtcctttttgagagagtgaaag gaagaatggggaaaagacttatggtctatgggattagttaaattaccctttgtgagctagtaaagtggtttgattaggat agcaaagcccggtatccaaagttggaaatatccaacaatgcctaagaaggaagggagttgttgtttggtggtgggggttg gggtctgggagattaactgaacagagtctgcaggaagggtatgtgtatgttgatggagcattataccaagataggtaatg ctaggggaagaaatttgtgcctcagagggcaatactttgtacccctttgagtaaagatgttgaagaagcaggctagtgtc ctgctgggaagattggtaagaggggctgcaaagaagaagatcatcaacatattgaataaggtgggaggtagatgggtgaa aagaaagcagatcatgagaaagggcctggccaaagtaatgtgggctgtccctgaagccttggggtagaaaaatccaggtg agttgttgggactggtgggtgtcagagtcagtccaagtaaggcaaaaagaggctgggaggagggatgcaaggggatagta aagaaggcatctttgaggtcgataacagaatagagttgtggaagggtgtattgaagataggagggtgtacgggtttggca ctataggatggatgggaaggacgatttgatcaacaagacgaagatcctgaacaaacctgtaagacttgtccggtttctgg acgggtaggataggggagttgtaaggagaatttgtaggctttaagaggccatgttgaaacaggcaggtgataacaggctt taacccttttaaagcctgctgtgggatgggatattggcattgagcggggtaagggtgattacattttaatgggatgataa ggggtgcatgatcggttgccaaggtaggagtagaggtttcttatacttgtggattaaggtggggagatacaaggggagga tgtgaaacaggtcttgagttgggtaaaagtgcagcaaagagatgtggctgcagcccaggaatactcagggaagcagataa tttggttaaaatgtctcagcctattaaggaagctggacaggtggggataactaaaaaagtgcataaaagaatgttgtcca agttggcaccagagtgggggagttttaagcggtttagaagcctcgccgacaatacccacaacagttatggaggcaaggga aacaggcccttgaaaagaaagtaatgtggagtgggtagcctccgtattgattaagaaggggacagacttaccctccactg taagagttacccaaagcatctgtgatggtccaggaggcttctgaggtgatcaggcagtgtcagtcttcagctgctaagct gagaagatctgggaaggagtcagtcagagagccttgggccagagttccaggggctctgggagtggttgccaggcaagttg aacagtctgatttccagtggggtctcgcacagatgggacattccttggcccagtggccagatttccggcacttgaaggaa gatcctgggggaggaggtcctggagaaatgcctggcccctgcagtttaggtgttttgaagttcttgtgtgctggagatgt ggctggggtttctcttacagcggaggcaagtaattgcaactcagaaatatgttgtcacttggctgcctcttttctattat tgtacaccttaaggcgagggtaattaaatcctgttgtggggtttgagggctggaatctaatttttggagctttttctaat gtcaggagcagattgggtaataaaatgcatattgagaataagacggccttctggcacctctgggtctagagaggtaaagt gtctaagggttgttgccaaacaggccatggactcagctgggttttcatatttgatgaaaaagagcctaaacgctaactga tttgggagaggtcagctaaagaaaaaggagcattaaccttgactatgcctttagctctagccacctctctaagaggaaat tgttgggccggtgggggagggctagttgtggaacgaaactgtaagccagaccaggtgtgaggagagaaggtgaccaaagg tttatagggtaggggagcagaggctggggaagaattgggacctggctaggcctagcgaggaacagcctggggaggagggg agaaatcagatgggtccgtagaaaaggaggattcaaaggactcagagcttggggtggagactgaaggaacagacaggaga gaaagaggaaagatttgggatgagtcacattgggagcagagactagagagggactgatgtgtaaagaatgcctggacgtc aggcacctcagaccatttgcccattttacgacaaaaattatctagatcttgtaggatggataaatcgaaagtgtcattct ctggccacttggaactattgtcaagtttgtattggggccaagcagtattacagaagaaaataagatgtttaggtttttaa aagagtgcataaaagaatgttgtccaagtccatgcccttcttaatcaatatgggagctacccactccacattaccttctt ttcaagggcctgtttcccttgcctccataactgttgtgggtattgatggccaggcttataagccccttaaaattacccca ctctggtgccaacttggagaggtcaggtgttagtcaaaggtgttttaagttttaagaacacaggctaagggagaagaagg gggaatgaagcgtggaaggttgcccatagtgaaagaggtaagtttaaagagaaaggtagagacatggagaaggggggagg tgagcagccctgggctgtcatgtgggttagcagccaaagctggtgtcccagcaattgacttaccaccaagggaatgtggg tgaatgaccaaggcaggcatccccccggtgatcagacaccaaatggaatgtgggtgaaagatcaaggtaggtgtccccat gatgatcagacaccaaaggaaggctgtcttcccaaatccatgatccatgttggagtttttgagttcatggataaaatgtg tctcctttgtctctactagagaggaaaaagaactggaatttgaaggacagggagattgaagggtagggagagaggctgaa gaagagagtgaggagaccgcttacccggtttgaaattggtgagatgttccttgggctggtctgaggacctgaggtcgtag gtggatcttctcatggagtgagggtgaggagaggggaccaatctcccgaaggagtcaccctgtccggggtcttcggcacc aaatgttatgcgcatccatatgaagagaccaccaaacaggctttgtgtgagcaataaagctttttaatcatgtgggtgca ggcagactgagtctgaaaaaggagtcagcaatgggagttagggttggggtggttctataggatttgggtaggtaatggaa aattacagttaaagggggttgtcctcttgcaggcaagggcaggggtcacaaggtgctcggtggggagttcctgagactca ctgtccagaaggaatgtcacaaggtcaattgatcagttggggtggggcaggaacaaattacaatggtggaatgtcatcag ttaaggcaggagcggcctattttcacttcttttgtggttcttcagttgcttcaggcaatctggatgtatatgtgcaggtc acagaggatatgatggcttagcttggactcagaggcctgacaggttgctgcagtgagccaagatcacactactgcactcc tgcctgggcaacagagccacaaaaaaaaaaaaaaagaaaagaaaagaaaaaaaaagaagaagaaaaaaaaattttttttc caccaagaatttagtaaaaaattatagggaaaagtgtcactaattcaagggaattgcactgaaaattattcattcattca acagatatttattgagaagcaagtatgctggtgctagggttacaacagcgcacaaattcttgtattcaaggaatgaggta agagtatgcagataggagccagagaggtcaagaggcaattgcaacatagagtgacacgtgctccagaacacataggaggg cttccaggccccatgctgggctatcagagctggcttcctgcaggtggtgtggctcagctaaaacctgagaaccaagaatg agccttctgatatctcagggttaaatcggcacaaatgaaaccattttataaccaaacaacattttccctcctgaactgca ctttttctagaacccatttaatccttcctaacatgttcaatccagccccgtgatttttcagtcaaatgcaagatgcgtag gattccttttctgttcagtgctccccagccaatctttttcccttctcccaccccacagttactaattccagcgtttcagt tctcagcagaggatgacagttccaccaggagacatcagtgttatctggagacattttagttgtcccagctgagggcacag tgctgctggcatctagtgggtgaaggtcaggaatgcacctcaacatcctggaacactcaggacaatccccagcaacaaaa acctacccatccagaacatcaacagggctgtggctgaggagccctgctctagtgcttcctccttactgtatcctcatcaa ggagggctctggggcatgtcaggggctgctacaggctcctggcagatttcggcgacttactccagacttgtggaacattc aggattcttagcatggccacaggagagtcaggctgtccacaagcactctctctttcttcacccactcattcctgtcactc taccatttccactgccttcccaaatgcccatcgtgagtcccaccaggggccagaacaccactctctcaagcctccccagt ggcgcgtgcacacctggagaacatgtctcacatcccccagccagcgagacgtcctgagattccagcacttctcagtgtct ttcccagcttgtttgtatctggaatggggtggggtctctcacacaggagaaattacaaggaaaagtgtacgtgacaggaa tggaggaatttctgtggaaacggtgtgtgagaaaatgtaggaagaaagaaacttcaggaaatggtaagtggcatcttgag agcagaaagtgagaagggagcagaaagaaatggggctggaacctgggaaggagaggacaggtggggatggccttgcacac cgtgggcactgaggagtgtgggcccatggcatgggtggagaggagtttcaagatagggagtagattcctattttgaactt cggattgcccctggcgatgtggagactgtattggaagaaggcaagaatggaggagagcccctaggtggaggtttggcaat gctctctccagaatatagcagaggcctcttccaaggtaggaaagccctgactggagagaagttaatggctctgagggctc aagggaggacttggattatcaggacttttagggaggcatatgatcaaggcttgggtcttggcccattgaaatggggagca ctggttttaggatgtgggtcaattagtttggttttcaggacaggctgagttggata cctgggggacctccaggtggcag tgtcaggggaagctggatgtgctgacactgaactcagcagagtgactgagtagagatcgacatctggggtcacaggcagt ggatgccgtaggggtggactcaatagctcaagcagaacccggaggaatgcaggcagcaaagggagccctaaagaacagtg aggagatgtgccaagaaagagccaaatccgggggattggctgtgggagagagggctgtgggagtaagaggaagtgtcagc aacgtcaaatgttgcagagacatagagtaaggtaagagtggaaaaaacatccatggaaccctgtgatgcaatcggaatgc agaaagactttgtaactcctgcctggtctcctcctctgcccactcatggcaaaggaatacaaagtaatgttccctccttc cgcctagaaaagcacaacttctgcccccaagccctgggctctcctgagaggacaggaccagcctctgaagttgaaggtcc tggttctgcccccaagccctgggctctcctgagaggacaggaccagcctctgaagttgaaggtcctggtttaccagatag ggaaggggccctttccaagaccctttccagaaggtgtggctgagatgggaaccgtggactctgtgcagatgtaggagctg gctccagtcaagtgctaggaggttgtgggtcctgggaaggaagaggctctggagcctctgtggagactctgggactgtcc ttgggggagacgtgagcaggaagaagcagggccttcacagtccccagcttaggggcctcaccacccagactgaagaccag gaccaaaccctttcctgcacagttacaatgtgtcatttaattttactaaagggaatattttttaaatgaggatgctactt tgtgtattaatttttacctctattca aaaagaaacgtttcttatctatttaagatgattcatatcagaccagtgtctgc ccaactcgactgaccctgtgaaaactgggcacttcacactccaatgatgatggatgagtccccagcagcatagtttaagg gagtgagtgggcagtgtggcctcctgtgcacgtgacttcctccttcagtgtgcccacatgtgggttccacggtcttgtga cattgtggctttagaaatttctgtttccattttctatcattcagagtaaatgaaatttgcaggaaattcagaaccttcca cctgtacagtggatactgtgagactctgcccagatgccctcttcaagccaatgcatctctccatgctcccactcccatag atgggaacagaggtgctggaactcagatctactcccctttctgggaactggagctgcctgcccaggcaatgcccccttcc cagggatggctgagccaatgactggctaatgttggattgcagaggcctagcgccctcccctcaattcctaattccttgta ggaataactgaggcctcctctgtgaccacgtgggcagcttctccctctgcctggtcctgtcttgttctctcctttccaat tgtgtctcctggaagccctccccacaagtctgctgcatacaactctccttctcagagagcctgagccctggattcccagg aatccagcctaaaatagtctggcatttggtttcaattttctctttcactaagactcagtcacaggtgctaataaataata aaatgtcaccaccttgaattctatcactctctcttttcttgccccatctctgacaagtaggtggtccctcaagaacctga aaagcagacattaggaggaaaggaggagtgggggcaagaggcccacacctcacctggccggctcccatccatgcgccctt gactgaggtaacacctaccctgggaatccttcccctgcctctcgtgagccaggccgggtgctcttgggacagctcccact gctcctgtgtgctcccccagcttggcacatgactccctgaattatagtcagttccgtacctgaatctccctctagaatgc cagtgccacgaggacagaggacggttccactttgttcactattttctccccagggtctggcaaagttcctgggacttggg agaggtgtccttcaggagcttggcagaagccaaacggcacacttaagtagggcaactgaggtgagtttaatgaaggattc tatacaaaaatttggacaaggtatagggaggccacaatacacagtgcagtgcctggtgccagtgagagcagggcactatt cccactgcaaggccagacagggcaaggggagggagctgcctgacaagagctgcccttacgtcaagggacacatcagccca ctagaccccatcaggagggagccagggcctgactcccctgaccttgctctccaatcttctgcctaaaattccccatcagc caaacacaactgaaaactgaaagacaggggagcctgctgttaataaggtgagcttcccccagaataaagctgggtagaga gtggagaatggatatggaagggcaaaaggaagatttataagacagtgggcactaaatatctatgagatgaataaaggaac cacattttacaacaaacggtcattgaaacgctactcaatggaaagagatcatttcggtcactgtctggtgcagacaaatc aaagcccacatgcatcaaaaaggccatgtccgtgtaactccgacacggggcagacagcaaggctgaagcctatggggtat gtggagccggaactgagagatcctgatgtaaatctagcacttgggaaaagggggactagaagaaattcacccacaggcag aggaaaacacaaacacttatctatttttgcctaggctttaagtggtatgggaaaaatctctgagactacaaatcctgtgc ttcatgcacaggtttataataccctcaaaatggaagaccccaaaaccaggcgcggaaaattcatatcaggccattgatgc cctcaatgttcccggctgaaacaaactcaaaactcctctggaaaggagtgctcccacttcaagccatgaaaagctactgc agagaaaataatccccagtcaagacacactcacattgaaactgcaaggcacacaaggaaatggatcaccttgagtgatag ctggcagagctaataaacctctgtatacctctaagaagctccacgcactagtataacccttaaagatttgatgaaatcat tactttattaaaattgtttttataaaaaatcaaaatccaaaaaaagcaacaaattttataccagagccaattcggtatat acaagggtgtcttactcttttggaatttgtcttattgtcctaactcagcacattgtcctggtctatgaaaagtcctagaa acccttctaccctctgtaatgtaggagctttaactcaatagggttttttaaattcttttttcttgtctttttttcttttt taattttttccattttttcaagtcaaactgaagaaatatttttcttttctttctaggaatgcatattcaccccccaaggc cacttgtctcctgattggagagtattagacaattctcaggatttctttattttccttctttattccataggattgggaaa cccagtaggattgggtttaggcatatctctaaagcaccatgtttcaacgttttgatgtaagattgtgccctatttcttgt tcagttgctgccagcagatgttatagttttaaaactagtttttggtcattgagatattagaggagggaagagtctgctat cctgctttactcatcttcatctacactacactgtcatcttcactgcaaagtcctgtattaatgtttttagattctataac attttaacaggtgtcaaaaaatcttaagcaccacttcagcttgggaatctctaaatgtaatggtgtttgtgggctggact gatgtctgcgtcttgttgttgttattgtctgtagtaatggagagccgggagatcctggacacttcctgttcatgggcact tgatgcattagctgccccagcagctgattacatttaaacaaggatgtgtgggtgaacccagggagaccaatctcagtgga atggtgggggcagaagccaggctgcagggtgtagagtagggaatgagcagtgatgaagtagaaacagagtttggacaact agtgaaactgcctggaagagggggagaagagacagtaaatggtctgaccaatgtttgaggtcaaagtgggtttgtaatct ttatttaagggacagatctgagcatttaaaaattctgaataatctaatagagaggaaaaagttgggactcaaagaaaatg tgggaaaaaatgatgaaggttaaacggaatgagatccagagtgcagggggagagattagcctttggtgttagaggagcaa ctctgtccatggagagaggaaaaatgtagacataccacagttgcatttgaagttggggcctgaggagttgaggagttctg agaaaagcagaagatgagatcatttcctgagagtaaatgggagtcattagaacgggggtgaagagactggaagctttagg tagcttgaaatagttgatggaaaaattggataaagtgacaatttgtcacactcagaacagctatcagggaatctagaaga atctctggaagctagttgaagatcttaaattaccaatgtatcttgtccacatagctaagcggttttacttatttttattt ttttgaaacagggtctcactctgtcacacaggctggagtgtagtagtagtagcacaatcacagctcaatgcaatctctgc ctcccgggctcaagcaatcctcccaccccagcctcccgggcctgggactacagacacacaccaccactcccagctatatt ttgtacatttgtagagacagggtctcgccatgttgcccaagctggtcttgaactcctgggctcaagtaatctgcccacct cggcctcccaaagtgctgggattacaagcttgagcccggctgctaagtggttttaaacagctgttctcggaaacacacac tcaaagaaaaaatgtagaggataatttatctaaggctggggcttcaagagaggtcagggtgttgacaagagaatgactaa gtggcagactactggatctcagctagataaagagggatgtgatcgtgggaggggctgatagtcagaggctggaaggcttg atgaacaacacatattacacaaagaataaatggagtgagagaaaccaaaggagtaaaagttgtcatcagaaaagtgagaa attttattgtgagaattcagtggtaaatcaatgttaacaaacctcagctgggcactagtggagtgaaaccgaaggccagg gagttgagttaatgagctgagacttgggcaccagatgggggtccacatggacaactaagccaccaggatgatgtgggaaa ctggggtgaatagaagccccttatccatgtgcacaagtcttgaataaaataggggcaaccaggcagtcagtggatgatag cagtgaggtggagcagagagcaatgtagttggagaagtggagcccacagcagtctcctttatatctagaagggaattaat agccaaaaaatggcaccgaggccaaggatgtcaccttctgactcccaaatctgagacagatgtgagagggaaggagtatc ctcaagggacaggagatggtgcgaatgtttttggcataaatcaaagatgtcagggaaattgtcagaattcaggttccaga gacacagaggaaaagcgtgggagaaagtggaatattgggaggtgagattagggcagaggaagcacaaatcaaagaacgag gaatagaaaaagtcatatgagctgaggagttggccaaacatgacagaatgggaatatgatggaattaagtggctttatgt gttccaaaaggattggtccacgcaggccacaggaaaatgggaggtaagaagaaagggatcgaaatgctgcaaagtgtatt acttcatggtaagcaaaggactcaagactctagaaaatgatgcccttccttccaagactatgttagtccaaatctttcaa gatacagaacccaaggtggggtctggcatacaagaagtataatagaggaaatgtctgtgacatttgcaggactgcaaagg gagccaggagaagctgggaaagccatgagatcacaagcaggtctgactccaagtgaaggagatggggaatgacgcaaggt ttggctgaagcatgtgccaaaggcacccatcagaggagtccctctccaagggatgggcctatcatagtgtccctaatagt gtcatggagtgggagcagcccacggagggcacagccttggcatgaacgcagacatgggtctcagagtgcagcagctgggc ccctcagtcaattaggctccctcagagctggggcaggaggtgcactagaccacacagtaatatttatttattattaattt aattaataatattaatttattaatttaattaataatatatttatttatttattattactagaccacacagtagtatttgt atgtctaaggaagcatttctcagaatatactcactgaacttttagcctataagtacctgtatgaaaattttaaaaggggt ttcatgatcaaaacattttgggaaacactccataccctttcttcctcatgaaggatcataatgcctattagtatatgaag ggctctgagaagtcctgtagtaaagaaacttgctttagttttttagtccagcaatttttcaaacttaaatgagcaatagc ctcccatccttttttttacactttttagcatactgcggaataaactcaacatgcattgagaaagactgctttagggaata gtcaacactatttcactcccagtaagtacatataaaatctgtatttccagggtggattatcaacacagctgtattttaga aatattatctgccctcccaggtatcacagctactaattattgggtactgaggtggaattttagggatcagccaattatgg gaaagaaaatctgggggcaggataagatggtctccgaagccttaaaattatatgccattatttacctctttgatctacta ctcaatatcaaacaactaattcagaagaaaattgattgttttctaaaagtagtttttctacatttcccattaagaagcag tggtatttaaaacttataatggctattatgtgagattatcactatcatagtttttctctatacaaattttctgtaacatt ttatttgctaataaaaattagatagatggattgactaattgataatctaagaaagattatatttgaagaagccatagtaa gggacagattaaattatcatcagtctaaacattctaatacctatttctctttttttgaaattttccaaatttgttattat gcatttaaacaataattttttgaacttttattttaggttctggggtacatgtgaaagcttgttacataggtaaccttttg tcatgagggtttgttgtacaaattatttcatcactcagctatcaagcccagtactcaataggtatcttttctgctcctct ccctcctcccaccctccagtctcaagtagacctcggtgtctgttgttcccttctttgagttcatgtgttctcatcattta gctcccacttataagtgagaatacaaggtatttggttttctgttcctgtgttagtttgctaagggtaatagcctccagct ccattcgtgtttccacaaaaaaacatgatctcgttcttttcatggctgcatagtattccatggtgtatatgtaccacact ttctttatctaatctgtcattgatgggcatttaggtttattccatgtctttgctactgtgaatagtgctgcaatgaacat tcacatgcgtgtgtcttcatggtagaatgatttatattcctctgggtgtatacccagtaatgggatttctgtttttagct ctttgatctaatacctatttctcaagatcaagttagatctctaaaaaaggcatcatcctagcatttccccatcccttccc tgaactaaatttaatgttgtgtgtatcaatcagcatacagtcaagacagaaaccacacatgaacattaaatataatgagt tattaacttataaaagggtatgaactactaaagggggtaaggagaatgctgaagaatgcaggaatggcagatgtagagag cagccataacctctaagctaaggcacagcagccaaggaaggggcgaactcaaaaaatgccctccctccccagctgatcca cccttgttggagggggtgtggctgcaacccaatggatgcccaagaagtttgcagagttgtggcaggttggggctgctgag caggaaactgcccgaaggggtaccagtgagattcccaagaatgtgggcatgcctctggcgaggaagacgctcttggagtg ccagcaaaatttactaggaagctacccagtagggtgccagcaaaagtcagcaggaagccactgtcgtggtgtcggcaaaa ttcactgaggagtgggcactgcagggtctccacccagcactggcaaatcagccaaaagaacaaaaacaaaataaaaacaa atcccagaaccagaaagaaaaaactctgcctcttactgcgaccctcttatgccttctacagcaactggcaaaggagaaat gtttatggggtccagctctagactcacaaagcagaacacagaagagtgaatgaagagctgaaaggcgataaatcagtaac tggagcctcacatcctttgccttttttattgagggtcaatatattaagaagaatatgtctgcgtcttcggtaaaattatt gctaaggttatcacccagtgtgtgttttcaacctccctgatataagaacttagtgacaagaaagaatgagacaatgatca tgaactattggacccaaccatttgtggctttagtgcccatcttctcagcaaggctttctctctctctctctctctctctc tctctctctcttttttttttttttttttttttttaagatggagtctcactctgtcacccaggccggagtgcagtggcaca atcttggctcacggcaacctccacctcctgggttcgagtgattctcctgcttcagcctcccgagtagctgggattacggg cacccatcgccacccctcctggctaatttttgtatttttagtagagatgaagttttgccatgtcggccaggctgttctca aactcctgacctcaagtgatccacccacctcagcctcccaaagtgctgggattacaggcatgagccaccacagccagctc tcagcaaggctttttctgactacactatttaaaatgtgatccctgagccaccttggcctctcttgctgtccttccctgct tcgccttctccatagcacttctctcctactaatctacaatttacttgagctctgtgaaggtcaggatttttgcctatttt gtccattggtgcatccccagcacctggaacagagctaggcacaggctaggcactctagaaatacttgctgaataattgaa ttaagtaaatgagtgatctacacgtagtggggaatgagagtatacagtgatagttccttcgactaaaactggggtcaaat tatagtgataaagaggaactcagaccttcagaggtaagctttgtggaccacttgccaaggctgcagaatgtgatgtcgtt tcacaaacaaggaggccctattatggcttcagatatgagaataataaagagaactttcctttcgcctcaactgcagcctt ctaaactcttccttccttcctatgtagaagtttcaaggacctcatggcctgagtgtggataggcagaatgctgggaatca ggcaaaaataaaataatactgaaagtgaaggtcatgctaatattagtaagccagggtgatcctgaatttacaaaacattt ttctttgggaaatttcacacctcacatgattctgtgtttttacttgggaaatttcacatctcacatgactctgtgacatg cggtacatgaggtgcctgactgctgtttttgtcctctactaatgaggaagagtgtgcgtactcccagcgttttgcaagtt tcaaagtctgacttgactttccttccttttcctggaactgatccatgagtatcgagagtaaagctgcccgcacctactca ttcaagatcctgagtgtcctgcccagctgcaggaggtggagagacccaggaggaggggccactgctgatcccaggctgta gggggtgggaagagtgtcccagggcaccatgacccccactcactcactcacaggagacccacacaagagaggagagggca cttacagcttaggttcccaccagcaccaactcctctgccatcaaacatcattgtgtttctctttctgccttgtctg cgg cacacgtggagttaaatttaatgctcaatcacatatttgtctgggctctttctgtgtttatttttctcttaatagttctc tctcctcccttcctctccccgcccctcctcctccttcttcttttttttttccagagacagtgtctcgctctgccacccag gccagagtgcagagtggcatgatcatggctcaccgcagcctccaactcctgggctcacgtgaacatcccaccttggcctc tggaatgtctgggattacaggcacttgccactgcatctggctaatttttatattgtttatagatccgggatctcactatg ttgcccaggctggcctcaaactcctgggctcaagcgaccctcccacctcatacttctgagtagctggggctgtaggaatg cgcctcagtgccaggctagtttcttaattttctatttctattttgacaggtacaaattttgtattcaatcctacctcaga cacatctttggtgggaaaaggatgtcatttaatcaatatataaattctaagcaaataggtctgatccccaaattaggtta gtcacagctgctgagtcgttgacccaagagaagctcatctagattttttcattattttcaagttcctcttctcggttcgt ccttcttccagaccatgccctccccgtcccactctcttcccacagcctcccctccccacagcctcctcccaccattccaa a ctgggctgttctctcaatttccttctctctggactcaaacctaccctagcccccagcctcagtttggggttaaacttg tcctcctcacattctctcccacccaacttgatgtcgcctctgtgtcatcaccacgggattttcctcctctgggttctcct tttccgagtggggtcagctcccccatgagtcacagcaccaatcacttctggctgcttgcaaacccctttgctttcctcag tgttgacacccagggcagccctatgctcactgccgctgagaccccacctctgcccctggccttttcccagctgacatcac cctgtggcttccattttcctaaaattctcttttgaggcctcagtcttaaccaaagcacacagtgcccctcaaaaatgaca ataaaaacccaaacacaccgtgactgtcatggcaggttcctggtccccgtattgaatcagcgggtgggtttctgcgaaca ctggtgagaggccgcattagagggtcaggaccctcaggtctggactcgtggtcaccacataccttcctccctgctgacag tagctggtacctgttacctactcagagtgtcacatgccacaagccagagcgtcttggcagttctcagcaccttgacatca cttccttgctaccactcagagcggcagtgacacagttcccttatctcagaaggccagaagacggctgtcaaaggtcacag ggaaatcaaaggcggggtacagggccagagggaggaggaaacaacttcccggttgctttcagacgcttcagagatcctct ggaggcctgggggagcttttgagtactttatttcagttggtccctgagctcggtgagtggggcgggtagagccaccaggg gaatcaacagtggtttctcgtgcccctcagggtcaggagcagtctgatcaaaaggagggcatccactgtccggggccatt cccacagctcccggatgctgggtctggaggctgcgcccttcccctgcaggagctcagcccagtggtaagtcatctgtgtg tcatctatgtatttaaccccttatggccatgttgatgctgagcatggtttcacttttgcaaacatttatttatacccttc gagagaaaaacgtctcagctgtcacaggaagctgcttcggggggtgagcaaactttttaaaatgcagaaattatgatcta cacccgtttcttaaaagtaagccatcgtacttggttctctttaattatatattttcttacatattgtgttcatgtaggca agtcctgtttctgctaaaagaaggtaagttctaccaaggcggtgtcatgccagctttatttcccgtggcacctggcacac tgctaagcacttacatgcttaacaactagattgggaatggtgctgctctggggaagtgggcacacgttaaagaaatgttt atttcagtcttctgaaatagggaattactctggctaaaatgtagctccagaaagggaaagtggggctgtatgaatccagg tccagtttgttgtttcctccaggataaggcagctgtcggaggggaaaatcatctcccatttctccacagggcagtctgaa gatggccaattacacgctggcaccagaggatgaatatgatgtcctcatagaaggtgaactggagagcgatgaggcagagc aatgtgacaagtatgacgcccaggcactctcagcccagctggtgccatcactctgctctgctgtgtttgtgatcggtgtc ctggacaatctcctggttgtgcttatcctggtaaaatataaaggactcaaacgcgtggaaaatatctatcttctaaactt ggcagtttctaacttgtgtttcttgcttaccctgcccttctgggctcatgctgggggcgatcccatgtgtaaaattctca ttggactgtacttcgtgggcctgtacagtgagacatttttcaattgccttctgactgtgcaaaggtacctagtgtttttg cacaagggcaactttttctcagccaggaggagggtgccctgtggcatcattacaagtgtcctggcatgggtaacagccat tctggccactttgcctgaatacgtggtttataaacctcagatggaagaccagaaatacaagtgtgcatttagcagaactc ccttcctgccagctgatgagacattctggaagcattttctgactttaaaaatgaacatttcggttcttgtcctcccccta tttatttttacatttctctatgtgcaaatgagaaaaacactaaggttcagggagcagaggtatagccttttcaagcttgt ttttgccataatggtagtcttccttctgatgtgggcgccctacaatattgcatttttcctgtccactttcaaagaacact tctccctgagtgactgcaagagcagctacaatctggacaaaagtgttcacatcactaaactcatcgccaccacccactgc tgcatcaaccctctcctgtatgcgtttcttgatgggacatttagcaaatacctctgccgctgtttccatctgcgtagtaa caccccacttcaacccagggggcagtctgcacaaggcacatcgagggaagaacctgaccattccaccgaagtgtaaacta gcatccaccaaatgcaagaagaataaacatggattttcatctttctgcattatttcatgtaaattttctacacatttgta tacaaaatcggatacaggaagaaaagggagaggtgagctaacatttgctaagcactgaatttgtctcaggcaccgtgcaa ggctctttacaaacgtgagctccttcgcctcctaccacttgtccatagtgtggataggactagtctcatttctctgagaa gaaaactaaggcgcggaaatttgtctaagatcacataactaggaagtggcagaactgattctccagccctggtagcattt gctcagagcctacgcttggtccagaacatcaaactccaaaccctggggacaaacgacatgaaataaatgtattttaaaac atctatttaatgtattttaaaataatttgtaagttgattttaaaaccaatttaactacattccaaattatagacagccca tttatatgggagtaacttttcaggctcattgcctcgccggtgatgagaagaactagctagctggaagctgtgggaaaaag aggtaaggtaacttgttctgtcgaagttctctaaattctcttgcttacttgccacacccctaggcccccagcttccccta acccaaggtttctggtattttctcgtactttatcaagactatggaatcttaggagacttaacaaaagcaaatgagaaatt atgtttagaaatgtctaacaaaatgaattctttgtccttttaagtataacacatacctcaggcctcaccagcacataact acaaaaggttgtcccacttcctttctgtggctgagttagtagaacacaggctcccacctgccacatcagcagaaggtcac ctcaacatgtgagctacctccccggagaccccccagatccgtaaggatgatgcatccttgatcctaaaaacattttcctg ttcctggtgttcagaattggactccacactcactggtctctttataatcttgcttctggccctttgaggcctcaaagcta ccagggccttgctgccaggggacaatcaccgctcccggctgagtcctgcagacatagggcctgggctggctgcctcctcc tgctggcccagcatcttgcttgcactaaagagagctggaggcttggcactgatgcttgctaaaaacctacccaggccgcc cactgctgccgcactgcagggcaccagcccacactcctcccctcctggcatcaggcacacgttcacggcactaaacctta caggaaagcagtggaaccctgtctttccttcacaggaggcactttccttcctaggcaaaaacgatgatacccatgggcac agcatctcacatagggacacatagagatgtctgactcattaaaacccaagtctctggccaattaaaaggggtccttaatg tcctactcaacagtggtggaaggaaatttgctctatattgatgaaatgaggtggagaaaatctgattttccaaacatgag aattctccatatgccaccccataaccaaagaccccttatttgtgttagatgaaacattcaaagagcctattaggatagcg gatgagacccccaagggacatgcttatacaacaataactggctccaaaccacactccatggcagtggctctcaaatgcca gctcacatcacaagccctgtgctaaaacacagagttctgggccccatcccggagtttgtggttcaggaggtctggagtgt gacctcagaatatgcatttctaacaaattccccaggggatgcagatactgctgacccaaggccctccttctgagaaccac tgttccagggagaagaaactcagctaagtaagggtttggctttgtgctgaagacaatgtggaatttagagttggggtgaa ttattcaggaaagtagagaggtttggagatgtgagggtgggaagcgcagtggagggaggcagagaggaaatatgaagcag cgtcagttggagagaaattaggaagaggaataaaatgatatatgccagggatttcagttttgctgagcccatgatgacag actcttctctggcaccttatgccactcattgagggcttgtagctggctctgctctttcagagtcataatagggctatggg tctgacctcaaggtgagctggaatgggcacaagtaatagataaaactgcaagaagtcactcaagggtccttcctagaaca aaggatccctacattccaaaggcgaatgccggtcactatcataaaagaaaagaaagaaagaaactgatggtgacatttta aatggcaatttttctagcttctaaaaggttgtggagcaactggaactttcataccctgctggtgggaatgtaaaatggta taatcactttggaaaaattggcagtgtcaccaaaagcaaagcctatacctactatccatttcactcctcagtatttaccc aagagaaatgagcatgtatgtccatacaaagatttggacccaaatgttcatgacagccttatttatatagcctcaaacta gaaaaagtctgtctatcaacaggtgaatggataaacaaatactggcctgtgtatctaatggaatactgctcatccacaaa aagaaacgagctattgatacacacaggagcatgcacgaaatctcaaaatgctgaatgaaggaggccagattttaatttta tttttaattatttatttatttatttatttttgagacagagtctcgctctgtcacccagcctggaatgcaatggtgtgatc ttggctgactgcaacctctgcctcctgagttcaagcaattctcatgcctcagcctcccaagtagctgtgactacagtcat gcacaagagcaactgactaatttttgtaattttagtagagacggggttttgccatgttggccagctgctctcacactcct gacctcaggtgatccacctgcctcggcctcctaaagtgctgggattacaggcatgagtcaccgtgcccagccggaagcca gatattttttaaaagtacttattttgtgattctatttatataaaattctagaaaatgcaaacaaatccatagcgacagca aatcagtggttgctggagatgttggaggggagaggagaggaatagattgcaaaggggaacaaggaaattcggggggacag tggatatgtctgctattttgactgtggtgatggtttcattggtatatacatatgtcaaaaacgtaacaagttgtatacgt gatttattatgtgttgactatacctcaaaaaggctattttttaaaatccccctcaggctccaggcactccattacgttgg tgtgact'tgtcttggaaatatactttgagcatttgccggaggagatccagtgcctgggcctctgtttcttctcccaagta gaattggcagctaaaacgggatgcccatgggcacaacttgtcacccccatcaccgaacagggagcagaaggaggctgctg ggggtgcccccacagggagcacagtctcatcgggaatgacctgccatggcaaataaaatcaccagggcaagtcaagggag agaccagggaagagagtgatccagtctatattaaaaaaggatgagaaaggttgaagaaaaagagaagaagggacagaaat tctcttcacacatttgcagaagtaggtccggactctccatccacttctcctcctccgataggtaggacaggaatctcaga ggaaatggcatcatcttcccatgtttacagacacagcaatgaactcaaagaacaatcttatcaggattttccaaatgaaa acatggagcatatagagaataaagatccataaactcgtatggtggctgagactgaaatggttaatgaaaagcaaaagtgt gtgctgaatgacaccagccacaatggcctgaacacttaagtagtgtaatatacttggaacattgacagctaacaaggtct tcctcccatgtcagaccaagaacacagtttcctaaagataaaaatagcacatgcttttccacttttccataagtgactgc attagaaaactaacaaaccatgaaaagcaaaatatggctagtctcttcaagaaaaactggtgtttctattttgtctgtaa attactttctaatacaaaaaacaattcctgttacattgaggtaattctaactagggacatatgagagagagattgaaatc tcatgagctgtctccttttcatctcaattctgtgtactcgtgggtacaaatggaactagtttttgtttgtttgtttgttt tttgagatggagtcttgcgctgttgcccaggctggagtgcaaaggtgtgatctcggctcactgcaacctctgcctcctgg gttcaagcaattctcctgcctcagcctcctgaatagctgagattacaggcgcctgccaccatgcctgactaatttttttt ttgtttgtattttttagtagagacagggtttcaccatgttggtcaggctggtctcaaactcctgacctcaggtgatccac ccacctcggcctcccaaagtgctgggattacaggcgtgagccactgcacctggcccggaactagttttaaaacaggaaac agttgatatactgaatggaaaaacaatacaatttgaagttgaaaaaacaaaataagatgcccagttaaatttaaatttca gttaagcagctaatagttatttagtataagtacaacccatatacgacaattgcagtatttgttatttatctgaaattcag acttacctgggcatcctagtatcctgttttttgttttgttttgtttttccctttgttttcttttttttccccgaaatctg accaccttaactttaaggtatttattcatttttaaaaactaaatatttttcggcagtcagaactagagcaaagataaatg atcccaggactctgtttagcaggcagtcaggaagtgtgacagtgtggtgggtggcagccccggccaggcctttcctcttc cctaaactgccacagcaggactgccacacttgggaatcccagtttccatctgagcagcccctccagagtttggaaggagt cagtgctttagcctgaggagccgtggatggctctaacactttgcttgtcggttgaataaaaatcaacccaaaggtggcct acactcattgaagtaggaatgccagaacttcagtggtgtcacatagaagaaaatatctaagtgcttagggagatggcagt gctagtggatctactggatcattaagactcactcacccacccagcgcaggtctagaggacacacccttgccacactggga agtgtaaatgagctccagcatctttatttttttttattttttatttgttttattatactttaagttttagggtacacgtg cacaaagtgcaggtttgttacatatgtatacatgtgccatgttggtgtgctgcacccattaactcgtcatttaacattag gtat tctcctaatgctatccctccccccgcccccggtgtgtgatgtcccccttcctgtgtccatgtgttcttattgttc aattcccacctatgagtgagaacatggggtgtttggttttttgtccttgtgatagtttgctgagaatgatggtttccagc ttcatccatgtcccgcatctttaaaaaaaaaaaaaaatctctaagtggtggctcttctctgtagatcaggagctgtagtg agcaatgctacaaaactggagtttctaaatacaggggggatggtgggattctgaggaaggacaggccacgtggtaacact tacaaaagaccaagtgggtgtggttgccactgtggacggtggagccaaagcagtcctcagaatagtctgacccccagagg tctttggcattggctggttgatcatggtgtccctggaattgaaatagaaggacggtctactaaatttttacctgatctgt a aagcagaagagttctatctctagtgaacagaagtctaactttagtcaccagaactgagagtcaattcaatcaattccc agatttgacatagtttatagacctagaaccccttgaatgaaaggtaagctggctccccttgaggaaggaccctgttacat ttccggcattttattctgataatcttttttcccagccttccccaaagcaacttagggccatttaccagggaaagccatgg aggaaaaggaaataattaggctatttggagattccaggacactggctctacgctgacaccagttctaagagacccaaaat atctttgtggtctaccagccaaagtagggcttcatagaggtcaggggtcactagagtttgagctcaggtctgtttcactg tgagtctagagggtccctgaacttatcctatagttattcccccagttccagaatgcagaattgagctgagagcagtggct catgcttgtagtcccaacactctgggaggcgaaggtgagaggatcacttgagccaagcggtttgagaccagcctgggaaa tatagtgagaccccatcttttaaaaagacaaagaaaaataaagaaaattgacatggaaaaataatataaaatgtgaataa tctcacatctactaaagaaattcaatctgtaattagaactcctcccacagagaactataagcccagtgcccccatcaact ggagaaacagaaagaaacaatcttcttaacagaaagcataattggaatagagatactctgcatcggggaagaatccccat attgattctctgatccatagagtgaaggccaagtggaagcctttggaactccctctacctgccaagatactaaacaaaac aacactgcacgtctggaggaattgtagcaagaacttgaaagatgaaggatgatgatgtccacctctctccattcagctca cctatctggtttgtgcagaagacaaataggtgttggaaaatgacagtggaccagtgtaaacttaatcaggcgggggctcc agctgcagctgcaggatcaggtgttgtttcatttctgcagctaatcaacccttctcctggcacctggtgtgcagatggca atttttcttttctattatctgttagtaaagactatcagaagctgtttattttcagttggcaaggtcagcaatacactcca agggaagagcagtctgtctcagatcttaccgatgcctggggatagggagggagtggccccctcaccgtctccaaggccta gtcctctgctcctgctactggcagcaaatccacgcaggtctgcaacaacctcaattcctgcctcctcagaagaaagaatt caattgagggacgtaagacagaaggagagactgaggcaagttttagcacaggagtaaaagtttatttaaaagctttagaa taggaacaaaaggaaggaaagtacacttggaagagggccaagtggacgacttaaaaagcaagtgcgtggtttgacctttt gacttggggttttatacgtcagcatgctttcggggtcttgcgttatttctcccctggttcttcccttggggtgggctgtc ccatgtgcctgcctgagcccactggctcaactcctgagatcttatagggaaactactgctcaccagtttcgagtgttttc tatctattaggagccggcttttccctgttgccgggtgtgaccaattattactttagaaagacagtcaacaaccgccagac catcacctgatggtcacctgacactcctggtgtgtggggtatggggagccctctcctgccctgctctttctgactagcta cccactataacactcccagagggacctgcacattttgtgctctttgcaagacagtgcctgcccagcacctgtaggcctgc tcaccccttcagggtcatgatttttgctttttaccgcaggtacccataagcaaaacatggcattgttcaccatgctttta cattattcacataattttaagttatttacacaacaatgtaaaaccatggtgaaccatgccacatgttgcttatgggtacc tgtggtaaaaatcctgctactagctcattttgcagtgtctataatgacaggtaatgctccattcactcctttatgacact tgcaaaaactgagaacataacgcctcccagttaagcaggcatctgggcaatgtgaggagaacagaaatagaccacgctgc atttatctctcttgatgacaggcattgagatttccactttttctggtttcttattatgtctctactgggcattcttacat acatcttgcacgccatggaaagtttctctagggcagtggttcacaaactttttggatacagaatacttttatgtgcttga aaactgaggaccccatacagctttagtttatgtgggtgtaaggttctagcccaaactgaagtccgaagggagttggtggg tgggtgaggggtagctgaaaaaacacccgaggaatcataggcagtttgaacatggccttatcctctctctgggcacgagc catatgtccagtgtcagcagggtaattataccttttacagacaatagaggctctgaagcaatcacgagctcacgtgagtg gtcacctaatgcacctcaagtggcatggttcataatgtgcggagtcgtgtgcctacgctccaaacccactgagtcatggt gcaccaaaaagtggcctcagcctgctcctgactaaagcgcagccatcttccttacactccacccctaggccaggggcatc ctccaggtagggacatgtgcccgtagggtggagccctgaatccataatccacagcaacaatacggagagcaacagctcat gactaggattccagctatgctacttatgactatcagggcccagcgtaggccagagcccagggatgtctaccatctctgca gggggtcatcagtaaggctcttgactaccttaatctcctgtgagaccccttgcagggctgctgttatgttctgccaattg tcagggataaaggtacaacattgtgttcctaaaagggcacaggtgcctccttaggcagcagttactatgtctaagaccat tcggtttcgcaacaccacctttctgatctgatcaacctcatccattaatgggaagagggccactcaggtgtaattcagag cctgagcagcatgctctgcaagagcagtaacttggcttctacagttgtgacacacactccagggctagtgcctgtcaagg ggtaaaaccaccagggtgctcattacacttgcaaaaaccgagagtgtagcacctcccagttatgcaggcatctgggcaat gtgagaacagtggcaggtacatgaggccaccctcaggtataatgtccagtccagtttgcttataggtaaggccaccctgt gtccccacagacccataaactcccagggggcacacagtccatcgaggccccttggtggggccgcgtcttccaccatacct ttggtgtggtgacatgtattatgcttacacacactgtgacgggtacccatcccacagtgctattaccccagtgttgctat atgcaccacagtgcctgggccaggggtactgcacgttacctcactagccagccccacccatcataaatgctatgggccag ccagggaatggctgtgctgtgggtcttgtggcatcctttgtccaaaacttgccacgttgcgttccaggcatcagccatgg gaccccaagtctccagccatgtctggttctctgcagatgctgaatgtatgtgctaaggcaagccatctgcagctgctaga agggcggtgcagatccaacagttggaaacattggtcacttcagtgtaggtgtgggcccagtccacaatgcagttggagca tgttaacctacagttggaatgacagagtaggcataggtactaacagaggaaaatcacatccctcaggtaaaatacaggct aacctttcatccctggataacaatgcagcccccaaggggttctgccctgggcaatagtaccacaccttttcagctcccca tggttcctttgggtcctgtattcatgcgaaagtcacaggggagcttgtagtaggccacacagacagtacatttgaaccct ggaggaaagtttcttccctggccgttttcctacaaacagttaacttcggggaccattcattgaacacccaaagagtgaca tacaagtcatactgtaggccctccccacagggagctacgatggacaaccaccagcagccgggggcttggaggggctatgg ccacagccaggttttctgttcccctgccttcagggacgttggggcaggcaacaacaggttactgttcatccccatacctg gtcagaggcggttacccttggtgtgtatctgcaactgaataggggtggtggcccatgtaacaaagcctccacctgggctg ggctgcttttccatggccattcattcaaggtttggagcatcaggtccagcctggaacttcagccctgcaaagacaggagt gtgacatgcaagtaaaacccattcttcaagagctcgctatatcactcaatcatacccacagcttgcaagttgtgcggtac atggaatccctactttatgtccattgttgtgcctgttgtccagtaaaatgtgtcccccatcactctcaatgaccaaaggg caaccatatagagcacataagtgttgcagggtctggatggtgtgctgttggttggccaccctgcaaggataggcaaacaa caggcctgtggctgtgtccacagctgttagcgcatgagtatacccttgtgacttcggcagcagcccaatgtagtctactt gccacctggtcaagggcacttgccctgttgtcacttgtgtagcactggacagctgcctccatttagggtatgcctgagca catgccgggcatttctgacaagcctcccaaatgtcttgcatgggcagagacagaccccaacatttattgacttgttgcat cagtttaccccctgcatgtcccagtttccggtgtagctacaaggccacatctcatgtagatgccaactctaaccatcgga ccttggccaaggcttctgcctcgtcattgctgggggtggccagaggcatatggcctgacaaatgataaatagttacatct ttgcaatgacccatttcccagaggtcttgctacatgggttggtggccccaaatgggttggtggccaactagccaattctg tattttccaagtagttaaacacaaagttaggcctccatagactgcccagctatcggtacggattaccataggtgtctccg ccttgttgatcaccatccatactgctttaaattcagcccattgactactttgtccacatctggtttcaaaccatatggtt ttggtactaagttggactgcaacactggtccaagcaggagtagcacctcgactagacccatctgtgtgccatgccccatc aggaatagagggatgcccttccttaaatggcagtggctcagggtcaaggggtgcctcaggccccatggccttctcttgca ttaggactgcaggtcccaagacctcttgcaactctgctgctaatgggcttgtgctcagcgtactctgttgctccaagtaa gtgcctcactttgccaaagtggatgtctgcaccatcccagtctggggggtcattacacatgaatgcacccatcccgctgt caggtaagtcatccacactgtgactgtagcccatcctatcacttctcacaagcctgaagggcagcatatacagctgctag ctatttctctatcaaggaataccagagctcagctcctttccatagttgggaccaaaagcctcctggcattctcaggcact ctgtgtgctgccacaggcccaaactaaaaccatctgtggtcacatgcatatccagttcaaatgggcaccccttgtcaaat acccacagggctcgtgcctgctgaatagcccacttggctgccaggaagccagtctcagccacatcagcccaatcccagat tgctcccttctttgttaactgatacaatggttttatcatttgagctaaatgaggcaggaatgtccaccaatatcccagga ggctcacaaaagtttgcagctgcctcaccgtggtgggccagggatatgcctaaattttgtcaatgatagcctcttgtatg gccttcatcttacccgaccagataactcccaagaatttagcaggtaatccaggccctcggaccttggatttgttgatggc ccaactgcatgctgccaaatgttgccacaagaggggtgccactgcttctaaatctgcaagagaatcagaggttaacataa tatcatcaacgtaatggaacaagtggactccctttggacattttcaggctgttaaatccatggcaacaagaccatgacat atggtggagctatgcacatagccctgcagcaacactgtgaaagtccattgtcatcaaggcaaactgttcctggctc cta gagcaaggtcaactgagaagaatgcattggccaagtccaccacatagtggtactgtcctaattccattgtcgagtggttc atcaaatccatgatagatggcacagcttccaagccatgtaaaatatccacctccagaatgtattcaggtatgggagagac atacacagtgtataagcaaggagccaagtggccaatgccaaggtacagagatacaggtttcactttcactgactggcctc cgtaacctttaatatatgcagatttgcccaaaaacttaactgggttcccataaacaaggctacaatctatgccagtatct accagcaccagcacccactgtacattggtgggggaccagtggattgccaattccacatgtggcctctggtcatctggtgt ccccccaagccagacacctttggccagttccctagttgaacagaaaaggctctacatttccacctggctgcagcaagtag tctctgagctgggtaggaccaggtcacacagcaatgcctttctcccctttgggcattttccggaattgctgccctgcata caactgtctccgcaaagttaggagtatttcattgggctgcttatcaattttctctcagtcaaccccagccaaaatcaaat ctatccacatctgtgagcgtgtcactcgttggggccccctttttttatgggggagccccctgtgggtggggtaacttccc cttctttatggtgtggaccctccaatccccctgaaggccttctgcttccctgagagccgccatggcagtggttacttcat gtatgcggtgccctacgtatggggtgaggacagcagctagggagccaaaggggctcaggagcatcaaacccaacatgaga tccctcatgtgggaggtgaaacatttatcatctggccctcaggtattcaggacaaacatagcctgccgcatacccatctc ccgaatgacttacaccaaattggcatatgactgccatttactcacagttttgggcatttcaccagcattattccacacag ttcatatggctgcctgtagccactcagtcagggtgtggtctccttgcgctgccactaaccacctgctcacttgcagccgc tgacagagagaggggtgagtcatggtggaggccagcttgtccatctcagaggtggaatgggagataccatctgctccctt gttccacagacgaagcatccaggcaggcaggggttcccctggacactggcaacactgcttgcctaattcctgcaactcag ttggggtacaggcaatatacgaaatgtgttgcattatggtggggagtccctgagtccacccttggagccccagtggctgt tcatgatctaccttctgtcagaccaccgggtgagcccgcaacaggggttcttcctccttggtatgaaactgagtggggat ctccagacaagatgatggacccaggcctgcattcatggtagcctctaattccttttccaagctctgaagccacacctcca ggcatcctgcctgcacctggaggtccccattcatggcagcctctaattattttccagatcggtgtagccagacctccagt ctgcatccctcagggactgggtgtgtacttttcttagcacagttaaaaatgcccatccaactctgccagcaaaggctctc tccttcttggtgctctgcacttccagctgcttcagcgccttctccatgctcatgggggacccatctactgccacccaggt ttccactcaagcccaccctcacagcacggctaccaccgggtaccacaacccatgttgtggtcacatggccaacctggaat cagcagggaccgaaggctcacttaccttaggatcctgttcgtgatgccaattgtcaggttctagcccaaactaaagtcca aggggagttggtgggtgggtggcaggtaactggaaaaacactcgagtaggcggtttcgacatggctttattctctctctg ggtgcaagccatatgtagtgtcagcagggtaattttaccttttacagacaatagtggctttgagccaagcacgtgctcat atgagtggtcacctaatgcacctcacatggcatggttacataatgtgtggagttgtgtgcctgcctccaaacccactgag tcatgctgcaccagaaggctgcctcggcctactcctgactaaagcacaaccatctcccttagagtgggctaaatctactg ctatttatactattagaaattttaacacagaagttttaaatatttacattgttaattgattttgaaataataagcccatt acaggttaacataattaacatacttttattaaaaatatctgtattttttaaaagaaaaaaaattagcaacaacagtgatc cttggaatcgtcccacctcagcctcccaagtagctgagaccacaggcgcacatcaccatgcgagctaatttctatatttt ttggtagagatgggatcttgccatgctggccagggtggtctcgagctcctaagctcaagtgatcctcctgcctcggtctc ccaaagtgctgagattacaggtgtgagccaccacttctggccagaagctggattctctgtcttgttctccatccaatctg ttagactgtcaaatgccaaataacctttggaaaattctactcgtaaaataaggagagagataaataacttctgagtatca tcattaaaatagtttgacctcatggacccactgggtcccatgtggagaatagctctaagctaaagagtagaatggctggg aggggacataaacattcagcccatagctgctgaccacaataacacattttaagtctcttcctctcctgctccttgtgatt gcagacagactcaatctgtaggagagctgtagagagaacaagctcaagcccctgattttgcctacaaagaaagctgagcc cagcaaagttaagggacttacccaaggtcacacagccacacagcagagctggggctgagctccaggtgtcctgctacaga ggccacttctttctcccactagggactggcctgtgattacttcagaaaacaatggtcagctaactgattctgaacgccct ttgctggtaaaagctaatctcctgaggaaaaatgtatgcattggctgggcgcagtggctcaagcctataattccagcatt ttgggaggtggagacaggtggatcacttgaggtcaggagtttaagaccagcctggcagtcatggtgaaaccccgtctcta ctaaaactacaaatattaagctcggcatggtggcaggcacctgtaatcccagctactggagagactgaggcaggagaatc gcttgaacccaggaggcggaggttgcagtgagccgaggtcgcaccactgcattccatcctgggcaacagagtgagattct gtctcaaaaaataataatagtaaaataaaaataaataaacaaataagtatgcatcacctcaggtggtcagtcagctttcc caagaccccaaagcacacaatgttctttctggtatgagtgacatggggttcacagcaccacaaagtccatgacttttccc tcagaagtgaatgcatggctaattattttgtattttttgtagacatggagttttgccatgttgcccacgctgctctcaaa ttcctggactcaagtaatccacccacctcagcttcccaaggtgctgggattacaggcatgagacaccgcatggcctgcac ctatagtcccagctatcaggaggctgaggtgggaggatcacctgaaccggggaagttgaacctgcagtgaactgtgatcg ctccggtgcactccatcctgggcaacagagtgagatcctgcctcaaaaaaaaaaaaaaagtgaacacacatgctggggaa gaggcctgcaggcacccctgccagttctgcaccagagcacactgtagcagccctgctgtgatgcaggaagcagctccagg tcctgcagtctgaagcatggagcctgaagcctggagccccccatccaatgctgcgccatgctcaccagtatcccccagca tcagcaccgaggcaccagctgcagataaatttctcacctaaaatgttgagagatgttgctaaactgtccttctaagggta tgtataataatacggtcctgccgatactgaataagactatctgtttcattacatcctcacaatactgaatatcattagca acttgaattttaaattgtgctaatcaatgaaaatgattgcctaattactagtgagttgaggttatttaacattaatactc cttctgatgaaatattttgcatttatcacattttacataaattctctctatataattagcactagaatgtccgacttggt tttcattgttcctcacctgtttggaaacacattaagaatgagggagagaatggatggggactcacctagggatgcatgga gctggtcggcagccactctgaggccctcttaacacttccccaccacacacttaatttcccctggtttgtccatagataca tccaacaatttttatgtaaataagaaagactcagctttcaatggaaaatggtaggttggattttatgactgaagtggcaa aaagaaataagggattttattatgggggaggtccaaaccctggtgaaaaacgaaattcattgaaattgtttgaaaattca aggattaaatcagattattttggattcagtaggaattagattactttaaagccccaggatactttattctgtagaatgca tggaaagtatagaaaagagaaacaaagagggaaagtcatggctaataacctggaaggggtaaatagggagccaaaggcct gtgggacgtaaccaactcagcattccactggaggctttatgatcaaatagcaagctatttatcatgaatgcaggatgtgg gcaaactcacgactgctcccactgccagaaggtttgctgagggcaatcacttcctggcaccgagctccttgaggttatct actgggacatctggagaatgcagtcttgcaagcctactctggacccagcagctgaccccttcttccatgcccctcttcct gctatctcttttgcctaataaatatggagggctgtgtaaagctcagggcccttgtccactagaggcaaactgcccgctga ccccttcttccaaatatgctcttttgtctcatgtcttttattcccgctttcaccccactttgttcagtccccctagggcc gtgtgggttacatagtggcgccctgaacagcgacagaatcaggtgctctacaagtggcgtccgaacacagggactatgag gatgtgaatgaagaagatctgctggagcagaggaattgaaattgacaaggtgaatggggatcccgggacaagtctgccgg cagcagatataaggtcagtgccctaaagaggtactgggagcagtgccttaaagtagtactgggaatgggaagttttctga atcagggtaacatggggcagaattggtctgttgaagaaaaacattatgtgcagttgcttaaagttttgttgaaacaaact ggtgctcaggttagttctcacattaactacgatgctacaggaagtcattatgcataacccatggtttccacaggcaggga ctcttgatgtagaaaattgggatagagcagaaggattaaaacaggctcatcaaaaaggttttcaagttgattcttcagtt ttctccacttggagtttagttcgtactgtacttctgccattatctccttgttattctgcgggacagcaggctgaatgtaa aaatctgaaagaatctgttgtcccacccacagctccagttgaaaataagtaataggagagggaggataaaaattggccta taccgccccctccagttgcagaaacatctgtaccgcctccttcggtggcagaaacagagaccccaatacaaagaatttta cgctctgccgccacggctggagagcccttaggaccttgcacttttcctatttccgtaagtcctgatccaaataatccaca gcagcttaatcatgaacacattccactagagtttaagttgttaaaggaattaaaagtgagtgtggtaaataatggcatac agagcccattcactttaggattgctagaatctatgtttggtgctatgtgtcttttaccctttgatgtgaaacacttggca tgaacttgcttgtctgctagcgcatatctgacatggaatttaaactggcaagaacagggtgcagaccaggctagacagaa ccatgctgctggaaatggagacattacagaggataggctattgggtaatggcccttattctgacctggtacatcaactag cactcacaaatgctgcttatcagcagtgcacacaggctgctaaatgtgcctgggccataattcctgaagagggagtccca gtactatcatttttacatatcatgcaagggtcacaggaaccctacgcacaatttcttgcaagattacaagaggcagtgag gcatcagattcctcataccttggctgcagaaatgctaacctttactctagcttttgagaatgcaaatgcagattgtaaat gtgcactggcaccggttaggtgtacaaaaacttgggaaattttctcagagcttgttaagatgtagcaactgagctttatc gatctgcaatgttagctgaagcaatggctaatttagctgttgacaaatctaaaaagagccaagggtcaaaccctaaaatg ggaaaatgttataattgtggaaaaactggacattttaaaaaggaacgccaccagatctcaggacagaaaggatcttacaa tgcttttccccccggcccccagcggaaagaacacctggactttgtcctcgctatgacaaaggaaataactcggctaatca gtgctgctcaaaatttcatcagaatggcacccccctgttgggaaatgagatgggggcctgtacccgggcctcacaaacaa tgagggcattcccaattcagacctcaaccctgtttcaggcatgggttcccagaggcatattgagtccctcacccgaggaa ctccaggaagtgcaggattagatctcccagccagagaaagggttacataaggtggggaagacaaacccaccaagattctc actggcatttggggacctttaccagcaggatatatgggactaattttaggcaaaagccaccttaacttgcaaaggcatta ctgtagtcccagaagttgttgactctgattatgaaggagaaattcaagtagttttattgtcacgagatcttcgggttttt gaaccgagagaatacataatgcaattattacttattccctgcaaattacacccttctccatgaaaggagaaacaaggaaa taaagggtttgggagcacagctacacgggaaatctatctatcccgacccatagcctctaatagacccacctgtgtagtac aaattaaaggaaagaaattttatgggtttatggataccggagctgatgtgtcagtgttaccagcaggtctttgttcttag agctcccaagatggcggcaagccttttgttctctgacctggagttcttggcctcacagattccaaggaatggatccttgg gccatgcagtgagtgtcatagctctattagaagctcttccaaaagtcgtgctgctatctatggactaaaacatactcaaa caataatgacctctggcgtttaggctcaatgctcagagctaattgcagtcattcaggttttacagctcacagcttcagat cctgtcaacattgtctgtgttcagtttatgtcgtaaatgtagccggtcacatagaaactgctacaattaaaagtacgcta aacccagaactgctaatttatttttaagacttcaacaagttatttgttctagtgcagctccttttcatatttctcatatt ccttctcacacacaacttcctgggccgctatctctaagtaatgagaaaacagacaaactgattgcctctgtgtttcagca agctcaaccatctcatgtgcttctgcaccaaaatacttccgcccttactcacatgttcctacaggtttgtattatattat gcagtatatccctcgagccacacctatagaaggatgtaatccacgaggtttggctccaaatgaaatctggcaaatggatg ttacacacacagcaacctttgataagctgagctatgttcatgtgactatagacactitattctcatatgctgcctgctaca tgccaaacaggtgagacagctggtcatgtacagcgacactgtctgtcatcatttgctcatatggggatatctaaacaatt aaaaactgacaatggacccgcttatactagtcatgcttttaaaaatttcttgcagctttgggctataacccataaaacag gaattccttataatcctagaggacaaggcattatagagcaggcacatcaaacattacaatgcatgttgaaaagacaaaaa gcgggtataggaggccaactaccacctcaataaaaactacatttagccttatttactttaaattttttgactcctggtat ggatggtaagactccagcagaaagacattggcaagtgttagaagaaaagaggaaaatttatccaaaagtgttatggaaat ccctggaagaaggaaaatggaaaggtctggtggatttactgacgtggggaagagagtatgcttgtgtttttacaggagat ggacaagccgtgtgggtgccctcaaggtgtgtgcaaccatggaacgggagactagaggaacccagggtggccaaccatgg acagggtccccccggtacgagccatgagccagctgagcctgagtgcaaagacggagagaaggccaactggagtcacaaca cagttctaatgttatatttgtaaagaatatcactactcaacttacagtttgtgtttatagatatagatatagatatagat atagatatggatatagatatagatatagttatagatatagatagatatacactttaagttctagggtacatgtgcacaac ttgcaggtttgttacataggtatacatgtgccatgttggtttgctgcacccatcaactcatcatttacattaggtatttc tcctaatgctctccctcccccagcaccgcctcccaacaggccctggtatgtgatgttccctgccctgtgtccaagtgttc tcattgttcaatttccacctatgaatgagaacatgcagtgttttattttctgttcctgtattagtttgctgagaatgatg gtttccagcttcatccatgtccctgcaaaggacatgaactcatccttttttatggctgcatagtattccatggtgtatcc ttatgtctttttgacagctaagaaggaccagctccaggtaaacaatacccaattgacctgtaaatcttaccaattatatc actgcattaatcatagcacattgcaaacacataatatctctactttgatgattttaggccacatccctgggctatgtatt cctgttaatctgtccgaggcttgggctgccacacctgctttgcattttgtgaaacttcttctaactgagcttactcatca tgtctgtagagccttagacataataattttagctattgtttccttggtcgcactaataacttctgttgtgatgtcctctg tagctttgcataattctattcaaacagctcagtacatggagaactggacacacacagccgaccaagcatggctacttcag aataaaattaacactgagttacaaactgaagtggtgttatgggaagtcagggaccccaaagagagggaccagctggagcc acagcagaggaacgtaaattgtgaagatttcatcttaatacggatatttatcagttctcaaataatacttttacaatttc ttatgcctgtctttaatctcttaatcctgttaccttcgtaagctgaggatgtgcatcacctcaggaccactgttataatt gtgttaactgtacaaattgattgtaaaacgtgtgtttgaacaatatgaaatcagtgcaccttgaaaaagaacagaataac ggtgatttttatggaacaagggaagacaaccataaggtctgactgcctgcagggtcgggcaaaaagagccatatttttct ttttgcagagagcctataaatgaatgtgcaagtaggaaacatatcgctaaattcttttcctagcaaggaatattaatatt aataccctcggaaaagaatgcattcctgaggggaggtctataaatggccgctctgggaatgtctgtcttgtgcagttgag ataaggactgagatacgccctggtctcctgcagaaccctcaggcttactagagtggggaaaaactctgctgtagtaaatt tttggtcagaccagttttctgctctcaaaccctgttttctgttaagatgtttatcaagacaatacgtgcaccactgaaca tagacccttatcaggagtttatgatttttctcctgtcctgtttcctcaggagcatgtgatctttgttctcctttttgccc tttgaagcatgtgatctttgtgacctactccctgttcttacaccccctccccttttgaaatccttaataaaaacctgctg gttttgcggctcaggtgggcatcacggtcctaccaatatgtgatgtcacccctggaggcccagctgtaaaattcttctct ttgtactctttctctttatttctcagccagccgacacttatggaaaatagaacgaacctacgtgaaatattgggggtggg ttcccccgatatgtgatgtcacccctggtggcccagctgtaaaattcctctctttgtactgtctctctttatttctcagc tggccaacacttatggaaaatagaaggaacctatgttgaaatactgagggtgggttctcccaataaagtggtaatgttga aatccacagttctatggttaggggaaaagcacaaagcttgcaattgcagcagcaattgcattgtcattttaatcacactc atatttgtgtaaccaacttagaatataaccaaagtgagtatctgtgggacgttgtgaaagcccatttgcagggagctttc acatctaacatcacctttgatattggtgaattacaaaacaaaattcttgatttacataggcaaattcaagagtttctgcc ttctttagaagactggaccaaattccagcaaggcctggagagcctcaatccttggacttatctaaggcactacattaaca tcttacatgtagttcttggaataatattgttttgtctctgtcttctgttcatagcctgtaaaattggatggaccaccaat cggaaaatgagagctgcccaccctggccttacattctttcaattaattcataaacagaaagggggatatttagggagcct aaggctcgtgggactgaccaactcatcattccactggaggctatatgataaaacagcaaactgtttatcatgaatgcagg atgtgggcaaactcacgactgctcccactgccagaaggtttgctgagggcaatcacttcctggcaccaggctccttgagg ttatctactgggacatctggagaatgcagtcttgcaagcctactgtggactgagcagctgatcccttcttccacgccccc cttctcact tctcttttgtctaatcactacggagggttgtgtaaagctcagggcccttgtccactagaggcaaagtgcc ccctgaccgcttcttccaaatatactcttttgtctcttgtcttttattcccacgtttgccccctttgttcagtttcccta ggtccatgtgggttacatagtggcaacctgaacaatgacagaatcaggtgctctacagaaataactttttaaggaaagat ttgggacttagagaccccaggagacatacacaaaaatgataagaggatgtgcccaaaccagtcttaaagttgtggcacag ggtgaggaagatgaagctgttactgaacctcagagagtgactggtgttacagcaaaagttagcaatggcctgaagggagg gtttctgaaatcaaatatgaatgattccccctcagggaacccaaccttgggaactactgcatggttctctgtatgggaaa atatcattaatgcaggataaattgtgaaatatcacaggaagcatcctgcatctagtcaatcttctgtttctggggtggcc tgtgcagctgtgcaggcagaggcccaaccatcctggtgagtggcacacagggactgagatccagccacacctaccaggcc atgctctgggaagggggtgggacctgggcaaaggacacctctctaggactgcacagaagcctttgtgggtgggtgggaca ttcctgtgatggccttctggctgggcactatgaaatgctctgaagatttttccttgcactgttgcactaaccccagtcct ctatcactgccccttcctcctgggcgacttcactgatgttgtggccatgtgaattctctggccaatgaaatgataaagat gatatggcctctgccaagcagacactgtaagtattattgtatgatgcttttgtctctttttttaaagttaaagcagttta ttaagaaaataaaggaataaaagaatagcactccataggcagagcagctgcctctgtctcttatattttcccctctgcct caagcccaacatgcccaaaattggggctgctggttcagcctgggtctcagaataaagacatgagccacagatccattgct gacccatgatggagatggacacaagagagaaacacatttttgtcatgttagccactaagattttgatttggaggccattt gctacagcaatataacctagcgtgaacagagagacacagcgatgttccatttcttttcaacctggaacaggagaatttca taggtgggcctcaatttcactttagtatcttatttagacaagaaagttcatactgttcaaatgtcatgtttaagagtgct ggcattatcactgctgtggctaccccatcagatgttgctcactgactaatcttctcatgttagtgaggatggacaacata tcaggccataattcaaagtagcaaataggaaaagagcttcatcctagcattatgggaccttaattaatgtcctttcctga caggtttcagaggcttttgcaggcagcagcagagctattcatctcactgacagtggggaacatggccaaatggttgcccc cacaatggaggcagagtttcaggacacttgtctgatctctgcccttgaaggaacagtctcaccctgattgacacttttgc ctgttatgtccaaagaaccaatggaaaagcaggaaaattattccttcttcatttctctcttcattatttaaaattattct gtcttcacttctctctccttttctctgcttcctacttagctctttagaaatgcaattataatcttttatctccccttcac cagacactcccaacagggcaagttcatctaactatgtgctcttagttagacgctacagagcagaactctctσccaccaag agactaccttgagacataacagtcaattcacaagccaaaatatgcccgctatgaaactctcccatctggaaattttttgg ctgcttttacaacctagttttgcccacaaaggcaccagcagtaaccaactcaactgcctggtagacaaggcaccaaagcc agtacccagaccctctacctgctcacttcctgccttgcatgccacgccccccatttaaaagcctctgctttctgctccaa aggtgaagcagttacccttaaggaaagaagcctgtacttcttcccctaaggtagctttggaataaaagtcactttatacc aaacctagctcttgttaattagactctgcaagtgatgagcaactgaacctacatttcagttataattcctatgcttgttc ttcctgccctgccttggggacacgcacacactcccaggcacatacatgcacgtgcactgagacagctatgtgaataacca acaagatccccttaggaaaaccggtgcttggcctggccttaaattccagacccttgggcatcatacccaagactgcaaga aagaggaggggctggacctgaaaaacttggaagggaaggtccaactgtacaggtattttgtcaggcatgtgatttcagta taaaattctagaaaagatgagtgacactttataaggagagaatatcaacaaaatttctcattttacttcttgctaagacg acagcagggaattgtaagcagatggatgggcaatccccaccttcagcaggggaggccaaggccccaacacacctggggag aagagctgggggcagtgaatggctgaggctttcttggggagctgggccatcttcttcggttttacttcctgaggaattca caggcttccaggagggctgtgggacacaacagagcaagagattcagaaactgatttcttccattaaaccagttatttaat ccaataaatcaaagagaatactaagagttttctctgcccttctcccatcactgagtcagtgcttgccacactcatattcc cactcccctactcctagcgactacggtgttcaagggagccagagtctagccctcaccagccagggtgtttccctgctctg gcctgagagacacaaccaccctgcacttgtctctgattgaatcgactgtcacattctcaagttcacaagacattggtggt cctctagcttctcccggaatgtgaacctgtttgcaatcatgttcacctgcagattcactcattcattcacagatccttac tgagcacctgctttgtgtgagttgctgtgctaagtgctggggacacagcatggatagactggcctgccctcaagaagcat gtggtctatgcagtcctgagctggctgctcacaagaagagccctgtagccatatttctcagagggtggtcctgacctgca tcacagtgacctgagttgtttgtcaatacagaaaagggtttctcaaccttggcactattgacatttggggcctgataata accctttattgcagggggctggctgtgctttgtttagtagcatccctggcctctacctatttgttaccagcagcaccctc tatgttgtaagaatcaaaaaaatgcttctcacattgtcaaatatcccctcaggggaaaaattgtctctcattgaaaacta ccgataaagacatttctggccctgcccccatccttggaccaacagcatccctaatgcccccaactctgggtgagggacca ggaataggaatctgaatgattgcagtgcacagggagctgtgcacactgaaatcccacagttatcaccgggagccttacaa tactctgtgatgtcttctaaatatttttaagggattaaattaatatcaacatatttccctggttaagatgtgttttccta cacttgaatttttttgagattttgttttctctatagttggcatctatggtaactgtctagaatcagattttttttttttt ttttttgaggaagggtctttcggtgtcacctaggctgtagtgcagtggtacaatcatagctcactgcagcttcaaccttc tgggatcaagcaatcctcctatttcagcctctcaagtagctgggactagaggtgcttgacaccacaccaggctaattttt aaaattatttttgtagaacaaggtctctctgtgttggccacattggtctcaaactcccgggctcaagccatcctcccacc tctgcttcccaaggtggtgggatgacaggtgtgagccatcacacctggctggttttgtcatttctcaatgcatatgtata tatgcacctttcattttactgaataaaatggattatcagtttccaaagatttcatgacagtgccgtcactatccgtacta taaaatttataaaaatttattacatactgctctattttattctctaattattttatcaatgagattataatttcctgaac tgtaaagagatattatctttccttaacatttttacacctgtgttcgttcctagaatgctgtttggccctcaaaccttgac cttcacccatggtggtttctcggggatgctagctagggtctacttacgggaggttgagcactttttcagattagtaatgc ctgcgacatactgtggtcccaaatatttttcatatgttgttttgccatggagtctggccagacactcagtgttgtcattg aacagaaggtttttggtttcagactggaataagcaaaacttgtccgggcagtcagatccatttctcccaaatttagcctg cgacaaaagggcagacagtgagtagctaaggaaaagaggaatttgtgggttaaaggaggcaaaggggtatttcttccacc caagaacagccctgagaaaaccatggggcagaaggagctgagttctggagtcattccacctccttagtggagtcccccac cccacactcctggtggcaggcccgccttgggcagcatccaggcctcacaccacttctggtcctacctcctaccatctgcc atctttccttccttcttaacctgtgaccttttcccatacaacttcttatgggtgacaaggcaacaatggaggggttttga gatctgccctcacaagtcaattgctcaggacattctaatatgcagctcttctagagaggcaggctgctaggaaaacccag gctcagccactaaccagctcagtgtgcaggtcggtcaccctgcctccctcacacagttcctgctctgtcccaggctccca tgtggggagactgagacccaaacccctcagtcacggcagctctctcaccagcaccactgtgtgtgcacattaagagctcc ataaaggccagttatggtggccagtcttgttattcctgagttgttttcttcaaaagcacacagagacatgatgttatatg ataaaaatagaagttctaataaaatcccagattttaagaaaattttgggatttcgttcaaatcacatttagagagcccta aatctatagggcaccttctgagtttgctgttttagaggcctggtctagagcactgttcactcggcccaggttcaggaaat gtcacctgagtaaaaagcacta actaatgcatgtgggaggaaggctcagtggcttcctcatttgccagaagaacagcag gagggaaaaagacagcctctgagccaggcagtgatggcaacaaggccagggcacagagtctcagcagaaatggagtgagt cccagaaagcccagagtcaaaagcctctgttgttcttgttgacactctgggcaacgccacagcatgaagccaatactctc accatgagcttcaagtagaggactagagaggatcgagtgggctggtgcacctagctctgtgatctcctcacctaacatga gcccacacagctaagaaagcactagaagccctgtggtccatacctgttggtggagcaacacctgtttcaggcgttccacc ttatccatccgagacaccacggcatgattcggggccatggcaagatggcagcttctagcctcagtcacaggcttccgttt gccatcgaggcacagcagcgcaaagtctgccagcttcaaatccttagcccatgcgtcattgttatttcctggggagaaaa agaaggtggcatcatccacgcctcccctgcttagccaagaagtctcttctgggtgggtgtggccattccactgacctccc aaatgcacacactggggttgtggtgatgtgaggaacagagaaggagcttcatcctacacaagctgtacaaacttcaaata taccaaatattagtgctgtgtccatgcaatggaatgttattcagcaataaaagggagtgaagttctggtacatcctgcaa tatgcatgaacctcgaaaacgatgctaagtgaaagaagccagtcacaaaagaccacacaataggctgggcacggtggctc atgcctgtaatcccagccctttggaggccaaggtgggagaatcacttgaagctaggagttcatgaccagcttgggcaaca tagcaagacctcatctcaaaaaaaaaaacccaccacatattatatgactccatttatatgaaatgtccagaataggccag cctatggagacagaaagtggattgatggttgccaatgctgaagaaggatagggcaatgactgataataggtgcaagggtt tctttatgggaggatacaagcgttctagagttggattgtgttgatggctgcacaactctgtgaatgtgctggagatcact gaattgtacactttgcatgggtggattttttagtatatgaattctacctcaataaagctgtttagagttcttattttttt aaagaagaaaaccctccacctatgccatatttttcagtgagttccagaaaaagaatagatggtttacattcaaggagaaa ttggtttctcctccctttcatattcaaatgctattagtgtaaccagagaaaggaaaggaacttttataggtttatcaaat atatacagccaattctaacaaaatacagttgtaaagtaccggagaaagttaaaattaaatttgacatcaatctgatccct ggagattacttcagttaatggcttgtaaattctaaatgtaattgtatgcatgtctatgtttgtgcagatgccggctcatt gttccggctcccgtttgtctctctgctctctccctttaagaaagcactttattcattctcttggattcctctatttgata ttgaaataatttcaaatttacatgtcttgttttaatctctgtcccaagagacactagaaggagcagaagcagaagggaga agtggctgagactgcagtgattactgaaggagggaggccgaaagtggagacagttctttctcaggaaacagaatagcaag tcacctgctgagacttgggggttggaatgctgaagtggggctaaggagacagatgcagattggaaggtagcaaatggctg aggaccaggagagagagtgattgttcaaacattggctggaagattatcttccatcatctgcaaccacctgtaattttgtt cccactaactcccaaggagtctccagaccaaggctcacatggggatgaatgaaggcctctacttcctttttcat aaggg aggcttcatttgcatatgttcacccagtttgtagcatcatccacagtttccaataggcatgcatgatctcatgtgggcag acagtgtgtttctgtggttgactagaggaagccagggagacatttgctactgagcatggctagtatctgtgtgtgtgaga gtgagtgtgtgtgtgtgtgtgtgagagaaagagagagagtgtgtgtgtatgaatttcgtttcaaaatccatatgacacct acagatgttatcatgttgtctattgagataaagaattttggagttcttttaatcacaaatatggaaaatgttataaaacc ttcccaaaggcaaatctgaacactaagatgtgttgtgatgccaaagactctgctttgaaggagaaaaggaaacaccttca cctaccatcagtgttctgcaagacagtgacatctttcacaaatgcaacgtctccagcattctcagccaggcacctaaaat gttccagaaaatatacacataattacagaagagaaactagtggggctttcataaatatttgtaatatgcattccaaaaac tgaaatatggaagtaaacatctaaaagacaactatttctaggaatttactgtttacagcggcagattgaacacaggtgta cctgccctccttttaaaaccctatataaaagacattacaaaaccaagaaatctaaagatatgcgacccaggaaacaggca atctaacatgaagtaagacaaaggaaagcaccaaaataatggtcaacaggacccccaggaccacagatgtgcaggcggcc tacacagcaaccagtccaaactgcagcaggaagatggatgccttctggagcagcacttccaagtaaatgatgaaactgtg atagcacccagagagagagagagagagagagagagagagagtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgt gtgtgtgtgtatgcatgttgttaggagatttacattactggcagacagtttggggatgagatagtgatgtgtttttttaa gtgcagaaaattaagcaaataagaaaagacatttatgaactccagagtaaacaaaaagtttgtacaataagggaaatata atatgagaataacgcttacacagtcataagtactgaatatgacattagcgtgttgggtgctgaagagagttgaagtctgt ggttgtgtggtggaaaaggtgctgggggcagtgtgagaggctagatcttcttctatactacagagtcagcagaaagttaa aaattaagaaccagcattataaggatgatagaaataaaggggtatgacactggtttcagcttttaatgattttgctataa atttccccaatctagattctagatataatttaaacaaaagacaagggattttcttccagtataattaggaatattaaaat gtgggtgtttccagtgaactaataccttgctgcaggtctgaaaaaaaaaaaaagaggagcacatgcttctttcgggctct tatgagacatgtgttcagcatttctgagtagaatcacatttccatttgcaaatccttagtcccttaaagatatttttata cattcacaaaacatttttttttgttttgggtctttttttatgagccacttatatagcaaaagctacttttctgtcattcc attactggaacaaggctgttgaatttatattaaaaagttcagacaccctcagacacatgacgccatctggtcgtgaaatg tactcttggcaaatggaggaaaaggaacaggggaagatcctctctgcacccttcacactggtaaatagtgcccctgagaa gcaacacccggatgaatggtgctgtaaaacgtggggtgtggttacaagtcactaagtggttataacttatgaattctgaa aacttgttttttggcttatttttcacttcgttactggagaataacactgcaattctgccatctctttgccatttctaagg ccaaagtcagagaaaaagggaaacctaagccatagtcatgacctaggtgagaagaaaaggggcggcgatgggaaagagaa ttcttccccataaatggaattgtaggaagcacttaggataccacactctacccatttgattttcaggacgaggctattga ggcctactgctgttgatcttggctcaaagccacagggagaagcactgcggagctgaggtcagacagccctggtgccagcc tccactctctggggcggtgggtgtggtggggacagccctcactggggccacccatgagctgacccacaggatgaccccca ctctgctgtgacaggtcacatctggctccttagaactgcaatgctgacatgctgagggatgaggtaagtccccatcctga tggagctcagtcacagactcaccggaaagccccagtgtagccgtagtatctctcgttgctgttgggcacgcacttattct caccctgctcgtcgccaatacacagagcacagagattagatctcgggtcagacccaggggcacagctttgactgaaatat tcatctggagagaaggaacacggggagtcagctcttcaaacctgagtccacacaagcaacctttacctaacagccgatgc agggtggtttcagttcattagacttcccaggacagcaatctagatagaacacactcaccatcacaaagcaacatgttgtc accaacataggacccaccagaaaagcttcattcagactgtaggcacagatggacacccaactaaggctggggatgagagc tgtggctgcctggagggtcccgtcatcacagccttgagctggggactcagctcatgaccgtgatggctgtgtgcagcaga gcctgtgagttgcctagtccaggatctgattttgtttttatcagtaatggaaaccctgctttgtatctgggtgcttggcc ctttggtataaagactagacttatcagactccctggggctcatatggccatatgggtagctataggccagtgaaatatca gcaggagtgttgggcgccagcttctcagaaacatccttgaaagacaattggtacatgccttttgccctttcttctccttc tctttcttcatcctgcacatagaatgcagaagcagggactggacttagagatgcaatgtgggccatgaggtgaccttgag catgaaagccacacaaatggcagagtagccaaatgattaaagcccaggttccagaccccatattgtcttcataccagccc taggcaaaccacctctggactacatgacacagaaattaacttctgtcttgtttaagcctctactatttcaggagttttct gttccttgcagctgaacctgatctgaattcgttcattgtgtgatttaacccaagaaagaataaacaaaggtgacaagaaa gctctgccccactgagcaaacgtcacccattatcagactcccactgctgctggaagagccacactatgtgtcaacctcag gaaaagctgggagttcccattccatcctggcagtttccctacagctcagaggctgccatggagctggtgaggagcagagc cacgtgaaagctgcctgccccggccaggatcaaaaacccatgcagtggagcccctgccctaggagacgcccatacaagaa gggagtcacattgaggatgtgctacacaccatgccacggggcccacagcaggcagggtgtggctgatgctgactaggatg agtgtggggtgtggtggggagagaaaactgcagaagcaggtggagccaggctcttgaggtcttattcaggctccgttgca gtgtagagtaagcgtcagttttgcttagtaacaggagtcacctttcatgaggcaggcagacatctttccccaagctggga agccagagtttaagaggaatttaggtctggagctccaagaggtaaaaagcatttgcacatcttggaacttgcatttattc ttagggtgcagcgaaataggcagatattccaatctttaatcttggggtggggtgaatggggcatgggaagtgctgtgcag ggaaacccccagtgcacccacgcctccagggggcagccacagggagaatttccttatgctggaagaggcctgcaggccac tatcagcctgcaaatcccctcccctcccttccctaaggttccacagcacaatatgcctaccctccagggtggcccaccca ccgcacctttggaactccttaccaaatttgcaggagcccgtctggttgaagagcaggcccatggggatattccagcctgc agtcctgtccacggcggtgtggcaggacttcttgcctttcacagagttccaggtaaggctagtgtctgatctcctaacca ccgccacagcaagatatcctggcataacagatgacagaaaaacaagtcttaacctccaggaggcctggcacatggattcc agtggagctgtctacagcccaggccaaaacaggccaagaagcaacaccaggcaatgattccctcaaagaactggcctttt taggtagaccgagaaagcataagctgctgccttatgttaaggtgagattgatgaaataaaacagtaagaaaagctgatta ttttagtgattacaggggactgtcttcaaccagccacacaatgtccctgagttacaaaccagcaatgcatctctcagtgt aagcttctacagcaacaaacactataaacaacaagagagaccccaacagtgcataaatcaccaaccacagtgtgcatcag gcaagagcaccaacatccagccagctaacggctgtgtgggtacaggggcacatgtccccagggactgccctgagctgagt ctgaacccaccctgcactggttgaactcaacatggttgccgttgtcctcctgagagaatgcatctgacagacacccacca agggcaagtcttttctgaaactgagcaagcaccagctctggtgggcaggaggagtggtgcacagagcactgggacacgag tcccaggtcacgaggacccggggtcaagaccaggatctaccacagtattacctatggctgtgagtgagatcctgggcact tggggactctcggtgccactgtttcctcatccccatgaggtggggaagtagcaccccccattccatgaccatgacaaaat gagggactatatggatgttctttgccaagtgtgaaggtcaatataaacattaattagaactattcctctgtgaattattt gcacccttaaaattattgctcctagaagccctatagcttctagggctgcaattctttctgttttttttacagttcctgcc acttcctcttccagcaacaagaacttatccttgaccctgaaagtggctaatgqcaactcaccttccacaggtctatccac acagttaggatcagggtcactgctttgttgggattctgaaagaataaagacaagccagacatcattatccattcagatgt agtgagaagccacaaactcttaaatctcaatgatgcagaatcaaatccaaagagaccgtcccagcagttccatgcaggag aaatgcgtctatatgttcaacaaaagacatggcacagagattcacagctgcattattcaccacagccaccaactggaaac tac caaatgcccatccacactcaaatgatgaataatcacagtagactcacacagcgacgagactgaacagtctacaact acacacttaggtggatgaaaagcataacgatgagcaagagaaaccagacataaaaaaacacatgctgtgtaattccttta acatgaagtttaaaacataggcaaacttagatctgcgaccttagaagccaggagagaggcttcccttgcaggagtaaggg ggcgggggacaggaggacataaggggcttctgaaacttgcagtgtttgttctgggcccgagagcatggactgtacagtgt gtgaagtgccatgagttgtacatttatgtgcacttttctgtttgtatgttataattcactgagatcttctggaaaattaa gaagataaaaccaacctgtcccttgttaattctcaacacaataggctttgtgggtaacacggcccctttcatttcttctt tccctgattctcccttttgaatgtatctgttcatcataatgtttcacctgcattcaccgaatgggattactcatagcccc actcccatgacccagagggaatataccagaggatgctaactccacttactgtagttctctgccaggacaggcaccaaacc acatttgcctgcagtgtacacata cctccatccaaactcatggcatcagcttctcctttctgcaaagacagagcagatc tccagcaccacagtgaggctgcatcccgtcctgcctgtctatatagctctctgagagaatggttttctgtcaggtgacca gtgaaacagcagaaagagatggactattcaaactgagcagccagaggaaacaccgtgtgcaccactaattctctcccagc cctgcctactttctgggctgtcaattcaactggaaagaccaggcacaggttgcactaatcctctgtcctctgagcaaaac cttttctgtgtccctggcactttggggacaccttcctggagcagtctcactgactgaggacacagatgggaacagctggc ctcatctaatctgaactcattagcactccactccaagcgctacacagaagttgtccaacacataagctgaagtcgtcata ttggcccaccaccagaatgaacaagtccaggctacaacacaggatcatggactcatcagtagtatgaaacttcctctttg acccagtaatatttttacaactatattaaaaatagagaagtggacaaagatttctactcaagaatgctcaccacagggtt attgataatagcaaagtaagggacaaagaggaatgggggcatgactaaactgagccatattcacataaaagatatcctgg aagcatgtttaaaaaatgttttcgtccgagtgctgtggctcacacccgtaatcccagcactttgggaggccgaagcagga agattgcttgagcccaggagttcgagacgagcctgggcaacaaagcgagaccctgtcgctacaataataataataataat tatgcaggtgtggtggcgtatgcctgtagccccagctacttgggaagctgagatgggaggatcacttgagcccaagagtt ccaggctgcagtgagatgtggtcgcaccactgcactccagcctgggtgacagatcaagaatctgtctcttaaaaaaaaaa aaattaatgctttccaagagtaaatattcatgtggaagaatgcccattatacgctgtttagtgaaaagggcttaaaaacg acatactgcaacacttcattattgttgcatgcatatctgcagatgtgcagagaaatactggaatggagaattagccagac tttaaccatgtctgtccctctgtgtgagatcacaggtggtttggggggtttgttgttgttttgttttaacataatacctt tccatattttccaaattccttataataatcctgagttgttcttataaccagaggagtgggaaacccacagtaaactgctt tttgaaactaaaatgctttctggccctgagcacacctctccaggcatccctgcctcacccaggcccccgtggcctctttg actgttgacttcactttaagcagatgcccaggccctaggtcttccaccgggcccaccgcccgcccctgtgatggagctcc ctaccagcaccagggcgatgcagtcctctgtggtggaggccgaggagcaggtcacgctgccttcgctcaagccactccac tggttacacttgcgcagctcctgctcgcccaccgcacaccacacgacccgcgcacgccgggcagccacttcctcctcacc tgccagagggaagaccgcaggtggctgggcaacctgagctttgccaggttgtccaacctccccagagccagggtcctgcc cagactctccctggaacaggagctacagtacatgtgtggacatgtggacccataccctctcctcctccacttctcagctc caagccccttcttcaggtccacagagctccctgtgtttcccacttctgttcctttggagaagttccctggcttctaatct atccattaatctttagagtcaggaggcgcctattgtctctgtctctgaggataaacgctccatgacccagagaccagtga cagtcccaagagatggcctaggggaccttgagcccaaccctgacttcccctaacgcctgcaatcaccaccaataactacg gtgcagcctctgggttcccccagactcccacccccagccccccagtagagaaggagccatagctgagttcccccaccatg gtgtccccaactaagttcaaggtctgggcctgggaagtgtgggtaaatccaggcccccggattcatccaggaggggtcct ggctatctttgttcatgttcatgtttctcacttaataggaggcaaactgatttttctgccaggcctggggagcctgacgt gcactgatcaggtggccagactattcttttagagacacctgacctaatccacagaagacactcacacctgcatcaaacct ccacgatgaccccacagtgtctgggaaaaggagtgaccgccacaaagtagggccacctgctgggaagtagaagaccacac caggcggacctcaggaccctcctgggctcactcacttttcctcaagttctggatggcagtgaagtagccggagccaaggt acagcccagaatctatcctcgggggcaccctcgaaaacccaatggcagagtccttgaacagcagatctttctgcccacta ggggagccaaagagctggaatttcggtgacttgtcctttccaaacttttcctaattaagaaaaaatagaattatggtgtc aatggtaaatagggaggaaacaaaaaaatgatgttaaaaaagagtatctggagctttgggatcattctaactgagagcag gagcctcggttgagaccctcctgcagagggacttgtgccatctcggagacccaagctcagctatggctcattctttgaag agttgctgaggtccaagcaccttagggccctgagaagattgcatcgaccaccccctgcttctgctcccatcataagacgc tgtcagcccgtgtgacagaagagtttcattgcttctgctgtccacagtacagcctgggcaagcagcccaatgcattagtg tgctatcctgcagcaaagctacaggacttctggagtggcagaagtcagggaagtaagaaaccttgctccctgccccccat atccaagcaagtggggaggaccgtgggtgaagatacctgtgcctggcggagaagattccagatggcatcctccttgccat tcacacttcgtgccacaacggcatgagaagggacccgggccagatggcagtctttgaacttgtccactggcttccgagtg ttgtctgggcagagtaactcatactcgtccctttcagcctcgtctgacaggtcctctgcagggaaggtgaggtgggaggg agtctagataagccgactccagcagtaacctcgagctatagttccccttctccctatagaattttgagcttggggagata gctgacaaaactgagggtcagaaaggcaggggtttgctccagaacactcagaaaggtaaaggtagtgccccaaaagcctc agggggcagccgaggtgtgatcctcatcctaaatcacttaggccaccctggggttcccgtgcagctgctgcctggcaggc cagagaggccaaaccagacccgtctgtttctgcggcatctctgcctggaaaagtcactttgcagagacaagctcaggggg ccaccaagggttgctcccttactcacatctctgggaagaataaaaatgacaaaaatgttaacaaggcagggaataaggca ggaaggtgagacactttccaacactgagtatatcaaaagaaggggaagaatggttttatgaatgagttcaggcaaatgtg gaatatcatatataagttgcttcagaatgtgtaaagtgaaaaaaatcttgcccgagtcattttatgagattagtacaacc ttgatgtcaaaatcagaaaaagtataggagggaagaattaaaagtttattttacttacgaacataaatgcaaaatttgta aataacgtactaactaactcaatctcacagagtatttaaaaagctaatagattggaatgaaggtttaccagtgtattcca ttaacaaaagaatggctgaacatcaaaaaaactaaagtaatctgcatttaatggcagaaaaccatgagatcgtcttcatc ttaatagatgcagaacgattgtttatgtgttcaacatctatttgtgtgtggtttttttttcagcctcagaaaaatagtaa tagatagaatcggtaaagtttttttgtttgttttgagacggagtctcactctgttgcccagcctggaatgcagtggtgcg atctcagctcactgcatcctccatctcctggagtcaagagattctcttgcctcagcctcccaagtagctgggaccacaag cgcacgccaccaggcccagctaatttttgtatttttaatagagatggggtttcaccatgttggccaggctggtctcgaac tcctgacctcatgtgatccacccgcctcagtctcccaaagtgctgggattacaggggtgagacaccacgcctggccataa gttattggcttgataaatgccattaatctacagcaaaaaccttactaaaagaagaaaatgtagacattcaccgcaaaatc aggaacaaggcaaggatgcccactgttacaatgccagcacaattctagatatccagatcacacaatttacaaaagaaatg tgagatataaacactggaaggaaaaagacacactcttatttaaaaagatgata gtcatctacaaaaaaccaatgaaac caacagaaactaataaaactactcagaggagtaacaagttataagagcaacctacaaaaatcagatgttatcctcattaa caataaccaaatagaaaccaatatggactataagatgttacaatagcaactaaaaccattaagtagctaataattagcct cccacaaagacacatcagacccacaaaggaaaaattttagttctatcaaagaaactaaaaagaggtgtgatcaaatgggg gagatttagcatcaccatggactggacaacttaatgttataaatatgctgatttttcatggaacaatttaaattcagtac aattcgaatcaaaattaaagtatgattttttccagaaattcaacaaaataattctgaagttttagctgagtatatttgaa aaggaataataaagtgagaggggagagggagctctctctcattctctctctcttcctctcactggctctctctctttctc tccaccagatagtaagacccattggtaagccacagtaacaaaagcagaaaaaatgcaaatacaccaatgaaataaaatag ctcagaaactggtccacttggatatatacaaacttggtgtagaattggcttcacatatggcagaaaaaatatactttttt tattgtaaggtaaattgcctcactgtaaaggggataaaatgctaaagccaaatctatatctgactttctaggtagagcac atataaatagatgaggaaggggatcttcaaatcttattttaggaaataattatgatttgggtgtgaagaagggcatcttt gaaatatctcaaaactacaaaccaacaaggtgaggcttgtggatttgaccttatcaatatcaaggatttttgatcaacag agactaccgttgtcagatttttgactgagaagaggttttactaaagtttaaaatcagcaatagtttgatacctagataga aggaacttctgtccttgaatcaaaatcatgcagaaacaaggtgtgaaactcaatttaaaaagtagtcaaatgtcacaaaa taagaaagggaagcccaaacggctagcaaatatgttgaaatgatcaaactcaccagctgtcagagaaatgaaaattaaaa a aaaacgaactatctattgcattacaaccatcattcggacaaaaagtatgaaagtcaaaaatacttctaactgaagttg tggggaaattagaacacttgcagagtgtcattccagacagcagcttggtgatcctgggtgcatgtggggtctgtctctgg tggccctgggtgcatgtggaggtctgtttctggtggcctctgatgaatgcggggtctgtctctgatggtcctaggtgaat gtgggtgttgtctctttctctggtggtcctgggtggatgtggggtgtgtctctgatggtcctgagtgaatgtgggtgtct gtcactttctctagtggccctgggtggaatatagtagccctgtctctattggtcttgcatgaaatgtagtgagcttatgt ccactagtcctgggtgcagtgtgtttagcctctacatactcatcaactgctttattataagtccaggagggacgctgtcc agcaggtaagtaaggaacacaggtgaaggtatcagtcgtgtggctgcatgtggtagaggaaaagagagcacaacctctgt ccatcactatggtgacagagaagtaaaaggtggatgtattccacggaacactcctcaactgttaggacccctgagctaga catgtatacaacaataccgataaacctctaaaacaaaatgctgagcagaaaacccaagtagcaggatttctaatgctcac taaaacctctatgaacccagaaaccggaaacacaaaccagcacaatctgttctgcatgagcacatgtgtcttggaggact ggaggacgcattgccaagcacctaggcatgggtgtctatgaggggaagagaaaggcagtaggcacaggaggtttgaagaa aactgatcatttaaaatatgaaagatcataaaatcagagctgtgccctgtaggaatcttgaaaatggtctgccatgaact taggaatctaattagctcaaaggtcagagtcatgatcaagtaagataaaaggggtcagtacccacggctcattaccctgc tcttaccaaacactgtgctctctctgataaaagccacgtctccagccccgtctctcagacacctgtgaaaagagaaacca tcaggggtaagcacaggcagccctccccagcccctccctgtggaacagtagccctggcactcagcatctatgggtttcta (SEQ ID N0:12041) gagctcagaaattcaagaccagcctgggcaaggtagagagacccccatgtctacaaaaaataaaaaatgattagtcaggt gtggtggcccgcacctgtagttccagctactcaggacgctgaggtgggagaatgactcgagcccgtgagttgaggctgca gtgagccgagatcacaccactccagcctaggcaagagtgagaccctctctcaaaaaaaaaaaaaaaaaaaaaaaaaaaag aaccatcaaaatgttttgcacagcagtcacgccattttacatttctgccagcaatgtgcaccaggcttccagtttcttca catcttcactaactcttatttcctttgctttaaactctaaccatcaaagtaggtgtaaagggtatctcactgtggtttga tttgcatttctctaatgactaatagtgttaagtatcatttcatgtgcatgttggccatttatatgtcattggagaaatgt ctactcaaaccgtttgctcatttagaaacttaggtaggttggtctgagtgcagtggtgtttaaaactaatttttttttga gacaaagtctcactctgtcgcccaggctggaatgcaatggtgagatcttggctcactacaacctccatctcctgggttca agcaattcttctgcctcagcctctcaagtagctgggattacaggcatgcgccaccacgcctggctaatttttgtattttt ggtagagacgggggtttctccatgttggccaggctggtctcgaactcttgacctcaggtgatccacctgcctcggcctcc acagggctaggattagaggtgtgagccaccgcaccaggccgtttaaaactaatggagcacaaccagttaccaatatcttt gttccttctccactccctctgcttcaacttgactagcctaaaataaataaatttaaaaaactgggcacagtggctcacac ctgtaatcccagcactttgggaggccgaggcaggaggattacttgagcataggagttcaagatcagcctgggcaactagt gaaaaaccatctcaaaaaagaaaaattagccaggcatggtggcatgcacctgtggtttcagctacttagagcagaggtgg aggatcgcttgattctggagttcaaggttgcattgagctgtgatcgcgccagtgcactctcgcttgggtgacagagtaag accttgtctcaaaaaatttaaaacaaaacaaaaaaaactggttatttgtctttttattggtgaattataagagttttaaa aaatatattctggaaacaaatcccttattagagatatgatttgcaaatattttctccaattttttttttttttaaagaca aagtttcactttgtcgcccaggctggtcttgattcctggcttcaagagatgctcttacctccacctcctgaagcccaaag ggctggaattacagccagtgagcctgcacccagcctccaattctttagattttacattttagaaccaaaatgggttaaat acactgttctgtaatctgctcttttctttaatagtagttcatgtacatctttcaaggtccagagaaagctctcactttct ccccgttttatttttccttccctcattctttttcactgctgcatagcattccattgtaattttgccactgtttattagac cagtcctctgctgagctttacagagcccttagttggatgttagtgagaaccatgacagcagtgagactgtcatctccctg acatgctgtcagcttttggatgatgtgaaaatgcaagcaggcacaggaaatgtctctaacttgcttacacttcctccctg aaccctgcggtttcacaactcctgcaggcacacctccctccccgcctgccagtgtcaccagcctgttgcctctgtgagaa agtaccactgtaagaggccaaagggcatgatcattttcctctttcaccctgtctaggttgccagcaaatcccacgggcct cctgacgctgcccctggggccacaggtccctcgagtgctggaaggatgaaggattcctgcatcactgtgatggccatggc gctgctgtctgggttctttttcttcggtaggcaagggaggaggcaggggaagggacatgtgtctgtgaccagagaaactg cagggcttggtgcagctggagtaaacaaggagctgccccctaaaagtgggattggccttagggatatggggccccaggga tcttggaaggagaaaggggagagcggggaaataaaag (SEQ ID NO:12042) gatcttggctcactacaacctccatctggtgggttcaagcaattcttctgcctcagcctctcaagtagctgggattacag gcatgcgccaccacgcccggctaatttttgtatttttggtagagacgggggtttctccatgttggccaggctggtctcga actcttgacctcaggtgatccacctgcctcggcctcccacaggctaggattagaggtgtgagccaccgcaccaggccgtt taaaactaatggagcacaaccagttaccaatatctttgttccttctccactccctctgcttcacttgactagcctaaaat aaataaatttaaaaaactgggcacagtggctcacacctgtaatcccagcactttgggaggccgaggcaggaggattactt gagcataggagttcaagatcagcctgggcaacatagtgaaaaaccatctcaaaaaagaaaaaattagccaggcatggtgg catgcacctgtggtttcagctacttaggagcagaggtgggaggatcgcttgattctgggagttcaaggttgcattgagct gtgatcgcgccagtgcactctcgcttgggtgacagagcaagaccttgtctcaaaaaatttaaaacaaaacaaaaaaaact ggttatttgtctttttattgttgaattataagagttttaaaaaatatattctggaaacaaatcccttattagagatatga tttgcaaatattttctccaatttttttttttttaaagacaaagtttcactttggtgcccaggctggtcttcattcctggc ttcaagagatgctcttacctccacctcctgaagccccaaagggctggaattacagccagtgagccactgcacccagcctc caattctttagattttacattttagaaccaaaatgggttaaatacactgttctgtaatctgctcttttctttaatagtag ttcatgtacatctttcaaggtccagagaaagctctcactttctccccgttttatttttccttccctcattctttttcact gctgcatagcattccattgtaattttgccactgtttattagaccagtcctctgctgagctttacagagcccttagttggg atgttagtgagaaaccatgacagcagtggagactgtcatctccctgacatgctgtcagcttttggatgatgtgaaaatgc aagcaggcacaggaaatgtctctctaacttgcttacacttcctccctgaaccctgcggtttcacaactcctgcaggcaca cctccctccccgcctgccagtgtcaccagcctgttgcctctgtgagaaagtaccactgtaagaggccaaagggcatgatc attttcctctttcaccctgtctaggttgccagcaaatcccacgggcctcctgacgctgcccctggggccacaggtccctc gagtgctggaaggatgaaggattcctgcatcactgtgatggccatggcgctgctgtctgggttctttttcttcggtaggc (SEQ ID Nθ:12043) cagggcagactggtagcaaagcccccacgcccagccaggagcaccgccgcggactccagcacaccgagggacatgctggg cctgcgccccccactgctcgccctggtggggctgctctccctcgggtgcgtcctctctcaggagtgcacgaagttcaagg tcagcagctgccgggaatgcatcgagtcggggcccggctgcacctggtgccagaagctgaacttcacagggccgggggat cctgactccattcgctgcgacacccggccacagctgctcatgaggggctgtgcggctgacgacatcatggaccccacaag cctcgctgaaacccaggaagaccacaatgggggccagaagcagctgtccccacaaaaagtgacgctttacctgcgaccag gccaggcagcagcgttcaacgtgaccttccggcgggccaagggctaccccatcgacctgtactatctgatggacctctcc tactccatgcttgatgacctcaggaatgtcaagaagctaggtggcgacctgctccgggccctcaacgagatcaccgagtc cggccgcattggcttcgggtccttcgtggacaagaccgtgctgccgttcgtgaacacgcaccctgataagctgcgaaacc catgccccaacaaggagaaagagt^'gccagcccccgtttgccttcaggcacgtgctgaagctgaccaacaactccaaccag tttcagaccgaggtcgggaagcagctgatttccggaaacctggatgcacccgagggtgggctggacgccatgatgcaggt cgccgcctgcccggaggaaatcggctggcgcaacgtcacgcggctgctggtgtttgccactgatgacggcttccatttcg cgggcgacggaaagctgggcgccatcctgacccccaacgacggccgctgtcacctggaggacaacttgtacaagaggagc aacgaattcgactacccatcggtgggccagctggcgcacaagctggctgaaaacaacatccagcccatcttcgcggtgac cagtaggatggtgaagacctacgagaaactcaccgagatcatccccaagtcagccgtgggggagctgtctgaggactcca gcaatgtggtccatctcattaagaatgcttacaataaactctcctccagggtcttcctggatcacaacgccctccccgac accctgaaagtcacctacgactccttctgcagcaatggagtgacgcacaggaaccagcccagaggtgactgtgatggcgt gcagatcaatgtcccgatcaccttccaggtgaaggtcacggccacagagtgcatccaggagcagtcgtttgtcatccggg cgctgggcttcacggacatagtgaccgtgcaggttcttccccagtgtgagtgccggtgccgggaccagagcagagaccgc agcctctgccatggcaagggcttcttggagtgcggcatctgcaggtgtgacactggctacattgggaaaaactgtgagtg ccagacacagggccggagcagccaggagctggaaggaagctgccggaaggacaacaactccatcatctgctcagggctgg gggactgtgtctgcgggcagtgcctgtgccacaccagcgacgtccccggcaagctgatatacgggcagtactgcgagtgt gacaccatcaactgtgagcgctacaacggccaggtctgcggcggcccggggagggggctctgcttctgcgggaagtgccg ctgccacccgggctttgagggctcagcgtgccagtgcgagaggaccactgagggctgcctgaacccgcggcgtgttgagt gtagtggtcgtggccggtgccgctgcaacgtatgcgagtgccattcaggctaccagctgcctctgtgccaggagtgcccc ggctgcccctcaccctgtggcaagtacatctcctgcgccgagtgcctgaagttcgaaaagggcccctttgggaagaactg cagcgcggcgtgtccgggcctgcagctgtcgaacaaccccgtgaagggcaggacctgcaaggagagggactcagagggct gctgggtggcctacacgctggagcagcaggacgggatggaccgctacctcatctatgtggatgagagccgagagtgtgtg gcaggccccaacatcgccgccatcgtcgggggcaccgtggcaggcatcgtgctgatcggcattctcctgctggtcatctg gaaggctctgatccacctgagcgacctccgggagtacaggcgctttgagaaggagaagctcaagtcccagtggaacaatg ataatccccttttcaagagcgccaccacgacggtcatgaaccccaagtttgctgagagttaggagcacttggtgaagaca aggccgtcaggacccaccatgtctgccccatcacgcggccgagacatggcttggccacagctcttgaggatgtcaccaat taaccagaaatccagttattttccgccctcaaaatgacagccatggccggccggtgcttctgggggctcgtcggggggac agctccactctgactggcacagtctttgcatggagacttgaggagggcttgaggttggtgaggttaggtgcgtgtttcct gtgcaagtcaggacatcagtctgattaaaggtggtgccaatttatttacatttaaacttgtcagggtataaaatgacatc ccattaattatattgttaatcaatcacgtgtatagaaaaaaaaataaaacttcaat (SEQ ID NO: 12044) ctcgccctggtggggctgctctccctcgggtgcgtcctctctcaggagtgcacgaagttcaaggtcagcagctgccggga atgcatcgagtcggggcccggctgcacctggtgccagaagctgaacttcacagggccgggggatcctgactccattcgct gcgacacccggccacagctgctcatgaggggctgtgcggctgacgacatcatggaccccacaagcctcgctgaaacccag gaagaccacaatgggggccagaagcagctgtccccacaaaaagtgacgctttacctgcgaccaggccaggcagcagcgtt caacgtgaccttccggcgggccaagggctaccccatcgacctgtactatctgatggacctctcctactccatgcttgatg acctcaggaatgtcaagaagctaggtggcgacctgctccgggccctcaacgagatcaccgagtccggccgcattggcttc gggtccttcgtggacaagaccgtgctgccgttcgtgaacacgcaccctgataagctgcgaaacccatgccccaacaagga gaaagagtgcccgcccccgtttgccttcaggcacgtgctgaagctgaccaacaactccaaccagtttcagaccgaggtcg ggaagcagctgatttccggaaacctggatgcacccgagggtgggctggacgccatgatgcaggtcgccgcctgcccggag gaaatcggctggcgcaacgtcacgcggctgctggtgtttgccactgatgacggcttccatttcgcgggcgacggaaagct gggcgccatcctgacccccaacgacggccgctgtcacctggaggacaacttgtacaagaggagcaacgaattcgactacc catcggtgggccagctggcgcacaagctggctgaaaacaacatccagcccatcttcgcggtgaccagtaggatggtgaag acctacgagaaactcaccgagatcatccccaagtcagccgtgggggagctgtctgaggactccagcaatgtggtccatct cattaagaatgcttacaataaactctcctccagggtcttcctggatcacaacgccctccccgacaccctgaaagtcacct acgactccttctgcagcaatggagtgacgcacaggaaccagcccagaggtgactgtgatggcgtgcagatcaatgtcccg atcaccttccaggtgaaggtcacggccacagagtgcatccaggagcagtcgtttgtcatccgggcgctgggcttcacgga catagtgaccgtgcaggtccttccccagtgtgagtgccggtgccgggaccagagcagagaccgcagcctctgccatggca agggcttcttggagtgcggcatctgcaggtgtgacactggctacattgggaaaaactgtgagtgccagacacagggccgg agcagccaggagctggaaggaagctgccggaaggacaacaactccatcatctgctcagggctgggggactgtgtctgcgg gcagtgcctgtgccacaccagcgacgtccccggcaagctgatatacgggcagtactgcgagtgtgacaccatcaactgtg agcgctacaacggccaggtctgcggcggcccggggagggggctctgcttctgcgggaagtgccgctgccacccgggcttt gagggctcagcgtgccagtgcgagaggaccactgagggctgcctgaacccgcggcgtgttgagtgtagtggtcgtggccg gtgccgctgcaacgtatgcgagtgccattcaggctaccagctgcctctgtgccaggagtgccccggctgcccctcaccct gtggcaagtacatctcctgcgccgagtgcctgaagttcgaaaagggcccctttgggaagaactgcagcgcggcgtgtccg ggcctgcagctgtcgaacaaccccgtgaagggcaggacctgcaaggagagggactcagagggctgctgggtggcctacac gctggagcagcaggacgggatggaccgctacctcatctatgtggatgagagccgagagtgtgtggcaggccccaacatcg ccgccatcgtcgggggcaccgtggcaggcatcgtgctgatcggcattctcctgctggtcatctggaaggctctgatccac ctgagcgacctccgggagtacaggcgctttgagaaggagaagctcaagtcccagtggaacaatgataatccccttttcaa gagcgccaccacgacggtcatgaaccccaagtttgctgagagttaggagca (SEQ ID NO: 12045) gagctcagaaattcaagaccagcctgggcaaggtagagagacccccatgtctacaaaaaataaaaaatgattagtcaggt gtggtggcccgcacctgtagttccagctactcaggacgctgaggtgggagaatgactcgagcccgtgagttgaggctgca gtgagccgagatcacaccactccagcctaggcaagagtgagaccctctctcaaaaaaaaaaaaaaaaaaaaaaaaaaaag aaccatcaaaatgttttgcacagcagtcacgccattttacatttctgccagcaatgtgcaccaggcttccagtttcttca catcttcactaactcttatttcctttgctttaaactctaaccatcaaagtaggtgtaaagggtatctcactgtggtttga tttgcatttctctaatgactaatagtgttaagtatcatttcatgtgcatgttggccatttatatgtcattggagaaatgt ctactcaaaccgtttgctcatttagaaacttaggtaggttggtctgagtgcagtggtgtttaaaactaatttttttttga gacaaagtctcactctgtcgcccaggctggaatgcaatggtgagatcttggctcactacaacctccatctcctgggttca agcaattcttctgcctcagcctctcaagtagctgggattacaggcatgcgccaccacgcctggctaatttttgtattttt ggtagagacgggggtttctccatgttggccaggctggtctcgaactcttgacctcaggtgatccacctgcctcggcctcc acagggctaggattagaggtgtgagccaccgcaccaggccgtttaaaactaatggagcacaaccagttaccaatatcttt gttccttctccactccctctgcttcaacttgactagcctaaaataaataaatttaaaaaactgggcacagtggctcacac ctgtaatcccagcactttgggaggccgaggcaggaggattacttgagcataggagttcaagatcagcctgggcaactagt gaaaaaccatctcaaaaaagaaaaattagccaggcatggtggcatgcacctgtggtttcagctacttagagcagaggtgg aggatcgcttgattctggagttcaaggttgcattgagctgtgatcgcgccagtgcactctcgcttgggtgacagagtaag accttgtctcaaaaaatttaaaacaaaacaaaaaaaactggttatttgtctttttattggtgaattataagagttttaaa aaatatattctggaaacaaatcccttattagagatatgatttgcaaatattttctccaattttttttttttttaaagaca aagtttcactttgtcgcccaggctggtcttgattcctggcttcaagagatgctcttacctccacctcctgaagcccaaag ggctggaattacagccagtgagcctgcacccagcctccaattctttagattttacattttagaaccaaaatgggttaaat acactgttctgtaatctgctcttttctttaatagtagttcatgtacatctttcaaggtccagagaaagctctcactttct ccccgttttatttttccttccctcattctttttcactgctgcatagcattccattgtaattttgccactgtttattagac cagtcctctgctgagctttacagagcccttagttggatgttagtgagaaccatgacagcagtgagactgtcatctccctg acatgctgtcagcttttggatgatgtgaaaatgcaagcaggcacaggaaatgtctctaacttgcttacacttcctccctg aaccctgcggtttcacaactcctgcaggcacacctccctccccgcctgccagtgtcaccagcctgttgcctctgtgagaa agtaccactgtaagaggccaaagggcatgatcattttcctctttcaccctgtctaggttgccagcaaatcccacgggcct cctgacgctgcccctggggccacaggtccctcgagtgctggaaggatgaaggattcctgcatcactgtgatggccatggc gctgctgtctgggttctttttcttcggtaggcaagggaggaggcaggggaagggacatgtgtctgtgaccagagaaactg cagggcttggtgcagctggagtaaacaaggagctgccccctaaaagtgggattggccttagggatatggggccccaggga tcttggaaggagaaaggggagagcggggaaataaaaggatcttggctcactacaacctccatctggtgggttcaagcaat tcttctgcctcagcctctcaagtagctgggattacaggcatgcgccaccacgcccggctaatttttgtatttttggtaga gacgggggtttctccatgttggccaggctggtctcgaactcttgacctcaggtgatccacctgcctcggcctcccacagg ctaggattagaggtgtgagccaccgcaccaggccgtttaaaactaatggagcacaaccagttaccaatatctttgttcct tctccactccctctgcttcacttgactagcctaaaataaataaatttaaaaaactgggcacagtggctcacacctgtaat cccagcactttgggaggccgaggcaggaggattacttgagcataggagttcaagatcagcctgggcaacatagtgaaaaa ccatctcaaaaaagaaaaaattagccaggcatggtggcatgcacctgtggtttcagctacttaggagcagaggtgggagg atcgcttgattctgggagttcaaggttgcattgagctgtgatcgcgccagtgcactctcgcttgggtgacagagcaagac cttgtctcaaaaaatttaaaacaaaacaaaaaaaactggttatttgtctttttattgttgaattataagagttttaaaaa atatattctggaaacaaatccct attagagatatgatttgcaaatattttctccaatttttttttttttaaagacaaag tttcactttggtgcccaggctggtcttcattcctggcttcaagagatgctcttacctccacctcctgaagccccaaaggg ctggaattacagccagtgagccactgcacccagcctccaattctttagattttacattttagaaccaaaatgggttaaat acactgttctgtaatctgctcttttctttaatagtagttcatgtacatctttcaaggtccagagaaagctctcactttct ccccgttttatttttccttccctcattctttttcactgctgcatagcattccattgtaattttgccactgtttattagac cagtcctctgctgagctttacagagcccttagttgggatgttagtgagaaaccatgacagcagtggagactgtcatctcc ctgacatgctgtcagcttttggatgatgtgaaaatgcaagcaggcacaggaaatgtctctctaacttgcttacacttcct ccctgaaccctgcggtttcacaactcctgcaggcacacctccctccccgcctgccagtgtcaccagcctgttgcctctgt gagaaagtaccactgtaagaggccaaagggcatgatcattttcctctttcaccctgtctaggttgccagcaaatcccacg ggcctcctgacgctgcccctggggccacaggtccctcgagtgctggaaggatgaaggattcctgcatcactgtgatggcc atggcgctgctgtctgggttctttttcttcggtaggccagggcagactggtagcaaagcccccacgcccagccaggagca ccgccgcggactccagcacaccgagggacatgctgggcctgcgccccccactgctcgccctggtggggctgctctccctc gggtgcgtcctctctcaggagtgcacgaagttcaaggtcagcagctgccgggaatgcatcgagtcggggcccggctgcac ctggtgccagaagctgaacttcacagggccgggggatcctgactccattcgctgcgacacccggccacagctgctcatga ggggctgtgcggctgacgacatcatggaccccacaagcctcgctgaaacccaggaagaccacaatgggggccagaagcag ctgtccccacaaaaagtgacgctttacctgcgaccaggccaggcagcagcgttcaacgtgaccttccggcgggccaaggg ctaccccatcgacctgtactatctgatggacctctcctactccatgcttgatgacctcaggaatgtcaagaagctaggtg gcgacctgctccgggccctcaacgagatcaccgagtccggccgcattggcttcgggtccttcgtggacaagaccgtgctg ccgttcgtgaacacgcaccctgataagctgcgaaacccatgccccaacaaggagaaagagtgccagcccccgtttgcctt caggcacgtgctgaagctgaccaacaactccaaccagtttcagaccgaggtcgggaagcagctgatttccggaaacctgg atgcacccgagggtgggctggacgccatgatgcaggtcgccgcctgcccggaggaaatcggctggcgcaacgtcacgcgg ctgctggtgtttgccactgatgacggcttccatttcgcgggcgacggaaagctgggcgccatcctgacccccaacgacgg ccgctgtcacctggaggacaacttgtacaagaggagcaacgaattcgactacccatcggtgggccagctggcgcacaagc tggctgaaaacaacatccagcccatcttcgcggtgaccagtaggatggtgaagacctacgagaaactcaccgagatcatc cccaagtcagccgtgggggagctgtctgaggactccagcaatgtggtccatctcattaagaatgcttacaataaactctc ctccagggtcttcctggatcacaacgccctccccgacaccctgaaagtcacctacgactccttctgcagcaatggagtga cgcacaggaaccagcccagaggtgactgtgatggcgtgcagatcaatgtcccgatcaccttccaggtgaaggtcacggcc acagagtgcatccaggagcagtcgtttgtcatccgggcgctgggcttcacggacatagtgaccgtgcaggttcttcccca gtgtgagtgccggtgccgggaccagagcagagaccgcagcctctgccatggcaagggcttcttggagtgcggcatctgca ggtgtgacactggctacattgggaaaaactgtgagtgccagacacagggccggagcagccaggagctggaaggaagctgc cggaaggacaacaactccatcatctgctcagggctgggggactgtgtctgcgggcagtgcctgtgccacaccagcgacgt ccccggcaagctgatatacgggcagtactgcgagtgtgacaccatcaactgtgagcgctacaacggccaggtctgcggcg gcccggggagggggctctgcttctgcgggaagtgccgctgccacccgggctttgagggctcagcgtgccagtgcgagagg accactgagggctgcctgaacccgcggcgtgttgagtgtagtggtcgtggccggtgccgctgcaacgtatgcgagtgcca ttcaggctaccagctgcctctgtgccaggagtgccccggctgcccctcaccctgtggcaagtacatctcctgcgccgagt gcctgaagttcgaaaagggcccctttgggaagaactgcagcgcggcgtgtccgggcctgcagctgtcgaacaaccccgtg aagggcaggacctgcaaggagagggactcagagggctgctgggtggcctacacgctggagcagcaggacgggatggaccg ctacctcatctatgtggatgagagccgagagtgtgtggcaggccccaacatcgccgccatcgtcgggggcaccgtggcag gcatcgtgctgatcggcattctcctgctggtcatctggaaggctctgatccacctgagcgacctccgggagtacaggcgc tttgagaaggagaagctcaagtcccagtggaacaatgataatccccttttcaagagcgccaccacgacggtcatgaaccc caagtttgctgagagttaggagcacttggtgaagacaaggccgtcaggacccaccatgtctgccccatcacgcggccgag acatggcttggccacagctcttgaggatgtcaccaattaaccagaaatccagttattttccgccctcaaaatgacagcca tggccggccggtgcttctgggggctcgtcggggggacagctccactctgactggcacagtctttgcatggagacttgagg agggcttgaggttggtgaggttaggtgcgtgtttcctgtgcaagtcaggacatcagtctgattaaaggtggtgccaattt atttacatttaaacttgtcagggtataaaatgacatcccattaattatattgttaatcaatcacgtgtatagaaaaaaaa ataaaacttcaatctcgccctggtggggctgctctccctcgggtgcgtcctctctcaggagtgcacgaagttcaaggtca gcagctgccgggaatgcatcgagtcggggcccggctgcacctggtgccagaagctgaacttcacagggccgggggatcct gactccattcgctgcgacacccggccacagctgctcatgaggggctgtgcggctgacgacatcatggaccccacaagcct cgctgaaacccaggaagaccacaatgggggccagaagcagctgtccccacaaaaagtgacgctttacctgcgaccaggcc aggcagcagcgttcaacgtgaccttccggcgggccaagggctaccccatcgacctgtactatctgatggacctctcctac tccatgcttgatgacctcaggaatgtcaagaagctaggtggcgacctgctccgggccctcaacgagatcaccgagtccgg ccgcattggcttcgggtccttcgtggacaagaccgtgctgccgttcgtgaacacgcaccctgataagctgcgaaacccat gccccaacaaggagaaagagtgcccgcccccgtttgccttcaggcacgtgctgaagctgaccaacaactccaaccagttt cagaccgaggtcgggaagcagctgatttccggaaacctggatgcacccgagggtgggctggacgccatgatgcaggtcgc cgcctgcccggaggaaatcggctggcgcaacgtcacgcggctgctggtgtttgccactgatgacggcttccatttcgcgg gcgacggaaagctgggcgccatcctgacccccaacgacggccgctgtcacctggaggacaacttgtacaagaggagcaac gaattcgactacccatcggtgggccagctggcgcacaagctggctgaaaacaacatccagcccatcttcgcggtgaccag taggatggtgaagacctacgagaaactcaccgagatcatccccaagtcagccgtgggggagctgtctgaggactccagca atgtggtccatctcattaagaatgcttacaataaactctcctccagggtcttcctggatcacaacgccctccccgacacc ctgaaagtcacctacgactccttctgcagcaatggagtgacgcacaggaaccagcccagaggtgactgtgatggcgtgca gatcaatgtcccgatcaccttccaggtgaaggtcacggccacagagtgcatccaggagcagtcgtttgtcatccgggcgc tgggcttcacggacatagtgaccgtgcaggtccttccccagtgtgagtgccggtgccgggaccagagcagagaccgcagc ctctgccatggcaagggcttcttggagtgcggcatctgcaggtgtgacactggctacattgggaaaaactgtgagtgcca gacacagggccggagcagccaggagctggaaggaagctgccggaaggacaacaactccatcatctgctcagggctggggg actgtgtctgcgggcagtgcctgtgccacaccagcgacgtccccggcaagctgatatacgggcagtactgcgagtgtgac accatcaactgtgagcgctacaacggccaggtctgcggcggcccggggagggggctctgcttctgcgggaagtgccgctg ccacccgggctttgagggctcagcgtgccagtgcgagaggaccactgagggctgcctgaacccgcggcgtgttgagtgta gtggtcgtggccggtgccgctgcaacgtatgcgagtgccattcaggctaccagctgcctctgtgccaggagtgccccggc tgcccctcaccctgtggcaagtacatctcctgcgccgagtgcctgaagttcgaaaagggcccctttgggaagaactgcag cgcggcgtgtccgggcctgcagctgtcgaacaaccccgtgaagggcaggacctgcaaggagagggactcagagggctgct gggtggcctacacgctggagcagcaggacgggatggaccgctacctcatctatgtggatgagagccgagagtgtgtggca ggccccaacatcgccgccatcgtcgggggcaccgtggcaggcatcgtgctgatcggcattctcctgctggtcatctggaa ggctctgatccacctgagcgacctccgggagtacaggcgctttgagaaggagaagctcaagtcccagtggaacaatgata atccccttttcaagagcgccaccacgacggtcatgaaccccaagtttgctgagagttaggagca (SEQ ID NO: 12046) ggaattccgggcccggtctttcctcccgccgccgccggcctggtcccggggactggcctccacgtccgactcgtccgagc tgaagcccagcagcactttgctgccagccgcgggggcggcggaggcgcccccgggccctcccaggaggctctctgggcca gaggccgagattcggcacaggcccccaggagtccgtaagtaggagaggtcgcccgagaccggccggacccccatccccgc ggccgccgccgccgctggtcccgcggctgcgaccgtggcggctgccgctggaaaatgtctcaggagaggcccacgttcta ccggcaggagctgaacaagacaatctgggaggtgcccgagcgttaccagaacctgtctccagtgggctctggcgcctatg gctctgtgtgtgctgcttttgacacaaaaacggggttacgtgtggcagtgaagaagctctccagaccatttcagtccatc attcatgcgaaaagaacctacagagaactgcggttacttaaacatatgaaacatgaaaatgtgattggtctgttggacgt ttttacacctgcaaggtctctggaggaattcaatgatgtgtatctggtgacccatctcatgggggcagatctgaacaaca ttgtgaaatgtcagaagcttacagatgaccatgttcagttccttatctaccaaattctccgaggtctaaagtatatacat tcagctgacataattcacagggacctaaaacctagtaatctagctgtgaatgaagactgtgagctgaagattctggattt tggactggctcggcacacagatgatgaaatgacaggctacgtggccactaggtggtacagggctcctgagatcatgctga actggatgcattacaaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaagaacattg tttcctggtacagaccatattgatcagttgaagctcattttaagactcgttggaaccccaggggctgagcttttgaagaa aatctcctcagagtctgcaagaaactatattcagtctttgactcagatgccgaagatgaactttgcgaatgtatttattg gtgccaatcccctggctgtcgacttgctggagaagatgcttgtattggactcagataagagaattacagcggcccaagcc cttgcacatgcctactttgctcagtaccacgatcctgatgatgaaccagtggccgatccttatgatcagtcctttgaaag cagggacctccttatagatgagtggaaaagcctgacctatgatgaagtcatcagctttgtgccaccaccccttgaccaag aagagatggagtcctgagcacctggtttctgttctgttgatcccacttcactgtgaggggaaggccttttcacgggaact ctccaaatattattcaagtgcctcttgttgcagagatttcctccatggtggaagggggtgtgcgtgcgtgtgcgtgcgtg ttagtgtgtgtgcatgtgt (SEQ ID NO: 12047) tggttaacgccagggttttcccagtcacgaacgttgtaaaacgacggccagtgccaagctaaaattaaccttcactaaag ggaataagcttgcggccgcttcgggtttccggaggggccggagggcgggcgagggcgtcacgtgcgcgccgcccgcgggc cggttggtccccgggcgggggaggggccgtgcgcagcctgggtcggggtcgggccggggtcggcacctgggacatccctg agggaagggccgggagcgggagcgccccagcggccggcgggcgggcgggcgagcggacgagcggcgcggagccggcccga ggcgcgcgccgagggagccccgtccccggtcgtgggggcaccgcccgcaggctctgcggggtgggcagctcccgggcctg ccatgagctctccgccgcccgcccgcagtggcttttaccgccaggaggtgaccaagacggcctgggaggtgcgcgccgtg taccgggacctgcagcccgtgggctcgggcgcctacggcgcggtgtgctcggccgtggacggccgcaccggcgctaaggt ggccatcaagaagctgtatcggcccttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctcaagc acatgcgccacgagaacgtgatcgggctgctggacgtattcactcctgatgagaccctggatgacttcacggacttttac ctggtgatgccgttcatgggcaccgacctgggcaagctcatgaaacatgagaagctaggcgaggaccggatccagttcct cgtgtaccagatgctgaaggggctgaggtatatccacgctgccggcatcatccacagagacctgaagcccggcaacctgg ctgtgaacgaagactgtgagctgaagatcctggacttcggcctggccaggcaggcagacagtgagatgactgggtacgtg gtgacccggtggtaccgggctcccgaggtcatcttgaattggatgcgctacacgcagacggtggacatctggtccgtggg ctgcatcatggcggagatgatcacaggcaagacgctgttcaagggcagcgaccacctggaccagctgaaggagatcatga aggtgacggggacgcctccggctgagtttgtgcagcggctgcagagcgatgaggccaagaacaacatgaagggcctcccc gaattggagaagaaggattttgcctctatcctgaccaatgcaagccctctggctgtgaacctcctggagaagatgctggt gctggacgcggagcagcgggtgacggcaggcgaggcgctggcccatccctacttcgagtccctgcacgacacggaagatg agccccaggtccagaagtatgatgactcctttgacgacgttgaccgcacactggatgaatggaagcgtgttacttacaaa gaggtgctcagcttcaagcctccccggcagctgggggccagggtctccaaggagacgcctctgtgaagatctctgggctc cggggtggcagtgaggaccaccttcacctt (SEQ ID NO: 12048) ggaattccgggcccggtctttcctcccgccgccgccggcctggtcccggggactggcctccacgtccgactcgtccgagc tgaagcccagcagcactttgctgccagccgcgggggcggcggaggcgcccccgggccctcccaggaggctctctgggcca gaggccgagattcggcacaggcccccaggagtccgtaagtaggagaggtcgcccgagaccggccggacccccatccccgc ggccgccgccgccgctggtcccgcggctgcgaccgtggcggctgccgctggaaaatgtctcaggagaggcccacgttcta ccggcaggagctgaacaagacaatctgggaggtgcccgagcgttaccagaacctgtctccagtgggctctggcgcctatg gctctgtgtgtgctgcttttgacacaaaaacggggttacgtgtggcagtgaagaagctctccagaccatttcagtccatc attcatgcgaaaagaacctacagagaactgcggttacttaaacatatgaaacatgaaaatgtgattggtctgttggacgt ttttacacctgcaaggtctctggaggaattcaatgatgtgtatctggtgacccatctcatgggggcagatctgaacaaca ttgtgaaatgtcagaagcttacagatgaccatgttcagttccttatctaccaaattctccgaggtctaaagtatatacat tcagctgacataattcacagggacctaaaacctagtaatctagctgtgaatgaagactgtgagctgaagattctggattt tggactggctcggcacacagatgatgaaatgacaggctacgtggccactaggtggtacagggctcctgagatcatgctga actggatgcattacaaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaagaacattg tttcctggtacagaccatattgatcagttgaagctcattttaagactcgttggaaccccaggggctgagcttttgaagaa aatctcctcagagtctgcaagaaactatattcagtctttgactcagatgccgaagatgaactttgcgaatgtatttattg gtgccaatcccctggctgtcgacttgctggagaagatgcttgtattggactcagataagagaattacagcggcccaagcc cttgcacatgcctactttgctcagtaccacgatcctgatgatgaaccagtggccgatccttatgatcagtcctttgaaag cagggacctccttatagatgagtggaaaagcctgacctatgatgaagtcatcagctttgtgccaccaccccttgaccaag aagagatggagtcctgagcacctggtttctgttctgttgatcccacttcactgtgaggggaaggccttttcacgggaact ctccaaatattattcaagtgcctcttgttgcagagatttcctccatggtggaagggggtgtgcgtgcgtgtgcgtgcgtg ttagtgtgtgtgcatgtgttggttaacgccagggttttcccagtcacgaacgttgtaaaacgacggccagtgccaagcta aaattaaccttcactaaagggaataagcttgcggccgcttcgggtttccggaggggccggagggcgggcgagggcgtcac gtgcgcgccgcccgcgggccggttggtccccgggcgggggaggggccgtgcgcagcctgggtcggggtcgggccggggtc ggcacctgggacatccctgagggaagggccgggagcgggagcgccccagcggccggcgggcgggcgggcgagcggacgag cggcgcggagccggcccgaggcgcgcgccgagggagccccgtccccggtcgtgggggcaccgcccgcaggctctgcgggg tgggcagctcccgggcctgccatgagctctccgccgcccgcccgcagtggcttttaccgccaggaggtgaccaagacggc ( ctgggaggtgcgcgccgtgtaccgggacctgcagcccgtgggctcgggcgcctacggcgcggtgtgctcggccgtggacg gccgcaccggcgctaaggtggccatcaagaagctgtatcggcccttccagtccgagctgttcgccaagcgcgcctaccgc gagctgcgcctgctcaagcacatgcgccacgagaacgtgatcgggctgctggacgtattcactcctgatgagaccctgga tgacttcacggacttttacctggtgatgccgttcatgggcaccgacctgggcaagctcatgaaacatgagaagctaggcg aggaccggatccagttcctcgtgtaccagatgctgaaggggctgaggtatatccacgctgccggcatcatccacagagac ctgaagcccggcaacctggctgtgaacgaagactgtgagctgaagatcctggacttcggcctggccaggcaggcagacag tgagatgactgggtacgtggtgacccggtggtaccgggctcccgaggtcatcttgaattggatgcgctacacgcagacgg tggacatctggtccgtgggctgcatcatggcggagatgatcacaggcaagacgctgttcaagggcagcgaccacctggac cagctgaaggagatcatgaaggtgacggggacgcctccggctgagtttgtgcagcggctgcagagcgatgaggccaagaa caacatgaagggcctccccgaattggagaagaaggattttgcctctatcctgaccaatgcaagccctctggctgtgaacc tcctggagaagatgctggtgctggacgcggagcagcgggtgacggcaggcgaggcgctggcccatccctacttcgagtcc ctgcacgacacggaagatgagccccaggtccagaagtatgatgactcctttgacgacgttgaccgcacactggatgaatg gaagcgtgttacttacaaagaggtgctcagcttcaagcctccccggcagctgggggccagggtctccaaggagacgcctc tgtgaagatctctgggctccggggtggcagtgaggaccaccttcacctt (SEQ ID NO: 12049) ctcgatcaaaccttttttttatggtacacaatagtcacagtacttttccatataaaacaggtttagtggtcttaatttag tttggcacatttaatacactcccatgaccagcatcccaaatgtacctatccgttttattttattgtctcagaattgtcag ttatttaataaattatgtaacttttttccttatgctcagatttgcacttctttctaaaactctgcccatccttaaagtcc cagattctccttgaacttttttttttgactttccaagtacatggaactcttcactctatcctgctatataaggtgacaga atttccactatgggatagatggagttcaattcctttgagtttaaaataatctaaatataattattccttatgccctgttt ttccctcacttttgtatccaaatctcttttcagacaacagaacaattaatgtctgataaggaagacaatgatgatgatca cttcaaaatgaattcaggattgtaatgtaaaattttagtactctctcacagtatggattctaacatggcttctaacccaa actaacattagtagctctaactataaacttcaaatttcagtagatgcaacctactcctttaaaatgaaacagaagattga aattattaaattatcaaaaagaaaatgatccacgctcttagttgaaatttcatgtaagattccatgcaataaataggagt gccataaatggaatgatgaaatatgactagaggaggagaaaggctcctagatgagatgggattttaggcatccgtgtctc atgaggaatcagttgtgtcactaggcaaaacagtaaaaaaaaaaacctccaagtgagtctcttatttatttttttcttat aagacttctacaaattgaggtacctggtgtagttttatttcaggttttatgctgtcattttcctgtaatgctaaggactt aggacataactgaattttctattttccacttcttttctggtgtgtgtgtatatatatatgtatatatacacacacacata tacatatatatattttttagtatctcaccctcacatgctcctccctgagcactacccatgatagatgttaaacaaaagca aagatgaaattccaactgtcaaaatcccccctccatctaattaatccctcacccaact tgttccaaaacgagaatagaa aattagccccaataagcccaggcaactgaaaagtaaatgctatgttgtactttgatccatggtcacaactcataatcttg gaaaagtggacagaaaagacaaaagagtgaactttaaaactcgaatttattttaccagtatctcctatgaagggctagta accaaaataatccacgcatcagggagagaaatgccttaaggcatacgttttggacatttagcgtccctgcaaattctggc catcgccgcttcctttgtccatcagaaggcaggaaactttatattggtgacccgtggagctcacattaactatttacagg gtaactgcttaggaccagtattatgaggagaatttacctttcccgcctctctttccaagaaacaaggagggggtgaaggt acggagaacagtatttcttctgttgaaagcaacttagctacaaagataaattacagctatgtacactgaaggtagctatt tcattccacaaaataagagttttttaaaaagctatgtatgtatgtgctgcatatagagcagatatacagcctattaagcg tcgtcactaaaacataaaacatgtcagcctttcttaaccttactcgccccagtctgtcccgacgtgacttcctcgaccct ctaaagacgtacagaccagacacggcggcggcggcgggagaggggattccctgcggccccggacctcagggccgctcaga ttcctggagaggaagccaagtgtccttctgccctcccccggtatcccatccaaggcgatcagtccacaactggctctcgg aagcactcgggcaaagactgcgaagaagaaaagacatctggcggaaacctgtgcgcctggggcggtggaactcggggagg agagggagggatcagacaggagagtggggactaccccctctgctcccaaattggggcagcttcctgggtttccgattttc tcatttccgtgggtaaaaaaccctgcccccaccggcttacgcaatttttttaaggggagaggagggaaaaatttgtgggg ggtacgaaaaggcggaaagaaacagtcatttcgtcacatgggcttggttttcagtcttataaaaaggaaggttctctcgg ttagcgaccaattgtcatacgacttgcagtgagcgtcaggagcacgtccaggaactcctcagcagcgcctccttcagctc (SEQ ID NO:12050) gtccaggaactcctcagcagcgcctccttcagctccacagccagacgccctcagacagcaaagcctacccccgcgccgcg ccctgcccgccgctgcgatgctcgcccgcgccctgctgctgtgcgcggtcctggcgctcagccatacagcaaatccttgc tgttcccacccatgtcaaaaccgaggtgtatgtatgagtgtgggatttgaccagtataagtgcgattgtacccggacagg attctatggagaaaactgctcaacaccggaatttttgacaagaataaaattatttctgaaacccactccaaacacagtgc actacatacttacccacttcaagggattttggaacgttgtgaataacattcccttccttcgaaatgcaattatgagttat gtgttgacatccagatcacatttgattgacagtccaccaacttacaatgctgactatggctacaaaagctgggaagcctt ctctaacctctcctatta actagagcccttcctcctgtgcctgatgattgcccgactcccttgggtgtcaaaggtaaaa agcagcttcctgattcaaatgagattgtgggaaaattgcttctaagaagaaagttcatccctgatccccagggctcaaac atgatgtttgcattctttgcccagcacttcacgcatcagtttttcaagacagatcataagcgagggccagctttcaccaa cgggctgggccatggggtggacttaaatcatatttacggtgaaactctggctagacagcgtaaactgcgccttttcaagg atggaaaaatgaaatatcagataattgatggagagatgtatcctcccacagtcaaagatactcaggcagagatgatctac cctcctcaagtccctgagcatctacggtttgctgtggggcaggaggtctttggtctggtgcctggtctgatgatgtatgc cacaatctggctgagggaacacaacagagtatgcgatgtgcttaaacaggagcatcctgaatggggtgatgagcagttgt tccagacaagcaggctaatactgataggagagactattaagattgtgattgaagattatgtgcaacacttgagtggctat cacttcaaactgaaatttgacccagaactacttttcaacaaacaattccagtaccaaaatcgtattgctgctgaatttaa caccctctatcactggcatccccttctgcctgacacctttcaaattcatgaccagaaatacaactatcaacagtttatct acaacaactctatattgctggaacatggaattacccagtttgttgaatcattcaccaggcaaattgctggcagggttgct ggtggtaggaatgttccacccgcagtacagaaagtatcacaggcttccattgaccagagcaggcagatgaaataccagtc ttttaatgagtaccgcaaacgctttatgctgaagccctatgaatcatttgaagaacttacaggagaaaaggaaatgtctg cagagttggaagcactctatggtgacatcgatgctgtggagctgtatcctgcccttctggtagaaaagcctcggccagat gccatctttggtgaaaccatggtagaagttggagcaccattctccttgaaaggacttatgggtaatgttatatgttctcc tgcctactggaagccaagcacttttggtggagaagtgggttttcaaatcatcaacactgcctcaattcagtctctcatct gcaataacgtgaagggctgtccctttacttcattcagtgttccagatccagagctcattaaaacagtcaccatcaatgca agttcttcccgctccggactagatgatatcaatcccacagtactactaaaagaacgttcgactgaactgtagaagtctaa tgatcatatttatttatttatatgaaccatgtctattaatttaattatttaataatatttatattaaactccttatgtta cttaacatcttctgtaacagaagtcagtactcctgttgcggagaaaggagtcatacttgtgaagacttttatgtcactac tctaaagattttgctgttgctgttaagtttggaaaacagtttttattctgttttataaaccagagagaaatgagttttga cgtctttttacttgaatttcaacttatattataaggacgaaagtaaagatgtttgaatacttaaacactatcacaagatg ccaaaatgctgaaagtttttacactgtcgatgtttccaatgcatcttccatgatgcattagaagtaactaatgtttgaaa ttttaaagtacttttgggtatttttctgtcatcaaacaaaacaggtatcagtgcattattaaatgaatatttaaattaga cattaccagtaatttcatgtctactttttaaaatcagcaatgaaacaataatttgaaatttctaaattcatagggtagaa tcacctgtaaaagcttgtttgatttcttaaagttattaaacttgtacatataccaaaaagaagctgtcttggatttaaat ctgtaaaatcagatgaaattttactacaattgcttgttaaaatattttataagtgatgttcctttttcaccaagagtata aacctttttagtgtgactgttaaaacttccttttaaatcaaaatgccaaatttattaaggtggtggagccactgcagtgt tatctcaaaataagaatatcctgttgagatattccagaatctgtttatatggctggtaacatgtaaaaaccccataaccc cgccaaaaggggtcctacccttgaacataaagcaataaccaaaggagaaaagcccaaattattggttccaaatttagggt ttaaactttttgaagcaaacttttttttagccttgtgcactgcagacctggtactcagattttgctatgaggttaatgaa gtaccaagctgtgcttgaataacgatatgttttctcagattttctgttgtacagtttaatttagcagtccatatcacatt gcaaaagtagcaatgacctcataaaatacctcttcaaaatgcttaaattcatttcacacattaattttatctcagtcttg aagccaattcagtaggtgcattggaatcaagcctggctacctgcatgctgttccttttcttttcttcttttagccatttt gctaagagacacagtcttctcaaacacttcgtttctcctattttgttttactagttttaagatcagagttcactttcttt ggactctgcctatattttcttacctgaacttttgcaagttttcaggtaaacctcagctcaggactgctatttagctcctc ttaagaagattaaaaaaaaaaaaaaag (SEQ ID NO: 12051) gagctcacattaactatttacagggtaactgcttaggaccagtattatgaggagaatttacctttcccgcctctctttcc aagaaacaaggagggggtgaaggtacggagaacagtatttcttctgttgaaagcaacttagctacaaagataaattacag ctatgtacactgaaggtagctatttcattccacaaaataagagttttttaaaaagctatgtatgtatgtgctgcatatag agcagatatacagcctattaagcgtcgtcactaaaacataaaacatgtcagcctttcttaaccttactcgccccagtctg tcccgacgtgacttcctcgaccctctaaagacgtacagaccagacacggcggcggcggcgggagaggggattccctgcgc ccccggacctcagggccgctcagattcctggagaggaagccaagtgtccttctgccctcccccggtatcccatccaaggc gatcagtccagaactggctctcggaagcgctcgggcaaagactgcgaagaagaaaagacatctggcggaaacctgtgcgc ctggggcggtggaactcggggaggagagggagggatcagacaggagagtggggactaccccctctgctcccaaattgggg cagcttcctgggtttccgattttctcatttccgtgggtaaaaaaccctgcccccaccgggcttacgcaatttttttaagg ggagaggagggaaaaaatttgtgggggggtacgaaaaggcggaaagaaacagtcattcacatgggcttggttttcagtct tataaaaaggaaggttctctcggttagcgaccaattgtcatacgacttgcagtgagcgtcaggagcacgtccaggaactc ctcagcagcgcctccttcagctccacagccagacgccctcagacagcaaagcctacccccgcgccgcgccctgcccgccg ctcggatgctcgcccgcgccctgctgctgtgcgcggtcctggcgctcagccatacaggtgagtacctggcgccgcgcacc ggggactccggttccacgcacccgggcagagtttccgctctgacctcctgggtctatcccagtactccgacttctctccg aatagagaagctacgtgacttgggaaagagcttggaccgctagagtccgaaagaactccgtggatattccagctttccca caagcactgatcattatgagccagttacttaaccgatctgagacactctcacctcctaaatagggatagatgatactaat ttgcaggttgtcattatgataagacaggatctgatcaatatatgtgaattgtttatatttggaacctttttattgagtgg aagaagttgttttaaatattctagtcagttctttcctgctcccaggaaagcccggattatgttttaagataagcaaaatg tcttaaaagtaagctgttttactttgaatttttccctaaatgttgattagtgtactagatccattttaatttggaaagtg aagtgctacttatttgaacttcttaaaaatgctaattttaacatctaaagagttaactaagaaaagcttagtaacatgat gtaccaagttgaatatgctgttatccttatttagaatagaaaattggtatttctacgttttatccattctaaggcaggtt aaaaaattgtatttccatgactacctatatatttcttgaatttattattgtaaagttgattcatagtcaaacaattaaat gtttaaattaagattaagacactagagaatgatttatttgctgtcctttaattgcagcaaatccttgctgttcccaccca tgtcaaaaccgaggtgtatgtatgagtgtgggatttgaccagtataagtgcgattgtacccggacaggattctatggaga aaactgctcaacacgtaagtttgtcctttggttgcctcattaggagtggggctggatacagttatcattgtatagatttg tgtcttataatgagtcccattaatttctccctccctttcttcgtcttcttgcagcggaatttttgacaagaataaaatta tttctgaaacccactccaaacacagtgcactacatacttacccacttcaagggattttggaacgttgtgaataacattcc cttccttcgaaatgcaattatgagttatgtcttgacatgtaagtacaagtgtctttctaaggtttttagccttctcaaag aaaaatatgctttataatactgtaagcctaatctaaaaacatatttccaagcttatcaaaaagactttaagatagctttt aagtttgccttccatcttaatcgccaaaaatattgacatttagtcccatccagtttatacagtctgctcacaactctgta tacctcttctaacctttactgtttggtcagtttgtggaggtagcatggtccagctgtttattgaatgcccatgggccaca gaattgttctgaacatgtagcacccattaaaataaatttggatttggatcagcaagaaaataactttccatgattctaaa gtgggtgccatactcagccattcctttcataggcctcttggatagtgagcagatggctacctgaaaaatcaatattgcca gattataatgtgcagagtatatgtattttattaaagatgtatttcaagtggccattagactataaagtgtagttgtttaa aaatagattttttttattttggagttacattcaacctcaggtgccactttccacattttacaataaaaataatggttgat ttacttaacaaatgagaataaataaaacatttttttctttgaaaatttcagccagatcacatttgattgacagtccacca acttacaatgctgactatggctacaaaagctgggaagccttctctaacctctcctattatactagagcccttcctcctgt gcctgatgattgcccgactcccttgggtgtcaaaggtgagtaagaagaatccattagagatgtattaactataagacggg ctgcattgctgccaaaaaaaaaaattgaccttagactaccatttatttattaacaaaagcag^'tttttacttttagcatgg ttatctatgggtattttttaaagtatgagtctatataaactattatgtaaaagcaaatgagcgtcttggtataatgtctt aatattttcaaattatttctttagaaatgaaataattctaattaaaatagataaaatcattcagtaagaagttgttccac catatcttagaactgttgtttatattatgatcctattcacaattgtaattctcatataaatgaagaattcttggtagatt gacagtcaccatctcctttcttgaatacatagatggattcttaccttagctttctcatttttcaggtaaaaagcagcttc ctgattcaaatgagattgtggaaaaattgcttctaagaagaaagttcatccctgatccccagggctcaaacatgatgttt gcattctttgcccagcacttcacgcatcagtttttcaagacagatcataagcgagggccagctttcaccaacgggctggg ccatggggtaagatagagttaatatcttagagttagtaaaattataccaaatcatagtcaagggctaacattaaaggaga tatacagatagatagatccaaataacttatccactttttttaaaaagaagtcttatctataaaaaccttaaaggaatttt ccatttacttcactggtctagtaaaattatacacacacacagacatgcacacacatatataaacattcacacacatacat atgtacaggtattgttatttgtaatttgacccttgtattttttagtttaaaatgttagtactgcaaaatgttatgtcctc aaaaacacattgtaccatgattatgccgctttcaatattgtaaagtgaggtttttgccgcattattattttttggatttc aatagcatagcttcaagttattσgtaagaattttttataaataatacatttttatacttttttataattaccatatcatc atagtgaagtatataatatatatgatataagctcaatatagtatattaattccgttaaacacaaagacatatcagtttgt agctttggtggataaacaaattaatttagcaattcatggctatgaaaaatgtatattttatttaaaaattttaaagaaag ctaaatgatcaaattatttaatgatgaattatatgatagacactttatataagaaaaacttcaacagcaacaaattaaaa ttttttcatcattttctaggtggacttaaatcatatttacggtgaaactctggctagacagcgtaaactgcgccttttca aggatggaaaaatgaaatatcaggtatgcttcctttgactattaagacttagttattaccgcttatacccatattttaaa atccctaaaaatgtgttccttaactttttaactgatgtttatttatttatttatttttttagataattgatggagagatg tatcctcccacagtcaaagatactcaggcagagatgatctaccctcctcaagtccctgagcatctacggtttgctgtggg gcaggaggtctttggtctggtgcctggtctgatgatgtatgccacaatctggctgcgggaacacaacagagtatgcgatg tgcttaaacaggagcatcctgaatggggtgatgagcagttgttccagacaagcaggctaatactgataggtaaacaagaa aatgatttatataaaaccctcttccccagggaaaattagtgtgctatctttgttatgttttgagtaaatgacaagatgtg gtaaatgaaaactcacacattctatatacattaaatatgtaagcatgactgataaaatagctatcttttgatactgacaa ggaagaaaacagaaatgaaggaatagcaaattttaaaaattgcattccagttgcttgaaagcttgtgatcagatgcaata aatgtttttattatttattttgtgcaaataggagagactattaagattgtgattgaagattatgtgcaacacttgagtgg ctatcacttcaaactgaaatttgacccagaactacttttcaacaaacaattccagtaccaaaatcgtattgctgctgaat ttaacaccctctatcactggcatccccttctgcctgacacctttcaaattcatgaccagaaatacaactatcaacagttt atctacaacaactctatattgctggaacatggaattacccagtttgttgaatcattcaccaggcaaattgctggcagggt aagcattattattgaaaaccaaaacaaaagactagtcagtaactttagaatttctgccacggaaattatttttcttaaac ttactaaaagagtagttagttatattgctagtaaaattattttattgatataagaagcctaactttgtttgaaaagtcta aacttttagtctagtctacagttgtcagacaaatagcaaattgtacccctaccttaaaaatattttcaaaaagtatctat aatcttataggaataaatattttaggcttgaatactagtgttatttttgaaatgtaaaaaggcaaattagttctaggctg gtgtcccattgaattttaagcagagctcctgttgaaatgtaggtaagcatctttccagcaaataaaaattgtctccgctg ggagtttcagttttacctgatttgtacctaaggcaagctgaatacaaacagtaaatatgcctaaaattcttgttttacaa ctaattttactttccacaggttgctggtggtaggaatgttccacccgcagtacagaaagtatcacaggcttccattgacc agagcaggcagatgaaataccagtcttttaatgagtaccgcaaacgctttatgctgaagccctatgaatcatttgaagaa cttacaggtaagaaacagtttctaaacttcttcgttttttgtttgtttgtttgtttttgttgtttttggttttcttttcg agatggagccgccctctgtcacccaggctggagtgcagtggcgccatctcggctcactgcaacctccgcctcctgggttc aagcaattctcctgcctcaacttcctgagtagctgggactacaggctcacgtcgcacgcatggataattttttgtatttt cagtatagacggggtttcaccgtgttagccaggctggtctcaaactcctgacctagtgatccgccggcttcggcctcccg aagtgctgggattacaggcgtgagccaccgcgcctggcccctaaacttcttaaaagaatcaggggtcaaatggaaacaga gaagttggcagcaaattgagcaaaagaatcaaactgttttttattttgtgaagtttgacattggttgtatctctgtcttc atcgccttcacaggagaaaaggaaatgtctgcagagttggaagcactctatggtgacatcgatgctgtggagctgtatcc tgcccttctggtagaaaagcctcggccagatgccatctttggtgaaaccatggtagaagttggagcaccattctccttga aaggacttatgggtaatgttatatgttctcctgcctactggaagccaagcacttttggtggagaagtgggttttcaaatc a caacactgcctcaattcagtctctcatctgcaataacgtgaagggctgtccctttacttcattcagtgttccagatcc agagctcattaaaacagtcaccatcaatgcaagttcttcccgctccggactagatgatatcaatcccacagtactactaa aagaacgttcgactgaactgtagaagtctaatgatcatatttatttatttatatgaaccatgtctattaatttaattatt taataatatttatattaaactccttatgttacttaacatcttctgtaacagaagtcagtactcctgttgcggagaaagga gtcatacttgtgaagacttttatgtcactactctaaagattttgctgttgctgttaagtttggaaaacagtttttattct gttttataaaccagagagaaatgagttttgacgtctttttacttgaatttcaacttatattataagaacgaaagtaaaga tgtttgaatacttaaacactatcacaagatggcaaaatgctgaaagtttttacactgtcgatgtttccaatgcatcttcc atgatgcattagaagtaactaatgtttgaaattttaaagtacttttggttatttttctgtcatcaaacaaaaacaggtat cagtgcattattaaatgaatatttaaattagacattaccagtaatttcatgtctactttttaaaatcagcaatgaaacaa taatttgaaatttctaaattcatagggtagaatcacctgtaaaagcttgtttgatttcttaaagttattaaacttgtaca tataccaaaaagaagctgtcttggatttaaatctgtaaaatcagatgaaattttactacaattgcttgttaaaatatttt ataagtgatgttcctttttcaccaagagtataaacctttttagtgtgactgttaaaacttccttttaaatcaaaatgcca aatttattaaggtggtggagccactgcagtgttatctcaaaataagaatattttgttgagatattccagaatttgtttat atggctggtaacatgtaaaatctatatcagcaaaagggtctacctttaaaataagcaataacaaagaagaaaaccaaatt attgttcaaatttaggtttaaacttttgaagcaaacttttttttatccttgtgcactgcaggcctggtactcagattttg ctatgaggttaatgaagtaccaagctgtgcttgaataacgatatgttttctcagattttctgttgtacagtttaatttag cagtccatatcacattgcaaaagtagcaatgacctcataaaatacctcttcaaaatgcttaaattcatttcacacattaa ttttatctcagtcttgaagccaattcagtaggtgcattggaatcaagcctggctacctgcatgctgttccttttcttttc ttcttttagccattttgctaagagacacagtcttctcatcacttcgtttctcctattttgttttactagttttaagatca gagttcactttctttggactctgcctatattttcttacctgaacttttgcaagttttcaggtaaacctcagctcaggact gctatttagctcctcttaagaagattaaaagagaaaaaaaaaggcccttttaaaaatagtatacacttattttaagtgaa aagcagagaattttatttatagctaattttagctatctgtaaccaagatggatgcaaagaggctagtgcctcagagagaa ctgtacggggtttgtgactggaaaaagttacgttcccattctaattaatgccctttcttatttaaaaacaaaaccaaatg atatctaagtagttctcagcaataataataatgacgataatacttcttttccacatctcattgtcactgacatttaatgg tactgtatattacttaatttattgaagattattatttatgtcttattaggacactatggttataaactgtgtttaagcct acaatcattgatttttttttgttatgtcacaatcagtatattttctttggggttacctctctgaatattatgtaaacaat ccaaagaaatgattgtattaagatttgtgaataaatttttagaaatctgattggcatattgagatatttaaggttgaatg tttgtccttaggataggcctatgtgctagcccacaaagaatattgtctcattagcctgaatgtgccataagactgacctt ttaaaatgttttgagggatctgtggatgcttcgttaatttgttcagccacaatttattgagaaaatattctgtgtcaagc actgtgggttttaatatttttaaatcaaacgctgattacagataatagtatttatataaataattgaaaaaaattttctt ttgggaagagggagaaaatgaaataaatatcattaaagataactcaggagaatcttctttacaattttacgtttagaatg tttaaggttaagaaagaaatagtcaatatgcttgtataaaacactgttcactgttttttttaaaaaaaaaacttgatttg ttattaacattgatctgctgacaaaacctgggaatttgggttgtgtatgcgaatgtttcagtgcctcagacaaatgtgta tttaacttatgtaaaagataagtctggaaataaatgtctgtttatttttgtactatttaaaaaaaaaaaaaaaaatcgat gtcgactcgagtc (SEQ ID NO:12052) ctcgatcaaaccttttttttatggtacacaatagtcacagtacttttccatataaaacaggtttagtggtcttaatttag tttggcacatttaatacactcccatgaccagcatcccaaatgtacctatccgttttattttattgtctcagaattgtcag ttatttaataaattatgtaacttttttccttatgctcagatttgcacttctttctaaaactctgcccatccttaaagtcc cagattctccttgaacttttttttttgactttccaagtacatggaactcttcactctatcctgctatataaggtgacaga atttccactatgggatagatggagttcaattcctttgagtttaaaataatctaaatataattattccttatgccctgttt ttccctcacttttgtatccaaatctcttttcagacaacagaacaattaatgtctgataaggaagacaatgatgatgatca cttcaaaatgaattcaggattgtaatgtaaaattttagtactctctcacagtatggattctaacatggcttctaacccaa actaacattagtagctctaactataaacttcaaatttcagtagatgcaacctactcctttaaaatgaaacagaagattga aattattaaattatcaaaaagaaaatgatccacgctcttagttgaaatttcatgtaagattccatgcaataaataggagt gccataaatggaatgatgaaatatgactagaggaggagaaaggctcctagatgagatgggattttaggcatccgtgtctc atgaggaatcagttgtgtcactaggcaaaacagtaaaaaaaaaaacctccaagtgagtctcttatttatttttttcttat aagacttctacaaattgaggtacctggtgtagttttatttcaggttttatgctgtcattttcctgtaatgctaaggactt aggacataactgaattttctattttccacttcttttctggtgtgtgtgtatatatatatgtatatatacacacacacata tacatatatatattttttagtatctcaccctcacatgctcctccctgagcactacccatgatagatgttaaacaaaagca aagatgaaattccaactgtcaaaatcccccctccatctaattaatccctcacccaactatgttccaaaacgagaatagaa aattagccccaataagcccaggcaactgaaaagtaaatgctatgttgtactttgatccatggtcacaactcataatcttg gaaaagtggacagaaaagacaaaagagtgaactttaaaactcgaatttattttaccagtatctcctatgaagggctagta accaaaataatccacgcatcagggagagaaatgccttaaggcatacgttttggacatttagcgtccctgcaaattctggc catcgccgcttcctttgtccatcagaaggcaggaaactttatattggtgacccgtggagctcacattaactatttacagg gtaactgcttaggaccagtattatgaggagaatttacctttcccgcctctctttccaagaaacaaggagggggtgaaggt acggagaacagtatttcttctgttgaaagcaacttagctacaaagataaattacagctatgtacactgaaggtagctatt tcattccacaaaataagagttttttaaaaagctatgtatgtatgtgctgcatatagagcagatatacagcctattaagcg tcgtcactaaaacataaaacatgtcagcctttcttaaccttactcgccccagtctgtcccgacgtgacttcctcgaccct ctaaagacgtacagaccagacacggcggcggcggcgggagaggggattccctgcggccccggacctcagggccgctcaga ttcctggagaggaagccaagtgtccttctgccctcccccggtatcccatccaaggcgatcagtccacaactggctctcgg aagcactcgggcaaagactgcgaagaagaaaagacatctggcggaaacctgtgcgcctggggcggtggaactcggggagg agagggagggatcagacaggagagtggggactaccccctctgctcccaaattggggcagcttcctgggtttccgattttc tcatttccgtgggtaaaaaaccctgcccccaccggcttacgcaatttttttaaggggagaggagggaaaaatttgtgggg ggtacgaaaaggcggaaagaaacagtcatttcgtcacatgggcttggttttcagtcttataaaaaggaaggttctctcgg ttagcgaccaattgtcatacgacttgcagtgagcgtcaggagcacgtccaggaactcctcagcagcgcctccttcagctc gtccaggaactcctcagcagcgcctccttcagctccacagccagacgccctcagacagcaaagcctacccccgcgccgcg ccctgcccgccgctgcgatgctcgcccgcgccctgctgctgtgcgcggtcctggcgctcagccatacagcaaatccttgc tgttcccacccatgtcaaaaccgaggtgtatgtatgagtgtgggatttgaccagtataagtgcgattgtacccggacagg attctatggagaaaactgctcaacaccggaatttttgacaagaataaaattatttctgaaacccactccaaacacagtgc actacatacttacccacttcaagggattttggaacgttgtgaataacattcccttccttcgaaatgcaattatgagttat gtgttgacatccagatcacatttgattgacagtccaccaacttacaatgctgactatggctacaaaagctgggaagcctt ctctaacctctcctattatactagagcccttcctcctgtgcctgatgattgcccgactcccttgggtgtcaaaggtaaaa agcagcttcctgattcaaatgagattgtgggaaaattgcttctaagaagaaagttcatccctgatccccagggctcaaac atgatgtttgcattctttgcccagcacttcacgcatcagtttttcaagacagatcataagcgagggccagctttcaccaa cgggctgggccatggggtggacttaaatcatatttacggtgaaactctggctagacagcgtaaactgcgccttttcaagg atggaaaaatgaaatatcagataattgatggagagatgtatcctcccacagtcaaagatactcaggcagagatgatctac cctcctcaagtccctgagcatctacggtttgctgtggggcaggaggtctttggtctggtgcctggtctgatgatgtatgc cacaatctggctgagggaacacaacagagtatgcgatgtgcttaaacaggagcatcctgaatggggtgatgagcagttgt tccagacaagcaggctaatactgataggagagactattaagattgtgattgaagattatgtgcaacacttgagtggctat cacttcaaactgaaatttgacccagaactacttttcaacaaacaattccagtaccaaaatcgtattgctgctgaatttaa caccctctatcactggcatccccttctgcctgacacctttcaaattcatgaccagaaatacaactatcaacagtttatct acaacaactctatattgctggaacatggaattacccagtttgttgaatcattcaccaggcaaattgctggcagggttgct ggtggtaggaatgttccacccgcagtacagaaagtatcacaggcttccattgaccagagcaggcagatgaaataccagtc ttttaatgagtaccgcaaacgctttatgctgaagccctatgaatcatttgaagaacttacaggagaaaaggaaatgtctg cagagttggaagcactctatggtgacatcgatgctgtggagctgtatcctgcccttctggtagaaaagcctcggccagat gccatctttggtgaaaccatggtagaagttggagcaccattctccttgaaaggacttatgggtaatgttatatgttctcc tgcctactggaagccaagcacttttggtggagaagtgggttttcaaatcatcaacactgcctcaattcagtctctcatct gcaataacgtgaagggctgtccctttacttcattcagtgttccagatccagagctcattaaaacagtcaccatcaatgca agttcttcccgctccggactagatgatatcaatcccacagtactactaaaagaacgttcgactgaactgtagaagtctaa tgatcatatttatttatttatatgaaccatgtctattaatttaattatttaataatatttatattaaactccttatgtta cttaacatcttctgtaacagaagtcagtactcctgttgcggagaaaggagtcatacttgtgaagacttttatgtcactac tctaaagattttgctgttgctgttaagtttggaaaacagtttttattctgttttataaaccagagagaaatgagttttga cgtctttttacttgaatttcaacttatattataaggacgaaagtaaagatgtttgaatacttaaacactatcacaagatg ccaaaatgctgaaagtttttacactgtcgatgtttccaatgcatcttccatgatgcattagaagtaactaatgtttgaaa ttttaaagtacttttgggtatttttctgtcatcaaacaaaacaggtatcagtgcattattaaatgaatatttaaattaga cattaccagtaatttcatgtctactttttaaaatcagcaatgaaacaataatttgaaatttctaaattcatagggtagaa tcacctgtaaaagcttgtttgatttcttaaagttattaaacttgtacatataccaaaaagaagctgtcttggatttaaat ctgtaaaatcagatgaaattttactacaattgcttgttaaaatattttataagtgatgttcctttttcaccaagagtata aacctttttagtgtgactgttaaaacttccttttaaatcaaaatgccaaatttattaaggtggtggagccactgcagtgt tatctcaaaataagaatatcctgttgagatattccagaatctgtttatatggctggtaacatgtaaaaaccccataaccc cgccaaaaggggtcctacccttgaacataaagcaataaccaaaggagaaaagcccaaattattggttccaaatttagggt ttaaactttttgaagcaaacttttttttagccttgtgcactgcagacctggtactcagattttgctatgaggttaatgaa gtaccaagctgtgcttgaataacgatatgttttctcagattttctgttgtacagtttaatttagcagtccatatcacatt gcaaaagtagcaatgacctcataaaatacctcttcaaaatgcttaaattcatttcacacattaattttatctcagtcttg aagccaattcagtaggtgcattggaatcaagcctggctacctgcatgctgttccttttcttttcttcttttagccatttt gctaagagacacagtcttctcaaacacttcgtttctcctattttgttttactagttttaagatcagagttcactttcttt ggactctgcctatattttcttacctgaacttttgcaagttttcaggtaaacctcagctcaggactgctatttagctcctc ttaagaagattaaaaaaaaaaaaaaaggagctcacattaactatttacagggtaactgcttaggaccagtattatgagga gaatttacctttcccgcctctctttccaagaaacaaggagggggtgaaggtacggagaacagtatttcttctgttgaaag caacttagctacaaagataaattacagctatgtacactgaaggtagctatttcattccacaaaataagagttttttaaaa agctatgtatgtatgtgctgcatatagagcagatatacagcctattaagcgtcgtcactaaaacataaaacatgtcagcc tttcttaaccttactcgccccagtctgtcccgacgtgacttcctcgaccctctaaagacgtacagaccagacacggcggc ggcggcgggagaggggattccctgcgcccccggacctcagggccgctcagattcctggagaggaagccaagtgtccttct gccctcccccggtatcccatccaaggcgatcagtccagaactggctctcggaagcgctcgggcaaagactgcgaagaaga aaagacatctggcggaaacctgtgcgcctggggcggtggaactcggggaggagagggagggatcagacaggagagtgggg actaccccctctgctcccaaattggggcagcttcctgggtttccgattttctcatttccgtgggtaaaaaaccctgcccc caccgggcttacgcaatttttttaaggggagaggagggaaaaaatttgtgggggggtacgaaaaggcggaaagaaacagt cattcacatgggcttggttttcagtcttataaaaaggaaggttctctcggttagcgaccaattgtcatacgacttgcagt gagcgtcaggagcacgtccaggaactcctcagcagcgcctccttcagctccacagccagacgccctcagacagcaaagcc tacccccgcgccgcgccctgcccgccgctcggatgctcgcccgcgccctgctgctgtgcgcggtcctggcgctcagccat acaggtgagtacctggcgccgcgcaccggggactccggttccacgcacccgggcagagtttccgctctgacctcctgggt ctatcccag actccgacttctctccgaatagagaagctacgtgacttgggaaagagcttggaccgctagagtccgaaag aactccgtggatattccagctttcccacaagcactga cattatgagccagttacttaaccgatctgagacactctcacc tcctaaatagggatagatgatactaatttgcaggttgtcattatgataagacaggatctgatcaatatatgtgaattgtt tatatttggaacctttttattgagtggaagaagttgttttaaatattctagtcagttctttcctgctcccaggaaagccc ggattatgttttaagataagcaaaatgtcttaaaagtaagctgttttactttgaatttttccctaaatgttgattagtgt actagatccattttaatttggaaagtgaagtgctacttatttgaacttcttaaaaatgctaattttaacatctaaagagt taactaagaaaagcttagtaacatgatgtaccaagttgaatatgctgttatccttatttagaatagaaaattggtatttc tacgttttatccattctaaggcaggttaaaaaattgtatttccatgactacctatatatttcttgaatttattattgtaa agttgattcatagtcaaacaattaaatgtttaaattaagattaagacactagagaatgatttatttgctgtcctttaatt gcagcaaatccttgctgttcccacccatgtcaaaaccgaggtgtatgtatgagtgtgggatttgaccagtataagtgcga ttgtacccggacaggattctatggagaaaactgctcaacacgtaagtttgtcctttggttgcctcattaggagtggggct ggatacagttatcattgtatagatttgtgtcttataatgagtcccattaatttctccctccctttcttcgtcttcttgca gcggaatttttgacaagaataaaattatttctgaaacccactccaaacacagtgcactacatacttacccacttcaaggg attttggaacgttgtgaataacattcccttccttcgaaatgcaattatgagttatgtcttgacatgtaagtacaagtgtc tttctaaggtttttagccttctcaaagaaaaatatgctttataatactgtaagcctaatctaaaaacatatttccaagct tatcaaaaagactttaagatagcttttaagtttgccttccatcttaatcgccaaaaatattgacatttagtcccatccag tttatacagtctgctcacaactctgtatacctcttctaacctttactgtttggtcagtttgtggaggtagcatggtccag ctgtttattgaatgcccatgggccacagaattgttctgaacatgtagcacccattaaaataaatttggatttggatcagc aagaaaataactttccatgattctaaagtgggtgccatactcagccattcctttcataggcctcttggatagtgagcaga tggctacctgaaaaatcaatattgccagattataatgtgcagagtatatgtattttattaaagatgtatttcaagtggcc attagactataaagtgtagttgtttaaaaatagattttttttattttggagttacattcaacctcaggtgccactttcca cattttacaataaaaataatggttgatttacttaacaaatgagaataaataaaacatttttttctttgaaaatttcagcc agatcacatttgattgacagtccaccaacttacaatgctgactatggctacaaaagctgggaagccttctctaacctctc ctattatactagagcccttcctcctgtgcctgatgattgcccgactcccttgggtgtcaaaggtgagtaagaagaatcca ttagagatgtattaactataagacgggctgcattgctgccaaaaaaaaaaattgaccttagactaccatttatttattaa caaaagcagtttttacttttagcatggttatctatgggtattttttaaagtatgagtctatataaactattatgtaaaag caaatgagcgtcttggtataatgtcttaatattttcaaattatttctttagaaatgaaataattctaattaaaatagata aaatcattcagtaagaagttgttccaccatatcttagaactgttgtttatattatgatcctattcacaattgtaattctc atataaatgaagaattcttggtagattgacagtcaccatctcctttcttgaatacatagatggattcttaccttagcttt ctcatttttcaggtaaaaagcagcttcctgattcaaatgagattgtggaaaaattgcttctaagaagaaagttcatccct gatccccagggctcaaacatgatgtttgcattctttgcccagcacttcacgcatcagtttttcaagacagatcataagcg agggccagctttcaccaacgggctgggccatggggtaagatagagttaatatcttagagttagtaaaattataccaaatc atagtcaagggctaacattaaaggagatatacagatagatagatccaaataacttatccactttttttaaaaagaagtct tatctataaaaaccttaaaggaattttccatttacttcactggtctagtaaaattatacacacacacagacatgcacaca catatataaacattcacacacatacatatgtacaggtattgttatttgtaatttgacccttgtattttttagtttaaaat gttagtactgcaaaatgttatgtcctcaaaaacacattgtaccatgattatgccgctttcaatattgtaaagtgaggttt ttgccgcattattattttttggatttcaatagcatagcttcaagttattcgtaagaattttttataaataatacattttt atacttttttataattaccatatcatcatagtgaagtatataatatatatgatataagctcaatatagtatattaattcc gttaaacacaaagacatatcagtttgtagctttggtggataaacaaattaatttagcaattcatggctatgaaaaatgta tattttatttaaaaattttaaagaaagctaaatgatcaaattatttaatgatgaattatatgatagacactttatataag aaaaacttcaacagcaacaaattaaaattttttcatcattttctaggtggacttaaatcatatttacggtgaaactctgg ctagacagcgtaaactgcgccttttcaaggatggaaaaatgaaatatcaggtatgcttcctttgactattaagacttagt tattaccgcttatacccatattttaaaatccctaaaaatgtgttccttaactttttaactgatgtttatttatttattta tttttttagataattgatggagagatgtatcctcccacagtcaaagatactcaggcagagatgatctaccctcctcaagt ccctgagcatctacggtttgctgtggggcaggaggtctttggtctggtgcctggtctgatgatgtatgccacaatctggc tgcgggaacacaacagagtatgcgatgtgcttaaacaggagcatcctgaatggggtgatgagcagttgttccagacaagc aggctaatactgataggtaaacaagaaaatgattta ataaaaccctcttccccagggaaaattagtgtgctatctttgt tatgttttgagtaaatgacaagatgtggtaaatgaaaactcacacattctatatacattaaatatgtaagcatgactgat aaaatagctatcttttgatactgacaaggaagaaaacagaaatgaaggaatagcaaattttaaaaattgcattccagttg cttgaaagcttgtgatcagatgcaataaatgtttttattatttattttgtgcaaataggagagactattaagattgtgat tgaagattatgtgcaacacttgagtggctatcacttcaaactgaaatttgacccagaactacttttcaacaaacaattcc agtaccaaaatcgtattgctgctgaatttaacaccctctatcactggcatccccttctgcctgacacctttcaaattcat gaccagaaatacaactatcaacagtttatctacaacaactctatattgctggaacatggaattacccagtttgttgaatc attcaccaggcaaattgctggcagggtaagcattattattgaaaaccaaaacaaaagactagtcagtaactttagaattt ctgccacggaaattatttttcttaaacttactaaaagagtagttagttatattgctagtaaaattattttattgatataa gaagcctaactttgtttgaaaagtctaaacttttagtctagtctacagttgtcagacaaatagcaaattgtacccctacc ttaaaaatattttcaaaaagtatctataatcttataggaataaatattttaggcttgaatactagtgttatttttgaaat gtaaaaaggcaaattagttctaggctggtgtcccattgaattttaagcagagctcctgttgaaatgtaggtaagcatctt tccagcaaataaaaattgtctccgctgggagtttcagttttacctgatttgtacctaaggcaagctgaatacaaacagta aatatgcctaaaattcttgttttacaactaattttactttccacaggttgctggtggtaggaatgttccacccgcagtac agaaagtatcacaggcttccattgaccagagcaggcagatgaaataccagtcttttaatgagtaccgcaaacgctttatg ctgaagccctatgaatcatttgaagaacttacaggtaagaaacagtttctaaacttcttcgttttttgtttgtttgtttg tttttgttgtttttggttttcttttcgagatggagccgccctctgtcacccaggctggagtgcagtggcgccatctcggc tcactgcaacctccgcctcctgggttcaagcaattctcctgcctcaacttcctgagtagctgggactacaggctcacgtc gcacgcatggataattttttgtattttcagtatagacggggtttcaccgtgttagccaggctggtctcaaactcctgacc tagtgatccgccggcttcggcctcccgaagtgctgggattacaggcgtgagccaccgcgcctggcccctaaacttcttaa aagaatcaggggtcaaatggaaacagagaagttggcagcaaattgagcaaaagaatcaaactgttttttattttgtgaag tttgacattggttgtatctctgtcttcatcgccttcacaggagaaaaggaaatgtctgcagagttggaagcactctatgg tgacatcgatgctgtggagctgtatcctgcccttctggtagaaaagcctcggccagatgccatctttggtgaaaccatgg tagaagttggagcaccattctccttgaaaggacttatgggtaatgttatatgttctcctgcctactggaagccaagcact tttggtggagaagtgggttttcaaatcatcaacactgcctcaattcagtctctcatctgcaataacgtgaagggctgtcc ctttacttcattcagtgttccagatccagagctcattaaaacagtcaccatcaatgcaagttcttcccgctccggactag atgatatcaatcccacagtactactaaaagaacgttcgactgaactgtagaagtctaatgatcatatttatttatttata tgaaccatgtctattaatttaattatttaataatatttatattaaactccttatgttacttaacatcttctgtaacagaa gtcagtactcctgttgcggagaaaggagtcatacttgtgaagacttttatgtcactactctaaagattttgctgttgctg ttaagtttggaaaacagtttttattctgttttataaaccagagagaaatgagttttgacgtctttttacttgaatttcaa cttatattataagaacgaaagtaaagatgtttgaatacttaaacactatcacaagatggcaaaatgctgaaagtttttac actgtcgatgtttccaatgcatcttccatgatgcattagaagtaactaatgtttgaaattttaaagtacttttggttatt tttctgtcatcaaacaaaaacaggtatcagtgcattattaaatgaatatttaaattagacattaccagtaatttcatgtc tactttttaaaatcagcaatgaaacaataatttgaaatttctaaattcatagggtagaatcacctgtaaaagcttgtttg atttcttaaagttattaaacttgtacatataccaaaaagaagctgtcttggatttaaatctgtaaaatcagatgaaattt tactacaattgcttgttaaaatattttataagtgatgttcctttttcaccaagagtataaacctttttagtgtgactgtt aaaacttccttttaaatcaaaatgccaaatttattaaggtggtggagccactgcagtgttatctcaaaataagaatattt tgttgagatattccagaatttgtttatatggctggtaacatgtaaaatctatatcagcaaaagggtctacctttaaaata agcaa^'taacaaagaagaaaaccaaattattgttcaaatttaggtttaaacttttgaagcaaacttttttttatccttgtg cactgcaggcctggtactcagattttgctatgaggttaatgaagtaccaagctgtgcttgaataacgatatgttttctca gattttctgttgtacagtttaatttagcagtccatatcacattgcaaaagtagcaatgacctcataaaatacctcttcaa aatgcttaaattcatttcacacattaattttatctcagtcttgaagccaattcagtaggtgcattggaatcaagcctggc tacctgcatgctgttccttttcttttcttcttttagccattttgctaagagacacagtcttctcatcacttcgtttctcc tattttgttttactagttttaagatcagagttcactttctttggactctgcctatattttcttacctgaacttttgcaag ttttcaggtaaacctcagctcaggactgctatttagctcctcttaagaagattaaaagagaaaaaaaaaggcccttttaa aaatagtatacacttattttaagtgaaaagcagagaattttatttatagctaattttagctatctgtaaccaagatggat gcaaagaggctagtgcctcagagagaactgtacggggtttgtgactggaaaaagttacgttcccattctaattaatgccc tttcttatttaaaaacaaaaccaaatgatatctaagtagttctcagcaataataataatgacgataatacttcttttcca catctcattgtcactgacatttaatggtactgtatattacttaatttattgaagattattatttatgtcttattaggaca ctatggttataaactgtgtttaagcctacaatcattgatttttttttgttatgtcacaatcagtatattttctttggggt tacctctctgaatattatgtaaacaatccaaagaaatgattgtattaagatttgtgaataaatttttagaaatctgattg gcatattgagatatttaaggttgaatgtttgtccttaggataggcctatgtgctagcccacaaagaatattgtctcatta gcctgaatgtgccataagactgaccttttaaaatgttttgagggatctgtggatgcttcgttaatttgttcagccacaat ttattgagaaaatattctgtgtcaagcactgtgggttttaatatttttaaatcaaacgctgattacagataatagtattt atataaataattgaaaaaaattttcttttgggaagagggagaaaatgaaataaatatcattaaagataactcaggagaat cttctttacaattttacgtttagaatgtttaaggttaagaaagaaatagtcaatatgcttgtataaaacactgttcactg ttttttttaaaaaaaaaacttgatttgttattaacattgatctgctgacaaaacctgggaatttgggttgtgtatgcgaa tgtttcagtgcctcagacaaatgtgtatttaacttatgtaaaagataagtctggaaataaatgtctgtttatttttgtac tatttaaaaaaaaaaaaaaaaatcgatgtcgactcgagtc (SEQ ID NO: 12053) gaattccggagttccgggcgcgcgcgacgtcagtttgagttctgtgttctccccgcccgtgtcccgcccgacccgcgccc gcgatgctggcgctgcgctgcggctcccgctggctcggcctgctctccgtcccgcgctccgtgccgctgcgcctccccgc ggcccgcgcctgcagcaagggctccggcgacccgtcctcttcctcctcctccgggaacccgctcgtgtacctggacgtgg acgccaacgggaagccgctcggccgcgtggtgctggagctgaaggcagatgtcgtcccaaagacagctgagaacttcaga gccctgtgcactggtgagaagggcttcggctacaaaggctccaccttccacagggtgatcccttccttcatgtgccaggc gggcgacttcaccaaccacaatggcacaggcgggaagtccatctacggaagccgctttcctgacgagaactttacactga agcacgtggggccaggtgtcctgtccatggctaatgctggtcctaacaccaacggctcccagttcttcatctgcaccata aagacagactggttggatggcaagcatgttgtgttcggtcacgtcaaagagggcatggacgtcgtgaagaaaatagaatc tttcggctctaagagtgggaggacatccaagaagattgtcatcacagactgtggccagttgagctaatctgtggccaggg tgctggcatggtggcagctgcaaatgtccatgcacccaggtggccgcgttgggctgtcagccaaggtgcctgaaacgata cgtgtgcccactccactgtcacagtgtgcctgaggaaggctgctagggatgttagacggaattcc (SEQ ID NO: 12054) ttttgcagacgccaccgccgaggaaaaccgtgtactattagccatggtc (SEQ ID NO: 12055) cgggaacgcaacatgaaggtgctccttgccgccgccctcatcgcggggtccgtcttcttcctgctgctgccgggaccttc tgcggccgatgagaagaagaaggggcccaaagtcaccgtcaaggtgtattttgacctacgaattggagatgaagatgtag gccgggtgatctttggtctcttcggaaagactgttccaaaaacagtggataattttgtggccttagctacaggagagaaa ggatttggctacaaaaacagcaaattccatcgtgtaatcaaggacttcatgatccagggcggagacttcaccaggggaga tggcacaggaggaaagagcatctacggtgagcgcttccccgatgagaacttcaaactgaagcactacgggcctggctggg tcagcatggccaacgcaggcaaagacaccaacggctcccagtte eatcacgacagtcaagacagcctggctagatggc aagcatgtggtgtttggcaaagttctagagggcatggaggtggtgcggaaggtggagagcaccaagacagacagccggga taaacccctgaaggatgtgatcatcgcagactgcggcaagatcgaggtggagaagccctttgccatcgccaaggagtagg gcacagggacatctttctttgagtgaccgtctgtgcaggccctgtagtccgccacagggctctgagctgcactggccccg gtgctggcatctggtggagcggacccactcccctcacattccacaggcccatggactcacttttgtaacaaactcctacc aacactgaccaataaaaaaaaatgtgggttttttttttttttaataaaaaa (SEQ ID NO: 12056) gaaggtgctccttgccgccgccctcatcgcggggtccgtcttcttcctgctgctgccgggaccttctgcggccgatgaga agaagaaggggcccaaagtcaccgtcaaggtgtattttgacctacgaattggagatgaagatgtaggccgggtgatcttt ggtctctttggaaagactgttccaaaaacagtggataattttgtggccttagctacaggagagaaaggatttggctacaa aaacagcaaattccatcgtgtaatcaaggacttcatgatccagggcggagacttcaccaggggagatggcacaggaggaa agagcatctacggtgagcgcttccccgatgagaacttcaaactgaagcactacgggcctggctgggtgagcatggccaac gcaggcaaagacaccaacggctcccagttcttcatcacgacagtcaagacagcctggctagatggcaagcatgtggtgtt tggcaaagttctagagggcatggaggtggtgcggaaggtggagagcaccaagacagacagccgggataaacccctgaagg ^■ atgtgatca cgcagactgcggcaagatcgaggtggagaagccctttgccatcgccaaggagtagggcacagggacatct ttctttgagtgaccgtctgtgcaggccctgtagtccgccacagggctctgagctgcactggccccggtgctggcatctgg tggagcggacccactcccctcacattceacaggcccatggactcacttttgtaacaaactcctaccaacactgaccaata aaaaaaaatgtgggtttttttttttaataaaag (SEQ ID NO-.12057) gaattcccttgtaaggttttcttaaeaaaacaccagtcacataagtgcattttattttatatttttgtttatttatttga gacggagtctcttgtctctcaggctggagtgcagtggcgccatctctgctcgctgcaacctccacctcetgggttccagc gattctcctgcctcagcctcccgagggggtagctgggactacaggtgcgcaccaccatgcccagctaattttgtattttt cgtagagatggggtttcaccatgttgtccaggctggtcttgaactcctgacctcaggtgatcctcccgcctcggcctccc aaagtgctggaattacaggcgtgatccaccgcacccggcctattttttgagagagggtcacactctgtcgtcccggctgg aatgcagtgatgcgatcaccgcccactacagcctcgacctccgggctcaagcaatcctccccgcccagcctcctgagtag cgagcgcctcgacgcccagctaatttttatttttatttatttttttgtagagacggcgtctctctaagatgcccaggctg gtggccggtgtcgaactcctaagatgaagcgatcctccccggccttggcctccgcgcctcctaaagcgccaggtatgagc caccgcgcctggcctacaagtgcattttaattaaagtattattaatgtctttgcctgaagaaattcgcttttaaattgtg acttatctttcacccaaaaatcaaagcacaattcagccccgaggcgggggcggtaggagctgggcggggcgggggcaggg aaagaccaggagcagagattcaaaaagagtaagagggcaaaatgtgcataatgcatcttcacaggtaagagcctggccag gctcctgttttaatggcttcctcctgaagaagattcaagcagagtgtaagatattttcggaaagtagagcattttgaaag catttcataatctctcaaaaccggagactgctcctgtcccacctcgttagagaaaacagcgatgctcaaaggcaacctcc ttcctgacattgcctggtaggacgcgacgtggtgtttgcccgcgcggaatgcggacgcaaggctgctcctaggtctcggg gacgcgceatccccatttccgctcgcggaggcgtagggtccgggcgcgggaccccagtcgaccttgactggcggcgcgac cttgaggcctgcgttcgcctcagttgccccctctgtgcaatggggagacgcgcctcatcgcttgacaacggccgaagagc cgccgcgcttccgtctcccgcgtgcgcgcgccatgctgcccacccccgttccgcactgaccctcccccgtgccccgcgtc ccgtactgccgccccgccccgagtcccatgccgcagccaccgcgacggagcccgcaggcgggaacctgcctccgcgcgtt agcgcgcacgcgcgcctcatgtgtcgtccccatcagcgccggcttcegtctataggccagatgcactgtcactctggcga agtcgcagacccgattggccgggacggaggcgcgagaccgggttgcgggcggggccgaacgtggtataaaacgggcggga ggccaggctcgtgccgttttgcagacgccaccgccgaggaaaaccgtgtactattagccatggtcaaccccaccgtgttc ttcgacattgccgtcgacggcgagcccttgggccgcgtctcctttgaggtcgggcgggcggcggcgtgcgggaatggggc ccagaaagtgggccggggtcggggtgggtggtagcgccccaaaggcccgggcgcggggcgaccctgcttgaggggcgagc gcgggcgggctgcggcgccatttcctgacgaggggccattttgggaggtccgcgagtcgcgggaggaggccgggacgcgg cggacaaaggcaggcggggcggctgcgaggccgttgggggagggggcccgcgtccgcccgcccgcctcatgtggccgcgc cctgtcctgtccgacgcacgtgctcggcggccgcgctcaggtccgcgccttgagagtcgttgtccgccctagcttggcct gggcgccgcagaccggagccagaagcacgctcgcgggggcttgcgaccgccttcctgggaagctgtcccctggcaggcat gggtgctttacatcctgagctgggaagctgtttgcttgagggtttttctcaaggatcgaggcgcggtgtgagcccgtcca tgctcggtcctgtagatcccgggaggccatgttataaaaggagacttgctgggatgtgacgggttgccacttgaaatatc ttccatttggataaagtaggaatatttatacatgtgccccaaacgtccctccgtgtcccccacccccaagcggaaatgtg aaaatgggccttgcctttgctggtgcccaaggaccgccttccactgcagtgacggcgctggcgggggaggcgctcttgag cccctcccgattgtccctctgcctagcaagcaagttgcgactggccacaaggcaggcctcttccgaccaaggtggattac cagtgattacctaattagttttgagagcgttaaatgagttcttaaagatcagttgtaattatagcatagtatctaaactt ggcgcgtgtcttcaaagttaaatattgagtacgattccgttccagttaacatggatagaccttagggagtagcgaaatag gatgttagtggttttattcctttaaatcacatctcaaaaggccaccaatggctagtttggatcttattccgaaaatagat tgatcctcatgcagtcttcgtgaggacagagcgatttccttgttgcctaccctgtccatagtgcctggcacataggcact gaaacactgcatgttaatccacaccccaccccacctatgagtgtagtcaaagctggtaagtgacaagggctttcgtggaa acttggcctgacctaatgttgggcatcaggttacccaaagagcttcagggaaatgagaaaggacttgcaggtcttgatga gaatggaggggtaactgccaatgagggctttggctttagcgaaagtctgaaagggaagccataggaacttaaacgtaccg actataaagctctgagaaaagctgatgttttagaaagaccatacattctaggtacaaatacctaaaaactaaaaaataag tacgttggccaggcgggcggatcacgaagtcaggagattgagaccatcctgggcccctggtgaaaccccacctctattaa aaatacaaaaattagctgggcgtggtggcgcttgcctgtaatctcagctactctagaggctgaggcaggagatcgcttga accccggaggcggaggctgcagtgagccgagatcgtgccactgcactccagcctggtgacagcgagactcttgtctcaaa aaaaaaaaagtacattgctataagagaagtgcacacggatactagtagttaattcagtcacatctgtgaaatagcttata aaatgctacttttaaacaagctgtttttatgaaagggcttgtaaatgtttatggtatttaagctacctctctagccataa cgtattatacattcaagaaaggttcaaaaccagatatactagaaaccaatctttattttttaccccactactaggtaagg gcctggataccaagaagtgactgctcatctaatccataaagctatgttaacagattggaggtagtagcattttcattaca agtgactaaaagaacagctgtttacccctgatcgtgcagcagtgcttgctgttccttagaattttgccttgtaagttcta gctcaagttggggggtggtgatagacatttaagaagccatatatcttttcagaagtaggtgtgatgtactaaaagtttga gacactttctagaagtctcactatttaagttatgactagtattggatttttggcatgtctttgggtttcatgtttcttaa cccaactgcctgcagggccttatggctgtcaggagcagttcttgggaattaaagtaattactgaagaagtattctagtga gaaaatgaatttatgactcagaagcccctaaagacatgggtactaagcaacaaaataagcagatgttaattaactgtaat tttctcttacagctgtttgcagacaaggtcccaaagacagcaggttggtccattttctaagtttaacaaagatgttccaa ttgtgacagtttgtgtgtgtgtgtgtatatatatatttttatgtatgtatatatgtgtttaatttttttttaaacagaaa attttcgtgctctgagcactggagagaaaggatttggttataagggttcctgctttcacagaattattccagggtttatg tgtcaggtacgaaatttactgaattttattttatttgggttgctcccttcatttgggattgagccagaatatttcaggat acacatatctgaactgttactctaccatttcggttctatttaacccttctattcagtttgaacttgggtttaaagtttga accttgcagatttggcacacttcatggttatgttgtcagaagtgacatttttcctatatgttgacagggtggtgacttca cacgccataatggcactggtggcaagtccatctatggggagaaatttgaagatgagaacttcatcctaaagcatacgggt cctggcatcttgtccatggcaaatgctggacccaacacaaatggttcσcagtttttcatctgcactgccaagactgagtg gtaagggtacaacatggcacactaaccacctgactaaatgaaaagttgccctggggggaacggaacaaacactacttttc ttcaacctttgcttccacagactttttcatccctaagatactagaagaagagcatacataaatgacaaatatagccaatg tgatacagaatgtcagatactatgatagaaacttggcccttagctgggtggttgaattaggtgctacttttttgagatgg agttttgctctgttgccaggttggagtgcagtggcacaatctgggctcactgcaacctctgcctcctgggttcaagcgat tctcctgccttggcctcctgagtagctgagaatacagatgtgtgccagcatgcctggctaattttttgtatttttgtgga gacggggtttcatcatgttggccaagctggtcttgaactcgtgacttaaggtgaaccacctgccttggccccccaaagtg ctgggatttcaggcatgagccactgcgcccaaccaattaagtgcttttttttttttttttcttttctcagactggatctc gctcttatctcccaggttggagtgcagtggtgccatctcagctcactgcaacctcctcccgggttcaagcaattcttctg cctcagcctctcaagtagctggaactacaggcatgcaccaccactcccagctaaattgtgtattattagtagagcgggat ttaccatgttgtccaggctggtctcgaactcctgggctcaagtgatctgcctgccttgacccccccgaagtgctgggatt acaggcatgagccactgtgcccacccaattaagtgctgcttttatgttactattaataacatgcggttggttgggttttt tgtttctttggggtttttgttttgttttgtttgtttttgggggaggggggcgcaattcattctatatgtgtaactctttt ttgagatggagtttcgctctgtcgcccaggctggagtgcagtggcgcgatctcggctcactgcaagctccgcctcccagg ttcacgccattctcctgcctcagcctcccgagtagctgggactataggcacatgccaccatgcccggctaattttttgta tttttagtagagacagggtttcaccgtgttagccaggatggtctcgatctcctgacctcgtgatccgcccgccttggcct cccaaagtgctgggattacaggcgtgagccaccgcacccggcctatatgtgtaactctttaatggtaattggagaatcat gtttaatgacatttagtacaaaaggcttcagttaaaaaaaaaaaaaaaaagctacctttctcgtcttggttcatgacaca tggaggctgcttgtttgtggttgccagtcataatgattgttcttccttttcaaggttggatggcaagcatgtggtgtttg gcaaagtgaaagaaggcatgaatattgtggaggccatggagcgctttgggtccaggaatggcaagaccagcaagaagatc accattgctgactgtggacaactcgaataagtttgacttgtgttttatcttaaccaccagatcattccttctgtagctca ggagagcacccctccaccccatttgctcgcagtatcctagaatctttgtgctctcgctgcagttccctttgggttccatg ttttccttgttccctcccatgcctagctggattgcagagttaagtttatgattatgaaataaaaactaaataacaattgt cctcgtttgagttaagtgttgatgtaggctttattttaagcagtaatgggttacttctgaaacatcacttgtttgcttaa ttctacacagtacttagattttttttactttccagtcccaggaagtgtcaatgtttgttgagtggaatatt (SEQ ID NO: 12058) gtgtactattagccatggtcaaccccaccgtgttcttcgacattgccgtcgacggcgagcccttgggccgcgtctccttt gagctgtttgcagacaaggtcccaaagacagcagaaaattttcgtgctctgagcactggagagaaaggatttggttataa gggttcctgctttcacagaattattccagggtttatgtgtcagggtggtgacttcacacgccataatggcactggtggca agtccatctatggggagaaatttgaagatgagaacttcatcctaaagcatacgggtcctggcatcttgtccatggcaaat gctggacccaacacaaatggttcccagtttttcatctgcactgccaagactgagtggttggatggcaagcatgtggtgtt tggcaaagtgaaagaaggcatgaatattgtggaggccatggagcgctttgggtccaggaatggcaagaccagcaagaaga tcaccattgctgactgtggacaactcgaataagtttgacttgtgttttatcttaaccaccagatcattccttctgtagct caggagagcacccctccaccccatttgctcgcagtatcctagaatctttgtgctctcgctgcagttccctttgggttcca tgttttccttgttccctcccatgcctagctggattgcagagttaagtttatgattatgaaataaaaactaaataacaatt gtc (SEQ ID NO: 12059) gaattccggagttccgggcgcgcgcgacgtcagtttgagttctgtgttctccccgcccgtgtcccgcccgacccgcgccc gcgatgctggcgctgcgctgcggctcccgctggctcggcctgctctccgtcccgcgctccgtgccgctgcgcctccccgc ggcccgcgcctgcagcaagggctccggcgacccgtcctcttcctcctcctccgggaacccgctcgtgtacctggacgtgg acgccaacgggaagccgctcggccgcgtggtgctggagctgaaggcagatgtcgtcccaaagacagctgagaacttcaga gccctgtgcactggtgagaagggcttcggctacaaaggctccaccttccacagggtgatcccttccttcatgtgccaggc gggcgacttcaccaaccacaatggcacaggcgggaagtccatctacggaagccgctttcctgacgagaactttacactga agcacgtggggccaggtgtcctgtccatggctaatgctggtcctaacaccaacggctcccagttcttcatctgcaccata aagacagactggttggatggcaagcatgttgtgttcggtcacgtcaaagagggcatggacgtcgtgaagaaaatagaatc tttcggctctaagagtgggaggacatccaagaagattgtcatcacagactgtggccagttgagctaatctgtggccaggg tgctggcatggtggcagctgcaaatgtccatgcacccaggtggccgcgttgggctgtcagccaaggtgcctgaaacgata cgtgtgcccactccactgtcacagtgtgcctgaggaaggctgctagggatgttagacggaattccttttgcagacgccac cgccgaggaaaaccgtgtactattagccatggtccgggaacgcaacatgaaggtgctccttgccgccgccctcatcgcgg ggtccgtcttcttcctgctgctgccgggaccttctgcggccgatgagaagaagaaggggcccaaagtcaccgtcaaggtg tattttgacctacgaattggagatgaagatgtaggccgggtgatctttggtctcttcggaaagactgttccaaaaacagt ggataattttgtggccttagctacaggagagaaaggatttggctacaaaaacagcaaattccatcgtgtaatcaaggact tcatgatccagggcggagacttcaccaggggagatggcacaggaggaaagagcatctacggtgagcgcttccccgatgag aacttcaaactgaagcactacgggcctggctgggtcagcatggccaacgcaggcaaagacaccaacggctcccagttctt catcacgacagtcaagacagcctggctagatggcaagcatgtggtgtttggcaaagttctagagggcatggaggtggtgc ggaaggtggagagcaccaagacagacagccgggataaacccctgaaggatgtgatcatcgcagactgcggcaagatcgag gtggagaagccctttgccatcgccaaggagtagggcacagggacatctttctttgagtgaccgtctgtgcaggccctgta gtccgccacagggctctgagctgcactggccccggtgctggcatctggtggagcggacccactcccctcacattccacag gcccatggactcacttttgtaacaaactcctaccaacactgaccaataaaaaaaaatgtgggttttttttttttttaata aaaaagaaggtgctccttgccgccgccctcatcgcggggtccgtcttcttcctgctgctgccgggaccttctgcggccga tgagaagaagaaggggcccaaagtcaccgtcaaggtgtattttgacctacgaattggagatgaagatgtaggccgggtga tctttggtctctttggaaagactgttccaaaaacagtggataattttgtggccttagctacaggagagaaaggatttggc tacaaaaacagcaaattccatcgtgtaatcaaggacttcatgatccagggcggagacttcaccaggggagatggcacagg aggaaagagcatctacggtgagcgcttccccgatgagaacttcaaactgaagcactacgggcctggctgggtgagcatgg ccaacgcaggcaaagacaccaacggctcccagttcttcatcacgacagtcaagacagcctggctagatggcaagcatgtg gtgtttggcaaagttctagagggcatggaggtggtgcggaaggtggagagcaccaagacagacagccgggataaacccct gaaggatgtgatcatcgcagactgcggcaagatcgaggtggagaagccctttgccatcgccaaggagtagggcacaggga catctttctttgagtgaccgtctgtgcaggccctgtagtccgccacagggctctgagctgcactggccccggtgctggca tctggtggagcggacccactcccctcacattccacaggcccatggactcacttttgtaacaaactcctaccaacactgac caataaaaaaaaatgtgggtttttttttttaataaaaggaattcccttgtaaggttttcttaacaaaacaccagtcacat aagtgcattttattttatatttttgtttatttatttgagacggagtctcttgtctctcaggctggagtgcagtggcgcca tctctgctcgctgcaacctccacctcctgggttccagcgattctcctgcctcagcctcccgagggggtagctgggactac aggtgcgcaccaccatgcccagctaattttgtatttttcgtagagatggggtttcaccatgttgtccaggctggtcttga actcctgacctcaggtgatcctcccgcctcggcctcccaaagtgctggaattacaggcgtgatccaccgcacccggccta ttttttgagagagggtcacactctgtcgtcccggctggaatgcagtgatgcgatcaccgcccactacagcctcgacctcc gggctcaagcaatcctccccgcccagcctcctgagtagcgagcgcctcgacgcccagctaatttttatttttatttattt ttttgtagagacggcgtctctctaagatgcccaggctggtggccggtgtcgaactcctaagatgaagcgatcctccccgg ccttggcctccgcgcctcctaaagcgccaggtatgagccaccgcgcctggcctacaagtgcattttaattaaagtattat taatgtctttgcctgaagaaattcgcttttaaattgtgacttatctttcacccaaaaatcaaagcacaattcagccccga ggcgggggcggtaggagctgggcggggcgggggcagggaaagaccaggagcagagattcaaaaagagtaagagggcaaaa tgtgcataatgcatcttcacaggtaagagcctggccaggctcctgttttaatggcttcctcctgaagaagattcaagcag agtgtaagatattttcggaaagtagagcattttgaaagcatttcataatctctcaaaaccggagactgctcctgtcccac ctcgttagagaaaacagcgatgctcaaaggcaacctccttcctgacattgcctggtaggacgcgacgtggtgtttgcccg cgcggaatgcggacgcaaggctgctcctaggtctcggggacgcgccatccccatttccgctcgcggaggcgtagggtccg ggcgcgggaccccagtcgaccttgactggcggcgcgaccttgaggcctgcgttcgcctcagttgccccctctgtgcaatg gggagacgcgcctcatcgcttgacaacggccgaagagccgccgcgcttccgtctcccgcgtgcgcgcgccatgctgccca cccccgttccgcactgaccctcccccgtgccccgcgtcccgtactgccgccccgccccgagtcccatgccgcagccaccg cgacggagcccgcaggcgggaacctgcctccgcgcgttagcgcgcacgcgcgcctcatgtgtcgtccccatcagcgccgg cttccgtctataggccagatgcactgtcactctggcgaagtcgcagacccgattggccgggacggaggcgcgagaccggg ttgcgggcggggccgaacgtggtataaaacgggcgggaggccaggctcgtgccgttttgcagacgccaccgccgaggaaa accgtgtactattagccatggtcaaccccaccgtgttcttcgacattgccgtcgacggcgagcccttgggccgcgtctcc tttgaggtcgggcgggcggcggcgtgcgggaatggggcccagaaagtgggccggggtcggggtgggtggtagcgccccaa aggcccgggcgcggggcgaccctgcttgaggggcgagcgcgggcgggctgcggcgccatttcctgacgaggggccatttt gggaggtccgcgagtcgcgggaggaggccgggacgcggcggacaaaggcaggcggggcggctgcgaggccgttgggggag ggggcccgcgtccgcccgcccgcctcatgtggccgcgccctgtcctgtccgacgcacgtgctcggcggccgcgctcaggt ccgcgccttgagagtcgttgtccgccctagcttggcctgggcgccgcagaccggagccagaagcacgctcgcgggggctt gcgaccgccttcctgggaagctgtcccctggcaggcatgggtgctttacatcctgagctgggaagctgtttgcttgaggg tttttctcaaggatcgaggcgcggtgtgagcccgtccatgctcggtcctgtagatcccgggaggccatgttataaaagga gacttgctgggatgtgacgggttgccacttgaaatatcttccatttggataaagtaggaatatttatacatgtgccccaa acgtccctccgtgtcccccacccccaagcggaaatgtgaaaatgggccttgcctttgctggtgcccaaggaccgccttcc actgcagtgacggcgctggcgggggaggcgctcttgagcccctcccgattgtccctctgcctagcaagcaagttgcgact ggccacaaggcaggcctcttccgaccaaggtggattaccagtgattacctaattagttttgagagcgttaaatgagttct taaagatcagttgtaattatagcatagtatctaaacttggcgcgtgtcttcaaagttaaatattgagtacgattccgttc cagttaacatggatagaccttagggagtagcgaaataggatgttagtggttttattcctttaaatcacatctcaaaaggc caccaatggctagtttggatcttattccgaaaatagattgatcctcatgcagtcttcgtgaggacagagcgatttccttg ttgcctaccctgtccatagtgcctggcacataggcactgaaacactgcatgttaatccacaccccaccccacctatgagt gtagtcaaagctggtaagtgacaagggctttcgtggaaacttggcctgacctaatgttgggcatcaggttacccaaagag cttcagggaaatgagaaaggacttgcaggtcttgatgagaatggaggggtaactgccaatgagggctttggctttagcga aagtctgaaagggaagccataggaacttaaacgtaccgactataaagctctgagaaaagctgatgttttagaaagaccat acattctaggtacaaatacctaaaaactaaaaaataagtacgttggccaggcgggcggatcacgaagtcaggagattgag accatcctgggcccctggtgaaaccccacctctattaaaaatacaaaaattagctgggcgtggtggcgcttgcctgtaat ctcagctactctagaggctgaggcaggagatcgcttgaaccccggaggcggaggctgcagtgagccgagatcgtgccact gcactccagcctggtgacagcgagactcttgtctcaaaaaaaaaaaagtacattgctataagagaagtgcacacggatac tagtagttaattcagtcacatctgtgaaatagcttataaaatgctacttttaaacaagctgtttttatgaaagggcttgt aaatgtttatggtatttaagctacctctctagccataacgtattatacattcaagaaaggttcaaaaccagatatactag aaaccaatctttattttttaccccactactaggtaagggcctggataccaagaagtgactgctcatctaatccataaagc tatgttaacagattggaggtagtagcattttcattacaagtgactaaaagaacagctgtttacccctgatcgtgcagcag tgcttgctgttccttagaattttgccttgtaagttctagctcaagttggggggtggtgatagacatttaagaagccatat atcttttcagaagtaggtgtgatgtactaaaagtttgagacactttctagaagtctcactatttaagttatgactagtat tggatttttggcatgtctttgggtttcatgtttcttaacccaactgcctgcagggccttatggctgtcaggagcagttct tgggaattaaagtaattactgaagaagtattctagtgagaaaatgaatttatgactcagaagcccctaaagacatgggta ctaagcaacaaaataagcagatgttaattaactgtaattttctcttacagctgtttgcagacaaggtcccaaagacagca ggttggtccattttctaagtttaacaaagatgttccaattgtgacagtttgtgtgtgtgtgtgtatatatatatttttat gtatgtatatatgtgtttaatttttttttaaacagaaaattttcgtgctctgagcactggagagaaaggatttggttata agggttcctgctttcacagaattattccagggtttatgtgtcaggtacgaaatttactgaattttattttatttgggttg ctcccttcatttgggattgagccagaatatttcaggatacacatatctgaactgttactctaccatttcggttctattta acccttctattcagtttgaacttgggtttaaagtttgaaccttgcagatttggcacacttcatggttatgttgtcagaag tgacatttttcctatatgttgacagggtggtgacttcacacgccataatggcactggtggcaagtccatctatggggaga aatttgaagatgagaacttcatcctaaagcatacgggtcctggcatcttgtccatggcaaatgctggacccaacacaaat ggttcccagtttttcatctgcactgccaagactgagtggtaagggtacaacatggcacactaaccacctgactaaatgaa aagttgccctggggggaacggaacaaacactacttttcttcaacctttgcttccacagactttttcatccctaagatact agaagaagagcatacataaatgacaaatatagccaatgtgatacagaatgtcagatactatgatagaaacttggccctta gctgggtggttgaattaggtgctacttttttgagatggagttttgctctgttgccaggttggagtgcagtggcacaatct gggctcactgcaacctctgcctcctgggttcaagcgattctcctgccttggcctcctgagtagctgagaatacagatgtg tgccagcatgcctggctaattttttgtatttttgtggagacggggtttcatcatgttggccaagctggtcttgaactcgt gacttaaggtgaaccacctgccttggccccccaaagtgctgggatttcaggcatgagccactgcgcccaaccaattaagt gcttttttttttttttttcttttctcagactggatctcgctcttatctcccaggttggagtgcagtggtgccatctcagc tcactgcaacctcctcccgggttcaagcaattcttctgcctcagcctctcaagtagctggaactacaggcatgcaccacc actcccagctaaattgtgtattattagtagagcgggatttaccatgttgtccaggctggtctcgaactcctgggctcaag tgatctgcctgccttgacccccccgaagtgctgggattacaggcatgagccactgtgcccacccaattaagtgctgcttt tatgttactattaataacatgcggttggttgggttttttgtttctttggggtttttgttttgttttgtttgtttttgggg gaggggggcgcaattcattctatatgtgtaactcttttttgagatggagtttcgctctgtcgcccaggctggagtgcagt ggcgcgatctcggctcactgcaagctccgcctcccaggttcacgccattctcctgcctcagcctcccgagtagctgggac tataggcacatgccaccatgcccggctaattttttgtatttttagtagagacagggtttcaccgtgttagccaggatggt ctcgatctcctgacctcgtgatccgcccgccttggcctcccaaagtgctgggattacaggcgtgagccaccgcacccggc ctatatgtgtaactctttaatggtaattggagaatcatgtttaatgacatttagtacaaaaggcttcagttaaaaaaaaa aaaaaaaagctacctttctcgtcttggttcatgacacatggaggctgcttgtttgtggttgccagtcataatgattgttc ttccttttcaaggttggatggcaagcatgtggtgtttggcaaagtgaaagaaggcatgaatattgtggaggccatggagc gctttgggtccaggaatggcaagaccagcaagaagatcaccattgctgactgtggacaactcgaataagtttgacttgtg ttttatcttaaccaccagatcattccttctgtagctcaggagagcacccctccaccccatttgctcgcagtatcctagaa tctttgtgctctcgctgcagttccctttgggttccatgttttccttgttccctcccatgcctagctggattgcagagtta agtttatgattatgaaataaaaactaaataacaattgtcctcgtttgagttaagtgttgatgtaggctttattttaagca gtaatgggttacttctgaaacatcacttgtttgcttaattctacacagtacttagattttttttactttccagtcccagg aagtgtcaatgtttgttgagtggaatattgtgtactattagccatggtcaaccccaccgtgttcttcgacattgccgtcg acggcgagcccttgggccgcgtctcctttgagctgtttgcagacaaggtcccaaagacagcagaaaattttcgtgctctg agcactggagagaaaggatttggttataagggttcctgctttcacagaattattccagggtttatgtgtcagggtggtga cttcacacgccataatggcactggtggcaagtccatctatggggagaaatttgaagatgagaacttcatcctaaagcata cgggtcctggcatcttgtccatggcaaatgctggacccaacacaaatggttcccagtttttcatctgcactgccaagact gagtggttggatggcaagcatgtggtgtttggcaaagtgaaagaaggcatgaatattgtggaggccatggagcgctttgg gtccaggaatggcaagaccagcaagaagatcaccattgctgactgtggacaactcgaataagtttgacttgtgttttatc ttaaccaccagatcattccttctgtagctcaggagagcacccctccaccccatttgctcgcagtatcctagaatctttgt gctctcgctgcagttccctttgggttccatgttttccttgttccctcccatgcctagctggattgcagagttaagtttat gattatgaaataaaaactaaataacaattgtc (SEQ ID NO:12060) gatctgtctagggctgtcagtggagtattgaagtcccccacgattattgtgttactgtctatctcatttcttaggtctat taataacaggtttttttgttttgttttgttttgttttgtttttttgagatggagttttgctcttgttgcccaggctggag tgcaatggcatgatctcagctcactgcaacctccgcctcctgggttcaagcgattctcctgcctcagcctcccgagcagc tgggactacaggcatgcaccaccacacctggctaattttgtatttttagtagagacaagggttctccatgttggtcaggc tggtcttgaactcccgacctctggtgatcttcccacctcagcctcccaaagcgctgggattacaggcatgagccaccgtg cccggcccatagtaactgttttataaatttgggagctccagtgtttagtacatatatgtttagaattgtgatatttccct gttggacaaggccttttaccattatataatgccctcttttgtctcttttagctgctgttgctttaaaatttgttttgtct gatataagaatagctacctctgctcacttttggtgtctatgtgcatgaaatgcctttctccacccctttactttatgtga gtccttatgtgttgttaggccagcatcaccctaatatcaaaaccagcaaaggacataccaaaaaagaacattacagacca atatttttgatgaacacagatgctaaaatcctcaacaaaatactagctaaccagttgcaacaacataccaaaaagataat ccaccatgatcaagtaagtttcgtaccagggatgcagaaaagcagcagatggtttgtgagttcttatctattctgcaatt ctgtagaaaagtggagcatttaggccatttacattcaatgttagtattgaaatttgaggtaccattgcattcatcatgct ctttgttgcctgcgtactttggtttgttttttgattttgctctttaacttgtatttttgttttataggtcctgtgtgatt tatgctttaaagagattctgttttgatgtgtttccaggatttctttcaagatttagagctcctttaaacagttcttgtag cagtgccttggtaatggcaaattctctcagtatttgtttgtctgaaaacgactgtatctttccttcatatgtgatgctta gtttcactggatgcaaaattcttgactgataattgttttgtttgaggaggctgaagatagggccccaaccccttctagct tgtagggtctctgctgagaaatctgctattaatctgataggttttccttataggttacctggtgcttctgtctcacagct cttaagattctttccttggtcttaactttgtataacctgacgacaatgtgcctaggtgaatatctttttgtatccatcgc ccaggctggagtgcagtggcgcaattttggctcactgcaacctctgcctcccaggttcaagcaattctcctgcctcagcc tcccaaggagctgggattacaggctcctgccaccacacccagctaattttttttttttgtatttttagtagagacagggt tttgccatgttggccagcctggtctcaaactcctgacctcaggtgatccacctgcctcggcctcccaaagtgctaggatt acaggcgtgagcccccgcacccgagccctgatattaatttttaaattaaaagactttatttttaaaagcagtttgaggtt tacagaaaaactgagcagaaagtacagtctctatataccccctactccctgcccccagttttccctgttattaacatttg tgttaatgtggcatatttgttacaatcagtgaatcaatattgataaattaaagtccatatgttagtgttcactctgtgtg ttatacagttctatgggttttgccaaatgtattaatatgtcatgtatccatcattacagtatcatccagcataatttcac tgtcctgaaaatgccctgtgctccacttat catcttttccccacttgctatcaccacaccaaagccctcacaaccactt a ctttttaatatatccatagttttgccttttgcagaacatcatatcattagaatcacaataatatgtggcttttcagac tggtttctttcactcagcaacatgcagttaagggtcttccgggtcttttgtggcttgacagctcatttctttttatcact gaataatattgcattgtatagatataccacagttttttttaaatttactcatcattaaaggacatcttgattacttctaa tttctggcaataatgaataaagttgatacaaaaacttttgtgtaggattttgtgtggacatatgttttcaactcattgag gtaaatgcctaaggcatatttagttttgtaagaaactgctaaactatcttccaaagtatctgtaccattttgcattccca ccagctatgaaagagtttctgttctacatcttcacaaacattggtgttatcagtgttttggattttagccattctaattg gtgtggagtggtatctcattgttgttttaattttgcaattccctaatgacatatatgttgagcatcttttcatatgcata tttaccatctgtatatcttctttgggcatatgtccattcagatcttttgcacatcttttcattgggttgctcattttctt attgagttttaagagttcttcatatatttttgataacagtcctttatcagatatgtcttctgcaaatattttctcccagt ctttgtcgtgtcttttcatttacttaacagtgtctttcataaaacagaaggttttaactttgatgaagtctaacttgcca attttttctttcatggattgtgctttgtgtgttgtatctaaaaactcattgccaaacacaaggtcacctctatgttctcc tatgttatcttctagaagctttgtagttttctgttttacatttataggggctgtgagaaggtgacagaggttacatgagg taataaggatagggccttagttgaataaggctagtgcccttataagaggaagagacgccagttttctctctctctaccat acgaagacacagcaagaaagtggccatctacaagtcaagaagtgggccatcaccagaaaccaaattactggcaccttgat cttaaacttcccagcttccaaaactgtgagaaataaatttctgctgtttaagccatgcaacctacagtataagttatagc agcccaagcagactaagacagaacccttagcatattaatcatagttactttaaatctctggtcccataattccaaaatat ctgccacatctgagtctggttctagtgcttgσtttgtttcttcaagactgtggttttttttctctttttagcatatctta taatttttctgttcaaagcaaggcatgatgtactgggtaaagggaactgaactgaggtagataggtgtttagaatgaaat ttagaggcaacttaagaaagtactcaaaaaacaaaattatgggagcatgctaaatggacacaggagccagcctgaaagag cttgcaatggacaaagttggaacaatttgagcaacaaaataagttattcttccttatagaggaattctaaataatttata tagatacttgccttccaggaagtggcacttaatccccatcaaaccctcataagtgtgggctggacttggtaacttccttc caaaaaatagagtatggaaaaggggtgaagtaacttcatagtggaaaaacctggcaaacactaccttggttagctgagca aagccttgatatggtgtgatgagaatggaatattacctttgtgatctttctctcaaacacttataatcccattctaatca tgaggaaagcgtaagacaaatcccaattgagggacattctacaaaatacctgaggagtactcctcaataggtcatcaaaa caagtcttagaaactgtcacagtcaagaagaaactaaggaaaaatgacaactaaatgcaatgtggtatcatggactggct cctagaacagaaaaagtcagtatataaaaactaagaaaatctgaataaagtatggactttagtgataataatgtatcaat attggtttattacttgtagcaaatgtaccatactaatctaagatgataataaaaacaataactctgtgtagggccaaagg gagggaagtgggctgatacgggaactctccgcactatcttagcaactttttggcaaatctaaaattactccaagatacta agcttcttttttaaaaaaaatcacaaaacctgaaaaattttaaagaaataaaaatttaaaaattaaaaagagtcaaatcc cagctgtatttttattaattatgtaatattgtacaagtcactctctgagctttggtgtccctgtttataaaagtgataga atacatttttgagtgacatctgaaagatagcagagtaggaagctccaggccctcctttccccatgtaatctgtgaaagga aattcaatttcgggacgccaaactcatttagcgaaagggaaaagtcaaagtgggaactgggtcatgcaaacctgcctccc acttttgggtcctcaataagatggctacaagatgaaaagctacatgcctccgccatattttgcccacaaggaaattccta gtgagttgttaaaatttcaccgtagcaatgcaaattgatagcttatctttacaggtgcagtcgcccccggcgcactagac ataaatgcacatctgagtgttcccctgccccattttgtccatgttatcttatgtaaaatgcatattccccacatttttcc tctgcctcttttatgtcatcttattaatgcagattccctgagccagacaaaggcatgaatgactatttttccctaccctc ctcttacatgaaaattgtgtacttctcagtatcgcaccctttcccctttaaattttgagccctcaaaatcatcttcggag acaggcatagacctgtctcctgagtgcatccttaactttggcaaataaatcccctaaaatgattgagacttgtcattttt ctcaattgacatctggtaaccacgaagggatcctgagtgaaagtgacccagcctgcagtagctcacctctcagtgcttgg caccggcttggtcaccttatagcccaaactgagaggacaatttgccaaagtcgaggacctctttccagggatctctgatc ttccaacattttccagttgggggtctgaagtttatttgctgttaaaaacaaaacaaaacaacaaaaacaacaaaaattcc tttttttgtaggcgtttccactcacttccatcaaggaaggcgagcctgtctgcttctgcatatgcagagagcaatcttca gcttgggcccccatcactaggtaagaaactggtttggaattctgtcttgcaaattcttttaaacgactagaattagcact aacaaccagctggtgttaatttcctgcttacccttagagcgctcagaaatcatataatttgcgtgatcattgttagtttt gtttaattgttttgtttctgggtttgtgtgtgtgtgtgtgtgtgtgtatatatatctgtgtgtgtgtgtgtgtgtgtgtg tgtgtgtgtgtgtatgtgtgtgtgtgtgtgttttggtcctttcccctatcggatttgaccaattctgaaccttcaagctc atgagtgtgaaattttccactctgaagaaacagaacacattgctcccctcagccctttggggcattctcaggcgactgag aatcacatgagggtttctgggagaaatgctccctaagacatgcagcagctctaaataggtttccccctcaaaagaacata cttagggtctaatctcagccagcagatgcatataaggaactgacccctcccaaactttgagcccctgacacactgtgcca ggtggccacaacgctggtggaccaaactggttcagggtgtaatggccctgtgaaaagctaggtttgcaagcagcacattt tgggtccaacacacatcccaacttggtcaaatccaaaggggaactctaaattatagagaacaaggcctctaagaccccag cagttgcagaatataaagttcccctcttagaaactccagcagggtatatgcaaaatacttatggtgaatcatcatgcaaa tatttaaccaagcggaccactataactaaagcagattctaagttacaatggcctaaatggggatcttttgagatgcccaa attagtgtacctgtgaaccaggatggagaatgcagacacaaaaaccaaacaaccagaatgggacagctattttcagtggt agctgcaaagtagcaaaagtggggaagaccactgtcacgcgtgtctgggtgaagtgaccaccaaacaggctttgtgtgtg caacaaggctgtttatttcacctgggtgcaggtgggctgagtccgaaaaagatgtcagcaaagggagttaggggtggggc agttttataggatttgagtaggtagtgtcaggaggcccgacactcctgtcttcttatattaataagaaaaacaaaacaag atagtggcgaagtgttggggtggcaaaaattttggggggtggtatagagagataatgggcaatgtttctcagggctgctt cgagcaggattaggggcagcgtgggaacctagagtgggagagattaagctgaaggaagattttgtggtaaggggtgatat tgtggggttgttagaagcaatatttgttgtacagaatgattggtgatggcctggatacagttttgtatgaattgagaaac taaacagaagacacaaggtccgaataagagaaggagaaaaacaggtattaaaggactaagaattgggaggacccaggaca tctaattagagtgcctaagggggttcagcgtgattattgcttggttggtcagttttggggctctatccttgagttttttt atgttgtcacataccaggccagattgatttaggtgaaaacaacactcttcatttaaaaatatagagtcccctttttttaa gcagtgagtaagcggaagtctcggtgattttggaggaaatagaaatgcaaagccagcaattgtttgttaaagaaggatta gaaacggctaggagagagtgagattgatagtgtggtggagatagctggggagaggtagagggtggcataagaatgggaac gagaataagagtgagtaaaaaagtaaagaataggacttcatcagggtgaaagtaccggactgtgccttgccactgaagat cttttatccacttcaagagagatttaagggtggtggtttgagataaaaccaggagataccagttatgatggtttggagga aaagtgtaaactgggagtgtaaacaagggcagggcatttatgagtagttgagaatggtgaataggagtatgactagacag aagatagtagggatgacaagtttttggggtgcagtccaagttgggctggtgtctggaatgagactggggcctaataaaaa ggagtgtccatacaggagctcaaatgggctgtaccctgtagcatcccgaggacaggcccaaattctgagaagggcaagtg gtaaaagtattgtccagtcctttttaagttggaggctgagcttggtgaggtgtgtttttaaaagaccattagtccatttt acctttcctgaagattgaggatgggaaggggtatgaaggttccactgaataccaggagcctgagaaactgcttgggtgat ttgactaataaaggccggtccgttatcagactgtatagaggtgggaaggccaaaccgaggaattgtgtctgacagaaggg aagaaatgaccacagtggacttctcagaccctgtgggaaatgtctctacccatccagtgaaagtgtctacccagaccaag aggtattttagtttcctgactcagggcatgtgagtaaagtcaatttgccagtcctgggcaggggcaaatccctgagcttg atgtgtagggaagggagggggcctgaacaatccctgagaagtagtagaatagcagatggaacactgagaagtgatttcct tgaggatagagttccacgatagaaaggaaatgagaggttctaagaggcgggctagcagcttgtaacctacatggaagaag ttatgaaatgatgacagaatagaatgggcctgtaaggctggaagcaaatattttccttggtccaagaaccatttgccttg tgtgggaagagattgataggtggaagtttcagcgggggagtaggtgggagtgaccaatgaaaaggagaaaaactggcagt gagggacagaagttggaatgctagctgcttttttagttatcttattagcataagtgttgccttgagcgatgggatctgat gccttttgatggcccttgcagtgaatgactagcttttttggaagtagagcagctttaagaagagtttttattaaggaggc attaattatggaggacctttgtgtagtggggaaacttttttctgctcatataacagcatggtagtgcaggatatggaagg catatttaaagtcagtataaatattaacacatagtccctttgcaagagtgagggcctgagttaaggcaatgagtttggct tgctgagaggtagtggaggggggcagagcagtagcctcaaggatagatgtggaagacactatagcttagcctgcctttgc cagtgattggcgattaggcctggtggaactgccatcaagtgtgatcagggtgaagaacaggaaagaaggaaatatgggga aatggagtgaatgccaggtggatcagagagatacagtcatgggggtcagatgtggtatcaggaataatgtgggaggccgg attgaagtccaggccaggaacaacggtaactgtgggagactcaagaaagagtaagtacagctgaaggagccagggggcag gaagtgtgaggaggaaaatagattttgaaagttatgggaactgtagagggttagtggagcatagcttgtgatttttaggg cctctaaaagtattaaagcggcagcaatgaggtgtggctgtagcctaggaatagtcagggaagcggataatttagttaaa atgtctcaatctaataagggagctgggcaggtggggataactaaaaaagagtgcataaaagaatgttgtccaagttggca ccagagttggggagttttaaggggtttagaagccttgctgtcaatacccacaacagttatggaggcaagggaaacagtcc cttaaaaagaaggtaatgtggagtgggtagcctccatattgattaagaaggggacggacttaccctccactgtaagagtt acccaaagtgtctgtgatggtccaggaggtttccgaggcgattaggcaatgtcagtcttcaactgctaagccacgaatat - ctgggaaggagtcagtcagagagccttgggccagagttccaggggatctgggagtggctgccaggcgagttggacagtcc aatttccagtggggtcccgcacagatgggacatggcttaggaggaatcccgggctgcgggcattccttggcccagtggcc agatttccggcacttgaagcaagatcctgggggtggcagtcctggaggaacgcctggctgctgcagttcaggtgttttga agttcttgtgtgctggagatgtggctggggtttctctcacagtggaggcaagtaattgcaactcagaaatacgttgctac ttggctgcctctactccattattgtccacattgaaggagaggttaattaagtcctgttgtggggtttgagggccggaatc taatttttggagctttttctaatgtcaggagcaggttgggtaataaaatgcatattgagaataagatggctttctggccc ttctgggtctagggcagtaaagcatctaagggttgttgccaaacgggacatgaactaggctggatttttatatttgatga aaaagagcctaaccactaactgatttgggagaggtcagataaagaaaaaggagaattaaccttggctatgccttcagctc cagccacctctttaagaggaaattgttgggcaggtcggggagggctagtcacagaacaaaactataagctggaccaggtg tgaggaggggaggtgataaaaggattatagggtgggagagcagaggctgaggaagaattgggacctggctcggcgtggca aggagcagcctggggaggaggggagaggtcagataggtccgtagaaaaggaggattcaaaggactcagagcttgggatgg agactgaaggaacaggagagaaagaagaaagatttgggacaagtcgcactgggagcagagactaaggagggatcaatgtg taaaagaatgcctggacgtcaggcacctcagacccatttgcccattttttgaccaaaatcatccaggtcttgtaaaatgg agaaatcaaaagtgccgttttctggctatttagaaccattattgagtttgtattggggccaagcagtgttgcagaagaaa ataagacgcttaggttttaggtcaggcgagagttgaagaggttttaagtttttgagaacacaggctaagggataagaaga gggaatggagggtggaaggttgcccatagtgaagaaggcaagccccgagaaaatagagggtagagacatggagaaggggg gtggtgagcagccctgggctgcaatgtgggcgagcagccacagccaaagcaggcgtccctgcaattgacttgccaccaag ggaatgtgggtgaatgaccaaggtaggcatccctgcggtgatcagacaccaatggagtgtgggtgaataatcaggcaggt gtccccgcagtgattaaacaccaagggaagactgtcttcctgagttcatgactggcgccggagttctgggtccatggata aaatgtgtctcctttgtctctactagagaggaaaaagaactagaattggaaggacagagagattgaagggtagcgagaga gggagactgaagggtggcaagagaggctggagaagagagtaaaaagaccacttacccgatttgaaattggtgagatgttc cttgggctggttggtctgaggacccgaggtcataggtggatctcctcatggagtgagggcgaggacaggggactggtctc ccaaaggagtcctcctgtcccgggtcttcggcaccaaatgtcacactcgtccgtgtgaagagaccaccaaacaggctttg tgtgagcaacaaggctgtttatttcacctgggcgcagttgggctgagtccgaaaaaggagtcagcaaagggagttagggg tggggcagttttataggatttaggtaggtagtggaaaattacagtcaaagggggttgttctcttgcgggcaggggctggg gtcacaaggtgctcggtgggggagcttctgagctaggacatttcacaaggtaatgtaatcagttaaggcaggaacaggcc attttcacttcttttgtgattcttcagttgcttcaggccatctggatatatacgtgcaggcttgggctcagaggcctgac aaccacctcatctccctacaggaggccaacaaacaacttagaaatgctaaccaagaactctgtaatcttgtatctctctt aaagaaatcctcagaattccttacttcccccttggtacctccccctacacccctactctaccctgaccaatctgaacttc ctggaccagatctgtccgccgcctctactgcatgtctaacacttgctcaacagaaggcagttcagagtctgactgcaaag accccaccccctcatgattccctgacagctccaatggcaacatctcatctggaagatgtggaaaagggggaccgtgcagg gatatctctcatgatcaccctattttgggaacaactgctaacaggtaggggaaccctggtaattgtctaccaacaccctg gtcaaaggctgaattccaaggcataaagaatttcctgacccccataaagatccaattgggtttgagtatttgagctcatt gtcagaacctatgacccaggtcattcagacttttatcagctagtccacatgttggtctcagaagctaaagctaaggaatg gctgggaaaagcacaatggtcagactctatagcagatttgacccctgaaggcccaatggagccacaacaaccagccccca caaatccagaagacaggcacaaagatgtgcaggaatgagcaaccactctattaaatatcattccttcagtgttccaaagg gttgtggattggaataaaatccaacaatgtcaccagaacccaaataaattagttttagattatttaacacattttgataa aactttaaaacaacattgtgggatgtcagctgattgctttgaaaacaataaaaatgatacattattaaatgcaaatttct taaacggactagatgatgatttagccacccttgtaaaacacaaattggaccacagccagaactaatgaactagttaactt agctgaccaattatcccgcactatgataaaacaaggaaaaacagaagattgcccaagttatgcatttacagctaaagcaa ttaacttctcaagcctctcggccccagaaagattttaagctccctcggtctgaggactcttccctcccagtctgttacaa ctgtaaatgaccgagacaccttatgatggattgccttaggctgaaacaaaagaaaaggcagaatgcaactcaggaagaca aggggtgctccaaggaaatacaggggtttcacctctccaaatattctaccctgacaaaccaattgggggagattaatata ataataaaccatgagtttacaactgccttaactgacataggtgtgactatctctgaaaaatcccaccttatttagaaacc ccattcctcagagtaatgaaagaatgaacatggtgggtatgtctaataaaatgatctcatgttttaagtccaaacccgta ccttagggttcatcaggttccactaccctgtcgcaggctctaagtgtgacacactcagtaggtcccatatgtttctaata tgcactggggcccctgtcaaacttttgggctgtgatctcaacatccataatgcccatatctctttttcatcaaaaggtga aacttttttagaattggagccaggagaccaaaaataccatatttaaaaatgtcctgacaacgtacaatttagtactagta atgttaaaatgtcatcttgtgaccaggaaaataaaatagagacagagaaggaaatattagggaagaagagagaacattgg aatacagagcaggaaacagtaaaactccttttagtttccccagtcttcctgttaacaccagaagcagagcacttgctcaa ggatgtgtcctcccacttatagtctcagtcaaatacagatacagagaaagtattctcagccattccaataaaggtagaga taaatccaaagaaacccctatccaaccttaaacactatcctctgcaaaaggaagccatagatggaattgctcctgtcata caagatta ctgagaaacgggctcattattccctgcacaatcccctgaaacagccctatattccctgtaaagaaactaag cgggagaggatggaaatttgtgcaggaattgagggcaataaacaatatcataattctcaggcacacagtagtccccaacc cacaaacccttctatcacctatatccactaccagccagtatttctcagttgtggatctctgcagtgccttctttagtatt cctgtagaaccagacagccaatatttgtttgtctttatttggaaagaatggcaatatacgtggactataatgccccaaag gtatacagaaagtcccacttagtgttcccaaatattagaagctgatttggagaattaaatattttcccagggctcaacat tcatctactctcctttgttcagacacactctcttcctctcaggaagatagtctatatttactcaaacagccaccaaggga cacaaatgtctaaagacaaacttcagctatgcttacctgaagttaagtatttgggacatattatctcagccaaaggactg agtattaaccctgatagagtgaggaattttagctttcccaatgcccgtcactaagaaacaacttagagtattttggggcc tggcaggctattgtagaaactggataccaaatttctcccttatggctcaacttcagtgtacatacctaaaaaatgaacaa cctgatcccatcatgtggactccggagggacaatcagctgtacaacaaataaaggaaattctgactaatgccccagcctt agggcacccgaactacaaattgcctttctcccttttcatacacgaagttggaggtactgcatccggagtactgacccaga aacatggtgatcatcagagacctataggctattatagccaacagctggaccctgtggctcaagggctgcctccctatgtg agagcaatagcagccacggcccttccgtataagtctgttgaagaaataattataggttccccccttaacatttttgtgcc acattctcttgagacccttctaaactctcatcatacacaacacctgtctgtcaactggttagcctcttatgaaattttgc ttttatcatctcccaatattactagttcctgctgtaataatcttaatctggccactctcttgccaggcccttctgacaaa accccctcatgactgtgttttgatgactgacttctcacccccaggacagacctacaagagatgccactggataatgctga gatagaatggtatacagatggatcttatttaagaggagaggatggaaattttatagcaggatatgctgtggtttccttac tagaggtaattgaagccaatcctctcccccaagccagatcagctcaagtgaccaaattggttgccctgaccgaagcttgt caattggcaaaagacaaggctgcaaacatttacactgacagccactatgcttttggggttgctcatgactgggatgttat ggaaagagagaggatatttaaccccctcagggcaacccataaaaaatggacaagtatcagagttgttagaagctgttcta acaccaaaacgcttggcaattataaaaatcccaggttggccaggcgcagtggctcacgcctgtaatcccagcactttggg aggccgaggcaggaggatcacgaggtcaggagatcgagaccatcctggctaacatggcgaaaccccgtctctactaaaaa tacaaaccccgtctctactaaaaatacaaaaagttagccgggcgtggtggtgggcgcttgtagtcccagctactcgggag gctgaggcaggagaatggcatgaacctgggaggcagagcttgcagtgagccgagatggcgccactgcactccagcctggg caacagagagagactccgtctcaaaaataaataaataaaattaaaaaaaaatcccaggtcactcaaaattagacaccaca gtaagtcagggtaaccaatttgctgaagccacagctaaaagagcagcattcaagccatcagccccaagttggaaaatggc cataaaacccaaaacacttaaatacatgttgaaagaaacccagagcatagctcctacaaaagagaaatctacttggaaac aggcagggggatacttgtctcccaaaactgaaatatggtgtggacctaattattccattccaagaaacccattattccaa tggaatgtcaggtgtcccttatgaaatatgttcataatctaacccattggaatccagataaaataatatcctggtgtaaa caatattactggaaaccatccttcacagtggcacaaaaagtttactctcagccgggcaccatggctcacacctgtaatcc cagcactttgggaggcccaggcaggtagatcacctgaggtcaggagttcaagaccagcctggctaacatggcaaaaccct gtatctactaaaaatacaaaaattagccaggcatggtggtgcgtgcctgtaatcctgcttcttgggaggctgaggcagaa gaatcgcctgaacccaggaggcagaggttgcagtgagctgagatcacgccattgcactctagcctgggcgacaagagcga aactccatctcaaaaaaccaaacaaaaaagtttactctcaatgtgttatctgtcccaaacataacccaggaaaacccctc catggggcccagggtcattttccccttccggctgaccttttgaggtatgacagcttgattttatccagctgccatcatct caatgttacaagtatgttttagtaatggtctgcatgttttatcattgggttgaagcttttccctgcaggcaagcaacagc cacgacagttggaaaaatcctactagaaaaaattgtcccactgtggggagtcccctgtgaacttcacagtgatgggggat catactttactggccaggttactcaaaatatttgtaaaatttggcccatatttcaacatttccattgtgccaccatcccc agtcttcaggcctggtggagaggaccaatggaataattaaaacacaattggctaagttcacagaggcatttcacctcccc tggcccaaagcactacccctagtgctgcttatactacgatccactccttttggaaaacatcaactgtctccttatgaaat tataacaggaaggcccatgtgtatgggaacgaacataaccaatccaacttttctccagggagatatattgcaatattgtg agggactcatttatcatcttagaaaaaaccaaaatttgttaaaaaattcctttcacggtgcgctccccgaagataaggtg cctggtcatctgcaacctggagatttcatctattggaaaagacatctaataaaggattcccttcaaccctgatggaaggg cccgtaccaggcactactgactaatccatgtactgcaaaattaaagagtatagattcatggattcacatctctcatctta aaaaggcacaacctcctgagtggactgtaactcccaccaaagaccttcacctccggttcactaaacatcaacctgcaacc caggattagaagcagacaacagctgttgtggactgcttaaacccaagacacagaaccaggcctgtatacaaagggaacgc ctctgtttattgtacagtaaccattacaattattgtcctagatataccggcaactgctgtcttataaatgacagggcact tgccttgtctgatttaacaccatttagtaactaaaatgaatttcgcaaccttgctattattaatcctatatccctacact ttcttgccactgccacccactgatgcccatgaaacaaacctgtttctacaatgggctcagcattatgcagacaaattaca aagaacacctgctggatatgcagactcatgcctctttccagtggctccagcctgccatggtggatatcccccttccaagg tcaggactggatagaataccaaaaatttatcacatcacagaaatggtctggtattcttagtgctgggataacaaaagaca atacatacaattggcccattaaaaacactcttaagaacaagggacatgggaaaagattttgaatggaaaggaccaggtca ttagctctcactttagcatccccccagctaaaacagaaggtggtaaccacaccccaaacaacagctcattttcaaaatgg aataatgcaaatttgggctggatttatctggctcacccgttcgtctggccaactcagccaaaattctcctctgtgctggg agaaagaaaccatatcaaggacctatggccaaacagtacgagagatacggggtggacacctggagaatgctgtgaccaca ttatcatattacaagacgctgactggaatgccaccgattgggtgcagcaatcaggtatttattggatagctccaaatggg acatattggctatgtggcactaacttatggccgtggttacctctagggtagttaggatgatgttccctaggttatgcttg ggcacaagacacgtaatccagaccctgccaaaaccagcaaacctttttcatttacaatttcattggacatgttaggtatt ccaatggtatgatcacttagctttaatctttgtaccacagacaggtattgaagatgttatatggcatatagaggccttac ccaattacatccaaaaggccctgaatgatagccacatgagtattgccttgctaagcaatgaggtcatgcttatgaggaaa gttgtgctatacaaccatatggctttagatatactcattgcagcacaaggggggacctgtgccgtcataaaaactgaatg ttgtgtgtatattcagatgaattgaagaacataactcgatttatgactgatatgaaaacccagataaccaacctgtcaga tctaaaaccctcactaatcaattggttgagtagttggtttggatcctggggaacttggtggcagaagctactgcttataa taggaataataataatttgtgttctgtcctgtttctgctacaatgttgttacggtatgtgcttgcaaataagttaatgca caactgaaagggctggggtaataattgcccagagaattgctttaattgaggaagcagtaatatagcttgacccagcttca aggtttgctttccttttgttgctataaatatgacctaggtccctatatatatatttttttctttttcttttttcctttcc tttttccttttttcctctcccttttttttttaaatattcgtgggacacaatttcctaggaatgagccttcctagcgacaa tgggcgtgacttcctaggaatgagccttcctggtgatgtgggacctaaacttctagaaataaactatcctagcaacagga aaccagttcagaaaagggaggaaaaatcaacctgtagccaagaacccatattccttttaaaatgcttccttcaaaagatt ttaaataaaaaaagaggggaaacctgaaaggaaattaaattttgggaccccccaaactcatttagcaaaaggcaaaagtc aaaatgggaactgggtcatccaaacctgcctcccccttttggttcctcaataaaattgttacaagatgaaaagctacatg tctcctccatattttgcccacagagaaatttctagtgagttgttaaaatttcaccatggcaatgcaaatcgatagcttat ctttacaggtgcagtcgcccctggcccaccagacataaatgcatatctgagtgttcccctgcccaattttgtctatgtta tcttatgtaaaatgcagattccccagatttttcctctgccccttttatgtcatcttttatttatttatttatttatttat ttatttacttatttattttgagatggagtttcgctcttgttgcccaggctggagtgcaatggcacgatctcggctcacag caacctccgcctcctgggttcaagcaattctcctgcctcagcctccagagtagctgggattacaggcatgcaccaccaat cccagctaatttttgtatttttagtagagatggggtttctccatgttggtcaggctggtctcgaactccagacctcaggt gatccacccgcctcggcctcccaaagtgctgggattacaggcgtgagccaccacgcctggcctttttgttgttatttagt tttatttcatatcataaacttaactctgcaatccagctagacatggaaaggaacaaggaaaacatggaacccaaagggaa ctgcaatgagagcacaaagattataggctattgccagcaaatggggtggaggggtgctctcctgagctacagaaggaatg gtctggtggttaagataaaacacaagtcaaactttaataagttgtccatagtcagcaatggtgatcttcttgctggtctt gccattcctggacccaaagcattccatggcccccacaatatttatgccttcttttaccttgccaaagaccacatgtttgt catccactcagtcttggcagtgcagatgaaaaactgggaactgtttgtgtccagcatttgccatggacaagatgccagga cctgtatgctttaggatgaagttcttgtcatcaaatttctccctgtagatggacttgccaccagtgccattatggcaatg tgaagtcaccaccctgacacataaaccctggaataagtctgtgaacgcaggaacccttataaccaaatcctttctctcca gtgtgcacagcatgaaatttttctggtgtcttggaaacttgtctgcaaacagcttgaaggagatgtggcccaagagccca ccatctatggtgatgttgaagaacaaggtggggttgaccatggctgatagtacggggctcctggcagcagcagcatctgt gaagtggccattctatgttatcttatatttaaaaaatgcagatttgctgaaccagacaaaggcatgaatgactatttttc cctaccccctcttacatgaaaattgtttacttctcaatatcctaccctttcccctttaaatttgaagccctcaaaatcac cttcggagaaaggcatagacctgtctcctgggcacgtccttaactttggcaaataaatctaaaatcattgggacttattt catcatttttctcaattgacaaaacatttaaaaaataatacagactggacccagcctgcccaactcccagtggagagcaa ggtttccttctattttcataggcaaccagaacaatgttctatgcacattttgtcctcagtaagagggcctctggccaaaa tttggctagcggcccattgggataagaagctaaccaaagcccctgtgttacagtgtaatttagagagcagcatggagagt atcatctcaccaaaggtgaagatagcattacggacatcaggacatctcttactgggagtagtttgaatctatcacaggaa agccaaatatcttcttgcagactgtaatgaagcattcattaagataaagatggctttttgatcaggtgttgacctgcctg aggaaaatcaggaagcagcttataacaccattactttacttgaataatttcatgactttgatcagccactgcctgactta gatgacatcgatgtggcccagaagttcagcctgggtcagagtagagtggaagaaataaccgtgagagaagaagttgggaa tatcagtattttacaagaaaatggttttggcgattttggaatggatgatcattgagatcagagaaagcagtgcttttgag gatgatgacatgttagtaggcactactgcttctaatctcctattagagtctgaacagagcaccagcaatctgaatgagaa aattaaccatttagaatatgaagaccaatataaagataataattttggagaaggaaatgatggtggaatattagaagaca aacttattagtaataatgatggtagtatctttgatgatccccctgccctctctgaggcagaggtaatgttgccagagcag cctgcacatgatgatatacgggtgaggatgataatacatcaatgggtgggcctgatagtcctgattcagtgaatcctgtt gaaccagccaactatgactgatcaaacaacacttgttccaaatgaggaagaagcatttgcattggaacctattgatataa ctgttaaagaaacaaacgccaagaggaagaggaagctaattgttgacagtgtcaaaaacttggatagcaagacaattaga gcccagcttaatgattattctgatattgttactactttggatctggcaccacccaccaagaaataggtgatgtggaaaga gacaggagtagtagaaaaactgttttctttacctgctcagcctttgtggaataacagactactgacgctctttacatgct gtcttacaccacttgtaccagaagaccttagaaaaagggggaaaggagggacagataatttggatgagttcctcaaagaa cttgaaaatccagaggttcctagagagaactagcaacagctacaccagcagcatgatgttattgataagcccattttgga agagccaagccatctccagaagtcagtgatgaggccagcagaacaaatctggatgagtcagctatgcctccaccaccacc tcagggagttaagtgaaaagctggacaaattaacccagagcctgtgatgcctcctcagcaggttgagcagatggaaatac tgcctgtagagcttccccaagaagaacctccaaatatctgtcagctaataccagagttagaacttctgccagaaaaagag aatgagaaagaaaaggggaaaaaaagatgatgaaggggaaaaggatgaagatgtttcagggggtgatcaagatcaggaag aaagaagatggaagaaaaggactcagcagatgcttcacggtcttcagtgagctcttgctaaaactggagctgaatctatc agtttgcttgagttatatcaaaacacaaacagaaaacaaactgttgcaaagttctacagcttcttggttcttaaaaagca gcaagctattgagctgacacaggaagaactgtacagtaacatcatcgcaacacccgggccaaagttccatattttatgag gagctagaagcattatagctagtgttcatttcactagtgcttacaaattgcccccatgtgtaggagacacagaacccttt gagaaaacttagatttttgtctgtacaaagtctttgcctttttctttctcattttttcccagtatattaaatttgtcagt ttcatctttgagggaaactgattagatggatgtgtttgtgttctgatggagaaaacagcaccctaaggactcagaagatt aacagttcagaacagatgtgtgcaatattggtgcatgcaatgatgttgagtggcagttgaaagtcatgatttttatctta gttcttcattactgcattgaaaaggaaaacctgtctgggaaaatgcctgacagtttaatttaaaactatggtatgagtct ttgaaaagaaaaaaaaaaagcctttccatcagtagtaacactggcaatcttcttgttaaccactctccttagggatggta cctgaaataacaaaggtcaccctcttgagattcgttttaagtgtaattccctaatgagcaaacgtgtacgtgaaattgtg ttgtgactgatacccttcagctacagataggactgacttggtttaaagtgttctattttgtaaatcattccatttgagtc tttctgatgaacttcgctatctcgaaatctgtcattttagtgaggctccaaaatgagcagaaataggcctgattagagta gagtgactatcaaatagcagactttctaggacctataaatagaagttttaaaaagatgtttggatatatttgactattca gatcatgaaaacagaaattaccctgcctactacaaggacagactgatgggaaattatacaccaggtcaacttaaccttta agcagacaatgctgtaaaaactaatggcttctctgatatttattgtaagttttagtactgatctccttttccagtgctgc acactcctgtgtttggaactttaatagctttgcaacgaaatcctatatccggtttcctataatttaactgaagaaaaaca catccaaataaaggtctatattaacagaccagatagcatcagaaatcatgtgactattatgattatcagaatatgtctta actttttagggcaaaattaacactgaaagttctagcttaagtgttgacactttcgtggggaaaaaaatcacttttgaaac agacttcagtgtatactcaataatttaaaattatgtgaaatgttttaaatttgtgaactcattactgttttaatgattcc gtttcttgagagtttaaccataaaaaattgctattgcagatttattttcaatatgctgtgcctgtaaaccatggagtttt ccctgtttgtaaaaagacattgtagataattgaatgtttgattttagaaaggtcattggtttcttgttacacattttgtt agtctgttttttttgcttattgggtttaatattgttcttgaaaatagttgatgctatgttatgtataactcttctaataa aagttgtgttataagttgaaacaaattatagtattacagactggctacaataactttataggaagtctgaaaaatactca aagttctatagcaaccaagcaaacacctagtcaagaaaacgatacagtcaaaatggttagaaattttgtgacatttttac ttgcctgtaccccatccttccctcctggcacacctggggaagcagcagccctgctcccaattccctccctggaaccccag agagaggaaagtggactttatttgcaacattctaacctgtcaaggggctgcctgaggtactggtctctgttttacctaat tcggaggtcagacagggaaaagcaacatggctggatactcaggctcaggaaaagccacaggaaatgatgggcactactca tgaacactgcagggggcctacaaactcacagatacctggagcaagagatcagaagtagaagaatacaatagaacatctaa gcccaccttctgagaagcagaggtgagactctttaggaaattgagacattttaagcagtcatgcattcaagggaactgga aaacaacaacaacaacaacaacaacagatacccaggccaaggcaaaatgcatagccaaaagaggtctaagaagaccttaa gacctcacatggggctgatcccaaagctgacagcatgccctgctaattagtgaaggtcttccctggcacagaacctactt gtaatgactagcagaggtggctgtttttttgaatgatcaattttaaaaatgaacaaaaaaataacaaaccatgcaaagaa acaggaaaatatggcccattcaaaggaagataataaactgtcagaaactgtccctgaagaaacacaagcatcagaagtac tagacaaagacaaaatgtcttaaatatgctcaaagagctaaatgaaaactcaaagaactaaaggaaatgagaaaaatgac acataaacaaaagagaatattaacaaagagaaactataaaaaggaaccaaacagaaattctggagctgaaaatacagtat ctgaattgaaaaacgcctagagggattcaacagtagattcaaacaggaagaaaaaagaatcagtgaacttgaagataagt cctttgaaattattgaatctgaagaccaaataataataataataattaagaaaagtggacagagactaagagacctatgg gataccatcaagctaaccaatatatgcattacagaaatctcagatggtgacgggataaagaaaggagcagaggaactatt tgaaaaaataatggctgaaaacttcccaaatttgaggaaaggcattgattcacaaatccaaaaatcttgctgatctccag gtaggataaacccaaagcagtacataccaagacacattatattctaacaaaagccaaagacatggaacactgcaggggga ctacagactcacagaaaccgggggcaagagatcagaggtaaaggaatacaatacaaagtctaaggccccctcaagaatct tgaaagaagcaagagaaaagtaactcatcatgcacaatggatcttcaataacattatcagtggatttctcagcaaaaacc ttgaaggacacaaggaattgaataccatatttaaaggaaattttttaattgttatttttccataagttattggagttcag gtggtatttggttacgagtaagttatttaatggtgatttgtgagattttggtgacctgtcaccgaagcagtatacactgc actgtatttgtagtctttcatccctcacccacctcccactcttccctccaagtccccaaagtccattgtatcattcttat gcttttgtgtcctcatagcttagctcccgcatatcagtgagaacacgtgatgcttggttttccattcctgagttacttca cttagaataatagtctccaatctcatccaggtcactgcaaatgctgctaattcattcctttttatggctgcacagtattc catcatatatatataccacagtttctttatccacttgttgattgctgggcatttgggttggttccatgattttgcaattg tgaattgtgccgctataaacatacatatgcaagttatcttttttgaataatgacttcttttcctctgggtagacacccag tagtgggattgctggatcaaatggtagttcacttttagttctttaaggaatctccacactattttccatagtggctgtag tagtttactttccaccagcagtgtggaagtgttccctgtttaccacatccacaccaacgtctactgttttttttattatg gccattcttgcaggagtaaggaggtattgcattgtggttttgatttgcatttccctgatcattagtgatgttgagcattt tttcgccatttgtgtatcttttgagaattgtctattcatctccttagtccactttttgatgggattgtgggtttttcttt cttattgatttgtttgagttcgttgtagattctggatattagtcctttgtcagatgtatagattctgaagcttttctccc actctgtgggttgtctgtttactctgctgactgttccttttctgtgcaaaagctctttagtttaattagatcccagctat ttatctttttattgcatttgcttttgggttcttggtcatgaaatccttgctgaagccaatgtctagaagggtttttccaa tgt atcttctagaatttttatagtttcaggtcttaggtttaagtccttaatccatcttgagttgatttttgtataaggt gagagatgaggatccattgtcattctcctacatgtggctagccaattaccccagcaccatttgttgaaaaaggtgccctt ttcccactttgtttttgtttgctttgttgaagatcagttggctctaagtatttgggtttatttctgggttctctattctg ttccattggtctacgtgcctatttttataccagtaccacattgttttggtgactatggccttatagtatagtttgaaatc agctagtgtgatgcctccacatttgtcctttttgcttagtcttcctttggctatgcgggctcttttttggttccatatga ttttgggaattgttttttctaattctgtgaagaatgatggtggtattctgatagagattgcattgaatttgtagatggct tttggcagtatggtcattttcacaatattaattctacccatccatgagcatgggagatgtttccatttgtttgtgtcata tatgatttcttacagcagtgtttgtagttttccttgtaaaggtcttttaactcattggttaggtatattcttaagtgttt tttttttttttttgcaactattgcaaaaggggttgagttcttgatttgattctctgcttggttgctgttggtgtatagaa gagctacttatttgtgtacattaatcttgtatgcagaaattttgctgaattcttttatcagttctaggagctttctggag gagtctttaggggtttcaaggtaaatgactgctatatataaagtttcagtggcacaaaagaaatagcactcaaatataaa attttctttttaattctcagcaaggctagttacttctctatagaagggtgtgcccttacagatggaacaatggtgagcgc acacttggacgaggggaagggattcttatccctgacacacatggcccctgctgctgttgttcccctattggctagggtca gaccgaacagactaaactaattccgaccagctaatttaaagagaatgacgg^'ggtgagtgctttggagggagtcagggcag agcaggtagcaggtaaatggaatgagttagggtggagcaggtgattggaatgtagggtggagcaggtgatcagaatgagt cagggtggagtaggtaaccgaaaaaggttgctttacgaggaagttaagtttaaaagtagaaggcaaagaattgaacatac tgacatattaattcttcgaaaagaaatttagaactcatatctaacatgatcatatcatcagcaaacagtgacagtttgac ttcctctttaccaattggatgccctttatttctttctcttgtctgactgctttggctaggacttccagtactatgttgaa gaggagtggtgagagtgggcatgcttgtcttgttccagttctcagagggaatggtttcaacttttcctcaatcagtatta tgttggctgtgggtttgtcatagatggattttattacattaaggtatgtcccttgtatgccgattttactcagagtttta atcatataggaatgctgggtttcgtcaaatgctttttctgcatgtattgtgatgatcatgtgatttttgtttttaattct gtttatgtggtgtataacatttattgacttgtgtaggtaaaaccatccctgcgtccctggtacaaaacttacttgatcat ggtggattatctttttgatatgttgttagaactggttagctagtattttgttgaggattttagcatctgtgttcatcaaa aatattggtctgtaattgtcttttttggttatgttctttgctggttttggtattaggatgatgctggcttcatagaatga attagggagggttccttctttctctgtcttgtaaaatagtgtcaaaaggattgataccaattctttgaatgtctgctaga agtctgctgtgaatccgtctggtcctggacttttttttgttggtaattttcttaattaccatttcaatctcactgcttgt tgttggtctgttcagggtatcttatccttcctgatttaaactaggagggttgtatttttccacgaatttatccatctctt ctgggttttctagtttatgtgcataaaggtattcatagcagccttgaatgatcttctgtttctgtggtgtcagttgtaat atctcccatttcatttctttccttttttttttttttgagatggagtctcactctgtcccccaggctggagtgcagtggtg ccatctcagctcactgcaacctccactcctgggttcacgccattctcctgcctcagcctcccgagtagctgggactacgg gcacccaccaccacgcccagctaattttttttctgtttttagtagagacagggtttcactgtgttagccaggatggtctc gatctcctgaccccatgatccgcccacctcagcctcccaaagtgctgggattacaggtgtgagccaccgcacccggccct ctcccgtctcatttcttactgagcttatttggattttctctcttctttacttggttaatcttgctaatggtctatcaatt ttatttgtctttcaaagaaccagcttttcatttcatttaccttctgtatttttgttcatttcaatttcacttagttctgc tctgatcttggtgatttcctttcttctgctgggtttgggtttggtttgttcttgtttctctagttccttgaggtgtgacc ttagattgtctgtttgtgctctttcagactttttgatgtaggcgtttagggctatgaactttcctcttagcactgccttt gctgaatcccagaggttttgatagttgtggcattattgtcattcagtttgaagagtttttaaatttccatcttgatttca tttttgacccaatgctcattctggaccaggttatttaacttccatgtatttgcatggttttgaaggttccctttgaagtt gatttccagttttattccactgtggtctgagagagtgtttgatataatttcaattttcttaaatgtattgaagctcattt tatggcctatcatatagtctatcttggagaaagttccatgtattgttgaatagaatgttttattctgcagttgttggatg aaatgttctgtatatatctgttaagtccaattgttccaacgtatagtttaaatccattgtttctttgttgactttctgcc ttgatgaactgtctatggctgtcagtggagtaatgaagtcctccatgattattgtgttgctatctatctcatttcttagg tgtattagtaactgttttattaattttggagttccagtgttaggtgcctatatgtttaggattgtgatattttcctgttg gaaaggccttttaccattatatactgtccctctttgtcttttgtaactgctattgcttcaaagtttgttttgtctaagaa tagctacccctgctcgtttttggtgtccatttgcatgaaatgcctttttccacccctttattttaagtttatgtgagtcc ttatgtgttaggtgagtctcctgaaggcagcagatagttggttggtgagttcttattcattctgcagttctgtatctttt aagcggagcatttagaccatttatattcaatgttaatattgaaatgtgaggtactgttgctttcatcatgctctttgttg cttgtgtactttggtttttgttgtttttgctttttaacttatatttttgtttcataggtcctctatgatttatgctttaa agaagttctgtttttatgtgtttccaggatttgtttcaagatttagagatccttttagcagttcttgtaatggtggtttc ctaatggcaaattctctcagcatttgtttgtctgaaaatgactgtatctttccttcatatatgatacttagtttctctgg atacaaaattcttggctgataattattttgtttgaggaggctgaagataggtccccggtcccttcttgcttgtagggttt ctgttgagaaatctgctgctaatctgataggctttcctttataggtaacctggtgcttctgtctcacagctcttaagatt ctttccttggtcttaagtttggataacctgatgacaaagtgcctaggtgaatatctttttgcgatgaatttcccaggtgt tctttgtgcttcttgtatttggacatctaggtctctcgcaaggccaggaaaggtttcctcgattattcccttaaacatgt tttccaggcttttagaattctcttctttctcaggtacactgattattcttaagtttggtcatttaacataattccagatt tcttggaggctttgttcatatttccttattcttttttctttgtctttgctggatggggtaattcatagaccttaaagctc tgaatttctttattctacttgttcagttctattgctgagactttccagagaatttcacatttctgaaagtgtgtccaaag tttcctgagtttttgactgtggtttctttaagctatctatttccatgaatatttctcccttcacttcttgtatcattttt tgaacttccttgtattgggcttcgcctttctctggtccctccctgattagcttaataactaacctcctgaattctttttc aggtaaaccaggtatttcttcttggtttggatccattgctggtgaagtactgtaatttttggggggtgtggaagagcctt gtattgtcatattactgggtatctcagccgtggataccagcacctgttccaatggaggtggcggagggtgcaatggactc cgtgagggtctttagttttggtgatttaatgctctatttttgtgctggttggtctcctgccaggaagtggtgctttccag aaagcatcagctgtagtagcgtggagagggactggtggtgtgcagggccctagaactcccaagattatatgccctttgtt ttccactacgagggtggataaggaaggaccatcagatgggggaagggctaggcgtgtctgaactcagactctccttgggt gggtcttgctaaggctgctgtggaggatgggggtgagattcccaggtcactggagttgtgcacctaggaggattatggct gtctctgctgagtcatgcaggttgtcagggaagtgggggaaagccggcagtcacaggcctcacccagctcccacacaaac tgaagggcaggtctcattcccaccgtgccctgaccaacagccccaagtctgtttccatgcggagagtgagaagggcttga aaacttgctcaaggctatctgcctcccagctgtgagagaaaagggctttaattcttctccctgcctgtgaagtatgcatg cccaattcacgccctccgctgagttctggccaggaggcttctcgccacattcaaattgttacaaagttcagctagagaat tccttctccctgtggagtttcaccccctgctcctctggccgatggatccctgtggtgccaggcaggaatgggctgcttgg gtcccagcaagttcctgggtcctctacctctgtatttcactcggctctctaacttgactcagctccaggtaaagctggaa acttcacctgcaaacagaccttcagcctctccagtgggggtgtgtcttcaggagaggagggtctacctttcccacttccg cagttgggaaactcacaggaattttttttttttaatgtcaacagataattctacatcttggaaaactgcccttcagaaat gagggacaaattaagacattccaagataaataatagtcaacattgcatgggaatttttggccagaacaattaggcaagac agaaacaaaaggcatccaaattggaaaggaagaagtaatattatctctgtttgcagaggatatgatcttacaggtagaac actgtaaatatttccccaaaatcactgttagaactagtaaatgaattcagcaaaaatgcagaatacaaaatcaacacaca aaaatgagttatgtatctatattggcattaaacaatctgaagaggaaattaagaaaacaattccatttacagtagcattg aaaataataatattcttagaaataaacttaaccaaagaggtgaaagacttgtacacagaaaactacaaaatgttgctgaa agaagctaaagaagacacaaatagatggaaatacatcccatattaatgagttggaagacttaaaattgttaagatgtcaa tactacccaaagtgatctacaaattcaatgcaatccctattattaaataaaatcctaattatgtttttgcagaaatagaa aaatcaaccctaaaattcatatggaaattcaaggaatcgcaaagaaccaaaacaatttcgaaaaaaaaaaatttttttta acttggtggtctctcacttcctgatttcaaaactacaagctacagtaatcaaaaccatgtggcataaagacagacataca gactaatggaataataaagagcccagaaataaacccttgcatatatggtcaaataattctcaacaagggtgccaagacca tccaatggggaaaagaaagtcttttcaacaaatggtgctgggaaaactgtatgtccacatagaaaaaaatgaagttggac ccttaccttgcaccatgcaaaaattaattcaaattcaaattagattaaagacctaaatgtaagagctaaaactataaaac tcttagaagaaaacatagggggaaattttcgtaacaagatttagcaaagatttcttgtatctgataccaaaagtacaggc aacaatttaaaattatatgagttggactccatcaaaattaaaaacttttgtatatcaaaggacactatcagcagagtgaa aaggcaacccacagaataggagaaaatatttgcatatcatatatgtgataagggactaatatccagaatatataaagaac tcctatgactcaacaacaaaaaaaacaaacaacctgatttaaaaatgggcaaagaacctgaacttcaaagaagttataca aatgaccagtaaacatatgaaaagatgttcaacatcactaaccactagagaaatacaaatcaaaaccataatgaaatacc atttcacaccccctaggatggctattataaaaaacagaaaataacaaatgttggcaaggatatggagaaattggaactct tgtgcattgctgtaggaatgtaaaatggtgcaaccactgtcaaaaagagtatgacagtttctcaacagatcaaacataaa attaccatgtatattagtcaaggttctccacagagacaaaaccaataggctatatatagagagaaagatacaagagggga tttattaggggaattggctcatgtgattatggaggctgataagtcccacaacaggctttctgcaaattggagaccttaga atgccagtagcatggccccattcaagtctgaaggcatgagaacccagggggctgctagagtccaaaggataaagagcctg gagtgctgatgtctaagggcaggagaagagtgtatcccacctgcaagagcgagaaaaatctctctgctatttttgttcta tcctggctccagctgattagatggtgcctgcccacattgagggcaaatcttccccacttagtccactcacactcacatgc caatatcctctgtaaacacactcacagaaacaccaaaaaataatgcttcacctgttctctagttattccttaatccagac aagttgacacctaaaactaatcatcacaccatgggacctagcaattccacttctgggcacaaaagaactgaaagccggga ctcaaagagatacttgtatacccatgttcatagcagtatgattcacaatggccaaaaggtgaaagcaacccaagtgtcca ttaacagatgaataaacaaaatgtgtatttatatataatatatatacaataaaatattcagtcttaaaaactaaagaaat tctgacacatggataacatagatgaaccttaaagacattatgctaagtgaaataagtcaaccacagagggacaaatattg tatgattctacttacatgatgtacctagagtagtcaaattcatagagacagaaagtagaacagtggttgttaggggctac gaggaggggatgggcagttagcatttaatgggtatgaagtttcattttgggaaaataaaaaaattctggagatgaatggt ggagactggcgcacaacaatatgaatgtacttaatgaccctgaactgtacacttaaaaatggctaaaatggtaaatttta agttatttatattttactacaaaaaaaaggtaacatactaaaatgatctcatgggttttgtgagaatcaaatgagatcca tgtagagaagccttgtagtctatatagcccttcgcaaatgttagctcttcttagtcattatcactccattttccccaatc tgataccattatccacacactttacccagccacacttacccaacagcacactgtttgagtttgagtgctatctggtgaat actcatcttcattttgctaaaccctggatgccatgtgctagccaacaa atcctattgttctggttcttaaacaaaacaa aatctcaaagacttcttcctcttacctagttttacccaatgattggctttgaagcagtccttattcagtaataagaggtc accatgccatggccaagaatagggcaaatcttcctccaattcagttgaactccctggccgtctagcaaacaacatatctc ataacacatcctttgagcaggtgaacaactctgaaccttctttgaaggaacaggattctgggaaaggaataaaagaaatg catgcagtgtgtattgagaataaaatctattagctaagaaataaaaaatgaaaatgctacaacatgatcagttttgatgg actagacaactctctgtagagtagccacagggctgaaccctcaaatattcccagaaagtatagacattgctgtagaacca gcctgataatgcagcagtgcagaacttaagaatgatatttctttctagaaagcagaccaattgatatct catcctgtta ttgatcagaatccacgtcagcattcaggtgctctctggctacaagtttccttagctcttgcaggcgctgctcattgaaga tttctcttaacacaggtaatgctaccagtctca ctggcacctttttcatgcaatgacaactatccaggagttgctgcct ttccagatatcccctgcgagaccaatgagggattttattccatgactctttgaagaggttcaaacatggatcaaacatga agtagtatgtaccccagccttagaaatttaatcttttatgactgggagaaagaacccaagtctctgtgccttcacagtct tgaatatctctgcttgtttcacttacgtttacctcactcaagattcttagtgtcatcgacatgactggttaagaactcag gacttttcaacaaagttttctgccagtgccccacaaatcatgactgtggtctcccaaattctttgattctccactaggtt ccctttctcctccattcaaagccccaaataacatttaccctatatatttagtcccgttttttgtagaaatgcttctttgc ttgtgttccccctaccttttcatatcatacctacatcgttaactgaggctcagtcataacatcaacaacagcatgaaaca tcccaccttctgtcttca ttgctataaactggaggcaaaggaaatgctgtcactcagggagtatatcaatgaagggaa agactctcacaagacaggcactgaggcaggagtcactagcacacagtgtataagtgaaatctaaatataaaaaagcaagc acttgggatacatcccttgcacacacctcctcttttataaccagtagagtgaagttggttgctgaagtcacagaatcaat agtctatttcccacagacggctgatgatagcagaacaagccctggctaagtcccccacccttttcttgagtagctcattg ttatgagccacggacccaccatcaccaggtcacatgttctgtactctttcctaaaaacagtgacaaaatatgctgagcca tccatatttcctcagttacattgagaggcaggagatataacaattaagcagtctctggagccagagcaacctgagctcaa accatgccttagcttgcttgttgtgggacctaggcaaagttactgaaacttctttagacatgtttatcaataaaatgggt acagttgactggctccaagatttcttgacctcttgatgtatttgccctgcataattcctaagactgtgattataatggat tttactcttatgattaggttttcacatagcacagttgactttaatacagggagattatctgggtaggccttgcctaaaca caagagccatttaaaagcagagttctccccagctggtcaaaagagagaatctctggtcagagattcacagcataagaagg tttcaatgtgccatcactggctctgagatgtagaaacccacatgtaaggaccaaaaagaagcccttaggagctaagagct acagccctccagccaatagccagcaaagaaacaaggacctcggtcctacaaccacagccaaccaaattctgccaacaaga aaaatgagcttggaagctgattcttctcccaaagattccagataagagtacaacaccttgatttcagccttgtgagatcc taagcaaagaacccactcatgtccacccaaacttctgacctacagaactgtgagctaacaaatgagtgttgtaagccact aagtttgtggaaatttgttacacagcaatagaaaactaatacaatgaggacacagcaagtgcttaataaatgttagcttt ta tat actaactcattgggatcagctacacagttgtaagaaggctaaagtaaaaattatttatgcaaggctggcagtg caacatagcattcagatccagggtccatttggtctaatatggctgatattaagtgtttctcaaggggagagacattattg gcattcagtggggggaggggttcatcctgtagaactgccttggacatggcagtccatttatcatctctggcttctcttcc cctagcagtagtcattgcaacaactgaaaatgccactgtacatttccaaaaatgctcctccacaagggttgagaactttg agaactactttaagggaaatttcataagaaagcatgcgtgtcttaaatgctgccataaagctacctcaataactacaatg ctactcaaattacctgaccctaagaatcgccagtggcacttgtttaaatataacgattcccaagttctttccctggagtc ccattccatagggctggggtggagccccaggaatctatactcttactcaaagaccccaggttaatcttttgtttatgtaa gtttgccaaacactgagttagaaatatactcagccgtacatgcatttagcaaaagttcaccacaacggaacaatgacaca ccaaaactctttgaaactgtgccttctacagagctgtaaatctccttttggaccattccattacacaaggtgtcctcttg gtcacacagtgattgcaaatgggactctagagtcatggaaatgggtatactcttctcaaactttccatctttaccagaat tacttcttaaagtgatatgcttcatggtgtaaactagcacttattaattttttctaaatatttatcatatttcatatact tttattttggagatggagtttcgctcttgttgcccaggctggagcgcaatggcagatctcggatcaccgcaacatccatc tcccgggttcaagcgattctctggcctcagcctcctgagcagctgggattacaggcatgcgccaccacgcccggctaatt ttgtatttttagtagaaaaggggttctccatgttggccaggctggtctccaactcccgacctcaggtgatgcgcccgcct cggcctcccaaagtgttggcattacaggcatgagccaccgcgcccggcccatatacttttaatacatgtggaattaataa aaacgtccatgcctccaattccgtggctattttaccgtcttcctttttcggacaagtccctcaaaggtagcgctcttggc tccttcctttgcttatcccctaaccctgtcctcctgaggtgccccctggatttcctccaaccccggcagggtctgccttt ccgggatgatacaacgacctgccctgcatgccatatcccaggcgcgtgggcaccaaagtgtggaaaaaccgatgaatgac gttttctgtttccgatactctgcctgccagaatcccctgccgcaccgccccaccacgaagcacatggaacccacggacta cacgaggacagaggtctgttctccctttacctctcccatttctttaactatgcttctctcggctggcatgccctttcctc atctcactccacacacgaacaggtttagcaaataatatgcacgctgctgggacgggcccaagcatttccctcccttgata gggcggaactaaaatgcaagccccacagttgtcagcaaaggacttccctgttaccatggtaaagccgctgcgcctttatt gtggttgaggagtacttgcatcaacctaagagaaaattaataagaaggaagtctgcaggctgaaacccttcaaattagcc tggactcgcctgcatctggctcggaacagagttaatctcaggagtgagaatatagccctccggtggacgcaactcgcgcc tgcggctaacagaatgtctccaggggaggggctctgcgtccgttccgcccaggcccttccggctcacgcgccgtacggaa gcgtgctcagcgctgggcttgtgctccgtacggaagtgtgctttggcgcaccggaagccgactcaacagagctatggcgg gtttgactgtgagagacccagcggtggatcgttctctacgttctgtgttcggtgagaggaattcgttgtagtcaagcttc ggggagggactcccctctgcaccttctatctcatgaatcgctaccggagccgctgacggttcggacgtgcagttctccct gcttatcctgtagggcgtccaacctggtggactcatgagcaaagagatattcccattctgccgaggtctcgtaggctttc cgcaatatcagtggggaagttagactagcgttcagcttctgtgcgtttctcctttcatgagcttcaattattctctagag gagaaggctcacggtaacagctcctcactgtcccgtactacttctcatcctctgccccagaatacagactatatgctgag ggtatagatcctagtgtccacttactgtcctctcctaaggactttcatcctttgctttttatctgtaacattttagtgca tcaatagtggtagcggccacctggtgtcctgagatggcttgtaagtgaatgaatgaatgaactattaagatctcctcaga ggaattttaaaaaggatcgaaacgattctgaattatctttttggctgaaataagttgtttttaaaaatacgtgtgattat tttagagtaccatttgaaagggacatgacaaagtagttcagaatactttttaaacatctttcactacattcatcgtcatt ctcccttaaatgttgtatgtgtggaaatacataggaacctgttttaaaaattatattaaataacattgatattttttgta gtcactgatgagacttgcagatctttaggtaaataccagtgccaaagtatttatttgcaccaaagttaaggaaaatctaa cacgtgtcagatcagtctgagaactaacatttgagagtacctacacattttgtatttagtttcagtggtatatttccttt gttaagaggtctgaagaaatacaatggaattgggattggagaacactattttgagtcttatatttgatgatataagttta ctttctcactaaagatctatgttataaactcagaattttaatgttacctattttcttccttagtggggaacattccttat gaagctactgaagagcagttgaaggacatcttttctgaggttggacctgttgttagtttcaggtgagatccccttttcct tcatggtgggagcttcttaaaaatcaccacagatttggctcttagtaataatggcaggttttctttactggtgacttttc acatacattttgttcttgtaacagctttattgagatataattgatacactatacaattgacatttattcttacctaaaat atgtttttttcgttaaaaatgttttttaggcagggcatagtgactcaagcctgtaatcccagcactttgggaggccgagg caggcggatcacctggggtcaggagttcgagaccagcctgaccaatgtggtgaaaccttgtctctactaaaaatacaaaa attagccgccgtggtggcccatgcctgtagtcccagctactcaggaggctgagacaggagaattgcttgaacccgggagg cagagatagcagtgagccaagatcatgccactgcactccagcctgggcaacagagcaagactccatctcaggaaaaaaaa aaaaaaagttttaaaaaatatttctgtgaggctgtcagagatataaggttatttatgttacagtgggcccaattaaagca tggcaatgttagcaggaaccctgtatgtgtgtaacatttgttcctgacacttggttctgctctccagattggtatacgat agagagacaggaaagccaaagggttatggcttctgtgaataccaagaccaagagacagcacttagtgccatgcggaacct gaatgggcgcgaattcagtgggagagcacttcgagtggacaatgctgccagtgaaaagaacaaagaagagctgaagagtg agtacaaatccaacttggatgcagtatgagttagtaaagatgtaacaatgaagattttccatttctgatatgttttagaa tatgctgaaatggttagccacgcagcttgtttattacttgactgacctgatgtgcctgagttaggcaagtattatatata tctttttaaaaactttttataaattttttttcaagtaattgtctgaaatttctatacccttgctctggatggagcagggc aaggcctcaaaccgtttcaaaactgttctggcaagcactgtagggatgcatagggtcactgcagacctaagcatgctgga ggcttgctagtaagtgtatatctttaagaaacagataaagttgacattagaaattcttcagttgctccagcctgggcgac agagtgagactctgtctcaaaaaaaaaaaaaaaaaaaagaatttccattgctaaggagttatttccagttaaagatgaat tcaaattcatcaagccattagtagtactaactgtggcattagtcattcctgtcactcttttcaggaatttttgaagttag cgtatttttctcttttaaccttttgtttctgaaatgacttgttaaaagaagtcaatgtgcctagttctctaacttaggtt aacattgtccttccatgtgatcatgatccccagctttcctctgagaacagaaaatacactctcactttcctccacagaaa caagaggctttcacatcatttatttctcagctctggagaatctaaaattatcagctggttcttacagcagccctgaaaag tagatatttgaaatgatttagctttttgttttgcctccctaactttcttgtactttcttcttgattaggccttggcactg gtgcccctgtcattgagtcaccttatggagagaccatcagtcctgaggatgcccctgagtccattagcaaagcagttgcc agccttccaccagagcagatgtttgagctgatgaaacaaatgaaggtgggaggaggcattaggttatgaataaagcaaat cacatcaggttttcaaggagttacttgaattagttccctgagctcaaatagaaattgtctgtagaccaccatttcttgca ccttcaatattctgtatgtacacagtatattttacattttgtacaaagagctttctatttttgtacacaaacacagctat ccaaacaatccagctggagttttgtggcccatagatgtcagatgtagatattaaaatttggcttttttcctaaatgataa tatcacagtatttgaaatgcctctttcttctcttgcctgccatgaccaaggtttttttgtgccatgcaaaaactaatgat aaagagcctcttgaatattacatttctcagaggggaatggctctaaatcactatcagtttctaagtcataagtattaaac ctgaatctgcttatcttctcagctctgtgtccagaatagtccccaggaggcacggaacatgttacttcagaaccctcaac tggcttatgctttgctgcaagcacaggtagtgatgagaattgtggatccggaaattgccctggtgagtgcttctggttct tttatggaaatggtcgggtaaaccttgaatgggataggaactacctgattgctttgttaaacagacagctcat ggtttg tcttttcactttttagaaaattctgcatcgccagacaaatatcccaacgctgattgcaggcaaccctcagccagtccatg gtgctgggcctggctcaggatccaatgtgtcaatgaaccagcagaatcctcaggcccctcaggcccagtctttggtaggg ctttatcccttaacatttttttgtatctgtcttagaatgtcattttctttttaggagaatat ttgaaagaagaatggtc aggaaccagagatgataatttcaatttccaggcataaaagcaatttccaggttgcagagcacatgacatctgaatgaata tagattcgattccaagtttgtaaaacaaagagatccttcccgtatgcccttttcttataagctaactttgtgtgtatgtg catgcctggcactgtggttggcacttcgttattccatatgcattatctcatttaatcctcaaagcaattgtatgaggttg gcactcttattatctccattcttactgatgaaaaaagtaaagcttgctttcaaagcatgacacaaaaccttaaagccata aaaaattgatacatttgaaaactaaaaaatttctatataaagaaaaaaataagtatcaaagacatgacaaattgagaaaa agtatttaccacacatgtgatggaaaacagactaataaagagcccatagtcattcacaagaatgtttattgccttagagt gaaaaattggaaatgtcctaaatgtacgtcagtggaagaatggagaaaatgtgtggtacattcatccagtgaaatactgt acaacagttaaataaactacacgtatcaacatgaatgactttgaaaaacataattccatacagcagttaagatgaactag gatacataatatcaacacaactccaaaacagtgacatacggacatgaaactaagtgaatatggatgcattcccgaaatgt aggatatatgtttctgcataaatccccaaaatatgtggaatgagttgcaaaataatatattgagtatgtaatgattcata taaaattttgaaacattaagaagacgtcttagtggtcatcaaaggagaagagagcacaggatgcaattggggaagaccgt acaggccattggtttattttatttacttatttatttcctaagctgggtggctattttattttctatatgatttgtatatc tgtaatttttcataataaattttaaaaggcctcctataaattagtaagaaaatttccaataacccagtagaaaaatggga aatagacataaatatttcacaaaaggagaaatataaatatataaaaatttattcaacttcaaaataagataatgtaataa attatcatttatatatgtaatgttataagataatgtaaatagaaactacaataagctaccatttttcatctctcaggttg gcagaggtacagggcagggaccagcaaacatttttctgtaaatgatcagacagtaaatatttttggctttgcaagtcaca ggatctgccacagctactctgccatggtagtatgaaatcagccataggcaataagtgaacaagtgtgtgtggttgtgttc cgttaaaagtttgtttataaaaccaggcagtgagcccgatttggcccatgggtcatagtttgccaacccctgctctaaat aaataaatacattttcagagatagaaaaaaaaagctaaggcccagagaggttagctggtccaaaaattgacacaattata agtggcagatctatttctgaacctggttttatctgacctcacagccagttttctcttaactactttcctatacagctctt ccttttcttttgtagagttttgtgttccttaaacgtatatgtgattttttttatataacttggcttttattctttattta ttgagctgtttctaattcaagggactactcagttttttggggaatgcacagatgaaaagatgacattctctttttctcaa cgagttttaatgtagcatttaaaaaaatatatttcacattcccccaaaaccagaattatatctaaggacaggagtgagaa aagattggttaaattaaaaaaaaaatttaattttaaaaatgtggactaccagcagttgttttttttaaaagagtcccagt ctccttttatgtttcttgggtttagggcttttttttttttttttttttactcttattggcagccccaatcatgaagttaa cagtaggtgttatgtgctgccttgccacacagataagacttgtcaatctctacattgagaatatgttccatcttaaccgt gttccatataaccaggctcatgacgtatattgcttctgtggagtttaaagtgtgtgacaaatctaatgctgcataagaca tgccatacaaaaaggatgtttagtagtgtatttggggctgttcatttgaagaggacttttaaggtcgtagacttagtata ttgagtatccacagaggcatatacatactctgttttttttgcttggtcagggtggaatgcatgtcaatggcgcacctcct ctgatgcaagcttctatgcagggtggagttccagcaccagggcaaatgccagctgctgtcacaggacctggccctggttc cttagctcctggaggtaagtttcatttagtcttcaccatttcagtacttgctaaagttttgtcatagccactgttgcagt gcagccaaatatgataatgggatccttaggtaaaattaatacacagctagaaagtatatatcttaggtggaggaaatagt agatttcttacgttaaatcctgtatgtctaattataagaacagggaaagggacagtaaagtgaaagagcatagtaaaact tccaagttaacaagggggaaaatggaatgagtggaaacaaaatcaagccagcaaaaatagagaagaggaaaaaagtaaga gacagtgtaaaataagtaataataaatgtagagtaagatggaaggaataaaaactaatgtagttgttactctgctaaata tgaatgaactgtcagattaggttcaaaagctcatgaagaaaacagacaaaaaaatacaaggtcacatttgttatagcata ttaaactgacataaaattgtattttaacaaacataatcagaacaaacaacaaaagggaaaaagagaaatttaaaagctat gtacatttattgaaaatgtatagatcggcaattaataagagtattgctcatatacttgtaactgttccttgttcaacaat tgtaactaagaagattgagtgaaataatgattccccatatgaaacatctgtatgaacacatgatgtattaccaatattta aagtttttttatgtaacaaacttggtttttgttaatttatctaatctagggtaggttgagtacaacactactcatggaga atgatttaattctaaattgttctgttctgtagagaatccagtctgcagagctaagttgatgaggaatggaagaagagatt ttttgaagaaatttctgcaaactcaggaattttttgtatctactttaggattgttatgtatctactttatcctaatagag ttatacttgtatttaaattatctttcatgacaggaggtccatgggtaagtgacattgttttcctgtattatagaagagct tcctgccaagagtttggtaaccaatgaaatgaattattcttattgaactcactattctgtcactgaaacataaagtacaa attgtaaatatactaacaaaccccatcttctctctcattgcattgttgaatatcttcctttgtaggtttctgcttgtgga gcagaatgaggaaatttgtaaactcagccactgttctaatttttcttttccgctgttctaattggtgttttttcttgtct gccctttatcttctaggaggaatgcaggctcaggttggaatgccaggaagtggaccagtgtccatggaacgggggcaagg taaataaatattaatgtctgactaatgttaattggtcatggaagtgttccacatccacagtatctaatatggcagccact aaccacccatggctatttcaatattaagttaattaaaattaagtaaaatttaaaactcagttcctcagtcacaatagcca cattccaagtgctcagtggccacaggtgactagtggataccatacaggacattacagatatagaacatttctatcatcgt aaaaagatctattggacagtgctggtctagactttccacctggtgattcagagtccagctctacaagaattgataatgaa gcaagtggatcgtttgtttcctgattcctagtctaataattccactgacatgttctctctccctgtatggatatctgttg actgagtaaggaattttaataatgagcatgtaaatatgtggctgggtatgtagaagactagatttaaaccccagagaaaa ctgggagggaatcataggtctgtaacgcctacttaatgaacatatgttgtaccgtggctgtactgctatatacaacagta gctgctgctccaaaatctccatgttgtttcttcatgttactggagtttgaaggacaagaaagtgcagtggttcagttgga aacaatgttaggaggagagatcgtaagaaaagagaaggaactgagtgcatactatatgccaggcactttaattttcataa ataatcttgtgagttaggtggcagcacctcagttttacaggcaaagagttggaagctcagaataagttactttctcaagg ggacaaggtaagtaaatattaatgtatgagtaatgtggactggatttggtgctcttattttctcttccaactagtaagtg gcagagctaagattcagaagtctttgactccagaatctgtcctctttctgtcactccacactgcctctgttaacttccaa gcatattcttcagtgtcttctactcttattccttgggaataaaatgatgggaaagactgctttggacaagcatagagaag cttaaggttttttcttttgtagcatatggtttataagtggaacccatttaaaaagcaaaatattggccaggcgcagtggc tcatgcctgtaatcccagcactttgggaggctgaggtgggtggattgcttgagctcagaggtttgaaactagcctagaca acatggcaaaaccccgtctctataaaaaatacaaaaactagttgggcaatggtggtgtgcacttgtggtcccagctactt gggaggccgaagtggaaggatcacttgagcccaacaggttgagactgcagtgagccataatcgggcaccactgcactcca gcctgggcaacagagcaagaccctgtctcaaagaatatatatatatacacacacacacacatatatatacacacatacat acataaacattaatatacaagcctgtggtttttacactggggttggttgctgaagtgacagaattaactttttcttgtta gaagtctgacagcaggacaaactccctggccaaatatctcatattttctctaagcatccaatgcttttgtgctattgtac atccctctatccccaccgcaccactgtcaatagatcatatatgttccccagagtatttctgcagtaatgagaaggtatta gggtttcagtcatacttctgcctgtcatggggccagccctcaatccatcaggttttagctgtttaacgcatacttgcaca agacatcttcctattatagtt tcttcacctttttgtcagaaattggcaaagggaagtgactcatgttttgagggtattt ccaggatgtcttcatgcagagactaagtgagatgagctttcttttatagtttccttcagtacccagcagaggaagcaaga gtcttttcgtgtgtgcctagtttgtcttacttttcctgaaatccatgctgcttttaatgctgaaaggagatggagatgtt tgagaagatacttcttgcttccctgccatgtttgtttagtgtcggttcccatgtcatctcattagtctttgtttgctgtt gtcatgatgtttattatcaaagacttgctgtggcagagtatttcttgtggagtgatattctctttcatcatgtaaagttc attcactgcatttccccatctgatacatttttgacagcagaaatttttgtgctttaaaatgtgacaaaaatagaattgcc gtacttcagttatggccgtttcagaatgaatcttgccttccagattcagtgcagtttcttttatgttttgcttctgaaac tacatt atgttctttgcataactagaagattcaaaactatcctttttatatatttttttcctaatgatttcataaggag acctaacggaaaactagtagcagaggtgaaaatcgaaaatgtcaggttattcccacctagatcaaaccagtgcccccatg ggattccctttcaaaagctatctggtcaaaatggaactatttcagagacccaaaggagctagtgtagtttagggagattt tgtagcctggagcaagccgatgaactcttggctttttaacttatatatgtaaatctcaatctccatgtgtgtgtgtttct gcgtgtgtatgcaagctattttaagtgtctgctctttctccttttgaacttactgcttacctaggaaccctacagcactc gcccgtgggacccgccgggcctgcatcaattgagcgagttcaaggtacccattgtatctgtgggtttccttttgcttgtg gtgttcagggtgggacgttgagaggaaaagagctgcgtggcagtcatcctcgcgttcagaacccaaaagggtagtgtttt tgggtttttgtttttttaattttttcctgttgaggccacaagcctaagattgacctcttcacacagggcagagaacatgg atgatatgggcatctgtccgaggctgtactccctccctactggtgtcaggaggcttggatggaatagcagtctgtaagga gacagcgggttcttgcagagccatggcagtgttcacatatgccaagactctacctctgttttgtgactctggtccttgaa ctaagattgattagaaggaaaaccaggagcataagtttctccaggtcgcagtgctagtccttggcaggttgctccccagt ttgctctttatataattccatccatacctctgacatggcacagattctgcctacaccctgcttctgttcttgagctgcaa gaggattctgctgtggtgaggtttcacccactctaaggtgtctgaattatgttgtcagtggtatatagagtcatttcttg tttgcttatgtgtctttcacagcagtaactccccgtttgtttccctgtcagtgccgatgcaagaccccagagcagctatg cagcggggatccttgcctgcgaatgtcccaacccctcgaggcttgttaggagatgctccgaatgatccacggggaggcac tttactttctgtaactggagaggtagagcctaggtaagcactaacatagaaggaaacagttgaagaaatcagaattgtcc cttcttccctgagaacaaaatctttctgtaccagttgtacctgtttgcctacttcaaaaggtagatcaatattcatggcc actgtccaagggtaagcacttctcctaaggcagaactatgtacttgagtatgtcattttgagctattatatttttagaaa ttggaaattttagtatacatacttgaacagggaaatttatagtagtggaaatattaataatagcaataataggccgggtg cagtggctgacgcctataatcccagtactttgggaggccaaggtgggtggatcacttgaggtcaggagttcgagacctgc ctggcctacatggtgaaatcccatctctactaaaaatagaaaaattagccgggcgtggtggcgggcgcctataattacag ctactggggaggctgaggcaggagaatcgcttgaacccaggaggtggaggttgcagtgagccgaggtcatgccactgcac tccagcctgggcaacaagagtgaaactccatttcaaaagtaaataaataaataaaataatgatagtaataataattgaca ttaatggggatcatgcctctgactctgctctgagtactttacttagatcatcttattaaatccacaagatcctgtgagat ggataccattattagtcccattttacacgtgaaactgatgtgtggaaaagttaaataatgtgtccaatatcacacagcta ataagtgatagagcctagatttgaacccatacagtctgaatccagagctcatgttcttatgcattgttctgcaaactcat acatataatgaatattcgttgattcctccctaattatgaaccaaataacgaaattctagaatacatggatttatatctct gtagcttttcttccatctatttggtgttattttcttgttagtattcatagactacatcagctctttgttggatgtttact tactgatctggttggtactttgttgttgttttgttctattttaaaatacaacgtttttctccatctccagaggttacttg ggaccacctcatcagggtccacccatgcaccatgtccctggccatgagagccgaggaccacccccacatgaactgagggg agggccattacccgagcccagacctctaatggcagaaccaagaggacccatgctagatcagaggggtccacccttggatg gcagaggtaaggggagatcacattgcaaatgccataatgaactcaactgtcttaggctctaatctgggataaagaatgct ggaacagtaggtttgcaagcatctttaaggtttatccacaaatctgagaaactggggaggagacaatagtctcatatgtt aatagctgaggggacaaatgtgactagaagagatttctatctttcttggattgttcatcattcttgcagtacatgcaagt agctacataatggttttgttacatttttctttataggtggaagggatccccgaggaatagatgcacgagggatggaggcc cgagccatggaggcaagagggttagatgccagaggattagaggcccgtgcaatggaggcccgtgcgatggaagctcgtgc aatggaggcccgagcgatggaggcccgtgcaatggaagtccgagggatggaggccagaggcatggataccagaggcccag tgcctggccccagaggacctatacctagtggaatgcagggtcccagtccaattaacatgggggcggttgtcccccaggga tccagacaggtatgtgtaacactgacttctggcatccaagtgaaatcttgatctattcaggaattgattattgagcctaa ttattactgccttctgacttgggctgtttcttagcttgttagaaagggaagacttggatctccctgtagcttctctgtcc cttagggtggtgattttctggctatcaggattgtagttcaaaaaaaaacaaccttatcccacaataaatagctattcatt tggagcagagcccctgaaaatttaggggttagaaagtagtcttgattggggtacaaaccaacatcatgtacacggttttt tccaagatatacttgcccggatctcatccgaggtataactcagaatctcttattagtaggatctgagcatggatagtttg aaaaacttcccccaaatgattctaatgtgaaccctgactgggaaccactgggttagagtatatgaagagctgttagtggc catttagataatcttaggtttagagagacctgtgttaatttattgtcatcacatagcctaagtgaacagtggaatgtgaa aggcagtttattaataatcaccttaaaaggtgtggaaccgaagtcttgtctcctctcttttatttggatctctctgcctg tgtgtacatgctccctcttcatctcgacttggttgtggagaggtggtatgtgtgtttcttccgtgagtttttatatgctg gcaccttcatttccctctaactgctccaccttccttttccccccttcctctgcgtacttctctcttctttttttatgtgt cttcctccccatgtctgtgtgtatgagagagagaaagataatggcagagctggaatggaatacatcaatcatctaattcc ctcagtttatagatttggaaattaaggcccaagaattcaggtgacttgaccaaattcacatgactaaaaagtggcagagc aaggaacagaagccactactttttccactttactactctgtcctgttatctgcacatttgtgtgtgtgtatatgtgtgga tatgtgtctaccccctcctctgtaatatgaaatacaaatagagggtttttttgctatgtgtagaataaaactgttctcta ttgtgtttgaagtgtttgtgggccttgatttttattgtactctctatggtcagtagcctagtaacagaaatggttttt t gcattcattctgtcactcagcaaatatttattgagcacctactatgtaccaaacatagatctaggtacgggggatactgc agtgtgaacagaacaaagccccttcccccatgggcttacattctagttgggaagacagataacaaacaaataactacata atgcgcttacataattttactggtagttctatgatgcaagacattgcaagtaagggttggaagaacatttctggataata ttttgctcctttctctctgctggtacttgaacttattaccctaatactaggtttataccatttttattagtagattcgat aaagccaattagatctgaggcaagagaaaatacaaattttatcttcaaacctttaaaaaaattttaaattaatatattaa cttataaatatatatattcgttcatctataaaagatatatgtattaagaacttcaagccaggcatggtgacatgcacctg tagtgccagcactctggaggctggggcaggaagaccatttaagtctaggaacttgaggctgtggtgcattctgatcgcac ctgtgactagccactgcactccagcctgggcagcatattagactcccatctttaaaaaaaaaaaaaaagccagggtagaa tcctgtagtcccagctactctggaggctaaggcaggaggatcagtagagcccaggagttggaggcccgcctacacaagat agtgagaccacatcttaaactaaaaggaaccttgcttcctctcctatgcttgtctcccctgtggccctctaggtcctgta gataatcacttttattagatttttcatgttactttctggaaaacatgaatatatattatttttcccctttcactgttcta taccttttttttttttaacttaacaacatgtccttaattcatacttttaaattagattttaaaattaactctagtccact tagttagaaacttgtgggcaaaaggcttattattactagggtgattatataatttatcatctaaaggagaacatgaaaga aagtgctgttactttacttggaggcaaaaacataaactgggactatcttagggaaaccaagatgtatggtcacttttgct agtacttgtctgcctagaacaagcacacctagaaacttaaaatggccgttattgagtggttagatcacaattacagtacc tcagattaaagcttcaaaaagattatactcaattccgaattgtgctgctataaactcatgtgaccaaacaccacctgttc cccaataacctatggaaataaaaaattttaaaaaaaaagattatactcataggtgtttcagacccataatagctcgttaa tgttcagactggtctctggaaacttgtctctggtttcagtattgataatgaacagaacagtgataatattctagcagtct atacaaatctgtactaatgtttcatctatccattgtctttgggaaatgagttaatgcatgtaagtgaatgttccagataa tagaactattctaccaagttttttaacttttttaataaaaaattataaaaagtatttgatatttcctttcttgaacagga tacaaaaaaatagtttaatcagttttgactactcaaggtca cattgaatagattcattattgtctataccgtaatataa aacatagttatctcctgtttggtttctggtctccttcactgtcaggccgtcacctggctcttcatattactgaagtggta tctgctcctaacagttatttatccgtatttcttttatgttttgctgcttctaatctgctgggtaagcaggtaacaagttt gttaacaatatgtgtttattaagagagtacctaagctctgggtgaatgcctgagtgtgaacataatgcttgtatagggac attctaacagttagatttggtactcaagaggtcttttccttgggttctggtagtcttgcaaagggttgaactcattgaag atcttaagtaccagtaagtatgatatcactgtacttggttttttcactccagtcagtcatattttttggtctacatttag cagaaagcatctgccatatgttc (SEQ ID NO: 12061) ttcagttctagcgtcaacccggtgctctacgtcttcaccgctggagatctgctgccccgggcaggtccccgtttcctcac gcggctcttcgaaggctctggggaggcccgagggggcggccgctctagggaagggaccatggagctccgaactacccctc agctgaaagtggtggggcagggccgcggcaatggagacccggggggtgggatggagaaggacggtccggaatgggacctt tgacagcagaccctacaacctgctgcccttccctgtccctttccaccccccacccaccctccagaggtcctcccgacggc catgaacactacatcttctgcagcacccccctcactaggtgtagagttcatctctctgctggctatcatcctgctgtcag tggcgctggctgtggggcttcccggcaacagctttgtggtgtggagtatcctgaaaaggatgcagaagcgctctgtcact gccctgatggtgctgaacctggccctggccgacctggccgtattgctcactgctccctttttccttcacttcctggccca aggcacctggagttttggactggctggttgccgcctgtgtcactatgtctgcggagtcagcatgtacgccagcgtcctgc ttatcacggccatgagtctagaccgctcactggcggtggcccgcccctttgtgtcccagaagctacgcaccaaggcgatg gcccggcgggtgctggcaggcatctgggtgttgtcctttctgctggccacacccgtcctcgcgtaccgcacagtagtgcc ctggaaaacgaacatgagcctgtgcttcccgcggtaccccagcgaagggcaccgggccttccatctaatcttcgaggctg tcacgggcttcctgctgcccttcctggctgtggtggccagctactcggacatagggcgtcggctacaggcccggcgcttc cgccgcagccgccgcaccggccgcctggtggtgctcatcatcctgaccttcgccgccttctggctgccctaccacgtggt gaacctggctgaggcgggccgcgcgctggccggccaggccgccgggttagggctcgtggggaagcggctgagcctggccc gcaacgtgctcatcgcactcgccttcctgagcagcagcgtgaaccccgtgctgtacgcgtgcgccggcggcggcctgctg cgctcggcgggcgtgggcttcgtcgccaagctgctggagggcacgggttccgaggcgtccagcacgcgccgcgggggcag cctgggccagaccgctaggagcggccccgccgctctggagcccggcccttccgagagcctcactgcctccagccctctca agttaaacgaactgaactaggcctggtggaaggaggcgcactttcctcctggcagaatgctagctctgagccagttcagt acctggaggaggagcaggggcgtggagggcgtggagggcgtgggagcgtgggaggcgggagtggagtggaagaagaggga gagatggagcaaagtgagggccgagtgagagcgtgctccagcctggctcccacaggcagctttaaccattaaaactgaag tctgaaatttggtcaaaaaaaataaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa a (SEQ ID Nθ:12062) gatcaaaatttttacctattatgcatttgatatataaataagtatataaatgcacacacagacacagcaatgatggtgaa cagtcttcatacaattatatggatgaatctcataaaatgctgagttaaagaaatcagaccaaagaacatatactgaaaga ttctctctatatacaaagttcaaaaataggtggaccaattcatggtggtgttagaaatcagaagagaggctacctttgtg gggaggggacagtttaatgcccagaagcggtaaataaggaatcctctggggagtggtaatgatctggatgctggctacag gatgtgttggttgtaaaaatgcatttttttatatctagctttttccatgtgtatattatacttcaaagaagttcagttaa taatttctcatgtcactgtagagtagctcagttagccccagcaagcctctggcttaatcttgttttaccttaagccatca gtcatttacaagtaggaaaattcacagggaaagttagagtataaaatccagaatgaaggtttactgggtaagagtctctc cattttccaaagcccgtttatttcttgattccagttcttaagaagtctcagcattgtgtctttttcatgtatcttacaag aagacagcatgtgcttctaacacctgatacattgtatctaccagcacttggtaaacagaaaagaaccacatttttcttgt aggagaaatttggtgcctatttcctaccaggcaccaataagtgggaccaataggtgggattaaagatacagtagaaagta tttaaaacttgccagggggcaatagtctgaaaataagtaaattggtgctatagaatggaagttacaggcttctttctttt ttcccacaagatctgctccttgagcccctagagacttttctgtctgttactgtttcttcattcctcatctgcagagccag ccctgagaagtgcagaccaaagccagggaaggctctgcaaagatgtacaaatggaagtcaccttaataacctctgactgc tgcgcataatacatttcactcaaaagaggggttaaacaatggaacagaatacagaggccagaaataatgctgaacactga caaccatctgatctttgacaaaatccacaaaaacaagcaatggagaaaggactccctattccataatggtgctgggataa ctgtctagctatatacagaagattgaacctgggccccttccttacatcatatacaaaaaataactcaagatggagtaaag acttaaatctaaaaccaaacactataaaaaccctggaagatagcctgggaaataccattctggacataggacctggcaaa gacttcatgacaagacaccaaaagcaatagcaacaaaaaccaaattgactaatgaaactaatgaaactctttagttgtac aacagatagtttatctgtacaacaaaataaactatcaacagagtaaacaacctacagaatggaaaaattttttgcaaact atgcatctgacaaaggtctaatatccagaatctataaggaatttaaacaaatttacaagcaaaaaaatgacctcattaaa aagtgggcaaaggacatgaacagatgcttttcaaaataagacattcacacatccaacaaccatatgaaaagatgtttaac atcactaatcattagaggaatacaaatcaaaagcataataagataccatctaataccagtaggaatgactactattaaaa agtcagacaataacagatgctggtgaaggttgtggagaaaagggaatgtttatgcactgctagtgggaatgtaaactagt tcagccattgtggaagagagtgtggtgattcctcaaagaatgtaaaaccgaactgcctttcaatccagcaatcccattat tggatatacaccaaaaggaatagaaattgttttaccgtaaaggcgcatgcatgcatatgttcattacagcactatttacg atagcaaagacatggaatcgtctaaatgcccatcagtggtagactagctaaaaaaaaaaaaatgtggtacatatacatca cagaatagtatgcagccataaaaatgaacaagatcatcatgtcctttgcagcaacatggatgtagttggaggccattatc ctaagcaaattaatgcaggaacagaaagccaaataccacatgttctcatttataagtgacagctaaatattgagtacaca tggacacaaagaagggaacaatagacatgggacctacttgagaatagagggtgggaggagggtgaggatcaaaaagtacc cataggacactgtgcttattacctgggtgatgaaataatttgcacaccaaacccctgtgacacacaatttacctatatag aaaacctgtgcatgtacccctgaacctaaaagttaatggtgggggggtggggttaagctactttgtggtataaatctgag cattcatattaaaataaaatatttacctcattagagtaattaacatttattaagcaaagagccaagtaccttacacacat gatgtttaatctcacaatgatctttaatctcataacaaccgtccattgtatgtacatatgtggaaattgagccttggaga gattaaatgcatggggcatgccatttgactagaaactggaagcatcaggatttaaactcagttctgaatggttttgtagg ctttgttttttccacattatagcatggcctgccatgaagaacaggtcctttctggtgtttgtcttgtttggtttaagtga agcaaatatttatttaaatattcaagatatgctgttaaatttttactcaaaaatttgagtacagtatggatcttctgaag ccaaataactcttattcaatgcttagttgagaaattttatggagtagttctcaatttttatgtagttccactgcaaaggt aagtcttatggaaagattcactgtaattttttttcctcatttggacatcagctttttcttttcctcagacccgctgaaag ataatttttaaaataaaaaccttgtttttatatcaagtggggacattttttccaaatgaaaaccgtgtattcattttata tgataaaatcaatgttattatttttaaaattttgatttaaaaatcattaaaaataaattttcagatattacctgaaattc taccatccagagataatagtgcttaaagatttgatatatagacacacacacatatatacatatatatcatcctaaacttc tttgtataaatgtatataaagtttttaataaaaactaggagattaatgccctttgaatgaaaataaatacaatgtgtatg ctttaacatcttgcctttactttataacatttatcacagcagtcatgagataatgatttacatggtcattgttagtaagc taatagctaagtgcatgaactctggagctagcctccctggattttaatcccagatctgtcactgaccagctgagcaatac taggtaaattgctcttgttccttagtttcttcatctgtaaaatagagataaaaataatatccacctcataggattggtgt gagcattaaatgagcatacgtatgtaggccacttaacaacaatgccttcacatactgaacacaaatatacgagctgttgt cttattgggctcatgtttttcctaccactaagccgcatgcatgcaaggaccatgttggttttgttccacattgcatcccc aacctggtatacagtgtgcattcaatagttgttgactattattactagtggcatttaacaaatatctgttaaatgagtga agaaatacccatttactgcaagtgtgtctaatattgatggcataatgggggaaactcaaactctggagtcaaacaggttt taaaaccttattccctcatcctcagttattgacgttttttttttggcaggtgtgtgtgtgggacaacttattgaactttt ctgaatttccagcttcgcatatataaaatagagatagtgattcattcttgcaatgtatggatttgagacaattgtgtaag tttatcaataaatagtagctatttttgtataagtattacatataatatccaggccactgctttgcataacccaaaagggg caccattcatgcagaatacaacataaatggtgtccctggagcagtgcagtataggaaccctgaggggacctacagtatac tttatagttcatagattacaaattatccctttatcagagtctctcaaggttggatgtatttgaggtccataagagcaatt taggattaacagtagctgcagaaaccatctgcagtgatattctcattttaaatccgcgggaaagaagacagctataaact tgggacctgggtttaagcattttaaatgccaagttcaccattttctaaaacacaacaaatacccagtgagagagggagaa gggaagtaaatgcctctgaataagcaagttaatgtcagtagttgtactgtatgcatattgatgaacaatagaggaaccaa tgtccaatcagatgagcaggatatttggcaataacaagttgcctttgaggaaaaatgattttcttggcaagttctttatc agcattacaaagctaaaagctacgcttatcatcacttatactagcataccctgttgtgcaaatgctgtctgtgtttgcat ctgctattgttgatgcctggtgcatgaatcaggactccagcccacaagttttcccagaactttcttatggccatcatctt taagtgtctggtgaacagtcatagtttggtacacaaaagggtcaacctgggggatggctagggtttgactcagtcgttac atttcaatagagcaggaaggggaaatggtggcctgtaacctcagggaattttgccagttggtccaccccactctctctct cctgctctgaggaagtggcacagcctagaacagcaccacaggtgagagaaatgcaaaccctaaccagagaagcagactct ttgccagtagtaatagttcaggaccaccaccagcttttattaaaatttttaataacactcaagtattggcagaaagaaat aatcttgggttaactataactagaatattgactcttcctctgtggaagaatcagccaatcacatttgtttacatcagttc ccctgaagaagaaaaatacactgatgttgcagcaagacaaatttaagctagatgtaaataacttcctttagcctgtaatg ctaggctaattacatattggaactattttttcagggaagaattgtgtagggtttcagggaagaattctgaagaaaatata gagctgaaatgatcttgcagctcactgaaactgcagggtttagatccacactgatactcgttctattatcactgtaatga aggctgatggaataagtaaaaatgttttgtattagtatgtttttacacttatttgcaaggcataaataggttaggttttg atcttaatttaattctaacatgtattgtgcacaagctgtgagcagttttcaggagttaggtatctggccatgactgattt ttcaggagttaatcatctggtagaagggtcatacacaataggaagatgtgtgtgacaggttgtgatcattactataatca cacagagagctgtagaattttaggctggcagggtggctcacgcctgtaatcccagcactttgggaggccaaggcaggcgg atcaagaggtcaggagatggagaccatcctggctaacacggtgaaaccccgtctgtactaaaaatacaaaaaaaaaaaaa agccaggcgtggtggtgggcgcctgtagtcccagctacttgggaggctgaggcaggagaatggcgtgaacccgggaggtg gagcttgcagtgagccgagatcgcatcactgcaatccaacctgggcgacagagggagactcagtctcaaaaaaaaaaaaa aaaaaaagtcatgttagatccagaggggtagcaactggggctgggctgtcagtcaactcagtcaactcagtcaactctgc tcccccacaggagatgccagtgatgcattttcatggccaacattgtcagtcagcatcattgaattactcctgattataga gacacagctgcaaacgattccccattaaatatgatgtttcttgcaatgtttggaaggtactcctttttagtaagggaaat cccctcttctggcttgctgaaagttttttctttccattttaaaaatcgtgaattcctttttgcaatattgaggtggttat atggtttctcttctctaatctgttaatatggtgatttaatggttagaaattttctaatgtaaattccactcatattgcag aaataaacctaaactgagcatgaggctatattttttatttgcttctatatttggttgctatacagtattatgtttaagat ttgttcacatatatttgtgaatgggattggactatttttccttcttgccgatttttatctggtttttaaattaaggatat tttagacttatgaaatatttggcaaacaatccttggcaagtaattttttggggaatttgttttggctattttgagtatta cccaatatattttaattaagttattcttaatgttttcttaattaaaaaaattacctactctagagatattctttatgtac tccagattttgtctatttataccacttttcttttttcctcgatgagtgtcatagatgttcatctatttttttatcttctt tgatcttctcttattccttgtttctattaacttctgaagtttattattttcttttttccacttccttatggtttattctt tcaatttttctctaacttcttaagttgggtgtttaatttttagcttgctttgcttttttaggataagcattaaaactaca aattttccttgttattcttttgctgcaccccaaattgttgatatttctattgtctaatttctattcaattagaatacttt aaagtttctttttggtttttaaaaactaactttttaaattgacaaataaaaattgtgtatatttattgtgcacagcatat ggctttgaaatatatgtacattgtggaatggctaaatttagcttattaatgtatgcattatctcacatacttatcatttt ttgtggtgagagctatgtgacttttgaacttatgagttatttaaatatttttaaattattaagcatattgggattttaag taatttacctttttattattaacttataacaagtagaacagttaacctgtatgattctacatcattgaaatttattgaca tttgcttcatagtctattatatggtctacttttgttcatgttacatctgtagtagaattggctaatagttgagtaaagta cacatatgtctatgaaatcaagtgtaatccagagaaaaagagaaatttactgaatatattgttctaggtgctattatatg ttgtcatgtttaatcctcaccacaattgtatgaggcagccataattaattccactttacacatgaggagcctgagggtta aaaaaaaagctagctctactatttgtaaagaatgaagcaaagatacaaatgaaggcccacatatcctataactagatatt taagcattttaattcaagctttaaaactgctaaataaaatgtgctccaatttctatattgacagacataccttcctaatg agctggggttcgaatttagaaatctttgatgcttcagagtccacactgaaatgtggaggcacatagtgagttggtcccca gccttcagtccacccaccttctctt actaaatcacctttcacatacatgtatgaacaccccagcctccaagtccaaacc ctaaacaaaatgggacacccttgtgcatacacagagacacagcccatcctcaggaaaacctggaaaagtccatacaagtt ctggaagcaagcttgggacggtttcagtagtgtggtctataagggaggcctcagaagacaggttttcttaattctgtgaa cttctcccacagtagaaagggtgctggaggagggtcagagtgaggacttctaaagcatgggtcctgagtaggggccactc ttgcccaagtctaagaagggtactagaatagcacactactactagatactagaacccagatacaagcacaggtcttctga aattaataataataataactattaccattattataccagtagctgtcatttatttagtgcttattatttgccagtcactg ttctaaattctttacatgtattatacaactgccatataactgccatatgagggatgtaccctcattgtcaccattttacc gatgagaaaactggcataaaacgtttaagtaacttgtccaagttacagagcttagtgaagccacaatgttgctcaatttg ctctcaaacttcaaagggatgggaaggacacctaagtcatagagtctttaagaatcagagctagaaggaatcttagatgt tatctagtcagcctcctcccattacagtccaagagaagatggccctgagttacttgtagctatttttgcatgtgaattgc aagtgaatatacattctactgaagataaaagatatttaaagatatcgctggatataggaacagtggttttaaatctctag gctttaacttttctcagaacaagaaatcctttttggttttaatctatatgcacatctgtatttttctcaattatcgggta gtaaaatataacttttcttctgtaatattttttaactttaatgagtgttcctcataatagaaaagtttggaaaccattgc tatgggtatatactttctaaagggatagtaatttctctagaatattcatttaatgctccagaagtaattagcacaattgt gcaagtctgtgcatcatcaactatacattctgcctgtttactccaaatccacatgaaactgattatacagtcaaaggcga gcccagtggagaggcatttttggagacttcctggtacattgagacagggtcggccagtctgcgttagggtcttggtcaaa actgcatttctgaaactaaactcagattgctttcttttaaggggtcagaactgattcaaatctacatttttaaaagcctt agatgtggggcttttcctattcccagtctccgctattggtctttgtgaatccacaggcaatttggccacatccttgactc tctcttatattaagaattaaa'cagctaagttcatgcagaggaaatataacaaaggagggactttcctacaagatctttga aaaatggaacatttgcataagtcatatttagccagaactgttgttttatattttcctttctgaatactttgttacacctc ctcccagccaaccccccccctccctgaccccaactagtcagagaccaaagccttcacaatggtttacacttgaaccttcc tggccccaccctcatcatcacgcctgaataattacattcactgactggtctcccctgcttccgtttatctccactcctaa accctctgacaccttaatcttcccagaataccattgtgatcctgttccactcttgctcaagttttcccagaaactagagt acaaactttataagctttagagttgaaagccactctatctctttttcatccccaggtctctgccaaggcagtataacctg tccaacatctctaacttcaatacctttgtcttagatactagactctcctcctggtttctaattaaacctgatctaggatc taattttgcctctgaattctgttgccctttgccaagtgatctcttcctcctctgagccgcagcatctctgagcttgcaca cttagcatagccatagcacacacagccttagcttgcagttcagggtgtttaccttccctccccttccagatgctggatcc ccagggataggaactctgcccttatgtgtccatagcccctggtagtatgtcttgcagtcgtacattttcagcaaatgttt aattggttaattgaagacaactgtcccatgccttaagcctctctttttgctaaacatgcctgtgtcctttgtcattgaac aactattttgatctattttcttcctgacataggggtcagttccgaggatgctgaaatcaagagacatagcttattctctc aaaattgctttcaagagtgattttgttgtgaattgagaactggctgcctacttttggactacccacttcagcaagagtgt ttgaaaccaaatctattctaagtaattttttattcccttttctctatggcattagacacacagctcttttaaactacctt tcgttatctattaaacagacattcagtaactctatagacactgtctagctatatgaacttagacaaactaatatctctga gcttcagtttcttaaaatttaaaatgaggacaataccatctatggccggggattaaatgctatgaggaatgtaaaccaga tgtcaggtaccatctctctaaaatccagataaaatgaattaaaaatactggccgcaaaccctctctaagagttctcaaaa ttctcagagagcttaattttcatgctcaccatagcaccgattttcttctaaatattttgtttctaccaaaatattttgtc ccaattttgccttttatggctatttcttcatatccactttcccaaactaaagaagcagccccttcaccttaaactcctcc ttcaaagcaacctaaatacaggtctgggtttgtattcctagtgggatgttacagaggttagtgtgatgcagaggaggagt catgctgtttaaatccatactagtccccagaggccaggctgcttctgccacccctacccctcccgccacagagctcttca gcttctcacatttctagttcttctctctctactttcattaccttctctctttttttttttcttctcatgtgctcacggga gcagagaaaattaactcctctaagttttcttaacacagagtgccttaattacatattactattgtttgagttcctgccaa cactacgtctgtagggtcacacctgctatattagaggcttatcaaaaaaagatagctttctcctaaaaagggatttggat gcctactaagataactggatgccaagataagtttaacctaacaaactttattattattattattattattattagagata ggtacttattctgtcacccagactgcagtgcagggatgcaataatagctcactgcagcctcaaagtcctgagttcatgca atccttctgcttcagctccctgagtagctaggactacaggcatatgctactctgcccagctacttttaaaaaaataatta gggatggggtcttgttgtattgcccaggctcgtctcaaacttctggtttcaagcaatcctcctgccttttacctccctaa ttgttggagttacaggcatgagccacagcactcaaccaagatttaaaaacttttaaaagaaatcacattacttactgtta tcatcattatggttactaccagtgttaaaacaattggtattgaaaacaccactaccagatcaagcttcaaaccaagatgt caagtaaatattattgtcagacctctgagcccaagcctgcaggtatacacccagatggcctgaagcaagtgaagaatcac aaaagaactgaaaatggccggttcctgccttaactgatgacattccaccattgtgatttgttcctgccccaccttgactg agggattaaccttgtgaaattccttcccctggctcagaagctccccgactgagtaccttgtgacccccacccctgcccac aagtgaaaaaccccctttgactgtaattttccactacccacccaaatcctataaaacagcctcacccctatctcccttcg ctgactctcttttcagactcaacctgcctgcacctaggtgattcaaaagctttattgctcacacaaagcctgtttggtgg tctcttcacacagaccatgtgacatttggtgccgtaactcagatcggggaacctcccttgggagatcagtcccctgtcat cctgctctttgctccatgagaaagatccacctatgacctctggtcctcagaccaaccagcccaaggaacatctcaccaat tttaaattgggtaagtggcctctttttactctcttctccagcctctctcactatccctcaacatctttctcctttcaatc ttggcaccacgcttcaatctctcccttcccttaatttcagttcctttctttttctggtagagacagaggaaacgtgttct atctgtgaacccaaaactccagcactggtcatggacttggaaagacagtcttcccttgatgtttaatcactgcagggatg cctgcctgattattcacccacatttcagagctgtctgatcactgcagggacgcctgcctggatccttcaccttagtggca agtaccactttgcctgggtggcaagcaccacctctcctggggggcaagcaccacctctcctggggggcaagtacccccca accccttctctccatgtctccaccctctcttctctgggcttgcctccttcactatgggccaccttccaccctccattcct cccttttctcccttagcctgtgttctcaagaacttaaaacctcttcaactcacgtctgacctaaaacctaaatgccttac tttcttctgcaataccgcttgaccccaatacaaactcaacaatggttccaaatagcctgaaaacggcactttcaatttct ccatcccacaagatctaaataattcttgtcgtaaaatggacaaatggtctgaggtgcctgacatctgggcattcttttac acgtcggtccctccctagtctctgttcccaatgcaactca cccaaatcctccttctttccctcctgcctgtcccctcag tcccaaccccaagtgtcgctgagtctttccaatcttccttttctactgacccatctgacctctcccctcttccccagact gctcctcctcaggtcgctccccgccaggctgaatcaggctccaattcttcctcagcgtccgctcctccaccctataatcc ttctatcacctcccctcctcacacctggtccagcttacagtttcattctgtgactagccctcccccacctgcccaacaat ttcctcttaaagaggtggctggagctaaaggcatagtcaaggttaatgctcctttttctttatccaacctctcccatctc agttagtatttaggctttttttcatcaaatatgaatacctagcccactccatggctcatttggcagcaactcctagacat tttacagccttggacccagaggggccagaaggtcatcttattctcaatatgcattttattacccaatccactcccaacat tagaaaaagctccaaaagttagactccggccctcaaaccccacaacaggacttaattaaccttgccttcaaagcgtacaa taatagagtagaggcagccaagtagcaacatatttctgagttgcaattccttgcctccactgtgagagaaaccccagcca catctccagtacacaagaacttcaaaatgcctaagccacagtggtcaagcattcctacaggacctcctccatcaggatct tgcttcaagtgccagaaatctggccactgggccaaggaatgccctcagcctgggattcctcctaagccatgttccatctg tgtgggaccccactggaaatcggactgtccaacttgcccagcacccactcccagagcccctggaactctggcccaaggct ctctgactgactccttcccagatcttcttggcttagtggctgaagactgatgctgcctgatcgcctcagaagcctcctgg accatcacagatgcttttggtaactcttacagtggagggtaagtccgtccccttcttaatcaatgcagaggctacccact ccacattaccttctcttcaaggtcctgtttcccttgtcttcataaatgttgtgggtattgatggccaggcttctaaaccc cttaaaactccccaactctggtgccgatttaaacaacattcttttatacacttctttttagttatccccacctgcccagt tcccttattaggctgagacattttaaccaaattatttgcttccctgactattcctggactacagccacatctcattgctg cccttcttcccaacccaaaagtggcaactcctttgccacttcctctcatatccccctaccttaacccacaggtatgggac acctct ctccctccctggcaacaaatcacaccctcattactatcccattaaaacctaatcacccttacctgggtcaacg ccagtatcccatcccacaacaggctttaaagggattaaagcctgttatcacttgcctgttacaacatgtccttttaaagc ctgtaaactctccttacaattcccccattttacctgtccaaaaactggacatgccttacaggttagttcaggatctgtgc cttatcaaccaaattgtcttgcctatccacgccatggtgccaaacccatatactctcctatcctcaatacctccctccaa aacccctccataacccttattctgttctggatctcaaaacatgctttctttactattcatttgcacccttcatcccagcc tctcttcactttcacttggactgaccctgacacccatcagcctcagcaacttacctgggctgtactgccgcaaggcttca tggacagcccccattacctcagtcaacccaaatttcttcttcatccattacctatccaggcatagttcttcatgaaaaca cacgtgctctccctgctgatcatgtccagctaatctccccaaccccaggactggcaaattgactttactcacatgcccca aatcaggacactaaagtacctcttggtctgggtagacactttcactggataggtagatgcctttcccacagggcctaaga aggccaccgtggtcatttcttcccttctgtcagacataattccttggtttggccttcccacctctatacagtctgataat ggacaagcctttactagtcaaagcacgcaagcagtttctcaggctcttggtattcagtgaaaccttcataccccttaccg tcctcaatccttaggaaaggtagaactgattaatggtcttttaaaaacacacctcaccaagctcagcctccaacttaaaa aggactggacagtacttttaccacttgccattctcagaattcgggcctgtcctcgaaatgctacaaggtacagcccattt aagattctgtatggacgctcctttttattaggccccagtctcattccagacaccagcccaacttgaactgtgccccaaaa acttgtcatccctacaatcttctgtctagtcatactcctattcaccattctcaactacttgtaaatgccctgcccttttt tacagtgctgatttatacttttcctccaaaccatcataactgatatctcctggttttacctcaaaccgccacccttaagt ctctcttaaagtggatagaagatcttcagtgacaaggtacactccaatactttcaccctaataaagccctattctttact tttatattcactcttattcttgttcccattcttatgccactctctacctctccccagctatctccaccacactatcaatc tcactcactctctcctagccatttctaatccttctttaacaaacaattgctggctttacaatttctctttcctccaaaat caccgagtcctcaatttactcactgctaaaaaaggggactctgcatatttttaaatgaagagtgttgtttttacctaaat caatctggcctggtatatgacaacataaaaaaaactcaaggatagagccaaaaaccttgccaaccaagcaagtaattatg ctgaacccccttgggcactctaattagatgtcctgggttctcccgattcttaatcctttaatacctgtttttctccttct cttatgcagaccttgtgtcttccatttagtttctcaattcatacaaaaccgtatccaggccatcaccaatcattctatac gacaaatgttttaagggaggagaccacccctcatattgtcttatgcccaatttctgcctccaaagaaagaagtaaaaatg aaaaggcagaaatgaaatccacaggcagacagcctgatgccacaccctgggcctggtggttaagatcaacccctgaccta a cagttatgttatctatagattacagacattgtatggaaaagcactgtgaaaatccctgtcttgttctgttcctctaat taccagtacacgcagcccctagtcatgtaccccctgcttgctccccctgcttgctcaatcagtcatgaccctctcacgca gacccccttagagttgtaagcccttaagaggaaaaggaattgttcactcggagagctcggtttttgagacatgagtcttg ccaatgctcccagctgaataaagcccttccttctttaactcagtgtctgaggggttttgtctgtgtcttgtcctgctaca gttteatctaacaaccccataatatcaccccttaccacaaaatcttccttcagcttaatctctcccactctaggttctca cgccacccctaatcctgctcgaagcagccctgagaaacatcgcccgttatctctccacaccacccccaaaaattttcact gccccaacactttaccactatttcgttttatttttcttattaatataagaagatagaaatgtcaggcctctgagcccaag cctgcacgtatacatccacatggcctgaagcaagtgaagaatcacaaaagaagtgaaaatggctggttcctgccttaact gatgatattccaccattgtgatttgttcctgcgccaccttgactgagggattaaccttgtgaaattccttcccctggctc agaagctcccccactgagcaccttgtgacccccacccctacccacaagtgaaaaaccccctttgactgtaattttccact acccacccaaatcctataaaacagccccaccccatctccctttgctgactctatttttggactcagcccacctgcaccca ggtgattcaaaagcttcattgctcacacaaagcctgtttggtggtctcttcacaccgacacgcgtgataattattatatt acttttaactaaaaccctttcagagtctcgcagggaaggctgtatatatctcataaaatgttggggcccactggatcaga caaggccacaaaggccaaagggaagtaaagatctcattatttctcctaataatttccctgtcctttgtcataaatggtgg gtaggctgttatggtgatggcagattttctttccataaaatgtccataataggacatttgaacagaagggaaaaatcaaa ttgctgaagttgaaagagggcaatgcaaagaactttggagaaagaactgtacagagaagtcaactggcagatgggaggaa gtttaaggggaaaaatatagatgtctaaagaatacatttattcattttccacagtgcaatttggacaagaagcctctttc ttgcttctttctattctcattaaatcattagagctcaagcaatccttctgcctcagcttcccgactagctaggactacag gtatgtgctactatgcccagctaattttttaaaaattagattttaatttggtgaactatttctgtaggaaactacaataa tacagcccaggcacattgatcttgggtgaacaaatcagaaggaatgaataattctgtgttcctgggactctgacaatttc atgaacttggtactctgagtaaagcataggaggagttatttcataaaatgtggagcacaatcatgtgacaaagataatgg gatccccatttcataaataaatctgaagttcagagagagtaacaactggccagggtcacatcacggagacagaggcaggg ttcccactgatgcctctgactccctgtcccaggcccttcctcctcccgcaagcagaagtgcagggggcagagctgaccct gtgcagtgaaaatctgagggctgagttcctattggaacacaagtgaaagacttcctggcttctaatctcaggataaggac tcagagctccatctgttccagccttaggataagaaccagaatcttacaccatgaaagcatgaaaggtaagatttgagtga ggaaaaaaaaaaaaaaagtctgtgtttcagattcagttcacaaagcagtttcatacttaaggtaccatcacaataaccct gtggggtaagcaaggcaaatttcattcttgttttatgggcataggaagtaagtctcagggaggttaagaccaaggtttct ggagaattttatattatgaatcttgatttatgggattactattatgtaattcetaagatcatataggaatcctagagctt gaatatagaactttatttttaaatctatatacatcataattacaaggagtagtgtccatttgggttccttggccctgatg tgttagtggaataaacatttttgtcagggttgccatgtgtgtctgtgcacgtgtgcactgtacacctccaggggatgtac cctaaaccacatgaatgtgatttgcacatccaagatttacagtgtactatagggagaatcttttgcaacagcttttgcta taatacagaatctgagatgtctttgagaaagaaaagtgtaatcattaccaaaaaattattctcataatgtgtgcaaattt gtatgaaatctatattggccatgggacaaggaggtatttccagctagcttctgaaagggctctattctctcataagaatt cagctgttgacattaggtgatatctgcccaggtcatcagatgccatagagaaagagggtttgctgaaacttatatcagca gtgcactgtatgctctttctgatttatttgaacattcatttattgagtgtcaagtaatgcactagatactccagggatct gacacaaactctgccctgaaggagcatgtaatctcactggggagaaaacaaaacatatgataatttcaaaataacaaact aggcaaactagttaacacttaaaaagcaggctttattcaaatgcaaaattgcatgttacagggtaacctttcagtaagaa gccaggaagaggagctcatcatgggttggattagtaaaggactagttataaaagaagtggtggggttgagggaggcctga gatgaaatttaaagaatatgtagaatctaggtaagtggataaaaggtctgggggcaggggaaaggagagcatttcattgt gaatcaaggaatttctccacctgttttaactcttccatatgacatcaaagagatgtcacttgcagctagcatttcagtga tgttttcttactaataatatcgtgataaaagaaacattgactataagaaataggaatgggtctcataaaaggaaacagea aaacccccaaactaaaaaacagcgcaggctatttctetcttctctccttttgcttggcactcatgagatgctaggtgtgg aagtcagccaactgaaaaagagaggtggctgaagaaggtggggaggctgaagccagttaaataggatggtccaattcaca gacggcgaggctacagtgcaaataggactctttcaacttgagcaggaccccattacttcactggagttagaaagaaagga gagcgtagactttttgaactttctataagagtgtacctccacagtatacagaagacgacgtgaaatttgatctgcaagaa aactgagtccatattcacatatgtatcaaatttgcacttcatttagaagtgtctgtcatcaagtacagcactgaattgaa actgaaaacaagagtcaagaaagagcaaagtcagccatctttatattccacatgaatcctttccctttatggtcttattt gtttctcctcagaaaagacaaaaagctgagctgtataaacacctgtgggctgggggttgagggataaatgaggggcgaaa tggaagctgaaggaactgttggtcaggtagaaatcttcccagatgcactgaaggaaacacacttcatgtttgacgtagga ggtgccaccacacaaaacgtttcatggaaggatttaaaggatctcatgatttttagtattccaagaattttctttcaeca agggcgatttaatatgggtcattcatactgaaagaaaaacaaaagataataagagtttaaaaattgcaaaacttggagtg ttagtagtaaaggtaaatattca tagagatgagaagaggagcaaggaaatgctttcagctggaaatctcagacaagagg ccaggctttaggaacctctgaagatgaaeaaatgtaagcaaaccctagtagcagcacttctcagattttcatgtgcttac cactcagagatggtgttaaaatgcagactctgattcagtaggtctgagtggagcctgagattctgcacccctaacaagct ctttagtgatgcttatgccactggcgcacagaccccacttggagaaatttttgtggtgcatacggtctttgtctccagat ctaatgagtctgaaggacagtgtagattgattttttaaatttatgtttattttaatttaatttaatttaatttatttatt tatttatttttgagatggagtctcactctgttgeccagtccggagtgcagtggcacggaggcagctcatgcaaccacggc ctcctgggttcaagcgattcttccgcctcaacttcctgagtagctgggaatacaggcacgtgccagcacacccagctaat ttttgtatttttagtagagatggggtttcaccacattggccaagctaatcteaaactcctgacctcatgatccacctgcc acggcetccgaaagtgctgggattacaggcgtgagccaccgagcccagctgtagattgattttgagcagtggaaagtcaa ggaattagaaggcatgcttaaatggaaagtgaaattggagaaaatttaaactcatgaaatagtggtggttataaactcgt gataaattatatcctgggatataatttaatgagatggtaacacatttagtttaaagaaataagtgacactttttttgtgt gacacaactgtettattcttggaaaggacaaggagagaatgaaatatggtatgtcttcacageacctttcaaagggagaa ccagattctgaggagctggtctcatgatgaactgtcagggtaaaccacagttcagcagctgcaaatgtgcttgccaaaat agagacaaaaaaatgtttctgaaaacaaaattteacatatgccctcctctgaggttggcatcatatcttcctgtgtatct tgggtgtagcttctatcctgccagaatttagacagtagaaaccaaatgaggtgataaacagagtcattttgcagaagagt caaaataacccagcaagaaatgaaaccacaaatgcccaaggagtcatteattcaceattcaaaagctaatagaaatgaac acaaactactatgaaaattcacccaagaacttaaaaaaaaaaaaaaaggctcatggtgtttagtgtgatag attcattt tacctttgacttgttctaaaaacacaccatacttctaccccacccttcctcagtgccgtcacacaatggtttcagtgtga aaaaaaaaaccacgttactggaaaaggagggtgcctgggacttgccactctaagctggtagtcaagggtcttgagttcta aaagcatacgcgttaagagcatgattcctggatccaaatgagtatggatctcagcattgccatttattgtgacctcaggc tattttatttctctgtgcctgtttctttatcagtaatgaagatgttcatagacccttctcccacagacttaaaggcatat ttcatgatttaagacatgtaaaccattcataacagtatacaacatggaattaatatttgataaaggtttatgattattgt aactaactctgtcacttgctcaaggcctatagaaaacttacttaattagttcaactacaaaaagagtttgaatgtgatat ccaccaagatcatattcagacctagaattctgtgattcttatgaattaatacagccttggtcaataaatgagagctgggc aaataattcttctttgctaggcctttctagaccatctggtgaagcattcaagacttatgttattggggccagccttcctt tccaacttcaactccacaactcctcaataagccatgggctcaagaaagttctgctcagtggcccctgaaaaatgctttca tagtctcactaccataccactgcttacacaatttccttcctacagactgccttcctttcctgcttttctccatataccta aatcctatctattcttcataagcaaccttctttataacattttctataaccaccaagccaaatgaccttttccttcttaa atatagcacccattggccattaccatgctctgccttgtatttttctgatttttttctttctatattcctgtcttaactcc ccagctaggtaataattttcctgaaatcagggaccaggctgactcctcttgctgtctcaagaaagcttagcagtttccaa cacaaaaatgttcaataaacaactattaattgactgattataaaaaatcagtgaaccattaaacttaatatagcaatttg cttagcatggtaattagctttttgctaatattcttccagccagtctctcctcctgtgcctcaaggacatcttaaaaaaaa aaaatctagttgatctgcttccatctagtggcaattaaaacaggtggttccggtagccagaaaacagctctgggtagatt gtgccagaaaatactttcactcagtaggtgcgagtttgaaagaaatcttcacatctgtgggtttcctgccacagacatag ggagaccagcccagagaaagaagcctttcctcactagactccatttgcactagtaaagagaagacagagtaattaaaaag aataaaaagaacctccactgatcgtacatcctcatccagttacccctgccccacttctccttcacagccaaacattttaa aagagatgactgcttgttctgtctctactttctcatcctcagtaatgctcaatgcttggccgtctgacctctgtcttgat 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gttttcacattttagaccctgccatgccatttagtaaacagtacaactttcatgtcttattcc catctgtcaaatttaa gccattattgctaccttgctctagagacttcaaggaagaatggactcaaggaatcagaagaatttttgtatttggaaact atatgagatgagattagggagaaacatgggaactaagagaaaatgttatcttttttcattgatttaaagagtatctatta ta atcaagcattactctggggcttgaagagcttagatttcaccctgtaggacaaaatggtaggtagaaattaatgggtg gattgtcatgtatgtgtgatgtgttttaattgcttttaattgatcagtctccctgtagtatgaataatgtatttgagggg agctaatttaaaattgtggaactcatctaataaactattgcaagaatctagaagaaagataatgacggcaatggtagtag agttgacaagtggaagacaaattagaaaaacactaagttgtaaaaattggtagaatgttaccctgcataaatgttggggg agttaagagagtctcataccagggtgcccatgtaaatggtgattccacatactgagataagaaatacgaagagaaaagct gactgggaacaattggttttatagtcttttaaacatcccaaaggacatccttagcatatttgagttcagagctggagata ggcttatcagtccaaagatcacatagatttgtgagtccgcaaaagtcagtaagtttgaccaaaggatacatgtagattag agtcagaagagcaatatacaaaagacaaaagctgagaaattatagtagtttatggtcctggataagtgctcatgaaggat ctcaggagaaatgatcacaggtagaaagaatgagaaaagagtgatatgagagaaaccaagacaaagaaaagtaaaatgtt 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aaaaacaactgtagtaaaaacactcagaactttattctggttaacatcatgccttgctaggggacaatagtttccctttt tgaaataaatttaaaacagatgtaacataatttgttaataaacaatgagggggtaatctagaataagtaacttttaccat atcatagttgacagcatttacaagttttttaagtccctaccacacttgtattgaatgaagaagtatggaagattataata tattcaatgcaagtaaaaatatcacaatccttaagaactctttaagaagcactgaatcccatagggatgaaagtgattaa attgtgcatagtaaccctcgcacagagcattcagtaggatttgcaccattaacaaccctccatgcatttgcctgtgggca ttcaacatctgtcatttttttaagttataatatttttagtcatttttttcctctaaactctggataattattattcattc ttatgacagcaactgtgtaatcagctgtcgaaacactgtgaagggcaaaagaaagaaagccacaaaatattgtgtttctg tgccaagattttacagcgagcaagggagagttagaaaaggaattctgagatttcagagtcttggtctcttcacctttgct tggaagaaaatatcctttcccttcattagccaacactttcttgatcctgagagtaggaaagggaacactgagtcttttca gttgaaggccgtccttgcctgctggactttgatctattgaagtggtgatgggtgttgcggtttcagccataaaggcatct ggcatagtaggcaagaagggccagagacccgaggagagttatctgtctctgttaacttcagtgtatccctctagttcccc agatgcacctgtttctgtaaatataaacatgcatgtcatcagaacacttaatattctgcatactgatcatgacaacaaaa tgtaccttctaacacagacactctcactaggatagaccatgtaggaacatcgaattctattcagttaggacagtgatgat gtctacatattatacctctgtcaaaacctacagaatatacaacacagcacagagtgaattctaatgtagcctgtggacat taatgaataataatgtatcaatattggcccatcagttgtaacactaatataagatgttaataacagggggaattgaaggg gtggtggggagatatgttggaactctttgtgctttctgctcaatttttctgtaaacttaaaaccgcacacacaaaaaaag ttattttaattttttaaaaagtattcagagggacttgacctttccaaattctctcaaagcaggtcggagtagttaagaac acaaattttagaaccagactgccagagtttgaatcctggctacaccacttactagctttgagatttcagacaatttactt aacttctctgtctcat ttcttcatctgtgtgataagaaataaagtaacaggccaggcccagtggctcacgcctgtaatc ccagcactttgagaggccaaggcgggtggatcaggagttcaagatcagcctggccaacatgacgaaaaaatacaaaatct ctactaaaaatacaaaaattagctgggtgtggtggcaggcacctgtaatcccagctactcaggaggctgaggcaggagaa ttgcttgaacgcaggaggtggaggttgcagtgagccaagatcatgccactgcactccagtctaggcaacagaatgagact ccatctcaaaattaaaaaaaaaaaaagtaaaaagaaaagataagaaatatagtaccagcccctatctcagagttcctagc ttagaaaaattcccagaatataataagtgcaatgtaagggtcagctatcttcattattatta ctatcataaatgaaatt acacaataaagctagatccgtttctttcctctccttctacaaaaaataaagcaactttccagaacaatacccaggtgatg atttctcccctgctccctccctaagatattggcaagtttggagggttcaaggagaaacagagcatgtagagaagatacct ctctcataaccatttgtgatttacaagtcttacctgattcttttgaacttaaaggatgtaagaaggcttttggtagcttc catctgattcaaggctttggcagctgctgtggaatacatgagaacactaggtaaagcactgtcttccaacatgaagagag aaaaatatgtggaatgttcaatggcatgctttgtataagaatgcaacttacctggcaggaacaaatttctttgctgcaaa agaaaagacaaacaaccattaattcagactaaatgacttttaaggatatattaaatccagatacaatatgacttaattca tcaagtgttgcaaactcgatgcttcagggcctctgtaataatcagagcacaagcatggctctgtggcatctagggtaaaa tgcaaagtgcacagccatccaaagggcatagcagcttcctaatgccagcaaatagctacggggtcatcttgcccaattca gctcccaatttttcatgagaagtccaaagtcttaatttaaatgtgagatttcctattttgtaaacgtcagaacttaactc aaaaatgttttaagtactcttaaacatgtaagccaaacaaaccatgagtgtagtcagatgtgcttccatattccttatga gagactctcaaatttaagcctgtactccaaataaatctccttaggaagaattttatccattttccttagagtgctcatca tggcagttccattgcacaattccgggaggcatcatataattcaacatgaatagcaccccctggagttgtacaatattagg cacgactaacatttttatttcctgaaacacttcccacactgagttgtactactaactcttttcttaatacttctgcttaa ttatactgcattttatccagattctaattattgtttaaatcagtaagcaagaccatgacttatcaatgagaaagaaatgt attttcaaaaacatttttgaagtacattcataaacttcctcacctttccgtaagcatttccgaagccagaggagaaatgg tgctaatgtcaggagggagagtccagcagcagaaagtccagctaccaagggaatgttggactcagtgggagctaaggaag taagagacgaagaaaggtcatgaggaagaattgatgttaaagtctctccgtcctgtccctttggccttttttctgtacat tcattactaggagcagaagagctatctagtttaatacaagaagcagagatgtggcattacaggcctttgagatctgctcc aagccacctttgaagctatttccaccattggcaggcagaactctaacttgccaagctcgttcacaataccacaccacacc ttggttaataaacactgcacttgcttgctctcttgctctcactccctcttgttttccatttcccctttctcctctcctct ctctgtctcctttttccagttgtcagaattctaccctttccatcaacatgcaacttctgttttttctctatccccataca acttaatattcacaacttgtcaacctgggcgaactttctggtttggatataatgaatagttgattactgtaacaagatag ctccccctttttctttttaatcaccagacaaccaccatcaatcaatgcatcaccttcacaggtaggtagcaggccagacc agtgtcctgtggctccacatgtccgagctgcagagccattgagcgtccatccttcaggacaggcgaacttgcacacagtg ccaaacacgggctccccactgcagctcatgttgatctttcccggaactgccaggcttgaacattttaccactgcaaatgt taggtacacaggcagagtttcagaaaaatctactggaaaacttccaaaacttgcttaaaagtcaacaatgaatgtaaagt gtaagcgctacttagttttcagcatgtaggaaattaggaccaaacccctttggggcaatctaggttcagaaactttatga agtatttgacctgtaccctaaaaaagtctgcactcaattctaccttggcaggaaggaacctcttctgtccattgtccctg agatgtgcactcaagttgagttgatccatgtaattcaaatccctcctcacagctgaaggcacaagaggacttgtaggtga attctccaataggggaatgagcacacctcaccaaacccttcgggggctggtggacagcatcgcatctcacagctggaaca cacgagagagcactttagaagtttgtttgcatctccagcaatacgtttcccaaggtaaccaagttcccaagctcttcaat agttctttttatcttaaaataaaataaaaacaaagactgtaccttcacatgtgggcttctcgttgtcccactcccctgtg gggccacattggagccttttggatcccttcaacacaaaaccctgctcacaggagaactcacagctggacccataacggaa actgccagaagcactaggaagacaattcatgtagcctcgctcggggttggacaaggctgtgcactggaaagctgagacat caaaatgatggtcagaaaatattgcagtggaactagagagtacttggcgtttgttgagtgaacccagttcattcaagcaa cacttggagaactgaagattctttataattccctggacaaatgggaagatggctgtgttttctttgaatttcagccccct cactgatcatggcactaattaaaagactaattaatcagaacattagttcctgagcactgttcttctaacacacaaaataa attatggtccaaggaaagatttcacgcagtctgaggacaacatatgggtcatggatgtttatagatggtgccaaaaagaa agaaaagaaagcacccctataaaatttgtctgttttgcagtttggtttttgtgttatgttttgctactggaaatcattct gtgctggctttggctaggacaaggccagtgcctgatagtaaaaactgcttgttttcaatatccttgctctcactttaaag tgaattaaaatttactgcttatatatgcatcaatactatctctgtagctgacaccatgcttgaaacagtctcatcactgc taattatgagccatttcagaagacaggtgtgatgagagttttacattcaaatcatgttctcattattctgctttccgaat tttctaatatgattcctttagattaagaattctgtctattccatgctaatgtctacaaagttttatcagcacatcacagt taaaaaaaaacagcaaagaattcattcttaacacatatgatcctttccctggccaaacattagttcttttaaatgaatct caaagatacgagggttgctcatcaaatctgatttctatagttaaagtgggtattggttttttttttcactgtccaagttt gaagatggttgttctttaagaaagtataaatcgaaggatctcaagcttaccttcacaaactgggatttgctgtgtccact gcccttgagtggtgcattcaacctgggctggtccctgcaacatgaagccttcctcacaggtgaagttgcaggatgatttg aaggtgaactctccagcaggggaatggctgcacctcacagagccattctgaggctggcggacggccctgcatgtcacagc tgtaacaaatatacgcattgatattagcacggcctagaattagcttgcccatttccagtatgggttgagagaaagaatgt tcacagtaagtctccatgtggaacaactctacctttacacgttggcttctcgttgtcccaattcccagatgaggtacact gaaggctctgggctcccattagttcaaatccttcttcacagtcaaatgtacaggttgtgttccatgggaagcttccaggg ttttggaaacattccacgaacccattggctggatttgtcacagcatcacactcaaccactgaggattttaaagagcacca tgaattttacagaagaatgatcttttcacttcctattgagctgggtgcctaacagagtgaggaagctgccttcaaagggt agatcccaaagtcctatgtcaattcttagggacatgcacagccagaataaaagcttttattctttttcatggatattcta tcttttctgatttccactttgcctatgctgagtggtctctaatctatgttatcatttacgtgaggtaaaaatttaaaaaa aatagattccagattaggagttatgactagtactgacatacgtaggctattcatttattttagcccatcagagcctgaag aactgatttttctttttttggcctctggttcagaaagataaaattaagagagaaaaagagatactaagactgcttgacta tcatggtcttaagttagtcccatggcttggaaaagttaaacagggaaacaagatgagaaatccattgagatttctagagc tttattgttttatggtctcccttacaaatcaccagagcctcagaaacacccatttcaagcatagaataaaaaaacctctc tcaacccaagcaggtactgggttggcaatatacattggctgagagaacaaattgtattaaaaacaaaaacaaaaaaaaaa ctttccctgaagttttgaaaatgtaagttgaatcaaaaaacagaagcaatgagggatgagttacagaacgttctgtgcat tctcagagggatttaccattgcaggctggaataggagcactccattctccagaggacatacactgcatggtctccatgct gcttggcaggtaacccctatcacagctgatagagcaggaagaattgtagctgaagtttcccagtgggtgactgcaaacca ggcttccatgctcaggggattccagggctgtacagttcacaactgaaaaagaaacccaaatcagttctgctcatctctca cctttaacagataagaacactggaaactagaactacagtttggttttttttttttttagtttaaaaatttataaaatttc taatggaatttgtaaaattgactgtaattctaccccttttcttttattcaagaaaatgctgatccataacaacaacaaca aaaaagcagtgatgacaaccataaaaaagaaatattgagtgatatggggagagtagtgtaattgtgtttacctcaaaact gttcaaattatatgaacaaacacagcaaacttaggtaccacaacaaatttcttgttacttttctcacaactgctaaaaat actacagtaagcttccaaccaggatgagaaccattcacaaagctatatttcaaatttaagtactagaatacattacaaat tttaaaaccctaatgctgcactgtctactatagtagccactatctgtgtggctactcaaatttaaacttgaattcgttga aatcaaataacatttaaaattcagttcctcagtgtcaccagccacatttcaagtactcaataaccacatgtggctcatag gtacacactggaaaacacagctatggaacatttccattatcacaaaagctctactgcacaacgctgtgctaaggaatctt ggagagaagctcatctaactctcttaatgtacaaatttaggaactgagacctcatttcattcaagtgacttgctccatgc tacacggctagtcattacagagccagaggccagagcatgaaccaagataccctggactctgtaactcactcatttctact gcaacgtcttgttaccacctagatgaggtgagtacatgttcctcgcagggacacagaattacagtttattgaatgtgtcc tgtgtgccaggcaccatgtaaccatgagcctatgaagttcacactattattatcctcattttacaatgagaaaactgaca tagagagttaaactatcttgtcaaggtgccaaaataaataactggtgaatctaggactcaaacccagcagggtctgactt catagtctcagctcacgatcaccatatgacaccatctgcaccagggaagggaaggcatgcagacctgactctaatgccag ctaggacgtgagatggtgctaccatctcaagtgaagaaagaggcaagaaccagacttactttgctcacacttgagtccac tgaagccagggtcacacttgcaagtgtaattattgatggtctctacacattcaccgtggccactgcaggatgtattggta caggcagctacggaaaatacaaagcatgatgaggaggactattactgtgcttatactgagtgcctttgattttagaatca acagtgtgcaacagagacatcagcagtcctacagagtgccatagactttaactgaagtgttttacaaagttccaaatctg agtttcaggcccacctatcctaaaccttgatgctaatgtatagctgtggctggcacctaccgtagaaaatttacttcttc acaaactctgaagacagttcccctaccacaaataaacaagtaattaaaatatgtattgtgtgtgtgcatttttatatgta aagaactacatatttgcctacagtatttatatatattttatatatatacatacacacatatatgtgtgtatatgtgtgta tgtatatatataaaatgtatataaatgctgtaggctatatatatatacacacacacata atgtgtgtgtgtatatatgt gtgtgtgtgtatatatatacatatccacatattcttgcccacattcacacaaaacagcaaaagagagaaactttagcagt taaacagaatcttttggaacataaaatgaccacaatagagagcagtttttgcatgctgtaaatttgccaagatgcccaca cactgaaactacctcccactgctgccgcaaactccctacctgtgtagcatagggcaagcttcttcttgctgcacctctca tcattccacatgcccacatctttttctctcttgatgtagatctccacgcagtcctcatctttttgcctattgttgggttc acctggagcccagttcttggcttcttctgtcagaggtttctgggttcctacccagacccacacattgttgacttttctga ttccaatccagtaataacttggtgaatagctcaatatggagtttaggtactcaatctcttctttgttttgaattgcaacc aggtgtgtgtacctttgctgacaataagcactggcctcatcataagtcatagcttccgtggaggtgttgtaagaccaggc tccactctctttaatgagaagcactagtgggagaaaaagaaaagaaatggtagagtttggtactgttgtggtttaactct gacaactgtgctttttattgtcttatttttggcaatgtttgtgacatggcccagacttttctcatcttttcaaaagtaag aagtacgtatgaagaaacagcgacttattgtttatctcttttgtgactgccacccactaggtaccttatccacactcact cacaacattatagtatacccattttgtagtagaataataatcagaataactaagctttattgagcacttagtatgcacca agaagcactgtatgaggtactttccatgaaccatgctattgaatcctcacaatgcatctgggaaataggtcattatgatc cacactttacacttaaggaaagggagacaccaagaggtaaagtaaatgaccccaagcccagggaagaacacattgcaggt agaggtcaaggatgctgccagatatcctgtgcaggacagccccagacaagcaaggatatttcagtctgaaatatctatag tgcgagaatgagaaatcttggtctaatggcactgacttacccaaagtgagagctgagagaaactgtgaagcaatcatgac ttcaagagttcttttcacccaaaggtttaggcttgaaatactttcctggggagataaaacacaaaatgaattaaagaagg aaatcgtgggtagctagttacattattctaccatgatgtttaaggcagcatcctaagattttgggcaaaggacactagtg caataatctttatttcagagtttaatcaaataaataaacaaattttaagactttcattatttaggtcaaagagaaaagac aggttttagctacaatacaataagagcttgtacagatgtggtttttattagaaggccttttgcatatctgtgtttcatgg cccgaggctgcccttataaagcgttctgcacttaccgttttgggaagcagttgttcaaacacaggatctctcaggtgggt atcactgctgcctctgtctcaggtcagtataggagttttgatgtgaagtcagccaagaacagctgaacactacttcggct gaggcccttttataggagggattgcttcctgtgaataataggaggatattgtccacatccagtaaagaggaaatccccaa tggcatccaaaaactttcccgggaatatccacgatgcttaaaattacaatgatgtcagaaactctgtctcttgaagctac ttcacctttgtccatgcctttatatcgtatatgcaattttattaatatgacaaaaatgcatgatttttaattataataac ataaagtctatgtctttaaaaagttgtaaaactttgcttgttagtagtgtctctcatgtagttgtggtagtaattagaat ttcagaaacagaaggaaaccaagaataggtttgtcatccatagtctactaccttcaatttctcattcatagctgtggata accaatcactactcattttttcttcctttttcacctgccaattcaacatatttaacatgcactgtctcacagaggaatga ctcacaaggtagatattaatcttcagattttgcacggcagttatgcctaaattaaaatattatctaaaaataatatctaa cactcaaatggttaaaataatgccttattttaaaaaaagaaaaatgggaaatagatatttacatctgggaaagtttcatg gtttgttcagtgaaaaaaataaaaaggaggccaggcacagtggctcacgcctgtaatcccaccactttgggaggccgagg caggcggatcacctgaggccgggagttcaagaccagcctgaccaacatggagaaacgccatctctactaaaaatacaaaa ttagctgggcatggtggcgcatgcctgtaatcccagctactcgggaggctgaggcaggagaatcgcttgaacccgggaag tggaggttgcagtgagccaagatcacgccagtgcactccagcctgggaaacgagtgaaactctgtcttaaaaaaaaaaaa aaaaaaagaaaagaaaagaaaaaaaataaaacggaaaactatatatatatatttaattggtcaaaattttgtttaaaatt tttgaaatgttaatgtgcaaagaataaaaattcttccacaatgttaacagtgactaactctggatggcaggatttgggat aatttttatatccttcattattattttcaggattttaaagtttttttcaatttccctttttttcacctttatagtaacaa gaatacagtttaaagaaacttgtctctaggccaggcatgatggctcatgcctgtaatcccagcactttgggaggctgagg tgggtggatcacctgaggtcaggagttccagaccagcgtggccaatatggtgaaaccctgtctctactaaaaatacaaaa attagccggggtgtagtggcgcatgcctgtaatcccagctactggggagcctgatgcaagagaatcgcttgaacccagga ggcagaggttgcagtgagctgaaatcacaccattgcactccagcctgggcgacagagcaagactccatctcaaaaaaaaa gaaaaaaagaaaaagaaaagaaaagaaatttgtttccaaatgcaacagaaggagatgtatgtggtatcctatattcctgc tcttcattttgacatttcttctgggtgattgtatacattccccatctctgcatcttaccctatctaaatgatggtaacag taaatggggatcattttaatttccatattctgtaggttttcagagctcaagtcaagctaatattctatatctacagcctt tcaaaataggaggtctatctaaaaatgtactgtcagcagacctgaacgagtagtggtaaaagcctcgtttttctctttac ttgttagcactggtctttctgtgttcataaagatgtcaagacccaaaaaaaaaacaagaaaagagaagaaaaattccaaa aaagacaactgattagaaaaaaataacttaattaacgaatttaattcaacccctatcaaaaagcatagaatttattccct ccaccttaccactctcttacatgatccagatactgacattattccaattctttatcccactttacttagctcaatgtggt tgttgcttcaataaattcagaagagtaatcactcatatagtgtttatttagattttagggcagaatgtcaagttgggtta atacattatctgtatgtattttatttttaataaagtatgaatacataatctgctatttttaaaaagcatggtcaaatgta tagagtagccaaatcttaaaaaacaatttatcttcgatatcaataaagtacctaataattatattgctaatagaaattag tcgttaacatccctagataactaactttattattgcgaatttttcataactaagtttatagtttatctcttccccttttt aaaattagttcaaagatatctaaaaatagccccagtggtgatgaagtttctattttacttacatatatatgtcctggacc cccaattataatctctaacatttattgagtgcttactatgtgccaggccatattctgagcattttgtatgttcacctatt gattattcaatccgtacaacagcctatgaaataggtactcctattatccccattttacagatgaggaaattgagaatctg gggattttatctcattcaaaagcacagagctaagggttgaaaccaggcagttgatatccagagcccactcccttacctgc tactccaaaccatgatttcttttgttgttatgccccgagattccttgttctacccaagtttcctgtactcttcttgccct cttcttcctgagacatccttgaccatcacagctctccactgagataactgtgtcctgggttctgagacatgggggctgga agggaccccagggacagtgagcagtagggagaggatgcagtgagaacagaccctggatccccggtgcataggcagggaga aagtggacaaaggaaaaaacaagcaaggcaggtggagccatgcctaggtaaagttgatccctaagccacagttcccagaa gttcctgattcaaaagcaaattttctctaaggtcaaagggcaaactgattattctaaattctaaactgattatttctaaa ttgagaaagcttcagggagagatcccaatattcgaaggataagagaaatgaggagtggaagagataggtgagtaacagta acttaaatgtagactatatataatatataatatatgtagagtatatatatataattacaatatattatatatgtggaata tatatattatttatatatatttatatattttatatatatagatatttttatattttatatataaatatagatatttttat attttatatataaatatagatatttttatatatattatatataaatatatgtaaaatactgtgaaagaagaatagaatct tgagacctcaaattcactatgccaaagggaaagttaagcttgggaaatgagtcatgcaaaaactgccttccttttgttcc caaatacctgtaatttcacatgcttactttatcttatataaaatgtagatgtactgagcatgagatccatgcataatttc cctctagtcccttctttttacatgtaaagtgtagactcactgagtgttacagagccttgccacaatgtaaacacttgtct cattgccaacccatctttcgtttattttcttcccctcctgcttgctctttcccctctaaagatggaagttcccaaaactc tctttggaaaaagcgcaggtcacagatcctacagtgatttgtgtttcttttacctgggacaaaataaacctctaatctgt tgagatatgcttcagttactttttggtttacaatatgtacatgtatgtatataatttatatgtatataatatatgtactt gttttaaccagaggtatgttattcaaaatccattcatccttacaattacctgcattctcccacagtattttctgtgtccc tgcccccgaggttgtcactgcaaatcaggtacatggatactgggagctgatgggctcccctctggctacctgggctgctg aaggggccatagacagacccagctttcctctcgtggagaggccctgggccagcgctgcgtgggagtgggattacaaccag actatagcttcttcacctgctttttcctatcaggatttcataagaggcaattgcttgttttttgagggtgggggcaaatc agggggagttgaagaggaaattgggtaagatttgaatagttgggcatgttgaatattatgaatatcatctccctcttcaa ataatccaaaatatacccccaagaaacaggctgattagaggtgcttcaaggctccactgaatctcccaagctctgaagat gtagctagctgttaccggattgccggttttcaagcctcgcctcacatggaccctcttggcagtttctcgcatgggggaag catccgctacatagatgggaatgaaaagaggaaagaagacggtgcaaactcaggcacaccccggtgtctgccaccagtgc tatttaatctctgaggtgtcacccttcctggctttattgtctcttcctggaagtctcttgtcctctcctccacacccttt aatcaggcatcaaagactttaaccagttttgctgtgtgcccaggcccactcattctcacttttatggcaaagggagtggg agacagagagatagccagaaagaagagattggggaccccaagacaaatgttagaattttaaccaaggccaccctgtggac aggagattattgggtttagtggaaagcagcactggccacaaccacacgtggcaaaagcatctatcgaggagtgaagttat atttggtgaatgtgaccgggaagcaggggcagtggtgtcctcctgccttcctgaggcactctgttcccttacctctgcga aggcttattttacccctgagtgcttagttttgaaagccttagttccctctctcccataaaaaagctctactctgctaaca tctaagttacctttgcagagtcttaggtagagggaggaaatcccaataaagattccaccctatctgcaaaatacaaacat ggtatttcttgcattcccaaaattgtgaaagaaaatgtgtatcaccacagtagagaatggcattttttgtttgatcaaaa cctaaatatatttgatgaaaatgtgtctggttctaagtttatttcccagaaagccatgtttactcacttggaatttatag acatcttataatatctgagtcgagtaggagctccgggctctacctcactcttttctcccacacccagggggaagtgtagg gttctcagactttagaataaagaggaatcacctggacaactcacctaaaatgcacatcttcaggtctcatactcagaggc tctgactcaacaggtctgggtggcgcccaagaatttgggctttaaatgagtatctcagatgattctaatacagaatgtgt aagatgaccagatcctatcacacttagatgtattggcctagggccacctaacttggagaaaatgttagtaagaccccgtg gttggtgctcagctataggtaccagaattttgatcaaaatttactatcattgtgacacttctcttcggaactggaaggcc agaaccccacttgtaaagtgctgggaaaatacaaggaaaatttagggtgagtagcattttgaattcttacacatggaaag taaatgtataagaattcttaccaataaaaaaaaagcaagagagaatagctgctaaagaattaacacaaatatgtatatat tagttattctcttttctcctctgattccagaggactttgtaattccactaattcttcttgagcttccaggatgatctgag acttgaatttttcatgtgctttttgcttcctatttggcagcatcttatcttgaagtttccgctttctgcttggggaccta aaaactaactaatgggaatttcttcaaaatgagcaaactctggtgaattcccaaagcggaagaaacaagtgaggatcggg ctggttaattaagagaacttttcctgaatgtagccagactgtttgccgactgttgttaacatgagggaagaaatacccct ggattttagaagagccccttgtttgttttccttggccatttgtgctgcttgttttgtaagtcagaaatttcctgaaggac tattattagctttgttctcacgtcagaaaacttctgctctggccacttttaaacatataacttggattttactgtattag aaaatgtaacaattacagacagcactaaaaggacaccaaagggcaaagaaaatgggtaacttttttttcttccccaaatc taaaataggtgattttggagaagtaggagaaaaacctggattttctagatctctttagagctcaacaactgatatagtta attatgtaagtctttgatatttggaaatgattggattaaccggataacaatgaatatttaaatacagtgatttggccagg agcagtggctcatgcctgtaatcccagcatttggggaggctgaggcgggtggatcacctaaggccgggagttccagacca gcctggccaacatggtgaaaccccatctctactaaaaatacaaaattagccaggcgtggtggtgcaagactgtaatccca gcaactcgggaggctgaggcaggagaattgcttgaacccgggaggcagaggttgcagtgagccaagatcacgccattgca ctccagcctgggcaacaagagcgaaattccatctcaataaataaataaataaatacagtgatttaacacaagagatttct atttcacactaatgagctctgtcactggggcaagcttctttgcctcattaagtctcagatttcccgagagcttatttatt tataccaagagtgctttactaccgtctctgctagctgtgacataatatgacaaaaggtataaatatgggaaaaggcacta atttatatcaaagcgttcttcgtttttccttgctgtgaagtttttagctaataattcataagaatataccatatttagag tgtttactatgcatgggcctggcacttcacatacattgcttcttacaaattttacaaagtgaaaggtagatattaatctc attttatggaggacaagatagagatctggagaggttacataacttgccagtgttttttcagttaataaatggtagggtgg agattcaatctgtgttactctaaagtccgtgtcctttttattggctccatgcctactcagatttaaatctcagcagggaa gtaaaccttagtttttacatgagaaaatgttacagcagccttctcggcttcctttacccccatcccagtttcacgagctt agtgccttagatcgggttcctttagaagcagacctcgaaataaggatgtgggtgccagtcatttattgaaaagatgatcc caagaaagcctagtaggagagtgaggaagtgagatggggaaaggaagaaactccacaagaagtgtgttaataagcaggtt accgctgtgggcagccatggggctcagctgcactaacaaactctgtctagtacagaaaacctcagggtctccccaaggag gggcaagaagtctgcctagggtatatatccgccaactcagtcactggctgagagctgatcctgggagggcatggttaatt cctctgcactttcaagtggattcctgtggtcagaaaaagccctctacaatgaattccagatgcttgtatttaaatctgac atgatctgaatgctgtgttgggacagggtgggcgttattagttttctgtcattactgtaacagattactacaaacctgat ggctgcaaacaacacatatttattatgtcatagtttgtgtgggtcagaagtacaggttagctcaactagtttctctgctc taggtttcacattgccaatatcaaggtgtcatccagttgggctcttcttgggaggcttggggatgaatccactttcaagc tcattcagattgttggcagaatccagttccttgtggttgcaggaccaaggtccctgttgccttgctggctgttggccagg agtcattcttagcttctagagactacctgtactctctgactcgtgtctccacttcacctttcaaaccagcagcggctagt cgagtccctctcttcaaatgtctccaactgtgccttcacctcatttctcctctgtgtaccatgtctgcctctactgcttg taagggctcatgggattacattggatttattcaatccaggataatctccatattttaaggctagctgactagtgatctta attccatctacaaagtcccttccaatagtactgtattagtccattttcatgctactgataaagacatacccaagactggg caattcacaaaagaaagaggtttaattagatttacagttccacatggctggggaagcctcacaatcatggcagaagtcaa ggaagagcaagtcatgtcttacatagatggcagcaggcaaagagagagagcttgtgcagggaactcctctttttaaaacc atcagatctcataatacttattcactatcacaagaacagcatgggaaagtcttgcccccatgattcaattactcccacca ggtccctcccacaacatgcaggaattcaagatgagatttgtgtggggacacagccaaaccatatcaagtacctagattca tgtttgattaaacaaccagggagcagaaatcttcaggagtggggggcatctttagaattctgcccaccaaggctgggcgc ggtggctcacacctgtaatcccagcactttgggaggccaaggtgggtggatcatgaggtcaagagatcgagaccaccctg gccatggtgaaaccccatttctactaaaaatacaaaaattagccaggtatggtggtgggcacctgtagtcccagctactc aggaggctgaggtaggagaatcacttgaacccaggaagcggaggttgcagtgagccaagattgcgccgctgcactccagc ctgggagacagagcaagactgtctcaaaaaaaaagaattctgcccatcatagtaggctgtcctacagagacataacccag gaattaggtgaatggctaacctaaattagcactgtgatgtgttttctgacttggtccttatagctcctctgcttagatgt ggaactaatccatgaatgcaagggtttgtctagagttttaagtgggagttaaatatccaaagtacaggagatattatggg tgcctcatccatgtccccttggcatttatctttcttggataacccaactctattagtttttatatctcacttgttcctat actctgtgaactgatgtcccataaatagacatttcattttgccagtcttcttgaacaataattacgattattaatctagc agttatcattaattggccacttcacattagacacagcacttaggacttaagaataccatgtcatttgatcatcataatat ggtcaggaattaagtattgctatccaaattttacaaagaaggcactgagggttagagtttaaataacttgcttaagatgt catagcctgtaagtgacaaaactaggactcaaatacaggtccatctgactccaaagtctatgttcttggctaccacactg cctctcctacaagtgacctgtggttttactactatattcacactctactaactttaccatctcccatgagtctgtctaga ggagggcacacacagcacagaaaacacatgaatgcaaaataaggaagggcctacttactacacagagccattctaatacc tgatgtttgctctaatccagttttactattaattagttgctggtgcccaagtttttactgagaaatggggataattttgg aagtcataatgatgccttcttctcatagggtattttatttgttgttgtatctccaggccccaacacagcctggcttttag taaatgatcaaaaatacctgttgaatgaataaatggagtcacctgaaacatgttaaacatttgttcatgtgtcctaatcg tggatttcaggatagtaagcatcctaaaaggaaagcatgcacactgttcttgctacattaatttctcacaatataaaaaa agaaaagcatctgaaaaaagctgccagccgctgtgtctcctaatatcaaactgagcacagatatggagaagctaagggag agggatgatgggccatgcctctaacctcatcatggcaaaagtcctgggggtcagacccgaggagagcaggaagtgtcttt tgagggatacatttccacagtggaaataatgagacttaaataaatattatatacacagttcaactgtttttatgtgtaaa ggtagtaggttttcacagtaaggaagcacttctttttttttttgtttgagacagagtctcgctctgtctcccagcctgga gtacagtggtgctatctcggctcactgcaatctctgcctcctggattcaagtgattctcctgcctcagcctcccgagtag ctgggacaacaggtgtgtgccattacacctggctaatttttgtatttttagcagagatgcggtttcaccatgttggccag gctgatctcgaactcctgacctcaggtgttctgcccgcctctgcctcccaatgtgctgggattacaggcatgagccactg cactcaccaagcacttctactgatagcatttacaaacccttcttagaatatttaaaaattctaagagaagagtaaattga gccttcccaactaatactaggaggttataaccttcataccaaaactggacaatgcttgcacaaaagaaggaagccaatga ggccacctagaaggaagactgggcattgggcccagtgagtcctggaaacctcatctgtgccagccaccccggcatggcct gtatgagtggatgagggtgacttgtccacagacaatagccatctagctgtgataaaggagtcaaggtagtcagctgcatc tctttcacctgtttgccaatgttacacaggttgaaaagctaaggtttatgtaaagcaagcatcaaagatgatgaaatgat caacctgacaatgagtactatgctgcattgtccagaaaggaactgtggaagattttgggctgaatttcaaaacagaattt cctcactctctggatgttggcttacttggcctttgatgttcagaggtggtgcctttgtgttgttgaacaatgttgatttt ggagagaaaacagagttgaaaaacccacaagtcattccctggggagtattaccggaatacagaggataatttcagcaagc cagcaaggcctcatctctgcttctaatagataggaagaaaggaagagaggaacaatacttttttaagaagctcagcttta tcgccttatctcatagaaagatgcctccagtctgtctggctaaaggtaattggcatgggaaagtctttatctgtgattct aacaagtggaatgtttcccttcattaagagagccttgtctggcttggggaaatgaaacactttctccgatatgagtgggc tgtaacccctgctactaaatactcagaagaaataaggcggttgtggagcagtcaggaatgagtcacttgcctccctggaa tattcagaaaactgaatcaaaagtacattcttctgggttttcttagtctaatagactaagggtctctactttgttaaatt tctgggaaacagcatagaatgggagaaaaaactggtcactgtagtcatgcaaatctgcaaaacaaacaaaaaagtctggg ta tgctgctaactagctatgtgaccttaagcaaggtattaactctctctgaatttcaggttcttcatctgttaaatagc atatctgtaaaatgggaattattttcatatcataatgctgtagctttaaaaaataaaataaaatggatgagataatcaga attaaagagcctgggatatatagttaatatatagcagcatgtaaagatcctgttagaaatgctaattttacagttaacca tttggagatgatccgccaaagctgctagtgtagaggcaactgagaatttgcctgtccttcagaatatgaataaataactg tcaatgatgtctcaagcctagaaaaacctatccatctggatgggtgggaaatttctaggctagtattgagaagcccattt cttgggaaataggtcctggactgagtgaaggaaaagaaacagtaaaacccatggtaaagcagcaaggctctctagaggct ctggagaggatgaattgaattctagaagatgaagtagggaagacgctttaccttcttgtgaaatggattcaaagattcaa agaccttcgggaatctccaattgtataaatggcaccatagctgtatgttccatggaacactacttcccagagatgcccag tgaaaaaagaatgccacagtcaaataagtttggaaacactccattatgtggccacctccttgaagactctaatgcacatt agcatgttaaacagtcttgagaagtcctgcagagcagaaattgcttcacatctgctaagccggcagtttcccaatatact tgattatggatagttttttccttacaacaccattctctgatatgcttccaatgacatgaaataaatatatatgcatgagg ttcttcattagggcatactttttaatagaaaatattgagaataatctaaatataaatgcacagcatttaccttttctgca taaactatatacaggcataccttggagatactatgggtttggttcccacaatatctccaaaaccacattcggttttatga ccactgccataaaaccagccacatgaattttttggtttcccaatgtatatcaaagttacatttttactataccatagtct attatatatacaatagcattatatctaaaaaacaacgtaaacaccttaatttaaggctgtggctggtttgattttctacc cagaccactaaaactttcttcatatcagcaataaggctgtttcactttcttactattttttgtgatagcacttttccttt ccttcaagaatttttcctttctattcacaatttgtttgatacaagaggactagattttagcttatctcagtttaaggtgt ttacattgttagctaaaaatgctaatgatcatctgagacttcagcaagtcataatcttttgctggtggaaggtcttgcct cagtgttgatgtctgctgactgggtggctttggcaatttcttaaagtaagacaacaatcaagtttgacatatcaattgac ccttcctgtcataaatgattttttttttctctgtagcctgcaatgctctttgatagcattttacccacagtagaattttc aaaattggagtcaatcctttcaaactctggtgctgttttatcaactaagtttatggagtattagaaatcccttgttgtca tttcaacaatgttcacaccatcttccccaggagtatattctacctcaagaaaccactttctttgctcatctataagaagc agctcctcatccactaaagttttatcctgagattgcaacaattcagttacatcttcaggctctacttctaattctagttc tcttgctgtttctatctcatttgtgcttactttctccgctgaagtcttgaaccccttaaagtcactcatgagggttggaa tcaacttcttacaaactcctgttgatgttgatattttgacctgctcccatgattcatgggtattcttaatggcatctaga atggtgaacgttttcagaaggttttcagttggctttgcccggatccatcagacgaatccctatctatggaagctatagat ttataaaatgtatttctttttttgtgggggcatagcgtctcaccctgtcacccaacctggaatgcagtggcacagtcata actcactgaagactcaaactcctgggctcaagtgattcttccaccttggcctcccaaaacactggattacaagcttgagc cactgtgtctagcccaaaatgtatatcataactaatgaggcttgaaagtcaaagtgactccttgatccatgggctacaga atggacgctgggttaccagacatgaaaacaatactcatctcctcatacatctccttcagagctcctgggtgagcaggccc attgtcaaatgagcagtagtatcttgaaagaaattttttttctgagcagtagatctccacagtggacttaaaatagtcag taaactatgctgtaaacagaagtgctgtcatccaagctctgtttttccactgatagggcaaaagcagagtagatttggca taattctctagggccttaggatttttggaatggcaaattgagcattggcttcaacttttttttttttttttttttttgag acagagtcttggtctgtcacccaggctggagtgcagtggtgcaatctcggcccactgcaagctctgcctcctaggttcac accattctcctgcctctgcctcctgagtagctgggactacaggcacccgccaccatgcccggctaattttttgtatttta gtacagacggggtttcgccatgttagccaggatggtctcgatctcctgacctcgtgatccacccgcctcggcctcccaaa gtgctgggattacaggcgtgagccacagcgcccagcctgtcttcaacttaaagtcgccagctgtgttagcctctaataag agagtctgcctgtcctttcaagctttgaagccaggcatcattctcttctctagctatgaaaatcttagatagcatcttct cccaataggaagccattttttatgccctaaaaatctgtcgtttggtgtagccaccttcatcattgatcttacctagatcc gctggataacttaccacagtgtctacatcattacttctgcttcaccttgcacttttatgttatggggatggctcctttcc tctaacctcataaactaacctccactagcctcacattcttcttttacagcttcctcgcctctctcagagttcacagaatt gaagaatgttgggccttggattacactttggtttaagggaatgctgtggctggtttgattttctatccagaacactaaaa ctttcttcatatcagcaataagactgtttcactttcttactattttttgtgatagcacttttcctttccttcaagaattt ttcctttctattcacaatttgaccgtttgatatgagaggcctagattttagccaatctcagtttacaccatgcctttttc actaagcttcatcattttagctttttatttaaagtaagatgtgtgacccttcctttcatttgaacacttacatgatgatg cctggcttcaaagcttgaaaggacaggcagactctcttattaggggctaacacagctggcgacttttaagttgaagccaa tgctcaatttgccattagaagccattgtagggttaattaatttgcctaattttaatattatggtgtctcagggaataagg aggcctgagtagagggagggagatggggaaacagccagtcatcagagcacacacaacatttatcaattaagtttatcacc ttgagggcacaggtcatgatacttcaaaacaattacaataataaaataaaaaatcattgatcgcagatcaccataacaga tataatgataatgaaaaatttgaagtattgtgagaattaccaaaacgtgacacacagacacaaagtgagcacatgtcatt ggaaaagtggtgctgatagacttacttcatgcagggttgccacaaatactcaatctgtaaaaaattcaattatctacata gtaccataaaaacaaggtatacctgtttatataatcaagaccaacagaaccctagagaaaatagctcactccctagctcg gagacattctaaccaacatacacttacctttctttttgctgtgtacagaattcaaatccctgtctcagcaaaattgcaaa gtatcaaatgtcatgtccatctaatactcaaaactgcaaatgttaagtcttgtaagcccagagaccactgtatatacaag tgttgctataagcattagttcttctccaaagaaaatagtccacttggtagaaacaaacaaaaagaaaaaaaaagaaagaa aaaacattttttacaagaagattcagtctcttacctacataagcaaaaatatgagatgttctcttatcatttttccatct atcttataatctttggtgctgacttagacactcattttcctttttgtacgtgaccatgtaaaagttcaagtcaagaaaaa cttgttttgacatttgttttgctgagtgatgggtccctaaaagaaatttggctttgcttttgaaaagttcagcatgatat tgtgtgaatttttcatggctaatgatttttagaacagttgtgatgtgtttaggtgttttaagaatatgaagcattcagtg gtttaagttggttgttataaaatgaaagaatatgaaggaaagccttcttgtcttagaacacactgattcacaaataagca gcttctctcaaaatgttgtaattacaaaaattccaaggcaaatataataaactccttgtcggtgctatgtctagaaactt aacagccccaaagaaagtcctgacaaggcaaaaaatatatatatatatacaaattgtggaagcagggtgttgaaagaaga ataaagactatataaggacaaactgtttaaaagggagggtatccttgaaagcttgacacttgactcttttgacgaggctg agggaaaacactcagtttcatagattgctggtacggatgtaaaatagtgacatccctatagagaggaatttggcaatatc tagcaaaagtgcttatgcatttattctttgacctagtaatcccgcttctaggattagtggtgaagatacacctcaacaat aaaaatatatatacattaggttattagttatggtttaatttttaatagcaaaatatttaaaacaacctacatgaacaaat aggagacttactgaataaactatggtatatctgtacaataaagtgcaattcacttatgttgttaatttgttccaaaaatc cagagccaaagagtatttgttatgctctctttagtataagaaaggggaaataagatatgtgtgcatctgtttatttttgt gaaaataagtacagaaaggataagtaagaaactagtaaaactagttatctcctagtgttagtagaaatagaatgaaagtg aattaggcttctttgagtatatgtttatatatagttttgacttttgaattatgtttatgtttacatagtcaaaaatataa attaatcaacagaaataacaaaaaaagaagaaatcacaagctttaaaatttaatacaaacagaaataattgaatctaaca gtatatcaaagtgataacgtaaactcagaagaaaaaaacataatccaacataccagtggaacacaatattctaactgtat acattcagtggttatagtctaaggacaagaaaaattgcaaaaatatcttgaactttagcttgtaggatttttattggtag caatactaatgtactaattctgaaattaatgttcgtgtattatagaattgagtaaatgaataaatatgttgatgttattg ggaactaaaattatcattctgggagtagagaaatataaatatggacttggcaaatgaaacaaagacctgcagagagataa ccatataaactcattattttaaaaattataagtgtcctagctctgttactgaaaaggcctagattcaatcttatcttgat agacaggagggcacccctttctcagaacatggtttccaaatgccattctccattaaaaggaacaaggtcttcttggagaa aagactgattctaggtctggattaggtaaagtacaacgttagtctggaatttcttgctgaatcagaagtaagaaagtgct caaaaacatgggaacatgtcacaaacacacgtgaggcaacttgaatcctcactggccatatttaggacaatcgagcatca aaaaaaaaaaaaatgttgagaataatggattctaacacttaaaacaaaaaataatccatagcccacagaaggggaagaga gggggagctcttatttacagatgaatatcaaatagcaaagacagaagaaatgacagaattagagaaacatcattttgcaa aacaccactgtaataatcaattcaggcaagtattattaatggatgtattactattgcgtaaaaccagttggggaacagga tattcatacagtctgaaggtgtcaccctaaacataacttattacaagtggaaaatggtgcctttacaatgaagaaatcta gcagaaaccatcttaatctagtgatcaaacttagtatcaccaataatggatcatactgagtcatgtgtctcctaatatga tgcaccaggaaggatgcaacgtcatgaacgttgtattcttttgtattcaacagaccacccagggtaaaggcagctttctc acttactaatcagaattgttggttttaattcattttggattttaagatttcttactttcttgtcagctcagaaatttatt taagatgatttttatcttttattcaatactttagcttggagaaccattcagagtttctaactcattgtattgccaaaaat agaaaacagcatggtttcttttgaaaatgtctaactttaaagttacttgtgtgtgtcactcagattcacatagctttttt gcctagtaatgtagtatcatgtggcaaggctataaaaatgtttacaatcttttatttaatatgactcttgagagtttatt ctaaggaaataattgaatagtaacaaaacactattaacacaaagcatagcaatttgatttgggcaaccaaacactggaaa caacctaaatgtccattacaggaatcatttatgaagcaaacactaaaatatttattgtgaagattatgagaacatagaag acagttatgagagtaaatttgaaaacctgaacacaaaacttacatatactccaattgtaacttataaaaaatacgtgcat ataaggataaaacagtacaaacaaaaaaatagttgcgttagattggtagaattatggctccttttgctgtcttaattttt tccttttacattttgatacattattttaattttaattttaaaattcaaaagaatttgccactcatctttgccacttcaag gaaaaaagaaatgtgttcgattattctgttcttagtatagttttggcaatttcctcacgtgtaaaaagagaatactatta ataatttcagtatctataagacaatataaaattaaagaatctagcccagtaactggtacatggaacgtaattaataaatc attatggactttttttctcacacccaagtagggaggaatcagtggtcccctagaggcccagtgtagaggtggcagcacca atccctaggggagaagatcttggtgatgataattcctgagcagacagttagctgagaattcaagagcagaaaagtaagaa agaaacaacttcttgctaacacctttccacccacgtttccctgttctgttgtactctgcttaccctttcatggatggagg cagaggaaagagaaccaagtttgctcttagtcattcactatgttgtttaatctgccttccatctttcttatcagttcaaa ttagaatgtagacctgaatttaaatccccgttctgtcagttataatgtgaccctagacaaaacacattctctgaacctca gagaacattcttcatttgtagaatgggaagattaatctatattccacttggatggcaagtcttttataaactttataacc taaacatgtgtgagttgctagtatcattatgttggtaaagttattctgagatatgataacagaactgttttgtctaactc cactagcatggttcaggtttagagagtgtggaattaaaaggctttatcctcaaatatgacttaaatccgatttttctcat ccactttcctccacaaacaaatcctcaggaaatgacaaactttacatggttaaacatcagttttgtttagtctttgacat ccacatggttaaatcatacatttgaaaactgcttatatttgtgttgtctatgtctaaattgaaaagacttattgaggaat agaagactacacatttttcagcaaacactgcacgttttgcagaatttccccaggcaccagtctccaggaatttattggct actaacaatactaagatatggatgaatgaggaaatcaaaatggagatcttgcaagttttgtgagaatgggtgaatggtcc aaatgaagagataagttgtgaaatattagtacaagtaaaaattatttacaatgaaagacattttgtcaatagctatgaga attttaccattgacccagaaattccatttctttcttcagaaatacccacgtaggtatacatataaaaagttattcattac agtatcgtttttcataggaaaaagttttaaaaatcagaagctatctaaactatggtatatctaggtcatagaaatcaaat gactaaaaatgttaatataagcatatgtttttaaattaacttggcttgggtcttcagcaaaattggcttcttaacattgc actccagagttagacttacccactcagtcacttatcatgcaggagcagactcctaataccacatatcatagagcagagta ggacacaggttctctgcaggcaggcaaatcccaaagagaagggaggaaagggctgagacactgcatggtcaatttcttct gaactctgcaatgtacggaggtggacagtgtccacaaagattgctcccctggacccaccatcataataacacaacggctt tgttttgtttttgtttttgttttttgacacggagttttgctcttgttgtccaggctggagtgcaatggtgtgatctcgac tcaccacaacctccacttcctgggttcaagtgattctcctgcctcagcctcctgagtggatgggattacaggcatgcacc accatgcccagctaattttgtatttttagtagagacgaggtttctccacgttggccaggctggtctcaaactcttaacct caggtgatccacccgtcttggcctcccaaagtgctgcgattacaggtgtgagccaccgcgcccagcccacaatggccttt tgtttacatctctagtgcagcactcatttcatgttctttcaagaagaatacatatttcatctttttattttatacagcaa ttagcacagtgcctggcataaggaaaatgatcattaaaagctgggtgaaaaacctaataaagctactgaggataggaact gcagaccagcatggaaagaaaactatgagccagatattgacatcatcctgaaaggcagaagatttagtataggcaagaag tatgcttttggaatatagaaaatctggattatgataagaaaagaatcatatttgtcttatcttacctactcacttctcag ttccacatgtttctgaggctgtttgtccttactttcttttctgttttatccactctttctgttctttagattggatcatt cctattgagctgacatcaagttaactgaccttttattttgtccaaactgctgttaaatgcatccagtgaatttttaactt tatatagtatatcttttagtcctagaatttccacatgagttttttaagtttccatttctctgctgagatctcctatttgt tcattcattatgaccatatttttctctacattattgagcataattataacagctcttctaaaattcttgtctgcacattc taacacctgaattattctggggtcagtctctgttacattgccttattacaaaaacagtataagtcacattgccttgtttc ttaatatgcaaaatgatttttgattgcagactagacattttgaattaaacattatagagattctggattctcgagagagt attgacttgttttttccatcaggcaggtaacttgactggactcaaactccaaactctaggtcctctgtaatgggcaactg cagtaatctttgtttagttctttaagacttattggccaggcacgggggctcatgcctgcaatcccagcactgtgggaggc caaggtgggaggatcacctgaggtcaggagttcgagaccagcctggcccacatggtgaaaccctgcctctactaaaaata caaaaattagccgggtgtggtggtgggcgcctgtagtcccagctactcagaaggctaaggcagaagaatcacttgaacct ggaaggcagaggttgcagtgagccgagattgtgccactatactccagcctgggtgacaaaagcgagactccctctcaaaa aaaaatttattggcactgcttggcatctgctatgaatacatgaagttcatgggtcagctatagatctgggcacgttatac acagaatttgggtctccctttctctggatttctccttttctggatttcttttctcattttccagcagctgtggttgccct aaactcggtcctctgtttctttacggcagtaagatttgggaacttttaggttttacctgcctctcagacaaaataaaaaa taattttcatcttgatgctactcctttcttccagatgtagacacctctctaatttccagttgctttttattgctctccag agtctaaagattatcattgttttctgtgggagagttggtctgataaaaactactcccccaaaactggaagctggaagctt gtaattatgaatagactttgagtagtattcttctttggaaaaggattttaactactccctatgtacttctttatttcctg tttttctcatccgtaatctttttattttcatacttcctaagtcagacaattttcctacttgaagattcagtgactgctat caaatgacccccatattactaaatacaatatccccaactgcatttataaaaagaaaatttactgtttattagtaaacaat gttgtagaatagtaaaatattgctgggctttggagccagataatcaaggttagaatcccagattctaacttactagctgg tgtattagtcctttctcatgctgctaataaagacataccccagactgggagactgggtaatttatgaagaaaagaggttt aattgactcacagttcagcatggctggggaggccttaggaaacttacagtcatggtggcagcaaggagaagttccaagca aagagggaaaagccccttataaaaccatctgatcttatgagaactcactcactatcacgagaacagcatgagggtaactg ccctcacgtttaattaccttccaccagttcccccccatgacacatggggattatgaaagctataattcaagatgagattt gggtggagaaatagccaaaccatataattccacccctggcccctctcaaatctcatgtcctcacatttcaaaactcaatc atgccctcccaactgtcccccaaggtcttaactcattccagcattaagtcaaaaatccaagttcaaagtctcatctgaga caaggcaagtcccttctgcctatgagcctataaaatcaaaagcatgttagttacttcctagatacagtgggggtacaggc gttgggtaaatacactgattccaaatgggagaaattgccaaaacaaaagagttacagaccccatgcaagtccaaaaccca atagggcagtcattaacattaaagttccaaaatgatctcctttgacttcatgtctcacatccaggtcacactgatgcaag aggtgggcttccaatggccttgggcagctctgcccctgtggctttgcagggtatagcctgcttcctgtttgctttttcac aggctgacattgagtgtctgtggcttttccatgagtatggtgcaagctgttggtggatttaccattctggggtctgggcc aggtgcagtggctcatgcctgtaatcccagcactttgggaggctgaggtgggggatcacaaggtcaggagatcgagacca tcctggctaacacggtaaaacccagtctctgcttaaaaaatacaaaaaattagccaggcgtggtggtgggtgcctgtagt cccagatacttgggaggctgaggcaggagaatggcgtgaacccaggaggtggagcttgcagcgagctgagattgtgccac tgcactccagcctgggcgacagagcaagactccatcaaaaaaaaaaacaaaaaaaccattctggggtctggagaatggta gcccttacagcaccaccaggcagtgccccagtggggactctgtgtgggggctctgaccccacatttcccttctgcacggc cctagtagaggttctccatgagggttctacccctgcagcaaacttctgcctggacatccaggcatttccatacatcctcg gaaatctaagccgcggaggttcccaaacttcaattcttgactcctgtgcacccacaggctcaataccacatgtaagccac caatgcttggtcagggcttgaaccctctgaagcaatggcctgagctgtacgttgacaccttttagcctagacatctagga cacagggcaccatgacccgaagcttcataaagtgggagggccttgggactagctgaggaaaccatttttccatcctaggc ctccaggcctgtgatgggaagggcagccatgaaggtgcctgacatgccctggagacgttttccccattgtcttggtaact aacattcagctccgtgtgcagcaccaacttacttatgcaaatttctgtcactggtttgaatttctccccagaaaacagga tttttcttttctattgcatcatcatgctgcaaattttcaaacttttatgctatgcttcctgttgaagactttgcggctta gaaatttcttcccccagatacccaaaattatctctctcaagttcaaagttccacagatatctaggggacaaaatgttgcc agtctctttgcatagcaagagtgacctttactccagttcccaacaagtttctcatctccatatgagaccatctcagcttg gacttagttgtccatgttactatcaacattttggtcaaagccattcaacaagtctctatgaagtttcaaacttccccatg ttttcctgtcttctaatagccctccaaatttttccaacctctgtctgttacccagttctaaagtcacttctacatttttg ggtatctttacagcagtggcactccccatggtactaatttactgtattagtctgttctcatgctgctaataaagacttac tcgagactgggtaatttataaagaacagaggttcaactggctcacagttcagcatggctgggaggcctcaggaaacttac aaacatggtggcagcaaagagaagttccaagcaaagagggaaaagccccttataaaaccatcagatcttgtgagaattca ctatcatgaaaatagcatgagggtaactgcccccatgattaatttacctcccacagggtccctcccatgacaggtgggga ttatgggaactacaattcaagatgagatttgggtggggacacagccataccatgccagctagagagccttaagaaagtca cctaatctccacaaataaaaggtttcctatttgttcaacaaaaataatgacaccccttttatgggatttctgtgaggaca aatgataactaacatagccttgcatagtgtctggcacaaaatagctactcaaaaaataatagaaacaacatttaaaaaat gtagactttattttttagagttttatgtacaaagcaaaattgagcagaatgtacagagagtttccgtatagcactcccta cccccaagcacagatagcctcccccagtatcagcatcccgcaccagagtggtacatttattataactgatgaatctatat tgacgtgtcattttcatccaaaatccatagtttatattagggatgcctcttggtgttgtaccttctatgggttttgacaa atgtataatgacatgtattcaccattacagtatcataaagaatagtttcactgtcctaaaaatctttgatcttcttccta ttcatcactccctccccattaatccctgacaactactgctaattttcctgtctccattgttttgtcttttcctgaatgtc atatagtttaaatatacagtatgtaggattttcaaactggtttatttcacttagtaatatgcatttgatgttcttccata tcttttcaaagcttcatagttcaatatttatagaattgaataatattccattgtctggatgtactacagtttatgtattc attcacctatcaaagaacaccttggttgcttccaagtttcaacaatcatgagtaaagctgctataaacatctatgtacat gtttttttgtgaattgaacattttcagcttttttagctccattcctaggagtgcaattgctggattgtatgataagggta tgtttagtgttgtaagaaactgccacgctcttcctaactggatgtactgttttgcattctcaccagcaatgaaagagttc ctgttgctccacatactcaccagcatttggtgtcgtcaatgttttgagcaatagcattttgatctaacttttcctaggta ttctttttgaaggaaataatatgacagataatagagaaaggatatacgaggacagttctgtcctttatttatagtccatc atttaatgaaggactctgtccacacttggtatttttaactctgatcctcctctcccatgaactctgacaatctcctaaat ccctgttgctggcacacatggttgtgtatcaggccccctgtggtctgtctgaagcatggctttttttttttttttttttt tttttttgagacggagtctcgctctgtcgcccaggctggagtgcagtggcgcgatctcggctcactgcaagctccgcctc ccgggttcacgccattctcctgcctcagcctcccgagtagctgggactacaggcgcccgccaccacgcctggctaatttt ttgtatttttagtagaggcggggtttcactgtgttagccaggatggtctcgatctcctgaccttgtgatccgcccgcctc tgcctcccaaagtgctgggattacaggcgtgagccaccgcgcccggcctttttttttttttttttttttttttgagatgg agtctgtcactctgtcacccaggctggtgcagtgatgcaatcttggctcactacaacctccatctttcaggttcaagtga ttctgccacctcagcctcccaagtacctgggattacaggtgcccgccaccacacccagctatttttttgtatttttagta gagacgtagtttcaccatgttggccaggctggtctcattcctgaccttgagtgatccacctgccttggcctcccaaagtg ctgggattacaggcatgggtcatcacatgtggcctgaagcatgactgttgctttaatcatatgaaatactgctctgtatt gttatctatttgaaatgccacacctcctgagctaaattgcaagcttttatggagcacaaaccatatttatatatattagc atgataccatgacacatatcaaaagctgttatatattgttacgtgaattgattctttctcagttaagaggacctctgtag tagcactttcataccgttaatttttcattttgtgcccagcccctactctgtgaaaaatgaaatgaatcctgttatcattt ccctcccaggccttttctccttgtggacaatgtgtggctcaagagaaaattcagtcagtaaatttgttcagtgcacaaac tctttatcacctctcactgttctcaagtgagatagaacagaacatccatccagtgtcttacaaattgtctggtatatagt aggcactcaataaatgttttttgaataaatgcatacatgaatcctattcctatatatagtatggtagacagatcattgat acccaaagatgcccaaatgctgatccccagaacttgtgaatatgttacatttcatgtcaaaagggactttgctaatgtga ttaaggattcagacccttggattgtaagattatcccggattaaccagggccaatctaatcacatgagaccttaaaaaagc agaaaacatttcccagctgggttagagagagatgagacagagtaaaaaggaaagagattcagggcatgaaaatgactcta cccactgttgctggctttgaagatagaggaactaggccacaaaacaaggagtatgagtggccttaagaaataggaaaaag ccctcatctgacagccagctagaaagcagtcctctgaccacaagaaattggattctgccaaccactcaaatgagcaagga aatggattctcccctagaacctccagaaaggaacacagctctgtaatgccttgattttagccaggtgagacctgtttcag acttttgacctatggaaatataagataataaagttttattgtatgctgctaaatttgcggtagtttattactgaagcaat ggaaagccaatacagacagaatatacagagagaaagagaatgagttctttcctgataatttgtaaatatttgggtcttca ctggacaagcttcacagaggattcactggttccctagcaaaccagcatgtccagtcctgcagcctccctttcttaggccc agcatatgtcagctgtgtgcatagaaaaatcaaagcaggaccctgagtagttggaaagaaaagatggttggaaatgggtt gcacttcaagtgaggaaacaagaggtaggagaccggcatctctttctcatatgtcccaggctgactcttgtgagttgttt tcccttggaggctatcgatgacagtcacagtaacctgatggaacctggatcatgatgaaagaagtaagtgtcaatggctc cgacttccaaggactctgatgtcccacagcactagctaaacaaagccagttggaaatgagcttaaatggggaatttcctg aatatattccctattgttaggaagccaggttggcttccttgcctacaattatgccaagcagtcacactatagagtcccta gggacatgatattaagtgattcttttaacacaaacaacttaataatcatttatactaatagcaaaacggccaacggctga tattccacttgaagtagaattggctatccaactggaagagaagacaggaagacgtgatctccagggagccactaaaagga ttggcacctgcctctggattccccttttccttatattacctctcagcactggcaggcctttatttcaggatacagtttca caagtattatgtcacgtctctgagaattatgttggtagatatttgctcctctggccagaaagacctagtttggagtctgg agtcatgaaggtgacatacatgtagctagtgacataagtgtagctagtaaaaatagtgagtaatggccctgaaattctat tgaatgcccaaagtgctgaccaggaacaagcatgctctagcttatctcacaaggaacttgacaattttcttcaaaaatcc tagtagctaagatttcttagtaacaaagccactaaggcacaattatgattaacttgacccttaggtgacttttaaggact attctataaaatattacaactaatagtggatccaagccagcacactctgctatataagattaattgacagtgtccacact ggtaaaataagttgtttcataaatacattagaattcatttgcactttctacacagccccaagtccagaactttccccaga ataggtctatgttttgcaatctgctactccatacagagatttgagttcacttggcaatttagtgctgcttatatgtgacc agttagtctgttttacttatctatgccttaaacattactatacttactaactccaagatgcctggtctcaacttgacaaa aataccccaagttgggaaatccttatgtgaatatgtagatagtcacaattgctggttgatgatgatctgtcttttcctgt atttgagaaaatggagataaaatggaccaatccaaataatggattaaacatgggaataggtgagagagagagaggaatac atggtggctctcagtgtctggcttaggcagtaaacactttcgttaataaagacggaaaataaaaaaggaataattggtgt ctaggggaaaataatgagctcaagttttaacactctgagttcccggatgtgagacatccaggcgcatttatccaagaggc agttggaagcaacgttccggagcttaggagagaggcatgaccaaaagctggtgggactgtgaaaaggtatggccattctg gaaaactgtttggcagtttcttagaaaattaaacatgtactaacaacccagcaattgtactcttgagcatttgtcccaga taaatgaaaaaaaaaaaaagcattttttttacacaaaaacatatacatgaaagttcatagaagtgttattcataaaaaac tggaaaaaactgagatgtctttattgagtgaatgcttaggcaaacggtggtctatccatacaatggaattatgcttagca ataaagagaaaagaactattgatacatgcaataacacagatgaatctcaaaggaattaatgctgagtgggaaaaaaagca catctcaaaatggtatatactgtactattttatttacttaacattttaaaaatagcaaaatcatagagatggagaacaga ttaatgggtactgtgttttgggatggggagtgagaaaagggtaaggtgtaaatataaaggggtagcacaaaagagccttg tggttgaaggattctatgtcttggttgtagtcgtgattgcaggaatctacatgtgataaaattgtatgggtctacatacg catacacacaagagcatataaaactggtgacatgtgaagaagctccgcacattgtgccaacatcagtatcctagtttcaa tatcagactacagttatacaaaacattgtcattgagggaaactgggtaaagggaacacaggacatttggcatatattttt gcaatttcctgtgaatccgtaattatttaaaaataacagatatactacatatcaaaaatttaatg cataaagttgatga gtttacctagtggatagctttgttaatatctgctataagactactgaaaatgacagttatgcaagtataagctcagagaa ctttcctcccccttcgtaaatgaaatgagcaaaagaaatgaaacaggaaaggcaagcagtactgaaaacagggaagggct cttccccatataactatatctgcgacttcaacagctattcatccagaaacacagcctcttgcgctaagaggaaactttgg ataacaatatgttttcactctccaagagagaaaatggatagattaatttttaagaaaaaaaaaaaaacctcaccaatttc atgctgtggcttgcacctttaatcccagctacctacaaggctgaggtgagaggcttacttgagcccaggagttcaaggct gcaatgagctatgattgattgtgctatcgcactccaacctggagtactaagctaagagctaagaacacagctgagagcgg agaagaaacaaacaaatctgaccaataacccccactcccctcattttactggagtgagctgagactgctggcaaacatgg cctttgacctagcctgaactgtagcaaaagtcatcagatatttttccaccaatcaacagacagaagtggggagaaaacaa tcgtagttcataactacaacaagcagataaacgaaggccatggtgagggatggaagacattgtgatatatcaaaggcagg ctcatttaaaactcaacccaaattccaaacaaaatatataattgaatatgtattaatgccaaaggagcttgagtgagctt tagcacaaaccccgccctccagcccccacccaaaaaaatcactctgttctctccccattctttgataggcatacttgctg ttttctcacagccaaggtacagaggggacttagaggaactagaactctaatacactgctagcaggaatgtaaaatgaagc atctacttcagaaaaccattttatcagtttctagaaagttaaacatagacccaccatgcagcccagccaσtctactccta agtatttacacaagagaaatgaaaacgtgtccccacacagttgtatttaaaggtgatggttagccttgtgtgtcaacttg gctaggctataatacccagttactgaatcaaatagtaatctaggtgcatctgtgaaggtattttgtagatgtggttaaca gctacaatctgttgacttcaagtaaaggagattgctcttgatagtatgggtgggcttcatccaatcaattgaaggcctta agagcaaaaagtaaggtttcccggagagaaagaaattctgcctcaagactgcagcctcaactcctgcctgagtttccagt cagccagccagcctaaagatttgctaggcattataatcacatcagctaatttcttaaaataaacctctttatatatattg atacaatgaatggttatagcagccttatttgtaatagccacaaactggaaacaacctaaatgtccttcaataagtgaata cataaacaaattgtggtatatccacaatttttacgcagcagtaaaaaggaataaatggttgaataaggaataaacacata acaaggatgaaccttaaaaccgtaaggctgaatggaaaaagtcagacaaaactaatacatactgaataattccatttata ttgaagttctagaaaatgaggactaacctatagtaacaaaaagcagaaaaattttgcccactggtgatggagggggcgca ggtattgtagagtatctgagaaaggacaactggataaaagggggcacaagaaaacttttgagggtgattgatatgttcat tatcttgtggcatggtttcataggtgcatacatatgtcaaaacatcaagttatacacttttaaaatgttcagtttactgt atatctattatacttcagtagagaggaaggaagaaagtgggcagggtgggggagaggaaaggaaacgagggaggaaaggc cctaataggaaggattttggagtttagattttaaaatgataaaggatgtttgacactctaggcatatgacgaatatagga ttatgagtccacaaaaaccaccaggaagtcatgtatgtttatacttttaagtgaaggatcagtggattatcaactcccta atgctttgcctctctatgactggctgctgtccttctcatcccaatactccttccaaagcc^'ccttgcttaaatgtaagcct tctttcctcctttcaacacatcctgcattccgtgacaaaataagttttccttaaacagaatgtacagcatattatttgta caattaaaaatttttggccaggtgtgatgactcatgcctgtaatcccagcaatttgggaggccgagatgtgtggattacc tgaggtcaggagttcgagaccagcctggccaacatggtgaaaccctgtctctactaaaaatacaaaaattagctgagtgt agtgtggcaggtacctgtaatcccagctactcaggaagctgaggcaggagaatcgcttgaacctgggaggtggaggttgc tgtgagcagagatcagactattgcattctaggctaggagacagagtgagactcggtccccaaaaaaaaacacattttttt ttaatgtttcctccttgcctgtaggaaaaaggctctgactccttagcctgggcatcagagctctatctaaatggacttta acctgattttgtggcactaattccattgcagtacttgtccgctcactggcctgtgcctctctgccactatttttggaata atgtcctctctccatcttgtttactcaactatatccaacctctaaggctgtgctcctacaaagcctcccctggctacttc agcccacagagatatttaactgctctgcagttcaggacattcttctgactctttaaatcacatttacttatatatgatct tgtgatattttttgttgacgtgtttactttaattttcttccataacctattcattcaacaaactcaacaattatttatta aatgccaagttagaaaaatattattgattttatatagattatagatatgtttgaaattttatttggcaatctgcaagtag aaaaataattataatgtggtatatctgtgatagaagta tagtgcagagaccatggggaacataatccagcctggaagtt caggagagatacgtggaagaaaggacgtcagagcctttttcctacaggcatggaagaaacattaaaaaaaattttttttt ttgagatggagtctcactctgtctcccagcctagactgtggtggtgcgatctctgctcactgcaacctctgtctcccggg ttcaagtgattctcctgcctcagcttcccaagtagctgggattacaggtacctgccacacatggatgataaatatgatca tattttcttgttcttttcctcctcagttgtcttccctgaagaaaggaatgccttttatagatgacaaactcccattctca agaacaaggatttttgaccaatttaatttaatcagatgtctggctttgacctagaaacacagtcacgaaacttggtgatt agagaccaattcccaaacatgagcatttcttaggaaacacagtaaagatctgagagacccaagagcagaagggcgagaaa ccaaaagccatcagtttgcataggaaacaccttgtttagcctaatctttttatttttattactctattagtcactacaac tattttctgattgctatggtgatagatggtttaaaacaagccttcattaagaattgtcacaccatggtctcagtcaaaaa caccaacatttttattggtattgacaattatgggaatatccaattccaagaagacaaggagacctctgaactttctaaat gaagactccaatcttcctgatctgatgggaagcagcttggcaagattaccaaccaccaccacagagagtggactctaagc taagacttaaaagataagtagaaattatccaggtaaagatgtgtacagagaaggaagtacatccaggggaaaagaacaat acgtgcaaaagtacggaaatggtaaaaagtaatactacatagtcaaagccaagcagagttcagaagggatctggtggtga aaaatacggctagagaaagcagcaaggattggcttctaaaacctatgtagtatcttggaccttaccctaaatgtaatgag aagcttctaaagaatctttcatttattcattcattgaacaaatattttgaggctttctgtgaagaacatcattctaagta gtaaagatacagcagtgaataggacacataaaatcctagatctcacagaattgacattccagagagggaaaggtagacaa taaatacataaacaaatcatttaacaagatgatttcagacaatggtacgtactgtgaaaaaaatgaaacaaggtaatgga cagcgaaaaggcactggaaggaagcctgcttacctttgcatggttagaaaagatctctctaagaaagagaccacatgtga gctgcgacctgaaggataccgagaagctaggtgtgcaaagatgtggggacagaacttttggactgaatagcaaatacaaa tgcccttgggtgcaagctttgcctgttcaaggaccaaaaagaaggccagtgtgcctgcagcatactaagcacagaggaaa acactgttatatgctgagattggaattataagtagagccagataatatagtctcttataggtcataataaggcaaccaga ttttattccaagaggatttaaaaatcactggaggttttgcactagggtgagaggtgtgatttgtatttttaaaagataat tctggagaattaactataatgaggtaggagtaaactaagttaggggctatttcagtggctcagacaagagataatggtag cttagactaggatagtagtcgtagaaataaataaaagtggcactctactttgggggtagagtctataataggtttggttt atggatcatatatgagagtaaaaaaaagaaaataaattaataatggttcctaggtttgtacctgagcaactgaataaatg ggtgctgtgaattgagataaaggagattgagaatcacaggctttgttttgcaaattaattttgagaggcttattagacat cccagtggagatttcaggtgagtggagcccattgaaaggtaagggacagggtcaggtgtggtaggtcaggcctgtgatcc caggactttggaaggccaaggcagacagatcagttgagctcaggagtttgagaccagcctgggcaacatgggaaaaccct gtctctacaaaatatgcaaaatattacctgggcatggtggcatatgactgtggtccaagccacttggggggctgagatgg gaggatcacttgagtacaggaggcggaggttgcagtgagccaagatctcgccactgcaaaccagcttaggtgacagagtg agaacctgtctcaataaataaataagaaacgtaagggaaaaggaaattaatctgatcattggcaaatgcatagtatttaa agccaggggagtagatgagatactcaaagtaggtgaagataaggaggcaatgaaggcctaggactctggtgtacatttag atggttataagaggaatagaaactggcaaaataagtaacactgagcacccaatgaggtggagaggaaagccaggagatga agcatcatagaaggcaagagaagaagggtgtcaaagaggcgaggcagtcatcaacttctgggcagtcaaataatataagg acagaaaagtgaccattggatttggaaatatgatgagcactttgagtggagtgttgagacagaagaccaattagagtaga ttgaggagataacgagaaatgagaaaatgtaacctgcaagcacagacaattcttgagagacttttctgtgaaaggaaaca gacacagagtcttagcatgtcttgtctttctatgggaaatgtaaatagtttgagatcagggatagtattttattctgctt tttgtacctctacattacctagcatagagctagctaatgtgcacttaagtatgttctcaattcttatcgcctgaatgact ggatgggtgaaagaatggatggatggatggatggatggatggaaggatggatggatggatggaagacttctgatttgcca agaagaggatactggtagcagaaataaaaacagcactggagaaagaagagtttagatttttattctttggtgtcagttag acaggaaagtaagacattagaagagtccttagataatttatgtaattgttcacttaggatttttaaatgtgatcactgat attggacatgttcctagtgaagcatttttggtgtttcactggttgaagttaataactgtaaaattatttcccgttcagga cagaaaaacagaaaacttgaagctcctattagaaagttcaagattctctggggttcttaggatttactgttcccaaaact ctgtcaagaacaagaaaatgacctgtatacttaactggtctaggcaacagtggaaagacaattctcagagaagatttgtt ttaagaagacactttccataggaatcaaacaatagctttcagtgactaacatggtaagacacagggtgttagctctttcc ttccaacctcatggctgttgtaccttacctttcgaccccgtgttcctgaaattgttaaattcataaacttaccaaggact aaccagcctctggggaattgctgtatacttagcaaacttacaatggacatatttataagccataatgataactgactaat aggaaataccctcaactgaaaatgagagatcatcatttgcaaatgagttcccttgcccaggcaactactggggaaaatgt catgcaagcaaaattaatctttgaaatcctccttttccattttttgtgtcttccttttccataggcaccagaaatatcat ggtgcctggatctcatctctacagaaaaaaaaagtgatttgataaactgatttatattgtgtccaaatgtgattgtattt tcaaagataacctaaggggagaatgctgtctggcccaacagcaggctctcgacttcatttcagacactgtggccaatggc tgggaaacaggtatgaacagtaggtttctgagtcccctggaattattccatttatgtagccacctccatgacaggaagcc tccctactcttacttcccagtttgttcattcatggcaccaggttgcagattaaaatttgctcagtgaccttttatctaat aatgtgttaccttcttctcttaaaaagtacaagggacaaatgctcatggtatacttttaggagattgtggctctctatta acagtatttattcaacaaacatttattgagcatttatatgtgcatcatgctagggactggaacctagtaagtgtagcaca tattatttcatttaatcctcacaacaaacccatgaggttggttttatgatcccaatttttcagaagaagaaactgatatt cagaaccagttaactaactggttcaaggtcatgcaatttctaagatacagaaccaagagtcaaagacatgattttaaacc aaagctttttctgctactccacattgcttccctaggtgagatctgaggcattccgcgaaaagagaagggtcataaagcca agggaagacaagcttaggaaaaaaaagggaaatgtcctaaataaacagctttcctatttaccagaaaccactagtttaaa aatataatgggaaaaatcctattcactttaacaatgttaaaaaaaaaaaagatagaagaaacatagggataaacttaaca catttgtaggatatgtaaagaaactaaaagatgttaataatggcctaaagaaaaaaaaacttacatgtatggggagatag accatcttactggattctaatatttaatagtctaggtgttccatttctcaccaaattaatgtatacatttaatacaatgt caaacgaaatatcttaggaattgcttacaaattgtcagataattacaaagtttacctgggaaatataagcatatatgaag agtgaatgggaccccaccactccccccaaaacaaaaaaggtctgaaaaggacagaaatcaaggagagtcttgcctgccag atacaaaattctattataaaggtgtattgatgaaaacaatttaatactagtgtagcaataggcagcaaagcaatgaaaca gcataaaaagaccagaactatacctaattatgatgaagatttaaggtatgataaacatgacataattcaaatcagcagaa attggcatagatagggttaagacaaatagctaatcattagaggggaggaaggaaaggagggaggataaaattaggttcct gccttcatcttacattaaaataaattccagatgtattacatttaaatttttttaaaaaaagaaaccacaaaatacttgaa gaaaatataagttgttatatagtcttttgatgggaatttttttttttttcagagacagggtcttgctctgtcacctagcc tagagtgcaatggcatgatcatggctcactgcagccttgaactcctgggctcaagtgatcctcccagctcagccccccag gtagcaggaactacaggcatgcgacaccccatccaacttattttttattttttgtagagacaggggtcttgctttgtttc ccaggcttatctcgaacttctgccttcaagcacctcagcctcccaaagagctgggctgatgggacattttttaacatagt gccacattaccataaatgaaaagcttgtaaaatactaatttttaaaactaatatatatcagaaatttttataaacaaagt taaaaagcaaacacaaaaaatttgtagcacttatgacaaatatatgtatatatatgaatacaaaaagagcctttacaaaa cagtaagaaaacaatgaatactcccaatggagtattcaaaactaaactgctaaaagcaattcaaaacaaaaaacataaac tatgcatatatgtatgtgaaaaagtttaaccttatcaaagaagtaaactctcaaagaaataaacatcaaataaggaaata gccttttcccacaaataaccaaaatctgtaagaatactgagctgcgaatgtttcagaaaaaaaaaaaaatcatacaccta gttcggcatgtaattaatatagatcagaacactttaaaaatatttataggccaggcacggtggctcatgcctataatccc agcactttgggaggccaaggcgggtggatcacctgaagtcaggagtttgagaccatcctgaccaacatggtgaaaccctg tctctactaaaaatacaaaaactagccaggcatgttggcgtatgctggtaatcctggctactcgggaggctgaggcagga gaattgcttgaacccaggaggtggaggttgcagtgagctgacattgtgccactgtactccagcctgggcaacaagagcaa aactctgtctcaaaaaataataataaataaaaataaaatatttatatactctgacccatcaatttgtccagcataattag gcatgtgtacaagggtttacacacaagaatgcctattgcaatattgcttttaatgctaaaaaaaattggggaaaatgctt taaaaatatagattaagactgtacattgtggtacagtcatataatcaatagtatacagctattatttattttcagccact gtccaaaatatagcctggcctaacaacattctgttaggatacgcaagcaccgtgaggagatcagctataaagtatcagtg tttcacaccactgctcctttgctaataaccttcaatggcttttaaagaagtaaaaaacaaaggcaaaattccttagtcag cccttaagactctctgttacttagctcaaactacccttttcaacaacactgccctaaccaggatgagttttttgcccccc tggagtacattcagcctttccttatcaaaccttcctttaaataagtatcttctccaggaccacttcactttcttccccaa tttagcattttctatatctccaggcctacctctataaagcctgtcctaaccactcaaaccctagctttttctctgaactg ctagaaatatttttctctcattggccatttaggtaaaaaggtttttactgtttattacctactcaataaaaattttcttt ttttgagacaaggtcttactctgtcgcctagaatggggggaagtggtgtgatcacaactcactgcagcttctacctccca gctcaacagtcctcccacctcagcctagtgagtagctgtgactacaggcatgtgccaccataccccactacttttcattt tttattttttgtgagatggaatctcactatgttacccaggctggtctgctgatctcaattgatcctcccactgtggcctc ccaaaatgctgggattacaggcatgagccacaatatctggccccagtaagcttttaaggccattaacatgaggaacagtg ttctttacactattttatcagctagggctttgcatggagtaggagtttagtaaatgcggttgatgggttaatcaatgtgt gaaaatattcagagccaccaaaaacagatattatgtctattctcatcaacaatcaaaattgagtaaacagccattttcta atacaggaaaccacaaaacattgaatggtgacattaaaaaattcccccagcaggagccaaccaattttttcatcctgatc caagttagcaaactgcaaaagataggaagcactaatgagtggaaatttgagtagaagcatttcttatgaaggctgtcttg actggatcacatttttattgctgttggaggtgccaaatgtgtgtgtttatgctaatcctccacctcaggcaacacacagt caaggatcctaccaagtgttaccgtcaagtgtctgttggcagctcaaggccccagcgttgttcccttgcactagggaaaa gacatattccaggtacaagtactcccactttgatgctacagaggagttgctgaactttgtgtcattaatctctcttcgtt agatcccaaccctgtttaaatcccactatctgcctactctgggtcttcaccaatttactagatcatagttggagaaaatc tacaaagccttgctccctttagatttaaacaggtctccgtttaaatttagaattgctaacttcaagcgggcccttatgcg acagtatgcctgtcagtcatactacatttcctcaattccattcatgtgactgctccatacccttccctctctcttcatac tactattatctcttcccccctccctcatttttaactgatgatcttgtttcctatttctctgagaaaatagaagccatcaa aagagagtttccacaaactcctactgccttatctagccctgtaccatatactttgcatttcctctcattaccatggatgt actgcctatctgtgcttctatctaaggctaacccttccacttcagttttgaatattatcagctcttaccaactcaaggcc attgctctagcaattctctcattctctctcattttcttccatcaagttttccttttcttcaattaacagagtagctccta aagggaaaaaaaagtcttctttttcaatgctcatcatcactggccatcagagaaatgcaaatcaaaaccacaatgagata tcatctcacaccagttagaatggcaatcattaaaaagtcaggaaacaacaggtgctggagaggatgtggagaaataggaa cacttttacactgttggtgggactgtaaactagttcaaccattgtggaagacagtgtggcgattcctcagggatctagaa ttagaaataccatttgacccagccatcccattactgggtatatacccaaaggattataaacaatgctgctataaagacac atgcacacgtatgtttattgtggcactactcacaatagcaaagacttggaaccaacccaaacgtccaacaatgatagact ggattaagaaaatgtggcacatatacaccatggaatactatgcagccataaaaaatgatgagttcatgtcctttgtaggg acatggaggaagctggaaaccatcactctcagcaaactatcacaaggacaaaaaaccaaacactgcatgttctcactcat aggtgggaattgaacaatgagaacacttggacacaggaaggggaacatcacccactggggcctgttgtgggatgagggga gtggggagggatagcattaggagatatacctaatgttaaatgatgagttaatgggtgcagcacaccaacatagcacatgt atacatatgtaacaaacctgcacgttgtgcacatgtaccctaaaacttaaagtataataaaaaaatatatatatatatat aaaacaactaaaaataaatcttctttttctgcaggatcagtccatcaccacacacacaggctgtgttttatgttgttccc cagcttaagagatcgttctccagatcccactgctccttccagttgtcacctcagttctccacttctttttgctgataaac tactctaactagttacatatgatttctgtccccaggtcccctccctcagttgttttgaacataatcatttatatcattta tcattttcactctaattgcacaaccaaaaactccctttttttttagatggagtctcactctgtcacctaggctggagtgc agtggcatgatctcggctcactccaacctccgcctcacgggttcaagtgatccccctgccttagcctcctgaatagctgg gattatacacatgcaccaccacacctggctaattgctttgtttttgtttgtgtgtgtgtgtgtttttttttttttttgga cagagtctcactctgttgcccaggctagactgcagtggcatgatctcagctcactgcaacctccacctcctgggttcaag cgattctcctgcctcagcctcccgagtagctgggactacaggcatgcaccaccatgccaggctaatttttttgtattttc agtagagaccaggtttcaccatgttggtcaggctggtcttgaactcctgacctcaaatgatctgcgcacctggacctccc aaagtgctgggattacagacttgagctactgcgccgggctattttgtgtttttagtaaagacggggtttcaccatgttgt ccaggctggtctcaaactcctgacctcaagtgatccgctcgcctcaggccctcaaagtgctgggattacaggagtgagcc accatgcctggccataaaactgccctttgttaatatgactgttggcctgcacattgtcaaatccagtggcattcatctta ctcggccaacctacggcatttgacactgtctgtctttccttctgttcctctatctgtttccagtatactggcctggcttt ctttttacctcttttatatgctcttccagtctcaggctcctttggggatttgaaggtatgttgcattttgctattcaatg aataatgacaagtaatgatcacttaagacattaagtggtcagttcctttactaggataaaaataattttcttcccaacat ggggcatattccatttccagtctgactgttctgtgtaatctttgtattccttggcagccccttttatatcagttcatcta ctgtgcaggaaattggacaaacatttgcactggtataaccaaatacagttgaacttttggcttgactcttagctgaactc accaaaaataatttctgtaagagactgagacgtctacgagtaggtttttcagaattagtaaacataaatcaaggatacac aggtagatttgaatttcagataaacaacaaatacttttttagtatgtctactgaaatatttgtatcttatctggcaattc tacctggtacagaactaatccattctcttgaaagatcttgactctgtaataagttctttggtgatggaagggaggtattt ctgtaattagagtcactgtcttcctcccagttttttatcctggcccagatctgcaatgaacacacgacagaatccagggg ggatgaagatgggtgctttgcaggaaaaaaaaattaaaaacatctgaaaaagcttttgtactaaaagaatgtgatctaaa aaagaaagcaggagaactttctgtctgcactttacatcagaacaaccttggcgtctagaagctgtgccctgtgggaagtg gtggtgcttggtaagagatgccaggaccagtggtacccactgggagcactgccaatacccagcaaggagcatgggtgcac agtaaggcattgcactgtgattcagcataaaataacaataagggaacgtcacggagaaaaggccagacttcctttgttta gaatgtgggaaatgtcttctgaaaaatggtagtaaaaaagcatgcttggatggtccactccaggcaaaactgactaatcg ggggtcagggatacaacccctgcatcatatgtttgtttctgttgggctgacatgaggttcactgtgaccactgtggttta accccatagtctcctggaaatacagccaggtcaagagagctccacataaaacataatcaaaaaaataaactcaagtttcc actgatcagcttttcacaactcttatcctttcactaactttggagcaagatttgagaattggatggctatttgagggcta tttctgcgctttagttcaatgttttgttctttctttattagagaactatggttttttattat tttacactttaagttct agggtacatgtgcacaacgtgcagatttgttacacaggtataaatgtgccatgttggtttgctgcacccatcaactcgtc atttacattaggtatttctcctaatgctatccctcccccagtcccccaccccccgacaggccctggtgtgtgatgttccc cttcctgtgtccaagtgttctgtttatgtgatagattacgtttattgatttgtgtatgttgaaccagccttgcatcacag tcacttgcttacaagaaacaaacacttcacagatggatcattatgtgtgataagtgaaatccaaggatttatgctcagag gtgggcttaacaggtaggaagagcagtattttccttcaaccatgagtgtatgcaggtttttcttttcttttttgagatgg agtctcactcttttacccaggctggcgcgcagtggtgcgatcttggctcactgtaacctctgccacctgggttcaagcaa ttctcctgcctcagcctcccaagtggctgggattacaggcacctgccactgtctccggctaatttttgtctttttagtag agatggggtttcaccatcttggccagccttgtcttgaactcctgacctcatgaatcatccttctcagcctcccaaagtgc tgggattacaggcatgagccactgcgcccagcccacaggtttttcaaagactaaacttaaaaaaaaaaaaaaaatttccc aatgaaatataaaactaaagtgctaaactgtgatagactgttttacaagaatgccagttttcacaagtgtctatagaaca tgtaatttagataggtaagatgaaattttgataatatttgatggcaaatttaaacaggtatacaacaaaaataaaattct aagcccctcaaccaactgaatggactccttctctcagccaaaggaataccaaagtaaacctgaaaaactagttttggcca ggattgggggtaggtgggggaagcccaacatgactcattattctctcctccctttggaattcaggcacaactgaatgtca gcattgacactaaaacacagatcttaagactgacaagccagactctttgtagcagagagccaggccctggaagaaatcaa gttattttatcccaaaaaatatttctttgatatattttcaaatggccctgcaaagctgtctcttgtggggaaaattgaca tgctgtacagaatttccttctctttccaagtttttactgatccaggagagatttaactaagaggctagcatgtttttttt tttttttttttgaggcggagtcttgctctgttgcccaggctggagtgcagtggcgtgatctcagctcactgcaaccttcg cctcccgggttcaagcgattctcctgcctcagcttcccgagtagctgggattacagatccatgccactatgcccagctaa tttttgtattttttgtagagacagggtttcaccatgttggccaggctagtattgaactcctgacctcgtgatccgcccac ctcggcctcccaaagtgctggcattacaggcgtgagccaccgtgcccagcacaagacatttaccgtctattctctctgaa gctactatctagaggcttcatcaacataataagacccttggtctccacaactccttatcttatcctattagtttctactg attccaggtctttagataataacaactctttcaaccaattgccaatcagaaagtctttgaatccacctatgacttaaaag ccccactccttcaagttatcccgcctttctggactgaaccaatgtacaccttatatgtgttgatggatatctgcctgtaa cttccattcccctaaaatgtataacatcaagctgtaacccaaccaccttgggcacatgttttcaggaactcatgagactg tgttgcagaccttggtcactcatatttggctcacagtaaacttctttaaatattgtatagagtttggcttttttcattga cacaggaaaaataaagaattggaaggtctttcatcagtcactgagccagcttcatatctgactgaggtcatacagttcag tgatttgtagctttgctacttagattgctatccattatctagaagcatcaggatcacgtgggacctattggaaatgcaga ctttcctcctagaacccaggaccttggaatattcttggcacatagtaggtgctcaatacatattgaactcctaggtgcaa ttcattaattcatgaattaatgaattaacacgctctcaaagtttagtgctttttcacagactagtctttctgcctcttaa gcactcagctcaccacgcttccagtctcactcccctattagtctgattaaaatctgcttacatgtgagtctgagatcaag tgttatctcttctgagaagtcttccctcactggcccaaaggaatttctcctctattttagcactgtcccagttgacttgt cattattctagtctttttcatattagttgtttttcatatatatgttattaaggaaactagtcatttcccctaatagaaca aaattgctggcctttggggttggcaatggaggggaggctcttcttgaaaagggggaagagtgttctcctaatatttttct tacgagatttatgttgctcatctttagcctttagtcccccattgcctgcctacagttggcagagaccatctgttctctca ctgtcaggaactgtctcaattcttgaagttcagagtcaaaaaagaagcaagttttcctagctctttgatcaactttcaaa gttttacttccatttgaaaatttactaagtcaccaggagatggtttatactgagaaatatccactcatactcttcctctt caactttcttccatatacaccctattacagggatatagtcttactctatagctcaaaaggatgaccctatcagaaacctg cacagtatgtaaaacattctcaccagaggttcacttgtgtatttccaccctagaatggaagctctacaaaagcacagaat gtatcattttaactttagattctattttcacacccagtgcttgacacatgatttgaagttaatatttatttatcaagtga ttgttttaaaatcatgactcactcaacaaagttataagaataagaatagtgttacagaattggtatacacaagctgacca taatcaacacacctattatcatttttttgcgacaggttctcgctgtctcaccctggctggagtggagtggcatgaccacg gttcactgcaggtttgaacttccaggctcaagcaatcctcccacctcagcctcccacatagctgagcccacaggtgtgtg ccaccatgtccagctaactttttaattctttgtagagacagggtcaccctatgttgcccaagctggtcttgaactccttg gctagagagatcctccctccaaggtcccccaaaatgctgggatctcaggcaagagccaccatgcctggccataatcaata cacttttaagaatgctagaatgttatatcagatgcatacttcagcactatctcaagcaaactggggtgtgggttattcta catataaagttcagcagtgttgttccacagtcccaaactccaactgaggtcaaatgtagggtgcagcaaggtcactgggg ctgtcatcaagggcctctccttgcactcttgccaaccctgtttcttgattgtctctaccaccatgagtcaccagcaatct cccacagtcacttgtttaaaagttcacaagtattgtgtgaattgcaggcaaccccttgactccctgattgcctggtcttc ttccttgggctctaccattttttttccccagcactctttctgctgctctaaattttaattcatgcaattccatatgtgtt tctctatcattcttcatctctttcctctcccttccatccaattttgtttgtctgtttgcttgcttgcttgctttaataca tttctctttttctgagaaggcttgagtccaaaactctcagttacctgttgttctgtttcccgttagttaatctccgaacc ttcataaattaaatctgacaaagtcccctgactaacaaaggaaatgcacaagtcacagtaaaaggggcacacacagaaca caaatagacccagggtcttttctgttcatcactcagctttttataggagatccaggagaaatgaagtggaaagggaagtg tgttgagttactatacaacacaagagtaaactttcttataagtggtaatttttttttacaggaataattgaaaatggaaa ttaccttctctactcatagtaagtactcagtgcgttcttgatgggatgagaatgtgtttgagctttagtgtaaggcagaa ttctgtttagtctgccagtattggagaaaaataaaacacaaagggactgacatgtaggaagtggcacctgggagggtctc aattcttcctattacaaaaatgccccagagaaataaaaagcttgtgtacatgttgagatgggagagttctctggcccccc tcgcaggatgtgtgacagtggggtggctctctgctgcgccaccatgagctcaaacccctcataggagggggagcacacag gcaggaaggtgcaggagctgggcgagctctttgggctctggccccgtggtactgtctagaggtgggtgcctgcaactcct gaaagcccaagtgggcatgtgttacagtgcactctttcagctttgctgtctgcagcttaagcgttaaccagctcagtttc ttcttggtacccaggtccttgtctggcatccaggaagaatcaggttacacatggacttgaaggatgaatgtgggagtttt atggagtggtggaggtggctctcagtgggatggatggggagctggaagggggatggagtgggaagatgatattctcctgg agtttggctgtccagcagccgatctcctctccagtcgtccccagcctctcgacgttcagatgctcctcttctctccttct ctgccatgctgttctgccgttca ctgcctgtctctctctggagcctggaatttggggtttatatggtacacaataaggg gcatggcaggccaaaagggaactttttaggtgcaaaaaacaggaatgcctcttctcacttagggctatagattttcaggc ttgaaggtggggcctttaccagcgaacctgtatttccctgtctcctgtgcatatcaatgtaatcaaatactgggctgatc caggatgtttctttagaccaattatgggtaaaataatttacattcaggtttttatatttgcttttgtcatttctttttaa gcaatcatgtaaaat tctatacgacagtaatagatgatagcgaacctaattaaaattaccagaaacttaagaatctcta atgatttcaactgtaactaaggttatttctctttatgttgaacaatgttgggagataagacacaagagtttctgaagtat ttcagaaacacaaagagggaggttatataaataatatttttttcctactttgggaaaatgaaagctagtcacaaagttaa acgagtggttattttaatatttaaaatacaggcttggatgtatttcctgttaaagaaaataaaatgcagaatattcaaaa cgtctgaccacccttctaagaaaatgcatctctgaggtatttttccttagaagttattgtaaaaatcctggagaagcttg aacacagcaaagcaaacaggatgcagagtttaatctgtggaaagcttagggaagaaaagcaaatcattaaaaataggtct tcctctgaagatttttaaaacgcaaagagggtggaatagcaatgataataaaaaagctggcatagagagtggcacaattt gctgtgccactgagctgactggatgtgttctgaatttctaggcattagtgtacctttccacacgcattctccctttaaaa aaaatgcccacacactgaatacttttttcatgcaatttaaaataagcgcaccatctagtttacagaaattcactagaagt tatttatcctaaaatagcagagatctagaagaattttgagctctaggacattttagacacacagaaagaagaatctggac aagtcttgaccagacatgacagaatagaaatttcttttcctatttatctctttgaataaaattttcaggatcttacagtg gacaagtttgttatctacacattgtgaagcacattgatttctcctctgtagccttaggaagatctgagaggtgactgagc tgattgaatgatccgtgaccgctctactgggaccagtagtagaactttactggtggagacctgctggaggtttgagagca gactttgaaaattactagagctacacagatactgtgtggctaactggattatgtttagaggctttcagaactatgctgct gctgctgcagtgtagccaggacgcacagagaacatctaaggctcttgaatggggcgatagggacagatttcagcagccat ctgacttcagtgctcattttgatgctttccctgcagggtgcagtgtgcagtgtgcagtgtgcagtggtgggaggctcaca caggaatacttgcttctgtagccctaatttccggttcaaactctgcattcaccttgacagattctttccttggccaaaat ttagttaggcttctgggctttctcttatgcccacctgcagactttttggtaaaatccagttttagtaaagagctctgcta agtcagtttagcaagaatccccacctcaaaagtcactatctccctccctggtagtgtctggcttgtcttcagcgagaatt ctattaggttctgttagattagaatcctccttacccttgatgcttcctcttagtattttttcatccactgactccttgac ccaccttgctcctcggctataaattcccacttgcccatactctgcagttaagactattttctccccactactgcaaaatc ccattgccatggtccctatactatctcaatggtaatgaataaagtctgccttaccatgctttaacaagtaacattgaacc atttttttctttaacaatctgctgcacaatgagattactaaaactttattccattttgccatgctggatgtcctcaatgg aatggctcttgtgagcaccaaatcattgtgagaaggaaaacccatctcttacagccccctgtaacgtgatgtatgttaca tgtgatgtatgttacatagttttttttcatgttgatcactttttgcccattttcctatatcttatcagttggaagactgt ggaagtttgtagtactaagccacaagatgactaagaagagttgaaagggcaagtggggctaaaaacagattttgtttgac ttaccccaccattccccctatcatggggctgaatctgcctggaggaaggagcatctttatctttgtactgtgaaccacac agtctagcagcagcacagccaaggcacttggggtttcatgagactaagtacatgcaattctattgtaaaggcttaaaata tatacaactgacccttgaacaacatgaatttgaattgcatggtcagttatacgcagattttcttccacctctgccacccc tgagacagtaagatcaatcaatcctcttcctcctactcctcagtctactcaaagatacttgaagtctacttgaagatgac aagcacaaagacatttatgatgatccacttccacttagtgaatagtaaatatgttttctcttcctcctaattttttaaca ctttcttctctctagcttaatttattgttaagaatacaatctataatacatatgacatacaaaatatgtcttagttgact gtttatgttatctgtaaggcttcaggtcaagagtatgctattagtggttaagttttcgaggagtcaaaaggtgtatgtgg actttcaactgcaggggggtgggcacccctgcccccatgttgttcaagggtcaactttactgccaaaggcaagcctttac atccactttttccatcccatcagtaaatggaaaaagatagctacagtatccctgcgtcaaatctttttttttgcagatca caaattggccactcaccttgctctgtgaggggtaaaatgccccactttctttagtaatatttaagttagataatatttaa gttataaagttgttctttgtaatcgttaattgtaatttttacatagtttctttcaaacagaaatagcatttttgttagat aacctcccgtatagatgatgaaactccttttaagggctatctgaattttaattccttgaaaaggcagaaattggatagct agtagtcataaatgtactgtggcttcccccaaccatctgggctatatagaagctgcatccttggactgcagtagaggagt cttacaaagcacagagcaacttctctcctgggttgcgctagttatgatggcaattttaaatgtgtacttttacccaaaga aaatccttattatcaacaatcacaatgccatcataaccatggtataaaaaattcaaaatgtcccagctgaagtggaggca aagactcaagttcatggagtcagagtttccttgctattcctctttttcaaatgaccatttagtaagcacctgaagaaaat actatggacggcattgaaaagtgaagataggtttaatcttctcgaaaatctaattctccagatgaaacgctgacacttat ccaccccacagaccctatagcagatgtgtcactggccatcacatttgacacagagaagtcataactcagtcagcacagag acatttccatgagtttctgaaccatggacagaacgtcgtctgtgggacatgaaaactggaacttagaggacaggcacatc tgagaaatgggcagtttaaaggcagaacatagcacatatgtgactgggttttagaagcaaatttacaagacgcactcttc ttcatcctaaataatctgcaaccaaagcttccaaaaaagacaatttaggaatgcagaggtgaggagtagggaggggaatg ggatgagagagagtggagattaatggtgggcagagcgaggtttagaacttagtggtttcttcaggttctgaactgaaatt tgtatactgtaaaggcacaaacaccatttttaacaaaagtgagcaggacttcctatctggttcagaaaataggtgaataa atagtacgaattattaaaaataataatttccacttatacataggaaacttgataggaaccatgataaatgcttaactctt aatcttcaaggaactctgctagggatataatattataaatcttgttttgcagatggagaaattgaattttaacccaagtt atcataacccttaaatgattaaatgatactgttacatgagaaagctgcgtatctgtttcctggatttgtagccataattt gtgtctcaagtcccttttgctgccagctatcttgggtaggtgtgttccctttgggctgtttgatacccccacatttatct tttttttttctctttttttgttgagagagtctttccctgttgcctaggctggagggcaatggcgcgatctcggctcactg caacctccgcctcctgggttcaagtgcttctcacgattctcttgtcccagcctctctaatagctcggattactggcatgc accaccacgcccacctaattttgtatttttagtagacaaggggtttctccatgttggtcagggtggtctcaaactcctga cctcaggtgatctgcctgccttggcctcccaaagtgctgggattacaggtgtgagccaccatgcctggccccaaatttat ctttaatgccccaaattatctagttcccatgactgggcttctgctttgatcctttctgcacttgctggaccctctccctg ggaaatgagattgtgtcctgagcccctagttagaggctatgtctctgctgttcctgaatgggcctcctggatgagacctc attaaaagtctaattctcttggagaattgagagatacctatttgtctcaaaatcattgaaaccaattaatgtattatgag cctctatccagtgatttgtacctcaattccccaatccagctgtcaaggccaatttgttctaccttacctagtaggtaagt ctggaattgtagctgtggcattttcagtaatggtactctaggttagcagtccccaacctttttggcaccagggaccagtt ttgtggaagacaatttttccatgaagggctgggcaggggagtggtttcaggatgaaactgttccacctcagatcatcagg cattagattctcacaaggagtgcgcaagctagatccctcacacatgcagttcacaatagggtgtgcactcccatgagaat ctaacaccgctgctgatctgacaggagacagagctcaggcagtaatactcatttgcctaccgctcacctcctgccgtgca gctcagttcctaacaggccacggaccagtactggtccacggcgcaggcatcagggacccctgttgctaggtataagcatc tggctgctgcatgtcttctgtgtagctacatctgtatgtgtatctgatgagatataaattatttgattataaattacttt cttcatattagagttgtgaatgagtatcacatataattatacataaactaggaatatgctttttaataatgtatataagt aagtttccttaactatgactttcatcttagcgtagtaagagggtgctaagaaatatttgtgatgaaaataggcattggta gagttgagaccactgggtgatgaaagagtgtaaagattttaaagccttcagatgctggttcaaggtgagaaatgtgattg ggagcaaatcaattaacttcttgaagtcttatagggcagttatgaatacttaatgttaacatatgtaaagctcttctgcc ctgtatacagtaaatgctagttagctattatgatcactactaaaatggggatgacataaacctcataaggttttaagtat tatgcaagatactatacaaagtccagtaaatatcacattcaattgaatccatgatgtccgattattttagctacttccaa gagagaaaaaaatgctgtcagttttactgttcttatagagagcaaggcagatcccaattcccaatgtggtaacgtgaaaa tttttgcatttgaatcaacaaaacactttctcctttctttcctactatttaacaactggtaagtctatactcccccaaat ctggaattctcctttcttattctttttcctcctaccaagaccgcaggatcttttacttggctataaggggtaaacctcaa gtagtacaagttctctgtattacttttatactctgtcacagattccctttgtttcctcatctccatgtgaatttagttaa attctcagcattctgatccttactatacaaggtaaatgaatataaaaacaaaacgaaacaaaaacctcttcctatttaca taaggccccaacctaatatttagtgatatatattaatgtgaacaaggaactaacgaagactgggaagaaattcacagact tgagagaagaaatggcaggatttcctgggaacaatttcatgtaacgtcaaaggtggtaaaaggtcaaatagaatgaagat ggagaataccggattttcttacaaaatgatttcccaggagatctcatcaaatgcacgaggataccttctcagtttcacct agtgagtaaaagactggtaacatagctcacttacaatttggataaacaaaactaaacaaacaacatcaaaatttcagaaa aaataatagcaaaacagaaatcaaacactcaaatttttggtccttctgtttatttcattttggatactcagtgaatgtta attaaccaggaaacttaaaagttatttcaattatgaacctcttcaatccttcatcaattattttgagtattctggtctta aaaacatctctttcttctacaaacttctgaaagagatgaacacctccacctacaccaaaataatgtgctttgctggccaa aagtacacgtccatttttacttaacagtctaaggaaagtctggtgcaaattactataataatctgggttgtaaatggttt ctgaggtgagaatgagatcatattttacaaaaagtttttcactacttagtacaagcttacaaaactcagaccactcacca gaaaaaaatcggcatttatatagttgtgttacttttggtttcctgcatcttttcacatctggctcatttacatcattttc ttcatcttccaaagtggagttagctactacattaggtaaggttacttcatcaatcaccatactgttataatcttgaaagt gaatttctttggaccctcccttgaatgcagttatacctagtaaacctgatccacaaccaagatccaagacttttttccca gcaaatttcactttggcctttgtgaaataagccaggaggtcaaaggtacattcccagatttttaagcctccctcataaac acctgtaatcagatcagagtgagaagaaaagctttttgaaactatgttttctccagggaagttctctttcaacaagatgg ttttcactactgataacttaacatgctggaaacctggtaatgtttctatgactttattttctaacatcttctttaaatct ttaggcatagcatgctctttggcagctctcaaggagggctgttttccatgtggctccaagttccttgaactgctggctgc actgagtggactgtctgtgtcttgagagggagctgcattttccattgacttatgttcccacaagtgatcctgaggcaagt caaattgttctgcagaacattttctgtccctctcttctcctttttgactttctgagactgacagctcttttgaggaatcc agggtcaaagctccatctctaatgggtgttaattcattttccagatggtcttctatagtgaaattaaactgaaaggtcat cctcttattaaatgcacacaatctttaaattcagattcttcaacttctggatagaatttgatgatacacacaaatctgcc tcaattattcaattagttttgttgggcccaatttctctttagcagcttatacatggtaacaaatatttagagatatttcc aaatgactttttagacgtctttgg.tcctctttccaagcagctctggaaagaaaaaaaaaaaaaaaagaaagaaaatgatg attaaagcaaaatggcacatttcactaaagtgtaatattaaacagccacccccacccctccctgtcccaccatacagctg ctttttcttaaaaagttgtggggaagagagagagataagagatttggacactcatacacaccttaagggttccaaagtgg gagaagaaaatcaactataaaaacaaacagaagaacaacagcaaccaccaccactaccacctggacaaacataaagtcca agatattcagacaggacagcctagctacttgctgtctttcagctgtcttgatttgtgtccaaccatattcaccccctaag cttccagaataacttcacttctgtcttttacagaagaggtgcagtattttattttggtaagtcagcgtccctttaaaaac atgcataggtatggcctggtgtgtgtaaattcatccaagacttcactccaaacatttagtcgagaacagcagccctaagt gtatagaagtgggggtaatttggcaataattagtaaagactaattcggtggcagagcaaacgcaaactagggcactgcag tagtttggagagacctgtagaaataagaagcaactttattgagaatcttctatctactgcgctagacactataccatctg cctcaattttcacagttctggcaagtgggatctttgttccctttatacaagatttacaatttgggggagaggcgggtcac ccagtcccgcggctaggaacgcgcctctttcctctcccatcacgctgcaaggcttggagtcacttccggctgcaggtccc ggaacaaatccgaccccagaagtggggacttctggccctcacctccccatttgaatgtaatgtttacagtgatccagacc tggggatgcttgcttcccgacgtgtcctgggatcgcgcttctgaaaaagctcacctcacaacgcctcctccggacctaaa tcgcgcaccagtgagtcgagtcctccaggggctagagaagcccgactttctttccggccttgagggacccgggctcaeca agaaaccagccgccctcctctctatggttttggagccggcggagagcgcgcaagggttggcgggactgcgagtttccggt ctgggctttggcgggtctggtttgaagctctcctgtttgacgaaagtatgtctcaggaaggtgcggtcccagctagcgcg gttcccctggaagaattaagtagctggccagaggagctatgccgccgggaactgccgtccgtcctgccccgactcc cat atccttccttggttgtcacttctacctagagaagggtgtgggcgggtcgcgaacctttctcttctgtcccttcagaccca ccgccaggctgggttatattaccgcggcctgaaccccctcttttctttgtcagtgagtgggatgaaaagtgagggactgg aggggaagcgacaaccgtggtagatttaagtaaggctttggccctggaaagcctcgcggacgtgttctgacccaaggttt tagcagtggatgtggcgttttcttccattccttctttcagtttttctgtactcgttgcttgcaattaagtgtaaatactt ttgctagtggataatgggggaggcaaggactgagacctgcggtatgacgatagctctggctcttaatagtttgaggtaaa gcgagatactctgagcttttgtctcccgtaaaaagggtggtgaatatgaataagggctttcttagcgttataagaattaa agggcatagttctgtggtgtgaaatctttaaaagatgttcagtaaataaaaatgattttcctccttcccctctcagacct ctttttcttctttctttctttttttttgacaagttctcactcctctcacccaggctggagtctttctgaaagagttcttc cgcttgttgttggctttcaactgttggatttgaggcgcttagcgccttcttcgtccgggtgcagcacattcttgattggt ctcatgcctttgtggttgtaaatgtgcctggaatcctagcctttcatggtaaaccatatgtatatgtatctttttcacaa catttgagcccagctttatacaattacactcaaaagaaaaaaagtaaccttcacttgagagaatctcaatactgcacaaa tattgtgcagctaaagccctatgtaatcacatagaagtcattcacctaggcattagcaaaatctcagaaggtgccaaagc ccccttttttagtttttgtgtaggtacagaactgccgtcttcaaggagtttcaacttgaaaacaaatagccaccctcaaa acattcaaaaacacttaaactgcgtgcataatgtgtgtgagacatggtgttaggctttgggagaacagagacacggaacg tgattcctcttcttccccacaagcttatagagagacttcattaagttgaaagtcaacattcccacctagctttgcacttc aaacgacatattcaaaaaagcccaaacttcctctagttttcttcatctgagtaaatggtttcacaaactgaaaccttgaa tcctctctgtctcacacacccgatcagtaagttctattgtttctgattccaaactatgtcttgaatcaatccgtttatct ccatcctcattgctaccactctgattccaaacccttatcacctctcacttggagtattaatagtttccttgtttctactc ataattcattattccaaaaaagttaagaggggaaaaacatagatctcgtcatttccctttttaaaccactttaccttcaa ggttccaggtgatctaagccttgcccttctctcatacctagttaattaactacactctgttcatgaatacattaggctca cctacctcaagatctttttgctcagcctgatttgttctctcagccttttgcatatttcatgtttatgtcttggcccaaat gtcacttccttagaggggctttttcagagccttcaatcttaggcagttcccccaaacgcagtcttacacttgtatcacat tggcctgttcagttttctaaaaagcacattaccattaaaagaaatgctcttgtttgctttgtatattttccacttctaca cattatgttgcaaagttcataaaggcaggatgttgattttcttcacagcgttaccctcagcacctagaacagtgcctgac acatagtaagcattcattaaagggctaaaaatatttcatgttttaaaaatacttgggagtctaattagacaatacttttt ttcagcttaatggtagtattttagcttcactattttaacaaatgaaaaatttgcaataaatctacaatgccattaccccc caaaatctttttcatgttttgcattttacgtattattttccaggccttacctgcatgtctgcataatcataactgactaa ttttggaacagctggtaattatttgagctttactgaaattttttcatgaggccaattctaccctactgaactcaaatttg agttaatgatgacctcattttgattgctgctgtaaaaaataagatttcggaagaggaatgaattcttgtattactgtggt aggactatgggtttttttttgtttgtttgtttgttttgagacggagtctcaccctgtcacccaggctggagtgcagtggt gcgatctcagctcacagcagccaggttcaagtgattctccttcctcagcctcccgagtagctgagattacaggcacgtgc caccatgcccggctaattttttgtatctttagtagagatggtttcaccatgttggccaggctggtctcgaactcctgacc tcgtgatccgcctgcctcagcctcccaaagtgctgggactacaggcgtgagccaccgtgcccggccgggttattcatttt tcttattaacattctttgatgattcttatggtgttgttacagtaaaacatttctaacaattattctaacaattattcttg atggtgtatatgaagaatttattgtcgtgtatttgtaagctgctatgtgcagaagaatttcagtcaaataaagttggtaa gataggtatgtaagtaatatgaaaaaagatagaaggtgatgagtgacttaggtataaattaagtacaatagaaatgttga ggaaagaaaaatttcttgtaatagaaatcggaagtacaaactgggcatggtggtgtgcatctctaatcccagctccttga gaggctggtatgggaggatcactttagcccaggagcttgaggctgcagtgaggtgtgatcatgtcaccgcactccatcct gggtgacagcaagaccgtctctctttttttttttttttgagacggagtctcgcctatgctggagtgcaatggcgcgatct tggctcactgcaacctctgcctcccagtttcaagtgattctcctgcctcagcctcctgagcagctgggattacaggtgtg cgccaccatgcccagctaattattttgtattttaagtagagacgggttctcaccatactggccaggctggtcttcaactc ctgacctcttgttcgcccatctaggtctcccaaagtgctgggattacaggtgtgagccaccccacttggccccgagcgag accctctctctaaaaaaaaataaataaataaatcataaacctgtggattattgtagcattgtttctcatctgtcaaaaat atttcatgactatgcatagtttgaaaaggcaagtttgtccctgggcaattttcaaaatatttctttaatgtgttttcaca atactgtttacctaataaatcttaagtttttaaaagcaaaattaagccagtaatttgagtccaattccaatctcttatga gtcattgcttaaatttcaaaagggttttattttttttttaggtttgttctgagtaatgaataccctattactatgatact agtatcttccttaattatcctactcattgtctcaacattctgacagttggattgagcatattcgtaagtaaaattgtttt aactgtatgatgtactttgatgttaaggtccgagtccccacatacctcggtagatgtgttcttacagttttgtattccct tgaaatgtaactgttctctatgttacagcctttataaccttcagttacttgaaatgaacaaattcattcaaattccagca cttaaaagttttaaattacattttggataaataccaaagtgttttgttgatgatgtatgtataaacaaattgtaaatatt aaacgttagttgttacgattagacctatataaaacatgatatgcagtctactgaatagctatcagcctctaacatgttta gtgtcatttagaaaatgctttctaaattgccaaaagctgattgtctaggtgataacaaatttaccatttggaggaagttg actttctcattttcatgtcttcatcagtcttacttgatgagattcattcttctagtcagaagagagtttagactgctcag tttactcatattttgagttagcttttctatttagagttcacttggttgtggaatattcatttataatttgaatctacgtt gtgtaatgggacctaatttttttttcctttgtttttgttggagtctcgttttgtcacccaggttggagtgcagtggcgtg atctttgctcactgcaacctccaccttccaggttcaggtgattctcctgcctcagtctcccaagtagctgggattacagg catgcttcaccacgcctggctaatttttgtatttttagtagagatggggtttcaccatgttggccaggctggtctcaaaa ctcctgagctcaagtgatcctcctgccttggcctccataagtgctgggattacaggcgtgagccgctgagcctggcccca gagtttgttttgttttgttttcaagacaagatctcactctattgcccaggctggagagcagtagtgcgatcatagctcac tgcagcctgaactcctgggttcaagctattctcctgcctccatcttctaaagtgctgtgattacaggtctgagccatgat gcttggcctgtgtttttgtttgtttgttttgggggacagggtcttgctttgtcaccaaaactggagtgtagtggtgcgaa catagctagctcactgcagcctccatctcccacgctcaagcaatcctctcacctcagccttccaagtagctgagaccgca ggtgcgtgctaccatgcgtggctaattttctatttatatatttattttttggtagacatgaggtcttgtcatgtttccca ggtggtctttaactcctgggctcagacagtcctcccgcctcagccacccaaagtgttgggattacaggcgtgagccacca tgcgtggcataattttttttaagtaaattatttttttatcttgagtatagaagtgattcatgttcattgtggaaaatatg aaacatatagaaaaacagaaaagattacaaaacatctaatctgaaatggttaagattttgatgagaacagtctcatctca tttccgtatattcctgccagcctatccatcattcttcgtacatgtttatctacattaaaattggtgttatattttggaaa ctttttgtttaactacattgtgaacatttttcatgttttaaaatgtcattttaatgatggcagatcctattcaatagatg tacacacacctatttaactggtccacaattgttggatatgtaggtcgtttcctttctctctttttttttttttttggcta ctacttaatagtttctctgtatagaatgtggtattttgaaagtgtatcaagctttagattggtagtattcttgcatttaa taaagggcagtggcctttgttgactgacatgacaatatttttataaaatttgttatttgctttacagaaattttgaaaat tattgtagaaatgtttttacctcatatgaaccacctgacattggaacagactttcttttcacaagtgttaccaaaggtat aatactattacctgaaaatacatgttat aggaatctagcctcagtcttagatgatttattattaattatggctctcttt ttctaatatatcaaatatattcaaaataaaaataaggagtaagtagatctcatgtgagactataatggtgttagtgtgat cattaggcagttaaaaactgttacaggctgggcacggtggctcatgcctgtaatcccagctctctgagaggctgaggtgg gcagatcatctgaggtcaggagttcgagaccacccatggtcaacatgatgaaacctcgtctctactaaaagtacaaaaaa ttagctggacatggtggcaggtgcctgtaatcccagctacttgggagactgagacaggagaattgcttgagcctgggagg cggaggttgcattgagtcaagatcgtgccattgcactccagcctgggcaataagagcgatgctccgtctcaaaaaaaaaa aaaaaaaaaaaagaacttatattttcagattgtgtggttcctttactaactgaatttaaattatttgtagtcaattttaa atgctcttgtattttaaagccactgtactccagcctgggtgacagagtgaaacccttaattcaaaaaaaaaaaaaaaaaa aagaaaagctggaatattggcaaaatcaagtaactaagagaaaacattaaattcacagaatacattattacattttagat atatatggtatatgttttctctgaaaagcacaagcataccttttttgttttaaatggagggaactaaagatactttggtg ccaaaatgaaacattatttgtaattaatctcttattgaaatgggtttctaactttagctttgaatcgtaatctttcaaat ttcttgtactcatagtcacttgatgattctctatctgaaatatttcttagaatttgttcttgaccaccagaaaaagattc aactgttacatagatgaaaatggatgttgagtgttaacaggcctatgggaaacagtattttctttagctacattgtattg ttgactgtgttgctattcttataatgtttaggtcatttaaattgttagaaagatccaagtattaagatctagggtggcta acttttcacagacaaaaagcttgtttgtaaggtcatttactatacccttaattcaggaaggttagcttgaattgggtcaa aaggaaactggttagaaaataagtgagtagtgaataggcgattcagtgcaaattccttccagaaaatacccttgtaaatg actgtatgaatgtggattcttcaagacagtcaaatttattgtgcgaaagtaatacttttattttttgcatctctaaaaca tgaactttgagtgattttttaaaaaaattgatgctattaaatagattcaaaccatagaaatggaaaataaatttctgttt ggggcttttggggggattatgttgtaaaaataccttttctctgtattttgtgcttaattaggtacaattgttaagctaga tgatagcctgtggatgttactagtgcaaaatcaaattatcgtattgtgttttctctgtaaagttttgtcttgtcttttct agtgatttctcttattcctgtttattacttgatttgtttttacagactgtgaaattattcgatgacatgatgtatgaatt aaccagtcaagccagaggactgtcaagccaaaatttggaaatccagaccactctaaggaatattttacaagtaagtcaaa tgtattagaaagcaggagagagagggagcttaaagaatgtcaaaatttttatactgatactgattagctatgtattctta tgtaatggcctaatgttggaattaaatttatagaattaaagacgtgaatatagaaacatgaattctgaataataaactct tataagaagagaag catcaagctagctgaccctacctgtattttcaaggatatgtgtggaacacctgccatgtgttttg aagtttgtgttagtattctaaatggctagacagttgttccagtatttgtagttctgatagactaaagttctgtgaaaaga - ggaagagactgtgttttgttcattgctgtatttgtagcacccagcatgctgactaataccttttcagtgcacaaaaaata tattctaagtgaaatttccttccttattcacagacaatggtgcagctcttaggagctctcacaggatgtgttcagcatat ctgtgccacacaggaatccatcattttggaaaatattcagagtctcccctcctcagtccttcatataattaaaagcacat ttgtgcattgtaaggtgagtaaaggtctaattatactttgaatggtatataatcaatgtgcataggggctgagtaaaata atgtttgtataagattttacattttagtctatattattgaaataaacttttccatagaataaagaacatgtaagtaaata attgttgcaaaaaaagtggttttaaggaagtcattaaaagtggctttttggggttttttagttttatcttatttcccctc tataaagaaagaagttttaagaatttgtgttgagacagacacagggatcctgaaatagttatgtcatgttgcattgacca atattcaattaccattatgattagatgtcagaacttccttttataaaggaaagttaatccttatttagtccatctctaca tgccagaggtagccttgaggcacaaaagcttgcctagaatttatgggtcacagacagttttaatattgctatttgttggg cgaatgaaaatcactagttaattaatacctctctttgctgataggatgctaaaaatgtcacgcacctggcctaatgttac ccttttttagttctgtatttgcaagatcatggaagtcagaaataatattttatacatgcttgcatctcttgaagcacact atatttaatggatgttcactaaacaatgaatgaatatgtgattcagtaaatttatgatctctaatagtatgaattaaagt aaatttggctcttgagctttgatttgttttttctctcatttttatttatccgtaatcagaatagtgaatctgtgtattct gggtgtttacacctagtttcagaccttctccaggctcttttcaaggaggcctattctcttcaaaagcagttaatggaact gctggacatggtttgcatggaccctttagtagatgacaatgatgatattttgaatatggtaataggtgagtgaagaaaac tttctgcttagtatatggtgactataaatcatgtatcaattaaaattgtctctaatgattcatgttattttcttactaat tatgcattaaaattgatttaaatcttaccaaataaatttttaatcttgaaatttggaatttgtaaaatttattttgggta ccttaacctagatttgcgtatttagttactgtaatttctccacaatgattaacttatataactttataatctctgaggtt gtccatattcagagacaataactttcacatttttttaaccataactgatattgagatgcagtttatatttccttccagaa tacatataaatacgtgcatatgtgtatgtaaatatgtctattctcatatacatattataatgaaataactcattttacat gtgatgcactttatactagtttatttttattttattttatttttttgagacagagtctcactgtgtagcccaggctggag tgcagtggcacaatctcggctcactgcaacctcgcctcccggactcaagcgattctcctgcctcagcctcatgagtagct gggattataggcgtccgccaccacacctggctaatttttgtatttttagtagagacagggtttcaccgtgttggccaggc tggtcttgaactcctgacctcaggtaatccacctgcctcagcctcccaaagtgctgggattacaggcatgagccaccgtg cccagccaatactagtttatttttaaagaattgctggtcgtaacacacttcattgattttatcactcattaatggattat gaacaagagtttgaaaaacaatataaaggcaaagtttgcattcaaaactttggtataaagagagtaagttggttttgtgc agtgtatcaggcacctgttgctctgcaacacaccacctcaaaatctatttattcactatttatttattcatgattctgtg agtctgcagtttagggtgggatgtcctgagacaactttctctgatccacctggggcactagctcacccatgtgacttcag tgacttcattcacatctggctgttggcagaggcagaagtacttgagaaagccatgtgcatcatccagcaggttcacccta tctcagatacctgatgccagtggtttcagggtttctaagagtagcaaaagtgtgagcaggtcgctgtgtgctagcacttt tcaagtttctgcttgccttaattttatta tgtcccccgggccacagcaggtcatagcgtttagcccagagtcattgtag aaaagtgtggattcacaaagggcagtcattgtggccatttttataaataatctaccacagactgagtaaaagccttgcat gaataccatggatattaatttgaattcttcctttttagattttctttccttagcaatttgttttgtcattttggattaga attatatctgtagaatatttcagttataatagggtacaacttttattccactgaacatctttagttttatttaggtcatc tggtaggtataaacttcagaagttaatattcaatatttataaaaaccattaacaagtgtgacacttaaatagtttaaata attcttttgacacaactgtttccaagttgtgttacgtattttaattcaatcaaatgttgaaattgttcagtagatagttt taattataggagaaactcacccccatgacatttggatgtcttaaaagttctgttatctttctttgcagttattcattctt tat ggatatctgctctgttat tccagtatggaccatgcatttcatgccaatacttggaagtttataattaagtaagtt tgtttgttattttttactttttagaaaatgttttccatattccccaatcttaattattcatgattctttagattgcattt aaaacattttgtgtgaatttaatgttcactgacactgctgtctgataatccagatattctacatgtagctctcaagccaa attggacttctttaccctgtggcctctaaaattaaaaaaaatgttcttcctagttagctagtacttcagaaataatgggc catgggccagactagaacttaaccacttttcttctgctactgttgtttaaccagctatcaagtatcctatttctaggatt agataaattgataactataattaaaactgaatataatcttttcattaggtacttttaagttgttcacacttaattccatt tgtacagtaattttaactttctgaaactgaagcattttaaagggtcaccagggatagtgcctgtagcattcatcagattc ttaggggtgagaggagatgtggttgagatgtaaaaatggttaagaatatctactttatacacatacataaaacattaaag gtcagtgtattttcaggtcttaggtacttttcttgtactaccaggacattaagttgccattcagtggttaagagtgttgc ctgggagctgtatcacatgtgcttaaatccattcttgaaatcatttactccttctgagcccttgggctatttggttaatt tctctgaacgttagtttgctcatctgaaaatggaaataataatagcaacttcttgacagggttatagtgagaattgagtt catcactgtgaaatgcttagaaatgtgcatgacacatagttaatactcaaggaattagccacatcactatcatcatcact gattatcttccactcttaccctcttccagttcattttctgcccagcagaatgatcttttaaaaagtaaatcagatcatgt tactctattgcttgaagtctatcccatttgattaagaataacaacctaatcctctgtggatgctgcctccttcaccagcc tgtctcatgctgctctccctactcttagttcctcaaacataccaaactctcctgtcccagagtcttttcgtggtttttcc atctgcctaggatgcttctctctcctattttgtgtaccttgctaactcctgcttactgtctttcagttctcagcttaaga gttatatcttcatgataacattctttgatatccttaccctaagattaagttagattgatatccttaccctaagaataagt tagattaggtctctctattgtagcaccttagactctgtcatttgacaaatcacagccctaattaattattcttaaaatta tttaacattctctctcatgctagaccacaagtttcatgcaggtaaggcggagattgtgtccatttgtttgacccctttgt ctccagggcctggtagaatgcctcatacatagtaagaattcaattaatattttacacagagaaaaaattagcaacttatt taaacaaatataactgcttcagaggtaaactgggcacatcttagttatattatgtgatatatgatgctttttgattgttt ttttaaatgttctacaaggtagatattgttagaggtcctaagttacttgatgtgttacttgtggtgattgtattcttttc tttttattcatttaggcagagccttaagcaccagtccataataaaaagccagttgaaacacaaagatataattactagct tgtgtgaagacattcttttctccttccattcttgtttacagttagctgagcagatgacacagtcagatgcacaggtaaaa tttgggctaatagcattttaaacagcaactcttattttctttggcagttagtaaatctcatttgaatgtctgggtcagtc tatttaagaggattttaatttatttcatttgggtgtttttttttgatctgtgggattatttatatcccataattactttt cacccagagcattgtattagattcctaactgctgtcattgcctctggggtctgcctggctccctctttgcttggtaactg gttggtcacagcattcttctcagaatcctttcattcttttctgcatgagaacaaaaattcttttgttcatatttgtataa gatctgatatagctgcaatcaatcttgcattttttcttcaccaacgcattgcgacctttagggatacaagtatgtttgtg catgtatatgtatgtatcagtcttttaaatttgatatagtcatacatttgtttttattttgaaaagttagagtgttgaat tggtatcccatttatgaaacattatattctaaaaatttgtagtacgattattgggaattataactcattttcctgtaaca ctgttatacatagtaccttttgctttcagactagccctcaattttatttaactatagtagtcctaaattataagattaat agtactcaggacctaacagttatatgtcatttgttttttttttttttgagatggcgtctcactctgtcacccaagctgga gtgcagtggtatgaccttggctcactgcagcctctgcctcacgggttcaagggatcgttctgccttagcctcctgagtag ctgggattataggcgcctgccaccacgcctggctaatttttttagtagagacggggtttcgccatgttggccaggctggt ctcgaactcctgacctcaggtggtccacccgccttggcctcccaaagtgctgggattacaggtgtgagccaccgcgccca gcctatatgtaataattttaatgggaccatgaattgaatatttcttccttgaatagcaatgacatagccccttctattgt acatctgcaagctgatacagggaattcctttgtacctgcgctcttccctgccagtcagctatgggggtgaaagtgtaggg gttcatccaagtcctaaaactggtagcaactcctagggcagggctgatctggaaggacagaccctaggggagggtggaac tttaaaaagaagttctgaaggtagtaagaaggaaatgaggagtagtgttaggaaggggctaacttttttcttcttgcttc tcttctttatctcacctgcccctccccttgtatcccttcttcctttttccctttccttttttgtcctcacttcattcgtg catcctttctgattcctcttaccttgctaaaaggagaagtttgtttgggtatcctatatcaatggcaggaaggttgtttt cttctttacctttatcctatagattcatattctcaacaccaacctcctcctttttcagtttccttcttgcttctcttgac accacagagtttgcagctagtacttggagaggaaaattaaacagagatacttggaccaagagtaagatgaagaaagtcta aacaacagtatagtctatagtggcaagagagagtatgggggctgcttagccagggtggctgtacataaagtatatcttca gtttatataaactgcttatagatggaaatcagaaaatttaaattctcttaactgtccaagaaaattctcattttttcaaa tttgggactgataaatgtgaccagttctgcttactgtccattgcctgaaatggagctttgaggtggactgtataatttct tcaatcttaactccaaattctgatcagcgacgccctctgctgttcactattaatatttatttaccaatcaaagtaaagta ttgaagttttcctggcagttttcactttgtgttttagtccatttaggctgctataacaaaatcccttaaactgggtaagg gattataaatattagaaatttatctctcacagttctggaagctgggaagcccaatatcaaggcaccagtagatttggtgt ctaacgagggtgtgccgtctgcttcaaaaatggccccttgttgctgcatcctcacttagtgcaaggggcaagacagctcc cttcaacctcttttataagggcacttatgtcattcatgagggcagagccctcatgacttaatcacttccccaaaggcccc acctcttaatagtatcacattgggtgttaggtgtctgggaggacaccaatcttcaagccatatcatctcacttggaaaaa agtcaaaataaaaccagtagatttaattaatattacactatttatagaagcatgtgatgtatcattccttgtattaattt cctggggttgccgtaacaagttaccacaaactaggtggcttaaaacaatagaattttattctctcacatttctagaggca gaagttcacagtgtgtcaatagggccatgttctctggaaggctttaggggagaatatatttcatatctttctcttagctt ctcggtgtcactggcaatccttagcttactttggctttctgtgtcttcacatcatctttttataagaacaccagtgatag tgattaagggcataccttactttaatatgacctcatcttaactaattatgtcttcaataaccctatttccaaataaggcc acattctgaagtattgggagttagaacttaaagctttttgggagggacacagttcaacccataacaacccctaaaatcga tatttattctcaattaagtcttgaaattggtttcaaaaagagaatattctattagagtttttaatgtatagttttaacat atagttctttagcccccaattttttttttttttttttttttttttttttttttttgagacggagtctcgctctgtcgccc aggccggactgcggactgcagtggcgcaatctcggctcactgcaagctccgcttcccgggttcacgccattcccctgcct cagcctcccgagtagctgggactacaggcgcctgccaccgcgcccggctaatttttttgtatttttagtagagacggggt ttcaccttgttagccaggatggtctcgatctcctgacctcatgatccacccgcctcggcctcccaaagtgctgggattac aggcgtgagccaccgcgcccggcctgcccccaattatttagtttttctataaacagggaaatttatttgtgtggccctta gaactaatttaatttccactctaattcctacttatgtttatataatgcttttagaaatttgtattattcagaaaataaac atatactattgtatctgttgcctacacttagattttattgcctgctatatttaaattttattagtattttaattgtttta ttaaagaaagaatgtgcctgtaatctcagcacttttgagaggccaaggcagaaggattgcttgagcccaggagtttgaga ccagactgagcaacacagggagacccccatctctacaaaaaataaaaaaattctccaggcctcatggcacatacctgtag ttctagttacttgggagactggggtgggaggatgcattgagcccaggagattgaggctgcagtgagccatgatcaggcca ctgtactccagcttggacaacagagtgagagcttgtctagatagatagatagatagataatctaaatagataatagacag attatctaaatagataatagacagattatctaaatagataatagacagattatctaaatagataatagacagattatcta aatagataatagacagattatctaaatagataatagacagattatctatctaaatagataatagattatctaaatagata atagatagatagattagatagatagatagatagatagagcttggacaacagagtgagagcctgtctagatagatagaaac aaagaaagaaagaaagaatggtgctcatattttaaagcattgaaaaatggtcttccttgcttatattacccacaccttct ttgttggcattaagatgcaaactttgttttaaacagttgagtaaatcaaagatgggactgttaagttatttgtgttattt acctgctttttgaaaatgtaaaaataaaactctaggtttaattagtagtatgctatttagtaatgaagtaaagctagagg cttcgaacaaatcttgtgtaatttcctcttgaatgagagagaaaatttaaagtaagcaaacaaataagttgtgtgtcacc actcattcagtcatttaacaagtatttccagagtacttattctgtgccaggaaatgttgtaggtgccctcaacaacttag agtctagcctgagacacaagtaagtaggtaattattatagaatggtatgatctttggaggactgggtattggctggctca tgggagtacaagataggtacccagtgatgaagtcaggaaaggtttcttatggtgatatgatgacgtctatgctgattata aggtcagtgtagaataaactttgtgcttttaaatttgcatagcactgtattagagagttcatcttcaaaataatcgaaaa ggctgagtgtggtgacccatggctgtaatcccagcactttgggaggccgaggtgggcagattgcttgagctaggagttcg agaccaggctggccaacatggtgaaaccccgtctctactaaaaatacaaaaattagccaggagtgatggtgcgcacctgt aatgccagctacttgggaggctgaggcaggaggatcacttgaacccaggaggtggaggttgaagtaagccgaggtcatgc cactgcactccagcctgggcaacagagtgagactccatctcaaaaaaaaaaaaaatgatcaaagaaaggtgaattttcat ctaccctatttctgctgaggaaaatggactattttcaaatatttttaataagggtcaaaatgagggatc (SEQ ID Nθ:12063) cctctctcggctagacgagcttccccaactggtaacccttccacaccccaatcttcatggaccagagatcttggatgttc cttccacagttcaaaagacccctttcgtcacccaccctgggtatgacactggaaatggtattcagcttcctggcacttct ggtcagcaacccagtgttgggcaacaaatgatctttgaggaacatggttttaggcggaccacaccgcccacaacggccac ccccataaggcataggccaagaccatacccgccgaatgtaggtgaggaaatccaaattggtcacattcccagggaagatg tagactatcacctgtacccacacggtccgggactcaatccaaatgcctctacaggacaagaagctctctctcagacaacc atctcatgggccccattccaggacacttctgagtacatcatttcatgtcatcctgttggcactgatgaagaacccttaca ggtaattaattgttctcttcacttctcatggggcagcacagaaaggaataagttaggtaactgaagtgaccagccctcga ataaaaagtggcttcatggccgggtgtgatggctcacgcctgtaatcccagcactttgggaggccgaggcaggtggatca tttgaggttaggagttcaagaccagcctggccaacatggtgaaacctcgtctcttgaaaaaaaaaaaaaaaaagtggctc caccttttagaacctcttagaagatggcacatttaagccctgcttttttttttttttaaatcccaatatggctctacttt ggaggacataccagagagtcactagccttttatttccatagagaaaatgaaactatttctcttattctcacacatttgag gttcctttttgagtaagatagatggttctagaaaagaaagaaagatattctacctgaatttccatttgtgtgcagaagtc taaaacactacctttacgatttgtccttgaagaaccccactatctacaacatatctaaagaaaaaaaaaaacagcgaagc tgtgcatagcag (SEQ ID NO:12064) atcaaacagaaatgactattgaaggcttgcagcccacagtggagtatgtggttagtgtctatgctcagaatccaagcgga gagagtcagcctctggttcagactgcagtaaccagtacgtaaccactgcttggtttccattttcaaagtcaaattttgtt cttgggtgtctgaatgcccacgacatgtcttttgcaattacacatagggaaagtgaacttgttggttagtttatgtcttg agctgagccctttacgaacatcttttttccttctcagtgccaagcgaggaatttacagagaaagaagttgtgaaaccacc atagttagttgctgtgctttgaatttctttttgctcaaatggcctcagcgaaatcttatttgcctatagcaaatctacaa aaaattttcctagaccgtcttttctacaactggatggtaaagttgattgaagtgtgcctcatgtagctttatgtttgggg catttgaagggctatggctggaccagagtgtaatataaatgcttaatagagaggggaaaagaagagtgtaagaaccatta tagggctgggctcacgcctgtaatcccagcattttgggaggctgaggcggatcacgaggtcaggagttcgagaccagcct gaccaacatggtgaaaccccatctctactaaaaatacaaaaattagccagtcgcggtggcacgtgcctgtaatcccagct actcacggaggctgaggcagaagaatcacttggacccaggaggcagaagttgcagtgagccaagatcatgcctctgcacc ccagcctaggtgatagagtgagactccatctcaaaaaaaaacaaaacaaaacaattataacaatttgaatctgaaccata tgcaaatcagctttaccacttccaaggtataagaaaatccaggtctatgagactaacatcacattgtaaaaatcaaatcg tggtagaatacctttaaattaatataaatacatccccattgtggggacattttgcagggtatctgcttatctcacataca ccatgttttaataagtgatgcaacattgcatattttctaaaccaagaaaaattaagcaagtgtttaagtgatttttcctt tgatagtgggttaattggacttcatcaaagaaaatggtatctgcaaaactgctttgcatgttataaaaatgcttatttca caacttgctttcacataacctcttaccattaatttgcctaacagacattgatcgccctaaaggactggcattcactgatg tggatgtcgattccatcaaaattgcttgggaaagcccacaggggcaagtttccaggtacagggtgacctactcgagccct gaggatggaatccatgagctattccctgcacctgatggtgaagaagacactgcagagctgcaaggcctcagaccgggttc tgagtacacagtcagtgtggttgccttgcacgatgatatggagagccagcccctgattggaacccagtccacaggtatat ggttaattgcacacaggtgccatgggagcagcggctttatgcctactgaatgaattatgcttcactgggctattgattcc cgtgtaagggtgaaaaagaattattaggaaagatcctctttaaagaggaatggtaagaaacaataaaacttaggtgatat ttaaggaaacaagtctgattaaaagaaattttggagtatcctggcttatacacaagaccataaagcaagacatttgaaga ggatactaaagttgtggattatttcctaagctctgactccctgtgattaccctcactatgtataaagaaaagaagtttgg cattacagagcttacttataaaaaggaacccaaactcgggcatttcatagcagcatgattctgagcacacgtgggtaaga cctttcttctctggttagatatcatatgctggtgtataattagcttaaatgattgtgatttagacacctaggaaataatc aatagggcaattgctttccataatactttatcttcttgtgctttatttctgaagcagagtagaatgctaaagatgtatcc tagtgacagcataaaccctagaggtgacagtctgtattattgcttttcgcttctcttttctgcttctgttgggagccagt tttcttcttacgccgcattacagagagaacgtcaaatttagcaagccatatctgccataggtccaaataaagagacaata aaaattattctctcttttttggatggaatactgcgtgaaatggttatccatacaaagatactttatgtagaatagaaaaa ggaggccgggtgcagtggctcacacatgtaatcctagtgctttgggaggctaagccgggagcactgattgaggccaggag ttcatgatcagcctgggcaatgaagtgagaccccgtctctacaaaaaaatatgaaaaaattagcgaggtgtggtgacaca tgcctgtagtcccagctactcaagaggctgaggtagaggatcacttgagcctacgagttcaaggctgcagtgagctatga taactccactgcactgctgcctggatgacacagagagaccgtttctaaattaattaattaacaattttaagaaagaaaaa gggccattgcttatttttccatacaaaagtaaaataaatcataatggccaataagccaatgtaacttttttttttaaggg aaagcaaaacttgtaaaacctaaaatctcttagagttttggcatttacccaaatgttttcagtgattctgagaattggtg gatataaaacacatttctcagcaaacactttcttcattttgcatcccttactgtactttcttgtactgaatctttgcttg accagggaacccacctagcccaacaagaacaatccattctacttcttggaactacgtttattttccttttcccccatttc ctataagataacctctaaccaatgacaatctcgacagctattcctgcaccaactgacctgaagttcactcaggtcacacc cacaagcctgagcgcccagtggacaccacccaatgttcagctcactggatatcgagtgcgggtgacccccaaggagaaga ccggaccaatgaaagaagtcaaccttgctcctgacagctcatccgtggttgtatcaggacttatc (SEQ ID NO: 12065) ctgcacttttgataacctgagtcccggcctggagtacaatgtcagtgtttacactgtcaaggatgacaaggaaagtgtcc ctatctctgataccatcatcccaggtaatagaaaataagctgctatcctgagagtgacattccaataagagtggggatta gcatcttaatccccagatgcttaagggtgtcaactatatttgggatttaattccgatctcccagctgcactttccaaaac caagaagtcaaagcagcgatttggacaaaatgcttgctgttaacactgctttactgtctgtgcttcactgggatgctgtg tgttgcagcgagtatgtaatggagtggcagccatggctttaactctgtattgtctgctcacatggaagtatgactaaaac actgtcacgtgtctgtactcagtactgataggctcaaagtaatatggtaaatgcatcccatcagtacatttctgcccgat tttacaatccatatcaatttccaacagctgcctatttcatcttgcagtttcaaatccttctttttgaaaattggatttta aaaaaaagttaagtaaaagtcacaccttcagggttgttctttcttgtggccttgaaagacaacattgcaaaggcctgtcc taaggataggcttgtttgtccattgggttataacataatgaaagcattggacagatcgtgtccccctttggactcttcag tagaatgcttttactaacgctaattacatgttttgattatgaatgaacctaaaatagtggcaatggccttaacctaggcc tgtctttcctcagcctgaatgtgcttttgaatggcacatttcacaccatacattcataatgcattagcgttatggccatg atgttgtcatgagttttgtatgggagaaaaaaaatcaatttatcacccatttattattttttccggttgttcatgcaagc ttattttctactaaaacagttttggaattattaaaagcattgctgatacttacttcagatattatgtctaggctctaaga atggtttcgacatcctaaacagccatatgatttttaggaatctgaacagttcaaattgtaccctttaaggatgttttcaa aatgtaaaaaatatatatatatatatatattccctaaaagaatattcctgtttattcttctagggaagcaaactgttcat gatgcttaggaagtcttttcagagaatttaaaacagattgcatattaccatcattgctttaacattccaccaattttact actagtaacctgatatacactgctttattttttcctctttttttccctctattttccttttgcctccccctccctttgct ttgtaactcaatagaggtgccccaactcactgacctaagctttgttgatataaccgattcaagcatcggcctgaggtgga ccccgctaaactcttccaccattattgggtaccgcatcacagtagttgcggcaggagaaggtatccctatttttgaagat tttgtggactcctcagtaggatactacacagtcacagggctggagccgggcattgactatgatatcagcgttatcactct cattaatggcggcgagagtgcccctactacactgacacaacaaacgggtgaattttgaaaacttctgcgtttgagacata gatggtgttgcatgctgccaccagttactccggttaaatatggatgtttcatgggggaagtcagcaattggccaaagatt cagataggtggaattggggggataaggaatcaaatgcatctgctaaactgattggagaaaaacacatgcaatatcttcag tacactctcatttaaaccacaagtagatataaagcctagagaaatacagatgtctgctctgttaaatataaaatagcaaa tgttcattcaatttgaagacctagaatttttcttcttaaataccaaacacgaataccaaattgcgtaagtaccaattgat aagaatatatcaccaaaatgtaccatcatgctcttccttctaccctttgataaactctaccatgctccttctttgtagct aaaaacccatcaaaatttagggtagagtggatgggcattgttttgaggtaggagaaaagtaaacttgggaccattctagg ttttgttgctgtcactaggtaaagaaacacctctttaaccacagtctggggacaagcatgcaacattttaaaggttctct gctgtgcatgggaaaagaaacatgctgagaaccaatttgcatgaacatgttcacttgtaagtagaattcactgaatggaa ctgtagctctagatatctcacatggggggaagtttaggaccctcttgtctttttgtctgtgtgcatgtatttctttgtaa agtactgctatgtttctctttgctgtgtggcaacttaagcctcttcggcctgggataaaataatctgcagtggtattaat aatgtacataaagtcaacatatttgaaagtagattaaaatcttttttaaatatatcaatgatggcaaaaaggttaaaggg ggcctaacagtactgtgtgtagtgttttatttttaacagtagtacactataacttaaaatagacttagattagactgttt gcatgattatgattctgtttcctttatgcatgaaatattgattttacctttccagctacttcgttagctttaattttaaa atacattaactgagtcttccttcttgttcgaaaccagctgttcctcctcccactgacctgcgattcaccaacattggtcc agacaccatgcgtgtcacctggg (SEQ ID NO: 12066) gaagagcaagaggcaggctcagcaaatggttcagccccagtccccggtggctgtcagtcaaagcaagcccggttgttatg acaatggaaaacactatcagataaatcaacagtgggagcggacctacctaggtaatgtgttggtttgtacttgttatgga ggaagccgaggttttaactgcgaaagtaaacctgaagctgaagagacttgctttgacaagtacactgggaacacttaccg agtgggtgacacttatgagcgtcctaaagactccatgatctgggactgtacctgcatcggggctgggcgagggagaataa gctgtaccatcgcaaaccgctgccatgaagggggtcagtcctacaagattggtgacacctggaggagaccacatgagact ggtggttacatgttagagtgtgtgtgtcttggtaatggaaaaggagaatggacctgcaagcccatagctgagaagtgttt tgatcatgctgctgggacttcctatgtggtcggagaaacgtgggagaagccctaccaaggctggatgatggtagattgta cttgcctgggagaaggcagcggacgcatcacttgcacttctagaaatagatgcaacgatcaggacacaaggacatcctat agaattggagacacctggagcaagaaggataatcgaggaaacctgctccagtgcatctgcacaggcaacggccgaggaga gtggaagtgtgagaggcacacctctgtgcagaccacatcgagcggatctggccccttcaccgatgttcgtgcagctgttt accaaccgcagcctcacccccagcctcctccctatggccactgtgtcacagacagtggtgtggtctactctgtggggatg cagtggttgaagacacaaggaaataagcaaatgctttgcacgtgcctgggcaacggagtcagctgccaagagacagctgt aacccagacttacggtggcaacttaaatggagagccatgtgtcttaccattcacctacaatggcaggacgttctactcct gcaccacggaagggcgacaggacggacatctttggtgcagcacaacttcgaattatgagcaggaccagaaatactctttc tgcacagaccacactgttttggttcagactcaaggaggaaattccaatggtgccttgtgccacttccccttcctatacaa caaccacaattacactgattgcacttctgagggcagaagagacaacatgaagtggtgtgggaccacacagaactatgatg ccgaccagaagtttgggttctgccccatggctgcccacgaggaaatctgcacaaccaatgaaggggtcatgtaccgcatt ggagatcagtgggataagcagcatgacatgggtcacatgatgaggtgcacgtgtgttgggaatggtcgtggggaatggac atgcattgcctactcgcaacttcgagatcagtgcattgttgatgacatcacttacaatgtgaacgacacattccacaagc gtcatgaagaggggcacatgctgaactgtacatgcttcggtcagggtcggggcaggtggaagtgtgatcccgtcgaccaa tgccaggattcagagactgggacgttttatcaaattggagattcatgggagaagtatgtgcatggtgtcagataccagtg ctactgctatggccgtggcattggggagtggcattgccaacctttacagacctatccaagctcaagtggtcctgtcgaag tatttatcactgagactccgagtcagcccaactcccaccccatccagtggaatgcaccacagccatctcacatttccaag tacattctcaggtggagacctaaaaattctgtaggccgttggaaggaagctaccataccaggccacttaaactcctacac catcaaaggcctgaagcctggtgtggtatacgagggccagctcatcagcatccagcagtacggccaccaagaagtgactc gctttgacttcaccaccaccagcaccagcacacctgtgaccagcaacaccgtgacaggagagacgactcccttttctcct cttgtggccacttctgaatctgtgaccgaaatcacagccagtagctttgtggtctcctgggtctcagcttccgacaccgt gtcgggattccgggtggaatatgagctgagtgaggagggagatgagccacagtacctggatcttccaagcacagccactt ctgtgaacatccctgacctgcttcctggccgaaaatacattgtaaatgtctatcagatatctgaggatggggagcagagt ttgatcctgtctacttcacaaacaacagcgcctgatgcccctcctgacccgactgtggaccaagttgatgacacctcaat tgttgttcgctggagcagaccccaggctcccatcacagggtacagaatagtctattcgccatcagtagaaggtagcagca cagaactcaaccttcctgaaactgcaaactccgtcaccctcagtgacttgcaacctggtgttcagtataacatcactatc tatgctgtggaagaaaatcaagaaagtacacctgttgtcattcaacaagaaaccactggcaccccacgctcagatacagt gccctctcccagggacctgcagtttgtggaagtgacagacgtgaaggtcaccatcatgtggacaccgcctgagagtgcag tgaccggctaccgtgtggatgtgatccccgtcaacctgcctggcgagcacgggcagaggctgcccatcagcaggaacacc tttgcagaagtcaccgggctgtcccctggggtcacctattacttcaaagtctttgcagtgagccatgggagggagagcaa gcctctgactgctcaacagacaaccaaactggatgctcccactaacctccagtttgtcaatgaaactgattctactgtcc tggtgagatggactccacctcgggcccagataacaggataccgactgaccgtgggccttacccgaagaggccagcccagg cagtacaatgtgggtccctctgtctccaagtaccccctgaggaatctgcagcctgcatctgagtacaccgtatccctcgt ggccataaagggcaaccaagagagccccaaagccactggagtctttaccacactgcagcctgggagctctattccacctt acaacaccgaggtgactgagaccaccatcgtgatcacatggacgcctgctccaagaattggttttaagctgggtgtacga ccaagccagggaggagaggcaccacgagaagtgacttcagactcaggaagcatcgttgtgtccggcttgactccaggagt agaatacgtctacaccatccaagtcctgagagatggacaggaaagagatgcgccaattgtaaacaaagtggtgacaccat tgtctccaccaacaaacttgcatctggaggcaaaccctgacactggagtgctcacagtctcctgggagaggagcaccacc ccagacattactggttatagaattaccacaacccctacaaacggccagcagggaaattctttggaagaagtggtccatgc tgatcagagctcctgcacttttgataacctgagtcccggcctggagtacaatgtcagtgtttacactgtcaaggatgaca aggaaagtgtccctatctctgataccatcatcccagctgttcctcctcccactgacctgcgattcaccaacattggtcca gacaccatgcgtgtcacctgggctccacccccatccattgatttaaccaacttcctggtgcgttactcacctgtgaaaaa tgaggaagatgttgcagagttgtcaatttctccttcagacaatgcagtggtcttaacaaatctcctgcctggtacagaat atgtagtgagtgtctccagtgtctacgaacaacatgagagcacacctcttagaggaagacagaaaacaggtcttgattcc ccaactggcattgacttttctgatattactgccaactcttttactgtgcactggattgctcctcgagccaccatcactgg ctacaggatccgccatcatcccgagcacttcagtgggagacctcgagaagatcgggtgccccactctcggaattccatca ccctcaccaacctcactccaggcacagagtatgtggtcagcatcgttgctcttaatggcagagaggaaagtcccttattg attggccaacaatcaacagtttctgatgttccgagggacctggaagttgttgctgcgacccccaccagcctactgatcag ctgggatgctcctgctgtcacagtgagatattacaggatcacttacggagaaacaggaggaaatagccctgtccaggagt tcactgtgcctgggagcaagtctacagctaccatcagcggccttaaacctggagttgattataccatcactgtgtatgct gtcactggccgtggagacagccccgcaagcagcaagccaatttccattaattaccgaacagaaattgacaaaccatccca gatgcaagtgaccgatgttcaggacaacagcattagtgtcaagtggctgccttcaagttcccctgttactggttacagag taaccaccactcccaaaaatggaccaggaccaacaaaaactaaaactgcaggtccagatcaaacagaaatgactattgaa ggcttgcagcccacagtggagtatgtggttagtgtctatgctcagaatccaagcggagagagtcagcctctggttcagac tgcagtaaccaacattgatcgccctaaaggactggcattcactgatgtggatgtcgattccatcaaaattgcttgggaaa gcccacaggggcaagtttccaggtacagggtgacctactcgagccctgaggatggaatccatgagctattccctgcacct gatggtgaagaagacactgcagagctgcaaggcctcagaccgggttctgagtacacagtcagtgtggttgccttgcacga tgatatggagagccagcccctgattggaacccagtccacagctattcctgcaccaactgacctgaagttcactcaggtca cacccacaagcctgagcgcccagtggacaccacccaatgttcagctcactggatatcgagtgcgggtgacccccaaggag aagaccggaccaatgaaagaaatcaaccttgctcctgacagctcatccgtggttgtatcaggacttatggtggccaccaa atatgaagtgagtgtctatgctcttaaggacactttgacaagcagaccagctcagggtgttgtcaccactctggagaatg tcagcccaccaagaagggctcgtgtgacagatgctactgagaccaccatcaccattagctggagaaccaagactgagacg atcactggcttccaagttgatgccgttccagccaatggccagactccaatccagagaaccatcaagccagatgtcagaag ctacaccatcacaggtttacaaccaggcactgactacaagatctacctgtacaccttgaatgacaatgctcggagctccc ctgtggtcatcgacgcctccactgccattgatgcaccatccaacctgcgtttcctggccaccacacccaattccttgctg gtatcatggcagccgccacgtgccaggattaccggctacatcatcaagtatgagaagcctgggtctcctcccagagaagt ggtccctcggccccgccctggtgtcacagaggctactattactggcctggaaccgggaaccgaatatacaatttatgtca ttgccctgaagaataatcagaagagcgagcccctgattggaaggaaaaagacagacgagcttccccaactggtaaccctt ccacaccccaatcttcatggaccagagatcttggatgttccttccacagttcaaaagacccctttcgtcacccaccctgg gtatgacactggaaatggtattcagcttcctggcacttctggtcagcaacccagtgttgggcaacaaatgatctttgagg aacatggttttaggcggaccacaccgcccacaacggccacccccataaggcataggccaagaccatacccgccgaatgta ggacaagaagctctctctcagacaaccatctcatgggccccattccaggacacttctgagtacatcatttcatgtcatcc tgttggcactgatgaagaacccttacagttcagggttcctggaacttctaccagtgccactctgacaggcctcaccagag gtgccacctacaacatcatagtggaggcactgaaagaccagcagaggcataaggttcgggaagaggttgttaccgtgggc aactctgtcaacgaaggcttgaaccaacctacggatgactcgtgctttgacccctacacagtttcccattatgccgttgg agatgagtgggaacgaatgtctgaatcaggctttaaactgttgtgccagtgcttaggctttggaagtggtcatttcagat gtgattcatctagatggtgccatgacaatggtgtgaactacaagattggagagaagtgggaccgtcagggagaaaatggc cagatgatgagctgcacatgtcttgggaacggaaaaggagaattcaagtgtgaccctcatgaggcaacgtgttacgatga tgggaagacataccacgtaggagaacagtggcagaaggaatatctcggtgccatttgctcctgcacatgctttggaggcc agcggggctggcgctgtgacaactgccgcagacctgggggtgaacccagtcccgaaggcactactggccagtcctacaac cagtattctcagagataccatcagagaacaaacactaatgttaattgcccaattgagtgcttcatgcctttagatgtaca ggctgacagagaagattcccgagagtaaatcatctttccaatccagaggaacaagcatgtctctctgccaagatccatct aaactggagtgatgttagcagacccagcttagagttcttctttctttcttaagccctttgctctggaggaagttctccag cttcagctcaactcacagcttctccaagcatcaccctgggagtttcctgagggttttctcataaatgagggctgcacatt gcctgttctgcttcgaagtattcaataccgctcagtattttaaatgaagtgattctaagatttggtttgggatcaatagg aaagcatatgcagccaaccaagatgcaaatgttttgaaatgatatgaccaaaattttaagtaggaaagtcacccaaacac ttctgctttcacttaagtgtctggcccgcaatactgtaggaacaagcatgatcttgttactgtgatattttaaatatcca cagtactcactttttccaaatgatcctagtaattgcctagaaatatctttctcttacctgttatttatcaatttttccca gtatttttatacggaaaaaattgtattgaaaacacttagtatgcagttgataagaggaatttggtataattatggtgggt gattattttttatactgtatgtgccaaagctttactactgtggaaagacaactgttttaataaaagatttacattccaca (SEQ ID Nθ:12067) cctctctcggctagacgagcttccccaactggtaacccttccacaccccaatcttcatggaccagagatcttggatgttc cttccacagttcaaaagacccctttcgtcacccaccctgggtatgacactggaaatggtattcagcttcctggcacttct ggtcagcaacccagtgttgggcaacaaatgatctttgaggaacatggttttaggcggaccacaccgcccacaacggccac ccccataaggcataggccaagaccatacccgccgaatgtaggtgaggaaatccaaattggtcacattcccagggaagatg tagactatcacctgtacccacacggtccgggactcaatccaaatgcctctacaggacaagaagctctctctcagacaacc atctcatgggccccattccaggacacttctgagtacatcatttcatgtcatcctgttggcactgatgaagaacccttaca ggtaattaattgttctcttcacttctcatggggcagcacagaaaggaataagttaggtaactgaagtgaccagccctcga ataaaaagtggcttcatggccgggtgtgatggctcacgcctgtaatcccagcactttgggaggccgaggcaggtggatca tttgaggttaggagttcaagaccagcctggccaacatggtgaaacctcgtctcttgaaaaaaaaaaaaaaaaagtggctc caccttttagaacctcttagaagatggcacatttaagccctgcttttttttttttttaaatcccaatatggctctacttt ggaggacataccagagagtcactagccttttatttccatagagaaaatgaaactatttctcttattctcacacatttgag gttcctttttgagtaagatagatggttctagaaaagaaagaaagatattctacctgaatttccatttgtgtgcagaagtc taaaacactacctttacgatttgtccttgaagaaccccactatctacaacatatctaaagaaaaaaaaaaacagcgaagc tgtgcatagcagatcaaacagaaatgactattgaaggcttgcagcccacagtggagtatgtggttagtgtctatgctcag aatccaagcggagagagtcagcctctggttcagactgcagtaaccagtacgtaaccactgcttggtttccattttcaaag tcaaattttgttcttgggtgtctgaatgcccacgacatgtcttttgcaattacacatagggaaagtgaacttgttggtta gtttatgtcttgagctgagccctttacgaacatcttttttccttctcagtgccaagcgaggaatttacagagaaagaagt tgtgaaaccaccatagttagttgctgtgctttgaatttctttttgctcaaatggcctcagcgaaatcttatttgcctata gcaaatctacaaaaaattttcctagaccgtcttttctacaactggatggtaaagttgattgaagtgtgcctcatgtagct ttatgtttggggcatttgaagggctatggctggaccagagtgtaatataaatgcttaatagagaggggaaaagaagagtg taagaaccattatagggctgggctcacgcctgtaatcccagcattttgggaggctgaggcggatcacgaggtcaggagtt cgagaccagcctgaccaacatggtgaaaccccatctctactaaaaatacaaaaattagccagtcgcggtggcacgtgcct gtaatcccagctactcacggaggctgaggcagaagaatcacttggacccaggaggcagaagttgcagtgagccaagatca tgcctctgcaccccagcctaggtgatagagtgagactccatctcaaaaaaaaacaaaacaaaacaattataacaatttga atctgaaccatatgcaaatcagctttaccacttccaaggtataagaaaatccaggtctatgagactaacatcacattgta aaaatcaaatcgtggtagaatacctttaaattaatataaatacatccccattgtggggacattttgcagggtatctgctt atctcacatacaccatgttttaataagtgatgcaacattgcatattttctaaaccaagaaaaattaagcaagtgtttaag tgatttttcctttgatagtgggttaattggacttcatcaaagaaaatggtatctgcaaaactgctttgcatgttataaaa atgcttatttcacaacttgctttcacataacctcttaccattaatttgcctaacagacattgatcgccctaaaggactgg cattcactgatgtggatgtcgattccatcaaaattgcttgggaaagcccacaggggcaagtttccaggtacagggtgacc tactcgagccctgaggatggaatccatgagctattccctgcacctgatggtgaagaagacactgcagagctgcaaggcct cagaccgggttctgagtacacagtcagtgtggttgccttgcacgatgatatggagagccagcccctgattggaacccagt ccacaggtatatggttaattgcacacaggtgccatgggagcagcggctttatgcctactgaatgaattatgcttcactgg gctattgattcccgtgtaagggtgaaaaagaattattaggaaagatcctctttaaagaggaatggtaagaaacaataaaa cttaggtgatatttaaggaaacaagtctgattaaaagaaattttggagtatcctggcttatacacaagaccataaagcaa gacatttgaagaggatactaaagttgtggattatttcctaagctctgactccctgtgattaccctcactatgtataaaga aaagaagtttggcattacagagcttacttataaaaaggaacccaaactcgggcatttcatagcagcatgattctgagcac acgtgggtaagacctttcttctctggttagatatcatatgctggtgtataattagcttaaatgattgtgatttagacacc taggaaataatcaatagggcaattgctttccataatactttatcttcttgtgctttatttctgaagcagagtagaatgct aaagatgtatcctagtgacagcataaaccctagaggtgacagtctgtattattgcttttcgcttctcttttctgcttctg ttgggagccagttttcttcttacgccgcattacagagagaacgtcaaatttagcaagccatatctgccataggtccaaat aaagagacaataaaaattattctctcttttttggatggaatactgcgtgaaatggttatccatacaaagatactttatgt agaatagaaaaaggaggccgggtgcagtggctcacacatgtaatcctagtgctttgggaggctaagccgggagcactgat tgaggccaggagttcatgatcagcctgggcaatgaagtgagaccccgtctctacaaaaaaatatgaaaaaattagcgagg tgtggtgacacatgcctgtagtcccagctactcaagaggctgaggtagaggatcacttgagcctacgagttcaaggctgc agtgagctatgataactccactgcactgctgcctggatgacacagagagaccgtttctaaattaattaattaacaatttt aagaaagaaaaagggccattgcttatttttccatacaaaagtaaaataaatcataatggccaataagccaatgtaacttt tttttttaagggaaagcaaaacttgtaaaacctaaaatctcttagagttttggcatttacccaaatgttttcagtgattc tgagaattggtggatataaaacacatttctcagcaaacactttcttcattttgcatcccttactgtactttcttgtactg aatctttgcttgaccagggaacccacctagcccaacaagaacaatccattctacttcttggaactacgtttattttcctt ttcccccatttcctataagataacctctaaccaatgacaatctcgacagctattcctgcaccaactgacctgaagttcac tcaggtcacacccacaagcctgagcgcccagtggacaccacccaatgttcagctcactggatatcgagtgcgggtgaccc ccaaggagaagaccggaccaatgaaagaagtcaaccttgctcctgacagctcatccgtggttgtatcaggacttatcctg cacttttgataacctgagtcccggcctggagtacaatgtcagtgtttacactgtcaaggatgacaaggaaagtgtcccta tctctgataccatcatcccaggtaatagaaaataagctgctatcctgagagtgacattccaataagagtggggattagca tcttaatccccagatgcttaagggtgtcaactatatttgggatttaattccgatctcccagctgcactttccaaaaccaa gaagtcaaagcagcgatttggacaaaatgcttgctgttaacactgctttactgtctgtgcttcactgggatgctgtgtgt tgcagcgagtatgtaatggagtggcagccatggctttaactctgtattgtctgctcacatggaagtatgactaaaacact gtcacgtgtctgtactcagtactgataggctcaaagtaatatggtaaatgcatcccatcagtacatttctgcccgatttt acaatccatatcaatttccaacagctgcctatttcatcttgcagtttcaaatccttctttttgaaaattggattttaaaa aaaagttaagtaaaagtcacaccttcagggttgttctttcttgtggccttgaaagacaacattgcaaaggcctgtcctaa ggataggcttgtttgtccattgggttataacataatgaaagcattggacagatcgtgtccccctttggactcttcagtag aatgcttttactaacgctaattacatgttttgattatgaatgaacctaaaatagtggcaatggccttaacctaggcctgt ctttcctcagcctgaatgtgcttttgaatggcacatttcacaccatacattcataatgcattagcgttatggccatgatg ttgtcatgagttttgtatgggagaaaaaaaatcaatttatcacccatttattattttttccggttgttcatgcaagctta ttttctactaaaacagttttggaattattaaaagcattgctgatacttacttcagatattatgtctaggctctaagaatg gtttcgacatcctaaacagccatatgatttttaggaatctgaacagttcaaattgtaccctttaaggatgttttcaaaat gtaaaaaatatatatatatatatatattccctaaaagaatattcctgtttattcttctagggaagcaaactgttcatgat gcttaggaagtcttttcagagaatttaaaacagattgcatattaccatcattgctttaacattccaccaattttactact agtaacctgatatacactgctttattttttcctctttttttccctctattttccttttgcctccccctccctttgctttg taactcaatagaggtgccccaactcactgacctaagctttgttgatataaccgattcaagcatcggcctgaggtggaccc cgctaaactcttccaccattattgggtaccgcatcacagtagttgcggcaggagaaggtatccctatttttgaagatttt gtggactcctcagtaggatactacacagtcacagggctggagccgggcattgactatgatatcagcgttatcactctcat taatggcggcgagagtgcccctactacactgacacaacaaacgggtgaattttgaaaacttctgcgtttgagacatagat ggtgttgcatgctgccaccagttactccggttaaatatggatgtttcatgggggaagtcagcaattggccaaagattcag ataggtggaattggggggataaggaatcaaatgcatctgctaaactgattggagaaaaacacatgcaatatcttcagtac actctcatttaaaccacaagtagatataaagcctagagaaatacagatgtctgctctgttaaatataaaatagcaaatgt tcattcaatttgaagacctagaatttttcttcttaaataccaaacacgaataccaaattgcgtaagtaccaattgataag aatatatcaccaaaatgtaccatcatgctcttccttctaccctttgataaactctaccatgctccttctttgtagctaaa aacccatcaaaatttagggtagagtggatgggcattgttttgaggtaggagaaaagtaaacttgggaccattctaggttt tgttgctgtcactaggtaaagaaacacctctttaaccacagtctggggacaagcatgcaacattttaaaggttctctgct gtgcatgggaaaagaaacatgctgagaaccaatttgcatgaacatgttcacttgtaagtagaattcactgaatggaactg tagctctagatatctcacatggggggaagtttaggaccctcttgtctttttgtctgtgtgcatgtatttctttgtaaagt actgctatgtttctctttgctgtgtggcaacttaagcctcttcggcctgggataaaataatctgcagtggtattaataat gtacataaagtcaacatatttgaaagtagattaaaatcttttttaaatatatcaatgatggcaaaaaggttaaagggggc ctaacagtactgtgtgtagtgttttatttttaacagtagtacactataacttaaaatagacttagattagactgtttgca tgattatgattctgtttcctttatgcatgaaatattgattttacctttccagctacttcgttagctttaattttaaaata cattaactgagtcttccttcttgttcgaaaccagctgttcctcctcccactgacctgcgattcaccaacattggtccaga caccatgcgtgtcacctggggaagagcaagaggcaggctcagcaaatggttcagccccagtccccggtggctgtcagtca aagcaagcccggttgttatgacaatggaaaacactatcagataaatcaacagtgggagcggacctacctaggtaatgtgt tggtttgtacttgttatggaggaagccgaggttttaactgcgaaagtaaacctgaagctgaagagacttgctttgacaag tacactgggaacacttaccgagtgggtgacacttatgagcgtcctaaagactccatgatctgggactgtacctgcatcgg ggctgggcgagggagaataagctgtaccatcgcaaaccgctgccatgaagggggtcagtcctacaagattggtgacacct ggaggagaccacatgagactggtggttacatgttagagtgtgtgtgtcttggtaatggaaaaggagaatggacctgcaag cccatagctgagaagtgttttgatcatgctgctgggacttcctatgtggtcggagaaacgtgggagaagccctaccaagg ctggatgatggtagattgtacttgcctgggagaaggcagcggacgcatcacttgcacttctagaaatagatgcaacgatc aggacacaaggacatcctatagaattggagacacctggagcaagaaggataatcgaggaaacctgctccagtgcatctgc acaggcaacggccgaggagagtggaagtgtgagaggcacacctctgtgcagaccacatcgagcggatctggccccttcac cgatgttcgtgcagctgtttaccaaccgcagcctcacccccagcctcctccctatggccactgtgtcacagacagtggtg tggtctactctgtggggatgcagtggttgaagacacaaggaaataagcaaatgctttgcacgtgcctgggcaacggagtc agctgccaagagacagctgtaacccagacttacggtggcaacttaaatggagagccatgtgtcttaccattcacctacaa tggcaggacgttctactcctgcaccacggaagggcgacaggacggacatctttggtgcagcacaacttcgaattatgagc aggaccagaaatactctttctgcacagaccacactgttttggttcagactcaaggaggaaattccaatggtgccttgtgc cacttccccttcctatacaacaaccacaattacactgattgcacttctgagggcagaagagacaacatgaagtggtgtgg gaccacacagaactatgatgccgaccagaagtttgggttctgccccatggctgcccacgaggaaatctgcacaaccaatg aaggggtcatgtaccgcattggagatcagtgggataagcagcatgacatgggtcacatgatgaggtgcacgtgtgttggg aatggtcgtggggaatggacatgcattgcctactcgcaacttcgagatcagtgcattgttgatgacatcacttacaatgt gaacgacacattccacaagcgtcatgaagaggggcacatgctgaactgtacatgcttcggtcagggtcggggcaggtgga agtgtgatcccgtcgaccaatgccaggattcagagactgggacgttttatcaaattggagattcatgggagaagtatgtg catggtgtcagataccagtgctactgctatggccgtggcattggggagtggcattgccaacctttacagacctatccaag ctcaagtggtcctgtcgaagtatttatcactgagactccgagtcagcccaactcccaccccatccagtggaatgcaccac agccatctcacatttccaagtacattctcaggtggagacctaaaaattctgtaggccgttggaaggaagctaccatacca ggccacttaaactcctacaccatcaaaggcctgaagcctggtgtggtatacgagggccagctcatcagcatccagcagta cggccaccaagaagtgactcgctttgacttcaccaccaccagcaccagcacacctgtgaccagcaacaccgtgacaggag agacgactcccttttctcctcttgtggccacttctgaatctgtgaccgaaatcacagccagtagctttgtggtctcctgg gtctcagcttccgacaccgtgtcgggattccgggtggaatatgagctgagtgaggagggagatgagccacagtacctgga tcttccaagcacagccacttctgtgaacatccctgacctgcttcctggccgaaaatacattgtaaatgtctatcagatat ctgaggatggggagcagagtttgatcctgtctacttcacaaacaacagcgcctgatgcccctcctgacccgactgtggac caagttgatgacacctcaattgttgttcgctggagcagaccccaggctcccatcacagggtacagaatagtctattcgcc atcagtagaaggtagcagcacagaactcaaccttcctgaaactgcaaactccgtcaccctcagtgacttgcaacctggtg ttcagtataacatcactatctatgctgtggaagaaaatcaagaaagtacacctgttgtcattcaacaagaaaccactggc accccacgctcagatacagtgccctctcccagggacctgcagtttgtggaagtgacagacgtgaaggtcaccatcatgtg gacaccgcctgagagtgcagtgaccggctaccgtgtggatgtgatccccgtcaacctgcctggcgagcacgggcagaggc tgcccatcagcaggaacacctttgcagaagtcaccgggctgtcccctggggtcacctattacttcaaagtctttgcagtg agccatgggagggagagcaagcctctgactgctcaacagacaaccaaactggatgctcccactaacctccagtttgtcaa tgaaactgattctactgtcctggtgagatggactccacctcgggcccagataacaggataccgactgaccgtgggcctta cccgaagaggccagcccaggcagtacaatgtgggtccctctgtctccaagtaccccctgaggaatctgcagcctgcatct gagtacaccgtatccctcgtggccataaagggcaaccaagagagccccaaagccactggagtctttaccacactgcagcc tgggagctctattccaccttacaacaccgaggtgactgagaccaccatcgtgatcacatggacgcctgctccaagaattg gttttaagctgggtgtacgaccaagccagggaggagaggcaccacgagaagtgacttcagactcaggaagcatcgttgtg tccggcttgactccaggagtagaatacgtctacaccatccaagtcctgagagatggacaggaaagagatgcgccaattgt aaacaaagtggtgacaccattgtctccaccaacaaacttgcatctggaggcaaaccctgacactggagtgctcacagtct cctgggagaggagcaccaccccagacattactggttatagaattaccacaacccctacaaacggccagcagggaaattct ttggaagaagtggtccatgctgatcagagctcctgcacttttgataacctgagtcccggcctggagtacaatgtcagtgt ttacactgtcaaggatgacaaggaaagtgtccctatctctgataccatcatcccagctgttcctcctcccactgacctgc gattcaccaacattggtccagacaccatgcgtgtcacctgggctccacccccatccattgatttaaccaacttcctggtg cgttactcacctgtgaaaaatgaggaagatgttgcagagttgtcaatttctccttcagacaatgcagtggtcttaacaaa tctcctgcctggtacagaatatgtagtgagtgtctccagtgtctacgaacaacatgagagcacacctcttagaggaagac agaaaacaggtcttgattccccaactggcattgacttttctgatattactgccaactcttttactgtgcactggattgct cctcgagccaccatcactggctacaggatccgccatcatcccgagcacttcagtgggagacctcgagaagatcgggtgcc ccactctcggaattccatcaccctcaccaacctcactccaggcacagagtatgtggtcagcatcgttgctcttaatggca gagaggaaagtcccttattgattggccaacaatcaacagtttctgatgttccgagggacctggaagttgttgctgcgacc cccaccagcctactgatcagctgggatgctcctgctgtcacagtgagatattacaggatcacttacggagaaacaggagg aaatagccctgtccaggagttcactgtgcctgggagcaagtctacagctaccatcagcggccttaaacctggagttgatt ataccatcactgtgtatgctgtcactggccgtggagacagccccgcaagcagcaagccaatttccattaattaccgaaca gaaattgacaaaccatcccagatgcaagtgaccgatgttcaggacaacagcattagtgtcaagtggctgccttcaagttc ccctgttactggttacagagtaaccaccactcccaaaaatggaccaggaccaacaaaaactaaaactgcaggtccagatc aaacagaaatgactattgaaggcttgcagcccacagtggagtatgtggttagtgtctatgctcagaatccaagcggagag agtcagcctctggttcagactgcagtaaccaacattgatcgccctaaaggactggcattcactgatgtggatgtcgattc catcaaaattgcttgggaaagcccacaggggcaagtttccaggtacagggtgacctactcgagccctgaggatggaatcc atgagctattccctgcacctgatggtgaagaagacactgcagagctgcaaggcctcagaccgggttctgagtacacagtc agtgtggttgccttgcacgatgatatggagagccagcccctgattggaacccagtccacagctattcctgcaccaactga cctgaagttcactcaggtcacacccacaagcctgagcgcccagtggacaccacccaatgttcagctcactggatatcgag tgcgggtgacccccaaggagaagaccggaccaatgaaagaaatcaaccttgctcctgacagctcatccgtggttgtatca ggacttatggtggccaccaaatatgaagtgagtgtctatgctcttaaggacactttgacaagcagaccagctcagggtgt tgtcaccactctggagaatgtcagcccaccaagaagggctcgtgtgacagatgctactgagaccaccatcaccattagct ggagaaccaagactgagacgatcactggcttccaagttgatgccgttccagccaatggccagactccaatccagagaacc atcaagccagatgtcagaagctacaccatcacaggtttacaaccaggcactgactacaagatctacctgtacaccttgaa tgacaatgctcggagctcccctgtggtcatcgacgcctccactgccattgatgcaccatccaacctgcgtttcctggcca ccacacccaattccttgctggtatcatggcagccgccacgtgccaggattaccggctacatcatcaagtatgagaagcct gggtctcctcccagagaagtggtccctcggccccgccctggtgtcacagaggctactattactggcctggaaccgggaac cgaatatacaatttatgtcattgccctgaagaataatcagaagagcgagcccctgattggaaggaaaaagacagacgagc ttccccaactggtaacccttccacaccccaatcttcatggaccagagatcttggatgttccttccacagttcaaaagacc cctttcgtcacccaccctgggtatgacactggaaatggtattcagcttcctggcacttctggtcagcaacccagtgttgg gcaacaaatgatctttgaggaacatggttttaggcggaccacaccgcccacaacggccacccccataaggcataggccaa gaccatacccgccgaatgtaggacaagaagctctctctcagacaaccatctcatgggccccattccaggacacttctgag tacatcatttcatgtcatcctgttggcactgatgaagaacccttacagttcagggttcctggaacttctaccagtgccac tctgacaggcctcaccagaggtgccacctacaacatcatagtggaggcactgaaagaccagcagaggcataaggttcggg aagaggttgttaccgtgggcaactctgtcaacgaaggcttgaaccaacctacggatgactcgtgctttgacccctacaca gtttcccattatgccgttggagatgagtgggaacgaatgtctgaatcaggctttaaactgttgtgccagtgcttaggctt tggaagtggtcatttcagatgtgattcatctagatggtgccatgacaatggtgtgaactacaagattggagagaagtggg accgtcagggagaaaatggccagatgatgagctgcacatgtcttgggaacggaaaaggagaattcaagtgtgaccc cat gaggcaacgtgttacgatgatgggaagacataccacgtaggagaacagtggcagaaggaatatctcggtgccatttgctc ctgcacatgctttggaggccagcggggctggcgctgtgacaactgccgcagacctgggggtgaacccagtcccgaaggca ctactggccagtcctacaaccagtattctcagagataccatcagagaacaaacactaatgttaattgcccaattgagtgc ttcatgcctttagatgtacaggctgacagagaagattcccgagagtaaatcatctttccaatccagaggaacaagcatgt ctctctgccaagatccatctaaactggagtgatgttagcagacccagcttagagttcttctttctttcttaagccctttg ctctggaggaagttctccagcttcagctcaactcacagcttctccaagcatcaccctgggagtttcctgagggttttctc ataaatgagggctgcacattgcctgttctgcttcgaagtattcaataccgctcagtattttaaatgaagtgattctaaga tttggtttgggatcaataggaaagcatatgcagccaaccaagatgcaaatgttttgaaatgatatgaccaaaattttaag taggaaagtcacccaaacacttctgctttcacttaagtgtctggcccgcaatactgtaggaacaagcatgatcttgttac tgtgatattttaaatatccacagtactcactttttccaaatgatcctagtaattgcctagaaatatctttctcttacctg ttatttatcaatttttcccagtatttttatacggaaaaaattgtattgaaaacacttagtatgcagttgataagaggaat ttggtataattatggtgggtgattattttttatactgtatgtgccaaagctttactactgtggaaagacaactgttttaa taaaagatttacattccaca (SEQ ID NO: 12068) ctgctcctgcgcggcagctgctttagaaggtctcgagcctcctgtaccttcccagggatgaaccgggccttccctctgga aggcgagggttcgggccacagtgagcgagggccagggcggtgggcgcgcgcagagggaaaccggatcagttgagagagaa tcaagagtagcggatgaggcgcttgtggggcgcggcccggaagccctcgggcgcgggctgggagaaggagtgggcggagg cgccgcaggaggctcccggggcctggtcgggccggctgggccccgggcgcagtggaagaaagggacgggcggtgcccggt tgggcgtcctggccagctcaccttgccctggcggctcgccccgcccggcacttgggaggagcagggcagggcccgcggcc tttgcattctgggaccgcccccttccattcccgggccagcggcgagcggcagcgacggctggagccgcagctacagcatg agagccggtgccgctcctccacgcctgcggacgcgtggcgagcggaggcagcgctgcctgttcgcgccatgggggcaccg tggggctcgccgacggcggcggcgggcgggcggcgcgggtggcgccgaggccgggggctgccatggaccgtctgtgtgct ggcggccgccggcttgacgtgtacggcgctgatcacctacgcttgctgggggcagctgccgccgctgccctgggcgtcgc caaccccgtcgcgaccggtgggcgtgctgctgtggtgggagcccttcggggggcgcgatagcgccccgaggccgccccct gactgccggctgcgcttcaacatcagcggctgccgcctgctcaccgaccgcgcgtcctacggagaggctcaggccgtgct tttccaccaccgcgacctcgtgaaggggccccccgactggcccccgccctggggcatccaggcgcacactgccgaggagg tggatctgcgcgtgttggactacgaggaggcagcggcggcggcagaagccctggcgacctccagccccaggcccccgggc cagcgctgggtttggatgaacttcgagtcgccctcgcactccccggggctgcgaagcctggcaagtaacctcttcaactg gacgctctcctaccgggcggactcggacgtctttgtgccttatggctacctctaccccagaagccaccccggcgacccgc cctcaggcctggccccgccactgtccaggaaacaggggctggtggcatgggtggtgagccactgggacgagcgccaggcc cgggtccgctactaccaccaactgagccaacatgtgaccgtggacgtgttcggccggggcgggccggggcagccggtgcc cgaaattgggctcctgcacacagtggcccgctacaagttctacctggctttcgagaactcgcagcacctggattatatca ccgagaagctctggcgcaacgcgttgctcgctggggcggtgccggtggtgctgggcccagaccgtgccaactacgagcgc tttgtgccccgcggcgccttcatccacgtggacgacttcccaagtgcctcctccctggcctcgtacctgcttttcctcga ccgcaaccccgcggtctatcgccgctacttccactggcgccggagctacgctgtccacatcacctccttctgggacgagc cttggtgccgggtgtgccaggctgtacagagggctggggaccggcccaagagcatacggaacttggccagctggttcgag cggtgaagccgcgctcccctggaagcgacccaggggaggccaagttgtcagctttttgatcctctactgtgcatctcctt gactgccgcatcatgggagtaagttcttcaaacacccatttttgctctatgggaaaaaaacgatttaccaattaatatta ctcagcacagagatgggggcccggtttccatattttttgcacagctagcaattgggctccctttgctgctgatgggcatc attgtttaggggtgaaggagggggttcttcctcaccttgtaaccagtgcagaaatgaaatagcttagcggcaagaagccg ttgaggcggtttcctgaatttccccatctgccacaggccatatttgtggcccgtgcagcttccaaatctcatacacaact gttcccgattcacgtttttctggaccaaggtgaagcaaatttgtggttgtagaaggagccttgttggtggagagtggaag gactgtggctgcaggtgggactttgttgtttggattcctcacagccttggctcctgagaaaggtgaggagggcagtccaa gaggggccgctgacttctttcacaagtactatctgttcccctgtcctgtgaatggaagcaaagtgctggattgtccttgg aggaaacttaagatgaatacatgcgtgtacctcactttacataagaaatgtattcctgaaaagctgcatttaaatcaagt cccaaattcattgacttaggggagttcagtatttaatgaaaccctatggagaatttatccctttacaatgtgaatagtca tctcctaatttgtttcttctgtctttatgtttttctataacctggattttttaaatcatattaaaattacagatgtgaaa ataaagcagaagcaacctttttccctcttcccagaaaaccagtctgtgtttacagacagaagagaaggaagccatagtgt cacttccacacaattatttatttcatgtctttactggacctgaaatttaaactgcaatgccagtcctgcaggagtgctgg cattaccctctgcagaacagtgaaaggtattgcactacattatggaatcatgcaaaaaaaa (SEQ ID NO: 12069) acgcgtggcgagcggaggcagcgctgcctgttcgcgccatgggggcaccgtggggctcgccgacggcggcggcgggcggg cggcgcgggtggcgccgaggccgggggctgccatggaccgtctgtgtgctggcggccgccggcttgacgtgtacggcgct gatcacctacgcttgctgggggcagctgccgccgctgccctgggcgtcgccaaccccgtcgcgaccggtgggcgtgctgc tgtggtgggagcccttcggggggcgcgatagcgccccgaggccgccccctgactgcccgctgcgcttcaacatcagcggc tgccgcctgctcaccgaccgcgcgtcctacggagaggctcaggccgtgcttttccaccaccgcgacctcgtgaaggggcc ccccgactggcccccgccctggggcatccaggcgcacactgccgaggaggtggatctgcgcgtgttggactacgaggagg cagcggcggcggcagaagccctggcgacctccagccccaggcccccgggccagcgctgggtttggatgaacttcgagtcg ccctcgcactccccggggctgcgaagcctggcaagtaacctcttcaactggacgctctcctaccgggcggactcggacgt ctttgtgccttatggctacctctaccccagaagccaccccggcgacccgccctcaggcctggccccgccactgtccagga aacaggggctggtggcatgggtggtgagccactgggacgagcgccaggcccgggtccgctactaccaccaactgagccaa catgtgaccgtggacgtgttcggccggggcgggccggggcagccggtgcccgaaattgggctcctgcacacagtggcccg ctacaagttctacctggctttcgagaactcgcagcacctggattatatcaccgagaagctctggcgcaacgcgttgctcg ctggggcggtgccggtggtgctgggcccagaccgtgccaactacgagcgctttgtgccccgcggcgccttcatccacgtg gacgacttcccaagtgcctcctccctggcctcgtacctgcttttcctcgaccgcaaccccgcggtctatcgccgctactt ccactggcgccggagctacgctgtccacatcacctccttctgggacgagccttggtgccgggtgtgccaggctgtacaga gggctggggaccggcccaagagcatacggaacttggccagctggttcgagcggtag (SEQ ID NO: 12070) cagatactctgacccatggatcccctgggcccggccaagccacagtggtcgtggcgctgctgtctgaccacgctgctgtt tcagctgctgatggctgtgtgtttcttctcctatctgcgtgtgtctcaagacgatcccactgtgtaccctaatgggtccc gcttcccagacagcacagggacccccgcccactccatccccctgatcctgctgtggacgtggccttttaacaaacccata gctctgccccgctgctcagagatggtgcctggcacggctgactgcaacatcactgccgaccgcaaggtgtatccacaggc agacgcggtcatcgtgcaccaccgagaggtcatgtacaaccccagtgcccagctcccacgctccccgaggcggcaggggc agcgatggatctggttcagcatggagtccccaagccactgctggcagctgaaagccatggacggatacttcaatctcacc atgtcctaccgcagcgactccgacatcttcacgccctacggctggctggagccgtggtccggccagcctgcccacccacc gctcaacctctcggccaagaccgagctggtggcctgggcagtgtccaactgggggccaaactccgccagggtgcgctact accagagcctgcaggcccatctcaaggtggacgtgtacggacgctcccacaagcccctgccccagggaaccatgatggag acgctgtcccggtacaagttctatctggccttcgagaactccttgcaccccgactacatcaccgagaagctgtggaggaa cgccctggaggcctgggccgtgcccgtggtgctgggccccagcagaagcaactacgagaggttcctgccgcccgacgcct tcatccacgtggacgacttccagagccccaaggacctggcccggtacctgcaggagctggacaaggaccacgcccgctac ctgagctactttcgctggcgggagacgctgcggcctcgctccttcagctgggcactcgctttctgcaaggcctgctggaa actgcaggaggaatccaggtaccagacacgcggcatagcggcttggttcacctgagaggcccggcatggggcctgggctg ccaggg (SEQ ID Nθ:12071) aaggagcacagttccaggcggggctgagctagggcgtagctgtgatttcaggggcacctctggcggctgccgtgatttga gaatctcgggtctcttggctgactgatcctgggagactgtggatgaataatgctgggcacggccccacccggaggctgcg aggcttgggggtcctggccggggtggctctgctcgctgccctctggctcctgtggctgctggggtcagcccctcggggta ccccggcaccccagcccacgatcaccatccttgtctggcactggcccttcactgaccagcccccagagctgcccagcgac acctgcacccgctacggcatcgcccgctgccacctgagtgccaaccgaagcctgctggccagcgccgacgccgtggtctt ccaccaccgcgagctgcagacccggcggtcccacctgcccctggcccagcggccgcgagggcagccctgggtgtgggcct ccatggagtctcctagccacacccacggcctcagccacctccgaggcatcttcaactgggtgctgagctaccggcgcgac tcggacatctttgtgccctatggccgcctggagccccactgggggccctcgccaccgctgccagccaagagcagggtggc cgcctgggtggtcagcaacttccaggagcggcagctgcgtgccaggctgtaccggcagctggcgcctcatctgcgggtgg atgtctttggccgtgccaatggacggccactgtgcgccagctgcctggtgcccaccgtggcccagtaccgcttctacctg tcctttgagaactctcagcaccgcgactacattacggagaaattctggcgcaacgcactggtggctggcactgtgccagt ggtgctggggcccccacgggccacctatgaggccttcgtgccggctgacgccttcgtgcatgtggatgactttggctcag cccgagagctggcggctttcctcactggcatgaatgagagccgataccaacgcttctttgcctggcgtgacaggctccgc gtgcgactgttcaccgactggcgggaacgtttctgtgccatctgtgaccgctacccacacctaccccgcagccaagtcta tgaggaccttgagggttggtttcaggcctgagatccgctggccgggggaggtgggtgtgggtggaagggctgggtgtcga aatcaaaccaccaggcatccggcccttaccggcaagcagcgggctaacgggaggctgggcacagaggtcaggaagcaggg gtggggggtgcaggtgggcactggagcatgcagaggaggtgagagtgggagggaggtaacgggtgcctgctgcggcagac gggaggggaaaggctgccgaggaccctccccaccctgaacaaatcttgggtgggtgaaggcctggctggaagagggtgaa aggcagggcccttggggctggggggcaccccagcctgaagtttgtgggggccaaacctgggaccccgagcttcctcggta gcagaggccctgtggtccccgagacacaggcacgggtccctgccacgtccatagttctgaggtccctgtgtgtaggctgg ggcggggcccaggagaccacggggagcaaaccagcttgttctgggctcagggagggagggcggtggacaataaacgtctg agcagtgaaaaaaaaaaaaaa (SEQ ID NO: 12072) ctgctcctgcgcggcagctgctttagaaggtctcgagcctcctgtaccttcccagggatgaaccgggccttccctctgga aggcgagggttcgggccacagtgagcgagggccagggcggtgggcgcgcgcagagggaaaccggatcagttgagagagaa tcaagagtagcggatgaggcgcttgtggggcgcggcccggaagccctcgggcgcgggctgggagaaggagtgggcggagg cgccgcaggaggctcccggggcctggtcgggccggctgggccccgggcgcagtggaagaaagggacgggcggtgcccggt tgggcgtcctggccagctcaccttgccctggcggctcgccccgcccggcacttgggaggagcagggcagggcccgcggcc tttgcattctgggaccgcccccttccattcccgggccagcggcgagcggcagcgacggctggagccgcagctacagcatg agagccggtgccgctcctccacgcctgcggacgcgtggcgagcggaggcagcgctgcctgttcgcgccatgggggcaccg tggggctcgccgacggcggcggcgggcgggcggcgcgggtggcgccgaggccgggggctgccatggaccgtctgtgtgct ggcggccgccggcttgacgtgtacggcgctgatcacctacgcttgctgggggcagctgccgccgctgccctgggcgtcgc caaccccgtcgcgaccggtgggcgtgctgctgtggtgggagcccttcggggggcgcgatagcgccccgaggccgccccct gactgccggctgcgcttcaacatcagcggctgccgcctgctcaccgaccgcgcgtcctacggagaggctcaggccgtgct tttccaccaccgcgacctcgtgaaggggccccccgactggcccccgccctggggcatccaggcgcacactgccgaggagg tggatctgcgcgtgttggactacgaggaggcagcggcggcggcagaagccctggcgacctccagccccaggcccccgggc cagcgctgggtttggatgaacttcgagtcgccctcgcactccccggggctgcgaagcctggcaagtaacctcttcaactg gacgctctcctaccgggcggactcggacgtctttgtgccttatggctacctctaccccagaagccaccccggcgacccgc cctcaggcctggccccgccactgtccaggaaacaggggctggtggcatgggtggtgagccactgggacgagcgccaggcc cgggtccgctactaccaccaactgagccaacatgtgaccgtggacgtgttcggccggggcgggccggggcagccggtgcc cgaaattgggctcctgcacacagtggcccgctacaagttctacctggctttcgagaactcgcagcacctggattatatca ccgagaagctctggcgcaacgcgttgctcgctggggcggtgccggtggtgctgggcccagaccgtgccaactacgagcgc tttgtgccccgcggcgccttcatccacgtggacgacttcccaagtgcctcctccctggcctcgtacctgcttttcctcga ccgcaaccccgcggtctatcgccgctacttccactggcgccggagctacgctgtccacatcacctccttctgggacgagc cttggtgccgggtgtgccaggctgtacagagggctggggaccggcccaagagcatacggaacttggccagctggttcgag cggtgaagccgcgctcccctggaagcgacccaggggaggccaagttgtcagctttttgatcctctactgtgcatctcctt gactgccgcatcatgggagtaagttcttcaaacacccatttttgctctatgggaaaaaaacgatttaccaattaatatta ctcagcacagagatgggggcccggtttccatattttttgcacagctagcaattgggctccctttgctgctgatgggcatc attgtttaggggtgaaggagggggttcttcctcaccttgtaaccagtgcagaaatgaaatagcttagcggcaagaagccg ttgaggcggtttcctgaatttccccatctgccacaggccatatttgtggcccgtgcagcttccaaatctcatacacaact gttcccgattcacgtttttctggaccaaggtgaagcaaatttgtggttgtagaaggagccttgttggtggagagtggaag gactgtggctgcaggtgggactttgttgtttggattcctcacagccttggctcctgagaaaggtgaggagggcagtccaa gaggggccgctgacttctttcacaagtactatctgttcccctgtcctgtgaatggaagcaaagtgctggattgtccttgg aggaaacttaagatgaatacatgcgtgtacctcactttacataagaaatgtattcctgaaaagctgcatttaaatcaagt cccaaattcattgacttaggggagttcagtatttaatgaaaccctatggagaatttatccctttacaatgtgaatagtca tctccta tttgtttcttctgtctttatgtttttctataacctggattttttaaatcatattaaaattacagatgtgaaa ataaagcagaagcaacctttttccctcttcccagaaaaccagtctgtgtttacagacagaagagaaggaagccatagtgt cacttccacacaattatttatttcatgtctttactggacctgaaatttaaactgcaatgccagtcctgcaggagtgctgg cattaccctctgcagaacagtgaaaggtattgcactacattatggaatcatgcaaaaaaaaacgcgtggcgagcggaggc agcgctgcctgttcgcgccatgggggcaccgtggggctcgccgacggcggcggcgggcgggcggcgcgggtggcgccgag gccgggggctgccatggaccgtctgtgtgctggcggccgccggcttgacgtgtacggcgctgatcacctacgcttgctgg gggcagctgccgccgctgccctgggcgtcgccaaccccgtcgcgaccggtgggcgtgctgctgtggtgggagcccttcgg ggggcgcgatagcgccccgaggccgccccctgactgcccgctgcgcttcaacatcagcggctgccgcctgctcaccgacc gcgcgtcctacggagaggctcaggccgtgcttttccaccaccgcgacctcgtgaaggggccccccgactggcccccgccc tggggcatccaggcgcacactgccgaggaggtggatctgcgcgtgttggactacgaggaggcagcggcggcggcagaagc cctggcgacctccagccccaggcccccgggccagcgctgggtttggatgaacttcgagtcgccctcgcactccccggggc tgcgaagcctggcaagtaacctcttcaactggacgctctcctaccgggcggactcggacgtctttgtgccttatggctac ctctaccccagaagccaccccggcgacccgccctcaggcctggccccgccactgtccaggaaacaggggctggtggcatg ggtggtgagccactgggacgagcgccaggcccgggtccgctactaccaccaactgagccaacatgtgaccgtggacgtgt tcggccggggcgggccggggcagccggtgcccgaaattgggctcctgcacacagtggcccgctacaagttctacctggct ttcgagaactcgcagcacctggattatatcaccgagaagctctggcgcaacgcgttgctcgctggggcggtgccggtggt gctgggcccagaccgtgccaactacgagcgctttgtgccccgcggcgccttcatccacgtggacgacttcccaagtgcct cctccctggcctcgtacctgcttttcctcgaccgcaaccccgcggtctatcgccgctacttccactggcgccggagctac gctgtccacatcacctccttctgggacgagccttggtgccgggtgtgccaggctgtacagagggctggggaccggcccaa gagcatacggaacttggccagctggttcgagcggtagcagatactctgacccatggatcccctgggcccggccaagccac agtggtcgtggcgctgctgtctgaccacgctgctgtttcagctgctgatggctgtgtgtttcttctcctatctgcgtgtg tctcaagacgatcccactgtgtaccctaatgggtcccgcttcccagacagcacagggacccccgcccactccatccccct gatcctgctgtggacgtggccttttaacaaacccatagctctgccccgctgctcagagatggtgcctggcacggctgact gcaacatcactgccgaccgcaaggtgtatccacaggcagacgcggtcatcgtgcaccaccgagaggtcatgtacaacccc agtgcccagctcccacgctccccgaggcggcaggggcagcgatggatctggttcagcatggagtccccaagccactgctg gcagctgaaagccatggacggatacttcaatctcaccatgtcctaccgcagcgactccgacatcttcacgccctacggct ggctggagccgtggtccggccagcctgcccacccaccgctcaacctctcggccaagaccgagctggtggcctgggcagtg tccaactgggggccaaactccgccagggtgcgctactaccagagcctgcaggcccatctcaaggtggacgtgtacggacg ctcccacaagcccctgccccagggaaccatgatggagacgctgtcccggtacaagttctatctggccttcgagaactcct tgcaccccgactacatcaccgagaagctgtggaggaacgccctggaggcctgggccgtgcccgtggtgctgggccccagc agaagcaactacgagaggttcctgccgcccgacgccttcatccacgtggacgacttccagagccccaaggacctggcccg gtacctgcaggagctggacaaggaccacgcccgctacctgagctactttcgctggcgggagacgctgcggcctcgctcct tcagctgggcactcgctttctgcaaggcctgctggaaactgcaggaggaatccaggtaccagacacgcggcatagcggct tggttcacctgagaggcccggcatggggcctgggctgccagggaaggagcacagttccaggcggggctgagctagggcgt agctgtgatttcaggggcacctctggcggctgccgtgatttgagaatctcgggtctcttggctgactgatcctgggagac tgtggatgaataatgctgggcacggccccacccggaggctgcgaggcttgggggtcctggccggggtggctctgctcgct gccctctggctcctgtggctgctggggtcagcccctcggggtaccccggcaccccagcccacgatcaccatccttgtctg gcactggcccttcactgaccagcccccagagctgcccagcgacacctgcacccgctacggcatcgcccgctgccacctga gtgccaaccgaagcctgctggccagcgccgacgccgtggtcttccaccaccgcgagctgcagacccggcggtcccacctg cccctggcccagcggccgcgagggcagccctgggtgtgggcctccatggagtctcctagccacacccacggcctcagcca cctccgaggcatcttcaactgggtgctgagctaccggcgcgactcggacatctttgtgccctatggccgcctggagcccc actgggggccctcgccaccgctgccagccaagagcagggtggccgcctgggtggtcagcaacttccaggagcggcagctg cgtgccaggctgtaccggcagctggcgcctcatctgcgggtggatgtctttggccgtgccaatggacggccactgtgcgc cagctgcctggtgcccaccgtggcccagtaccgcttctacctgtcctttgagaactctcagcaccgcgactacattacgg agaaattctggcgcaacgcactggtggctggcactgtgccagtggtgctggggcccccacgggccacctatgaggccttc gtgccggctgacgccttcgtgcatgtggatgactttggctcagcccgagagctggcggctttcctcactggcatgaatga gagccgataccaacgcttctttgcctggcgtgacaggctccgcgtgcgactgttcaccgactggcgggaacgtttctgtg ccatctgtgaccgctacccacacctaccccgcagccaagtctatgaggaccttgagggttggtttcaggcctgagatccg ctggccgggggaggtgggtgtgggtggaagggctgggtgtcgaaatcaaaccaccaggcatccggcccttaccggcaagc agcgggctaacgggaggctgggcacagaggtcaggaagcaggggtggggggtgcaggtgggcactggagcatgcagagga ggtgagagtgggagggaggtaacgggtgcctgctgcggcagacgggaggggaaaggctgccgaggaccctccccaccctg aacaaatcttgggtgggtgaaggcctggctggaagagggtgaaaggcagggcccttggggctggggggcaccccagcctg aagtttgtgggggccaaacctgggaccccgagcttcctcggtagcagaggccctgtggtccccgagacacaggcacgggt ccctgccacgtccatagttctgaggtccctgtgtgtaggctggggcggggcccaggagaccacggggagcaaaccagctt gttctgggctcagggagggagggcggtggacaataaacgtctgagcagtgaaaaaaaaaaaaaa (SEQ ID NO: 12073) cccccctccaagataatttttaaaaaaccttctcctttgctcacctttgcttcccagccttcccatccccccaccgaaag caaatcattcaacgacccccgaccctccgacggcaggagccccccgacctcccaggcggaccgccctccctccccggggt tccgggcccggcgagagggcgcgagcacagccgaggccatggaggtgacggcggaccagccgcgctgggtgagccaccac caccccgccgtgctcaacgggcagcacccggacacgcaccacccgggcctcagccactcctacatggacgcggcgcagta cccgctgccggaggaggtggatgtgctttttaacatcgacggtcaaggcaaccacgtcccgccctactacggaaactcgg tcagggccacggtgcagaggtaccctccgacccaccacgggagccaggtgtgccgcccgcctctgcttcatggatcccta ccctggctggacggcggcaaagccctgggcagccaccacaccgcctccccctggaatctcagccccttctccaagacgtc catccaccacggctccccggggcccctctccgtctaccccccggcctcgtcctcctccttgtcggggggccacgccagcc cgcacctcttcaccttcccgcccaccccgccgaaggacgtctccccggacccatcgctgtccaccccaggctcggccggc tcggcccggcaggacgagaaagagtgcctcaagtaccaggtgcccctgcccgacagcatgaagctggagtcgtcccactc ccgtggcagcatgaccgccctgggtggagcctcctcgtcgacccaccaccccatcaccacctacccgccctacgtgcccg agtacagctccggactcttcccccccagcagcctgctgggcggctcccccaccggcttcggatgcaagtccaggcccaag gcccggtccagcacagaaggcagggagtgtgtgaactgtggggcaacctcgaccccactgtggcggcgagatggcacggg acactacctgtgcaacgcctgcgggctctatcacaaaatgaacggacagaaccggcccctcattaagcccaagcgaaggc tgtctgcagccaggagagcagggacgtcctgtgcgaactgtcagaccaccacaaccacactctggaggaggaatgccaat ggggaccctgtctgcaatgcctgtgggctctactacaagcttcacaatattaacagacccctgactatgaagaaggaagg catccagaccagaaaccgaaaaatgtctagcaaatccaaaaagtgcaaaaaagtgcatgactcactggaggacttcccca agaacagctcgtttaacccggccgccctctccagacacatgtcctccctgagccacatctcgcccttcagccactccagc cacatgctgaccacgcccacgccgatgcacccgccatccagcctgtcctttggaccacaccacccctccagcatggtcac cgccatgggttagagccctgctcgatgctcacagggcccccagcgagagtccctgcagtccctttcgacttgcatttttg caggagcagtatcatgaagcctaaacgcgatggatatatgtttttgaaggcagaaagcaaaattatgtttgccactttgc aaaggagctcactgtggtgtctgtgttccaaccactgaatctggaccccatctgtgaataagccattctgactcatatcc cctatttaacagggtctctagtgctgtgaaaaaaaaaatgctgaacattgcatataacttatattgtaagaaatactgta caatgactttattgcatctgggtagctgtaaggcatgaaggatgccaagaagtttaaggaatatgggagaaatggtgtgg aaattaagaagaaactaggtctgatattcaaatggacaaactgccagttttgtttcctttcactggccacagttgtttga tgcattaaaagaaaataaaaaaaag (SEQ ID NO: 12074) acacagagagaaaggctaaagttctctggaggatgtggctgcagagcctgctgctcttgggcactgtggcctgcagcatc tctgcacccgcccgctcgcccagccccagcacgcagccctgggagcatgtgaatgccatccaggaggcccggcgtctcct gaacctgagtagagacactgctgctgagatgaatgaaacagtagaagtcatctcagaaatgtttgacctccaggagccga cctgcctacagacccgcctggagctgtacaagcagggcctgcggggcagcctcaccaagctcaagggccccttgaccatg atggccagccactacaagcagcactgccctccaaccccggaaacttcctgtgcaacccagattatcacctttgaaagttt caaagagaacctgaaggactttctgcttgtcatcccctttgactgctgggagccagtccaggagtgagaccggccagatg aggctggccaagccggggagctgctctctcatgaaacaagagctagaaactcaggatggtcatcttggagggaccaaggg gtgggccacagccatggtgggagtggcctggacctgccctgggcacactgaccctgatacaggcatggcagaagaatggg aatattttatactgacagaaatcagtaatatttatatatttatatttttaaaatatttatttatttatttatttaagttc atattccatatttattcaagatgttttaccgtaataattattattaaaaatagcttctaaaaaaaaaaa (SEQ ID NO: 12075) ttctctctgaccagcaccatgcttctcctggtgacaagccttctgctctgtgagttaccacacccagcattcctcctgat cccagagaaatcggatctgcgaacagtggcaccagcctctagtctcaatgtgaggtttgactccaggacgatgaatttaa gctgggactgccaagaaaacacaaccttcagcaagtgtttcttaactgacaagaagaacagagtcgtggaacccaggctc agtaacaacgaatgttcgtgcacatttcgtgaaatttgtctgcatgaaggagtcacatttgaggttcacgtgaatactag tcaaagaggatttcaacagaaactgctttatccaaattcaggaagggagggtaccgctgctcagaatttctcctgtttca tctacaatgcggatttaatgaactgtacctgggcgaggggtccgacggccccccgtgacgtccagtattttttgtacata cgaaactcaaagagaaggagggagatccggtgtccttattacatacaagactcaggaacccatgtgggatgtcacctgga taacctgtcaggattaacgtctcgcaattactttctggttaacggaaccagccgagaaattggcatccaattctttgatt cacttttggacacaaagaaaatagaacgattcaaccctcccagcaatgtcaccgtacgttgcaacacgacgcactgcctc gtacggtggaaacagcccaggacctatcagaagctgtcgtacctggactttcagtaccagctggacgtccacagaaagaa tacccagcctggcacggaaaacctactgattaatgtttctggtgatttggaaaatagatacaactttccaagctctgagc ccagagcaaaacacagtgtgaagatcagagctgcagacgtccgcatcttgaattggagctcctggagtgaagccattgaa tttggttccttaggatacagcggctgttcccgccagttccacagatcaaagacaaactgaatgataaccatgaggtggaa gacgagatcatctgggaggaattcaccccagaggaagggaaaggctaccgcgaagaggtcttgaccgtgaaggaaattac ctgagacccagagggtgtaggaatggcatggacatctccgcctccgcgacacgggggaactgttttcttgatgatgctgt gaacctttatatcattttctatgtttttatttaaaaacatgacatttggggccaggcgcggtggctcacgcctgtaatcc cag (SEQ ID NO:12076) ttctcagagtggctgcagtctcgctgctggatgtgcacatggtggtcattccctctgctcacaggggcaggggtcccccc ttactggactgaggttgccccctgctccaggtcctgggtgggagcccatgtgaactgtcagtggggcaggtctgtgagag ctcccctcacactcaagtctctctcacagtggccagagaagaggaaggctggagtcagaatgaggcaccagggcgggcat agcctgcccaaaggcccctgggattacaggcaggatggggagccctatctaagtgtctcccacgccccaccccagccatt ccaggccaggaagtccaaactgtgcccctcagagggagggggcagcctcaggcccattcagactgcccagggagggctgg agagccctcaggaaggcgggtgggtgggctgtcggttcttggaaaggttcattaatgaaaacccccaagcctgaccacct agggaaaaggctcaccgttcccatgtgtggctgataagggccaggagattccacagttcaggtagttcccccgcctccct ggcattttgtggtcaccattaatcatttcctctgtgtatttaagagctcttttgccagtgagcccagctacacagagaga aaggctaaagttctctggaggatgtggctgcagagcctgctgctcttgggcactgtggcctgcagcatctctgcacccgc ccgctcgcccagccccagcacgcagccctgggagcatgtgaatgccatccaggaggcccggcgtctcctgaacctgagta gagacactgctgctgagatggtaagtgagagaatgtgggcctgtgctaggcaccagtggccctgactggccacgcctgtc agcttgataacatgacattttccttttctacagaatgaaacagtagaagtcatctcagaaatgtttgacctccaggtaag atgcttctctctgacatagctttccagaagcccctgccctggggtggaggtggggactccattttagatggcaccacaca gggttgtccactttctctccagtcagctggctgcaggaggagggggtagcaactgggtgctcaagaggctgctggccgtg cccctatggcagtcacatgagctcctttatcagctgagcggccatgggcagacctagcattcaatggccaggag caeca ggggacaggtggtaaagtgggggtcacttcatgagacaggagctgtgggtttggggcgctcactgtgccccgagaccaag tcctgttgagacagtgctgactacagagaggcacagaggggtttcaggaacaacccttgcccacccagcaggtccaggtg aggccccacccccctctccctgaatgatggggtgagagtcacctccttccctaaggctgggctcctctccaggtgccgct gagggtggcctgggcggggcagtgagaagggcaggttcgtgcctgccatggacagggcagggtctatgactggacccagc ctgtgcccctcccaagccctactcctgggggctgggggcagcagcaaaaaggagtggtggagagttcttgtaccactgtg ggcacttggccactgctcaccgacgaacgacattttccacaggagccgacctgcctacagacccgcctggagctgtacaa gcagggcctgcggggcagcctcaccaagctcaagggccccttgaccatgatggccagccactacaagcagcactgccctc caaccccggtgagtgcctacggcagggcctccagcaggaatgtcttaatctagggggtggggtcgacatggggagagatc tatggctgtggctgttcaggaccccagggggtttctgtgccaacagttatgtaatgattagccctccagagaggaggcag acagcccatttca cccaaggagtcagagccacagagcgctgaagcccacagtgctccccagcaggagctgctcctatcc tggtcattattgtcattacggttaatgaggtcagaggtgagggcaaacccaaggaaacttggggcctgcccaaggcccag aggaagtgcccaggcccaagtgccaccttctggcaggactttcctctggccccacatggggtgcttgaattgcagaggat caaggaagggaggctacttggaatggacaaggacctcaggcactccttcctgcgggaagggagcaaagtttgtggccttg actccactccttctgggtgcccagagacgacctcagcccagctgccctgctctgccctgggaccaaaaaggcaggcgttt gactgcccagaaggccaacctcaggctggcacttaagtcaggcccttgactctggctgccactggcagagctatgcactc cttggggaacacgtgggtggcagcagcgtcacctgacccaggtcagtgggtgtgtcctggagtgggcctcctggcctctg agttctaagaggcagtagagaaacatgctggtgcttccttcccccacgttacccacttgcctggactcaagtgtttttta tttttctttttttaaaggaaacttcctgtgcaacccagattatcacctttgaaagtttcaaagagaacctgaaggacttt ctgcttgtcatcccctttgactgctgggagccagtccaggagtgagaccggccagatgaggctggccaagccggggagct gctctctcatgaaacaagagctagaaactcaggatggtcatcttggagggaccaaggggtgggccacagccatggtggga gtggcctggacctgccctgggcacactgaccctgatacaggcatggcagaagaatgggaatattttatactgacagaaat cagtaatatttatatatttatatttttaaaatatttatttatttatttatttaagttcatattccatatttattcaagat gttttaccgtaataattattattaaaaatatgcttctacttgtccagtgttctagtttgtttttaaccatgagcaaatgc cat (SEQ ID NO: 12077) acacagagagaaaggctaaagttctctggaggatgtggctgcagagcctgctgctcttgggcactgtggcctgcagcatc tctgcacccgcccgctcgcccagccccagcacgcagccctgggagcatgtgaatgccatccaggaggcccggcgtctcct gaacctgagtagagacactgctgctgagatgaatgaaacagtagaag catctcagaaatgtttgacctccaggagccga cctgcctacagacccgcctggagctgtacaagcagggcctgcggggcagcctcaccaagctcaagggccccttgaccatg atggccagccactacaagcagcactgccctccaaccccggaaacttcctgtgcaacccagattatcacctttgaaagttt caaagagaacctgaaggactttctgcttgtcatcccctttgactgctgggagccagtccaggagtgagaccggccagatg aggctggccaagccggggagctgctctctcatgaaacaagagctagaaactcaggatggtcatcttggagggaccaaggg gtgggccacagccatggtgggagtggcctggacctgccctgggcacactgaccctgatacaggcatggcagaagaatggg aatattttatactgacagaaatcagtaatatttatatatttatatttttaaaatatttatttatttatttatttaagttc atattccatatttattcaagatgttttaccgtaataattattattaaaaatagcttctaaaaaaaaaaattctctctgac cagcaccatgcttctcctggtgacaagccttctgctctgtgagttaccacacccagcattcctcctgatcccagagaaat cggatctgcgaacagtggcaccagcctctagtctcaatgtgaggtttgactccaggacgatgaatttaagctgggactgc caagaaaacacaaccttcagcaagtgtttcttaactgacaagaagaacagagtcgtggaacccaggctcagtaacaacga atgttcgtgcacatttcgtgaaatttgtctgcatgaaggagtcacatttgaggttcacgtgaatactagtcaaagaggat ttcaacagaaactgctttatccaaattcaggaagggagggtaccgctgctcagaatttctcctgtttcatctacaatgcg gatttaatgaactgtacctgggcgaggggtccgacggccccccgtgacgtccagtattttttgtacatacgaaactcaaa gagaaggagggagatccggtgtccttattacatacaagactcaggaacccatgtgggatgtcacctggataacctgtcag gattaacgtctcgcaattactttctggttaacggaaccagccgagaaattggcatccaattctttgattcacttttggac acaaagaaaatagaacgattcaaccctcccagcaatgtcaccgtacgttgcaacacgacgcactgcctcgtacggtggaa acagcccaggacctatcagaagctgtcgtacctggactttcagtaccagctggacgtccacagaaagaatacccagcctg gcacggaaaacctactgattaatgtttctggtgatttggaaaatagatacaactttccaagctctgagcccagagcaaaa cacagtgtgaagatcagagctgcagacgtccgcatcttgaattggagctcctggagtgaagccattgaatttggttcctt aggatacagcggctgttcccgccagttccacagatcaaagacaaactgaatgataaccatgaggtggaagacgagatcat ctgggaggaattcaccccagaggaagggaaaggctaccgcgaagaggtcttgaccgtgaaggaaattacctgagacccag agggtgtaggaatggcatggacatctccgcctccgcgacacgggggaactgttttcttgatgatgctgtgaacctttata tcattttctatgtttttatttaaaaacatgacatttggggccaggcgcggtggctcacgcctgtaatcccagttctcaga gtggctgcagtctcgctgctggatgtgcacatggtggtcattccctctgctcacaggggcaggggtccccccttactgga ctgaggttgccccctgctccaggtcctgggtgggagcccatgtgaactgtcagtggggcaggtctgtgagagctcccctc acactcaagtctctctcacagtggccagagaagaggaaggctggagtcagaatgaggcaccagggcgggcatagcctgcc caaaggcccctgggattacaggcaggatggggagccctatctaagtgtctcccacgccccaccccagccattccaggcca ggaagtccaaactgtgcccctcagagggagggggcagcctcaggcccattcagactgcccagggagggctggagagccct caggaaggcgggtgggtgggctgtcggttcttggaaaggttcattaatgaaaacccccaagcctgaccacctagggaaaa ggctcaccgttcccatgtgtggctgataagggccaggagattccacagttcaggtagttcccccgcctccctggcatttt gtggtcaccattaatcatttcctctgtgtatttaagagctcttttgccagtgagcccagctacacagagagaaaggctaa agttctctggaggatgtggctgcagagcctgctgctcttgggcactgtggcctgcagcatctctgcacccgcccgctcgc ccagccccagcacgcagccctgggagcatgtgaatgccatccaggaggcccggcgtctcctgaacctgagtagagacact gctgctgagatggtaagtgagagaatgtgggcctgtgctaggcaccagtggccctgactggccacgcctgtcagcttgat aacatgacattttccttttctacagaatgaaacagtagaagtcatctcagaaatgtttgacctccaggtaagatgcttct ctctgacatagctttccagaagcccctgccctggggtggaggtggggactccattttagatggcaccacacagggttgtc cactttctctccagtcagctggctgcaggaggagggggtagcaactgggtgctcaagaggctgctggccgtgcccctatg gcagtcacatgagctcctttatcagctgagcggccatgggcagacctagcattcaatggccaggagtcaccaggggacag gtggtaaagtgggggtcacttcatgagacaggagctgtgggtttggggcgctcactgtgccccgagaccaagtcctgttg agacagtgctgactacagagaggcacagaggggtttcaggaacaacccttgcccacccagcaggtccaggtgaggcccca cccccctctccctgaatgatggggtgagagtcacctccttccctaaggctgggctcctctccaggtgccgctgagggtgg cctgggcggggcagtgagaagggcaggttcgtgcctgccatggacagggcagggtctatgactggacccagcctgtgccc ctcccaagccctactcctgggggctgggggcagcagcaaaaaggagtggtggagagttcttgtaccactgtgggcacttg gccactgctcaccgacgaacgacattttccacaggagccgacctgcctacagacccgcctggagctgtacaagcagggcc tgcggggcagcctcaccaagctcaagggccccttgaccatgatggccagccactacaagcagcactgccctccaaccccg gtgagtgcctacggcagggcctccagcaggaatgtcttaatctagggggtggggtcgacatggggagagatctatggctg tggctgttcaggaccccagggggtttctgtgccaacagttatgtaatgattagccctccagagaggaggcagacagccca tttcatcccaaggagtcagagccacagagcgctgaagcccacagtgctccccagcaggagctgctcctatcctggtcatt attgtcattacggttaatgaggtcagaggtgagggcaaacccaaggaaacttggggcctgcccaaggcccagaggaagtg cccaggcccaagtgccaccttctggcaggactttcctctggccccacatggggtgcttgaattgcagaggatcaaggaag ggaggctacttggaatggacaaggacctcaggcactccttcctgcgggaagggagcaaagtttgtggccttgactccact ccttctgggtgcccagagacgacctcagcccagctgccctgctctgccctgggaccaaaaaggcaggcgtttgactgccc agaaggccaacctcaggctggcacttaagtcaggcccttgactctggctgccactggcagagctatgcactccttgggga acacgtgggtggcagcagcgtcacctgacccaggtcagtgggtgtgtcctggagtgggcctcctggcctctgagttctaa gaggcagtagagaaacatgctggtgcttccttcccccacgttacccacttgcctggactcaagtgttttttatttttctt tttttaaaggaaacttcctgtgcaacccagattatcacctttgaaagtttcaaagagaacctgaaggactttctgcttgt catcccctttgactgctgggagccagtccaggagtgagaccggccagatgaggctggccaagccggggagctgctctctc atgaaacaagagctagaaactcaggatggtcatcttggagggaccaaggggtgggccacagccatggtgggagtggcctg gacctgccctgggcacactgaccctgatacaggcatggcagaagaatgggaatattttatactgacagaaatcagtaata tttatatatttatatttttaaaatatttatttatttatttatttaagttcatattccatatttattcaagatgttttacc gtaataattattattaaaaatatgcttctacttgtccagtgttctagtttgtttttaaccatgagcaaatgccat (SEQ ID NO:12078) atcctggctgatatggtgaaaccccatctctactaaaaatacaaaaattagctgggcgtggtggtgggcgcatgtaatcc cagctactcaggaggctgaggcaggagaattacttgaacctgggaggcagaggttgcagtgaaccgagatcgcgccattg cactccagtctggcgacagagcgagactccgtctctaaataaataaataaataaatttagccttctactcaagaacttat ctggctttgtcttaatgtaaaaataatttctttttgctaaattattgagagaaatttactatttattagtgtttatcagt tttctttaaactcaccactttttgatgaatatgaaaatctaaaaacttggccgggcgcagtggctcacacctgtaatctc agcactttgggaggccaaggtgggcggatcatctgaggtcaggagttcaagatcagcctgaccaacatggtgaaacccct tctctactaaaaatacaaaaattagctgggcgtggtggtgggtgcctgtaattgtagctacttgggaggctgaggcatga gaatcacttgaacccagaaagcagaggttgcagtgagctgagatggtgccactgcactccagcctgggtgacagagtgag actctgtcctaaaaaaaaaaaaaaaaaaaatggctgggcgtggtgcctcatgcctgtaatcccagcactttgggagtcca gcgtgggtggatcacctgaggtcaggagttcaagtccagcctgaccaacatggtgaaaccccgtctctactaaaaaagta caaaaaaaatagccgggtgtggtggcacactcctgtaatcccagctactcaggaggctgaggcaggagaatcacttgaat ttgggagctggagattgtagtcagccaagatggtgccattgcactccagtctgggtgacagagtgagactccatctcaaa aaaaaaaaaaaaatcttaaaaactccttccagaagatttaatacttactttcacccaaccacccgacttgagtatcacca ataacagaggatacagtccgttttcagtagagccttagtagcaaagggttttcatttttatttttcagatacaggatctt gccctgtcacccaagctggagtgcagtgatgtgatcatagctgactgcagcctcctgagtagctaggactataggtgtat tataggacaatttttaaaaaatttcattgtaaagacaggattccactgtgttgcccaggctgcaagtcttggcctcaagt gatcattccacctttaactcttgccctcaagcagtcctcccacctcagactcccaaaatgctgggattatgggtgtgagc caccatttccagcctactagcaagggtcttgttacatattacttggcatgatttatgtaatttaaaaaaattgtttgttt ttcaaatagaaaagtaaaataacgaatatgcttttccaataacataatccccttctcacttgagaattttcctctaaaaa .gatatgctagatttatttcatgctttatgtgcctctggtgtgtccccttataacctcctccatatcatttagggatggtc tcagctgcaagtaagaactgccacaacaggtgatgtaagcccaaaaaaaaaaaaaaaaaaaaagcaaagccaagcaaaac aaagcccatttaattatttcccataataataagtctgggagaaagaagattccagagttggctcagcagcttagtgacag caaggccctaggctggcattttcttggccttcccgatggtcccaagatgactctcatggcctcaaacatcacttcctcac atcctgtcagggagaaagaggcaagtgagcaacaacaatttgtggtgtttggatcatttgtcagagaggaagaacgttcc taaaaactccgcctctgctgtttgacatcctcatcctattccttggccatggtggtatctcatggtcactcctctatctg ccactgtaaagaggaactggattgctatattctgcttagacacatgaggatgcagcccaccttcccagaacatgtgcgga attagatttctacaaacacatttgtcttgcttctgcccaactctctcactagaatgcacattccataggggcaaacattt ttgtctattttgttcacagctatattctcaacacctagaagagtgacagaaattcaataaatagttgttaagtgagcaaa tgaatgcatgaataaggaaaagggtacatggctattgagtaggtaaccagcagtgttgatcacccccaacagcatacaac tccagtctgatgaacatcatgctactaagtggccactcatcacccaagtctctgaccttactttttctctcttttctccc agggagtgagccataactggcggctgctcttgcgccaatg (SEQ ID NO: 12079) ccaatgagcctccccaattcctcctgcctcttagaagacaagatgtgtgagggcaacaagaccactatggccagccccca gctgatgcccctggtggtggtcctgagcactatctgcttggtcacagtagggctcaacctgctggtgctgtatgccgtac ggagtgagcggaagctccacactgtggggaacctgtacatcgtcagcctctcggtggcggacttgatcgtgggtgccgtc gtcatgcctatgaacatcctctacctgctcatgtccaagtggtcactgggccgtcctctctgcctcttttggctttccat ggactatgtggccagcacagcgtccattttcagtgtcttcatcctgtgcattgatcgctaccgctctgtccagcagcccc tcaggtaccttaagtatcgtaccaagacccgagcctcggccaccattctgggggcctggtttctctcttttctgtgggtt attcccattctaggctggaatcacttcatgcagcagacctcggtgcgccgagaggacaagtgtgagacagacttctatga tgtcacctggttcaaggtcatgactgccatcatcaacttctacctgcccaccttgctcatgctctggttctatgccaaga tctacaaggccgtacgacaacactgccagcaccgggagctcatcaataggtccctcccttccttctcagaaattaagctg aggccagagaaccccaagggggatgccaagaaaccagggaaggagtctccctgggaggttctgaaaaggaagccaaaaga tgctggtggtggatctgtcttgaagtcaccatcccaaacccccaaggagatgaaatccccagttgtcttcagccaagagg atgatagagaagtagacaaactctactgctttccacttgatattgtgcacatgcaggctgcggcagaggggagtagcagg gactatgtagccgtcaaccggagccatggccagctcaagacagatgagcagggcctgaacacacatggggccagcgagat atcagaggatcagatgttaggtgatagccaatccttctctcgaacggactcagataccaccacagagacagcaccaggca aaggcaaattgaggagtgggtctaacacaggcctggattacatcaagtttacttggaagaggctccgctcgcattcaaga cagtatgtatctgggttgcacatgaaccgcgaaaggaaggccgccaaacagttgggttttatcatggcagccttcatcct ctgctggatcccttatttcatcttcttcatggtcattgccttctgcaagaactgttgcaatgaacatttgcacatgttca ccatctggctgggctacatcaactccacactgaaccccctcatctaccccttgtgcaatgagaacttcaagaagacattc aagagaattctgcatattcgctcctaagggaggctctgaggggatgcaacaaaatgatccttatgatgtccaacaaggaa atagaggacgaaggcctgtgtgttgccaggcaggcacctgggctttctggaatccaaaccacagtcttaggggcttggta gtttggaaagttcttaggcaccatagaagaacagcagatggcggtgatcagcag (SEQ ID NO:12080) atgagcctccccaattcctcctgcctcttagaagacaagatgtgtgagggcaacaagaccactatggccagcccccagct gatgcccctggtggtggtcctgagcactatctgcttggtcacagtagggctcaacctgctggtgctgtatgccgtacgga gtgagcggaagctccacactgtggggaacctgtacatcgtcagcctctcggtggcggacttgatcgtgggtgccgtcgtc atgcctatgaacatcctctacctgctcatgtccaagtggtcactgggccgtcctctctgcctcttttggctttccatgga ctatgtggccagcacagcgtccattttcagtgtcttcatcctgtgcattgatcgctaccgctctgtccagcagcccctca ggtaccttaagtatcgtaccaagacccgagcctcggccaccattctgggggcctggtttctctcttttctgtgggttatt cccattctaggctggaatcacttcatgcagcagacctcggtgcgccgagaggacaagtgtgagacagacttctatgatgt cacctggttcaaggtcatgactgccatcatcaacttctacctgcccaccttgctcatgctctggttctatgccaagatct acaaggccgtacgacaacactgccagcaccgggagctcatcaataggtccctcccttccttctcagaaattaagctgagg ccagagaaccccaagggggatgccaagaaaccagggaaggagtctccctgggaggttctgaaaaggaagccaaaagatgc tggtggtggatctgtcttgaagtcaccatcccaaacccccaaggagatgaaatccccagttgtcttcagccaagaggatg atagagaagtagacaaactctactgctttccacttgatattgtgcacatgcaggctgcggcagaggggagtagcagggac tatgtagccgtcaaccggagccatggccagctcaagacagatgagcagggcctgaacacacatggggccagcgagatatc agaggatcagatgttaggtgatagccaatccttctctcgaacggactcagataccaccacagagacagcaccaggcaaag gcaaattgaggagtgggtctaacacaggcctggattacatcaagtttacttggaagaggctccgctcgcattcaagacag tatgtatctgggttgcacatgaaccgcgaaaggaaggccgccaaacagttgggttttatcatggcagccttcatcctctg ctggatcccttatttcatcttcttcatggtcattgccttctgcaagaactgttgcaatgaacatttgcacatgttcacca tctggctgggctacatcaactccacactgaaccccctcatctaccccttgtgcaatgagaacttcaagaagacattcaag agaattctgcatattcgctcctaagggaggctctgaggggatgcaacaaaatgatccttatgatgtccaacaaggaaata gaggacgaaggcctgtgtgttgccaggcaggcacctgggctttctggaatccaaaccacagtcttaggggcttggtagtt tggaaagttcttaggcaccatagaagaacagcagatggcggtgatcagcagagagattgaactttgaggaggaagcagaa tctttgcaagaaagtcagacctgtttcttgtaactgggttcaaaaagaaaaaaaaaaaaaaa (SEQ ID Nθ:12081) atcctggctgatatggtgaaaccccatctctactaaaaatacaaaaattagctgggcgtggtggtgggcgcatgtaatcc cagctactcaggaggctgaggcaggagaattacttgaacctgggaggcagaggttgcagtgaaccgagatcgcgccattg cactccagtctggcgacagagcgagactccgtctctaaataaataaataaataaatttagccttctactcaagaacttat ctggctttgtcttaatgtaaaaataatttctttttgctaaattattgagagaaatttactatttattagtgtttatcagt tttctttaaactcaccactttttgatgaatatgaaaatctaaaaacttggccgggcgcagtggctcacacctgtaatctc agcactttgggaggccaaggtgggcggatcatctgaggtcaggagttcaagatcagcctgaccaacatggtgaaacccct tct tactaaaaatacaaaaattagctgggcgtggtggtgggtgcctgtaattgtagctacttgggaggctgaggcatga gaatcacttgaacccagaaagcagaggttgcagtgagctgagatggtgccactgcactccagcctgggtgacagagtgag actctgtcctaaaaaaaaaaaaaaaaaaaatggctgggcgtggtgcctcatgcctgtaatcccagcactttgggagtcca gcgtgggtggatcacctgaggtcaggagttcaagtccagcctgaccaacatggtgaaaccccgtctctactaaaaaagta caaaaaaaatagccgggtgtggtggcacactcctgtaatcccagctactcaggaggctgaggcaggagaatcacttgaat ttgggagctggagattgtagtcagccaagatggtgccattgcactccagtctgggtgacagagtgagactccatctcaaa aaaaaaaaaaaaatcttaaaaactccttccagaagatttaatacttactttcacccaaccacccgacttgagtatcacca ataacagaggatacagtccgttttcagtagagccttagtagcaaagggttttcatttttatttttcagatacaggatctt gccctgtcacccaagctggagtgcagtgatgtgatcatagctgactgcagcctcctgagtagctaggactataggtgtat tataggacaatttttaaaaaatttcattgtaaagacaggattccactgtgttgcccaggctgcaagtcttggcctcaagt gatcattccacctttaactcttgccctcaagcagtcctcccacctcagactcccaaaatgctgggattatgggtgtgagc caccatttccagcctactagcaagggtcttgttacatattacttggcatgatttatgtaatttaaaaaaattgtttgttt ttcaaatagaaaagtaaaataacgaatatgcttttccaataacataatccccttctcacttgagaattttcctctaaaaa gatatgctagatttatttcatgctttatgtgcctctggtgtgtccccttataacctcctccatatcatttagggatggtc tcagctgcaagtaagaactgccacaacaggtgatgtaagcccaaaaaaaaaaaaaaaaaaaaagcaaagccaagcaaaac aaagcccatttaattatttcccataataataagtctgggagaaagaagattccagagttggctcagcagcttagtgacag caaggccctaggctggcattttcttggccttcccgatggtcccaagatgactctcatggcctcaaacatcacttcctcac atcctgtcagggagaaagaggcaagtgagcaacaacaatttgtggtgtttggatcatttgtcagagaggaagaacgttcc taaaaactccgcctctgctgtttgacatcctcatcctattccttggccatggtggtatctcatggtcactcctctatctg ccactgtaaagaggaactggattgctatattctgcttagacacatgaggatgcagcccaccttcccagaacatgtgcgga attagatttctacaaacacatttgtcttgcttctgcccaactctctcactagaatgcacattccataggggcaaacattt ttgtctattttgttcacagctatattctcaacacctagaagagtgacagaaattcaataaatagttgttaagtgagcaaa tgaatgcatgaataaggaaaagggtacatggctattgagtaggtaaccagcagtgttgatcacccccaacagcatacaac tccagtctgatgaacatcatgctactaagtggccactcatcacccaagtctctgaccttactttttctctcttttctccc agggagtgagccataactggcggctgctcttgcgccaatgccaatgagcctccccaattcctcctgcctcttagaagaca agatgtgtgagggcaacaagaccactatggccagcccccagctgatgcccctggtggtggtcctgagcactatctgcttg gtcacagtagggctcaacctgctggtgctgtatgccgtacggagtgagcggaagctccacactgtggggaacctgtacat cgtcagcctctcggtggcggacttgatcgtgggtgccgtcgtcatgcctatgaacatcctctacctgctcatgtccaagt ggtcactgggccgtcctctctgcctcttttggctttccatggactatgtggccagcacagcgtccattttcagtgtcttc atcctgtgcattgatcgctaccgctctgtccagcagcccctcaggtaccttaagtatcgtaccaagacccgagcctcggc caccattctgggggcctggtttctctcttttctgtgggttattcccattctaggctggaatcacttcatgcagcagacct cggtgcgccgagaggacaagtgtgagacagacttctatgatgtcacctggttcaaggtcatgactgccatcatcaacttc tacctgcccaccttgctcatgctctggttctatgccaagatctacaaggccgtacgacaacactgccagcaccgggagct catcaataggtccctcccttccttctcagaaattaagctgaggccagagaaccccaagggggatgccaagaaaccaggga aggagtctccctgggaggttctgaaaaggaagccaaaagatgctggtggtggatctgtcttgaagtcaccatcccaaacc cccaaggagatgaaatccccagttgtcttcagccaagaggatgatagagaagtagacaaactctactgctttccacttga tattgtgcacatgcaggctgcggcagaggggagtagcagggactatgtagccgtcaaccggagccatggccagctcaaga cagatgagcagggcctgaacacacatggggccagcgagatatcagaggatcagatgttaggtgatagccaatccttctct cgaacggactcagataccaccacagagacagcaccaggcaaaggcaaattgaggagtgggtctaacacaggcctggatta catcaagtttacttggaagaggctccgctcgcattcaagacagtatgtatctgggttgcacatgaaccgcgaaaggaagg ccgccaaacagttgggttttatcatggcagccttcatcctctgctggatcccttatttcatcttcttcatggtcattgcc ttctgcaagaactgttgcaatgaacatttgcacatgttcaccatctggctgggctacatcaactccacactgaaccccct catctaccccttgtgcaatgagaacttcaagaagacattcaagagaattctgcatattcgctcctaagggaggctctgag gggatgcaacaaaatgatccttatgatgtccaacaaggaaatagaggacgaaggcctgtgtgttgccaggcaggcacctg ggctttctggaatccaaaccacagtcttaggggcttggtagtttggaaagttcttaggcaccatagaagaacagcagatg gcggtgatcagcagatgagcctccccaattcctcctgcctcttagaagacaagatgtgtgagggcaacaagaccactatg gccagcccccagctgatgcccctggtggtggtcctgagcactatctgcttggtcacagtagggctcaacctgctggtgct gtatgccgtacggagtgagcggaagctccacactgtggggaacctgtacatcgtcagcctctcggtggcggacttgatcg tgggtgccgtcgtcatgcctatgaacatcctctacctgctcatgtccaagtggtcactgggccgtcctctctgcctcttt tggctttccatggactatgtggccagcacagcgtccattttcagtgtcttcatcctgtgcattgatcgctaccgctctgt ccagcagcccctcaggtaccttaagtatcgtaccaagacccgagcctcggccaccattctgggggcctggtttctctctt ttctgtgggttattcccattctaggctggaatcacttcatgcagcagacctcggtgcgccgagaggacaagtgtgagaca gacttctatgatgtcacctggttcaaggtcatgactgccatcatcaacttctacctgcccaccttgctcatgctctggtt ctatgccaagatctacaaggccgtacgacaacactgccagcaccgggagctcatcaataggtccctcccttccttctcag aaattaagctgaggccagagaaccccaagggggatgccaagaaaccagggaaggagtctccctgggaggttctgaaaagg aagccaaaagatgctggtggtggatctgtcttgaagtcaccatcccaaacccccaaggagatgaaatccccagttgtctt cagccaagaggatgatagagaagtagacaaactctactgctttccacttgatattgtgcacatgcaggctgcggcagagg ggagtagcagggactatgtagccgtcaaccggagccatggccagctcaagacagatgagcagggcctgaacacacatggg gccagcgagatatcagaggatcagatgttaggtgatagccaatccttctctcgaacggactcagataccaccacagagac agcaccaggcaaaggcaaattgaggagtgggtctaacacaggcctggattacatcaagtttacttggaagaggctccgct cgcattcaagacagtatgtatctgggttgcacatgaaccgcgaaaggaaggccgccaaacagttgggttttatcatggca gccttcatcctctgctggatcccttatttcatcttcttcatggtcattgccttctgcaagaactgttgcaatgaacattt gcacatgttcaccatctggctgggctacatcaactccacactgaaccccctcatctaccccttgtgcaatgagaacttca agaagacattcaagagaattctgcatattcgctcctaagggaggctctgaggggatgcaacaaaatgatccttatgatgt ccaacaaggaaatagaggacgaaggcctgtgtgttgccaggcaggcacctgggctttctggaatccaaaccacagtctta ggggcttggtagtttggaaagttcttaggcaccatagaagaacagcagatggcggtgatcagcagagagattgaactttg aggaggaagcagaatctttgcaagaaagtcagacctgtttcttgtaactgggttcaaaaagaaaaaaaaaaaaaaa (SEQ ID NO: 12082) cacgcgtccgcgagaaggaggactcgcaagcctcggcggcccggaaccggcctcggactgtcgacggaacctgaggccgc ttgccctcccgccccatggagcggcccccggggctgcggccgggcgcgggcgggccctgggagatgcgggagcggctggg caccggcggcttcgggaacgtctgtctgtaccagcatcgggaacttgatctcaaaatagcaattaagtcttgtcgcctag agctaagtaccaaaaacagagaacgatggtgccatgaaatccagattatgaagaagttgaaccatgccaatgttgtaaag gcctgtgatgttcctgaagaattgaatattttgattcatgatgtgcctcttctagcaatggaatactgttctggaggaga tctccgaaagctgctcaacaaaccagaaaattgttgtggacttaaagaaagccagatactttctttactaagtgatatag ggtctgggattcgatatttgcatgaaaacaaaattatacatcgagatctaaaacctgaaaacatagttcttcaggatgtt ggtggaaagataatacataaaataattgatctgggatatgccaaagatgttgatcaaggaagtctgtgtacatcttttgt gggaacactgcagtatctggccccagagctctttgagaataagccttacacagccactgttgattattggagctttggga ccatggtatttgaatgtattgctggatataggccttttttgcatcatctgcagccatttacctggcatgagaagattaag aagaaggatccaaagtgtatatttgcatgtgaagagatgtcaggagaagttcggtttagtagccatttacctcaaccaaa tagcctttgtagtttaatagtagaacccatggaaaactggctacagttgatgttgaattgggaccctcagcagagaggag gacctgttgaccttactttgaagcagccaagatgttttgtattaatggatcacattttgaatttgaagatagtacacatc ctaaatatgacttctgcaaagataatttcttttctgttaccacctgatgaaagtcttcattcactacagtctcgtattga gcgtgaaactggaataaatactggttctcaagaacttctttcagagacaggaatttctctggatcctcggaaaccagcct ctcaatgtgttctagatggagttagaggctgtgatagctatatggtttatttgtttgataaaagtaaaactgtatatgaa gggccatttgcttccagaagtttatctgattgtgtaaattatattgtacaggacagcaaaatacagcttccaattataca gctgcgtaaagtgtgggctgaagcagtgcactatgtgtctggactaaaagaagactatagcaggctctttcagggacaaa gggcagcaatgttaagtcttcttagatataatgctaacttaacaaaaatgaagaacactttgatctcagcatcacaacaa ctgaaagctaaattggagttttttcacaaaagcattcagcttgacttggagagatacagcgagcagatgacgtatgggat atcttcagaaaaaatgctaaaagcatggaaagaaatggaagaaaaggccatccactatgctgaggttggtgtcattggat acctggaggatcagattatgtctttgcatgctgaaatcatggagctacagaagagcccctatggaagacgtcagggagac ttgatggaatctctggaacagcgtgccattgatctatataagcagttaaaacacagaccttcagatcactcctacagtga cagcacagagatggtgaaaatcattgtgcacactgtgcagagtcaggaccgtgtgctcaaggagctgtttggtcatttga gcaagttgttgggctgtaagcagaagattattgatctactccctaaggtggaagtggccctcagtaatatcaaagaagct gacaatactgtcatgttcatgcagggaaaaaggcagaaagaaatatggcatctccttaaaattgcctgtacacagagttc tgcccggtcccttgtaggatccagtctagaaggtgcagtaacccctcagacatcagcatggctgcccccgacttcagcag aacatgatcattctctgtcatgtgtggtaactcctcaagatggggagacttcagcacaaatgatagaagaaaatttgaac tgccttggccatttaagcactattattcatgaggcaaatgaggaacagggcaatagtatgatgaatcttgattggagttg gttaacagaatgagttgtcacttgttcactgtccccaaacctatggaagttgttgctatacatgttggaaatgtgttttt cccccatgaaaccattcttcagacatcagtcaatggaagaaatggctatgaacagaaactacatttctactatgatcaga agaacatgattttacaagtataacagttttgagtaattcaagcctctaaacagacaggaatttagaaaaagtcaatgtac ttgtttgaatatttgttttaataccacagctatttagaagcatcatcacgacacatttgccttcagtcttggtaaaacat tacttatttaactgattaaaaataccttctatgtattagtgtcaacttttaacttttgggcgtaagacaaagtgtagttt tgtatacagagaagaaaacctcaagtaataggcattttaagtaaaagtctacctgtgtttttttctaaaaaggctgctca caagttctatttcttgaagaataaattctacctccttgtgttgcactgaacaggttctcttcctggcatcataaggagtt ggtgtaatcattttaaattccactgaaaatttaacagtatccccttctcatcgaagggattgtgtatctgtgcttctaat attagttggctttcataaatcatgttgttgtgtgtatatgtatttaagatgtacatttaataatatcaaagagaagatgc ctgttaatttataatgtatttgaaaattacatgttttttcatttgtaaaaatgagtcatttgtttaaacaatctttcatg tcttgtcatacaaatttataaaggtctgcactcctttatctgtaattgtaattccaaaatccaaaaagctctgaaaacaa ggtttccataagcttggtgacaaaattcatttgcttgcaatctaatctgaactgaccttgaatctttttatcccatttag tgtgaatattcctttattttgctgcttgatgatgagagggagggctgctgccacagactgtggtgagggctggttaatgt agtatggtatatgcacaaaactacttttctaaaatctaaaatttcataattctgaaacaacttgccccaagggtttcaga gaaaggactgtggacctctatcatctgctaagtaatttagaagatattatttgtcttaaaaaatgtgaaatgcttttata ttctaatagtttttcactttgtgtattaaatggtttttaaattaaaaaaaaaaaaaaaa (SEQ ID NO:12083) gcccgcgttaagattcccgcattttaatgttttcaggggggtgtcatagccccgggtttggccgccccagccccgccttc cccgccccggggagcccgcccccttccccgcgtccctgccgacagagttagcacgacatcagtatgagctggtcaccttc cctgacaacgcagacatgtggggcctgggaaatgaaagagcgccttgggacagggggatttggaaatgtcatccgatggc acaatcaggaaacaggtgagcagattgccatcaagcagtgccggcaggagctcagcccccggaaccgagagcggtggtgc ctggagatccagatcatgagaaggctgacccaccccaatgtggtggctgcccgagatgtccctgaggggatgcagaactt ggcgcccaatgacctgcccctgctggccatggagtactgccaaggaggagatctccggaagtacctgaaccagtttgaga actgctgtggtctgcgggaaggtgccatcctcaccttgctgagtgacattgcctctgcgcttagataccttcatgaaaac agaatcatccatcgggatctaaagccagaaaacatcgtcctgcagcaaggagaacagaggttaatacacaaaattattga cctaggatatgccaaggagctggatcagggcagtctttgcacatcattcgtggggaccctgcagtacctggccccagagc tactggagcagcagaagtacacagtgaccgtcgactactggagcttcggcaccctggcctttgagtgcatcacgggcttc cggcccttcctccccaactggcagcccgtgcagtggcattcaaaagtgcggcagaagagtgaggtggacattgttgttag cgaagacttgaatggaacggtgaagttttcaagctctttaccctaccccaataatcttaacagtgtcctggctgagcgac tggagaagtggctgcaactgatgctgatgtggcacccccgacagaggggcacggatcccacgtatgggcccaatggctgc ttcaaggccctggatgacatcttaaacttaaagctggttcatatcttgaacatggtcacgggcaccatccacacctaccc tgtgacagaggatgagagtctgcagagcttgaaggccagaatccaacaggacacgggcatcccagaggaggaccaggagc tgctgcaggaagcgggcctggcgttgatccccgataagcctgccactcagtgtatttcagacggcaagttaaatgagggc cacacattggacatggatcttgtttttctctttgacaacagtaaaatcacctatgagactcagatctccccacggcccca acctgaaagtgtcagctgtatccttcaagagcccaagaggaatctcgccttcttccagctgaggaaggtgtggggccagg tctggcacagcatccagaccctgaaggaagattgcaaccggctgcagcagggacagcgagccgccatgatgaatctcctc cgaaacaacagctgcctctccaaaatgaagaattccatggcttccatgtctcagcagctcaaggccaagttggatttctt caaaaccagcatccagattgacctggagaagtacagcgagcaaaccgagtttgggatcacatcagataaactgctgctgg cctggagggaaatggagcaggctgtggagctctgtgggcgggagaacgaagtgaaactcctggtagaacggatgatggct ctgcagaccgacattgtggacttacagaggagccccatgggccggaagcaggggggaacgctggacgacctagaggagca agcaagggagctgtacaggagactaagggaaaaacctcgagaccagcgaactgagggtgacagtcaggaaatggtacggc tgctgcttcaggcaattcagagcttcgagaagaaagtgcgagtgatctatacgcagctcagtaaaactgtggtttgcaag cagaaggcgctggaactgttgcccaaggtggaagaggtggtgagcttaatgaatgaggatgagaagactgttgtccggct gcaggagaagcggcagaaggagctctggaatctcctgaagattgcttgtagcaaggtccgtggtcctgtcagtggaagcc cggatagcatgaatgcctctcgacttagccagcctgggcagctgatgtctcagccctccacggcctccaacagcttacct gagccagccaagaagagtgaagaactggtggctgaagcacataacctctgcaccctgctagaaaatgccatacaggacac tgtgagggaacaagaccagagtttcacggccctagactggagctggttacagacggaagaagaagagcacagctgcctgg agcaggcctcatgatgtggggggactcgaccccctgacatggggcagcccatagcaggccttgtgcagtggggggactcg accccctgacatggggctgcctggagcaggccgcgtgacgtggggctgcctggccgcggctctcacatggtggttcctgc tgcactgatggcccaggggtctctggtatccagatggagctctcgcttcctcagcagctgtgactttcacccaggaccca ggacgcagccctccgtgggcactgccggcgccttgtctgcacactggaggtcctccattacagaggcccagcgcacatcg ctggccccacaaacgttcaggggtacagccatggcagctccttcctctgccgtgagaaaagtgcttggagtacggtttgc cacacacgtgactggacagtgtccaattcaaatctttcagggcagagtccgagcagcgcttggtgacagcctgtcctctc ctgctctccaaaggccctgctccctgtcctctctcactttacagcttgtgtttcttctggattcagcttctcctaaacag acagtttaattatagttgcggcctggccccatcctcacttcctctttttatttcactgctgctaaaattgtgtttttacc tacaaaaaaaaaaaaaaa (SEQ ID NO: 12084) ggcacgagcatggcccttgtgatccaggtggggaaactaaggcccagagaagtgaggaccccgcagactatcaatcccag tctcttcccctcactccctgtgaagctctccagcatcatcgaggtcccatcagcccttgccctgttggatgaataggcac ctctggaagagccaactgtgtgagatggtgcagcccagtggtggcccggcagcagatcaggacgtactgggcgaagagtc tcctctggggaagccagccatgctgcacctgccttcagaacagggcgctcctgagaccctccagcgctgcctggaggaga atcaagagctccgagatgccatccggcagagcaaccagattctgcgggagcgctgcgaggagcttctgcatttccaagcc agccagagggaggagaaggagttcctcatgtgcaagttccaggaggccaggaaactggtggagagactcggcctggagaa gctcgatctgaagaggcagaaggagcaggctctgcgggaggtggagcacctgaagagatgccagcagcagatggctgagg acaaggcctctgtgaaagcccaggtgacgtccttgctcggggagctgcaggagagccagagtcgcttggaggctgccact aaggaatgccaggctctggagggtcgggcccgggcggccagcgagcaggcgcggcagctggagagtgagcgcgaggcgct gcagcagcagcacagcgtgcaggtggaccagctgcgcatgcagggccagagcgtggaggccgcgctccgcatggagcgcc aggccgcctcggaggagaagaggaagctggcccagttgcaggtggcctatcaccagctcttccaagaatacgacaaccac atcaagagcagcgtggtgggcagtgagcggaagcgaggaatgcagctggaagatctcaaacagcagctccagcaggccga ggaggccctggtggccaaacaggaggtgatcgataagctgaaggaggaggccgagcagcacaagattgtgatggagaccg ttccggtgctgaaggcccaggcggatatctacaaggcggacttccaggctgagaggcaggcccgggagaagctggccgag aagaaggagctcctgcaggagcagctggagcagctgcagagggagtacagcaaactgaaggccagctgtcaggagtcggc caggatcgaggacatgaggaagcggcatgtcgaggtctcccaggcccccttgccccccgcccctgcctacctctcctctc ccctggccctgcccagccagaggaggagcccccccgaggagccacctgacttctgctgtcccaagtgccagtatcaggcc cctgatatggacaccctgcagatacatgtcatggagtgcattgagtagggccggccagtgcaaggccactgcctgcccga ggacgtgcccgggaccgtgcagtctgcgctttcctctcccgcctgcctagcccaggatgaagggctgggtggccacaact gggatgccacctggagccccacccaggagctggccgcggcaccttacgcttcagctgttgatccgctggtcccctctttt ggggtagatgcggccccgatcaggcctgactcgctgctctttttgttcccttctgtctgctcgaaccacttgcctcgggc taatccctccctcttcctccacccggcactggggaagtcaagaatggggcctggggctctcagggagaactgcttcccct ggcagagctgggtggcagctcttcctcccaccggacaccgacccgcccgccgctgtgccctgggagtgctgccctcttac catgcacacgggtgctctccttttgggctgcatgctattccattttgcagccagaccgatgtgtatttaaccagtcacta ttgatggacatttgggttgtttcccatctttttgttaccataaataatggcatagtaaaaaaaaaaaaaaaaaa (SEQ ID NO.-12035) cacgcgtccgcgagaaggaggactcgcaagcctcggcggcccggaaccggcctcggactgtcgacggaacctgaggccgc ttgccctcccgccccatggagcggcccccggggctgcggccgggcgcgggcgggccctgggagatgcgggagcggctggg caccggcggcttcgggaacgtctgtctgtaccagcatcgggaacttgatctcaaaatagcaattaagtcttgtcgcctag agctaagtaccaaaaacagagaacgatggtgccatgaaatccagattatgaagaagttgaaccatgccaatgttgtaaag gcctgtgatgttcctgaagaattgaatattttgattcatgatgtgcctcttc agcaatggaatactgttctggaggaga tctccgaaagctgctcaacaaaccagaaaattgttgtggacttaaagaaagccagatactttctttactaagtgatatag ggtctgggattcgatatttgcatgaaaacaaaattatacatcgagatctaaaacctgaaaacatagttcttcaggatgtt ggtggaaagataatacataaaataattgatctgggatatgccaaagatgttgatcaaggaagtctgtgtacatcttttgt gggaacactgcagtatctggccccagagctctttgagaataagccttacacagccactgttgattattggagctttggga ccatggtatttgaatgtattgctggatataggccttttttgcatcatctgcagccatttacctggcatgagaagattaag aagaaggatccaaagtgtatatttgcatgtgaagagatgtcaggagaagttcggtttagtagccatttacctcaaccaaa tagcctttgtagtttaatagtagaacccatggaaaactggctacagttgatgttgaattgggaccctcagcagagaggag gacctgttgaccttactttgaagcagccaagatgttttgtattaatggatcacattttgaatttgaagatagtacacatc ctaaatatgacttctgcaaagataatttcttttctgttaccacctgatgaaagtcttcattcactacagtctcgtattga gcgtgaaactggaataaatactggttctcaagaacttctttcagagacaggaatttctctggatcctcggaaaccagcct ctcaatgtgttctagatggagttagaggctgtgatagctatatggtttatttgtttgataaaagtaaaactgtatatgaa gggccatttgcttccagaagtttatctgattgtgtaaattatattgtacaggacagcaaaatacagcttccaattataca gctgcgtaaagtgtgggctgaagcagtgcactatgtgtctggactaaaagaagactatagcaggctctttcagggacaaa gggcagcaatgttaagtcttcttagatataatgctaacttaacaaaaatgaagaacactttgatctcagcatcacaacaa ctgaaagctaaattggagttttttcacaaaagcattcagcttgacttggagagatacagcgagcagatgacgtatgggat atcttcagaaaaaatgctaaaagcatggaaagaaatggaagaaaaggccatccactatgctgaggttggtgtcattggat acctggaggatcagattatgtctttgcatgctgaaatcatggagctacagaagagcccctatggaagacgtcagggagac ttgatggaatctctggaacagcgtgccattgatctatataagcagttaaaacacagaccttcagatcactcctacagtga cagcacagagatggtgaaaatcattgtgcacactgtgcagagtcaggaccgtgtgctcaaggagctgtttggtcatttga gcaagttgttgggctgtaagcagaagattattgatctactccctaaggtggaagtggccctcagtaatatcaaagaagct gacaatactgtcatgttcatgcagggaaaaaggcagaaagaaatatggcatctccttaaaattgcctgtacacagagttc tgcccggtcccttgtaggatccagtctagaaggtgcagtaacccctcagacatcagcatggctgcccccgacttcagcag aacatgatcattctctgtcatgtgtggtaactcctcaagatggggagacttcagcacaaatgatagaagaaaatttgaac tgccttggccatttaagcactattattcatgaggcaaatgaggaacagggcaatagtatgatgaatcttgattggagttg gttaacagaatgagttgtcacttgttcactgtccccaaacctatggaagttgttgctatacatgttggaaatgtgttttt cccccatgaaaccattcttcagacatcagtcaatggaagaaatggctatgaacagaaactacatttctactatgatcaga agaacatgattttacaagtataacagttttgagtaattcaagcctctaaacagacaggaatttagaaaaagtcaatgtac ttgtttgaatatttgttttaataccacagctatttagaagcatcatcacgacacatttgccttcagtcttggtaaaacat tacttatttaactgattaaaaataccttctatgtattagtgtcaacttttaacttttgggcgtaagacaaagtgtagttt tgtatacagagaagaaaacctcaagtaataggcattttaagtaaaagtctacctgtgtttttttctaaaaaggctgctca caagttctatttcttgaagaataaattctacctccttgtgttgcactgaacaggttctcttcctggcatcataaggagtt ggtgtaatcattttaaattccactgaaaatttaacagtatccccttctcatcgaagggattgtgtatctgtgcttctaat attagttggctttcataaatcatgttgttgtgtgtatatgtatttaagatgtacatttaataatatcaaagagaagatgc ctgttaatttataatgtatttgaaaattacatgttttttcatttgtaaaaatgagtcatttgtttaaacaatctttcatg tcttgtcatacaaatttataaaggtctgcactcctttatctgtaattgtaattccaaaatccaaaaagctctgaaaacaa ggtttccataagcttggtgacaaaattcatttgcttgcaatctaatctgaactgaccttgaatctttttatcccatttag tgtgaatattcctttattttgctgcttgatgatgagagggagggctgctgccacagactgtggtgagggctggttaatgt agtatggtatatgcacaaaactacttttctaaaatctaaaatttcataattctgaaacaacttgccccaagggtttcaga gaaaggactgtggacctctatcatctgctaagtaatttagaagatattatttgtcttaaaaaatgtgaaatgcttttata ttctaatagtttttcactttgtgtattaaatggtttttaaattaaaaaaaaaaaaaaaagcccgcgttaagattcccgca ttttaatgttttcaggggggtgtcatagccccgggtttggccgccccagccccgccttccccgccccggggagcccgccc ccttccccgcgtccctgccgacagagttagcacgacatcagtatgagctggtcaccttccctgacaacgcagacatgtgg ggcctgggaaatgaaagagcgccttgggacagggggatttggaaatgtcatccgatggcacaatcaggaaacaggtgagc agattgccatcaagcagtgccggcaggagctcagcccccggaaccgagagcggtggtgcctggagatccagatcatgaga aggctgacccaccccaatgtggtggctgcccgagatgtccctgaggggatgcagaacttggcgcccaatgacctgcccct gctggccatggagtactgccaaggaggagatctccggaagtacctgaaccagtttgagaactgctgtggtctgcgggaag gtgccatcctcaccttgctgagtgacattgcctctgcgcttagataccttcatgaaaacagaatcatccatcgggatcta aagccagaaaacatcgtcctgcagcaaggagaacagaggttaatacacaaaattattgacctaggatatgccaaggagct ggatcagggcagtctttgcacatcattcgtggggaccctgcagtacctggccccagagctactggagcagcagaagtaca cagtgaccgtcgactactggagcttcggcaccctggcctttgagtgcatcacgggcttccggcccttcctccccaactgg cagcccgtgcagtggcattcaaaagtgcggcagaagagtgaggtggacattgttgttagcgaagacttgaatggaacggt gaagttttcaagctctttaccctaccccaataatcttaacagtgtcctggctgagcgactggagaagtggctgcaactga tgctgatgtggcacccccgacagaggggcacggatcccacgtatgggcccaatggctgcttcaaggccctggatgacatc ttaaacttaaagctggttcatatcttgaacatggtcacgggcaccatccacacctaccctgtgacagaggatgagagtct gcagagcttgaaggccagaatccaacaggacacgggcatcccagaggaggaccaggagctgctgcaggaagcgggcctgg cgttgatccccgataagcctgccactcagtgtatttcagacggcaagttaaatgagggccacacattggacatggatctt gtttttctctttgacaacagtaaaatcacctatgagactcagatctccccacggccccaacctgaaagtgtcagctgtat ccttcaagagcccaagaggaatctcgccttcttccagctgaggaaggtgtggggccaggtctggcacagcatccagaccc tgaaggaagattgcaaccggctgcagcagggacagcgagccgccatgatgaatctcctccgaaacaacagctgcctctcc aaaatgaagaattccatggcttccatgtctcagcagctcaaggccaagttggatttcttcaaaaccagcatccagattga cctggagaagtacagcgagcaaaccgagtttgggatcacatcagataaactgctgctggcctggagggaaatggagcagg ctgtggagctctgtgggcgggagaacgaagtgaaactcctggtagaacggatgatggctctgcagaccgacattgtggac ttacagaggagccccatgggccggaagcaggggggaacgctggacgacctagaggagcaagcaagggagctgtacaggag actaagggaaaaacctcgagaccagcgaactgagggtgacagtcaggaaatggtacggctgctgcttcaggcaattcaga gcttcgagaagaaagtgcgagtgatctatacgcagctcagtaaaactgtggtttgcaagcagaaggcgctggaactgttg cccaaggtggaagaggtggtgagcttaatgaatgaggatgagaagactgttgtccggctgcaggagaagcggcagaagga gctctggaatctcctgaagattgcttgtagcaaggtccgtggtcctgtcagtggaagcccggatagcatgaatgcctctc gacttagccagcctgggcagctgatgtctcagccctccacggcctccaacagcttacctgagccagccaagaagagtgaa gaactggtggctgaagcacataacctctgcaccctgctagaaaatgccatacaggacactgtgagggaacaagaccagag tttcacggccctagactggagctggttacagacggaagaagaagagcacagctgcctggagcaggcctcatgatgtgggg ggactcgaccccctgacatggggcagcccatagcaggccttgtgcagtggggggactcgaccccctgacatggggctgcc tggagcaggccgcgtgacgtggggctgcctggccgcggctctcacatggtggttcctgctgcactgatggcccaggggtc tctggtatccagatggagctctcgcttcctcagcagctgtgactttcacccaggacccaggacgcagccctccgtgggca ctgccggcgccttgtctgcacactggaggtcctccattacagaggcccagcgcacatcgctggccccacaaacgttcagg ggtacagccatggcagctccttcctctgccgtgagaaaagtgcttggagtacggtttgccacacacgtgactggacagtg tccaattcaaatctttcagggcagagtccgagcagcgcttggtgacagcctgtcctctcctgctctccaaaggccctgct ccctgtcctctctcactttacagcttgtgtttcttctggattcagcttctcctaaacagacagtttaattatagttgcgg cctggccccatcctcacttcctctttttatttcactgctgctaaaattgtgtttttacctacaaaaaaaaaaaaaaaggc acgagcatggcccttgtgatccaggtggggaaactaaggcccagagaagtgaggaccccgcagactatcaatcccagtct cttcccctcactccctgtgaagctctccagcatcatcgaggtcccatcagcccttgccctgttggatgaataggcacctc tggaagagccaactgtgtgagatggtgcagcccagtggtggcccggcagcagatcaggacgtactgggcgaagagtctcc tctggggaagccagccatgctgcacctgccttcagaacagggcgctcctgagaccctccagcgctgcctggaggagaatc aagagctccgagatgccatccggcagagcaaccagattctgcgggagcgctgcgaggagcttctgcatttccaagccagc cagagggaggagaaggagttcctcatgtgcaagttccaggaggccaggaaactggtggagagactcggcctggagaagct cgatctgaagaggcagaaggagcaggctctgcgggaggtggagcacctgaagagatgccagcagcagatggctgaggaca aggcctctgtgaaagcccaggtgacgtccttgctcggggagctgcaggagagccagagtcgcttggaggctgccactaag gaatgccaggctctggagggtcgggcccgggcggccagcgagcaggcgcggcagctggagagtgagcgcgaggcgctgca gcagcagcacagcgtgcaggtggaccagctgcgcatgcagggccagagcgtggaggccgcgctccgcatggagcgccagg ccgcctcggaggagaagaggaagctggcccagttgcaggtggcctatcaccagctcttccaagaatacgacaaccacatc aagagcagcgtggtgggcagtgagcggaagcgaggaatgcagctggaagatctcaaacagcagctccagcaggccgagga ggccctggtggccaaacaggaggtgatcgataagctgaaggaggaggccgagcagcacaagattgtgatggagaccgttc cggtgctgaaggcccaggcggatatctacaaggcggacttccaggctgagaggcaggcccgggagaagctggccgagaag aaggagctcctgcaggagcagctggagcagctgcagagggagtacagcaaactgaaggccagctgtcaggagtcggccag gatcgaggacatgaggaagcggcatgtcgaggtctcccaggcccccttgccccccgcccctgcctacctctcctctcccc tggccctgcccagccagaggaggagcccccccgaggagccacctgacttctgctgtcccaagtgccagtatcaggcccct gatatggacaccctgcagatacatgtcatggagtgcattgagtagggccggccagtgcaaggccactgcctgcccgagga cgtgcccgggaccgtgcagtctgcgctttcctctcccgcctgcctagcccaggatgaagggctgggtggccacaactggg atgccacctggagccccacccaggagctggccgcggcaccttacgcttcagctgttgatccgctggtcccctcttttggg gtagatgcggccccgatcaggcctgactcgctgctctttttgttcccttctgtctgctcgaaccacttgcctcgggctaa tccctccctcttcctccacccggcactggggaagtcaagaatggggcctggggctctcagggagaactgcttcccctggc agagctgggtggcagctcttcctcccaccggacaccgacccgcccgccgctgtgccctgggagtgctgccctcttaccat gcacacgggtgctctccttttgggctgcatgctattccattttgcagccagaccgatgtgtatttaaccagtcactattg atggacatttgggttgtttcccatctttttgttaccataaataatggcatagtaaaaaaaaaaaaaaaaaa (SEQ ID NO: 12086) gaattcctctggtcctcatccaggtgcgcgggaagcaggtgcccaggagagaggggataatgaagattccatgctgatga tcccaaagattgaacctgcagaccaagcgcaaagtagaaactgaaagtacactgctggcggatcctacggaagttatgga aaaggcaaagcgcagagccacgccgtagtgtgtgccgccccccttgggatggatgaaactgcagtcgcggcgtgggtaag aggaaccagctgcagagatcaccctgcccaacacagactcggcaactccgcggaagaccagggtcctgggagtgactatg ggcggtgagagcttgctcctgctccagttgcggtcatcatgactacgcccgcctcccgcagaccatgttccatgtttctt ttaggtatatctttggacttcctcccctgatccttgttctgttgccagtagcatcatctgattgtgatattgaaggtaaa gatggcaaacaatatgagagtgttctaatggtcagcatcgatcaattattggacagcatgaaagaaattggtagcaattg cctgaataatgaatttaacttttttaaaagacatatctgtgatgctaataaggaaggtatgtttttattccgtgctgctc gcaagttgaggcaatttcttaaaatgaatagcactggtgattttgatctccacttattaaaagtttcagaaggcacaaca atactgttgaactgcactggccaggttaaaggaagaaaaccagctgccctgggtgaagcccaaccaacaaagagtttgga agaaaataaatctttaaaggaacagaaaaaactgaatgacttgtgtttcctaaagagactattacaagagataaaaactt gttggaataaaattttgatgggcactaaagaacactgaaaaatatggagtggcaatatagaaacacgaactttagctgca tcctccaagaatctatctgcttatgcagtttttcagagtggaatgcttcctagaagttactgaatgcaccatggtcaaaa cggattagggcatttgagaaatgcatattgtattactagaagatgaatacaaacaatggaaactgaatgctccagtcaac aaactatttcttatatatgtgaacatttatcaatcagtataattctgtactgatttttgtaagacaatccatgtaaggta tcagttgcaataatacttctcaaacctgtttaaatatttcaagacattaaatctatgaagtatataatggtttcaaagat tcaaaattgacattgctttactgtcaaaataattttatggctcactatgaatctattatactgtattaagagtgaaaatt gtcttcttctgtgctggagatgttttagagttaacaatgatatatggataatgccggtgagaataagagagtcataaacc ttaagtaagcaacagcataacaaggtccaagatacctaaaagagatttcaagagatttaattaa ca gaatgtgtaaca cagtgccttcaataaatggtatagcaaatgttttgacatgaaaaaaggacaatttcaaaaaaataaaat (SEQ ID NO:12087) gatcaaaatttttacctattatgcatttgatatataaataagtatataaatgcacacacagacacagcaatgatggtgaa cagtcttcatacaattatatggatgaatctcataaaatgctgagttaaagaaatcagaccaaagaacatatactgaaaga ttctctctatatacaaagttcaaaaataggtggaccaattcatggtggtgttagaaatcagaagagaggctacctttgtg gggaggggacagtttaatgcccagaagcggtaaataaggaatcctctggggagtggtaatgatctggatgctggctacag gatgtgttggttgtaaaaatgcatttttttatatctagctttttccatgtgtatattatacttcaaagaagttcagttaa taatttctcatgtcactgtagagtagctcagttagccccagcaagcctctggcttaatcttgttttaccttaagccatca gtcatttacaagtaggaaaattcacagggaaagttagagtataaaatccagaatgaaggtttactgggtaagagtctctc cattttccaaagcccgtttatttcttgattccagttcttaagaagtctcagcattgtgtctttttcatgtatcttacaag aagacagcatgtgcttctaacacctgatacattgtatctaccagcacttggtaaacagaaaagaaccacatttttcttgt aggagaaatttggtgcctatttcctaccaggcaccaataagtgggaccaataggtgggattaaagatacagtagaaagta tttaaaacttgccagggggcaatagtctgaaaataagtaaattggtgctatagaatggaagttacaggcttctttctttt ttcccacaagatctgctccttgagcccctagagacttttctgtctgttactgtttcttcattcctcatctgcagagccag ccctgagaagtgcagaccaaagccagggaaggctctgcaaagatgtacaaatggaagtcaccttaataacctctgactgc tgcgcataatacatttcactcaaaagaggggttaaacaatggaacagaatacagaggccagaaataatgctgaacactga caaccatctgatctttgacaaaatccacaaaaacaagcaatggagaaaggactccctattccataatggtgctgggataa ctgtctagctatatacagaagattgaacctgggccccttccttacatcatatacaaaaaataactcaagatggagtaaag acttaaatctaaaaccaaacactataaaaaccctggaagatagcctgggaaataccattctggacataggacctggcaaa gacttcatgacaagacaccaaaagcaatagcaacaaaaaccaaattgactaatgaaactaatgaaactctttagttgtac aacagatagtttatctgtacaacaaaataaactatcaacagagtaaacaacctacagaatggaaaaattttttgcaaact atgcatctgacaaaggtctaatatccagaatctataaggaatttaaacaaatttacaagcaaaaaaatgacctcattaaa aagtgggcaaaggacatgaacagatgcttttcaaaataagacattcacacatccaacaaccatatgaaaagatgtttaac atcactaatcattagaggaatacaaatcaaaagcataataagataccatctaataccagtaggaatgactactattaaaa agtcagacaataacagatgctggtgaaggttgtggagaaaagggaatgtttatgcactgctagtgggaatgtaaactagt tcagccattgtggaagagagtgtggtgattcctcaaagaatgtaaaaccgaactgcctttcaatccagcaatcccattat tggatatacaccaaaaggaatagaaattgttttaccgtaaaggcgcatgcatgcatatgttcattacagcactatttacg atagcaaagacatggaatcgtctaaatgcccatcagtggtagactagctaaaaaaaaaaaaatgtggtacatatacatca cagaatagtatgcagccataaaaatgaacaagatcatcatgtcctttgcagcaacatggatgtagttggaggccattatc ctaagcaaattaatgcaggaacagaaagccaaataccacatgttctcatttataagtgacagctaaatattgagtacaca tggacacaaagaagggaacaatagacatgggacctacttgagaatagagggtgggaggagggtgaggatcaaaaagtacc cataggacactgtgcttattacctgggtgatgaaataatttgcacaccaaacccctgtgacacacaatttacctatatag aaaacctgtgcatgtacccctgaacctaaaagttaatggtgggggggtggggttaagctactttgtggtataaatctgag cattcatattaaaataaaatatttacctcattagagtaattaacatttattaagcaaagagccaagtaccttacacacat gatgtttaatctcacaatgatctttaatctcataacaaccgtccattgtatgtacatatgtggaaattgagccttggaga gattaaatgcatggggcatgccatttgactagaaactggaagcatcaggatttaaactcagttctgaatggttttgtagg ctttgttttttccacattatagcatggcctgccatgaagaacaggtcctttctggtgtttgtcttgtttggtttaagtga agcaaatatttatttaaatattcaagatatgctgttaaatttttactcaaaaatttgagtacagtatggatcttctgaag ccaaataactcttattcaatgcttagttgagaaattttatggagtagttctcaatttttatgtagttccactgcaaaggt aagtcttatggaaagattcactgtaattttttttcctcatttggacatcagctttttcttttcctcagacccgctgaaag ataatttttaaaataaaaaccttgtttttatatcaagtggggacattttttccaaatgaaaaccgtgtattcattttata tgataaaatcaatgttattatttttaaaattttgatttaaaaatcattaaaaataaattttcagatattacctgaaattc taccatccagagataatagtgcttaaagatttgatatatagacacacacacatatatacatatatatcatcctaaacttc tttgtataaatgtatataaagtttttaataaaaactaggagattaatgccctttgaatgaaaataaatacaatgtgtatg ctttaacatcttgcctttactttataacatttatcacagcagtcatgagataatgatttacatggtcattgttagtaagc taatagctaagtgcatgaactctggagctagcctccctggattttaatcccagatctgtcactgaccagctgagcaatac taggtaaattgctcttgttccttagtttcttcatctgtaaaatagagataaaaataatatccacctcataggattggtgt gagcattaaatgagcatacgtatgtaggccacttaacaacaatgccttcacatactgaacacaaatatacgagctgttgt cttattgggctcatgtttttcctaccactaagccgcatgcatgcaaggaccatgttggttttgttccacattgcatcccc aacctggtatacagtgtgcattcaatagttgttgactattattactagtggcatttaacaaatatctgttaaatgagtga agaaatacccatttactgcaagtgtgtctaatattgatggcataatgggggaaactcaaactctggagtcaaacaggttt taaaaccttattccctcatcctcagttattgacgttttttttttggcaggtgtgtgtgtgggacaacttattgaactttt ctgaatttccagcttcgcatatataaaatagagatagtgattcattcttgcaatgtatggatttgagacaattgtgtaag tttatcaataaatagtagctatttttgtataagtattacatataatatccaggccactgctttgcataacccaaaagggg caccattcatgcagaatacaacataaatggtgtccctggagcagtgcagtataggaaccctgaggggacctacagtatac tttatagttcatagattacaaattatccctttatcagagtctctcaaggttggatgtatttgaggtccataagagcaatt taggattaacagtagctgcagaaaccatctgcagtgatattctcattttaaatccgcgggaaagaagacagctataaact tgggacctgggtttaagcattttaaatgccaagttcaccattttctaaaacacaacaaatacccagtgagagagggagaa gggaagtaaatgcctctgaataagcaagttaatgtcagtagttgtactgtatgcatattgatgaacaatagaggaaccaa tgtccaatcagatgagcaggatatttggcaataacaagttgcctttgaggaaaaatgattttcttggcaagttctttatc agcattacaaagctaaaagctacgcttatcatcacttatactagcataccctgttgtgcaaatgctgtctgtgtttgcat ctgctattgttgatgcctggtgcatgaatcaggactccagcccacaagttttcccagaactttcttatggccatcatctt taagtgtctggtgaacagtcatagtttggtacacaaaagggtcaacctgggggatggctagggtttgactcagtcgttac atttcaatagagcaggaaggggaaatggtggcctgtaacctcagggaattttgccagttggtccaccccactctctctct cctgctctgaggaagtggcacagcctagaacagcaccacaggtgagagaaatgcaaaccctaaccagagaagcagactct ttgccagtagtaatagttcaggaccaccaccagcttttattaaaatttttaataacactcaagtattggcagaaagaaat aatcttgggttaactataactagaatattgactcttcctctgtggaagaatcagccaatcacatttgtttacatcagttc ccctgaagaagaaaaatacactgatgttgcagcaagacaaatttaagctagatgtaaataacttcctttagcctgtaatg ctaggctaattacatattggaactattttttcagggaagaattgtgtagggtttcagggaagaattctgaagaaaatata gagctgaaatgatcttgcagctcactgaaactgcagggtttagatccacactgatactcgttctattatcactgtaatga aggctgatggaataagtaaaaatgttttgtattagtatgtttttacacttatttgcaaggcataaataggttaggttttg atcttaatttaattctaacatgtattgtgcacaagctgtgagcagttttcaggagttaggtatctggccatgactgattt ttcaggagttaatcatctggtagaagggtcatacacaataggaagatgtgtgtgacaggttgtgatcattactataatca cacagagagctgtagaattttaggctggcagggtggctcacgcctgtaatcccagcactttgggaggccaaggcaggcgg atcaagaggtcaggagatggagaccatcctggctaacacggtgaaaccccgtctgtactaaaaatacaaaaaaaaaaaaa agccaggcgtggtggtgggcgcctgtagtcccagctacttgggaggctgaggcaggagaatggcgtgaacccgggaggtg gagcttgcagtgagccgagatcgcatcactgcaatccaacctgggcgacagagggagactcagtctcaaaaaaaaaaaaa aaaaaaagtcatgttagatccagaggggtagcaactggggctgggctgtcagtcaactcagtcaactcagtcaactctgc tcccccacaggagatgccagtgatgcattttcatggccaacattgtcagtcagcatcattgaattactcctgattataga gacacagctgcaaacgattccccattaaatatgatgtttcttgcaatgtttggaaggtactcctttttagtaagggaaat cccctcttctggcttgctgaaagttttttctttccattttaaaaatcgtgaattcctttttgcaatattgaggtggttat atggtttctcttctctaatctgttaatatggtgatttaatggttagaaattttctaatgtaaattccactcatattgcag aaataaacctaaactgagcatgaggctatattttttatttgcttctatatttggttgctatacagtattatgtttaagat ttgttcacatatatttgtgaatgggattggactatttttccttcttgccgatttttatctggtttttaaattaaggatat tttagacttatgaaatatttggcaaacaatccttggcaagtaattttttggggaatttgttttggctattttgagtatta cccaatatattttaattaagttattcttaatgttttcttaattaaaaaaattacctactctagagatattctttatgtac tccagattttgtctatttataccacttttcttttttcctcgatgagtgtcatagatgttcatctatttttttatcttctt tgatcttctcttattccttgtttctattaacttctgaagtttattattttcttttttccacttccttatggtttattctt tcaatttttctctaacttcttaagttgggtgtttaatttttagcttgctttgcttttttaggataagcattaaaactaca aattttccttgttattcttttgctgcaccccaaattgttgatatttctattgtctaatttctattcaattagaatacttt aaagtttctttttggtttttaaaaactaactttttaaattgacaaataaaaattgtgtatatttattgtgcacagcatat ggctttgaaatatatgtacattgtggaatggctaaatttagcttattaatgtatgcattatctcacatacttatcatttt ttgtggtgagagctatgtgacttttgaacttatgagttatttaaatatttttaaattattaagcatattgggattttaag taatttacctttttattattaacttataacaagtagaacagttaacctgtatgattctacatcattgaaatttattgaca tttgcttcatagtctattatatggtctacttttgttcatgttacatctgtagtagaattggctaatagttgagtaaagta cacatatgtctatgaaatcaagtgtaatccagagaaaaagagaaatttactgaatatattgttctaggtgctattatatg ttgtcatgtttaatcctcaccacaattgtatgaggcagccataattaattccactttacacatgaggagcctgagggtta aaaaaaaagctagctctactatttgtaaagaatgaagcaaagatacaaatgaaggcccacatatcctataactagatatt taagcattttaattcaagctttaaaactgctaaataaaatgtgctccaatttctatattgacagacataccttcctaatg agctggggttcgaatttagaaatctttgatgcttcagagtccacactgaaatgtggaggcacatagtgagttggtcccca gccttcagtccacccaccttctctttactaaatcacctttcacatacatgtatgaacaccccagcctccaagtccaaacc ctaaacaaaatgggacacccttgtgcatacacagagacacagcccatcctcaggaaaacctggaaaagtccatacaagtt ctggaagcaagcttgggacggtttcagtagtgtggtctataagggaggcctcagaagacaggttttcttaattctgtgaa cttctcccacagtagaaagggtgctggaggagggtcagagtgaggacttctaaagcatgggtcctgagtaggggccactc ttgcccaagtctaagaagggtactagaatagcacactactactagatactagaacccagatacaagcacaggtcttctga aattaataataataataactattaccattattataccagtagctgtcatttatttagtgcttattatttgccagtcactg ttctaaattctttacatgtattatacaactgccatataactgccatatgagggatgtaccctcattgtcaccattttacc gatgagaaaactggcataaaacgtttaagtaacttgtccaagttacagagcttagtgaagccacaatgttgctcaatttg ctctcaaacttcaaagggatgggaaggacacctaagtcatagagtctttaagaatcagagctagaaggaatcttagatgt tatctagtcagcctcctcccattacagtccaagagaagatggccctgagttacttgtagctatttttgcatgtgaattgc aagtgaatatacattctactgaagataaaagatatttaaagatatcgctggatataggaacagtggttttaaatctctag gctttaacttttctcagaacaagaaatcctttttggttttaatctatatgcacatctgtatttttctcaattatcgggta gtaaaatataacttttcttctgtaatattttttaactttaatgagtgttcctcataatagaaaagtttggaaaccattgc tatgggtatatactttctaaagggatagtaatttctctagaatattcatttaatgctccagaagtaattagcacaattgt gcaagtctgtgcatcatcaactatacattctgcctgtttactccaaatccacatgaaactgattatacagtcaaaggcga gcccagtggagaggcatttttggagacttcctggtacattgagacagggtcggccagtctgcgttagggtcttggtcaaa actgcatttctgaaactaaactcagattgctttcttttaaggggtcagaactgattcaaatctacatttttaaaagcctt agatgtggggcttttcctattcccagtctccgctattggtctttgtgaatccacaggcaatttggccacatccttgactc tctcttatattaagaattaaacagctaagttcatgcagaggaaatataacaaaggagggactttcctacaagatctttga aaaatggaacatttgcataagtcatatttagccagaactgttgttttatattttcctttctgaatactttgttacacctc ctcccagccaaccccccccctccctgaccccaactagtcagagaccaaagccttcacaatggtttacacttgaaccttcc tggccccaccctcatcatcacgcctgaataattacattcactgactggtctcccctgcttccgtttatctccactcctaa accctctgacaccttaatcttcccagaataccattgtgatcctgttccactcttgctcaagttttcccagaaactagagt acaaactttataagctttagagttgaaagccactctatctctttttcatccccaggtctctgccaaggcagtataacctg tccaacatctctaacttcaatacctttgtcttagatactagactctcctcctggtttctaattaaacctgatctaggatc taattttgcctctgaattctgttgccctttgccaagtgatctcttcctcctctgagccgcagcatctctgagcttgcaca cttagcatagccatagcacacacagccttagcttgcagttcagggtgtttaccttccctccccttccagatgctggatcc ccagggataggaactctgcccttatgtgtccatagcccctggtagtatgtcttgcagtcgtacattttcagcaaatgttt aattggttaattgaagacaactgtcccatgccttaagcctctctttttgctaaacatgcctgtgtcctttgtcattgaac aactattttgatctattttcttcctgacataggggtcagttccgaggatgctgaaatcaagagacatagcttattctctc aaaattgctttcaagagtgattttgttgtgaattgagaactggctgcctacttttggactacccacttcagcaagagtgt ttgaaaccaaatctattctaagtaattttttattcccttttctctatggcattagacacacagctcttttaaactacctt tcgttatctattaaacagacattcagtaactctatagacactgtctagctatatgaacttagacaaactaatatctctga gcttcagtttcttaaaatttaaaatgaggacaataccatctatggccggggattaaatgctatgaggaatgtaaaccaga tgtcaggtaccatctctctaaaatccagataaaatgaattaaaaatactggccgcaaaccctctctaagagttctcaaaa ttctcagagagcttaattttcatgctcaccatagcaccgattttcttctaaatattttgtttctaccaaaatattttgtc ccaattttgccttttatggctatttcttcatatccactttcccaaactaaagaagcagccccttcaccttaaactcctcc ttcaaagcaacctaaatacaggtctgggtttgtattcctagtgggatgttacagaggttagtgtgatgcagaggaggagt catgctgtttaaatccatactagtccccagaggccaggctgcttctgccacccctacccctcccgccacagagctcttca gcttctcacatttctagttcttctctctctactttcattaccttctctctttttttttttcttctcatgtgctcacggga gcagagaaaattaactcctctaagttttcttaacacagagtgccttaattacatattactattgtttgagttcctgccaa cactacgtctgtagggtcacacctgctatattagaggcttatcaaaaaaagatagctttctcctaaaaagggatttggat gcctactaagataactggatgccaagataagtttaacctaacaaactttattattattattattattattattagagata ggtacttattctgtcacccagactgcagtgcagggatgcaataatagctcactgcagcctcaaagtcctgagttcatgca atccttctgcttcagctccctgagtagctaggactacaggcatatgctactctgcccagctacttttaaaaaaataatta gggatggggtcttgttgtattgcccaggctcgtctcaaacttctggtttcaagcaatcctcctgccttttacctccctaa ttgttggagttacaggcatgagccacagcactcaaccaagatttaaaaacttttaaaagaaatcacattacttactgtta tcatcattatggttactaccagtgttaaaacaattggtattgaaaacaccactaccagatcaagcttcaaaccaagatgt caagtaaatattattgtcagacctctgagcccaagcctgcaggtatacacccagatggcctgaagcaagtgaagaatcac aaaagaactgaaaatggccggttcctgccttaactgatgacattccaccattgtgatttgttcctgccccaccttgactg agggattaaccttgtgaaattccttcccctggctcagaagctccccgactgagtaccttgtgacccccacccctgcccac aagtgaaaaaccccctttgactgtaattttccactacccacccaaatcctataaaacagcctcacccctatctcccttcg ctgactctcttttcagactcaacctgcctgcacctaggtgattcaaaagctttattgctcacacaaagcctgtttggtgg tctcttcacacagaccatgtgacatttggtgccgtaactcagatcggggaacctcccttgggagatcagtcccctgtcat cctgctctttgctccatgagaaagatccacctatgacctctggtcctcagaccaaccagcccaaggaacatctcaccaat tttaaattgggtaagtggcctctttttactctcttctccagcctctctcactatccctcaacatctttctcctttcaatc ttggcaccacgcttcaatctctcccttcccttaatttcagttcctttctttttctggtagagacagaggaaacgtgttct atctgtgaacccaaaactccagcactggtcatggacttggaaagacagtcttcccttgatgtttaatcactgcagggatg cctgcctgattattcacccacatttcagagctgtctgatcactgcagggacgcctgcctggatccttcaccttagtggca agtaccactttgcctgggtggcaagcaccacctctcctggggggcaagcaccacctctcctggggggcaagtacccccca accccttctctccatgtctccaccctctcttctctgggcttgcctccttcactatgggccaccttccaccctccattcct cccttttctcccttagcctgtgttctcaagaacttaaaacctcttcaactcacgtctgacctaaaacctaaatgccttac tttcttctgcaataccgcttgaccccaatacaaactcaacaatggttccaaatagcctgaaaacggcactttcaatttct ccatcccacaagatctaaataattcttgtcgtaaaatggacaaatggtctgaggtgcctgacatctgggcattcttttac acgtcggtccctccctagtctctgttcccaatgcaactcatcccaaatcctccttctttccctcctgcctgtcccctcag tcccaaccccaagtgtcgctgagtctttccaatcttccttttctactgacccatctgacctctcccctcttccccagact gctcctcctcaggtcgctccccgccaggctgaatcaggctccaattcttcctcagcgtccgctcctccaccctataatcc ttctatcacctcccctcctcacacctggtccagcttacagtttcattctgtgactagccctcccccacctgcccaacaat ttcctcttaaagaggtggctggagctaaaggcatagtcaaggttaatgctcctttttctttatccaacctctcccatctc agttagtatttaggctttttttcatcaaatatgaatacctagcccactccatggctcatttggcagcaactcctagacat tttacagccttggacccagaggggccagaaggtcatcttattctcaatatgcattttattacccaatccactcccaacat tagaaaaagctccaaaagttagactccggccctcaaaccccacaacaggacttaattaaccttgccttcaaagcgtacaa taatagagtagaggcagccaagtagcaacatatttctgagttgcaattccttgcctccactgtgagagaaaccccagcca catctccagtacacaagaacttcaaaatgcctaagccacagtggtcaagcattcctacaggacctcctccatcaggatct tgcttcaagtgccagaaatctggccactgggccaaggaatgccctcagcctgggattcctcctaagccatgttccatctg tgtgggaccccactggaaatcggactgtccaacttgcccagcacccactcccagagcccctggaactctggcccaaggct ctctgactgactccttcccagatcttcttggcttagtggctgaagactgatgctgcctgatcgcctcagaagcctcctgg accatcacagatgcttttggtaactcttacagtggagggtaagtccgtccccttcttaatcaatgcagaggctacccact ccacattaccttctcttcaaggtcctgtttcccttgtcttcataaatgttgtgggtattgatggccaggcttctaaaccc cttaaaactccccaactctggtgccgatttaaacaacattcttttatacacttctttttagttatccccacctgcccagt tcccttattaggctgagacattttaaccaaattatttgcttccctgactattcctggactacagccacatctcattgctg cccttcttcccaacccaaaagtggcaactcctttgccacttcctctcatatccccctaccttaacccacaggtatgggac acctctactccctccctggcaacaaatcacaccctcattactatcccattaaaacctaatcacccttacctgggtcaacg ccagtatcccatcccacaacaggctttaaagggattaaagcctgttatcacttgcctgttacaacatgtccttttaaagc ctgtaaactctccttacaattcccccattttacctgtccaaaaactggacatgccttacaggttagttcaggatctgtgc cttatcaaccaaattgtcttgcctatccacgccatggtgccaaacccatatactctcctatcctcaatacctccctccaa aacccctccataacccttattctgttctggatctcaaaacatgctttctttactattcatttgcacccttcatcccagcc tctcttcactttcacttggactgaccctgacacccatcagcctcagcaacttacctgggctgtactgccgcaaggcttca tggacagcccccattacctcagtcaacccaaatttcttcttcatccattacctatccaggcatagttcttcatgaaaaca cacgtgctctccctgctgatcatgtccagctaatctccccaaccccaggactggcaaattgactttactcacatgcccca aatcaggacactaaagtacctcttggtctgggtagacactttcactggataggtagatgcctttcccacagggcctaaga aggccaccgtggtcatttcttcccttctgtcagacataattccttggtttggccttcccacctctatacagtctgataat ggacaagcctttactagtcaaagcacgcaagcagtttctcaggctcttggtattcagtgaaaccttcataccccttaccg tcctcaatccttaggaaaggtagaactgattaatggtcttttaaaaacacacctcaccaagctcagcctccaacttaaaa aggactggacagtacttttaccacttgccattctcagaattcgggcctgtcctcgaaatgctacaaggtacagcccattt aagattctgtatggacgctcctttttattaggccccagtctcattccagacaccagcccaacttgaactgtgccccaaaa acttgtcatccctacaatcttctgtctagtcatactcctattcaccattctcaactacttgtaaatgccctgcccttttt tacagtgctgatttatacttttcctccaaaccatcataactgatatctcctggttttacctcaaaccgccacccttaagt ctctcttaaagtggatagaagatcttcagtgacaaggtacactccaatactttcaccctaataaagccctattctttact tttatattcactcttattcttgttcccattcttatgccactctctacctctccccagctatctccaccacactatcaatc tcactcactctctcctagccatttctaatccttctttaacaaacaattgctggctttacaatttctctttcctccaaaat caccgagtcctcaatttactcactgctaaaaaaggggactctgcatatttttaaatgaagagtgttgtttttacctaaat caatctggcctggtatatgacaacataaaaaaaactcaaggatagagccaaaaaccttgccaaccaagcaagtaattatg ctgaacccccttgggcactctaattagatgtcctgggttctcccgattcttaatcctttaatacctgtttttctccttct cttatgcagaccttgtgtcttccatttagtttctcaattcatacaaaaccgtatccaggccatcaccaatcattctatac gacaaatgttttaagggaggagaccacccctcatattgtcttatgcccaatttctgcctccaaagaaagaagtaaaaatg aaaaggcagaaatgaaatccacaggcagacagcctgatgccacaccctgggcctggtggttaagatcaacccctgaccta a cagttatgttatctatagattacagacattgtatggaaaagcactgtgaaaatccctgtcttgttctgttcctctaat taccagtacacgcagcccctagtcatgtaccccctgcttgctccccctgcttgctcaatcagtcatgaccctctcacgca gacccccttagagttgtaagcccttaagaggaaaaggaattgttcactcggagagctcggtttttgagacatgagtcttg ccaatgctcccagctgaataaagcccttccttctttaactcagtgtctgaggggttttgtctgtgtcttgtcctgctaca gtttcatctaacaaccccataatatcaccccttaccacaaaatcttccttcagcttaatctctcccactctaggttctca cgccacccctaatcctgctcgaagcagccctgagaaacatcgcccgttatctctccacaccacccccaaaaattttcact gccccaacactttaccactatttcgttttatttttcttattaatataagaagatagaaatgtcaggcctctgagcccaag cctgcacgtatacatccacatggcctgaagcaagtgaagaatcacaaaagaagtgaaaatggctggttcctgccttaact gatgatattccaccattgtgatttgttcctgcgccaccttgactgagggattaaccttgtgaaattccttcccctggctc agaagctcccccactgagcaccttgtgacccccacccctacccacaagtgaaaaaccccctttgactgtaattttccact acccacccaaatcctataaaacagccccaccccatctccctttgctgactctatttttggactcagcccacctgcaccca ggtgattcaaaagcttcattgctcacacaaagcctgtttggtggtctcttcacaccgacacgcgtgataattattatatt acttttaactaaaaccctttcagagtctcgcagggaaggctgtatatatctcataaaatgttggggcccactggatcaga caaggccacaaaggccaaagggaagtaaagatctcattatttctcctaataatttccctgtcctttgtcataaatggtgg gtaggctgttatggtgatggcagattttctttccataaaatgtccataataggacatttgaacagaagggaaaaatcaaa ttgctgaagttgaaagagggcaatgcaaagaactttggagaaagaactgtacagagaagtcaactggcagatgggaggaa gtttaaggggaaaaatatagatgtctaaagaatacatttattcattttccacagtgcaatttggacaagaagcctctttc ttgcttctttctattctcattaaatcattagagctcaagcaatccttctgcctcagcttcccgactagctaggactacag gtatgtgctactatgcccagctaattttttaaaaattagattttaatttggtgaactatttctgtaggaaactacaataa tacagcccaggcacattgatcttgggtgaacaaatcagaaggaatgaataattctgtgttcctgggactctgacaatttc atgaacttggtactctgagtaaagcataggaggagttatttcataaaatgtggagcacaatcatgtgacaaagataatgg gatccccatttcataaataaatctgaagttcagagagagtaacaactggccagggtcacatcacggagacagaggcaggg ttcccactgatgcctctgactccctgtcccaggcccttcctcctcccgcaagcagaagtgcagggggcagagctgaccct gtgcagtgaaaatctgagggctgagttcctattggaacacaagtgaaagacttcctggcttctaatctcaggataaggac tcagagctccatctgttccagccttaggataagaaccagaatcttacaccatgaaagcatgaaaggtaagatttgagtga ggaaaaaaaaaaaaaaagtctgtgtttcagattcagttcacaaagcagtttcatacttaaggtaccatcacaataaccct gtggggtaagcaaggcaaatttcattcttgttttatgggcataggaagtaagtctcagggaggttaagaccaaggtttct ggagaattttatattatgaatcttgatttatgggattactattatgtaattcctaagatcatataggaatcctagagctt gaatatagaactttatttttaaatctatatacatcataattacaaggagtagtgtccatttgggttccttggccctgatg tgttagtggaataaacatttttgtcagggttgccatgtgtgtctgtgcacgtgtgcactgtacacctccaggggatgtac cctaaaccacatgaatgtgatttgcacatccaagatttacagtgtactatagggagaatcttttgcaacagcttttgcta taatacagaatctgagatgtctttgagaaagaaaagtgtaatcattaccaaaaaattattctcataatgtgtgcaaattt gtatgaaatctatattggccatgggacaaggaggtatttccagctagcttctgaaagggctcta ctctcataagaatt cagctgttgacattaggtgatatctgcccaggtcatcagatgccatagagaaagagggtttgctgaaacttatatcagca gtgcactgtatgctctttctgatttatttgaacattcatttattgagtgtcaagtaatgcactagatactccagggatct gacacaaactctgccctgaaggagcatgtaatctcactggggagaaaacaaaacatatgataatttcaaaataacaaact aggcaaactagttaacacttaaaaagcaggctttattcaaatgcaaaattgcatgttacagggtaacctttcagtaagaa gccaggaagaggagctcatcatgggttggattagtaaaggactagttataaaagaagtggtggggttgagggaggcctga gatgaaatttaaagaatatgtagaatctaggtaagtggataaaaggtctgggggcaggggaaaggagagcatttcattgt gaatcaaggaatttctccacctgttttaactcttccatatgacatcaaagagatgtcacttgcagctagcatttcagtga tgttttcttactaataatatcgtgataaaagaaacattgactataagaaataggaatgggtctcataaaaggaaacagca aaacccccaaactaaaaaacagcgcaggctatttctctcttctctccttttgcttggcactcatgagatgctaggtgtgg aagtcagccaactgaaaaagagaggtggctgaagaaggtggggaggctgaagccagttaaataggatggtccaattcaca gacggcgaggctacagtgcaaataggactctttcaacttgagcaggaccccattacttcactggagttagaaagaaagga gagcgtagactttttgaactttctataagagtgtacctccacagtatacagaagacgacgtgaaatttgatctgcaagaa aactgagtccatattcacatatgtatcaaatttgcacttcatttagaagtgtctgtcatcaagtacagcactgaattgaa actgaaaacaagagtcaagaaagagcaaagtcagccatctttatattccacatgaatcctttccctttatggtcttattt gtttctcctcagaaaagacaaaaagctgagctgtataaacacctgtgggctgggggttgagggataaatgaggggcgaaa tggaagctgaaggaactgttggtcaggtagaaatcttcccagatgcactgaaggaaacacacttcatgtttgacgtagga ggtgccaccacacaaaacgtttcatggaaggatttaaaggatctcatgatttttagtattccaagaattttctttcaeca agggcgatttaatatgggtcattcatactgaaagaaaaacaaaagataataagagtttaaaaattgcaaaacttggagtg ttagtagtaaaggtaaatattcattagagatgagaagaggagcaaggaaatgctttcagctggaaatctcagacaagagg ccaggctttaggaacctctgaagatgaacaaatgtaagcaaaccctagtagcagcacttctcagattttcatgtgcttac cactcagagatggtgttaaaatgcagactctgattcagtaggtctgagtggagcctgagattctgcacccctaacaagct ctttagtgatgcttatgccactggcgcacagaccccacttggagaaatttttgtggtgcatacggtctttgtctccagat ctaatgagtctgaaggacagtgtagattgattttttaaatttatgtttattttaatttaatttaatttaatttatttatt tatttatttttgagatggagtctcactctgttgcccagtccggagtgcagtggcacggaggcagctcatgcaaccacggc ctcctgggttcaagcgattcttccgcctcaacttcctgagtagctgggaatacaggcacgtgccagcacacccagctaat ttttgtatttttagtagagatggggtttcaccacattggccaagctaatctcaaactcctgacctcatgatccacctgcc acggcctccgaaagtgctgggattacaggcgtgagccaccgagcccagctgtagattgattttgagcagtggaaagtcaa ggaattagaaggcatgcttaaatggaaagtgaaattggagaaaatttaaactcatgaaatagtggtggttataaactcgt gataaattatatcctgggatataatttaatgagatggtaacacatttagtttaaagaaataagtgacactttttttgtgt gacacaactgtcttattcttggaaaggacaaggagagaatgaaatatggtatgtcttcacagcacctttcaaagggagaa ccagattctgaggagctggtctcatgatgaactgtcagggtaaaccacagttcagcagctgcaaatgtgcttgccaaaat agagacaaaaaaatgtttctgaaaacaaaatttcacatatgccctcctctgaggttggcatcatatcttcctgtgtatct tgggtgtagcttctatcctgccagaatttagacagtagaaaccaaatgaggtgataaacagagtcattttgcagaagagt caaaataacccagcaagaaatgaaaccacaaatgcccaaggagtcattcattcaccattcaaaagctaatagaaatgaac acaaactactatgaaaattcacccaagaacttaaaaaaaaaaaaaaaggctcatggtgtttagtgtgatagtattcattt tacctttgacttgttctaaaaacacaccatacttctaccccacccttcctcagtgccgtcacacaatggtttcagtgtga aaaaaaaaaccacgttactggaaaaggagggtgcctgggacttgccactctaagctggtagtcaagggtcttgagttcta aaagcataqgcgttaagagcatgattcctggatccaaatgagtatggatctcagcattgccatttattgtgacctcaggc tattttatttctctgtgcctgtttctttatcagtaatgaagatgttcatagacccttctcccacagacttaaaggcatat ttcatgatttaagacatgtaaaccattcataacagtatacaacatggaattaatatttgataaaggtttatgattattgt aactaactctgtcacttgctcaaggcctatagaaaacttacttaattagttcaactacaaaaagagtttgaatgtgatat ccaccaagatcatattcagacctagaattctgtgattcttatgaattaatacagccttggtcaataaatgagagctgggc aaataattcttctttgctaggcctttctagaccatctggtgaagcattcaagacttatgttattggggccagccttcctt tccaacttcaactccacaactcctcaataagccatgggctcaagaaagttctgctcagtggcccctgaaaaatgctttca tagtctcactaccataccactgcttacacaatttccttcctacagactgccttcctttcctgcttttctccatataccta aatcctatctattcttcataagcaaccttctttataacattttctataaccaccaagccaaatgaccttttccttcttaa atatagcacccattggccattaccatgctctgccttgtatttttctgatttttttctttctatattcctgtcttaactcc ccagctaggtaataattttcctgaaatcagggaccaggctgactcctcttgctgtctcaagaaagcttagcagtttccaa cacaaaaatgttcaataaacaactattaattgactgattataaaaaatcagtgaaccattaaacttaatatagcaatttg cttagcatggtaattagctttttgctaatattcttccagccagtctctcctcctgtgcctcaaggacatcttaaaaaaaa aaaatctagttgatctgcttccatctagtggcaattaaaacaggtggttccggtagccagaaaacagctctgggtagatt gtgccagaaaatactttcactcagtaggtgcgagtttgaaagaaatcttcacatctgtgggtttcctgccacagacatag ggagaccagcccagagaaagaagcctttcctcactagactccatttgcactagtaaagagaagacagagtaattaaaaag aataaaaagaacctccactgatcgtacatcctcatccagttacccctgccccacttctccttcacagccaaacattttaa aagagatgactgcttgttctgtctctactttctcatcctcagtaatgctcaatgcttggccgtctgacctctgtcttgat gtctgcactgcaaatagtctccccactgacacccttgttgcatccaggggatacttactggttctcttggcaatgtttga aaccgttcccctttctttgtttccttggcattcattaccccacactctttctcctcttccttctccctgcctggcaacat 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cctgtgtaacagagggctgcctttagtttgtggcaggcgtcatcgttccatttgcctgcatctttgtttctcttgatata gatctccacgcagtcctccttgttcttcttgttgttgggctcaccatctccccagttctctgcttcttcagtaagagatt tgttggttcccacccacgtccatattcctcctatcttccggattcctatccagtagtaagaacgactgaaaggcagagtc ttctccagatactcaatttccgccttgttttgtatggcaactaaatctgtgtaattgtctcggcagaatcttctagccct ttgccagttcatgggtttttcagaataatggtaagtccagcagtcggttccatgatgtgccaggaaatctgcaagacatc agtgtgacctatgcagacttacataatgttacagctaaaaagaacctagcactactccaggctgagctagacacttagag atgaggaaacagagcctaagagtgtatgtgaccatctcaggatcacagaatagttgtttgcagatttgaagtagaaccta gaccttctggcttgaatataagatgcttttatctaaggttctatttgaaacaaatttagtggttttctaggtttattttc ttattaatttttttctcaaaattatttcaggtgaaatttaaccaacatattttagacattcatatttctttttctttgta gctgttaatgatttacaactaattaccgtgtaatatcatataactatacaatttacgtatactttttaatcctggaatca tttcttgaaggccaacacatatgtacctatgggagaagcataataaggacaggaagaacagtgacatacttttaagtaac ctcttttacataaaaaacattttattttaccataggaagaactgcttctggaaaagcccaatataccactcaactcttat 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aaagtcaagaagaggaaatcagcatatctgagaagaaagatttcaggatcactttttttgagggtctgagaaaatgttta gtttctatattatttaaaaccagaattgaaatggggtgattcctatccttgccacctgcctctacaaccccaagagtttc tatctgagcatctaaacgtcttttaggctgaaaggctcaccatggctttgcttggtccttctctagttcttctgcagccc attgagcctcttgacttagcacaagggtctcaggtccttgcccaaagggagtgtgctgtgctgcaggtagactgcactga atgtcaacagaaagccttgctttctttcatttctctaacccagtctcacatcctcctcctcctccccttttccctcccct tcctcctgcacttctctttcctctttccccacccctttcctagactggcctctattgcctcccactgagacaaaaatgaa ctgctgatcagaaagtaatgtgactagattctctcttccttccctcctttctatccttccttccattctcctatgcatct ttccttaccctcctcctccttcactcattgttgttgctgttcttcttcctcttctttttcctcctgctcctcttcttcta cttgttcttgttcttgtttttgtttggttcttgttctcctcttcctccttctctctctcctcctcctccttcttttccac caccctcccctatctttttcataaatgctaaactaactcttggctacctgtggtaaatggcccttggaaattgcaaatac tacaaatcaaaactgcatttcagacatatttatgatgtttgcaaaacttcagtagagctaagcagtggacttgactcgtt tcggttccttcacctccgtctttccttgctcaccacctagtggacgtccttgttagtggcacttcctgaagttaacccct 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tccactctgtatcaggaatgtgctaggttctgggaatacagcaatgaacaaggtaatttttccctacccctaaggaactt agagtttagtggggaagacagacattaaacaaacaattgtgcaagtaataatctataattatttattacaattaaaggaa ggaagagacatatggattatgagggcattaaagaggagacctagtgtaagtagccagttctcgtgaagggacatgtatta gttggagttctccagagaaacagaaccaatggtgtgtgtgtgtgtgtgtgcgtgtgtgcgtgtgtgtgttggggtgtggg ggtgtggtattttttatagaaattgtctcacacaattatggaagctgagaagtcccatggcctgctgtctacgagctgag aaccaggaaagccagtggaatacttcaaagtccaaaggccctggaaccaagagtgccagtgttggaaggcaggagaagat gggtgtcccagcttaaaaagacagtgaattcactctttttgctctacatagggcctcaatgggttggatcatggccaccc acattggtgaaggcaatcctcttagtctaccaattaaatactaatctctttggaaatactctcacagacacactgagaaa taatgttttatcagggtgatagaaatcttctggagttaaacaatggtgatagctgtacaatcacatacatttttaaaggg tgcgttttatggaaagtgagttttatctaaataaaatttctaagaaagagacttaacacagagataaacataagcacatt tattgtcaacctttatagtgttatgtcaaataggtctgacataagcttaaataaatatatactttaaaaattataaaata ttttaagttataatttaaaattctcaataaaactcaaacacaaaccacactggtatttcacacagctaatttctaatgca 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atcatagttgacagcatttacaagttttttaagtccctaccacacttgtattgaatgaagaagtatggaagattataata tattcaatgcaagtaaaaatatcacaatccttaagaactctttaagaagcactgaatcccatagggatgaaagtgattaa attgtgcatagtaaccctcgcacagagcattcagtaggatttgcaccattaacaaccctccatgcatttgcctgtgggca ttcaacatctgtcatttttttaagttataatatttttagtcatttttttcctctaaactctggataattattattcattc ttatgacagcaactgtgtaatcagctgtcgaaacactgtgaagggcaaaagaaagaaagccacaaaatattgtgtttctg tgccaagattttacagcgagcaagggagagttagaaaaggaattctgagatttcagagtcttggtctcttcacctttgct tggaagaaaatatcctttcccttcattagccaacactttcttgatcctgagagtaggaaagggaacactgagtcttttca gttgaaggccgtccttgcctgctggactttgatctattgaagtggtgatgggtgttgcggtttcagccataaaggcatct ggcatagtaggcaagaagggccagagacccgaggagagttatctgtctctgttaacttcagtgtatccctctagttcccc agatgcacctgtttctgtaaatataaacatgcatgtcatcagaacacttaatattctgcatactgatcatgacaacaaaa tgtaccttctaacacagacactctcactaggatagaccatgtaggaacatcgaattctattcagttaggacagtgatgat gtctacatattatacctctgtcaaaacctacagaatatacaacacagcacagagtgaattctaatgtagcctgtggacat taatgaataataatgtatcaatattggcccatcagttgtaacactaatataagatgttaataacagggggaattgaaggg gtggtggggagatatgttggaactctttgtgctttctgctcaatttttctgtaaacttaaaaccgcacacacaaaaaaag ttattttaattttttaaaaagtattcagagggacttgacctttccaaattctctcaaagcaggtcggagtagttaagaac acaaattttagaaccagactgccagagtttgaatcctggctacaccacttactagctttgagatttcagacaatttactt aacttctctgtctcattttcttcatctgtgtgataagaaataaagtaacaggccaggcccagtggctcacgcctgtaatc ccagcactttgagaggccaaggcgggtggatcaggagttcaagatcagcctggccaacatgacgaaaaaatacaaaatct ctactaaaaatacaaaaattagctgggtgtggtggcaggcacctgtaatcccagctactcaggaggctgaggcaggagaa ttgcttgaacgcaggaggtggaggttgcagtgagccaagatcatgccactgcactccagtctaggcaacagaatgagact ccatctcaaaattaaaaaaaaaaaaagtaaaaagaaaagataagaaatatagtaccagcccctatctcagagttcctagc ttagaaaaattcccagaatataataagtgcaatgtaagggtcagctatcttcattattattatctatcataaatgaaatt acacaataaagctagatccgtttctttcctctccttctacaaaaaataaagcaactttccagaacaatacccaggtgatg atttctcccctgctccctccctaagatattggcaagtttggagggttcaaggagaaacagagcatgtagagaagatacct ctctcataaccatttgtgatttacaagtcttacctgattcttttgaacttaaaggatgtaagaaggcttttggtagcttc catctgattcaaggctttggcagctgctgtggaatacatgagaacactaggtaaagcactgtcttccaacatgaagagag aaaaatatgtggaatgttcaatggcatgctttgtataagaatgcaacttacctggcaggaacaaatttctttgctgcaaa agaaaagacaaacaaccattaattcagactaaatgacttttaaggatatattaaatccagatacaatatgacttaattca tcaagtgttgcaaactcgatgcttcagggcctctgtaataatcagagcacaagcatggctctgtggcatctagggtaaaa tgcaaagtgcacagccatccaaagggcatagcagcttcctaatgccagcaaatagctacggggtcatcttgcccaattca gctcccaatttttcatgagaagtccaaagtcttaatttaaatgtgagatttcctattttgtaaacgtcagaacttaactc aaaaatgttttaagtactcttaaacatgtaagccaaacaaaccatgagtgtagtcagatgtgcttccatattccttatga gagactctcaaatttaagcctgtactccaaataaatctccttaggaagaattttatccattttccttagagtgctcatca tggcagttccattgcacaattccgggaggcatcatataattcaacatgaatagcaccccctggagttgtacaatattagg cacgactaacatttttatttcctgaaacacttcccacactgagttgtactactaactcttttcttaatacttctgcttaa ttatactgcattttatccagattctaattattgtttaaatcagtaagcaagaccatgacttatcaatgagaaagaaatgt attttcaaaaacatttttgaagtacattcataaacttcctcacctttccgtaagcatttccgaagccagaggagaaatgg tgctaatgtcaggagggagagtccagcagcagaaagtccagctaccaagggaatgttggactcagtgggagctaaggaag taagagacgaagaaaggtcatgaggaagaattgatgttaaagtctctccgtcctgtccctttggccttttttctgtacat tcattactaggagcagaagagctatctagtttaatacaagaagcagagatgtggcattacaggcctttgagatctgctcc aagccacctttgaagctatttccaccattggcaggcagaactctaacttgccaagctcgttcacaataccacaccacacc ttggttaataaacactgcacttgcttgctctcttgctctcactccctcttgttttccatttcccctttctcctctcctct ctctgtctcctttttccagttgtcagaattctaccctttccatcaacatgcaacttctgttttttctctatccccataca acttaatattcacaacttgtcaacctgggcgaactttctggtttggatataatgaatagttgattactgtaacaagatag ctccccctttttctttttaatcaccagacaaccaccatcaatcaatgcatcaccttcacaggtaggtagcaggccagacc agtgtcctgtggctccacatgtccgagctgcagagccattgagcgtccatccttcaggacaggcgaacttgcacacagtg ccaaacacgggctccccactgcagctcatgttgatctttcccggaactgccaggcttgaacattttaccactgcaaatgt taggtacacaggcagagtttcagaaaaatctactggaaaacttccaaaacttgcttaaaagtcaacaatgaatgtaaagt gtaagcgctacttagttttcagcatgtaggaaattaggaccaaacccctttggggcaatctaggttcagaaactttatga agtatttgacctgtaccctaaaaaagtctgcactcaattctaccttggcaggaaggaacctcttctgtccattgtccctg agatgtgcactcaagttgagttgatccatgtaattcaaatccctcctcacagctgaaggcacaagaggacttgtaggtga attctccaataggggaatgagcacacctcaccaaacccttcgggggctggtggacagcatcgcatctcacagctggaaca cacgagagagcactttagaagtttgtttgcatctccagcaatacgtttcccaaggtaaccaagttcccaagctcttcaat agttctttttatcttaaaataaaataaaaacaaagactgtaccttcacatgtgggcttctcgttgtcccactcccctgtg gggccacattggagccttttggatcccttcaacacaaaaccctgctcacaggagaactcacagctggacccataacggaa actgccagaagcactaggaagacaattcatgtagcctcgctcggggttggacaaggctgtgcactggaaagctgagacat caaaatgatggtcagaaaatattgcagtggaactagagagtacttggcgtttgttgagtgaacccagttcattcaagcaa cacttggagaactgaagattctttataattccctggacaaatgggaagatggctgtgttttctttgaatttcagccccct cactgatcatggcactaattaaaagactaattaatcagaacattagttcctgagcactgttcttctaacacacaaaataa attatggtccaaggaaagatttcacgcagtctgaggacaacatatgggtcatggatgtttatagatggtgccaaaaagaa agaaaagaaagcacccctataaaatttgtctgttttgcagtttggtttttgtgttatgttttgctactggaaatcattct gtgctggctttggctaggacaaggccagtgcctgatagtaaaaactgcttgttttcaatatccttgctctcactttaaag tgaattaaaatttactgcttatatatgcatcaatactatctctgtagctgacaccatgcttgaaacagtctcatcactgc taattatgagccatttcagaagacaggtgtgatgagagttttacattcaaatcatgttctcattattctgctttccgaat tttctaatatgattcctttagattaagaattctgtctattccatgctaatgtctacaaagttttatcagcacatcacagt taaaaaaaaacagcaaagaattcattcttaacacatatgatcctttccctggccaaacattagttcttttaaatgaatct caaagatacgagggttgctcatcaaatctgatttctatagttaaagtgggtattggttttttttttcactgtccaagttt gaagatggttgttctttaagaaagtataaatcgaaggatctcaagcttaccttcacaaactgggatttgctgtgtccact gcccttgagtggtgcattcaacctgggctggtccctgcaacatgaagccttcctcacaggtgaagttgcaggatgatttg aaggtgaactctccagcaggggaatggctgcacctcacagagccattctgaggctggcggacggccctgcatgtcacagc tgtaacaaatatacgcattgatattagcacggcctagaattagcttgcccatttccagtatgggttgagagaaagaatgt tcacagtaagtctccatgtggaacaactctacctttacacgttggcttctcgttgtcccaattcccagatgaggtacact gaaggctctgggctcccattagttcaaatccttcttcacagtcaaatgtacaggttgtgttccatgggaagcttccaggg ttttggaaacattccacgaacccattggctggatttgtcacagcatcacactcaaccactgaggattttaaagagcacca tgaattttacagaagaatgatcttttcacttcctattgagctgggtgcctaacagagtgaggaagctgccttcaaagggt agatcccaaagtcctatgtcaattcttagggacatgcacagccagaataaaagcttttattctttttcatggatattcta tcttttctgatttccactttgcctatgctgagtggtctctaatctatgttatcatttacgtgaggtaaaaatttaaaaaa aatagattccagattaggagttatgactagtactgacatacgtaggctattcatttattttagcccatcagagcctgaag aactgatttttctttttttggcctctggttcagaaagataaaattaagagagaaaaagagatactaagactgcttgacta tcatggtcttaagttagtcccatggcttggaaaagttaaacagggaaacaagatgagaaatccattgagatttctagagc tttattgttttatggtctcccttacaaatcaccagagcctcagaaacacccatttcaagcatagaataaaaaaacctctc tcaacccaagcaggtactgggttggcaatatacattggctgagagaacaaattgtattaaaaacaaaaacaaaaaaaaaa ctttccctgaagttttgaaaatgtaagttgaatcaaaaaacagaagcaatgagggatgagttacagaacgttctgtgcat tctcagagggatttaccattgcaggctggaataggagcactccattctccagaggacatacactgcatggtctccatgct gcttggcaggtaacccctatcacagctgatagagcaggaagaattgtagctgaagtttcccagtgggtgactgcaaacca ggcttccatgctcaggggattccagggctgtacagttcacaactgaaaaagaaacccaaatcagttctgctcatctctca cctttaacagataagaacactggaaactagaactacagtttggttttttttttttttagtttaaaaatttataaaatttc taatggaatttgtaaaattgactgtaattctaccccttttcttttattcaagaaaatgctgatccataacaacaacaaca aaaaagcagtgatgacaaccataaaaaagaaatattgagtgatatggggagagtagtgtaattgtgtttacctcaaaact gttcaaattatatgaacaaacacagcaaacttaggtaccacaacaaatttcttgttacttttctcacaactgctaaaaat actacagtaagcttccaaccaggatgagaaccattcacaaagctatatttcaaatttaagtactagaatacattacaaat tttaaaaccctaatgctgcactgtctactatagtagccactatctgtgtggctactcaaatttaaacttgaattcgttga aatcaaataacatttaaaattcagttcctcagtgtcaccagccacatttcaagtactcaataaccacatgtggctcatag gtacacactggaaaacacagctatggaacatttccattatcacaaaagctctactgcacaacgctgtgctaaggaatctt ggagagaagctcatctaactctcttaatgtacaaatttaggaactgagacctcatttcattcaagtgacttgctccatgc tacacggctagtcattacagagccagaggccagagcatgaaccaagataccctggactctgtaactcactcatttctact gcaacgtcttgttaccacctagatgaggtgagtacatgttcctcgcagggacacagaattacagtttattgaatgtgtcc tgtgtgccaggcaccatgtaaccatgagcctatgaagttcacactattattatcctcattttacaatgagaaaactgaca tagagagttaaactatcttgtcaaggtgccaaaataaataactggtgaatctaggactcaaacccagcagggtctgactt catagtctcagctcacgatcaccatatgacaccatctgcaccagggaagggaaggcatgcagacctgactctaatgccag ctaggacgtgagatggtgctaccatctcaagtgaagaaagaggcaagaaccagacttactttgctcacacttgagtccac tgaagccagggtcacacttgcaagtgtaattattgatggtctctacacattcaccgtggccactgcaggatgtattggta caggcagctacggaaaatacaaagcatgatgaggaggactattactgtgcttatactgagtgcctttgattttagaatca acagtgtgcaacagagacatcagcagtcctacagagtgccatagactttaactgaagtgttttacaaagttccaaatctg agtttcaggcccacctatcctaaaccttgatgctaatgtatagctgtggctggcacctaccgtagaaaatttacttcttc acaaactctgaagacagttcccctaccacaaataaacaagtaattaaaatatgtattgtgtgtgtgcatttttatatgta aagaactacatatttgcctacagtatttatatatattttatatatatacatacacacatatatgtgtgtatatgtgtgta tgtatatatataaaatgtatataaatgctgtaggctatatatatatacacacacacatatatgtgtgtgtgtatatatgt gtgtgtgtgtatatatatacatatccacatattcttgcccacattcacacaaaacagcaaaagagagaaactttagcagt taaacagaatcttttggaacataaaatgaccacaatagagagcagtttttgcatgctgtaaatttgccaagatgcccaca cactgaaactacctcccactgctgccgcaaactccctacctgtgtagcatagggcaagcttcttcttgctgcacctctca tcattccacatgcccacatctttttctctcttgatgtagatctccacgcagtcctcatctttttgcctattgttgggttc acctggagcccagttcttggcttcttctgtcagaggtttctgggttcctacccagacccacacattgttgacttttctga ttccaatccagtaataacttggtgaatagctcaatatggagtttaggtactcaatctcttctttgttttgaattgcaacc aggtgtgtgtacctttgctgacaataagcactggcctcatcataagtcatagcttccgtggaggtgttgtaagaccaggc tccactctctttaatgagaagcactagtgggagaaaaagaaaagaaatggtagagtttggtactgttgtggtttaactct gacaactgtgctttttattgtcttatttttggcaatgtttgtgacatggcccagacttttctcatcttttcaaaagtaag aagtacgtatgaagaaacagcgacttattgtttatctcttttgtgactgccacccactaggtaccttatccacactcact cacaacattatagtatacccattttgtagtagaataataatcagaataactaagctttattgagcacttagtatgcacca agaagcactgtatgaggtactttccatgaaccatgctattgaatcctcacaatgcatctgggaaataggtcattatgatc cacactttacacttaaggaaagggagacaccaagaggtaaagtaaatgaccccaagcccagggaagaacacattgcaggt agaggtcaaggatgctgccagatatcctgtgcaggacagccccagacaagcaaggatatttcagtctgaaatatctatag tgcgagaatgagaaatcttggtctaatggcactgacttacccaaagtgagagctgagagaaactgtgaagcaatcatgac ttcaagagttcttttcacccaaaggtttaggcttgaaatactttcctggggagataaaacacaaaatgaattaaagaagg aaatcgtgggtagctagttacattattctaccatgatgtttaaggcagcatcctaagattttgggcaaaggacactagtg caataatctttatttcagagtttaatcaaataaataaacaaattttaagactttcattatttaggtcaaagagaaaagac aggttttagctacaatacaataagagcttgtacagatgtggtttttattagaaggccttttgcatatctgtgtttcatgg cccgaggctgcccttataaagcgttctgcacttaccgttttgggaagcagttgttcaaacacaggatctctcaggtgggt atcactgctgcctctgtctcaggtcagtataggagttttgatgtgaagtcagccaagaacagctgaacactacttcggct gaggcccttttataggagggattgcttcctgtgaataataggaggatattgtccacatccagtaaagaggaaatccccaa tggcatccaaaaactttcccgggaatatccacgatgcttaaaattacaatgatgtcagaaactctgtctcttgaagctac ttcacctttgtccatgcctttatatcgtatatgcaattttattaatatgacaaaaatgcatgatttttaattataataac ataaagtctatgtctttaaaaagttgtaaaactttgcttgttagtagtgtctctcatgtagttgtggtagtaattagaat ttcagaaacagaaggaaaccaagaataggtttgtcatccatagtctactaccttcaatttctcattcatagctgtggata accaatcactactcattttttcttcctttttcacctgccaattcaacatatttaacatgcactgtctcacagaggaatga ctcacaaggtagatattaatcttcagattttgcacggcagttatgcctaaattaaaatattatctaaaaataatatctaa cactcaaatggttaaaataatgccttattttaaaaaaagaaaaatgggaaatagatatttacatctgggaaagtttcatg gtttgttcagtgaaaaaaataaaaaggaggccaggcacagtggctcacgcctgtaatcccaccactttgggaggccgagg caggcggatcacctgaggccgggagttcaagaccagcctgaccaacatggagaaacgccatctctactaaaaatacaaaa ttagctgggcatggtggcgcatgcctgtaatcccagctactcgggaggctgaggcaggagaatcgcttgaacccgggaag tggaggttgcagtgagccaagatcacgccagtgcactccagcctgggaaacgagtgaaactctgtcttaaaaaaaaaaaa aaaaaaagaaaagaaaagaaaaaaaataaaacggaaaactatatatatatatttaattggtcaaaattttgtttaaaatt tttgaaatgttaatgtgcaaagaataaaaattcttccacaatgttaacagtgactaactctggatggcaggatttgggat aatttttatatccttcattattattttcaggattttaaagtttttttcaatttccctttttttcacctttatagtaacaa gaatacagtttaaagaaacttgtctctaggccaggcatgatggctcatgcctgtaatcccagcactttgggaggctgagg tgggtggatcacctgaggtcaggagttccagaccagcgtggccaatatggtgaaaccctgtctctactaaaaatacaaaa attagccggggtgtagtggcgcatgcctgtaatcccagctactggggagcctgatgcaagagaatcgcttgaacccagga ggcagaggttgcagtgagctgaaatcacaccattgcactccagcctgggcgacagagcaagactccatctcaaaaaaaaa gaaaaaaagaaaaagaaaagaaaagaaatttgtttccaaatgcaacagaaggagatgtatgtggtatcctatattcctgc tcttcattttgacatttcttctgggtgattgtatacattccccatctctgcatcttaccctatctaaatgatggtaacag taaatggggatcattttaatttccatattctgtaggttttcagagctcaagtcaagctaatattctatatctacagcctt tcaaaataggaggtctatctaaaaatgtactgtcagcagacctgaacgagtagtggtaaaagcctcgtttttctctttac ttgttagcactggtctttctgtgttcataaagatgtcaagacccaaaaaaaaaacaagaaaagagaagaaaaattccaaa aaagacaactgattagaaaaaaataacttaattaacgaatttaattcaacccctatcaaaaagcatagaatttattccct ccaccttaccactctcttacatgatccagatactgacattattccaattctttatcccactttacttagctcaatgtggt tgttgcttcaataaattcagaagagtaatcactcatatagtgtttatttagattttagggcagaatgtcaagttgggtta atacattatctgtatgtattttatttttaataaagtatgaatacataatctgctatttttaaaaagcatggtcaaatgta tagagtagccaaatcttaaaaaacaatttatcttcgatatcaataaagtacctaataattatattgctaatagaaattag tcgttaacatccctagataactaactttattattgcgaatttttcataactaagtttatagtttatctcttccccttttt aaaattagttcaaagatatctaaaaatagccccagtggtgatgaagtttctattttacttacatatatatgtcctggacc cccaattataatctctaacatttattgagtgcttactatgtgccaggccatattctgagcattttgtatgttcacctatt gattattcaatccgtacaacagcctatgaaataggtactcctattatccccattttacagatgaggaaattgagaatctg gggattttatctcattcaaaagcacagagctaagggttgaaaccaggcagttgatatccagagcccactcccttacctgc tactccaaaccatgatttcttttgttgttatgccccgagattccttgttctacccaagtttcctgtactcttcttgccct cttcttcctgagacatccttgaccatcacagctctccactgagataactgtgtcctgggttctgagacatgggggctgga agggaccccagggacagtgagcagtagggagaggatgcagtgagaacagaccctggatccccggtgcataggcagggaga aagtggacaaaggaaaaaacaagcaaggcaggtggagccatgcctaggtaaagttgatccctaagccacagttcccagaa gttcctgattcaaaagcaaattttctctaaggtcaaagggcaaactgattattctaaattctaaactgattatttctaaa ttgagaaagcttcagggagagatcccaatattcgaaggataagagaaatgaggagtggaagagataggtgagtaacagta acttaaatgtagactatatataatatataatatatgtagagtatatatatataattacaatatattatatatgtggaata tatatattatttatatatatttatatattttatatatatagatatttttatattttatatataaatatagatatttttat attttatatataaatatagatatttttatatatattatatataaatatatgtaaaatactgtgaaagaagaatagaatct tgagacctcaaattcactatgccaaagggaaagttaagcttgggaaatgagtcatgcaaaaactgccttccttttgttcc caaatacctgtaatttcacatgcttactttatcttatataaaatgtagatgtactgagcatgagatccatgcataatttc cctctagtcccttctttttacatgtaaagtgtagactcactgagtgttacagagccttgccacaatgtaaacacttgtct cattgccaacccatctttcgtttattttcttcccctcctgcttgctctttcccctctaaagatggaagttcccaaaactc tctttggaaaaagcgcaggtcacagatcctacagtgatttgtgtttcttttacctgggacaaaataaacctctaatctgt tgagatatgcttcagttactttttggtttacaatatgtacatgtatgtatataatttatatgtatataatatatgtactt gttttaaccagaggtatgttattcaaaatccattcatccttacaattacctgcattctcccacagtattttctgtgtccc tgcccccgaggttgtcactgcaaatcaggtacatggatactgggagctgatgggctcccctctggctacctgggctgctg aaggggccatagacagacccagctttcctctcgtggagaggccctgggccagcgctgcgtgggagtgggattacaaccag actatagcttcttcacctgctttttcctatcaggatttcataagaggcaattgcttgttttttgagggtgggggcaaatc agggggagttgaagaggaaattgggtaagatttgaatagttgggcatgttgaatattatgaatatcatctccctcttcaa ataatccaaaatatacccccaagaaacaggctgattagaggtgcttcaaggctccactgaatctcccaagctctgaagat gtagctagctgttaccggattgccggttttcaagcctcgcctcacatggaccctcttggcagtttctcgcatgggggaag catccgctacatagatgggaatgaaaagaggaaagaagacggtgcaaactcaggcacaccccggtgtctgccaccagtgc tatttaatctctgaggtgtcacccttcctggctttattgtctcttcctggaagtctcttgtcctctcctccacacccttt aatcaggcatcaaagactttaaccagttttgctgtgtgcccaggcccactcattctcacttttatggcaaagggagtggg agacagagagatagccagaaagaagagattggggaccccaagacaaatgttagaattttaaccaaggccaccctgtggac aggagattattgggtttagtggaaagcagcactggccacaaccacacgtggcaaaagcatctatcgaggagtgaagttat atttggtgaatgtgaccgggaagcaggggcagtggtgtcctcctgccttcctgaggcactctgttcccttacctctgcga aggcttattttacccctgagtgcttagttttgaaagccttagttccctctctcccataaaaaagctctactctgctaaca tctaagttacctttgcagagtcttaggtagagggaggaaatcccaataaagattccaccctatctgcaaaatacaaacat ggtatttcttgcattcccaaaattgtgaaagaaaatgtgtatcaccacagtagagaatggcattttttgtttgatcaaaa cctaaatatatttgatgaaaatgtgtctggttctaagtttatttcccagaaagccatgtttactcacttggaatttatag acatcttataatatctgagtcgagtaggagctccgggctctacctcactcttttctcccacacccagggggaagtgtagg gttctcagactttagaataaagaggaatcacctggacaactcacctaaaatgcacatcttcaggtctcatactcagaggc tctgactcaacaggtctgggtggcgcccaagaatttgggctttaaatgagtatctcagatgattctaatacagaatgtgt aagatgaccagatcctatcacacttagatgtattggcctagggccacctaacttggagaaaatgttagtaagaccccgtg gttggtgctcagctataggtaccagaattttgatcaaaatttactatcattgtgacacttctcttcggaactggaaggcc agaaccccacttgtaaagtgctgggaaaatacaaggaaaatttagggtgagtagcattttgaattcttacacatggaaag taaatg ataagaattcttaccaataaaaaaaaagcaagagagaatagctgctaaagaattaacacaaatatgtatatat tagttattctcttttctcctctgattccagaggactttgtaattccactaattcttcttgagcttccaggatgatctgag acttgaatttttcatgtgctttttgcttcctatttggcagcatcttatcttgaagtttccgctttctgcttggggaccta aaaactaactaatgggaatttcttcaaaatgagcaaactctggtgaattcccaaagcggaagaaacaagtgaggatcggg ctggttaattaagagaacttttcctgaatgtagccagactgtttgccgactgttgttaacatgagggaagaaatacccct ggattttagaagagccccttgtttgttttccttggccatttgtgctgcttgttttgtaagtcagaaatttcctgaaggac tattattagctttgttctcacgtcagaaaacttctgctctggccacttttaaacatataacttggattttactgtattag aaaatgtaacaattacagacagcactaaaaggacaccaaagggcaaagaaaatgggtaacttttttttcttccccaaatc taaaataggtgattttggagaagtaggagaaaaacctggattttctagatctctttagagctcaacaactgatatagtta attatgtaagtctttgatatttggaaatgattggattaaccggataacaatgaatatttaaatacagtgatttggccagg agcagtggctcatgcctgtaatcccagcatttggggaggctgaggcgggtggatcacctaaggccgggagttccagacca gcctggccaacatggtgaaaccccatctctactaaaaatacaaaattagccaggcgtggtggtgcaagactgtaatccca gcaactcgggaggctgaggcaggagaattgcttgaacccgggaggcagaggttgcagtgagccaagatcacgccattgca ctccagcctgggcaacaagagcgaaattccatctcaataaataaataaataaatacagtgatttaacacaagagatttct atttcacactaatgagctctgtcactggggcaagcttctttgcctcattaagtctcagatttcccgagagcttatttatt tataccaagagtgctttactaccgtctctgctagctgtgacataatatgacaaaaggtataaatatgggaaaaggcacta atttatatcaaagcgttcttcgtttttccttgctgtgaagtttttagctaataattcataagaatataccatatttagag tgtttactatgcatgggcctggcacttcacatacattgcttcttacaaattttacaaagtgaaaggtagatattaatctc attttatggaggacaagatagagatctggagaggttacataacttgccagtgttttttcagttaataaatggtagggtgg agattcaatctgtgttactctaaagtccgtgtcctttttattggctccatgcctactcagatttaaatctcagcagggaa gtaaaccttagtttttacatgagaaaatgttacagcagccttctcggcttcctttacccccatcccagtttcacgagctt agtgccttagatcgggttcctttagaagcagacctcgaaataaggatgtgggtgccagtcatttattgaaaagatgatcc caagaaagcctagtaggagagtgaggaagtgagatggggaaaggaagaaactccacaagaagtgtgttaataagcaggtt accgctgtgggcagccatggggctcagctgcactaacaaactctgtctagtacagaaaacctcagggtctccccaaggag gggcaagaagtctgcctagggtatatatccgccaactcagtcactggctgagagctgatcctgggagggcatggttaatt cctctgcactttcaagtggattcctgtggtcagaaaaagccctctacaatgaattccagatgcttgtatttaaatctgac atgatctgaatgctgtgttgggacagggtgggcgttattagttttctgtcattactgtaacagattactacaaacctgat ggctgcaaacaacacatatttattatgtcatagtttgtgtgggtcagaagtacaggttagctcaactagtttctctgctc taggtttcacattgccaatatcaaggtgtcatccagttgggctcttcttgggaggcttggggatgaatccactttcaagc tcattcagattgttggcagaatccagttccttgtggttgcaggaccaaggtccctgttgccttgctggctgttggccagg agtcattcttagcttctagagactacctgtactctctgactcgtgtctccacttcacctttcaaaccagcagcggctagt cgagtccctctcttcaaatgtctccaactgtgccttcacctcatttctcctctgtgtaccatgtctgcctctactgcttg taagggctcatgggattacattggatttattcaatccaggataatctccatattttaaggctagctgactagtgatctta attccatctacaaagtcccttccaatagtactgtattagtccattttcatgctactgataaagacatacccaagactggg caattcacaaaagaaagaggtttaattagatttacagttccacatggctggggaagcctcacaatcatggcagaagtcaa ggaagagcaagtcatgtcttacatagatggcagcaggcaaagagagagagcttgtgcagggaactcctctttttaaaacc atcagatctcataatacttattcactatcacaagaacagcatgggaaagtcttgcccccatgattcaattactcccacca ggtccctcccacaacatgcaggaattcaagatgagatttgtgtggggacacagccaaaccatatcaagtacctagattca tgtttgattaaacaaccagggagcagaaatcttcaggagtggggggcatctttagaattctgcccaccaaggctgggcgc ggtggctcacacctgtaatcccagcactttgggaggccaaggtgggtggatcatgaggtcaagagatcgagaccaccctg gccatggtgaaaccccatttctactaaaaatacaaaaattagccaggtatggtggtgggcacctgtagtcccagctactc aggaggctgaggtaggagaatcacttgaacccaggaagcggaggttgcagtgagccaagattgcgccgctgcactccagc ctgggagacagagcaagactgtctcaaaaaaaaagaattctgcccatcatagtaggctgtcctacagagacataacccag gaattaggtgaatggctaacctaaattagcactgtgatgtgttttctgacttggtccttatagctcctctgcttagatgt ggaactaatccatgaatgcaagggtttgtctagagttttaagtgggagttaaatatccaaagtacaggagatattatggg tgcctcatccatgtccccttggcatttatctttcttggataacccaactctattagtttttatatctcacttgttcctat actctgtgaactgatgtcccataaatagacatttcattttgccagtcttcttgaacaataattacgattattaatctagc agttatcattaattggccacttcacattagacacagcacttaggacttaagaataccatgtcatttgatcatcataatat ggtcaggaattaagtattgctatccaaattttacaaagaaggcactgagggttagagtttaaataacttgcttaagatgt catagcctgtaagtgacaaaactaggactcaaatacaggtccatctgactccaaagtctatgttcttggctaccacactg cctctcctacaagtgacctgtggttttactactatattcacactctactaactttaccatctcccatgagtctgtctaga ggagggcacacacagcacagaaaacacatgaatgcaaaataaggaagggcctacttactacacagagccattctaatacc tgatgtttgctctaatccagttttactattaattagttgctggtgcccaagtttttactgagaaatggggataattttgg aagtcataatgatgccttcttctcatagggtattttatttgttgttgtatctccaggccccaacacagcctggcttttag taaatgatcaaaaatacctgttgaatgaataaatggagtcacctgaaacatgttaaacatttgttcatgtgtcctaatcg tggatttcaggatagtaagcatcctaaaaggaaagcatgcacactgttcttgctacattaatttctcacaatataaaaaa agaaaagcatctgaaaaaagctgccagccgctgtgtctcctaatatcaaactgagcacagatatggagaagctaagggag agggatgatgggccatgcctctaacctcatcatggcaaaagtcctgggggtcagacccgaggagagcaggaagtgtcttt tgagggatacatttccacagtggaaataatgagacttaaataaatattatatacacagttcaactgtttttatgtgtaaa ggtagtaggttttcacagtaaggaagcacttctttttttttttgtttgagacagagtctcgctctgtctcccagcctgga gtacagtggtgctatctcggctcactgcaatctctgcctcctggattcaagtgattctcctgcctcagcctcccgagtag ctgggacaacaggtgtgtgccattacacctggctaatttttgtatttttagcagagatgcggtttcaccatgttggccag gctgatctcgaactcctgacctcaggtgttctgcccgcctctgcctcccaatgtgctgggattacaggcatgagccactg cactcaccaagcacttctactgatagcatttacaaacccttcttagaatatttaaaaattctaagagaagagtaaattga gccttcccaactaatactaggaggttataaccttcataccaaaactggacaatgcttgcacaaaagaaggaagccaatga ggccacctagaaggaagactgggcattgggcccagtgagtcctggaaacctcatctgtgccagccaccccggcatggcct gtatgagtggatgagggtgacttgtccacagacaatagccatctagctgtgataaaggagtcaaggtagtcagctgcatc tctttcacctgtttgccaatgttacacaggttgaaaagctaaggtttatgtaaagcaagcatcaaagatgatgaaatgat caacctgacaatgagtactatgctgcattgtccagaaaggaactgtggaagattttgggctgaatttcaaaacagaattt cctcactctctggatgttggcttacttggcctttgatgttcagaggtggtgcctttgtgttgttgaacaatgttgatttt ggagagaaaacagagttgaaaaacccacaagtcattccctggggagtattaccggaatacagaggataatttcagcaagc cagcaaggcctcatctctgcttctaatagataggaagaaaggaagagaggaacaatacttttttaagaagctcagcttta tcgccttatctcatagaaagatgcctccagtctgtctggctaaaggtaattggcatgggaaagtctttatctgtgattct aacaagtggaatgtttcccttcattaagagagccttgtctggcttggggaaatgaaacactttctccgatatgagtgggc tgtaacccctgctactaaatactcagaagaaataaggcggttgtggagcagtcaggaatgagtcacttgcctccctggaa tattcagaaaactgaatcaaaagtacattcttctgggttttcttagtctaatagactaagggtctctactttgttaaatt tctgggaaacagcatagaatgggagaaaaaactggtcactgtagtcatgcaaatctgcaaaacaaacaaaaaagtctggg tattgctgctaactagctatgtgaccttaagcaaggtattaactctctctgaatttcaggttcttcatctgttaaatagc atatctgtaaaatgggaattattttcatatcataatgctgtagctttaaaaaataaaataaaatggatgagataatcaga attaaagagcctgggatatatagttaatatatagcagcatgtaaagatcctgttagaaatgctaattttacagttaacca tttggagatgatccgccaaagctgctagtgtagaggcaactgagaatttgcctgtccttcagaatatgaataaataactg tcaatgatgtctcaagcctagaaaaacctatccatctggatgggtgggaaatttctaggctagtattgagaagcccattt cttgggaaataggtcctggactgagtgaaggaaaagaaacagtaaaacccatggtaaagcagcaaggctctctagaggct ctggagaggatgaattgaattctagaagatgaagtagggaagacgctttaccttcttgtgaaatggattcaaagattcaa agaccttcgggaatctccaattgtataaatggcaccatagctgtatgttccatggaacactacttcccagagatgcccag tgaaaaaagaatgccacagtcaaataagtttggaaacactccattatgtggccacctccttgaagactctaatgcacatt agcatgttaaacagtcttgagaagtcctgcagagcagaaattgcttcacatctgctaagccggcagtttcccaatatact tgattatggatagttttttccttacaacaccattctctgatatgcttccaatgacatgaaataaatatatatgcatgagg ttcttcattagggcatactttttaatagaaaatattgagaataatctaaatataaatgcacagcatttaccttttctgca taaactatatacaggcataccttggagatactatgggtttggttcccacaatatctccaaaaccacattcggttttatga ccactgccataaaaccagccacatgaattttttggtttcccaatgtatatcaaagttacatttttactataccatagtct attatatatacaatagcattatatctaaaaaacaacgtaaacaccttaatttaaggctgtggctggtttgattttctacc cagaccactaaaactttcttcatatcagcaataaggctgtttcactttcttactattttttgtgatagcacttttccttt ccttcaagaatttttcctttctattcacaatttgtttgatacaagaggactagattttagcttatctcagtttaaggtgt ttacattgttagctaaaaatgctaatgatcatctgagacttcagcaagtcataatcttttgctggtggaaggtcttgcct cagtgttgatgtctgctgactgggtggctttggcaatttcttaaagtaagacaacaatcaagtttgacatatcaattgac ccttcctgtcataaatgattttttttttctctgtagcctgcaatgctctttgatagcattttacccacagtagaattttc aaaattggagtcaatcctttcaaactctggtgctgttttatcaactaagtttatggagtattagaaatcccttgttgtca tttcaacaatgttcacaccatcttccccaggagtatattctacctcaagaaaccactttctttgctcatctataagaagc agctcctcatccactaaagttttatcctgagattgcaacaattcagttacatcttcaggctctacttctaattctagttc tcttgctgtttctatctcatttgtgcttactttctccgctgaagtcttgaaccccttaaagtcactcatgagggttggaa tcaacttcttacaaactcctgttgatgttgatattttgacctgctcccatgattcatgggtattcttaatggcatctaga atggtgaacgttttcagaaggttttcagttggctttgcccggatccatcagacgaatccctatctatggaagctatagat ttataaaatgtatttctttttttgtgggggcatagcgtctcaccctgtcacccaacctggaatgcagtggcacagtcata actcactgaagactcaaactcctgggctcaagtgattcttccaccttggcctcccaaaacactggattacaagcttgagc cactgtgtctagcccaaaatgtatatcataactaatgaggcttgaaagtcaaagtgactccttgatccatgggctacaga atggacgctgggttaccagacatgaaaacaatactcatctcctcatacatctccttcagagctcctgggtgagcaggccc attgtcaaatgagcagtagtatcttgaaagaaattttttttctgagcagtagatctccacagtggacttaaaatagtcag taaactatgctgtaaacagaagtgctgtcatccaagctctgtttttccactgatagggcaaaagcagagtagatttggca taattctctagggccttaggatttttggaatggcaaattgagcattggcttcaacttttttttttttttttttttttgag acagagtcttggtctgtcacccaggctggagtgcagtggtgcaatctcggcccactgcaagctctgcctcctaggttcac accattctcctgcctctgcctcctgagtagctgggactacaggcacccgccaccatgcccggctaattttttgtatttta gtacagacggggtttcgccatgttagccaggatggtctcgatctcctgacctcgtgatccacccgcctcggcctcccaaa gtgctgggattacaggcgtgagccacagcgcccagcctgtcttcaacttaaagtcgccagctgtgttagcctctaataag agagtctgcctgtcctttcaagctttgaagccaggcatcattctcttctctagctatgaaaatcttagatagcatcttct cccaataggaagccattttttatgccctaaaaatctgtcgtttggtgtagccaccttcatcattgatcttacctagatcc gctggataacttaccacagtgtctacatcattacttctgcttcaccttgcacttttatgttatggggatggctcctttcc tctaacctcataaactaacctccactagcctcacattcttcttttacagcttcctcgcctctctcagagttcacagaatt gaagaatgttgggccttggattacactttggtttaagggaatgctgtggctggtttgattttctatccagaacactaaaa ctttcttcatatcagcaataagactgtttcactttcttactattttttgtgatagcacttttcctttccttcaagaattt ttcctttctattcacaatttgaccgtttgatatgagaggcctagattttagccaatctcagtttacaccatgcctttttc actaagcttcatcattttagctttttatttaaagtaagatgtgtgacccttcctttcatttgaacacttacatgatgatg cctggcttcaaagcttgaaaggacaggcagactctcttattaggggctaacacagctggcgacttttaagttgaagccaa tgctcaatttgccattagaagccattgtagggttaattaatttgcctaattttaatattatggtgtctcagggaataagg aggcctgagtagagggagggagatggggaaacagccagtcatcagagcacacacaacatttatcaattaagtttatcacc ttgagggcacaggtcatgatacttcaaaacaattacaataataaaataaaaaatcattgatcgcagatcaccataacaga tataatgataatgaaaaatttgaagtattgtgagaattaccaaaacgtgacacacagacacaaagtgagcacatgtcatt ggaaaagtggtgctgatagacttacttcatgcagggttgccacaaatactcaatctgtaaaaaattcaattatctacata gtaccataaaaacaaggtatacctgtttatataatcaagaccaacagaaccctagagaaaatagctcactccctagctcg gagacattctaaccaacatacacttacctttctttttgctgtgtacagaattcaaatccctgtctcagcaaaattgcaaa gtatcaaatgtcatgtccatctaatactcaaaactgcaaatgttaagtcttgtaagcccagagaccactgtatatacaag tgttgctataagcattagttcttctccaaagaaaatagtccacttggtagaaacaaacaaaaagaaaaaaaaagaaagaa aaaacattttttacaagaagattcagtctcttacctacataagcaaaaatatgagatgttctcttatcatttttccatct atcttataatctttggtgctgacttagacactcattttcctttttgtacgtgaccatgtaaaagttcaagtcaagaaaaa cttgttttgacatttgttttgctgagtgatgggtccctaaaagaaatttggctttgcttttgaaaagttcagcatgatat tgtgtgaatttttcatggctaatgatttttagaacagttgtgatgtgtttaggtgttttaagaatatgaagcattcagtg gtttaagttggttgttataaaatgaaagaatatgaaggaaagccttcttgtcttagaacacactgattcacaaataagca gcttctctcaaaatgttgtaattacaaaaattccaaggcaaatataataaactccttgtcggtgctatgtctagaaactt aacagccccaaagaaagtcctgacaaggcaaaaaatatatatatatatacaaattgtggaagcagggtgttgaaagaaga ataaagactatataaggacaaactgtttaaaagggagggtatccttgaaagcttgacacttgactcttttgacgaggctg agggaaaacactcagtttcatagattgctggtacggatgtaaaatagtgacatccctatagagaggaatttggcaatatc tagcaaaagtgcttatgcatttattctttgacctagtaatcccgcttctaggattagtggtgaagatacacctcaacaat aaaaatatatatacattaggttattagttatggtttaatttttaatagcaaaatatttaaaacaacctacatgaacaaat aggagacttactgaataaactatggtatatctgtacaataaagtgcaattcacttatgttgttaatttgttccaaaaatc cagagccaaagagtatttgttatgctctctttagtataagaaaggggaaataagatatgtgtgcatctgtttatttttgt gaaaataagtacagaaaggataagtaagaaactagtaaaactagttatctcctagtgttagtagaaatagaatgaaagtg aattaggcttctttgagtatatgtttatatatagttttgacttttgaattatgtttatgtttacatagtcaaaaatataa attaatcaacagaaataacaaaaaaagaagaaatcacaagctttaaaatttaatacaaacagaaataattgaatctaaca gtatatcaaagtgataacgtaaactcagaagaaaaaaacataatccaacataccagtggaacacaatattctaactgtat acattcagtggttatagtctaaggacaagaaaaattgcaaaaatatcttgaactttagcttgtaggatttttattggtag caatactaatgtactaattctgaaattaatgttcgtgtattatagaattgagtaaatgaataaatatgttgatgttattg ggaactaaaattatcattctgggagtagagaaatataaatatggacttggcaaatgaaacaaagacctgcagagagataa ccatataaactcattattttaaaaattataagtgtcctagctctgttactgaaaaggcctagattcaatcttatcttgat agacaggagggcacccctttctcagaacatggtttccaaatgccattctccattaaaaggaacaaggtcttcttggagaa aagactgattctaggtctggattaggtaaagtacaacgttagtctggaatttcttgctgaatcagaagtaagaaagtgct caaaaacatgggaacatgtcacaaacacacgtgaggcaacttgaatcctcactggccatatttaggacaatcgagcatca aaaaaaaaaaaaatgttgagaataatggattctaacacttaaaacaaaaaataatccatagcccacagaaggggaagaga gggggagctcttatttacagatgaatatcaaatagcaaagacagaagaaatgacagaattagagaaacatcattttgcaa aacaccactgtaataatcaattcaggcaagtattattaatggatgtattactattgcgtaaaaccagttggggaacagga tattcatacagtctgaaggtgtcaccctaaacataacttattacaagtggaaaatggtgcctttacaatgaagaaatcta gcagaaaccatcttaatctagtgatcaaacttagtatcaccaataatggatcatactgagtcatgtgtctcctaatatga tgcaccaggaaggatgcaacgtcatgaacgttgtattcttttgtattcaacagaccacccagggtaaaggcagctttctc acttactaatcagaattgttggttttaattcattttggattttaagatttcttactttcttgtcagctcagaaatttatt taagatgatttttatcttttattcaatactttagcttggagaaccattcagagtttctaactcattgtattgccaaaaat agaaaacagcatggtttcttttgaaaatgtctaactttaaagttacttgtgtgtgtcactcagattcacatagctttttt gcctagtaatgtagtatcatgtggcaaggctataaaaatgtttacaatcttttatttaatatgactcttgagagtttatt ctaaggaaataattgaatagtaacaaaacactattaacacaaagcatagcaatttgatttgggcaaccaaacactggaaa caacctaaatgtccattacaggaatcatttatgaagcaaacactaaaatatttattgtgaagattatgagaacatagaag acagttatgagagtaaatttgaaaacctgaacacaaaacttacatatactccaattgtaacttataaaaaatacgtgcat ataaggataaaacagtacaaacaaaaaaatagttgcgttagattggtagaattatggctccttttgctgtcttaattttt tccttttacattttgatacattattttaattttaattttaaaattcaaaagaatttgccactcatctttgccacttcaag gaaaaaagaaatgtgttcgattattctgttcttagtatagttttggcaatttcctcacgtgtaaaaagagaatactatta ataatttcagtatctataagacaatataaaattaaagaatctagcccagtaactggtacatggaacgtaattaataaatc attatggactttttttctcacacccaagtagggaggaatcagtggtcccctagaggcccagtgtagaggtggcagcacca atccctaggggagaagatcttggtgatgataattcctgagcagacagttagctgagaattcaagagcagaaaagtaagaa agaaacaacttcttgctaacacctttccacccacgtttccctgttctgttgtactctgcttaccctttcatggatggagg cagaggaaagagaaccaagtttgctcttagtcattcactatgttgtttaatctgccttccatctttcttatcagttcaaa ttagaatgtagacctgaatttaaatccccgttctgtcagttataatgtgaccctagacaaaacacattctctgaacctca gagaacattcttcatttgtagaatgggaagattaatctatattccacttggatggcaagtcttttataaactttataacc taaacatgtgtgagttgctagtatcattatgttggtaaagttattctgagatatgataacagaactgttttgtctaactc cactagcatggttcaggtttagagagtgtggaattaaaaggctttatcctcaaatatgacttaaatccgatttttctcat ccactttcctccacaaacaaatcctcaggaaatgacaaactttacatggttaaacatcagttttgtttagtctttgacat ccacatggttaaatcatacatttgaaaactgcttatatttgtgttgtctatgtctaaattgaaaagacttattgaggaat agaagactacacatttttcagcaaacactgcacgttttgcagaatttccccaggcaccagtctccaggaatttattggct actaacaatactaagatatggatgaatgaggaaatcaaaatggagatcttgcaagttttgtgagaatgggtgaatggtcc aaatgaagagataagttgtgaaatattagtacaagtaaaaattatttacaatgaaagacattttgtcaatagctatgaga attttaccattgacccagaaattccatttctttcttcagaaatacccacgtaggtatacatataaaaagttattcattac agtatcgtttttcataggaaaaagttttaaaaatcagaagctatctaaactatggtatatctaggtcatagaaatcaaat gactaaaaatgttaatataagcatatgtttttaaattaacttggcttgggtcttcagcaaaattggcttcttaacattgc actccagagttagacttacccactcagtcacttatcatgcaggagcagactcctaataccacatatcatagagcagagta ggacacaggttctctgcaggcaggcaaatcccaaagagaagggaggaaagggctgagacactgcatggtcaatttcttct gaactctgcaatgtacggaggtggacagtgtccacaaagattgctcccctggacccaccatcataataacacaacggctt tgttttgtttttgtttttgttttttgacacggagttttgctcttgttgtccaggctggagtgcaatggtgtgatctcgac tcaccacaacctccacttcctgggttcaagtgattctcctgcctcagcctcctgagtggatgggattacaggcatgcacc accatgcccagctaattttgtatttttagtagagacgaggtttctccacgttggccaggctggtctcaaactcttaacct caggtgatccacccgtcttggcctcccaaagtgctgcgattacaggtgtgagccaccgcgcccagcccacaatggccttt tgtttacatctctagtgcagcactcatttcatgttctttcaagaagaatacatatttcatctttttattttatacagcaa ttagcacagtgcctggcataaggaaaatgatcattaaaagctgggtgaaaaacctaataaagctactgaggataggaact gcagaccagcatggaaagaaaactatgagccagatattgacatcatcctgaaaggcagaagatttagtataggcaagaag tatgcttttggaatatagaaaatctggattatgataagaaaagaatcatatttgtcttatcttacctactcacttctcag ttccacatgtttctgaggctgtttgtccttactttcttttctgttttatccactctttctgttctttagattggatcatt cctattgagctgacatcaagttaactgaccttttattttgtccaaactgctgttaaatgcatccagtgaatttttaactt tatatagtatatcttttagtcctagaatttccacatgagttttttaagtttccatttctctgctgagatctcctatttgt tcattcattatgaccatatttttctctacattattgagcataattataacagctcttctaaaattcttgtctgcacattc taacacctgaattattctggggtcagtctctgttacattgccttattacaaaaacagtataagtcacattgccttgtttc ttaatatgcaaaatgatttttgattgcagactagacattttgaattaaacattatagagattctggattctcgagagagt attgacttgttttttccatcaggcaggtaacttgactggactcaaactccaaactctaggtcctctgtaatgggcaactg cagtaatctttgtttagttctttaagacttattggccaggcacgggggctcatgcctgcaatcccagcactgtgggaggc caaggtgggaggatcacctgaggtcaggagttcgagaccagcctggcccacatggtgaaaccctgcctctactaaaaata caaaaattagccgggtgtggtggtgggcgcctgtagtcccagctactcagaaggctaaggcagaagaatcacttgaacct ggaaggcagaggttgcagtgagccgagattgtgccactatactccagcctgggtgacaaaagcgagactccctctcaaaa aaaaatttattggcactgcttggcatctgctatgaatacatgaagttcatgggtcagctatagatctgggcacgttatac acagaatttgggtctccctttctctggatttctccttttctggatttcttttctcattttccagcagctgtggttgccct aaactcggtcctctgtttctttacggcagtaagatttgggaacttttaggttttacctgcctctcagacaaaataaaaaa taattttcatcttgatgctactcctttcttccagatgtagacacctctctaatttccagttgctttttattgctctccag agtctaaagattatcattgttttctgtgggagagttggtctgataaaaactactcccccaaaactggaagctggaagctt gtaattatgaatagactttgagtagtattcttctttggaaaaggattttaactactccctatgtacttctttatttcctg tttttctcatccgtaatctttttattttcatacttcctaagtcagacaattttcctacttgaagattcagtgactgctat caaatgacccccatattactaaatacaatatccccaactgcatttataaaaagaaaatttactgtttattagtaaacaat gttgtagaatagtaaaatattgctgggctttggagccagataatcaaggttagaatcccagattctaacttactagctgg tgtattagtcctttctcatgctgctaataaagacataccccagactgggagactgggtaatttatgaagaaaagaggttt aattgactcacagttcagcatggctggggaggccttaggaaacttacagtcatggtggcagcaaggagaagttccaagca aagagggaaaagccccttataaaaccatctgatcttatgagaactcactcactatcacgagaacagcatgagggtaactg ccctcacgtttaattaccttccaccagttcccccccatgacacatggggattatgaaagctataattcaagatgagattt gggtggagaaatagccaaaccatataattccacccctggcccctctcaaatctcatgtcctcacatttcaaaactcaatc atgccctcccaactgtcccccaaggtcttaactcattccagcattaagtcaaaaatccaagttcaaagtctcatctgaga caaggcaagtcccttctgcctatgagcctataaaatcaaaagcatgttagttacttcctagatacagtgggggtacaggc gttgggtaaatacactgattccaaatgggagaaattgccaaaacaaaagagttacagaccccatgcaagtccaaaaccca atagggcagtcattaacattaaagttccaaaatgatctcctttgacttcatgtctcacatccaggtcacactgatgcaag aggtgggcttccaatggccttgggcagctctgcccctgtggctttgcagggtatagcctgcttcctgtttgctttttcac aggctgacattgagtgtctgtggcttttccatgagtatggtgcaagctgttggtggatttaccattctggggtctgggcc aggtgcagtggctcatgcctgtaatcccagcactttgggaggctgaggtgggggatcacaaggtcaggagatcgagacca tcctggctaacacggtaaaacccagtctctgcttaaaaaatacaaaaaattagccaggcgtggtggtgggtgcctgtagt cccagatacttgggaggctgaggcaggagaatggcgtgaacccaggaggtggagcttgcagcgagctgagattgtgccac tgcactccagcctgggcgacagagcaagactccatcaaaaaaaaaaacaaaaaaaccattctggggtctggagaatggta gcccttacagcaccaccaggcagtgccccagtggggactctgtgtgggggctctgaccccacatttcccttctgcacggc cctagtagaggttctccatgagggttctacccctgcagcaaacttctgcctggacatccaggcatttccatacatcctcg gaaatctaagccgcggaggttcccaaacttcaattcttgactcctgtgcacccacaggctcaataccacatgtaagccac caatgcttggtcagggcttgaaccctctgaagcaatggcctgagctgtacgttgacaccttttagcctagacatctagga cacagggcaccatgacccgaagcttcataaagtgggagggccttgggactagctgaggaaaccatttttccatcctaggc ctccaggcctgtgatgggaagggcagccatgaaggtgcctgacatgccctggagacgttttccccattgtcttggtaact aacattcagctccgtgtgcagcaccaacttacttatgcaaatttctgtcactggtttgaatttctccccagaaaacagga tttttcttttctattgcatcatcatgctgcaaattttcaaacttttatgctatgcttcctgttgaagactttgcggctta gaaatttcttcccccagatacccaaaattatctctctcaagttcaaagttccacagatatctaggggacaaaatgttgcc agtctctttgcatagcaagagtgacctttactccagttcccaacaagtttctcatctccatatgagaccatctcagcttg gacttagttgtccatgttactatcaacattttggtcaaagccattcaacaagtctctatgaagtttcaaacttccccatg ttttcctgtcttctaatagccctccaaatttttccaacctctgtctgttacccagttctaaagtcacttctacatttttg ggtatctttacagcagtggcactccccatggtactaatttactgtattagtctgttctcatgctgctaataaagacttac • tcgagactgggtaatttataaagaacagaggttcaactggctcacagttcagcatggctgggaggcctcaggaaacttac aaacatggtggcagcaaagagaagttccaagcaaagagggaaaagccccttataaaaccatcagatcttgtgagaattca ctatcatgaaaatagcatgagggtaactgcccccatgattaatttacctcccacagggtccctcccatgacaggtgggga ttatgggaactacaattcaagatgagatttgggtggggacacagccataccatgccagctagagagccttaagaaagtca cctaatctccacaaataaaaggtttcctatttgttcaacaaaaataatgacaccccttttatgggatttctgtgaggaca aatgataactaacatagccttgcatagtgtctggcacaaaatagctactcaaaaaataatagaaacaacatttaaaaaat gtagactttattttttagagttttatgtacaaagcaaaattgagcagaatgtacagagagtttccgtatagcactcccta cccccaagcacagatagcctcccccagtatcagcatcccgcaccagagtggtacatttat ataactgatgaatctatat tgacgtgtcattttcatccaaaatccatagtttatattagggatgcctcttggtgttgtaccttctatgggttttgacaa atgtataatgacatgtattcaccattacagtatcataaagaatagtttcactgtcctaaaaatctttgatcttcttccta ttca cactccctccccattjaatccctgacaactactgctaattttcctgtctccattgttttgtcttttcctgaatgtc atatagtttaaatatacagtatgtaggattttcaaactggtttatttcacttagtaatatgcatttgatgttcttccata tcttttcaaagcttcatagttcaatatttatagaattgaataatattccattgtctggatgtactacagtttatgtattc attcacctatcaaagaacaccttggttgcttccaagtttcaacaatcatgagtaaagctgctataaacatctatgtacat gtttttttgtgaattgaacattttcagcttttttagctccattcctaggagtgcaattgctggattgtatgataagggta tgtttagtgttgtaagaaactgccacgctcttcctaactggatgtactgttttgcattctcaccagcaatgaaagagttc ctgttgctccacatactcaccagcatttggtgtcgtcaatgttttgagcaatagcattttgatctaacttttcctaggta ttctttttgaaggaaataatatgacagataatagagaaaggatatacgaggacagttctgtcctttatttatagtccatc atttaatgaaggactctgtccacacttggtatttttaactctgatcctcctctcccatgaactctgacaatctcctaaat ccctgttgctggcacacatggttgtgtatcaggccccctgtggtctgtctgaagcatggctttttttttttttttttttt tttttttgagacggagtctcgctctgtcgcccaggctggagtgcagtggcgcgatctcggctcactgcaagctccgcctc ccgggttcacgccattctcctgcctcagcctcccgagtagctgggactacaggcgcccgccaccacgcctggctaatttt ttgtatttttagtagaggcggggtttcactgtgttagccaggatggtctcgatctcctgaccttgtgatccgcccgcctc tgcctcccaaagtgctgggattacaggcgtgagccaccgcgcccggcctttttttttttttttttttttttttgagatgg agtctgtcactctgtcacccaggctggtgcagtgatgcaatcttggctcactacaacctccatctttcaggttcaagtga ttctgccacctcagcctcccaagtacctgggattacaggtgcccgccaccacacccagctatttttttgtatttttagta gagacgtagtttcaccatgttggccaggctggtctcattcctgaccttgagtgatccacctgccttggcctcccaaagtg ctgggattacaggcatgggtcatcacatgtggcctgaagcatgactgttgctttaatcatatgaaatactgctctgtatt gttatctatttgaaatgccacacctcctgagctaaattgcaagcttttatggagcacaaaccatatttatatatattagc atgataccatgacacatatcaaaagctgttatatattgttacgtgaattgattctttctcagttaagaggacctctgtag tagcactttcataccgttaatttttcattttgtgcccagcccctactctgtgaaaaatgaaatgaatcctgttatcattt ccctcccaggccttttctccttgtggacaatgtgtggctcaagagaaaattcagtcagtaaatttgttcagtgcacaaac tctttatcacctctcactgttctcaagtgagatagaacagaacatccatccagtgtcttacaaattgtctggtatatagt aggcactcaataaatgttttttgaataaatgcatacatgaatcctattcctatatatagtatggtagacagatcattgat acccaaagatgcccaaatgctgatccccagaacttgtgaatatgttacatttcatgtcaaaagggactttgctaatgtga ttaaggattcagacccttggattgtaagattatcccggattaaccagggccaatctaatcacatgagaccttaaaaaagc agaaaacatttcccagctgggttagagagagatgagacagagtaaaaaggaaagagattcagggcatgaaaatgactcta cccactgttgctggctttgaagatagaggaactaggccacaaaacaaggagtatgagtggccttaagaaataggaaaaag ccctcatctgacagccagctagaaagcagtcctctgaccacaagaaattggattctgccaaccactcaaatgagcaagga aatggattctcccctagaacctccagaaaggaacacagctctgtaatgccttgattttagccaggtgagacctgtttcag acttttgacctatggaaatataagataataaagttttattgtatgctgctaaatttgcggtagtttattactgaagcaat ggaaagccaatacagacagaatatacagagagaaagagaatgagttctttcctgataatttgtaaatatttgggtcttca ctggacaagcttcacagaggattcactggttccctagcaaaccagcatgtccagtcctgcagcctccctttcttaggccc agcatatgtcagctgtgtgcatagaaaaatcaaagcaggaccctgagtagttggaaagaaaagatggttggaaatgggtt gcacttcaagtgaggaaacaagaggtaggagaccggcatctctttctcatatgtcccaggctgactcttgtgagttgttt tcccttggaggctatcgatgacagtcacagtaacctgatggaacctggatcatgatgaaagaagtaagtgtcaatggctc cgacttccaaggactctgatgtcccacagcactagctaaacaaagccagttggaaatgagcttaaatggggaatttcctg aatatattccctattgttaggaagccaggttggcttccttgcctacaattatgccaagcagtcacactatagagtcccta gggacatgatattaagtgattcttttaacacaaacaacttaataatcatttatactaatagcaaaacggccaacggctga tattccacttgaagtagaattggctatccaactggaagagaagacaggaagacgtgatctccagggagccactaaaagga ttggcacctgcctctggattccccttttccttatattacctctcagcactggcaggcctttatttcaggatacagtttca caagtattatgtcacgtctctgagaattatgttggtagatatttgctcctctggccagaaagacctagtttggagtctgg agtcatgaaggtgacatacatgtagctagtgacataagtgtagctagtaaaaatagtgagtaatggccctgaaattctat tgaatgcccaaagtgctgaccaggaacaagcatgctctagcttatctcacaaggaacttgacaattttcttcaaaaatcc tagtagctaagatttcttagtaacaaagccactaaggcacaattatgattaacttgacccttaggtgacttttaaggact attctataaaatattacaactaatagtggatccaagccagcacactctgctatataagattaattgacagtgtccacact ggtaaaataagttgtttcataaatacattagaattcatttgcactttctacacagccccaagtccagaactttccccaga ataggtctatgttttgcaatctgctactccatacagagatttgagttcacttggcaatttagtgctgcttatatgtgacc agttagtctgttttacttatctatgccttaaacattactatacttactaactccaagatgcctggtctcaacttgacaaa aataccccaagttgggaaatccttatgtgaatatgtagatagtcacaattgctggttgatgatgatctgtcttttcctgt atttgagaaaatggagataaaatggaccaatccaaataatggattaaacatgggaataggtgagagagagagaggaatac atggtggctctcagtgtctggcttaggcagtaaacactttcgttaataaagacggaaaataaaaaaggaataattggtgt ctaggggaaaataatgagctcaagttttaacactctgagttcccggatgtgagacatccaggcgcatttatccaagaggc agttggaagcaacgttccggagcttaggagagaggcatgaccaaaagctggtgggactgtgaaaaggtatggccattctg gaaaactgtttggcagtttcttagaaaattaaacatgtactaacaacccagcaattgtactcttgagcatttgtcccaga taaatgaaaaaaaaaaaaagcattttttttacacaaaaacatatacatgaaagttcatagaagtgttattcataaaaaac tggaaaaaactgagatgtctt attgagtgaatgcttaggcaaacggtggtctatccatacaatggaattatgcttagca ataaagagaaaagaactattgatacatgcaataacacagatgaatctcaaaggaattaatgctgagtgggaaaaaaagca catctcaaaatggtatatactgtactattttatttacttaacattttaaaaatagcaaaatcatagagatggagaacaga ttaatgggtactgtgttttgggatggggagtgagaaaagggtaaggtgtaaatataaaggggtagcacaaaagagccttg tggttgaaggattctatgtcttggttgtagtcgtgattgcaggaatctacatgtgataaaattgtatgggtctacatacg catacacacaagagcatataaaactggtgacatgtgaagaagctccgcacattgtgccaacatcagtatcctagtttcaa tatcagactacagttatacaaaacattgtcattgagggaaactgggtaaagggaacacaggacatttggcatatattttt gcaatttcctgtgaatccgtaattatttaaaaataacagatatactacatatcaaaaatttaatgtcataaagttgatga gtttacctagtggatagctttgttaatatctgctataagactactgaaaatgacagttatgcaagtataagctcagagaa ctttcctcccccttcgtaaatgaaatgagcaaaagaaatgaaacaggaaaggcaagcagtactgaaaacagggaagggct cttccccatataactatatctgcgacttcaacagctattcatccagaaacacagcctcttgcgctaagaggaaactttgg ataacaatatgttttcactctccaagagagaaaatggatagattaatttttaagaaaaaaaaaaaaacctcaccaatttc atgctgtggcttgcacctttaatcccagctacctacaaggctgaggtgagaggcttacttgagcccaggagttcaaggct gcaatgagctatgattgattgtgctatcgcactccaacctggagtactaagctaagagctaagaacacagctgagagcgg agaagaaacaaacaaatctgaccaataacccccactcccctcattttactggagtgagctgagactgctggcaaacatgg cctttgacctagcctgaactgtagcaaaagtcatcagatatttttccaccaatcaacagacagaagtggggagaaaacaa tcgtagttcataactacaacaagcagataaacgaaggccatggtgagggatggaagacattgtgatatatcaaaggcagg ctcatttaaaactcaacccaaattccaaacaaaatatataattgaatatgtattaatgccaaaggagcttgagtgagctt tagcacaaaccccgccctccagcccccacccaaaaaaatcactctgttctctccccattctttgataggcatacttgctg ttttctcacagccaaggtacagaggggacttagaggaactagaactctaatacactgctagcaggaatgtaaaatgaagc atctacttcagaaaaccattttatcagtttctagaaagttaaacatagacccaccatgcagcccagccactctactccta agtatttacacaagagaaatgaaaacgtgtccccacacagttgtatttaaaggtgatggttagccttgtgtgtcaacttg gctaggctataatacccagttactgaatcaaatagtaatctaggtgcatctgtgaaggtattttgtagatgtggttaaca gctacaatctgttgacttcaagtaaaggagattgctcttgatagtatgggtgggcttcatccaatcaattgaaggcctta agagcaaaaagtaaggtttcccggagagaaagaaattctgcctcaagactgcagcctcaactcctgcctgagtttccagt cagccagccagcctaaagatttgctaggcattataatcacatcagctaatttcttaaaataaacctctttatatatattg atacaatgaatggttatagcagccttatttgtaatagccacaaactggaaacaacctaaatgtccttcaataagtgaata cataaacaaattgtggtata ccacaatttttacgcagcagtaaaaaggaataaatggttgaataaggaataaacacata acaaggatgaaccttaaaaccgtaaggctgaatggaaaaagtcagacaaaactaatacatactgaataattccatttata ttgaagttctagaaaatgaggactaacctatagtaacaaaaagcagaaaaattttgcccactggtgatggagggggcgca ggtattgtagagtatctgagaaaggacaactggataaaagggggcacaagaaaacttttgagggtgattgatatgttcat tatcttgtggcatggtttcataggtgcatacatatgtcaaaacatcaagttatacacttttaaaatgttcagtttactgt atatctattatacttcagtagagaggaaggaagaaagtgggcagggtgggggagaggaaaggaaacgagggaggaaaggc cctaataggaaggattttggagtttagattttaaaatgataaaggatgtttgacactctaggcatatgacgaatatagga ttatgagtccacaaaaaccaccaggaagtcatgtatgtttatacttttaagtgaaggatcagtggattatcaactcccta atgctttgcctctctatgactggctgctgtccttctcatcccaatactccttccaaagccccttgcttaaatgtaagcct tctttcctcctttcaacacatcctgcattccgtgacaaaataagttttccttaaacagaatgtacagcatattatttgta caattaaaaatttttggccaggtgtgatgactcatgcctgtaatcccagcaatttgggaggccgagatgtgtggattacc tgaggtcaggagttcgagaccagcctggccaacatggtgaaaccctgtctctactaaaaatacaaaaattagctgagtgt agtgtggcaggtacctgtaatcccagctactcaggaagctgaggcaggagaatcgcttgaacctgggaggtggaggttgc tgtgagcagagatcagactattgcattctaggctaggagacagagtgagactcggtccccaaaaaaaaacacattttttt ttaatgtttcctccttgcctgtaggaaaaaggctctgactccttagcctgggcatcagagctctatctaaatggacttta acctgattttgtggcactaattccattgcagtacttgtccgctcactggcctgtgcctctctgccactatttttggaata atgtcctctctccatcttgtttactcaactatatccaacctctaaggctgtgctcctacaaagcctcccctggctacttc agcccacagagatatttaactgctctgcagttcaggacattcttctgactctttaaatcacatttacttatatatgatct tgtgatattttttgttgacgtgtttactttaattttcttccataacctattcattcaacaaactcaacaattatttatta aatgccaagttagaaaaatattattgattttatatagattatagatatgtttgaaattttatttggcaatctgcaagtag aaaaataattataatgtggtatatctgtgatagaagtattagtgcagagaccatggggaacataatccagcctggaagtt caggagagatacgtggaagaaaggacgtcagagcctttttcctacaggcatggaagaaacattaaaaaaaattttttttt ttgagatggagtctcactctgtctcccagcctagactgtggtggtgcgatctctgctcactgcaacctctgtctcccggg ttcaagtgattctcctgcctcagcttcccaagtagctgggattacaggtacctgccacacatggatgataaatatgatca tattttcttgttcttttcctcctcagttgtcttccctgaagaaaggaatgccttttatagatgacaaactcccattctca agaacaaggatttttgaccaatttaatttaatcagatgtctggctttgacctagaaacacagtcacgaaacttggtgatt agagaccaattcccaaacatgagcatttcttaggaaacacagtaaagatctgagagacccaagagcagaagggcgagaaa ccaaaagccatcagtttgcataggaaacaccttgtttagcctaatctttttatttttattactctattagtcactacaac tattttctgattgctatggtgatagatggtttaaaacaagccttcattaagaattgtcacaccatggtctcagtcaaaaa caccaacatttttattggtattgacaattatgggaatatccaattccaagaagacaaggagacctctgaactttctaaat gaagactccaatcttcctgatctgatgggaagcagcttggcaagattaccaaccaccaccacagagagtggactctaagc taagacttaaaagataagtagaaattatccaggtaaagatgtgtacagagaaggaagtacatccaggggaaaagaacaat acgtgcaaaagtacggaaatggtaaaaagtaatactacatagtcaaagccaagcagagttcagaagggatctggtggtga aaaatacggctagagaaagcagcaaggattggcttctaaaacctatgtagtatcttggaccttaccctaaatgtaatgag 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tcaaagataacctaaggggagaatgctgtctggcccaacagcaggctctcgacttcatttcagacactgtggccaatggc tgggaaacaggtatgaacagtaggtttctgagtcccctggaattattccatttatgtagccacctccatgacaggaagcc tccctactcttacttcccagtttgttcattcatggcaccaggttgcagattaaaatttgctcagtgaccttttatctaat aatgtgttaccttcttctcttaaaaagtacaagggacaaatgctcatggtatacttttaggagattgtggctctctatta acagtatttattcaacaaacatttattgagcatttatatgtgcatcatgctagggactggaacctagtaagtgtagcaca tattatttcatttaatcctcacaacaaacccatgaggttggttttatgatcccaatttttcagaagaagaaactgatatt cagaaccagttaactaactggttcaaggtcatgcaatttctaagatacagaaccaagagtcaaagacatgattttaaacc aaagctttttctgctactccacattgcttccctaggtgagatctgaggcattccgcgaaaagagaagggtcataaagcca agggaagacaagcttaggaaaaaaaagggaaatgtcctaaataaacagctttcctatttaccagaaaccactagtttaaa aatataatgggaaaaatcctattcactttaacaatgttaaaaaaaaaaaagatagaagaaacatagggataaacttaaca catttgtaggatatgtaaagaaactaaaagatgttaataatggcctaaagaaaaaaaaacttacatgtatggggagatag accatcttactggattctaatatttaatagtctaggtgttccatttctcaccaaattaatgtatacatttaatacaatgt caaacgaaatatcttaggaattgcttacaaattgtcagataattacaaagtttacctgggaaatataagcatatatgaag agtgaatgggaccccaccactccccccaaaacaaaaaaggtctgaaaaggacagaaatcaaggagagtcttgcctgccag atacaaaattctattataaaggtgtattgatgaaaacaatttaatactagtgtagcaataggcagcaaagcaatgaaaca gcataaaaagaccagaactatacctaattatgatgaagatttaaggtatgataaacatgacataattcaaatcagcagaa attggcatagatagggttaagacaaatagctaatcattagaggggaggaaggaaaggagggaggataaaattaggttcct gccttcatcttacattaaaataaattccagatgtattacatttaaatttttttaaaaaaagaaaccacaaaatacttgaa gaaaatataagttgttatatagtcttttgatgggaatttttttttttttcagagacagggtcttgctctgtcacctagcc tagagtgcaatggcatgatcatggctcactgcagccttgaactcctgggctcaagtgatcctcccagctcagccccccag gtagcaggaactacaggcatgcgacaccccatccaacttattttttattttttgtagagacaggggtcttgctttgtttc ccaggcttatctcgaacttctgccttcaagcacctcagcctcccaaagagctgggctgatgggacattttttaacatagt gccacattaccataaatgaaaagcttgtaaaatactaatttttaaaactaatatatatcagaaatttttataaacaaagt taaaaagcaaacacaaaaaatttgtagcacttatgacaaatatatgtatatatatgaatacaaaaagagcctttacaaaa 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cccttaagactctctgttacttagctcaaactacccttttcaacaacactgccctaaccaggatgagttttttgcccccc tggagtacattcagcctttccttatcaaaccttcctttaaataagtatcttctccaggaccacttcactttcttccccaa tttagcattttctatatctccaggcctacctctataaagcctgtcctaaccactcaaaccctagctttttctctgaactg ctagaaatatttttctctcattggccatttaggtaaaaaggtttttactgtttattacctactcaataaaaattttcttt ttttgagacaaggtcttactctgtcgcctagaatggggggaagtggtgtgatcacaactcactgcagcttctacctccca gc caacagtcctcccacctcagcctagtgagtagctgtgactacaggcatgtgccaccataccccactacttttcattt tttattttttgtgagatggaatctcactatgttacccaggctggtctgctgatctcaattgatcctcccactgtggcctc ccaaaatgctgggattacaggcatgagccacaatatctggccccagtaagcttttaaggccattaacatgaggaacagtg ttctttacactattttatcagctagggctttgcatggagtaggagtttagtaaatgcggttgatgggttaatcaatgtgt gaaaatattcagagccaccaaaaacagatattatgtctattctcatcaacaatcaaaattgagtaaacagccattttcta atacaggaaaccacaaaacattgaatggtgacattaaaaaattcccccagcaggagccaaccaattttttcatcctgatc caagttagcaaactgcaaaagataggaagcactaatgagtggaaatttgagtagaagcatttcttatgaaggctgtcttg actggatcacatttttattgctgttggaggtgccaaatgtgtgtgtttatgctaatcctccacctcaggcaacacacagt caaggatcctaccaagtgttaccgtcaagtgtctgttggcagctcaaggccccagcgttgttcccttgcactagggaaaa gacatattccaggtacaagtactcccactttgatgctacagaggagttgctgaactttgtgtcattaatctctcttcgtt agatcccaaccctgtttaaatcccactatctgcctactctgggtcttcaccaatttactagatcatagttggagaaaatc tacaaagccttgctccctttagatttaaacaggtctccgtttaaatttagaattgctaacttcaagcgggcccttatgcg acagtatgcctgtcagtcatactacatttcctcaattccattcatgtgactgctccatacccttccctctctcttcatac tactattatctcttcccccctccctcatttttaactgatgatcttgtttcctatttctctgagaaaatagaagccatcaa aagagagtttccacaaactcctactgccttatctagccctgtaccatatactttgcatttcctctcattaccatggatgt actgcctatctgtgcttctatctaaggctaacccttccacttcagttttgaatattatcagctcttaccaactcaaggcc attgctctagcaattctctcattctctctcattttcttccatcaagttttccttttcttcaattaacagagtagctccta aagggaaaaaaaagtcttctttttcaatgctcatcatcactggccatcagagaaatgcaaatcaaaaccacaatgagata tcatctcacaccagttagaatggcaatcattaaaaagtcaggaaacaacaggtgctggagaggatgtggagaaataggaa 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agtggcatgatctcggctcactccaacctccgcctcacgggttcaagtgatccccctgccttagcctcctgaatagctgg gattatacacatgcaccaccacacctggctaattgctttgtttttgtttgtgtgtgtgtgtgtttttttttttttttgga cagagtctcactctgttgcccaggctagactgcagtggcatgatctcagctcactgcaacctccacctcctgggttcaag cgattctcctgcctcagcctcccgagtagctgggactacaggcatgcaccaccatgccaggctaatttttttgtattttc agtagagaccaggtttcaccatgttggtcaggctggtcttgaactcctgacctcaaatgatctgcgcacctggacctccc aaagtgctgggattacagacttgagctactgcgccgggctattttgtgtttttagtaaagacggggtttcaccatgttgt ccaggctggtctcaaactcctgacctcaagtgatccgctcgcctcaggccctcaaagtgctgggattacaggagtgagcc accatgcctggccataaaactgccctttgttaatatgactgttggcctgcacattgtcaaatccagtggcattcatctta ctcggccaacctacggcatttgacactgtctgtctttccttctgttcctctatctgtttccagtatactggcctggcttt ctttttacctcttttatatgctcttccagtctcaggctcctttggggatttgaaggtatgttgcattttgctattcaatg aataatgacaagtaatgatcacttaagacattaagtggtcagttcctttactaggataaaaataattttcttcccaacat ggggcatattccatttccagtctgactgttctgtgtaatctttgtattccttggcagccccttttatatcagttcatcta ctgtgcaggaaattggacaaacatttgcactggtataaccaaatacagttgaacttttggcttgactcttagctgaactc accaaaaataatttctgtaagagactgagacgtctacgagtaggtttttcagaattagtaaacataaatcaaggatacac aggtagatttgaatttcagataaacaacaaatacttttttagtatgtctactgaaatatttgtatcttatctggcaattc tacctggtacagaactaatccattctcttgaaagatcttgactctgtaataagttctttggtgatggaagggaggtattt ctgtaattagagtcactgtcttcctcccagttttttatcctggcccagatctgcaatgaacacacgacagaatccagggg ggatgaagatgggtgctttgcaggaaaaaaaaattaaaaacatctgaaaaagcttttgtactaaaagaatgtgatctaaa aaagaaagcaggagaactttctgtctgcactttacatcagaacaaccttggcgtctagaagctgtgccctgtgggaagtg gtggtgcttggtaagagatgccaggaccagtggtacccactgggagcactgccaatacccagcaaggagcatgggtgcac agtaaggcattgcactgtgattcagcataaaataacaataagggaacgtcacggagaaaaggccagacttcctttgttta gaatgtgggaaatgtcttctgaaaaatggtagtaaaaaagcatgcttggatggtccactccaggcaaaactgactaa cg ggggtcagggatacaacccctgcatcatatgtttgtttctgttgggctgacatgaggttcactgtgaccactgtggttta accccatagtctcctggaaatacagccaggtcaagagagctccacataaaacataatcaaaaaaataaactcaagtttcc actgatcagcttttcacaactcttatcctttcactaactttggagcaagatttgagaattggatggctatttgagggcta tttctgcgctttagttcaatgttttgttctttctttattagagaactatggttttttattatatttacactttaagttct agggtacatgtgcacaacgtgcagatttgttacacaggtataaatgtgccatgttggtttgctgcacccatcaactcgtc atttacattaggtatttctcctaatgctatccctcccccagtcccccaccccccgacaggccctggtgtgtgatgttccc cttcctgtgtccaagtgttctgtttatgtgatagattacgtttattgatttgtgtatgttgaaccagccttgcatcacag tcacttgcttacaagaaacaaacacttcacagatggatcattatgtgtgataagtgaaatccaaggatttatgctcagag gtgggcttaacaggtaggaagagcagtattttccttcaaccatgagtgtatgcaggtttttcttttcttttttgagatgg agtctcactcttttacccaggctggcgcgcagtggtgcgatcttggctcactgtaacctctgccacctgggttcaagcaa ttctcctgcctcagcctcccaagtggctgggattacaggcacctgccactgtctccggctaatttttgtctttttagtag agatggggtttcaccatcttggccagccttgtcttgaactcctgacctcatgaatcatccttctcagcctcccaaagtgc tgggattacaggcatgagccactgcgcccagcccacaggtttttcaaagactaaacttaaaaaaaaaaaaaaaatttccc aatgaaatataaaactaaagtgctaaactgtgatagactgttttacaagaatgccagttttcacaagtgtctatagaaca tgtaatttagataggtaagatgaaattttgataatatttgatggcaaatttaaacaggtatacaacaaaaataaaattct aagcccctcaaccaactgaatggactccttctctcagccaaaggaataccaaagtaaacctgaaaaactagttttggcca ggattgggggtaggtgggggaagcccaacatgactcattattctctcctccctttggaattcaggcacaactgaatgtca gcattgacactaaaacacagatcttaagactgacaagccagactctttgtagcagagagccaggccctggaagaaatcaa gttattttatcccaaaaaatatttctttgatatattttcaaatggccctgcaaagctgtctcttgtggggaaaattgaca tgctgtacagaatttccttctctttccaagtttttactgatccaggagagatttaactaagaggctagcatgtttttttt tttttttttttgaggcggagtcttgctctgttgcccaggctggagtgcagtggcgtgatctcagctcactgcaaccttcg cctcccgggttcaagcgattctcctgcctcagcttcccgagtagctgggattacagatccatgccactatgcccagctaa tttttgtattttttgtagagacagggtttcaccatgttggccaggctagtattgaactcctgacctcgtgatccgcccac ctcggcctcccaaagtgctggcattacaggcgtgagccaccgtgcccagcacaagacatttaccgtctattctctctgaa gctactatctagaggcttcatcaacataataagacccttggtctccacaactccttatcttatcctattagtttctactg attccaggtctttagataataacaactctttcaaccaattgccaatcagaaagtctttgaatccacctatgacttaaaag ccccactccttcaagttatcccgcctttctggactgaaccaatgtacaccttatatgtgttgatggatatctgcctgtaa cttccattcccctaaaatgtataacatcaagctgtaacccaaccaccttgggcacatgttttcaggaactcatgagactg tgttgcagaccttggtcactcatatttggctcacagtaaacttctttaaatattgtatagagtttggcttttttcattga cacaggaaaaataaagaattggaaggtctttcatcagtcactgagccagcttcatatctgactgaggtcatacagttcag tgatttgtagctttgctacttagattgctatccattatctagaagcatcaggatcacgtgggacctattggaaatgcaga ctttcctcctagaacccaggaccttggaatattcttggcacatagtaggtgctcaatacatattgaactcctaggtgcaa ttcattaattcatgaattaatgaattaacacgctctcaaagtttagtgctttttcacagactagtctttctgcctcttaa gcactcagctcaccacgcttccagtctcactcccctattagtctgattaaaatctgcttacatgtgagtctgagatcaag tgttatctcttctgagaagtcttccctcactggcccaaaggaatttctcctctattttagcactgtcccagttgacttgt cattattctagtctttttcatattagttgtttttcatatatatgttattaaggaaactagtcatttcccctaatagaaca aaattgctggcctttggggttggcaatggaggggaggctcttcttgaaaagggggaagagtgttctcctaatatttttct tacgagatttatgttgctcatctttagcctttagtcccccattgcctgcctacagttggcagagaccatctgttctctca ctgtcaggaactgtctcaattcttgaagttcagagtcaaaaaagaagcaagttttcctagctctttgatcaactttcaaa gttttacttccatttgaaaatttactaagtcaccaggagatggtttatactgagaaatatccactcatactcttcctctt caactttcttccatatacaccctattacagggatatagtcttactctatagctcaaaaggatgaccctatcagaaacctg cacagtatgtaaaacattctcaccagaggttcacttgtgtatttccaccctagaatggaagctctacaaaagcacagaat gtatcattttaactttagattctattttcacacccagtgcttgacacatgatttgaagttaatatttatttatcaagtga ttgttttaaaatcatgactcactcaacaaagttataagaataagaatagtgttacagaattggtatacacaagctgacca taatcaacacacctattatcatttttttgcgacaggttctcgctgtctcaccctggctggagtggagtggcatgaccacg gttcactgcaggtttgaacttccaggctcaagcaatcctcccacctcagcctcccacatagctgagcccacaggtgtgtg ccaccatgtccagctaactttttaattctttgtagagacagggtcaccctatgttgcccaagctggtcttgaactccttg gctagagagatcctccctccaaggtcccccaaaatgctgggatctcaggcaagagccaccatgcctggccataatcaata cacttttaagaatgctagaatgttatatcagatgcatacttcagcactatctcaagcaaactggggtgtgggttattcta catataaagttcagcagtgttgttccacagtcccaaactccaactgaggtcaaatgtagggtgcagcaaggtcactgggg ctgtcatcaagggcctctccttgcactcttgccaaccctgtttcttgattgtctctaccaccatgagtcaccagcaatct cccacagtcacttgtttaaaagttcacaagtattgtgtgaattgcaggcaaccccttgactccctgattgcctggtcttc ttccttgggctctaccattttttttccccagcactctttctgctgctctaaattttaattcatgcaattccatatgtgtt tctctatcattcttcatctctttcctctcccttccatccaattttgtttgtctgtttgcttgcttgcttgctttaataca tttctctttttctgagaaggcttgagtccaaaactctcagttacctgttgttctgtttcccgttagttaatctccgaacc ttcataaattaaatctgacaaagtcccctgactaacaaaggaaatgcacaagtcacagtaaaaggggcacacacagaaca caaatagacccagggtcttttctgttcatcactcagctttttataggagatccaggagaaatgaagtggaaagggaagtg tgttgagttactatacaacacaagagtaaactttcttataagtggtaatttttttttacaggaataattgaaaatggaaa ttaccttctctactcatagtaagtactcagtgcgttcttgatgggatgagaatgtgtttgagctttagtgtaaggcagaa ttctgtttagtctgccagtattggagaaaaataaaacacaaagggactgacatgtaggaagtggcacctgggaggg ctc aattcttcctattacaaaaatgccccagagaaataaaaagcttgtgtacatgttgagatgggagagttctctggcccccc tcgcaggatgtgtgacagtggggtggctctctgctgcgccaccatgagctcaaacccctcataggagggggagcacacag gcaggaaggtgcaggagctgggcgagctctttgggctctggccccgtggtactgtctagaggtgggtgcctgcaactcct gaaagcccaagtgggcatgtgttacagtgcactctttcagctttgctgtctgcagcttaagcgttaaccagctcagtttc ttcttggtacccaggtccttgtctggcatccaggaagaatcaggttacacatggacttgaaggatgaatgtgggagtttt atggagtggtggaggtggctctcagtgggatggatggggagctggaagggggatggagtgggaagatgatattctcctgg agtttggctgtccagcagccgatctcctctccagtcgtccccagcctctcgacgttcagatgctcctcttctctccttct ctgccatgctgttctgccgttcatctgcctgtctctctctggagcctggaatttggggtttatatggtacacaataaggg gcatggcaggccaaaagggaactttttaggtgcaaaaaacaggaatgcctcttctcacttagggctatagattttcaggc ttgaaggtggggcctttaccagcgaacctgtatttccctgtctcctgtgcatatcaatgtaatcaaatactgggctgatc caggatgtttctttagaccaattatgggtaaaataatttacattcaggtttttatatttgcttttgtcatttctttttaa gcaatcatgtaaaatatctatacgacagtaatagatgatagcgaacctaattaaaattaccagaaacttaagaatctcta atgatttcaactgtaactaaggttatttctctttatgttgaacaatgttgggagataagacacaagagtttctgaagtat ttcagaaacacaaagagggaggttatataaataatatttttttcctactttgggaaaatgaaagctagtcacaaagttaa acgagtggttattttaatatttaaaatacaggcttggatgtatttcctgttaaagaaaataaaatgcagaatattcaaaa cgtctgaccacccttctaagaaaatgcatctctgaggtatttttccttagaagttattgtaaaaatcctggagaagcttg aacacagcaaagcaaacaggatgcagagtttaatctgtggaaagcttagggaagaaaagcaaatcattaaaaataggtct tcctctgaagatttttaaaacgcaaagagggtggaatagcaatgataataaaaaagctggcatagagagtggcacaattt gctgtgccactgagctgactggatgtgttctgaatttctaggcattagtgtacctttccacacgcattctccctttaaaa aaaatgcccacacactgaatacttttttcatgcaatttaaaataagcgcaccatctagtttacagaaattcactagaagt tatttatcctaaaatagcagagatctagaagaattttgagctctaggacattttagacacacagaaagaagaatctggac aagtcttgaccagacatgacagaatagaaatttcttttcctatttatctctttgaataaaattttcaggatcttacagtg gacaagtttgttatctacacattgtgaagcacattgatttctcctctgtagccttaggaagatctgagaggtgactgagc tgattgaatgatccgtgaccgctctactgggaccagtagtagaactttactggtggagacctgctggaggtttgagagca gactttgaaaattactagagctacacagatactgtgtggctaactggattatgtttagaggctttcagaactatgctgct gctgctgcagtgtagccaggacgcacagagaacatctaaggctcttgaatggggcgatagggacagatttcagcagccat ctgacttcagtgctcattttgatgctttccctgcagggtgcagtgtgcagtgtgcagtgtgcagtggtgggaggctcaca caggaatacttgcttctgtagccctaatttccggttcaaactctgcattcaccttgacagattctttccttggccaaaat ttagttaggcttctgggctttctcttatgcccacctgcagactttttggtaaaatccagttttagtaaagagctctgcta agtcagtttagcaagaatccccacctcaaaagtcactatctccctccctggtagtgtctggcttgtcttcagcgagaatt ctattaggttctgttagattagaatcctccttacccttgatgcttcctcttagtattttt catccactgactccttgac ccaccttgctcctcggctataaattcccacttgcccatactctgcagttaagactattttctccccactactgcaaaatc ccattgccatggtccctatactatctcaatggtaatgaataaagtctgccttaccatgctttaacaagtaacattgaacc atttttttctttaacaatctgctgcacaatgagattactaaaactttattccattttgccatgctggatgtcctcaatgg aatggctcttgtgagcaccaaatcattgtgagaaggaaaacccatctcttacagccccctgtaacgtgatgtatgttaca tgtgatgtatgttacatagttttttttcatgttgatcactttttgcccattttcctatatcttatcagttggaagactgt ggaagtttgtagtactaagccacaagatgactaagaagagttgaaagggcaagtggggctaaaaacagattttgtttgac ttaccccaccattccccctatcatggggctgaatctgcctggaggaaggagcatctttatctttgtactgtgaaccacac agtctagcagcagcacagccaaggcacttggggtttcatgagactaagtacatgcaattctattgtaaaggcttaaaata tatacaactgacccttgaacaacatgaatttgaattgcatggtcagttatacgcagattttcttccacctctgccacccc tgagacagtaagatcaatcaatcctcttcctcctactcctcagtctactcaaagatacttgaagtctacttgaagatgac aagcacaaagacatttatgatgatccacttccacttagtgaatagtaaatatgttttctcttcctcctaattttttaaca ctttcttctctctagcttaatttattgttaagaatacaatctataatacatatgacatacaaaatatgtcttagttgact gtttatgttatctgtaaggcttcaggtcaagagtatgctattagtggttaagttttcgaggagtcaaaaggtgtatgtgg actttcaactgcaggggggtgggcacccctgcccccatgttgttcaagggtcaactttactgccaaaggcaagcctttac atccactttttccatcccatcagtaaatggaaaaagatagctacagtatccctgcgtcaaatctttttttttgcagatca caaattggccactcaccttgctctgtgaggggtaaaatgccccactttctttagtaatatttaagttagataatatttaa gttataaagttgttctttgtaatcgttaattgtaatttttacatagtttctttcaaacagaaatagcatttttgttagat aacctcccgtatagatgatgaaactccttttaagggctatctgaattttaattccttgaaaaggcagaaattggatagct agtagtcataaatgtactgtggcttcccccaaccatctgggctatatagaagctgcatccttggactgcagtagaggagt cttacaaagcacagagcaacttctctcctgggttgcgctagttatgatggcaattttaaatgtgtacttttacccaaaga aaatccttattatcaacaatcacaatgccatcataaccatggtataaaaaattcaaaatgtcccagctgaagtggaggca aagactcaagttcatggagtcagagtttccttgctattcctctttttcaaatgaccatttagtaagcacctgaagaaaat actatggacggcattgaaaagtgaagataggtttaatcttctcgaaaatctaattctccagatgaaacgctgacacttat ccaccccacagaccctatagcagatgtgtcactggccatcacatttgacacagagaagtcataactcagtcagcacagag acatttccatgagtttctgaaccatggacagaacgtcgtctgtgggacatgaaaactggaacttagaggacaggcacatc tgagaaatgggcagtttaaaggcagaacatagcacatatgtgactgggttttagaagcaaatttacaagacgcactcttc ttcatcctaaataatctgcaaccaaagcttccaaaaaagacaatttaggaatgcagaggtgaggagtagggaggggaatg ggatgagagagagtggagattaatggtgggcagagcgaggtttagaacttagtggtttcttcaggttctgaactgaaatt tgtatactgtaaaggcacaaacaccatttttaacaaaagtgagcaggacttcctatctggttcagaaaataggtgaataa atagtacgaattattaaaaataataatttccacttatacataggaaacttgataggaaccatgataaatgcttaactctt aatcttcaaggaactctgctagggatataatattataaatcttgttttgcagatggagaaattgaattttaacccaagtt atcataacccttaaatgattaaatgatactgttacatgagaaagctgcgtatctgtttcctggatttgtagccataattt gtgtctcaagtcccttttgctgccagctatcttgggtaggtgtgttccctttgggctgtttgatacccccacatttatct tttttttttctctttttttgttgagagagtctttccctgttgcctaggctggagggcaatggcgcgatctcggctcactg caacctccgcctcctgggttcaagtgcttctcacgattctcttgtcccagcctctctaatagctcggattactggcatgc accaccacgcccacctaattttgtatttttagtagacaaggggtttctccatgttggtcagggtggtctcaaactcctga cctcaggtgatctgcctgccttggcctcccaaagtgctgggattacaggtgtgagccaccatgcctggccccaaatttat ctttaatgccccaaattatctagttcccatgactgggcttctgctttgatcctttctgcacttgctggaccctctccctg ggaaatgagattgtgtcctgagcccctagttagaggctatgtctctgctgttcctgaatgggcctcctggatgagacctc attaaaagtctaattctcttggagaattgagagatacctatttgtctcaaaatcattgaaaccaattaatgtattatgag cctctatccagtgatttgtacctcaattccccaatccagctgtcaaggccaatttgttctaccttacctagtaggtaagt ctggaattgtagctgtggcattttcagtaatggtactctaggttagcagtccccaacctttttggcaccagggaccagtt ttgtggaagacaatttttccatgaagggctgggcaggggagtggtttcaggatgaaactgttccacctcagatcatcagg cattagattctcacaaggagtgcgcaagctagatccctcacacatgcagttcacaatagggtgtgcactcccatgagaat ctaacaccgctgctgatctgacaggagacagagctcaggcagtaatactcatttgcctaccgctcacctcctgccgtgca gctcagttcctaacaggccacggaccagtactggtccacggcgcaggcatcagggacccctgttgctaggtataagcatc tggctgctgcatgtcttctgtgtagctacatctgtatgtgtatctgatgagatataaattatttgattataaattacttt cttcatattagagttgtgaatgagtatcacatataattatacataaactaggaatatgctttttaataatgtatataagt aagtttccttaactatgactttcatcttagcgtagtaagagggtgctaagaaatatttgtgatgaaaataggcattggta gagttgagaccactgggtgatgaaagagtgtaaagattttaaagcc.ttcagatgctggttcaaggtgagaaatgtgattg ggagcaaatcaattaacttcttgaagtcttatagggcagttatgaatacttaatgttaacatatgtaaagctcttctgcc ctgtatacagtaaatgctagttagctattatgatcactactaaaatggggatgacataaacctcataaggttttaagtat tatgcaagatactatacaaagtccagtaaatatcacattcaattgaatccatgatgtccgattattttagctacttccaa gagagaaaaaaatgctgtcagttttactgttcttatagagagcaaggcagatcccaattcccaatgtggtaacgtgaaaa tttttgcatttgaatcaacaaaacactttctcctttctttcctactatttaacaactggtaagtctatactcccccaaat ctggaattctcctttcttattctttttcctcctaccaagaccgcaggatcttttacttggctataaggggtaaacctcaa gtagtacaagttctctgtattacttttat.actctgtcacagattccctttgtttcctcatctccatgtgaatttagttaa attctcagcattctgatccttactatacaaggtaaatgaatataaaaacaaaacgaaacaaaaacctcttcctatttaca taaggccccaacctaatatttagtgatatatattaatgtgaacaaggaactaacgaagactgggaagaaattcacagact tgagagaagaaatggcaggatttcctgggaacaatttcatgtaacgtcaaaggtggtaaaaggtcaaatagaatgaagat ggagaataccggattttcttacaaaatgatttcccaggagatctcatcaaatgcacgaggataccttctcagtttcacct agtgagtaaaagactggtaacatagctcacttacaatttggataaacaaaactaaacaaacaacatcaaaatttcagaaa aaataatagcaaaacagaaatcaaacactcaaatttttggtccttctgtttatttcattttggatactcagtgaatgtta attaaccaggaaacttaaaagttatttcaattatgaacctcttcaatccttcatcaattattttgagtattctggtctta aaaacatctctttcttctacaaacttctgaaagagatgaacacctccacctacaccaaaataatgtgctttgctggccaa aagtacacgtccatttttacttaacagtctaaggaaagtctggtgcaaattactataataatctgggttgtaaatggttt ctgaggtgagaatgagatcatattttacaaaaagtttttcactacttagtacaagcttacaaaactcagaccactcacca gaaaaaaatcggcatttat tagttgtgttacttttggtttcctgcatcttttcacatctggctcatttacatcattttc ttcatcttccaaagtggagttagctactacattaggtaaggttacttcatcaatcaccatactgttataatcttgaaagt gaatttctttggaccctcccttgaatgcagttatacctagtaaacctgatccacaaccaagatccaagacttttttccca gcaaatttcactttggcctttgtgaaataagccaggaggtcaaaggtacattcccagatttttaagcctccctcataaac acctgtaatcagatcagagtgagaagaaaagctttttgaaactatgttttctccagggaagttctctttcaacaagatgg ttttcactactgataacttaacatgctggaaacctggtaatgtttctatgactttattttctaacatcttctttaaatct ttaggcatagcatgctctttggcagctctcaaggagggctgttttccatgtggctccaagttccttgaactgctggctgc actgagtggactgtctgtgtcttgagagggagctgcattttccattgacttatgttcccacaagtgatcctgaggcaagt caaattgttctgcagaacattttctgtccctctcttctcctttttgactttctgagactgacagctcttttgaggaatcc agggtcaaagctccatctctaatgggtgttaattcattttccagatggtcttctatagtgaaattaaactgaaaggtcat cctcttattaaatgcacacaatctttaaattcagattcttcaacttctggatagaatttgatgatacacacaaatctgcc tcaattattcaattagttttgttgggcccaatttctctttagcagcttatacatggtaacaaatatttagagatatttcc aaatgactttttagacgtctttggtcctctttccaagcagctctggaaagaaaaaaaaaaaaaaaagaaagaaaatgatg attaaagcaaaatggcacatttcactaaagtgtaatattaaacagccacccccacccctccctgtcccaccatacagctg ctttttcttaaaaagttgtggggaagagagagagataagagatttggacactcatacacaccttaagggttccaaagtgg gagaagaaaatcaactataaaaacaaacagaagaacaacagcaaccaccaccactaccacctggacaaacataaagtcca agatattcagacaggacagcctagctacttgctgtctttcagctgtcttgatttgtgtccaaccatattcaccccctaag cttccagaataacttcacttctgtcttttacagaagaggtgcagtattttattttggtaagtcagcgtccctttaaaaac atgcataggtatggcctggtgtgtgtaaattcatccaagacttcactccaaacatttagtcgagaacagcagccctaagt gtatagaagtgggggtaatttggcaataattagtaaagactaattcggtggcagagcaaacgcaaactagggcactgcag tagtttggagagacctgtagaaataagaagcaactttattgagaatcttctatctactgcgctagacactataccatctg cctcaattttcacagttctggcaagtgggatctttgttccctttatacaagatttacaatttgggggagaggcgggtcac ccagtcccgcggctaggaacgcgcctctttcctctcccatcacgctgcaaggcttggagtcacttccggctgcagg ccc ggaacaaatccgaccccagaagtggggacttctggccctcacctccccatttgaatgtaatgtttacagtgatccagacc tggggatgcttgcttcccgacgtgtcctgggatcgcgcttctgaaaaagctcacctcacaacgcctcctccggacctaaa tcgcgcaccagtgagtcgagtcctccaggggctagagaagcccgactttctttccggccttgagggacccgggctcacca agaaaccagccgccctcctctctatggttttggagccggcggagagcgcgcaagggttggcgggactgcgagtttccggt ctgggctttggcgggtctggtttgaagctctcctgtttgacgaaagtatgtctcaggaaggtgcggtcccagctagcgcg gttcccctggaagaattaagtagctggccagaggagctatgccgccgggaactgccgtccgtcctgccccgactcctcat atccttccttggttgtcacttctacctagagaagggtgtgggcgggtcgcgaacctttctcttctgtcccttcagaccca ccgccaggctgggttatattaccgcggcctgaaccccctcttttctttgtcagtgagtgggatgaaaagtgagggactgg aggggaagcgacaaccgtggtagatttaagtaaggctttggccctggaaagcctcgcggacgtgttctgacccaaggttt tagcagtggatgtggcgttttcttccattccttctttcagtttttctgtactcgttgcttgcaattaagtgtaaatactt ttgctagtggataatgggggaggcaaggactgagacctgcggtatgacgatagctctggctcttaatagtttgaggtaaa gcgagatactctgagcttttgtctcccgtaaaaagggtggtgaatatgaataagggctttcttagcgttataagaattaa agggcatagttctgtggtgtgaaatctttaaaagatgttcagtaaataaaaatgattttcctccttcccctctcagacct ctttttcttctttctttctttttttttgacaagttctcactcctctcacccaggctggagtctttctgaaagagttcttc cgcttgttgttggctttcaactgttggatttgaggcgcttagcgccttcttcgtccgggtgcagcacattcttgattggt ctcatgcctttgtggttgtaaatgtgcctggaatcctagcctttcatggtaaaccatatgtatatgtatctttttcacaa catttgagcccagctttatacaattacactcaaaagaaaaaaagtaaccttcacttgagagaatctcaatactgcacaaa tattgtgcagctaaagccctatgtaatcacatagaagtcattcacctaggcattagcaaaatctcagaaggtgccaaagc ccccttttttagtttttgtgtaggtacagaactgccgtcttcaaggagtttcaacttgaaaacaaatagccaccctcaaa acattcaaaaacacttaaactgcgtgcataatgtgtgtgagacatggtgttaggctttgggagaacagagacacggaacg tgattcctcttcttccccacaagcttatagagagacttcattaagttgaaagtcaacattcccacctagctttgcacttc aaacgacatattcaaaaaagcccaaacttcctctagttttcttcatctgagtaaatggtttcacaaactgaaaccttgaa tcctctctgtctcacacacccgatcagtaagttctattgtttctgattccaaactatgtcttgaatcaatccgtttatct ccatcctcattgctaccactctgattccaaacccttatcacctctcacttggagtattaatagtttccttgtttctactc ataattcattattccaaaaaagttaagaggggaaaaacatagatctcgtcatttccctttttaaaccactttaccttcaa ggttccaggtgatctaagccttgcccttctctcatacctagttaattaactacactctgttcatgaatacattaggctca cctacctcaagatctttttgctcagcctgatttgttctctcagccttttgcatatttcatgtttatgtcttggcccaaat gtcacttccttagaggggctttttcagagccttcaatcttaggcagttcccccaaacgcagtcttacacttgtatcacat tggcctgttcagttttctaaaaagcacattaccattaaaagaaatgctcttgtttgctttgtatattttccacttctaca cattatgttgcaaagttcataaaggcaggatgttgattttcttcacagcgttaccctcagcacctagaacagtgcctgac acatagtaagcattcattaaagggctaaaaatatttcatgttttaaaaatacttgggagtctaattagacaatacttttt ttcagcttaatggtagtattttagcttcactattttaacaaatgaaaaatttgcaataaatctacaatgccattaccccc caaaatctttttcatgttttgcattttacgtattattttccaggccttacctgcatgtctgcataatcataactgactaa ttttggaacagctggtaattatttgagctttactgaaattttttcatgaggccaattctaccctactgaactcaaatttg agttaatgatgacctcattttgattgctgctgtaaaaaataagatttcggaagaggaatgaattcttgtattactgtggt aggactatgggtttttttttgtttgtttgtttgttttgagacggagtctcaccctgtcacccaggctggagtgcagtggt gcgatctcagctcacagcagccaggttcaagtgattctccttcctcagcctcccgagtagctgagattacaggcacgtgc caccatgcccggctaattttttgtatctttagtagagatggtttcaccatgttggccaggctggtctcgaactcctgacc tcgtgatccgcctgcctcagcctcccaaagtgctgggactacaggcgtgagccaccgtgcccggccgggttattcatttt tcttattaacattctttgatgattcttatggtgttgttacagtaaaacatttctaacaattattctaacaattattcttg atggtgtatatgaagaatttattgtcgtgtatttgtaagctgctatgtgcagaagaatttcagtcaaataaagttggtaa gataggtatgtaagtaatatgaaaaaagatagaaggtgatgagtgacttaggtataaattaagtacaatagaaatgttga ggaaagaaaaatttcttgtaatagaaatcggaagtacaaactgggcatggtggtgtgcatctctaatcccagctccttga gaggctggtatgggaggatcactttagcccaggagcttgaggctgcagtgaggtgtgatcatgtcaccgcactccatcct gggtgacagcaagaccgtctctctttttttttttttttgagacggagtctcgcctatgctggagtgcaatggcgcgatct tggctcactgcaacctctgcctcccagtttcaagtgattctcctgcctcagcctcctgagcagctgggattacaggtgtg cgccaccatgcccagctaattattttgtattttaagtagagacgggttctcaccatactggccaggctggtcttcaactc ctgacctcttgttcgcccatctaggtctcccaaagtgctgggattacaggtgtgagccaccccacttggccccgagcgag accctctctctaaaaaaaaataaataaataaatcataaacctgtggattattgtagcattgtttctcatctgtcaaaaat atttcatgactatgcatagtttgaaaaggcaagtttgtccctgggcaattttcaaaatatttctttaatgtgttttcaca atactgtttacctaataaatcttaagtttttaaaagcaaaattaagccagtaatttgagtccaattccaatctcttatga gtcattgcttaaatttcaaaagggttttattttttttttaggtttgttctgagtaatgaataccctattactatgatact agtatcttccttaattatcctactcattgtctcaacattctgacagttggattgagcatattcgtaagtaaaattgtttt aactgtatgatgtactttgatgttaaggtccgagtccccacatacctcggtagatgtgttcttacagttttgtattccct tgaaatgtaactgttctctatgttacagcctttataaccttcagttacttgaaatgaacaaattcattcaaattccagca cttaaaagttttaaattacattttggataaataccaaagtgttttgttgatgatgtatgtataaacaaattgtaaatatt aaacgttagttgttacgattagacctatataaaacatgatatgcagtctactgaatagc tcagcctctaacatgttta gtgtcatttagaaaatgctttctaaattgccaaaagctgattgtctaggtgataacaaatttaccatttggaggaagttg actttctcattttcatgtcttcatcagtcttacttgatgagattcattcttctagtcagaagagagtttagactgctcag tttactcatattttgagttagcttttctatttagagttcacttggttgtggaatattcatttataatttgaatctacgtt gtgtaatgggacctaatttttttttcctttgtttttgttggagtctcgttttgtcacccaggttggagtgcagtggcgtg atctttgctcactgcaacctccaccttccaggttcaggtgattctcctgcctcagtctcccaagtagctgggattacagg catgcttcaccacgcctggctaatttttgtatttttagtagagatggggtttcaccatgttggccaggctggtctcaaaa ctcctgagctcaagtgatcctcctgccttggcctccataagtgctgggattacaggcgtgagccgctgagcctggcccca gagtttgttttgttttgttttcaagacaagatctcactctattgcccaggctggagagcagtagtgcgatcatagctcac tgcagcctgaactcctgggttcaagctattctcctgcctccatcttctaaagtgctgtgattacaggtctgagccatgat gcttggcctgtgtttttgtttgtttgttttgggggacagggtcttgctttgtcaccaaaactggagtgtagtggtgcgaa catagctagctcactgcagcctccatctcccacgctcaagcaatcctctcacctcagccttccaagtagctgagaccgca ggtgcgtgctaccatgcgtggctaattttctatttatatatttattttttggtagacatgaggtcttgtcatgtttccca ggtggtctttaactcctgggctcagacagtcctcccgcctcagccacccaaagtgttgggattacaggcgtgagccacca tgcgtggcataattttttttaagtaaattatttttttatcttgagtatagaagtgattcatgttcattgtggaaaatatg aaacatatagaaaaacagaaaagattacaaaacatctaatctgaaatggttaagattttgatgagaacagtctcatctca tttccgtatattcctgccagcctatccatcattcttcgtacatgtttatctacattaaaattggtgttatattttggaaa ctttttgtttaactacattgtgaacatttttcatgttttaaaatgtcattttaatgatggcagatcctattcaatagatg tacacacacctatttaactggtccacaattgttggatatgtaggtcgtttcctttctctctttttttttttttttggcta ctacttaatagtttctctgtatagaatgtggtattttgaaagtgtatcaagctttagattggtagtattcttgcatttaa taaagggcagtggcctttgttgactgacatgacaatatttttataaaatttgttatttgctttacagaaattttgaaaat tattgtagaaatgtttttacctcatatgaaccacctgacattggaacagactttcttttcacaagtgttaccaaaggtat aatactattacctgaaaatacatgttataaggaatctagcctcagtcttagatgatttattattaattatggctctcttt ttctaatat tcaaatatattcaaaataaaaataaggagtaagtagatctcatgtgagactataatggtgttagtgtgat cattaggcagttaaaaactgttacaggctgggcacggtggctcatgcctgtaatcccagctctctgagaggctgaggtgg gcagatcatctgaggtcaggagttcgagaccacccatggtcaacatgatgaaacctcgtctctactaaaagtacaaaaaa ttagctggacatggtggcaggtgcctgtaatcccagctacttgggagactgagacaggagaattgcttgagcctgggagg cggaggttgcattgagtcaagatcgtgccattgcactccagcctgggcaataagagcgatgctccgtctcaaaaaaaaaa aaaaaaaaaaaagaacttatattttcagattgtgtggttcctttactaactgaatttaaattatttgtagtcaattttaa atgctcttgtattttaaagccactgtactccagcctgggtgacagagtgaaacccttaattcaaaaaaaaaaaaaaaaaa aagaaaagctggaatattggcaaaatcaagtaactaagagaaaacattaaattcacagaatacattattacattttagat atatatggtatatgttttctctgaaaagcacaagcataccttttttgttttaaatggagggaactaaagatactttggtg ccaaaatgaaacattatttgtaattaatctcttattgaaatgggtttctaactttagctttgaatcgtaatctttcaaat ttcttgtactcatagtcacttgatgattctctatctgaaatatttcttagaatttgttcttgaccaccagaaaaagattc aactgttacatagatgaaaatggatgttgagtgttaacaggcctatgggaaacagtattttctttagctacattgtattg ttgactgtgttgctattcttataatgtttaggtcatttaaattgttagaaagatccaagtattaagatctagggtggcta acttttcacagacaaaaagcttgtttgtaaggtcatttactatacccttaattcaggaaggttagcttgaattgggtcaa aaggaaactggttagaaaataagtgagtagtgaataggcgattcagtgcaaattccttccagaaaatacccttgtaaatg actgtatgaatgtggattcttcaagacagtcaaatttattgtgcgaaagtaatacttttattttttgcatctctaaaaca tgaactttgagtgattttttaaaaaaattgatgctattaaatagattcaaaccatagaaatggaaaataaatttctgttt ggggcttttggggggattatgttgtaaaaataccttttctctgtattttgtgcttaattaggtacaattgttaagctaga tgatagcctgtggatgttactagtgcaaaatcaaattatcgtattgtgttttctctgtaaagttttgtcttgtcttttct agtgatttctcttattcctgtttattacttgatttgtttttacagactgtgaaattattcgatgacatgatgtatgaatt aaccagtcaagccagaggactgtcaagccaaaatttggaaatccagaccactctaaggaatattttacaagtaagtcaaa tgtattagaaagcaggagagagagggagcttaaagaatgtcaaaatttttatactgatactgattagctatgtattctta tgtaatggcctaatgttggaattaaatttatagaattaaagacgtgaatatagaaacatgaattctgaataataaactct tataagaagagaagtcatcaagctagctgaccctacctgtattttcaaggatatgtgtggaacacctgccatgtgttttg aagtttgtgttagtattctaaatggctagacagttgttccagtatttgtagttctgatagactaaagttctgtgaaaaga ggaagagactgtgttttgttcattgctgtatttgtagcacccagcatgctgactaataccttttcagtgcacaaaaaata tattctaagtgaaatttccttccttattcacagacaatggtgcagctcttaggagctctcacaggatgtgttcagcatat ctgtgccacacaggaatccatcattttggaaaatattcagagtctcccctcctcagtccttcatataattaaaagcacat ttgtgcattgtaaggtgagtaaaggtctaattatactttgaatggtatataatcaatgtgcataggggctgagtaaaata atgtttgtataagattttacattttagtctatattattgaaataaacttttccatagaataaagaacatgtaagtaaata attgttgcaaaaaaagtggttttaaggaagtcattaaaagtggctttttggggttttttagttttatcttatttcccctc tataaagaaagaagttttaagaatttgtgttgagacagacacagggatcctgaaatagttatgtcatgttgcattgacca atattcaattaccattatgattagatgtcagaacttccttttataaaggaaagttaatccttatttagtccatctctaca tgccagaggtagccttgaggcacaaaagcttgcctagaatttatgggtcacagacagttttaatattgctatttgttggg cgaatgaaaatcactagttaattaatacctctctttgctgataggatgctaaaaatgtcacgcacctggcctaatgttac ccttttttagttctgtatttgcaagatcatggaagtcagaaataatattttatacatgcttgcatctcttgaagcacact atatttaatggatgttcactaaacaatgaatgaatatgtgattcagtaaatttatgatctctaatagtatgaattaaagt aaatttggctcttgagctttgatttgttttttctctcatttttatttatccgtaatcagaatagtgaatctgtgtattct gggtgtttacacctagtttcagaccttctccaggctcttttcaaggaggcctattctcttcaaaagcagttaatggaact gctggacatggtttgcatggaccctttagtagatgacaatgatgatattttgaatatggtaataggtgagtgaagaaaac tttctgcttagtatatggtgactataaatcatgtatcaattaaaattgtctctaatgattcatgttattttcttactaat tatgcattaaaattgatttaaatcttaccaaataaatttttaatcttgaaatttggaatttgtaaaatttattttgggta ccttaacctagatttgcgtatttagttactgtaatttctccacaatgattaacttatataactttataatctctgaggtt gtccatattcagagacaataactttcacatttttttaaccataactgatattgagatgcagtttatatttccttccagaa tacatataaatacgtgcatatgtgtatgtaaatatgtctattctcatatacatattataatgaaataactcattttacat gtgatgcactttatactagtttatttttattttattttatttttttgagacagagtctcactgtgtagcccaggctggag tgcagtggcacaatctcggctcactgcaacctcgcctcccggactcaagcgattctcctgcctcagcctcatgagtagct gggattataggcgtccgccaccacacctggctaatttttgtatttttagtagagacagggtttcaccgtgttggccaggc tggtcttgaactcctgacctcaggtaatccacctgcctcagcctcccaaagtgctgggattacaggcatgagccaccgtg cccagccaatactagtttatttttaaagaattgctggtcgtaacacacttcattgattttatcactcattaatggattat gaacaagagtttgaaaaacaatataaaggcaaagtttgcattcaaaactttggtataaagagagtaagttggttttgtgc agtgtatcaggcacctgttgctctgcaacacaccacctcaaaatctatttattcactatttatttattcatgattctgtg agtctgcagtttagggtgggatgtcctgagacaactttctctgatccacctggggcactagctcacccatgtgacttcag tgacttcattcacatctggctgttggcagaggcagaagtacttgagaaagccatgtgcatcatccagcaggttcacccta tctcagatacctgatgccagtggtttcagggtttctaagagtagcaaaagtgtgagcaggtcgctgtgtgctagcacttt tcaagtttctgcttgccttaattttattattgtcccccgggccacagcaggtcatagcgtttagcccagagtcattgtag aaaagtgtggattcacaaagggcagtcattgtggccatttttataaataatctaccacagactgagtaaaagccttgcat gaataccatggatattaatttgaattcttcctttttagattttctttccttagcaatttgttttgtcattttggattaga attatatctgtagaatatttcagttataatagggtacaacttttattccactgaacatctttagttttatttaggtcatc tggtaggtataaacttcagaagttaatattcaatatttataaaaaccattaacaagtgtgacacttaaatagtttaaata attcttttgacacaactgtttccaagttgtgttacgtattttaattcaatcaaatgttgaaattgttcagtagatagttt taattataggagaaactcacccccatgacatttggatgtcttaaaagttctgttatctttctttgcagttattcattctt tattggatatctgctctgttatttccagtatggaccatgcatttcatgccaatacttggaagtttataattaagtaagtt tgtttgttattttttactttttagaaaatgttttccatattccccaatcttaattattcatgattctttagattgcattt aaaacattttgtgtgaatttaatgttcactgacactgctgtctgataatccagatattctacatgtagctctcaagccaa attggacttctttaccctgtggcctctaaaattaaaaaaaatgttcttcctagttagctagtacttcagaaataatgggc catgggccagactagaacttaaccacttttcttctgctactgttgtttaaccagctatcaagtatcctatttctaggatt agataaattgataactataattaaaactgaatataatcttttcattaggtacttttaagttgttcacacttaattccatt tgtacagtaattttaactttctgaaactgaagcattttaaagggtcaccagggatagtgcctgtagcattcatcagattc ttaggggtgagaggagatgtggttgagatgtaaaaatggttaagaatatctactttatacacatacataaaacattaaag gtcagtgtattttcaggtcttaggtacttttcttgtactaccaggacattaagttgccattcagtggttaagagtgttgc ctgggagctgtatcacatgtgcttaaatccattcttgaaatcatttactccttctgagcccttgggctatttggttaatt tctctgaacgttagtttgctcatctgaaaatggaaataataatagcaacttcttgacagggttatagtgagaattgagtt catcactgtgaaatgcttagaaatgtgcatgacacatagttaatactcaaggaattagccacatcactatcatcatcact gattatcttccactcttaccctcttccagttcattttctgcccagcagaatgatcttttaaaaagtaaatcagatcatgt tactctattgcttgaagtctatcccatttgattaagaataacaacctaatcctctgtggatgctgcctccttcaccagcc tgtctcatgctgctctccctactcttagttcctcaaacataccaaactctcctgtcccagagtcttttcgtggtttttcc atctgcctaggatgcttctctctcctattttgtgtaccttgctaactcctgcttactgtctttcagttctcagcttaaga gttatatcttcatgataacattctttgatatccttaccctaagattaagttagattgatatccttaccctaagaataagt tagattaggtctctctattgtagcaccttagactctgtcatttgacaaatcacagccctaattaattattcttaaaatta tttaacattctctctcatgctagaccacaagtttcatgcaggtaaggcggagattgtgtccatttgtttgacccctttgt ctccagggcctggtagaatgcctcatacatagtaagaattcaattaatattttacacagagaaaaaattagcaacttatt taaacaaatataactgcttcagaggtaaactgggcacatcttagttatattatgtgatatatgatgctttttgattgttt ttttaaatgttctacaaggtagatattgttagaggtcctaagttacttgatgtgttacttgtggtgattgtattcttttc tttttattcatttaggcagagccttaagcaccagtccataataaaaagccagttgaaacacaaagatataattactagct tgtgtgaagacattcttttctccttccattcttgtttacagttagctgagcagatgacacagtcagatgcacaggtaaaa tttgggctaatagcattttaaacagcaactcttattttctttggcagttagtaaatctcatttgaatgtctgggtcagtc tatttaagaggattttaatttatttcatttgggtgtttttttttgatctgtgggattatttatatcccataattactttt cacccagagcattgtattagattcctaactgctgtcattgcctctggggtctgcctggctccctctttgcttggtaactg gttggtcacagcattcttctcagaatcctttcattcttttctgcatgagaacaaaaattcttttgttcatatttgtataa gatctgatatagctgcaatcaatcttgcattttttcttcaccaacgcattgcgacctttagggatacaagtatgtttgtg catgtatatgtatgtatcagtcttttaaatttgatatagtcatacatttgtttttattttgaaaagttagagtgttgaat tggtatcccatttatgaaacattatattctaaaaatttgtagtacgattattgggaattataactcattttcctgtaaca ctgttatacatagtaccttttgctttcagactagccctcaattttatttaactatagtagtcctaaattataagattaat agtactcaggacctaacagttatatgtcatttgttttttttttttttgagatggcgtctcactctgtcacccaagctgga gtgcagtggtatgaccttggctcactgcagcctctgcctcacgggttcaagggatcgttctgccttagcctcctgagtag ctgggattataggcgcctgccaccacgcctggctaatttttttagtagagacggggtttcgccatgttggccaggctggt ctcgaactcctgacctcaggtggtccacccgccttggcctcccaaagtgctgggattacaggtgtgagccaccgcgccca gcctatatgtaataattttaatgggaccatgaattgaatatttcttccttgaatagcaatgacatagccccttctattgt acatctgcaagctgatacagggaattcctttgtacctgcgctcttccctgccagtcagctatgggggtgaaagtgtaggg gt catccaagtcctaaaactggtagcaactcctagggcagggctgatctggaaggacagaccctaggggagggtggaac tttaaaaagaagttctgaaggtagtaagaaggaaatgaggagtagtgttaggaaggggctaacttttttcttcttgcttc tcttctttatctcacctgcccctccccttgtatcccttcttcctttttccctttccttttttgtcctcacttcattcgtg catcctttctgattcctcttaccttgctaaaaggagaagtttgtttgggtatcctatatcaatggcaggaaggttgtttt cttctttacctttatcctatagattcatattctcaacaccaacctcctcctttttcagtttccttcttgcttctcttgac accacagagtttgcagctagtacttggagaggaaaattaaacagagatacttggaccaagagtaagatgaagaaagtcta aacaacagtatagtctatagtggcaagagagagtatgggggctgcttagccagggtggctgtacataaagtatatcttca gtttatataaactgcttatagatggaaatcagaaaatttaaattctcttaactgtccaagaaaattctcattttttcaaa tttgggactgataaatgtgaccagttctgcttactgtccattgcctgaaatggagctttgaggtggactgtataatttct tcaatcttaactccaaattctgatcagcgacgccctctgctgttcactattaatatttatttaccaatcaaagtaaagta ttgaagttttcctggcagttttcactttgtgttttagtccatttaggctgctataacaaaatcccttaaactgggtaagg gattataaatattagaaatttatctctcacagttctggaagctgggaagcccaatatcaaggcaccagtagatttggtgt ctaacgagggtgtgccgtctgcttcaaaaatggccccttgttgctgcatcctcacttagtgcaaggggcaagacagctcc cttcaacctcttttataagggcacttatgtcattcatgagggcagagccctcatgacttaatcacttccccaaaggcccc acctcttaatagtatcacattgggtgttaggtgtctgggaggacaccaatcttcaagccatatcatctcacttggaaaaa agtcaaaataaaaccagtagatttaattaatattacactatttatagaagcatgtgatgtatcattccttgtattaattt cctggggttgccgtaacaagttaccacaaactaggtggcttaaaacaatagaattttattctctcacatttctagaggca gaagttcacagtgtgtcaatagggccatgttctctggaaggctttaggggagaatatatttcatatctttctcttagctt ctcggtgtcactggcaatccttagcttactttggctttctgtgtcttcacatcatctttttataagaacaccagtgatag tgattaagggcataccttactttaatatgacctcatcttaactaattatgtcttcaataaccctatttccaaataaggcc acattctgaagtattgggagttagaacttaaagctttttgggagggacacagttcaacccataacaacccctaaaatcga tatttattctcaattaagtcttgaaattggtttcaaaaagagaatattctattagagtttttaatgtatagttttaacat atagttctttagcccccaattttttttttttttttttttttttttttttttttttgagacggagtctcgctctgtcgccc aggccggactgcggactgcagtggcgcaatctcggctcactgcaagctccgcttcccgggttcacgccattcccctgcct cagcctcccgagtagctgggactacaggcgcctgccaccgcgcccggctaatttttttgtatttttagtagagacggggt ttcaccttgttagccaggatggtctcgatctcctgacctcatgatccacccgcctcggcctcccaaagtgctgggattac aggcgtgagccaccgcgcccggcctgcccccaattatttagtttttctataaacagggaaatttatttgtgtggccctta gaactaatttaatttccactctaattcctacttatgtttatataatgcttttagaaatttgtattattcagaaaataaac atatactattgtatctgttgcctacacttagattttattgcctgctatatttaaattttattagtattttaattgtttta ttaaagaaagaatgtgcctgtaatctcagcacttttgagaggccaaggcagaaggattgcttgagcccaggagtttgaga ccagactgagcaacacagggagacccccatctctacaaaaaataaaaaaattctccaggcctcatggcacatacctgtag ttctagttacttgggagactggggtgggaggatgcattgagcccaggagattgaggctgcagtgagccatgatcaggcca ctgtactccagcttggacaacagagtgagagcttgtctagatagatagatagatagataatctaaatagataatagacag attatctaaatagataatagacagattatctaaatagataatagacagattatctaaatagataatagacagatta cta aatagataatagacagattatctaaatagataatagacagattatctatctaaatagataatagattatctaaatagata atagatagatagattagatagatagatagatagatagagcttggacaacagagtgagagcctgtctagatagatagaaac aaagaaagaaagaaagaatggtgctcatattttaaagcattgaaaaatggtcttccttgcttatattacccacaccttct ttgttggcattaagatgcaaactttgttttaaacagttgagtaaatcaaagatgggactgttaagttatttgtgttattt acctgctttttgaaaatgtaaaaataaaactctaggtttaattagtagtatgctatttagtaatgaagtaaagctagagg cttcgaacaaatcttgtgtaatttcctcttgaatgagagagaaaatttaaagtaagcaaacaaataagttgtgtgtcacc actcattcagtcatttaacaagtatttccagagtacttattctgtgccaggaaatgttgtaggtgccctcaacaacttag agtctagcctgagacacaagtaagtaggtaattattatagaatggtatgatctttggaggactgggtattggctggctca tgggagtacaagataggtacccagtgatgaagtcaggaaaggtttcttatggtgatatgatgacgtctatgctgattata aggtcagtgtagaataaactttgtgcttttaaatttgcatagcactgtattagagagttcatcttcaaaataatcgaaaa ggctgagtgtggtgacccatggctgtaatcccagcactttgggaggccgaggtgggcagattgcttgagctaggagttcg agaccaggctggccaacatggtgaaaccccgtctctactaaaaatacaaaaattagccaggagtgatggtgcgcacctgt aatgccagctacttgggaggctgaggcaggaggatcacttgaacccaggaggtggaggttgaagtaagccgaggtcatgc cactgcactccagcctgggcaacagagtgagactccatctcaaaaaaaaaaaaaatgatcaaagaaaggtgaattttcat ctaccctatttctgctgaggaaaatggactattttcaaatatttttaataagggtcaaaatgagggatc (SEQ ID NO: 12088) atttttttgtagagacagggtctctctatgttgcccaggctggtttcaaactcccaggctcaagcaatcctcctgccttg gcctcccaaagtgctggcattacaggcgtgagccactgcgcctggcccgtattaatgtttagaacacgaattccaggagg caggctaagtctattcagcttgttcatatgcttgggccaacccaagaaacaagtgggtgacaaatggcaccttttggata gtggtattgactttgaaagtttgggtcaggaagctggggaggaagggtgggcaggctgtgggcagtcctgggcggaagac caggcagggctatgtgctcactgagcctccgccctcttcctttgaatctctgatagacttctgcctcctacttctccttt tctgcccttctttgctttggtggcttccttgtggttcctcagtggtgcctgcaacccctggttcacctccttccaggttc tggctccttccagccatggctctcagagtccttctgttaacaggtgcatgggg (SEQ ID Nθ:12089) gaattccgtggttcctcagtggtgcctgcaacccctggttcacctccttccaggttctggctccttccagccatggctct cagagtccttctgttaacagccttgaccttatgtcatgggttcaacttggacactgaaaacgcaatgaccttccaagaga acgcaaggggcttcgggcagagcgtggtccagcttcagggatccagggtggtggttggagccccccaggagatagtggct gccaaccaaaggggcagcctctaccagtgcgactacagcacaggctcatgcgagcccatccgcctgcaggtccccgtgga ggccgtgaacatgtccctgggcctgtccctggcagccaccaccagcccccctcagctgctggcctgtggtcccaccgtgc accagacttgcagtgagaacacgtatgtgaaagggctctgcttcctgtttggatccaacctacggcagcagccccagaag ttcccagaggccctccgagggtgtcctcaagaggatagtgacattgccttcttgattgatggctctggtagcatcatccc acatgactttcggcggatgaaggagtttgtctcaactgtgatggagcaattaaaaaagtccaaaaccttgttctctttga tgcagtactctgaagaattccggattcactttaccttcaaagagttccagaacaaccctaacccaagatcactggtgaag ccaataacgcagctgcttgggcggacacacacggccacgggcatccgcaaagtggtacgagagctgtttaacatcaccaa cggagcccgaaagaatgcctttaagatcctagttgtcatcacggatggagaaaagtttggcgatcccttgggatatgagg atgtcatccctgaggcagacagagagggagtcattcgctacgtcattggggtgggagatgccttccgcagtgagaaatcc cgccaagagcttaataccatcgcatccaagccgcctcgtgatcacgtgttccaggtgaataactttgaggctctgaagac cattcagaaccagcttcgggagaagatctttgcgatcgagggtactcagacaggaagtagcagctcctttgagcatgaga tgtctcaggaaggcttcagcgctgccatcacctctaatggccccttgctgagcactgtggggagctatgactgggctggt ggagtctttctatatacatcaaaggagaaaagcaccttcatcaacatgaccagagtggattcagacatgaatgatgctta cttgggttatgctgccgccatcatcttacggaaccgggtgcaaagcctggttctgggggcacctcgatatcagcacatcg gcctggtagcgatgttcaggcagaacactggcatgtgggagtccaacgctaatgtcaagggcacccagatcggcgcctac ttcggggcctccctctgctccgtggacgtggacagcaacggcagcaccgacctggtcctcatcggggccccccattacta cgagcagacccgagggggccaggtgtccgtgtgccccttgcccagggggcagagggctcggtggcagtgtgatgctgttc tctacggggagcagggccaaccctggggccgctttggggcagccctaacagtgctgggggacgtaaatggggacaagctg acggacgtggccattggggccccaggagaggaggacaaccggggtgctgtttacctgtttcacggaacctcaggatctgg catcagcccctcccatagccagcggatagcaggctccaagctctctcccaggctccagtattttggtcagtcactgagtg ggggccaggacctcacaatggatggactggtagacctgactgtaggagcccaggggcacgtgctgctgctcaggtcccag ccagtactgagagtcaaggcaatcatggagttcaatcccagggaagtggcaaggaatgtatttgagtgtaatgatcaggt ggtgaaaggcaaggaagccggagaggtcagagtctgcctccatgtccagaagagcacacgggatcggctaagagaaggac agatccagagtgttgtgacttatgacctggctctggactccggccgcccacattcccgcgccgtcttcaatgagacaaag aacagcacacgcagacagacacaggtcttggggctgacccagacttgtgagaccctgaaactacagttgccgaattgcat cgaggacccagtgagccccattgtgctgcgcctgaacttctctctggtgggaacgccattgtctgctttcgggaacctcc ggccagtgctggcggaggatgctcagagactcttcacagccttgtttccctttgagaagaattgtggcaatgacaacatc tgccaggatgacctcagcatcaccttcagtttcatgagcctggactgcctcgtggtgggtgggccccgggagttcaacgt gacagtgactgtgagaaatgatggtgaggactcctacaggacacaggtcaccttcttcttcccgcttgacctgtcctacc ggaaggtgtccacactccagaaccagcgctcacagcgatcctggcgcctggcctgtgagtctgcctcctccaccgaagtg tctggggccttgaagagcaccagctgcagcataaaccaccccatcttcccggaaaactcagaggtcacctttaatatcac gtttgatgtagactctaaggcttcccttggaaacaaactgctcctcaaggccaatgtgaccagtgagaacaacatgccca gaaccaacaaaaccgaattccaactggagctgccggtgaaatatgctgtctacatggtggtcaccagccatggggtctcc actaaatatctcaacttcacggcctcagagaataccagtcgggtcatgcagcatcaatatcaggtcagcaacctggggca gaggagcctccccatcagcctggtgttcttggtgcccgtccggctgaaccagactgtcatatgggaccgcccccaggtca ccttctccgagaacctctcgagtacgtgccacaccaaggagcgcttgccctctcactccgactttctggctgagcttcgg aaggcccccgtggtgaactgctccatcgctgtctgccagagaatccagtgtgacatcccgttctttggcatccaggaaga attcaatgctaccctcaaaggcaacctctcgtttgactggtacatcaagacctcgcataaccacctcctgatcgtgagca cagctgagatcttgtttaacgattccgtgttcaccctgctgccgggacagggggcgtttgtgaggtcccagacggagacc aaagtggagccgttcgaggtccccaaccccctgccgctcatcgtgggcagctctgtcgggggactgctgctcctggccct catcaccgccgcgctgtacaagctcggcttcttcaagcggcaatacaaggacatgatgagtgaagggggtcccccggggg ccgaaccccagtagcggctccttcccgacagagctgcctctcggtggccagcaggactctgcccagaccacacgtagccc ccaggctgctggacacgtcggacagcgaagtatccccgacaggacgggcttgggcttccatttgtgtgtgtgcaagtgtg tatgtgcgtgtgtgcgagtgtgtgcaagtgtctgtgtgcaagtgtgtgcacgtgtgcgtgtgcgtgcatgtgcactcgca cgcccatgtgtgagtgtgtgcaagtatgtgagtgtgtccagtgtgtgtgcgtgtgtccatgtgtgtgcagtgtgtgcatg tgtgcgagtgtgtgcatgtgtgtgctcaggggctgtggctcacgtgtgtgactcagagtgtctctggcgtgtgggtaggt gacggcagcgtagcctctccggcagaagggaactgcctgggctcccttgtgcgtgggtaagccgctgctgggttttcctc cgggagaggggacggtcaatcctgtgggtgaagagagagggaaacacagcagcatctctccactgaaagaagtgggactt cccgtcgcctgcgagcctgcggcctgctggagcctgcgcagcttggatggatactccatgagaaaagccgtgggtggaac caggagcctcctccacaccagcgctgatgcccaataaagatgcccactgaggaatcatgaagcttcctttctggattcat ttattatttcaatgtgactttaattttttggatggataagcctgtctatggtacaaaaatcacaaggcattcaagtgtac agtgaaaagtctccctttccagatattcaagtcacctccttaaaggtagtcaagattgtgttttgaggtttccttcagac agattccaggcgatgtgcaagtgtatgcacgtgtgcacacaccacacacatacacacacacaagcttttttacacaaatg gtagcatactttatattggtctgtatcttgctttttttcaccaatatttctcagacatcggttcatattaagacataaat tactttttcattcttttataccgctgcatagtattccattgtgtgagtgtaccataatgtatttaaccagtcttcttttg atatactattttcatctcttgttattgcatctgctgagttaataaatcaaatatatgtcaaaaaaaaaaaaaaaaaaaaa aaaaaaaaaaaaaaaaaaaa (SEQ ID NO:12090) ggttcaagtgattctgctgcctcagcctcccaggcgggattacaggtgcctgccaccacgcctggctaatttttttgtct ttttagtaaagatgaggtttcaccatgttgggcaggctggtttcaattgctgacctcaagtgagccaccccgcctcagcc tccaaaatgctaggattacaggcatgagccaccgcacccagccaagtttgtacatatatttttgactacacttcttaact attcttaggataaattactagaagtgaaaattcttgggtgaagagcttgaggcctttacacacacacacacacacacaca cacacacacacaaataggctggatcgagtggctcacacctgtaatctcagcagtttgggaggctgaggaaggaggatcac ttgagtccaggaggttgagaatagcctgaacaacatagcaagatcttgtctctacaaaaaagtttaaaaaaaattagctg gccatggcagcatgtgcctgtagtaccagctactcggaaggctgaggtaggaggatcgcttgagcccaggaggtgattga agctgcagtgagctgtgattacaccactgcactccagcctgggcaacagagctagactctgtctctaaaaaaaggcacaa aataatatttaaaaagcaccaggtatgcctgtacttgagttgtctttgttgatggctacaaatgagacagctctggctga agggcggcttccatttccatgggctggaggaggacattttgcaaagtgtgttttcaggaagacacagagttttacctcct acacttgtttgatctgtattaatgtttgcttatttatttatttaattttttttttgagacagagtctcactctgtcacct gggctggagtgcagtggcattattgaggctcattgcagtctcagactcctgagctcaaacaatcctcctgcctcagcctc tggagtagctaggactacaggcatgtgccaccatgcctggctaattttttaaatgtatttttttgtagagtcggggtctc cctatgttgcccaggctggagtgcagtggtgtgatcctagctcactgcagcctggacctcgggctcaagaaattctcaca cctcagcctgtccagtagcaggggctacaggcgcgcaccaccatcccagctaattaaaaatatttttttgtagagacagg gtctctctatgttgcccaggctggtttcaaactcccaggctcaagcaatcctcctgccttgcctcccaaatgacatcgga ttacaggcgtgagccactgagcctggcccgtattaatgtttagaacacgaattccaggaggcaggctaagtctattcagc ttgttcatatgcttgggccaacccaagaaacaagtgggtgacaaatggcaccttttggatagtggtattgactttgaaag tttgggtcaggagctggggaggaagggtgggcaggctgtgggcagtcctgggcggaagaccaggcagggctatgtgctca ctgagcctccgccctcttcctttgaatctctgatagacttctgcctcctacttctccttttctgcccttctttgctttgg tggcttccttgtggttcctcagtggtgcctgcaaccctggttcactcttccaggttctggctccttccagccatggctct cagagtccttctgttaacaggtgcatgggggtggggtgggggactctgggtggggaggagggtaacttttgggtctgtca taaatagagggccc (SEQ ID NO: 12091) atttttttgtagagacagggtctctctatgttgcccaggctggtttcaaactcccaggctcaagcaatcctcctgccttg gcctcccaaagtgctggcattacaggcgtgagccactgcgcctggcccgtattaatgtttagaacacgaattccaggagg caggctaagtctattcagcttgttcatatgcttgggccaacccaagaaacaagtgggtgacaaatggcaccttttggata gtggtattgactttgaaagtttgggtcaggaagctggggaggaagggtgggcaggctgtgggcagtcctgggcggaagac caggcagggctatgtgctcactgagcctccgccctcttcctttgaatctctgatagacttctgcctcctacttctccttt tctgcccttctttgctttggtggcttccttgtggttcctcagtggtgcctgcaacccctggttcacctccttccaggttc tggctccttccagccatggctctcagagtccttctgttaacaggtgcatgggggaattccgtggttcctcagtggtgcct gcaacccctggttcacctccttccaggttctggctccttccagccatggctctcagagtccttctgttaacagccttgac cttatgtcatgggttcaacttggacactgaaaacgcaatgaccttccaagagaacgcaaggggcttcgggcagagcgtgg tccagcttcagggatccagggtggtggttggagccccccaggagatagtggctgccaaccaaaggggcagcctctaccag tgcgactacagcacaggctcatgcgagcccatccgcctgcaggtccccgtggaggccgtgaacatgtccctgggcctgtc cctggcagccaccaccagcccccctcagctgctggcctgtggtcccaccgtgcaccagacttgcagtgagaacacgtatg tgaaagggctctgcttcctgtttggatccaacctacggcagcagccccagaagttcccagaggccctccgagggtgtcct caagaggatagtgacattgccttcttgattgatggctctggtagcatcatcccacatgactttcggcggatgaaggagtt tgtctcaactgtgatggagcaattaaaaaagtccaaaaccttgttctctttgatgcagtactctgaagaattccggattc actttaccttcaaagagttccagaacaaccctaacccaagatcactggtgaagccaataacgcagctgcttgggcggaca cacacggccacgggcatccgcaaagtggtacgagagctgtttaacatcaccaacggagcccgaaagaatgcctttaagat cctagttgtcatcacggatggagaaaagtttggcgatcccttgggatatgaggatgtcatccctgaggcagacagagagg gagtcattcgctacgtcattggggtgggagatgccttccgcagtgagaaatcccgccaagagcttaataccatcgcatcc aagccgcctcgtgatcacgtgttccaggtgaataactttgaggctctgaagaccattcagaaccagcttcgggagaagat ctttgcgatcgagggtactcagacaggaagtagcagctcctttgagcatgagatgtctcaggaaggcttcagcgctgcca tcacctctaatggccccttgctgagcactgtggggagctatgactgggctggtggagtctttctatatacatcaaaggag aaaagcaccttcatcaacatgaccagagtggattcagacatgaatgatgcttacttgggttatgctgccgccatcatctt acggaaccgggtgcaaagcctggttctgggggcacctcgatatcagcacatcggcctggtagcgatgttcaggcagaaca ctggcatgtgggagtccaacgctaatgtcaagggcacccagatcggcgcctacttcggggcctccctctgctccgtggac gtggacagcaacggcagcaccgacctggtcctcatcggggccccccattactacgagcagacccgagggggccaggtgtc cgtgtgccccttgcccagggggcagagggctcggtggcagtgtgatgctgttctctacggggagcagggccaaccctggg gccgctttggggcagccctaacagtgctgggggacgtaaatggggacaagctgacggacgtggccattggggccccagga gaggaggacaaccggggtgctgtttacctgtttcacggaacctcaggatctggcatcagcccctcccatagccagcggat agcaggctccaagctctctcccaggctccagtattttggtcagtcactgagtgggggccaggacctcacaatggatggac tggtagacctgactgtaggagcccaggggcacgtgctgctgctcaggtcccagccagtactgagagtcaaggcaatcatg gagttcaatcccagggaagtggcaaggaatgtatttgagtgtaatgatcaggtggtgaaaggcaaggaagccggagaggt cagagtctgcctccatgtccagaagagcacacgggatcggctaagagaaggacagatccagagtgttgtgacttatgacc tggctctggactccggccgcccacattcccgcgccgtcttcaatgagacaaagaacagcacacgcagacagacacaggtc ttggggctgacccagacttgtgagaccctgaaactacagttgccgaattgcatcgaggacccagtgagccccattgtgct gcgcctgaacttctctctggtgggaacgccattgtctgctttcgggaacctccggccagtgctggcggaggatgctcaga gactcttcacagccttgtttccctttgagaagaattgtggcaatgacaacatctgccaggatgacctcagcatcaccttc agtttcatgagcctggactgcctcgtggtgggtgggccccgggagttcaacgtgacagtgactgtgagaaatgatggtga ggactcctacaggacacaggtcaccttcttcttcccgcttgacctgtcctaccggaaggtgtccacactccagaaccagc gctcacagcgatcctggcgcctggcctgtgagtctgcctcctccaccgaagtgtctggggccttgaagagcaccagctgc agcataaaccaccccatcttcccggaaaactcagaggtcacctttaatatcacgtttgatgtagactctaaggcttccct tggaaacaaactgctcctcaaggccaatgtgaccagtgagaacaacatgcccagaaccaacaaaaccgaattccaactgg agctgccggtgaaatatgctgtctacatggtggtcaccagccatggggtctccactaaatatctcaacttcacggcctca gagaataccagtcgggtcatgcagcatcaatatcaggtcagcaacctggggcagaggagcctccccatcagcctggtgtt cttggtgcccgtccggctgaaccagactgtcatatgggaccgcccccaggtcaccttctccgagaacctctcgagtacgt gccacaccaaggagcgcttgccctctcactccgactttctggctgagcttcggaaggcccccgtggtgaactgctccatc gctgtctgccagagaatccagtgtgacatcccgttctttggcatccaggaagaattcaatgctaccctcaaaggcaacct ctcgtttgactggtacatcaagacctcgcataaccacctcctgatcgtgagcacagctgagatcttgtttaacgattccg tgttcaccctgctgccgggacagggggcgtttgtgaggtcccagacggagaccaaagtggagccgttcgaggtccccaac cccctgccgctcatcgtgggcagctctgtcgggggactgctgctcctggccctcatcaccgccgcgctgtacaagctcgg cttcttcaagcggcaatacaaggacatgatgagtgaagggggtcccccgggggccgaaccccagtagcggctccttcccg acagagctgcctctcggtggccagcaggactctgcccagaccacacgtagcccccaggctgctggacacgtcggacagcg aagtatccccgacaggacgggcttgggcttccatttgtgtgtgtgcaagtgtgtatgtgcgtgtgtgcgagtgtgtgcaa gtgtctgtgtgcaagtgtgtgcacgtgtgcgtgtgcgtgcatgtgcactcgcacgcccatgtgtgagtgtgtgcaagtat gtgagtgtgtccagtgtgtgtgcgtgtgtccatgtgtgtgcagtgtgtgcatgtgtgcgagtgtgtgcatgtgtgtgctc aggggctgtggctcacgtgtgtgactcagagtgtctctggcgtgtgggtaggtgacggcagcgtagcctctccggcagaa gggaactgcctgggctcccttgtgcgtgggtaagccgctgctgggttttcctccgggagaggggacggtcaatcctgtgg gtgaagagagagggaaacacagcagcatctctccactgaaagaagtgggacttcccgtcgcctgcgagcctgcggcctgc tggagcctgcgcagcttggatggatactccatgagaaaagccgtgggtggaaccaggagcctcctccacaccagcgctga tgcccaataaagatgcccactgaggaatcatgaagcttcctttctggattcatttattatttcaatgtgactttaatttt ttggatggataagcctgtctatggtacaaaaatcacaaggcattcaagtgtacagtgaaaagtctccctttccagatatt caagtcacctccttaaaggtagtcaagattgtgttttgaggtttccttcagacagattccaggcgatgtgcaagtgtatg cacgtgtgcacacaccacacacatacacacacacaagcttttttacacaaatggtagcatactttatattggtctgtatc ttgctttttttcaccaatatttctcagacatcggttcatattaagacataaattactttttcattcttttataccgctgc atagtattccattgtgtgagtgtaccataatgtatttaaccagtcttcttttgatatactattttcatctcttgttattg catctgctgagttaataaatcaaatatatgtcaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaggttcaa gtgattctgctgcctcagcctcccaggcgggattacaggtgcctgccaccacgcctggctaatttttttgtctttttagt aaagatgaggtttcaccatgttgggcaggctggtttcaattgctgacctcaagtgagccaccccgcctcagcctccaaaa tgctaggattacaggcatgagccaccgcacccagccaagtttgtacatatatttttgactacacttcttaactattctta ggataaattactagaagtgaaaattcttgggtgaagagcttgaggcctttacacacacacacacacacacacacacacac acacaaataggctggatcgagtggctcacacctgtaatctcagcagtttgggaggctgaggaaggaggatcacttgagtc caggaggttgagaatagcctgaacaacatagcaagatcttgtctctacaaaaaagtttaaaaaaaattagctggccatgg cagcatgtgcctgtagtaccagctactcggaaggctgaggtaggaggatcgcttgagcccaggaggtgattgaagctgca gtgagctgtgattacaccactgcactccagcctgggcaacagagctagactctgtctctaaaaaaaggcacaaaataata tttaaaaagcaccaggtatgcctgtacttgagttgtctttgttgatggctacaaatgagacagctctggctgaagggcgg cttccatttccatgggctggaggaggacattttgcaaagtgtgttttcaggaagacacagagttttacctcctacacttg tttgatctgtattaatgtttgcttatttatttatttaattttttttttgagacagagtctcactctgtcacctgggctgg agtgcagtggcattattgaggctcattgcagtctcagactcctgagctcaaacaatcctcctgcctcagcctctggagta gctaggactacaggcatgtgccaccatgcctggctaattttttaaatgtatttttttgtagagtcggggtctccctatgt tgcccaggctggagtgcagtggtgtgatcctagctcactgcagcctggacctcgggctcaagaaattctcacacctcagc ctgtccagtagcaggggctacaggcgcgcaccaccatcccagctaattaaaaatatttttttgtagagacagggtctctc tatgttgcccaggctggtttcaaactcccaggctcaagcaatcctcctgccttgcctcccaaatgacatcggattacagg cgtgagccactgagcctggcccgtattaatgtttagaacacgaattccaggaggcaggctaagtctattcagcttgttca tatgcttgggccaacccaagaaacaagtgggtgacaaatggcaccttttggatagtggtattgactttgaaagtttgggt caggagctggggaggaagggtgggcaggctgtgggcagtcctgggcggaagaccaggcagggctatgtgctcactgagcc tccgccctcttcctttgaatctctgatagacttctgcctcctacttctccttttctgcccttctttgctttggtggcttc cttgtggttcctcagtggtgcctgcaaccctggttcactcttccaggttctggctccttccagccatggctctcagagtc cttctgttaacaggtgcatgggggtggggtgggggactctgggtggggaggagggtaacttttgggtctgtcataaatag agggccc (SEQ ID NO: 12092) ctgcagctccggaacgggggggggctgctctccaccgcccctgtgcggccgcccgggaaagtgcaggcgggccgggcgcg gtggctcacgcctgtgatctcagcactttgggaggccgaggtgggcggatcacctgaggtcgggagttcgaggccagcct gcccaacatggagaaaccctgtctctactaaagatacaaaattagccaggcgtggtgacgcatgcctgtaatcccagcta ctggagtggctgaggcaggagaatcgcttgagcccgggagacagaggttgcggtgagctgagatcgcaccattgcactcc agcctgggcaacaagagcgaaactcagaaaaaaaagaaaagaaagtgcaggggacccgccgtcggggtgggggcggcgct gcccagcctctgtcccacttccatgcacttgacctcgaccctccggcctccgtctgcgatcttcccgtgcctgaatatga ggcttggaacagacccagaccttcctgcctgcccgtcctgagtggccccgggaccccgccccatctttggcccccagccc ctgcctctctgccgcctccagggtcgggggtcaggccaggaaagccccttgggaagcccccggggagcagctggagcggg gtcgccgggcggcgggaaggagtgggcgcctctatttaagcggcttccccgcggcctcgggacagaggggactgagcatg gatttcggactggccctcctgctggcggggcttctggggctcctcctcggtgagaaggg (SEQ ID NO: 12093) atggatttcggactggccctcctgctggcggggcttctggggctcctcctcggccagtccctccaggtgaagcccctgca ggtggagcccccggagccggtggtggccgtggccttgggcgcctcgcgccagctcacctgccgcctggcctgcgcggacc gcggggcctcggtgcagtggcggggcctggacaccagcctgggcgcggtgcagtcggacacgggccgcagcgtcctcacc gtgcgcaacgcctcgctgtcggcggccgggacccgcgtgtgcgtgggctcctgcgggggccgcaccttccagcacaccgt gcagctccttgtgtacgccttcccggaccagctgaccgtctccccagcagccctggtgcctggtgacccggaggtggcct gtacggcccacaaagtcacgcccgtggaccccaacgcgctctccttctccctgctcgtcgggggccaggaactggagggg gcgcaagccctgggcccggaggtgcaggaggaggaggaggagccccagggggacgaggacgtgctgttcagggtgacaga gcgctggcggctgccgcccctggggacccctgtcccgcccgccctctactgccaggccacgatgaggctgcctggcttgg agctcagccaccgccaggccatccccgtcctgcacagcccgacctccccggagcctcccgacaccacctccccggagcct cccaacaccacctccccggagtctcccgacaccacctccccggagtctcccgacaccacctcccaggagcctcccgacac cacctcccaggagcctcccgacaccacctcccaggagcctcccgacaccacctccccggagcctcccgacaagacctccc cggagcccgccccccagcagggctccacacacacccccaggagcccaggctccaccaggactcgccgccctgagatctcc caggctgggcccacgcagggagaagtgatcccaacaggctcgtccaaacctgcgggtgaccagctgcccgcggctctgtg gaccagcagtgcggtgctgggactgctgctcctggccttgcccacgtatcacctctggaaacgctgccggcacctggctg aggacgacacccacccaccagcttctctgaggcttctgccccaggtgtcggcctgggctgggttaagggggaccggccag gtcgggatcagcccctcctgagtggccagcctttccccctgtgaaagcaaaatagcttggaccccttcaagttgagaact ggtcagggcaaacctgcctcccattctactcaaagtcatccctctgctcacagagatggatgcatgttctgattgcctct ttggagaagctcatcagaaactcaaaagaaggccactgtttgtctcacctacccatgacctgaagcccctccctgagtgg tccccacctttctggacggaaccacgtactttttacatacattgattcatgtctcacgtctccctaaaaatgcgtaagac caagctgtgccctgaccaccctgggcccctgtcgtcaggacctcctgaggctttggcaaataaacctcctaaaatgat (SEQ ID NO:1209₄) tccatcacagccttcccggaccagctgaccgtctccccagcagccctggtgcctggtgacccggaggtggcctgtacggc ccacaaagtcacgcccgtggaccccaacgcgctctccttctccctgctcgtcgggggccaggaactggagggggcgcaag ccctgggcccggaggtgcaggaggaggaggaggagccccagggggacgaggacgtgctgttcagggtgacagagcgctgg 5 cggctgccgcccctggggacccctgtcccgcccgccctctactgccaggccacgatgaggctgcctggcttggagctcag ccaccgccaggccatccccggtgagtccgc (SEQ ID NO: 12095) gtcgccgcaggccagtccctccaggtgaagcccctgcaggtggagcccccggagccggtggtggccgtggccttgggcgc ctcgcgccagctcacctgccgcctggcctgcgcggaccgcggggcctcggtgcagtggcggggcctggacaccagcctgg gcgcggtgcagtcggacacgggccgcagcgtcctcaccgtgcgcaacgcctcgctgtcggcggccgggacccgcgtgtgc

10 gtgggctcctgcgggggccgcaccttccagcacaccgtgcagctccttgtgtacggtgaggcgtc (SEQ ID NO:12096) ctgtttccagtcctgcacagcccgacctccccggagcctcccgacaccacctccccggagcctcccaacaccacctcccc ggagtctcccgacaccacctccccggagtctcccgacaccacctcccaggagcctcccgacaccacctcccaggagcctc ccgacaccacctcccaggagcctcccgacaccacctccccggagcctcccgacaagacctccccggagcccgccccccag cagggctccacacacacccccaggagcccaggctccaccaggactcgccgccctgagatctcccaggctgggcccacgca

15 gggagaagtgatcccaacaggctgtgagttctg (SEQ ID NO: 12097) ctctccccagcgtccaaacctgcgggtgaccagctgcccgcggctctgtggaccagcagtgcggtgctgggactgctgct cctggccttgcccacgtatcacctctggaaacgctgccggcacctggctgaggacgacacccacccaccagcttctctga ggcttctgccccaggtgtcggcctgggctgggttaagggggaccggccaggtcgggatcagcccctcctgagtggccagc ctttccccctgtgaaagcaaaatagcttggaccccttcaagttgagaactggtcagggcaaacctgcctcccattctact

20 caaagtcatccctctgttcacagagatggatgcatgttctgattgcctctttggagaagctcatcagaaactcaaaagaa ggccactgtttgtctcacctacccatgacctgaagcccctccctgagtggtccccacctttctggacggaaccacgtact ttttacatacattgattcatgtctcacgtctccctaaaaatgcgtaagaccaagctgtgccctgaccaccctgggcccct gtcgtcaggacctcctgaggctttggcaaataaacctcctaaaatgat (SEQ ID NO: 12098) gggactgagcatggatttcggactggccctcctgctggcggggcttctggggctcctcctcggccagtccctccaggtga

25. agcccctgcaggtggagcccccggagccggtggtggccgtggccttgggcgcctcgcgccagctcacctgccgcctggcc tgcgcggaccgcggggcctcggtgcagtggcggggcctggacaccagcctgggcgcggtgcagtcggacacgggccgcag cgtcctcaccgtgcgcaacgcctcgctgtcggcggccgggacccgcgtgtgcgtgggctcctgcgggggccgcaccttcc agcacaccgtgcagctccttgtgtacgccttcccggaccagctgaccgtctccccagcagccctggtgcctggtgacccg gaggtggcctgtacggcccacaaagtcacgcccgtggaccccaacgcgctctccttctccctgctcgtcgggggccagga

30 actggagggggcgcaagccctgggcccggaggtgcaggaggaggaggaggagccccagggggacgaggacgtgctgttca gggtgacagagcgctggcggctgccgcccctggggacccctgtcccgcccgccctctactgccaggccacgatgaggctg cctggcttggagctcagccaccgccaggccatccccgtcctgcacagcccgacctccccggagcctcccgacaccacctc cccggagtctcccgacaccacctccccggagtctcccgacaccacctccccggagcctcccgacaccacctccccggagc ctcccgacaagacctccccggagcccgccccccagcagggctccacacacacccccaggagcccaggctccaccaggact

35 cgccgccctgagatctcccaggctgggcccacgcagggagaagtgatcccaacaggctcgtccaaacctgcgggtgacca gctgcccgcggctctgtggaccagcagtgcggtgctgggactgctgctcctggccttgcccacgtatcacctctggaaac gctgccggcacctggctgaggacgacacccacccaccagcttctctgaggcttctgccccaggtgtcggcctgggctggg ttaagggggaccggccaggtcgggatcagcccctcctgagtggccagcctttccccctgtgaaagcaaaatagcttggac cccttcaagttgagaactggtcagggcaaacctgcctcccattctactcaaagtcatccctctgttcacagagatggatg

40 catgttctgattgcctctttggagaagctcatcagaaactcaaaagaaggccactgtttgtctcacctacccatgacctg aagcccctccctgagtggtccccacctttctggacggaaccacgtactttttacatacattgattcatgtctcacgtctc cctaaaaatgcgtaagaccaagctgtgccctgaccaccctgggcccctgtcgtcaggacctcctgaggctttggcaaata aacctcctaaaatgataaaaaaaaaa (SEQ ID NO: 12099) ctgcagctccggaacgggggggggctgctctccaccgcccctgtgcggccgcccgggaaagtgcaggcgggccgggcgcg

45 gtggctcacgcctgtgatctcagcactttgggaggccgaggtgggcggatcacctgaggtcgggagttcgaggccagcct gcccaacatggagaaaccctgtctctactaaagatacaaaattagccaggcgtggtgacgcatgcctgtaatcccagcta ctggagtggctgaggcaggagaatcgcttgagcccgggagacagaggttgcggtgagctgagatcgcaccattgcactcc agcctgggcaacaagagcgaaactcagaaaaaaaagaaaagaaagtgcaggggacccgccgtcggggtgggggcggcgct gcccagcctctgtcccacttccatgcacttgacctcgaccctccggcctccgtctgcgatcttcccgtgcctgaatatga

50 ggcttggaacagacccagaccttcctgcctgcccgtcctgagtggccccgggaccccgccccatctttggcccccagccc ctgcctctctgccgcctccagggtcgggggtcaggccaggaaagccccttgggaagcccccggggagcagctggagcggg gtcgccgggcggcgggaaggagtgggcgcctctatttaagcggcttccccgcggcctcgggacagaggggactgagcatg gatttcggactggccctcctgctggcggggcttctggggctcctcctcggtgagaagggatggatttcggactggccctc ctgctggcggggcttctggggctcctcctcggccagtccctccaggtgaagcccctgcaggtggagcccccggagccggt

55 ggtggccgtggccttgggcgcctcgcgccagctcacctgccgcctggcctgcgcggaccgcggggcctcggtgcagtggc ggggcctggacaccagcctgggcgcggtgcagtcggacacgggccgcagcgtcctcaccgtgcgcaacgcctcgctgtcg gcggccgggacccgcgtgtgcgtgggctcctgcgggggccgcaccttccagcacaccgtgcagctccttgtgtacgcctt cccggaccagctgaccgtctccccagcagccctggtgcctggtgacccggaggtggcctgtacggcccacaaagtcacgc ccgtggaccccaacgcgctctccttctccctgctcgtcgggggccaggaactggagggggcgcaagccctgggcccggag

60 gtgcaggaggaggaggaggagccccagggggacgaggacgtgctgttcagggtgacagagcgctggcggctgccgcccct ggggacccctgtcccgcccgccctctactgccaggccacgatgaggctgcctggcttggagctcagccaccgccaggcca tccccgtcctgcacagcccgacctccccggagcctcccgacaccacctccccggagcctcccaacaccacctccccggag tctcccgacaccacctccccggagtctcccgacaccacctcccaggagcctcccgacaccacctcccaggagcctcccga caccacctcccaggagcctcccgacaccacctccccggagcctcccgacaagacctccccggagcccgccccccagcagg

65 gctccacacacacccccaggagcccaggctccaccaggactcgccgccctgagatctcccaggctgggcccacgcaggga gaagtgatcccaacaggctcgtccaaacctgcgggtgaccagctgcccgcggctctgtggaccagcagtgcggtgctggg actgctgctcctggccttgcccacgtatcacctctggaaacgctgccggcacctggctgaggacgacacccacccaccag cttctctgaggcttctgccccaggtgtcggcctgggctgggttaagggggaccggccaggtcgggatcagcccctcctga gtggccagcctttccccctgtgaaagcaaaatagcttggaccccttcaagttgagaactggtcagggcaaacctgcctcc ₍

70 cattctactcaaagtcatccctctgctcacagagatggatgcatgttctgattgcctctttggagaagctcatcagaaac tcaaaagaaggccactgtttgtctcacctacccatgacctgaagcccctccctgagtggtccccacctttctggacggaa ccacgtactttttacatacattgattcatgtctcacgtctccctaaaaatgcgtaagaccaagctgtgccctgaccaccc tgggcccctgtcgtcaggacctcctgaggctttggcaaataaacctcctaaaatgattccatcacagccttcccggacca gctgaccgtctccccagcagccctggtgcctggtgacccggaggtggcctgtacggcccacaaagtcacgcccgtggacc

75 ccaacgcgctctccttctccctgctcgtcgggggccaggaactggagggggcgcaagccctgggcccggaggtgcaggag gaggaggaggagccccagggggacgaggacgtgctgttcagggtgacagagcgctggcggctgccgcccctggggacccc tgtcccgcccgccctctactgccaggccacgatgaggctgcctggcttggagctcagccaccgccaggccatccccggtg agtccgcgtcgccgcaggccagtccctccaggtgaagcccctgcaggtggagcccccggagccggtggtggccgtggcct tgggcgcctcgcgccagctcacctgccgcctggcctgcgcggaccgcggggcctcggtgcagtggcggggcctggacacc

80 agcctgggcgcggtgcagtcggacacgggccgcagcgtcctcaccgtgcgcaacgcctcgctgtcggcggccgggacccg cgtgtgcgtgggctcctgcgggggccgcaccttccagcacaccgtgcagctccttgtgtacggtgaggcgtcctgtttcc agtcctgcacagcccgacctccccggagcctcccgacaccacctccccggagcctcccaacaccacctccccggagtctc ccgacaccacctccccggagtctcccgacaccacctcccaggagcctcccgacaccacctcccaggagcctcccgacacc acctcccaggagcctcccgacaccacctccccggagcctcccgacaagacctccccggagcccgccccccagcagggctc cacacacacccccaggagcccaggctccaccaggactcgccgccctgagatctcccaggctgggcccacgcagggagaag tgatcccaacaggctgtgagttctgctctccccagcgtccaaacctgcgggtgaccagctgcccgcggctctgtggacca gcagtgcggtgctgggactgctgctcctggccttgcccacgtatcacctctggaaacgctgccggcacctggctgaggac gacacccacccaccagcttctctgaggcttctgccccaggtgtcggcctgggctgggttaagggggaccggccaggtcgg gatcagcccctcctgagtggccagcctttccccctgtgaaagcaaaatagcttggaccccttcaagttgagaactggtca gggcaaacctgcctcccattctactcaaagtcatccctctgttcacagagatggatgcatgttctgattgcctctttgga gaagctcatcagaaactcaaaagaaggccactgtttgtctcacctacccatgacctgaagcccctccctgagtggtcccc acctttctggacggaaccacgtactttttacatacattgattcatgtctcacgtctccctaaaaatgcgtaagaccaagc tgtgccctgaccaccctgggcccctgtcgtcaggacctcctgaggctttggcaaataaacctcctaaaatgatgggactg agcatggatttcggactggccctcctgctggcggggcttctggggctcctcctcggccagtccctccaggtgaagcccct gcaggtggagcccccggagccggtggtggccgtggccttgggcgcctcgcgccagctcacctgccgcctggcctgcgcgg accgcggggcctcggtgcagtggcggggcctggacaccagcctgggcgcggtgcagtcggacacgggccgcagcgtcctc accgtgcgcaacgcctcgctgtcggcggccgggacccgcgtgtgcgtgggctcctgcgggggccgcaccttccagcacac cgtgcagctccttgtgtacgccttcccggaccagctgaccgtctccccagcagccctggtgcctggtgacccggaggtgg cctgtacggcccacaaagtcacgcccgtggaccccaacgcgctctccttctccctgctcgtcgggggccaggaactggag ggggcgcaagccctgggcccggaggtgcaggaggaggaggaggagccccagggggacgaggacgtgctgttcagggtgac agagcgctggcggctgccgcccctggggacccctgtcccgcccgccctctactgccaggccacgatgaggctgcctggct tggagctcagccaccgccaggccatccccgtcctgcacagcccgacctccccggagcctcccgacaccacctccccggag tctcccgacaccacctccccggagtctcccgacaccacctccccggagcctcccgacaccacctccccggagcctcccga caagacctccccggagcccgccccccagcagggctccacacacacccccaggagcccaggctccaccaggactcgccgcc ctgagatctcccaggctgggcccacgcagggagaagtgatcccaacaggctcgtccaaacctgcgggtgaccagctgccc gcggctctgtggaccagcagtgcggtgctgggactgctgctcctggccttgcccacgtatcacctctggaaacgctgccg gcacctggctgaggacgacacccacccaccagcttctctgaggcttctgccccaggtgtcggcctgggctgggttaaggg ggaccggccaggtcgggatcagcccctcctgagtggccagcctttccccctgtgaaagcaaaatagcttggaccccttca agttgagaactggtcagggcaaacctgcctcccattctactcaaagtcatccctctgttcacagagatggatgcatgttc tgattgcctctttggagaagctcatcagaaactcaaaagaaggccactgtttgtctcacctacccatgacctgaagcccc tccctgagtggtccccacctttctggacggaaccacgtactttttacatacattgattcatgtctcacgtctccctaaaa atgcgtaagaccaagctgtgccctgaccaccctgggcccctgtcgtcaggacctcctgaggctttggcaaataaacctcc taaaatgataaaaaaaaaa (SEQ ID NO: 12100) ggaattccgggcccggtctttcctcccgccgccgccggcctggtcccggggactggcctccacgtccgactcgtccgagc tgaagcccagcagcactttgctgccagccgcgggggcggcggaggcgcccccgggccctcccaggaggctctctgggcca gaggccgagattcggcacaggcccccaggagtccgtaagtaggagaggtcgcccgagaccggccggacccccatccccgc ggccgccgccgccgctggtcccgcggctgcgaccgtggcggctgccgctggaaaatgtctcaggagaggcccacgttcta ccggcaggagctgaacaagacaatctgggaggtgcccgagcgttaccagaacctgtctccagtgggctctggcgcctatg gctctgtgtgtgctgcttttgacacaaaaacggggttacgtgtggcagtgaagaagctctccagaccatttcagtccatc attcatgcgaaaagaacctacagagaactgcggttacttaaacatatgaaacatgaaaatgtgattggtctgttggacgt ttttacacctgcaaggtctctggaggaattcaatgatgtgtatctggtgacccatctcatgggggcagatctgaacaaca ttgtgaaatgtcagaagcttacagatgaccatgttcagttccttatctaccaaattctccgaggtctaaagtatatacat tcagctgacataattcacagggacctaaaacctagtaatctagctgtgaatgaagactgtgagctgaagattctggattt tggactggctcggcacacagatgatgaaatgacaggctacgtggccactaggtggtacagggctcctgagatcatgctga actggatgcattacaaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaagaacattg tttcctggtacagaccatattgatcagttgaagctcattttaagactcgttggaaccccaggggctgagcttttgaagaa aatctcctcagagtctgcaagaaactatattcagtctttgactcagatgccgaagatgaactttgcgaatgtatttattg gtgccaatcccctggctgtcgacttgctggagaagatgcttgtattggactcagataagagaattacagcggcccaagcc cttgcacatgcctactttgctcagtaccacgatcctgatgatgaaccagtggccgatccttatgatcagtcctttgaaag cagggacctccttatagatgagtggaaaagcctgacctatgatgaagtcatcagctttgtgccaccaccccttgaccaag aagagatggagtcctgagcacctggtttctgttctgttgatcccacttcactgtgaggggaaggccttttcacgggaact ctccaaatattattcaagtgcctcttgttgcagagatttcctccatggtggaagggggtgtgcgtgcgtgtgcgtgcgtg ttagtgtgtgtgcatgtgt (SEQ ID NO: 12101) aattaaccctcactaaagggagtcgactcgatccccccgcctcagccccttttttcttttttttttcattttcagttcag gagagttttagcttaattataggctacagaaccagctttgggcttcatctatcctttctaatatttactgtttcctattt ctctaatcctagctctttatttcttccctttactttcactgggcttattttgctatagtggaatgcagagggatgagtat tccaggaaggcacaaaaactgtgccaagtcttggagctagggatgagtgggaaagggacatgttcaaccattttaggcca ttccctccccacctcccagctcccagatatgtgcccctcgcaggaggagcccaggaatgggccaaacacctcacttcttt gctctgagggccaccccagccctcccatcaacagctctagaaacccaatggtccttcctggaaacacggggcctgcatca atcagaggtgtttgaaccatgtccctctgggcctgaggggcagaaggggacacaatatgtaatgtaaggagcccctgtca tcagaaatctgacttaatctgttttcagatattagacttccacataaaagttgacttggaaaaagacttctgctgctaaa caaaagttgaaactgccttggtgataaaatataagcagaccagctttctcttctagctttccctctcatttcccataaga ttttggtcaagttatttaatctctctgcatccgtttcctcttctatgaaatgggcatgataataatggtatatacctcct caaggggggtataacgtgaacagagtccttagcacagcactctgtctctacgggagtgaattttcattgtttttctcttt cctgttggagaaagtaagaagaaaacagcgcctttatggcttcccatggtgaatggctggggcgcgtctgtgtccctgtc tcctctctggctccttgtggcctgaacagccagaaggaagccatgccatgctgtttcagccctcagcttccctcttgcat ttcctagaaaagtctttggtgcccagctccagctcagcagattcaggatcccccttcatcatgacttggtcaacgccctg ctcaggccaaggtcctctgagagttccaagcttctccactccctataaaaggccggcggaacagccagaggagcagagag gcaaagaaacattgtgaaatctccaactcttaaccttcaacatgaaagtctctgcagtgcttctgtgcctgctgctcatg acagcagctttcaacccccagggacttgctcagccaggtaagtcacctcccttcgactctccctctctttccctctgttt ctctattcaaggaagacctaagcccgagtgctcctccactttttttttagattgagtctcattatgttgcccaggctgaa gtgcaggggtgcgatcttggctcattgcaaccttcacctcccaggttcaagcgattctcttgcctcagccttctgagtag ctgtgattacaggcaccgccatcacgtgcagctaatttttgtatttttagtagagaaggggtttcactatgttggccagg ctggtctcaaactcttgacctcaagtgatcctcccgtctcggcctcccaaagtgctgggattacaggcgtgagcaccagg cccagccaagtgccccacttctaagcccaccagaatagtaaggctcctcagaggttcactttaacatctaattttaaaga tagaaagctgaagcccatgttggaggcagaagggaccctagccatccacctccaggttattgcagagcaagaatgaaacc taagcttctgactccagatttagggccttttctttgacctcatctgatcgtcccaaactctgcagatctggaccacaccc agaccttcccactggccttgcccgtggcctcccctagatggctgtgacatgtctccaccatgcagctgagcctttgagah cctgaggcacatgtcacaggtcccacctcacctcagggtctagggtgggagtgctgggcttgggggtgagtaagatctac ttcttcctctttgctttgcatcccatacagatgctccctgctgtattcaagctgagaaaagcctaacacatcctcaaagt ctttttctttgtaactatttctagatgcactcaacgtcccatctacttgctgcttcacatttagcagtaagaagatctcc ttgcagaggctgaagagctatgtgatcaccaccagcaggtgtccccagaaggctgtcatgtgggtagaaaaatccctgct cgcctggctcctccccactcccacattccccaatccaaagttctgccccaggagacagacgtcagactgacttgagatct taggatgagatctagccagactgtgtgatgcaaaatcctccaattttggctgcacaacaggtccaaagaggacctataat ttcccacaccttgtttcctggatgggcaccagcccacaccctttagcagatgccaggatcagtttcccaggggcagcaag agcagtggctgcctccagagaccccttctgtccacacacctcctacttcctgtcctggaggggtgccccttcacctgtag taggtggaccaggcaggtttagaacccagtgtgtcatctcctaggtaaaccctcaaagggttccatctaactgtgccaga tctccttcctccacagcttcagaaccaaactgggcaaggagatctgtgctgacccaaaggagaagtgggtccagaattat atgaaacacctgggccggaaagctcacaccctgaagacttgaactctgctacccctactgaaatcaagctggagtacgtg aaatgacttttccattctcctctggcctcctcttctatgctttggaatacttctaccataattttcaaataggatgcatt cggttttgtgattcaaaatgtactatgtgttaagtaatattggctattatttgacttgttgctggtttggagtttatttg agtattgctgatcttttctaaagcaaggccttgagcaagtaggttgctgtctctaagcccccttcccttccactatgagc tgctggcagtgggtttgtattcggttcccaggggttgagc (SEQ ID NO: 12102) ggcaaagaaacattgtgaaatctccaactcttaaccttcaacatgaaagtctctgcagtgcttctgtgcctgctgctcat gacagcagctttcaacccccagggacttgctcagccagatgcactcaacgtcccatctacttgctgcttcacatttagca gtaagaagatctccttgcagaggctgaagagctatgtgatcaccaccagcaggtgtccccagaaggctgtcatcttcaga accaaactgggcaaggagatctgtgctgacccaaaggagaagtgggtccagaattatatgaaacacctgggccggaaagc tcacaccctgaagacttgaactctgctacccctactgaaatcaagctggagtacgtgaaatgacttttccattctcctct ggcctcctcttctatgctttggaatacttctaccataattttcaaataggatgcattc'ggttttgtgattcaaaatgtac tatgtgttaagtaatattggctattatttgacttgttgctggtttggagtttatttgagtattgctgatcttttctatag caaggccttgagcaagtaggttgctgtctctaagcccccttcccttccactatgagctgctggcagtgggtttgtattcg gttcccaggggttgagagcatgcctgtgggagtcatggacatgaagggatgccgcaatgtaggaaggagagctctttgtg aatgtgaggtgttgctaaatatgttattgtggaaagatgaatgcaatagtaggactgctgacattttgcagaaaatacat tttatttaaaaatctcctaaaaaaaaaaaaaaaaaaaaaaaagaaaaaaaaaaaa (SEQ ID NO.-12103) acattgtgaaatctccaactcttaaccttcaacatgaaagtctctgcagtgcttctgtgcctgctgctcatgacagcagc tttcaacccccagggacttgctcagccagatgcactcaacgtcccatctacttgctgcttcacatttagcagtaagaaga tctccttgcagaggctgaagagctatgtgatcaccaccagcaggtgtccccagaaggctgtcatcttcagaaccaaactg ggcaaggagatctgtgctgacccaaaggagaagtgggtccagaattatatgaaacacctgggccggaaagctcacaccct gaagacttgaactctgctacccctactgaaatcaagctggagtacgtgaaatgacttttccattctcctctggcctcctc ttctatgctttggaatacttctaccataattttcaaataggatgcattcggttttgtgattcaaaatgtactatgtgtta agtaatattggctattatttgacttgttgctggtttggagtttatttgagtattgctgatcttttctaaagcaaggcctt gagcaagtaggttgctgtctctaagcccccttcccttccactatgagctgctggcagtgggttgtattcggttcccaggg gttgagagcatgcctgtgggagtcatggacatgaagggatgctgcaatgtaggaaggagagctctttgtgaatgtgaggt tgttgctaaattattgtttattgtggaaagatgaatgcaatagtaggactgctgacattttgcagaaaatacattttatt taaaatctcctaaaaaaaaaaaaaa (SEQ ID NO: 12104) aaaaggccggcggaacagccagaggagcagagaggcaaagaaacattgtgaaatctccaactcttaaccttcaacatgaa agtctctgcagtgcttctgtgcctgctgctcatgacagcagctttcaacccccagggacttgctcagccagatgcactca acgtcccatctacttgctgcttcacatttagcagtaagaagatctccttgcagaggctgaagagctatgtgatcaccacc agcaggtgtccccagaaggctgtcatcttcagaaccaaactgggcaaggagatctgtgctgacccaaaggagaagtgggt ccagaattatatgaaacacctgggccggaaagctcacaccctgaagacttgaactctgctacccctactgaaatcaagct ggagtacgtgaaatgacttttccattctcctctggcctcctcttctatgctttggaatacttctaccataattttcaaat aggatgcattcggttttgtgattcaaaatgtactatgtgttaagtaatattggctattatttgacttgttgctggtttgg agtttatttgagtattgctgatcttttctaaagcaaggccttgagcaagtaggttgctgtctctaagcccccttcccttc cactatgagctgctggcagtgggtttgtattcggttcccaggggttgagagcatgcctgtgggagtcatggacatgaagg gatgctgcaatgtaggaaggagagctctttgtgaatgtgaggtgttgctaaatatgttattgtggaaagatgaatgcaat agtaggactgctgacattttgcagaaaatacattttatttaaaatctccaaaaaaaaaaa (SEQ ID NO-.12105) aattaaccctcactaaagggagtcgactcgatccccccgcctcagccccttttttcttttttttttcattttcagttcag gagagttttagcttaattataggctacagaaccagctttgggcttcatctatcctttctaatatttactgtttcctattt ctctaatcctagctcttta tcttccctttactttcactgggcttattttgctatagtggaatgcagagggatgagtat tccaggaaggcacaaaaactgtgccaagtcttggagctagggatgagtgggaaagggacatgttcaaccattttaggcca ttccctccccacctcccagctcccagatatgtgcccctcgcaggaggagcccaggaatgggccaaacacctcacttcttt gctctgagggccaccccagccctcccatcaacagctctagaaacccaatggtccttcctggaaacacggggcctgcatca atcagaggtgtttgaaccatgtccctctgggcctgaggggcagaaggggacacaatatgtaatgtaaggagcccctgtca tcagaaatctgacttaatctgttttcagatattagacttccacataaaagttgacttggaaaaagacttctgctgctaaa caaaagttgaaactgccttggtgataaaatataagcagaccagctttctcttctagctttccctctcatttcccataaga ttttggtcaagttatttaatctctctgcatccgtttcctcttctatgaaatgggcatgataataatggtatatacctcct caaggggggtataacgtgaacagagtccttagcacagcactctgtctctacgggagtgaattttcattgtttttctcttt cctgttggagaaagtaagaagaaaacagcgcctttatggcttcccatggtgaatggctggggcgcgtctgtgtccctgtc tcctctctggctccttgtggcctgaacagccagaaggaagccatgccatgctgtttcagccctcagcttccctcttgcat ttcctagaaaagtctttggtgcccagctccagctcagcagattcaggatcccccttcatcatgacttggtcaacgccctg ctcaggccaaggtcctctgagagttccaagcttctccactccctataaaaggccggcggaacagccagaggagcagagag gcaaagaaacattgtgaaatctσcaactcttaaccttcaacatgaaagtctctgcagtgcttctgtgcctgctgctcatg acagcagctttcaacccccagggacttgctcagccaggtaagtcacctcccttcgactctccctctctttccctctgttt ctctattcaaggaagacctaagcccgagtgctcctccactttttttttagattgagtctcattatgttgcccaggctgaa gtgcaggggtgcgatcttggctcattgcaaccttcacctcccaggttcaagcgattctcttgcctcagccttctgagtag ctgtgattacaggcaccgccatcacgtgcagctaatttttgtatttttagtagagaaggggtttcactatgttggccagg ctggtctcaaactcttgacctcaagtgatcctcccgtctcggcctcccaaagtgctgggattacaggcgtgagcaccagg cccagccaagtgccccacttctaagcccaccagaatagtaaggctcctcagaggttcactttaacatctaattttaaaga tagaaagctgaagcccatgttggaggcagaagggaccctagccatccacctccaggttattgcagagcaagaatgaaacc taagcttctgactccagatttagggccttttctttgacctcatctgatcgtcccaaactctgcagatctggaccacaccc agaccttcccactggccttgcccgtggcctcccctagatggctgtgacatgtctccaccatgcagctgagcctttgagab. cctgaggcacatgtcacaggtcccacctcacctcagggtctagggtgggagtgctgggcttgggggtgagtaagatctac ttcttcctctttgctttgcatcccatacagatgctccctgctgtattcaagctgagaaaagcctaacacatcctcaaagt ctttttctttgtaactatttctagatgcactcaacgtcccatctacttgctgcttcacatttagcagtaagaagatctcc ttgcagaggctgaagagctatgtgatcaccaccagcaggtgtccccagaaggctgtcatgtgggtagaaaaatccctgct cgcctggctcctccccactcccacattccccaatccaaagttctgccccaggagacagacgtcagactgacttgagatct taggatgagatctagccagactgtgtgatgcaaaatcctccaattttggctgcacaacaggtccaaagaggacctataat ttcccacaccttgtttcctggatgggcaccagcccacaccctttagcagatgccaggatcagtttcccaggggcagcaag agcagtggctgcctccagagaccccttctgtccacacacctcctacttcctgtcctggaggggtgccccttcacctgtag taggtggaccaggcaggtttagaacccagtgtgtcatctcctaggtaaaccctcaaagggttccatctaactgtgccaga tctccttcctccacagcttcagaaccaaactgggcaaggagatctgtgctgacccaaaggagaagtgggtccagaattat atgaaacacctgggccggaaagctcacaccctgaagacttgaactctgctacccctactgaaatcaagctggagtacgtg aaatgacttttccattctcctctggcctcctcttctatgctttggaatacttctaccataattttcaaataggatgcatt cggttttgtgattcaaaatgtactatgtgttaagtaatattggctattatttgacttgttgctggtttggagtttatttg agtattgctgatcttttctaaagcaaggccttgagcaagtaggttgctgtctctaagcccccttcccttccactatgagc tgctggcagtgggtttgtattcggttcccaggggttgagcggcaaagaaacattgtgaaatctccaactcttaaccttca acatgaaagtctctgcagtgcttctgtgcctgctgctcatgacagcagctttcaacccccagggacttgctcagccagat gcactcaacgtcccatctacttgctgcttcacatttagcagtaagaagatctccttgcagaggctgaagagctatgtgat caccaccagcaggtgtccccagaaggctgtcatcttcagaaccaaactgggcaaggagatctgtgctgacccaaaggaga agtgggtccagaattatatgaaacacctgggccggaaagctcacaccctgaagacttgaactctgctacccctactgaaa tcaagctggagtacgtgaaatgacttttccattctcctctggcctcctcttctatgctttggaatacttctaccataatt ttcaaataggatgcattcggttttgtgattcaaaatgtactatgtgttaagtaatattggctattatttgacttgttgct ggtttggagtttatttgagtattgctgatcttttctatagcaaggccttgagcaagtaggttgctgtctctaagccccct tcccttccactatgagctgctggcagtgggtttgtattcggttcccaggggttgagagcatgcctgtgggagtcatggac atgaagggatgccgcaatgtaggaaggagagctctttgtgaatgtgaggtgttgctaaatatgttattgtggaaagatga atgcaatagtaggactgctgacattttgcagaaaatacattttatttaaaaatctcctaaaaaaaaaaaaaaaaaaaaaa aagaaaaaaaaaaaaacattgtgaaatctccaactcttaaccttcaacatgaaagtctctgcagtgcttctgtgcctgct gctcatgacagcagctttcaacccccagggacttgctcagccagatgcactcaacgtcccatctacttgctgcttcacat ttagcagtaagaagatctccttgcagaggctgaagagctatgtgatcaccaccagcaggtgtccccagaaggctgtcatc ttcagaaccaaactgggcaaggagatctgtgctgacccaaaggagaagtgggtccagaattatatgaaacacctgggccg gaaagctcacaccctgaagacttgaactctgctacccctactgaaatcaagctggagtacgtgaaatgacttttccattc tcctctggcctcctcttctatgctttggaatacttctaccataattttcaaataggatgcattcggttttgtgattcaaa atgtactatgtgttaagtaatattggctattatttgacttgttgctggtttggagtttatttgagtattgctgatctttt ctaaagcaaggccttgagcaagtaggttgctgtctctaagcccccttcccttccactatgagctgctggcagtgggttgt attcggttcccaggggttgagagcatgcctgtgggagtcatggacatgaagggatgctgcaatgtaggaaggagagctct ttgtgaatgtgaggttgttgctaaattattgtttattgtggaaagatgaatgcaatagtaggactgctgacattttgcag aaaatacattttatttaaaatctcctaaaaaaaaaaaaaaaaaaggccggcggaacagccagaggagcagagaggcaaag aaacattgtgaaatctccaactcttaaccttcaacatgaaagtctctgcagtgcttctgtgcctgctgctcatgacagca gctttcaacccccagggacttgctcagccagatgcactcaacgtcccatctacttgctgcttcacatttagcagtaagaa gatctccttgcagaggctgaagagctatgtgatcaccaccagcaggtgtccccagaaggctgtcatcttcagaaccaaac tgggcaaggagatctgtgctgacccaaaggagaagtgggtccagaattatatgaaacacctgggccggaaagctcacacc ctgaagacttgaactctgctacccctactgaaatcaagctggagtacgtgaaatgacttttccattctcctctggcctcc tcttctatgctttggaatacttctaccataattttcaaataggatgcattcggttttgtgattcaaaatgtactatgtgt taagtaatattggctattatttgacttgttgctggtttggagtttatttgagtattgctgatcttttctaaagcaaggcc ttgagcaagtaggttgctgtctctaagcccccttcccttccactatgagctgctggcagtgggtttgtattcggttccca ggggttgagagcatgcctgtgggagtcatggacatgaagggatgctgcaatgtaggaaggagagctctttgtgaatgtga ggtgttgctaaatatgttattgtggaaagatgaatgcaatagtaggactgctgacattttgcagaaaatacattttattt aaaatctccaaaaaaaaaaa (SEQ ID NO: 12106) cgcccgggcaggtcctctgcctagcactgctcccccaaggctcccagaaatctcaggtcagaggcacggacagcctctgg agctctcgtctggtgggaccatgaactgccagcagctgtggctgggcttcctactccccatgacagtctcaggccgggtc ctggggcttgcagaggtggcgcccgtggactacctgtcacaatatgggtacctacagaagcctctagaaggatctaataa cttcaagccagaagatatcaccgaggctctgagagcttttcaggaagcatctgaacttccagtctcaggtcagctggatg atgccacaagggcccgcatgaggcagcctcgttgtggcctagaggatcccttcaaccagaagacccttaaatacctgttg ctgggccgctggagaaagaagcacctgactttccgcatcttgaacctgccctccacccttccaccccacacagcccgggc agccctgcgtcaagccttccaggactggagcaatgtggctcccttgaccttccaagaggtgcaggctggtgcggctgaca tccgcctctccttccatggccgccaaagctcgtactgttccaatacttttgatgggcctgggagagtcctggcccatgcc gacatcccagagctgggcagtgtgcacttcgacgaagacgagttctggactgaggggacctaccgtggggtgaacctgcg catcattgcagcccatgaagtgggccatgctctggggcttgggcactcccgatattcccaggccctcatggccccagtct acgagggctaccggccccactttaagctgcacccagatgatgtggcagggatccaggctctctatggcaagaagagtcca gtgataagggatgaggaagaagaagagacagagctgcccactgtgcccccagtgcccacagaacccagtcccatgccaga cccttgcagtagtgaactggatgccatgatgctggggccccgtgggaagacctatgctttcaagggggactatgtgtgga ctgtatcagattcaggaccgggccccttgttccgagtgtctgccctttgggaggggctccccggaaacctggatgctgct gtctactcgcctcgaacacaatggattcacttctttaagggagacaaggtgtggcgctacattaatttcaagatgtctcc tggcttccccaagaagctgaataggtcagaacctaacctggatgcagctctctattggcctctcaaccaaaaggtgttcc tctttaagggctccgggtactggcagtgggacgagctagcccgaactgacttcagcagctaccccaaaccaatcaagggt ttgtttacgggagtgccaaaccagccctcggctgctatgagttggcaagatggccgagtctacttcttcaagggcaaagt ctactggcgcctcaaccagcagcttcgagtagagaaaggctatcccagaaatatttcccacaactggatgcactgtcgtc cccggactatagacactaccccatcaggtgggaataccactccctcaggtacgggcataaccttggataccactctctca gccacagaaaccacgtttgaatactgactgctcacccacagacacaatcttggacattaacccctgaggctccaccaccc accctttcatttcccccccagaagcctaaggcctaatagctgaatgaaatacctgtctgctcagtagaaccttgcaggtg ctgtagcaggcgcaagaccgtagatctcaggcctctaacacttccaactccagccaccactttcctgtgcattttcactc ctgagaagtgctcccctaactcagatcccctaacttagatttggcccccaactccatttcctgtctgtcttagacagccc ttccaactgtgtcatctcttctctggaggtcaatggtggagggagatgcctgggtcctgttcttcctacataaaatgcaa gaaaacagcatggccagtaaactgagcaagggccttggaatccttgagaatcacatttatgtgcttatgattacgggcaa gctaattaaccttgttgaatctcagattccccatttgcaacattaggttaagaccagtactgcaggattgttgcactaaa tgaaatactgtatgtgaagtgcctggcacagtgtctggtacatttgtgtttaataaaagctaactccatgttcataagaa aaaaaaaa (SEQ ID NO: 12107) ggagaccggccgcatggacccagggacagtggccaccatgcgtaagccccgctgctccctgcctgacgtgctgggggtgg cggggctggtcaggcggcgtcgccggtacgctctgagcggcagcgtgtggaagaagcgaaccctgacatggagggtacgt tccttcccccagagctcccagctgagccaggagaccgtgcgggtcctcatgagctatgccctgatggcctggggcatgga gtcaggcctcacatttcatgaggtggattccccccagggccaggagcccgacatcctcatcgactttgcccgcgccttcc accaggacagctaccccttcgacgggttggggggcaccctagcccatgccttcttccctggggagcaccccatctccggg gacactcactttgacgatgaggagacctggacttttgggtcaaaagcctctcagcagctggagcaggagctggcaggcgg ctcaccggttgatgaggagctgggcttcagccggggctggcgtgtgaatcctctgggtcctggcagtcctgagcgcctga gctgaatacagagggaagaggctgggagcaaggccgggtgctggggccggcaggctgtgttctgaga (SEQ ID NO: 12108) atgatcttactcacattcagcactggaagacggttggatttcgtgcatcattcgggggtgtttttcttgcaaaccttgct ttggattttatgtgctacagtctgcggaacggagcagtatttcaatgtggaggtttggttacaaaagtacggctaccttc caccgactgaccccagaatgtcagtgctgcgctctgcagagaccatgcagtctgccctagctgccatgcagcagttctat ggcattaacatgacaggaaaagtggacagaaacacaattgactggatgaagaagccccgatgcggtgtacctgaccagac aagaggtagctccaaatttcatattcgtcgaaagcgatatgcattgacaggacagaaatggcagcacaagcacatcactt acagtataaagaacgtaactccaaaagtaggagaccctgagactcgtaaagctattcgccgtgcctttgatgtgtggcag aatgtaactcctctgacatttgaagaagttccctacagtgaattagaaaatggcaaacgtgatgtggatataaccattat ttttgcatctggtttccatggggacagctctccctttgatggagagggaggatttttggcacatgcctacttccctggac caggaattggaggagatacccattttgactcagatgagccatggacactaggaaatcctaatcatgatggaaatgactta tttcttgtagcagtccatgaactgggacatgctctgggattggagcattccaatgaccccactgccatcatggctccatt ttaccagtacatggaaacagacaacttcaaactacctaatgatgatttacagggcatccagaagatatatggtccacctg acaagattcctccacctacaagacctctaccgacagtgcccccacaccgctctattcctccggctgacccaaggaaaaat gacaggccaaaacctcctcggcctccaaccggcagaccctcctatcccggagccaaacccaacatctgtgatgggaactt taacactctagctattcttcgtcgtgagatgtttgttttcaaggaccagtggttttggcgagtgagaaacaacagggtga tggatggatacccaatgcaaattacttacttctggcggggcttgcctcctagtatcgatgcagtttatgaaaatagcgac gggaattttgtgttctttaaagtgaagggagacactctatctgtaatccaagatggttggctctacaaataccattggaa atggattctagaacaaaggcagtcagtgcctgtgctctcaagacaaactgaaaagcacaagacctatgaagaattatctt ccatcacatactaacaaagaacaatcaggaattgaaaatttaaaataaaaggccatttacaattgcattcgaaaacacca aataccgagggatcaatctgcaaaaaatgtgcatgacctctacattgaaaacaacaaaacactactaaatgtttgtcttt aaaggcagctgg (SEQ ID NO: 12109) tagaagtttacaatgaagtttcttctaatactgctcctgcaggccactgcttctggagctcttcccctgaacagctctac aagcctggaaaaaaataatgtgctatttggtgagagatacttagaaaaattttatggccttgagataaacaaacttccag tgacaaaaatgaaatatagtggaaacttaatgaaggaaaaaatccaagaaatgcagcacttcttgggtctgaaagtgacc gggcaactggacacatctaccctggagatgatgcacgcacctcgatgtggagtccccgatctccatcatttcagggaaat gccaggggggcccgtatggaggaaacattatatcacctacagaatcaataattacacacctgacatgaaccgtgaggatg ttgactacgcaatccggaaagctttccaagtatggagtaatgttacccccttgaaattcagcaagattaacacaggcatg gctgacattttggtggtttttgcccgtggagctcatggagacttccatgcttttgatggcaaaggtggaatcctagccca tgcttttggacctggatctggcattggaggggatgcacatttcgatgaggacgaattctggactacacattcaggaggca caaacttgttcctcactgctgttcacgagattggccattccttaggtcttggccattctagtgatccaaaggctgtaatg ttccccacctacaaatatgtcgacatcaacacatttcgcctctctgctgatgacatacgtggcattcagtccctgtatgg agacccaaaagagaaccaacgcttgccaaatcctgacaattcagaaccagctctctgtgaccccaatttgagttttgatg ctgtcactaccgtgggaaataagatctttttcttcaaagacaggttcttctggctgaaggtttctgagagaccaaagacc agtgttaatttaatttcttccttatggccaaccttgccatctggcattgaagctgcttatgaaattgaagccagaaatca agtttttctttttaaagatgacaaatactggttaattagcaatttaagaccagagccaaattatcccaagagcatacatt cttttggttttcctaactttgtgaaaaaaattgatgcagctgtttttaacccacgtttttataggacctacttctttgta gataaccagtattggaggtatgatgaaaggagacagatgatggaccctggttatcccaaactgattaccaagaacttcca aggaatcgggcctaaaattgatgcagtcttctattctaaaaacaaatactactatttcttccaaggatctaaccaatttg aatatgacttcctactccaacgtatcaccaaaacactgaaaagcaatagctggtttggttgttagaaatggtgtaattaa tggtttttgttagttcacttcagcttaataagtatttattgcatatttgctatgtcctcagtgtaccactacttagagat atgtatcataaaaataaaatctgtaaaccataggtaatgattatataaaatacataatatttttcaattttgaaaactct aattgtccattcttgcttgactctactattaagtttgaaaatagttaccttcaaagcaagataattctatttgaagcatg ctctgtaagttgcttcctaacatccttggactgagaaattatacttacttctggcataactaaaattaagtatatatatt ttggctcaaataaaattg (SEQ ID NO: 12110) aaagaaggtaagggcagtgagaatgatgcatcttgcattccttgtgctgttgtgtctgccagtctgctctgcctatcctc tgagtggggcagcaaaagaggaggactccaacaaggatcttgcccagcaatacctagaaaagtactacaacctcgaaaag gatgtgaaacagtttagaagaaaggacagtaatctcattgttaaaaaaatccaaggaatgcagaagttccttgggttgga ggtgacagggaagctagacactgacactctggaggtgatgcgcaagcccaggtgtggagttcctgacgttggtcacttca gctcctttcctggcatgccgaagtggaggaaaacccaccttacatacaggattgtgaattatacaccagatttgccaaga gatgctgttgattctgccattgagaaagctctgaaagtctgggaagaggtgactccactcacattctccaggctgtatga aggagaggctgatataatgatctctttcgcagttaaagaacatggagacttttactcttttgatggcccaggacacagtt tggctcatgcctacccacctggacctgggctttatggagatattcactttgatgatgatgaaaaatggacagaagatgca tcaggcaccaatttat cctcgttgctgctcatgaacttggccactccctggggctctttcactcagccaacactgaagc tttgatgtacccactctacaactcattcacagagctcgcccagttccgcctttcgcaagatgatgtgaatggcattcagt ctctctacggacctccccctgcctctactgaggaacccctggtgcccacaaaatctgttccttcgggatctgagatgcca gccaagtgtgatcctgctttgtccttcgatgccatcagcactctgaggggagaatatctgttctttaaagacagatattt ttggcgaagatcccactggaaccctgaacctgaatttcatttgatttctgcattttggccctctcttccatcatatttgg atgctgcatatgaagttaacagcagggacaccgtttttatttttaaaggaaatgagttctgggccatcagaggaaatgag gtacaagcaggttatccaagaggcatccataccctgggttttcctccaaccataaggaaaattgatgcagctgtttctga caaggaaaagaagaaaacatacttctttgcagcggacaaatactggagatttgatgaaaatagccagtccatggagcaag gcttccctagactaatagctgatgactttccaggagttgagcctaaggttgatgctgtattacaggcatttggatttttc tacttcttcagtggatcatcacagtttgagtttgaccccaatgccaggatggtgacacacatattaaagagtaacagctg gttacattgctaggcgagatagggggaagacagatatgggtgtttttaataaatctaataattattcatctaatgtatta tgagccaaaatggttaatttttcctgcatgttctgtgactgaagaagatgagccttgcagatatctgcatgtgtcatgaa gaatgtttctggaattcttcacttgcttttgaattgcactgaacagaattaagaaatactcatgtgcaataggtgagaga atgtattttcatagatgtgttattacttcctcaataaaaagttttattttgggcctgttcctt (SEQ ID NO: 12111) ctgaggtgggtaagagtacaatggctaaatcttaacacactcttacgtgtacaccctaccgtacaccatccagactcgtc cccatacaatcaggagtgatcagtacgtaaatgcttatggtgtgatttgaaggggtgttagagtagatcatctctcacac cgcagcagcactgcttccaattcatcctttggaattttattccctgactgttaaaagtttttagtgcttaaatattctct attgaggtaagagacagattctgtgcaatgggacaattaggtcaagagggaaagaagctgaggtgataggcagatagatt ccagaggcaaacttttcccatctgctaaagttgaaaagagtaacccacatcctaccaacgctagacaatctaggatgtag ggaaagtttgtctctggaatctatccaggtacccagttgggactgagcttcagcttagatgtctgaagatgttaagttat agaatcaggtttaagtctgaagatgttaagttatagaatcaggatctgagccggtacaacacgtggataaacaatgaagt cgatgttacaaatttttttttgctacttgtaaaatctctgtatcacatttctctagggagctggattccgtttaggagca ctcatttactccaggaaaaggattttatttaatctttcaacatttactttaaaaactttttttatctataatgaatataa ggaagtattataatgaaaaccaagttatcaggctttaagaaaatatattttaagttctccttctcttttagttgcttgat a ttcttttacaagggcttattttgtagataggtggacgtagaggcttatttatcattttgaaggtacatactctgaatt gcttgagtgatggactagatgctaattgatccattgtcgtctgaataaagtcatgcttttgtttgcatgtttttagagat agtcaagggatgatatcaactatgagtcactcataggattcatattcacagaacccggactaagggctatataaagagga acagttcaggaacttaggctagaaaggacacagtaaactgaattgatccgtttagaagtttacaatgaagtttcttctaa tactgctcctgcaggccactgcttctggagctcttcccctgaacagctctacaagcctggaaaaaaataatgtgctattg ggtgagaga (SEQ ID NO: 12112) cgcccgggcaggtcctctgcctagcactgctcccccaaggctcccagaaatctcaggtcagaggcacggacagcctctgg agctctcgtctggtgggaccatgaactgccagcagctgtggctgggcttcctactccccatgacagtctcaggccgggtc ctggggcttgcagaggtggcgcccgtggactacctgtcacaatatgggtacctacagaagcctctagaaggatctaataa cttcaagccagaagatatcaccgaggctctgagagcttttcaggaagcatctgaacttccagtctcaggtcagctggatg atgccacaagggcccgcatgaggcagcctcgttgtggcctagaggatcccttcaaccagaagacccttaaatacctgttg ctgggccgctggagaaagaagcacctgactttccgcatcttgaacctgccctccacccttccaccccacacagcccgggc agccctgcgtcaagccttccaggactggagcaatgtggctcccttgaccttccaagaggtgcaggctggtgcggctgaca tccgcctctccttccatggccgccaaagctcgtactgttccaatacttttgatgggcctgggagagtcctggcccatgcc gacatcccagagctgggcagtgtgcacttcgacgaagacgagttctggactgaggggacctaccgtggggtgaacctgcg catcattgcagcccatgaagtgggccatgctctggggcttgggcactcccgatattcccaggccctcatggccccagtct acgagggctaccggccccactttaagctgcacccagatgatgtggcagggatccaggctctctatggcaagaagagtcca gtgataagggatgaggaagaagaagagacagagctgcccactgtgcccccagtgcccacagaacccagtcccatgccaga cccttgcagtagtgaactggatgccatgatgctggggccccgtgggaagacctatgctttcaagggggactatgtgtgga ctgtatcagattcaggaccgggccccttgttccgagtgtctgccctttgggaggggctccccggaaacctggatgctgct gtctactcgcctcgaacacaatggattcacttctttaagggagacaaggtgtggcgctacattaatttcaagatgtctcc tggcttccccaagaagctgaataggtcagaacctaacctggatgcagctctctattggcctctcaaccaaaaggtgttcc tctttaagggctccgggtactggcagtgggacgagctagcccgaactgacttcagcagctaccccaaaccaatcaagggt ttgtttacgggagtgccaaaccagccctcggctgctatgagttggcaagatggccgagtctacttcttcaagggcaaagt ctactggcgcctcaaccagcagcttcgagtagagaaaggctatcccagaaatatttcccacaactggatgcactgtcgtc cccggactatagacactaccccatcaggtgggaataccactccctcaggtacgggcataaccttggataccactctctca gccacagaaaccacgtttgaatactgactgctcacccacagacacaatcttggacattaacccctgaggctccaccaccc accctttcatttcccccccagaagcctaaggcctaatagctgaatgaaatacctgtctgctcagtagaaccttgcaggtg ctgtagcaggcgcaagaccgtagatctcaggcctctaacacttccaactccagccaccactttcctgtgcattttcactc ctgagaagtgctcccctaactcagatcccctaacttagatttggcccccaactccatttcctgtctgtcttagacagccc ttccaactgtgtcatctcttctctggaggtcaatggtggagggagatgcctgggtcctgttcttcctacataaaatgcaa gaaaacagcatggccagtaaactgagcaagggccttggaatccttgagaatcacatttatgtgcttatgattacgggcaa gctaattaaccttgttgaatctcagattccccatttgcaacattaggttaagaccagtactgcaggattgttgcactaaa tgaaatactgtatgtgaagtgcctggcacagtgtctggtacatttgtgtttaataaaagctaactccatgttcataagaa aaaaaaaaggagaccggccgcatggacccagggacagtggccaccatgcgtaagccccgctgctccctgcctgacgtgct gggggtggcggggctggtcaggcggcgtcgccggtacgctctgagcggcagcgtgtggaagaagcgaaccctgacatgga gggtacgttccttcccccagagctcccagctgagccaggagaccgtgcgggtcctcatgagctatgccctgatggcctgg ggcatggagtcaggcctcacatttcatgaggtggattccccccagggccaggagcccgacatcctcatcgactttgcccg cgccttccaccaggacagctaccccttcgacgggttggggggcaccctagcccatgccttcttccctggggagcacccca tctccggggacactcactttgacgatgaggagacctggacttttgggtcaaaagcctctcagcagctggagcaggagctg gcaggcggctcaccggttgatgaggagctgggctt^'cagccggggctggcgtgtgaatcctctgggtcctggcagtcctga gcgcctgagctgaatacagagggaagaggctgggagcaaggccgggtgctggggccggcaggctgtgttctgagaatgat cttactcacattcagcactggaagacggttggatttcgtgcatcattcgggggtgtttttcttgcaaaccttgctttgga ttttatgtgctacagtctgcggaacggagcagtatttcaatgtggaggtttggttacaaaagtacggctaccttccaccg actgaccccagaatgtcagtgctgcgctctgcagagaccatgcagtctgccctagctgccatgcagcagttctatggcat taacatgacaggaaaagtggacagaaacacaattgactggatgaagaagccccgatgcggtgtacctgaccagacaagag gtagctccaaatttcatattcgtcgaaagcgatatgcattgacaggacagaaatggcagcacaagcacatcacttacagt ataaagaacgtaactccaaaagtaggagaccctgagactcgtaaagctattcgccgtgcctttgatgtgtggcagaatgt aactcctctgacatttgaagaagttccctacagtgaattagaaaatggcaaacgtgatgtggatataaccattatttttg catctggtttccatggggacagctctccctttgatggagagggaggatttttggcacatgcctacttccctggaccagga attggaggagatacccattttgactcagatgagccatggacactaggaaatcctaatcatgatggaaatgacttatttct tgtagcagtccatgaactgggacatgctctgggattggagcattccaatgaccccactgccatcatggctccattttacc agtacatggaaacagacaacttcaaactacctaatgatgatttacagggcatccagaagatatatggtccacctgacaag attcctccacctacaagacctctaccgacagtgcccccacaccgctctattcctccggctgacccaaggaaaaatgacag gccaaaacctcctcggcctccaaccggcagaccctcctatcccggagccaaacccaacatctgtgatgggaactttaaca ctctagctattcttcgtcgtgagatgtttgttttcaaggaccagtggttttggcgagtgagaaacaacagggtgatggat ggatacccaatgcaaattacttacttctggcggggcttgcctcctagtatcgatgcagtttatgaaaatagcgacgggaa ttttgtgttctttaaagtgaagggagacactctatctgtaatccaagatggttggctctacaaataccattggaaatgga ttctagaacaaaggcagtcagtgcctgtgctctcaagacaaactgaaaagcacaagacctatgaagaattatcttccatc acatactaacaaagaacaatcaggaattgaaaatttaaaataaaaggccatttacaattgcattcgaaaacaccaaatac cgagggatcaatctgcaaaaaatgtgcatgacctctacattgaaaacaacaaaacactactaaatgtttgtctttaaagg cagctggtagaagtttacaatgaagtttcttctaatactgctcctgcaggccactgcttctggagctcttcccctgaaca gctctacaagcctggaaaaaaataatgtgctatttggtgagagatacttagaaaaattttatggccttgagataaacaaa cttccagtgacaaaaatgaaatatagtggaaacttaatgaaggaaaaaatccaagaaatgcagcacttcttgggtctgaa agtgaccgggcaactggacacatctaccctggagatgatgcacgcacctcgatgtggagtccccgatctccatcatttca gggaaatgccaggggggcccgtatggaggaaacattatatcacctacagaatcaataattacacacctgacatgaaccgt gaggatgttgactacgcaatccggaaagctttccaagtatggagtaatgttacccccttgaaattcagcaagattaacac aggcatggctgacattttggtggtttttgcccgtggagctcatggagacttccatgcttttgatggcaaaggtggaatcc tagcccatgcttttggacctggatctggcattggaggggatgcacatttcgatgaggacgaattctggactacacattca ggaggcacaaacttgttcctcactgctgttcacgagattggccattccttaggtcttggccattctagtgatccaaaggc tgtaatgttccccacctacaaatatgtcgacatcaacacatttcgcctctctgctgatgacatacgtggcattcagtccc tgtatggagacccaaaagagaaccaacgcttgccaaatcctgacaattcagaaccagctctctgtgaccccaatttgagt tttgatgctgtcactaccgtgggaaataagatctttttcttcaaagacaggttcttctggctgaaggtttctgagagacc aaagaccagtgttaatttaatttcttccttatggccaaccttgccatctggcattgaagctgcttatgaaattgaagcca gaaatcaagtttttctttttaaagatgacaaatactggttaattagcaatttaagaccagagccaaattatcccaagagc atacattcttttggttttcctaactttgtgaaaaaaattgatgcagctgtttttaacccacgtttttataggacctactt ctttgtagataaccagtattggaggtatgatgaaaggagacagatgatggaccctggttatcccaaactgattaccaaga acttccaaggaatcgggcctaaaattgatgcagtcttctattctaaaaacaaatactactatttcttccaaggatctaac caatttgaatatgacttcctactccaacgtatcaccaaaacactgaaaagcaatagctggtttggttgttagaaatggtg taattaatggtttttgttagttcacttcagcttaataagtatttattgcatatttgctatgtcctcagtgtaccactact tagagatatgtatcataaaaataaaatctgtaaaccataggtaatgattatataaaatacataatatttttcaattttga aaactctaattgtccattcttgcttgactctactattaagtttgaaaatagttaccttcaaagcaagataattctatttg aagcatgctctgtaagttgcttcctaacatccttggactgagaaattatacttacttctggcataactaaaattaagtat atatattttggctcaaataaaattgaaagaaggtaagggcagtgagaatgatgcatcttgcattccttgtgctgttgtgt ctgccagtctgctctgcctatcctctgagtggggcagcaaaagaggaggactccaacaaggatcttgcccagcaatacct agaaaagtactacaacctcgaaaaggatgtgaaacagtttagaagaaaggacagtaatctcattgttaaaaaaatccaag gaatgcagaagttccttgggttggaggtgacagggaagctagacactgacactctggaggtgatgcgcaagcccaggtgt ggagttcctgacgttggtcacttcagctcctttcctggcatgccgaagtggaggaaaacccaccttacatacaggattgt gaattatacaccagatttgccaagagatgctgttgattctgccattgagaaagctctgaaagtctgggaagaggtgactc cactcacattctccaggctgtatgaaggagaggctgatataatgatctctttcgcagttaaagaacatggagacttttac tcttttgatggcccaggacacagtttggctcatgcctacccacctggacctgggctttatggagatattcactttgatga tgatgaaaaatggacagaagatgcatcaggcaccaatttattcctcgttgctgctcatgaacttggccactccctggggc tctttcactcagccaacactgaagctttgatgtacccactctacaactcattcacagagctcgcccagttccgcctttcg caagatgatgtgaatggcattcagtctctctacggacctccccctgcctctactgaggaacccctggtgcccacaaaatc tgttccttcgggatctgagatgccagccaagtgtgatcctgctttgtccttcgatgccatcagcactctgaggggagaat atctgttctttaaagacagatatttttggcgaagatcccactggaaccctgaacctgaatttcatttgatttctgcattt tggccctctcttccatcatatttggatgctgcatatgaagttaacagcagggacaccgtttttatttttaaaggaaatga gttctgggccatcagaggaaatgaggtacaagcaggttatccaagaggcatccataccctgggttttcctccaaccataa ggaaaattgatgcagctgtttctgacaaggaaaagaagaaaacatacttctttgcagcggacaaatactggagatttgat gaaaatagccagtccatggagcaaggcttccctagactaatagctgatgactttccaggagttgagcctaaggttgatgc tgtattacaggcatttggatttttctacttcttcagtggatcatcacagtttgagtttgaccccaatgccaggatggtga cacacatattaaagagtaacagctggttacattgctaggcgagatagggggaagacagatatgggtgtttttaataaatc taataattattcatctaatgtattatgagccaaaatggttaatttttcctgcatgttctgtgactgaagaagatgagcct tgcagatatctgcatgtgtcatgaagaatgtttctggaattcttcacttgcttttgaattgcactgaacagaattaagaa atactcatgtgcaataggtgagagaatgtattttcatagatgtgttattacttcctcaataaaaagttttattttgggcc tgttccttctgaggtgggtaagagtacaatggctaaatcttaacacactcttacgtgtacaccctaccgtacaccatcca gactcgtccccatacaatcaggagtgatcagtacgtaaatgcttatggtgtgatttgaaggggtgttagagtagatcatc tctcacaccgcagcagcactgcttccaattcatcctttggaattttattccctgactgttaaaagtttttagtgcttaaa tattctctattgaggtaagagacagattctgtgcaatgggacaattaggtcaagagggaaagaagctgaggtgataggca gatagattccagaggcaaacttttcccatctgctaaagttgaaaagagtaacccacatcctaccaacgctagacaatcta ggatgtagggaaagtttgtctctggaatctatccaggtacccagttgggactgagcttcagcttagatgtctgaagatgt taagttatagaatcaggtttaagtctgaagatgttaagttatagaatcaggatctgagccggtacaacacgtggataaac aatgaagtcgatgttacaaatttttttttgctacttgtaaaatctctgtatcacatttctctagggagctggattccgtt taggagcactcatttactccaggaaaaggattttatttaatctttcaacatttactttaaaaactttttttatctataat gaatataaggaagtattataatgaaaaccaagttatcaggctttaagaaaatatattttaagttctccttctcttttagt tgcttgatatttcttttacaagggcttattttgtagataggtggacgtagaggcttatttatcattttgaaggtacatac tctgaattgcttgagtgatggactagatgctaattgatccattgtcgtctgaataaagtcatgcttttgtttgcatgttt ttagagatagtcaagggatgatatcaactatgagtcactcataggattcatattcacagaacccggactaagggctatat aaagaggaacagttcaggaacttaggctagaaaggacacagtaaactgaattgatccgtttagaagtttacaatgaagtt tcttctaatactgctcctgcaggccactgcttctggagctcttcccctgaacagctctacaagcctggaaaaaaataatg tgctattgggtgagaga (SEQ ID NO: 12113) aaggacacgggcagcagacagtggtcagtcctttcttggctctgctgacactcgagcccacattccgtcacctgctcaga atcatgcaggtctccactgctgcccttgctgtcctcctctgcaccatggctctctgcaaccagttctctgcatcacttgc tgctgacacgccgaccgcctgctgcttcagctacacctcccggcagattccacagaatttcatagctgactactttgaga cgagcagccagtgctccaagcccggtgtcatcttcctaaccaagcgaagccggcaggtctgtgctgaccccagtgaggag tgggtccagaaatatgtcagcgacctagagctgagtgcctgaggggtccagaagcttcgaggcccagcgacctcggtggg ccagtggggaggagcaggagcctgagccttgggaaacatgcgtgtgacctccacagctacctcttctatggactggttgt tgccaaacagccacactgtgggactcttcttaacttaaattttaatttatttatactatttagtttttgtaatttatttt cgatttcacagtgtgtttgtgattgtttgctctgagagttcccctgtcccctcccccttccctcacaccgcgtctggtga caaccgagtggctgtcatcagcctgtgtaggcagtcatggcaccaaagccaccagactgacaaatgtgtatcggatgctt ttgttcagggctgtgatcggcctggggaaataataaagcacgctcttttaaaaggt (SEQ ID NO: 12114) acagccttgaccttatgtcatgggttcaacttggacactgaaaacgcaatgaccttccaagagaacgcaaggggcttcgg gcagagcgtggtccagcttcagggatccagggtggtggttggagccccccaggagatagtggctgccaaccaaaggggca gcctctaccagtgcgactacagcacaggctcatgcgagcccatccgcctgcaggtccccgtggaggccgtgaacatgtcc ctgggcctgtccctggcagccaccaccagcccccctcagctgctggcctgtggtcccaccgtgcaccagacttgcagtga gaacacgtatgtgaaagggctctgcttcctgtttggatccaacctacggcagcagccccagaagttcccagaggccctcc gagggtgtcctcaagaggatagtgacattgccttcttgattgatggctctggtagcatcatcccacatgactttcggcgg atgaaggagtttgtctcaactgtgatggagcaattaaaaaagtccaaaaccttgttctctttgatgcagtactctgaaga attccggattcactttaccttcaaagagttccagaacaaccctaacccaagatcactggtgaagccaataacgcagctgc ttgggcggacacacacggccacgggcatccgcaaagtggtacgagagctgtttaacatcaccaacggagcccgaaagaat gcctttaagatcctagttgtcatcacggatggagaaaagtttggcgatcccttgggatatgaggatgtcatccctgaggc agacagagagggagtcattcgctacgtcattggggtgggagatgccttccgcagtgagaaatcccgccaagagcttaata ccatcgcatccaagccgcctcgtgatcacgtgttccaggtgaataactttgaggctctgaagaccattcagaaccagctt cgggagaagatctttgcgatcgagggtactcagacaggaagtagcagctcctttgagcatgagatgtctcaggaaggctt cagcgctgccatcacctctaatggccccttgctgagcactgtggggagctatgactgggctggtggagtctttctatata catcaaaggagaaaagcaccttcatcaacatgaccagagtggattcagacatgaatgatgcttacttgggttatgctgcc gccatcatcttacggaaccgggtgcaaagcctggttctgggggcacctcgatatcagcacatcggcctggtagcgatgtt caggcagaacactggcatgtgggagtccaacgctaatgtcaagggcacccagatcggcgcctacttcggggcctccctct gctccgtggacgtggacagcaacggcagcaccgacctggtcctcatcggggccccccattactacgagcagacccgaggg ggccaggtgtccgtgtgccccttgcccagggggcagagggctcggtggcagtgtgatgctgttctctacggggagcaggg ccaaccctggggccgctttggggcagccctaacagtgctgggggacgtaaatggggacaagctgacggacgtggccattg gggccccaggagaggaggacaaccggggtgctgtttacctgtttcacggaacctcaggatctggcatcagcccctcccat agccagcggatagcaggctccaagctctctcccaggctccagtattttggtcagtcactgagtgggggccaggacctcac aatggatggactggtagacctgactgtaggagcccaggggcacgtgctgctgctcaggtcccagccagtactgagagtca aggcaatcatggagttcaatcccagggaagtggcaaggaatgtatttgagtgtaatgatcaggtggtgaaaggcaaggaa gccggagaggtcagagtctgcctccatgtccagaagagcacacgggatcggctaagagaaggacagatccagagtgttgt gacttatgacctggctctggactccggccgcccacattcccgcgccgtcttcaatgagacaaagaacagcacacgcagac agacacaggtcttggggctgacccagacttgtgagaccctgaaactacagttgccgaattgcatcgaggacccagtgagc cccattgtgctgcgcctgaacttctctctggtgggaacgccattgtctgctttcgggaacctccggccagtgctggcgga ggatgctcagagactcttcacagccttgtttccctttgagaagaattgtggcaatgacaacatctgccaggatgacctca gcatcaccttcagtttcatgagcctggactgcctcgtggtgggtgggccccgggagttcaacgtgacagtgactgtgaga aatgatggtgaggactcctacaggacacaggtcaccttcttcttcccgcttgacctgtcctaccggaaggtgtccacgct ccagaaccagcgctcacagcgatcctggcgcctggcctgtgagtctgcctcctccaccgaagtgtctggggccttgaaga gcaccagctgcagcataaaccaccccatcttcccggaaaactcagaggtcacctttaatatcacgtttgatgtagactct aaggcttcccttggaaacaaactgctcctcaaggccaatgtgaccagtgagaacaacatgcccagaaccaacaaaaccga attccaactggagctgccggtgaaatatgctgtctacatggtggtcaccagccatggggtctccactaaatatctcaact tcacggcctcagagaataccagtcgggtcatgcagcatcaatatcaggtcagcaacctggggcagaggagcctccccatc agcctgg gttcttggtgcccgtccggctgaaccagactgtcatatgggaccgcccccaggtcaccttctccgagaacct ctcgagtacgtgccacaccaaggagcgcttgccctctcactccgactttctggctgagcttcggaaggcccccgtggtga actgctccatcgctgtctgccagagaatccagtgtgacatcccgttctttggcatccaggaagaattcaatgctaccctc aaaggcaacctctcgtttgactggtacatcaagacctcgcataaccacctcctgatcgtgagcacagctgagatcttgtt taacgattccgtgttcaccctgctgccgggacagggggcgtttgtgaggtcccagacggagaccaaagtggagccgttcg aggtccccaaccccctgccgctcatcgtgggcagctctgtcgggggactgctgctcctggccctcatcaccgccgcgctg tacaagctcggcttcttcaagcggcaatacaaggacatgatgagtgaagggggtcccccgggggccgaaccccagtagcg gctccttcccgacagagctgcctctcggtggccagcaggactctgcccagaccacacgtagcccccaggctgctggacac gtcggacagcgaagtatccccgacaggacgggcttgggcttccatttgtgtgtgtgcaagtgtgtatgtgcgtgtgtgcg agtgtgtgcaagtgtctgtgtgcaagtgtgtgcacgtgtcggtgtgcgtgcatgtgcactcgcacgcccatgtgtgagtg tgtgcaagtatgtgagtgtgtccaagtgtgtgtgcgtgtgtccatgtgtgtgcaagtgtgtgcatgtgtgcgagtgtgtg catgtgtgtgctcaggggcgtgtggctcacgtgtgtgactcagatgtctctggcgtgtgggtaggtgacggccagcgtag cctctccggcagaagggaactgcctgggctcccttgtgcgtgggtgaagccgctgctgggttttcctccgggagagggga cggtcaatcctgtgggtgaagacagagggaaacacagcagcttctctccactgaaagaagtgggacttcccgtcgcctgc agcctgcggcctgctggagcctgcgcagcttggatggagactccatgagaagccgtgggtggaaccaggagcctcctcca caccagcgctgatgcccaataaagatgcccactgaggaatgatg (SEQ ID NO: 12115) agcaggaagctcgcgccgccgtcgccgccgccgctcagcttccccgggcgcgtccaggacccgctgcgccaggcgcgccg tccccggacccggcgtgcgtccctacgaggaaagggaccccgccgctcgagccgcctccgccagccccactgcgaggggt cccagagccagccgcgcccgccctcgcccccggccccgcagccttcccgccctgcgcgccatgaacgcccccgagcggca gccccaacccgacggcggggacgccccaggccacgagcctgggggcagcccccaagacgagcttgacttctccatcctct tcgactatgagtatttgaatccgaacgaagaagagccgaatgcacataaggtcgccagcccaccctccggacccgcatac cccgatgatgtaatggactatggcctcaagccatacagcccccttgctagtctctctggcgagccccccggccgattcgg agagccggatagggtagggccgcagaagtttctgagcgcggccaagccagcaggggcctcgggcctgagccctcggatcg agatcactccgtcccacgaactgatccaggcagtggggcccctccgcatgagagacgcgggcctcctggtggagcagcct cccctggccggggtggccgccagcccgaggttcaccctgcccgtgcccggcttcgagggctaccgcgagccgctttgctt gagccccgctagcagcggctcctctgccagcttcatttctgacaccttctccccctacacctcgccctgcgtctcgccca ataacggcgggcccgacgacctgtgtccgcagtttcaaaacatccctgctcattattcccccagaacctcgccaataatg tcacctcgaaccagcctcgccgaggacagctgcctgggccgccactcgcccgtgccccgtccggcctcccgctcctcatc gcctggtgccaagcggaggcattcgtgcgccgaggccttggttgccctgccgcccggagcctcaccccagcgctcccgga gcccctcgccgcagccctcatctcacgtggcaccccaggaccacggctccccggctgggtacccccctgtggctggctct gccgtgatcatggatgccctgaacagcctcgccacggactcgccttgtgggatcccccccaagatgtggaagaccagccc tgacccctcgccggtgtctgccgccccatccaaggccggcctgcctcgccacatctacccggccgtggagttcctggggc cctgcgagcagggcgagaggagaaactcggctccagaatccatcctgctggttccgcccacttggcccaagccgctggtg cctgccattcccatctgcagcatcccagtgactgcatccctccctccacttgagtggccgctgtccagtcagtcaggctc ttacgagctgcggatcgaggtgcagcccaagccacatcaccgggcccactatgagacagaaggcagccgaggggctgtca aagctccaactggaggccaccctgtggttcagctccatggctacatggaaaacaagcctctgggacttcagatcttcatt gggacagctgatgagcggatccttaagccgcacgccttctaccaggtgcaccgaatcacggggaaaactgtcaccaccac cagctatgagaagatagtgggcaacaccaaagtcctggagatccccttggagcccaaaaacaacatgagggcaaccatcg actgtgcggggatcttgaagcttagaaacgccgacattgagctgcggaaaggcgagacggacattggaagaaagaacacg cgggtgagactggttttccgagttcacatcccagagtccagtggcagaatcgtctctttacagactgcatctaaccccat cgagtgctcccagcgatctgctcacgagctgcccatggttgaaagacaagacacagacagctgcctggtctatggcggcc agcaaatgatcctcacggggcagaactttacatccgagtccaaagttgtgtttactgagaagaccacagatggacagcaa atttgggagatggaagccacggtggataaggacaagagccagcccaacatgctttttgttgagatccctgaat tcggaa caagcatatccgcacacctgtaaaagtgaacttctacgtcatcaatgggaagagaaaacgaagtcagcctcagcacttta cctaccacccagtcccagccatcaagacggagcccacggatgaatatgaccccactctgatctgcagccccacccatgga ggcctggggagccagccttactacccccagcacccgatggtggccgagtccccctcctgcctcgtggccaccatggctcc ctgccagcagttccgcacggggctctcatcccctgacgcccgctaccagcaacagaacccagcggccgtactctaccagc ggagcaagagcctgagccccagcctgctgggctatcagcagccggccctcatggccgccccgctgtcccttgcggacgct caccgctctgtgctggtgcacgccggctcccagggccagagctcagccctgctccacccctctccgaccaaccagcaggc ctcgcctgtgatccactactcacccaccaaccagcagctgcgctgcggaagccaccaggagttccagcacatcatgtact gcgagaatttcgcaccaggcaccaccagacctggcccgcccccggtcagtcaaggtcagaggctgagcccgggttcctac cccacagtcattcagcagcagaatgccacgagccaaagagccgccaaaaacggacccccggtcagtgaccaaaaggaagt attacctgcgggggtgaccattaaacaggagcagaacttggaccagacctacttggatgatgttaatgaaattatcagga aggagttttcaggacctcctgccagaaatcagacgtaa (SEQ ID NO: 12116) gctgcagcaccctgggccacgccgatgactactgcaaactgtggcgcccacgacgagctcgacttcaaactcgtctttgg cgaggacggggcgccggcgccgccgcccccgggctcgcggcctgcagatcttgagccagatgattgtgcatccatttaca tctttaatgtagatccacctccatctactttaaccacaccactttgcttaccacatcatggattaccgtctcactcttct gttttgtcaccatcgtttcagctccaaagtcacaaaaactatgaaggaacttgtgagattcctgaatctaaatatagccc attaggtggtcccaaaccctttgagtgcccaagtattcaaattacatctatctctcctaactgtcatcaagaattagatg cacatgaagatgacctacagataaatgacccagaacgggaatttttggaaaggccttctagagatcatctctatcttcct cttgagccatcctaccgggagtcttctcttagtcctagtcctgccagcagcatctcttctaggagttggttctctgatgc atcttcttgtgaatcgctttcacatatttatgatgatgtggactcagagttgaatgaagctgcagcccgatttacccttg gatcccctctgacttctcctggtggctctccagggggctgccctggagaagaaacttggcatcaacagtatggacttgga cactcattatcacccaggcaatctccttgccactctcctagatccagtgtcactgatgagaattggctgagccccaggcc agcctcaggaccctcatcaaggcccacatccccctgtgggaaacggaggcactccagtgctgaagtttgttatgctgggt ccctttcaccccatcactcacctgttccttcacctggtcactcccccaggggaagtgtgacagaagatacgtggctcaat gcttctgtccatggtgggtcaggccttggccctgcagtttttccatttcagtactgtgtagagactgacatccctctcaa aacaaggaaaacttctgaagatcaagctgccatactaccaggaaaattagagctgtgttcagatgaccaagggagtttat caccagcccgggagacttcaatagatgatggccttggatctcagtatcctttaaagaaagattcatgtggtgatcagttt ctttcagttccttcaccctttacctggagcaaaccaaagcctggccacacccctatatttcgcacatcttcattacctcc actagactggcctttaccagctcattttggacaatgtgaactgaaaatagaagtgcaacctaaaactcatcatcgagccc attatgaaactgaaggtagccgaggggcagtaaaagcatctactgggggacatcctgttgtgaagctcctgggctataac gaaaagccaataaatctacaaatgtttattgggacagcagatgatcgatatttacgacctcatgcattttaccaggtgca tcgaatcactgggaagacagtcgctactgcaagccaagagataataattgccagtacaaaagttctggaaattccacttc ttcctgaaaataatatgtcagccagtattgattgtgcaggtattttgaaactccgcaattcagatatagaacttcgaaaa ggagaaactgatattggcagaaagaatactagagtacgacttgtgtttcgtgtacacatcccacagcccagtggaaaagt cctttctctgcagatagcctctatacccgttgagtgctcccagcggtctgctcaagaacttcctcatattgagaagtaca gtatcaacagttgttctgtaaatggaggtcatgaaatggttgtgactggatctaattttcttccagaatccaaaatcatt tttcttgaaaaaggacaagatggacgacctcagtgggaggtagaagggaagataatcagggaaaaatgtcaaggggctca cattgtccttgaagttcctccatatcataacccagcagttacagctgcagtgcaggtgcacttttatctttgcaatggca agaggaaaaaaagccagtctcaacgttttacttatacaccagttttgctgaagcaagaacacagagaagagattgatttg tcttcagttccatctttgcctgtgcctcatcctgctcagacccagaggccttcctctgattcagggtgttcacatgacag tgtactgtcaggacagagaagtttgatttgctccatcccacaaacatatgcatccatggtgacctcatcccatctgccac agttgcagtgtagagatgagagtgttagtaaagaacagcatatgattccttctccaattgtacaccagccttttcaagtc acaccaacacctcctgtggggtcttcctatcagcctatgcaaactaatgttgtgtacaatggaccaacttgtcttcctat taatgctgcctctagtcaagaatttgattcagtttggtttcagcaggatgcaactctttctggtttagtgaatcttggct gtcaaccactgtcatccataccatttcattcttcaaattcaggctcaacaggacatctcttagcccatacacctcattct gtgcataccctgcctcatctgcaatcaatgggatatcattgttcaaatacaggacaaagatctctttcttctccagtggg tgaccagattacaggtcagccttcgtctcagttacaacctattacatatggtccttcacattcagggtctgttacaacag cttccccagcagcttctcatcccttgggtagttcaccgctttctgggccaccatctcctcagtttcagcctatgccttac caatctcctagctcaggaactggctcatcaccgtctccagccaccagaatgcattctggacagcactcaactcaagcaca aagtacgggccaggggggtctttctgcaccttcatccttaatatgtcacagtttgtgtgatccagcgtcatttccacctg atggggcaactgtgagcattaaacctgaaccagaagatcgagagcctaactttgcaaccattggtctgcaggacatcact ttagatgatgaccaatttatatctgacttggaacaccagccatcaggttcagcagagaaatggcctaaccacagtgtgct ctcatgtccagctcctttctggagaatctagaggtgaacgagataattgggagagacatgtcccagatttctgtttccca aggagcaggggtgagcaggcaggctcccctcccgagtcctgagtccctggatttaggaagatctgatgggctctaacagt gcttactgcagccttgtgtccaccaccaacttctcagcatgtttctctccttggaccttgggtttccaactcttcaacct tcaggtctggggccaggagtgggacccaccatttgtggggaaagtagcattcctccacctcaggccttgggtagatttgg caaaagaacaggagcagcataggctgtttgagctttggggaaatgaactttgctttttatatttaactaggatactttta aatgatgggtgctttgagtgtgaatccagcaggctctcttgtttccgaggtgctgcttttgcaggtgacctggttactta actaggagtggtgatttgtactgctttatggtcatttgaagggccctttagtttttatgataatttttaaaataggaact tttgataagaccttctagaagcaa (SEQ ID NO: 12117) gctgcagcaccctgggccacgccgatgactactgcaaactgtggcgcccacgacgagctcgacttcaaactcgtctttgg cgaggacggggcgccggcgccgccgcccccgggctcgcggcctgcagatcttgagccagatgattgtgcatccatttaca tctttaatgtagatccacctccatctactttaaccacaccactttgcttaccacatcatggattaccgtctcactcttct gttttgtcaccatcgtttcagctccaaagtcacaaaaactatgaaggaacttgtgagattcctgaatctaaatatagccc attaggtggtcccaaaccctttgagtgcccaagtattcaaattacatctatctctcctaactgtcatcaagaattagatg cacatgaagatgacctacagataaatgacccagaacgggaatttttggaaaggccttctagagatcatctctatcttcct cttgagccatcctaccgggagtcttctcttagtcctagtcctgccagcagcatctcttctaggagttggttctctgatgc a cttcttgtgaatcgctttcacatatttatgatgatgtggactcagagttgaatgaagctgcagcccgatttacccttg gatcccctctgacttctcctggtggctctccagggggctgccctggagaagaaacttggcatcaacagtatggacttgga cactcattatcacccaggcaatctccttgccactctcctagatccagtgtcactgatgagaattggctgagccccaggcc agcctcaggaccctcatcaaggcccacatccccctgtgggaaacggaggcactccagtgctgaagtttgttatgctgggt ccctttcaccccatcactcacctgttccttcacctggtcactcccccaggggaagtgtgacagaagatacgtggctcaat gcttctgtccatggtgggtcaggccttggccctgcagtttttccatttcagtactgtgtagagactgacatccctctcaa aacaaggaaaacttctgaagatcaagctgccatactaccaggaaaattagagctgtgttcagatgaccaagggagtttat caccagcccgggagacttcaatagatgatggccttggatctcagtatcctttaaagaaagattcatgtggtgatcagttt ctttcagttccttcaccctttacctggagcaaaccaaagcctggccacacccctatatttcgcacatcttcattacctcc actagactggcctttaccagctcattttggacaatgtgaactgaaaatagaagtgcaacctaaaactcatcatcgagccc attatgaaactgaaggtagccgaggggcagtaaaagcatctactgggggacatcctgttgtgaagctcctgggctataac gaaaagccaataaatctacaaatgtttattgggacagcagatgatcgatatttacgacctcatgcattttaccaggtgca tcgaatcactgggaagacagtcgctactgcaagccaagagataataattgccagtacaaaagttctggaaattccacttc ttcctgaaaataatatgtcagccagtattgattgtgcaggtattttgaaactccgcaattcagatatagaacttcgaaaa ggagaaactgatattggcagaaagaatactagagtacgacttgtgtttcgtgtacacatcccacagcccagtggaaaagt cctttctctgcagatagcctctatacccgttgagtgctcccagcggtctgctcaagaacttcctcatattgagaagtaca gtatcaacagttgttctgtaaatggaggtcatgaaatggttgtgactggatctaattttcttccagaatccaaaatcatt tttcttgaaaaaggacaagatggacgacctcagtgggaggtagaagggaagataatcagggaaaaatgtcaaggggctca cattgtccttgaagttcctccatatcataacccagcagttacagctgcagtgcaggtgcacttttatctttgcaatggca agaggaaaaaaagccagtctcaacgttttacttatacaccagttttgctgaagcaagaacacagagaagagattgatttg tcttcagttccatctttgcctgtgcctcatcctgctcagacccagaggccttcctctgattcagggtgttcacatgacag tgtactgtcaggacagagaagtttgatttgctccatcccacaaacatatgcatccatggtgacctcatcccatctgccac agttgcagtgtagagatgagagtgttagtaaagaacagcatatgattccttctccaattgtacaccagccttttcaagtc acaccaacacctcctgtggggtcttcctatcagcctatgcaaactaatgttgtgtacaatggaccaacttgtcttcctat taatgctgcctctagtcaagaatttgattcagtttggtttcagcaggatgcaactctttctggtttagtgaatcttggct gtcaaccactgtcatccataccatttcattcttcaaattcaggctcaacaggacatctcttagcccatacacctcattct gtgcataccctgcctcatctgcaatcaatgggatatcattgttcaaatacaggacaaagatctctttcttctccagtggg tgaccagattacaggtcagccttcgtctcagttacaacctattacatatggtccttcacattcagggtctgttacaacag cttccccagcagcttctcatcccttgggtagttcaccgctttctgggccaccatctcctcagtttcagcctatgccttac caatctcctagctcaggaactggctcatcaccgtctccagccaccagaatgcattctggacagcactcaactcaagcaca aagtacgggccaggggggtctttctgcaccttcatccttaatatgtcacagtttgtgtgatccagcgtcatttccacctg atggggcaactgtgagcattaaacctgaaccagaagatcgagagcctaactttgcaaccattggtctgcaggacatcact ttagatgatgatttgtttaccagtaataattttgacttgcttcagttgagacctacgttttggccagtcccagcaggaag atatctgaggaatctagagtgaacgagataattgggagagacatgtcccagatttctgtttcccaaggagcaggggtgag caggcaggctcccctcccgagtcctgagtccctggatttaggaagatctgatgggctctaacagtgcttactgcagcctt gtgtccaccaccaacttctcagcatgtttctctccttggaccttgggtttccaactcttcaaccttcaggtctggggcca ggagtgggacccaccatttgtggggaaagtagcattcctccacctcaggccttgggtagatttggcaaaagaacaggagc agcataggctgtttgagctttggggaaatgaactttgctttttatatttaactaggatacttttaaatgatgggtgcttt gagtgtgaatccagcaggctctcttgtttccgaggtgctgcttttgcaggtgacctggttacttaactaggagtggtgat ttgtactgctttatggtcatttgaagggccctttagtttttatgataatttttaaaataggaacttttgataagaccttc tagaagcaa (SEQ ID NO: 12118) gctgcagcaccctgggccacgccgatgactactgcaaactgtggcgcccacgacgagctcgacttcaaactcgtctttgg cgaggacggggcgccggcgccgccgcccccgggctcgcggcctgcagatcttgagccagatgattgtgcatccatttaca tctttaatgtagatccacctccatctactttaaccacaccactttgcttaccacatcatggattaccgtctcactcttct gttttgtcaccatcgtttcagctccaaagtcacaaaaactatgaaggaacttgtgagattcctgaatctaaatatagccc attaggtggtcccaaaccctttgagtgcccaagtattcaaattacatctatctctcctaactgtcatcaagaattagatg cacatgaagatgacctacagataaatgacccagaacgggaatttttggaaaggccttctagagatcatctctatcttcct cttgagccatcctaccgggagtcttctcttagtcctagtcctgccagcagcatctcttctaggagttggttctctgatgc atcttcttgtgaatcgctttcacatatttatgatgatgtggactcagagttgaatgaagctgcagcccgatttacccttg gatcccctctgacttctcctggtggctctccagggggctgccctggagaagaaacttggcatcaacagtatggacttgga cactcattatcacccaggcaatctccttgccactctcctagatccagtgtcactgatgagaattggctgagccccaggcc agcctcaggaccctcatcaaggcccacatccccctgtgggaaacggaggcactccagtgctgaagtttgttatgctgggt ccctttcaccccatcactcacctgttccttcacctggtcactcccccaggggaagtgtgacagaagatacgtggctcaat gcttctgtccatggtgggtcaggccttggccctgcagtttttccatttcagtactgtgtagagactgacatccctctcaa aacaaggaaaacttctgaagatcaagctgccatactaccaggaaaattagagctgtgttcagatgaccaagggagtttat caccagcccgggagacttcaatagatgatggccttggatctcagtatcctttaaagaaagattcatgtggtgatcagttt ctttcagttccttcaccctttacctggagcaaaccaaagcctggccacacccctatatttcgcacatcttcattacctcc actagactggcctttaccagctcattttggacaatgtgaactgaaaatagaagtgcaacctaaaactcatcatcgagccc attatgaaactgaaggtagccgaggggcagtaaaagcatctactgggggacatcctgttgtgaagctcctgggctataac gaaaagccaataaatctacaaatgtttattgggacagcagatgatcgatatttacgacctcatgcattttaccaggtgca tcgaatcactgggaagacagtcgctactgcaagccaagagataataattgccagtacaaaagttctggaaattccacttc ttcctgaaaataatatgtcagccagtattgattgtgcaggtattttgaaactccgcaattcagatatagaacttcgaaaa ggagaaactgatattggcagaaagaatactagagtacgacttgtgtttcgtgtacacatcccacagcccagtggaaaagt cctttctctgcagatagcctctatacccgttgagtgctcccagcggtctgctcaagaacttcctcatattgagaagtaca gtatcaacagttgttctgtaaatggaggtcatgaaatggttgtgactggatctaattttcttccagaatccaaaatcatt tttcttgaaaaaggacaagatggacgacctcagtgggaggtagaagggaagataatcagggaaaaatgtcaaggggctca cattgtccttgaagttcctccatatcataacccagcagttacagctgcagtgcaggtgcacttttatctttgcaatggca agaggaaaaaaagccagtctcaacgttttacttatacaccagttttgctgaagcaagaacacagagaagagattgatttg tcttcagttccatctttgcctgtgcc catcctgctcagacccagaggccttcctctgattcagggtgttcacatgacag tgtactgtcaggacagagaagtttgatttgctccatcccacaaacatatgcatccatggtgacctcatcccatctgccac agttgcagtgtagagatgagagtgttagtaaagaacagcatatgattccttctccaattgtacaccagccttttcaagtc acaccaacacctcctgtggggtcttcctatcagcctatgcaaactaatgttgtgtacaatggaccaacttgtcttcctat taatgctgcctctagtcaagaatttgattcagtttggtttcagcaggatgcaactctttctggtttagtgaatcttggct gtcaaccactgtcatccataccatttcattcttcaaattcaggctcaacaggacatctcttagcccatacacctcattct gtgcataccctgcctcatctgcaatcaatgggatatcattgttcaaatacaggacaaagatctctttcttctccagtggg tgaccagattacaggtcagccttcgtctcagttacaacctattacatatggtccttcacattcagggtctgttacaacag cttccccagcagcttctcatcccttgggtagttcaccgctttctgggccaccatctcctcagtttcagcctatgccttac caatctcctagctcaggaactggctcatcaccgtctccagccaccagaatgcattctggacagcactcaactcaagcaca aagtacgggccaggggggtctttctgcaccttcatccttaatatgtcacagtttgtgtgatccagcgtcatttccacctg atggggcaactgtgagcattaaacctgaaccagaagatcgagagcctaactttgcaaccattggtctgcaggacatcact ttagatgatggtaagt ca ctctgatatgttcttgaagtagtgaagattcagggactttattctcccaagtgtcatgaa aaagtttctatggattgcttattggcatatggttgggcttttaaataagttgttattagaaatatatgttaatatataac tttgccaggtaccacggctcacgcctgtatcccagcactttggaaggctgaggcgggtggatcacaaggtcaggagttca agaccagcctggccaacatggtgtaacgctgtctctactaaaaatacaaaaaattagccaggcatggtggtgtgtgacta taatcccagctactcgggaggctgagacaggagaatcacttgaacccgggaggtggcagttgcagggagctaagatcgcg ccattgcactccagcctgggcggcagagcaagactccgtctcgggaaaaaaaaaaaaaaaaaa (SEQ ID NO: 12119) gaattccgggccgggagaaccgaacccctggcggccgcgaccccggctcccgccccggccccggcccgacccgccatgac ggggctggaggaccaggagttcgacttcgagttcctcttcgagtttaaccagcgcgacgagggcgccgccgcggccgccc cagaacactatggctatgcatcctccaacgtcagccccgccctgccgctccccacggcgcactccaccctgccggccccg tgccacaaccttcagacctccacaccgggcatcatcccgccggcggatcacccctcggggtacggagcagctttggacgg tgggcctgcgggctacttcctctcctccggccacaccaggcctgatggggcccctgccctggagagtcctcgcatcgaga taacctcgtgcttgggcctgtaccacaacaataaccagtttttccacgatgtggaggtggaagacgtcctccctagctcc aaacggtccccctccacggccacgctgagtctgcccagcctggaggcctacagagacccctcgtgcctgagcccggccag cagcctgtcctcccggagctgcaactcagaggcctcctcctacgagtccaactactcgtacccgtacgcgtccccccaga cgtcgccatggcagtctccctgcgtgtctcccaagaccacggaccccgaggagggctttccccgcgggctgggggcctgc acactgctgagttccccgcggcactccccctccacctcgccccgcgccagcgtcactgaggagagctggctgggtgcccg ctcctccagacccgcgtccccttgcaacaagaggaagtacagcctcaacggccggcagccgccctactcaccccaccact cgcccacgccatccccgcacggctccccgcgggtcagcgtgaccgacgactcgtggttgggcaacaccacccagtacacc agctcggccatcgtggccgccatcaacgcgctgaccaccgacagcagcctggacctgggagatggcgtccctgtcaagtc ccgcaagaccaccctggagcagccgccctcagtggcgctcaaggtggagcccgtcggggaggacctgggcagccccccgc ccccggccgacttcgcgcccgaagactactcctctttccagcacatcaggaagggcggcttctgcgaccagtacctggcg gtgccgcagcacccctaccagtgggcgaagcccaagcccctgtcccctacgtcctacatgagcccgaccctgcccgccct ggactggcagctgccgtcccactcaggcccgtatgagcttcggattgaggtgcagcccaagtcccaccaccgagcccact acgagacggagggcagccggggggccgtgaaggcgtcggccggaggacaccccatcgtgcagctgcatggctacttggag aatgagccgctgatgctgcagcttttcattgggacggcggacgaccgcctgctgcgcccgcacgccttctaccaggtgca ccgcatcacagggaagaccgtgtccaccaccagccacgaggccatcctctccaacaccaaagtcctggagatcccactcc tgccggagaacagcatgcgagccgtcattgactgtgccggaatcctgaaactcagaaactccgacattgaacttcggaaa ggagagacggacatcgggaggaagaacacacgggtacggctggtgttccgcgttcacgtcccgcaacccagcggccgcac gctgtccctgcaggtggcctccaaccccatcgaatgctcccagcgctcagctcaggagctgcctctggtggagaagcaga gcacggacagctatccggtcgtgggcgggaagaagatggtcctgtctggccacaacttcctgcaggactccaaggtcatt ttcgtggagaaagccccagatggccaccatgtctgggagatggaagcgaaaactgaccgggacctgtgcaagccgaattc tctggtggttgagatcccgccgtttcggaatcagaggataaccagccccgttcacgtcagtttctacgtctgcaacggga agagaaagcgaagccagtaccagcgtttcacctaccttcccgccaacgttccaattataaaaacagaacccactgatgat tatgagcctgctccaacctgtggaccggtgagccaggggttaagtcctctcccaagaccatactacagccagcagctcgc gatgccacccgaccccagctcctgcctcgtggccggcttcccgccctgtccgcagagaagcaccctgatgccagcggccc ctggcgtgagccccaagctccacgacctttctcccgctgcctacaccaagggcgttgccagcccgggccactgtcacctc ggactcccgcagccggccggagaggcccccgccgtccaggacgtgcccaggccagtggccacgcaccccggctcgcccgg gcagccacccccggccctgctgccacagcagtaaatgaaataatacgaaatgacctctccagcacgagcacccactccta gttgccacattggagcactcagttcagcaggggtatgctgacttcagcagacaaagacttttgaataaataaactgaact cacacctggtaccactcagaacctccaactgactgaatgccaggagctgaacattaatatgtgcaaagattggctctcca acaagaaggaaagcagggaggaagggagaccactgtgtcgcctggaggagaagtcatctcatgacaacagaagggaggtg gccgggctgagcacggagacccaccgtgcaggggcctttcatgggaacggcccacacgcagtttgaccccacgcccagcc cttctggcacccctggggttcaatactggaagtgccttatttaaccagaccatca (SEQ ID NO: 12120) agcaggaagctcgcgccgccgtcgccgccgccgctcagcttccccgggcgcgtccaggacccgctgcgccaggcgcgccg tccccggacccggcgtgcgtccctacgaggaaagggaccccgccgctcgagccgcctccgccagccccactgcgaggggt cccagagccagccgcgcccgccctcgcccccggccccgcagccttcccgccctgcgcgccatgaacgcccccgagcggca gccccaacccgacggcggggacgccccaggccacgagcctgggggcagcccccaagacgagcttgacttctccatcctct tcgactatgagtatttgaatccgaacgaagaagagccgaatgcacataaggtcgccagcccaccctccggacccgcatac cccgatgatgtaatggactatggcctcaagccatacagcccccttgctagtctctctggcgagccccccggccgattcgg agagccggatagggtagggccgcagaagtttctgagcgcggccaagccagcaggggcctcgggcctgagccctcggatcg agatcactccgtcccacgaactgatccaggcagtggggcccctccgcatgagagacgcgggcctcctggtggagcagcct cccctggccggggtggccgccagcccgaggttcaccctgcccgtgcccggcttcgagggctaccgcgagccgctttgctt gagccccgctagcagcggctcctctgccagcttcatttctgacaccttctccccctacacctcgccctgcgtctcgccca ataacggcgggcccgacgacctgtgtccgcagtttcaaaacatccctgctcattattcccccagaacctcgccaataatg tcacctcgaaccagcctcgccgaggacagctgcctgggccgccactcgcccgtgccccgtccggcctcccgctcctcatc gcctggtgccaagcggaggcattcgtgcgccgaggccttggttgccctgccgcccggagcctcaccccagcgctcccgga gcccctcgccgcagccc catctcacgtggcaccccaggaccacggctccccggctgggtacccccctgtggctggctct gccgtgatcatggatgccctgaacagcctcgccacggactcgccttgtgggatcccccccaagatgtggaagaccagccc tgacccctcgccggtgtctgccgccccatccaaggccggcctgcctcgccacatctacccggccgtggagttcctggggc cctgcgagcagggcgagaggagaaactcggctccagaatccatcctgctggttccgcccacttggcccaagccgctggtg cctgccattcccatctgcagcatcccagtgactgcatccctccctccacttgagtggccgctgtccagtcagtcaggctc ttacgagctgcggatcgaggtgcagcccaagccacatcaccgggcccactatgagacagaaggcagccgaggggctgtca aagctccaactggaggccaccctgtggttcagctccatggctacatggaaaacaagcctctgggacttcagatcttcatt gggacagctgatgagcggatccttaagccgcacgccttctaccaggtgcaccgaatcacggggaaaactgtcaccaccac cagctatgagaagatagtgggcaacaccaaagtcctggagatccccttggagcccaaaaacaacatgagggcaaccatcg actgtgcggggatcttgaagcttagaaacgccgacattgagctgcggaaaggcgagacggacattggaagaaagaacacg cgggtgagactggttttccgagttcacatcccagagtccagtggcagaatcgtctctttacagactgcatctaaccccat cgagtgctcccagcgatctgctcacgagctgcccatggttgaaagacaagacacagacagctgcctggtctatggcggcc agcaaatgatcctcacggggcagaactttacatccgagtccaaagttgtgtttactgagaagaccacagatggacagcaa atttgggagatggaagccacggtggataaggacaagagccagcccaacatgctttttgttgagatccctgaatatcggaa caagcatatccgcacacctgtaaaagtgaacttctacgtcatcaatgggaagagaaaacgaagtcagcctcagcacttta cctaccacccagtcccagccatcaagacggagcccacggatgaatatgaccccactctgatctgcagccccacccatgga ggcctggggagccagccttactacccccagcacccgatggtggccgagtccccctcctgcctcgtggccaccatggctcc ctgccagcagttccgcacggggctctcatcccctgacgcccgctaccagcaacagaacccagcggccgtactctaccagc ggagcaagagcctgagccccagcctgctgggctatcagcagccggccctcatggccgccccgctgtcccttgcggacgct caccgctctgtgctggtgcacgccggctcccagggccagagctcagccctgctccacccctctccgaccaaccagcaggc ctcgcctgtgatccactactcacccaccaaccagcagctgcgctgcggaagccaccaggagttccagcacatcatgtact gcgagaatttcgcaccaggcaccaccagacctggcccgcccccggtcagtcaaggtcagaggctgagcccgggttcctac cccacagtcattcagcagcagaatgccacgagccaaagagccgccaaaaacggacccccggtcagtgaccaaaaggaagt attacctgcgggggtgaccattaaacaggagcagaacttggaccagacctacttggatgatgttaatgaaattatcagga aggagttttcaggacctcctgccagaaatcagacgtaagctgcagcaccctgggccacgccgatgactactgcaaactgt ggcgcccacgacgagctcgacttcaaactcgtctttggcgaggacggggcgccggcgccgccgcccccgggctcgcggcc tgcagatcttgagccagatgattgtgcatccatttacatctttaatgtagatccacctccatctactttaaccacaccac tttgcttaccacatcatggattaccgtctcactcttctgttttgtcaccatcgtttcagctccaaagtcacaaaaactat gaaggaacttgtgagattcctgaatctaaatatagcccattaggtggtcccaaaccctttgagtgcccaagtattcaaat tacatctatctctcctaactgtcatcaagaattagatgcacatgaagatgacctacagataaatgacccagaacgggaat ttttggaaaggccttctagagatcatctctatcttcctcttgagccatcctaccgggagtcttctcttagtcctagtcct ' gccagcagcatctcttctaggagttggttctctgatgcatcttcttgtgaatcgctttcacatatttatgatgatgtgga ctcagagttgaatgaagctgcagcccgatttacccttggatcccctctgacttctcctggtggctctccagggggctgcc ctggagaagaaacttggcatcaacagtatggacttggacactcattatcacccaggcaatctccttgccactctcctaga tccagtgtcactgatgagaattggctgagccccaggccagcctcaggaccctcatcaaggcccacatccccctgtgggaa acggaggcactccagtgctgaagtttgttatgctgggtccctttcaccccatcactcacctgttccttcacctggtcact cccccaggggaagtgtgacagaagatacgtggctcaatgcttctgtccatggtgggtcaggccttggccctgcagttttt ccatttcagtactgtgtagagactgacatccctctcaaaacaaggaaaacttctgaagatcaagctgccatactaccagg aaaattagagctgtgttcagatgaccaagggagtttatcaccagcccgggagacttcaatagatgatggccttggatctc agtatcctttaaagaaagattcatgtggtgatcagtttctttcagttccttcaccctttacctggagcaaaccaaagcct ggccacacccctatatttcgcacatcttcattacctccactagactggcctttaccagctcattttggacaatgtgaact gaaaatagaagtgcaacctaaaactcatcatcgagcccattatgaaactgaaggtagccgaggggcagtaaaagcatcta ctgggggacatcctgttgtgaagctcctgggctataacgaaaagccaataaatctacaaatgtttattgggacagcagat gatcgatatttacgacctcatgcattttaccaggtgcatcgaatcactgggaagacagtcgctactgcaagccaagagat aataattgccagtacaaaagttctggaaattccacttcttcctgaaaataatatgtcagccagtattgattgtgcaggta ttttgaaactccgcaattcagatatagaacttcgaaaaggagaaactgatattggcagaaagaatactagagtacgactt gtgtttcgtgtacacatcccacagcccagtggaaaagtcctttctctgcagatagcctctatacccgttgagtgctccca gcggtctgctcaagaacttcctcatattgagaagtacagtatcaacagttgttctgtaaatggaggtcatgaaatggttg tgactggatctaattttcttccagaatccaaaatcatttttcttgaaaaaggacaagatggacgacctcagtgggaggta gaagggaagataatcagggaaaaatgtcaaggggctcacattgtccttgaagttcctccatatcataacccagcagttac agctgcagtgcaggtgcacttttatctttgcaatggcaagaggaaaaaaagccagtctcaacgttttacttatacaccag ttttgctgaagcaagaacacagagaagagattgatttgtcttcagttccatctttgcctgtgcctcatcctgctcagacc cagaggccttcctctgattcagggtgttcacatgacagtgtactgtcaggacagagaagtttgatttgctccatcccaca aacatatgcatccatggtgacctcatcccatctgccacagttgcagtgtagagatgagagtgttagtaaagaacagcata tgattccttctccaattgtacaccagccttttcaagtcacaccaacacctcctgtggggtcttcctatcagcctatgcaa actaatgttgtgtacaatggaccaacttgtcttcctattaatgctgcctctagtcaagaatttgattcagtttggtttca gcaggatgcaactctttctggtttagtgaatcttggctgtcaaccactgtcatccataccatttcattcttcaaattcag gctcaacaggacatctcttagcccatacacctcattctgtgcataccctgcctcatctgcaatcaatgggatatcattgt tcaaatacaggacaaagatctctttcttctccagtgggtgaccagattacaggtcagccttcgtctcagttacaacctat tacatatggtccttcacattcagggtctgttacaacagcttccccagcagcttctcatcccttgggtagttcaccgcttt ctgggccaccatctcctcagtttcagcctatgccttaccaatctcctagctcaggaactggctcatcaccgtctccagcc accagaatgcattctggacagcactcaactcaagcacaaagtacgggccaggggggtctttctgcacc tcatccttaat atgtcacagtttgtgtgatccagcgtcatttccacctgatggggcaactgtgagcattaaacctgaaccagaagatcgag agcctaactttgcaaccattggtctgcaggacatcactttagatgatgaccaatttatatctgacttggaacaccagcca tcaggttcagcagagaaatggcctaaccacagtgtgctctcatgtccagctcctttctggagaatctagaggtgaacgag ataattgggagagacatgtcccagatttctgtttcccaaggagcaggggtgagcaggcaggctcccctcccgagtcctga gtccctggatttaggaagatctgatgggctctaacagtgcttactgcagccttgtgtccaccaccaacttctcagcatgt ttctctccttggaccttgggtttccaactcttcaaccttcaggtctggggccaggagtgggacccaccatttgtggggaa agtagcattcctccacctcaggccttgggtagatttggcaaaagaacaggagcagcataggctgtttgagctttggggaa atgaactttgctttttatatttaactaggatacttttaaatgatgggtgctttgagtgtgaatccagcaggctctcttgt ttccgaggtgctgcttttgcaggtgacctggttacttaactaggagtggtgatttgtactgctttatggtcatttgaagg gccctttagtttttatgataatttttaaaataggaacttttgataagaccttctagaagcaagctgcagcaccctgggcc acgccgatgactactgcaaactgtggcgcccacgacgagctcgacttcaaactcgtctttggcgaggacggggcgccggc gccgccgcccccgggctcgcggcctgcagatcttgagccagatgattgtgcatccatttacatctttaatgtagatccac ctccatctactttaaccacaccactttgcttaccacatcatggattaccgtctcactcttctgttttgtcaccatcgttt cagctccaaagtcacaaaaactatgaaggaacttgtgagattcctgaatctaaatatagcccattaggtggtcccaaacc ctttgagtgcccaagtattcaaattacatctatctctcctaactgtcatcaagaattagatgcacatgaagatgacctac agataaatgacccagaacgggaatttttggaaaggccttctagagatcatctctatcttcctcttgagccatcctaccgg gagtcttctcttagtcctagtcctgccagcagcatctcttctaggagttggttctctgatgcatcttcttgtgaatcgct ttcacatatttatgatgatgtggactcagagttgaatgaagctgcagcccgatttacccttggatcccctctgacttctc ctggtggctctccagggggctgccctggagaagaaacttggcatcaacagtatggacttggacactcattatcacccagg caatctccttgccactctcctagatccagtgtcactgatgagaattggctgagccccaggccagcctcaggaccctcatc aaggcccacatccccctgtgggaaacggaggcactccagtgctgaagtttgttatgctgggtccctttcaccccatcact cacctgttccttcacctggtcactcccccaggggaagtgtgacagaagatacgtggctcaatgcttctgtccatggtggg tcaggccttggccctgcagtttttccatttcagtactgtgtagagactgacatccctctcaaaacaaggaaaacttctga agatcaagctgccatactaccaggaaaattagagctgtgttcagatgaccaagggagtttatcaccagcccgggagactt caatagatgatggccttggatctcagtatcctttaaagaaagattcatgtggtgatcagtttctttcagttccttcaccc tttacctggagcaaaccaaagcctggccacacccctatatttcgcacatcttcattacctccactagactggcctttacc agctcattttggacaatgtgaactgaaaatagaagtgcaacctaaaactcatcatcgagcccattatgaaactgaaggta gccgaggggcagtaaaagcatctactgggggacatcctgttgtgaagctcctgggctataacgaaaagccaataaatcta caaatgtttattgggacagcagatgatcgatatttacgacctcatgcattttaccaggtgcatcgaatcactgggaagac agtcgctactgcaagccaagagataataattgccagtacaaaagttctggaaattccacttcttcctgaaaataatatgt cagccagtattgattgtgcaggtattttgaaactccgcaattcagatatagaacttcgaaaaggagaaactgatattggc agaaagaatactagagtacgacttgtgtttcgtgtacacatcccacagcccagtggaaaagtcctttctctgcagatagc ctctatacccgttgagtgctcccagcggtctgctcaagaacttcctcatattgagaagtacagtatcaacagttgttctg taaatggaggtcatgaaatggttgtgactggatctaattttcttccagaatccaaaatcatttttcttgaaaaaggacaa gatggacgacctcagtgggaggtagaagggaagataatcagggaaaaatgtcaaggggctcacattgtccttgaagttcc tccatatcataacccagcagttacagctgcagtgcaggtgcacttttatctttgcaatggcaagaggaaaaaaagccagt ctcaacgttttacttatacaccagttttgctgaagcaagaacacagagaagagattgatttgtcttcagttccatctttg cctgtgcctcatcctgctcagacccagaggccttcctctgattcagggtgttcacatgacagtgtactgtcaggacagag aagtttgatttgctccatcccacaaacatatgcatccatggtgacctcatcccatctgccacagttgcagtgtagagatg agagtgttagtaaagaacagcatatgattccttctccaattgtacaccagccttttcaagtcacaccaacacctcctgtg gggtcttcctatcagcctatgcaaactaatgttgtgtacaatggaccaacttgtcttcctattaatgctgcctctagtca agaatttgattcagtttggtttcagcaggatgcaactctttctggtttagtgaatcttggctgtcaaccactgtcatcca taccatttcattcttcaaattcaggctcaacaggacatctcttagcccatacacctcattctgtgcataccctgcctcat ctgcaatcaatgggatatcattgttcaaatacaggacaaagatctctttcttctccagtgggtgaccagattacaggtca gccttcgtctcagttacaacctattacatatggtccttcacattcagggtctgttacaacagcttccccagcagcttctc atcccttgggtagttcaccgctttctgggccaccatctcctcagtttcagcctatgccttaccaatctcctagctcagga actggctcatcaccgtctccagccaccagaatgcattctggacagcactcaactcaagcacaaagtacgggccagggggg tctttctgcaccttcatccttaatatgtcacagtttgtgtgatccagcgtcatttccacctgatggggcaactgtgagca ttaaacctgaaccagaagatcgagagcctaactttgcaaccattggtctgcaggacatcactttagatgatgatttgttt accagtaataattttgacttgcttcagttgagacctacgttttggccagtcccagcaggaagatatctgaggaatctaga gtgaacgagataattgggagagacatgtcccagatttctgtttcccaaggagcaggggtgagcaggcaggctcccctccc gagtcctgagtccctggatttaggaagatctgatgggctctaacagtgcttactgcagccttgtgtccaccaccaacttc tcagcatgtttctctccttggaccttgggtttccaactcttcaaccttcaggtctggggccaggagtgggacccaccatt tgtggggaaagtagcattcctccacctcaggccttgggtagatttggcaaaagaacaggagcagcataggctgtttgagc tttggggaaatgaactttgctttttatatttaactaggatacttttaaatgatgggtgctttgagtgtgaatccagcagg ctctcttgtttccgaggtgctgcttttgcaggtgacctggttacttaactaggagtggtgatttgtactgctttatggtc atttgaagggccctttagtttttatgataatttttaaaataggaacttttgataagaccttctagaagcaagctgcagca ccctgggccacgccgatgactactgcaaactgtggcgcccacgacgagctcgacttcaaactcgtctttggcgaggacgg ggcgccggcgccgccgcccccgggctcgcggcctgcagatcttgagccagatgattgtgcatccatttacatctttaatg tagatccacctccatctactttaaccacaccactttgcttaccacatcatggattaccgtctcactcttctgttttgtca ccatcgtttcagctccaaagtcacaaaaactatgaaggaacttgtgagattcctgaatctaaatatagcccattaggtgg tcccaaaccctttgagtgcccaagtattcaaattacatctatctctcctaactgtcatcaagaattagatgcacatgaag atgacctacagataaatgacccagaacgggaatttttggaaaggccttctagagatcatctctatcttcctcttgagcca tcctaccgggagtcttctcttagtcctagtcctgccagcagcatctcttctaggagttggttctctgatgcatcttcttg tgaatcgctttcacatatttatgatgatgtggactcagagttgaatgaagctgcagcccgatttacccttggatcccctc tgacttctcctggtggctctccagggggctgccctggagaagaaacttggcatcaacagtatggacttggacactcatta tcacccaggcaatctccttgccactctcctagatccagtgtcactgatgagaattggctgagccccaggccagcctcagg accctcatcaaggcccacatccccctgtgggaaacggaggcactccagtgctgaagtttgttatgctgggtccctttcac cccatcactcacctgttccttcacctggtcactcccccaggggaagtgtgacagaagatacgtggctcaatgcttctgtc catggtgggtcaggccttggccctgcagtttttccatttcagtactgtgtagagactgacatccctctcaaaacaaggaa aacttctgaagatcaagctgccatactaccaggaaaattagagctgtgttcagatgaccaagggagtttatcaccagccc gggagacttcaatagatgatggccttggatctcagtatcctttaaagaaagattcatgtggtgatcagtttctttcagtt ccttcaccctttacctggagcaaaccaaagcctggccacacccctatatttcgcacatcttcattacctccactagactg gcctttaccagctcattttggacaatgtgaactgaaaatagaagtgcaacctaaaactcatcatcgagcccattatgaaa ctgaaggtagccgaggggcagtaaaagcatctactgggggacatcctgttgtgaagctcctgggctataacgaaaagcca ataaatctacaaatgtttattgggacagcagatgatcgatatttacgacctcatgcattttaccaggtgcatcgaatcac tgggaagacagtcgctactgcaagccaagagataataattgccagtacaaaagttctggaaattccacttcttcctgaaa ataatatgtcagccagtattgattgtgcaggtattttgaaactccgcaattcagatatagaacttcgaaaaggagaaact gatattggcagaaagaatactagagtacgacttgtgtttcgtgtacacatcccacagcccagtggaaaagtcctttctct gcagatagcctctatacccgttgagtgctcccagcggtctgctcaagaacttcctcatattgagaagtacagtatcaaca gttgttctgtaaatggaggtcatgaaatggttgtgactggatctaattttcttccagaatccaaaatcat tttcttgaa aaaggacaagatggacgacctcagtgggaggtagaagggaagataatcagggaaaaatgtcaaggggctcacattgtcct tgaagttcctccatatcataacccagcagttacagctgcagtgcaggtgcacttttatctttgcaatggcaagaggaaaa aaagccagtctcaacgttttacttatacaccagttttgctgaagcaagaacacagagaagagattgatttgtcttcagtt ccatctttgcctgtgcctcatcctgctcagacccagaggccttcctctgattcagggtgttcacatgacagtgtactgtc aggacagagaagtttgatttgctccatcccacaaacatatgcatccatggtgacctcatcccatctgccacagttgcagt gtagagatgagagtgttagtaaagaacagcatatgattccttctccaattgtacaccagccttttcaagtcacaccaaca cctcctgtggggtcttcctatcagcctatgcaaactaatgttgtgtacaatggaccaacttgtcttcctattaatgctgc ctctagtcaagaatttgattcagtttggtttcagcaggatgcaactctttctggtttagtgaatcttggctgtcaaccac tgtcatccataccatttcattcttcaaattcaggctcaacaggacatctcttagcccatacacctcattctgtgcatacc ctgcctcatctgcaatcaatgggatatcattgttcaaatacaggacaaagatctctttcttctccagtgggtgaccagat tacaggtcagccttcgtctcagttacaacctattacatatggtccttcacattcagggtctgttacaacagcttccccag cagcttctcatcccttgggtagttcaccgctttctgggccaccatctcctcagtttcagcctatgccttaccaatctcct agctcaggaactggctcatcaccgtctccagccaccagaatgcattctggacagcactcaactcaagcacaaagtacggg ccaggggggtctttctgcaccttcatccttaatatgtcacagtttgtgtgatccagcgtcatttccacctgatggggcaa ctgtgagcattaaacctgaaccagaagatcgagagcctaactttgcaaccattggtctgcaggacatcactttagatgat ggtaagttcatctctgatatgttcttgaagtagtgaagattcagggactttattctcccaagtgtcatgaaaaagtttct atggattgcttattggcatatggttgggcttttaaataagttgttattagaaatatatgttaatatataactttgccagg taccacggctcacgcctgtatcccagcactttggaaggctgaggcgggtggatcacaaggtcaggagttcaagaccagcc tggccaacatggtgtaacgctgtctctactaaaaatacaaaaaattagccaggcatggtggtgtgtgactataatcccag ctactcgggaggctgagacaggagaatcacttgaacccgggaggtggcagttgcagggagctaagatcgcgccattgcac tccagcctgggcggcagagcaagactccgtctcgggaaaaaaaaaaaaaaaaaagaattccgggccgggagaaccgaacc cctggcggccgcgaccccggctcccgccccggccccggcccgacccgccatgacggggctggaggaccaggagttcgact tcgagttcctcttcgagtttaaccagcgcgacgagggcgccgccgcggccgccccagaacactatggctatgcatcctcc aacgtcagccccgccctgccgctccccacggcgcactccaccctgccggccccgtgccacaaccttcagacctccacacc gggcatcatcccgccggcggatcacccctcggggtacggagcagctttggacggtgggcctgcgggctacttcctctcct ccggccacaccaggcctgatggggcccctgccctggagagtcctcgcatcgagataacctcgtgcttgggcctgtaccac aacaataaccagtttttccacgatgtggaggtggaagacgtcctccctagctccaaacggtccccctccacggccacgct gagtctgcccagcctggaggcctacagagacccctcgtgcctgagcccggccagcagcctgtcctcccggagctgcaact cagaggcctcctcctacgagtccaactactcgtacccgtacgcgtccccccagacgtcgccatggcagtctccctgcgtg tctcccaagaccacggaccccgaggagggctttccccgcgggctgggggcctgcacactgctgagttccccgcggcactc cccctccacctcgccccgcgccagcgtcactgaggagagctggctgggtgcccgctcctccagacccgcgtccccttgca acaagaggaagtacagcctcaacggccggcagccgccctactcaccccaccactcgcccacgccatccccgcacggctcc ccgcgggtcagcgtgaccgacgactcgtggttgggcaacaccacccagtacaccagctcggccatcgtggccgccatcaa cgcgctgaccaccgacagcagcctggacctgggagatggcgtccctgtcaagtcccgcaagaccaccctggagcagccgc cctcagtggcgctcaaggtggagcccgtcggggaggacctgggcagccccccgcccccggccgacttcgcgcccgaagac tactcctctttccagcacatcaggaagggcggcttctgcgaccagtacctggcggtgccgcagcacccctaccagtgggc gaagcccaagcccctgtcccctacgtcctacatgagcccgaccctgcccgccctggactggcagctgccgtcccactcag gcccgtatgagcttcggattgaggtgcagcccaagtcccaccaccgagcccactacgagacggagggcagccggggggcc gtgaaggcgtcggccggaggacaccccatcgtgcagctgcatggctacttggagaatgagccgctgatgctgcagctttt cattgggacggcggacgaccgcctgctgcgcccgcacgccttctaccaggtgcaccgcatcacagggaagaccgtgtcca ccaccagccacgaggccatcctctccaacaccaaagtcctggagatcccactcctgccggagaacagcatgcgagccgtc attgactgtgccggaatcctgaaactcagaaactccgacattgaacttcggaaaggagagacggacatcgggaggaagaa cacacgggtacggctggtgttccgcgttcacgtcccgcaacccagcggccgcacgctgtccctgcaggtggcctccaacc ccatcgaatgctcccagcgctcagctcaggagctgcctctggtggagaagcagagcacggacagctatccggtcgtgggc gggaagaagatggtcctgtctggccacaacttcctgcaggactccaaggtcattttcgtggagaaagccccagatggcca ccatgtctgggagatggaagcgaaaactgaccgggacctgtgcaagccgaattctctggtggttgagatcccgccgtttc ggaatcagaggataaccagccccgttcacgtcagtttctacgtctgcaacgggaagagaaagcgaagccagtaccagcgt ttcacctaccttcccgccaacgttccaattataaaaacagaacccactgatgattatgagcctgctccaacctgtggacc ggtgagccaggggttaagtcctctcccaagaccatactacagccagcagctcgcgatgccacccgaccccagctcctgcc tcgtggccggcttcccgccctgtccgcagagaagcaccctgatgccagcggcccctggcgtgagccccaagctccacgac ctttctcccgctgcctacaccaagggcgttgccagcccgggccactgtcacctcggactcccgcagccggccggagaggc ccccgccgtccaggacgtgcccaggccagtggccacgcaccccggctcgcccgggcagccacccccggccctgctgccac agcagtaaatgaaataatacgaaatgacctctccagcacgagcacccactcctagttgccacattggagcactcagttca gcaggggtatgctgacttcagcagacaaagacttttgaataaataaactgaactcacacctggtaccactcagaacctcc aactgactgaatgccaggagctgaacattaatatgtgcaaagattggctctccaacaagaaggaaagcagggaggaaggg agaccactgtgtcgcctggaggagaagtcatctcatgacaacagaagggaggtggccgggctgagcacggagacccaccg tgcaggggcctttcatgggaacggcccacacgcagtttgaccccacgcccagcccttctggcacccctggggttcaatac tggaagtgccttatttaaccagaccatca (SEQ ID NO: 12121) gaattcccaaggcgcccccgaccgcctgctacgcgggggccgcgccggcgccctcgcaggtcaagagcaaggccaagaag accgtggacaagcacagcgacgagtacaagatccggcgcgagcgcaacaacatcgccgtgcgcaagagccgcgacaaggc caagatgcgcaacctggagacgcagcacaaggtcctggagctcacggccgagaacgagcggctgcagaagaaggtggagc agctgtcgcgcgagggaattc (SEQ ID NO:1212₂) gtccttcgcgtcccggcggcgcggcggaggggccggcgtgacgcagcggttgctacgggccgccct ataaataaccggg ctcaggagaaactttagcgagtcagagccgcgcacgggactgggaaggggacccacccgagggtccagccaccagccccc tcactaatagcggccaccccggcagcggcggcagcagcagcagcgacgcagcggcgacagctcagagcagggaggccgcg cacctgcgggccggccggagcgggcagccccaggccccctccccgggcacccgcgttcatgcaacgcctggtggcctggg acccagcatgtctccccctgccgccgccgccgcctgcctttaaatccatggaagtggccaacttctactacgaggcggac tgcttggctgctgcgtacggcggcaaggcggcccccgcggcgccccccgcggccagacccgggccgcgcccccccgccgg cgagctgggcagcatcggcgaccacgagcgcgccatcgacttcagcccgtacctggagccgctgggcgcgccgcaggccc cggcgcccgccacggccacggacaccttcgaggcggctccgcccgcgcccgcccccgcgcccgcctcctccgggcagcac cacgacttcctctccgacctcttctccgacgactacgggggcaagaactgcaagaagccggccgagtacggctacgtgag cctggggcgcctgggggctgccaagggcgcgctgcaccccggctgcttcgcgcccctgcacccaccgcccccgccgccgc cgccgcccgccgagctcaaggcggagccgggcttcgagcccgcggactgcaagcggaaggaggaggccggggcgccgggc ggcggcgcaggcatggcggcgggcttcccgtacgcgctgcgcgcttacctcggctaccaggcggtgccgagcggcagcag cgggagcctctccacgtcctcctcgtccagcccgcccggcacgccgagccccgctgacgccaaggcccccccgaccgcct gctacgcgggggccgggccggcgccctcgcaggtcaagagcaaggccaagaagaccgtggacaagcacagcgacgagtac aagatccggcgcgagcgcaacaacatcgccgtgcgcaagagccgcgacaaggccaagatgcgcaacctggagacgcagca caaggtcctggagctcacggccgagaacgagcggctgcagaagaaggtggagcagctgtcgcgcgagctcagcaccctgc ggaacttgttcaagcagctgcccgagcccctgctcgcctcctccggccactgctagcgcggcccccgcggcgtccccctg gggccggccggggctgagactccggggagcgcccgcgcccgcgccctcgcccccncccccnnnnccgcaaaactttggca ctggggcacttggcagcnggggagcccgtcggtaattttaatattttattatatatatatatctatattttgccaaccaa ccgtacatgcagatggctcccgcccgtggtgtataaagaagaaatgtctatgtgtacagatgaatgataaactctctgct ctccctctgcccctctccaggcccggcgggcggggccggtttcgaagttgatgcaatcggtttaaacatggctgaacgcg tgtgtacacgggactgacgcaacccacgtgtaactgtcagccgggccctgagtaatcgcttaaagatgttctagggcttg ttgctgttgatgttttgttttgttttgttttttggtctttttttgtattataaaaaataatctatttctatgagaaaaga ggcgtctgtatattttgggaatcttttccgtttcaagcaattaagaacacttttaataaacttttttttg (SEQ ID NO: 12123) gaattcccaaggcgcccccgaccgcctgctacgcgggggccgcgccggcgccctcgcaggtcaagagcaaggccaagaag accgtggacaagcacagcgacgagtacaagatccggcgcgagcgcaacaacatcgccgtgcgcaagagccgcgacaaggc caagatgcgcaacctggagacgcagcacaaggtcctggagctcacggccgagaacgagcggctgcagaagaaggtggagc agctgtcgcgcgagggaattcgtccttcgcgtcccggcggcgcggcggaggggccggcgtgacgcagcggttgctacggg ccgcccttataaataaccgggctcaggagaaactttagcgagtcagagccgcgcacgggactgggaaggggacccacccg agggtccagccaccagccccctcactaatagcggccaccccggcagcggcggcagcagcagcagcgacgcagcggcgaca gctcagagcagggaggccgcgcacctgcgggccggccggagcgggcagccccaggccccctccccgggcacccgcgttca tgcaacgcctggtggcctgggacccagcatgtctccccctgccgccgccgccgcctgcctttaaatccatggaagtggcc aacttctactacgaggcggactgcttggctgctgcgtacggcggcaaggcggcccccgcggcgccccccgcggccagacc cgggccgcgcccccccgccggcgagctgggcagcatcggcgaccacgagcgcgccatcgacttcagcccgtacctggagc cgctgggcgcgccgcaggccccggcgcccgccacggccacggacaccttcgaggcggctccgcccgcgcccgcccccgcg cccgcctcctccgggcagcaccacgacttcctctccgacctcttctccgacgactacgggggcaagaactgcaagaagcc ggccgagtacggctacgtgagcctggggcgcctgggggctgccaagggcgcgctgcaccccggctgcttcgcgcccctgc acccaccgcccccgccgccgccgccgcσcgccgagctcaaggcggagccgggcttcgagcccgcggactgcaagcggaag gaggaggccggggcgccgggcggcggcgcaggcatggcggcgggcttcccgtacgcgctgcgcgcttacctcggctacca ggcggtgccgagcggcagcagcgggagcctctccacgtcctcctcgtccagcccgcccggcacgccgagccccgctgacg ccaaggcccccccgaccgcctgctacgcgggggccgggccggcgccctcgcaggtcaagagcaaggccaagaagaccgtg gacaagcacagcgacgagtacaagatccggcgcgagcgcaacaacatcgccgtgcgcaagagccgcgacaaggccaagat gcgcaacctggagacgcagcacaaggtcctggagctcacggccgagaacgagcggctgcagaagaaggtggagcagctgt cgcgcgagctcagcaccctgcggaacttgttcaagcagctgcccgagcccctgctcgcctcctccggccactgctagcgc ggcccccgcggcgtccccctggggccggccggggctgagactccggggagcgcccgcgcccgcgccctcgcccccncccc cnnnnccgcaaaactttggcactggggcacttggcagcnggggagcccgtcggtaattttaatattttattatatatata tatcta attttgccaaccaaccgtacatgcagatggctcccgcccgtggtgtataaagaagaaatgtctatgtgtacag atgaatgataaactctctgctctccctctgcccctctccaggcccggcgggcggggccggtttcgaagttgatgcaatcg gtttaaacatggctgaacgcgtgtgtacacgggactgacgcaacccacgtgtaactgtcagccgggccctgagtaatcgc ttaaagatgttctagggcttgttgctgttgatgttttgttttgttttgttttttggtctttttttgtattataaaaaata atctatttctatgagaaaagaggcgtctgtatattttgggaatcttttccgtttcaagcaattaagaacacttttaataa acttttttttg (SEQ ID NO: 12124) gaccagagcaatttctgcttttcacagggcgggtttctcaacggtgacttgtgggcagtgccttctgctgagcgagtcat ggcccgaaggcagaactaactgtgcctgcagtcttcactctcaggatgcagccgaggtgggcccaaggggccacgatgtg gcttggagtcctgctgacccttctgctctgttcaagccttgagggtcaagaaaactctttcacaatcaacagtgttgaca tgaagagcctgccggactggacggtgcaaaatgggaagaacctgaccctgcagtgcttcgcggatgtcagcaccacctct cacgtcaagcctcagcaccagatgctgttctataaggatgacgtgctgttttacaacatctcctccatgaagagcacaga gagttattttattcctgaagtccggatctatgactcagggacatataaatgtactgtgattgtgaacaacaaagagaaaa ccactgcagagtaccaggtgttggtggaaggagtgcccagtcccagggtgacactggacaagaaagaggccatccaaggt gggatcgtgagggtcaactgttctgtcccagaggaaaaggccccaatacacttcacaattgaaaaacttgaactaaatga aaaaatggtcaagctgaaaagagagaagaattctcgagaccagaattttgtgatactggaattccccgttgaggaacagg accgcgttttatccttccgatgtcaagctaggatcatttctgggatccatatgcagacctcagaatctaccaagagtgaa ctggtcaccgtgacggaatccttctctacacccaagttccacatcagccccaccggaatgatcatggaaggagctcagct ccacattaagtgcaccattcaagtgactcacctggcccaggagtttccagaaatcataattcagaaggacaaggcgattg tggcccacaacagacatggcaacaaggctgtgtactcagtcatggccatggtggagcacagtggcaactacacgtgcaaa gtggagtccagccgcatatccaaggtcagcagcatcgtggtcaacataacagaactattttccaagcccgaactggaatc ttccttcacacatctggaccaaggtgaaagactgaacctgtcctgctccatcccaggagcacctccagccaacttcacca tccagaaggaagatacgattgtgtcacagactcaagatttcaccaagatagcctcaaagtcggacagtgggacgtatatc tgcactgcaggtattgacaaagtggtcaagaaaagcaacacagtccagatagtcgtatgtgaaatgctctcccagcccag gatttcttatgatgcccagtttgaggtcataaaaggacagaccatcgaagtccgttgcgaatcgatcagtggaactttgc ctatttcttaccaacttttaaaaacaagtaaagttttggagaatagtaccaagaactcaaatgatcctgcggtattcaaa gacaaccccactgaagacgtcgaataccagtgtgttgcagataattgccattcccacgccaaaatgttaagtgaggttct gagggtgaaggtgatagccccggtggatgaggtccagatttctatcctgtcaagtaaggtggtggagtctggagaggaca ttgtgctgcaatgtgctgtgaatgaaggatctggtcccatcacctataagttttacagagaaaaagagggcaaacccttc tatcaaatgacctcaaatgccacccaggcattttggaccaagcagaaggctaacaaggaacaggagggagagtattactg cacagccttcaacagagccaaccacgcctccagtgtccccagaagcaaaatactgacagtcagagtcattcttgccccat ggaagaaaggacttattgcagtggttatcatcggagtgatcattgctctcttgatcattgcggccaaatgttattttctg aggaaagccaaggccaagcagatgccagtggaaatgtccaggccagcagtaccacttctgaactccaacaacgagaaaat gtcagatcccaatatggaagctaacagtcattacggtcacaatgacgatgtcggaaaccatgcaatgaaaccaataaatg ataataaagagcctctgaactcagacgtgcagtacacggaagttcaagtgtcctcagctgagtctcacaaagatctagga aagaaggacacagagacagtgtacagtgaagtccggaaagctgtccctgatgccgtggaaagcagatactctagaacgga aggctcccttgatggaacttagacagcaaggccagatgcacatccctggaaggacatccatgttccgagaagaacagatg atccctgtatttcaagacctctgtcc (SEQ ID NO: 12125) gaattccgggagaagtgaccagagcaatttctgcttttcacagggcgggtttctcaacggtgacttgtgggcagtgcctt ctgctgagcgagtcatggcccgaaggcagaactaactgtgcctgcagtcttcactctcaggatgcagccgaggtgggccc aaggggccacgatgtggcttggagtcctgctgacccttctgctctgttcaagccttgagggtcaagaaaactctttcaca atcaacagtgttgacatgaagagcctgccggactggacggtgcaaaatgggaagaacctgaccctgcagtgcttcgcgga tgtcagcaccacctctcacgtcaagcctcagcaccagatgctgttctataaggatgacgtgctgttttacaacatctcct ccatgaagagcacagagagttattttattcctgaagtccggatctatgactcagggacatataaatgtactgtgattgtg aacaacaaagagaaaaccactgcagagtaccagctgttggtggaaggagtgcccagtcccagggtgacactggacaagaa agaggccatccaaggtgggatcgtgagggtcaactgttctgtcccagaggaaaaggccccaatacacttcacaattgaaa aacttgaactaaatgaaaaaatggtcaagctgaaaagagagaagaattctcgagaccagaattttgtgatactggaattc cccgttgaggaacaggaccgcgttttatccttccgatgtcaagctaggatcatttctgggatccatatgcagacctcaga atctaccaagagtgaactggtcaccgtgacggaatccttctctacacccaagttccacatcagccccaccggaatgatca tggaaggagctcagctccacattaagtgcaccattcaagtgactcacctggcccaggagtttccagaaatcataattcag aaggacaaggcgattgtggcccacaacagacatggcaacaaggctgtgtactcagtcatggccatggtggagcacagtgg caactacacgtgcaaagtggagtccagccgcatatccaaggtcagcagcatcgtggtcaacataacagaactattttcca agcccgaactggaatcttccttcacacatctggaccaaggtgaaagactgaacctgtcctgctccatcccaggagcacct ccagccaacttcaccatccagaaggaagatacgattgtgtcacagactcaagatttcaccaagatagcctcaaagtcgga cagtgggacgtatatctgcactgcaggtattgacaaagtggtcaagaaaagcaacacagtccagatagtcgtatgtgaaa tgctctcccagcccaggatttcttatgatgcccagtttgaggtcataaaaggacagaccatcgaagtccgttgcgaatcg atcagtggaactttgcctatttcttaccaacttttaaaaacaagtaaagttttggagaatagtaccaagaactcaaatga tcctgcggtattcaaagacaaccccactgaagacgtcgaataccagtgtgttgcagataattgccattcccatgccaaaa tgttaagtgaggttctgagggtgaaggtgatagccccggtggatgaggtccagatttctatcctgtcaagtaaggtggtg gagtctggagaggacattgtgctgcaatgtgctgtgaatgaaggatctggtcccatcacctataagttttacagagaaaa agagggcaaacccttctatcaaatgacctcaaatgccacccaggcattttggaccaagcagaaggctagcaaggaacagg agggagagtattactgcacagccttcaacagagccaaccacgcctccagtgtccccagaagcaaaatactgacagtcaga gtcattcttgccccatggaagaaaggacttattgcagtggttatcatcggagtgatcattgctctcttgatcattgcggc caaatgttattttctgaggaaagccaaggccaagcagatgccagtggaaatgtccaggccagcagtaccacttctgaact ccaacaacgagaaaatgtcagatcccaatatggaagctaacagtcattacggtcacaatgacgatgtcagaaaccatgca atgaaaccaataaatgataataaagagcctctgaactcagacgtgcagtacacggaagttcaagtgtcctcagctgagtc tcacaaagatctaggaaagaaggacacagagacagtgtacagtgaagtccggaaagctgtccctgatgccgtggaaagca gatactctagaacggaaggctcccttgatggaacttagacagcaaggccagatgcacatccctggaaggacatccatgtt ccgagaagaacagataatccctgtatttcaagacctctgtgcacttatttatgaacctgccctgctcccacagaacacag caattcctcaggctaagctgccggttcttaaatccatcctgctaagttaatgttgggtagaaagagatacagagggg (SEQ ID NO: 12126) cccgggttcaagcgattctcctgcctcagcctcttgggtagctgggattataggcgtgtgccaccgtgcctggctaattt ttgtatttttattggagacagggtttcaccatgttggccaggctggtctgaaactcctgacctcaggcaatcctcctacc tcagcctctcaaagtgctgggattaccggcatgagccacgactcccggccccaaaggtcaatcttaaagctacaaggtat cttttaaaaggagtaggaataacgtattttgaggcttaaaggagtaggaatagtgtatttttagatttgaagccatcttc taaagggtacgatatttggttaacatgtcactccttatcgccatggaagaagttaattctattctttttttttttttttt gagatggagtctcactctgttgcccaggctggagtacaatggtgtgatctcagctcactgcaacctctgcctcctgggtt caagcaattctcctgcctcagcctcctgagtagcagggattacaggggttctccaccatgcctgtctaatttttgtattt ttttttttagtagaggtggagtttcaccatgttggtcaggctggtctcaaacccctaacctcatgatccgcccgccttgg cctcccaaagtgctgggattacaggcgtgagccaccatgcccagccgttaattctattcttactgcttactcccttattt tgtatgttcttcttctatcttacatcttttgcttttgctattgcttaagctagcctacgccaagggtgctctttgccccc tacttcctctgctattctcgcctcagttccgctgcattccaagctcagcctgccccagcagcaggtctctttgacaaacc tgcaattttggggaaaagtcagccccaagaaaggcagggggcccagacttatgctgtgtggcaaaagccctctttgatgg gggaaggggaggactggaaaagcagagagatctttctggatgtcctgggagagcagccctttgggtggtgggtggaggct ggaggcagggaggaatcccctcacagtgccatgagaagggcccccaaacccaggcgagacagagggagggtcaagaacgc caaggcaaatgtcacttgtgccttgttttttccctaaagaaactaaacaaagcggccgcgttcggtggcccctcaggaag gccggtcatttcctgaggagatatcaggccagcccaggccccattgttcccggtttccagccatggctgccattacctga ccagcgccacagccggtctctctgcaggcgccgggagaagtgaccagagcaatttctgcttttcacagggcgggtttctc aacggtgacttgtgggcagtgccttctgctgagcgagtcatggcccgaaggcagaactaactgtgcctgcagtcttcact ctcaggatgcagccgaggtgggcccaaggggccacgatgtggcttggagtcctgctgacccttctgctctgtgagtgttt actctgtttccacatcactttaactccatgagcatcgaag (SEQ ID NO: 12127) gaattccgggagaagtgaccagagcaatttctgcttttcacagggcgggtttctcaacggtgacttgtgggcagtgcctt ctgctgagcgagtcatggcccgaaggcagaactaactgtgcctgcagtcttcactctcaggatgcagccgaggtgggccc aaggggccacgatgtggcttggagtcctgctgacccttctgctctgttcaagccttgagggtcaagaaaactctttcaca atcaacagtgttgacatgaagagcctgccggactggacggtgcaaaatgggaagaacctgaccctgcagtgcttcgcgga tgtcagcaccacctctcacgtcaagcctcagcaccagatgctgttctataaggatgacgtgctgttttacaacatctcct ccatgaagagcacagagagttattttattcctgaagtccggatctatgactcagggacatataaatgtactgtgattgtg aacaacaaagagaaaaccactgcagagtaccagctgttggtggaaggagtgcccagtcccagggtgacactggacaagaa ag^a9gccatccaaggtgggatcgtgagggtcaactgttctgtcccagaggaaaaggccccaatacacttcacaattgaaa aacttgaactaaatgaaaaaatggtcaagctgaaaagagagaagaattctcgagaccagaattttgtgatactggaattc cccgttgaggaacaggaccgcgttttatccttccgatgtcaagctaggatcatttctgggatccatatgcagacctcaga atctaccaagagtgaactggtcaccgtgacggaatccttctctacacccaagttccacatcagccccaccggaatgatca tggaaggagctcagctccacattaagtgcaccattcaagtgactcacctggcccaggagtttccagaaatcataattcag aaggacaaggcgattgtggcccacaacagacatggcaacaaggctgtgtactcagtcatggccatggtggagcacagtgg caactacacgtgcaaagtggagtccagccgcatatccaaggtcagcagcatcgtggtcaacataacagaactattttcca agcccgaactggaatcttccttcacacatctggaccaaggtgaaagactgaacctgtcctgctccatcccaggagcacct ccagccaacttcaccatccagaaggaagatacgattgtgtcacagactcaagatttcaccaagatagcctcaaagtcgga cagtgggacgtatatctgcactgcaggtattgacaaagtggtcaagaaaagcaacacagtccagatagtcgtatgtgaaa tgctctcccagcccaggatttcttatgatgcccagtttgaggtcataaaaggacagaccatcgaagtccgttgcgaatcg atcagtggaactttgcctatttcttaccaacttttaaaaacaagtaaagttttggagaatagtaccaagaactcaaatga tcctgcggtattcaaagacaaccccactgaagacgtcgaataccagtgtgttgcagataattgccattcccatgccaaaa tgttaagtgaggttctgagggtgaaggtgatagccccggtggatgaggtccagatttctatcctgtcaagtaaggtggtg gagtctggagaggacattgtgctgcaatgtgctgtgaatgaaggatctggtcccatcacctataagttttacagagaaaa agagggcaaacccttctatcaaatgacctcaaatgccacccaggcattttggaccaagcagaaggctagcaaggaacagg agggagagtattactgcacagccttcaacagagccaaccacgcctccagtgtccccagaagcaaaatactgacagtcaga gtcattcttgccccatggaagaaaggacttattgcagtggttatcatcggagtgatcattgctctcttgatcattgcggc caaatgttattttctgaggaaagccaaggccaagcagatgccagtggaaatgtccaggccagcagtaccacttctgaact ccaacaacgagaaaatgtcagatcccaatatggaagctaacagtcattacggtcacaatgacgatgtcagaaaccatgca atgaaaccaataaatgataataaagagcctctgaactcagacgtgcagtacacggaagttcaagtgtcctcagctgagtc tcacaaagatctaggaaagaaggacacagagacagtgtacagtgaagtccggaaagctgtccctgatgccgtggaaagca gatactctagaacggaaggctcccttgatggaacttagacagcaaggccagatgcacatccctggaaggacatccatgtt ccgagaagaacagataatccctgtatttcaagacctctgtgcacttatttatgaacctgccctgctcccacagaacacag caattcctcaggctaagctgccggttcttaaatccatcctgctaagttaatgttgggtagaaagagatacagagggg (SEQ ID NO: 12128) tcttttggttttgctattgcttaagctagcctacgccaagggtgctctttgccccctacttcctctgctattctcgcctc agttccgctgcattccaagctcagcctgccccagcagcaggtctctttgacaaacctgcaattttggggaaaagtcagcc caagaaaggcagggggcccagacttatgctgtgtggcaaaagccctctttgatggggcaagggtaggactggaaaagcag agagatctttctggatgtcctgggagagcagccctttgggtggtgggtggaggctggaggcagggaggaatcccctcaca gtgagaagggcccccaaacccaggcgagacagagggagggtcaagaacgccaaggcaaatgtcacttgtgccttgttttt tccctaaagaaactaaacaaagcggccgcgttcggtggcccctcaggaaggccggtcatttcctgaggagatatcaggcc agcccaggccccattgttcccggtttccagccatggctgccattacctgaccagcgccacagccggtctctctgcaggcg ccgggagaagtgaccagagcaatttctgcttttcacagggcgggtttctcaacggtgacttgtgggcagtgccttctgct gagcgagtcatggcccgaaggcagaactaactgtgcctgcagtcttcactctcaggatgcagccgaggtgggcccaaggg gccacgatgtggcttggagtcctgctgacccttctgctctgtgagtgtttactctgtttccacatcactttaactccatg agcatcgaagcttctggaatcaacatgtttcttatgtttcttgcaggttcaagccttgagggtcaagaaaactgtaagtc tgatgtttccactgtaacagatgtttctacctggcttcctcctttctcttctgtgatgcctaaaacgcacattaaattgc tggggtttgatacttctaacaattaaggaaaagaatccaattgagaactaaagtttatcccatgtgggcatttttagaaa ggcttagatctaagccaagttctggtcagtgtgttttagaagtagcacacgtttccttggctggtctgaaagtagtgggt tatcttgatgaattgtttagtcagttacagatcaaactccatgttcttttctctgttctcacgactactcttgactagtc taaaaatatattaggttgttgaaaagtaattgtggtttttgccattactttttaaaagatggcaaaaaacacaattataa gtagcacacattttcttttttttttccttttttttttgagacagagtctctgttacccaggctggagtgcagtggtgcaa tccggctctctgcaaactccgcctccagggttcaagggattctcctgtctcagcctcctgggtcgctggaattagagg (SEQ ID NO : 12129) ttggcaggctggtctcaaactcctgacctcaggtgatccgctggcctccacctcccaaagtgctgggattacaggtgtga gccaccacgcccggcctcacattttctagatttcagtgcattgctgttttttgggatggggaagtgatttttttatttta atgagcaattccataattagttttttgttgttttaccataatggcttatttgaatattgtaaggtatccccaactgtttt tatttgcaaatgagatataattgatttgttagacatatgaagacagatcctagtttaaattgttgctactttttttactc ctaaatgataaaaatcacacactcgagctc (SEQ ID NO:12130) ttggcaggctggtctcaaactcctgacctcaggtgatccgctggcctccacctcccaaagtgctgggattacaggtgtga gccaccacgcccggcctcacattttctagatttcagtgcattgctgttttttgggatggggaagtgatttttttatttta atgagcaattccataattagttttttgttgttttaccataatggcttatttgaatattgtaaggtatccccaactgtttt tatttgcaaatgagatataattgatttgttagacatatgaagacagatcctagtttaaattgttgctactttttttactc ctaaatgataaaaatcacacactcgagctc (SEQ ID NO: 12131) gctgtcccacagcccacccttcatcacaatagtcctgaaactttttgggttcagtaaggaaatctgtgggccttctctcc agaaaaagcacacatttgcacacaattggaggtagttgatgagcctcctaacacccacccatgcacctcccaggggctgt gtcccccaggttgtgaacagtcactctgtgtaaatagtgagacctacaggcagtaattcagtttggctgtgcttggctgg tttatttagaaagatgataatgttt (SEQ ID NO: 12132) gagctctccaagggcagacactgccagcctcactgttctctgaacccccagtatgggacagtgcttggcacagaaaaacc cccttaaatgtttgctatgaatggtgctaaggaagaaggcagagaatgtcaaccagaggccaggcactggcaatatatac acggcccc (SEQ ID NO: 12133) ataccttggctcactgcaacctctgcctcccaggttcaagcagttctcctgcctcagtctcccaagtagctgggattaca ggcgcccaccaccacacccggctaattttgtatttttagtagagatgaggtttcaccatgttggccaggctggtcttgaa ctcctgacctcaagtgatccacccgcctcggcctcccaaagtgctgggattacaggcataaaccaccgtgcccggctggt cca (SEQ ID NO: 12134) gagctcatccagcaggcttcttaaatcaggagcttgtaagttgcatataaagacaaaaaagggagttccaaagagtaatg ctgtgggaaatgacttgaatttaaaccgtcaccttgtttgatctcatggactggtcagacaccatttttgttgtcgttgt tgttgttaaattaattgctcagaatatagcagcaggcgcaaattgtagtactcgttttaaaattgaagattaaattttaa attacccaacaaaggcctaactttgttaaaag (SEQ ID NO:12135) gaattctaccgacagcctatggttactggatataagccaattctgttctggggacttgccagaaatgacacaattggcca gttgacccacagcctagttcctagcagagattggatagctgattgagcgttgtggctgttttgaggcttgaccagagatt cctgccgttggcagaggggaatctgtagtctttgcttcttggtagcaggtgaggctgaaaacgcaagtagcaggctaaaa actggtttcaagtcctcaccatctggtgaaacctcagagcσcatcagatagaaaatgccagctgggactgtgctaattcg gtaaggcctgggtggagaaggagggcctgggcacgaccatctggtttcggaatggaggtagcagtcatttattaagtact taatgtatatcgggcactgtacaggagacgttctggctgttctcctgtacatttcctgcaaagacctaatgagatatgat tactccatcctacaggtaaggaaactgagctcagagagtctagctgcccagggtcacacagtaaatgatgagccaggact tgaacacttgactgcttgaatcctgtactccctccaggggccaagatgtggcagctcacagaatgcctatatcttttttt ttttttgtcttttgagacagtctcactctgttgcccaggctggagtgcagtggtgagatctcacctcactgcaacccccg cctcccaggttcaagtgattcttgtgcctcagcctctcaagtagctgggttacaggcctgcaccaccaaacctggctaat ttttgtatttttagtagagagggggtttcaccatgttggccaggccagtctctaactgctgacctcaggtgatccaccca ccttggtctcccaaagtgctgggattataggcgtgagccaccatacctagctctacatctttatcactctgttcctttgc cttggtgggaaaagttgcagcttagtaccaactgcctcctgcttgagccactgtgcacagttactatcagcctggccctg taggcacgtagaacccctggactcaatactgcataggatgggataagaccacatctgatgtggtgaaggtcaccgggatg atgttgtttctgagataacaggtatgtctgccttccttcgggttgcatttagctttcacaatcaacagtgttgacatgaa gagcctgccggactggacggtgcaaaatgggaagaacctgaccctgcagtgcttcgcggatgtcagcaccacctctcacg tcaagcctcagcaccagatgctgttctataaggatgacgtgctgttttacaacatctcctccatgaagagcacagagagt tattttattcctgaagtccggatctatgactcagggacatataaatgtactgtgattgtgaacaacaaagagaaaaccac tgcagagtaccagctgttggtggaaggtgagtccttggaactgagcacaggcaagcagatggagcatagcacacagtggc gtgaataacagctgtgaatgaatagtgacactggacttaactctccacccatcaccctctcattcatctgcctggcattt tccttacctgaatacgtaagcactagacatattccccaataggcaggcccttccttccttccttccttccttccttcctt ccttccttccttccttccttccttccttccttcctttctttctttgatggagtctcactctgtcacccagtctggagtgc agtgggtgatctcggctcactgcaacctctgcctcccaggttcaagcgattctcctgcctcagcctcccaagtaattggg attacaggtgtgtgccaccacacctggctaattttgtatttttagtagagatggggtttcactgtgttggtcaggctggt ctcgaactctgacctcaagtgatccacctgcctcccaaaatgcttcttcatctcgctctataaattacaatttctttctt caagactcaactcaatgatgttttgccaaaacaaaatgggtctaccccagggtgccagtcagtacagctctgatgctctc tctacaggcaatggtatttgtgtgtataaaggccacagcggtgtgttaagacacctcgttctgcagtcactctgcctggg tttcaatcttgggtcaagtccttaacatgctctaaacttcaaaatcctcaccagtaaaaggaagataacaacgataccca tttcaggcaattattgagagggttaaaagtgtcatgtgggtagagtgcttagcaaaatttccagcacctagtgagttcct aataaatagaaatgtatttatttatttgagacagagtcttcctctgtcacccaggctaaagagcaatggcgcgaccttgg ctcactgcaacctctgtctcctgggttcaagcgattctcctgtctcagcctcccaagaaactgggattacaggcacgcgc cactgtgcctggctaattttttgtatttttagtaaggatggggttttaccatgttggccagcctggtctcgaactcctaa cttcaagtgatttacccaccttggcctcccagagtgtcaggattacaggtgtgagccaccatgcccggtccacaaatatt ctatttcactcagtattggcatccgttcttacacatctgtctgctcttctggatagtgaaattgtaaagacagagatggt gtttgggtttattcttatatcttgaacaatgaatctggctcatagtaggcattcagtcaatgttcatggaataaattaaa gtcagtcctagcctgtgggtgcattcaataaagggtaacaacaatcacagtgacactgacaaatactgggttacctttcc cctctaagcatcatctgttgggaatctgattgtgtcctcttcccaataggattataaaccattgaaaacaccaagtacat cttgaccatattttattttttaaatttatttatttatttatttatttatttttagacagagtctcactctgttgcccagg ctggagggcagtggcacgatctcagctcactgcaacctctgccttcggggttcaagcaattctcctgcctcagcctccaa gtagctgggattacaggtgcctgccaccatgccggctaattttgatttaatagagatggggttcgccatgttggccaggc tggtctcaaactcctgacctcaggtgatccacctgcctcagcctcccaaagtgttgagattacagatgtgagccacctcg cgtggccttagtggtgattttggtggacccatcacccgagcagtgtacactgtacccagtgtgtagtcattttatccctc gctccctcccactctttcccctgagtccccaaagtccactgtatcattcttatgcctttgtttcctcatagcttagctcc cattgagcatattttatattttttcctttcttttcttctcttttttgagacagggtctctgttgcccaggctggagtgca gtggtgggattactgctcactgccgcctcaacctcctaggctcaagtgattctcccacctcggcctcccaagtagctggg actaccagtgcacaccactaactacccctggctaattttaatttttttttttgtagagatagcatttcaccgtgttgccc aggctggtctccaactcctgggctcaagagatccacccacctcagcctccagattttatatatttcaaagtgcctagtac tgtgctgggcacatacctgttcatttattacctggtaggtcgcactgggtgttcagagaacaaaaaagagccctctcatg ggatcaactacagtcactcagcggaggggagggcttgtgtctctcaatcaggctgatactgacagactttcttcttcaat caggctgatactgacatgactttctactttccccgtaggagtgcccagtcccagggtgacactggacaagaaagaggcca tccaaggtgggatcgtgagggtcaactgttctgtcccagaggaaaaggccccaatacacttcacaattgaaaaacttgaa ctaaatgaaaaaatggtcaagctgaaaagagagaagaattctcgagaccagaattttgtgatactggaattccccgttga ggaacaggaccgcgttttatccttccgatgtcaagctaggatcatttctgggatccatatgcagacctcagaatctacca agagtgaactggtcaccgtgacgggtcagcatctgctcccttcctcatcgttctttgtggtttctggt (SEQ ID NO: 12136) gttctagagaagaaaggttgaattttaaagttagttaggaacaatagaaaagtttgaaaaggggaagcagcaaaaagagc agaagaggctcctcttgcccaggtttgcacctgagtccaaccaggttgtcttcctctcttgcagaatccttctctacacc caagttccacatcagccccaccggaatgatcatggaaggagctcagctccacattaagtgcaccattcaagtgactcacc tggcccaggagtttccagaaatcataattcagaaggacaaggcgattgtggcccacaacagacatggcaacaaggctgtg tactcagtcatggccatggtggagcacagtggcaactacacgtgcaaagtggagtccagccgcatatccaaggtcagcag catcgtggtcaacataacaggtagggctgctgctgccggagggtgttggcatatggcgggctcaagaggccaccatgctg caatccagcatggccaaagagagctgatcatttcctgcccctgcttatctgaatgaatgtgctcagatggggctttggtg ctcgtgggaggaaaccactgcagagcgagttaacagtctactgtgcgtgttgagggtacaggctccggcaccaaagctta accctgccgctcactgcttctgtgaccttgggtgagttattgaacgtgccgcagcgctgtgagatggtgataatgacctt ttaggactgctataatgattaatgagataactatactgtaagcatgagctgagagatttgtacagagtaagactctgaaa cactggttaatgttttcattactctgttatatttctccatcccctgtgacaagcactatgctagatc (SEQ ID N0:12137) gaattccggcctgtgaatccatctggttcttggactttttttggttggtaagctattgattattgccacaatttcagatc ccgttattggtctattcagagattcaacttcttcctggtttagtcttgggagagtgtgtgtgttgaggaatttatccatt tctcctagattttctagtttatttgcgtagaggtgtttgtagatattctctgatggtagtttgtatttgtgtgggatcgg tgatgatatcccctttatcattttttattgcgtgtatttgattcttctctctttttttctttattaggcttgctagcggt ctatcaattttgttgatcctttcaaaaaaccagctcctggattcattaattttttgaagggttttttgtgtctctatttc cttcagttctgctctgattttagttatttcttgccttctgctagcttaaggagtttcattcttgttgcccaggctggagt gcagtggagcaatctcggctcactgcaatctctgtctcctgggttcaagggattctcttgcctcagcctcccgagtatct gggattacaggcgcccaccaccatgctggctaattttatatttttagtagagatggggtttcaccatgttgcccaggctg gtctcaactcctgacctcaggtgatccacccacctctgcctcccaaagtgctgggattacaggcatgagccaccacacct ggccacaagttgcaaaacttttctaatccttgtcattgaaataaattggattaacaagaaaggaaaacctgccattggaa tcctaggcaaagaatgaaccctagctccttactggggtgatcgttaggtacatgagaagcaaaggaaaactttttgctgg aagttggaagttggttctgccaagagcacctgagccaagggcctctccaggaagggtctttagggtggtggccagacaca tctcgctccattcccactcactgtttttcagaactattttccaagcccgaactggaatcttccttcacacatctggacca aggtgaaagactgaacctgtcctgctccatcccaggagcacctccagccaacttcaccatccagaaggaagatacgattg tgtcacagactcaagatttcaccaagatagcctcaaagtcggacagtgggacgtatatctgcactgcaggtattgacaaa gtggtcaagaaaagcaacacagtccagatagtcgtatgtggtgagtatattgttgcgactcagaggacatccggggttga atgggagaaaggaaatttatctgcagctgccgccctctccggtctccggtctgagcagactcaggcagggtaagaactag agggagagaagtgcgaaatcaaaggccaaagaaacaaggaggtattcctgctcagaacactgattcactgatgatgatgt ggcctctgacttgcaagattctggcaagattctgcctcctggagcaagacccacccaaaagttcaggaaggaaacactac ttagtcaatgttaaacttttcttttttttttttgagacgtgtcgcccaggctagagtgcagtggcacgatagctcactgc aacctctgcctcctaggttcaagtgatctcctgcctcagcctcccaagtagctgggattacaggtgcccaccaccacgtc tgcctaatttttgtatttttatttttattacttttatttatttatttatttattttttttcggtctgtcacccaggctgg cagtgccagtggcacaatctgggcatcactggaaagcatccgcactcctgggtacacgagcattctcctgcctcagccct cccaagtgggtgtggactacaggacacaccgt (SEQ ID N0:12138) tcacttgagtccaggagttcaagaccagcctgagcacatagtgagaccctgtctctacaaaaaataaagaattagccagg tgtggtgtgcacctatagtcccagctactcgggaggctgaggtaggaggattgcttgattctgggaggttgtagtgagct gtcatcgcaccagtgcactccagcctgggtaatagagtgagaccctgtctcaaatacacacacacacacacacacacaca cattttgttggctacttgttgtactttttctatgttttctgtgtctttgctcaacacaagaaaagtatattatgtgtgca tgtgcgtgtgagatatggtaaaatatgaacatgtatttctggggatgtaatgttttccttgaatttctgtcattctctgt tttgcttattgtacttctctttccctttcccttctcaccacacacacacacacacacacacacacacacacacagcctgt cagtctcataggtgtcctataaaggtaaatggcaggcaggcatttgaaattacagcagggatagaaagcaaaactcaggc tttggaggaggaacctcttgtgctggatgctttgtttttaccttcagtgccttttggattgtttctccctctgttctaga aatgctctcccagcccaggatttcttatgatgcccagtttgaggtcataaaaggacagaccatcgaagtccgttgcgaat cgatcagtggaactttgcctatttcttaccaacttttaaaaacaagtaaagttttggagaatagtaccaagaactcaaat gatcctgcggtattcaaagacaaccccactgaagacgtcgaataccagtgtgttgcagataattgccattcccacgccaa aatgttaagtgaggttctgagggtgaaggtgataggtaagttgctgtgctgtgagaagaaatcatgtgggcttggggcat tctttcacccccagggactgtggggacaataagagaagtagggggccaggtgcggtggctcatgcctgtaatcccagcac tttaggaggccaaggccggtgaatcattgaggccaggagttcaagaccagcctggccaacatggtgaaaccccatctcta ctaaaaatacaaaaattagctgggcatgatggcgtgcgcctataatcccagccactcgggaggctgaggcaggagaattg cttgaacccaggaagcacaggttgcactgagccaagttgcgccattgcactccagcctgagcaacaagagcgaaactcca tctaaaaaaaaaaaagcgagagaagtagtgggtgcttatgcaaagtccatatactagatatgcaccaaagcagggccaag gttcagtaaaggaggctggaaaatatttgggggctattgatgaggacaatataatctctttccagaacctttcaacaaac tgctaaaagatgataagcatgaaagtgtcctgactgcaggaagcactgaagttgtgcatatgggcttcccttagcacttt ctccttttcagatacactgttctgagaattgtagatcaggactctgctgttgtgactcctagccggggaaccctgccttg tgtgaattcgagattagcctggccaacatggtgaaatcctgtctctaataaaaatacaaaaaattagctgggtgtggtgg tgggcacctttaatgccagctactcgggaggctgaggcacaagaatcatttgaacctgggaggcagaggctgcagtgagc caatatcattccgctacactccagcctgggcaacggagcaagactccatctcaaaaaaaaaaaaaattaacattacatag actaagcacctaatggtgtgaggcatacaaaaaagaagacatattctttgtttcaatgctgtggtaagaaacacaagctc tcctaatgaaaatgatggacaaacatctgaatcatactaccaataagcatagaaaaaatgttgggggtcatgtttggttg tcacgtgaactatatccttacagtgatggtgatagtaatttagggtatgccagacttcatctagcttaagtgggtaaaca ttgtgaaaaagctgggctaggtgccagggcttgagaatgggtggccagagaaggctgaagatggctgaacatctccagca aacacatgagccaaaaggtcccatggggcacttcaaaagactgtgcgcagccaggtgcggtggctcacgcctataatccc agcactttgggagaccgaatggggtggatcacttgagcccagaggtttgtgactagcttggccaacatggcaaaaccccg tctctactaaaaatacaaaaattagcccagcgtggtggtgggtgtcctgtagccccagctactcaggtggctgaggtggt agaatcacttgaatccaggaggcagaggttgcagtgagccaagatcgtgccactgcactccagcctgggtgacagagtga gactctatctccacaaaaaaaaaaaaaaaaaaaaaaattaaaggactgtggccaaatcagatggctggaaacaaaggctg gagtttgggaatggagaatcaccggatatgagctgaaaaagtggctgagcctaagcgtgacaggtgtcaggtgccagtct caggagtaggcaattgtcctgcatgcagtgaaaagccagaagatggaaggaaggacaggatgcaaatgagttctcggaac gatccacctggtggctgggtcagggagcaggcatggtgacttcagacctcatggtacgttagaggctaatgtgaagccca tgtgaagctgttggtttaaactgggtcgatatcagtggcacacatttactgaccatgtgtccagccctgtgtgaagtact gtagtaaattgctccaatggaaactcacaataaccacagaaggccagtaacagcattgtcgttattttatcatgacgcaa ctgaggcttagggcagacagctggtgggtggtgggactgggatttgagcccactggtgtcccaggcccggagcttggctt cttccattgtcttaccacagcctgcactcacaggagagtgactcataagttacaataccatctgctgaccatctgctctc acactagaaggaaagtctacttggggagacaatttaggatccgaattttggtagttgaggatggagctaggaaaagcgga tacaggaggtagccaagttctgcttggacctgcagggagtgaggctggccgggctccaggtggaaatccccaggtgaaaa gggagacttggagttcaggaaagtaacctggactggagccataggtttaggtgtcagtggctcagagacagaagctcagc gtgtaggtgaaatcacccaggaggagaatggggatggaaaactgaggattgaattttgcaaaatgt catacttccgggg aaaacaaagaataaccagtgaataagaaaggggtgccaggtaagaagggaagagaatcagagtcatgaggaaccccagaa ccccagaaaaagctgagttccacgtaagacctgggcaacagtgaagtatggagagcccaagattgggagcgtggaggaag agcatccaccactgaatttaatcagccccggactcagggacgttggttggggaatcaagtgaccttcccagtttcttcaa aacttgagagagagtgcagtgtcacaagattgtgactacaaaagagtgcagtcagatttcaggggtaacaagaaagtgtg aaataagggagtcaaagcataaaggaaaaaggagaaaaaatggccgatagctagagaaggcgtgggtcaagattgtctgt ggcctggcatggtggcttatgcctgtaatcccagcattttggaaggccgaggtgggcaaatcacctgaggtcaggaattc aagaccagcctggccaacagggcaaaaccccgtctctaaaacaacaacaacaacaaaaaaatccaaaaagttagctgggc ctggtgggcgcacctgtcattccagctactcgggaggctgaggcaggagatttgcttgaacccaggaggcacacgttgcg gtaagctgagattataccactgcactccagcctgggtgataagagcgggactctgtctcagaggaaaaaaaaaaaagttg agcagtggctgtctcatgttcctcttcctctgcccttctttgctcagtgtgaatccttttcctgcttttcagccccggtg gatgaggtccagatttctatcctgtcaagtaaggtggtggagtctggagaggacattgtgctgcaatgtgctgtgaatga aggatctggtcccatcacctataagttttacagagaaaaagagggcaaacccttctatcaaatgacctcaaatgccaccc aggcattttggaccaagcagaaggctaacaaggaacaggagggagagtattactgcacagccttcaacagagccaaccac gcctccagtgtccccagaagcaaaatactgacagtcagaggtgagtcagggtctccatagcaagctgtgctgtgggcccc caagggcaagaccagaaaacaccccccttgtaagagggagtttggggggagtctagcttatgtgactgaaggctaggaga gtaatgtcctccaggctcttggttgcaagtgacagaaacccactcaaattaagtaaaaaagagaaatcgattattataag gaattgggagaatgtcacatcgttccaattacaaattgttggcagactcaccattgagtcatcttgggtcaaacatccaa ccacagaccacctgtagccaaggggattgggtcacgcagaacagacatgattggggaaccacttatgtgggtgtgggggc ggtttcctggagaagaagagggctgaaaacacatgccaaaaaggagtctactccacttgagccctggagttggagaccag cctgggcaacatggtgaaaccctgtctctacaaaaagtacaaaaataggctgggcgcagtggctcatacctgtaatccca gctactcgggaggctgagacatgagaatcacttgaacccaggaggtagaggttgcagtgagcagagcttgctccactgca ctccagcctgggcaacagagcaagactctgcctcaaaaatcaaaccaacaaaaaatagctgtgtgtggtggtgtgctcct gtagtcccagctactcgggaggctgaggtggaaggattgctcaagcccaggaagttgaggctgcagtgagctgtcatcag cctctagcctgggtgacagagtgagaccctgttcaaaaagaaagaaaaagaaaagagtctacccagcaaagctggtttgt tccctccttgaggaccacagctgacctctatttgtagcagaaacaatcatttctgcaccagctctgagtgcagaacccct cagaggtagatggatgctaaggcaagctgccagttacaagagctgtgagaatcagactgacttttgttgcttaaggcctg atattatttcttcctggcagaggaagagcctatatacaaaaaaaattttttgttttgttttgttttcagtcattcttgcc ccatggaagaaaggacttattgcagtggttatcatcggagtgatcattgctctcttgatcattgcggccaaatgttattt tctgaggaaagccaagggtgagcatagttctttccttccatactgactggtcgtccttgccaggaaaccagccagggatg cgtggtgcttttctgacccctggattcagctaggcaaaaatgaaagctattattttcctcattgggcaaaccagaaaaga taaaatttgggggaaattacatctttgtgtggttagaagaagccatttctgtagatttgtccacacctagtcctgtaatg cgtgtagagtggggtgcaagcgtcttggagacacacaaacatgcgcataacacccacatgttgcacacacacattg (SEQ ID NO:12139) acctctttcttttctgtcttttgaaaaagagtgaatatatttgccttctttttctctctttttctgggtattcaatcttc tgggaagtccaaacgtagctgaaaagagtgttccttcacagcttactaggagtaaaacaaaaagaaaagaaaagtgtttt ctatctattaggttagtgcaaaagccattggcgttttggccattatagtggtatggatgtgggtactgtatactgacttt ggtttttcgttttctgtttttaaagccaagcagatgccagtggaaatgtccaggtgagtgtatttgtaagaagggggcgg ctgctctgtgagcacggtggacatgtctggagggagattctggtcattaggaagttttcagtggctcttggcaaacttag aaaaatataggccttccttgggtgtgagttgtgtgtgtgagttgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtatctc cgtggaagaatgccaattgtcctttcatgggaaggaatggcttttattctgagatcatgtccttcctacatgattatttg tgaaatctccctttctttatgaaattataatggtagtagataattttttaaaatttgacaaaatagagttggcctttaaa aaatggttttactacctttactgttgttgaaatcccaaatcaaaagtatagaaatgattgctctgttccagagagaaaca gtagcgtgggataagaatttcagggggcttggtagtagcctgtgaaggactccggtattcatgtgtgctttggtctgatg ttatttaataggaaagtt (SEQ ID Nθ:12140) aaaaaaaaaaaaagtttttttacataatccttggagctgccaaaaaatatttgttttccaaatgagagagtaaagttttc cttaccttggaaaactcttcctggttttctcatgatcttcccttgtttactttggtggtttggggttagaacaataacaa caacaaatatatctatatattgttttctgtttttatatttcattttaaaggccagcagtaccacttctgaactccaacaa cgagaaaatgtcagatcccaatatggaagctaacagtcattacggtaaagtcatgttctcctgccatttataattccccc caacttgctacatacttccttacccctctcagaagcagaatatgtaagtggtgggattacagttggaagagaaaccctgg cttcaacagggtacttcatctcatcagccactgggccatgtaatatacggaaacgtaaaaggaaaggtaacatattttat tctaactttgccaccttccaaactccccgtagaagaaagatggagaataatcataatgccttcaaagactttgaacattg ctccagcgtaatattataattctccattttcaagacagagacagatattgaatgaaacattggtaaacatcttctcagat ggaattattacaagcacaagacagttttacttcaaatttggcacaaagggaaagcaatttcaatattctctcagtaaagg cataaataaagtgttccaactaagaaaatatctattcataaggctcatcagtagcttcagggtcagctcagctgaatgag taggcagtcctaggagttcttaatcccaggttagtaagaaaattgctcaagcatttcagcaggatgctacttacttccca gaggggggtattattacatcacaaaaagtcctgtcccagaccaaatttggggacactcttcctctt (SEQ ID NO: 12141) atagccacgactcaaatatattgatcttagaatctaaaagacttaggtctgggcgcggtggctcacgcctgtaatctcaa cactttgggaggccgaggtaggtggatcacttgaggtcagcagttcaaaaaccacctggccaacatggtgtaaccctgtt tctactaaaaatacaaaaaattagctgggcatggtggtagatgtttataatcccagctactcaggcaggctgaggcagga gaatacccttgaacctgggaggtggaggttgcatgacctgatggacctcaacatgcacaccagtccgagcaacaagagcg aaactccatctcaaaaaagaaagaaagaaagaaactatattcaggccaggcatggtagttcatgcctataaccccagctc tttgggaggctgaggtgggaggatcattgagcccaggagttggagaccagcctgtgcaacaaagcgagacatggagaatg tggaacgagggacccaggacccagagacagtgctggttgtcactacactgaataaatcaggcttgactttgttaggggta ctgaatttttaaaagggttttagaaaactagaatttcccttgtcactcaccctaattgttatttttcaactaggtcacaa tgacgatgtcagaaaccatgcaatgaaaccaataaatgataataaaggtaattatctaattacatgtttttattagaacc aacttttacattaaaaaaaagactcataggaaaagaaaactaaaacttgaaggactgtggataatttcccacctctctta atgaccctgtacccagccgatgtgtcaatgaaggtagctagctgctttcaccagagatgctatctagtgtcctcagtggg aagtacctaaatcaaagtagggaagaactgggttatactcaaaaaa (SEQ ID NO: 12142) acaacaactctgtggtttctttaggcagagcctctgaactcagacgtgcagtacacggaagttcaagtgtcctcagctga gtctcacaaaggtaagtgccactcgagtgagtccccaggcattcgctttggcttgggtttaaaccccagtggtggcgggg gtgctgtgttcagtgagaagagtctgtgcaccctcagtcgctccaaaggaagtgattagcagacctaccggcctgctaag actggaaggagcaaggcccctggcctggcctgtctctgagctgtaaaatttcaataatttaaaagaaaaaaagaaaaggc caggcactgtggctcacacctgtaatcctagcactttgggaggccaaggcgggtggatcacctgagatca (SEQ ID NO:1214₃) tatattttatatattaatatataaatataaatacatatataatatataatatatgttttctttgtgtataatatatattt tataatattttatatatttttattttttatttttatatattttatatataatatttttatatttatattatttatatatt ttttattttatatata atatatatttttttttttctttgttgagacggagtctactctctgcccaggctggggtgcagt tgcgagatct (SEQ ID NO: 12144) tgcaaacctctgcctccgggttaaagcagcattctcctccctcagcctcccgagtagctgggattacaggcatgtcaccg ccacagccgggtaatttatttattttttttttgtatttttaagtagagatgggatttcaccatgttggccagcgtgaact cgaacttctgacttcaaaagatccacccccctcagcctcccaaagtgctgggattacaggtgtgag (SEQ ID NO: 12145) gaattcaatttgagttttccagacccgtcctcctccttggcagctaaggagcagtgtgggaagtcaggcctgagcctcag gtgttccctctctgccttcctgtgggtggagagccaggtattaccaggtacgaaaaggggctttgtgggtacaaggctca gtggtgagtacatttgacctggtcttgaccaagccagttccctgctctcaagacttcctcctcctatggaggaggggttg ggaaccacatccagctctgaccctagtggcaggcgaccaagtggtcacttggggtggaggaggggcaggaaggaactcag taaatcctggtttgctgcatgtttgctctgagactaattgctgggaaaaccccatgacgttggaagccatctccttctct gttatcacagagaaaaacagaagccaaaataaagccccatccggaaacatccctgacagcagagacaaagagcctgccag cctggtttactcattagcaagcagctgctccctggagtgggtggggaggagaggtagtgatgagctgcaactctgcctgc ccacccatcacttaactgggcagatttgggggcagctgcaactctagaagctccaccaagaagcagaaccccccaggccc aaacaccaagccctctccctccatttattcctcacctgccccagcccccactgtgggcctgggtgggagggtgagctggc cgtgaccaccccaccatgcgcctggtatatggtgtttgatagcatttgttgcagtgtctgcgttgtttgtgcacctgtct gcctcacagcctggagctcctgaaagctggggaccaggcccgatcacctttcctcttccacagtgcggggttcacactag gtgtctaggattctgctgagtgagtgatttggccaggcctgacatcaagcagagggtgtcttggggatgtggaggatccc ccaatagggttggggatccctacagcttcccttgagggccccacatctggtgccacagaaagagagtgaggggtgtgtgg gcatctctgctgtcccagcagtgtggtgccctggtagctcagccactctactgagttccaaatcctgtttgggtgccctg ggggaagtcagtgtaagggcctagtca (SEQ ID NO: 12146) aaggagggaaatccacttgaccatggcacaggaaccccccttacccaatctgggccttccctttcccccatctgtaaaag gagaacagtgcccacacgacatcagcctcttttcctacagtgagccttcctggccctttgtgcagtagacaggagctggg aagtgcccaggttccatcctgtttcctcagggttggtgggtatgtatgtgtgtgcacaccctgtgtgcatgagtgtgtgc acacccagattgcatgtttgtacatacagtgtgtatacaatgtgtgtagacacatcctatacactgtatgagggtataca tagcatgtatacacattgtgtgcatgagtgtgcgtgtgtatatgctgtgtgtgtatttttgtatacacatcctgtgccca taccccagtgtaaggtaaacagatggcaggaagggcgcccttgagtctcctccaggtatacgccacaccctgggtcagtc atcatgctgccatattgagagggtctagcccagaggatctcagccctgtctgcatattagggcccctgaggagatcctaa aaaaccagcaccagggacccccccagaccaatccaaccagaagctgcagtgaggcccaggagccagcagtgaaaacagcc agcccagctgtctatctctgtaagagttctcagtcccagctattcctagggtcactgacaacccccaggctctaacccag acctcaggatcttgttctggatcccggggtctgggctctcaggtgattgggaggccatagcccaaccctgcgttgaggga cctggcagaatgtctggacaagggtcacggtggcaggggaagaggagtgggggcagcaagctggaggctgcaggcccttg ctggggggctctccatccgtgggcccctcaggtccaggggttcctctggtgcatgtggccctgctccacaatggcctgct gacctcctattcccagactgggagtgacgctcgttagaccaagacctccttcttcttcttcttttttttttttgggaggt ggtgtgtcactgtgttgcccaggctggagtgcagtggcgcaatcttggctcactgcaacctctgcatcctgggttcaagc gattctcgtcccttagctctcgagtaactgggatcacagggacgcaccaccatgcccggttaattttttggaatttttag tagagacggggtttcggcatgttggccagaatggtctcaacctcctgacctcaagtgatcttgccccctcaacctcccaa agtgctgggattacaggtatgagccaccttgcccagccaggatcttctaacatcagaaatgacaaggtctctgggtgctt ctggacctggttctggtggggtgcagtggtggggtacagccttgcctgcagagcctcagaccttttcctatgactgcagt ggactgacctcgttcccagaggcagctactaacttatgcctggtcctttttccagatctaggaaagaaggacacagagac agtgtacagtgaagtccggaaagctgtccctggtgagtgagggtctccagtgccccagcctgggggatgccccctataat cactgatgggggcttgggagtgggcagagaaaagaagaagcaaagaagggcaaaaaaggggtggcacctcttacaccagc gctgtgggcttcctctctcccaccacccttaaaaagtcacctcgggtcacatttactattcatgtagtcaacgagcgctt cttgaatgcttactgaccccagccggtgacccttacctgctccccacacaggccctggtggctggggttccccaaggtct tggacgtcgagtgttttgctttggagacccccagtagcttcagcctttcttcttgttttcttttttctcttttttttttg gggatacggagtctcgctctgtcactcaggctggagtgcagtggtgcaatctcgactcactgcaacctccacttcccgga tttaagtgattctcctgcctcagcctcccaagtagatgggattacaggcgcctgtcaccacactcagctaattttttttt tttatatttgggagacagagtttcgctcttgatgcccaggctggggtgcaatggag (SEQ ID NO:12147) tgctgggattaccaagtgtgaccccccgccccagcagcttcagcttttctgacaagaagactgactttgggagtgggtgt gggtttgcggatctactctatttcctttggttcggctgcccccacttcgcttcccgtgacgacccactgcttactcatga aagggcttcccccagagctgagcacagagcttaagcagacccggaactgggggagctcaacaagtcctttttttcggtgg gggggtataataactgtattcaattcaggtgaaatgaaatacacaatgacaacttttaaattctgaaggtaagtcagcaa tccgaaagacgtaaacattgtgggggaaatagtgactgtgtgagtatctcgctttgtacagcagacctctatttaagtgg gttcttggaaagggaatcattaaaatggtccaggacatttctgcaaagggtgcctactcagcctaggcgtggtggctcat taagcactcagtaagtgctttatttatttaccccaaataaataaataaatataaaaggatgactcctccgagtacag cg ccaaaccagcagcagcaatctcgggcccagcccagacccacaaaactagtctctggaatctgaacttagccagcttcaga tgtttctgatgctgccaatatttgagaagcactgtttgtgttttgttttgtttttttgtttgaaacagagtctcactctg tcacccagactggagtacagcagtgccatctcagctgactgcaactccgtgcaacaccccccagcccctaaggcttaagc gatcctcccaagtagctagaaccacagacacacaccaccatgcccagctaagtttttgtatttttggtagagatgaggtt ttaccatgttgcccagactggtgttgaattcctgagctcaagcaatccacccccttcggcctcccaaagtgctgggatta caagcgtgagccactgtgccaggcaaaaagcactgttttagaagaaccatccaattctctgaggaccctgctttttatct gaaatagcgatcacttcttaattcacttttaaaagttggtatatctacaagaagaatagaaactcaacccttgtggaact tgaccctgaataatttttgaaaaaccaattctctggggaatttttagctcaaatacctcattt (SEQ ID NO: 12148) aaaaaaaaaaaaaaaaagaagaagtagtttctgcttttagtcagataaacaagctctggggagacttccttctacatctg aaccagctcaaaacaatccttatgccaaaggggcatattttgtggtggcatattctgatttccttcatctgctttagggc agctggctgttcaagtgggttctctcggggtctccaggttggttctaga (SEQ ID NO: 12149) ctttctttctttcctttcttttttttttttttgagacagggtcttcgctctgtcacccaggctggagtgcagtggcgcga tcgcagctcactgcaacctccagctcccgggttcaagtgattcttctgcctcagcctcctgagtagctgggaccacagct actgccaccacccccgggtaattttttttgtatttttagtagagacggtgtttcaccatattggtcaggctgatctcgaa ctccagacctcaggtgatccacctgccttggcctcccaaagtgctgggataacaggtgtgagacaccacgcccggccaga tcatat (SEQ ID NO: 12150) gatcctatctacgggaaacatgaagagtaatattctactgtggcctgggtgaccctgggcaagtcatagagcctctcaag accttggtcaccttctctgtgagatgaggtatgggctggaggcaggtcagtggtcctcgggctttattaaaacatcaata gtttggcgcaccccactccctgtgaatttcccattcactaggtctggagcggtgccgaaaacgtgcatttctaacaggtg tccacacgcagctgctcgccgacacgctggggcccgggctttgagaaccactcttgatgcagcatgttcctttctgattg tgccacgctaaggctctgcttcttgttggaaggagtagggtctttctcaccctccagaaatcctggagggatctttcagc attggtgggcaggtaaaacccagaaacactgtgcttattagagggaaggttgtattgagtgacccccaataaaacagggg gcccagggccgcgcgcagtggctcacgcctgtaatcccagcaatttgggaggctaaggcgggcggatcatgaggtcagga gatcgagaccatcctggctaacacggtggaaaccccatctctactaaaaatacaaaaaattagctggacgtggt (SEQ ID Nθ:12151) agataagcaatagggcatgggcaggcctgcctccaaggagcagccccagggccgaggagagagagctggcgctggcccag gggacttgagtttgatgggaaagcttgcagacagtgggggagctgcctggtctttccagtcttggcttttggctctaagc acagcttttttttttttttttttaattgttgtatcatgaggcgccttccactcagctgcctccccacgttaggggatgga cacagcactggcagggatcctgtgtgtctcagtttccctattgactctctgtggcctagagatgtatggtagaattccac actatgctttttttccaccgtgtttttttttttttttttttttgagacagggtctctctctgtcacccaggctggagtgc agtggcgcaatcttggctcactgcaacctccacctccccaggcaggcccctctgactcagctgggactacaggcatgcac caccagcacccagcaaaatatttttatattttagtagagatggggtttcgtcacattggccaggctggtcttgaactcca gagctcaagcaatccgcccgcctcagcctcccaaagtgctgggattacaatgcccagcccacttttttttttacttttta caattttattcttaaaattgtggtaaaacacatatcacataaaatttaccattttaactctaagtatccagctcagtggc actaagactacacttttggttgtcatagcgtggtgaacagagaagagaatgctactgcgtctcgtggagagaggccaggg gataccgctaaacatgcgacaatgcacaggacagtcccctccccaccacaaaacaccacccagcccaaaatttcaacagg gccaccatggagaaaccctggccagaggaattcacctcctgcaactcctccaacaggagagctggttttcctctccagta ccagcttgtggctgccctctgtcttgggagggtgacttaagggcacatcccacctgattactgtgggctctggatgggtg ctgagtcttggtctggggaacag (SEQ ID NO: 12152) aaattacccaggcatggtggtgtgcgcctgtagtcccaccaacttgggaggctgaggcaggagaattccttgaatctggg aggcggagggtgcagtgagccgagatagtgccagctgaggcaggagaattccctggaggtagaggttacggtgagccaag atggcgccaccacactccagcctgagtgacaaagcgagactctgtctcaaaaaaaaaaaaataaagaaaattttaaatga agtgccagggactttatgcgcatgtcatgtggagctagctacagggtcccggggaagctgtcttgcacaaaggagccata aacctctaagggcactgccggctgatgtctcctggctctcgcctcctccctcttttctcgacctgctcctgaccctgtga tgttgttggggcagttgaactgggttatttgcgttgctcactgccatgtcatcctttgttttgtagatgccgtggaaagc agatactctgtaagtacacatttcatatacattatatttaaaagtactccactgaacagtgaaatatttccagactcacc cacgcctgcattcacacgaattcttccccgctccctagcctgttcagaccagaagccctgggcttctctgactagccttg gccagttctgatttcgaatattctctcctgcaatttccatcattacatctcagcccacacgtgaagggattgggactctg gggtgcttagcgccaaacaagcaaagcacacatttcgtttaacgccaaagtctaggctctggaagtgaggcagatctagg gtgtatgcttggaggagtggagcagctgacagctcattgcaatttagccgatactaattaccccctacacaccaggccat cagctgcaggaggacacccaagcttcttgacctcagttcaccttctgatgagggaatcagacatgtgatcacttatcata aagccaagtgagctatgccagagcctatgggaacacagaacagagacctagctagtgccctcttccccaaggaatcattt ggaatggcccatgaagaatgaatggagtgatgatgccagcattgagggagaaagatcagcaggagcacaagggtgaggga tgaccagtttcaagcagtgtgggatgggaaagaagagtgtgacagtgacaagtgacgggagaaagataagtcagggctta aatccaaaggatttacatcccttgttaagaagcttcattctgtaggaaatggagttaggaatctgcatttggcagatggg agggtttatgaaagacacagaggcccacgttcaacttttgcaaagacgtgtcttccaatcccaacctttttgtgagctac ccagcaatgcaggagttaactgggcagctaatatctgaagaaatgaggcatttgccgcataaacttcttttaggtctggg aagaactttcagcaaagatttcaggtagctcttccagtggcccctggcttcctttgttttgcccatgtcaggactcttgt aaaacagagctc (SEQ ID NO: 12153) gagctccagctttccagctgtcttttgggtgagcctgtcttcctcaagctcaagcttccttatctataaagtggagatgg tgatgacaatgatgataagagcaacctattaggattttaaggatgaaatgagcaactgcaaccaccatataaaagctgca agctgcaaaccaccatataaaagctggttgatctcaagctcttttcatcacttgggcaatagtaggtgtggatgggggac ttaacttgatttggccatgaaatgaccctgccacatatggagaatgtagcagttgcttacccaaggcataggattcaacc aaggccaggctttgacttaggaatcagagacccacattaacatttgacttcccgcttcttagccatgtcaccatgggcaa atttcttggcctctcaagacctctgcttcctaatctgtaaactgggaatcataaactccctcacttggttgttgcaaggg ttgaatgagcac (SEQ ID NO: 12154) ctatcaatctccagagctttttctttttaagtgtgagcgagtttattagagaagtaaagagacccaagagtgcctactcc atagacagagcagccactgtgacactgtacccattaaacactaactctccattgcccctccagcaacccctagcacccac tgtctactttctgtctctatgtggttgtctatttgagggacatcacataagtggagtcatatatttgtcctttcatgtct cccttatttcatttagcataacgttttcaagggtttcctgtgttgtgaatatatcagaatttcattctctttttaaggta gaatcatatcattttaaaacatttcagttggaccatctaagttcagtccttcattttcaacaattaaaaaacagccctca accgggtgcatctcacgttagctagagacagaactggagctagaagtcagatctcttaccaaagttgcctttcttcttct gtgggtaagtggggcacccttgggacgctgtgctgggcgtacatgggtgcttgatgaagttacttggtggactgatgtga ttgatgtccaacatgtatgcagggacagaggctatggtccctacagagcaggcatggagagaaggagaaatacatacggg caggagccaggagagggagggtgtagtgagcagagaccgcgccactgcactccagcctgagtgacagagtgagaatccat ctaaaaaattgcttactaaagaagtggtctcctgaggtcttaagacgttcctggcaatgtcttgagtgggtgggagagag cctccagtcattgagctgtggaatttcagaggtgagaaccacacctaacccccaattactttcccctgtttgcctcagtg acacagctgcaggaaccctggtgggtgttgtattaagtaaatttgacctttattctttgcagatctgtgaaatgttgtct tctgaggggccacgtgtatctgtagtgctgaggactccttggggcctctgaagtcacagagagaacctgcagggtggggg accagtgtgtgacagccctgctttgcattttctttgagaagtgctgtcattttgcatttctctccaccaggggaatcttc aatcttgagaggtgtga cataacttgccttgtttcttgtcgctacagagaacggaaggctcccttgatggaacttagac agcaaggccagatgcacatccctggaaggacatccatgttccgagaagaacagatgatccctgtatttcaagacctctgt gcacttatttatgaacctgccctgctcccacagaacacagcaattcctcaggctaagctgccggttcttaaatccatcct gctaagttaatgttgggtagaaagagatacagaggggctgttgaatttcccacataccctccttccaccaagttggaaca ^' tccttggaaattgggaagagcacaagaggagatccagggcaaggccattgggatattctgaaacttgaatattttgtttt gtgcagagataaagaccttttccatgcaccctcatacacagaaaccaattttcttttttatactcaatcatttctagcgc atggcctggttagaggctggttttttctcttttcctttggtccttcaaaggcttgtagttttgggtagtccttgttcttt ggaaatacacagtgctgaccagacagcctccccctgtcccctctatgacctcgccctccacaaatgggaaaaccagacta cttgggagcaccgcctgtgaaataccaacctgaagacacggttcattcaggcaacgcacaaaacagaaaatgaaggtgga acaagcacatatgttcttcaactgtttttgtctacactctttctcttttcctctacatgctgaaggctgaaagacaggaa agatggtgccatcagcaaatattattcttaattgaaaacttgaaatgtgtatgtttcttactaatttttaaaaatgtatt ccttgccagggcaggcaaggtcgtcacgcctgtaatcccagcacttcaggaggctgaggtgggcggatc (SEQ ID NO: 12155) gaattccgggagaagtgaccagagcaatttctgcttttcacagggcgggtttctcaacggtgacttgtgggcagtgcctt ctgctgagcgagtcatggcccgaaggcagaactaactgtgcctgcagtcttcactctcaggatgcagccgaggtgggccc aaggggccacgatgtggcttggagtcctgctgacccttctgctctgttcaagccttgagggtcaagaaaactctttcaca atcaacagtgttgacatgaagagcctgccggactggacggtgcaaaatgggaagaacctgaccctgcagtgcttcgcgga tgtcagcaccacctctcacgtcaagcctcagcaccagatgctgttctataaggatgacgtgctgttttacaacatctcct ccatgaagagcacagagagttattttattcctgaagtccggatctatgactcagggacatataaatgtactgtgattgtg aacaacaaagagaaaaccactgcagagtaccagctgttggtggaaggagtgcccagtcccagggtgacactggacaagaa agaggccatccaaggtgggatcgtgagggtcaactgttctgtcccagaggaaaaggccccaatacacttcacaattgaaa aacttgaactaaatgaaaaaatggtcaagctgaaaagagagaagaattctcgagaccagaattttgtgatactggaattc cccgttgaggaacaggaccgcgttttatccttccgatgtcaagctaggatcatttctgggatccatatgcagacctcaga atctaccaagagtgaactggtcaccgtgacggaatccttctctacacccaagttccacatcagccccaccggaatgatca tggaaggagctcagctccacattaagtgcaccattcaagtgactcacctggcccaggagtttccagaaatcataattcag aaggacaaggcgattgtggcccacaacagacatggcaacaaggctgtgtactcagtcatggccatggtggagcacagtgg caactacacgtgcaaagtggagtccagccgcatatccaaggtcagcagcatcgtggtcaacataacagaactattttcca agcccgaactggaatcttccttcacacatctggaccaaggtgaaagactgaacctgtcctgctccatcccaggagcacct ccagccaacttcaccatccagaaggaagatacgattgtgtcacagactcaagatttcaccaagatagcctcaaagtcgga cagtgggacgtatatctgcactgcaggtattgaca'aagtggtcaagaaaagcaacacagtccagatagtcgtatgtgaaa tgctctcccagcccaggatttcttatgatgcccagtttgaggtcataaaaggacagaccatcgaagtccgttgcgaatcg atcagtggaactttgcctatttcttaccaacttttaaaaacaagtaaagttttggagaatagtaccaagaactcaaatga tcctgcggtattcaaagacaaccccactgaagacgtcgaataccagtgtgttgcagataattgccattcccatgccaaaa tgttaagtgaggttctgagggtgaaggtgatagccccggtggatgaggtccagatttctatcctgtcaagtaaggtggtg gagtctggagaggacattgtgctgcaatgtgctgtgaatgaaggatctggtcccatcacctataagttttacagagaaaa agagggcaaacccttctatcaaatgacctcaaatgccacccaggcattttggaccaagcagaaggctagcaaggaacagg agggagagtattactgcacagccttcaacagagccaaccacgcctccagtgtccccagaagcaaaatactgacagtcaga gtcattcttgccccatggaagaaaggacttattgcagtggttatcatcggagtgatcattgctctcttgatcattgcggc caaatgttattttctgaggaaagccaaggccaagcagatgccagtggaaatgtccaggccagcagtaccacttctgaact ccaacaacgagaaaatgtcagatcccaatatggaagctaacagtcattacggtcacaatgacgatgtcagaaaccatgca atgaaaccaataaatgataataaagagcctctgaactcagacgtgcagtacacggaagttcaagtgtcctcagctgagtc tcacaaagatctaggaaagaaggacacagagacagtgtacagtgaagtccggaaagctgtccctgatgccgtggaaagca gatactctagaacggaaggctcccttgatggaacttagacagcaaggccagatgcacatccctggaaggacatccatgtt ccgagaagaacagataatccctgtatttcaagacctctgtgcacttatttatgaacctgccctgctcccacagaacacag caattcctcaggctaagctgccggttcttaaatccatcctgctaagttaatgttgggtagaaagagatacagagggg (SEQ ID NO: 12156) gaccagagcaatttctgcttttcacagggcgggtttctcaacggtgacttgtgggcagtgccttctgctgagcgagtcat ggcccgaaggcagaactaactgtgcctgcagtcttcactctcaggatgcagccgaggtgggcccaaggggccacgatgtg gcttggagtcctgctgacccttctgctctgttcaagccttgagggtcaagaaaactctttcacaatcaacagtgttgaca tgaagagcctgccggactggacggtgcaaaatgggaagaacctgaccctgcagtgcttcgcggatgtcagcaccacctct cacgtcaagcctcagcaccagatgctgttctataaggatgacgtgctgttttacaacatctcctccatgaagagcacaga gagttattttattcctgaagtccggatctatgactcagggacatataaatgtactgtgattgtgaacaacaaagagaaaa ccactgcagagtaccaggtgttggtggaaggagtgcccagtcccagggtgacactggacaagaaagaggccatccaaggt gggatcgtgagggtcaactgttctgtcccagaggaaaaggccccaatacacttcacaattgaaaaacttgaactaaatga aaaaatggtcaagctgaaaagagagaagaattctcgagaccagaattttgtgatactggaattccccgttgaggaacagg accgcgttttatccttccgatgtcaagctaggatcatttctgggatccatatgcagacctcagaatctaccaagagtgaa ctggtcaccgtgacggaatccttctctacacccaagttccacatcagccccaccggaatgatcatggaaggagctcagct ccacattaagtgcaccattcaagtgactcacctggcccaggagtttccagaaatcataattcagaaggacaaggcgattg tggcccacaacagacatggcaacaaggctgtgtactcagtcatggccatggtggagcacagtggcaactacacgtgcaaa gtggagtccagccgcatatccaaggtcagcagcatcgtggtcaacataacagaactattttccaagcccgaactggaatc ttccttcacacatctggaccaaggtgaaagactgaacctgtcctgctccatcccaggagcacctccagccaacttcaeca tccagaaggaagatacgattgtgtcacagactcaagatttcaccaagatagcctcaaagtcggacagtgggacgtatatc tgcactgcaggtattgacaaagtggtcaagaaaagcaacacagtccagatagtcgtatgtgaaatgctctcccagcccag gatttcttatgatgcccagtttgaggtcataaaaggacagaceatcgaagtccgttgcgaatcgatcagtggaactttgc ctatttcttaccaacttttaaaaacaagtaaagttttggagaatagtaccaagaactcaaatgatcctgcggtattcaaa gacaaccccactgaagacgtcgaataccagtgtgttgcagataattgccattcccacgccaaaatgttaagtgaggttct gagggtgaaggtgatagccccggtggatgaggtccagatttctatcctgtcaagtaaggtggtggagtctggagaggaca ttgtgctgcaatgtgctgtgaatgaaggatctggtcccatcacctataagttttacagagaaaaagagggcaaacccttc tatcaaatgacctcaaatgccacccaggcattttggaccaagcagaaggctaacaaggaacaggagggagagtattactg cacagccttcaacagagccaaccacgcctccagtgtccccagaagcaaaatactgacagtcagagtcattcttgccccat ggaagaaaggacttattgcagtggttatcatcggagtgatcattgctctcttgatcattgcggccaaatgttattttctg aggaaagccaaggccaagcagatgccagtggaaatgtccaggccagcagtaccacttctgaactccaacaacgagaaaat gtcagatcccaatatggaagctaacagtcattacggtcacaatgacgatgtcggaaaccatgcaatgaaaccaataaatg ataataaagagcctctgaactcagacgtgcagtacacggaagttcaagtgtcctcagctgagtctcacaaagatctagga aagaaggacacagagacagtgtacagtgaagtccggaaagctgtccctgatgccgtggaaagcagatactctagaacgga aggctcccttgatggaacttagacagcaaggccagatgcacatccctggaaggacatccatgttccgagaagaacagatg atccctgtatttcaagacctctgtccgaattccgggagaagtgaccagagcaatttctgcttttcacagggcgggtttct caacggtgacttgtgggcagtgccttctgctgagcgagtcatggcccgaaggcagaactaactgtgcctgcagtcttcac tctcaggatgcagccgaggtgggcccaaggggccacgatgtggcttggagtcctgctgacccttctgctctgttcaagcc ttgagggtcaagaaaactctttcacaatcaacagtgttgacatgaagagcctgccggactggacggtgcaaaatgggaag aacctgaccctgcagtgcttcgcggatgtcagcaccacctctcacgtcaagcctcagcaccagatgctgttctataagga tgacgtgctgttttacaacatctcctccatgaagagcacagagagttattttattcctgaagtccggatctatgactcag ggacatataaatgtactgtgattgtgaacaacaaagagaaaaccactgcagagtaccagctgttggtggaaggagtgccc agtcccagggtgacactggacaagaaagaggccatccaaggtgggatcgtgagggtcaactgttctgtcccagaggaaaa ggccccaatacacttcacaattgaaaaacttgaactaaatgaaaaaatggtcaagctgaaaagagagaagaattctcgag accagaattttgtgatactggaattccccgttgaggaacaggaccgcgttttatccttccgatgtcaagctaggatcatt tctgggatccatatgcagacctcagaatctaccaagagtgaactggtcaccgtgacggaatccttctctacacccaagtt ccacatcagccccaccggaatgatcatggaaggagctcagctccacattaagtgcaccattcaagtgactcacctggccc aggagtttccagaaatcataattcagaaggacaaggcgattgtggcccacaacagacatggcaacaaggctgtgtactca gtcatggccatggtggagcacagtggcaactacacgtgcaaagtggagtccagccgcatatccaaggtcagcagcatcgt ggtcaacataacagaactattttccaagcccgaactggaatcttccttcacacatctggaccaaggtgaaagactgaacc tgtcctgctccatcccaggagcacctccagccaacttcaccatccagaaggaagatacgattgtgtcacagactcaagat ttcaccaagatagcctcaaagtcggacagtgggacgtatatctgcactgcaggtattgacaaagtggtcaagaaaagcaa cacagtccagatagtcgtatgtgaaatgctctcccagcccaggatttcttatgatgcccagtttgaggtcataaaaggac agaccatcgaagtccgttgcgaatcgatcagtggaactttgcctatttcttaccaacttttaaaaacaagtaaagttttg gagaatagtaccaagaactcaaatgatcctgcggtattcaaagacaaccccactgaagacgtcgaataccagtgtgttgc agataattgccattcccatgccaaaatgttaagtgaggttctgagggtgaaggtgatagccccggtggatgaggtccaga tttctatcctgtcaagtaaggtggtggagtctggagaggacattgtgctgcaatgtgctgtgaatgaaggatctggtccc atcacctataagttttacagagaaaaagagggcaaacccttctatcaaatgacctcaaatgccacccaggcattttggac caagcagaaggctagcaaggaacaggagggagagtattactgcacagccttcaacagagccaaccacgcctccagtgtcc ccagaagcaaaatactgacagtcagagtcattcttgccccatggaagaaaggacttattgcagtggttatcatcggagtg atcattgctctcttgatcattgcggccaaatgttattttctgaggaaagccaaggccaagcagatgccagtggaaatgtc caggccagcagtaccacttctgaactccaacaacgagaaaatgtcagatcccaatatggaagctaacagtcattacggtc acaatgacgatgtcagaaaccatgcaatgaaaccaataaatgataataaagagcctctgaactcagacgtgcagtacacg gaagttcaagtgtcctcagctgagtctcacaaagatctaggaaagaaggacacagagacagtgtacagtgaagtccggaa agctgtccctgatgccgtggaaagcagatactctagaacggaaggctcccttgatggaacttagacagcaaggccagatg cacatccctggaaggacatccatgttccgagaagaacagataatccctgtatttcaagacctctgtgcacttatttatga acctgccctgctcccacagaacacagcaattcctcaggctaagctgccggttcttaaatccatcctgctaagttaatgtt gggtagaaagagatacagaggggcccgggttcaagcgattctcctgcctcagcctcttgggtagctgggattataggcgt gtgccaccgtgcctggctaatttttgtatttttattggagacagggtttcaccatgttggccaggctggtctgaaactcc tgacctcaggcaatcctcctacctcagcctctcaaagtgctgggattaccggcatgagccacgactcccggccccaaagg tcaatcttaaagctacaaggtatcttttaaaaggagtaggaataacgtattttgaggcttaaaggagtaggaatagtgta tttttagatttgaagccatcttctaaagggtacgatatttggttaacatgtcactccttatcgccatggaagaagttaat tctattcttttttttttttttttgagatggagtctcactctgttgcccaggctggagtacaatggtgtgatctcagctca ctgcaacctctgcctcctgggttcaagcaattctcctgcctcagcctcctgagtagcagggattacaggggttctccacc atgcctgtctaatttttgtatttttttttttagtagaggtggagtttcaccatgttggtcaggctggtctcaaaccccta acctcatgatccgcccgccttggcctcccaaagtgctgggattacaggcgtgagccaccatgcccagccgttaattctat tcttactgcttactcccttattttgtatgttcttcttctatcttacatcttttgcttttgctattgcttaagctagccta cgccaagggtgctctttgccccctacttcctctgctattctcgcctcagttccgctgcattccaagctcagcctgcccca gcagcaggtctctttgacaaacctgcaattttggggaaaagtcagccccaagaaaggcagggggcccagacttatgctgt gtggcaaaagccctctttgatgggggaaggggaggactggaaaagcagagagatctttctggatgtcctgggagagcagc cctttgggtggtgggtggaggctggaggcagggaggaatcccctcacagtgccatgagaagggcccccaaacccaggcga gacagagggagggtcaagaacgccaaggcaaatgtcacttgtgccttgttttttccctaaagaaactaaacaaagcggcc gcgttcggtggcccctcaggaaggccggtcatttcctgaggagatatcaggccagcccaggccccattgttcccggtttc cagccatggctgccattacctgaccagcgccacagccggtctctctgcaggqgccgggagaagtgaccagagcaatttct gcttttcacagggcgggtttctcaacggtgacttgtgggcagtgccttctgctgagcgagtcatggcccgaaggcagaac taactgtgcctgcagtcttcactctcaggatgcagccgaggtgggcccaaggggccacgatgtggcttggagtcctgctg acccttctgctctgtgagtgtttactctgtttccacatcactttaactccatgagcatcgaaggaattccgggagaagtg accagagcaatttctgcttttcacagggcgggtttctcaacggtgacttgtgggcagtgccttctgctgagcgagtcatg gcccgaaggcagaactaactgtgcctgcagtcttcactctcaggatgcagccgaggtgggcccaaggggccacgatgtgg cttggagtcctgctgacccttctgctctgttcaagccttgagggtcaagaaaactctttcacaatcaacagtgttgacat gaagagcctgccggactggacggtgcaaaatgggaagaacctgaccctgcagtgcttcgcggatgtcagcaccacctctc acgtcaagcctcagcaccagatgctgttctataaggatgacgtgctgttttacaacatctcctccatgaagagcacagag agttattttattcctgaagtccggatctatgactcagggacatataaatgtactgtgattgtgaacaacaaagagaaaac cactgcagagtaccagctgttggtggaaggagtgcccagtcccagggtgacactggacaagaaagaggccatccaaggtg ggatcgtgagggtcaactgttctgtcccagaggaaaaggccccaatacacttcacaattgaaaaacttgaactaaatgaa aaaatggtcaagctgaaaagagagaagaattctcgagaccagaattttgtgatactggaattccccgttgaggaacagga ccgcgttttatccttccgatgtcaagctaggatcatttctgggatccatatgcagacctcagaatctaccaagagtgaac tggtcaccgtgacggaatccttctctacacccaagttccacatcagccccaccggaatgatcatggaaggagctcagctc cacattaagtgcaccattcaagtgactcacctggcccaggagtttccagaaatcataattcagaaggacaaggcgattgt ggcccacaacagacatggcaacaaggctgtgtactcagtcatggccatggtggagcacagtggcaactacacgtgcaaag tggagtccagccgcatatccaaggtcagcagcatcgtggtcaacataacagaactattttccaagcccgaactggaatct tccttcacacatctggaccaaggtgaaagactgaacctgtcctgctccatcccaggagcacctccagccaacttcaccat ccagaaggaagatacgattgtgtcacagactcaagatttcaccaagatagcctcaaagtcggacagtgggacgtatatct gcactgcaggtattgacaaagtggtcaagaaaagcaacacagtccagatagtcgtatgtgaaatgctctcccagcccagg atttcttatgatgcccagtttgaggtcataaaaggacagaccatcgaagtccgttgcgaatcgatcagtggaactttgcc tatttcttaccaacttttaaaaacaagtaaagttttggagaatagtaccaagaactcaaatgatcctgcggtattcaaag acaaccccactgaagacgtcgaataccagtgtgttgcagataattgccattcccatgccaaaatgttaagtgaggttctg agggtgaaggtgatagccccggtggatgaggtccagatttctatcctgtcaagtaaggtggtggagtctggagaggacat tgtgctgcaatgtgctgtgaatgaaggatctggtcccatcacctataagttttacagagaaaaagagggcaaacccttct atcaaatgacctcaaatgccacccaggcattttggaccaagcagaaggctagcaaggaacaggagggagagtattactgc acagccttcaacagagccaaccacgcctccagtgtccccagaagcaaaatactgacagtcagagtcattcttgccccatg gaagaaaggacttattgcagtggttatcatcggagtgatcattgctctcttgatcattgcggccaaatgttattttctga ggaaagccaaggccaagcagatgccagtggaaatgtccaggccagcagtaccacttctgaactccaacaacgagaaaatg tcagatcccaatatggaagctaacagtcattacggtcacaatgacgatgtcagaaaccatgcaatgaaaccaataaatga taataaagagcctctgaactcagacgtgcagtacacggaagttcaagtgtcctcagctgagtctcacaaagatctaggaa agaaggacacagagacagtgtacagtgaagtccggaaagctgtccctgatgccgtggaaagcagatactctagaacggaa ggctcccttgatggaacttagacagcaaggccagatgcacatccctggaaggacatccatgttccgagaagaacagataa tccctgtatttcaagacctctgtgcacttatttatgaacctgccctgctcccacagaacacagcaattcctcaggctaag ctgccggttcttaaatccatcctgctaagttaatgttgggtagaaagagatacagaggggtcttttggttttgctattgc ttaagctagcctacgccaagggtgctctttgccccctacttcctctgctattctcgcctcagttccgctgcattccaagc tcagcctgccccagcagcaggtctctttgacaaacctgcaattttggggaaaagtcagcccaagaaaggcagggggccca gacttatgctgtgtggcaaaagccctctttgatggggcaagggtaggactggaaaagcagagagatctttctggatgtcc tgggagagcagccctttgggtggtgggtggaggctggaggcagggaggaatcccctcacagtgagaagggcccccaaacc caggcgagacagagggagggtcaagaacgccaaggcaaatgtcacttgtgccttgttttttccctaaagaaactaaacaa agcggccgcgttcggtggcccctcaggaaggccggtcatttcctgaggagatatcaggccagcccaggccccattgttcc cggtttccagccatggctgccattacctgaccagcgccacagccggtctctctgcaggcgccgggagaagtgaccagagc aatttctgcttttcacagggcgggtttctcaacggtgacttgtgggcagtgccttctgctgagcgagtcatggcccgaag gcagaactaactgtgcctgcagtcttcactctcaggatgcagccgaggtgggcccaaggggccacgatgtggcttggagt cctgctgacccttctgctctgtgagtgtttactctgtttccacatcactttaactccatgagcatcgaagcttctggaat caacatgtttcttatgtttcttgcaggttcaagccttgagggtcaagaaaactgtaagtctgatgtttccactgtaacag atgtttctacctggcttcctcctttctcttctgtgatgcctaaaacgcacattaaattgctggggtttgatacttctaac aattaaggaaaagaatccaattgagaactaaagtttatcccatgtgggcatttttagaaaggcttagatctaagccaagt tctggtcagtgtgttttagaagtagcacacgtttccttggctggtctgaaagtagtgggttatcttgatgaattgtttag tcagttacagatcaaactccatgttcttttctctgttctcacgactactcttgactagtctaaaaatatattaggttgtt gaaaagtaattgtggtttttgccattactttttaaaagatggcaaaaaacacaattataagtagcacacattttcttttt tttttccttttttttttgagacagagtctctgttacccaggctggagtgcagtggtgcaatccggctctctgcaaactcc gcctccagggttcaagggattctcctgtctcagcctcctgggtcgctggaattagaggttggcaggctggtctcaaactc ctgacctcaggtgatccgctggcctccacctcccaaagtgctgggattacaggtgtgagccaccacgcccggcctcacat tttctagatttcagtgcattgctgttttttgggatggggaagtgatttttttattttaatgagcaattccataattagtt ttttgttgttttaccataatggcttatttgaatattgtaaggtatccccaactgtttttatttgcaaatgagatataatt gatttgttagacatatgaagacagatcctagtttaaattgttgctactttttttactcctaaatgataaaaatcacacac tcgagctcgctgtcccacagcccacccttcatcacaatagtcctgaaactttttgggttcagtaaggaaatctgtgggcc ttctctccagaaaaagcacacatttgcacacaattggaggtagttgatgagcctcctaacacccacccatgcacctccca ggggctgtgtcccccaggttgtgaacagtcactctgtgtaaatagtgagacctacaggcagtaattcagtttggctgtgc ttggctggtttatttagaaagatgataatgtttgagctctccaagggcagacactgccagcctcactgttctctgaaccc ccagtatgggacagtgcttggcacagaaaaacccccttaaatgtttgctatgaatggtgctaaggaagaaggcagagaat gtcaaccagaggccaggcactggcaatatatacacggccccataccttggctcactgcaacctctgcctcccaggttcaa gcagttctcctgcctcagtctcccaagtagctgggattacaggcgcccaccaccacacccggctaattttgtatttttag tagagatgaggtttcaccatgttggccaggctggtcttgaactcctgacctcaagtgatccacccgcctcggcctcccaa agtgctgggattacaggcataaaccaccgtgcccggctggtccagagctcatccagcaggcttcttaaatcaggagcttg taagttgcatataaagacaaaaaagggagttccaaagagtaatgctgtgggaaatgacttgaatttaaaccgtcaccttg tttgatctcatggactggtcagacaccatttttgttgtcgttgttgttgttaaattaattgctcagaatatagcagcagg cgcaaattgtagtactcgttttaaaattgaagattaaattttaaattacccaacaaaggcctaactttgttaaaaggaat tctaccgacagcctatggttactggatataagccaattctgttctggggacttgccagaaatgacacaattggccagttg acccacagcctagttcctagcagagattggatagctgattgagcgttgtggctgttttgaggcttgaccagagattcctg ccgttggcagaggggaatctgtagtctttgcttcttggtagcaggtgaggctgaaaacgcaagtagcaggctaaaaactg gtttcaagtcctcaccatctggtgaaacctcagagcccatcagatagaaaatgccagctgggactgtgctaattcggtaa ggcctgggtggagaaggagggcctgggcacgaccatctggtttcggaatggaggtagcagtcatttattaagtacttaat gtatatcgggcactgtacaggagacgttctggctgttctcctgtacatttcctgcaaagacctaatgagatatgattact ccatcctacaggtaaggaaactgagctcagagagtctagctgcccagggtcacacagtaaatgatgagccaggacttgaa cacttgactgcttgaatcctgtactccctccaggggccaagatgtggcagctcacagaatgcctatatcttttttttttt ttgtcttttgagacagtctcactctgttgcccaggctggagtgcagtggtgagatctcacctcactgcaacccccgcctc ccaggttcaagtgattcttgtgcctcagcctctcaagtagctgggttacaggcctgcaccaccaaacctggctaattttt gtatttttagtagagagggggtttcaccatgttggccaggccagtctctaactgctgacctcaggtgatccacccacctt ggtctcccaaagtgctgggattataggcgtgagccaccatacctagctctacatctttatcactctgttcctttgccttg gtgggaaaagttgcagcttagtaccaactgcctcctgcttgagccactgtgcacagttactatcagcctggccctgtagg cacgtagaacccctggactcaatactgcataggatgggataagaccacatctgatgtggtgaaggtcaccgggatgatgt tgtttctgagataacaggtatgtctgccttccttcgggttgcatttagctttcacaatcaacagtgttgacatgaagagc ctgccggactggacggtgcaaaatgggaagaacctgaccctgcagtgcttcgcggatgtcagcaccacctctcacgtcaa gcctcagcaccagatgctgttctataaggatgacgtgctgttttacaacatctcctccatgaagagcacagagagttatt ttattcctgaagtccggatctatgactcagggacatataaatgtactgtgattgtgaacaacaaagagaaaaccactgca gagtaccagctgttggtggaaggtgagtccttggaactgagcacaggcaagcagatggagcatagcacacagtggcgtga ataacagctgtgaatgaatagtgacactggacttaactctccacccatcaccctctcattcatctgcctggcattttcct tacctgaatacgtaagcactagacatattccccaataggcaggcccttccttccttccttccttccttccttccttcctt ccttccttccttccttccttccttccttcctttctttctttgatggagtctcactctgtcacccagtctggagtgcagtg ggtgatctcggctcactgcaacctctgcctcccaggttcaagcgattctcctgcctcagcctcccaagtaattgggatta caggtgtgtgccaccacacctggctaattttgtatttttagtagagatggggtttcactgtgttggtcaggctggtctcg aactctgacctcaagtgatccacctgcctcccaaaatgcttcttcatctcgctctataaattacaatttctttcttcaag actcaactcaatgatgttttgccaaaacaaaatgggtctaccccagggtgccagtcagtacagctctgatgctctctcta caggcaatggtatttgtgtgtataaaggccacagcggtgtgttaagacacctcgttctgcagtcactctgcctgggtttc aatcttgggtcaagtccttaacatgctctaaacttcaaaatcctcaccagtaaaaggaagataacaacgatacccatttc aggcaattattgagagggttaaaagtgtcatgtgggtagagtgcttagcaaaatttccagcacctagtgagttcctaata aatagaaatgtatttatttatttgagacagagtcttcctctgtcacccaggctaaagagcaatggcgcgaccttggctca ctgcaacctctgtctcctgggttcaagcgattctcctgtctcagcctcccaagaaactgggattacaggcacgcgccact gtgcctggctaattttttgtatttttagtaaggatggggttttaccatgttggccagcctggtctcgaactcctaacttc aagtgatttacccaccttggcctcccagagtgtcaggattacaggtgtgagccaccatgcccggtccacaaatattctat ttcactcagtattggcatccgttcttacacatctgtctgctcttctggatagtgaaattgtaaagacagagatggtgttt gggtttattcttatatcttgaacaatgaatctggc catagtaggcattcagtcaatgttcatggaataaattaaagtca gtcctagcctgtgggtgcattcaataaagggtaacaacaatcacagtgacactgacaaatactgggttacctttcccctc taagcatcatctgttgggaatctgattgtgtcctcttcccaataggattataaaccattgaaaacaccaagtacatcttg accatattttattttttaaatttatttatttatttatttatttatttttagacagagtctcactctgttgcccaggctgg agggcagtggcacgatctcagctcactgcaacctctgccttcggggttcaagcaattctcctgcctcagcctccaagtag ctgggattacaggtgcctgccaccatgccggctaattttgatttaatagagatggggttcgccatgttggccaggctggt ctcaaactcctgacctcaggtgatccacctgcctcagcctcccaaagtgttgagattacagatgtgagccacctcgcgtg gccttagtggtgattttggtggacccatcacccgagcagtgtacactgtacccagtgtgtagtcattttatccctcgctc cctcccactctttcccctgagtccccaaagtccactgtatcattcttatgcctttgtttcctcatagcttagctcccatt gagcatattttatattttttcctttcttttcttctcttttttgagacagggtctctgttgcccaggctggagtgcagtgg tgggattactgctcactgccgcctcaacctcctaggctcaagtgattctcccacctcggcctcccaagtagctgggacta ccagtgcacaccactaactacccctggctaattttaatttttttttttgtagagatagcatttcaccgtgttgcccaggc tggtctccaactcctgggctcaagagatccacccacctcagcctccagattttatatatttcaaagtgcctagtactgtg ctgggcacatacctgttcatttattacctggtaggtcgcactgggtgttcagagaacaaaaaagagccctctcatgggat caactacagtcactcagcggaggggagggcttgtgtctctcaatcaggctgatactgacagactttcttcttcaatcagg ctgatactgacatgactttctactttccccgtaggagtgcccagtcccagggtgacactggacaagaaagaggccatcca aggtgggatcgtgagggtcaactgttctgtcccagaggaaaaggccccaatacacttcacaattgaaaaacttgaactaa atgaaaaaatggtcaagctgaaaagagagaagaattctcgagaccagaattttgtgatactggaattccccgttgaggaa caggaccgcgttttatccttccgatgtcaagctaggatcatttctgggatccatatgcagacctcagaatctaccaagag tgaactggtcaccgtgacgggtcagcatctgctcccttcctcatcgttctttgtggtttctggtgttctagagaagaaag gttgaattttaaagttagttaggaacaatagaaaagtttgaaaaggggaagcagcaaaaagagcagaagaggctcctctt gcccaggtttgcacctgagtccaaccaggttgtcttcctctcttgcagaatccttctctacacccaagttccaca cagc cccaccggaatgatcatggaaggagctcagctccacattaagtgcaccattcaagtgactcacctggcccaggagtttcc agaaatcataattcagaaggacaaggcgattgtggcccacaacagacatggcaacaaggctgtgtactcagtcatggcca tggtggagcacagtggcaactacacgtgcaaagtggagtccagccgcatatccaaggtcagcagcatcgtggtcaacata acaggtagggctgctgctgccggagggtgttggcatatggcgggctcaagaggccaccatgctgcaatccagcatggcca aagagagctgatcatttcctgcccctgcttatctgaatgaatgtgctcagatggggctttggtgctcgtgggaggaaacc actgcagagcgagttaacagtctactgtgcgtgttgagggtacaggctccggcaccaaagcttaaccctgccgctcactg cttctgtgaccttgggtgagttattgaacgtgccgcagcgctgtgagatggtgataatgaccttttaggactgctataat gattaatgagataactatactgtaagcatgagctgagagatttgtacagagtaagactctgaaacactggttaatgtttt cattactctgttatatttctccatcccctgtgacaagcactatgctagatcgaattccggcctgtgaatccatctggttc ttggactttttttggttggtaagctattgattattgccacaatttcagatcccgttattggtctattcagagattcaact tcttcctggtttagtcttgggagagtgtgtgtgttgaggaatttatccatttctcctagattttctagtttatttgcgta gaggtgtttgtagatattctctgatggtagtttgtatttgtgtgggatcggtgatgatatcccctttatcattttttatt gcgtgtatttgattcttctctctttttttctttattaggcttgctagcggtctatcaattttgttgatcctttcaaaaaa ccagctcctggattcattaattttttgaagggttttttgtgtctctatttccttcagttctgctctgattttagttattt cttgccttctgctagcttaaggagtttcattcttgttgcccaggctggagtgcagtggagcaatctcggctcactgcaat ctctgtctcctgggttcaagggattctcttgcctcagcctcccgagtatctgggattacaggcgcccaccaccatgctgg ctaattttatatttttagtagagatggggtttcaccatgttgcccaggctggtctcaactcctgacctcaggtgatccac ccacctctgcctcccaaagtgctgggattacaggcatgagccaccacacctggccacaagttgcaaaacttttctaatcc ttgtcattgaaataaattggattaacaagaaaggaaaacctgccattggaatcctaggcaaagaatgaaccctagctcct tactggggtgatcgttaggtacatgagaagcaaaggaaaactttttgctggaagttggaagttggttctgccaagagcac ctgagccaagggcctctccaggaagggtctttagggtggtggccagacacatctcgctccattcccactcactgtttttc agaactattttccaagcccgaactggaatcttccttcacacatctggaccaaggtgaaagactgaacctgtcctgctcca tcccaggagcacctccagccaacttcaccatccagaaggaagatacgattgtgtcacagactcaagatttcaccaagata gcctcaaagtcggacagtgggacgtatatctgcactgcaggtattgacaaagtggtcaagaaaagcaacacagtccagat agtcgtatgtggtgagtatattgttgcgactcagaggacatccggggttgaatgggagaaaggaaatttatctgcagctg ccgccctctccggtctccggtctgagcagactcaggcagggtaagaactagagggagagaagtgcgaaatcaaaggccaa agaaacaaggaggtattcctgctcagaacactgattcactgatgatgatgtggcctctgacttgcaagattctggcaaga ttctgcctcctggagcaagacccacccaaaagttcaggaaggaaacactacttagtcaatgttaaacttttctttttttt ttttgagacgtgtcgcccaggctagagtgcagtggcacgatagctcactgcaacctctgcctcctaggttcaagtgatct cctgcctcagcctcccaagtagctgggattacaggtgcccaccaccacgtctgcctaatttttgtatttttatttttatt acttttatttatttatttatttattttttttcggtctgtcacccaggctggcagtgccagtggcacaatctgggcatcac tggaaagcatccgcactcctgggtacacgagcattctcctgcctcagccctcccaagtgggtgtggactacaggacacac cgttcacttgagtccaggagttcaagaccagcctgagcacatagtgagaccctgtctctacaaaaaataaagaattagcc aggtgtggtgtgcacctatagtcccagctactcgggaggctgaggtaggaggattgcttgattctgggaggttgtagtga gctgtcatcgcaccagtgcactccagcctgggtaatagagtgagaccctgtctcaaatacacacacacacacacacacac acacattttgttggctacttgttgtactttttctatgttttctgtgtctttgctcaacacaagaaaagtatattatgtgt gcatgtgcgtgtgagatatggtaaaatatgaacatgtatttctggggatgtaatgttttccttgaatttctgtcattctc tgttttgcttattgtacttctctttccctttcccttctcaccacacacacacacacacacacacacacacacacacagcc tgtcagtctcataggtgtcctataaaggtaaatggcaggcaggcatttgaaattacagcagggatagaaagcaaaactca ggctttggaggaggaacctcttgtgctggatgctttgtttttaccttcagtgccttttggattgtttctccctctgttct agaaatgctctcccagcccaggatttcttatgatgcccagtttgaggtcataaaaggacagaccatcgaagtccgttgcg aatcgatcagtggaactttgcctatttcttaccaacttttaaaaacaagtaaagttttggagaatagtaccaagaactca aatgatcctgcggtattcaaagacaaccccactgaagacgtcgaataccagtgtgttgcagataattgccattcccacgc caaaatgttaagtgaggttctgagggtgaaggtgataggtaagttgctgtgctgtgagaagaaatcatgtgggcttgggg cattctttcacccccagggactgtggggacaataagagaagtagggggccaggtgcggtggctcatgcctgtaatcccag cactttaggaggccaaggccggtgaatcattgaggccaggagttcaagaccagcctggccaacatggtgaaaccccatct ctactaaaaatacaaaaattagctgggcatgatggcgtgcgcctataatcccagccactcgggaggctgaggcaggagaa ttgcttgaacccaggaagcacaggttgcactgagccaagttgcgccattgcactccagcctgagcaacaagagcgaaact ccatctaaaaaaaaaaaagcgagagaagtagtgggtgcttatgcaaagtccatatactagatatgcaccaaagcagggcc aaggttcagtaaaggaggctggaaaatatttgggggctattgatgaggacaatataatctctttccagaacctttcaaca aactgctaaaagatgataagcatgaaagtgtcctgactgcaggaagcactgaagttgtgcatatgggcttcccttagcac tttctccttttcagatacactgttctgagaattgtagatcaggactctgctgttgtgactcctagccggggaaccctgcc ttgtgtgaattcgagattagcctggccaacatggtgaaatcctgtctctaataaaaatacaaaaaattagctgggtgtgg tggtgggcacctttaatgccagctactcgggaggctgaggcacaagaatcatttgaacctgggaggcagaggctgcagtg agccaatatcattccgctacactccagcctgggcaacggagcaagactccatctcaaaaaaaaaaaaaattaacattaca tagactaagcacctaatggtgtgaggcatacaaaaaagaagacatattctttgtttcaatgctgtggtaagaaacacaag ctctcctaatgaaaatgatggacaaacatctgaatcatactaccaataagcatagaaaaaatgttgggggtcatgtttgg ttgtcacgtgaactatatccttacagtgatggtgatagtaatttagggtatgccagacttcatctagcttaagtgggtaa acattgtgaaaaagctgggctaggtgccagggcttgagaatgggtggccagagaaggctgaagatggctgaacatctcca gcaaacacatgagccaaaaggtcccatggggcacttcaaaagactgtgcgcagccaggtgcggtggctcacgcctataat cccagcactttgggagaccgaatggggtggatcacttgagcccagaggtttgtgactagcttggccaacatggcaaaacc ccgtctctactaaaaatacaaaaattagcccagcgtggtggtgggtgtcctgtagccccagctactcaggtggctgaggt ggtagaatcacttgaatccaggaggcagaggttgcagtgagccaagatcgtgccactgcactccagcctgggtgacagag tgagactctatctccacaaaaaaaaaaaaaaaaaaaaaaattaaaggactgtggccaaatcagatggctggaaacaaagg ctggagtttgggaatggagaatcaccggatatgagctgaaaaagtggctgagcctaagcgtgacaggtgtcaggtgccag tctcaggagtaggcaattgtcctgcatgcagtgaaaagccagaagatggaaggaaggacaggatgcaaatgagttctcgg aacgatccacctggtggctgggtcagggagcaggcatggtgacttcagacctcatggtacgttagaggctaatgtgaagc ccatgtgaagctgttggtttaaactgggtcgatatcagtggcacacatttactgaccatgtgtccagccctgtgtgaagt actgtagtaaattgctccaatggaaactcacaataaccacagaaggccagtaacagcattgtcgttattttatcatgacg caactgaggcttagggcagacagctggtgggtggtgggactgggatttgagcccactggtgtcccaggcccggagcttgg cttcttccattgtcttaccacagcctgcactcacaggagagtgactcataagttacaataccatctgctgaccatctgct ctcacactagaaggaaagtctacttggggagacaatttaggatccgaattttggtagttgaggatggagctaggaaaagc ggatacaggaggtagccaagttctgcttggacctgcagggagtgaggctggccgggctccaggtggaaatccccaggtga aaagggagacttggagttcaggaaagtaacctggactggagccataggtttaggtgtcagtggctcagagacagaagctc agcgtgtaggtgaaatcacccaggaggagaatggggatggaaaactgaggattgaattttgcaaaatgttcatacttccg gggaaaacaaagaataaccagtgaataagaaaggggtgccaggtaagaagggaagagaatcagagtcatgaggaacccca gaaccccagaaaaagctgagttccacgtaagacctgggcaacagtgaagtatggagagcccaagattgggagcgtggagg aagagcatccaccactgaatttaatcagccccggactcagggacgttggttggggaatcaagtgaccttcccagtttctt caaaacttgagagagagtgcagtgtcacaagattgtgactacaaaagagtgcagtcagatttcaggggtaacaagaaagt gtgaaataagggagtcaaagcataaaggaaaaaggagaaaaaatggccgatagctagagaaggcgtgggtcaagattgtc tgtggcctggcatggtggcttatgcctgtaatcccagcattttggaaggccgaggtgggcaaatcacctgaggtcaggaa ttcaagaccagcctggccaacagggcaaaaccccgtctctaaaacaacaacaacaacaaaaaaatccaaaaagttagctg ggcctggtgggcgcacctgtcattccagctactcgggaggctgaggcaggagatttgcttgaacccaggaggcacacgtt gcggtaagctgagattataccactgcactccagcctgggtgataagagcgggactctgtctcagaggaaaaaaaaaaaag ttgagcagtggctgtctcatgttcctcttcctctgcccttctttgctcagtgtgaatccttttcctgcttttcagccccg gtggatgaggtccagatttctatcctgtcaagtaaggtggtggagtctggagaggacattgtgctgcaatgtgctgtgaa tgaaggatctggtcccatcacctataagttttacagagaaaaagagggcaaacccttctatcaaatgacctcaaatgcca cccaggcattttggaccaagcagaaggctaacaaggaacaggagggagagtattactgcacagccttcaacagagccaac cacgcctccagtgtccccagaagcaaaatactgacagtcagaggtgagtcagggtctccatagcaagctgtgctgtgggc ccccaagggcaagaccagaaaacaccccccttgtaagagggagtttggggggagtctagcttatgtgactgaaggctagg agagtaatgtcctccaggctcttggttgcaagtgacagaaacccactcaaattaagtaaaaaagagaaatcgattattat aaggaattgggagaatgtcacatcgttccaattacaaattgttggcagactcaccattgagtcatcttgggtcaaacatc caaccacagaccacctgtagccaaggggattgggtcacgcagaacagacatgattggggaaccacttatgtgggtgtggg ggcggtttcctggagaagaagagggctgaaaacacatgccaaaaaggagtctactccacttgagccctggagttggagac cagcctgggcaacatggtgaaaccctgtctctacaaaaagtacaaaaataggctgggcgcagtggctcatacctgtaatc ccagctactcgggaggctgagacatgagaatcacttgaacccaggaggtagaggttgcagtgagcagagcttgctccact gcactccagcctgggcaacagagcaagactctgcctcaaaaatcaaaccaacaaaaaatagctgtgtgtggtggtgtgct cctgtagtcccagctactcgggaggctgaggtggaaggattgctcaagcccaggaagttgaggctgcagtgagctg cat cagcctctagcctgggtgacagagtgagaccctgttcaaaaagaaagaaaaagaaaagagtctacccagcaaagctggtt tgttccctccttgaggaccacagctgacctctatttgtagcagaaacaatcatttctgcaccagctctgagtgcagaacc cctcagaggtagatggatgctaaggcaagctgccagttacaagagctgtgagaatcagactgacttttgttgcttaaggc ctgatattatttcttcctggcagaggaagagcctatatacaaaaaaaattttttgttttgttttgttttcagtcattctt gccccatggaagaaaggacttattgcagtggttatcatcggagtgatcattgctctcttgatcattgcggccaaatgtta ttttctgaggaaagccaagggtgagcatagttctttccttccatactgactggtcgtccttgccaggaaaccagccaggg atgcgtggtgcttttctgacccctggattcagctaggcaaaaatgaaagctattattttcctca tgggcaaaccagaaa 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cttatagccacgactcaaatatattgatcttagaatctaaaagacttaggtctgggcgcggtggctcacgcctgtaatct caacactttgggaggccgaggtaggtggatcacttgaggtcagcagttcaaaaaccacctggccaacatggtgtaaccct gtttctactaaaaatacaaaaaattagctgggcatggtggtagatgtttataatcccagctactcaggcaggctgaggca ggagaatacccttgaacctgggaggtggaggttgcatgacctgatggacctcaacatgcacaccagtccgagcaacaaga gcgaaactccatctcaaaaaagaaagaaagaaagaaactatattcaggccaggcatggtagttcatgcctataaccccag ctctttgggaggctgaggtgggaggatcattgagcccaggagttggagaccagcctgtgcaacaaagcgagacatggaga atgtggaacgagggacccaggacccagagacagtgctggttgtcactacactgaataaatcaggcttgactttgttaggg gtactgaatttttaaaagggttttagaaaactagaatttcccttgtcactcaccctaattgttatttttcaactaggtca caatgacgatgtcagaaaccatgcaatgaaaccaataaatgataataaaggtaattatctaattacatgtttttattaga accaacttttacattaaaaaaaagactcataggaaaagaaaactaaaacttgaaggactgtggataatttcccacctctc ttaatgaccctgtacccagccgatgtgtcaatgaaggtagctagctgctttcaccagagatgctatctagtgtcctcagt gggaagtacctaaatcaaagtagggaagaactgggttatactcaaaaaaacaacaactctgtggtttctttaggcagagc ctctgaactσagacgtgcagtacacggaagttcaagtgtcctcagctgagtctcacaaaggtaagtgccactcgagtgag tccccaggcattcgctttggcttgggtttaaaccccagtggtggcgggggtgctgtgttcagtgagaagagtctgtgcac cctcagtcgctccaaaggaagtgattagcagacctaccggcctgctaagactggaaggagcaaggcccctggcctggcct gtctctgagctgtaaaatttcaataatttaaaagaaaaaaagaaaaggccaggcactgtggctcacacctgtaatcctag cactttgggaggccaaggcgggtggatcacctgagatcatatattttatatattaatatataaatataaatacatatata atatataatatatgttttctttgtgtataatatatattttataatattttatatatttttattttttatttttatatatt ttatatataatatttttatatttatattatttatatattttttattttatatatatatatatatttttttttttctttgt tgagacggagtctactctctgcccaggctggggtgcagttgcgagatcttgcaaacctctgcctccgggttaaagcagca ttctcctccctcagcctcccgagtagctgggattacaggcatgtcaccgccacagccgggtaatttatttattttttttt tgtatttttaagtagagatgggatttcaccatgttggccagcgtgaactcgaacttctgacttcaaaagatccacccccc tcagcctcccaaagtgctgggattacaggtgtgaggaattcaatttgagttttccagacccgtcctcctccttggcagct aaggagcagtgtgggaagtcaggcctgagcctcaggtgttccctctctgccttcctgtgggtggagagccaggtattacc 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ttgttttgtttttttgtttgaaacagagtctcactctgtcacccagactggagtacagcagtgccatctcagctgactgc aactccgtgcaacaccccccagcccctaaggcttaagcgatcctcccaagtagctagaaccacagacacacaccaccatg cccagctaagtttttgtatttttggtagagatgaggttttaccatgttgcccagactggtgttgaattcctgagctcaag caatccacccccttcggcctcccaaagtgctgggattacaagcgtgagccactgtgccaggcaaaaagcactgttttaga agaaccatccaattctctgaggaccctgctttttatctgaaatagcgatcacttcttaattcacttttaaaagttggtat atctacaagaagaatagaaactcaacccttgtggaacttgaccctgaataatttttgaaaaaccaattctctggggaatt tttagctcaaatacctcatttaaaaaaaaaaaaaaaaagaagaagtagtttctgcttttagtcagataaacaagctctgg ggagacttccttctacatctgaaccagctcaaaacaatccttatgccaaaggggcatattttgtggtggcatattctgat ttccttcatctgctttagggcagctggctgttcaagtgggttctctcggggtctccaggttggttctagactttctttct ttcctttcttttttttttttttgagacagggtcttcgctctgtcacccaggctggagtgcagtggcgcgatcgcagctca ctgcaacctccagctcccgggttcaagtgattcttctgcctcagcctcctgagtagctgggaccacagctactgccacca cccccgggtaattttttttgtatttttagtagagacggtgtttcaccatattggtcaggctgatctcgaactccagacct 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caagggtgagggatgaccagtttcaagcagtgtgggatgggaaagaagagtgtgacagtgacaagtgacgggagaaagat aagtcagggcttaaatccaaaggatttacatcccttgttaagaagcttcattctgtaggaaatggagttaggaatctgca tttggcagatgggagggtttatgaaagacacagaggcccacgttcaacttttgcaaagacgtgtcttccaatcccaacct ttttgtgagctacccagcaatgcaggagttaactgggcagctaatatctgaagaaatgaggcatttgccgcataaacttc ttttaggtctgggaagaactttcagcaaagatttcaggtagctcttccagtggcccctggcttcctttgttttgcccatg tcaggactcttgtaaaacagagctcgagctccagctttccagctgtcttttgggtgagcctgtcttcctcaagctcaagc ttccttatctataaagtggagatggtgatgacaatgatgataagagcaacctattaggattttaaggatgaaatgagcaa ctgcaaccaccatataaaagctgcaagctgcaaaccaccatataaaagctggttgatctcaagctcttttcatcacttgg gcaatagtaggtgtggatgggggacttaacttgatttggccatgaaatgaccctgccacatatggagaatgtagcagttg cttacccaaggcataggattcaaccaaggccaggctttgacttaggaatcagagacccacattaacatttgacttcccgc ttcttagccatgtcaccatgggcaaatttcttggcctctcaagacctctgcttcctaatctgtaaactgggaatcataaa ctccctcacttggttgttgcaagggttgaatgagcacctatcaatctccagagctttttctttttaagtgtgagcgagtt tattagagaagtaaagagacccaagagtgcctactccatagacagagcagccactgtgacactgtacccattaaacacta actctccattgcccctccagcaacccctagcacccactgtctactttctgtctctatgtggttgtctatttgagggacat cacataagtggagtcatatatttgtcctttcatgtctcccttatttcatttagcataacgttttcaagggtttcctgtgt tgtgaatatatcagaatttcattctctttttaaggtagaatcatatcattttaaaacatttcagttggaccatctaagtt cagtccttcattttcaacaattaaaaaacagccctcaaccgggtgcatctcacgttagctagagacagaactggagctag aagtcagatctcttaccaaagttgcctttcttcttctgtgggtaagtggggcacccttgggacgctgtgctgggcgtaca tgggtgcttgatgaagttacttggtggactgatgtgattgatgtccaacatgtatgcagggacagaggctatggtcccta cagagcaggcatggagagaaggagaaatacatacgggcaggagccaggagagggagggtgtagtgagcagagaccgcgcc actgcactccagcctgagtgacagagtgagaatccatctaaaaaattgcttactaaagaagtggtctcctgaggtcttaa gacgttcctggcaatgtcttgagtgggtgggagagagcctccagtcattgagctgtggaatttcagaggtgagaaccaca cctaacccccaattactttcccctgtttgcctcagtgacacagctgcaggaaccctggtgggtgttgtattaagtaaatt tgacctttattctttgcagatctgtgaaatgttgtcttctgaggggccacgtgtatctgtagtgctgaggactccttggg gcctctgaagtcacagagagaacctgcagggtgggggaccagtgtgtgacagccctgctttgcattttctttgagaagtg ctgtcattttgcatttctctccaccaggggaatcttcaatcttgagaggtgtgatcataacttgccttgtttcttgt^'cgc tacagagaacggaaggctcccttgatggaacttagacagcaaggccagatgcacatccctggaaggacatccatgttccg agaagaacagatgatccctgtatttcaagacctctgtgcacttatttatgaacctgccctgctcccacagaacacagcaa ttcctcaggctaagctgccggttcttaaatccatcctgctaagttaatgttgggtagaaagagatacagaggggctgttg aatttcccacataccctccttccaccaagttggaacatccttggaaattgggaagagcacaagaggagatccagggcaag gccattgggatattctgaaacttgaatattttgttttgtgcagagataaagaccttttccatgcaccctcatacacagaa accaattttcttttttatactcaatcatttctagcgcatggcctggttagaggctggttttttctcttttcctttggtcc ttcaaaggcttgtagttttgggtagtccttgttctttggaaatacacagtgctgaccagacagcctccccctgtcccctc tatgacctcgccctccacaaatgggaaaaccagactacttgggagcaccgcctgtgaaataccaacctgaagacacggtt cattcaggcaacgcacaaaacagaaaatgaaggtggaacaagcacatatgttcttcaactgtttttgtctacactctttc tcttttcctctacatgctgaaggctgaaagacaggaaagatggtgccatcagcaaatattattcttaattgaaaacttga aatgtgtatgtttcttactaatttttaaaaatgtattccttgccagggcaggcaaggtcgtcacgcctgtaatcccagca cttcaggaggctgaggtgggcggatcgaattccgggagaagtgaccagagcaatttctgcttttcacagggcgggtttct caacggtgacttgtgggcagtgccttctgctgagcgagtcatggcccgaaggcagaactaactgtgcctgcagtcttcac tctcaggatgcagccgaggtgggcccaaggggccacgatgtggcttggagtcctgctgacccttctgctctgttcaagcc ttgagggtcaagaaaactctttcacaatcaacagtgttgacatgaagagcctgccggactggacggtgcaaaatgggaag aacctgaccctgcagtgcttcgcggatgtcagcaccacctctcacgtcaagcctcagcaccagatgctgttctataagga tgacgtgctgttttacaacatctcctccatgaagagcacagagagttattttattcctgaagtccggatctatgactcag ggacatataaatgtactgtgattgtgaacaacaaagagaaaaccactgcagagtaccagctgttggtggaaggagtgccc agtcccagggtgacactggacaagaaagaggccatccaaggtgggatcgtgagggtcaactgttctgtcccagaggaaaa ggccccaatacacttcacaattgaaaaacttgaactaaatgaaaaaatggtcaagctgaaaagagagaagaattctcgag accagaattttgtgatactggaattccccgttgaggaacaggaccgcgttttatccttccgatgtcaagctaggatcatt tctgggatccatatgcagacctcagaatctaccaagagtgaactggtcaccgtgacggaatccttctctacacccaagtt ccacatcagccccaccggaatgatcatggaaggagctcagctccacattaagtgcaccattcaagtgactcacctggccc aggagtttccagaaatcataattcagaaggacaaggcgattgtggcccacaacagacatggcaacaaggctgtgtactca gtcatggccatggtggagcacagtggcaactacacgtgcaaagtggagtccagccgcatatccaaggtcagcagcatcgt ggtcaacataacagaactattttccaagcccgaactggaatcttccttcacacatctggaccaaggtgaaagactgaacc tgtcctgctccatcccaggagcacctccagccaacttcaccatccagaaggaagatacgattgtgtcacagactcaagat ttcaccaagatagcctcaaagtcggacagtgggacgtatatctgcactgcaggtattgacaaagtggtcaagaaaagcaa cacagtccagatagtcgtatgtgaaatgctctcccagcccaggatttcttatgatgcccagtttgaggtcataaaaggac agaccatcgaagtccgttgcgaatcgatcagtggaactttgcctatttcttaccaacttttaaaaacaagtaaagttttg gagaatagtaccaagaactcaaatgatcctgcggtattcaaagacaaccccactgaagacgtcgaataccagtgtgttgc agataattgccattcccatgccaaaatgttaagtgaggttctgagggtgaaggtgatagccccggtggatgaggtccaga tttctatcctgtcaagtaaggtggtggagtctggagaggacattgtgctgcaatgtgctgtgaatgaaggatctggtccc atcacctataagttttacagagaaaaagagggcaaacccttctatcaaatgacctcaaatgccacccaggcattttggac caagcagaaggctagcaaggaacaggagggagagtattactgcacagccttcaacagagccaaccacgcctccagtgtcc ccagaagcaaaatactgacagtcagagtcattcttgccccatggaagaaaggacttattgcagtggttatcatcggagtg atcattgctctcttgatcattgcggccaaatgttattttctgaggaaagccaaggccaagcagatgccagtggaaatgtc caggccagcagtaccacttctgaactccaacaacgagaaaatgtcagatcccaatatggaagctaacagtcattacggtc acaatgacgatgtcagaaaccatgcaatgaaaccaataaatgataataaagagcctctgaactcagacgtgcagtacacg gaagttcaagtgtcctcagctgagtctcacaaagatctaggaaagaaggacacagagacagtgtacagtgaagtccggaa agctgtccctgatgccgtggaaagcagatactctagaacggaaggctcccttgatggaacttagacagcaaggccagatg cacatccctggaaggacatccatgttccgagaagaacagataatccctgtatttcaagacctctgtgcacttatttatga acctgccctgctcccacagaacacagcaattcctcaggctaagctgccggttcttaaatccatcctgctaagttaatgtt gggtagaaagagatacagagggg (SEQ ID NO: 12157) tggtcatctcagtttcttttctcaccttgactgcaagatgaaactccttgtgctagctgtgctgctcacagtggccgccg ccgacagcggcatcagccctcgggccgtgtggcagttccgcaaaatgatcaagtgcgtgatcccggggagtgaccccttc ttggaatacaacaactacggctgctactgtggcttggggggctcaggcacccccgtggatgaactggacaagtgctgcca gacacatgacaactgctatgaccaggccaagaagctggacagctgtaaatttctgctggacaacccgtacacccaσacct attcatactcgtgctctggctcggcaatcacctgtagcagcaaaaacaaagagtgtgaggccttcatttgcaactgcgac cgcaacgctgccatctgcttttcaaaagctccatataacaaggcacacaagaacctggacaccaagaagtattgtcagag ttgaatatcacctctcaaaagcatcacctctatctgcctcatctcacactgtactctccaataaagcaccttgttgaaag aa (SEQ ID NO: 12158) ctgcagaggctcaatcactgttcattgcagccttgacctccctggctcacgagatcctcccatctcagcctcctgagttg ctgggatcacaggtgcaatccaccaccacacctggttaacatttttttttttagagatgaggtctctctatgttgcccag gctgcacttccttcttgtctcccttatcccagcgtccgactgaactgacggctttgctttccccaaccagcccgtgaagc tgggctgagtacaaagtggtgggtatgagggtcaagattgtaagatctgaaaactccagaaaccatccctttggttaaca gttgctaaggacaaatgcataacatattttccagtgatcccatgctggcaaatcgtgagggtcattcctgcaacagacag attcaaggccagccccaaactcagccaagagcaaagcaaacactccagccttatctgggcagggttgtgtggagactgac tataagactatacctgagactggtcatctcagttcttttctcaccttgactgcaagatgaaactccttgtgctagctgtg ctgctcacaggtaggcaagtctccccggctccacccgcctttctctcccaagtgagctaagatctcactcctctggaatg ggggccacacacagcaaacagggatggccagccccgcagtctcaattcgaggttcccagtgggcttaagggctcctctat tggggttccctcaaggctggcactttttcaacctgcaagtctgaactcagattgcctgagctaagaaagcttgcctttat tttcttttttccagacagggtcttgctctataacccaggctggagttcagtggcatgatcatagctcaccacagcttcca actcgtgggctcaagtgatcctcccaccttactcaactaagtagttaggccaatctcccatttattttattttattttaa tttttatttttattttactttattttatttttgagacggggctcactctgtcgccaggctggagtgcggtgggctgatct cagatcactacaacctccatctcctggttcaaataattctcttgcctcagcctctcaagtagctggacttgtagctctca agtagctggcacacaccaccatgcccagctaattttttgtgtgttttttttggtagagacaggttttcaccatgttggcc aggctgggtgacctcccttttagattctcctcatcctgctctattcttcccctttctaaatgcagtatccagtttcctta cttatacactttattattattcttattattattgagacagagtcttgctttgtgcccaaggctggagtacagtggtgcga tctcggctcactgcaagctccacctgctgggttcacgccattctcccgcctcagcctccccagtagctgggactaaagcg cctgccaccacgccccgctaatttttttgtatttttaataaagacggggtttcatcgtgttagccaggatggtctcgatc tcatgaccttgtgatccgcctgcctcggcctcccaaatgctggattacaggcatgagccaccgtgcccggccttatcaca tttattatttattgtttttctctcccactaggttgtaagctccatgaggttagagattattattattat attattatta ttattattattattattattattatatctgttcactgctgtatctctagctcctaggacagagcctggcacatagtaagt gctcaataaatattcactggataaacagtgcagatagtttaaaactatctgacctagggaggctgaggcaggagaatggc gtgaacccgggaagcagagtttgcagtgagctgaaatcgtgtcactgcactccaacctgggcaacagagcaagactccat ctcaaaaaaaaaaaaaaaactatcaggcctagctgggtggcacatgcctgtaatcctagctgaggcggtagggtcccaga agaagaagaagaagaaaaagaagaagatatatatatatatacacacacacaaagatataaactttatatatataaagttt tcattaaaaaaaaaaaaaacctctacccactttcactttaccaggttcctgggtccaacggtcttcagaggaggcagctg gcaggggtcagggaggcagcgtgggacccgagggagcaggaaggcagtgtgtccccggggtgctggcagaccgatttgaa ctctggctatgtcttcttgcagtggccgccgccgacagcggcatcagccctcgggccgtgtggcagttccgcaaaatgat caagtgcgtgatcccggggagtgaccccttcttggaatacaacaactacggctgctactgtggcttggggggctcaggca cccccgtggatgaactggacaagtaagtgatccgcctgcaggaaaattggagtgcctgccgggggcggggtggggcacca cgccaaggatctcacgaggcatacaaaggggacttgcatatctgctaaggataacatattttcacctcttgtcaaataaa catatatgttccaagaggaccctgtagcgaacgcaccccgttagagatggaaacattgaccgacgtgcaaaacagtgggc gatgctgccctccagtggcagaatgtagcaacattaaacatcacagcacctatccacgtgtcattttctagcagtggttg tcactgccccttctggaatacaggattttactgtattcttgcaaccatgttaaaaatcgctttcaggccaggcgcggtgg ctcatgcctgtaatcccagcactttgggaggccgaggcgggcggatcacttgaggtcaggagttcgagaccagcctggcc aacatggtgaaaccctgtctctactaaaaaatacaaaaattagccggacatggtggcgagcgcctgtaaccccagctact tgggagactgagttggaggtttcatgagccaaggtcgtgtcactgctgtccagcctgggtaacagagcaactctgtctca aaaaaaaaaaatgctttcaataaatatatgataaaaggacttatattttttcaagccataggatcatttctcctgaagca tcttggcgaagt atccccacctgttcctgagagtgggcaggtgagggctgacctattgctctgcacttactcctatctc agctgtccctcccactttccaggtgctgccagacacatgacaactgctacgaccaggccaagaagctggacagctgtaaa tttctgctggacaacccgtacacccacacctattcatactcgtgctctggctcggcaatcacctgtagcagtaggtttat cccttccttgaccta (SEQ ID NO: 12159) gcccactcccaccgccagctggaaccctggggactacgacgtccctcaaaccttgcttctaggagataaaaagaacatcc agtcatggataaaaatgagctggttcagaaggccaaactggccgagcaggctgagcgatatgatgacatggcagcctgca tgaagtctgtaactgagcaaggagctgaattatccaatgaggagaggaatcttctctcagttgcttataaaaatgttgta ggagcccgtaggtcatcttggagggtcgtctcaagtattgaacaaaagacggaaggtgctgagaaaaaacagcagatggc tcgagaatacagagagaaaattgagacggagctaagagatatctgcaatgatgtactgtctcttttggaaaagttcttga tccccaatgcttcacaagcagagagcaaagtcttctatttgaaaatgaaaggagattactaccgttacttggctgaggtt gccgctggtgatgacaagaaagggattgtcgatcagtcacaacaagcataccaagaagcttttgaaatcagcaaaaagga aatgcaaccaacacatcctatcagactgggtctggcccttaacttctctgtgttctattatgagattctgaactccccag agaaagcctgctctcttgcaaagacagcttttgatgaagccattgctgaacttgatacattaagtgaagagtcatacaaa gacagcacgctaataatgcaattactgagagacaacttgacattgtggacatcggatacccaaggagacgaagctgaagc aggagaaggaggggaaaattaaccggccttccaacttttgtctgcctcattctaaaatttacacagtagaccatttgtca tccatgctgtcccacaaatagttttttgtttacgatttatgacaggtttatgttacttctatttgaatttctatatttcc catgtggtttttatgtttaatattaggggagtagagccagttaacatttagggagttatctgttttcatcttgaggtggc caatatggggatgtggaatttttatacaagttataagtgtttggcatagtacttttggtacattgtggcttcaaaagggc cagtgtaaaactgcttccatgtctaagcaaagaaaactgcctacatactggtttgtcctggcggggaataaaagggatca ttggttccagtcacaggtgtagtaattgtgggtactttaaggtttggagcacttacaaggctgtggtagaatcatacccc atggataccacatattaaaccatgtatatctgtggaatactcaatgtgtacacctttgactacagctgcagaagtgttcc tttagacaaagttgtgacccattttactctggataagggcagaaacggttcacattccattatttgtaaagttacctgct gttagctttcattatttttgctacactcattttatttgtatttaaatgttttaggcaacctaagaacaaatgtaaaagta aagatgcaggaaaaatgaattgcttggtattcattacttcatgtatatcaagcacagcagtaaaacaaaaacccatgtat ttaacttttttttaggatttttgcttttgtgattttttttttttttttttgatacttgcctaacatgcatgtgctgtaaa aatagttaacagggaaataacttgagatgatggctagctttgtttaatgtcttatgaaattttcatgaacaatccaagca taattgttaagaacacgtgtattaaattcatgtaagtggaataaaagttttatgaatggacttttcaactactttctcta cagcttttcatgtaaattagtcttggttctgaaacttctctaaaggaaattgtacattctttgaaatttattccttattc cctcttggcagctaatgggctcttaccaagtttaaacacaaaatttatcataacaaaaatactactaatataactactgt ttccatgtcccatgatcccctctcttcctccccaccctgaaaaaaatgagttcctattttttctgggagagggggggatt gattagaaaaaaatgtagtgtgttccatttaaaattttggcatatggcattttctaacttaggaagccacaatgttcttg gcccatcatgacattgggtagcattaactgtaagttttgtgcttccaaatcactttttggtttttaagaatttcttgata ctcttatagcctgccttcaattttgatcctttattctttctatttgtcaggtgcacaagattaccttcctgttttagcct tctgtcttgtcaccaaccattcttacttggtggccatgtacttggaaaaaggccgcatgatctttctggctccactcagt gtctaaggcaccctgcttcctttgcttgcatcccacagactatttccctcatcctatttactgcagcaaatctctcctta gttgatgagactgtgtttatctccctttaaaaccctacctatcctgaatggtctgtcattgtctgcctttaaaatccttc ctctttcttcctcctctattctctaaataatgatggggctaagttatacccaaagctcactttacaaaatatttcctcag tactttgcagaaaacaccaaacaaaaatgccattttaaaaaaggtgtattttttcttttagaatgtaagctcctcaagag cagggacaatgttttctgtatgttctattgtgcctagtacactgtaaatgctcaataaatattgatgatgggaggcagtg agtcttgatgataagggtgagaaactgaaatccc (SEQ ID NO: 12160) tggtcatctcagtttcttttctcaccttgactgcaagatgaaactccttgtgctagctgtgctgctcacagtggccgccg ccgacagcggcatcagccctcgggccgtgtggcagttccgcaaaatgatcaagtgcgtgatcccggggagtgaccccttc ttggaatacaacaactacggctgctactgtggcttggggggctcaggcacccccgtggatgaactggacaagtgctgcca gacacatgacaactgctatgaccaggccaagaagctggacagctgtaaatttctgctggacaacccgtacacccacacct attcatactcgtgctctggctcggcaatcacctgtagcagcaaaaacaaagagtgtgaggccttcatttgcaactgcgac cgcaacgctgccatctgcttttcaaaagctccatataacaaggcacacaagaacctggacaccaagaagtattgtcagag ttgaatatcacctctcaaaagcatcacctctatctgcctcatctcacactgtactctccaataaagcaccttgttgaaag aactgcagaggctcaatcactgttcattgcagccttgacctccctggctcacgagatcctcccatctcagcctcctgagt tgctgggatcacaggtgcaatccaccaccacacctggttaacatttttttttttagagatgaggtctctctatgttgccc aggctgcacttccttcttgtctcccttatcccagcgtccgactgaactgacggctttgctttccccaaccagcccgtgaa gctgggctgagtacaaagtggtgggtatgagggtcaagattgtaagatctgaaaactccagaaaccatccctttggttaa cagttgctaaggacaaatgcataacatattttccagtgatcccatgctggcaaatcgtgagggtcattcctgcaacagac agattcaaggccagccccaaactcagccaagagcaaagcaaacactccagccttatctgggcagggttgtgtggagactg actataagactatacctgagactggtcatctcagttcttttctcaccttgactgcaagatgaaactccttgtgctagctg tgctgctcacaggtaggcaagtctccccggctccacccgcctttctctcccaagtgagctaagatctcactcctctggaa tgggggccacacacagcaaacagggatggccagccccgcagtctcaattcgaggttcccagtgggcttaagggctcctct attggggttccctcaaggctggcactttttcaacctgcaagtctgaactcagattgcctgagctaagaaagcttgccttt attttcttttttccagacagggtcttgctctataacccaggctggagttcagtggcatgatcatagctcaccacagcttc caactcgtgggctcaagtgatcctcccaccttactcaactaagtagttaggccaatctcccatttattttattttatttt aatttttatttttattttactttattttatttttgagacggggctcactctgtcgccaggctggagtgcggtgggctgat ctcagatcactacaacctccatctcctggttcaaataattctcttgcctcagcctctcaagtagctggacttgtagctct caagtagctggcacacaccaccatgcccagctaattttttgtgtgttttttttggtagagacaggttttcaccatgttgg ccaggctgggtgacctcccttttagattctcctcatcctgctctattcttcccctttctaaatgcagtatccagtttcct tacttatacactttattattattcttattattattgagacagagtcttgctttgtgcccaaggctggagtacagtggtgc gatctcggctcactgcaagctccacctgctgggttcacgccattctcccgcctcagcctccccagtagctgggactaaag cgcctgccaccacgccccgctaatttttttgtatttttaataaagacggggtttcatcgtgttagccaggatggtctcga tctcatgaccttgtgatccgcctgcctcggcctcccaaatgctggattacaggcatgagccaccgtgcccggccttatca catttattatttattgtttttctctcccactaggttgtaagctccatgaggttagagattattattattattattattat tattattattattattattattattatatctgttcactgctgtatctctagctcctaggacagagcctggcacatagtaa gtgctcaataaatattcactggataaacagtgcagatagtttaaaactatctgacctagggaggctgaggcaggagaatg gcgtgaacccgggaagcagagtttgcagtgagctgaaatcgtgtcactgcactccaacctgggcaacagagcaagactcc atctcaaaaaaaaaaaaaaaactatcaggcctagctgggtggcacatgcctgtaatcctagctgaggcggtagggtccca gaagaagaagaagaagaaaaagaagaagatatatatatatatacacacacacaaagatataaactttatatatataaagt tttcattaaaaaaaaaaaaaacctctacccactttcactttaccaggttcctgggtccaacggtcttcagaggaggcagc tggcaggggtcagggaggcagcgtgggacccgagggagcaggaaggcagtgtgtccccggggtgctggcagaccgatttg aactctggctatgtcttcttgcagtggccgccgccgacagcggcatcagccctcgggccgtgtggcagttccgcaaaatg atcaagtgcgtgatcccggggagtgaccccttcttggaatacaacaactacggctgctactgtggcttggggggctcagg cacccccgtggatgaactggacaagtaagtgatccgcctgcaggaaaattggagtgcctgccgggggcggggtggggcac cacgccaaggatctcacgaggcatacaaaggggacttgcatatctgctaaggataacatattttcacctcttgtcaaata aacatatatgttccaagaggaccctgtagcgaacgcaccccgttagagatggaaacattgaccgacgtgcaaaacagtgg gcgatgctgccctccagtggcagaatgtagcaacattaaacatcacagcacctatccacgtgtcattttctagcagtggt tgtcactgccccttctggaatacaggattttactgtattcttgcaaccatgttaaaaatcgctttcaggccaggcgcggt ggctcatgcctgtaatcccagcactttgggaggccgaggcgggcggatcacttgaggtcaggagttcgagaccagcctgg ccaacatggtgaaaccctgtctctactaaaaaatacaaaaattagccggacatggtggcgagcgcctgtaaccccagcta cttgggagactgagttggaggtttcatgagccaaggtcgtgtcactgctgtccagcctgggtaacagagcaactctgtct caaaaaaaaaaaatgctttcaataaatatatgataaaaggacttatattttttcaagccataggatcatttctcctgaag catcttggcgaagtcatccccacctgttcctgagagtgggcaggtgagggctgacctattgctctgcacttactcctatc tcagctgtccctcccactttccaggtgctgccagacacatgacaactgctacgaccaggccaagaagctggacagctgta aatttctgctggacaacccgtacacccacacctattcatactcgtgctctggctcggcaatcacctgtagcagtaggttt atcccttccttgacctagcccactcccaccgccagctggaaccctggggactacgacgtccctcaaaccttgcttctagg agataaaaagaacatccagtcatggataaaaatgagctggttcagaaggccaaactggccgagcaggctgagcgatatga tgacatggcagcctgcatgaagtctgtaactgagcaaggagctgaattatccaatgaggagaggaatcttctctcagttg cttataaaaatgttgtaggagcccgtagg catcttggagggtcgtctcaagtattgaacaaaagacggaaggtgctgag aaaaaacagcagatggctcgagaatacagagagaaaattgagacggagctaagagatatctgcaatgatgtactgtctct tttggaaaagttcttgatccccaatgcttcacaagcagagagcaaagtcttctatttgaaaatgaaaggagattactacc gttacttggctgaggttgccgctggtgatgacaagaaagggattgtcgatcagtcacaacaagcataccaagaagctttt gaaatcagcaaaaaggaaatgcaaccaacacatcctatcagactgggtctggcccttaacttctctgtgttctattatga gattctgaactccccagagaaagcctgctctcttgcaaagacagcttttgatgaagccattgctgaacttgatacattaa gtgaagagtcatacaaagacagcacgctaataatgcaattactgagagacaacttgacattgtggacatcggatacccaa ggagacgaagctgaagcaggagaaggaggggaaaattaaccggccttccaacttttgtctgcctcattctaaaatttaca cagtagaccatttgtcatccatgctgtcccacaaatagttttttgtttacgatttatgacaggtttatgttacttctatt tgaatttctatatttcccatgtggtttttatgtttaatattaggggagtagagccagttaacatttagggagttatctgt tttcatcttgaggtggccaatatggggatgtggaatttttatacaagttataagtgtttggcatagtacttttggtacat tgtggcttcaaaagggccagtgtaaaactgcttccatgtctaagcaaagaaaactgcctacatactggtttgtcctggcg gggaataaaagggatcattggttccagtcacaggtgtagtaattgtgggtactttaaggtttggagcacttacaaggctg tggtagaatcataccccatggataccacatattaaaccatgtatatctgtggaatactcaatgtgtacacctttgactac agctgcagaagtgttcctttagacaaagttgtgacccattttactctggataagggcagaaacggttcacattccattat ttgtaaagttacctgctgttagctttcattatttttgctacactcattttatttgtatttaaatgttttaggcaacctaa gaacaaatgtaaaagtaaagatgcaggaaaaatgaattgcttggtattcattacttcatgtatatcaagcacagcagtaa aacaaaaacccatgtatttaacttttttttaggatttttgcttttgtgattttttttttttttttttgatacttgcctaa catgcatgtgctgtaaaaatagttaacagggaaataacttgagatgatggctagctttgtttaatgtcttatgaaatttt catgaacaatccaagcataattgttaagaacacgtgtattaaattcatgtaagtggaataaaagttttatgaatggactt ttcaactactttctctacagcttttcatgtaaattagtcttggttctgaaacttctctaaaggaaattgtacattctttg aaatttattccttattccctcttggcagctaatgggctcttaccaagtttaaacacaaaatttatcataacaaaaatact actaatataactactgtttccatgtcccatgatcccctctcttcctccccaccctgaaaaaaatgagttcctattttttc tgggagagggggggattgattagaaaaaaatgtagtgtgttccatttaaaattttggcatatggcattttctaacttagg aagccacaatgttcttggcccatcatgacattgggtagcattaactgtaagttttgtgcttccaaatcactttttggttt ttaagaatttcttgatactcttatagcctgccttcaattttgatcc ttat ctttc a tgtcaggtgcacaagatta ccttcctgttttagccttctgtcttgtcaccaaccattcttacttggtggccatgtacttggaaaaaggccgcatgatct ttctggctccactcagtgtctaaggcaccctgcttcctttgcttgcatcccacagactatttccctcatcctatttactg cagcaaatctctccttagttgatgagactgtgtttatctccctttaaaaccctacctatcctgaatggtctgtcattgtc tgcctttaaaatccttcctctttcttcctcctctattctctaaataatgatggggctaagttatacccaaagctcacttt acaaaatatttcctcagtactttgcagaaaacaccaaacaaaaatgccattttaaaaaaggtgtattttttcttttagaa tgtaagctcctcaagagcagggacaatgttttctgtatgttctattgtgcctagtacactgtaaatgctcaataaatatt gatgatgggaggcagtgagtcttgatgataagggtgagaaactgaaatccc (SEQ ID NO.-12161) gctgtgcaacctcggcgccatgcgcaacctctatgcgatgcaccggcggctgcagcggcacccgcgctcctgcaccaggg actgtgccgagccgcgcgcggacgggagggaagcgtcccctcagcccctggaggagctggatcacctcctgctgctggcg ctgatgaccgtgctcttcactatgtgttctctgcccgtaatttatcgcgcttactatggagcatttaaggatgtcaagga gaaaaacaggacctctgaagaagcagaagacctccgagccttgcgatttctatctgtgatttcaattgtggacccttgga tttttatcattttcagatctccagtatttcggatattttttcacaagattttcattagacctcttaggtacaggagccgg tgcagcaattccactaacatggaatccagtctgtgacagtgtttttcactctgtggtaagctgaggaatatgtcacattt tcagtcaaagaacca (SEQ ID NO: 12162) gaattctggctattttcctcctgccgttccgactcggcaccagagtctgtctctactgagaacgcagcgcgtcagggccg agctcttcactggcctgctccgcgctcttcaatgccagcgccaggcgctcaccctgcagagcgtcccgcctctcaaagag gggtgtgacccgcgagtttagataggaggttcctgccgtggggaacaccccgccgccctcggagctttttctgtggcgca gcttctccgcccgagccgcgcgcggagctgccgggggctccttagcacccgggcgccggggccctcgcccttccgcagcc ttcactccagccctctgctcccgcacgccatgaagtcgccgttctaccgctgccagaacaccacctctgtggaaaaaggc aactcggcggtgatgggcggggtgctcttcagcaccggcctcctgggcaacctgctggccctggggctgctggcgcgctc ggggctggggtggtgctcgcggcgtccactgcgcccgctgccctcggtcttctacatgctggtgtgtggcctgacggtca ccgacttgctgggcaagtgcctcctaagcccggtggtgctggctgcctacgctcagaaccggagtctgcgggtgcttgcg cccgcattggacaactcgttgtgccaagccttcgccttcttcatgtccttctttgggctctcctcgacactgcaactcct ggccatggcactggagtgctggctctccctagggcaccctttcttctaccgacggcacatcaccctgcgcctgggcgcac tggtggccccggtggtgagcgccttctccctggctttctgcgcgctacctttcatgggcttcgggaagttcgtgcagtac tgccccggcacctggtgctttatccagatggtccacgaggagggctcgctgtcggtgctggggtactctgtgctctactc cagcctcatggcgctgctggtcctcgccaccgtgctgtgcaacctcggcgccatgcgcaacctctatgcgatgcaccggc ggctgcagcggcacccgcgctcctgcaccagggactgtgccgagccgcgcgcggacgggagggaagcgtcccctcagccc ctggaggagctggatcacctcctgctgctggcgctgatgaccgtgctcttcactatgtgttctctgcccgtaattgtgag tccccgggccccgagg (SEQ ID NO .-12163) gggccgccgtcggcgcgctgggtgcgggaagggggctctggatttcggtccctcccctttttcctctgagtctcggaacg ctccagctctcagaccctcttcctcccaggtaaaggccgggagaggagggcgcatctcttttccaggcaccccaccatgg gcaatgcctccaatgactcccagtctgaggactgcgagacgcgacagtggcttcccccaggcgaaagcccagccatcagc tccgtcatgttctcggccggggtgctggggaacctcatagcactggcgctgctggcgcgccgctggcggggggacgtggg gtgcagcgccggccgcaggagctccctctccttgttccacgtgctggtgaccgagctggtgttcaccgacctgctcggga cctgcctcatcagcccagtggtactggcttcgtacgcgcggaaccagaccctggtggcactggcgcccgagagccgcgcg tgcacctacttcgctttcgccatgaccttcttcagcctggccacgatgctcatgctcttcgccatggccctggagcgcta cctctcgatcgggcacccctacttctaccagcgccgcgtctcggcctccgggggcctggccgtgctgcctgtcatctatg cagtctccctgctcttctgctcgctgccgctgctggactatgggcagtacgtccagtactgccccgggacctggtgcttc atccggcacgggcggaccgcttacctgcagctgtacgccaccctgctgctgcttctcattgtctcggtgctcgcctgcaa cttcagtgtcattctcaacctcatccgcatgcaccgccgaagccggagaagccgctgcggaccttccctgggcagtggcc ggggcggccccggggcccgcaggagaggggaaagggtgtccatggcggaggagacggaccacctcattctcctggctatc atgaccatcaccttcgccgtctgctccttgcctttcacgatttttgcatatatgaatgaaacctcttcccgaaaggaaaa atgggacctccaagctcttaggtttttatcaattaattcaataattgacccttgggtctttgccatccttaggcctcctg ttctgagactaatgcgttcagtcctctgttgtcggatttcattaagaacacaagatgcaacacaaacttcctgttctaca cagtcagatgccagtaaacaggctgacctttgaggtcagtagtttaaaagttcttagttatatagcatctggaagatcat tttgaaattgttccctggagaaatgaaaacagtgtgtaaacaaaatgaagctgccctaataaaaaggagtatacaaacat ttaagctgtggtcaaggctacagatgtgctgacaaggcacttcatgtaaagtgtcagaaggagctacaaaacctaccctc aatgagcatggtacttggcctttggaggaacaatcggctgcattgaagatccagctgcctattgatttaagctttcctgt tgaatgacaaagtatgtggttttgtaatttgtttgaaaccccaaacagtgactgtactttctattttaatcttgctacta ccgttatacacatatagtgtacagccagaccagattaaacttcatatgtaatctctaggaagtcaatatgtggaagcaac caagcctgctgtcttgtgatcacttagcgaaccctttatttgaacaatgaagttgaaaatcataggcaccttttactgtg atgtttgtgtatgtgggagtactctcatcactacagtattactcttacaagagtggactcagtgggttaacatcagtttt gtttactcatcctccaggaactgcaggtcaagttgtcaggttatttattttataatgtccatatgctaatagtgatcaag aagactttaggaatggttctctcaacaagaaataatagaaatgtctcaaggcagttaattctcattaatactcttattat cctatttctgggggaggatgtacgtggccatgtatgaagccaaatattaggcttaaaaactgaaaaatctggttcattct tcagatatactggaacccttttaaagttgatattggggccatgagtaaaatagattttataagatgactgtgttgtacca aaattcatctgtctatattttatttaggggaacatggtttgactcatcttatatgggaaaccatgtagcagtgagtcata tcttaatatat tctaaatgtttggcatgtaaatgtaaactcagcatcaaaatatttcagtgaatttgcactgtttaatc atagttactgtgtaaactcatctgaaatgttacaaaaataaactataaaaca (SEQ ID NO: 12164) agagaggaaggcgtggctccctcccgggccagtgagccctggcgccgccgcggccgcggtcccagcagcggagtagggcg gcggctgcgccccgcaccatggggggcagcccagccccagccgcggtaaacgccgacctccgccgccgcccgcgccgcgt ctgccccctcccgctgcggctctctggacgccatcccctcctcacctcgaagccaacatgaaggagacccggggctacgg aggggatgcccccttctgcacccgcctcaaccactcctacacaggcatgtgggcgcccgagcgttccgccgaggcgcggg gcaacctcacgcgccctccagggtctggcgaggattgcggatcggtgtccgtggccttcccgatcaccatgctgctcact ggtttcgtgggcaacgcactggccatgctgctcgtgtcgcgcagctaccggcgccgggagagcaagcgcaagaagtcctt cctgctgtgcatcggctggctggcgctcaccgacctggtcgggcagcttctcaccaccccggtcgtcatcgtcgtgtacc tgtccaagcagcgttgggagcacatcgacccgtcggggcggctctgcacctttttcgggctgaccatgactgttttcggg ctctcctcgttgttcatcgccagcgccatggccgtcgagcgggcgctggccatcagggcgccgcactggtatgcgagcca catgaagacgcgtgccacccgcgctgtgctgctcggcgtgtggctggccgtgctcgccttcgccctgctgccggtgctgg gcgtgggccagtacaccgtccagtggcccgggacgtggtgcttcatcagcaccgggcgagggggcaacgggactagctct tcgcataactggggcaaccttttcttcgcctctgcctttgccttcctggggctcttggcgctgacagtcaccttttcctg caacctggccaccattaaggccctggtgtcccgctgccgggccaaggccacggcatctcagtccagtgcccagtggggcc gcatcacgaccgagacggccattcagcttatggggatcatgtgcgtgctgtcggtctgctggtctccgctcctgataatg atgttgaaaatgatcttcaatcagacatcagttgagcactgcaagacacacacggagaagcagaaagaatgcaacttctt cttaatagctgttcgcctggcttcactgaaccagatcttggatccttgggtttacctgctgttaagaaagatccttcttc gaaagttttgccaggtagcaaatgctgtctccagctgctctaatgatggacagaaagggcagcctatctcattatctaat gaaataatacagacagaagcatgaaagaaaacacttaacttgcatgtgcacagcttctggtaacaaatatcgctaaacct tactgtgaatttaggcatctctggcatgccactgtttatgcattgaagtggaatttttggtataaagctaaatggtctta gaagcatagaaaatccctatgtgccaaaagtagtgaaacacaaacaaaggaaaatata taataacagtctagtgttttt gttgagtctgccattcgtagctgaatatgtgattaattatgtgatgaaaactttttttataaatgatcttggtctattgg gg (SEQ ID Nθ:12165) cccgggccagtgagccctggcgccgccgcggccgcggtcccagcagcggagtagggcggcggctgcgccccgcaccatgg ggggcagcccagccccagccgcggtaaacgccgacctccgccgccgcccgcgccgcgtctgccccctcccgctgcggctc tctggacgccatcccctcctcacctcgaagccaacatgaaggagacccggggctacggaggggatgcccccttctgcacc cgcctcaaccactcctacacaggcatgtgggcgcccgagcgttccgccgaggcgcggggcaacctcacgcgccctccagg gtctggcgaggattgcggatcggtgtccgtggccttcccgatcaccatgctgctcactggtttcgtgggcaacgcactgg ccatgctgctcgtgtcgcgcagctaccggcgccgggagagcaagcgcaagaagtccttcctgctgtgcatcggctggctg gcgctcaccgacctggtcgggcagcttctcaccaccccggtcgtcatcgtcgtgtacctgtccaagcagcgttgggagca catcgacccgtcggggcggctctgcacctttttcgggctgaccatgactgttttcgggctctcctcgttgttcatcgcca gcgccatggccgtcgagcgggcgctggccatcagggcgccgcactggtatgcgagccacatgaagacgcgtgccacccgc gctgtgctgctcggcgtgtggctggccgtgctcgccttcgccctgctgccggtgctgggcgtgggccagtacaccgtcca gtggcccgggacgtggtgcttcatcagcaccgggcgagggggcaacgggactagctcttcgcataactggggcaaccttt tcttcgcctctgcctttgccttcctggggctcttggcgctgacagtcaccttttcctgcaacctggccaccattaaggcc ctggtgtcccgctgccgggccaaggccacggcatctcagtccagtgcccagtggggccgcatcacgaccgagacggccat tcagcttatggggatcatgtgcgtgctgtcggtctgctggtctccgctcctgataatgatgttgaaaatgatcttcaatc agacatcagttgagcactgcaagacacacacggagaagcagaaagaatgcaacttcttcttaatagctgttcgcctggct tcactgaaccagatcttggatccttgggtttacctgctgttaagaaagatccttcttcgaaagttttgccagatcaggta ccacacaaacaactatgcatccagctccacctccttaccctgccagtgttcctcaaccttgatgtggagcgaccatttgg aaagataatgaaagaacggagttggacattttattgcaattcctgcttccctgaatttgcatatttcttcccacctgaga aggataattatatattttaatttggattatttcttcatttttatctttttattttaatgattgttttgtcagtaataccc atggagatcaactttattattataatccatgcctctgaatattagattggtttcttggatgggattttgaatatgcattt aagaagttgggaagaatttcacagatgatgattggaggaaaagtgatgaaaagaaagacctgtgttccaggagttttctc caacttcaaacctttacgtgaatcttaaccaaagtggacatctttacatttcatgatagcttgcttttgcaatatgagtt tgaaaaatcagtataagcttatgatggtgaaaagtcaacatattgagagtgataattcaattaataggatatgaacttaa cgatataaaagcaaatgagggcaggagggg (SEQ ID NO: 12166) agagaggaaggcgtggctccctcccgggccagtgagccctggcgccgccgcggccgcggtcccagcagcggagtagggcg gcggctgcgccccgcaccatggggggcagcccagccccagccgcggtaaacgccgacctccgccgccgcccgcgccgcgt ctgccccctcccgctgcggctctctggacgccatcccctcctcacctcgaagccaacatgaaggagacccggggctacgg aggggatgcccccttctgcacccgcctcaaccactcctacacaggcatgtgggcgcccgagcgttccgccgaggcgcggg gcaacctcacgcgccctccagggtctggcgaggattgcggatcggtgtccgtggccttcccgatcaccatgctgctcact ggtttcgtgggcaacgcactggccatgctgctcgtgtcgcgcagctaccggcgccgggagagcaagcgcaagaagtcctt cctgctgtgcatcggctggctggcgctcaccgacctggtcgggcagcttctcaccaccccggtcgtcatcgtcgtgtacc tgtccaagcagcgttgggagcacatcgacccgtcggggcggctctgcacctttttcgggctgaccatgactgttttcggg ctctcctcgttgttcatcgccagcgccatggccgtcgagcgggcgctggccatcagggcgccgcactggtatgcgagcca catgaagacgcgtgccacccgcgctgtgctgctcggcgtgtggctggccgtgctcgccttcgccctgctgccggtgctgg gcgtgggccagtacaccgtccagtggcccgggacgtggtgcttcatcagcaccgggcgagggggcaacgggactagctct tcgcataactggggcaaccttttcttcgcctctgcctttgccttcctggggctcttggcgctgacagtcaccttttcctg caacctggccaccattaaggccctggtgtcccgctgccgggccaaggccacggcatctcagtccagtgcccagtggggcc gcatcacgaccgagacggccattcagcttatggggatcatgtgcgtgctgtcggtctgctggtctccgctcctgataatg atgttgaaaatgatcttcaatcagacatcagttgagcactgcaagacacacacggagaagcagaaagaatgcaacttctt cttaatagctgttcgcctggcttcactgaaccagatcttggatccttgggtttacctgctgttaagaaagatccttcttc gaaagttttgccaggtagcaaatgctgtctccagctgctctaatgatggacagaaagggcagcctatctcattatctaat gaaataatacagacagaagcatgaaagaaaacacttaacttgcatgtgcacagcttctggtaacaaatatcgctaaacct tactgtgaatttaggcatctctggcatgccactgtttat'gcattgaagtggaatttttggtataaagctaaatggtctta gaagcatagaaaatccctatgtgccaaaagtagtgaaacacaaacaaaggaaaatatattaataacagtctagtgttttt gttgagtctgccattcgtagctgaatatgtgattaattatgtgatgaaaactttttttataaatgatcttggtctattgg gg (SEQ ID NO: 12167) agagaggaaggcgtggctccctcccgggccagtgagccctggcgccgccgcggccgcggtcccagcagcggagtagggcg gcggctgcgccccgcaccatggggggcagcccagccccagccgcggtaaacgccgacctccgccgccgcccgcgccgcgt ctgccccctcccgctgcggctctctggacgccatcccctcctcacctcgaagccaacatgaaggagacccggggctacgg aggggatgcccccttctgcacccgcctcaaccactcctacacaggcatgtgggcgcccgagcgttccgccgaggcgcggg gcaacctcacgcgccctccagggtctggcgaggattgcggatcggtgtccgtggccttcccgatcaccatgctgctcact ggtttcgtgggcaacgcactggccatgctgctcgtgtcgcgcagctaccggcgccgggagagcaagcgcaagaagtcctt cctgctgtgcatcggctggctggcgctcaccgacctggtcgggcagcttctcaccaccccggtcgtcatcgtcgtgtacc tgtccaagcagcgttgggagcacatcgacccgtcggggcggctctgcacctttttcgggctgaccatgactgttttcggg ctctcctcgttgttcatcgccagcgccatggccgtcgagcgggcgctggccatcagggcgccgcactggtatgcgagcca catgaagacgcgtgccacccgcgctgtgctgctcggcgtgtggctggccgtgctcgccttcgccctgctgccggtgctgg gcgtgggccagtacaccgtccagtggcccgggacgtggtgcttcatcagcaccgggcgagggggcaacgggactagctct tcgcataactggggcaaccttttcttcgcctctgcctttgccttcctggggctcttggcgctgacagtcaccttttcctg caacctggccaccattaaggccctggtgtcccgctgccgggccaaggccacggcatctcagtccagtgcccagtggggcc gcatcacgaccgagacggccattcagcttatggggatcatgtgcgtgctgtcggtctgctggtctccgctcctgataatg atgttgaaaatgatcttcaatcagacatcagttgagcactgcaagacacacacggagaagcagaaagaatgcaacttctt cttaatagctgttcgcctggcttcactgaaccagatcttggatccttgggtttacctgctgttaagaaagatccttcttc gaaagttttgccaggaggaattttggggaaattaaaacctgcctttctgccaggatcacatcactggaagctccatgact ctctttttgtaaaagaaaa (SEQ ID NO: 12168) gtgcgcggaggggacgagcggctggaccacagccggcgcccgatcaggatctccgcgctgggatcggtggaacttgaggc agcggcggcgcggggcgccatggcacaccgagcggctccgtcttctgctcctcagagagcccggctggcggcctgggatg acaagatgtctggactgcaatcctgcacagttttgagagggagatgacttgagtggttggcttttatctccacaacaatg tccatgaacaattccaaacagctagtgtctcctgcagctgcgcttctttcaaacacaacctgccagacggaaaaccggct ttccgtatttttttcagtaatcttcatgacagtgggaatcttgtcaaacagccttgccatcgccattctcatgaaggcat atcagagatttagacagaagtccaaggcatcgtttctgcttttggccagcggcctggtaatcactgatttctttggccat ctcatcaatggagccatagcagtatttgtatatgcttctgataaagaatggatccgctttgaccaatcaaatgtcctttg cagtatttttggtatctgcatggtgttttctggtctgtgcccacttcttctaggcagtgtgatggccattgagcggtgta ttggagtcacaaaaccaatatttcattctacgaaaattacatccaaacatgtgaaaatgatgttaagtggtgtgtgcttg tttgctgttttcatagctttgctgcccatccttggacatcgagactataaaattcaggcgtcgaggacctggtgtttcta caacacagaagacatcaaagactgggaagatagattttatcttctacttttttcttttctggggctcttagcccttggtg tttcattgttgtgcaatgcaatcacaggaattacacttttaagagttaaatttaaaagtcagcagcacagacaaggcaga tctcatcatttggaaatggtaatccagctcctggcgataatgtgtgtctcctgtatttgttggagcccatttctggttac aatggccaacattggaataaatggaaatcattctctggaaacctgtgaaacaacactttttgctctccgaatggcaacat ggaatcaaatcttagatccttgggtatatattcttctacgaaaggctgtccttaagaatctctataagcttgccagtcaa tgctgtggagtgcatgtcatcagcttacatatttgggagcttagttccattaaaaattccttaaaggttgctgctatttc tgagtcaccagttgcagagaaatcagcaagcacctagcttaataggacagtaaatctgtgtggggctagaacaaaaatta agacatgtttggcaatatttcagttagttaaatacctgtagcctaactggaaaattcaggcttcatcatgtagtttgaag atactattgtcagattcaggttttgaaatttgtcaaataaacaggataactgtacattttcaacttgtttttgccaatgg gaggtagacacaataaaataatgccatgggagtcacactgaaagcaattttgagcttatctgtcttatttatgctttgag tgaatcatctgttgaggtctaatgcctctacttggcctatttgccagagaacatcttaatgcagcctgcatagtgaaatg gttattttgagatcaccgctctgtagctaacccttataaactaggctcagtaaaataaagcactcttattttttgatctg gcctattttgcccctcattgtgtagcctcaattaacacatgcatggtcatgacacccagaattcatgatggtttgttata acaacctctgcatattccaggtctggcagacaggttgcctgaccctgcaatcctatctagaatgggcccattcttgtcac atttgacaaataggactgcctacatttattattatgaaggtcgattgttgttggaagtgttttttcatgtcatagattag caattttcaaataattattttttctctgaaaattttgtgtgtgattgcacaataaataatttttagagaaacaaaggctc tttctcagcacattgatgggcaactagaattacagcagtttcaaactctaccatggataatgcaaacaaaccgaagctac atgccaatgataggtgcaaagaatattggcaaaaggtgctttaccttgagccattatttgtgtcagagaacaaaagaaac agaatcaatatataaattcaaagactatctgcagctagtgtgtttcttctttacacacatatacacacagacatcagaaa attctgttgagagcaggttcattaaatttgtaagatggcatattctaaagcctgtgctaccagtactaagaggggaagac tggcaatttgccaagcacttggggattattataacaattaactaggagatcaagagataataatctctccccaaattttc caataataattgag (SEQ ID NO: 12169) ggcacagacgcacgggacaggagagcctgggcaagactggagagcccagacctgggatggcggattcgtgcaggaacctc acctacgtgcggggctcggtggggccggccaccagcaccctgatgttcgtggccggtgtggtgggcaacgggctggccct gggcatcctgagcgcacggcgaccggcgcgcccctcggccttcgcggtgctggtcaccggactggcggccaccgacctgc tgggcaccagcttcctgagcccggccgtgttcgtggcctatgcgcgcaacagctccctgctgggcctggcccgaggcggc cccgccctgtgcgatgccttcgccttcgccatgaccttcttcggcctggcgtccatgctcatcctctttgccatggccgt ggagcgctgcctggcgctgagccacccctacctctacgcgcagctggacgggccccgctgcgcccgcctggcgctgccag ccatctacgccttctgcgtcctcttctgcgcgctgcccctgctgggcctgggccaacaccagcagtactgccccggcagc tggtgcttcctccgcatgcgctgggcccagccgggcggcgccgccttctcgctggcctacgccggcctggtggccctgct ggtggctgccatcttcctctgcaacggctcggtcaccctcagcctctgccgcatgtaccgccagcagaagcgccaccagg gctctctgggtccacggccgcgcaccggagaggacgaggtggaccacctgatcctgctggccctcatgacagtggtcatg gccgtgtgctccctgcctctcacgatccgctgcttcacccaggctgtcgcccctgacagcagcagtgagatgggggacct ccttgccttccgcttctacgccttcaaccccatcctggacccctgggtcttcatccttttccgcaaggctgtcttccagc gactcaagctctgggtctgctgcctgtgcctcgggcctgcccacggagactcgcagacacccctttcccagctcgcctcc gggaggagggacccaagggccccctctgctcctgtgggaaaggaggggagctgcgtgcctttgtcggcttggggcgaggg gcaggtggagcccttgcctcccacacagcagtccagcggcagcgccgtgggaacgtcgtccaaagcagaagccagcgtcg cctgctccctctgctgacatttcaagctgaccctgtgatctctgccctgtcttcgggcgacaggagccagaaaatcaggg acatggctgatggctgcggatgctggaaccttggcccccaaactctggggccgatcagctgctgtttctctgcggcaggg cagtcgctgctggctctgggaagagagtgagggacagaggaaacgtttatcctggag (SEQ ID NO: 12170) gctgtgcaacctcggcgccatgcgcaacctctatgcgatgcaccggcggctgcagcggcacccgcgctcctgcaccaggg actgtgccgagccgcgcgcggacgggagggaagcgtcccctcagcccctggaggagctggatcacctcctgctgctggcg ctgatgaccgtgctcttcactatgtgttctctgcccgtaatttatcgcgcttactatggagcatttaaggatgtcaagga gaaaaacaggacctctgaagaagcagaagacctccgagccttgcgatttctatctgtgatttcaattgtggacccttgga tttttatcattttcagatctccagtatttcggatattttttcacaagattttcattagacctcttaggtacaggagccgg tgcagcaattccactaacatggaatccagtctgtgacagtgtttttcactctgtggtaagctgaggaatatgtcacattt tcagtcaaagaaccagaattctggctattttcctcctgccgttccgactcggcaccagagtctgtctctactgagaacgc agcgcgtcagggccgagctcttcactggcctgctccgcgctcttcaatgccagcgccaggcgctcaccctgcagagcgtc ccgcctctcaaagaggggtgtgacccgcgagtttagataggaggttcctgccgtggggaacaccccgccgccctcggagc tttttctgtggcgcagcttctccgcccgagccgcgcgcggagctgccgggggctccttagcacccgggcgccggggccct cgcccttccgcagccttcactccagccctctgctcccgcacgccatgaagtcgccgttctaccgctgccagaacaccacc tctgtggaaaaaggcaactcggcggtgatgggcggggtgctcttcagcaccggcctcctgggcaacctgctggccctggg gctgctggcgcgctcggggctggggtggtgctcgcggcgtccactgcgcccgctgccctcggtcttctacatgctggtgt gtggcctgacggtcaccgacttgctgggcaagtgcctcctaagcccggtggtgctggctgcctacgctcagaaccggagt ctgcgggtgcttgcgcccgcattggacaactcgttgtgccaagccttcgccttcttcatgtccttctttgggctctcctc » gacactgcaactcctggccatggcactggagtgctggctctccctagggcaccctttcttctaccgacggcacatcaccc tgcgcctgggcgcactggtggccccggtggtgagcgccttctccctggctttctgcgcgctacctttcatgggcttcggg aagttcgtgcagtactgccccggcacctggtgctttatccagatggtccacgaggagggctcgctgtcggtgctggggta ctctgtgctctactccagcctcatggcgctgctggtcctcgccaccgtgctgtgcaacctcggcgccatgcgcaacctct atgcgatgcaccggcggctgcagcggcacccgcgctcctgcaccagggactgtgccgagccgcgcgcggacgggagggaa gcgtcccctcagcccctggaggagctggatcacctcctgctgctggcgctgatgaccgtgctcttcactatgtgttctct gcccgtaattgtgagtccccgggccccgagggggccgccgtcggcgcgctgggtgcgggaagggggctctggatttcggt ccctcccctttttcctctgagtctcggaacgctccagctctcagaccctcttcctcccaggtaaaggccgggagaggagg gcgcatctcttttccaggcaccccaccatgggcaatgcctccaatgactcccagtctgaggactgcgagacgcgacagtg gcttcccccaggcgaaagcccagccatcagctccgtcatgttctcggccggggtgctggggaacctcatagcactggcgc tgctggcgcgccgctggcggggggacgtggggtgcagcgccggccgcaggagctccctctccttgttccacgtgctggtg accgagctggtgttcaccgacctgctcgggacctgcctcatcagcccagtggtactggcttcgtacgcgcggaaccagac cctggtggcactggcgcccgagagccgcgcgtgcacctacttcgctttcgccatgaccttcttcagcctggccacgatgc tcatgctcttcgccatggccctggagcgctacctctcgatcgggcacccctacttctaccagcgccgcgtctcggcctcc gggggcctggccgtgctgcctgtcatctatgcagtctccctgctcttctgctcgctgccgctgctggactatgggcagta cgtccagtactgccccgggacctggtgcttcatccggcacgggcggaccgcttacctgcagctgtacgccaccctgctgc tgcttctcattgtctcggtgctcgcctgcaacttcagtgtcattctcaacctcatccgcatgcaccgccgaagccggaga agccgctgcggaccttccctgggcagtggccggggcggccccggggcccgcaggagaggggaaagggtgtccatggcgga ggagacggaccacctcattctcctggctatcatgaccatcaccttcgccgtctgctccttgcctttcacgatttttgcat atatgaatgaaacctcttcccgaaaggaaaaatgggacctccaagctcttaggtttttatcaattaattcaataattgac ccttgggtctttgccatccttaggcctcctgttctgagactaatgcgttcagtcctctgttgtcggatttcattaagaac acaagatgcaacacaaacttcctgttctacacagtcagatgccagtaaacaggctgacctttgaggtcagtagtttaaaa gttcttagttatatagcatctggaagatcattttgaaattgttccctggagaaatgaaaacagtgtgtaaacaaaatgaa gctgccctaataaaaaggagtatacaaacatttaagctgtggtcaaggctacagatgtgctgacaaggcacttcatgtaa agtgtcagaaggagctacaaaacctaccctcaatgagcatggtacttggcctttggaggaacaatcggctgcattgaaga tccagctgcctattgatttaagctttcctgttgaatgacaaagtatgtggttttgtaatttgtttgaaaccccaaacagt gactgtactttctattttaatcttgctactaccgttatacacatatagtgtacagccagaccagattaaacttcatatgt aatctctaggaagtcaatatgtggaagcaaccaagcctgctgtcttgtgatcacttagcgaaccctttatttgaacaatg aagttgaaaatcataggcaccttttactgtgatgtttgtgtatgtgggagtactctcatcactacagtattactcttaca agagtggactcagtgggttaacatcagttttgtttactcatcctccaggaactgcaggtcaagttgtcaggttatttatt ttataatgtccatatgctaatagtgatcaagaagactttaggaatggttctctcaacaagaaataatagaaatgtctcaa ggcagttaattctcattaatactcttattatcctatttctgggggaggatgtacgtggccatgtatgaagccaaatatta ggcttaaaaactgaaaaatctggttcattcttcagatatactggaacccttttaaagttgatattggggccatgagtaaa atagattttataagatgactgtgttgtaccaaaattcatctgtctatattttatttaggggaacatggtttgactcatct tatatgggaaaccatgtagcagtgagtcatatcttaatatatttctaaatgtttggcatgtaaatgtaaactcagcatca aaatatttcagtgaatttgcactgtttaatcatagttactgtgtaaactcatctgaaatgttacaaaaataaactataaa acaagagaggaaggcgtggctccctcccgggccagtgagccctggcgccgccgcggccgcggtcccagcagcggagtagg gcggcggctgcgccccgcaccatggggggcagcccagccccagccgcggtaaacgccgacctccgccgccgcccgcgccg cgtctgccccctcccgctgcggctctctggacgccatcccctcctcacctcgaagccaacatgaaggagacccggggcta cggaggggatgcccccttctgcacccgcctcaaccactcctacacaggcatgtgggcgcccgagcgttccgccgaggcgc ggggcaacctcacgcgccctccagggtctggcgaggattgcggatcggtgtccgtggccttcccgatcaccatgctgctc actggtttcgtgggcaacgcactggccatgctgctcgtgtcgcgcagctaccggcgccgggagagcaagcgcaagaagtc cttcctgctgtgcatcggctggctggcgctcaccgacctggtcgggcagcttctcaccaccccggtcgtcatcgtcgtgt acctgtccaagcagcgttgggagcacatcgacccgtcggggcggctctgcacctttttcgggctgaccatgactgttttc gggctctcctcgttgttc^'atcgccagcgccatggccgtcgagcgggcgctggccatcagggcgccgcactggtatgcgag ccacatgaagacgcgtgccacccgcgctgtgctgctcggcgtgtggctggccgtgctcgccttcgccctgctgccggtgc tgggcgtgggccagtacaccgtccagtggcccgggacgtggtgcttcatcagcaccgggcgagggggcaacgggactagc tcttcgcataactggggcaaccttttcttcgcctctgcctttgccttcctggggctcttggcgctgacagtcaccttttc ctgcaacctggccaccattaaggccctggtgtcccgctgccgggccaaggccacggcatctcagtccagtgcccagtggg gccgcatcacgaccgagacggccattcagcttatggggatcatgtgcgtgctgtcggtctgctggtctccgctcctgata atgatgttgaaaatgatcttcaatcagacatcagttgagcactgcaagacacacacggagaagcagaaagaatgcaactt cttcttaatagctgttcgcctggcttcactgaaccagatcttggatccttgggtttacctgctgttaagaaagatccttc ttcgaaagttttgccaggtagcaaatgctgtctccagctgctctaatgatggacagaaagggcagcctatctcattatct aatgaaataatacagacagaagcatgaaagaaaacacttaacttgcatgtgcacagcttctggtaacaaatatcgctaaa ccttactgtgaatttaggcatctctggcatgccactgtttatgcattgaagtggaatttttggtataaagctaaatggtc ttagaagcatagaaaatccctatgtgccaaaagtagtgaaacacaaacaaaggaaaatatattaataacagtctagtgtt tttgttgagtctgccattcgtagctgaatatgtgattaattatgtgatgaaaactttttttataaatgatcttggtctat tggggcccgggccagtgagccctggcgccgccgcggccgcggtcccagcagcggagtagggcggcggctgcgccccgcac catggggggcagcccagccccagccgcggtaaacgccgacctccgccgccgcccgcgccgcgtctgccccctcccgctgc ggctctctggacgccatcccctcctcacctcgaagccaacatgaaggagacccggggctacggaggggatgcccccttct gcacccgcctcaaccactcctacacaggcatgtgggcgcccgagcgttccgccgaggcgcggggcaacctcacgcgccct ccagggtctggcgaggattgcggatcggtgtccgtggccttcccgatcaccatgctgctcactggtttcgtgggcaacgc actggccatgctgctcgtgtcgcgcagctaccggcgccgggagagcaagcgcaagaagtccttcctgctgtgcatcggct ggctggcgctcaccgacctggtcgggcagcttctcaccaccccggtcgtcatcgtcgtgtacctgtccaagcagcgttgg gagcacatcgacccgtcggggcggctctgcacctttttcgggctgaccatgactgttttcgggctctcctcgttgttcat cgccagcgccatggccgtcgagcgggcgctggccatcagggcgccgcactggtatgcgagccacatgaagacgcgtgcca cccgcgctgtgctgctcggcgtgtggctggccgtgctcgccttcgccctgctgccggtgctgggcgtgggccagtacacc gtccagtggcccgggacgtggtgcttcatcagcaccgggcgagggggcaacgggactagctcttcgcataactggggcaa ccttttcttcgcctctgcctttgccttcctggggctcttggcgctgacagtcaccttttcctgcaacctggccaccatta aggccctggtgtcccgctgccgggccaaggccacggcatctcagtccagtgcccagtggggccgcatcacgaccgagacg gccattcagcttatggggatcatgtgcgtgctgtcggtctgctggtctccgctcctgataatgatgttgaaaatgatctt caatcagacatcagttgagcactgcaagacacacacggagaagcagaaagaatgcaacttcttcttaatagctgttcgcc tggcttcactgaaccagatcttggatccttgggtttacctgctgttaagaaagatccttcttcgaaagttttgccagatc aggtaccacacaaacaactatgcatccagctccacctccttaccctgccagtgttcctcaaccttgatgtggagcgacca tttggaaagataatgaaagaacggagttggacattttattgcaattcctgcttccctgaatttgcatatttcttcccacc tgagaaggataattatatattttaatttggattatttcttcatttttatctttttattttaatgattgttttgtcagtaa tacccatggagatcaactttattattataatccatgcctctgaatattagattggtttcttggatgggattttgaatatg catttaagaagttgggaagaatttcacagatgatgattggaggaaaagtgatgaaaagaaagacctgtgttccaggagtt ttctccaacttcaaacctttacgtgaatcttaaccaaagtggacatctttacatttcatgatagcttgcttttgcaatat gagtttgaaaaatcagtataagcttatgatggtgaaaagtcaacatattgagagtgataattcaattaataggatatgaa cttaacgatataaaagcaaatgagggcaggaggggagagaggaaggcgtggctccctcccgggccagtgagccctggcgc cgccgcggccgcggtcccagcagcggagtagggcggcggctgcgccccgcaccatggggggcagcccagccccagccgcg gtaaacgccgacctccgccgccgcccgcgccgcgtctgccccctcccgctgcggctctctggacgccatcccctcctcac ctcgaagccaacatgaaggagacccggggctacggaggggatgcccccttctgcacccgcctcaaccactcctacacagg catgtgggcgcccgagcgttccgccgaggcgcggggcaacctcacgcgccctccagggtctggcgaggattgcggatcgg tgtccgtggccttcccgatcaccatgctgctcactggtttcgtgggcaacgcactggccatgctgctcgtgtcgcgcagc taccggcgccgggagagcaagcgcaagaagtccttcctgctgtgcatcggctggctggcgctcaccgacctggtcgggca gcttctcaccaccccggtcgtcatcgtcgtgtacctgtccaagcagcgttgggagcacatcgacccgtcggggcggctct gcacctttttcgggctgaccatgactgttttcgggctctcctcgttgttcatcgccagcgccatggccgtcgagcgggcg ctggccatcagggcgccgcactggtatgcgagccacatgaagacgcgtgccacccgcgctgtgctgctcggcgtgtggct ggccgtgctcgccttcgccctgctgccggtgctgggcgtgggccagtacaccgtccagtggcccgggacgtggtgcttca tcagcaccgggcgagggggcaacgggactagctcttcgcataactggggcaaccttttcttcgcctctgcctttgccttc ctggggctcttggcgctgacagtcaccttttcctgcaacctggccaccattaaggccctggtgtcccgctgccgggccaa ggccacggcatctcagtccagtgcccagtggggccgcatcacgaccgagacggccattcagcttatggggatcatgtgcg tgctgtcggtctgctggtctccgctcctgataatgatgttgaaaatgatcttcaatcagacatcagttgagcactgcaag acacacacggagaagcagaaagaatgcaacttcttcttaatagctgttcgcctggcttcactgaaccagatcttggatcc ttgggtttacctgctgttaagaaagatccttcttcgaaagttttgccaggtagcaaatgctgtctccagctgctctaatg atggacagaaagggcagcctatctcattatctaatgaaataatacagacagaagcatgaaagaaaacacttaacttgcat gtgcacagcttctggtaacaaatatcgctaaaccttactgtgaatttaggcatctctggcatgccactgtttatgcattg aagtggaatttttggtataaagctaaatggtcttagaagcatagaaaatccctatgtgccaaaagtagtgaaacacaaac aaaggaaaatatattaataacagtctagtgtttttgttgagtctgccattcgtagctgaatatgtgattaattatgtgat gaaaactttttttataaatgatcttggtctattggggagagaggaaggcgtggctccctcccgggccagtgagccctggc gccgccgcggccgcggtcccagcagcggagtagggcggcggctgcgccccgcaccatggggggcagcccagccccagccg cggtaaacgccgacctccgccgccgcccgcgccgcgtctgccccctcccgctgcggctctctggacgccatcccctcctc acctcgaagccaacatgaaggagacccggggctacggaggggatgcccccttctgcacccgcctcaaccactcctacaca ggcatgtgggcgcccgagcgttccgccgaggcgcggggcaacctcacgcgccctccagggtctggcgaggattgcggatc ggtgtccgtggccttcccgatcaccatgctgctcactggtttcgtgggcaacgcactggccatgctgctcgtgtcgcgca gctaccggcgccgggagagcaagcgcaagaagtccttcctgctgtgcatcggctggctggcgctcaccgacctggtcggg cagcttctcaccaccccggtcgtcatcgtcgtgtacctgtccaagcagcgttgggagcacatcgacccgtcggggcggct ctgcacctttttcgggctgaccatgactgttttcgggctctcctcgttgttcatcgccagcgccatggccgtcgagcggg cgctggccatcagggcgccgcactggtatgcgagccacatgaagacgcgtgccacccgcgctgtgctgctcggcgtgtgg ctggccgtgctcgccttcgccctgctgccggtgctgggcgtgggccagtacaccgtccagtggcccgggacgtggtgctt catcagcaccgggcgagggggcaacgggactagctcttcgcataactggggcaaccttttcttcgcctctgcctttgcct tcctggggctcttggcgctgacagtcaccttttcctgcaacctggccaccattaaggccctggtgtcccgctgccgggcc aaggccacggcatctcagtccagtgcccagtggggccgcatcacgaccgagacggccattcagcttatggggatcatgtg cgtgctgtcggtctgctggtctccgctcctgataatgatgttgaaaatgatcttcaatcagacatcagttgagcactgca agacacacacggagaagcagaaagaatgcaacttcttcttaatagctgttcgcctggcttcactgaaccagatcttggat ccttgggtttacctgctgttaagaaagatccttcttcgaaagttttgccaggaggaattttggggaaattaaaacctgcc tttctgccaggatcacatcactggaagctccatgactctctttttgtaaaagaaaagtgcgcggaggggacgagcggctg gaccacagccggcgcccgatcaggatctccgcgctgggatcggtggaacttgaggcagcggcggcgcggggcgccatggc acaccgagcggctccgtcttctgctcctcagagagcccggctggcggcctgggatgacaagatgtctggactgcaatcct gcacagttttgagagggagatgacttgagtggttggcttttatctccacaacaatgtccatgaacaattccaaacagcta gtgtctcctgcagctgcgcttctttcaaacacaacctgccagacggaaaaccggctttccgtatttttttcagtaatctt catgacagtgggaatcttgtcaaacagccttgccatcgccattctcatgaaggcatatcagagatttagacagaagtcca aggcatcgtttctgcttttggccagcggcctggtaatcactgatttctttggccatctcatcaatggagccatagcagta tttgtatatgcttctgataaagaatggatccgctttgaccaatcaaatgtcctttgcagtatttttggtatctgcatggt gttttctggtctgtgcccacttcttctaggcagtgtgatggccattgagcggtgtattggagtcacaaaaccaatatttc attctacgaaaattacatccaaacatgtgaaaatgatgttaagtggtgtgtgcttgtttgctgttttcatagctttgctg cccatccttggacatcgagactataaaattcaggcgtcgaggacctggtgtttctacaacacagaagacatcaaagactg ggaagatagattttatcttctacttttttcttttctggggctcttagcccttggtgtttcattgttgtgcaatgcaatca caggaattacacttttaagagttaaatttaaaagtcagcagcacagacaaggcagatctcatcatttggaaatggtaatc cagctcctggcgataatgtgtgtctcctgtatttgttggagcccatttctggttacaatggccaacattggaataaatgg aaatcattctctggaaacctgtgaaacaacactttttgctctccgaatggcaacatggaatcaaatcttagatccttggg tatatattcttctacgaaaggctgtccttaagaatctctataagcttgccagtcaatgctgtggagtgcatgtcatcagc ttacatatttgggagcttagttccattaaaaattccttaaaggttgctgctatttctgagtcaccagttgcagagaaatc agcaagcacctagcttaataggacagtaaatctgtgtggggctagaacaaaaattaagacatgtttggcaatatttcagt tagttaaatacctgtagcctaactggaaaattcaggcttcatcatgtagtttgaagatactattgtcagattcaggtttt gaaatttgtcaaataaacaggataactgtacattttcaacttgtttttgccaatgggaggtagacacaataaaataatgc catgggagtcacactgaaagcaattttgagcttatctgtcttatttatgctttgagtgaatcatctgttgaggtctaatg cctctacttggcctatttgccagagaacatcttaatgcagcctgcatagtgaaatggttattttgagatcaccgctctgt agctaacccttataaactaggctcagtaaaataaagcactcttattttttgatctggcctattttgcccctcattgtgta gcctcaattaacacatgcatggtcatgacacccagaattcatgatggtttgttataacaacctctgcatattccaggtct ggcagacaggttgcctgaccctgcaatcctatctagaatgggcccattcttgtcacatttgacaaataggactgcctaca tttattattatgaaggtcgattgttgttggaagtgttttttcatgtcatagattagcaattttcaaataattattttttc tctgaaaattttgtgtgtgattgcacaataaataatttttagagaaacaaaggctctttctcagcacattgatgggcaac tagaattacagcagtttcaaactctaccatggataatgcaaacaaaccgaagctacatgccaatgataggtgcaaagaat attggcaaaaggtgctttaccttgagccattatttgtgtcagagaacaaaagaaacagaatcaatatataaattcaaaga ctatctgcagctagtgtgtttcttctttacacacatatacacacagacatcagaaaattctgttgagagcaggttcatta aatttgtaagatggcatattctaaagcctgtgctaccagtactaagaggggaagactggcaatttgccaagcacttgggg attattataacaattaactaggagatcaagagataataatctctccccaaattttccaataataattgagggcacagacg cacgggacaggagagcctgggcaagactggagagcccagacctgggatggcggattcgtgcaggaacctcacctacgtgc ggggctcggtggggccggccaccagcaccctgatgttcgtggccggtgtggtgggcaacgggctggccctgggcatcctg agcgcacggcgaccggcgcgcccctcggccttcgcggtgctggtcaccggactggcggccaccgacctgctgggcaccag cttcctgagcccggccgtgttcgtggcctatgcgcgcaacagctccctgctgggcctggcccgaggcggccccgccctgt gcgatgccttcgccttcgccatgaccttcttcggcctggcgtccatgctcatcctctttgccatggccgtggagcgctgc ctggcgctgagccacccctacctctacgcgcagctggacgggccccgctgcgcccgcctggcgctgccagccatctacgc cttctgcgtcctcttctgcgcgctgcccctgctgggcctgggccaacaccagcagtactgccccggcagctggtgcttcc tccgcatgcgctgggcccagccgggcggcgccgccttctcgctggcctacgccggcctggtggccctgctggtggctgcc atcttcctctgcaacggctcggtcaccctcagcctctgccgcatgtaccgccagcagaagcgccaccagggctctctggg tccacggccgcgcaccggagaggacgaggtggaccacctgatcctgctggccctcatgacagtggtcatggccgtgtgct ccctgcctctcacgatccgctgcttcacccaggctgtcgcccctgacagcagcagtgagatgggggacctccttgccttc cgcttctacgccttcaaccccatcctggacccctgggtcttcatccttttccgcaaggctgtcttccagcgactcaagct ctgggtctgctgcctgtgcctcgggcctgcccacggagactcgcagacacccctttcccagctcgcctccgggaggaggg acccaagggccccctctgctcctgtgggaaaggaggggagctgcgtgcctttgtcggcttggggcgaggggcaggtggag cccttgcctcccacacagcagtccagcggcagcgccgtgggaacgtcgtccaaagcagaagccagcgtcgcctgctccct ctgctgacatttcaagctgaccctgtgatctctgccctgtcttcgggcgacaggagccagaaaatcagggacatggctga tggctgcggatgctggaaccttggcccccaaactctggggccgatcagctgctgtttctctgcggcagggcagtcgctgc tggctctgggaagagagtgagggacagaggaaacgtttatcctggag (SEQ ID NO: 12171) gctttctcctagggactgtgaggggcgcttctgactttggacttgagcactgcctgggacctgtgctgagagagcgctag catgtctcagtggaatcaagtccaacagttagaaatcaagtttttggagcaggtggatcaattctatgatgacaactttc ccatggaaattcggcatctgttggcccaatggattgaaaatcaagactgggaggcagcttctaacaatgaaaccatggca acgattcttcttcaaaacttgttaatacaactggatgaacagttaggtcgtgtttccaaagagaaaaacctactcttgat acacaatctaaaaagaattaggaaggtccttcagggaaaatttcatggaaatccaatgcatgtagctgtggttatttcaa actgtttaagggaagagaggagaatattggctgcagccaacatgcctgtccaggggcctctagagaaatccttacaaagt tcttcagtttcagaaagacagaggaatgtggagcacaaagtggctgccattaaaaacagtgtgcagatgacagaacaaga taccaaatacttagaagatctgcaagacgaatttgactacaggtataaaacaattcagacaatggatcagagtgacaaga atagtgccatggtgaatcaggaagttttgacactgcaggaaatgcttaacagcctcgatttcaagagaaaggaggctctc agtaaaatgacccaaatcatccatgagacagacctgttaatgaacaccatgctcatagaagagctgcaagactggaagcg gcggcagcaaatcgcctgcatcgggggtccactccacaatgggctcgaccagcttcagaactgctttacactattggcag aaagtcttttccaactgagaaggcaattggagaaactagaggagcaatctaccaaaatgacatatgaaggtgatcccatt ccaatgcaaagaactcacatgctagaaagagtcaccttcttgatctacaaccttttcaagaactcatttgtggttgagcg acagccatgtatgccaacccaccctcagaggccgttggtacttaaaaccctaattcagttcactgtaaaactaaggctac taataaaattgccagaactaaactatcaggtaaaggttaaggcatcaattgacaagaatgtttcaactctaagcaaccga agatttgtactttgtggaactaatgtcaaagccatgtctattgaagaatcttccaatgggagtctctcagtagaatttcg acatttgcaaccaaaggaaatgaagtccagtgctggaggtaaaggaaatgagggctgtcacatggtgactgaagaacttc attccataacgtttgaaacacagatctgcctctatggcctgaccatagatttggagaccagctcattgcctgtggtgatg atttccaatgtcagtcagttacctaatgcttgggcatccatcatttggtacaacgtgtcaaccaacgattcccagaactt ggttttctttaataatcctccacctgccacattgagtcaactactggaggtgatgagctggcagttttcatcgtacgttg gtcgtggtcttaactcagatcaactccatatgctggcagagaagcttacagtccaatctagctacagtgatggtcacctc acctgggccaagttctgcaaggaacatttacctggtaaatcatttaccttttggacatggcttgaagcaatattggatct aattaagaaacacattcttcccctttggattgatgggtatgtcatgggctttgttagcaaagagaaggaacggctgttgc taaaggataaaatgcctggcacctttttattaagattcagtgaaagccatctcggaggaataactttcacctgggtggac cattctgaaagtggggaagtgagattccactctgtagaaccctacaataaaggccggttgtctgctctgccattcgctga catcctgcgagactacaaagttattatggctgaaaacattcctgaaaaccctctgaagtacctatatcctgacattccca aagacaaagccttcggtaaacactacagctctcagccttgcgaagtttcaagaccaacagaaaggggtgacaaaggttat gttccttctgtttttatccccatctcaacaatccgaagtgattcaacagagccacattctccatcagaccttcttcccat gtctccaagtgtgtatgcggtgttgagagaaaacctgagtcccacaacaattgaaactgcaatgaagtctccttattctg ctgaatgacaggataaactctgacgcaccaagaaaggaagcaaatgaaaaagtttaaagactgttctttgcccaataacc acattttatttcttcagctttgtaaataccaggttctaggaaatgtttgacatctgaagctctcttcacactcccgtggc actcctcaattgggagtgttgtgactgaaatgcttgaaaccaaagcttcagataaacttgcaagataagacaactttaag aaaccagtgttaataacaatattaacag (SEQ ID Nθ:12172) gctttctcctagggactgtgaggggcgcttctgactttggacttgagcactgcctgggacctgtgctgagagagcgctag catgtctcagtggaatcaagtccaacagttagaaatcaagtttttggagcaggtggatcaattctatgatgacaactttc ccatggaaattcggcatctgttggcccaatggattgaaaatcaagactgggaggcagcttctaacaatgaaaccatggca acgattcttcttcaaaacttgttaatacaactggatgaacagttaggtcgtgtttccaaagagaaaaacctactcttgat acacaatctaaaaagaattaggaaggtccttcagggaaaatttcatggaaatccaatgcatgtagctgtggttatttcaa actgtttaagggaagagaggagaatattggctgcagccaacatgcctgtccaggggcctctagagaaatccttacaaagt tcttcagtttcagaaagacagaggaatgtggagcacaaagtggctgccattaaaaacagtgtgcagatgacagaacaaga taccaaatacttagaagatctgcaagacgaatttgactacaggtataaaacaattcagacaatggatcagagtgacaaga atagtgccatggtgaatcaggaagttttgacactgcaggaaatgcttaacagcctcgatttcaagagaaaggaggctctc agtaaaatgacccaaatcatccatgagacagacctgttaatgaacaccatgctcatagaagagctgcaagactggaagcg gcggcagcaaatcgcctgcatcgggggtccactccacaatgggctcgaccagcttcagaactgctttacactattggcag aaagtcttttccaactgagaaggcaattggagaaactagaggagcaatctaccaaaatgacatatgaaggtgatcccatt ccaatgcaaagaactcacatgctagaaagagtcaccttcttgatctacaaccttttcaagaactcatttgtggttgagcg acagccatgtatgccaacccaccctcagaggccgttggtacttaaaaccctaattcagttcactgtaaaactaaggctac taataaaattgccagaactaaactatcaggtaaaggttaaggcatcaattgacaagaatgtttcaactctaagcaaccga agatttgtactttgtggaactaatgtcaaagccatgtctattgaagaatcttccaatgggagtctctcagtagaatttcg acatttgcaaccaaaggaaatgaagtccagtgctggaggtaaaggaaatgagggctgtcacatggtgactgaagaacttc attccataacgtttgaaacacagatctgcctctatggcctgaccatagatttggagaccagctcattgcctgtggtgatg atttccaatgtcagtcagttacctaatgcttgggcatccatcatttggtacaacgtgtcaaccaacgattcccagaactt ggttttctttaataatcctccacctgccacattgagtcaactactggaggtgatgagctggcagttttcatcgtacgttg gtcgtggtcttaactcagatcaactccatatgctggcagagaagcttacagtccaatctagctacagtgatggtcacctc acctgggccaagttctgcaaggaacatttacctggtaaatcatttaccttttggacatggcttgaagcaatattggatct aattaagaaacacattcttcccctttggattgatgggtatgtcatgggctttgttagcaaagagaaggaacggctgttgc taaaggataaaatgcctggcacctttttattaagattcagtgaaagccatctcggaggaataactttcacctgggtggac cattctgaaagtggggaagtgagattccactctgtagaaccctacaataaaggccggttgtctgctctgccattcgctga catcctgcgagactacaaagtta tatggctgaaaacattcctgaaaaccctctgaagtacctatatcctgacattccca aagacaaagccttcggtaaacactacagctctcagccttgcgaagtttcaagaccaacagaaaggggtgacaaaggttat gttccttctgtttttatccccatctcaacaatccgaagtgattcaacagagccacattctccatcagaccttcttcccat gtctccaagtgtgtatgcggtgttgagagaaaacctgagtcccacaacaattgaaactgcaatgaagtctccttattctg ctgaatgacaggataaactctgacgcaccaagaaaggaagcaaatgaaaaagtttaaagactgttctttgcccaataacc acattttatttcttcagctttgtaaataccaggttctaggaaatgtttgacatctgaagctctcttcacactcccgtggc actcctcaattgggagtgttgtgactgaaatgcttgaaaccaaagcttcagataaacttgcaagataagacaactttaag aaaccagtgttaataacaatattaacag (SEQ ID NO: 12173) atcttatttttctttttggtggtggtggtggaaggggggaggtgctagcagggccagccttgaactcgctggacagagct acagacctatggggcctggaagtgcccgctgagaaagggagaagacagcagaggggttgccgaggcaacctccaagtccc agatcatgtctctgtggggtctggtctccaagatgcccccagaaaaagtgcagcggctctatgtcgactttccccaacac ctgcggcatcttctgggtgactggctggagagccagccctgggagttcctggtcggctccgacgccttctgctgcaactt ggctagtgccctactttcagacactgtccagcaccttcaggcctcggtgggagagcagggggaggggagcaccatcttgc aacacatcagcacccttgagagcatatatcagagggaccccctgaagctggtggccactttcagacaaatacttcaagga gagaaaaaagctgttatggaacagttccgccacttgccaatgcctttccactggaagcaggaagaactcaagtttaagac aggcttgcggaggctgcagcaccgagtaggggagatccaccttctccgagaagccctgcagaagggggctgaggctggcc aagtgtctctgcacagcttgatagaaactcctgctaatgggactgggccaagtgaggccctggccatgctactgcaggag accactggagagctagaggcagccaaagccctagtgctgaagaggatccagatttggaaacggcagcagcagctggcagg gaatggcgcaccgtttgaggagagcctggccccactccaggagaggtgtgaaagcctggtggacatttattcccagctac agcaggaggtaggggcggctggtggggagcttgagcccaagacccgggcatcgctgactggccggctggatgaagtcctg agaaccctcgtcaccagttgcttcctggtggagaagcagcccccccaggtactgaagactcagaccaagttccaggctgg agttcgattcctgttgggcttgaggttcctgggggccccagccaagcctccgctggtcagggccgacatggtgacagaga agcaggcgcgggagctgagtgtgcctcagggtcctggggctggagcagaaagcactggagaaatcatcaacaacactgtg cccttggagaacagcattcctgggaactgctgctctgccctgttcaagaacctgcttctcaagaagatcaagcggtgtga gcggaagggcactgagtctgtcacagaggagaagtgcgctgtgctcttctctgccagcttcacacttggccccggcaaac tccccatccagctccaggccctgtctctgcccctggtggtcatcgtccatggcaaccaagacaacaatgccaaagccact atcctgtgggacaatgccttctctgagatggaccgcgtgccctttgtggtggctgagcgggtgccctgggagaagatgtg tgaaactctgaacctgaagttcatggctgaggtggggaccaaccgggggctgctcccagagcacttcctcttcctggccc agaagatcttcaatgacaacagcctcagtatggaggccttccagcaccgttctgtgtcctggtcgcagttcaacaaggag a cctgctgggccgtggcttcaccttttggcagtggtttgatggtgtcctggacctcaccaaacgctgtctccggagcta ctggtctgaccggctgatcattggcttcatcagcaaacagtacgttactagccttcttctcaatgagcccgacggaacct ttctcctccgcttcagcgactcagagattgggggcatcaccattgcccatgtcatccggggccaggatggctctccacag atagagaacatccagccattctctgccaaagacctgtccattcgctcactgggggaccgaatccgggatcttgctcagct caaaaatctctatcccaagaagcccaaggatgaggctttccggagccactacaagcctgaacagatgggtaaggatggca ggggttatgtcccagctaccatcaagatgaccgtggaaagggaccaaccacttcctaccccagagctccagatgcctacc atggtgccttcttatgaccttggaatggcccctgattcctccatgagcatgcagcttggcccagatatggtgccccaggt gtacccaccacactctcactccatccccccgtatcaaggcctctccccagaagaatcagtcaacgtgttgtcagccttcc aggagcctcacctgcagatgccccccagcctgggccagatgagcctgccctttgaccagcctcacccccagggcctgctg ccgtgccagcctcaggagcatgctgtgtccagccctgaccccctgctctgctcagatgtgaccatggtggaagacagctg cctgagccagccagtgacagcgtttcctcagggcacttggattggtgaagacatattccctcctctgctgcctcccactg aacaggacctcactaagcttctcctggaggggcaaggggagtcggggggagggtccttgggggcacagcccctcctgcag ccctcccactatgggcaatctgggatctcaatgtcccacatggacctaagggccaaccccagttggtgatcccagctgga gggagaacccaaagagacagctcttctactacccccacagacctgctctggacacttgctcatgccctgccaagcagcag atggggagggtgccctcctatccccacctactcctgggtcaggaggaaaagactaacaggagaatgcacagtgggtggag ccaatccactccttcctttctatcattcccctgcccacctccttccagcactgactggaagggaagttcaggctctgaga cacgccccaacatgcctgcacctgcagcgcgcacacgcacgcacacacacatacagagctctctgagggtgatggggctg agcagg (SEQ ID NO: 12174) gctttctcctagggactgtgaggggcgcttctgactttggacttgagcactgcctgggacctgtgctgagagagcgctag catgtctcagtggaatcaagtccaacagttagaaatcaagtttttggagcaggtggatcaattctatgatgacaactttc ccatggaaattcggcatctgttggcccaatggattgaaaatcaagactgggaggcagcttctaacaatgaaaccatggca acgattcttcttcaaaacttgttaatacaactggatgaacagttaggtcgtgtttccaaagagaaaaacctactcttgat acacaatctaaaaagaattaggaaggtccttcagggaaaatttcatggaaatccaatgcatgtagctgtggttatttcaa actgtttaagggaagagaggagaatattggctgcagccaacatgcctgtccaggggcctctagagaaatccttacaaagt tcttcagtttcagaaagacagaggaatgtggagcacaaagtggctgccattaaaaacagtgtgcagatgacagaacaaga taccaaatacttagaagatctgcaagacgaatttgactacaggtataaaacaattcagacaatggatcagagtgacaaga atagtgccatggtgaatcaggaagttttgacactgcaggaaatgcttaacagcctcgatttcaagagaaaggaggctctc agtaaaatgacccaaatcatccatgagacagacctgttaatgaacaccatgctcatagaagagctgcaagactggaagcg gcggcagcaaatcgcctgcatcgggggtccactccacaatgggctcgaccagcttcagaactgctttacactattggcag aaagtcttttccaactgagaaggcaattggagaaactagaggagcaatctaccaaaatgacatatgaaggtgatcccatt ccaatgcaaagaactcacatgctagaaagagtcaccttcttgatctacaaccttttcaagaactcatttgtggttgagcg acagccatgtatgccaacccaccctcagaggccgttggtacttaaaaccctaattcagttcactgtaaaactaaggctac taataaaattgccagaactaaactatcaggtaaaggttaaggcatcaattgacaagaatgtttcaactctaagcaaccga agatttgtactttgtggaactaatgtcaaagccatgtctattgaagaatcttccaatgggagtctctcagtagaatttcg acatttgcaaccaaaggaaatgaagtccagtgctggaggtaaaggaaatgagggctgtcacatggtgactgaagaacttc attccataacgtttgaaacacagatctgcctctatggcctgaccatagatttggagaccagctcattgcctgtggtgatg atttccaatgtcagtcagttacctaatgcttgggcatccatcatttggtacaacgtgtcaaccaacgattcccagaactt ggttttctttaataatcctccacctgccacattgagtcaactactggaggtgatgagctggcagttttcatcgtacgttg gtcgtggtcttaactcagatcaactccatatgctggcagagaagcttacagtccaatctagctacagtgatggtcacctc acctgggccaagttctgcaaggaacatttacctggtaaatcatttaccttttggacatggcttgaagcaatattggatct aattaagaaacacattcttcccctttggattgatgggtatgtcatgggctttgttagcaaagagaaggaacggctgttgc taaaggataaaatgcctggcacctttttattaagattcagtgaaagccatctcggaggaataactttcacctgggtggac cattctgaaagtggggaagtgagattccactctgtagaaccctacaataaaggccggttgtctgctctgccattcgctga catcctgcgagactacaaagttattatggctgaaaacattcctgaaaaccctctgaagtacctatatcctgacattccca aagacaaagccttcggtaaacactacagctctcagccttgcgaagtttcaagaccaacagaaaggggtgacaaaggttat gttccttctgtttttatccccatctcaacaatccgaagtgattcaacagagccacattctccatcagaccttcttcccat gtctccaagtgtgtatgcggtgttgagagaaaacctgagtcccacaacaattgaaactgcaatgaagtctccttattctg ctgaatgacaggataaactctgacgcaccaagaaaggaagcaaatgaaaaagtttaaagactgttctttgcccaataacc acattttatttcttcagctttgtaaataccaggttctaggaaatgtttgacatctgaagctctcttcacactcccgtggc actcctcaattgggagtgttgtgactgaaatgcttgaaaccaaagcttcagataaacttgcaagataagacaactttaag aaaccagtgttaataacaatattaacaggctttctcctagggactgtgaggggcgcttctgactttggacttgagcactg cctgggacctgtgctgagagagcgctagcatgtctcagtggaatcaagtccaacagttagaaatcaagtttttggagcag gtggatcaattctatgatgacaactttcccatggaaattcggcatctgttggcccaatggattgaaaatcaagactggga ggcagcttctaacaatgaaaccatggcaacgattcttcttcaaaacttgttaatacaactggatgaacagttaggtcgtg tttccaaagagaaaaacctactcttgatacacaatctaaaaagaattaggaaggtccttcagggaaaatttcatggaaat ccaatgcatgtagctgtggttatttcaaactgtttaagggaagagaggagaatattggctgcagccaacatgcctgtcca ggggcctctagagaaatccttacaaagttcttcagtttcagaaagacagaggaatgtggagcacaaagtggctgccatta aaaacagtgtgcagatgacagaacaagataccaaatacttagaagatctgcaagacgaatttgactacaggtataaaaca attcagacaatggatcagagtgacaagaatagtgccatggtgaatcaggaagttttgacactgcaggaaatgcttaacag cctcgatttcaagagaaaggaggctctcagtaaaatgacccaaatcatccatgagacagacctgttaatgaacaccatgc tcatagaagagctgcaagactggaagcggcggcagcaaatcgcctgcatcgggggtccactccacaatgggctcgaccag cttcagaactgctttacactattggcagaaagtcttttccaactgagaaggcaattggagaaactagaggagcaatctac caaaatgacatatgaaggtgatcccattccaatgcaaagaactcacatgctagaaagagtcaccttcttgatctacaacc ttttcaagaactcatttgtggttgagcgacagccatgtatgccaacccaccctcagaggccgttggtacttaaaacccta attcagttcactgtaaaactaaggctactaataaaattgccagaactaaactatcaggtaaaggttaaggcatcaattga caagaatgtttcaactctaagcaaccgaagatttgtactttgtggaactaatgtcaaagccatgtctattgaagaatctt ccaatgggagtctctcagtagaatttcgacatttgcaaccaaaggaaatgaagtccagtgctggaggtaaaggaaatgag ggctgtcacatggtgactgaagaacttcattccataacgtttgaaacacagatctgcctctatggcctgaccatagattt ggagaccagctcattgcctgtggtgatgatttccaatgtcagtcagttacctaatgcttgggcatcca catttggtaca acgtgtcaaccaacgattcccagaacttggttttctttaataatcctccacctgccacattgagtcaactactggaggtg atgagctggcagttttcatcgtacgttggtcgtggtcttaactcagatcaactccatatgctggcagagaagcttacagt ccaatctagctacagtgatggtcacctcacctgggccaagttctgcaaggaacatttacctggtaaatcatttacctttt ggacatggcttgaagcaatattggatctaattaagaaacacattcttcccctttggattgatgggtatgtcatgggcttt gttagcaaagagaaggaacggctgttgctaaaggataaaatgcctggcacctttttattaagattcagtgaaagccatct cggaggaataactttcacctgggtggaccattctgaaagtggggaagtgagattccactctgtagaaccctacaataaag gccggttgtctgctctgccattcgctgacatcctgcgagactacaaagttattatggctgaaaacattcctgaaaaccct ctgaagtacctatatcctgacattcccaaagacaaagccttcggtaaacactacagctctcagccttgcgaagtttcaag accaacagaaaggggtgacaaaggttatgttccttctgtttttatccccatctcaacaatccgaagtgattcaacagagc cacattctccatcagaccttcttcccatgtctccaagtgtgtatgcggtgttgagagaaaacctgagtcccacaacaatt gaaactgcaatgaagtctccttattctgctgaatgacaggataaactctgacgcaccaagaaaggaagcaaatgaaaaag tttaaagactgttctttgcccaataaccacattttatttcttcagctttgtaaataccaggttctaggaaatgtttgaca tctgaagctctcttcacactcccgtggcactcctcaattgggagtgttgtgactgaaatgcttgaaaccaaagcttcaga taaacttgcaagataagacaactttaagaaaccagtgttaataacaatattaacagatcttatttttctttttggtggtg gtggtggaaggggggaggtgctagcagggccagccttgaactcgctggacagagctacagacctatggggcctggaagtg cccgctgagaaagggagaagacagcagaggggttgccgaggcaacctccaagtcccagatcatgtctctgtggggtctgg tctccaagatgcccccagaaaaagtgcagcggctctatgtcgactttccccaacacctgcggcatcttctgggtgactgg ctggagagccagccctgggagttcctggtcggctccgacgccttctgctgcaacttggctagtgccctactttcagacac tgtccagcaccttcaggcctcggtgggagagcagggggaggggagcaccatcttgcaacacatcagcacccttgagagca tatatcagagggaccccctgaagctggtggccactttcagacaaatacttcaaggagagaaaaaagctgttatggaacag ttccgccacttgccaatgcctttccactggaagcaggaagaactcaagtttaagacaggcttgcggaggctgcagcaccg agtaggggagatccaccttctccgagaagccctgcagaagggggctgaggctggccaagtgtctctgcacagcttgatag aaactcctgctaatgggactgggccaagtgaggccctggccatgctactgcaggagaccactggagagctagaggcagcc aaagccctagtgctgaagaggatccagatttggaaacggcagcagcagctggcagggaatggcgcaccgtttgaggagag cctggccccactccaggagaggtgtgaaagcctggtggacatttattcccagctacagcaggaggtaggggcggctggtg gggagcttgagcccaagacccgggcatcgctgactggccggctggatgaagtcctgagaaccctcgtcaccagttgcttc ctggtggagaagcagcccccccaggtactgaagactcagaccaagttccaggctggagttcgattcctgttgggcttgag gttcctgggggccccagccaagcctccgctggtcagggccgacatggtgacagagaagcaggcgcgggagctgagtgtgc ctcagggtcctggggctggagcagaaagcactggagaaatcatcaacaacactgtgcccttggagaacagcattcctggg aactgctgctctgccctgttcaagaacctgcttctcaagaagatcaagcggtgtgagcggaagggcactgagtctgtcac agaggagaagtgcgctgtgctcttctctgccagcttcacacttggccccggcaaactccccatccagctccaggccctgt ctctgcccctggtggtcatcgtccatggcaaccaagacaacaatgccaaagccactatcctgtgggacaatgccttctct gagatggaccgcgtgccctttgtggtggctgagcgggtgccctgggagaagatgtgtgaaactctgaacctgaagttcat ggctgaggtggggaccaaccgggggctgctcccagagcacttcctcttcctggcccagaagatcttcaatgacaacagcc tcagtatggaggccttccagcaccgttctgtgtcctggtcgcagttcaacaaggagatcctgctgggccgtggcttcacc ttttggcagtggtttgatggtgtcctggacctcaccaaacgctgtctccggagctactggtctgaccggctgatcattgg cttcatcagcaaacagtacgttactagccttcttctcaatgagcccgacggaacctttctcctccgcttcagcgactcag agattgggggcatcaccattgcccatgtcatccggggccaggatggctctccacagatagagaacatccagccattctct gccaaagacctgtccattcgctcactgggggaccgaatccgggatcttgctcagctcaaaaatctctatcccaagaagcc caaggatgaggctttccggagccactacaagcctgaacagatgggtaaggatggcaggggttatgtcccagctaccatca agatgaccgtggaaagggaccaaccacttcctaccccagagctccagatgcctaccatggtgccttcttatgaccttgga atggcccctgattcctccatgagcatgcagcttggcccagatatggtgccccaggtgtacccaccacactctcactccat ccccccgtatcaaggcctctccccagaagaatcagtcaacgtgttgtcagccttccaggagcctcacctgcagatgcccc ccagcctgggccagatgagcctgccctttgaccagcctcacccccagggcctgctgccgtgccagcctcaggagcatgct gtgtccagccctgaccccctgctctgctcagatgtgaccatggtggaagacagctgcctgagccagccagtgacagcgtt tcctcagggcacttggattggtgaagacatattccctcctctgctgcctcccactgaacaggacctcactaagcttctcc tggaggggcaaggggagtcggggggagggtccttgggggcacagcccctcctgcagccctcccactatgggcaatctggg atctcaatgtcccacatggacctaagggccaaccccagttggtgatcccagctggagggagaacccaaagagacagctct tctactacccccacagacctgctctggacacttgctcatgccctgccaagcagcagatggggagggtgccctcctatccc cacctactcctgggtcaggaggaaaagactaacaggagaatgcacagtgggtggagccaatccactccttcctttctatc attcccctgcccacctccttccagcactgactggaagggaagttcaggctctgagacacgccccaacatgcctgcacctg cagcgcgcacacgcacgcacacacacatacagagctctctgagggtgatggggctgagcagg (SEQ ID NO: 12175) tttatttttaatttaatcacttaatttttaatttttaagatggagtctcactctgttgcccaggctgaagtgcaagggtg taatctcagctcactgcagcctctgcctcccggattccagtgattttcctgcttcagcttcccaggtagctgggattgca ggcacatgccactgtgcccagataattttttgtattttttagtagagacggggcttcaccatgttggccaggctggtctt gaactcctaacctcagatgatccgcacacctcggcctcccaaagtgctaggattacaggcatgagcctctgcgcctggcc tttacttcagtttcaaagagtgaaggtcaagacactgtttttttttatgttttgtttttaattttgttttaaattttttt tgtagagatgggatcttgctatgttgcccaggctggtctcgaactcctggcctccagcaatcctcctgcctcagcctccc agagtattgggattacaggtgtgagccattgtgcttgatcaagatgctgttatgggctgagttgtgttcctcaaaaattc tcttgaagtcctaatctcaagtacttcaggacgtgaccttattttgaaggacccccttatagggtctttacagaggtaat taagttaaaatgaggccattaggatggggcctaatgcaatatgactggtatccttgaaaaaaggggaaacttggagactg acttgcatacaaagagaacagtgtgtgaacgtgaaaatggccaaggagggaggcctggaatagagccttccttcacatcc ctgagaaggaatcaatcaatcctgctcaggttaaccttgatcttggacttctagcctccagcatcttgagagatttctgt tgtttaagtcatgcaatatgtagtactttgttacagcagccctagcaaactgatacactcaccaaatcgattttgtgact cactattgggttgtaaccagcagtacatagacataaagttattttttccttacgctttatcttgtgcaatcgtgtgtgtg tgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgacggagtcttgttctgtcaccaggctggagtgcagtggcttgat ctcggctcactataatcacagccttccagattcaagtgatttccctgcctcagcctcctgagtagctgggactacaggcg cgcaccaccacgcccgactaattttttgtatttttagtagagacggggtttcaccatgttggccaggatggtctcaatct cctgaccttgtgatctgcctgcctcagcctcccaaagtgctgggattacaggcgtgagcctctcttgtgcaatctttacc accactcaatgggatgtcaaggtccaggggagggtgatacagtcaccctcacagtcatgcaggtgcagatgtcattaatg aaggtctgacagaccctgcaattgtacaatctgaagatgagtatctccttaaatttcatactctaggcactttaccctag cctagactctgttgaagtaggtataactattattctcatttgagggattgacacctgattgtgaacctcctaaatggagt catacccaagccagatttgcctctaaattctgttttttccccttacatcacagtgttcccattggtatagtcagttacag agggagtaatatatactatttttctaccagtacttgctcctcgccttcctaccccctaaaaggagccaaagtcagagatc acatttactcttttccctcctcctctccaagtctttggggacttgtagctctgacacccttagatggtgaaacctggctt cacctactgtctgtggatgtctgcaggcagagtgggcactcaggagcacatacaaagcacgtgtgccgtgaacacgtatg tgcacacaccttgatcctagcatggcttgttggacaagccaatggacagagtccctgcctgccacctccacccctgctct cccttctcttccattcactgtcctgcagacacagcaaacacatacgcacatacaccctcaatatccttttggcagtaaca tgacccccaaatctggggacttctatgtaggatggagacccttctcctttcctcatacctggtttattatgaaccataaa aatagtgcctgacagttactgtgtgtcaggcattgttctaagccttcagatgttttactgcattttattctcacattatg ggttaagacttatttgctccattttacagatgacgagaatgaatcacagagtaaattgctcagggttgtgtggttagcag cattagcaggatttgaacccaagcagcctgtatccacagtccagtcttttaactgctatattttgctgtgttcaaaccct ctgctgcctggctgggtccacacacgtgcactcatgcacagacctgcggggtagcaagggatggaggaggaggagctggt tctggaaatcaattcaggcaccagggggcagcataggcctagctttggcccctcagcccagcccctgctatgggagggag gaggggagtagaaacttcctcccaccgcccctcagacaccacctcttccacacaccggggctctcaggtgtccgggagta aaggcctctctggatcccttggtctcctccagctcctcccccagcaaaaactgcagaaccctccactagttatgttgatg actcagaagttgagcaagactgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtggtgttgtgattg caatgggctctgtttgtgagcctgcctgcacgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtagtcttgtggtcaggga agttgtgcatgtgtgtgtttgtttcttggcgtgtctcagtgtttaccccagaaacatataggaacttggcagataggaac acagcagattcgtattcaaacttgccccttgtgaatctgcaggcagcagctccggcttgtgctggttcccaccacagtct caggaggggtgccctgtgaggagagagcaaagaccagcttcagtccaagggactcctagagtcttccagaattctgagct gagggttcccctcccccactccctcccgtcagtggtcacgagaccgacctctaaggcgttccctgccggaagggaggggg acctaggagttggctggcatcgagctccctggcggctttttagggtcctccactggagggagcgcagagtccagagggat ttacttttcctgaggccctggggagcccagtcccttgtgggtccaaaccccagcccttggcagagtttgagtttgggagc caggcagttaggggtggcaaatctctgtttgatattgggtgactttctggagaaaagctgatgcttttgagggggacaga gtaagtgggggtcagcctccccccaagcctggctccaaggcctggaccccagtcctgatcccccacgtgttcccccactc ggcacaggaggcacacatattcaccccactttcttcctcttcctcctccagcccactttctcttctctgtgtcgtcagag ctccagggagggacctgggtagaaggagaagccggaaacagcgggctggggcagccactgcttacactgaagagggagga cgggagaggagtgtgtgtgtgtgtgtgtgtgtgtgtgtgtatgtatgtgtgtgctttatcttatttttctttttggtggt ggtgttggaaggggggaggtgctagcagggccagccttgaactcgctggacagagctacagacctatggggcctggaagt gcccgctgagaaagggagaagacagcagaggggttgccgaggtgaggggttgcctccgaggtgggtgcgggggcctctat gagtgcatgggggtggattcgtggggggagctctcgggatcctcccctggctgggtggatggtccccaangagatggttt cagctantgttggtggctggtggcactgggttttancagtttcgaactcctggaggaactgggagggtccaggcctcant actcccctcccccatgggtcacgttttcacagcctcacccctgcacccccaagggcccatggaaagtcagggaaaggagg tgaaggagtgcccctctgccctgagtcgggggaagtggccgcccctccctggaaggttgatcgcagagggcagtggatcc ttgttaaacccctatcctgccctccactaaaggttcctgttcaagggtgtggctggggcgtgagcaagccccagatgtag acctcatggtggcccagacgagggggaatttccccctcaaaactgctccacgcttggctcgtgtagacgctgagatttcc cagcggcggcgccgaattaaccctcctcgtgctgaactggctccacctccccgccttgcccccaccgccacattcacgca ttgggcaactcagagaagatgttttaactttcgatcctgtggtccacaatgagaggactcgggcagataggggttgagat aagcgagtttaggccaccaagcgggcggacgaggatcccagaccttgcgcttcccttctgagtttgggaggtaacactgg ccccgcccctcacgccgtggctcctccctcccttccccttcaaggggctgaagacaaaaggtgcccctgtcctggtcaag ccaatcgacccagccttgttatgggttggggtggggaaaaatgagtcctcctgatggctggggaagaagaggggttggat atttctagccagggccatgccaggaggctggtcactctgcaaggggatgcagaggaaagcggagcccactcactccagag gacctttctcttcttgggctagagaaaggcctattggaggaacctgagcaggaggggtaaggattctgccttgaggagaa aagagctggggtaagtgggcactggaggaaagaggggcatgaaggtcttggagcagaaacgtccagagaagggacctctc cattttccatccctctgagaggcctgggagaggtgagaggctgaacgtgcaacaggaggacttggggttactgggtttgg ggagacctggggagttgtcatcccatcctctccctcatctctgggagagggatattatgagaaacgtgaactgagaggcc cctgggaaaccactggttacccagtcctccctgaacctggaaatggggatgcaaccccctcttctacttccctgtcccct cctctcctttctacctgttttcgtctctca ctttgccttctagccctccagcttcctctctcttctaggctctttcctc ctagcttactaaacccgccttttttccagtctcttccatcctcttccttagttctctctactttccttttccacctctcc tccttcaagtctcctcccaccttcccccacttcttaggatgatcagatttgcccctggaagggatcctaacaacacagtg cgatggttaatccccactcagattcaaagcctgctttccaaactcacttactgagtggccttgggcagagtagagaaact ccttaagcctcagtttcttcatctataaaatgggatattatatattttaaaaagtgtcgtgaggcctgaaggagataata cactgagtgtaatgcctcatacacagtaagtgcttaacaaatagtagctgttattactctcccatcctcttcatcatcta gccttgtggttttcatttttattttatttcatttatttatttatttattttgagcagagtctctctctgtcgcccaggct ggagtgcagtggctcgatctctgctcactgcaagctccgccccccaggttcacgccattctgtcacctcagcctccccag tagctgggagtacaggcgctcgccaccacgccctgctaattttgtttttgtatttttagtagagatggggtttcactgtg ttagccaggatggtcttgatctcctgacctcgtgatctgcccgcctcggcctcccaaagcgctgggattacaggcatgag ccactgcgcctggccgagccttgtggttttcaaattatctcatggagtcctagaattttgagaggtttgtctagggatgc ctttggcgtcaggaggtggggagagggaagtagaagcagtcgagtttcaggctttccatgcttgctttcaacagggcatc ttcggtttcgtaccttttatgtaattgagattccacagattaaaagctgacattgcctaccgctttaaaaagtttggaaa gttttccactcatctaacactcatattttatagatgagaagatcgaagcccacaaagggaaggctctttgcccacagaac cagagccaggtctagagctgcaactaaatcctctgccactctaagagagctctcgctctactgccctgtctccctttgcc tccccatccctctggctacagctcagctcttcccacccctgtgtctatcactgaaggagttacccccatctcaggcattg actcaggatgcccctggtttaaggtggtctggccatgagtggtggtggggacggtccctaggagggctatctatgggagg tcccctggctgccccaggagataggccaagtttctttgggcacccctcagagtggccttatttttttcctccaggcaacc tccaagtcccagatcatgtctctgtggggtctggtctccaagatgcccccagaaaaagtgcagcggctctatgtcgactt tccccaacacctgcggcatcttctgggtgactggctggagagccagccctggtgagtcctggctgctccctgctggtccc ccaagtcttccctaactcatcttccttctccttagatttttctcccctcacccatggattcagaacttgagacctgttat tccatgtgtagtgacctagatttagcagggagtctgtgccccatcaagaccaggctatgaatgttgacagatggagaccc ccatctcttaggaggctgagccgaagaggaggggggtttgggctgggacaaaggcacttctcataacagctagaagactg ggaaacaaggcgcatgggtgaaagctacagagggcctagatggagaataaggagcgagaaaggaatgctgacttttggct gtggggtaaaggtcaggaaactgaagaagcctggcctgaagtacctctcctgatcttcctgcaagggagttcctggtcgg ctccgacgccttctgctgcaacttggctagtgccctactttcagacactgtccagcaccttcaggcctcggtgggagagc agggggaggggagcaccatcttgcaacacatcagcacccttgaggtggggcaggaggggaggggacaaggctgggtgggg ctgaggttgaactgggttgagcattgggccctggaagaaaattggttggatgctggaagcaaattggtgttcctgtggtt aactgctagctagcaggcaaattagattttaaaagcatgcaaatgcacaaaaacttctggagtctacagttgtgcttcct tatagtatatgtgtgaatgcaggcctggggattggagggattgaaggacatgggtaagagcaaagctcactgtttaccac cctcatttctgtagagcatatatcagagggaccccctgaagctggtggccactttcagacaaatacttcaaggagagaaa aaagctgttatggaacaggtattgtgatattccacctcccaccccaactcaatcccctgagactttggcctgagccatga caaactagaaagaatttgatcctcagaaaaggctcagtgttctaggcccaggaatgaccaaaggaggttcctagggtcag agtgaaccccaagtcaagctcagggaatctttctatgagggactgaaggtaagaggccggggagaacagagcaagggata aggagctgattctgctaggagcaaggtcttatctccacgatattccaaaaggtcaggaagaactgccaaaggggagaggg gaacaagaaaacgctatatgcagagcagagagtggaggccaggtatagagggatgagcagagtgtttgagttcttggcat ctgtccttcctgtgtagttccgccacttgccaatgcctttccactggaagcaggaagaactcaagtttaagacaggcttg cggaggctgcagcaccgagtaggggagatccaccttctccgacaagccctgcagaagggggctgaggctggccaaggtgg gggccagggtggttctggggagtgtgtaagagtggttgcctcttggatctcaaccttatctgaacctctaatctgtctgc acccttgatttctgcccccaaccctcagtgtctctgcacagcttgatagaaactcctgctaatgggactgggccaagtga ggtgagtaatgggctgacaggtggagaccttggtcaaagtgcagctggagggatggaagctagacctcagaaagacacag gctgaagtagggcaagggaatgccagaggagtgagaaaaagaccgtatcccaggagctgggtgtggaggcagcgtgaggc cctggctcaggcccctctctgcccataggccctggccatgctactgcaggagaccactggagagctagaggcagccaaag ccctagtgctgaagaggatccagatttggaaacggcagcagcagctggcagggaatggcgcaccgtttgaggagagcctg gccccactccaggagaggttgggctagggctgatggggaagagggggcaagctgggggtgggcagctgaccctgctgaag gccctacaggtgagagaaagaagccaggcgggagggccttggcagtggaccaagatgcataaaagccagttccagcgggg ctgtgcacactgtcgttcaggtcgcatcctgtacaagtgggcctagtggaggggcacaagcggggactcatccaacccag gcttctctcctcaagccccatgcctagaggaataggagggcttttccatttggtttattgggtgggaacacttcccaatt tgccacaaagcactgtaagtggtggcagttgttcttgggtgcaagaaccgtcggggagaggcagctgggtttccacaggg ggtgtaggcaactgataatgaacctcccacccacaccctaggccaacagatcacagaaccccttcagcccaggtgccttg cagccacacccactacccaccccacttctccacacatgatagcctttctccctgggtataggggaagggggtctgggccg gagcaagcagccttaatcctgtgccccctgaccactgtcctggccccaggtgtgaaagcctggtggacatttattcccag ctacagcaggaggtaggggcggctggtggggagcttgagcccaagacccgggcatcgctgactggccggctggatgaagt cctgagaaccctcgtcaccaggtattccccgggagctcccagtctggcctagaacagacctcgggaagaaaagaaggggg ctagagctgtggggagggcaccagcagggacctagcccccaactccccttgtgtcctcctcactcccagttgcttcctgg tggagaagcagcccccccaggtactgaagactcagaccaagttccaggctggagttcgattcctgttgggcttgaggttc ctgggggccccagccaagcctccgctggtcagggccgacatggtgacagagaagcaggcgcgggagctgagtgtgcctca gggtcctggggctggagcgtaagctgggattggacctggggttggagaagggctgttagggtgatggaggcagcctggag ggctggcactgaaaagagcaagggatggggagggagggccatgggatgtggagaccctgaatggtcaaggcagaggaaag ggagggacccatttagggctggaatggggtgggggcatcatgatttggccaagatggggactcctcccttaagaacccaa acagagacatggagatttagggctggtgacagtgggtagtctacactcacccatgcactcgccacacctgacgacagtga gatgagctcgttcacactctgacctcccctgggcagagaaagcactggagaaa catcaacaacactgtgcccttggaga acagcattcctgggaactgctgctctgccctgttcaagaacctggtgaggggctttggggtgcagtgaggggggcaccac taggagactgtgggactctccttggagaggatgtcaggaagcccaggaggagcggtctctgtcctcatgacctcgccctt gctctccctcaccccacccacagcttctcaagaagatcaagcggtgtgagcggaagggcactgagtctgtcacagaggag aagtgcgctgtgctcttctctgccagcttcacacttggccccggcaaactccccatccagctccaggtgaaccgtggccc agccctgccccaatctgggaccccgagtcctcctccaatgccacgcacaagggccctggaccctcacctcttgtgactgc cccataccccatgtgtctgggattcatgcacactggggcccgggtgagtgggggtgagcaagagcatggagtgcacaggg cagggaatggtagtggatagcagcaaacacttcggaagcacttcctatagaccaggggcactctattaaatgatacatac tgcacatgcgtgccagcacacacacgtctggttttcacaataacattatgaggtaggcagtattatcagcctcattttat agcatgaggacattgagacagagagtttaagtagtttgtcccagtcacccagctaagtgttggagctggtatctgaaacc tggaagtctggttccatagcgattatagtaaccacttctctacggtgaggccctgattgagcttcaaaacgcatttaata acatgg (SEQ ID NO: 12176) ggaaagaaagaaagaaaagaaaccctgtcctcaccctacttcaggccctgtctctgcccctggtggtcatcgtccatggc aaccaagacaacaatgccaaagccactatcctgtgggacaatgccttctctgagatggtgaggaaagtccttggtagttg gagggaacagggtgcagggtgggttctaacatgggcagtggtgcaggcctgctgatggggtggtgggcatgtcggatggg tgtgaccttaacacttcttcatgggcctgctttcgtgcttctgacctcttttcaccccagtcttaacaactatcaggcca cagcactgtaacctagaaaaaacagcatgtttgtgagcgatatcaggggctgtggaggggtaggccacaggcatgtggga cggatgaaggccggcccgaggaataacaagacggtagcctgcagtgctctcttcttcccccttctccccaggaccgcgtg ccctttgtggtggctgagcgggtgccctgggagaagatgtgtgaaactctgaacctgaagttcatggctgaggtggggac caaccgggggctgctcccagagcacttcctcttcctggcccagaagatcttcaatgacaacagcctcagtatggaggcct tccagcaccgttctgtgtcctggtcgcagttcaacaaggttcagttctcc (SEQ ID NO: 12177) gcggccgcgagctctaatacgactcactatagggcgtcgactcgatcataccactgcactcaagcctgggtgacagagca agactctgtctcaaaaaaaaaaaaaaaaaaaggccaggcatggtggttcatgcctgtaatcccagcactttgggaggccg agacggatagatcacctgaggtcaggagttcgagaccagcctggccaacatggcaaaaccccgtctctactaaaaacaaa aaaatagccaggatggtcgtttgcgtctgtaatcccagctactcggctgaggcaggaggtgaacccaggaggtaaaggct gcaggggaagatgaaaccattgcactccagcctgggcaagactctgtatcaaaaaaaaaaaaaaaaaggctaggtgtggt ggctcacacctgtaatcccagcactttgggaggctgaggcgggcggatcacaaggtcaagaaatcgagaccatcctgacc aacatggtgaaaccccgtctctactaaaaatacaaaaattacctgggcatggtggcgcatgcctgtattcccaactactc gggaggctgaggcatgaaaatcacttgaacctgggaggcagaggttgcaggcgagccaagattgtgccactgcactccag cctgccaacaaaaatgagattctgtc (SEQ ID NO:12178) ggttaccttccctttgggcgtcaacttctgccacacctccttagggagagggtgtagcatagtagttaagaggggtccag ggccagaatgcctgggtttaaatcctagctctgcctcttaccagctatgtagacctgggcaagtcattcgacgtttttgg acttccatttcttcatctgtaagatggaattattataatccctacttccatagcctggtaaagagcaaataaatatatgg aaaggcttgaaatagtggctggcacgtgtaagcattaggattggtcgttgtcattgatggagtctcaggttcggtctgat cctcagcccctgtgattctgtcgtgagggcactcacagctcactgcctgccctaaacaggctccagctctggccctccct cggctcacacctttccccctctccccctaggagatcctgctgggccgtggcttcaccttttggcagtggtttgatggtgt cctggacctcaccaaacgctgtctccggagctactggtctgaccggtgagtccccaccctgggtagtttgagcagccata caccagtcacctccatactcactgcccatgccccatcctctccttcatcccggccaggctgatcattggcttcatcagca aacagtacgttactagccttcttctcaatgagcccgacggaacctttctcctccgcttcagcgactcagagattgggggc atcaccattgcccatgtcatccggggccaggatggtgaggccaccccagccagtcctctgtctctgtgcctgtgccctct ggggtttcttctgggaatgaaatgtcctgaccttcctgatgccgatcctgatcttcaggaagttcttccagcttctcttc ttccttctgtggtctaaatgttcaccttctcactgtgagctctgtgggaacggagactagtgggtctctctccctcagga gccccaccctaggtcctctctcccttgccttggtggagtgagaacaggtcttatggtaggggttggggaaggggaagaaa tccggacagagggatctcagggtctccttcctaccataggctctccacagatagagaacatccagccattctctgccaaa gacctgtccattcgctcactgggggaccgaatccgggatcttgctcagctcaaaaatctctatcccaagaagcccaagga tgaggctttccggagccactacaagcgtgagctggaactggcagctctgattccttcctgtcacccacttcctgccatgc tccccgctgccatcctctccccagcccgtgagttatcctgaggtcactccgaatttccatagctgtgcttttcttacttc ccggatgatccatgcccaccttttccacctcccttcctccctaacccgagagcaatccatggcagtcttttccatctcac aacagctgaacagctgaacagatgggtaaggatggcaggggttatgtcccagctaccatcaagatgaccgtggaaaggtg agtgtggtggtatggacagtgggtaggtcaggggcttagtgcttatctgcaggaaggaggggtggcatcaacccttggtc agtcacatgtacctccttccctcctccagggaccaaccacttcctaccccagagctccagatgcctaccatggtgccttc ttatgaccttggaatggcccctgattcctccatgagcatgcagcttggcccagatatggtgtaaggagctggaaagacag gaatgggagtggtctgtgcagatgggctaatcttagcatgggcagctgggagagctggcactgggggctgaacagggaat cttcctttccatgagagggacacctgttcaaaagcagggtgtggtggtgtccaggagaagggctggcatcagggggtctg ttttctttccccaggccccaggtgtacccaccacactctcactccatccccccgtatcaaggcctctccccagaagaatc agtcaacgtgttgtcagccttccaggagtaagtgaaaaacctcatggggataccatcccactctaagggggtgggcattt gaattgttagaagaggctcttctgtgagaaaggagcagcaaatgctaacagcctgtcttcttctcttctgtccactctaa tgagggggtagtagttaagatctggactgcctaggtttgaattctagctccaccacttactggtttggggcaaattactt agcctttggtgccttatctgcacaatgggggataataatgctaataataataacctacctcactgcattattgtggagat taaatgagttcataacacttaaaaagctcgagcatagtgcatggctcatagcaaaagctgtgtaagtccagtcgtggatc acttaatgaaggagcattttctgtctttggcagtttcataattatgcggaataccattgagtataattacacaaacctag atggtatagactactatacactgaggctatattgtgtagcctattgatcctagctttaaacccgagcagcatgatactgt tctgaatagtataaggaaatagtaacataatggtaaatatttgtgtgataggaattttcagcttgattataatttttttt ttttgagacagggtctcactcactggagtgcagtggtgcgatcttagctcccctgcaacctccgcctcttgggctcgagc aatcctcctgctgtagtgcaccacgacactcggctaattcttttttaagatttttctgcagacaaggtctcacttactgc ccaagctggtctcaaactcctgggcttaagtgatcctcccacctcggcctcccaaagcgttaggattacaggcgtgagtc actctgcctggccttgattataatcttatgggaccactgtggtctgtagttgacagaaatgtcgttaatgtggtgcatga ctgttattattattttctgtcctgcccctgagagccactgtcacttctctgctgtattggtttttgtttactcatctgtt ttggccttgaaatggcctagacatttttcttcccgaagtatgacactcgggtgcttattaacttagtcaagacacaacat ctcccttcccagaaagtgaggcgggagtgaggacttggggacttaagaactaccaaagttcagagtccaaaggaaacatt agaaattgggtaatccacccccataacacgcacattttacagatgagaagactgagctcagagcatagaaatagcttgcc caggccatgactaagtcaggataaggagctggagcttgtttcctcactcagtggtcctgactttgcaccactctgcattt gcctagcctgccttcctctaactgtgctctccctacttccaggcctcacctgcagatgccccccagcctgggccagatga acctgccctttgaccagcctcacccccaggtgaatgacaaaagcccctcctgacccatgtgcctcttctttcctgggcct tgcccgctctccttatttccattgctggttcctggcagggcctgctgccgtgccagcctcaggagcatgctgtgtccagc cctgaccccctgctctgctcagatgtgaccatggtggaagacagctgcctgagccagccagtgacagcgtttcctcaggg cacttggtgagtggcagcttgggagtggaggctgggtggcatctaggggagtgggcgccatgcctactccactgcttctc ccatctccttgcaggattggtgaagacatattccctcctctgctgcctcccactgaacaggacctcactaagcttctcct ggaggggcaaggggagtcggggggagggtccttgggggcacagcccctcctgcagccctcccactatgggcaatctggga tctcaatgtcccacatggacctaagggccaaccccagttggtgatcccagctggagggagaacccaaagagacagctctt ctactacccccacagacctgctctggacacttgctcatgccctgccaagcagcagatggggagggtgccctcctatcccc acctactcctgggtcaggaggaaaagactaacaggagaatgcacagtgggtggagccaatccactccttcctttctatca ttcccctgcccacctccttccagcactgactggaagggaagttcaggctctgagacacgccccaacatgcctgcacctgc agcgcgcacacgcacgcacacacacatacagagctctctgagggtgatggggctgagcaggaggggggctgggtaagagc acaggttagggcatggaaggcttctccgcccattctgacccagggcctaggacggataggcaggaacatacagacacatt tacactagaggccagggatagaggatattgggtctcagccctaggggaatgggaagcagctgaagggaccctgggtggga gcataggaggagtctggacatgtggttactagtacaggttttgccctgattaaaaaatctcccaaagccccaaattcctg ttagccaggtggaggcttctgatacgtgtatgagactatgcaaaagtacaagggctgagattcttcgtgtatagctgtgt gaacgtgtatgtacctaggatatgttaaatatatagctggcaccttagttgcatgaccacatagaacatgtgtctatctg cttttgcctacgtgacaacacaaatttgggagggtgagacactgcacagaagacagcagcaagtgtgctggcctctctga catatgctaacccccaaat ctctgaatttggagtctgactgtgcccaagtgggtccaagtggctgtgacatctacgtat ggctccacacctccaatgctgcctgggagccagggtgagagtctgggtccaggcctggccatgtggccctccagtgtatg agagggccctgcctgctgcatcttttctgttgccccatccaccgccagcttcccttcactcccctatcccattctccctc tcaaggcaggggtcatagatcctaagccataaaataaattttattccaaaataacaaaataaataatctactgtacacaa tctgaaaagaaagacgctctaactgctcagataggtgctgcggtccagcccccagctggaggagaccctgagtccaaccc aggcctcccgagggggccagtgaagggatcccacacccaccgcccctatgtagggcagggaagaaattgcaaaggacttg ggggatagatgggaatgggagggcaaactgcagcacttgttaaattaattaaagaaacaaaccagaagcacaaaaacggg gaaggagaagggagaaggagcaggtccagtgttccaggccccaattctgggggcaaatgtgcca (SEQ ID NO: 12179) gcagcacctatctgagcagttagagcgtctttcttttcagattgtgtacagtagattatttattttgttattttggaata aaatttattttatggcttaggatctatgacccctgccttgagagggagaatgggataggggagtgaagggaagctggcgg tggatggggcaacagaaaagatgcagcaggcagggccctctcatacactggagggccacatggccaggcctggacccaga ctctcaccctggctcccaggcagcattggaggtgtggagccatacgtagatgtcacagccacttggacccacttgggcac agtcagactccaaattcagagtatttgggggttagcatatgtcagagaggccagcacacttgctgctgtcttctgtgcag - tgtctcaccctcccaaatttgtgttgtcacgtaggcaaaagcagatagacacatgttctatgtggtcatgcaactaaggt gccagctatacatttaaca atcctaggtacatacacgttcacacagctatacacgaagaatctcagcccttgtactttt gcatagtctcatacacgtatcagaagcctccacctggctaacaggaatttggggctttgggagattttttaatcagggca aaacctgtactagtaaccacatgtccagacccctcctatgctcccacccagggtcccttgagctgcttcccattccccta gggctgagacccaatatcctctatccctggcctctagtgtaaatgtgtctgtatgttcctgcctatccgtcctaggccct gggtcagaatgggcggagaagccttccatgccctaacctgtgctcttacccagcccccctcctgctcagccccatcaccc tcagagagctctgtatgtgtgtgtgcgtgcgtgtgcgcgctgcaggtgcaggcatgttggggtgtgtctcagagcctgaa cttcccttccagtcagtactggaaggaggtgggcaggggaatgatagaaaggaaggagtggattggctccacccactgtg cattctcctgttagtcttttcctcctgacccaggagtaggtggggataggagggcaccctccccatctgctgcttggcag ggcatgagcaagtgtccagagcaggtctgtgggggtagtagaagagctgtctctttgggttctccctccagctgggatca ccaactggggttggcccttaggtccatgtgggacattgagatcccagattgcccatagtgggagggctgcaggaggggct gtgcccccaaggaccctccccccgactccccttgcccctccaggagaagcttagtgaggtcctgttcagtgggaggcagc agaggagggaatatgtcttcaccaatcctgcaaggagatgggagaagcagtggagtaggcatggcgcccactcccctaga tgccacccagcctccactcccaagctgccactcac (SEQ ID NO:12180) tttatttttaatttaatcacttaatttttaatttttaagatggagtctcactctgttgcccaggctgaagtgcaagggtg taatctcagctcactgcagcctctgcctcccggattccagtgattttcctgcttcagcttcccaggtagctgggattgca ggcacatgccactgtgcccagataattttttgtattttttagtagagacggggcttcaccatgttggccaggctggtctt gaactcctaacctcagatgatccgcacacctcggcctcccaaagtgctaggattacaggcatgagcctctgcgcctggcc tttacttcagtttcaaagagtgaaggtcaagacactgtttttttttatgttttgtttttaattttgttttaaattttttt tgtagagatgggatcttgctatgttgcccaggctggtctcgaactcctggcctccagcaatcctcctgcctcagcctccc agagtattgggattacaggtgtgagccattgtgcttgatcaagatgctgttatgggctgagttgtgttcctcaaaaattc tcttgaagtcctaatctcaagtacttcaggacgtgaccttattttgaaggacccccttatagggtctttacagaggtaat taagttaaaatgaggccattaggatggggcctaatgcaatatgactggtatccttgaaaaaaggggaaacttggagactg acttgcatacaaagagaacagtgtgtgaacgtgaaaatggccaaggagggaggcctggaatagagccttccttcacatcc ctgagaaggaatcaatcaatcctgctcaggttaaccttgatcttggacttctagcctccagcatcttgagagatttctgt tgtttaagtcatgcaatatgtagtactttgttacagcagccctagcaaactgatacactcaccaaatcgattttgtgact cactattgggttgtaaccagcagtacatagacataaagttattttttccttacgctttatcttgtgcaatcgtgtgtgtg tgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgacggagtcttgttctgtcaccaggctggagtgcagtggcttgat ctcggctcactataatcacagccttccagattcaagtgatttccctgcctcagcctcctgagtagctgggactacaggcg cgcaccaccacgcccgactaattttttgtatttttagtagagacggggtttcaccatgttggccaggatggtctcaatct cctgaccttgtgatctgcctgcctcagcctcccaaagtgctgggattacaggcgtgagcctctcttgtgcaatctttacc accactcaatgggatgtcaaggtccaggggagggtgatacagtcaccctcacagtcatgcaggtgcagatgtcattaatg aaggtctgacagaccctgcaattgtacaatctgaagatgagtatctccttaaatttcatactctaggcactttaccctag cctagactctgttgaagtaggtataactattattctcatttgagggattgacacctgattgtgaacctcctaaatggagt catacccaagccagatttgcctctaaattctgttttttccccttacatcacagtgttcccattggtatagtcagttacag agggagtaatatatactatttttctaccagtacttgctcctcgccttcctaccccctaaaaggagccaaagtcagagatc acatttactcttttccctcctcctctccaagtctttggggacttgtagctctgacacccttagatggtgaaacctggctt cacctactgtctgtggatgtctgcaggcagagtgggcactcaggagcacatacaaagcacgtgtgccgtgaacacgtatg tgcacacaccttgatcctagcatggcttgttggacaagccaatggacagagtccctgcctgccacctccacccctgctct cccttctcttccattcactgtcctgcagacacagcaaacacatacgcacatacaccctcaatatccttttggcagtaaca tgacccccaaatctggggacttctatgtaggatggagacccttctcctttcctcatacctggtttattatgaaccataaa aatagtgcctgacagttactgtgtgtcaggcattgttctaagccttcagatgttttactgcattttattctcacattatg ggttaagacttatttgctccattttacagatgacgagaatgaatcacagagtaaattgctcagggttgtgtggttagcag cattagcaggatttgaacccaagcagcctgtatccacagtccagtcttttaactgctatattttgctgtgttcaaaccct ctgctgcctggctgggtccacacacgtgcactcatgcacagacctgcggggtagcaagggatggaggaggaggagctggt tctggaaatcaattcaggcaccagggggcagcataggcctagctttggcccctcagcccagcccctgctatgggagggag gaggggagtagaaacttcctcccaccgcccctcagacaccacctcttccacacaccggggctctcaggtgtccgggagta aaggcctctctggatcccttggtctcctccagctcctcccccagcaaaaactgcagaaccctccactagttatgttgatg actcagaagttgagcaagactgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtggtgttgtgattg caatgggctctgtttgtgagcctgcctgcacgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtagtcttgtggtcaggga agttgtgcatgtgtgtgtttgtttcttggcgtgtctcagtgtttaccccagaaacatataggaacttggcagataggaac acagcagattcgtattcaaacttgccccttgtgaatctgcaggcagcagctccggcttgtgctggttcccaccacagtct caggaggggtgccctgtgaggagagagcaaagaccagcttcagtccaagggactcctagagtcttccagaattctgagct gagggttcccctcccccactccctcccgtcagtggtcacgagaccgacctctaaggcgttccctgccggaagggaggggg acctaggagttggctggcatcgagctccctggcggctttttagggtcctccactggagggagcgcagagtccagagggat ttacttttcctgaggccctggggagcccagtcccttgtgggtccaaaccccagcccttggcagagtttgagtttgggagc caggcagttaggggtggcaaatctctgtttgatattgggtgactttctggagaaaagctgatgcttttgagggggacaga gtaagtgggggtcagcctccccccaagcctggctccaaggcctggaccccagtcctgatcccccacgtgttcccccactc ggcacaggaggcacacatattcaccccactttcttcctcttcctcctccagcccactttctcttctctgtgtcgtcagag ctccagggagggacctgggtagaaggagaagccggaaacagcgggctggggcagccactgcttacactgaagagggagga cgggagaggagtgtgtgtgtgtgtgtgtgtgtgtgtgtgtatgtatgtgtgtgctttatcttatttttctttttggtggt ggtgttggaaggggggaggtgctagcagggccagccttgaactcgctggacagagctacagacctatggggcctggaagt gcccgctgagaaagggagaagacagcagaggggttgccgaggtgaggggttgcctccgaggtgggtgcgggggcctctat gagtgcatgggggtggattcgtggggggagctctcgggatcctcccctggctgggtggatggtccccaangagatggttt cagctantgttggtggctggtggcactgggttttancagtttcgaactcctggaggaactgggagggtccaggcctcant actcccctcccccatgggtcacgttttcacagcctcacccctgcacccccaagggcccatggaaagtcagggaaaggagg tgaaggagtgcccctctgccctgagtcgggggaagtggccgcccctccctggaaggttgatcgcagagggcagtggatcc ttgttaaacccctatcctgccctccactaaaggttcctgttcaagggtgtggctggggcgtgagcaagccccagatgtag acctcatggtggcccagacgagggggaatttccccctcaaaactgctccacgcttggctcgtgtagacgctgagatttcc cagcggcggcgccgaattaaccctcctcgtgctgaactggctccacctccccgccttgcccccaccgccacattcacgca ttgggcaactcagagaagatgttttaactttcgatcctgtggtccacaatgagaggactcgggcagataggggttgagat aagcgagtttaggccaccaagcgggcggacgaggatcccagaccttgcgcttcccttctgagtttgggaggtaacactgg ccccgcccctcacgccgtggctcctccctcccttccccttcaaggggctgaagacaaaaggtgcccctgtcctggtcaag ccaatcgacccagccttgttatgggttggggtggggaaaaatgagtcctcctgatggctggggaagaagaggggttggat atttctagccagggccatgccaggaggctggtcactctgcaaggggatgcagaggaaagcggagcccactcactccagag gacctttctcttcttgggctagagaaaggcctattggaggaacctgagcaggaggggtaaggattctgccttgaggagaa aagagctggggtaagtgggcactggaggaaagaggggcatgaaggtcttggagcagaaacgtccagagaagggacctctc cattttccatccctctgagaggcctgggagaggtgagaggctgaacgtgcaacaggaggacttggggttactgggtttgg ggagacctggggagttgtcatcccatcctctccctcatctctgggagagggatattatgagaaacgtgaactgagaggcc cctgggaaaccactggttacccagtcctccctgaacctggaaatggggatgcaaccccctcttctacttccctgtcccct cctctcctttctacctgttttcgtctctcatctttgccttctagccctccagcttcctctctcttctaggctctttcctc ctagcttactaaacccgccttttttccagtctcttccatcctcttccttagttctctctactttccttttccacctctcc tccttcaagtctcctcccaccttcccccacttcttaggatgatcagatttgcccctggaagggatcctaacaacacagtg cgatggttaatccccactcagattcaaagcctgctttccaaactcacttactgagtggccttgggcagagtagagaaact ccttaagcctcagtttcttcatctataaaatgggatattatatattttaaaaagtgtcgtgaggcctgaaggagataata cactgagtgtaatgcctcatacacagtaagtgcttaacaaatagtagctgttattactctcccatcctcttcatcatcta gccttgtggttttcatttttattttatttcatttatttatttatttattttgagcagagtctctctctgtcgcccaggct ggagtgcagtggctcgatctctgctcactgcaagctccgccccccaggttcacgccattctgtcacctcagcctccccag tagctgggagtacaggcgctcgccaccacgccctgctaattttgtttttgtatttttagtagagatggggtttcactgtg ttagccaggatggtcttgatctcctgacctcgtgatctgcccgcctcggcctcccaaagcgctgggattacaggcatgag ccactgcgcctggccgagccttgtggttttcaaattatctcatggagtcctagaattttgagaggtttgtctagggatgc ctttggcgtcaggaggtggggagagggaagtagaagcagtcgagtttcaggctttccatgcttgctttcaacagggcatc ttcggtttcgtaccttttatgtaattgagattccacagattaaaagctgacattgcctaccgctttaaaaagtttggaaa gttttccactcatctaacactcatattttatagatgagaagatcgaagcccacaaagggaaggctctttgcccacagaac cagagccaggtctagagctgcaactaaatcctctgccactctaagagagctctcgctctactgccctgtctccctttgcc tccccatccctctggctacagctcagctcttcccacccctgtgtctatcactgaaggagttacccccatctcaggcattg actcaggatgcccctggtttaaggtggtctggccatgagtggtggtggggacggtccctaggagggctatctatgggagg tcccctggctgccccaggagataggccaagtttctttgggcacccctcagagtggccttatttttttcctccaggcaacc tccaagtcccagatcatgtctctgtggggtctggtctccaagatgcccccagaaaaagtgcagcggctctatgtcgactt tccccaacacctgcggcatcttctgggtgactggctggagagccagccctggtgagtcctggctgctccctgctggtccc ccaagtcttccctaactcatcttccttctccttagatttttctcccctcacccatggattcagaacttgagacctgttat tccatgtgtagtgacctagatttagcagggagtctgtgccccatcaagaccaggctatgaatgttgacagatggagaccc ccatctcttaggaggctgagccgaagaggaggggggtttgggctgggacaaaggcacttctcataacagctagaagactg ggaaacaaggcgcatgggtgaaagctacagagggcctagatggagaataaggagcgagaaaggaatgctgacttttggct gtggggtaaaggtcaggaaactgaagaagcctggcctgaagtacctctcctgatcttcctgcaagggagttcctggtcgg ctccgacgccttctgctgcaacttggctagtgccctactttcagacactgtccagcaccttcaggcctcggtgggagagc agggggaggggagcaccatcttgcaacacatcagcacccttgaggtggggcaggaggggaggggacaaggctgggtgggg ctgaggttgaactgggttgagcattgggccctggaagaaaattggttggatgctggaagcaaattggtgttcctgtggtt aactgctagctagcaggcaaattagattttaaaagcatgcaaatgcacaaaaacttctggagtctacagttgtgcttcct tatagtatatgtgtgaatgcaggcctggggattggagggattgaaggacatgggtaagagcaaagctcactgtttaccac cctcatttctgtagagcatatatcagagggaccccctgaagctggtggccactttcagacaaatacttcaaggagagaaa aaagctgttatggaacaggtattgtgatattccacctcccaccccaactcaatcccctgagactttggcctgagccatga caaactagaaagaatttgatcctcagaaaaggctcagtgttctaggcccaggaatgaccaaaggaggttcctagggtcag agtgaaccccaagtcaagctcagggaatctttctatgagggactgaaggtaagaggccggggagaacagagcaagggata aggagctgattctgctaggagcaaggtcttatctccacgatattccaaaaggtcaggaagaactgccaaaggggagaggg gaacaagaaaacgctatatgcagagcagagagtggaggccaggtatagagggatgagcagagtgtttgagttcttggcat ctgtccttcctgtgtagttccgccacttgccaatgcctttccactggaagcaggaagaactcaagtttaagacaggcttg cggaggctgcagcaccgagtaggggagatccaccttctccgacaagccctgcagaagggggctgaggctggccaaggtgg gggccagggtggttctggggagtgtgtaagagtggttgcctcttggatctcaaccttatctgaacctctaatctgtctgc acccttgatttctgcccccaaccctcagtgtctctgcacagcttgatagaaactcctgctaatgggactgggccaagtga ggtgagtaatgggctgacaggtggagaccttggtcaaagtgcagctggagggatggaagctagacctcagaaagacacag gctgaagtagggcaagggaatgccagaggagtgagaaaaagaccgtatcccaggagctgggtgtggaggcagcgtgaggc cctggctcaggcccctctctgcccataggccctggccatgctactgcaggagaccactggagagctagaggcagccaaag ccctagtgctgaagaggatccagatttggaaacggcagcagcagctggcagggaatggcgcaccgtttgaggagagcctg gccccactccaggagaggttgggctagggctgatggggaagagggggcaagctgggggtgggcagctgaccctgctgaag gccctacaggtgagagaaagaagccaggcgggagggccttggcagtggaccaagatgcataaaagccagttccagcgggg ctgtgcacactgtcgttcaggtcgcatcctgtacaagtgggcctagtggaggggcacaagcggggactcatccaacccag gcttctctcctcaagccccatgcctagaggaataggagggcttttccatttggtttattgggtgggaacacttcccaatt tgccacaaagcactgtaagtggtggcagttgttcttgggtgcaagaaccgtcggggagaggcagctgggtttccacaggg ggtgtaggcaactgataatgaacctcccacccacaccctaggccaacagatcacagaaccccttcagcccaggtgccttg cagccacacccactacccaccccacttctccacacatgatagcctttctccctgggtataggggaagggggtctgggccg gagcaagcagccttaatcctgtgccccctgaccactgtcctggccccaggtgtgaaagcctggtggacatttattcccag ctacagcaggaggtaggggcggctggtggggagcttgagcccaagacccgggcatcgctgactggccggctggatgaagt cctgagaaccctcgtcaccaggtattccccgggagctcccagtctggcctagaacagacctcgggaagaaaagaaggggg ctagagctgtggggagggcaccagcagggacctagcccccaactccccttgtgtcctcctcactcccagttgcttcctgg tggagaagcagcccccccaggtactgaagactcagaccaagttccaggctggagttcgattcctgttgggcttgaggttc ctgggggccccagccaagcctccgctggtcagggccgacatggtgacagagaagcaggcgcgggagctgagtgtgcctca gggtcctggggctggagcgtaagctgggattggacctggggttggagaagggctgttagggtgatggaggcagcctggag ggctggcactgaaaagagcaagggatggggagggagggccatgggatgtggagaccctgaatggtcaaggcagaggaaag ggagggacccatttagggctggaatggggtgggggcatcatgatttggccaagatggggactcctcccttaagaacccaa acagagacatggagatttagggctggtgacagtgggtagtctacactcacccatgcactcgccacacctgacgacagtga gatgagctcgttcacactctgacctcccctgggcagagaaagcactggagaaatcatcaacaacactgtgcccttggaga acagcattcctgggaactgctgctctgccctgttcaagaacctggtgaggggctttggggtgcagtgaggggggcaccac taggagactgtgggactctccttggagaggatgtcaggaagcccaggaggagcggtctctgtcctcatgacctcgccctt gctctccctcaccccacccacagcttctcaagaagatcaagcggtgtgagcggaagggcactgagtctgtcacagaggag aagtgcgctgtgctcttctctgccagcttcacacttggccccggcaaactccccatccagctccaggtgaaccgtggccc agccctgccccaatctgggaccccgagtcctcctccaatgccacgcacaagggccctggaccctcacctcttgtgactgc cccataccccatgtgtctgggattcatgcacactggggcccgggtgagtgggggtgagcaagagcatggagtgcacaggg cagggaatggtagtggatagcagcaaacacttcggaagcacttcctatagaccaggggcactctattaaatgatacatac tgcacatgcgtgccagcacacacacgtctggttttcacaataacattatgaggtaggcagtattatcagcctcattttat agcatgaggacattgagacagagagtttaagtagtttgtcccagtcacccagctaagtgttggagctggtatctgaaacc tggaagtctggttccatagcgattatagtaaccacttctctacggtgaggccctgattgagcttcaaaacgcatttaata acatggggaaagaaagaaagaaaagaaaccctgtcctcaccctacttcaggccctgtctctgcccctggtggtcatcgtc catggcaaccaagacaacaatgccaaagccactatcctgtgggacaatgccttctctgagatggtgaggaaagtccttgg tagttggagggaacagggtgcagggtgggttctaacatgggcagtggtgcaggcctgctgatggggtggtgggcatgtcg gatgggtgtgaccttaacacttcttcatgggcctgctttcgtgcttctgacctcttttcaccccagtcttaacaactatc aggccacagcactgtaacctagaaaaaacagcatgtttgtgagcgatatcaggggctgtggaggggtaggccacaggcat gtgggacggatgaaggccggcccgaggaataacaagacggtagcctgcagtgctctcttcttcccccttctccccaggac cgcgtgccctttgtggtggctgagcgggtgccctgggagaagatgtgtgaaactctgaacctgaagttcatggctgaggt ggggaccaaccgggggctgctcccagagcacttcctcttcctggcccagaagatcttcaatgacaacagcctcagtatgg aggccttccagcaccgttctgtgtcctggtcgcagttcaacaaggttcagttctccgcggccgcgagctctaatacgact cactatagggcgtcgactcgatcataccactgcactcaagcctgggtgacagagcaagactctgtctcaaaaaaaaaaaa aaaaaaaggccaggcatggtggttcatgcctgtaatcccagcactttgggaggccgagacggatagatcacctgaggtca ggagttcgagaccagcctggccaacatggcaaaaccccgtctctactaaaaacaaaaaaatagccaggatggtcgtttgc gtctgtaatcccagctactcggctgaggcaggaggtgaacccaggaggtaaaggctgcaggggaagatgaaaccattgca ctccagcctgggcaagactctgtatcaaaaaaaaaaaaaaaaaggctaggtgtggtggctcacacctgtaatcccagcac tttgggaggctgaggcgggcggatcacaaggtcaagaaatcgagaccatcctgaccaacatggtgaaaccccgtctctac taaaaatacaaaaattacctgggcatggtggcgcatgcctgtattcccaactactcgggaggctgaggcatgaaaatcac ttgaacctgggaggcagaggttgcaggcgagccaagattgtgccactgcactccagcctgccaacaaaaatgagattctg tcggttaccttccctttgggcgtcaacttctgccacacctccttagggagagggtgtagcatagtagttaagaggggtcc agggccagaatgcctgggtttaaatcctagctctgcctcttaccagctatgtagacctgggcaagtcattcgacgttttt ggacttccatttcttcatctgtaagatggaattattataatccctacttccatagcctggtaaagagcaaataaatatat ggaaaggcttgaaatagtggctggcacgtgtaagcattaggattggtcgttgtcattgatggagtctcaggttcggtctg atcctcagcccctgtgattctgtcgtgagggcactcacagctcactgcctgccctaaacaggctccagctctggccctcc ctcggctcacacctttccccctctccccctaggagatcctgctgggccgtggcttcaccttttggcagtggtttgatggt gtcctggacctcaccaaacgctgtctccggagctactggtctgaccggtgagtccccaccctgggtagtttgagcagcca tacaccagtcacctccatactcactgcccatgccccatcctctcct catcccggccaggctgatcattggcttcatcag caaacagtacgttactagccttcttctcaatgagcccgacggaacctttctcctccgcttcagcgactcagagattgggg gcatcaccattgcccatgtcatccggggccaggatggtgaggccaccccagccagtcctctgtctctgtgcctgtgccct ctggggtttcttctgggaatgaaatgtcctgaccttcctgatgccgatcctgatcttcaggaagttcttccagcttctct tcttccttctgtggtctaaatgttcaccttctcactgtgagctctgtgggaacggagactagtgggtctctctccctcag gagccccaccctaggtcctctctcccttgccttggtggagtgagaacaggtcttatggtaggggttggggaaggggaaga aatccggacagagggatctcagggtctccttcctaccataggctctccacagatagagaacatccagccattctctgcca aagacctgtccattcgctcactgggggaccgaatccgggatcttgctcagctcaaaaatctctatcccaagaagcccaag gatgaggctttccggagccactacaagcgtgagctggaactggcagctctgattccttcctgtcacccacttcctgccat gctccccgctgccatcctctccccagcccgtgagttatcctgaggtcactccgaatttccatagctgtgcttttcttact tcccggatgatccatgcccaccttttccacctcccttcctccctaacccgagagcaatccatggcagtcttttccatctc acaacagctgaacagctgaacagatgggtaaggatggcaggggttatgtcccagctaccatcaagatgaccgtggaaagg tgagtgtggtggtatggacagtgggtaggtcaggggcttagtgcttatctgcaggaaggaggggtggcatcaacccttgg tcagtcacatgtacctccttccctcctccagggaccaaccacttcctaccccagagctccagatgcctaccatggtgcct tcttatgaccttggaatggcccctgattcctccatgagcatgcagcttggcccagatatggtgtaaggagctggaaagac aggaatgggagtggtctgtgcagatgggctaatcttagcatgggcagctgggagagctggcactgggggctgaacaggga atcttcctttccatgagagggacacctgttcaaaagcagggtgtggtggtgtccaggagaagggctggcatcagggggtc tgttttctttccccaggccccaggtgtacccaccacactctcactccatccccccgtatcaaggcctctccccagaagaa tcagtcaacgtgttgtcagccttccaggagtaagtgaaaaacctcatggggataccatcccactctaagggggtgggcat ttgaattgttagaagaggctcttctgtgagaaaggagcagcaaatgctaacagcctgtcttcttctcttctgtccactct aatgagggggtagtagttaagatctggactgcctaggtttgaattctagctccaccacttactggtttggggcaaattac ttagcctttggtgccttatctgcacaatgggggataataatgctaataataataacctacctcactgcattattgtggag attaaatgagttcataacacttaaaaagctcgagcatagtgcatggctcatagcaaaagctgtgtaagtccagtcgtgga tcacttaatgaaggagcattttctgtctttggcagtttcataattatgcggaataccattgagtataattacacaaacct agatggtatagactactatacactgaggctatattgtgtagcctattgatcctagctttaaacccgagcagcatgatact gttctgaatagtataaggaaatagtaacataatggtaaatatttgtgtgataggaattttcagcttgattataatttttt ttttttgagacagggtctcactcactggagtgcagtggtgcgatcttagctcccctgcaacctccgcctcttgggctcga gcaatcctcctgctgtagtgcaccacgacactcggctaattcttttttaagatttttctgcagacaaggtctcacttact gcccaagctggtctcaaactcctgggcttaagtgatcctcccacctcggcctcccaaagcgttaggattacaggcgtgag tcactctgcctggccttgattataatcttatgggaccactgtggtctgtagttgacagaaatgtcgttaatgtggtgcat gactgttattattattttctgtcctgcccctgagagccactgtcacttctctgctgtattggtttttgtttactcatctg ttttggccttgaaatggcctagacatttttcttcccgaagtatgacactcgggtgcttattaacttagtcaagacacaac atctcccttcccagaaagtgaggcgggagtgaggacttggggacttaagaactaccaaagttcagagtccaaaggaaaca ttagaaattgggtaatccacccccataacacgcacattttacagatgagaagactgagctcagagcatagaaatagcttg cccaggccatgactaagtcaggataaggagctggagcttgtttcctcactcagtggtcctgactttgcaccactctgcat ttgcctagcctgccttcctctaactgtgctctccctacttccaggcctcacctgcagatgccccccagcctgggccagat gaacctgccctttgaccagcctcacccccaggtgaatgacaaaagcccctcctgacccatgtgcctcttctttcctgggc cttgcccgctctccttatttccattgctggttcctggcagggcctgctgccgtgccagcctcaggagcatgctgtgtcca gccctgaccccctgctctgctcagatgtgaccatggtggaagacagctgcctgagccagccagtgacagcgtttcctcag ggcacttggtgagtggcagcttgggagtggaggctgggtggcatctaggggagtgggcgccatgcctactccactgcttc tcccatctccttgcaggattggtgaagacatattccctcctctgctgcctcccactgaacaggacctcactaagcttctc ctggaggggcaaggggagtcggggggagggtccttgggggcacagcccctcctgcagccctcccactatgggcaatctgg gatctcaatgtcccacatggacctaagggccaaccccagttggtgatcccagctggagggagaacccaaagagacagctc ttctactacccccacagacctgctctggacacttgctcatgccctgccaagcagcagatggggagggtgccctcctatcc ccacctactcctgggtcaggaggaaaagactaacaggagaatgcacagtgggtggagccaatccactccttcctttctat cattcccctgcccacctccttccagcactgactggaagggaagttcaggctctgagacacgccccaacatgcctgcacct gcagcgcgcacacgcacgcacacacacatacagagctctctgagggtgatggggctgagcaggaggggggctgggtaaga gcacaggttagggcatggaaggcttctccgcccattctgacccagggcctaggacggataggcaggaacatacagacaca tttacactagaggccagggatagaggatattgggtctcagccctaggggaatgggaagcagctgaagggaccctgggtgg gagcataggaggagtctggacatgtggttactagtacaggttttgccctgattaaaaaatctcccaaagccccaaattcc tgttagccaggtggaggcttctgatacgtgtatgagactatgcaaaagtacaagggctgagattcttcgtgtatagctgt gtgaacgtgtatgtacctaggatatgttaaatatatagctggcaccttagttgcatgaccacatagaacatgtgtctatc tgcttttgcctacgtgacaacacaaatttgggagggtgagacactgcacagaagacagcagcaagtgtgctggcctctct gacatatgctaacccccaaatactctgaatttggagtctgactgtgcccaagtgggtccaagtggctgtgacatctacgt atggctccacacctccaatgctgcctgggagccagggtgagagtctgggtccaggcctggccatgtggccctccagtgta tgagagggccctgcctgctgcatcttttctgttgccccatccaccgccagcttcccttcactcccctatcccattctccc tctcaaggcaggggtcatagatcctaagccataaaataaattttattccaaaataacaaaataaataatctactgtacac aatctgaaaagaaagacgctctaactgctcagataggtgctgcggtccagcccccagctggaggagaccctgagtccaac ccaggcctcccgagggggccagtgaagggatcccacacccaccgcccctatgtagggcagggaagaaattgcaaaggact tgggggatagatgggaatgggagggcaaactgcagcacttgttaaattaattaaagaaacaaaccagaagcacaaaaacg gggaaggagaagggagaaggagcaggtccagtgttccaggccccaattctgggggcaaatgtgccagcagcacctatctg agcagttagagcgtctttcttttcagattgtgtacagtagattatttattttgttattttggaataaaatttattttatg gcttaggatctatgacccctgccttgagagggagaatgggataggggagtgaagggaagctggcggtggatggggcaaca gaaaagatgcagcaggcagggccctctcatacactggagggccacatggccaggcctggacccagactctcaccctggct cccaggcagcattggaggtgtggagccatacgtagatgtcacagccacttggacccacttgggcacagtcagactccaaa ttcagagtatttgggggttagcatatgtcagagaggccagcacacttgctgctgtcttctgtgcagtgtctcaccctccc aaatttgtgttgtcacgtaggcaaaagcagatagacacatgttctatgtggtcatgcaactaaggtgccagctatacatt taacatatcctaggtacatacacgttcacacagctatacacgaagaatctcagcccttgtacttttgcatagtctcatac acgtatcagaagcctccacctggctaacaggaatttggggctttgggagattttttaatcagggcaaaacctgtactagt aaccacatgtccagacccctcctatgctcccacccagggtcccttgagctgcttcccattcccctagggctgagacccaa tatcctctatccctggcctctagtgtaaatgtgtctgtatgttcctgcctatccgtcctaggccctgggtcagaatgggc ggagaagccttccatgccctaacctgtgctcttacccagcccccctcctgctcagccccatcaccctcagagagctctgt atgtgtgtgtgcgtgcgtgtgcgcgctgcaggtgcaggcatgttggggtgtgtctcagagcctgaacttcccttccagtc agtactggaaggaggtgggcaggggaatgatagaaaggaaggagtggattggctccacccactgtgcattctcctgttag tcttttcctcctgacccaggagtaggtggggataggagggcaccctccccatctgctgcttggcagggcatgagcaagtg tccagagcaggtctgtgggggtagtagaagagctgtctctttgggttctccctccagctgggatcaccaactggggttgg cccttaggtccatgtgggacattgagatcccagattgcccatagtgggagggctgcaggaggggctgtgcccccaaggac cctccccccgactccccttgcccctccaggagaagcttagtgaggtcctgttcagtgggaggcagcagaggagggaatat gtcttcaccaatcctgcaaggagatgggagaagcagtggagtaggcatggcgcccactcccctagatgccacccagcctc cactcccaagctgccactcac (SEQ ID NO: 12181) cgccatcccgcgctctgcggactgggaggcccgggccaggacgcgagtctgcgcagccgaggttccccagcgccccctgc agccgcgcgtaggcagagacggagcccggccctgcgcctccgcaccacgcccgggaccccacccagcggcccgtacccgg agaagcagcgcgagcacccgaagctcccggctcggcggcagaaaccgggagtggggccgggcgagtgcgcggcatcccag gccggcccgaacgtccgcccgcggtgggccgacttcccctcctcttccctctctccttcctttagcccgctggcgccgga cacgctgcgcctcatctcttggggcgttcttccccgttggccaaccgtcgcatcccgtgcaactttggggtagtggccgc ttagtgttgaatgttccccaccgagagcgcatggcttgggaagcgaggcgcgaacccgggccccgaagccgccgtccggg agacggtgatgctgttgctgtgcctgggggtcccgaccggccgcccctacaacgtggacactgagagcgcgctgctttac cagggcccccacaacacgctgttcggctactcggtcgtgctgcacagccacggggcgaaccgatggctcctagtgggtgc gcccactgccaactggctcgccaacgcttcagtgatcaatcccggggcgatttacagatgcaggatcggaaagaatcccg gccagacgtgcgaacagctccagctgggtagccctaatggagaaccttgtggaaagacttgtttggaagagagagacaat cagtggttgggggtcacactttccagacagccaggagaaaatggatccatcgtgacttgtgggcatagatggaaaaatat attttacataaagaatgaaaataagctccccactggtggttgctatggagtgccccctgatttacgaacagaactgagta aaagaatagctccgtgttatcaagattatgtgaaaaaatttggagaaaattttgcatcatgtcaagctggaatatccagt ttttacacaaaggatttaattgtgatgggggccccaggatcatcttactggactggctctctttttgtctacaatataac tacaaataaatacaaggcttttttagacaaacaaaatcaagtaaaatttggaagttatttaggatattcagtcggagctg gtcattttcggagccagcatactaccgaagtagtcggaggagctcctcaacatgagcagattggtaaggcatatatattc agcattgatgaaaaagaactaaatatcttacatgaaatgaaaggtaaaaagcttggatcgtactttggagcttctgtctg tgctgtggacctcaatgcagatggcttctcagatctgctcgtgggagcacccatgcagagcaccatcagagaggaaggaa gagtgtttgtgtacatcaactctggctcgggagcagtaatgaatgcaatggaaacaaacctcgttggaagtgacaaatat gctgcaagatttggggaatctatagttaatcttggcgacattgacaatgatggctttgaagatgttgctatcggagctcc acaagaagatgacttgcaaggtgctatttatatttacaatggccgtgcagatgggatctcgtcaaccttctcacagagaa ttgaaggacttcagatcagcaaatcgttaagtatgtttggacagtctatatcaggacaaattgatgcagataataatggc tatgtagatgtagcagttggtgcttttcggtctgattctgctgtcttgctaaggacaagacctgtagtaattgttgacgc ttctttaagccaccctgagtcagtaaatagaacgaaatttgactgtgttgaaaatggatggccttctgtgtgcatagatc taacactttgtttctcatataagggcaaggaagttccaggttacattgttttgttttataacatgagtttggatgtgaac agaaaggcagagtctccaccaagattctatttctcttctaatggaacttctgacgtgattacaggaagcatacaggtgtc cagcagagaagctaactgtagaacacatcaagcatttatgcggaaagatgtgcgggacatcctcaccccaattcagattg aagctgcttaccaccttggtcctcatgtcatcagtaaacgaagtacagaggaattcccaccacttcagccaattcttcag cagaagaaagaaaaagacataatgaaaaaaacaataaactttgcaaggttttgtgcccatgaaaattgttctgctgattt acaggtttctgcaaagattgggtttttgaagccccatgaaaataaaacatatcttgctgttgggagtatgaagacattga tgttgaatgtgtccttgtttaatgctggagatgatgcatatgaaacgactctacatgtcaaactacccgtgggtctttat ttcattaagattttagagctggaagagaagcaaataaactgtgaagtcacagataactctggcgtggtacaacttgactg cagtattggctatatatatgtagatcatctctcaaggatagatattagctttctcctggatgtgagctcactcagcagag cggaagaggacctcagtatcacagtgcatgctacctgtgaaaatgaagaggaaatggacaatctaaagcacagcagagtg actgtagcaatacctttaaaatatgaggttaagctgactgttcatgggtttgtaaacccaacttcatttgtgtatggatc aaatgatgaaaatgagcctgaaacgtgcatggtggagaaaatgaacttaactttccatgttatcaacactggcaatagta tggctcccaatgttagtgtggaaataatggtaccaaattcttttagcccccaaactgataagctgttcaacattttggat gtccagactactactggagaatgccactttgaaaattatcaaagagtgtgtgcattagagcagcaaaagagtgcaatgca gaccttgaaaggcatagtccagttcttgtccaagactgataagaggctattgtactgcataaaagctgatccacattgtt taaatttcttgtgtaattttgggaaaatggaaagtggaaaagaagccagtgttcatatccaactggaaggccggccatcc attttagaaatggatgagacttcagcactcaagtttgaaataagagcaacaggttttccagagccaaatccaagagtaat tgaactaaacaaggatgagaatgttgcgcatgttctactggaaggactacatcatcaaagacccaaacgttatttcacca tagtgattatttcaagtagcttgctacttggacttattgtacttctgttgatctcatatgttatgtggaaggctggcttc tttaaaagacaatacaaatctatcctacaagaagaaaacagaagagacagttggagttatatcaacagtaaaagcaatga tgattaaggacttctttcaaattgagagaatggaaaacagcccgccc (SEQ ID NO:12182) gaattccgggccgcttagtgttgaatgttccccaccgagagcgcatggcttgggaagcgaggcgcgaacccgggccccga agccgccgtccgggagacggtgatgctgttgctgtgcctgggggtcccgaccggccgcccctacaacgtggacactgaga gcgcgctgctttaccagggcccccacaacacgctgttcggctactcggtcgtgctgcacagccacggggcgaaccgatgg ctcctagtgggtgcgcccactgccaactggctcgccaacgcttcagtgatcaatcccggggcgatttacagatgcaggat cggaaagaatcccggccagacgtgcgaacagctccagctgggtagccctaatggagaaccttgtggaaagacttgtttgg aagagagagacaatcagtggttgggggtcacactttccagacagccaggagaaaatggatccatcgtgacttgtgggcat agatggaaaaatatattttacataaagaatgaaaataagctccccactggtggttgctatggagtgccccctgatttacg aacagaactgagtaaaagaatagctccgtgttatcaagattatgtgaaaaaatttggagaaaattttgcatcatgtcaag ctggaatatccagtttttacacaaaggatttaattgtgatgggggccccaggatcatcttactggactggctctcttttt gtctacaatataactacaaataaatacaaggcttttttagacaaacaaaatcaagtaaaatttggaagttatttaggata ttcagtcggagctggtcattttcggagccagcatactaccgaagtagtcggaggagctcctcaacatgagcagattggta aggcatatatattcagcattgatgaaaaagaactaaatatcttacatgaaatgaaaggtaaaaagcttggatcgtacttt ggagcttctgtctgtgctgtggacctcaatgcagatggcttctcagatctgctcgtgggagcacccatgcagagcaccat cagagaggaaggaagagtgtttgtgtacatcaactctggctcgggagcagtaatgaatgcaatggaaacaaacctcgttg gaagtgacaaatatgctgcaagatttggggaatctatagttaatcttggcgacattgacaatgatggctttgaagatgtt gctatcggagctccacaagaagatgacttgcaaggtgctatttatatttacaatggccgtgcagatgggatctcgtcaac cttctcacagagaattgaaggacttcagatcagcaaatcgttaagtatgtttggacagtctatatcaggacaaattgatg cagataataatggctatgtagatgtagcagttggtgcttttcggtctgattctgctgtcttgctaaggacaagacctgta gtaattgttgacgcttctttaagccaccctgagtcagtaaatagaacgaaatttgactgtgttgaaaatggatggccttc tgtgtgcatagatctaacactttgtttctcatataagggcaaggaagttccaggttacattgttttgttttataacatga gtttggatgtgaacagaaaggcagagtctccaccaagattctatttctcttctaatggaacttctgacgtgattacagga agcatacaggtgtccagcagagaagctaactgtagaacacatcaagcatttatgcggaaagatgtgcgggacatcctcac cccaattcagattgaagctgcttaccaccttggtcctcatgtcatcagtaaacgaagtacagaggaattcccaccacttc agccaattcttcagcagaagaaagaaaaagacataatgaaaaaaacaataaactttgcaaggttttgtgcccatgaaaat tgttctgctgatttacaggtttctgcaaagattgggtttttgaagccccatgaaaataaaacatatcttgctgttgggag tatgaagacattgatgttgaatgtgtccttgtttaatgctggagatgatgcatatgaaacgactctacatgtcaaactac ccgtgggtctttatttcattaagattttagagctggaagagaagcaaataaactgtgaagtcacagataactctggcgtg gtacaacttgactgcagtattggctatatatatgtagatcatctctcaaggatagatattagctttctcctggatgtgag ctcactcagcagagcggaagaggacctcagtatcacagtgcatgctacctgtgaaaatgaagaggaaatggacaatctaa agcacagcagagtgactgtagcaatacctttaaaatatgaggttaagctgactgttcatgggtttgtaaacccaacttca tttgtgtatggatcaaatgatgaaaatgagcctgaaacgtgcatggtggagaaaatgaacttaactttccatgttatcaa cactggcaatagtatggctcccaatgttagtgtggaaataatggtaccaaattcttttagcccccaaactgataagctgt tcaacattttggatgtccagactactactggagaatgccactttgaaaattatcaaagagtgtgtgcattagagcagcaa aagagtgcaatgcagaccttgaaaggcatagtccggttcttgtccaagactgataagaggctattgtactgcataaaagc tgatccacattgtttaaatttcttgtgtaattttgggaaaatggaaagtggaaaagaagccagtgttcatatccaactgg aaggccggccatccattttagaaatggatgagacttcagcactcaagtttgaaataagagcaacaggttttccagagcca aatccaagagtaattgaactaaacaaggatgagaatgttgcgcatgttctactggaaggactacatcatcaaagacccaa acgttatttcaccatagtgattatttcaagtagcttgctacttggacttattgtacttctgttgatctcatatgttatgt ggaaggctggcttctttaaaagacaatacaaatctatcctacaagaagaaaacagaagagacagttggagttatatcaac agtaaaagcaatgatgattaaggacttctttcaaattgagagaatggaaaacagactcaggttgtagtaaagaaatttaa aagacactgtttacaagaaaaaatgaattttgtttggacttcttttactcatgatcttgtgacatattatgtcttcatgc aaggggaaaatctcagcaatgattactctttgagatagaagaactgcaaaggtaataatacagccaaagataatctctca gcttttaaatgggtagagaaacactaaagcattcaatttattcaagaaaagtaagcccttgaagatatcttgaaatgaaa g ataactgagttaaattatactggagaagtcttagacttgaaatactacttaccatatgtgcttgcctcagtaaaatga accccactgggtgggcagaggttcatttcaaatacatctttgatacttgttcaaaatatgttctttaaaaatataatttt ttagagagctgttcccaaattttctaacgagtggaccattatcactttaaagccctttatttataatacatttcctacgg gctgtgttccaacaaccattttttttcagcagactatgaatattatagtattataggccaaactggcaaacttcagactg aacatgtacactggtttgagcttagtgaaatgacttccggaatct (SEQ ID NO: 12183) cgccatcccgcgctctgcggactgggaggcccgggccaggacgcgagtctgcgcagccgaggttccccagcgccccctgc agccgcgcgtaggcagagacggagcccggccctgcgcctccgcaccacgcccgggaccccacccagcggcccgtacccgg agaagcagcgcgagcacccgaagctcccggctcggcggcagaaaccgggagtggggccgggcgagtgcgcggcatcccag gccggcccgaacgtccgcccgcggtgggccgacttcccctcctcttccctctctccttcctttagcccgctggcgccgga cacgctgcgcctcatctcttggggcgttcttccccgttggccaaccgtcgcatcccgtgcaactttggggtagtggccgc ttagtgttgaatgttccccaccgagagcgcatggcttgggaagcgaggcgcgaacccgggccccgaagccgccgtccggg agacggtgatgctgttgctgtgcctgggggtcccgaccggccgcccctacaacgtggacactgagagcgcgctgctttac cagggcccccacaacacgctgttcggctactcggtcgtgctgcacagccacggggcgaaccgatggctcctagtgggtgc gcccactgccaactggctcgccaacgcttcagtgatcaatcccggggcgatttacagatgcaggatcggaaagaatcccg gccagacgtgcgaacagctccagctgggtagccctaatggagaaccttgtggaaagacttgtttggaagagagagacaat cagtggttgggggtcacactttccagacagccaggagaaaatggatccatcgtgacttgtgggcatagatggaaaaatat attttacataaagaatgaaaataagctccccactggtggttgctatggagtgccccctgatttacgaacagaactgagta aaagaatagctccgtgttatcaagattatgtgaaaaaatttggagaaaattttgcatcatgtcaagctggaatatccagt ttttacacaaaggatttaattgtgatgggggccccaggatcatcttactggactggctctctttttgtctacaatataac tacaaataaatacaaggcttttttagacaaacaaaatcaagtaaaatttggaagttatttaggatattcagtcggagctg gtcattttcggagccagcatactaccgaagtagtcggaggagctcctcaacatgagcagattggtaaggcatatatattc agcattgatgaaaaagaactaaatatcttacatgaaatgaaaggtaaaaagcttggatcgtactttggagcttctgtctg tgctgtggacctcaatgcagatggcttctcagatctgctcgtgggagcacccatgcagagcaccatcagagaggaaggaa gagtgtttgtgtacatcaactctggctcgggagcagtaatgaatgcaatggaaacaaacctcgttggaagtgacaaatat gctgcaagatttggggaatctatagttaatcttggcgacattgacaatgatggctttgaagatgttgctatcggagctcc acaagaagatgacttgcaaggtgctatttatatttacaatggccgtgcagatgggatctcgtcaaccttctcacagagaa ttgaaggacttcagatcagcaaatcgttaagtatgtttggacagtctatatcaggacaaattgatgcagataataatggc tatgtagatgtagcagttggtgcttttcggtctgattctgctgtcttgctaaggacaagacctgtagtaattgttgacgc ttctttaagccaccctgagtcagtaaatagaacgaaatttgactgtgttgaaaatggatggccttctgtgtgcatagatc taacactttgtttctcatataagggcaaggaagttccaggttacattgttttgttttataacatgagtttggatgtgaac agaaaggcagagtctccaccaagattctatttctcttctaatggaacttctgacgtgattacaggaagcatacaggtgtc cagcagagaagctaactgtagaacacatcaagcatttatgcggaaagatgtgcgggacatcctcaccccaattcagattg aagctgcttaccaccttggtcctcatgtcatcagtaaacgaagtacagaggaattcccaccacttcagccaattcttcag cagaagaaagaaaaagacataatgaaaaaaacaataaactttgcaaggttttgtgcccatgaaaattgttctgctgattt acaggtttctgcaaagattgggtttttgaagccccatgaaaataaaacatatcttgctgttgggagtatgaagacattga tgttgaatgtgtccttgtttaatgctggagatgatgcatatgaaacgactctacatgtcaaactacccgtgggtctttat ttcattaagattttagagctggaagagaagcaaataaactgtgaagtcacagataactctggcgtggtacaacttgactg cagtattggctatatatatgtagatcatctctcaaggatagatattagctttctcctggatgtgagctcactcagcagag cggaagaggacctcagtatcacagtgcatgctacctgtgaaaatgaagaggaaatggacaatctaaagcacagcagagtg actgtagcaatacctttaaaatatgaggttaagctgactgttcatgggtttgtaaacccaacttcatttgtgtatggatc aaatgatgaaaatgagcctgaaacgtgcatggtggagaaaatgaacttaactttccatgttatcaacactggcaatagta tggctcccaatgttagtgtggaaataatggtaccaaattcttttagcccccaaactgataagctgttcaacattttggat gtccagactactactggagaatgccactttgaaaattatcaaagagtgtgtgcattagagcagcaaaagagtgcaatgca gaccttgaaaggcatagtccagttcttgtccaagactgataagaggctattgtactgcataaaagctgatccacattgtt taaatttcttgtgtaattttgggaaaatggaaagtggaaaagaagccagtgttcatatccaactggaaggccggccatcc attttagaaatggatgagacttcagcactcaagtttgaaataagagcaacaggttttccagagccaaatccaagagtaat tgaactaaacaaggatgagaatgttgcgcatgttctactggaaggactacatcatcaaagacccaaacgttatttcaeca tagtgattatttcaagtagcttgctacttggacttattgtacttctgttgatctcatatgttatgtggaaggctggcttc tttaaaagacaatacaaatctatcctacaagaagaaaacagaagagacagttggagttatatcaacagtaaaagcaatga tgattaaggacttctttcaaattgagagaatggaaaacagcccgcccgaattccgggccgcttagtgttgaatgttcccc accgagagcgcatggcttgggaagcgaggcgcgaacccgggccccgaagccgccgtccgggagacggtgatgctgttgct gtgcctgggggtcccgaccggccgcccctacaacgtggacactgagagcgcgctgctttaccagggcccccacaacacgc tgttcggctactcggtcgtgctgcacagccacggggcgaaccgatggctcctagtgggtgcgcccactgccaactggctc gccaacgcttcagtgatcaatcccggggcgatttacagatgcaggatcggaaagaatcccggccagacgtgcgaacagct ccagctgggtagccctaatggagaaccttgtggaaagacttgtttggaagagagagacaatcagtggttgggggtcacac tttccagacagccaggagaaaatggatccatcgtgacttgtgggcatagatggaaaaatatattttacataaagaatgaa aataagctccccactggtggttgctatggagtgccccctgatttacgaacagaactgagtaaaagaatagctccgtgtta tcaagattatgtgaaaaaatttggagaaaattttgcatcatgtcaagctggaatatccagtttttacacaaaggatttaa ttgtgatgggggccccaggatcatcttactggactggctctctttttgtctacaatataactacaaataaatacaaggct tttttagacaaacaaaatcaagtaaaatttggaagttatttaggatattcagtcggagctggtcattttcggagccagca tactaccgaagtagtcggaggagctcctcaacatgagcagattggtaaggcatatatattcagcattgatgaaaaagaac taaatatcttacatgaaatgaaaggtaaaaagcttggatcgtactttggagcttctgtctgtgctgtggacctcaatgca gatggcttctcagatctgctcgtgggagcacccatgcagagcaccatcagagaggaaggaagagtgtttgtgtacatcaa ctctggctcgggagcagtaatgaatgcaatggaaacaaacctcgttggaagtgacaaatatgctgcaagatttggggaat ctatagttaatcttggcgacattgacaatgatggctttgaagatgttgctatcggagctccacaagaagatgacttgcaa ggtgctatttatatttacaatggccgtgcagatgggatctcgtcaaccttctcacagagaattgaaggacttcagatcag caaatcgttaagtatgtttggacagtctatatcaggacaaattgatgcagataataatggctatgtagatgtagcagttg gtgcttttcggtctgattctgctgtcttgctaaggacaagacctgtagtaattgttgacgcttctttaagccaccctgag tcagtaaatagaacgaaatttgactgtgttgaaaatggatggccttctgtgtgcatagatctaacactttgtttctcata taagggcaaggaagttccaggttacattgttttgttttataacatgagtttggatgtgaacagaaaggcagagtctccac caagattctatttctcttctaatggaacttctgacgtgattacaggaagcatacaggtgtccagcagagaagctaactgt agaacacatcaagcatttatgcggaaagatgtgcgggacatcctcaccccaattcagattgaagctgcttaccaccttgg tcctcatgtcatcagtaaacgaagtacagaggaattcccaccacttcagccaattcttcagcagaagaaagaaaaagaca taatgaaaaaaacaataaactttgcaaggttttgtgcccatgaaaattgttctgctgatttacaggtttctgcaaagatt gggtttttgaagccccatgaaaataaaacatatcttgctgttgggagtatgaagacattgatgttgaatgtgtccttgtt taatgctggagatgatgcatatgaaacgactctacatgtcaaactacccgtgggtctttatttcattaagattttagagc tggaagagaagcaaataaactgtgaagtcacagataactctggcgtggtacaacttgactgcagtattggctatatatat gtagatcatctctcaaggatagatattagctttctcctggatgtgagctcactcagcagagcggaagaggacctcagtat cacagtgcatgctacctgtgaaaatgaagaggaaatggacaatctaaagcacagcagagtgactgtagcaatacctttaa aatatgaggttaagctgactgttcatgggtttgtaaacccaacttcatttgtgtatggatcaaatgatgaaaatgagcct gaaacgtgcatggtggagaaaatgaacttaactttccatgttatcaacactggcaatagtatggctcccaatgttagtgt ggaaataatggtaccaaattcttttagcccccaaactgataagctgttcaacattttggatgtccagactactactggag aatgccactttgaaaattatcaaagagtgtgtgcattagagcagcaaaagagtgcaatgcagaccttgaaaggcatagtc cggttcttgtccaagactgataagaggctattgtactgcataaaagctgatccacattgtttaaatttcttgtgtaattt tgggaaaatggaaagtggaaaagaagccagtgttcatatccaactggaaggccggccatccattttagaaatggatgaga cttcagcactcaagtttgaaataagagcaacaggttttccagagccaaatccaagagtaattgaactaaacaaggatgag aatgttgcgcatgttctactggaaggactacatcatcaaagacccaaacgttatttcaccatagtgattatttcaagtag cttgctacttggacttattgtacttctgttgatctcatatgttatgtggaaggctggcttctttaaaagacaatacaaat ctatcctacaagaagaaaacagaagagacagttggagttatatcaacagtaaaagcaatgatgattaaggacttctttca aattgagagaatggaaaacagactcaggttgtagtaaagaaatttaaaagacactgtttacaagaaaaaatgaattttgt ttggacttcttttactcatgatcttgtgacatattatgtcttcatgcaaggggaaaatctcagcaatgattactctttga gatagaagaactgcaaaggtaataatacagccaaagataatctctcagcttttaaatgggtagagaaacactaaagcatt caatttattcaagaaaagtaagcccttgaagatatcttgaaatgaaagtataactgagttaaattatactggagaagtct tagacttgaaatactacttaccatatgtgcttgcctcagtaaaatgaaccccactgggtgggcagaggttcatttcaaat acatctttgatacttgttcaaaatatgttctttaaaaatataattttttagagagctgttcccaaattttctaacgagtg gaccattatcactttaaagccctttatttataatacatttcctacgggctgtgttccaacaaccattttttttcagcaga ctatgaatattatagtattataggccaaactggcaaacttcagactgaacatgtacactggtttgagcttagtgaaatga cttccggaatct (SEQ ID NO: 12184) cagctgtccctccccactgccatttattccttccttcattcaaaccttatgtggctgctacttaccgtgtgttaagtgtt cactttttttcttggaattcaaaaaaagaaggacagtatttggggcacagatcttttggtgttctatacatttttttaaa gtttcattttacatttgtgtgtgcgtgtgtgtgtgtgtgtgagacagtcttgctctgttgcccaggctggagtgcagtgg cataatcattggctcactgtagcctcaaagtcctgggcccaagcgatcttcccacctcagccacccaaaatgctggggtt acaggtttatgccactctgtctgacctgaaagttttgggtttactttcccttctttctctttgctgaagtcagagatgat ggcagcttccagattctctggtgcctgtgctgggctcgtgctggtcatggtcttgggtccaggattcattctggagactc tcagggaagtttcccatgacaaggaaatgtaggagagtgtgctggctttgcgtgctcctctgccaagccctgcttctcct ggtgggacacactgaaccacagccagggcattttggtggttagttaaaaaaaaaaaaaaaaaaaaaaaggaagaagaagg cactgtgtaattgtgccggggatcttcagaaattgtaatgatgaaagagtgcaagctctcacttccccttcctgtacagg gcaggttgtgcagctggaggcagagcagtcctctctggggagcctgaagcaaacatggatcaagaaactgtaggcaatgt tgtcctgttggccatcgtcaccctcatcagcgtggtccagaatggtaaggaaagcccttcactcagggaagaacagaagg ggagattttctttgatggttgtttggaagtcaggcttaaacaattgtgtctgtgtgtgcgcatgcacaaacacttttacc ttatctttattttcttctttttatttgaatgtatagggttgtgtgtatttctgtgtaaatttggggttttcctcctctta gtctttcacttttgtggtgattaccagtcccatttttagagccagggctgcaacttgaaggttttgct (SEQ ID NO: 12185) tgcgttttgggggttcctggagtatcaatcatggatcaagaaactgtaggcaatgttgtcctgttggccatcgtcaccct catcagcgtggtccagaatggattctttgcccataaagtggagcacgaaagcaggacccagaatgggaggagcttccaga ggaccggaacacttgcctttgagcgggtctacactgccaaccagaactgtgtagatgcgtaccccactttcctcgctgtg ctctggtctgcggggctactttgcagccaagttcctgctgcgtttgctggactgatgtacttgtttgtgcggcaaaagta ctttgtcggttacctaggagagagaacgcagagcacccctggctacatatttgggaaacgcatcatactcttcctgttcc tcatgtccgttgctggcatattcaactattacctcatcttctttttcggaagtgactttgaaaactacataaagacgatc tccaccaccatctcccctctacttctcatttcctaactctctgctgaatatggggttggt (SEQ ID NO: 12186) atgccctcctacacggtcaccgtggccactggcagccagtggttcgccggcactgacgactacatctacctcagcctcgt gggctcggcgggctgcagcgagaagcacctgctggacaagcccttctacaacgacttcgagcgtggcgcggtggattcat acgacgtgactgtggacgaggaactgggcgagatccagctggtcagaatcgagaagcgcaagtactggctgaatgacgac tggtacctgaagtacatcacgctgaagacgccccacggggactacatcgagttcccctgctaccgctggatcaccggcga tgtcgaggttgtcctgagggatggacgcgcaaagttggcccgagatgaccaaattcacattctcaagcaacaccgacgta aagaactggaaacacggcaaaaacaatatcgatggatggagtggaaccctggcttccccttgagcatcgatgccaaatgc cacaaggatttaccccgtgatatccagtttgatagtgaaaaaggagtggactttgttctgaattactccaaagcgatgga gaacctgttcatcaaccgcttcatgcacatgttccagtcttcttggaatgacttcgccgactttgagaaaatctttgtca agatcagcaacactatttctgagcgggtcatgaatcactggcaggaagacctgatgtttggctaccagttcctgaatggc tgcaaccctgtgttgatccggcgctgcacagagctgcccgagaagctcccggtgaccacggagatggtagagtgcagcct ggagcggcagctcagcttggagcaggaggtccagcaagggaacattttcatcgtggactttgagctgctggatggcatcg atgccaacaaaacagacccctgcacactccagttcctggccgctcccatctgcttgctgtataagaacctggccaacaag attgtccccattgccatccagctcaaccaaatcccgggagatgagaaccctattttcctcccttcggatgcaaaatacga ctggcttttggccaaaatctgggtgcgttccagtgacttccacgtccaccagaccatcacccaccttctgcgaacacatc tggtgtctgaggtttttggcattgcaatgtaccgccagctgcctgctgtgcaccccattttcaagctgctggtggcacac gtgagattcaccattgcaatcaacaccaaggcccgtgagcagctcatctgcgagtgtggcctctttgacaaggccaacgc cacagggggcggtgggcacgtgcagatggtgcagagggccatgaaggacctgacctatgcctccctgtgctttcccgagg ccatcaaggcccggggcatggagagcaaagaagacatcccctactacttctaccgggacgacgggctcctggtgtgggaa gccatcaggacgttcacggccgaggtggtagacatctactacgagggcgaccaggtggtggaggaggacccggagctgca ggacttcgtgaacgatgtctacgtgtacggcatgcggggccgcaagtcctcaggcttccccaagtcggtcaagagccggg agcagctgtcggagtacctgaccgtggtgatcttcaccgcctccgcccagcacgccgcggtcaacttcggccagtacgac tggtgctcctggatccccaatgcgcccccaaccatgcgagccccgccaccgactgccaagggcgtggtgaccattgagca gatcgtggacacgctgcccgaccgcggccgctcctgctggcatctgggtgcagtgtgggcgctgagccagttccaggaaa acgagctgttcctgggcatgtacccagaagagcattttatcgagaagcctgtgaaggaagccatggcccgattccgcaag aacctcgaggccattgtcagcgtgattgctgagcgcaacaagaagaagcagctgccatattactacttgtccccagaccg gattccgaacagtgtggccatc (SEQ ID NO: 12187) gggcccggcgctcgctgctcccgcggcccgcgccatgccctcctacacggtcaccgtggccactggcagccagtggttcg ccggcactgacgactacatctacctcagcctcgtgggctcggcgggctgcagcgagaagcacctgctggacaagcccttc tacaacgacttcgagcgtggcgcggtggattcatacgacgtgactgtggacgaggaactgggcgagatccagctggtcag aatcgagaagcgcaagtactggctgaatgacgactggtacctgaagtacatcacgctgaagacgccccacggggactaca tcgagttcccctgctaccgctggatcaccggcgatgtcgaggttgtcctgagggatggacgcgcaaagttggcccgagat gaccaaattcacattctcaagcaacaccgactgaaagaactggaaacacggcaaaaacaatatcgatggatggagtggaa ccctggcttccccttgagcatcgatgccaaatgccacaaggatttaccccgtgatatccagtttgatagtgaaaaaggag tggactttgttctgaattactccaaagcgatggagaacctgttcatcaaccgcttcatgcacatgttccagtcttcttgg aatgacttcgccgactttgagaaaatctttgtcaagatcagcaacactatttctgagcgggtcatgaatcactggcagga agacctgatgtttggctaccagttcctgaatggctgcaaccctgtgttgatccggcgctgcacagagctgcccgagaagc tcccggtgaccacggagatggtagagtgcagcctggagcggcagctcagcttggagcaggaggtccagcaagggaacatt ttcatcgtggactttgagctgctggatggcatcgatgccaacaaaacagacccctgcacactccagttcctggccgctcc catctgcttgctgtataagaacctggccaacaagattgtccccattgccatccagctcaaccaaatcccgggagatgaga accctattttcctcccttcggatgcaaaatacgactggcttttggccaaaatctgggtgcgttccagtgacttccacgtc caccagaccatcacccaccttctgcgaacacatctggtgtctgaggtttttggcattgcaatgtaccgccagctgcctgc tgtgcaccccattttcaagctgctggtggcacacgtgagattcaccattgcaatcaacaccaaggcccgtgagcagctca tctgcgagtgtggcctctttgacaaggccaacgccacagggggcggtgggcacgtgcagatggtgcagagggccatgaag gacctgacctatgcctccctgtgctttcccgaggccatcaaggcccggggcatggagagcaaagaagacatcccctacta cttctaccgggacgacgggctcctggtgtgggaagccatcaggacgttcacggccgaggtggtagacatctactacgagg gcgaccaggtggtggaggaggacccggagctgcaggacttcgtgaacgatgtctacgtgtacggcatgcggggccgcaag tcctcaggcttccccaagtcggtcaagagccgggagcagctgtcggagtacctgaccgtggtgatcttcaccgcctccgc ccagcacgccgcggtcaacttcggccagtacgactggtgctcctggatccccaatgcgcccccaaccatgcgagccccgc caccgactgccaagggcgtggtgaccattgagcagatcgtggacacgctgcccgaccgcggccgctcctgctggcatctg ggtgcagtgtgggcgctgagccagttccaggaaaacgagctgttcctgggcatgtacccagaagagcattttatcgagaa gcctgtgaaggaagccatggcccgattccgcaagaacctcgaggccattgtcagcgtgattgctgagcgcaacaagaaga agcagctgccatattactacttgtccccagaccggattccgaacagtgtggccatctgagcacactgccagtctcactgt gggaaggccagctgccccagccagatggactccagcctgcctggcaggtgtctggccaggcctcttggcagtcacatctc ttcctccgaggccagtacctttccatttattctttgatcttcagggaactgcatagattgatcaaagtgtaaacaccata gggacccattctacacagagcaggactgcacagcgtcctgtccacacccagctcagcatttccacaccaagcagcaacag caaatcacgaccactgatagatgtctattcttgttggagacatgggatgattattttctgttctatttgtgcttagtcca attccttgcacatagtaggtacccaattcaattactattgaatgaattaagaattggttgccataaaaataaatcagttc atttaaaaaaaaaaaaaaaa (SEQ ID NO:12188) gggcccggcgctcgctgctcccgcggcccgcgccatgccctcctacacggtcaccgtggccactggcagccagtggttcg ccggcactgacgactacatctacctcagcctcgtgggctcggcgggctgcagcgagaagcacctgctggacaagcccttc tacaacgacttcgagcgtggcgcggtggattcatacgacgtgactgtggacgaggaactgggcgagatccagctggtcag aatcgagaagcgcaagtactggctgaatgacgactggtacctgaagtacatcacgctgaagacgccccacggggactaca tcgagttcccctgctaccgctggatcaccggcgatgtcgaggttgtcctgagggatggacgcgcaaagttggcccgagat gaccaaattcacattctcaagcaacaccgacgtaaagaactggaaacacggcaaaaacaatatcgatggatggagtggaa ccctggcttccccttgagcatcgatgccaaatgccacaaggatttaccccgtgatatccagtttgatagtgaaaaaggag tggactttgttctgaattactccaaagcgatggagaacctgttcatcaaccgcttcatgcacatgttccagtcttcttgg aatgacttcgccgactttgagaaaatctttgtcaagatcagcaacactatttctgagcgggtcatgaatcactggcagga agacctgatgtttggctaccagttcctgaatggctgcaaccctgtgttgatccggcgctgcacagagctgcccgagaagc tcccggtgaccacggagatggtagagtgcagcctggagcggcagctcagcttggagcaggaggtccagcaagggaacatt ttcatcgtggactttgagctgctggatggcatcgatgccaacaaaacagacccctgcacactccagttcctggccgctcc catctgcttgctgtataagaacctggccaacaagattgtccccattgccatccagctcaaccaaatcccgggagatgaga accctattttcctcccttcggatgcaaaatacgactggcttttggccaaaatctgggtgcgttccagtgacttccacgtc caccagaccatcacccaccttctgcgaacacatctggtgtctgaggtttttggcattgcaatgtaccgccagctgcctgc tgtgcaccccattttcaagctgctggtggcacacgtgagattcaccattgcaatcaacaccaaggcccgtgagcagctca tctgcgagtgtggcctctttgacaaggccaacgccacagggggcggtgggcacgtgcagatggtgcagagggccatgaag gacctgacctatgcctccctgtgctttcccgaggccatcaaggcccggggcatggagagcaaagaagacatcccctacta cttctaccgggacgacgggctcctggtgtgggaagccatcaggacgttcacggccgaggtggtagacatctactacgagg gcgaccaggtggtggaggaggacccggagctgcaggacttcgtgaacgatgtctacgtgtacggcatgcggggccgcaag tcctcaggcttccccaagtcggtcaagagccgggagcagctgtcggagtacctgaccgtggtgatcttcaccgcctccgc ccagcacgccgcggtcaacttcggccagtacgactggtgctcctggatccccaatgcgcccccaaccatgcgagccccgc caccgactgccaagggcgtggtgaccattgagcagatcgtggacacgctgcccgaccgcggccgctcctgctggcatctg ggtgcagtgtgggcgctgagccagttccaggaaaacgagctgttcctgggcatgtacccagaagagcattttatcgagaa gcctgtgaaggaagccatggcccgattccgcaagaacctcgaggccattgtcagcgtgattgctgagcgcaacaagaaga agcagctgccatattactacttgtccccagaccggattccgaacagtgtggccatctgagcacactgccagtctcactgt gggaaggccagctgccccagccagatggactccagcctgcctggcaggtgtctggccaggcctcttggcagtcacatctc ttcctccgaggccagtacctttccatttattctttgatcttcagggaactgcatagattgatcaaagtgtaaacaccata gggacccattctacacagagcaggactgcacagcgtcctgtccacacccagctcagcatttccacaccaagcagcaacag caaatcacgaccactgatagatgtctattcttgttggagacatgggatgattattttctgttctatttgtgcttagtcca attccttgcacatagtaggtacccaattcaattactattgaatgaattaagaattggttgccataaaaataaatcagttc attt (SEQ ID NO: 12189) gggcgccgaggctccccgccgctcgctgctccccggcccgcgccatgccctcctacacggtcaccgtggccactggcagc cagtggttcgccggcactgacgactacatctacctcagcctcgtgggctcggcgggctgcagcgagaagcacctgctgga caagcccttctacaacgacttcgagcgtggcgcggtggattcatacgacgtgactgtggacgaggaactgggcgagatcc agctggtcagaatcgagaagcgcaagtactggctgaatgacgactggtacctgaagtacatcacgctgaagacgccccac ggggactacatcgagttcccctgctaccgctggatcaccggcgatgtcgaggttgtcctgagggatggacgcgcaaagtt ggcccgagatgaccaaattcacattctcaagcaacaccgacgtaaagaactggaaacacggcaaaaacaatatcgatgga tggagtggaaccctggcttccccttgagcatcgatgccaaatgccacaaggatttaccccgtgatatccagtttgatagt gaaaaaggagtggactttgttctgaattactccaaagcgatggagaacctgttcatcaaccgcttcatgcacatgttcca gtcttcttggaatgacttcgccgactttgagaaaatctttgtcaagatcagcaacactatttctgagcgggtcatgaatc actggcaggaagacctgatgtttggctaccagttcctgaatggctgcaaccctgtgttgatccggcgctgcacagagctg cccgagaagctcccggtgaccacggagatggtagagtgcagcctggagcggcagctcagcttggagcaggaggtccagca agggaacattt catcgtggactttgagctgctggatggcatcgatgccaacaaaacagacccctgcacactccagttcc tggccgctcccatctgcttgctgtataagaacctggccaacaagattgtccccattgccatccagctcaaccaaatcccg ggagatgagaaccctattttcctcccttcggatgcaaaatacgactggcttttggccaaaatctgggtgcgttccagtga cttccacgtccaccagaccatcacccaccttctgcgaacacatctggtgtctgaggtttttggcattgcaatgtaccgcc agctgcctgctgtgcaccccattttcaagctgctggtggcacacgtgagattcaccattgcaatcaacaccaaggcccgt gagcagctcatctgcgagtgtggcctctttgacaaggccaacgccacagggggcggtgggcacgtgcagatggtgcagag ggccatgaaggacctgacctatgcctccctgtgctttcccgaggccatcaaggcccggggcatggagagcaaagaagaca tcccctactacttctaccgggacgacgggctcctggtgtgggaagccatcaggacgttcacggccgaggtggtagacatc tactacgagggcgaccaggtggtggaggaggacccggagctgcaggacttcgtgaacgatgtctacgtgtacggcatgcg gggccgcaagtcctcaggcttccccaagtcggtcaagagccgggagcagctgtcggagtacctgaccgtggtgatcttca ccgcctccgcccagcacgccgcggtcaacttcggccagtacgactggtgctcctggatccccaatgcgcccccaaccatg cgagccccgccaccgactgccaagggcgtggtgaccattgagcagatcgtggacacgctgcccgaccgcggccgctcctg ctggcatctgggtgcagtgtgggcgctgagccagttccaggaaaacgagctgttcctgggcatgtacccagaagagcatt ttatcgagaagcctgtgaaggaagccatggcccgattccgcaagaacctcgaggccattgtcagcgtgattgctgagcgc aacaagaagaagcagctgccatattactacttgtccccagaccggattccgaacagtgtggccatctgagcacactgcca gtctcactgtgggaaggccagctgccccagccagatggactccagcctgcctggcaggctgtctggccaggcctcttggc agtcacatctcttcctccgaggccagtacctttccatttattctttgatcttcagggaactgcatagattgtatcaaagt gtaaacaccatagggacccattctacacagagcaggactgcacaggcgtcctgtccacacccagctcagcatttccacac caagcagcaacagcaaatcacgaccactgatagatgtctattcttgttggagacatgggatgattattttctgttctatt tgtgcttagtccaattccttgcacatagtaggtacccaattcaattactattgaatgaattaagaattggttgccataaa aataaatcagttcattt (SEQ ID NO: 12190) cagctgtccctccccactgccatttattccttccttcattcaaaccttatgtggctgctacttaccgtgtgttaagt tt cactttttttcttggaattcaaaaaaagaaggacagtatttggggcacagatcttttggtgttctatacatttttttaaa gtttcattttacatttgtgtgtgcgtgtgtgtgtgtgtgtgagacagtcttgctctgttgcccaggctggagtgcagtgg cataatcattggctcactgtagcctcaaagtcctgggcccaagcgatcttcccacctcagccacccaaaatgctggggtt acaggtttatgccactctgtctgacctgaaagttttgggtttactttcccttctttctctttgctgaagtcagagatgat ggcagcttccagattctctggtgcctgtgctgggctcgtgctggtcatggtcttgggtccaggattcattctggagactc tcagggaagtttcccatgacaaggaaatgtaggagagtgtgctggctttgcgtgctcctctgccaagccctgcttctcct ggtgggacacactgaaccacagccagggcattttggtggttagttaaaaaaaaaaaaaaaaaaaaaaaggaagaagaagg cactgtgtaattgtgccggggatcttcagaaattgtaatgatgaaagagtgcaagctctcacttccccttcctgtacagg gcaggttgtgcagctggaggcagagcagtcctctctggggagcctgaagcaaacatggatcaagaaactgtaggcaatgt tgtcctgttggccatcgtcaccctcatcagcgtggtccagaatggtaaggaaagcccttcactcagggaagaacagaagg ggagattttctttgatggttgtttggaagtcaggcttaaacaattgtgtctgtgtgtgcgcatgcacaaacacttttacc ttatctttattttcttctttttatttgaatgtatagggttgtgtgtatttctgtgtaaatttggggttttcctcctctta gtctttcacttttgtggtgattaccagtcccatttttagagccagggctgcaacttgaaggttttgcttgcgttttgggg gttcctggagtatcaatctgcgttttgggggttcctggagtatcaatcatggatcaagaaactgtaggcaatgttgtcct gttggccatcgtcaccctcatcagcgtggtccagaatggattctttgcccataaagtggagcacgaaagcaggacccaga atgggaggagcttccagaggaccggaacacttgcctttgagcgggtctacactgccaaccagaactgtgtagatgcgtac cccactttcctcgctgtgctctggtctgcggggctactttgcagccaagttcctgctgcgtttgctggactgatgtactt gtttgtgcggcaaaagtactttgtcggttacctaggagagagaacgcagagcacccctggctacatatttgggaaacgca tcatactcttcctgttcctcatgtccgttgctggcatattcaactattacctcatcttctttttcggaagtgactttgaa aactacataaagacgatctccaccaccatctcccctctacttctcatttcctaactctctgctgaatatggggttggtat gccctcctacacggtcaccgtggccactggcagccagtggttcgccggcactgacgactacatctacctcagcctcgtgg gctcggcgggctgcagcgagaagcacctgctggacaagcccttctacaacgacttcgagcgtggcgcggtggattcatac gacgtgactgtggacgaggaactgggcgagatccagctggtcagaatcgagaagcgcaagtactggctgaatgacgactg gtacctgaagtacatcacgctgaagacgccccacggggactacatcgagttcccctgctaccgctggatcaccggcgatg tcgaggttgtcctgagggatggacgcgcaaagttggcccgagatgaccaaattcacattctcaagcaacaccgacgtaaa gaactggaaacacggcaaaaacaatatcgatggatggagtggaaccctggcttccccttgagcatcgatgccaaatgcca caaggatttaccccgtgatatccagtttgatagtgaaaaaggagtggactttgttctgaattactccaaagcgatggaga acctgttcatcaaccgcttcatgcacatgttccagtcttcttggaatgacttcgccgactttgagaaaatctttgtcaag atcagcaacactatttctgagcgggtcatgaatcactggcaggaagacctgatgtttggctaccagttcctgaatggctg caaccctgtgttgatccggcgctgcacagagctgcccgagaagctcccggtgaccacggagatggtagagtgcagcctgg agcggcagctcagcttggagcaggaggtccagcaagggaacattttcatcgtggactttgagctgctggatggcatcgat gccaacaaaacagacccctgcacactccagttcctggccgctcccatctgcttgctgtataagaacctggccaacaagat tgtccccattgccatccagctcaaccaaatcccgggagatgagaaccctattttcctcccttcggatgcaaaatacgact ggcttttggccaaaatctgggtgcgttccagtgacttccacgtccaccagaccatcacccaccttctgcgaacacatctg gtgtctgaggtttttggcattgcaatgtaccgccagctgcctgctgtgcaccccattttcaagctgctggtggcacacgt gagattcaccattgcaatcaacaccaaggcccgtgagcagctcatctgcgagtgtggcctctttgacaaggccaacgcca cagggggcggtgggcacgtgcagatggtgcagagggccatgaaggacctgacctatgcctccctgtgctttcccgaggcc atcaaggcccggggcatggagagcaaagaagacatcccctactacttctaccgggacgacgggctcctggtgtgggaagc catcaggacgttcacggccgaggtggtagacatctactacgagggcgaccaggtggtggaggaggacccggagctgcagg acttcgtgaacgatgtctacgtgtacggcatgcggggccgcaagtcctcaggcttccccaagtcggtcaagagccgggag cagctgtcggagtacctgaccgtggtgatcttcaccgcctccgcccagcacgccgcggtcaacttcggccagtacgactg gtgctcctggatccccaatgcgcccccaaccatgcgagccccgccaccgactgccaagggcgtggtgaccattgagcaga tcgtggacacgctgcccgaccgcggccgctcctgctggcatctgggtgcagtgtgggcgctgagccagttccaggaaaac gagctgttcctgggcatgtacccagaagagcattttatcgagaagcctgtgaaggaagccatggcccgattccgcaagaa cctcgaggccattgtcagcgtgattgctgagcgcaacaagaagaagcagctgccatattactacttgtccccagaccgga ttccgaacagtgtggccatcgggcccggcgctcgctgctcccgcggcccgcgccatgccctcctacacggtcaccgtggc cactggcagccagtggttcgccggcactgacgactacatctacctcagcctcgtgggctcggcgggctgcagcgagaagc acctgctggacaagcccttctacaacgacttcgagcgtggcgcggtggattcatacgacgtgactgtggacgaggaactg ggcgagatccagctggtcagaatcgagaagcgcaagtactggctgaatgacgactggtacctgaagtacatcacgctgaa gacgccccacggggactacatcgagttcccctgctaccgctggatcaccggcgatgtcgaggttgtcctgagggatggac gcgcaaagttggcccgagatgaccaaattcacattctcaagcaacaccgactgaaagaactggaaacacggcaaaaacaa tatcgatggatggagtggaaccctggcttccccttgagcatcgatgccaaatgccacaaggatttaccccgtgatatcca gtttgatagtgaaaaaggagtggactttgttctgaattactccaaagcgatggagaacctgttcatcaaccgcttcatgc acatgttccagtcttcttggaatgacttcgccgactttgagaaaatctttgtcaagatcagcaacactatttctgagcgg gtcatgaatcactggcaggaagacctgatgtttggctaccagttcctgaatggctgcaaccctgtgttgatccggcgctg cacagagctgcccgagaagctcccggtgaccacggagatggtagagtgcagcctggagcggcagctcagcttggagcagg aggtccagcaagggaacattttcatcgtggactttgagctgctggatggcatcgatgccaacaaaacagacccctgcaca ctccagttcctggccgctcccatctgcttgctgtataagaacctggccaacaagattgtccccattgccatccagctcaa ccaaatcccgggagatgagaaccctattttcctcccttcggatgcaaaatacgactggcttttggccaaaatctgggtgc gttccagtgacttccacgtccaccagaccatcacccaccttctgcgaacacatctggtgtctgaggtttttggcattgca atgtaccgccagctgcctgctgtgcaccccattttcaagctgctggtggcacacgtgagattcaccattgcaatcaacac caaggcccgtgagcagctcatctgcgagtgtggcctctttgacaaggccaacgccacagggggcggtgggcacgtgcaga tggtgcagagggccatgaaggacctgacctatgcctccctgtgctttcccgaggccatcaaggcccggggcatggagagc aaagaagacatcccctactacttctaccgggacgacgggctcctggtgtgggaagccatcaggacgttcacggccgaggt ggtagacatctactacgagggcgaccaggtggtggaggaggacccggagctgcaggacttcgtgaacgatgtctacgtgt acggcatgcggggccgcaagtcctcaggcttccccaagtcggtcaagagccgggagcagctgtcggagtacctgaccgtg gtgatcttcaccgcctccgcccagcacgccgcggtcaacttcggccagtacgactggtgctcctggatccccaatgcgcc cccaaccatgcgagccccgccaccgactgccaagggcgtggtgaccattgagcagatcgtggacacgctgcccgaccgcg gccgctcctgctggcatctgggtgcagtgtgggcgctgagccagttccaggaaaacgagctgttcctgggcatgtaccca gaagagcattttatcgagaagcctgtgaaggaagccatggcccgattccgcaagaacctcgaggccattgtcagcgtgat tgctgagcgcaacaagaagaagcagctgccatattactacttgtccccagaccggattccgaacagtgtggccatctgag cacactgccagtctcactgtgggaaggccagctgccccagccagatggactccagcctgcctggcaggtgtctggccagg cctcttggcagtcacatctcttcctccgaggccagtacctttccatttattctttgatcttcagggaactgcatagattg atcaaagtgtaaacaccatagggacccattctacacagagcaggactgcacagcgtcctgtccacacccagctcagcatt tccacaccaagcagcaacagcaaatcacgaccactgatagatgtctattcttgttggagacatgggatgattattttctg ttctatttgtgcttagtccaattccttgcacatagtaggtacccaattcaattactattgaatgaattaagaattggttg ccataaaaataaatcagttcatttaaaaaaaaaaaaaaaagggcccggcgctcgctgctcccgcggcccgcgccatgccc tcctacacggtcaccgtggccactggcagccagtggttcgccggcactgacgactacatctacctcagcctcgtgggctc ggcgggctgcagcgagaagcacctgctggacaagcccttctacaacgacttcgagcgtggcgcggtggattcatacgacg tgactgtggacgaggaactgggcgagatccagctggtcagaatcgagaagcgcaagtactggctgaatgacgactggtac ctgaagtacatcacgctgaagacgccccacggggactacatcgagttcccctgctaccgctggatcaccggcgatgtcga ggttgtcctgagggatggacgcgcaaagttggcccgagatgaccaaattcacattctcaagcaacaccgacgtaaagaac tggaaacacggcaaaaacaatatcgatggatggagtggaaccctggcttccccttgagcatcgatgccaaatgccacaag gatttaccccgtgatatccagtttgatagtgaaaaaggagtggactttgttctgaattactccaaagcgatggagaacct gttcatcaaccgcttcatgcacatgttccagtcttcttggaatgacttcgccgactttgagaaaatctttgtcaagatca gcaacactatttctgagcgggtcatgaatcactggcaggaagacctgatgtttggctaccagttcctgaatggctgcaac cctgtgttgatccggcgctgcacagagctgcccgagaagctcccggtgaccacggagatggtagagtgcagcctggagcg gcagctcagcttggagcaggaggtccagcaagggaacattttcatcgtggactttgagctgctggatggcatcgatgcca acaaaacagacccctgcacactccagttcctggccgctcccatctgcttgctgtataagaacctggccaacaagattgtc cccattgccatccagctcaaccaaatcccgggagatgagaaccctattttcctcccttcggatgcaaaatacgactggct tttggccaaaatctgggtgcgttccagtgacttccacgtccaccagaccatcacccaccttctgcgaacacatctggtgt ctgaggtttttggcattgcaatgtaccgccagctgcctgctgtgcaccccattttcaagctgctggtggcacacgtgaga ttcaccattgcaatcaacaccaaggcccgtgagcagctcatctgcgagtgtggcctctttgacaaggccaacgccacagg gggcggtgggcacgtgcagatggtgcagagggccatgaaggacctgacctatgcctccctgtgctttcccgaggccatca aggcccggggcatggagagcaaagaagacatcccctactacttctaccgggacgacgggctcctggtgtgggaagccatc aggacgttcacggccgaggtggtagacatctactacgagggcgaccaggtggtggaggaggacccggagctgcaggactt cgtgaacgatgtctacgtgtacggcatgcggggccgcaagtcctcaggcttccccaagtcggtcaagagccgggagcagc tgtcggagtacctgaccgtggtgatcttcaccgcctccgcccagcacgccgcggtcaacttcggccagtacgactggtgc tcctggatccccaatgcgcccccaaccatgcgagccccgccaccgactgccaagggcgtggtgaccattgagcagatcgt ggacacgctgcccgaccgcggccgctcctgctggcatctgggtgcagtgtgggcgctgagccagttccaggaaaacgagc tgttcctgggcatgtacccagaagagcattttatcgagaagcctgtgaaggaagccatggcccgattccgcaagaacctc gaggccattgtcagcgtgattgctgagcgcaacaagaagaagcagctgccatattactacttgtccccagaccggattcc gaacagtgtggccatctgagcacactgccagtctcactgtgggaaggccagctgccccagccagatggactccagcctgc ctggcaggtgtctggccaggcctcttggcagtcacatctcttcctccgaggccagtacctttccatttattctttgatct tcagggaactgcatagattgatcaaagtgtaaacaccatagggacccattctacacagagcaggactgcacagcgtcctg tccacacccagctcagcatttccacaccaagcagcaacagcaaatcacgaccactgatagatgtctattcttgttggaga catgggatgattattttctgttctatttgtgcttagtccaattccttgcacatagtaggtacccaattcaattactattg aatgaattaagaattggttgccataaaaataaatcagttcatttgggcgccgaggctccccgccgctcgctgctccccgg cccgcgccatgccctcctacacggtcaccgtggccactggcagccagtggttcgccggcactgacgactacatctacctc agcctcgtgggctcggcgggctgcagcgagaagcacctgctggacaagcccttctacaacgacttcgagcgtggcgcggt ggattcatacgacgtgactgtggacgaggaactgggcgagatccagctggtcagaatcgagaagcgcaagtactggctga atgacgactggtacctgaagtacatcacgctgaagacgccccacggggactacatcgagttcccctgctaccgctggatc accggcgatgtcgaggttgtcctgagggatggacgcgcaaagttggcccgagatgaccaaattcacattctcaagcaaca ccgacgtaaagaactggaaacacggcaaaaacaatatcgatggatggagtggaaccctggcttccccttgagcatcgatg ccaaatgccacaaggatttaccccgtgatatccagtttgatagtgaaaaaggagtggactttgttctgaattactccaaa gcgatggagaacctgttcatcaaccgcttcatgcacatgttccagtcttcttggaatgacttcgccgactttgagaaaat ctttgtcaagatcagcaacactatttctgagcgggtcatgaatcactggcaggaagacctgatgtttggctaccagttcc tgaatggctgcaaccctgtgttgatccggcgctgcacagagctgcccgagaagctcccggtgaccacggagatggtagag tgcagcctggagcggcagctcagcttggagcaggaggtccagcaagggaacattttcatcgtggactttgagctgctgga tggcatcgatgccaacaaaacagacccctgcacactccagttcctggccgctcccatctgcttgctgtataagaacctgg ccaacaagattgtccccattgccatccagctcaaccaaatcccgggagatgagaaccctattttcctcccttcggatgca aaatacgactggcttttggccaaaatctgggtgcgttccagtgacttccacgtccaccagaccatcacccaccttctgcg aacacatctggtgtctgaggtttttggcattgcaatgtaccgccagctgcctgctgtgcaccccattttcaagctgctgg tggcacacgtgagattcaccattgcaatcaacaccaaggcccgtgagcagctcatctgcgagtgtggcctctttgacaag gccaacgccacagggggcggtgggcacgtgcagatggtgcagagggccatgaaggacctgacctatgcctccctgtgctt tcccgaggccatcaaggcccggggcatggagagcaaagaagacatcccctactacttctaccgggacgacgggctcctgg tgtgggaagccatcaggacgttcacggccgaggtggtagacatctactacgagggcgaccaggtggtggaggaggacccg gagctgcaggacttcgtgaacgatgtctacgtgtacggcatgcggggccgcaagtcctcaggcttccccaagtcggtcaa gagccgggagcagctgtcggagtacctgaccgtggtgatcttcaccgcctccgcccagcacgccgcggtcaacttcggcc agtacgactggtgctcctggatccccaatgcgcccccaaccatgcgagccccgccaccgactgccaagggcgtggtgacc attgagcagatcgtggacacgctgcccgaccgcggccgctcctgctggcatctgggtgcagtgtgggcgctgagccagtt ccaggaaaacgagctgttcctgggcatgtacccagaagagcattttatcgagaagcctgtgaaggaagccatggcccgat tccgcaagaacctcgaggccattgtcagcgtgattgctgagcgcaacaagaagaagcagctgccatattactacttgtcc ccagaccggattccgaacagtgtggccatctgagcacactgccagtctcactgtgggaaggccagctgccccagccagat ggactccagcctgcctggcaggctgtctggccaggcctcttggcagtcacatctcttcctccgaggccagtacctttcca tttattctttgatcttcagggaactgcatagattgtatcaaagtgtaaacaccatagggacccattctacacagagcagg actgcacaggcgtcctgtccacacccagctcagcatttccacaccaagcagcaacagcaaatcacgaccactgatagatg tctattcttgttggagacatgggatgattattttctgttctatttgtgcttagtccaattccttgcacatagtaggtacc caattcaattactattgaatgaattaagaattggttgccataaaaataaatcagttcattt (SEQ ID NO: 12191) ggcacgaggctggctgagccatgatgctgctgccagaacccctgcagagggcctggtttcaggagactcagagtcctctg tgaaaaagcccttggagaggcgccccagcagggctgcacttggctcctgtgaggaaggggctcagggtctgggcccctcc gcctgggccgggctgggagccaggcgggcggctgggctgcagcaatggaccgtgagctggcccagcccgcgtccgtgctg agcctgcctgtcgtctgtggccatgccatcatgggctcctcggtgtacatcacggtggagctggccattgctgtgctggc catcctgggcaatgtgctggtgtgctgggccgtgtggctcaacagcaacctgcagaacgtcaccaactactttgtggtgt cactggcggcggccgacatcgcagtgggtgtgctcgccatcccctttgccatcaccatcagcaccgggttctgcgctgcc tgccacggctgcctcttcattgcctgcttcgtcctggtcctcacgcagagctccatcttcagtctcctggccatcgccat tgaccgctacattgccatccgcatcccgctccggtacaatggcttggtgaccggcacgagggctaagggcatcattgcca tctgctgggtgctgtcgtttgccatcggcctgactcccatgctaggttggaacaactgcggtcagccaaaggagggcaag aaccactcccagggctgcggggagggccaagtggcctgtctctttgaggatgtggtccccatgaactacatggtgtactt caacttctttgcctgtgtgctggtgcccctgctgctcatgctgggtgtctatttgcggatcttcctggcggcgcgacgac agctgaagcagatggagagccagcctctgccgggggagcgggcacggtccacactgcagaaggaggtccatgctgccaag tcactggccatcattgtggggctctttgccctctgctggctgcccctacacatcatcaactgcttcactttcttctgccc cgactgcagccacgcccctctctggctcatgtacctggccatcgtcctctcccacaccaattcggttgtgaatcccttca tctacgcctaccgtatccgcgagttccgccagaccttccgcaagatcattcgcagccacgtcctgaggcagcaagaacct ttcaaggcagctggcaccagtgcccgggtcttggcagctcatggcagtgacggagagcaggtcagcctccgtctcaacgg ccacccgccaggagtgtgggccaacggcagtgctccccaccctgagcggaggcccaatggctatgccctggggctggtga gtggagggagtgcccaagagtcccaggggaacacgggcctcccagacgtggagctccttagccatgagctcaagggagtg tgcccagagccccctggcctagatgaccccctggcccaggatggagcaggagtgtcctgatgattcatggagtttgcccc ttcctaagggaaggagatctttatctttctggttggcttgaccagtcacgttgggagaagagagagagtgccaggagacc ctgagggcagccggttcctactttggactgagagaagggagccccaggctggagcagcatgaggcccagcaagaagggct tgggttctgaggaagcagatgtttcatgctgtgaggccttgcaccaggtgggggccacagcaccagcagcatctttgctg ggcagggcccagccctccactgcagaagcatctggaagcaccaccttgtctccacagagcagcttgggcacagcagactg gcctggccctgagactggggagtggctccaacagcctcctgccacccacacaccactctccctagactctcctagggttc aggagctgctgggcccagaggtgacatttgacttttttccaggaaaaatgtaagtgtgaggaaaccctttttattttatt acctttcactctctggctgctgggtctgccgtcggtcctgctgctaacctggcaccagagcctctgccggggagcctcag gcagtcctctcctgctgtcacagctgccatccacttctcagtcccagggccatctcttggagtgacaaagctgggatcaa ggacagggagttgtaacagagcagtgccagagcatgggcccaggtcccaggggagaggttggggctggcaggccactggc atgtgctgagtagcgcagagctacccagtgagaggccttgtctaactgcctttccttctaaagggaatgtttttttctga gataaaataaaaacgagccacatcgtgttttaagcttgtccaaatgaaaaaaaaaaaaaaaaa (SEQ ID NO: 12192) catcacctttttttaagtagtaagaataaagccactgtatgattctcttaatagctatacattaatcctgtttttagtgc tgactgggccagccttccgggaactggagtctgtctctttcagtgcttttttgttttttgttggttttttcgagacgggg tcgatcacggctcaccacagccttaacctccagggctccagcaatcctcccacctcagcctcctgagtagctgggaccac aggtgtgtgccaccatctccagcagtttgtttatttattttttctttttttttttttggtagaaatgggcttttcgccca tgttgcccaagctggtcttgcacttctgggctgaagcaatcctctcgccttggcctcccagagccttgggattacagaat catgggtgagagctggcatggcccctagaggtcatttggggtccagctgcctcaccgtatcaatgaggaaactgaggccc agaaaagaaaagcatttttgcccagagtccctcagaaaaaaacagaccacatctgatccttggccctgagtccagagtgg gaggcaccgtgacaacaatgcgcagagcagggaatgcagggagccatggatagtgctggggtgcctcaggaaccctgaag ctgggctgagccatgatgctgctgccagaacccctgcagagggcctggtttcaggagactcagagtcctctgtgaaaaag cccttggagagcgccccagcagggctgcacttggctcctgtgaggaaggggctcaggggtctgggcccctccgcctgggc cgggctgggagccaggcgggcggctgggctgcagcaatggaccgtgagctggcccagcccgcgtccgtgctgagcctgcc tgtcgtctgtggcatgcccatcatgggctcctcggtgtacatcacggtggagctggccattgctgtgctggccatcctgg gcaatgtgctggtgtgctgggccgtgtggctcaacagcaacctgcagaacgtcaccaactactttgtggtgtcactggcg gcggccgacatcgcagtgggtgtgctcgccatcccctttgccatcaccatcagcaccgggttctgcgctgcctgccacgg ctgcctcttcattgcctgcttcgtcctggtcctcacgcagagctccatcttcagtctcctggccatcgccattgaccgct acattgccatccgcatcccgctccggtacaatggcttggtgaccggcacgagggctaagggcatcattgccatctgctgg gtgctgtcgtttgccatcggcctgactcccatgctaggttggaacaactgcggtcagccaaaggagggcaagaaccactc ccagggctgcggggagggccaagtggcctgtctctttgaggatgtggtccccatgaactacatggtgtacttcaacttct ttgcctgtgtgctggtgcccctgctgctcatgctgggtgtctatttgcggatcttcctggcggcgcgacgacagctgaag cagatggagagccagcctctgccgggggagcgggcacggtccacactgcagaaggaggtccatgctgccaagtcactggc catcattgtggggctctttgccctctgctggctgcccctacacatcatcaactgcttcactttcttctgccccgactgca gccacgcccctctctggctcatgtacctggccatcgtcctctcccacaccaattcggttgtgaatcccttcatctacgcc taccgtatccgcgagttccgccagaccttccgcaagatcattcgcagccacgtcctgaggcagcaagaacctttcaaggc agctggcaccagtgcccgggtcttggcagctcatggcagtgacggagagcaggtcagcctccgtctcaacggccacccgc caggagtgtgggccaacggcagtgctccccaccctgagcggaggcccaatggctatgccctggggctggtgagtggaggg agtgcccaagagtcccaggggaacacgggcctcccagacgtggagctccttagccatgagctcaagggagtgtgcccaga gccccctggcctagatgaccccctggcccaggatggagcaggagtgtcctgatgattcatggagtttgccccttcctaag ggaaggagatctttatctttctggttggcttgaccagtcacgttgggagaagagagagagtgccaggagaccctgagggc agccggttcctactttggactgagagaagggagccccaggctggagcagcatgaggcccagcaagaagggcttgggttct gaggaagcagatgtttcatgctgtgaggccttgcaccaggtgggggccacagcaccagcagcagcatctttctgggcagg cccagccctccactgcagaagcatctggaagcaccaccttgtctccacagagcagcttgggcacagcagactggcctggc cctgagactggggagtggctccaacagcctcctgccacccacacaccactctccctagactctcctagggttcaggagct gctgggcccagaggtgacatttgacttttttccaggaaaaatgtaagtgtgaggaaaccccttttattttattacctttc actctctggctgctgggtctgccgtcggtcctgctgctaacctggcagcagagcctctgcccggggagcctcaggcagtc ctctcctgctgtcacagctgccatccacttctcagtcccagggccatctcttggagtgacaaagctgggatcaaggacag ggagttgtaacagagcagtgccagagcatgggcccaggtcccaggggagaggttggggctggcaggccactggcatgtgc tgagtagcgcagagctacccagtgagaggccttgtctaactgcctttccttctaaagggaatgtttttttctgagataaa ataaaaacgagccacatcgtgttttaag (SEQ ID NO: 12193) ggcacgagcccagaaacaaagacttcacggacaaagtcccttggaaccagagagaagccgggatggaaactccaaacacc acagaggactatgacacgaccacagagtttgactatggggatgcaactccgtgccagaaggtgaacgagagggcctttgg ggcccaactgctgccccctctgtactccttggtatttgtcattggcctggttggaaacatcctggtggtcctggtccttg tgcaatacaagaggctaaaaaacatgaccagcatctacctcctgaacctggccatttctgacctgctcttcctgttcacg cttcccttctggatcgactacaagttgaaggatgactgggtttttggtgatgccatgtgtaagatcctctctgggtttta ttacacaggcttgtacagcgagatctttttcatcatcctgctgacgattgacaggtacctggccatcgtccacgccgtgt ttgccttgcgggcacggaccgtcacttttggtgtcatcaccagcatcatcatttgggccctggccatcttggcttccatg ccaggcttatacttttccaagacccaatgggaattcactcaccacacctgcagccttcactttcctcacgaaagcctacg agagtggaagctgtttcaggctctgaaactgaacctctttgggctggtattgcctttgttggtcatgatcatctgctaca cagggattataaagattctgctaagacgaccaaatgagaagaaatccaaagctgtccgtttgatttttgtcatcatgatc atcttttttctcttttggaccccctacaatttgactatacttatttctgttttccaagacttcctgttcacccatgagtg tgagcagagcagacatttggacctggctgtgcaagtgacggaggtgatcgcctacacgcactgctgtgtcaacccagtga tctacgccttcgttggtgagaggttccggaagtacctgcggcagttgttccacaggcgtgtggctgtgcacctggttaaa tggctccccttcctctccgtggacaggctggagagggtcagctccacatctccctccacaggggagcatgaactctctgc tgggttctgactcagaccataggaggccaacccaaaataagcaggcgtgacctgccaggcacactgagccagcagcctgg ctctcccagccaggttctgactcttggcacagcatggagtcacagccacttgggatagagagggaatgtaatggtggcct ggggcttctgaggcttctggggcttcagtcttttccatgaacttctcccctggtagaaagaagatgaatgagcaaaacca aatattccagagactgggactaagtgtaccagagaagggcttggactcaagcaagatttcagatttgtgaccattagcat ttgtcaacaaagtcacccacttcccactattgcttgcacaaaccaattaaacccagtagtggtgactgtgggctccattc aaagtgagctcctaagccatgggagacactgatgtatgaggaatttctgttcttccatcacctccccccccccgccaccc tcccactgccaagaacttggaaatagtgatttccacagtgactccactctgagtcccagagccaatcagtagccagcatc tgcctccccttcactcccaccgcaggatttgggctcttggaatcctggggaacatagaactcatgacggaagagttgaga cctaacgagaaatagaaatgggggaactactgctggcagtggaactaagaaagcccttaggaagaatttttatatccact aaaatcaaacaattcagggagtgggctaagcacgggccatatgaataacatggtgtgcttcttaaaatagccataaaggg gagggactcatcatttccatttacccttcttttctgactatttttcagaatctctcttcttttcaagttgggtgatatgt tggtagattctaatggctttattgcagcgattaataacaggcaaaaggaagcagggttggtttcccttctttttgttctt catctaagccttctggttttatgggtcagagttccgactgccatcttggacttgtcagcaaaaaaaaaaaaaaaaa (SEQ ID NO: 12194) agaagcttttgctcctgggattaggttgatgggcctctaatgtcaccagtgaaatgggatattagatattttccagctag gatacgacagctcccaataaaaccaaattactaagccttttctgcaagcaaggagccgtctggaacataaggactttaac cttgggtaggagacaggcaagcagaagtcttcaattgtgtcacaattttcactgaggactcaagtgacctaagaaagtaa ttgtgattgtcagagccttgttcttccttttctttctccagccgcacgcttcacctactcaggagagtgcctacgcaatc tgacttgacagcttctagaaagaaattagagcaacaggggtctcagcagggtggtcttgggccaaacactgaaagcaggc aggcttaccctttcctcttctgcccccttcaactttttcctgatgttcttacccacatccctcaccacaccacacccttt cattcatccttgtcccagacttattaagtatatacagataagcaatccagggaacttgcattcattaggagaaacccaga aattcaaaagcaataatgatctaatcccagaggagtagaaaacaggaagtgggcagctgccagctttcttgctttgctgg agtattctggaatttgatgggttgagggttctggacacaatgccccaagccccttccttgttgtgctgggttcctatttc tgctctcggcactgacttagcagctgctcaagagctcactatgttggcttggattacactggtctcacccacatctccgg cagtttgtgggcaaacctcctgagcagccttgggtgatgaaacctttcatggtagcaggagaatgggactgtgaattctc aatcccctgtccccaccccttccttcctctctcagggccttaaagtctaggaggaggaagcacagcagc (SEQ ID NO: 12195) cttgctttgctggagtattctggtaatttgatgggttgagggttctggacacaatgccccaagccccttccttgttgtgc tgggttcctatttctgctctcggcactgacttagcagctgctcaagagctcactatgttggcttggattacacggtctca cccacatctccggcagtttgtgggcaaacctcctgagcagccttgggtgatgaaacctttcatggtagcaggagaatggg actgtgaattctcaatcccctgtccccaccccttccttcctctctcagggccttaaagtctaggaggaggaagcacagca gcaactgactgggcagcctttcaggaaagatgcagccactcctgcttctgctggcctttctcctacccactggggctgag gcaggtgagtgaccatccccaccctcagaggcctgacctcatcccatagattcttgagccaaattgccttggtatatcct aattctgtactgttgagcaagttatttgaatttgtgtttcctcatctataaaatgagaataatattaataccgatcttgc agagttgccatgagagttaaataagttagagtatttaaatgtcttggaattgcccgcacactataagtgctataaaaaca tgctttgtgtaaataatttggcagcatgtgtcagaccctacctaggaggtaagaatacagcaataacagtaccatcagct catgtctagatttttaaacaccagtcccacgtggtcttgaattggactcagagggctctgggaagctccatgaggataaa agtataagggaacttcaggaacaatcctgtacttacagcaaagcattctcctcaatacctgaggctgaagctggccttgc ctggaacaagggttgttctccctcttttggagaggaggagggaggtgaggcctaggatggggaaaagggctcctttcaag acagcagtgtttcctgtagaaccctggagccccctcccaatctgctgccccatagactccaagcctcagcaccatctcct ccctctcctgcaccctctctcctgccgtccccatcttccagcctttctggagccaccaatctggtacccacattgcaggt tcagcaagcatagagctaagtgccaaatgcttccttccaggggagatcatcggaggccgggagagcaggccccactcccg cccctacatggcgtatcttcagatccagagtccagcaggtcagagcagatgtggagggttcctggtgcgagaagactttg tgctgacagcagctcattgctggggaaggtgaggagctaaggaacttcctggccagccaggaacacagccctgcggagct cttcggtggaagagccatctgaaagaagagttgtagcaatgaaagggtgaaagaaagaccaagtgagtctttgcgggagg gaacaggccagtgtaaatgaggaggaaaggaggataagatcaaaaagagcaagaggaagagatggaagacacatattggg gctcaaaatataaactcaggctatttatcaacttaatctggggaagtaaacctgaaggcaagtaccaccctgtcatccct agctcagagctgctgagaaagaggatacagctgagccccagggccctcccatcccctcgattctggttagctgcagtctt gccctccccgtgctgtctgcctaccctgcagagctggtggaccatagctcctgcagcccagacctacctcttgcttttgc agcaatataaatgtcaccctgggcgcccacaatatccagagacgggaaaacacccagcaacacatcactgcgcgcagagc catccgccaccctcaatataatcagcggaccatccagaatgacatcatgttattgcaggtaccacctacctggccctctg gctccttcctagtgtgtccggggacaatggaggaggaagtgagggcaaggctccggggtggcggggagggcatgggatgt gtactgcaccagcgacccccgagccttggctggaggccccagctgagcgggaacgcctacattcttcctccagctgagca gaagagtcagacggaatcgaaacgtgaacccagtggctctgcctagagcccaggagggactgagacccgggacgctgtgc actgtggccggctggggcagggtcagcatgaggaggggaacagatacactccgagaggtgcagctgagagtgcagaggga taggcagtgcctccgcatcttcggttcctacgacccccgaaggcagatttgtgtgggggaccggcgggaacggaaggctg_', ccttcaaggtaaggcatgggcattggccaacacaccccgggagagaggggcccgtgcagagccaggcagtgcgaacagat tccatccccacagcctcagcctggcagccagaccagggtgggctggggattgttttccccatcaacctggtctctggggg aataggaggaagacccacaacacatacataggcaacattctcctggagaagggagaggtaccttgactcagattgggctg gagacagtaattaaggcagagctgaagtccagcgaccgaaaagatccagaggcttggctcctgtaccccaccgatcttcc atctcacacacacccagcaattgaaggggcccacccacccctgccttccctgagagcccggagctcagggaagcaggagc agggaggcctgtctcagtctcccttctcctctctacctacagggggattccggaggccccctgctgtgtaacaatgtggc ccacggcatcgtctcctatggaaagtcgtcaggggttcctccagaagtcttcaccagggtctcaagtttcctgccctgga taaggacaacaatgagaagcttcaaactgctggatcagatggagacccccctgtgactgactcttcttctcggggacaca ggccagctccacagtgttgccagagccttaataaacgtccacagagtataaataaccaattcctcatttgttcattaaac gtcattcagtacttagtttgtttggattgctacaacaaaatagcacaaattgggtggcttataaataacaaatttatttc tcacaggtctagaggctaagaagtctaagatcaagtcactagcagattcagtgtctaattagggcccattttctggttca cagacaaccatcctctccctgtgtccacatatggcaaaaggggcaagggaattctctgatgtctcttttacaagggacct agtctcattcaaagagctcagcttttacgacctaatcacatcccaaaggccccacctaatgccatcacgacattggggat taggtctgggaaacatagggaaagagtgtctctacacaaaaattttaaaattagccaggcatggtggcatgtgtctatag tcccagctacttgggaggctaaagtggaaggattagttgaacccacgaggttgaggcttcagtgaaccatgcactccagc ctgagcgacagagcaagacaccattccaagaaagaaaaaaaaaaagactggcaggccaaaaagacagaactgaaattcca aaaaaaaagacctactttagtgtatgaaaaaggtggcatctcaaatcactgggaaacaatggaatttttgaataaatagc attagaaccaacctagatagatatttggaggggatggaaggtataattggatcc (SEQ ID NO: 12196) agaagcttttgctcctgggattaggttgatgggcctctaatgtcaccagtgaaatgggatattagatattttccagctag gatacgacagctcccaataaaaccaaattactaagccttttctgcaagcaaggagccgtctggaacataaggactttaac cttgggtaggagacaggcaagcagaagtcttcaattgtgtcacaattttcactgaggactcaagtgacctaagaaagtaa ttgtgattgtcagagccttgttcttccttttctttctccagccgcacgcttcacctactcaggagagtgcctacgcaatc tgacttgacagcttctagaaagaaattagagcaacaggggtctcagcagggtggtcttgggccaaacactgaaagcaggc aggcttaccctttcctcttctgcccccttcaactttttcctgatgttcttacccacatccctcaccacaccacacccttt cattcatccttgtcccagacttattaagtatatacagataagcaatccagggaacttgcattcattaggagaaacccaga aattcaaaagcaataatgatctaatcccagaggagtagaaaacaggaagtgggcagctgccagctttcttgctttgctgg agtattctggaatttgatgggttgagggttctggacacaatgccccaagccccttccttgttgtgctgggttcctatttc tgctctcggcactgacttagcagctgctcaagagctcactatgttggcttggattacactggtctcacccacatctccgg cagtttgtgggcaaacctcctgagcagccttgggtgatgaaacctttcatggtagcaggagaatgggactgtgaattctc aatcccctgtccccaccccttccttcctctctcagggccttaaagtctaggaggaggaagcacagcagccttgctttgct ggagtattctggtaatttgatgggttgagggttctggacacaatgccccaagccccttccttgttgtgctgggttcctat ttctgctctcggcactgacttagcagctgctcaagagctcactatgttggcttggattacacggtctcacccacatctcc ggcagtttgtgggcaaacctcctgagcagccttgggtgatgaaacctttcatggtagcaggagaatgggactgtgaattc tcaatcccctgtccccaccccttccttcctctctcagggccttaaagtctaggaggaggaagcacagcagcaactgactg ggcagcctttcaggaaagatgcagccactcctgcttctgctggcctttctcctacccactggggctgaggcaggtgagtg accatccccaccctcagaggcctgacctcatcccatagattcttgagccaaattgccttggtatatcctaattctgtact gttgagcaagttatttgaatttgtgtttcctcatctataaaatgagaataatattaataccgatcttgcagagttgccat gagagttaaataagttagagtatttaaatgtcttggaattgcccgcacactataagtgctataaaaacatgctttgtgta aataatttggcagcatgtgtcagaccctacctaggaggtaagaatacagcaataacagtaccatcagctcatgtctagat ttttaaacaccagtcccacgtggtcttgaattggactcagagggctctgggaagctccatgaggataaaagtataaggga acttcaggaacaatcctgtacttacagcaaagcattctcctcaatacctgaggctgaagctggccttgcctggaacaagg gttgttctccctcttttggagaggaggagggaggtgaggcctaggatggggaaaagggctcctttcaagacagcagtgtt tcctgtagaaccctggagccccctcccaatctgctgccccatagactccaagcctcagcaccatctcctccctctcctgc accctctctcctgccgtccccatcttccagcctttctggagccaccaatctggtacccacattgcaggttcagcaagcat agagctaagtgccaaatgcttccttccaggggagatcatcggaggccgggagagcaggccccactcccgcccctacatgg cgtatcttcagatccagagtccagcaggtcagagcagatgtggagggttcctggtgcgagaagactttgtgctgacagca gctcattgctggggaaggtgaggagctaaggaacttcctggccagccaggaacacagccctgcggagctcttcggtggaa gagccatctgaaagaagagttgtagcaatgaaagggtgaaagaaagaccaagtgagtctttgcgggagggaacaggccag tgtaaatgaggaggaaaggaggataagatcaaaaagagcaagaggaagagatggaagacacatattggggctcaaaatat aaactcaggctatttatcaacttaatctggggaagtaaacctgaaggcaagtaccaccctgtcatccctagctcagagct gctgagaaagaggatacagctgagccccagggccctcccatcccctcgattctggttagctgcagtcttgccctccccgt gctgtctgcctaccctgcagagctggtggaccatagctcctgcagcccagacctacctcttgcttttgcagcaatataaa tgtcaccctgggcgcccacaatatccagagacgggaaaacacccagcaacacatcactgcgcgcagagccatccgccacc ctcaatataatcagcggaccatccagaatgacatcatgttattgcaggtaccacctacctggccctctggctccttccta gtgtgtccggggacaatggaggaggaagtgagggcaaggctccggggtggcggggagggcatgggatgtgtactgcacca gcgacccccgagccttggctggaggccccagctgagcgggaacgcctacattcttcctccagctgagcagaagagtcaga cggaatcgaaacgtgaacccagtggctctgcctagagcccaggagggactgagacccgggacgctgtgcactgtggccgg ctggggcagggtcagcatgaggaggggaacagatacactccgagaggtgcagctgagagtgcagagggataggcagtgcc tccgcatcttcggttcctacgacccccgaaggcagatttgtgtgggggaccggcgggaacggaaggctgccttcaaggta aggcatgggcattggccaacacaccccgggagagaggggcccgtgcagagccaggcagtgcgaacagattccatccccac agcctcagcctggcagccagaccagggtgggctggggattgttttccccatcaacctggtctctgggggaataggaggaa gacccacaacacatacataggcaacattctcctggagaagggagaggtaccttgactcagattgggctggagacagtaat taaggcagagctgaagtccagcgaccgaaaagatccagaggcttggctcctgtaccccaccgatcttccatctcacacac acccagcaattgaaggggcccacccacccctgccttccctgagagcccggagctcagggaagcaggagcagggaggcctg tctcagtctcccttctcctctctacctacagggggattccggaggccccctgctgtgtaacaatgtggcccacggcatcg tctcctatggaaagtcgtcaggggttcctccagaagtcttcaccagggtctcaagtttcctgccctggataaggacaaca atgagaagcttcaaactgctggatcagatggagacccccctgtgactgactcttcttctcggggacacaggccagctcca cagtgttgccagagccttaataaacgtccacagagtataaataaccaattcctcatttgttcattaaacgtcattcagta cttagtttgtttggattgctacaacaaaatagcacaaattgggtggcttataaataacaaatttatttctcacaggtcta gaggctaagaagtctaagatcaagtcactagcagattcagtgtctaattagggcccattttctggttcacagacaaccat cctctccctgtgtccacatatggcaaaaggggcaagggaattctctgatgtctcttttacaagggacctagtctcattca aagagctcagcttttacgacctaatcacatcccaaaggccccacctaatgccatcacgacattggggattaggtctggga aacatagggaaagagtgtctctacacaaaaattttaaaattagccaggcatggtggcatgtgtctatagtcccagctact tgggaggctaaagtggaaggattagttgaacccacgaggttgaggcttcagtgaaccatgcactccagcctgagcgacag agcaagacaccattccaagaaagaaaaaaaaaaagactggcaggccaaaaagacagaactgaaattccaaaaaaaaagac ctactttagtgtatgaaaaaggtggcatctcaaatcactgggaaacaatggaatttttgaataaatagcattagaaccaa cctagatagatatttggaggggatggaaggtataattggatcc (SEQ ID NO: 12197) ggcacgagcccagaaacaaagacttcacggacaaagtcccttggaaccagagagaagccgggatggaaactccaaacacc acagaggactatgacacgaccacagagtttgactatggggatgcaactccgtgccagaaggtgaacgagagggcctttgg ggcccaactgctgccccctctgtactccttggtatttgtcattggcctggttggaaacatcctggtggtcctggtccttg tgcaatacaagaggctaaaaaacatgaccagcatctacctcctgaacctggccatttctgacctgctcttcctgttcacg cttcccttctggatcgactacaagttgaaggatgactgggtttttggtgatgccatgtgtaagatcctctctgggtttta ttacacaggcttgtacagcgagatctttttcatcatcctgctgacgattgacaggtacctggccatcgtccacgccgtgt ttgccttgcgggcacggaccgtcacttttggtgtcatcaccagcatcatcatttgggccctggccatcttggcttccatg ccaggcttatacttttccaagacccaatgggaattcactcaccacacctgcagccttcactttcctcacgaaagcctacg agagtggaagctgtttcaggctctgaaactgaacctctttgggctggtattgcctttgttggtcatgatcatctgctaca cagggattataaagattctgctaagacgaccaaatgagaagaaatccaaagctgtccgtttgatttttgtcatcatgatc atcttttttctcttttggaccccctacaatttgactatacttatttctgttttccaagacttcctgttcacccatgagtg tgagcagagcagacatttggacctggctgtgcaagtgacggaggtgatcgcctacacgcactgctgtgtcaacccagtga tctacgccttcgttggtgagaggttccggaagtacctgcggcagttgttccacaggcgtgtggctgtgcacctggttaaa tggctccccttcctctccgtggacaggctggagagggtcagctccacatctccctccacaggggagcatgaactctctgc tgggttctgactcagaccataggaggccaacccaaaataagcaggcgtgacctgccaggcacactgagccagcagcctgg ctctcccagccaggttctgactcttggcacagcatggagtcacagccacttgggatagagagggaatgtaatggtggcct ggggcttctgaggcttctggggcttcagtcttttccatgaacttctcccctggtagaaagaagatgaatgagcaaaacca aatattccagagactgggactaagtgtaccagagaagggcttggactcaagcaagatttcagatttgtgaccattagcat ttgtcaacaaagtcacccacttcccactattgcttgcacaaaccaattaaacccagtagtggtgactgtgggctccattc aaagtgagctcctaagccatgggagacactgatgtatgaggaatttctgttcttccatcacctccccccccccgccaccc tcccactgccaagaacttggaaatagtgatttccacagtgactccactctgagtcccagagccaatcagtagccagcatc tgcctccccttcactcccaccgcaggatttgggctcttggaatcctggggaacatagaactcatgacggaagagttgaga cctaacgagaaatagaaatgggggaactactgctggcagtggaactaagaaagcccttaggaagaatttttatatccact aaaatcaaacaattcagggagtgggctaagcacgggccatatgaataacatggtgtgcttcttaaaatagccataaaggg gagggactcatcatttccatttacccttcttttctgactatttttcagaatctctcttcttttcaagttgggtgatatgt tggtagattctaatggctttattgcagcgattaataacaggcaaaaggaagcagggttggtttcccttctttttgttctt catctaagccttctggttttatgggtcagagttccgactgccatcttggacttgtcagcaaaaaaaaaaaaaaaaa (SEQ ID NO: 12198) gagagccccccccccgagactgaaagttttggagattcaggggtcgggggaaagggttcaggaaatggtaattgagtttc caagggatagtgttacaagtggtatgggaggccccctatttctgatagtaatagagaatattttctttgttcattatgat agaacccgtgggataaagagggaaaataaatgttgggagtcccccaggggagaggagagaatccaacagggtgatttgct gatatttgtacgaggagggaaagaatttttcaaagacaaagttggagtgaggagtttttgtagagggaaccaggtggggt acaaagagagagacacactgagccggtgggaagggaagaattaagaggggtgttcccccacactgtatattaagaaagaa aaacaatggggacaggacggcagaagttagagtttcttaaccaggatgagagggggatttcacggtaactaatgagtgat ttcagaccttattccactatcccagggcaatcagatattaatcatgtacaagttgaaatcatgcgtgtcctttgaggtaa gacttacataatcctatttagcataacaggcccccagatccagaaaggggagggttccgcccctatcactgaaggggatc agggatatgaaagtggctcatggttgaccatcacgtttaacaggaatgggcaatcaggaggggtaggtccaattgtgacc aacagaccaaacttccattaatgcttgcggttcttgtggcaaagccagtctgtgaggtttgatggggatggacttggtga gcagagagcagggggacaacgaatcccagaagctgaggggaatggggttccaaagagccgctgctgcctctgggagcacc catgtcagttagtttttccgtacgggactcagggttccagattattcgtttttaaatccttccattcacaatctttaaga agaagaaaaaaaagaagtctgccgctgaccacaagagctctatgccctgcccccatcccacatacacacatcccacactt caattgctccaaacattctgggaacatctcactgccacccacctcacccaactcagcttcacctgcccccaattccctta aggctgagctcccagggccaagactcaagaggctcagagtgagcagagaaaatcctcgcagttaacttggcttccaggaa gtggccactggtgggcgttgtggccattcatgagcaccaaaccacacaaaaagaactttgtccctttcttgtcattttga aagactgtgaaactggagccaattctccatcatcacacaggaagctgagtacttcctacttggtcaggatcttgaaactt gaattcataaaacccagaaagccccagaaacaaagacttcacggacaaagtcccttggaaccagagtaagtgtcacttgt cttttctgtcttatctgttactgtggagggcagtgttgttcaaagacatgcatgcagctaggggctcctcaaaggtaggg ggaattctttgagtaggctgggcaaatgtctaagtagcccatggatgcatctccaaggcaattaatactgtagcaatact gagaatggtggatttataaagctgggtgctcagatgaaatataggcttttttgctaaaaaggaagcttacttgaaggatt ggcttttggttactgattaagaaagtcagtcagtactaagggacaaaaggtgttttctgtggaaacctattcaataagaa attacttggcggggcgcagtggctcacggctgtaatcccagcactttgggagaccgaggcaggtggatcatgaggtcaag agatggagacaatcctggccatatggtgaaaccctgtctctactaaaaataaaaattagccgggcaggtggccgcagcct gttagtcccagctactcaagaggctgaggcaggagaatcactcgaatccgggaggtggaggttgcagtgagctgagattg caccacaacactccagcctggcgacagagcaagagtctgtctgaaaaaaaaaaattgcttgccaaattcccccaagtaaa ggaaaaccaaacatggtgtatgaagaaattatagcaagagggaaatattagctagaaaaatcttggcagatgcaaggatg atttgatactgaacctatctcttaagaagactagaaccaaggatcctcaaaattggcactgctatctttggaagagaggt aggctttcactcacccaaaggcaaggagctggccaggtgatcttggggggcatctgttctgctctactaacaaagacaca ggtcaggattttgttctgaagatagaggggcatggtggctccgtataggtatctacttcataggtggccttggtgggtcc cagatttcaaagaagagatggaaactcccaaaagtttgcacaacctggcaccaggctatgtgccactcactgatccttta gtccccgcaccgagcagtgggacagtgctggactgttcagaatgtggggcctgggcagtgatgtgctggtaaatgttcaa caactgactcttctgaagaaaagatccctgctttataacatttgttgattttcatggtataaatgcccccactgtggtca gtttcaagctaccaacatgctgaatgtggagtggggaagagatgcacgcaattggcatttataaaccagtataagccagc cagcgcaccataggcctgggtgtctttcaccatcacagactgctctactctgctcagagactcaccaactcccaggctgg aagacactagcagtggaaggtccaggatccagggctatactgaccactgtgccagtggccttgaggcagactctgcagta gacaacanccagggctggccnattagatgacaacatgnccttggtccctctcgggcccaacccagacacctcctg (SEQ ID NO: 12199) atggaaactccaaacaccacagaggactatgacacgaccacagagtttgactatggggatgcaactccgtgccagaaggt gaacgagagggcctttggggcccaactgctgccccctctgtactccttggtatttgtcattggcctggttggaaacatcc tggtggtcctggtccttgtgcaatacaagaggctaaaaaacatgaccagcatctacctcctgaacctggccatttctgac ctgctcttcctgttcacgcttcccttctggatcgactacaagttgaaggatgactgggtttttggtgatgccatgtgtaa gatcctctctgggttttattacacaggcttgtacagcgagatctttttcatcatcctgctgacgattgacaggtacctgg ccatcgtccacgccgtgtttgccttgcgggcacggaccgtcacttttggtgtcatcaccagcatcatcatttgggccctg gccatcttggcttccatgccaggcttatacttttccaagacccaatgggaattcactcaccacacctgcagccttcactt tcctcacgaaagcctacgagagtggaagctgtttcaggctctgaaactgaacctctttgggctggtattgcctttgttgg tcatgatcatctgctacacagggattataaagattctgctaagacgaccaaatgagaagaaatccaaagctgtccgtttg atttttgtcatcatgatcatcttttttctcttttggaccccctacaatttgactatacttatttctgttttccaagactt cctgttcacccatgagtgtgagcagagcagacatttggacctggctgtgcaagtgacggaggtgatcgcctacacgcact gctgtgtcaacccagtgatctacgccttcgttggtgagaggttccggaagtacctgcggcagttgttccacaggcgtgtg gctgtgcacctggttaaatggctccccttcctctccgtggacaggctggagagggtcagctccacatctccctccacagg ggagcatgaactctctgctgggttctgactcagaccataggaggccaacccaaaataagcaggcgtgacctgccaggcac actgaccagcagcctggctctcccagccaggttctgactcttggcacagcatggagtccgcctcttggatagagaggaat gtaatggtggcctggggcttctgaggcttctgggcttgagtcttttccatgaacttctcccctggtagaaaagaagatga atgagcaaaaccaaatattccagagactgggactaagtgtaccagagaagggcttggactcaagcaagatttcagatttg tgaccattagcatttgtcaacaaagtcacccacttcccactattgcttgcacaaaccaattaaacccagtagtggtgact gtgggctccattcaaagtgagctcctaagccatgggagacactgatgtatgagga (SEQ ID NO: 12200) ggcacgagcccagaaacaaagacttcacggacaaagtcccttggaaccagagagaagccgggatggaaactccaaacacc acagaggactatgacacgaccacagagtttgactatggggatgcaactccgtgccagaaggtgaacgagagggcctttgg ggcccaactgctgccccctctgtactccttggtatttgtcattggcctggttggaaacatcctggtggtcctggtccttg tgcaatacaagaggctaaaaaacatgaccagcatctacctcctgaacctggccatttctgacctgctcttcctgttcacg cttcccttctggatcgactacaagttgaaggatgactgggtttttggtgatgccatgtgtaagatcctctctgggtttta ttacacaggcttgtacagcgagatctttttcatcatcctgctgacgattgacaggtacctggccatcgtccacgccgtgt ttgccttgcgggcacggaccgtcacttttggtgtcatcaccagcatcatcatttgggccctggccatcttggcttccatg ccaggcttatacttttccaagacccaatgggaattcactcaccacacctgcagccttcactttcctcacgaaagcctacg agagtggaagctgtttcaggctctgaaactgaacctctttgggctggtattgcctttgttggtcatgatcatctgctaca cagggattataaagattctgctaagacgaccaaatgagaagaaatccaaagctgtccgtttgatttttgtcatcatgatc atcttttttctcttttggaccccctacaatttgactatacttatttctgttttccaagacttcctgttcacccatgagtg tgagcagagcagacatttggacctggctgtgcaagtgacggaggtgatcgcctacacgcactgctgtgtcaacccagtga tctacgccttcgttggtgagaggttccggaagtacctgcggcagttgttccacaggcgtgtggctgtgcacctggttaaa tggctccccttcctctccgtggacaggctggagagggtcagctccacatctccctccacaggggagcatgaactctctgc tgggttctgactcagaccataggaggccaacccaaaataagcaggcgtgacctgccaggcacactgagccagcagcctgg ctctcccagccaggttctgactcttggcacagcatggagtcacagccacttgggatagagagggaatgtaatggtggcct ggggcttctgaggcttctggggcttcagtcttttccatgaacttctcccctggtagaaagaagatgaatgagcaaaacca aatattccagagactgggactaagtgtaccagagaagggcttggactcaagcaagatttcagatttgtgaccattagcat ttgtcaacaaagtcacccacttcccactattgcttgcacaaaccaattaaacccagtagtggtgactgtgggctccattc aaagtgagctcctaagccatgggagacactgatgtatgaggaatttctgttcttccatcacctccccccccccgccaccc tcccactgccaagaacttggaaatagtgatttccacagtgactccactctgagtcccagagccaatcagtagccagcatc tgcctccccttcactcccaccgcaggatttgggctcttggaatcctggggaacatagaactcatgacggaagagttgaga cctaacgagaaatagaaatgggggaactactgctggcagtggaactaagaaagcccttaggaagaatttttatatccact aaaatcaaacaattcagggagtgggctaagcacgggccatatgaataacatggtgtgcttcttaaaatagccataaaggg gagggactcatcatttccatttacccttcttttctgactatttttcagaatctctcttcttttcaagttgggtgatatgt tggtagattctaatggctttattgcagcgattaataacaggcaaaaggaagcagggttggtttcccttctttttgttctt catctaagccttctggttttatgggtcagagttccgactgccatcttggacttgtcagcaaaaaaaaaaaaaaaaagaga gccccccccccgagactgaaagttttggagattcaggggtcgggggaaagggttcaggaaatggtaattgagtttccaag ggatagtgttacaagtggtatgggaggccccctatttctgatagtaatagagaatattttctttgttcattatgatagaa cccgtgggataaagagggaaaataaatgttgggagtcccccaggggagaggagagaatccaacagggtgatttgctgata tttgtacgaggagggaaagaatttttcaaagacaaagttggagtgaggagtttttgtagagggaaccaggtggggtacaa agagagagacacactgagccggtgggaagggaagaattaagaggggtgttcccccacactgtatattaagaaagaaaaac aatggggacaggacggcagaagttagagtttcttaaccaggatgagagggggatttcacggtaactaatgagtgatttca gaccttattccactatcccagggcaatcagatattaatcatgtacaagttgaaatcatgcgtgtcctttgaggtaagact tacataatcctatttagcataacaggcccccagatccagaaaggggagggttccgcccctatcactgaaggggatcaggg atatgaaagtggctcatggttgaccatcacgtttaacaggaatgggcaatcaggaggggtaggtccaattgtgaccaaca gaccaaacttccattaatgcttgcggttcttgtggcaaagccagtctgtgaggtttgatggggatggacttggtgagcag agagcagggggacaacgaatcccagaagctgaggggaatggggttccaaagagccgctgctgcctctgggagcacccatg tcagttagtttttccgtacgggactcagggttccagattattcgtttttaaatccttccattcacaatctttaagaagaa gaaaaaaaagaagtctgccgctgaccacaagagctctatgccctgcccccatcccacatacacacatcccacacttcaat tgctccaaacattctgggaacatctcactgccacccacctcacccaactcagcttcacctgcccccaattcccttaaggc tgagctcccagggccaagactcaagaggctcagagtgagcagagaaaatcctcgcagttaacttggcttccaggaagtgg ccactggtgggcgttgtggccattcatgagcaccaaaccacacaaaaagaactttgtccctttcttgtcattttgaaaga ctgtgaaactggagccaattctccatcatcacacaggaagctgagtacttcctacttggtcaggatcttgaaacttgaat tcataaaacccagaaagccccagaaacaaagacttcacggacaaagtcccttggaaccagagtaagtgtcacttgtcttt tctgtcttatctgttactgtggagggcagtgttgttcaaagacatgcatgcagctaggggctcctcaaaggtagggggaa ttctttgagtaggctgggcaaatgtctaagtagcccatggatgcatctccaaggcaattaatactgtagcaatactgaga atggtggatttataaagctgggtgctcagatgaaatataggcttttttgctaaaaaggaagcttacttgaaggattggct tttggttactgattaagaaagtcagtcagtactaagggacaaaaggtgttttctgtggaaacctattcaataagaaatta cttggcggggcgcagtggctcacggctgtaatcccagcactttgggagaccgaggcaggtggatcatgaggtcaagagat ggagacaatcctggccatatggtgaaaccctgtctctactaaaaataaaaattagccgggcaggtggccgcagcctgtta gtcccagctactcaagaggctgaggcaggagaatcactcgaatccgggaggtggaggttgcagtgagctgagattgcacc acaacactccagcctggcgacagagcaagagtctgtctgaaaaaaaaaaattgcttgccaaattcccccaagtaaaggaa aaccaaacatggtgtatgaagaaattatagcaagagggaaatattagctagaaaaatcttggcagatgcaaggatgattt gatactgaacctatctcttaagaagactagaaccaaggatcctcaaaattggcactgctatctttggaagagaggtaggc tttcactcacccaaaggcaaggagctggccaggtgatcttggggggcatctgttctgctctactaacaaagacacaggtc aggattttgttctgaagatagaggggcatggtggctccgtataggtatctacttcataggtggccttggtgggtcccaga tttcaaagaagagatggaaactcccaaaagtttgcacaacctggcaccaggctatgtgccactcactgatcctttagtcc ccgcaccgagcagtgggacagtgctggactgttcagaatgtggggcctgggcagtgatgtgctggtaaatgttcaacaac tgactcttctgaagaaaagatccctgctttataacatttgttgattttcatggtataaatgcccccactgtggtcagttt caagctaccaacatgctgaatgtggagtggggaagagatgcacgcaattggcatttataaaccagtataagccagccagc gcaccataggcctgggtgtctttcaccatcacagactgctctactctgctcagagactcaccaactcccaggctggaaga cactagcagtggaaggtccaggatccagggctatactgaccactgtgccagtggccttgaggcagactctgcagtagaca acanccagggctggccnattagatgacaacatgnccttggtccctctcgggcccaacccagacacctcctgatggaaact ccaaacaccacagaggactatgacacgaccacagagtttgactatggggatgcaactccgtgccagaaggtgaacgagag ggcctttggggcccaactgctgccccctctgtactccttggtatttgtcattggcctggttggaaacatcctggtggtcc tggtccttgtgcaatacaagaggctaaaaaacatgaccagcatctacctcctgaacctggccatttctgacctgctcttc ctgttcacgcttcccttctggatcgactacaagttgaaggatgactgggtttttggtgatgccatgtgtaagatcc ctc tgggttttattacacaggcttgtacagcgagatctttttcatcatcctgctgacgattgacaggtacctggccatcgtcc acgccgtgtttgccttgcgggcacggaccgtcacttttggtgtcatcaccagcatcatcatttgggccctggccatcttg gcttccatgccaggcttatacttttccaagacccaatgggaattcactcaccacacctgcagccttcactttcctcacga aagcctacgagagtggaagctgtttcaggctctgaaactgaacctctttgggctggtattgcctttgttggtcatgatca tctgctacacagggattataaagattctgctaagacgaccaaatgagaagaaatccaaagctgtccgtttgatttttgtc atcatgatcatcttttttctcttttggaccccctacaatttgactatacttatttctgttttccaagacttcctgttcac ccatgagtgtgagcagagcagacatttggacctggctgtgcaagtgacggaggtgatcgcctacacgcactgctgtgtca acccagtgatctacgccttcgttggtgagaggttccggaagtacctgcggcagttgttccacaggcgtgtggctgtgcac ctggttaaatggctccccttcctctccgtggacaggctggagagggtcagctccacatctccctccacaggggagcatga actctctgctgggttctgactcagaccataggaggccaacccaaaataagcaggcgtgacctgccaggcacactgaccag cagcctggctctcccagccaggttctgactcttggcacagcatggagtccgcctcttggatagagaggaatgtaatggtg gcctggggcttctgaggcttctgggcttgagtcttttccatgaacttctcccctggtagaaaagaagatgaatgagcaaa accaaatattccagagactgggactaagtgtaccagagaagggcttggactcaagcaagatttcagatttgtgaccatta gcatttgtcaacaaagtcacccacttcccactattgcttgcacaaaccaattaaacccagtagtggtgactgtgggctcc attcaaagtgagctcctaagccatgggagacactgatgtatgagga (SEQ ID NO: 12201) atgacaacctcactagatacagttgagacctttggtaccacatcctactatgatgacgtgggcctgctctgtgaaaaagc tgataccagagcactgatggcccagtttgtgcccccgctgtactccctggtgttcactgtgggcctcttgggcaatgtgg tggtggtgatgatcctcataaaatacaggaggctccgaattatgaccaacatctacctgctcaacctggccatttcggac ctgctcttcctcgtcacccttccattctggatccactatgtcagggggcataactgggtttttggccatggcatgtgtaa gc cctctcagggttttatcacacaggcttgtacagcgagatctttttcataatcctgctgacaatcgacaggtacctgg ccattgtccatgctgtgtttgcccttcgagcccggactgtcacttttggtgtcatcaccagcatcgtcacctggggcctg gcagtgctagcagctcttcctgaatttatcttctatgagactgaagagttgtttgaagagactctttgcagtgctcttta cccagaggatacagtatatagctggaggcatttccacactctgagaatgaccatcttctgtctcgttctccctctgctcg ttatggccatctgctacacaggaatcatcaaaacgctgctgaggtgccccagtaaaaaaaagtacaaggccatccggctc atttttgtcatcatggcggtgtttttcattttctggacaccctacaatgtggctatccttctctcttcctatcaatccat cttatttggaaatgactgtgagcggagcaagcatctggacctggtcatgctggtgacagaggtgatcgcctactcccact gctgcatgaacccggtgatctacgcctttgttggagagaggttccggaagtacctgcgccacttcttccacaggcacttg ctcatgcacctgggcagatacatcccattccttcctagtgagaagctggaaagaaccagctctgtctctccatccacagc agagccggaactctctattgtgttttag (SEQ ID NO: 12202) tttttcttcttctatcacagggagaagtgaaatgacaacctcactagatacagttgagacctttggtaccacatcctact atgatgacgtgggcctgctctgtgaaaaagctgataccagagcactgatggcccagtttgtgcccccgctgtactccctg gtgttcactgtgggcctcttgggcaatgtggtggtggtgatgatcctcataaaatacaggaggctccgaattatgaccaa catctacctgctcaacctggccatttcggacctgctcttcctcgtcacccttccattctggatccactatgtcagggggc ataactgggtttttggccatggcatgtgtaagctcctctcagggttttatcacacaggcttgtacagcgagatctttttc ataatcctgctgacaatcgacaggtacctggccattgtccatgctgtgtttgcccttcgagcccggactgtcacttttgg tgtcatcaccagcatcgtcacctggggcctggcagtgctagcagctcttcctgaatttatcttctatgagactgaagagt tgtttgaagagactctttgcagtgctctttacccagaggatacagtatatagctggaggcatttccacactctgagaatg accatcttctgtctcgttctccctctgctcgttatggccatctgctacacaggaatcatcaaaacgctgctgaggtgccc cagtaaaaaaaagtacaaggccatccggctcatttttgtcatcatggcggtgtttttcattttctggacaccctacaatg tggctatccttctctcttcctatcaatccatcttatttggaaatgactgtgagcggagcaagcatctggacctggtcatg ctggtgacagaggtgatcgcctactcccactgctgcatgaacccggtgatctacgcctttgttggagagaggttccggaa gtacctgcgccacttcttccacaggcacttgctcatgcacctgggcagatacatcccattccttcctagtgagaagctgg aaagaaccagctctgtctctccatccacagcagagccggaactctctattgtgttttaggtcagatgcagaaaattgcct aaagaggaaggaccaaggagatgaagcaaacacattaagccttccacactcacctctaaaacagtccttcaaacttccag t (SEQ ID NO: 12203) aatccttttcctggcacctctgatatccttttgaaattcatgttaaagaatccctaggctgctatcacatgtggcatctt tgttgagtacatgaataaatcaactggtgtgttttacggaggatgattatgcttcattgtgggattgtatttttcttctt ctatcacagggagaagtgaaatgacaacctcactagatacagttgagacctttggtaccacatcctactatgatgacgtg ggcctgctctgtgaaaaagctgataccagagcactgatggcccagtttgtgcccccgctgtactccctggtgttcactgt gggcctcttgggcaatgtggtggtggtgatgatcctcataaaatacaggaggctccgaattatgaccaacatctacctgc tcaacctggccatttcggacctgctcttcctcgtcacccttccattctggatccactatgtcagggggcataactgggtt tttggccatggcatgtgtaagctcctctcagggttttatcacacaggcttgtacagcgagatctttttcataatcctgct gacaatcgacaggtacctggccattgtccatgctgtgtttgcccttcgagcccggactgtcacttttggtgtcatcaeca gcatcgtcacctggggcctggcagtgctagcagctcttcctgaatttatcttctatgagactgaagagttgtttgaagag actctttgcagtgctctttacccagaggatacagtatatagctggaggcatttccacactctgagaatgaccatcttctg tctcgttetccctctgctcgttatggccatctgctacacaggaatcatcaaaacgctgctgaggtgccccagtaaaaaaa agtacaaggccatccggctcatttttgtcatcatggcggtgtttttcattttctggacaccctacaatgtggctatcctt ctctcttcctatcaatccatcttatttggaaatgactgtgagcggacgaagcatctggacctggtcatgctggtgacaga ggtgatcgcctactcccactgctgcatgaacccggtgatctacgcctttgttggagagaggttccggaagtacctgcgcc acttcttccacaggcacttgctcatgcacctgggcagatacatcccattccttcctagtgagaagctggaaagaaccagc tctgtctctccatccacagcagagccggaactctctattgtgttttaggtagatgcagaaaattgcctaaagaggaagga ccaaggagatnaagcaaacacattaagccttccacactcacctctaaaacagtccttcaaaccttccagtgcaacactga agctcttaagacactgaaatatacacacagcagtagcagtagatgcatgtaccctaaggtcattaccacaggccagggct gggcagcgtactcatcatcaacctaaaaagcagagctttgcttctctctctaaaatgagttacctatattttaatgcacc tgaatgttagatagttactatatgccgctacaaaaaggtaaaactttttatattttatacattaacttcagccagctatt atataaataaaacattttcacacaatacaataagttaactattttattttctaatgtgcctagttctttccctgcttaat gaaaagctt (SEQ ID Nθ:12204) atgacaacctcactagatacagttgagacctttggtaccacatcctactatgatgacgtgggcctgctctgtgaaaaagc tgataccagagcactgatggcccagtttgtgcccccgctgtactccctggtgttcactgtgggcctcttgggcaatgtgg tggtggtgatgatcctcataaaatacaggaggctccgaattatgaccaacatctacctgctcaacctggccatttcggac ctgctcttcctcgtcacccttccattctggatccactatgtcagggggcataactgggtttttggccatggcatgtgtaa gctcctctcagggttttatcacacaggcttgtacagcgagatctttttcataatcctgctgacaatcgacaggtacctgg ccattgtccatgctgtgtttgcccttcgagcccggactgtcacttttggtgtcatcaccagcatcgtcacctggggcctg gcagtgctagcagctcttcctgaatttatcttctatgagactgaagagttgtttgaagagactctttgcagtgctcttta cccagaggatacagtatatagctggaggcatttccacactctgagaatgaccatcttctgtctcgttctccctctgctcg ttatggccatctgctacacaggaatcatcaaaacgctgctgaggtgccccagtaaaaaaaagtacaaggccatccggctc atttttgtcatcatggcggtgtttttcattttctggacaccctacaatgtggctatccttctctcttcctatcaatccat cttatttggaaatgactgtgagcggagcaagcatctggacctggtcatgctggtgacagaggtgatcgcctactcccact gctgcatgaacccggtgatctacgcctttgttggagagaggttccggaagtacctgcgccacttcttccacaggcacttg ctcatgcacctgggcagatacatcccattccttcctagtgagaagctggaaagaaccagctctgtctctccatccacagc agagccggaactctctattgtgttttagtttttcttcttctatcacagggagaagtgaaatgacaacctcactagataca gttgagacctttggtaccacatcctactatgatgacgtgggcctgctctgtgaaaaagctgataccagagcactgatggc ccagtttgtgcccccgctgtactccctggtgttcactgtgggcctcttgggcaatgtggtggtggtgatgatcctcataa aatacaggaggctccgaattatgaccaacatctacctgctcaacctggccatttcggacctgctcttcctcgtcaccctt ccattctggatccactatgtcagggggcataactgggtttttggccatggcatgtgtaagctcctctcagggttttatca cacaggcttgtacagcgagatctttttcataatcctgctgacaatcgacaggtacctggccattgtccatgctgtgtttg cccttcgagcccggactgtcacttttggtgtcatcaccagcatcgtcacctggggcctggcagtgctagcagctcttcct gaatttatcttctatgagactgaagagttgtttgaagagactctttgcagtgctctttacccagaggatacagtatatag ctggaggcatttccacactctgagaatgaccatcttctgtctcgttctccctctgctcgttatggccatctgctacacag gaatcatcaaaacgctgctgaggtgccccagtaaaaaaaagtacaaggccatccggctcatttttgtcatcatggcggtg tttttcattttctggacaccctacaatgtggctatccttctctcttcctatcaatccatcttatttggaaatgactgtga gcggagcaagcatctggacctggtcatgctggtgacagaggtgatcgcctactcccactgctgcatgaacccggtgatct acgcctttgttggagagaggttccggaagtacctgcgccacttcttccacaggcacttgctcatgcacctgggcagatac atcccattccttcctagtgagaagctggaaagaaccagctctgtctctccatccacagcagagccggaactctctattgt gttttaggtcagatgcagaaaattgcctaaagaggaaggaccaaggagatgaagcaaacacattaagccttccacactca cctctaaaacagtccttcaaacttccagtaatccttttcctggcacctctgatatccttttgaaattcatgttaaagaat ccctaggctgctatcacatgtggcatctttgttgagtacatgaataaatcaactggtgtgttttacggaggatgattatg cttcattgtgggattgtatttttcttcttctatcacagggagaagtgaaatgacaacctcactagatacagttgagacct ttggtaccacatcctactatgatgacgtgggcctgctctgtgaaaaagctgataccagagcactgatggcccagtttgtg cccccgctgtactccctggtgttcactgtgggcctcttgggcaatgtggtggtggtgatgatcctcataaaatacaggag gctccgaattatgaccaacatctacctgctcaacctggccatttcggacctgctcttcctcgtcacccttccattctgga tccactatgtcagggggcataactgggtttttggccatggcatgtgtaagctcctctcagggttttatcacacaggcttg tacagcgagatctttttcataatcctgctgacaatcgacaggtacctggccattgtccatgctgtgtttgcccttcgagc ccggactgtcacttttggtgtcatcaccagcatcgtcacctggggcctggcagtgctagcagctcttcctgaatttatct tctatgagactgaagagttgtttgaagagactctttgcagtgctctttacccagaggatacagtatatagctggaggcat ttccacactctgagaatgaccatcttctgtctcgttctccctctgctcgttatggccatctgctacacaggaatcatcaa aacgctgctgaggtgccccagtaaaaaaaagtacaaggccatccggctcatttttgtcatcatggcggtgtttttcattt tctggacaccctacaatgtggctatccttctctcttcctatcaatccatcttatttggaaatgactgtgagcggacgaag catctggacctggtcatgctggtgacagaggtgatcgcctactcccactgctgcatgaacccggtgatctacgcctttgt tggagagaggttccggaagtacctgcgccacttcttccacaggcacttgctcatgcacctgggcagatacatcccattcc ttcctagtgagaagctggaaagaaccagctctgtctctccatccacagcagagccggaactctctattgtgttttaggta gatgcagaaaattgcctaaagaggaaggaccaaggagatnaagcaaacacattaagccttccacactcacctctaaaaca gtccttcaaaccttccagtgcaacactgaagctcttaagacactgaaatatacacacagcagtagcagtagatgcatgta ccctaaggtcattaccacaggccagggctgggcagcgtactcatcatcaacctaaaaagcagagctttgcttctctctct aaaatgagttacctatattttaatgcacctgaatgttagatagttactatatgccgctacaaaaaggtaaaactttttat attttatacattaacttcagccagctattatataaataaaacattttcacacaatacaataagttaactattttattttc taatgtgcctagttctttccctgcttaatgaaaagctt (SEQ ID NO: 12205) tctagagccaaggtcacggaagcccagagggcatcttgtggctcgggagtagctctctgctgtcttctcagctctgctga caatacttgagattttcagatgtcaccaaccaccaagagagcttgatatgactgtatatagtatagtcataaagaacctg aacttgaccatatacttatgtcatgtggaaaatttctcatagcttcagatagattatatctggagtgaagaatcctgcca cctatgtatctggcatagtgtgagtcctcataaatgcttactggtttgaagggcaacaaaatagtgaacagagtgaaaat ccccactaagatcctgggtccagaaaaagatgggaaacctgtttagctcacccgtgagcccatagttaaaactctttaga caacaggttttttccgtttacagagaacaataatattgggtggtgagcatctgtgtgggggttggggtgggataggggat acggggagagtggagaaaaagggggcacagggttaatgtgaagtccaggatccccctctacatttaaagttggtttaagt tggctttaattaatagcaactcttaagataatcagaattttcttaaccttttagccttactgttgaaaagccctgtgatc ttgtacaaatcatttgcttcttggatagtaatttcttttactaaaatgtgggcttttgactagatgaatgtaaatgttct tctagctctgatatcctttattctttatattttctaacagattctgtgtagtgggatgagcagagaacaaaaacaaaata atccagtgagaaaagcccgtaaataaactttcagaccagagatctattctctagcttattttaagctcaacttaaaagga agaactgttctctgattcttttcgccttcaatacacttaatgatttaactccaccctccttcaaaagaaacagcatttcc tacttttatactgtctatatgattgatttgcacagctcatctggccagaagagctgagacatccgttcccctacaagaaa ctctccccggtaagtaacctctcagctgcttggcctgttagttagcttctgagatgagtaaaagactttacaggaaaccc atagaagacatttggcaaacaccaagtgctcatacaattatcttaaaatataatctttaagataaggaaagggtcacagt ttggaatgagtttcagacggttataacatcaaagatacaaaacatgattgtgagtgaaagactttaaagggagcaatagt attttaataactaacaatccttacctctcaaaagaaagatttgcagagagatgagtcttagctgaaatcttgaaatctta tcttctgctaaggagaactaaaccctctccagtgagatgccttctgaatatgtgcccacaagaagttgtgtctaagtctg gttctcttttttctttttcctccagacaagagggaagcctaaaaatggtcaaaattaatattaaattacaaacgccaaat aaaattttcctctaatatatcagtttcatggcacagttagtatataattctttatggttcaaaattaaaaatgagctttt ctaggggcttctctcagctgcctagtctaaggtgcagggagtttgagactcacagggtttaataagagaaaattc cagc tagagcagctgaacttaaatagactaggcaagacagctggttataagactaaactacccagaatgcatgacattcatctg tggtggcagacgaaacattttttattatattatttcttgggtatgtatgacaactcttaattgtggcaactcaaactaca aacacaaacttcacagaaaatgtgaggattttacaattggctgttgtcatctatgaccttccctgggacttgggcacccg gccatttcactctgactacatcatgtcaccaaacatctgatggtcttgccttttaattctctttttgaggactgagaggg agggtagcatggtagttaagagtgcaggcttcccgcattcaaaatcggttgcttactagctgtgtggctttgagcaagtt actcaccctctctgtgcttcaaggtccttgtctgcaaaatgtgaaaaatatttcctgcctcataaggttgccctaaggat taaatgaatgaatgggtatgatgcttagaacagtgattggcatccagtatgtgccctcgaggcctcttaattattactgg cttgctcatagtgcatgttctttgtgggctaactctagcgtcaataaaaatgttaagactgagttgcagctgggcatggt ggctcatgcctgtaatcccagcattctaggaggctgaggcaggaggatcgcttgagcccaggagttcgagaccagcctgg gcaacatagtgtgatcttgtatctataaaaataaacaaaattagcttggtgtggtggcgcctgtagtccccagccacttg gaggggtgaggtgagaggattgcttgagcccgggatgatccaggctgcagtgagccatgatcgtgccactgcactccagc ctgggcgacagagtgagaccctgtctcacaacaacaacagcaacaaaaaggctgagctgcaccatgcttgacccagtttc ttaaaattgttgtcaaagcttcattcactccatggtgctatagagcacaagattttatttggtgagatggtgctttcatg aattcccccaacagagccaagctctccatctagtggacagggaagctagcagcaaaccttcccttcactacaaaacttca ttgcttggccaaaaagagagttaattcaatgtagacatctatgtaggcaattaaaaacctattgatgtataaaacagttt gcattcatggagggcaactaaatacattctaggactttataaaagatcactttttatttatgcacagggtggaacaagat g (SEQ ID NO: 12206) agaagagctgagacatccgttcccctacaagaaactctccccgggtggaacaagatggattatcaagtgtcaagtccaat ctatgacatcaattattatacatcggagccctgccaaaaaatcaatgtgaagcaaatcgcagcccgcctcctgcctccgc tctactcactggtgttcatctttggttttgtgggcaacatgctggtcatcctcatcctgataaactgcaaaaggctgaag agcatgactgacatctacctgctcaacctggccatctctgacctgtttttccttcttactgtccccttctgggctcacta tgctgccgcccagtgggactttggaaatacaatgtgtcaactcttgacagggctctattttataggcttcttctctggaa tcttcttca catcctcctgacaatcgataggtacctggctgtcgtccatgctgtgtttgctttaaaagccaggacggtc acctttggggtggtgacaagtgtgatcacttgggtggtggctgtgtttgcgtctctcccaggaatcatctttaccagatc tcaaaaagaaggtcttcattacacctgcagctctcattttccatacagtcagtatcaattctggaagaatttccagacat taaagatag catcttggggctggtcctgccgctgcttgtcatggtcatctgctactcgggaatcctaaaaactctgctt cggtgtcgaaatgagaagaagaggcacagggctgtgaggcttatcttcaccatcatgattgtttattttctcttctgggc tccctacaacattgtccttctcctgaacaccttccaggaattctttggcctgaataattgcagtagctctaacaggttgg accaagctatgcaggtgacagagactcttgggatgacgcactgctgcatcaaccccatcatctatgcctttgtcggggag aagttcagaaactacctcttagtcttcttccaaaagcacattgccaaacgcttctgcaaatgctgttctattttccagca agaggctcccgagcgagcaagctcagtttacacccgatccactggggagcaggaaatatctgtgggcttgtgacacggac tcaagtgggctggtgacccagtcagagttgtgcacatggcttagttttcatacacagcctgggctgggggtggggtggga gaggtcttttttaaaaggaagttactgttatagagggtctaagattcatccatttatttggcatctgtttaaagtagatt agatcttttaagcccatcaattatagaaagccaaatcaaaatatgttgatgaaaaatagcaacctttttatctccccttc acatgcatcaagttattgacaaactctcccttcactccgaaagttccttatgtatatttaaaagaaagcctcagagaatt gctgattcttgagtttagtgatctgaacagaaataccaaaattatttcagaaatgtacaactttttacctagtacaaggc aacatataggttgtaaatgtgtttaaaacaggtctttgtcttgctatggggagaaaagacatgaatatgattagtaaaga aatgacacttttcatgtgtgatttcccctccaaggtatggttaataagtttcactgacttagaaccaggcgagagacttg tggcctgggagagctggggaagcttcttaaatgagaaggaatttgagttggatcatctattgctggcaaagacagaagcc tcactgcaagcactgcatgggcaagcttggctgtagaaggagacagagctggttgggaagacatggggaggaaggacaag gctagatcatgaagaaccttgacggcattgctccgtctaagtcatgagctgagcagggagatcctggttggtgttgcaga aggtttactctgtggccaaaggagggtcaggaaggatgagcatttagggcaaggagaccaccaacagccctcaggtcagg gtgaggatggcctctgctaagctcaaggcgtgaggatgggaaggagggaggtattcgtaaggatgggaaggagggaggta ttcgtgcagcatatgaggatgcagagtcagcagaactggggtggatttggtttggaagtgagggtcagagaggagtcaga gagaatccctagtcttcaagcagattggagaaacccttgaaaagacatcaagcacagaaggaggaggaggaggtttaggt caagaagaagatggattggtgtaaaaggatgggtctggtttgcagagcttgaacacagtctcacccagactccaggctgt ctttcactgaatgcttctgacttcatagatttccttcccatcccagctgaaatactgaggggtctccaggaggagactag atttatgaatacacgaggtatgaggtctaggaacatacttcagctcacacatgagatctaggtgaggattgattacctag tagtcatttcatgggttgttgggaggattctatgaggcaaccacaggcagcatttagcacatactacacattcaataagc a caaactcttagttactcattcagggatagcactgagcaaagcattgagcaaaggggtcccatataggtgagggaagcc tgaaaaactaagatgctgcctgcccagtgcacacaagtgtaggtatcattttctgcatttaaccgtcaataggcaaaggg gggaagggacatattcatttggaaataagctgccttgagccttaaaacccacaaaagtacaatttaccagcctccgtatt tcagactgaatgggggtggggggggcgccttaggtacttattccagatgccttctccagacaaaccagaagcaacagaaa aaatcgtctctccctccctttgaaatgaatataccccttagtgtttgggtatattcatttcaaagggagagagagaggtt tttttctgttctttctcatatgattgtgcacatacttgagactgttttgaatttgggggatggctaaaaccatcatagta caggtaaggtgagggaatagtaagtggtgagaactactcagggaatgaaggtgtcagaataataagaggtgctactgact ttctcagcctctgaatatgaacggtgagcattgtggctgtcagcaggaagcaacgaagggaaatgtctttccttttgctc ttaagttgtggagagtgcaacagtagcataggaccctaccctctgggccaagtcaaagacattctgacatcttagtattt gcatattcttatgtatgtgaaagttacaaattgcttgaaagaaaatatgcatctaataaaaaacaccttctaaaataaaa aaaaaaaaaaaaaaaaaaaaaaa (SEQ ID NO: 12207) aagcttcagtatgcaaattttcaatgacatgtgcctgtggattctgaaaattcacagatctgtctatccttagctgagac tgaaggcatctacttcccaatgaccaaatcctggtgctgtggcgacactgagcaggaactccattagaatatcaatatca ctctgcagacattccatgatgtaagctatgttttctcttgttgcaattacacttaatttaccaccagctgcttcaatgtc atgggctatcttgaaaaatgaagctcctttcgtagtcaaactggatgcaagacacagcaaatgagaagttactaaattgt tggagtcctcatagctactgcctgctttaatgaacaaaccaattcttgatgcagggcatagttttccaaaggagaaatca taaaaccatttggaaatttgatgatctcaaggtcctgatgatgtggagccactcctatgggggtagctgtggctttaact ttgggggcaactttgagggaataaagtctcaaaaagagggaataaagtctcaagattgttcgtgacccatagtaacttct ggcttaaaggaccattcggcaagtttttaaatgtattttctataatttccatgtagttctttatattttctatttcttat ttaaaacctctattttagctcgtttcctttgacactgctctggcagggaaaggggtggcactgcctcattactgccaggt aggggtagaagtccattatccacttggtctccattgatacccaaagtggggagaggctcctgttactgctggtgagggtg ggagtccccccactaagtttctgctaatactgtcctggtggcttgctactattcccatgaagcctccactgatactacat tacttttgggtggtggcaaatgtcctgcctctccactagccctcctgctctaaaacaacccgagtagggagtgggaagga agctttgttactggtaggtgggagctgaagtccagacttgccacattgtcccactgatgctacagggaggaggaagcggg ccacattactgcctgatagggatgaaagccccagctccctacctggccttcgctgataccagcctgctacaggagtgaag agagatttgaaggcctcaatatagcctgtcgagggtggaagtcttgctcccaatgggcctttagcagcatgggtgggtgt ggggccatagctgtctctgtactgcttggctagagtggagtatttgaggtccaaaagttttctgtctttctagccctttg gttagaaagagcagacttttgttggaagtatttttttgtgtttacctgttgtatttccaggttcctagcttctccagcac agtctgggatgtgtgagacacagagaaaatccagtgatgttactaccgtatggtttcttgggtcccaacgtctctagcta atctgctccaccttttggagttttcttatttgttttagatcagggatttagtcatatttaataggagaaatatggaaaaa tacttctactctatcttcctggaagttcctgtttattttttatgtccttttcctctggctagaccgtaagagacttacga aacaaacacttacacattctactaaactcaatgtccaaagtttgtgaacttcttgaatattgcttgttcatttccacccc cagtcactgactgaatctccctgctgtctgtctacaatgccaatgagcttctggttaacttcttctcatgcatgcttagg caacaacttcccagttttactacacttgcccatccctagttttgttgttgcttaatcccttggcctagtgccaccatact cctccagcagagcaaccaattcttacattataggacagcacatatccactaaaaacagttcatgccacaccaaccacatt tccctttgtcaacaaaattacttgatagataattccaggaatgcctgatgaagctgattgacaacaagatatttggcaga ctctctgctgcctatacataccttagcatgtggaactcaagtaatgagaggtccatttaattggattgaattgggctgga taggattggattgaatcctgtgggatggctaggctaaattagaaatgaagactagtttaacagcagtatccaaggatagt tgactaatgagttaattttactctcaaagacagtctttagtagtaagctgtaatgcattatatcaaactattttccagtc aatgatttataagttacttgaataaggatgctaaagatgtgccttattgaaatggcaattagcacaaagttgggaatgaa atctaattagttaaataacagaatcacataaaaaaggacttgaataaatgtagcatcctaccatgttcctggatagaaag actgctatcgtaaagatattcattctcctcaggttaaattataaactcaatgcaattcaacaggattttaaaaaactaga caaagtgattccaagtttacgtggaaaataaaatgtgagggaccaaacaatatttgaaaaagaaagagaataaaatctca tccttccagataccacaatgtattataaagcaatagtaattaacatgagggcagaaatgagcaagcaagtgaacaaaata agacagatagtcacaggaaactcatatatttataggtgctttgcgtataatgaagatggtccttcaaatcagttgggaaa agatgggttattcaataaatggtgttgggtaaaattggttatacattggtgagaaataaagtgaaactcctactttgtat catatgcaaaaaatagattccagacagatgaaatatttaaatgtaaaaaataaaattctaaaactactagaaaaaaaaga agaatatttttattcctttgaaatagaaaaggtcttactaagcaaaacacagaagtaataaatgaataaatgaagacaaa tatgataaaaataagttaaaaatataagcaatctttctttgtttttttttcacctttcctagaaaaaaatatataggcaa cttgttaagcaaggtagattacaagaaaatatttacaacatttgacaggccacagattattatccagcctcatctgataa gaaaacttcaacataaagatatctgttttttttcttataaggttcctcaaagtgagccaatcacttcttaagctgaacaa aaaacaaaacagaagtgatcttttccaataatgaaaacaaacattgacagagcagctgtaggatcctttcaggcaaatta tgaaaaggtgccctttctcagaaaccacagttaccattcagctttgtgaccagaggtttgactgtaccctagtccctact agcaacccaaccacataaccaacttcaaaggtcctgaatgactgtgttgtacttaatggcagatgatctatctcccattt ttgtcctaaggattttccaagataatatatttctgcatttgttttgcttttacttcactccaaattgaaatctatttgtg ggataagactaaagaaatgcttataggaaaattgatagcaccaaattcctatcttaaaaaatgaaaaaggtttcaaatca atgacctcagcttttactttaagaaaatagaaaaagcaggataagctaaagccaaagtaaacagaagaaaggaaattata aagataagagcagaaatcaatgaatagaaaacaaaagaaaaaaatcaaaccaaacagctgattctttaagcagatctata aaattgataaaactctagccagattgatcaagtaaaaaagagagaagacacaaattaccagtattaagaatgagagaggc aatatcactacagatcctacagatataaaaagtataagggcatactttgaataattttatgactataaattaggcaactt agataaaacaaatttcttgaaagacacaaacaaccaaagctcacctaaaatactcacaaattgaatagtcttatagctat tacaaaattgaggccaggcgcagtggctcaagcctttaatcccagcactttgggagggctaggaaggcggatcacgaggt caggagtttgagaccagcctgactaacatggtgaaaccctgtctctactaaaagtacaaaaattagccaggcttggtggt gcgtgcctgtaatcccatctactcaggagactgaggcaggagaattgcttgaacctgggaggcaaagttgtggtgagccg agatcgcgccactgcacttcagcctgggcaacagaacaagactccgtctcaaaaaaaaaaaaaaaaaaaaaaattgaaat ta agttaaaagtcttcccacaaagcaaactctagacccagatggcttcaatggtaaattctactggacaatcaaacagg aaacagtaataattctccacaatgtctttcataaaattgatgcggaggagatactctccaactcattctatgaaactagc attaccctgataccaaaatcataoagagacagtgtaggaaaacaacagatcagtatccttcatgaacataaatgaagtac aatgcagtcttatgcataaatcagagcttcattgttctacagataaggtaatgtaggattgttggttgcccctccaggtc tgttaaattcacctccttccccagagagcatccttcttaaggacagggagcctcaatatgtcagtcctcacagcacctcc ctcagtcttcagcacttaccagctcatcaccacaaccgataccacattggataatttcatgaattactttagagcaaatg caagagaaaaaatggatttttatataggagaagaaggaggaaattcttgtggatttggtacagaatagggccaagggaaa attacagatgtaaaaagaaaagtgtgtgaaatagtatccttagtgctcacaaatacaatgatttcattgtttttaaaaat aaaaaatgacaaatgtctaatgcttggtggtaatgctttattgaatgtgtgttatacactggttcctcattcctgaagtt agaaataataccttcctcttttcatttggttatgtttgctgaaacaaatcaaaggctgagattgaaacacatgctacttc aggtggatgaccttactactaagctcatcacaacagcacttacagctgaagaccccagagtcctacctaacttttgtcac aacccagattttggccatgtagttctgggccttaccattaaagcagacagaagtcagaggaatgactcctttccacttga agtgagctgcaggcttctaggaaaggcaagatgcacatttccctcctgtggagcataaagcctttgtaattcaggactta ggacccatatggatttgaaatattatgacattggagctggagtggttggggacaacaccagtagtgttataggccatgga atgtcaaaagaacatggaaccctgttaaaatcattaaacatcaaaactctcccctcctctggtgatatggtttggctgtg tccccatccaaatctcatcttgaactcccatgtgttgtgggaggcacccagtgggaggtaattgaatcatgggggcaggt ctttcccatgctgttttcacgatactgaataagtctcacaagatctgatggttttataaaggggagcttccctgcacaag ctctcttctcttgtctgccaccatgtgagacatgcctttcaccttccgccatgattgtgaggcctccccaaccatgtgga acttttaagttcattaaacctcttccttttgtaaattgctcagtctcaaatatgtctttatcagcaacgtgaaaacagac tatctgattttctgtgggatgtggattatgaccatggacagagcataactgggacagagctggaaaaaatattaattagg tgcttaaaaatatttgttagaactatcttcatgaatgagaatcaatcctgtttccatggtgattcaccaggcatcaattc caagcatccatgaatcagaaaagtcctatcttctcttagttatcatccaggactccaaggaaccataattagccaacctg ttcacatttccttttcattcactagcctcgaagtttccaggggacagggactctgtcctattcatttctgtaaccttacc acctgacccagaatagctgttccctgaagatttggtggattataaatgtggatgtcttatttctttgaaagtgtgagctt caggtactgatcacgttattccaattatcaatttagtatctttcttcaccattaaactgtgaaattcttgagggaagaac ctatgactgatttatctctgtaaactcatgccaccagtattcaaaatcacacctagcacatagtaaacactcaatgtttg ttgaatgactgaaggaatggatgaaaatgaacctccttgcttctgaccagtggatgagttgcttggccgtgttcctacag cctagagctcatcccctaaagcatctgaagttacccattagtgcaatggttcttgaacgctggtgttgatcagaatcatc tggatgcccaggttctctgaaataagatagggtctaggcatttgtatttttaccaaggaggtgtgatggagtcagatgca agaaggctagttgaagaaaccacatgagagtttagtgtagtgtattagaagactggtttggctctgtcgctagtggctac atcatcttgctcaagtcatgccagtctcaggacctcattcagtctcttcagctgtaatatgggtgggttgcaccacataa ccagaaagatcccttccagctctacccacttacaacatggtcaaatttggtctgattttttaaatcgtagtacaatatat atgacataaaattcaccattttagccactttaaatgtacaattctgtagcattaactacattcacattgttgtgcaacca tcactaccgtctacttccagaactcttcatcttgcaaaactgaacctctgttgtcattagtcactaactattcctctccc cccctccttctaggccctggcaatcaccattctactttctgtcgctatgaatttgactactctaggtaacttatataagt ggaatcacagcatttgccctattatgactggtttagttgacttagcacaacctcctaaggctcaaccacattttagcatg tgtcagaattttctttgtttttaaggctgaataatattctgttgtatctgtaaataacatctttattcatttgtccatca acagactgttgagttcctcccatcttttgactattgtgaaaaatgctgctatgaacctgagtgtacagacatctggttga gtactgctttcaattcattgtttatatggatcatatggtaattttatgtttaatttttttggaactgctacattgttttc cacagtgtacatcattttacatttccatcagcaatgcacaaaggttccaatttctccacattcttaccaacattttttat tttctgtttcttatttatttgtttatttattctgagacagagtctcactctgtcacctaggctggagtgcagcagggtga tctcagctcactgcaacctctgcctcccatgttcaagtgattctcctccctcagcctcccaagtaaatggaattacaggt gcccaccaccacgcccaggtaatttttgcattttttttagtagtgatgaggtttcaccatgttggtcaggctggtcttga actcctgacctcaagtgatccacccgcctcagcctcccaaagtgctgggattacaggtatgaaccactgcacccaggcca ttttttgctttttagataatagtcatcctagtgggtatgaagtggtatttcattgtggttttgatttatatttccctaat gatcagtgatattgagcatctttcaagtgcttattggccattttcttctttggagaaatgtctatgcaagtcctttgctc attttttaatccagttgctttttgttattctttttgatttgaaagtgttctttatacctcttgtatactaatcccttatc agatatgatttataaatattttcttcttttccatggattgccctttttactctgttgatagtgttctttgatacaaaata atttttaatttgaatgaagcccaattaatctatttttgtttcttttgttgcctgtgcttttggtgtcc atccaagaaac tgttgccaaatccaatgtcataaagctttttcccatgcttccttctaagagttttgtagttacagctcttgtatttaggt atttgactattttgagttaatttttgtacatcgtataaaataagaatccaatttttattttattttactttttgtatgtg gatatccaatttccccaccaccattcattgaaaagactgtccttttcctatcgaatggtcttggcacccttgtaaaacat aatttgaccatatatgtgagggtttatttctgggctctctattctattctattctattctattctattctattctattct attctattctattctattctattggtccctatgtctttctttattctagtaccaccattttgctcatcataactttgtag taagttttgaagtcaggaatcgtaagacctccagctttgttcattttcaaggttgttttgattattcaaggtcccttgat agtccatatgaatttcaggatggatttttctatttctgcaaaaaaaaaaaaaaaaaaaaaaaaaatcattgaaattttta aacagattgcattaaatctgtagattgttttgggtagtattgacatttaacaacattaaatcttccaatcaatgaactag gctatttttatttattttttctgtttctttgagctacttttgtagttttcagtgtataagtttttgctacctggttaggt atacttctaagtattttctactttttgatgctattgcacattgaatcgttttcttaatttggtggtagcggggattgtgc attgttagtacataaaaatgcaactcattttttgtgtgttgattttgtatcctgcagctttaacaaattcatgttagttc taacagacttattctatgaatcattagggttttctacataaaagatcatgtcacctacaaacagagataattttactcca ccccttcccgttgcaatgccttttatgtctttttcttgcctaattgttctggctaagacttccactaccatgttgaatag aagtggtgaaagtagacatccttgtcttgttccaatcttagagccaaagctttcagtctttcacggcctgaaagactttg taatatgttctcaaggttaaagaacttcagaagttttctaagcaagagaccattttattaacttagttggcagcaattct gagagattagaatgaaaagatagaggataagaagtatctggcaggtataatatattgagtgtgctgaatatacttttagt tttgtataggtgttaaaaaatggcaaaggaggccgggcgtggtggctcacgcctgtaatcccagcactttgggaggccga ggcgggcagatcatgaggtcaggagatcgagaccatcctggctaaaacagtgaaaccctatctctactaaaaatacaaaa aactcgctgggcatggtggtggacacctgtagtcccagctactcgggaggctgaggcaggagaatggtgtgaacctggaa ggtggagcttgcagtgagccgagatcacgccactgcactccagcctgggcgacagagagagactccgtctcaaaagaaaa aaaaaatggcaaaggaaagaatgaaaaataaagcaaggtcccagaagaggccaaaaatcttaatcaaaattgactgaaca ttacggaatgaaatggtttttcctttactccaattaacgacttcacaagaagattccatcctcgtttataagattaaccc aaaaccagcacttaaaaccagaagccttgaaaggatggagtttggggacccttctcatgtctattcccagaagggggtct tcttctggggtcctgtcccctaaagagctaggcaaaaagtatgcttgccacatctgttgaaagatagaaagttggtctaa aaatacatgagagggaactgaaacatttcagagaaggcaagactcagaagtaagaaaccaaaagaggaaggtaaaattct agttacaaagaaaagaggaatggaaattaaattgtcttacagagaaaatccagaactgccccctcttcccttactactcc atcaaaaaaggggaaaaatagtcaatgggaaagttttgagaaaaatagatctctgcattcttctggttgagaattcagac aacttgaactagagagctgggtaatttcttgactaaaggtgtgttagatctgaaagggtttttcttaaaattgtctgtgt tcatccctcccatcttagagaggaacacaggataagagacctctggagctcccccagggtcaccgagctaataggatcag agacaaagctacaaagtcattttctgacatctctccagggctctttttttctggaccccccatatcaacatgatgtattt attacattggattagcaactctccttgagctttcctcagtaccaggtttacatctcagtctgtgggtctcagagaaagta cccaatcagcagcaacattacctggaaactcatcagaagtgcccctcctcagccccaccccagatctatgcaatcagaaa ctctggaaatgcaggccagtcctaacaagcccaccagggaattctggtgcactaaggtttgagatccactgatcaaagaa ataatattccttttcttcattataatagcatgaataataactaacatgtatttcacaatttacaaaagagctttatgctc ttgttaaatttgagggtagtcttctcaaaatctctgtgaggctagaaagtcagatattgaaacacctgttttatgggttc aaagataggttcaaaagagagtaaatgattgttggggtggcaggtccagagagggcaggatcaaaactgcaattgagtct tctgccttataaaccagcatagcttccccaaggcacgtcacttctcgataaaatggtgacaactagagtgtcctttcaga tcattcttagaagcatggagtgctaggtcaattgtgtaattgatgaggaaataataatactaagaactcccatcttctac gtccttatatacaatcctgtcaggtagaagctgagtctcagagagaacaagttgccctcccaggaccaccaggtaagctc ggcatagctgtgcttagaatgtaggctgtctggcttctgggcttgcctgcccagggaggctttgtgggttctacttggtc atccagatcacagaggggcagcactgactcctacccagtgctcttgactgtacatctaatactttctactaagaaaaccc cttctctttagaccaatggttttcaaatcttggtgtgcattggaatcacctggaaagcttgttaaaacacagattgtccc accccaagagtttctgattctgtaggctggggtggggacccatgaaagtgcatttctaataaggtcccaagtgatgctga tgccaccagtgtgtggacaaccctttgagtggtgaagctctggacaccctaatttgcaaggctaatcaggcatatgtggc aaatgaatacgaactgaaattctgactccaatatcttcactgatattcctaatccatagcatacacacagtcccattcgt ttcccttttagcttttaatctacatttatcctttcttcctctgccactgccttctctccagttagctcaaaccaggtaac acataaccgcctcctaactcatccgcccagttggtttctttggctttaatctagacttcttatctccaccagatttgcct taccaaagcaccaatttcttaaggcagggttagaattaaaaatcttctgttcctcctcattgcctaaaactcctaaactt atgattcaaggtcttccatgaccttcatggaccagtctaacgttttagcctgtcctaagtgacatgcctccaccacatac ttcatgctttccactttctttctccatgtctttgttcatgcatttccatttcttctacctgcgatgtcctccttcgccat ctctgtagatttaaaaatcctacagggctcatctcaaatgccctttccttcatgaagcctttcatgaaatccccatcgag aggttttccctcctctcagctctccaaagcacagatgtctgcgtttgtggctattatcttacgttgttttgtattaaaat ttctccagctttacacatttgtcatcctcttaaggacaaacatcttattatggtcaatgtgaagctatagaggataattt aatgaaatattccaagggctagtcattacacatgactgatttatctctgtaaactcatccacactcatccacctgatttt gattggccaagttaatgaatcagagaggaaaagatggtaaaaatataataaaaatctcctaggtagtctcacatcccaca gagccccaggtaatgaaatgaggccctgagataatactttatgaacaataaaactccgggttctattgacagtgaagcaa gacctgagagagaaggctaaattcccttgtgtctagctgccacaatcttctgagaataatggcctttcttcccgtctgcc ttctgaatcataggcaaatttttctctttggtgatccctaatacagaaaggggaagtcaaataaaatatatacaaggaga aggattctgggagacagagtttcttgattcccttctgcatgctcctcctcaaaagcctttatgagcttaccttacattta aattcttttaaacaaggcattatgtggtctggtcttttccagctccacacaccttcacactacattccccccagctaatt ctgctctgggaacactgaccttcttttagttctttgaacacattgatttctggtcaagatgactcagtaacttcaacctt tgttgtgcccttggtgctgtgaagatatagatatatattaaccactgcacaccagaaatcagaaatagcacaacagagaa taaagtcattgagccatcttctgagctccaaaagacaaattttctccaaaaagacaaattcaggctctaaaacaatacct taaggaaccagaagtggaatagaaaattaaggtggtaagcagggctaaaccacatgcctgttgagcccaggtttggaaga agacaatggcaggtaggaatgtggtttctgatgggtaataggtactgttttcatttactttctgttgcttataacagaat atctgaaactgggtgctttataaagaaaaggaatttatgtcttgcagttagggaaactgagaagtcaaaagttgagggct gcaattgacaagtgccttcttgctggtggggatactctgaagagtcttgaggtggtatcgggcataccactctcagtgag gggactgagcatactaggtcaggtctttcttcctccttttataaagctatcagtcccactcttatgataacccattaatc cattaactgattagccaattaatccatgaatggattaattcattcatgagggcagagccttcctgacccaaacacctctt aaagactccacctctcaatactgccacatgggggattaaatttcagcatgagtttttgatgagacaaatattccaatgat agcagttattaaaagtacatgcttgagagaaggggattggagtcagcctcagtgcttaaactcaaaagctaggatgaggc tctaacactcctgaaagaaggagttgctgctggctccttaccagggctatatcttttacagagcaggagacctaaagagg caggaggacccggacatcgtttggaaaccaagcactaaaacaggccatctgttatacccccaatatcctctcaggacaag tgttttgaaccactcacacaaggactagtctgggcaagtgggctagatgaagaaaccacaaaatagctaagtggggagag aaagaccaaaaatactattttattcaaaatgaaaatacaatccaaaattccatgattcatgaagaaatcaaatggtatgt gttaggtggttcttgcattgctatagagaaatacctgagattgggtaatttataaagaaaagaagtttaattggctcata attctgcaggcttcacaggaagcatggtgctggcatctgctcagcttctggagaggccccaagaagatttgctcaaggca gaaggttaagggagagctggcacatcacatggtgagaaaggaagctagagagagagtgcagggtgaggtgccacaagtta ccacagccagatctcttgagaactcacttactttcatgaggacagcaccaagccataaggtgtagggagccaaagtccca tgggacatgaccaactcagcattccactggaggctatatgatcaaacagcaaactgtttatcacgaatgcaggatgtgag caaactcacaactggtcctgccaacagaaggtttgttggaggcaatcactccctggtgcctgaggtaatctactgcaaca tctagagaatgcagtcttgcaagcctactctggacagggcagctggcaccttattccatcccccttctcactatcttttt ttgcctaataaatacagagggctgtgtaaagctcagggcccttgtccactagaggcaagttgccccctgaccccttcttc caaatatactcttttgtctcttgtcttttattctcacatttgccccctttgttcagttccactaggtccgtgcgggttat atactggtgccctgagcagcaacagaatcaggctctcaacaagtgtcatccgaacatgggactttgaggacatgaacgaa gaaggtctgctggagcagaggaacagaaattgacaaggtgaacagggaccctgggacgagtctgccagcagcggatataa ggtcagttacctaaagaggtactgatcagtgccctaaagagatactgggagcagtgctttaaagaagtactgggaatggg aaattttctgaatcagggtaacaaggggaagaatttgtctattaaagaaaaacattatgtgcagttgcttaaagttgtat tggaacagtctggagcttaggttaatttgcagacactaactatcacatgcgtccgtgtgaagagagtccaccaacaggct ttgtgtgggcaataaagctttttaatcaccttggtgcaggtgggctgagtccaaaaaaggagtcagcaaagggagataga ggtggggcagttttataggatttgggtaggtagtggaaagttacagttaaaagtggttatctcttgtgggcagaggcagg ggtcacaaggtgctgggtggggaaatcatgagactctttttctgggacaggagtgtcacaaggtcaattgatcagttggg gtggggcaggaacaaatcgcaatggtggaatgtcatcacttaaggcaggaactgactatttcacttcttttgtggttctt ca^'gttgtttcgggccatctggatgtatagtgcagctcacaggggatatgatggcttaggttgggctcagagacctgacat tcctatctttttatattaataagaaaaacaaaacaaaatagtggttaagtgttggggcagcaaaaattttttggggtggt atgtagagataaggggcaatgtttctcagggctgcttcaagcacgatcacggtggtgtgggaatctagagtgggagagat taagctgaagaaaaattttggggaaaggggtgatattctggggttgttagaaggagcatttgtcatatagaatgatgatg gcctggatgtggttttgtatgaattgagaaactaaacggaagacacaaggtccaaataagagaaggagaaaaacaggcat taaaggattaagaattgggaggacacaggacatccaattagagagtgcccaagggggtccagtgtaattatttgcctgga caatgagttttggggctctattaggttgtcatataccaggccagattgatttaggtaaaaacaacactcttcatttaaaa tatacagagtcctccttttttagcagtgagtaagttgagacctattcctgtcttcttatattaataagtaaaataaagca aaatagaggtgaagtgttggtgtcatgaggggaacaggaagcagttcggtcctatttgcaaattgattttgggggggtaa agaaaactagtgtacctttgcctgtccaattaataagtagacacatgtagatggaggagccacagaggaagaagagaact ttgtaaggcaaaactggaaatgtaaagggaaaagatgagagggagcaccaaaagaggtgtcttgcacccagactcaggga tctagtgagagcagcagctgttagaggttgtaatggggattaatggggctactgggtagagggggaggttcaacttttat ggtgtatgagaaagcgcatagtgtctacaagcaacctttcattgctattcataggattgggtataagtaaacaagaaggg ggggctaggaggagagtctgaagaacaaggggaaggtagccaaggatggagtgaaatgtagggcaaatgtcttaaaggaa atgagaggttctaagaggagggctagtggcttgtaacccacatggaagaggttacgaaaggatgatagaatggaatgagc ctgtgaggctggaaggaggaattttccttggtccaagaaccatttgccttgtgtgggaagagtttgataggtggaagttt cagtgggagggtaggcgggagtgactgatgagaaggagaaaaactggccataagggacagaagttggaatgctagctgct cctttagctaccttatcagcataagctttgccctgagtgatgggatctgatgccttttgatggcgcttgcagtgaatgac cctagcttccttggaagtagagcagctttaagaagagtttttatgaagaaggcattaataatggaggaccctcgtatagt gaggaaacctctttcaggccatataacagaatggaggtggagaatatggaaggcatatttagagtcagtataaatactga cacacaatccttttgcaagagtgagggctcgagttaaggcaatgagttcggcttgctgagagggagtggagtggggcaga gtggtagcctcaatgatagatgtgaaagatactatagcgtagcctgcctttgctggtgagtggtgattaggcctagtgga actgccatcaataaaccaagtgtgatcagagtgaggaacaggaaagaaggaaatatgggaaaatggagtgaatgctaggt ggatcagagagatacagtcatggggatcaggtgtggtatcaggaataatgtgggaggccagattgaagtccaggccagga acaatggtaattgtgggagactcaacaaagagtgagttcaactgaaggagccgggggagggggagagcggcagaaagtat atgcatcaggtgtgaggaagaaaatacattttgaaagttatgagaactgtagagagtgagttgatcatagtttgtgattt tgagggcctttaaaagtattaaagcagtggcagctgccacacacagacatgagagccagcctaaaacagtaaggtcaatc tgtttagacagaaaggctgcagggcactgtccaagctcttgtgtaaggattctgaccgcacagccttgtactttggctgt gtgtaatgaaaagggttgggatgagttagggagagctagtgtgggagtagcttctagggctgtttttaaggaacataaag aggagtggggaaaggatttaggatctatggggtcagctaggtttccttttgtgagtttatgtaatggtttagtcaggatg gcaaaaccaggtatccaaaggtgaaagtacccaaccatgtctaggaaggaaaggatttgttgctttgtagaagggattgg ggtttgggagattagccggacacagatcaggagggagagcacttgtatttttatgaagaattatgccgataggtaacgga tgaggaagaaatttgggctttggagggggatacacgatattcccttgagaatagatgttggaggagcaggagggtgtcct gttgggaagattcataggaggggctataaagtagaaggccatcaaaatattgaataaggtgacaagcagatggacagaaa agtaaattatgagaaagggcttgactgaagtaatggaggctgtccctgaagccttgtggcagtacagcccaggtaagttg ctgagactgatgggtgtcagggtcagtccaagtgtaagtgaagagaggctggggtgaagagtgcaaaggaatagtaaaga aagcatcttcaagatccagaacagaataatgggttgtggagggaggtattgaggataggagagtatatgggtttggcacc acagagtggataggcaagacaatttggttgataagctgaagatcctggacaggctttagtcccttcaaagcctgttgtgg gatgggatactggcattgagcaggataagggtaattaggttttaatgggatggtagggttgcgtgatcggtcaccaagga gggagtagaggtatcccatacttgtgggttaagatagggagtcaggaggggaggttgtgaaggaggctttgaactgggga aaagggtggcaatgaggtgtggctgtagcccaggaatagtcagggaagcagataatttagttaaaatgtctcaatttaat aagggagctgggcaggtgggaataactaaaaaggagtgcataaaagaatgttgtccaagttggcaccagagttggggagt tttaagaggtttagcagcctgaccatcaataaccacaacagttatggaggcaagggaaacaggcccttgaaaggaaagta atatggagtgggtagcctccatattgattaagaaagggacagacttaccctccactgtaagagttacccaaagtgtctgt gatgatccaggaggcttctgaggtgatcaggcagtgtcagtcttcagctgctaagctgagaagatctgggaaggagtcag tcagagagccctgggccagagttccaggggctctgggagtggctgacgggcaagttggacagtccgatttccaatgcggt cccacacagatgggatacagtttaggaggaatcctgggctgtaggcattccttggcccagtggccagatttctagcactt gaagcaagatcctggaggaatgcctgaccacagtggtttaggtgttttgaagttcttgtgtgctggagatgtggctgagg tttttctcacagcagaggcaagtaattgcaactcagaaatacattgccacttggctgtctcttctctattattgtacacc ttgaaggtgaggttaattaagtcctgttgtggggtttgagggccataatctaatttttgaagcttttttaatgttgggag tggattgggtaataaaatgcatattgagagtaagacagccttctggcccctctgaacctagggcagtaaaatgtctaaga gttgttgccaaagggaccatggactgggctgcgttttcatatttgatgaaaaaaaaagagcctaaatgctaactaatttg ggagaggtcagataaagtaaaaggaacattaatcttgactatgccttcagctcttgccacctctctaagaggaaattgtt gggcaagtggaggagtgctagtcgtggaatgaaaccataagctggactgggtgtgaggaggggaggtgatagaaggatta cagcgtaggggagtagaggctgaggaagaattgggacctggctcagcctggtgaggagtggcctggtgaggagcagcctg gggaggaggagagaggttagatgggttcgtagaaaagaaggattcaaaggactcggagcttggtgaggagactgaaggaa cagacaggagagaaagaagaaagatttgggacaagtcgcattgggagcagagactaggaagggagtgatgtgtaaagaat gcctggacatcaggcacctcagaccatttgcccattttatgacaaaaattatctaagtcttgtagggtggagaaatcaaa agtgccattttctggccatttggaacaattatcgagtttgtattggggccaaatggtgttgcagaagaaaataagatgct taggttttaggtcaggtgagagttgaagaggttttaggttttttagaacacaggctaaggcagaagaaggaggaatggag ggtggaaggctgcccataataaaaaggtaagtttagagaaaagagaggatagagacacagagagagggggtggtggtact catcagccaggggaggtggtacttgccaccaaggtgatggatcaaggcagtcatccccacggtgatcagacacctctgaa atgtgggtgaataatcaggcaggtgtccctgcagtgattagacaccaaggggagactgtcttcccgagtccgtgaccggt gctggagttttgagttcacagataaaacacatctcctctgtctctaccagaaagggaaaggaactgaaattaaggaaggg agagattgaagggtggagagatagcaagagagttggaaaagagaataaaaagaggccacttactcaatttaaaattggtg agatgttccttgggctgatctgaggacccaaggttgtaggtggatctcctcacggaatgagggtgaggacaggggactgg tctccagaaggagttcccgagtcctggatcttcagcaccaaatgtcatgtgcatccatgtgaagagagtccaccaacagg ctttgtgttatcaataaagctttttaatcaccttggtgcaggtgggctgagtctgaaaaaggagtcagcaaagagagata ggggtgggtcagttttataagatttgggtaggtagtggaaagttacagttagaggtggttatctcttgagggcagaggtg ggggtcacaaggtgctgggtggggaaatcctgagacttatcatccagggaaggagtgtcacaaggtcgattgatcagttg gggtggggcaggaacaaatcgcatggtggaatgtcatcagttaaggcaggaactcactatttcacttcttttgtggttct tcagtttcttcaggccatctggatgtacacgtgaaggttacggggatatatgatggcttagcttgggctcagaggcctga cactaacctcctgcagaagccacaaaaggttattacacataaaccatggtttccacaggcaggcactcttgatgtggaaa attgggatagagcaggattaaaacaagctcatcaaaaaggtcttaaagttgattcttcagttttctccacttggagttta gttcatactgtacttctgccattatctccttattattctgcggaacagcaggctgaatctaaaaattggaaagaatttgt tgtcctactcacagctccaattgaatataaaaaacaggagagggaggataaaaattggcctataccgcctcctccagatg cagaaacatctgtaccatctccttcagtggcagaaatagagatcccagtacaaagaattttatgctctgctgtcatagct ggagagcccttaggaccttgtgcttttcctatttctgtaaggcctgatccaaataatccacagcagtttattcatgaaca ctctccactagaatttaagttgttgaaggaattaaaaactagtgtggtcaataatggagtacaaagccaatggttcctgg aggaaggaatgctagacatagaactttgggagcaagtggggagaaatcttaaacaacaccaggcacaaaggcatcaggtc ccagtaaaatcttttatgttaggggctttgagtagagcagccctggttgttacacacaaaagagcctaaaaagggaaagg aggaggaaatgtcacctgccttatcacctccccttccctcagtgccaatatcactgggccaaaataacaaagaggaaatg gaggtcttacctaagcttcctcctccaatagataggaagaaggacagaggatacgctacagctatcagtccctgtcttaa gcaggcagcattagaaggagagctcttagccgggtgcagtggctcatgcctataatcccagcactttgggaggccgaggc aggcagatcatgaggtcaggagatccagaccatcctagctaacatggtgaaaccccgtctccactaaaaatacaaaaaat tagccaggcatgttggtgggcacctgtagccccagctacttgggaggctgaggcaggagaatggcatgaacccaggaggt ggagcttggagctttcagtgacctgagattgcaccactgcactacagcctgggcaacagagcaagactccatctaaaaaa agaagaagaaggagagctcttaacctgctcagtaatgcaaaatcggcaaggcaatcaggtgtatgtttataaaaagataa gaaaaaggcattagaagccaaaaccacgtggccaagcaggcagtgggcaggagaaaatgctcagaggcagaaaagctcac agcgacaaagccaacaaggtctgcccaggacggcagcatccctctggcaaaggagcaagggagcagcacagacacaggca aagcctaaacaagtacaatgtggccacctcccaggacctgcaccactgccctctggctctgtgggcagcccattgcaaaa tttcatgtgttacatctcaggctatgattctctgctaagatgtaagtaaaatgtaagaatttgaaaagcatcttttctaa taatggccactattgtcatctctctcctatccctgatgtagctttccaaattcaatttaagtaaaacagtaacctttgaa gggaaagagattacagagggcccatgaattagttgaagagtaattaaaagctaggcatgtaaaaccacacattacgcttt aaagaagaaatttaaacctaattaaatgatatttgttaaattagaaggtaaaaatgttgtgccctgttgggaacaggccc ccaaatctggccataaactggccccaaaacaggccataaacaaaatctctgcagcaccatgacatgtttgtgatggccat gatgcccaccttgaaggttgttggtttactggaatgagggcaaggaacacctggcccacccagggcagaaaattccttaa aggcattcccaaaccactaatgatagcatgagcaatctgtgccttaaggacatgttcctgctgcagacagctagccagag cccatccctttgttttggcccatccctttgtttcccataaggaatgctttcagttaatctatgatctatagaaacgatgc ttatcactggcttgctgtcaataaatatgggagtaaaactctgttcagggctttcagctcagaaagccataagccccctg atttcccacttcccaccctttatttctgtgtgtgtgtcttgaattcctctagcgcctctgggttatggtctccacaacca cgctggtcttggcagtgcccttctcagaaagtgaaaaagagttgtatgtaagtgtagtgaaaacataagcatgaatcact gtcttaacccactgattagatagtctttgatttgtacttgctaaaagagtcctaaattgagttcctcagctagtgagtca ctgttttcaagactgtttgccagattgaagtccataaacttggtcagcccgaaaactcaattacaagatctaagctattc tgcctgtggctttaagcacatggttaaagtatattatttaagtctctccttctagatatgctttcagattttctttttaa acttcttgttactta ttcagctttccatattgataattaatgcagtcaattgctcagttatgactgtgatatcatcagg attcctttaagtaaaaggcaattcaaagcggtattgcactcccccatacctaatgctttaacactgtttactgatgggtc tggtaaacatggaaaagctgcagtctagtagagaccacataattcaatcactcgatctgagttcactagcactcagagag ctaaggttactctgtttatttattaaagaatttttacaaccttaagctcactctggactttccagccttatgtggcaaat gtagccatcaatttatggggtcaagacttacttacagcatgggatatgaggcttacaaatgagactttgataacccagga ttttaaatgttgaagaacacgggatatcagagtgaaaaaggtttagggaaaattctgacaagggaaaattctaacctgat atcaataactggaaagacaggttaaaccctgcaaggggatacattgacattttttcttcctcacttgctcttttctgctg tctgaatatgggcatgagggcaagagtcattttagaccaccaagtgaccttgaggatagaagccttatactagaggtggt gggaaagaaaaaacagaaggactcataaagaaaaaaataataaacctcagtattaagatggaaaaattcccccaattggt ctataggttgaacttcatctctattaaatttcagctatgtttttgcagaatttgatatgctgatcataaaatttatatga aaatgcaagagacacagaatagtcaaaactttgaaaagaagaaagttggaggacttacacttgttgattttaaggctttt tacaaagctataataatcaagacaatgtgttactgacataatgatagacatattgatcaatatagacaatggatgaatgg agtagaattgacagtctagaaataaaaccttatatatatggtcaatttatttctttatgtattctgtcatccagaataca taaagaacaccttcaactcaataacaacaataccaacaagggtgccaagaccaatcaatggaggaaataatagtcttttc aagaaattttgctgagacaactaagtatttatatgcaaaataatgagtttgaatggctaccatatacaaaaattaactca aatggactatattaggtcagtgcaacagtaattgcagtttaccaccattacttgttttttttttttggtttttttttttg agacagagtcttgctctgtcacccagaccagagtgcagtggcatgatctcagctcactgcaagctccacttcctgagttc acgccattctccttcctcagcctcctgagtagctgggactacaggcatctgggtaatttttttgtatttttagtggagat ggagtttcaccatgttagccaggatggtctcaatctcttgacctcgtgatctgcccacctcagcctcccaaagtgctggg attacaggcatgagccaccacgcctggcctaccattacttttaatggcaaaaatgcagttacttttgcaccaccctaata gaactaaatgtaagagctaaaactacaaaactgttagaagaaagcataggagcaaatcttaatgacatgagagttggcaa ttgttttttagatatgacaccaaaagcatcaaggacaaaagaaaaaaatggataaattggacttcctccaaattaagaga acttttgtcctgcaagcaatactattaagaaagtgaaaagacaagtcacaaaatgggagaacatttttgcacataatata tttaataataggctgacatccagaatacataaatacctacaactcaataccaaaaagacagcccaatttaaaaatgggcc aaggatatgaataaacatttctctaaagaagatacaaaaatggtcaatatgcacatgaaaagatgctcaatatcaatatc tattaggaaaatacaaattaaaacacaaaatataaaacacaagatatcaatttacactcaccaggatggctgttatcaaa aagacagataacaagtattggcaaggatttggggaaattgtaaccttcat cattgctggtaggaatataaaatttgcag caggtttggaaaacagtttagcagtttctcaaaaagcctgggcatggtggctcatgcctacaatcccagtgctttaggga gctgaggtgagaggattgcttgagcccaggagttggagaccagcctgagtaacacagtgagacctcttttctaccaaaaa gaagagagttaaacatagggtaccatataagccagcaatccatctcctagatatgtacccaagaaagttgaaaacatata ctgacacaaaaacttacatatgaatcttcatattagccttataataatagccaaaaagtagaaacaacccaaatacccat caactaattaaaatatggtgtatctatacatattatttggccataaaaggaagtactgatacatgtcataacacaaatga accttggaagcactatgatctctgtattagtcagctcttgtattgctataaagaactacctgagactgggtaacttataa agaaaaaggcttaattgagtcacagttccacaggctgcacagggatcatggcccaggagacctcaggaaacacagttatg atggaaggaagagagtgaaggaggaggtgctacatacttttaaaccaccagatcttgtgagaagtcactcactatcatga gaacagcaagggagaagtccacccccatgatccagtcagccccagccaggccccaactccaatattggggattacaattc cacatgagatttgggtggggacactaatccaaacaatatcattctgccccagcccctcccaaatcctgtgtccttctcac attggaagatacaatcatcccttctcaacagtttcatttcagtattaactcaaaaatccaaagtctcatctgagacaaga caagtcccttccacctatgagcctataagatcaaaaagaagttagttacttccaagatacaatggaggtacaggcattgg gcaaatatatccattccaaaagggaaaaattagccaaaacaaaggggccacaggccccacgcaagtccaaaatcaagcag ggaaatcattaaatcttaaagcttcaaaatgatatcctttgactccatgtctcacatccaggccacaccaatgcaaggag tgtgctcccaaggccttgggcagctctaccctgttgctctacagggtatagcccccatggctgctttcacaggctggcat tgagtgcctccagcttttccaggtacacagtgcaagctgttagtggatctaccattctagggtctggaagattgtggccc tcttctcatagctccagtagacagtgccccagtggggaatctgtatgggggctgcaaccccacatttctcctctgcactg cccaatagaggttctccatgagggctccattcctgtagcatacttctacctggacatccaggtgttttcatacatcctct aaaatctaggtaggggctcccaagccttaactcttgccctctgcacatccgcaggcttaataccacatggaaaccaccaa tgcttatggcttgcaccctatgaagcagtagtctgagacatatctgggcccttttggccatggctgggatgcagggaaca gtgtcctgaagtggcacagggcagcggggccatgggcctggcccatgaaaccttctttcctcctaggcctccagacctgt gatgggagggtctgcctcgacggtctctagaatgtgtttgaggcatattcctcattgtcttggctattaatatttggctc ctctttacttatgcaaatttctacagcctgattaattcctttccaaaaaaatggggttttcttttctactacatggtcag gtcacaaattttccaaacttttacgcttccctttgaaatgtaagttccagttgcaggtcatttctttgatcacaaatata agcatatatttgtagaatcagccaggccacatcttgaatgttttgctgcttagaaactgcttccaccagataccctaaat cattgctatcaggttcaaaattctacatatctctagggcaagggcacaatgcctccaagacctttgctaatgcataagaa aattgacctttgctccagttcccaataagttccccatcttcatctgaggtctccttagcctggacttcattgtccatatc agtatcagcattttcatcacaataatttaactagtctctaagaagttccaaactttcccttatcttcctatcttcttctg agccctccaaactgctccaacctctgcccattacccgggttccaaagctgcttccacattttcggtatctttatagcaat gctccattcctgataccaattttctgtattagtctcttctcgcactcctgtaaagaactacctgagactgggtaatttat aaagaaaagaggtttaattgactcacagttccacaagctgtataggaagcatggttcagaaggccacaggaaacttacaa tcatggaggaaggcgaagagaaagaaggcacgtcttacgtggctggagtaggaggaagagagtgaagggggaggtgttac acacttttaaacaaccagatcttgtgagaactcactcactatcatgagaacagcaagggagaggtctgcctccatgatcc aatcacctcctaccaggctcctcctccaacattggggattatgatttgacatgagatttgggtagggacacaactccaaa ccatatcaatcccatttatatgaaatgtccacaatagataaatctatagagacataaaatagattggtgcttgcctagtg ctggacgtgacaggagggtgtgagtaaaagaggcaatggagtgataggtacagggtttctttttggggtgatgaaaatat tataaaattagattgtggttatagttgtataactcttgaatatcctaaaaatatattgaattttccatttccattttaaa tgggtgaatcttatggtatgtgaattatatctcaataaaactgcaaaaaatgcacaatttgcaattgcaaaaatatggaa ccagtccaaatgcccatcaatgagtggataaaggaactgtggtatatatatatatatatatatatatatatatatatata tatatatatatatatatacacacacacacacaccatggaatactactcagccataaaagggaataaaacaatggcattct cagcaacctggatggaattggagaccattattctaagtgaaataactcagtaatggaaaaccgaatatcatacattctca ctcataagtgggagctaagctatgaggatgcaaaggcataagaatgatataatggactttgggaactcagggaaagggtg agagaggggtgaggaataaaaggctacccattgggtacagtgtacactgttcaagtgatggctgcaccaaaatctcagaa atcaccactaaagaacttatttacataaccaaataccacctgtttctcaaaaacctattgaaattaattaatttttaaaa actgctgaaatcaatagtgaaaggatggactattcaataatgacacagttaattgaatatcatattttaaaaattagatc cttacctcacactataacataacaataaattccaggtgaattatagaccaaatatgaaaagcaaaattttaatattttag aagacaatttttatgaccttaagttagaaaatgatttttaaaaacaggatgcaaaaacactaatcataaagagatatttt aggccaagcatggtggctcacacctgtaatcctagtactttgggaagctgaggcaggtggatcacttgaggtcaggagtt caagacaagcctggccaatagggtgaaacatgtctctactaaaaatacaaaaattagctggaaatcgctcgaacccagga ggcagaggttgcagtgagctgagattgtgccactgcactccagcctgggtgacagagagagactccacctcaaaaaaata aataaataaaaataaagagagattttaataaggtgcattaaaataaaaaactatccatcaaagacaccatgaataaagtt aaaataggccacaatgagaatatatttgccatgaattttttctttttttttgagatggagtcttgctctgtcacccaggc tggagtgcagtggtgcaatctcggcttactgcaaacttcacctcccaggttcaagcaattctcctgcctcagcctcctga gtagctgggattacaggtgtgtgccaccatgcctggctaatttttgtattttttgtagacacggggtttcaccatgttgg tcaggctgagctcaaacccctgacctcgtgatccaccttcctcagcctcccaaagtgctgggattacaggcatgagccac cgtgcctggcctaccatgaatatttttttaaaggtagcatccagaattaataatcttctccaacaaatttcattagtagt cagggaactgcaaattaaaatcaaagtaaaatactactttccactcattagactaaaatccattcaagtctgataatacc tagtactgagttggagtaatagaaactgctaatgggacagttagttggtcatcactttggagagaaattagtcagtatct agtaaaagttagtgatacaccttccattttcatctgttctgtgctgctaccaaagaatacctgagactaggtaatttata aataatagaaatgtatttctaatggttctagaggctgagaagtccaagattgaagggccagcctctgcagagagccttct tgctgtgtcatgccatggcagaagggcaaagagagggcaagagagagcaaaagcaaattcacagcatcaatcccttttat aatcagcattactctattaatgagggcaagaccctcatggcctaatcacctctaaaaggtcacacctcttaatactattg caatggtaattaagtttctaatacatactttttgggagacattttcaaactatagcacctaccctatagcccaacatttc tactcctaggagtatgccctagagaaattctgcataaatatctaaagagaggccattgttgcattgttaggtactggaaa attggaatcaattactatgtctaccagcagcagaagatggctttttaaaagttttggtttattcatgaaatggaatattg cataaagtatgctccatctcaccagatgaaaacatttttcactaggactatttcaaaagtagtcttatcactgggcttct ctattatgcataaaaattttaagtgaacatgttctttgacctagtactcctacttttaggaatttgcccaaaagggacaa ttatactactgggataaatctttgaatcataaagtaagttgtaaatggtacaagcagtatgtcttatttttatttaaagc acattaacaatattacacatatagtaaaaaataaataaataaaacatgtgaataataaacacccaatttagaacaagtgt tgacagtggagagggaaagagagagaaagaaggagaaatggggagtgggagcgggtacacaaggaaattttagttgcagc tccaaatttttactttttacacaatgaagcgaatatggcaaaataagatttgttaaagttgggcagcaggtacacagata ttctatcattatcctttgaatatttctgtagatttaagttgtccattaaaaaaataaaatacacacataatttttaagat tagttttttctatttcctggccttcgcatgcactgttaactttacctggaattctttatgcagtaattaagagcaaaggt gtagagcaagactgcttgagcttggatcccagcactgagttgatttagggagaataacttaatctcttaatcccaagaga aaatatgatataatagttttgagctcataaagttttcataagcattaaatgtgacctatatatgtaaagcaatctaacag tgcctatagtatttataagtgtctgcattaccaaattcatcattatcatggcatgtcatgtcaccatccactacattacc atcactgtcaccatcatcatcatcaccaccaccatcatcattaactccctttgtctagtcaattcatatttgttcttcgt attttagatacctgttaaaatattttttcaaagatgtctactctgattcttcagtacaaatttgatttaataagatccta tcattttgtccaaatacttataaaaatttgtagttctatatttaatgtgttttgtttgtttaacatctctctcctacatt gtgttaagttttttaaagagaaggtaagggttaaagagagacatagagagagaaagagagacagagagagagagagagcg gttctacagcaatacaggtatattagaaaaacctgcaaaggtggggaccagcttaatgccagagccccccactgcttata ggctggggtacttataggtctgggggtacttataggcctgggtgggtggggtctgagcagtatggcttgctgcccaagaa gatgttgataagacgttcccatgatgaggcagtttggtccttgcttccatagagtgtgatgcttcttgcactttttccca gcagaatgtggtagggatgttccttcaggtgggcctttgcctggcagggtatgataaggatgttcctgtgccttggaatc aggtagttagacaggatgtttctcacagcctgaacccccatggaatgtttcactttgaccagggtctgcgaaatagcagg gggcttacaaaatggtgtagtttggactaacaccttggaacacaaaagtttcttggggccaaggctggcgtattagtctg ttttcatgctgctagtaaagacatacctgagactgggtaatttataaagagaaaagaggtttaatggactcacaattcca catggctggaggcctcacaatcatgagggaggcaaaggaggagcaaaggcacgtcttacatggtggtaggcaagagaacg tgtgcaggggaactgccctttataaaaccatcagatcttgtgatacttattcactatcaaaagaacagcacgggaaaaat ctgcctccatgattcaattacctcccaccagattcctcccatgacatgtggtaattatgggaactacaattcaagatgaa atttgggtggggacacagtcaaaccatatcagctgggtatgttttattcacctttttatacccattgtcatgtcttctgg acaaacaatggatgtaaaatggtatagactcctgagtactcatttgttgaatgacaaatctatgaaccatttgaccagta tgcagcagccattaaaattatgtttatgaataatttacagcatggaaaaatttggggttgctagtagaaaaacaaaaagg tacaaaaggatatatataataagcctacaatgccatataaacaatactaacagcaaaaacaaacctataaattgggggaa gatggggcagatagaagtaacctaaaatactaacatgttgttttggggtcatgaaattataaatgattatgcacccctta atttttactttctatgtttgatttttctatggtaaatgcatttttattgaggtggaattcacataacatgaaatgaaaaa tttagtggcatttattatattcacaatattgtacaaccactagctctacttccaaaacattttcatcactccaaaataaa accttgtacccattaagcagttactccccattatttcctctcttagctcctagcaaccaccaacctgctttctgtctcta gggatttatttattctggatattccataaaaatggaggcacaatatgtaccttttatgtctggcttctttcaccaagcat gtttttgaggctaatccacattgcagcatgtatcagtacttcatttctttttatgaataactgtatacagaccacaattt gt atccattttttggtttatggacatttgggttgtttccatctctcaactattgtgaatagtgctgctatgtatatttg tgtacaagaatttggttacctattttcaattcttttatgtatatatctaagatgaaattgcagggtt tatgctaatcct atgtttagcatttttttttaggaaccattaaactgttttccaaatctgatgccccattttatattcctactagcaatgta agcaagttccaatttctccatatcctcaacaacacttgttattttctatttttgttatagccattctaatgagtgtaaag tgatatatcattgtggttttctttgcattttccttatgaacattgatgttgagtaccttttcatgtactttttggtcatt tatatatcatctttggagaaatgcctcttcgtgtatgttttgcccattttaaaactagattgtctttgttgttgacatgc atgcattctttaaatattctgcatactaggcccttatcagatatatgatttgcaaatgttttttctcattttactggctg tcttttcactttattgataatgtcctttgatgcccaaaagttgtttattttgatgaagcatatttatcaatttatttctt ttattgctcatgcttttgatgtcacctctaagaatttataaccaaatcagaggtaatgaaggtttacccctctattttct tctaagagttttatagttttgactcatttacttaggtcgctgattcatttttagttaatttttgcatatgatgtgaggaa gaggtccaactttactcatttgcatgtggatattcagctgtgccagcaccatttgtgaagagtctatcatctcctcattt aataatagtattgacacctttgttgaaagtcaattgataataaatgtatgagtttatttctggaatctaaattctattcc attgatctacatgtctatccttgtatcagtatcacactatcttgattactgtagatttgtagtaagttttgaaactagaa agtgtgagtactgcaatattcttctttttcttttttaaagattgtcagggcctcttgcaatttaatagggatatgaggat tgacttttctattctacaaaattaaaattttgttagagattgcattgacactgtaggtagctttcagtaacattgccatc tcaacaattttaagtattctaatacatgaatatgagctttctttctctttatttaggtcttctttaatttctttcagcag tgttttgtagttttggggtacaagtctttcacctttaaattttggtgaaatttattcctaggtattgcatttttttatgc tattgtaaataaaattattttctcaatttcctgttggatgttcattgcaggtgtatagaaactcaactgattctttgtgt tgatcttatgctgagaccagctcagttggggagaccctaacctagaagcactagaggaattaaagacacaaacacagaaa tatagaggtgtaaagtgggaaatcaggcgtctcacagccttcagagctgagagcttcaaacagagatttacccacatatt tattaacagcaagccagtcattagcattgtttctatagatattagattaactaaaagtatcccttatgggaaacgaaggg aagggctgaaataaagggatgggttgggctagttatctgcagcaggagcatgtccttaagtcatagatcactcatgctat tgtttgtggtttaagaatgcctttaagcggttttctgccctgtgtgggacaggtgttccttgccctcattccggtaagcc cacaaccttccagcgtgggcattatggccatcatgaacatgtcacggtgctgcagcggtttttatggccagttttggggc cagtttatggccagattttggggggcctgttcccaacaatcttataccttgcaattttgctgaatttgcttgttaacttt gatagtttttttgaggattatttgggattttctacatatcatgtcatctgtgaataaagatagttttgcttctttctttc tcatttggatgccttttatttccttttcttgcctaatttccctggctagaacttccagtatgatgttgaataaccatggt gaaatgggcattcttgtctttttcctgatgttagagagaaatttttcagtctttaaccattgagtataatgttagctgtg ggttttttacaaatatcttttatcatgttgaggaagttccttcctactcctacttcttggagtgtttttgatataaaggg tatttaatttgtcaaatgctttttctgtgtcagttgagattatcatgtgagattttttttccttcattctattagtgttg atgttacattggttgattttttatgttgtactacatttgcattctttatataaatttcacttggtcatggtgtataaccc ttttaatatgccattggatttagtttgctagtattttgtttagagtttttgcatctatattcataagcaatatcagtcca caggttttttgtggtttatttgtctggctttgctataatggtaatgctgtcttcttagaatgaatgagggagtgttttct cctctttcattttttaaacgtttgagaaggagtgatattaatttttctttaaatgtttggtagaacttaccagtgaagcc gtctggttcttaacatttttctgtgttgggaggtttctgattaccaatttgatctctttaatttttacagatcttttcag attttctatttcttcttgagtaactttttagcaatttatgtattttagaaatttgttcatttaatctaggttatttaatt tattggtgtgcattttttcatagtattatcttataatcttttaatttttgtaaagttgataatgtccccaccttacctga tcttagttatttgtgtcttctctgtattctttttgtcttcttcttctgtcttagcatagctaaaggtttgtcaactttgt tgatcttttaaagagtcaacttttgctttcagcatgcattactttttaaatagaaatatatacacctaagttgcattaca aaggagttgtcctccacacacttattctttcccaccatcagaggtttatggtccccgcaaaagtcaccatcagttgggct caactccaatcagtcatggtaggtcagggtccatctcattgtctccatcactcatgcccacccagggtaagtctaatcat gttcaccaatcagaacctctgccacatcagctctgtgggtttcctctcatgccatctgtaccaacaatgagcacagtctg ggtttcctgatgttttctatagcatggtgcccctccctgggacacctcagaagccacaatgatattcattaaacttcttc ctgcaagtactccctctattgctccttctactcaccaagcttagtgtcagggaatatgctggtggggagtatgaatctta gcttctcactcccagactcggctcccaacctgctgttgccaagtcttggggacatctataaatgccttctaaatacctgt cttggcctatccccagccacagattcctccctagagcaggctacctctgaggcatctatactgagatcttaatcacagag acatttaaaacatctaggctacaaaagaattcctactatagggttcaaatgaatttctttccgtcacttgagacagcttt ttagcaagtacatgtattaaagattctgatttccccttttttctcctacagtttgtttggcctaaaggtatgacatctaa tctgctgcatttacactctaagtcaaaattaccattttgttcttttaatttctatttctaatcatacattcttgtctact cctggttcatctggagacaaagttgaacttagaagatggaggagaaattcttatctgccctctgctagttgacacttcct ttccaagaatcatttgcagttgctgggctttcttgctgtgactctatgccctgttgtgttactttttcatttgtgacaaa aacagtggtaatagtttgcttcatttttattatgaagacttgaccaggataggtaggaacataattactgctttttctgt gggcatcatattggtccagatcatgtttaaccagaattgaagatgtaaaatcctagaactcactaatctattttagtagg tcacaggaagcatgcaaaccataaaaaccgcaatgaaccaaaagcatctgtgttgacaagaggcaagaatttctctattt 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caagtggtattgtttattcttttgatccttctagctgttaaggaagaaaaaaataattttttcctcaatgctcataagtt cttggaatggacccctgtaacaaaagacagattaacacgagaaaagtttattaacgtacatattttatacgtacatagga gctatccagggaatgaataattcttaaaaaggtgactttgaattccagctcatatagcatcttcaacaaagttcagtaac attttagagatatgacaagacaaagaaaatgaactttgagcctctagggacagtgacttgtaggaaggcaaaaggaataa atggaggtaaaggctggttagtaatacttgttaatgaagattcctctggtgccatctccaggtccacaaggatttaaatt tgtcttcagtggtgaacctttgttcaccctggcagaaggtgtggaggggggtgcagatccgttttgtctttgtaagtcta tatcctgcttttagacaaataaagggagggaaaagagctttccttcatctgcttcttaattgccttcagctcaacaatcc ttatgcaaaagaggtacattttagggtgtcaaattctggtctcccacaaagcatagggatgacagaccacctcaccatcc ctgttgcttcttttaagcctgctcacccctccaaaaatattttcattctatactgtctcttcaaaatctcagcggagggt gccctctgttatcctgccctctgtgtcagtataagccaaaggtttgaatcctggctctgcaactatctacctctgtgcct ctccttgtttatgaaattacagggctggagacaaagatcacaatgtgaagacaaaattggagagcggtcctaatcagcca gagcaaaatttctggctcttgctcttccccatcctgggttgaatcataggaacaggtggcaagatgccagggtcaggaga ttccagaagtggcagcaagctcagtgttaccaggtcagggatgacctgtcttattattgaaatctcagagatatgctcca attccggcccagagacacattgagagacaactggggaacttgctatgttcctgaacaggcaatgagctgtcttccaagaa aaaacctgagacccttcaagtctcaggtcttacttagcacatataccaggtcttacacaggacacatggttacaactgac tgaaatctgggctgggtgtaggagctcacacctgtaatcccagcccttcaggaggctgaggcaggcagattgcctgagcc caggagttcgagaccagcccgggcaacatgacaaaaccccatctctacaaaaaatagtcaggcatggtggcatgcacctg tagtctcagctacttgggaggctgagatgagaggattgcttgaggttgagactgcagtgaagcatgatcatgccaccgca ctccagcctaggcaacagagcaagatcttgtcgcaaaagaaagcaaaaacacaacataacacaacaacaacaacaacaac aacaacagcaaaaaagccaacttcttgaaatctggaaaggacacctggactgccctgagcatttgattgttgttggctct agcagtggatgcatccttcaacctctggcactctgcagggctcagactgttctgttctgtttgttacctgtggagtgcct gccagaccctgctctagctgctttaggtccatttaccctcatagacccccagtcttgttattcatatttcatatttggga aatggaaacttagaaacttgccaagtccacagcatgagatcctgcctccggtgtctgctggattccagaaagtgccaggg gccaacttagatgacaccatgttctctgcacaatcttaggaatgctcctagtctgatgtccccattgcaaaatttacatt 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gagcactcaattaatgaccacagttgtgattctttaggcagatgcatttttttccaactttgatcagaggtcttatttag cttctccagatttcaagaatctggctcagtgatatgaaatacaagacttgtgaaaagtgtcaattgcaagagaaatggaa ggataaagtatacaggtgggtggaaaagaaattcacagtcactgccagaaaaaaaattcttgagaatcaagtcctgatga tgttagggcttatagttcttattataaagagttttatgtactcattcagtgaacatttattggtgcctcctttagccagg tactatcataagagctgaaaataaaagcataatccagtccttgatcttgaggaacatgctgtgtgtagcagataacataa taagtgcttatctagatgcatgcagtgttatgtgataagagtaatatgacagaggatacagattaggcttcacagagaag ggggatttgagcaggaggtattgaagggtgaatagaagctcaccaatcattttgggcagaggggcaaggacctgcaaaac cactgaagcatgaaggaaatggtgagtttagggaaaatgaagagaagatggctgtgactgaagcacaggatttgggattg gagaagggactggaggtgaggctgagaagaggcaaactcagaaaagatgttgtgctgggcagtctggacattatctttga agcccaccacatataagtcatagggctactggaggttttaagctaaaagtgactattcaatttcaacttaagagaagata ggttgagagggaacatggcttgagatgagccatgagcaaaggaaagactacaacaaagccaggagtgaggagtgtgtgaa gcaagaaagtgacagttgaaagcagtgcagaggggatgaatctgagaggcatctatgaggtggaactcaaatgacatgat 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gaggtcaagagaccgagaccatcctggccaacatggtgaatccccatctctactaaaaatacaaaaattagcggggcatg gtggtgcacgcctatagtcccatctactcaggaggctgaggcaggagaatcacttgaacccaggaggtggaggttgcagt gagctgagatcatggccactgcactatagcctggagacacagcgagactccgtctccaaaaaaaaaaaaaaagaaggcag aaggtgaatagttcaagggtgggtttaggactcagtgataataggattctgcctggcttctcatggttctctaggtcttc cattcatggcaccatgccctcactaggcatgctgccagagcaggaggggcaggtggagggttctcttgtgtctgtcttat cagggaagaagagctttctcagaagcccccagcagactcccttttcatattatggtccagcaatgagtcacagacctatg caccacctgcaaaggagccagagaaaacaaacgcccagcgcttttagcctgaaaatgagaatctggtttgctggggaaga taaagggtgtcggaaaatggctgttgggtaaatcattgatgtctgccactaggaatgaaaggcaaatcaggaactggcac acatgctttcagggagatggctgcaagggagagggcaaagactgggaagttgcttatgtggtgccagactatttggaaga tcatggattgcggtgtttgtgttgtgtggtcatcattttgttctttgtttacagaacagagaaagtggattgaacaagga cgcatttccccagtacatccacaacatgctgtccacatctcgttctcggtttatcagaaataccaacgagagcggtgaag aagtcaccaccttttttgattatgattacggtgctccctgtcataaatttgacgtgaagcaaattggggcccaactcctg cctccgctctactcgctggtgttcatctttggttttgtgggcaacatgctggtcgtcctcatcttaataaactgcaaaaa gctgaagtgcttgactgacatttacctgctcaacctggccatctctgatctgctttttcttattactctcccattgtggg ctcactctgctgcaaatgagtgggtctttgggaatgcaatgtgcaaattattcacagggctgtatcacatcggttatttt ggcggaatcttcttcatcatcctcctgacaatcgatagatacctggctattgtccatgctgtgtttgctttaaaagccag gacggtcacctttggggtggtgacaagtgtgatcacctggttggtggctgtgtttgcttctgtcccaggaatcatcttta ctaaatgccagaaagaagattctgtttatgtctgtggcccttattttccacgaggatggaataatttccacacaataatg aggaacattttggggctggtcctgccgctgctcatcatggtcatctgctactcgggaatcctgaaaaccctgcttcggtg tcgaaacgagaagaagaggcatagggcagtgagagtcatcttcaccatcatgattgtttactttctcttctggactccct ataacattgtcattctcctgaacaccttccaggaattcttcggcctgagtaactgtgaaagcaccagtcaactggaccaa gccacgcaggtgacagagactcttgggatgactcactgctgcatcaatcccatcatctatgccttcgttggggagaagtt cagaaggtatctctcggtgttcttccgaaagcacatcaccaagcgcttctgcaaacaatgtccagttttctacagggaga cagtggatggagtgacttcaacaaacacgccttccactggggagcaggaagtctcggctggtttataaaacgaggagcag tttgattgttgtttataaagggagataacaatctgtatataacaacaaacttcaagggtttgttgaacaatagaaacctg taaagcaggtgcccaggaacctcagggctgtgtgtactaatacagactatgtcacccaatgcatatccaacatgtgctca gggaataatccagaaaaactgtgggtagagactttgactctccagaaagctcatctcagctcctgaaaaatgcctcatta ccttgtgctaatcctctttttctagtcttcataatttcttcactcaatctctgattctgtcaatgtcttgaaatcaaggg ccagctggaggtgaagaagagaatgtgacaggcacagatgaatgggagtgagggatagtggggtcagggctgagaggaga aggagggagacatgagcatggctgagcctggacaaagacaaaggtgagcaaagggctcacgcattcagccaggagatgat actggtccttagccccatctgccacgtgtatttaaccttgaagggttcaccaggtcagggagagtttgggaactgcaata acctgggagttttggtggagtccgatgattctcttttgcataagtgcatgacatatttttgctttattacagtttatcta tggcacccatgcaccttacatttgaaatctatgaaatatcatgctccattgttcagatgcttcttaggccacatccccct gtctaaaaattcagaaaatttttgtttataaaagatgcattatctatgatatgctaatatatgtatatgcaatatatata ggctcttgcttgatctctccaggaggtagtgattatgagaagggggtggagaatgatgagttccttcaccaggagcaaag gacggggatcgtgtggaaccactgcagaactatttccggaatcaactaagtggagagagccaggaaggctgcatcagaac ccagtaaagcttcttgtctggatctgagctggtttgttttgtgcttgcttttccctgccttgccactcccctcactcttc tcttttccccacagcctttttcacatagctcttggctgtaggattgccccactccaaaaaccagtgtgtggaggtccagg agtgagaccaggaaagaatgtgaaagtgactacacaaggactcctcgatggtcgtggaaaaggaaagtcaattggcagag cccctgaagccagtcttcaggacaaagaaggagcctagagacagaaatgacagatctctgctttggaaatcacacgtctg gcttcacagatgtgtgattcacagtgtgaatcttggtgtctacgttaccaggcaggaaggctgagaggagagagactcca gctgggttggaaaacagtattttccaaactaccttccagttcctcatttttgaatacaggcatagagttcagactttttt taaatagtaaaaataaaattaaagctgaaaactgcaacttgtaaatgtggtaaagagttagtttgagttactatcatgtc aaacgtgaaaatgctgtattagtcacagagataattctagctttgagcttaagaattttgagcaggtggtatgtttggga gactgctgagtcaacccaatagttgttgattggcaggagttggaagtgtgtgatctgtgggcacattagcctatgtgcat gcagcatctaagtaatgatgtcgtttgaatcacagtatacgctccatcgctgtcatctcagctggatctccattctctca ggcttgctgccaaaagccttttgtgttttgttttgtatcattatgaagtcatgcgtttaatcacattcgagtgtttcagt gcttcgcagatgtccttgatgctcatattgttccctattttgccagtgggaactcctaaatcaaattggcttctaatcaa 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tgggaggggtagagaaggtcctgtgcacagtcacagtgcgctgtgcagagcaggaacagaggcatctgtgaaaagtgctg agagcctggaggacagagtgactaatgcaatgacagtcttgcatcataggaataacagccacagcaggattttattgctg ccaaagaaactgccatttaaaaattgccagccatccgggaggctgaggcaggagaatgg'catgaatccaggaggcggagc ttgcagtgagccgagatcgggccactgcactccagcctgggcaacagagccagactccatctcaaaaaaaaaaaaaaatg ccagccatctctctttctaaagtggaatcctcaagtctcgtttattctggggacatttgagtaggctgttcgagttaagc aggtggaagttgatgatccctca catcattctgagggatgagtgtctgaagactttttggtaaggaagggtcttggcat agcccaccccatgccacctcccttgatctgtgatatccccagcagctggggaggttggagcattttgcaaagaggccccg aagcctccagaaagtaaaccttcaagagcccatccttccttcctcttttgtttttgctcattatgaaaacttccctgaca aattgaaaaggcttcaggtgagattagcccacaggaaaaaccaccaagggccacccagaggggccacactgtgacagaag gagtatgggctggtgagctgacctctggaagacagtgcatgaattgaggagaagagattggttccaggcatgggaggaat gaggctggaaatttcttcagacattgccacttcggcactctgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtg tgtgtgtgtgtgtaaacagagtcctgtaatgcaaggtccggccttggcagccccagcctggagccacagtgagatgtgag ctgagggttatgctgggaaaaacctctccctcccagcacctgaaaggctctgcaggcccagcagctcagcaagcaagggt aagggcatggactaacatcttatttcatactatcccttataacacatcctaatgtaatcagctcacaatatgaaattatt tcatttctctccagtcattgtttcaatggggccttagggttgactggattctggaggtccctgcctagaggagggggtgc attctgtccctatgtcccctcctgctccatcctccacagcacgtgcctagtggtctaccttgtggggaattcttgtacct ccctcttctaggcatggactagcattgagaagtgggagaggagtgttaggaaaaagggcaaatatagacataccttgtct tattgtgctttacagatattgtttttgttgttgttgttgttgtttacaaattgaaggtttgtggcaaccctgcctcgagc aagtctattggtgctgtttttccaacagcatgtgcttgttttacatctctgtgtcacattttggtaattctcccaatatt tcaaactttgtcattatttctatatctgttatggtaatctgtgatcagtgatctttgatgtcactattgtagttgttttg gggcaccatgaagtgcacccatgtaagatggcaaacaatcaataaatgttgtgtgtgttctgactgctccatggactgcc tgttcctgagacacaataatgtatatataacaattatatatatatatatttataacaattatatatatatatattttttt tttttttttgaggcagagtcgcactctgattgcccaggctggagtgcaatgatgtgatttcagctcactgcaacctctgc ctccccaggctcaggtgattctcccacttcagcctcccaagctgggactacaggtgtgcaccatcacacccggctaattt tttttttgtatttttaggagagacagggttttgccatgttgcccaggctggccttaaactcctagactcaaacaatccac ctgcctcagcttcccaaagggctgggattacaggcatgagccactgtgcccagcccaagacacaataatattgaaattaa gccaattaataaccctacaatggcctctaagtgttcaagtgaagggaaaagtcccacgtctctcactttaaatcaaaatc tagaaatgattaagcttagtaaggaggacatattgaaagtcaaggccaaaagctcacctctgcaccagttagccaaattg cgacttcacaggaaaagttcttgaaggatatttaagctctactccagggaacatgcaaatgaagagaaaacaaagcagcc atattgctaatatggagaaagtttgagtggtctggagaaaagatccaaccagccacaacatttccttaagtcaaagccta atccagagcaagactctaactctcttcaatgctatgaaggcggagagaggtgaggaagctgcagaagaaaagtttgaagc tagcggaggttggtttgtgaggtttaatgaaagacaacatctccataacataaaaatgcaagatgaagcagcaagtgcaa agggagaagctgtggcaagttatccagaaaatctagataagataattgatgaaagtgtctacacgaaacaacagattttc agtgtagacaaaacagtcttatgttggaagaagatgccatccaggactttcacagctagagaggagatgtcaaggcaagc tgcaaagctccacaggacaggctgactctctttttagaggtgaatgcagctgatgactttaagttgaagtaaatgttcat ttactattttgtaaatcctggtgtcattaagaattatgcgaaatctactctatctgtgctccataaatggaacaataaag cctggatgacaacacatctgtttacagcatggtttactgaatatttcaagcccactattgagaactattgctcagaaaaa aagattcctttcaaaatattactgctctgcaccatgtcgatcaagagctgtgttggagatgtacgagaatattcatgttg ttttcatccctgctaacacaaacatccattctgcagtccatggaccaagactttcaagtcttattaagaaatatatttca taaggctattaagaaatagctatatatatatatatatatagccttatatagtttatatagctaccattgatagtgattcc attgatggatctgagcaaagcaaattgaaaagcttctggaaagtagtcattattctagatgccattaggaacatttgtaa ttcatgggaggaggtcaaaataccaacattaacaggagtgtgaaagacattgattccaacccccatagatgactttcagg ggttcacgtcttcagtggaggaagttgctgtagatgtggtggaaacagcaagagaactagaactagaagtggagcctgaa gttgtgactgaattgccgcactctcatgatcaaacttgaacagatgaagagttgcttcttacatatgagcagtgaaagtg gtctcttgagatggaatctcctcctggtgaagatgctgtgaacacggttaaaatgacaacaatcgatttagaatattaca taaatttagttaataaagcagtggcagggtttgagaggattgactccaattttgaaagaagtgggtaaaatgctatcaaa tagcatcacatggtatggagaaatcttttgtgaagggaagagtcgaccaaggtggcaaattgcattgtcatcttatttta agaaattgccacagccacccccagctttagcaaccaccaccctgatcagtaagcagccatcaacatcaaaacaagaccgc catcctcttcagcaaaaacactatgacttgctgaaggctcagatgatggttagcatttttagcaatacaatatttttaat taaggtatgcacattggtttttctgacataatactattgcatacttaatagactacagtataggataaacacaactttta tatgcactgggaaaccaaaaaggttatttttgagatatttgctttactgtggtggtctgaagctgaactcacaatctcac caaggtgtgcctgaacctctttagctaactggccactgccacagtccactctgtgttggtcaagatgccccagagtggca ggcacactgtgtggtcacatccaagggcctagatatggtgggggctccaaatggatctagatatgtgagatctctctttg atttgacttcttccaacccaccattttctgggtgctgggctcatctcacccagaaagtaggacccaatgtgacagttcct gcccagttccctcctgtggtagccacttgacccaggggcactcttgatccttgcagcctcacttacacaccctatctcta cccctattaactctctccaatccccactccccctgctcagcttgtctgctgcccagtgggggccccacccatgctggcct ctccttttgcaagtccccattcctcatatggtttcttcagagcccctttctttggctttgaggagagatgccctcactcg cttccccaccaatcctgcccacttctacaatccattcattatcctaattgcctccgtatacagactggagtgagaggagt tgatgtgatgggtgtggatacagggctggtgctgtcatcttctagtaagccctgggagaggtgtctgagcccaggtgtca gtggttttctttggaactgtgagtgcataacacttctttgccttcagccttaggccatagttgctagttctgggacaacc agaaaagccctacataatctcgtgttatgtgcagagctgagtatagagctccaggtatgatctgactcacttaagatcac agtgagtctattgtattgttgaactgttagcttagacatctgttactgtacctacatggcactagcctcacgcctagaca ccgatctgaaagaaatcccctaaatgcatagagaagacttctcagctgagctaaggggctcccaccaggtttgagcctat ctaatgaatccatgaggtagacagcctgcacatgtccacttggtttgatgaattgcacaaatccctatgggggatgtggt tcatgggctgggaagtgggttaccctgggaaaggtctacaggacagaggcagggatggagacaacagcatggtgagttcc caacccacccacgatgataggtgtctgaggcagaaggtaaagaggctgtcacctggtgggtgtcataagactcaagtgtc attgttgaggcacatgggtaacaaagcgtggcactggatgggggtagattcttcctatttctgtgaggatcagggggact ccctggctctcctgctaaaggtggctctagggacaggaagagtgtacttcttgacagggatgtcagagcactgatggtga caatcagtgtgacactgctcacatgactgaacaaccgagaagagcccgactgtctactgaacaacgggaagagcccgact gtcaatgacggagctctgttaaatatagttaaggctattttgttgaatgaatgaagccagacaggaaagaggacagtatc tttaatccatttatagaagttaaagacaggcttatttaatctctatgaagacagagtggcccttacctctgggtggagca aaaggcaccttctgaagtgatagggatgttccttatcatcttgatccggagtggtagttacatgcatgtatgcatatcaa aactcaccaagctgtaccactaagtgtgttcttcctcaataaaaataataaagaactacacttataaagaattttttaat aatataggaaaatgtctacactataatctttagctaaaaaaaaaaaaaaagaagccgcctacagaatggtatatgcatga gaacaattaatcgaaaagtgcatgggaaaagtcaggattgaaacatcatgttttaaaagacattgttttgatactgtgag aatgtacctaagtttttccttttttctgtttttcccaattttatacaatgagcatgtgttggttttataattagacattt tgtttgtttggtttggttttgagacacagcttgctgtcacccaggttggagtgcaatggcccaatcttggttcactgcaa cctccatctcctgggttcaagagattctcccacttcagcctcctgagtagctgggactataggggcgcaccaccacatcc agctaattttgtgtatttttagtagagatggggtttcaccatgctggccaggttggtctcaaactcctgacctcaagtta tccactcgccttggcttcccaaagtgctgggattataggcatgagccaccgcacttggcctagacatttgtttttaaaaa taaaagattcatttgctctttttacagcccgtctcactgttgactgatattgaccaggagtcaactcaggccccagggat tttcacaacagctgctgtatggcagggtttctgctcactgtgctcatgtagttggcccttgcacccaaagtgaataatta acattctccccatcctgttgacgatgctctgaaaatatggtccagaaatggtgtgagcaaggagacagcaaagcaatgct tggaacataggtgcagtgactagacatggggcagctgtttaaagacaaaaaggccccaaaaaggagggatggcacgaaac accctccaatatgggcatggagtctagagtgacaaagtgatcaaaagttcatttcctatggggtgtccgaatgtacttaa taataaaaagagaacaagagccatgcaaactgagagggacaaagtagaaagagtagcagacaccaagcaactaagtcaca gcatgataagctgctagcttgttgtcattattgtatccagaacaacatttcatttaaatgctgaagaatttcccatgggt ccccactttcttgtgaatccttgggctgaacccccctgtcctgagtggttactagaacacacctctggaccagaaacaca aaagtggagtaacacacactgcaaagctgtgcttccttgtttcagcctgtgaatcctcaccttgtttcccatctagccta tatttttcaaactaacttggccatagaatcatgtagtatttagggtggaagctgccccaggtctagcacgtcatttaaca gatgaggaaatggaagcttgggcagtggaagtatcttgccgaggtcacacagcaagtcagcagcacagcgtgtgtgactc cgagcctgctccgctagcccacattgccctctgggggtgagtatgtcttcacatcctccaataccctaatgacagacaaa cagaacatggcaaagcctcagctctgcatggtgaaagtaagaaccagcaattgccacaaacagaaatacagtgttggtcc ggcagcctccgggggttctgcacaagtggattaccagtgaatacaaggctatctatctttcgaaaaaccaacgttgtatt tatgctattttctataaaattttatattaatttatttgttacctatttttgaactctttcaaaagcacactttatatttc cctgcttaaacagtcccccgagggtgggtgcccaaaaggctctacacttgttatcattccctctccaccacaggcatatt gagtaagtttgtatttgggtttttttaaaacctccactctacagttaagaaaactaaggcacagagcttcaataatttgg tcagagccaagtagcagtaatgaagctggaggttaaacccagcagcatgactgcagttcttaatcaatgccttttgaatt gcacatatgggatgaactagaacattttctcgatgattcgctgtccttgttatgattatgttactgagctctgttgt gc acagacatatgtccctatatggggcggggttgggggtgtcttgatcgctgggctatttctatactgttctggcttttccc aagcagtcatttctttctattctccaagcaccagcaattagctttaccttttcagcttctagtttgctgaaactaatctg ctatagacagagactccggtgaaccaattttattaggatttgatcaaataaactctctctgacaaaggactgctgaaaga gtaactaagagtttgatgtttactgagtgcatagtatgtgctagatgctggccgtggatgcctcatagaatcctcccaac aactcatgaaatgactactgtcattcagcccaatacccagacgagaaagctgagggtaagacaggtttcaagcttggcag tctgactacagaggccactggcttagcccctgggttagtctgcctctgtaggattgggggcacgtaattttgctgtttgg ggtctcatttgccttcttagagatcacaagccaaagctttttattctagagccaaggtcacggaagcccagagggcatct tgtggctcgggagtagctctctgctgtcttctcagctctgctgacaatacttgagattttcagatgtcaccaaccaccaa gagagcttgatatgactgtatatagtatagtcataaagaacctgaacttgaccatatacttatgtcatgtggaaaatttc tcatagcttcagatagattatatctggagtgaagaatcctgccacctatgtatctggcatagtgtgagtcctcataaatg cttactggtttgaagggcaacaaaatagtgaacagagtgaaaatccccactaagatcctgggtccagaaaaagatgggaa acctgtttagctcacccgtgagcccatagttaaaactctttagacaacaggttttttccgtttacagagaacaataatat tgggtggtgagcatctgtgtgggggttggggtgggataggggatacggggagagtggagaaaaagggggcacagggttaa tgtgaagtccaggatccccctctacatttaaagttggtttaagttggctttaattaatagcaactcttaagataatcaga attttcttaaccttttagccttactgttgaaaagccctgtgatcttgtacaaatcatttgcttcttggatagtaatttct tttactaaaatgtgggcttttgactagatgaatgtaaatgttcttctagctctgatatcctttattctttatattttcta acagattctgtgtagtgggatgagcagagaacaaaaacaaaataatccagtgagaaaagcccgtaaataaactttcagac cagagatctattctctagcttattttaagctcaacttaaaaggaagaactgttctctgattcttttcgccttcaatacac ttaatgatttaactccaccctccttcaaaagaaacagcatttcctacttttatactgtctatatgattgatttgcacagc tcatctggccagaagagctgagacatccgttcccctacaagaaactctccccggtaagtaacctctcagctgcttggcct gttagttagcttctgagatgagtaaaagactttacaggaaacccatagaagacatttggcaaacaccaagtgctcat ca attatcttaaaatataatctttaagataaggaaagggtcacagtttggaatgagtttcagacggttataacatcaaagat acaaaacatgattgtgagtgaaagactttaaagggagcaatagtattttaataactaacaatccttacctctcaaaagaa agatttgcagagagatgagtcttagctgaaatcttgaaatcttatcttctgctaaggagaactaaaccctctccagtgag atgccttctgaatatgtgcccacaagaagttgtgtctaagtctggttctcttttttctttttcctccagacaagagggaa gcctaaaaatggtcaaaattaatattaaattacaaacgccaaataaaattttcctctaatatatcagtttcatggcacag ttagtatataattctttatggttcaaaattaaaaatgagcttttctaggggcttctctcagctgcctagtctaaggtgca gggagtttgagactcacagggtttaataagagaaaattctcagctagagcagctgaacttaaatagactaggcaagacag ctggttataagactaaactacccagaatgcatgacattcatctgtggtggcagacgaaacattttttattatattatttc ttgggtatgtatgacaactcttaattgtggcaactcaaactacaaacacaaacttcacagaaaatgtgaggattttacaa ttggctgttgtcatctatgaccttccctgggacttgggcacccggccatttcactctgactacatcatgtcaccaaacat ctgatggtcttgccttttaattctctttttgaggactgagagggagggtagcatggtagttaagagtgcaggcttcccgc attcaaaatcggttgcttactagctgtgtggctttgagcaagttactcaccctctctgtgcttcaaggtccttgtctgca aaatgtgaaaaatatttcctgcctcataaggttgccctaaggattaaatgaatgaatgggtatgatgcttagaacagtga ttggcatccagtatgtgccctcgaggcctcttaattattactggcttgctcatagtgcatgttctttgtgggctaactct agcgtcaataaaaatgttaagactgagttgcagctgggcatggtggctcatgcctgtaatcccagcattctaggaggctg aggcaggaggatcgcttgagcccaggagttcgagaccagcctgggcaacatagtgtgatcttgtatctataaaaataaac aaaattagcttggtgtggtggcgcctgtagtccccagccacttggaggggtgaggtgagaggattgcttgagcccgggat gatccaggctgcagtgagccatgatcgtgccactgcactccagcctgggcgacagagtgagaccctgtctcacaacaaca acagcaacaaaaaggctgagctgcaccatgcttgacccagtttcttaaaattgttgtcaaagcttcattcactccatggt gctatagagcacaagattttatttggtgagatggtgctttcatgaattcccccaacagagccaagctctccatctagtgg acagggaagctagcagcaaaccttcccttcactacaaaacttcattgcttggccaaaaagagagttaattcaatgtagac atctatgtaggcaattaaaaacctattgatgtataaaacagtttgcattcatggagggcaactaaatacattctaggact ttataaaagatcactttttatttatgcacagggtggaacaagatggattatcaagtgtcaagtccaatctatgacatcaa ttattatacatcggagccctgccaaaaaatcaatgtgaagcaaatcgcagcccgcctcctgcctccgctctactcactgg tgttcatctttggttttgtgggcaacatgctggtcatcctcatcctgataaactgcaaaaggctgaagagcatgactgac a ctacctgctcaacctggccatctctgacctgtttttccttcttactgtccccttctgggctcactatgctgccgccca gtgggactttggaaatacaatgtgtcaactcttgacagggctctattttataggcttcttctctggaatcttcttcatca tcctcctgacaatcgataggtacctggctgtcgtccatgctgtgtttgctttaaaagccaggacggtcacctttggggtg gtgacaagtgtgatcacttgggtggtggctgtgtttgcgtctctcccaggaatcatctttaccagatctcaaaaagaagg tcttcattacacctgcagctctcattttccatacagtcagtatcaattctggaagaatttccagacattaaagatagtca tcttggggctggtcctgccgctgcttgtcatggtcatctgctactcgggaatcctaaaaactctgcttcggtgtcgaaat gagaagaagaggcacagggctgtgaggcttatcttcaccatcatgattgtttattttctcttctgggctccctacaacat tgtccttctcctgaacaccttccaggaattctttggcctgaataattgcagtagctctaacaggttggaccaagctatgc aggtgacagagactcttgggatgacgcactgctgcatcaaccccatcatctatgcctttgtcggggagaagttcagaaac tacctcttagtcttcttccaaaagcacattgccaaacgcttctgcaaatgctgttctattttccagcaagaggctcccga gcgagcaagctcagtttacacccgatccactggggagcaggaaatatctgtgggcttgtgacacggactcaagtgggctg gtgacccagtcagagttgtgcacatggcttagttttcatacacagcctgggctgggggtggggtgggagaggtctttttt aaaaggaagttactgttatagagggtctaagattcatccatttatttggcatctgtttaaagtagattagatcttttaag cccatcaattatagaaagccaaatcaaaatatgttgatgaaaaatagcaacctttttatctccccttcacatgcatcaag ttattgacaaactctcccttcactccgaaagttccttatgtatatttaaaagaaagcctcagagaattgctgattcttga gtttagtgatctgaacagaaataccaaaattatttcagaaatgtacaactttttacctagtacaaggcaacatataggtt gtaaatgtgtttaaaacaggtctttgtcttgctatggggagaaaagacatgaatatgattagtaaagaaatgacactttt catgtgtgatttcccctccaaggtatggttaataagtttcactgacttagaaccaggcgagagacttgtggcctgggaga gctggggaagcttcttaaatgagaaggaatttgagttggatcatctattgctggcaaagacagaagcctcactgcaagca ctgcatgggcaagcttggctgtagaaggagacagagctggttgggaagacatggggaggaaggacaaggctagatcatga agaaccttgacggcattgctccgtctaagtcatgagctgagcagggagatcctggttggtgttgcagaaggtttactctg tggccaaaggagggtcaggaaggatgagcatttagggcaaggagaccaccaacagccctcaggtcagggtgaggatggcc tctgctaagctcaaggcgtgaggatgggaaggagggaggtattcgtaaggatgggaaggagggaggtattcgtgcagcat atgaggatgcagagtcagcagaactggggtggatttggtttggaagtgagggtcagagaggagtcagagagaatccctag tcttcaagcagattggagaaacccttgaaaagacatcaagcacagaaggaggaggaggaggtttaggtcaagaagaagat ggattggtgtaaaaggatgggtctggtttgcagagcttgaacacagtctcacccagactccaggctgtctttcactgaat gcttctgacttcatagatttccttcccatcccagctgaaatactgaggggtctccaggaggagactagatttatgaatac acgaggtatgaggtctaggaacatacttcagctcacacatgagatctaggtgaggattgattacctagtagtcatttcat gggttgttgggaggattctatgaggcaaccacaggcagcatttagcacatactacacattcaataagcatcaaactctta gttactcattcagggatagcactgagcaaagcattgagcaaaggggtcccatagaggtgagggaagcctgaaaaactaag atgctgcctgcccagtgcacacaagtgtaggtatcattttctgcatttaaccgtcaataggcaaaggggggaagggacat attcatttggaaataagctgccttgagccttaaaacccacaaaagtacaatttaccagcctccgtatttcagactgaatg ggggtggggggggcgccttaggtacttattccagatgccttctccagacaaaccagaagcaacagaaaaaatcgtctctc cctccctttgaaatgaatataccccttagtgtttgggtatattcatttcaaagggagagagagaggtttttttctgttct ttctcatatgattgtgcacatacttgagactgttttgaatttgggggatggctaaaaccatcatagtacaggtaaggtga gggaatagtaagtggtgagaactactcagggaatgaaggtgtcagaataataagaggtgctactgactttctcagcctct gaatatgaacggtgagcattgtggctgtcagcaggaagcaacgaagggaaatgtctttccttttgctcttaagttgtgga gagtgcaacagtagcataggaccctaccctctgggccaagtcaaagacattctgacatcttagtatttgcatattcttat gtatgtgaaagttacaaattgcttgaaagaaaatatgcatctaataaaaaacaccttctaaaataattcattatattctt gctctttcagtcaagtgtacatttagagaatagcacataaaactgccagagcattttataagcagctgttttcttcctta gtgtgtgtgcatgtgtgtgtgatgtatacaaagagagagataattgtatttttgtattttcttttaaataatttttaaaa ttgacccttttcctgagacaaattgccagaatagtttgtatttagagatggtacctctaagagtaaggttgctggttgct gagcaattgacttgaaaacttttaaaattcaaattttaattccactactcaaaagaattgccatgttttaaaaaagagaa ttggtgccataagttagttgtctatgtttgaaaatgaagaagatatgcaacgtcatggcctggtcacttacccgcagccc tgagttgtaggcacatcatatgtgagaatgaggatgcttttctttcatttaaaatccctccccaaaacttggctctaatt gcagtcatgacaatcatgtacatttggatttatgtgcacgagtctcttaccctgagagaggacaggtgctacaggtggag gggacccgtctgggtcacgttcacattttgaacatgctggttttcagtcactgcacactcatctcccagcgcaggtcatg ggcagcagatgcaaaagctgcccgtggtcctatttggaggtgcatgaaatgagcagaagacagaatagcttgatctgact agaagggcagcttgtccctaccaagacttgaaggattgcctttcatctgttagggtaaaaggtagaatgaaccaaggaag ggcaggagggggctggggttagggtagaaggaaggggccatggagaagggagatccatcccataggaggaaggcagtgcg gcagggaggtttgaaggtatcagcttttgtggctgacatacatgcagtcatgtcaattgctcgtttttccttttccatct tattaaatgtcttccaatgttagcacgaagaaaagctatttgcagtgttgccagcctttccagagcccgtccccattacc tccccaggcccatgcctttactccttggagtttcaactcacgaccttcaggatctgactttattcaccaactctggggtg aacgtaccttctgtctccacccagaggtctctatcaaagaggagattgcatgccatggataaagtcaaagtagaggtgac tgtccttaggaagagtaatgtgaaaattcataaactgggattctgtttacattttgtactccaggggttcttagtttaaa tcgctctgaataaattaagatgcaatggcatttcaactgttatgattaaatttacaaatcatttattttctatcacgggg agagatagagctccaaatgcaaacataactgctcaagtgttaacacttataatgaaaacataagaattaccaccaactac cctgggggctagaagcagaaatgtgaaccagaaaacaaatcatgaactttcctttttttttttgagatggagtctcgctc tgttgcccaggctggagtgcaatggtgcgatctcggctcactgcaaccactgcctcccgggttcaagcaattctcctgcc tcagcctcctgagtagctgggactacaggcatgcaccaccacgcctgggtaattttttgtatttttagtagagacagggt ttcaccgtattagccaggatgctctcgatctcctgacctcgtgatctgcccgcctcggcctcccaccgaagtgctgggat tacaggcatgagccactgtgcccggccaacaaatcatgaactttctaactgcagttccttgtagcttgttaacacatcca cttacttattgtcagagtacgtggagattttccacaaccctcggggataaggctgaacagaagaggcaaaaacgtgaaaa catttcgatagctcctatactttgaaataaaattcactgtaaaagttgcttgtatttttccaaaacagagtcaaccctta atatttaagattctgtatacaaatacatatttttatataattaatatatattgtcatatgacatatatctttatattaat atgcatgcatataatatatatttccttcctaattttctataagcaattttacaagactgacttctatttgcctccttatt gttactacgtggtttgataatccgttttgtgtcattgtgattctgtcatgttttggggacttatttttgtttctctgggt ggtcactagtttttttaaagcattcatggaagagtgtgaatcttttacaagctaggaagccatggcaagccttgggtcat actgcccccgcgaggccacattggcaaaccagcaagggtgttcaacttccagacttggccatggagaagacatacgagga ggcttttcacattcagctctttaatgtttgtctctgccggcaccatcccagttgtgaataagaggtatttccacagcggc tcagggtaggtagtgcacagctcacattcatcatttctgaaaaccgagaggagtctccattcggggtacaggttgatgcc tgtcgtggaatgaaggttccaacacccagaccaatctctgcagtgtgctgctctcatgagcttgcaacaagatcagaaaa tgttttgtgactaagcatttttcatattgcataaaatgcttcaagctcctcccttgtttctctctataatcctgtatatc tgatgattgtgggtaccaagtgtttgaaataatcaaatgtgatttgatgttggtaaatttctttttttttttttttttac ttctattttttttattatactttaagttttagggtacatgtgcacattgtgcaggttagttacatatgtatacatgtgcc atgctggtgcactgcacccactaactcgtcatctagcattaggtatatctcccaatgctatccctcccccctccccccac cccaccacagtccccaaagtgtgatattccccttcctatgtccatgtgatctcattgttcaattcccacctatgagtgag aatatgcggtgtttggttttttgttcttgcgatagtttactgagaatgatggtttccaatttcatccatgtccctacaaa ggacatgaacatagcaaagacttggaaccaacccaaatgtccaacaatgatagactggattaagaaaatgtggcacatat acaccatggtaaatttctttatcattcgcactctcctttctctattattgttattgtaactgaaccgcagattagtcact cattgcttgcagaatccaattaacaagagcgaggtcagatataaagaaaatgatttattccaaacctccttcagggaaga ggtgcagcctcctgcctctaaatgcactgcttcgccaggcgtggtggctcacacctgtaatcccagcactttgggagacc gaggagggcagatcacttaaggtcaggagttcaagaccggcctggccaatatagtgaaacccctgcctctactaaaaata caaaaaattagccagacgtggtggcgggtgcttgtaatcccagctactcgggaggctgaggcaggagaatcgcttgaacc tgggaggtggaagttgcagtgagctgacatctagccactgcactccagcctgggtgacagagtgagactctgtctcaaaa taaataaataaataaataaataaataaatagtaaatgcactgctttgcttttggagcagaaagcaggcactttgaaaagg caggggaggaagtgagcaagggcagggggtctgcacactggcatggtgcctgatctatccaggcagttgaattggcactt tcataggcagaaataagttgaaaaagtggcctaaaactctctaggtgggagtggatagtgggcatgccttcaacctgcct ttctggagggtgagttccatggcaaccccctgaagggtgagagttccatggagatcatgctttggtctgtaaatcagctg ttaactctctagaaagttctgtcttggagcatatagttagatgaacttgccctgtaaagaatgtctggtgaaggggaagt aaaaggtgagatttgcatttctaaagggctaagtagaacgtggggtacaagaggaaaggagaaaagagaaaataatttaa aaaataattgtaacttattcccttttacttagaaaaaagggaatactcagttacattatcacctcgtttacatcaaaccc tcttatggaatcctatggtttgaaaacaaaaaggttgttgaggaccagtgagcccaacccctttgctttataaatgaaga gcattgcctgccctaagccccagagactctgatgtcgtgggtctggagtgggctccaacagcggcatgttttgatggtgc ttcccagtggcacgccagcgatgagcctttgagtagggaaagtaggagcactcgtgactcccttcacgatcagcacctgt gtgctaataaattcacaaaagccaacatattggagtcactcagggagttttacaaatagtgaggttaaatccaacctcaa atagttctgattcgatctgcctgcattgctgccctgtggttccccactgtagaagctccccaggtgattctaagtgtagc caagtctgagaaatactgcctaaagcctgttggactgacagcaagggctgttgtctgagcaagactttgcctggcctggg gtggcatgtgcaccaggaagagtctcaactttcataacagaacattccccaagctggtttttttaaagcatgtgaatcta gacttcattggcaataccaaagatctgtatttgaggctccaagtatttcactttcatttttggttttgggttatgttttc acccttcctttccaagtgaaaagtaaacagaagtgggatgtctggcgcccatgctgagcttggcaacttcaaattcaata gagaagaagtctcttgtatagaaaagggcctgtctgagatgtttctcaaataaatatagattttgcttatgtggctaaag gattcttctccccccatttccttatccctgcagtgagccatccttcttaactctttccatgaaagcattattcctgaaga actgggaactcatgccagccctgatcaggcaatgataattctgcagagaattagaatttagatttaaattgtcaactctt atacatcctggcatatggtttaaacacatgtacacacacacaaacacctcctactatttactgaagagcagatatctgat aacttaatctttttggttttgagtcaagacaattcctccttttgaaactgcataccgctgaatataataaaatgtaatta agattaaaaataagaaactaatgggagaatttcaatattgtctctgttcactttaaaattcctctacttaggtttactgc cattaccaaagactattcaaaaatcctttttaggagaatcctaatggtttcctgacatataatcaaataaggactctgtt gattggctaactcaatcttcctgtgccaaaaagcagagcccagcagagaagagggcagggacttgaaagtcagactgact cgagttccagccttggggctgtgggagcttgggcaagtgacttaacgtctctggctctcaggatctaaaaggatttccag tagtaatttggggtgttactgatacaggagctaaaaagaaattatttaggtggttagtgagggtcagagagtcctcggta agatttgccttttaacaaaaagcagccccaaaatcatttgtttgctaacaaagagaagcctgtaaaattgagctgcagac atagataagcaagctggaagcttgcacgggtgaatgccggcagctgtgccaataggaaaaggctatctgggggccaggca tgttcaacatggattctccatcttcccttttctttgtcaaccaagtgtacagtaaaggaacaggcaacatggcacgggcc aggtagagaacccttctgcataataaaagattagggtgagatggccagcttcttcccgtgctatgtaaatggcatacctg gtccaaccagtcttttgggccctgtgtaaatcagacaccgcctcctcaagttagtctataaaaccccatgcattttaccg tgaaactgggagatccactcggaaccccctcctgcacgagagaccttttctcttttgcctattacacttccgctcttaaa ctcactgctcatgtgttagcatccttgatttccttggcatgaggcaatgaaccttgtgtattaccccatacaaatgatgc tgcttcattactaatagcaacctgacagggttgtgttggggtataaattatctagaccagggagatccaatataattttt ttgtaatgacgggaatgctttgtatctgcatcatccaaaatggtagccaccaggccagggtgaaatgtggccagtgtgac tgaggaactgaatgttttccatgatttaatttaaatgtggccaatggctactgtaggagacagtgtgagtctggcatatt ataaataataaatattaatataatttgaactttggcatcagtgtttcctagatttgaattactatgcaagttgcttactg tttccaagcctcagctttctaatctgtaattggggctaataatagtatctgccttacaggtttgttcagaggataaatga gaaattgcatgttgagggcttaacacagtgcctggcacataaaagctctggtaacagttagccactttaataatttgcta ataatggctatttcttcttcagattaggatgtgctcccccaaacagtgcacttagacatagcgggcaatccagctcactc tctgcagtgagagagaagcactggccgaccagagtcagccaggggctcatgggtatgaaatcaacagcatgattttgtaa gtaatggatggaaagggcctcacaactttatggcactgtgttcaatttgcttggtcttctgtagctccttttgaaagcct tttagggtggattaacctgctaccaataattctggtcagatgtagactccatagctcaaagcaaactgagagagtgaggg cagcaggccaattccccaccccttccttctggactctgacagaagcttacactcaaggaagagcaagtaggaattaacgt gttaagagctaggtaagcaaaacccaatgagaagttctggcaaagccccatgggcaggggtggcttaggcacaggaaaca agtaggatttcataccacgcgcctcagtctacttccggggccctcatcctcagctgtgcctatgcaaaggagagcaacca a aaaccccaccgccactctcctactgtggaggccagggatggccaggggtaagagagggatgggaagtgtttcctccag ccgtcctctgagaaggagaggaaactgggcagagcttctgtcctccttcaagcagaaacagaaacaaaagaaacccctaa gggggttcttacttcccctctagttcagttgtgcactaaccatctgcagctcaacattcagcattcattcattgattcag caaacattgaaggagggccagctatgtgccagatgccaactcatgccatgaaagagagtccctgtccttatgaaattcac tatttagagagaaaagcaagcaaaaaggcaaagtttgaaaagtactgttgaagtggcatcattgtctggggtgaatacct gaggtttgtggtctcacgccaagggaatcaaggactcaggcacacaagaagtgagtttaagagcagaggtttaataggca aaagaaagagaaaaaagaatagctctcttgcctgcacagagagaggggcacctgagtggatcttcctgttttgtggtgaa atgcaaggcattttatagacgagcttgaggaagtggtgtctgatttacttaggacccgagagattggtcagaccaggtgt gatgtttacatagcatacaaagaagctggccatcccatcctaatcttttattacgcagacggggtctatacctggctggt gccatgttgtctgttccttactgtacacgtggttgacaaagaaaagggaagatgaagaatccatgttgaacatgcctggc ccccagatagtcttttcctattggcacagctgccggcattcactcttgcaagcttccagattgcttatctatgtctgcag cccaattttacaggttgctctttgctagaaaagaaatgatttgggggctgcttttcattaaaaggaaaaccttaccaagg ttaaaaagaaaaaaatttctttttaatgcctatgttactgtgaacagtgtcgggataaggctctgagagccagatgagga tgagttatccaatccaaggatgggggtctggaggaaaaaatcctagagagcattgctgcagttgaataaggattagttag aagctactgagtggagcataggagtaggaactcttatgcaaatgtgcagaggtgaaataaagcaaggtatagtccaggtg cctaaagtagcacagctgacttgagatagatgatagataggtagatagatggatagggtacatagatgatagatagatag atagatagatagatagatagatagatagatagacagacagacagacactggtgtgagtgtgggtgtgtgtgtctggctgc gtgcatgcattcctcctgcaggagatcaggagcagtgggcagtatggagtgacaagaagattgggaggtactccttctag ccctcccctctgctctgccctccactggagcagaagcaaagcatatggtgaaggggaacaaggagtctccccagcacagt acccgagtgcattagctatttatcactccacagtccccattcacgtgttaattcagcatttattgaatgcttactgtttg caatgtctatgtcaagctgtcaagtgtagtttttattctacaggccacaggcaccccctaactgtgttaaacaagatggt agtattgagacaggaataataagggtggtcacaggagaatggaagattccaggcagcagtttgactagtaaaaaaggaaa ctgttgaaatagctgcataatccaggggtcaataagaacctgagaaccagggtgtgagccaaggctggttaaaagcaact ggatccaatatggtgctgagtttctcctaggttttgcctggaacctcattatatgctcaataacataccaaatcacacac ccaccagggccattccatttcctggaacactcatgtttggtgtaaaaatgggtggcaccacagctctgagaaatctttac ctttttcaggaaacttcatgaatattccatcctttggttaaagaaacccataatgtagaagccccaaaccctactgggcg caactctctctctcttgagtatgcctgcacttccctttattatttatttatttatttattatttatttatttatttttta gatggagtctggctctgtcacccaggctggagtgcagtggcgcagtctcagctcactgcaagctctgcctccagggttca ggccattctcctgcctcagcctcctgagcagcagggactacaggcgcccaccacaacgcctagctaattttttgtatttt cagtagagatggggtttcaccatattttattttatttttgagacagggtctcactttgttggctcgctgcaacctctgcc tcccaggctcaagcaatcctccaacctcagccccccaagtagctgggaggacagacgtgcaccaccacacctggctaata ttttgtatttttttttgtagagacagggtcttgccatgttccccaggctggtcttgaactcctggactcaggtgatcagc ctgcctccaccttccaaagtgctaggattacaggaatgagccaccccacccgaccacactcccatttcttgagtgtgtgc attttgctctgcaataaatctctctactttcacttttctctgactcgtccttgaattccttcttgtgacagcgtcaacag cctggacaccaggtgcagtcaacgtctcaccagtgtttagggacctcccctaatccactggtatcagcatgatcagactt gctttttcagaaaaagccttctgtccatagaccaaagggaagtgactcagagaaggggcaggaggaatcacaagctccct gcctgaccaggcctggactatggcagagacagtgagatggtgagaaagcaagggtagacagccagccaaatccagaatat agaaagttctacaggaaaaggtggggccaaggtgggacagggggaaaggaattgttgcacattaacagtgcaatgcagag cactggtcttgtttatgtccaggttagaacaaaccaatgagaaagcacatctttgagacaactggagaaatttgaacact gactagatataatattatgttaattatgctttaatttggggtacaataatgcttttgtagctatttctaaagagtcctta tctcttaaggatacactctaaaatactagtggattaagttatatgatgtttagactctttttaaaataatccagtggggt gagaggcagagggaagggagaggagcatagaggaaacagtgttggccatatgtttgtaattgttaaaactgagtgatggg aatatggagatttaacatattaatactattttctgcccatgtaatatttgaatattttcataataaaattgagagagaga taaagaaagaaaagagaaaagaagagaagagagaagagataagggaagtggaggaaaaagagctttcttcaaggaccatt gtggtggacacaaatgaaagatacccccttcctactatgaattctaggtgtgtactacccaagatgagtcaatcggatcc tagcttccagaaatcgtgagcatgatgcagccctacagacgcagtgccctggaaaggagacccatgaccatccaaggaag atgtcccatcacagaactgccctgggtcatgtgttttccaagtccacatgtccggtagttccttctttcctatgaccaat gccaccagtcttccagcactgtcctttattgctaggcaaacctgagccatcctcttcttcttgcaacttgtgcctgaagt aacatggacacaaagtccccacttttcccacattctcagaatgaagtagttctccctccacactttaggtgctagaggca agtggattgcttgagctcaagagttcaagaccagcctgagcaacatggcaaaaccccgtctctacaaaaaatacaaaaat taactgggggtggtggtgtgcacctgcagtcccagctactcaggaggcagagaaggaggatttcttgagccctgaaggtg gttgtgttacgtgcattcatgttaagagaccaccaaacaggctttgtgtgagcaattaagctttttaatcatgtgggtgc aggcagactgagtctgaaaaaagagtcagcaaagggagatagggatggggcggttttataggatttgtgtaggtagtgga aaattacagttaaagggggttgtcctcttgcgggtacaggcgggggtcacaaggtgctcagtggggagctcctgagattt attgtccaggagaaggaatgtcacaaggtcaactgatcagttagggtggggcaggaacaaattacaatggtggaatgtca tcagttaaggcaggaactgggtattttcacttctttgtggttcttcagttgcttcaggccatctggatgtataagcgcag gtcacaggggatatgatggcttagctcgggctcagaggcctgacattcctgtcttcttatattaataagaaaaacaaaac aaaatagtgatgaaatgttggggcagcgaaaatttttgggggtggtatggagagataatgggtgatgtttctcagggctg cttcaagcaggattaggggtgacacaggaacctagagagtgagagagattaaactgaagaaagattttgtggtaaggggt gatattgtggggttgttagaaagagcaattctcatatagaatgattggtaatggcctggatgcagttttgtatgaattga gaaactaaacggaagacacaaggtctgaataagagaaggagaaaaacaggcattaaaggactaagaactgggaggaccca ggacatccaattagagagtgcccaagggggttcagcataattatttgcttggttggtgagtttttggtctccatccttga gttttttttatgttgtcatatgccaggccagattgatttaggtaaaaacaacactcttcatttaaaaatatacagagttc tcctttctcagcagtgagtaagtcaaggcctcagcagttttggaggaaagagaaatgcaaaggaagcaattgtttgttaa gaaggattagaaatggctaggagagagtgagtgagattgatagtgtggtggagatagctgaggagaggtagagggtggca taagaatgggaacgagaataagagtgagtataaaagtaaagaatagaacttcatcagggtgaaagtattggagggtgccc tgtcagcaaagatcatctgtccactccaagagggagtcaagagtggcggattggggatagtaccaggagatatccactat gatggtttggaggaaaagtgtaaactggcagtgtaaacaggggcagggcatttatgagtcattgagaatggtgaatagga gtatgactagacagaagatagtggagatgacaaattttgggggcacagtccaaatagtgggggtgactgcgtagagctct gttgcaaaaagtagggtaaggataaatagacttaatagaatgaagagatgtattaggctcataagggttattattgttct tcagaaatgcgagtgagtttaagggaagtaggggtgagtacttgcgacttccagaaggaagaggagagatcaggctggct gtctgatgggcacagctttattctggaacagtgaatccaatggggagggtcgtgcagacggatggcagttggggtgct t aaatgaccaggtagggtccagtccatcaaagctgtagagtgtgaggggtcagacttgacaaggactgattgcccagctaa ggtatcttcacatggctgggagtttggaggaggcaagagaagattagcagcctggcgaatttcctgtctagcctgctgga ggactggaagataaaggcaacaggtcgtgggcctggatcctgtgtgaggactctagcagcacagccttgtatttcagctg tgtgtaaggaaaaaggatgggacgagtcggggagtgctagtgtgggagctgtctccaggtcctttttgagagagtgaaag gaagaatggggaaaagacttatggtctatgggattagttaaattaccctttgtgagctagtaaagtggtttgattaggat agcaaagcccggtatccaaagttggaaatatccaacaatgcctaagaaggaagggagttgttgtttggtggtgggggttg gggtctgggagattaactgaacagagtctgcaggaagggtatgtgtatgttgatggagcattataccaagataggtaatg ctaggggaagaaatttgtgcctcagagggcaatactttgtacccctttgagtaaagatgttgaagaagcaggctagtgtc ctgctgggaagattggtaagaggggctgcaaagaagaagatcatcaacatattgaataaggtgggaggtagatgggtgaa aagaaagcagatcatgagaaagggcctggccaaagtaatgtgggctgtccctgaagccttggggtagaaaaatccaggtg agttgttgggactggtgggtgtcagagtcagtccaagtaaggcaaaaagaggctgggaggagggatgcaaggggatagta aagaaggcatctttgaggtcgataacagaatagagttgtggaagggtgtattgaagataggagggtgtacgggtttggca ctataggatggatgggaaggacgatttgatcaacaagacgaagatcctgaacaaacctgtaagacttgtccggtttctgg acgggtaggataggggagttgtaaggagaatttgtaggctttaagaggccatgttgaaacaggcaggtgataacaggctt taacccttttaaagcctgctgtgggatgggatattggcattgagcggggtaagggtgattacattttaatgggatgataa ggggtgcatgatcggttgccaaggtaggagtagaggtttcttatacttgtggattaaggtggggagatacaaggggagga tgtgaaacaggtcttgagttgggtaaaagtgcagcaaagagatgtggctgcagcccaggaatactcagggaagcagataa tttggttaaaatgtctcagcctattaaggaagctggacaggtggggataactaaaaaagtgcataaaagaatgttgtcca agttggcaccagagtgggggagttttaagcggtttagaagcctcgccgacaatacccacaacagttatggaggcaaggga aacaggcccttgaaaagaaagtaatgtggagtgggtagcctccgtattgattaagaaggggacagacttaccctccactg taagagttacccaaagcatctgtgatggtccaggaggcttctgaggtgatcaggcagtgtcagtcttcagctgctaagct gagaagatctgggaaggagtcagtcagagagccttgggccagagttccaggggctctgggagtggttgccaggcaagttg aacagtctgatttccagtggggtctcgcacagatgggacattccttggcccagtggccagatttccggcacttgaaggaa gatcctgggggaggaggtcctggagaaatgcctggcccctgcagtttaggtgttttgaagttcttgtgtgctggagatgt ggctggggtttctcttacagcggaggcaagtaattgcaactcagaaatatgttgtcacttggctgcctcttttctattat tgtacaccttaaggcgagggtaattaaatcctgttgtggggtttgagggctggaatctaatttttggagctttttctaat gtcaggagcagattgggtaataaaatgcatattgagaataagacggccttctggcacctctgggtctagagaggtaaagt gtctaagggttgttgccaaacaggccatggactcagctgggttttcatatttgatgaaaaagagcctaaacgctaactga tttgggagaggtcagctaaagaaaaaggagcattaaccttgactatgcctttagctctagccacctctctaagaggaaat tgttgggccggtgggggagggctagttgtggaacgaaactgtaagccagaccaggtgtgaggagagaaggtgaccaaagg tttatagggtaggggagcagaggctggggaagaattgggacctggctaggcctagcgaggaacagcctggggaggagggg agaaatcagatgggtccgtagaaaaggaggattcaaaggactcagagcttggggtggagactgaaggaacagacaggaga gaaagaggaaagatttgggatgagtcacattgggagcagagactagagagggactgatgtgtaaagaatgcctggacgtc aggcacctcagaccatttgcccattttacgacaaaaattatctagatcttgtaggatggataaatcgaaagtgtcattct ctggccacttggaactattgtcaagtttgtattggggccaagcagtattacagaagaaaataagatgtttaggtttttaa aagagtgcataaaagaatgttgtccaagtccatgcccttcttaatcaatatgggagctacccactccacattaccttctt ttcaagggcctgtttcccttgcctccataactgttgtgggtattgatggccaggcttataagccccttaaaattacccca ctctggtgccaacttggagaggtcaggtgttagtcaaaggtgttttaagttttaagaacacaggctaagggagaagaagg gggaatgaagcgtggaaggttgcccatagtgaaagaggtaagtttaaagagaaaggtagagacatggagaaggggggagg tgagcagccctgggctgtcatgtgggttagcagccaaagctggtgtcccagcaattgacttaccaccaagggaatgtggg tgaatgaccaaggcaggcatccccccggtgatcagacaccaaatggaatgtgggtgaaagatcaaggtaggtgtccccat gatgatcagacaccaaaggaaggctgtcttcccaaatccatgatccatgttggagtttttgagttcatggataaaatgtg tctcctttgtctctactagagaggaaaaagaactggaatttgaaggacagggagattgaagggtagggagagaggctgaa gaagagagtgaggagaccgcttacccggtttgaaattggtgagatgttccttgggctggtctgaggacctgaggtcgtag gtggatcttctcatggagtgagggtgaggagaggggaccaatctcccgaaggagtcaccctgtccggggtcttcggcacc aaatgttatgcgcatccatatgaagagaccaccaaacaggctttgtgtgagcaataaagctttttaatcatgtgggtgca ggcagactgagtctgaaaaaggagtcagcaatgggagttagggttggggtggttctataggatttgggtaggtaatggaa aattacagttaaagggggttgtcctcttgcaggcaagggcaggggtcacaaggtgctcggtggggagttcctgagactca ctgtccagaaggaatgtcacaaggtcaattgatcagttggggtggggcaggaacaaattacaatggtggaatgtcatcag ttaaggcaggagcggcctattttcacttcttttgtggttcttcagttgcttcaggcaatctggatgtatatgtgcaggtc acagaggatatgatggcttagcttggactcagaggcctgacaggttgctgcagtgagccaagatcacactactgcactcc tgcctgggcaacagagccacaaaaaaaaaaaaaaagaaaagaaaagaaaaaaaaagaagaagaaaaaaaaattttttttc caccaagaatttagtaaaaaattatagggaaaagtgtcactaattcaagggaattgcactgaaaattattcattcattca acagatatttattgagaagcaagtatgctggtgctagggttacaacagcgcacaaattcttgtattcaaggaatgaggta agagtatgcagataggagccagagaggtcaagaggcaattgcaacatagagtgacacgtgctccagaacacataggaggg cttccaggccccatgctgggctatcagagctggcttcctgcaggtggtgtggctcagctaaaacctgagaaccaagaatg agccttctgatatctcagggttaaatcggcacaaatgaaaccattttataaccaaacaacattttccctcctgaactgca ctttttctagaacccatttaatccttcctaacatgttcaatccagccccgtgatttttcagtcaaatgcaagatgcgtag gattccttttctgttcagtgctccccagccaatctttttcccttctcccaccccacagttactaattccagcgtttcagt tctcagcagaggatgacagttccaccaggagacatcagtgttatctggagacattttagttgtcccagctgagggcacag tgctgctggcatctagtgggtgaaggtcaggaatgcacctcaacatcctggaacactcaggacaatccccagcaacaaaa acctacccatccagaacatcaacagggctgtggctgaggagccctgctctagtgcttcctccttactgtatcctcatcaa ggagggctctggggcatgtcaggggctgctacaggctcctggcagatttcggcgacttactccagacttgtggaacattc aggattcttagcatggccacaggagagtcaggctgtccacaagcactctctctttcttcacccactcattcctgtcactc taccatttccactgccttcccaaatgcccatcgtgagtcccaccaggggccagaacaccactctctcaagcctccccagt ggcgcgtgcacacctggagaacatgtctcacatcccccagccagcgagacgtcctgagattccagcacttctcagtgtct ttcccagcttgtttgtatctggaatggggtggggtctctcacacaggagaaattacaaggaaaagtgtacgtgacaggaa tggaggaatttctgtggaaacggtgtgtgagaaaatgtaggaagaaagaaacttcaggaaatggtaagtggcatcttgag agcagaaagtgagaagggagcagaaagaaatggggctggaacctgggaaggagaggacaggtggggatggccttgcacac cgtgggcactgaggagtgtgggcccatggcatgggtggagaggagtttcaagatagggagtagattcctattttgaactt cggattgcccctggcgatgtggagactgtattggaagaaggcaagaatggaggagagcccctaggtggaggtttggcaat gctctctccagaatatagcagaggcctcttccaaggtaggaaagccctgactggagagaagttaatggctctgagggctc aagggaggacttggattatcaggacttttagggaggcatatgatcaaggcttgggtcttggcccattgaaatggggagca ctggttttaggatgtgggtcaattagtttggttttcaggacaggctgagttggatatcctgggggacctccaggtggcag tgtcaggggaagctggatgtgctgacactgaactcagcagagtgactgagtagagatcgacatctggggtcacaggcagt ggatgccgtaggggtggactcaatagctcaagcagaacccggaggaatgcaggcagcaaagggagccctaaagaacagtg aggagatgtgccaagaaagagccaaatccgggggattggctgtgggagagagggctgtgggagtaagaggaagtgtcagc aacgtcaaatgttgcagagacatagagtaaggtaagagtggaaaaaacatccatggaaccctgtgatgcaatcggaatgc agaaagactttgtaactcctgcctggtctcctcctctgcccactcatggcaaaggaatacaaagtaatgttccctccttc cgcctagaaaagcacaacttctgcccccaagccctgggctctcctgagaggacaggaccagcctctgaagttgaaggtcc tggttctgcccccaagccctgggctctcctgagaggacaggaccagcctctgaagttgaaggtcctggtttaccagatag ggaaggggccctttccaagaccctttccagaaggtgtggctgagatgggaaccgtggactctgtgcagatgtaggagctg gctccagtcaagtgctaggaggttgtgggtcctgggaaggaagaggctctggagcctctgtggagactctgggactgtcc ttgggggagacgtgagcaggaagaagcagggccttcacagtccccagcttaggggcctcaccacccagactgaagaccag gaccaaaccctttcctgcacagttacaatgtgtcatttaattttactaaagggaatattttttaaatgaggatgctactt tgtgtattaatttttacctctattcataaaagaaacgtttcttatctatttaagatgattcatatcagaccagtgtctgc ccaactcgactgaccctgtgaaaactgggcacttcacactccaatgatgatggatgagtccccagcagcatagtttaagg gagtgagtgggcagtgtggcctcctgtgcacgtgacttcctccttcagtgtgcccacatgtgggttccacggtcttgtga cattgtggctttagaaatttctgtttccattttctatcattcagagtaaatgaaatttgcaggaaattcagaaccttcca cctgtacagtggatactgtgagactctgcccagatgccctcttcaagccaatgcatctctccatgctcccactcccatag atgggaacagaggtgctggaactcagatctactcccctttctgggaactggagctgcctgcccaggcaatgcccccttcc cagggatggctgagccaatgactggctaatgttggattgcagaggcctagcgccctcccctcaattcctaattccttgta ggaataactgaggcctcctctgtgaccacgtgggcagcttctccctctgcctggtcctgtcttgttctctcctttccaat tgtgtctcctggaagccctccccacaagtctgctgcatacaactctccttctcagagagcctgagccctggattcccagg aatccagcctaaaatagtctggcatttggtttcaattttctctttcactaagactcagtcacaggtgctaataaataata aaatgtcaccaccttgaattctatcactctctcttttcttgccccatctctgacaagtaggtggtccctcaagaacctga aaagcagacattaggaggaaaggaggagtgggggcaagaggcccacacctcacctggccggctcccatccatgcgccctt gactgaggtaacacctaccctgggaatccttcccctgcctctcgtgagccaggccgggtgctcttgggacagctcccact gctcctgtgtgctcccccagcttggcacatgactccctgaattatagtcagttccgtacctgaatctccctctagaatgc cagtgccacgaggacagaggacggttccactttgttcactattttctccccagggtctggcaaagttcctgggacttggg agaggtgtccttcaggagcttggcagaagccaaacggcacacttaagtagggcaactgaggtgagtttaatgaaggattc tatacaaaaatttggacaaggtatagggaggccacaatacacagtgcagtgcctggtgccagtgagagcagggcactatt cccactgcaaggccagacagggcaaggggagggagctgcctgacaagagctgcccttacgtcaagggacacatcagccca ctagaccccatcaggagggagccagggcctgactcccctgaccttgctctccaatcttctgcctaaaattccccatcagc caaacacaactgaaaactgaaagacaggggagcctgctgttaataaggtgagcttcccccagaataaagctgggtagaga gtggagaatggatatggaagggcaaaaggaagatttataagacagtgggcactaaatatctatgagatgaataaaggaac cacattttacaacaaacggtcattgaaacgctactcaatggaaagagatcatttcggtcactgtctggtgcagacaaatc aaagcccacatgcatcaaaaaggccatgtccgtgtaactccgacacggggcagacagcaaggctgaagcctatggggtat gtggagccggaactgagagatcctgatgtaaatctagcacttgggaaaagggggactagaagaaattcacccacaggcag aggaaaacacaaacacttatctatttttgcctaggctttaagtggtatgggaaaaatctctgagactacaaatcctgtgc ttcatgcacaggtttataataccctcaaaatggaagaccccaaaaccaggcgcggaaaattcatatcaggccattgatgc cctcaatgttcccggctgaaacaaactcaaaactcctctggaaaggagtgctcccacttcaagccatgaaaagctactgc agagaaaataatccccagtcaagacacactcacattgaaactgcaaggcacacaaggaaatggatcaccttgagtgatag ctggcagagctaataaacctctgtatacctctaagaagctccacgcactagtataacccttaaagatttgatgaaatcat tactttattaaaattgtttttataaaaaatcaaaatccaaaaaaagcaacaaattttataccagagccaattcggtatat acaagggtgtcttactcttttggaatttgtcttattgtcctaactcagcacattgtcctggtctatgaaaagtcctagaa acccttctaccctctgtaatgtaggagctttaactcaatagggttttttaaattcttttttcttgtctttttttcttttt taattttttccattttttcaagtcaaactgaagaaatatttttcttttctttctaggaatgcatattcaccccccaaggc cacttgtctcctgattggagagtattagacaattctcaggatttctttattttccttctttattccataggattgggaaa cccagtaggattgggtttaggcatatctctaaagcaccatgtttcaacgttttgatgtaagattgtgccctatttct gt tcagttgctgccagcagatgttatagttttaaaactagtttttggtcattgagatattagaggagggaagagtctgctat cctgctttactcatcttcatctacactacactgtcatcttcactgcaaagtcctgtattaatgtttttagattctataac attttaacaggtgtcaaaaaatcttaagcaccacttcagcttgggaatctctaaatgtaatggtgtttgtgggctggact gatgtctgcgtcttgttgttgttattgtctgtagtaatggagagccgggagatcctggacacttcctgttcatgggcact tgatgcattagctgccccagcagctgattacatttaaacaaggatgtgtgggtgaacccagggagaccaatctcagtgga atggtgggggcagaagccaggctgcagggtgtagagtagggaatgagcagtgatgaagtagaaacagagtttggacaact agtgaaactgcctggaagagggggagaagagacagtaaatggtctgaccaatgtttgaggtcaaagtgggtttgtaatct ttatttaagggacagatctgagcatttaaaaattctgaataatctaatagagaggaaaaagttgggactcaaagaaaatg tgggaaaaaatgatgaaggttaaacggaatgagatccagagtgcagggggagagattagcctttggtgttagaggagcaa ctctgtccatggagagaggaaaaatgtagacataccacagttgcatttgaagttggggcctgaggagttgaggagttctg agaaaagcagaagatgagatcatttcctgagagtaaatgggagtcattagaacgggggtgaagagactggaagctttagg tagcttgaaatagttgatggaaaaattggataaagtgacaatttgtcacactcagaacagctatcagggaatctagaaga atctctggaagctagttgaagatcttaaattaccaatgtatcttgtccacatagctaagcggttttacttatttttattt ttttgaaacagggtctcactctgtcacacaggctggagtgtagtagtagtagcacaatcacagctcaatgcaatctctgc ctcccgggctcaagcaatcctcccaccccagcctcccgggcctgggactacagacacacaccaccactcccagctatatt ttgtacatttgtagagacagggtctcgccatgttgcccaagctggtcttgaactcctgggctcaagtaatctgcccacct cggcctcccaaagtgctgggattacaagcttgagcccggctgctaagtggttttaaacagctgttctcggaaacacacac tcaaagaaaaaatgtagaggataatttatctaaggctggggcttcaagagaggtcagggtgttgacaagagaatgactaa gtggcagactactggatctcagctagataaagagggatgtgatcgtgggaggggctgatagtcagaggctggaaggcttg atgaacaacacatattacacaaagaataaatggagtgagagaaaccaaaggagtaaaagttgtcatcagaaaagtgagaa attttattgtgagaattcagtggtaaatcaatgttaacaaacctcagctgggcactagtggagtgaaaccgaaggccagg gagttgagttaatgagctgagacttgggcaccagatgggggtccacatggacaactaagccaccaggatgatgtgggaaa ctggggtgaatagaagccccttatccatgtgcacaagtcttgaataaaataggggcaaccaggcagtcagtggatgatag cagtgaggtggagcagagagcaatgtagttggagaagtggagcccacagcagtctcctttatatctagaagggaattaat agccaaaaaatggcaccgaggccaaggatgtcaccttctgactcccaaatctgagacagatgtgagagggaaggagtatc ctcaagggacaggagatggtgcgaatgtttttggcataaatcaaagatgtcagggaaattgtcagaattcaggttccaga gacacagaggaaaagcgtgggagaaagtggaatattgggaggtgagattagggcagaggaagcacaaatcaaagaacgag gaatagaaaaagtcatatgagctgaggagttggccaaacatgacagaatgggaatatgatggaattaagtggctttatgt gttccaaaaggattggtccacgcaggccacaggaaaatgggaggtaagaagaaagggatcgaaatgctgcaaagtgtatt acttcatggtaagcaaaggactcaagactctagaaaatgatgcccttccttccaagactatgttagtccaaatctttcaa gatacagaacccaaggtggggtctggcatacaagaagtataatagaggaaatgtctgtgacatttgcaggactgcaaagg gagccaggagaagctgggaaagccatgagatcacaagcaggtctgactccaagtgaaggagatggggaatgacgcaaggt ttggctgaagcatgtgccaaaggcacccatcagaggagtccctctccaagggatgggcctatcatagtgtccctaatagt gtcatggagtgggagcagcccacggagggcacagccttggcatgaacgcagacatgggtctcagagtgcagcagctgggc ccctcagtcaattaggctccctcagagctggggcaggaggtgcactagaccacacagtaatatttatttattattaattt aattaataatattaattta aatttaattaataatatatttatttatttattattactagaccacacagtagtatttgt atgtctaaggaagcatttctcagaatatactcactgaacttttagcctataagtacctgtatgaaaattttaaaaggggt ttcatgatcaaaacattttgggaaacactccataccctttcttcctcatgaaggatcataatgcctattagtatatgaag ggctctgagaagtcctgtagtaaagaaacttgctttagttttttagtccagcaatttttcaaacttaaatgagcaatagc ctcccatccttttttttacactttttagcatactgcggaataaactcaacatgcattgagaaagactgctttagggaata gtcaacactatttcactcccagtaagtacatataaaatctgtatttccagggtggattatcaacacagctgtattttaga aatattatctgccctcccaggtatcacagctactaattattgggtactgaggtggaattttagggatcagccaattatgg gaaagaaaatctgggggcaggataagatggtctccgaagccttaaaattatatgccattatttacctctttgatctacta ctcaatatcaaacaactaattcagaagaaaattgattgttttctaaaagtagtttttctacatttcccattaagaagcag tggtatttaaaacttataatggctattatgtgagat a cactatcatagtttttctctatacaaattttctgtaacatt ttatttgctaataaaaattagatagatggattgactaattgataatctaagaaagattatatttgaagaagccatagtaa gggacagattaaattatcatcagtctaaacattctaatacctatttctctttttttgaaattttccaaatttgttattat gcatttaaacaataattttttgaacttttattttaggttctggggtacatgtgaaagcttgttacataggtaaccttttg tcatgagggtttgttgtacaaattatttcatcactcagctatcaagcccagtactcaataggtatcttttctgctcctct ccctcctcccaccctccagtctcaagtagacctcggtgtctgttgttcccttctttgagttcatgtgttctcatcattta gctcccacttataagtgagaatacaaggtatttggttttctgttcctgtgttagtttgctaagggtaatagcctccagct ccattcgtgtttccacaaaaaaacatgatctcgttcttttcatggctgcatagtattccatggtgtatatgtaccacact ttctttatctaatctgtca tgatgggcatttaggt attccatgtctttgctactgtgaatagtgctgcaatgaacat tcacatgcgtgtgtcttcatggtagaatgatttatattcctctgggtgtatacccagtaatgggatttctgtttttagct ctttgatctaatacctatttctcaagatcaagttagatctctaaaaaaggcatcatcctagcatttccccatcccttccc tgaactaaatttaatgttgtgtgtatcaatcagcatacagtcaagacagaaaccacacatgaacattaaatataatgagt tattaacttataaaagggtatgaactactaaagggggtaaggagaatgctgaagaatgcaggaatggcagatgtagagag cagccataacctctaagctaaggcacagcagccaaggaaggggcgaactcaaaaaatgccctccctccccagctgatcca cccttgttggagggggtgtggctgcaacccaatggatgcccaagaagtttgcagagttgtggcaggttggggctgctgag caggaaactgcccgaaggggtaccagtgagattcccaagaatgtgggcatgcctctggcgaggaagacgctcttggagtg ccagcaaaatttactaggaagctacccagtagggtgccagcaaaagtcagcaggaagccactgtcgtggtgtcggcaaaa ttcactgaggagtgggcactgcagggtctccacccagcactggcaaatcagccaaaagaacaaaaacaaaataaaaacaa atcccagaaccagaaagaaaaaactctgcctcttactgcgaccctcttatgccttctacagcaactggcaaaggagaaat gtttatggggtccagctctagactcacaaagcagaacacagaagagtgaatgaagagctgaaaggcgataaatcagtaac tggagcctcacatcctttgccttttttattgagggtcaatatattaagaagaatatgtctgcgtcttcggtaaaattatt gctaaggttatcacccagtgtgtgttttcaacctccctgatataagaacttagtgacaagaaagaatgagacaatgatca tgaactattggacccaaccatttgtggctttagtgcccatcttctcagcaaggctttctctctctctctctctctctctc tctctctctcttttttttttttttttttttttttaagatggagtctcactctgtcacccaggccggagtgcagtggcaca atcttggctcacggcaacctccacctcctgggttcgagtgattctcctgcttcagcctcccgagtagctgggattacggg cacccatcgccacccctcctggctaatttttgtatttttagtagagatgaagttttgccatgtcggccaggctgttctca aactcctgacctcaagtgatccacccacctcagcctcccaaagtgctgggattacaggcatgagccaccacagccagctc tcagcaaggctttttctgactacactatttaaaatgtgatccctgagccaccttggcctctcttgctgtccttccctgct tcgccttctccatagcacttctctcctactaatctacaatttacttgagctctgtgaaggtcaggatttttgcctatttt gtccattggtgcatccccagcacctggaacagagctaggcacaggctaggcactctagaaatacttgctgaataattgaa ttaagtaaatgagtgatctacacgtagtggggaatgagagtatacagtgatagttccttcgactaaaactggggtcaaat tatagtgataaagaggaactcagaccttcagaggtaagctttgtggaccacttgccaaggctgcagaatgtgatgtcgtt tcacaaacaaggaggccctattatggcttcagatatgagaataataaagagaactttcctttcgcctcaactgcagcctt ctaaactcttccttccttcctatgtagaagtttcaaggacctcatggcctgagtgtggataggcagaatgctgggaatca ggcaaaaataaaataatactgaaagtgaaggtcatgctaatattagtaagccagggtgatcctgaatttacaaaacattt ttctttgggaaatttcacacctcacatgattctgtgtttttacttgggaaatttcacatctcacatgactctgtgacatg cggtacatgaggtgcctgactgctgtttttgtcctctactaatgaggaagagtgtgcgtactcccagcgttttgcaagtt tcaaagtctgacttgactttccttccttttcctggaactgatccatgagtatcgagagtaaagctgcccgcacctactca ttcaagatcctgagtgtcctgcccagctgcaggaggtggagagacccaggaggaggggccactgctgatcccaggctgta gggggtgggaagagtgtcccagggcaccatgacccccactcactcactcacaggagacccacacaagagaggagagggca cttacagcttaggttcccaccagcaccaactcctctgccatcaaacatcattgtgtttctctttctgccttgtctgtcgg cacacgtggagttaaatttaatgctcaatcacatatttgtctgggctctttctgtgtttatttttctcttaatagttctc tctcctcccttcctctccccgcccctcctcctccttcttcttttttttttccagagacagtgtctcgctctgccacccag gccagagtgcagagtggcatgatcatggctcaccgcagcctccaactcctgggctcacgtgaacatcccaccttggcctc tggaatgtctgggattacaggcacttgccactgcatctggctaatttttatattgtttatagatccgggatctcactatg ttgcccaggctggcctcaaactcctgggctcaagcgaccctcccacctcatacttctgagtagctggggctgtaggaatg cgcctcagtgccaggctagtttcttaattttctatttctattttgacaggtacaaattttgtattcaatcctacctcaga cacatctttggtgggaaaaggatgtcatttaatcaatatataaattctaagcaaataggtctgatccccaaattaggtta gtcacagctgctgagtcgttgacccaagagaagctcatctagattttttcattattttcaagttcctcttctcggttcgt ccttcttccagaccatgccctccccgtcccactctcttcccacagcctcccctccccacagcctcctcccaccattccaa atctgggctgttctctcaatttccttctctctggactcaaacctaccctagcccccagcctcagtttggggttaaacttg tcctcctcacattctctcccacccaacttgatgtcgcctctgtgtcatcaccacgggattttcctcctctgggttctcct tttccgagtggggtcagctcccccatgagtcacagcaccaatcacttctggctgcttgcaaacccctttgctttcctcag tgttgacacccagggcagccctatgctcactgccgctgagaccccacctctgcccctggccttttcccagctgacatcac cctgtggcttccattttcctaaaattctcttttgaggcctcagtcttaaccaaagcacacagtgcccctcaaaaatgaca ataaaaacccaaacacaccgtgactgtcatggcaggttcctggtccccgtattgaatcagcgggtgggtttctgcgaaca ctggtgagaggccgcattagagggtcaggaccctcaggtctggactcgtggtcaccacataccttcctccctgctgacag tagctggtacctgttacctactcagagtgtcacatgccacaagccagagcgtcttggcagttctcagcaccttgacatca cttccttgctaccactcagagcggcagtgacacagttcccttatctcagaaggccagaagacggctgtcaaaggtcacag ggaaatcaaaggcggggtacagggccagagggaggaggaaacaacttcccggttgctttcagacgcttcagagatcctct ggaggcctgggggagcttttgagtactttatttcagttggtccctgagctcggtgagtggggcgggtagagccaccaggg gaatcaacagtggtttctcgtgcccctcagggtcaggagcagtctgatcaaaaggagggcatccactgtccggggccatt cccacagctcccggatgctgggtctggaggctgcgcccttcccctgcaggagctcagcccagtggtaagtcatctgtgtg tcatctatgtatttaaccccttatggccatgttgatgctgagcatggtttcacttttgcaaacatttatttatacccttc gagagaaaaacgtctcagctgtcacaggaagctgcttcggggggtgagcaaactttttaaaatgcagaaattatgatcta cacccgtttcttaaaagtaagccatcgtacttggttctctttaattatatattttcttacatattgtgttcatgtaggca agtcctgtttctgctaaaagaaggtaagttctaccaaggcggtgtcatgccagctttatttcccgtggcacctggcacac tgctaagcacttacatgcttaacaactagattgggaatggtgctgctctggggaagtgggcacacgttaaagaaatgttt atttcagtcttctgaaatagggaattactctggctaaaatgtagctccagaaagggaaagtggggctgtatgaatccagg tccagtttgttgtttcctccaggataaggcagctgtcggaggggaaaatcatctcccatttctccacagggcagtctgaa gatggccaattacacgctggcaccagaggatgaatatgatgtcctcatagaaggtgaactggagagcgatgaggcagagc aatgtgacaagtatgacgcccaggcactctcagcccagctggtgccatcactctgctctgctgtgtttgtgatcggtgtc ctggacaatctcctggttgtgcttatcctggtaaaatataaaggactcaaacgcgtggaaaatatctatcttctaaactt ggcagtttctaacttgtgtttcttgcttaccctgcccttctgggctcatgctgggggcgatcccatgtgtaaaattctca ttggactgtacttcgtgggcctgtacagtgagacatttttcaattgccttctgactgtgcaaaggtacctagtgtttttg cacaagggcaactttttctcagccaggaggagggtgccctgtggcatcattacaagtgtcctggcatgggtaacagccat tctggccactttgcctgaatacgtggtttataaacctcagatggaagaccagaaatacaagtgtgcatttagcagaactc ccttcctgccagctgatgagacattctggaagcattttctgactttaaaaatgaacatttcggttcttgtcctcccccta tttatttttacatttctctatgtgcaaatgagaaaaacactaaggttcagggagcagaggtatagccttttcaagcttgt ttttgccataatggtagtcttccttctgatgtgggcgccctacaatattgcatttttcctgtccactttcaaagaacact tctccctgagtgactgcaagagcagctacaatctggacaaaagtgttcacatcactaaactcatcgccaccacccactgc tgcatcaaccctctcctgtatgcgtttcttgatgggacatttagcaaatacctctgccgctgtttccatctgcgtagtaa caccccacttcaacccagggggcagtctgcacaaggcacatcgagggaagaacctgaccattccaccgaagtgtaaacta gcatccaccaaatgcaagaagaataaacatggattttcatctttctgcattatttcatgtaaattttctacacatttgta tacaaaatcggatacaggaagaaaagggagaggtgagctaacatttgctaagcactgaatttgtctcaggcaccgtgcaa ggctctttacaaacgtgagctccttcgcctcctaccacttgtccatagtgtggataggactagtctcatttctctgagaa gaaaactaaggcgcggaaatttgtctaagatcacataactaggaagtggcagaactgattctccagccctggtagcattt gctcagagcctacgcttggtccagaacatcaaactccaaaccctggggacaaacgacatgaaataaatgtattttaaaac atctatttaatgtattttaaaataatttgtaagttgattttaaaaccaatttaactacattccaaattatagacagccca tttatatgggagtaacttttcaggctcattgcctcgccggtgatgagaagaactagctagctggaagctgtgggaaaaag aggtaaggtaacttgttctgtcgaagttctctaaattctcttgcttacttgccacacccctaggcccccagcttccccta acccaaggtttctggtattttctcgtactttatcaagactatggaatcttaggagacttaacaaaagcaaatgagaaatt atgtttagaaatgtctaacaaaatgaattctttgtccttttaagtataacacatacctcaggcctcaccagcacataact acaaaaggttgtcccacttcctttctgtggctgagttagtagaacacaggctcccacctgccacatcagcagaaggtcac ctcaacatgtgagctacctccccggagaccccccagatccgtaaggatgatgcatccttgatcctaaaaacattttcctg ttcctggtgttcagaattggactccacactcactggtctctttataatcttgcttctggccctttgaggcctcaaagcta ccagggccttgctgccaggggacaatcaccgctcccggctgagtcctgcagacatagggcctgggctggctgcctcctcc tgctggcccagcatcttgcttgcactaaagagagctggaggcttggcactgatgcttgctaaaaacctacccaggccgcc cactgctgccgcactgcagggcaccagcccacactcctcccctcctggcatcaggcacacgttcacggcactaaacctta caggaaagcagtggaaccctgtctttccttcacaggaggcactttccttcctaggcaaaaacgatgatacccatgggcac agcatctcacatagggacacatagagatgtctgactcattaaaacccaagtctctggccaattaaaaggggtccttaatg tcctactcaacagtggtggaaggaaatttgctctatattgatgaaatgaggtggagaaaatctgattttccaaacatgag aattctccatatgccaccccataaccaaagaccccttatttgtgttagatgaaacattcaaagagcctattaggatagcg gatgagacccccaagggacatgcttatacaacaataactggctccaaaccacactccatggcagtggctctcaaatgcca gctcacatcacaagccctgtgctaaaacacagagttctgggccccatcccggagtttgtggttcaggaggtctggagtgt gacctcagaatatgcatttctaacaaattccccaggggatgcagatactgctgacccaaggccctccttctgagaaccac tgttccagggagaagaaactcagctaagtaagggtttggctttgtgctgaagacaatgtggaatttagagttggggtgaa ttattcaggaaagtagagaggtttggagatgtgagggtgggaagcgcagtggagggaggcagagaggaaatatgaagcag cgtcagttggagagaaattaggaagaggaataaaatgatatatgccagggatttcagttttgctgagcccatgatgacag actcttctctggcaccttatgccactcattgagggcttgtagctggctctgctctttcagagtcataatagggctatggg tctgacctcaaggtgagctggaatgggcacaagtaatagataaaactgcaagaagtcactcaagggtccttcctagaaca aaggatccctacattccaaaggcgaatgccggtcactatcataaaagaaaagaaagaaagaaactgatggtgacatttta aatggcaatttttctagcttctaaaaggttgtggagcaactggaactttcataccctgctggtgggaatgtaaaatggta taatcactttggaaaaattggcagtgtcaccaaaagcaaagcctatacctactatccatttcactcctcagtatttaccc aagagaaatgagcatgtatgtccatacaaagatttggacccaaatgttcatgacagccttatttatatagcctcaaacta gaaaaagtctgtctatcaacaggtgaatggataaacaaatactggcctgtgtatctaatggaatactgctcatccacaaa aagaaacgagctattgatacacacaggagcatgcacgaaatctcaaaatgctgaatgaaggaggccagattttaatttta tttttaattatttatttatttatttatttttgagacagagtctcgctctgtcacccagcctggaatgcaatggtgtgatc ttggctgactgcaacctctgcctcctgagttcaagcaattctcatgcctcagcctcccaagtagctgtgactacagtcat gcacaagagcaactgactaatttttgtaattttagtagagacggggttttgccatgttggccagctgctctcacactcct gacctcaggtgatccacctgcctcggcctcctaaagtgctgggattacaggcatgagtcaccgtgcccagccggaagcca gatattttttaaaagtacttattttgtgattctatttatataaaattctagaaaatgcaaacaaatccatagcgacagca aatcagtggttgctggagatgttggaggggagaggagaggaatagattgcaaaggggaacaaggaaattcggggggacag tggatatgtctgctattttgactgtggtgatggtttcattggtatatacatatgtcaaaaacgtaacaagttgtatacgt gatttattatgtgttgactatacctcaaaaaggctattttttaaaatccccctcaggctccaggcactccattacgttgg tgtgacttgtcttggaaatatactttgagcatttgccggaggagatccagtgcctgggcctctgtttcttctcccaagta gaattggcagctaaaacgggatgcccatgggcacaacttgtcacccccatcaccgaacagggagcagaaggaggctgctg ggggtgcccccacagggagcacagtctcatcgggaatgacctgccatggcaaataaaatcaccagggcaagtcaagggag agaccagggaagagagtgatccagtctatattaaaaaaggatgagaaaggttgaagaaaaagagaagaagggacagaaat tctcttcacacatttgcagaagtaggtccggactctccatccacttctcctcctccgataggtaggacaggaatctcaga ggaaatggcatcatcttcccatgtttacagacacagcaatgaactcaaagaacaatcttatcaggattttccaaatgaaa acatggagcatatagagaataaagatccataaactcgtatggtggctgagactgaaatggttaatgaaaagcaaaagtgt gtgctgaatgacaccagccacaatggcctgaacacttaagtagtgtaatatacttggaacattgacagctaacaaggtct tcctcccatgtcagaccaagaacacagtttcctaaagataaaaatagcacatgcttttccacttttccataagtgactgc attagaaaactaacaaaccatgaaaagcaaaatatggctagtctcttcaagaaaaactggtgtttctattttgtctgtaa attactttctaatacaaaaaacaattcctgttacattgaggtaattctaactagggacatatgagagagagattgaaatc tcatgagctgtctccttttcatctcaattctgtgtactcgtgggtacaaatggaactagtttttgtttgtttgtttgttt tttgagatggagtcttgcgctgttgcccaggctggagtgcaaaggtgtgatctcggctcactgcaacctctgcctcctgg gttcaagcaattctcctgcctcagcctcctgaatagctgagattacaggcgcctgccaccatgcctgactaatttttttt ttgtttgtattttttagtagagacagggtttcaccatgttggtcaggctggtctcaaactcctgacctcaggtgatccac ccacctcggcctcccaaagtgctgggattacaggcgtgagccactgcacctggcccggaactagttttaaaacaggaaac agttgatatactgaatggaaaaacaatacaatttgaagttgaaaaaacaaaataagatgcccagttaaatttaaatttca gttaagcagctaatagttatttagtataagtacaacccatatacgacaattgcagtatttgttatttatctgaaattcag acttacctgggcatcctagtatcctgttttttgttttgttttgtttttccctttgttttcttttttttccccgaaatctg accaccttaactttaaggtatttattcatttttaaaaactaaatatttttcggcagtcagaactagagcaaagataaatg a cccaggactctgtttagcaggcagtcaggaagtgtgacagtgtggtgggtggcagccccggccaggcctttcctcttc cctaaactgccacagcaggactgccacacttgggaatcccagtttccatctgagcagcccctccagagtttggaaggagt cagtgctttagcctgaggagccgtggatggctctaacactttgcttgtcggttgaataaaaatcaacccaaaggtggcct acactcattgaagtaggaatgccagaacttcagtggtgtcacatagaagaaaatatctaagtgcttagggagatggcagt gctagtggatctactggatcattaagactcactcacccacccagcgcaggtctagaggacacacccttgccacactggga agtgtaaatgagctccagcatctttatttttttttattttttatttgttttattatactttaagttttagggtacacgtg cacaaagtgcaggtttgttacatatgtatacatgtgccatgttggtgtgctgcacccattaactcgtcatttaacattag gtatatctcctaatgctatccctccccccgcccccggtgtgtgatgtcccccttcctgtgtccatgtgttcttattgttc aattcccacctatgagtgagaacatggggtgtttggttttttgtccttgtgatagtttgctgagaatgatggtttccagc ttcatccatgtcccgcatctttaaaaaaaaaaaaaaatctctaagtggtggctcttctctgtagatcaggagctgtagtg agcaatgctacaaaactggagtttctaaatacaggggggatggtgggattctgaggaaggacaggccacgtggtaacact tacaaaagaccaagtgggtgtggttgccactgtggacggtggagccaaagcagtcctcagaatagtctgacccccagagg tctttggcattggctggttgatcatggtgtccctggaattgaaatagaaggacggtctactaaatttttacctgatctgt ataagcagaagagttctatctctagtgaacagaagtctaactttagtcaccagaactgagagtcaattcaatcaattccc

' agatttgacatagtttatagacctagaaccccttgaatgaaaggtaagctggctccccttgaggaaggaccctgttacat ttccggcattttattctgataatcttttttcccagccttccccaaagcaacttagggccatttaccagggaaagccatgg aggaaaaggaaataattaggctatttggagattccaggacactggctctacgctgacaccagttctaagagacccaaaat atctttgtggtctaccagccaaagtagggcttcatagaggtcaggggtcactagagtttgagctcaggtctgtttcactg tgagtctagagggtccctgaacttatcctatagttattcccccagttccagaatgcagaattgagctgagagcagtggct catgcttgtagtcccaacactctgggaggcgaaggtgagaggatcacttgagccaagcggtttgagaccagcctgggaaa tatagtgagaccccatcttttaaaaagacaaagaaaaataaagaaaattgacatggaaaaataatataaaatgtgaataa tctcacatctactaaagaaattcaatctgtaattagaactcctcccacagagaactataagcccagtgcccccatcaact ggagaaacagaaagaaacaatcttcttaacagaaagcataattggaatagagatactctgcatcggggaagaatccccat attgattctctgatccatagagtgaaggccaagtggaagcctttggaactccctctacctgccaagatactaaacaaaac aacactgcacgtctggaggaattgtagcaagaacttgaaagatgaaggatgatgatgtccacctctctccattcagctca cctatctggtttgtgcagaagacaaataggtgttggaaaatgacagtggaccagtgtaaacttaatcaggcgggggctcc agctgcagctgcaggatcaggtgttgtttcatttctgcagctaatcaacccttctcctggcacctggtgtgcagatggca atttttcttttctattatctgttagtaaagactatcagaagctgtttattttcagttggcaaggtcagcaatacactcca agggaagagcagtctgtctcagatcttaccgatgcctggggatagggagggagtggccccctcaccgtctccaaggccta gtcctctgctcctgctactggcagcaaatccacgcaggtctgcaacaacctcaattcctgcctcctcagaagaaagaatt caattgagggacgtaagacagaaggagagactgaggcaagttttagcacaggagtaaaagtttatttaaaagctttagaa taggaacaaaaggaaggaaagtacacttggaagagggccaagtggacgacttaaaaagcaagtgcgtggtttgacctttt gacttggggttttatacgtcagcatgctttcggggtcttgcgttatttctcccctggttcttcccttggggtgggctgtc ccatgtgcctgcctgagcccactggctcaactcctgagatcttatagggaaactactgctcaccagtttcgagtgttttc tatctattaggagccggcttttccctgttgccgggtgtgaccaattattactttagaaagacagtcaacaaccgccagac catcacctgatggtcacctgacactcctggtgtgtggggtatggggagccctctcctgccctgctctttctgactagcta cccactataacactcccagagggacctgcacattttgtgctctttgcaagacagtgcctgcccagcacctgtaggcctgc tcaccccttcagggtcatgatttttgctttttaccgcaggtacccataagcaaaacatggcattgttcaccatgctttta cattattcacataattttaagttatttacacaacaatgtaaaaccatggtgaaccatgccacatgttgcttatgggtacc tgtggtaaaaatcctgctactagctcattttgcagtgtctataatgacaggtaatgctccattcactcctttatgacact tgcaaaaactgagaacataacgcctcccagttaagcaggcatctgggcaatgtgaggagaacagaaatagaccacgctgc atttatctctcttgatgacaggcattgagatttccactttttctggtttcttattatgtctctactgggcattcttacat acatcttgcacgccatggaaagtttctctagggcagtggttcacaaactttttggatacagaatacttttatgtgcttga aaactgaggaccccatacagctttagtttatgtgggtgtaaggttctagcccaaactgaagtccgaagggagttggtggg tgggtgaggggtagctgaaaaaacacccgaggaatcataggcagtttgaacatggccttatcctctctctgggcacgagc catatgtccagtgtcagcagggtaattataccttttacagacaatagaggctctgaagcaatcacgagctcacgtgagtg gtcacctaatgcacctcaagtggcatggttcataatgtgcggagtcgtgtgcctacgctccaaacccactgagtcatggt gcaccaaaaagtggcctcagcctgctcctgactaaagcgcagccatcttccttacactccacccctaggccaggggcatc ctccaggtagggacatgtgcccgtagggtggagccctgaatccataatccacagcaacaatacggagagcaacagc cat gactaggattccagctatgctacttatgactatcagggcccagcgtaggccagagcccagggatgtctaccatctctgca gggggtcatcagtaaggctcttgactaccttaatctcctgtgagaccccttgcagggctgctgttatgttctgccaattg tcagggataaaggtacaacattgtgttcctaaaagggcacaggtgcctccttaggcagcagttactatgtctaagaccat tcggtttcgcaacaccacctttctgatctgatcaacctcatccattaatgggaagagggccactcaggtgtaattcagag cctgagcagcatgctctgcaagagcagtaacttggcttctacagttgtgacacacactccagggctagtgcctgtcaagg ggtaaaaccaccagggtgctcattacacttgcaaaaaccgagagtgtagcacctcccagttatgcaggcatctgggcaat gtgagaacagtggcaggtacatgaggccaccctcaggtataatgtccagtccagtttgcttataggtaaggccaccctgt gtccccacagacccataaactcccagggggcacacagtccatcgaggccccttggtggggccgcgtcttccaccatacct ttggtgtggtgacatgtattatgcttacacacactgtgacgggtacccatcccacagtgctattaccccagtgttgctat atgcaccacagtgcctgggccaggggtactgcacgttacctcactagccagccccacccatcataaatgctatgggccag ccagggaatggctgtgctgtgggtcttgtggcatcctttgtccaaaacttgccacgttgcgttccaggcatcagccatgg gaccccaagtctccagccatgtctggttctctgcagatgctgaatgtatgtgctaaggcaagccatctgcagctgctaga agggcggtgcagatccaacagttggaaacattggtcacttcagtgtaggtgtgggcccagtccacaatgcagttggagca tgttaacctacagttggaatgacagagtaggcataggtactaacagaggaaaatcacatccctcaggtaaaatacaggct aacctttcatccctggataacaatgcagcccccaaggggttctgccctgggcaatagtaccacaccttttcagctcccca tggttcctttgggtcctgtattcatgcgaaagtcacaggggagcttgtagtaggccacacagacagtacatttgaaccct ggaggaaagtttcttccctggccgttttcctacaaacagttaacttcggggaccattcattgaacacccaaagagtgaca tacaagtcatactgtaggccctccccacagggagctacgatggacaaccaccagcagccgggggcttggaggggctatgg ccacagccaggttttctgttcccctgccttcagggacgttggggcaggcaacaacaggttactgttcatccccatacctg gtcagaggcggttacccttggtgtgtatctgcaactgaataggggtggtggcccatgtaacaaagcctccacctgggctg ggctgcttttccatggccattcattcaaggtttggagcatcaggtccagcctggaacttcagccctgcaaagacaggagt gtgacatgcaagtaaaacccattcttcaagagctcgctatatcactcaatcatacccacagcttgcaagttgtgcggtac atggaatccctactttatgtccattgttgtgcctgttgtccagtaaaatgtgtcccccatcactctcaatgaccaaaggg caaccatatagagcacataagtgttgcagggtctggatggtgtgctgttggttggccaccctgcaaggataggcaaacaa caggcctgtggctgtgtccacagctgttagcgcatgagtatacccttgtgacttcggcagcagcccaatgtagtctactt gccacctggtcaagggcacttgccctgttgtcacttgtgtagcactggacagctgcctccatttagggt'atgcctgagca catgccgggcatttctgacaagcctcccaaatgtcttgcatgggcagagacagaccccaacatttattgacttgttgcat cagtttaccccctgcatgtcccagtttccggtgtagctacaaggccacatctcatgtagatgccaactctaaccatcgga ccttggccaaggcttctgcctcgtcattgctgggggtggccagaggcatatggcctgacaaatgataaatagttacatct ttgcaatgacccatttcccagaggtcttgctacatgggttggtggccccaaatgggttggtggccaactagccaattctg tattttccaagtagttaaacacaaagttaggcctccatagactgcccagctatcggtacggattaccataggtgtctccg ccttgttgatcaccatccatactgctttaaattcagcccattgactactttgtccacatctggtttcaaaccatatggtt ttggtactaagttggactgcaacactggtccaagcaggagtagcacctcgactagacccatctgtgtgccatgccccatc aggaatagagggatgcccttccttaaatggcagtggctcagggtcaaggggtgcctcaggccccatggccttctcttgca ttaggactgcaggtcccaagacctcttgcaactctgctgctaatgggcttgtgctcagcgtactctgttgctccaagtaa gtgcctcactttgccaaagtggatgtctgcaccatcccagtctggggggtcattacacatgaatgcacccatcccgctgt caggtaagtcatccacactgtgactgtagcccatcctatcacttctcacaagcctgaagggcagcatatacagctgctag ctatttctcta caaggaataccagagctcagctcctttccatagttgggaccaaaagcctcctggcattctcaggcact ctgtgtgctgccacaggcccaaactaaaaccatctgtggtcacatgcatatccagttcaaatgggcaccccttgtcaaat acccacagggctcgtgcctgctgaatagcccacttggctgccaggaagccagtctcagccacatcagcccaatcccagat tgctcccttctttgttaactgatacaatggttttatcatttgagctaaatgaggcaggaatgtccaccaatatcccagga ggctcacaaaagtttgcagctgcctcaccgtggtgggccagggatatgcctaaattttgtcaatgatagcctcttgtatg gccttcatcttacccgaccagataactcccaagaatttagcaggtaatccaggccctcggaccttggatttgttgatggc ccaactgcatgctgccaaatgttgccacaagaggggtgccactgcttctaaatctgcaagagaatcagaggttaacataa tatcatcaacgtaatggaacaagtggactccctttggacattttcaggctgttaaatccatggcaacaagaccatgacat atggtggagctatgcacatagccctgcagcaacactgtgaaagtccattgtcatcaaggcaaactgttcctggctctcta gagcaaggtcaactgagaagaatgcattggccaagtccaccacatagtggtactgtcctaattccattgtcgagtggttc atcaaatccatgatagatggcacagcttccaagccatgtaaaatatcσacctccagaatgtattcaggtatgggagagac atacacagtgtataagcaaggagccaagtggccaatgccaaggtacagagatacaggtttcactttcactgactggcctc cgtaacctttaatatatgcagatttgcccaaaaacttaactgggttcccataaacaaggctacaatctatgccagtatct accagcaccagcacccactgtacattggtgggggaccagtggattgccaattccacatgtggcctctggtcatctggtgt ccccccaagccagacacctttggccagttccctagttgaacagaaaaggctctacatttccacctggctgcagcaagtag tctctgagctgggtaggaccaggtcacacagcaatgcctttctcccctttgggcattttccggaattgctgccctgcata caactgtctccgcaaagttaggagtatttcattgggctgcttatcaattttctctcagtcaaccccagccaaaatcaaat ctatccacatctgtgagcgtgtcactcgttggggccccctttttttatgggggagccccctgtgggtggggtaacttccc cttctttatggtgtggaccctccaatccccctgaaggccttctgcttccctgagagccgccatggcagtggttacttcat gtatgcggtgccctacgtatggggtgaggacagcagctagggagccaaaggggctcaggagcatcaaacccaacatgaga tccctcatgtgggaggtgaaacatttatcatctggccctcaggtattcaggacaaacatagcctgccgcatacccatctc ccgaatgacttacaccaaattggcatatgactgccatttactcacagttttgggcatttcaccagcattattccacacag ttcatatggctgcctgtagccactcagtcagggtgtggtctccttgcgctgccactaaccacctgctcacttgcagccgc tgacagagagaggggtgagtcatggtggaggccagcttgtccatctcagaggtggaatgggagataccatctgctccctt gt ccacagacgaagcatccaggcaggcaggggttcccctggacactggcaacactgcttgcctaattcctgcaactcag ttggggtacaggcaatatacgaaatgtgttgcattatggtggggagtccctgagtccacccttggagccccagtggctgt tcatgatctaccttctgtcagaccaccgggtgagcccgcaacaggggttcttcctccttggtatgaaactgagtggggat ctccagacaagatgatggacccaggcctgcattcatggtagcctctaattccttttccaagctctgaagccacacctcca ggcatcctgcctgcacctggaggtccccattcatggcagcctctaattattttccagatcggtgtagccagacctccagt ctgcatccctcagggactgggtgtgtacttttcttagcacagttaaaaatgcccatccaactctgccagcaaaggctctc tccttcttggtgctctgcacttccagctgcttcagcgccttctccatgctcatgggggacccatctactgccacccaggt ttccactcaagcccaccctcacagcacggctaccaccgggtaccacaacccatgttgtggtcacatggccaacctggaat cagcagggaccgaaggctcacttaccttaggatcctgttcgtgatgccaattgtcaggttctagσccaaactaaagtcca aggggagttggtgggtgggtggcaggtaactggaaaaacactcgagtaggcggtttcgacatggctttattctctctctg ggtgcaagccatatgtagtgtcagcagggtaattttaccttttacagacaatagtggctttgagccaagcacgtgctcat atgagtggtcacctaatgcacctcacatggcatggttacataatgtgtggagttgtgtgcctgcctccaaacccactgag tcatgctgcaccagaaggctgcctcggcctactcctgactaaagcacaaccatctcccttagagtgggctaaatctactg ctatttatactattagaaattttaacacagaagttttaaatatttacattgttaattgattttgaaataataagcccatt acaggttaacataattaacatacttttattaaaaatatctgtattttttaaaagaaaaaaaattagcaacaacagtgatc cttggaatcgtcccacctcagcctcccaagtagctgagaccacaggcgcacatcaccatgcgagctaatttctatatttt ttggtagagatgggatcttgccatgctggccagggtggtctcgagctcctaagctcaagtgatcctcctgcctcggtctc ccaaagtgctgagattacaggtgtgagccaccacttctggccagaagctggattctctgtcttgttctccatccaatctg ttagactgtcaaatgccaaataacctttggaaaattctactcgtaaaataaggagagagataaataacttctgagtatca tcattaaaatagtttgacctcatggacccactgggtcccatgtggagaatagctctaagctaaagagtagaatggctggg aggggacataaacattcagcccatagctgctgaccacaataacacattttaagtctcttcctctcctgctccttgtgatt gcagacagactcaatctgtaggagagctgtagagagaacaagctcaagcccctgattttgcctacaaagaaagctgagcc cagcaaagttaagggacttacccaaggtcacacagccacacagcagagctggggctgagctccaggtgtcctgctacaga ggccacttctttctcccactagggactggcctgtgattacttcagaaaacaatggtcagctaactgattctgaacgccct ttgctggtaaaagctaatctcctgaggaaaaatgtatgcattggctgggcgcagtggctcaagcctataattccagcatt ttgggaggtggagacaggtggatcacttgaggtcaggagtttaagaccagcctggcagtcatggtgaaaccccgtctcta ctaaaactacaaatattaagctcggcatggtggcaggcacctgtaatcccagctactggagagactgaggcaggagaatc gcttgaacccaggaggcggaggttgcagtgagccgaggtcgcaccactgcattccatcctgggcaacagagtgagattct gtctcaaaaaataataatagtaaaataaaaataaataaacaaataagtatgcatcacctcaggtggtcagtcagctttcc caagaccccaaagcacacaatgttctttctggtatgagtgacatggggttcacagcaccacaaagtccatgacttttccc tcagaagtgaatgcatggctaattattttgtattttttgtagacatggagttttgccatgttgcccacgctgctctcaaa ttcctggactcaagtaatccacccacctcagcttcccaaggtgctgggattacaggcatgagacaccgcatggcctgcac ctatagtcccagctatcaggaggctgaggtgggaggatcacctgaaccggggaagttgaacctgcagtgaactgtgatcg ctccggtgcactccatcctgggcaacagagtgagatcctgcctcaaaaaaaaaaaaaaagtgaacacacatgctggggaa gaggcctgcaggcacccctgccagttctgcaccagagcacactgtagcagccctgctgtgatgcaggaagcagctccagg tcctgcagtctgaagcatggagcctgaagcctggagccccccatccaatgctgcgccatgctcaccagtatcccccagca tcagcaccgaggcaccagctgcagataaatttctcacctaaaatgttgagagatgttgctaaactgtccttctaagggta tgtataataatacggtcctgccgatactgaataagactatctgtttcattacatcctcacaatactgaatatcattagca acttgaattttaaattgtgctaatcaatgaaaatgattgcctaattactagtgagttgaggttatttaacattaatactc cttctgatgaaatattttgcatttatcacattttacataaattctctctatataattagcactagaatgtccgacttggt tttcattgttcctcacctgtttggaaacacattaagaatgagggagagaatggatggggactcacctagggatgcatgga gctggtcggcagccactctgaggccctcttaacacttccccaccacacacttaatttcccctggtttgtccatagataca tccaacaatttttatgtaaataagaaagactcagctttcaatggaaaatggtaggttggattttatgactgaagtggcaa aaagaaataagggattttattatgggggaggtccaaaccctggtgaaaaacgaaattcattgaaattgtttgaaaattca aggattaaatcagattattttggattcagtaggaattagattactttaaagccccaggatactttattctgtagaatgca tggaaagtatagaaaagagaaacaaagagggaaagtcatggctaataacctggaaggggtaaatagggagccaaaggcct gtgggacgtaaccaactcagcattccactggaggctttatgatcaaatagcaagctatttatcatgaatgcaggatgtgg gcaaactcacgactgctcccactgccagaaggtttgctgagggcaatcacttcctggcaccgagctccttgaggttatct actgggacatctggagaatgcagtcttgcaagcctactctggacccagcagctgaccccttcttccatgcccctcttcct gctatctcttttgcctaataaatatggagggctgtgtaaagctcagggcccttgtccactagaggcaaactgcccgctga ccccttcttccaaatatgctcttttgtctcatgtcttttattcccgctttcaccccactttgttcagtccccctagggcc gtgtgggttacatagtggcgccctgaacagcgacagaatcaggtgctctacaagtggcgtccgaacacagggactatgag gatgtgaatgaagaagatctgctggagcagaggaattgaaattgacaaggtgaatggggatcccgggacaagtctgccgg cagcagatataaggtcagtgccctaaagaggtactgggagcagtgccttaaagtagtactgggaatgggaagttttctga atcagggtaacatggggcagaattggtctgttgaagaaaaacattatgtgcagttgcttaaagttttgttgaaacaaact ggtgctcaggttagttctcacattaactacgatgctacaggaagtcattatgcataacccatggtttccacaggcaggga ctcttgatgtagaaaattgggatagagcagaaggattaaaacaggctcatcaaaaaggttttcaagttgattcttcagtt ttctccacttggagtttagttcgtactgtacttctgccattatctccttgttattctgcgggacagcaggctgaatgtaa aaatctgaaagaatctgttgtcccacccacagctccagttgaaaataagtaataggagagggaggataaaaattggccta taccgccccctccagttgcagaaacatctgtaccgcctccttcggtggcagaaacagagaccccaatacaaagaatttta cgctctgccgccacggctggagagcccttaggaccttgcacttttcctatttccgtaagtcctgatccaaataatccaca gcagcttaatcatgaacacattccactagagtttaagttgttaaaggaattaaaagtgagtgtggtaaataatggcatac agagcccattcactttaggattgctagaatctatgtttggtgctatgtgtcttttaccctttgatgtgaaacacttggca tgaacttgcttgtctgctagcgcatatctgacatggaatttaaactggcaagaacagggtgcagaccaggctagacagaa ccatgctgctggaaatggagacattacagaggataggctattgggtaatggcccttattctgacctggtacatcaactag cactcacaaatgctgcttatcagcagtgcacacaggctgctaaatgtgcctgggccataattcctgaagagggagtccca gtactatcatttttacatatcatgcaagggtcacaggaaccctacgcacaatttcttgcaagattacaagaggcagtgag gcatcagattcctcataccttggctgcagaaatgctaacctttactctagcttttgagaatgcaaatgcagattgtaaat gtgcactggcaccggttaggtgtacaaaaacttgggaaattttctcagagcttgttaagatgtagcaactgagctttatc gatctgcaatgttagctgaagcaatggctaatttagctgttgacaaatctaaaaagagccaagggtcaaaccctaaaatg ggaaaatgttataattgtggaaaaactggacattttaaaaaggaacgccaccagatctcaggacagaaaggatcttacaa tgcttttccccccggcccccagcggaaagaacacctggactttgtcctcgctatgacaaaggaaataactcggctaatca gtgctgctcaaaatttcatcagaatggcacccccctgttgggaaatgagatgggggcctgtacccgggcctcacaaacaa tgagggcattcccaattcagacctcaaccctgtttcaggcatgggttcccagaggcatattgagtccctcacccgaggaa ctccaggaagtgcaggattagatctcccagccagagaaagggttacataaggtggggaagacaaacccaccaagattctc actggcatttggggacctttaccagcaggatatatgggactaattttaggcaaaagccaccttaacttgcaaaggcatta ctgtagtcccagaagttgttgactctgattatgaaggagaaattcaagtagttttattgtcacgagatcttcgggttttt gaaccgagagaatacataatgcaattattacttattccctgcaaattacacccttctccatgaaaggagaaacaaggaaa taaagggtttgggagcacagctacacgggaaatctatctatcccgacccatagcctctaatagacccacctgtgtagtac aaattaaaggaaagaaattttatgggtttatggataccggagctgatgtgtcagtgttaccagcaggtctttgttcttag agctcccaagatggcggcaagccttttgttctctgacctggagttcttggcctcacagattccaaggaatggatccttgg gccatgcagtgagtgtcatagctctattagaagctcttccaaaagtcgtgctgctatctatggactaaaacatactcaaa caataatgacctctggcgtttaggctcaatgctcagagctaattgcagtcattcaggttttacagctcacagcttcagat cctgtcaacattgtctgtgttcagtttatgtcgtaaatgtagccggtcacatagaaactgctacaattaaaagtacgcta aacccagaactgctaatttatttttaagacttcaacaagttatttgttctagtgcagctccttttcatatttctcatatt ccttctcacacacaacttcctgggccgctatctctaagtaatgagaaaacagacaaactgattgcctctgtgtttcagca agctcaaccatctcatgtgcttctgcaccaaaatacttccgcccttactcacatgttcctacaggtttgtattatattat gcagtatatccctcgagccacacctatagaaggatgtaatccacgaggtttggctccaaatgaaatctggcaaatggatg ttacacacacagcaacctttgataagctgagctatgttcatgtgactatagacacttattctcatatgctgcctgctaca tgccaaacaggtgagacagctggtcatgtacagcgacactgtctgtcatcatttgctcatatggggatatctaaacaatt aaaaactgacaatggacccgcttatactagtcatgcttttaaaaatttcttgcagctttgggctataacccataaaacag gaattccttataatcctagaggacaaggcattatagagcaggcacatcaaacattacaatgcatgttgaaaagacaaaaa gcgggtataggaggccaactaccacctcaataaaaactacatttagccttatttactttaaattttttgactcctggtat ggatggtaagactccagcagaaagacattggcaagtgttagaagaaaagaggaaaatttatccaaaagtgttatggaaat ccctggaagaaggaaaatggaaaggtctggtggatttactgacgtggggaagagagtatgcttgtgtttttacaggagat ggacaagccgtgtgggtgccctcaaggtgtgtgcaaccatggaacgggagactagaggaacccagggtggccaaccatgg acagggtccccccggtacgagccatgagccagctgagcctgagtgcaaagacggagagaaggccaactggagtcacaaca cagttctaatgttatatttgtaaagaatatcactactcaacttacagtttgtgtttatagatatagatatagatatagat atagatatggatatagatatagatatagttatagatatagatagatatacactttaagttctagggtacatgtgcacaac ttgcaggtttgttacataggtatacatgtgccatgttggtttgctgcacccatcaactcatcatttacattaggtatttc tcctaatgctctccctcccccagcaccgcctcccaacaggccctggtatgtgatgttccctgccctgtgtccaagtgttc tcattgttcaatttccacctatgaatgagaacatgcagtgttttattttctgttcctgtattagtttgctgagaatgatg gtttccagcttcatccatgtccctgcaaaggacatgaactcatccttttttatggctgcatagtattccatggtgtatcc ttatgtctttttgacagctaagaaggaccagctccaggtaaacaatacccaattgacctgtaaatcttaccaattatatc actgcattaatcatagcacattgcaaacacataatatctctactttgatgattttaggccacatccctgggctatgtatt cctgttaatctgtccgaggcttgggctgccacacctgctttgcattttgtgaaacttcttctaactgagcttactcatca tgtctgtagagccttagacataataattttagctattgtttccttggtcgcactaataacttctgttgtgatgtcctctg tagctttgcataattctattcaaacagctcagtacatggagaactggacacacacagccgaccaagcatggctacttcag aataaaattaacactgagttacaaactgaagtggtgttatgggaagtcagggaccccaaagagagggaccagctggagcc acagcagaggaacgtaaattgtgaagatttcatcttaatacggatatttatcagttctcaaataatacttttacaatttc ttatgcctgtctttaatctcttaatcctgttaccttcgtaagctgaggatgtgcatcacctcaggaccactgttataatt gtgttaactgtacaaattgattgtaaaacgtgtgtttgaacaatatgaaatcagtgcaccttgaaaaagaacagaataac ggtgatttttatggaacaagggaagacaaccataaggtctgactgcctgcagggtcgggcaaaaagagccatatttttct ttttgcagagagcctataaatgaatgtgcaagtaggaaacatatcgctaaattcttttcctagcaaggaatattaatatt aataccctcggaaaagaatgcattcctgaggggaggtctataaatggccgctctgggaatgtctgtcttgtgcagttgag ataaggactgagatacgccctggtctcctgcagaaccctcaggcttactagagtggggaaaaactctgctgtagtaaatt tttggtcagaccagttttctgctctcaaaccctgttttctgttaagatgtttatcaagacaatacgtgcaccactgaaca tagacccttatcaggagtttatgatttttctcctgtcctgtttcctcaggagcatgtgatctttgttctcctttttgccc tttgaagcatgtgatctttgtgacctactccctgttcttacaccccctccccttttgaaatccttaataaaaacctgctg gttttgcggctcaggtgggcatcacggtcctaccaatatgtgatgtcacccctggaggcccagctgtaaaattcttctct ttgtactctttctctttatttctcagccagccgacacttatggaaaatagaacgaacctacgtgaaatattgggggtggg ttcccccgatatgtgatgtcacccctggtggcccagctgtaaaattcctctctttgtactgtctctctttatttctcagc tggccaacacttatggaaaatagaaggaacctatgttgaaatactgagggtgggttctcccaataaagtggtaatgttga aatccacagttctatggttaggggaaaagcacaaagcttgcaattgcagcagcaattgcattgtcattttaatcacactc atatttgtgtaaccaacttagaatataaccaaagtgagtatctgtgggacgttgtgaaagcccatttgcagggagctttc acatctaacatcacctttgatattggtgaattacaaaacaaaattcttgatttacataggcaaattcaagagtttctgcc ttctttagaagactggaccaaattccagcaaggcctggagagcctcaatccttggacttatctaaggcactacattaaca tcttacatgtagttcttggaataatattgttttgtctctgtcttctgttcatagcctgtaaaattggatggaccaccaat cggaaaatgagagctgcccaccctggccttacattctttcaattaattcataaacagaaagggggatatttagggagcct aaggctcgtgggactgaccaactcatcattccactggaggctatatgataaaacagcaaactgtttatcatgaatgcagg atgtgggcaaactcacgactgctcccactgccagaaggtttgctgagggcaatcacttcctggcaccaggctccttgagg tta ctactgggacatctggagaatgcagtcttgcaagcctactgtggactgagcagctgatcccttcttccacgccccc cttctcactatctcttttgtctaatcactacggagggttgtgtaaagctcagggcccttgtccactagaggcaaagtgcc ccctgaccgcttcttccaaatatactcttttgtctcttgtcttttattcccacgtttgccccctttgttcagtttcccta ggtccatgtgggttacatagtggcaacctgaacaatgacagaatcaggtgctctacagaaataactttttaaggaaagat ttgggacttagagaccccaggagacatacacaaaaatgataagaggatgtgcccaaaccagtcttaaagttgtggcacag ggtgaggaagatgaagctgttactgaacctcagagagtgactggtgttacagcaaaagttagcaatggcctgaagggagg gtttctgaaatcaaatatgaatgattccccctcagggaacccaaccttgggaactactgcatggttctctgtatgggaaa atatcattaatgcaggataaattgtgaaatatcacaggaagcatcctgcatctagtcaatcttctgtttctggggtggcc tgtgcagctgtgcaggcagaggcccaaccatcctggtgagtggcacacagggactgagatccagccacacctaccaggcc atgctctgggaagggggtgggacctgggcaaaggacacctctctaggactgcacagaagcctttgtgggtgggtgggaca ttcctgtgatggccttctggctgggcactatgaaatgctctgaagatttttccttgcactgttgcactaaccccagtcct ctatcactgccccttcctcctgggcgacttcactgatgttgtggccatgtgaattctctggccaatgaaatgataaagat gatatggcctctgccaagcagacactgtaagtattattgtatgatgcttttgtctctttttttaaagttaaagcagttta ttaagaaaataaaggaataaaagaatagcactccataggcagagcagctgcctctgtctcttatattttcccctctgcct caagcccaacatgcccaaaattggggctgctggttcagcctgggtctcagaataaagacatgagccacagatccattgct gacccatgatggagatggacacaagagagaaacacatttttgtcatgttagccactaagattttgatttggaggccattt gctacagcaatataacctagcgtgaacagagagacacagcgatgttccatttcttttcaacctggaacaggagaatttca taggtgggcctcaatttcactttagtatcttatttagacaagaaagttcatactgttcaaatgtcatgtttaagagtgct ggcattatcactgctgtggctaccccatcagatgttgctcactgactaatcttctcatgttagtgaggatggacaacata tcaggccataattcaaagtagcaaataggaaaagagcttcatcctagcattatgggaccttaattaatgtcctttcctga caggtttcagaggcttttgcaggcagcagcagagctattcatctcactgacagtggggaacatggccaaatggttgcccc cacaatggaggcagagtttcaggacacttgtctgatctctgcccttgaaggaacagtctcaccctgattgacacttttgc ctgttatgtccaaagaaccaatggaaaagcaggaaaattattccttcttcatttctctcttcattatttaaaattattct gtcttcacttctctctccttttctctgcttcctacttagctctttagaaatgcaattataatcttttatctccccttcac cagacactcccaacagggcaagttcatctaactatgtgctcttagttagacgctacagagcagaactctctcccaccaag agactaccttgagacataacagtcaattcacaagccaaaatatgcccgctatgaaactctcccatctggaaattttttgg ctgcttttacaacctagttttgcccacaaaggcaccagcagtaaccaactcaactgcctggtagacaaggcaccaaagcc agtacccagaccctctacctgctcacttcctgccttgcatgccacgccccccatttaaaagcctctgctttctgctccaa aggtgaagcagttacccttaaggaaagaagcctgtacttcttcccctaaggtagctttggaataaaagtcactttatacc aaacctagctcttgttaattagactctgcaagtgatgagcaactgaacctacatttcagttataattcctatgcttgttc ttcctgccctgccttggggacacgcacacactcccaggcacatacatgcacgtgcactgagacagctatgtgaataacca acaagatccccttaggaaaaccggtgcttggcctggccttaaattccagacccttgggcatcatacccaagactgcaaga aagaggaggggctggacctgaaaaacttggaagggaaggtccaactgtacaggtattttgtcaggcatgtgatttcagta taaaattctagaaaagatgagtgacactttataaggagagaatatcaacaaaatttctcattttacttcttgctaagacg acagcagggaattgtaagcagatggatgggcaatccccaccttcagcaggggaggccaaggccccaacacacctggggag aagagctgggggcagtgaatggctgaggctttcttggggagctgggccatcttcttcggttttacttcctgaggaattca caggcttccaggagggctgtgggacacaacagagcaagagattcagaaactgatttcttccattaaaccagttatttaat ccaataaatcaaagagaatactaagagttttctctgcccttctcccatcactgagtcagtgcttgccacactcatattcc cactcccctactcctagcgactacggtgttcaagggagccagagtctagccctcaccagccagggtgtttccctgctctg gcctgagagacacaaccaccctgcacttgtctctgattgaatcgactgtcacattctcaagttcacaagacattggtggt cctctagcttctcccggaatgtgaacctgtttgcaatcatgttcacctgcagattcactcattcattcacagatccttac tgagcacctgctttgtgtgagttgctgtgctaagtgctggggacacagcatggatagactggcctgccctcaagaagcat gtggtctatgcagtcctgagctggctgctcacaagaagagccctgtagccatatttctcagagggtggtcctgacctgca tcacagtgacctgagttgtttgtcaatacagaaaagggtttctcaaccttggcactattgacatttggggcctgataata accctttattgcagggggctggctgtgctttgtttagtagcatccctggcctctacctatttgttaccagcagcaccctc tatgttgtaagaatcaaaaaaatgcttctcacattgtcaaatatcccctcaggggaaaaattgtctctcattgaaaacta ccgataaagacatttctggccctgcccccatccttggaccaacagcatccctaatgcccccaactctgggtgagggacca ggaataggaatctgaatgattgcagtgcacagggagctgtgcacactgaaatcccacagttatcaccgggagccttacaa tac ctgtgatgtcttctaaatatttttaagggattaaattaatatcaacatatttccctggttaagatgtgttttccta cacttgaatttttttgagattttgttttctctatagttggcatctatggtaactgtctagaatcagattttttttttttt ttttttgaggaagggtctttcggtgtcacctaggctgtagtgcagtggtacaatcatagctcactgcagcttcaaccttc tgggatcaagcaatcctcctatttcagcctctcaagtagctgggactagaggtgcttgacaccacaccaggctaattttt aaaattatttttgtagaacaaggtctctctgtgttggccacattggtctcaaactcccgggctcaagccatcctcccacc tctgcttcccaaggtggtgggatgacaggtgtgagccatcacacctggctggttttgtcatttctcaatgcatatgtata tatgcacctttcattttactgaataaaatggattatcagtttccaaagatttcatgacagtgccgtcactatccgtacta taaaatttataaaaatttattacatactgctctattttattctctaattattttatcaatgagattataatttcctgaac tgtaaagagatattatctttccttaacatttttacacctgtgttcgttcctagaatgctgtttggccctcaaaccttgac cttcacccatggtggtttctcggggatgctagctagggtctacttacgggaggttgagcactttttcagattagtaatgc ctgcgacatactgtggtcccaaatatttttcatatgttgttttgccatggagtctggccagacactcagtgttgtcattg aacagaaggtttttggtttcagactggaataagcaaaacttgtccgggcagtcagatccatttctcccaaatttagcctg cgacaaaagggcagacagtgagtagctaaggaaaagaggaatttgtgggttaaaggaggcaaaggggtatttcttccacc caagaacagccctgagaaaaccatggggcagaaggagctgagttctggagtcattccacctccttagtggagtcccccac cccacactcctggtggcaggcccgccttgggcagcatccaggcctcacaccacttctggtcctacctcctaccatctgcc atctttccttccttcttaacctgtgaccttttcccatacaacttcttatgggtgacaaggcaacaatggaggggttttga gatctgccctcacaagtcaattgctcaggacattctaatatgcagctcttctagagaggcaggctgctaggaaaacccag gctcagccactaaccagctcagtgtgcaggtcggtcaccctgcctccctcacacagttcctgctctgtcccaggctccca tgtggggagactgagacccaaacccctcagtcacggcagctctctcaccagcaccactgtgtgtgcacattaagagctcc ataaaggccagttatggtggccagtcttgttattcctgagttgttttcttcaaaagcacacagagacatgatgttatatg ataaaaatagaagttctaataaaatcccagattttaagaaaattttgggatttcgttcaaatcacatttagagagcccta aatctatagggcaccttctgagtttgctgttttagaggcctggtctagagcactgttcactcggcccaggttcaggaaat gtcacctgagtaaaaagcactatactaatgcatgtgggaggaaggctcagtggcttcctcatttgccagaagaacagcag gagggaaaaagacagcctctgagccaggcagtgatggcaacaaggccagggcacagagtctcagcagaaatggagtgagt cccagaaagcccagagtcaaaagcctctgttgttcttgttgacactctgggcaacgccacagcatgaagccaatactctc accatgagcttcaagtagaggactagagaggatcgagtgggctggtgcacctagctctgtgatctcctcacctaacatga gcccacacagctaagaaagcactagaagccctgtggtccatacctgttggtggagcaacacctgtttcaggcgttccacc ttatccatccgagacaccacggcatgattcggggccatggcaagatggcagcttctagcctcagtcacaggcttccgttt gccatcgaggcacagcagcgcaaagtctgccagcttcaaatccttagcccatgcgtcattgttatttcctggggagaaaa agaaggtggcatcatccacgcctcccctgcttagccaagaagtctcttctgggtgggtgtggccattccactgacctccc aaatgcacacactggggttgtggtgatgtgaggaacagagaaggagcttcatcctacacaagctgtacaaacttcaaata taccaaatattagtgctgtgtccatgcaatggaatgttattcagcaataaaagggagtgaagttctggtacatcctgcaa tatgcatgaacctcgaaaacgatgctaagtgaaagaagccagtcacaaaagaccacacaataggctgggcacggtggctc atgcctgtaatcccagccctttggaggccaaggtgggagaatcacttgaagctaggagttcatgaccagcttgggcaaca tagcaagacctcatctcaaaaaaaaaaacccaccacatattatatgactccatttatatgaaatgtccagaataggccag cctatggagacagaaagtggattgatggttgccaatgctgaagaaggatagggcaatgactgataataggtgcaagggtt tctttatgggaggatacaagcgttctagagttggattgtgttgatggctgcacaactctgtgaatgtgctggagatcact gaattgtacactttgcatgggtggattttttagtatatgaattctacctcaataaagctgtttagagttcttattttttt aaagaagaaaaccctccacctatgccatatttttcagtgagttccagaaaaagaatagatggtttacattcaaggagaaa ttggtttctcctccctttcatattcaaatgctattagtgtaaccagagaaaggaaaggaacttttataggtttatcaaat atatacagccaattctaacaaaatacagttgtaaagtaccggagaaagttaaaattaaatttgacatcaatctgatccct ggagattacttcagttaatggcttgtaaattctaaatgtaattgtatgcatgtctatgtttgtgcagatgccggctcatt gttccggctcccgtttgtctctctgctctctccctttaagaaagcactttattcattctcttggattcctctatttgata ttgaaataatttcaaatttacatgtcttgttttaatctctgtcccaagagacactagaaggagcagaagcagaagggaga agtggctgagactgcagtgattactgaaggagggaggccgaaagtggagacagttctttctcaggaaacagaatagcaag tcacctgctgagacttgggggttggaatgctgaagtggggctaaggagacagatgcagattggaaggtagcaaatggctg aggaccaggagagagagtgattgttcaaacattggctggaagattatcttccatcatctgcaaccacctgtaattttgtt cccactaactcccaaggagtctccagaccaaggctcacatggggatgaatgaaggcctctacttcctttttcataaaggg aggcttcatttgcatatgttcacccagtttgtagcatcatccacagtttccaataggcatgcatgatctcatgtgggcag acagtgtgtttctgtggttgactagaggaagccagggagacatttgctactgagcatggctagtatctgtgtgtgtgaga gtgagtgtgtgtgtgtgtgtgtgagagaaagagagagagtgtgtgtgtatgaatttcgtttcaaaatccatatgacacct acagatgttatcatgttgtctattgagataaagaattttggagttcttttaatcacaaatatggaaaatgttataaaacc ttcccaaaggcaaatctgaacactaagatgtgttgtgatgccaaagactctgctttgaaggagaaaaggaaacaccttca cctaccatcagtgttctgcaagacagtgacatctttcacaaatgcaacgtctccagcattctcagccaggcacctaaaat gttccagaaaatatacacataattacagaagagaaactagtggggctttcataaatatttgtaatatgcattccaaaaac tgaaatatggaagtaaacatctaaaagacaactatttctaggaatttactgtttacagcggcagattgaacacaggtgta cctgccctccttttaaaaccctatataaaagacattacaaaaccaagaaatctaaagatatgcgacccaggaaacaggca atctaacatgaagtaagacaaaggaaagcaccaaaataatggtcaacaggacccccaggaccacagatgtgcaggcggcc tacacagcaaccagtccaaactgcagcaggaagatggatgccttctggagcagcacttccaagtaaatgatgaaactgtg atagcacccagagagagagagagagagagagagagagagagtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgt gtgtgtgtgtatgcatgttgttaggagatttacattactggcagacagtttggggatgagatagtgatgtgtttttttaa gtgcagaaaattaagcaaataagaaaagacatttatgaactccagagtaaacaaaaagtttgtacaataagggaaatata atatgagaataacgcttacacagtcataagtactgaatatgacattagcgtgttgggtgctgaagagagttgaagtctgt ggttgtgtggtggaaaaggtgctgggggcagtgtgagaggctagatcttcttctatactacagagtcagcagaaagttaa aaattaagaaccagcattataaggatgatagaaataaaggggtatgacactggtttcagcttttaatgattttgctataa atttccccaatctagattctagatataatttaaacaaaagacaagggattttcttccagtataattaggaatattaaaat gtgggtgtttccagtgaactaataccttgctgcaggtctgaaaaaaaaaaaaagaggagcacatgcttctttcgggctct tatgagacatgtgttcagcatttctgagtagaatcacatttccatttgcaaatccttagtcccttaaagatatttttata cattcacaaaacatttttttttgttttgggtctttttttatgagccacttatatagcaaaagctacttttctgtcattcc attactggaacaaggctgttgaatttatattaaaaagttcagacaccctcagacacatgacgccatctggtcgtgaaatg tactcttggcaaatggaggaaaaggaacaggggaagatcctctctgcacccttcacactggtaaatagtgcccctgagaa gcaacacccggatgaatggtgctgtaaaacgtggggtgtggttacaagtcactaagtggttataacttatgaattctgaa aacttgttttttggcttatttttcacttcgttactggagaataacactgcaattctgccatctctttgccatttctaagg ccaaagtcagagaaaaagggaaacctaagccatagtcatgacctaggtgagaagaaaaggggcggcgatgggaaagagaa ttcttccccataaatggaattgtaggaagcacttaggataccacactctacccatttgattttcaggacgaggctattga ggcctactgctgttgatcttggctcaaagccacagggagaagcactgcggagctgaggtcagacagccctggtgccagcc tccactctctggggcggtgggtgtggtggggacagccctcactggggccacccatgagctgacccacaggatgaccccca ctctgctgtgacaggtcacatctggctccttagaactgcaatgctgacatgctgagggatgaggtaagtccccatcctga tggagctcagtcacagactcaccggaaagccccagtgtagccgtagtatctctcgttgctgttgggcacgcacttattct caccctgctcgtcgccaatacacagagcacagagattagatctcgggtcagacccaggggcacagctttgactgaaatat tcatctggagagaaggaacacggggagtcagctcttcaaacctgagtccacacaagcaacctttacctaacagccgatgc agggtggtttcagttcattagacttcccaggacagcaatctagatagaacacactcaccatcacaaagcaacatgttgtc accaacataggacccaccagaaaagcttcattcagactgtaggcacagatggacacccaactaaggctggggatgagagc tgtggctgcctggagggtcccgtcatcacagccttgagctggggactcagctcatgaccgtgatggctgtgtgcagcaga gcctgtgagttgcctagtccaggatctgattttgtttttatcagtaatggaaaccctgctttgtatctgggtgcttggcc ctttggtataaagactagacttatcagactccctggggctcatatggccatatgggtagctataggccagtgaaatatca gcaggagtgttgggcgccagcttctcagaaacatccttgaaagacaattggtacatgccttttgccctttcttctccttc tctttct catcctgcacatagaatgcagaagcagggactggacttagagatgcaatgtgggccatgaggtgaccttgag catgaaagccacacaaatggcagagtagccaaatgattaaagcccaggttccagaccccatattgtcttcataccagccc taggcaaaccacctctggactacatgacacagaaattaacttctgtcttgtttaagcctctactatttcaggagttttct gttccttgcagctgaacctgatctgaattcgttcattgtgtgatttaacccaagaaagaataaacaaaggtgacaagaaa gctctgccccactgagcaaacgtcacccattatcagactcccactgctgctggaagagccacactatgtgtcaacctcag gaaaagctgggagttcccattccatcctggcagtttccctacagctcagaggctgccatggagctggtgaggagcagagc cacgtgaaagctgcctgccccggccaggatcaaaaacccatgcagtggagcccctgccctaggagacgcccatacaagaa gggagtcacattgaggatgtgctacacaccatgccacggggcccacagcaggcagggtgtggctgatgctgactaggatg agtgtggggtgtggtggggagagaaaactgcagaagcaggtggagccaggctcttgaggtcttattcaggctccgttgca gtgtagagtaagcgtcagttttgcttagtaacaggagtcacctttcatgaggcaggcagacatctttccccaagctggga agccagagtttaagaggaatttaggtctggagctccaagaggtaaaaagcatttgcacatcttggaacttgcatttattc ttagggtgcagcgaaataggcagatattccaatctttaatcttggggtggggtgaatggggcatgggaagtgctgtgcag ggaaacccccagtgcacccacgcctccagggggcagccacagggagaatttccttatgctggaagaggcctgcaggccac tatcagcctgcaaatcccctcccctcccttccctaaggttccacagcacaatatgcctaccctccagggtggcccaccca ccgcacctttggaactccttaccaaatttgcaggagcccgtctggttgaagagcaggcccatggggatattccagcctgc agtcctgtccacggcggtgtggcaggacttcttgcctttcacagagttccaggtaaggctagtgtctgatctcctaacca ccgccacagcaagatatcctggcataacagatgacagaaaaacaagtcttaacctccaggaggcctggcacatggattcc agtggagctgtctacagcccaggccaaaacaggccaagaagcaacaccaggcaatgattccctcaaagaactggcctttt taggtagaccgagaaagcataagctgctgccttatgttaaggtgagattgatgaaataaaacagtaagaaaagctgatta ttttagtgattacaggggactgtcttcaaccagccacacaatgtccctgagttacaaaccagcaatgcatctctcagtgt aagcttctacagcaacaaacactataaacaacaagagagaccccaacagtgcataaatcaccaaccacagtgtgcatcag gcaagagcaccaacatccagccagctaacggctgtgtgggtacaggggcacatgtccccagggactgccctgagctgagt ctgaacccaccctgcactggttgaactcaacatggttgccgttgtcctcctgagagaatgcatctgacagacacccacca agggcaagtcttttctgaaactgagcaagcaccagctctggtgggcaggaggagtggtgcacagagcactgggacacgag tcccaggtcacgaggacccggggtcaagaccaggatctaccacagtattacctatggctgtgagtgagatcctgggcact tggggactctcggtgccactgtttcctcatccccatgaggtggggaagtagcaccccccattccatgaccatgacaaaat gagggactatatggatgttctttgccaagtgtgaaggtcaatataaacattaattagaactattcctctgtgaattattt gcacccttaaaattattgctcctagaagccctatagcttctagggctgcaattctttctgttttttttacagttcctgcc acttcctcttccagcaacaagaacttatccttgaccctgaaagtggctaatgccaactcaccttccacaggtctatccac acagttaggatcagggtcactgctttgttgggattctgaaagaataaagacaagccagacatcattatccattcagatgt agtgagaagccacaaactcttaaatctcaatgatgcagaatcaaatccaaagagaccgtcccagcagttccatgcaggag aaatgcgtctatatgttcaacaaaagacatggcacagagattcacagctgcattattcaccacagccaccaactggaaac tactcaaatgcccatccacactcaaatgatgaataatcacagtagactcacacagcgacgagactgaacagtctacaact acacacttaggtggatgaaaagcataacgatgagcaagagaaaccagacataaaaaaacacatgctgtgtaattccttta acatgaagtttaaaacataggcaaacttagatctgcgaccttagaagccaggagagaggcttcccttgcaggagtaaggg ggcgggggacaggaggacataaggggcttctgaaacttgcagtgtttgttctgggcccgagagcatggactgtacagtgt gtgaagtgccatgagttgtacatttatgtgcacttttctgtttgtatgttataattcactgagatcttctggaaaattaa gaagataaaaccaacctgtcccttgttaattctcaacacaataggctttgtgggtaacacggcccctttcatttcttctt tccctgattctcccttttgaatgtatctgttca cataatgtttcacctgcattcaccgaatgggattactcatagcccc actcccatgacccagagggaatataccagaggatgctaactccacttactgtagttctctgccaggacaggcaccaaacc acatttgcctgcagtgtacacatatcctccatccaaactcatggcatcagcttctcctttctgcaaagacagagcagatc tccagcaccacagtgaggctgcatcccgtcctgcctgtctatatagctctctgagagaatggttttctgtcaggtgacca gtgaaacagcagaaagagatggactattcaaactgagcagccagaggaaacaccgtgtgcaccactaattctctcccagc cctgcctactttctgggctgtcaattcaactggaaagaccaggcacaggttgcactaatcctctgtcctctgagcaaaac cttttctgtgtccctggcactttggggacaccttcctggagcagtctcactgactgaggacacagatgggaacagctggc ctcatctaatctgaactcattagcactccactccaagcgctacacagaagttgtccaacacataagctgaagtcgtcata ttggcccaccaccagaatgaacaagtccaggctacaacacaggatcatggactcatcagtagtatgaaacttcctctttg acccagtaatatttttacaactatattaaaaatagagaagtggacaaagatttctactcaagaatgctcaccacagggtt attgataatagcaaagtaagggacaaagaggaatgggggcatgactaaactgagccatattcacataaaagatatcctgg aagcatgtttaaaaaatgttttcgtccgagtgctgtggctcacacccgtaatcccagcactttgggaggccgaagcagga agattgcttgagcccaggagttcgagacgagcctgggcaacaaagcgagaccctgtcgctacaataataataataataat tatgcaggtgtggtggcgtatgcctgtagccccagctacttgggaagctgagatgggaggatcacttgagcccaagagtt ccaggctgcagtgagatgtggtcgcaccactgcactccagcctgggtgacagatcaagaatctgtctcttaaaaaaaaaa aaattaatgctttccaagagtaaatattcatgtggaagaatgcccattatacgctgtttagtgaaaagggcttaaaaacg acatactgcaacacttcattattgttgcatgcatatctgcagatgtgcagagaaatactggaatggagaattagccagac tttaaccatgtctgtccctctgtgtgagatcacaggtggtttggggggtttgttgttgttttgttttaacataatacctt tccatattttccaaattccttataataatcctgagttgttcttataaccagaggagtgggaaacccacagtaaactgctt tttgaaactaaaatgctttctggccctgagcacacctctccaggcatccctgcctcacccaggcccccgtggcctctttg actgttgacttcactttaagcagatgcccaggccctaggtcttccaccgggcccaccgcccgcccctgtgatggagctcc ctaccagcaccagggcgatgcagtcctctgtggtggaggccgaggagcaggtcacgctgccttcgctcaagccactccac tggttacacttgcgcagctcctgctcgcccaccgcacaccacacgacccgcgcacgccgggcagccacttcctcctcacc tgccagagggaagaccgcaggtggctgggcaacctgagctttgccaggttgtccaacctccccagagccagggtcctgcc cagactctccctggaacaggagctacagtacatgtgtggacatgtggacccataccctctcctcctccacttctcagctc caagccccttcttcaggtccacagagctccctgtgtttcccacttctgttcctttggagaagttccctggcttctaatct atccattaatctttagagtcaggaggcgcctattgtctctgtctctgaggataaacgctccatgacccagagaccagtga cagtcccaagagatggcctaggggaccttgagcccaaccctgacttcccctaacgcctgcaatcaccaccaataactacg gtgcagcctctgggttcccccagactcccacccccagccccccagtagagaaggagccatagctgagttcccccaccatg gtgtccccaactaagttcaaggtctgggcctgggaagtgtgggtaaatccaggcccccggattcatccaggaggggtcct ggctatctttgttcatgttcatgtttctcacttaataggaggcaaactgatttttctgccaggcctggggagcctgacgt gcactgatcaggtggccagactattcttttagagacacctgacctaatccacagaagacactcacacctgcatcaaacct ccacgatgaccccacagtgtctgggaaaaggagtgaccgccacaaagtagggccacctgctgggaagtagaagaccacac caggcggacctcaggaccctcctgggctcactcacttttcctcaagttctggatggcagtgaagtagccggagccaaggt acagcccagaatctatcctcgggggcaccctcgaaaacccaatggcagagtccttgaacagcagatctttctgcccacta ggggagccaaagagctggaatttcggtgacttgtcctttccaaacttttcctaattaagaaaaaatagaattatggtgtc aatggtaaatagggaggaaacaaaaaaatgatgttaaaaaagagtatctggagctttgggatcattctaactgagagcag gagcctcggttgagaccctcctgcagagggacttgtgccatctcggagacccaagctcagctatggctcattctttgaag agttgctgaggtccaagcaccttagggccctgagaagattgcatcgaccaccccctgcttctgctcccatcataagacgc tgtcagcccgtgtgacagaagagtttcattgcttctgctgtccacagtacagcctgggcaagcagcccaatgcattagtg tgctatcctgcagcaaagctacaggacttctggagtggcagaagtcagggaagtaagaaaccttgctccctgccccccat atccaagcaagtggggaggaccgtgggtgaagatacctgtgcctggcggagaagattccagatggcatcctccttgccat tcacacttcgtgccacaacggcatgagaagggacccgggccagatggcagtctttgaacttgtccactggcttccgagtg ttgtctgggcagagtaactcatactcgtccctttcagcctcgtctgacaggtcctctgcagggaaggtgaggtgggaggg agtctagataagccgactccagcagtaacctcgagctatagttccccttctccctatagaattttgagcttggggagata gctgacaaaactgagggtcagaaaggcaggggtttgctccagaacactcagaaaggtaaaggtagtgccccaaaagcctc agggggcagccgaggtgtgatcctcatcctaaatcacttaggccaccctggggttcccgtgcagctgctgcctggcaggc cagagaggccaaaccagacccgtctgtttctgcggcatctctgcctggaaaagtcactttgcagagacaagctcaggggg ccaccaagggttgctcccttactcacatctctgggaagaataaaaatgacaaaaatgttaacaaggcagggaataaggca ggaaggtgagacactttccaacactgagtatatcaaaagaaggggaagaatggttttatgaatgagttcaggcaaatgtg gaatatcatatataagttgcttcagaatgtgtaaagtgaaaaaaatcttgcccgagtcattttatgagattagtacaacc ttgatgtcaaaatcagaaaaagtataggagggaagaattaaaagtttattttacttacgaacataaatgcaaaatttgta aataacgtactaactaactcaatctcacagagtatttaaaaagctaatagattggaatgaaggtttaccagtgtattcca ttaacaaaagaatggctgaacatcaaaaaaactaaagtaatctgcatttaatggcagaaaaccatgagatcgtcttcatc ttaatagatgcagaacgattgtttatgtgttcaacatctatttgtgtgtggtttttttttcagcctcagaaaaatagtaa tagatagaatcggtaaagtttttttgtttgttttgagacggagtctcactctgttgcccagcctggaatgcagtggtgcg atctcagctcactgcatcctccatctcctggagtcaagagattctcttgcctcagcctcccaagtagctgggaccacaag cgcacgccaccaggcccagctaatttttgtatttttaatagagatggggtttcaccatgttggccaggctggtctcgaac tcctgacctcatgtgatccacccgcctcagtctcccaaagtgctgggattacaggggtgagacaccacgcctggccataa gttattggcttgataaatgccattaatctacagcaaaaaccttactaaaagaagaaaatgtagacattcaccgcaaaatc aggaacaaggcaaggatgcccactgttacaatgccagcacaattctagatatccagatcacacaatttacaaaagaaatg tgagatataaacactggaaggaaaaagacacactcttatttaaaaagatgatatcgtcatctacaaaaaaccaatgaaac caacagaaactaataaaactactcagaggagtaacaagttataagagcaacctacaaaaatcagatgttatcctcattaa caataaccaaatagaaaccaatatggactataagatgttacaatagcaactaaaaccattaagtagctaataattagcct cccacaaagacacatcagacccacaaaggaaaaattttagttctatcaaagaaactaaaaagaggtgtgatcaaatgggg gagatttagcatcaccatggactggacaacttaatgttataaatatgctgatttttcatggaacaatttaaattcagtac aattcgaatcaaaattaaagtatgattttttccagaaattcaacaaaataattctgaagttttagctgagtatatttgaa aaggaataataaagtgagaggggagagggagctctctc cattctctctctcttcctctcactggctctctctctttctc tccaccagatagtaagacccattggtaagccacagtaacaaaagcagaaaaaatgcaaatacaccaatgaaataaaatag ctcagaaactggtccacttggatatatacaaacttggtgtagaattggcttcacatatggcagaaaaaatatactttttt tattgtaaggtaaattgcctcactgtaaaggggataaaatgctaaagccaaatctatatctgactttctaggtagagcac atataaatagatgaggaaggggatcttcaaatcttattttaggaaataattatgatttgggtgtgaagaagggcatcttt gaaatatctcaaaactacaaaccaacaaggtgaggcttgtggatttgaccttatcaatatcaaggatttttgatcaacag agactaccgttgtcagatttttgactgagaagaggttttactaaagtttaaaatcagcaatagtttgatacctagataga aggaacttctgtccttgaatcaaaatcatgcagaaacaaggtgtgaaactcaatttaaaaagtagtcaaatgtcacaaaa taagaaagggaagcccaaacggctagcaaatatgttgaaatgatcaaactcaccagctgtcagagaaatgaaaattaaaa ataaaacgaactatctattgcattacaaccatcattcggacaaaaagtatgaaagtcaaaaatacttctaactgaagttg tggggaaattagaacacttgcagagtgtcattccagacagcagcttggtgatcctgggtgcatgtggggtctgtctctgg tggccctgggtgcatgtggaggtctgtttctggtggcctctgatgaatgcggggtctgtctctgatggtcctaggtgaat gtgggtgttgtctctttctctggtggtcctgggtggatgtggggtgtgtctctgatggtcctgagtgaatgtgggtgtct gtcactttctctagtggccctgggtggaatatagtagccctgtctctattggtcttgcatgaaatgtagtgagcttatgt ccactagtcctgggtgcagtgtgtttagcctctacatactcatcaactgctttattataagtccaggagggacgctgtcc agcaggtaagtaaggaacacaggtgaaggtatcagtcgtgtggctgcatgtggtagaggaaaagagagcacaacctctgt ccatcactatggtgacagagaagtaaaaggtggatgtattccacggaacactcctcaactgttaggacccctgagctaga catgtatacaacaataccgataaacctctaaaacaaaatgctgagcagaaaacccaagtagcaggatttctaatgctcac taaaacctctatgaacccagaaaccggaaacacaaaccagcacaatctgttctgcatgagcacatgtgtcttggaggact ggaggacgcattgccaagcacctaggcatgggtgtctatgaggggaagagaaaggcagtaggcacaggaggtttgaagaa aactgatcatttaaaatatgaaagatcataaaatcagagctgtgccctgtaggaatcttgaaaatggtctgccatgaact taggaatctaattagctcaaaggtcagagtcatgatcaagtaagataaaaggggtcagtacccacggctcattaccctgc tcttaccaaacactgtgctctctctgataaaagccacgtctccagccccgtctctcagacacctgtgaaaagagaaacca tcaggggtaagcacaggcagccctccccagcccctccctgtggaacagtagccctggcactcagcatctatgggtttcta ctccctgcagggcagggctctgaagctt (SEQ ID NO: 12208) tctagagccaaggtcacggaagcccagagggcatcttgtggctcgggagtagctctctgctgtcttctcagctctgctga caatacttgagattttcagatgtcaccaaccaccaagagagcttgatatgactgtatatagtatagtcataaagaacctg aacttgaccatatacttatgtcatgtggaaaatttctcatagcttcagatagattatatctggagtgaagaatcctgcca cctatgtatctggcatagtgtgagtcctcataaatgcttactggtttgaagggcaacaaaatagtgaacagagtgaaaat ccccactaagatcctgggtccagaaaaagatgggaaacctgtttagctcacccgtgagcccatagttaaaactctttaga caacaggttttttccgtttacagagaacaataatattgggtggtgagcatctgtgtgggggttggggtgggataggggat acggggagagtggagaaaaagggggcacagggttaatgtgaagtccaggatccccctctacatttaaagttggtttaagt tggctttaattaatagcaactcttaagataatcagaattttcttaaccttttagccttactgttgaaaagccctgtgatc ttgtacaaatcatttgcttcttggatagtaatttcttttactaaaatgtgggcttttgactagatgaatgtaaatgttct tctagctctgatatcctttattctttatattttctaacagattctgtgtagtgggatgagcagagaacaaaaacaaaata atccagtgagaaaagcccgtaaataaactttcagaccagagatctattctctagcttattttaagctcaacttaaaagga agaactgttctctgattcttttcgccttcaatacacttaatgattt^'aactccaccctccttcaaaagaaacagcatttcc tacttttatactgtctatatgattgatttgcacagctcatctggccagaagagctgagacatccgttcccctacaagaaa ctctccccggtaagtaacctctcagctgcttggcctgttagttagcttctgagatgagtaaaagactttacaggaaaccc atagaagacatttggcaaacaccaagtgctcatacaattatcttaaaatataatctttaagataaggaaagggtcacagt ttggaatgagtttcagacggttataacatcaaagatacaaaacatgattgtgagtgaaagactttaaagggagcaatagt attttaataactaacaatccttacctctcaaaagaaagatttgcagagagatgagtcttagctgaaatcttgaaatctta tcttctgctaaggagaactaaaccctctccagtgagatgccttctgaatatgtgcccacaagaagttgtgtctaagtctg gttctcttttttctttttcctccagacaagagggaagcctaaaaatggtcaaaattaatattaaattacaaacgccaaat aaaattttcctctaatatatcagtttcatggcacagttagtatataattctttatggttcaaaattaaaaatgagctttt ctaggggcttctctcagctgcctagtctaaggtgcagggagtttgagactcacagggtttaataagagaaaattctcagc tagagcagctgaacttaaatagactaggcaagacagctggttataagactaaactacccagaatgcatgacattcatctg tggtggcagacgaaacattttttattatattatttcttgggtatgtatgacaactcttaattgtggcaactcaaactaca aacacaaacttcacagaaaatgtgaggattttacaattggctgttgtcatctatgaccttccctgggacttgggcacccg gccatttcactctgactacatcatgtcaccaaacatctgatggtcttgccttttaattctctttttgaggactgagaggg agggtagcatggtagttaagagtgcaggcttcccgcattcaaaatcggttgcttactagctgtgtggctttgagcaagtt actcaccctctctgtgcttcaaggtccttgtctgcaaaatgtgaaaaatatttcctgcctcataaggttgccctaaggat taaatgaatgaatgggtatgatgcttagaacagtgattggcatccagtatgtgccctcgaggcctcttaattattactgg cttgctcatagtgcatgttctttgtgggctaactctagcgtcaataaaaatgttaagactgagttgcagctgggcatggt ggctcatgcctgtaatcccagcattctaggaggctgaggcaggaggatcgcttgagcccaggagttcgagaccagcctgg gcaacatagtgtgatcttgtatctataaaaataaacaaaattagcttggtgtggtggcgcctgtagtccccagccacttg gaggggtgaggtgagaggattgcttgagcccgggatgatccaggctgcagtgagccatgatcgtgccactgcactccagc ctgggcgacagagtgagaccctgtctcacaacaacaacagcaacaaaaaggctgagctgcaccatgcttgacccagtttc ttaaaattgttgtcaaagcttcattcactccatggtgctatagagcacaagattttatttggtgagatggt^'gctttcatg aattcccccaacagagccaagctctccatctagtggacagggaagctagcagcaaaccttcccttcactacaaaacttca ttgcttggccaaaaagagagttaattcaatgtagacatctatgtaggcaattaaaaacctattgatgtataaaacagttt gcattcatggagggcaactaaatacattctaggactttataaaagatcactttttatttatgcacagggtggaacaagat gagaagagctgagacatccgttcccctacaagaaactctccccgggtggaacaagatggattatcaagtgtcaagtccaa tctatgacatcaattattatacatcggagccctgccaaaaaatcaatgtgaagcaaatcgcagcccgcctcctgcctccg ctctactcactggtgttcatctttggttttgtgggcaacatgctggtcatcctcatcctgataaactgcaaaaggctgaa gagcatgactgacatctacctgctcaacctggccatctctgacctgtttttccttcttactgtccccttctgggctcact atgctgccgcccagtgggactttggaaatacaatgtgtcaactcttgacagggctctattttataggcttcttctctgga atcttcttcatcatcctcctgacaatcgataggtacctggctgtcgtccatgctgtgtttgctttaaaagccaggacggt cacctttggggtggtgacaagtgtgatcacttgggtggtggctgtgtttgcgtctctcccaggaatcatctttaccagat ctcaaaaagaaggtcttcattacacctgcagctctcattttccatacagtcagtatcaattctggaagaatttccagaca ttaaagatagtcatcttggggctggtcctgccgctgcttgtcatggtcatctgctactcgggaatcctaaaaactctgct tcggtgtcgaaatgagaagaagaggcacagggctgtgaggcttatcttcaccatcatgattgtttattttctcttctggg ctccctacaacattgtccttctcctgaacaccttccaggaattctttggcctgaataattgcagtagctctaacaggttg gaccaagctatgcaggtgacagagactcttgggatgacgcactgctgcatcaaccccatcatctatgcctttgtcgggga gaagttcagaaactacctcttagtcttcttccaaaagcacattgccaaacgcttctgcaaatgctgttctattttccagc aagaggctcccgagcgagcaagctcagtttacacccgatccactggggagcaggaaatatctgtgggcttgtgacacgga ctcaagtgggctggtgacccagtcagagttgtgcacatggcttagttttcatacacagcctgggctgggggtggggtggg agaggtcttttttaaaaggaagttactgttatagagggtctaagattcatccatttatttggcatctgtttaaagtagat tagatcttttaagcccatcaattatagaaagccaaatcaaaatatgttgatgaaaaatagcaacctttttatctcccctt cacatgcatcaagttattgacaaactctcccttcactccgaaagttccttatgtatatttaaaagaaagcctcagagaat tgctgattcttgagtttagtgatctgaacagaaataccaaaattatttcagaaatgtacaactttttacctagtacaagg caacatataggttgtaaatgtgtttaaaacaggtctttgtcttgctatggggagaaaagacatgaatatgattagtaaag aaatgacacttttcatgtgtgatttcccctccaaggtatggttaataagtttcactgacttagaaccaggcgagagactt gtggcctgggagagctggggaagcttcttaaatgagaaggaatttgagttggatcatctattgctggcaaagacagaagc ctcactgcaagcactgcatgggcaagcttggctgtagaaggagacagagctggttgggaagacatggggaggaaggacaa ggctagatcatgaagaaccttgacggcattgctccgtctaagtcatgagctgagcagggagatcctggttggtgttgcag aaggtttactctgtggccaaaggagggtcaggaaggatgagcatttagggcaaggagaccaccaacagccctcaggtcag ggtgaggatggcctctgctaagctcaaggcgtgaggatgggaaggagggaggtattcgtaaggatgggaaggagggaggt attcgtgcagcatatgaggatgcagagtcagcagaactggggtggatttggtttggaagtgagggtcagagaggagtcag agagaatccctagtcttcaagcagattggagaaacccttgaaaagacatcaagcacagaaggaggaggaggaggtttagg tcaagaagaagatggattggtgtaaaaggatgggtctggtttgcagagcttgaacacagtctcacccagactccaggctg tctttcactgaatgcttctgacttcatagatttccttcccatcccagctgaaatactgaggggtctccaggaggagacta gatttatgaatacacgaggtatgaggtctaggaacatacttcagctcacacatgagatctaggtgaggattgattaccta gtagtcatttcatgggttgttgggaggattctatgaggcaaccacaggcagcatttagcacatactacacattcaataag catcaaactcttagttactcattcagggatagcactgagcaaagcattgagcaaaggggtcccatataggtgagggaagc ctgaaaaactaagatgctgcctgcccagtgcacacaagtgtaggtatcattttctgcatttaaccgtcaataggcaaagg ggggaagggacatattcatttggaaataagctgccttgagccttaaaacccacaaaagtacaatttaccagcctccgtat ttcagactgaatgggggtggggggggcgccttaggtacttattccagatgccttctccagacaaaccagaagcaacagaa aaaatcgtctctccctccctttgaaatgaatataccccttagtgtttgggtatattcatttcaaagggagagagagaggt ttttttctgttctttctcatatgattgtgcacatacttgagactgttttgaatttgggggatggctaaaaccatcatagt acaggtaaggtgagggaatagtaagtggtgagaactactcagggaatgaaggtgtcagaataataagaggtgctactgac tttctcagcctctgaatatgaacggtgagcattgtggctgtcagcaggaagcaacgaagggaaatgtctttccttttgct cttaagttgtggagagtgcaacagtagcataggaccctaccctctgggccaagtcaaagacattctgacatcttagtatt tgcatattcttatgtatgtgaaagttacaaattgcttgaaagaaaatatgcatctaataaaaaacaccttctaaaataaa aaaaaaaaaaaaaaaaaaaaaaaaaagcttcagtatgcaaattttcaatgacatgtgcctgtggattctgaaaattcaca gatctgtctatccttagctgagactgaaggcatctacttcccaatgaccaaatcctggtgctgtggcgacactgagcagg aactccattagaatatcaatatcactctgcagacattccatgatgtaagctatgttttctcttgttgcaattacacttaa tttaccaccagctgcttcaatgtcatgggctatcttgaaaaatgaagctcctttcgtagtcaaactggatgcaagacaca gcaaatgagaagttactaaattgttggagtcctcatagctactgcctgctttaatgaacaaaccaattcttgatgcaggg catagttttccaaaggagaaatcataaaaccatttggaaatttgatgatctcaaggtcctgatgatgtggagccactcct atgggggtagctgtggctttaactttgggggcaactttgagggaataaagtctcaaaaagagggaataaagtctcaagat tgttcgtgacccatagtaacttctggcttaaaggaccattcggcaagtttttaaatgtattttctataatttccatgtag ttctttatattttctatttcttatttaaaacctctattttagctcgtttcctttgacactgctctggcagggaaaggggt ggcactgcctcattactgccaggtaggggtagaagtccattatccacttggtctccattgatacccaaagtggggagagg ctcctgttactgctggtgagggtgggagtccccccactaagtttctgctaatactgtcctggtggcttgctactattccc atgaagcctccactgatactacattacttttgggtggtggcaaatgtcctgcctctccactagccctcctgctctaaaac aacccgagtagggagtgggaaggaagctttgttactggtaggtgggagctgaagtccagacttgccacattgtcccactg atgctacagggaggaggaagcgggccacattactgcctgatagggatgaaagccccagctccctacctggccttcgctga taccagcctgctacaggagtgaagagagatttgaaggcctcaatatagcctgtcgagggtggaagtcttgctcccaatgg gcctttagcagcatgggtgggtgtggggccatagctgtctctgtactgcttggctagagtggagtatttgaggtccaaaa gttttctgtctttctagccctttggttagaaagagcagacttttgttggaagtatttttttgtgtttacctgttgtattt ccaggttcctagcttctccagcacagtctgggatgtgtgagacacagagaaaatccagtgatgttactaccgtatggttt cttgggtcccaacgtctctagctaatctgctccaccttttggagttttcttatttgttttagatcagggatttagtcata tttaataggagaaatatggaaaaatacttctactctatcttcctggaagttcctgtttattttttatgtccttttcctct ggctagaccgtaagagacttacgaaacaaacacttacacattctactaaactcaatgtccaaagtttgtgaacttcttga atattgcttgttcatttccacccccagtcactgactgaatctccctgctgtctgtctacaatgccaatgagcttctggtt aacttcttctcatgcatgcttaggcaacaacttcccagttttactacacttgcccatccctagttttgttgttgcttaat cccttggcctagtgccaccatactcctccagcagagcaaccaattcttacattataggacagcacatatccactaaaaac agttcatgccacaccaaccacatttccctttgtcaacaaaattacttgatagataattccaggaatgcctgatgaagctg attgacaacaagatatttggcagactctctgctgcctatacataccttagcatgtggaactcaagtaatgagaggtccat ttaattggattgaattgggctggataggattggattgaatcctgtgggatggctaggctaaattagaaatgaagactagt ttaacagcagtatccaaggatagttgactaatgagttaattttactctcaaagacagtctttagtagtaagctgtaatgc attatatcaaactattttccagtcaatgatttataagttacttgaataaggatgctaaagatgtgccttattgaaatggc aattagcacaaagttgggaatgaaatctaattagttaaataacagaatcacataaaaaaggacttgaataaatgtagcat cctaccatgttcctggatagaaagactgctatcgtaaagatattcattctcctcaggttaaattataaactcaatgcaat tcaacaggattttaaaaaactagacaaagtgattccaagtttacgtggaaaataaaatgtgagggaccaaacaatatttg aaaaagaaagagaataaaatctcatccttccagataccacaatgtattataaagcaatagtaattaacatgagggcagaa atgagcaagcaagtgaacaaaataagacagatagtcacaggaaactcatatatttataggtgctttgcgtataatgaaga tggtccttcaaatcagttgggaaaagatgggttattcaataaatggtgttgggtaaaattggttatacattggtgagaaa taaagtgaaactcctactttgtatcatatgcaaaaaatagattccagacagatgaaatatttaaatgtaaaaaataaaat tctaaaactactagaaaaaaaagaagaatatttttattcctttgaaatagaaaaggtcttactaagcaaaacacagaagt aataaatgaataaatgaagacaaatatgataaaaataagttaaaaatataagcaatctttctttgtttttttttcacctt tcctagaaaaaaatat taggcaacttgttaagcaaggtagattacaagaaaatatttacaacatttgacaggccacaga ttattatccagcctcatctgataagaaaacttcaacataaagatatctgttttttttcttataaggttcctcaaagtgag ccaatcacttcttaagctgaacaaaaaacaaaacagaagtgatcttttccaataatgaaaacaaacattgacagagcagc tgtaggatcctttcaggcaaattatgaaaaggtgccctttctcagaaaccacagttaccattcagctttgtgaccagagg tttgactgtaccctagtccctactagcaacccaaccacataaccaacttcaaaggtcctgaatgactgtgttgtacttaa tggcagatgatctatctcccatttttgtcctaaggattttccaagataatatatttctgcatttgttttgcttttacttc actccaaattgaaatctatttgtgggataagactaaagaaatgcttataggaaaattgatagcaccaaattcctatctta aaaaatgaaaaaggtttcaaatcaatgacctcagcttttactttaagaaaatagaaaaagcaggataagctaaagccaaa gtaaacagaagaaaggaaattataaagataagagcagaaatcaatgaatagaaaacaaaagaaaaaaatcaaaccaaaca gctgattctttaagcagatctataaaattgataaaactctagccagattgatcaagtaaaaaagagagaagacacaaatt accagtattaagaatgagagaggcaatatcactacagatcctacagatataaaaagtataagggcatactttgaataatt ttatgactataaattaggcaacttagataaaacaaatttcttgaaagacacaaacaaccaaagctcacctaaaatactca caaattgaatagtcttatagctattacaaaattgaggccaggcgcagtggctcaagcctttaatcccagcactttgggag ^' ggctaggaaggcggatcacgaggtcaggagtttgagaccagcctgactaacatggtgaaaccctgtctctactaaaagta caaaaattagccaggcttggtggtgcgtgcctgtaatcccatctactcaggagactgaggcaggagaattgcttgaacct 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aatttacaaaagagctttatgctcttgttaaatttgagggtagtcttctcaaaatctctgtgaggctagaaagtcagata ttgaaacacctgttttatgggttcaaagataggttcaaaagagagtaaatgattgttggggtggcaggtccagagagggc aggatcaaaactgcaattgagtcttctgccttataaaccagcatagcttccccaaggcacgtcacttctcgataaaatgg tgacaactagagtgtcctttcagatcattcttagaagcatggagtgctaggtcaattgtgtaattgatgaggaaataata atactaagaactcccatcttctacgtccttatatacaatcctgtcaggtagaagctgagtctcagagagaacaagttgcc ctcccaggaccaccaggtaagctcggcatagctgtgcttagaatgtaggctgtctggcttctgggcttgcctgcccaggg aggctttgtgggttctacttggtcatccagatcacagaggggcagcactgactcctacccagtgctcttgactgtacatc taatactttctactaagaaaaccccttctctttagaccaatggttttcaaatcttggtgtgcattggaatcacctggaaa gcttgttaaaacacagattgtcccaccccaagagtttctgattctgtaggctggggtggggacccatgaaagtgcatttc taataaggtcccaagtgatgctgatgccaccagtgtgtggacaaccctttgagtggtgaagctctggacaccctaatttg caaggctaatcaggcatatgtggcaaatgaatacgaactgaaattctgactccaatatcttcactgatattcctaatcca tagcatacacacagtcccattcgtttcccttttagcttttaatctacatttatcctttcttcctctgccactgccttctc tccagttagctcaaaccaggtaacacataaccgcctcctaactcatccgcccagttggtttctttggctttaatctagac ttcttatctccaccagatttgccttaccaaagcaccaatttcttaaggcagggttagaattaaaaatcttctgttcctcc tcattgcctaaaactcctaaacttatgattcaaggtcttccatgaccttcatggaccagtctaacgttttagcctgtcct aagtgacatgcctccaccacatacttcatgctttccactttctttctccatgtctttgttcatgcatttccatttcttct acctgcgatgtcctccttcgccatctctgtagatttaaaaatcctacagggctcatctcaaatgccctttccttcatgaa gcctttcatgaaatccccatcgagaggttttccctcctctcagctctccaaagcacagatgtctgcgtttgtggctatta tcttacgttgttttgtattaaaatttctccagctttacacatttgtcatcctcttaaggacaaacatcttattatggtca atgtgaagctatagaggataatttaatgaaatattccaagggctagtcattacacatgactgatttatctctgtaaactc atccacactcatccacctgattttgattggccaagttaatgaatcagagaggaaaagatggtaaaaatataataaaaatc tcctaggtagtctcacatcccacagagccccaggtaatgaaatgaggccctgagataatactttatgaacaataaaactc cgggttctattgacagtgaagcaagacctgagagagaaggctaaattcccttgtgtctagctgccacaatcttctgagaa taatggcctttcttcccgtctgccttctgaatcataggcaaatttttctctttggtgatccctaatacagaaaggggaag tcaaataaaatatatacaaggagaaggattctgggagacagagtttcttgattcccttctgcatgctcctcctcaaaagc ctttatgagcttaccttacatttaaattcttttaaacaaggcattatgtggtctggtcttttccagctccacacaccttc acactacattccccccagctaattctgctctgggaacactgaccttcttttagttctttgaacacattgatttctggtca agatgactcagtaacttcaacctttgttgtgcccttggtgctgtgaagatatagatatatattaaccactgcacaccaga aatcagaaatagcacaacagagaataaagtcattgagccatcttctgagctccaaaagacaaattttctccaaaaagaca aattcaggctctaaaacaataccttaaggaaccagaagtggaatagaaaattaaggtggtaagcagggctaaaccacatg cctgttgagcccaggtttggaagaagacaatggcaggtaggaatgtggtttctgatgggtaataggtactgttttcattt actttctgttgcttataacagaatatctgaaactgggtgctttataaagaaaaggaatttatgtcttgcagttagggaaa ctgagaagtcaaaagttgagggctgcaattgacaagtgccttcttgctggtggggatactctgaagagtcttgaggtggt atcgggcataccactctcagtgaggggactgagcatactaggtcaggtctttcttcctccttttataaagctatcagtcc cactcttatgataacccattaatccattaactgattagccaattaatccatgaatggattaattcattcatgagggcaga gccttcctgacccaaacacctcttaaagactccacctctcaatactgccacatgggggattaaatttcagcatgagtttt tgatgagacaaatattccaatgatagcagttattaaaagtacatgcttgagagaaggggattggagtcagcctcagtgct taaactcaaaagctaggatgaggctctaacactcctgaaagaaggagttgctgctggctccttaccagggctatatcttt tacagagcaggagacctaaagaggcaggaggacccggacatcgtttggaaaccaagcactaaaacaggccatctgttata cccccaatatcctctcaggacaagtgttttgaaccactcacacaaggactagtctgggcaagtgggctagatgaagaaac cacaaaatagctaagtggggagagaaagaccaaaaatactattttattcaaaatgaaaatacaatccaaaattccatgat tcatgaagaaatcaaatggtatgtgttaggtggttcttgcattgctatagagaaatacctgagattgggtaatttataaa gaaaagaagtttaattggctcataattctgcaggcttcacaggaagcatggtgctggcatctgctcagcttctggagagg ccccaagaagatttgctcaaggcagaaggttaagggagagctggcacatcacatggtgagaaaggaagctagagagagag tgcagggtgaggtgccacaagttaccacagccagatctcttgagaactcacttactttcatgaggacagcaccaagccat aaggtgtagggagccaaagtcccatgggacatgaccaactcagcattccactggaggctatatgatcaaacagcaaactg tttatcacgaatgcaggatgtgagcaaactcacaactggtcctgccaacagaaggtttgttggaggcaatcactccctgg tgcctgaggtaatctactgcaacatctagagaatgcagtcttgcaagcctactctggacagggcagctggcaccttattc catcccccttctcactatctttttttgcctaataaatacagagggctgtgtaaagctcagggcccttgtccactagaggc aagttgccccctgaccccttcttccaaatatactcttttgtctcttgtcttttattctcacatttgccccctttgttcag ttccactaggtccgtgcgggttatatactggtgccctgagcagcaacagaatcaggctctcaacaagtgtcatccgaaca tgggactttgaggacatgaacgaagaaggtctgctggagcagaggaacagaaattgacaaggtgaacagggaccctggga cgagtctgccagcagcggatataaggtcagttacctaaagaggtactgatcagtgccctaaagagatactgggagcagtg ctttaaagaagtactgggaatgggaaattttctgaatcagggtaacaaggggaagaatttgtctattaaagaaaaacatt atgtgcagttgcttaaagttgtattggaacagtctggagcttaggttaatttgcagacactaactatcacatgcgtccgt gtgaagagagtccaccaacaggctttgtgtgggcaataaagctttttaatcaccttggtgcaggtgggctgagtccaaaa aaggagtcagcaaagggagatagaggtggggcagttttataggatttgggtaggtagtggaaagttacagttaaaagtgg ttatctcttgtgggcagaggcaggggtcacaaggtgctgggtggggaaatcatgagactctttttctgggacaggagtgt cacaaggtcaattgatcagttggggtggggcaggaacaaatcgcaatggtggaatgtcatcacttaaggcaggaactgac tatttcacttcttttgtggttcttcagttgtttcgggccatctggatgtatagtgcagctcacaggggatatgatggctt aggttgggctcagagacctgacattcctatctttttatattaataagaaaaacaaaacaaaatagtggttaagtgttggg gcagcaaaaattttttggggtggtatgtagagataaggggcaatgtttctcagggctgcttcaagcacgatcacggtggt gtgggaatctagagtgggagagattaagctgaagaaaaattttggggaaaggggtgatattctggggttgttagaaggag catttgtcatatagaatgatgatggcctggatgtggttttgtatgaattgagaaactaaacggaagacacaaggtccaaa taagagaaggagaaaaacaggcattaaaggattaagaattgggaggacacaggacatccaattagagagtgcccaagggg gtccagtgtaattatttgcctggacaatgagttttggggctctattaggttgtcatataccaggccagattgatttaggt aaaaacaacactcttcatttaaaatatacagagtcctccttttttagcagtgagtaagttgagacctattcctgtcttct tatattaataagtaaaataaagcaaaatagaggtgaagtgttggtgtcatgaggggaacaggaagcagttcggtcctatt tgcaaattgattttgggggggtaaagaaaactagtgtacctttgcctgtccaattaataagtagacacatgtagatggag gagccacagaggaagaagagaactttgtaaggcaaaactggaaatgtaaagggaaaagatgagagggagcaccaaaagag gtgtcttgcacccagactcagggatotagtgagagcagcagctgttagaggttgtaatggggattaatggggctactggg tagagggggaggttcaacttttatggtgtatgagaaagcgcatagtgtctacaagcaacctttcattgctattcatagga ttgggtataagtaaacaagaagggggggctaggaggagagtctgaagaacaaggggaaggtagccaaggatggagtgaaa tgtagggcaaatgtcttaaaggaaatgagaggttctaagaggagggctagtggcttgtaacccacatggaagaggttacg aaaggatgatagaatggaatgagcctgtgaggctggaaggaggaattttccttggtccaagaaccatttgccttgtgtgg gaagagtttgataggtggaagtttcagtgggagggtaggcgggagtgactgatgagaaggagaaaaactggccataaggg acagaagttggaatgctagctgctcctttagctaccttatcagcataagctttgccctgagtgatgggatctgatgcctt ttgatggcgcttgcagtgaatgaccctagcttccttggaagtagagcagctttaagaagagtttttatgaagaaggcatt aataatggaggaccctcgtatagtgaggaaacctctttcaggccatataacagaatggaggtggagaatatggaaggcat atttagagtcagtataaatactgacacacaatccttttgcaagagtgagggctcgagttaaggcaatgagttcggcttgc tgagagggagtggagtggggcagagtggtagcctcaatgatagatgtgaaagatactatagcgtagcctgcctttgctgg tgagtggtgattaggcctagtggaactgccatcaataaaccaagtgtgatcagagtgaggaacaggaaagaaggaaatat gggaaaatggagtgaatgctaggtggatcagagagatacagtcatggggatcaggtgtggtatcaggaataatgtgggag gccagattgaagtccaggccaggaacaatggtaattgtgggagactcaacaaagagtgagttcaactgaaggagccgggg gagggggagagcggcagaaagtatatgcatcaggtgtgaggaagaaaatacattttgaaagttatgagaactgtagagag tgagttgatcatagtttgtgattttgagggcctttaaaagtattaaagcagtggcagctgccacacacagacatgagagc cagcctaaaacagtaaggtcaatctgtttagacagaaaggctgcagggcactgtccaagctcttgtgtaaggattctgac cgcacagccttgtactttggctgtgtgtaatgaaaagggttgggatgagttagggagagctagtgtgggagtagcttcta gggctgtttttaaggaacataaagaggagtggggaaaggatttaggatctatggggtcagctaggtttccttttgtgagt ttatgtaatggtttagtcaggatggcaaaaccaggtatccaaaggtgaaagtacccaaccatgtctaggaaggaaaggat ttgttgctttgtagaagggattggggtttgggagattagccggacacagatcaggagggagagcacttgtatttttatga agaattatgccgataggtaacggatgaggaagaaatttgggctttggagggggatacacgatattcccttgagaatagat gttggaggagcaggagggtgtcctgttgggaagattcataggaggggctataaagtagaaggccatcaaaatattgaata aggtgacaagcagatggacagaaaagtaaattatgagaaagggcttgactgaagtaatggaggctgtccctgaagccttg tggcagtacagcccaggtaagttgctgagactgatgggtgtcagggtcagtccaagtgtaagtgaagagaggctggggtg aagagtgcaaaggaatagtaaagaaagcatcttcaagatccagaacagaataatgggttgtggagggaggtattgaggat 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gtctcttctctattattgtacaccttgaaggtgaggttaattaagtcctgttgtggggtttgagggccataatctaattt ttgaagcttttttaatgttgggagtggattgggtaataaaatgcatattgagagtaagacagccttctggcccctctgaa cctagggcagtaaaatgtctaagagttgttgccaaagggaccatggactgggctgcgttttcatatttgatgaaaaaaaa agagcctaaatgctaactaatttgggagaggtcagataaagtaaaaggaacattaatcttgactatgccttcagctcttg ccacctctctaagaggaaattgttgggcaagtggaggagtgctagtcgtggaatgaaaccataagctggactgggtgtga ggaggggaggtgatagaaggattacagcgtaggggagtagaggctgaggaagaattgggacctggctcagcctggtgagg agtggcctggtgaggagcagcctggggaggaggagagaggttagatgggttcgtagaaaagaaggattcaaaggactcgg agcttggtgaggagactgaaggaacagacaggagagaaagaagaaagatttgggacaagtcgcattgggagcagagacta ggaagggagtgatgtgtaaagaatgcctggacatcaggcacctcagaccatttgcccattttatgacaaaaattatctaa gtcttgtagggtggagaaatcaaaagtgccattttctggccatttggaacaattatcgagtttgtattggggccaaatgg tgttgcagaagaaaataagatgcttaggttttaggtcaggtgagagttgaagaggttttaggttttttagaacacaggct aaggcagaagaaggaggaatggagggtggaaggctgcccataataaaaaggtaagtttagagaaaagagaggatagagac acagagagagggggtggtggtactca cagccaggggaggtggtacttgccaccaaggtgatggatcaaggcagtcatcc ccacggtgatcagacacctctgaaatgtgggtgaataatcaggcaggtgtccctgcagtgattagacaccaaggggagac tgtcttcccgagtccgtgaccggtgctggagttttgagttcacagataaaacacatctcctctgtctctaccagaaaggg aaaggaactgaaattaaggaagggagagattgaagggtggagagatagcaagagagttggaaaagagaataaaaagaggc cacttactcaatttaaaattggtgagatgttccttgggctgatctgaggacccaaggttgtaggtggatctcctcacgga atgagggtgaggacaggggactggtctccagaaggagttcccgagtcctggatcttcagcaccaaatgtcatgtgcatcc atgtgaagagagtccaccaacaggctttgtgttatcaataaagctttttaatcaccttggtgcaggtgggctgagtctga aaaaggagtcagcaaagagagataggggtgggtcagttttataagatttgggtaggtagtggaaagttacagttagaggt ggttatctcttgagggcagaggtgggggtcacaaggtgctgggtggggaaatcctgagacttatcatccagggaaggagt gtcacaaggtcgattgatcagttggggtggggcaggaacaaatcgcatggtggaatgtcatcagttaaggcaggaactca ctatttcacttcttttgtggttcttcagtttcttcaggccatctggatgtacacgtgaaggttacggggatatatgatgg cttagcttgggctcagaggcctgacactaacctcctgcagaagccacaaaaggttattacacataaaccatggtttccac aggcaggcactcttgatgtggaaaattgggatagagcaggattaaaacaagctcatcaaaaaggtcttaaagttgattct tcagttttctccacttggagtttagttcatactgtacttctgccattatctccttattattctgcggaacagcaggctga atctaaaaattggaaagaatttgttgtcctactcacagctccaattgaatataaaaaacaggagagggaggataaaaatt ggcctataccgcctcctccagatgcagaaacatctgtaccatctccttcagtggcagaaatagagatcccagtacaaaga attttatgctctgctgtcatagctggagagcccttaggaccttgtgcttttcctatttctgtaaggcctgatccaaataa tccacagcagtttattcatgaacactctccactagaatttaagttgttgaaggaattaaaaactagtgtggtcaataatg gagtacaaagccaatggttcctggaggaaggaatgctagacatagaactttgggagcaagtggggagaaatcttaaacaa caccaggcacaaaggcatcaggtcccagtaaaatcttttatgttaggggctttgagtagagcagccctggttgttacaca caaaagagcctaaaaagggaaaggaggaggaaatgtcacctgccttatcacctccccttccctcagtgccaatatcactg ggccaaaataacaaagaggaaatggaggtcttacctaagcttcctcctccaatagataggaagaaggacagaggatacgc tacagctatcagtccctgtcttaagcaggcagcattagaaggagagctcttagccgggtgcagtggctcatgcctataat cccagcactttgggaggccgaggcaggcagatcatgaggtcaggagatccagaccatcctagctaacatggtgaaacccc gtctccactaaaaatacaaaaaattagccaggcatgttggtgggcacctgtagccccagctacttgggaggctgaggcag gagaatggcatgaacccaggaggtggagcttggagctttcagtgacctgagattgcaccactgcactacagcctgggcaa cagagcaagactccatctaaaaaaagaagaagaaggagagctcttaacctgctcagtaatgcaaaatcggcaaggcaatc aggtgtatgtttataaaaagataagaaaaaggcattagaagccaaaaccacgtggccaagcaggcagtgggcaggagaaa atgctcagaggcagaaaagctcacagcgacaaagccaacaaggtctgcccaggacggcagcatccctctggcaaaggagc aagggagcagcacagacacaggcaaagcctaaacaagtacaatgtggccacctcccaggacctgcaccactgccctctgg ctctgtgggcagcccattgcaaaatttcatgtgttacatctcaggctatgattctctgctaagatgtaagtaaaatgtaa gaatttgaaaagcatcttttctaataatggccactattgtcatctctctcctatccctgatgtagctttccaaattcaat ttaagtaaaacagtaacctttgaagggaaagagattacagagggcccatgaattagttgaagagtaattaaaagctaggc atgtaaaaccacacattacgctttaaagaagaaatttaaacctaattaaatgatatttgttaaattagaaggtaaaaatg ttgtgccctgttgggaacaggcccccaaatctggccataaactggccccaaaacaggccataaacaaaatctctgcagca ccatgacatgtttgtgatggccatgatgcccaccttgaaggttgttggtttactggaatgagggcaaggaacacctggcc cacccagggcagaaaattccttaaaggcattcccaaaccactaatgatagcatgagcaatctgtgccttaaggacatgtt cctgctgcagacagctagccagagcccatccctttgttttggcccatccctttgtttcccataaggaatgctttcagtta atctatgatctatagaaacgatgcttatcactggcttgctgtcaataaatatgggagtaaaactctgttcagggctttca gctcagaaagccataagccccctgatttcccacttcccaccctttatttctgtgtgtgtgtcttgaattcctctagcgcc tctgggttatggtctccacaaccacgctggtcttggcagtgcccttctcagaaagtgaaaaagagttgtatgtaagtgta gtgaaaacataagcatgaatcactgtcttaacccactgattagatagtctttgatttgtacttgctaaaagagtcctaaa ttgagttcctcagctagtgagtcactgttttcaagactgtttgccagattgaagtccataaacttggtcagcccgaaaac tcaattacaagatctaagctattctgcctgtggctttaagcacatggttaaagtatattatttaagtctctccttctaga tatgctttcagattttctttttaaacttcttgttacttatttcagctttccatattgataattaatgcagtcaattgctc agttatgactgtgata catcaggattcctttaagtaaaaggcaattcaaagcggtattgcactcccccatacctaatgc tttaacactgtttactgatgggtctggtaaacatggaaaagctgcagtctagtagagaccacataattcaatcactcgat ctgagttcactagcactcagagagctaaggttactctgtttatttattaaagaatttttacaaccttaagctcactctgg actttccagccttatgtggcaaatgtagccatcaatttatggggtcaagacttacttacagcatgggatatgaggcttac aaatgagactttgataacccaggattttaaatgttgaagaacacgggatatcagagtgaaaaaggtttagggaaaattct gacaagggaaaattctaacctgatatcaataactggaaagacaggttaaaccctgcaaggggatacattgacattttttc ttcctcacttgctcttttctgctgtctgaatatgggcatgagggcaagagtcattttagaccaccaagtgaccttgagga tagaagccttatactagaggtggtgggaaagaaaaaacagaaggactcataaagaaaaaaataataaacctcagtattaa gatggaaaaattcccccaattggtctataggttgaacttcatctctattaaatttcagctatgtttttgcagaatttgat atgctgatcataaaatttatatgaaaatgcaagagacacagaatagtcaaaactttgaaaagaagaaagttggaggactt acacttgttgattttaaggctttttacaaagctataataatcaagacaatgtgttactgacataatgatagacatattga tcaatatagacaatggatgaatggagtagaattgacagtctagaaataaaaccttatatatatggtcaatttatttcttt atgtattctgtcatccagaatacataaagaacaccttcaactcaataacaacaataccaacaagggtgccaagaccaatc aatggaggaaataatagtcttttcaagaaattttgctgagacaactaagtatttatatgcaaaataatgagtttgaatgg ctaccatatacaaaaattaactcaaatggactatattaggtcagtgcaacagtaattgcagtttaccaccattacttgtt ttttttttttggtttttttttttgagacagagtcttgctctgtcacccagaccagagtgcagtggcatgatctcagctca ctgcaagctccacttcctgagttcacgccattctccttcctcagcctcctgagtagctgggactacaggcatctgggtaa tttttttgtatttttagtggagatggagtttcaccatgttagccaggatggtctcaatctcttgacctcgtgatctgccc acctcagcctcccaaagtgctgggattacaggcatgagccaccacgcctggcctaccattacttttaatggcaaaaatgc agttacttttgcaccaccctaatagaactaaatgtaagagctaaaactacaaaactgttagaagaaagcataggagcaaa tcttaatgacatgagagttggcaattgttttttagatatgacaccaaaagcatcaaggacaaaagaaaaaaatggataaa ttggacttcctccaaattaagagaacttttgtcctgcaagcaatactattaagaaagtgaaaagacaagtcacaaaatgg gagaacatttttgcacataatatatttaataataggctgacatccagaatacataaatacctacaactcaataccaaaaa gacagcccaatttaaaaatgggccaaggatatgaataaacatttctctaaagaagatacaaaaatggtcaatatgcacat gaaaagatgctcaatatcaatatctattaggaaaatacaaattaaaacacaaaatataaaacacaagatatcaatttaca ctcaccaggatggctgttatcaaaaagacagataacaagtattggcaaggatttggggaaattgtaaccttcatacattg ctggtaggaatataaaatttgcagcaggtttggaaaacagtttagcagtttctcaaaaagcctgggcatggtggctcatg cctacaatcccagtgctttagggagctgaggtgagaggattgcttgagcccaggagttggagaccagcctgagtaacaca gtgagacctcttttctaccaaaaagaagagagttaaacatagggtaccatataagccagcaatccatctcctagatatgt acccaagaaagttgaaaacatatactgacacaaaaacttacatatgaatcttcatattagccttataataatagccaaaa agtagaaacaacccaaatacccatcaactaattaaaatatggtgtatctatacatattatttggccataaaaggaagtac tgatacatgtcataacacaaatgaaccttggaagcactatgatctctgtattagtcagctcttgtattgctataaagaac tacctgagactgggtaacttataaagaaaaaggcttaattgagtcacagttccacaggctgcacagggatcatggcccag gagacctcaggaaacacagttatgatggaaggaagagagtgaaggaggaggtgctacatacttttaaaccaccagatctt gtgagaagtcactcactatcatgagaacagcaagggagaagtccacccccatgatccagtcagccccagccaggccccaa ctccaatattggggattacaattccacatgagatttgggtggggacactaatccaaacaatatcattctgccccagcccc tcccaaatcctgtgtccttctcacattggaagatacaa catcccttctcaacagtttcatttcagtattaactcaaaaa tccaaagtc catctgagacaagacaagtcccttccacctatgagcctataagatcaaaaagaagttagttacttccaag atacaatggaggtacaggcattgggcaaatatatccattccaaaagggaaaaattagccaaaacaaaggggccacaggcc ccacgcaagtccaaaatcaagcagggaaatcattaaatcttaaagcttcaaaatgatatcctttgactccatgtctcaca tccaggccacaccaatgcaaggagtgtgctcccaaggccttgggcagctctaccctgttgctctacagggtatagccccc atggctgctttcacaggctggcattgagtgcctccagcttttccaggtacacagtgcaagctgttagtggatctaccatt ctagggtctggaagattgtggccctcttctcatagctccagtagacagtgccccagtggggaatctgtatgggggctgca accccacatttctcctctgcactgcccaatagaggttctccatgagggctccattcctgtagcatacttctacctggaca tccaggtgttttcatacatcctctaaaatctaggtaggggctcccaagccttaactcttgccctctgcacatccgcaggc ttaataccacatggaaaccaccaatgcttatggcttgcaccctatgaagcagtagtctgagacatatctgggcccttttg gccatggctgggatgcagggaacagtgtcctgaagtggcacagggcagcggggccatgggcctggcccatgaaaccttct ttcctcctaggcctccagacctgtgatgggagggtctgcctcgacggtctctagaatgtgtttgaggcatattcctcatt gtcttggctattaatatttggctcctctttacttatgcaaatttctacagcctgattaattcctttccaaaaaaatgggg ttttcttttctactacatggtcaggtcacaaattttccaaacttttacgcttccctttgaaatgtaagttccagttgcag gtcatttctttgatcacaaatataagcatatatttgtagaatcagccaggccacatcttgaatgttttgctgcttagaaa ctgcttccaccagataccctaaatcattgctatcaggttcaaaattctacatatctctagggcaagggcacaatgcctcc aagacctttgctaatgcataagaaaattgacctttgctccagttcccaataagttccccatcttca ctgaggtctcctt agcctggacttcattgtccatatcagtatcagcattttcatcacaataatttaactagtctctaagaagttccaaacttt cccttatcttcctatcttcttctgagccctccaaactgctccaacctctgcccattacccgggttccaaagctgcttcca cattttcggtatctttatagcaatgctccattcctgataccaattttctgtattagtctcttctcgcactcctgtaaaga actacctgagactgggtaatttataaagaaaagaggtttaattgactcacagttccacaagctgtataggaagcatggtt cagaaggccacaggaaacttacaatcatggaggaaggcgaagagaaagaaggcacgtcttacgtggctggagtaggagga agagagtgaagggggaggtgttacacacttttaaacaaccagatcttgtgagaactcactcactatcatgagaacagcaa gggagaggtctgcctccatgatccaatcacctcctaccaggctcctcctccaacattggggattatgatttgacatgaga tttgggtagggacacaactccaaaccatatcaatcccatttatatgaaatgtccacaatagataaatctatagagacata aaatagattggtgcttgcctagtgctggacgtgacaggagggtgtgagtaaaagaggcaatggagtgataggtacagggt ttctttttggggtgatgaaaatattataaaattagattgtggttatagttgtataactcttgaatatcctaaaaatatat tgaattttccatttccattttaaatgggtgaatcttatggtatgtgaattatatctcaataaaactgcaaaaaatgcaca atttgcaattgcaaaaatatggaaccagtccaaatgcccatcaatgagtggataaaggaactgtggtatatatatatata tatatatatatatatatatatatatatatatatatatatatacacacacacacacaccatggaatactactcagccataa aagggaataaaacaatggcattctcagcaacctggatggaattggagaccattattctaagtgaaataactcagtaatgg aaaaccgaatatcatacattctcactcataagtgggagctaagctatgaggatgcaaaggcataagaatgatataatgga ctttgggaactcagggaaagggtgagagaggggtgaggaataaaaggctacccattgggtacagtgtacactgttcaagt gatggctgcaccaaaatctcagaaatcaccactaaagaacttatttacataaccaaataccacctgtttctcaaaaacct attgaaattaattaatttttaaaaactgctgaaatcaatagtgaaaggatggactattcaataatgacacagttaattga atatcatattttaaaaattagatccttacctcacactataacataacaataaattccaggtgaattatagaccaaatatg aaaagcaaaattttaatattttagaagacaatttttatgaccttaagttagaaaatgatttttaaaaacaggatgcaaaa acactaatcataaagagatattttaggccaagcatggtggctcacacctgtaatcctagtactttgggaagctgaggcag gtggatcacttgaggtcaggagttcaagacaagcctggccaatagggtgaaacatgtctctactaaaaatacaaaaatta gctggaaatcgctcgaacccaggaggcagaggttgcagtgagctgagattgtgccactgcactccagcctgggtgacaga gagagactccacctcaaaaaaataaataaataaaaataaagagagattttaataaggtgcattaaaataaaaaactatcc atcaaagacaccatgaataaagttaaaataggccacaatgagaatatatttgccatgaattttttctttttttttgagat ggagtcttgctctgtcacccaggctggagtgcagtggtgcaatctcggcttactgcaaacttcacctcccaggttcaagc aattctcctgcctcagcctcctgagtagctgggattacaggtgtgtgccaccatgcctggctaatttttgtattttttgt agacacggggtttcaccatgttggtcaggctgagctcaaacccctgacctcgtgatccaccttcctcagcctcccaaagt gctgggattacaggcatgagccaccgtgcctggcctaccatgaatatttttttaaaggtagcatccagaattaataatct tctccaacaaatttcattagtagtcagggaactgcaaattaaaatcaaagtaaaatactactttccactcattagactaa aatccattcaagtctgataatacctagtactgagttggagtaatagaaactgctaatgggacagttagttggtcatcact ttggagagaaattagtcagtatctagtaaaagttagtgatacaccttccattttcatctgttctgtgctgctaccaaaga atacctgagactaggtaatttataaataatagaaatgtatttctaatggttctagaggctgagaagtccaagattgaagg gccagcctctgcagagagccttcttgctgtgtcatgccatggcagaagggcaaagagagggcaagagagagcaaaagcaa attcacagcatcaatcccttttataatcagcattactctattaatgagggcaagaccctcatggcctaatcacctctaaa aggtcacacctcttaatactattgcaatggtaattaagtttctaatacatactttttgggagacattttcaaactatagc acctaccctatagcccaacatttctactcctaggagtatgccctagagaaattctgcataaatatctaaagagaggccat tgttgcattgttaggtactggaaaattggaatcaattactatgtctaccagcagcagaagatggctttttaaaagttttg gtttattcatgaaatggaatattgcataaagtatgctccatctcaccagatgaaaacatttttcactaggactatttcaa aagtagtcttatcactgggcttctctattatgcataaaaattttaagtgaacatgttctttgacctagtactcctacttt taggaatttgcccaaaagggacaattatactactgggataaatctttgaatcataaagtaagttgtaaatggtacaagca gtatgtcttatttttatttaaagcacattaacaatattacacatatagtaaaaaataaataaataaaacatgtgaataat aaacacccaatttagaacaagtgttgacagtggagagggaaagagagagaaagaaggagaaatggggagtgggagcgggt acacaaggaaattttagttgcagctccaaatttttactttttacacaatgaagcgaatatggcaaaataagatttgttaa agttgggcagcaggtacacagatattctatcattatcctttgaatatttctgtagatttaagttgtccattaaaaaaata aaatacacacataatttttaagattagttttttctatttcctggccttcgcatgcactgttaactttacctggaattctt tatgcagtaattaagagcaaaggtgtagagcaagactgcttgagcttggatcccagcactgagttgatttagggagaata acttaatctcttaatcccaagagaaaatatgatataatagttttgagctcataaagttttcataagcattaaatgtgacc tatatatgtaaagcaatctaacagtgcctatagtatttataagtgtctgcattaccaaattcatcat atcatggcatgt catgtcaccatccactacattaccatcactgtcaccatcatca catcaccaccaccatcatcattaactccctttgtct agtcaattcatatttgttcttcgtattttagatacctgttaaaatattttttcaaagatgtctactctgattcttcagta caaatttgatttaataagatcctatcattttgtccaaatacttataaaaatttgtagttctatatttaatgtgttttgtt tgtttaacatctctctcctacattgtgttaagttttttaaagagaaggtaagggttaaagagagacatagagagagaaag agagacagagagagagagagagcggttctacagcaatacaggtatattagaaaaacctgcaaaggtggggaccagcttaa tgccagagccccccactgcttataggctggggtacttataggtctgggggtacttataggcctgggtgggtggggtctga gcagtatggcttgctgcccaagaagatgttgataagacgttcccatgatgaggcagtttggtccttgcttccatagagtg tgatgcttcttgcactttttcccagcagaatgtggtagggatgttccttcaggtgggcctttgcctggcagggtatgata aggatgttcctgtgccttggaatcaggtagttagacaggatgtttctcacagcctgaacccccatggaatgtttcacttt gaccagggtctgcgaaatagcagggggcttacaaaatggtgtagtttggactaacaccttggaacacaaaagtttcttgg ggccaaggctggcgtattagtctgttttcatgctgctagtaaagacatacctgagactgggtaatttataaagagaaaag aggtttaatggactcacaattccacatggctggaggcctcacaatcatgagggaggcaaaggaggagcaaaggcacgtct tacatggtggtaggcaagagaacgtgtgcaggggaactgccctttataaaaccatcagatcttgtgatacttattcacta tcaaaagaacagcacgggaaaaatctgcctccatgattcaattacctcccaccagattcctcccatgacatgtggtaatt atgggaactacaattcaagatgaaatttgggtggggacacagtcaaaccatatcagctgggtatgttttattcaσctttt tatacccattgtcatgtcttctggacaaacaatggatgtaaaatggtatagactcctgagtactcatttgttgaatgaca aatctatgaaccatttgaccagtatgcagcagccattaaaattatgtttatgaataatttacagcatggaaaaatttggg gttgctagtagaaaaacaaaaaggtacaaaaggatatatataataagcctacaatgccatataaacaatactaacagcaa aaacaaacctataaattgggggaagatggggcagatagaagtaacctaaaatactaacatgttgttttggggtcatgaaa ttataaatgattatgcaccccttaatttttactttctatgtttgatttttctatggtaaatgcatttttattgaggtgga attcacataacatgaaatgaaaaatttagtggcatttattatattcacaatattgtacaaccactagctctacttccaaa acattttcatcactccaaaataaaaccttgtacccattaagcagttactccccattatttcctctcttagctcctagcaa ccaccaacctgctttctgtctctagggatttatttattctggatattccataaaaatggaggcacaatatgtacctttta tgtctggcttctttcaccaagcatgtttttgaggctaatccacattgcagcatgtatcagtacttcatttctttttatga ataactgtatacagaccacaatttgttatccattttttggtttatggacatttgggttgtttccatctctcaactattgt gaatagtgctgctatgtatatttgtgtacaagaatttggttacctattttcaattcttttatgtatatatctaagatgaa attgcagggttatatgctaatcctatgtttagcatttttttttaggaaccattaaactgttttccaaatctgatgcccca ttttatattcctactagcaatgtaagcaagttccaatttctccatatcctcaacaacacttgttattttctatttttgtt atagccattctaatgagtgtaaagtgatatatcattgtggttttctttgcattttccttatgaacattgatgttgagtac cttttcatgtactttttggtcatttatatatcatctttggagaaatgcctcttcgtgtatgttttgcccattttaaaact agattgtctttgttgttgacatgcatgcattctttaaatattctgcatactaggcccttatcagatatatgatttgcaaa tgttttttctcattttactggctgtcttttcactttattgataatgtcctttgatgcccaaaagttgtttattttgatga agcatatttatcaatttatttcttttattgctcatgcttttgatgtcacctctaagaatttataaccaaatcagaggtaa 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tataaatgccttctaaatacctgtcttggcctatccccagccacagattcctccctagagcaggctacctctgaggcatc tatactgagatcttaatcacagagacatttaaaacatctaggctacaaaagaattcctactatagggttcaaatgaattt ctttccgtcacttgagacagctttttagcaagtacatgtattaaagattctgatttccccttttttctcctacagtttgt ttggcctaaaggtatgacatctaatctgctgcatttacactctaagtcaaaattaccattttgttcttttaatttctatt tctaatcatacattcttgtctactcctggttcatctggagacaaagttgaacttagaagatggaggagaaattcttatct gccctctgctagttgacacttcctttccaagaatcatttgcagttgctgggctttcttgctgtgactctatgccctgttg tgttactttttcatttgtgacaaaaacagtggtaatagtttgcttcatttttattatgaagacttgaccaggataggtag gaacataattactgctttttctgtgggcatcatattggtccagatcatgtttaaccagaattgaagatgtaaaatcctag aactcactaatctattttagtaggtcacaggaagcatgcaaaccataaaaaccgcaatgaaccaaaagcatctgtgttga caagaggcaagaatttctctattttctaaaggcactaactgaacaaatctattgcccattacttaggaaattgctaaggg catcgttaaagtacttcaggctgttgaaaaaccttttctgtcttcttgccccaccaccaattctctctagctatgctttc tctcacatgttcttgccatccatggagtggcagagaggttctgagtacaactctaactttcagtttcaatggcctaatcc 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caaaaaaaaaaaaaaagaaggcagaaggtgaatagttcaagggtgggtttaggactcagtgataataggattctgcctgg cttctcatggttctctaggtcttccattcatggcaccatgccctcactaggcatgctgccagagcaggaggggcaggtgg agggttctcttgtgtctgtcttatcagggaagaagagctttctcagaagcccccagcagactcccttttcatattatggt ccagcaatgagtcacagacctatgcaccacctgcaaaggagccagagaaaacaaacgcccagcgcttttagcctgaaaat gagaatctggtttgctggggaagataaagggtgtcggaaaatggctgttgggtaaatcattgatgtctgccactaggaat gaaaggcaaatcaggaactggcacacatgctttcagggagatggctgcaagggagagggcaaagactgggaagttgctta tgtggtgccagactatttggaagatcatggattgcggtgtttgtgttgtgtggtcatcattttgttctttgtttacagaa cagagaaagtggattgaacaaggacgcatttccccagtacatccacaacatgctgtccacatctcgttctcggtttatca gaaataccaacgagagcggtgaagaagtcaccaccttttttgattatgattacggtgctccctgtcataaatttgacgtg aagcaaattggggcccaactcctgcctccgctctactcgctggtgttcatctttggttttgtgggcaacatgctggtcgt cctcatcttaataaactgcaaaaagctgaagtgcttgactgacatttacctgctcaacctggccatctctgatctgcttt ttcttattactctcccattgtgggctcactctgctgcaaatgagtgggtctttgggaatgcaatgtgcaaattattcaca gggctgtatcacatcggttattttggcggaatcttcttcatcatcctcctgacaatcgatagatacctggctattgtcca tgctgtgtttgctttaaaagccaggacggtcacctttggggtggtgacaagtgtgatcacctggttggtggctgtgtttg cttctgtcccaggaatcatctttactaaatgccagaaagaagattctgtttatgtctgtggcccttattttccacgagga tggaataatttccacacaataatgaggaacattttggggctggtcctgccgctgctcatcatggtcatctgctactcggg aatcctgaaaaccctgcttcggtgtcgaaacgagaagaagaggcatagggcagtgagagtcatcttcaccatcatgattg tttactttctcttctggactccctataacattgtcattctcctgaacaccttccaggaattcttcggcctgagtaactgt gaaagcaccagtcaactggaccaagccacgcaggtgacagagactcttgggatgactcactgctgcatcaatcccatcat ctatgccttcgttggggagaagttcagaaggtatctctcggtgttcttccgaaagcacatcaccaagcgcttctgcaaac aatgtccagttttctacagggagacagtggatggagtgacttcaacaaacacgccttccactggggagcaggaagtctcg gctggtttataaaacgaggagcagtttgattgttgtttataaagggagataacaatctgtatataacaacaaacttcaag ggtttgttgaacaatagaaacctgtaaagcaggtgcccaggaacctcagggctgtgtgtactaatacagactatgtcacc caatgcatatccaacatgtgctcagggaataatccagaaaaactgtgggtagagactttgactctccagaaagctcatct cagctcctgaaaaatgcctcattaccttgtgctaatcctctttttctagtcttcataatttcttcactcaatctctgatt ctgtcaatgtcttgaaatcaagggccagctggaggtgaagaagagaatgtgacaggcacagatgaatgggagtgagggat agtggggtcagggctgagaggagaaggagggagacatgagcatggctgagcctggacaaagacaaaggtgagcaaagggc tcacgcattcagccaggagatgatactggtccttagccccatctgccacgtgtatttaaccttgaagggttcaccaggtc agggagagtttgggaactgcaataacctgggagttttggtggagtccgatgattctcttttgcataagtgcatgacatat ttttgctttattacagtttatctatggcacccatgcaccttacatttgaaatctatgaaatatcatgctccattgttcag atgcttcttaggccacatccccctgtctaaaaattcagaaaatttttgtttataaaagatgcattatctatgatatgcta atatatgtatatgcaatatatataggctcttgcttgatctctccaggaggtagtgattatgagaagggggtggagaatga tgagttccttcaccaggagcaaaggacggggatcgtgtggaaccactgcagaactatttccggaatcaactaagtggaga gagccaggaaggctgcatcagaacccagtaaagcttcttgtctggatctgagctggtttgttttgtgcttgcttttccct gccttgccactcccctcactcttctcttttccccacagcctttttcacatagctcttggctgtaggattgccccactcca aaaaccagtgtgtggaggtccaggagtgagaccaggaaagaatgtgaaagtgactacacaaggactcctcgatggtcgtg gaaaaggaaagtcaattggcagagcccctgaagccagtcttcaggacaaagaaggagcctagagacagaaatgacagatc tctgctttggaaatcacacgtctggcttcacagatgtgtgattcacagtgtgaatcttggtgtctacgttaccaggcagg aaggctgagaggagagagactccagctgggttggaaaacagtattttccaaactaccttccagttcctcatttttgaata caggcatagagttcagactttttttaaatagtaaaaataaaattaaagctgaaaactgcaacttgtaaatgtggtaaaga gttagtttgagttactatcatgtcaaacgtgaaaatgctgtattagtcacagagataattctagctttgagcttaagaat tttgagcaggtggtatgtttgggagactgctgagtcaacccaatagttgttgattggcaggagttggaagtgtgtgatct gtgggcacattagcctatgtgcatgcagcatctaagtaatgatgtcgtttgaatcacagtatacgctccatcgctgtcat ctcagctggatctccattctctcaggcttgctgccaaaagccttttgtgttttgttttgtatcattatgaagtcatgcgt ttaatcacattcgagtgtttcagtgcttcgcagatgtccttgatgctcatattgttccctattttgccagtgggaactcc taaatcaaattggcttctaatcaaagcttttaaaccctattggtaaagaatggaaggtggagaagctccctgaagtaagc aaagactttcctcttagtcgagccaagttaagaatgttcttatgttgcccagtgtgtttctgatctgatgcaagcaagaa acactgggcttctagaaccaggcaacttgggaactagactcccaagctggactatggctctactttcaggccacatggct aaagaaggtttcagaaagaagtggggacagagcagaactttcaccttcatatatttgtatgatcctaatgaatgcataaa atgttaagttgatggtgatgaaatgtaaatactgtttttaacaactatgatttggaaaataaatcaatgctataactatg ttgataaaagatttaaaaacaactggctgtttttttacactgtggtgtggaagattgtgttgtgttcacaacttttcact tcttcccctgtgtgattacacacacctgcccttgtggtgtgacttgcagtgcgccctacaggccacacaaccccatgccc tccaccactggctctgctgctggaatgtgagcagaagtgacatctgcctcatccaagcagagcctcttgctcagccacag gaaggcccattccagatcacacccgtcagcccgtgcgccctggtgaatgagaagacacagggagctgcagccacatataa catgagcaagaagtctgtgtttgctgtgataagccactgagttttaggggttgtttgttaagaagcacaaaaaccgatta agacatgtggtatatagtgacttcatatatagaatctggaaaactatccatttattttcaatcatggaattcaatatgac aagcatcccggagggtctacctatgccagactgggttggaaacagaaagacagatgttaatgccagtgtcctttacacct ccaagtccagggccagctgtggagtgggaggggtagagaaggtcctgtgcacagtcacagtgcgctgtgcagagcaggaa cagaggcatctgtgaaaagtgctgagagcctggaggacagagtgactaatgcaatgacagtcttgcatcataggaataac agccacagcaggattttattgctgccaaagaaactgccatttaaaaattgccagccatccgggaggctgaggcaggagaa tggcatgaatccaggaggcggagcttgcagtgagccgagatcgggccactgcactccagcctgggcaacagagccagact ccatctcaaaaaaaaaaaaaaatgccagccatctctctttctaaagtggaatcctcaagtctcgtttattctggggacat ttgagtaggctgttcgagttaagcaggtggaagttgatgatccctcatcatcattctgagggatgagtgtctgaagactt tttggtaaggaagggtct'tggcatagcccaccccatgccacctcccttgatctgtgatatccccagcagctggggaggtt ggagcattttgcaaagaggccccgaagcctccagaaagtaaaccttcaagagcccatccttccttcctcttttgtttttg ctcattatgaaaacttccctgacaaattgaaaaggcttcaggtgagattagcccacaggaaaaaccaccaagggccaccc agaggggccacactgtgacagaaggagtatgggctggtgagctgacctctggaagacagtgcatgaattgaggagaagag attggttccaggcatgggaggaatgaggctggaaatttcttcagacattgccacttcggcactctgtgtgtgtgtgtgtg tgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtaaacagagtcctgtaatgcaaggtccggccttggcagccccag cctggagccacagtgagatgtgagctgagggttatgctgggaaaaacctctccctcccagcacctgaaaggctctgcagg cccagcagctcagcaagcaagggtaagggcatggactaacatcttatttcatactatcccttataacacatcctaatgta atcagctcacaatatgaaattatttcatttctctccagtcattgtttcaatggggccttagggttgactggattctggag gtccctgcctagaggagggggtgcattctgtccctatgtcccctcctgctccatcctccacagcacgtgcctagtggtct accttgtggggaattcttgtacctccctcttctaggcatggactagcattgagaagtgggagaggagtgttaggaaaaag ggcaaatatagacataccttgtcttattgtgctttacagatattgtttttgttgttgttgttgttgtttacaaattgaag gtttgtggcaaccctgcctcgagcaagtctattggtgctgtttttccaacagcatgtgcttgttttacatctctgtgtca cattttggtaattctcccaatatttcaaactttgtcattatttctatatctgttatggtaatctgtgatcagtgatcttt gatgtcactattgtagttgttttggggcaccatgaagtgcacccatgtaagatggcaaacaatcaataaatgttgtgtgt gttctgactgctccatggactgcctgttcctgagacacaataatgtatatataacaattatatatatatatatttataac aattatatatatatatattttttttttttttttgaggcagagtcgcactctgattgcccaggctggagtgcaatgatgtg atttcagctcactgcaacctctgcctccccaggctcaggtgattctcccacttcagcctcccaagctgggactacaggtg tgcaccatcacacccggctaattttttttttgtatttttaggagagacagggttttgccatgttgcccaggctggcctta aactcctagactcaaacaatccacctgcctcagcttcccaaagggctgggattacaggcatgagccactgtgcccagccc aagacacaataatattgaaattaagccaattaataaccctacaatggcctctaagtgttcaagtgaagggaaaagtccca cgtctctcactttaaatcaaaatctagaaatgattaagcttagtaaggaggacatattgaaagtcaaggccaaaagctca cctctgcaccagttagccaaattgcgacttcacaggaaaagttcttgaaggatatttaagctctactccagggaacatgc aaatgaagagaaaacaaagcagccatattgctaatatggagaaagtttgagtggtctggagaaaagatccaaccagccac aacatttccttaagtcaaagcctaatccagagcaagactctaactctcttcaatgctatgaaggcggagagaggtgagga agctgcagaagaaaagtttgaagctagcggaggttggtttgtgaggtttaatgaaagacaacatctccataacataaaaa tgcaagatgaagcagcaagtgcaaagggagaagctgtggcaagttatccagaaaatctagataagataattgatgaaagt gtctacacgaaacaacagattttcagtgtagacaaaacagtcttatgttggaagaagatgccatccaggactttcacagc tagagaggagatgtcaaggcaagctgcaaagctccacaggacaggctgactctctttttagaggtgaatgcagctgatga ctttaagttgaagtaaatgttcatttactattttgtaaatcctggtgtcattaagaattatgcgaaatctactctatctg tgctccataaatggaacaataaagcctggatgacaacacatctgtttacagcatggtttactgaatatttcaagcccact attgagaactattgctcagaaaaaaagattcctttcaaaatattactgctctgcaccatgtcgatcaagagctgtgttgg agatgtacgagaatattcatgttgttttcatccctgctaacacaaacatccattctgcagtccatggaccaagactttca agtcttattaagaaatatatttcataaggctattaagaaatagctatatatatatatatatatagccttatatagtttat atagctaccattgatagtgattccattgatggatctgagcaaagcaaattgaaaagcttctggaaagtagtcattattct agatgccattaggaacatttgtaattcatgggaggaggtcaaaataccaacattaacaggagtgtgaaagacattgattc caacccccatagatgactttcaggggttcacgtcttcagtggaggaagttgctgtagatgtggtggaaacagcaagagaa ctagaactagaagtggagcctgaagttgtgactgaattgccgcactctcatgatcaaacttgaacagatgaagagttgct tcttacatatgagcagtgaaagtggtctcttgagatggaatctcctcctggtgaagatgctgtgaacacggttaaaatga caacaatcgatttagaatattacataaatttagttaataaagcagtggcagggtttgagaggattgactccaattttgaa agaagtgggtaaaatgctatcaaatagcatcacatggtatggagaaatcttttgtgaagggaagagtcgaccaaggtggc aaattgcattgtcatcttattttaagaaattgccacagccacccccagctttagcaaccaccaccctgatcagtaagcag ccatcaacatcaaaacaagaccgccatcctcttcagcaaaaacactatgacttgctgaaggctcagatgatggttagcat ttttagcaatacaatatttttaattaaggtatgcacattggtttttctgaCataatactattgcatacttaatagactac agtataggataaacacaacttttatatgcactgggaaaccaaaaaggttatttttgagatatttgctttactgtggtggt ctgaagctgaactcacaatctcaccaaggtgtgcctgaacctctttagctaactggccactgccacagtccactctgtgt tggtcaagatgccccagagtggcaggcacactgtgtggtcacatccaagggcctagatatggtgggggctccaaatggat ctagatatgtgagatctctctttgatttgacttcttccaacccaccattttctgggtgctgggctcatctcacccagaaa gtaggacccaatgtgacagttcctgcccagttccctcctgtggtagccacttgacccaggggcactcttgatccttgcag cctcacttacacaccctatctctacccctattaactctctccaatccccactccccctgctcagcttgtctgctgcccag tgggggccccacccatgctggcctctccttttgcaagtccccattcctcatatggtttcttcagagcccctttctttggc tttgaggagagatgccctcactcgcttccccaccaatcctgcccacttctacaatccattcattatcctaattgcctccg tatacagactggagtgagaggagttgatgtgatgggtgtggatacagggctggtgctg catcttctagtaagccctggg ^ag^a9gtgtctgagcccaggtgtcagtggttttctttggaactgtgagtgcataacacttctttgccttcagccttaggcc atagttgctagttctgggacaaccagaaaagccctacataatctcgtgttatgtgcagagctgagtatagagctccaggt atgatctgactcacttaagatcacagtgagtctattgtattgttgaactgttagcttagacatctgttactgtacctaca tggcactagcctcacgcctagacaccgatctgaaagaaatcccctaaatgcatagagaagacttctcagctgagctaagg ggctcccaccaggtttgagcctatctaatgaatccatgaggtagacagcctgcacatgtccacttggtttgatgaattgc acaaatccctatgggggatgtggttcatgggctgggaagtgggttaccctgggaaaggtctacaggacagaggcagggat ggagacaacagcatggtgagttcccaacccacccacgatgataggtgtctgaggcagaaggtaaagaggctgtcacctgg tgggtgtcataagactcaagtgtcattgttgaggcacatgggtaacaaagcgtggcactggatgggggtagattcttcct atttctgtgaggatcagggggactccctggctctcctgctaaaggtggctctagggacaggaagagtgtacttcttgaca gggatgtcagagcactgatggtgacaatcagtgtgacactgctcacatgactgaacaaccgagaagagcccgactgtcta ctgaacaacgggaagagcccgactgtcaatgacggagctctgttaaatatagttaaggctattttgttgaatgaatgaag ccagacaggaaagaggacagtatctttaatccatttatagaagttaaagacaggcttatttaatctctatgaagacagag tggcccttacctctgggtggagcaaaaggcaccttctgaagtgatagggatgttccttatcatcttgatccggagtggta gttacatgcatgtatgcatatcaaaactcaccaagctgtaccactaagtgtgttcttcctcaataaaaataataaagaac tacacttataaagaattttttaataatataggaaaatgtctacactataatctttagctaaaaaaaaaaaaaaagaagcc gcctacagaatggtatatgcatgagaacaattaatcgaaaagtgcatgggaaaagtcaggattgaaacatcatgttttaa aagacattgttttgatactgtgagaatgtacctaagtttttccttttttctgtttttcccaattttatacaatgagcatg tgttggttttataattagacattttgtttgtttggtttggttttgagacacagcttgctgtcacccaggttggagtgcaa tggcccaatcttggttcactgcaacctccatctcctgggttcaagagattctcccacttcagcctcctgagtagctggga ctataggggcgcaccaccacatccagctaattttgtgtatttttagtagagatggggtttcaccatgctggccaggttgg tctcaaactcctgacctcaagttatccactcgccttggcttcccaaagtgctgggattataggcatgagccaccgcactt ggcctagacatttgtttttaaaaataaaagattcatttgctctttttacagcccgtctcactgttgactgatattgacca ggagtcaactcaggccccagggattttcacaacagctgctgtatggcagggtttctgctcactgtgctcatgtagttggc ccttgcacccaaagtgaataattaacattctccccatcctgttgacgatgctctgaaaatatggtccagaaatggtgtga gcaaggagacagcaaagcaatgcttggaacataggtgcagtgactagacatggggcagctgtttaaagacaaaaaggccc caaaaaggagggatggcacgaaacaccctccaatatgggcatggagtctagagtgacaaagtgatcaaaagttcatttcc tatggggtgtccgaatgtacttaataataaaaagagaacaagagccatgcaaactgagagggacaaagtagaaagagtag cagacaccaagcaactaagtcacagcatgataagctgctagcttgttgtcattattgtatccagaacaacatttcattta aatgctgaagaatttcccatgggtccccactttcttgtgaatccttgggctgaacccccctgtcctgagtggttactaga acacacctctggaccagaaacacaaaagtggagtaacacacactgcaaagctgtgcttccttgtttcagcctgtgaatcc tcaccttgtttcccatctagcctatatttttcaaactaacttggccatagaatcatgtagtatttagggtggaagctgcc ccaggtctagcacgtcatttaacagatgaggaaatggaagcttgggcagtggaagtatcttgccgaggtcacacagcaag tcagcagcacagcgtgtgtgactccgagcctgctccgctagcccacattgccctctgggggtgagtatgtcttcacatcc tccaataccctaatgacagacaaacagaacatggcaaagcctcagctctgcatggtgaaagtaagaaccagcaattgcca caaacagaaatacagtgttggtccggcagcctccgggggttctgcacaagtggattaccagtgaatacaaggctatctat ctttcgaaaaaccaacgttgtatttatgctattttctataaaattttatattaatttatttgttacctatttttgaactc tttcaaaagcacactttatatttccctgcttaaacagtcccccgagggtgggtgcccaaaaggctctacacttgttatca ttccctctccaccacaggcatattgagtaagtttgtatttgggtttttttaaaacctccactctacagttaagaaaacta aggcacagagcttcaataatttggtcagagccaagtagcagtaatgaagctggaggttaaacccagcagcatgactgcag ttcttaatcaatgccttttgaattgcacatatgggatgaactagaacattttctcgatgattcgctgtccttgttatgat tatgttactgagctctgttgtagcacagacatatgtccctatatggggcggggttgggggtgtcttgatcgctgggctat ttctatactgttctggcttttcccaagcagtcatttctttctattctccaagcaccagcaattagctttaccttttcagc ttctagtttgctgaaactaatctgctatagacagagactccggtgaaccaattttattaggatttgatcaaataaactct ctctgacaaaggactgctgaaagagtaactaagagtttgatgtttactgagtgcatagtatgtgctagatgctggccgtg gatgcctcatagaatcctcccaacaactcatgaaatgactactgtcattcagcccaatacccagacgagaaagctgaggg taagacaggtttcaagcttggcagtctgactacagaggccactggcttagcccctgggttagtctgcctctgtaggattg ggggcacgtaattttgctgtttggggtctcatttgccttcttagagatcacaagccaaagctttttattctagagccaag gtcacggaagcccagagggcatcttgtggctcgggagtagctctctgctgtcttctcagctctgctgacaatacttgaga ttttcagatgtcaccaaccaccaagagagcttgatatgactgtatatagtatagtcataaagaacctgaacttgaccata tacttatgtcatgtggaaaatttctcatagcttcagatagattatatctggagtgaagaatcctgccacctatgtatctg gcatagtgtgagtcctcataaatgcttactggtttgaagggcaacaaaatagtgaacagagtgaaaatccccactaagat cctgggtccagaaaaagatgggaaacctgtttagctcacccgtgagcccatagttaaaactctttagacaacaggttttt tccgtttacagagaacaataatattgggtggtgagcatctgtgtgggggttggggtgggataggggatacggggagagtg gagaaaaagggggcacagggttaatgtgaagtccaggatccccctctacatttaaagttggtttaagttggctttaatta atagcaactcttaagataatcagaattttcttaaccttttagccttactgttgaaaagccctgtgatcttgtacaaatca tttgcttcttggatagtaatttcttttactaaaatgtgggcttttgactagatgaatgtaaatgttcttctagctctgat atcctttattctttatattttctaacagattctgtgtagtgggatgagcagagaacaaaaacaaaataatccagtgagaa aagcccgtaaataaactttcagaccagagatctattctctagcttattttaagctcaacttaaaaggaagaactgttctc tgattcttttcgccttcaatacacttaatgatttaactccaccctccttcaaaagaaacagcatttcctacttttatact gtctatatgattgatttgcacagctcatctggccagaagagctgagacatccgttcccctacaagaaactctccccggta agtaacctctcagctgcttggcctgttagttagcttctgagatgagtaaaagactttacaggaaacccatagaagacatt tggcaaacaccaagtgctcatacaattatcttaaaatataatctttaagataaggaaagggtcacagtttggaatgagtt tcagacggttataacatcaaagatacaaaacatgattgtgagtgaaagactttaaagggagcaatagtattttaataact aacaatccttacctctcaaaagaaagatttgcagagagatgagtcttagctgaaatcttgaaatcttatcttctgctaag gagaactaaaccctctccagtgagatgccttctgaatatgtgcccacaagaagttgtgtctaagtctggttctctttttt ctttttcctccagacaagagggaagcctaaaaatggtcaaaattaatattaaattacaaacgccaaataaaattttcctc taatatatcagtttcatggcacagttagtatataattctttatggttcaaaattaaaaatgagcttttctaggggcttct ctcagctgcctagtctaaggtgcagggagtttgagactcacagggtttaataagagaaaattctcagctagagcagctga acttaaatagactaggcaagacagctggttataagactaaactacccagaatgcatgacattcatctgtggtggcagacg aaacattttttattatattatttcttgggtatgtatgacaactcttaattgtggcaactcaaactacaaacacaaacttc acagaaaatgtgaggattttacaattggctgttgtcatctatgaccttccctgggacttgggcacccggccatttcactc tgactacatcatgtcaccaaacatctgatggtcttgccttttaattctctttttgaggactgagagggagggtagcatgg tagttaagagtgcaggcttcccgcattcaaaatcggttgcttactagctgtgtggctttgagcaagttactcaccctctc tgtgcttcaaggtccttgtctgcaaaatgtgaaaaatatttcctgcctcataaggttgccctaaggattaaatgaatgaa tgggtatgatgcttagaacagtgattggcatccagtatgtgccctcgaggcctcttaattattactggcttgctcatagt gcatgttctttgtgggctaactctagcgtcaataaaaatgttaagactgagttgcagctgggcatggtggctcatgcctg taatcccagcattctaggaggctgaggcaggaggatcgcttgagcccaggagttcgagaccagcctgggcaacatagtgt gatcttgtatctataaaaataaacaaaattagcttggtgtggtggcgcctgtagtccccagccacttggaggggtgaggt gagaggattgcttgagcccgggatgatccaggctgcagtgagccatgatcgtgccactgcactccagcctgggcgacaga gtgagaccctgtctcacaacaacaacagcaacaaaaaggctgagctgcaccatgcttgacccagtttcttaaaattgttg tcaaagcttcattcactccatggtgctatagagcacaagattttatttggtgagatggtgctttcatgaattcccccaac agagccaagctctccatctagtggacagggaagctagcagcaaaccttcccttcactacaaaacttcattgcttggccaa aaagagagttaattcaatgtagacatctatgtaggcaattaaaaacctattgatgtataaaacagtttgcattcatggag ggcaactaaatacattctaggactttataaaagatcactttttatttatgcacagggtggaacaagatggattatcaagt gtcaagtccaatctatgacatcaattattatacatcggagccctgccaaaaaatcaatgtgaagcaaatcgcagcccgcc tcctgcctccgctctactcactggtgttcatctttggttttgtgggcaacatgctggtcatcctcatcctgataaactgc aaaaggctgaagagcatgactgacatctacctgctcaacctggccatctctgacctgtttttccttcttactgtcccctt ctgggctcactatgctgccgcccagtgggactttggaaatacaatgtgtcaactcttgacagggctctattttataggct tcttctctggaatcttcttcatcatcctcctgacaatcgataggtacctggctgtcgtccatgctgtgtttgctttaaaa gccaggacggtcacctttggggtggtgacaagtgtgatcacttgggtggtggctgtgtttgcgtctctcccaggaatcat ctttaccagatctcaaaaagaaggtcttcattacacctgcagctctcattttccatacagtcagtatcaattctggaaga atttccagacattaaagatagtcatcttggggctggtcctgccgctgcttgtcatggtcatctgctactcgggaatccta aaaactctgcttcggtgtcgaaatgagaagaagaggcacagggctgtgaggcttatcttcaccatcatgattgtttattt tctcttctgggctccctacaacattgtccttctcctgaacaccttccaggaattctttggcctgaataattgcagtagct ctaacaggttggaccaagctatgcaggtgacagagactcttgggatgacgcactgctgcatcaaccccatcatctatgcc tttgtcggggagaagttcagaaactacctcttagtcttcttccaaaagcacattgccaaacgcttctgcaaatgctgttc tattttccagcaagaggctcccgagcgagcaagctcagtttacacccgatccactggggagcaggaaatatctgtgggct tgtgacacggactcaagtgggctggtgacccagtcagagttgtgcacatggcttagttttcatacacagcctgggctggg ggtggggtgggagaggtcttttttaaaaggaagttactgttatagagggtctaagattcatccatttatttggcatctgt ttaaagtagattagatcttttaagcccatcaattatagaaagccaaatcaaaatatgttgatgaaaaatagcaacctttt tatctccccttcacatgcatcaagttattgacaaactctcccttcactccgaaagttccttatgtatatttaaaagaaag cctcagagaattgctgattcttgagtttagtgatctgaacagaaataccaaaattatttcagaaatgtacaactttttac ctagtacaaggcaacatataggttgtaaatgtgtttaaaacaggtctttgtcttgctatggggagaaaagacatgaatat gattagtaaagaaatgacacttttcatgtgtgatttcccctccaaggtatggttaataagtttcactgacttagaaccag gcgagagacttgtggcctgggagagctggggaagcttcttaaatgagaaggaatttgagttggatcatctattgctggca aagacagaagcctcactgcaagcactgcatgggcaagcttggctgtagaaggagacagagctggttgggaagacatgggg aggaaggacaaggctagatcatgaagaaccttgacggcattgctccgtctaagtcatgagctgagcagggagatcctggt tggtgttgcagaaggtttactctgtggccaaaggagggtcaggaaggatgagcatttagggcaaggagaccaccaacagc cctcaggtcagggtgaggatggcctctgctaagctcaaggcgtgaggatgggaaggagggaggtattcgtaaggatggga aggagggaggtattcgtgcagcatatgaggatgcagagtcagcagaactggggtggatttggtttggaagtgagggtcag agaggagtcagagagaatccctagtcttcaagcagattggagaaacccttgaaaagacatcaagcacagaaggaggagga ggaggtttaggtcaagaagaagatggattggtgtaaaaggatgggtctggtttgcagagcttgaacacagtctcacccag actccaggctgtctttcactgaatgcttctgacttcatagatttccttcccatcccagctgaaatactgaggggtctcca ggaggagactagatttatgaatacacgaggtatgaggtctaggaacatacttcagctcacacatgagatctaggtgagga ttgattacctagtagtcatttcatgggttgttgggaggattctatgaggcaaccacaggcagcatttagcacatactaca cattcaataagcatcaaactcttagttactcattcagggatagcactgagcaaagcattgagcaaaggggtcccatagag gtgagggaagcctgaaaaactaagatgctgcctgcccagtgcacacaagtgtaggtatcattttctgcatttaaccgtca ataggcaaaggggggaagggacatattcatttggaaataagctgccttgagccttaaaacccacaaaagtacaatttacc agcctccgtatttcagactgaatgggggtggggggggcgccttaggtacttattccagatgccttctccagacaaaccag aagcaacagaaaaaatcgtctctccctccctttgaaatgaatataccccttagtgtttgggtatattcatttcaaaggga gagagagaggtttttttctgttctttctcatatgattgtgcacatacttgagactgttttgaatttgggggatggctaaa accatcatagtacaggtaaggtgagggaatagtaagtggtgagaactactcagggaatgaaggtgtcagaataataagag gtgctactgactttctcagcctctgaatatgaacggtgagcattgtggctgtcagcaggaagcaacgaagggaaatgtct ttccttttgctcttaagttgtggagagtgcaacagtagcataggaccctaccctctgggccaagtcaaagacattctgac atcttagtatttgcatattcttatgtatgtgaaagttacaaattgcttgaaagaaaatatgcatctaataaaaaacacct tctaaaataattcattatattcttgctctttcagtcaagtgtacatttagagaatagcacataaaactgccagagcattt tataagcagctgttttcttccttagtgtgtgtgcatgtgtgtgtgatgtatacaaagagagagataattgtatttttgta ttttcttttaaataatttttaaaattgacccttttcctgagacaaattgccagaatagtttgtatttagagatggtacct ctaagagtaaggttgctggttgctgagcaattgacttgaaaacttttaaaattcaaattttaattccactactcaaaaga attgccatgttttaaaaaagagaattggtgccataagttagttgtctatgtttgaaaatgaagaagatatgcaacgtcat ggcctggtcacttacccgcagccctgagttgtaggcacatcatatgtgagaatgaggatgcttttctttcatttaaaatc cctccccaaaacttggctctaattgcagtcatgacaatcatgtacatttggatttatgtgcacgagtctcttaccctgag agaggacaggtgctacaggtggaggggacccgtctgggtcacgttcacattttgaacatgctggttttcagtcactgcac actcatctcccagcgcaggtcatgggcagcagatgcaaaagctgcccgtggtcctatttggaggtgcatgaaatgagcag aagacagaatagcttgatctgactagaagggcagcttgtccctaccaagacttgaaggattgcctttcatctgttagggt aaaaggtagaatgaaccaaggaagggcaggagggggctggggttagggtagaaggaaggggccatggagaagggagatcc atcccataggaggaaggcagtgcggcagggaggtttgaaggtatcagcttttgtggctgacatacatgcagtcatgtcaa ttgctcgtttttccttttccatcttattaaatgtcttccaatgttagcacgaagaaaagctatttgcagtgttgccagcc tttccagagcccgtccccattacctccccaggcccatgcctttactccttggagtttcaactcacgaccttcaggatctg actttattcaccaactctggggtgaacgtaccttctgtctccacccagaggtctctatcaaagaggagattgcatgccat ggataaagtcaaagtagaggtgactgtccttaggaagagtaatgtgaaaattcataaactgggattctgtttacattttg tactccaggggttcttagtttaaatcgctctgaataaattaagatgcaatggcatttcaactgttatgattaaatttaca aatcatttattttctatcacggggagagatagagctccaaatgcaaacataactgctcaagtgttaacacttataatgaa aacataagaattaccaccaactaccctgggggctagaagcagaaatgtgaaccagaaaacaaatcatgaactttcctttt tttttttgagatggagtctcgctctgttgcccaggctggagtgcaatggtgcgatctcggctcactgcaaccactgcctc ccgggttcaagcaattctcctgcctcagcctcctgagtagctgggactacaggcatgcaccaccacgcctgggtaatttt ttgtatttttagtagagacagggtttcaccgtattagccaggatgctctcgatctcctgacctcgtgatctgcccgcctc ggcctcccaccgaagtgctgggattacaggcatgagccactgtgcccggccaacaaatcatgaactttctaactgcagtt ccttgtagcttgttaacacatccacttacttattgtcagagtacgtggagattttccacaaccctcggggataaggctga acagaagaggcaaaaacgtgaaaacatttcgatagctcctatactttgaaataaaattcactgtaaaagttgcttgtatt tttccaaaacagagtcaacccttaatatttaagattctgtatacaaatacatatttttatataattaatatatattgtca tatgacatatatctttatattaatatgcatgcatataatatatatttccttcctaattttctataagcaattttacaaga ctgacttctatttgcctccttattgttactacgtggtttgataatccgttttgtgtcattgtgattctgtcatgttttgg ggacttatttttgtttctctgggtggtcactagtttttttaaagcattcatggaagagtgtgaatcttttacaagctagg aagccatggcaagccttgggtcatactgcccccgcgaggccacattggcaaaccagcaagggtgttcaacttccagactt ggccatggagaagacatacgaggaggcttttcacattcagctctttaatgtttgtctctgccggcaccatcccagttgtg aataagaggtatttccacagcggctcagggtaggtagtgcacagctcacattcatcatttctgaaaaccgagaggagtct ccattcggggtacaggttgatgcctgtcgtggaatgaaggttccaacacccagaccaatctctgcagtgtgctgctctca tgagcttgcaacaagatcagaaaatgttttgtgactaagcatttttcatattgcataaaatgcttcaagctcctcccttg tttctctctataatcctgtatatctgatgattgtgggtaccaagtgtttgaaataatcaaatgtgatttgatgttggtaa atttctttttttttttttttttacttctattttttttattatactttaagttttagggtacatgtgcacattgtgcaggt tagttacatatgtatacatgtgccatgctggtgcactgcacccactaactcgtcatctagcattaggtatatctcccaat gctatccctcccccctccccccaccccaccacagtccccaaagtgtgatattccccttcctatgtccatgtgatctcatt gttcaattcccacctatgagtgagaatatgcggtgtttggttttttgttcttgcgatagtttactgagaatgatggtttc caatttcatccatgtccctacaaaggacatgaacatagcaaagacttggaaccaacccaaatgtccaacaatgatagact ggattaagaaaatgtggcacatatacaccatggtaaatttctttatcattcgcactctcctttctctattattgttattg taactgaaccgcagattagtcactcattgcttgcagaatccaattaacaagagcgaggtcagatataaagaaaatgattt attccaaacctccttcagggaagaggtgcagcctcctgcctctaaatgcactgcttcgccaggcgtggtggctcacacct gtaatcccagcactttgggagaccgaggagggcagatcacttaaggtcaggagttcaagaccggcctggccaatatagtg aaacccctgcctctactaaaaatacaaaaaattagccagacgtggtggcgggtgcttgtaatcccagctactcgggaggc tgaggcaggagaatcgcttgaacctgggaggtggaagttgcagtgagctgacatctagccactgcactccagcctgggtg acagagtgagactctgtctcaaaataaataaataaataaataaataaataaatagtaaatgcactgctttgcttttggag cagaaagcaggcactttgaaaaggcaggggaggaagtgagcaagggcagggggtctgcacactggcatggtgcctgatct atccaggcagttgaattggcactttcataggcagaaataagttgaaaaagtggcctaaaactctctaggtgggagtggat agtgggcatgccttcaacctgcctttctggagggtgagttccatggcaaccccctgaagggtgagagttccatggagatc atgctttggtctgtaaatcagctgttaactctctagaaagttctgtcttggagcatatagttagatgaacttgccctgta aagaatgtctggtgaaggggaagtaaaaggtgagatttgcatttctaaagggctaagtagaacgtggggtacaagaggaa aggagaaaagagaaaataatttaaaaaataattgtaacttattcccttttacttagaaaaaagggaatactcagttacat tatcacctcgtttacatcaaaccctcttatggaatcctatggtttgaaaacaaaaaggttgttgaggaccagtgagccca acccctttgctttataaatgaagagcattgcctgccctaagccccagagactctgatgtcgtgggtctggagtgggctcc aacagcggcatgttttgatggtgcttcccagtggcacgccagcgatgagcctttgagtagggaaagtaggagcactcgtg actcccttcacgatcagcacctgtgtgctaataaattcacaaaagccaacatattggagtcactcagggagttttacaaa tagtgaggttaaatccaacctcaaatagttctgattcgatctgcctgcattgctgccctgtggttccccactgtagaagc tccccaggtgattctaagtgtagccaagtctgagaaatactgcctaaagcctgttggactgacagcaagggctgttgtct gagcaagactttgcctggcctggggtggcatgtgcaccaggaagagtctcaactttcataacagaacattccccaagctg gtttttttaaagcatgtgaatctagacttcattggcaataccaaagatctgtatttgaggctccaagtatttcactttca tttttggttttgggttatgttttcacccttcctttccaagtgaaaagtaaacagaagtgggatgtctggcgcccatgctg agcttggcaacttcaaattcaatagagaagaagtctcttgtatagaaaagggcctgtctgagatgtttctcaaataaata tagattttgcttatgtggctaaaggattcttctccccccatttccttatccctgcagtgagccatccttcttaactcttt ccatgaaagcattattcctgaagaactgggaactcatgccagccctgatcaggcaatgataattctgcagagaattagaa tttagatttaaattgtcaactcttatacatcctggcatatggtttaaacacatgtacacacacacaaacacctcctacta tttactgaagagcagatatctgataacttaatctttttggttttgagtcaagacaattcctccttttgaaactgcatacc gctgaatataataaaatgtaattaagattaaaaataagaaactaatgggagaatttcaatattgtctctgttcactttaa aattcctctacttaggtttactgccattaccaaagactattcaaaaatcctttttaggagaatcctaatggtttcctgac atataatcaaataaggactctgttgattggctaactcaatcttcctgtgccaaaaagcagagcccagcagagaagagggc agggacttgaaagtcagactgactcgagttccagccttggggctgtgggagcttgggcaagtgacttaacgtctctggct ctcaggatctaaaaggatttccagtagtaatttggggtgttactgatacaggagctaaaaagaaattatttaggtggtta gtgagggtcagagagtcctcggtaagatttgccttttaacaaaaagcagccccaaaatcatttgtttgctaacaaagaga agcctgtaaaattgagctgcagacatagataagcaagctggaagcttgcacgggtgaatgccggcagctgtgccaatagg aaaaggctatctgggggccaggcatgttcaacatggattctccatcttcccttttctttgtcaaccaagtgtacagtaaa ggaacaggcaacatggcacgggccaggtagagaacccttctgcataataaaagattagggtgagatggccagcttcttcc cgtgctatgtaaatggcatacctggtccaaccagtcttttgggccctgtgtaaatcagacaccgcctcctcaagttagtc tataaaaccccatgcattttaccgtgaaactgggagatccactcggaaccccctcctgcacgagagaccttttctctttt gcctattacacttccgctcttaaactcactgctcatgtgttagcatccttgatttccttggcatgaggcaatgaaccttg tgtattaccccatacaaatgatgctgcttcattactaatagcaacctgacagggttgtgttggggtataaattatctaga ccagggagatccaatataatttttttgtaatgacgggaatgctttgtatctgcatcatccaaaatggtagccaccaggcc agggtgaaatgtggccagtgtgactgaggaactgaatgttttccatgatttaatttaaatgtggccaatggctactgtag gagacagtgtgagtctggcatattataaataataaatattaatataatttgaactttggcatcagtgtttcctagatttg aattactatgcaagttgcttactgtttccaagcctcagctttctaatctgtaattggggctaataatagtatctgcctta caggtttgttcagaggataaatgagaaattgcatgttgagggcttaacacagtgcctggcacataaaagctctggtaaca gttagccactttaataatttgctaataatggctatttcttcttcagattaggatgtgctcccccaaacagtgcacttaga catagcgggcaatccagctcactctctgcagtgagagagaagcactggccgaccagagtcSgccaggggctcatgggtat gaaatcaacagcatgattttgtaagtaatggatggaaagggcctcacaactttatggcactgtgttcaatttgcttggtc ttctgtagctccttttgaaagccttttagggtggattaacctgctaccaataattctggtcagatgtagactccatagct caaagcaaactgagagagtgagggcagcaggccaattccccaccccttccttctggactctgacagaagcttacactcaa ggaagagcaagtaggaattaacgtgttaagagctaggtaagcaaaacccaatgagaagttctggcaaagccccatgggca ggggtggcttaggcacaggaaacaagtaggatttcataccacgcgcctcagtctacttccggggccctcatcctcagctg tgcctatgcaaaggagagcaaccaataaaccccaccgccactctcctactgtggaggccagggatggccaggggtaagag agggatgggaagtgtttcctccagccgtcctctgagaaggagaggaaactgggcagagcttctgtcctccttcaagcaga aacagaaacaaaagaaacccctaagggggttcttacttcccctctagttcagttgtgcactaaccatctgcagctcaaca ttcagcattcattcattgattcagcaaacattgaaggagggccagctatgtgccagatgccaactcatgccatgaaagag agtccctgtccttatgaaattcactatttagagagaaaagcaagcaaaaaggcaaagtttgaaaagtactgttgaagtgg catcattgtctggggtgaatacctgaggtttgtggtctcacgccaagggaatcaaggactcaggcacacaagaagtgagt ttaagagcagaggtttaataggcaaaagaaagagaaaaaagaatagctctcttgcctgcacagagagaggggcacctgag tggatcttcctgttttgtggtgaaatgcaaggcattttatagacgagcttgaggaagtggtgtctgatttacttaggacc cgagagattggtcagaccaggtgtgatgtttacatagcatacaaagaagctggccatcccatcctaatcttttattacgc agacggggtctatacctggctggtgccatgttgtctgttccttactgtacacgtggttgacaaagaaaagggaagatgaa gaatccatgttgaacatgcctggcccccagatagtcttttcctattggcacagctgccggcattcactcttgcaagcttc cagattgcttatctatgtctgcagcccaattttacaggttgctctttgctagaaaagaaatgatttgggggctgcttttc attaaaaggaaaaccttaccaaggttaaaaagaaaaaaatttctttttaatgcctatgttactgtgaacagtgtcgggat aaggctctgagagccagatgaggatgagttatccaatccaaggatgggggtctggaggaaaaaatcctagagagcattgc tgcagttgaataaggattagttagaagctactgagtggagcataggagtaggaactcttatgcaaatgtgcagaggtgaa ataaagcaaggtatagtccaggtgcctaaagtagcacagctgacttgagatagatgatagataggtagatagatggatag ggtacatagatgatagatagatagatagatagatagatagatagatagatagatagacagacagacagacactggtgtga gtgtgggtgtgtgtgtctggctgcgtgcatgcattcctcctgcaggagatcaggagcagtgggcagtatggagtgacaag aagattgggaggtactccttctagccctcccctctgctctgccctccactggagcagaagcaaagcatatggtgaagggg aacaaggagtctccccagcacagtacccgagtgcattagctatttatcactccacagtccccattcacgtgttaattcag catttattgaatgcttactgtttgcaatgtctatgtcaagctgtcaagtgtagtttttattctacaggccacaggcaccc cctaactgtgttaaacaagatggtagtattgagacaggaataataagggtggtcacaggagaatggaagattccaggcag cagtttgactagtaaaaaaggaaactgttgaaatagctgcataatccaggggtcaataagaacctgagaaccagggtgtg agccaaggctggttaaaagcaactggatccaatatggtgctgagtttctcctaggttttgcctggaacctcattatatgc tcaataacataccaaatcacacacccaccagggccattccatttcctggaacactcatgtttggtgtaaaaatgggtggc accacagctctgagaaatctttacctttttcaggaaacttcatgaatattccatcctttggttaaagaaacccataatgt agaagccccaaaccctactgggcgcaactctctctctcttgagtatgcctgcacttccctttattatttatttatttatt tattatttatttatttattttttagatggagtctggctctgtcacccaggctggagtgcagtggcgcagtctcagctcac tgcaagctctgcctccagggttcaggccattctcctgcctcagcctcctgagcagcagggactacaggcgcccaccacaa cgcctagctaattttttgtattttcagtagagatggggtttcaccatattttattttatttttgagacagggtctcactt tgttggctcgctgcaacctctgcctcccaggctcaagcaatcctccaacctcagccccccaagtagctgggaggacagac gtgcaccaccacacctggctaatattttgtatttttttttgtagagacagggtcttgccatgttccccaggctggtcttg aactcctggactcaggtgatcagcctgcctccaccttccaaagtgctaggattacaggaatgagccaccccacccgacca cactcccatttcttgagtgtgtgcattttgctctgcaataaatctctctactttcacttttctctgactcgtccttgaat tccttcttgtgacagcgtcaacagcctggacaccaggtgcagtcaacgtctcaccagtgtttagggacctcccctaatcc actggtatcagcatgatcagacttgctttttcagaaaaagccttctgtccatagaccaaagggaagtgactcagagaagg ggcaggaggaatcacaagctccctgcctgaccaggcctggactatggcagagacagtgagatggtgagaaagcaagggta gacagccagccaaatccagaatatagaaagttctacaggaaaaggtggggccaaggtgggacagggggaaaggaattgtt gcacattaacagtgcaatgcagagcactggtcttgtttatgtccaggttagaacaaaccaatgagaaagcacatctttga gacaactggagaaatttgaacactgactagatataatattatgttaattatgctttaatttggggtacaataatgctttt gtagctatttctaaagagtccttatctcttaaggatacactctaaaatactagtggattaagttatatgatgtttagact ctttttaaaataatccagtggggtgagaggcagagggaagggagaggagcatagaggaaacagtgttggccatatgtttg taattgttaaaactgagtgatgggaatatggagatttaacatattaatactattttctgcccatgtaatatttgaatatt ttcataataaaattgagagagagataaagaaagaaaagagaaaagaagagaagagagaagagataagggaagtggaggaa aaagagctttcttcaaggaccattgtggtggacacaaatgaaagatacccccttcctactatgaattctaggtgtgtact acccaagatgagtcaatcggatcctagcttccagaaatcgtgagcatgatgcagccctacagacgcagtgccctggaaag gagacccatgaccatccaaggaagatgtcccatcacagaactgccctgggtcatgtgttttccaagtccacatgtccggt agttccttctttcctatgaccaatgccaccagtcttccagcactgtcctttattgctaggcaaacctgagccatcctctt cttcttgcaacttgtgcctgaagtaacatggacacaaagtccccacttttcccacattctcagaatgaagtagttctccc tccacactttaggtgctagaggcaagtggattgcttgagctcaagagttcaagaccagcctgagcaacatggcaaaaccc cgtctctacaaaaaatacaaaaattaactgggggtggtggtgtgcacctgcagtcccagctactcaggaggcagagaagg aggatttcttgagccctgaaggtggttgtgttacgtgcattcatgttaagagaccaccaaacaggctttgtgtgagcaat taagctttttaatcatgtgggtgcaggcagactgagtctgaaaaaagagtcagcaaagggagatagggatggggcggttt tataggatttgtgtaggtagtggaaaattacagttaaagggggttgtcctcttgcgggtacaggcgggggtcacaaggtg ctcagtggggagctcctgagatttattgtccaggagaaggaatgtcacaaggtcaactgatcagttagggtggggcagga acaaattacaatggtggaatgtcatcagttaaggcaggaactgggtattttcacttctttgtggttcttcagttgcttca ggccatctggatgtataagcgcaggtcacaggggatatgatggcttagctcgggctcagaggcctgacattcctgtcttc ttatattaataagaaaaacaaaacaaaatagtgatgaaatgttggggcagcgaaaatttttgggggtggtatggagagat aatgggtgatgtttctcagggctgcttcaagcaggattaggggtgacacaggaacctagagagtgagagagattaaactg aagaaagattttgtggtaaggggtgatattgtggggttgttagaaagagcaattctcatatagaatgattggtaatggcc tggatgcagttttgtatgaattgagaaactaaacggaagacacaaggtctgaataagagaaggagaaaaacaggcattaa aggactaagaactgggaggacccaggacatccaattagagagtgcccaagggggttcagcataattatttgcttggttgg tgagtttttggtctccatccttgagttttttttatgttgtcatatgccaggccagattgatttaggtaaaaacaacactc ttcatttaaaaatatacagagttctcctttctcagcagtgagtaagtcaaggcctcagcagttttggaggaaagagaaat gcaaaggaagcaattgtttgttaagaaggattagaaatggctaggagagagtgagtgagattgatagtgtggtggagata gctgaggagaggtagagggtggcataagaatgggaacgagaataagagtgagtataaaagtaaagaatagaacttcatca gggtgaaagtattggagggtgccctgtcagcaaagatcatctgtccactccaagagggagtcaagagtggcggattgggg atagtaccaggagatatccactatgatggtttggaggaaaagtgtaaactggcagtgtaaacaggggcagggcatttatg agtcattgagaatggtgaataggagtatgactagacagaagatagtggagatgacaaattttgggggcacagtccaaata gtgggggtgactgcgtagagctctgttgcaaaaagtagggtaaggataaatagacttaatagaatgaagagatgtattag gctcataagggttattattgttcttcagaaatgcgagtgagtttaagggaagtaggggtgagtacttgcgacttccagaa ggaagaggagagatcaggctggctgtctgatgggcacagctttattctggaacagtgaatccaatggggagggtcgtgca gacggatggcagttggggtgctataaatgaccaggtagggtccagtccatcaaagctgtagagtgtgaggggtcagactt gacaaggactgattgcccagctaaggtatcttcacatggctgggagtttggaggaggcaagagaagattagcagcctggc gaatttcctgtctagcctgctggaggactggaagataaaggcaacaggtcgtgggcctggatcctgtgtgaggactctag cagcacagccttgtatttcagctgtgtgtaaggaaaaaggatgggacgagtcggggagtgctagtgtgggagctgtctcc aggtcctttttgagagagtgaaaggaagaatggggaaaagacttatggtctatgggattagttaaattaccctttgtgag ctagtaaagtggtttgattaggatagcaaagcccggtatccaaagttggaaatatccaacaatgcctaagaaggaaggga gttgttgtttggtggtgggggttggggtctgggagattaactgaacagagtctgcaggaagggtatgtgtatgttgatgg agcattataccaagataggtaatgctaggggaagaaatttgtgcctcagagggcaatactttgtacccctttgagtaaag atgttgaagaagcaggctagtgtcctgctgggaagattggtaagaggggctgcaaagaagaagatcatcaacatattgaa taaggtgggaggtagatgggtgaaaagaaagcagatcatgagaaagggcctggccaaagtaatgtgggctgtccctgaag ccttggggtagaaaaatccaggtgagttgttgggactggtgggtgtcagagtcagtccaagtaaggcaaaaagaggctgg gaggagggatgcaaggggatagtaaagaaggcatctttgaggtcgataacagaatagagttgtggaagggtgtattgaag ataggagggtgtacgggtttggcactataggatggatgggaaggacgatttgatcaacaagacgaagatcctgaacaaac ctgtaagacttgtccggtttctggacgggtaggataggggagttgtaaggagaatttgtaggctttaagaggccatgttg aaacaggcaggtgataacaggctttaacccttttaaagcctgctgtgggatgggatattggcattgagcggggtaagggt gattacattttaatgggatgataaggggtgcatgatcggttgccaaggtaggagtagaggtttcttatacttgtggatta aggtggggagatacaaggggaggatgtgaaacaggtcttgagttgggtaaaagtgcagcaaagagatgtggctgcagccc aggaatactcagggaagcagataatttggttaaaatgtctcagcctattaaggaagctggacaggtggggataactaaaa aagtgcataaaagaatgttgtccaagttggcaccagagtgggggagttttaagcggtttagaagcctcgccgacaatacc cacaacagttatggaggcaagggaaacaggcccttgaaaagaaagtaatgtggagtgggtagcctccgtattgattaaga aggggacagacttaccctccactgtaagagttacccaaagcatctgtgatggtccaggaggcttctgaggtgatcaggca gtgtcagtcttcagctgctaagctgagaagatctgggaaggagtcagtcagagagccttgggccagagttccaggggctc tgggagtggttgccaggcaagttgaacagtctgatttccagtggggtctcgcacagatgggacattccttggcccagtgg ccagatttccggcacttgaaggaagatcctgggggaggaggtcctggagaaatgcctggcccctgcagtttaggtgtttt gaagttcttgtgtgctggagatgtggctggggtttctcttacagcggaggcaagtaattgcaactcagaaatatgttgtc acttggctgcctcttttcta attgtacaccttaaggcgagggtaattaaatcctgttgtggggtttgagggctggaat ctaatttttggagctttttctaatgtcaggagcagattgggtaataaaatgcatattgagaataagacggccttctggca cctctgggtctagagaggtaaagtgtctaagggttgttgccaaacaggccatggactcagctgggttttcatatttgatg aaaaagagcctaaacgctaactgatttgggagaggtcagctaaagaaaaaggagcattaaccttgactatgcctttagct ctagccacctctctaagaggaaattgttgggccggtgggggagggctagttgtggaacgaaactgtaagccagaccaggt gtgaggagagaaggtgaccaaaggtttatagggtaggggagcagaggctggggaagaattgggacctggctaggcctagc gaggaacagcctggggaggaggggagaaatcagatgggtccgtagaaaaggaggattcaaaggactcagagcttggggtg gagactgaaggaacagacaggagagaaagaggaaagatttgggatgagtcacattgggagcagagactagagagggactg atgtgtaaagaatgcctggacgtcaggcacctcagaccatttgcccattttacgacaaaaattatctagatcttgtagga tggataaatcgaaagtgtcattctctggccacttggaactattgtcaagtttgtattggggccaagcagtattacagaag aaaataagatgtttaggtttttaaaagagtgcataaaagaatgttgtccaagtccatgcccttcttaatcaatatgggag ctacccactccacattaccttcttttcaagggcctgtttcccttgcctccataactgttgtgggtattgatggccaggct tataagccccttaaaattaccccactctggtgccaacttggagaggtcaggtgttagtcaaaggtgttttaagttttaag aacacaggctaagggagaagaagggggaatgaagcgtggaaggttgcccatagtgaaagaggtaagtttaaagagaaagg tagagacatggagaaggggggaggtgagcagccctgggctgtcatgtgggttagcagccaaagctggtgtcccagcaatt gacttaccaccaagggaatgtgggtgaatgaccaaggcaggcatccccccggtgatcagacaccaaatggaatgtgggtg aaagatcaaggtaggtgtccccatgatgatcagacaccaaaggaaggctgtcttcccaaatccatgatccatgttggagt ttttgagttcatggataaaatgtgtctcctttgtctctactagagaggaaaaagaactggaatttgaaggacagggagat tgaagggtagggagagaggctgaagaagagagtgaggagaccgcttacccggtttgaaattggtgagatgttccttgggc tggtctgaggacctgaggtcgtaggtggatcttctcatggagtgagggtgaggagaggggaccaatctcccgaaggagtc accctgtccggggtcttcggcaccaaatgttatgcgcatccatatgaagagaccaccaaacaggctttgtgtgagcaata aagctttttaatcatgtgggtgcaggcagactgagtctgaaaaaggagtcagcaatgggagttagggttggggtggttct ataggatttgggtaggtaatggaaaattacagttaaagggggttgtcctcttgcaggcaagggcaggggtcacaaggtgc tcggtggggagttcctgagactcactgtccagaaggaatgtcacaaggtcaattgatcagttggggtggggcaggaacaa attacaatggtggaatgtcatcagttaaggcaggagcggcctattttcacttcttttgtggttcttcagttgcttcaggc aatctggatgtatatgtgcaggtcacagaggatatgatggcttagcttggactcagaggcctgacaggttgctgcagtga gccaagatcacactactgcactcctgcctgggcaacagagccacaaaaaaaaaaaaaaagaaaagaaaagaaaaaaaaag aagaagaaaaaaaaattttttttccaccaagaatttagtaaaaaattatagggaaaagtgtcactaattcaagggaattg cactgaaaattattcattcattcaacagatatttattgagaagcaagtatgctggtgctagggttacaacagcgcacaaa ttcttgtattcaaggaatgaggtaagagtatgcagataggagccagagaggtcaagaggcaattgcaacatagagtgaca cgtgctccagaacacataggagggcttccaggccccatgctgggctatcagagctggcttcctgcaggtggtgtggctca gctaaaacctgagaaccaagaatgagccttctgatatctcagggttaaatcggcacaaatgaaaccattttataaccaaa caacattttccctcctgaactgcactttttctagaacccatttaatccttcctaacatgttcaatccagccccgtgattt ttcagtcaaatgcaagatgcgtaggattccttttctgttcagtgctccccagccaatctttttcccttctcccaccccac agttactaattccagcgtttcagttctcagcagaggatgacagttccaccaggagacatcagtgttatctggagacattt tagttgtcccagctgagggcacagtgctgctggcatctagtgggtgaaggtcaggaatgcacctcaacatcctggaacac tcaggacaatccccagcaacaaaaacctacccatccagaacatcaacagggctgtggctgaggagccctgctctagtgct tcctccttactgtatcctcatcaaggagggctctggggcatgtcaggggctgctacaggctcctggcagatttcggcgac ttactccagacttgtggaacattcaggattcttagcatggccacaggagagtcaggctgtccacaagcactctctctttc ttcacccactcattcctgtcactctaccatttccactgccttcccaaatgcccatcgtgagtcccaccaggggccagaac accactctctcaagcctccccagtggcgcgtgcacacctggagaacatgtctcacatcccccagccagcgagacgtcctg agattccagcacttctcagtgtctttcccagcttgtttgtatctggaatggggtggggtctctcacacaggagaaattac aaggaaaagtgtacgtgacaggaatggaggaatttctgtggaaacggtgtgtgagaaaatgtaggaagaaagaaacttca ggaaatggtaagtggcatcttgagagcagaaagtgagaagggagcagaaagaaatggggctggaacctgggaaggagagg acaggtggggatggccttgcacaccgtgggcactgaggagtgtgggcccatggcatgggtggagaggagtttcaagatag ggagtagattcctattttgaacttcggattgcccctggcgatgtggagactgtattggaagaaggcaagaatggaggaga gcccctaggtggaggtttggcaatgctctctccagaatatagcagaggcctcttccaaggtaggaaagccctgactggag agaagttaatggctctgagggctcaagggaggacttggattatcaggacttttagggaggcatatgatcaaggcttgggt cttggcccattgaaatggggagcactggttttaggatgtgggtcaattagtttggttttcaggacaggctgagttggata tcctgggggacctccaggtggcagtgtcaggggaagctggatgtgctgacactgaactcagcagagtgactgagtagaga tcgacatctggggtcacaggcagtggatgccgtaggggtggactcaatagctcaagcagaacccggaggaatgcaggcag caaagggagccctaaagaacagtgaggagatgtgccaagaaagagccaaatccgggggattggctgtgggagagagggct gtgggagtaagaggaagtgtcagcaacgtcaaatgttgcagagacatagagtaaggtaagagtggaaaaaacatccatgg aaccctgtgatgcaatcggaatgcagaaagactttgtaactcctgcctggtctcctcctctgcccactcatggcaaagga at caaagtaatgttccctccttccgcctagaaaagcacaacttctgcccccaagccctgggctctcctgagaggacagg accagcctctgaagttgaaggtcctggttctgcccccaagccctgggctctcctgagaggacaggaccagcctctgaagt tgaaggtcctggtttaccagatagggaaggggccctttccaagaccctttccagaaggtgtggctgagatgggaaccgtg gactctgtgcagatgtaggagctggctccagtcaagtgctaggaggttgtgggtcctgggaaggaagaggctctggagcc tctgtggagactctgggactgtccttgggggagacgtgagcaggaagaagcagggccttcacagtccccagcttaggggc ctcaccacccagactgaagaccaggaccaaaccctttcctgcacagttacaatgtgtcatttaattttactaaagggaat attttttaaatgaggatgctactttgtgtattaatttttacctctattcataaaagaaacgtttcttatctatttaagat gattcatatcagaccagtgtctgcccaactcgactgaccctgtgaaaactgggcacttcacactccaatgatgatggatg agtccccagcagcatagtttaagggagtgagtgggcagtgtggcctcctgtgcacgtgacttcctccttcagtgtgccca catgtgggttccacggtcttgtgacattgtggctttagaaatttctgtttccattttctatcattcagagtaaatgaaat ttgcaggaaattcagaaccttccacctgtacagtggatactgtgagactctgcccagatgccctcttcaagccaatgcat ctctccatgctcccactcccatagatgggaacagaggtgctggaactcagatctactcccctttctgggaactggagctg cctgcccaggcaatgcccccttcccagggatggctgagccaatgactggctaatgttggattgcagaggcctagcgccct cccctcaattcctaattccttgtaggaataactgaggcctcctctgtgaccacgtgggcagcttctccctctgcctggtc ctgtcttgttctctcctttccaattgtgtctcctggaagccctccccacaagtctgctgcatacaactctccttctcaga gagcctgagccctggattcccaggaatccagcctaaaatagtctggcatttggtttcaattttctctttcactaagactc agtcacaggtgctaataaataataaaatgtcaccaccttgaattctatcactctctcttttcttgccccatctctgacaa gtaggtggtccctcaagaacctgaaaagcagacattaggaggaaaggaggagtgggggcaagaggcccacacctcacctg gccggctcccatccatgcgcccttgactgaggtaacacctaccctgggaatccttcccctgcctctcgtgagccaggccg ggtgctcttgggacagctcccactgctcctgtgtgctcccccagcttggcacatgactccctgaattatagtcagttccg tacctgaatctccctctagaatgccagtgccacgaggacagaggacggttccactttgttcactattttctccccagggt ctggcaaagttcctgggacttgggagaggtgtccttcaggagcttggcagaagccaaacggcacacttaagtagggcaac tgaggtgagtttaatgaaggattctatacaaaaatttggacaaggtatagggaggccacaatacacagtgcagtgcctgg tgccagtgagagcagggcactattcccactgcaaggccagacagggcaaggggagggagctgcctgacaagagctgccct tacgtcaagggacacatcagcccactagaccccatcaggagggagccagggcctgactcccctgaccttgctctccaatc ttctgcctaaaattccccatcagccaaacacaactgaaaactgaaagacaggggagcctgctgttaataaggtgagcttc ccccagaataaagctgggtagagagtggagaatggatatggaagggcaaaaggaagatttataagacagtgggcactaaa tatctatgagatgaataaaggaaccacattttacaacaaacggtcattgaaacgctactcaatggaaagagatcatttcg gtcactgtctggtgcagacaaatcaaagcccacatgcatcaaaaaggccatgtccgtgtaactccgacacggggcagaca gcaaggctgaagcctatggggtatgtggagccggaactgagagatcctgatgtaaatctagcacttgggaaaagggggac tagaagaaattcacccacaggcagaggaaaacacaaacacttatctatttttgcctaggctttaagtggtatgggaaaaa tctctgagactacaaatcctgtgcttcatgcacaggtttataataccctcaaaatggaagaccccaaaaccaggcgcgga aaattcatatcaggccattgatgccctcaatgttcccggctgaaacaaactcaaaactcctctggaaaggagtgctccca cttcaagccatgaaaagctactgcagagaaaataatccccagtcaagacacactcacattgaaactgcaaggcacacaag gaaatggatcaccttgagtgatagctggcagagctaataaacctctgtatacctctaagaagctccacgcactagtataa cccttaaagatttgatgaaatcattactttattaaaattgtttttataaaaaatcaaaatccaaaaaaagcaacaaattt tataccagagccaattcggtatatacaagggtgtcttactcttttggaatttgtcttattgtcctaactcagcacattgt cctggtctatgaaaagtcctagaaacccttctaccctctgtaatgtaggagctttaactcaatagggttttttaaattct tttttcttgtctttttttcttttttaattttttccattttttcaagtcaaactgaagaaatatttttcttttctttctag gaatgcatattcaccccccaaggccacttgtctcctgattggagagtattagacaattctcaggatttctttattttcct tctttattccataggattgggaaacccagtaggattgggtttaggcatatctctaaagcaccatgtttcaacgttttgat gtaagattgtgccctatttcttgttcagttgctgccagcagatgttatagttttaaaactagtttttggtcattgagata ttagaggagggaagagtctgctatcctgctttactcatcttcatctacactacactgtcatcttcactgcaaagtcctgt attaatgtttttagattctataacattttaacaggtgtcaaaaaatcttaagcaccacttcagcttgggaatctctaaat gtaatggtgtttgtgggctggactgatgtctgcgtcttgttgttgttattgtctgtagtaatggagagccgggagatcct ggacacttcctgttcatgggcacttgatgcattagctgccccagcagctgattacatttaaacaaggatgtgtgggtgaa cccagggagaccaatctcagtggaatggtgggggcagaagccaggctgcagggtgtagagtagggaatgagcagtgatga agtagaaacagagtttggacaactagtgaaactgcctggaagagggggagaagagacagtaaatggtctgaccaatgttt gaggtcaaagtgggtttgtaatctttatttaagggacagatctgagcatttaaaaattctgaataatctaatagagagga aaaagttgggactcaaagaaaatgtgggaaaaaatgatgaaggttaaacggaatgagatccagagtgcagggggagagat tagcctttggtgttagaggagcaactctgtccatggagagaggaaaaatgtagacataccacagttgcatttgaagttgg ggcctgaggagttgaggagttctgagaaaagcagaagatgagatcatttcctgagagtaaatgggagtcattagaacggg ggtgaagagactggaagctttaggtagcttgaaatagttgatggaaaaattggataaagtgacaatttgtcacactcaga acagctatcagggaatctagaagaatctctggaagctagttgaagatcttaaattaccaatgtatcttgtccacatagct aagcggttttacttatttttatttttttgaaacagggtctcactctgtcacacaggctggagtgtagtagtagtagcaca atcacagctcaatgcaatctctgcctcccgggctcaagcaatcctcccaccccagcctcccgggcctgggactacagaca cacaccaccactcccagctatattttgtacatttgtagagacagggtctcgccatgttgcccaagctggtcttgaactcc tgggctcaagtaatctgcccacctcggcctcccaaagtgctgggattacaagcttgagcccggctgctaagtggttttaa acagctgttctcggaaacacacactcaaagaaaaaatgtagaggataatttatctaaggctggggcttcaagagaggtca gggtgttgacaagagaatgactaagtggcagactactggatctcagctagataaagagggatgtgatcgtgggaggggct gatagtcagaggctggaaggcttgatgaacaacacatattacacaaagaataaatggagtgagagaaaccaaaggagtaa aagttgtcatcagaaaagtgagaaattttattgtgagaattcagtggtaaatcaatgttaacaaacctcagctgggcact agtggagtgaaaccgaaggccagggagttgagttaatgagctgagacttgggcaccagatgggggtccacatggacaact aagccaccaggatgatgtgggaaactggggtgaatagaagccccttatccatgtgcacaagtcttgaataaaataggggc aaccaggcagtcagtggatgatagcagtgaggtggagcagagagcaatgtagttggagaagtggagcccacagcagtctc ctttatatctagaagggaattaatagccaaaaaatggcaccgaggccaaggatgtcaccttctgactcccaaatctgaga cagatgtgagagggaaggagtatcctcaagggacaggagatggtgcgaatgtttttggcataaatcaaagatgtcaggga aattgtcagaattcaggttccagagacacagaggaaaagcgtgggagaaagtggaatattgggaggtgagattagggcag aggaagcacaaatcaaagaacgaggaatagaaaaagtcatatgagctgaggagttggccaaacatgacagaatgggaata tgatggaattaagtggctttatgtgttccaaaaggattggtccacgcaggccacaggaaaatgggaggtaagaagaaagg gatcgaaatgctgcaaagtgtattacttcatggtaagcaaaggactcaagactctagaaaatgatgcccttccttccaag actatgttagtccaaatctttcaagatacagaacccaaggtggggtctggcatacaagaagtataatagaggaaatgtct gtgacatttgcaggactgcaaagggagccaggagaagctgggaaagccatgagatcacaagcaggtctgactccaagtga aggagatggggaatgacgcaaggtttggctgaagcatgtgccaaaggcacccatcagaggagtccctctccaagggatgg gcctatcatagtgtccctaatagtgtcatggagtgggagcagcccacggagggcacagccttggcatgaacgcagacatg ggtctcagagtgcagcagctgggcccctcagtcaattaggctccctcagagctggggcaggaggtgcactagaccacaca gtaatatttatttattattaatttaattaataatattaatttattaatttaattaataatatatttatttatttattatt actagaccacacagtagtatttgtatgtctaaggaagcatttctcagaatatactcactgaacttttagcctataagtac ctgtatgaaaattttaaaaggggtttcatgatcaaaacattttgggaaacactccataccctttcttcctcatgaaggat cataatgcctattagtatatgaagggctctgagaagtcctgtagtaaagaaacttgctttagttttttagtccagcaatt tttcaaacttaaatgagcaatagcctcccatccttttttttacactttttagcatactgcggaataaactcaacatgcat tgagaaagactgctttagggaatagtcaacactatttcactcccagtaagtacatataaaatctgtatttccagggtgga ttatcaacacagctgtattttagaaatattatctgccctcccaggtatcacagctactaattattgggtactgaggtgga attttagggatcagccaattatgggaaagaaaatctgggggcaggataagatggtctccgaagccttaaaattatatgcc attatttacctctttgatctactactcaatatcaaacaactaattcagaagaaaattgattgttttctaaaagtagtttt tctacatttcccattaagaagcagtggtatttaaaacttataatggctattatgtgagattatcactatcatagtttttc tctatacaaattttctgtaacattttatttgctaataaaaattagatagatggattgactaattgataatctaagaaaga ttat tttgaagaagccatagtaagggacagattaaattatcatcagtctaaacattctaatacctatttctcttttttt gaaattttccaaatttgttattatgcatttaaacaataattttttgaacttttattttaggttctggggtacatgtgaaa gcttgttacataggtaaccttttgtcatgagggtttgttgtacaaattatttcatcactcagctatcaagcccagtactc aataggtatcttttctgctcctctccctcctcccaccctccagtctcaagtagacctcggtgtctgttgttcccttcttt gagttcatgtgttctcatcatttagctcccacttataagtgagaatacaaggtatttggttttctgttcctgtgttagtt tgctaagggtaatagcctccagctccattcgtgtttccacaaaaaaacatgatctcgttcttttcatggctgcatagtat tccatggtgtatatgtaccacactttctttatctaatctgtcattgatgggcatttaggtttattccatgtctttgctac tgtgaatagtgctgcaatgaacattcacatgcgtgtgtcttcatggtagaatgatttatattcctctgggtgtataccca gtaatgggatttctgtttttagctctttgatctaatacctatttctcaagatcaagttagatctctaaaaaaggcatcat cctagcatttccccatcccttccctgaactaaatttaatgttgtgtgtatcaatcagcatacagtcaagacagaaaccac acatgaacattaaatataatgagttattaacttataaaagggtatgaactactaaagggggtaaggagaatgctgaagaa tgcaggaatggcagatgtagagagcagccataacctctaagctaaggcacagcagccaaggaaggggcgaactcaaaaaa tgccctccctccccagctgatccacccttgttggagggggtgtggctgcaacccaatggatgcccaagaagtttgcagag ttgtggcaggttggggctgctgagcaggaaactgcccgaaggggtaccagtgagattcccaagaatgtgggcatgcctct ggcgaggaagacgctcttggagtgccagcaaaatttactaggaagctacccagtagggtgccagcaaaagtcagcaggaa gccactgtcgtggtgtcggcaaaattcactgaggagtgggcactgcagggtctccacccagcactggcaaatcagccaaa agaacaaaaacaaaataaaaacaaatcccagaaccagaaagaaaaaactctgcctcttactgcgaccctcttatgccttc tacagcaactggcaaaggagaaatgtttatggggtccagctctagactcacaaagcagaacacagaagagtgaatgaaga gctgaaaggcgataaatcagtaactggagcctcacatcctttgccttttttattgagggtcaatatattaagaagaatat gtctgcgtcttcggtaaaattattgctaaggttatcacccagtgtgtgttttcaacctccctgatataagaacttagtga caagaaagaatgagacaatgatcatgaactattggacccaaccatttgtggctttagtgcccatcttctcagcaaggctt tctctctctctctctctctctctctctctctctcttttttttttttttttttttttttaagatggagtctcactctgtca cccaggccggagtgcagtggcacaatcttggctcacggcaacctccacctcctgggttcgagtgattctcctgcttcagc ctcccgagtagctgggattacgggcacccatcgccacccctcctggctaatttttgtatttttagtagagatgaagtttt gccatgtcggccaggctgttctcaaactcctgacctcaagtgatccacccacctcagcctcccaaagtgctgggattaca ggcatgagccaccacagccagctctcagcaaggctttttctgactacactatttaaaatgtgatccctgagccaccttgg cctctcttgctgtccttccctgcttcgccttctccatagcacttctctcctactaatctacaatttacttgagctctgtg aaggtcaggatttttgcctattttgtccattggtgcatccccagcacctggaacagagctaggcacaggctaggcactct agaaatacttgctgaataattgaattaagtaaatgagtgatctacacgtagtggggaatgagagtatacagtgatagttc cttcgactaaaactggggtcaaattatagtgataaagaggaactcagaccttcagaggtaagctttgtggaccacttgcc aaggctgcagaatgtgatgtcgtttcacaaacaaggaggccctattatggcttcagatatgagaataataaagagaactt tcctttcgcctcaactgcagccttctaaactcttccttccttcctatgtagaagtttcaaggacctcatggcctgagtgt ggataggcagaatgctgggaatcaggcaaaaataaaataatactgaaagtgaaggtcatgctaatattagtaagccaggg tgatcctgaatttacaaaacatttttctttgggaaatttcacacctcacatgattctgtgtttttacttgggaaatttca catctcacatgactctgtgacatgcggtacatgaggtgcctgactgctgtttttgtcctctactaatgaggaagagtgtg cgtactcccagcgttttgcaagtttcaaagtctgacttgactttccttccttttcctggaactgatccatgagtatcgag agtaaagctgcccgcacctactcattcaagatcctgagtgtcctgcccagctgcaggaggtggagagacccaggaggagg ggccactgctgatcccaggctgtagggggtgggaagagtgtcccagggcaccatgacccccactcactcactcacaggag acccacacaagagaggagagggcacttacagcttaggttcccaccagcaccaactcctctgccatcaaacatcattgtgt ttctctttctgccttgtctgtcggcacacgtggagttaaatttaatgctcaatcacatatttgtctgggctctttctgtg tttatttttctcttaatagttctctctcctcccttcctctccccgcccctcctcctccttcttcttttttttttccagag acagtgtctcgctctgccacccaggccagagtgcagagtggcatgatcatggctcaccgcagcctccaactcctgggctc acgtgaacatcccaccttggcctctggaatgtctgggattacaggcacttgccactgcatctggctaatttttatattgt ttatagatccgggatctcactatgttgcccaggctggcctcaaactcctgggctcaagcgaccctcccacctcatacttc tgagtagctggggctgtaggaatgcgcctcagtgccaggctagtttcttaattttctatttctattttgacaggtacaaa ttttgtattcaatcctacctcagacacatctttggtgggaaaaggatgtcatttaatcaatatataaattctaagcaaat aggtctgatccccaaattaggttagtcacagctgctgagtcgttgacccaagagaagctcatctagattttttcattatt ttcaagttcctcttctcggttcgtccttcttccagaccatgccctccccgtcccactctcttcccacagcctcccctccc cacagcctcctcccaccattccaaatctgggctgttctctcaatttccttctctctggactcaaacctaccctagccccc agcctcagtttggggttaaacttgtcctcctcacattctctcccacccaacttgatgtcgcctctgtgtca caccacgg gattttcctcctctgggttctccttttccgagtggggtcagctcccccatgagtcacagcaccaatcacttctggctgct tgcaaacccctttgctttcctcagtgttgacacccagggcagccctatgctcactgccgctgagaccccacctctgcccc tggccttttcccagctgacatcaccctgtggcttccattttcctaaaattctcttttgaggcctcagtcttaaccaaagc acacagtgcccctcaaaaatgacaataaaaacccaaacacaccgtgactgtcatggcaggttcctggtccccgtattgaa tcagcgggtgggtttctgcgaacactggtgagaggccgcattagagggtcaggaccctcaggtctggactcgtggtcacc acataccttcctccctgctgacagtagctggtacctgttacctactcagagtgtcacatgccacaagccagagcgtcttg gcagttctcagcaccttgacatcacttccttgctaccactcagagcggcagtgacacagttcccttatctcagaaggcca gaagacggctgtcaaaggtcacagggaaatcaaaggcggggtacagggccagagggaggaggaaacaacttcccggttgc tttcagacgcttcagagatcctctggaggcctgggggagcttttgagtactttatttcagttggtccctgagctcggtga gtggggcgggtagagccaccaggggaatcaacagtggtttctcgtgcccctcagggtcaggagcagtctgatcaaaagga gggcatccactgtccggggccattcccacagctcccggatgctgggtctggaggctgcgcccttcccctgcaggagctca gcccagtggtaagtcatctgtgtgtcatctatgtatttaaccccttatggccatgttgatgctgagcatggtttcacttt tgcaaacatttatttatacccttcgagagaaaaacgtctcagctgtcacaggaagctgcttcggggggtgagcaaacttt ttaaaatgcagaaattatgatctacacccgtttcttaaaagtaagccatcgtacttggttctctttaattatatattttc ttacatattgtgttcatgtaggcaagtcctgtttctgctaaaagaaggtaagttctaccaaggcggtgtcatgccagctt tatttcccgtggcacctggcacactgctaagcacttacatgcttaacaactagattgggaatggtgctgctctggggaag tgggcacacgttaaagaaatgtttatttcagtcttctgaaatagggaattactctggctaaaatgtagctccagaaaggg aaagtggggctgtatgaatccaggtccagtttgttgtttcctccaggataaggcagctgtcggaggggaaaatcatctcc catttctccacagggcagtctgaagatggccaattacacgctggcaccagaggatgaatatgatgtcctcatagaaggtg aactggagagcgatgaggcagagcaatgtgacaagtatgacgcccaggcactctcagcccagctggtgccatcactctgc tctgctgtgtttgtgatcggtgtcctggacaatctcctggttgtgcttatcctggtaaaatataaaggactcaaacgcgt ggaaaatatctatcttctaaacttggcagtttctaacttgtgtttcttgcttaccctgcccttctgggctcatgctgggg gcgatcccatgtgtaaaattctcattggactgtacttcgtgggcctgtacagtgagacatttttcaattgccttctgact gtgcaaaggtacctagtgtttttgcacaagggcaactttttctcagccaggaggagggtgccctgtggcatcattacaag tgtcctggcatgggtaacagccattctggccactttgcctgaatacgtggtttataaacctcagatggaagaccagaaat acaagtgtgcatttagcagaactcccttcctgccagctgatgagacattctggaagcattttctgactttaaaaatgaac atttcggttcttgtcctccccctatttatttttacatttctctatgtgcaaatgagaaaaacactaaggttcagggagca gaggtatagccttttcaagcttgtttttgccataatggtagtcttccttctgatgtgggcgccctacaatattgcatttt tcctgtccactttcaaagaacacttctccctgagtgactgcaagagcagctacaatctggacaaaagtgttcacatcact aaactcatcgccaccacccactgctgcatcaaccctctcctgtatgcgtttcttgatgggacatttagcaaatacctctg ccgctgtttccatctgcgtagtaacaccccacttcaacccagggggcagtctgcacaaggcacatcgagggaagaacctg accattccaccgaagtgtaaactagcatccaccaaatgcaagaagaataaacatggattttcatctttctgcattatttc atgtaaattttctacacatttgtatacaaaatcggatacaggaagaaaagggagaggtgagctaacatttgctaagcact gaatttgtctcaggcaccgtgcaaggctctttacaaacgtgagctccttcgcctcctaccacttgtccatagtgtggata ggactagtctcatttctctgagaagaaaactaaggcgcggaaatttgtctaagatcacataactaggaagtggcagaact gattctccagccctggtagcatttgctcagagcctacgcttggtccagaacatcaaactccaaaccctggggacaaacga catgaaataaatgtattttaaaacatctatttaatgtattttaaaataatttgtaagttgattttaaaaccaatttaact acattccaaattatagacagcccatttatatgggagtaacttttcaggctcattgcctcgccggtgatgagaagaactag ctagctggaagctgtgggaaaaagaggtaaggtaacttgttctgtcgaagttctctaaattctcttgcttacttgccaca cccctaggcccccagcttcccctaacccaaggtttctggtattttctcgtactttatcaagactatggaatcttaggaga cttaacaaaagcaaatgagaaattatgtttagaaatgtctaacaaaatgaattctttgtccttttaagtataacacatac ctcaggcctcaccagcacataactacaaaaggttgtcccacttcctttctgtggctgagttagtagaacacaggctccca cctgccacatcagcagaaggtcacctcaacatgtgagctacctccccggagaccccccagatccgtaaggatgatgcatc cttgatcctaaaaacattttcctgttcctggtgttcagaattggactccacactcactggtctctttataatcttgcttc tggccctttgaggcctcaaagctaccagggccttgctgccaggggacaatcaccgctcccggctgagtcctgcagacata gggcctgggctggctgcctcctcctgctggcccagcatcttgcttgcactaaagagagctggaggcttggcactgatgct tgctaaaaacctacccaggccgcccactgctgccgcactgcagggcaccagcccacactcctcccctcctggcatcaggc acacgttcacggcactaaaccttacaggaaagcagtggaaccctgtctttccttcacaggaggcactttccttcctaggc aaaaacgatgatacccatgggcacagcatctcacatagggacacatagagatgtctgactcattaaaacccaagtctctg gccaattaaaaggggtccttaatgtcctactcaacagtggtggaaggaaatttgctctatattgatgaaatgaggtggag aaaatctgattttccaaacatgagaattctccatatgccaccccataaccaaagaccccttatttgtgttagatgaaaca ttcaaagagcctattaggatagcggatgagacccccaagggacatgcttatacaacaataactggctccaaaccacactc catggcagtggctctcaaatgccagctcacatcacaagccctgtgctaaaacacagagttctgggccccatcccggagtt tgtggttcaggaggtctggagtgtgacctcagaatatgcatttctaacaaattccccaggggatgcagatactgctgacc caaggccctccttctgagaaccactgttccagggagaagaaactcagctaagtaagggtttggctttgtgctgaagacaa tgtggaatttagagttggggtgaattattcaggaaagtagagaggtttggagatgtgagggtgggaagcgcagtggaggg aggcagagaggaaatatgaagcagcgtcagttggagagaaattaggaagaggaataaaatgatatatgccagggatttca gttttgctgagcccatgatgacagactcttctctggcaccttatgccactcattgagggcttgtagctggctctgctctt tcagagtcataatagggctatgggtctgacctcaaggtgagctggaatgggcacaagtaatagataaaactgcaagaagt cactcaagggtccttcctagaacaaaggatccctacattccaaaggcgaatgccggtcactatcataaaagaaaagaaag aaagaaactgatggtgacattttaaatggcaatttttctagcttctaaaaggttgtggagcaactggaactttcataccc tgctggtgggaatgtaaaatggtataatcactttggaaaaattggcagtgtcaccaaaagcaaagcctatacctactatc catttcactcctcagtatttacccaagagaaatgagcatgtatgtccatacaaagatttggacccaaatgttcatgacag ccttatttatatagcctcaaactagaaaaagtctgtctatcaacaggtgaatggataaacaaatactggcctgtgtatct aatggaatactgctcatccacaaaaagaaacgagctattgatacacacaggagcatgcacgaaatctcaaaatgctgaat gaaggaggccagattttaattttatttttaattatttatttatttatttatttttgagacagagtctcgctctgtcaccc agcctggaatgcaatggtgtgatcttggctgactgcaacctctgcctcctgagttcaagcaattctcatgcctcagcctc ccaagtagctgtgactacagtcatgcacaagagcaactgactaatttttgtaattttagtagagacggggttttgccatg ttggccagctgctctcacactcctgacctcaggtgatccacctgcctcggcctcctaaagtgctgggattacaggcatga gtcaccgtgcccagccggaagccagatattttttaaaagtacttattttgtgattctatttatataaaattctagaaaat gcaaacaaatccatagcgacagcaaatcagtggttgctggagatgttggaggggagaggagaggaatagattgcaaaggg gaacaaggaaattcggggggacagtggatatgtctgctattttgactgtggtgatggtttcattggtatatacatatgtc aaaaacgtaacaagttgtatacgtgatttattatgtgttgactatacctcaaaaaggctattttttaaaatccccctcag gctccaggcactccattacgttggtgtgacttgtcttggaaatatactttgagcatttgccggaggagatccagtgcctg ggcctctgtttcttctcccaagtagaattggcagctaaaacgggatgcccatgggcacaacttgtcacccccatcaccga acagggagcagaaggaggctgctgggggtgcccccacagggagcacagtctcatcgggaatgacctgccatggcaaataa aatcaccagggcaagtcaagggagagaccagggaagagagtgatccagtctatattaaaaaaggatgagaaaggttgaag aaaaagagaagaagggacagaaattctcttcacacatttgcagaagtaggtccggactctccatccacttctcctcctcc gataggtaggacaggaatctcagaggaaatggcatcatcttcccatgtttacagacacagcaatgaactcaaagaacaat cttatcaggattttccaaatgaaaacatggagcatatagagaataaagatccataaactcgtatggtggctgagactgaa atggttaatgaaaagcaaaagtgtgtgctgaatgacaccagccacaatggcctgaacacttaagtagtgtaatatacttg gaacattgacagctaacaaggtcttcctcccatgtcagaccaagaacacagtttcctaaagataaaaatagcacatgctt ttccacttttccataagtgactgcattagaaaactaacaaaccatgaaaagcaaaatatggctagtctcttcaagaaaaa ctggtgtttctattttgtctgtaaattactttctaatacaaaaaacaattcctgttacattgaggtaattctaactaggg acatatgagagagagattgaaatctcatgagctgtctccttttcatctcaattctgtgtactcgtgggtacaaatggaac tagtttttgtttgtttgtttgttttttgagatggagtcttgcgctgttgcccaggctggagtgcaaaggtgtgatctcgg ctcactgcaacctctgcctcctgggttcaagcaattctcctgcctcagcctcctgaatagctgagattacaggcgcctgc caccatgcctgactaattttttttttgtttgtattttttagtagagacagggtttcaccatgttggtcaggctggtctca aactcctgacctcaggtgatccacccacctcggcctcccaaagtgctgggattacaggcgtgagccactgcacctggccc ggaactagttttaaaacaggaaacagttgatatactgaatggaaaaacaatacaatttgaagttgaaaaaacaaaataag atgcccagttaaatttaaatttcagttaagcagctaatagttatttagtataagtacaacccatatacgacaattgcagt atttgttatttatctgaaattcagacttacctgggcatcctagtatcctgttttttgttttgttttgtttttccctttgt tttcttttttttccccgaaatctgaccaccttaactttaaggtatttattcatttttaaaaactaaatatttttcggcag tcagaactagagcaaagataaatgatcccaggactctgtttagcaggcagtcaggaagtgtgacagtgtggtgggtggca gccccggccaggcctttcctcttccctaaactgccacagcaggactgccacacttgggaatcccagtttccatctgagca gcccctccagagtttggaaggagtcagtgctttagcctgaggagccgtggatggctctaacactttgcttgtcggttgaa taaaaatcaacccaaaggtggcctacactcattgaagtaggaatgccagaacttcagtggtgtcacatagaagaaaatat ctaagtgcttagggagatggcagtgctagtggatctactggatcattaagactcactcacccacccagcgcaggtctaga ggacacacccttgccacactgggaagtgtaaatgagctccagcatctttatttttttttattttttatttgttttattat actttaagttttagggtacacgtgcacaaagtgcaggtttgttacatatgtatacatgtgccatgttggtgtgctgcacc cattaactcgtcatttaacattaggtatatctcctaatgctatccctccccccgcccccggtgtgtgatgtcccccttcc tgtgtccatgtgttcttattgttcaattcccacctatgagtgagaacatggggtgtttggttttttgtccttgtgatagt ttgctgagaatgatggtttccagcttcatccatgtcccgcatctttaaaaaaaaaaaaaaatctctaagtggtggctctt ctctgtagatcaggagctgtagtgagcaatgctacaaaactggagtttctaaatacaggggggatggtgggattctgagg aaggacaggccacgtggtaacacttacaaaagaccaagtgggtgtggttgccactgtggacggtggagccaaagcagtcc tcagaatagtctgacccccagaggtctttggcattggctggttgatcatggtgtccctggaattgaaatagaaggacggt ctactaaatttttacctgatctgtataagcagaagagttctatctctagtgaacagaagtctaactttagtcaccagaac tgagagtcaattcaatcaattcccagatttgacatagtttatagacctagaaccccttgaatgaaaggtaagctggctcc ccttgaggaaggaccctgttacatttccggcattttattctgataatcttttttcccagccttccccaaagcaacttagg gccatttaccagggaaagccatggaggaaaaggaaataattaggctatttggagattccaggacactggctctacgctga caccagttctaagagacccaaaatatctttgtggtctaccagccaaagtagggcttcatagaggtcaggggtcactagag tttgagctcaggtctgtttcactgtgagtctagagggtccctgaacttatcctatagttattcccccagttccagaatgc agaattgagctgagagcagtggctcatgcttgtagtcccaacactctgggaggcgaaggtgagaggatcacttgagccaa gcggtttgagaccagcctgggaaatatagtgagaccccatcttttaaaaagacaaagaaaaataaagaaaattgacatgg aaaaataatataaaatgtgaataatctcacatctactaaagaaattcaatctgtaattagaactcctcccacagagaact ataagcccagtgcccccatcaactggagaaacagaaagaaacaatcttcttaacagaaagcataattggaatagagatac tctgcatcggggaagaatccccatattgattctctgatccatagagtgaaggccaagtggaagcctttggaactccctct acctgccaagatactaaacaaaacaacactgcacgtctggaggaattgtagcaagaacttgaaagatgaaggatgatgat gtccacctctctccattcagctcacctatctggtttgtgcagaagacaaataggtgttggaaaatgacagtggaccagtg taaacttaatcaggcgggggctccagctgcagctgcaggatcaggtgttgtttcatttctgcagctaatcaacccttctc ctggcacctggtgtgcagatggcaatttttcttttctattatctgttagtaaagactatcagaagctgtttattttcagt tggcaaggtcagcaatacactccaagggaagagcagtctgtctcagatcttaccgatgcctggggatagggagggagtgg ccccctcaccgtctccaaggcctagtcctctgctcctgctactggcagcaaatccacgcaggtctgcaacaacctcaatt cctgcctcctcagaagaaagaattcaattgagggacgtaagacagaaggagagactgaggcaagttttagcacaggagta aaagtttatttaaaagctttagaataggaacaaaaggaaggaaagtacacttggaagagggccaagtggacgacttaaaa agcaagtgcgtggtttgaccttttgacttggggttttatacgtcagcatgctttcggggtcttgcgttatttctcccctg gttcttcccttggggtgggctgtcccatgtgcctgcctgagcccactggctcaactcctgagatcttatagggaaactac tgctcaccagtttcgagtgttttctatctattaggagccggcttttccctgttgccgggtgtgaccaattattactttag aaagacagtcaacaaccgccagaccatcacctgatggtcacctgacactcctggtgtgtggggtatggggagccctctcc tgccctgctctttctgactagctacccactataacactcccagagggacctgcacattttgtgctctttgcaagacagtg cctgcccagcacctgtaggcctgctcaccccttcagggtcatgatttttgctttttaccgcaggtacccataagcaaaac atggcattgttcaccatgcttttacat a tcacataattttaagttatttacacaacaatgtaaaaccatggtgaacca tgccacatgttgcttatgggtacctgtggtaaaaatcctgctactagctcattttgcagtgtctataatgacaggtaatg ctccattcactcctttatgacacttgcaaaaactgagaacataacgcctcccagttaagcaggcatctgggcaatgtgag gagaacagaaatagaccacgctgcatttatctctcttgatgacaggcattgagatttccactttttctggtttcttatta tgtctctactgggcattcttacatacatcttgcacgccatggaaagtttctctagggcagtggttcacaaactttttgga tacagaatacttttatgtgcttgaaaactgaggaccccatacagctttagtttatgtgggtgtaaggttctagcccaaac tgaagtccgaagggagttggtgggtgggtgaggggtagctgaaaaaacacccgaggaatcataggcagtttgaacatggc cttatcctctctctgggcacgagccatatgtccagtgtcagcagggtaattataccttttacagacaatagaggctctga agcaatcacgagctcacgtgagtggtcacctaatgcacctcaagtggcatggttcataatgtgcggagtcgtgtgcctac gctccaaacccactgagtcatggtgcaccaaaaagtggcctcagcctgctcctgactaaagcgcagccatcttccttaca ctccacccctaggccaggggcatcctccaggtagggacatgtgcccgtagggtggagccctgaatccataatccacagca acaatacggagagcaacagctcatgactaggattccagctatgctacttatgactatcagggcccagcgtaggccagagc ccagggatgtctaccatctctgcagggggtcatcagtaaggctcttgactaccttaatctcctgtgagaccccttgcagg gctgctgttatgttctgccaattgtcagggataaaggtacaacattgtgttcctaaaagggcacaggtgcctccttaggc agcagttactatgtctaagaccattcggtttcgcaacaccacctttctgatctgatcaacctcatccattaatgggaaga gggccactcaggtgtaattcagagcctgagcagcatgctctgcaagagcagtaacttggcttctacagttgtgacacaca ctccagggctagtgcctgtcaaggggtaaaaccaccagggtgctcattacacttgcaaaaaccgagagtgtagcacctcc cagttatgcaggcatctgggcaatgtgagaacagtggcaggtacatgaggccaccctcaggtataatgtccagtccagtt tgcttataggtaaggccaccctgtgtccccacagacccataaactcccagggggcacacagtccatcgaggccccttggt ggggccgcgtcttccaccatacctttggtgtggtgacatgtattatgcttacacacactgtgacgggtacccatcccaca gtgctattaccccagtgttgctatatgcaccacagtgcctgggccaggggtactgcacgttacctcactagccagcccca cccatcataaatgctatgggccagccagggaatggctgtgctgtgggtcttgtggcatcctttgtccaaaacttgccacg ttgcgttccaggcatcagccatgggaccccaagtctccagccatgtctggttctctgcagatgctgaatgtatgtgctaa ggcaagccatctgcagctgctagaagggcggtgcagatccaacagttggaaacattggtcacttcagtgtaggtgtgggc ccagtccacaatgcagttggagcatgttaacctacagttggaatgacagagtaggcataggtactaacagaggaaaatca catccctcaggtaaaatacaggctaacctttcatccctggataacaatgcagcccccaaggggttctgccctgggcaata gtaccacaccttttcagctccccatggttcctttgggtcctgtattcatgcgaaagtcacaggggagcttgtagtaggcc acacagacagtacatttgaaccctggaggaaagtttcttccctggccgttttcctacaaacagttaacttcggggaccat tcattgaacacccaaagagtgacatacaagtcatactgtaggccctccccacagggagctacgatggacaaccaccagca gccgggggcttggaggggctatggccacagccaggttttctgttcccctgccttcagggacgttggggcaggcaacaaca ggttactgttcatccccatacctggtcagaggcggttacccttggtgtgtatctgcaactgaataggggtggtggcccat gtaacaaagcctccacctgggctgggctgcttttccatggccattcattcaaggtttggagcatcaggtccagcctggaa cttcagccctgcaaagacaggagtgtgacatgcaagtaaaacccattcttcaagagctcgctatatcactcaatcatacc cacagcttgcaagttgtgcggtacatggaatccctactttatgtccattgttgtgcctgttgtccagtaaaatgtgtccc ccatcactctcaatgaccaaagggcaaccatatagagcacataagtgttgcagggtctggatggtgtgctgttggttggc caccctgcaaggataggcaaacaacaggcctgtggctgtgtccacagctgttagcgcatgagtatacccttgtgacttcg gcagcagcccaatgtagtctacttgccacctggtcaagggcacttgccctgttgtcacttgtgtagcactggacagctgc ctccatttagggtatgcctgagcacatgccgggcatttctgacaagcctcccaaatgtcttgcatgggcagagacagacc ccaacatttattgacttgttgcatcagtttaccccctgcatgtcccagtttccggtgtagctacaaggccacatctcatg tagatgccaactctaaccatcggaccttggccaaggcttctgcctcgtcattgctgggggtggccagaggcatatggcct gacaaatgataaatagttacatctttgcaatgacccatttcccagaggtcttgctacatgggttggtggccccaaatggg ttggtggccaactagccaattctgtattttccaagtagttaaacacaaagttaggcctccatagactgcccagctatcgg tacggattaccataggtgtctccgccttgttgatcaccatccatactgctttaaattcagcccattgactactttgtcca ca ctggtttcaaaccatatggttttggtactaagttggactgcaacactggtccaagcaggagtagcacctcgactaga cccatctgtgtgccatgccccatcaggaatagagggatgcccttccttaaatggcagtggctcagggtcaaggggtgcct caggccccatggccttctcttgcattaggactgcaggtcccaagacctcttgcaactctgctgctaatgggcttgtgctc agcgtactctgttgctccaagtaagtgcctcactttgccaaagtggatgtctgcaccatcccagtctggggggtcattac acatgaatgcacccatcccgctgtcaggtaagtcatccacactgtgactgtagcccatcctatcacttctcacaagcctg aagggcagcatatacagctgctagctatttctctatcaaggaataccagagctcagctcctttccatagttgggaccaaa agcctcctggcattctcaggcactctgtgtgctgccacaggcccaaactaaaaccatctgtggtcacatgcatatccagt tcaaatgggcaccccttgtcaaatacccacagggctcgtgcctgctgaatagcccacttggctgccaggaagccagtctc agccacatcagcccaatcccagattgctcccttctttgttaactgatacaatggttttatcatttgagctaaatgaggca ggaatgtccaccaatatcccaggaggctcacaaaagtttgcagctgcctcaccgtggtgggccagggatatgcctaaatt ttgtcaatgatagcctcttgtatggccttcatcttacccgaccagataactcccaagaatttagcaggtaatccaggccc tcggaccttggatttgttgatggcccaactgcatgctgccaaatgttgccacaagaggggtgccactgcttctaaatctg caagagaatcagaggttaacataatatcatcaacgtaatggaacaagtggactccctttggacattttcaggctgttaaa tccatggcaacaagaccatgacatatggtggagctatgcacatagccctgcagcaacactgtgaaagtccattgtcatca aggcaaactgttcctggctctctagagcaaggtcaactgagaagaatgcattggccaagtccaccacatagtggtactgt cctaattccattgtcgagtggttcatcaaatccatgatagatggcacagcttccaagccatgtaaaatatccacctccag aatgtattcaggtatgggagagacatacacagtgtataagcaaggagccaagtggccaatgccaaggtacagagatacag gt tcactttcactgactggcctσcgtaacctttaatatatgcagatttgcccaaaaacttaactgggttcccataaaca aggctacaatctatgccagtatctaccagcaccagcacccactgtacattggtgggggaccagtggattgccaattccac atgtggcctctggtcatctggtgtccccccaagccagacacctttggccagttccctagttgaacagaaaaggctctaca tttccacctggctgcagcaagtagtctctgagctgggtaggaccaggtcacacagcaatgcctttctcccctttgggcat tttccggaattgctgccctgcatacaactgtctccgcaaagttaggagtatttcattgggctgcttatcaattttctctc agtcaaccccagccaaaatcaaatctatccacatctgtgagcgtgtcactcgttggggccccctttttttatgggggagc cccctgtgggtggggtaacttccccttctttatggtgtggaccctccaatccccctgaaggccttctgcttccctgagag ccgccatggcagtggttacttcatgtatgcggtgccctacgtatggggtgaggacagcagctagggagccaaaggggctc aggagcatcaaacccaacatgagatccctcatgtgggaggtgaaacatttatcatctggccctcaggtattcaggacaaa catagcctgccgcatacccatctcccgaatgacttacaccaaattggcatatgactgccatttactcacagttttgggca tttcaccagcattattccacacagttcatatggctgcctgtagccactcagtcagggtgtggtctccttgcgctgccact aaccacctgctcacttgcagccgctgacagagagaggggtgagtcatggtggaggccagcttgtccatctcagaggtgga atgggagataccatctgctcccttgttccacagacgaagcatccaggcaggcaggggttcccctggacactggcaacact gcttgcctaattcctgcaactcagttggggtacaggcaatatacgaaatgtgttgcattatggtggggagtccctgagtc cacccttggagccccagtggctgttcatgatctaccttctgtcagaccaccgggtgagcccgcaacaggggttcttcctc cttggtatgaaactgagtggggatctccagacaagatgatggacccaggcctgcattcatggtagcctctaattcctttt ccaagctctgaagccacacctccaggcatcctgcctgcacctggaggtccccattcatggcagcctctaattattttcca gatcggtgtagccagacctccagtctgcatccctcagggactgggtgtgtacttttcttagcacagttaaaaatgcccat ccaactctgccagcaaaggctctctccttcttggtgctctgcacttccagctgcttcagcgccttctccatgctcatggg ggacccatctactgccacccaggtttccactcaagcccaccctcacagcacggctaccaccgggtaccacaacccatgtt gtggtcacatggccaacctggaatcagcagggaccgaaggctcacttaccttaggatcctgttcgtgatgccaattgtca ggttctagcccaaactaaagtccaaggggagttggtgggtgggtggcaggtaactggaaaaacactcgagtaggcggttt cgacatggctttattctctctctgggtgcaagccatatgtagtgtcagcagggtaattttaccttttacagacaatagtg gctttgagccaagcacgtgctcat tgagtggtcacctaatgcacctcacatggcatggttacataatgtgtggagttgt gtgcctgcctccaaacccactgagtcatgctgcaccagaaggctgcctcggcctactcctgactaaagcacaaccatctc ccttagagtgggctaaatctactgctatttatactattagaaattttaacacagaagttttaaatatttacattgttaat tgattttgaaataataagcccattacaggttaacataattaacatacttttattaaaaatatctgtattttttaaaagaa aaaaaattagcaacaacagtgatccttggaatcgtcccacctcagcctcccaagtagctgagaccacaggcgcacatcac catgcgagctaatttctatattttttggtagagatgggatcttgccatgctggccagggtggtctcgagctcctaagctc aagtgatcctcctgcctcggtctcccaaagtgctgagattacaggtgtgagccaccacttctggccagaagctggattct ctgtcttgttctccatccaatctgttagactgtcaaatgccaaataacctttggaaaattctactcgtaaaataaggaga gagataaataacttctgagtatcatcattaaaatagtttgacctcatggacccactgggtcccatgtggagaatagctct aagctaaagagtagaatggctgggaggggacataaacattcagcccatagctgctgaccacaataacacattttaagtct cttcctctcctgctccttgtgattgcagacagactcaatctgtaggagagctgtagagagaacaagctcaagcccctgat tttgcctacaaagaaagctgagcccagcaaagttaagggacttacccaaggtcacacagccacacagcagagctggggct gagctccaggtgtcctgctacagaggccacttctttctcccactagggactggcctgtgattacttcagaaaacaatggt cagctaactgattctgaacgccctttgctggtaaaagctaatctcctgaggaaaaatgtatgcattggctgggcgcagtg gctcaagcctataattccagcattttgggaggtggagacaggtggatcacttgaggtcaggagtttaagaccagcctggc agtcatggtgaaaccccgtctctactaaaactacaaatattaagctcggcatggtggcaggcacctgtaatcccagctac tggagagactgaggcaggagaatcgcttgaacccaggaggcggaggttgcagtgagccgaggtcgcaccactgcattcca tcctgggcaacagagtgagattctgtctcaaaaaataataatagtaaaataaaaataaataaacaaataagtatgcatca cctcaggtggtcagtcagctttcccaagaccccaaagcacacaatgttctttctggtatgagtgacatggggttcacagc accacaaagtccatgacttttccctcagaagtgaatgcatggctaattattttgtattttttgtagacatggagttttgc catgttgcccacgctgctctcaaattcctggactcaagtaatccacccacctcagcttcccaaggtgctgggattacagg catgagacaccgcatggcctgcacctatagtcccagctatcaggaggctgaggtgggaggatcacctgaaccggggaagt tgaacctgcagtgaactgtgatcgctccggtgcactccatcctgggcaacagagtgagatcctgcctcaaaaaaaaaaaa aaagtgaacacacatgctggggaagaggcctgcaggcacccctgccagttctgcaccagagcacactgtagcagccctgc tgtgatgcaggaagcagctccaggtcctgcagtctgaagcatggagcctgaagcctggagccccccatccaatgctgcgc catgctcaccagtatcccccagcatcagcaccgaggcaccagctgcagataaatttctcacctaaaatgttgagagatgt tgctaaactgtccttctaagggtatgtataataatacggtcctgccgatactgaataagactatctgtttcattacatcc tcacaatactgaatatcattagcaacttgaattttaaattgtgctaatcaatgaaaatgattgcctaattactagtgagt tgaggttatttaacattaatactccttctgatgaaatattttgcatttatcacattttacataaattctctctatataat tagcactagaatgtccgacttggttttcattgttcctcacctgtttggaaacacattaagaatgagggagagaatggatg gggactcacctagggatgcatggagctggtcggcagccactctgaggccctcttaacacttccccaccacacacttaatt tcccctggtttgtccatagatacatccaacaatttttatgtaaataagaaagactcagctttcaatggaaaatggtaggt tggattttatgactgaagtggcaaaaagaaataagggattttattatgggggaggtccaaaccctggtgaaaaacgaaat tcattgaaattgtttgaaaattcaaggattaaatcagattattttggattcagtaggaattagattactttaaagcccca ggatactttattctgtagaatgcatggaaagtatagaaaagagaaacaaagagggaaagtcatggctaataacctggaag gggtaaatagggagccaaaggcctgtgggacgtaaccaactcagcattccactggaggctttatgatcaaatagcaagct atttatcatgaatgcaggatgtgggcaaactcacgactgctcccactgccagaaggtttgctgagggcaatcacttcctg gcaccgagctccttgaggttatctactgggacatctggagaatgcagtcttgcaagcctactctggacccagcagctgac ccct cttccatgcccctcttcctgctatctcttttgcctaataaatatggagggctgtgtaaagctcagggcccttgtc cactagaggcaaactgcccgctgaccccttcttccaaatatgctcttttgtctcatgtcttttattcccgctttcacccc actttgttcagtccccctagggccgtgtgggttacatagtggcgccctgaacagcgacagaatcaggtgctctacaagtg gcgtccgaacacagggactatgaggatgtgaatgaagaagatctgctggagcagaggaattgaaattgacaaggtgaatg gggatcccgggacaagtctgccggcagcagatataaggtcagtgccctaaagaggtactgggagcagtgccttaaagtag tactgggaatgggaagttttctgaatcagggtaacatggggcagaattggtctgttgaagaaaaacattatgtgcagttg cttaaagttttgttgaaacaaactggtgctcaggttagttctcacattaactacgatgctacaggaagtcattatgcata acccatggtttccacaggcagggactcttgatgtagaaaattgggatagagcagaaggattaaaacaggctcatcaaaaa ggttttcaagttgattcttcagttttctccacttggagtttagttcgtactgtacttctgccattatctccttgttattc tgcgggacagcaggctgaatgtaaaaatctgaaagaatctgttgtcccacccacagctccagttgaaaataagtaatagg agagggaggataaaaattggcctataccgccccctccagttgcagaaacatctgtaccgcctccttcggtggcagaaaca gagaccccaatacaaagaattttacgctctgccgccacggctggagagcccttaggaccttgcacttttcctatttccgt aagtcctgatccaaataatccacagcagcttaatcatgaacacattccactagagtttaagttgttaaaggaattaaaag tgagtgtggtaaataatggcatacagagcccattcactttaggattgctagaatctatgtttggtgctatgtgtctttta ccctttgatgtgaaacacttggcatgaacttgcttgtctgctagcgcatatctgacatggaatttaaactggcaagaaca gggtgcagaccaggctagacagaaccatgctgctggaaatggagacattacagaggataggctattgggtaatggccctt attctgacctggtacatcaactagcactcacaaatgctgcttatcagcagtgcacacaggctgctaaatgtgcctgggcc ataattcctgaagagggagtcccagtactatcatttttacatatcatgcaagggtcacaggaaccctacgcacaatttct tgcaagattacaagaggcagtgaggcatcagattcctcataccttggctgcagaaatgctaacctttactctagcttttg agaatgcaaatgcagattgtaaatgtgcactggcaccggttaggtgtacaaaaacttgggaaattttctcagagcttgtt aagatgtagcaactgagctttatcgatctgcaatgttagctgaagcaatggctaatttagctgttgacaaatctaaaaag agccaagggtcaaaccctaaaatgggaaaatgttataattgtggaaaaactggacattttaaaaaggaacgccaccagat ctcaggacagaaaggatcttacaatgcttttccccccggcccccagcggaaagaacacctggactttgtcctcgctatga caaaggaaataactcggctaatcagtgctgctcaaaatttcatcagaatggcacccccctgttgggaaatgagatggggg cctgtacccgggcctcacaaacaatgagggcattcccaattcagacctcaaccctgtttcaggcatgggttcccagaggc atattgagtccctcacccgaggaactccaggaagtgcaggattagatctcccagccagagaaagggttacataaggtggg gaagacaaacccaccaagattctcactggcatttggggacctttaccagcaggatatatgggactaattttaggcaaaag ccaccttaacttgcaaaggcattactgtagtcccagaagttgttgactctgattatgaaggagaaattcaagtagtttta ttgtcacgagatcttcgggtttttgaaccgagagaatacataatgcaattattacttattccctgcaaattacacccttc tccatgaaaggagaaacaaggaaataaagggtttgggagcacagctacacgggaaatctatctatcccgacccatagcct ctaatagacccacctgtgtagtacaaattaaaggaaagaaattttatgggtttatggataccggagctgatgtgtcagtg ttaccagcaggtctttgttcttagagctcccaagatggcggcaagccttttgttctctgacctggagttcttggcctcac agattccaaggaatggatccttgggccatgcagtgagtgtcatagctctattagaagctcttccaaaagtcgtgctgcta tctatggactaaaacatactcaaacaataatgacctctggcgtttaggctcaatgctcagagctaattgcagtcattcag gttttacagctcacagcttcagatcctgtcaacattgtctgtgttcagtttatgtcgtaaatgtagccggtcacatagaa actgctacaattaaaagtacgctaaacccagaactgctaatttatttttaagacttcaacaagttatttgttctagtgca gctccttttcatatttctcatattccttctcacacacaacttcctgggccgctatctctaagtaatgagaaaacagacaa actgattgcctctgtgtttcagcaagctcaaccatctcatgtgcttctgcaccaaaatacttccgcccttactcacatgt tcctacaggtttgtattatattatgcagtatatccctcgagccacacctatagaaggatgtaatccacgaggtttggctc caaatgaaatctggcaaatggatgttacacacacagcaacctttgataagctgagctatgttcatgtgactatagacact tattctcatatgctgcctgctacatgccaaacaggtgagacagctggtcatgtacagcgacactgtctgtcatcatttgc catatggggatatctaaacaattaaaaactgacaatggacccgcttatactagtcatgcttttaaaaatttcttgcagc tttgggctataacccataaaacaggaattccttataatcctagaggacaaggcattatagagcaggcacatcaaacatta caatgcatgttgaaaagacaaaaagcgggtataggaggccaactaccacctcaataaaaactacatttagccttatttac tttaaattttttgactcctggtatggatggtaagactccagcagaaagacattggcaagtgttagaagaaaagaggaaaa tttatccaaaagtgttatggaaatccctggaagaaggaaaatggaaaggtctggtggatttactgacgtggggaagagag tatgcttgtgtttttacaggagatggacaagccgtgtgggtgccctcaaggtgtgtgcaaccatggaacgggagactaga ggaacccagggtggccaaccatggacagggtccccccggtacgagccatgagccagctgagcctgagtgcaaagacggag agaaggccaactggagtcacaacacagttctaatgttatatttgtaaagaatatcactactcaacttacagtttgtgttt atagatatagatatagatatagatatagatatggatatagatatagatatagttatagatatagatagatatacacttta agttctagggtacatgtgcacaacttgcaggtttgttacataggtatacatgtgccatgttggtttgctgcacccatcaa ctcatcatttacattaggtatttctcctaatgctctccctcccccagcaccgcctcccaacaggccctggtatgtgatgt tccctgccctgtgtccaagtgttctcattgttcaatttccacctatgaatgagaacatgcagtgttttattttctgttcc tgtattagtttgctgagaatgatggtttccagcttcatccatgtccctgcaaaggacatgaactcatccttttttatggc tgcatagtattccatggtgtatccttatgtctttttgacagctaagaaggaccagctccaggtaaacaatacccaattga cctgtaaatcttaccaattatatcactgcattaatcatagcacattgcaaacacataatatctctactttgatgatttta ggccacatccctgggctatgtattcctgttaatctgtccgaggcttgggctgccacacctgctttgcattttgtgaaact tcttctaactgagcttactcatcatgtctgtagagccttagacataataattttagctattgtttccttggtcgcactaa taacttctgttgtgatgtcctctgtagctttgcataattctattcaaacagctcagtacatggagaactggacacacaca gccgaccaagcatggctacttcagaataaaattaacactgagttacaaactgaagtggtgttatgggaagtcagggaccc caaagagagggaccagctggagccacagcagaggaacgtaaattgtgaagatttcatcttaatacggatatttatcagtt ctcaaataatacttttacaatttcttatgcctgtctttaatctcttaatcctgttaccttcgtaagctgaggatgtgcat cacctcaggaccactgttataattgtgttaactgtacaaattgattgtaaaacgtgtgtttgaacaatatgaaatcagtg caccttgaaaaagaacagaataacggtgatttttatggaacaagggaagacaaccataaggtctgactgcctgcagggtc gggcaaaaagagccatatttttctttttgcagagagcctataaatgaatgtgcaagtaggaaacatatcgctaaattctt ttcctagcaaggaatattaatattaataccctcggaaaagaatgcattcctgaggggaggtctataaatggccgctctgg gaatgtctgtcttgtgcagttgagataaggactgagatacgccctggtctcctgcagaaccctcaggcttactagagtgg ggaaaaactctgctgtagtaaatttttggtcagaccagttttctgctctcaaaccctgttttctgttaagatgtttatca agacaatacgtgcaccactgaacatagacccttatcaggagtttatgatttttctcctgtcctgtttcctcaggagcatg tgatctttgttctcctttttgccctttgaagcatgtgatctttgtgacctactccctgttcttacaccccctcccctttt gaaatccttaataaaaacctgctggttttgcggctcaggtgggcatcacggtcctaccaatatgtgatgtcacccctgga ggcccagctgtaaaattcttctctttgtactctttctctttatttctcagccagccgacacttatggaaaatagaacgaa cctacgtgaaatattgggggtgggttcccccgatatgtgatgtcacccctggtggcccagctgtaaaattcctctctttg tactgtctctctttatttctcagctggccaacacttatggaaaatagaaggaacctatgttgaaatactgagggtgggtt ctcccaataaagtggtaatgttgaaatccacagttctatggttaggggaaaagcacaaagcttgcaattgcagcagcaat tgcattgtcattttaatcacactcatatttgtgtaaccaacttagaatataaccaaagtgagtatctgtgggacgttgtg aaagcccatttgcagggagctttcacatctaacatcacctttgatattggtgaattacaaaacaaaattcttgatttaca taggcaaattcaagagtttctgccttctttagaagactggaccaaattccagcaaggcctggagagcctcaatccttgga cttatctaaggcactacattaacatcttacatgtagttcttggaataatattgttttgtctctgtcttctgttcatagcc tgtaaaattggatggaccaccaatcggaaaatgagagctgcccaccctggccttacattctttcaattaattcataaaca gaaagggggatatttagggagcctaaggctcgtgggactgaccaactcatcattccactggaggctatatgataaaacag caaactgtttatcatgaatgcaggatgtgggcaaactcacgactgctcccactgccagaaggtttgctgagggcaatcac ttcctggcaccaggctccttgaggttatctactgggacatctggagaatgcagtcttgcaagcctactgtggactgagca gctgatcccttcttccacgccccccttctcactatctcttttgtctaatcactacggagggttgtgtaaagctcagggcc cttgtccactagaggcaaagtgccccctgaccgcttcttccaaatatactcttttgtctcttgtcttttattcccacgtt tgccccctttgttcagtttccctaggtccatgtgggttacatagtggcaacctgaacaatgacagaatcaggtgctctac agaaataactttttaaggaaagatttgggacttagagaccccaggagacatacacaaaaatgataagaggatgtgcccaa accagtcttaaagttgtggcacagggtgaggaagatgaagctgttactgaacctcagagagtgactggtgttacagcaaa agttagcaatggcctgaagggagggtttctgaaatcaaatatgaatgattccccctcagggaacccaaccttgggaacta ctgcatggttctctgtatgggaaaatatcattaatgcaggataaattgtgaaatatcacaggaagcatcctgcatctagt caatcttctgtttctggggtggcctgtgcagctgtgcaggcagaggcccaaccatcctggtgagtggcacacagggactg agatccagccacacctaccaggccatgctctgggaagggggtgggacctgggcaaaggacacctctctaggactgcacag aagcctttgtgggtgggtgggacattcctgtgatggccttctggctgggcactatgaaatgctctgaagatttttccttg cactgttgcactaaccccagtcctctatcactgccccttcctcctgggcgacttcactgatgttgtggccatgtgaattc tctggccaatgaaatgataaagatgatatggcctctgccaagcagacactgtaagtattattgtatgatgcttttgtctc tttttttaaagttaaagcagtttattaagaaaataaaggaataaaagaatagcactccataggcagagcagctgcctctg tctcttatattttcccctctgcctcaagcccaacatgcccaaaattggggctgctggttcagcctgggtctcagaataaa gacatgagccacagatccattgctgacccatgatggagatggacacaagagagaaacacatttttgtcatgttagccact aagattttgatttggaggccatttgctacagcaatataacctagcgtgaacagagagacacagcgatgttccatttcttt tcaacctggaacaggagaatttcataggtgggcctcaatttcactttagtatcttatttagacaagaaagttcatactgt tcaaatgtcatgtttaagagtgctggcattatcactgctgtggctaccccatcagatgttgctcactgactaatcttctc atgttagtgaggatggacaacatatcaggccataattcaaagtagcaaataggaaaagagcttcatcctagcattatggg accttaattaatgtcctttcctgacaggtttcagaggcttttgcaggcagcagcagagctattcatctcactgacagtgg ggaacatggccaaatggttgcccccacaatggaggcagagtttcaggacacttgtctgatctctgcccttgaaggaacag tctcaccctgattgacacttttgcctgttatgtccaaagaaccaatggaaaagcaggaaaattattccttcttcatttct ctcttcattatttaaaattattctgtcttcacttctctctccttttctctgcttcctacttagctctttagaaatgcaat tataatcttttatctccccttcaccagacactcccaacagggcaagttcatctaactatgtgctcttagttagacgctac agagcagaactctctcccaccaagagactaccttgagacataacagtcaattcacaagccaaaatatgcccgctatgaaa ctctcccatctggaaattttttggctgcttttacaacctagttttgcccacaaaggcaccagcagtaaccaactcaactg cctggtagacaaggcaccaaagccagtacccagaccctctacctgctcacttcctgccttgcatgccacgccccccattt aaaagcctctgctttctgctccaaaggtgaagcagttacccttaaggaaagaagcctgtacttcttcccctaaggtagct ttggaataaaagtcactttataccaaacctagctcttgttaattagactctgcaagtgatgagcaactgaacctacattt cagttataattcctatgcttgttcttcctgccctgccttggggacacgcacacactcccaggcacatacatgcacgtgca ctgagacagctatgtgaataaccaacaagatccccttaggaaaaccggtgcttggcctggccttaaattccagacccttg ggcatcatacccaagactgcaagaaagaggaggggctggacctgaaaaacttggaagggaaggtccaactgtacaggtat tttgtcaggcatgtgatttcagtataaaattctagaaaagatgagtgacactttataaggagagaatatcaacaaaattt ctcattttacttcttgctaagacgacagcagggaattgtaagcagatggatgggcaatccccaccttcagcaggggaggc caaggccccaacacacctggggagaagagctgggggcagtgaatggctgaggctttcttggggagctgggccatcttctt cggttttacttcctgaggaattcacaggcttccaggagggctgtgggacacaacagagcaagagattcagaaactgattt cttccattaaaccagttatttaatccaataaatcaaagagaatactaagagttttctctgcccttctcccatcactgagt cagtgcttgccacactcatattcccactcccctactcctagcgactacggtgttcaagggagccagagtctagccctcac cagccagggtgtttccctgctctggcctgagagacacaaccaccctgcacttgtctctgattgaatcgactgtcacattc tcaagttcacaagacattggtggtcctctagcttctcccggaatgtgaacctgtttgcaatcatgttcacctgcagattc actcattcattcacagatccttactgagcacctgctttgtgtgagttgctgtgctaagtgctggggacacagcatggata gactggcctgccctcaagaagcatgtggtctatgcagtcctgagctggctgctcacaagaagagccctgtagccatattt ctcagagggtggtcctgacctgcatcacagtgacctgagttgtttgtcaatacagaaaagggtttctcaaccttggcact attgacatttggggcctgataataaccctttattgcagggggctggctgtgctttgtttagtagcatccctggcctctac ctatttgttaccagcagcaccctctatgttgtaagaatcaaaaaaatgcttctcacattgtcaaatatcccctcagggga aaaattgtctctcattgaaaactaccgataaagacatttctggccctgcccccatccttggaccaacagcatccctaatg cccccaactctgggtgagggaccaggaataggaatctgaatgattgcagtgcacagggagctgtgcacactgaaatccca cagttatcaccgggagccttacaatactctgtgatgtcttctaaatatttttaagggattaaattaatatcaacatattt ccctggttaagatgtgttttcctacacttgaatttttttgagattttgttttctctatagttggcatctatggtaactgt ctagaatcagatttttttttttttttttttgaggaagggtctttcggtgtcacctaggctgtagtgcagtggtacaatca tagctcactgcagcttcaaccttctgggatcaagcaatcctcctatttcagcctctcaagtagctgggactagaggtgct tgacaccacaccaggctaatttttaaaattatttttgtagaacaaggtctctctgtgttggccacattggtctcaaactc ccgggctcaagccatcctcccacctctgcttcccaaggtggtgggatgacaggtgtgagccatcacacctggctggtttt gtcatttctcaatgcatatgtatatatgcacctttcattttactgaataaaatggattatcagtttccaaagatttcatg acagtgccgtcactatccgtactataaaatttataaaaatttattacatactgctctattttattctctaattattttat caatgagattataatttcctgaactgtaaagagatattatctttccttaacatttttacacctgtgttcgttcctagaat gctgtttggccctcaaaccttgaccttcacccatggtggtttctcggggatgctagctagggtctacttacgggaggttg agcactttttcagattagtaatgcctgcgacatactgtggtcccaaatatttttcatatgttgttttgccatggagtctg gccagacactcagtgttgtcattgaacagaaggtttttggtttcagactggaataagcaaaacttgtccgggcagtcaga tccatttctcccaaatttagcctgcgacaaaagggcagacagtgagtagctaaggaaaagaggaatttgtgggttaaagg aggcaaaggggtatttcttccacccaagaacagccctgagaaaaccatggggcagaaggagctgagttctggagtcattc cacctccttagtggagtcccccaccccacactcctggtggcaggcccgccttgggcagcatccaggcctcacaccacttc tggtcctacctcctaccatctgccatctttccttccttcttaacctgtgaccttttcccatacaacttcttatgggtgac aaggcaacaatggaggggttttgagatctgccctcacaagtcaattgctcaggacattctaatatgcagctcttctagag aggcaggctgctaggaaaacccaggctcagccactaaccagctcagtgtgcaggtcggtcaccctgcctccctcacacag ttcctgctctgtcccaggctcccatgtggggagactgagacccaaacccctcagtcacggcagctctctcaccagcacca ctgtgtgtgcacattaagagctccataaaggccagttatggtggccagtcttgttattcctgagttgttttcttcaaaag cacacagagacatgatgttatatgataaaaatagaagttctaataaaatcccagattttaagaaaattttgggatttcgt tcaaatcacatttagagagccctaaatctatagggcaccttctgagtttgctgttttagaggcctggtctagagcactgt tcactcggcccaggttcaggaaatgtcacctgagtaaaaagcactatactaatgcatgtgggaggaaggctcagtggctt cctcatttgccagaagaacagcaggagggaaaaagacagcctctgagccaggcagtgatggcaacaaggccagggcacag agtctcagcagaaatggagtgagtcccagaaagcccagagtcaaaagcctctgttgttcttgttgacactctgggcaacg ccacagcatgaagccaatactctcaccatgagcttcaagtagaggactagagaggatcgagtgggctggtgcacctagct ctgtgatctcctcacctaacatgagcccacacagctaagaaagcactagaagccctgtggtccatacctgttggtggagc aacacctgtttcaggcgttccaccttatccatccgagacaccacggcatgattcggggccatggcaagatggcagcttct agcctcagtcacaggcttccgtttgccatcgaggcacagcagcgcaaagtctgccagcttcaaatccttagcccatgcgt cattgttatttcctggggagaaaaagaaggtggcatcatccacgcctcccctgcttagccaagaagtctcttctgggtgg gtgtggccattccactgacctcccaaatgcacacactggggttgtggtgatgtgaggaacagagaaggagcttcatccta cacaagctgtacaaacttcaaatataccaaatattagtgctgtgtccatgcaatggaatgttattcagcaataaaaggga gtgaagttctggtacatcctgcaatatgcatgaacctcgaaaacgatgctaagtgaaagaagccagtcacaaaagaccac acaataggctgggcacggtggctcatgcctgtaatcccagccctttggaggccaaggtgggagaatcacttgaagctagg agttcatgaccagcttgggcaacatagcaagacctcatctcaaaaaaaaaaacccaccacatattatatgactccattta tatgaaatgtccagaataggccagcctatggagacagaaagtggattgatggttgccaatgctgaagaaggatagggcaa tgactgataataggtgcaagggtttctttatgggaggatacaagcgttctagagttggattgtgttgatggctgcacaac tctgtgaatgtgctggagatcactgaattgtacactttgcatgggtggattttttagtatatgaattctacctcaataaa gctgtttagagttcttatttttttaaagaagaaaaccctccacctatgccatatttttcagtgagttccagaaaaagaat agatggtttacattcaaggagaaattggtttctcctccctttcatattcaaatgctattagtgtaaccagagaaaggaaa ggaacttttataggtttatcaaatatatacagccaattctaacaaaatacagttgtaaagtaccggagaaagttaaaatt aaatttgacatcaatctgatccctggagattacttcagttaatggcttgtaaattctaaatgtaattgtatgcatgtcta tgtttgtgcagatgccggctcattgttccggctcccgtttgtctctctgctctctccctttaagaaagcactttattcat tc cttggattcctctatttgatattgaaataatttcaaatttacatgtcttgttttaatctctgtcccaagagacacta gaaggagcagaagcagaagggagaagtggctgagactgcagtgattactgaaggagggaggccgaaagtggagacagttc tttctcaggaaacagaatagcaagtcacctgctgagacttgggggttggaatgctgaagtggggctaaggagacagatgc agattggaaggtagcaaatggctgaggaccaggagagagagtgattgttcaaacattggctggaagattatcttccatca tctgcaaccacctgtaattttgttcccactaactcccaaggagtctccagaccaaggctcacatggggatgaatgaaggc ctctacttcctttttcataaagggaggcttcatttgcatatgttcacccagtttgtagcatcatccacagtttccaatag gcatgcatgatctcatgtgggcagacagtgtgtttctgtggttgactagaggaagccagggagacatttgctactgagca tggctagtatctgtgtgtgtgagagtgagtgtgtgtgtgtgtgtgtgagagaaagagagagagtgtgtgtgtatgaattt cgtttcaaaatccatatgacacctacagatgttatcatgttgtctattgagataaagaattttggagttcttttaatcac aaatatggaaaatgttataaaaccttcccaaaggcaaatctgaacactaagatgtgttgtgatgccaaagactctgcttt gaaggagaaaaggaaacaccttcacctaccatcagtgttctgcaagacagtgacatctttcacaaatgcaacgtctccag cattctcagccaggcacctaaaatgttccagaaaatatacacataattacagaagagaaactagtggggctttcataaat atttgtaatatgcattccaaaaactgaaatatggaagtaaacatctaaaagacaactatttctaggaatttactgtttac agcggcagattgaacacaggtgtacctgccctccttttaaaaccctatataaaagacattacaaaaccaagaaatctaaa gatatgcgacccaggaaacaggcaatctaacatgaagtaagacaaaggaaagcaccaaaataatggtcaacaggaccccc aggaccacagatgtgcaggcggcctacacagcaaccagtccaaactgcagcaggaagatggatgccttctggagcagcac ttccaagtaaatgatgaaactgtgatagcacccagagagagagagagagagagagagagagagagtgtgtgtgtgtgtgt gtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtatgcatgttgttaggagatttacattactggcagacagtttgggga tgagatagtgatgtgtttttttaagtgcagaaaattaagcaaataagaaaagacatttatgaactccagagtaaacaaaa agtttgtacaataagggaaatataatatgagaataacgcttacacagtcataagtactgaatatgacattagcgtgttgg gtgctgaagagagttgaagtctgtggttgtgtggtggaaaaggtgctgggggcagtgtgagaggctagatcttcttctat actacagagtcagcagaaagttaaaaattaagaaccagcattataaggatgatagaaataaaggggtatgacactggttt cagcttttaatgattttgctataaatttccccaatctagattctagatataatttaaacaaaagacaagggattttcttc cagtataattaggaatattaaaatgtgggtgtttccagtgaactaataccttgctgcaggtctgaaaaaaaaaaaaagag gagcacatgcttctttcgggctcttatgagacatgtgttcagcatttctgagtagaatcacatttccatttgcaaatcct tagtcccttaaagatatttttatacattcacaaaacatttttttttgttttgggtctttttttatgagccacttatatag caaaagctacttttctgtcattccattactggaacaaggctgttgaatttatattaaaaagttcagacaccctcagacac atgacgccatctggtcgtgaaatgtactcttggcaaatggaggaaaaggaacaggggaagatcctctctgcacccttcac actggtaaatagtgcccctgagaagcaacacccggatgaatggtgctgtaaaacgtggggtgtggttacaagtcactaag tggttataacttatgaattctgaaaacttgttttttggcttatttttcacttcgttactggagaataacactgcaattct gccatctctttgccatttctaaggccaaagtcagagaaaaagggaaacctaagccatagtcatgacctaggtgagaagaa aaggggcggcgatgggaaagagaattcttccccataaatggaattgtaggaagcacttaggataccacactctacccatt tgattttcaggacgaggctattgaggcctactgctgttgatcttggctcaaagccacagggagaagcactgcggagctga ggtcagacagccctggtgccagcctccactctctggggcggtgggtgtggtggggacagccctcactggggccacccatg agctgacccacaggatgacccccactctgctgtgacaggtcacatctggctccttagaactgcaatgctgacatgctgag ggatgaggtaagtccccatcctgatggagctcagtcacagactcaccggaaagccccagtgtagccgtagtatctctcgt tgctgttgggcacgcacttattctcaccctgctcgtcgccaatacacagagcacagagattagatctcgggtcagaccca ggggcacagctttgactgaaatattcatctggagagaaggaacacggggagtcagctcttcaaacctgagtccacacaag caacctttacctaacagccgatgcagggtggtttcagttcattagacttcccaggacagcaatctagatagaacacactc accatcacaaagcaacatgttgtcaccaacataggacccaccagaaaagcttcattcagactgtaggcacagatggacac ccaactaaggctggggatgagagctgtggctgcctggagggtcccgtcatcacagccttgagctggggactcagctcatg ^• accgtgatggctgtgtgcagcagagcctgtgagttgcctagtccaggatctgattttgtttttatcagtaatggaaaccc tgctttgtatctgggtgcttggccctttggtataaagactagacttatcagactccctggggctcatatggccatatggg tagctataggccagtgaaatatcagcaggagtgttgggcgccagcttctcagaaacatccttgaaagacaattggtacat gccttttgccctttcttctccttctctttcttcatcctgcacatagaatgcagaagcagggactggacttagagatgcaa tgtgggccatgaggtgaccttgagcatgaaagccacacaaatggcagagtagccaaatgattaaagcccaggttccagac cccatattgtcttcataccagccctaggcaaaccacctctggactacatgacacagaaattaacttctgtcttgtttaag cctctactatttcaggagttttctgttccttgcagctgaacctgatctgaattcgttcattgtgtgatttaacccaagaa agaataaacaaaggtgacaagaaagctctgccccactgagcaaacgtcacccattatcagactcccactgctgctggaag agccacactatgtgtcaacctcaggaaaagctgggagttcccattccatcctggcagtttccctacagctcagaggctgc catggagctggtgaggagcagagccacgtgaaagctgcctgccccggccaggatcaaaaacccatgcagtggagcccctg ccctaggagacgcccatacaagaagggagtcacattgaggatgtgctacacaccatgccacggggcccacagcaggcagg gtgtggctgatgctgactaggatgagtgtggggtgtggtggggagagaaaactgcagaagcaggtggagccaggctcttg aggtcttattcaggctccgttgcagtgtagagtaagcgtcagttttgcttagtaacaggagtcacctttcatgaggcagg cagacatctttccccaagctgggaagccagagtttaagaggaatttaggtctggagctccaagaggtaaaaagcatttgc acatcttggaacttgcatttattcttagggtgcagcgaaataggcagatattccaatctttaatcttggggtggggtgaa tggggcatgggaagtgctgtgcagggaaacccccagtgcacccacgcctccagggggcagccacagggagaatttcctta tgctggaagaggcctgcaggccactatcagcctgcaaatcccctcccctcccttccctaaggttccacagcacaatatgc ctaccctccagggtggcccacccaccgcacctttggaactccttaccaaatttgcaggagcccgtctggttgaagagcag gcccatggggatattccagcctgcagtcctgtccacggcggtgtggcaggacttcttgcctttcacagagttccaggtaa ggctagtgtctgatctcctaaccaccgccacagcaagatatcctggcataacagatgacagaaaaacaagtcttaacctc caggaggcctggcacatggattccagtggagctgtctacagcccaggccaaaacaggccaagaagcaacaccaggcaatg attccctcaaagaactggcctttttaggtagaccgagaaagcataagctgctgccttatgttaaggtgagattgatgaaa taaaacagtaagaaaagctgattattttagtgattacaggggactgtcttcaaccagccacacaatgtccctgagttaca aaccagcaatgcatctctcagtgtaagcttctacagcaacaaacactataaacaacaagagagaccccaacagtgcataa atcaccaaccacagtgtgcatcaggcaagagcaccaacatccagccagctaacggctgtgtgggtacaggggcacatgtc cccagggactgccctgagctgagtctgaacccaccctgcactggttgaactcaacatggttgccgttgtcctcctgagag aatgcatctgacagacacccaccaagggcaagtcttttctgaaactgagcaagcaccagctctggtgggcaggaggagtg gtgcacagagcactgggacacgagtcccaggtcacgaggacccggggtcaagaccaggatctaccacagtattacctatg gctgtgagtgagatcctgggcacttggggactctcggtgccactgtttcctcatccccatgaggtggggaagtagcaccc cccattccatgaccatgacaaaatgagggactatatggatgttctttgccaagtgtgaaggtcaatataaacattaatta gaactattcctctgtgaattatttgcacccttaaaattattgctcctagaagccctatagcttctagggctgcaattctt tctgttttttttacagttcctgccacttcctcttccagcaacaagaacttatccttgaccctgaaagtggctaatgccaa ctcaccttccacaggtctatccacacagttaggatcagggtcactgctttgttgggattctgaaagaataaagacaagcc agacatcattatccattcagatgtagtgagaagccacaaactcttaaatctcaatgatgcagaatcaaatccaaagagac cgtcccagcagttccatgcaggagaaatgcgtctatatgttcaacaaaagacatggcacagagattcacagctgcattat tcaccacagccaccaactggaaactactcaaatgcccatccacactcaaatgatgaataatcacagtagactcacacagc gacgagactgaacagtctacaactacacacttaggtggatgaaaagcataacgatgagcaagagaaaccagacataaaaa aacacatgctgtgtaattcctttaacatgaagtttaaaacataggcaaacttagatctgcgaccttagaagccaggagag aggcttcccttgcaggagtaagggggcgggggacaggaggacataaggggcttctgaaacttgcagtgtttgttctgggc ccgagagcatggactgtacagtgtgtgaagtgccatgagttgtacatttatgtgcacttttctgtttgtatgttataatt cactgagatcttctggaaaattaagaagataaaaccaacctgtcccttgttaattctcaacacaataggctttgtgggta acacggcccctttcatttcttctttccctgattctcccttttgaatgtatctgttcatcataatgtttcacctgcattca ccgaatgggattactcatagccccactcccatgacccagagggaatataccagaggatgctaactccacttactgtagtt ctctgccaggacaggcaccaaaccacatttgcctgcagtgtacacatatcctccatccaaactcatggcatcagcttctc ctttctgcaaagacagagcagatctccagcaccacagtgaggctgcatcccgtcctgcctgtctatatagctctctgaga gaatggttttctgtcaggtgaccagtgaaacagcagaaagagatggactattcaaactgagcagccagaggaaacaccgt gtgcaccactaattctctcccagccctgcctactttctgggctgtcaattcaactggaaagaccaggcacaggttgcact aatcctctgtcctctgagcaaaaccttttctgtgtccctggcactttggggacaccttcctggagcagtctcactgactg aggacacagatgggaacagctggcc catctaatctgaactcattagcactccactccaagcgctacacagaagttgtcc aacacataagctgaagtcgtcatattggcccaccaccagaatgaacaagtccaggctacaacacaggatcatggactcat cagtagtatgaaacttcctctttgacccagtaatatttttacaactatattaaaaatagagaagtggacaaagatttcta ctcaagaatgctcaccacagggttattgataatagcaaagtaagggacaaagaggaatgggggcatgactaaactgagcc atattcacataaaagatatcctggaagcatgtttaaaaaatgttttcgtccgagtgctgtggctcacacccgtaatccca gcactttgggaggccgaagcaggaagattgcttgagcccaggagttcgagacgagcctgggcaacaaagcgagaccctgt cgctacaataataataataataattatgcaggtgtggtggcgtatgcctgtagccccagctacttgggaagctgagatgg gaggatcacttgagcccaagagttccaggctgcagtgagatgtggtcgcaccactgcactccagcctgggtgacagatca agaatctgtctcttaaaaaaaaaaaaattaatgctttccaagagtaaatattcatgtggaagaatgcccattatacgctg tttagtgaaaagggcttaaaaacgacatactgcaacacttcattattgttgcatgcatatctgcagatgtgcagagaaat actggaatggagaattagccagactttaaccatgtctgtccctctgtgtgagatcacaggtggtttggggggtttgttgt tgttttgttttaacataatacctttccatattttccaaattccttataataatcctgagttgttcttataaccagaggag tgggaaacccacagtaaactgctttttgaaactaaaatgctttctggccctgagcacacctctccaggcatccctgcctc acccaggcccccgtggcctctttgactgttgacttcactttaagcagatgcccaggccctaggtcttccaccgggcccac cgcccgcccctgtgatggagctccctaccagcaccagggcgatgcagtcctctgtggtggaggccgaggagcaggtcacg ctgccttcgctcaagccactccactggttacacttgcgcagctcctgctcgcccaccgcacaccacacgacccgcgcacg ccgggcagccacttcctcctcacctgccagagggaagaccgcaggtggctgggcaacctgagctttgccaggttgtccaa cctccccagagccagggtcctgcccagactctccctggaacaggagctacagtacatgtgtggacatgtggacccatacc ctctcctcctccacttctcagctccaagccccttcttcaggtccacagagctccctgtgtttcccacttctgttcctttg gagaagttccctggcttctaatctatccattaatctttagagtcaggaggcgcctattgtctctgtctctgaggataaac gctccatgacccagagaccagtgacagtcccaagagatggcctaggggaccttgagcccaaccctgacttcccctaacgc ctgcaatcaccaccaataactacggtgcagcctctgggttcccccagactcccacccccagccccccagtagagaaggag ccatagctgagttcccccaccatggtgtccccaactaagttcaaggtctgggcctgggaagtgtgggtaaatccaggccc ccggattcatccaggaggggtcctggctatctttgttcatgttcatgtttctcacttaataggaggcaaactgatttttc tgccaggcctggggagcctgacgtgcactgatcaggtggccagactattcttttagagacacctgacctaatccacagaa gacactcacacctgcatcaaacctccacgatgaccccacagtgtctgggaaaaggagtgaccgccacaaagtagggccac ctgctgggaagtagaagaccacaccaggcggacctcaggaccctcctgggctcactcacttttcctcaagttctggatgg cagtgaagtagccggagccaaggtacagcccagaatctatcctcgggggcaccctcgaaaacccaatggcagagtccttg aacagcagatctttctgcccactaggggagccaaagagctggaatttcggtgacttgtcctttccaaacttttcctaatt aagaaaaaatagaattatggtgtcaatggtaaatagggaggaaacaaaaaaatgatgttaaaaaagagtatctggagctt tgggatcattctaactgagagcaggagcctcggttgagaccctcctgcagagggacttgtgccatctcggagacccaagc tcagctatggctcattctttgaagagttgctgaggtccaagcaccttagggccctgagaagattgcatcgaccaccccct gcttctgctcccatcataagacgctgtcagcccgtgtgacagaagagtttcattgcttctgctgtccacagtacagcctg ggcaagcagcccaatgcattagtgtgctatcctgcagcaaagctacaggacttctggagtggcagaagtcagggaagtaa gaaaccttgctccctgccccccatatccaagcaagtggggaggaccgtgggtgaagatacctgtgcctggcggagaagat tccagatggcatcctccttgccattcacacttcgtgccacaacggcatgagaagggacccgggccagatggcagtctttg aacttgtccactggcttccgagtgttgtctgggcagagtaactcatactcgtccctttcagcctcgtctgacaggtcctc tgcagggaaggtgaggtgggagggagtctagataagccgactccagcagtaacctcgagctatagttccccttctcccta tagaattttgagcttggggagatagctgacaaaactgagggtcagaaaggcaggggtttgctccagaacactcagaaagg taaaggtagtgccccaaaagcctcagggggcagccgaggtgtgatcctcatcctaaatcacttaggccaccctggggttc ccgtgcagctgctgcctggcaggccagagaggccaaaccagacccgtctgtttctgcggcatctctgcctggaaaagtca ctttgcagagacaagctcagggggccaccaagggttgctcccttactcacatctctgggaagaataaaaatgacaaaaat gttaacaaggcagggaataaggcaggaaggtgagacactttccaacactgagtatatcaaaagaaggggaagaatggttt tatgaatgagttcaggcaaatgtggaatatcatatataagttgcttcagaatgtgtaaagtgaaaaaaatcttgcccgag tcattttatgagattagtacaaccttgatgtcaaaatcagaaaaagtataggagggaagaattaaaagtttattttactt acgaacataaatgcaaaatttgtaaataacgtactaactaactcaatctcacagagtatttaaaaagctaatagattgga atgaaggtttaccagtgtattccattaacaaaagaatggctgaacatcaaaaaaactaaagtaatctgcatttaatggca gaaaaccatgagatcgtcttcatcttaatagatgcagaacgattgtttatgtgttcaacatctatttgtgtgtggttttt ttttcagcctcagaaaaatagtaatagatagaatcggtaaagtttttttgtttgttttgagacggagtctcactctgttg cccagcctggaatgcagtggtgcgatctcagctcactgcatcctccatctcctggagtcaagagattctcttgcctcagc ctcccaagtagctgggaccacaagcgcacgccaccaggcccagctaatttttgtatttttaatagagatggggtttcacc atgttggccaggctggtctcgaactcctgacctcatgtgatccacccgcctcagtctcccaaagtgctgggattacaggg gtgagacaccacgcctggccataagttattggcttgataaatgccattaatctacagcaaaaaccttactaaaagaagaa aatgtagacattcaccgcaaaatcaggaacaaggcaaggatgcccactgttacaatgccagcacaattctagatatccag atcacacaatttacaaaagaaatgtgagatataaacactggaaggaaaaagacacactcttatttaaaaagatgatatcg tcatctacaaaaaaccaatgaaaccaacagaaactaataaaactactcagaggagtaacaagttataagagcaacctaca aaaatcagatgttatcctcattaacaataaccaaatagaaaccaatatggactataagatgttacaatagcaactaaaac cattaagtagctaataattagcctcccacaaagacacatcagacccacaaaggaaaaattttagttct tcaaagaaact aaaaagaggtgtgatcaaatgggggagatttagcatcaccatggactggacaacttaatgttataaatatgctgattttt catggaacaatttaaattcagtacaattcgaatcaaaattaaagtatgattttttccagaaattcaacaaaataattctg aagttttagctgagtatatttgaaaaggaataataaagtgagaggggagagggagctctctctcattctctctctcttcc tctcactggctctctctctttctctccaccagatagtaagacccattggtaagccacagtaacaaaagcagaaaaaatgc aaatacaccaatgaaataaaatagctcagaaactggtccacttggatatatacaaacttggtgtagaattggcttcacat atggcagaaaaaatatactttttttattgtaaggtaaattgcctcactgtaaaggggataaaatgctaaagccaaatcta tatctgactttctaggtagagcacatataaatagatgaggaaggggatcttcaaatcttattttaggaaataattatgat ttgggtgtgaagaagggcatctttgaaatatctcaaaactacaaaccaacaaggtgaggcttgtggatttgaccttatca atatcaaggatttttgatcaacagagactaccgttgtcagatttttgactgagaagaggttttactaaagtttaaaatca gcaatagtttgatacctagatagaaggaacttctgtccttgaatcaaaatcatgcagaaacaaggtgtgaaactcaattt aaaaagtagtcaaatgtcacaaaataagaaagggaagcccaaacggctagcaaatatgttgaaatgatcaaactcaccag ctgtcagagaaatgaaaattaaaaataaaacgaactatctattgcattacaaccatcattcggacaaaaagtatgaaagt caaaaatacttctaactgaagttgtggggaaattagaacacttgcagagtgtcattccagacagcagcttggtgatcctg ggtgcatgtggggtctgtctctggtggccctgggtgcatgtggaggtctgtttctggtggcctctgatgaatgcggggtc tgtctctgatggtcctaggtgaatgtgggtgttgtctctttctctggtggtcctgggtggatgtggggtgtgtctctgat ggtcctgagtgaatgtgggtgtctgtcactttctctagtggccctgggtggaatatagtagccctgtctctattggtctt gcatgaaatgtagtgagcttatgtccactagtcctgggtgcagtgtgtttagcctctacatactcatcaactgctttatt ataagtccaggagggacgctgtccagcaggtaagtaaggaacacaggtgaaggtatcagtcgtgtggctgcatgtggtag aggaaaagagagcacaacctctgtccatcactatggtgacagagaagtaaaaggtggatgtattccacggaacactcctc aactgttaggacccctgagctagacatgtatacaacaataccgataaacctctaaaacaaaatgctgagcagaaaaccca agtagcaggatttctaatgctcactaaaacctctatgaacccagaaaccggaaacacaaaccagcacaatctgttctgca tgagcacatgtgtcttggaggactggaggacgcattgccaagcacctaggcatgggtgtctatgaggggaagagaaaggc agtaggcacaggaggtttgaagaaaactgatcatttaaaatatgaaagatcataaaatcagagctgtgccctgtaggaat cttgaaaatggtctgccatgaacttaggaatctaattagctcaaaggtcagagtcatgatcaagtaagataaaaggggtc agtacccacggctcattaccctgctcttaccaaacactgtgctctctctgataaaagccacgtctccagccccgtctctc agacacctgtgaaaagagaaaccatcaggggtaagcacaggcagccctccccagcccctccctgtggaacagtagccctg gcactcagcatctatgggtttctactccctgcagggcagggctctgaagcttaatgagttcaggcaaatgtggaatatca tatataagttgcttcagaatgtgtaaagtgaaaaaaatcttgcccgagtcattttatgagattagtacaaccttgatgtc aaaatcagaaaaagtataggagggaagaattaaaagtttattttacttacgaacataaatgcaaaatttgtaaataacgt actaactaactcaatctcacagagtatttaaaaagctaatagattggaatgaaggtttaccagtgtattccattaacaaa agaatggctgaacatcaaaaaaactaaagtaatctgcatttaatggcagaaaaccatgagatcgtct catcttaataga tgcagaacgattgtttatgtgttcaacatctatttgtgtgtggtttttttttcagcctcagaaaaatagtaatagataga atcggtaaagtttttttgtttgttttgagacggagtctcactctgttgcccagcctggaatgcagtggtgcgatctcagc tcactgcatcctccatctcctggagtcaagagattctcttgcctcagcctcccaagtagctgggaccacaagcgcacgcc accaggcccagctaatttttgtatttttaatagagatggggtttcaccatgttggccaggctggtctcgaactcctgacc tcatgtgatccacccgcctcagtctcccaaagtgctgggattacaggggtgagacaccacgcctggccataagttattgg cttgataaatgccattaatctacagcaaaaaccttactaaaagaagaaaatgtagacattcaccgcaaaatcaggaacaa ggcaaggatgcccactgttacaatgccagcacaattctagatatccagatcacacaatttacaaaagaaatgtgagatat aaacactggaaggaaaaagacacactcttatttaaaaagatgatatcgtcatctacaaaaaaccaatgaaaccaacagaa actaataaaactactcagaggagtaacaagttataagagcaacctacaaaaatcagatgttatcctcattaacaataacc aaatagaaaccaatatggactataagatgttacaatagcaactaaaaccattaagtagctaataattagcctcccacaaa gacacatcagacccacaaaggaaaaattttagttctatcaaagaaactaaaaagaggtgtgatcaaatgggggagattta gcatcaccatggactggacaacttaatgttataaatatgctgatttttcatggaacaatttaaattcagtacaattcgaa tcaaaattaaagtatgattttttccagaaattcaacaaaataattctgaagttttagctgagtatatttgaaaaggaata ataaagtgagaggggagagggagctctctctcattctctctctcttcctctcactggctctctctctttctctccaccag atagtaagacccattggtaagccacagtaacaaaagcagaaaaaatgcaaatacaccaatgaaataaaatagctcagaaa ctggtccacttggatatatacaaacttggtgtagaattggcttcacatatggcagaaaaaatatactttttttattgtaa ggtaaattgcctcactgtaaaggggataaaatgctaaagccaaatctatatctgactttctaggtagagcacatataaat agatgaggaaggggatcttcaaatcttattttaggaaataattatgatttgggtgtgaagaagggcatctttgaaatatc tcaaaactacaaaccaacaaggtgaggcttgtggatttgaccttatcaatatcaaggatttttgatcaacagagactacc gttgtcagatttttgactgagaagaggttttactaaagtttaaaatcagcaatagtttgatacctagatagaaggaactt ctgtccttgaatcaaaatcatgcagaaacaaggtgtgaaactcaatttaaaaagtagtcaaatgtcacaaaataagaaag ggaagcccaaacggctagcaaatatgttgaaatgatcaaactcaccagctgtcagagaaatgaaaattaaaaataaaacg aactatctattgcattacaaccatcattcggacaaaaagtatgaaagtcaaaaatacttctaactgaagttgtggggaaa ttagaacacttgcagagtgtcattccagacagcagcttggtgatcctgggtgcatgtggggtctgtctctggtggccctg- ggtgcatgtggaggtctgtttctggtggcctctgatgaatgcggggtctgtctctgatggtcctaggtgaatgtgggtgt tgtctctttctctggtggtcctgggtggatgtggggtgtgtctctgatggtcctgagtgaatgtgggtgtctgtcacttt ctctagtggccctgggtggaatatagtagccctgtctctattggtcttgcatgaaatgtagtgagcttatgtccactagt cctgggtgcagtgtgtttagcctctacatactcatcaactgctttattataagtccaggagggacgctgtccagcaggta agtaaggaacacaggtgaaggtatcagtcgtgtggctgcatgtggtagaggaaaagagagcacaacctctgtccatcact atggtgacagagaagtaaaaggtggatgtattccacggaacactcctcaactgttaggacccctgagctagacatgtata caacaataccgataaacctctaaaacaaaatgctgagcagaaaacccaagtagcaggatttctaatgctcactaaaacct ctatgaacccagaaaccggaaacacaaaccagcacaatctgttctgcatgagcacatgtgtcttggaggactggaggacg cattgccaagcacctaggcatgggtgtctatgaggggaagagaaaggcagtaggcacaggaggtttgaagaaaactgatc atttaaaatatgaaagatcataaaatcagagctgtgccctgtaggaatcttgaaaatggtctgccatgaacttaggaatc taattagctcaaaggtcagagtcatgatcaagtaagataaaaggggtcagtacccacggctcattaccctgctcttacca aacactgtgctctctctgataaaagccacgtctccagccccgtctctcagacacctgtgaaaagagaaaccatcaggggt aagcacaggcagccctccccagcccctccctgtggaacagtagccctggcactcagcatctatgggtttctactccctgc agggcagggctctgaagctt (SEQ ID NO: 12209) cctctttcaccctgtctaggttgccagcaaatcccacgggcctcctgacgctgcccctggggccacaggtccctcgagtg ctggaaggatgaaggattcctgcatcactgtgatggccatggcgctgctgtctgggttctttttcttcgcgccggcctcg agctacaacctggacgtgcggggcgcgcggagcttctccccaccgcgcgccgggaggcactttggataccgcgtcctgca ggtcggaaacggggtcatcgtgggagctccaggggaggggaacagcacaggaagcctctatcagtgccagtcgggcacag gacactgcctgccagtcaccctgagaggttccaactatacctccaagtacttgggaatgaccttggcaacagaccccaca gatggaagcattttggcctgtgaccctgggctgtctcgaacgtgtgaccagaacacctatctgagtggcctgtgttacct cttccgccagaatctgcagggtcccatgctgcaggggcgccctggttttcaggaatgtatcaagggcaacgtagacctgg tatttctgtttgatggttcgatgagcttgcagccagatgaatttcagaaaattctggacttcatgaaggatgtgatgaag aaactcagcaacacttcgtaccagtttgctgctgttcagttttccacaagctacaaaacagaatttgatttctcagatta tgttaaatggaaggaccctgatgctctgctgaagcatgtaaagcacatgttgctgttgaccaatacctttggtgccatca attatgtcgcgacagaggtgttccgggaggagctgggggcccggccagatgccaccaaagtgcttatcatcatcacggat ggggaggccactgacagtggcaacatcgatgcggccaaagacatcatccgctacatcatcgggattggaaagcattttca gaccaaggagagtcaggagaccctccacaaatttgcatcaaaacccgcgagcgagtttgtgaaaattctggacacatttg agaagctgaaagatctattcactgagctgcagaagaagatctatgtcattgagggcacaagcaaacaggacctgacttcc ttcaacatggagctgtcctccagcggcatcagtgctgacctcagcaggggccatgcagtcgtgggggcagtaggagccaa ggactgggctgggggctttcttgacctgaaggcagacctgcaggatgacacatttattgggaatgaaccattgacaccag aagtgagagcaggctatttgggttacaccgtgacctggctgccctcccggcaaaagacttcgttgctggcctcgggagcc cctcgataccagcacatgggccgagtgctgctgttccaagagccacagggcggaggacactggagccaggtccagacaat ccatgggacccagattggctcttatttcggtggggagctgtgtggcgtcgacgtggaccaagatggggagacagagctgc tgctgattggtgccccactgttctatggggagcagagaggaggccgggtgtttatctaccagagaagacagttggggttt gaagaagtctcagagctgcagggggaccccggctacccactcgggcggtttggagaagccatcactgctctgacagacat caacggcgatgggctggtagacgtggctgtgggggcccctctggaggagcagggggctgtgtacatcttcaatgggaggc acggggggcttagtccccagccaagtcagcggatagaagggacccaagtgctctcaggaattcagtggtttggacgctcc atccatggggtgaaggaccttgaaggggatggcttggcagatgtggctgtgggggctgagagccagatgatcgtgctgag ctcccggcccgtggtggatatggtcaccctgatgtccttctctccagctgagatcccagtgcatgaagtggagtgctcct attcaaccagtaacaagatgaaagaaggagttaatatcacaatctgtttccagatcaagtctctctacccccagttccaa ggccgcctggttgccaatctcacttacactctgcagctggatggccaccggaccagaagacgggggttgttcccaggagg gagacatgaactcagaaggaatatagctgtcaccaccagcatgtcatgcactgacttctcatttcatttcccggtatgtg ttcaagacctcatctcccccatcaatgtttccctgaatttctctctttgggaggaggaagggacaccgagggaccaaagg gcgcagggcaaggacataccgcccatcctgagaccctccctgcactcggaaacctgggagatcccttttgagaagaactg tggggaggacaagaagtgtgaggcaaacttgagagtgtccttctctcctgcaagatccagagccctgcgtctaactgctt ttgccagcctctctgtggagctgagcctgagtaacttggaagaagatgcttactgggtccagctggacctgcacttcccc ccgggactctccttccgcaaggtggagatgctgaagccccatagccagatacctgtgagctgcgaggagcttcctgaaga gtccaggcttctgtccagggcattatcttgcaatgtgagctctcccatcttcaaagcaggccactcggttgctctgcaga tgatgtttaatacactggtaaacagctcctggggggactcggttgaattgcacgccaatgtgacctgtaacaatgaggac tcagacctcctggaggacaactcagccactaccatcatccccatcctgtaccccatcaacatcctcatccaggaccaaga agactccacactctatgtcagtttcacccccaaaggccccaagatccaccaagtcaagcacatgtaccaggtgaggatcc agccttccatccacgaccacaacatacccaccctggaggctgtggttggggtgccacagcctcccagcgaggggcccatc acacaccagtggagcgtgcagatggagcctcccgtgccctgccactatgaggatctggagaggctcccggatgcagctga gccttgtctccccggagccctgttccgctgccctgttgtcttcaggcaggagatcctcgtccaagtgatcgggactctgg agctggtgggagagatcgaggcctcttccatgttcagcctctgcagctccctctccatctccttcaacagcagcaagcat ttccacctctatggcagcaacgcctccctggcccaggttgtcatgaaggttgacgtggtgtatgagaagcagatgctcta cctctacgtgctgagcggcatcggggggctgctgctgctgctgctcattttcatagtgctgtacaaggttggtttcttca aacggaacctgaaggagaagatggaggctggcagaggtgtcccgaatggaatccctgcagaagactctgagcagctggca tctgggcaagaggctggggatcccggctgcctgaagcccctccatgagaaggactctgagagtggtggtggcaaggactg agtccaggcctgtgaggtgcagagtgcccagaactggactcaggatgcccagggccactctgcctctgcctgcattctgc cgtgtgccctcgggcgagtcactgcctctccctggccctcagtttccctatctcgaacatggaactcattcctgaatgtc tcctttgcaggctcatagggaagacctgctgagggaccagccaagagggctgcaaaagtgagggcttgtcattaccagac ggttcaccagcctctcttggttccttccttggaagagaatgtctgatctaaatgtggagaaactgtagtctcaggaccta gggatgttctggccctcacccctgccctgggatgtccacagatgcctccaccccccagaacctgtccttgcacactcccc tgcactggagtccagtctcttctgctggcagaaagcaaatgtgacctgtgtcactacgtgactgtggcacacgccttgtt cttggccaaagaccaaattccttggcatgccttccagcaccctgcaaaatgagaccctcgtggccttccccagcctcttc tagagccgtgatgcctccctgttgaagctctggtgacaccagcctttctcccaggccaggctccttcctgtcttcctgca ttcacccagacagctccctctgcctgaaccttccatctcgcccacccctccttccttgaccagcagatcccagctcacgt cacacacttggttgggtcctcacatctttcacacttccaccaccctgcactactccctcaaagcacacgtcatgtttctt catccggcagcctggatgttttttccctgtttaatgattgacgtacttagcagctatctctcagtgaactgtgagggtaa aggctatacttgtcttgttcaccttgggatgacgccgcatgatatgtcagggcgtgggacatctagtaggtgcttgacat aatttcactgaattaatgacagagccagtgggaagatacagaaaaagagggccggggctgggcgcggtggttcacgcctg taatcccagcactttgggaggccaaggagggtggatcacctgaggtcaggagttagaggccagcctggcgaaaccccatc tctactaaaaatacaaaatccaggcgtggtggcacacacctgtagtcccagctactcaggaggttgaggtaggagaattg cttgaacctgggaggtggaggttgcagtgagccaagattgcgccattgcactccagcctgggcaacacagcgagactccg tctcaaggaaaaaataaaaataaaaagcgggcacgggcccggacatccccacccttggaggctgtcttctcaggctctgc cctgccctagctccacaccctctcccaggacccatcacgcctgtgcagtggcccccacagaaagactgagctcaaggtgg gaaccacgtctgctaacttggagccccagtgccaagcacagtgcctgcatgtatttatccaataaatgtgaaattctgtc caaaaaaaaaaaa (SEQ ID NO: 12210) ggatccagaagggtcattcaatcagttctcagtcttatcaggtctaagttcctttcttatcaggtcctaaaggcctaatc tta cattgtgacaaagataactgtagagtctgttaaactttttttttaataacatgaagattatgatttatagctgaat ttctcccttttattccaattcaacaattttcatggctttttgtgtttgttttgttctggacatatttacagaaaattacc tgaagagttccaacctgaggcctcctcatggatgggtcaaacgtgacatcatttgttgttgaggaacccacgaacatctc aactggcaggaacgcctcagtcgggaatgcacatcggcaaatccccatcgtgcactgggtcattatgagcatctccccag tggggtttgttgagaatgggattctcctctggttcctgtgcttccggatgagaagaaatcccttcactgtctacatcacc cacctgtctatcgcagacatctcactgctcttctgtattttcatcttgtctatcgactatgctttagattatgagctttc ttctggccattactacacaattgtcacatta cagtgacttttctgtttggctacaacacgggcctctatctgctgacgg ccattagtgtggagaggtgcctgtcagtcctttaccccatctggtaccgatgccatcgccccaagtaccagtcggcattg gtctgtgcccttctgtgggctctttcttgcttggtgaccaccatggagtatgtcatgtgcatcgacagagaagaagagag tcactctcggaatgactgccgagcagtcatcatctttatagccatcctgagcttcctggtcttcacgcccctcatgctgg tgtccagcaccatcttggtcgtgaagatccggaagaacacgtgggcttcccattcctccaagctttacatagtcatcatg gtcaccatcattatattcctcatcttcgctatgcccatgagactcctttacctgctgtactatgagtattggtcgacctt tgggaacctacaccacatttccctgctcttctccacaatcaacagtagcgccaaccctttcatttacttctttgtgggaa gcagtaagaagaagagattcaaggagtccttaaaagttgttctgaccagggctttcaaagatgaaatgcaacctcggcgc cagaaagacaattgtaatacggtcacagttgagactgtcgtctaagaactgtgagggaagttgtggataaaaatggtgga acacaggtcatttttagtttgtgcttggaatatgacttaagtatctcctaaatgtgatacagaagaacatctcatcccat atgcatgagatactaattaatgatgaaa (SEQ ID NO: 12211) gagcagtgcccagcttgtcgcagatattgaagccgtgtaaaataaatgcctttgattgttcacactttaagcaatattgg tacaatattaaacccattgtcccaggcactccctctccttactgcttatggcacttcatgtat aaaaaatgacagtggc agcattgcccagacatgcgttttgtcatcaagtcttaatgcagtccacctggtccctcaggcaaatgaatggaggcacag aagatgaaatgattttcaaaatgccattaggaaagctcaggccagaactggaaatgggtcccgcacagggcactcggcca ctcttgcctggccatctcctttttggcactaagcacacaatgatatagaatgaatggttatcactggggatcc (SEQ ID NO: 12212) ggatccagaagggtcattcaatcagttctcagtcttatcaggtctaagttcctttcttatcaggtcctaaaggcctaatc ttatcattgtgacaaagataactgtagagtctgttaaactttttttttaataacatgaagattatgatttatagctgaat ttctcccttttattccaattcaacaattttcatggctttttgtgtttgttttgttctggacatatttacagaaaattacc tgaagagttccaacctgaggcctcctcatggatgggtcaaacgtgacatcatttgttgttgaggaacccacgaacatctc aactggcaggaacgcctcagtcgggaatgcacatcggcaaatccccatcgtgcactgggtcattatgagcatctccccag tggggtttgttgagaatgggattctcctctggttcctgtgcttccggatgagaagaaatcccttcactgtctacatcacc cacctgtctatcgcagacatctcactgctcttctgtattttcatcttgtctatcgactatgctttagattatgagctttc ttctggccattactacacaattgtcacattatcagtgacttttctgtttggctacaacacgggcctctatctgctgacgg ccattagtgtggagaggtgcctgtcagtcctttaccccatctggtaccgatgccatcgccccaagtaccagtcggcattg gtctgtgcccttctgtgggctctttcttgcttggtgaccaccatggagtatgtcatgtgcatcgacagagaagaagagag tcactctcggaatgactgccgagcagtcatcatctttatagccatcctgagcttcctggtcttcacgcccctcatgctgg tgtccagcaccatcttggtcgtgaagatccggaagaacacgtgggcttcccattcctccaagctttacatag catcatg gtcaccatcattatattcctcatcttcgctatgcccatgagactcctttacctgctgtactatgagtattggtcgacctt tgggaacctacaccacatttccctgctcttctccacaatcaacagtagcgccaaccctttcatttacttctttgtgggaa gcagtaagaagaagagattcaaggagtccttaaaagttgttctgaccagggctttcaaagatgaaatgcaacctcggcgc cagaaagacaattgtaatacggtcacagttgagactgtcgtctaagaactgtgagggaagttgtggataaaaatggtgga acacaggtcatttttagtttgtgcttggaatatgacttaagtatctcctaaatgtgatacagaagaacatctcatcccat atgcatgagatactaattaatgatgaaa (SEQ ID NO: 12213) ggatccagaagggtcattcaatcagttctcagtcttatcaggtctaagttcctttcttatcaggtcctaaaggcctaatc tt tcattgtgacaaagataactgtagagtctgttaaactttttttttaataacatgaagattatgatttatagctgaat ttctcccttttattccaattcaacaattttcatggctttttgtgtttgttttgttctggacatatttacagaaaattacc tgaagagttccaacctgaggcctcctcatggatgggtcaaacgtgacatcatttgttgttgaggaacccacgaacatctc aactggcaggaacgcctcagtcgggaatgcacatcggcaaatccccatcgtgcactgggtcattatgagcatctccccag tggggtttgttgagaatgggattctcctctggttcctgtgcttccggatgagaagaaatcccttcactgtctacatcacc cacctgtctatcgcagacatctcactgctcttctgtattttcatcttgtct tcgactatgctttagattatgagctttc ttctggccattactacacaattgtcacattatcagtgacttttctgtttggctacaacacgggcctctatctgctgacgg ccattagtgtggagaggtgcctgtcagtcctttaccccatctggtaccgatgccatcgccccaagtaccagtcggcattg gtctgtgcccttctgtgggctctttcttgcttggtgaccaccatggagtatgtcatgtgcatcgacagagaagaagagag tcactctcggaatgactgccgagcagtcatcatctttatagccatcctgagcttcctggtcttcacgcccctcatgctgg tgtccagcaccatcttggtcgtgaagatccggaagaacacgtgggcttcccattcctccaagctttacatagtcatcatg gtcaccatcattatattcctcatcttcgctatgcccatgagactcctttacctgctgtactatgagtattggtcgacctt tgggaacctacaccacatttccctgctcttctccacaatcaacagtagcgccaaccctttcatttacttctttgtgggaa gcagtaagaagaagagattcaaggagtccttaaaagttgttctgaccagggctttcaaagatgaaatgcaacctcggcgc cagaaagacaattgtaatacggtcacagttgagactgtcgtctaagaactgtgagggaagttgtggataaaaatggtgga acacaggtcatttttagtttgtgcttggaatatgacttaagtatctcctaaatgtgatacagaagaacatctcatcccat atgcatgagatactaattaatgatgaaagagcagtgcccagcttgtcgcagatattgaagccgtgtaaaataaatgcctt tgattgttcacactttaagcaatattggtacaatattaaacccattgtcccaggcactccctctccttactgcttatggc acttcatgtattaaaaaatgacagtggcagcattgcccagacatgcgttttgtcatcaagtcttaatgcagtccacctgg tccctcaggcaaatgaatggaggcacagaagatgaaatgattttcaaaatgccattaggaaagctcaggccagaactgga aatgggtcccgcacagggcactcggccactcttgcctggccatctcctttttggcactaagcacacaatgatatagaatg aatggttatcactggggatccggatccagaagggtcattcaatcagttctcagtcttatcaggtctaagttcctttctta tcaggtcctaaaggcctaatcttatcattgtgacaaagataactgtagagtctgttaaactttttttttaataacatgaa gattatgatttatagctgaatttctcccttttattccaattcaacaattttcatggctttttgtgtttgttttgttctgg acatatttacagaaaattacctgaagagttccaacctgaggcctcctcatggatgggtcaaacgtgacatcatttgttgt tgaggaacccacgaacatctcaactggcaggaacgcctcagtcgggaatgcacatcggcaaatccccatcgtgcactggg tcattatgagcatctccccagtggggtttgttgagaatgggattctcctctggttcctgtgcttccggatgagaagaaat cccttcactgtctacatcacccacctgtctatcgcagacatctcactgctcttctgtattttcatcttgtctatcgacta tgctttagattatgagctttcttctggccattactacacaattgtcacattatcagtgacttttctgtttggctacaaca cgggcctctatctgctgacggccattagtgtggagaggtgcctgtcagtcctttaccccatctggtaccgatgccatcgc cccaagtaccagtcggcattggtctgtgcccttctgtgggctctttcttgcttggtgaccaccatggagtatgtcatgtg catcgacagagaagaagagagtcactctcggaatgactgccgagcagtcatcatctttatagccatcctgagcttcctgg tcttcacgcccctcatgctggtgtccagcaccatcttggtcgtgaagatccggaagaacacgtgggcttcccattcctcc aagctttacatagtcatcatggtcaccatcattatattcctcatcttcgctatgcccatgagactcctttacctgctgta ctatgagtattggtcgacctttgggaacctacaccacatttccctgctcttctccacaatcaacagtagcgccaaccctt tcatttacttctttgtgggaagcagtaagaagaagagattcaaggagtccttaaaagttgttctgaccagggctttcaaa gatgaaatgcaacctcggcgccagaaagacaattgtaatacggtcacagttgagactgtcgtctaagaactgtgagggaa gttgtggataaaaatggtggaacacaggtcatttttagtttgtgcttggaatatgacttaagtatctcctaaatgtgata cagaagaacatctcatcccatatgcatgagatactaattaatgatgaaa (SEQ ID N0:12214) gggcccagagaaagagctgtccccggggccttggggacagggtgacagccacccagagatcatggagaaggggacgtaag gaagacctcacagaggagtcatcctgcgactgtgttggttgggtccttcaggaagcagagtcccaggagttggaagcata agaggaatactgcgggcaatgcctgagaaagataacagggaccgggagcaggagtgagttgggcaggggaaggatcaggc ccacaatgccaggctcacacctgcagaggagggaagaagaagaagggcctcacatcagcccagcgggggatgttacgccc acagacgccccggggctcagttactgtctaagtgttagaaataaattttcggtgccacaaaagaaatagcactcagatta aatgttcccagcaaggcaattttacttctatagaagggtgcatctcacagatggagcaatggcaagagcacacctgaaca agggaagggaaggggtttttatccctaaggcaggtagcccctacagctgtgttgttcccctattggctagggttggacca caccgtctgagctaattgttactggctattttaaagagagcaggggtaagagccggattggcagggtaagtagtttggca ggaaggacggtcacagaacaggtgactcaggatgactcaggtcagagcaggtgaccagtggtgactcagttcggagcagg tgatagaagctaggagggggttgtttactgaaactaggggcaaggagacgaagagaacatgaaagttaaactttaagatg aagaacaaagctgaacatactgatgcattggatctttggagaggatctcagaactcattgtacttaatttacaggctaaa accttagaagaggaatttattatatcctacacaagactccagggaagcacatggccttggactgaaggctggcatctgga agctgtcagccaccagcaccttctgcagcaggtacctgctctctaagagggaggcctgggtggtgcacctccagagctgc ccaggctgggcctcaaggaagaaaaagattttcatttgtcagaggcggaagggagaggtggagggaacagcacagcagcg gcccaggggcagggaagcacaggaccattagggagacacgagaaagcccatttgtctagaacagaggattcaagcagtgc accaaggaaaatgagggccaggccaatgtgctggagtggctttgttcttggctgagggttttgggtagtgccaaagcgta aggtaagccctgctttccagaagaatctagcagagtgtggagcccagatgggactggaaggcctgggaggggtcaggtgg ccacagggacgggccacagccagtggtgcaggcaagaagacaatggccatccatggtggctcacacctggaatcccagcc cattgggaggtcgaggcaggtggatcacctgaggtcaggagttcgagaccagcctggtcaacatggtgaaaccctgtctc taataaaattataaaaattagccgggcgtggtggtgggtacctgtaatctcagctactcaggaggctgggtcaggagaat cgcttgaacccaggaggcggaggttacagtgagctgagatagcaccattgcattccagcctggacaacaaaagcgagact ctgtctcaaaaaaaaaaaaaaattagccaggcgtggtggtgggtgcctgtcgtcctcgggaggctgaggcatgagaatca ctccgggaggcagaggttgcaatgaaccaagatcacaccactgcactccagcctgggtgacagagcaagactctgtctaa aaaaaaaaaaaagacagaaggatgtcagcatctgatgctgcctgtcaccttgaccctgaggatgccagtcacagctccat taactgggacctaggaaaatgagtcatccttggtcatgcacatttcaaatggtggcttaatatggaagccacacttggga tctgttgtctcctccagcatggtagaagatgcctgaaaagtaggggctggatcccatcccctgcctcactgggaaggcga ggtggtggggtggggtggggcctcaggcttggggtcatgggacaaagcccaggctgaatgccgcccttccatctccctcc tcctgagacaggggcagcagggcacactagtgtccaggagcagcttatgaggccccttcaccctccgatcctccaaaact ggcagaccccaccttcttcggtgtgaccccagagctctgagcacagcccgttccttccgcctgccggccccccacccagg cccaccccaaccttatcctccactgcttttcagaggagtctggccaacacaaatcctcttgtttgtttgtctgtctgtct gctgctcctagtctctgcctctcccagtctctcagcttccgtttctttcttaaactttctctcagtctctgaggtctcga aatcacgaggcttcgacccctgtggaccagatgcccagctagtggcctttctccagcccctcagatggcacagaactaca aaccccagcatgcactctggcctgaagtgcctggagagtgctggtgtaccccacctgcattctgggaactgtagtttccc tagtcccccatgctcccaccagggcatcaagctcttccctggccggctgaccctgcctcagccctagtctctctgctgac ctgcggccccgggaagcgtgcgtcactgaatgacagggtgggggtggaggcactggaaggcagcttcctgctcttttgtg tcccccacttgagtcatgggggtgtgggggttccaggaaattggggctgggaggggaagggataccctaatgtcagactc aaggacaaaaagtcactacatccttgctgggcctctatccccaagaacccaaaaggactcaagggtggggatccaggagt tcttgtatgtatggggggaggtgaaggagagaacctgcatgaccctagaggtccctgtggtcactgagagtgtgggctgc catcccctgctacagaaacggtgctcaccttctgcccaaccctccagggaaaggcacacaggggtgaggccgaaccttcc gtctggtgccacatcacagaaggacctttatgaccccctggtggctctaccctgccactccccaatgccccagcccccat gctgcagccccagggctctgctggacacctgggctcccacttatcagcctcagtcctcacagcggaacccaggcgtccgg ccccccacccttcaggccagcgggcgtggagctgaggctttagagcctcccagccgggcttgttcctgtcccattgtgta tgggataggggcggggcgagggccagcactggagagccccctcccactgccccctcctctcggtcccctccctcttccta aggaaaaggccagggctctgctggagcaggcagcagagtggacgcacagtaacatgggcaacttgaagagcgtggcccag gagcctgggccaccctgcggcctggggctggggctgggccttgggctgtgcggcaagcagggccc (SEQ ID NO:12215) ggatcccatgccctgcctcactgggaaggcgaggtggtggggtggggtggggcctcaggcttggggtcatgggacaaagc ccaggctgaatgccgcccttccatctccctcctcctgagacaggggcagcagggcacactagtgtgcaggagcagcttat gaggccccttcaccctccatcctccaaaactggcagaccccaccttcttggtgtgaccccagagctctgagcacagcccg ttccttccgcctgccggccccccacccaggcccaccccaaccttatcctccactgcttttcagaggagtctggccaacac aaatcctcttgtttgtttgtctgtctgtctgctgctcctagtctctgcctctcccagtctctgagcttccgtttctttct taaactttctctcagtctctgaggtctcgaaatcacgaggcttcgacccctgtggaccagatgcccagctagtggccttt ctccagcccctcagatgacacagaactacaaaccccagcatgcactctggcctgaagtgcctggagagtgctggtgtacc ccacctgcattctgggaactgtagtttccctagtcccccatgctcccaccagggcatcaagctcttccctggctggctga ccctgcctcagccctagtctctctgctgactgcggccccgggaagcgtgcgtcactgaatgacagggtgggggtggaggc actggaaggcagcttcctgctcttttgtgtcccccacttgagtcatgggggtgtgggggttccaggaaattggggctggg aggggaagggataccctaatgtcagactcaaggacaaaaagtcactacatccttgctgggcctctatccccaagaaccca aaaggactcaagggtggggatccaggagttcttgtatgtatggggggaggtgaaggagagaacctgcatgaccctagagg tccctgtggtcactgagagtgtgggctgccatcccctgctacagaaacggtgctcaccttctgcccaaccctccagggaa aggcacacaggggtgagccgaaggcccttccgtctggtgccacatcacagaaggacctttatgaccccctggtggctcta ccctgccactccccaatgccccagcccccatgctgcagccccagggctctgctggacacctgggctcccacttatcagcc tcagtcctcacagcggaacccaggcgtccggccccccacccttcaggccagcgggcgtggagctgaggctttagagcctc ccagccgggcttgttcctgtcccattgtgtatgggataggggcggggcgagggccagcactggagagccccctcccactg ccccctcctctcggtcccctccctcttcctaaggaaaaggccagggctctgctggagcaggcagcagagtggacgcacag taacatgggcaacttgaagagcgtggcccaggagcctgggccaccctgcggcctggggctggggctgggccttgggctgt gcggcaagcagggcccagccaccccggcccctgagcccagccgggccccagcatccctactcccaccagcgccagaacac aggtaagggccaggcagctaggagcaggtgggcaacaagggtggtgtcaaggcctgaagcctggggctgggaaggtctgg aacttgtagctgagtcgggagggccaggtcacaaatgcaaaagggctattaatgtgcatagaacaggacagtctgggagg ctcagaaaggagaccaggatcagagtcggcaggtgaagctgggagtaagggtgccagctatagaatctggccagggtttg aatgctgctctgccgccaggagctgtttgactttgagcaagttacttaatctctctgaacctccatttatataaaacgag atatggcaatacttactccatggggaagtaagtttctagctcacagcaagccttcaacagcagcgatgattatttagctg gagaagaaaggagctgacagcagtggttacaggagtgagaaagtggggtctcccagaagagggagagagttgggcaggaa actcgggcccttggggtaagcaggctgagaagacagagccaccaggcttttttcccctgctccagccccctctcctcgtg gctgtcacccgaaaactggaccatgcagttcccacaagagtcctcccgggggtagaggtcccaggagggaggaaagaccc ggaggcctggtggggtgccaggccgggggcaggctggggctgcaggcagctatgcagggaaggctgagggccggggccct gctgctcaggcgcacccttggcctgagtccctcccttcctccctgccgctggtggctctgggaggaagtgataaggcctg cgaggcttcccttcacacatggggctgctgtcaggaggggttgtgagtgcggagggaaatcagagctgaggaatccctgc agggcttccctccactcaagcaccaggctctgtccccctcagggtagggcttatagcagctttgcggggggtggacaccc catctccagaagaggtgaggtgggcgctgcaggtgggatgcgaacttagcctcgggtcaggggctcaggagctcagcacc agcagcccctgcagcccaggaccctggtctataaacggaggcacagctcgcctctagctcctaaggcatggggaacgcca gaaggcatgcggcaggtgggctgtgagatcgccagtgctgtaacaggggcctccgggtgacatctgggaaggctgaaagg aaacaaacccttcctgatgaccctatccctggctcccaacagccccccgagctccccgctaacccagcccccagaggggc ccaagttccctcgtgtgaagaactgggaggtggggagcatcacctatgacaccctcagcgcccaggcgcagcaggtaagg ccggcatgccctgtccccatcgtctccagggaaagggtgggtaaggcctggcctcagatggggccggagagggaagctca acccttctttgaattggtcccttgtttccaaaaagaggagaggactgggaagaaccagaggagttgagggacatgcacgg gacttgggtgaccctcagcctccagccttacccccaaccctggctcaaacttttcccccatcccacccctgcaccccttt tccccctcccacccctgcacccttcctccctctcccccaccccacccctgccccccctcccatcccagctctaaacccct cctccctctcccccgtcccacccctaaaccccacctccctgtccccctctaaacccctcctccctgtccccctctaaacc ccacctccctctccccatcccacccctgcacccttcctccctctgcccccgtcccacgcctgtactcctcctccctctcc cccgtcacacccctgcacccctcctccctctccccatcccatccctgcacccctcctccctctgcccccgtcccacccct aaacccctcctccctctgccccaccccacccttgcacccctcctccctcttcccccgtcccctgcctgcattcctcctcc ctctccccatctcacccctgcacccctcttccctctcccacccctgcacccctcctccctctccccgtcccaccctgcac tcccgccctctccagcgtcccacccctacacccctcctccctctgccccattccacccctgcaccccctcctccctctgc cccgacccacccctgcacccctcctccctctcccccgtcccacccctgcatccctcctccctctgccccgtcccacccct acacccctcctccctctcccccatcccacccctaaacccctcctccctctcccctgtcccatccctgcacccttcctccc tctccccgtcccatccctgcacccttcctccctctccccgtcccatccctgcacccctcctccctctgctcccatcccac ccctgcacccctcctccctctgcccctaccccacctctgcacccctcctccttctccccatcccacccctgcacccctcc tccctctgcccctaccccacccctgcacccctcctccttctccccatcccacctctgcacccctcctccctctcccctct cccacccctgtacccttcctccttctccccgtcccacccctgcacttctcctccctctaacccatcccacccctgcaccc ttcttccctctcccccatcccaccactgcacccctcctccctctccccctgttccacccctgcacccctcctccctgccc ccaactcccatcccacccctgcaccctggcctgtcctgacctttgcactccctcgacccaggatgggccctgcaccccaa gacgctgcctgggctccctggtatttccacggaaactacagggccggccctcccccggccccccggcccctgagcagctg ctgagtcaggcccgggacttcatcaaccagtactacagctccattaagaggtgacagcttcccggacgccacagcctccc ttgtcccactgaggccccagaaaccccgtgacgaccttcccatgaccccctcccttcccagatcctaacaccacgtgggc ccctcccgccctcccccagcacttgcacaaagcctggaggagggcctccctgtcccacacaacttcctgcttgtcccctt cccacccctctcctccccaggagcggctcccaggcccacgaacagcggcttcaagaggtggaagccgaggtggcagccac aggcacctaccagcttagggagagcgagctggtgttcggggctaagcaggcctggcgcaacgctccccgctgcgtgggcc ggatccagtgggggaagctgcaggtgcggctggccagcgactgagagacccgggcgctaccaaaaggggagcggggtggc ggggcagttcctaaggcttcccgggggctgggaggtcccaaactgtgggggagatccttgccttttcccttagagactgg aaaggtagggggactgccccaccctcagcacccaggggaacctcagcccagtagtgaagacctggttatcaggccctatg gtagtgccttggctggaggaggggaaagaagtctagacctgctgcaggggtgaggaagtctagacctgctgcaggggtga ggaagtctagacctgctgcaggggtgaggaagtctagacctgctgcgggggtgaggaagtctagacctgctgcgggggtg aggacagctgagcggagttccctgggcggtgctgtcagtagcaggagcagcctcctggaaaagccctggctgctgcttct cccccaagagagaaggcttctcccgccaggccagtccagtgcagcccctcacccacacccactgctaccccagttcccct gcttcggcccgcaccctccctcacaccccagcccacagactcggggctggccttagttactggaacgcctgtgaccacag cactaagagaagcaagctgccccatgggggacttggtccccatggccttggcctccttcaccatcactggccgccaaaga gtttgaaataaagccacgtgcccagtgaatcccaaaggaacctcaactaaaataaaaacaatcctatctgacacttgcct gaccctctaagtcattcaaagctttagctcaacttcgatccatctgagctgccatagtggaccccactcagagctgcgtc cctcccttgaccccaggttggtccctgccactcccctgcccctgtcactgacacatgtttcctcctccctcaggcaggag tgggacctcccagcctcctcctggggcctccactcagaatgtcaggatgagcagggtcctaggaggcctctggtgcagcc ttcccttcccaccatccatgtgctcaaagagaatcacccgtcctttcttgaatgccatggatcatgggggatttgctgcc cacactcctaggcggcctcttagacatccgttggtgcctaacccaagcatcagtttggcagaggccgagtccctcctctg tactggataccaagtcagcttccatagggatggggagacacctggcccagggaggagatgagaagcagcccggatggtgc tacatatgtcagagagcagggcaggaagggatcagtgtggctgccaatggtcaggagggcgccatggagtgaaccatggc ccctgcctcctcaaccaagaagtcctctggagctgatactcaagaccccccgtctctctcctcaccctcctctcccgctg cctcggctggctcaggtgttcgatgcccgggactgcaggtctgcacaggaaatgttcacctacatctgcaaccacatcaa gtatgccaccaaccggggcaaccttcggtgagtgccccccaccatgccaggccccagccttcttccccaaggcagggaag gcggggctctgaccagctctttccccatgcgtgccagctcggccatcacagtgttcccgcagcgctgccctggccgagga gacttccgaatctggaacagccagctggtgcgctacgcgggctaccggcagcaggacggctctgtgcggggggacccagc caacgtggagatcaccgaggtgggcaccgagggccacccatgagggtgtccccaaggtggagaatgaggaaaccagtggg agaaggctcgggggatccaggcaggaagaggggagcctcggtgagataaaggatgaaaaacaccaaaggaggggtgcctg ggtggtcacggagacccagccaatgagggaccctggagatgaaggcaggagacagtggatggaggggtccctgaggaggg catgaggctcagccccagaaccccctctggcccactccccacagctctgcattcagcacggctggaccccaggaaacggt cgcttcgacgtgctgcccctgctgctgcaggccccagatgagcccccagaactcttccttctgccccccgagctggtcct tgaggtgcccctggagcaccccacgtgagcaccaaagggattgactgggtgggatggagggggccatccctgagcctctc aagaagggcctgcaagggggtgctgatcccacaccccaacacccccaggctggagtggtttgcagccctgggcctgcgct ggtacgccctcccggcagtgtccaacatgctgctggaaattgggggcctggagttccccgcagcccccttcagtggctgg tacatgagcactgagatcggcacgaggaacctgtgtgaccctcaccgctacaacatcctggaggtgaggtgcgggatggg gctcgggcaccgaatgcacctgtccaaggcaggagtctggctctcactccatccccaaaatgccagccacggggacaatc agagcaggtccagggttgcctcctaaatgggaactgaggacaagctctagaaccactgaagcaaaggggtagggggtggc aggggtgtgtgtgggggtgtgagtgggtgagtgtgagagtgtgggtttctggggtgtgcagtgggtgagagtgtgggctt gtggggtgtgtagtgggtgtgagactgtgggtttgtaggggtgggtgagtgtgggtgtgtgggggtaggtgggtgtgggt ttgtgggtgtgtataggcagtgactgtgagactgtgggtttgtgggggtaggtgactgtgggtttgtggggtgtgtaggg gtgagtgtgtgtgggtttgtaggggtaggcgagtgtgggtttgtggggtgtgtaggggtgagtgtgtgtgagtttgtagg ggtaggcgagtgtgggtttgtggggtgtgtaggggtgagtgtgtgtgagtttgtaggggtaggtgagtgtgggtttgtgg ggtgtgtagggggtgtgtgtgggcttgtaggggtaggcgagtgtgggtttgtggggtgtgtaggggcgagtgtgagagtg taggtatgtgggtgtgagtgtggatgtgtgtaggcggtgagtgtgaaattgtgggtttgtgggggtgggtgggtgtgagt gtgtgggtttgtgggtgggtgtgggtgtgagtgggtgggtgaggggggcatggggatgggtgtgaacatgtagttgttct ttcaggcataggacccatagctctagagctttcatcagattctcaaaggggaccttgactcggaaaaggttaagacccat tttagagatgagaaattaaagcctggagctgaggagcgactggcccaaagtccctctctgctctgaggtgcttcgcaggc aaaaacctgaaccagccccctaggcagccaggcctcccaatggacaccactcacctcactccttccagccatgtacggga aacagagatagtctccccaccccacccccgtgatcacctctgtccctaccgatgccacacacccttctgccccaggatgt ggctgtctgcatggacctggatacccggaccacctcgtccctgtggaaagacaaggcagcagtggaaatcaacgtggccg tgctgcacagttaccaggtgcagaggcccagactggccaggaaggcaaagggtttgcatacgggggcagcaggggcgggg gatggaggagaggcagccatttagaaactagggcaggatttggacaggcagaagaagttccgtagtcccagtgccatggc gcacactggctgcggttcggggacagggcaggtactattccaggcgctgtcatctggtggcttactgtgtgccagggacc ttgctgtttactgcatgcccagtcatgctgattctcagggcatattgggtattgcagtttgtgggacccgctggatcctg gaaacaaataccaggatcaagggcacaccaggagtcgtagtttgaggaagccggggcctgctgagaatttctgtgggcta tttggtttggggaccaggcatgcagatgctggagattagagctgcttgttgcatgttgaacctgcagcatgaccatgcat gatgtggtttggggtgagggtgacattgtggtttgaggggacacagggtgtgttagatatggggtaatcgagggcacatg tggtttggggtgaccggagtggtggaggaagaatgggcgaggtctgtgggtctggtttgagcctctccccctctctctcc cttccagctagccaaagtcaccatcgtggaccaccacgccgccacggcctctttcatgaagcacctggagaatgagcaga aggccagggggggctgccctgcagactgggcctggatcgtgccccccatctcgggcagcctcactcctgttttccatcag gagatggtcaactatttcctgtccccggccttccgctaccaggtgcccaccctaatggctctgccagcctgggcccagct ctaattctaagcagcccctggggacctctaacctttccttttctttacctcccctcccaaccccatcatctctctgcagc cagacccctggaaggggagtgccgccaagggcaccggcatcaccaggaagaagacctttaaagaagtggccaagtgggtc ccctgggagccccgctctcccacacacaccctgggggccccactctcccccacacaccctgggggaccctgccccagcag tgttctggacctaccactcagtatcccaaaaccctgttgtgagggggttggacccttgcctggggaggccctgcctctgt gcacccgggacaccctcacaccttcctctcccgcagcgccgtgaagatctccgcctcgctcatgggcacggtgatggcga agcgagtgaaggcgacaatcctgtatggctccgagaccggccgggcccagagctacgcacagcagctggggagactcttc cggaaggcttttgatccccgggtagggctgagcccaggggagcagggagctagaaagagggggctctatcagcatcttca ggggtgccctggaggacaggaagtgttacaagtcaggactcatgaggaacccggaaccacaggtgttcagagatcaagtt ggggcctgaatcttgcactgccagggaggccagagtgaggagggcagggcctccgggggccacagcacccaggacatctg tcttcccacccacaggtcctgtgtatggatgagtatgacgtggtgtccctcgaacacgagacgctggtgctggtggtaac cagcacatttgggaatggggatcccccggagaatggagaggtgagaacttccaggaaaggggctgctgggaatgaggaga gactcagaattggagtgactgggcaggaacctctgcccaacacacacacacacacacacacacacacacacacacacaca cacacacacacacacacacacacacacacacgccaggatggaaagggagatgctaagagacccctggagcctgaaacccc acacaacgtacgctcccagcccacccatgtggctgcctccctgcaagcacatttgcttaactgcgcgtccccaagtcatt tccattatcagtgcaagtttttaatacaaggaaggcacatcctggctgaccaagaggttagactgtgctcgggcactgac aagaaaaacagggatacgtcactgagggcggcttctaggatgcgggtaatgtttcttaatgggatactggttacacaggt gtgttcagtttgtaaaaatccacagagctgtacatttacaacatgtacaacactattccagcattttattttatttgttt tatttattttgataacctatttacgttgcccaggctggccttgaactcctagcctcaagagatcctcctgccgcaggctc ctttttcaaaagaagaaattgagcgctgtttagatgccaacatagattaaataacttcactttttaaaaagaaacacaaa gctagagtaccatcattgaattccttctcttgcaagcttaggtatctctgaggtgccccaggctaggctcatttctgagt cttacctgctccagcttctaggtgttaaaggccttattagcactaagtacttcctcagtactcttttttcttttttcctt tgagacagggtctcactttgtggcccaggctggagtgcagtagtacaatcacggctcactgcagcctcaacctcctagac tcaagcaatcctcccacttcaacctcccaagtagttgggactacaggcgcatgccatgatgcctagctaatttttgtatt ttttatagagatggggtttcgccatgttgcccaggctggtctctaactcctgggttcaagcaatccacctgcctcggcct cccaaagtgctgcgattatagacgtgagccactgcacctggcccgcagtatcttaagcaagttggaatctcgtgaaaccc tttttgctgccttagtgtccgtttcagccctcattcttacctaccttttcaagaaaaatagcaccagcaattgacttttt tttagcataaaggtgtatagaacccatataacctacagccttcacaaggcatagcacattttcaccaccctggaaagttc cctcatcagttcctcacgtgaatcccttcccagtctgtctccctgccagaagtgtctgtcaccacagaatagtttcgcct gctctagaacggcacctagatggaagcacgcagtgttgcggcgtctcctgctgaggctgtttttgaggcgcactcgtgtt gctgcgtgactcagtatttcactcattctgctgctgagtgccgttcattgtgtgaatatccccagtttgtttacccattc tcttgttggtgacacttgggctgtttccaggtcggggctattatgaataaacctgttatgaacattctgtacccggcttt tgtgggcttatgtttttatttctcttgggtaaaacctaggagtagaattggtaggtcatagggtagatgcatgtttaatc tttcacttttttaaaaaataaaactgccaggccaggcgcggctgctcacgcctgtgatcccagcactttgggaggcccag gtgggtggatcacttgaggtcagaagctcaagaccagcctggccaacatggcaaaaccctgtctctactaaaaatacaaa aattagctgggcatggtggcgcacgcctatagtcctagctactcaggaggctaggcgggagaattgcttgaacctgggag gtggaggttgcagtgagccgagatcacgccactgcactccagcctgggtgacagagcaagaattctacttaaaataaaat acaaataaataaaataaaactgtcaaacagcaaagcaaattaaactgccctttaacatctgtgcagttcaatgtatgtta attttatcccaaatttttaacaaatctaggaatacagctcacagaaaatggggtatattcactaaaaataaggaatattt atagcaaatttgtttgtaataccccacactggaaacaattcaaatgaccatcgacaaatactgataaattgtggtatatt caagtgccatatcgcactaagtgtgaacgaaacacaaccacacacaacagtgcaggtgaatctgaaaaaatgtgaagaga agaaaaagccagaccaaagaatacatactgtactacagggttcactt atataaagttcagaaacaggcagaactaatcc acggagttagaaattaggagaggagttagtcactgggatgggggtggcagtgacaggaagaaggcacgaagttggcttct aggatgcgggtaatgtttgtttgtttgtttgtttgtttgtttttgtttttgagctggagtctcactctgttgcccaggct ggagtgcaatggcgtgatctcggctcactgcaacctccgcctccccggttcaagcgattctcctgcctcagcctcccgag tagctgggattacaggtgcccgccaccatggccagctaatttttgtgtttttagtagagacgcgtttcaccatgttggcc aggctggtcttgaatccctgacctcagcctcccaaagtgctgggattacaggcgtgagccaccacgcccagccacgggta atgtttctcgatgggatgctggttgcacaggtgtgttcagtttgtgaaaacttacagagttgtacatttacaacatgtgt gcacctctggacttgtgttgcacgttgacaaaacattcaaaaatgaaattcaaatcgttcttgctaactctggcgcactt gggaaccagcacccagaggcatctgcagttgagcaccagatgcagttccttccagcttccttccccctgggaggtccgct tgatgccacttcttcatggcagcacaaacaaggccatggtcttctgaggagggcaacctgcacaatgtctgctagtgacc aggacactgctgaaggaactgagagtttgtccacccatgaaatccactaaaacaggaaagattttgctctagccgttgtt agccaggagtgaggaaagagctgtgccctcccctgcagctgcgaggacgatctgcctgccccaacaagtggggattcagc aactccacttctaaggattacccagctgaagcatttaaaagtgggagcaaggcacacgtacaagggcgtttgagagagca cctgttcccagaccaccgagctgcccttcagtctcagtgaagtacaatgtagccactaaaaagactgaggtcatgttttg gaaagtccaggccggaggatcgcttgagcccaggagttcaaggccagactgaacaacacagcgagactccatctcttcag aaaatttaaaaattaaccaagagtggtggcacgcacctatagatctagctactaggaaggcagaaaaatcccttaagccc aggagtttgaggttacagtgaatgatgatggagccactgcaccccaacctgggcgacagagcaagacccatatctaaaaa caatactactacttacgtcaatattgttgtattgacctggagggatgtctgcaataaattattgattaaaaccaaggaag tacagtatggtaccacttttacttaaaaaaaaactataaatatgcacgtgcacgtaagttcaaggaaaaagggctggaag gttaacacctgtgaatggcgcatatgcccggaggaagatggggtggtctttgtcttatcactttacacatttctgtaatg tcatttttcaaaaacatcagatcgcttttgaaattttcaaaacaaataaaaattaagtgacaaatcaataataatgagga tcagctggtacagttttaaacttctatgtagtttgaaatgaaacaaaactaaccctgatgcaaacactcccctcgccaga gctttgcagctgccctgatggagatgtccggcccctacaacagctcccctcggccggaacagcacaagtgagttgggtga gagtttgggggagctgggggagctgatgcatttggagacacaaacagaaagggggtctgaaaagctctccctctgtgcct caagtcgttttcccaccaaaagccagggctccaggatgccctccattccaggctgcaatggcagtccagacctgcctgct tctgagagccgggacagtcctgaggtcttcagagatgggggtgtggtgtgtcagggccccaggctcggaaccccagggat gctggccctcagcccctcccaagggcagggcctttcctgtccagaggcagagaccctgaagccgtccctggggctgggtc tgggcctagcctgtatccccagggccctgtgacaaccttgtctttgtcctctcttgccaggagttataagatccgcttca acagcatctcctgctcagacccactggtgtcctcttggcggcggaagaggaaggagtccagtaacacagacagtgcaggg gccctgggcaccctcaggtcagggcctcaccaagaggggtgcaacgggtgggcaagctgcctgggcaaacgtggcctgca aagggagctccactgacgacccctgcaccccaggttctgtgtgttcgggctcggctcccgggcatacccccacttctgcg cctttgctcgtgcggtggacacacggctggaggaactgggcggggagcggctgctgcagctgggccagggcgacgagctg tgcggccaggaggaggccttccgaggctgggcccaggctgtagttagggttaagaccaccctttggccttggtgtcaeca aggactcaaagaaggtgaaggttttggtttttttttcccccagagatggagtcttgctctgtcgcccaggctggagtgca gtggtacgatctcggcttactgcaacctccgectcccgggttcaagagattctcctatggcgtgaacctgggaggtggag cttgcagtgagccaagattgtcceactgcactccagcctgggcgacagagccagactctgtctcaaaaaaaaaaaaaaaa tattctcctgtctcagcctcctgagtagctgggattacaggcacccaccaccacgcccagctaatttttgtatttttagt agagacggtgtttcactatgttggccaggctggtctcgagctcctgacctcacaatcctcccacctccgcctcccaaagt cttgggattacaggtgtgagccaccgcgcccggaccgagggtgaaggattttaagagacccttccttcatgctgtgtcca gaagtcttgcccgctctcgcagccaggaaccaaaagtcctggtaggactgagaacagttcctaggctgccatcagctggg cctggtgattcaaatccacccaggtggctaaactacaaataaaccgtacccatctactgaacataaactaaataccacta ttaaggatacttaaaataaacacacttagtgaacccattatgaactgaaagtgtctttcacccttcccacgttttctaaa tcccctgagtcatctaagtattcttcaatccaaaatgaactatatttcctttggtgcaatctccagaaaccacagatcca aggagtttcagcaagtagagttgttttttgttttttgttttttttttaatttttttttgagatgggaagaacttgggtcc tccttgctccacccaccctgcatggtgagaatggtggagcaggaaaggcaaaggggacctgatggagtgtctctcctgcc agggctccctccttccggctgccacccgatcccagcttgccctgcatcctggtgggtccaggcactggcattgccccctt ccggggattctggcaggagcggctgcatgacattgagagcaaaggtgaggctggtgactaaaggactgcctgaagggagt cacacaatctagggacagaggggtggggctggaaggcaggaaataggaaagagagggcaggaaacaaagtccacaaagct gaaaagacgctcatgagaccaaggggagggcaggtaccaaaggcaagggctgggccctgagcttctggcttcctggtgcc tggtacatagtaggtgttgactggattgaggacaaaggaaaatagaattttcaaagggattagggctaagactcaaagaa gaactgcccaaggtggattcttgactgtgccagagctgaccgaggtctgtccaagacctaaggatgctacaaggtgttca tattgagcatggggtgcccagggtggtctgtcaatcaaaagaagagggctgtgactgggaggagagttataagtatggga gaatatgaagtgggagcggggaaggggactgcgatgtcacacaatgcaaagggcatggaattctgagtccgaagccgcgc attctagcgcactccaccaggggccaccacctcacccgcgcttcccttccctctgtaaatcagggctgtgcagggtctct gtgaaagcattctacactctcttagagatgaaacagccaaagtaatggtggtttcagcccaaaacgctgggctgccaggc tgggcgacggtggcctgtggggaggccccactagcactgtgccccggagaagagccttcccaagcgcggggttgcttgca gggctgcagcccactcccatgactttggtgttcggctgccgatgctcccaacttgaccatctctaccgcgacgaggtgca gaacgcccagcagcgcggggtgtttggccgagtcctcaccgccttctcccgggaacctgacaaccccaaggtgtgagacc ctgagggcgcaatggtaacctgaagatagggagagaggggaggactcgcgctctccagcggggcacaccaaccacggccc tcccgtggcctcccacgaccactcagccacccctgcacactctggcccacccttgtgccccggcccctctaggccccgcc tcctcccgcccctgccccgcccctttggctctgccctgttgacaacgccccagggcacgcaggccccaccaggcccgctc cggagaatttcaaggtccagggccagccagcagccccgggctgcccccgcgcccacccccaccagggcccgccctaaccc cgccgccccgcagacctacgtgcaggacatcctgaggacggagctggctgcggaggtgcaccgcgtgctgtgcctcgagc ggggccacatgtttgtctgcggcgatgttaccatggcaaccaacgtcctgcagaccgtgcagcgcatcctggcgacggag ggcgacatggagctggacgaggccggcgacgtcatcggcgtgctgcgggtgcggaggggcgggccgggcctgagcgtgcg gggttcctgctaaggtctccgagtcgggttctgatccactgtgctcttttccgacaggatcagcaacgctaccacgaaga cattttcgggctcacgctgcgcacccaggaggtgacaagccgcatacgcacccagagcttttccttgcaggagcgtcagt tgcggggcgcagtgccctgggcgttcgaccctcccggctcagacaccaacagcccctgagagccgcctggctttcccttc cagttccgggagagcggctgcccgactcaggtccgcccgaccaggatcagccccgctcctcccctcttgaggtggtgcct tctcacatctgtccagaggctgcaaggattcagcattattcctccaggaaggagcaaaacgcctcttttccctctctagg cctgttgcctcgggcctgggtccgccttaatctggaaggcccctcccagcagcggtaccccagggcctactgccacccgc ttcctgtttcttagtcgaatgttagattcctcttgcctctctcaggagtatcttacctgtaaagtctaatctctaaatca agtatttattattgaagatttaccataagggactgtgccagatgttaggagaactactaaagtgcctaccccagctcatg tggattacagttttttttttttgtttttttttttttgaaacggagtctccctctgccgcccgggctggagtgcagtggcg tgatctcagctcactgcaacctccaccccacaagttcaagtgattctcctgcctcagcctcccaagtagttgggattaca ggtgcctgccaccgcgcccggctaggttttgtatttttagtaaagacggggtttcaccatcttggccaggctggtcttga actcctgacctcgtgatccaaccgcctcagcctcccaaagtgctgggattacaggtgtgagctactgcacccggcgtgga ttacaattataaaatgacaagatttctgttttaacctgtgcagttgtgggtatgtggtggggaaaggggtcattctttta acagagtcctacacgccacttgaccctgcactctgaaaacatggtttccagccagtctgggctgctcccccgtgcagttc tcaggctcgtaatcgagaaggcaggtgcagcactcagctgccaggagtggggcctgccagaaacaagagtcacagagatg tgcaacagccatgagcaagctt (SEQ ID NO: 12216) cagagtggacgcacagtaacatgggcaacttgaagagcgtggcccaggagcctgggccaccctgcggcctggggctgggg ctgggccttgggctgtgcggcaagcagggcccagccaccccggcccctgagcccagccgggccccagcatccctactccc accagcgccagaacacagccccccgagctccccgctaacccagcccccagaggggcccaagttccctcgtgtgaagaact gggaggtggggagcatcacctatgacaccctcagcgcccaggcgcagcaggatgggccctgcaccccaagacgctgcctg ggctccctggtatttccacggaaactacagggccggccctcccccggccccccggcccctgagcagctgctgagtcaggc ccgggacttca caaccagtactacagctccattaagaggagcggctcccaggcccacgaacagcggcttcaagaggtgg aagccgaggtggcagccacaggcacctaccagcttagggagagcgagctggtgttcggggctaagcaggcctggcgcaac gctccccgctgcgtgggccggatccagtgggggaagctgcaggtgttcgatgcccgggactgcaggtctgcacaggaaat gt cacctacatctgcaaccacatcaagtatgccaccaaccggggcaaccttcgctcggccatcacagtgttcccgcagc gctgccctggccgaggagacttccgaatctggaacagccagctggtgcgctacgcgggctaccggcagcaggacggctct gtgcggggggacccagccaacgtggagatcaccgagctctgcattcagcacggctggaccccaggaaacggtcgcttcga cgtgctgcccctgctgctgcaggccccagatgagcccccagaactcttccttctgccccccgagctggtccttgaggtgc ccctggagcaccccacgctggagtggtttgcagccctgggcctgcgctggtacgccctcccggcagtgtccaacatgctg ctggaaattgggggcctggagttccccgcagcccccttcagtggctggtacatgagcactgagatcggcacgaggaacct gtgtgaccctcaccgctacaacatcctggaggatgtggctgtctgcatggacctggatacccggaccacctcgtccctgt ggaaagacaaggcagcagtggaaatcaacgtggccgtgctgcacagttaccagctagccaaagtcaccatcgtggaccac cacgccgccacggcctctttcatgaagcacctggagaatgagcagaaggccagggggggctgccctgcagactgggcctg gatcgtgccccccatctcgggcagcctcactcctgttttccatcaggagatggtcaactatttcctgtccccggccttcc gctaccagccagacccctggaaggggagtgccgccaagggcaccggcatcaccaggaagaagacctttaaagaagtggcc aacgccgtgaagatctccgcctcgctcatgggcacggtgatggcgaagcgagtgaaggcgacaatcctgtatggctccga gaccggccgggcccagagctacgcacagcagctggggagactcttccggaaggcttttgatccccgggtcctgtgtatgg atgagtatgacgtggtgtccctcgaacacgagacgctggtgctggtggtaaccagcacatttgggaatggggatcccccg gagaatggagagagctttgcagctgccctgatggagatgtccggcccctacaacagctcccctcggccggaacagcacaa gagttataagatccgcttcaacagcatctcctgctcagacccactggtgtcctcttggcggcggaagaggaaggagtcca gtaacacagacagtgcaggggccctgggcaccctcaggttctgtgtgttcgggctcggctcccgggcatacccccacttc tgcgcctttgctcgtgccgtggacacacggctggaggaactgggcggggagcggctgctgcagctgggccagggcgacga gctgtgcggccaggaggaggccttccgaggctgggcccaggctgccttccaggccgcctgtgagaccttctgtgtgggag aggatgccaaggccgccgcccgagacatcttcagccccaaacggagctggaagcgccagaggtaccggctgagcgcccag gccgagggcctgcagttgctgccaggtctgatccacgtgcacaggcggaagatgttccaggctacaatccgctcagtgga aaacctgcaaagcagcaagtccacgagggccaccatcctggtgcgcctggacaccggaggccaggaggggctgcagtacc agccgggggaccacataggtgtctgcccgcccaaccggcccggccttgtggaggcgctgctgagccgcgtggaggacccg ccggcgcccactgagcccgtggcagtagagcagctggagaagggcagccctggtggccctccccccggctgggtgcggga cccccggctgcccccgtgcacgctgcgccaggctctcaccttcttcctggacatcacctccccacccagccctcagctct tgcggctgctcagcaccttggcagaagagcccagggaacagcaggagctggaggccctcagccaggatccccgacgctac gaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcagttcccgtcggtggcgctgcctgccccact gctcctcacccagctgcctctgctccagccccggtactactcagtcagctcggcacccagcacccacccaggagagatcc acctcactgtagctgtgctggcatacaggactcaggatgggctgggccccctgcactatggagtctgctccacgtggcta agccagctcaagcccggagaccctgtgccctgcttcatccggggggctccctccttccggctgccacccgatcccagctt gccctgcattctggtgggtccaggcactggcattgcccccttccggggattctggcaggagcggctgcatgacattgaga gcaaagggctgcagcccactcccatgactttggtgttcggctgccgatgctcccaacttgaccatctctaccgcgacgag gtgcagaacgcccagcagcgcggggtgtttggccgagtcctcaccgccttctcccgggaacctgacaaccccaagaccta cgtgcaggacatcctgaggacggagctggctgcggaggtgcaccgcgtgctgtgcctcgagcggggccacatgtttgtct gcggcgatgttaccatggcaaccaacgtcctgcagaccgtgcagcgcatcctggcgacggagggcgacatggagctggac gaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaagacattttcgggctcacgctgcgcaccca ggaggtgacaagccgcatacgcacccagagcttttccttgcaggagcgtcagttgcggggcgcagtgccctgggcgttcg accctcccggctcagacaccaacagcccctgagagccgcctggctttcccttccagttccgggagagcggctgcccgact caggtccgcc (SEQ ID NO: 12217) gggcccagagaaagagctgtccccggggccttggggacagggtgacagccacccagagatcatggagaaggggacgtaag gaagacctcacagaggagtcatcctgcgactgtgttggttgggtccttcaggaagcagagtcccaggagttggaagcata agaggaatactgcgggcaatgcctgagaaagataacagggaccgggagcaggagtgagttgggcaggggaaggatcaggc ccacaatgccaggctcacacctgcagaggagggaagaagaagaagggcctcacatcagcccagcgggggatgttacgccc acagacgccccggggctcagttactgtctaagtgttagaaataaattttcggtgccacaaaagaaatagcactcagatta aatgttcccagcaaggcaattttacttctatagaagggtgcatctcacagatggagcaatggcaagagcacacctgaaca agggaagggaaggggtttttatccctaaggcaggtagcccctacagctgtgttgttcccctattggctagggttggacca caccgtctgagctaattgttactggctattttaaagagagcaggggtaagagccggattggcagggtaagtagtttggca ggaaggacggtcacagaacaggtgactcaggatgactcaggtcagagcaggtgaccagtggtgactcagttcggagcagg tgatagaagctaggagggggttgtttactgaaactaggggcaaggagacgaagagaacatgaaagttaaactttaagatg aagaacaaagctgaacatactgatgcattggatctttggagaggatctcagaactcattgtacttaatttacaggctaaa accttagaagaggaatttattatatcctacacaagactccagggaagcacatggccttggactgaaggctggcatctgga agctgtcagccaccagcaccttctgcagcaggtacctgctctctaagagggaggcctgggtggtgcacctccagagctgc ccaggctgggcctcaaggaagaaaaagattttcatttgtcagaggcggaagggagaggtggagggaacagcacagcagcg gcccaggggcagggaagcacaggaccattagggagacacgagaaagcccatttgtctagaacagaggattcaagcagtgc accaaggaaaatgagggccaggccaatgtgctggagtggctttgttcttggctgagggttttgggtagtgccaaagcgta aggtaagccctgctttccagaagaatctagcagagtgtggagcccagatgggactggaaggcctgggaggggtcaggtgg ccacagggacgggccacagccagtggtgcaggcaagaagacaatggccatccatggtggctcacacctggaatcccagcc cattgggaggtcgaggcaggtggatcacctgaggtcaggagttcgagaccagcctggtcaacatggtgaaaccctgtctc taataaaattataaaaattagccgggcgtggtggtgggtacctgtaatctcagctactcaggaggctgggtcaggagaat cgcttgaacccaggaggcggaggttacagtgagctgagatagcaccattgcattccagcctggacaacaaaagcgagact ctgtctcaaaaaaaaaaaaaaattagccaggcgtggtggtgggtgcctgtcgtcctcgggaggctgaggcatgagaatca ctccgggaggcagaggttgcaatgaaccaagatcacaccactgcactccagcctgggtgacagagcaagactctgtctaa aaaaaaaaaaaagacagaaggatgtcagcatctgatgctgcctgtcaccttgaccctgaggatgccagtcacagctccat taactgggacctaggaaaatgagtcatccttggtcatgcacatttcaaatggtggcttaatatggaagccacacttggga tctgttgtctcctccagcatggtagaagatgcctgaaaagtaggggctggatcccatcccctgcctcactgggaaggcga ggtggtggggtggggtggggcctcaggcttggggtcatgggacaaagcccaggctgaatgccgcccttccatctccctcc tcctgagacaggggcagcagggcacactagtgtccaggagcagcttatgaggccccttcaccctccgatcctccaaaact ggcagaccccaccttcttcggtgtgaccccagagctctgagcacagcccgttccttccgcctgccggccccccacccagg cccaccccaaccttatcctccactgcttttcagaggagtctggccaacacaaatcctcttgtttgtttgtctgtctgtct gctgctcctagtctctgcctctcccagtctctcagcttccgtttctttcttaaactttctctcagtctctgaggtctcga aatcacgaggcttcgacccctgtggaccagatgcccagctagtggcctttctccagcccctcagatggcacagaactaca aaccccagcatgcactctggcctgaagtgcctggagagtgctggtgtaccccacctgcattctgggaactgtagtttccc tagtcccccatgctcccaccagggcatcaagctcttccctggccggctgaccctgcctcagccctagtctctctgctgac ctgcggccccgggaagcgtgcgtcactgaatgacagggtgggggtggaggcactggaaggcagcttcctgctcttttgtg tcccccacttgagtcatgggggtgtgggggttccaggaaattggggctgggaggggaagggataccctaatgtcagactc aaggacaaaaagtcactacatccttgctgggcctctatccccaagaacccaaaaggactcaagggtggggatccaggagt tcttgtatgtatggggggaggtgaaggagagaacctgcatgaccctagaggtccctgtggtcactgagagtgtgggctgc catcccctgctacagaaacggtgctcaccttctgcccaaccctccagggaaaggcacacaggggtgaggccgaaccttcc gtctggtgccacatcacagaaggacctttatgaccccctggtggctctaccctgccactccccaatgccccagcccccat gctgcagccccagggctctgctggacacctgggctcccacttatcagcctcagtcctcacagcggaacccaggcgtccgg ccccccacccttcaggccagcgggcgtggagctgaggctttagagcctcccagccgggcttgttcctgtcccattgtgta tgggataggggcggggcgagggccagcactggagagccccctcccactgccccctcctctcggtcccctccctcttccta aggaaaaggccagggctctgctggagcaggcagcagagtggacgcacagtaacatgggcaacttgaagagcgtggcccag gagcctgggccaccctgcggcctggggctggggctgggccttgggctgtgcggcaagcagggcccggatcccatgccctg cctcactgggaaggcgaggtggtggggtggggtggggcctcaggcttggggtcatgggacaaagcccaggctgaatgccg cccttccatctccctcctcctgagacaggggcagcagggcacactagtgtgcaggagcagcttatgaggccccttcaccc tccatcctccaaaactggcagaccccaccttcttggtgtgaccccagagctctgagcacagcccgttccttccgcctgcc ggccccccacccaggcccaccccaaccttatcctccactgcttttcagaggagtctggccaacacaaatcctcttgtttg tttgtctgtctgtctgctgctcctagtctctgcctctcccagtctctgagcttccgtttctttcttaaactttctctcag tctctgaggtctcgaaatcacgaggcttcgacccctgtggaccagatgcccagctagtggcctttctccagcccctcaga tgacacagaactacaaaccccagcatgcactctggcctgaagtgcctggagagtgctggtgtaccccacctgcattctgg gaactgtagtttccctagtcccccatgctcccaccagggcatcaagctcttccctggctggctgaccctgcctcagccct agtctctctgctgactgcggccccgggaagcgtgcgtcactgaatgacagggtgggggtggaggcactggaaggcagctt cctgctcttttgtgtcccccacttgagtcatgggggtgtgggggttccaggaaattggggctgggaggggaagggatacc ctaatgtcagactcaaggacaaaaagtcactacatccttgctgggcctctatccccaagaacccaaaaggactcaagggt ggggatccaggagttcttgtatgtatggggggaggtgaaggagagaacctgcatgaccctagaggtccctgtggtcactg agagtgtgggctgccatcccctgctacagaaacggtgctcaccttctgcccaaccctccagggaaaggcacacaggggtg agccgaaggcccttccgtctggtgccacatcacagaaggacctttatgaccccctggtggctctaccctgccactcccca atgccccagcccccatgctgcagccccagggctctgctggacacctgggctcccacttatcagcctcagtcctcacagcg gaacccaggcgtccggccccccacccttcaggccagcgggcgtggagctgaggctttagagcctcccagccgggcttgtt cctgtcccattgtgtatgggataggggcggggcgagggccagcactggagagccccctcccactgccccctcctctcggt cccctccctcttcctaaggaaaaggccagggctctgctggagcaggcagcagagtggacgcacagtaacatgggcaactt gaagagcgtggcccaggagcctgggccaccctgcggcctggggctggggctgggccttgggctgtgcggcaagcagggcc cagccaccccggcccctgagcccagccgggccccagcatccctactcccaccagcgccagaacacaggtaagggccaggc agctaggagcaggtgggcaacaagggtggtgtcaaggcctgaagcctggggctgggaaggtctggaacttgtagctgagt cgggagggccaggtcacaaatgcaaaagggctattaatgtgcatagaacaggacagtctgggaggctcagaaaggagacc aggatcagagtcggcaggtgaagctgggagtaagggtgccagctatagaatctggccagggtttgaatgctgctctgccg ccaggagctgtttgactttgagcaagttacttaatctctctgaacctccatttatataaaacgagatatggcaatactta ctccatggggaagtaagtttctagctcacagcaagccttcaacagcagcgatgattatttagctggagaagaaaggagct gacagcagtggttacaggagtgagaaagtggggtctcccagaagagggagagagttgggcaggaaactcgggcccttggg gtaagcaggctgagaagacagagccaccaggcttttttcccctgctccagccccctctcctcgtggctgtcacccgaaaa ctggaccatgcagttcccacaagagtcctcccgggggtagaggtcccaggagggaggaaagacccggaggcctggtgggg tgccaggccgggggcaggctggggctgcaggcagctatgcagggaaggctgagggccggggccctgctgctcaggcgcac ccttggcctgagtccctcccttcctccctgccgctggtggctctgggaggaagtgataaggcctgcgaggcttcccttca cacatggggctgctgtcaggaggggttgtgagtgcggagggaaatcagagctgaggaatccctgcagggcttccctccac tcaagcaccaggctctgtccccctcagggtagggcttatagcagctttgcggggggtggacaccccatctccagaagagg tgaggtgggcgctgcaggtgggatgcgaacttagcctcgggtcaggggctcaggagctcagcaccagcagcccctgcagc ccaggaccctggtctataaacggaggcacagctcgcctctagctcctaaggcatggggaacgccagaaggcatgcggcag gtgggctgtgagatcgccagtgctgtaacaggggcctccgggtgacatctgggaaggctgaaaggaaacaaacccttcct gatgaccctatccctggctcccaacagccccccgagctccccgctaacccagcccccagaggggcccaagttccctcgtg tgaagaactgggaggtggggagcatcacctatgacaccctcagcgcccaggcgcagcaggtaaggccggcatgccctgtc cccatcgtctccagggaaagggtgggtaaggcctggcctcagatggggccggagagggaagctcaacccttctttgaatt ggtcccttgtttccaaaaagaggagaggactgggaagaaccagaggagttgagggacatgcacgggacttgggtgaccct cagcctccagccttacccccaaccctggctcaaacttttcccccatcccacccctgcaccccttttccccctcccacccc tgcacccttcctccctctcccccaccccacccctgccccccctcccatcccagctctaaacccctcctccctctcccccg tcccacccctaaaccccacctccctgtccccctctaaacccctcctccctgtccccctctaaaccccacctccctctccc catcccacccctgcacccttcctccctctgcccccgtcccacgcctgtactcctcctccctctcccccgtcacacccctg cacccctcctccctctccccatcccatccctgcacccctcctccctctgcccccgtcccacccctaaacccctcctccct ctgccccaccccacccttgcacccctcctccctcttcccccgtcccctgcctgcattcctcctccctctccccatctcac ccctgcacccctcttccctctcccacccctgcacccctcctccctctccccgtcccaccctgcactcccgccctctccag cgtcccacccctacacccctcctccctctgccccattccacccctgcaccccctcctccctctgccccgacccacccctg cacccctcctccctctcccccgtcccacccctgcatccctcctccctctgccccgtcccacccctacacccctcctccct ctcccccatcccacccctaaacccctcctccctctcccctgtcccatccctgcacccttcctccctctccccgtcccatc cctgcacccttcctccctctccccgtcccatccctgcacccctcctccctctgctcccatcccacccctgcacccctcct ccctctgcccctaccccacctctgcacccctcctccttctccccatcccacccctgcacccctcctccctctgcccctac cccacccctgcacccctcctccttctccccatcccacctctgcacccctcctccctctcccctctcccacccctgtaccc ttcctccttctccccgtcccacccctgcacttctcctccctctaacccatcccacccctgcacccttcttccctctcccc catcccaccactgcacccctcctccctctccccctgttccacccctgcacccctcctccctgcccccaactcccatccca cccctgcaccctggcctgtcctgacctttgcactccctcgacccaggatgggccctgcaccccaagacgctgcctgggct ccctggtatttccacggaaactacagggccggccctcccccggccccccggcccctgagcagctgctgagtcaggcccgg gacttcatcaaccagtactacagctccattaagaggtgacagcttcccggacgccacagcctcccttgtcccactgaggc cccagaaaccccgtgacgaccttcccatgaccccctcccttcccagatcctaacaccacgtgggcccctcccgccctccc ccagcacttgcacaaagcctggaggagggcctccctgtcccacacaacttcctgcttgtccccttcccacccctctcctc cccaggagcggctcccaggcccacgaacagcggcttcaagaggtggaagccgaggtggcagccacaggcacctaccagct tagggagagcgagctggtgttcggggctaagcaggcctggcgcaacgctccccgctgcgtgggccggatccagtggggga agctgcaggtgcggctggccagcgactgagagacccgggcgctaccaaaaggggagcggggtggcggggcagttcctaag gcttcccgggggctgggaggtcccaaactgtgggggagatccttgccttttcccttagagactggaaaggtagggggact gccccaccctcagcacccaggggaacctcagcccagtagtgaagacctggttatcaggccctatggtagtgccttggctg gaggaggggaaagaagtctagacctgctgcaggggtgaggaagtctagacctgctgcaggggtgaggaagtctagacctg ctgcaggggtgaggaagtctagacctgctgcgggggtgaggaagtctagacctgctgcgggggtgaggacagctgagcgg agttccctgggcggtgctgtcagtagcaggagcagcctcctggaaaagccctggctgctgcttctcccccaagagagaag gcttctcccgccaggccagtccagtgcagcccctcacccacacccactgctaccccagttcccctgcttcggcccgcacc ctccctcacaccccagcccacagactcggggctggccttagttactggaacgcctgtgaccacagcactaagagaagcaa gctgccccatgggggacttggtccccatggccttggcctccttcaccatcactggccgccaaagagtttgaaataaagcc acgtgcccagtgaatcccaaaggaacctcaactaaaataaaaacaatcctatctgacacttgcctgaccctctaagtcat tcaaagctttagctcaacttcgatccatctgagctgccatagtggaccccactcagagctgcgtccctcccttgacccca ggttggtccctgccactcccctgcccctgtcactgacacatgtttcctcctccctcaggcaggagtgggacctcccagcc tcctcctggggcctccactcagaatgtcaggatgagcagggtcctaggaggcctctggtgcagccttcccttcccaccat ccatgtgctcaaagagaatcacccgtcctttcttgaatgccatggatcatgggggatttgctgcccacactcctaggcgg cctcttagacatccgttggtgcctaacccaagcatcagtttggcagaggccgagtccctcctctgtactggataccaagt cagcttccatagggatggggagacacctggcccagggaggagatgagaagcagcccggatggtgctacatatgtcagaga gcagggcaggaagggatcagtgtggctgccaatggtcaggagggcgccatggagtgaaccatggcccctgcctcctcaac caagaagtcctctggagctgatactcaagaccccccgtctctctcctcaccctcctctcccgctgcctcggctggctcag gtgttcgatgcccgggactgcaggtctgcacaggaaatgttcacctacatctgcaaccacatcaagtatgccaccaaccg gggcaaccttcggtgagtgccccccaccatgccaggccccagccttcttccccaaggcagggaaggcggggctctgacca gctctttccccatgcgtgccagctcggccatcacagtgttcccgcagcgctgccctggccgaggagacttccgaatctgg aacagccagctggtgcgctacgcgggctaccggcagcaggacggctctgtgcggggggacccagccaacgtggagatcac cgaggtgggcaccgagggccacccatgagggtgtccccaaggtggagaatgaggaaaccagtgggagaaggctcggggga tccaggcaggaagaggggagcctcggtgagataaaggatgaaaaacaccaaaggaggggtgcctgggtggtcacggagac ccagccaatgagggaccctggagatgaaggcaggagacagtggatggaggggtccctgaggagggcatgaggctcagccc cagaaccccctctggcccactccccacagctctgcattcagcacggctggaccccaggaaacggtcgcttcgacgtgctg cccctgctgctgcaggccccagatgagcccccagaactcttccttctgccccccgagctggtccttgaggtgcccctgga gcaccccacgtgagcaccaaagggattgactgggtgggatggagggggccatccctgagcctctcaagaagggcctgcaa gggggtgctgatcccacaccccaacacccccaggctggagtggtttgcagccctgggcctgcgctggtacgccctcccgg cagtgtccaacatgctgctggaaattgggggcctggagttccccgcagcccccttcagtggctggtacatgagcactgag atcggcacgaggaacctgtgtgaccctcaccgctacaacatcctggaggtgaggtgcgggatggggctcgggcaccgaat gcacctgtccaaggcaggagtctggctctcactccatccccaaaatgccagccacggggacaatcagagcaggtccaggg ttgcctcctaaatgggaactgaggacaagctctagaaccactgaagcaaaggggtagggggtggcaggggtgtgtgtggg ggtgtgagtgggtgagtgtgagagtgtgggtttctggggtgtgcagtgggtgagagtgtgggcttgtggggtgtgtagtg ggtgtgagactgtgggtttgtaggggtgggtgagtgtgggtgtgtgggggtaggtgggtgtgggtttgtgggtgtgtata ggcagtgactgtgagactgtgggtttgtgggggtaggtgactgtgggtttgtggggtgtgtaggggtgagtgtgtgtggg tttgtaggggtaggcgagtgtgggtttgtggggtgtgtaggggtgagtgtgtgtgagtttgtaggggtaggcgagtgtgg gtttgtggggtgtgtaggggtgagtgtgtgtgagtttgtaggggtaggtgagtgtgggtttgtggggtgtgtagggggtg tgtgtgggcttgtaggggtaggcgagtgtgggtttgtggggtgtgtaggggcgagtgtgagagtgtaggtatgtgggtgt gagtgtggatgtgtgtaggcggtgagtgtgaaattgtgggtttgtgggggtgggtgggtgtgagtgtgtgggtttgtggg tgggtgtgggtgtgagtgggtgggtgaggggggcatggggatgggtgtgaacatgtagttgttctttcaggcataggacc catagctctagagctttcat agattctcaaaggggaccttgactcggaaaaggttaagacccattttagagatgagaaa' ttaaagcctggagctgaggagcgactggcccaaagtccctctctgctctgaggtgcttcgcaggcaaaaacctgaaccag ccccctaggcagccaggcctcccaatggacaccactcacctcactccttccagccatgtacgggaaacagagatagtctc cccaccccacccccgtgatcacctctgtccctaccgatgccacacacccttctgccccaggatgtggctgtctgcatgga cctggatacccggaccacctcgtccctgtggaaagacaaggcagcagtggaaatcaacgtggccgtgctgcacagttacc aggtgcagaggcccagactggccaggaaggcaaagggtttgcatacgggggcagcaggggcgggggatggaggagaggca gccatttagaaactagggcaggatttggacaggcagaagaagttccgtagtcccagtgccatggcgcacactggctgcgg ttcggggacagggcaggtactattccaggcgctgtcatctggtggcttactgtgtgccagggaccttgctgtttactgca tgcccagtcatgctgattctcagggcatattgggtattgcagtttgtgggacccgctggatcctggaaacaaataccagg atcaagggcacaccaggagtcgtagtttgaggaagccggggcctgctgagaatttctgtgggctatttggtttggggacc aggcatgcagatgctggagattagagctgcttgttgcatgttgaacctgcagcatgaccatgcatgatgtggtttggggt gagggtgacattgtggtttgaggggacacagggtgtgttagatatggggtaatcgagggcacatgtggtttggggtgacc ggagtggtggaggaagaatgggcgaggtctgtgggtctggtttgagcctctccccctctctctcccttccagctagccaa agtcaccatcgtggaccaccacgccgσcacggcctctttcatgaagcacctggagaatgagcagaaggccagggggggct gccctgcagactgggcctggatcgtgccccccatctcgggcagcctcactcctgttttccatcaggagatggtcaactat ttcctgtccccggccttccgctaccaggtgcccaccctaatggctctgccagcctgggcccagctctaattctaagcagc ccctggggacctctaacctttccttttctttacctcccctcccaaccccatcatctctctgcagccagacccctggaagg ggagtgccgccaagggcaccggcatcaccaggaagaagacctttaaagaagtggccaagtgggtcccctgggagccccgc tctcccacacacaccctgggggccccactctcccccacacaccctgggggaccctgccccagcagtgttctggacctacc actcagtatcccaaaaccctgttgtgagggggttggacccttgcctggggaggccctgcctctgtgcacccgggacaccc tcacaccttcctctcccgcagcgccgtgaagatctccgcctcgctcatgggcacggtgatggcgaagcgagtgaaggcga caatcctgtatggctccgagaccggccgggcccagagctacgcacagcagctggggagactcttccggaaggcttttgat ccccgggtagggctgagcccaggggagcagggagctagaaagagggggctc atcagcatcttcaggggtgccctggagg acaggaagtgttacaagtcaggactcatgaggaacccggaaccacaggtgttcagagatcaagttggggcctgaatcttg cactgccagggaggccagagtgaggagggcagggcctccgggggccacagcacccaggacatctgtcttcccacccacag gtcctgtgtatggatgagtatgacgtggtgtccctcgaacacgagacgctggtgctggtggtaaccagcacatttgggaa tggggatcccccggagaatggagaggtgagaacttccaggaaaggggctgctgggaatgaggagagactcagaattggag tgactgggcaggaacctctgcccaacacacacacacacacacacacacacacacacacacacacacacacacacacacac acacacacacacacacgccaggatggaaagggagatgctaagagacccctggagcctgaaaccccacacaacgtacgctc ccagcccacccatgtggctgcctccctgcaagcacatttgcttaactgcgcgtccccaagtcatttccattatcagtgca agtttttaatacaaggaaggcacatcctggctgaccaagaggttagactgtgctcgggcactgacaagaaaaacagggat acgtcactgagggcggcttctaggatgcgggtaatgtttcttaatgggatactggttacacaggtgtgttcagtttgtaa aaatccacagagctgtacatttacaacatgtacaacactattccagcattttattttatttgttttatttattttgataa cctatttacgttgcccaggctggccttgaactcctagcctcaagagatcctcctgccgcaggctcctttttcaaaagaag aaattgagcgctgtttagatgccaacatagattaaataacttcactttttaaaaagaaacacaaagctagagtaccatca ttgaattccttctcttgcaagcttaggtatctctgaggtgccccaggctaggctcatttctgagtcttacctgctccagc ttctaggtgttaaaggccttattagcactaagtacttcctcagtactcttttttcttttttcctttgagacagggtctca ctttgtggcccaggctggagtgcagtagtacaatcacggctcactgcagcctcaacctcctagactcaagcaatcctccc acttcaacctcccaagtagttgggactacaggcgcatgccatgatgcctagctaatttttgtattttttatagagatggg gtt cgccatgttgcccaggctggtctctaactcctgggttcaagcaatccacctgcctcggcctcccaaagtgctgcga ttatagacgtgagccactgcacctggcccgcagtatcttaagcaagttggaatctcgtgaaaccctttttgctgccttag tgtccgtttcagccctcattcttacctaccttttcaagaaaaatagcaccagcaattgacttttttttagcataaaggtg tatagaacccatataacctacagccttcacaaggcatagcacattttcaccaccctggaaagttccctcatcagttcctc acgtgaatcccttcccagtctgtctccctgccagaagtgtctgtcaccacagaatagtttcgcctgctctagaacggcac ctagatggaagcacgcagtgttgcggcgtctcctgctgaggctgtttttgaggcgcactcgtgttgctgcgtgactcagt atttcactcattctgctgctgagtgccgttcattgtgtgaatatccccagtttgtttacccattctcttgttggtgacac ttgggctgtttccaggtcggggctattatgaataaacctgttatgaacattctgtacccggcttttgtgggcttatgttt ttatttctcttgggtaaaacctaggagtagaattggtaggtca agggtagatgcatgtttaatctttcacttttttaaa aaataaaactgccaggccaggcgcggctgctcacgcctgtgatcccagcactttgggaggcccaggtgggtggatcactt gaggtcagaagctcaagaccagcctggccaacatggcaaaaccctgtctctactaaaaatacaaaaattagctgggcatg gtggcgcacgcctatagtcctagctactcaggaggctaggcgggagaattgcttgaacctgggaggtggaggttgcagtg agccgagatcacgccactgcactccagcctgggtgacagagcaagaattctacttaaaataaaatacaaataaataaaat aaaactgtcaaacagcaaagcaaattaaactgccctttaacatctgtgcagttcaatgtatgttaattttatcccaaatt tttaacaaatctaggaatacagctcacagaaaatggggtatattcactaaaaataaggaatatttatagcaaatttgttt gtaataccccacactggaaacaattcaaatgaccatcgacaaatactgataaattgtgg atattcaagtgccatatcgc actaagtgtgaacgaaacacaaccacacacaacagtgcaggtgaatctgaaaaaatgtgaagagaagaaaaagccagacc aaagaatacatactgtactacagggttcactttatataaagttcagaaacaggcagaactaatccacggagttagaaatt aggagaggagttagtcactgggatgggggtggcagtgacaggaagaaggcacgaagttggcttctaggatgcgggtaatg tttgtttgtttgtttgtttgtttgtttttgtttttgagctggagtctcactctgttgcccaggctggagtgcaatggcgt gatctcggctcactgcaacctccgcctccccggttcaagcgattctcctgcctcagcctcccgagtagctgggattacag gtgcccgccaccatggccagctaatttttgtgtttttagtagagacgcgtttcaccatgttggccaggctggtcttgaat ccctgacctcagcctcccaaagtgctgggattacaggcgtgagccaccacgcccagccacgggtaatgtttctcgatggg atgctggttgcacaggtgtgttcagtttgtgaaaacttacagagttgtacatttacaacatgtgtgcacctctggacttg tgttgcacgttgacaaaacattcaaaaatgaaattcaaatcgttcttgctaactctggcgcacttgggaaccagcaccca gaggcatctgcagttgagcaccagatgcagttccttccagcttccttccccctgggaggtccgcttgatgccacttcttc atggcagcacaaacaaggccatggtcttctgaggagggcaacctgcacaatgtctgctagtgaccaggacactgctgaag gaactgagagtttgtccacccatgaaatccactaaaacaggaaagattttgctctagccgttgttagccaggagtgagga aagagctgtgccctcccctgcagctgcgaggacgatctgcctgccccaacaagtggggattcagcaactccacttctaag gattacccagctgaagcatttaaaagtgggagcaaggcacacgtacaagggcgtttgagagagcacctgttcccagacca ccgagctgcccttcagtctcagtgaagtacaatgtagccactaaaaagactgaggtcatgttttggaaagtccaggccgg aggatcgcttgagcccaggagttcaaggccagactgaacaacacagcgagactccatctcttcagaaaatttaaaaatta accaagagtggtggcacgcacctatagatctagctactaggaaggcagaaaaatcccttaagcccaggagtttgaggtta cagtgaatgatgatggagccactgcaccccaacctgggcgacagagcaagacccatatctaaaaacaatactactactta cgtcaatattgttgtattgacctggagggatgtctgcaataaattattgattaaaaccaaggaagtacagtatggtacca cttttacttaaaaaaaaactataaatatgcacgtgcacgtaagttcaaggaaaaagggctggaaggttaacacctgtgaa tggcgcatatgcccggaggaagatggggtggtctttgtcttatcactttacacatttctgtaatgtcatttttcaaaaac atcagatcgcttttgaaattttcaaaacaaataaaaattaagtgacaaatcaataataatgaggatcagctggtacagtt ttaaacttctatgtagtttgaaatgaaacaaaactaaccctgatgcaaacactcccctcgccagagctttgcagctgccc tgatggagatgtccggcccctacaacagctcccctcggccggaacagcacaagtgagttgggtgagagtttgggggagct gggggagctgatgcatttggagacacaaacagaaagggggtctgaaaagctctccctctgtgcctcaagtcgttttccca ccaaaagccagggctccaggatgccctccattccaggctgcaatggcagtccagacctgcctgcttctgagagccgggac agtcctgaggtcttcagagatgggggtgtggtgtgtcagggccccaggctcggaaccccagggatgctggccctcagccc ctcccaagggcagggcctttcctgtccagaggcagagaccctgaagccgtccctggggctgggtctgggcctagcctgta tccccagggccctgtgacaaccttgtctttgtcctctcttgccaggagttataagatccgcttcaacagcatctcctgct cagacccactggtgtcctcttggcggcggaagaggaaggagtccagtaacacagacagtgcaggggccctgggcaccctc aggtcagggcctcaccaagaggggtgcaacgggtgggcaagctgcctgggcaaacgtggcctgcaaagggagctccactg acgacccctgcaccccaggttctgtgtgttcgggctcggctcccgggcatacccccacttctgcgcctttgctcgtgcgg tggacacacggctggaggaactgggcggggagcggctgctgcagctgggccagggcgacgagctgtgcggccaggaggag gccttccgaggctgggcccaggctgccttccaggtgagcccagcccagcccctgctctgactcctgccccctgggatgcc tcctcctgcctcactctgccctgattctgtttggttctttggtcccttcctgttccttccaaaatccaccctcatctctc catggcatagccagctcttctgggtcaggggcagaggatgacatggccctgccgaccacaggggtgcctagcccaggcag aagtgcagccgaaagagagcaggcagggccctggcaggagggagcttcagccaggcacaggctgggcctcacaagtgggc gcacaaagggagggggtgcagggcagggcaggggaccccacccaggatgggcaggatggagggagaaggaagggacagag agaaggtcagacagaggcaagggctgaagctgaggccagcacagaagccacaggaagccagaggccagacagcctggggc ggtgcctgcaccagaactggtccgggccaggcaagcaagcacagggagaggtggatccctgggggctgtggctttttaag cctgggcttcctcaggggcagtgctgcctgtctggggatcatgtctgcagttgacaagggctcggtctccσcagtgccac actgttcagggcagtgctgctgtcccggggcccaggctggagctcagcagatttgccttgattggaggaggagggcatcc taggaggagagggagtgggggctacctcagggacggggaggtcaggctgcagaaacaσataggccctgattgggaagaag ggacacggtaaaataagctctaaaagaatttaaaacaaaaagagccattgcagcgggatgagaccacatcatcaggtttt gggaataggactttagaggcgtaggatccattacagcatcaccgaaccagaagcaggaaggctgagctaagcagagcagc agcagtggagataggaaggaagggagggaggggccgaggaaggaaggaagagatataagacttcacacgcaccacaaaag aaagattaacgggacttggtgatatgaggctcagccaatcacgggtgagccctgcatttcaagcctgggactggcccagc agttttccagctgtgtgcctgaccaggagtagacgggatccacaccctcccagggatctgccccgtggggtcccctctgc cgcccgaattgtgcgtcccttcccaggagcacttactatctgcacgcactttgtggaaagctaagggctttacataaagt atctcatttaatcttcaccagaacacaatgaggtgtaaagatggggaaactgaggcatgtcactgtaagtacgggattcg gaatttgaatgcaggtctgaacacacagacgccttcacagagctaccgtgtgccaagcactatgcttctcggatcacggg attaacacgcaccagataaggaacgatgcaccaatcaggacgtgcagagaaagagccagccgggtccctgggcccagcgg ccaatccatgaaatgggctggcggaaaaggtgctgtccttggcgccggcctcagccactggggctgccaaccccccagga gcaagacgcagtgaagccgcccaggcgcctcactagggcgacccctggtggcgggaggtcctcagccctcaccggcctgt cccgcaggccgcctgtgagaccttctgtgtgggagaggatgccaaggccgccgcccgagacatcttcagccccaaacgga gctggaagcgccagaggtaccggctgagcgcccaggccgagggcctgcagttgctgccaggtgggccctgcctcacccta acccggctggttctctgaggcccccacaccccgggactaaagcactctggggccaggccctgctccctagctcaggctgc ctcatttgcccctccccgcccccaggtctgatccacgtgcacaggcggaagatgttccaggctacaatccgctcagtgga aaacctgcaaagcagcaagtccacgtgaggacgacggctttaccgccccccaacccctgtcctgaacaccctgaccctgg accctcctcctcccacattctcccgcccccacccctctctgactccccataagtgcccctctccccacccccaggagggc caccatcctggtgcgcctggacaccggaggccaggaggggctgcagtaccagccgggggaccacataggtgtctgcccgc ccaaccggcccggccttgtggaggcgctgctgagccgcgtggaggacccgccggcgcccactgagcccgtggcagtagag cagctggagaagggcagccctggtgaggggcagcctgggaagcaacagggcacaccagccccatgcccagccccaccccc ^• ggccccaggcctccaggagctcaggacccgacccagggggtggccacctcctccacagctcagcaggcaggctcagagct ggctgtgctgcccactgccgggctggccttgttgctggaccatccccacaccctcaaatgcacccccaccaaaaggctgt cccctccctctgggctcctctccaaggctcccctagcaatctagcttgctctggagctggcactggggctatttgctgcc acatcaatgcctgggctttatttaaaataagggggtggagtcagaggcagaggagcccagaccaacccagtccggccagg ggcccccgaacaatacactgaggctacctagacaggccgaccccgctgctcaagggcaggctctctaacagtcaccaaaa cacaaacatcagcccaggtactgcagtcctgctgggccctgtcctcagagctccctgtgcactatccccaggtggccctc cccccggctgggtgcgggacccccggctgcccccgtgcacgctgcgccaggctctcaccttcttcctggacatcacctcc ccacccagccctcagctcttgcggctgctcagcaccttggcagaagagcccagggaacagcaggagctggaggccctcag ccaggttgggggccaccccaatgaggcacaggggctagagagacgggatgagctggggggaccccagtggcaggaaaccc ccatgcaaagtcccccctggactttcttctcctggctgacatgcactggtgctttaagacccagctcctcagggaggaat tcatggctggattctccaggtcttagagaaaactctattggcctgaactgagcagggagaaaccctaaagaggctcagtg ggggaggggtcaagaagggaggttactaggaagggctatggggcctccaacccactgcatcctgccccgccaggatcccc gacgctacgaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcagttcccgtcggtggcgctgcct gccccactgctcctcacccagctgcctctgctccagccccggtactactcagtcagctcggcacccagcacccacccagg agagatccacctcactgtagctgtgctggcatacaggactcagggtgaggcaacaagcaggagcaggcctggccacagca gggttgggaccggcccctctctggcccctcaccggcctctccttcccacccccagatgggctgggccccctgcactatgg agtctgctccacgtggctaagccagctcaagcccggagaccctgtgccctgcttcatccgggggtaagtgagatggagga cttggtggggagctgcccagggtcagggtggcagctttggtgaggagtgtcactggtgaggggtgtcactggaaacagga aggagctctgtaacatgtcaagggtgtggtgtcattaggtcacttcagaactctggctaagctttggctctctcattcat ttagactcagagttctgccctgaaactatagctcccagagccagagctggtatcaaaccggctggccctgtggctttctg aaagcttctgtgttcctctctatgtccctgggctgtctgatgttgggcagcatggcacctgggaactacagtcactaaat cctcactcaatccagggagaactactagttagggttaagaccaccctttggccttggtgtcaccaaggactcaaagaagg tgaaggttttggtttttttttcccccagagatggagtcttgctctgtcgcccaggctggagtgcagtggtacgatctcgg cttactgcaacctccgcctcccgggttcaagagattctcctatggcgtgaacctgggaggtggagcttgcagtgagccaa gattgtcccactgcactccagcctgggcgacagagccagactctgtctcaaaaaaaaaaaaaaaatattctcctgtctca gcctcctgagtagctgggattacaggcacccaccaccacgcccagctaatttttgtatttttagtagagacggtgtttca ctatgttggccaggctggtctcgagctcctgacctcacaatcctcccacctccgcctcccaaagtcttgggattacaggt gtgagccaccgcgcccggaccgagggtgaaggattttaagagacccttccttcatgctgtgtccagaagtcttgcccgct ctcgcagccaggaaccaaaagtcctggtaggactgagaacagttcctaggctgccatcagctgggcctggtgattcaaat ccacccaggtggctaaactacaaataaaccgtacccatctactgaacataaactaaataccactattaaggatacttaaa ataaacacacttagtgaacccattatgaactgaaagtgtctttcacccttcccacgttttctaaatcccctgagtcatct aagtattcttcaatccaaaatgaactatatttcctttggtgcaatctccagaaaccacagatccaaggagtttcagcaag tagagttgttttttgttttttgttttttttttaatttttttttgagatgggaagaacttgggtcctccttgctccaccca ccctgcatggtgagaatggtggagcaggaaaggcaaaggggacctgatggagtgtctctcctgccagggctccctccttc cggctgccacccgatcccagcttgccctgcatcctggtgggtccaggcactggcattgcccccttccggggattctggca ggagcggctgcatgacattgagagcaaaggtgaggctggtgactaaaggactgcctgaagggagtcacacaatctaggga cagaggggtggggctggaaggcaggaaataggaaagagagggcaggaaacaaagtccacaaagctgaaaagacgctcatg agaccaaggggagggcaggtaccaaaggcaagggctgggccctgagcttctggcttcctggtgcctggtacatagtaggt gttgactggattgaggacaaaggaaaatagaattttcaaagggattagggctaagactcaaagaagaactgcccaaggtg gattcttgactgtgccagagctgaccgaggtctgtccaagacctaaggatgctacaaggtgttcatattgagcatggggt gcccagggtggtctgtcaatcaaaagaagagggctgtgactgggaggagagttataagtatgggagaatatgaagtggga gcggggaaggggactgcgatgtcacacaatgcaaagggcatggaattctgagtccgaagccgcgcattctagcgcactcc accaggggccaccacctcacccgcgcttcccttccctctgtaaatcagggctgtgcagggtctctgtgaaagcattctac actctcttagagatgaaacagccaaagtaatggtggtttcagcccaaaacgctgggctgccaggctgggcgacggtggcc tgtggggaggccccactagcactgtgccccggagaagagccttcccaagcgcggggttgcttgcagggctgcagcccact cccatgactttggtgttcggctgccgatgctcccaacttgaccatctctaccgcgacgaggtgcagaacgcccagcagcg cggggtgtttggccgagtcctcaccgccttctcccgggaacctgacaaccccaaggtgtgagaccctgagggcgcaatgg taacctgaagatagggagagaggggaggactcgcgctctccagcggggcacaccaaccacggccctcccgtggcctccca cgaccactcagccacccctgcacactctggcccacccttgtgccccggcccctctaggccccgcctcctcccgcccctgc cccgcccctttggctctgccctgttgacaacgccccagggcacgcaggccccaccaggcccgctccggagaatttcaagg tccagggccagccagcagccccgggctgcccccgcgcccacccccaccagggcccgccctaaccccgccgccccgcagac ctacgtgcaggacatcctgaggacggagctggctgcggaggtgcaccgcgtgctgtgcctcgagcggggccacatgtttg tctgcggcgatgttaccatggcaaccaacgtcctgcagaccgtgcagcgcatcctggcgacggagggcgacatggagctg gacgaggccggcgacgtcatcggcgtgctgcgggtgcggaggggcgggccgggcctgagcgtgcggggttcctgctaagg tctccgagtcgggttctgatccactgtgctcttttccgacaggatcagcaacgctaccacgaagacattttcgggctcac gctgcgcacccaggaggtgacaagccgcatacgcacccagagcttttccttgcaggagcgtcagttgcggggcgcagtgc cctgggcgttcgaccctcccggctcagacaccaacagcccctgagagccgcctggctttcccttccagttccgggagagc ggctgcccgactcaggtccgcccgaccaggatcagccccgctcctcccctcttgaggtggtgccttctcacatctgtcca gaggctgcaaggattcagcattattcctccaggaaggagcaaaacgcctcttttccctctctaggcctgttgcctcgggc ctgggtccgccttaatctggaaggcccctcccagcagcggtaccccagggcctactgccacccgcttcctgtttcttagt cgaatgttagattcctcttgcctctctcaggagtatcttacctgtaaagtctaatctctaaatcaagtatttattattga agatttaccataagggactgtgccagatgttaggagaac actaaagtgcctaccccagctcatgtggattacagttttt tttttttgtttttttttttttgaaacggagtctccctctgccgcccgggctggagtgcagtggcgtgatctcagctcact gcaacctccaccccacaagttcaagtgattctcctgcctcagcctcccaagtagttgggattacaggtgcctgccaccgc gcccggctaggttttgtatttttagtaaagacggggtttcaccatcttggccaggctggtcttgaactcctgacctcgtg atccaaccgcctcagcctcccaaagtgctgggattacaggtgtgagctactgcacccggcgtggattacaattataaaat gacaagatttctgttttaacctgtgcagttgtgggtatgtggtggggaaagggg cattcttttaacagagtcctacacg ccacttgaccctgcactctgaaaacatggtttccagccagtctgggctgctcccccgtgcagttctcaggctcgtaatcg agaaggcaggtgcagcactcagctgccaggagtggggcctgccagaaacaagagtcacagagatgtgcaacagccatgag caagcttcagagtggacgcacagtaacatgggcaacttgaagagcgtggcccaggagcctgggccaccctgcggcctggg gctggggctgggccttgggctgtgcggcaagcagggcccagccaccccggcccctgagcccagccgggccccagcatccc tactcccaccagcgccagaacacagccccccgagctccccgctaacccagcccccagaggggcccaagttccctcgtgtg aagaactgggaggtggggagcatcacctatgacaccctcagcgcccaggcgcagcaggatgggccctgcaccccaagacg ctgcctgggctccctggtatttccacggaaactacagggccggccctcccccggccccccggcccctgagcagctgctga gtcaggcccgggacttcatcaaccagtactacagctccattaagaggagcggctcccaggcccacgaacagcggcttcaa gaggtggaagccgaggtggcagccacaggcacctaccagcttagggagagcgagctggtgttcggggctaagcaggcctg gcgcaacgctccccgctgcgtgggccggatccagtgggggaagctgcaggtgttcgatgcccgggactgcaggtctgcac aggaaatgttcacctacatctgcaaccacatcaagtatgccaccaaccggggcaaccttcgctcggccatcacagtgttc ccgcagcgctgccctggccgaggagacttccgaatctggaacagccagctggtgcgctacgcgggctaccggcagcagga cggctctgtgcggggggacccagccaacgtggagatcaccgagctctgcattcagcacggctggaccccaggaaacggtc gcttcgacgtgctgcccctgctgctgcaggccccagatgagcccccagaactcttccttctgccccccgagctggtcctt gaggtgcccctggagcaccccacgctggagtggtttgcagccctgggcctgcgctggtacgccctcccggcagtgtccaa catgctgctggaaattgggggcctggagttccccgcagcccccttcagtggctggtacatgagcactgagatcggcacga ggaacctgtgtgaccctcaccgctacaacatcctggaggatgtggctgtctgcatggacctggatacccggaccacctcg tccctgtggaaagacaaggcagcagtggaaatcaacgtggccgtgctgcacagttaccagctagccaaagtcaccatcgt ggaccaccacgccgccacggcctctttcatgaagcacctggagaatgagcagaaggccagggggggctgccctgcagact gggcctggatcgtgccccccatctcgggcagcctcactcctgttttccatcaggagatggtcaactatttcctgtccccg gccttccgctaccagccagacccctggaaggggagtgccgccaagggcaccggcatcaccaggaagaagacctttaaaga agtggccaacgccgtgaagatctccgcctcgctcatgggcacggtgatggcgaagcgagtgaaggcgacaatcctgtatg gctccgagaccggccgggcccagagctacgcacagcagctggggagactcttccggaaggcttttgatccccgggtcctg tgtatggatgagtatgacgtggtgtccctcgaacacgagacgctggtgctggtggtaaccagcacatttgggaatgggga tcccccggagaatggagagagctttgcagctgccctgatggagatgtccggcccctacaacagctcccctcggccggaac agcacaagagttataagatccgcttcaacagcatctcctgctcagacccactggtgtcctcttggcggcggaagaggaag gagtccagtaacacagacagtgcaggggccctgggcaccctcaggttctgtgtgttcgggctcggctcccgggcataccc ccacttctgcgcctttgctcgtgccgtggacacacggctggaggaactgggcggggagcggctgctgcagctgggccagg gcgacgagctgtgcggccaggaggaggccttccgaggctgggcccaggctgccttccaggccgcctgtgagaccttctgt gtgggagaggatgccaaggccgccgcccgagacatcttcagccccaaacggagctggaagcgccagaggtaccggctgag cgcccaggccgagggcctgcagttgctgccaggtctgatccacgtgcacaggcggaagatgttccaggctacaatccgct cagtggaaaacctgcaaagcagcaagtccacgagggccaccatcctggtgcgcctggacaccggaggccaggaggggctg cagtaccagccgggggaccacataggtgtctgcccgcccaaccggcccggccttgtggaggcgctgctgagccgcgtgga ggacccgccggcgcccactgagcccgtggcagtagagcagctggagaagggcagccctggtggccctccccccggctggg tgcgggacccccggctgcccccgtgcacgctgcgccaggctctcaccttcttcctggacatcacctccccacccagccct cagctcttgcggctgctcagcaccttggcagaagagcccagggaacagcaggagctggaggccctcagccaggatccccg acgctacgaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcagttcccgtcggtggcgctgcctg ccccactgctcctcacccagctgcctctgctccagccccggtactactcagtcagctcggcacccagcacccacccagga gagatccacctcactgtagctgtgctggcatacaggactcaggatgggctgggccccctgcactatggagtctgctccac gtggctaagccagctcaagcccggagaccctgtgccctgcttcatccggggggctccctccttccggctgccacccgatc ccagcttgccctgcattctggtgggtccaggcactggcattgcccccttccggggattctggcaggagcggctgcatgac attgagagcaaagggctgcagcccactcccatgactttggtgttcggctgccgatgctcccaacttgaccatctctaccg cgacgaggtgcagaacgcccagcagcgcggggtgtttggccgagtcctcaccgccttctcccgggaacctgacaacccca agacctacgtgcaggacatcctgaggacggagctggctgcggaggtgcaccgcgtgctgtgcctcgagcggggccacatg tttgtctgcggcgatgttaccatggcaaccaacgtcctgcagaccgtgcagcgcatcctggcgacggagggcgacatgga gctggacgaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaagacattttcgggctcacgctgc gcacccaggaggtgacaagccgcatacgcacccagagcttttccttgcaggagcgtcagttgcggggcgcagtgccctgg gcgttcgaccctcccggctcagacaccaacagcccctgagagccgcctggctttcccttccagttccgggagagcggctg cccgactcaggtccgcc (SEQ ID NO: 12218) aggagtttcgacccgcgctggcgagtcatgagcgccaagtttcccactggcgcgcaaacttgagttacttttgagcgtgg atactggcgaagaggctgcgggcggt ttagcgtttgcagcgacttggctcgggcagctgacccaagtgtcctgtcttcc ttcctctgcttgtctctaggctctgaaactgcggagcggccaccggacgccttctggagcaggtagcagcatgcagccgc ctccaagtctgtgcggaccggccctggttgcgctggttcttgcctgcggcctgtcgcggatctggggagaggagagaggc ttcccgcctgacagggccactccgcttttgcaaaccgcagagataatgacgccacccactaagaccttatggcccaaggg ttccaacgccagtctggcgcggtcgttggcacctgcggaggtgcctaaaggagacaggacggcaggatctccgccacgca ccatctcccctcccccgtgccaaggacccatcgagatcaaggagactttcaaatacatcaacacggttgtgtcctgcctt gtgttcgtgctggggatcatcgggaactccacacttctgagaattatctacaagaacaagtgcatgcgaaacggtcccaa tatcttgatcgccagcttggctctgggagacctgctgcacatcgtcattgacatccctatcaatgtctacaagctgctgg cagaggactggccatttggagctgagatgtgtaagctggtgcctttcatacagaaagcctccgtgggaatcactgtgctg agtctatgtgctctgagtattgacagatatcgagctgttgcttcttggagtagaattaaaggaattggggttccaaaatg gacagcagtagaaattgttttgatttgggtggtctctgtggttctggctgtccctgaagccataggttttgatataatta cgatggactacaaaggaagttatctgcgaatctgcttgcttcatcccgttcagaagacagctttcatgcagttttacaag acagcaaaagattggtggctattcagtttctatttctgcttgccattggccatcactgcatttttttatacactaatgac ctgtgaaatgttgagaaagaaaagtggcatgcagattgctttaaatgatcacctaaagcagagacgggaagtggccaaaa ccgtcttttgcctggtccttgtctttgccctctgctggcttccccttcacctcagcaggattctgaagctcactct tat aatcagaatgatcccaatagatgtgaacttttgagctttctgttggtattggactatattggtatcaacatggcttcact gaattcctgcattaacccaattgctctgtatttggtgagcaaaagattcaaaaactgctttaagtcatgcttatgctgct ggtgccagtcatttgaagaaaaacagtccttggaggaaaagcagtcgtgcttaaagttcaaagctaatgatcacggatat gacaacttccgttccagtaataaatacagctcatcttgaaagaagaactattcactgtatttcattttctttatattgga ccgaagtcattaaaacaaaatgaaacatttgccaaaacaaaacaaaaaactatgtatttgcacagcacactattaaaata ttaagtgtaattattttaacactcacagctacatatgacattttatgagctgtttacggcatggaaagaaaatcagtggg aattaagaaagcctcgtcgtgaaagcacttaattttttacagttagcacttcaacatagctcttaacaacttccaggata ttcacacaacacttaggcttaaaaatgagctc (SEQ ID NO: 12219) gagacattccggtgggggactctggccagcccgagcaacgtggatcctgagagcactcccaggtaggcatttgccccggt gggacgccttgccagagcagtgtgtggcaggcccccgtggaggatcaacacagtggctgaacactgggaaggaactggta cttggagtctggacatctgaaacttggctctgaaactgcgcagcggccaccggacgccttctggagcaggtagcagcatg cagccgcctccaagtctgtgcggacgcgccctggttgcgctggttcttgcctgcggcctgtcgcggatctggggagagga gagaggcttcccgcctgacagggccactccgcttttgcaaaccgcagagataatgacgccacccactaagaccttatggc ccaagggttccaacgccagtctggcgcggtcgttggcacctgcggaggtgcctaaaggagacaggacggcaggatctccg ccacgcaccatctcccctcccccgtgccaaggacccatcgagatcaaggagactttcaaatacatcaacacggttgtgtc ctgccttgtgttcgtgctggggatcatcgggaactccacacttctgagaattatctacaagaacaagtgcatgcgaaacg gtcccaatatcttgatcgccagcttggctctgggagacctgctgcacatcgtcattgacatccctatcaatgtctacaag ctgctggcagaggactggccatttggagctgagatgtgtaagctggtgcctttcatacagaaagcctccgtgggaatcac tgtgctgagtctatgtgctctgagtattgacagatatcgagctgttgcttcttggagtagaattaaaggaattggggttc caaaatggacagcagtagaaattgttttgatttgggtggtctctgtggttctggctgtccctgaagccataggttttgat ataattacgatggactacaaaggaagttatctgcgaatctgcttgct catcccgttcagaagacagctttcatgcagtt ttacaagacagcaaaagattggtggctgttcagtttctatttctgcttgccattggccatcactgcatttttttatacac taatgacctgtgaaatgttgagaaagaaaagtggcatgcagattgctttaaatgatcacctaaagcagagacgggaagtg gccaaaaccgtcttttgcctggtccttgtctttgccctctgctggcttccccttcacctcagcaggattctgaagctcac tctttataatcagaatgatcccaatagatgtgaacttttgagctttctgttggtattggactatattggtatcaacatgg cttcactgaattcctgcattaacccaattgctctgtatttggtgagcaaaagattcaaaaactgctttaagtcatgctta tgctgctggtgccagtcatttgaagaaaaacagtccttggaggaaaagcagtcgtgcttaaagttcaaagctaatgatca cggatatgacaacttccgttccagtaataaatacagctcatcttgaaagaagaactattcactgtatttcattttcttta tattggaccgaagtcattaaaacaaaatgaaacatttgccaaaacaaaacaaaaaactatgtatttgcacagcacactat taaaatattaagtgtaattattttaacactcacagctacatatgacattttatgagctgtttacggcatggaaagaaaat cagtgggaattaagaaagcctcgtcgtgaaagcacttaattttttacagttagcacttcaacatagctcttaacaacttc caggatattcacacaacacttaggcttaaaaatgagctcactcagaatttctattctttctaaaaagagatttattttta aatcaatgggactctgatataaaggaagaataagtcactgtaaaacagaacttttaaatgaagcttaaattactcaattt aaaattttaaaatcctttaaaacaacttttcaattaatattatcacactattatcagattgtaattagatgcaaatgaga gagcagtttagttgttgcatttttcggacactggaaacatttaaatgatcaggagggagtaacagaaagagcaaggctgt ttttgaaaatcattacactttcactagaagcccaaacctcagcattctgcaatatgtaaccaacatgtcacaaacaagca gcatgtaacagactggcacatgtgccagctgaatttaaaatataatacttttaaaaagaaaattattacatcctttacat tcagttaagatcaaacctcacaaagagaaatagaatgtttgaaaggctatcccaaaagacttttttgaatctgtcattca cataccctgtgaagacaatactatctacaattttttcaggattattaaaatcttcttttttcact tcgtagcttaaact ctgtttggttttgtcatctgtaaatacttacctacatacactgcatgtagatgattaaatgagggcaggccctgtgctca tagctttacgatggagagatgccagtgacctcataataaagactgtgaactgcctggtgcagtgtccacatgacaaaggg gcaggtagcaccctctctcacccatgctgtggttaaaatggtttctagcatatgtataatgctatagttaaaatactatt tttcaaaatcatacagattagtacatttaacagctacctgtaaagcttattactaatttttgtattatttttgtaaatag ccaatagaaaagtttgcttgacatggtgcttttctttcatctagaggcaaaactgctttttgagaccgtaagaacctctt agctttgtgcgttcctgcctaatttttatatcttctaagcaaagtgccttaggatagcttgggatgagatgtgtgtgaaa gtatgtacaagagaaaacggaagagagaggaaatgaggtggggttggaggaaacccatggggacagattcccattcttag cctaacgttcgtcattgcctcgtcacatcaatgcaaaaggtcctgattttgttccagcaaaacacagtgcaatgttctca gagtgactttcgaaataaattgggcccaagagctttaactcggtcttaaaatatgcccaaatttttactttgtttttctt ttaataggctgggccacatgttggaaataagctagtaatgttgttttctgtcaatattgaatgtgatggtacagtaaacc aaaacccaacaatgtggccagaaagaaagagcaataataattaattcacacaccatatggattctatttataaatcaccc acaaacttgttctttaatttcatcccaatcactttttcagaggcctgttatcatagaagtcattttagactctcaatttt aaattaattttgaatcactaatattttcacagtttattaatatatttaatttctatttaaattttagattatttttatta ccatgtactgaatttttacatcctgataccctttccttctccatgtcagtatcatgttctctaattatcttgccaaattt tgaaactacacacaaaaagcatacttgcattatttataataaaattgcattcagtggctttttaaaaaaaatgtttgatt caaaactttaacatactgataagtaagaaacaattataatttctttaca actcaaaaccaagatagaaaaaggtgctat cgttcaacttcaaaacatgtttcctagtattaaggactttaatatagcaacagacaaaattattgttaacatggatgtta cagctcaaaagatttataaaagattttaacctattttctcccttattatccactgctaatgtggatgtatgttcaaacac cttttagtattgatagcttacatatggccaaaggaatacagtttatagcaaaacatgggtatgctgtagctaactttata aaagtgtaatataacaatgtaaaaaattatatatctgggaggattttttggttgcctaaagtggctatagttactgattt tttattatgtaagcaaaaccaataaaaatttaagtttttttaacaactaccttatttttcactgtacagacactaattca ttaaatactaattgattgtttaaaagaaatataaatgtgacaagtggacattatttatgttaaatatacaattatcaagc aagtatgaagttattcaattaaaatgccacatttctggtctctggg (SEQ ID NO:12220) gggctgcaggtttcgacccgcgctggcgagtcatgagcgccaagtttcccactggcgcgcaaacttgagttacttttgag cgtggatactggcgaagaggctgcgggcggtattagcgtttgcagcgacttggctcgggcagctgaccccaaagtgtctg tcttccttcctctgcttgtctctaggctctgaaactgcggcggccaccggacgcttctggagcaggtagcagcatgcagc cgcctccaagtctgtgcggacgcgccctggttgcgctggttcttgcctgcggcctgtcgcggatctggggagaggagaga ggcttcccgcccgacagggccactccgcttttgcaaaccgcagagataatgacgccacccactaagaccttatggcccaa gggttccaacgccagtctggcgcggtcgttggcacctgcggaggtgcctaaaggagacaggacggcaggatctccgccac gcaccatctcccctcccccgtgccaaggacccatcgagatcaaggagactttcaaatacatcaacacggttgtgtcctgc cttgtgttcgtgctggggatcatcgggaactccacacttctgagaattatctacaagaacaagtgcatgcgaaacggtcc caatatcttgatcgccagcttggctctgggagacctgctgcacatcgtcattgacatccctatcaatgtctacaagctgc tggcagaggactggccatttggagctgagatgtgtaagctggtgcctttcatacagaaagcctccgtgggaatcactgtg ctgagtctatgtgctctgagtattgacagatatcgagctgttgcttcttggagtagaattaaaggaattggggttccaaa atggacagcagtagaaattgttttgatttgggtggtctctgtggttctggctgtccctgaagccataggttttgatataa ttacgatggactacaaaggaagtta ctgcgaatctgcttgcttcatcccgttcagaagacagctttcatgcagttttac aagacagcaaaagattggtggctgttcagtttctatttctgcttgccattggccatcactgcatttttttatacactaat gacctgtgaaatgttgagaaagaaaagtggcatgcagattgctttaaatgatcacctaaagcagagacgggaagtggcca aaaccgtcttttgcctggtccttgtctttgccctctgctggcttccccttcacctcagcaggattctgaagctcactctt tataatcagaatgatcccaatagatgtgaacttttgagctttctgttggtattggactatattggtatcaacatggcttc actgaattcctgcattaacccaattgctctgtatttggtgagcaaaagattcaaaaactgctttaagtcatgcttatgct gctggtgccagtcatttgaagaaaaacagtccttggaggaaaagcagtcgtgcttaaagttcaaagctaatgatcacgga tatgacaacttccgttccagtaataaatacagctca cttgaaagaagaactattcactgtatttcattttctttatatt ggaccgaagtcattaaaacaaaatgaaacatttgccaaaacaaaacaaaaaactatgtatttgcacagcacactattaaa atattaagtgtaattattttaaaaaaaaaaaaaaaaaaa (SEQ ID NO: 12221) cccactatgttggccaggatggtcttgatttcttgacctcgtgttctgcccgcctctacctcccaaagtgccgggattac aggcgtgactgctgtgcccggccccagcatcacttttatagctttctgtgcctcttcctctgggccttggtgtatgaagc cacttgcctttctctgttgggaagcgagcagaatcagattgctactcatgatgcagtccgggcagggcatactgtcacct ttggctgtggacacagttgtcaggataggggagaagccctttaggtccgtcttcttgacacagccctcctacctggttac gctggtgctttcgcttggtttagacaaccaagacacttgagaattatgctgtcctcagaatgtctgatgaaaagaacaga ttcactttttggacacaatgcccattagccatctttggcagtgtttctgatcaaaggttccccatgcctgctctaggaaa gtaaacttttttcagaataaatcctcaaatggattactgagtagtctttgcaccattcccatcagcctaatcagactgaa tggtcacgctcagtgcaaaaagctgttttgctgttaggatgtttcagtgtttcttgtctttcctggaacagttcagttgt ttaaatttagtaattcaatcctgaccagtgtaaacccacttaattattgcagcctaaagaattcagctacttctactctt cataaatgtgcccaagtaaatatgtgtttttaatattcaaccctggaaaattagtaattcagatgataaaagctcatgtt ttggtgtctttgtactcagattgtgaacaggcatatttcactgatttagacttagtatacttgatgagaatgctcaggtt gaagagatagttctgtcagcaatccaacatctatagcaatgtggaaaaagtaatcaactcatatttcacgaatttgatgt atgttgtgatttagagggcatgagataaagtttatatttgaactgtgtggggtagggggaagaagaggttgcttaagcaa atgggggggtgattgaggaacaagatgtctctaagatgagaagttattttcttgcatcatagaagcactctythyacccg ngagtgattgtgttaactataaatcatt atatctgtacattaaagcagattccctcaattaggcaaatttggttagcca agcccaagttattgtttgtact gaaagtaataaagctgcatttccttaaaaatatattctgtagttaagactttgtctt gctttccggaattcctgtttttcttttcctctagagacctcggcttgcaactggatcaaacgctgtcgaaaggatgtaaa taggcagagcaactgttaccaagaaggccaccacccccacccaaaggcagtgaggagtgtggggcttcgtctgggc ccc ccgagtctcaacagtaatcaacagtcaggtgttgattgcaacttttcaaggtcagccaccgggagtagcctattccctct aggaaccttggagggcataccttgctgggactcaacttggctgagaaatgcacaagatgccaaaggaggaaggattatag ggggcgtgtgtgtgacccccaagaccgatcttccgctatcaccctaatctccggttccccgctacccgggcgggggtgag tatgtgacatgtgcctaactctcagcagcaacttcggcagcaggtgtcgatcctaactaagcaggagctgcggctgccgg gtgtgccctcaccaagccatgcgagccccgggcgcgcttctcgcccgcatgtcgcggctactgcttctgctactgctcaa ggtgtctgcctcttctgccctcggggtcgcccctgcgtccagaaacgaaacttgtctgggggagagctgtgcacctacag tgatccagcgccgcggcagggacgcctggggaccgggaaattctgcaagagacgttctgcgagcccgagcacccagggag gagcagggggcagcgtttcttgcgggaccctcctgggacctgccggcggccccggaccgtgacccggctgcaggcagagg ggcggaggcgtcgacagccggacccccgggacctccaaccaggccacctgtcccctggaggtggaaaggtgctcggggtc aggagccttctgaaactttggggagagggaaccccacggccctccagctcttccttcagatctcagaggaggaagagaag ggtcccagaggcgctgtcatttccgggcgtagccaggagσagagtgtgaagacagtccccggagccagcgatctttttta ctgtccaaggagagccgggaaactccagggttcccaccacaagcccctgtccaagacggccaatggactggcggggcacg aagggtggacaattgcactcccgggccgggcgctggcccagaatggatccttgggtgaaggaatccatgatcctgggggt ccccgccggggaaacagcacgaaccggcgtgtgagactgaagaaccccttctacccgctgacccaggagtcctatggagc ctacgcggtcatgtgtctgtccgtggtgatcttcgggaccggcatcattggcaacctggcggtgatgtgcatcgtgtgcc acaactactacatgcggagcatctccaactccctcttggccaacctggtcttctgggactttctcatcatcttcttctgc cttccgctggtcatcttccacgagctgaccaagaagtggctggtggaggacttctcctgcaagatcgtgccctatataga ggtcgcttctctgggagtcaccactttcaccttatgtgctctgtgcatagaccgcttccgtgctgccaccaacgtacaga tgtactacgaaatgatcgaaaactgttcctcaacaactgccaaacttgctgttatatgggtgggagctctattgttagca cttccagaagttgttctccgccagctgagcaaggaggatttggggtttagtggccgagctccggcagaaaggtgcattat taagatctctcctgatttaccagacaccatctatgttctagccctcacctacgacagtgcgagactgtggtggtattttg gctgttacttttgtttgcccacgcttttcaccatcacctgctctctagtgactgcgaggaaaatccgcaaagcagagaaa gcctgtacccgagggaataaacggcagattcaactagagagtcagatgaactgtacagtagtggcactgaccattttata tggattgggcattattcctgaaaat tctgcaacattgttactgcctacatggctacaggggtttcacagcagacaatgg acctccttaatatcatcagccagttccttttgttctttaagtcctgtgtcaccccagtcctccttttctgtctctgcaaa cccttcagtcgggccttcatggagtgctgctgctgttgctgtgaggaatgcattcagaagtcttcaacggtgaccagtga tgacaatgacaacgagtacaccacggaactcgaactctcgcctttcagtgccatacgccgtgaaatgtccacttttgctt ctgtcggaactcattgctgaaggacagtacttggttgggtcagatttatttgtttgattttcatatcccgtgaaagtttt taattcatatttttccttatagggaaaaatgcaaaaaagaaacaataaagaaagaaatattaactactgtagaactgatt ttacaaattaatatttgtgctttgaaaaaaagtttctatttagttatttaagaagaatgagaaggccaatagttttagat tattttatctggtatggtgctaatattttatttgaaaaaagttactgcaacttaacttaaaattgctaacgttttttctt cttttaaaaatacaattattgtatattaattatagcaatgtgattttgtaggttattttatatttgagttgtgattgaaa gtatgttgtatatggtattgtgagatgatttgtacttggaagcattcacaaagtagcaccaaataaattacactttattc tttaatgtcattgtcaatctacttttaaccaatattcaataaatcttctaattgccttaaaaaaaaaaaaaaaaaa (SEQ ID NO: 12222) gggctgcaggtttcgacccgcgctggcgagtcatgagcgccaagtttcccactggcgcgcaaacttgagttacttttgag cgtggatactggcgaagaggctgcgggcggtattagcgtttgcagcgacttggctcgggcagctgaccccaaagtgtctg tcttccttcctctgcttgtctctaggctctgaaactgcggcggccaccggacgcttctggagcaggtagcagcatgcagc cgcctccaagtctgtgcggacgcgccctggttgcgctggttcttgcctgcggcctgtcgcggatctggggagaggagaga ggcttcccgcccgacagggccactccgcttttgcaaaccgcagagataatgacgccacccactaagaccttatggcccaa gggttccaacgccagtctggcgcggtcgttggcacctgcggaggtgcctaaaggagacaggacggcaggatctccgccac gcaccatctcccctcccccgtgccaaggacccatcgagatcaaggagactttcaaatacatcaacacggttgtgtcctgc cttgtgttcgtgctggggatcatcgggaactccacacttctgagaattatctacaagaacaagtgcatgcgaaacggtcc caatatcttgatcgccagcttggctctgggagacctgctgcacatcgtcattgacatccctatcaatgtctacaagctgc tggcagaggactggccatttggagctgagatgtgtaagctggtgcctt catacagaaagcctccgtgggaatcactgtg ctgagtctatgtgctctgagtattgacagatatcgagctgttgcttcttggagtagaattaaaggaattggggttccaaa atggacagcagtagaaattgttttgatttgggtggtctctgtggttctggctgtccctgaagccataggttttgatataa ttacgatggactacaaaggaagttatctgcgaatctgcttgcttcatcccgttcagaagacagctttcatgcagttttac aagacagcaaaagattggtggctgttcagtttctatttctgcttgccattggccatcactgcattttt tatacactaat gacctgtgaaatgttgagaaagaaaagtggcatgcagattgctttaaatgatcacctaaagcagagacgggaagtggcca aaaccgtcttttgcctggtccttgtctttgccctctgctggcttccccttcacctcagcaggattctgaagctcactctt tataatcagaatgatcccaatagatgtgaacttttgagctttctgttggtattggactatattggtatcaacatggcttc actgaattcctgcattaacccaattgctctgtatttggtgagcaaaagattcaaaaactgctttaaggctgggccacatg ttggaaataagctagtaatgttgttttctgtcaatattgaatgtgatggtacagtaaaccaaaacccaacaatgtggcca gaaagaaagagcaataataattaattcacacaccatatggattctatttataaatcac (SEQ ID NO: 12223) aggagtttcgacccgcgctggcgagtcatgagcgccaagtttcccactggcgcgcaaacttgagttacttttgagcgtgg atactggcgaagaggctgcgggcggtattagcgtttgcagcgacttggctcgggcagctgacccaagtgtcctgtcttcc ttcctctgcttgtctctaggctctgaaactgcggagcggccaccggacgccttctggagcaggtagcagcatgcagccgc ctccaagtctgtgcggaccggccctggttgcgctggttcttgcctgcggcctgtcgcggatctggggagaggagagaggc ttcccgcctgacagggccactccgcttttgcaaaccgcagagataatgacgccacccactaagaccttatggcccaaggg ttccaacgccagtctggcgcggtcgttggcacctgcggaggtgcctaaaggagacaggacggcaggatctccgccacgca ccatctcccctcccccgtgccaaggacccatcgagatcaaggagactttcaaatacatcaacacggttgtgtcctgcctt gtgttcgtgctggggatcatcgggaactccacacttctgagaattatctacaagaacaagtgcatgcgaaacggtcccaa tatcttgatcgccagcttggctctgggagacctgctgcacatcgtcattgacatccctatcaatgtctacaagctgctgg cagaggactggccatttggagctgagatgtgtaagctggtgcctttcatacagaaagcctccgtgggaatcactgtgctg agtctatgtgctctgagtattgacagatatcgagctgttgcttcttggagtagaattaaaggaattggggttccaaaatg gacagcagtagaaattgttttgatttgggtggtctctgtggttctggctgtccctgaagccataggttttgatataatta cgatggactacaaaggaagttatctgcgaatctgcttgcttcatcccgttcagaagacagctttcatgcagttttacaag acagcaaaagattggtggctattcagtttctatttctgcttgccattggccatcactgcatttttttatacactaatgac ctgtgaaatgttgagaaagaaaagtggcatgcagattgctttaaatgatcacctaaagcagagacgggaagtggccaaaa ccgtcttttgcctggtccttgtctttgccctctgctggcttccccttcacctcagcaggattctgaagctcactctttat aatcagaatgatcccaatagatgtgaacttttgagctttctgttggtattggactatattggtatcaacatggcttcact gaattcctgcattaacccaattgctctgtatttggtgagcaaaagattcaaaaactgctttaagtcatgcttatgctgct ggtgccagtcatttgaagaaaaacagtccttggaggaaaagcagtcgtgcttaaagttcaaagctaatgatcacggatat gacaacttccgttccagtaataaatacagctcatcttgaaagaagaactattcactgtatttcattttct tatattgga ccgaagtcattaaaacaaaatgaaacatttgccaaaacaaaacaaaaaactatgtatttgcacagcacactattaaaata ttaagtgtaattattttaacactcacagctacatatgacattttatgagctgtttacggcatggaaagaaaatcagtggg aattaagaaagcctcgtcgtgaaagcacttaattttttacagttagcacttcaacatagctcttaacaacttccaggata ttcacacaacacttaggcttaaaaatgagctcgagacattccggtgggggactctggccagcccgagcaacgtggatcct gagagcactcccaggtaggcatttgccccggtgggacgccttgccagagcagtgtgtggcaggcccccgtggaggatcaa cacagtggctgaacactgggaaggaactggtacttggagtctggacatctgaaacttggctctgaaactgcgcagcggcc accggacgccttctggagcaggtagcagcatgcagccgcctccaagtctgtgcggacgcgccctggttgcgctggttctt gcctgcggcctgtcgcggatctggggagaggagagaggcttcccgcctgacagggccactccgcttttgcaaaccgcaga gataatgacgccacccactaagaccttatggcccaagggttccaacgccagtctggcgcggtcgttggcacctgcggagg tgcctaaaggagacaggacggcaggatctccgccacgcaccatctcccctcccccgtgccaaggacccatcgagatcaag gagactttcaaatacatcaacacggttgtgtcctgccttgtgttcgtgctggggatcatcgggaactccacacttctgag aattatctacaagaacaagtgcatgcgaaacggtcccaatatcttgatcgccagcttggctctgggagacctgctgcaca tcgtcattgacatccctatcaatgtctacaagctgctggcagaggactggccatttggagctgagatgtgtaagctggtg cctttcatacagaaagcctccgtgggaatcactgtgctgagtctatgtgctctgag attgacagatatcgagctgttgc ttcttggagtagaattaaaggaattggggttccaaaatggacagcagtagaaattgttttgatttgggtggtctctgtgg ttctggctgtccctgaagccataggttttgatataattacgatggactacaaaggaagttatctgcgaatctgcttgctt catcccgttcagaagacagctttcatgcagttttacaagacagcaaaagattggtggctgttcagtttctatttctgctt gccattggccatcactgcatttttttatacactaatgacctgtgaaatgttgagaaagaaaagtggcatgcagattgctt taaatgatcacctaaagcagagacgggaagtggccaaaaccgtcttttgcctggtccttgtctttgccctctgctggctt ccccttcacctcagcaggattctgaagctcactctttataatcagaatgatcccaatagatgtgaacttttgagctttct gttggtattggactatattggtatcaacatggcttcactgaattcctgcattaacccaattgctctgtatttggtgagca aaagattcaaaaactgctttaagtcatgcttatgctgctggtgccagtcatttgaagaaaaacagtccttggaggaaaag cagtcgtgcttaaagttcaaagctaatgatcacggatatgacaacttccgttccagtaataaatacagctcatcttgaaa gaagaactattcactgtatttcattttctttatattggaccgaagtcattaaaacaaaatgaaacatttgccaaaacaaa acaaaaaactatgtatttgcacagcacactattaaaatattaagtgtaattattttaacactcacagctacatatgacat tttatgagctgtttacggcatggaaagaaaatcagtgggaattaagaaagcctcgtcgtgaaagcacttaattttttaca gttagcacttcaacatagctcttaacaacttccaggatattcacacaacacttaggcttaaaaatgagctcactcagaat ttctattctttctaaaaagagatttatttttaaatcaatgggactctgatataaaggaagaataagtcactgtaaaacag aacttttaaatgaagcttaaattactcaatttaaaattttaaaatcctttaaaacaacttttcaattaatattatcacac tattatcagattgtaattagatgcaaatgagagagcagtttagttgttgcatttttcggacactggaaacatttaaatga tcaggagggagtaacagaaagagcaaggctgtttttgaaaatcattacactttcactagaagcccaaacctcagcattct gcaatatgtaaccaacatgtcacaaacaagcagcatgtaacagactggcacatgtgccagctgaatttaaaatataatac ttttaaaaagaaaattattacatcctttacattcagttaagatcaaacctcacaaagagaaatagaatgtttgaaaggct atcccaaaagacttttttgaatctgtcattcacataccctgtgaagacaatactatctacaattttttcaggattattaa aatcttcttttttcactatcgtagcttaaactctgtttggttttgtcatctgtaaatacttacctacatacactgcatgt agatgattaaatgagggcaggccctgtgctcatagctttacgatggagagatgccagtgacctcataataaagactgtga actgcctggtgcagtgtccacatgacaaaggggcaggtagcaccctctctcacccatgctgtggttaaaatggtttctag catatgtataatgctatagttaaaatactatttttcaaaatcatacagattagtacatttaacagctacctgtaaagctt attactaatttttgtattatttttgtaaatagccaatagaaaagtttgcttgacatggtgcttttctttcatctagaggc aaaactgctttttgagaccgtaagaacctcttagctttgtgcgttcctgcctaatttttatatcttctaagcaaagtgcc ttaggatagcttgggatgagatgtgtgtgaaagtatgtacaagagaaaacggaagagagaggaaatgaggtggggttgga ggaaacccatggggacagattcccattcttagcctaacgttcgtcattgcctcgtcacatcaatgcaaaaggtcctgatt ttgttccagcaaaacacagtgcaatgttctcagagtgactttcgaaataaattgggcccaagagctttaactcggtctta aaatatgcccaaatttttactttgtttttcttttaataggctgggccacatgttggaaataagctagtaatgttgttttc tgtcaatattgaatgtgatggtacagtaaaccaaaacccaacaatgtggccagaaagaaagagcaataataattaattca cacaccatatggattctatttataaatcacccacaaacttgttctttaatttcatcccaatcactttttcagaggcctgt tatcatagaagtcattttagactctcaattttaaattaattttgaatcactaatattttcacagtttattaatatattta atttctatttaaattttagattatttttattaccatgtactgaatttttacatcctgataccctttccttctccatgtca gtatcatgttctctaattatcttgccaaattttgaaactacacacaaaaagcatacttgcattatttataataaaattgc attcagtggctttttaaaaaaaatgtttgattcaaaactttaacatactgataagtaagaaacaattataatttctttac atactcaaaaccaagatagaaaaaggtgctatcgttcaacttcaaaacatgtttcctagtattaaggactttaatatagc aacagacaaaattattgttaacatggatgttacagctcaaaagatttataaaagattttaacctattttctcccttatta tccactgctaatgtggatgtatgttcaaacaccttttagtattgatagcttacatatggccaaaggaatacagtttatag caaaacatgggtatgctgtagctaactttataaaagtgtaatataacaatgtaaaaaattatatatctgggaggattttt tggttgcctaaagtggctatagttactgattttttattatgtaagcaaaaccaataaaaatttaagtttttttaacaact accttatttttcactgtacagacactaattcattaaatactaattgattgtttaaaagaaatataaatgtgacaagtgga cattatttatgttaaatatacaattatcaagcaagtatgaagttattcaattaaaatgccacatttctggtctctggggg gctgcaggtttcgacccgcgctggcgagtcatgagcgccaagtttcccactggcgcgcaaacttgagttacttttgagcg tggatactggcgaagaggctgcgggcggtattagcgtttgcagcgacttggctcgggcagctgaccccaaagtgtctgtc ttccttcctctgcttgtctctaggctctgaaactgcggcggccaccggacgcttctggagcaggtagcagcatgcagccg cctccaagtctgtgcggacgcgccctggttgcgctggttcttgcctgcggcctgtcgcggatctggggagaggagagagg cttcccgcccgacagggccactccgcttttgcaaaccgcagagataatgacgccacccactaagaccttatggcccaagg gttccaacgccagtctggcgcggtcgttggcacctgcggaggtgcctaaaggagacaggacggcaggatctccgccacgc accatctcccctcccccgtgccaaggacccatcgagatcaaggagactttcaaatacatcaacacggttgtgtcctgcct tgtgttcgtgctggggatcatcgggaactccacacttctgagaattatctacaagaacaagtgcatgcgaaacggtccca atatcttgatcgccagcttggctctgggagacctgctgcacatcgtcattgacatccctatcaatgtctacaagctgctg gcagaggactggccatttggagctgagatgtgtaagctggtgcctttcatacagaaagcctccgtgggaatcactgtgct gagtctatgtgctctgagtattgacagatatcgagctgttgcttcttggagtagaattaaaggaattggggttccaaaat ggacagcagtagaaattgttttgatttgggtggtctctgtggttctggctgtccctgaagccataggttttgatataatt acgatggactacaaaggaagttatctgcgaatctgcttgcttca cccgttcagaagacagctttcatgcagttttacaa gacagcaaaagattggtggctgttcagtttctatttctgcttgccattggccatcactgcatttttttatacactaatga cctgtgaaatgttgagaaagaaaagtggcatgcagattgctttaaatgatcacctaaagcagagacgggaagtggccaaa accgtcttttgcctggtccttgtctttgccctctgctggcttccccttcacctcagcaggattctgaagctcactcttta taatcagaatgatcccaatagatgtgaacttttgagctttctgttggtattggactatattggtatcaacatggcttcac tgaattcctgcattaacccaattgctctgtatttggtgagcaaaagattcaaaaactgctttaagtcatgcttatgctgc tggtgccagtcatttgaagaaaaacagtccttggaggaaaagcagtcgtgcttaaagttcaaagctaatgatcacggata tgacaacttccgttccagtaataaatacagctcatcttgaaagaagaactattcactgtatttcattttctttatattgg accgaagtcattaaaacaaaatgaaacatttgccaaaacaaaacaaaaaactatgtatttgcacagcacactattaaaat attaagtgtaattattttaaaaaaaaaaaaaaaaaaacccactatgttggccaggatggtcttgatttcttgacctcgtg ttctgcccgcctctacctcccaaagtgccgggattacaggcgtgactgctgtgcccggccccagcatcacttttatagct ttctgtgcctcttcctctgggccttggtgtatgaagccacttgcctttctctgttgggaagcgagcagaatcagattgct actcatgatgcagtccgggcagggcatactgtcacctttggctgtggacacagttgtcaggataggggagaagcccttta ggtccgtcttcttgacacagccctcctacctggttacgctggtgctttcgcttggtttagacaaccaagacacttgagaa ttatgctgtcctcagaatgtctgatgaaaagaacagattcactttttggacacaatgcccattagccatctttggcagtg tttctgatcaaaggttccccatgcctgctctaggaaagtaaacttttttcagaataaatcctcaaatggattactgagta gtctttgcaccattcccatcagcctaatcagactgaatggtcacgctcagtgcaaaaagctgttttgctgttaggatgtt tcagtgtttcttgtctttcctggaacagttcagttgtttaaatttagtaattcaatcctgaccagtgtaaacccacttaa ttattgcagcctaaagaattcagctacttctactcttcataaatgtgcccaa^'gtaaatatgtgtttttaatattcaaccc tggaaaattagtaattcagatgataaaagctcatgttttggtgtctttgtactcagattgtgaacaggcatatttcactg atttagacttagtatacttgatgagaatgctcaggttgaagagatagttctgtcagcaatccaacatctatagcaatgtg gaaaaagtaatcaactcatatttcacgaatttgatgtatgttgtgatttagagggcatgagataaagtttatatttgaac tgtgtggggtagggggaagaagaggttgcttaagcaaatgggggggtgattgaggaacaagatgtctctaagatgagaag ttattttcttgcatcatagaagcactctythyacccgngagtgattgtgttaactataaatcatttatatctgtacatta aagcagattccctcaattaggcaaatttggttagccaagcccaagttattgtttgtacttgaaagtaataaagctgcatt tccttaaaaatatattctgtagttaagactttgtcttgctttccggaattcctgtttttcttttcctctagagacctcgg cttgcaactggatcaaacgctgtcgaaaggatgtaaataggcagagcaactgttaccaagaaggccaccacccccaccca aaggcagtgaggagtgtggggcttcgtctgggctcccccgagtctcaacagtaatcaacagtcaggtgttgattgcaact tttcaaggtcagccaccgggagtagcctattccctctaggaaccttggagggcataccttgctgggactcaacttggctg agaaatgcacaagatgccaaaggaggaaggattatagggggcgtgtgtgtgacccccaagaccgatcttccgctatcacc ctaatctccggttccccgctacccgggcgggggtgagtatgtgacatgtgcctaactctcagcagcaacttcggcagcag gtgtcgatcctaactaagcaggagctgcggctgccgggtgtgccctcaccaagccatgcgagccccgggcgcgcttctcg cccgcatgtcgcggctactgcttctgctactgctcaaggtgtctgcctcttctgccctcggggtcgcccctgcgtccaga aacgaaacttgtctgggggagagctgtgcacctacagtgatccagcgccgcggcagggacgcctggggaccgggaaattc tgcaagagacgttctgcgagcccgagcacccagggaggagcagggggcagcgtttcttgcgggaccctcctgggacctgc cggcggccccggaccgtgacccggctgcaggcagaggggcggaggcgtcgacagccggacccccgggacctccaaccagg ccacctgtcccctggaggtggaaaggtgctcggggtcaggagccttctgaaactttggggagagggaaccccacggccct ccagctcttccttcagatctcagaggaggaagagaagggtcccagaggcgctgtcatttccgggcgtagccaggagcaga gtgtgaagacagtccccggagccagcgatcttttttactgtccaaggagagccgggaaactccagggttcccaccacaag cccctgtccaagacggccaatggactggcggggcacgaagggtggacaattgcactcccgggccgggcgctggcccagaa tggatccttgggtgaaggaatccatgatcctgggggtccccgccggggaaacagcacgaaccggcgtgtgagactgaaga accccttctacccgctgacccaggagtcctatggagcctacgcggtcatgtgtctgtccgtggtgatcttcgggaccggc atcattggcaacctggcggtgatgtgcatcgtgtgccacaactactacatgcggagcatctccaactccctcttggccaa cctggtcttctgggactttctcatcatcttcttctgccttccgctggtcatcttccacgagctgaccaagaagtggctgg tggaggacttctcctgcaagatcgtgccctatatagaggtcgcttctctgggagtcaccactttcaccttatgtgctctg tgcatagaccgcttccgtgctgccaccaacgtacagatgtactacgaaatgatcgaaaactgttcctcaacaactgccaa acttgctgttatatgggtgggagctctattgttagcacttccagaagttgttctccgccagctgagcaaggaggatttgg ggtttagtggccgagctccggcagaaaggtgcattattaagatctctcctgatttaccagacaccatctatgttctagcc ctcacctacgacagtgcgagactgtggtggtattttggctgttacttttgtttgcccacgcttttcaccatcacctgctc tctagtgactgcgaggaaaatccgcaaagcagagaaagcctgtacccgagggaataaacggcagattcaactagagagtc agatgaactgtacagtagtggcactgaccattttatatggattgggcattattcctgaaaatatctgcaacattgttact gcctacatggctacaggggtttcacagcagacaatggacctccttaatatcatcagccagttccttttgttctttaagtc ctgtgtcaccccagtcctccttttctgtctctgcaaacccttcagtcgggccttcatggagtgctgctgctgttgctgtg aggaatgcattcagaagtcttcaacggtgaccagtgatgacaatgacaacgagtacaccacggaactcgaactctcgcct ttcagtgccatacgccgtgaaatgtccacttttgcttctgtcggaactcattgctgaaggacagtacttggttgggtcag atttatttgtttgattttcatatcccgtgaaagtttttaattcatatttttccttatagggaaaaatgcaaaaaagaaac aataaagaaagaaatattaactactgtagaactgattttacaaattaatatttgtgctttgaaaaaaagtttctatttag ttatttaagaagaatgagaaggccaatagttttagattattttatctggtatggtgctaatattttatttgaaaaaagtt actgcaacttaacttaaaattgctaacgttttttcttcttttaaaaatacaattattgtatattaattatagcaatgtga ttttgtaggttattttatatttgagttgtgattgaaagtatgttgtatatggtattgtgagatgatttgtacttggaagc attcacaaagtagcaccaaataaattacactttattctttaatgtcattgtcaatctacttttaaccaatattcaataaa tct ctaattgccttaaaaaaaaaaaaaaaaaagggctgcaggtttcgacccgcgctggcgagtcatgagcgccaagttt cccactggcgcgcaaacttgagttacttttgagcgtggatactggcgaagaggctgcgggcggtattagcgtttgcagcg acttggctcgggcagctgaccccaaagtgtctgtcttccttcctctgcttgtctctaggctctgaaactgcggcggccac cggacgcttctggagcaggtagcagcatgcagccgcctccaagtctgtgcggacgcgccctggttgcgctggttcttgcc tgcggcctgtcgcggatctggggagaggagagaggcttcccgcccgacagggccactccgcttttgcaaaccgcagagat aatgacgccacccactaagaccttatggcccaagggttccaacgccagtctggcgcggtcgttggcacctgcggaggtgc ctaaaggagacaggacggcaggatctccgccacgcaccatctcccctcccccgtgccaaggacccatcgagatcaaggag actttcaaatacatcaacacggttgtgtcctgccttgtgttcgtgctggggatcatcgggaactccacacttctgagaat tatctacaagaacaagtgcatgcgaaacggtcccaatatcttgatcgccagcttggctctgggagacctgctgcacatcg tcattgacatccctatcaatgtctacaagctgctggcagaggactggccatttggagctgagatgtgtaagctggtgcct ttcatacagaaagcctccgtgggaatcactgtgctgagtctatgtgctctgagtattgacagatatcgagctgttgcttc ttggagtagaattaaaggaattggggttccaaaatggacagcagtagaaattgttttgatttgggtggtctctgtggttc tggctgtccctgaagccataggttttgatataattacgatggactacaaaggaagttatctgcgaatctgcttgcttcat cccgttcagaagacagctttcatgcagttttacaagacagcaaaagattggtggctgttcagtttctatttctgcttgcc at ggccatcactgcatttttttatacactaatgacctgtgaaatgttgagaaagaaaagtggcatgcagattgctttaa atgatcacctaaagcagagacgggaagtggccaaaaccgtcttttgcctggtccttgtctttgccctctgctggcttccc cttcacctcagcaggattctgaagctcactctttataatcagaatgatcccaatagatgtgaacttttgagctttctgtt ggtattggactatattggtatcaacatggcttcactgaattcctgcattaacccaattgctctgtatttggtgagcaaaa gattcaaaaactgctttaaggctgggccacatgttggaaataagctagtaatgttgttttctgtcaatattgaatgtgat ggtacagtaaaccaaaacccaacaatgtggccagaaagaaagagcaataataattaattcacacaccatatggattctat ttataaatcac (SEQ ID NO: 12224) gatatcctattaatacagagatacagaaagaaatacataaaaaatagttttatcaaatactttccagcattcaagtgtag cctcaaaagcaagaataggccaggagtggtggctcacgctgtaatccacagcactgtgggaggccaaggtaagaggattg cttgaggccaggatttcaagaccagcctaggcaacatagtgagatccctatctctacgaaaaaattttaaaacttagctg ggcatggtgcttgagcctgttgtcccagctactcaggaggtgaagtaggagtgtcacttgagcccaggaggttgaggctg cagtgagctataactgcaccactgcactccagccttggagacagagtgagaccctgtccccaaaaaaattaaaattgaga aaaaaaaaaaggcaagaacagccacagcaaactttctattggggaaaaaaaaaaatcctcctctttacatctctcccttc cttcccttccctttctgagagtgactgtggccaaaaggagcattttccccctgcagtcctctgaggggtggggtggggct atgaagctatccttcatattcactcctttgtccagctcttttcacctctagttcttctccccgcatctctgtctagcagt gccttaagtggaggaggggtgggggcatcaagcttgtaaaactggtttgttggggttctccttctcccctcatttcttga ttcttgggaaaatgtcttgctgggaggctgcctggcgagtgccctagctgccttctgtgggcttgaatggggcttccctc tgcccctacaggaggaaaagggagctgctgccagagggagaaatggagagatggacagagaaggcaggtgccacccctcg cccctgacacacaaagaaaaagacacggaaattctctctctctcttctcttctcctatctctctctctctccctctctct ctctctctctctctctctcacacacacacacacacacacacacacacacacaggcgcgcgccgcgcgcgcaggcacacgt cttgcaaattcaggattcaaagagacaggggcaccattatatttggcacggtggggccttccaggtctgaaatcctgcat tcttccttactatttactttccccgagctcgagaagggccaggtgtgggcggatggctggccacgttttgtgtttccaat tcatattcacgggatgacacagacggggcgtggtgagtgctgttggaggcgcttgggcagtttcattttgccccacttct ccacctgaaggctgggcgttgctggaacctgcaggggcagcctcagcaaggtggggtggcgtggagtggggtgggagaag ggactccagctgaagtagaacccaggctggacctgagaatattggggagggcatgggcggtggtttccgggtaggggcct tgaggacatgttggtcctgactgttgtcagtgtttggtcaaagttgccaaaaggttaaaaaaaaaaaagtagggggagtc cctgccaagacatatttcccaggccacctttcttccgcgggagtgttgggggggaggcgctgcttggaacctgtgaatgt gacatcagctctcctctcctctcccaaggtcggctttggagagggaggtcagggcacccttgcctggcacaggcacgctg gcttccggctcagtgccgcctgctctccgggagctgtgcgctccctgggccccggggctaggctgaggtaagcgcacagc ggaggccaggcgcgccggcagaggcctgggggatagggtggaggcatctctgggtgtgggtgtgggtgtgggtgtgggag ggagagttcttgcctctctctctcccatctccaactcttgcttcagtggctcttttagaggatgcatgtcattatggacc tgtcgctgccactgtccctgttcccccagctgtgacttcgagggaggtctggggatctgagtctgtccaaacccacggct ttgctgttgggataaaaactgtccttttgattttagaaggaggagggaaaaaaggtttcccagcatgtgtgttgtgccag tcttggaaattcatccgtgcttgaattccaccctccatccccagaaaaactggagtaaaacaaaaagaggagatggacaa agtgtgtatttgatggcatcccctgggaagagactctaaatttatcccataggtcttactgggccactgtgagcgctttg gtggagaacaaacaaaaattctgggtgctcagttgtctaacctgaaaaatgggactagcggaaaaagccaatgtgttcca tgcaccttttgctttcttt ttaaggcatgatgtcacctgtacagtaactgccctgtgtgtacttcagggggggatttca aggttagatagacaggaaattgttttgaaaatgtaaacacattattaaatgtgaagtattatctgattccttgttcgaat ggcatttccttctcagcaccaccttccttgcatattcacttaaccttgtacaagaacacctttttgccctaaatgaagac acccccccaaaaaaaagagtcccagaaaatatgtccctgcttgtgcgggaataaatagaatattctgaggtgcattcctc cttcctatgttaggcaacattccttgaccctcctcggcccccaagccaggttgcgtttttttctgccatttagaagggtt ttcctttttgtcctagtaaaacatcagcccctgtagctcttcatctccccctggtgttcttctcccgccatgtcttaaga ttggtggcaccgaccaatcttaagatttaagttctgtgtgaaaaacacctttgcttttcaatcagtttatcagcctcctc cgcaggggaatgtggacacacaaaagaacttatcggggcttctcatcagtgatagggaaaagactggcatgtgcctaaac gagctctgatgttatttttaagctccctttcttgccaatccctcacggatctttctccgatagatgcaaagaacttcagc aaaaaagacccgcaggaaggggcttgaagagaaaagtacgttgatctgccaaaatagtctgacccccagtagtgggcagt gacgagggagagcattcccttgtttgactgagactagaatcggagagacataaaaggaaaatgaagcgagcaacaattaa aaaaaattccccgcacacaacaatacaatctatttaaactgtggctcatacttttcataccaatggtatgactttttttc tggagtcccctcttctgattcttgaactccggggctggcagcttgcaaaggggaagcggactccagcactgcacgggcag gtttagcaaaggtctctaatgggtattttctttttcttagccctgcccccgaattgtcagacggcgggcgtctgcttctg aagttagcagtgatttcctttcgggcctggcttatctccggctgcacgttgcctgttggtgactaataacacaataacat tgtctggggctggaataaagtcggagctgtttac^'ccccactctaataggggttcaatataaaaagccggcagagagctgt ccaagtcagacgcgcctctgcatctgcgccaggcgaacgggtcctgcgcctcctgcagtcccagctctccaccgccgcgt gcgcctgcagacgctccgctcgctgccttctctcctggcaggcgctgccttttctccccgttaaagggcacttgggctga aggatcgctttgagatctgaggaacccgcagcgctttgagggacctgaagctgtttttcttcgttttcctttgggttcag tttgaacgggaggtttttgatccctttttttcagaatggattatttgctcatgattttctctctgctgtttgtggcttgc caaggagctccagaaacaggtaggcacgctcgttgacttgtaagtctcggaattacaagttagtgtgttcttatccacct tcatgcttttcttgcttctatttttccccgttctttttatgactgcagcttagagagcaagtgtctgagaattattgctg aaacgtactttaagtcttctagtgtaaaatgtaaaattcctctactgaatacaattaggtgcaattgactataacatgac attaaaataacttatcgttttattattattattccattatgtgtttccttggcttttaaaaaatgagaagagtatggaca tatacaatttagtcaaatgtatgtttgtaatatatgtgtttatacaggtacacaggccatataggaacttaaatcttatt taaacactattttaatagtgtgttaacgtgtaaaatatttaagcattccagcttgaagccaaggaattgtatccagtcgt tcaagcaatgtatgttcagtaaaatcacctgcagagcaaaagtctgttgactaactaccgcctcccccgcccccccacca ccccccgcaggcggtttctgggtgaagcagatgttttctttaaaatttgtcatcattgactttaggtttcttttggcagg tttttggcacccaaaacagtgtgagctctcttttcagctttattcacctgtgctgggaggggagctaggataattcttgg ctgccgaaggatttaggcagtgcgtgtgcatctgcccgggtcccccccgtttttagggtcagtgcactttttttgtcttt tcgtgaccctgactaaagagaaaggatgtcaagggaatgaaaatcctggaatgtgtctgatcatttgaaatgtacaaaat tgggcagataagctgcatggctaaattgttaggaggaagaggcaaggcagtagtggagaagggggaggcagtggatccca cacaagcctgatgcccagggattcggaattcaaaatccccccagcctaccttcagtcccctgacctgcttctcagcccca ccttaggtcactggtttctatggagttaccctactgaattgaatattgaatagttaatttctctctccaatcattttccc cacctaattttgaaagatatacatcatctggggtaccctgtgccctacacagcatgtgaagtggatgggtaccccctaaa gagagggtcatcctgaatggggaagtggccccaaagctaggaataactgtgatttcttgtctttagtcatgtgccaatgt taagtaagcttcagtggatagtgctgtcctaccaagttccttgtagaagccagccggattttcaacaggcagcattccac agcatttccctgagcctgcttcaagaggggtgggggaagtcccttttcaggtgtttatctcctctgcatttgtgtaatct ccctgaaggtggataagccaagggcatgagggggaggcaaaaggtgaactcatgttaaggagggaaaaaaataaagagcc cttttttctgtgtttcttgctgatggcaggctgtgtgcttcatctgcttttatctgctctgctagctctgactctactgt gatccagcatgtctctcggcgtttgaggagacatcccccactgacctgctctttctctccccagcagtcttaggcgctga gctcagcgcggtgggtgagaacggcggggagaaacccactcccagtccaccctggcggctccgccggtccaagcgctgct cctgctcgtccctgatggataaagagtgtgtctacttctgccacctggacatcatttgggtcaacactcccgagtaagtc tctagagggcattgtaaccctattcattcattagcgctggctccactggagcccagttttagagtttcttttctagggac tctgaaggtagtccttctaacaccatccaagtgcctcagtggggacagtttccctctattcctgaaaataacgacagctt cgttcttagcaaccaaggggagggtcttctgaggccccgtagctcaggctactcatgatgggacaagcaggaggccactg cacgtttcaaatgaggaactttcagtgagagggcctcagggggacactctcacagtggcatctgatggggtttcgggaat aattgccgaggtcagatgtgggttagtgcaacctgtgcttctcatgggagggtggagactgagaggcagaagtgatgata tagagggttagaatcacttaattttagttacagaaaaacctaggctcaaagtgttgaagccatttgtgcaggagtgagtt tgtagcagagctagaactggagcccggatttcctttgctgctatattttccctttagaaatgcccatttcagaactgaaa tagaaatactgtccataggcttctctttcacctacagagaagaaaagcagatttcctccttctgccctggacactagttc atca ctgtcggaagcagtcataaacaagcacacatttactatgcatacaatgtaccgttatgacaaaggaggaccaaaa tccaaacaatatcaaaccacaccaaaaaccacaaggagcctaataattactaaggtgatacttccaaagggaggacttta tttcttagatgagaatgaaaatggacacattggaaattattggagagccctctggctatgagtccttccacaaccatatg gtaccaccgactggcaggagaaatgtgtgaacatgtgcctcctctccccaaccactggggccggtggggtgacggtggca cttttagcagtatcctccgtggtttgagttgaaaataagttttaaaaatcctgtgagtcatggttttgcattgaaacctc ttcccactgtgtacccacaaatagttaactaaatagaccattagaaaaggaagaaaa ataaagcagatgccaagcagag atgtcctaatttttgacaaaaaagcaatgttgcttgtgtcaagaagaaactgaactttgtgaagagttgaaatggaattc cactgaattagaaaaacttgttttctcctgcctggatacatacagtcagggccattgatgcacaggtgttcctggctgtt gttacactttaccctctgaaatgatgctcccaagtgctatgtgatgagctccttgtgtgcccagtggaataggtgtgtcc atgtgtcattttaaagactattaattacactaatatagtttctttctctctttggataataggcacgttgttccgtatgg acttggaagccctaggtccaagagagccttggagaatttacttcccacaaaggcaacagaccgtgagaatagatgccaat gtgctagccaaaaagacaagaagtgctggaatttttgccaagcaggaaaagaactcaggtgagcagaaacacctttgctt ttcaatcagtttaacagcctcctgaactccttcctatcatggtactgccttcctgttttagagagactaacagagacatt gaaagtcagggtaaagctgaatataacattgctgaaatgtttttccttgtgtattttaacagggctgaagacattatgga gaaagactggaataatcataagaaaggaaaagactgttccaagcttgggaaaaagtgtatttatcagcagttagtgagag gaagaaaaatcagaagaagttcagaggaacacctaagacaaaccaggtaagagggaaggaagaaaaattaggtaagaggt tcacaagaacaactagccccagtcagtgatgccagcagcctgttcctccagcccttcttacccgggcaggtgaaagactt agaaaacagtagcagaggagatctatgcatcctatagattaaaaggagcaaaagaatccctcttaaa atttccatgaag ctctggaatgcaaaccgatgtcctctgtacctttagcacataccatttcatctacaggtagatttcccaaccaaaatata tccagagatgcctttgtcattgggttatatacagcctttgcctctctgagtcaatgtatttaccactttccctgagaaat cgaaaatcattttggggagcggacatttagaaaaagaatcaaagtgtcatggataatcaaattcttcaataagttgcagt tattcagatggccaaaggaaaaataaagtcattagatagggttggtagaatttagaacatgctgtttttcaggtttatgg tctttttttttttttttttttttttttaaatagggaaatgtgtttggtgcagagccaatgtcattccaaaaagctctctc ttttcctggtcagtcatgtgctgggacagagaagggatctggattaggcaacatcatagagttgctctgagctgctcttt ggtgataacccttccaaatcctaaactttttggaattcacaagctcaaaggaggaaacctactctctgatctaccacatg ttctgcatttttcta catggtctatggaaacttctcttagaaatccagtggcaagaagttctatgattaaagtgttctg agctcaggccaggcagtcatgaactacttctgagttgtttactactgatttgtggggcagcctcagctatcggtttcttc acacctgcttatgagagtatccatatttatggtcgcaggcagtaatgctccccacgagatcagtttctgaactaacctgg aattttttatgggtttttattatgccaactattaaatcaacattacagttcttccctctgtatttctcctgtaaaacatt aggcctgcaaaaaaaaaaaatctttttaaaaataattgccataaagtatttgctctgggcctactgtatgcttcttttyt ttttctctcttttcaactaagtcaccgtcaatttattaagatggccataactattcaaaacctatgctgagttcctcaag gcagggtcgcatagtgatgaaggttgggatggggctacggaagaaaccagaacaactctagtttatttaaaacctgtatt tactgcccacttccccttagacttgaccatatgaccccttgctccccattctaagcataggggcaggctttatttttaca atggtaatagatgatatcacttgaggttttatcaaagagttgcggcgggtggtgaaagttcacaaccagattcaggtttt gtttgtgccagattctaattttacatgtttcttttgccaaagggtgatttttttaaaataacatttgttttctcttatct tgctttattaggtcggagaccatgagaaacagcgtcaaatcatcttttcatgatcccaagctgaaaggcaagccctccag agagcgttatgtgacccacaaccgagcacattggtgacagaccttcggggcctgtctgaagccatagcctccacggagag ccctgtggccgactctgcactctccaccctggctgggatcagagcaggagcatcctctgctggttcctgactggcaaagg accagcgtcctcgttcaaaacattccaagaaaggttaaggagttcccccaaccatcttcactggcttccatcagtggtaa ctgctttggtctcttctttcatctggggatgacaatggacctctcagcagaaacacacagtcacattcgaattcgggtgg catcctccggagagagagagaggaaggagattccacacaggggtggagtttctgacgaaggtcctaagggagtgtttgtg tctgactcaggcgcctggcacatttcagggagaaactccaaagtccacacaaagattttctaaggaatgcacaaattgaa aacacactcaaaagacaaacatgcaagtaaagaaaaaaaaaagaaagacttttgtttaaatttgtaaaatgcaaaactga atgaaactgttactaccataaatcaggatatgtttcatgaatatgagtctacctcacctatattgcactctggcagaagt atttcccacatttaattattgcctccccaaactcttcccacccctgctgccccttcctccatcccccatactaaatccta gcctcgtagaagtctggtctaatgtgtcagcagtagatataatattttcatggtaatctactagctctgatccataagaa aaaaaagatcattaaatcaggagattccctgtccttgatttttggagacacaatggtatagggttgtttatgaaatatat tgaaaagtaagtgtttgttacgctttaaagcagtaaaattattttccttta ataaccggctaatgaaagaggttggatt gaattttgatgtacttatttttttatagatatttatattcaaacaatttattccttatatttaccatgttaaatatctgt ttgggcaggccatattggtctatgtatttttaaaatatgtatttctaaatgaaattgagaacatgctttgttttgcctgt caaggtaatgactttagaaaataaatatttttttccttactgtactgatttggaatcattactgaaatttgtaaggagtg ggccaacgtgattaagtaccataaaggcaaataaatggttaaagacggtttcatagaaaagtgacaattagaaggatatt acggtctaagctaattatataaagaattttatctgtatcttaaatgttgattttatactgcattgaggtaaaaacacaaa acaaaaaagcagctttaacacctctgtcttctcttgggtagcagcctcctgcttctccttcacctgaaaaattctccagg gacttcatccattaacttggctcaggctattggcaggattcacagtttaagctgatggtgtggtgagagatgctttatcc atattaatggactgaaggaagtaatggcaagacaaccccccaaaacatacctaattatacaaagttatataccaaagttg cttttagaaaatggcctgctcagagcaagtagaggtttccaatggctttttattttctcacattaaggatgttgtttctt aaggaacattgagtaccattgcttcttcgtgatagcctaggactgccgtgtgcccatggaggtagagacaccaggtactg attctaggtcctctgccacaaagcaccacttcctctccactttgccttggctggccttgtcagctcactggagagcacag tattgcaattgcagtattgcaaatggtcactactaactgaattctctaagagcttgattagccctcgagaatcttccttg cccttctctaatagtgtctgaaggaattcctggcatttaacaaatattagcatgtagtgatcactgtcgtcctaacagtg acacatcagaaggatttcaaataacagtcttcaggcatgcgtaatcaatgtcctgtgcagagtctccgtcctcattgatc ctcatttttctctttaaggcacagtccaatgtctttggggaattgtttataaagcttactttatccataaactgtttctc agtgcgtgactctgaagaaaattttgaagttttgcccatgttgacaaggtgcttggtctgaacttggccagtatttaatc ttgagcaaacgattcaatttccttctatcgtgagttttctcatctatgaaacaagggagttgaggggagtttctttcata cctctgagaaagagtttgagattacataaagaagttgaagtggcatgaaaaaaaataaagatctgagcttagaagacatg gatctaatacatttaagaggaagtcagaatcagagaagccactgaacaaaacagtccaaacggagcatagtaagtcagat tgatgagttttggttgggtttttcatcagtcaaacccttgagcccccctttcccatgcttcctgcttcag atccagtag gaaaaatgaaagggatgatgtagacactctagggcatgaggatttgcagtaaataagttgggagactcacagaaaattaa tatttttcaaacatgaagacgaaacattcaattatattacagtccacatcagcttgaagggtaaactgatgggatgatct gtcacatttcttgctctgtttccagtaaaagcatggtttctggaaacccacttaggacagctttctctctttacactgat agcccaggcaagctttgatctcagaactccagaaaccagagaactctaggtggaatgtggtaacttttgccagggcagag ggaacacctactaataggtacttcatttgcaccaccagagattggcatcttttttgatggatccactggctttgatactg cctgtactcccccaaaacacagcttgggtattggactaatctagagctccctcaggagaactcttgctgacattaagaaa gagcaacattttgtctttccaggtgaaaatccaaggccaaaaagggagtgactcacctaagatcacagaaggagctgtag catctctggagcctgaacacttaagttaagcacgactatttcacgcagagggcatgaattc (SEQ ID NO: 12225) ggagctgtttacccccactctaataggggttcaatataaaaagccggcagagagctgtccaagtcagacgcgcctctgca tctgcgccaggcgaacgggtcctgcgσctcctgcagtcccagctctccaccaccgccgcgtgcgcctgcagacgctccgc tcgctgccttctctcctggcaggcgctgccttttctccccgttaaagggcacttgggctgaaggatcgctttgagatctg aggaacccgcagcgctttgagggacctgaagctgtttttcttcgttttcctttgggttcagtttgaacgggaggtttttg atccctttttttcagaatggattatttgctcatgattttctctctgctgtttgtggcttgccaaggagctccagaaacag cagtcttaggcgctgagctcagcgcggtgggtgagaacggcggggagaaacccactcccagtccaccctggcggctccgc cggtccaagcgctgctcctgctcgtccctgatggataaagagtgtgtctacttctgccacctggacatcatttgggtcaa cactcccgagcacgttgttccgtatggacttggaagccctaggtccaagagagccttggagaatttacttcccacaaagg caacagaccgtgagaatagatgccaatgtgctagccaaaaagacaagaagtgctggaatttttgccaagcaggaaaagaa ctcagggctgaagacattatggagaaagactggaataatcataagaaaggaaaagactgttccaagcttgggaaaaagtg tatttatcagcagttagtgagaggaagaaaaatcagaagaagttcagaggaacacctaagacaaaccaggtcggagacca tgagaaacagcgtcaaatcatcttttcatgatcccaagctgaaaggcaagccctccagagagcgttatgtgacccacaac cgagcacattggtgacagacttcggggcctgtctgaagccatagcctccacggagagccctgtggccgactctgcactct ccaccctggctgggatcagagcaggagcatcctctgctggttcctgactggcaaaggaccagcgtcctcgttcaaaacat tccaagaaaggttaaggagttcccccaaccatcttcactggcttccatcagtggtaactgctttggtctcttctttcatc tggggatgacaatggacctctcagcagaaacacacagtcacattcgaattc (SEQ ID NO: 12226) ctgcgccaggcgaacgggtcctgcgcctcctgcagtcccagctctccaccgccgcgtgcgcctgcagacgctccgctcgc tgccttctctcctggcaggcgctgccttttctccccgttaaagggcacttgggctgaaggatcgctttgagatctgagga acccgcagcgctttgagggacctgaagctgtttttcttcgttttcctttgggttcagtttgaacgggaggtttttgatcc ctttttttcagaatggattatttgctcatgattttctctctgctgtttgtggcttgccaaggagctccagaaacagcagt cttaggcgctgagctcagcgcggtgggtgagaacggcggggagaaacccactcccagtccaccctggcggctccgccggt ccaagcgctgctcctgctcgtccctgatggataaagagtgtgtctacttctgccacctggacatcatttgggtcaacact cccgagcacgttgttccgtatggacttggaagccctaggtccaagagagccttggagaatttacttcccacaaaggcaac agaccgtgagaatagatgccaatgtgctagccaaaaagacaagaagtgctggaatttttgccaagcaggaaaagaactca gggctgaagacattatggagaaagactggaataatcataagaaaggaaaagactgttccaagcttgggaaaaagtgtatt tatcagcagttagtgagaggaagaaaaatcagaagaagttcagaggaacacctaagacaaaccaggtcggagaccatgag aaacagcgtcaaatcatcttttcatgatcccaagctgaaaggcaagccctccagagagcgttatgtgacccacaaccgag cacattggtgacagacttcggggcctgtctgaagccatagcctccacggagagccctgtggccgactctgcactctccac cctggctgggatcagagcaggagcatcctctgctggttcctgactggcaaaggaccagcgtcctcgttcaaaacattcca agaaaggttaaggagttcccccaaccatcttcactggcttccatcagtggtaactgctttggtctcttctt catctggg gatgacaatggacctctcagcagaaacacacagtcacattcgaattc (SEQ ID NO: 12227) gatatcctattaatacagagatacagaaagaaatacataaaaaatagttttatcaaatactttccagcattcaagtgtag cctcaaaagcaagaataggccaggagtggtggctcacgctgtaatccacagcactgtgggaggccaaggtaagaggattg cttgaggccaggatttcaagaccagcctaggcaacatagtgagatccctatctctacgaaaaaattttaaaacttagctg ggcatggtgcttgagcctgttgtcccagctactcaggaggtgaagtaggagtgtcacttgagcccaggaggttgaggctg cagtgagctataactgcaccactgcactccagccttggagacagagtgagaccctgtccccaaaaaaattaaaattgaga aaaaaaaaaaggcaagaacagccacagcaaactttctattggggaaaaaaaaaaatcctcctctttacatctctcccttc cttcccttccctttctgagagtgactgtggccaaaaggagcattttccccctgcagtcctctgaggggtggggtggggct atgaagctatccttcatattcactcctttgtccagctcttttcacctctagttcttctccccgcatctctgtctagcagt gccttaagtggaggaggggtgggggcatcaagcttgtaaaactggtttgttggggttctccttctcccctcatttcttga ttcttgggaaaatgtcttgctgggaggctgcctggcgagtgccctagctgccttctgtgggcttgaatggggcttccctc tgcccctacaggaggaaaagggagctgctgccagagggagaaatggagagatggacagagaaggcaggtgccacccctcg cccctgacacacaaagaaaaagacacggaaattctctctctctcttctcttctcctatctctctctctctccctctctct ctctctctctctctctctcacacacacacacacacacacacacacacacacaggcgcgcgccgcgcgcgcaggcacacgt cttgcaaattcaggattcaaagagacaggggcaccattatatttggcacggtggggccttccaggtctgaaatcctgcat tcttccttactatttactttccccgagctcgagaagggccaggtgtgggcggatggctggccacgttttgtgtttccaat tcatattcacgggatgacacagacggggcgtggtgagtgctgttggaggcgcttgggcagtttcattttgccccacttct ccacctgaaggctgggcgttgctggaacctgcaggggcagcctcagcaaggtggggtggcgtggagtggggtgggagaag ggactccagctgaagtagaacccaggctggacctgagaatattggggagggcatgggcggtggtttccgggtaggggcct tgaggacatgttggtcctgactgttgtcagtgtttggtcaaagttgccaaaaggttaaaaaaaaaaaagtagggggagtc cctgccaagacatatttcccaggccacctttcttccgcgggagtgttgggggggaggcgctgcttggaacctgtgaatgt gacatcagctctcctctcctctcccaaggtcggctttggagagggaggtcagggcacccttgcctggcacaggcacgctg gcttccggctcagtgccgcctgctctccgggagctgtgcgctccctgggccccggggctaggctgaggtaagcgcacagc ggaggccaggcgcgccggcagaggcctgggggatagggtggaggcatctctgggtgtgggtgtgggtgtgggtgtgggag ggagagttcttgcctctctctctcccatctccaactcttgcttcagtggctcttttagaggatgcatgtcattatggacc tgtcgctgccactgtccctgttcccccagctgtgacttcgagggaggtctggggatctgagtctgtccaaacccacggct ttgctgttgggataaaaactgtccttttgattttagaaggaggagggaaaaaaggtttcccagcatgtgtgttgtgccag tcttggaaattcatccgtgcttgaattccaccctccatccccagaaaaactggagtaaaacaaaaagaggagatggacaa agtgtgtatttgatggcatcccctgggaagagactctaaatttatcccataggtcttactgggccactgtgagcgctttg gtggagaacaaacaaaaattctgggtgctcagttgtctaacctgaaaaatgggactagcggaaaaagccaatgtgttcca tgcaccttttgctttctttattaaggcatgatgtcacctgtacagtaactgccctgtgtgtacttcagggggggatt ca aggttagatagacaggaaattgttttgaaaatgtaaacacattattaaatgtgaagtattatctgattccttgttcgaat ggcatttccttctcagcaccaccttccttgcatattcacttaaccttgtacaagaacacctttttgccctaaatgaagac acccccccaaaaaaaagagtcccagaaaatatgtccctgcttgtgcgggaataaatagaatattctgaggtgcattcctc cttcctatgttaggcaacattccttgaccctcctcggcccccaagccaggttgcgtttttttctgccatttagaagggtt ttcctttttgtcctagtaaaacatcagcccctgtagctcttcatctccccctggtgttcttctcccgccatgtcttaaga ttggtggcaccgaccaatcttaagatttaagttctgtgtgaaaaacacctttgσttttcaatcagtttatcagcctcctc cgcaggggaatgtggacacacaaaagaacttatcggggcttctcatcagtgatagggaaaagactggcatgtgcctaaac gagctctgatgttatttttaagctccctttcttgccaatccctcacggatctttctccgatagatgcaaagaacttcagc aaaaaagacccgcaggaaggggcttgaagagaaaagtacgttgatctgccaaaatagtctgacccccagtagtgggcagt gacgagggagagcattcccttgtttgactgagactagaatcggagagacataaaaggaaaatgaagcgagcaacaattaa aaaaaattccccgcacacaacaatacaatctatttaaactgtggctcatacttttcataccaatggtatgactttttttc tggagtcccctcttctgattcttgaactccggggctggcagcttgcaaaggggaagcggactccagcactgcacgggcag gtttagcaaaggtctctaatgggtattttctttttcttagccctgcccccgaattgtcagacggcgggcgtctgcttctg aagttagcagtgatttcctttcgggcctggcttatctccggctgcacgttgcctgttggtgactaataacacaataacat tgtctggggctggaataaagtcggagctgtttacccccactctaataggggttcaatataaaaagccggcagagagctgt ccaagtcagacgcgcctctgcatctgcgccaggcgaacgggtcctgcgcctcctgcagtcccagctctccaccgccgcgt gcgcctgcagacgctccgctcgctgccttctctcctggcaggcgctgccttttctccccgttaaagggcacttgggctga aggatcgctttgagatctgaggaacccgcagcgctttgagggacctgaagctgtttttcttcgttttcctttgggttcag . tttgaacgggaggtttttgatccctttttttcagaatggattatttgctcatgattttctctctgctgtttgtggcttgc caaggagctccagaaacaggtaggcacgctcgttgacttgtaagtctcggaattacaagttagtgtgttcttatccacct tcatgcttttcttgcttctatttttccccgttctttttatgactgcagcttagagagcaagtgtctgagaattattgctg aaacgtactttaagtcttctagtgtaaaatgtaaaattcctctactgaatacaattaggtgcaattgactataacatgac attaaaataacttatcgttttattattattattccattatgtgtttccttggcttttaaaaaatgagaagagtatggaca tatacaatttagtcaaatgtatgtttgtaatatatgtgtttatacaggtacacaggccatataggaacttaaatcttatt taaacactattttaatagtgtgttaacgtgtaaaatatttaagcattccagcttgaagccaaggaattgtatccagtcgt tcaagcaatgtatgttcagtaaaatcacctgcagagcaaaagtctgttgactaactaccgcctcccccgcccccccacca ccccccgcaggcggtttctgggtgaagcagatgttttctttaaaatttg catcattgactttaggtttcttttggcagg tttttggcacccaaaacagtgtgagctctcttttcagctttattcacctgtgctgggaggggagctaggataattcttgg ctgccgaaggatttaggcagtgcgtgtgcatctgcccgggtcccccccgtttttagggtcagtgcactttttttgtcttt tcgtgaccctgactaaagagaaaggatgtcaagggaatgaaaatcctggaatgtgtctgatcatttgaaatgtacaaaat tgggcagataagctgcatggctaaattgttaggaggaagaggcaaggcagtagtggagaagggggaggcagtggatccca cacaagcctgatgcccagggattcggaattcaaaatccccccagcctaccttcagtcccctgacctgcttctcagcccca ccttaggtcactggtttctatggagttaccctactgaattgaatattgaatagttaatttctctctccaatcattttccc cacctaattttgaaagatataca catctggggtaccctgtgccctacacagcatgtgaagtggatgggtaccccctaaa gagagggtcatcctgaatggggaagtggccccaaagctaggaataactgtgatttcttgtctttagtcatgtgccaatgt taagtaagcttcagtggatagtgctgtcctaccaagttccttgtagaagccagccggattttcaacaggcagcattccac agcatttccctgagcctgcttcaagaggggtgggggaagtcccttttcaggtgtttatctcctctgcatttgtgtaatct ccctgaaggtggataagccaagggcatgagggggaggcaaaaggtgaactcatgttaaggagggaaaaaaataaagagcc cttttttctgtgtttcttgctgatggcaggctgtgtgcttcatctgcttttatctgctctgctagctctgactctactgt gatccagcatgtctctcggcgtttgaggagacatcccccactgacctgctctttctctccccagcagtcttaggcgctga gctcagcgcggtgggtgagaacggcggggagaaacccactcccagtccaccctggcggctccgccggtccaagcgctgct cctgctcgtccctgatggataaagagtgtgtctacttctgccacctggacatcatttgggtcaacactcccgagtaagtc tctagagggcattgtaaccctattcattcattagcgctggctccactggagcccagttttagagtttcttttctagggac tctgaaggtagtccttctaacaccatccaagtgcctcagtggggacagtttccctctattcctgaaaataacgacagctt cgttcttagcaaccaaggggagggtcttctgaggccccgtagctcaggctactcatgatgggacaagcaggaggccactg cacgtttcaaatgaggaactttcagtgagagggcctcagggggacactctcacagtggcatctgatggggtttcgggaat aattgccgaggtcagatgtgggttagtgcaacctgtgcttctcatgggagggtggagactgagaggcagaagtgatgata tagagggttagaatcacttaattttagttacagaaaaacctaggctcaaagtgttgaagccatttgtgcaggagtgagtt tgtagcagagctagaactggagcccggatttcctttgctgctatattttccctttagaaatgcccatttcagaactgaaa tagaaatactgtccataggcttctctttcacctacagagaagaaaagcagatttcctccttctgccctggacactagttc atcatctgtcggaagcagtcataaacaagcacacatttactatgcatacaatgtaccgttatgacaaaggaggaccaaaa tccaaacaatatcaaaccacaccaaaaaccacaaggagcctaataattactaaggtgatacttccaaagggaggacttta tttcttagatgagaatgaaaatggacacattggaaattattggagagccctctggctatgagtccttccacaaccatatg gtaccaccgactggcaggagaaatgtgtgaacatgtgcctcctctccccaaccactggggccggtggggtgacggtggca cttttagcagtatcctccgtggtttgagttgaaaataagttttaaaaatcctgtgagtcatggttttgcattgaaacctc ttcccactgtgtacccacaaatagttaactaaatagaccattagaaaaggaagaaaatataaagcagatgccaagcagag atgtcctaatttttgacaaaaaagcaatgttgcttgtgtcaagaagaaactgaactttgtgaagagttgaaatggaattc cactgaattagaaaaacttgttttctcctgcctggatacatacagtcagggccattgatgcacaggtgttcctggctgtt gttacactttaccctctgaaatgatgctcccaagtgctatgtgatgagctccttgtgtgcccagtggaataggtgtgtcc atgtgtcattttaaagactattaattacactaatatagtttctttctctctttggataataggcacgttgttccgtatgg acttggaagccctaggtccaagagagccttggagaatttacttcccacaaaggcaacagaccgtgagaatagatgccaat gtgctagccaaaaagacaagaagtgctggaatttttgccaagcaggaaaagaactcaggtgagcagaaacacctttgctt ttcaatcagtttaacagcctcctgaactccttcctatcatggtactgccttcctgttttagagagactaacagagacatt gaaagtcagggtaaagctgaatataacattgctgaaatgtttttccttgtgtattttaacagggctgaagacattatgga gaaagactggaataatcataagaaaggaaaagactgttccaagcttgggaaaaagtgtatttatcagcagttagtgagag gaagaaaaatcagaagaagttcagaggaacacctaagacaaaccaggtaagagggaaggaagaaaaattaggtaagaggt tcacaagaacaactagccccagtcagtgatgccagcagcctgttcctccagcccttcttacccgggcaggtgaaagactt agaaaacagtagcagaggagatctatgcatcctatagattaaaaggagcaaaagaatccctcttaaatatttccatgaag ctctggaatgcaaaccgatgtcctctgtacctttagcacataccatttcatctacaggtagatttcccaaccaaaatata tccagagatgcctttgtcattgggtta atacagcctttgcctctctgagtcaatgtatttaccactttccctgagaaat cgaaaatcattttggggagcggacatttagaaaaagaatcaaagtgtcatggataatcaaattcttcaataagttgcagt tattcagatggccaaaggaaaaataaagtcattagatagggttggtagaatttagaacatgctgtttttcaggtttatgg tctttttttttttttttttttttttttaaatagggaaatgtgtttggtgcagagccaatgtcattccaaaaagctctctc ttttcctggtcagtcatgtgctgggacagagaagggatctggattaggcaacatcatagagttgctctgagctgctcttt ggtgataacccttccaaatccta^'aactttttggaattcacaagctcaaaggaggaaacctactctctgatctaccacatg ttctgcatttttctatcatggtctatggaaacttctcttagaaatccagtggcaagaagttctatgattaaagtgttctg agctcaggccaggcagtcatgaactacttctgagttgtttactactgatttgtggggcagcctcagc atcggtttcttc acacctgcttatgagagtatccatatttatggtcgcaggcagtaatgctccccacgagatcagtttctgaactaacctgg aattttttatgggtttttattatgccaactattaaatcaacattacagttcttccctctgtatttctcctgtaaaacatt aggcctgcaaaaaaaaaaaatctttttaaaaataattgccataaagtatttgctctgggcctactgtatgcttcttttyt ttttctctcttttcaactaagtcaccgtcaatttattaagatggccataactattcaaaacctatgctgagttcctcaag gcagggtcgcatagtgatgaaggttgggatggggctacggaagaaaccagaacaactctagtttatttaaaacctgtatt tactgcccacttccccttagacttgaccatatgaccccttgctccccattctaagcataggggcaggctttatttttaca atggtaatagatgatatcacttgaggttttatcaaagagttgcggcgggtggtgaaagttcacaaccagattcaggtttt gtttgtgccagattctaattttacatgtttcttttgccaaagggtgatttttttaaaataacatttgttttctcttatct tgctttattaggtcggagaccatgagaaacagcgtcaaatcatcttttcatgatcccaagctgaaaggcaagccctccag agagcgttatgtgacccacaaccgagcacattggtgacagaccttcggggcctgtctgaagccatagcctccacggagag ccctgtggccgactctgcactctccaccctggctgggatcagagcaggagcatcctctgctggttcctgactggcaaagg accagcgtcctcgttcaaaacattccaagaaaggttaaggagttcccccaaccatcttcactggcttccatcagtggtaa ctgctttggtctcttctttcatctggggatgacaatggacctctcagcagaaacacacagtcacattcgaattcgggtgg catcctccggagagagagagaggaaggagattccacacaggggtggagtttctgacgaaggtcctaagggagtgtttgtg tctgactcaggcgcctggcacatttcagggagaaactccaaagtccacacaaagattttctaaggaatgcacaaattgaa aacacactcaaaagacaaacatgcaagtaaagaaaaaaaaaagaaagacttttgtttaaatttgtaaaatgcaaaactga atgaaactgttactaccataaatcaggatatgtttcatgaatatgagtctacctcacctatattgcactctggcagaagt atttcccacatttaattattgcctccccaaactcttcccacccctgctgccccttcctccatcccccatactaaatccta gcctcgtagaagtctggtctaatgtgtcagcagtagatataatattttcatggtaatctactagctctgatccataagaa aaaaaagatcattaaatcaggagattccctgtccttgatttttggagacacaatggtatagggttgtttatgaaatat t tgaaaagtaagtgtttgttacgctttaaagcagtaaaattattttcctttatataaccggctaatgaaagaggttggatt gaattttgatgtacttatttttttatagatatttatattcaaacaatttattccttatatttaccatgttaaatatctgt ttgggcaggccatattggtctatgtatttttaaaatatgtatttctaaatgaaattgagaacatgctttgttttgcctgt caaggtaatgactttagaaaataaatatttttttccttactgtactgatttggaatcattactgaaatttgtaaggagtg ggccaacgtgattaagtaccataaaggcaaataaatggttaaagacggtttcatagaaaagtgacaattagaaggatatt acggtctaagctaattatataaagaattttatctgta cttaaatgttgattttatactgcattgaggtaaaaacacaaa acaaaaaagcagctttaacacctctgtcttctcttgggtagcagcctcctgcttctccttcacctgaaaaattctccagg gacttcatccattaacttggctcaggctattggcaggattcacagtttaagctgatggtgtggtgagagatgctttatcc atattaatggactgaaggaagtaatggcaagacaaccccccaaaacatacctaattatacaaagttatataccaaagttg cttttagaaaatggcctgctcagagcaagtagaggtttccaatggctttttattttctcacattaaggatgttgtttctt aaggaacattgagtaccattgcttcttcgtgatagcctaggactgccgtgtgcccatggaggtagagacaccaggtactg attctaggtcctctgccacaaagcaccacttcctctccactttgccttggctggccttgtcagctcactggagagcacag tattgcaattgcagtattgcaaatggtcactactaactgaattctctaagagcttgattagccctcgagaatcttccttg cccttctctaatagtgtctgaaggaattcctggcatttaacaaatattagcatgtagtgatcactgtcgtcctaacagtg acacatcagaaggatttcaaataacagtcttcaggcatgcgtaatcaatgtcctgtgcagagtctccgtcc cattgatc ctcatttttctctttaaggcacagtccaatgtctttggggaattgtttataaagcttactttatccataaactgtttctc agtgcgtgactctgaagaaaattttgaagttttgcccatgttgacaaggtgcttggtctgaacttggccagtatttaatc ttgagcaaacgattcaatttccttctatcgtgagttttctcatctatgaaacaagggagttgaggggagtttctttcata cctctgagaaagagtttgagattacataaagaagttgaagtggcatgaaaaaaaataaagatctgagcttagaagacatg gatctaatacatttaagaggaagtcagaatcagagaagccactgaacaaaacagtccaaacggagcatagtaagtcagat tgatgagttttggttgggtttttcatcagtcaaacccttgagcccccctttcccatgcttcctgcttcagtatccagtag gaaaaatgaaagggatgatgtagacactctagggcatgaggatttgcagtaaataagttgggagactcacagaaaattaa tatttttcaaacatgaagacgaaacattcaattatattacagtccacatcagcttgaagggtaaactgatgggatgatct gtcacatttcttgctctgtttccagtaaaagcatggtttctggaaacccacttaggacagctttctctctttacactgat agcccaggcaagctttgatctcagaactccagaaaccagagaactctaggtggaatgtggtaacttttgccagggcagag ggaacacctactaataggtacttcatttgcaccaccagagattggcatcttttttgatggatccactggctttgatactg cctgtactcccccaaaacacagcttgggtattggactaatctagagctccctcaggagaactcttgctgacattaagaaa gagcaacattttgtctttccaggtgaaaatccaaggccaaaaagggagtgactcacctaagatcacagaaggagctgtag catctctggagcctgaacacttaagttaagcacgactatttcacgcagagggcatgaattcggagctgtttacccccact ctaataggggttcaatataaaaagccggcagagagctgtccaagtcagacgcgcctctgcatctgcgccaggcgaacggg tcctgcgcctcctgcagtcccagctctccaccaccgccgcgtgcgcctgcagacgctccgctcgctgccttctctcctgg caggcgctgccttttctccccgttaaagggcacttgggctgaaggatcgctttgagatctgaggaacccgcagcgctttg agggacctgaagctgtttttcttcgttttcctttgggttcagtttgaacgggaggtttttgatccctttttttcagaatg gattatttgctcatgattttctctctgctgtttgtggcttgccaaggagctccagaaacagcagtcttaggcgctgagct cagcgcggtgggtgagaacggcggggagaaacccactcccagtccaccctggcggctccgccggtccaagcgctgctcct gctcgtccctgatggataaagagtgtgtctacttctgccacctggacatcatttgggtcaacactcccgagcacgttgtt ccgtatggacttggaagccctaggtccaagagagccttggagaatttacttcccacaaaggcaacagaccgtgagaatag atgccaatgtgctagccaaaaagacaagaagtgctggaatttttgccaagcaggaaaagaactcagggctgaagacatta tggagaaagactggaataatcataagaaaggaaaagactgttccaagcttgggaaaaagtgtatttatcagcagttagtg agaggaagaaaaatcagaagaagttcagaggaacacctaagacaaaccaggtcggagaccatgagaaacagcgtcaaatc a cttttcatgatcccaagctgaaaggcaagccctccagagagcgttatgtgacccacaaccgagcacattggtgacaga cttcggggcctgtctgaagccatagcctccacggagagccctgtggccgactctgcactctccaccctggctgggatcag agcaggagcatcctctgctggttcctgactggcaaaggaccagcgtcctcgttcaaaacattccaagaaaggttaaggag ttcccccaaccatcttcactggcttccatcagtggtaactgctttggtctcttctttcatctggggatgacaatggacct ctcagcagaaacacacagtcacattcgaattcctgcgccaggcgaacgggtcctgcgcctcctgcagtcccagctctcca ccgccgcgtgcgcctgcagacgctccgctcgctgccttctctcctggcaggcgctgccttttctccccgttaaagggcac ttgggctgaaggatcgctttgagatctgaggaacccgcagcgctttgagggacctgaagctgtttttcttcgttttcctt tgggttcagtttgaacgggaggtttttgatccctttttttcagaatggattatttgctcatgattttctctctgctgttt gtggcttgccaaggagctccagaaacagcagtcttaggcgctgagctcagcgcggtgggtgagaacggcggggagaaacc cactcccagtccaccctggcggctccgccggtccaagcgctgctcctgctcgtccctgatggataaagagtgtgtctact tctgccacctggacatcatttgggtcaacactcccgagcacgttgttccgtatggacttggaagccctaggtccaagaga gccttggagaatttacttcccacaaaggcaacagaccgtgagaatagatgccaatgtgctagccaaaaagacaagaagtg ctggaatttttgccaagcaggaaaagaactcagggctgaagacattatggagaaagactggaataatcataagaaaggaa aagactgttccaagcttgggaaaaagtgtatttatcagcagttagtgagaggaagaaaaatcagaagaagttcagaggaa cacctaagacaaaccaggtcggagaccatgagaaacagcgtcaaatcatcttttcatgatcccaagctgaaaggcaagcc ctccagagagcgttatgtgacccacaaccgagcacattggtgacagacttcggggcctgtctgaagccatagcctccacg gagagccctgtggccgactctgcactctccaccctggctgggatcagagcaggagcatcctctgctggttcctgactggc aaaggaccagcgtcctcgttcaaaacattccaagaaaggttaaggagttcccccaaccatcttcactggcttccatcagt ggtaactgctttggtctcttctttcatctggggatgacaatggacctctcagcagaaacacacagtcacattcgaattc (SEQ ID NO: 12228) aggggcagctggatcagttctcacaggagccacagctcagagactgggaaacatggttccaaaactgttcacttcccaaa tttgtctgcttcttctgttggggcttatgggtgtggagggctcactccatgccagacccccacagtttacgagggctcag tggtttgccatccagcacatcagtctgaacccccctcgatgcaccattgcaatgcgggcaattaacaattatcgatggcg ttgcaaaaaccaaaatacttttcttcgtacaacttttgctaatgtagttaatgtttgtggtaaccaaagtatacgctgcc ctcataacagaactctcaacaattgtcatcggagtagattccgggtgcctttactccactgtgacctcataaatccaggt gcacagaatatttcaaactgcaggtatgcagacagaccaggaaggaggttctatgtagttgcatgtgacaacagagatcc acgggattctccacggtatcctgtggttccagttcacctggataccaccatctaagctcctgtatcagcagtcctcatca tcactcatctgccaagctcctcaatcatagccaagatcccatccctccatgtactctgggtatcagcaactgtcctcatc agtctccataccccttcagctttcctgagctgaagtcccttgtgaaccctgcaataaactgctttgcaaattcaaaaa (SEQ ID NO: 12229) gaacaaccagctggatcagttctcacaggagccacagctcagagactgggaaacatggttccaaaactgttcacttccca aatttgtctgcttcttctgttggggcttatgggtgtggagggctcactccatgccagacccccacagtttacgagggctc agtggtttgccatccagcacatcagtctgaacccccctcgatgcaccattgcaatgcgggcaattaacaattatcgatgg cgttgcaaaaaccaaaatacttttcttcgtacaacttttgctaatgtagttaatgtttgtggtaaccaaagtatacgctg ccctcataacagaactctcaacaattgtcatcggagtagattccgggtgcctttactccactgtgacctcataaatccag gtgcacagaatatttcaaactgcaggtatgcagacagaccaggaaggaggttctatgtagttgcatgtgacaacagagat ccacgggattctccacggtatcctgtggttccagttcacctggataccaccatctaagctcctgtatcagcagtcctcat catcactcatctgccaagctcctcaatcatagccaagatcccatccctccatgtactctggg a cagcaactgtcctca tcagtctccataccccttcagctttcctgagctgaagtcccttgtgaaccctgcaataaactgctttgcaaattc (SEQ ID Nθ:122₃0) ctgccagcagcgtatagttttcacccagagtccagatcccaccggcaaaactctgtctaacacaggatgacttggaatta gagtccgtatagcagaaagagcagcagggctgtccttgggtatccgttgctcagccaagtcatcaaataaaaaggatgat tgcacaagtggaccatgtgtcaatctgtgggtttctgcatggccagacccaccaagggaagctttatttaaacagttcca agtaggggagaccagctgcccctgaaccccagaacaaccagctggatcagttctcacaggagccacagctcagagactgg gtaagtcaacaatccccagagctgggacaggaggggcagcgacagggcagcacctgagggagaggtgagctgaagttagt gcttaggagatgtggcacactttggggacaggaagaaaaggaaatgcgaccccagagtggcagcagaggggcctgtgggt tgagacactatagagtgtgtcataaccgagaccggataggggagtagttacttctcttcttttcttacaggaaacatggt tccaaaactgttcacttcccaaatttgtctgcttcttctgttggggcttatgggtgtggagggctcactccatgccagac ccccacagtttacgagggctcagtggtttgccatccagcacatcagtctgaacccccctcgatgcaccattgcaatgcgg gcaattaacaattatcgatggcgttgcaaaaaccaaaatacttttcttcgtacaacttttgctaatgtagttaatgtttg tggtaaccaaagtatacgctgccctcataacagaactctcaacaattgtcatcggagtagattccgggtgcctt actcc actgtgacctcataaatccaggtgcacagaatatttcaaactgcaggtatgcagacagaccaggaaggaggttctatgta gttgcatgtgacaacagagatccacgggattctccacggtatcctgtggttccagttcacctggataccaccatctaagc tcctgtatcagcagtcctca catcactcatctgccaagctcctcaatcatagccaagatcccatccctccatgtactct gggtatcagcaactgtcctcatcagtctccataccccttcagctttcctgagctgaagtcccttgtgaaccctgcaataa actgctttgcaaattcatctggaagtgtctgtgtgtcttcctcggccgctctgctgtcatttagtgacaatctgctctag agatttgggtttatcatgaatctctccccctcaatatctgaccaaattccttgattcccccatcatccttcatgtgatac ctgattccaggcctgccttaaaaaaaaatccaattgagtcaacttagcattggtctccctagccttaatatctcctctaa gcaattttccat (SEQ ID NO:12231) aggggcagctggatcagttctcacaggagccacagctcagagactgggaaacatggttccaaaactgttcacttcccaaa tttgtctgcttcttctgttggggcttatgggtgtggagggctcactccatgccagacccccacagtttacgagggctcag tggtttgccatccagcacatcagtctgaacccccctcgatgcaccattgcaatgcgggcaattaacaattatcgatggcg ttgcaaaaaccaaaatacttttcttcgtacaacttttgctaatgtagttaatgtttgtggtaaccaaagtatacgctgcc ctcataacagaactctcaacaattgtcatcggagtagattccgggtgcctttactccactgtgacctcataaatccaggt gcacagaatatttcaaactgcaggtatgcagacagaccaggaaggaggttctatgtagttgcatgtgacaacagagatcc acgggattctccacggtatcctgtggttccagttcacctggataccaccatctaagctcctgtatcagcagtcctcatca tcactcatctgccaagctcctcaatcatagccaagatcccatccctccatgtactctggg atcagcaactgtcctcatc agtctccataccccttcagctttcctgagctgaagtcccttgtgaaccctgcaataaactgctttgcaaattcaaaaaga acaaccagctggatcagttctcacaggagccacagctcagagactgggaaacatggttccaaaactgttcacttcccaaa tttgtctgcttcttctgttggggcttatgggtgtggagggctcactccatgccagacccccacagtttacgagggctcag tggtttgccatccagcacatcagtctgaacccccctcgatgcaccattgcaatgcgggcaattaacaattatcgatggcg ttgcaaaaaccaaaatacttttcttcgtacaacttttgctaatgtagttaatgtttgtggtaaccaaagtatacgctgcc ctcataacagaactctcaacaattgtcatcggagtagattccgggtgcctttac ccactgtgacctcataaatccaggt gcacagaatatttcaaactgcaggtatgcagacagaccaggaaggaggttctatgtagttgcatgtgacaacagagatcc acgggattctccacggtatcctgtggttccagttcacctggataccaccatctaagctcctgtatcagcagtcctcatca tcactcatctgccaagctcctcaatcatagccaagatcccatccctccatgtactctgggtatcagcaactgtcctcatc agtctccataccccttcagctttcctgagctgaagtcccttgtgaaccctgcaataaactgctttgcaaattcctgccag cagcgtatagttttcacccagagtccagatcccaccggcaaaactctgtctaacacaggatgacttggaattagagtccg tatagcagaaagagcagcagggctgtccttgggtatccgttgctcagccaagtcatcaaataaaaaggatgattgcacaa gtggaccatgtgtcaatctgtgggtttctgcatggccagacccaccaagggaagctttatttaaacagttccaagtaggg gagaccagctgcccctgaaccccagaacaaccagctggatcagttctcacaggagccacagctcagagactgggtaagtc aacaatccccagagctgggacaggaggggcagcgacagggcagcacctgagggagaggtgagctgaagttagtgcttagg agatgtggcacactttggggacaggaagaaaaggaaatgcgaccccagagtggcagcagaggggcctgtgggttgagaca ctatagagtgtgtcataaccgagaccggataggggagtagttacttctcttcttttcttacaggaaacatggttccaaaa ctgttcacttcccaaatttgtctgcttcttctgttggggcttatgggtgtggagggctcactccatgccagacccccaca gtttacgagggctcagtggtttgccatccagcacatcagtctgaacccccctcgatgcaccattgcaatgcgggcaatta acaattatcgatggcgttgcaaaaaccaaaa acttttcttcgtacaacttttgctaatgtagttaatgtttgtggtaac caaagtatacgctgccctcataacagaactctcaacaattgtcatcggagtagattccgggtgcctttactccactgtga cctcataaatccaggtgcacagaatatttcaaactgcaggtatgcagacagaccaggaaggaggttctatgtagttgcat gtgacaacagagatccacgggattctccacggtatcctgtggttccagttcacctggataccaccatctaagctcctgta tcagcagtcctcatcatcactcatctgccaagctcctcaatcatagccaagatcccatccctccatgtactctgggtatc agcaactgtcctcatcagtctccataccccttcagctttcctgagctgaagtcccttgtgaaccctgcaataaactgctt tgcaaattcatctggaagtgtctgtgtgtcttcctcggccgctctgctgtcatttagtgacaatctgctctagagatttg ggtttatcatgaatctctccccctcaatatctgaccaaattccttgattcccccatcatccttcatgtgatacctgattc caggcctgccttaaaaaaaaatccaattgagtcaacttagcattggtctccctagccttaatatctcctctaagcaattt tccat (SEQ ID Nθ:12232) cacaggagctacagcgcggagactggaaacatggttccaaaactgttcacttcccaaatttgtctgcttcttctgttggg gcttctggctgtggagggctcactccatgtcaaacctccacagtttacctgggctcaatggtttgaaacccagcacatca atatgacctcccagcaatgcaccaatgcaatgcaggtca aacaattatcaacggcgatgcaaaaaccaaaatactttc cttcttacaacttttgctaacgtagttaatgtttgtggtaacccaaatatgacctgtcctagtaacaaaactcgcaaaaa ttgtcaccacagtggaagccaggtgcctttaatccactgtaacctcacaactccaagtccacagaatatttcaaactgca ggtatgcgcagacaccagcaaacatgttctatatagttgcatgtgacaacagagatcaacgacgagaccctccacagtat ccggtggttccagttcacctggatagaatcatctaagctcctgtatcagcactcc catcat actcatctgccaagctc ctcaatcatagccaagatcccatctctccatatactttgggtatcagcatctgtcctcatcagtctccataccccttcag ctttcctgagctgaagtgccttgtgaaccctgcaataaactgctttgcaaattc (SEQ ID NO: 12233) ctgcaggcagcatatagttttcatccagagtttggatctaaccagcaaaactctgtcttacacaggatgacttggaatta gagtccttatagcagaaagagcagcagggctgtccttgggtatccgttgctcagccaagtcatcaaataaaaaggatgat tgcacaagtggactatgtaccaatctgtgggtttctgcatggccaagagccagaccctccctctgggctctgctggccca acccaccaagggatgctttatttaaacagttccaagtaggggagaccagctgcccctgaaccccagaacaaccagctgga tcagttctcacaggagctacagcgcggagactgggtaagtcaacgatccccagagctgggacagaaggggcagcaatggg gcagcaactgagggagaagagagctgacgttagtgcttaggagacgttgcacactttgcagacaggaagtaaaggaaatg ggaccccagagtggccgcagaggggcctgtggggtaagacactacagtgtgtgtcataaccaagacccgatcagggagta gt acttctcttcttttcttacaggaaacatggttccaaaactgttcacttcccaaatttgtctgcttcttctgttgggg cttctggctgtggagggctcactccatgtcaaacctccacagtttacctgggctcaatggtttgaaacccagcacatcaa tatgacctcccagcaatgcaccaatgcaatgcaggtcat aacaattatcaacggcgatgcaaaaaccaaaatactt cc ttcttacaacttttgctaacgtagttaatgtttgtggtaacccaaatatgacctgtcctagtaacaaaactcgcaaaaat tgtcaccacagtggaagccaggtgcctttaatccactgtaacctcacaactccaagtccacagaatatttcaaactgcag gtatgcgcagacaccagcaaacatgttctatatagttgcatgtgacaacagagatcaacgacgagaccctccacagtatc cggtggttccagttcacctggatagaatcatctaagctcctgtatcagcactcctcatcatcactcatctgccaagctcc tcaatcatagccaagatcccatctctccatatactttgggtatcagcatctgtcctcatcagtctccataccccttcage tttcctgagctgaagtgccttgtgaaccctgcaataaactgctttgcaaattcatctgaaagtgtctgtgtgtcttcatt agccgctctgctgtcatttagtgacaatctactctagagatttttcttcctctaacctgagacttccgggaaacagagag atttgaagataagagacgctttctgtcatgaaacagcacagtcttatccctctccctgctttaggctgagaagctgaggt ctcaaccgatatctagcaactgtcgaagactcttgctttgatcaagctt (SEQ ID NO: 12234) gctgcccctgaaccccagaacaaccagctggatcagttctcacaggagctacaggccggagactgggaaacatggttcca aaactgttcacttcccaaatttgtctgcttcttctgttggggcttctggctgtggagggctcactccatgtcaaacctcc acagtttacctgggctcaatggtttgaaacccagcacatcaatatgacctcccagcaatgcaccaatgcaatgcaggtca ttaacaattatcaacggcgatgcaaaaaccaaaatactttccttcttacaacttttgctaacgtagttaatgtttgtggt aacccaaatatgacctgtcctagtaacaaaactcgcaaaaattgtcaccacagtggaagccaggtgcctttaatccactg taacctcacaactccaagtccacagaatatttcaaactgcaggtatgcgcagacaccagcaaacatgttctatatagttg catgtgacaacagagatcaacgacgagaccctccacagtatccggtggttccagttcacctggatagaatcatctaagct cctgta cagcactcc catcatcactcatctgccaagctcctcaatcatagccaagatcccatctctccatatactttg ggtatcagcatctgtcctcatcagtctccataccccttcagctttcctgagctgaagtgccttgtgaaccctgcaataaa ctgctttgcaaattc (SEQ ID NO:122₃5) cacaggagctacagcgcggagactggaaacatggttccaaaactgttcacttcccaaatttgtctgcttcttctgttggg gcttctggctgtggagggctcactccatgtcaaacctccacagtttacctgggctcaatggtttgaaacccagcacatca atatgacctcccagcaatgcaccaatgcaatgcaggtcattaacaattatcaacggcgatgcaaaaaccaaaatactttc cttcttacaacttttgctaacgtagttaatgtttgtggtaacccaaatatgacctgtcctagtaacaaaactcgcaaaaa ttgtcaccacagtggaagccaggtgcctttaatccactgtaacctcacaactccaagtccacagaatatttcaaactgca ggtatgcgcagacaccagcaaacatgttctatatagttgcatgtgacaacagagatcaacgacgagaccctccacagtat ccggtggttccagttcacctggatagaatcatctaagctcctgtatcagcactcctcatcatcactcatctgccaagctc ctcaatcatagccaagatcccatctctccatatactttgggtatcagcatctgtcctcatcagtctccataccccttcag ctttcctgagctgaagtgccttgtgaaccctgcaataaactgctttgcaaattcctgcaggcagcata agttttcatcc agagtttggatctaaccagcaaaactctgtcttacacaggatgacttggaattagagtccttatagcagaaagagcagca gggctgtccttgggtatccgttgctcagccaagtcatcaaataaaaaggatgattgcacaagtggactatgtaccaatct gtgggtttctgcatggccaagagccagaccctccctctgggctctgctggcccaacccaccaagggatgctttatttaaa cagttccaagtaggggagaccagctgcccctgaaccccagaacaaccagctggatcagttctcacaggagctacagcgcg gagactgggtaagtcaacgatccccagagctgggacagaaggggcagcaatggggcagcaactgagggagaagagagctg acgttagtgcttaggagacgttgcacactttgcagacaggaagtaaaggaaatgggaccccagagtggccgcagaggggc ctgtggggtaagacactacagtgtgtgtcataaccaagacccgatcagggagtagttacttctcttcttttcttacagga aacatggttccaaaactgttcacttcccaaatttgtctgcttcttctgttggggcttctggctgtggagggctcactcca tgtcaaacctccacagtttacctgggctcaatggtttgaaacccagcacatcaatatgacctcccagcaatgcaccaatg caatgcaggtcattaacaattatcaacggcgatgcaaaaaccaaaatactttccttcttacaacttttgctaacgtagtt aatgtttgtggtaacccaaatatgacctgtcctagtaacaaaactcgcaaaaattgtcaccacagtggaagccaggtgcc tttaatccactgtaacctcacaactccaagtccacagaatatttcaaactgcaggtatgcgcagacaccagcaaacatgt tctatatagttgcatgtgacaacagagatcaacgacgagaccctccacagtatccggtggttccagttcacctggataga atcatctaagctcctgtatcagcactcc catca cactcatctgccaagctcctcaatcatagccaagatcccatctct ccatatactttgggta cagcatctgtcctcatcagtctccataccccttcagctttcctgagctgaagtgccttgtgaa ccctgcaataaactgctttgcaaat catctgaaagtgtctgtgtgtcttcattagccgctctgctgtcatttagtgaca a ctactctagagatttttcttcctctaacctgagacttccgggaaacagagagatttgaagataagagacgctttctgt catgaaacagcacagtct atccctctccctgctttaggctgagaagctgaggtctcaaccgatatctagcaactgtcga agactcttgctttgatcaagcttgctgcccctgaaccccagaacaaccagctggatcagttctcacaggagctacaggcc ggagactgggaaacatggttccaaaactgttcacttcccaaatttgtctgcttcttctgttggggcttctggctgtggag ggctcactccatgtcaaacctccacagtttacctgggctcaatggtttgaaacccagcacatcaatatgacctcccagca atgcaccaatgcaatgcaggtcattaacaattatcaacggcgatgcaaaaaccaaaatactttccttcttacaacttttg ctaacgtagttaatgtttgtggtaacccaaatatgacctgtcctagtaacaaaactcgcaaaaattgtcaccacagtgga agccaggtgcctttaatccactgtaacctcacaactccaagtccacagaatatttcaaactgcaggtatgcgcagacacc agcaaacatgttctatatagttgcatgtgacaacagagatcaacgacgagaccctccacagtatccggtggttccagttc acctggatagaatcatctaagctcctgta cagcactcctcatcatcactcatctgccaagctcctcaatcatagccaag atcccatctctccatatactttgggtatcagcatctgtcctcatcagtctccataccccttcagctttcctgagctgaag tgccttgtgaaccctgcaataaactgctttgcaaattc (SEQ ID NO:122₃6) ccatggaggaaggtcaatattcaggtaggaggactctctggttctaacgttggcagaagcaatgacccttagctactcct ttcacccagaagagaagcggggcttcccagtccctctctgggaaagagggtgaatttctaagaaagggactggtgtgagt aaggaggtgaggccgcactgactttcctggcacagagccaggaaggagtggaaaattgagggcccctcctttttctgatt caacaccctcctgacaaaaaaagaaaaagaaaaaaaaaaacggcttcagctagggagcggggacgcaatagagtcagagg ccaaatagaacaggaacttggaacaagcagaatttagcataatgaatcctccaagccagggtgagtgcaga (SEQ ID NO:122₃7) aagcttgggaataagtccagctgggccatgttgtgaggacatggggatgaagtcttagttccaggatggggctgggatgg agtttggtgtttcttttctgtttttctttcttttttcttttcttttttttttttgtgagacagagtttagcttttgttgc ccaggctggaatgcaatggcggatctcggctcaccgcaacctctgcctcccggattcaagcgattctcctgcctcagcct cccgagtagctaggattacaggtgcccaccaccatgcccagctaattttttttttttttttttttttttgtattttcagt agatacagggtttcaccatgttggccttgaactcctgacctcagatgatccacctgcctcggcctcccaaagtgctggga ttacaggcgctgacgatgtgcccggtctctctctctctctttctctctctctttctttcatctcactgtgttgccccagg ctgatcttgaactcctgggctcaagtgatccactcacctctgcctccccagtagctgggatcacaggcatgcaccaccat gccctgctagtttttatagtttttgtagagacaacggcttgctatgttgtccaggctggtcttgaactcccaggcttaag tgatcctcccacctcagcctcccaaagtgctgggattacaggcgtgaacgtccgtgccagccaaactgtccatatttgac ctgaatattatctcacgtatctttctttccccccgcttccctccttccctcctactcctccttctccctctccttccttc tgtcttttttttccccttcctctgcctctctctcctcttcccttttttcttgctgggactcaaacctgggacatttgacc tgggagcctatttgctcaatcatcaagagacataatctcatggtggggtgtctgctggtaagtgccgggtggcaggatcc caactccaggccgtccttctaacccaagaggccctgcctctgcctagagccttccgtggctccccagggccctctgtgat cggccatagtggtatgattcagtgtgcagtaacagtggttcacatcttgacgctaccactcacctccttcagccctgtgg gaacttgctgcttaacatctctagttctcacccaattctcttacctgagaaatggagataataataacacggacttcacc cgggtgtggggagcaccaggagaggccatgcgtgtaatgt atccgggtggcaagcccatatttaggtctatgaaaatag aagctgtcagtggctctactttcagaagaaagtgtctctcttcctgcttaaacctctgtctctgacggtccctgccaatc gctctggtcgaccccaacacactaggaggacagacacaggctccaaactccactaagtgagtacgta ctggtgtgttgg gggttggcccatgggcagtggagatcaaagcgcccttggaagaaacgaccttgggctgagcctcaagggatgaccagcag gaggtcacaaccagagaagggaggtggtgggtggtgagggggcgggggtgggggccgcagtgtggacagaatctcgaggc attcgagtccctgatttggggaagtgaaagcaggccatctggtctgagatgagcttggtgagtgcgctgggccgatcata gagggccctggggagccatggaagactctaggcagaggcaggacctcttgggttagaaggacggcctggagttgggatcc tgccacccagcacttaccagtagacaccccaccatgagattatgtctccagatgattgagcaaatgggctcccagctcaa gggtcccgggtttgagtccagtcccaccactgcgtgatggggacaaatgacttaccctcttggaacctcagttccactga gagaggccccacagaatgaggacagtcccccagcatcctgccagtaggtttactgagcacctactgtgtgctggtgcttt gaatactcccaatttacagatgagcaaactgagctgctcatccagggagaagccaggactcggactcaggtctgtccagc tgcctccctggacagttccagtcccaggatggtctctgggttcctctcacaatgtcaaaagggccagcttgagctgccgc taatcagagcctggccgcgccacaccccacctccctgaggctccgagagaagggacttacctatagtcaagcagcgaaag aaggtagcccgtgacctccaggcctgaaggaccccaagtcccatgctcctcagcacatagtagatgctttaaagtcagag gacttggtcgggcgcaggcacgcctgtaatcctagcactttgggaggctgaggagggcagatcacctgtggtcaggagtt cgagaccagcctgatcaatatggtgaaaccctgtctctactaaaatacaaaaattagccaggtgtggtggtgggtgcctg tagtcccagc acttgggaggctaagacaggagaatcgcttgaacccgggaggtggaggttgcagtgagccaagatggtg ccattgcactctagcctgggtgacagagcgagactccatctcaaaaaataaaaaaataggccatgcacaggctcacgcct gtaatcccagcactttgggaggccgaggcgggcggatcatgaggtcaggagtttgagactagcctggccaacatagtgaa aacccgtctctactaaaaatacaaaaattatctggtcatggtggcacgtgacta agtcccagctactcgggaggctgag gcgggagaatcgcttgaacccaggaggtggaggtggcagtgagccgagatcgtgcccctgcactccagcctgggcaacag agcgagactccatttcaataaataaataaataaataaagtcagagcactttacagatgccctggggacattggcagagga gaaggctgaggcctgggttatgggctcttagcatttctcagtgggacgtggcacagagtagatgtttcataaatgtttag aatctgaagacccactgtgcgcagcccggcaccaaaaacctcaggtatgctgtgatctcattggatcc (SEQ ID NO: 12238) ctcctgcttaaacctctgtctctgacggtccctgccaatcgctctggtcgaccccaacacactaggaggacagacacagg ctccaaactccactaagtgaccagagctgtgattgtgcccgctgagtggactgcgttgtcagggagtgagtgctccatca tcgggagaatccaagcaggaccgccatggaggaaggtcaatattcagagatcgaggagcttcccaggaggcggtgttgca ggcgtgggactcagatcgtgctgctggggctggtgaccgccgctctgtgggctgggctgctgactctgcttctcctgtgg cactgggacaccacacagagtctaaaacagctggaagagagggctgcccggaacgtctctcaagtttccaagaacttgga aagccaccacggtgaccagatggcgcagaaatcccagtccacgcagatttcacaggaactggaggaacttcgagctgaac agcagagattgaaatctcaggacttggagctgtcctggaacctgaacgggcttcaagcagatctgagcagcttcaagtcc caggaattgaacgagaggaacgaagcttcagatttgctggaaagactccgggaggaggtgacaaagctaaggatggagtt gcaggtgtccagcggctttgtgtgcaacacgtgccctgaaaagtggatcaatttccaacggaagtgctactacttcggca agggcaccaagcagtgggtccacgcccggtatgcctgtgacgacatggaagggcagctggtcagcatccacagcccggag gagcaggacttcctgaccaagcatgccagccacaccggctcctggattggccttcggaacttggacctgaagggagagtt tatctgggtggatgggagccatgtggactacagcaactgggctccaggggagcccaccagccggagccagggcgaggact gcgtgatgatgcggggctccggtcgctggaacgacgccttctgcgaccgtaagctgggcgcctgggtgtgcgaccggctg gccacatgcacgccgccagccagcgaaggttccgcggagtccatgggacctgattcaagaccagaccctgacggccgcct gcccaccccctctgcccctctccactcttgagcatggatacagccaggcccagagcaagaccctgaagacccccaaccac ggcctaaaagcctctttgtggctgaaaggtccctgtgacattttctgccacccaaacggaggcagctgacacatctcccg ctcctctatggcccctgccttcccaggagtacaccccaacagcaccctctccagatgggagtgcccccaacagcaccctc tccagatgagagtacaccccaacagcaccctctccagatgcagccccatctcctcagcaccccaggacctgagtatcccc agctcaggtggtgagtcctcctgtccagcctgcatcaataaaatggggcagtgatggcctccc (SEQ ID NO:122₃9) agtggctctactttcagaagaaagtgtctctcttcctgcttaaacctctgtctctgacggtccctgccaatcgctctggt cgaccccaacacactaggaggacagacacaggctccaaactccactaaccagagctgtgattgtgcccgctgagtggact gcgttgtcagggagtgagtgctccatca cgggagaatccaagcaggaccgccatggaggaaggtcaatattcagagatc gaggagcttcccaggaggcggtgttgcaggcgtgggactcagatcgtgctgctggggctggtgaccgccgctctgtgggc tgggctgctgactctgcttctcctgtggcactgggacaccacacagagtctaaaacagctggaagagagggctgcccgga acgtctctcaagtttccaagaacttggaaagccaccacggtgaccagatggcgcagaaatcccagtccacgcagatttca caggaactggaggaacttcgagctgaacagcagagattgaaatctcaggacttggagctgtcctggaacctgaacgggct tcaagcagatctgagcagcttcaagtcccaggaattgaacgagaggaacgaagcttcagatttgctggaaagactccggg aggaggtgacaaagctaaggatggagttgcaggtgtccagcggctttgtgtgcaacacgtgccctgaaaagtggatcaat ttccaacggaagtgctactacttcggcaagggcaccaagcagtgggtccacgcccggtatgcctgtgacgacatggaagg gcagctggtcagcatccacagcccggaggagcaggacttcctgaccaagcatgccagccacaccggctcctggattggcc ttcggaacttggacctgaagggagagtttatctgggtggatgggagccatgtggactacagcaactgggctccaggggag cccaccagccggagccagggcgaggactgcgtgatgatgcggggctccggtcgctggaacgacgccttctgcgaccgtaa gctgggcgcctgggtgtgcgaccggctggccacatgcacgccgccagccagcgaaggttccgcggagtccatgggacctg attcaagaccagaccctgacggccgcctgcccaccccctctgcccctctccactcttgagcatggatacagccaggccca gagcaagaccctgaagacccccaaccacggcctaaaagcctctttgtggctgaaaggtccctgtgacattttctgccacc caaacggaggcagctgacacatctcccgctcctctatggcccctgccttcccaggagtacaccccaacagcaccctctcc agatgggagtgcccccaacagcaccctctccagatgagagtacaccccaacagcaccctctccagatgcagccccatctc ctcagcaccccaggacctgagtatccccagctcaggtggtgagtcctcctgtccagcctgcatcaataaaatggggcagt gatggcctcc (SEQ ID Nθ:12240) ccatggaggaaggtcaatattcaggtaggaggactctctggttctaacgttggcagaagcaatgacccttagctactcct ttcacccagaagagaagcggggcttcccagtccctctctgggaaagagggtgaatttctaagaaagggactggtgtgagt aaggaggtgaggccgcactgactttcctggcacagagccaggaaggagtggaaaattgagggcccctcctttttctgatt caacaccctcctgacaaaaaaagaaaaagaaaaaaaaaaacggcttcagctagggagcggggacgcaatagagtcagagg ccaaatagaacaggaacttggaacaagcagaatttagcataatgaatcctccaagccagggtgagtgcagaaagcttggg aataagtccagctgggccatgttgtgaggacatggggatgaagtcttagttccaggatggggctgggatggagtttggtg tttcttttctgtttttctttcttttttcttttcttttttttttttgtgagacagagtttagcttttgttgcccaggctgg aatgcaatggcggatctcggctcaccgcaacctctgcctcccggattcaagcgattctcctgcctcagcctcccgagtag ctaggattacaggtgcccaccaccatgcccagctaattttttttttttttttttttttttgtattttcagtagatacagg gtttcaccatgttggccttgaactcctgacctcagatgatccacctgcctcggcctcccaaagtgctgggattacaggcg ctgacgatgtgcccggtctctctctctctctttctctctctctttctttcatctcactgtgttgccccaggctgatcttg aactcctgggctcaagtgatccactcacctctgcctccccagtagctgggatcacaggcatgcaccaccatgccctgcta gtttttatagtttttgtagagacaacggcttgctatgttgtccaggctggtcttgaactcccaggcttaagtgatcctcc cacctcagcctcccaaagtgctgggattacaggcgtgaacgtccgtgccagccaaactgtccatatttgacctgaatatt atctcacgtatctttctttccccccgcttccctccttccctcctactcctccttctccctctccttccttctgtcttttt tttccccttcctctgcctctctctcctcttcccttttttcttgctgggactcaaacctgggacatttgacctgggagcct atttgctcaatcatcaagagacataatctcatggtggggtgtctgctggtaagtgccgggtggcaggatcccaactccag gccgtccttctaacccaagaggccctgcctctgcctagagccttccgtggctccccagggccctctgtgatcggccatag tggtatgattcagtgtgcagtaacagtggttcacatcttgacgctaccactcacctccttcagccctgtgggaacttgct gcttaacatctctagttctcacccaattctcttacctgagaaatggagataataataacacggacttcacccgggtgtgg ggagcaccaggagaggccatgcgtgtaatgttatccgggtggcaagcccatatttaggtctatgaaaatagaagctgtca gtggctctactttcagaagaaagtgtctctcttcctgcttaaacctctgtctctgacggtccctgccaatcgctctggtc gaccccaacacactaggaggacagacacaggctccaaactccactaagtgagtacg atctggtgtgttgggggttggcc catgggcagtggagatcaaagcgcccttggaagaaacgaccttgggctgagcctcaagggatgaccagcaggaggtcaca accagagaagggaggtggtgggtggtgagggggcgggggtgggggccgcagtgtggacagaatctcgaggcattcgagtc cctgatttggggaagtgaaagcaggccatctggtctgagatgagcttggtgagtgcgctgggccgatcatagagggccct ggggagccatggaagactctaggcagaggcaggacctcttgggttagaaggacggcctggagttgggatcctgccaccca gcacttaccagtagacaccccaccatgagattatgtctccagatgattgagcaaatgggctcccagctcaagggtcccgg gtttgagtccagtcccaccactgcgtgatggggacaaatgacttaccctcttggaacctcagttccactgagagaggccc cacagaatgaggacagtcccccagcatcctgccagtaggtttactgagcacctactgtgtgctggtgctttgaatactcc caatttacagatgagcaaactgagctgctcatccagggagaagccaggactcggactcaggtctgtccagctgcctccct ggacagttccagtcccaggatggtctctgggttcctctcacaatgtcaaaagggccagcttgagctgccgctaatcagag cctggccgcgccacaccccacctccctgaggctccgagagaagggacttacctatagtcaagcagcgaaagaaggtagcc cgtgacctccaggcctgaaggaccccaagtcccatgctcctcagcacatagtagatgctttaaagtcagaggacttggtc gggcgcaggcacgcctgtaatcctagcactttgggaggctgaggagggcagatcacctgtggtcaggagttcgagaccag cctgatcaatatggtgaaaccctgtctctactaaaatacaaaaattagccaggtgtggtggtgggtgcctgtagtcccag ctacttgggaggctaagacaggagaatcgcttgaacccgggaggtggaggttgcagtgagccaagatggtgccattgcac tctagcctgggtgacagagcgagactccatctcaaaaaataaaaaaataggccatgcacaggctcacgcctgtaatccca gcactttgggaggccgaggcgggcggatcatgaggtcaggagtttgagactagcctggccaacatagtgaaaacccgtct ctactaaaaatacaaaaattatctggtcatggtggcacgtgactatagtcccagctactcgggaggctgaggcgggagaa tcgcttgaacccaggaggtggaggtggcagtgagccgagatcgtgcccctgcactccagcctgggcaacagagcgagact ccatttcaataaataaataaataaataaagtcagagcactttacagatgccctggggacattggcagaggagaaggctga ggcctgggttatgggctcttagcatttctcagtgggacgtggcacagagtagatgtttcataaatgtttagaatctgaag acccactgtgcgcagcccggcaccaaaaacctcaggtatgctgtgatctcattggatccctcctgcttaaacctctgtct ctgacggtccctgccaatcgctctggtcgaccccaacacactaggaggacagacacaggctccaaactccactaagtgac cagagctgtgattgtgcccgctgagtggactgcgttgtcagggagtgagtgctccatcatcgggagaatccaagcaggac cgccatggaggaaggtcaatattcagagatcgaggagcttcccaggaggcggtgttgcaggcgtgggactcagatcgtgc tgctggggctggtgaccgccgctctgtgggctgggctgctgactctgcttctcctgtggcactgggacaccacacagagt ctaaaacagctggaagagagggctgcccggaacgtctctcaagtttccaagaacttggaaagccaccacggtgaccagat ggcgcagaaatcccagtccacgcagatttcacaggaactggaggaacttcgagctgaacagcagagattgaaatctcagg acttggagctgtcctggaacctgaacgggcttcaagcagatctgagcagcttcaagtcccaggaattgaacgagaggaac gaagcttcagatttgctggaaagactccgggaggaggtgacaaagctaaggatggagttgcaggtgtccagcggctttgt gtgcaacacgtgccctgaaaagtggatcaatttccaacggaagtgctactacttcggcaagggcaccaagcagtgggtcc acgcccggtatgcctgtgacgacatggaagggcagctggtcagcatccacagcccggaggagcaggacttcctgaccaag catgccagccacaccggctcctggattggccttcggaacttggacctgaagggagagtttatctgggtggatgggagcca tgtggactacagcaactgggctccaggggagcccaccagccggagccagggcgaggactgcgtgatgatgcggggctccg gtcgctggaacgacgccttctgcgaccgtaagctgggcgcctgggtgtgcgaccggctggccacatgcacgccgccagcc agcgaaggttccgcggagtccatgggacctgattcaagaccagaccctgacggccgcctgcccaccccctctgcccctct ccactcttgagcatggatacagccaggcccagagcaagaccctgaagaccoccaaccacggcctaaaagcctctttgtgg ctgaaaggtccctgtgacattttctgccacccaaacggaggcagctgacacatctcccgctcctctatggcccctgcctt cccaggagtacaccccaacagcaccctctccagatgggagtgcccccaacagcaccctctccagatgagagtacacccca acagcaccctctccagatgcagccccatctcctcagcaccccaggacctgagtatccccagctcaggtggtgagtcctcc tgtccagcctgcatcaataaaatggggcagtgatggcctcccagtggctctactttcagaagaaagtgtctctcttcctg cttaaacctctgtctctgacggtccctgccaatcgctctggtcgaccccaacacactaggaggacagacacaggctccaa actccactaaccagagctgtgattgtgcccgctgagtggactgcgttgtcagggagtgagtgctccatcatcgggagaat ccaagcaggaccgccatggaggaaggtcaatattcagagatcgaggagcttcccaggaggcggtgttgcaggcgtgggac tcagatcgtgctgctggggctggtgaccgccgctctgtgggctgggctgctgactctgcttctcctgtggcactgggaca ccacacagagtctaaaacagctggaagagagggctgcccggaacgtctctcaagtttccaagaacttggaaagccaccac ggtgaccagatggcgcagaaatcccagtccacgcagatttcacaggaactggaggaacttcgagctgaacagcagagatt gaaatctcaggacttggagctgtcctggaacctgaacgggcttcaagcagatctgagcagcttcaagtcccaggaattga acgagaggaacgaagcttcagatttgctggaaagactccgggaggaggtgacaaagctaaggatggagttgcaggtgtcc agcggctttgtgtgcaacacgtgccctgaaaagtggatcaatttccaacggaagtgctactacttcggcaagggcaccaa gcagtgggtccacgcccggtatgcctgtgacgacatggaagggcagctggtcagcatccacagcccggaggagcaggact tcctgaccaagcatgccagccacaccggctcctggattggccttcggaacttggacctgaagggagagtttatctgggtg gatgggagccatgtggactacagcaactgggctccaggggagcccaccagccggagccagggcgaggactgcgtgatgat gcggggctccggtcgctggaacgacgccttctgcgaccgtaagcfgggcgcctgggtgtgcgaccggctggccacatgca cgccgccagccagcgaaggttccgcggagtccatgggacctgattcaagaccagaccctgacggccgcctgcccaccccc tctgcccctctccactcttgagcatggatacagccaggcccagagcaagaccctgaagacccccaaccacggcctaaaag cctctttgtggctgaaaggtccctgtgacattttctgccacccaaacggaggcagctgacacatctcccgctcctctatg gcccctgccttcccaggagtacaccccaacagcaccctctccagatgggagtgcccccaacagcaccctctccagatgag agtacaccccaacagcaccctctccagatgcagccccatctcctcagcaccccaggacctgagtatccccagctcaggtg gtgagtcctcctgtccagcctgcatcaataaaatggggcagtgatggcctcc (SEQ ID NO: 12241) gtaagtatcttccctctgtggctaggaagacaaggaatacatttttaaatgtctcctaaagcaaggacctgaaaccagct ctatgggattattcttgttcctctttggtcaatgcagagacatgggaagaaccaccaaaggtcatgagggtctcttccag ggatccctggacattgcctttcccagtggtgtgacaagagttagaggtggcctaccttgcctcctgtcctaggaggcgac agtaggagagccttcggttttctcatcctcttacttgtatgttgaactttacttaatgcaggctatatccaaaatacagt gtgaattaggctagaatagaaatgctttctattctaccttcagaaaaggaaaagggtagggtaggggaaatcatgggaga gattaaaggcagagaggaaacccagatgggactgtttaatccccaagcaagaaaccactaggaaagagagataccttccc tctaacttttgtattcggtgcactgacattgctctctgtgctggtgggaaattgatttctgtgccaggatgttctaggct gaggccaagagggtgctggccctttacccagtggaagaaaaaggcaagggtgaggctttgtagactttcccattcggagg taatgatgcctccttcagccccacttcttcaaactgactccacctgctcccatctccacacccctccgtttctcatttag ccaaagcacatcatccttgcagcccaccactcagcttggccaggtgcgagacatctttccccacttcatacctcccctcc ggccaggtgatgtttgcctcctcag (SEQ ID NO: 12242) gatcacctgaagtcaggagttcgagaccagcctgaccaacatggagaaaccccgtctctactaaaaatacaaaattagtt gggcatggtcgtgcatgcctgtaatcccagctactcaggaggctgaggcaggagtatcacttgaacccaggagacggagg ttgcggtgagccaagaacatgccattgcactccagccttggcaacaagagcaaaactccgtctcaaagaaaaaaaaaatt tttttttgtcaacccatgtgggtatgaaattgtttctcattatttgcatttcactaatt ctagtgaggtcaaacatttt ttccctcatttcttatccattaaagtttattctgtgaattgccagttcatggccattttgggggtgtagtttttcttact gatttattgaagtttaatgtttttctggaaactaatattttgctagttgtgtgaattgtaaatatcttctcccactgtat ttttttaaaaactttttattgtctgaattagcacatatttagtgaatgcctctatgtgcaattctttttttttttttttt tttttttttgagatggagtttcgctcttgtttcccagactggagtgcagtggcatgatctaagctcactgcaaccttcac ctcccgggttcaagtgattctcctgcctcaggcctcctgagtagctgggattacaggtgcccgctaccatgaccagctaa ttttttgtatttttagtagagacggggtttcatcatgttggccaggttggtctcgaactcctgacctcaggtgatccacc cgcctcggccttccaaagtgtagggattacaggcatgagccagtgagctcagcctctatgtgcaattcttaatgtcaagc tgagggagaagtctaagaagttttatataagtctgacacccagggtgcctgtaattaaaggtggaatgaaattttaattt gcgagttgatccttctgttttttagttcagtacttcctcctttttagaatgtatgctttccagataattagtgagataaa gatttgattttcacttttagcatttctaaaagctgtaatatgctacctaacttgtttttaattcttgctctaacttctga tattttatagttgtgtattttgaattatattttaaaggattaagtggattattgcacatgatatttagtaaagtgtttgg gagcatttagcacagcctccaaaaattagaattccactagccccctgatcctacatatctggcatcttaagagtcaataa tagcaaagttgagagaggcagcttggtgtggtggaaagaacatgggtattggatccgatagccttaggttcaaatcctgg cttcttcagtaattatcttctgtaattttagccaagtgtttaatttccttgagactcagtttctcgaagatgaagtagaa aatggctttcaccaggttgttgtaaagactgaatcaaatagtgtgcatgaaaattgcaaggcatagtgctcaggacatag ttaacattcttaaatatatgttgaggaatggtgtgcacctgaaaattcctataaaagctgcaaatatacatgccttttga tccagctgttccacttcaggata ccttactcatgtgtgcaaagcaattttttgtagaaatgtttgtaatagcaaaagac tggaaacaactgaaatgtacactgctagggaactgattac ctctggtatgtccacgcaatgcagctctatgaaaaaaag gagtacgtgtcaagatatattaacaaataaagtacagaatattgtactgtacttatcccttttgtgtttaacaaaagaaa gaaaaggagaaaaattagaatatagt tatatttgcctttatgtgcaaaaaaaggaaatcactttttgttttttttgaga cagggtctcattctgtcacccaggctggggtgcagtggcgctatcacggctcactgcaacctcaacctcccaggctcaag cgatcctcccgccacagcctcccaagtagctgggactacaggcacacgcgccatgcccagctaatttatttatttatttt tggtagagatggggtttcgcgatgttacccaggctggtctcaaactcctgagttcaggtgatccacctgtcttggcctcc caaagtgctctgggattacaggcatgagccactgtgcctgacctcttttcttcttgatgtgaaattcttcatagattaga caaatttgcccattgtgcaaatatgttgcaaatatattttctcagtttgtcatttatcttgatttttcttatggttttaa aaaaatgtgattggatttatggtttctggcattgaaccatagttataaatgtattctttactctgaggttgtccagggaa tcttctaattttcttaatttaattttcatcttttaaaaacagctctattgatgcataattgatatacaaaaatagcatat atttactactatttgatgagtttggacatgtgtacacacccatgaagccatcagttaacctgatggtggtgatggtttcc tgtaattttatgcttccatttttcacatttagatctgacttttctggaatttatctaagtgcacgatgtgaaagatagat acagcttatttttctttccagatggctataccttgttctaggacaatttattaaatagtccatctttttctttctgatct gagatgctatctttat atatgctaaatttctgtacatgtttaaatttatttgctccttttgtttgtctctttgtacacc agtatctacctcattgttctaattattcgagcttcaggatacattttaatacttctgggtaggaacagaaccttctcgtt actcttacaaaattttcttctttattctggtttatttttcctaagaactttaaaagttggcactgaattccaaaatagaa cacccaaaaacctgttgatttttccactgggattatgttaaattttcgggttaacttaggggaaaaccattatttcatga tgttaaatcttactccatgagagagcatggtacgtcttttcatctgtacaggtctttttttatattgttcagtagcaatt taaaaaaatcatccactatgttcaatgaaataaaaggccagatttaaaaatttggcaaggagttgaaaactataaaaagg aaccaaataaaaattctttttttgcccccataaggcagaagaaatacaaattctacaactgaaaaaatataatatctgat attaagaaatcaataaatggtttattatattagctacatttgaagagacaactaaaaaagaaaaatattttcaaaccaac tcagaaacaagaagatggaaaataaagaatacaatgctatttatatttatatataatagtatatataatacacaagttta acataggactgcatttgcagaatagaagagagataatggggagatagcaacacttggagaaaaaataacgaacacttttt ta ttaaagtgcctaacttggctgggtgtggtggctgacacctgtaatcccaacactttgggaggctgagatgggtggat catttgagcccaggagttcaagaccaacttgggtaacatggcgaaaccccatctctacagaaaaactccaagaaataaaa aacaataatcatctgagtgtggtagcacatgcctgcgtccttgctactcaggaggtgggggtggcagaattaccagggcc tggaagtcaaggctgcaatgagctgtgatcgcatcactatacttcagcctggttgacgagtgagaccctgtctcaacaaa taaaaataaaaataaaaataaaaatgcctaacttggtgcttggcactttctaaaattgacacataatatttgtacctgtt tatggagtatatgtgatattttgatacatgcatacaatgtgtgtaatgatcaaatcaggatatttaagatatccatcatc tcaaacatttttctttgtgttcagaacattccaaatctagctattttgaaatatacaataaattattaactatagtcatc ctaatgtgctattgaatattattgaattccatctaattatatgtttgtaccaattaaccaatctctacttattcctcacc cccagctcccaccaaccctttccagtctctggtaactatcattttattctctacctccatgagatcaaattttttacctc ccatatcgttgtcaatattattatttttcccaccctggctcctaatgaaggatttat gacaatatcactggaatctaaa tcctctaggccattttttcaccaatgcccttattttcttagggcttttttttttcttaaatcaacagttttaatgagata taattcccattctataaaatttcctcgtttgaagtgtacagtttaatagcttttagtatatccacagaagtgtgcaacca tcaccataataaattttaaaacattttcagcagggcgcagtggctcacgcctgtaatcccagctactcaggaggctgagg caggagaattgcttgaacccaggaggcagaggtttcagtgagccgagattgcaccactgcaatccagcctgggccacaga gtgagactccatctcaaaacaaaacaaaacaaagcaaaataaaacaaagcaaaataaaacaaaaccaaaacccaacaatt ttgaacattttcatcttaccaccctgccaaaaatccctgttctccttagccatcaatcttcagctccctacccacttcta accatgaatctattttgtagatttgtctattctcgatatttcatatgaatgaaataa ataatatatggttccttgtgac tagtttctttcacttagtatgtttccaagttcatccatgttttggtatgtatcagtacttcattcctttttatcatggaa taatattctgttgtattgatat ctacgtttcattcattcatctgaacatttggattatttccatttttgtctattataa taattctgctatgaacacccatgtatacgtttttgtgtggacatgatttcattttccttggatatacacctagcagtaga attgttgagtcataaagaactctaggtttagctttctggggagcttccagattattttccaaaatggctgtgccatttta cattcccaccagtaaagtatgagggttctaatttttccctgtcttcaccaatacttgttgttatctatcttttttattat agtcatcatagtctgtatgaagtgatttctcactgtagttttttcagtagtaattaaaaaatttcctacctattttagcc taaaattactttcctgactctcttcaaggagcctgccagagaattctctctctcgtgctgtctcccttatgcctgggcat aagctctgataatgccctgtctgggaaaactcttttggccttctcaatttctattacattgagagcccaagaacccatgg tcagtaacaggccaatgagaagcctcctgcattagtctaggtgaaggataatggtggcttggaccggaatagggtggtag tcatggaaatggggagaatttgacagactagatttattttggaaatagaactgaatctgaacagattgaattgggcaggg agcagggaaagtgaaggggaaggaagacaccaggtttatgccttcagcatttgggtggatgaatggatggatgaaaggat agatggatgcatggatggtggttggatggatgagtggttggatgaatggacggtcaaggggtgaatagatgggtggatgg aaaatggagagatgatgaactgagatggggaagactagaagtggggcatatttttggggaaagacagttttgcaatacgt taagtttgaggtgcctcagagtcataagagaggatttgtcagaaaggcagttggatataagattttgaagctcaaaagac agggagggcctgatggtatgtttaaacctatacggatatcacataggtaacatttcaagcctaagaaatgggccgggcgc agtggctcacacctgtaatcccagcactttggaaggctgaggcgggtggatcacttgaggtcaggagttcgagacaaacc cagccaacatggtgaaaccccatctctgctaaaaacacaaaaattagtggggcatggtggcacatacctgtaggcccagc tactcaggaggttgaggtgggagaattgcttgaacccgggaggcagaggttgcagtgagccaagattgcgccactgcact ccagcctgggcgacagagcaagactccgtctaaacaaaacaaaacaaaaaaagccttagaaatgggcaatgccaccaaag cagaaagatgaaaggagggcaatgccctgaggtgtgccagcattggaggaaacaaacagccagagatgtaggaggaaagc ccagagaaactgtgagctgcaaggatgaagtagtaacaaataaaatgccaccaagagaaccagaaggacgactggaaaca aataaacaagaaagactattgcatttagcaacgtgaaaacgttggattactttttactcagaaatcaaaccccaaggata gtgtttcccctccctacggggtttctgcaggtccctttacacgcccccttctacttctttaagtgctaaaagtgattaat ttggggtgatgttttaatttctattctttttggcttataactgtgttttttcattctttgcaacaacagatagtatgttg taatagaaaaatccattgtggtcaatgataacttctgcctgttcctgggcacagggggcatcactattagtgcctgttcc tccctccctactgctgataaggaaacaggggcaggaataatactaataatttgtgctactttttctgcatacccttggcc ttattctggtctactgagctgggagcttgtctgaggctggagctctattgtctgaatccaggggcagaaagaactgaggg ctcttttacggcatccacctggaggctgcctgcaggcttgggttgctaagtgcactgcttaatttagaagcgccttttat cctggctctcttgaccagtcaaagttgtggtcgctgttttctacaaggactggggaaagaaagggtggaattaattaaac ctggaggaagggactttgaagggcggagctaaggtcaaagaaagaaccctttaaataaagggcccacactggctgccagg gagtgcgcaggactggcaagagggaagccgggctgctccacgcctttcacgccttccacctcctgcgtgtccatctgtga gaaggagccagagcccaagggagatgatggagcctgaggagtacagagagagaggtgagcaacgggcatccctggccctc ttccctgctgctactcctgcaggaacggctgctggtgggtggcccttagattgtggggtgacatttgatgggagcattag aattgccttctgagagttggcaccagcaacatttttttttctgcgaaaggaatgtgggatcagagtgtaaaacttttctc aaccactctttcattctccctctcatatacccactctcacatatgtccacactaccgtgccttgcttttcctccccactt tcccacaaaattgaggatttggatccctgagccactagatgggaaaaggggattgttcatattctgaaatagaaaaaaat tttctcaatattctgtaatcactgcaaatcctttctttcttaacattcattccttcatgtgtgaatctatcagcagtgtt ctttcatttagtcattcatttcataaatatttagtaggtgcctactctgtatcaggcaaaaccaagtggttatccagttc tcaggcatggatctcccttagcaggaaagtaggtagttgcttaaaaaagaatcttgaatgtctatttctataatgtttta tatcctcctactcactaattagtgtgcgttagcttattccattgctttcctaaggcactgtcagctgagagcaagttcct gtggatatttatcttctgagtggaacacaaatacatttagcactgttcctggatcagtggagggttaggtctagagctct cagatctctggtggggccctgctggagaagaaccaggatgtgagagggttgaaggggagcagaaggaagatagaatggtg tggaaatctacctttgtctcataagttttgtctggggttggttctgttcttaagaactttgcataagctgatgcagaggg gagaaactgagtcccctctcctaggtaaaagcagcccagggagtactaaggaatggatgttgagacagacaaagagatat gtacacacacacacatgcacacacagcaacagaggcactgaagactgcaatctgaaagaataaataatttgcaatagttt cagagtgttcaacttgacttttttttccttccttactcatatgttcattcacttgatacatttttttttagcatctaaaa aatatcctaagcactgaggtgttgatggaggcagcaggagggagagaaagtcattaagatttggtgccacatttcccagg ccagggcagggggcttggtctggatccatggttgtgctttagggattctgtgagcctcagaaattatacacaaagttctg tgtatatgtaagcctacagttttaatcagattcttgaattaagtcctcatatgagtccaaaaaagatgaataataactga ttcaatggggatggtgaaaaaatagatttttttgtccttt tcggaactgggcatggaatctttctatctgtgctaacag atataactggtgggtgtgtgtgtaacaatttttggatacaaagagctatagagtttctattgaacctataaaatagttaa tagatgttctgtttctgagaaggaaagaaaggtaggagagacaatcaaaattgaagtggataaaggaaggggaaagaaaa tgaaacgtttcactttggcgctagagttttgtgctttggagattttcctttttgttcatttgctcacttagaaactccct ccatcattcattcactccctcactctttttttaaattctgaagataaggtcgtgcaggggatcagatcctaccctcggcc catgaatctgtctctctcttttttttgagtccaggctggagtgcagtggcacgatctcggctcactgcaacctccgtctc ccaggttcaagcgattctcctgcctcagcctcccaagtagctgggattacatgcgcctgccaccacgcccggctaatttt ttgtatttttagtagagaggggtttgaccatgttagtcaggatggtcttgatctcctgacctcgtgatccgcctgcctca gcctcccaaagtgctgggattacagg^'catgagccactgtgcccggccaaatccatctccttctttaccaagtctcttggc ccggacctgagagggatgggcacaaatcggtcaggcccagtcaggggatttcagcctgatttctctatgtcacttctagg gagagagatggtggattacatctgccagtacctgagcactgtgcgggagagacgtgtgacgccagacgtgcagcctggct acctgcgagcccagctgcctgagagtgctcctgaggaccccgacagctgggacagcatctttggggacattgaacgaatc atcatgcctggggtgagacacagtgaccacaagggcagttctggatttcagggcacagaagggtgggtggtggcctggag aaagacctgctttgggtcagcttgggatgagaatgcatccttcagccacttggccaccaacaccccagcccatctgctag gcatgtggagggcaggactttgactggtattaggtttctttttctttttttttgcccagttgtgccatggcatgaggttt ctgatgccagggcagggctggccagaacacctgcattccagagcacagcctggcagaagtgtggaagtctaatgggatgg gtggagaagtgaacattttgtctgaggggaaaggacactgtgtatagtaagacaggggagaggaagctggtggtagtgcc tggccctgacgacggagccagagactcttctgtacagtgtctgagaccacaccaaagagaaggaaggaagtggggaacac atcctggcaaggacacgctggtgaccaggttgcgttggcccaggaaactgagtgggccctggcaacccctcctgtcccct ctgaggtctggtgattgagctgcttttcaagagcaagaagggactttccctgaatcattgatactttccatgatggaggg tgcagcctgggatagtgctggtggggccaggaagctgatggaagctggctgatgcatgggcttgagctggagcctgcctt gatgggtggtggacacccctgaccactggcggtgaggagctctgccatggtgctcatgctaaagtggcatcgactccctt cctgtggcggggctccctgccatgtgccagctctgtgctggccacatgacatgctatctaatttaatcttcccagtggcc ctgttttacagatgaggaaactgctgatgctcagagaagttaactgtcttgcccaaagtcacagaattagtacctggtag atccaggattttaccctagaccagtcttacttcacaggctgtgccgtttctcctaccccctgtcacctctactggtgggt gcctgaatgtgcctggctaagcctgggcccctagcattgcctgtctggctccacacccccacacaagctgtgtcttccct ctccctgcttggggcatttgtgttctgaaccacacatgtttagaggctcttcctgaggccagcttgaggtttgccttcat cattcccaaagaacttttgacttcaatgtgacaaaaaggccaggcgcgggggctcacacctgtaatcccagcactttggg aggccaaggcaggtggatcacctgaggtcgggagttcaagaccagcctgaccaacatggagaaaccccgtctctactaaa aatacaaaattagctgggcatggtggcacatgcctgtaatcccagctacttgggaggctgaggtaggagaatcgcttgaa cccgggaggcggaggttgcggtgagctgagatagcgccgttgcactccagcctgggcaacaagagcgaaactccatctca aaaaaaaaaaaaagtgacaaaaatatgcctagaggcaggggtgggaaaatattcaaactcagaaagtgatggcaattttg acttttttttttttttttttttgaagcaatagagacaaggtcttgctatgttgcccaagctggtctccaactcctgggct caagtgatcctcctgcctcggccttccaaagtgttgggatgagaggcctaagccactacgcctggccatgagggcaattt catacaaagccactcatctctttgaccattcagcctatttcacaagcattttttgaaaatgtcaatatcagtaaggcttt acggaggctagatcctgataagattatctcctggattttattctgtaaaatgtaatctgctgaggggctaactgtaatct gggagtgagactgaaagcaactgtcagaagaggtggaaatgagctgattcatttgatcaagaggaattccagcagttgcti gtgggtatggtcggtgaggctcatttctggaaagaggtctgtttgtttttgataagggctcttctggctattttatctta tttatcttacaagaacagactattgtctcttgatagagctaggaggtagaagcccttctctggggtttccaaaatactgt cactaaggacagtgataatgatggtcaaatctctcaactcatctctcaggccacaccagcctctgagagctggcctgaaa gcagttggccctttgcttactcattttgctcagtgcctcattgaaaactgaattagtttttctcttcctgccaccaccta gaaaataagagaagaagaaaaactctctttcccctttaattccaaccctggttagacaatcctcatttacttttcatgag agagagagagcatccccacgggaaaagtcaggacaccaccctgctcgggtgtctgggcttctgcctcattgcggtcacct gtccctatggggtatgtgtgaccacagggatgtggcctctctctgtcagccccagttctcgcctgcaaaacagagataat gtgtaggtcctaccccatagggtcctgtgagaagtaagtaagagaaggcttggagagcaggagatgtggttattaccgat catgactcttacatggtgaaaattggaggaagaggtttgattctctgagtcaagtcaggatatgtgatgtgtctgtcacc cacatgattagtttaccgttaatgttagagcttaacatttcacacatttcttgcccacgcctccacccacacaacaaccc taggagacaggatttattttacgatgagaaactgaggttgagggaggtgcaggagaggctcctggtcttatggggtctgt actgtaaacactttttgagacctccttttgaaaaacaaaaaagaaggaggccggacacagtggtgcacgcctgtaatccc agcactttgggaggctgaggcgggtggatcatgaggtcaggagttcgagactagcctggccaacatagtgaaacactttc tctattaaaaatacaaaaaattagccaggcatggtggtgggcacctgtaatcccagctacttgggaggctgaggcaggag aatctcttgaacctgggagccaggggttgcactgagccaagatggcgctgctgcactccagccctggtgacagtgcgaga a ctgtctcaaaaaaaaaaaaaaaagaatgaatctcaaaagagacccacacaaatggtatgttggagcttaagttcatta gcttcatggtaaatctacacggtcacacagctggttagggactgaggtgggatgggaacttgtgtccttggacttaattc ttaggctccttatactatacacactgtccaggacaaggtccttgctcttgaaggactctaagtatgtgtggacagtaaag aacaggatgatgccctaagatgttatcaaatgagtcctcagtagagtgaaacatctagaattctagagttctatcgctca gggaagggatcgaagggagctgtgggagctgggggagagttcgaggaggaaatgaatatttagtagctttctaagaactg gcaggttttggaaggtcatgtctttatagagagtgcctttctatcaggggacacagcattgctcaaagacataaatgcag aaaggaacagggcatgcttcagagcagtgagatgaggagagatgagataatccatgaggccgatgaaccaccagggctgc ttctgagttctgatggggggcccttcctgcccactcagctcctccttacatccggttttgattgtgggctcagggcttag cctggaggtcggcctcccatacgcttggtctgggctctcctctctaccgtctcctttcctcactacattcccaatgtgat gcttaaggacagctttgaacccattcacccagaccctctgagttgcatgctcagggagctcagtgctccataaaacaaaa acaaaaggtgccttttgcaagaaactggatgaaacaagtagtctgcttttctggagctcacagtctgcccttcctttttt ttttttgagacggagtcttgctctgtcgcccaggctggagtgcagtggagcgatcttggctcactgcaagctcagcctcc cgggttcacatcattctcctgcctcagcctcctgagtagctgggactacaggcttctgccaccccgcctggctaattttt ttggtatttttagtagagatggggtttcaccatgttagccaggatggtctcaatctcttgatctcgtgatccacctgcct cggcctcccaaagtgctgggattataggcatgagccaccgcacccggcctgcccttccttttattgctgggcaggggcgg catgaggggtaagtactggggactaatgtgaataccacccagaatcccacaactgggttactgtagtgattttccttttg catatttccttctggactttgcatatatgaaaaggctccactgatgatctagcataggacatgggccacattagtgacaa gaacaccagtgaacaagtctgattttcatggagttatgtcacttatttctgcttaaaagtgtcagcccatctctagagtg acacttcaccttgccagagatggtctctggagaaagaaagcctgctggaaatgcctcctggtgccaactctgtgcatgct ctgcctccaggtggtacattggcagagcccccatatgcacgcctactacccagccctcacctcttggccctccctgctag gagacatgctggctgatgccatcaactgcttgggattcacctgggtgagtagcaacggctgtaactactcgcaatgggga acgtagcagggagtggtatcctagggcagacatattttgtcttggtttctgaatatggctccacaataaatattaatgag ggctatattctttaagcttacgctttattttaattttctcatcacatcctttaaccctatggaatcacgagtattgatcc cattttgtaggtgaagaaatcgaggcttaagcaacttatctcccccagatcacacagctcatagagacacagataagact tggatacagatctggttattgccacagtttgtgaccttacctaagcaatttgatgcctattgagtcaccacttcctctgt gctcttgtatttgagtagctggagatatgtcctaagacttcccttaataaccccttaagcaccactcagctttaaatggt gccaaaagccttccagaacatctttttattttaagcctgaactcctatgggtgtgtgggtgggtgggcgggggtattcat atcttttctaggaaaacatccccctgggcatttgaggacttctcagctatgtattttagcgacttggagaaccaaatcca agccaaccatttctagggctgtttctccatagagccttggagaattcgcctcattgagggcagcatgaatccaaaacccc acattattttctcttttggttgacagagagtggaccaggagagaggcacgtggcctaacatgaccccttctccagaaatg ttcccattgacaccatcaggggcagacatgtttctggagctcgtgggggcacctcagtgccctggggctgtgcagtttga agttccttttcctttctcaggcatccagccctgcgtgtacagagctggagatgaacgtcatggactggttggcaaaaatg ctgggacttccagagcacttcttgcaccaccaccccagcagccagggcggaggcgtcctgcaggtacctcccttggcaaa gct cacctagcttgggggctaagtagcgaaagacaagccaaaccctaacctggcaattctcccgt ctccatggagttt cccccacattacccacaccgtcatcaccaacagcaccatcatcacagcttcacctctactcccacctcagcttctgcttc attcacatgtactgctacttcctttgaaagaaattaaagagccaacacatgatcacatttccagtatgacttgattcagg tttcttagtctataatctgacaattcctttttggtgtcccattttgtatctcacggtaaaaggggaaaggagaaggcaag gagaggacttctctttctctccctgctaggttcaggagatccccttgcagtgagagcaattaacagcataaactgattaa cggtatcctctgaccctatcttctggatacttgtcaaattatggttcttcaaatatttctttttttcaagagtagtgcca tggagtggagctttctgggtgcctcccatggaccacacacattgttaggtgcttttgcatctataaatccttgacgttca tgagggcttggttctaagacctttgagattcctcagattcttgaattctttttttaaataaaaatcgtggctggacatgg tgactcaccctgtaatctcagcacattgagaggctgagacagatggatcacttagcccaggagttcaaaccagcctgggc aacatggtgaaactgatctctccaaacaaacaaaattagctgggtgtggtggcatgtgcctgtagacccagctacttggg atgctgaggtaggaggattgcttgagcccagaagattgaggctgcagtgggctatgattgtgccactgccctccagcctg ggcgacagtgtaagaccttgtctcaaaaaataaaaaaattgccatgttgctctgagatgagaaccaggaagttcactagg tcctcttgctagctaagtgactccctctctcactgcagccttgcagcaagattaaaatctgaacctcggaagaaagacaa attgcagcatgttgtggacattttggattgtcagcaaatagttacaacttcagatatcatatttgggagaacatgctaaa tgtctgcggtacatgatcttgcttttcatctgattatctcaggaaccctgcaggtgaatagtaccattccccaatgtttt gagataagagcactgaagttcagagagattaaataatttgccctagcttacacagctgataagcagaagaacgaggattc aaactgatgcctgtctaaatccaaaccatgctttctcctgtatcgtcagccatgtgaacttgagttagtcccatcacctc tctgagcatcactctcctca cttagtgtgacaagaatcataattatctcaaagaggtgttgtgaggagcaagtagaatg ccagaaagtgttttgtaaactatgaattgcaatacagatggaaggtgttgttaccattattattatttttaaaaacaggg cctggttctgtctcccaggctggagtgcagtggagccatcatggctcactgcagcctccatctcctgggcccaagcaatc ctccaacctcagcctcccacgtagctgggactacaggtgtgcaccactacacctggctttttgttttttgttttttttgt agagacagggtctcactatgttgtccaggctggtctcaaactcctggactcaagggatcctcccaaagtgctgggattac aggtgcgagccactgcacccagctgattattattattattatgctacatacttctttacataaatagctttctttttatg gagtaactcccaggcacttaa atctgtgggatctggtccacaccactctccatgacagtgtctgccaggcatttttagc aggattctatcagctgtaggtcacttgaagatttcaagaagcaaagacatcaaagactgggtgaatgaatgataaggaac cataaagactcctgtgaagttcctgaggtggccccgaagatttccacaatcatggccagagcaaaatcctacccaaccct tgtttggataatctatactcccatcctgggaagcagttaaagggatgctctccatttcatagacagaaaagagtcttctg gaggggaaatgttagcccaaggtcacaagagctattgacaactaaatgggcccaagtcaccagcctctcacacaggccag gatcctctcttcctggggactcaaactccatatccatttgtgtaataagctgagagttcttcttttaaatatgttttaca tggggagcaaacacatccaggagggacagaacattctctttttggtttctgtggcctctgtaatagagaggctggtatta ggtgcaaacttattttagaaggcagaataggaatgaaagttggggagggacatgggcaccctgggcaggaggagctgtgt atttccttctgtgaatagctatgacacacacatacacaaacacatacacacacagagagagagagagagagagagagaga gagagagagagaaaaaactagaaagcctggggaaatttggcaagagaatacagaaaggctgccatgataatccttttccc ctgcagagcacggtcagtgaatccactttgattgccctgctggcagcaaggaagaacaaaatcctggaaatgaaaacgtc tgagcccgatgctgatgagtcctgcctaaatgcccgactcgtggcctatgcctctgaccaggtgagttgcccgacgcagg acagcccttcgggttggtgcttggcttctggaatcttggtccttgagcaatttttttctagacgtgagtacgctggggtt ctgagcagctcagacatgggagcttgtctccagcaactgtagggaagacaagcttccaatgatcatatttggttcccgag tcttaggcttcagcagtttctggggggtgatcattccaggatgactctttgctgacaggtttctgtggcccttctaggct cactcctctgtggaaaaggctggtttgatttcccttgtgaagatgaaatttctgcctgtggatgacaacttctcactccg aggggaagctcttcagaaggccatcgaggaagacaagcagcggggcttggtgcccgtctttgtaagtcaggatatatgcc taagcttagaatgatagaacttggatgtgaggaaggaattttggcagaattcaggtaagtaacatgctgcacacaaaagc agaaaggtcctcccatacagtattttacacatcatgaggtgctatccataggtgtgttatggaataaattttgtgggtca taaccagcattaaaaagaaatatagtataaaatattagagtgcacacatatagccagagtatgtattgttttatgaaact tttttttcaaatacacacgt tacatgtactagattgttatataaaatgtgtttcttacgagccatggtaaaacacagtc tgaaatatacactgttctggtgggatggatgggagtagatcacgtctgtggtgaaatctttctcaggccaaatgtgtcac acgagcccaccctcctgtgttaacttgccttaattttcccctaggtctgtgcaacactagggaccactggggtctgtgca tttgactgcctgtcagagctgggccccatctgtaagtatcttccctctgtggctaggaagacaaggaatacatttttaaa tgtctcctaaagcaaggacctgaaaccagctctatgggattattcttgttcctctttggtcaatgcagagacatgggaag aaccaccaaaggtcatgagggtctcttccagggatccctggacattgcctttcccagtggtgtgacaagagttagaggtg gcctaccttgcctcctgtcctaggaggcgacagtaggagagccttcggttttctcatcctcttacttgtatgttgaactt tacttaatgcaggctatatccaaaatacagtgtgaattaggctagaatagaaatgctttctattctaccttcagaaaagg aaaagggtagggtaggggaaatcatgggagagattaaaggcagagaggaaacccagatgggactgtttaatccccaagca agaaaccactaggaaagagagataccttccctctaacttttgtattcggtgcactgacattgctctctgtgctggtggga aattgatttctgtgccaggatgttctaggctgaggccaagagggtgctggccctttacccagtggaagaaaaaggcaagg gtgaggctttgtagactttcccattcggaggtaatgatgcctccttcagccccacttcttcaaactgactccacctgctc ccatctccacacccctccgtttctcatttagccaaagcacatcatccttgcagcccaccactcagcttggccaggtgcga gacatctttccccacttcatacctcccctccggccaggtgatgtttgcctcctcaggtgcccgtgaggggctgtggctcc acatcgatgctgcttatgcaggcactgccttcctgtgccccgagttccgggggtttctgaaggggattgagtatgccgac tccttcacctttaatccttccaagtggatgatggtgcattttgactgtactgggttctggtgagtgtagcagcccagctc cgagcacgcaggaacgccttgcctcctctggagagacctcagccactaatgcccatttggaaacccacagggtcaaggac aagtacaagctgcagcagaccttcagtgtgaatcccatctacctcaggcatgccaactcaggcgtggccaccgacttcat ggtgagtggccagggacgggcagcctggtgggctcgggtggccagtgggaactgtaggcgtctgaccccccaaaatctgt acggtggctcccttcagaaggcagcacactatgagctcatctcataatactgccaatgcataccttggtttctaattgtg cctaagtatatagaatgaaacccagaaaatggttaaaaaccctagaaaatgagaccagcctttgaggcagtgtgcacatt tcctgaatatttgtggcattttttaattcccagaaatgctcttcctaccacaggtggaccagttccttctgcctccatct cgggtcatcttttttgtttcttacccagcagcagggcagggtggagaatttccctggtggggaaagagctttcttgctga aatcgcttttgtttttttgtccctgacagaggcgctgtggggcagctctgtggtagtgatgggctgcaggacttgtgtga ggttctggaagcctccaagcattcctgacttteccaactgactgcgcctcaactctctaactcactctctctctcttttc ttttgttttctttctttctttctttctttttttttttctgagacagagtσtcgctctgtcaaccaggctggagagcagtg gcgcatcttggctcactgcaacctccgccttccaggttcaagcgattctcctgcctcagctttccaagtatctgggacta caggcgtgagccaccgcgcccagcaaacctcaactctcttgattccacatcctcagccagtattttgcctgagggaaacg agttcttaacaaattgactccgcagtttgaggatgagcccttcctttacttgtaggggagacagggatgtaaacgaatgt attacacataacctggccaacggaggcagcagagcagagtgggggcaagcttggtttggaattccattccagcagtggcc ctttgggaaactaactggacctctctgagccttgctttccttatctgtaaaatgagaatagtggcattgattcat gggt attgtgaagcttaaatgggaacacgtgtggatcacctagcaaaatagccgtgtggcaagtgctcaatatatggtaggcat agtatttctgaaagctcttctttgaagctgcagagatttgttaggacagtggttaggcatgtaggtgctaaagccagatg gcatgtgttggagtcctggctttctgtttactaacttgtgtgacctcgggcaagtgacttaaactctgtgtccagatttc ctcttgtgtcaaatgaggctgatgaccacagttctggcttcttaggcttgctgtgaggattatacaaattaatacactga agtgctgagagcagtgtctgacccctgtaagcatccttccttgtgaagagatggttttatcttatcttcttggacaactg aagtgtcttgcccttttagtcttaaaataatagcttcgtcatcacttgattatactggctattctcccttggaccagtcc acaccctctttagatatttgaagcttttggattagaattgcagcggtaagcctcacggcttactggtggtgacagaagac cctctagaggtaaagaaagaaagaaaaataatggttctttatctccactgctctttctggtaggttttcagagattttta atgaaaaattaaaaaaattccagaacagcccaagggtcagatatctttagggataactgtaggtttgcttcctgagtgtg aattgatgcccattctcctatgagtgtatttgggtcatcataactgaggagcattatattcacccttgcccttttgaatt tcatgttaccgtttaaattcatttaccacagtgcctcaggatcttcccggggttcattcctaggagtttggagattttac agtgctctctgtcttccagataactcataaaaatgttagagtaaactcttcccagccctgctctggggaaccttattatt tttacctctccacccagaaggcactgccttacacttacccttcccccacctttaatcctatggatttgattttcaagtcc atgaagaaactcctagaaaagtgaagttgctatctttttcatgatcctgagggtcctcagagctactctcacctgggccc aatgtctttcccacccaggtggctgcagctttgaacagaagctcagtcctgctctgagatgagccagaaacagggcagca tcccaggagagaagacttaggtgcttaacccctggggtcctggaatcacctaaaatcagggctagattctctgacagcgg agaagctccctgttttctgcctctcactggacagagagcaccagtggagggagcgttaccttagccttggcaagggagcc ctgcaaggaccttacaaggacacagaggaggctggagatgcctcaaggtaaagaagagccctgtcaggctttatacgtcc agattttttgatccaacagaaaatgttggctagaaccactctgctgagtcagcatggatcagttttggaatagtgacaag aaaaggagcaactgggaataaggaagattgtgaagaaatcaaaataaaatcacctctgcctatcctggtttatttgctgg taaaataaagtagctctctctatatatgaaataaattggctataactatctggaaaccagaaccttttgacagatgatcc ctatcatccgttcattattctcttggagtgtccattggacaagaggtggagttgacactttccttgttacagcaattttg ttccattttcaggttttgatgccttctgctggcacaaaagcccccaagctgctccccagcacaacagagttttgcttgga aatcaaaggcttagtagttttctgctggggaaacattgtccatcaacaaaggggtaacatcccaactgtgcctggctcag gaaactggggtgaagggtgaaggtgaggacatttgtgaggatttgataatcttgtgtatgggcagataaatacgcagtgg gacaaacatttatttttagtcaacagaaattgtggtagaaactttctgacgtttgagggagatgtcattaggaaaccacg tgactcattagaataactgtaaatgttttccaaatcctctgctctattttcagatctgagaaatcagtctgaaattgatt tggaaattttcagatgtatggtgactgcaaccttgaactttaagctctgttgaatttggccaccaggagcaaagagtcaa ttttcatctaacagcggcagaaatttgggtgctcatttgaaatctgacagctggagtgatggctctcagatcacaggaat ctcacaggaaaatgaacaaggcagtgtaaggttaaataggggtcatcttggctctagacagaaatgctactgtgatttgt agctcacattttaaaataatctaaatagccaacacctactgacaacttcttctgaggctcttggcgttctttgtcctcac accacttgcccgggaggtgcaattggttctttatgtcccggactgatgagccagtgaggtggcactacccaaggtcacac agctagtaagtggcacagctggaggcgaaacctaggtctgcagggctctagtgtctgtgctctaactaccatactttaca ttttgggaggaataaaaatagaactttattttctgctattcaaggaatatagattcatttagagtaaaaatgtatttccc ttatgttgagtttctgggccgggatgaaatgtttaaagcagcacttgaaagcaaagtgcccttctcattggttcagggta atggacttgacttccacttgtctggctctcagacaagtgactattggccaccttcatcagtgatttggtcacacgatggg gcaacccttggggagcttggcttactccttagcaacagctcccagagtcatggtgacatcgtccatccctggagggctgg gcaggcaacagataatgcccagaaatgcccgagggagtggggcacccttgtctctaaccttgggcactgtgttcctttgt ttctagcactggcagatccccctgagccgacggtttcgctctgttaaactctggttcgtgattcggtccttcggggtgaa gaatcttcaagcacatgtcagacatgtatgtagcatgctgctgtgggggctgagcctgtgttcctctgttttctcatggc gaggaaggctggtttctactttgcagatctgcctaggagacttgcggtgtgtggttcaggtgtctgggcctgttcctcag ctcctgggacttgattctctttgttaaccagaggagcgctgagcacaacatgccctgagggctgcctgatgcctgtcctc tgctgagtgtctcaccgttccccttgctgtcactgagcactggggagggttggccccagagtctggtttgcaggaaagag aaagagaaagtaaatcaaggggaagtgtgtgtggccagggtaggatcctatctgctttggaattacctcaatggtcacag ctggctgaatacttttagcactattatgattatgcctgaaataaagctcccctggccttggacaggtagacctaccaagt ctggaacaaacctccctgcatcaacaggcatttattgaaggcctattttgcttaatttatttctattcaattcaacaatt acaaggtattgtgctaagaaagggacacagaggtaaatgagacaggtgcagcctctctcccatgttcttcatggaagaag cgggacttaactaagaactctggccactggcattgttctcccacttctacaagagtccacatgcaagacaaagccattga taaaagtagtgggggaagctgaagacactgtcctttctgcctatgtgtgtctttgtccttccacctttcctctagggaat tccttcttggttaaacaaacacaaaccaaaatgaagtggtggaagcggtaactatgattttttttaacatttaaaaaaaa taattattatgcttacataataattacgtatatatttatggggtatgtgtgaggttttgatacaggcatacaatgtgcaa tgatcaaattagggtaactgggtatccaccactcaaccatttatcatttctttgtgttagaaacattctagttccattct ttaagttagtttgaaatgtacagcaaattatagttaactatagttgccttattgtgccgcctaacattagatctatttaa ttgtatttttgcgcccgttaactatcacctctttatcccccattccctgctacccttcccagcctctgccaaccatcatt ctactgtgcgtctccacgagctcagtttgcttactttttaactcccacgtttgagtgagaacatgtgaaatttgtccttc tgtgcctggcttattttgcttaacataatgttctccagtttcctatgactggttttaatgttggtaattttacctttgta atcaccactggttgtttaccaatgagcagctgccaccaacaatattgaggaactttaggcactttgtgctgtttctagaa atgcagactcaagactggagggttgtgggcggggaatggttggtggaggttacaagtaattaggaacatttttttgctta cagtttgggactggatattcaatgtgcagatcctgactaacctcccttagcacttctgtttgcaaatcaaacccctgaat tcctcctattagcaaccccattgcctaccatatgaggcccacactcctgggcctggctttcaaggacttgacgattagct cctaccttagcttgggcatttcatcgacccatccagacctcatgctcagtccatctctgcaccttcacccgtgtccttca cctgaactaccctctcctctccaaatgttgtgaatggattaaattctgcttccactagaagcttttctgcctattccatc tgttctggtttctgcttcattagcattcctgtgatcacctactcaaacacctttacaaaactgtgctcaaagttcttcca atgtcccacaatagaagaaatggaattaaaataaagttgtttgatatgatttgattttatctcttcaacttgacggtgat gataat attgacacttgcgtaatgccttcaatacaaaaataaattctagttet ea tagatccttagcacagtgcctg gggtggtcactctaacctggcaaggctcagagggagtaattgccctgcttgagggaagaaggcccgggactttccctgaa gcctcccaattccaaatcctttcttcatagttctgggctgctttctactacactgagctcttggaaagttatataaaatt aaatttcatatttctgtgttacagagaagtgctttaaagaatggatttttagttctaccctttacctgtttgatgacctt agacaaattacttaacctttctatatttgtctgccttatttatttattgttatttatttttgagatgcaggtctctgctt gctcaggctgaagtgcggtagtgccatcagagctcactgcagccttgacctccccaggctcaggtgatcctcccacctca gcctcctgagtagctgggactacaggcgcataccatcatgcctggctactttttgtattttttgtagagatggggttttg tcatgttgcccaggttgttctcacgctcctgggctcaagcaatctgcctaccttggcctcccaaagtgcgaggattacag gcatgagccaccacccctggccatgccttcctaatttataaaaatgagaaaaggatactacctctctcaaattaaatgag ataatatatatgcagcccttagcacagggtctacctactact agttaagtactcaatgagtacctcttcctcttctctt cttccccttctteatcatctccttcttcatctaattataataaattgtcatcatcatcaccatcatcatcatcatcatcc tcatctcctatcacctacaatagggattggtaaacatttcctgtaaaaagccagatactaaatacttttggctttgtggg ccatactctattgtaattacctctgtactacaagagctaccgtagacaatatgtaaacaaatgggaatgctgtgttccaa aaaactttacaaacacaggtgggggctatatttggccatggctgcactgtgcctgcccttgacctagagcggtgcagggc actggcagcagctctgctttcatgacctgtaaagtggggctttggaggtggcagtgctgcctgtgctctgtattctcctc tcccctgacctctgcttctgttattgcaaacagcatgtgttgtaggagggataaaagcacagtgggaggagatctaccta ctgtcacttgtaccttgggaaagtcactttcccttggttccttctaaaaaatggaaagattgagctgggcacaggggcac gtgtctgtagtcccagctacttgggaggctgaggtgggaagctcaattgctcccaccatagcccaggtgggagttctggg ctatggtgtgctatgccaattgagtgtccgcactaagttcggcatcaatatggtgacctcccaggagcaaggga caeca ggttgcctaaggaggggtgaaggggcccaggttagaaatggagcaggtcaaaactcctgtgctgtttgaaactgaccacg caggggagaaaggggctctgagaaagatttggagaaactcatttcattatggtcaaaagacaggctcagggccagacatg gtggctcatgccagtaatcccagtactttgggaggcctaggaaggaggatcgcttaagcccaggagtttgataccagggt gaacaacctagtgagaccactgtctttacaaaaaaattaaaaaatgtagctgggcatggtggtgcatgtctgtagtccta gctactcaggaggtgaaggtgggaggattacttgagctcaggagttcaaggctgcagtgagctttgattgtgcaacatgc ctctgtactctagcctgtgtgacaaagcaagaccctatctctcaaaaaaaaaaaaaaaaaaaaaaaaaagaggttcagct aactcccttgccctctcttgaaatagagcagtaagtatgagaactaactgatagaattacttagcaaatatttttattga gatcttctggatgcttggagaaatttttaaaaagaaaagagaaggcaagtcctgtccttgtttagttagtaatcctgggt taaaaacaaaaagcaaaaaaccccaggacatttaaaaagatggtatgaacttcagtggaagattaatataatacaaagcc tttaacattttaaaatg aacaaaatattcataccatagaatgtaccattttactcatttttaagtgtacaattcagtgg cattaagaatactcacaatgtggtgtgaccatcaccattatttccagaattttttcatcatcccgagcagaaactctgta tccattaaccaggtccaaaacctttccatgatgggtggagacaagatgtgaaaatatgttctctatggaatgtcagaaac aggggatgaaaagggcatttggggtacagggtgagaagaggtttgagaggcaagtgaagcatgtaggcttaggatggggc agggccgccactagcccatatggcaacttgatgtgcactacaaacaggcatctcttcctttaggcacacgcagctcgcat gaggcacctggctgggaacgcagagcatggactgggttttggccctcacttgcccacttggccagtcaaggagctgtgaa atcaggagttgaggccgggttgcctggactgcaaagcacatgccttctgggttctggggctgagttgaaagagggccctg agatgagttctcgaggtggatcccatgtgacaggaaacagggcgccattggaaattttccagcttggaatatgagcaaaa tcaaatggagatgacaatgaggcagaagccgcttacaacggctgtgacgggaagatggccctggtttaaaaccatttagc agtctgaaagtttatgcatagtctcttgtctgatgattaatctcagttctctttatacttgcaattccagggtactgaaa tggctaaatattttgaatctctggtcagaaacgacccttcctttgaaattcctgccaagaggcaccttggcctggtggtt tttcgtctaaaggtaataccatcttccaagcccctctgtgaatgatgtcttgtggtgctccagagcctctcggaaacaca aactgggctctggggatgctgacagggggtgcgatggagacttcacttcctttatttttcaaacagggtcctaattgtct cacagaaaatgtgttaaaggaaatagctaaagctggccgtctcttcctcatcccggccactatccaggacaagttaatca tccgtttcactgtgacatcccagtttaccactagggatgacatcctgagagactggaatctcattcgagatgctgccact ctcatcctgagtcagcactgtacttcccaacccagccctcgggttgggaacctcatctcccaaatcaggggtgccagagc ctgggcctgtggaacgtcccttcagtctgtcagtggggcaggagatgatccagtccaggccaggaagatcatcaagcagc ctcagcgtgtgggagccggtcccatgaaaagggaaaatggcctccatcttgaaaccctgctggacccagttgatgactgc ttttcagaagaggccccagatgccaccaagcacaagctgtcctccttcctgttcagttacttgtctgtgcagactaagaa gaagacggtgcgctccctcagttgcaacagtgtgccagtgagtgctcagaagccactgcccacagaggcctctgtgaaga atgggggctcctccagggtcagaatcttttccaggtttccagaagacatgatgatgctgaagaaaagtgccttcaaaaaa ctcatcaaattctacagcgtccccagctttcctgaatgcagctctcaatgtggactccagctgccctgttgccctctgca ggccatggtttagacacagggccttcagccagagtctgaggatatacttcagggactctgtgaacccctcacaattgtat gccaactttgtgtgcttatgtgtacatgcatttttcttggggcgagttcataattttaatcaaattctcataggggcttc atgacccacaataggatacaaacgaagagtttaagccagcatgatccagatgggttcagcagtctggtcagtgagaaagg gccgagggtagacaggcagcttctgtggttcagcttgtgacatgatatataacacagaaataaattatgcttgtccctga aacaaaacataccctgtgtcacttaattggctgctgaaacattgattaaccagtctgggagcttaaacatatgt ctttt tttgaagcatcaattatgagtcaggcactgtggctcatggttcataaatgaggaaaccaacgtttaggtcacacagcttt aaataggcaaacccaggtctcctgcttccagtgaagcccaggctgtttccaccatgcagtactgctcaaggttggacctg aacaggagctcacagcccagcaggctgctggtcctccagtacatttaaatgtttcctttctaggtttggaacttgtgcat tttccccttattttcctggacccggtagtcaaataaaagctatgctcacaagtggcttgcccataattagttcagaggcc aaacacataattttatttccatttcagatggtactttgataggttgtgactctgaaatgggttatgtaaagagtattaaa gacaaacaaagctgggcattagttagaactttaaggatagatgttaaacagtaatatact tcacaatagggaaaagggt cccatgtgaactgaactcaacttggatttgtgcaaaggtgactaggcatttcacagcgtgaatgggagaatagggagaag gccagcctagacttagaagagtcaggaatgtgaaaaattacaaaaagcggaaagtggttgatgtgaaacccctctgggtt tgctaactggtgctttttgaagtaagactcttaccctcccacagagactgggagtcagggccctgtgttcaggggttcgc tggaacaaacagttaattctttcggcagctttgagttttcttaagcaggcactttaaggtgagctaggatcaacttaggg atgtggccttgagctgtgagaaactgtgttagtgtttgttcaagtctttataggcaaaggttgaggcctagttgagaagg gggctcggaggagcttagctagagtttggtcgagaaaagaatctttgttaagagtttaaagctttttttttttttttttt ttttttttttttgagactagtgctttctctctttcccaggctggagtgcagaggcacaatcatgtcttactgcagcctca acttcctgggcttgagcaatcctcctgcttcagcctcccaagtagctatttatttttgagatggggtctcattctgtgag tgcagtggttggaacacagttcactgcagcctcagcctctgaggctcaagctgtctttccacctcagtcccacgagtagc tgggactatgagtgcacaccactatgcctggctaatttttataactttttacagagacagggtctccctgtgttgcccag gctggtctggaactcctgggctcaggtgatc (SEQ ID Nθ:1224₃) cgactaagaagccctgttgacagctgccttccagcctcctctgtctgtctgccaggaggagcaatccaagggagatgatg gagccctgtgaataccgtgaataccgtgaatactaccgagctagagggaaagagatggtggattacatctcccagtacct gagcactgtgcgggagaggcaggtgactccaaatgtgcagcctggatacctgcgagcccagctacctgcgagtgctcccg aggaacccgacagctgggacagcatctttggggacattgaacgagtcatcatgcctggggtggttcactggcagagcccc cacatgcacgcctactatcctgctcttacctcatggccatccctgctaggagacatgctggccgatgccattaactgctt aggattcacgtgggcatctagcccagcttgcacagagctggagatgaacatcatggactggctggcgaagatgctggggc tcccggagtacttcctgcaccaccatcccagcagccgagggggaggtgtcttacagagcactgtcagcgaatccacttta attgccctgctggcagcaagaaagaacaaaatcctagcaatgacagcgtgcgagcccgatgctaacgagtcctccctgaa cgctcgtctcgttgcctacacctctgatcaggctcactcttcagtggagaaggctggcttgatttcccttgtgaagatca gatttctacctgtggacgacaacttctcactccgaggagaagctctccagaaagctattgaggaagacaagcaacagggc ttggtgcctgtgtttgtctgtgcaacgttagggactactggagtctgtgcatttgacaggctgtcagaactggggcccat ctgtgccagtgagggactgtggctccacgtcgatgctgcttatgcaggcacggcctttctgtgccctgagctccgagggt tcctggagggcatcgagtacgccgactccttcacctttaacccttccaagtggatgatggtacactttgactgtactgga ttctgggtcaaggacaagtacaagctgcagcagacctttagtgtgaaccccatctacctccgacatgccaactctggtgc agccacggacttcatgcattggcagatccccttgagccggcgctttcgctccattaagctgtggtttgtgattcggtcct tcggggtgaagaatcttcaagcacatgtcagacacggcacagaaatggctaaatactttgaatctctggtcagaagcgac ccttccttcgaaattcctgctaagaggcaccttggtttggtggttttccgtctgaagggtcctaattgtctcacagaaag tgtgttaaaggaaatagccaaagctggccagctctttctcatcccggctactatccaagacaagctgatcatccgtttca ctgtgacgtcccagtttaccaccaaggaggacatcctgagagattggcacctcatccaagaggctgctaaccttgtcctg agccagcactgcacttcccagccgagccctcgggccaagaacgtcatcccgccaccgccaggg-accagagggctatccct ggagtcagtcagcgagggaggagatgacccagcacaggcccggaagatcatcaagcagccaggagccagtctggcgagaa gggaaggcggctctgatctggaaacgatgccggatccctttgatgattgcttctctgaagaggcccccaacaccaccaag cacaagctgtcatcctttctgttcagttacttgtcggtccagaacaggaggaagacaacgcggtccctcagctgcaacag tgtgcctatgagtgcccagaagtcactccccgcagacgcttcactgaagaatgggggctccttccgggccagaatctttt ccgggttcccagaacaaatgatgatgatgaagaaaggtgccttcaaaaagctgatcaagttctacagcgtccccagcttt cctgaatgcagttctcagtgtgctcgccagctaccgtgctgccccctggaggccatggtgtagagtcctcaatcagaatg caagggtgcctgtgcttcagggagttggggaaccctcgaaattgcctgcagtttgtgtgcttattatgtgtgtgtgcatc ttgagggaagcaagcccattattttgatcataacctcacagggtcttcgtgatccacaacagattgtaactgggaagttt aagcgggcatgctccagaggttgcaggcgcttgtgtgatagaaggggctgagacggtggcatgctgttaagcttgtaatg tgaaaaacaacttagaaataaattgtgcttatatctaaaaaaaaaaaaaaa (SEQ ID NO: 12244) cttccacctcctgcgtgtccatctgtgagaaggagccagagcccaagggagatgatggagcctgaggagtacagagagag agggagagagatggtggattacatctgccagtacctgagcactgtgcgggagagacgtgtgacgccagacgtgcagcctg gctacctgcgagcccagctgcctgagagtgctcctgaggaccccgacagctgggacagcatctttggggacattgaacga atcatcatgcctggggtggtacattggcagagcccccatatgcacgcctactacccagccctcacctcttggccctccct gctaggagacatgctggctgatgccatcaactgcttgggattcacctgggcatccagccctgcgtgtacagagctggaga tgaacgtcatggactggttggcaaaaatgctgggacttccagagcacttcttgcaccaccaccccagcagccagggcgga ggcgtcctgcagagcacggtcagtgaatccactttgattgccctgctggcagcaaggaagaacaaaatcctggaaatgaa aacgtctgagcccgatgctgatgagtcctgcctaaatgcccgactcgtggcctatgcctctgaccaggctcactcctctg tggaaaaggctggtttgatttcccttgtgaagatgaaatttctgcctgtggatgacaacttctcactccgaggggaagct cttcagaaggccatcgaggaagacaagcagcggggcttggtgcccgtctttgtctgtgcaacactagggaccactggggt ctgtgcatttgactgcctgtcagagctgggccccatctgtgcccgtgaggggctgtggctccacatcgatgctgcttatg caggcactgccttcctgtgccccgagttccgggggtttctgaaggggattgagtatgccgactccttcacctttaatcct tccaagtggatgatggtgcattttgactgtactgggttctgggtcaaggacaagtacaagctgcagcagaccttcagtgt gaatcccatctacctcaggcatgccaactcaggcgtggccaccgacttcatgcactggcagatccccctgagccgacggt ttcgctctgttaaactctggttcgtgattcggtccttcggggtgaagaatcttcaagcacatgtcagacatggtactgaa atggctaaatattttgaatctctggtcagaaacgacccttcctttgaaattcctgccaagaggcaccttggcctggtggt ttttcgtctaaagggtcctaattgtctcacagaaaatgtgttaaaggaaatagctaaagctggccgtctcttcctcatcc cggccactatccaggacaagttaatcatccgtttcactgtgacatcccagtttaccactagggatgacatcctgagagac tggaatctcattcgagatgctgccactctcatcctgagtcagcactgtacttcccaacccagccctcgggttgggaacct catctcccaaatcaggggtgccagagcctgggcctgtggaacgtcccttcagtctgtcagtggggcaggagatgatccag tccaggccaggaagatcatcaagcagcctcagcgtgtgggagccggtcccatgaaaagggaaaatggcctccatcttgaa accctgctggacccagttgatgactgcttttcagaagaggccccagatgccaccaagcacaagctgtcctccttcctgtt cagttacttgtctgtgcagactaagaagaagacggtgcgctccctcagttgcaacagtgtgccagtgagtgctcagaagc cactgcccacagaggcctctgtgaagaatgggggctcctccagggtcagaatcttttccaggtttccagaagacatgatg atgctgaagaaaagtgccttcaaaaaactcatcaaattctacagcgtccccagctttcctgaatgcagctctcaatgtgg actccagctgccctgttgccctctgcaggccatggtttagacacagggccttcagccagagtctgaggatatacttcagg gactctgtgaacccctcacaattgtatgccaactttgtgtgcttatgtgtacatgcatttttcttggggcgagttcataa ttttaatcaaattc cataggggttcatgacccacaataggatacaaacgaagagtttaagccagcatgatccagatggg ttcagcagtctggtcagtgagaaagggccgagggtagacaggcagcttctgtggttcagcttgtgacatgatatataaca cagaaataaattatgcttgtccctgaaacaaaaaa (SEQ ID NO: 12245) agtgcgcaggactggcaagagggaagccgggctgctccacgcctttcacgccttccacctcctgcgtgtccatctgtgag aaggagccagagcccaagggagatgatggagcctgaggagtacagagagagagggagagagatggtggattacatctgcc agtacctgagcactgtgcgggagagacgtgtgacgccagacgtgcagcctggctacctgcgagcccagctgcctgagagt gctcctgaggaccccgacagctgggacagcatctttggggacattgaacgaatcatcatgcctggggtggtacattggca gagcccccatatgcacgcctactacccagccctcacctcttggccctccctgctaggagacatgctggctgatgcca ca actgcttgggattcacctgggcatccagccctgcgtgtacagagctggagatgaacgtcatggactggttggcaaaaatg ctgggacttccagagcacttcttgcaccaccaccccagcagccagggcggaggcgtcctgcagcagacggtcagtgaatc cactttgattgccctgctggcagcaaggaagaacaaaatcctggaaatgaaaacgtctgagcccgatgctgatgagtcct gcctaaatgcccgactcgtggcctatgcctctgaccaggctcactcctctgtggaaaaggctggtttgatttcccttgtg aagatgaaatttctgcctgtggatgacaacttctcactccgaggggaagctcttcagaaggccatcgaggaagacaagca gcggggcttggtgcccgtctttgtctgtgcaacactagggaccactggggtctgtgcatttgactgcctgtcagagctgg gccccatctgtgcccgtgaggggctgtggctccacatcgatgctgcttatgcaggcactgccttcctgtgccccgagttc cgggggtttctgaaggggattgagtatgccgactccttcacctttaatccttccaagtggatgatggtgcattttgactg tactgggttctgggtcaaggacaagtacaagctgcagcagaccttcagtgtgaatcccatctacctcaggcatgccaact caggcgtggccaccgacttcatgcactggcagatccccctgagccgacggtttcgctctgttaaactctggttcgtgatt cggtccttcggggtgaagaatcttcaagcacatgtcagacatggtactgaaatggctaaatattttgaatctctggtcag aaacgacccttcctttgaaattcctgccaagaggcaccttggcctggtggtttttcgtctaaagggtcctaattgtctca cagaaaatgtgttaaaggaaatagctaaagctggccgtctcttcctcatcccggccactatccaggacaagttaatcatc cgtttcactgtgacatcccagtttaccactagggatgacatcctgagagactggaatctcattcgagatgctgccactct catcctgagtcagcactgtacttcccaacccagccctcgggttgggaacctcatctcccaaatcaggggtgccagagcct gggcctgtggaacgtcccttcagtctgtcagtggggcaggagatgatccagtccaggccaggaagatcatcaagcagcct cagcgtgtgggagccggtcccatgaaaagggaaaatggcctccatcttgaaaccctgctggacccagttgatgactgctt ttcagaagaggccccagatgccaccaagcacaagctgtcctccttcctgttcagttacttgtctgtgcagactaagaaga agacggtgcgctccctcagttgcaacagtgtgccagtgagtgctcagaagccactgcccacagaggcctctgtgaagaat gggggctcctccagggtcagaatcttttccaggtttccagaagacatgatgatgctgaagaaaagtgccttcaaaaaact catcaaattctacagcgtccccagctttcctgaatgcagctctcaatgtggactccagctgccctgttgccctctgcagg ccatggtttagacacagggccttcagcagagtctgaggatatacttcagggactctgtgaacccctcacaattgtatgcc aactttgtgtgcttatgtgtacatgcatttttcttggggcgagttcataattttaatcaaattctcataggggctcatga cccacaataggatacaaacgaagagtttaagccagcatgatccagatgggttcatcagtctggtcagtgagaaagggccg agggtagacaggcagcttctgtggttcagcttgtgacatgatatataacacagaaataaattatgcttgtccctga (SEQ ID NO: 12246) gtaagtatcttccctctgtggctaggaagacaaggaatacatttttaaatgtctcctaaagcaaggacctgaaaccagct ctatgggattattcttgttcctctttggtcaatgcagagacatgggaagaaccaccaaaggtcatgagggtctcttccag ggatccctggacattgcctttcccagtggtgtgacaagagttagaggtggcctaccttgcctcctgtcctaggaggcgac agtaggagagccttcggttttctcatcctcttacttgtatgttgaactttacttaatgcaggctatatccaaaatacagt gtgaattaggctagaatagaaatgctttctattctaccttcagaaaaggaaaagggtagggtaggggaaatcatgggaga gattaaaggcagagaggaaacccagatgggactgtttaatccccaagcaagaaaccactaggaaagagagataccttccc tctaacttttgtattcggtgcactgacattgctctctgtgctggtgggaaattgatttctgtgccaggatgttctaggct gaggccaagagggtgctggccctttacccagtggaagaaaaaggcaagggtgaggctttgtagactttcccattcggagg taatgatgcctccttcagccccacttcttcaaactgactccacctgctcccatctccacacccctccgtttctcatttag ccaaagcacatcatccttgcagcccaccactcagcttggccaggtgcgagacatctttccccacttcatacctcccctcc ggccaggtgatgtttgcctcctcaggatcacctgaagtcaggagttcgagaccagcctgaccaacatggagaaaccccgt ctctactaaaaatacaaaattagttgggcatggtcgtgcatgcctgtaatcccagctactcaggaggctgaggcaggagt atcacttgaacccaggagacggaggttgcggtgagccaagaacatgccattgcactccagccttggcaacaagagcaaaa ctccgtctcaaagaaaaaaaaaatttttttttgtcaacccatgtgggtatgaaattgtttctcattatttgcatttcact aattactagtgaggtcaaacattttttccctcatttcttatccattaaagtttattctgtgaattgccagttcatggcca ttttgggggtgtagtttttcttactgatttattgaagtttaatgtttttctggaaactaatattttgctagttgtgtgaa ttgtaaatatcttctcccactgtatttttttaaaaactttttattgtctgaattagcacatatttagtgaatgcctctat gtgcaattctttttttttttttttttttttttttgagatggagtttcgctcttgtttcccagactggagtgcagtggcat gatctaagctcactgcaaccttcacctcccgggttcaagtgattctcctgcctcaggcctcctgagtagctgggattaca ggtgcccgctaccatgaccagctaattttttgtatttttagtagagacggggtttcatcatgttggccaggttggtctcg aactcctgacctcaggtgatccacccgcctcggccttccaaagtgtagggattacaggcatgagccagtgagctcagcct ctatgtgcaattcttaatgtcaagctgagggagaagtctaagaagttttatataagtctgacacccagggtgcctgtaat taaaggtggaatgaaattttaatttgcgagttgatccttctgttttttagttcagtacttcctcctttttagaatgtatg ctttccagataattagtgagataaagatttgattttcacttttagcatttctaaaagctgtaatatgctacctaacttgt ttttaattcttgctctaacttctgatattttatagttgtgtattttgaattatattttaaaggattaagtggattattgc acatgatatttagtaaagtgtttgggagcatttagcacagcctccaaaaattagaattccactagccccctgatcctaca atctggcatcttaagagtcaataatagcaaagttgagagaggcagcttggtgtggtggaaagaacatgggtattggatc cgatagccttaggttcaaatcctggcttcttcagtaattatcttctgtaattttagccaagtgtttaatttccttgagac tcagtttctcgaagatgaagtagaaaatggctttcaccaggttgttgtaaagactgaatcaaatagtgtgcatgaaaatt gcaaggcatagtgctcaggacatagttaacattcttaaatatatgttgaggaatggtgtgcacctgaaaattcctataaa agctgcaaatatacatgccttttgatccagctgttccacttcaggatatccttactcatgtgtgcaaagcaattttttgt agaaatgtttgtaatagcaaaagactggaaacaactgaaatgtacactgctagggaactgattactctctggtatgtcca cgcaatgcagctctatgaaaaaaaggagtacgtgtcaagatatattaacaaataaagtacagaatattgtactgtactta tcccttttgtgtttaacaaaagaaagaaaaggagaaaaattagaatatagtatatatttgcctttatgtgcaaaaaaagg aaatcactttttgttttttttgagacagggtctcattctgtcacccaggctggggtgcagtggcgctatcacggctcact gcaacctcaacctcccaggctcaagcgatcctcccgccacagcctcccaagtagctgggactacaggcacacgcgccatg cccagctaatttatttatttatttttggtagagatggggtttcgcgatgttacccaggctggtctcaaactcctgagttc aggtgatccacctgtcttggcctcccaaagtgctctgggattacaggcatgagccactgtgcctgacctcttttcttctt gatgtgaaattcttcatagattagacaaatttgcccattgtgcaaatatgttgcaaatatattttctcagtttgtcattt atcttgatttttcttatggttttaaaaaaatgtgattggatttatggtttctggcattgaaccatagttataaatgtatt ctttactctgaggttgtccagggaatcttctaattttcttaatttaattttcatcttttaaaaacagctctattgatgca taattga atacaaaaatagcatatatttactactatttgatgagtttggacatgtgtacacacccatgaagccatcagt taacctgatggtggtgatggtttcctgtaattttatgcttccatttttcacatttagatctgacttttctggaatttatc taagtgcacgatgtgaaagatagatacagcttatttttctttccagatggctataccttgttctaggacaatttattaaa tagtccatctttttctttctgatctgagatgctatctttattatatgctaaatttctgtacatgtttaaatttatttgct ccttttgtttgtctctttgtacaccagtatctacctcattgttctaattattcgagcttcaggatacattttaatacttc tgggtaggaacagaaccttctcgttactcttacaaaattttcttctttattctggtttatttttcctaagaactttaaaa gttggcactgaattccaaaatagaacacccaaaaacctgttgatttttccactgggattatgttaaattttcgggttaac ttaggggaaaaccattatttcatgatgttaaatcttactccatgagagagcatggtacgtcttttcatctgtacaggtct ttttttatattgttcagtagcaatttaaaaaaatcatccactatgttcaatgaaataaaaggccagatttaaaaatttgg caaggagttgaaaactataaaaaggaaccaaataaaaattctttttttgcccccataaggcagaagaaatacaaattcta caactgaaaaaatataatatctgatattaagaaatcaataaatggtttattatattagctacatttgaagagacaactaa aaaagaaaaatattttcaaaccaactcagaaacaagaagatggaaaataaagaatacaatgctatttatatttatatata atagtatatataatacacaagtttaacataggactgcatttgcagaatagaagagagataatggggagatagcaacactt ggagaaaaaataacgaacacttttttatttaaagtgcctaacttggctgggtgtggtggctgacacctgtaatcccaaca ctttgggaggctgagatgggtggatcatttgagcccaggagttcaagaccaacttgggtaacatggcgaaaccccatctc tacagaaaaactccaagaaataaaaaacaataa catctgagtgtggtagcacatgcctgcgtccttgctactcaggagg tgggggtggcagaattaccagggcctggaagtcaaggctgcaatgagctgtgatcgcatcactatacttcagcctggttg acgagtgagaccctgtctcaacaaataaaaataaaaataaaaataaaaatgcctaacttggtgcttggcactttctaaaa ttgacacataatatttgtacctgtttatggagtatatgtgatattttgatacatgcatacaatgtgtgtaatgatcaaat caggatatttaagatatccatcatctcaaacatttttctttgtgttcagaacattccaaatctagctattttgaaatata caataaattattaactatag catcctaatgtgctattgaatattattgaattccatctaattatatgtttgtaccaatt aaccaatctctacttattcctcacccccagctcccaccaaccctttccagtctctggtaactatcattttattctctacc tccatgagatcaaattttttacctcccatatcgttgtcaatattattatttttcccaccctggctcctaatgaaggattt attgacaatatcactggaatctaaatcctctaggccattttttcaccaatgcccttattttcttagggcttttttttttc ttaaatcaacagttttaatgagatataattcccattctataaaatttcctcgtttgaagtgtacagtttaatagctttta gtatatccacagaagtgtgcaaccatcaccataataaattttaaaacattttcagcagggcgcagtggctcacgcctgta atcccagctactcaggaggctgaggcaggagaattgcttgaacccaggaggcagaggtttcagtgagccgagattgcacc actgcaatccagcctgggccacagagtgagactccatctcaaaacaaaacaaaacaaagcaaaataaaacaaagcaaaat aaaacaaaaccaaaacccaacaattttgaacattttcatcttaccaccctgccaaaaatccctgttctccttagccatca atcttcagctccctacccacttctaaccatgaatctattttgtagatttgtctattctcgatatttcatatgaatgaaat aatataatatatggttccttgtgactagtttctttcacttagtatgtttccaagttca ccatgttttggtatgtatcag tacttcattcctttttatcatggaataatattctgttgtattgatatactacgtttcattcattcatctgaacatttgga ttatttccatttttgtctattataataattctgctatgaacacccatgtatacgtttttgtgtggacatgatttcatttt ccttggatatacacctagcagtagaattgttgagtcataaagaactctaggtttagctttctggggagcttccagattat tttccaaaatggctgtgccattttacattcccaccagtaaagtatgagggttctaatttttccctgtcttcaccaatact tgttgttatctatcttttttattatagtcatcatagtctgtatgaagtgatttctcactgtagttttttcagtagtaatt aaaaaatttcctacctattttagcctaaaattactttcctgactctcttcaaggagcctgccagagaattctctctctcg tgctgtctcccttatgcctgggcataagctctgataatgccctgtctgggaaaactcttttggccttctcaatttctatt acattgagagcccaagaacccatggtcagtaacaggccaatgagaagcctcctgcattagtctaggtgaaggataatggt ggcttggaccggaatagggtggtagtcatggaaatggggagaatttgacagactagatttattttggaaatagaactgaa tctgaacagattgaattgggcagggagcagggaaagtgaaggggaaggaagacaccaggtttatgccttcagcatttggg tggatgaatggatggatgaaaggatagatggatgcatggatggtggttggatggatgagtggttggatgaatggacggtc aaggggtgaatagatgggtggatggaaaatggagagatgatgaactgagatggggaagactagaagtggggcatattttt ggggaaagacagttttgcaatacgttaagtttgaggtgcctcagagtcataagagaggatttgtcagaaaggcagttgga tataagattttgaagctcaaaagacagggagggcctgatggtatgtttaaacctatacggatatcacataggtaacattt caagcctaagaaatgggccgggcgcagtggctcacacctgtaatcccagcactttggaaggctgaggcgggtggatcact tgaggtcaggagttcgagacaaacccagccaacatggtgaaaccccatctctgctaaaaacacaaaaattagtggggcat ggtggcacatacctgtaggcccagctactcaggaggttgaggtgggagaattgcttgaacccgggaggcagaggttgcag tgagccaagattgcgccactgcactccagcctgggcgacagagcaagactccgtctaaacaaaacaaaacaaaaaaagcc ttagaaatgggcaatgccaccaaagcagaaagatgaaaggagggcaatgccctgaggtgtgccagcattggaggaaacaa acagccagagatgtaggaggaaagcccagagaaactgtgagctgcaaggatgaagtagtaacaaataaaatgccaccaag agaaccagaaggacgactggaaacaaataaacaagaaagactattgcatttagcaacgtgaaaacgttggattacttttt actcagaaatcaaaccccaaggatagtgtttcccctccctacggggtttctgcaggtccctttacacgcccccttctact tctttaagtgctaaaagtgattaatttggggtgatgttttaatttctattctttttggcttataactgtgttttttcatt ctttgcaacaacagatagtatgttgtaatagaaaaatccattgtggtcaatgataacttctgcctgttcctgggcacagg gggcatcactattagtgcctgttcctccctccctactgctgataaggaaacaggggcaggaataatactaataatttgtg ctactttttctgcatacccttggccttattctggtctactgagctgggagcttgtctgaggctggagctctattgtctga atccaggggcagaaagaactgagggctcttttacggcatccacctggaggctgcctgcaggcttgggttgctaagtgcac tgcttaatttagaagcgccttttatcctggctctcttgaccagtcaaagttgtggtcgctgttttctacaaggactgggg aaagaaagggtggaattaattaaacctggaggaagggactttgaagggcggagctaaggtcaaagaaagaaccctttaaa taaagggcccacactggctgccagggagtgcgcaggactggcaagagggaagccgggctgctccacgcctttcacgcctt ccacctcctgcgtgtccatctgtgagaaggagccagagcccaagggagatgatggagcctgaggagtacagagagagagg tgagcaacgggcatccctggccctcttccctgctgctactcctgcaggaacggctgctggtgggtggcccttagattgtg gggtgacatttgatgggagcattagaattgccttctgagagttggcaccagcaacatttttttttctgcgaaaggaatgt gggatcagagtgtaaaacttttctcaaccactctttcattctccctctcatatacccactctcacatatgtccacactac cgtgccttgcttttcctccccactttcccacaaaattgaggatttggatccctgagccactagatgggaaaaggggattg ttcatattctgaaatagaaaaaaattttctcaatattctgtaatcactgcaaatcctttctttcttaacattcattcctt catgtgtgaatctatcagcagtgttctttcatttagtcattcatttcataaatatttagtaggtgcctactctgtatcag gcaaaaccaagtggttatccagttctcaggcatggatctcccttagcaggaaagtaggtagttgcttaaaaaagaatctt gaatgtctatttctataatgttttatatcctcctactcactaattagtgtgcgttagcttattccattgctttcctaagg cactgtcagctgagagcaagttcctgtggatatttatcttctgagtggaacacaaatacatttagcactgttcctggatc agtggagggttaggtctagagctctcagatctctggtggggccctgctggagaagaaccaggatgtgagagggttgaagg ggagcagaaggaagatagaatggtgtggaaatctacctttgtctcataagttttgtctggggttggttctgttcttaaga actttgcataagctgatgcagaggggagaaactgagtcccctctcctaggtaaaagcagcccagggagtac aaggaatg gatgttgagacagacaaagagatatgtacacacacacacatgcacacacagcaacagaggcactgaagactgcaatctga aagaataaataatttgcaatagtttcagagtgttcaacttgacttttttttccttccttactcatatgttcattcacttg atacatttttttttagcatctaaaaaatatcctaagcactgaggtgttgatggaggcagcaggagggagagaaagtcatt aagatttggtgccacatttcccaggccagggcagggggcttggtctggatccatggttgtgctttagggattctgtgagc ctcagaaattatacacaaagttctgtgtatatgtaagcctacagttttaatcagattcttgaattaagtcctcatatgag tccaaaaaagatgaataataactgattcaatggggatggtgaaaaaatagatttttttgtcctttatcggaactgggcat ggaatctttctatctgtgctaacagatataactggtgggtgtgtgtgtaacaatttttggatacaaagagctatagagtt tc attgaacctataaaatagttaatagatgttctgtttctgagaaggaaagaaaggtaggagagacaatcaaaattgaa gtggataaaggaaggggaaagaaaatgaaacgtttcactttggcgctagagttttgtgctttggagattttcctttttgt tcatttgctcacttagaaactccctccatcattcattcactccctcactctttttttaaattctgaagataaggtcgtgc aggggatcagatcctaccctcggcccatgaatctgtctctctcttttttttgagtccaggctggagtgcagtggcacgat ctcggctcactgcaacctccgtctcccaggttcaagcgattctcctgcctcagcctcccaagtagctgggattacatgcg cctgccaccacgcccggctaattttttgtatttttagtagagaggggtttgaccatgttagtcaggatggtcttgatctc ctgacctcgtgatccgcctgcctcagcctcccaaagtgctgggattacaggcatgagccactgtgcccggccaaatccat ctccttctttaccaagtctcttggcccggacctgagagggatgggcacaaatcggtcaggcccagtcaggggatttcagc ctgatttctctatgtcacttctagggagagagatggtggattacatctgccagtacctgagcactgtgcgggagagacgt gtgacgccagacgtgcagcctggctacctgcgagcccagctgcctgagagtgctcctgaggaccccgacagctgggacag catctttggggacattgaacgaatcatcatgcctggggtgagacacagtgaccacaagggcagttctggatttcagggca cagaagggtgggtggtggcctggagaaagacctgctttgggtcagcttgggatgagaatgcatccttcagccacttggcc accaacaccccagcccatctgctaggcatgtggagggcaggactttgactggtattaggtttctttttctttttttttgc ccagttgtgccatggcatgaggtttctgatgccagggcagggctggccagaacacctgcattccagagcacagcctggca gaagtgtggaagtctaatgggatgggtggagaagtgaacattttgtctgaggggaa&ggacactgtgtatagtaagacag gggagaggaagctggtggtagtgcctggccctgacgacggagccagagactcttctgtacagtgtctgagaccacaccaa agagaaggaaggaagtggggaacacatcctggcaaggacacgctggtgaccaggttgcgttggcccaggaaactgagtgg gccctggcaacccctcctgtcccctctgaggtctggtgattgagctgcttttcaagagcaagaagggactttccctgaat cattgatactttccatgatggagggtgcagcctgggatagtgctggtggggccaggaagctgatggaagctggctgatgc atgggcttgagctggagcctgccttgatgggtggtggacacccctgaccactggcggtgaggagctctgccatggtgctc atgctaaagtggcatcgactcccttcctgtggcggggctccctgccatgtgccagctctgtgctggccacatgacatgct atctaatttaatcttcccagtggccctgttttacagatgaggaaactgctgatgctcagagaagttaactgtcttgccca aagtcacagaattagtacctggtagatccaggattttaccctagaccagtcttacttcacaggctgtgccgtttctccta ccccctgtcacctctactggtgggtgcctgaatgtgcctggctaagcctgggcccctagcattgcctgtctggctccaca cccccacacaagctgtgtcttccctctccctgcttggggcatttgtgttctgaaccacacatgtttagaggctcttcctg aggccagcttgaggtttgccttca cattcccaaagaacttttgacttcaatgtgacaaaaaggccaggcgcgggggctc acacctgtaatcccagcactttgggaggccaaggcaggtggatcacctgaggtcgggagttcaagaccagcctgaccaac atggagaaaccccgtctctactaaaaatacaaaattagctgggcatggtggcacatgcctgtaatcccagctacttggga ggctgaggtaggagaatcgcttgaacccgggaggcggaggttgcggtgagctgagatagcgccgttgcactccagcctgg gcaacaagagcgaaactccatctcaaaaaaaaaaaaaagtgacaaaaatatgcctagaggcaggggtgggaaaatattca aactcagaaagtgatggcaattttgacttttttttttttttttttttgaagcaatagagacaaggtcttgctatgttgcc caagctggtctccaactcctgggctcaagtgatcctcctgcctcggccttccaaagtgttgggatgagaggcctaagcca ctacgcctggccatgagggcaatttcatacaaagccactcatctctttgaccattcagcctatttcacaagcattttttg aaaatgtcaatatcagtaaggctttacggaggctagatcctgataagattatctcctggattttattctgtaaaatgtaa tctgctgaggggctaactgtaatctgggagtgagactgaaagcaactgtcagaagaggtggaaatgagctgattcatttg atcaagaggaattccagcagttgctgtgggtatggtcggtgaggctcatttctggaaagaggtctgtttgtttttgataa gggctcttctggctattttatcttatttatcttacaagaacagactattgtctcttgatagagctaggaggtagaagccc ttctctggggtttccaaaatactgtcactaaggacagtgataatgatggtcaaatctctcaactcatctctcaggccaca ccagcctctgagagctggcctgaaagcagttggccctttgcttactcattttgctcagtgcctcattgaaaactgaatta gtttttctcttcctgccaccacctagaaaataagagaagaagaaaaactctctttcccctttaattccaaccctggttag acaatcctcatttacttttcatgagagagagagagcatccccacgggaaaagtcaggacaccaccctgctcgggtgtctg ggcttctgcctcattgcggtcacctgtccctatggggtatgtgtgaccacagggatgtggcctctctctgtcagccccag ttctcgcctgcaaaacagagataatgtgtaggtcctaccccatagggtcctgtgagaagtaagtaagagaaggcttggag agcaggagatgtggttattaccgatcatgactcttacatggtgaaaattggaggaagaggtttgattctctgagtcaagt caggatatgtgatgtgtctgtcacccacatgattagtttaccgttaatgttagagcttaacatttcacacatttcttgcc cacgcctccacccacacaacaaccctaggagacaggatttattttacgatgagaaactgaggttgagggaggtgcaggag aggctcctggtcttatggggtctgtactgtaaacactttttgagacctccttttgaaaaacaaaaaagaaggaggccgga cacagtggtgcacgcctgtaatcccagcactttgggaggctgaggcgggtggatcatgaggtcaggagttcgagactagc ctggccaacatagtgaaacactttctctattaaaaatacaaaaaattagccaggcatggtggtgggcacctgtaatccca gct cttgggaggctgaggcaggagaatctcttgaacctgggagccaggggttgcactgagccaagatggcgctgctgca ctccagccctggtgacagtgcgagaatctgtctcaaaaaaaaaaaaaaaagaatgaatctcaaaagagacccacacaaat ggtatgttggagcttaagttcattagcttcatggtaaatctacacggtcacacagctggttagggactgaggtgggatgg gaacttgtgtccttggacttaattcttaggctccttatactatacacactgtccaggacaaggtccttgctcttgaagga ctctaagtatgtgtggacagtaaagaacaggatgatgccctaagatgttatcaaatgagtcctcagtagagtgaaacatc tagaattctagagttctatcgctcagggaagggatcgaagggagctgtgggagctgggggagagttcgaggaggaaatga atatttagtagctttctaagaactggcaggttttggaaggtcatgtctttatagagagtgcctttctatcaggggacaca gcattgctcaaagacataaatgcagaaaggaacagggcatgcttcagagcagtgagatgaggagagatgagataatccat gaggccgatgaaccaccagggctgcttctgagttctgatggggggcccttcctgcccactcagctcctccttacatccgg ttttgattgtgggctcagggcttagcctggaggtcggcctcccatacgcttggtctgggctctcctctctaccgtctcct ttcctcactacattcccaatgtgatgcttaaggacagctttgaacccattcacccagaccctctgagttgcatgctcagg gagctcagtgctccataaaacaaaaacaaaaggtgccttttgcaagaaactggatgaaacaagtagtctgcttttctgga gctcacagtctgcccttccttttttttttttgagacggagtcttgctctgtcgcccaggctggagtgcagtggagcgatc ttggctcactgcaagctcagcctcccgggttcacatcattctcctgcctcagcctcctgagtagctgggactacaggctt ctgccaccccgcctggctaatttttttggtatttttagtagagatggggtttcaccatgttagccaggatggtctcaatc tcttgatctcgtgatccacctgcctcggcctcccaaagtgctgggattataggcatgagccaccgcacccggcctgccct tccttttattgctgggcaggggcggcatgaggggtaagtactggggactaatgtgaataccacccagaatcccacaactg ggttactgtagtgattttccttttgcatatttccttctggactttgcatatatgaaaaggctccactgatgatctagcat aggacatgggccacattagtgacaagaacaccagtgaacaagtctgattttcatggagttatgtcacttatttctgctta aaagtgtcagcccatctctagagtgacacttcaccttgccagagatggtctctggagaaagaaagcctgctggaaatgcc tcctggtgccaactctgtgcatgctctgcctccaggtggtacattggcagagcccccatatgcacgcctactacccagcc ctcacctcttggccctccctgctaggagacatgctggctgatgccatcaactgcttgggattcacctgggtgagtagcaa cggctgtaactactcgcaatggggaacgtagcagggagtggtatcctagggcagacatattttgtcttggtttctgaata tggctccacaataaatattaatgagggctatattctttaagcttacgctttattttaattttctcatcacatcctttaac cctatggaatcacgagtattga cccattttgtaggtgaagaaatcgaggcttaagcaacttatctcccccagatcacac agctcatagagacacagataagacttggatacagatctggttattgccacagtttgtgaccttacctaagcaatttgatg cctattgagtcaccacttcctctgtgctcttgtatttgagtagctggagatatgtcctaagacttcccttaataacccct taagcaccactcagctttaaatggtgccaaaagccttccagaacatctttttattttaagcctgaactcctatgggtgtg tgggtgggtgggcgggggtattcatatcttttctaggaaaacatccccctgggcatttgaggacttctcagctatgtatt ttagcgacttggagaaccaaatccaagccaaccatttctagggctgtttctccatagagccttggagaattcgcctcatt gagggcagcatgaatccaaaaccccacattattttctcttttggttgacagagagtggaccaggagagaggcacgtggcc taacatgaccccttctccagaaatgttcccattgacaccatcaggggcagacatgtttctggagctcgtgggggcacctc agtgccctggggctgtgcagtttgaagttccttttcctttctcaggcatccagccctgcgtgtacagagctggagatgaa cgtcatggactggttggcaaaaatgctgggacttccagagcacttcttgcaccaccaccccagcagccagggcggaggcg tcctgcaggtacctcccttggcaaagcttcacctagcttgggggctaagtagcgaaagacaagccaaaccctaacctggc aattctcccgttctccatggagtttcccccacattacccacaccgtcatcaccaacagcaccatcatcacagcttcacct ctactcccacctcagcttctgct eattcacatgtactgctacttcctttgaaagaaattaaagagccaacacat atca catttccagtatgacttgattcaggtttcttagtctataatctgacaattcctttttggtgtcccattttgtatctcacg gtaaaaggggaaaggagaaggcaaggagaggacttctctttctctccctgctaggttcaggagatccccttgcagtgaga gcaattaacagcataaactgattaacggtatcctctgaccctatcttctggatacttgtcaaattatggttcttcaaata tttctttttttcaagagtagtgccatggagtggagctttctgggtgcctcccatggaccacacacattgttaggtgcttt tgcatctataaatccttgacgttcatgagggcttggttctaagacctttgagattcctcagattcttgaattcttttttt aaataaaaatcgtggctggacatggtgactcaccctgtaatctcagcacattgagaggctgagacagatggatcacttag cccaggagttcaaaccagcctgggcaacatggtgaaactgatctctccaaacaaacaaaattagctgggtgtggtggcat gtgcctgtagacccagctacttgggatgctgaggtaggaggattgcttgagcccagaagattgaggctgcagtgggctat gattgtgccactgccctccagcctgggcgacagtgtaagaccttgtctcaaaaaataaaaaaattgccatgttgctctga gatgagaaccaggaagttcactaggtcctcttgctagctaagtgactccctctctcactgcagccttgcagcaagattaa aatctgaacctcggaagaaagacaaattgcagcatgttgtggacattttggattgtcagcaaatagttacaacttcagat ^' a catatttgggagaacatgctaaatgtctgcggtacatgatcttgcttttcatctgattatctcaggaaccctgcaggt gaatagtaccattccccaatgttttgagataagagcactgaagttcagagagattaaataatttgccctagcttacacag ctgataagcagaagaacgaggattcaaactgatgcctgtctaaatccaaaccatgctttctcctgtatcgtcagccatgt gaacttgagttagtcccatcacctctctgagcatcactctcctcatcttagtgtgacaagaatcataattatctcaaaga ggtgttgtgaggagcaagtagaatgccagaaagtgttttgtaaactatgaattgcaatacagatggaaggtgttgttacc attattattatttttaaaaacagggcctggttctgtctcccaggctggagtgcagtggagccatcatggctcactgcagc ctccatctcctgggcccaagcaatcctccaacctcagcctcccacgtagctgggactacaggtgtgcaccactacacctg gctttttgttttttgttttttttgtagagacagggtctcactatgttgtccaggctggtctcaaactcctggactcaagg gatcctcccaaagtgctgggattacaggtgcgagccactgcacccagctgattattattattattatgctacatacttct ttacataaatagctttctttttatggagtaactcccaggcacttaatatctgtgggatctggtccacaccactctccatg acagtgtctgccaggcatttttagcaggattcta cagctgtaggtcacttgaagatttcaagaagcaaagacatcaaag actgggtgaatgaatgataaggaaccataaagactcctgtgaagttcctgaggtggccccgaagatttccacaatcatgg ccagagcaaaatcctacccaacccttgtttggataatct actcccatcctgggaagcagttaaagggatgctctccat ttcatagacagaaaagagtcttctggaggggaaatgttagcccaaggtcacaagagctattgacaactaaatgggcccaa gtcaccagcctctcacacaggccaggatcctctcttcctggggactcaaactccatatccatttgtgtaataagctgaga gttcttcttttaaatatgttttacatggggagcaaacacatccaggagggacagaacattctctttttggtttctgtggc ctctgtaatagagaggctggtattaggtgcaaacttattttagaaggcagaataggaatgaaagttggggagggacatgg gcaccctgggcaggaggagctgtgtatttccttctgtgaatagctatgacacacacatacacaaacacatacacacacag agagagagagagagagagagagagagagagagagagaaaaaactagaaagcctggggaaatttggcaagagaatacagaa aggctgccatgataatccttttcccctgcagagcacggtcagtgaatccactttgattgccctgctggcagcaaggaaga acaaaatcctggaaatgaaaacgtctgagcccgatgctgatgagtcctgcctaaatgcccgactcgtggcctatgcctct gaccaggtgagttgcccgacgcaggacagcccttcgggttggtgcttggcttctggaatcttggtccttgagcaattttt ttctagacgtgagtacgctggggttctgagcagctcagacatgggagcttgtctccagcaactgtagggaagacaagctt ccaatgatcatatttggttcccgagtcttaggcttcagcagtttctggggggtgatcattccaggatgactctttgctga caggtttctgtggcccttctaggctcactcctctgtggaaaaggctggtttgatttcccttgtgaagatgaaatttctgc ctgtggatgacaacttctcactccgaggggaagctcttcagaaggccatcgaggaagacaagcagcggggcttggtgccc gtctttgtaagtcaggatatatgcctaagcttagaatgatagaacttggatgtgaggaaggaattttggcagaattcagg taagtaacatgctgcacacaaaagcagaaaggtcctcccatacagtattttacacatcatgaggtgctatccataggtgt gttatggaataaattttgtgggtcataaccagcattaaaaagaaatatagtataaaatattagagtgcacacatatagcc agagtatgtattgttttatgaaacttttttttcaaatacacacgtatacatgtactagattgttatataaaatgtgtttc ttacgagccatggtaaaacacagtctgaaatatacactgttctggtgggatggatgggagtagatcacgtctgtggtgaa a ctttctcaggccaaatgtgtcacacgagcccaccctcctgtgttaacttgccttaattttcccctaggtctgtgcaac actagggaccactggggtctgtgcatttgactgcctgtcagagctgggccccatctgtaagtatcttccctctgtggcta ggaagacaaggaatacatttttaaatgtctcctaaagcaaggacctgaaaccagctctatgggattattcttgttcctct ttggtcaatgcagagacatgggaagaaccaccaaaggtcatgagggtctcttccagggatccctggacattgcctttccc agtggtgtgacaagagttagaggtggcctaccttgcctcctgtcctaggaggcgacagtaggagagccttcggttttctc atcctcttacttgtatgttgaactttacttaatgcaggctatatccaaaatacagtgtgaattaggctagaatagaaatg ctttctattctaccttcagaaaaggaaaagggtagggtaggggaaatcatgggagagattaaaggcagagaggaaaccca gatgggactgtttaatccccaagcaagaaaccactaggaaagagagataccttccctctaacttttgtattcggtgcact gacattgctctctgtgctggtgggaaattgatttctgtgccaggatgttctaggctgaggccaagagggtgctggccctt tacccagtggaagaaaaaggcaagggtgaggctttgtagactttcccattcggaggtaatgatgcctccttcagccccac ttcttcaaactgactccacctgctcccatctccacacccctccgtttctcatttagccaaagcacatcatccttgcagcc caccactcagcttggccaggtgcgagacatctttccccacttcatacctcccctccggccaggtgatgtttgcctcctca ggtgcccgtgaggggctgtggctccacatcgatgctgcttatgcaggcactgccttcctgtgccccgagttccgggggtt tctgaaggggattgagtatgccgactccttcacctttaatccttccaagtggatgatggtgcattttgactgtactgggt tctggtgagtgtagcagcccagctccgagcacgcaggaacgccttgcctcctctggagagacctcagccactaatgccca tttggaaacccacagggtcaaggacaagtacaagctgcagcagaccttcagtgtgaatcccatctacctcaggcatgcca actcaggcgtggccaccgacttcatggtgagtggccagggacgggcagcctggtgggctcgggtggccagtgggaactgt aggcgtctgaccccccaaaatctgtacggtggctcccttcagaaggcagcacactatgagctcatctcataatactgcca atgcataccttggtttctaattgtgcctaagtatatagaatgaaacccagaaaatggttaaaaaccctagaaaatgagac cagcctttgaggcagtgtgcacatttcctgaatatttgtggcattttttaattcccagaaatgctcttcctaccacaggt ggaccagttccttctgcctccatctcgggtcatcttttttgtttcttacccagcagcagggcagggtggagaatttccct ggtggggaaagagctttcttgctgaaatcgcttttgtttttttgtccctgacagaggcgctgtggggcagctctgtggta gtgatgggctgcaggacttgtgtgaggttctggaagcctccaagcattcctgactttcccaactgactgcgcctcaactc tctaactcactctctctctcttttcttttgttttctttctttctttctttctttttttttttctgagacagagtctcgct ctgtcaaccaggctggagagcagtggcgcatcttggctcactgcaacctccgccttccaggttcaagcgattctcctgcc tcagctttccaagtatctgggactacaggcgtgagccaccgcgcccagcaaacctcaactctcttgattccacatcctca gccagtattttgcctgagggaaacgagttcttaacaaattgactccgcagtttgaggatgagcccttcctttacttgtag gggagacagggatgtaaacgaatg attacacataacctggccaacggaggcagcagagcagagtgggggcaagcttggt ttggaattccattccagcagtggccctttgggaaactaactggacctctctgagccttgctttccttatctgtaaaatga gaatagtggcattgattcatagggtattgtgaagcttaaatgggaacacgtgtggatcacctagcaaaatagccgtgtgg caagtgctcaatatatggtaggcatagtatttctgaaagctcttctttgaagctgcagagatttgttaggacagtggtta ggcatgtaggtgctaaagccagatggcatgtgttggagtcctggctttctgtttactaacttgtgtgacctcgggcaagt gacttaaactctgtgtccagatttcctcttgtgtcaaatgaggctgatgaccacagttctggcttcttaggcttgctgtg aggattatacaaattaatacactgaagtgctgagagcagtgtctgacccctgtaagcatccttccttgtgaagagatggt ttt tcttatcttcttggacaactgaagtgtcttgcccttttagtcttaaaataatagcttcgtcatcacttgattatac tggctattctcccttggaccagtccacaccctctttagatatttgaagcttttggattagaattgcagcggtaagcctca cggcttactggtggtgacagaagaccctctagaggtaaagaaagaaagaaaaataatggttctttatctccactgctctt tctggtaggttttcagagatttttaatgaaaaattaaaaaaattccagaacagcccaagggtcagatatctttagggata actgtaggtttgcttcctgagtgtgaattgatgcccattctcctatgagtgtatttgggtcatcataactgaggagcatt atattcacccttgcccttttgaatttcatgttaccgtttaaattcatttaccacagtgcctcaggatcttcccggggttc attcctaggagtttggagattttacagtgctctctgtcttccagataactcataaaaatgttagagtaaactcttcccag ccctgctctggggaaccttattatttttacctctccacccagaaggcactgccttacacttacccttcccccacctttaa tcctatggatttgattttcaagtccatgaagaaactcctagaaaagtgaagttgctatctttttcatgatcctgagggtc ctcagagctactctcacctgggcccaatgtctttcccacccaggtggctgcagctttgaacagaagctcagtcctgctct gagatgagccagaaacagggcagcatcccaggagagaagacttaggtgcttaacccctggggtcctggaatcacctaaaa tcagggctagattctctgacagcggagaagctccctgttttctgcctctcactggacagagagcaccagtggagggagcg ttaccttagccttggcaagggagccctgcaaggaccttacaaggacacagaggaggctggagatgcctcaaggtaaagaa gagccctgtcaggctttatacgtccagattttttgatccaacagaaaatgttggctagaaccactctgctgagtcagcat ggatcagttttggaatagtgacaagaaaaggagcaactgggaataaggaagattgtgaagaaatcaaaataaaatcacct ctgcctatcctggtttatttgctggtaaaataaagtagctctctctatatatgaaataaattggctataactatctggaa accagaaccttttgacagatgatccctatcatccgttcattattctcttggagtgtccattggacaagaggtggagttga cactttccttgttacagcaattttgttccattttcaggttttgatgccttctgctggcacaaaagcccccaagctgctcc ccagcacaacagagttttgcttggaaatcaaaggcttagtagttttctgctggggaaacattgtccatcaacaaaggggt aacatcccaactgtgcctggctcaggaaactggggtgaagggtgaaggtgaggacatttgtgaggatttgataatcttgt gtatgggcagataaatacgcagtgggacaaacatttatttttagtcaacagaaattgtggtagaaactttctgacgtttg agggagatgtcattaggaaaccacgtgactcattagaataactgtaaatgttttccaaatcctctgctctattttcagat ctgagaaatcagtctgaaattgatttggaaattttcagatgtatggtgactgcaaccttgaactttaagctctgttgaat ttggccaccaggagcaaagagtcaattttcatctaacagcggcagaaatttgggtgctcatttgaaatctgacagctgga gtgatggctctcagatcacaggaatctcacaggaaaatgaacaaggcagtgtaaggttaaataggggtcatcttggctct agacagaaatgctactgtgatttgtagctcacattttaaaataatctaaatagccaacacctactgacaacttcttctga ggctcttggcgttctttgtcctcacaccacttgcccgggaggtgcaattggttctttatgtcccggactgatgagccagt gaggtggcactacccaaggtcacacagctagtaagtggcacagctggaggcgaaacctaggtctgcagggctctagtgtc tgtgctctaactaccatactttacattttgggaggaataaaaatagaactttattttctgctattcaaggaatatagatt catttagagtaaaaatgtatttcccttatgttgagtttctgggccgggatgaaatgtttaaagcagcacttgaaagcaaa gtgcccttctcattggttcagggtaatggacttgacttccacttgtctggctctcagacaagtgactattggccaccttc a cagtgatttggtcacacgatggggcaacccttggggagcttggcttactccttagcaacagctcccagagtcatggtg acatcgtccatccctggagggctgggcaggcaacagataatgcccagaaatgcccgagggagtggggcacccttgtctct aaccttgggcactgtgttcctttgtttctagcactggcagatccccctgagccgacggtttcgctctgttaaactctggt tcgtgattcggtccttcggggtgaagaatcttcaagcacatgtcagacatgtatgtagcatgctgctgtgggggctgagc ctgtgttcctctgttttctcatggcgaggaaggctggtttctactttgcagatctgcctaggagacttgcggtgtgtggt tcaggtgtctgggcctgttcctcagctcctgggacttgattctctttgttaaccagaggagcgctgagcacaacatgccc tgagggctgcctgatgcctgtcctctgctgagtgtctcaccgttccccttgctgtcactgagcactggggagggttggcc ccagagtctggtttgcaggaaagagaaagagaaagtaaatcaaggggaagtgtgtgtggccagggtaggatcctatctgc tttggaattacctcaatggtcacagctggctgaatacttttagcactattatgattatgcctgaaataaagctcccctgg ccttggacaggtagacctaccaagtctggaacaaacctccctgcatcaacaggcatttattgaaggcctattttgcttaa tttatttctattcaattcaacaattacaaggtattgtgctaagaaagggacacagaggtaaatgagacaggtgcagcctc tctcccatgttcttcatggaagaagcgggacttaactaagaactctggccactggcattgttctcccacttctacaagag tccacatgcaagacaaagccattgataaaagtagtgggggaagctgaagacactgtcctttctgcctatgtgtgtctttg tccttccacctttcctctagggaattccttcttggttaaacaaacacaaaccaaaatgaagtggtggaagcggtaactat gattttttttaacatttaaaaaaaataattattatgcttacataataattacgtat tatttatggggtatgtgtgaggt tttgatacaggcatacaatgtgcaatgatcaaattagggtaactgggtatccaccactcaaccatttatcatttctttgt gttagaaacattctagttccattctttaagttagtttgaaatgtacagcaaattatagttaactatagttgccttattgt gccgcctaacattagatctatttaattgtatttttgcgcccgttaactatcacctctttatcccccattccctgctaccc ttcccagcctctgccaaccatcattctactgtgcgtctccacgagctcagtttgcttactttttaactcccacgtttgag tgagaacatgtgaaatttgtccttctgtgcctggcttattttgcttaacataatgttctccagtttcctatgactggttt taatgttggtaattttacctttgtaatcaccactggttgtttaccaatgagcagctgccaccaacaatattgaggaactt taggcactttgtgctgtttctagaaatgcagactcaagactggagggttgtgggcggggaatggttggtggaggttacaa gtaattaggaacatttttttgcttacagtttgggactggatattcaatgtgcagatcctgactaacctcccttagcactt ctgtttgcaaatcaaacccctgaattcctcctattagcaaccccattgcctaccatatgaggcccacactcctgggcctg gctttcaaggacttgacgattagctcctaccttagcttgggcatttcatcgacccatccagacctcatgctcagtccatc tctgcaccttcacccgtgtccttcacctgaactaccctctcctctccaaatgttgtgaatggattaaattctgcttccac tagaagcttttctgcctattccatctgttctggtttctgcttcattagcattcctgtgatcacctactcaaacaccttta caaaactgtgctcaaagttcttccaatgtcccacaatagaagaaatggaattaaaataaagttgtttgatatgatttgat tttatctcttcaacttgacggtgatgataattattgacacttgcgtaatgccttcaatacaaaaataaattctagttctt cattagatccttagcacagtgcctggggtggtcactctaacctggcaaggctcagagggagtaattgccctgcttgaggg aagaaggcccgggactttccctgaagcctcccaattccaaatcctttcttcatagttctgggctgctttctactacactg agctcttggaaagttatataaaattaaatttcatatttctgtgttacagagaagtgctttaaagaatggatttttagttc taccctttacctgtttgatgaccttagacaaattacttaacctttctatatttgtctgccttatttatttattgttattt atttttgagatgcaggtctctgcttgctcaggctgaagtgcggtagtgccatcagagctcactgcagccttgacctcccc aggctcaggtgatcctcccacctcagcctcctgagtagctgggactacaggcgcataccatcatgcctggctactttttg tattttttgtagagatggggttttgtcatgttgcccaggttgttctcacgctcctgggctcaagcaatctgcctaccttg gcctcccaaagtgcgaggattacaggcatgagccaccacccctggccatgccttcctaatttataaaaatgagaaaagga tactacctctctcaaattaaatgagataatatatatgcagcccttagcacagggtctacctactactcagttaagtactc aatgagtacctcttcctcttctcttcttccccttct catcatctccttcttcatctaattataataaattgtcatcatc atcacca catcatcatcatcatcctcatctcctatcacctacaatagggattggtaaacatttcctgtaaaaagccaga tactaaatacttttggctttgtgggccat c ctattgtaattacctctgtactacaagagctaccgtagacaatatgta aacaaatgggaatgctgtgttccaaaaaactttacaaacacaggtgggggctatatttggccatggctgcactgtgcctg cccttgacctagagcggtgcagggcactggcagcagctctgctttcatgacctgtaaagtggggctttggaggtggcagt gctgcctgtgctctgtattctcctctcccctgacctctgcttctgttattgcaaacagcatgtgttgtaggagggataaa agcacagtgggaggagatctacctactgtcacttgtaccttgggaaagtcactttcccttggttccttctaaaaaatgga aagattgagctgggcacaggggcacgtgtctgtagtcccagctacttgggaggctgaggtgggaagctcaattgctccca ccatagcccaggtgggagttctgggctatggtgtgctatgccaattgagtgtccgcactaagttcggcatcaatatggtg acctcccaggagcaagggatcaccaggttgcctaaggaggggtgaaggggcccaggttagaaatggagcaggtcaaaact cctgtgctgtttgaaactgaccacgcaggggagaaaggggctctgagaaagatttggagaaactcatttcattatggtca aaagacaggctcagggccagacatggtggctcatgccagtaatcccagtactttgggaggcctaggaaggaggatcgctt aagcccaggagtttgataccagggtgaacaacctagtgagaccactgtctttacaaaaaaattaaaaaatgtagctgggc atggtggtgcatgtctgtagtcctagctactcaggaggtgaaggtgggaggattacttgagctcaggagttcaaggctgc agtgagctttgattgtgcaacatgcctctgtactctagcctgtgtgacaaagcaagaccctatctctcaaaaaaaaaaaa aaaaaaaaaaaaaagaggttcagctaactσccttgccctctcttgaaatagagcagtaagtatgagaactaactgataga attacttagcaaatatttttattgagatcttctggatgcttggagaaatttttaaaaagaaaagagaaggcaagtcctgt ccttgtttagttagtaatcctgggttaaaaacaaaaagcaaaaaaccccaggacatttaaaaagatggtatgaacttcag tggaagattaatataatacaaagcctttaacattttaaaatgtaacaaaatattcataccatagaatgtaccattttact catttttaagtgtacaattcagtggcattaagaatactcacaatgtggtgtgaccatcaccattatttccagaatttttt catcatcccgagcagaaactctgtatccattaaccaggtccaaaacctttccatgatgggtggagacaagatgtgaaaat atgttctctatggaatgtcagaaacaggggatgaaaagggcatttggggtacagggtgagaagaggtttgagaggcaagt gaagcatgtaggcttaggatggggcagggccgccactagcccatatggcaacttgatgtgcactacaaacaggcatctct tcctttaggcacacgcagctcgcatgaggcacctggctgggaacgcagagcatggactgggttttggccctcacttgccc acttggccagtcaaggagctgtgaaatcaggagttgaggccgggttgcctggactgcaaagcacatgccttctgggttct ggggctgagttgaaagagggccctgagatgagttctcgaggtggatcccatgtgacaggaaacagggcgccattggaaat tttccagcttggaatatgagcaaaatcaaatggagatgacaatgaggcagaagccgcttacaacggctgtgacgggaaga tggccctggtttaaaaccatttagcagtctgaaagtttatgcatagtctcttgtctgatgattaatctcagttctcttta tacttgcaattccagggtactgaaatggctaaatattttgaatctctggtcagaaacgacccttcctttgaaattcctgc caagaggcaccttggcctggtggtttttcgtctaaaggtaataccatcttccaagcccctctgtgaatgatgtcttgtgg tgctccagagcctctcggaaacacaaactgggctctggggatgctgacagggggtgcgatggagacttcacttcctttat ttttcaaacagggtcctaattgtctcacagaaaatgtgttaaaggaaatagctaaagctggccgtctcttcctcatcccg gccactatccaggacaagttaatcatccgtttcactgtgacatcccagtttaccactagggatgacatcctgagagactg gaatctcattcgagatgctgccactctcatcctgagtcagcactgtacttcccaacccagccctcgggttgggaacctca tctcccaaatcaggggtgccagagcctgggcctgtggaacgtcccttcagtctgtcagtggggcaggagatgatccagtc caggccaggaagatcatcaagcagcctcagcgtgtgggagccggtcccatgaaaagggaaaatggcctccatcttgaaac cctgctggacccagttgatgactgcttttcagaagaggccccagatgccaccaagcacaagctgtcctccttcctgttca gttacttgtctgtgcagactaagaagaagacggtgcgctccctcagttgcaacagtgtgccagtgagtgctcagaagcca ctgcccacagaggcctctgtgaagaatgggggctcctccagggtcagaatcttttccaggtttccagaagacatgatgat gctgaagaaaagtgccttcaaaaaactcatcaaattctacagcgtccccagctttcctgaatgcagctctcaatgtggac tccagctgccctgttgccctctgcaggccatggtttagacacagggccttcagccagagtctgaggat tacttcaggga ctctgtgaacccctcacaattgtatgccaactttgtgtgcttatgtgtacatgcatttttcttggggcgagttcataatt ttaatcaaattctcataggggcttcatgacccacaataggatacaaacgaagagtttaagccagcatgatccagatgggt tcagcagtctggtcagtgagaaagggccgagggtagacaggcagcttctgtggttcagcttgtgacatgatatataacac agaaataaattatgcttgtccctgaaacaaaacataccctgtgtcacttaattggctgctgaaacattgattaaccagtc tgggagcttaaacatatgtactttttttgaagcatcaattatgagtcaggcactgtggctcatggttcataaatgaggaa accaacgtttaggtcacacagctttaaataggcaaacccaggtctcctgcttccagtgaagcccaggctgtttccaccat gcagtactgctcaaggttggacctgaacaggagctcacagcccagcaggctgctggtcctccagtacatttaaatgtttc ctttctaggtttggaacttgtgcattttccccttattttcctggacccggtagtcaaataaaagctatgctcacaagtgg cttgcccataattagttcagaggccaaacacataattttatttccatttcagatggtactttgataggttgtgactctga aatgggttatgtaaagagtattaaagacaaacaaagctgggcattagttagaactttaaggatagatgttaaacagtaat atactatcacaatagggaaaagggtcccatgtgaactgaactcaacttggatttgtgcaaaggtgactaggcatttcaca gcgtgaatgggagaatagggagaaggccagcctagacttagaagagtcaggaatgtgaaaaattacaaaaagcggaaagt ggttgatgtgaaacccctctgggtttgctaactggtgctttttgaagtaagactcttaccctcccacagagactgggagt cagggccctgtgttcaggggttcgctggaacaaacagttaattctttcggcagctttgagttttcttaagcaggcacttt aaggtgagctaggatcaacttagggatgtggccttgagctgtgagaaactgtgttagtgtttgttcaagtctttataggc aaaggttgaggcctagttgagaagggggctcggaggagcttagctagagtttggtcgagaaaagaatctttgttaagagt ttaaagcttttttttttttttttttttttttttttttgagactagtgctttctctctttcccaggctggagtgcagaggc acaatcatgtcttactgcagcctcaacttcctgggcttgagcaatcctcctgcttcagcctcccaagtagctatttattt ttgagatggggtctcattctgtgagtgcagtggttggaacacagttcactgcagcctcagcctctgaggctcaagctgtc tttccacctcagtcccacgagtagctgggactatgagtgcacaccactatgcctggctaatttttataactttttacaga gacagggtctccctgtgttgcccaggctggtctggaactcctgggctcaggtgatccgactaagaagccctgttgacagc tgccttccagcctcctctgtctgtctgccaggaggagcaatccaagggagatgatggagccctgtgaataccgtgaatac cgtgaatactaccgagctagagggaaagagatggtggattacatctcccagtacctgagcactgtgcgggagaggcaggt gactccaaatgtgcagcctggatacctgcgagcccagctacctgcgagtgctcccgaggaacccgacagctgggacagca tctttggggacattgaacgagtcatcatgcctggggtggttcactggcagagcccccacatgcacgcctactatcctgct cttacctcatggccatccctgctaggagacatgctggccgatgccattaactgcttaggattcacgtgggcatctagccc agcttgcacagagctggagatgaacatcatggactggctggcgaagatgctggggctcccggagtacttcctgcaccacc atcccagcagccgagggggaggtgtcttacagagcactgtcagcgaatccactttaattgccctgctggcagcaagaaag aacaaaatcctagcaatgacagcgtgcgagcccgatgctaacgagtcctccctgaacgctcgtctcgttgcctacacctc tgatcaggctcactcttcagtggagaaggctggcttgatttcccttgtgaagatcagatttctacctgtggacgacaact tctcactccgaggagaagctctccagaaagctattgaggaagacaagcaacagggcttggtgcctgtgtttgtctgtgca acgttagggactactggagtctgtgcatttgacaggctgtcagaactggggcccatctgtgccagtgagggactgtggct ccacgtcgatgctgcttatgcaggcacggcctttctgtgccctgagctccgagggttcctggagggcatcgagtacgccg ac ccttcacctttaacccttccaagtggatgatggtacactttgactgtactggattctgggtcaaggacaagtacaag ctgcagcagacctttagtgtgaaccccatctacctccgacatgccaactctggtgcagccacggacttcatgcattggca gatccccttgagccggcgctttcgctccattaagctgtggtttgtgattcggtccttcggggtgaagaatcttcaagcac atgtcagacacggcacagaaatggctaaatactttgaatctctggtcagaagcgacccttccttcgaaattcctgctaag aggcaccttggtttggtggttttccgtctgaagggtcctaattgtctcacagaaagtgtgttaaaggaaatagccaaagc tggccagctctttctcatcccggctactatccaagacaagctgatcatccgtttcactgtgacgtcccagtttaccacca aggaggacatcctgagagattggcacctcatccaagaggctgctaaccttgtcctgagccagcactgcacttcccagccg agccctcgggccaagaacgtcatcccgccaccgccagggaccagagggctatccctggagtcagtcagcgagggaggaga tgacccagcacaggcccggaagatcatcaagcagccaggagccagtctggcgagaagggaaggcggctctgatctggaaa cgatgccggatccctttgatgattgcttctctgaagaggcccccaacaccaccaagcacaagctg catcctttctgttc agttacttgtcggtccagaacaggaggaagacaacgcggtccctcagctgcaacagtgtgcctatgagtgcccagaagtc actccccgcagacgcttcactgaagaatgggggctccttccgggccagaatcttttccgggttcccagaacaaatgatga tgatgaagaaaggtgccttcaaaaagctgatcaagttctacagcgtccccagctttcctgaatgcagttctcagtgtgct cgccagctaccgtgctgccccctggaggccatggtgtagagtcctcaatcagaatgcaagggtgcctgtgcttcagggag ttggggaaccctcgaaattgcctgcagtttgtgtgcttattatgtgtgtgtgcatcttgagggaagcaagcccattattt tgatcataacctcacagggtcttcgtgatccacaacagattgtaactgggaagtttaagcgggcatgctccagaggttgc aggcgcttgtgtgatagaaggggctgagacggtggcatgctgttaagcttgtaatgtgaaaaacaacttagaaataaatt gtgcttatatctaaaaaaaaaaaaaaacttccacctcctgcgtgtccatctgtgagaaggagccagagcccaagggagat gatggagcctgaggagtacagagagagagggagagagatggtggattacatctgccagtacctgagcactgtgcgggaga gacgtgtgacgccagacgtgcagcctggctacctgcgagcccagctgcctgagagtgctcctgaggaccccgacagctgg gacagcatctttggggacattgaacgaatcatcatgcctggggtggtacattggcagagcccccatatgcacgcctacta cccagccctcacctcttggccctccctgctaggagacatgctggctgatgccatcaactgcttgggattcacctgggcat ccagccctgcgtgtacagagctggagatgaacgtcatggactggttggcaaaaatgctgggacttccagagcacttcttg caccaccaccccagcagccagggcggaggcgtcctgcagagcacggtcagtgaatccactttgattgccctgctggcagc aaggaagaacaaaatcctggaaatgaaaacgtctgagcccgatgctgatgagtcctgcctaaatgcccgactcgtggcct atgcctctgaccaggctcactcctctgtggaaaaggctggtttgatttcccttgtgaagatgaaatttctgcctgtggat gacaacttctcactccgaggggaagctcttcagaaggccatcgaggaagacaagcagcggggcttggtgcccgtctttgt ctgtgcaacactagggaccactggggtctgtgcatttgactgcctgtcagagctgggccccatctgtgcccgtgaggggc tgtggctccacatcgatgctgcttatgcaggcactgccttcctgtgccccgagttccgggggtttctgaaggggattgag tatgccgactccttcacctttaatccttccaagtggatgatggtgcattttgactgtactgggttctgggtcaaggacaa gtacaagctgcagcagaccttcagtgtgaatcccatctacctcaggcatgccaactcaggcgtggccaccgacttcatgc actggcagatccccctgagccgacggtttcgctctgttaaactctggttcgtgattcggtccttcggggtgaagaatctt caagcacatgtcagacatggtactgaaatggctaaatattttgaatctctggtcagaaacgacccttcctttgaaattcc tgccaagaggcaccttggcctggtggtttttcgtctaaagggtcctaattgtctcacagaaaatgtgttaaaggaaatag ctaaagctggccgtctcttcctca cccggccactatccaggacaagttaatcatccgtttcactgtgacatcccagttt accactagggatgacatcctgagagactggaatctcattcgagatgctgccactctcatcctgagtcagcactgtacttc ccaacccagccctcgggttgggaacctcatctcccaaatcaggggtgccagagcctgggcctgtggaacgtcccttcagt ctgtcagtggggcaggagatgatccagtccaggccaggaagatcatcaagcagcctcagcgtgtgggagccggtcccatg aaaagggaaaatggcctccatcttgaaaccctgctggacccagttgatgactgcttttcagaagaggccccagatgccac caagcacaagctgtcctccttcctgttcagttacttgtctgtgcagactaagaagaagacggtgcgctccctcagttgca acagtgtgccagtgagtgctcagaagccactgcccacagaggcctctgtgaagaatgggggctcctccagggtcagaatc ttttccaggtttccagaagacatgatgatgctgaagaaaagtgccttcaaaaaactca caaattctacagcgtccccag ctttcctgaatgcagctctcaatgtggactccagctgccctgttgccctctgcaggccatggtttagacacagggccttc agccagagtctgaggatatacttcagggactctgtgaacccctcacaattgtatgccaactttgtgtgcttatgtgtaca tgcatttttcttggggcgagttcataattttaatcaaattctcataggggttcatgacccacaataggatacaaacgaag agtttaagccagcatgatccagatgggttcagcagtctggtcagtgagaaagggccgagggtagacaggcagcttctgtg gttcagcttgtgacatgatatataacacagaaataaattatgcttgtccctgaaacaaaaaaagtgcgcaggactggcaa gagggaagccgggctgctccacgcctttcacgccttccacctcctgcgtgtccatctgtgagaaggagccagagcccaag ggagatgatggagcctgaggagtacagagagagagggagagagatggtggattacatctgccagtacctgagcactgtgc gggagagacgtgtgacgccagacgtgcagcctggctacctgcgagcccagctgcctgagagtgctcctgaggaccccgac agctgggacagcatctttggggacattgaacgaatcatcatgcctggggtggtacattggcagagcccccatatgcacgc ctactacccagccctcacctcttggccctccctgctaggagacatgctggctgatgccatcaactgcttgggattcacct gggcatccagccctgcgtgtacagagctggagatgaacgtcatggactggttggcaaaaatgctgggacttccagagcac ttcttgcaccaccaccccagcagccagggcggaggcgtcctgcagcagacggtcagtgaatccactttgattgccctgct ggcagcaaggaagaacaaaatcctggaaatgaaaacgtctgagcccgatgctgatgagtcctgcctaaatgcccgac cg tggcctatgcctctgaccaggctcactcctctgtggaaaaggctggtttgatttcccttgtgaagatgaaatttctgcct gtggatgacaacttctcactccgaggggaagctcttcagaaggccatcgaggaagacaagcagcggggcttggtgcccgt ctttgtctgtgcaacactagggaccactggggtctgtgcatttgactgcctgtcagagctgggccccatctgtgcccgtg aggggctgtggctccacatcgatgctgcttatgcaggcactgccttcctgtgccccgagttccgggggtttctgaagggg attgagtatgccgactccttcacctttaatccttccaagtggatgatggtgcattttgactgtactgggttctgggtcaa ggacaagtacaagctgcagcagaccttcagtgtgaatcccatctacctcaggcatgccaactcaggcgtggccaccgact tcatgcactggcagatccccctgagccgacggtttcgctctgttaaactctggttcgtgattcggtccttcggggtgaag aatcttcaagcacatgtcagacatggtactgaaatggctaaatattttgaatctctggtcagaaacgacccttcctttga aattcctgccaagaggcaccttggcctggtggtttttcgtctaaagggtcctaattgtctcacagaaaatgtgttaaagg aaatagctaaagctggccgtctcttcctcatcccggccactatccaggacaagttaatcatccgtttcactgtgacatcc cagtttaccactagggatgacatcctgagagactggaatctcattcgagatgctgccactctcatcctgagtcagcactg tacttcccaacccagccctcgggttgggaacc catctcccaaatcaggggtgccagagcctgggcctgtggaacgtccc- ttcagtctgtcagtggggcaggagatgatccagtccaggccaggaagatcatcaagcagcctcagcgtgtgggagccggt cccatgaaaagggaaaatggcctccatcttgaaaccctgctggacccagttgatgactgcttttcagaagaggccccaga tgccaccaagcacaagctgtcctccttcctgttcagttacttgtctgtgcagactaagaagaagacggtgcgctccctca gttgcaacagtgtgccagtgagtgctcagaagccactgcccacagaggcctctgtgaagaatgggggctcctccagggtc agaatcttttccaggtttccagaagacatgatgatgctgaagaaaagtgccttcaaaaaactcatcaaattctacagcgt ccccagctttcctgaatgcagctctcaatgtggactccagctgccctgttgccctctgcaggccatggtttagacacagg gccttcagcagagtctgaggatatacttcagggactctgtgaacccctcacaattgtatgccaactttgtgtgcttatgt gtacatgcatttttcttggggcgagttcataattttaatcaaattctcataggggctcatgacccacaataggatacaaa cgaagagtttaagccagcatgatccagatgggttcatcagtctggtcagtgagaaagggccgagggtagacaggcagctt ctgtggttcagcttgtgacatgatatataacacagaaataaattatgcttgtccctga (SEQ ID NO: 12247) gatccccagagactttccagatatctgaagaagtcctgatgtcactgccccggtccttccccaggtagagcaacactcct cgtcgcaacccaactggctccccttaccttctacacacacacacacacacacacacacacacacacacacacacacaaat ccaagacaacactactaaggcttctttgggagggggaagtagggataggtaagaggaaagtaagggacctcctatccagc ctccatggaatcctgacttcttttccttgttatttcaacttcttccaccccatcttttaaactttagactccagccacag aagcttacaactaaaagaaactctaaggccaatttaatccaaggtttcattctatgtgctggagatggtgtacagtaggg tgaggaaaccaaattctcagttggcactggtgtacccttgtacaggtgatgtaacatctctgtgcctcagtttgctcact ataaaatagagacggtaggggtcatggtgagcactacctgactagcatataagaagctttcagcaagtgcagactactct tacccacttcccccaagcacagttggggtgggggacagctgaagaggtggaaacatgtgcctgagaatcctaatgaaatc ggggtaaaggagcctggaacacatcctgtgaccccgcctgtcctgtaggaagccagtctctggaaagtaaaatggaaggg ctgcttgggaactttgaggatatttagcccaccccctcatttttacttggggaaactaaggcccagagacctaaggtgac tgcctaagttagcaaggagaagtcttgggtattcatcccaggttggggggacccaattatttctcaatcccattgtattc tggaatgggcaatttgtccacgtcactgtgacctaggaacacgcgaatgagaacccacagctgagggcctctgcgcacag aacagctgttctccccaggaaatcaactttttttaattgagaagctaaaaaattattctaagagaggtagcccatcctaa aaatagctgtaatgcagaagttcatgttcaaccaatcatttttgcttacgatgcaaaaattgaaaactaagtttattaga gaggttagagaaggaggagctctaagcagaaaaaatcctgtgccgggaaaccttgattgtggctttttaatgaatgaaga ggcctccctgagcttacaatataaaagggggacagagaggtgaaggtctacacatcaggggcttgctcttgcaaaaccaa accacaagacagacttgcaaaagaaggcatgcacagctcagcactgc (SEQ ID NO: 12248) aaaccacaagacagacttgcaaaagaaggcatgcacagctcagcactgctctgttgcctggtcctcctgactggggtgag ggccagcccaggccagggcacccagtctgagaacagctgcacccacttcccaggcaacctgcctaacatgcttcgagatc tccgagatgccttcagcagagtgaagactttctttcaaatgaaggatcagctggacaacttgttgttaaaggagtccttg ctggaggactttaagggttacctgggttgccaagccttgtctgagatgatccagttttacctggaggaggtgatgcccca agctgagaaccaagacccagacatcaaggcgcatgtgaactccctgggggagaacctgaagaccctcaggctgaggctac ggcgctgtcatcgatttcttccctgtgaaaacaagagcaaggccgtggagcaggtgaagaatgcctttaataagctccaa gagaaaggcatctacaaagccatgagtgagtttgacatcttcatcaactacatagaagcctacatgacaatgaagatacg aaactgagacatcagggtggcgactctatagactctaggacataaattagaggtctccaaaatcggatctggggctctgg gatagctgacccagccccttgagaaaccttattgtacctctctta agaatatttattacctctgatacctcaaccccca tttctatttatttactgagcttctctgtgaacgatttagaaagaagcccaatattataatttttttcaatatttattatt ttcacctgtttttaagctgtttccatagggtgacacactatggtatttgagtgttttaagataaattataagttacataa gggaggaaaaaaaatgttctttggggagccaacagaagcttccattccaagcctgaccacgctttctagctgttgagctg ttttccctgacctccctctaatttatcttgtctctgggcttggggcttcctaactgctacaaatactcttaggaagagaa accagggagcccctttgatgattaattcaccttccagtgtctcggagggattcccctaacctcattccccaaccacttca ttcttgaaagctgtggccagcttgttatttataacaacctaaatttggttctaggccgggcgcggtggctcacgcctgta atcccagcactttgggaggctgaggcgggtggatcacttgaggtcaggagttcctaaccagcctggtcaacatggtgaaa ccccgtctctactaaaaatacaaaaattagccgggcatggtggcgcgcacctgtaatcccagctacttgggaggctgagg caagagaattgcttgaacccaggagatggaagttgcagtgagctgatatcatgcccctgtactccagcctgggtgacaga gcaagactctgtctcaaaaaaataaaaataaaaataaatttggttctaatagaactcagttttaactagaatttattcaa ttcctctgggaatgttacattgtttgtctgtcttcatagcagattttaattttgaataaataaatgtatcttattcacat C (SEQ ID NO:12249) agatcttgtaaactgtagaatgcaccctccaaaatctatttgcataagcacacacacacacacacacacacacaccccag cagttcttgcctgcccagattcctctgcagctaaagtgatgaaacttactgggcggagcttcctaaaaagattattaggg tctcctgggttggtgtgcctttaaacctttggactttaccacctcctatctctcctatctccttgcaacaaaggttagga gaacaagaatgcagaaaaaacgggtcctggatgacatctgagtgcctgctttgggcttcttgatgagtgagacagaaaat aaaatacaaccccctcttttaaaagccatgcttactcaggttttccttcatttgcagctaaatacagaaatgagagaata ttttggagcagggatggaagaagagaggtattccccttcccacaaccttctgatttcccagtacatcccccactggaaaa attcatttaaaatcagtataataagcattgattagatgcctactatgcatctgggcttgagggcaaactggactcaggcc ttttggcctcaagaagctcacagtgtgagagtggcatttgtgtcctcttgaaattcacaggactaaattgtgcccaggct gacattctatccatccataggtgcctgccttctcacttccctctcttcat ggctcttgccttgtaccaaaatccaaacc caaatctcctcacatgtgagtgttggcattcatgtctcagacatgacctatgggcttgggacttttccccgtggacccca gtgacttttcagatgaacaggtatcttcaaaaacttgagaaataggagtcctgtttgttgttcttgttgctttgtcaata taaggcacagggtctttattcaaatgttcatactatctcttgacagaaatactatgagacatattgatggagaagccgtt atctccatatgctaaatgaggacttgcaccagggaacttgcccatggttctctccaaccacttaaattctgaaattttga atgagagtggacagtaatttcaaatcaatggggaaagaatcaaatcttcagcaaatggcttgagataattagctacacat ttcagaacaaataaagaagtcagatccgggccgggcacagtggctcatgcctgtaatctcagcactctgggaggccaagg cgggcggatcataaggtcaggagatcgagaccatcctggttaacacagtgaacccctctctaataaaaatacaaaaaaaa ataaaaaaacttagccgggcgtggtgccaggcgcctgtagtcccagctactcgggacgctgaggcaggagaatggcttga actcgggaggcagagcttgcaggtgagctgagatcatgccactgcactccagcctgggcaacagagcgagactctgtctc aaaaaaaaaaaagaagtcagatcctaacctcaaccctatttaacagattatagatgaaagaaaggtacaaatggctttta catacctcccttctccctgacattttgtatgtgtgtgtgtgtgtatttacacacacatctcatataaggaaattgaaggg aggctgcctgcatccctgagtcactctccctctccttctgaatgcttacctgtgcccagaccacctccttagcctcgcac cctccaggcttacagggcactcttctatgcccatcccaagtatagctgaaccttccaagggccagacttggtgctaagta ccaagtacgcaaagattaataaaacaatgtcctgtttcagggagctcaaagctgattcggcagggcatggtgtgtacatg aatgataaccacgtagggttgcaggtttcctagtgaggtaagcacaaggcaagatgggaaacaaaggaaggaggggttca cagcctcacccagagtccagaacccctggcctgcctggtgcccatgctgagtccacttctggaacacccagctcagagag ggggttagacctgcaggctaacacagacacagcccagaaaacccaggagccgagggggaaggagaaaggtgcaagaaggg gaaacccaggtcctggtccccttctctctgcttcctggcagcagaactcagacagaacccttaagccagtctaagtctgg caggaccagtaagttctgagttagctccatactagtttctagcaggctctttctcacttcctgattcttaggtttctaca ttgacactccctgaagagttgggaagagacaccacagtcccctgaccctgatccataggtcacacagcaggcatccacag ggtgggcgtgggccctctcatccctccctcccactcacttcacgctggctgggccccaaggtgtttgcaccccttgcagt gagtgaccttctctagtgcagcaagctcagaacctgctgccactggagttgtcccattgctgatgcagaaaggtgaagaa ctagcagaacactggaaatgccctccatctgggtccatggctacttaatgctccctggcaggcaggaggacaggtgc at tccctgttgggacagatgaaaaacagacacagggaggatgagtgatttgccctgactatagagtggcagggccaaggcag agcccaggcctcctgcacctaggtcagtgttcctcccagttacagtctaaactggaatgcaggcaaagcccctgtggaag gggaaggtgaaggctcaatcaaaggatccccagagactttccagatatctgaagaagtcctgatgtcactgccccggtcc ttccccaggtagagcaacactcctcgccgcaacccaactggctccccttaccttctacacacacacacacacacacacac acacacacacacacacacaaatccaagacaacactactaaggcttctttgggaaggggaagtagggataggtaagaggaa agtaagggacctcctatccagcctccatggaatcctgacttcttttccttgttatttcaacttcttccaccccatctttt aaactttagactccagccacagaagcttacaactaaaagaaactctaaggccaatttaatccaaggtttcattctatgtg ctggagatggtgtacagtagggtgaggaaaccaaa tctcagttggcactggtgtacccttgtacaggtgatgtaacatc tctgtgcctcagtttgctcactataaaatagagacggtaggggtcatggtgagcactacctgactagcatataagaagct ttcagcaagtgcagactactcttacccacttcccccaagcacagttggggtgggggacagctgaagaggtggaaacatgt ' gcctgagaatcctaatgaaatcggggtaaaggagcctggaacacatcctgtgaccccgcctgtcctgtaggaagccagtc tctggaaagtaaaatggaagggctgcttgggaactttgaggatatttagcccaccccctcatttttacttggggaaacta aggcccagagacctaaggtgactgcctaagttagcaaggagaagtcttgggtattcatcccaggttggggggacccaatt atttctcaatcccattgtattctggaatgggcaatttgtccacgtcactgtgacctaggaacacgcgaatgagaacccac agctgagggcctctgcgcacagaacagctgttctccccaggaaatcaactttttttaattgagaagctaaaaaattattc taagagaggtagcccatcctaaaaatagctgtaatgcagaagttcatgttcaaccaatcatttttgcttacgatgcaaaa attgaaaactaagtttattagagaggttagagaaggaggagctctaaggagaaaaaatcctgtgccgggaaaccttgatt gtggctttttaatgaatgaagaggcctccctgagcttacaatataaaagggggacagagaggtgaaggtctacacatcag gggcttgctcttgcaaaaccaaaccacaagacagacttgcaaaagaaggcatgcacagctcagcactgctctgttgcctg gtcctcctgactggggtgagggccagcccaggccagggcacccagtctgagaacagctgcacccacttcccaggcaacct gcctaacatgcttcgagatct (SEQ ID NO: 12250) ggggggggggatttagagacttgctcttgcactaccaaagccacaaagcagccttgcagaaaagagagctccatcatgcc tggctcagcactgctatgctgcctgctcttactgactggcatgaggatcagcaggggccagtacagccgggaagacaata actgcacccacttcccagtcggccagagccacatgctcctagagctgcggactgccttcagccaggtgaagactttcttt caaacaaaggaccagctggacaacatactgctaaccgactccttaatgcaggactttaagggttacttgggttgccaagc cttatcggaaatgatccagttttacctggtagaagtgatgccccaggcagagaagcatggcccagaaatcaaggagcatt tgaattccctgggtgagaagctgaagaccctcaggatgcggctgaggcgctgtcatcgatttctcccctgtgaaaataag agcaaggcagtggagcaggtgaagagtgattttaataagctccaagaccaaggtgtctacaaggccatgaatgaatttga catcttcatcaactgcatagaagcatacatgatgatcaaaatgaaaagctaaaacacctgcagtgtgtattgagtctgct ggactccaggacctagacagagctctctaaatctgatccagggatcttagctaacggaaacaactccttggaaaacctcg tttgtacctctctccgaaatatttattacctctgatacctcagttcccattctatttattcactgagcttctctgtgaac tatttagaaagaagcccaatattataattttacagtatttattatttttaacctgtgtttaagctgtttccattggggac actttatagtatttaaagggagattatattatatgatgggaggggttcttccttgggaagcaattgaagcttctattcta aggctggccacacttgagagctgcagggccctttgctatggtgtcctttcaattgctctcatccctgagttcagagctcc taagagagttgtgaagaaactcatgggtcttgggaagagaaaccagggagatcctttgatgatcattcctgcagcagctc agagggttcccctactgtcatcccccagccgcttcatccctgaaaactgtggccagtttgttatttataaccacctaaaa ttagttctaatagaactcatttttaactagaagtaatgcaattcctctgggaatggtgtattgtttgtctgcctttgtag cagcatctaattttgaataaatggatcttattcg (SEQ ID NO: 12251) cagtcaggagagagggcagtgagggtccatgctagctgggtcttgagcctcttctggggttcagtctctgatctacagca gtgtgtccacacctaaaacatcagctcagagaggcagttgcttctgctgttggaaacggacatcccaaaaaaaaacaaaa aacagaaatcaaaagggaaggagaaagtgaaagggatggaggcagcttgtccccttccctgtgcttgctgctggtagaaa actcagcctggaactgaccggagcagcagttcttgagtcaattccattccaacttctagaagattcttttcccgtcgaag agtgtcaggaggagaggccagacccccttgatcctgatctgccagccactgcatcagataagacgagataaccccgagtt cctgttctaccagccctggtgtggtaaccctctccaatggggcaggcttggaaccctgtgccaacgaagatcctcccccg tactgatgcaggaaggacagcccgggagtgtaccctctacatgggtctacttttatttaagcaaacattccctggtcaac aggacgtgtagcattgcccccccccttgggtcacacagaaaacaggtaccaggaggacaagtagttgcttgcccagggta cagaatgaaaggcaataggggactctaggcgaatgttcttcccacccaaactgaggtagtaggagaagtccctactgaag ggaaggtccagacataatcaaaggactaccagagatctcccaggtatctgtagaagtactaacatctccatccttcaaca gctacaggttacacgtctccaaggctgggacattgtaaaacagggccatggtaaggtctacccgacagcacagagcaagc ctcccagaagtctgagttccttctcctaacttctcatgctgggatctgagcttcttcgtgaaacacggggcagaggaggc accagaactctcctctgaccaactgccccacagcacacatatcctcaaaggatagtcttgaatacgtgatggaagaatta aagagagtgaggtctgaagaaaatcagccctctcggggtttcctttgggtaactgagtgctaaggtgacttccgagtcag caagaaatatcggacgttcaacccaggttgagtggaggaaacaattatttctcaatcctaatatgttctggaatagccca tttatccacgtcattatgacctgggagtgcgtgaatggaatccacagatgagggcctctgtacatagaacagctgtctgc ctcaggaaatacaacttttagtattgagaagctaaaaagaaaaaaaaattaaaagagaggtagcccatactaaaaatagc tgtaatgcagaagttcattccgaccagttctttagcgcttacaatgcaaaaaaaagggaaaggaaaaaaaaaaagaaaga aattaaactcaaaaattgcatggtttagaagagggaggaggagcctgaataacaaaaacctttgccaggaaggccccact gagccttcagtataaaagggggaccaagaacaggaggtctacatttagagacttgctcttgcactaccaaagccacaagg cagccttgcagaaaagagagctccatcatgcctggctcagcactgctatgctgcctgctcttactgactggcatgaggat cagcaggggccagtacagccgggaagacaataactgcacccacttcccagtcggccagagccacatgctcctagagctgc ggactgccttcagccaggtgaagactttctttgtaagtatgagctcgcctagcctttcttcctgccatcacctgaaatat gcattctgatggaactgcaaaaatagctctccttctcctcctccttctcctccttctctttctcctcctctgctttctcc tccttctcttcctcctccttctcttcttcctcctctccctcttcctcctccagctcttacctcatgctgctcctccccta tttccagcacctattacccttaaacttaaatctagagagtcctagggaaagccatgagttaaactaaacccaggcacatc cgaaaagctaactaggaggtgaatgcattgtctctcccatgctcaagaactttctgttaagtttccaataaggctccatg ttttgctggctaggacaaaagtctgtggtctctgcgtagtctctagatctgggggacagaggtttgggggtttgaagcag caccagcatagagagcttgcattacaaaagtattcccctttcagagctcctggaactgg atggaggtccaaagaaggca gagagctatgcaaaacaggctttctataagggactccagaaaggaagggttgacacaggtgctcttgaaacctgatctga ctcatctgaaagaagaccgggcctgggtctaacttctcccagtcagttaaattcagtcagaagtttttaaaaacaactgg atcccaagaggaaggactttgatttaactccgggctctagcactgtcaaatcctgttcttaaaactctcctttccacagt tgccagggcatttgaattgattacaaattcaaaactctacaaatggaaaagtattcaaatgacatgcacattgggtattt tccccagtccttgcattcacgttctttatgttcttccagcaaacaaaggaccagctggacaacatactgctaaccgactc cttaatgcaggactttaaggtaagagtccggtgggtgctggggagcgaccaagcgattagggacgggacgggaggtgctg cttgtgacagcagagctgggtctgatgccttgactttcaaaaagagaagtgagaagaccttgactcagcatatcgccagc agtcaagggttgtgaagagctcattctgtggtaaagggagaaaatgtaactagaaggggcggggatggggggggggtccc taggaacaggacagtccatcaaggttagcagcaacagatcaccattccagtaagtcacacccaacctctgatccctgcct ctagggttacttgggttgccaagcct atcggaaatgatccagttttacctggtagaagtgatgccccaggcagagaagc atggcccagaaatcaaggagcatttgaattccctgggtgagaagctgaagaccctcaggatgcggctgaggcgctgtgtg agtagcagatgcgttcttccccacccccaatccccttagagccacccaacaaatactgtctcctacagcccagtcaggcc acatgcatccagagacacacacagactagacaggagactaggtaaatctagagagacgcctgtccggtgtcgggtctctt gctcatctgtctctgagcgagtgtgggagtgactttgaggcactcacacgtgaagatttgcgcatagccttcctgttatt tgtgagtcattgtgggttattagctactcccctctctctccatgggaaggctggggcttcagtcatggctccctcacctc tgggctgccagctgaggctcccaagcacaggaaaacattcatctctttatctcatcttttgggaagcaaattcagtggca cagagctgggctgacaggacgctggtgtttcagaagggccagaagactgctatccctaagccagtatctatgaataatac agtcggggcatctatgtctctgaagcgatgccttggctgctcttgtttttcttacttc ctcactgatactgggacatca gctggagtctacttgtgcaacggttctggcctgacgatttggccccagtagctgagactttcgctcctctctcagacacc tagaaatagttcatggtggttgagattggagatagacaagaagagacactaaaaacagaacaggtgccttggagctctga gagacaaaacccgagacctgagttcacacccacacttagcaagccatcttagtgattgcaaagacatacattgcatcttt ctaggctgtcctctgctgtccccctcagtccctaccgaaatagataaggaccaatcacggctcagttctccctgggagct aagaagtgggcattgaagatgagcaagggtgtctccttcctcacacaacaagatagtttcccccaagtaccatggatgca gaattcaagcaagaattaccaatgctctcttttttcttcttcagcatcgatttctcccctgtgaaaataagagcaaggca gtggagcaggtgaagagtgattttaataaggtaagtggcaaagggggcgagtgtaacaagacctctgtctactcaccaaa gcgcagaaggagggcgggagctattctgcacctggagtgtgggaacccagcaaatggtgtgacctcctctgccagttaga aagccaccacctcagttacatttgttttctgcaaagcgtctctggcagtttctaaatgactgctccacttttgcaggctt ttggcttagactgaccagacagcctatgagcacagggcactaggtgttgaggagagtgacataggaaacagaaagtacag aaagtaccttgttgggaaacaggctgaacccacaagtacagaaagcagacatgaattaatttactcaggtacatcattgg ggctcagcctggatgcccctcccccaaatcagaacgagcagaaagcagaattcttacttgtcccggggcactttccacct ggcaaacaaaatgaggtttcacacttccaactgcctgtgaacctattcaaccctagttcccagaagccatgtggcctaca tcatcatctttgtgggctaggcagagacacctggcagggctctaacattagtgggcatgaattccatgacagcaggtcag agctgcagggtgaggactgcctacacactcaaaacataaaaaaaaaaaaaaaaaaacaccaaccatttccctgctatctc tatcactgccctgcttacaaactgctccctctggcatctttgcataacattctgcataagcattatatgagcactggcct cttaaaaaaaattagttgaaaaggtgccaccctgaagacagtgctttggggactgaatgcttcccttgctgactcctggc agtgcttaaagctgggagaaggttggtcccaccacatcctgactactacagtatagttgtctctcttctttcatttccct gtccccatttctttattgtacataaagtaactggtgtatgtgcacacacatagtgctctctctttcttttccttttttaa actaaatggccgatgttctgttctggttggcatcagatggagatggtctgggggaaagtactgggtttgtgaaaataccc ccttctccattagtggcatgctctttcagctcttatctttatattccagtaagttattttgctctcattgttttaacaaa agaacccaacaacaccaaatctttgcataccttgttcgattggagaattttaatgtttttcatttatcattgtaaaaccg aggacaattttataacttttttgtacgtggctgttacatgtagggcaatctgtctttaagtagggataaattactcttga ataaaatgatcctagatagttttcccttcaagtcaagcgtcttgttgtttaaataaacttcttgtttaaaatgaaaaaaa aaaaaacaaacaaacaaaaaaaagctgggagaaggtataggagaaacaggggaaggcacggccccttcccaaagcagacg gacaaatctttgggtccttcagctcccaacacaagaaagcagagatctttctatgctcagcatccttcccagggcaggga gcccctcagcccaccaatgggtactaaccagatgcttctctccccacacagctccaagaccaaggtgtctacaaggccat gaatgaatttgacatcttcatcaactgcatagaagcatacatgatgatcaaaatgaaaagctaaaacacctgcagtgtgt attgagtctgctggactccaggacctagacagagctctctaaatctgatccagggatcttagctaacggaaacaactcct tggaaaacctcgtttgtacctctctccgaaatatttattacctctgatacctcagttcccattctatttattcactgagc ttctctgtgaactatttagaaagaagcccaatattataattttacagtatttattatttttaacctgtgtttaagctgtt tccattggggacactttatagtatttaaagggagattatatta atgatgggaggggttcttccttgggaagcaattgaa gcttctattctaaggctggccacacttgagagctgcagggccctttgctatggtgtcctttcaattgctctcatccctga gttcagagctcctaagagagttgtgaagaaactcatgggtcttgggaagagaaaccagggagatcctttgatgatcattc ctgcagcagctcagagggttcccctactgtcatcccccagccgcttcatccctgaaaactgtggccagtttgttatttat aaccacctaaaattagttctaatagaactcatttttaactagaagtaatgcaattcctctgggaatggtgtattgtttgt ctgcctttgtagcagactctaattttgaataaatggatcttattcgaattacagtgtggtgtctattgagttctgtctga tttaaaagaaaaatcccttaaaattccagagggcagaagcagtgaatcttagactccacaaaaagaatgccagcaacαtc tccaggaaggggttgagctcggatcagatcagaggaaagtcttgcctggctttcaaagcatcagcataaactactgatat cttcaagctcagtcctttaaaatgtgtcctgaaaccttaaaaggcattctaccttccaaagctagggaaggtgattctaa gtaaccatcggaaggaagtgggaagcatcaaagctgaaactctgagacgaaatgttggggttaaaaatggaagctagggg caggagggtggggagatggctcagcagttagagtgtgtgccggcaccagtgagacaggagttcatatccttggaatccaa ccaacacacaaccaacactaggcaagagatgcctaatgtgtcagtggttgcttcaagctccagaggtcctggggtgaact tagatcc (SEQ ID NO: 12252) gatccccagagactttccagatatctgaagaagtcctgatgtcactgccccggtccttccccaggtagagcaacactcct cgtcgcaacccaactggctccccttaccttctacacacacacacacacacacacacacacacacacacacacacacaaat ccaagacaacactactaaggcttctttgggagggggaagtagggataggtaagaggaaagtaagggacctcctatccagc ctccatggaatcctgacttcttttccttgttatttcaacttcttccaccccatcttttaaactttagactccagccacag aagcttacaactaaaagaaactctaaggccaatttaatccaaggtttcattctatgtgctggagatggtgtacagtaggg tgaggaaaccaaattctcagttggcactggtgtacccttgtacaggtgatgtaacatctctgtgcctcagtttgctcact ataaaatagagacggtaggggtcatggtgagcactacctgactagcatataagaagctttcagcaagtgcagactactct tacccacttcccccaagcacagttggggtgggggacagctgaagaggtggaaacatgtgcctgagaatcctaatgaaatc ggggtaaaggagcctggaacacatcctgtgaccccgcctgtcctgtaggaagccagtctctggaaagtaaaatggaaggg ctgcttgggaactttgaggatatttagcccaccccctcatttttacttggggaaactaaggcccagagacctaaggtgac tgcctaagttagcaaggagaagtcttgggtattcatcccaggttggggggacccaattatttctcaatcccattgtattc tggaatgggcaatttgtccacgtcactgtgacctaggaacacgcgaatgagaacccacagctgagggcctctgcgcacag aacagctgttctccccaggaaatcaactttttttaattgagaagctaaaaaattattctaagagaggtagcccatcctaa aaatagctgtaatgcagaagttcatgttcaaccaatcatttttgcttacgatgcaaaaattgaaaactaagtttattaga gaggttagagaaggaggagctctaagcagaaaaaatcctgtgccgggaaaccttgattgtggctttttaatgaatgaaga ggcctccctgagcttacaatataaaagggggacagagaggtgaaggtctacacatcaggggcttgctcttgcaaaaccaa accacaagacagacttgcaaaagaaggcatgcacagctcagcactgcaaaccacaagacagacttgcaaaagaaggcatg cacagctcagcactgctctgttgcctggtcctcctgactggggtgagggccagcccaggccagggcacccagtctgagaa cagctgcacccacttcccaggcaacctgcctaacatgcttcgagatctccgagatgccttcagcagagtgaagactttct ttcaaatgaaggatcagctggacaacttgttgttaaaggagtccttgctggaggactttaagggttacctgggttgccaa gccttgtctgagatgatccagttttacctggaggaggtgatgccccaagctgagaaccaagacccagacatcaaggcgca tgtgaactccctgggggagaacctgaagaccctcaggctgaggctacggcgctgtcatcgatttcttccctgtgaaaaca agagcaaggccgtggagcaggtgaagaatgcctttaataagctccaagagaaaggcatctacaaagccatgagtgagttt gacatcttcatcaactacatagaagcctacatgacaatgaagatacgaaactgagacatcagggtggcgactctatagac tctaggacataaattagaggtctccaaaatcggatctggggctctgggatagctgacccagccccttgagaaaccttatt gtacctctcttatagaatatttattacctctgatacctcaacccccatttctatttatttactgagcttctctgtgaacg atttagaaagaagcccaatattataatttttttcaatatttattattttcacctgtttttaagctgtttccatagggtga cacactatggtatttgagtgttttaagataaattataagttacataagggaggaaaaaaaatgttctttggggagccaac agaagcttccattccaagcctgaccacgctttctagctgttgagctgttttccctgacctccctctaatttatcttgtct ctgggcttggggcttcctaactgctacaaatactcttaggaagagaaaccagggagcccctttgatgattaattcacctt ccagtgtctcggagggattcccctaacctcattccccaaccacttcattcttgaaagctgtggccagcttgttatttata acaacctaaatttggttctaggccgggcgcggtggctcacgcctgtaatcccagcactttgggaggctgaggcgggtgga tcacttgaggtcaggagttcctaaccagcctggtcaacatggtgaaaccccgtctctactaaaaatacaaaaattagccg ggcatggtggcgcgcacctgtaatcccagctacttgggaggctgaggcaagagaattgcttgaacccaggagatggaagt tgcagtgagctgatatcatgcccctgtactccagcctgggtgacagagcaagactctgtctcaaaaaaataaaaataaaa ataaatttggttctaatagaactcagttttaactagaatttattcaattcctctgggaatgttacattgtttgtctgtct tcatagcagattttaattttgaataaataaatgtatcttattcacatcagatcttgtaaactgtagaatgcaccctccaa aatctatttgcataagcacacacacacacacacacacacacaccccagcagttcttgcctgcccagattcctctgcagct aaagtgatgaaacttactgggcggagcttcctaaaaagattattagggtctcctgggttggtgtgcctttaaacctttgg actttaccacctcctatctctcctatctccttgcaacaaaggttaggagaacaagaatgcagaaaaaacgggtcctggat gacatctgagtgcctgctttgggcttcttgatgagtgagacagaaaataaaatacaaccccctcttttaaaagccatgct tactcaggttttccttcatttgcagctaaatacagaaatgagagaa at ttggagcagggatggaagaagagaggta ccccttcccacaaccttctgatttcccagtacatcccccactggaaaaattcatttaaaatcagtataataagcattgat tagatgcctactatgcatctgggcttgagggcaaactggactcaggccttttggcctcaagaagctcacagtgtgagagt ggcatttgtgtcctcttgaaattcacaggactaaattgtgcccaggctgacattctatccatccataggtgcctgccttc tcacttccctctcttcatgggctcttgccttgtaσcaaaatccaaacccaaatctcctcacatgtgagtgttggcattca tgtctcagacatgacctatgggcttgggacttttccccgtggaccccagtgacttttcagatgaacaggtatcttcaaaa acttgagaaataggagtcctgtttgttgttcttgttgctttgtcaatataaggcacagggtctttattcaaatgttcata ctatctcttgacagaaatactatgagacatattgatggagaagccgttatctccatatgctaaatgaggacttgcaccag ggaacttgcccatggttctctccaaccacttaaattctgaaattttgaatgagagtggacagtaatttcaaatcaatggg gaaagaatcaaatcttcagcaaatggcttgagataattagctacacatttcagaacaaataaagaagtcagatccgggcc gggcacagtggctcatgcctgtaatctcagcactctgggaggccaaggcgggcggatcataaggtcaggagatcgagacc atcctggttaacacagtgaacccctctctaataaaaatacaaaaaaaaataaaaaaacttagccgggcgtggtgccaggc gcctgtagtcccagctactcgggacgctgaggcaggagaatggcttgaactcgggaggcagagcttgcaggtgagctgag atcatgccactgcactccagcctgggcaacagagcgagactctgtctcaaaaaaaaaaaagaagtcagatcctaacctca accctatttaacagattatagatgaaagaaaggtacaaatggcttttacatacctcccttctccctgacattttgtatgt gtgtgtgtgtgtatttacacacacatctcatataaggaaattgaagggaggctgcctgcatccctgagtcactctccctc tccttctgaatgcttacctgtgcccagaccacctccttagcctcgcaccctccaggcttacagggcactcttctatgccc atcccaagtatagctgaaccttccaagggccagacttggtgctaagtaccaagtacgcaaagattaataaaacaatgtcc tgtttcagggagctcaaagctgattcggcagggcatggtgtgtacatgaatgataaccacgtagggttgcaggtttccta gtgaggtaagcacaaggcaagatgggaaacaaaggaaggaggggttcacagcctcacccagagtccagaacccctggcct gcctggtgcccatgctgagtccacttctggaacacccagctcagagagggggttagacctgcaggctaacacagacacag cccagaaaacccaggagccgagggggaaggagaaaggtgcaagaaggggaaacccaggtcctggtccccttctctctgct tcctggcagcagaactcagacagaacccttaagccagtctaagtctggcaggaccagtaagttctgagttagctccatac tagtttctagcaggctctttctcacttcctgattcttaggtttctacattgacactccctgaagagttgggaagagacac cacagtcccctgaccctgatccataggtcacacagcaggcatccacagggtgggcgtgggccctctcatccctccctccc actcacttcacgctggctgggccccaaggtgtttgcaccccttgcagtgagtgaccttctctagtgcagcaagctcagaa cctgctgccactggagttgtcccattgctgatgcagaaaggtgaagaactagcagaacactggaaatgccctccatctgg gtccatggctacttaatgctccctggcaggcaggaggacaggtgctattccctgttgggacagatgaaaaacagacacag ggaggatgagtgatttgccctgactatagagtggcagggccaaggcagagcccaggcctcctgcacctaggtcagtgttc ctcccagttacagtctaaactggaatgcaggcaaagcccctgtggaaggggaaggtgaaggctcaatcaaaggatcccca gagactttccagatatctgaagaagtcctgatgtcactgccccggtccttccccaggtagagcaacactcctcgccgcaa cccaactggctccccttaccttctacacacacacacacacacacacacacacacacacacacacacaaatccaagacaac actactaaggcttctttgggaaggggaagtagggataggtaagaggaaagtaagggacctcctatccagcctccatggaa tcctgacttcttttccttgttatttcaacttcttccaccccatcttttaaactttagactccagccacagaagcttacaa ctaaaagaaac ctaaggccaatttaatccaaggtttcattctatgtgctggagatggtgtacagtagggtgaggaaacc aaattctcagttggcactggtgtacccttgtacaggtgatgtaacatctctgtgcctcagtttgctcactataaaataga gacggtaggggtcatggtgagcactacctgactagcatataagaagctttcagcaagtgcagactactcttacccacttc ccccaagcacagttggggtgggggacagctgaagaggtggaaacatgtgcctgagaatcctaatgaaatcggggtaaagg agcctggaacacatcctgtgaccccgcctgtcctgtaggaagccagtctctggaaagtaaaatggaagggctgcttggga actttgaggatatttagcccaccccctcatttttacttggggaaactaaggcccagagacctaaggtgactgcctaagtt agcaaggagaagtcttgggtattcatcccaggttggggggacccaattatttctcaatcccattgtattctggaatgggc aatttgtccacgtcactgtgacctaggaacacgcgaatgagaacccacagctgagggcctctgcgcacagaacagctgtt ctccccaggaaatcaactttttttaattgagaagctaaaaaattattctaagagaggtagcccatcctaaaaatagctgt aatgcagaagttcatgttcaaccaatcatttttgcttacgatgcaaaaattgaaaactaagtttattagagaggttagag aaggaggagctctaaggagaaaaaatcctgtgccgggaaaccttgattgtggctttttaatgaatgaagaggcctccctg agcttacaata aaaagggggacagagaggtgaaggtctacacatcaggggcttgctcttgcaaaaccaaaccacaagac agacttgcaaaagaaggcatgcacagctcagcactgctctgttgcctggtcctcctgactggggtgagggccagcccagg ccagggcacccagtctgagaacagctgcacccacttcccaggcaacctgcctaacatgcttcgagatctgggggggggga tttagagacttgctcttgcactaccaaagccacaaagcagccttgcagaaaagagagctccatcatgcctggctcagcac tgctatgctgcctgctcttactgactggcatgaggatcagcaggggccagtacagccgggaagacaataactgcacccac ttcccagtcggccagagccacatgctcctagagctgcggactgccttcagccaggtgaagactttctttcaaacaaagga ccagctggacaacatactgctaaccgactccttaatgcaggactttaagggttacttgggttgccaagccttatcggaaa tgatccagttttacctggtagaagtgatgccccaggcagagaagcatggcccagaaatcaaggagcatttgaattccctg ggtgagaagctgaagaccctcaggatgcggctgaggcgctgtcatcgatttctcccctgtgaaaataagagcaaggcagt ggagcaggtgaagagtgattttaataagctccaagaccaaggtgtctacaaggccatgaatgaatttgacatcttcatca actgcatagaagcatacatgatgatcaaaatgaaaagctaaaacacctgcagtgtgtattgagtctgctggactccagga cctagacagagctctctaaatctgatccagggatcttagctaacggaaacaactccttggaaaacctcgtttgtacctct ctccgaaa atttattacctctgatacctcagttcccattctatttattcactgagcttctctgtgaactatttagaaag aagcccaatattataattttacagtatttattatttttaacctgtgtttaagctgtttccattggggacactttatagta tttaaagggagattatattatatgatgggaggggttcttccttgggaagcaattgaagcttctattctaaggctggccac acttgagagctgcagggccctttgctatggtgtcctttcaattgctctcatccctgagttcagagctcctaagagagttg tgaagaaactcatgggtcttgggaagagaaaccagggagatcctttgatgatcattcctgcagcagctcagagggttccc ctactg ca cccccagccgcttcatccctgaaaactgtggccagtttgttatttataaccacctaaaattagttctaat agaactcatttttaactagaagtaatgcaattcctctgggaatggtgtattgtttgtctgcctttgtagcagcatctaat tttgaataaatggatcttattcgcagtcaggagagagggcagtgagggtccatgctagctgggtcttgagcctcttctgg ggttcagtctctgatctacagcagtgtgtccacacctaaaacatcagctcagagaggcagttgcttctgctgttggaaac ggacatcccaaaaaaaaacaaaaaacagaaatcaaaagggaaggagaaagtgaaagggatggaggcagcttgtccccttc cctgtgcttgctgctggtagaaaactcagcctggaactgaccggagcagcagttcttgagtcaattccattccaacttct agaagattcttttcccgtcgaagagtgtcaggaggagaggccagacccccttgatcctgatctgccagccactgcatcag ataagacgagataaccccgagttcctgttctaccagccctggtgtggtaaccctctccaatggggcaggcttggaaccct gtgccaacgaagatcctcccccgtactgatgcaggaaggacagcccgggagtgtaccctctacatgggtctacttttatt taagcaaacattccctggtcaacaggacgtgtagcattgcccccccccttgggtcacacagaaaacaggtaccaggagga caagtagttgcttgcccagggtacagaatgaaaggcaataggggactctaggcgaatgttcttcccacccaaactgaggt agtaggagaagtccctactgaagggaaggtccagacataatcaaaggactaccagagatctcccaggtatctgtagaagt actaacatctccatccttcaacagctacaggttacacgtctccaaggctgggacattgtaaaacagggccatggtaaggt ctacccgacagcacagagcaagcctcccagaagtctgagttccttctcctaacttctcatgctgggatctgagcttcttc

• gtgaaacacggggcagaggaggcaccagaactctcctctgaccaactgccccacagcacacatatcctcaaaggatagtc ttgaatacgtgatggaagaattaaagagagtgaggtctgaagaaaatcagccctctcggggtttcctttgggtaactgag tgctaaggtgacttccgagtcagcaagaaatatcggacgttcaacccaggttgagtggaggaaacaattatttctcaatc ctaatatgttctggaatagcccatttatccacgtcattatgacctgggagtgcgtgaatggaatccacagatgagggcct ctgtacatagaacagctgtctgcctcaggaaatacaacttttagtattgagaagctaaaaagaaaaaaaaattaaaagag aggtagcccatactaaaaatagctgtaatgcagaagttcattccgaccagttctttagcgcttacaatgcaaaaaaaagg gaaaggaaaaaaaaaaagaaagaaattaaactcaaaaattgcatggtttagaagagggaggaggagcctgaataacaaaa acctttgccaggaaggccccactgagccttcagtataaaagggggaccaagaacaggaggtctacatttagagacttgct cttgcactaccaaagccacaaggcagccttgcagaaaagagagctccatcatgcctggctcagcactgctatgctgcctg ctcttactgactggcatgaggatcagcaggggccagtacagccgggaagacaataactgcacccacttcccagtcggcca gagccacatgctcctagagctgcggactgccttcagccaggtgaagactttctttgtaagtatgagctcgcctagccttt cttcctgccatcacctgaaatatgcattctgatggaactgcaaaaatagctctccttctcctcctccttctcctccttct ctttctcctcctctgctttctcctccttctcttcctcctccttctcttcttcctcctctccctcttcctcctccagctct tacctcatgctgctcctcccctatttccagcacctattacccttaaacttaaatctagagagtcctagggaaagccatga gttaaactaaacccaggcacatccgaaaagctaactaggaggtgaatgcattgtctctcccatgctcaagaactttctgt taagtttccaataaggctccatgttttgctggctaggacaaaagtctgtggtctctgcgtagtctctagatctgggggac agaggtttgggggtttgaagcagcaccagcatagagagcttgcattacaaaagtattcccctttcagagctcctggaact ggtatggaggtccaaagaaggcagagagctatgcaaaacaggctttctataagggactccagaaaggaagggttgacaca ggtgctcttgaaacctgatctgactcatctgaaagaagaccgggcctgggtctaacttctcccagtcagttaaattcagt cagaagtttttaaaaacaactggatcccaagaggaaggactttgatttaactccgggctctagcactgtcaaatcctgtt cttaaaactctcctttccacagttgccagggcatttgaattgattacaaattcaaaactctacaaatggaaaagtattca aatgacatgcacattgggtattttccccagtccttgcattcacgttctttatgttcttccagcaaacaaaggaccagctg gacaacatactgctaaccgactccttaatgcaggactttaaggtaagagtccggtgggtgctggggagcgaccaagcgat tagggacgggacgggaggtgctgcttgtgacagcagagctgggtctgatgccttgactttcaaaaagagaagtgagaaga ccttgactcagcatatcgccagcagtcaagggttgtgaagagctcattctgtggtaaagggagaaaatgtaactagaagg ggcggggatggggggggggtccctaggaacaggacagtccatcaaggttagcagcaacagatcaccattccagtaagtca cacccaacctctgatccctgcctctagggttacttgggttgccaagccttatcggaaatgatccagttttacctggtaga agtgatgccccaggcagagaagcatggcccagaaatcaaggagcatttgaattccctgggtgagaagctgaagaccctca ggatgcggctgaggcgctgtgtgagtagcagatgcgttcttccccacccccaatccccttagagccacccaacaaatact gtctcctacagcccagtcaggccacatgcatccagagacacacacagactagacaggagactaggtaaatctagagagac gcctgtccggtgtcgggtctcttgctcatctgtctctgagcgagtgtgggagtgactttgaggcactcacacgtgaagat ttgcgcatagccttcctgttatttgtgagtcattgtgggttattagctactcccctctctctccatgggaaggctggggc ttcagtcatggctccctcacctctgggctgccagctgaggctcccaagcacaggaaaacattcatctctt atctcatct tttgggaagcaaattcagtggcacagagctgggctgacaggacgctggtgtttcagaagggccagaagactgctatccct aagccagtatctatgaataatacagtcggggcatctatgtctctgaagcgatgccttggctgctcttgtttttcttactt ctctcactgatactgggacatcagctggagtctacttgtgcaacggttctggcctgacgatttggccccagtagctgaga ctttcgctcctctctcagacacctagaaatagttcatggtggttgagattggagatagacaagaagagacactaaaaaca gaacaggtgccttggagctctgagagacaaaacccgagacctgagttcacacccacacttagcaagccatcttagtgatt gcaaagacatacattgcatctttctaggctgtcctctgctgtccccctcagtccctaccgaaatagataaggaccaatca cggctcagttctccctgggagctaagaagtgggcattgaagatgagcaagggtgtctccttcctcacacaacaagatagt ttcccccaagtaccatggatgcagaattcaagcaagaattaccaatgctctcttttttcttcttcagcatcgatttctcc cctgtgaaaataagagcaaggcagtggagcaggtgaagagtgattttaataaggtaagtggcaaagggggcgagtgtaac aagacctctgtctactcaccaaagcgcagaaggagggcgggagctattctgcacctggagtgtgggaacccagcaaatgg tgtgacctcctctgccagttagaaagccaccacctcagttacatttgttttctgcaaagcgtctctggcagtttctaaat gactgctccacttttgcaggcttttggcttagactgaccagacagcctatgagcacagggcactaggtgttgaggagagt gacataggaaacagaaagtacagaaagtaccttgttgggaaacaggctgaacccacaagtacagaaagcagacatgaatt aatttactcaggtacatcattggggctcagcctggatgcccctcccccaaatcagaacgagcagaaagcagaattcttac ttgtcccggggcactttccacctggcaaacaaaatgaggtttcacacttccaactgcctgtgaacctattcaaccctagt tcccagaagccatgtggcctacatcatca ctttgtgggctaggcagagacacctggcagggctctaacattagtgggca tgaattccatgacagcaggtcagagctgcagggtgaggactgcctacacactcaaaacataaaaaaaaaaaaaaaaaaac accaaccatttccctgctatctctatcactgccctgcttacaaactgctccctctggcatctttgcataacattctgcat aagcattatatgagcactggcctcttaaaaaaaattagttgaaaaggtgccaccctgaagacagtgctttggggactgaa tgcttcccttgctgactcctggcagtgcttaaagctgggagaaggttggtcccaccacatcctgactactacagtatagt tgtctctcttctttcatttccctgtccccatttctttattgtacataaagtaactggtgtatgtgcacacacatagtgct ctctctttcttttccttttttaaactaaatggccgatgttctgttctggttggcatcagatggagatggtctgggggaaa gtactgggtttgtgaaaatacccccttctccattagtggcatgctctttcagctcttatctttatattccagtaagttat tttgctctcattgttttaacaaaagaacccaacaacaccaaatctttgcataccttgttcgattggagaattttaatgtt tttcatttatcattgtaaaaccgaggacaattttataacttttttgtacgtggctgttacatgtagggcaatctgtcttt aagtagggataaat actcttgaataaaatgatcctagatagttttcccttcaagtcaagcgtcttgttgtttaaataaa cttcttgtttaaaatgaaaaaaaaaaaaacaaacaaacaaaaaaaagctgggagaaggtataggagaaacaggggaaggc acggccccttcccaaagcagacggacaaatctttgggtccttcagctcccaacacaagaaagcagagatctttctatgct cagcatccttcccagggcagggagcccctcagcccaccaatgggtactaaccagatgcttctctccccacacagctccaa gaccaaggtgtctacaaggccatgaatgaatttgacatcttcatcaactgcatagaagcatacatgatgatcaaaatgaa aagctaaaacacctgcagtgtgtattgagtctgctggactccaggacctagacagagctctctaaatctgatccagggat cttagctaacggaaacaactccttggaaaacctcgtttgtacctctctccgaaatatttattacctctgatacctcagtt cccattctatttattcactgagcttctctgtgaactatttagaaagaagcccaatattataattttacagtatttattat ttttaacctgtgtttaagctgtttccattggggacactttatagtatttaaagggagattatattatatgatgggagggg ttcttccttgggaagcaattgaagcttctattctaaggctggccacacttgagagctgcagggccctttgctatggtgtc ctttcaattgctctcatccctgagttcagagctcctaagagagttgtgaagaaactcatgggtcttgggaagagaaacca gggagatcctttgatgatcattcctgcagcagctcagagggttcccctactgtcatcccccagccgcttcatccctgaaa actgtggccagtttgttatttataaccacctaaaattagttctaatagaactcatttttaactagaagtaatgcaattcc tctgggaatggtgtattgtttgtctgcctttgtagcagactctaattttgaataaatggatcttattcgaattacagtgt ggtgtctattgagttctgtctgatttaaaagaaaaatcccttaaaattccagagggcagaagcagtgaatcttagactcc acaaaaagaatgccagcaacctctccaggaaggggttgagctcggatcagatcagaggaaagtcttgcctggctttcaaa gcatcagcataaactactgatatcttcaagctcagtcctttaaaatgtgtcctgaaaccttaaaaggcattctaccttcc aaagctagggaaggtgattctaagtaaccatcggaaggaagtgggaagcatcaaagctgaaactctgagacgaaatgttg gggttaaaaatggaagctaggggcaggagggtggggagatggctcagcagttagagtgtgtgccggcaccagtgagacag gagttcatatccttggaatccaaccaacacacaaccaacactaggcaagagatgcctaatgtgtcagtggttgcttcaag ctccagaggtcctggggtgaacttagatcc (SEQ ID NO: 12253) aaagagctggaggcgcgcaggccggctccgctccggccccggacgatgcggcgcgcccaggatgctgccgtgcctcgtag tgctgctggcggcgctcctcagcctccgtcttggctcagacgctcatgggacagagctgcccagccctccgtctgtgtgg tttgaagcagaatttttccaccacatcctccactggacacccatcccaaatcagtctgaaagtacctgctatgaagtggc gctcctgaggtatggaatagagtcctggaactccatctccaactgtagccagaccctgtcctatgaccttaccgcagtga ccttggacctgtaccacagcaatggctaccgggccagagtgcgggctgtggacggcagccggcactccaactggaccgtc accaacacccgcttctctgtggatgaagtgactctgacagttggcagtgtgaacctagagatccacaatggcttcatcct cgggaagattcagctacccaggcccaagatggcccccgcgaatgacacatatgaaagcatcttcagtcacttccgagagt atgagattgccattcgcaaggtgccgggaaacttcacgttcacacacaagaaagtaaaacatgaaaacttcagcctccta acctctggagaagtgggagagttctgtgtccaggtgaaaccatctgtcgcttcccgaagtaacaaggggatgtggtctaa agaggagtgcatctccctcaccaggcagta tcaccgtgaccaacgtcatcatcttctttgcctttgtcctgctgctct ccggagccctcgcctactgcctggccctccagctgtatgtgcggcgccgaaagaagctacccagtgtcctgctcttcaag aagcccagccccttcatcttcatcagccagcgtccctccccagagacccaagacaccatccacccgcttgatgaggaggc ctttttgaaggtgtccccagagctgaagaacttggacctgcacggcagcacagacagtggctttggcagcaccaagccat ccctgcagactgaagagccccagttcctcctccctgaccctcacccccaggctgacagaacgctgggaaacggggagccc cctgtgctgggggacagctgcagtagtggcagcagcaatagcacagacagcgggatctgcctgcaggagcccagcctgag ccccagcacagggcccacctgggagcaacaggtggggagcaacagcaggggccaggatgacagtggcattgacttagttc aaaactctgagggccgggctggggacacacagggtggctcggccttgggccaccacagtcccccggagcctgaggtgcct ggggaagaagacccagctgctgtggcattccagggttacctgaggcagaccagatgtgctgaagagaaggcaaccaagac aggctgcctggaggaagaatcgcccttgacagatggccttggccccaaattcgggagatgcctggttgatgaggcaggct tgcatccaccagccctggccaagggctatttgaaacaggatcctctagaaatgactctggcttcctcaggggccccaacg ggacagtggaaccagcccactgaggaatggtcactcctggccttgagcagctgcagtgacctgggaatatctgactggag ctttgcccatgaccttgcccctctaggctgtgtggcagccccaggtggtctcctgggcagctttaactcagacctggtca ccctgcccctcatctctagcctgcagtcaagtgagtgactcgggctgagaggctgcttttgattttagccatgcctgctc ctctgcctggaccaggaggagggccctggggcagaagttaggcacgaggcagtctgggcacttttctgcaagtccactgg ggctggcccagccaggctgcagggctggtcagggtgtctggggcaggaggaggccaactcactgaactagtgcagggtat gtgggtggcactgacctgttctgttgactggggccctgcagactctggcagagctgagaagggcagggaccttctccctc ctaggaactctttcctgtatcataaaggattatttgctcaggggaaccatggggctttctggagttgtggtgaggccacc aggctgaagtcagctcagacccagacctccctgcttaggccactcgagcatcagagcttccagcaggaggaagggctgta ggaatggaagcttcagggccttgctgctggggtcatttttaggggaaaaaggaggatatgatggtcacatggggaacctc ccctcatcgggcctctggggcaggaagcttgtcactggaagatcttaaggtatatattttctggacactcaaacacatca taatggattcactgaggggagacaaagggagccgagaccctggatggggcttccagctcagaacccatccctctggtggg tacctctggcacccatctgcaaatatctccctctctccaacaaatggagtagcatccccctggggcacttgctgaggcca agccactcacatcctcactttgctgccccaccatcttgctgacaacttccagagaagccatggttttttgtattggtcat aactcagccctttgggcggcctctgggcttgggcaccagctcatgccagccccagagggtcagggttggaggcctgtgct tgtgtttgctgctaatgtccagctacagacccagaggataagccactgggcactgggctggggtccctgccttgttggtg tgtttcttatgccagaggctaacagatccaatgggagtccatggtgtcatgccaagacagtatcagacacagccccagaa gggggcattatgggccctgcctccccataggccatttggactctgccttcaaacaaaggcagttcagtccacaggcatgg aagctgtgaggggacaggcctgtgcgtgccatccagagtcatctcagccctgcctttctctggagcattctgaaaacaga tattctggcccagggaatccagccatgacccccacccctctgccaaagtactcttaggtgccagtctggtaactgaactc cctctggaggcaggcttgagggaggattcctcagggttcccttgaaagctttatttatttattttgttcatttatttatt ggagaggcagcattgcacagtgaaagaattctggatatctcaggagccccgaaattctagctctgactttgctgtttcca gtggtatgaccttggagaagtcacttatcctcttggagcctcagtttcc catctgcagaataatgactgacttgtctaa ttcatagggatgtgaggttctgctgaggaaatgggtatgaatgtgccttgaacacaaagctctgtcaataagtgatacat gttttttattccaataaattgtcaagaccaca (SEQ ID NO: 12254) gctgtagctggtgagaggaagtcctagaggctatggacactctgctgctgggatcaccgagatgagcagcagctgctcag ggctgagcagggtcctggtggccgtggctacagccctggtgtctgcctcctccccctgcccccaggcctggggcccccca ggggtccagtatgggcagccagggaggtccgtgaagctgtgttgtcctggagtgactgccggggacccagtgtcctggtt tcgggatggggagccaaagctgctccagggacctgactctgggctagggcatgaactggtcctggcccaggcagacagca ctgatgagggcacctacatctgccagaccctggatggtgcacttgggggcacagtgaccctgcagctgggctaccctcca gcccgccctgttgtctcctgccaagcagccgactatgagaacttctcttgcacttggagtcccagccagatcagcggttt acccacccgctacctcacctcctacaggaagaagacagtcctaggagctgatagccagaggaggagtccatccacagggc cctggccatgcccacaggatcccctaggggctgcccgctgtgttgtccacggggctgagttctggagccagtaccggatt aatgtgactgaggtgaacccactgggtgccagcacacgcctgctggatgtgagcttgcagagcatcttgcgccctgaccc accccagggcctgcgggtagagtcagtaccaggttacccccgacgcctgcgagccagctggacataccctgcctcctggc cgtgccagccccacttcctgctcaagttccgtttgcagtaccgtccggcgcagcatccagcctggtccacggtggagcca gctggactggaggaggtgatcacagatgctgtggctgggctgccccatgctgtacgagtcagtgcccgggactttctaga tgctggcacctggagcacctggagcccggaggcctggggaactccgagcactgggaccataccaaaggagataccagcat ggggccagctacacacgcagccagaggtggagcctcaggtggacagccctgctcctccaaggccctccctccaaccacac cctcggctacttgatcacagggactctgtggagcaggtagctgtgctggcgtctttgggaatcctttctttcctgggact ggtggctggggccctggcactggggctctggctgaggctgagacggggtgggaaggatggatccccaaagcctgggttct tggcctcagtgattccagtggacaggcgtccaggagctccaaacctgtagaggacccaggagggcttcggcagattccac ctataattctgtcttgctggtgtggatagaaaccaggcaggacagtagatccctatggttggatctcagctggaagttct gtttggagcccatttctgtgagaccctgtatttcaaatttgcagctgaaaggtgcttgtacctctgatttcaccccagag ttggagttctgctcaaggaacgtgtgtaatgtgtacatctgtgtccatgtgtgaccatgtgtctgtgaaggccagggaac atgtattcctctgcatgcatgtatgtaggtgcctgggagtgtgtgtggtccttgctctggccctttcccttgcagggttg tgcaggtgtgaataaa (SEQ ID NO: 12255) ggaagatgagcagcagctgctcagggctgagcagggtcctggtggccgtggctacagccctggtgtctgcctcctccccc tgcccccaggcctggggccccccaggggtccagtatgggcagccaggcaggtccgtgaagctgtgttgtcctggagtgac tgccggggacccagtgtcctggtttcgggatggggagccaaagctgctccagggacctgactctgggctagggcatgaac tggtcctggcccaggcagacagcactgatgagggcacctacatctgccagaccctggatggtgcacttgggggcacagtg accctgcagctgggctaccctccagcccgccctgttgtctcctgccaagcagccgactatgagaacttctcttgcacttg gagtcccagccagatcagcggtttacccacccgctacctcacctcctacaggaagaagacagtcctaggagctgatagcc agaggaggagtccatccacagggccctggccatgcccacaggatcccctaggggctgcccgctgtgttgtccacggggct gagttctggagccagtaccggattaatgtgactgaggtgaacccactgggtgccagcacacgcctgctggatgtgagctt gcagagcatcttgcgccctgacccaccccagggcctgcgggtagagtcagtaccaggttacccccgacgcctgcgagcca gctggacataccctgcctcctggccgtgccagccccacttcctgctcaagttccgtttgcagtaccgtccggcgcagcat ccagcctggtccacggtggagccagctggactggaggaggtgatcacagatgctgtggctgggctgccccatgctgtacg agtcagtgcccgggactttctagatgctggcacctggagcacctggagcccggaggcctggggaactccgagcactggga ccataccaaaggagataccagcatggggccagctacacacgcagccagaggtggagcctcaggtggacagccctgctcct ccaaggccctccctccaaccacaccctcggctacttgatcacagggactctgtggagcaggtagctgtgctggcgtcttt gggaatcctttctttcctgggactggtggctggggccctggcactggggctctggctgaggctgagacggggtgggaagg atggatccccaaagcctgggttcttggcctcagtgattccagtggacaggcgtccaggagctccaaacctgtagaggacc caggagggcttcggcagattccacctataattctgtcttgctggtgtggatagaaaccaggcaggacagtagatccctat ggttggatctcagctggaagttctgtttggagcccatttctgtgagaccctgtatttcaaatttgcagctgaaaggtgct tctacctctgatttcaccccagagttggagttctgctcaaggaacgtgtgtaatgtgtacatctgtgtccatgtgtgacc atgtgtctgtgaggcagggaacatgtattctctgcatgcatgtatgtaggtgcctggggagtgtgtgtgggtccttggct cttggcctttccttgcaggggttgtgcaggtgtgaataaagagaataaggaagttcttggagattatactcagaaaaaaa aa (SEQ ID NO: 12256) tctgtggagcaggtagctgtgctggcgtctttgggaatcctttctttcctgggactggtggctggggccctggcactggg gctctggtaagtgactgccattggtccctcagcctctgatcctcacacatgctctgatgcccatagaccacattcatctc cacccttcatgactgcctgctgaacctgtctgattctggaactacctccccatacctccatcccctatgccccacttgat tttaactgattcctctcctgaccctttactaataaaccctttggcggagactgagataacccacattgttggagagacag ctgcctttctatgccccaggctgaggctgagacggggtgggaaggatggatccccaaagcctgggttcttggcctcagtg attccagtggaca (SEQ ID NO:12257) gctgtagctggtgagaggaagtcctagaggctatggacactctgctgctgggatcaccgagatgagcagcagctgctcag ggctgagcagggtcctggtggccgtggctacagccctggtgtctgcctcctccccctgcccccaggcctggggcccccca ggggtccagtatgggcagccagggaggtccgtgaagctgtgttgtcctggagtgactgccggggacccagtgtcctggtt tcgggatggggagccaaagctgctccagggacctgactctgggctagggcatgaactggtcctggcccaggcagacagca ctgatgagggcacctacatctgccagaccctggatggtgcacttgggggcacagtgaccctgcagctgggctaccctcca gcccgccctgttgtctcctgccaagcagccgactatgagaacttctcttgcacttggagtcccagccagatcagcggttt acccacccgctacctcacctcctacaggaagaagacagtcctaggagctgatagccagaggaggagtccatccacagggc cctggccatgcccacaggatcccctaggggctgcccgctgtgttgtccacggggctgagttctggagccagtaccggatt aatgtgactgaggtgaacccactgggtgccagcacacgcctgctggatgtgagcttgcagagcatcttgcgccctgaccc accccagggcctgcgggtagagtcagtaccaggttacccccgacgcctgcgagccagctggacataccctgcctcctggc cgtgccagccccacttcctgctcaagttccgtttgcagtaccgtccggcgcagcatccagcctggtccacggtggagcca gctggactggaggaggtgatcacagatgctgtggctgggctgccccatgctgtacgagtcagtgcccgggactttctaga tgctggcacctggagcacctggagcccggaggcctggggaactccgagcactgggaccataccaaaggagataccagcat ggggccagctacacacgcagccagaggtggagcctcaggtggacagccctgctcctccaaggccctccctccaaccacac cctcggctacttgatcacagggactctgtggagcaggtagctgtgctggcgtctttgggaatcctttctttcctgggact ggtggctggggccctggcactggggctctggctgaggctgagacggggtgggaaggatggatccccaaagcctgggttct tggcctcagtgattccagtggacaggcgtccaggagctccaaacctgtagaggacccaggagggcttcggcagattccac ctataattctgtcttgctggtgtggatagaaaccaggcaggacagtagatccctatggttggatctcagctggaagttct gtttggagcccatttctgtgagaccctgtatttcaaatttgcagctgaaaggtgcttgtacctctgatttcaccccagag ttggagttctgctcaaggaacgtgtgtaatgtgtacatctgtgtccatgtgtgaccatgtgtctgtgaaggccagggaac atgtattcctctgcatgcatgtatgtaggtgcctgggagtgtgtgtggtccttgctctggccctttcccttgcagggttg tgcaggtgtgaataaaggaagatgagcagcagctgctcagggctgagcagggtcctggtggccgtggctacagccctggt gtctgcctcctccccctgcccccaggcctggggccccccaggggtccagtatgggcagccaggcaggtccgtgaagctgt gttgtcctggagtgactgccggggacccagtgtcctggtttcgggatggggagccaaagctgctccagggacctgactct gggctagggcatgaactggtcctggcccaggcagacagcactgatgagggcacctacatctgccagaccctggatggtgc acttgggggcacagtgaccctgcagctgggctaccctccagcccgccctgttgtctcctgccaagcagccgactatgaga acttctcttgcacttggagtcccagccagatcagcggtttacccacccgctacctcacctcctacaggaagaagacagtc ctaggagctgatagccagaggaggagtccatccacagggccctggccatgcccacaggatcccctaggggctgcccgctg tgttgtccacggggctgagttctggagccagtaccggattaatgtgactgaggtgaacccactgggtgccagcacacgcc tgctggatgtgagcttgcagagcatcttgcgccctgacccaccccagggcctgcgggtagagtcagtaccaggttacccc cgacgcctgcgagccagctggacataccctgcctcctggccgtgccagccccacttcctgctcaagttccgtttgcagta ccgtccggcgcagcatccagcctggtccacggtggagccagctggactggaggaggtgatcacagatgctgtggctgggc tgccccatgctgtacgagtcagtgcccgggactttctagatgctggcacctggagcacctggagcccggaggcctgggga actccgagcactgggaccataccaaaggagataccagcatggggccagctacacacgcagccagaggtggagcctcaggt ggacagccctgctcctccaaggccctccctccaaccacaccctcggctacttgatcacagggactctgtggagcaggtag ctgtgctggcgtctttgggaatcctttctttcctgggactggtggctggggccctggcactggggctctggctgaggctg agacggggtgggaaggatggatccccaaagcctgggttcttggcctcagtgattccagtggacaggcgtccaggagctcc aaacctgtagaggacccaggagggcttcggcagattccacctataattctgtcttgctggtgtggatagaaaccaggcag gacagtagatccctatggttggatctcagctggaagttctgtttggagcccatttctgtgagaccctgtatttcaaattt gcagctgaaaggtgcttctacctctgatttcaccccagagttggagttctgctcaaggaacgtgtgtaatgtgtacatct gtgtccatgtgtgaccatgtgtctgtgaggcagggaacatgtattctctgcatgcatgtatgtaggtgcctggggagtgt gtgtgggtccttggctcttggcctttccttgcaggggttgtgcaggtgtgaataaagagaataaggaagttcttggagat tatactcagaaaaaaaaatctgtggagcaggtagctgtgctggcgtctttgggaatcctttctttcctgggactggtggc tggggccctggcactggggctctggtaagtgactgccattggtccctcagcctctgatcctcacacatgctctgatgccc at gaccacattcatctccacccttcatgactgcctgctgaacctgtctgattctggaactacctccccatacctccatc ccctatgccccacttgattttaactgattcctctcctgaccctttactaataaaccctttggcggagactgagataaccc acattgttggagagacagctgcctttctatgccccaggctgaggctgagacggggtgggaaggatggatccccaaagcct gggttcttggcctcagtgattccagtggaca (SEQ ID NO: 12258) atgtggccccctgggtcagcctcccagccaccgccctcacctgccgcggccacaggtctgcatccagcggctcgccctgt gtccctgcagtgccggctcagcatgtgtccagcgcgcagcctcctccttgtggctaccctggtcctcctggaccacctca gtttggccagaaacctccccgtggccactccagacccaggaatgttcccatgccttcaccactcccaaaacctgctgagg gccgtcagcaacatgctccagaaggccagacaaactctagaattttacccttgcacttctgaagagattgatcatgaaga tatcacaaaagataaaaccagcacagtggaggcctgtttaccattggaattaaccaagaatgagagttgcctaaattcca gagagacctctttcataactaatgggagttgcctggcctccagaaagacctcttttatgatggccctgtgccttagtagt atttatgaagacttgaagatgtaccaggtggagttcaagaccatgaatgcaaagcttctgatggatcctaagaggcagat ctttctagatcaaaacatgctggcagttattgatgagctgatgcaggccctgaatttcaacagtgagactgtgccacaaa aatcctcccttgaagaaccggatttttataaaactaaaatcaagctctgcatacttcttcatgctttcagaattcgggca gtgactattgatagagtgatgagctatctgaatgcttcctaa (SEQ ID NO: 12259) aagcttcttttgcataactggcgctggatttttactgagactttacgttacagttttttttttttaaatttcaaggtgct tttacgaacacatgaataaaatatttgtgtcattttgaaccttacttgtcttattttatgcatgtatttatttatggggg ggcacaaggactcatctgtggtggtgcagccactgtaaataaattagtgaaactacttcacgtcaatttctgttcagtac actttagtgatggatcggaggaaattaatacatgtttacaaaaagcccctcccccagttgttacatatgcctcagagata ccagttgtgaaaagtgcaggtgcacttacacacatacgcacacacaccccacaaatggtatcatacgaaaaaacatacct gcaatctgatttgtccacttaattgtatatcttggatacagaacttgtttcactggaaggctaaaaggcaaagtctgggg aggcctagaggacacaggggatgggaggaggcgctctgagctggatgtaaggtctccacccacggccagagcacaaggtc ggataaccagtgggcctgccggcttggctgcctgggccctcccctgccgagacaaacggctggagggaggaagtgtgcgg ctgggaagctccgctgctctggcccgggtttcccatttcccccttcccgcgctgagacggcgaggaaagttagcccggaa atctgcgcccgcctaaaacccggcctggtcccagccaccgccccaggaacttcccccaccgcaggggcggaggtcgagag cagggatggagaagtggacctgcgcgggtggactccggggcgcgggtggactccggggcgcggggggactccgaggagcg ggtggactgtggggcgcgggtaccgtctcgcagcgacctctgtcggcggctctggggatggcccgcatctgtctgcgtgt acctggtatacgtgcaggtacatgttcctgttcacgtgcagactgggcgggggatgggggggtccacaccggtgtacacc tttgcatacctcttagcaacttgaaattccaccacgagagatatctttattccgctattcctgtgcatctgcacggagcc cctagggccatagatttgtgtgcaaatgaaatgaggatgtagtctgggtgcccaagggggggtgccttgagtgtggttgt ctgtatgcctccctgagggtatttcactttctgctcccatccgcccctatgagcgagtacctatgagcacaggatgtgca catatttgagtcttattagtggtacacgcagttttatcatctccccaggtctgtgtctgtatgaaatgtgcatgggtgtg tgtgtgcacgcgtgtgttcccactcggggaatgtggggagaggtgcatggagccaagatgggtggtaaatagtatgtttc tgaaattaaaggactaatgtggaggaaggcgccccagatgtactaaaccctttgccttcatctcatcctctctgacttgg gaagaaccaggattttgtttttaagcccttgggcatacagttgttccatcccgacatgaactcagcctcccgtctgaccg ccccttggccttccttcttcctcgatctgtggaacccagggaatctgcctagtgctgtctccaagcaccttggccatgat gtaaacccagagaaattagcatctccatctccttccttattccccacccaaaagtcat tcctcttagttcattacctgg gattttgatgtctatgttccctcctcgttattgatacacacacagagagagacaaacaaaaaaggaacttcttgaaattc ccccagaaggttttgagagttgttttcaatgttgcaacaagtcagtttctagtttaagtttccatcagaaaggagtagag t tataagttccagtaccagcaacagcagcagaagaaacaacatctgtttcagggccattggactctccgtcctgcccag agcaaggtaagcacttcccaagcccctacctccctcccctccctgtgggcctgcag (SEQ ID NO:12260) gaattctcagacagcagcattagaaggggccttagagatcaaccatttctcttattttacacacacctaaaactccctac agccgtgct catcagcttcgagcagatgagccacccagaaggcagctccagttattaggtcctagggcctgggtgtagt caggccctttggaagctccaagtcagagatcaaacacatcctccccactacccacgcctagggtgactaatgcctgtggg aaaaacaactgaactaaaaagtcccacaggaacctcaaacccagcacatccaaaatggaacttctcaccatctcctccaa actcagtcctcttatacagtaatccctgtaaagctagaacaatctccattccccattctcagggccttcctctcccgctc acctgaggagctaccaagccttggcccacaagccctctgagagtccctcctgcccaccctgtgttctccatactgaataa ggacttggccacaccttgtcaactcttccctctgctctactcctgacccctggatccccccatcatgcaaattctgccac atctcccgcctaaaacccaggaagactccccactactctcagcacagaaagtacactccttagtatggcatcccctgccc tcatggcatggcccatccagccctccagcctcacaccctgcaaggacacctagacccccacctccctcaacccttcatga ctgcgcttctgatccctgtttcccctggctagaccctgcgtgccctcccgctggaagcggtctaatgcctgcttgttttt aacactcaggttggggcccctgcctgctcccgggagcctttgctgactcctggaccccgttgctccggctgagcgtgggc tctttctctaggtctttcctcccaggactctgtgtattcatcctatcgttaaactggattctctacaagagtaataattg cagagtcagccagctctcatcccttttcaggtttcagaaaagacctgtgaacaaaacgccttgagtctgatttagtgtgg caatgccccaagggtcctgttctccctgggtgtcctgcacctggtgcaacgtcggcctggcatctagtgagccatctaaa ggaacgatgatgagtgaatgatttgcctaccccttccagtactaggctggaggtcgtggttagggcccatccctacgcag gacatgcaaagtgggaggcactcctctctctacgtcggcagggggcgctgcacagctgcggggcggggtagcttagacac ggggcgtccggctaaggccggggacccagggtggtgggcggggtgtcccgcccgcctgtggaccccgcgcagtaactgcg aacatttcgctttcattttgggccgagctggaggcggcggggccgtcccggaacggctgcggccgggcaccccgggagtt aatccgaaagcgccgcaagcccccggggccggccgcaccgcacgtgtcaccgagaagctgatgtagagagagacacagaa ggagacagaaagcaagagaccagagtcccgggaaagtcctgccgcgcctcgggacaattataaaaatgtggccccctggg tcagcctcccagccaccgccctcacctgccgcggccacaggtctgcatccagcggctcgccctgtgtccctgcagtgccg gctcagcatgtgtccagcgcgca (SEQ ID NO: 12261) atgtggccccctgggtcagcctcccagccaccgccctcacctgccgcggccacaggtctgcatccagcggctcgccctgt gtccctgcagtgccggctcagcatgtgtccagcgcgcagcctcctccttgtggctaccctggtcctcctggaccacctca gtttggccagaaacctccccgtggccactccagacccaggaatgttcccatgccttcaccactcccaaaacctgctgagg gccgtcagcaacatgctccagaaggccagacaaactctagaattttacccttgcacttctgaagagattgatcatgaaga atcacaaaagataaaaccagcacagtggaggcctgtttaccattggaattaaccaagaatgagagttgcctaaattcca gagagacctctttcataactaatgggagttgcctggcctccagaaagacctcttttatgatggccctgtgccttagtagt atttatgaagacttgaagatgtaccaggtggagttcaagaccatgaatgcaaagcttctgatggatcctaagaggcagat ctttctagatcaaaacatgctggcagttattgatgagctgatgcaggccctgaatttcaacagtgagactgtgccacaaa aatcctcccttgaagaaccggatttttataaaactaaaatcaagctctgcatacttcttcatgctttcagaattcgggca gtgactattgatagagtgatgagctatctgaatgcttcctaaaagcttcttttgcataactggcgctggatttttactga gactttacgttacagttttttttttttaaatttcaaggtgcttttacgaacacatgaataaaatatttgtgtcattttga accttacttgtcttattttatgcatgtatttatttatgggggggcacaaggactcatctgtggtggtgcagccactgtaa ataaattagtgaaactacttcacgtcaatttctgttcagtacactttagtgatggatcggaggaaattaatacatgttta caaaaagcccctcccccagttgttacatatgcctcagagataccagttgtgaaaagtgcaggtgcacttacacacatacg cacacacaccccacaaatggt tcatacgaaaaaacatacctgcaatctgatttgtccacttaattgtatatcttggata cagaacttgtttcactggaaggctaaaaggcaaagtctggggaggcctagaggacacaggggatgggaggaggcgctctg agctggatgtaaggtctccacccacggccagagcacaaggtcggataaccagtgggcctgccggcttggctgcctgggcc ctcccctgccgagacaaacggctggagggaggaagtgtgcggctgggaagctccgctgctctggcccgggtttcccattt cccccttcccgcgctgagacggcgaggaaagttagcccggaaatctgcgcccgcctaaaacccggcctggtcccagccac cgccccaggaacttcccccaccgcaggggcggaggtcgagagcagggatggagaagtggacctgcgcgggtggactccgg ggcgcgggtggactccggggcgcggggggactccgaggagcgggtggactgtggggcgcgggtaccgtctcgcagcgacc tctgtcggcggctctggggatggcccgcatctgtctgcgtgtacctggtatacgtgcaggtacatgttcctgttcacgtg cagactgggcgggggatgggggggtccacaccggtgtacacctttgcatacctcttagcaacttgaaattccaccacgag agatatctttattccgctattcctgtgcatctgcacggagcccctagggccatagatttgtgtgcaaatgaaatgaggat gtagtctgggtgcccaagggggggtgccttgagtgtggttgtctgtatgcctccctgagggtatttcactttctgc ccc atccgcccctatgagcgagtacctatgagcacaggatgtgcacatatttgagtcttattagtggtacacgcagttttatc atctccccaggtctgtgtctgtatgaaatgtgcatgggtgtgtgtgtgcacgcgtgtgttcccactcggggaatgtgggg agaggtgcatggagccaagatgggtggtaaatagtatgtttctgaaattaaaggactaatgtggaggaaggcgccccaga tgtactaaaccctttgccttcatctcatcctctctgacttgggaagaaccaggattttgtttttaagcccttgggcatac agttgttccatcccgacatgaactcagcctcccgtctgaccgccccttggccttccttcttcctcgatctgtggaaccca gggaatctgcctagtgctgtctccaagcaccttggccatgatgtaaacccagagaaattagcatctccatctccttcctt attccccacccaaaagtcatttcctcttagttcattacctgggattttgatgtctatgttccctcctcgttattgataca cacacagagagagacaaacaaaaaaggaacttcttgaaattcccccagaaggttttgagagttgttttcaatgttgcaac aagtcagtttctagtttaagtttccatcagaaaggagtagagtatataagttccagtaccagcaacagcagcagaagaaa caacatctgtttcagggccattggactctccgtcctgcccagagcaaggtaagcacttcccaagcccctacctccctccc ctccctgtgggcctgcaggaattctcagacagcagcattagaaggggccttagagatcaaccatttctcttattttacac acacctaaaactccctacagccgtgcttcatcagcttcgagcagatgagccacccagaaggcagctccagttattaggtc ctagggcctgggtgtagtcaggccctttggaagctccaagtcagagatcaaacacatcctccccactacccacgcctagg gtgactaatgcctgtgggaaaaacaactgaactaaaaagtcccacaggaacctcaaacccagcacatccaaaatggaact tctcaccatctcctccaaactcagtcctcttatacagtaatccctgtaaagctagaacaatctccattccccattctcag ggccttcctctcccgctcacctgaggagctaccaagccttggcccacaagccctctgagagtccctcctgcccaccctgt gttctccatactgaataaggacttggccacaccttgtcaactcttccctctgctctactcctgacccctggatcccccca tcatgcaaattctgccacatctcccgcctaaaacccaggaagactccccactactctcagcacagaaagtacactcctta gtatggcatcccctgccctcatggcatggcccatccagccctccagcctcacaccctgcaaggacacctagacccccacc tccctcaacccttca actgcgcttctgatccctgtttcccctggctagaccctgcgtgccctcccgctggaagcggtc taatgcctgcttgtttttaacactcaggttggggcccctgcctgctcccgggagcctttgctgactcctggaccccgttg ctccggctgagcgtgggctctttctctaggtctttcctcccaggactctgtgtattcatcctatcgttaaactggattct ctacaagagtaataattgcagagtcagccagctctcatcccttttcaggtttcagaaaagacctgtgaacaaaacgcctt gagtctgatttagtgtggcaatgccccaagggtcctgttctccctgggtgtcctgcacctggtgcaacgtcggcctggca tctagtgagccatctaaaggaacgatgatgagtgaatgatttgcctaccccttccagtactaggctggaggtcgtggtta gggcccatccctacgcaggacatgcaaagtgggaggcactcctctctctacgtcggcagggggcgctgcacagctgcggg gcggggtagcttagacacggggcgtccggctaaggccggggacccagggtggtgggcggggtgtcccgcccgcctgtgga ccccgcgcagtaactgcgaacatttcgctttcattttgggccgagctggaggcggcggggccgtcccggaacggctgcgg ccgggcaccccgggagttaatccgaaagcgccgcaagcccccggggccggccgcaccgcacgtgtcaccgagaagctgat gtagagagagacacagaaggaga'cagaaagcaagagaccagagtcccgggaaagtcctgccgcgcctcgggacaatta a aaaatgtggccccctgggtcagcctcccagccaccgccctcacctgccgcggccacaggtctgcatccagcggctcgccc tgtgtccctgcagtgccggctcagcatgtgtccagcgcgca (SEQ ID Nθ:12262) caagcccagagccctgccatttctgtgggctcaggtccctactgctcagccccttcctccctcggcaaggccacaatgaa ccggggagtcccttttaggcacttgcttctggtgctgcaactggcgctcctcccagcagccactcagggaaagaaagtgg tgctgggcaaaaaaggggatacagtggaactgacctgtacagcttcccagaagaagagcatacaattccactggaaaaac tccaaccagataaagattctgggaaatcagggctccttcttaactaaaggtccatccaagctgaatgatcgcgctgactc aagaagaagcctttgggaccaaggaaacttccccctgatcatcaagaatcttaagatagaagactcagatacttacatct gtgaagtggaggaccagaaggaggaggtgcaattgctagtgttcggattgactgccaactctgacacccacctgcttcag gggcagagcctgaccctgaccttggagagcccccctggtagtagcccctcagtgcaatgtaggagtccaaggggtaaaaa catacagggggggaagaccctctccgtgtctcagctggagctccaggatagtggcacctggacatgcactgtcttgcaga accagaagaaggtggagttcaaaatagacatcgtggtgctagctttccagaaggcctccagcatagtctataagaaagag ggggaacaggtggagttctccttcccactcgcctttacagttgaaaagctgacgggcagtggcgagctgtggtggcaggc ggagagggcttcctcctccaagtcttggatcacctttgacctgaagaacaaggaagtgtctgtaaaacgggttacccagg accctaagctccagatgggcaagaagctcccgctccacctcaccctgccccaggccttgcctcagtatgctggctctgga aacctcaccctggcccttgaagcgaaaacaggaaagttgcatcaggaagtgaacctggtggtgatgagagccactcagct ccagaaaaatttgacctgtgaggtgtggggacccacctcccctaagctgatgctgagcttgaaactggagaacaaggagg caaaggtctcgaagcgggagaaggcggtgtgggtgctgaaccctgaggcggggatgtggcagtgtctgctgagtgactcg ggacaggtcctgctggaatccaacatcaaggttctgcccacatggtccaccccggtgcagccaatggccctgattgtgct ggggggcgtcgccggcctcctgcttttcattgggctaggcatcttcttctgtgtcaggtgccggcaccgaaggcgccaag cagagcggatgtctcagatcaagagactcctcagtgagaagaagacctgccagtgccctcaccggtttcagaagacatgt agccccatttgaggcacgaggccaggcagatcccacttgcagcctccccaggtgtctgccccgcgtttcctgcctgcgga ccagatgaatgtagcagatcccacgctctggcctcctgttcgtcctccctacaatttgccattgtttctcctgggttagg ccccggcttcactggttgagtgttgctctctagtttccagaggcttaatcacaccgtcctccacgccatttccttttcct tcaagcctagcccttctctcattatttctctctgaccctctccccactgctcatttggatcc (SEQ ID NO: 12263) ctgccaactctgacacccacctgcttcaggggcagagcctgaccctgaccttggagagcccccctggtagtagcccctca gtgcaatgtaggagtccaaggggtaaaaacatacagggggggaagaccctctccgtgtctcagctggagctccaggatag tggcacctggacatgcactgttttgcagaaccagaagaaggtggagttcaaaatagacatcgtggtgctagctttcc (SEQ ID NO: 12264) tgcagagaacagagaaaggacatctgcgaggaaagttccctgatggctgtcaacaaagtgccacgtctctatggctgtgt acgctgagcacacgattttatcgcgcctatcatatcttggtgcataaacgcacctcacctcggtcaacccttgctccgtc ttatgagacaggctttattatccgcattttatatgaggggaatctgacggtggagagagaattatcttgctcaaggcgac acagcagagcccacaggtggcagaatcccacccgagcccgcttcgacccgcggggtggaaaccacgggcgcccgcccggc tgcgcttccagagctgaactgagaagcgagtcctctccgccctgcggccaccgcccagccccgacccccgccccggcccg atcctcactcgccgccagctccccgcgcccaccccggagttggtggcgcagaggcgggaggcggaggcgggagggcgggc gctggcaccgggaacgcccgagcgccggcagagagcgcggagagcgcgacacgtgcggcccagagcaccggggccacccg gtccccgcaggcccgggaccgcgcccgctggcaggcgacacgtggaagaatacggagttctataccagagttgattgttg atggcacatacttttagaggatgctcattggcatttatgtttataatcacgtggctgttgattaaagcaaaaatagatgc gtgcaagagaggcgatgtgactgtgaagccttcccatgtaattttacttggatccactgtcaatattacatgctctttga agcccagacaaggctgctttcactattccagacgtaacaagttaatcctgtacaagtttgacagaagaatcaattttcac catggccactccctcaattctcaagtcacaggtcttccccttggtacaaccttgtttgtctgcaaactggcctgtatcaa tagtgatgaaattcaaatatgtggagcagagatcttcgttggtgttgctccagaacagcctcaaaatttatcctgcatac agaagggagaacaggggactgtggcctgcacctgggaaagaggacgagacacccacttatacactgagtatactctacag ctaagtggaccaaaaaatttaacctggcagaagcaatgtaaagacatttattgtgactatttggactttggaatcaacct cacccctgaatcacctgaatccaatttcacagccaaggttactgctgtcaatagtcttggaagctcctcttcacttccat ccacattcacattcttggacatagtgaggcctcttcctccgtgggacattagaatcaaatttcaaaaggcttccgtgagc agatgtaccctttattggagagatgagggactggtactgcttaatcgactcaga atcggcccagtaacagcaggctctg gaatatggttaatgttacaaaggccaaaggaagacatgatttgctggatctgaaaccatttacagaatatgaatttcaga tttcctctaagctacatctttataagggaagttggagtgattggagtgaatcattgagagcacaaacaccagaagaagag cctactgggatgttagatgtctggtacatgaaacggcacattgactacagtagacaacagatttctcttttctggaagaa tctgagtgtctcagaggcaagaggaaaaattctccactatcaggtgaccttgcaggagctgacaggagggaaagccatga cacagaacatcacaggacacacctcctggaccacagtcattcctagaaccggaaattgggctgtggctgtgtctgcagca aattcaaaaggcagttctctgcccactcgtattaacataatgaacctgtgtgaggcagggttgctggctcctcgccaggt ctctgcaaactcagagggcatggacaacattctggtgacttggcagcctcccaggaaagatccctctgctgttcaggagt acgtggtggaatggagagagctccatccagggggtgacacacaggtccctctaaactggctacggagtcgaccctacaat gtgtctgctctgatttcagagaacataaaatcctacatctgttatgaaatccgtgtgtatgcactctcaggggatcaagg aggatgcagctccatcctgggtaactctaagcacaaagcaccactgagtggcccccacattaatgccatcacagaggaaa aggggagcattttaatttcatggaacagcattccagtccaggagcaaatgggctgcctcctccattataggatatactgg aaggaacgggactccaactcccagcctcagctctgtgaaattccctacagagtctcccaaaattcacatccaataaacag cctgcagccccgagtgacatatgtcctgtggatgacagctctgacagctgctggtgaaagttcccacggaaatgagaggg aattttgtctgcaaggtaaagccaattggatggcgtttgtggcaccaagcatttgcattgctatcatcatggtgggcatt ttctcaacgcattacttccagcaaaaggtgtttgttctcctagcagccctcagacctcagtggtgtagcagagaaattcc agatccagcaaatagcacttgcgctaagaaatatcccattgcagaggagaagacacagctgcccttggacaggctcctga tagactggcccacgcctgaagatcctgaaccgctggtcatcagtgaagtccttcatcaagtgaccccagttttcagacat cccccctgctccaactggccacaaagggaaaaaggaatccaaggtcatcaggcctctgagaaagacatgatgcacagtgc ctcaagcccaccacctccaagagctctccaagctgagagcagacaactggtggatctgtacaaggtgctggagagcaggg gctccgacccaaagccagaaaacccagcctgtccctggacggtgctcccagcaggtgaccttcccacccatgatggctac ttaccctccaacatagatgacctcccctcacatgaggcacctctcgctgactctctggaagaactggagcctcagcacat ctccctttctgttttcccctcaagttctcttcacccactcaccttctcctgtggtgataagctgactctggatcagttaa agatgaggtgtgactccctcatgctctgagtggtgaggcttcaagccttaaagtcagtgtgccctcaaccagcacagcct gccccaattcccccagcccctgctccagcagctg catctctgggtgccaccatcggtctggctgcagctagaggacagg caagccagctctgggggagtcttaggaactgggagttggtcttcactcagatgcctcatcttgcctttcccagggcctta aaattacatccttcactgtgtggacctagagactccaacttgaattcctagtaactttcttggtatgctggccagaaagg gaaatgaggaggagagtagaaaccacagctcttagtagtaatggcatacagtctagaggaccattcatgcaatgactatt tctaaagcacctgctacacagcaggctgtacacagcagatcagtactgttcaacagaacttcctgagatgatggaaatgt tctacctctgcactcactgtccagtacattagacactaggcacattggctgttaatcacttggaatgtgtttagcttgac tgaggaattaaattttgattgtaaatttaaatcgccacacatggctagtggctactgtattggagtgcacagctctagat ggctcctagattattgagagcctccaaaacaaatcaacctagttctatagatgaagacataaaagacactggtaaacacc aatgtaaaagggcccccaaggtggtcatgactggtctcatttgcagaagtctaagaatgtacctttttctggccgggcgt ggtagctcatgcctgtaatcccagcactttgggaggctga (SEQ ID NO:12265) caagcccagagccctgccatttctgtgggctcaggtccctactgctcagccccttcctccctcggcaaggccacaatgaa ccggggagtcccttttaggcacttgcttctggtgctgcaactggcgctcctcccagcagccactcagggaaagaaagtgg tgctgggcaaaaaaggggatacagtggaactgacctgtacagcttcccagaagaagagcatacaattccactggaaaaac tccaaccagataaagattctgggaaatcagggctccttcttaactaaaggtccatccaagctgaatgatcgcgctgactc aagaagaagcctttgggaccaaggaaacttccccctgatcatcaagaatcttaagatagaagactcagatacttacatct gtgaagtggaggaccagaaggaggaggtgcaattgctagtgttcggattgactgccaactctgacacccacctgcttcag gggcagagcctgaccctgaccttggagagcccccctggtagtagcccctcagtgcaatgtaggagtccaaggggtaaaaa catacagggggggaagaccctctccgtgtctcagctggagctccaggatagtggcacctggacatgcactgtcttgcaga accagaagaaggtggagttcaaaatagacatcgtggtgctagctttccagaaggcctccagcatagtctataagaaagag ggggaacaggtggagttctccttcccactcgcctttacagttgaaaagctgacgggcagtggcgagctgtggtggcaggc ggagagggcttcctcctccaagtcttggatcacctttgacctgaagaacaaggaagtgtctgtaaaacgggttacccagg accctaagctccagatgggcaagaagctcccgctccacctcaccctgccccaggccttgcctcagtatgctggctctgga aacctcaccctggcccttgaagcgaaaacaggaaagttgcatcaggaagtgaacctggtggtgatgagagccactcagct ccagaaaaatttgacctgtgaggtgtggggacccacctcccctaagctgatgctgagcttgaaactggagaacaaggagg caaaggtctcgaagcgggagaaggcggtgtgggtgctgaaccctgaggcggggatgtggcagtgtctgctgagtgactcg ggacaggtcctgctggaatccaacatcaaggttctgcccacatggtccaccccggtgcagccaatggccctgattgtgct ggggggcgtcgccggcctcctgcttttcattgggctaggcatcttcttctgtgtcaggtgccggcaccgaaggcgccaag cagagcggatgtctcagatcaagagactcctcagtgagaagaagacctgccagtgccctcaccggtttcagaagacatgt agccccatttgaggcacgaggccaggcagatcccacttgcagcctccccaggtgtctgccccgcgtttcctgcctgcgga ccagatgaatgtagcagatcccacgctctggcctcctgttcgtcctccctacaatttgccattgtttctcctgggttagg ccccggcttcactggttgagtgttgctctctagtttccagaggcttaatcacaccgtcctccacgccatttccttttcct tcaagcctagcccttctctcattatttctctctgaccctctccccactgctcatttggatccctgccaactctgacaccc acctgcttcaggggcagagcctgaccctgaccttggagagcccccctggtagtagcccctcagtgcaatgtaggagtcca aggggtaaaaacatacagggggggaagaccctctccgtgtctcagctggagctccaggatagtggcacctggacatgcac tgttttgcagaaccagaagaaggtggagttcaaaatagacatcgtggtgctagctttcctgcagagaacagagaaaggac atctgcgaggaaagttccctgatggctgtcaacaaagtgccacgtctctatggctgtgtacgctgagcacacgattttat cgcgcctatcatatcttggtgcataaacgcacctcacctcggtcaacccttgctccgtcttatgagacaggctttattat ccgcattttat tgaggggaatctgacggtggagagagaattatcttgctcaaggcgacacagcagagcccacaggtggc agaatcccacccgagcccgcttcgacccgcggggtggaaaccacgggcgcccgcccggctgcgcttccagagctgaactg agaagcgagtcctctccgccctgcggccaccgcccagccccgacccccgccccggcccgatcctcactcgccgccagctc cccgcgcccaccccggagttggtggcgcagaggcgggaggcggaggcgggagggcgggcgctggcaccgggaacgcccga gcgccggcagagagcgcggagagcgcgacacgtgcggcccagagcaccggggccacccggtccccgcaggcccgggaccg cgcccgctggcaggcgacacgtggaagaatacggagttctataccagagttgattgttgatggcacatacttttagagga tgctcattggcatttatgtttataatcacgtggctgttgattaaagcaaaaatagatgcgtgcaagagaggcgatgtgac tgtgaagccttcccatgtaattttacttggatccactgtcaatattacatgctctttgaagcccagacaaggctgctttc actattccagacgtaacaagttaatcctgtacaagtttgacagaagaatcaattttcaccatggccactccctcaattct caagtcacaggtcttccccttggtacaaccttgtttgtctgcaaactggcctgtatcaatagtgatgaaattcaaatatg tggagcagagatcttcgttggtgttgctccagaacagcctcaaaatttatcctgcatacagaagggagaacaggggactg tggcctgcacctgggaaagaggacgagacacccacttatacactgagtatactctacagctaagtggaccaaaaaattta acctggcagaagcaatgtaaagacatttattgtgactatttggactttggaatcaacctcacccctgaatcacctgaatc caatttcacagccaaggttactgctgtcaatagtcttggaagctcctcttcacttccatccacattcacattcttggaca tagtgaggcctcttcctccgtgggacattagaatcaaatttcaaaaggcttccgtgagcagatgtaccctttattggaga gatgagggactggtactgcttaatcgactcagatatcggcccagtaacagcaggctctggaatatggttaatgttacaaa ggccaaaggaagacatgatttgctggatctgaaaccatttacagaatatgaatttcagatttcctctaagctacatcttt ataagggaagttggagtgattggagtgaatcattgagagcacaaacaccagaagaagagcctactgggatgttagatgtc tggtacatgaaacggcacattgactacagtagacaacagatttctcttttctggaagaatctgagtgtctcagaggcaag aggaaaaattctccactatcaggtgaccttgcaggagctgacaggagggaaagccatgacacagaacatcacaggacaca cctcctggaccacagtcattcctagaaccggaaattgggctgtggctgtgtctgcagcaaattcaaaaggcagttctctg cccactcgtattaacataatgaacctgtgtgaggcagggttgctggctcctcgccaggtctctgcaaactcagagggcat ggacaacattctggtgacttggcagcctcccaggaaagatccctctgctgttcaggagtacgtggtggaatggagagagc tccatccagggggtgacacacaggtccctctaaactggctacggagtcgaccctacaatgtgtctgctctgatttcagag aacataaaatcctacatctgttatgaaatccgtgtgtatgcactctcaggggatcaaggaggatgcagctccatcctggg taactctaagcacaaagcaccactgagtggcccccacattaatgccatcacagaggaaaaggggagcattttaatttcat ggaacagcattccagtccaggagcaaatgggctgcctcctccattataggatatactggaaggaacgggactccaactcc cagcctcagctctgtgaaattccctacagagtctcccaaaattcacatccaataaacagcctgcagccccgagtgacata tgtcctgtggatgacagctctgacagctgctggtgaaagttcccacggaaatgagagggaattttgtctgcaaggtaaag ccaattggatggcgtttgtggcaccaagcatttgcattgctatcatcatggtgggcattttctcaacgcattacttccag caaaaggtgtttgttctcctagcagccctcagacctcagtggtgtagcagagaaattccagatccagcaaatagcacttg cgctaagaaatatcccattgcagaggagaagacacagctgcccttggacaggctcctgatagactggcccacgcctgaag atcctgaaccgctggtcatcagtgaagtccttca caagtgaccccagttttcagacatcccccctgctccaactggcca caaagggaaaaaggaatccaaggtcatcaggcctctgagaaagacatgatgcacagtgcctcaagcccaccacctccaag agctctccaagctgagagcagacaactggtggatctgtacaaggtgctggagagcaggggctccgacccaaagccagaaa acccagcctgtccctggacggtgctcccagcaggtgaccttcccacccatgatggctacttaccctccaacatagatgac ctcccctcacatgaggcacctctcgctgactctctggaagaactggagcctcagcacatctccctttctgttttcccctc aagttctcttcacccactcaccttctcctgtggtgataagctgactctggatcagttaaagatgaggtgtgactccctca tgctctgagtggtgaggcttcaagccttaaagtcagtgtgccctcaaccagcacagcctgccccaattcccccagcccct gctccagcagctgtcatctctgggtgccaccatcggtctggctgcagctagaggacaggcaagccagctctgggggagtc ttaggaactgggagttggtcttcactcagatgcctcatcttgcctttcccagggccttaaaattacatccttcactgtgt ggacctagagactccaacttgaattcctagtaactttcttggtatgctggccagaaagggaaatgaggaggagagtagaa accacagctcttagtagtaatggcatacagtctagaggaccattcatgcaatgactatttctaaagcacctgctacacag caggctgtacacagcagatcagtactgttcaacagaacttcctgagatgatggaaatgttctacctctgcactcactgtc cagtacattagacactaggcacattggctgttaatcacttggaatgtgtttagcttgactgaggaattaaattttgattg taaatttaaatcgccacacatggctagtggctactgtattggagtgcacagctctagatggctcctagattattgagagc ctccaaaacaaatcaacctagttctatagatgaagacataaaagacactggtaaacaccaatgtaaaagggcccccaagg tggtcatgactggtctcatttgcagaagtctaagaatgtacctttttctggccgggcgtggtagctcatgcctgtaatcc cagcactttgggaggctga (SEQ ID NO.-12266) ggatccccgctgacaatctagaaacaagcaacagaccctctgatgtagccatctgtgccgcgcctctccgcaccgcccgc cacgccttggtccctggagaccaccctccagggcaggggctgccgctcggccgggcccgcggggtccctcggcctgacat ggccggtgctggagcggcacgtgcgcgcctcggcccctcggccgctcccgcccctcgccggtgcgcaccggcgctcgggg agccgctggcccgggtgtccagccggcccttgccctgcctggcgctcggaccgccacctttgccgccccctcgccagcct ccgcagcttccagactggccggtctgcgcgcccacccctgcctcccggaccggccaccgccggaggccgcggaggagggc ccggccgcgcagatcccgcttatcgggccccatctcccgttacataaggccacccccctatctccgcgggccatcgccgc cgcaaccgccgcgccagcgccttctcccacgcgcgggggcgcccctgcccaccgctcccggcagggcttttggtggccat gggggataaggggcgttgactcacccgggcggggctccgggagttgcacagaccaaggtagttccccgctccttccccca tcacggagaccctgtgggagatgccgtgggccctctactacagattaggaaacaggcccgtagaggggtcgcgcggccaa gtagcggcactccaggcactgggggccctcgagggaaggggcagacttctgggagtcagagccagcagctgggctgggaa gcttcgagtgtggacagagagggtgggaatgacgttccctgtgggaagagagggtgggcaagcctgggatgcctctgagc gggaatccagcatgccttgtgaggagggtcacaagcacacccttgtgaggaggttgagccccatcgaggacaggacggag ggagcctgagcaggcagagagggggcctggggaggcgctggttcggggaggaagtgggtaggggagaaatcttgacatca acacccaacaggcaaatgccgtggcctctgctgtgggggtttctggaggacttctaggaaaacgagggaagagcaggaaa aggcgacatggctgtagggccaagcccaggagccgccctccacagcactcattctgcagaagggaaatttgaggccccca gacggcaggggttgatcctgcagagactggtgagcaaaggggatcaccccaagccccagtggcactaggaacacttacaa tc ctgacctggactaaggctgccagcctggcccagttaagagtttcccagaaggatggcccatacactttaaattaaag gggccagacacgtgcacactacttccagccactctggaagctgaggtggggggatcgcttgagtctgggagttggaggcc agcctaggcaggcaacatagtgagaccccatctccaaaaaaacaaaacaaaacaaaacaaaaaaacaccaaaaaagctcc cagaaagacctctgaatctttctggatctctcagtggagacctggaaatctgaactttgacaatccctctcacagtgggg ccaaggaggaattaggcaagccaaaagaagtgaactttactcttctattgcctgtttgaattttgtatccaagcaagtgt tacttaagtaatttaagagactggttcatcgaaaaaataaaactccccaaattcccatagctggtagactgtggtcacag ccacagtgcactaagactatctgctcagcacttctggtgacccaaaagggtctgaggacaggagctcagagttgggtcag ctgtccaggtactcagggttgtcacaggcaaaactgctggaactcagggcagcattgcaaatgccacgccgctctcaggg ccccttgcctgccgctggaattaaacccacccagatcttggaaactctgccctggacccttctcaataagtccatgagaa atcaaactctttcctttatgcgacactggattttccacaaagtaaaatcaagatgagtaaagatgtggtttctagatagt gcctgaaaaagcagagaccatggtgtcaggcgtcaccacttgggcctataaaagctgccacaagacgccaaggccacaag ccacccagcctatgcatccgctcctcaatcctctcctgttggcactgggcctcatggcgcttttgttgaccacggtcatt gctctcacttgccttggcggctttgcctccccaggccctgtgcctccctctacagccctcagggagctcattgaggagct ggtcaacatcacccagaaccagaaggtgagtgtcggctagccagggtcctagctatgagggctccagggtgggtgattcc caagatgaggtcatgagcaggctgggcctggtcctaagatgcctgtaggtcaggaaaaatctccatggaccaaggcccgg cccagccatgagggagagaggagctgggctggggggctcagcactgtggatggacctatggaggtgtctggcagactccc cagggactacctgctctcctggcctggccttgtctgccactgccagctcctactcagccattcctgaacagaggacagca gagaagggccagcaccctcccagaaccatgtggcatttgccaactggattttgaccataacaatgcagccattctcccca gcaccatcataggcccgcccttacaggaggattcgttagtagagtccgctccttgccccactagtaacagctcacatgtc tgagcactgcttacaccaggcctggtgcacgtgctttatgtgtcatttcatcactgccagccacctcaagaggcaggtac gatgaacccattctgctaaggttcagtgaggttaagtgacagaggctggattcaagccaggcctggccaacaccagagtg tccatgctcctaactgcagtgttccctcaccatcagaaggcagggcatttaatacaccagatccccaccgcctcccatct gatttgtcttggtcaacagtggcccaggccactcctacttcactcgtccccaccctggcccttcccgcaggcccctgtcc tcctgccctgactatggcaagccttgcatgcagcttgtcccttactagtggtgtcaatttttttctctcagctccaagac cctaaacagtgggacctcacccctatgcctgctgttcaaagcagaaaacgaagctcaggaatgctgaggggctgccaggc ctgcctctgtgccacaccagggatgcttgtggggcctgtgctggggcagacctggcctgggctgccagggcaggcccaca acccctgccagcactctgctcactgtcactttgctcccacaggctccgctctgcaatggcagcatggtatggagcatcaa cctgacagctggcatggtaaggacctttgggtgcagggaggatggggcagaggctccaggccttgggcttatcttctctg agcctcccttccatggctggggttccaagcaagcttcaagtgctctcctccctcccgccataatctggccccttcccgcc caccacccagactcacctgcgccaggcatctcagccccatcttcctgcagactcacaaaaggcagctgcccaagcagggc ctgacccctcggtgtcccctccccacagtactgtgcagccctggaatccctgatcaacgtgtcaggctgcagtgccatcg agaagacccagaggatgctgagcggattctgcccgcacaaggtctcagctggggtaaggcatcccccaccctctcacacc caccctgcaccccctcctgccaaccctgggctcgctgaagggaagctggctgaatatccatggtgtgtgtccacccaggg gtggggccattgtggcagcagggacgtggccttcgggatttacaggatctgggctcaagggctcctaactcctacctggg cctcaatttccacatctgtacagtagaggtactaacagtacccacctcatggggacttccgtgaggactgaatgagacag tccctggaaagcccctggtttgtgcgagtcgtcccggcctctggcgttctactcacgtgctgacctctttgtcctgcagc agttttccagcttgcatgtccgagacaccaaaatcgaggtggcccagtttgtaaaggacctgctcttacatttaaagaaa ctttttcgcgagggacggttcaactgaaacttcgaaagcatcattatttgcagagacaggacctgactattgaagttgca gattcatttttctttctgatgtcaaaaatgtcttgggtaggcgggaaggagggttagggaggggtaaaattccttagctt agacctcagcctgtgctgcccgtcttcagcctagccgacctcagccttccccttgcccagggctcagcctggtgggcctc ctctgtccagggccctgagctcggtggacccagggatgacatgtccctacacccctcccctgccctagagcacactgtag cattacagtgggtgccccccttgccagacatgtggtgggacagggacccacttcacacacaggcaactgaggcagacagc agctcaggcacacttcttcttggtcttatttattattgtgtgttatttaaatgagtgtgtttgtcaccgttggggattgg ggaagactgtggctgctggcacttggagccaagggttcagagactcagggccccagcactaaagcagtggaccccaggag tccctggtaataagtactgtgtacagaattctgctacctcactggggtcctggggcctcggagcctcatccgaggcaggg tcaggagaggggcagaacagccgctcctgtctgccagccagcagccagctctcagccaacgagtaatttattgtttttcc tcgtatttaaatattaaatatgttagcaaagagttaatatatagaagggtaccttgaacactgggggaggggacattgaa caagttgtttcattgactatcaaactgaagccagaaataaagttggtgacagataggcctgattgtatttgtctttcatt ttggcctttggggacactggtctgtggtctgaagactctgaggagctcttcgggaggctggtgggttggaggaggggact gggatggattacagcgagggtagggtgcagtgacctgggctgaatgcaagctagctcccgagggtggggacatggcctga aggaagccccaccttctgtctgctgcaccagcaaggacggagaggcttgggccagactgtcagggttcaaggagggcatc aggagcagacggagacccaggaagtctcacaatcacatctcctgaggactggccagctgtgtctggcaccacccacacat ccatgtctccctcacaacccaggaggccgatgagaactgtgaggctcagaaagcgtgggcggtttgcctaaggtcacgta gctacttcctcactggggtcctggggcctcagagcctcatctgaggtaaaggagcaaagttgggattggggtccaaaatt cactttaactccaaagcccacacacttaaccaccctgcctatttctgtccaaatgtcacctgtcctgaat (SEQ ID NO: 12267) aagccacccagcctatgcatccgctcctcaatcctctcctgttggcactgggcctcatggcgcttttgttgaccacggtc attgctctcacttgccttggcggctttgcctccccaggccctgtgcctccctctacagccctcagggagctcattgagga gctggtcaacatcacccagaaccagaaggctccgctctgcaatggcagcatggtatggagcatcaacctgacagctggca tgtactgtgcagccctggaatccctgatcaacgtgtcaggctgcagtgccatcgagaagacccagaggatgctgagcgga ttctgcccgcacaaggtctcagctgggcagttttccagcttgcatgtccgagacaccaaaatcgaggtggcccagtttgt aaaggacctgctcttacatttaaagaaactttttcgcgagggacggttcaactgaaacttcgaaagcatcattatttgca gagacaggacctgactattgaagttgcagattcatttttctttctgatgtcaaaaatgtcttgggtaggcgggaaggagg gttagggaggggtaaaattccttagcttagacctcagcctgtgctgcccgtcttcagcctagccgacctcagccttcccc ttgcccagggctcagcctggtgggcctcctctgtccagggccctgagctcggtggacccagggatgacatgtccctacac ccctcccctgccctagagcacactgtagcattacagtgggtgccccccttgccagacatgtggtgggacagggacccact tcacacacaggcaactgaggcagacagcagctcaggcacacttcttcttggtcttatttattattgtgtgttatttaaat gagtgtgtttgtcaccgttggggattggggaagactgtggctgctggcacttggagccaagggttcagagactcagggcc ccagcactaaagcagtggaccccaggagtccctggtaataagtactgtgtacagaattctgctacctcactggggtcctg gggcctcggagcctcatccgaggcagggtcaggagaggggcagaacagccgctcctgtctgccagccagcagccagctct cagccaacgagtaatttattgtttttcctcgtatttaaatattaaatatgttagcaaagagttaatatatagaagggtac cttgaacactgggggaggggacattgaacaagttgtttcattgactatcaaactgaagccagaaataaagttggtgacag at (SEQ ID NO:12268) ggatccccgctgacaatctagaaacaagcaacagaccctctgatgtagccatctgtgccgcgcctctccgcaccgcccgc cacgccttggtccctggagaccaccctccagggcaggggctgccgctcggccgggcccgcggggtccctcggcctgacat ggccggtgctggagcggcacgtgcgcgcctcggcccctcggccgctcccgcccctcgccggtgcgcaccggcgctcgggg agccgctggcccgggtgtccagccggcccttgccctgcctggcgctcggaccgccacctttgccgccccctcgccagcct ccgcagcttccagactggccggtctgcgcgcccacccctgcctcccggaccggccaccgccggaggccgcggaggagggc ccggccgcgcagatcccgcttatcgggccccatctcccgttacataaggccacccccctatctccgcgggccatcgccgc cgcaaccgccgcgccagcgccttctcccacgcgcgggggcgcccctgcccaccgctcccggcagggcttttggtggccat gggggataaggggcgttgactcacccgggcggggctccgggagttgcacagaccaaggtagttccccgctccttccccca tcacggagaccctgtgggagatgccgtgggccctctactacagattaggaaacaggcccgtagaggggtcgcgcggccaa gtagcggcactccaggcactgggggccctcgagggaaggggcagacttctgggagtcagagccagcagctgggctgggaa gcttcgagtgtggacagagagggtgggaatgacgttccctgtgggaagagagggtgggcaagcctgggatgcctctgagc gggaatccagcatgccttgtgaggagggtcacaagcacacccttgtgaggaggttgagccccatcgaggacaggacggag ggagcctgagcaggcagagagggggcctggggaggcgctggttcggggaggaagtgggtaggggagaaatcttgacatca acacccaacaggcaaatgccgtggcctctgctgtgggggtttctggaggacttctaggaaaacgagggaagagcaggaaa aggcgacatggctgtagggccaagcccaggagccgccctccacagcactcattctgcagaagggaaatttgaggccccca gacggcaggggttgatcctgcagagactggtgagcaaaggggatcaccccaagccccagtggcactaggaacacttacaa tctctgacctggactaaggctgccagcctggcccagttaagagtttcccagaaggatggcccatacactttaaattaaag gggccagacacgtgcacactacttccagccactctggaagctgaggtggggggatcgcttgagtctgggagttggaggcc agcctaggcaggcaacatagtgagaccccatctccaaaaaaacaaaacaaaacaaaacaaaaaaacaccaaaaaagctcc cagaaagacctctgaatctttctggatctctcagtggagacctggaaatctgaactttgacaatccctctcacagtgggg ccaaggaggaattaggcaagccaaaagaagtgaactttactcttctattgcctgtttgaattttgtatccaagcaagtgt tacttaagtaatttaagagactggttcatcgaaaaaataaaactccccaaattcccatagctggtagactgtggtcacag ccacagtgcactaagactatctgctcagcacttctggtgacccaaaagggtctgaggacaggagctcagagttgggtcag ctgtccaggtactcagggttgtcacaggcaaaactgctggaactcagggcagcattgcaaatgccacgccgctctcaggg ccccttgcctgccgctggaattaaacccacccagatcttggaaactctgccctggacccttctcaataagtccatgagaa atcaaactctttcctttatgcgacactggattttccacaaagtaaaatcaagatgagtaaagatgtggtttctagatagt gcctgaaaaagcagagaccatggtgtcaggcgtcaccacttgggcctataaaagctgccacaagacgccaaggccacaag ccacccagcctatgcatccgctcctcaatcctctcctgttggcactgggcctcatggcgcttttgttgaccacggtcatt gctctcacttgccttggcggctttgcctccccaggccctgtgcctccctctacagccctcagggagctcattgaggagct ggtcaacatcacccagaaccagaaggtgagtgtcggctagccagggtcctagctatgagggctccagggtgggtgattcc caagatgaggtcatgagcaggctgggcctggtcctaagatgcctgtaggtcaggaaaaatctccatggaccaaggcccgg cccagccatgagggagagaggagctgggctggggggctcagcactgtggatggacctatggaggtgtctggcagactccc cagggactacctgctctcctggcctggccttgtctgccactgccagctcctactcagccattcctgaacagaggacagca gagaagggccagcaccctcccagaaccatgtggcatttgccaactggattttgaccataacaatgcagccattctcccca gcaccatcataggcccgcccttacaggaggattcgttagtagagtccgctccttgccccactagtaacagctcacatgtc tgagcactgcttacaccaggcctggtgcacgtgctttatgtgtcatttcatcactgccagccacctcaagaggcaggtac gatgaacccattctgctaaggttcagtgaggttaagtgacagaggctggattcaagccaggcctggccaacaccagagtg tccatgctcctaactgcagtgttccctcaccatcagaaggcagggcatttaatacaccagatccccaccgcctcccatct gatttgtcttggtcaacagtggcccaggccactcctacttcactcgtccccaccctggcccttcccgcaggcccctgtcc tcctgccctgactatggcaagccttgcatgcagcttgtcccttactagtggtgtcaatttttttctctcagctccaagac cctaaacagtgggacctcacccctatgcctgctgttcaaagcagaaaacgaagctcaggaatgctgaggggctgccaggc ctgcctctgtgccacaccagggatgcttgtggggcctgtgctggggcagacctggcctgggctgccagggcaggcccaca acccctgccagcactctgctcactgtcactttgctcccacaggctccgctctgcaatggcagcatggtatggagcatcaa cctgacagctggcatggtaaggacctttgggtgcagggaggatggggcagaggctccaggccttgggcttatcttctctg agcctcccttccatggctggggttccaagcaagcttcaagtgctctcctccctcccgccataatctggccccttcccgcc caccacccagactcacctgcgccaggcatctcagccccatcttcctgcagactcacaaaaggcagctgcccaagcagggc ctgacccctcggtgtcccctccccacagtactgtgcagccctggaatccctgatcaacgtgtcaggctgcagtgcca cg agaagacccagaggatgctgagcggattctgcccgcacaaggtctcagctggggtaaggcatcccccaccctctcacacc caccctgcaccccctcctgccaaccctgggctcgctgaagggaagctggctgaatatccatggtgtgtgtccacccaggg gtggggccattgtggcagcagggacgtggccttcgggatttacaggatctgggctcaagggctcctaactcctacctggg cctcaatttccacatctgtacagtagaggtactaacagtacccacctcatggggacttccgtgaggactgaatgagacag tccctggaaagcccctggtttgtgcgagtcgtcccggcctctggcgttctactcacgtgctgacctctttgtcctgcagc agttttccagcttgcatgtccgagacaccaaaatcgaggtggcccagtttgtaaaggacctgctcttacatttaaagaaa ctttttcgcgagggacggttcaactgaaacttcgaaagcatcattatttgcagagacaggacctgactattgaagttgca gattcatttttctttctgatgtcaaaaatgtcttgggtaggcgggaaggagggttagggaggggtaaaattccttagctt agacctcagcctgtgctgcccgtcttcagcctagccgacctcagccttccccttgcccagggctcagcctggtgggcctc ctctgtccagggccctgagctcggtggacccagggatgacatgtccctacacccctcccctgccctagagcacactgtag cattacagtgggtgccccccttgccagacatgtggtgggacagggacccacttcacacacaggcaactgaggcagacagc agctcaggcacacttcttcttggtcttatttattattgtgtgttatttaaatgagtgtgtttgtcaccgttggggattgg ggaagactgtggctgctggcacttggagccaagggttcagagactcagggccccagcactaaagcagtggaccccaggag tccctggtaataagtactgtgtacagaattctgctacctcactggggtcctggggcctcggagcctcatccgaggcaggg tcaggagaggggcagaacagccgctcctgtctgccagccagcagccagctctcagccaacgagtaatttattgtttttcc tcgtatttaaatattaaatatgttagcaaagagttaatatatagaagggtaccttgaacactgggggaggggacattgaa caagttgtttcattgactatcaaactgaagccagaaataaagttggtgacagataggcctgattgtatttgtctttcatt ttggcctttggggacactggtctgtggtctgaagactctgaggagctcttcgggaggctggtgggttggaggaggggact gggatggattacagcgagggtagggtgcagtgacctgggctgaatgcaagctagctcccgagggtggggacatggcctga ^• aggaagccccaccttctgtctgctgcaccagcaaggacggagaggcttgggccagactgtcagggttcaaggagggcatc aggagcagacggagacccaggaagtctcacaatcacatctcctgaggactggccagctgtgtctggcaccacccacacat ccatgtctccctcacaacccaggaggccgatgagaactgtgaggctcagaaagcgtgggcggtttgcctaaggtcacgta gctacttcctcactggggtcctggggcctcagagcctcatctgaggtaaaggagcaaagttgggattggggtccaaaatt cactttaactccaaagcccacacacttaaccaccctgcctatttctgtccaaatgtcacctgtcctgaataagccaccca gcctatgcatccgctcctcaatcctctcctgttggcactgggcctcatggcgcttttgttgaccacggtcattgctctca cttgccttggcggctttgcctccccaggccctgtgcctccctctacagccctcagggagctcattgaggagctggtcaac atcacccagaaccagaaggctccgctctgcaatggcagcatggtatggagcatcaacctgacagctggcatgtactgtgc agccctggaatccctgatcaacgtgtcaggctgcagtgccatcgagaagacccagaggatgctgagcggattctgcccgc acaaggtctcagctgggcagttttccagcttgcatgtccgagacaccaaaatcgaggtggcccagtttgtaaaggacctg ctcttacatttaaagaaactttttcgcgagggacggttcaactgaaacttcgaaagcatcattatttgcagagacaggac ctgactattgaagttgcagattcatttttctttctgatgtcaaaaatgtcttgggtaggcgggaaggagggttagggagg ggtaaaattccttagcttagacctcagcctgtgctgcccgtcttcagcctagccgacctcagccttccccttgcccaggg ctcagcctggtgggcctcctctgtccagggccctgagctcggtggacccagggatgacatgtccctacacccctcccctg ccctagagcacactgtagcattacagtgggtgccccccttgccagacatgtggtgggacagggacccacttcacacacag gcaactgaggcagacagcagctcaggcacacttcttcttggtcttatttattattgtgtgttatttaaatgagtgtgttt gtcaccgttggggattggggaagactgtggctgctggcacttggagccaagggttcagagactcagggccccagcactaa agcagtggaccccaggagtccctggtaataagtactgtgtacagaattctgctacctcactggggtcctggggcctcgga gcctcatccgaggcagggtcaggagaggggcagaacagccgctcctgtctgccagccagcagccagctctcagccaacga gtaatttattgtttttcctcgtatttaaatattaaatatgttagcaaagagttaatatatagaagggtaccttgaacact gggggaggggacattgaacaagttgtttcattgactatcaaactgaagccagaaataaagttggtgacagat (SEQ ID NO: 12269) ttcggcatccgctcctcaatcctctcctgttggcactgggcctcatggcgcttttgttgaccacggtcattgctctcact tgccttggcggctttgcctccccaggccctgtgcctccctctacagccctcagggagctcattgaggagctggtcaacat cacccagaaccagaaggctccgctctgcaatggcagcatggtatggagcatcaacctgacagctggcatgtactgtgcag ccctggaatccctgatcaacgtgtcaggctgcagtgccatcgagaagacccagaggatgctgagcggattctgcccgcac aaggtctcagctgggcagttttccagcttgcatgtccgagacaccaaaatcgaggtggcccagtttgtaaaggacctgct cttacatttaaagaaactttttcgcgagggacggttcaactgaaacttcgaaagcatcattatttgcagagacaggacct gactattgaagttgcagattcatttttctttctgatgtcaaaaatgtcttgggtaggcgggaaggagggttagggagggg taaaattccttagcttagacctcagcctgtgctgcccgtcttcagcctagccgacctcagccttccccttgcccagggct cagcctggtgggcctcctctgtccagggccctgagctcggtggacccagggatgacatgtccctacacccctcccctgcc ctagagcacactgtagcattacagtgggtgccccccttgccagacatgtggtgggacagggacccacttcacacacaggc aactgaggcagacagcagctcaggcacacttcttcttggtcttatttattattgtgtgttatttaaatgagtgtgtttgt caccgttggggattggggaagactgtggctgctggcacttggagccaagggttcagagactcagggccccagcactaaag cagtggaccccaggagtccctggtaataagtactgtgtacagaattctgctacctcactggggtcctggggcctcggagc ctcatccgaggcagggtcaggagaggggcagaacagccgctcctgtctgccagccagcagccagctctcagccaacgagt aatttattgtttttcctcgtatttaaatattaaatatgttagcaaagagttaatatatagaagggtaccttgaacactgg gggaggggacattgaacaagttgtttcattgactatcaaactgaagccagaaataaagttggtgacagat (SEQ ID NO:12270) tcagcccggccgggctccgaggcgagaggctgcatggagtggccggcgcggctctgcgggctgtgggcgctgctgctctg cgccggcggcgggggcgggggcgggggcgccgcgcctacggaaactcagccacctgtgacaaafttgagtgtctctgttg aaaacctctgcacagtaatatggacatggaatccacccgagggagccagctcaaattgtagtctatggtattttagtcat tttggcgacaaacaagataagaaaatagctccggaaactcgtcgttcaatagaagtacccctgaatgagaggatttgtct gcaagtggggtcccagtgtagcaccaatgagagtgagaagcctagcattttggttgaaaaatgcatctcacccccagaag gtgatcctgagtctgctgtgactgagcttcaatgcatttggcacaacctgagctacatgaagtgttcttggctccctgga aggaataccagtcccgacactaactatactctctactattggcacagaagcctggaaaaaattcatcaatgtgaaaacat ctttagagaaggccaatactttggttgttcctttgatctgaccaaagtgaaggattccagttttgaacaacacagtgtcc aaataatggtcaaggataatgcaggaaaaattaaaccatccttcaatatagtgcctttaacttcccgtgtgaaacctgat cctccacatattaaaaacctctccttccacaatgatgacctatatgtgcaatgggagaatccacagaattttattagcag atgcctattttatgaagtagaagtcaataacagccaaactgagacacataatgttttctacgtccaagaggctaaatgtg agaatccagaatttgagagaaatgtggagaatacatcttgtttcatggtccctggtgttcttcctgatactttgaacaca gtcagaataagagtcaaaacaaataagttatgctatgaggatgacaaactctggagtaattggagccaagaaatgagtat aggtaagaagcgcaattccacactctacataaccatgttactcattgttccagtcatcgtcgcaggtgcaatcatagtac tcctgctttacctaaaaaggctcaagattattatattccctccaattcctgatcctggcaagatttttaaagaaatgttt ggagaccagaatgatgatactctgcactggaagaagtacgacatctatgagaagcaaaccaaggaggaaaccgactctgt agtgctgatagaaaacctgaagaaagcctctcagtgatggagataatttatttttaccttcactgtgaccttgagaagat tcttcccattctccatttgttatctgggaacttattaaatggaaactgaaactactgcaccatttaaaaacaggcagctc ataagagccacaggtctttatgttgagtcgcgcaccgaaaaactaaaaataatgggcgctttggagaagagtgtggagtc attctcattgaattataaaagccagcaggcttcaaactaggggacaaagcaaaaagtgatgatagtggtggagttaatct tatcaagagttgtgacaacttcctgagggatctatacttgctttgtgttctttgtgtcaacatgaacaaattttatttgt aggggaactcatttggggtgcaaatgctaatgtcaaacttgagtcacaaagaacatgtagaaaacaaaatggataaaatc tgatatgtattgtttgggatcctattgaaccatgtttgtggctattaaaactcttttaacagtctgggctgggtccggtg gctcacgcctgtaatcccagcaatttgggagtccgaggcgggcggatcactcgaggtcaggagttccagaccagcctgac caaaatggtgaaacctcctctctactaaaactacaaaaattaactgggtgtggtggcgcgtgcctgtaatcccagctact cgggaagctgaggcaggtgaattgtttgaacctgggaggtggaggttgcagtgagcagagatcacaccactgcactctag cctgggtgacagagcaagactctgtctaaaaaacaaaacaaaacaaaacaaaacaaaaaaacctcttaatattctggagt catcattcccttcgacagcattttcctctgctttgaaagccccagaaatcagtgttggccatgatgacaactacagaaaa accagaggcagcttctttgccaagacctttcaaagccattttaggctgttaggggcagtggaggtagaatgactccttgg gtattagagtttcaaccatgaagtctctaacaatgtattttcttcacctctgctactcaagtagcatttactgtgtcttt ggtttgtgctaggcccccgggtgtgaagcacagaccccttccaggggtttacagtctatttgagactcctcagttcttgc cacttttttttttaatctccaccagtcatttttcagaccttttaactcctcaattccaacactgatttccccttttgcat tctccctccttcccttccttgtagccttttgactttcattggaaattaggatgtaaatctgctcaggagacctggaggag cagaggataattagcatctcaggttaagtgtgagtaatctgagaaacaatgactaattcttgcatattttgtaacttcca tgtgagggttttcagcattgatatttgtgcattttctaaacagagatgaggtggtatcttcacgtagaacattggtattc gcttgagaaaaaaagaatagttgaacctatttctctttctttacaagatgggtccaggattcctcttttctctgccataa atgattaattaaatagcttttgtgtcttacattggtagccagccagccaaggctctgtttatgcttttggggggcatata ttgggttccattctcacctatccacacaacatatccgtata atcccctctactcttacttcccccaaatttaaagaagt atgggaaatgagaggcatttcccccaccccatttctctcctcacacacagactcatattactggtaggaacttgagaact ttatttccaagttgttcaaacatttaccaatcatattaatacaatgatgctatttgcaattcctgctcctaggggagggg agataagaaaccctcactctctacaggtttgggtacaagtggcaacctgcttccatggccgtgtagaagcatggtgccct ggcttctctgaggaagctggggttcatgacaatggcagatgtaaagttattcttgaagtcagattgaggctgggagacag ccgtagtagatgttctactttgttctgctgttctctagaaagaatatttggttttcctgtat ggaatgagattaattcc tttccaggtattttataattctgggaagcaaaacccatgcctccccctagccatttttactgttatcctatttagatggc catgaagaggatgctgtgaaattcccaacaaacattgatgctgacagtcatgcagtctgggagtggggaagtgatctttt gttcccatcctcttcttttagcagtaaaatagctgagggaaaagggagggaaaaggaagttatgggaatacctgtggtgg ttgtgatccctaggtcttgggagctcttggaggtgtctgtatcagtggatttcccatcccctgtgggaaattagtaggct catttactgttttaggtctagcctatgtggattttttcctaacatacctaagcaaacccagtgtcaggatggtaattctt attctttcgttcagttaagtttttcccttcatctgggcactgaagggatatgtgaaacaatgttaacatttttggtagtc ttcaaccagggattgtttctgtttaacttcttataggaaagcttgagtaaaataaatattgtctttttgtatgtcaccc (SEQ ID NO: 12271) tgccaaggctccagcccggccgggctccgaggcgagaggctgcatggagtggccggcgcggctctgcgggctgtgggcgc tgctgctctgcgccggcggcgggggcgggggcgggggcgccgcgcctacggaaactcagccacctgtgacaaatttgagt gtctctgttgaaaacctctgcacagtaatatggacatggaatccacccgagggagccagctcaaattgtagtctatggta ttttagtcattttggcgacaaacaagataagaaaatagctccggaaactcgtcgttcaatagaagtacccctgaatgaga ggatttgtctgcaagtggggtcccagtgtagcaccaatgagagtgagaagcctagcattttggttgaaaaatgcatctca cccccagaaggtgatcctgagtctgctgtgactgagcttcaatgcatttggcacaacctgagctacatgaagtgttcttg gctccctggaaggaataccagtcccgacactaactatactctctactattggcacagaagcctggaaaaaattcatcaat gtgaaaacatctttagagaaggccaatactttggttgttcctttgatctgaccaaagtgaaggattccagttttgaacaa cacagtgtccaaataatggtcaaggataatgcaggaaaaattaaaccatccttcaatatagtgcctttaacttcccgtgt gaaacctgatcctccacatattaaaaacctctccttccacaatgatgacctatatgtgcaatgggagaatccacagaatt ttattagcagatgcctattttatgaagtagaagtcaataacagccaaactgagacacataatgttttctacgtccaagag gctaaatgtgagaatccagaatttgagagaaatgtggagaatacatcttgtttcatggtccctggtgttcttcctgatac tttgaacacagtcagaataagagtcaaaacaaataagttatgctatgaggatgacaaactctggagtaattggagccaag aaatgagtataggtaagaagcgcaattccacactctacataaccatgttactcattgttccagtcatcgtcgcaggtgca atcatagtactcctgctttacctaaaaaggctcaagattattatattccctccaattcctgatcctggcaagatttttaa agaaatgtttggagaccagaatgatgatactctgcactggaagaagtacgacatctatgagaagcaaaccaaggaggaaa ccgactctgtagtgctgatagaaaacctgaagaaagcctctcagtgatggagataatttatttttaccttcactgtgacc ttgagaagattcttcccattctccatttgttatctgggaacttattaaatggaaactgaaactactgcaccatttaaaaa caggcagctcataagagccacaggtctttatgttgagtcgcgcaccgaaaaactaaaaataatgggcgctttggagaaga gtgtggagtcattctcattgaattataaaagccagcaggcttcaaactaggggacaaagcaaaaagtgatgatagtggtg gagttaatcttatcaagagttgtgacaacttcctgagggatctatacttgctttgtgttctttgtgtcaacatgaacaaa ttttatttgtaggggaactcatttggggtgcaaatgctaatgtcaaacttgagtcacaaagaacatgtagaaaacaaaat ggataaaatctgatatgtattgtttgggatcctattgaaccatgtttgtggctattaaaactcttttaacagtctgggct gggtccggtggctcacgcctgtaatcccagcaatttgggagtccgaggcgggcggatcactcgaggtcaggagttccaga ccagcctgaccaaaatggtgaaacctcctctctactaaaactacaaaaattaactgggtgtggtggcgcgtgcctgtaat cccagc actcgggaagctgaggcaggtgaattgtttgaacctgggaggtggaggttgcagtgagcagagatcacaccac tgcactctagcctgggtgacagagcaagactctgtctaaaaaacaaaacaaaacaaaacaaaacaaaaaaacctcttaat attctggagtcatcattcccttcgacagcattttcctctgctttgaaagccccagaaatcagtgttggccatgatgacaa ctacagaaaaaccagaggcagcttctttgccaagacctttcaaagccattttaggctgttaggggcagtggaggtagaat gactccttgggtattagagtttcaaccatgaagtctctaacaatgtattttcttcacctctgctactcaagtagcattta ctgtgtctttggtttgtgctaggcccccgggtgtgaagcacagaccccttccaggggtttacagtctatttgagactcct cagttcttgccacttttttttttaatctccaccagtcatttttcagaccttttaactcctcaattccaacactgatttcc ccttttgcattctccctccttcccttccttgtagccttttgactttcattggaaattaggatgtaaatctgctcaggaga cctggaggagcagaggataattagcatctcaggttaagtgtgagtaatctgagaaacaatgactaattcttgcatatttt gtaacttccatgtgagggttttcagcattgatatttgtgcattttctaaacagagatgaggtggtatcttcacgtagaac attggtattcgcttgagaaaaaaagaatagttgaacctatttctct ctttacaagatgggtccaggattcctcttttc tctgccataaatgattaattaaatagcttttgtgtcttacattggtagccagccagccaaggctctgtttatgcttttgg ggggcatatattgggttccattctcacctatccacacaacatatccg atatatcccctctactcttacttcccccaaat ttaaagaagtatgggaaatgagaggcatttcccccaccccatttctctcctcacacacagactcatattactggtaggaa cttgagaactttatttccaagttgttcaaacatttaccaatcatattaatacaatgatgctatttgcaattcctgctcct aggggaggggagataagaaaccctcactctctacaggtttgggtacaagtggcaacctgcttccatggccgtgtagaagc atggtgccctggcttctctgaggaagctggggttcatgacaatggcagatgtaaagttattcttgaagtcagattgaggc tgggagacagccgtagtagatgttctactttgttctgctgttctctagaaagaatatttggttttcctgtataggaatga gattaattcctttccaggtattttataattctgggaagcaaaacccatgcctccccctagccatttttactgttatccta tttagatggccatgaagaggatgctgtgaaattcccaacaaacattgatgctgacagtcatgcagtctgggagtggggaa gtgatcttttgttcccatcctcttcttttagcagtaaaatagctgagggaaaagggagggaaaaggaagttatgggaata cctgtggtggttgtgatccctaggtcttgggagctcttggaggtgtctgtatcagtggatttcccatcccctgtgggaaa ttagtaggctcatttactgttttaggtctagcctatgtggattttttcctaacatacctaagcaaacccagtgtcaggat ggtaattcttattctttcgttcagttaagtttttcccttcatctgggcactgaagggatatgtgaaacaatgttaacatt tttggtagtcttcaaccagggattgtttctgtttaacttcttataggaaagcttgagtaaaataaatattgtctttttgt atgtcaagcgggccgccaccgcggtggaaactccagctt (SEQ ID NO: 12272) ggatccccgctgacaatctagaaacaagcaacagaccctctgatgtagccatctgtgccgcgcctctccgcaccgcccgc cacgccttggtccctggagaccaccctccagggcaggggctgccgctcggccgggcccgcggggtccctcggcctgacat ggccggtgctggagcggcacgtgcgcgcctcggcccctcggccgctcccgcccctcgccggtgcgcaccggcgctcgggg agccgctggcccgggtgtccagccggcccttgccctgcctggcgctcggaccgccacctttgccgccccctcgccagcct ccgcagcttccagactggccggtctgcgcgcccacccctgcctcccggaccggccaccgccggaggccgcggaggagggc ccggccgcgcagatcccgcttatcgggccccatctcccgttacataaggccacccccctatctccgcgggccatcgccgc cgcaaccgccgcgccagcgccttctcccacgcgcgggggcgcccctgcccaccgctcccggcagggcttttggtggccat gggggataaggggcgttgactcacccgggcggggctccgggagttgcacagaccaaggtagttccccgctccttccccca tcacggagaccctgtgggagatgccgtgggccctctactacagattaggaaacaggcccgtagaggggtcgcgcggccaa gtagcggcactccaggcactgggggccctcgagggaaggggcagacttctgggagtcagagccagcagctgggctgggaa gcttcgagtgtggacagagagggtgggaatgacgttccctgtgggaagagagggtgggcaagcctgggatgcctctgagc gggaatccagcatgccttgtgaggagggtcacaagcacacccttgtgaggaggttgagccccatcgaggacaggacggag ggagcctgagcaggcagagagggggcctggggaggcgctggttcggggaggaagtgggtaggggagaaatcttgacatca acacccaacaggcaaatgccgtggcctctgctgtgggggtttctggaggacttctaggaaaacgagggaagagcaggaaa aggcgacatggctgtagggccaagcccaggagccgccctccacagcactcattctgcagaagggaaatttgaggccccca gacggcaggggttgatcctgcagagactggtgagcaaaggggatcaccccaagccccagtggcactaggaacacttacaa tctctgacctggactaaggctgccagcctggcccagttaagagtttcccagaaggatggcccatacactttaaattaaag gggccagacacgtgcacactacttccagccactctggaagctgaggtggggggatcgcttgagtctgggagttggaggcc agcctaggcaggcaacatagtgagaccccatctccaaaaaaacaaaacaaaacaaaacaaaaaaacaccaaaaaagctcc cagaaagacctctgaatctttctggatctctcagtggagacctggaaatctgaactttgacaatccctctcacagtgggg ccaaggaggaattaggcaagccaaaagaagtgaactttactcttctattgcctgtttgaattttgtatccaagcaagtgt tacttaagtaatttaagagactggttcatcgaaaaaataaaactccccaaattcccatagctggtagactgtggtcacag ccacagtgcactaagactatctgctcagcacttctggtgacccaaaagggtctgaggacaggagctcagagttgggtcag ctgtccaggtactcagggttgtcacaggcaaaactgctggaactcagggcagcattgcaaatgccacgccgctctcaggg ccccttgcctgccgctggaattaaacccacccagatcttggaaactctgccctggacccttctcaataagtccatgagaa atcaaactctttcctttatgcgacactggattttccacaaagtaaaatcaagatgagtaaagatgtggtttctagatagt gcctgaaaaagcagagaccatggtgtcaggcgtcaccacttgggcctataaaagctgccacaagacgccaaggccacaag ccacccagcctatgcatccgctcctcaatcctctcctgttggcactgggcctcatggcgcttttgttgaccacggtcatt gctctcacttgccttggcggctttgcctccccaggccctgtgcctccctctacagccctcagggagctcattgaggagct ggtcaacatcacccagaaccagaaggtgagtgtcggctagccagggtcctagctatgagggctccagggtgggtgattcc caagatgaggtcatgagcaggctgggcctggtcctaagatgcctgtaggtcaggaaaaatctccatggaccaaggcccgg cccagccatgagggagagaggagctgggctggggggctcagcactgtggatggacctatggaggtgtctggcagactccc cagggactacctgctctcctggcctggccttgtctgccactgccagctcctactcagccattcctgaacagaggacagca gagaagggccagcaccctcccagaaccatgtggcatttgccaactggattttgaccataacaatgcagccattctcccca gcaccatcataggcccgcccttacaggaggattcgttagtagagtccgctccttgccccactagtaacagctcacatgtc tgagcactgcttacaccaggcctggtgcacgtgctttatgtgtcatttcatcactgccagccacctcaagaggcaggtac gatgaacccattctgctaaggttcagtgaggttaagtgacagaggctggattcaagccaggcctggccaacaccagagtg tccatgctcctaactgcagtgttccctcaccatcagaaggcagggcatttaatacaccagatccccaccgcctcccatct gatttgtcttggtcaacagtggcccaggccactcctacttcactcgtccccaccctggcccttcccgcaggcccctgtcc tcctgccctgactatggcaagccttgcatgcagcttgtcccttactagtggtgtcaatttttttctctcagctccaagac cctaaacagtgggacctcacccctatgcctgctgttcaaagcagaaaacgaagctcaggaatgctgaggggctgccaggc ctgcctctgtgccacaccagggatgcttgtggggcctgtgctggggcagacctggcctgggctgccagggcaggcccaca acccctgccagcactctgctcactgtcactttgctcccacaggctccgctctgcaatggcagcatggtatggagcatcaa cctgacagctggcatggtaaggacctttgggtgcagggaggatggggcagaggctccaggccttgggcttatcttctctg agcctcccttccatggctggggttccaagcaagcttcaagtgctctcctccctcccgccataatctggccccttcccgcc caccacccagactcacctgcgccaggcatctcagccccatcttcctgcagactcacaaaaggcagctgcccaagcagggc ctgacccctcggtgtcccctccccacagtactgtgcagccctggaatccctgatcaacgtgtcaggctgcagtgccatcg agaagacccagaggatgctgagcggattctgcccgcacaaggtctcagctggggtaaggcatcccccaccctctcacacc caccctgcaccccctcctgccaaccctgggctcgctgaagggaagctggctgaatatccatggtgtgtgtccacccaggg gtggggccattgtggcagcagggacgtggccttcgggatttacaggatctgggctcaagggctcctaactcctacctggg cctcaatttccacatctgtacagtagaggtactaacagtacccacctcatggggacttccgtgaggactgaatgagacag tccctggaaagcccctggtttgtgcgagtcgtcccggcctctggcgttctactcacgtgctgacctctttgtcctgcagc agttttccagcttgcatgtccgagacaccaaaatcgaggtggcccagtttgtaaaggacctgctcttacatttaaagaaa ctttttcgcgagggacggttcaactgaaacttcgaaagcatcattatttgcagagacaggacctgactattgaagttgca gattcatttttctttctgatgtcaaaaatgtcttgggtaggcgggaaggagggttagggaggggtaaaattccttagctt agacctcagcctgtgctgcccgtcttcagcctagccgacctcagccttccccttgcccagggctcagcctggtgggcctc ctctgtccagggccctgagctcggtggacccagggatgacatgtccctacacccctcccctgccctagagcacactgtag cattacagtgggtgccccccttgccagacatgtggtgggacagggacccacttcacacacaggcaactgaggcagacagc agctcaggcacacttcttcttggtcttatttattattgtgtgttatttaaatgagtgtgtttgtcaccgttggggattgg ggaagactgtggctgctggcacttggagccaagggttcagagactcagggccccagcactaaagcagtggaccccaggag tccctggtaataagtactgtgtacagaattctgctacctcactggggtcctggggcctcggagcctcatccgaggcaggg tcaggagaggggcagaacagccgctcctgtctgccagccagcagccagctctcagccaacgagtaatttattgtttttcc tcgtatttaaatattaaatatgttagcaaagagttaatatatagaagggtaccttgaacactgggggaggggacattgaa caagttgtttcattgact tcaaactgaagccagaaataaagttggtgacagataggcctgattgtatttgtctttcatt ttggcctttggggacactggtctgtggtctgaagactctgaggagctcttcgggaggctggtgggttggaggaggggact gggatggattacagcgagggtagggtgcagtgacctgggctgaatgcaagctagctcccgagggtggggacatggcctga aggaagccccaccttctgtctgctgcaccagcaaggacggagaggcttgggccagactgtcagggttcaaggagggcatc aggagcagacggagacccaggaagtctcacaatcacatctcctgaggactggccagctgtgtctggcaccacccacacat ccatgtctccctcacaacccaggaggccgatgagaactgtgaggctcagaaagcgtgggcggtttgcctaaggtcacgta gctacttcctcactggggtcctggggcctcagagcctcatctgaggtaaaggagcaaagttgggattggggtccaaaatt cactttaactccaaagcccacacacttaaccaccctgcctatttctgtccaaatgtcacctgtcctgaat (SEQ ID NO:1227 ) ttcggcatccgctcctcaatcctctcctgttggcactgggcctcatggcgcttttgttgaccacggtcat gctctcact tgccttggcggctttgcctccccaggccctgtgcctccctctacagccctcagggagctcattgaggagctggtcaacat cacccagaaccagaaggctccgctctgcaatggcagcatggtatggagcatcaacctgacagctggcatgtactgtgcag ccctggaatccctgatcaacgtgtcaggctgcagtgccatcgagaagacccagaggatgctgagcggattctgcccgcac aaggtctcagctgggcagttttccagcttgcatgtccgagacaccaaaatcgaggtggcccagtttgtaaaggacctgct cttacatttaaagaaactttttcgcgagggacggttcaactgaaacttcgaaagcatcattatttgcagagacaggacct gactattgaagttgcagattcatttttctttctgatgtcaaaaatgtcttgggtaggcgggaaggagggttagggagggg taaaattccttagcttagacctcagcctgtgctgcccgtcttcagcctagccgacctcagccttccccttgcccagggct cagcctggtgggcctcctctgtccagggccctgagctcggtggacccagggatgacatgtccctacacccctcccctgcc ctagagcacactgtagcattacagtgggtgccccccttgccagacatgtggtgggacagggacccacttcacacacaggc aactgaggcagacagcagctcaggcacacttcttcttggtcttatttattattgtgtgttatttaaatgagtgtgtttgt caccgttggggattggggaagactgtggctgctggcacttggagccaagggttcagagactcagggccccagcactaaag cagtggaccccaggagtccctggtaataagtactgtgtacagaattctgctacctcactggggtcctggggcctcggagc ctcatccgaggcagggtcaggagaggggcagaacagccgctcctgtctgccagccagcagccagctctcagccaacgagt aatttattgtttttcctcgtatttaaatattaaatatgttagcaaagagttaatatatagaagggtaccttgaacactgg gggaggggacattgaacaagttgtttcattgact tcaaactgaagccagaaataaagttggtgacagattcagcccggc cgggctccgaggcgagaggctgcatggagtggccggcgcggctctgcgggctgtgggcgctgctgctctgcgccggcggc gggggcgggggcgggggcgccgcgcctacggaaactcagccacctgtgacaaatttgagtgtctctgttgaaaacctctg cacagtaatatggacatggaatccacccgagggagccagctcaaattgtagtctatggtattttagtcattttggcgaca aacaagataagaaaatagctccggaaactcgtcgttcaatagaagtacccctgaatgagaggatttgtctgcaagtgggg tcccagtgtagcaccaatgagagtgagaagcctagcattttggttgaaaaatgcatctcacccccagaaggtgatcctga gtctgctgtgactgagcttcaatgcatttggcacaacctgagctacatgaagtgttcttggctccctggaaggaatacca gtcccgacactaactatactctctactattggcacagaagcctggaaaaaattcatcaatgtgaaaacatctttagagaa ggccaatactttggttgttcctttgatctgaccaaagtgaaggattccagttttgaacaacacagtgtccaaataatggt caaggataatgcaggaaaaattaaaccatccttcaatatagtgcctttaacttcccgtgtgaaacctgatcctccacata ttaaaaacctctccttccacaatgatgacctatatgtgcaatgggagaatccacagaattttattagcagatgcctattt tatgaagtagaagtcaataacagccaaactgagacacataatgttttctacgtccaagaggctaaatgtgagaatccaga atttgagagaaatgtggagaatacatcttgtttcatggtccctggtgttcttcctgatactttgaacacagtcagaataa gagtcaaaacaaataagttatgctatgaggatgacaaactctggagtaattggagccaagaaatgagtataggtaagaag cgcaattccacactctacataaccatgttactcattgttccagtcatcgtcgcaggtgcaatcatagtactcctgcttta cctaaaaaggctcaagatta tatattccctccaattcctgatcctggcaagatttttaaagaaatgtttggagaccaga atgatga actctgcactggaagaagtacgacatctatgagaagcaaaccaaggaggaaaccgactctgtagtgctgata gaaaacctgaagaaagcctctcagtgatggagataatttatttttaccttcactgtgaccttgagaagattcttcccatt ctccatttgttatctgggaacttattaaatggaaactgaaactactgcaccatttaaaaacaggcagctcataagagcca caggtctttatgttgagtcgcgcaccgaaaaactaaaaataatgggcgctttggagaagagtgtggagtcattctcattg aattataaaagccagcaggcttcaaactaggggacaaagcaaaaagtgatgatagtggtggagttaatcttatcaagagt tgtgacaacttcctgagggatctatacttgctttgtgttctttgtgtcaacatgaacaaattttatttgtaggggaactc atttggggtgcaaatgctaatgtcaaacttgagtcacaaagaacatgtagaaaacaaaatggataaaatctgatatgtat tgtttgggatcctattgaaccatgtttgtggctattaaaactcttttaacagtctgggctgggtccggtggctcacgcct gtaatcccagcaatttgggagtccgaggcgggcggatcactcgaggtcaggagttccagaccagcctgaccaaaatggtg aaacctcctctctactaaaactacaaaaattaactgggtgtggtggcgcgtgcctgtaatcccagctactcgggaagctg aggcaggtgaattgtttgaacctgggaggtggaggttgcagtgagcagagatcacaccactgcactctagcctgggtgac agagcaagactctgtctaaaaaacaaaacaaaacaaaacaaaacaaaaaaacctcttaatattctggagtcatcattccc ttcgacagcattttcctctgctttgaaagccccagaaatcagtgttggccatgatgacaactacagaaaaaccagaggca gcttctttgccaagacctttcaaagccattttaggctgttaggggcagtggaggtagaatgactccttgggtattagagt ttcaaccatgaagtctctaacaatgtattttcttcacctctgctactcaagtagcatttactgtgtctttggtttgtgct aggcccccgggtgtgaagcacagaccccttccaggggtttacagtctatttgagactcctcagttcttgccacttttttt tttaatctccaccagtcatttttcagaccttttaactcctcaattccaacactgatttccccttttgcattctccctcct tcccttccttgtagccttttgactttcattggaaattaggatgtaaatctgctcaggagacctggaggagcagaggataa ttagcatctcaggttaagtgtgagtaatctgagaaacaatgactaattcttgcatattttgtaacttccatgtgagggtt ttcagcattgatatttgtgcattttctaaacagagatgaggtggtatcttcacgtagaacattggtattcgcttgagaaa aaaagaatagttgaacctatttctctttctttacaagatgggtccaggattcctcttttctctgccataaatgattaatt aaatagcttttgtgtcttacattggtagccagccagccaaggctctgtttatgcttttggggggcatatattgggttcca ttctcacctatccacacaacatatccgtatatatcccctctactcttacttcccccaaatttaaagaagtatgggaaatg agaggcatttcccccaccccatttctctcctcacacacagactcatattactggtaggaacttgagaactttatttccaa gttgttcaaacatttaccaatcatattaatacaatgatgctatttgcaattcctgctcctaggggaggggagataagaaa ccctcactctctacaggtttgggtacaagtggcaacctgcttccatggccgtgtagaagcatggtgccctggcttctctg aggaagctggggttcatgacaatggcagatgtaaagtta tcttgaagtcagattgaggctgggagacagccgtagtaga tgttctactttgttctgctgttctctagaaagaatatttggttttcctgtataggaatgagattaattcctttccaggta ttttataattctgggaagcaaaacccatgcctccccctagccatttttactgttatcctatttagatggccatgaagagg atgctgtgaaattcccaacaaacattgatgctgacagtcatgcagtctgggagtggggaagtgatcttttgttcccatcc tcttcttttagcagtaaaatagctgagggaaaagggagggaaaaggaagttatgggaatacctgtggtggttgtgatccc taggtcttgggagctcttggaggtgtctgtatcagtggatttcccatcccctgtgggaaattagtaggctcatttactgt tttaggtctagcctatgtggattttttcctaacatacctaagcaaacccagtgtcaggatggtaattcttattctttcgt tcagttaagtttttcccttcatctgggcactgaagggatatgtgaaacaatgttaacatttttggtagtcttcaaccagg gattgtttctgtttaacttcttataggaaagcttgagtaaaataaatattgtctttttgtatgtcaccctgccaaggctc cagcccggccgggctccgaggcgagaggctgcatggagtggccggcgcggctctgcgggctgtgggcgctgctgctctgc gccggcggcgggggcgggggcgggggcgccgcgcctacggaaactcagccacctgtgacaaatttgagtgtctctgttga aaacctctgcacagtaatatggacatggaatccacccgagggagccagctcaaattgtagtctatggtattttagtcatt ttggcgacaaacaagataagaaaatagctccggaaactcgtcgttcaatagaagtacccctgaatgagaggatttgtctg caagtggggtcccagtgtagcaccaatgagagtgagaagcctagcattttggttgaaaaatgcatctcacccccagaagg tgatcctgagtctgctgtgactgagcttcaatgcatttggcacaacctgagctacatgaagtgttcttggctccctggaa ggaataccagtcccgacactaactatactctctactattggcacagaagcctggaaaaaattcatcaatgtgaaaacatc tttagagaaggccaatactttggttgttcctttgatctgaccaaagtgaaggattccagttttgaacaacacagtgtcca aataatggtcaaggataatgcaggaaaaattaaaccatccttcaatatagtgcctttaacttcccgtgtgaaacctgatc ctccacatattaaaaacctctccttccacaatgatgacctatatgtgcaatgggagaatccacagaattttattagcaga tgcctattttatgaagtagaagtcaataacagccaaactgagacacataatgttttctacgtccaagaggctaaatgtga gaatccagaatttgagagaaatgtggagaatacatcttgtttcatggtccctggtgttcttcctgatactttgaacacag tcagaataagagtcaaaacaaataagttatgctatgaggatgacaaactctggagtaattggagccaagaaatgagtata ggtaagaagcgcaattccacactctacataaccatgttactcattgttccagtcatcgtcgcaggtgcaatcatagtact cctgctttacctaaaaaggctcaagattattatattccctccaattcctgatcctggcaagatttttaaagaaatgtttg gagaccagaatgatgatactctgcactggaagaagtacgacatctatgagaagcaaaccaaggaggaaaccgactctgta gtgctgatagaaaacctgaagaaagcctctcagtgatggagataatttatttttaccttcactgtgaccttgagaagatt cttcccattctccatttgt atctgggaacttattaaatggaaactgaaactactgcaccatttaaaaacaggcagctca taagagccacaggtctttatgttgagtcgcgcaccgaaaaactaaaaataatgggcgctttggagaagagtgtggagtca ttctcattgaattataaaagccagcaggcttcaaactaggggacaaagcaaaaagtgatgatagtggtggagttaatctt atcaagagttgtgacaacttcctgagggatctatacttgctttgtgttctttgtgtcaacatgaacaaattttatttgta ggggaactcatttggggtgcaaatgctaatgtcaaacttgagtcacaaagaacatgtagaaaacaaaatggataaaatct gatatgtattgtttgggatcctattgaaccatgtttgtggctattaaaactcttttaacagtctgggctgggtccggtgg ctcacgcctgtaatcccagcaatttgggagtccgaggcgggcggatcactcgaggtcaggagttccagaccagcctgacc aaaatggtgaaacctcctctctactaaaactacaaaaattaactgggtgtggtggcgcgtgcctgtaatcccagctactc gggaagctgaggcaggtgaattgtttgaacctgggaggtggaggttgcagtgagcagagatcacaccactgcactctagc ctgggtgacagagcaagactctgtctaaaaaacaaaacaaaacaaaacaaaacaaaaaaacctcttaatattctggagtc atcattcccttcgacagcattttcctctgctttgaaagccccagaaatcagtgttggccatgatgacaactacagaaaaa ccagaggcagcttctttgccaagacctttcaaagccattttaggctgttaggggcagtggaggtagaatgactccttggg tattagagtttcaaccatgaagtctctaacaatgtattttcttcacctctgctactcaagtagcatttactgtgtctttg gtttgtgctaggcccccgggtgtgaagcacagaccccttccaggggtttacagtctatttgagactcctcagttcttgcc acttttttttttaatctccaccagtcatttttcagaccttttaactcctcaattccaacactgatttccccttttgcatt ctccctccttcccttccttgtagccttttgactttcattggaaattaggatgtaaatctgctcaggagacctggaggagc agaggataattagcatctcaggttaagtgtgagtaatctgagaaacaatgactaattcttgcatattttgtaacttccat gtgagggttttcagcattgatatttgtgcattttctaaacagagatgaggtggtatcttcacgtagaacattggtattcg cttgagaaaaaaagaatagttgaacctatttctctttctttacaagatgggtccaggattcctcttttctctgccataaa tgattaattaaatagcttttgtgtcttacattggtagccagccagccaaggctctgtttatgcttttggggggcatatat tgggttccattctcaccta ccacacaacatatccgtatatatcccctctactcttacttcccccaaatttaaagaagta tgggaaatgagaggcatttcccccaccccatttctctcctcacacacagactcatattactggtaggaacttgagaactt tatttccaagttgttcaaacatttaccaatcatattaatacaatgatgctatttgcaattcctgctcctaggggagggga gataagaaaccctcactctctacaggtttgggtacaagtggcaacctgcttccatggccgtgtagaagcatggtgccctg gcttctctgaggaagctggggttcatgacaatggcagatgtaaagttattcttgaagtcagattgaggctgggagacagc cgtagtagatgttctactttgttctgctgttctctagaaagaatatttggttttcctgtataggaatgagattaattcct ttccaggtattttataattctgggaagcaaaacccatgcctccccctagccatttttactgttatcctatttagatggcc atgaagaggatgctgtgaaattcccaacaaacattgatgctgacagtcatgcagtctgggagtggggaagtgatcttttg ttcccatcctcttcttttagcagtaaaatagctgagggaaaagggagggaaaaggaagttatgggaatacctgtggtggt tgtgatccctaggtcttgggagctcttggaggtgtctgtatcagtggatttcccatcccctgtgggaaattagtaggctc atttactgttttaggtctagcctatgtggattttttcctaacatacctaagcaaacccagtgtcaggatggtaattctta ttctttcgttcagttaagtttttcccttcatctgggcactgaagggatatgtgaaacaatgttaacatttttggtagtct tcaaccagggattgtttctgtttaacttcttataggaaagcttgagtaaaataaatattgtctttttgtatgtcaagcgg gccgccaccgcggtggaaactccagcttggatccccgctgacaatctagaaacaagcaacagaccctctgatgtagccat ctgtgccgcgcctctccgcaccgcccgccacgccttggtccctggagaccaccctccagggcaggggctgccgctcggcc gggcccgcggggtccctcggcctgacatggccggtgctggagcggcacgtgcgcgcctcggcccctcggccgctcccgcc cctcgccggtgcgcaccggcgctcggggagccgctggcccgggtgtccagccggcccttgccctgcctggcgctcggacc gccacctttgccgccccctcgccagcctccgcagcttccagactggccggtctgcgcgcccacccctgcctcccggaccg gccaccgccggaggccgcggaggagggcccggccgcgcagatcccgctta cgggccccatctcccgttacataaggcca cccccctatctccgcgggccatcgccgccgcaaccgccgcgccagcgccttctcccacgcgcgggggcgcccctgcccac cgctcccggcagggcttttggtggccatgggggataaggggcgttgactcacccgggcggggctccgggagttgcacaga ccaaggtagttccccgctccttcccccatcacggagaccctgtgggagatgccgtgggccctctactacagattaggaaa caggcccgtagaggggtcgcgcggccaagtagcggcactccaggcactgggggccctcgagggaaggggcagacttctgg gagtcagagccagcagctgggctgggaagcttcgagtgtggacagagagggtgggaatgacgttccctgtgggaagagag ggtgggcaagcctgggatgcctctgagcgggaatccagcatgccttgtgaggagggtcacaagcacacccttgtgaggag gttgagccccatcgaggacaggacggagggagcctgagcaggcagagagggggcctggggaggcgctggttcggggagga agtgggtaggggagaaatcttgacatcaacacccaacaggcaaatgccgtggcctctgctgtgggggtttctggaggact tctaggaaaacgagggaagagcaggaaaaggcgacatggctgtagggccaagcccaggagccgccctccacagcactcat tctgcagaagggaaatttgaggcccccagacggcaggggttgatcctgcagagactggtgagcaaaggggatcaccccaa gccccagtggcactaggaacacttacaatctctgacctggactaaggctgccagcctggcccagttaagagtttcccaga aggatggcccatacactttaaattaaaggggccagacacgtgcacactacttccagccactctggaagctgaggtggggg gatcgcttgagtctgggagttggaggccagcctaggcaggcaacatagtgagaccccatctccaaaaaaacaaaacaaaa caaaacaaaaaaacaccaaaaaagctcccagaaagacctctgaatctttctggatctctcagtggagacctggaaatctg aactttgacaatccctctcacagtggggccaaggaggaattaggcaagccaaaagaagtgaactttactcttctattgcc tgtttgaattttgtatccaagcaagtgttacttaagtaatttaagagactggttcatcgaaaaaataaaactccccaaat tcccatagctggtagactgtggtcacagccacagtgcactaagactatctgctcagcacttctggtgacccaaaagggtc tgaggacaggagctcagagttgggtcagctgtccaggtactcagggttgtcacaggcaaaactgctggaactcagggcag cattgcaaatgccacgccgctctcagggccccttgcctgccgctggaattaaacccacccagatcttggaaactctgccc tggacccttctcaataagtccatgagaaatcaaactctttcctttatgcgacactggattttccacaaagtaaaatcaag atgagtaaagatgtggtttctagatagtgcctgaaaaagcagagaccatggtgtcaggcgtcaccacttgggcctataaa agctgccacaagacgccaaggccacaagccacccagcctatgcatccgctcctcaatcctctcctgttggcactgggcct catggcgcttttgttgaccacggtcattgctctcacttgccttggcggctttgcctccccaggccctgtgcctccctcta cagccctcagggagctcattgaggagctggtcaacatcacccagaaccagaaggtgagtgtcggctagccagggtcctag ctatgagggctccagggtgggtgattcccaagatgaggtcatgagcaggctgggcctggtcctaagatgcctgtaggtca ggaaaaatctccatggaccaaggcccggcccagccatgagggagagaggagctgggctggggggctcagcactgtggatg gacctatggaggtgtctggcagactccccagggactacctgctctcctggcctggccttgtctgccactgccagctccta ctcagccattcctgaacagaggacagcagagaagggccagcaccctcccagaaccatgtggcatttgccaactggatttt gaccataacaatgcagccattctccccagcaccatcataggcccgcccttacaggaggattcgttagtagagtccgctcc ttgccccactagtaacagctcacatgtctgagcactgcttacaccaggcctggtgcacgtgctttatgtgtcatttcatc actgccagccacctcaagaggcaggtacgatgaacccattctgctaaggttcagtgaggttaagtgacagaggctggatt caagccaggcctggccaacaccagagtgtccatgctcctaactgcagtgttccctcaccatcagaaggcagggcatttaa tacaccagatccccaccgcctcccatctgatttgtcttggtcaacagtggcccaggccactcctacttcactcgtcccca ccctggcccttcccgcaggcccctgtcctcctgccctgactatggcaagccttgcatgcagcttgtcccttactagtggt gtcaatttttttctctcagctccaagaccctaaacagtgggacctcacccctatgcctgctgttcaaagcagaaaacgaa gctcaggaatgctgaggggctgccaggcctgcctctgtgccacaccagggatgcttgtggggcctgtgctggggcagacc tggcctgggctgccagggcaggcccacaacccctgccagcactctgctcactgtcactttgctcccacaggctccgctct gcaatggcagcatggtatggagcatcaacctgacagctggcatggtaaggacctttgggtgcagggaggatggggcagag gctccaggccttgggcttatcttctctgagcctcccttccatggctggggttccaagcaagcttcaagtgctctcctccc tcccgccataatctggccccttcccgcccaccacccagactcacctgcgccaggcatctcagccccatcttcctgcagac tcacaaaaggcagctgcccaagcagggcctgacccctcggtgtcccctccccacagtactgtgcagccctggaatccctg atcaacgtgtcaggctgcagtgccatcgagaagacccagaggatgctgagcggattctgcccgcacaaggtctcagctgg ggtaaggcatcccccaccctctcacacccaccctgcaccccctcctgccaaccctgggctcgctgaagggaagctggctg aatatccatggtgtgtgtccacccaggggtggggccattgtggcagcagggacgtggccttcgggatttacaggatctgg gctcaagggctcctaactcctacctgggcctcaatttccacatctgtacagtagaggtactaacagtacccacctcatgg ggacttccgtgaggactgaatgagacagtccctggaaagcccctggtttgtgcgagtcgtcccggcctctggcgttctac tcacgtgctgacctctttgtcctgcagcagttttccagcttgcatgtccgagacaccaaaatcgaggtggcccagtttgt aaaggacctgctcttacatttaaagaaactttttcgcgagggacggttcaactgaaacttcgaaagcatcattatttgca gagacaggacctgactattgaagttgcagattcatttttctttctgatgtcaaaaatgtcttgggtaggcgggaaggagg gtt gggaggggtaaaattccttagcttagacctcagcctgtgctgcccgtcttcagcctagccgacctcagccttcccc ttgcccagggctcagcctggtgggcctcctctgtccagggccctgagctcggtggacccagggatgacatgtccctacac ccctcccctgccctagagcacactgtagcattacagtgggtgccccccttgccagacatgtggtgggacagggacccact tcacacacaggcaactgaggcagacagcagctcaggcacacttcttcttggtcttatttattattgtgtgttatttaaat gagtgtgtttgtcaccgttggggattggggaagactgtggctgctggcacttggagccaagggttcagagactcagggcc ccagcactaaagcagtggaccccaggagtccctggtaataagtactgtgtacagaattctgctacctcactggggtcctg gggcctcggagcctcatccgaggcagggtcaggagaggggcagaacagccgctcctgtctgccagccagcagccagctct cagccaacgagtaatttattgtttttcctcgtatttaaatattaaatatgttagcaaagagttaatatatagaagggtac cttgaacactgggggaggggacattgaacaagttgtttcattgactatcaaactgaagccagaaataaagttggtgacag ataggcctgattgtatttgtctttcattttggcctttggggacactggtctgtggtctgaagactctgaggagctcttcg ggaggctggtgggttggaggaggggactgggatggattacagcgagggtagggtgcagtgacctgggctgaatgcaagct agctcccgagggtggggacatggcctgaaggaagccccaccttctgtctgctgcaccagcaaggacggagaggcttgggc cagactgtcagggttcaaggagggcatcaggagcagacggagacccaggaagtctcacaatcacatctcctgaggactgg ccagctgtgtctggcaccacccacacatccatgtctccctcacaacccaggaggccgatgagaactgtgaggctcagaaa gcgtgggcggtttgcctaaggtcacgtagctacttcctcactggggtcctggggcctcagagcctca ctgaggtaaagg agcaaagttgggattggggtccaaaattcactttaactccaaagcccacacacttaaccaccctgcctatttctgtccaa atgtcacctgtcctgaat (SEQ ID NO: 12274) caacaccttcagaaataatcctttgggtgatctcttgtcaatcatttgtgcaggctagagaggcacctgtgaatgataag gctactgagaagcatcattggcctggtcctggcactaccaaagggcaggggaagcgatgcccaaggggctcctgaccagc acatcatcccacgcaaaaacattctccaggtcccttgttccaggcaggaaatccccagctctgagcgccctgccagggct ctgcctagggacaccttttccaggtctagagaatcaaaggagcctccagagcagctaggagggcctgagctgaccaagca agccctgctcacaagacaaatgcagtcaagacctgggtgtattacttgtcttgagctctgaagggcagggaggggtctga gcctcaaatcagacagagaaatgctcaagtcacttctgccaactcactgtgatggcagctacagatgacagcccctctca agactcttcagctcacagacaagccactgacttcatctgtacacacccccatccccaatgcaagcccactgtacacttac aggtataaatgcatttgcaaggccttgcaaaatgccctatgtacgtaaaactgacccacaaaatccaaaattgcaagtgc cagatgccagccaggtcagaacatcctggcttcagcaatgggctgctcagcatgggagccttttatgggccaggcctggc tgggctgccgctcccttcccagcatgacccaacaccaggctctctaggccctggcggaggtgggctcttgaggcccagtc tggcctgatgcttctgtgctcggtgctcctgggtagcaaggcgcttctgtgaccctgggggagctgggtgcttgagcccc aggcccctctggcctcctctcagggccactgtcagtgagggagccctggccaccagcactcaggtcctgtaccctcttgt tcaggtcattgcgctctgtctgcagtgcccggcacagcttctccagccgttggatttttacctgcaggccctccagttct ttatcccggactgttttctcctcagccatctcaagcagggccttgttgctgctctcccaccgggaccggtacatggtggt ttctttctccagcttcttgatcttcttagtcatcttttccatctcctgcttgaatgtggtgaatacctcgctgcttttgg aaagtgtgttctggaactcctcaaacttctctgtgtatagggcaagctgttgcttcaggtgggtctcttgctgcttca c agctcacacatcctctgggactctactgcctctttcaggagaaaatccttctcccgctggtgccgctcttctgcctcctt tagcatctcctgggcctgctggagcttggcatccaccagctgctgttgtaggtccttgtgtttgaagactttgtcgatat gctcctcgcgcagctcatactgctcaatcagcttcttgagcctctcagccagctccatgttctcttggcgcagcttggag ttgcgctcattgtgctgttccatctgcagctgaatgtcattcagtgtcacctggaagtgcgaggtcacctccttgcgctt ctcctcctcctcccgggcccgctgcacaccttcttccttgagggagcggttgtgcccgtgcagctcacggcataggctct caagcttgctgcgggccaggacggcttgctgtgctcaccgcgcaggtggtccttctcttgcaccagctggctctgctttt tctgtaggagcttcatctgcttctgtgaattcc (SEQ ID NO:12275) caacaccttcagaaataatcctttgggtgatctcttgtcaatcatttgtgcaggctagagaggcacctgtgaatgataag gctactgagaagcatcattggcctggtcctggcactaccaaagggcaggggaagcgatgcccaaggggctcctgaccagc acatcatcccacgcaaaaacattctccaggtcccttgttccaggcaggaaatccccagctctgagcgccctgccagggct ctgcctagggacaccttttccaggtctagagaatcaaaggagcctccagagcagctaggagggcctgagctgaccaagca agccctgctcacaagacaaatgcagtcaagacctgggtgtattacttgtcttgagctctgaagggcagggaggggtctga gcctcaaatcagacagagaaatgctcaagtcacttctgccaactcactgtgatggcagctacagatgacagcccctctca agactcttcagctcacagacaagccactgacttcatctgtacacacccccatccccaatgcaagcccactgtacacttac aggtataaatgcatttgcaaggccttgcaaaatgccctatgtacgtaaaactgacccacaaaatccaaaattgcaagtgc cagatgccagccaggtcagaacatcctggcttcagcaatgggctgctcagcatgggagccttttatgggccaggcctggc tgggctgccgctcccttcccagcatgacccaacaccaggctctctaggccctggcggaggtgggctcttgaggcccagtc tggcctgatgcttctgtgctcggtgctcctgggtagcaaggcgcttctgtgaccctgggggagctgggtgcttgagcccc aggcccctctggcctcctctcagggccactgtcagtgagggagccctggccaccagcactcaggtcctgtaccctcttgt tcaggtcattgcgctctgtctgcagtgcccggcacagcttctccagccgttggatttttacctgcaggccctccagttct ttatcccggactgttttctcctcagccatctcaagcagggccttgttgctgctctcccaccgggaccggtacatggtggt ttctttctccagcttcttgatcttcttagtcatcttttccatctcctgcttgaatgtggtgaatacctcgctgcttttgg aaagtgtgttctggaactcctcaaacttctctgtgtatagggcaagctgttgcttcaggtgggtctcttgctgcttcatc agctcacacatcctctgggactctactgcctctttcaggagaaaatccttctcccgctggtgccgctcttctgcctcctt tagcatctcctgggcctgctggagcttggcatccaccagctgctgttgtaggtccttgtgtttgaagactttgtcgatat gctcctcgcgcagctcatactgctcaatcagcttcttgagcctctcagccagctccatgttctcttggcgcagcttggag ttgcgctcattgtgctgttccatctgcagctgaatgtcattcagtgtcacctggaagtgcgaggtcacctccttgcgctt ctcctcctcctcccgggcccgctgcacaccttcttccttgagggagcggttgtgcccgtgcagctcacggcataggctct caagcttgctgcgggccaggacggcttgctgtgctcaccgcgcaggtggtccttctcttgcaccagctggctctgctttt tctgtaggagcttcatctgcttctgtgaattcc (SEQ ID NO: 12276) aaatcctggctgtcatgtacttgctatgggcctagagtagcttacctaaatgctactaaccttcctccataccattattg taaagattaaaggtgatgcatctgttaagtaactaatagagtgcttattaaaaggtaggtgttcaataagtattaattcc ctccctttctttttcttactagtgcacttgtgtttttaatggatcatactttaccctagattgtattgtaggaggcatcg tggatggatggctgctggaaaccccttgccatagccagctcttcttcaatacttaaggatttaccgtggctttgagtaat gagaatttcgaaaccacatttgagaagtatttccatccagtgctacttgtgtttacttctaaacagtcattttctaactg aagctggcattcatgtcttcattttgggatgcagctaatatacccagttggcccaaagcacctaacctatagttatataa tctgactctcagttcagttttactctactaatgccttcatggtattgggaaccatagatttgtgcagctgtttcagtgca gggcttcctaaaacagaagccaactgggtgaatgtaataagtgatttgaaaaaaattgaagatcttattcaatctatgca tattgatgctactttatatacggaaagtgatgttcaccccagttgcaaagtaacagcaatgaagtgctttctcttggagt tacaagttatttcacttgagtccggagatgcaagtattcatgatacagtagaaaatctgatcatcctagcaaacaacagt ttgtcttctaatgggaatgtaacagaatctggatgcaaagaatgtgaggaactggagaaaaaaaatattaaagaattttt gcagagttttgtacatattgtccaaatgttcatcaacacttcttgattgcaattgattctttttaaagtgtttctgttat taacaaacatcactctgctgcttagacataacaaaacactcggcatttcaaatgtgctgtcaaaacaagtttttctgtca agaagatgatcagaccttggatcagatgaactcttagaaatgaaggcagaaaaatgtcattgagtaatatagtgactatg aacttctctcagacttactttactcatttttttaatttattattgaaattgtacatatttgtggaataatgtaaaatgtt gaataaaaatatgtacaagtgttgttttttaaaaaaaaaaaaaaaaaa (SEQ ID NO: 12277) tgtccggcgccccccgggagggaactgggtggccgcaccctcccggctgcggtggctgtcgccccccaccctgcagccag gactcgatggagaatccattccaatatatggccatgtggctctttggagcaatgttccatcatgttccatgctgctgctg acgtcacatggagcacagaaatcaatgttagcagatagccagcccatacaagatcgtattgtattgtaggaggcatcgtg gatggatggctgctggaaaccccttgccatagccagctcttcttcaatacttaaggatttaccgtggctttgagtaatga gaatttcgaaaccacatttgagaagtatttccatccagtgctacttgtgtttacttctaaacagtcattttctaactgaa gctggcattcatgtcttcattttgggctgtttcagtgcagggcttcctaaaacagaagccaactgggtgaatgtaataag tgatttgaaaaaaattgaagatcttattcaatctatgcatattgatgctactttatatacggaaagtgatgttcacccca gttgcaaagtaacagcaatgaagtgctttctcttggagttacaagttatttcacttgagtccggagatgcaagtattcat gatacagtagaaaatctgatcatcctagcaaacaacagtttgtcttctaatgggaatgtaacagaatctggatgcaaaga atgtgaggaactggaggaaaaaaatattaaagaatttttgcagagttttgtacatattgtccaaatgttcatcaacactt cttgattgcaattgattctttttaaagtgtttctgttattaacaaacatcactctgctgcttagacataacaaaacactc ggcatttaaaatgtgctgtcaaaacaagtttttctgtcaagaagatgatcagaccttggatcagatgaactcttagaaat gaaggcagaaaaatgtcattgagtaatatagtgactatgaacttctctcagacttactttactcatttttttaatttatt attgaaattgtacatatttgtggaataatgtaaaatgttgaataaaaatatgtacaagtgttgttttttaagttgcactg atattttacctcttattgcaaaatagcatttgtttaagggtgatagtcaaattatgtattggtggggctgggtaccaatg ct (SEQ ID Nθ:12278) ggcattgtaatcagacagaactggcctcaaatcctggctgtcatgtacttgctatgggcctagagtagcttacctaaatg ctactaaccttcctccataccattattgtaaagattaaaggtgatgcatctgttaagtaactaatagagtgcttattaaa aggtaggtgttcaataagtattaattccctttctttctttttcttactagtgcacttgtgtttttaatggatcatacttt accctagattgtattgtaggaggcatcgtggatggatggctgctggaaaccccttgccatagccagctcttcttcaatac ttaaggatttaccgtggctttgagtaatgagaatttccggtaagaagaaaaatagatgaaaatatcctatggaatttccc ttaaaggtcgtctgaatctcagagtctttgcaataagttacatggttattctccaaagatcttgagatatcacagatgtc tgttcacatttggattgttcttattttgaaaataaataggtttttaaaaactctattgaccatcttgataggctcttctt gtcattataaatgtgttatttcacttatcccactcttttgtgttctctaaatgtctttgtactcactaaattgtgtagtc ttagagggcagggtgtgggtatcattcatctttttgaaaggaagcatgaacaattagtggttaaggtggcagttaacact gctttctgaaactttaaaagcttcgacaacacaaaagaggcaggtgaaagtaccaaaactctggtaagttgtaggataaa tgattttcctaaatcaccaagaaagattattagtcactctcaagatggaatacagtatctgtaattggttccattttatc caatttttcaccaaataatattaatataattcattttcataatttacatgaagttaatataactattgcatctctgttag taatgcatgttattaacctgtgctgtat aaatattttgacctattaaaaaagaaagaaggatgaggaggaggtcaaaga taatataaaaactttaagtggtgacattggtatgtatgtaaattaacaaatatgtcaactttgttaaattatctttgaca tgcatctgcagaaatatctgttaaggaactttgtgcataagagacagagttggaggtgggagagaaagtgaaaaaagata aattatagttttattatttttgataaggggcagtaattatgaaattatgacaaacttacatctttagacctagaaatatg ttgacatgttattttaaacctcactttttaactaaaaaatttaaccatttgtctatgattatatttttcagaaaccacat ttgagaagtatttccatccagtgctacttgtgtttacttctaaacagtcattttctaactgaagctggcattcatgtctt cattttgggggtaattttatctttaggcataaataacattatgttcatggtcatgatgattgtccttggat tattttcc attaaattagtttacgttcagtttgcttatatctctaggtactcagtatctgggggatagaaggcagactacagagattt agagaggtttggtaaacacctaactgagcatttttctacattgtggtaatagtccaaacaagcattatagccctcaaa a aattgggccttttgatatttaactgaacttggaagtataccacttattgatagactacatatttttcatggcaattaaaa gtagatatttagaatttgcttatgttacttttttatctgtccctgacactgactcctcctatcccttgatctttatccta gttcagtttaaaacatttctttctttatttaagccttttgttgtttccttctaataaaattcatatgtttccatgactat taacttttttcttctctcttagatgcagctaatatacccagttggcccaaagcacctaacctatagttatataatctgac tctcagttcagttttactctactaatgccttcatggtattgggaaccatagatttgtgcaggtaattcttcatcataaga cagattagtgttgactatcatgcttctgtgtaagatccatcaggaagtgagtgattatttttcctcaagctctaagcatc attccaatgttacttggtcagtataagtgtattttgtctggatattaaattttaatttttatgaaatttgtgaaagtgag taagtatatgatcattcagcctacactggaatgaagtctgtactgtttatggagaaagctgctgcaagcatagtaagagt gtgagcaacatgaaaggggcatgtttaatgtagtgtaaaaaaaatttactatcaaaatcattacatgaaaatgattatta ctcattttaagaattttacctatttattagacttcaaagtctctgtaaatctctacttaaaggaaactagtaattcattc aaaatcatttattgagcattgccacacatctggcactgcttctatttcattgtgataaattgagccagtttatttataaa gtatgcctacagttaggcttttctctaatccgggttggtgaagcctcaagttatcataaaatgccaaaattgtactatat gctcaatgtttatgttcagttacaaggctgttgaatgcacagaagcaaggataacactgattttttcactggtcagaata aaaattattgattgctcttttgcttatagtattcatcaagatgaataggctccttcaaaatgctttgctctatggttttt ctttcagctgtttcagtgcagggcttcctaaaacagaagccaactgggtgaatgtaataagtgatttgaaaaaaattgaa gatcttattcaagtgagtactcatttttccataaaatgcctggtataactgctatggagtttgtctctctctgtgttttt ctgtctgtcttaaggaaaccacacttgaaacaataatatttttgtagaaatttatgatcttataaagctcaaaaagaagt cttttccttactgttttagaatctaattatctttaaaacgtaattta aagcggcccagacggatgagttctagtctgca caggtgaggtattctcttcctctatctggagaagccagatatcttggtggcacctgcagggagaatggcttgacccaggg aacagctgttgttgcttgtggactaaaggccctcttctcccacctcaagaaaacaggtggcctgacctaaggaagtgatt tttgccatagcaggtaataccagcttcagtggaagtctcgatggcaccaagcataccaaaatagcaccacaaagttctga aaactaaattgtcattggaatcacagcattaaaaaataggttagaacttgcatgctaaatccaaacaacctgactgcatg ttaaaatagaagatttaaataggaccagagtgtcctaacataatagacatgaagccaagatacaattggaaatcacccat tgtaacaagaaataggaaagttacaacttaaatgagaaaat tagtcaacagattacaaaattgaagtggatcagatgtt ggaattctctgacatagatttgaaagcagacattataaaaagtgcttgaaaaagcaattacaaatgcccttgaagcaaat gaaaaactaaatgccttaacaaagaaatagaagatatgaaaggaaccatatagaaattatataactgaaaatataactga aatataaagcaaactgtaaaggctcattagcagaatgaatgacagaggaatgatagttaatttgacaacagaatactaga gagacagttgacttaagaaaaaaaaagcatcactgatcttgacgacagtaacaaaagattcagcattcctatggttagta tcacaggagagtatgagaatacaccaagtaaaagagagagattggttgaattcataacaaaacaccacccatctatacta tctataagcagttcacttctagtacaatgacatacataggttgaaatttaaaaagacagaaaaagatatagcatactata atgggttgaatagtgtccccccaaatttcacatcctcttggaaccttaaaatgtgatcttattttgaaataata ctttg caaatataattaatgaaattaagatgagatcatactagagtagggggggccctaaatccaatgacaagtgtctttattag aaaaggaaaggacacagagtaactcactgggaagaaagccatgtgaagacagaggaagagatcagagtgatgcggctata agccaaggaaggccagagattgccaggatccaccagaaccttggggaagtcaagaaagcattcttctctagactgataca catgcatacattaattataaaaagcagaagtggc atattaacatcaaagttaatgttattaacataaagtagacttcac agaaaataaagttgctataatccagagggatattacaaaatgataaaaaataaatctgtgaggaaaacataatgttctta aatgtatacacatcaaacaacgaagactcaaaatttgtgaaacaaaaaataatagggataaaagagaaatagacaaatcc acaattattcttgaggacttcactgcctcctcctcagtaactaatggaagtactagacagaaaatcagaaagggcataaa aatacaatataaccaaccaacaggatctaatttaatacatagagcactacacccaacaacagcagaatat ctttctttt atcaagactaaatatatactgagccataaaagaaactttaaaaattttttcagaacttaaatcatgcagaatttgttctc aaaccacaatggaatcaaaccagaaatcaagaaattaaatacaacgggcaaatctccaaatgcttggaaattaaatacta tacctctatataatccatgggtcaaagagtaaatctcaaaggatattcataatacatagaatgaaaaaaaatgaaataca gcatatcaagatatatgtgatgtggctaaagcaatactgacaggacattttttaaaatcaaatgaatacattagaaaaaa aggagaattatcaaatcaaaaatctaagttactgcttcaagaaactagaagaagtagagcaaaacaaattcaatacaagc agaacaaagaaaatatttaaatataagagccaaaattaatgaagttgaaatcaagaaaacaatagaaaaaattaatgaaa cataaaactggttatttggaaaatcaatacaattgatctttaattgacagaaataagagagaagacacaaatctcaggaa tgaaatttggggctgtcactacagaatctgcagtcattagaaggataataagaaaaactatgaacaattttatgctcaca aatctgataacttagaggaaatggaccaattcttcagaaaccacaaactaccaaaacataatgaagatgaaatagacaat ccaaacactcatataatcactaaatacattgaattcatcatacacaagctcccaaaaagggaccttcaagcctgctggtt acactgaatcattctatcaaatatttacagaagcattaacaacaattgtacagtctcttctagaaaatagaagaggaagg aacattttccagttgattttaggaggccagtattactgtgatgctaaaaccaaataaagatattactaaaaaagacaact acaaaaatatctcccattaacttagatattaaaatgctctataaaatattaacaaatcgaattcagcaatgtataaaaag aattatacaccatgaccgagtgagatttatttcaggtacacaagtcttgctcaattatttgaaagtcaagcaatgtaatc taccctatcaacaggctaaagaagaaaatcatatgtagaaaaggtatctgataaaatgcaacacctctcatggcctgtgt ccctccctatgcctcctggatttatatgttgaagtactaattgccagtatatcaaaatgtgactgtattttgagataggg tcagttaaaatgaggtcatgagggcaggtcctactgcaatatgactggtatctttagaaaaacagataagggtatagata cacagagatagaaaaccatgtgaagacactgggagaaaatggccacctataagccaaggagggaggactccaaagaaacc aacactgctggtaccctgatttcagacctctagcctcctgaattgtgagaaaataaagttctattatttaagtcaccaag tctgtggtactttttatagcagccctagcagactgatataaacacctattgaagataaaatttcttagaaagtaggtgtg gagaactgcctcaacttggtacaaaacatgttcaaaaagtctagagctaccatacttaatggtgagtacaagactgaatg tttttctgctaggactggaaactaagcagggatatcttctctcaccacttttactcaacataattgtctgagttttctgt tgcttataacagagtacttgaaatgcataatttataaagaaaggaatttatgtcttatggttatgagactgaaaagttca aggttgaggagccacatctggtgagggccttcctgctggtgggggctctctggagtccagaggtgacaaaaagcatcaca tggcgaggggctgaatgtactcatgtgctagctcaggtctctcttcctcttcttataaaactaccggttccctttccgta ataacacattgatactctaatccattcatgagggcagagccattgtgatccaattacctcttaaagccccacctctcaat actgccacattggggattaagtttcaatctgaattttggaggggacattcaaaccacagcaataatattggaagtttagc caaattatgaagcaggagagaaaaaatgtatgagaaaaaaataaataaaaggcacacagattggaaaggaaaattataca tcaccccaagttttttggagagaaagtagtaaaaatgggtatattttgtttagaaagtaatgcaaattaaaaccacaatg acatattattacatgcagctataagcgtatacagaataaaaaatagtgatgatgctaagtaaatataaatgaacaagggt gataatgctggcaaggatgtggagaaactggatcattca acattgctggtgatgatgtaaaatgatacaggcactgtat aaaatagtttggcagcatcctatgaaacaaaacatgcatttgccttacaatccaacaattgtgctcttagacattcatcc ttgataaatgaaaactacgtgcacacaaaaatatgtacatgaatgttcacagagattttttcatgactgccaaaaactgg aaacagatgtgcttcagttggtaaaatctgtgatatatcatgtcagggaatactacagagcaataaaaaggaacaaacta gtgatacccacaagttaggtggatctccagggtattatgatgagtgaaaaaagccagtcttcataaagaaactgtggtac atttataaaatagaatatt tccagtgataaaaagaaataagctatcaagccatgaaaagaaatggagaaaccttcaaag tcatattgttgagtgaaagatggggacgccaatctgaaaaggcttcacactgtatgatcccaactatgacattttgaaaa aggcaaagctatggagacaataaaaagatcagtggttgttaggggtttggagggaaggagaaatggctaggcagagcaca ggctacttttaaagcagtgaaaatattaatatatgatgatgggtggcattatacatttgtcaaaacctgtaaaacataca acacaaataatgagccctaatattctgtacacttaagatcataatagtgattcaccaactataacaaacacaccacacta atgcaagatattaacaatagggaaactggggtggagaacaaaggggtgtataagtctctgtactttctgctagtttttct gtaaacctaaatggctcataaaaatgtctatcaattcttttaaaagctaatttcagaaggttacatatgatatgagtccg tttacataatattcttgaaatgacaaaattataggcatggagagcagagaagtggttgccagaatttagagagattgggt gatgatgaggtatgtatggggagaaaggtgactttggttatgaaagaatagcagcagaatccttgtggtgatgaaact t tttgtgtcttaactgtggtggtggtgatgtgaatctatgcaaatgataaaattgcataaaacttcacacatatgcaagca cacacactgtggcacataaaacttgtgaaatctgaacaaggtgagtgcattgtattaatgtcaattttctgattgtaata ctgtactgtggttatggaagacattaccactgggagaagcttgttgaagggtacacaggatctctctgtatttactctta cagtttcatatgaattttaaattatctcaaaataaaaaaagaattaaaaacaatttaatgttttcagtaggttgttctca taatatttaaagcagggcatagtttttaatattgtctaattttgtttcctttcagtctatgcatattgatgctacttt t atacggaaagtgatgttcacgtgagtatactttttttcaaaattgctatttgtcttgttattaaagtttttaaaagtata tttttgtaacaactaaaatatggtagttttaaaatctaacttttggtgtgtttctataat tatggtccatgagttttat tagtgattattgagatgggacttggggacagatagctacatcaatgctatttttgtaatggtgccaaatcaaaatattaa aagagtcttttccatcaatgtcaaacaagatacattatacgtttttgtgatgcagttgcatcatggtgcaattagatgca aaaatcagattaactgtttcaatttaagagtagccaatatatcagttatttccaatgctgtaatgtatcaccatctgcaa tcatattttccataaattgcttaaaatcattcatgttctgcattttacatgattctctacatttgtcagaaaaagattct aattattctctatgtgagaaaggaaacataacccatgaaacttattagaactgaaaaatggtcttgaacttgtttcatta ataccctgacatttcctaaggaatgtaggatttgtcatgttggtggtggttcttcccttcagtattgttactaaaaccaa gaaatgaatccccaacttcacgtcagggaaaacaaactctatgtcctctctccattattcctcaattagaacttctctta ca agatgactttctaagcattggaaagaaaccatagtcagaaactagaaaaaagagatattcactaaccaattgggtca tgctgctgcacaaagaaattgtctccctcctctggcttcagcatggattctgtttttctttgcattttttgtaaaatgga aagtagtcaattagccaccaaattcagcatcctgaaattgcttttttgcaagaagataactttgcaacccatgggttaga gaaacaaccttagattttagattttagattttagaagtttagattttaaaactgactccaccactttttacttgtgttac cttggagattgctaaacatttctgaagctcatttttattattgctgatatggtgacagtatttgtctttcaatcctaagc agtgactgttgggtttaaggaatattaccagtgctgggcacatgggtgtattccttcattttttttatccattcagtaag catttgtgaagtgtctgcaggctcccaggtactgtgcaaggtatcgaggacacaaagtcaaataatggtcaaatccctag atattccttgtttcctttctttaagttattgttaaagtaaatgttgtggaaaacatatttttgtggcacctaagagagcc ttttctgatttgatctgcctgtaagtggacactagtcctgctttgatttttctaataaatttcttggaattacttctctc cctctggaactttggaacttgaaagaacagt taattagcagctaccactatttaaaatgttaacaacacaatttgattc taaaaattcttacaaataaactgtctatattgatgttttcagactctaaggccagtattattaccctttccacaggggaa atgtgctcggtgagaaaaactggccactatttctgcattttctagtttcatgttcttctgtacaatattgccatccttct tgattgtgttttgttggtttgttttggtttttattttaaagccaaaagaaaaaaaattaagctgcctcctatgtaaaatt tcttaaggatattgtgtatctttataaaatatttggattgactttttgaaaatcaaaattacatcagtatgaaaattaat aatcagaaaaaagtaattgttctttataacttttatttttagcccagttgcaaagtaacagcaatgaagtgctttctctt ggagttacaagttatttcacttgagtccggagatgcaagtattcatgatacagtagaaaatctgatcatcctagcaaaca acagtttgtcttctaatggggtgagttttccaacagttgcttagagttgcatcttatgttttgggcctgatttggagaag tcattcatggacaagcagatcctcctaaggggcaatcaggagaaggagtcctgttccagtggagtggtgtgcaaaagtgg caccatctccagcatgcacacaatgctaaactgttcaatgattgattcagtagacaaacatttacagaataatgccaggt agtgtgcttcagtgctagaattatagttgcaaaccagacagacaggtcactgacctcaaggtgtttattgtcaggtgcag tggatagacattaatctaattacatactcaaatgtctaacatcaataatagtaactcacatttattgagttattactgta tgccagacactattctttgagctttaaattgataattcatttaatcctcatgataaatctgtgagatagttatctttatt tctgtttgaatgttgaagaaattgtagcactgagagcctggatcactcgcttcagttcatacagctagtaaaatggggag ccacaactcttacccgagcagtctgtctgcagagtctgt atctcatgagaagataaatgctttaaaaagataacaatga aaatattaatgattcgagtataatctgggacatcccaggcaacttgagcagtagagggttccaggagagcaaattctagg tactcgtatgataggctggggaatcagctgtgcaatggccctgaagtgcaaagaattagggctttcatggcaaaacacca gtggccaaagcaaggtagagagaaagcagttttgcaacaaagaggcataatcaaattagttcatttcataaatacttttt agccctcaggagacagtatgaaaaaatacccataatccctgctgttaaagagggaggaaacagaaataaaccaagcactc agcaaatgagtaataagttagttatttatgaagtccagtggtgaaaaaggacacagggtaggggcactggggctccagtt agggtaggctgagctaataagctgccatttgacaaagatgtgagagaatgagccttaagggtatctagggacatatgttt aggcagagacaactgaaagtgcaaaggccctaagcttgtgtgggtggacaccttgacttttctctaaaaatacaagactg ctttaggtctttgcttcagtgtcaccttctcagtgatttacctatttacagttgcaatcccttccctatctgagcactcc ctgtccccttctctgcgtgtcccatatctggaatatgatatattttatgtaatgggtattgtctgtttttccctactaga atgtcagcttaaaatggacaagtgtttttgttttttattagtactatatccaaattcccagaacagtgtctcatatatat taaatactttacatatgtatgaaatgaatttattaaggtttataatactcttatgatgttatctccatcttattggtgga aagagtgagccacgcaacaggtaactcatggcaaaataaatgatgagctctttaatgtgaatgttgatagtcatcctcat catgacagagtgtgacatacgtgctggaatgcgtgggcaggactgcacagtcagaagacctggatgggaagaatttcagt tgattatgtcagttgagatgagtcaatatctctgtcttcctatctgacatgattattttcaggatcaaataggacagcat tatatgaaatatgacagtgcttggcatagaggatgtgcttgataaatgtcgctgattctgaattccaaatagttaatgga tataaaatctaatttttatttttgctggcacagccttcatggttcagatgatctctaaaaagtttattcttaattgctac atttggaacattctagttatccatgagactgtgtttgaagtacaacaatttgtggtattcacctaaatggctcagttcaa ccaatgggtgattacagtgtgtcaggccctgtgctaaatgctagggaaacaaacatactggctctgaccttctggcagag agcttagagaatagtattacagtataaaaagagtaaaacttcataatatgaatagaatacatgacatattgtgagagagg tctaaataaggggttctgagatgtaaagatgggacattgagtccagccctaggagcccaggggttcagagaagcctccct aaaagagtacctgaataatcttaagtgcgagtagcagcagctaaaataggaatgaatgtaacagagagaaaagcaaaggc agagaggcatctaatagtatgctgtgcatggcaaggaaagccagatgctcactcagtgtttctagggcataacattgagg caagggggatatgtgaaataaataggtaaggaacagctcatgaagagcctgtgtgctatgcagggaggcatggtctttat gctagaagcagatgataggaaaccattgaagggctcaaagcaggaactccgtggtctgatagacacagcttatttttctc aatgtccttaacccattattggaaaaataaacatatatcaaatctccctgttctctttcctcgtagttcttcctaatatg ctatttatttgctaaagctttcatatctcaagacctcaccatatggttcaaacgatatgatattcccattcccatgaatg tatatttaatttaattataaattgccaatttaatctctctctatattttgcagaatgtaacagaatctggatgcaaagaa tgtgaggaactggaggaaaaaaatattaaagaatttttgcagagttttgtacatattgtccaaatgttcatcaacacttc ttgattgcaattgattctttttaaagtgtttctgttattaacaaacatcactctgctgcttagacataacaaaacactcg gcatttcaaatgtgctgtcaaaacaagtttttctgtcaagaagatgatcagaccttggatcagatgaactcttagaaatg aaggcagaaaaatgtcattgagtaatatagtgactatgaacttctctcagacttactttactcatttttttaatttatta ttgaaattgtacatatttgtggaataatgtaaaatgttgaataaaaatatgtacaagtgttgttttttaagttgcactga tattttacctcttattgcaaaatagcatttgtttaagggtgatagtcaaattatgtattggtggggctgggtaccaatgc tgcaggtcaacagctatgctggtaggctcctgccagtgtggaaccactgactactggctctcattgacttccttactaag ca agcaaacagaggaagaatttgttatcagtaagaaaaagaagaactatatgtgaatcctcttctttatactgtaattt agttattgatgtataaagcaactgttatgaaataaagaaattgcaataactggcatataatgtccatcagtaaatcttgg tggtggtggcaataataaacttctactgataggtagaatggtgtgcaagcttgtccaatcacggattgcaggccacatgc ggcccaggacaactttgaatgtggcccaacacaaattcataaactttcatacatctcgtttttagctcatcagctatcat tagcggtagtgtatttaaagtgtggcccaagacaattcttcttattccaatgtggcccagggaaatcaaaagattggatg cccctggtatagaaaactaatagtgacagtgttcatatttcatgctttcccaaatacaggtattttattttcacattctt tttgccatgtttatataataataaagaaaaaccctgttgatttgttggagccattgttatctgacagaaaataattgttt atattttttgcactacactgtctaaaattagcaagctctcttctaatggaactgtaagaaagatgaaatatttttgtttt attataaatttatttcaccttaattctggtaatactcactgagtgactgtggggtgggaaatgatctcttaagaatttga tttctttctattccatagtacaaactcgttctctgttgaaacattcttctatcaccccagtgccctatccatgtacatgt gttcttattgctctagtcaaacggtgcttataaatatctttcagaaagcttaggagaaatctgtatcctatttgacttcc aataatca (SEQ ID NO: 12279) cggattgggatcggacctacttgattcacttctgggaaatcaaggatctacgtaccatggattttcaggtgcagattttc agcttcctgctaatcagtgcctcagtcataatgtctagagccaactgggtgaatgtaataagtgatttgaaaaaaattga agatcttattcaatctatgcatattgatgctactttatatacggaaagtgatgttcaccccagttgcaaagtaacagcaa tgaagtgctttctcttggagttacaagttatttcacttgagtccggagatgcaagtattcatgatacagtagaaaatctg atcatcctagcaaacaacagtttgtcttctaatgggaatgtaacagaatctggatgcaaagaatgtgaggaactggagga aaaaaatattaaagaatttttgcagagttttgtacatattgtccaaatgttcatcaacacttcttgattgcaattgattc ctcgag (SEQ ID NO:12280) aaatcctggctgtcatgtacttgctatgggcctagagtagcttacctaaatgctactaaccttcctccataccattattg taaagattaaaggtgatgcatctgttaagtaactaatagagtgcttattaaaaggtaggtgttcaataagtattaattcc ctccctttctttttcttactagtgcacttgtgtttttaatgga catactttaccctagattgtattgtaggaggcatcg tggatggatggctgctggaaaccccttgccatagccagctcttcttcaatacttaaggatttaccgtggctttgagtaat gagaatttcgaaaccacatttgagaagtatttccatccagtgctacttgtgtttacttctaaacagtcattttctaactg aagctggcattcatgtcttcattttgggatgcagctaatatacccagttggcccaaagcacctaacctatagttatataa tctgactctcagttcagttttactctactaatgccttcatggtattgggaaccatagatttgtgcagctgtttcagtgca gggcttcctaaaacagaagccaactgggtgaatgtaataagtgatttgaaaaaaattgaagatcttattcaatctatgca attgatgctactttatatacggaaagtgatgttcaccccagttgcaaagtaacagcaatgaagtgctttctcttggagt tacaagttatttcacttgagtccggagatgcaagtattcatgatacagtagaaaatctgatcatcctagcaaacaacagt ttgtcttctaatgggaatgtaacagaatctggatgcaaagaatgtgaggaactggagaaaaaaaatattaaagaattttt gcagagttttgtacatattgtccaaatgttcatcaacacttcttgattgcaattgattctttttaaagtgtttctgttat taacaaacatcactctgctgcttagacataacaaaacactcggcatttcaaatgtgctgtcaaaacaagtttttctgtca agaagatgatcagaccttggatcagatgaactcttagaaatgaaggcagaaaaatgtcattgagtaatatagtgactatg aacttctctcagacttactttactcatttttttaatttattattgaaattgtacatatttgtggaataatgtaaaatgtt gaataaaaatatgtacaagtgttgttttttaaaaaaaaaaaaaaaaaatgtccggcgccccccgggagggaactgggtgg ccgcaccctcccggctgcggtggctgtcgccccccaccctgcagccaggactcgatggagaatccattccaatatatggc catgtggctctttggagcaatgttccatcatgttccatgctgctgctgacgtcacatggagcacagaaatcaatgttagc agatagccagcccatacaagatcgtattgtattgtaggaggcatcgtggatggatggctgctggaaaccccttgccatag ccagctcttcttcaatacttaaggatttaccgtggctttgagtaatgagaatttcgaaaccacatttgagaagtatttcc atccagtgctacttgtgtttacttctaaacagtcattttctaactgaagctggcattcatgtcttcattttgggctgttt cagtgcagggcttcctaaaacagaagccaactgggtgaatgtaataagtgatttgaaaaaaattgaagatcttattcaat ctatgcatattgatgctactttatatacggaaagtgatgttcaccccagttgcaaagtaacagcaatgaagtgctttctc ttggagttacaagttatttcacttgagtccggagatgcaagtattcatgatacagtagaaaatctgatcatcctagcaaa caacagtttgtcttctaatgggaatgtaacagaatctggatgcaaagaatgtgaggaactggaggaaaaaaatattaaag aatttttgcagagttttgtacatattgtccaaatgttcatcaacacttcttgattgcaattgattctttttaaagtgttt ctgttattaacaaacatcactctgctgcttagacataacaaaacactcggcatttaaaatgtgctgtcaaaacaagtttt tctgtcaagaagatgatcagaccttggatcagatgaactcttagaaatgaaggcagaaaaatgtcattgagtaatatagt gactatgaacttctctcagacttactttactcatttttttaatttattattgaaattgtacatatttgtggaataatgta aaatgttgaataaaaatatgtacaagtgttgttttttaagttgcactgatattttacctcttattgcaaaatagcatttg tttaagggtgatagtcaaattatgtattggtggggctgggtaccaatgctggcattgtaatcagacagaactggcctcaa atcctggctgtcatgtacttgctatgggcctagagtagcttacctaaatgctactaaccttcctccataccattattgta aagattaaaggtgatgcatctgttaagtaactaatagagtgcttattaaaaggtaggtgttcaataagtattaattccct ttctttctttttcttactagtgcacttgtgtttttaatggatcatactttaccctagattgtattgtaggaggcatcgtg gatggatggctgctggaaaccccttgccatagccagctcttcttcaatacttaaggatttaccgtggctttgagtaatga gaatttccggtaagaagaaaaatagatgaaaatatcctatggaatttcccttaaaggtcgtctgaatctcagagtctttg caataagttacatggttattctccaaagatcttgagatatcacagatgtctgttcacatttggattgttcttattttgaa aataaataggtttttaaaaactctattgaccatcttgataggctcttcttgtcattataaatgtgttatttcacttatcc cactcttttgtgttctctaaatgtctttgtactcactaaattgtgtagtcttagagggcagggtgtgggtatcattcatc tttttgaaaggaagcatgaacaattagtggttaaggtggcagttaacactgctttctgaaactttaaaagcttcgacaac acaaaagaggcaggtgaaagtaccaaaactctggtaagttgtaggataaatgattttcctaaatcaccaagaaagattat tagtcactctcaagatggaatacagtatctgtaattggttccattttatccaatttttcaccaaataatattaatataat tcattttcataatttacatgaagttaatataactattgcatctctgttagtaatgcatgttattaacctgtgctgtataa aatattttgacctattaaaaaagaaagaaggatgaggaggaggtcaaagataa ataaaaactttaagtggtgacattgg tatgtatgtaaattaacaaatatgtcaactttgttaaattatctttgacatgcatctgcagaaatatctgttaaggaact ttgtgcataagagacagagttggaggtgggagagaaagtgaaaaaagataaattatagttttattatttttgataagggg cagtaattatgaaattatgacaaacttacatctttagacctagaaatatgttgacatgttattttaaacctcacttttta actaaaaaatttaaccatttgtctatgattatatttttcagaaaccacatttgagaagtatttccatccagtgctacttg tgtttacttctaaacagtcattttctaactgaagctggcattcatgtcttcattttgggggtaattttatctttaggcat aaataacattatgttcatggtcatgatgattgtccttggatatattttccattaaattagtttacgttcagtttgcttat atctctaggtactcagtatctgggggatagaaggcagactacagagatttagagaggtttggtaaacacctaactgagca tttttctacattgtggtaatagtccaaaσaagcattatagccctcaaataaattgggccttttgatatttaactgaactt ggaagtataccacttattgatagactacatatttttcatggcaattaaaagtagatatttagaatttgcttatgttactt ttttatctgtccctgacactgactcctcctatcccttgatctttatcctagttcagtttaaaacatttctttctttattt aagccttttgttgtttccttctaataaaattca atgtttccatgactattaacttttttcttctctcttagatgcagct aatatacccagttggcccaaagcacctaacctatagttatataatctgactctcagttcagttttactctactaatgcct tcatggtattgggaaccatagatttgtgcaggtaattcttcatcataagacagattagtgttgactatcatgcttctgtg taagatccatcaggaagtgagtgattatttttcctcaagctctaagcatcattccaatgttacttggtcagtataagtgt attttgtctggatattaaattttaatttttatgaaatttgtgaaagtgagtaagtatatgatcattcagcctacactgga atgaagtctgtactgtttatggagaaagctgctgcaagcatagtaagagtgtgagcaacatgaaaggggcatgtttaatg tagtgtaaaaaaaatttactatcaaaatcattacatgaaaatgattattactcattttaagaattttacctatttattag acttcaaagtctctgtaaatctctacttaaaggaaactagtaattcattcaaaatcatttattgagcattgccacacatc tggcactgcttctatttcattgtgataaattgagccagtttatttataaagtatgcctacagttaggcttttctctaatc cgggttggtgaagcctcaagttatcataaaatgccaaaattgtactatatgctcaatgtttatgttcagttacaaggctg ttgaatgcacagaagcaaggataacactgattttttcactggtcagaataaaaattattgattgctcttttgcttatagt attcatcaagatgaataggctccttcaaaatgctttgctctatggtttttctttcagctgtttcagtgcagggcttccta aaacagaagccaactgggtgaatgtaataagtgatttgaaaaaaattgaagatcttattcaagtgagtactcatttttcc ataaaatgcctggtataactgctatggagtttgtctctctctgtgtttttctgtctgtcttaaggaaaccacacttgaaa caataatatttttgtagaaatttatgatcttataaagctcaaaaagaagtcttttccttactgttttagaatctaattat ctttaaaacgtaatttataagcggcccagacggatgagttctagtctgcacaggtgaggtattctcttcctctatctgga gaagccagatatcttggtggcacctgcagggagaatggcttgacccagggaacagctgttgttgcttgtggactaaaggc cctcttctcccacctcaagaaaacaggtggcctgacctaaggaagtgatttttgccatagcaggtaataccagcttcagt ggaagtctcgatggcaccaagcataccaaaatagcaccacaaagttctgaaaactaaattgtcattggaatcacagcatt aaaaaataggttagaacttgcatgctaaatccaaacaacctgactgcatgttaaaatagaagatttaaataggaccagag tgtcctaacataatagacatgaagccaagatacaattggaaatcacccattgtaacaagaaataggaaagttacaactta aatgagaaaatatagtcaacagattacaaaattgaagtggatcagatgttggaattctctgacatagatttgaaagcaga cattataaaaagtgcttgaaaaagcaattacaaatgcccttgaagcaaatgaaaaactaaatgccttaacaaagaaatag aagatatgaaaggaaccatatagaaattatataactgaaaatataactgaaatataaagcaaactgtaaaggctcattag cagaatgaatgacagaggaatgatagttaatttgacaacagaatactagagagacagttgacttaagaaaaaaaaagcat cactgatcttgacgacagtaacaaaagattcagcattcctatggttagtatcacaggagagtatgagaatacaccaagta aaagagagagattggttgaattcataacaaaacaccacccatctatactatctataagcagttcacttctagtacaatga catacataggttgaaatttaaaaagacagaaaaagatatagcatactataatgggttgaatagtgtccccccaaatttca catcctcttggaaccttaaaatgtgatcttattttgaaataatatctttgcaaata aattaatgaaattaagatgagat catactagagtagggggggccctaaatccaatgacaagtgtctttattagaaaaggaaaggacacagagtaactcactgg gaagaaagccatgtgaagacagaggaagagatcagagtgatgcggctataagccaaggaaggccagagattgccaggatc caccagaaccttggggaagtcaagaaagcattcttctctagactgatacacatgcatacattaattataaaaagcagaag tggctatattaacatcaaagttaatgttattaacataaagtagacttcacagaaaataaagttgctataatccagaggga tattacaaaatgataaaaaataaatctgtgaggaaaacataatgttcttaaatgtatacacatcaaacaacgaagactca aaatttgtgaaacaaaaaataatagggataaaagagaaatagacaaatccacaattattcttgaggacttcactgcctcc tcctcagtaactaatggaagtactagacagaaaatcagaaagggcataaaaatacaatataaccaaccaacaggatctaa tttaatacatagagcactacacccaacaacagcagaatatactttcttttatcaagactaaatatatactgagccataaa agaaactttaaaaattttttcagaacttaaatcatgcagaatttgttctcaaaccacaatggaatcaaaccagaaatcaa gaaattaaatacaacgggcaaatctccaaatgcttggaaattaaatactatacctctatataatccatgggtcaaagagt aaatctcaaaggatattcataatacatagaatgaaaaaaaatgaaatacagcatatcaagatatatgtgatgtggctaaa gcaatactgacaggacattttttaaaatcaaatgaatacattagaaaaaaaggagaattatcaaatcaaaaatctaagtt actgcttcaagaaactagaagaagtagagcaaaacaaattcaatacaagcagaacaaagaaaatatttaaatataagagc caaaattaatgaagttgaaatcaagaaaacaatagaaaaaattaatgaaacataaaactggttatttggaaaatcaatac aattgatctttaattgacagaaataagagagaagacacaaatctcaggaatgaaatttggggctgtcactacagaatctg cagtcattagaaggataataagaaaaactatgaacaattttatgctcacaaatctgataacttagaggaaatggaccaat tcttcagaaaccacaaactaccaaaacataatgaagatgaaatagacaatccaaacactcatataatcactaaatacatt gaattcatcatacacaagctcccaaaaagggaccttcaagcctgctggttacactgaatcattctatcaaatatttacag aagcattaacaacaattgtacagtctcttctagaaaatagaagaggaaggaacattttccagttgattttaggaggccag tattactgtgatgctaaaaccaaataaagatattactaaaaaagacaactacaaaaat tctcccattaacttagatatt aaaatgctctataaaatattaacaaatcgaattcagcaatgtataaaaagaattatacaccatgaccgagtgagatt at ttcaggtacacaagtcttgctcaattatttgaaagtcaagcaatgtaatctaccctatcaacaggctaaagaagaaaatc atatgtagaaaaggtatctgataaaatgcaacacctctcatggcctgtgtccctccctatgcctcctggatttatatgtt gaagtactaattgccagtatatcaaaatgtgactgtattttgagatagggtcagttaaaatgaggtcatgagggcaggtc ctactgcaatatgactggtatctttagaaaaacagataagggtatagatacacagagatagaaaaccatgtgaagacact gggagaaaatggccacctataagccaaggagggaggactccaaagaaaccaacactgctggtaccctgatttcagacctc tagcctcctgaattgtgagaaaataaagttctattatttaagtcaccaagtctgtggtactttttatagcagccctagca gactgatataaacacctattgaagataaaatttcttagaaagtaggtgtggagaactgcctcaacttggtacaaaacatg ttcaaaaagtctagagctaccatacttaatggtgagtacaagactgaatgtttttctgctaggactggaaactaagcagg ga atcttctctcaccacttttactcaacataattgtctgagttttctgttgcttataacagagtacttgaaatgcataa tttataaagaaaggaatttatgtcttatggttatgagactgaaaagttcaaggttgaggagccacatctggtgagggcct tcctgctggtgggggctctctggagtccagaggtgacaaaaagcatcacatggcgaggggctgaatgtactcatgtgcta gctcaggtctctcttcctcttcttataaaactaccggttccctttccgtaataacacattgatactctaatccattcatg agggcagagccattgtgatccaattacctcttaaagccccacctctcaatactgccacattggggattaagtttcaatct gaattttggaggggacattcaaaccacagcaataatattggaagtttagccaaattatgaagcaggagagaaaaaatgta tgagaaaaaaataaataaaaggcacacagattggaaaggaaaattatacatcaccccaagttttttggagagaaagtagt aaaaatgggtatattttgtttagaaagtaatgcaaattaaaaccacaatgacatattattacatgcagctataagcgtat acagaataaaaaatagtgatgatgctaagtaaatataaatgaacaagggtgataatgctggcaaggatgtggagaaactg gatcattcatacattgctggtgatgatgtaaaatgatacaggcactgtataaaatagtttggcagcatcctatgaaacaa aacatgcatttgccttacaatccaacaattgtgctcttagacattcatccttgataaatgaaaactacgtgcacacaaaa atatgtacatgaatgttcacagagattttttcatgactgccaaaaactggaaacagatgtgcttcagttggtaaaatctg tgatatatcatgtcagggaatactacagagcaataaaaaggaacaaactagtgatacccacaagttaggtggatctccag ggtattatgatgagtgaaaaaagccagtcttcataaagaaactgtggtacatttataaaatagaatattatccagtgata aaaagaaataagctatcaagccatgaaaagaaatggagaaaccttcaaagtcatattgttgagtgaaagatggggacgcc aatctgaaaaggcttcacactgtatgatcccaactatgacattttgaaaaaggcaaagctatggagacaataaaaagatc agtggttgttaggggtttggagggaaggagaaatggctaggcagagcacaggctacttttaaagcagtgaaaatattaat atatgatgatgggtggcattatacatttgtcaaaacctgtaaaacatacaacacaaataatgagccctaatattctgtac acttaagatcataatagtgattcaccaactataacaaacacaccacactaatgcaagatattaacaatagggaaactggg gtggagaacaaaggggtgtataagtctctgtactttctgctagtttttctgtaaacctaaatggctcataaaaatgtcta tcaattcttttaaaagctaatttcagaaggttacatatgatatgagtccgtttacataatattcttgaaatgacaaaatt ataggcatggagagcagagaagtggttgccagaatttagagagattgggtgatgatgaggtatgtatggggagaaaggtg actttggttatgaaagaatagcagcagaatccttgtggtgatgaaactattttgtgtcttaactgtggtggtggtgatgt gaatctatgcaaatgataaaattgcataaaacttcacacatatgcaagcacacacactgtggcacataaaacttgtgaaa tctgaacaaggtgagtgcattgtattaatgtcaattttctgattgtaatactgtactgtggttatggaagacattaccac tgggagaagcttgttgaagggtacacaggatctctctgtatttactcttacagtttcatatgaattttaaattatctcaa aataaaaaaagaattaaaaacaatttaatgttttcagtaggttgttctcataatatttaaagcagggcatagtttttaat attgtctaattttgtttcctttcagtctatgcatattgatgctactttatatacggaaagtgatgttcacgtgagtatac tttttttcaaaattgctatttgtcttgttattaaagtttttaaaagtatatttttgtaacaactaaaatatggtagtttt aaaatctaacttttggtgtgtttctataatatatggtccatgagttttattagtgattattgagatgggacttggggaca gatagctacatcaatgctatttttgtaatggtgccaaatcaaaatattaaaagagtcttttccatcaatgtcaaacaaga tacattatacgtttttgtgatgcagttgcatcatggtgcaattagatgcaaaaatcagattaactgtttcaatttaagag tagccaatatatcagttatttccaatgctgtaatgtatcaccatctgcaatcatattttccataaattgcttaaaatcat tcatgttctgcattttacatgattctctacatttgtcagaaaaagattctaattattctctatgtgagaaaggaaacata acccatgaaacttattagaactgaaaaatggtcttgaacttgtttcattaataccctgacatttcctaaggaatgtagga tttgtcatgttggtggtggttcttcccttcagtattgttactaaaaccaagaaatgaatccccaacttcacgtcagggaa aacaaactctatgtcctctctccattattcctcaattagaacttctcttacatagatgactttctaagcattggaaagaa accatagtcagaaactagaaaaaagagatattcactaaccaattgggtcatgctgctgcacaaagaaattgtctccctcc tctggcttcagcatggattctgtttttctttgcattttttgtaaaatggaaagtagtcaattagccaccaaattcagcat cctgaaattgcttttttgcaagaagataactttgcaacccatgggttagagaaacaaccttagattttagattttagatt ttagaagtttagattttaaaactgactccaccactttttacttgtgttaccttggagattgctaaacatttctgaagctc atttttattattgctgatatggtgacagtatttgtctttcaatcctaagcagtgactgttgggtttaaggaatattacca gtgctgggcacatgggtgtattccttcattttttttatccattcagtaagcatttgtgaagtgtctgcaggctcccaggt actgtgcaaggtatcgaggacacaaagtcaaataatggtcaaatccctagatattccttgtttcctttctttaagttatt gttaaagtaaatgttgtggaaaacatatttttgtggcacctaagagagccttttctgatttgatctgcctgtaagtggac actagtcctgctttgatttttctaataaatttcttggaattacttctctccctctggaactttggaacttgaaagaacag tataattagcagctaccactatttaaaatgttaacaacacaatttgattctaaaaattcttacaaataaactgtctatat tgatgttttcagactctaaggccagtattattaccctttccacaggggaaatgtgctcggtgagaaaaactggccactat ttctgcattttctagtttcatgttcttctgtacaatattgccatccttcttgattgtgttttgttggtttgttttggttt ttattttaaagccaaaagaaaaaaaattaagctgcctcctatgtaaaatttcttaaggatattgtgtatctttataaaat atttggattgactttttgaaaatcaaaattacatcagtatgaaaattaataatcagaaaaaagtaattgttctttataac ttttatttttagcccagttgcaaagtaacagcaatgaagtgctttctcttggagttacaagttatttcacttgagtccgg agatgcaagtattcatgatacagtagaaaatctgatcatcctagcaaacaacagtttgtcttctaatggggtgagttttc caacagttgcttagagttgcatcttatgttttgggcctgatttggagaagtcattcatggacaagcagatcctcctaagg ggcaatcaggagaaggagtcctgttccagtggagtggtgtgcaaaagtggcaccatctccagcatgcacacaatgctaaa ctgttcaatgattgattcagtagacaaacatttacagaataatgccaggtagtgtgcttcagtgctagaattatagttgc aaaccagacagacaggtcactgacctcaaggtgtttattgtcaggtgcagtggatagacattaatctaattacatactca aatgtctaacatcaataatagtaactcacatttattgagttattactgtatgccagacactattctttgagctttaaatt gataattcatttaatcctcatgataaatctgtgagatagttatctttatttctgtttgaatgttgaagaaattgtagcac tgagagcctggatcactcgcttcagttcatacagctagtaaaatggggagccacaactcttacccgagcagtctgtctgc agagtctgttatctcatgagaagataaatgctttaaaaagataacaatgaaaatattaatgattcgagtataatctggga catcccaggcaacttgagcagtagagggttccaggagagcaaattctaggtactcgtatgataggctggggaatcagctg tgcaatggccctgaagtgcaaagaattagggctttcatggcaaaacaccagtggccaaagcaaggtagagagaaagcagt tttgcaacaaagaggcataatcaaattagttcatttcataaatactttttagccctcaggagacagtatgaaaaaatacc cataatccctgctgttaaagagggaggaaacagaaataaaccaagcactcagcaaatgagtaataagttagttatttatg aagtccagtggtgaaaaaggacacagggtaggggcactggggctccagttagggtaggctgagctaataagctgccattt gacaaagatgtgagagaatgagccttaagggtatctagggacatatgtttaggcagagacaactgaaagtgcaaaggccc taagcttgtgtgggtggacaccttgacttttctctaaaaatacaagactgctttaggtctttgcttcagtgtcaccttct cagtgatttacctatttacagttgcaatcccttccctatctgagcactccctgtccccttctctgcgtgtcccatatctg gaatatgatatattttatgtaatgggtattgtctgtttttccctactagaatgtcagcttaaaatggacaagtgtttttg ttttttattagtactatatccaaattcccagaacagtgtctcatata attaaatactttacatatgtatgaaatgaatt tattaaggtttataatactcttatgatgttatctccatcttattggtggaaagagtgagccacgcaacaggtaactcatg gcaaaataaatgatgagctctttaatgtgaatgttgatagtcatcctcatcatgacagagtgtgacatacgtgctggaat gcgtgggcaggactgcacagtcagaagacctggatgggaagaatttcagttgattatgtcagttgagatgagtcaatatc tctgtcttcctatctgacatgattattttcaggatcaaataggacagcattatatgaaatatgacagtgcttggcataga ggatgtgcttgataaatgtcgctgattctgaattccaaatagttaatggatataaaatctaatttttatttttgctggca cagccttcatggttcagatgatctctaaaaagtttattcttaattgctacatttggaacattctagttatccatgagact gtgtttgaagtacaacaatttgtggtattcacctaaatggctcagttcaaccaatgggtgattacagtgtgtcaggccct gtgctaaatgctagggaaacaaacatactggctctgaccttctggcagagagcttagagaatagtattacagtataaaaa gagtaaaacttcataatatgaatagaatacatgacatattgtgagagaggtctaaataaggggttctgagatgtaaagat gggacattgagtccagccctaggagcccaggggttcagagaagcctccctaaaagagtacctgaataatcttaagtgcga gtagcagcagctaaaataggaatgaatgtaacagagagaaaagcaaaggcagagaggcatctaatagtatgctgtgcatg gcaaggaaagccagatgctcactcagtgtttctagggcataacattgaggcaagggggatatgtgaaataaataggtaag gaacagctcatgaagagcctgtgtgctatgcagggaggcatggtctttatgctagaagcagatgataggaaaccattga , gggctcaaagcaggaactccgtggtctgatagacacagcttatttttctcaatgtccttaacccattattggaaaaataa acatatatcaaatctccctgttctctttcctcgtagttcttcctaatatgctattta ttgctaaagctttcatatctca agacctcaccatatggttcaaacgatatgatattcccattcccatgaatgtatatttaatttaattataaattgccaatt taatctctctctatattttgcagaatgtaacagaatctggatgcaaagaatgtgaggaactggaggaaaaaaatattaaa gaatttttgcagagttttgtacatattgtccaaatgttcatcaacacttcttgattgcaattgattctttttaaagtgtt tctgttattaacaaacatcactctgctgcttagacataacaaaacactcggcatttcaaatgtgctgtcaaaacaagttt ttctgtcaagaagatgatcagaccttggatcagatgaactcttagaaatgaaggcagaaaaatgtcattgagtaatatag tgactatgaacttctctcagacttactttactcatttttttaatttattattgaaattgtacatatttgtggaataatgt aaaatgttgaataaaaatatgtacaagtgttgttttttaagttgcactgatattttacctcttattgcaaaatagcattt gtttaagggtgatagtcaaattatgtattggtggggctgggtaccaatgctgcaggtcaacagctatgctggtaggctcc tgccagtgtggaaccactgactactggctctcattgacttccttactaagcatagcaaacagaggaagaatttgttatca gtaagaaaaagaagaactatatgtgaatcctcttctttatactgtaatttagttattgatgtataaagcaactgttatga aataaagaaattgcaataactggcatataatgtccatcagtaaatcttggtggtggtggcaataataaacttctactgat aggtagaatggtgtgcaagcttgtccaatcacggattgcaggccacatgcggcccaggacaactttgaatgtggcccaac acaaattcataaactttcatacatctcgtttttagctcatcagcta cattagcggtagtgtatttaaagtgtggcccaa gacaattcttcttattccaatgtggcccagggaaatcaaaagattggatgcccctggtatagaaaactaatagtgacagt gttcatatttcatgctttcccaaatacaggtattttattttcacattctttttgccatgtttatataataataaagaaaa accctgttgatttgttggagccattgttatctgacagaaaataattgtttatattttttgcactacactgtctaaaatta gcaagctctcttctaatggaactgtaagaaagatgaaatatttttgttttattataaatttatttcaccttaattctggt aatactcactgagtgactgtggggtgggaaatgatctcttaagaatttgatttctttctattccatagtacaaactcgtt ctctgttgaaacattcttctatcaccccagtgccctatccatgtacatgtgttcttattgctctagtcaaacggtgctta taaatatctttcagaaagcttaggagaaatctgtatcctatttgacttccaataatcacggattgggatcggacctactt gattcacttctgggaaatcaaggatctacgtaccatggattttcaggtgcagattttcagcttcctgctaatcagtgcct cagtcataatgtctagagccaactgggtgaatgtaataagtgatttgaaaaaaattgaagatcttattcaatctatgcat attgatgctactttatatacggaaagtgatgttcaccccagttgcaaagtaacagcaatgaagtgctttctcttggagtt acaagttatttcacttgagtccggagatgcaagtattcatgatacagtagaaaatctgatcatcctagcaaacaacagtt tgtcttctaatgggaatgtaacagaatctggatgcaaagaatgtgaggaactggaggaaaaaaatattaaagaatttttg cagagttttgtacatattgtccaaatgttcatcaacacttcttgattgcaattgattcctcgag (SEQ ID NO: 12281) cccagagcagcgctcgccacctccccccggcctgggcagcgctcgcccggggagtccagcggtgtcctgtggagctgccg ccatggccccgcggcgggcgcgcggctgccggaccctcggtctcccggcgctgctactgctgctgctgctccggccgccg gcgacgcggggcatcacgtgccctccccccatgtccgtggaacacgcagacatctgggtcaagagctacagcttgtactc cagggagcggtacatttgtaactctggtttcaagcgtaaagccggcacgtccagcctgacggagtgcgtgttgaacaagg ccacgaatgtcgcccactggacaacccccagtctcaaatgcattagagaccctgccctggttcaccaaaggccagcgcca ccctccacagtaacgacggcaggggtgaccccacagccagagagcctctccccttctggaaaagagcccgcagcttcatc tcccagctcaaacaacacagcggccacaacagcagctattgtcccgggctcccagctgatgccttcaaaatcaccttcca caggaaccacagagataagcagtcatgagtcctcccacggcaccccctctcagacaacagccaagaactgggaactcaca gcatccgcctcccaccagccgccaggtgtgtatccacagggccacagcgacaccactgtggc atctccacgtccactgt cctgctgtgtgggctgagcgctgtgtctctcctggcatgctacctcaagtcaaggcaaactcccccgctggccagcgttg aaatggaagccatggaggctctgccggtgacttgggggaccagcagcagagatgaagacttggaaaactgctctcaccac ctatgaaactcggggaaaccagcccagctaagtccggagtgaaggagcctctctgctttagctaaagacgactgagaaga ggtgcaaggaagcgggctccaggagcaagctcaccaggcctctcagaagtcccagcaggatctcacggactgccgggtcg gcgcctcctgcgcgagggagcaggttctccgcattcccatgggcaccacctgcctgcctgtcgtgccttggacccagggc ccagcttcccaggagagaccaaaggcttctgagcaggatttttatttcattacagtgtgagctgcctggaatacatgtgg taatgaaataaaaaccctgccccgaatcttccgtccctcatcctaacttgcagttcacagagaaaagtgacatacccaaa gc ctctgtcaattacaaggcttctcctggcgtgggagacgtctacagggaagacaccagcgtttgggcttctaaccacc ctgtctccagctgctctgcacacatggacagggacctgggaaaggtgggagagatgctgagcccagcgaatcctctccat tgaaggattcaggaagaagaaaactcaactcagtgccattttacgaatatatgcgtttatatttatacttccttgtctat tatatctatacattatatattatttgtattttgacattgtaccttgtataaacaaaataaaacatctattttcaatattt ttaaaatgca (SEQ ID NO: 12282) atgcctgacctcaactcctccactgactctgcagcctcagcctctgcagccagtgatgtttctgtagaatctacagcaga ggccacagtctgcacggtgacactggagaagatgtcggcagggctgggcttcagcctggaaggagggaagggctccctac acggagacaagcccctcaccattaacaggattttcaaaggagcagcctcagaacaaagtgagacagtccagcctggagat gaaatcttgcagctgggtggcactgccatgcagggcctcacacggtttgaagcctggaacatcatcaaggcactgcctga tggacctgtcacgattgtcatcaggagaaaaagcctccagtccaaggaaaccacagctgctggagactcctag (SEQ ID NO:12283) tgcttaaaaaaacacaacaggattttcgaagaatcctttcttagaaaacaaacaaaaaaaccaaacaaaaacgtactttc tccccactagtttacaccacaggaagcgagagagctgctgccactgctgctaccacaggaagacacagcagggagaagcc ctagtgcctctgccggctgcccaggacctggtatcggcccacagaccaagtcctccacagagggcgagccagggtggaga agagccagcccagtgacccaaacatccccgataaaacacccactgcttaagaggcaggctcggatggactatagctttga taccacagccgaagacccttgggttaggatttctgactgcatcaaaaacttatttagccccatcatgagtgagaaccatg gccacatgcctctacagcccaatgccagcctgaatgaagaagaagggacacagggccacccagatgggaccccaccaaag ctggacaccgccaatggcactcccaaagtttacaagtcagcagacagcagcactgtgaagaaaggtcctcctgtggctcc caagccagcctggtttcgccaaagcttgaaaggtttgaggaatcgtgcttcagagccaagagggctccctgatcctgcct tgtccacccagccagcacctgcttccagggagcacctaggatcacacatccgggcctcctcctcctcctcctccatcagg cagagaatcagctcctttgaaacctttggctcctctcaactgcctgacaaaggagcccagagactgagcctccagccctc ctctggggaggcagcaaaacctcttgggaagcatgaggaaggacggttttctggactcttggggcgaggggctgcaccca ctcttgtgccccagcagcctgagcaagtactgtcctcggggtcccctgcagcctccgaggccagagacccaggtgtgtct gagtcccctcccccagggcggcagcccaatcagaaaactttcccccctggcccggacccgctcctaaggctgctgtcaac acaggctgaggaatctcaaggcccagtgctcaagatgcctagccagcgagcacggagcttccccctgaccaggtcccagt cctgtgagacgaagctacttgacgaaaagaccagcaaactctattctatcagcagccaagtgtcatcggctgtcatgaaa tccttgctgtgccttccatcttctatctcctgtgcccagactccctgcatccccaaggcaggggcatctccaacatcatc atccaacgaagactcagctgcaaatggttctgctgaaacatctgccttggacacggggttctcgctcaacctttcagagc tgagagaatatacagagggtctcacggaagccaaggaagacgatgatggggaccacagttcccttcagtctggtcagtcc gttatctccctgctgagctcagaagaattaaaaaaactcatcgaggaggtgaaggttctggatgaagcaacattaaagca attagacggcatccatgtcaccatcttacacaaggaggaaggtgctggtcttgggttcagcttggcaggaggagcagatc tagaaaacaaggtgattacggttcacagagtgtttccaaatgggctggcctcccaggaagggactattcagaagggcaat gaggttctttccatcaacggcaagtctctcaaggggaccacgcaccatgatgccttggccatcctccgccaagctcgaga gcccaggcaagctgtgattgtcacaaggaagctgactccagaggccatgcccgacctcaactcctccactgactctgcag cctcagcctctgcagccagtgatgtttctgtagaatctacagcagaggccacagtctgcacggtgacactggagaagatg tcggcagggctgggcttcagcctggaaggagggaagggctccctacacggagacaagcctctcaccattaacaggatttt caaaggagcagcctcagaacaaagtgagacagtccagcctggagatgaaatcttgcagctgggtggcactgccatgcagg gcctcacacggtttgaagcctggaacatcatcaaggcactgcctgatggacctgtcacgattgtcatcaggagaaaaagc ctccagtccaaggaaaccacagctgctggagactcctaggcaggacatgctgaagccaaagccaataacacacagctaac acacagctcccataaccgctgattctcagggtctctgctgccgccccacccagatgggggaaagcacaggtgggcttccc agtggctgctgcccaggcccagaccttctaggacgccacccagcaaaaggttgttcctaaaataagggcagagtcacact ggggcagctgatacaaattgcagactgtgtaaaaagagagcttaatgataatattgtggtgccacaaataaaatggattt attagaattccatatgacattcatgcctggcttcgcaaaatgtttcaagtactgtaactgtgtcatgattcacccccaaa cagtgacatttatttttctcatgaatctgcaatgtgggcagagattggaatgggcagctcatctctgtcccacttggcat cagctggcgtcatgcaaagtcatgcaaaggctgggaccacctgagatcattcactcatacatctggccgttgatgttggc tgggaactcacctggggctgctggcctgaatgcttataggtggcctctccttgtggcctgggctcctcacaacatggtgt ctggattcccaggatgagcatcccaggatcgcaagagccacgtagaagctgcatcttgtttatacctttgccttggaagt tgcatggcatcacctccaccatactccatcagttagagctgacacaaacctgcctgggtttaaggggagaggaaatattg ctggggtcatttatgaaaaatacagtttgtcacatgaaacatttgcaaaattgtttttggttggattggagaagtaatcc tagggaagggtggtggagccagtaaatagaggagtacaggtgaagcaccaagctcaaagcgtggacaggtgtgccgacag aaggaaccagcgtgtatatgagggtatcaaataaaattgctactacttacctacc (SEQ ID NO:12284) atgcctgacctcaactcctccactgactctgcagcctcagcctctgcagccagtgatgtttctgtagaatctacagcaga ggccacagtctgcacggtgacactggagaagatgtcggcagggctgggcttcagcctggaaggagggaagggctccctac acggagacaagcccctcaccattaacaggattttcaaaggagcagcctcagaacaaagtgagacagtccagcctggagat gaaatcttgcagctgggtggcactgccatgcagggcctcacacggtttgaagcctggaacatcatcaaggcactgcctga tggacctgtcacgattgtcatcaggagaaaaagcctccagtccaaggaaaccacagctgctggagactcctagtgcttaa aaaaacacaacaggattttcgaagaatcctttcttagaaaacaaacaaaaaaaccaaacaaaaacgtactttctccccac tagtttacaccacaggaagcgagagagctgctgccactgctgctaccacaggaagacacagcagggagaagccctagtgc ctctgccggctgcccaggacctggtatcggcccacagaccaagtcctccacagagggcgagccagggtggagaagagcca gcccagtgacccaaacatccccgataaaacacccactgcttaagaggcaggctcggatggactatagctttgataccaca gccgaagacccttgggttaggatttctgactgcatcaaaaacttatttagccccatcatgagtgagaaccatggccacat gcctctacagcccaatgccagcctgaatgaagaagaagggacacagggccacccagatgggaccccaccaaagctggaca ccgccaatggcactcccaaagtttacaagtcagcagacagcagcactgtgaagaaaggtcctcctgtggctcccaagcca gcctggtttcgccaaagcttgaaaggtttgaggaatcgtgcttcagagccaagagggctccctgatcctgccttgtccac ccagccagcacctgcttccagggagcacctaggatcacacatccgggcctcctcctcctcctcctccatcaggcagagaa tcagctcctttgaaacctttggctcctctcaactgcctgacaaaggagcccagagactgagcctccagccctcctctggg gaggcagcaaaacctcttgggaagcatgaggaaggacggttttctggactcttggggcgaggggctgcacccactcttgt gccccagcagcctgagcaagtactgtcctcggggtcccctgcagcctccgaggccagagacccaggtgtgtctgagtccc ctcccccagggcggcagcccaatcagaaaactttcccccctggcccggacccgctcctaaggctgctgtcaacacaggct gaggaatctcaaggcccagtgctcaagatgcctagccagcgagcacggagcttccccctgaccaggtcccagtcctgtga gacgaagctacttgacgaaaagaccagcaaactctattctatcagcagccaagtgtcatcggctgtcatgaaatccttgc tgtgccttccatcttctatctcctgtgcccagactccctgcatccccaaggcaggggcatctccaacatcatcatccaac gaagactcagctgcaaatggttctgctgaaacatctgccttggacacggggttctcgctcaacctttcagagctgagaga atatacagagggtctcacggaagccaaggaagacgatgatggggaccacagttcccttcagtctggtcagtccgttatct ccctgctgagctcagaagaattaaaaaaactcatcgaggaggtgaaggttctggatgaagcaacattaaagcaattagac ggcatccatgtcaccatcttacacaaggaggaaggtgctggtcttgggttcagcttggcaggaggagcagatctagaaaa caaggtgattacggttcacagagtgtttccaaatgggctggcctcccaggaagggactattcagaagggcaatgaggttc tttccatcaacggcaagtctctcaaggggaccacgcaccatgatgccttggccatcctccgccaagctcgagagcccagg caagctgtgattgtcacaaggaagctgactccagaggccatgcccgacctcaactcctccactgactctgcagcctcagc ctctgcagccagtgatgtttctgtagaatctacagcagaggccacagtctgcacggtgacactggagaagatgtcggcag ggctgggcttcagcctggaaggagggaagggctccctacacggagacaagcctctcaccattaacaggattttcaaagga gcagcctcagaacaaagtgagacagtccagcctggagatgaaatcttgcagctgggtggcactgccatgcagggcctcac acggtttgaagcctggaacatcatcaaggcactgcctgatggacctgtcacgattgtcatcaggagaaaaagcctccagt ccaaggaaaccacagctgctggagactcctaggcaggacatgctgaagccaaagccaataacacacagctaacacacagc tcccataaccgctgattctcagggtctctgctgccgccccacccagatgggggaaagcacaggtgggcttcccagtggct gctgcccaggcccagaccttctaggacgccacccagcaaaaggttgttcctaaaataagggcagagtcacactggggcag ctgatacaaattgcagactgtgtaaaaagagagcttaatgataatattgtggtgccacaaataaaatggatttattagaa ttccatatgacattcatgcctggcttcgcaaaatgtttcaagtactgtaactgtgtcatgattcacccccaaacagtgac atttatttttctcatgaatctgcaatgtgggcagagattggaatgggcagctcatctctgtcccacttggcatcagctgg cgtcatgcaaagtcatgcaaaggctgggaccacctgagatcattcactcatacatctggccgttgatgttggctgggaac tcacctggggctgctggcctgaatgcttataggtggcctctccttgtggcctgggctcctcacaacatggtgtctggatt cccaggatgagcatcccaggatcgcaagagccacgtagaagctgcatcttgtttatacctttgccttggaagttgcatgg catcacctccaccatactccatcagttagagctgacacaaacctgcctgggtttaaggggagaggaaatattgctggggt catttatgaaaaatacagtttgtcacatgaaacatttgcaaaattgtttttggttggattggagaagtaatcctagggaa gggtggtggagccagtaaatagaggagtacaggtgaagcaccaagctcaaagcgtggacaggtgtgccgacagaaggaac cagcgtgtatatgagggtatcaaataaaattgctactacttacctacc (SEQ ID NO:12285) gaattcatgccacaactgagtgattttttttttctcaaacccaattccacaaagtaaaagcctgatgaaatacagtgaag gctgatgcttattaactgtgtttcccaaatccagagctctaaaaaggttctgcatacagtcattcattcaatgcttaacg actgagcattaattccatgctaagtactgaactcagcactaggaataagaaggcgacctagaggcatatcctctctctaa agatgcatagagcctcattggaatgatcagccgtgtctccagagagctacaaggcagttttcaattggtaaatgccctga gagtgatgggcttgtggcatgtgtaagggttagacagacctgggacctagacatgacaccactcctgacgaattatgtga gtgtgggtgtttcacaaccacaatgagatgcaatgcctgcacttgtaacatggaaatagtgatggcatgccccgcagatt gctgtgagaagtcagcggcagagacatgcaacattctcagcacagtgcttgccatgtagtaagggcctagtcagtgctag tgattcctttcaatattcctaagatgcagataagggaacagcccagaggagggggagcacttccagagggaggaatgcgg tgagacttccttcagcagggtagcactggagctgggtgttaaggagtgagtgagctttgggcttatggatttaacagagg aaaccaagaaaagaggaggcggtgttgcaggaacagtgagcagttgatgatttttattttgttctctggtctgcttggga acatttttgtggcaaagacagcatgaaggatagcgaagaattaatactgaagagataggccagggcaggttatgaaggat tttgaataccgggctaagaaatgtgggcttaatttcaaagacattatggacactcctaaaatgttacgttgtagataagg gaaaagtattcttccagaagattaaattggggctgggcacggtggctcacgcctgtgatcccagcactttgggaggcgaa gtgggcagatcacctgaggtcaggagtttgagatcagcctggccaacgtggtgaagccccatctctactgaaaaaaaaaa ttagccgggcatggtggtgggtgcctgtaatctcagctacttgggaggctgaagcaggagaatcacatgaacctgggagg cagaggttgcagtgagccaagattgcaccactgcattccagtgggcgacagagcaagactcagtcaaaaaaaaaaaaaga ttaaactggaagcaatgggtaagaatggtggagtggagagacacatttgagtgagggaagccagctgaaaagctgtacag acgtctagacaaaatgtgacacaagcatgccttcacctccctgcaaagaccacagaccactgagctccaaagggggtttg gaatccttgtcctgggccgccattggtaac catcagtgctggcttgagagataaactctattatccatccctgaactaa aatcatgacagaagtggccagggagctttgctgctatccccccaggaaacacgtcctccactcaaatggaaagaggaccc tctgacaacatctgtgggacccaacagcactggtcaccacaagccacaaaatgttaacaaagtcagttttcaattgttag ggacggaggactcagttcatgattcatacaaaccaactgttctctcccagtgttttctgggtggcacaacccacaagtca acagtggcttgggaactagacatttgagtagagttgggttatttgattcatagtggattttggttttccacgggacccct gtgcccttgtctagtagaatctggtggaaattacaaactgcagaaattcaactcagtgccgcaataacaggatgcacctg tagatttcgtagaattagcagcagcattctttcaataccagtttgagagaaataaccctgtttgcatagtgccaactggg gcagaatctgaagtgtcttgcctgcctctcggccatgggaggcaccgatctcagcaacatctatccaaccgccatccact taacaagcaaagatggaaggccctcgtgctccaggc at ctgcaatggttcatttgcttttgatgggattatcactttg acagatgtgcttgcaattaactgggggctttctgcttccaatccaaattcccacaggtggatcactggctcttggggagc aaaaacccttctttgtttgtttttgcttctcccagagcctgggcagagctccccattcctggatcctacgttgatatgca ctgaattgaatta actaaagggtgcacccaagagtgcatgagctaagtaaaatgtaatttgtgggacctcatgtggaca tttcaggtccatgtgtacaagataaaggagagaaaatcctgggggacaccacaggcctgggaaaatgacctcctactaag cctaacaagaacatccagtacataaacagcaggctctctgcaaccgcttcggtccttccactgccacgctcccagaaagc aaagggttatctcctgttcggattttggctctgagaccacagctcagcacatcactcctctagagaaaagaaagtctaag atgagagagtgaggctgctttcatgtggtgccagcgtatagtgcagggcaggcctgattgctgaacggatccctgcagac gtgagcggtcacttccccttttgagggcccatttcttttcctctttgaggagactgtgagcgtcctcagtgcagggctat gttttagcttcttggctctcctcacaggttctagcataattctttgattaattgcagtcaacgtttattgatggattatg tgacagaggtgaaattctttgatctgggtttcagcttttcctttcccccactccctcctttttctttttttttttttttt tttttagaggcgaggtcttgctctgtggccctggctggagtgcagtggtgcaatcatagctcattgcagccttgacctcc tggggtcaagcgaacctcaacgtcttggcctcctgagtagctgggactat ggcatgcgccaccacgctcagcttcacct tttcctttccttgtgctcccctggcagatatgctggtaaacaatgaaccagtcaagaggacagcaacaggaggaaaatgg gagaaaccccattattcgtggactaaacaggcttcccactagtcctggctcacagaggaagtcatgctccatgtttcaaa tgtcctcaaagctcgttcaactccaaaatgcatgaagacaaaatgggaattttactcaagatttttgtgggctgttgggg agaagagttaacattgcaaagcatattgcaaactcttatcttcaaatgattttaaaattttcttccaagctctttattat ttctccagagctgccctgctcttcccactctgggtcctttctctgccactctcctcagcatgacttctccctaatcggcc agcatttcttttattctatagagcaagttttcttgccctgggcacctctcatttgcatgttataccaccacaccaagtga gcctcagagcaccagtgttttaatccctgaaaacagtccttacgggattcagcacagaggtcctcttggcagcctgtagt ctccagagtgacacgtcctcaacagtcaaagtgagcaagctatggtgcccatcaccaagtggggctcaccatttccctct gcgttcacttctctcctaccttcttccttatcccatccttcctccttcctttttttttctgcattcaattattcatggtt attcatttcatacgggcatctgtgccacttggttctacaggcatttttttttttgagacagacttttgcccttgtccccc aggctggcgtgcagcggtgtgatcttggctcactgcaatctccacctcctaggttcaagcaagtctcctgccttagcctc ccaagtagctggaattacaggcatgtgccaccaagcccggcaaatttttgtatttttagtagagacagggtttcaccatg ttggccaggctggtctcaaactcctgacctcaggtgatctgcctgcctcggcctcccaaagtgctgggataacaggcgtg agccatcgtgctcggccggttctatgggcattgtggaagtgaccgttaacaagccccaagggtaagtaaaggaaaatgaa aggtgattgattcctcaccacctctccccttttttcctctactctttgcccctgctccccaatctagactctaataaaca gaaatgatttttgttgcaagctgaaaactcgttcttgtggttggggctaggggggtggcaagtcaagctttagagttgtc tggataataaatgctgtcttcaaggactgtccaacattgtaggaacaagagaacaacccaagtgaacaactaactcctgt tcacaaatgctactgcctctctgccatcccctaacctcagcctcacacacttgaatttcgccaatccatttgatgagctc aaatcagtgaattttctcctcgccaaagctcacaaattctgttccccgcttcttgccccacatccaggcattaccaactg cattttccctttgcctgatattctggcatcaagcctccttgccattccaatttatttcaccttcctccagtccttatgat ttccttcctgaagagtatttcagcatctctatgcctcaatcttccctgcacaccacaccagctcggcctca catcacat tacttggctatgtcccgcctgggttagacagcttcagtggctgaagtccatagatcttattctgtttttcgaggtccacc tgactctgaatccagctgacatttctgcccttagcttctacccctctctacttctggttaactatggaccacactctgct tcctcaggaaccacctaccaaggccgtatccatccttcaaggacaatacgtgggcctttcctgatcacatcagctcaaca acttttccctcctacatttcaattgctcttcttaccataatcattagtattcaccccactgtacgtctagaaagaaagtg gtcttaaacctaagggaaggcagtctaggtcagaaatttgttgtccgctgttctgagcagtttcttctaggaagtaccaa acatttctgataatagaattgagcaatttcctgatgaagtgagactcagcttgcactgttgaccggctgtcctggatgaa cctagttacttttaaccaaatgttcctttcttgaacttgttcctttcttgaacttaatctatcaatgttatctagataac tttcctcaaaaaaaaaaaaaaaaaaaaaaaccctctactaggaaagaaatctttgaaccggacttattggaaattacctc cttgcagcaggtttgaaacaaaactttgaatttgcctcacaaagaatttgtctgaaactgctttagtatatgctagt at atttgtatgcacatgtggcttcatacatagtggttggacacccatatgtgttatgcactttgttaggtgacgtaagttca cagataaactggaacatagggctatcctctagaggcccacagtttgacaccttaacctgagatccttggacctttgaagt tcagagtgcccacaaccgctgggtgtggtggctcacacttgtaatcccagtactctgcagggctgaggtgggaggatcgc ttgagtccaggagtctgagaccagcctgggcaacatgacaaaaccccatctctacaaaaattacaaaaaaaattagccag gcctggtggtgcatgcctgtggtcccagttacttgagaggctgaagtgggaggatcacttgagtcaaggaggtagaggct gcagtgagttgagatggcaacactgcactccagaaaccccatctcaaacaaaacagagcaaaacaaaacaaactgcccat aatgctcctgaaacttcctacggatttatccagagtatgtgctgatgtgcattttttccaaggagggaaaccaaaggttc tatcaaattaagaaaagagtttttaccattgtggaagacagtatggcgattcctcaagcatctaaaatcagaaataccat ttgacccagcaatcctattactgggtatatacccaaaggaatagaaatcattctactataaagtcacatgcaaccgtatg tttattgcagcactatttacaatagcaaaatggaaccaactgaaatgcccatcaatgagactagataaagaaaatgtgat acatatacaccatggaatactatgcagccatgaaaaggaatgagatcacgtccttggcagggacatggatgaagctggaa gccatt tcctcagcaaactaacacaggaacagaaaaccaaatgccgcatgttctcactcataagtgggagttgaacaat gacagcacatagacatagggaggggaacatcacacgccagggcctgctgcagggtggggggtggggtgtgaggggaggga acttagaagacaggtgagtaggtgcagcagaccaccatggcacacttatacctatgtaaccaacctgcacgttctacaca tgtatcctggaacttaaattaaaaacaaaaaagagtttttaatccaagaaagattaacagcaactagaagaaagaaagag atataaacagtgaattgcaatgcagcacggcaggtgttatgatggagtagaaaggactggaaaaggcctcctggaggaag ggacactcaagtgtctttccatttcacctgtaaactcattaagggcaaaagctttgctacagcttcagtatgagatcctg ggcaatccgtgacaaaatgggtctgcttttgcacccccaacttcttctcacatccctgcatcgtgccatgcagcatcaac tggaaacctcagcgtcagcaaacgacgacagagcgttcatccgtaaggtgaaccagaaaagccagttcaatgacttgttt aaccatggtccatctcagaaccaagagttgggcctcttatttaccagaaaaattgtgggggctttgtgatatggctttaa aaaaatcttgtaattgccaggcgtggtggctcacacctgtaatcccagcactttgggaggccgaggtgggtgaatcgcct aaggtcaggagttcgagaccagcctgaccaacatggtgaaactccgtctctactaaaaatacaaaaactagctggatgtg gtgacgcgtgcctgtaatcctagctactcaggaggctgacgcaggagaatcacttgaacctgggaggcagaggttgcagt gagccaagattgtgccattgcgctccaaaaaaaaaaaaaaaatacattaacataaatttaaatattttataatgacaatc cacattaactacttaaagcataagctattttccaggagaggcagcaagtgcattctactcccatgcccaagaagaaagga gcgtgactttggtgggagtactaggagtttctactggagcacttgcccgcagagtgagaaacgttcctagagaggaagtt atacctgctgtggaatttaagagaatcttgtcatattttgacaagttttttgagatggaagtctcactctgtcgcccagg ctggagtgcagtggcgcaatctcagctcactgcagcctgcacctcctcggttccagctattctcttgtctcagcctcctg agtaactgggattacaggcgcccgccactacgcctggctaatttttgtatttttagtagaaatggggttttaccatgttg gccagactggtctcaaactcccgacctcaggtgatctgcctgcctcagcctcccaaagtgctggaattacaggcgtgtgc cactgcgcctggctaatttttttttttttttttttttagtagagacggtggtttcaccatgtcatccaggctggtctcaa actcctgacctcaggtgatccacccaccttggtctaccaaagtgctcggattacaggcatgagccaccaggcccagtcaa cgtgatgtgttttggaaccctgaattccttggcttgccggagggttttctttttgttaatatctttgcttgctttctagt atttaaaaaattgtgttttgctctaactatgcaatggctttaagtcttagacaaatttccagggagcaaaacacactcaa ccaatttcataataatcagaagagagctctgatcaataaataagcaagactgaattttacaaaataatccaaagtttaaa accaaagcccactttttgcatgatcctttaagagaaagaaatctggaagcaaaacaccttataaaatgacaatgcacttt caggagcccagggcactgtggtgaaatgatgatggctagtacaggttataagccttggggaattatttatgaattctcag gatccttcagttcgccgcatccttctccattatttgaatattggaggctgcctgaccagaatcttgtcaggactttgctc cttcatcccaggtggtcccggctgactcctgaggacgttacagccctgaggggaggactcagcttatgaagtgctgggtg agaccactgccaagaagtgcttgctcaccctaccttcaacggcaggggaatctccctctccttttatgggcgtagctgaa gaaaggattcataaatgaagttcaatccttctcatcaaccccagcccacacctccagcaattgaacttgaaaaaaaaaac ctggtttgaaaaattaccgcaaactatattgtcatcaaaaaaaaaaaaaaaaaaacacttcctatatttgagatgagaga agagagtgctaggcagtttcctggctgaacacgccagcccaatacttaaagagagcaactcctgactccgatagagactg gatggacccacaagggtgacagcccaggcggaccgatcttcccatcccacatcctccggcgcgatgccaaaaagaggctg acggcaactgggccttctgcagagaaagacctccgcttcactgccccggctggtcccaagggtcaggaagatggattcat acctgctgatgtggggactgctcacgttcatcatggtgcctggctgccaggcaggtaagggcctgtgggtgcccccggaa ttc (SEQ ID NO:12286) gaattccccccccccccccccgagagactggatggacccacaagggtgacagcccaggcggaccgatcttcccatcccac atcctccggcgcgatgccaaaaagaggctgacggcaactgggccttctgcagagaaagacctccgcttcactgccccggc tggtcccaagggtcaggaagatggattcatacctgctgatgtggggactgctcacgttcatcatggtgcctggctgccag gcagagctctgtgacgatgacccgccagagatcccacacgccacattcaaagccatggcctacaaggaaggaaccatgtt gaactgtgaatgcaagagaggtttccgcagaataaaaagcgggtcactctatatgctctgtacaggaaactctagccact cgtcctgggacaaccaatgtcaatgcacaagctctgccactcggaacacaacgaaacaagtgacacctcaacctgaagaa cagaaagaaaggaaaaccacagaaatgcaaagtccaatgcagccagtggaccaagcgagccttccaggtcactgcaggga acctccaccatgggaaaatgaagccacagagagaatttatcatttcgtggtggggcagatggtttatta cagtgcgtcc agggatacagggctctacacagaggtcctgctgagagcgtctgcaaaatgacccacgggaagacaaggtggacccagccc cagctcatatgcacaggtgaaatggagaccagtcagtttccaggtgaagagaagcctcaggcaagccccgaaggccgtcc tgagagtgagacttcctgcctcgtcacaacaacagattttcaaatacagacagaaatggctgcaaccatggagacgtcca tatttacaacagagtaccaggtagcagtggccggctgtgttttcctgctgatcagcgtcctcctcctgagtgggctcacc tggcagcggagacagaggaagagtagaagaacaatctagaaaaccaaaagaacaagaatttcttggtaagaagccgggaa cagacaacagaagtcatgaagcccaagtgaaatcaaaggtgctaaatggtcgcccaggagacatccgttgtgcttgcctg cgttttggaagctctgaagtcacatcacaggacacggggcagtggcaaccttgtctctatgccagctcagtcccatcaga gagcgagcgctacccacttctaaatagcaatttcgccgttgaagaggaagggcaaaaccactagaactctccatcttatt ttcatgtatatgtgttcattaaagcatgaatggtatggaactctctccaccctatatgtagtataaagaaaagtaggttt acattcatctcattccaacttcccagttcaggagtcccaaggaaagccccagcactaacgtaaatacacaacacacacac tctaccctatacaactggacattgtctgcgtggttcctttctcagccgcttctgactgctgattctcccgttcacgttgc ctaataaacatccttcaagaactctgggctgctacccagaaatcattttacccttggctcaatcctctaagctaaccccc ttctactgagccttcagtcttgaatttctaaaaaacagaggccatggcagaataatctttgggtaacttcaaaacggggc agccaaacccatgaggcaatgtcaggaacagaaggatgaatgaggtcccaggcagagaatcatacttagcaaagttttac ctgtgcgttact attggcctctttaagagttagtttctttgggattgctatgaatgataccctgaatttggcctgcact aatttgatgtttacaggtggacacacaaggtgcaaatcaatgcgtacgtttcctgagaagtgtctaaaaacaccaaaaag ggatccgtacattcaatgtttatgcaaggaaggaaagaaagaaggaagtgaagagggagaagggatggaggtcacactgg tagaacgtaaccacggaaaagagcgcatcaggcctggcacggtggctcaggcctataaccccagctccctaggagaccaa ggcgggagcatctcttgaggccaggagtttgagaccagcctgggcagcatagcaagacacatccctacaaaaaattagaa attggctggatgtggtggcatacgcctgtagtcctagccactcaggaggctgaggcaggaggattgcttgagcccaggag ttcgaggctgcagtcagtcatgatggcaccactgcactccagcctgggcaacagagcaagatcctgtctttaaggaaaaa aagacaagggaattc (SEQ ID NO: 12287) gaattcatggaaatgggaagggcagtgatggagatgggaagggcagtgggggttggaggggtggggattgttgttgggta cgaaaacagaattagatcgaatgaataagatctagtatttgatagcataacagggtgactttagtcaacaataatttatt gtacatttaaaaataactaaaagagtatacttggattttaacacaaagaaaggataaatacttgaggtgatggatacccc atttaccctgatgtgattattatacattgtatgcctgtatcaaaatagctcatgtgcctcatgaatatagacacctacca catgcccacaaaattaaaaactaaaaaaaacagtcatctctgaatgctaaacggagtaaggggcttcctggaaggctggg tgaaatgggagtctcggaaagatggtgtgttgcaggctgggaggagggtgagacgctggggtcacctagagggacctgct tgtgtgaagcctacgtattagtgggtatgtgtgtgaccggatggaggcgtcagaggtgttgggtagcctgtgtgagttgg cgtgggggtgatgtaggaggggagagagggagggcctgcgttcccttggctcctgtgtgcagctaggcccctatttgaca atgtgtgtctgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgccgcccccagcgtaggaggcagatctttatctggc cctgggtgcttgaggagtttcaggctttctcataagcctcgtctccccgcctctccaccccaggccttgcccctctatcc tctgcacaggaagtgggctggctctgggcttttagtctttgcggccccagcagccagagctcagcagggccctggagaga tggccacggtcccagcaccggggaggactggagagcgcgcgctgccaccgccccatgtctcagccaggtgatgtccccct gcctccctcccggcccctgtggaccagccagagggctgggagtgaaagtcacagagaagactttcagctctgactcagtt cccccagcagtttctgcctgaactcccatcccccaactttgtcttagaattc (SEQ ID NO 12288) gaagagcaagcgccatgttgaagccatcattaccattcacatccctcttattcctgcagctgcccctgctgggagtgggg ctgaacacgacaattctgacgcccaatgggaatgaagacaccacagctgatttcttcctgaccactatgcccactgactc cctcagtgtttccactctgcccctcccagaggttcagtgttttgtgttcaatgtcgagtacatgaattgcacttggaaca gcagctctgagccccagcctaccaacctcactctgcattattggtacaagaactcggataatgataaagtccagaagtgc agccactatctattctctgaagaaatcacttctggctgtcagttgcaaaaaaaggagatccacctctaccaaacatttgt tgttcagctccaggacccacgggaacccaggagacaggccacacagatgctaaaactgcagaatctggtgatcccctggg ctccagagaacctaacacttcacaaactgagtgaatcccagctagaactgaactggaacaacagattcttgaaccactgt ttggagcacttggtgcagtaccggactgactgggaccacagctggactgaacaatcagtggattatagacataagttctc cttgcctagtgtggatgggcagaaacgctacacgtttcgtgttcggagccgctttaacccactctgtggaagtgctcagc attggagtgaatggagccacccaatccactgggggagcaatacttcaaaagagaatcctttcctgtttgcattggaagcc gtggttatctctgttggctccatgggattgattatcagccttctctgtgtgtatttctggctggaacggacgatgccccg aattcccaccctgaagaacctagaggatcttgttactgaataccacgggaacttttcggcctggagtggtgtgtctaagg gactggctgagagtctgcagccagactacagtgaacgactctgcctcgtcagtgagattcccccaaaaggaggggccctt ggggaggggcctggggcctccccatgcaaccagcatagcccctactgggcccccccatgttacaccctaaagcctgaaac ctgaaccccaatcctctgacagaagaaccccagggtcctgtagccctaagtggtactaactttccttcattcaacccacc tgcgtctcatactcacctcaccccactgtggctgatttggaattttgtgcccccatgtaagcaccccttcatttggcatt ccccacttgagaattacccttttgccccgaacatgtttttcttctccctcagtctggcccttccttttcgcaggattctt cctccctccctctttccctcccttcctctttccatctaccctccgattgttcctgaaccgatgagaaataaagtttctgt tgataatcatc (SEQ ID NO: 12289) gagagactggatggacccacaagggtgacagcccaggcggaccgatcttcccatcccacatcctccggcgcgatgccaaa aagaggctgacggcaactgggccttctgcagagaaagacctccgcttcactgccccggctggtcccaagggtcaggaaga tggattcatacctgctgatgtggggactgctcacgttcatcatggtgcctggctgccaggcagagctctgtgacgatgac ccgccagagatcccacacgccacattcaaagccatggcctacaaggaaggaaccatgttgaactgtgaatgcaagagagg tttccgcagaataaaaagcgggtcactctatatgctctgtacaggaaactctagccactcgtcctgggacaaccaatgtc aatgcacaagctctgccactcggaacacaacgaaacaagtgacacctcaacctgaagaacagaaagaaaggaaaaccaca gaaatgcaaagtccaatgcagccagtggaccaagcgagccttccaggtgaagagaagcctcaggcaagccccgaaggccg tcctgagagtgagacttcctgcctcgtcacaacaacagattttcaaatacagacagaaatggctgcaaccatggagacgt ccatatttacaacagagyaccaggtagcagtggccggctgtgttttcctgctgatcagcgtcctcctcctgagtgggctc acctggcagcggagacagaggaagagtagaagaacaatctagaaaaccaaaagaacaagaatttcttggtaagaagccgg gaacagacaacagaagtcatgaagcccaagtgaaatcaaaggtgctaaatggtcgcccaggagacatccgttgtgcttgc ctgcgttttggaagctctgaagtcacatcacaggacacggggcagtggcaaccttgtctctatgccagctcagtcccatc agagagcgagcgctacccacttctaaatagcaatttcgccgttgaagaggaagggcaaaaccactagaactctccatctt attttcatgtatatgtgttcattaaagcatgaatggtatggaactctctccaccctatatgtagtataaagaaaagtagg tttacattcatctcattccaacttcccagttcaggagtcccaaggaaagccccagcactaacgtaaatacacaacacaca cactctaccctatacaactggacattgtctgcgtggttcctttctcagccgcttctgactgctgattctcccgttcacgt tgcctaataaacatccttcaagaactctgggctgctacccagaaatcattttacccttggctcaatcctctaagctaacc cccttccactgagccttcagtcttgaatttctaaaaaacagaggccatggcagaataatctttgggtaacttcaaaacgg ggcagccaaacccatgaggcaatgtcaggaacagaaggatgaatgaggtcccaggcagagaatcatacttagcaaagttt tacctgtgcgttactaattggcctctttaagagttagtttctt (SEQ ID NO:12290) gaattctcaggatccttcagttcgccgcatccttctccattatttgaatattggaggctgcctgaccagaatcttgtcag gactttgctccttcatcccaggtggtcccggctgactcctgaggacgttacagccctgaggggaggactcagccttatga agtgctgggtgagaccactgccaagaagtgcttgctcaccctaccttcaacggcaggggaatctccctctccttttatgg gcgtagtgaagaaaggattcataaatgaagttcaatccttctcatcaaccccagcccacacctccagcaattgaacttga aaaaaaaaacctggtttgaaaaattaccgcaaactatattgtcatcaaaaaaaaaaaaaaaaaaacacttcctatatttg agatgagagaagagagtgctaggcagtttcctggctgaacacgccagcccaatacttaaagagagcaactcctgactccg atagagactggatggacccacaagggtgacagcccaggcggaccgatcttcccatcccacatcctccggcgcgatgccaa aaagaggctgacggcaactgggccttctgcagagaaagacctccgcttcactgccccggctggtcccaagggtcaggaag atggattcatacctgctgatgtggggactgctcacgttcatcatggtgcctggctgccaggcaggtaagggcctgtgggt gcccccggaattc (SEQ ID NO: 12291) gagctctgtgacgatgacccgccagagatcccacacgccacattcaaagccatggcctacaaggaaggaaccatgttgaa ctgtgaatgcaagagaggtttccgcagaataaaaagcgggtcactctatatgctctgtacaggaaactctagccactcgt cctgggacaaccaatgtcaatgcacaagctctgccactcggaacacaacgaaacaagtgacacctcaacctgaagaacag aaagaaaggaaaaccacagaaatgcaaagtccaatgcagccagtggaccaagcgagccttccaggtcactgcaaggaacc tccaccatgggaaaatgaagccacagagagaatttatcatttcgtggtggggcagatggtttattatcagtgcgtccagg gatacagggctctacacagaggtcctgctgagagcgtctgcaaaatgacccacgggaagacaaggtggacccagccccag ctcatatgcacaggtgaaatggagaccagtcagtttccaggtgaagagaagcctcaggcaagccccgaaggccgtcctga gagtgagacttcctgcctcgtcacaacaacagattttcaaatacagacagaaatggctgcaaccatggagacgtccatat ttacaacagagtaccaggtagcagtggccggctgtgttttcctgctgatcagcgtcctcctcctgagtgggctcacctgg cagcagagacagaggaagagtagaagaacaatctag (SEQ ID NO: 12292) gaattctcaggatccttcagttcgccgcatccttctccattatttgaatattggaggctgcctgaccagaatcttgtcag gactttgctccttcatcccaggtggtcccggctgactcctgaggacgttacagccctgagggaggactcagcttatgaag tgctgggtgagaccactgccaagaagtgcttgctcacctaccttcaacggcaggggaatctccctctccttttatgggcg tagctgaagaaaggattcataaatgaagttcaatccttctcatcaccccagcccaacctccagcaattgaacttgaaaaa aaaaacctggtttgaaaaattaccgcaaactatattgtcatcaaaaaaaaaaaaaaaaaaaaacacttcctatatttgag atgagagaagagagtgctaggcagtttcctggctgaacacgccagcccaatacttaaagagagcaactcctgactccgat agagactggatggacccacaagggtgacagcccaggcggaccgatcttcccatcccacatcctccggcgcgatgccaaaa agaggctgacggcaactgggccttctgcagagaaagacctccgcttcactgccccggctggtcccaagggtcaggaagat ggattcatacctgctgatgtggggactgctcacgttcatcatggtgcctggctgccaggcaggtaagggcc (SEQ ID NO: 12293) gaattcatgccacaactgagtgattttttttttctcaaacccaattccacaaagtaaaagcctgatgaaatacagtgaag gctgatgcttattaactgtgtttcccaaatccagagctctaaaaaggttctgcatacagtcattcattcaatgcttaacg actgagcattaattccatgctaagtactgaactcagcactaggaataagaaggcgacctagaggcatatcctctctctaa agatgcatagagcctcattggaatgatcagccgtgtctccagagagctacaaggcagttttcaattggtaaatgccctga gagtgatgggcttgtggcatgtgtaagggttagacagacctgggacctagacatgacaccactcctgacgaattatgtga gtgtgggtgtttcacaaccacaatgagatgcaatgcctgcacttgtaacatggaaatagtgatggcatgccccgcagatt gctgtgagaagtcagcggcagagacatgcaacattctcagcacagtgcttgccatgtagtaagggcctagtcagtgctag tgattcctttcaatattcctaagatgcagataagggaacagcccagaggagggggagcacttccagagggaggaatgcgg tgagacttccttcagcagggtagcactggagctgggtgttaaggagtgagtgagctttgggcttatggatttaacagagg aaaccaagaaaagaggaggcggtgttgcaggaacagtgagcagttgatgatttttattttgttctctggtctgcttggga acatttttgtggcaaagacagcatgaaggatagcgaagaattaatactgaagagataggccagggcaggttatgaaggat tttgaataccgggctaagaaatgtgggcttaatttcaaagacattatggacactcctaaaatgttacgttgtagataagg gaaaagtattcttccagaagattaaattggggctgggcacggtggctcacgcctgtgatcccagcactttgggaggcgaa gtgggcagatcacctgaggtcaggagtttgagatcagcctggccaacgtggtgaagccccatctctactgaaaaaaaaaa ttagccgggcatggtggtgggtgcctgtaatctcagctacttgggaggctgaagcaggagaatcacatgaacctgggagg cagaggttgcagtgagccaagattgcaccactgcattccagtgggcgacagagcaagactcagtcaaaaaaaaaaaaaga ttaaactggaagcaatgggtaagaatggtggagtggagagacacatttgagtgagggaagccagctgaaaagctgtacag acgtctagacaaaatgtgacacaagcatgccttcacctccctgcaaagaccacagaccactgagctccaaagggggtttg gaatccttgtcctgggccgccattggtaactcatcagtgctggcttgagagataaactctattatccatccctgaactaa aatcatgacagaagtggccagggagctttgctgctatccccccaggaaacacgtcctccactcaaatggaaagaggaccc tctgacaacatctgtgggacccaacagcactggtcaccacaagccacaaaatgttaacaaagtcagttttcaattgttag ggacggaggactcagttcatgattcatacaaaccaactgttctctcccagtgttttctgggtggcacaacccacaagtca acagtggcttgggaactagacatttgagtagagttgggttatttgattcatagtggattttggttttccacgggacccct gtgcccttgtctagtagaatctggtggaaattacaaactgcagaaattcaactcagtgccgcaataacaggatgcacctg tagatttcgtagaattagcagcagcattctttcaataccagtttgagagaaataaccctgtttgcatagtgccaactggg gcagaatctgaagtgtcttgcctgcctctcggccatgggaggcaccgatctcagcaacatctatccaaccgccatccact taacaagcaaagatggaaggccctcgtgctccaggctatcctgcaatggttca ttgcttttgatgggattatcactttg acagatgtgcttgcaattaactgggggctttctgcttccaatccaaattcccacaggtggatcactggctcttggggagc aaaaacccttctttgtttgtttttgcttctcccagagcctgggcagagctccccattcctggatcctacgttgatatgca ctgaattgaattatactaaagggtgcacccaagagtgcatgagctaagtaaaatgtaatttgtgggacctcatgtggaca tttcaggtccatgtgtacaagataaaggagagaaaatcctgggggacaccacaggcctgggaaaatgacctcctactaag cctaacaagaacatccagtacataaacagcaggctctctgcaaccgcttcggtccttccactgccacgctcccagaaagc aaagggttatctcctgttcggattttggctctgagaccacagctcagcacatcactcctctagagaaaagaaagtctaag atgagagagtgaggctgctttcatgtggtgccagcgtatagtgcagggcaggcctgattgctgaacggatccctgcagac gtgagcggtcacttccccttttgagggcccatttcttttcctctttgaggagactgtgagcgtcctcagtgcagggctat gttttagcttcttggctctcctcacaggttctagcataattctttgattaattgcagtcaacgtttattgatggattatg tgacagaggtgaaattctttgatctgggtttcagcttttcctttcccccactccctcctttttctttttttttttttttt tttttagaggcgaggtcttgctctgtggccctggctggagtgcagtggtgcaatcatagctcattgcagccttgacctcc tggggtcaagcgaacctcaacgtcttggcctcctgagtagctgggactataggcatgcgccaccacgctcagcttcacct tttcctttccttgtgctcccctggcagatatgctggtaaacaatgaaccagtcaagaggacagcaacaggaggaaaatgg gagaaaccccattattcgtggactaaacaggcttcccactagtcctggctcacagaggaagtcatgctccatgtttcaaa tgtcctcaaagctcgttcaactccaaaatgcatgaagacaaaatgggaattttactcaagatttttgtgggctgttgggg agaagagttaacattgcaaagcatattgcaaactcttatcttcaaatgattttaaaattttcttccaagctctttattat ttctccagagctgccctgctcttcccactctgggtcctttctctgccactctcctcagcatgacttctccctaatcggcc agcatttcttttattctatagagcaagttttcttgccctgggcacctctcatttgcatgttataccaccacaccaagtga gcctcagagcaccagtgttttaatccctgaaaacagtccttacgggattcagcacagaggtcctcttggcagcctgtagt ctccagagtgacacgtcctcaacagtcaaagtgagcaagctatggtgcccatcaccaagtggggctcaccatttccctct gcgttcacttctctcctaccttcttccttatcccatccttcctccttcctttttttttctgcattcaattattcatggtt attcatttcatacgggcatctgtgccacttggttctacaggcatttttttttttgagacagacttttgcccttgtccccc aggctggcgtgcagcggtgtgatcttggctcactgcaatctccacctcctaggttcaagcaagtctcctgccttagcctc ccaagtagctggaattacaggcatgtgccaccaagcccggcaaatttttgtatttttagtagagacagggtttcaccatg ttggccaggctggtctcaaactcctgacctcaggtgatctgcctgcctcggcctcccaaagtgctgggataacaggcgtg agccatcgtgctcggccggttctatgggcattgtggaagtgaccgttaacaagccccaagggtaagtaaaggaaaatgaa aggtgattgattcctcaccacctctccccttttttcctctactctttgcccctgctccccaatctagactctaataaaca gaaatgatttttgttgcaagctgaaaactcgttcttgtggttggggctaggggggtggcaagtcaagctttagagttgtc tggataataaatgctgtcttcaaggactgtccaacattgtaggaacaagagaacaacccaagtgaacaactaactcctgt tcacaaatgctactgcctctctgccatcccctaacctcagcctcacacacttgaatttcgccaatccatttgatgagctc aaatcagtgaattttctcctcgccaaagctcacaaattctgttccccgcttcttgccccacatccaggcattaccaactg cattttccctttgcctgatattctggcatcaagcctccttgccattccaatttatttcaccttcctccagtccttatgat ttccttcctgaagagtatttcagcatctctatgcctcaatcttccctgcacaccacaccagctcggcctcatcatcacat tacttggctatgtcccgcctgggttagacagcttcagtggctgaagtccatagatcttattctgtttttcgaggtccacc tgactctgaatccagctgacatttctgcccttagcttctacccctctctacttctggttaactatggaccacactctgct tcctcaggaaccacctaccaaggccgtatccatccttcaaggacaatacgtgggcctttcctgatcacatcagctcaaca acttttccctcctacatttcaattgctcttcttaccataatcattagtattcaccccactgtacgtctagaaagaaagtg gtcttaaacctaagggaaggcagtctaggtcagaaatttgttgtccgctgttctgagcagtttcttctaggaagtaccaa acatttctgataatagaattgagcaatttcctgatgaagtgagactcagcttgcactgttgaccggctgtcctggatgaa cctagttacttttaaccaaatgttcctttcttgaacttgttcctttcttgaacttaatctatcaatgttatctagataac tttcctcaaaaaaaaaaaaaaaaaaaaaaaccctctactaggaaagaaatctttgaaccggacttattggaaattacctc cttgcagcaggtttgaaacaaaactttgaatttgcctcacaaagaatttgtctgaaactgctttagtatatgctagttat atttgtatgcacatgtggcttcatacatagtggttggacacccatatgtgttatgcactttgttaggtgacgtaagttca cagataaactggaacatagggctatcctctagaggcccacagtttgacaccttaacctgagatccttggacctttgaagt tcagagtgcccacaaccgctgggtgtggtggctcacacttgtaatcccagtactctgcagggctgaggtgggaggatcgc ttgagtccaggagtctgagaccagcctgggcaacatgacaaaaccccatctctacaaaaattacaaaaaaaattagccag gcctggtggtgcatgcctgtggtcccagttacttgagaggctgaagtgggaggatcacttgagtcaaggaggtagaggct gcagtgagttgagatggcaacactgcactccagaaaccccatctcaaacaaaacagagcaaaacaaaacaaactgcccat aatgctcctgaaacttcctacggatttatccagagtatgtgctgatgtgcattttttccaaggagggaaaccaaaggttc tatcaaattaagaaaagagtttttaccattgtggaagacagtatggcgattcctcaagcatctaaaatcagaaataccat ttgacccagcaatcctattactgggtatatacccaaaggaatagaaatcattctactataaagtcacatgcaaccgtatg tttattgcagcactatttacaatagcaaaatggaaccaactgaaatgcccatcaatgagactagataaagaaaatgtgat acatatacaccatggaat ctatgcagccatgaaaaggaatgagatcacgtccttggcagggacatggatgaagctggaa gccattatcctcagcaaactaacacaggaacagaaaaccaaatgccgcatgttctcactcataagtgggagttgaacaat gacagcacatagacatagggaggggaacatcacacgccagggcctgctgcagggtggggggtggggtgtgaggggaggga acttagaagacaggtgagtaggtgcagcagaccaccatggcacacttatacctatgtaaccaacctgcacgttctacaca tgtatcctggaacttaaattaaaaacaaaaaagagtttttaatccaagaaagattaacagcaactagaagaaagaaagag atataaacagtgaattgcaatgcagcacggcaggtgttatgatggagtagaaaggactggaaaaggcctcctggaggaag ggacactcaagtgtctttccatttcacctgtaaactcattaagggcaaaagctttgctacagcttcagtatgagatcctg ggcaatccgtgacaaaatgggtctgcttttgcacccccaacttcttctcacatccctgcatcgtgccatgcagcatcaac tggaaacctcagcgtcagcaaacgacgacagagcgttcatccgtaaggtgaaccagaaaagccagttcaatgacttgttt aaccatggtccatctcagaaccaagagttgggcctcttatttaccagaaaaattgtgggggctttgtgatatggctttaa aaaaatcttgtaattgccaggcgtggtggctcacacctgtaatcccagcactttgggaggccgaggtgggtgaatcgcct aaggtcaggagttcgagaccagcctgaccaacatggtgaaactccgtctctactaaaaatacaaaaactagctggatgtg gtgacgcgtgcctgtaatcctagctactcaggaggctgacgcaggagaatcacttgaacctgggaggcagaggttgcagt gagccaagattgtgccattgcgctccaaaaaaaaaaaaaaaatacattaacataaatttaaatattttataatgacaatc cacattaactacttaaagcataagctattttccaggagaggcagcaagtgcattctactcccatgcccaagaagaaagga gcgtgactttggtgggagtactaggagtttctactggagcacttgcccgcagagtgagaaacgttcctagagaggaagtt atacctgctgtggaatttaagagaatcttgtcatattttgacaagttttttgagatggaagtctcactctgtcgcccagg ctggagtgcagtggcgcaatctcagctcactgcagcctgcacctcctcggttccagctattctcttgtctcagcctcctg agtaactgggattacaggcgcccgccactacgcctggctaatttttgtatttttagtagaaatggggttttaccatgttg gccagactggtctcaaactcccgacctcaggtgatctgcctgcctcagcctcccaaagtgctggaattacaggcgtgtgc cactgcgcctggctaatttttttttttttttttttttagtagagacggtggtttcaccatgtcatccaggctggtctcaa actcctgacctcaggtgatccacccaccttggtctaccaaagtgctcggattacaggcatgagccaccaggcccagtcaa cgtgatgtgttttggaaccctgaattccttggcttgccggagggttttctttttgttaatatctttgcttgctttctagt atttaaaaaattgtgttttgctctaactatgcaatggctttaagtcttagacaaatttccagggagcaaaacacactcaa ccaatttcataataatcagaagagagctctgatcaataaataagcaagactgaattttacaaaataatccaaagtttaaa accaaagcccactttttgcatgatcctttaagagaaagaaatctggaagcaaaacaccttataaaatgacaatgcacttt caggagcccagggcactgtggtgaaatgatgatggctagtacaggttataagccttggggaattatttatgaattctcag gatccttcagttcgccgcatccttctccattatttgaatattggaggctgcctgaccagaatcttgtcaggactttgctc ct catcccaggtggtcccggctgactcctgaggacgttacagccctgaggggaggactcagcttatgaagtgctgggtg agaccactgccaagaagtgcttgctcaccctaccttcaacggcaggggaatctccctctccttttatgggcgtagctgaa gaaaggattcataaatgaagttcaatccttctcatcaaccccagcccacacctccagcaattgaacttgaaaaaaaaaac ctggtttgaaaaattaccgcaaactatattgtcatcaaaaaaaaaaaaaaaaaaacacttcctatatttgagatgagaga agagagtgctaggcagtttcctggctgaacacgccagcccaatacttaaagagagcaactcctgactccgatagagactg gatggacccacaagggtgacagcccaggcggaccgatcttcccatcccacatcctccggcgcgatgccaaaaagaggctg acggcaactgggccttctgcagagaaagacctccgcttcactgccccggctggtcccaagggtcaggaagatggattcat acctgctgatgtggggactgctcacgttcatcatggtgcctggctgccaggcaggtaagggcctgtgggtgcccccggaa ttcgaattccccccccccccccccgagagactggatggacccacaagggtgacagcccaggcggaccgatcttcccatcc cacatcctccggcgcgatgccaaaaagaggctgacggcaactgggccttctgcagagaaagacctccgcttcactgcccc ggctggtcccaagggtcaggaagatggattcatacctgctgatgtggggactgctcacgttcatcatggtgcctggctgc caggcagagctctgtgacgatgacccgccagagatcccacacgccacattcaaagccatggcctacaaggaaggaaccat gttgaactgtgaatgcaagagaggtttccgcagaataaaaagcgggtcactctatatgctctgtacaggaaactctagcc actcgtcctgggacaaccaatgtcaatgcacaagctctgccactcggaacacaacgaaacaagtgacacctcaacctgaa gaacagaaagaaaggaaaaccacagaaatgcaaagtccaatgcagccagtggaccaagcgagccttccaggtcactgcag ggaacctccaccatgggaaaatgaagccacagagagaatttatcatttcgtggtggggcagatggtttattatcagtgcg tccagggatacagggctctacacagaggtcctgctgagagcgtctgcaaaatgacccacgggaagacaaggtggacccag ccccagctcatatgcacaggtgaaatggagaccagtcagtttccaggtgaagagaagcctcaggcaagccccgaaggccg tcctgagagtgagacttcctgcctcgtcacaacaacagattttcaaatacagacagaaatggctgcaaccatggagacgt ccatatttacaacagagtaccaggtagcagtggccggctgtgttttcctgctgatcagcgtcctcctcctgagtgggctc acctggcagcggagacagaggaagagtagaagaacaatctagaaaaσcaaaagaacaagaatttcttggtaagaagccgg gaacagacaacagaagtcatgaagcccaagtgaaatcaaaggtgctaaatggtcgcccaggagacatccgttgtgcttgc ctgcgttttggaagctctgaagtcacatcacaggacacggggcagtggcaaccttgtctctatgccagctcagtcccatc agagagcgagcgctacccacttctaaatagcaatttcgccgttgaagaggaagggcaaaaccactagaactctccatctt attttcatgtatatgtgttcattaaagcatgaatggtatggaactctctccaccctatatgtagtataaagaaaagtagg tttacattcatctcattccaacttcccagttcaggagtcccaaggaaagccccagcactaacgtaaatacacaacacaca cactctaccctatacaactggacattgtctgcgtggttcctttctcagccgcttctgactgctgattctcccgttcacgt tgcctaataaacatccttcaagaactctgggctgctacccagaaatcattttacccttggctcaatcctctaagctaacc cccttctactgagccttcagtcttgaatttctaaaaaacagaggccatggcagaataatctttgggtaacttcaaaacgg ggcagccaaacccatgaggcaatgtcaggaacagaaggatgaatgaggtcccaggcagagaatcatacttagcaaagttt tacctgtgcgttactaattggcctctttaagagttagtttctttgggattgctatgaatgataccctgaatttggcctgc actaatttgatgtttacaggtggacacacaaggtgcaaatcaatgcgtacgtttcctgagaagtgtctaaaaacaccaaa aagggatccgtacattcaatgtttatgcaaggaaggaaagaaagaaggaagtgaagagggagaagggatggaggtcacac tggtagaacgtaaccacggaaaagagcgcatcaggcctggcacggtggctcaggcctataaccccagctccctaggagac caaggcgggagcatctcttgaggccaggagtttgagaccagcctgggcagcatagcaagacacatccctacaaaaaatta gaaattggctggatgtggtggcatacgcctgtagtcctagccactcaggaggctgaggcaggaggattgcttgagcccag gagttcgaggctgcagtcagtcatgatggcaccactgcactccagcctgggcaacagagcaagatcctgtctttaaggaa aaaaagacaagggaattcgaattcatggaaatgggaagggcagtgatggagatgggaagggcagtgggggttggaggggt ggggattgttgttgggtacgaaaacagaattagatcgaatgaataagatctagtatttgatagcataacagggtgacttt agtcaacaataatttattgtacatttaaaaataactaaaagagtatacttggattttaacacaaagaaaggataaatact tgaggtgatggataccccatttaccctgatgtgattattatacattgtatgcctgtatcaaaatagctcatgtgcctcat gaatatagacacctaccacatgcccacaaaattaaaaactaaaaaaaacag catctctgaatgctaaacggagtaaggg gcttcctggaaggctgggtgaaatgggagtctcggaaagatggtgtgttgcaggctgggaggagggtgagacgctggggt cacctagagggacctgcttgtgtgaagcctacgtattagtgggtatgtgtgtgaccggatggaggcgtcagaggtgttgg gtagcctgtgtgagttggcgtgggggtgatgtaggaggggagagagggagggcctgcgttcccttggctcctgtgtgcag ctaggcccctatttgacaatgtgtgtctgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgccgcccccagcgtagga ggcagatctttatctggccctgggtgcttgaggagtttcaggctttctcataagcctcgtctccccgcctctccacccca ggccttgcccctctatcctctgcacaggaagtgggctggctctgggcttttagtctttgcggccccagcagccagagctc agcagggccctggagagatggccacggtcccagcaccggggaggactggagagcgcgcgctgccaccgccccatgtctca gccaggtgatgtccccctgcctccctcccggcccctgtggaccagccagagggctgggagtgaaagtcacagagaagact ttcagctctgactcagttcccccagcagtttctgcctgaactcccatcccccaactttgtcttagaattcgaagagcaag cgccatgttgaagccatcattaccattcacatccctcttattcctgcagctgcccctgctgggagtggggctgaacacga caattctgacgcccaatgggaatgaagacaccacagctgatttcttcctgaccactatgcccactgactccctcagtgtt tccactctgcccctcccagaggttcagtgttttgtgttcaatgtcgagtacatgaattgcacttggaacagcagctctga gccccagcctaccaacctcactctgcattattggtacaagaactcggataatgataaagtccagaagtgcagccactatc tattctctgaagaaatcacttctggctgtcagttgcaaaaaaaggagatccacctctaccaaacatttgttgttcagctc caggacccacgggaacccaggagacaggccacacagatgctaaaactgcagaatctggtgatcccctgggctccagagaa cctaacacttcacaaactgagtgaatcccagctagaactgaactggaacaacagattcttgaaccactgtttggagcact tggtgcagtaccggactgactgggaccacagctggactgaacaatcagtggattatagacataagttctccttgcctagt gtggatgggcagaaacgctacacgtttcgtgttcggagccgctttaacccactctgtggaagtgctcagcattggagtga atggagccacccaatccactgggggagcaatacttcaaaagagaatcctttcctgtttgcattggaagccgtggttatct ctgttggctccatgggattgattatcagccttctctgtgtgtatttctggctggaacggacgatgccccgaattcccacc ctgaagaacctagaggatcttgttactgaataccacgggaacttttcggcctggagtggtgtgtctaagggactggctga gagtctgcagccagactacagtgaacgactctgcctcgtcagtgagattcccccaaaaggaggggcccttggggaggggc ctggggcctccccatgcaaccagcatagcccctactgggcccccccatgttacaccctaaagcctgaaacctgaacccca atcctctgacagaagaaccccagggtcctgtagccctaagtggtactaactttccttcattcaacccacctgcgtctcat actcacctcaccccactgtggctgatttggaattttgtgcccccatgtaagcaccccttcatttggcattccccacttga gaattacccttttgccccgaacatgtttttcttctccctcagtctggcccttccttttcgcaggattcttcctccctccc tctttccctcccttcctctttccatctaccctccgattgttcctgaaccgatgagaaataaagtttctgttgataatcat cgagagactggatggacccacaagggtgacagcccaggcggaccgatcttcccatcccacatcctccggcgcgatgccaa aaagaggctgacggcaactgggccttctgcagagaaagacctccgcttcactgccccggctggtcccaagggtcaggaag atggattcatacctgctgatgtggggactgctcacgttcatcatggtgcctggctgccaggcagagctctgtgacgatga cccgccagagatcccacacgccacattcaaagccatggcctacaaggaaggaaccatgttgaactgtgaatgcaagagag gtttccgcagaataaaaagcgggtcactctatatgctctgtacaggaaactctagccactcgtcctgggacaaccaatgt caatgcacaagctctgccactcggaacacaacgaaacaagtgacacctcaacctgaagaacagaaagaaaggaaaaccac agaaatgcaaagtccaatgcagccagtggaccaagcgagccttccaggtgaagagaagcctcaggcaagccccgaaggcc gtcctgagagtgagacttcctgcctcgtcacaacaacagattttcaaatacagacagaaatggctgcaaccatggagacg tccatatttacaacagagyaccaggtagcagtggccggctgtgttttcctgctgatcagcgtcctcctcctgagtgggct cacctggcagcggagacagaggaagagtagaagaacaatctagaaaaccaaaagaacaagaatttcttggtaagaagccg ggaacagacaacagaagtcatgaagcccaagtgaaatcaaaggtgctaaatggtcgcccaggagacatccgttgtgcttg cctgcgttttggaagctctgaagtcacatcacaggacacggggcagtggcaaccttgtctctatgccagctcagtcccat cagagagcgagcgctacccacttctaaatagcaatttcgccgttgaagaggaagggcaaaaccactagaactctccatct tattttcatgtatatgtgttcattaaagcatgaatggtatggaactctctccaccctatatgtagtataaagaaaagtag gtttacattcatctcattccaacttcccagttcaggagtcccaaggaaagccccagcactaacgtaaatacacaacacac acactctaccctatacaactggacattgtctgcgtggttcctttctcagccgcttctgactgctgattctcccgttcacg ttgcctaataaacatccttcaagaactctgggctgctacccagaaatcattttacccttggctcaatcctctaagctaac ccccttccactgagccttcagtcttgaatttctaaaaaacagaggccatggcagaataatctttgggtaacttcaaaacg gggcagccaaacccatgaggcaatgtcaggaacagaaggatgaatgaggtcccaggcagagaatcatacttagcaaagtt ttacctgtgcgttactaattggcctctttaagagttagtttcttgaattctcaggatccttcagttcgccgcatccttct ccattatttgaatattggaggctgcctgaccagaatcttgtcaggactttgctccttcatcccaggtggtcccggctgac tcctgaggacgttacagccctgaggggaggactcagccttatgaagtgctgggtgagaccactgccaagaagtgcttgct caccctaccttcaacggcaggggaatctccctctccttttatgggcgtagtgaagaaaggattcataaatgaagttcaat ccttctcatcaaccccagcccacacctccagcaattgaacttgaaaaaaaaaacctggtttgaaaaattaccgcaaacta tattgtcatcaaaaaaaaaaaaaaaaaaacacttcctatatttgagatgagagaagagagtgctaggcagtttcctggct gaacacgccagcccaatacttaaagagagcaactcctgactccgatagagactggatggacccacaagggtgacagccca ggcggaccgatcttcccatcccacatcctccggcgcgatgccaaaaagaggctgacggcaactgggccttctgcagagaa agacctccgcttcactgccccggctggtcccaagggtcaggaagatggattca cctgctgatgtggggactgctcacg ttcatcatggtgcctggctgccaggcaggtaagggcctgtgggtgcccccggaattcgagctctgtgacgatgacccgcc agagatcccacacgccacattcaaagccatggcctacaaggaaggaaccatgttgaactgtgaatgcaagagaggtttcc gcagaataaaaagcgggtcactctatatgctctgtacaggaaactctagccactcgtcctgggacaaccaatgtcaatgc acaagctctgccactcggaacacaacgaaacaagtgacacctcaacctgaagaacagaaagaaaggaaaaccacagaaat gcaaagtccaatgcagccagtggaccaagcgagccttccaggtcactgcaaggaacctccaccatgggaaaatgaagcca cagagagaatt atcatttcgtggtggggcagatggtttattatcagtgcgtccagggatacagggctctacacagaggt cctgctgagagcgtctgcaaaatgacccacgggaagacaaggtggacccagccccagctcatatgcacaggtgaaatgga gaccagtcagtttccaggtgaagagaagcctcaggcaagccccgaaggccgtcctgagagtgagacttcctgcctcgtca caacaacagattttcaaatacagacagaaatggctgcaaccatggagacgtccatatttacaacagagtaccaggtagca gtggccggctgtgttttcctgctgatcagcgtcctcctcctgagtgggctcacctggcagcagagacagaggaagagtag aagaacaatctaggaattctcaggatccttcagttcgccgcatccttctccattatttgaatattggaggctgcctgacc agaatcttgtcaggactttgctccttcatcccaggtggtcccggctgactcctgaggacgttacagccctgagggaggac tcagcttatgaagtgctgggtgagaccactgccaagaagtgcttgctcacctaccttcaacggcaggggaatctccctct ccttttatgggcgtagctgaagaaaggattcataaatgaagttcaatccttctcatcaccccagcccaacctccagcaat tgaacttgaaaaaaaaaacctggtttgaaaaattaccgcaaactatattgtcatcaaaaaaaaaaaaaaaaaaaaacact tcctatatttgagatgagagaagagagtgctaggcagtttcctggctgaacacgccagcccaatacttaaagagagcaac tcctgactccgatagagactggatggacccacaagggtgacagcccaggcggaccgatcttcccatcccacatcctccgg cgcgatgccaaaaagaggctgacggcaactgggccttctgcagagaaagacctccgcttcactgccccggctggtcccaa gggtcaggaagatggattcatacctgctgatgtggggactgctcacgttcatcatggtgcctggctgccaggcaggtaag ggcc (SEQ ID NO:12294) aagcttaatataaacaagtttcttgtcactgccaccaccacgaccaaaaaaagctaatcaatcactata ataatacata tatatactatatataataaatatatatactatatataatacatatatacactatatataatacatatatactatatatac acta atactatatatacacatatatattatgaatgtatatatatagtatatatagtatatatactatgtatgtatatat agtatatatagtatatatactatgtatgatatat gtatatatagtatatatactatgtatgtgtatatatagtatatat agtatatatagta atatactatgtatgtatatatatagtatatatagtatatatactgtgtatgtatatatatagtata tatatactatatatgcatacatagtatatatgcatatatactatatatactatatatttatatatactatatactatata tactatatactgtatatatactatatatgtatgtatacgatatatatatatactatatatgtac (SEQ ID NO:12295) cagagaagctctatctcccctccaggagcccagctatgaactccttctccacaagcgccttcggtccagttgccttctcc ctggggctgctcctggtgttgcctgctgccttccctgccccagtacccccaggagaagattccaaagatgtagccgcccc acacagacagccactcacctcttcagaacgaattgacaaacaaattcggtacatcctcgacggcatctcagccctgagaa aggagacatgtaacaagagtaacatgtgtgaaagcagcaaagaggcactggcagaaaacaacctgaaccttccaaagatg gctgaaaaagatggatgcttccaatctggattcaatgaggagacttgcctggtgaaaatcatcactggtcttttggagtt tgaggtatacctagagtacctccagaacagatttgagagtagtgaggaacaagccagagctgtgcagatgagtacaaaag tcctgatccagttcctgcagaaaaaggcaaagaatctagatgcaataaccacccctgacccaaccacaaatgccagcctg ctgacgaagctgcaggcacagaaccagtggctgcaggacatgacaactcatctcattctgcgcagctttaaggagttcct gcagtccagcctgagggctcttcggcaaatgtagcatgggcacctcagattgttgttgttaatgggcattccttcttctg gtcagaaacctgtccactgggcacagaacttatgttgttctctatggagaactaaaagtatgagcgttaggacactattt taattatttttaatttattaatatttaaatatgtgaagctgagttaatttatgtaagtgatatttatattttaagaagta ccacttgaaacattttatgtattagttttgaaataataatggaaagtggctatgcagtttgaatatcctttgtttcagag ccagatcatttcttggaaagtgtacgcttacctcaaataaatggctaact atacatatttttaaagaaatatttatatt gtatttatataatgtataaaatggtttttataccaataaatggcattttaaaaaattcagca (SEQ ID NO: 12296) gaattccgggaacgaaagagaagctctatctcccctccaggagcccagctatgaactccttctccacaagcgccttcggt ccagttgccttctccctggggctgctcctggtgttgcctgctgccttccctgccccagtacccccaggagaagattccaa agatgtagccgccccacacagacagccactcacctcttcagaacgaattgacaaacaaattcggtacatcctcgacggca tctcagccctgagaaaggagacatgtaacaagagtaacatgtgtgaaagcagcaaagaggcactggcagaaaacaacctg aaccttccaaagatggctgaaaaagatggatgcttccaatctggattcaatgaggagacttgcctggtgaaaatcatcac tggtcttttggagtttgaggtatacctagagtacctccagaacagatttgagagtagtgaggaacaagccagagctgtgc agatgagtacaaaagtcctgatccagttcctgcagaaaaaggcaaagaatctagatgcaataaccacccctgacccaacc acaaatgccagcctgctgacgaagctgcaggcacagaaccagtggctgcaggacatgacaactcatctcattctgcgcag ctttaaggagttcctgcagtccagcctgagggctcttcggcaaatgtagcatgggcacctcagattgttgttgttaatgg gcattccttcttctggtcagaaacctgtccactgggcacagaacttatgttgttctctatggagaactaaaagtatgagc gttaggacactattttaattatttttaatttattaatatttaaatatgtgaagctgagttaatttatgtaagtcatattt atatttttaagaagtaccacttgaaacattttatgtattagttttgaaataataatggaaagtggctatgcagtttgaat atcctttgtttcagagccagatcatttcttggaaagtgtaggcttacctcaaataaatggctaacttatacatattttta aagaaatatttatattgtatttatataatgtataaatggtttttataccaataaatggcattttaaaaaattc (SEQ ID NO: 12297) aagcttaatataaacaagtttcttgtcactgccaccaccacgaccaaaaaaagctaatcaatcactatatataatacata tatatactatatataataaatatatatactatatataatacatat tacactatatataatacatatatactatatatac actatatactatatatacacatatatattatgaatgtatatatatagtatatatagtatatatactatgtatgtata at agtatatatagtatatatactatgtatgatatatagtatatatagtatatatactatgtatgtgtatatatagtatatat agtatatatagtatatatactatgtatgtatatatatagtatatatagtatatatactgtgtatgtatatatatagtata tatatactatatatgcatacatagtatatatgcatatatactatatatactatatatttatatatactatatactatata tactatatactgtatatatactatatatgtatgtatacgatatatatatatactatatatgtaccagagaagctctatct cccctccaggagcccagctatgaactccttctccacaagcgccttcggtccagttgccttctccctggggctgctcctgg tgttgcctgctgccttccctgccccagtacccccaggagaagattccaaagatgtagccgccccacacagacagccactc acctcttcagaacgaattgacaaacaaattcggtacatcctcgacggcatctcagccctgagaaaggagacatgtaacaa gagtaacatgtgtgaaagcagcaaagaggcactggcagaaaacaacctgaaccttccaaagatggctgaaaaagatggat gcttccaatctggattcaatgaggagacttgcctggtgaaaatcatcactggtcttttggagtttgaggtatacctagag tacctccagaacagatttgagagtagtgaggaacaagccagagctgtgcagatgagtacaaaagtcctgatccagttcct gcagaaaaaggcaaagaatctagatgcaataaccacccctgacccaaccacaaatgccagcctgctgacgaagctgcagg cacagaaccagtggctgcaggacatgacaactcatctcattctgcgcagctttaaggagttcctgcagtccagcctgagg gctcttcggcaaatgtagcatgggcacctcagattgttgttgttaatgggcattccttcttctggtcagaaacctgtcca ctgggcacagaacttatgttgttctctatggagaactaaaagtatgagcgttaggacactattttaattatttttaattt attaatatttaaatatgtgaagctgagttaatttatgtaagtgatatttatattttaagaagtaccacttgaaacatttt atgtattagttttgaaataataatggaaagtggctatgcagtttgaatatcctttgtttcagagccagatcatttcttgg aaagtgtacgcttacctcaaataaatggctaacttatacatatttttaaagaaatatttatattgtatttatataatgta taaaatggtttttataccaataaatggcattttaaaaaattcagcagaattccgggaacgaaagagaagctctatctccc ctccaggagcccagctatgaactccttctccacaagcgccttcggtccagttgccttctccctggggctgctcctggtgt tgcctgctgccttccctgccccagtacccccaggagaagattccaaagatgtagccgccccacacagacagccactcacc tcttcagaacgaattgacaaacaaattcggtacatcctcgacggcatctcagccctgagaaaggagacatgtaacaagag taacatgtgtgaaagcagcaaagaggcactggcagaaaacaacctgaaccttccaaagatggctgaaaaagatggatgct tccaatctggattcaatgaggagacttgcctggtgaaaatcatcactggtcttttggagtttgaggtatacctagagtac ctccagaacagatttgagagtagtgaggaacaagccagagctgtgcagatgagtacaaaagtcctgatccagttcctgca gaaaaaggcaaagaatctagatgcaataaccacccctgacccaaccacaaatgccagcctgctgacgaagctgcaggcac agaaccagtggctgcaggacatgacaactcatctcattctgcgcagctttaaggagttcctgcagtccagcctgagggct cttcggcaaatgtagcatgggcacctcagattgttgttgttaatgggcattccttcttctggtcagaaacctgtccactg ggcacagaacttatgttgttctctatggagaactaaaagtatgagcgttaggacactattttaattatttttaatttatt aatatttaaatatgtgaagctgagttaatttatgtaagtcatatttatatttttaagaagtaccacttgaaacattttat gtattagttttgaaataataatggaaagtggctatgcagtttgaatatcctttgtttcagagccagatcatttcttggaa agtgtaggcttacctcaaataaatggctaacttatacatatttttaaagaaatatttatattgtatttatataatgtata aatggtttttataccaataaatggcattttaaaaaattc (SEQ ID NO: 12298) ggatcctcctgcaagagacaccatcctgaggggaagagggcttctgaaccagcttgacccaataagaaattcttgggtgc cgacggggacagcagattcagagcctagagccgtgcctgcgtccgtagtttccttctagcttctttttgatttcaaatca agacttacagggagagggagcgataaacacaaactctgcaagatgccacaaggtcctcctttgacatccccaacaaagaa ggtgagtagtaatctccccctttctgccctgaaccaagtggcttcagtaagtttcagggctccaggagacctgggcatgc aggtgccgatgaaacagtggtgaagagactcagtggcagtggcagtggggagagcactcgcagcacaggcaaacctctgg cacaagagcaaagtcctcactggaggattcccaagggtcacttgggagagggcaggcagcagccaacctcctctaagtgg gctgaagcaggtgaagaaatggcagaagacgcggtggtggcaaaaaggagtcacacactccacctggagacgccttgaag taactgcacgaaatttgagggtggccaggcagttctacaacagccgcctcacagggagagccagaacacagcaagaactc agatgactggtagtattaccttcttcataatcccaggcttggggggctgcgatggagtcagaggaaactcagttcagaac atctttggtttttacaatacaaattaactggaacgctaaattctagcctgttaatctggtcactgaaaaaaaaaaaattt tttttttttcaaaaaacatagctttagcttattttttttttctctttgtaaaacttcgtgcatgacttcagctttactct tgtcaagacatgccaagtgctgagtcactaataaagaaaaaagaagtaaaggaagagtggttctgcttcttagcgctagc ctcaatgacgacctaagctgcacttttccccctagttgtgtcttgcgatgctaaaggacgtcattgcacaatcttaataa ggtttccaatcagccccacccgctctggccccaccctcaccctccaacaaagatttatcaaatgtgggattttcccatga gtctcaatattagagtctcaacccccaataaatataggactggagatgtctctgaggctcattctgccctcgag (SEQ ID NO: 12299) ggcggtcccctgttctccccgctcaggtgcggcgctgtggcaggaagccaccccctcggtcggccggtgcgcggggctgt tgcgccatccgctccggctttcgtaaccgcaccctgggacggcccagagacgctccagcgcgagttcctcaaatgttttc ctgcgttgccaggaccgtccgccgctctgagtcatgtgcgagtgggaagtcgcactgacactgagccgggccagagggag aggagccgagcgcggcgcggggccgagggactcgcagtgtgtgtagagagccgggctcctgcggatgggggctgcccccg gggcctgagcccgcctgcccgcccaccgccccgccccgcccctgccacccctgccgcccggttcccattagcctgtccgc ctctgcgggaccatggagtggtagccgaggaggaagcatgctggccgtcggctgcgcgctgctggctgccctgctggccg cgccgggagcggcgctggccccaaggcgctgccctgcgcaggaggtggcaagaggcgtgctgaccagtctgccaggagac agcgtgactctgacctgcccgggggtagagccggaagacaatgccactgttcactgggtgctcaggaagccggctgcagg ctcccaccccagcagatgggctggcatgggaaggaggctgctgctgaggtcggtgcagctccacgactctggaaactatt catgctaccgggccggccgcccagctgggactgtgcacttgctggtggatgttccccccgaggagccccagctctcctgc ttccggaagagccccctcagcaatgttgtttgtgagtggggtcctcggagcaccccatccctgacgacaaaggctgtgct cttggtgaggaagtttcagaacagtccggccgaagacttccaggagccgtgccagtattcccaggagtcccagaagttct cctgccagttagcagtcccggagggagacagctctttctacatagtgtccatgtgcgtcgccagtagtgtcgggagcaag ttcagcaaaactcaaacctttcagggttgtggaatcttgcagcctgatccgcctgccaacatcacagtcactgccgtggc cagaaacccccgctggctcagtgtcacctggcaagacccccactcctggaactcatctttctacagactacggtttgagc tcagatatcgggctgaacggtcaaagacattcacaacatggatggtcaaggacctccagcatcactgtgtcatccacgac gcctggagcggcctgaggcacgtggtgcagcttcgtgcccaggaggagttcgggcaaggcgagtggagcgagtggagccc ggaggccatgggcacgccttggacagaatccaggagtcctccagctgagaacgaggtgtccacccccatgcaggcactta ctactaataaagacgatgataatattctcttcagagattctgcaaatgcgacaagcctcccagtgcaagattcttcttca gtaccactgcccacattcctggttgctggagggagcctggccttcggaacgctcctctgcattgccattgttctgaggtt caagaagacgtggaagctgcgggctctgaaggaaggcaagacaagcatgcatccgccgtactctttggggcagctggtcc cggagaggcctcgacccaccccagtgcttgttcctctcatctccccaccggtgtcccccagcagcctggggtctgacaat acctcgagccacaaccgaccagatgccagggacccacggagcccttatgacatcagcaatacagactacttcttccccag atagctggctgggtggcaccagcagcctggaccctgtggatgacaaaacacaaacgggctcagcaaaagatgcttctcac tgccatgccagcttatctcaggggtgtgcggcctttggcttcacggaagagccttgcggaaggttctacgccaggggaaa atcagcctgctccagctgttcagctggttgaggtttcaaacctccctttccaaatgcccagcttaaaggggttagagtga acttgggccactgtgaagagaaccatatcaagactctttggacactcacacggacactcaaaagctgggcaggttggtgg gggcctcggtgtggagaagcggctggcagcccacccctcaacacctctgcacaagctgcaccctcaggcaggtgggatgg atttccagccaaagcctcctccagccgccatgctcctggcccactgcatcgtttca cttccaactcaaactcttaaaac ccaagtgcccttagcaaattctgtttttctaggcctggggacggcttttacttaaacgccaaggcctgggggaagaagct ctctcctccctttcttccctacagttcaaaaacagctgagggtgagtgggtgaataatacagtatgtcagggcctggtcg ttttcaacagaattataattagttcctcattagcagttttgcctaaatgtgaatgatgatcctaggcatttgctgaatac agaggcaactgcattggctttgggttgcaggacctcaggtgagaagcagaggaaggagaggagaggggcacagggtctct accatcccctgtagagtgggagctgagtgggggatcacagcctctgaaaaccaatgttctctcttctccacctcccacaa aggagagctagcagcagggagggcttctgccatttctgagatcaaaacggttttactgcagctttgtttgttgtcagctg aacctgggtaactagggaagataatattaaggaagacaatgtgaaaagaaaaatgagcctggcaagaatgcgtttaaact tggtttttaaaaaactgctgactgttttctcttgagagggtggaatatccaatattcgctgtgtcagcatagaagtaact tacttaggtgtgggggaagcaccataactttgtttagcccaaaaccaagtcaagtgaaaaaggaggaagagaaaaaatat tttcctgccaggcatggaggcccacgcacttcgggaggtcgaggcaggaggatcacttgagtccagaagtttgagatcag cctgggcaatgtgataaaaccccatctctacaaaaagcataaaaattagccaagtgtggtagagtgtgcctgaagtccca gatacttggggggctgaggtgggaggatctcttgagcctgggaggtcaaggctgcagtgagccgagattgcaccactgca ctccagcctggggtgacagagcaagtgagaccctgtctc (SEQ ID NO: 12300) ggatcctcctgcaagagacaccatcctgaggggaagagggcttctgaaccagcttgacccaataagaaattcttgggtgc cgacggggacagcagattcagagcctagagccgtgcctgcgtccgtagtttccttctagcttctttttgatttcaaatca agacttacagggagagggagcgataaacacaaactctgcaagatgccacaaggtcctcctttgacatccccaacaaagaa ggtgagtagtaatctccccctttctgccctgaaccaagtggcttcagtaagtttcagggctccaggagacctgggcatgc aggtgccgatgaaacagtggtgaagagactcagtggcagtggcagtggggagagcactcgcagcacaggcaaacctctgg cacaagagcaaagtcctcactggaggattcccaagggtcacttgggagagggcaggcagcagccaacctcctctaagtgg gctgaagcaggtgaagaaatggcagaagacgcggtggtggcaaaaaggagtcacacactccacctggagacgccttgaag taactgcacgaaatttgagggtggccaggcagttctacaacagccgcctcacagggagagccagaacacagcaagaactc agatgactggtagtattaccttcttcataatcccaggcttggggggctgcgatggagtcagaggaaactcagttcagaac atctttggtttttacaatacaaattaactggaacgctaaattctagcctgttaatctggtcactgaaaaaaaaaaaattt tttttttttcaaaaaacatagctttagcttattttttttttctctttgtaaaacttcgtgcatgacttcagctttactct tgtcaagacatgccaagtgctgagtcactaataaagaaaaaagaagtaaaggaagagtggttctgcttcttagcgctagc ctcaatgacgacctaagctgcacttttccccctagttgtgtcttgcgatgctaaaggacgtcattgcacaatcttaataa ggtttccaatcagccccacccgctctggccccaccctcaccctccaacaaagatttatcaaatgtgggattttcccatga gtctcaatattagagtctcaacccccaataaatataggactggagatgtctctgaggctcattctgccctcgagggcggt cccctgttctccccgctcaggtgcggcgctgtggcaggaagccaccccctcggtcggccggtgcgcggggctgttgcgcc atccgctccggctttcgtaaccgcaccctgggacggcccagagacgctccagcgcgagttcctcaaatgttttcctgcgt tgccaggaccgtccgccgctctgagtcatgtgcgagtgggaagtcgcactgacactgagccgggccagagggagaggagc cgagcgcggcgcggggccgagggactcgcagtgtgtgtagagagccgggctcctgcggatgggggctgcccccggggcct gagcccgcctgcccgcccaccgccccgccccgcccctgccacccctgccgcccggttcccattagcctgtccgcctctgc gggaccatggagtggtagccgaggaggaagcatgctggccgtcggctgcgcgctgctggctgccctgctggccgcgccgg gagcggcgctggccccaaggcgctgccctgcgcaggaggtggcaagaggcgtgctgaccagtctgccaggagacagcgtg actctgacctgcccgggggtagagccggaagacaatgccactgttcactgggtgctcaggaagccggctgcaggctccca ccccagcagatgggctggcatgggaaggaggctgctgctgaggtcggtgcagctccacgactctggaaactattcatgct accgggccggccgcccagctgggactgtgcacttgctggtggatgttccccccgaggagccccagctctcctgcttccgg aagagccccctcagcaatgttgtttgtgagtggggtcctcggagcaccccatccctgacgacaaaggctgtgctcttggt gaggaagtttcagaacagtccggccgaagacttccaggagccgtgccagtattcccaggagtcccagaagttctcctgcc agttagcagtcccggagggagacagctctttctacatagtgtccatgtgcgtcgccagtagtgtcgggagcaagttcagc aaaactcaaacctttcagggttgtggaatcttgcagcctgatccgcctgccaacatcacagtcactgccgtggccagaaa cccccgctggctcagtgtcacctggcaagacccccactcctggaactcatctttctacagactacggtttgagctcagat atcgggctgaacggtcaaagacattcacaacatggatggtcaaggacctccagcatcactgtgtcatccacgacgcctgg agcggcctgaggcacgtggtgcagcttcgtgcccaggaggagttcgggcaaggcgagtggagcgagtggagcccggaggc catgggcacgccttggacagaatccaggagtcctccagctgagaacgaggtgtccacccccatgcaggcacttactacta a aaagacgatgataatattctcttcagagattctgcaaatgcgacaagcctcccagtgcaagattcttcttcagtacca ctgcccacattcctggttgctggagggagcctggccttcggaacgctcctctgcattgccattgttctgaggttcaagaa gacgtggaagctgcgggctctgaaggaaggcaagacaagcatgcatccgccgtactctttggggcagctggtcccggaga ggcctcgacccaccccagtgcttgttcctctcatctccccaccggtgtcccccagcagcctggggtctgacaatacctcg agccacaaccgaccagatgccagggacccacggagcccttatgacatcagcaatacagactacttcttccccagatagct ggctgggtggcaccagcagcctggaccctgtggatgacaaaacacaaacgggctcagcaaaagatgcttctcactgccat gccagcttatctcaggggtgtgcggcctttggcttcacggaagagccttgcggaaggttctacgccaggggaaaatcagc ctgctccagctgttcagctggttgaggtttcaaacctccctttccaaatgcccagcttaaaggggttagagtgaacttgg gccactgtgaagagaaccatatcaagactctttggacactcacacggacactcaaaagctgggcaggttggtgggggcct cggtgtggagaagcggctggcagcccacccctcaacacctctgcacaagctgcaccctcaggcaggtgggatggatttcc agccaaagcctcctccagccgccatgctcctggcccactgcatcgtttcatcttccaactcaaactcttaaaacccaagt gcccttagcaaattctgtttttctaggcctggggacggcttttacttaaacgccaaggcctgggggaagaagctctctcc tccctttcttccctacagttcaaaaacagctgagggtgagtgggtgaataatacagtatgtcagggcctggtcgttttca acagaattataattagttcctcattagcagttttgcctaaatgtgaatgatgatcctaggcatttgctgaatacagaggc aactgcattggctttgggttgcaggacctcaggtgagaagcagaggaaggagaggagaggggcacagggtctctaccatc ccctgtagagtgggagctgagtgggggatcacagcctctgaaaaccaatgttctctcttctccacctcccacaaaggaga gctagcagcagggagggcttctgccatttctgagatcaaaacggttttactgcagctttgtttgttgtcagctgaacctg ggtaactagggaagataatattaaggaagacaatgtgaaaagaaaaatgagcctggcaagaatgcgtttaaacttggttt ttaaaaaactgctgactgttttctcttgagagggtggaatatccaatattcgctgtgtcagcatagaagtaacttactta ggtgtgggggaagcaccataactttgtttagcccaaaaccaagtcaagtgaaaaaggaggaagagaaaaaatattttcct gccaggcatggaggcccacgcacttcgggaggtcgaggcaggaggatcacttgagtccagaagtttgagatcagcctggg caatgtgataaaaccccatctctacaaaaagcataaaaattagccaagtgtggtagagtgtgcctgaagtcccagatact tggggggctgaggtgggaggatctcttgagcctgggaggtcaaggctgcagtgagccgagattgcaccactgcactccag cctggggtgacagagcaagtgagaccctgtctc (SEQ ID NO:12301) atacctaggcactaatttagttccatatgtactatgtgtacctgaaaagttgtgtggcaatcaaattttcacaaatagaa tcctgttttaaatacactaagaaagtacctactttatcctttaaacaagaggtcagcagactttttctacaaagggtcag atagtaaagattttacaccttttgtacaatacaatctctatctcatctacttagctctgccattgttgcataaaagcagc tgtagatgatacacaaatgggtgaggctgtattccaaatgaaacgttatttgcaaaaacaggtggtagattaaatttggt cccaaggcttacttgggaaaaaaaaagatcttttgaaaaagaaaaaataaatgaataatttttttaaaaaattgttccct aggtcatagtttgccagcccctgccctaaacaaataattcttgaatgcctactgtggtgtgtaagatatgagtaaatacc agggatacacagagaacaaaagagaaaaactgctattcttgtgaaacttggaagttggaggtaagctatttaaaataaac ccacaataaagtacttcacatagtgcagactgtttctttaaatcaaaactcactccaaacaaccaattgattcactttgt aagtttgaatttttgtcttcagattcttttaaagtgggcccttagtcaggagcggtggctcatgcctgtagtcctagcac tttgggaggctgaggcaggcagatcacttgaggtcaggagttcgagacaagcctggccaacatggcgaaaccccgtctcc actgaaaacacaaaaattaggctggcatagtggcatttgcctgtagtcctagctactcaggaggctgaggcaggagaatt gcttgaacctgggaggtgaaaattgcagtgagccgagatcatgctattgtac ccagcctgggcaacaaagcaagactcg tctcaaaaaaataaaaattaaaaaaataaagtagcctctagcctaagatagcttgagcctaggtgtgaatctactgcctt actctgatgtaagcacagtaagtgtgggggctgcagggaatatccaggaggaacaataatttcagaggctctgtctcttc atgtccttgacctctgcttacagcagcaatacttttactcagacttcctgtttctggaacttgccttcttttttgctgtg tttatacttcccttgtctgtggttagataagtataaagccctagatctaagcttctctgtcttcctccctccctcccttc ctcttactctcattcatttcatacacactggctcacacatctactctctctctctatctctctcagaatgacaattctag gtacaacttttggcatggttttttctttacttcaagtcgtttctggagaaagtggctatgctcaaaatggtgagtcattt ctaacttttcttatggattttggattatctgtagcatggtttcaggttattcagttccctaagagacctgagtcaggcac tgggtttgagtgc (SEQ ID NO-.12302) ctctctctctatctctctcagaatgacaattctaggtacaacttttggcatggttttttctttacttcaagtcgtttctg gagaaagtggctatgctcaaaatggagacttggaagatgcagaactggatgactactcattctcatgctatagccagttg gaagtgaatggatcgcagcattcactgacctgtgcttttgaggacccagatgtcaacaccaccaatctggaatttgaaat atgtggggccctcgtggaggtaaagtgcctgaatttcaggaaactacaagagatatatttcatcgagacaaagaaattct tactgattggaaagagcaatatatgtgtgaaggttggagaaaagagtctaacctgcaaaaaaatagacctaaccactata gttaaacctgaggctccttttgacctgagtgtcatctatcgggaaggagccaatgactttgtggtgacatttaatacatc acacttgcaaaagaagtatgtaaaagttttaatgcatgatgtagcttaccgccaggaaaaggatgaaaacaaatggacgc atgtgaatttatccagcacaaagctgacactcctgcagagaaagctccaaccggcagcaatgtatgagattaaagttcga tccatccctgatcactattttaaaggcttctggagtgaatggagtccaagttattacttcagaactccagagatcaataa tagctcaggggagatggatcct tcttactaaccatcagcattttgagttttttctctgtcgctctgttggtcatcttgg cctgtgtgttatggaaaaaaaggattaagcctatcgtatggcccagtctccccgatcataagaagactctggaacatctt tgtaagaaaccaagaaaaaatttaaatgtgagtttcaatcctgaaagtttcctggactgccagattcatagggtggatga cattcaagctagagatgaagtggaaggttttctgcaagatacgtttcctcagcaactagaagaatctgagaagcagaggc ttggaggggatgtgcagagccccaactgcccatctgaggatgtagtcgtcactccagaaagctttggaagagattcatcc ctcacatgcctggctgggaatgtcagtgcatgtgacgcccctattctctcctcttccaggtccctagactgcagggagag tggcaagaatgggcctcatgtgtaccaggacctcctgcttagccttgggactacaaacagcacgctgccccctccatttt ctctccaatctggaatcctgacattgaacccagttgctcagggtcagcccattcttacttccctgggatcaaatcaagaa gaagcatatgtcaccatgtccagcttctaccaaaaccagtgaagtgtaagaaacccagactgaacttaccgtgagcgaca aagatgatttaaaagggaagtctagagttcctagtctccctcacagcacagagaagacaaaattagcaaaaccccactac acagtctgcaagattctgaaacattgctttgaccactcttcctgagttcagtggcactcaacatgagtcaagagcatcct gcttctaccatgtggatttggtcacaaggtttaaggtgacccaatgattcagctattt (SEQ ID NO:12303) atacctaggcactaatttagttccatatgtactatgtgtacctgaaaagttgtgtggcaatcaaattttcacaaatagaa tcctgttttaaatacactaagaaagtacctactttatcctttaaacaagaggtcagcagactttttctacaaagggtcag atagtaaagattttacaccttttgtacaatacaatctctatctcatctacttagctctgccattgttgcataaaagcagc tgtagatgatacacaaatgggtgaggctgtattccaaatgaaacgttatttgcaaaaacaggtggtagattaaatttggt cccaaggcttacttgggaaaaaaaaagatcttttgaaaaagaaaaaataaatgaataatttttttaaaaaattgttccct aggtcatagtttgccagcccctgccctaaacaaataattcttgaatgcctactgtggtgtgtaagatatgagtaaatacc agggatacacagagaacaaaagagaaaaactgctattcttgtgaaacttggaagttggaggtaagctatttaaaataaac ccacaataaagtacttcacatagtgcagactgtttctttaaatcaaaactcactccaaacaaccaattgattcactttgt aagtttgaatttttgtcttcagattcttttaaagtgggcccttagtcaggagcggtggctcatgcctgtagtcctagcac tttgggaggctgaggcaggcagatcacttgaggtcaggagttcgagacaagcctggccaacatggcgaaaccccgtctcc actgaaaacacaaaaattaggctggcatagtggcatttgcctgtagtcctagctactcaggaggctgaggcaggagaatt gcttgaacctgggaggtgaaaattgcagtgagccgagatcatgctattgtactccagcctgggcaacaaagcaagactcg tc caaaaaaataaaaattaaaaaaataaagtagcctctagcctaagatagcttgagcctaggtgtgaatctactgcctt actctgatgtaagcacagtaagtgtgggggctgcagggaatatccaggaggaacaataatttcagaggctctgtctcttc atgtccttgacctctgcttacagcagcaatacttttactcagacttcctgtttctggaacttgccttcttttttgctgtg tttat cttcccttgtctgtggttagataagtataaagccctagatctaagcttctctgtcttcctccctccctcccttc ctcttactctcattcatttcatacacactggctcacacatctactctctctctctatctctctcagaatgacaattctag gtacaacttttggcatggttttttctttacttcaagtcgtttctggagaaagtggctatgctcaaaatggtgagtcattt ctaacttttcttatggattttggattatctgtagcatggtttcaggttattcagttccctaagagacctgagtcaggcac tgggtttgagtgcctctctctctatctctctcagaatgacaattctaggtacaacttttggcatggttttttctttactt caagtcgtttctggagaaagtggctatgctcaaaatggagacttggaagatgcagaactggatgactactcattctcatg ctatagccagttggaagtgaatggatcgcagcattcactgacctgtgcttttgaggacccagatgtcaacaccaccaatc tggaatttgaaatatgtggggccctcgtggaggtaaagtgcctgaatttcaggaaactacaagagatatatttcatcgag acaaagaaattcttactgattggaaagagcaatatatgtgtgaaggttggagaaaagagtctaacctgcaaaaaaataga cctaaccactatagttaaacctgaggctccttttgacctgagtgtcatctatcgggaaggagccaatgactttgtggtga catttaatacatcacacttgcaaaagaagtatgtaaaagttttaatgcatgatgtagcttaccgccaggaaaaggatgaa aacaaatggacgcatgtgaatttatccagcacaaagctgacactcctgcagagaaagctccaaccggcagcaatgtatga gattaaagttcgatccatccctgatcactattttaaaggcttctggagtgaatggagtccaagttattacttcagaactc cagagatcaataatagctcaggggagatggatcctatcttactaaccatcagcattttgagttttttctctgtcgctctg ttggtcatcttggcctgtgtgttatggaaaaaaaggattaagcc atcgtatggcccagtctccccgatcataagaagac tctggaacatctttgtaagaaaccaagaaaaaatttaaatgtgagtttcaatcctgaaagtttcctggactgccagattc atagggtggatgacattcaagctagagatgaagtggaaggttttctgcaagatacgtttcctcagcaactagaagaatct gagaagcagaggcttggaggggatgtgcagagccccaactgcccatctgaggatgtagtcgtcactccagaaagctttgg aagagattcatccctcacatgcctggctgggaatgtcagtgcatgtgacgcccctattctctcctcttccaggtccctag actgcagggagagtggcaagaatgggcctcatgtgtaccaggacctcctgcttagccttgggactacaaacagcacgctg ccccctccattttctctccaatctggaatcctgacattgaacccagttgctcagggtcagcccattcttacttccctggg atcaaatcaagaagaagcatatgtcaccatgtccagcttctaccaaaaccagtgaagtgtaagaaacccagactgaactt accgtgagcgacaaagatgatttaaaagggaagtctagagttcctagtctccctcacagcacagagaagacaaaattagc aaaaccccactacacagtctgcaagattctgaaacattgctttgaccactcttcctgagttcagtggcactcaacatgag tcaagagcatcctgcttctaccatgtggatttggtcacaaggtttaaggtgacccaatgattcagctattt (SEQ ID NO: 12304) ctcagcctcgctatggctcccagcagcccccggcccgcgctgcccgcactcctggtcctgctcggggctctgttcccagg acctggcaatgcccagacatctgtgtccccctcaaaagtcatcctgccccggggaggctccgtgctggtgacatgcagca cctcctgtgaccagcccaagttgttgggcatagagaccccgttgcctaaaaaggagttgctcctgcctgggaacaaccgg aaggtgtatgaactgagcaatgtgcaagaagatagccaaccaatgtgctattcaaactgccctgatgggcagtcaacagc taaaaccttcctcaccgtgtactggactccagaacgggtggaactggcacccctcccctcttggcagccagtgggcaaga accttaccctacgctgccaggtggagggtggggcaccccgggccaacctcaccgtggtgctgctccgtggggagaaggag ctgaaacgggagccagctgtgggggagcccgctgaggtcacgaccacggtgctggtgaggagagatcaccatggagccaa tttctcgtgccgcactgaactggacctgcggccccaagggctggagctgtttgagaacacctcggccccctaccagctcc agacctttgtcctgccagcgactcccccacaacttgtcagcccccgggtcctagaggtggacacgcaggggaccgtggtc tgttccctggacgggctgttcccagtctcggaggcccaggtccacctggcactgggggaccagaggttgaaccccacagt cacctatggcaacgactccttctcggccaaggcctcagtcagtgtgaccgcagaggacgagggcacccagcggctgacgt gtgcagtaatactggggaaccagagccaggagacactgcagacagtgaccatctacagctttccggcgcccaacgtgatt ctgacgaagccagaggtctcagaagggaccgaggtgacagtgaagtgtgaggcccaccctagagccaaggtgacgctgaa tggggttccagcccagccactgggcccgagggcccagctcctgctgaaggccaccccagaggacaacgggcgcagcttct cctgctctgcaaccctggaggtggccggccagcttatacacaagaaccagacccgggagcttcgtgtcctgtatggcccc cgactggacgagagggattgtccgggaaactggacgtggccagaaaattcccagcagactccaatgtgccaggcttgggg gaacccattgcccgagctcaagtgtctaaaggatggcactttcccactgcccatcggggaatcagtgactgtcactcgag atcttgagggcacctacctctgtcgggccaggagcactcaaggggaggtcacccgcgaggtgaccgtgaatgtgctctcc ccccggtatgagattgtcatcatcactgtggtagcagccgcagtcataatgggcactgcaggcctcagcacgtacctct taaccgccagcggaagatcaagaaatacagactacaacaggcccaaaaagggacccccatgaaaccgaacacacaagcca cgcctccctgaacctatcccgggacagggcctcttcctcggccttcccatattggtggcagtggtgccacactgaacaga gtggaagacatatgccatgcagctacacctaccggccctgggacgccggaggacagggcattgtcctcagtcagatacaa cagcatttggggccatggtacctgcacacctaaaacactaggccacgcatctgatctgtagtcacatgactaagccaaga ggaagg (SEQ ID NO: 12305) ctaaagatctccctccaggcagcccttggctggtccctgcgagcccgtggagactgccagagatgtcctctttcggttac aggaccctgactgtggccctcttcaccctgatctgctgtccaggatcggatgagaaggtattcgaggtacacgtgaggcc aaagaagctggcggttgagcccaaagggtccctcgaggtcaactgcagcaccacctgtaaccagcctgaagtgggtggtc tggagacctctctaaataagattctgctggacgaacaggctcagtggaaacattacttggtctcaaacatctcccatgac acggtcctccaatgccacttcacctgctccgggaagcaggagtcaatgaattccaacgtcagcgtgtaccagcctccaag gcaggtcatcctgacactgcaacccactttggtggctgtgggcaagtccttcaccattgagtgcagggtgcccaccgtgg agcccctggacagcctcaccctcttcctgttccgtggcaatgagactctgcactatgagaccttcgggaaggcagcccct gctccgcaggaggccacagccacattcaacagcacggctgacagagaggatggccaccgcaacttctcctgcctggctgt gctggacttgatgtctcgcggtggcaacatctttcacaaacactcagccccgaagatgttggagatctatgagcctgtgt cggacagccagatggtcatcatagtcacggtggtgtcggtgttgctgtccctgttcgtgacatctgtcctgctctgcttc atcttcggccagcacttgcgccagcagcggatgggcacctacggggtgcgagcggcttggaggaggctgccccaggcctt ccggccatagcaaccatgagtggcatggccaccaccacggtggtcactggaactcagtgtgactcctcagggttgaggtc cagccctggctgaaggactgtgacaggcagcagagacttgggacattgccttttctagcccgaatacaaacacctggact t (SEQ ID NO:12306) ctcagcctcgctatggctcccagcagcccccggcccgcgctgcccgcactcctggtcctgctcggggctctgttcccagg acctggcaatgcccagacatctgtgtccccctcaaaagtcatcctgccccggggaggctccgtgctggtgacatgcagca cctcctgtgaccagcccaagttgttgggcatagagaccccgttgcctaaaaaggagttgctcctgcctgggaacaaccgg aaggtgtatgaactgagcaatgtgcaagaagatagccaaccaatgtgctattcaaactgccctgatgggcagtcaacagc taaaaccttcctcaccgtgtactggactccagaacgggtggaactggcacccctcccctcttggcagccagtgggcaaga accttaccctacgctgccaggtggagggtggggcaccccgggccaacctcaccgtggtgctgctccgtggggagaaggag ctgaaacgggagccagctgtgggggagcccgctgaggtcacgaccacggtgctggtgaggagagatcaccatggagccaa tttctcgtgccgcactgaactggacctgcggccccaagggctggagctgtttgagaacacctcggccccctaccagctcc agacctttgtcctgccagcgactcccccacaacttgtcagcccccgggtcctagaggtggacacgcaggggaccgtggtc tgttccctggacgggctgttcccagtctcggaggcccaggtccacctggcactgggggaccagaggttgaaccccacagt cacctatggcaacgactccttctcggccaaggcctcagtcagtgtgaccgcagaggacgagggcacccagcggctgacgt gtgcagtaatactggggaaccagagccaggagacactgcagacagtgaccatctacagctttccggcgcccaacgtgatt ctgacgaagccagaggtctcagaagggaccgaggtgacagtgaagtgtgaggcccaccctagagccaaggtgacgctgaa tggggttccagcccagccactgggcccgagggcccagctcctgctgaaggccaccccagaggacaacgggcgcagcttct cctgctctgcaaccctggaggtggccggccagcttatacacaagaaccagacccgggagcttcgtgtcctgtatggcccc cgactggacgagagggattgtccgggaaactggacgtggccagaaaattcccagcagactccaatgtgccaggcttgggg gaacccattgcccgagctcaagtgtctaaaggatggcactttcccactgcccatcggggaatcagtgactgtcactcgag atcttgagggcacctacctctgtcgggccaggagcactcaaggggaggtcacccgcgaggtgaccgtgaatgtgctctcc ccccggtatgagattgtcatcatcactgtggtagcagccgcagtcataatgggcactgcaggcctcagcacgtacctcta taaccgccagcggaagatcaagaaatacagactacaacaggcccaaaaagggacccccatgaaaccgaacacacaagcca cgcctccctgaacctatcccgggacagggcctcttcctcggccttcccatattggtggcagtggtgccacactgaacaga gtggaagacatatgccatgcagctacacctaccggccctgggacgccggaggacagggcattgtcctcagtcagatacaa cagcatttggggccatggtacctgcacacctaaaacactaggccacgcatctgatctgtagtcacatgactaagccaaga ggaaggctaaagatctccctccaggcagcccttggctggtccctgcgagcccgtggagactgccagagatgtcctctttc ggttacaggaccctgactgtggccctcttcaccctgatctgctgtccaggatcggatgagaaggtattcgaggtacacgt gaggccaaagaagctggcggttgagcccaaagggtccctcgaggtcaactgcagcaccacctgtaaccagcctgaagtgg gtggtctggagacctctctaaataagattctgctggacgaacaggctcagtggaaacattacttggtctcaaacatctcc catgacacggtcctccaatgccacttcacctgctccgggaagcaggagtcaatgaattccaacgtcagcgtgtaccagcc tccaaggcaggtcatcctgacactgcaacccactttggtggctgtgggcaagtccttcaccattgagtgcagggtgccca ccgtggagcccctggacagcctcaccctcttcctgttccgtggcaatgagactctgcactatgagaccttcgggaaggca gcccctgctccgcaggaggccacagccacattcaacagcacggctgacagagaggatggccaccgcaacttctcctgcct ggctgtgctggacttgatgtctcgcggtggcaacatctttcacaaacactcagccccgaagatgttggagatctatgagc ctgtgtcggacagccagatggtcatcatagtcacggtggtgtcggtgttgctgtccctgttcgtgacatctgtcctgctc tgcttcatcttcggccagcacttgcgccagcagcggatgggcacctacggggtgcgagcggcttggaggaggctgcccca ggccttccggccatagcaaccatgagtggcatggccaccaccacggtggtcactggaactcagtgtgactcctcagggtt gaggtccagccctggctgaaggactgtgacaggcagcagagacttgggacattgccttttctagcccgaatacaaacacc tggactt (SEQ ID NO: 12307) aatggccaccatggtaccatccgtgttgtggcccagggcctgctggactctgctggtctgctgtctgctgaccccaggtg tccaggggcaggagttccttttgcgggtggagccccagaaccctgtgctctctgctggagggtccctgtttgtgaactgc agtactgattgtcccagctttgagaaaatcgccttggagacgtccctatcaaaggagctggtggccagtggcatgggctg ggcagccttcaatctcagcaacgtgactggcaacagtcggatcctctgctcagtgtactgcaatggctcccagataacag gctcctctaacatcaccgtgtacgggctcccggagcgtgtggagctggcacccctgcctccttggcagccggtgggccag aacttcaccctgcgctgccaagtggagggtgggtcgccccggaccagcctcacggtggtgctgcttcgctgggaggagga gctgagccggcagcccgcagtggaggagccagcggaggtcactgccactgtgctggccagcagagacgaccacggagccc ctttctcatgccgcacagaactggacatgcagccccaggggctgggactgttcgtgaacacctcagccccccgccagctc cgaacctttgtcctgcccgtgacccccccgcgcctcgtggccccccggttcttggaggtggaaacgtcgtggccggtgga ctgcaccctagacgggctttttccagcctcagaggcccaggtctacctggcgctgggggaccagatgctgaatgcgacag tcatgaaccacggggacacgctaacggccacagccacagccacggcgcgcgcggatcaggagggtgcccgggagatcgtc tgcaacgtgaccctagggggcgagagacgggaggcccgggagaacttgacggtctttagcttcctaggacccattgtgaa cctcagcgagcccaccgcccatgaggggtccacagtgaccgtgagttgcatggctggggctcgagtccaggtcacgctgg acggagttccggccgcggccccggggcagccagctcaacttcagctaaatgctaccgagagtgacgacggacgcagcttc ttctgcagtgccactctcgaggtggacggcgagttcttgcacaggaacagtagcgtccagctgcgagtcctgtatggtcc caaaattgaccgagccacatgcccccagcacttgaaatggaaagataaaacgagacacgtgctgcagtgccaagccaggg gcaacccgtaccccgagctgcggtgtttgaaggaaggctccagccgggaggtgccggtggggatcccgttcttcgtcaac gtaacacataatggtacttatcagtgccaagcgtccagctcacgaggcaaatacaccctggtcgtggtgatggacattga ggctgggagctcccactttgtccccgtcttcgtggcggtgttactgaccctgggcgtggtgactatcgtactggccttaa tgtacgtcttcagggagcaccaacggagcggcagttaccatgttagggaggagagcacctatctgcccctcacgtctatg cagccgacagaagcaatgggggaagaaccgtccagagctgagtgacgctgggatccgggatcaaagttggcgggggcttg gctgtgccctcagattccgcaccaataaagccttcaaaccctaaaaaaaaaaaaaaaaa (SEQ ID NO:12308) gcacggaggggcagagaccccggagccccagccccaccatgaccctcggccgccgactcgcgtgtcttttcctcgcctgt gtcctgccggccttgctgctggggggcaccgcgctggcctcggagattgtggggggccggcgagcgcggccccacgcgtg gcccttcatggtgtccctgcagctgcgcggaggccacttctgcggcgccaccctgattgcgcccaacttcgtcatgtcgg ccgcgcactgcgtggcgaatgtaaacgtccgcgcggtgcgggtggtcctgggagcccataacctctcgcggcgggagccc acccggcaggtgttcgccgtgcagcgcatcttcgaaaacggctacgaccccgtaaacttgctcaacgacatcgtgattct ccagctcaacgggtcggccaccatcaacgccaacgtgcaggtggcccagctgccggctcagggacgccgcctgggcaacg gggtgcagtgcctggccatgggctggggccttctgggcaggaaccgtgggatcgccagcgtcctgcaggagctcaacgtg acggtggtgacgtccctctgccgtcgcagcaacgtctgcactctcgtgaggggccggcaggccggcgtctgtttcgggga ctccggcagccccttggtctgcaacgggctaatccacggaattgcctccttcgtccggggaggctgcgcctcagggctct accccgatgcctttgccccggtggcacagtttgtaaactggatcgactctatcatccaacgctccgaggacaacccctgt ccccacccccgggacccggacccggccagcaggacccactgagaagggctgcccgggtcacctcagctgcccacacccac actctccagcatctggcacaataaacattctctgttttgt (SEQ ID NO:12309) ttgtcagagccccagctggtgtccagggactgaccgtgagcctgggtgaaagtgagttccccgttggaggcaccagacga ggagaggatggaaggcctggcccccaagaatgagccctgaggttcaggagcggctggagtgagccgcccccagatctccg tccagctgcgggtcccagaggcctgggttacactcggagctcctgggggaggcccttgacgtgctcagttcccaaacagg aaccctgggaaggaccagagaagtgcctattgcgcagtgagtgcccgacacagctgcatgtggccggtatcacagggccc tgggtaaactgaggcaggcgacacagctgcatgtggccggtatcacagggccctgggtaaactgaggcaggcgacacagc tgcatgtggccggtatcacagggccctgggtaaactgaggcaggcgacacagctgcatgtggccggtatcacagggccct gggtaaactgaggcaggcgacacagctgcatgtggccggt tcacggggccctggataaacagaggcaggcgaggccacc cccatcaagtccctcaggtctaggtttggccaggtttggaaaaacacagcaacgctcggtaaatctgaatttcgggtaag tatatcctgggcctcatttggaagagacttagattaaaaaaaaaacgtcgagaccagcccggccaacacgtgaaaccccg tctctactaaaaatacaaaaaattagccaggcgcagtgctcacgcctgtgatcccagcactctgggaggtgaggcaggcg gatcacccgaggtcagctgttcaagaccagcctggccgagtgggcgaaacactgtctctactacaaatacaaaaattagc cgggagtggaggcaggtgcctgtaatctcagctattcaggaggctgaggcaggagaatcacttgaacctgggaggcggag gttgccgtgagccgggatcacgccaccgcactccagcctgggcgatagagcaagactctgtctccaaaaaaataaattaa aaaacccacattgattatctgacatttgaatgcgattgtgcatcctgaattttgtctggaggccccacccgagccaatcc agcgtcttgtcccccttctcccccttttcatcaacgcctgtgccaggggagaggaagtggagggcgctggccggccgtgg ggcaatgcaacggcctcccagcacagggctataagaggagccgggcgggcacggaggggcagagaccccggagccccagc cccaccatgaccctcggccgccgactcgcgtgtcttttcctcgcctgtgtcctgccggccttgctgctggggggtgagtt tttgagtccaacctcccgctgctccctctgtcccgggttctgttcccacctctccatagagggccccaccagtgtgggtc cctcatcctcacaggggaggtgccagctgggacaaggagaccagaagagactgaggttctgagcggtgaagccaccacca ggagcccagagttggggtttgaaaaccggggagggggggggtggcaggtcgccctctgggttcaagtccaggtctgtctg tgccttggaggggcaccgtggggaggtccctttgcctctccgtgcctcagtttcctcatctgaacaacaggggtgcgaac ggccccgatcccgtgggttcccggtgggggatccagaggccccgtggccgggaggggacaggctccttggcaggcactca gcacccgcacccggtgtgtccccaggcaccgcgctggcctcggagattgtggggggccggcgagcgcggccccacgcgtg gcccttcatggtgtccctgcagctgcgcggaggccacttctgcggcgccaccctgattgcgcccaacttcgtcatgtcgg ccgcgcactgcgtggcgaatgtgtgagtagccgggagtgtgcgcgcccggctcggaccccgcgtcccggtctgtgaggtg ggtggggggaggccggggccggggctgctggcgggggggggtccgtccagggcccgcggggcccctcgagcaccttcgcc ctcaggcccgtcgccggatggggacgacaaggcgcggctgagccccgacccccggggccgcccctgagccccgcctctcc ctcttttggcagaaacgtccgcgcggtgcgggtggtcctgggagcccataacctctcgcggcgggagcccacccggcagg tgttcgccgtgcagcgcatcttcgaaaacggctacgaccccgtaaacttgctcaacgacatcgtgattctccaggtgccg ccgggcgggcgggggcgaggggcggaggccagaggcctggggagggtggaggcctggggagggtggaggctgcgacggag gggcgcgtcggggccgctcgtggggacctggggtggcatcgtgggctgggtggtcccctctccgcgcctcggtctgcacc tctgtgaaacgggaaaatacccgccatgggccgttgaggggttaaatgagatcctgcagggaggccccgatctgctgtca atcaacaaacttactgagaagggaggccccgatctgttgtcaatcaacaaacttactgagaagggaggccccgatctgtt gtcaatcaacaaacttactgagaagggaggccccgatctgctgtcaatcaacaaacttactgagaagggaggccccgatg ttgtcaatcaacaaacttactgagaagggaggccccgatctgctgtcaatcaaccaaacttactgagaagggaggccccg atctgctgtcaatca caaacttactgagaagggaggccccgatctgctgtcaatcaacaaacttactgagaagggaggc ccccgatctgttgtcaatcaacaaacttactgagaagggaggccccgatctgctgtcaatcaacaaacttactgagattc tgtgtgtctctccattcaccagtcctgtggcccagggcaggggccgcctctgtctttgggaaaaggggcaaaagtcccca cctttccacccctgtccgcggcttgcagttctggttatttcctgggcgccgggccccgtggctcaggcctgtcatcccag cactttgggaggctgaggcgggtggatcacgaggtcaggtgttcgagaccagcctgagcaacatagtgaaaccccgtctc tactaaaatacacaaaaaaaaaattagccgagtgtggttgtgggtgcctgtaatgccaactactcaggaggctgaggaag gagaatcgcttgaaccccggaggcggagattgcagtgagctgagatcacaccactgcactccagcctgggtctcaaaaaa aaaaaaaaagattcctccctgggaagggttagagggagagtttccttgtcactaagttttctcatagctctcacccagtg cagtggcgcgatcgcagctcactacacctccatctcctgggctcaagccaccctctcagcttggaatggggggtagctgg aaccacaggtgccaccacgtggtccaccacgtctggctaatatatatatatacacacacacatacatatattataaataa taaatatatattttatttaaataaaatatataatatttataattattttataattataataatatttatataattataaa tatcatttataattataatatttattattttataaaataataaatataaaatatataaaaatatttttataaataataaa atatatatatacacacatatatatatattttttgagacaagtctcgctctgtcgcccaggctggagcgcagtgcacaatc tcactcactgcacctccgcctcccaggttcaagcgattctcctgcctcagcctcccaggtagctgggactacaggcgccc gccaccacgcctggctaatttttggtattgttagtagagacggggtttaaccatgttagccaggatggtcttgatctcct gaccttttgattggcccacctcagcctcccaaaatgctgggattataggcgtgagcaccgcacctggcaattttttttta ttatttttgtagacatggggctttgccacattgcccaggctggtcttgaatgcctggcctggcctaagtgatcctcctgc ctcgccctcccaaagtgctgggcttacaagcatgagccaccgcgcccggctgtagtttttttgttaactgagcacctact gcttcctgcactcaagccacatccagggacaacctccaacgccctgagccttggtgacggctcccactctacagatgggg aaaccgaggcttgccttggggagcagagtgtggggtgggtatcctgccctgcaggatcccagaaccacagtggaacctga gatggggaaactgaggcccggagaggggagggtcatcatcactgccccgtgtgacgcgctgacgatctgtccccaccgcc acagctcaacgggtcggccaccatcaacgccaacgtgcaggtggcccagctgccggctcagggacgccgcctgggcaacg gggtgcagtgcctggccatgggctggggccttctgggcaggaaccgtgggatcgccagcgtcctgcaggagctcaacgtg acggtggtgacgtccctctgccgtcgcagcaacgtctgcactctcgtgaggggccggcaggccggcgtctgtttcgtacg tgccctgggtgtccctctgctccccacccgctcccagcccggtactgcagcaacaggcaccgtggctagaccctaggatg ggacttcccaaccctgacacgtcggcgggcaggtgggcagggcctcgcagtccagcttccccaccttgtctgcctccaca gggggactccggcagccccttggtctgcaacgggctaatccacggaattgcctccttcgtccggggaggctgcgcctcag ggctctaccccgatgcctttgccccggtggcacagtttgtaaactggatcgactctatcatccaacgctccgaggacaac ccctgtccccacccccgggacccggacccggccagcaggacccactgagaagggctgcccgggtcacctcagctgcccac acccacactctccagcatctggcacaataaacattctctgttttgtagaatgtgtttgatgctccttggctgtgtgattg ggtgttgaaaatggtcagtaggtcgggcgtggtggctcacacctgtaatcccagcactttgggaggttgaggcaggcgga tcacttgagctc (SEQ ID NO:12310) gcacggaggggcagagaccccggagccccagccccaccatgaccctcggccgccgactcgcgtgtcttttcctcgcctgt gtcctgccggccttgctgctggggggcaccgcgctggcctcggagattgtggggggccggcgagcgcggccccacgcgtg gcccttcatggtgtccctgcagctgcgcggaggccacttctgcggcgccaccctgattgcgcccaacttcgtcatgtcgg ccgcgcactgcgtggcgaatgtaaacgtccgcgcggtgcgggtggtcctgggagcccataacctctcgcggcgggagccc acccggcaggtgttcgccgtgcagcgcatcttcgaaaacggctacgaccccgtaaacttgctcaacgacatcgtgattct ccagctcaacgggtcggccaccatcaacgccaacgtgcaggtggcccagctgccggctcagggacgccgcctgggcaacg gggtgcagtgcctggccatgggctggggccttctgggcaggaaccgtgggatcgccagcgtcctgcaggagctcaacgtg acggtggtgacgtccctctgccgtcgcagcaacgtctgcactctcgtgaggggccggcaggccggcgtctgtttcgggga ctccggcagccccttggtctgcaacgggctaatccacggaattgcctccttcgtccggggaggctgcgcctcagggctct accccgatgcctttgccccggtggcacagtttgtaaactggatcgactctatcatccaacgctccgaggacaacccctgt ccccacccccgggacccggacccggccagcaggacccactgagaagggctgcccgggtcacctcagctgcccacacccac actctccagcatctggcacaataaacattctctgttttgtttgtcagagccccagctggtgtccagggactgaccgtgag cctgggtgaaagtgagttccccgttggaggcaccagacgaggagaggatggaaggcctggcccccaagaatgagccctga ggttcaggagcggctggagtgagccgcccccagatctccgtccagctgcgggtcccagaggcctgggttacactcggagc tcctgggggaggcccttgacgtgctcagttcccaaacaggaaccctgggaaggaccagagaagtgcctattgcgcagtga gtgcccgacacagctgcatgtggccggtatcacagggccctgggtaaactgaggcaggcgacacagctgcatgtggccgg tatcacagggccctgggtaaactgaggcaggcgacacagctgcatgtggccggtatcacagggccctgggtaaactgagg caggcgacacagctgcatgtggccggtatcacagggccctgggtaaactgaggcaggcgacacagctgcatgtggccggt atcacggggccctggataaacagaggcaggcgaggccacccccatcaagtccctcaggtctaggtttggccaggtttgga aaaacacagcaacgctcggtaaatctgaatttcgggtaagtatatcctgggcctcatttggaagagacttagattaaaaa aaaaacgtcgagaccagcccggccaacacgtgaaaccccgtctctactaaaaatacaaaaaattagccaggcgcagtgct cacgcctgtgatcccagcactctgggaggtgaggcaggcggatcacccgaggtcagctgttcaagaccagcctggccgag tgggcgaaacactgtctctactacaaatacaaaaattagccgggagtggaggcaggtgcctgtaatctcagctattcagg aggctgaggcaggagaatcacttgaacctgggaggcggaggttgccgtgagccgggatcacgccaccgcactccagcctg ggcgatagagcaagactctgtctccaaaaaaataaattaaaaaacccacattgattatctgacatttgaatgcgattgtg catcctgaattttgtctggaggccccacccgagccaatccagcgtcttgtcccccttctcccccttttcatcaacgcctg tgccaggggagaggaagtggagggcgctggccggccgtggggcaatgcaacggcctcccagcacagggctataagaggag ccgggcgggcacggaggggcagagaccccggagccccagccccaccatgaccctcggccgccgactcgcgtgtcttttcc tcgcctgtgtcctgccggccttgctgctggggggtgagtttttgagtccaacctcccgctgctccctctgtcccgggttc tgttcccacctctccatagagggccccaccagtgtgggtccctcatcctcacaggggaggtgccagctgggacaaggaga ccagaagagactgaggttctgagcggtgaagccaccaccaggagcccagagttggggtttgaaaaccggggagggggggg gtggcaggtcgccctctgggttcaagtccaggtctgtctgtgccttggaggggcaccgtggggaggtccctttgcctctc cgtgcctcagtttcctcatctgaacaacaggggtgcgaacggccccgatcccgtgggttcccggtgggggatccagaggc cccgtggccgggaggggacaggctccttggcaggcactcagcacccgcacccggtgtgtccccaggcaccgcgctggcct cggagattgtggggggccggcgagcgcggccccacgcgtggcccttcatggtgtccctgcagctgcgcggaggccacttc tgcggcgccaccctgattgcgcccaacttcgtcatgtcggccgcgcactgcgtggcgaatgtgtgagtagccgggagtgt gcgcgcccggctcggaccccgcgtcccggtctgtgaggtgggtggggggaggccggggccggggctgctggcgggggggg gtccgtccagggcccgcggggcccctcgagcaccttcgccctcaggcccgtcgccggatggggacgacaaggcgcggctg agccccgacccccggggccgcccctgagccccgcctctccctcttttggcagaaacgtccgcgcggtgcgggtggtcctg ggagcccataacctctcgcggcgggagcccacccggcaggtgttcgccgtgcagcgcatcttcgaaaacggctacgaccc cgtaaacttgctcaacgacatcgtgattctccaggtgccgccgggcgggcgggggcgaggggcggaggccagaggcctgg ggagggtggaggcctggggagggtggaggctgcgacggaggggcgcgtcggggccgctcgtggggacctggggtggcatc gtgggctgggtggtcccctctccgcgcctcggtctgcacctctgtgaaacgggaaaatacccgccatgggccgttgaggg gttaaatgagatcctgcagggaggccccgatctgctgtcaatcaacaaacttactgagaagggaggccccgatctgttgt caatcaacaaacttactgagaagggaggccccgatctgttgtcaatcaacaaacttactgagaagggaggccccgatctg ctgtcaatcaacaaacttactgagaagggaggccccgatgttgtcaatcaacaaacttactgagaagggaggccccgatc tgctgtcaatcaaccaaacttactgagaagggaggccccgatctgctgtcaatcatcaaacttactgagaagggaggccc cgatctgctgtcaatcaacaaacttactgagaagggaggcccccgatctgttgtcaatcaacaaacttactgagaaggga ggccccgatctgctgtcaatcaacaaacttactgagattctgtgtgtctctccattcaccagtcctgtggcccagggcag gggccgcctctgtctttgggaaaaggggcaaaagtccccacctttccacccctgtccgcggcttgcagttctggttattt cctgggcgccgggccccgtggctcaggcctgtcatcccagcactttgggaggctgaggcgggtggatcacgaggtcaggt gttcgagaccagcctgagcaacatagtgaaaccccgtctctactaaaatacacaaaaaaaaaattagccgagtgtggttg tgggtgcctgtaatgccaactactcaggaggctgaggaaggagaatcgcttgaaccccggaggcggagattgcagtgagc tgagatcacaccactgcactccagcctgggtctcaaaaaaaaaaaaaaagattcctccctgggaagggttagagggagag tttccttgtcactaagttttctcatagctctcacccagtgcagtggcgcgatcgcagctcactacacctccatctcctgg gctcaagccaccctctcagcttggaatggggggtagctggaaccacaggtgccaccacgtggtccaccacgtctggctaa ta atatatatacacacacacatacatatattataaataataaatatatattttatttaaataaaatatataatatttat aattattttataattataataatatttatataattataaatatcatttataattataatatttattattttataaaataa taaatataaaatatataaaaatatttttataaataataaaatatatatatacacacatata atatattttttgagacaa gtctcgctctgtcgcccaggctggagcgcagtgcacaatctcactcactgcacctccgcctcccaggttcaagcgattct cctgcctcagcctcccaggtagctgggactacaggcgcccgccaccacgcctggctaatttttggtattgttagtagaga cggggtttaaccatgttagccaggatggtcttgatctcctgaccttttgattggcccacctcagcctcccaaaatgctgg gattataggcgtgagcaccgcacctggcaatttttttttattatttttgtagacatggggctttgccacattgcccaggc tggtcttgaatgcctggcctggcctaagtgatcctcctgcctcgccctcccaaagtgctgggcttacaagcatgagccac cgcgcccggctgtagtttttttgttaactgagcacctactgcttcctgcactcaagccacatccagggacaacctccaac gccctgagccttggtgacggctcccactctacagatggggaaaccgaggcttgccttggggagcagagtgtggggtgggt atcctgccctgcaggatcccagaaccacagtggaacctgagatggggaaactgaggcccggagaggggagggtca catc actgccccgtgtgacgcgctgacgatctgtccccaccgccacagctcaacgggtcggccaccatcaacgccaacgtgcag gtggcccagctgccggctcagggacgccgcctgggcaacggggtgcagtgcctggccatgggctggggccttctgggcag gaaccgtgggatcgccagcgtcctgcaggagctcaacgtgacggtggtgacgtccctctgccgtcgcagcaacgtctgca ctctcgtgaggggccggcaggccggcgtctgtttcgtacgtgccctgggtgtccctctgctccccacccgctcccagccc ggtactgcagcaacaggcaccgtggctagaccctaggatgggacttcccaaccctgacacgtcggcgggcaggtgggcag ggcctcgcagtccagcttccccaccttgtctgcctccacagggggactccggcagccccttggtctgcaacgggctaatc cacggaattgcctccttcgtccggggaggctgcgcctcagggctctaccccgatgcctttgccccggtggcacagtttgt aaactggatcgactctatcatccaacgctccgaggacaacccctgtccccacccccgggacccggacccggccagcagga cccactgagaagggctgcccgggtcacctcagctgcccacacccacactctccagcatctggcacaataaacattctctg ttttgtagaatgtgtttgatgctccttggctgtgtgattgggtgttgaaaatggtcagtaggtcgggcgtggtggctcac acctgtaatcccagcactttgggaggttgaggcaggcggatcacttgagctc (SEQ ID NO: 12311) ctattgcagtatctttcagcttccagtcttatctgaagaccccggcaccaaagtgaccaggaggcagagaagaacttcag aggagtctcgtcttgggctgcccgtgggtgagtgggagggtccgggactgcagaccggtggcgatggccactctcccagc agcagaaacctggatagacgggggtggaggcgtgggtgcagacgccgtgaacctgaccgcctcgctagctgccggggcgg ccacgggggcagttgagactgggtggctgcaactgctggaccaagctggcaacctctcctcctccccttccgcgctggga ctgcctgtggcttcccccgcgccctcccagccctgggccaacctcaccaaccagttcgtgcagccgtcctggcgcatcgc gctctggtccctggcgtatggtgtggtggtggcagtggcagttttgggaaatctcatcgtcatctggatcatcctggccc acaagcgcatgaggactgtcaccaactacttccttgtgaacctggctttctccgacgcctccatggccgccttcaacacg ttggtcaatttcatctacgcgcttcatagcgagtggtactttggcgccaactactgccgcttccagaacttctttcctat cacagctgtgttcgccagcatctactccatgacggccattgcggtggacaggtatatggctattattgatcccttgaaac ccagactgtctgctacagcaaccaagattgtcattggaagtatttggattctagcatttctacttgccttccctcagtgt ctttattccaaaaccaaagtcatgccaggccgtactctctgctttgtgcaatggccagaaggtcccaaacaacatttcac ttaccatattatcgtcattatactggtgtactgtttcccattgctcatcatgggtattacatacaccattgttggaatta ctctctggggaggagaaatcccaggagatacctgtgacaagtatcatgagcagctaaaggccaaaagaaaggttgtcaaa atgatgattattgttgtcatgacatttgctatctgctggctgccctatcatatttacttcattctcactgcaatctatca acaactaaatagatggaaatacatccagcaggtctacctggctagcttttggctggcaatgagctcaaccatgtacaatc ccatcatctactgctgtctgaataaaagatttcgagctggcttcaagagagcatttcgctggtgtcctttca caaagtt tccagctatgatgagctagagctcaagaccaccaggtttcatccaaaccggcaaagcagtatgtacaccgtgaccagaat ggagtccatgacagtcgtgtttgaccccaacgatgcagacaccaccaggtccagtcggaagaaaagagcaacgccaagag acccaagtttcaatggctgctctcgcaggaattccaaatctgcctccgccacttcaagtttcataagctcaccctatacc tctgtggatgaatattcttaattccatttcctgaggtaaaagattagtgtgagaccatcatggtgccagtctaggacccc attctcctatttatcagtcctgtcctatataccctctagaaacagaaagcaatttttaggcagctatggtcaaattgaga aaggtagtgtataaatgtgacaaagacactaataacatgttagcctccacccaaaataaaatgggctttaaattt (SEQ ID NO:12312) ctgcagaccggtggcgatggccatcctcccagcagcagaaacctggatagacgggggtggaggcgtgggtgcagacgccg tgaacctgaccgcctcgctagctgccggggcggccacgggggcagttgagactgggtggctgcaactgctggaccaagct ggcaacctctcctcctccccttccgcgctgggactgcctgtgcgttcccccgcgccctcccagccctgggccaacctcac caaccagttcgtgcagccgtcctggcgtatcgcgctctggtccctggcgtatggtgtggtggtggcagtggcagttttgg gaaatctcatcgtcatctggatca cctggcccacaagcgcatgaggactgtcaccaactacttccttgtgaacctggct ttctccgacgcctccatggccgccttcaacacgttggtcaatttcatctacgcgcttcatagcgagtggtactttggcgc caactactgccgcttccagaacttc ttcctatcacagctgtgttcgccagcatctactccatgacggccattgcggtgg acaggtgaggagaggacagacagagaggaaagagggagaa (SEQ ID NO: 12313) ggta atggctattattgatcccttgaaacccagactgtctgctacagcaaccaagattgtcattggaagtatttggatt ctagcatttctacttgccttccctcagtgtctttattccaaaaccaaagtcatgccaggccgtactctctgctttgtgca atggccagaaggtcccaaacaacatttcacgtaagttaattctctattatggttttcaattcagttt (SEQ ID NO: 12314) catgtgtttttcttatttttcatagttaccatattatcgtcattatactggtgtactgtttcccattgctcatcatgggt attacatacaccattgttggaattactctctggggaggagaaatcccaggagatacctgtgacaagtatcatgagcagct aaaggccaaaagaaaggtactggtccatgttgtttacctag (SEQ ID NO: 12315) caaatgactttttctttataggttgtcaaaatgatgattattgttgtcatgacatttgctatctgctggctgccctatca tatttacttcattctcactgcaatctatcaacaactaaatagatggaaatacatccagcaggtctacctggctagctttt ggctggcaatgagctcaaccatgtacaatcccatcatctactgctgtctgaataaaaggtaaaaacaaaactacgaaatg caagttgcttgtcac (SEQ ID NO: 12316) aaaataacttttctttctgtggcctgcttttcctcagatttcgagctggcttcaagagagcatttcgctggtgtcctttc a caaagtttccagctatgatgagctagagctcaagaccaccaggtt catccaaaccggcaaagcagtatgtacaccgt gaccagaatggagtccatgacagtcgtgtttgaccccaacgatgcagacaccaccaggtccagtcggaagaaaagagcaa cgccaagagacccaagtttcaatggctgctctcgcaggaattccaaatctgcctccgccacttcaagtttcataagctca ccctatacctctgtggatgaatattcttaattccatttcctgaggtaaaagattagtgtgagaccatcatggtgccagtc taggaccccattctcctatttatcagtcctgtcctatataccctctaga (SEQ ID NO: 12317) ctgcagaccggtggcgatggccatcctcccagcagcagaaacctggatagacgggggtggaggcgtgggtgcagacgccg tgaacctgaccgcctcgctagctgccggggcggccacgggggcagttgagactgggtggctgcaactgctggaccaagct ggcaacctctcctcctccccttccgcgctgggactgcctgtgcgttcccccgcgccctcccagccctgggccaacctcac caaccagttcgtgcagccgtcctggcgtatcgcgctctggtccctggcgtatggtgtggtggtggcagtggcagttttgg gaaatctcatcgtcatctggatcatcctggcccacaagcgcatgaggactgtcaccaactacttccttgtgaacctggct ttctccgacgcctccatggccgccttcaacacgttggtcaatttcatctacgcgcttcatagcgagtggtactttggcgc caactactgccgcttccagaacttctttcctatcacagctgtgttcgccagcatctactccatgacggccattgcggtgg acaggtgaggagaggacagacagagaggaaagagggagaactattgcagtatctttcagcttccagtcttatctgaagac cccggcaccaaagtgaccaggaggcagagaagaacttcagaggagtctcgtcttgggctgcccgtgggtgagtgggaggg tccgggactgcagaccggtggcgatggccactctcccagcagcagaaacctggatagacgggggtggaggcgtgggtgca gacgccgtgaacctgaccgcctcgctagctgccggggcggccacgggggcagttgagactgggtggctgcaactgctgga ccaagctggcaacctctcctcctccccttccgcgctgggactgcctgtggcttcccccgcgccctcccagccctgggcca acctcaccaaccagttcgtgcagccgtcctggcgcatcgcgctctggtccctggcgtatggtgtggtggtggcagtggca gttttgggaaatctcatcgtcatctggatcatcctggcccacaagcgcatgaggactgtcaccaactacttccttgtgaa cctggctttctccgacgcctccatggccgccttcaacacgttggtcaatttcatctacgcgcttcatagcgagtggtact ttggcgccaactactgccgcttccagaacttctttcctatcacagctgtgttcgccagcatctactccatgacggccatt gcggtggacaggtatatggctattattgatcccttgaaacccagactgtctgctacagcaaccaagattgtcattggaag tatttggattctagcatttctacttgccttccctcagtgtctttattccaaaaccaaagtcatgccaggccgtactctct gctttgtgcaatggccagaaggtcccaaacaacatttcacttaccatattatcgtcattatactggtgtactgtttccca ttgctcatcatgggt ttacatacaccattgttggaattactctctggggaggagaaatcccaggagatacctgtgacaa gtatcatgagcagctaaaggccaaaagaaaggttgtcaaaatgatgattattgttgtcatgacatttgctatctgctggc tgccctatcatatttacttcattctcactgcaatctatcaacaactaaatagatggaaatacatccagcaggtctacctg gctagcttttggctggcaatgagctcaaccatgtacaatcccatcatctactgctgtctgaataaaagatttcgagctgg cttcaagagagcatttcgctggtgtcctttcatcaaagtttccagctatgatgagctagagctcaagaccaccaggtttc a ccaaaccggcaaagcagtatgtacaccgtgaccagaatggagtccatgacagtcgtgtttgaccccaacgatgcagac accaccaggtccagtcggaagaaaagagcaacgccaagagacccaagtttcaatggctgctctcgcaggaattccaaatc tgcctccgccacttcaagtttcataagctcaccctatacctctgtggatgaatattcttaattccatttcctgaggtaaa agattagtgtgagaccatcatggtgccagtctaggaccccattctcctatttatcagtcctgtcctatataccctctaga aacagaaagcaatttttaggcagctatggtcaaattgagaaaggtagtgtataaatgtgacaaagacactaataacatgt tagcctccacccaaaataaaatgggctttaaatttggtatatggctattattgatcccttgaaacccagactgtctgcta cagcaaccaagattgtcattggaagtatttggattctagcatttctacttgccttccctcagtgtctttattccaaaacc aaagtcatgccaggccgtactctctgctttgtgcaatggccagaaggtcccaaacaacatttcacgtaagttaattctct attatggttttcaattcagtttcatgtgtttttcttatttttcatagttaccatattatcgtcattatactggtgtactg tttcccattgctcatcatgggtattacatacaccattgttggaattactctctggggaggagaaatcccaggagatacct gtgacaagtatcatgagcagctaaaggccaaaagaaaggtactggtccatgttgtttacctagcaaatgactttttcttt ataggttgtcaaaatgatgattattgttgtcatgacatttgctatctgctggctgccctatcatatttacttcattctca ctgcaatctatcaacaactaaatagatggaaatapatccagcaggtctacctggctagcttttggctggcaatgagctca accatgtacaatcccatcatctactgctgtctgaataaaaggtaaaaacaaaactacgaaatgcaagttgcttgtcacaa aataacttttctttctgtggcctgcttttcctcagatttcgagctggcttcaagagagcatttcgctggtgtcctttcat caaagtttccagctatgatgagctagagctcaagaccaccaggtttcatccaaaccggcaaagcagtatgtacaccgtga ccagaatggagtccatgacagtcgtgtttgaccccaacgatgcagacaccaccaggtccagtcggaagaaaagagcaacg ccaagagacccaagtttcaatggctgctctcgcaggaattccaaatctgcctccgccacttcaagtttcataagctcacc ctatacctctgtggatgaatattcttaattccatttcctgaggtaaaagattagtgtgagaccatcatggtgccagtcta ggaccccattctcctatttatcagtcctgtcctatataccctctaga (SEQ ID NO: 12318) ctagtctttcagccttcaggctgtttttggcttgaagctctcttggcctcctagtttctacctaatcatgtccctggtgg aggccatcagcctctggaatgaaggggtgctggcagcggacaagaaggactggaagggagccctggatgccttcagtgcc gtccaggacccccactcccggatttgcttcaacattggctgcatgtacactatcctgaagaacatgactgaagcagagaa ggcctttaccagaagcattaaccgagacaagcacttggcagtggcttacttccaacgagggatgctctactaccagacag agaaatatgatttggctatcaaagaccttaaagaagccttgattcagcttcgagggaaccagctgatagactataagatc ctggggctccagttcaagctgtttgcctgtgaggtgttatataacattgctttcatgtatgccaagaaggaggaatggaa aaaagctgaagaacagttagcattggccacgagcatgaagtctgagcccagacattccaaaatcgacaaggcgatggagt gtgtctggaagcagaagctatatgagccagtggtgatccctgtgggcaagctgtttcgaccaaatgagagacaagtggct cagctggccaagaaggattacctaggcaaggcgacggtcgtggcatctgtggtggatcaagacagtttctctgggtttgc ccctctgcaaccacaggcagctgagcctccacccagaccgaaaaccccagagatcttcagggctctggaaggggaggctc accgtgtgctatttgggtttgtgcctgagacaaaagaagagctccaggtcatgccagggaacattgtctttgtcttgaag aagggcaatgataactgggccacggtcatgttcaacgggcagaaggggcttgttccctgcaactaccttgaaccagttga gttgcggatccaccctcagcagcagccccaggaggaaagctctccgcagtccgacatcccagctcctcctagttccaaag cccctggaaaaccccagctgtcaccaggccagaaacaaaaagaagagcctaaggaagtgaagctcagtgttcccatgccc tacacactcaaggtgcactacaagtacacggtagtcatgaagactcagcccgggctcccctacagccaggtccgggacat ggtgtctaagaaactggagctccggctggaacacactaagctgagctatcggcctcgggacagcaatgagctggtgcccc tttcagaagacagcatgaaggatgcctggggccaggtgaaaaactactgcctgactctgtggtgtgagaacacagtgggt gaccaaggctttccagatgaacccaaggaaagtgaaaaagctgatgctaataaccagacaacagaacctcagcttaagaa aggcagccaagtggaggcactcttcagttatgaggctacccaaccagaggacctggagtttcaggaaggggatataatcc tggtgttatcaaaggtgaatgaagaatggctggaaggggagtgcaaagggaaggtgggcattttccccaaagtttttgtt gaagactgcgcaactacagatttggaaagcactcggagagaagtctaggatgtttcacaaactacaaagctgaagaaaat gaagccctattacttgtttgtaagatttagcacccttctgctgtatactgtactgagacattacagtttggaagtgttaa ctatttattccctgttaaaatttaacctactagacaatgatgtgagtacccaggatgatttcctggggcacagtgggtga ggagatggggacaggtgaatggaggagttaggggagaggaaaagtggatggaagtgtctggaaagggcacgagagagtct tccaggtactgatcctgtttcttgctctgagtgctagctagccagctgtgttcacactgtaaacattcatcaagctgtac atttggtgcacttttctgtgtcataccacaataaaaaaaaacctatcatcatcttacaaaaacaagacacccaagtccag gcccaaggagtaagtacaaatattcctgtttctgaaccattactgtaattggctcttaaggcttgaagtaaccttatagg ttactcataaggcatatacaaataaacttgtttgttttcttttttc (SEQ ID NO: 12319) ctagtctttcagccttcaggctgtttttggcttgaagctctcttggcctcctagtttc acctaatcatgtccctggtgg aggccatcagcctctggaatgaaggggtgctggcagcggacaagaaggactggaagggagccctggatgccttcagtgcc gtccaggacccccactcccggatttgcttcaacattggctgcatgtacactatcctgaagaacatgactgaagcagagaa ggcctttaccagaagcattaaccgagacaagcacttggcagtggcttacttccaacgagggatgctctactaccagacag agaaatatgatttggctatcaaagaccttaaagaagccttgattcagcttcgagggaaccagctgatagactataagatc ctggggctccagttcaagctgtttgcctgtgaggtgttatataacattgctttcatgtatgccaagaaggaggaatggaa aaaagctgaagaacagttagcattggccacgagcatgaagtctgagcccagacattccaaaatcgacaaggcgatggagt gtgtctggaagcagaagctatatgagccagtggtgatccctgtgggcaagctgtttcgaccaaatgagagacaagtggct cagctggccaagaaggattacctaggcaaggcgacggtcgtggcatctgtggtggatcaagacagtttctctgggtttgc ccctctgcaaccacaggcagctgagcctccacccagaccgaaaaccccagagatcttcagggctctggaaggggaggctc accgtgtgctatttgggtttgtgcctgagacaaaagaagagctccaggtcatgccagggaacattgtctttgtcttgaag aagggcaatgataactgggccacggtcatgttcaacgggcagaaggggcttgttccctgcaactaccttgaaccagttga gttgcggatccaccctcagcagcagccccaggaggaaagctctccgcagtccgacatcccagctcctcctagttccaaag cccctggaaaaccccagctgtcaccaggccagaaacaaaaagaagagcctaaggaagtgaagctcagtgttcccatgccc tacacactcaaggtgcactacaagtacacggtagtcatgaagactcagcccgggctcccctacagccaggtccgggacat ggtgtctaagaaactggagctccggctggaacacactaagctgagctatcggcctcgggacagcaatgagctggtgcccc tttcagaagacagcatgaaggatgcctggggccaggtgaaaaactactgcctgactctgtggtgtgagaacacagtgggt gaccaaggctttccagatgaacccaaggaaagtgaaaaagctgatgctaataaccagacaacagaacctcagcttaagaa aggcagccaagtggaggcactcttcagttatgaggctacccaaccagaggacctggagtttcaggaaggggatataatcc tggtgttatcaaaggtgaatgaagaatggctggaaggggagtgcaaagggaaggtgggcattttccccaaagtttttgtt gaagactgcgcaactacagatttggaaagcactcggagagaagtctaggatgtttcacaaactacaaagctgaagaaaat gaagccctattacttgtttgtaagatttagcacccttctgctgtatactgtactgagacattacagtttggaagtgttaa ctatttattccctgttaaaatttaacctactagacaatgatgtgagtacccaggatgatttcctggggcacagtgggtga ggagatggggacaggtgaatggaggagttaggggagaggaaaagtggatggaagtgtctggaaagggcacgagagagtct tccaggtactgatcctgtttcttgctctgagtgctagctagccagctgtgttcacactgtaaacattcatcaagctgtac atttggtgcacttttctgtgtcataccacaataaaaaaaaacctatcatcatcttacaaaaacaagacacccaagtccag gcccaaggagtaagtacaaatattcctgtttctgaaccattactgtaattggctcttaaggcttgaagtaaccttatagg ttactcataaggcatatacaaataaacttgtttgttttcttttttc (SEQ ID NO:12320) gcagagctgggcaccacagggagctaggctctgtgagccgtggctcatctcacacctcctcactgccttgcatcatggcc atgtctggacccttctctcctcaggcctttaccagaagcattaaccgagacaagcacttggcagtggcttacttccaacg agggatgctctactaccagacagagaagtaagtggttcaatgttgcaccaactggaggatttcagagagaaacccaaggg gtctcagtgttgcgggcttggtgtttgagcagt (SEQ ID NO: 12321) ggtcagaaggaactgaaaggcttcttgtcccagtgagatagctggggaagggagaagcagactcacattttatgctgcat ttatttctccatccactagactgctgattttctccctctgtcctggagatatgatttggctatcaaagaccttaaagaag ccttgattcagcttcgagggaaccagctgatagactataagatcctggggctccagttcaagctgtttgcctgtgaggta aggagaacagggcctggctgggcaggaggggatcatggctggatggatggctgacagtcagatgcacagtgatctgttga cacctccaggagcttggaaaagccatttctcctctgccttgagactcagattttccttgaagaaaagactgagatggatt atttcaggctcatcaaggca (SEQ ID NO: 12322) ttccctggcaccttgatttggagtagtctcaagttttatgtttgcggtctgtacttttctaggtgttatataacattgct ttcatg atgccaagaaggaggaatggaaaaaagctgaagaacagttagcattggccacgagcatgaagtctgagcccag acattccaaaatcgacaaggcgatggagtgtgtctgggtaagcgtattggtgatgcaggtgttgagaggatgtcactgga ttctcatttgtctcagaggacatgccattgagaagccataaaagtggtgcttttactttctgtgagtctgggtaacactg atcttagggtatagttccacttaagatcttgaatctgtgctgagaagctgaggcctagagtatgggatggcagagcctgg catcacaccacccttggagtggggctccttggcaatgcaggagaacaggatattggatgctggagcagtgctgcacagac tctaagcactgagagggcagagtccatgtctgcttgatcaccactgagtcctcacagcctggcacagtgctaggccacat aacagctctcagcaaaaatgttttgttttgttttgagatggagtctcgctctgttgcccagcctggagtgcagtggtgtg atctcagctcactgcagcctctgcctcctgggttcaagcaattctgctgcctcagccgcccaagtagctgggattacagg tgcatgccaccatgcctggctaatttttgtatttttaatagagacggggttttgccatgt (SEQ ID NO-.12323) gaattcttgcatctattcactgagggaggcaggacaagcatcgtcacccccattttcacataagggaatgctacgttttc tgtgttacagaagcagaagctatatgagccagtggtgatccctgtgggcaagctgtttcgaccaaatgagagacaagtgg ctcagctggccaagaaggattacctaggcaaggcgacggtaggtgggattgctcagcttcccctgagtcttcctgtggcc cgggcatgtggagcaaggtgggagggactcttgagaag (SEQ ID Nθ:12324) gcaggagaatcacttgaacctggaaggcagaggttgcagtgagctgagtcactccactgcactccagtctgggtaacaga gcgtgctccgtctcaaaaaaaaaaaaaaaaaaaaagataatttgatgttatacaaattgcacctcaattaaaaacatttc ttttttaagagagaagaaagcaagcctgtgttagcaggggtggggtgaatgctcgtttcttcagttgctgaaatcctaat ccagaggctcaggaatctaatccttagttactgtccacgtctgaaaccaggctcacgtaagaacaggtctagggcatgag caaagagggagacccagaagaatggaaacagtgctggcagagcctcacaccctcctgtccttgattttaggtcgtggcat ctgtggtggatcaagacagtttctctgggtttgcccctctgcaaccacaggtaaggcagtcctgaccttctccatggacc taggtctcgagagctttctgtgaagcattcaattcgagagactatgtgtgctgagttgcctgattgtaagggctccttca agtggccctcagtgcagctgaggattctgcctgccctctctcagtcctggtttccatggctggtgaggaaataaggcagt gtcaggcttcaccccaagtcctctgaagctaactctcctgcttccccacaaatgccggtcttcac (SEQ ID NO: 12325) actgaattgctgtgctagtgaaacctgtacctgggagctggtgggaggtgttatttcccagtgtttagtcagggtgactg tgccctcttcctagacagtgttctcatcagtcagaaatgcgttatttgattttctggtctggaagaatgctcaaattacc attagccgtttgttgtctctcccctgctttccctcattgccttttccgttttcacttctcctgaatgttcaataggcagc tgagcctccacccagaccgaaaaccccagagatcttcaggtaagttagattcaaatccataaatagaatatcaagcgcca agcctgagctgatggcaagaaagggagggaagaagatgaaggtggggtcagggtctaaatcttgttgaattttctggaat gtcaggcttcttctagaatgtcaggctagaaaggaatgcctagaagaatgtcttctagaatgtcaggctagaaaggaatg atatatggggatgggagtcttgactgtggtggggctggccatcagggcttggctgcagctacgtggtccattggccctct gtccacgtgcacagccaccacatgcaggggttgtgctgagggcagtgtgtcctgtggaacatagctacctgggaccagat gctgacctcaggttggagatcggtttcgcactggctgcagtcctctgacggggcaggccagagctctct (SEQ ID N0:12326) tgagcagtgtacaccagtttcttgctgagacctcttggacccaggcaggctcagtgtcatctcggcagttgcagttagat gtggagttagagccaggctgagccaagtccctggctccaagttcagtgtatttgcgccatggcatcatgtgaggggatgg gggctggatcttgtgtctatcctctgcagggctctggaaggggaggctcaccgtgtgctatttgggtttgtgcctgagac aaaagaagagctccaggtcatgccagggaacattgtctttgtcttgaagaagggcaatgataactgggccacggtcatgt tcaacgggcaggtatgcagaggatcaggggctggtgcgatgggcatgggatcctggcagcaaatgcagtctctgtggagc agtatctgctgccttctttgcagaccagccaagttcttttgtctgttcgtcatcccttccccaggactctgggctgttct gtggtgtgggtactgatgagcacatctttattttttcctttctgattctgtggtgctgcactgcagaaggggcttgttcc ctgcaactaccttgaaccagttgagctgcggatccaccctcagcagcagccccaggtaatgtgatgccaaggcctgaccc atttcctctcaccctttaggatctctccctggagggagaaaagcagtgtaaaagaggtgttgtcaggacccctggagaaa gattcactagtcttgagcccgccttgagatggcaccagctacccagagctgaacctgggaatgaggggaaaaaagcccag atgtgctaagttggaggcatctgtaggtcccattggcccacccacctct (SEQ ID NO.- 12327) aatgtcactaccattccaacttttaggacgttatctgcatgtggctcctttacatggggtctctgtaggggtgtttcccc acatccacccctgcctgggaactttgaatgaaggttctgaccatcgctccctgttgccttcaggaggaaagctctccgca gtccgacatcccagctcctcctagttccaaagcccctggaagaccccagctgtcaccaggtgagtggtcctggagccaca gcctaggtttgggtgcagcagcatgccaggtgttcctgagttcctctccctgccttccaggaaattct (SEQ ID NO: 12328) gactgagtttgttcatgtgttcatgaccttcatgcttccccagggcgagatttccccacagtttactaaggttaataatt gccccacaaattaaagggtaagaggttgggggccctatttgaagaggtttcatctgtgtgtggcaggggctggccaagga tgttcattcaccatcttcttttgttttactccctactttttccattcaggccagaaacaaaaagaagagcctaaggtaac atttttccctcatactgtttcaagtggtagaagatgggatagcttgggctatcaaccacagacatgtctgtctggattat aggaagagcccaaaggagggtcgaaccagttgctaccttacagagtccatgagctagggaccttcttaatagcctcctcc actatcatgcacacacttcctactacccaagctagtgggccagatcttactcagtaggaattc (SEQ ID NO: 12329) gaattcctgtccaagcaagggttgggctaaaggacctctgaaggccttttaggctactgtgaaaccagttacttactggc ctctcccctgctgtattgggtaccccctgtgccaaatcacgaaactgcggtgatccaggatgttgagagaaagcctcaga cactcaggagttccctttgtttcctccccactcaggaagtgaagctcagtgttcccatgccctacacactcaaggtgcac tacaagtacacggtagtcatgaagactcagcccgggctcccctacagccaggtccgggacatggtgtctaagaaactgga gctccggctggaacacactaagctgaggtgagctccatgcaggcagctgtgaggggtacagtgggaaccttgtgctggcc tggaggagggaagaggaggatggtttttgtgatgatgttctttgactggattcttactcattatccccacccagctatcg gcctcgggacagcaatgagctggtgcccctttcagaagacagcatgaaggatgcctggggccaggtgaaaaactactgcc tgactctgtggtgtgagaacacagtggtgagtgcaatgaggggcatctaaagttacatttccactgagccacttcctcaa caatttgaaatttatcaagcaccttctgtgtactaggcactatatgtggtgttggggatatggtgtgtaataagtcacag ctctgcctcccttttacctgcatcctcaccccatttgcagcagggagagagtttcccacaagag (SEQ ID NO: 12330) ttcataaagagcatataagctctacacaaggcactgatcacaaactttatgagtttatatcccaggttctactttgacat ttcgctgtttcctttagtgatgttcagtgttcacttggcaggaaattgggaaaattaacaggccctttattatttcaggg tgaccaaggctttccagatgaacccaaggaaagtgaaaaagctgatgctaataaccagacaacagaacctcagcttaaga aaggcagccaagtggaggcactcttcagttatgaggctacccaaccagaggacctggagtttcaggaaggggatataatc ctggtgttatcaaagggtaagtgctactccaagactatagaaacaaatttacatgttagcagaaacaaggtcaagggcag agagaagaaatatcaataatctacaaacaaaactttagccagtgttttca (SEQ ID NO: 12331) gtcaattcttgaccctcttctctatctggtaactttttgaaaaacataatttatcctctcttcattttgctcattatcat gtttaagacagatcaataagatggttaaaccctgtgttcactctcaaaccactttgcaatactgtcttttccctgttgat cacaattaggggtggggaagggtgaccgataacaaattctgtgtggaatagccagacagggtaatcttcctacagtggtt ttagaaatccatgtgtacttttccttttatcagtgaatgaagaatggctggaaggggagtgcaaagggaaggtgggcatt ttccccaaagtttttgttgaagactgcgcaactacagatttggaaagcactcggagagaagtctaggatgtttcacaaac tacaaagctgaagaaaatgaagccctattacttgtttgtaagatttagcacccttctgctgtatactgtactgagacatt acagtttggaagtgttaactatttattccctgttaaaatttaacctactagacaatgatgtgagtacccaggatgatttc ctggggcacagtgggtgaggagatggggacaggtgaatggaggagttaggggagaggaaaagtggatggaagtgtctgga aagggcacgagagagtcttccaggtactgatcctgtttcttgctctgagtgctagctagccagctgtgttcacactgtaa acattcatcaagctgtacatttggtgcacttttctgtgtcataccacaataaaaaaaaacctatcatcttacaaaaacaa gacacccaagtccaggcccaaggagtaagtacaaatat cctgtttctgaaccattactgtaattggctcttaaggcttg aagtaaccttataggttactcataaggcatatacaaataaacttgtttgttttcttttttcattatgtcttgttgcttaa acagaacctagactgagttaggttctcatggactacaacactcaattccacagagaattaatagaattacatacctttgt acattctcagagaggaacatgtgttaagaactcaatactgaatatatatcaatcgccaacatttaagtgatgaaaagcag cggtgttcatgaagctagttcgtaa (SEQ ID Nθ:12332) gtcacatcgccctgctgggctttgagaagcgcttcgtacccagccagcactatgtgtacatgttcctggtgaaat (SEQ ID NO: 12333) ctagtctttcagccttcaggctgtttttggcttgaagctctcttggcctcctagtttctacctaatcatgtccctggtgg aggccatcagcctctggaatgaaggggtgctggcagcggacaagaaggactggaagggagccctggatgccttcagtgcc gtccaggacccccactcccggatttgcttcaacattggctgcatgtacactatcctgaagaacatgactgaagcagagaa ggcctttaccagaagcattaaccgagacaagcacttggcagtggcttacttccaacgagggatgctctact ccagacag agaaatatgatttggctatcaaagaccttaaagaagccttgattcagcttcgagggaaccagctgatagactataagatc ctggggctccagttcaagctgtttgcctgtgaggtgttatataacattgctttcatgtatgccaagaaggaggaatggaa aaaagctgaagaacagttagcattggccacgagcatgaagtctgagcccagacattccaaaatcgacaaggcgatggagt gtgtctggaagcagaagctatatgagccagtggtgatccctgtgggcaagctgtttcgaccaaatgagagacaagtggct cagctggccaagaaggattacctaggcaaggcgacggtcgtggcatctgtggtggatcaagacagtttctctgggtttgc ccctctgcaaccacaggcagctgagcctccacccagaccgaaaaccccagagatcttcagggctctggaaggggaggctc accgtgtgctatttgggtttgtgcctgagacaaaagaagagctccaggtcatgccagggaacattgtctttgtcttgaag aagggcaatgataactgggccacggtcatgttcaacgggcagaaggggcttgttccctgcaactaccttgaaccagttga gttgcggatccaccctcagcagcagccccaggaggaaagctctccgcagtccgacatcccagctcctcctagttccaaag cccctggaaaaccccagctgtcaccaggccagaaacaaaaagaagagcctaaggaagtgaagctcagtgttcccatgccc tacacactcaaggtgcactacaagtacacggtagtcatgaagactcagcccgggctcccctacagccaggtccgggacat ggtgtctaagaaactggagctccggctggaacacactaagctgagctatcggcctcgggacagcaatgagctggtgcccc tttcagaagacagcatgaaggatgcctggggccaggtgaaaaactactgcctgactctgtggtgtgagaacacagtgggt gaccaaggctttccagatgaacccaaggaaagtgaaaaagctgatgctaataaccagacaacagaacctcagcttaagaa aggcagccaagtggaggcactcttcagttatgaggctacccaaccagaggacctggagtttcaggaaggggatataatcc tggtgttatcaaaggtgaatgaagaatggctggaaggggagtgcaaagggaaggtgggcattttccccaaagtttttgtt gaagactgcgcaactacagatttggaaagcactcggagagaagtctaggatgtttcacaaactacaaagctgaagaaaat gaagccctattacttgtttgtaagatttagcacccttctgctgtatactgtactgagacattacagtttggaagtgttaa ctatttattccctgttaaaatttaacctactagacaatgatgtgagtacccaggatgatttcctggggcacagtgggtga ggagatggggacaggtgaatggaggagttaggggagaggaaaagtggatggaagtgtctggaaagggcacgagagagtct tccaggtactgatcctgtttcttgctctgagtgctagctagccagctgtgttcacactgtaaacat catcaagctgtac atttggtgcacttttctgtgtcataccacaataaaaaaaaacctatcatcatcttacaaaaacaagacacccaagtccag gcccaaggagtaagtacaaatattcctgtttctgaaccattactgtaattggctcttaaggcttgaagtaaccttatagg t actcataaggcatatacaaataaacttgtttgttttcttttttcctagtctttcagccttcaggctgtttttggcttg aagctctcttggcctcctagtttctacctaatcatgtccctggtggaggccatcagcctctggaatgaaggggtgctggc agcggacaagaaggactggaagggagccctggatgccttcagtgccgtccaggacccccactcccggatttgcttcaaca ttggctgcatgtacactatcctgaagaacatgactgaagcagagaaggcctttaccagaagcattaaccgagacaagcac ttggcagtggcttacttccaacgagggatgctctactaccagacagagaaatatgatttggctatcaaagaccttaaaga agccttgattcagcttcgagggaaccagctgatagactataagatcctggggctccagttcaagctgtttgcctgtgagg tgttatataacattgctttcatgtatgccaagaaggaggaatggaaaaaagctgaagaacagttagcattggccacgagc atgaagtctgagcccagacattccaaaatcgacaaggcgatggagtgtgtctggaagcagaagctatatgagccagtggt ga ccctgtgggcaagctgtttcgaccaaatgagagacaagtggctcagctggccaagaaggattacctaggcaaggcga cggtcgtggcatctgtggtggatcaagacagtttctctgggtttgcccctctgcaaccacaggcagctgagcctccaccc agaccgaaaaccccagagatcttcagggctctggaaggggaggctcaccgtgtgctatttgggtttgtgcctgagacaaa agaagagctccaggtcatgccagggaacattgtctttgtcttgaagaagggcaatgataactgggccacggtcatgttca acgggcagaaggggcttgttccctgcaactaccttgaaccagttgagttgcggatccaccctcagcagcagccccaggag gaaagctctccgcagtccgacatcccagctcctcctagttccaaagcccctggaaaaccccagctgtcaccaggccagaa acaaaaagaagagcctaaggaagtgaagctcagtgttcccatgccctacacactcaaggtgcactacaagtacacggtag tcatgaagactcagcccgggctcccctacagccaggtccgggacatggtgtctaagaaactggagctccggctggaacac actaagctgagctatcggcctcgggacagcaatgagctggtgcccctttcagaagacagcatgaaggatgcctggggcca ggtgaaaaactactgcctgactctgtggtgtgagaacacagtgggtgaccaaggctttccagatgaacccaaggaaagtg aaaaagctgatgctaataaccagacaacagaacctcagcttaagaaaggcagccaagtggaggcactcttcagttatgag gctacccaaccagaggacctggagtttcaggaaggggatataatcctggtgttatcaaaggtgaatgaagaatggctgga aggggagtgcaaagggaaggtgggcattttccccaaagtttttgttgaagactgcgcaactacagatttggaaagcactc ggagagaagtctaggatgtttcacaaactacaaagctgaagaaaatgaagccctattacttgtttgtaagatttagcacc cttctgctgtatactgtactgagacattacagtttggaagtgttaactatttattccctgttaaaatttaacctactaga caatgatgtgagtacccaggatgatttcctggggcacagtgggtgaggagatggggacaggtgaatggaggagttagggg agaggaaaagtggatggaagtgtctggaaagggcacgagagagtcttccaggtactgatcctgtttcttgctctgagtgc tagctagccagctgtgttcacactgtaaacattcatcaagctgtacatttggtgcacttttctgtgtcataccacaataa aaaaaaacctatcatcatcttacaaaaacaagacacccaagtccaggcccaaggagtaagtacaaatattcctgtttctg aaccattactgtaattggctcttaaggcttgaagtaaccttataggttactcataaggcatatacaaataaacttgtttg ttttcttttttcgcagagctgggcaccacagggagctaggctctgtgagccgtggctcatctcacacctcctcactgcct tgcatcatggccatgtctggacccttctctcctcaggcctttaccagaagcattaaccgagacaagcacttggcagtggc ttacttccaacgagggatgctctactaccagacagagaagtaagtggttcaatgttgcaccaactggaggatttcagaga gaaacccaaggggtctcagtgttgcgggcttggtgtttgagcagtggtcagaaggaactgaaaggcttcttgtcccagtg agatagctggggaagggagaagcagactcacattttatgctgcatttatttctccatccactagactgctgattttctcc ctctgtcctggagatatgatttggctatcaaagaccttaaagaagccttgattcagcttcgagggaaccagctgatagac tataagatcctggggctccagttcaagctgtttgcctgtgaggtaaggagaacagggcctggctgggcaggaggggatca tggctggatggatggctgacagtcagatgcacagtgatctgttgacacctccaggagcttggaaaagccatttctcctct gccttgagactcagattttccttgaagaaaagactgagatggattatttcaggctcatcaaggcattccctggcaccttg atttggagtagtctcaagttttatgtttgcggtctgtacttttctaggtgttatataacattgctttcatgtatgccaag aaggaggaatggaaaaaagctgaagaacagttagcattggccacgagcatgaagtctgagcccagacattccaaaatcga caaggcgatggagtgtgtctgggtaagcgtattggtgatgcaggtgttgagaggatgtcactggattctcatttgtctca gaggacatgccattgagaagccataaaagtggtgcttttactttctgtgagtctgggtaacactgatcttagggtatagt tccacttaagatcttgaatctgtgctgagaagctgaggcctagagtatgggatggcagagcctggcatcacaccaccctt ggagtggggctccttggcaatgcaggagaacaggatattggatgctggagcagtgctgcacagactctaagcactgagag ggcagagtccatgtctgcttgatcaccactgagtcctcacagcctggcacagtgctaggccacataacagctctcagcaa aaatgttttgttttgttttgagatggagtctcgctctgttgcccagcctggagtgcagtggtgtgatctcagctcactgc agcctctgcctcctgggttcaagcaattctgctgcctcagccgcccaagtagctgggattacaggtgcatgccaccatgc ctggctaatttttgtatttttaatagagacggggttttgccatgtgaattcttgcatctattcactgagggaggcaggac aagcatcgtcacccccattttcacataagggaatgctacgttttctgtgttacagaagcagaagctatatgagccagtgg tgatccctgtgggcaagctgtttcgaccaaatgagagacaagtggctcagctggccaagaaggattacctaggcaaggcg acggtaggtgggattgctcagcttcccctgagtcttcctgtggcccgggcatgtggagcaaggtgggagggactcttgag aaggcaggagaatcacttgaacctggaaggcagaggttgcagtgagctgagtcactccactgcactccagtctgggtaac agagcgtgctccgtctcaaaaaaaaaaaaaaaaaaaaagataatttgatgttatacaaattgcacctcaattaaaaacat ttcttttttaagagagaagaaagcaagcctgtgttagcaggggtggggtgaatgctcgtttcttcagttgctgaaatcct aatccagaggctcaggaatctaatccttagttactgtccacgtctgaaaccaggctcacgtaagaacaggtctagggcat gagcaaagagggagacccagaagaatggaaacagtgctggcagagcctcacaccctcctgtccttgattttaggtcgtgg catctgtggtggatcaagacagtttctctgggtttgcccctctgcaaccacaggtaaggcagtcctgaccttctccatgg acctaggtctcgagagctttctgtgaagcattcaattcgagagactatgtgtgctgagttgcctgattgtaagggctcct tcaagtggccctcagtgcagctgaggattctgcctgccctctctcagtcctggtttccatggctggtgaggaaataaggc agtgtcaggcttcaccccaagtcctctgaagctaactctcctgcttccccacaaatgccggtcttcacacattcatcaag ctgtacatttggtgcacttttctgtgtcataccacaataaaaaaaaacctatcatcttacaaaaacaagacacccaagtc caggcccaaggagtaagtacaaatattcctgtttctgaaccattactgtaattggctcttaaggcttgaagtaaccttat aggttactcataaggcatatacaaataaacttgtttgttttcttttttcattatgtcttgttgcttaaacagaacctaga ctgagttaggttctcatggactacaacactcaattccacagagaattaatagaattacatacctttgtacattctcagag aggaacatgtgttaagaactcaatactgaatatatatcaatcgccaacatttaagtgatgaaaagcagcggtgttcatga agctagttcgtaagtcacatcgccctgctgggctttgagaagcgcttcgtacccagccagcactatgtgtacatgttcct ggtgaaat (SEQ ID NO: 12334) ccagctgatattccagcccacagcaatggagccacatgactcctcccacatggactctgagttccgatacactctcttcc cgattgtttacagcatcatctttgtgctcggggtcattgctaatggctacgtgctgtgggtctttgcccgcctgtaccct tgcaagaaattcaatgagataaagatcttcatggtgaacctcaccatggcggacatgctcttcttgatcaccctgccact ttggattgtctactaccaaaaccagggcaactggatactccccaaattcctgtgcaacgtggctggctgccttttcttca tcaacacctactgctctgtggccttcctgggcg catcacttataaccgcttccaggcagtaactcggcccatcaagact gctcaggccaacacccgcaagcgtggcatctctttgtccttggtcatctgggtggccattgtgggagctgcatcctactt cctcatcctggactctaccaacacagtgcccgacagtgctggctcaggcaacgtcactcgctgctttgagcattacgaga agggcagcgtgccagtcctcatcatccacatcttcatcgtgttcagcttcttcctggtcttcctcatcatcctcttctgc aacctggtcatcatccgtaccttgctcatgcagccggtgcagcagcagcgcaacgctgaagtcaagcgccgggcgctgtg gatggtgtgcacggtcttggcggtgttcatcatctgcttcgtgccccaccacgtggtgcagctgccctggacccttgctg agctgggcttccaggacagcaaattccaccaggccattaatgatgcacatcaggtcaccctctgcctccttagcaccaac tgtgtcttagaccctgttatctactgtttcctcaccaagaagttccgcaagcacctcaccgaaaagttctacagcatgcg cagtagccggaaatgctcccgggccaccacggatacggtcactgaagtggttgtgccattcaaccagatccctggcaatt ccctcaaaaattagtccttgcttc (SEQ ID NO:12335) ttcacgagggctggggccaggacccagacagagacacacggtcactgcagctgaagccgctgcccctgctacaggcacca ccaggaccagctgatcattccagcccacagcaatggagccacatgactcctcccacatggactctgagttccgatacact ctcttcccgattgtttacagcatcatctttgtgctcggggtcattgctaatggctacgtgctgtgggtctttgcccgcct gtacccttgcaagaaattcaatgagataaagatcttcatggtgaacctcaccatggcggacatgctcttcttgatcaccc tgccactttggattgtctactaccaaaaccagggcaactggatactccccaaattcctgtgcaacgtggctggctgcctt ttcttcatcaacacctactgctctgtggccttcctgggcgtcatcacttataaccgcttccaggcagtaactcggcccat caagactgctcaggccaacacccgcaagcgtggcatctctttgtccttggtcatctgggtggccattgtgggagctgcat cctacttcctcatcctggactccaccaacacagtgcccgacagtgctggctcaggcaacgtcactcgctgctttgagcat tacgagaagggcagcgtgccagtcctcatcatccacatcttcatcgtgttcagcttcttcctggtcttcctca catcct cttctgcaacctggtcatcatccgtaccttgctcatgcagccggtgcagcagcagcgcaacgctgaagtcaagcgccggg cgctgtggatggtgtgcacggtcttggcggtgttcatcatctgcttcgtgccccaccacgtggtgcagctgccctggacc cttgctgagctgggcttccaggacagcaaattccaccaggccattaatgatgcacatcaggtcaccctctgcctccttag caccaactgtgtcttagaccctgttatctactgtttcctcaccaagaagttccgcaagcacctcaccgaaaagttctaca gcatgcgcagtagccggaaatgctcccgggccaccacggatacggtcactgaagtggttgtgccattcaaccagatccct ggcaattccctcaaaaattagtccctgcttccaggcctgaagtcttctcctccatgaaacatcatgactgagctggggga agaagggatatctactgtgggtctgggcaccacctctgtggcactggtgggccattagatttggaggctacctcacctgg gcagggatgatgcagagccaggctgttggaaaatccagaactcaaatgagccccttcatccgcctgtgggcgcatactac agtaactgtgactgatgactttatcctgagtcccttaatcttatggggccggaaggaatgtcagggccaggtgcagacct tgggggaagactttaaaccacctagttctcccactggggcatcggtctaaagctttgggggagtggccccagtggctcac acctgtaatcccagcactttgggaggccgaggtgggcagatcatgggtcaagagatcgagacatcctggccaacattgta aaaccccatctctactaaaacatacaaaaattagccgggcatggtgcacacgcctgtagtcccagctactcaggaggctg aggcaggagaatcgcttgaacctgggaggcagaggttgcagtgaacctagattgcaccattgcactctagcctggcaaca gaggcagattccctcctgcc (SEQ ID NO: 12336) cgggaggcggaggttgcggtgagctgagatcacgccactgcactccagcctgggcagcaagagtgaaactccatctgaaa aaaaaaaaaagattcaacatgaacttctgaggggacatcatcattctaaccatggcaaggagtcttggaactgatgaaat ggaacagtcccttcttgtccctttattaaccagaatttttgtgtggtcttccaggcaccaccaggaccagctgatcattc cagcccacagcaatggagccacatgactcctcccacatggactctgagttccgatacactctcttcccgattgtttacag catcatctttgtgctcggggtcattgctaatggctacgtgctgtgggtctttgcccgcctgtacccttgcaagaaat ea atgagataaagatcttcatggtgaacctcaccatggcggacatgctcttcttgatcaccctgccactttggattgtctac taccaaaaccagggcaactggatactccccaaattcctgtgcaacgtggctggctgccttttcttca caacacctactg ctctgtggccttcctgggcgtcatcacttataaccgcttccaggcagtaactcggcccatcaagactgctcaggccaaca cccgcaagcgtggcatctctttgtccttggtcatctgggtggccattgtgggagctgcatcctacttcctcatcctggac tccaccaacacagtgcccgacagtgctggctcaggcaacgtcactcgctgctttgagcattacgagaagggcagcgtgcc agtcctcatcatccacatcttcatcgtgttcagcttcttcctggtcttcctcatcatcctcttctgcaacctggtcatca tccgtaccttgctcatgcagccggtgcagcagcagcgcaacgctgaagtcacaggccgggcgctgtggatggtgtgcacg gtcttggcggtgt catcatctgcttcgtgccccaccacgtggtgcagctgccctggacccttgctgagctgggcttcca ggacagcaaattccaccaggccattaatgatgcacatcaggtcaccctctgcctccttagcaccaactgtgtcttagacc ctgttatctactgtttcctcaccaagaagttccgcaagcacctcaccgaaaagttctacagcatgcgcagtagccggaaa tgctcccgggccaccacggatacggtcactgaagtggttgtgccattcaaccagatccctggcaattccctcaaaaatta gtccctgcttccaggcctgaagtcttctcctccatgaacatcatggactgagctgggggaagaagggatatctactgtgg tctgggcaccacctctgtgggcactggtgggccattagatttggaggctacctcacctgggcagggatgatggcagacga ggctgttggaaaatccagaactcaaat (SEQ ID NO: 12337) ccagctgatattccagcccacagcaatggagccacatgactcctcccacatggactctgagttccgatacactctcttcc cgattgtttacagcatcatctttgtgctcggggtcattgctaatggctacgtgctgtgggtctttgcccgcctgtaccct tgcaagaaattcaatgagataaagatcttcatggtgaacctcaccatggcggacatgctcttcttgatcaccctgccact ttggattgtctactaccaaaaccagggcaactggatactccccaaattcctgtgcaacgtggctggctgccttttcttca tcaacacctactgctctgtggccttcctgggcgtcatcacttataaccgcttccaggcagtaactcggcccatcaagact gctcaggccaacacccgcaagcgtggcatctctttgtccttggtcatctgggtggccattgtgggagctgcatcctactt cctcatcctggactctaccaacacagtgcccgacagtgctggctcaggcaacgtcactcgctgctttgagcattacgaga agggcagcgtgccagtcctcatcatccacatcttcatcgtgttcagcttcttcctggtcttcctcatcatcctcttctgc aacctggtcatcatccgtaccttgctcatgcagccggtgcagcagcagcgcaacgctgaagtcaagcgccgggcgctgtg gatggtgtgcacggtcttggcggtgtteatcatctgcttcgtgccccaccacgtggtgcagctgccctggacccttgctg agctgggcttccaggacagcaaattccaccaggccattaatgatgcacatcaggtcaccctctgcctccttagcaccaac tgtgtcttagaccctgttatctactgtttcctcaccaagaagttccgcaagcacctcaccgaaaagttctacagcatgcg cagtagccggaaatgctcccgggccaccacggatacggtcactgaagtggttgtgccattcaaccagatccctggcaatt ccctcaaaaattagtccttgcttcttcacgagggctggggccaggacccagacagagacacacggtcactgcagctgaag ccgctgcccctgctacaggcaccaccaggaccagctgatcattccagcccacagcaatggagccacatgactcctcccac atggactctgagttccgatacactctcttcccgattgtttacagcatcatctttgtgctcggggtcattgctaatggcta cgtgctgtgggtctttgcccgcctgtacccttgcaagaaattcaatgagataaagatcttcatggtgaacctcaccatgg cggacatgctcttcttgatcaccctgccactttggattgtctactaccaaaaccagggcaactggatactccccaaattc ctgtgcaacgtggctggctgccttttcttcatcaacacctactgctctgtggccttcctgggcgtcatcacttat accg cttccaggcagtaactcggcccatcaagactgctcaggccaacacccgcaagcgtggcatctctttgtccttggtcatct gggtggccattgtgggagctgcatcctacttcctcatcctggactccaccaacacagtgcccgacagtgctggctcaggc aacgtcactcgctgctttgagcattacgagaagggcagcgtgccagtcctcatcatccacatcttcatcgtgttcagctt cttcctggtcttcctca ca cctcttctgcaacctggtcatcatccgtaccttgctcatgcagccggtgcagcagcagc gcaacgctgaagtcaagcgccgggcgctgtggatggtgtgcacggtcttggcggtgttcatcatctgcttcgtgccccac cacgtggtgcagctgccctggacccttgctgagctgggcttccaggacagcaaattccaccaggccattaatgatgcaca tcaggtcaccctctgcctccttagcaccaactgtgtcttagaccctgttatctactgtttcctcaccaagaagttccgca agcacctcaccgaaaagttctacagcatgcgcagtagccggaaatgctcccgggccaccacggatacggtcactgaagtg gttgtgccattcaaccagatccctggcaattccctcaaaaattagtccctgcttccaggcctgaagtcttctcctccatg aaacatcatgactgagctgggggaagaagggatatctactgtgggtctgggcaccacctctgtggcactggtgggccatt agatttggaggctacctcacctgggcagggatgatgcagagccaggctgttggaaaatccagaactcaaatgagcccctt catccgcctgtgggcgcatactacagtaactgtgactgatgactttatcctgagtcccttaatcttatggggccggaagg aatgtcagggccaggtgcagaccttgggggaagactttaaaccacctagttctcccactggggcatcggtctaaagcttt gggggagtggccccagtggctcacacctgtaatcccagcactttgggaggccgaggtgggcagatcatgggtcaagagat cgagacatcctggccaacattgtaaaaccccatctctactaaaacatacaaaaattagccgggcatggtgcacacgcctg tagtcccagc actcaggaggctgaggcaggagaatcgcttgaacctgggaggcagaggttgcagtgaacctagattgca ccattgcactctagcctggcaacagaggcagattccctcctgcccgggaggcggaggttgcggtgagctgagatcacgcc actgcactccagcctgggcagcaagagtgaaactccatctgaaaaaaaaaaaaagattcaacatgaacttctgaggggac a atcattctaaccatggcaaggagtcttggaactgatgaaatggaacagtcccttcttgtccctttat aaccagaat ttttgtgtggtcttccaggcaccaccaggaccagctgatcattccagcccacagcaatggagccacatgactcctcccac atggactctgagttccgatacactctcttcccgattgtttacagcatcatctttgtgctcggggtcattgctaatggcta cgtgctgtgggtctttgcccgcctgtacccttgcaagaaattcaatgagataaagatcttcatggtgaacctcaccatgg cggacatgctcttcttgatcaccctgccactttggattgtctactaccaaaaccagggcaactggatactccccaaattc ctgtgcaacgtggctggctgccttttcttcatcaacacctactgctctgtggccttcctgggcgtcatcacttataaccg cttccaggcagtaactcggcccatcaagactgctcaggccaacacccgcaagcgtggcatctctttgtccttggtcatct gggtggccattgtgggagctgcatcctacttcctcatcctggactccaccaacacagtgcccgacagtgctggctcaggc aacgtcactcgctgctttgagcattacgagaagggcagcgtgccagtcctcatcatccacatcttcatcgtgttcagctt cttcctggtcttcctcatcatcctcttctgcaacctggtcatcatccgtaccttgctcatgcagccggtgcagcagcagc gcaacgctgaagtcacaggccgggcgctgtggatggtgtgcacggtcttggcggtgttcatcatctgcttcgtgccccac cacgtggtgcagctgccctggacccttgctgagctgggcttccaggacagcaaattccaccaggccattaatgatgcaca tcaggtcaccctctgcctccttagcaccaactgtgtcttagaccctgttatctactgtttcctcaccaagaagttccgca agcacctcaccgaaaagttctacagcatgcgcagtagccggaaatgctcccgggccaccacggatacggtcactgaagtg gttgtgccattcaaccagatccctggcaattccctcaaaaattagtccctgcttccaggcctgaagtcttctcctccatg aacatcatggactgagctgggggaagaagggatatctactgtggtctgggcaccacctctgtgggcactggtgggccatt agatttggaggctacctcacctgggcagggatgatggcagacgaggctgttggaaaatccagaactcaaat (SEQ ID NO:12338) ctcctcctgcacaccttccgcacacctccctcgctctcccacaccactggcaccaggccccgcacacctgctcggctgca ggagaatggctactcatcacacgctgtggatgggactggtcctgctggggctgctgggcggcctacaggcagcacccgag gcccaggtctccgtgcagcccaacttccagccggacaagttcctggggcgctggttcagcgcgggcctcgcctccaactc gagctggctccaggagaagaaggcagcgctgtccatgtgcaagtcggtggtggcccctgcggcggatggtggcttcaacc tgacctccaccttcctcaggaaaaaccagtgtgagacccgaaccatgctgctgcagcccggggactccctcggctcctac agctaccggagtccccactggggcagcacctactctgtgtcagtggtggagactgactacgaccactacgccctgctgta cagccagggcagcaagggccccggcgaggacttccgcatggccaccctctacagccgaacccagacccccagggctgagt taaaggagaaatttaccgccttctgcaaggcccagggcttcacagaggattccattgtcttcctgccccaaaccgataag . tgcatgacggaacaataggactccccagagctgaagctgggaccgcagccagccaggtgacccctgcgatctggatgttt ccgctctgttccttccccgagcccctgccccggctccccgccaaagcacccctgccccctcgggcttcctcctggctctg cggaataaactccggaagcaagtctgt (SEQ ID NO: 12339) ggagcaagaggtggttggggggggaccatggctgacgttttcccgggcaacgactccacggcgtctcaggacgtggccaa ccgcttcgcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatcgcgcgcttcttca agcagcccaccttctgcagccactgcaccgacttcatctgggggtttgggaaacaaggcttccagtgccaagtttgctgt tttgtggtccacaagaggtgccatgaatttgttactttttcttgtccgggtgcggataagggacccgacactgatgaccc caggagcaagcacaagttcaaaatccacacttacggaagccccaccttctgcgatcactgtgggtcactgctctatggac ttatccatcaagggatgaaatgtgacacctgcgatatgaacgttcacaagcaatgcgtcatcaatgtccccagcctctgc ggaatggatcacactgagaagagggggcggatttacctaaaggctgaggttgctgatgaaaagctccatgtcacagtacg agatgcaaaaaatctaatccctatggatccaaacgggctttcagatccttatgtgaagctgaaac tattcctgatccca agaatgaaagcaagcaaaaaaccaaaaccatccgctccacactaaatccgcagtggaatgagtcctttacattcaaattg aaaccttcagacaaagaccgacgactgtctgtagaaatctgggactgggatcgaacaacaaggaatgacttcatgggatc cctttcctttggagtttcggagctgatgaagatgccggccagtggatggtacaagttgcttaaccaagaagaaggtgagt actacaacgtacccattccggaaggggacgaggaaggaaacatggaactcaggcagaaattcgagaaagccaaacttggc cctgctggcaacaaagtcatcagtccctctgaagacaggaaacaaccttccaacaaccttgaccgagtgaaactcacgga cttcaatttcctcatggtgttgggaaaggggagttttggaaaggtgatgcttgccgacaggaagggcacagaagaactgt atgcaatcaaaatcctgaagaaggatgtggtgattcaggatgatgacgtggagtgcaccatggtagaaaagcgagtcttg gccctgcttgacaaacccccgttcttgacgcagctgcactcctgcttccagacagtggatcggctgtacttcgtcatgga atatgtcaacggtggggacctcatgtaccacattcagcaagtaggaaaatttaaggaaccacaagcagtattctatgcgg cagagatttccatcggattgttctttcttcataaaagaggaatcatttatagggatctgaagttagataacgtcatgttg gattcagaaggacatatcaaaattgctgactttgggatgtgcaaggaacacatgatggatggagtcacgaccaggacctt ctgtgggactccagattatatcgccccagagataatcgcttatcagccgtatggaaaatctgtggactggtgggcctatg gcgtcctgttgtatgaaatgcttgccgggcagcctccatttgatggtgaagatgaagacgagctatttcagtctatcatg gagcacaacgtttcctatccaaaatccttgtccaaggaggctgtttctatctgcaaaggactgatgaccaaacacccagc caagcggctgggctgtgggcctgagggggagagggacgtgagagagcatgccttcttccggaggatcgactgggaaaaac tggagaacagggagatccagccaccattcaagcccaaagtgtgtggcaaaggagcagagaactttgacaagttcttcaca cgaggacagcccgtcttaacaccacctgatcagctggttattgctaacatagaccagtctgattttgaagggttctcgta tgtcaacccccagtttgtgcaccccatcttacagagtgcagtatgaaactcaccagcgagaacaaacacctccccagccc ccagccctccccgcagtggaagtgaatccttaaccctaaaattttaaggccacggcttgtgtctgattccatatggaggc ctgaaaattgtagggttattagtccaaatgtgatcaactgttcagggtctctctcttacaaccaagaacattatcttagt ggaag (SEQ ID NO: 12340) cttatcacagttcaagtgatttccagaagttccagggcttctgagagaccatcaagggaactttaacaacttgacaaatg tccttgaagtaagatgcctcatctttagggaaaaatggggtttggatttctgcttaggcaaagtctcctgcagttcatcc ttctctgtcctcttcttgcttcaggcttggggaccgtccctgctgtccccactgtggtggcaatcaggacctaaggtgaa gcaaacttgaagttctatctgacaagtttaggcagtaagagaaggagggaaatcggagcaaagctccctcactttattgt tgagaaactggcatctggaaagaagaaggaatttgcccaaagtcagtcagctgggataaaaacctgggtgtcctgtccag aaagtgcagggtgctttctgctctgtagcaaggcagcagacatctctgagccaggcccaccaacaggcccttatctggtg gttggatcatgatcccattttgcttggacatgctctcaggaagataaaaaccatggagaaacactaggccattgacaaat gatctgagacaactttagaaaacaatgtaggatgaatggaaagagaaagaaaggaaagaaaaaaaaaaaaaaaagg (SEQ ID NO: 12341) cagagccggcgcaggggaagcgcccggggccccgggtgcagcagcgcccgccgcctcccgggcctccccggcccgcagcc cggggtcccgggccccggggccggcacctctcgggctccggctccccgcgcgcaagatggctgacccggctgcggggccg ccgccgagcgagggcgaggagagcaccgtgcgcttcgcccgcaaaggcgccctccggcagaagaacgtgcatgaggtcaa gaaccacaaattcaccgcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttcggga agcagggattccagtgccaagtttgctgctttgtggtgcacaagcggtgccatgaatttgtcacattctcctgccctggc gctgacaagggtccagcctccgatgacccccgcagcaaacacaagtttaagatccacacgtactccagccccacgttttg tgaccactgtgggtcactgctgtatggactcatccaccaggggatgaaatgtgacacctgcatgatgaatgtgcacaagc gctgcgtgatgaatgttcccagcctgtgtggcacggaccacacggagcgccgcggccgcatctacatccaggcccacatc gacagggacgtcctcattgtcctcgtaagagatgctaaaaaccttgtacctatggaccccaatggcctgtcagatcccta cgtaaaactgaaactgattcccgatcccaaaagtgagagcaaacagaagaccaaaaccatcaaatgctccctcaaccctg agtggaatgagacatttagatttcagctgaaagaatcggacaaagacagaagactgtcagtagagatttgggattgggat ttgaccagcaggaatgacttcatgggatctttgtcctttgggatttctgaacttcagaaggccagtgttgatggctggtt taagttactgagccaggaggaaggcgagtacttcaatgtgcctgtgccaccagaaggaagtgaggccaatgaagaactgc ggcagaaatttgagagggccaagatcagtcagggaaccaaggtcccggaagaaaagacgaccaacactgtctccaaattt gacaacaatggcaacagagaccggatgaaactgaccgattttaacttcctaatggtgctggggaaaggcagctttggcaa ggtcatgctttcagaacgaaaaggcacagatgagctctatgctgtgaagatcctgaagaaggacgttgtgatccaagatg atgacgtggagtgcactatggtggagaagcgggtgttggccctgcctgggaagccgcccttcctgacccagctccactcc tgcttccagaccatggaccgcctgtactttgtgatggagtaσgtgaatgggggcgacctcatgtatcacatccagcaagt cggccggttcaaggagccccatgctgtattttacgctgcagaaattgccatcggtctgttcttcttacagagtaagggca tcatttaccgtgacctaaaacttgacaacgtgatgctcgattctgagggacacatcaagattgccgattttggcatgtgt aaggaaaacatctgggatggggtgacaaccaagacattctgtggcactccagactacatcgcccccgagataattgctta tcagccctatgggaagtccgtggattggtgggcatttggagtcctgctgtatgaaatgttggctgggcaggcaccctttg aaggggaggatgaagatgaactcttccaatccatcatggaacacaacgtagcctatcccaagtctatgtccaaggaagct gtggccatctgcaaagggctgatgaccaaacacccaggcaaacgtctgggttgtggacctgaaggcgaacgtgatatcaa agagcatgcatttttccggtatattgattgggagaaacttgaacgcaaagagatccagcccccttataagccaaaagcta gagacaagagagacacctccaacttcgacaaagagttcaccagacagcctgtggaactgacccccactgataaactcttc atcatgaacttggaccaaaatgaatttgctggcttctcttatactaacccagagtttgtcattaatgtgtaggtgaatgc aaactccatcgttgagcctggggtgtaagacttcaagccaagcgtatgtatcaattctagtcttccaggattcacggtgc acatgctggcattcaacatgtggaaagcttgtcttagaggcctttcttgtatgtgtagcttgctagtttgttttctacat ttgaaaatgtttagtttagaataagcgcattatccaattatagaggtacaattttccaaacttccagaaactcatcaaat gaacagacaatgtcaaaactactgtgtctgataccaaaatgcttcagtatttgtaatttttcaagtcagaagctgatgtt cctggtaaaagtttttacagttattctataatatcttctttgaatgctaagcatgagcgatatttttaaaaattgtgagt aagcttcggaattc (SEQ ID Nθ:12342) cagagccggcgcaggggaagcgcccggggccccgggtgcagcagcgcccgccgcctcccgggcctccccggcccgcagcc cggggtcccgggccccggggccggcacctctcgggctccggctccccgcgcgcaagatggctgacccggctgcggggccg ccgccgagcgagggcgaggagagcaccgtgcgcttcgcccgcaaaggcgccctccggcagaagaacgtgcatgaggtcaa gaaccacaaattcaccgcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttcggga agcagggattccagtgccaagtttgctgctttgtggtgcacaagcggtgccatgaatttgtcacattctcctgccctggc gctgacaagggtccagcctccgatgacccccgcagcaaacacaagtttaagatccacacgtactccagccccacgttttg tgaccactgtgggtcactgctgtatggactcatccaccaggggatgaaatgtgacacctgcatgatgaatgtgcacaagc gctgcgtgatgaatgttcccagcctgtgtggcacggaccacacggagcgccgcggccgcatctacatccaggcccacatc gacagggacgtcctcattgtcctcgtaagagatgctaaaaaccttgtacctatggaccccaatggcctgtcagatcccta cgtaaaactgaaactgattcccgatcccaaaagtgagagcaaacagaagaccaaaaccatcaaatgctccctcaaccctg agtggaatgagacatttagatttcagctgaaagaatcggacaaagacagaagactgtcagtagagatttgggattgggat ttgaccagcaggaatgacttcatgggatctttgtcctttgggatttctgaacttcagaaggccagtgttgatggctggtt taagttactgagccaggaggaaggcgagtacttcaatgtgcctgtgccaccagaaggaagtgaggccaatgaagaactgc ggcagaaatttgagagggccaagatcagtcagggaaccaaggtcccggaagaaaagacgaccaacactgtctccaaattt gacaacaatggcaacagagaccggatgaaactgaccgattttaacttcctaatggtgctggggaaaggcagctttggcaa ggtcatgctttcagaacgaaaaggcacagatgagctctatgctgtgaagatcctgaagaaggacgttgtgatccaagatg atgacgtggagtgcactatggtggagaagcgggtgttggccctgcctgggaagccgcccttcctgacccagctccactcc tgcttccagaccatggaccgcctgtactttgtgatggagtacgtgaatgggggcgacctcatgta cacatccagcaagt cggccggttcaaggagccccatgctgtattttacgctgcagaaattgccatcggtctgttcttcttacagagtaagggca tcatttaccgtgacctaaaacttgacaacgtgatgctcgattctgagggacacatcaagattgccgattttggcatgtgt aaggaaaacatctgggatggggtgacaaccaagacattctgtggcactccagactacatcgcccccgagataattgctta tcagccctatgggaagtccgtggattggtgggcatttggagtcctgctgtatgaaatgttggctgggcaggcaccctttg aaggggaggatgaagatgaactcttccaatccatcatggaacacaacgtagcctatcccaagtctatgtccaaggaagct gtggccatctgcaaagggctgatgaccaaacacccaggcaaacgtctgggttgtggacctgaaggcgaacgtgatatcaa agagcatgcatttttccggtatattgattgggagaaacttgaacgcaaagagatccagcccccttataagccaaaagctt gtgggcgaaatgctgaaaacttcgaccgatttttcacccgccatccaccagtcctaacacctcccgaccaggaagtcatc aggaatattgaccaatcagaattcgaaggattttcctttgttaactctgaatttttaaaacccgaagtcaagagctaagt agatgtgtagatctccgtccttcatttctgtcattcaagctcaacggctattgtggtgacatttttatgtttttcattgc caagttgcatccatgtttgattttctgatgagactagagtgacagtgtttcagaacccaaatgtcctcaggtagtttgga gcatctctatgagatgggattatgcagatggcctatggaaaatgcagctgcataattaacacattatcaaagtcctctta caatttattttccgcagcatgtcagctaagtagacccaatggggagagaaaatgcctgctttctttccctctttttctgc actgccatattcacccccaaccatccaatctgtggataattggatgttagcggtactcttccacttccggtcctggagct tggcttgtatccaagtgtatggttgctttgcctaagaggaatccctctatttcacctgttctggaggcaccagaccttga aaagaacatgctcaaaataaaatgttatctgttatttttgtaaactcaaagttaagatgatcaaagttctaaaattccaa gaatgtgcttttagacggtctcaatctaaaagcacttcaaggggtcaaagggcaaccagcttggtgctacctcagtgttg tagtttctgatactttatgtctttgctcaccctcatccccaaactacttgaaaagggcatttggcaccactctctgaaac aacacagtcactctagcaaggcccccaaagggccctggttttacattacatttcaaactttatttgctttggggttttgt ttctgttgttgttcaaatgcaaaaaaaagaaaaaaaaaagaaaaaaaaaggtgactcacattgttacacatgctttaaaa tatgtgttcaaatgttattaaccacaatgacgacctgttttgatttaaccaagaagacggctgcggagcctagcagactc aggcctgtgggaatgggatttgttacaaatctaggtttgttactggcttcagaaagctaattaagtgctctgaaaaagac accgtttcttgaaacaaagatggttgtattcctcactttgatgttgttttgcaagatgtttgtggaaatgttcatttgta tctggatctctgttatgtgccatttttcttctagcatcgag (SEQ ID NO: 12343) gtccttcattccttccacaactatttatccagcaccgtttctgggcacagggctccagcgatggtcccaacaggtacaat gacctctggggaccaagttcagttcttggtgagttctccagtgcctctcgatgtaggatgaaccgttggcatgctccact gacgctggctccttctgttgtttctcttggctccaggacccccgcagcaaacacaagtttaagatccacacgtactccag ccccacgttttgtgaccactgtgggtcactgctgtatggactcatccaccaggggatgaaatgtgacagtaagtactttc tctctctgggggcatctgctgatggcagaagcaatgggaagggctgcttccacttggtttggggtccaggtctgccatac attcccccctgtcctcgttggggctggtgtaccagttatctgttgctgcataatgatcctcccaccccaaaacactgtga ctgaagacaataaacatttttttagctcatgactctgcaaggcagtcctttgaatctgggctggcctcagctgatgtcac gcatgttcataaagcatgaactcatggttcatggtggattagcagatggaggtgggctggg (SEQ ID NO:12344) acatcaaggagacgagtcctggttggatagtaatgtctttaacacccctctagcatttattaatttcctctcttaacaaa taaaagatgcccttcagtcagatgcttaggacagatgacgcacctagagatattttaataatgtagatactcttgctgtt caaactcagaccaaaatgacgataggcttttttggcccccagagggtgcacaaatacgaccagaatttgtgaagacgagt cagaaatgaatgaaatttggaaaaatattgatctactgaaatccttcctccccacactattagccctatgttacagttgg ggaaacggagtcgttttgcagaggggatggacagaaggtagggagttctcttccaaacgtgcaggaggcaagcaaagcca agaatcttctctgtggtgagttagagacatataaaataaagatcgctcctcccctacctctgcagaacgtgtgtgtgtat gtgtgtgtaagtgtgtgcggccacaagcctttccgaatgagtgacagcgggagcccatccctccaggagacgcgtgcaga atgaccaatgggatggatgggggtggatgggtaccagtctccgcagaggccggggtgggaattcgctgcgccccacccct tccacccgctccccttcgccccgtaggtctttccactctcgctcctcccctgggcacatctcctgaacgcagccccgggg gccgaggacggggtggggtggggggcgaggctcgggtccgacgaccccgggctgcggtcccggcgctgcagagctgcggc tgtgcacgcttagccgcgaggcccgcggtagcccgggcgccgatatgtaaagcagctggcagcgctgggcggggcctggg cgcgactgcaaatgaggagggcgcgggctggcccgggggctccgcctccctcccccgcagctggggccagcggctgccaa gcgcactggtcgagcggcagcagctgggcgaggtgacagccccggctccgcgcgccggccgccagagccggcgcagggga agcgcccgcggccccgggtgcagcagcggccgccgcctcccgcgcctccccggcccgcagcccgcggtcccgcgccccgg ggccggcacctctcgggctccggctccccgcgcgcaagatggctgacccggctgcggggccgccgccgagcgagggcgag gagagcaccgtgcgcttcgcccgcaaaggcgccctcaggcagaagaacgtgcatgaggtcaagaaccacaaattcaccgc ccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggtgaccccccaggcactccggccccaggc cacgccgcgccaggaccccctctccgcgccctctgcgccctccgcaccctggaccccgcgtccccggactccccgctccg gaccctgctgcccgggactcccggatggacagtcctagccgttgccctgtccccaccctggtcccagacgggccgccgcg ggcgcctcctgccctctcctgctctcaggcgcctctaga (SEQ ID NO: 12345) gtcgactgcaggtcaacggacacatcaaggagagagtcctggttggatagtaatgtctttaacacccctctagcatttat taatttcctctcttaacaaataaaagatgacttcagttgaagatccttaggacagatgacggcacctggagatattttaa taatgtagataccctcttgctgttcaaactcagaccaaaagagatggctttttttcccccagagggtgcacaaatacgac agaatttgtgaagacgagtcagaaatgaatgaaatttggaaaaatattgatctactgaaatccttcctccccacactatt agccctatgttacagttggggaaacggagtcgttttgcagaggggatggacagaaggtagggagttctcttccaacgtgc aggaggcaagcaaagccaagcatcttctctgtggtggagttagagacatataaaataagatcgctcctcccctacctctg cagaacgtgtgtgtgtatgtgtgtgtaacgtgtgtgcggccacaagcctttccgaatgagtgacagcgggagcccatccc tccaggagacgcgtgcagaatgaccaatgggatggatgggggtggatgggtaccgtctccgcgaggccggggtggaattc gctgcgccccaccccttccacccgctccccttcgccccgtaggtctttccactctcgctcctcccctgggcacatctcct gaacgcagccccgggggccgaggacggggtggggtggggggcgaggctcgggtccgacgaccccgggctgcggtcccggc gctgcagagctgcggctgtgcacgcttagccgcgaggcccgcggtagcccgggcgccgatatgtaaagcagctggcagcg ctgggcggggcctgggcgcgatgcaaatgaggagggcggggctggcccggggctccgcctccctcccccgcagctggggc cagcggtgccaagcgcagctggacgagcggcagcagctgggcgagtgacagccccggctccgcgcgccgcggccgccaga gccggcgcaggggaagcgcccgcggccccgggtgcagcagcggccgccgcctcccgcgcctccccggcccgcagcccgcg gtcccgcggccccggggccggcacctctcgggctccggctccccgcgcgcaagatggctgacccggctgcggggccgccg ccgagcgagggcgaggagagcaccgtgcgcttcgcccgcaaaggcgccctcaggcagaagaacgtgcatgaggtcaagaa ccacaaattcaccgcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggtggagcgcgcgcg caaggcaccttcccgggcccccgaggcagcgccgcgccaagggaccccctctccgccctctgcgccctccgcaccctgga ccccgcgtccccggactccccgctccggaccctgctgccgggactcccggatggacagtcctgccgttgccctgtcccca ccctggtcccaggacgggggcgcctcctgccctctcctgctctcaggcgcctctagagcgcccaggggcagcgtcgcggg cgcctttgctccacctgactaggagcgcgcggggtctgtgcctgccctggagggcagcgcctcgggtgctctccgacccg gggttccctatctctccgcctgcttccgggcgcgaggagccctcgccccccaccccttgtttccggggggggggggcggc gccctgggtgtccttctctatctctgcgggcatgggacatcctttctcactcctctgtgcctcggcagcgccctgtgtta tctcccattgccctccccgagggcctggttcccctttccactcctcggtcacatcactgcgggcccctttcttccccagt ccctccagtagtggggcatcctttcctccttcccagtccccctcccagaggacaccaccgccgcggggtcactctcgccc tccctctgaatgcgtctttatctcttctcttttccgagggtgctcggggcatctatgggtacatctgtcgcctgccttca gcccctaccccgacggaaacgctccccactatcccgccacctggtggtcgcagcctcctctcttctgcaggagtgaaggc agatcggggttacagccgagctcccacctacccccacaaaggcggaagactcttgggcacccgcctgtggctgggagttt gcacctggggtacagaggcagggaggaaggcgggtgactctgtgggtaactagctggaggctgggcccccgggctgcctg acatacacctccttctgcttttgcaggggcttcgggaagcagggattccagtgccaaggtaggctctggggctttgggga tgctatttgtgggaagagagggtgaaaaatactttatagaagaagttactgagttaggcagagagtgaaagaatcacgtt ggtcggagtgacctcccaggctaggaattc (SEQ ID NO: 12346) aaagcgaccatgtatcctgagtggaagtcgacgttcgatgcccacatctatgaggggcgcgtcatccagattgtgctaat gcgggcagcagaggagccagtgtctgaggtgaccgtgggtgtgtcggtgctggccgagcgctgcaagaagaacaatggca aggctgagttctggctggacctgcagcctcaggccaaggtgttgatgtctgttcagtatttcctggaggacgtggattgc aaacagtctatgcgcagtgaggacgaggccaagttcccaacgatgaaccgccgcggagccatcaaacaggccaaaatcca ctacatcaagaaccatgagtttatcgccaccttctttgggcaacccaccttctgttctgtgtgcaaagactttgtctggg gcctcaacaagcaaggctacaaatgcaggcaatgtaacgctgccatccacaagaaatgcatcgacaagatcatcggcaga tgcactggcaccgcggccaacagccgggacactatattccagaaagaacgcttcaacatcgacatgccgcaccgcttcaa ggttcacaactacatgagccccaccttctgtgaccactgcggcagcctgctctggggactggtgaagcagggattaaagt gtgaagactgcggcatgaatgtgcaccataaatgccgggagaaggtggccaacctctgcggcatcaaccagaagcttttg gctgaggccttgaaccaagtcacccagagagcctcccggagatcagactcagcctcctcagagcctgttgggatatatca gggtttcgagaagaagaccggagttgctggggaggacatgcaagacaacagtgggacctacggcaagatctgggagggca gcagcaagtgcaacatcaacaaσttcatcttccacaaggtcctgggcaaaggcagcttcgggaaggtgctgcttggagag ctgaagggcagaggagagtactttgccatcaaggccctcaagaaggatgtggtcctgatcgacgacgacgtggagtgcac catggttgagaagcgggtgctgacacttgccgcagagaatccctttctcacccacctcatctgcaccttccagaccaagg accacctgttctttgtgatggagttcctcaacgggggggacctgatgtaccacatccaggacaaaggccgctttgaactc taccgtgccacgttttatgccgctgagataatgtgtggactgcagtttctacacagcaagggcatcatttacagggacct caaactggacaatgtgctgttggaccgggatggccacatcaagattgccgactttgggatgtgcaaagagaacatattcg gggagagccgggccagcaccttctgcggcacccctgactatatcgcccctgagatcctacagggcctgaagtacacattc tctgtggactggtggtctttcggggtccttctgtacgagatgctcattggccagtcccccttccatggtgatgatgagga tgaactcttcgagtccatccgtgtggacacgccacattatccccgctggatcaccaaggagtccaaggacatcctggaga agctctttgaaagggaaccaaccaagaggctgggagtgacgggaaacatcaaaatccaccccttcttcaagaccataaac tggactctgctggaaaagcggaggttggagccacccttcaggcccaaagtgaagtcacccagagactacagtaactttga ccaggagttcctgaacgagaaggcgcgcctctcctacagcgacaagaacctcatcgactccatggaccagtctgcattcg ctggcttctcctttgtgaaccccaaattcgagcacctcctggaagattgaggttcctggacagatcaggctagccctgcc ctccacccacacctgcccgctccccacgataagcaccagtgggactgtggtgacttctgctgctggccccgcccctgccc ccagagcgtccttggctgccgtctggccgggctctcatggtacttcctctgtgaactgtgtgtgaatctgcttttcctct gccttcggagggaaattgtaaatcctgtgtttcattacttgaatgtagttatctattgaaaatatactttagagcacaat gga (SEQ ID NO:12347) tgccgccgcgacccttggcgcctgcccctgcaacgggagccccactgcaggccccaccatggcgccgttcctgcgcatcg ccttcaactcctatgagctgggctccctgcaggccgaggacgaggcgaaccagcccttctgtgccgtgaagatgaaggag gcgctcagcacagagcgtgggaaaacactggtgcagaagaagccgaccatgtatcctgagtggaagtcgacgttcgatgc ccacatctatgaggggcgcgtcatccagattgtgctaatgcgggcagcagaggagccagtgtctgaggtgaccgtgggtg tgtcggtgctggccgagcgctgcaagaagaacaatggcaaggctgagttctggctggacctgcagcctcaggccaaggtg ttgatgtctgttcagtatttcctggaggacgtggattgcaaacaatctatgcgcagtgaggacgaggccaagttcccaac gatgaaccgccgcggagccatcaaacaggccaaaatccactacatcaagaaccatgagtttatcgccaccttctttgggc aacccaccttctgttctgtgtgcaaagactttgtctggggcctcaacaagcaaggctacaaatgcaggcaatgtaacgct gccatccacaagaaatgcatcgacaagatcatcggcagatgcactggcaccgcggccaacagccgggacactatattcca gaaagaacgcttcaacatcgacatgccgcaccgcttcaaggttcacaactacatgagccccaccttctgtgaccactgcg gcagcctgctctggggactggtgaagcagggattaaagtgtgaagactgcggcatgaatgtgcaccataaatgccgggag aaggtggccaacctctgcggcatcaaccagaagcttttggctgaggccttgaaccaagtcacccagagagcctcccggag atcagactcagcctcctcagagcctgttgggatatatcagggtttcgagaagaagaccggagttgctggggaggacatgc aagacaacagtgggacctacggcaagatctgggagggcagcagcaagtgcaacatcaacaacttcatcttccacaaggtc ctgggcaaaggcagcttcgggaaggtgctgcttggagagctgaagggcagaggagagtactctgccatcaaggccctcaa gaaggatgtggtcctgatcgacgacgacgtggagtgcaccatggttgagaagcgggtgctgacacttgccgcagagaatc cctttctcacccacctcatctgcaccttccagaccaaggaccacctgttctttgtgatggagttcctcaacgggggggac ctgatgtaccacatccaggacaaaggccgctttgaactctaccgtgccacgttttatgccgctgagataatgtgtggact gcagtttctacacagcaagggcatcatttacagggacctcaaactggacaatgtgctgttggaccgggatggccacatca agattgccgactttgggatgtgcaaagagaacatattcggggagagccgggccagcaccttctgcggcacccctgactat atcgcccctgagatcctacagggcctgaagtacacattctctgtggactggtggtctttcggggtccttctgtacgagat gctcattggccagtcccccttccatggtgatgatgaggatgaactcttcgagtccatccgtgtggacacgccacattatc cccgctggatcaccaaggagtccaaggacatcctggagaagctctttgaaagggaaccaaccaagaggctgggaatgacg ggaaacatcaaaatccaccccttcttcaagaccataaactggactctgctggaaaagcggaggttggagccacccttcag gcccaaagtgaagtcacccagagactacagtaactttgaccaggagttcctgaacgagaaggcgcgcctctcctacagcg acaagaacctcatcgactccatggaccagtctgcattcgctggcttctcctttgtgaaccccaaattcgagcacctcctg gaagattgaggttcctggacagat (SEQ ID NO:12348) cccaagatggaagggagcggcggccgcgtccgcctcaaggcgcattacgggggggacatcttcatcaccagcgtggacgc cgccacgaccttcgaggagctctgtgaggaagtgagagacatgtgtcgtctgcaccagcagcacccgctcaccctcaagt gggtggacagcgaaggtgacccttgcacggtgtcctcccagatggagctggaagaggctttccgcctggcccgtcagtgc agggatgaaggcctcatcattcatgttttcccgagcacccctgagcagcctggcctgccatgtccgggagaagacaaatc tatctaccgccggggagccagaagatggaggaagctgtaccgtgccaacggccacctcttccaagccaagcgctttaaca ggagagcgtactgcggtcagtgcagcgagaggatatggggcctcgcgaggcaaggctacaggtgcatcaactgcaaactg ctggtccataagcgctgccacggcctcgtcccgctgacctgcaggaagcatatggattctgtcatgccttcccaagagcc tccagtagacgacaagaacgaggacgccgaccttccttccgaggagacagatggaattgcttacatttcctcatcccgga agcatgacagcattaaagacgactcggaggaccttaagccagttatcgatgggatggatggaatcaaaatctctcagggg cttgggctgcaggactttgacctaatcagagtcatcgggcgcgggagctacgccaaggttctcctggtgcggttgaagaa gaatgaccaaatttacgccatgaaagtggtgaagaaagagctggtgcatgatgacgaggatattgactgggtacagacag agaagcacgtgtttgagcaggcatccagcaaccccttcctggtcggattacactcctgcttccagacgacaagtcggttg ttcctggtcattgagtacgtcaacggcggggacctgatgttccacatgcagaggcagaggaagctccctgaggagcacgc caggttctacgcggccgagatctgcatcgccctcaacttcctgcacgagagggggatcatctacagggacctgaagctgg acaacgtcctcctggatgcggacgggcacatcaagctcacagactacggcatgtgcaaggaaggcctgggccctggtgac acaacgagcactttctgcggaaccccgaattacatcgcccccgaaatcctgcggggagaggagtacgggttcagcgtgga ctggtgggcgctgggagtcctcatgtttgagatgatggccgggcgctccccgttcgacatcatcaccgacaacccggaca tgaacacagaggactaccttttccaagtgatcctggagaagcccatccggatcccccggttcctgtccgtcaaagcctcc catgttttaaaaggatttttaaataaggaccccaaagagaggctcggctgccggccacagactggattttctgacatcaa gtcccacgcgttcttccgcagcatagactgggacttgctggagaagaagcaggcgctccctccattccagccacagatca cagacgactacggtctggacaactttgacacacagttcaccagcgagcccgtgcagctgaccccagacgatgaggatgcc ataaagaggatcgaccagtcagagttcgaaggctttgagtata caacccattattgctgtccaccgaggagtcggtgtg aggccgcgtgcgtctctgtcgtggacacgcgtgattgaccctttaactgtatccttaaccaccgcatatgcatgccaggc tgggcacggctccgagggcggccagggacagacgcttgcgccgagaccgcagagggaagcgtcagcgggcgctgctggga gcagaacagtccctcacacctggcccggcaggcagcttcgtgctggaggaacttgctgctgtgcctgcgtcgcggcggat ccgcggggaccctgccgagggggctgtcatgcggtttccaaggtgcacattttccacggaaacagaactcgatgcactga cctgctccgccaggaaagtgagcgtgtagcgtcctgaggaataaaatgttccgatgaaaaaaaaaa (SEQ ID NO: 12349) gggccggcggcggcggcgactctggacgcgagccgggcccttcccgtggatcgccccagctgcggcgggcgtcgcggccg cccccgggtggcacttccgtgtgccgcggcgccggagcccgaggcggctgtagcccacatctcccgagcgacccccggcg cccgcccgccgcgcggaggcccgggccacacctcactggccgcttggcccatcccagtcagcgccgcgccgaaccccgtc cgcgcgcgccggggagcggcgcccccgccgctgccgccgcgacccttggcgcctgcccctgcaacgggagccccactgca ggccccaccatggcgccgttcctgcgcatcgccttcaactcctatgagctgggctccctgcaggccgaggacgaggcgaa ccagcccttctgtgccgtgaagatgaaggaggcgctcagcacagagcgtgggaaaacactggtgcagaagaagccgacca tgtatcctgagtggaagtcgacgttcgatgcccacatctatgaggggcgcgtcatccagattgtgctaatgcgggcagca gaggagccagtgtctgaggtgaccgtgggtgtgtcggtgctggccgagcgctgcaagaagaacaatggcaaggctgagtt ctggctggacctgcagcctcaggccaaggtgttgatgtctgttcagtatttcctggaggacgtggattgcaaacagtcta tgcgcagtgaggacgaggccaagttcccaacgatgaaccgccgcggagccatcaaacaggccaaaatccactacatcaag aaccatgagtttatcgccaccttctttgggcaacccaccttctgttctgtgtgcaaagactttgtctggggcctcaacaa gcaaggctacaaatgcaggcaatgtaacgctgccatccacaagaaatgcatcgacaagatcatcggcagatgcactggca ccgcggccaacagccgggacactatattccagaaagaacgcttcaacatcgacatgccgcaccgcttcaaggttcacaac tacatgagccccaccttctgtgaccactgcggcagcctgctctggggactggtgaagcagggattaaagtgtgaagactg cggcatgaatgtgcaccataaatgccgggagaaggtggccaacctctgcggcatcaaccagaagcttttggctgaggcct tgaaccaagtcacccagagagcctcccggagatcagactcagcctcctcagagcctgttgggatatatcagggtttcgag aagaagaccggagttgctggggaggacatgcaagacaacagtgggacctacggcaagatctgggagggcagcagcaagtg caacatcaacaacttcatcttccacaaggtcctgggcaaaggcagcttcgggaaggtgctgct (SEQ ID NO: 12350) ctccccgccccgaccatggtagtgttcaatggccttcttaagatcaaaatctgcgaggccgtgagcttgaagcccacagc ctggtcgctgcgccatgcggtgggaccccggccgcagactttccttctcgacccctacattgccctcaatgtggacgact cgcgcatcggccaaacggccaccaagcagaagaccaacagcccggcctggcacgacgagttcgtcaccgatgtgtgcaac ggacgcaagatcgagctggctgtctttcacgatgcccccataggctacgacgacttcgtggccaactgcaccatccagtt tgaggagctgctgcagaacgggagccgccacttcgaggactggattgatctggagccagaaggaagagtgtatgtgatca tcgatctctcagggtcgtcgggt^'gaagcccctaaagacaatgaagagcgtgtgttcagggaacgcatgcggccgaggaag cggcagggggccgtcaggcgcagggtccatcaggtcaacggccacaagttcatggccacctatcttcggcagcccaccta ctgctcccattgcagagacttcatctggggtgtcataggaaagcagggataccagtgtcaagtctgcacctgcgtggtcc acaagcggtgccacgagctcataatcacaaagtgtgctgggttaaagaagcaggagacccccgaccaggtgggctcccag cggttcagcgtcaacatgccccacaagttcggtatccacaactacaaggtccctaccttctgcgatcactgtgggtccct gctctggggactcttgcggcagggtttgcagtgtaaagtctgcaaaatgaatgttcaccgtcgatgtgagaccaacgtgg ctcccaactgtggagtggatgccagaggaatcgccaaagtactggccgacctgggcgttaccccagacaaaatcaccaac agcggccagagaaggaaaaagctcattgctggtgccgagtccccgcagcctgcttctggaagctcaccatctgaggaaga tcgatccaagtcagcacccacctccccttgtgaccaggaaataaaagaacttgagaacaacattcggaaagccttgtcat ttgacaaccgaggagaggagcaccgggcagcatcgtctcctgatggccagctgatgagccccggtgagaatggcgaagtc cggcaaggccaggccaagcgcctgggcctggatgagttcaacttcatcaaggtgttgggcaaaggcagctttggcaaggt catgttggcagaactcaagggcaaagatgaagtatatgctgtgaaggtcttaaagaaggacgtcatccttcaggatgatg acgtggactgcacaatgacagagaagaggattttggctctggcacggaaacacccgtaccttacccaactctactgctgc ttccagaccaaggaccgcctctttttcgtcatggaatatgtaaatggtggagacctcatgtttcagattcagcgctcccg aaaattcgacgagcctcgttcacggttctatgctgcagaggtcacatcggccctcatgttcctccatcagcatggagtca tctacagggatttgaaactggacaacatccttctggatgcagaaggtcactgcaagctggctgacttcgggatgtgcaag gaagggattctgaatggtgtgacgaccaccacgttctgtgggactcctgactacatagctcctgagatcctgcaggagtt ggagtatggcccctccgtggactggtgggccctgggggtgctgatgtacgagatgatggctggacagcctccctttgagg ccgacaatgaggacgacctatttgagtccatcctccatgacgacgtgctgtacccagtctggctcagcaaggaggctgtc agcatcttgaaagctttcatgacgaagaatccccacaagcgcctgggctgtgtggcatcgcagaatggcgaggacgccat caagcagcacccattcttcaaagagattgactgggtgctcctggagcagaagaagatcaagccacccttcaaaccacgca ttaaaaccaaaagagacgtcaataattttgaccaagactttacccgggaagagccggtactcacccttgtggacgaagca attgtaaagcagatcaaccaggaggaattcaaaggtttctcctactttggtgaagacctgatgccctgagagcccactgc agtt (SEQ ID NO: 12351) agccggcttctggaaactccctgtgtgagtgtgagggaatgagtatgaacaaggcacattatgtcttacttattgtatta gtttcctgttgctgctgtagcaagttaccaccaatttatggcttaaagcaattcaaattttttctcttgaattcttaaga tcagaagttctaaatgagtctaatggggctaaaatcaaggtgttaggcaaaggcagct (SEQ ID NO-.12352) tgcagctggagatccgggctcccacagcagatgagatccacgtaactgttggcgaggcccgtaacctaattcctatggac cccaatggtctctctgatccctatgtgaaactgaagctcatcccagaccctcggaacctgacgaaacagaagacccgaac ggtgaaagccacgctaaaccctgtgtggaatgagacctttgtgttcaacctgaagccaggggatgtggagcgccggctca gcgtggaggtgtgggactgggaccggacctcccgcaacgacttcatgggggccatgtcctttggcgtctcggagctgctc aaggcgcccgtggatggctggtacaagttactgaaccaggaggagggcgagtattacaatgtgccggtggccgatgctga caactgcagcctcctccagaagtttgaggcttgtaactaccccctggaattgtatgagcgggtgcggatgggcccctctt cctctcccatcccctccccttcccctagtcccaccgaccccaagcgctgcttcttcggggcgagtccaggacgcctgcac atctccgacttcagcttcctcatggttctaggaaaaggcagttttgggaaggtgatgctggccgagcgcaggggctctga tgagctctacgccatcaagatcttgaaaaaggacgtgatcgtccaggacgacgatgtggactgcacgctggtggagaaac gtgtgctggcgctggggggccggggtcctggcggccggccccacttcctcacccagctccactccaccttccagaccccg gaccgcctgtatttcgtgatggagtacgtcaccgggggagacttgatgtaccacattcaacagctgggcaagtttaagga gccccatgcagcgttctacgcggcagaaatcgctatcggcctcttcttccttcacaatcagggcatcatctacagggacc tgaagctggacaatgtgatgctggatgctgagggacacatcaagatcactgactttggcatgtgtaaggagaacgtcttc cccgggacgacaacccgcaccttctgcgggaccccggactacatagccccggagatcattgcctaccagccctatgggaa gtctgtcgattggtggtcctttggagttctgctgtatgagatgttggcaggacagcctcccttcgatggggaggacgagg aggagctgtttcaggccatcatggaacaaactgtcacctaccccaagtcgctttcccgggaagccgtggccatctgcaag gggttcctgaccaagcacccagggaagcgcctgggctcagggcctgatggggaacctaccatccgtgcacatggcttttt ccgctggattgactgggagcggctggaacgattggagatcccgcctcctttcagaccccgcccgtgtggccgcagcggcg agaactttgacaagttcttcacgcgggcggcgccagcgctgacccctccagaccgcctagtcctggccagcatcgaccag gccgatttccagggcttcacctacgtgaaccccgacttcgtgcacccggatgcccgcagccccaccagcccagtgcctgt gcccgtcatgtaatctcacccgccgccactaggtgtccccaacgtcccctccgccgtgccggcggcagccccacttcacc cccaacttcaccaccccctgtcccattctagatcctgcaccccagcattccagctctgcccccgcgggttctagacgccc ctcccaagcgttcctggccttctgaactccatacagcctctacagccgtcccgcgttcaagacttgagcg (SEQ ID NO: 12353) cggggtgtcttgggcccgggcggctgtagaggcggcggcgcctacgggcagtgggaggagccgcgcggttccggctgctc cggcgaggcgacccttgggtcggcgctgcgggcaggtggcaggtaggtggcggacggccgcggttctccggcaagcgcag gcggcggagtcccccacggcgcccgaagcgcccccccgcacccccggcctccagcgttgaggcgggggagtgaggagatg ccgacccagagggacagcagcaccatgtcccacacggtcgcaggcggcggcagcggggaccattcccaccaggtccgggt gaaagcctactaccgcggggatatcatgataacacattttgaaccttccatctcctttgagggcctttgcaatgaggttc gagacatgtgttcttttgacaacgaacagctcttcaccatgaaatggatagatgaggaaggagacccgtgtacagtatca tctcagttggagttagaagaagcctttagactttatgagctaaacaaggattctgaactcttgattcatgtgttcccttg tgtaccagaacgtcctgggatgccttgtccaggagaagataaatccatctaccgtagaggtgcacgccgctggagaaagc tttattgtgccaatggccacactttccaagccaagcgtttcaacaggcgtgctcactgtgccatctgcacagaccgaata tggggacttggacgccaaggatataagtgcatcaactgcaaactcttggttca aagaagtgccataaactcgtcacaat tgaatgtgggcggcattctttgccacaggaaccagtgatgcccatggatcagtcatccatgcattctgaccatgcacaga cagtaattccatataatccttcaagtcatgagagtttggatcaagttggtgaagaaaaagaggcaatgaacaccagggaa agtggcaaagcttcatccagtctaggtcttcaggattttgatttgctccgggtaataggaagaggaagttatgccaaagt actgttggttcgattaaaaaaaacagatcgtatttatgcaatgaaagttgtgaaaaaagagcttgttaatgatgatgagg a attgattgggtacagacagagaagcatgtgtttgagcaggcatccaatcatcctttccttgttgggctgcattcttgc tttcagacagaaagcagattgttctttgttatagagtatgtaaatggaggagacctaatgtttcatatgcagcgacaaag aaaacttcctgaagaacatgccagattttactctgcagaaatcagtctagcattaaattatcttcatgagcgagggataa tttatagagatttgaaactggacaatgtattactggactctgaaggccacattaaactcactgactacggcatgtgtaag gaaggattacggccaggagatacaaccagcactttctgtggtactcctaattacattgctcctgaaattttaagaggaga agattatggtttcagtgttgactggtgggctcttggagtgctcatgtttgagatgatggcaggaaggtctccatttgata ttgttgggagctccgataaccctgaccagaacacagaggattatctcttccaagttattttggaaaaacaaattcgcata ccacgttctctgtctgtaaaagctgcaagtgttctgaagagttttcttaataaggaccctaaggaacgattgggttgtca tcctcaaacaggatttgctgatattcagggacacccgttcttccgaaatgttgattgggatatgatggagcaaaaacagg tggtacctccctttaaaccaaatatttctggggaatttggtttggacaactttgattctcagtttactaatgaacctgtc cagctcactccagatgacgatgacattgtgaggaagattgatcagtctgaatttgaaggttttgagtatatcaatcctct tttgatgtctgcagaagaatgtgtctgatcctcatttttcaaccatgtattctactcatgttgccatttaatgcatggat aaacttgctgcaagcctggatacaattaaccattttatatttgccacctacaaaaaaacacccaatatcttctcttgtag actatatgaatcaattattacatctcgacccggaat (SEQ ID NO: 12354) gaattcggacggaggaggcagaatggccagtcgaggggcgcttaggcgtggcctttccccagggctgcctcgactcctgc acctgtcccgagggctggcctgagacgggactcccggttctcccgctgcgaagcaggccccccggggccggggcagcggc gccggcatgtcgtctggcaccatgaagttcaatggctatttgagggtccgcatcggtgaggcagtggggctgcagcccac ccgctggtccctgcgccactcgctcttcaagaagggccaccagctgctggacccctatctgacggtgagcgtggaccagg tgcgcgtgggccagaccagcaccaagcagaagaccaacaaacccacgtacaacgaggagttttgcgctaacgtcaccgac ggcggccacctcgagttggccgtcttccacgagacccccctgggctacgacttcgtggccaactgcaccctgcagttcca ggagctcgtcggcacgaccggcgcctcggacaccttcgagggttgggtggatctcgagccagaggggaaagtatttgtgg taataacccttaccgggagtttcactgaagctac ctccagagagaccggatcttcaaacattttaccaggaagcgccaa agggctatgcgaaggcgagtccaccagatcaatggacacaagttcatggccacgtatctgaggcagcccacctactgctc tcactgcagggagtttatctggggagtgtttgggaaacagggttatcagtgccaagtgtgcacctgtgtcgtccataaac gctgccatcatctaattgttacagcctgtacttgccaaaacaatattaacaaagtggattcaaagattgcagaacagagg ttcgggatcaacatcccacacaagttcagcatccacaactacaaagtgccaacattctgcgatcactgtggctcactgct ctggggaataatgcgacaaggacttcagtgtaaaatatgtaaaatgaatgtgcatattcgatgtcaagcgaacgtggccc ctaactgtggggtaaatgcggtggaacttgccaagaccctggcagggatgggtctccaacccggaaatatttctccaacc tcgaaactcgtttccagatcgaccctaagacgacagggaaaggagagcagcaaagaaggaaatgggattggggttaattc ttccaaccgacttggtatcgacaactttgagttcatccgagtgttggggaaggggagttttgggaaggtgatgcttgcaa gagtaaaagaaacaggagacctctatgctgtgaaggtgctgaagaaggacgtgattctgctggatgatgatgtggaatgc accatgaccgagaaaaggatcctgtctctggcccgcaatcaccccttcctcactcagttgttctgctgctttcagacccc cgatcgtctgttttttgtgatggagtttgtgaatgggggtgacttgatgttccacattcagaagtctcgtcgttttgatg aagcacgagctcgcttctatgctgcagaaatcatttcggctctcatgttcctccatgataaaggaatca ctatagagat ctgaaactggacaatgtcctgttggaccacgagggtcactgtaaactggcagacttcggaatgtgcaaggaggggatttg caatggtgtcaccacggccacattctgtggcacgccagactatatcgctccagagatcctccaggaaatgctgtacgggc ctgcagtagactggtgggcaatgggcgtgttgctctatgagatgctctgtggtcacgcgccttttgaggcagagaatgaa gatgacctctttgaggccatactgaatgatgaggtggtctaccctacctggctccatgaagatgccacagggatcctaaa atctttcatgaccaagaaccccaccatgcgcttgggcagcctgactcagggaggcgagcacgccatcttgagacatcctt tttttaaggaaatcgactgggcccagctgaaccatcgccaaatagaaccgcctttcagacccagaatcaaatcccgagaa gatgtcagtaattttgaccctgacttcataaaggaagagccagttttaactccaattgatgagggacatcttccaatgat taaccaggatgagtttagaaacttttcctatgtgtctccagaattgcaaccatagccttatggggagtgagagagagggc acgagaacccaaaggaatagagattctccaggaatttcctctatcggaccttcccagcatcagccttagaacaagaacct taccttcaaggagcaagtgaagaactctgtcgaaggatggaactttcagatatcaactatttagagtcc (SEQ ID NO:12355) gaattccttctctcctcctcctcgcccttctcctcgccctcctcctcctcctcgccctcccctcccgatcctcatcccct tgccctcccccagcccagggacttttccggaaagtttttattttccgtctgggctctcggagaaagaagctcctggctca gcggctgcaaaactttcctgctgccgcgccgccagcccccgccctccgctgcccggccctgcgccccgccgagcgatgag cgcccctccggtcctgcggccgcccagtccgctgctgcccgtggcggcggcagctgccgcagcggccgccgcactggtcc cagggtccgggcccgggcccgcgccgttcttggctcctgtcgcggccccggtcgggggcatctcgttccatctgcagatc ggcctgagccgtgagccggtgctgctgctgcaggactcgtccggggactacagcctggcgcacgtccgcgagatggcttg ctccattgtcgaccagaagttccctgaatgtggtttctacggaatgtatgataagatcctgctttttcgccatgacccta cctctgaaaacatccttcagctggtgaaagcggccagtgatatccaggaaggcgatcttattgaagtggtcttgtcacgt tccgccacctttgaagactttcagattcgtccccacgctctctttgttcattcatacagagctccagctttctgtgatca ctgtggagaaatgctgtgggggctggtacgtcaaggtcttaaatgtgaagggtgtggtctgaattaccataagagatgtg catttaaaatacccaacaattgcagcggtgtgaggcggagaaggctctcaaacgtttccctcactggggtcagcaccatc cgcacatcatctgctgaactctctacaagtgcccctgatgagccccttctgcaaaaatcaccatcagagtcgtttattgg tcgagagaagaggtcaaattctcaatcatacattggacgaccaattcaccttgacaagattttgatgtctaaagttaaag tgccgcacacatttgtcatccactcctacacccggcccacagtgtgccagtactgcaagaagcttctgaaggggcttttc aggcagggcttgcagtgcaaagattgcagattcaactgccataaacgttgtgcaccgaaagtaccaaacaactgccttgg cgaagtgaccattaatggagatttgcttagccctggggcagagtctgatgtggtcatggaagaagggagtgatgacaatg atagtgaaaggaacagtgggctcatggatgatatggaagaagcaatggtccaagatgcagagatggcaatggcagagtgc cagaacgacagtggcgagatgcaagatccagacccagaccacgaggacgccaacagaaccatcagtccatcaacaagcaa caatatcccactcatgagggtagtgcagtctgtcaaacacacgaagaggaaaagcagcacagtcatgaaagaaggatgga tggtccactacaccagcaaggacacgctgcggaaacggcactattggagattggatagcaaatgtattaccctctttcag aatgacacaggaagcaggtactacaaggaaattcctttatctgaaattttgtctctggaaccagtaaaaacttcagcttt aattcctaatggggccaatcctcattgtttcgaaatcactacggcaaatgtagtgtattatgtgggagaaaatgtggtca atccttccagcccatcaccaaataacagtgttctcaccagtggcgttggtgcagatgtggccaggatgtgggagatagcc atccagcatgcccttatgcccgtcattcccaagggctcctccgtgggtacaggaaccaacttgcacagagatatctctgt gagtatttcagtatcaaattgccagattcaagaaaatgtggacatcagcacagtatatcagatttttcctgatgaagtac tgggttctggacagtttggaattgtttatggaggaaaacatcgtaaaacaggaagagatgtagctattaaaatcattgac aaattacgatttccaacaaaacaagaaagccagcttcgtaatgaggttgcaattctacagaaccttcatcaccctggtgt tgtaaatttggagtgtatgtttgagacgcctgaaagagtgtttgttgttatggaaaaactccatggagacatgctggaaa tgatcttgtcaagtgaaaagggcaggttgccagagcacataacgaagtttttaattactcagatactcgtggctttgcgg caccttcattttaaaaatatcgttcactgtgacctcaaaccagaaaatgtgttgctagcctcagctgatccttttcctca ggtgaaactttgtgattttggttttgcccggatcattggagagaagtctttccggaggtcagtggtgggtacccccgctt acctggctcctgaggtcctaaggaacaagggctacaatcgctctctagacatgtggtctgttggggtcatcatctatgta agcctaagcggcacattcccatttaatgaagatgaagacatacacgaccaaattcagaatgcagctttcatgtatccacc aaatccctggaaggaaatatctcatgaagccattgatcttatcaacaatttgctgcaagtaaaaatgagaaagcgctaca gtgtggataagaccttgagccacccttggctacaggactatcagacctggttagatttgcgagagctggaatgcaaaatc ggggagcgctacatcacccatgaaagtgatgacctgaggtgggagaagtatgcaggcgagcagcggctgcagtaccccac acacctgatcaatccaagtgctagccacagtgacactcctgagactgaagaaacagaaatgaaagccctcggtgagcgtg tcagcatcctctgagttccatctcctataatctgtcaaaacactgtggaactaataaatacatacggtcaggtttaacat ttgccttgcagaactgccattattttctgtcagatgagaacaaagctgttaaactgttagcactgttgatgtatctgagt tgccaagacaaatcaacagaagcatttgtattttgtgtgaccaactgtgttgtattaacaaaagttccctgaaacacgaa acttgttattgtgaatgattcatgttatatttaatgcattaaacctgtctccactgtgcctttgcaaatcagtgtttttc ttactggagcttcattttggtaagagacagaatgtatctgtgaagtagttctgtttggtgtgtcccattggtgttgtcat tgtaaacaaactcttgaagagtcgattatttccagtgttctatgaacaactccaaaacccatgtgggaaaaaaatgaatg aggagggtagggaataaaatcctaagacacaaatgcatgaacaagttttaatgtatagttttgaatcctttgcctgcctg gtgtgcctcagtatatttaaactcaagacaatgcacctagctgtgcaagacctagtgctcttaagcctaaatgccttaga aatgtaaactgccatatataacagatacatttccctctttcttataatactctgttgtactatggaaaatcagctgctca gcaacctttcacctttgtgtatttttcaataataaaaaatattcttgtcaaaaaaaaaaaaa (SEQ ID NO: 12356) tgctcgctccagggcgcaaccatgtcgccatttcttcggattggcttgtccaactttgactgcgggtcctgccagtcttg tcagggcgaggctgttaacccttactgtgctgtgctcgtcaaagagtatgtcgaatcagagaacgggcagatgtatatcc agaaaaagcctaccatgtacccaccctgggacagcacttttgatgcccatatcaacaagggaagagtcatgcagatcatt gtgaaaggcaaaaacgtggacctcatctctgaaaccaccgtggagctctactcgctggctgagaggtgcaggaagaacaa cgggaagacagaaatatggttagagctgaaacctcaaggccgaatgctaatgaatgcaagatactttctggaaatgagtg acacaaaggacatgaatgaatttgagacggaaggcttctttgctttgcatcagcgccggggtgccatcaagcaggcaaag gtccaccacgtcaagtgccacgagttcactgccaccttcttcccacagcccacattttgctctgtctgccacgagtttgt ctggggcctgaacaaacagggctaccagtgccgacaatgcaatgcagcaattcacaagaagtgtattgataaagttatag caaagtgcacaggatcagctatcaatagccgagaaaccatgttccacaaggagagattcaaaattgacatgccacacaga tttaaagtctacaattacaagagcccgaccttctgtgaacactgtgggaccctgctgtggggactggcacggcaaggact caagtgtgatgcatgtggcatgaatgtgcatcatagatgccagacaaaggtggccaacctttgtggcataaaccagaagc taatggctgaagcgctggccatgattgagagcactcaacaggctcgctgcttaagagatactgaacagatcttcagagaa ggtccggttgaaattggtctcccatgctccatcaaaaatgaagcaaggccgccatgtttaccgacaccgggaaaaagaga gcctcagggcatttcctgggagtctccgttggatgaggtggataaaatgtgccatcttccagaacctgaactgaacaaag aaagaccatctctgcagattaaactaaaaattgaggattttatcttgcacaaaatgttggggaaaggaagttttggcaag gtcttcctggcagaattcaagaaaaccaatcaatttttcgcaataaaggccttaaagaaagatgtggtcttgatggacga tgatgttgagtgcacgatggtagagaagagagttctttccttggcctgggagcatccgtttctgacgcacatgttttgta cattccagaccaaggaaaacctcttttttgtgatggagtacctcaacggaggggacttaatgtaccacatccaaagctgc cacaagttcgacctttccagagcgacgttttatgctgctgaaatcattcttggtctgcagttccttcattccaaaggaat agtctacagggacctgaagctagataacatcctgttagacaaagatggacatatcaagatcgcggattttggaatgtgca aggagaacatgttaggagatgccaagacgaataccttctgtgggacacctgactacatcgccccagagatcttgctgggt cagaaatacaaccactctgtggactggtggtccttcggggttctcctttatgaaatgctgattggtcagtcgcctttcca cgggcaggatgaggaggagctcttccactccatccgcatggacaatcccttttacccacggtggctggagaaggaagcaa aggaccttctggtgaagctcttcgtgcgagaacctgagaagaggctgggcgtgaggggagacatccgccagcaccctttg tttcgggagatcaactgggaggaacttgaacggaaggagattgacccaccgttccggccgaaagtgaaatcaccatttga ctgcagcaatttcgacaaagaattcttaaacgagaagccccggctgtcatttgccgacagagcactgatcaacagcatgg accagaatatgttcaggaacttttccttcatgaaccccgggatggagcggctgatatcctgaatcttgcccctccagaga caggaaagaatttgccttctccctgggaactggttcaagagacactgcttgggttcctttttcaacttggaaaaagaaag aaacactcaacaataaagactgagacccgttcgcccccatgtgactttatctgtagcagaaaccaagtctacttcactaa tgacgatgccgtgtgtctcgtctcctgacatgtctcacagacgctcctgaagttaggtcattactaaccatagttattta cttgaaagatgggtctccgcacttggaaaggtttcaagacttgatactgcaataaattatggctcttcacctgggcgcca actgctgatcaacgaaatgcttgttgaatcaggggcaaacggagtacagacgtctcaagactgaaacggccccattgcct ggtctagtagcggatctcactcagccgcagacaagtaatcactaacccgttttattctatcctatctgtggatgtataaa tgctgggggccagccctggataggtttttatgggaattctttacaataaacatagcttgtacttg (SEQ ID NO: 12357) atgcccagcaggaccgaccccaagatggaagggagcggcggccgcgtccgcctcaaggcgcattacgggggggacatctt catcaccagcgtggacgccgccacgaccttcgaggagctctgtgaggaagtgagagacatgtgtcgtctgcaccagcagc acccgctcaccctcaagtgggtggacagcgaaggtgacccttgcacggtgtcctcccagatggagctggaagaggctttc cgcctggcccgtcagtgcagggatgaaggcctcatcattcatgttttcccgagcacccctgagcagcctggcctgccatg tccgggagaagacaaatctatctaccgccggggagccagaagatggaggaagctgtaccgtgccaacggccacctcttcc aagccaagcgctttaacaggagagcgtactgcggtcagtgcagcgagaggatatggggcctcgcgaggcaaggctacagg tgcatcaactgcaaactgctggtccataagcgctgccacggcctcgtcccgctgacctgcaggaagcatatggattctgt catgccttcccaagagcctccagtagacgacaagaacgaggacgccgaccttccttccgaggagacagatggaattgctt acatttcctcatcccggaagcatgacagcattaaagacgactcggaggaccttaagccagttatcgatgggatggatgga atcaaaatctctcaggggcttgggctgcaggactttgacctaatcagagtcatcgggcgcgggacgtacgccaaggttct cctggtgcggttgaagaagaatgaccaaatttacgccatgaaagtggtgaagaaagagctggtgcatgatgacgaggata ttgactgggtacagacagagaagcacgtgtttgagcaggcatccagcaaccccttcctggtcggattacactcctgcttc cagacgacaagtcggttgttcctggtcattgagtacgtcaacggcggggacctgatgttccacatgcagaggcagaggaa gctccctgaggagcacgccaggttctacgcggccgagatctgcatcgccctcaacttcctgcacgagagggggatcatct acagggacctgaagctggacaacgtcctcctggatgcggacggacacatcaagctcacagactacggcatgtgcaaggaa ggcctgggccctggtgacacaacgagcactttctgcggaaccccgaattacatcgcccccgaaatcctgcggggagagga gtacgggttcagcgtggactggtgggcgctgggagtcctcatgtttgagatgatggccgggcgctccccgttcgacatca tcaccgacaacccggacatgaacacagaggactaccttttccaagtgatcctggagaagcccatccggatcccccggttc ctgtccgtcaaagcctcccatgttttaaaaggatttttaaataaggaccccaaagagaggctcggctgccggccacagac tggattttctgacatcaagtcccacgcgttcttccgcagcatagactgggacttgctggagaagaagcaggcgctccctc cattccagccacagatcacagacgactacggtctggacaactttgacacacagttcaccagcgagcccgtgcagctgacc ccagacgatgaggatgccataaagaggatcgaccagtcagagttcgaaggctttgagtatatcaacccattattgctgtc caccgaggagtcggtgtga (SEQ ID NO: 12358) tgtcatgccttcccaagagcctccaggatggctgtcctccgacctcctccacctccaggctctagatggcaaagcccact tagcaaaagccacctgctctgtgatgatgggactggctcctgcctgtgggttcggaaagcccatcccaccctctacagcc tcttgctcctctgcaatgactgtgccttcacctgggggttccccagagactagtgagagtcatcgggcgtggaagctat (SEQ ID NO: 12359) ggagcaagaggtggttggggggggaccatggctgacgttttcccgggcaacgactccacggcgtctcaggacgtggccaa ccgcttcgcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaat eatcgcgcgcttet ea agcageccaccttctgcagccactgcaccgacttcatctgggggtttgggaaacaaggettccagtgccaagtttgctgt tttgtggtccacaagaggtgccatgaatttgttactttttcttgtccgggtgcggataagggacccgacactgatgaccc caggagcaagcacaagttcaaaatccacacttacggaagccccaccttctgcgatcactgtgggtcactgctctatggac ttatccatcaagggatgaaatgtgacacctgcgatatgaacgttcacaagcaatg^'cgtcatcaatgtccccagcctctgc ggaatggatcacactgagaagagggggcggatttacctaaaggctgaggttgctgatgaaaagctccatgtcacagtacg agatgcaaaaaatctaatccctatggatccaaacgggctttcagatccttatgtgaagctgaaacttattcctgatccca agaatgaaagcaagcaaaaaaccaaaaccatccgctccacactaaatccgcagtggaatgagtcctttacattcaaattg aaaccttcagacaaagaccgacgactgtctgtagaaatctgggactgggatcgaacaacaaggaatgacttcatgggatc cctttcctttggagtttcggagctgatgaagatgccggccagtggatggtacaagttgcttaaccaagaagaaggtgagt actacaacgtacccattccggaaggggacgaggaaggaaacatggaactcaggcagaaattcgagaaagccaaacttggc cctgctggcaacaaagtcatcagtccctctgaagacaggaaacaaccttccaacaaccttgaccgagtgaaactcacgga cttcaatttcctcatggtgttgggaaaggggagttttggaaaggtgatgcttgccgacaggaagggcacagaagaactgt atgcaatcaaaatcctgaagaaggatgtggtgattcaggatgatgacgtggagtgcaccatggtagaaaagcgagtcttg gccctgcttgacaaacccccgttcttgacgcagctgcactcctgcttccagacagtggatcggctgtacttcgtcatgga atatgtcaacggtggggacctcatgtaccacattcagcaagtaggaaaatttaaggaaccacaagcagtattctatgcgg cagagatttccatcggattgttctttcttcataaaagaggaatcatttatagggatctgaagttagataacgtcatgttg gattcagaaggacatatcaaaattgctgactttgggatgtgcaaggaacacatgatggatggagtcacgaccaggacctt ctgtgggactccagat atatcgccccagagataatcgcttatcagccgtatggaaaatctgtggactggtgggcctatg gcgtcctgttgtatgaaatgcttgccgggcagcctccatttgatggtgaagatgaagacgagctatttcagtctatcatg gagcacaacgtttcctatccaaaatccttgtccaaggaggctgtttctatctgcaaaggactgatgaccaaacacccagc caagcggctgggctgtgggcctgagggggagagggacgtgagagagcatgccttcttccggaggatcgactgggaaaaac tggagaacagggagatccagccaccattcaagcccaaagtgtgtggcaaaggagcagagaactttgacaagttcttcaca cgaggacagcccgtcttaacaccacctgatcagctggttattgctaacatagaccagtctgattttgaagggttctcgta tgtcaacccccagtttgtgcaccccatcttacagagtgcagtatgaaactcaccagcgagaacaaacacctccccagccc ccagccctccccgcagtggaagtgaatccttaaccctaaaattttaaggccacggcttgtgtctgattccatatggaggc ctgaaaattgtagggttattagtccaaatgtgatcaactgttcagggtctctctcttacaaccaagaacattatcttagt ggaagct atcacagttcaagtgatttccagaagttccagggcttctgagagaccatcaagggaactttaacaacttgac aaatgtccttgaagtaagatgcctcatctttagggaaaaatggggtttggatttctgcttaggcaaagtctcctgcagtt catccttctctgtcctcttcttgcttcaggcttggggaccgtccctgctgtccccactgtggtggcaatcaggacctaag gtgaagcaaacttgaagttctatctgacaagtttaggcagtaagagaaggagggaaatcggagcaaagctccctcacttt attgttgagaaactggcatctggaaagaagaaggaatttgcccaaagtcagtcagctgggataaaaacctgggtgtcctg tccagaaagtgcagggtgctttctgctctgtagcaaggcagcagacatctctgagccaggcccaccaacaggcccttatc tggtggttggatcatgatcccattttgcttggacatgctctcaggaagataaaaaccatggagaaacactaggccattga caaatgatctgagacaactttagaaaacaatgtaggatgaatggaaagagaaagaaaggaaagaaaaaaaaaaaaaaaag gcagagccggcgcaggggaagcgcccggggccccgggtgcagcagcgcccgccgcctcccgggcctccccggcccgcagc ccggggtcccgggccccggggccggcacctctcgggctccggctccccgcgcgcaagatggctgacccggctgcggggcc gccgccgagcgagggcgaggagagcaccgtgcgcttcgcccgcaaaggcgccctccggcagaagaacgtgcatgaggtca agaaccacaaattcaccgcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttcggg aagcagggattccagtgccaagtttgctgctttgtggtgcacaagcggtgccatgaatttgtcacattctcctgccctgg cgctgacaagggtccagcctccgatgacccccgcagcaaacacaagtttaagatccacacgtactccagccccacgtttt gtgaccactgtgggtcactgctgtatggactcatccaccaggggatgaaatgtgacacctgcatgatgaatgtgcacaag cgctgcgtgatgaatgttcccagcctgtgtggcacggaccacacggagcgccgcggccgcatctacatccaggcccacat cgacagggacgtcctcattgtcctcgtaagagatgctaaaaaccttgtacctatggaccccaatggcctgtcagatccct acgtaaaactgaaactgattcccgatcccaaaagtgagagcaaacagaagaccaaaaccatcaaatgctccctcaaccct gagtggaatgagacatttagatttcagctgaaagaatcggacaaagacagaagactgtcagtagagatttgggattggga tttgaccagcaggaatgacttcatgggatctttgtcctttgggatttctgaacttcagaaggccagtgttgatggctggt ttaagttactgagccaggaggaaggcgagtacttcaatgtgcctgtgccaccagaaggaagtgaggccaatgaagaactg cggcagaaatttgagagggccaagatcagtcagggaaccaaggtcccggaagaaaagacgaccaacactgtctccaaatt tgacaacaatggcaacagagaccggatgaaactgaccgattttaacttcctaatggtgctggggaaaggcagctttggca aggtcatgctttcagaacgaaaaggcacagatgagctctatgctgtgaagatcctgaagaaggacgttgtgatccaagat gatgacgtggagtgcactatggtggagaagcgggtgttggccctgcctgggaagccgcccttcctgacccagctccactc ctgcttccagaccatggaccgcctgtactttgtgatggagtacgtgaatgggggcgacctcatgtatcacatccagcaag tcggccggttcaaggagccccatgctgtattttacgctgcagaaattgccatcggtctgttcttcttacagagtaagggc atcatttaccgtgacctaaaacttgacaacgtgatgctcgattctgagggacacatcaagattgccgattttggcatgtg taaggaaaacatctgggatggggtgacaaccaagacattctgtggcactccagactacatcgcccccgagataattgctt atcagccctatgggaagtccgtggattggtgggcatttggagtcctgctgtatgaaatgttggctgggcaggcacccttt gaaggggaggatgaagatgaactcttccaatccatcatggaacacaacgtagcctatcccaagtctatgtccaaggaagc tgtggccatctgcaaagggctgatgaccaaacacccaggcaaacgtctgggttgtggacctgaaggcgaacgtgatatca aagagcatgcatttttccggtatattgattgggagaaacttgaacgcaaagagatccagcccccttataagccaaaagct agagacaagagagacacctccaacttcgacaaagagttcaccagacagcctgtggaactgacccccactgataaactctt catcatgaacttggaccaaaatgaatttgctggcttctcttatactaacccagagtttgtcattaatgtgtaggtgaatg caaactccatcgttgagcctggggtgtaagacttcaagccaagcgtatgtatcaattctagtcttccaggattcacggtg cacatgctggcattcaacatgtggaaagcttgtcttagaggcctttcttgtatgtgtagcttgctagtttgttttctaca tttgaaaatgtttagtttagaataagcgcattatccaattatagaggtacaattttccaaacttccagaaactcatcaaa tgaacagacaatgtcaaaactactgtgtctgataccaaaatgcttcagtatttgtaatttttcaagtcagaagctgatgt tcctggtaaaagtttttacagttattctataatatcttctttgaatgctaagcatgagcgatatttttaaaaattgtgag taagcttcggaattccagagccggcgcaggggaagcgcccggggccccgggtgcagcagcgcccgccgcctcccgggcct ccccggcccgcagcccggggtcccgggccccggggccggcacctctcgggctccggctccccgcgcgcaagatggctgac ccggctgcggggccgccgccgagcgagggcgaggagagcaccgtgcgcttcgcccgcaaaggcgccctccggcagaagaa cgtgcatgaggtcaagaaccacaaattcaccgcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttca tctggggcttcgggaagcagggattccagtgccaagtttgctgctttgtggtgcacaagcggtgccatgaatttgtcaca ttctcctgccctggcgctgacaagggtccagcctccgatgacccccgcagcaaacacaagtttaagatccacacgtactc cagccccacgttttgtgaccactgtgggtcactgctgtatggactcatccaccaggggatgaaatgtgacacctgcatga tgaatgtgcacaagcgctgcgtgatgaatgttcccagcctgtgtggcacggaccacacggagcgccgcggccgcatctac atccaggcccacatcgacagggacgtcctcattgtcctcgtaagagatgctaaaaaccttgtacctatggaccccaatgg cctgtcagatccctacgtaaaactgaaactgattcccgatcccaaaagtgagagcaaacagaagaccaaaaccatcaaat gctccctcaaccctgagtggaatgagacatttagatttcagctgaaagaatcggacaaagacagaagactgtcagtagag atttgggattgggatttgaccagcaggaatgacttcatgggatctttgtcctttgggatttctgaacttcagaaggccag tgttgatggctggtttaagttactgagccaggaggaaggcgagtacttcaatgtgcctgtgccaccagaaggaagtgagg ccaatgaagaactgcggcagaaatttgagagggccaagatcagtcagggaaccaaggtcccggaagaaaagacgaccaac actgtctccaaatttgacaacaatggcaacagagaccggatgaaactgaccgattttaacttcctaatggtgctggggaa aggcagctttggcaaggtcatgctttcagaacgaaaaggcacagatgagctctatgctgtgaagatcctgaagaaggacg ttgtgatccaagatgatgacgtggagtgcactatggtggagaagcgggtgttggccctgcctgggaagccgcccttcctg acccagctccactcctgcttccagaccatggaccgcctgtactttgtgatggagtacgtgaatgggggcgacctcatgta tcacatccagcaagtcggccggttcaaggagccccatgctgtattttacgctgcagaaattgccatcggtctgttcttct tacagagtaagggcatcatttaccgtgacctaaaacttgacaacgtgatgctcgattctgagggacacatcaagattgcc gattttggcatgtgtaaggaaaacatctgggatggggtgacaaccaagacattctgtggcactccagactacatcgcccc cgagataattgcttatcagccctatgggaagtccgtggattggtgggcatttggagtcctgctgtatgaaatgttggctg ggcaggcaccctttgaaggggaggatgaagatgaactcttccaatccatcatggaacacaacgtagcctatcccaagtct atgtccaaggaagctgtggccatctgcaaagggctgatgaccaaacacccaggcaaacgtctgggttgtggacctgaagg cgaacgtgatatcaaagagcatgcatttttccggtatattgattgggagaaacttgaacgcaaagagatccagccccctt ataagccaaaagcttgtgggcgaaatgctgaaaacttcgaccgatttttcacccgccatccaccagtcctaacacctccc gaccaggaagtcatcaggaatattgaccaatcagaattcgaaggattttcctttgttaactctgaatttttaaaacccg.a agtcaagagctaagtagatgtgtagatctccgtccttcatttctgtcattcaagctcaacggctattgtggtgacatttt tatgtttttcattgccaagttgcatccatgtttgattttctgatgagactagagtgacagtgtttcagaacccaaatgtc ctcaggtagtttggagcatctctatgagatgggattatgcagatggcctatggaaaatgcagctgcataattaacacatt atcaaagtcctcttacaatttattttccgcagcatgtcagctaagtagacccaatggggagagaaaatgcctgctttctt tccctctttttctgcactgccatattcacccccaaccatccaatctgtggataattggatgttagcggtactcttccact tccggtcctggagcttggcttgtatccaagtgtatggttgctttgcctaagaggaatccctctatttcacctgttctgga ggcaccagaccttgaaaagaacatgctcaaaataaaatgttatctgttatttttgtaaactcaaagttaagatgatcaaa gttctaaaattccaagaatgtgcttttagacggtctcaatctaaaagcacttcaaggggtcaaagggcaaccagcttggt gctacctcagtgttgtagtttctgatactttatgtctttgctcaccctcatccccaaactacttgaaaagggcatttggc accactctctgaaacaacacagtcactctagcaaggcccccaaagggccctggttttacattacatttcaaactttattt gctttggggttttgtttctgttgttgttcaaatgcaaaaaaaagaaaaaaaaaagaaaaaaaaaggtgactcacattgtt acacatgctttaaaatatgtgttcaaatgttattaaccacaatgacgacctgttttgatttaaccaagaagacggctgcg gagcctagcagactcaggcctgtgggaatgggatttgttacaaatctaggtttgttactggcttcagaaagctaattaag tgctctgaaaaagacaccgtttcttgaaacaaagatggttgtattcctcactttgatgttgttttgcaagatgtttgtgg aaatgttcatttgtatctggatctctgttatgtgccatttttcttctagcatcgaggtccttcattccttccacaactat ttatccagcaccgtttctgggcacagggctccagcgatggtcccaacaggtacaatgacctctggggaccaagttcagtt cttggtgagttctccagtgcctctcgatgtaggatgaaccgttggcatgctccactgacgctggctccttctgttgtttc tcttggctccaggacccccgcagcaaacacaagtttaagatccacacgtactccagccccacgttttgtgaccactgtgg gtcactgctgtatggactcatccaccaggggatgaaatgtgacagtaagtactttctctctctgggggcatctgctgatg gcagaagcaatgggaagggctgcttccacttggtttggggtccaggtctgccatacattcccccctgtcctcgttggggc tggtgtaccagttatctgttgctgcataatgatcctcccaccccaaaacactgtgactgaagacaataaacattttttta gctcatgactctgcaaggcagtcctttgaatctgggctggcctcagctgatgtcacgcatgttcataaagcatgaactca tggttcatggtggattagcagatggaggtgggctgggacatcaaggagacgagtcctggttggatagtaatgtctttaac acccctctagcatttattaatttcctctcttaacaaataaaagatgcccttcagtcagatgcttaggacagatgacgcac ctagagatattttaataatgtagatactcttgctgttcaaactcagaccaaaatgacgataggcttttttggcccccaga gggtgcacaaatacgaccagaatttgtgaagacgagtcagaaatgaatgaaatttggaaaaatattgatctactgaaatc cttcctccccacactattagccctatgttacagttggggaaacggagtcgttttgcagaggggatggacagaaggtaggg agttctcttccaaacgtgcaggaggcaagcaaagccaagaatcttctctgtggtgagttagagacatataaaataaagat cgctcctcccctacctctgcagaacgtgtgtgtgtatgtgtgtgtaagtgtgtgcggccacaagcctttccgaatgagtg acagcgggagcccatccctccaggagacgcgtgcagaatgaccaatgggatggatgggggtggatgggtaccagtctccg cagaggccggggtgggaattcgctgcgccccaccccttccacccgctccccttcgccccgtaggtctttccactctcgct cctcccctgggcacatctcctgaacgcagccccgggggccgaggacggggtggggtggggggcgaggctcgggtccgacg accccgggctgcggtcccggcgctgcagagctgcggctgtgcacgcttagccgcgaggcccgcggtagcccgggcgccga tatgtaaagcagctggcagcgctgggcggggcctgggcgcgactgcaaatgaggagggcgcgggctggcccgggggctcc gcctccctcccccgcagctggggccagcggctgccaagcgcactggtcgagcggcagcagctgggcgaggtgacagcccc ggctccgcgcgccggccgccagagccggcgcaggggaagcgcccgcggccccgggtgcagcagcggccgccgcctcccgc gcctccccggcccgcagcccgcggtcccgcgccccggggccggcacctctcgggctccggctccccgcgcgcaagatggc tgacccggctgcggggccgccgccgagcgagggcgaggagagcaccgtgcgcttcgcccgcaaaggcgccctcaggcaga agaacgtgcatgaggtcaagaaccacaaattcaccgcccgcttcttcaagcagcccaccttctgcagccactgcaccgac ttcatctggtgaccccccaggcactccggccccaggccacgccgcgccaggaccccctctccgcgccctctgcgccctcc gcaccctggaccccgcgtccccggactccccgctccggaccctgctgcccgggactcccggatggacagtcctagccgtt gccctgtccccaccctggtcccagacgggccgccgcgggcgcctcctgccctctcctgctctcaggcgcctctagagtcg actgcaggtcaacggacacatcaaggagagagtcctggttggatagtaatgtctttaacacccctctagcatttattaat ttcctctcttaacaaataaaagatgacttcagttgaagatccttaggacagatgacggcacctggagatattttaataat gtagataccctcttgctgttcaaactcagaccaaaagagatggctttttttcccccagagggtgcacaaatacgacagaa tttgtgaagacgagtcagaaatgaatgaaatttggaaaaatattgatctactgaaatccttcctccccacactattagcc ctatgttacagttggggaaacggagtcgttttgcagaggggatggacagaaggtagggagttctcttccaacgtgcagga ggcaagcaaagccaagcatcttctctgtggtggagttagagacatataaaataagatcgctcctcccctacctctgcaga acgtgtgtgtgtatgtgtgtgtaacgtgtgtgcggccacaagcctttccgaatgagtgacagcgggagcccatccctcca ggagacgcgtgcagaatgaccaatgggatggatgggggtggatgggtaccgtctccgcgaggccggggtggaattcgctg cgccccaccccttccacccgctccccttcgccccgtaggtctttccactctcgctcctcccctgggcacatctcctgaac gcagccccgggggccgaggacggggtggggtggggggcgaggctcgggtccgacgaccccgggctgcggtcccggcgctg cagagctgcggctgtgcacgcttagccgcgaggcccgcggtagcccgggcgccgatatgtaaagcagctggcagcgctgg gcggggcctgggcgcgatgcaaatgaggagggcggggctggcccggggctccgcctccctcccccgcagctggggccagc ggtgccaagcgcagctggacgagcggcagcagctgggcgagtgacagccccggctccgcgcgccgcggccgccagagccg gcgcaggggaagcgcccgcggccccgggtgcagcagcggccgccgcctcccgcgcctccccggcccgcagcccgcggtcc cgcggccccggggccggcacctctcgggctccggctccccgcgcgcaagatggctgacccggctgcggggccgccgccga gcgagggcgaggagagcaccgtgcgcttcgcccgcaaaggcgccctcaggcagaagaacgtgcatgaggtcaagaaccac aaattcaccgcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggtggagcgcgcgcgcaag gcaccttcccgggcccccgaggcagcgccgcgccaagggaccccctctccgccctctgcgccctccgcaccctggacccc gcgtccccggactccccgctccggaccctgctgccgggactcccggatggacagtcctgccgttgccctgtccccaccct ggtcccaggacgggggcgcctcctgccctctcctgctctcaggcgcctctagagcgcccaggggcagcgtcgcgggcgcc tttgctccacctgactaggagcgcgcggggtctgtgcctgccctggagggcagcgcctcgggtgctctccgacccggggt tccctatctctccgcctgcttccgggcgcgaggagccctcgccccccaccccttgtttccggggggggggggcggcgccc tgggtgtccttctctatctctgcgggcatgggacatcctttctcactcctctgtgcctcggcagcgccctgtg tatctc ccattgccctccccgagggcctggttcccctttccactcctcggtcacatcactgcgggcccctttcttccccagtccct ccagtagtggggcatcctttcctccttcccagtccccctcccagaggacaccaccgccgcggggtcactctcgccctccc tctgaatgcgtctttatctcttctcttttccgagggtgctcggggcatctatgggtacatctgtcgcctgccttcagccc ctaccccgacggaaacgctccccactatcccgccacctggtggtcgcagcctcctctcttctgcaggagtgaaggcagat cggggttacagccgagctcccacctacccccacaaaggcggaagactcttgggcacccgcctgtggctgggagtttgcac ctggggtacagaggcagggaggaaggcgggtgactctgtgggtaactagctggaggctgggcccccgggctgcctgacat acacctccttctgcttttgcaggggcttcgggaagcagggattccagtgccaaggtaggctctggggctttggggatgct atttgtgggaagagagggtgaaaaatactttatagaagaagttactgagttaggcagagagtgaaagaatcacgttggtc ggagtgacctcccaggctaggaattcaaagcgaccatgtatcctgagtggaagtcgacgttcgatgcccacatctatgag gggcgcgtcatccagattgtgctaatgcgggcagcagaggagccagtgtctgaggtgaccgtgggtgtgtcggtgctggc cgagcgctgcaagaagaacaatggcaaggctgagttctggctggacctgcagcctcaggccaaggtgttgatgtctgttc agtatttcctggaggacgtggattgcaaacagtctatgcgcagtgaggacgaggccaagttcccaacgatgaaccgccgc ggagccatcaaacaggccaaaatccactacatcaagaaccatgagtttatcgccaccttctttgggcaacccaccttctg ttctgtgtgcaaagactttgtctggggcctcaacaagcaaggctacaaatgcaggcaatgtaacgctgccatccacaaga aatgcatcgacaagatcatcggcagatgcactggcaccgcggccaacagccgggacactatattccagaaagaacgcttc aacatcgacatgccgcaccgcttcaaggttcacaactacatgagccccaccttctgtgaccactgcggcagcctgctctg gggactggtgaagcagggattaaagtgtgaagactgcggcatgaatgtgcaccataaatgccgggagaaggtggccaacc tctgcggcatcaaccagaagcttttggctgaggccttgaaccaagtcacccagagagcctcccggagatcagactcagcc tcctcagagcctgttgggatatatcagggtttcgagaagaagaccggagttgctggggaggacatgcaagacaacagtgg gacctacggcaagatctgggagggcagcagcaagtgcaacatcaacaacttcatcttccacaaggtcctgggcaaaggca gcttcgggaaggtgctgcttggagagctgaagggcagaggagagtactttgccatcaaggccctcaagaaggatgtggtc ctgatcgacgacgacgtggagtgcaccatggttgagaagcgggtgctgacacttgccgcagagaatccctttctcaccca cctcatctgcaccttccagaccaaggaccacctgttctttgtgatggagttcctcaacgggggggacctgatgtaccaca tccaggacaaaggccgctttgaactctaccgtgccacgttttatgccgctgagataatgtgtggactgcagtttctacac agcaagggcatcatttacagggacctcaaactggacaatgtgctgttggaccgggatggccacatcaagattgccgactt tgggatgtgcaaagagaacatattcggggagagccgggccagcaccttctgcggcacccctgactatatcgcccctgaga tcctacagggcctgaagtacacattctctgtggactggtggtctttcggggtccttctgtacgagatgctcattggccag tcccccttccatggtgatgatgaggatgaactcttcgagtccatccgtgtggacacgccacattatccccgctggatcac caaggagtccaaggacatcctggagaagctctttgaaagggaaccaaccaagaggctgggagtgacgggaaacatcaaaa tccaccccttcttcaagaccataaactggactctgctggaaaagcggaggttggagccacccttcaggcccaaagtgaag tcacccagagactacagtaactttgaccaggagttcctgaacgagaaggcgcgcctctcctacagcgacaagaacctcat cgactccatggaccagtctgcattcgctggcttctcctttgtgaaccccaaattcgagcacctcctggaagattgaggtt cctggacagatcaggctagccctgccctccacccacacctgcccgctccccacgataagcaccagtgggactgtggtgac ttctgctgctggccccgcccctgcccccagagcgtccttggctgccgtctggccgggctctcatggtacttcctctgtga actgtgtgtgaatctgcttttcctctgccttcggagggaaattgtaaatcctgtgtttcattacttgaatgtagttatct attgaaaatatactttagagcacaatggatgccgccgcgacccttggcgcctgcccctgcaacgggagccccactgcagg ccccaccatggcgccgttcctgcgcatcgccttcaactcctatgagctgggctccctgcaggccgaggacgaggcgaacc agcccttctgtgccgtgaagatgaaggaggcgctcagcacagagcgtgggaaaacactggtgcagaagaagccgaccatg tatcctgagtggaagtcgacgttcgatgcccacatctatgaggggcgcgtcatccagattgtgctaatgcgggcagcaga ggagccagtgtctgaggtgaccgtgggtgtgtcggtgctggccgagcgctgcaagaagaacaatggcaaggctgagttct ggctggacctgcagcctcaggccaaggtgttgatgtctgttcagtatttcctggaggacgtggattgcaaacaatctatg cgcagtgaggacgaggccaagttcccaacgatgaaccgccgcggagccatcaaacaggccaaaatccactacatcaagaa ccatgagtttatcgccaccttctttgggcaacccaccttctgttctgtgtgcaaagactttgtctggggcctcaacaagc aaggctacaaatgcaggcaatgtaacgctgccatccacaagaaatgcatcgacaagatcatcggcagatgcactggcacc gcggccaacagccgggacactatattccagaaagaacgcttcaacatcgacatgccgcaccgcttcaaggttcacaacta catgagccccaccttctgtgaccactgcggcagcctgctctggggactggtgaagcagggattaaagtgtgaagactgcg gcatgaatgtgcaccataaatgccgggagaaggtggccaacctctgcggcatcaaccagaagcttttggctgaggccttg aaccaagtcacccagagagcctcccggagatcagactcagcctcctcagagcctgttgggatatatcagggtttcgagaa gaagaccggagttgctggggaggacatgcaagacaacagtgggacctacggcaagatctgggagggcagcagcaagtgca acatcaacaacttcatcttccacaaggtcctgggcaaaggcagcttcgggaaggtgctgcttggagagctgaagggcaga ggagagtactctgccatcaaggccctcaagaaggatgtggtcctgatcgacgacgacgtggagtgcaccatggttgagaa gcgggtgctgacacttgccgcagagaatccctttctcacccacctcatctgcaccttccagaccaaggaccacctgttct ttgtgatggagttcctcaacgggggggacctgatgtaccacatccaggacaaaggccgctttgaactctaccgtgccacg ttttatgccgctgagataatgtgtggactgcagtttctacacagcaagggcatcatttacagggacctcaaactggacaa tgtgctgttggaccgggatggccacatcaagattgccgactttgggatgtgcaaagagaacatattcggggagagccggg ccagcaccttctgcggcacccctgactatatcgcccctgagatcctacagggcctgaagtacacattctctgtggactgg tggtctttcggggtccttctgtacgagatgctcattggccagtcccccttccatggtgatgatgaggatgaactcttcga gtccatccgtgtggacacgccacattatccccgctggatcaccaaggagtccaaggacatcctggagaagctctttgaaa gggaaccaaccaagaggctgggaatgacgggaaacatcaaaatccaccccttcttcaagaccataaactggactctgctg gaaaagcggaggttggagccacccttcaggcccaaagtgaagtcacccagagactacagtaactttgaccaggagttcct gaacgagaaggcgcgcctctcctacagcgacaagaacctcatcgactccatggaccagtctgcattcgctggcttctcct ttgtgaaccccaaattcgagcacctcctggaagattgaggttcctggacagatcccaagatggaagggagcggcggccgc gtccgcctcaaggcgcattacgggggggacatcttcatcaccagcgtggacgccgccacgaccttcgaggagctctgtga ggaagtgagagacatgtgtcgtctgcaccagcagcacccgctcaccctcaagtgggtggacagcgaaggtgacccttgca cggtgtcctcccagatggagctggaagaggctttccgcctggcccgtcagtgcagggatgaaggcctcatcattcatgtt ttcccgagcacccctgagcagcctggcctgccatgtccgggagaagacaaatctatctaccgccggggagccagaagatg gaggaagctgtaccgtgccaacggccacctcttccaagccaagcgctttaacaggagagcgtactgcggtcagtgcagcg agaggatatggggcctcgcgaggcaaggctacaggtgcatcaactgcaaactgctggtccataagcgctgccacggcctc gtcccgctgacctgcaggaagcatatggattctgtcatgccttcccaagagcctccagtagacgacaagaacgaggacgc cgaccttccttccgaggagacagatggaattgcttacatttcctcatcccggaagcatgacagcattaaagacgactcgg aggaccttaagccagttatcgatgggatggatggaatcaaaatctctcaggggcttgggctgcaggactttgacctaatc agagtcatcgggcgcgggagctacgccaaggttctcctggtgcggttgaagaagaatgaccaaatttacgccatgaaagt ggtgaagaaagagctggtgcatgatgacgaggatattgactgggtacagacagagaagcacgtgtttgagcaggcatcca gcaaccccttcctggtcggattacactcctgcttccagacgacaagtcggttgttcctggtcattgagtacgtcaacggc ggggacctgatgttccacatgcagaggcagaggaagctccctgaggagcacgccaggttctacgcggccgagatctgcat cgccctcaacttcctgcacgagagggggatcatctacagggacctgaagctggacaacgtcctcctggatgcggacgggc acatcaagctcacagactacggcatgtgcaaggaaggcctgggccctggtgacacaacgagcactttctgcggaaccccg aattacatcgcccccgaaatcctgcggggagaggagtacgggttcagcgtggactggtgggcgctgggagtcctcatgtt tgagatgatggccgggcgctccccgttcgacatcatcaccgacaacccggacatgaacacagaggactaccttttccaag tgatcctggagaagcccatccggatcccccggttcctgtccgtcaaagcctcccatgttttaaaaggatttttaaataag gaccccaaagagaggctcggctgccggccacagactggattttctgacatcaagtcccacgcgttcttccgcagcataga ctgggacttgctggagaagaagcaggcgctccctccattccagccacagatcacagacgactacggtctggacaactttg acacacagttcaccagcgagcccgtgcagctgaccccagacgatgaggatgccataaagaggatcgaccagtcagagttc gaaggctttgagtatatcaacccattattgctgtccaccgaggagtcggtgtgaggccgcgtgcgtctctgtcgtggaca cgcgtgattgaccctttaactgtatccttaaccaccgcatatgcatgccaggctgggcacggctccgagggcggccaggg acagacgcttgcgccgagaccgcagagggaagcgtcagcgggcgctgctgggagcagaacagtccctcacacctggcccg gcaggcagcttcgtgctggaggaacttgctgctgtgcctgcgtcgcggcggatccgcggggaccctgccgagggggctgt catgcggtttccaaggtgcacattttccacggaaacagaactcgatgcactgacctgctccgccaggaaagtgagcgtgt agcgtcctgaggaataaaatgttccgatgaaaaaaaaaagggccggcggcggcggcgactctggacgcgagccgggccct tcccgtggatcgccccagctgcggcgggcgtcgcggccgcccccgggtggcacttccgtgtgccgcggcgccggagcccg aggcggctgtagcccacatctcccgagcgacccccggcgcccgcccgccgcgcggaggcccgggccacacctcactggcc gcttggcccatcccagtcagcgccgcgccgaaccccgtccgcgcgcgccggggagcggcgcccccgccgctgccgccgcg acccttggcgcctgcccctgcaacgggagccccactgcaggccccaccatggcgccgttcctgcgcatcgccttcaactc ctatgagctgggctccctgcaggccgaggacgaggcgaaccagcccttctgtgccgtgaagatgaaggaggcgctcagca cagagcgtgggaaaacactggtgcagaagaagccgaccatgtatcctgagtggaagtcgacgttcgatgcccacatctat gaggggcgcgtcatccagattgtgctaatgcgggcagcagaggagccagtgtctgaggtgaccgtgggtgtgtcggtgct ggccgagcgctgcaagaagaacaatggcaaggctgagttctggctggacctgcagcctcaggccaaggtgttgatgtctg ttcagtatttcctggaggacgtggattgcaaacagtctatgcgcagtgaggacgaggccaagttcccaacgatgaaccgc cgcggagccatcaaacaggccaaaatccactacatcaagaaccatgagtttatcgccaccttctttgggcaacccacctt ctgttctgtgtgcaaagactttgtctggggcctcaacaagcaaggctacaaatgcaggcaatgtaacgctgccatccaca agaaatgcatcgacaagatcatcggcagatgcactggcaccgcggccaacagccgggacactatattccagaaagaacgc ttcaacatcgacatgccgcaccgcttcaaggttcacaactacatgagccccaccttctgtgaccactgcggcagcctgct ctggggactggtgaagcagggattaaagtgtgaagactgcggcatgaatgtgcaccataaatgccgggagaaggtggcca acctctgcggcatcaaccagaagcttttggctgaggccttgaaccaagtcacccagagagcctcccggagatcagactca gcctcctcagagcctgttgggatatatcagggtttcgagaagaagaccggagttgctggggaggacatgcaagacaacag tgggacctacggcaagatctgggagggcagcagcaagtgcaacatcaacaacttcatcttccacaaggtcctgggcaaag gcagcttcgggaaggtgctgctctccccgccccgaccatggtagtgttcaatggccttcttaagatcaaaatctgcgagg ccgtgagcttgaagcccacagcctggtcgctgcgccatgcggtgggaccccggccgcagactttccttctcgacccctac attgccctcaatgtggacgactcgcgcatcggccaaacggccaccaagcagaagaccaacagcccggcctggcacgacga gttcgtcaccgatgtgtgcaacggacgcaagatcgagctggctgtctttcacgatgcccccataggctacgacgacttcg tggccaactgcaccatccagtttgaggagctgctgcagaacgggagccgccacttcgaggactggattgatctggagcca gaaggaagagtgtatgtgatcatcgatctctcagggtcgtcgggtgaagcccctaaagacaatgaagagcgtgtgttcag ggaacgcatgcggccgaggaagcggcagggggccgtcaggcgcagggtccatcaggtcaacggccacaagttcatggcca cctatcttcggcagcccacctactgctcccattgcagagacttcatctggggtg cataggaaagcagggataccagtgt caagtctgcacctgcgtggtccacaagcggtgccacgagctcataatcacaaagtgtgctgggttaaagaagcaggagac ccccgaccaggtgggctcccagcggttcagcgtcaacatgccccacaagttcggtatccacaactacaaggtccctacct tctgcgatcactgtgggtccctgctctggggactcttgcggcagggtttgcagtgtaaagtctgcaaaatgaatgttcac cgtcgatgtgagaccaacgtggctcccaactgtggagtggatgccagaggaatcgccaaagtactggccgacctgggcgt taccccagacaaaatcaccaacagcggccagagaaggaaaaagctcat gctggtgccgagtccccgcagcctgcttctg gaagctcaccatctgaggaagatcgatccaagtcagcacccacctccccttgtgaccaggaaataaaagaacttgagaac aacattcggaaagccttgtcatttgacaaccgaggagaggagcaccgggcagcatcgtctcctgatggccagctgatgag ccccggtgagaatggcgaagtccggcaaggccaggccaagcgcctgggcctggatgagttcaacttcatcaaggtgttgg gcaaaggcagctttggcaaggtcatgttggcagaactcaagggcaaagatgaagtatatgctgtgaaggtcttaaagaag gacgtcatccttcaggatgatgacgtggactgcacaatgacagagaagaggattttggctctggcacggaaacacccgta ccttacccaactctactgctgcttccagaccaaggaccgcctctttttcgtcatggaatatgtaaatggtggagacctca tgtttcagattcagcgctcccgaaaattcgacgagcctcgttcacggttctatgctgcagaggtcacatcggccctcatg ttcctccatcagcatggagtcatctacagggatttgaaactggacaacatccttctggatgcagaaggtcactgcaagct ggctgacttcgggatgtgcaaggaagggattctgaatggtgtgacgaccaccacgttctgtgggactcctgactacatag ctcctgagatcctgcaggagttggagtatggcccctccgtggactggtgggccctgggggtgctgatgtacgagatgatg gctggacagcctccctttgaggccgacaatgaggacgacctatttgagtccatcctccatgacgacgtgctgtacccagt ctggctcagcaaggaggctgtcagcatcttgaaagctttcatgacgaagaatccccacaagcgcctgggctgtgtggcat cgcagaatggcgaggacgccatcaagcagcacccattcttcaaagagattgactgggtgctcctggagcagaagaagatc aagccacccttcaaaccacgcattaaaaccaaaagagacgtcaataattttgaccaagactttacccgggaagagccggt actcacccttgtggacgaagcaattgtaaagcagatcaaccaggaggaattcaaaggtttctcctactttggtgaagacc tgatgccctgagagcccactgcagttagccggcttctggaaactccctgtgtgagtgtgagggaatgagtatgaacaagg cacattatgtcttacttattgtattagtttcctgttgctgctgtagcaagttaccaccaatttatggcttaaagcaattc aaattttttctcttgaattcttaagatcagaagttctaaatgagtctaatggggctaaaatcaaggtgttaggcaaaggc agcttgcagctggagatccgggctcccacagcagatgagatccacgtaactgttggcgaggcccgtaacctaattcctat ggaccccaatggtctctctgatccctatgtgaaactgaagctcatcccagaccctcggaacctgacgaaacagaagaccc gaacggtgaaagccacgctaaaccctgtgtggaatgagacctttgtgttcaacctgaagccaggggatgtggagcgccgg ctcagcgtggaggtgtgggactgggaccggacctcccgcaacgacttcatgggggccatgtcctttggcgtctcggagct gctcaaggcgcccgtggatggctggtacaagttactgaaccaggaggagggcgagtattacaatgtgccggtggccgatg ctgacaactgcagcctcctccagaagtttgaggcttgtaactaccccctggaattgtatgagcgggtgcggatgggcccc tcttcctctcccatcccctccccttcccctagtcccaccgaccccaagcgctgcttcttcggggcgagtccaggacgcct gcacatctccgacttcagcttcctcatggttctaggaaaaggcagttttgggaaggtgatgctggccgagcgcaggggct ctgatgagctctacgccatcaagatcttgaaaaaggacgtgatcgtccaggacgacgatgtggactgcacgctggtggag aaacgtgtgctggcgctggggggccggggtcctggcggccggccccacttcctcacccagctccactccaccttccagac cccggaccgcctgtatttcgtgatggagtacgtcaccgggggagacttgatgtaccacattcaacagctgggcaagttta aggagccccatgcagcgttctacgcggcagaaatcgctatcggcctcttcttccttcacaatcagggcatcatctacagg gacctgaagctggacaatgtgatgctggatgctgagggacacatcaagatcactgactttggcatgtgtaaggagaacgt cttccccgggacgacaacccgcaccttctgcgggaccccggactacatagccccggagatcattgcctaccagccctatg ggaagtctgtcgattggtggtcctttggagttctgctgtatgagatgttggcaggacagcctcccttcgatggggaggac gaggaggagctgtttcaggccatcatggaacaaactgtcacctaccccaagtcgctttcccgggaagccgtggccatctg caaggggttcctgaccaagcacccagggaagcgcctgggctcagggcctgatggggaacctaccatccgtgcacatggct ttttccgctggattgactgggagcggctggaacgattggagatcccgcctcctttcagaccccgcccgtgtggccgcagc ggcgagaactttgacaagttcttcacgcgggcggcgccagcgctgacccctccagaccgcctagtcctggccagcatcga ccaggccgatttccagggcttcacctacgtgaaccccgacttcgtgcacccggatgcccgcagccccaccagcccagtgc ctgtgcccgtcatgtaatctcacccgccgccactaggtgtccccaacgtcccctccgccgtgccggcggcagccccactt cacccccaacttcaccaccccctgtcccattctagatcctgcaccccagcattccagctctgcccccgcgggttctagac gcccctcccaagcgttcctggccttctgaactccatacagcctctacagccgtcccgcgttcaagacttgagcgcggggt gtcttgggcccgggcggctgtagaggcggcggcgcctacgggcagtgggaggagccgcgcggttccggctgctccggcga ggcgacccttgggtcggcgctgcgggcaggtggcaggtaggtggcggacggccgcggttctccggcaagcgcaggcggcg gagtcccccacggcgcccgaagcgcccccccgcacccccggcctccagcgttgaggcgggggagtgaggagatgccgacc cagagggacagcagcaccatgtcccacacggtcgcaggcggcggcagcggggaccattcccaccaggtccgggtgaaagc ctactaccgcggggatatcatgataacacattttgaaccttccatctcctttgagggcctttgcaatgaggttcgagaca tgtgttcttttgacaacgaacagctcttcaccatgaaatggatagatgaggaaggagacccgtgtacagtatcatctcag ttggagttagaagaagcctttagactttatgagctaaacaaggattctgaactcttgattcatgtgttcccttgtgtacc agaacgtcctgggatgccttgtccaggagaagataaatccatctaccgtagaggtgcacgccgctggagaaagctttatt 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aacgaggagttttgcgctaacgtcaccgacggcggccacctcgagttggccgtcttccacgagacccccctgggctacga cttcgtggccaactgcaccctgcagttccaggagctcgtcggcacgaccggcgcctcggacaccttcgagggttgggtgg atctcgagccagaggggaaagtatttgtggtaataacccttaccgggagtttcactgaagctactctccagagagaccgg atcttcaaacattttaccaggaagcgccaaagggctatgcgaaggcgagtccaccagatcaatggacacaagttcatggc cacgtatctgaggcagcccacctactgctctcactgcagggagtttatctggggagtgtttgggaaacagggttatcagt gccaagtgtgcacctgtgtcgtccataaacgctgccatcatctaattgttacagcctgtacttgccaaaacaatattaac aaagtggattcaaagattgcagaacagaggttcgggatcaacatcccacacaagttcagcatccacaactacaaagtgcc aacattctgcgatcactgtggctcactgctctggggaataatgcgacaaggacttcagtgtaaaatatgtaaaatgaatg tgcatattcgatgtcaagcgaacgtggcccctaactgtggggtaaatgcggtggaacttgccaagaccctggcagggatg ggtctccaacccggaaatatttctccaacctcgaaactcgtttccagatcgaccctaagacgacagggaaaggagagcag caaagaaggaaatgggattggggttaattcttccaaccgacttggtatcgacaactttgagttcatccgagtgttgggga aggggagttttgggaaggtgatgcttgcaagagtaaaagaaacaggagacctctatgctgtgaaggtgctgaagaaggac gtgattctgctggatgatgatgtggaatgcaccatgaccgagaaaaggatcctgtctctggcccgcaatcaccccttcct cactcagttgttctgctgctttcagacccccgatcgtctgttttttgtgatggagtttgtgaatgggggtgacttgatgt tccacattcagaagtctcgtcgttttgatgaagcacgagctcgcttctatgctgcagaaatcatttcggctctcatgttc ctccatgataaaggaatcatcta agagatctgaaactggacaatgtcctgttggaccacgagggtcactgtaaactggc agacttcggaatgtgcaaggaggggatttgcaatggtgtcaccacggccacattctgtggcacgccagactatatcgctc cagagatcctccaggaaatgctgtacgggcctgcagtagactggtgggcaatgggcgtgttgctctatgagatgctctgt ggtcacgcgccttttgaggcagagaatgaagatgacctctttgaggccatactgaatgatgaggtggtctaccctacctg gctccatgaagatgccacagggatcctaaaatctttcatgaccaagaaccccaccatgcgcttgggcagcctgactcagg gaggcgagcacgccatcttgagacatcctttttttaaggaaatcgactgggcccagctgaaccatcgccaaatagaaccg cctttcagacccagaatcaaatcccgagaagatgtcagtaattttgaccctgacttcataaaggaagagccagttttaac tccaattgatgagggacatcttccaatgattaaccaggatgagtttagaaacttttcctatgtgtctccagaattgcaac catagccttatggggagtgagagagagggcacgagaacccaaaggaatagagattctccaggaatttcctctatcggacc ttcccagcatcagccttagaacaagaaccttaccttcaaggagcaagtgaagaactctgtcgaaggatggaactttcaga tatcaactatttagagtccgaattccttctctcctcctcctcgcccttctcctcgccctcctcctcctcctcgccctccc ctcccgatcctcatccccttgccctcccccagcccagggacttttccggaaagtttttattttccgtctgggctctcgga gaaagaagctcctggctcagcggctgcaaaactttcctgctgccgcgccgccagcccccgccctccgctgcccggccctg cgccccgccgagcgatgagcgcccctccggtcctgcggccgcccagtccgctgctgcccgtggcggcggcagctgccgca gcggccgccgcactggtcccagggtccgggcccgggcccgcgccgttcttggctcctgtcgcggccccggtcgggggcat ctcgttccatctgcagatcggcctgagccgtgagccggtgctgctgctgcaggactcgtccggggactacagcctggcgc acgtccgcgagatggcttgctccattgtcgaccagaagttccctgaatgtggtttctacggaatgtatgataagatcctg ctttttcgccatgaccctacctctgaaaacatccttcagctggtgaaagcggccagtgatatccaggaaggcgatcttat tgaagtggtcttgtcacgttccgccacctttgaagactttcagattcgtccccacgctctctttgttcattcatacagag ctccagctttctgtgatcactgtggagaaatgctgtgggggctggtacgtcaaggtcttaaatgtgaagggtgtggtctg aattaccataagagatgtgcatttaaaatacccaacaattgcagcggtgtgaggcggagaaggctctcaaacgtttccct cactggggtcagcaccatccgcacatcatctgctgaactctctacaagtgcccctgatgagccccttctgcaaaaatcac catcagagtcgtttattggtcgagagaagaggtcaaattctcaatcatacattggacgaccaattcaccttgacaagatt ttgatgtctaaagttaaagtgccgcacacatttgtcatccactcctacacccggcccacagtgtgccagtactgcaagaa gcttctgaaggggcttttcaggcagggcttgcagtgcaaagattgcagattcaactgccataaacgttgtgcaccgaaag taccaaacaactgccttggcgaagtgaccattaatggagatttgcttagccctggggcagagtctgatgtggtcatggaa gaagggagtgatgacaatgatagtgaaaggaacagtgggctcatggatgatatggaagaagcaatggtccaagatgcaga gatggcaatggcagagtgccagaacgacagtggcgagatgcaagatccagacccagaccacgaggacgccaacagaacca tcagtccatcaacaagcaacaatatcccactcatgagggtagtgcagtctgtcaaacacacgaagaggaaaagcagcaca gtcatgaaagaaggatggatggtccactacaccagcaaggacacgctgcggaaacggcactattggagattggatagcaa atgtattaccctctttcagaatgacacaggaagcaggtactacaaggaaattcctttatctgaaattttgtctctggaac cagtaaaaacttcagctttaattcctaatggggccaatcctcattgtttcgaaatcactacggcaaatgtagtgtattat gtgggagaaaatgtggtcaatccttccagcccatcaccaaataacagtgttctcaccagtggcgttggtgcagatgtggc caggatgtgggagatagσcatccagcatgcccttatgcccgtcattcccaagggctcctccgtgggtacaggaaccaact tgcacagagatatctctgtgagtatttcagtatcaaattgccagattcaagaaaatgtggacatcagcacagtatatcag atttttcctgatgaagtactgggttctggacagtttggaattgtttatggaggaaaacatcgtaaaacaggaagagatgt agctattaaaatcattgacaaattacgatttccaacaaaacaagaaagccagcttcgtaatgaggttgcaattctacaga accttcatcaccctggtgttgtaaatttggagtgtatgtttgagacgcctgaaagagtgtttgttgttatggaaaaactc catggagacatgctggaaatgatcttgtcaagtgaaaagggcaggttgccagagcacataacgaagtttttaattactca gatactcgtggctttgcggcaccttcattttaaaaatatcgttcactgtgacctcaaaccagaaaatgtgttgctagcct cagctgatccttttcctcaggtgaaactttgtgattttggttttgcccggatcattggagagaagtctttccggaggtca gtggtgggtacccccgcttacctggctcctgaggtcctaaggaacaagggctacaatcgctctctagacatgtggtctgt tggggtcatcatctatgtaagcctaagcggcacattcccatttaatgaagatgaagacatacacgaccaaattcagaatg cagctttcatgtatccaccaaatccctggaaggaaatatctcatgaagccattgatcttatcaacaatttgctgcaagta aaaatgagaaagcgctacagtgtggataagaccttgagccacccttggctacaggactatcagacctggttagatttgcg 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atgctcgctccagggcgcaaccatgtcgccatttcttcggattggcttgtccaactttgactgcgggtcctgccagtctt gtcagggcgaggctgttaacccttactgtgctgtgctcgtcaaagagtatgtcgaatcagagaacgggcagatgtatatc cagaaaaagcctaccatgtacccaccctgggacagcacttttgatgcccatatcaacaagggaagagtcatgcagatcat tgtgaaaggcaaaaacgtggacctcatctctgaaaccaccgtggagctctactcgctggctgagaggtgcaggaagaaca acgggaagacagaaatatggttagagctgaaacctcaaggccgaatgctaatgaatgcaagatactttctggaaatgagt gacacaaaggacatgaatgaatttgagacggaaggcttctttgctttgcatcagcgccggggtgccatcaagcaggcaaa ggtccaccacgtcaagtgccacgagttcactgccaccttcttcccacagcccacattttgctctgtctgccacgagtttg tctggggcctgaacaaacagggctaccagtgccgacaatgcaatgcagcaattcacaagaagtgtattgataaagttata gcaaagtgcacaggatcagctatcaatagccgagaaaccatgttccacaaggagagattcaaaattgacatgccacacag atttaaagtctacaattacaagagcccgaccttctgtgaacactgtgggaccctgctgtggggactggcacggcaaggac tcaagtgtgatgcatgtggcatgaatgtgcatcatagatgccagacaaaggtggccaacctttgtggcataaaccagaag ctaatggctgaagcgctggccatgattgagagcactcaacaggctcgctgcttaagagatactgaacagatcttcagaga aggtccggttgaaattggtctcccatgctccatcaaaaatgaagcaaggccgccatgtttaccgacaccgggaaaaagag agcctcagggcatttcctgggagtctccgttggatgaggtggataaaatgtgccatcttccagaacctgaactgaacaaa gaaagaccatctctgcagattaaactaaaaattgaggattttatcttgcacaaaatgttggggaaaggaagttttggcaa ggtcttcctggcagaattcaagaaaaccaatcaatttttcgcaataaaggccttaaagaaagatgtggtcttgatggacg atgatgttgagtgcacgatggtagagaagagagttctttccttggcctgggagcatccgtttctgacgcacatgttttgt acattccagaccaaggaaaacctcttttttgtgatggagtacctcaacggaggggacttaatgtaccacatccaaagctg ccacaagttcgacctttccagagcgacgttttatgctgctgaaatcattcttggtctgcagttccttcattccaaaggaa tagtctacagggacctgaagctagataacatcctgttagacaaagatggacatatcaagatcgcggattttggaatgtgc aaggagaacatgttaggagatgccaagacgaataccttctgtgggacacctgactacatcgccccagagatcttgctggg tcagaaatacaaccactctgtggactggtggtccttcggggttctcctttatgaaatgctgattggtcagtcgcctttcc acgggcaggatgaggaggagctcttccactccatccgcatggacaatcccttttacccacggtggctggagaaggaagca aaggaccttctggtgaagctcttcgtgcgagaacctgagaagaggctgggcgtgaggggagacatccgccagcacccttt gtttcgggagatcaactgggaggaacttgaacggaaggagattgacccaccgttccggccgaaagtgaaatcaccatttg actgcagcaatttcgacaaagaattcttaaacgagaagccccggctgtcatttgccgacagagcactgatcaacagcatg gaccagaatatgttcaggaacttttccttcatgaaccccgggatggagcggctgatatcctgaatcttgcccctccagag acaggaaagaatttgccttctccctgggaactggttcaagagacactgcttgggttcctttttcaacttggaaaaagaaa gaaacactcaacaataaagactgagacccgttcgcccccatgtgactttatctgtagcagaaaccaagtctacttcacta atgacgatgccgtgtgtctcgtctcctgacatgtctcacagacgctcctgaagttaggtcattactaaccatagttattt acttgaaagatgggtctccgcacttggaaaggtttcaagacttgatactgcaataaattatggctcttcacctgggcgcc aactgctgatcaacgaaatgcttgttgaatcaggggcaaacggagtacagacgtctcaagactgaaacggccccattgcc tggtctagtagcggatctcactcagccgcagacaagtaatcactaacccgttttattctatcctatctgtggatgtataa atgctgggggccagccctggataggtttttatgggaattctttacaataaacatagcttgtacttgatgcccagcaggac cgaccccaagatggaagggagcggcggccgcgtccgcctcaaggcgcattacgggggggacatcttcatcaccagcgtgg acgccgccacgaccttcgaggagctctgtgaggaagtgagagacatgtgtcgtctgcaccagcagcacccgctcaccctc aagtgggtggacagcgaaggtgacccttgcacggtgtcctcccagatggagctggaagaggctttccgcctggcccgtca gtgcagggatgaaggcctcatcattcatgttttcccgagcacccctgagcagcctggcctgccatgtccgggagaagaca aatctatctaccgccggggagccagaagatggaggaagctgtaccgtgccaacggccacctcttccaagccaagcgcttt aacaggagagcgtactgcggtcagtgcagcgagaggatatggggcctcgcgaggcaaggctacaggtgcatcaactgcaa actgctggtccataagcgctgccacggcctcgtcccgctgacctgcaggaagcatatggattctgtcatgccttcccaag agcctccagtagacgacaagaacgaggacgccgaccttccttccgaggagacagatggaattgcttacatttcctcatcc cggaagcatgacagcattaaagacgactcggaggaccttaagccagttatcgatgggatggatggaatcaaaatctctca ggggcttgggctgcaggactttgacctaatcagagtcatcgggcgcgggacgtacgccaaggttctcctggtgcggttga agaagaatgaccaaatttacgccatgaaagtggtgaagaaagagctggtgcatgatgacgaggatattgactgggtacag acagagaagcacgtgtttgagcaggcatccagcaaccccttcctggtcggattacactcctgcttccagacgacaagtcg gttgttcctggtcattgagtacgtcaacggcggggacctgatgttccacatgcagaggcagaggaagctccctgaggagc acgccaggttctacgcggccgagatctgcatcgccctcaacttcctgcacgagagggggatcatctacagggacctgaag ctggacaacgtcctcctggatgcggacggacacatcaagctcacagactacggcatgtgcaaggaaggcctgggccctgg tgacacaacgagcactttctgcggaaccccgaattacatcgcccccgaaatcctgcggggagaggagtacgggttcagcg tggactggtgggcgctgggagtcctcatgtttgagatgatggccgggcgctccccgttcgacatcatcaccgacaacccg gacatgaacacagaggactaccttttccaagtgatcctggagaagcccatccggatcccccggttcctgtccgtcaaagc ctcccatgttttaaaaggatttttaaataaggaccccaaagagaggctcggctgccggccacagactggattttctgaca tcaagtcccacgcgttcttccgcagcatagactgggacttgctggagaagaagcaggcgctccctccattccagccacag atcacagacgactacggtctggacaactttgacacacagttcaccagcgagcccgtgcagctgaccccagacgatgagga tgccataaagaggatcgaccagtcagagttcgaaggctttgagtatatcaacccattattgctgtccaccgaggagtcgg tgtgatgtcatgccttcccaagagcctccaggatggctgtcctccgacctcctccacctccaggctctagatggcaaagc ccacttagcaaaagccacctgctctgtgatgatgggactggctcctgcctgtgggttcggaaagcccatcccaccctcta cagcctcttgctcctctgcaatgactgtgccttcacctgggggttccccagagactagtgagagtcatcgggcgtggaag ctat (SEQ ID NO:12360) gccacttcttctgggcccacgaggcagctgtcccatgctctgctgagcacggtggtgccatgcctctgcaactcctcctg ttgctgatcctactgggccctggcaacagcttgcagctgtgggacacctgggcagatgaagccgagaaagccttgggtcc cctgcttgcccgggaccggagacaggccaccgaatatgagtacctagattatgatttcctgccagaaacggagcctccag aaatgctgaggaacagcactgacaccactcctctgactgggcctggaacccctgagtctaccactgtggagcctgctgca aggcgttctactggcctggatgcaggaggggcagtcacagagctgaccacggagctggccaacatggggaacctgtccac ggattcagcagctatggagatacagaccactcaaccagcagccacggaggcacagaccactccactggcagccacagagg cacagacaactcgactgacggccacggaggcacagaccactccactggcagccacagaggcacagaccactccaccagca gccacggaagcacagaccactcaacccacaggcctggaggcacagaccactgcaccagcagccatggaggcacagaccac tgcaccagcagccatggaagcacagaccactccaccagcagccatggaggcacagaccactcaaaccacagccatggagg cacagaccactgcaccagaagccacggaggcacagaccactcaacccacagccacggaggcacagaccactccactggca gccatggaggccctgtccacagaacccagtgccacagaggccctgtccatggaacctactaccaaaagaggtctgttcat acccttttctgtgtcctctgttactcacaagggcattcccatggcagccagcaatttgtccgtcaactacccagtggggg ccccagaccacatctctgtgaagcagtgcctgctggccatcctaatcttggcgctggtggccactatcttcttcgtgtgc actgtggtgctggcggtccgcctctcccgcaagggccacatgtaccccgtgcgtaattactcccccaccgagatggtctg catctcatccctgttgcctgatgggggtgaggggccctctgccacagccaatgggggcctgtccaaggccaagagcccgg gcctgacgccagagcccagggaggaccgtgagggggatgacctcaccctgcacagcttcctcccttagctcactctgcca tctgttttggcaagaccccacctccacgggctctcctgggccacccctgagtgcccagaccccaatccacagctctgggc ttcctcggagacccctggggatggggatcttcagggaaggaactctggccacccaaacaggacaagagcagcctggggcc aagcagacgggcaagtggagccacctctttcctccctccgcggatgaagcccagccacatttcagccgaggtccaaggca ggaggccatttacttgagacagattctctcctttttcctgtcccccatcttctctgggtccctctaacatctcccatggc tctccccgcttctcctggtcactggagtctcctccccatgtacccaagg (SEQ ID NO: 12361) ccaccaatcttgggcaagaagcgagaccattctcctttttctctggtcactcctgtccttcagggggctccctctggccc cgactgtccattgctgctgaagtaatgctgtggcctttctcagtttgggccccacccaaaaccgaagaacttctccccag aagcttctacttggttctcagtgttttcacagttatgggaacccaagaacagtgtcagacctaggaggtgccccactacc accctgtctttatcaatgttgtcaccaaagctgtcacaaacaatggggtgtgggctgtcacatggccctgcctaagtaac cacattctcgcttcctccttccacacacagccattgggggttgctcggatccgggactgccgcagggggtgccacagcag tgcctggcagcgtgggctgggaccttgtcactaaagcagagaagccacttcttctgggcccacgaggcagctgtcccatg ctctgctgagcacggtggtaagtgctggcttgcaaaaccacagggagtggctggaggtccccatgggccaagggcctgcc ttatagctgctggcaggcccgggtaggaccgccaggcccttcttgagctgcagcacctggggagggcaaactgaggctcc tccgactcaagactaaagtcttcctggagtctgtggccttattctgtgactcttctgaatcct (SEQ ID NO:12362) tagaagaagttaaagggccctcctggatggctttattcatgttgatgagtaataataataactgctactggctgaggatc ttctccatcccaggcatgtcagggatgcctaagtccccagtccctgctccagaccagacatcttccagctgtggcagtag agggtggtggtctagggtgcttgctaagcccaagggtgaaactgtcttgacatccctccgcccattgtctcctcctaggt gccatgcctctgcaactcctcctgttgctgatcctactgggccctggcaacagcttgcagctgtgggacacctgggcaga tgaagccgagaaagccttgggtcccctgcttgcccgggaccggagacaggccaccgaatatgagtacctagattatgatt tcctgccagaaacggagcctccagaaatgctgaggaacagcactgacaccactcctctgactgggcctggaacccctgag tctaccactgtggagcctgctgcaaggcgttctactggcctggatgcaggaggggcagtcacagagctgaccacggagct ggccaacatggggaacctgtccacggattcagcagctatggagatacagaccactcaaccagcagccacggaggcacaga ccactcaaccagtgcccacggaggcacagaccactccactggcagccacagaggcacagacaactcgactgacggccacg gaggcacagaccactccactggcagccacagaggcacagaccactccaccagcagccacggaagcacagaccactcaacc cacaggcctggaggcacagaccactgcaccagcagccatggaggcacagaccactgcaccagcagccatggaagcacaga ccactccaccagcagccatggaggcacagaccactcaaaccacagccatggaggcacagaccactgcaccagaagccacg gaggcacagaccactcaacccacagccacggaggcacagaccactccactggcagccatggaggccctgtccacagaacc cagtgccacagaggccctgtccatggaacctactaccaaaagaggtctgttcatacccttttctgtgtcctctgttactc acaagggcattcccatggcagccagcaatttgtccgtcaactacccagtgggggccccagaccacatctctgtgaagcag tgcctgctggccatcctaatcttggcgctggtggccactatcttcttcgtgtgcactgtggtgctggcggtccgcctctc ccgcaagggccacatgtaccccgtgcgtaattactcccccaccgagatggtctgcatctcatccctgttgcctgatgggg gtgaggggccctctgccacagccaatgggggcctgtccaaggccaagagcccgggcctgacgccagagcccagggaggac cgtgagggggatgacctcaccctgcacagcttcctcccttagctcactctgccatctgttttggcaagaccccacctcca cgggctctcctgggccacccctgagtgcccagaccccaatccacagctctgggcttcctcggagacccctggggatgggg atcttcagggaaggaactctggccacccaaacaggacaagagcagcctggggccaagcagacgggcaagtggagccacct ctttcctccctccgcggatgaagcccagccacatttcagccgaggtccaaggcaggaggccatttacttgagacagattc tctcctttttcctgtcccccatcttctctgggtccctctaacatctcccatggctctccccgcttctcctggtcactgga gtctcctccccatgtacccaaggaagatggagctcccccatcccacacgcactgcactgccattgtcttttggttgccat ggtcaccaaacaggaagtggacattctaagggaggagtactgaagagtgacggacttctgaggctgtttcctgctgctcc tctgacttggggcagcttgggtcttcttgggcacctctctgggaaaacccagggtgaggttcagcctgtgagggctggga tgggtttcgtgggcccaaagggcagacctttctttgggactgtgtggaccaaggagcttccatctagtgacaagtgaccc ccagctatcgcctcttgccttcccctgtggccactttccagggtggactctgtcttgttcactgcagtatcccaactgca ggtccagtgcaggcaataaatatgtgatggacaaaacgatagcggaatccttcaaggtttcaaggctgtctccttcaggc agccttcccggaattctccatccctcagtgcaggatgggggctggtcctcagctgtctgccctcagcccctggcccccca ggaagcctctttcatgggctgttaggttgacttcagttttgcctcttggacaacagggggtcttgtacatccttgggtga ccaggaaaagttcaggctatggggggccaaagggagggctgccccttccccaccagtgaccactttattccacttcctcc attacccagttttggcccacagagtttggtcccccccaaacctcggaccaatatccctctaaacatcaatctatcctcct gttaaagaaaaaaaaaaatgggactgggagcagtggctcatgcctgtaatcccagcactttgggaggccgaggcaggtac atcacctgaggtcaggagttcaagactagcctggccaacatagtgaaaccctgtctctactaaaaatacaaagattagtc aggtgtggtggcacatgcctgtagtcccagctactggggaggctgaggcaggagaattgcttgaacccgggaagcggagg gaggttgcagtgagctgagatcacgctactgcactccagcctgggtgacagagtaagactccgtctcaaaaaaaaaaaaa aagattcaatgacccttgttaaagcatggtaaggaagactttgttcaaggggagtgggactctctcaatcactgcaggga ctgcagctatgggattttgcagtgggggcatttgggctcaactatgagtacagcaggggcaagtgggagctgatagccag ggaacagggttggatatctgcagctggaaaattaccaagaggaaacatcaggggaaggggaattctggctaaactgactg ctggggatgggttctcggtcattttctacactgacctaacaggattcatactggaggcaggccagggtgctcagacatca ccggggggatggtggcagatgaggaacgtgatcagatataggaggtgatcagatatgggaggtgatcagatatggagtgg tggggggagggttgttgctaagctgacttagcagagttcttgttagaac (SEQ ID NO: 12363) tagaagaagttaaagggccctcctggatggctttattcatgttgatgagtaataataataactgctactggctgaggatc ttctccatcccaggcatgtcagggatgcctaagtccccagtccctgctccagaccagacatcttccagctgtggcagtag agggtggtggtctagggtgcttgctaagcccaagggtgaaactgtcttgacatccctccgcccattgtctcctcctaggt gccatgcctctgcaactcctcctgttgctgatcctactgggccctggcaacagcttgcagctgtgggacacctgggcaga tgaagccgagaaagccttgggtcccctgcttgcccgggaccggagacaggccaccgaatatgagtacctagattatgatt tcctgccagaaacggagcctccagaaatgctgaggaacagcactgacaccactcctctgactgggcctggaacccctgag tctaccactgtggagcctgctgcaaggcgttctactggcctggatgcaggaggggcagtcacagagctgaccacggagct ggccaacatggggaacctgtccacggattcagcagctatggagatacagaccactcaaccagcagccacggaggcacaga ccactcaaccagtgcccacggaggcacagaccactccactggcagccacagaggcacagacaactcgactgacggccacg gaggcacagaccactccactggcagccacagaggcacagaccactccaccagcagccacggaagcacagaccactcaacc cacaggcctggaggcacagaccactgcaccagcagccatggaggcacagaccactgcaccagcagccatggaagcacaga ccactccaccagcagccatggaggcacagaccactcaaaccacagccatggaggcacagaccactgcaccagaagccacg gaggcacagaccactcaacccacagccacggaggcacagaccactccactggcagccatggaggccctgtccacagaacc cagtgccacagaggccctgtccatggaacctactaccaaaagaggtctgttcatacccttttctgtgtcctctgttactc acaagggcattcccatggcagccagcaatttgtccgtcaactacccagtgggggccccagaccacatctctgtgaagcag tgcctgctggccatcctaatcttggcgctggtggccactatcttcttcgtgtgcactgtggtgctggcggtccgcctctc ccgcaagggccacatgtaccccgtgcgtaat ac cccccaccgagatggtctgcatctca ccctgttgcctgatgggg gtgaggggccctctgccacagccaatgggggcctgtccaaggccaagagcccgggcctgacgccagagcccagggaggac cgtgagggggatgacctcaccctgcacagcttcctcccttagctcactctgccatctgttttggcaagaccccacctcca cgggctctcctgggccacccctgagtgcccagaccccaatccacagctctgggcttcctcggagacccctggggatgggg atcttcagggaaggaactctggccacccaaacaggacaagagcagcctggggccaagcagacgggcaagtggagccacct ctttcctccctccgcggatgaagcccagccacatttcagccgaggtccaaggcaggaggccatttacttgagacagattc tctcctttttcctgtcccccatcttctctgggtccctctaacatctcccatggctctccccgcttctcctggtcactgga gtctcctccccatgtacccaaggaagatggagctcccccatcccacacgcactgcactgccattgtcttttggttgccat ggtcaccaaacaggaagtggacattctaagggaggagtactgaagagtgacggacttctgaggctgtttcctgctgctcc tctgacttggggcagcttgggtcttcttgggcacctctctgggaaaacccagggtgaggttcagcctgtgagggctggga tgggtttcgtgggcccaaagggcagacctttctttgggactgtgtggaccaaggagcttccatctagtgacaagtgaccc ccagctatcgcctcttgccttcccctgtggccactttccagggtggactctgtcttgttcactgcagtatcccaactgca ggtccagtgcaggcaataaatatgtgatggacaaaacgatagcggaatccttcaaggtttcaaggctgtctccttcaggc agccttcccggaattctccatccctcagtgcaggatgggggctggtcctcagctgtctgccctcagcccctggcccccca ggaagcctctttcatgggctgttaggttgacttcagttttgcctcttggacaacagggggtcttgtacatccttgggtga ccaggaaaagttcaggctatggggggccaaagggagggctgccccttccccaccagtgaccactttattccacttcctcc attacccagttttggcccacagagtttggtcccccccaaacctcggaccaatatccctctaaacatcaatctatcctcct gttaaagaaaaaaaaaaatgggactgggagcagtggctcatgcctgtaatcccagcactttgggaggccgaggcaggtac atcacctgaggtcaggagttcaagactagcctggccaacatagtgaaaccctgtctctactaaaaatacaaagattagtc aggtgtggtggcacatgcctgtagtcccagctactggggaggctgaggcaggagaattgcttgaacccgggaagcggagg gaggttgcagtgagctgagatcacgctactgcactccagcctgggtgacagagtaagactccgtctcaaaaaaaaaaaaa aagattcaatgacccttgttaaagcatggtaaggaagactttgttcaaggggagtgggactctctcaatcactgcaggga ctgcagctatgggattttgcagtgggggcatttgggctcaactatgagtacagcaggggcaagtgggagctgatagccag ggaacagggttggatatctgcagctggaaaattaccaagaggaaacatcaggggaaggggaattctggctaaactgactg ctggggatgggttctcggtcattttctacactgacctaacaggattcatactggaggcaggccagggtgctcagacatca ccggggggatggtggcagatgaggaacgtgatcagatataggaggtgatcagatatgggaggtgatcagatatggagtgg tggggggagggttgttgctaagctgacttagcagagttcttgttagaac (SEQ ID NO:12364) gccacttcttctgggcccacgaggcagctgtcccatgctctgctgagcacggtggtgccatgcctctgcaactcctcctg ttgctgatcctactgggccctggcaacagcttgcagctgtgggacacctgggcagatgaagccgagaaagccttgggtcc cctgcttgcccgggaccggagacaggccaccgaatatgagtacctagattatgatttcctgccagaaacggagcctccag aaatgctgaggaacagcactgacaccactcctctgactgggcctggaacccctgagtctaccactgtggagcctgctgca aggcgttctactggcctggatgcaggaggggcagtcacagagctgaccacggagctggccaacatggggaacctgtccac ggattcagcagctatggagatacagaccactcaaccagcagccacggaggcacagaccactccactggcagccacagagg cacagacaactcgactgacggccacggaggcacagaccactccactggcagccacagaggcacagaccactccaccagca gccacggaagcacagaccactcaacccacaggcctggaggcacagaccactgcaccagcagccatggaggcacagaccac tgcaccagcagccatggaagcacagaccactccaccagcagccatggaggcacagaccactcaaaccacagccatggagg cacagaccactgcaccagaagccacggaggcacagaccactcaacccacagccacggaggcacagaccactccactggca gccatggaggccctgtccacagaacccagtgccacagaggccctgtccatggaacctactaccaaaagaggtctgttcat acccttttctgtgtcctctgttactcacaagggcattcccatggcagccagcaatttgtccgtcaactacccagtggggg ccccagaccacatctctgtgaagcagtgcctgctggccatcctaatcttggcgctggtggccactatcttcttcgtgtgc actgtggtgctggcggtccgcctctcccgcaagggccacatgtaccccgtgcgtaattactcccccaccgagatggtctg catctcatccctgttgcctgatgggggtgaggggccctctgccacagccaatgggggcctgtccaaggccaagagcccgg gcctgacgccagagcccagggaggaccgtgagggggatgacctcaccctgcacagcttcctcccttagctcactctgcca tctgttttggcaagaccccacctccacgggctctcctgggccacccctgagtgcccagaccccaatccacagctctgggc ttcctcggagacccctggggatggggatcttcagggaaggaactctggccacccaaacaggacaagagcagcctggggcc aagcagacgggcaagtggagccacctctttcctccctccgcggatgaagcccagccacatttcagccgaggtccaaggca ggaggccatttacttgagacagattctctcctttttcctgtcccccatcttctctgggtccctctaacatctcccatggc tctccccgcttctcctggtcactggagtctcctccccatgtacccaaggccaccaatcttgggcaagaagcgagaccatt ctcctttttctctggtcactcctgtccttcagggggctccctctggccccgactgtccattgctgctgaagtaatgctgt ggcctttctcagtttgggccccacccaaaaccgaagaacttctccccagaagcttctacttggttctcagtgttttcaca gttatgggaacccaagaacagtgtcagacctaggaggtgccccactaccaccctgtctttatcaatgttgtcaccaaagc tgtcacaaacaatggggtgtgggctgtcacatggccctgcctaagtaaccacattctcgcttcctccttccacacacagc cattgggggttgctcggatccgggactgccgcagggggtgccacagcagtgcctggcagcgtgggctgggaccttgtcac taaagcagagaagccacttcttctgggcccacgaggcagctgtcccatgctctgctgagcacggtggtaagtgctggctt gcaaaaccacagggagtggctggaggtccccatgggccaagggcctgccttatagctgctggcaggcccgggtaggaccg ccaggcccttcttgagctgcagcacctggggagggcaaactgaggctcctccgactcaagactaaagtcttcctggagtc tgtggccttattctgtgactcttctgaatccttagaagaagttaaagggccctcctggatggctttattcatgttgatga gtaataataataactgctactggctgaggatcttctccatcccaggcatgtcagggatgcctaagtccccagtccctgct ccagaccagacatcttccagctgtggcagtagagggtggtggtctagggtgcttgctaagcccaagggtgaaactgtctt gacatccctccgcccattgtctcctcctaggtgccatgcctctgcaactcctcctgttgctgatcctactgggccctggc aacagcttgcagctgtgggacacctgggcagatgaagccgagaaagccttgggtcccctgcttgcccgggaccggagaca ggccaccgaatatgagtacctagattatgatttcctgccagaaacggagcctccagaaatgctgaggaacagcactgaca ccactcctctgactgggcctggaacccctgagtctaccactgtggagcctgctgcaaggcgttctactggcctggatgca ggaggggcagtcacagagctgaccacggagctggccaacatggggaacctgtccacggattcagcagctatggagataca gaccactcaaccagcagccacggaggcacagaccactcaaccagtgcccacggaggcacagaccactccactggcagcca cagaggcacagacaactcgactgacggccacggaggcacagaccactccactggcagccacagaggcacagaccactcca ccagcagccacggaagcacagaccactcaacccacaggcctggaggcacagaccactgcaccagcagccatggaggcaca gaccactgcaccagcagccatggaagcacagaccactccaccagcagccatggaggcacagaccactcaaaccacagcca tggaggcacagaccactgcaccagaagccacggaggcacagaccactcaacccacagccacggaggcacagaccactcca ctggcagccatggaggccctgtccacagaacccagtgccacagaggccctgtccatggaacctactaccaaaagaggtct gttcatacccttttctgtgtcctctgttactcacaagggcattcccatggcagccagcaatttgtccgtcaactacccag tgggggccccagaccacatctctgtgaagcagtgcctgctggccatcctaatcttggcgctggtggccactatcttcttc gtgtgcactgtggtgctggcggtccgcctctcccgcaagggccacatgtaccccgtgcgtaattactcccccaccgagat ggtctgcatctcatccctgttgcctgatgggggtgaggggccctctgccacagccaatgggggcctgtccaaggccaaga gcccgggcctgacgccagagcccagggaggaccgtgagggggatgacctcaccctgcacagcttcctcccttagctcact ctgccatctgttttggcaagaccccacctccacgggctctcctgggccacccctgagtgcccagaccccaatccacagct ctgggcttcctcggagacccctggggatggggatcttcagggaaggaactctggccacccaaacaggacaagagcagcct ggggccaagcagacgggcaagtggagccacctctttcctccctccgcggatgaagcccagccacatttcagccgaggtcc aaggcaggaggccatttacttgagacagattctctcctttttcctgtcccccatcttctctgggtccctctaacatctcc catggctctccccgcttctcctggtcactggagtctcctccccatgtacccaaggaagatggagctcccccatcccacac gcactgcactgccattgtcttttggttgccatggtcaccaaacaggaagtggacattctaagggaggagtactgaagagt gacggacttctgaggctgtttcctgctgctcctctgacttggggcagcttgggtcttcttgggcacctctctgggaaaac ccagggtgaggttcagcctgtgagggctgggatgggtttcgtgggcccaaagggcagacctttctttgggactgtgtgga ccaaggagcttccatctagtgacaagtgacccccagctatcgcctcttgccttcccctgtggccactttccagggtggac tctgtcttgttcactgcagtatcccaactgcaggtccagtgcaggcaataaatatgtgatggacaaaacgatagcggaat ccttcaaggtttcaaggctgtctccttcaggcagccttcccggaattctccatccctcagtgcaggatgggggctggtcc tcagctgtctgccctcagcccctggccccccaggaagcctctttcatgggctgttaggttgacttcagttttgcctcttg gacaacagggggtcttgtacatccttgggtgaccaggaaaagttcaggctatggggggccaaagggagggctgccccttc cccaccagtgaccactttattccacttcctccattacccagttttggcccacagagtttggtcccccccaaacctcggac caatatccctctaaacatcaatctatcctcctgttaaagaaaaaaaaaaatgggactgggagcagtggctcatgcctgta atcccagcactttgggaggccgaggcaggtacatcacctgaggtcaggagttcaagactagcctggccaacatagtgaaa ccctgtctctactaaaaatacaaagattagtcaggtgtggtggcacatgcctgtagtcccagctactggggaggctgagg caggagaattgcttgaacccgggaagcggagggaggttgcagtgagctgagatcacgctactgcactccagcctgggtga cagagtaagactccgtctcaaaaaaaaaaaaaaagattcaatgacccttgttaaagcatggtaaggaagactttgttcaa ggggagtgggactctctcaatcactgcagggactgcagctatgggattttgcagtgggggcatttgggctcaactatgag tacagcaggggcaagtgggagctgatagccagggaacagggttggatatctgcagctggaaaattaccaagaggaaacat caggggaaggggaattctggctaaactgactgctggggatgggttctcggtcattttctacactgacctaacaggattca tactggaggcaggccagggtgctcagacatcaccggggggatggtggcagatgaggaacgtgatcagatataggaggtga tcagatatgggaggtgatcagatatggagtggtggggggagggttgttgctaagctgacttagcagagttcttgttagaa ctagaagaagttaaagggccctcctggatggctttattcatgttgatgagtaataataataactgctactggctgaggat cttctccatcccaggcatgtcagggatgcctaagtccccagtccctgctccagaccagacatcttccagctgtggcagta gagggtggtggtctagggtgcttgctaagcccaagggtgaaactgtcttgacatccctccgcccattgtctcctcctagg tgccatgcctctgcaactcctcctgttgctgatcctactgggccctggcaacagcttgcagctgtgggacacctgggcag atgaagccgagaaagccttgggtcccctgcttgcccgggaccggagacaggccaccgaatatgagtacctagattatgat ttcctgccagaaacggagcctccagaaatgctgaggaacagcactgacaccactcctctgactgggcctggaacccctga gtctaccactgtggagcctgctgcaaggcgttctactggcctggatgcaggaggggcagtcacagagctgaccacggagc tggccaacatggggaacctgtccacggattcagcagctatggagatacagaccactcaaccagcagccacggaggcacag accactcaaccagtgcccacggaggcacagaccactccactggcagccacagaggcacagacaactcgactgacggccac ggaggcacagaccactccactggcagccacagaggcacagaccactccaccagcagccacggaagcacagaccactcaac ccacaggcctggaggcacagaccactgcaccagcagccatggaggcacagaccactgcaccagcagccatggaagcacag accactccaccagcagccatggaggcacagaccactcaaaccacagccatggaggcacagaccactgcaccagaagccac ggaggcacagaccactcaacccacagccacggaggcacagaccactccactggcagccatggaggccctgtccacagaac ccagtgccacagaggccctgtccatggaacctactaccaaaagaggtctgttcatacccttttctgtgtcctctgttact cacaagggcattcccatggcagccagcaatttgtccgtcaactacccagtgggggccccagaccacatctctgtgaagca gtgcctgctggccatcctaatcttggcgctggtggccactatcttcttcgtgtgcactgtggtgctggcggtccgcctct cccgcaagggccacatgtaccccgtgcgtaattactcccccaccgagatggtctgcatctcatccctgttgcctgatggg ggtgaggggccctctgccacagccaatgggggcctgtccaaggccaagagcccgggcctgacgccagagcccagggagga ccgtgagggggatgacctcaccctgcacagcttcctcccttagctcactctgccatctgttttggcaagaccccacctcc acgggctctcctgggccacccctgagtgcccagaccccaatccacagctctgggcttcctcggagacccctggggatggg gatcttcagggaaggaactctggccacccaaacaggacaagagcagcctggggccaagcagacgggcaagtggagccacc tctttcctccctccgcggatgaagcccagccacatttcagccgaggtccaaggcaggaggccatttacttgagacagatt ctctcctttttcctgtcccccatcttctctgggtccctctaacatctcccatggctctccccgcttctcctggtcactgg agtctcctccccatgtacccaaggaagatggagctcccccatcccacacgcactgcactgccattgtcttttggttgcca tggtcaccaaacaggaagtggacattctaagggaggagtactgaagagtgacggacttctgaggctgtttcctgctgctc ctctgacttggggcagcttgggtcttcttgggcacctctctgggaaaacccagggtgaggttcagcctgtgagggctggg atgggtttcgtgggcccaaagggcagacctttctttgggactgtgtggaccaaggagcttccatctagtgacaagtgacc cccagctatcgcctcttgccttcccctgtggccactttccagggtggactctgtcttgttcactgcagtatcccaactgc aggtccagtgcaggcaataaatatgtgatggacaaaacgatagcggaatccttcaaggtttcaaggctgtctccttcagg cagccttcccggaattctccatccctcagtgcaggatgggggctggtcctcagctgtctgccctcagcccctggcccccc aggaagcctctttcatgggctgttaggttgacttcagttttgcctcttggacaacagggggtcttgtacatccttgggtg accaggaaaagttcaggctatggggggccaaagggagggctgccccttccccaccagtgaccactttattccacttcctc cattacccagttttggcccacagagtttggtcccccccaaacctcggaccaatatccctctaaacatcaatctatcctcc tgttaaagaaaaaaaaaaatgggactgggagcagtggctcatgcctgtaatcccagcactttgggaggccgaggcaggta catcacctgaggtcaggagttcaagactagcctggccaacatagtgaaaccctgtctctactaaaaatacaaagattagt caggtgtggtggcacatgcctgtagtcccagctactggggaggctgaggcaggagaattgcttgaacccgggaagcggag ggaggttgcagtgagctgagatcacgctactgcactccagcctgggtgacagagtaagactccgtctcaaaaaaaaaaaa aaagattcaatgacccttgttaaagcatggtaaggaagactttgttcaaggggagtgggactctctcaatcactgcaggg actgcagctatgggattttgcagtgggggcatttgggctcaactatgagtacagcaggggcaagtgggagctgatagcca gggaacagggttggatatctgcagctggaaaattaccaagaggaaacatcaggggaaggggaattctggctaaactgact gctggggatgggttctcggtcattttctacactgacctaacaggattcatactggaggcaggccagggtgctcagacatc accggggggatggtggcagatgaggaacgtgatcagatataggaggtgatcagatatgggaggtgatcagatatggagtg gtggggggagggttgttgctaagctgacttagcagagttcttgttagaac (SEQ ID NO:12365) cctgcctgcacggcacaggagagcaaacttctacagacagaccaaggcttccatttgctgctgacacatggaactgaggt gaaattgtgctccatgattttacagatttcataacgtttaagagacgggactcaggtcatcaaaatgaaagccctcatct ttgcagctgctggcctcctgcttctgttgcccactttttgtcagagtggcatggaaaatgatacaaacaacttggcaaag ccaaccttacccattaagacctttcgtggagctcccccaaattcttttgaagagttccccttttctgccttggaaggctg gacaggagccacgattactgtaaaaattaagtgccctgaagaaagtgcttcacatctccatgtgaaaaatgctaccatgg ggtacctgaccagctccttaagtactaaactgatacctgccatctacctcctggtgtttgtagttggtgtcccggccaat gctgtgaccctgtggatgcttttcttcaggaccagatccatctgtaccactgtattctacaccaacctggccattgcaga ttttcttttttgtgttacattgccctttaagatagcttatcatctcaatgggaacaactgggtatttggagaggtcctgt gccgggccaccacagtcatcttctatggcaacatgtactgctccattctgctccttgcctgcatcagcatcaaccgctac ctggccatcgtccatcctttcacctaccggggcctgcccaagcacacctatgccttggtaacatgtggactggtgtgggc aacagttttcttatatatgctgccatttttcatactgaagcaggaatattatcttgttcagccagacatcaccacctgcc atgatgttcacaacacttgcgagtcctcatctcccttccaactctattacttcatctccttggcattctttggattctta attccatttgtgcttatcatctactgctatgcagccatcatccggacacttaatgcatacgatcatagatggttgtggta tgttaaggcgagtctcctcatccttgtgatttttaccatttgctttgctccaagcaatattattcttattattcaccatg ctaactactactacaacaacactgatggcttatattttatatatctcatagctttgtgcctgggtagtcttaatagttgc ttagatccattcctttattttctcatgtcaaaaaccagaaatcactccactgcttaccttacaaaatagtgaaatgatct tagagaacaaggacagccatcacagagaacgtctgttttcaagaacaacataagcatagtgcaaggagctccatttccga gctcctaagaaatatgcttcaaaggtcaaacattacaaaagcattagtagtttgtttgtttgtttttgagactgagtctc actttatcacccagactggcgtgcagtggcactatcttggctcattgcaacctctgcctcccaggtcagcctcccaagta gctgggattacaccaccatgcccagctactaaaaatacttgtatttttagtagagacggggtttcaccatgttgaccagg ctggtcttgaactcctgacctcaagtgatcttccggcctcagcctcccaaagtgctggattacaggcgtgagccactgag ccagccagcattagtaatttttaaaaacactttatcagtattttaaaaatgttaatgcaggagaaaagatatcacaactc tatggaaaatgacatttccatttgccttattgctacttcaagctctttaaatcaccatcttccctatttc (SEQ ID NO: 12366) tcatgtgggggcgactgctcctgtggcccctggtgctggggttcagcctgtctggcggcacccagacccccagcgtctac gacgagagcgggagcaccggaggtggtgatgacagcacgccctcaatcctgcctgccccccgcggctacccaggccaagt ctgtgccaatgacagtgacaccctggagctcccggacagctcacgggcactgcttctgggctgggtgcccaccaggctgg tgcccgccctctatgggctggtcctggtggtggggctgccggccaatgggctggcgctgtgggtgctggccacgcaggca cctcggctgccctccaccatgctgctgatgaacctcgcgactgctgacctcctgctggccctggcgctgcccccgcggat cgcctaccacctgcgtggccagcgctggcccttcggggaggccgcctgccgcctggccacggccgcactctatggtcaca tgtatggctcagtgctgctgctggccgccgtcagcctggatcgctacctggccctggtgcacccgctgcgggcccgcgcc ctgcgtggccggcgcctggcccttggactctgcatggctgcttggctcatggcggccgccctggcactgcccctgacact gcagcggcagaccttccggctggcgcgctccgatcgcgtgctctgccatgacgcgctgcccctggacgcacaggcctccc actggcaaccggccttcacctgcctggcgctgttgggctgtttcctgcccctgctggccatgctgctgtgctacggggcc accctgcacacgctggcggccagcggccggcgctacggccacgcgctgaggctgaccgcagtggtgctggcctccgccgt ggccttcttcgtgcccagcaacctgctgctgctgctgcattactcggacccgagccccagcgcctggggcaacctctatg gtgcctacgtgcccagcctggcgctgagcaccctcaacagctgcgtggatcccttcatctactactacgtgtcggccgag ttcagggacaaggtgcgggcagggctcttccaacggtcgccgggggacaccgtggcctccaaggcctctgcggaaggggg cagccggggcatgggcacccactcctctttgctccagtgacacaaagtggggaaggctgtactgggtcgaacagggtccc ttcccccacttcacgtccttcctgggacctcagaatgtgaccttatttggaaatagggttgttacaactgtcactagcag aggtcactttggagaagggtgggccttacatccagtgtgggtggtgtcctcataagataaggagaggccaggcctggtgg ctcacgcctgtaatcccagcactttaagaggccaaggcggatggatcacttgagcccaggagttcaacaccagcctgagc aacatggtaaaaccccatctctaccaaaaatacaaaaattagctgggcttggtggctggcgcctgtaatcccagctactc angagactgaggca (SEQ ID NO: 12367) cgcacccgggcccgcaggccagaatcaaaagcaacaaatgccaccttagatccccggtcatttcttctcaggaaccccaa tgataaatatgaaccattttgggaggatgaggagaaaaatgaaagtgggttaactgaatacagattagtctccatcaata aaagcagtcctcttcaaaaacaacttcctgcattcatctcagaagatgcctccggatatttgaccagctcctggctgaca ctctttgtcccatctgtgtacaccggagtgtttgtagtcagcctcccactaaacatcatggccatcgttgtgttcatcct gaaaatgaaggtcaagaagccggcggtggtgtacatgctgcacctggccacggcagatgtgctgtttgtgtctgtgctcc cctttaagatcagctattacttttccggcagtgattggcagtttgggtctgaattgtgtcgcttcgtcactgcagcattt tactgtaacatgtacgcctctatcttgctcatgacagtcataagcattgaccggtttctggctgtggtgtatcccatgca gtccctctcctggcgtactctgggaagggcttccttcacttgtctggccatctgggctttggccatcgcaggggtagtgc ctctcgtcctcaaggagcaaaccatccaggtgcccgggctcaacatcactacctgtcatgatgtgctcaatgaaaccctg ctcgaaggctactatgcctactacttctcagccttctctgctgtcttcttttttgtgccgctgatcatttccacggtctg ttatgtgtctatcattcgatgtcttagctcttccgcagttgccaaccgcagcaagaagtcccgggctttgttcctgtcag ctgctgttttctgcatcttcatcatttgcttcggacccacaaacgtcctcctgattgcgcattactcattcctttctcac acttccaccacagaggctgcctactttgcctacctcctctgtgtctgtgtcagcagcataagctcgtgcatcgaccccct aatttactattacgcttcctctgagtgccagaggtacgtctacagtatcttatgctgcaaagaaagttccgatcccagca gttataacagcagtgggcagttgatggcaagtaaaatggatacctgctctagtaacctgaataacagcatatacaaaaag ctgttaacttaggaaaagggactgctgggaggttaaaaagaaaagtttataaaagtgaataacctgaggattctattagt ccccacccaaactttattgattcacctcctaaaacaacagatgtacgacttgcatacctgctttttatgggagctgtcaa gcatgtatttttgtcaattaccagaaagataacaggacgagatgacggtgttattccaagggaatattgccaatgctaca gtaataaatgaatgtcacttctggatatagctaggtgacatatacatacttacatgtgtgtatatgtagatgtatgcaca cacatatattatttgcagtgcagtatagaataggcactttaaaacactctttccccgcaccccagcaattatgaaaataa tctctgattccctgatttaatatgcaaagtctaggttggtagagtttagccctgaacatttcatggtgttcatcaacagt gagagactccatagtttgggcttgtaccacttttgcaaataagtgtattttgaaattgtttgacggcaaggtttaagtta ttaagaggtaagacttagtactatctgtgcgtagaagttctagtgttttcaattttaaacatatccaagtttgaattcct aaaattatggaaacagatgaaaagcctctgttttgatatgggtagtattttttacattttacacactgtacacataagcc aaaactgagcataagtcctctagtgaatgtaggctggctttcagagtaggctattcctgagagctgcatgtgtccgcccc cgatggaggactccaggcagcagacacatgccagggccatgtcagacacagattggccagaaaccttcctgctgagcctc acagcagtgagactggggccactacatttgctccatcctcctgggattggctgtgaactgatcatgtttatgagaaactg gcaaagcagaatgtgatatcctaggaggtaatgaccatgaaagacttctctacccatcttaaaaacaacgaaagaaggca tggacttctggatgcccatccactgggtgtaaacacatctagtagttgttctgaaatgtcagttctgatatggaagcacc cattatgcgctgtggccactccaataggtgctgagtgtacagagtggaataagacagagacctgccctcaagagcaaagt agatcatgcatagagtgtgatgtatgtgtaataaatatgtttcacacaaacaaggcctgtcagctaaagaagtttgaaca tttgggttactatttcttgtggttataacttaatgaaaacaatgcagtacaggacatatattttttaaaataagtctgat ttaattgggcactatttatttacaaatgttttgctcaatagattgctcaaatcaggttttcttttaagaatcaatcatgt cagtctgcttagaaataacagaagaaaatagaattgacattgaaatctaggaaaattattctataatttccatttactta agacttaatgagactttaaaagcattttttaacctcctaagtatcaagtatagaaaatcttcatggaattcacaaagtaa tttggaaattaggttgaaacatatctcttatcttacgaaaaaatggtagcattttaaacaaaatagaaagttgcaaggca aatgtttatttaaaagagcaggccaggcgcggtggctcacgcctgtaatcccagcactttgggaggctgaggcgggtgga tcacgaggtcaggagatcgagaccatcctggctaacacggtgaaacccgtctctactaaaaatgcaaaaaaaattagccg ggcgtggtggcaggcacctgtagtcccagctactcgggaggctgaggcaggagactggcgtgaacccaggaggcggacct tgtagtgagccgagatcgcgccactgtgctccagcctgggcaacagagcaagactccatctc (SEQ ID NO: 12368) cctgcctgcacggcacaggagagcaaacttctacagacagaccaaggcttccatttgctgctgacacatggaactgaggt gaaattgtgctccatgattttacagatttcataacgtttaagagacgggactcaggtcatcaaaatgaaagccctcatct ttgcagctgctggcctcctgcttctgttgcccactttttgtcagagtggcatggaaaatgatacaaacaacttggcaaag ccaaccttacccattaagacctttcgtggagctcccccaaattcttttgaagagttccccttttctgccttggaaggctg gacaggagccacgattactgtaaaaattaagtgccctgaagaaagtgcttcacatctccatgtgaaaaatgctaccatgg ggtacctgaccagctccttaagtactaaactgatacctgccatctacctcctggtgtttgtagttggtgtcccggccaat gctgtgaccctgtggatgcttttcttcaggaccagatccatctgtaccactgtattctacaccaacctggccattgcaga ttttcttttttgtgttacattgccctttaagatagcttatcatctcaatgggaacaactgggtatttggagaggtcctgt gccgggccaccacagtcatcttctatggcaacatgtactgctccattctgctccttgcctgcatcagcatcaaccgctac ctggccatcgtccatcctttcacctaccggggcctgcccaagcacacctatgccttggtaacatgtggactggtgtgggc aacagttttcttatatatgctgccatttttcatactgaagcaggaatattatcttgttcagccagacatcaccacctgcc atgatgttcacaacacttgcgagtcctcatctcccttccaactctattacttcatctccttggcattctttggattctta attccatttgtgctta catctactgctatgcagccatcatccggacacttaatgcatacgatcatagatggttgtggta tgttaaggcgagtctcctcatccttgtgatttttaccatttgctttgctccaagcaatattattcttattattcaccatg ctaactactactacaacaacactgatggcttatattttatatatctcatagctttgtgcctgggtagtcttaatagttgc ttagatccattcctttattttctcatgtcaaaaaccagaaatcactccactgcttaccttacaaaatagtgaaatgatct tagagaacaaggacagccatcacagagaacgtctgttttcaagaacaacataagcatagtgcaaggagctccatttccga gctcctaagaaatatgcttcaaaggtcaaacattacaaaagcattagtagtttgtttgtttgtttttgagactgagtctc actttatcacccagactggcgtgcagtggcactatcttggctcattgcaacctctgcctcccaggtcagcctcccaagta gctgggattacaccaccatgcccagctactaaaaatacttgtatttttagtagagacggggtttcaccatgttgaccagg ctggtcttgaactcctgacctcaagtgatcttccggcctcagcctcccaaagtgctggattacaggcgtgagccactgag ccagccagcattagtaatttttaaaaacactttatcagtattttaaaaatgttaatgcaggagaaaagatatcacaactc tatggaaaatgacatttccatttgccttattgctacttcaagctctttaaatcaccatcttccctatttctcatgtgggg gcgactgctcctgtggcccctggtgctggggttcagcctgtctggcggcacccagacccccagcgtctacgacgagagcg ggagcaccggaggtggtgatgacagcacgccctcaatcctgcctgccccccgcggctacccaggccaagtctgtgccaat gacagtgacaccctggagctcccggacagctcacgggcactgcttctgggctgggtgcccaccaggctggtgcccgccct ctatgggctggtcctggtggtggggctgccggccaatgggctggcgctgtgggtgctggccacgcaggcacctcggctgc cctccaccatgctgctgatgaacctcgcgactgctgacctcctgctggccctggcgctgcccccgcggatcgcctaccac ctgcgtggccagcgctggcccttcggggaggccgcctgccgcctggccacggccgcactctatggtcacatgtatggctc agtgctgctgctggccgccgtcagcctggatcgctacctggccctggtgcacccgctgcgggcccgcgccctgcgtggcc ggcgcctggcccttggactctgcatggctgcttggctcatggcggccgccctggcactgcccctgacactgcagcggcag accttccggctggcgcgctccgatcgcgtgctctgccatgacgcgctgcccctggacgcacaggcctcccactggcaacc ggccttcacctgcctggcgctgttgggctgtttcctgcccctgctggccatgctgctgtgctacggggccaccctgcaca cgctggcggccagcggccggcgctacggccacgcgctgaggctgaccgcagtggtgctggcctccgccgtggccttcttc gtgcccagcaacctgctgctgctgctgcattactcggacccgagccccagcgcctggggcaacctctatggtgcctacgt gcccagcctggcgctgagcaccctcaacagctgcgtggatcccttcatctactactacgtgtcggccgagttcagggaca aggtgcgggcagggctcttccaacggtcgccgggggacaccgtggcctccaaggcctctgcggaagggggcagccggggc atgggcacccactcctctttgctccagtgacacaaagtggggaaggctgtactgggtcgaacagggtcccttcccccact tcacgtccttcctgggacctcagaatgtgaccttatttggaaatagggttgttacaactgtcactagcagaggtcacttt ggagaagggtgggccttacatccagtgtgggtggtgtcctcataagataaggagaggccaggcctggtggctcacgcctg taatcccagcactttaagaggccaaggcggatggatcacttgagcccaggagttcaacaccagcctgagcaacatggtaa aaccccatctctaccaaaaatacaaaaattagctgggcttggtggctggcgcctgtaatcccagctactcangagactga ggcacgcacccgggcccgcaggccagaatcaaaagcaacaaatgccaccttagatccccggtcatttcttctcaggaacc ccaatgataaatatgaaccattttgggaggatgaggagaaaaatgaaagtgggttaactgaatacagattagtctccatc aataaaagcagtcctcttcaaaaacaacttcctgcattcatctcagaagatgcctccggatatttgaccagctcctggct gacactctttgtcccatctgtgtacaccggagtgtttgtagtcagcctcccactaaacatcatggccatcgttgtgttca tcctgaaaatgaaggtcaagaagccggcggtggtgtacatgctgcacctggccacggcagatgtgctgtttgtgtctgtg ctcccctttaagatcagctattacttttccggcagtgattggcagtttgggtctgaattgtgtcgcttcgtcactgcagc attttactgtaacatgtacgcctctatcttgctcatgacagtcataagcattgaccggtttctggctgtggtgtatccca tgcagtccctctcctggcgtactctgggaagggcttccttcacttgtctggccatctgggctttggccatcgcaggggta gtgcctctcgtcctcaaggagcaaaccatccaggtgcccgggctcaacatcactacctgtcatgatgtgctcaatgaaac cctgctcgaaggctactatgcctactacttctcagccttctctgctgtcttcttttttgtgccgctgatcatttccacgg tctgttatgtgtctatcattcgatgtcttagctcttccgcagttgccaaccgcagcaagaagtcccgggctttgttcctg tcagctgctgttttctgcatcttcatcatttgcttcggacccacaaacgtcctcctgattgcgcattactcattcctttc tcacacttccaccacagaggctgcctactttgcctacctcctctgtgtctgtgtcagcagcataagctcgtgcatcgacc ccctaatttactattacgcttcctctgagtgccagaggtacgtctacagtatcttatgctgcaaagaaagttccgatccc agcagttataacagcagtgggcagttgatggcaagtaaaatggatacctgctctagtaacctgaataacagcatatacaa aaagctgttaacttaggaaaagggactgctgggaggttaaaaagaaaagtttataaaagtgaataacctgaggattctat tagtccccacccaaactttattgattcacctcctaaaacaacagatgtacgacttgcatacctgctttttatgggagctg tcaagcatgtatttttgtcaattaccagaaagataacaggacgagatgacggtgttattccaagggaatattgccaatgc tacagtaataaatgaatgtσacttctggatatagctaggtgacatatacatacttacatgtgtgtatatgtagatgtatg cacacacatatattatttgcagtgcagtatagaataggcactttaaaacactctttccccgcaccccagcaattatgaaa ataatctctgattccctgatttaatatgcaaagtctaggttggtagagtttagccctgaacatttcatggtgttcatcaa cagtgagagactccatagtttgggcttgtaccacttttgcaaataagtgtattttgaaattgtttgacggcaaggtttaa gttattaagaggtaagacttagtactatctgtgcgtagaagttctagtgttttcaattttaaacatatccaagtttgaat tcctaaaattatggaaacagatgaaaagcctctgttttgatatgggtagtattttttacattttacacactgtacacata agccaaaactgagcataagtcctctagtgaatgtaggctggctttcagagtaggctattcctgagagctgcatgtgtccg cccccgatggaggactccaggcagcagacacatgccagggccatgtcagacacagattggccagaaaccttcctgctgag cctcacagcagtgagactggggccactacatttgctccatcctcctgggattggctgtgaactgatcatgtttatgagaa actggcaaagcagaatgtgatatcctaggaggtaatgaccatgaaagacttctctacccatcttaaaaacaacgaaagaa ggcatggacttctggatgcccatccactgggtgtaaacacatctagtagttgttctgaaatgtcagttctgatatggaag cacccattatgcgctgtggccactccaataggtgctgagtgtacagagtggaataagacagagacctgccctcaagagca aagtagatcatgcatagagtgtgatgtatgtgtaataaatatgtttcacacaaacaaggcctgtcagctaaagaagtttg aacatttgggttactatttcttgtggttataacttaatgaaaacaatgcagtacaggacatatattttttaaaataagtc tgatttaattgggcactatttatttacaaatgttttgctcaatagattgctcaaatcaggttttcttttaagaatcaatc atgtcagtctgcttagaaataacagaagaaaatagaattgacattgaaatctaggaaaattattctataatttccattta cttaagacttaatgagactttaaaagcattttttaacctcctaagtatcaagtatagaaaatcttcatggaattcacaaa gtaatttggaaattaggttgaaacatatctcttatcttacgaaaaaatggtagcattttaaacaaaatagaaagttgcaa ggcaaatgtttatttaaaagagcaggccaggcgcggtggctcacgcctgtaatcccagcactttgggaggctgaggcggg tggatcacgaggtcaggagatcgagaccatcctggctaacacggtgaaacccgtctctactaaaaatgcaaaaaaaatta gccgggcgtggtggcaggcacctgtagtcccagctactcgggaggctgaggcaggagactggcgtgaacccaggaggcgg accttgtagtgagccgagatcgcgccactgtgctccagcctgggcaacagagcaagactccatctc (SEQ ID NO: 12369) ggtgbcbttgbgcbtgtcggcgcggtcccgttbbgbgtgggcccgccagcccagccactccacttgggggcgggtggcca gcacgaacagcacccagaggaaggggggcggcccagaagggcagcccgcaggccaggatcaggtctgctgcggccggaga taatggcattcaccacgcggcggcccagcgcacgccgcgcatccg'gcccgggttctgacctgcagcccccgtctccttgg cattcctgggccccagtcactcctctccctgccccccttgctggggcagggacggggtgbcbttgbgcbtgtcggcgcgg tcccgttbbgbgtgggcccgccagcccagccactccacttgggggcgggtggccagcacgaacagcacccagaggaaggg gggcggcccagaagggcagcccgcaggccaggatcaggtctgctgcggccggagataatggcattcaccacgcggcggcc cagcgcacgccgcgcatccggcccgggttctgacctgcagcccccgtctccttggcattcctgggccccagtcactcctc tccctgccccccttgctggggcagggacggccgtgttgtcbgtggtgctgcccgtttgbggtbtggcgctccbccbbttc ccttttctccttgttttccgtttctcttgccgtctgtggttcagattcacaaactgcaggactgggcagggagcagacag tgagcaaacgccagcagggctgctgtgaatttgtgtaaggattgagggacagttgcttttcagcatgggcccaggaatgc caaggagacatctatgcacgaccttgggaaatgagttgatgtctccggtaaaacaccggagactaattcctgccctgccc aattttgcagggagcatggctgtgaggatggggtgaactcacgcacagccaaggactccaaaatcacaacagcattactg ttcttatttgctgccacacctgagccagcctgctccttcccaggagtggaggaggcctggggggagggagaggagtgact gagcttccctcccgtgtgttctccgtccctgccccagcaagacaacttagatctccaggagaactgccatccagctttgg tgcaatggctgagtgcacaagtgagttgttgccctgggtttctttaatctattcagctagaactttgaaggacaatttct tgcattaataaaggttaagccctgaggggtccctgataacaacctggagaccaggattttatggctcccctcactgatgg acaaggaggtctgtgccaaagaagaatccaataagcacatattgagcacttgctgtatatgcagtattgagcactgtagg caagacccaagaaagagaaggagccatctccatcttgaaggaactcaaagactcaagtgggaacgactgggcactgccac caccagaaagctgttcgacgagacggtcgagcagggtgctgtgggtgatatggacagcagaagggggagaccaaggttcc agctcaaccaataactattgcacaaccacctgtccctgcctcagttcccttttatgtaacatgaagtcgttgtgagggtt aaaggcagtaacaggtataaagtacttagaaaagcaaagggtgctacgtacatgtgaggcatcattacgcagacgtaact gggatatgtttactataaggaaaagacactgaggtctagaaatagctccgtggagcagaatcagtattgggagccggtgg cggtgtgaagcaccagtgtctggcacacagtaggtgctcattggctcccttccacctgtcattcccaccaccctgaggcc ccaaccgccacacacacaggagcatttggagagaaggccatgtcttcaaagtctgatttgtgatgaggcagaggaagata tttctaatcggtcttgcccagaggatcacagtgctgagaccccccaccaccagccggtacctgggaagggggagagtgca ggcctgctcagggactgttcctgtctcagcaaccaagggattgttcctgtcaatcaatggtttattggaaggtggcccag tatgagccctagaagagtgtgaaaaggaatggcaatggtgttcaccatcggcagtgccagggcagcactcattcacttga taaatgaatatttattagctggttggagagctagaacctggagagctagaacctggagaactagaacctggagggctaga acctggagaggctagaaccaagaagggctagaacctggaggggctagaacctagagaagctaaaacctgagctagaagct ggaggactagaacctggagggctggaatctgaagggctagaacctggagggctggaatctggagagctagaacctggagg gctagaacctggagggctagaacctagaagggctagaacctggagggctggaatctggagagctagaacctggagggcta gaacctggagggctagaacctagaagggctagaacctggagggctagaacctggcaggttagaacctagaagggctagaa cctggagagccagaacctggagggctagaacctggaagggctagaacctgtagagctagaacatggagagctagaacccg gcaggctagaacctggcaagctagaacctggagggaatgaacctggagggctagaacctggagaatgagaaaaatttaca tggcaaagagcccataaatcctgaccaatccaactctgaattttaaagcaaaagcgtgaaaaaaaagattccctccttac ccccaacccactcttttttcccaccacccactctcctctgcctcagtaagtatctggaggaagaaaacaggtgaaagaag aagtaaaaaccatttagtattagtattagaatgaagtcaaactgtgccacacatggtgaatgaaaaaaaaaaaaaagagg ctgtgttttgtcacacagggcagtcattcagcaccagagcacgtgatggtctgagactctcttaggagcagagctctgcc gcaatggccatgtggggatccacacctggtctgaggggcaactgagtctgcgggagaagagcggccctatgcatggtgta gatgccctgataaagaacatctgtcctgtgaaagactcaatgagctgttatgttgtaaacaggaagcatttcacatccaa acgagaaaatcatgtaaacatgtgtcttttctgtagagcataataaatggatgaggtttttgcaaaaaaaaaaaaaaaaa aaatgatagaccgtcaataatttgttaaatgctttttaaaatgaatgctttaagccgggtgcagtgcctcacatctgtaa tcccagcactttggagccgagcgggtggattgtgtgaggtcaggagttcgagaccaacctggccaacatggcaaaacctc actctctaccaaaaatacaaaaattagccaggcatggtggcaggcacctgtgatcccagctactcaggaggctgagacag gagaatcgcttgaacccgggaggcaaggttgcagtgagccaagattacgccattgtactccagcctgggtgacagagaga gactccgtctcaaaaaaaaaaaaaaaaaaaaaaaaattacgcttcaaacacatgatctctcaccactgttgaattttctt tctatgagcccaggagggcctctcagagaggaaagctcctaggtcttcctttccctctgcaaactccctgccttgaaggt tcagaaggactgtgcgtgctcgttgcatcctttgcaagtgtccaaaccctgatcccagctgtgcttaggggttcctgcaa accttttccaggtgttaattacctcccacttcatttcctgtttaccaactcagctttttgttttagtgtgtttgaattcc ctgaactgaccgttgtctgatctccacctcccaactgaattaggggagctgggcttctggaaacccaggtgccgggtgtt gcagagtggctgaaagctgggatgtggcagatccgtggctacattcatgcacacacacacacccacatacccacacatgc acacacacacacacacccgcactcacacacttggacatgcatagaccacagctttccacacccttcctagacaggggtca cttggtatcctggagagagtgtgaagtcctggaatggaaagaggggggattaagccccacctctagccatgggactgaga caagtcaccaccaacccatctgcgccttgtttacctcctctgtgaggcaagcacagagcccatgcctgcccccctggatg ggagtgatgtgaaacttgaagggcggtcagagcaagggtcgggaatggaaggcccttgggaaaaaaggccctttcaacta ggggcacagaggaggccctgggctgagaacttgacagcaccttgtaattggtaagccaagcccgaagggactggaaatac tcagatgtgtctgtctcccttattaggttcaaagtccctcaagaccctgtctccatcacagtgctccagtccagacccct cctctgagctccagaccctgctggacccaaccagccctatggggtcgcatccccacctgcctggaattctccaaagaacc tcccctttaacagttccagcctttaacagttccagtctaaacacatgacctttctcctctaaatcagccccccatctctg cctttgcaggagatggaagccatgacacctgcctcgcccctgtcctcaccccatccatgtccaatcaagcactaggcatg tcaggtttaccctctaaactcctctggaatccagtctctcagtctccatcatcccaggtcgaagctaatgggctaactgg tccttgcttccactctacccccactgcagtcctgacttcctgagcagcagccagggcctaatcgatattcacaccaagcg ccaacctgactgagatatcctcctgcaccatcatccctccaccctgtttagttctgctcaccctcagtgttctcatcaat aatccactcccctcacaggcgcgtttgggaccccatgttctatgctctcacaggaccttttgcttgatttttcactgtac ttaggtcagtttgcagttattaagtgactgagcaatgtctggcttctccagtagactgtcagctcctagccattgtatac ctagcaccgctgtgtgggagcacgtgacaaacgtccagtgagtcagggactcagcagtctccatttctccgccctgctgg agaatgcgtgtatttggcaatccccagcccctgtgccatctaaccatcttttcttctctgttcagcccaggtgtggcctc actcacatcccactctgagtccaaatgttctctccctggaagatatcaatgtttctgtctgttcgtgaggactccgtgcc caccacggcctctttcaggtgagtcaaagggattcctcagttcactagttaggggaggtgggcagacaccctggagaact ccctggaaagctcaactctcatgccccggacaacagttgaaggaaccatggtgatgttaagcccaaagacaaaacctctc aggtgtccaagtccctgttggaatcttgggagcagagggaatgttctgtggtctagaggaagaggggctcagggaggaga agggcacattcctggttgttatatgtttctatc atcccagatgaacttggaagtgaagggaagagagttaaacattaaa gtaaatacccagtggatcagacagcaatgtgccagattgccttggaaacaaaatatctccaacacatggctgacatttgg tgggagatcagaacaccctaaagagagaatttaaggggagggggaggaggacctgagccagagtagaagcagaggatagg gagatctgttcttggggacagcatttgcaagaaacaaggctgaggggtccactccaacctctccaccctgctgcaggtgc tgcctatgatgaagatgagcagatggccatctcagctggggccacagtgcactggacctatagtttccaattccgcactc agcaggcatctttctgatgatccgatggcttctcagagccagggatgggccaggatccatccccttggctactgtcttgc tgagaaatttataagcagcatctggtgctatactttggtctctagtgagttagctcatgaaagatgatagactctccaag ccaggggtatgcaggaaatgggttttctgtagctacagaaatggggttgagggttggaccaagggactacccaggggaag tcttaccttcagaggactctggaaaggaggctgcaagttttcatgggtcaagaattcagagcccagtagagacagcttat ctctgttccaagatgtctggggccttggttggaagattcaaaggctaggaaaccaggagccaccaaaagcgtaactgggg ccagaggatccactttcaaggtggcaagttggttccccccatgtggctgcttgagtatcctcacatggcggctcacatcc ttccaagtaagcaatgcaaaaggccaagaaagatgctgcaaagatgttatgacctagcctcagaaatcacacaccatccc tgccaccattagtaagaagtccagcccacgtccaggagaagaggaagcagattcctccttttgaaatgaagaatatcaag taattcggggggcatatgaaagccaccacacaccacagggatctttttagagcatacttcttataccatcactgtagttc cttaagactcaggggcaaagcctcacttccttagcacccagtgaagaccacgcttactccctcactcaacctcttgctac ttcccacctctcctgtccaacatctagtgtcactttccagaacataccaacagcttccccagttctgtgcctctgctcag gctgttccccctgcctggtccacttgtcctccttcttgtccggtcaaaatgcttcttatccttcaagacccagctctaga gtcacctccaaccccttacccaccagccccctctccaagtctgtgtcccacaacccccctgctccctccagggcaccctc caccctctgggccacagttgtcaggagtcaggcagggcaggggccgggtggtgtcttctttgtgttcttgcactcagggc agagctcagcacagagcagacgctcaaaaaacatttaaaggatagaagcattgatttgtgggtcccccagtctggctcca ggatgccagccagctgctcctagaagcaaacggacttttcctgggaaatcccagaggtgatgatcagtaatctctcccgt gactcgtagttcagctcttcctccatgagcctgactatcagtggaccttccagaaagagccccttttccttctctcaccc acagcacagggcactgggaaaatgcccaatgagtcctgcctctgggttgtgctttggacttttcagtgtgtctcgcatcc actcttcaacttgaatgttgcaacagccatgaaaaaagaaatgcaaagcgattcaggatgagagcaataccctactccaa agaaggcaacatagaagctcagagagatcaagcaatttgcccaagaccacacagctaggagtggaactcatggctgtcca agccccatgcctctgctgaaggtagagatgaattacagcaacaagtctagaaaggtgcctgccctatggtctgtgagtct tgcctaagaatgaaagaggagccagtgggttaaagatgaggtcaccaacaacggtggtgttggagtttaccactgataat aagggtgcaaaatgtaaattactaatgtttattgagcctagtgcagtgcgtggggcattttgcacattgtctctgatccc tatgacaaccctgagaggtagtggttttaactgccatgttacaggtgaggtcattgtggttcaaggacgttaagtaactt ccccagcgtgacacggcttataagtaaggcagccaggatgtgaacccagtaggactatctggctgcaaagtccccacccc cctcgccatctgtatcctccaatcacttcagtgctttgctgcatagaaggtaacggaaatcacgatgccacagactgtcc aggaagacagaaactaggcagatgggctggccatggtctccaagccagactggaatctccaggtctggaatgatatcatt tttctcttttaataaattaactcacccaccacacggctttgagaggctcaaagttgaccaactcccttgggagggccccg gttgataaggaaggaacgtgaatcctcccatcacggaagcttcaaggaggtcaagggtccaacacttgagattgttagtg ctgttggtggatactggccaaggaaatatcccagtggagcctcgagatgaagaacatgaggcccccgtttagaaccaagg atcagagggggctctgtaagacccaggggagtcaggtgcactggagcgcgggcatgcagaaaacagcctgagctccacct cggcttctccttgtcctggctggttgtccttaacccctgtctccttctggaccagtttttgtccttcccttgtgaccgct gaggggtaacagcctctttccactttctttcagcgccgacatgctcaatgtcaccttgcaagggcccactcttaacggga cctttgcccagagcaaatgcccccaagtggagtggctgggctggctcaacaccatccagccccccttcctctgggtgctg ttcgtgctggccaccctagagaacatctttgtcctcagcgtcttctgcctgcacaagagcagctgcacggtggcagagat ctacctggggaacctggccgcagcagacctgatcctggcctgcgggctgcccttctgggccatcaccatctccaacaact tcgactggctctttggggagacgctctgccgcgtggtgaatgccattatctccatgaacctgtacagcagcatctgtttc ctgatgctggtgagcatcgaccgctacctggccctggtgaaaaccatgtccatgggccggatgcgcggcgtgcgctgggc caagctctacagcttggtgatctgggggtgtacgctgctcctgagctcacccatgctggtgttccggaccatgaaggagt acagcgatgagggccacaacgtcaccgcttgtgtcatcagctacccatccctcatctgggaagtgttcaccaacatgctc ctgaatgtcgtgggcttcctgctgcccctgagtgtcatcaccttctgcacgatgcagatcatgcaggtgctgcggaacaa cgagatgcagaagttcaaggagatccagacggagaggagggccacggtgctagtcctggttgtgctgctgctattcatca tctgctggctgcccttccagatcagcaccttcctggatacgctgcatcgcctcggcatcctctccagctgccaggacgag cgcatcatcgatgtaatcacacagatcgcctccttcatggcctacagcaacagctgcctcaacccactggtgtacgtgat cgtgggcaagcgcttccgaaagaagtcttgggaggtgtaccagggagtgtgccagaaagggggctgcaggtcagaaccca ttcagatggagaactccatgggcacactgcggacctccatctccgtggaacgccagattcacaaactgcaggactgggca gggagcagacagtgagcaaacgccagcagggctgctgtgaatttgtgtaaggattgagggacagttgcttttcagcatgg gcccaggaatgccaaggagacatctatgcacgaccttgggaaatgagttgatgtctccggtaaaacaccggagactaatt cctgccctgcccaattttgcagggagcatggctgtgaggatggggtgaactcacgcacagccaaggactccaaaatcaca acagcattactgttcttatttgctgccacacctgagccagcctgctccttcccaggagtggaggaggcctgggggcaggg agaggagtgactgagcttccctcccgtgtgttctccgtccctgccccagcaagacaacttagatctccaggagaactgcc atccagctttggtgcaatggctgagtgcacaagtgagttgttgccctgggtttctttaatctattcagctagaactttga aggacaatttcttgcattaataaaggttaagccctgaggggtccctgataacaacctggagaccaggattttatggctcc cctcactgatggacaaggaggtctgtgccaaagaagaatccaataagcacatattgagcacttgctgtatatgcagtatt gagcactgtaggcaagagggaagaaagagaaggagccatctccatcttgaaggaactcaaagactcaagtgggaacgact gggcactgccaccaccagaaagctgttcgatgagacggtcgagcagggtgctgtgggtgatatggacagcagaaggggga gccaggttccagctcaccaatactattgcacaccacctgtcctgcctcgcccttcaaagatgagctgttcccgccgccac tccagctctggcttctgggctccgaggaggggtggggacggtggtgacggtggggacatcaggctgccccgcagtaccag ggagcgactgaagtgcccatgccgcttgctccggagaaggtgggtgccgggcaggggctgctccagccgcctcacctctg ctgggaggacaaactgtcccagcacagagggagggagggagggcaggcagcggggagaagtttccctgtggtcgtgggga gttgagctcttcaatattttagtgaaagctatagatgaggctccataggggataaagcacagacacaccttttcagaggg cttgtggactctgggcagcctgtccatagacctctgtccccaactggcaagtcaggaaactccagattaaggagccccaa tgtggttgaacagccaggtgcacagatgagtcaaccacacagccaggccagggagggccttcactcaagagcctacagcc agttcacagccaagccagggctagcgccaggccacccataaactgatctgagactctgtttccctgtctccatgatgatg ggatcaggcttgattgctggtttgtaggcttgttatgaatcaagtcacagggaagaggagctgatgggctggggggacgt cctctggccctcctgtctcttccccagatccactgggcccactcttatctgttctcttctgaaggaagggttttaaggct tcaaaaaaaaatgttttgaaagtccctgccctttccagctcctaccgtctcagccctgggagtgtaaagtgctgcagata gttagtaagtctttgagcaaaactgagaaagccagcctgagccttgacatgggagaaacctccgccatacatctccgaag aaacggccgcgtgtctcaggggagcgcaaacacccgtacccaggaaacaggacagcttctgccactgtcgcccttgggag ccgtacgtggcatgacaaagaaatcccaggactccgcctgcccacctggccaccctctgtttacaccttccgcgtaaacg cccactgtttacatccaaaactcagacacaaaataaccacctcaagaagataaataatgataagaaataaatgttacgcg aggcaaatttattcacatggggcttcccaggccactttgtggtcagccgggagggacgtttttgccgtcccacgactcca acgggcagccgggcctacgcaaacatggaaatcttccaagagcctccctggcccccagggctcagagggtggcagagcgg agagcgaaggtggccgcagccttcccggccccacagccagcctggctccagctgggcaggagtgcagagctcagctggag gcgagggggaagtgcccaggaggctgatgacatcactacccagcccttcaaagatgagctgttcccgccgccactccagc tctggcttctgggctccgaggaggggtggggacggtggtgacggtggggacatcaggctgccccgcagtaccagggagcg actgaagtgcccatgccgcttgctccggagaaggtgggtgccgggcaggggctgctccagccgcctcacctctgctggga ggacaaactgtcccagcacagagggagggagggagggcaggcagcggggagaagtttccctgtggtcgtggggagttggg aaaagttcccttccttccggagggaggcagattcacaaactgcaggactgggcagggagcagacagtgagcaaacgccag cagggctgctgtgaatttgtgtaaggattgagggacagttgcttttcagcatgggcccaggaatgccaaggagacatcta tgcacgaccttgggaaatgagttgatgtctccggtaaaacaccggagactaattcctgccctgcccaattttgcagggag catggctgtgaggatggggtgaactcacgcacagccaaggactccaaaatcacaacagcattactgttcttatttgctgc cacacctgagccagcctgctccttcccaggagtggaggaggcctggggggagggagaggagtgactgagcttccctcccg tgtgttctccgtccctgccccagcaagacaacttagatctccaggagaactgccatccagctttggtgcaatggctgagt gcacaagtgagttgttgccctgggtttctttaatctattcagctagaactttgaaggacaatttcttgcattaataaagg ttaagccctgaggggtccctgataacaacctggagaccaggattttatggctcccctcactgatggacaaggaggtctgt gccaaagaagaatccaataagcacatattgagcacttgctgtatatgcagtattgagcactgtaggcaagacccaagaaa gagaaggagccatctccatcttgaaggaactcaaagactcaagtgggaacgactgggcactgccaccaccagaaagctgt tcgacgagacggtcgagcagggtgctgtgggtgatatggacagcagaagggggagaccaaggttccagctcaaccaataa ctattgcacaaccacctgtccctgcctcagttcccttttatgtaacatgaagtcgttgtgagggttaaaggcagtaacag gtataaagtacttagaaaagcaaagggtgctacgtacatgtgaggcatcattacgcagacgtaactgggatatgtttact ataaggaaaagacactgaggtctagaaatagctccgtggagcagaatcagtattgggagccggtggcggtgtgaagcacc agtgtctggcacacagtaggtgctcattggctcccttccacctgtcattcccaccaccctgaggccccaaccgccacaca cacaggagcatttggagagaaggccatgtcttcaaagtctgatttgtgatgaggcagaggaagatatttctaatcggtct tgcccagaggatcacagtgctgagaccccccaccaccagccggtacctgggaagggggagagtgcaggcctgctcaggga ctgttcctgtctcagcaaccaagggattgttcctgtcaatcaatggtttattggaaggtggcccagtatgagccctagaa gagtgtgaaaaggaatggcaatggtgttcaccatcggcagtgccagggcagcactcattcacttgataaatgaata tta ttagctggttggagagctagaacctggagagctagaacctggagaactagaacctggagggctagaacctggagaggcta gaaccaagaagggctagaacctggaggggctagaacctagagaagctaaaacctgagctagaagctggaggactagaacc tggagggctggaatctgaagggctagaacctggagggctggaatctggagagctagaacctggagggctagaacctggag ggctagaacctagaagggctagaacctggagggctggaatctggagagctagaacctggagggctagaacctggagggct agaacctagaagggctagaacctggagggctagaacctggcaggttagaacctagaagggctagaacctggagagccaga acctggagggctagaacctggaagggctagaacctgtagagctagaacatggagagctagaacccggcaggctagaacct ggcaagctagaacctggagggaatgaacctggagggctagaacctggagaatgagaaaaatttacatggcaaagagccca taaatcctgaccaatccaactctgaattttaaagcaaaagcgtgaaaaaaaagattccctccttacccccaacccactct tttttcccaccacccactctcctctgcctcagtaagtatctggaggaagaaaacaggtgaaagaagaagtaaaaaccatt tagtattagtattagaatgaagtcaaactgtgccacacatggtgaatgaaaaaaaaaaaaaagaggctgtgttttgtcac acagggcagtcattcagcaccagagcacgtgatggtctgagactctcttaggagcagagctctgccgcaatggccatgtg gggatccacacctggtctgaggggcaactgagtctgcgggagaagagcggccctatgcatggtgtagatgccctgataaa gaacatctgtcctgtgaaagactcaatgagctgttatgttgtaaacaggaagcatttcacatccaaacgagaaaatcatg taaacatgtgtcttttctgtagagcataataaatggatgaggtttttgcaaaaaaaaaaaaaaaaaaaatgatagaccgt caataatttgttaaatgctttttaaaatgaatgctttaagccgggtgcagtgcctcacatctgtaatcccagcactttgg agccgagcgggtggattgtgtgaggtcaggagttcgagaccaacctggccaacatggcaaaacctcactctctaccaaaa atacaaaaattagccaggcatggtggcaggcacctgtgatcccagctactcaggaggctgagacaggagaatcgcttgaa cccgggaggcaaggttgcagtgagccaagattacgccattgtactccagcctgggtgacagagagagactccgtctcaaa aaaaaaaaaaaaaaaaaaaaaattacgcttcaaacacatgatctctcaccactgttgaattttctttctatgagcccagg agggcctctcagagaggaaagctcctaggtcttcctttccctctgcaaactccctgccttgaaggttcagaaggactgtg cgtgctcgttgcatcctttgcaagtgtccaaaccctgatcccagctgtgcttaggggttcctgcaaaccttttccaggtg ttaattacctcccacttcatttcctgtttaccaactcagctttttgttttagtgtgtttgaattccctgaactgaccgtt gtctgatctccacctcccaactgaattaggggagctgggcttctggaaacccaggtgccgggtgttgcagagtggctgaa agctgggatgtggcagatccgtggctacattcatgcacacacacacacccacatacccacacatgcacacacacacacac acccgcactcacacacttggacatgcatagaccacagctttccacacccttcctagacaggggtcacttggtatcctgga gagagtgtgaagtcctggaatggaaagaggggggattaagccccacctctagccatgggactgagacaagtcaccaccaa cccatctgcgccttgtttacctcctctgtgaggcaagcacagagcccatgcctgcccccctggatgggagtgatgtgaaa cttgaagggcggtcagagcaagggtcgggaatggaaggcccttgggaaaaaaggccctttcaactaggggcacagaggag gccctgggctgagaacttgacagcaccttgtaattggtaagccaagcccgaagggactggaaatactcagatgtgtctgt ctcccttattaggttcaaagtccctcaagaccctgtctccatcacagtgctccagtccagacccctcctctgagctccag accctgctggacccaaccagccctatggggtcgcatccccacctgcctggaattctccaaagaacctcccctttaacagt tccagcctttaacagttccagtctaaacacatgacctttctcctctaaatcagccccccatctctgcctttgcaggagat ggaagccatgacacctgcctcgcccctgtcctcaccccatccatgtccaatcaagcactaggcatgtcaggtttaccctc taaactcctctggaatccagtctctcagtctccatcatcccaggtcgaagctaatgggctaactggtccttgcttccact ctacccccactgcagtcctgacttcctgagcagcagccagggcctaatcgatattcacaccaagcgccaacctgactgag atatcctcctgcaccatcatccctccaccctgtttagttctgctcaccctcagtgttctcatcaataatccactcccctc acaggcgcgtttgggaccccatgttctatgctctcacaggaccttttgcttgatttttcactgtacttaggtcagtttgc agttattaagtgactgagcaatgtctggcttctccagtagactgtcagctcctagccattgtatacctagcaccgctgtg tgggagcacgtgacaaacgtccagtgagtcagggactcagcagtctccatttctccgccctgctggagaatgcgtgtatt tggcaatccccagcccctgtgccatctaaccatcttttcttctctgttcagcccaggtgtggcctcactcacatcccact ctgagtccaaatgttctctccctggaagatatcaatgtttctgtctgttcgtgaggactccgtgcccaccacggcctctt tcaggtgagtcaaagggattcctcagttcactagttaggggaggtgggcagacaccctggagaactccctggaaagctca actctcatgccccggacaacagttgaaggaaccatggtgatgttaagcccaaagacaaaacctctcaggtgtccaagtcc ctgttggaatcttgggagcagagggaatgttctgtggtctagaggaagaggggctcagggaggagaagggcacattcctg gttgttatatgtttctatctatcccagatgaacttggaagtgaagggaagagagttaaacattaaagtaaatacccagtg gatcagacagcaatgtgccagattgccttggaaacaaaatatctccaacacatggctgacatttggtgggagatcagaac accctaaagagagaatttaaggggagggggaggaggacctgagccagagtagaagcagaggatagggagatctgttcttg gggacagcatttgcaagaaacaaggctgaggggtccactccaacctctccaccctgctgcaggtgctgcctatgatgaag atgagcagatggccatctcagctggggccacagtgcactggacctatagtttccaattccgcactcagcaggcatctttc tgatgatccgatggcttctcagagccagggatgggccaggatccatccccttggctactgtcttgctgagaaatttataa gcagcatctggtgctatactttggtctctagtgagttagctcatgaaagatgatagactctccaagccaggggtatgcag gaaatgggttttctgtagctacagaaatggggttgagggttggaccaagggactacccaggggaagtcttaccttcagag gactctggaaaggaggctgcaagttttcatgggtcaagaattcagagcccagtagagacagcttatctctgttccaagat gtctggggccttggttggaagattcaaaggctaggaaaccaggagccaccaaaagcgtaactggggccagaggatccact ttcaaggtggcaagttggttccccccatgtggctgcttgagtatcctcacatggcggctcacatccttccaagtaagcaa tgcaaaaggccaagaaagatgctgcaaagatgttatgacctagcctcagaaatcacacaccatccctgccaccattagta agaagtccagcccacgtccaggagaagaggaagcagattcctccttttgaaatgaagaatatcaagtaattcggggggca tatgaaagccaccacacaccacagggatctttttagagcatacttcttataccatcactgtagttccttaagactcaggg gcaaagcctcacttccttagcacccagtgaagaccacgcttactccctcactcaacctcttgctacttcccacctctcct gtccaacatctagtgtcactttccagaacataccaacagcttccccagttctgtgcctctgctcaggctgttccccctgc ctggtccacttgtcctccttcttgtccggtcaaaatgcttcttatccttcaagacccagctctagagtcacctccaaccc cttacccaccagccccctctccaagtctgtgtcccacaacccccctgctccctccagggcaccctccaccctctgggcca cagttgtcaggagtcaggcagggcaggggccgggtggtgtcttctttgtgttcttgcactcagggcagagctcagcacag agcagacgctcaaaaaacatttaaaggatagaagcattgatttgtgggtcccccagtctggctccaggatgccagccagc tgctcctagaagcaaacggacttttcctgggaaatcccagaggtgatgatcagtaatctctcccgtgactcgtagttcag ctcttcctccatgagcctgactatcagtggaccttccagaaagagccccttttccttctctcacccacagcacagggcac tgggaaaatgcccaatgagtcctgcctctgggttgtgctttggacttttcagtgtgtctcgcatccactcttcaacttga atgttgcaacagccatgaaaaaagaaatgcaaagcgattcaggatgagagcaataccctactccaaagaaggcaacatag aagctcagagagatcaagcaatttgcccaagaccacacagctaggagtggaactcatggctgtccaagccccatgcctct gctgaaggtagagatgaattacagcaacaagtctagaaaggtgcctgccctatggtctgtgagtcttgcctaagaatgaa agaggagccagtgggttaaagatgaggtcaccaacaacggtggtgttggagtttaccactgataataagggtgcaaaatg taaattactaatgtttattgagcctagtgcagtgcgtggggcattttgcacattgtctctgatccctatgacaaccctga gaggtagtggttttaactgccatgttacaggtgaggtcattgtggttcaaggacgttaagtaacttccccagcgtgacac ggcttataagtaaggcagccaggatgtgaacccagtaggactatctggctgcaaagtccccacccccctcgccatctgta tcctccaatcacttcagtgctttgctgcatagaaggtaacggaaatcacgatgccacagactgtccaggaagacagaaac taggcagatgggctggccatggtctccaagccagactggaatctccaggtctggaatgatatcatttttctcttttaata aattaactcacccaccacacggctttgagaggctcaaagttgaccaactcccttgggagggccccggttgataaggaagg aacgtgaatcctcccatcacggaagcttcaaggaggtcaagggtccaacacttgagattgttagtgctgttggtggatac tggccaaggaaatatcccagtggagcctcgagatgaagaacatgaggcccccgtttagaaccaaggatcagagggggctc tgtaagacccaggggagtcaggtgcactggagcgcgggcatgcagaaaacagcctgagctccacctcggcttctccttgt cctggctggttgtccttaacccctgtctccttctggaccagtttttgtccttcccttgtgaccgctgaggggtaacagcc tctttccactttctttcagcgccgacatgctcaatgtcaccttgcaagggcccactcttaacgggacctttgcccagagc aaatgcccccaagtggagtggctgggctggctcaacaccatccagccccccttcctctgggtgctgttcgtgctggccac cctagagaacatctttgtcctcagcgtcttctgcctgcacaagagcagctgcacggtggcagagatctacctggggaacc tggccgcagcagacctgatcctggcctgcgggctgcccttctgggccatcaccatctccaacaacttcgactggctcttt ggggagacgctctgccgcgtggtgaatgccattatctccatgaacctgtacagcagcatctgtttcctgatgctggtgag catcgaccgctacctggccctggtgaaaaccatgtccatgggccggatgcgcggcgtgcgctgggccaagctctacagct tggtgatctgggggtgtacgctgctcctgagctcacccatgctggtgttccggaccatgaaggagtacagcgatgagggc cacaacgtcaccgcttgtgtcatcagctacccatccctcatctgggaagtgttcaccaacatgctcctgaatgtcgtggg cttcctgctgcccctgagtgtcatcaccttctgcacgatgcagatcatgcaggtgctgcggaacaacgagatgcagaagt tcaaggagatccagacggagaggagggccacggtgctagtcctggttgtgctgctgctattcatcatctgctggctgccc ttccagatcagcaccttcctggatacgctgcatcgcctcggcatcctctccagctgccaggacgagcgcatcatcgatgt aatcacacagatcgcctccttcatggcctacagcaacagctgcctcaacccactggtgtacgtgatcgtgggcaagcgct tccgaaagaagtcttgggaggtgtaccagggagtgtgccagaaagggggctgcaggtcagaacccattcagatggagaac tccatgggcacactgcggacctccatctccgtggaacgccagattcacaaactgcaggactgggcagggagcagacagtg agcaaacgccagcagggctgctgtgaatttgtgtaaggattgagggacagttgcttttcagcatgggcccaggaatgcca aggagacatctatgcacgaccttgggaaatgagttgatgtctccggtaaaacaccggagactaattcctgccctgcccaa ttttgcagggagcatggctgtgaggatggggtgaactcacgcacagccaaggactccaaaatcacaacagcattactgtt cttatttgctgccacacctgagccagcctgctccttcccaggagtggaggaggcctgggggcagggagaggagtgactga gcttccctcccgtgtgttctccgtccctgccccagcaagacaacttagatctccaggagaactgccatccagctttggtg caatggctgagtgcacaagtgagttgttgccctgggtttctttaatctattcagctagaactttgaaggacaatttcttg cattaataaaggttaagccctgaggggtccctgataacaacctggagaccaggattttatggctcccctcactgatggac aaggaggtctgtgccaaagaagaatccaataagcacatattgagcacttgctgtatatgcagtattgagcactgtaggca agagggaagaaagagaaggagccatctccatcttgaaggaactcaaagactcaagtgggaacgactgggcactgccacca ccagaaagctgttcgatgagacggtcgagcagggtgctgtgggtgatatggacagcagaagggggagccaggttccagct caccaatactattgcacaccacctgtcctgcctcctgcagaaaacagcctgagctccacctcggcttctccttgccctgg ctggttgtccttaacccctgtctccttctggaccagtttttgtccttcccttgtgaccctgaggggtaacagcctctttt ccactttctttcagcgccgacatgctcaatgtcaccttgcaagggcccactcttaacgggacctttgcccagagcaaatg cccccaagtggagtggctgggctggctcaacaccatccagccccccttcctctgggtgctgttcgtgctggccaccctag agaacatctttgtcctcagcgtcttctgcctgcacaagagcagctgcacggtggcagagatctacctggggaacctggcc gcagcagacctgatcctggcctgcgggctgcccttctgggccatcaccatctccaacaacttcgactggctctttgggga gacgctctgccgcgtggtgaatgccattatctccatgaacctgtacagcagcatctgtttcctgatgctggtgagcatcg accgctacctggccctggtgaaaaccatgtccatgggccggatgcgcggcgtgcgctgggccaagctctacagcttggtg atctgggggtgtacgctgctcctgagctcacccatgctggtgttccggaccatgaaggagtacagcgatgagggccacaa cgtcaccgcttgtgtcatcagctacccatccctcatctgggaagtgttcaccaacatgctcctgaatgtcgtgggcttcc tgctgcccctgagtgtcatcaccttctgcacgatgcagatcatgcaggtgctgcggaacaacgagatgcagaagttcaag gagatccagacggagaggagggccacggtgctagtcctggttgtgctgctgctattcatcatctgctggctgcccttcca gatcagcaccttcctggatacgctgcatcgcctcggcatcctctccagctgccaggacgagcgcatcatcgatgtaatca cacagatcgcctccttcatggcctacagcaacagctgcctcaacccactggtgtacgtgatcgtgggcaagcgcttccga aagaagtcttgggaggtgtaccagggagtgtgccagaaagggggctgcaggtcagaacccattcagatggagaactccat gggcacactgcggacctccatctccgtggaacgccagattcacaaactgcaggactgggcagggagcagacagtgagcaa acgccagcagggctgctgtgaatttgtgtaaggattgagggacagttgcttttcagcatgggcccaggaatgccaaggag acatctatgcacgaccttgggaaatgagttgatgtctccggtaaaacaccggagactaattcctgncctgcccaattttg cagggagcatggctgtgaggatggggtgaactcacgcacagccaaggactccaaaatcacaacagcattactgttcttat ttgctgccacacctgagccagcctgctccttcccaggagtggaggaggcctgggggcagggagaggagtgactgagcttc cctcccgtgtgttctccgtccctgccccagcaagacaacttagatctccaggagaactgccatccagctttggtgcaatg gctgagtgcacaagtgagttgttgccctgggtttctttaatctattcagctagaactttgaaggacaatttcttgcatta ataaaggttaagccctgaggggtccctgataacaacctggagaccaggattttatggctcccctcactgatggacaaggg aggtctgtgccaaagaagaatccaataagcacatattgagcacttgctgtatatgcagtattgagcactgtaggcaagag ggaagaaagagaaggagccatctccatcttgaaggaactcaaagactcaagtgggaacgactggcactgccaccaccaga aagctgttcgacgagacggtcgagcagggtgctgtgggtgatatggacagcagaagggggagaccaaggttccagctcaa ccaataactattgcacaaccacctgtccctgcctcagttccctcttctgtaacatgaagtcgttgtgagggttaaaggca gtaacaggtataaagtacttagaaaagcaaagggtgctacgtacatgtgaggcatcattacgcagacgtaactgggatat gtttactataaggaaaagacactgaggtctagatgatcctatcacaacctgagagtagtttttactccatttacaggtga ggtcattgtggttcaaggacgttaagtaacttccccagctcacacggcttataagtaaggcagccaggatgtgaacccag taggactatctggctgcaaagtccccaccctccctcgccatctgtatcctccaatcatcttcagtgctttgctgatagaa ggtacggaaatacgatgccacagactgtccaggaagacagaaactaggcagatgggctggccatggtctccaagccagac tggaatctccaggtctggaatgatatcatttttctcttttaataaattaactcacccaccacacggctttgagaggctca aaggtgaccaactcccttgggagggccccggttgataaggaaggaatgtgaatcctcccatcacggaagcttcaaggagg tcaagggtccaacacttgagattgttagtgctgttggtggatactgcagaatatccagtggagcctcagatgaagaacat gaggccccgtttagatccaaggatcagagggggctctgtaagacccaggggagtcaggtgcactggagcgcgggctgcag aaaacagcctgagctccacctcggcttctccttgccctggctggttgtccttaacccctgtctccttctggaccagtttt tgtccttcccttgtgacctgaggggtaacagcctcttttccactttctttcagcgccgacatgctcaatgtcaccttgca agggcccactcttaacgggacctttgcccagagcaaatgcccccaagtggagtggctgggctggctcaacaccatccagc cccccttcctctgggtgctgttcgtgctggccaccctagagaacatctttgtcctcagcgtcttctgcctgcacaagagc agctgcacggtggcagagatctacctggggaacctggccgcagcagacctgatcctggcctgcgggctgcccttctgggc catcaccatctccaacaacttcgactggctctttggggagacgctctgccgcgtggtgaatgccattatctccatgaacc tgtacagcagcatctgtttcctgatgctggtgagcatcgaccgctacctggccctggtgaaaaccatgtccatgggccgg atgcgcggcgtgcgctgggccaagctctacagcttggtgatctgggggtgtacgctgctcctgagctcacccatgctggt gttccggaccatgaaggagtacagcgatgagggccacaacgtcaccgcttgtgtcatcagctacccatccctcatctggg aagtgttcaccaacatgctcctgaatgtcgtgggcttcctgctgcccctgagtgtcatcaccttctgcacgatgcagatc atgcaggtgctgcggaacaacgagatgcagaagttcaaggagatccagacggagaggagggccacggtgctagtcctggt tgtgctgctgctattcatcatctgctggctgcccttccagatcagcaccttcctggatacgctgcatcgcctcggcatcc tctccagctgccaggacgagcgcatcatcgatgtaatcacacagatcgcctccttcatggcctacagcaacagctgcctc aacccactggtgtacgtgatcgtgggcaagcgcttccgaaagaagtcttgggaggtgtaccagggagtgtgccagaaagg gggctgcaggtcagaacccattcagatggagaactccatgggcacactgcggacctccatctccgtggaacgccagattc acaaactgcaggactgggcagggagcagacagtgagcaaacgccagcagggctgctgtgaatttgtgtaaggattgaggg acagttgcttttcagcatgggcccaggaatgccaaggagacatctatgcacgaccttgggaaatgagtgttgatgtctcc ggtaaaacaccggagactaattcctgccctgcccaattttcgagggagcatggctgtgaggatggggtgaactcacgcac agccaaggactccaaaatcacaacagcattactgttcttatttgctgccacacctgagccagcctgctccttcccaggag tggaggaggcctgggggagggagaggagtgactgagcttccctcccgtgtgttctccgtccctgccccagcaagacaact tagatctccaggagaactgccatccacgtttggtgcaatggctgagtgcacaagtgagttgttgccctgggtttctttaa tctatcagctagaactttgaaggacaatttcttgcattaataaaggttaagccctgaggggtcccttgataacaacctgg agaccaggattttatggctcccctcactgatggacaaggaggtctgtgccaaagaagaatcaataagcacatatgagcac ttctgtatatcagtattgagcactgtaggcaatgttctctccctggaagatatcaatgtttctgtctgtttgtgaggact ccgtgcccaccacggcctctttcagcgccgacatgctcaatgtcaccttgcaagggcccactcttaacgggacctttgcc cagagcaaatgcccccaagtggagtggctgggctggctcaacaccatccagccccccttcctctgggtgctgttcgtgct ggccaccctagagaacatctttgtcctcagcgtcttctgcctgcacaagagcagctgcacggtggcagagatctacctgg ggaacctggccgcagcagacctgatcctggcctgcgggctgcccttctgggccatcaccatctccaacaacttcgactgg ctctttggggagacgctctgccgcgtggtgaatgccattatctccatgaacctgtacagcagcatctgtttcctgatgct ggtgagcatcgaccgctacctggccctggtgaaaaccatgtccatgggccggatgcgcggcgtgcgctgggccaagctct acagcttggtgatctgggggtgtacgctgctcctgagctcacccatgctggtgttccggaccatgaaggagtacagcgat gagggccacaacgtcaccgcttgtgtcatcagctacccatccctcatctgggaagtgttcaccaacatgctcctgaatgt cgtgggcttcctgctgcccctgagtgtcatcaccttctgcacgatgcagatcatgcaggtgctgcggaacaacgagatgc agaagttcaaggagatccagacggagaggagggccacggtgctagtcctggttgtgctgctgctattcatcatctgctgg ctgcccttccagatcagcaccttcctggatacgctgcatcgcctcggcatcctctccagctgccaggacgagcgcatcat cgatgtaatcacacagatcgcctccttcatggcctacagcaacagctgcctcaacccactggtgtacgtgatcgtgggca agcgcttccgaaagaagtcttgggaggtgtaccagggagtgtgccagaaagggggctgcaggtcagaacccattcagatg gagaactccatgggcacactgcggacctccatctccgtggaacgccagattcacaaactgcaggactgggcagggagcag acagtgagcaaacgccagcagggctgctgtgaatttgtgtaaggattgagggacagttgcttatgttctctccctggaag atatcaatgtttctgtctgttcgtgaggactccgtgcccaccacggcctctttcagcgccgacatgctcaatgtcacctt gcaagggcccactcttaacgggacctttgcccagagcaaatgcccccaagtggagtggctgggctggctcaacaccatcc agccccccttcctctgggtgctgttcgtgctggccaccctagagaacatctttgtcctcagcgtcttctgcctgcacaag agcagctgcacggtggcagagatctacctggggaacctggccgcagcagacctgatcctggcctgcgggctgcccttctg ggccatcaccatctccaacaacttcgactggctctttggggagacgctctgccgcgtggtgaatgccattatctccatga acctgtacagcagcatctgtttcctgatgctggtgagcatcgaccgctacctggccctggtgaaaaccatgtccatgggc cggatgcgcggcgtgcgctgggccaagctctacagcttggtgatctgggggtgtacgctgctcctgagctcacccatgct ggtgttccggaccatgaaggagtacagcgatgagggccacaacgtcaccgcttgtgtcatcagctacccatccctcatct gggaagtgttcaccaacatgctcctgaatgtcgtgggcttcctgctgcccctgagtgtcatcaccttctgcacgatgcag atcatgcaggtgctgcggaacaacgagatgcagaagttcaaggagatccagacggagaggagggccacggtgctagtcct ggttgtgctgctgctat catcatctgctggctgcccttccagatcagcaccttcctggatacgctgcatcgcctcggca tcctctccagctgccaggacgagcgcatcatcgatgtaatcacacagatcgcctccttcatggcctacagcaacagctgc ctcaacccactggtgtacgtgatcgtgggcaagcgcttccgaaagaagtcttgggaggtgtaccagggagtgtgccagaa agggggctgcaggtcagaacccattcagatggagaactccatgggcacactgcggacctccatctccgtggaacgccaga ttcacaaactgcaggactgggcagggagcagacagtgagcaaacgccagcagggctgctgtgaatttgtgtaaggattga gggacagttgcttgcccttcaaagatgagctgttcccgccgccactccagctctggcttctgggctccgaggaggggtgg ggacggtggggacatcaggctgccccgcagtaccagggagcgactgaagtgcccatgccgcttgctccggagaaggtggg tgccgggcaggggctgctccagccgcctcacctctgctgggaggacaaactgtcccagcacagagggagggagggagggc aggcagcggggagaagtttccctgtggtcgtggggagttgcccttcaaagatgagctgttcccgccgccactccagctct ggcttctgggctccgaggaggggtggggacggtggtgacggtggggacatcaggctgccccgcagtaccagggagcgact gaagtgcccatgccgcttgctccggagaaggtgggtgccgggcaggggctgctccagccgcctcacctctgctgggagga caaactgtcccagcacagagggagggagggagggcaggcagcggggagaagtttccctgtggtcgtggggagttgagctc ttcaatattttagtgaaagctatagatgaggctccataggggataaagcacagacacaccttttcagagggcttgtggac tctgggcagcctgtccatagacctctgtccccaactggcaagtcaggaaactccagattaaggagccccaatgtggttga acagccaggtgcacagatgagtcaaccacacagccaggccagggagggccttcactcaagagcctacagccagttcacag ccaagccagggctagcgccaggccacccataaactgatctgagactctgtttccctgtctccatgatgatgggatcaggc ttgattgctggtttgtaggcttgttatgaatcaagtcacagggaagaggagctgatgggctggggggacgtcctctggcc ctcctgtctcttccccagatccactgggcccactcttatctgttctcttctgaaggaagggttttaaggcttcaaaaaaa aatgttttgaaagtccctgccctttccagctcctaccgtctcagccctgggagtgtaaagtgctgcagatagttagtaag tct tgagcaaaactgagaaagccagcctgagccttgacatgggagaaacctccgccatacatctccgaagaaacggccg cgtgtctcaggggagcgcaaacacccgtacccaggaaacaggacagcttctgccactgtcgcccttgggagccgtacgtg gcatgacaaagaaatcccaggactccgcctgcccacctggccaccctctgtttacaccttccgcgtaaacgcccactgtt tacatccaaaactcagacacaaaataaccacctcaagaagataaataatgataagaaataaatgttacgcgaggcaaatt tattcacatggggcttcccaggccactttgtggtcagccgggagggacgtttttgccgtcccacgactccaacgggcagc cgggcctacgcaaacatggaaatcttccaagagcctccctggcccccagggctcagagggtggcagagcggagagcgaag gtggccgcagccttcccggccccacagccagcctggctccagctgggcaggagtgcagagctcagctggaggcgaggggg aagtgcccaggaggctgatgacatcactacccagcccttcaaagatgagctgttcccgccgccactccagctctggcttc tgggctccgaggaggggtggggacggtggtgacggtggggacatcaggctgccccgcagtaccagggagcgactgaagtg cccatgccgcttgctccggagaaggtgggtgccgggcaggggctgctccagccgcctcacctctgctgggaggacaaact gtcccagcacagagggagggagggagggcaggcagcggggagaagtttccctgtggtcgtggggagttgggaaaagttcc cttccttccggagggaggcagattcacaaactgcaggactgggcagggagcagacagtgagcaaacgccagcagggctgc tgtgaatttgtgtaaggattgagggacagttgcttttcagcatgggcccaggaatgccaaggagacatctatgcacgacc ttgggaaatgagttgatgtctccggtaaaacaccggagactaattcctgccctgcccaattttgcagggagcatggctgt gaggatggggtgaactcacgcacagccaaggactccaaaatcacaacagcattactgttcttatttgctgccacacctga gccagcctgctccttcccaggagtggaggaggcctggggggagggagaggagtgactgagcttccctcccgtgtgttctc cgtccctgccccagcaagacaacttagatctccaggagaactgccatccagctttggtgcaatggctgagtgcacaagtg agttgttgccctgggtttctttaatctattcagctagaactttgaaggacaatttcttgcattaataaaggttaagccct gaggggtccctgataacaacctggagaccaggattttatggctcccctcactgatggacaaggaggtctgtgccaaagaa gaatccaataagcacatattgagcacttgctgtatatgcagtattgagcactgtaggcaagacccaagaaagagaaggag ccatctccatcttgaaggaactcaaagactcaagtgggaacgactgggcactgccaccaccagaaagctgttcgacgaga cggtcgagcagggtgctgtgggtgatatggacagcagaagggggagaccaaggttccagctcaaccaataactattgcac aaccacctgtccctgcctcagttcccttttatgtaacatgaagtcgttgtgagggttaaaggcagtaacaggtataaagt 5 acttagaaaagcaaagggtgctacgtacatgtgaggcatcattacgcagacgtaactgggatatgtttactataaggaaa agacactgaggtctagaaatagctccgtggagcagaatcagtattgggagccggtggcggtgtgaagcaccagtgtctgg cacacagtaggtgctcattggctcccttccacctgtcattcccaccaccctgaggccccaaccgccacacacacaggagc atttggagagaaggccatgtcttcaaagtctgatttgtgatgaggcagaggaagatatttctaatcggtcttgcccagag gatcacagtgctgagaccccccaccaccagccggtacctgggaagggggagagtgcaggcctgctcagggactgttcctg

10 tctcagcaaccaagggattgttcctgtcaatcaatggtttattggaaggtggcccagtatgagccctagaagagtgtgaa aaggaatggcaatggtgttcaccatcggcagtgccagggcagcactcattcacttgataaatgaatatttattagctggt tggagagctagaacctggagagctagaacctggagaactagaacctggagggctagaacctggagaggctagaaccaaga agggctagaacctggaggggctagaacctagagaagctaaaacctgagctagaagctggaggactagaacctggagggct ggaatctgaagggctagaacctggagggctggaatctggagagctagaacctggagggctagaacctggagggctagaac

15 ctagaagggctagaacctggagggctggaatctggagagctagaacctggagggctagaacctggagggctagaacctag aagggctagaacctggagggctagaacctggcaggttagaacctagaagggctagaacctggagagccagaacctggagg gctagaacctggaagggctagaacctgtagagctagaacatggagagctagaacccggcaggctagaacctggcaagcta gaacctggagggaatgaacctggagggctagaacctggagaatgagaaaaatttacatggcaaagagcccataaatcctg accaatccaactctgaattttaaagcaaaagcgtgaaaaaaaagattccctccttacccccaacccactcttttttccca

20 ccacccactctcctctgcctcagtaagtatctggaggaagaaaacaggtgaaagaagaagtaaaaaccatttagtattag tattagaatgaagtcaaactgtgccacacatggtgaatgaaaaaaaaaaaaaagaggctgtgttttgtcacacagggcag tcattcagcaccagagcacgtgatggtctgagactctcttaggagcagagctctgccgcaatggccatgtggggatccac acctggtctgaggggcaactgagtctgcgggagaagagcggccctatgcatggtgtagatgccctgataaagaacatctg tcctgtgaaagactcaatgagctgttatgttgtaaacaggaagcatttcacatccaaacgagaaaatcatgtaaacatgt

25 gtcttttctgtagagcataataaatggatgaggtttttgcaaaaaaaaaaaaaaaaaaaatgatagaccgtcaataattt gttaaatgctttttaaaatgaatgctttaagccgggtgcagtgcctcacatctgtaatcccagcactttggagccgagcg ggtggattgtgtgaggtcaggagttcgagaccaacctggccaacatggcaaaacctcactctctaccaaaaatacaaaaa ttagccaggcatggtggcaggcacctgtgatcccagctactcaggaggctgagacaggagaatcgcttgaacccgggagg caaggttgcagtgagccaagattacgccattgtactccagcctgggtgacagagagagactccgtctcaaaaaaaaaaaa

30 aaaaaaaaaaaaattacgcttcaaacacatgatctctcaccactgttgaattttctttctatgagcccaggagggcctct cagagaggaaagctcctaggtcttcctttccctctgcaaactccctgccttgaaggttcagaaggactgtgcgtgctcgt tgcatcctttgcaagtgtccaaaccctgatcccagctgtgcttaggggttcctgcaaaccttttccaggtgttaattacc tcccacttcatttcctgtttaccaactcagctttttgttttagtgtgtttgaattccctgaactgaccgttgtctgatct ccacctcccaactgaattaggggagctgggcttctggaaacccaggtgccgggtgttgcagagtggctgaaagctgggat

35 gtggcagatccgtggctacattcatgcacacacacacacccacatacccacacatgcacacacacacacacacccgcact cacacacttggacatgcatagaccacagctttccacacccttcctagacaggggtcacttggtatcctggagagagtgtg aagtcctggaatggaaagaggggggattaagccccacctctagccatgggactgagacaagtcaccaccaacccatctgc gccttgtttacctcctctgtgaggcaagcacagagcccatgcctgcccccctggatgggagtgatgtgaaacttgaaggg cggtcagagcaagggtcgggaatggaaggcccttgggaaaaaaggccctttcaactaggggcacagaggaggccctgggc

40 tgagaacttgacagcaccttgtaattggtaagccaagcccgaagggactggaaatactcagatgtgtctgtctcccttat taggttcaaagtccctcaagaccctgtctccatcacagtgctccagtccagacccctcctctgagctccagaccctgctg gacccaaccagccctatggggtcgcatccccacctgcctggaattctccaaagaacctcccctttaacagttccagcctt taacagttccagtctaaacacatgacctttctcctctaaatcagccccccatctctgcctttgcaggagatggaagccat gacacctgcctcgcccctgtcctcaccccatccatgtccaatcaagcactaggcatgtcaggtttaccctctaaactcct

45 ctggaatccagtctctcagtctcca catcccaggtcgaagctaatgggctaactggtccttgcttccactctaccccca ctgcagtcctgacttcctgagcagcagccagggcctaatcgatattcacaccaagcgccaacctgactgagat tcctcc tgcaccatcatccctccaccctgtttagttctgctcaccctcagtgttctcatcaataatccactcccctcacaggcgcg tttgggaccccatgttctatgctctcacaggaccttttgcttgatttttcactgtacttaggtcagtttgcagttattaa gtgactgagcaatgtctggcttctccagtagactgtcagctcctagccattgtatacctagcaccgctgtgtgggagcac

50 gtgacaaacgtccagtgagtcagggactcagcagtctccatttctccgccctgctggagaatgcgtgtatttggcaatcc ccagcccctgtgccatctaaccatcttttcttctctgttcagcccaggtgtggcctcactcacatcccactctgagtcca aatgttctctccctggaagatatcaatgtttctgtctgttcgtgaggactccgtgcccaccacggcctctttcaggtgag tcaaagggattcctcagttcactagttaggggaggtgggcagacaccctggagaactccctggaaagctcaactctcatg ccccggacaacagttgaaggaaccatggtgatgttaagcccaaagacaaaacctctcaggtgtccaagtccctgttggaa

55 tcttgggagcagagggaatgttctgtggtctagaggaagaggggctcagggaggagaagggcacattcctggttgttata tgtttctatctatcccagatgaacttggaagtgaagggaagagagttaaacattaaagtaaatacccagtggatcagaca gcaatgtgccagattgccttggaaacaaaatatctccaacacatggctgacatttggtgggagatcagaacaccctaaag agagaatttaaggggagggggaggaggacctgagccagagtagaagcagaggatagggagatctgttcttggggacagca tttgcaagaaacaaggctgaggggtccactccaacctctccaccctgctgcaggtgctgcctatgatgaagatgagcaga

60 tggccatctcagctggggccacagtgcactggacctatagtttccaattccgcactcagcaggcatctttctgatgatcc gatggcttctcagagccagggatgggccaggatccatccccttggctactgtcttgctgagaaatttataagcagcatct ggtgctatactttggtctctagtgagttagctcatgaaagatgatagactctccaagccaggggtatgcaggaaatgggt tttctgtagctacagaaatggggttgagggttggaccaagggactacccaggggaagtcttaccttcagaggactctgga aaggaggctgcaagttttcatgggtcaagaattcagagcccagtagagacagcttatctctgttccaagatgtctggggc

65 cttggttggaagattcaaaggctaggaaaccaggagccaccaaaagcgtaactggggccagaggatccactttcaaggtg gcaagttggttccccccatgtggctgcttgagtatcctcacatggcggctcacatccttccaagtaagcaatgcaaaagg ccaagaaagatgctgcaaagatgttatgacctagcctcagaaatcacacaccatccctgccaccattagtaagaagtcca gcccacgtccaggagaagaggaagcagattcctccttttgaaatgaagaatatcaagtaattcggggggcatatgaaagc caccacacaccacagggatctttttagagcatacttcttataccatcactgtagttccttaagactcaggggcaaagcct

70 cacttccttagcacccagtgaagaccacgcttactccctcactcaacctcttgctacttcccacctctcctgtccaacat ctagtgtcactttccagaacataccaacagcttccccagttctgtgcctctgctcaggctgttccccctgcctggtccac ttgtcctccttcttgtccggtcaaaatgcttcttatccttcaagacccagctctagagtcacctccaaccccttacccac cagccccctctccaagtctgtgtcccacaacccccctgctccctccagggcaccctccaccctctgggccacagttgtca ggagtcaggcagggcaggggccgggtggtgtcttctttgtgttcttgcactcagggcagagctcagcacagagcagacgc

75. tcaaaaaacatttaaaggatagaagcattgatttgtgggtcccccagtctggctccaggatgccagccagctgctcctag aagcaaacggacttttcctgggaaatcccagaggtgatgatcagtaatctctcccgtgactcgtagttcagctcttcctc catgagcctgactatcagtggaccttccagaaagagccccttttccttctctcacccacagcacagggcactgggaaaat gcccaatgagtcctgcctctgggttgtgctttggacttttcagtgtgtctcgcatccactcttcaacttgaatgttgcaa cagccatgaaaaaagaaatgcaaagcgattcaggatgagagcaataccctactccaaagaaggcaacatagaagctcaga

80 gagatcaagcaatttgcccaagaccacacagctaggagtggaactcatggctgtccaagccccatgcctctgctgaaggt agagatgaattacagcaacaagtctagaaaggtgcctgccctatggtctgtgagtcttgcctaagaatgaaagaggagcc agtgggttaaagatgaggtcaccaacaacggtggtgttggagtttaccactgataataagggtgcaaaatgtaaattact aatgtttattgagcctagtgcagtgcgtggggcattttgcacattgtctctgatccctatgacaaccctgagaggtagtg gttttaactgccatgttacaggtgaggtcattgtggttcaaggacgttaagtaacttccccagcgtgacacggcttataa gtaaggcagccaggatgtgaacccagtaggactatctggctgcaaagtccccacccccctcgccatctgtatcctccaat cacttcagtgctttgctgcatagaaggtaacggaaatcacgatgccacagactgtccaggaagacagaaactaggcagat gggctggccatggtctccaagccagactggaatctccaggtctggaatgatatcatttttctcttttaataaattaactc acccaccacacggctttgagaggctcaaagttgaccaactcccttgggagggccccggttgataaggaaggaacgtgaat cctcccatcacggaagcttcaaggaggtcaagggtccaacacttgagattgttagtgctgttggtggatactggccaagg aaatatcccagtggagcctcgagatgaagaacatgaggcccccgtttagaaccaaggatcagagggggctctgtaagacc caggggagtcaggtgcactggagcgcgggcatgcagaaaacagcctgagctccacctcggcttctccttgtcctggctgg ttgtccttaacccctgtctccttctggaccagtttttgtccttcccttgtgaccgctgaggggtaacagcctctttccac tttctttcagcgccgacatgctcaatgtcaccttgcaagggcccactcttaacgggacctttgcccagagcaaatgcccc caagtggagtggctgggctggctcaacaccatccagccccccttcctctgggtgctgttcgtgctggccaccctagagaa catctttgtcctcagcgtcttctgcctgcacaagagcagctgcacggtggcagagatctacctggggaacctggccgcag cagacctgatcctggcctgcgggctgcccttctgggccatcaccatctccaacaacttcgactggctctttggggagacg ctctgccgcgtggtgaatgccattatctccatgaacctgtacagcagcatctgtttcctgatgctggtgagcatcgaccg ctacctggccctggtgaaaaccatgtccatgggccggatgcgcggcgtgcgctgggccaagctctacagcttggtgatct gggggtgtacgctgctcctgagctcacccatgctggtgttccggaccatgaaggagtacagcgatgagggccacaacgtc accgcttgtgtcatcagctacccatccctcatctgggaagtgttcaccaacatgctcctgaatgtcgtgggcttcctgct gcccctgagtgtcatcaccttctgcacgatgcagatcatgcaggtgctgcggaacaacgagatgcagaagttcaaggaga tccagacggagaggagggccacggtgctagtcctggttgtgctgctgctattcatcatctgctggctgcccttccagatc agcaccttcctggatacgctgcatcgcctcggcatcctctccagctgccaggacgagcgcatcatcgatgtaatcacaca gatcgcctccttcatggcctacagcaacagctgcctcaacccactggtgtacgtgatcgtgggcaagcgcttccgaaaga agtcttgggaggtgtaccagggagtgtgccagaaagggggctgcaggtcagaacccattcagatggagaactccatgggc acactgcggacctccatctccgtggaacgccagattcacaaactgcaggactgggcagggagcagacagtgagcaaacgc cagcagggctgctgtgaatttgtgtaaggattgagggacagttgcttttcagcatgggcccaggaatgccaaggagacat ctatgcacgaccttgggaaatgagttgatgtctccggtaaaacaccggagactaattcctgccctgcccaattttgcagg gagcatggctgtgaggatggggtgaactcacgcacagccaaggactccaaaatcacaacagcattactgttcttatttgc tgccacacctgagccagcctgctccttcccaggagtggaggaggcctgggggcagggagaggagtgactgagcttccctc ccgtgtgttctccgtccctgccccagcaagacaacttagatctccaggagaactgccatccagctttggtgcaatggctg agtgcacaagtgagttgttgccctgggtttctttaatctattcagctagaactttgaaggacaatttcttgcattaataa aggttaagccctgaggggtccctgataacaacctggagaccaggattttatggctcccctcactgatggacaaggaggtc tgtgccaaagaagaatccaataagcacatattgagcacttgctgtatatgcagtattgagcactgtaggcaagagggaag aaagagaaggagccatctccatcttgaaggaactcaaagactcaagtgggaacgactgggcactgccaccaccagaaagc tgttcgatgagacggtcgagcagggtgctgtgggtgatatggacagcagaagggggagccaggttccagctcaccaatac tattgcacaccacctgtcctgcctctgatcctatcacaacctgagagtagtttttactccatttacaggtgaggtcattg tggttcaaggacgttaagtaacttccccagctcacacggcttataagtaaggcagccaggatgtgaacccagtaggacta tctggctgcaaagtccccaccctccctcgccatctgtatcctccaatcatcttcagtgctttgctgatagaaggtacgga aatacgatgccacagactgtccaggaagacagaaactaggcagatgggctggccatggtctccaagccagactggaatct ccaggtctggaatgatatcatttttctcttttaataaattaactcacccaccacacggctttgagaggctcaaaggtgac caactcccttgggagggccccggttgataaggaaggaatgtgaatcctcccatcacggaagcttcaaggaggtcaagggt ccaacacttgagattgttagtgctgttggtggatactgcagaatatccagtggagcctcagatgaagaacatgaggcccc gtttagatccaaggatcagagggggctctgtaagacccaggggagtcaggtgcactggagcgcgggctgcagaaaacagc ctgagctccacctcggcttctccttgccctggctggttgtccttaacccctgtctccttctggaccagtttttgtccttc ccttgtgacctgaggggtaacagcctcttttccactttctttcagcgccgacatgctcaatgtcaccttgcaagggccca ctcttaacgggacctttgcccagagcaaatgcccccaagtggagtggctgggctggctcaacaccatccagccccccttc ctctgggtgctgttcgtgctggccaccctagagaacatctttgtcctcagcgtcttctgcctgcacaagagcagctgcac ggtggcagagatctacctggggaacctggccgcagcagacctgatcctggcctgcgggctgcccttctgggccatcacca tctccaacaacttcgactggctctttggggagacgctctgccgcgtggtgaatgccattatctccatgaacctgtacagc agcatctgtttcctgatgctggtgagcatcgaccgctacctggccctggtgaaaaccatgtccatgggccggatgcgcgg cgtgcgctgggccaagctctacagcttggtgatctgggggtgtacgctgctcctgagctcacccatgctggtgttccgga ccatgaaggagtacagcgatgagggccacaacgtcaccgcttgtgtcatcagctacccatccctcatctgggaagtgttc accaacatgctcctgaatgtcgtgggcttcctgctgcccctgagtgtcatcaccttctgcacgatgcagatcatgcaggt gctgcggaacaacgagatgcagaagttcaaggagatccagacggagaggagggccacggtgctagtcctggttgtgctgc tgctattcatcatctgctggctgcccttccagatcagcaccttcctggatacgctgcatcgcctcggcatcctctccagc tgccaggacgagcgcatcatcgatgtaatcacacagatcgcctccttcatggcctacagcaacagctgcctcaacccact ggtgtacgtgatcgtgggcaagcgcttccgaaagaagtcttgggaggtgtaccagggagtgtgccagaaagggggctgca ggtcagaacccattcagatggagaactccatgggcacactgcggacctccatctccgtggaacgccagattcacaaactg caggactgggcagggagcagacagtgagcaaacgccagcagggctgctgtgaatttgtgtaaggattgagggacagttgc ttttcagcatgggcccaggaatgccaaggagacatctatgcacgaccttgggaaatgagtgttgatgtctccggtaaaac accggagactaattcctgccctgcccaattttcgagggagcatggctgtgaggatggggtgaactcacgcacagccaagg actccaaaatcacaacagcattactgttcttatttgctgccacacctgagccagcctgctccttcccaggagtggaggag gcctgggggagggagaggagtgactgagcttccctcccgtgtgttctccgtccctgccccagcaagacaacttagatctc caggagaactgccatccacgtttggtgcaatggctgagtgcacaagtgagttgttgccctgggtttctttaatctatcag ctagaactttgaaggacaatttcttgcattaataaaggttaagccctgaggggtcccttgataacaacctggagaccagg attttatggctcccctcactgatggacaaggaggtctgtgccaaagaagaatcaataagcacatatgagcacttctgtat atcagtattgagcactgtaggcaatgttctctccctggaagatatcaatgtttctgtctgtttgtgaggactccgtgccc accacggcctctttcagcgccgacatgctcaatgtcaccttgcaagggcccactcttaacgggacctttgcccagagcaa atgcccccaagtggagtggctgggctggctcaacaccatccagccccccttcctctgggtgctgttcgtgctggccaccc tagagaacatctttgtcctcagcgtcttctgcctgcacaagagcagctgcacggtggcagagatctacctggggaacctg gccgcagcagacctgatcctggcctgcgggctgcccttctgggccatcaccatctccaacaacttcgactggctctttgg ggagacgctctgccgcgtggtgaatgccattatctccatgaacctgtacagcagcatctgtttcctgatgctggtgagca tcgaccgctacctggccctggtgaaaaccatgtccatgggccggatgcgcggcgtgcgctgggccaagctctacagcttg gtgatctgggggtgtacgctgctcctgagctcacccatgctggtgttccggaccatgaaggagtacagcgatgagggcca caacgtcaccgcttgtgtcatcagctacccatccctcatctgggaagtgttcaccaacatgctcctgaatgtcgtgggct tcctgctgcccctgagtgtcatcaccttctgcacgatgcagatcatgcaggtgctgcggaacaacgagatgcagaagttc aaggagatccagacggagaggagggccacggtgctagtcctggttgtgctgctgctattcatcatctgctggctgccctt ccagatcagcaccttcctggatacgctgcatcgcctcggcatcctctccagctgccaggacgagcgcatcatcgatgtaa tcacacagatcgcctccttcatggcctacagcaacagctgcctcaacccactggtgtacgtgatcgtgggcaagcgcttc cgaaagaagtcttgggaggtgtaccagggagtgtgccagaaagggggctgcaggtcagaacccattcagatggagaactc catgggcacactgcggacctccatctccgtggaacgccagattcacaaactgcaggactgggcagggagcagacagtgag caaacgccagcagggctgctgtgaatttgtgtaaggattgagggacagttgcttatgttctctccctggaagatatcaat gtttctgtctgttcgtgaggactccgtgcccaccacggcctctttcagcgccgacatgctcaatgtcaccttgcaagggc ccactcttaacgggacctttgcccagagcaaatgcccccaagtggagtggctgggctggctcaacaccatccagcccccc ttcctctgggtgctgttcgtgctggccaccctagagaacatctttgtcctcagcgtcttctgcctgcacaagagcagctg cacggtggcagagatctacctggggaacctggccgcagcagacctgatcctggcctgcgggctgcccttctgggccatca ccatctccaacaacttcgactggctctttggggagacgctctgccgcgtggtgaatgccattatctccatgaacctgtac agcagcatctgtttcctgatgctggtgagcatcgaccgctacctggccctggtgaaaaccatgtccatgggccggatgcg cggcgtgcgctgggccaagctctacagcttggtgatctgggggtgtacgctgctcctgagctcacccatgctggtgttcc ggaccatgaaggagtacagcgatgagggccacaacgtcaccgcttgtgtcatcagctacccatccctcatctgggaagtg ttcaccaacatgctcctgaatgtcgtgggcttcctgctgcccctgagtgtcatcaccttctgcacgatgcagatcatgca ggtgctgcggaacaacgagatgcagaagttcaaggagatccagacggagaggagggccacggtgctagtcctggttgtgc tgctgctattcatcatctgctggctgcccttccagatcagcaccttcctggatacgctgcatcgcctcggcatcctctcc agctgccaggacgagcgcatcatcgatgtaatcacacagatcgcctccttcatggcctacagcaacagctgcctcaaccc actggtgtacgtgatcgtgggcaagcgcttccgaaagaagtcttgggaggtgtaccagggagtgtgccagaaagggggct gcaggtcagaacccattcagatggagaactccatgggcacactgcggacctccatctccgtggaacgccagattcacaaa ctgcaggactgggcagggagcagacagtgagcaaacgccagcagggctgctgtgaatttgtgtaaggattgagggacagt tgcttgcccttcaaagatgagctgttcccgccgccactccagctctggcttctgggctccgaggaggggtggggacggtg gggacatcaggctgccccgcagtaccagggagcgactgaagtgcccatgccgcttgctccggagaaggtgggtgccgggc aggggctgctccagccgcctcacctctgctgggaggacaaactgtcccagcacagagggagggagggagggcaggcagcg gggagaagtttccctgtggtcgtggggagttgcccttcaaagatgagctgttcccgccgccactccagctctggcttctg ggctccgaggaggggtggggacggtggtgacggtggggacatcaggctgccccgcagtaccagggagcgactgaagtgcc catgccgcttgctccggagaaggtgggtgccgggcaggggctgctccagccgcctcacctctgctgggaggacaaactgt cccagcacagagggagggagggagggcaggcagcggggagaagtttccctgtggtcgtggggagttgagctcttcaatat tttagtgaaagctatagatgaggctccataggggataaagcacagacacaccttttcagagggcttgtggactctgggca gcctgtccatagacctctgtccccaactggcaagtcaggaaactccagattaaggagccccaatgtggttgaacagccag gtgcacagatgagtcaaccacacagccaggccagggagggccttcactcaagagcctacagccagttcacagccaagcca gggctagcgccaggccacccataaactgatctgagactctgtttccctgtctccatgatgatgggatcaggcttgattgc tggtttgtaggcttgttatgaatcaagtcacagggaagaggagctgatgggctggggggacgtcctctggccctcctgtc tcttccccagatccactgggcccactcttatctgttctcttctgaaggaagggttttaaggcttcaaaaaaaaatgtttt gaaagtccctgccctttccagctcctaccgtctcagccctgggagtgtaaagtgctgcagatagttagtaagtctttgag caaaactgagaaagccagcctgagccttgacatgggagaaacctccgccatacatctccgaagaaacggccgcgtgtctc aggggagcgcaaacacccgtacccaggaaacaggacagcttctgccactgtcgcccttgggagccgtacgtggcatgaca aagaaatcccaggactccgcctgcccacctggccaccctctgtttacaccttccgcgtaaacgcccactgtttacatcca aaactcagacacaaaataaccacctcaagaagataaataatgataagaaataaatgttacgcgaggcaaatttattcaca tggggcttcccaggccactttgtggtcagccgggagggacgtttttgccgtcccacgactccaacgggcagccgggccta cgcaaacatggaaatcttccaagagcctccctggcccccagggctcagagggtggcagagcggagagcgaaggtggccgc agccttcccggccccacagccagcctggctccagctgggcaggagtgcagagctcagctggaggcgagggggaagtgccc aggaggctgatgacatcactacccagcccttcaaagatgagctgttcccgccgccactccagctctggcttctgggctcc gaggaggggtggggacggtggtgacggtggggacatcaggctgccccgcagtaccagggagcgactgaagtgcccatgcc gcttgctccggagaaggtgggtgccgggcaggggctgctccagccgcctcacctctgctgggaggacaaactgtcccagc acagagggagggagggagggcaggcagcggggagaagtttccctgtggtcgtggggagtt (SEQ ID NO: 12387) cccggccccgccbcgbbcc (SEQ ID Nθ:12414) cccggccccgccbcg (SEQ ID NO: 12415) cccggccccgccbcg (SEQ ID NO: 12431) tccbtgccbcgggcc (SEQ ID NO: 12434) tbbtcctbbcbcctgg (SEQ ID NO: 12447) gtgcbccbctcbcctg (SEQ ID NO: 12452) gggttbbbgttgbtctgg (SEQ ID NO: 12461) cctgggtgggctt (SEQ ID NO: 12467) cccavgvccvcccaggc (SEQ ID NO:12472) agcccacccaggc (SEQ ID NO: 12473) bcctgggtgggctb (SEQ ID NO: 12474) ggtgggcttggg (SEQ ID NO: 12475) ccbbggtgggcttggg (SEQ ID NO: 12476) ctgggtgggbbtggg (SEQ ID NO: 12477) ccbgggtgggcttgg (SEQ ID NO: 12478) gggtgggcttgg (SEQ ID NO : 12479) cctgbgtgbgcbtggg (SEQ ID NO : 12480 )

Table : Exemplary Genes and oligos

SEQ ID NOS. of oligos

SEQ ID NOS. (No. of Oligonucleotide GENEBANK ACCESSION NOS.

HUMAN GENES Nucleic acid (amino acid) Fragments) For the Genes

H2A histone family, member N 3285 3286-3364 (79) AI095013 tubulin, beta polypeptide 3365 3366-3405 (40) AI672565

ELL gene (11-19 lysine- rich leukemia gene) 3406 3407-3509(103) AI652901

7-dehydrocholesterol reductase 3510 3511-3592(82) AI652764 karyopherin alpha 2

(RAG cohort 1 , importin alpha 1 ) 3593 3594-3680 (87) AA489087

ADP-ribosylation factorlike 7 3681 3682-3709 (28) AA281534

EST 3710 3711-3740 (30) AI038433

EST 3741 3742-3808 (67) Al 122689 EST 3809 3810-3862 (53) AI092623

ESTs 3863 3864-3936 (73) AI095492

ESTs 3937 3938-3990 (53) AH 38216

ESTs 3991 3992-4059 (68) AH 28305

ESTs 4060 4061-4123 (63) AH 25228

ESTs 4124 4125-4181 (57) AI041482

ESTs 4182 4183-4258 (76) AI051839

Homo sapiens mRNA; cDNA DKFZp434A1716

(from clone

DKFZp434A1716) 4259 4260-4328 (69) AI092429

ESTs 4329 4330-4362 (33) AI096522

ESTs 4363 4364-4421 (58) AH 22807

ESTs 4422 4423-4483 (61) AI041212

EST 4484 4485-4544 (60) AI125651 enolase 1 , (alpha) 4545 4546-4629 (84) AI001174

EST 4630 4631-4683 (53) AI024215

EST 4684 4685-4729 (45) AI034360

Homo sapiens mRNA; cDNA DKFZp564H0764

(from clone

DKFZp564H0764) 4730 4731-4788 (58) AA465687

Homo sapiens mRNA for

KIAA1363 protein, partial eds 4789 4790-4853 (64) AI085559 potassium voltage-gated channel, shaker-related subfamily, beta member

2 4854 4855-4920 (66) AI654215

ER-associated DNAJ;

ER-associated Hsp40 co-chaperone; hDj9;

ERj3 4921 4922-4948 (27) AA505075

ESTs, Weakly similar to p38 protein [H.sapiens] 4949 4950-5008 (59) AA906703

CGI-142 5009 5010-5084 (75) AI369870

ESTs 5085 5086-5138 (53) AA463249

Homo sapiens clone

25058 mRNA sequence 5139 5140-5165 (26) R38894

ESTs 5166 5167-5203 (37) R49144 squamous cell carcinoma antigen 1 5204 5205-5290 (86) AA398883

ESTs 5291 5292-5349 (58) AA425700 myosin X 9 (10) 1628-2922 (1295) NM_012334, AA187977

ESTs 5350 5351-5395 (45) AA459692 epithelial protein lost in neoplasm beta 5396 5397-5453 (57) AA487557

CD44 antigen (homing function and Indian blood group system) 5454 5455-5509 (55) T69168 coagulation factor III

(thromboplastin, tissue factor) 5510 5511-5588 (78) AI313387

ESTs 5589 5590-5646 (57) AA909635 adducin 1 (alpha) 5647 5648-5705 (58) R00103

5' nucleotidase (CD73) 5706 5707-5767 (61) N35316

ESTs, Moderately similar to semaphorin C

[M.musculus] 5768 5769-5823 (55) AA293300

ESTs 5824 5825-5892 (68) AA278764

ESTs 5893 5894-5926 (33) AA678160 calmodulin 2

(phosphorylase kinase, delta) 11 (12) 2923-3107 (185) NM_001743, AA663941 ESTs 5927 5928-5996 (69) R42770 high-mobility group

(nonhistone chromosomal) protein 17 5997 5998-6095 (98) H93087 chloride intracellular channel 1 6096 6097-6177 (81 ) AA486518 ubiquitin carrier protein 6178 6179-6208 (30) AA464729 transglutaminase 2 (C polypeptide, protein- glutamine-gamma- glutamyltransferase) 1 (2) 13-552 (540) M55153, R97066 tubulin, alpha 1 (testis specific) 6209 6210-6270 (61 ) AA180912 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 6271 6272-6343 (72) AA436142 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 6344 6345-6413 (69) H05893 tubulin, beta polypeptide 6415-6485 (71) H37989 filamin B, beta (actin- binding protein-278) 6486 6487-6551 (65) AA486238 stanniocalcin 5 (6) 677-1323 (647) NM_003155, AA08531Σ low density lipoprotein receptor (familial hypercholesterolemia) 6552 6553-6609 (57) AA504461 plectin 1 , intermediate filament binding protein,

500kD 6610 6611-6683 (73) AA448400

S100 calcium-binding protein A2 3 (4) 553-676 (124) BC002829, AA458884 immediate early response 3 6684 6685-6735 (51) AA480815 calpain, large polypeptide L2 6736 6737-6831 (95) AA102454 pleckstrin homology-like domain, family A, member 1 6832 6833-6900 (68) AA258396 melanoma adhesion molecule 6901 6902-6979 (78) AA497002

CD44 antigen (homing function and Indian blood group system) 6980 6981-7069 (89) AA282906 programmed cell death 5 7070 7071-7159 (89) AA156940 hexokinase 1 7160 7161-7209 (49) AA485272 vascular endothelial growth factor 7210 7211-7290 (80) R19956 integrin, alpha 2

(CD49B, alpha 2 subunit of VLA-2 receptor) 7291 7292-7396 (105) AA463610 calumenin 7397 7398-7471 (74) R78585 syntaxin 11 7472 7473-7526 (54) R33851 diphtheria toxin receptor

(heparin-binding epidermal growth factorlike growth factor) 7527 7528-7578 (51 ) R14663

Fn14 for type I fransmenmbrane protein 7579 7580-7632 (53) R33355

Nef-associated factor 1 7633 7634-7694 (61 ) T64626 high-mobility group

(nonhistone chromosomal) protein isoforms I and Y 7695 7696-7753 (58) AA448261 catechol-O- methyltransferase 7754 7755-7796 (42) R44202

C-terminal binding protein 1 7797 7798-7864 (67) W81570 collagen, type XVII, alpha 1 7865 7866-7932 (67) AA128561

ESTs 7933 7934-8029 (96) N58473 farnesyl-diphosphate famesyltransferase 1 8030 8031-8107 (77) AA679352

RNA helicase-related protein 8108 8109-8147 (39) N55459 interferon stimulated gene (20kD) 8148 8149-8230 (82) AA150500 steroid-5-alpha- reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4- dehydrogenase alpha 1) 8231 8232-8283 (52) H 16833 prostaglandin- endoperoxide synthase 2

(prostaglandin G/H synthase and cyclooxygenase) 8284 8285-8345 (61 ) AA644211 laminin, alpha 3 (nicein

(150kD), kalinin (165kD),

BM600 (150kD), epilegrin) 8346 8347-8440 (94) AA001432 collagen, type XVII, alpha 1 8441 8442-8494 (53) H87536 keratin 18 8495 8496-8601 (106) AA664179 heparan sulfate

(glucosamine) 3-0- sulfotransferase 1 8602 8603-8652 (50) H86812 tubulin, alpha 2 8653 8654-8765 (112) AA626698 adenylyl cyclase- associated protein 8766 8767-8833 (67) R37953 forkhead box D1 8834 8835-8897 (63) AA069372 cathepsin C 7 (8) 1324-1627 (304) NM_001814, AA644088

ESTs, Highly similar to

AF151802 CGI-44 protein [H.sapiens] 8898 8899-8985 (87) T74688 ribonucleotide reductase

M2 polypeptide 8986 8987-9056 (70) AA187351 laminin, gamma 2 (nicein

(100kD), kalinin (105kD),

BM600 (100kD), Herlitz junctional epidermolysis bullosa)) 9057 9058-9133 (76) AA677534

Homo sapiens mRNA; cDNA DKFZp586P1622

(from clone

DKFZp586P1622) 9134 9135-9221 (87) T59658

ESTs, Weakly similar to

/prediction 9222 9223-9289 (67) AA284245 lactate dehydrogenase A 9290 9291-9369 (79) H05914 Total

98 genes 9369 (9277)

(GENBANK ACCESSION NO. M₅₅153)

AACAGGCGTGACGCCAGTTCTAAACTTGAAACAAAACAAAACTTCAAAGTACACCAAAATAGAACCTCCTTAAAGCATAAATCTCA CGGAGGGTCTCGGCCGCCAGTGGAAGGAGCCACCGCCCCCGCCCCGACCATGGCCGAGGAGCTGGTCTTAGAGAGGTGTGATCTGG AGCTGGAGACCAATGGCCGAGACCACCACACGGCCGACCTGTGCCGGGAGAAGCTGGTGGTGCGACGGGGCCAGCCCTTCTGGCT GACCCTGCACTTTGAGGGCCGCAACTACCAGGCCAGTGTAGACAGTCTCACCTTCAGTGTCGTGACCGGCCCAGCCCCTAGCCAGG AGGCCGGGACCAAGGCCCGTTTTCCACTAAGAGATGCTGTGGAGGAGGGTGACTGGACAGCCACCGTGGTGGACCAGCAAGACTG CACCCTCTCGCTGCAGCTCACCACCCCGGCCAACGCCCCCATCGGCCTGTATCGCCTCAGCCTGGAGGCCTCCACTGGCTACCAGGG ATCCAGCTTTGTGCTGGGCCACTTCATTTTGCTCTTCAACGCCTGGTGCCCAGCGGATGCTGTGTACCTGGACTCGGAAGAGGAGCG GCAGGAGTATGTCCTCACCCAGCAGGGCTTTATCTACCAGGGCTCGGCCAAGTTCATCAAGAACATACCTTGGAATTTTGGGCAGTT TCAAGATGGGATCCTAGACATCTGCCTGATCCTTCTAGATGTCAACCCCAAGTTCCTGAAGAACGCCGGCCGTGACTGCTCCCGGCG CAGCAGCCCCGTCTACGTGGGCCGGGTGGGTAGTGGCATGGTCAACTGCAACGATGACCAGGGTGTGCTGCTGGGACGCTGGGACA ACAACTACGGGGACGGCGTCAGCCCCATGTCCTGGATCGGCAGCGTGGACATCCTGCGGCGCTGGAAGAACCACGGCTGCCAGCGC GTCAAGTATGGCCAGTGCTGGGTCTTCGCCGCCGTGGCCTGCACAGTGCTGAGGTGCCTAGGCATCCCTACCCGCGTCGTGACCAAC TACAACTCGGCCCATGACCAGAACAGCAACCTTCTCATCGAGTACTTCCGCAATGAGTTTGGGGAGATCCAGGGTGACAAGAGCGA GATGATCTGGAACTTCCACTGCTGGGTGGAGTCGTGGATGACCAGGCCGGACCTGCAGCCGGGGTACGAGGGCTGGCAGGCCCTGG ACCCAACGCCCCAGGAGAAGAGCGAAGGAACGTACTGCTGTGGCCCAGTTCCAGTTCGTGCCATCAAGGAGGGCGACCTGAGCAC CAAGTACGATGCGCCCTTTGTCTTTGCGGAGGTCAATGCCGACGTGGTAGACTGGATCCAGCAGGACGATGGGTCTGTGCACAAAT CCATCAACCGTTCCCTGATCGTTGGGCTGAAGATCAGCACTAAGAGCGTGGGCCGAGACGAGCGGGAGGATATCACCCACACCTAC AAATACCCAGAGGGGTCCTCAGAGGAGAGGGAGGCCTTCACAAGGGCGAACCACCTGAACAAACTGGCCGAGAAGGAGGAGACA GGGATGGCCATGCGGATCCGTGTGGGCCAGAGCATGAACATGGGCAGTGACTTTGACGTCTTTGCCCACATCACCAACAACACCGC TGAGGAGTACGTCTGCCGCCTCCTGCTCTGTGCCCGCACCGTCAGCTACAATGGGATCTTGGGGCCCGAGTGTGGCACCAAGTACCT GCTCAACCTAACCCTGGAGCCTTTCTCTGAGAAGAGCGTTCCTCTTTGCATCCTCTATGAGAAATACCGTGACTGCCTTACGGAGTC CAACCTCATCAAGGTGCGGGCCCTCCTCGTGGAGCCAGTTATCAACAGCTACCTGCTGGCTGAGAGGGACCTCTACCTGGAGAATC CAGAAATCAAGATCCGGATCCTTGGGGAGCCCAAGCAGAAACGCAAGCTGGTGGCTGAGGTGTCCCTGCAGAACCCGCTCCCTGTG GCCCTGGAAGGCTGCACCTTCACTGTGGAGGGGGCCGGCCTGACTGAGGAGCAGAAGACGGTGGAGATCCCAGACCCCGTGGAGG

CAGGGGAGGAAGTTAAGGTGAGAATGGACCTCGTGCCGCTCCACATGGGCCTCCACAAGCTGGTGGTGAACTTCGAGAGCGACAA GCTGAAGGCTGTGAAGGGCTTCCGGAATGTCATCATTGGCCCCGCCTAAGGGACCCCTGCTCCCAGCCTGCTGAGAGCCCCCACCTT GATCCCAATCCTTATCCCAAGCTAGTGAGCAAAATATGCCCCTTATTGGGCCCCAGACCCCAGGGCAGGGTGGGCAGCCTATGGGG GCTCTCGGAAATGGAATGTGCCCCTGGCCCATCTCAGCCTCCTGAGCCTGTGGGTCCCCACTCACCCCCTTTGCTGTGAGGAATGCT CTGTGCCAGAAACAGTGGGAGCCCTGACCTGTGCTGACTGGGGCTGGGGTGAGAGAGGAAAGACCTACATTCCCTCTCCTGCCCAG

ATGCCCTTTGGAAAGCCATTGACCACCCACCATATTGTTTGATCTACTTCATAGCTCCTTGGAGCAGGCAAAAAAGGGACAGCATGC CCTTGGCTGGATCAGGAATCCAGCTCCCTAGACTGCATCCCGTACCTCTTCCCATGACTGCACCCAGCTCCAGGGGCCCTTGGGACA CCCAGAGCTGGGTGGGGACAGTGATAGGCCCAAGGTCCCCTCCACATCCCAGCAGCCCAAGCTTAATAGCCCTCCCCCTCAACCTC ACCATTGTGAAGCACCTACTATGTGCTGGGTGCCTCCCACACTTGCTGGGGCTCACGGGGCCTCCAACCCATTTAATCACCATGGGA AACTGTTGTGGGCGCTGCTTCCAGGATAAGGAGACTGAGGCTTAGAGAGAGGAGGCAGCCCCCTCCACACCAGTGGCCTCGTGGTT

ATAAGCAAGGCTGGGTAATGTGAAGGCCCAAGAGCAGAGTCTGGGCCTCTGACTCTGAGTCCACTGCTCCATTTATAACCCCAGCC TGACCTGAGAOTGTCGCAGAGGCTGTCTGGGGCCTTTATCAAAAAAAGACTCAGCCAAGACAAGGAGGTAGAGAGGGGACTGGGG GACTGGGAGTCAGAGCCCTGGCTGGGTTCAGGTCCCACGTCTGGCCAGCGACTGCCTTCTCCTCTCTGGGCCTTTGTTTCCTTGTTGG TCAGAGGAGTGATTGAACCTGCTCATCTCCAAGGATCCTCTCCACTCCATGTTTGCAATACACAATTCC (SEQ ID NO: 1)

Amino acid sequence for G-protein G-alpha H (GENBANK ACCESSION No. M55153)

MetAlaGluGluI^uVall^uGluArgCysAspLeuGluLeuGluThrAsnGlyArgAspHisHisThrAlaAspLeuCysArgGluLys euValValArgArgGlyGlnProPheT rpl^uThrl uHisPheGluGlyArgAsnTyrGlnAlaSerValAspSerLeuThrPheSerValValT rGlyProAlaProSerGlnGluAlaGlyThrLysAlaArgPheProLeuArg AspAlaValGluGluGlyAspT ThrAlaThrValValAspGlnGlnAspCysThr^ AlaSerT rGlyTyrGlnGlySerSerPheValLeuGlyHisPhelleLeu uPheAsnAlaTrpCysProAlaAspAlaValTyrLeuAspSerGluGluGluArgGlnGluTyrValLe uThrGlnGlnGlyPhelleTyrGlnGlySerAlaLysPhelleLysAsnlleProT AsnPheGlyGlnPheGlnAspGlyllel^uAspIleCysLeuIleLeul^uAspValAsnProLys PheLeuLysAsnAlaGlyArgAspCysSerArgArgSerSerProValTyrValGlyArgValGlySerGlyMetValAsnCysAsnAspAspGlnGlyValLeuLeuGlyArgTφAs pAsnAsnTyrGlyAspGlyValSerProMetSerT IleGlySerValAspIleLeuArgArgTφLysAsnHisGlyCysGlnArgValLysTyrGlyGlnCysTrpValPheΑlaAla Va laCysThrVal uArgCysI^uGlylleProThrArgVal ^ eGlnGlyAspLysSerGluMetIleTφAsnPheHisCysTφValGluSerTφMetThrArgProAspLeuGlnProGlyTyrGluGlyTφGlnAlaLeuAspProThrProGlnGlu

LysSerGluGlyThrTyrCysCysGlyProValProValArgAlalleLysGluGlyAspLeuSerThrLysTyrAspAlaProPheValPheAlaGluValAsnAlaAspValValAspTr pIleGlnGlnAspAspGlySerValHisLysSerlleAsnArgSerLeuIleValGlyl^uLysIleSerThrLysSerValGlyArgAspGluArgGluAspIleThrHisThrTyrLysTyrPr 0GluGlySerSerGluGluArgGluAlaPheThrArgAlaAsnHislΛuAsnLysl uAlaGluLysGluGluThrGlyMetAlaMetArgIleArgValGlyGlnSerMetAsnMetGl ySerAspPheAspValPheAlaHisIleT rAsnAsnThrAlaGluGluTyrValCysArgLeuLeuLeuCysAlaArgThrValSerTyrAsnGlyIleLeuGlyProGluCysGlyThr LysTyrLeuLeuAsnl uThrl^uGluProPheSerGluLysSerValProLeuCysIlel^uT^ uValGluProVallleAsnSerTyr euI uAlaGluArgAspLeuTyrLeuGluAsnProGluIleLysIleArglleLeuGlyGluPro ysGlnLysArgLysLeuValAlaGluValSer LeuGlnAsnProLeuProValAla euGluGlyCysT rPheThrValGluGlyAlaGlyLeuThrGluGluGlnLysThrValGluIleProAspProValGluAlaGlyGluGluValLy sValArgMetAspI uValProI^uHisMetGlyLeuHisLysI^uValValAsnPheGluSerAspLysLeuLysAlaValLysGlyPheArgAsnValllelleGlyProAla (SEQ ID NO: 2). (GENBANK ACCESSION NO. BC002829)

GGCACGAGGCTCCCCTCACCCCGGTCCAGGATGCCCAGTCCCCACGACACCTCCCACTTCCCACTGTGGCCTGGGTGGGCTCAGGG GCTGCCCTTGACCTGGCCTAGAGCCCTCCCCCAGCTGGTGGTGGAGCTGGCACTCTCTGGGAGGGAGGGGGCTGGGAGGGAATGAG TGGGAATGGCAAGAGGCCAGGGTTTGGTGGGATCAGGTTGAGGCAGGTTTGGTTTCCTTAAAATGCCAAGTTGGGGGCCAGTGGGG CCCACATATAAATCCTCACCCTGGGAGCCTGGCTGCCTTGCTCTCCTTCCTGGGTCTGTCTCTGCCACCTGGTCTGCCACAGATCCAT GATGTGCAGTTCTCTGGAGCAGGCGCTGGCTGTGCTGGTCACTACCTTCCACAAGTACTCCTGCCAAGAGGGCGACAAGTTCAAGCT

GAGTAAGGGGGAAATGAAGGAACTTCTGCACAAGGAGCTGCCCAGCTTTGTGGGGGAGAAAGTGGATGAGGAGGGGCTGAAGAAG CTGATGGGCAGCCTGGATGAGAACAGTGACCAGCAGGTGGACTTCCAGGAGTATGCTGTTTTCCTGGCACTCATCACTGTCATGTGC AATGACTTCTTCCAGGGCTGCCCAGACCGACCCTGAAGCAGAACTCTTGACTTCCTGCCATGGATCTTTTGGGCCCAGGACTGTTGA TGCCTTTGAGTTTTGTATTCAATAAACTTTTTTTGTCTGTTGAAAAAAAAAAAAAAAAAAAAAAAA (SEQ ID NO: 3)

Amino acid sequence for S 100A2 (GENBANK ACCESSION No. BC002₈29)

MetMetCysSerSerl^uGluGlriAlaLeuAlaVal uValThrThrPheHisLysTyrSerCysGlnGluGlyAspLysPheLysLeuSerLysGlyGluMetLysGlu eu euHis LysGlu uProSerPheValGlyGluLysValAspGluGluGlyLeuLysLysLeuMetGlySerLeuAspGluAsnSerAspGlnGlnValAspPheGlnGluTyrAlaValPheLe uAlaLeuIleThrValMetCysAsnAspPhePheGlnGlyCysProAspArgPro (SEQ ID NO: 4). (GENBANK ACCESSION NO. NM_0031₅₅)

CAGTTTGCAAAAGCCAGAGGTGCAAGAAGCAGCGACTGCAGCAGCAGCAGCAGCAGCGGCGGTGGCAGCAGCAGCAGCAGCGGC GGCAGCAGCAGCAGCAGCGGAGGCACCGGTGGCAGCAGCAGCATCACCAGCAACAACAACAAAAAAAAATCCTCATCAAATCCTC ACCTAAGCTTTCAGTGTATCCAGATCCACATCTTCACTCAAGCCAGGAGAGGGAAAGAGGAAAGGGGGGCAGGAAAAAAAAAAAA CCCAACAACTTAGCGGAAACTTCTCAGAGAATGCTCCAAAACTCAGCAGTGCTTCTGGTGCTGGTGATCAGTGCTTCTGCAACCCAT GAGGCGGAGCAGAATGACTCTGTGAGCCCCAGGAAATCCCGAGTGGCGGCTCAAAACTCAGCTGAAGTGGTTCGTTGCCTCAACAG

TGCTCTACAGGTCGGCTGCGGGGCTTTTGCATGCCTGGAAAACTCCACCTGTGACACAGATGGGATGTATGACATCTGTAAATCCTT CTTGTACAGCGCTGCTAAATTTGACACTCAGGGAAAAGCATTCGTCAAAGAGAGCTTAAAATGCATCGCCAACGGGGTCACCTCCA AGGTCTTCCTCGCCATTCGGAGGTGCTCCACTTTCCAAAGGATGATTGCTGAGGTGCAGGAAGAGTGCTACAGCAAGCTGAATGTGT GCAGCATCGCCAAGCGGAACCCTGAAGCCATCACTGAGGTCGTCCAGCTGCCCAATCACTTCTCCAACAGATACTATAACAGACTT GTCCGAAGCCTGCTGGAATGTGATGAAGACACAGTCAGCACAATCAGAGACAGCCTGATGGAGAAAATTGGGCCTAACATGGCCA

GCCTCTTCCACATCCTGCAGACAGACCACTGTGCCCAAACACACCCACGAGCTGACTTCAACAGGAGACGCACCAATGAGCCGCAG AAGCTGAAAGTCCTCCTCAGGAACCTCCGAGGTGAGGAGGACTCTCCCTCCCACATCAAACGCACATCCCATGAGAGTGCATAACC AGGGAGAGGTTATTCACAACCTCACCAAACTAGTATCATTTTAGGGGTGTTGACACACCAATTTTGAGTGTACTGTGCCTGGTTTGA TTTTTTTAAAGTAGTTCCTATTTTCTATCCCCCTTAAAGAAAATTGCATGAAACTAGGCTTCTGTAATCAATATCCCAACATTCTGCA ATGGCAGCATTCCCACCAACAAAATCCATGTGATCATTCTGCCTCTCCTCAGGAGAAAGTACCCTCTTTTACCAACTTCCTCTGCCAT

GTCTTTTCCCCTGCTCCCCTGAGACCACCCCCAAACACAAAACATTCATGTAACTCTCCAGCCATTGTAATTTGAAGATGTGGATCC CTTTAGAACGGTTGCCCCAGTAGAGTTAGCTGATAAGGAAACTTTATTTAAATGCATGTCTTAAATGCTCATAAAGATGTTAAATGG AATTCGTGTTATGAATCTGTGCTGGCCATGGACGAATATGAATGTCACATTTGAATTCTTGATCTCTAATGAGCTAGTGTCTTATGGT CTTGATCCTCCAATGTCTAATTTTCTTTCCGACACATTTACCAAATTGCTTGAGCCTGGCTGTCCAACCAGACTTTGAGCCTGCATCT TCTTGCATCTAATGAAAAACAAAAAGCTAACATCTTTACGTACTGTAACTGCTCAGAGCTTTAAAAGTATCTTTAACAATTGTCTTA AAACCAGAGAATCTTAAGGTCTAACTGTGGAATATAAATAGCTGAAAACTAATGTACTGTACATAAATTCCAGAGGACTCTGCTTA AACAAAGCAGTATATAATAACTTTATTGCATATAGATTTAGTTTTGTAACTTAGCTTTATTTTTCTTTTCCTGGGAATGGAATAACTA TCTCACTTCCAGATATCCACATAAATGCTCCTTGTGGCCTTTTTTATAACTAAGGGGGTAGAAGTAGTTTTAATTCAACATCAAAACT TAAGATGGGCCTGTATGAGACAGGAAAAACCAACAGGTTTATCTGAAGGACCCCAGGTAAGATGTTAATCTCCCAGCCCACCTCAA CCCAGAGGCTACTCTTGACTTAGACCTATACTGAAAGATCTCTGTCACATCCAACTGGAAATTCCAGGAACCAAAAAGAGCATCCCT

ATGGGCTTGGACCACTTACAGTGTGATAAGGCCTACTATACATTAGGAAGTGGTAGTTCTTTACTCGTCCCCTTTCATCGGTGCCTGG TACTCTGGCAAATGATGATGGGGTGGGAGACTTTCCATTAAATCAATCAGGAATGAGTCAATCAGCCTTTAGGTCTTTAGTCCGGGG GACTTGGGGCTGAGAGAGTATAAATAACCCTGGGCTGTCCAGCCTTAATAGACTTCTCTTACATTTTCGTCCTGTAGCACGCTGCCT GCCAAAGTAGTCCTGGCAGCTGGACCATCTCTGTAGGATCGTAAAAAAATAGAAAAAAAGAAAAAAAAAAGAAAGAAAGAGGGA AAAAGAGCTGGTGGTTTGATCATTTCTGCCATGATGTTTACAAGATGGCGACCACCAAAGTCAAACGACTAACCTATCTATGAACAA

CAGTAGTTTCTCAGGGTCACTGTCCTTGAACCCAACAGTCCCTTATGAGCGTCACTGCCCACCAAAGGTCAATGTCAAGAGAGGAA GAGAGGGAGGAGGGGTAGGACTGCAGGGGCCACTCCAAACTCGCTTAGGTAGAAACTATTGGTGCTCGACTCTCACTAGGCTAAAC TCAAGATTTGACCAAATCGAGTGATAGGGATCCTGGTGGGAGGAGAGAGGGCACATCTCCAGAAAAATGAAAAGCAATACAACTTT ACCATAAAGCCTTTAAAACCAGTAACGTGCTGCTCAAGGACCAAGAGCAATTGCAGCAGACCCAGCAGCAGCAGCAGCAGCACAA ACATTGCTGCCTTTGTCCCCACACAGCCTCTAAGCGTGCTGACATCAGATTGTTAAGGGCATTTTTATACTCAGAACTGTCCCATCCC

CAGGTCCCCAAACTTATGGACACTGCCTTAGCCTCTTGGAAATCAGGTAGACCATATTCTAAGTTAGACTCTTCCCCTCCCTCCCAC ACTTCCCACCCCCAGGCAAGGCTGACTTCTCTGAATCAGAAAAGCTATTAAAGTTTGTGTGTTGTGTCCATTTTGCAAACCCAACTA AGCCAGGACCCCAATGCGACAAGTAGTTCATGAGTATTCCTAGCAAATTTCTCTCTTTCTTCAGTTCAGTAGATTTCCTTTTTTCTTTT ACAATACATATATCTACACATACAGAAAGAAGCAGTTCTCACATGTTGCTAGTTTTTTGCTTCTCTTTCCCCCACCCTACTCCCTCCA

ATTCCCCCCTTAAACTTCCAAAGCTTCGTCTTGTGTTTGCTGCAGAGTGATTCGGGGGCTGACCTAGACCAGTTTGCATGATTCTTCT CTTGTGATTTGGTTGCACTTTAGACATTTTTGTGCCATTATATTTGCATTATGTATTTATAATTTAAATGATATTTAGGTTTTTGGCTG AGTACTGGAATAAACAGTGAGCATATCTGGTATATGTCATTATTTATTGTTAAATTACATTTTTTAAGCTCCATGTGCATATAAAGGT TATGAAACATATCATGGTAATGACAGATGCAAGTTATTTTATTTGCTTATTTTTTATAATTAAAGATGCCATAGCATAATATGAAGCC TTTGGTGAATTCCTTCTAAGATAAAAATAATAATAAAGTGTTACGTTTTATTGGTTTCAAAAAAAAAAAAAAAAAAAA

(SEQ ID NO: 5)

Amino acid sequence for Stanniocalcin 1 (GENBANK ACCESSION No. NM_003155)

MetLeuGlnAsnSerAlaValLeuLeuValLeuVallleSerAlaSerAlaThrHisGluAlaGluGlnAsnAspSerValSerProArgLysSerA rgValAlaAlaGlnAsnSerAlaGluValValArgCysLeuAsnSerAlaLeuGlnValGlyCysGlyAlaPheAlaCysLeuGluAsnSerT rCy sAspThrAspGlyMetTyrAspIleCysLysSerPheLeuTyrSerAlaAla ysPheAspT rGlnGly ysAlaP eVal ysGluSer euLys

CysIleAlaAsnGlyValThrSerLysValP e euAlalleArgArgCysSerT rPheGlnArgMetlleAlaGluValGlnGluGluCysTyrS erLysLeuAsnValCysSerlleAlaLysArgAsnProGluAlalleThrGluValValGlnLeuProAsnHisPheSerAsnArgTyrTyrAsnAr gLeuValArgSerLeu euGluCysAspGluAspThrValSerThrlleArgAspSerLeuMetGluLysIleGlyProAsnMetAlaSerLeuPhe HisIleLeuGlnThrAspHisCysAlaGlnThrHisProArgAlaAspPheAsriArgArgArgThrAsnGluProGlnLysLeuLysValLeuIjeuA rgAsnLeuArgGlyGluGluAspSerProSerHisIleLysArgThrSerHisGluSerAla (SEQ ID NO: 6).

(GENBANK ACCESSION NO. NM_001814)

AATTCTTCACCTCTTTTCTCAGCTCCCTGCAGCATGGGTGCTGGGCCCTCCTTGCTGCTCGCCGCCCTCCTGCTGCTTCTCTCCGGCG ACGGCGCCGTGCGCTGCGACACACCTGCCAACTGCACCTATCTTGACCTGCTGGGCACCTGGGTCTTCCAGGTGGGCTCCAGCGGTT CCCAGCGCGATGTCAACTGCTCGGTTATGGGACCACAAGAAAAAAAAGTAGTGGTGTACCTTCAGAAGCTGGATACAGCATATGAT GACCTTGGCAATTCTGGCCATTTCACCATCATTTACAACCAAGGCTTTGAGATTGTGTTGAATGACTACAAGTGGTTTGCCTTTTTTA

AGTATAAAGAAGAGGGCAGCAAGGTGACCACTTACTGCAACGAGACAATGACTGGGTGGGTGCATGATGTGTTGGGCCGGAACTG GGCTTGTTTCACCGGAAAGAAGGTGGGAACTGCCTCTGAGAATGTGTATGTCAACACAGCACACCTTAAGAATTCTCAGGAAAAGT ATTCTAATAGGCTCTACAAGTATGATCACAACTTTGTGAAAGCTATCAATGCCATTCAGAAGTCTTGGACTGCAACTACATACATGG AATATGAGACTCTTACCCTGGGAGATATGATTAGGAGAAGTGGTGGCCACAGTCGAAAAATCCCAAGGCCCAAACCTGCACCACTG ACTGCTGAAATACAGCAAAAGATTTTGCATTTGCCAACATCTTGGGACTGGAGAAATGTTCATGGTATCAATTTTGTCAGTCCTGTT

CGAAACCAAGCATCCTGTGGCAGCTGCTACTCATTTGCTTCTATGGGTATGCTAGAAGCGAGAATCCGTATACTAACCAACAATTCT CAGACCCCAATCCTAAGCCCTCAGGAGGTTGTGTCTTGTAGCCAGTATGCTCAAGGCTGTGAAGGCGGCTTCCCATACCTTATTGCA GGAAAGTACGCCCAAGATTTTGGGCTGGTGGAAGAAGCTTGCTTCCCCTACACAGGCACTGATTCTCCATGCAAAATGAAGGAAGA CTGCTTTCGTTATTACTCCTCTGAGTACCACTATGTAGGAGGTTTCTATGGAGGCTGCAATGAAGCCCTGATGAAGCTTGAGTTGGTC CATCATGGGCCCATGGCAGTTGCTTTTGAAGTATATGATGACTTCCTCCACTACAAAAAGGGGATCTACCACCACACTGGTCTAAGA

GACCCTTTCAACCCCTTTGAGCTGACTAATCATGCTGTTCTGCTTGTGGGCTATGGCACTGACTCAGCCTCTGGGATGGATTACTGGA TTGTTAAAAACAGCTGGGGCACCGGCTGGGGTGAGAATGGCTACTTCCGGATCCGCAGAGGAACTGATGAGTGTGCAATTGAGAGC ATAGCAGTGGCAGCCACACCAATTCCTAAATTGTAGGGTATGCCTTCCAGTATTTCATAATGATCTGCATCAGTTGTAAAGGGGAAT TGGTATATTCACAGACTGTAGACTTTCAGCAGCAATCTCAGAAGCTTACAAATAGATTTCCATGAAGATATTTGTCTTCAGAATTAA AACTGCCCTTAATTTTAATATACCTTTCAATCGGCCACTGGCCATTTTTTTCTAAGTATTCAATTAAGTGGGAATTTTCTGGAAGATG

GTCAGCTATGAAGTAATAGAGTTTGCTTAATCATTTGTAATTCAAACATGCTATATTTTTTAAAATCAATGTGAAAACATAGACTTAT TTTTAAATTGTACCAATCACAAGAAAATAATGGCAATAATTATCAAAACTTTTAAAATAGATGCTCATATTTTTAAAATAAAGTTTT AAAAATAACTGC (SEQ ID NO: 7) Amino acid sequence for Cathepsin C (GENBANK ACCESSION No. NM_001814)

Me GlyAlaGlyProSerTjeu euLeuAlaAla euLeuLeuLeu euSerGlyAspGlyAlaValArgCysAspThrProAlaAsnCysTrirTyrl, e AspLeuLeuGlyThrTrpValPheGlnValGlySerSerGlySerGlnArgAspValAsnCysSerValMetGlyProGlnGluIiys ysValVa lValTyrLeuGln-iysLeuAspThrAlaTyrAspAspLeuGlyAsnSerGlyHisPheThrllelleTyrAsnGlnGlyP eGluIleVallieuAsn AspTyr ysTrpPheAlaPhePheliysTyr ysGluGluGlySer ysValThrThrTyrCysAsnGluThrMetT rGlyTrpValHisAspValL euGlyArgAsnTrpAlaCysPheThrGlyLysLysValGlyThrAlaSerGluAsnValTyrValAsnThrAlaHisLeuLysAsnSerGlnGlu y sTyrSerAsnArgLeuTyrLysTyrAspHisAsnPheVal ysAlalleAsnAlalleGliiIiysSerTrpThrAlaThrThrTyrMetGluTyrGlu ThrLeuThrLeuGlyAspMetlleArgArgSerGlyGlyHisSerArgLysIleProArgProLyBProAlaProLeuThrAlaGluIleGlnGlnL ysIleLeuHis euProThrSerTrpAspTrpArgAsnValHisGlylleAsnPheValSerProValArgAsnGlnAlaSerCysGlySerCysTy rSerPheAlaSerMetGlyMetLeuGluAlaArglleArglle euThrAsnAsnSerGlnThrProIleLeuSerProGlnGl ValValSerCys SerGlnTyrAlaGlnGlyCysGluGlyGlyPheProTyrLeuIleAlaGly ysTyrAlaGlnAspPheGlyLeuValGluGluAlaCysPheProT yrThrGlyThrAspSerProCysLysMetLysGl AspCysPheArgTyrTyrSerSerGluTyrHisTyrValGlyGlyPheTyrGlyGlyCysAs nGluAla euMet ysLeuGluLeuValHisHisGlyProMetAlaValAlaPheGluValTyrAspAspPheLeuHisTyrLys ysGlyllβTyr HisHisThrGlyLeuArgAspProPheAsnProPheGluLeuThrAsnHisAlaValLe LeuValGlyTyrGlyThrAspSerAlaSerGlyMetA spTyrTrpIleValLysAsnSerTrpGlyThrGlyTrpGlyGluAsnGlyTyrPheArglleArgArgGlyThrAspGluCysAlalleGluSβrll eAlaValAlaAlaThrProIlePro ysLeu (SEQ ID NO: 8). (GENBANK ACCESSION NO. NM_012334)

GAGACAAAGGCTGCCGTCGGGACGGGCGAGTTAGGGACTTGGGTTTGGGCGAACAAAAGGTGAGAAGGACAAGAAGGGACCGGG CGATGGCAGCAGGGGAGCCCCGCGGGCGCGCGTCCTCGGGAGTGGCGCCGTGACACGCATGGTTTCCCCGGACCCGCGGCGGCGCT GACTTCCGCGAGTCGGAGCGGCACTCGGCGAGTCCGGGACTGCGCTGGAACAATGGATAACTTCTTCACCGAGGGAACACGGGTCT GGCTGAGAGAAAATGGCCAGCATTTTCCAAGTACTGTAAATTCCTGTGCAGAAGGCATCGTCGTCTTCCGGACAGACTATGGTCAG

GTATTCACTTACAAGCAGAGCACAATTACCCACCAGAAGGTGACTGCTATGCACCCCACGAACGAGGAGGGCGTGGATGACATGGC GTCCTTGACAGAGCTCCATGGCGGCTCCATCATGTATAACTTATTCCAGCGGTATAAGAGAAATCAAATATATACCTACATCGGCTC CATCCTGGCCTCCGTGAACCCCTACCAGCCCATCGCCGGGCTGTACGAGCCTGCCACCATGGAGCAGTACAGCCGGCGCCACCTGG GCGAGCTGCCCCCGCACATCTTCGCCATCGCCAACGAGTGCTACCGCTGCCTGTGGAAGCGCTACGACAACCAGTGCATCCTCATCA GTGGTGAAAGTGGGGCAGGTAAAACCGAAAGCACTAAATTGATCCTCAAGTTTCTGTCAGTCATCAGTCAACAGTCTTTGGAATTGT

CCTTAAAGGAGAAGACATCCTGTGTTGAACGAGCTATTCTTGAAAGCAGCCCCATCATGGAAGCTTTCGGCAATGCGAAGACCGTG TACAACAACAACTCTAGTCGCTTTGGGAAGTTTGTTCAGCTGAACATCTGTCAGAAAGGAAATATTCAGGGCGGGAGAATTGTAGA TTATTTATTAGAAAAAAACCGAGTAGTAAGGCAAAATCCCGGGGAAAGGAATTATCACATATTTTATGCACTGCTGGCAGGGCTGG AACATGAAGAAAGAGAAGAATTTTATTTATCTACGCCAGAAAACTACCACTACTTGAATCAGTCTGGATGTGTAGAAGACAAGACA ATCAGTGACCAGGAATCCTTTAGGGAAGTTATTACGGCAATGGACGTGATGCAGTTCAGCAAGGAGGAAGTTCGGGAAGTGTCGAG

GCTGCTTGCTGGTATACTGCATCTTGGGAACATAGAATTTATCACTGCTGGTGGGGCACAGGTTTCCTTCAAAACAGCTTTGGGCAG ATCTGCGGAGTTACTTGGGCTGGACCCAACACAGCTCACAGATGCTTTGACCCAGAGATCAATGTTCCTCAGGGGAGAAGAGATCC TCACGCCTCTCAATGTTCAACAGGCAGTAGACAGCAGGGACTCCCTGGCCATGGCTCTGTATGCGTGCTGCTTTGAGTGGGTAATCA AGAAGATCAACAGCAGGATCAAAGGCAATGAGGACTTCAAGTCTATTGGCATCCTCGACATCTTTGGATTTGAAAACTTTGAGGTT AATCACTTTGAACAGTTCAATATAAACTATGCAAACGAGAAACTTCAGGAGTACTTCAACAAGCATATTTTTTCTTTAGAACAACTA

GAATATAGCCGGGAAGGATTAGTGTGGGAAGATATTGACTGGATAGACAATGGAGAATGCCTGGACTTGATTGAGAAGAAACTTGG CCTCCTAGCCCTTATCAATGAAGAAAGCCATTTTCCTCAAGCCACAGACAGCACCTTATTGGAGAAGCTACACAGTCAGCATGCGA ATAACCACTTTTATGTGAAGCCCAGAGTTGCAGTTAACAATTTTGGAGTGAAGCACTATGCTGGAGAGGTGCAATATGATGTCCGAG GTATCTTGGAGAAGAACAGAGATACATTTCGAGATGACCTTCTCAATTTGCTAAGAGAAAGCCGATTTGACTTTATCTACGATCTTT TTGAACATGTTTCAAGCCGCAACAACCAGGATACCTTGAAATGTGGAAGCAAACATCGGCGGCCTACAGTCAGCTCACAGTTCAAG

GACTCACTGCATTCCTTAATGGCAACGCTAAGCTCCTCTAATCCTTTCTTTGTTCGCTGTATCAAGCCAAACATGCAGAAGATGCCA GACCAGTTTGACCAGGCGGTTGTGCTGAACCAGCTGCGGTACTCAGGGATGCTGGAGACTGTGAGAATCCGCAAAGCTGGGTATGC GGTCCGAAGACCCTTTCAGGACTTTTACAAAAGGTATAAAGTGCTGATGAGGAATCTGGCTCTGCCTGAGGACGTCCGAGGGAAGT GCACGAGCCTGCTGCAGCTCTATGATGCCTCCAACAGCGAGTGGCAGCTGGGGAAGACCAAGGTCTTTCTTCGAGAATCCTTGGAA CAGAAACTGGAGAAGCGGAGGGAAGAGGAAGTGAGCCACGCGGCCATGGTGATTCGGGCCCATGTCTTGGGCTTCTTAGCACGAA

AACAATACAGAAAGGTCCTTTATTGTGTGGTGATAATACAGAAGAATTACAGAGCATTCCTTCTGAGGAGGAGATTTTTGCACCTGA AAAAGGCAGCCATAGTTTTCCAGAAGCAACTCAGAGGTCAGATTGCTCGGAGAGTTTACAGACAATTGCTGGCAGAGAAAAGGGA GCAAGAAGAAAAGAAGAAACAGGAAGAGGAAGAAAAGAAGAAACGGGAGGAAGAAGAAAGAGAAAGAGAGAGAGAGCGAAGA GAAGCCGAGCTCCGCGCCCAGCAGGAAGAAGAAACGAGGAAGCAGCAAGAACTCGAAGCCTTGCAGAAGAGCCAGAAGGAAGCT GAACTGACCCGTGAACTGGAGAAACAGAAGGAAAATAAGCAGGTGGAAGAGATCCTCCGTCTGGAGAAAGAAATCGAGGACCTGC

AGCGCATGAAGGAGCAGCAGGAGCTGTCGCTGACCGAGGCTTCCCTGCAGAAGCTGCAGGAGCGGCGGGACCAGGAGCTCCGCAG GCTGGAGGAGGAAGCGTGCAGGGCGGCCCAGGAGTTCCTCGAGTCCCTCAATTTCGACGAGATCGACGAGTGTGTCCGGAATATCG AGCGGTCCCTGTCGGTGGGAAGCGAATTTTCCAGCGAGCTGGCTGAGAGCGCATGCGAGGAGAAGCCCAACTTCAACTTCAGCCAG CCCTACCCAGAGGAGGAGGTCGATGAGGGCTTCGAAGCCGACGACGACGCCTTCAAGGACTCCCCCAACCCCAGCGAGCACGGCC ACTCAGACCAGCGAACAAGTGGCATCCGGACCAGCGATGACTCTTCAGAGGAGGACCCATACATGAACGACACGGTGGTGCCCAC

CAGCCCCAGTGCGGACAGCACGGTGCTGCTCGCCCCATCAGTGCAGGACTCCGGGAGCCTACACAACTCCTCCAGCGGCGAGTCCA CCTACTGCATGCCCCAGAACGCTGGGGACTTGCCCTCCCCAGACGGCGACTACGACTACGACCAGGATGACTATGAGGACGGTGCC ATCACTTCCGGCAGCAGCGTGACCTTCTCCAACTCCTACGGCAGCCAGTGGTCCCCCGACTACCGCTGCTCTGTGGGGACCTACAAC AGCTCGGGTGCCTACCGGTTCAGCTCTGAGGGGGCGCAGTCCTCGTTTGAAGATAGTGAAGAGGACTTTGATTCCAGGTTTGATACA GATGATGAGCTTTCATACCGGCGTGACTCTGTGTACAGCTGTGTCACTCTGCCGTATTTCCACAGCTTTCTGTACATGAAAGGTGGCC

TGATGAACTCTTGGAAACGCCGCTGGTGCGTCCTCAAGGATGAAACCTTCTTGTGGTTCCGCTCCAAGCAGGAGGCCCTCAAGCAA GGCTGGCTCCACAAAAAAGGGGGGGGCTCCTCCACGCTGTCCAGGAGAAATTGGAAGAAGCGCTGGTTTGTCCTCCGCCAGTCCAA GCTGATGTACTTTGAAAACGACAGCGAGGAGAAGCTCAAGGGCACCGTAGAAGTGCGAACGGCAAAAGAGATCATAGATAACACC ACCAAGGAGAATGGGATCGACATCATTATGGCCGATAGGACTTTCCACCTGATTGCAGAGTCCCCAGAAGATGCCAGCCAGTGGTT CAGCGTGCTGAGTCAGGTCCACGCGTCCACGGACCAGGAGATCCAGGAGATGCATGATGAGCAGGCAAACCCACAGAATGCTGTG

GGCACCTTGGATGTGGGGCTGATTGATTCTGTGTGTGCCTCTGACAGCCCTGATAGACCCAACTCGTTTGTGATCATCACGGCCAAC CGGGTGCTGCACTGCAACGCCGACACGCCGGAGGAGATGCACCACTGGATAACCCTGCTGCAGAGGTCCAAAGGGGACACCAGAG TGGAGGGCCAGGAATTCATCGTGAGAGGATGGTTGCACAAAGAGGTGAAGAACAGTCCGAAGATGTCTTCACTGAAACTGAAGAA ACGGTGGTTTGTACTCACCCACAATTCCCTGGATTACTACAAGAGTTCAGAGAAGAACGCGCTCAAACTGGGGACCCTGGTCCTCA ACAGCCTCTGCTCTGTCGTCCCCCCAGATGAGAAGATATTCAAAGAGACAGGCTACTGGAACGTCACCGTGTACGGGCGCAAGCAC

TGTTACCGGCTCTACACCAAGCTGCTCAACGAGGCCACCCGGTGGTCCAGTGCCATTCAAAACGTGACTGACACCAAGGCCCCGAT CGACACCCCCACCCAGCAGCTGATTCAAGATATCAAGGAGAACTGCCTGAACTCGGATGTGGTGGAACAGATTTACAAGCGGAACC CGATCCTTCGATACACCCATCACCCCTTGCACTCCCCGCTCCTGCCCCTTCCGTATGGGGACATAAATCTCAACTTGCTCAAAGACA AAGGCTATACCACCCTTCAGGATGAGGCCATCAAGATATTCAATTCCCTGCAGCAACTGGAGTCCATGTCTGACCCAATTCCAATAA TCCAGGGCATCCTACAGACAGGGCATGACCTGCGACCTCTGCGGGACGAGCTGTACTGCCAGCTTATCAAACAGACCAACAAAGTG

CCCCACCCCGGCAGTGTGGGCAACCTGTACAGCTGGCAGATCCTGACATGCCTGAGCTGCACCTTCCTGCCGAGTCGAGGGATTCTC AAGTATCTCAAGTTCCATCTGAAAAGGATACGGGAACAGTTTCCAGGAACCGAGATGGAAAAATACGCTCTCTTCACTTACGAATC TCTTAAGAAAACCAAATGCCGAGAGTTTGTGCCTTCCCGAGATGAAATAGAAGCTCTGATCCACAGGCAGGAAATGACATCCACGG TCTATTGCCATGGCGGCGGCTCCTGCAAGATCACCATCAACTCCCACACCACTGCTGGGGAGGTGGTGGAGAAGCTGATCCGAGGC CTGGCCATGGAGGACAGCAGGAACATGTTTGCTTTGTTTGAATACAACGGCCACGTCGACAAAGCCATTGAAAGTCGAACCGTCGT

AGCTGATGTCTTAGCCAAGTTTGAAAAGCTGGCTGCCACATCCGAGGTTGGGGACCTGCCATGGAAATTCTACTTCAAACTTTACTG CTTCCTGGACACAGACAACGTGCCAAAAGACAGTGTGGAGTTTGCATTTATGTTTGAACAGGCCCACGAAGCGGTTATCCATGGCC ACCATCCAGCCCCGGAAGAAAACCTCCAGGTTCTTGCTGCCCTGCGACTCCAGTATCTGCAGGGGGATTATACTCTGCACGCTGCCA TCCCACCTCTCGAAGAGGTTTATTCCCTGCAGAGACTCAAGGCCCGCATCAGCCAGTCAACCAAAACCTTCACCCCTTGTGAACGGC TGGAGAAGAGGCGGACGAGCTTCCTAGAGGGGACCCTGAGGCGGAGCTTCCGGACAGGATCCGTGGTCCGGCAGAAGGTCGAGGA

GGAGCAGATGCTGGACATGTGGATTAAGGAAGAAGTCTCCTCTGCTCGAGCCAGTATCATTGACAAGTGGAGGAAATTTCAGGGAA TGAACCAGGAACAGGCCATGGCCAAGTACATGGCCTTGATCAAGGAGTGGCCTGGCTATGGCTCGACGCTGTTTGATGTGGAGTGC AAGGAAGGTGGCTTCCCTCAGGAACTCTGGTTGGGTGTCAGCGCGGACGCCGTCTCCGTCTACAAGCGTGGAGAGGGAAGACCACT GGAAGTCTTCCAGTATGAACACATCCTCTCTTTTGGGGCACCCCTGGCGAATACGTATAAGATCGTGGTCGATGAGAGGGAGCTGCT CTTTGAAACCAGTGAGGTGGTGGATGTGGCCAAGCTCATGAAAGCCTACATCAGCATGATCGTGAAGAAGCGCTACAGCACGACAC GCTCCGCCAGCAGCCAGGGCAGCTCCAGGTGAAGGCGGGACAGAGCCCACCTGTCTTTGCTACCTGAACGCACCACCCTCTGGCCT AGGCTGGCTCCAGTGTGCCATGCCCAGCCAAAACAAACACAGAGCTGCCCAGGCTTTCTGGAAGCTTCTGGTCTGAGGGAGGTGTC TCCGAGGATCCTTTTGCCTGCCGCCTTCATTGATCCTGTATTAAGCTGTCAACTTTAACAGTCTGCACAGTTTCCAAAGCTTTACTAC TCTTAGAGGACACATGCCTTAAAAAAGGAGGGGAGGAACCACGCTGCCACCAAAGCAGCCGGAAGTGCCTTAACTTGTGGAACCA ACACTAATCGACCGTAACTGTGCTACTGAAGGGAACTGCCTTTCCCCCTTCTGGGGGAGACTTAACAGAGCGTGGAAGGGGGGCAT TCTCTGTCAATGATGCACTAACCTCCCAACCTGATTTCCCCGAATCTGAGGGAAGGTGAGGGAGTGGGAAGGGGGATGGAGAGCTC GAGGGGACAGTGTGTTTGAGCTGGAGTGCTGCGGGCAGCCTTTCTCATGGAATGACATGAATCAACTTTTTTCTTTGTTTCATCTTTT AAGTGTACGTGCTTGCCTGTTCGTGCATGTGTTCATAAACTCAACACTTTAATCATGGTTTCATGAGCATTAAAAAGCAAAGGGAAA AAGGATGTGTAATGGTGTACACAGTCTGTATATTTTAATAATGCAGAGCTATAGTCTCAATTGTTACTTTATAAGGTGGTTTTATTAA CAAACCCAAATCCTGGATTTTCCTGTCTTTGCTGTATTTTGAAAAACACGTGTTGACTCCATTGTTTTACATGTAGCAAAGTCTGCCA TCTGTGTCTGCTGTATTATAAACAGATAAGCAGCCTACAAGATAACTGTATTTATAAACCACTCTTCAACAGCTGGCTCCAGTGCTG GTTTTAGAACAAGAATGAAGTCATTTTGGAGTCTTTCATGTCTAAAAGATTTAAGTTAAAAACAAAGTGTTACTTGGAAGGTTAGCT TCTATCATTCTGGATAGATTACAGATATAATAACCATGTTGACTATGGGGGAGAGACGCTGCATTCCAGAAACGTCTTAACACTTGA GTGAATCTTCAAAGGACCCTGACATTAAATGCTGAGGCTTTAATACACACATATTTTATCCCAAGTTTATAATGGTGGTCTGAACAA GGCACCTGTAAATAAATCAGCATTTATGACCAGAAGAAAAATAATCTGGTCTTGGACTTTTTATTTTTATATGGAAAAGTTTTAAGG ACTTGGGCCAACTAAGTCTACCCACACGAAAAAAGAAATTTGCCTTGTCCCTTTGTGTACAACCATGCAAAACTGTTTGTTGGCTCA CAGAAGTTCTGACAATAAAAGATACTAGCT (SEQ ID NO: 9) Amino acid sequence for Mvosin X (GENBANKACCESSIONNo. NM-012334) MetAspAsnPhePheThrGluGlyThrArgValTrpLeuArgGluAsnGlyGlnHisPheProSerThrValAsnSerCysAlaGluGlylleValV alPlieArgThrAspTyrGlyGlnValPheThrTyrLysGlnSerThrlleThrHisGln ysValThrAlaMetHisProThrAsnGluGluGlyVa lAspAspMetAlaSer euThrGluLeuHisGlyGlySerlleMetTyrAsriLeuPheGlnArgTyrysArgAsnGlnlleTyrThrTyrlleGly SerllelieuAlaSerValAsnProTyrGlnProIleAlaGlyLe TyrGl ProAlaThrMetGluGlnTyrSerArgArgHisIieuGlyGluLeuP roProHisIlePheAlalleAlaAsnGluCysTyrArgCysLeuTrpLysArgTyrAspAsnGlnCysIleLeuIleSerGlyGluSerGlyAlaGl yLysT rGluSerThrLys euIle euLysPhe euSerVallleSerGlnGlnSerLe GluLeuSerLeuLysGluLysThrSerCysValGlu ArgAlalleLeuGluSerSerProIleMetGluAlaPheGlyAsnAla ysThrValTyrAsnAsriAsnSerSerArgPheGlyLysPheValGlnL euAsnlleCysGlnLysGlyAsnlleGlnGlyGlyArglleValAspTyr eu euGluLysAsnArgValValArgGlnAsnProGlyGluArgAs nTyrHisIlePheTyrAlaLeuLeuAlaGlyLeuGluHisGluGluArgGluGluPheTyr euSerThrProGluAsnTyrHisTyrLeuAsnGln SerGlyCysValGluAspLysThrlleSerAspGlnGluSerPlieArgGluVallleThrAlaMetAspValMetGlnPheSerLysGluGluValA rgGluValSerArgLeuLeuAlaGlylleLeuHisIieuGlyAsnlleGluPhelleThrAlaGlyGlyAlaGlnValSerPhe ysThrAlaLeuGl yArgSerAlaGluLeu euGlyTeuAspProThrGlnLeuThrAspAlaLeuThrGlnArgSerMetPheLeuArgGlyGluGluIlelieuThrPro LeuAsnValGlnGlnAlaValAspSerArgAspSerLeuAlaMetAlaLeuTyrAlaCysCysPheGl TrpVallle ysLysIleAsnSerArgl le ysGlyAsnGluAspPhe ysSerlleGlylle euAspIlePheGlyPheGluAsnPheGluValAsnHisPheGluGlnPheAsnlleAsnTy rAlaAsnGluLys e GlnGluTyrPheAsnLysHisIlePheSerLeuGluGlriljeuGluTyrSerArgGluGlyLeuValTrpGluAspIleAsp TrpIleAspAsnGlyGluCysLeuAspLeuIleGlu ys ys euGly eu euAlaLeuIleAsnGluGluSerHisPheProGlnAlaTlirAapS erThr e e Gl LysLeuHisSerGlnHisAlaAsnAsnHisPheTyrValLysProArgValAlaValAsnAsnPheGlyValLysHisTyrAl aGlyGluValGlriTyrAspValArgGlylle euGluLysAsiiArgAspThrPheArgAspAsp eu euAsnLeuLeuArgGluSerArgPheAsp PhelleTyrAsp euPheGluHisValSerSerArgAsnAsnGlnAspThrLeuLysCysGlySerLysHisArgArgProThrValSerSerGlnP heLysAspSerLeuHisSer euMetAlaThrLeuSerSerSerAsnProPhePheValArgCysIleLysProAsnMetGlnLysMetProAspGl nPheAspGlnAlaValValLeuAsnGlnTeuArgTyrSerGlyMet euGluTlirValArglleArgLysAlaGlyTyrAlaValArgArgProPhe GlnAspPheTyrysArgTyrLysVal euMetArgAsnLeuAlaLeuProGluAspValArgGlyLysCysThrSerLeuTjeuGlnlieuTyrAspA laSerAsriSerGluTrpGln euGlyliysThrLysValPheLeuArgGluSerLeuGluGlnliysLeuGluLysArgArgGluGl Gl ValSerHi sAlaAlaMetVallleArgAlaHisVal euGlyPheLeuAlaArgysGlnTyrArgLysValLeuTyrCysValValllelleGlnLysAsnTyr ArgAlaPheLeuLe ArgArgArgPheLeuHis euLysLysAlaAlalleValPheGlnLysGlnLeuArgGlyGlnlleAlaArgArgValTyrA rgGln euLeuAlaGlu ysArgGluGlnGluGluLysLysLysGlnGluGluGluGluLysLysLysArgGluGluGluGluArgGluArgGluAr gGluArgArgGluAlaGluLeuArgAlaGlnGlnGluGluGluThrArgLysGlnGlnGluLeuGluAlaLeuGlnLysSerGlnLysGluAlaGlu LeuThrArgGluLeuGluLysGlnLysGluAsriLysGlnValGluGluIle euArgLeuGluLysGluIleGluAspLeuGlnArgMetLysGluG lnGlnGluLeuSerLeuThrGluAlaSerlieuGlnLys euGlnGluArgArgAspGlnGluIjeuArgArgLeuGluGluGluAlaCysArgAlaAl aGlnGluPheLeuGluSerLeuAsnPheAspGluIleAspGl CysValArgAsnlleGluArgSerLeuSerValGlySerGluPheSerSerGlu Le AlaGluSerAlaCysGluGlu ysProAsnPheAsnPheSerGlnProTyrProGluGl-uGluValAspGluGlyPheGluAlaAspAspAspA laPheLysAspSerProAsnProSerGluHisGlyHisSerAspGlnArgThrSerGlylleArgThrSer spAspSerSerGluGluAspProTy rMetAsriAspThrValValProThrSerProSerAlaAspSerT rValLeu euAlaProSerValGlnAspSerGlySer euHisAsnSerSer SerGlyGl SerT rTyrCysMetProGlnAsriAlaGlyAspLeuProSerProAspGlyAspTyrAspTyrAspGlnAspAspTyrGluAspGlyA lalleThrSerGlySerSerValThrPheSerAsnSerTyrGlySerGlnTrpSerProAspTyrArgCysSerValGlyThrTyrAsnSerSerGl yAlaTyrArgPheSerSerGluGlyAlaGlnSerSerPheGluAspSerGluGliAspPheAspSerArgPheAspThrAspAspGluLeuSerTyr ArgArgAspSerValTyrSerCysValT r euProTyrPheHisSerPhe euTyrMet ysGlyGlyLeu etAsnSerTrpLysArgArgTrpC ysVallieu ysAspGluThrPheLeuTrpPheArgSerLysGlnGluAlaLeu ysGlnGlyTrpIeuHis ysLysGlyGlyGlySerSerThrLe SerArgArgAsnTrpLysLysArgTrpPheValLeuArgGlnSerLysLe MetTyrPheGluAsnAspSerGluGl LysLeuLysGlyThrVal GluValArgThrAlaLysGluIlelleAspAsnThrThrLysGluAsnGlylleAspIlelleMetAlaAspArgThrPheHis euIleAlaGluS erProGluAspAlaSerGlnTrpPheSerValLeuSerGlnValHisAlaSerThrAspGlnGluIleGlnGluMetHisAspGluGlnAlaAsriPr oGlnAsnAlaValGlyThr euAspValGlyLeuIleAspSerValCysAlaSerAspSerProAspArgProAsnSerPheValllelleThrAla AsnArgVal euHlsCysAsriAlaAspTlirProGluGl MetHisHisTrpIleThr eu euGlnArgSer ysGlyAspThrArgValGluGlyG InGluPhelleValArgGlyTrpLeuHisLysGluVal ysAsnSerProLysMetSerSerLeuLiys e-uLysLysArgTrpPheValLeuThrHi sAsnSerLeuAspTyrTyrLysSerSerGluLysAsnAla e'uLysLeuGlyTrirLeuVal euAsnSerLe'uCysSerValValProProAspGl-u LysIlePheLysGluThrGlyTyrTrpAsnValThrValTyrGlyArgLysHisCysTyrArgLe TyrThr ysLeuLeuAsnGluAlaThrArgT rpSerSerAlalleGlnAsnValThrAspThr ysAlaProIleAspT rProThrGlnGlnLeuIleGlnAspIleLysGluAsnCysLeuAsnSe rAspValValGluGlnlleTyrLysArgAsnProIleLe ArgTyrThrHisHisProLeuHisSerProLeuIieuProLeuProTyrGlyAspIle AsnLeuAsnLeuLeuLysAspLysGlyTyrThrThrLeuGlnAspGluAlalle ysIlePheAsnSerLeuGlnGlnLeuGluSerMetSerAspP roIleProIlelleGlnGlylleLeuGlnThrGlyHisAsp euArgProLieuArgAspGluLeuTyrCysGlnLeuIle ysGlnThrAsnLysVa lPrσHisProGlySerValGlyAsn euTyrSerTrpGlnllelieuThrCysLeuSerCysThrPhelieuProSerArgGlylle euLysTyrLeu LysPheHis euLysArglleArgGluGlnPheProGlyThrGluMetGluLysTyrAlaLeuPheThrTyrGluSerlieuLysLysThrLysCysA rgGluPheValProSerArgAspGluIleGl AlaLeuIleHisArgGlnGluMetThrSerThrValTyrCysHisGlyGlyGlySerCys ysIl eThrlleAsnSerHisThrThrAlaGlyGluValValGluLysLeuIleArgGlyLeuAlaMetGluAspSerArgAsnMetPheAla euPheGlu TyrAsnGlyHisValAsp ysAlalleGluSerArgThrValValAlaAspVal euAla ysPheGluLysIieuAlaAlaThrSerGluValGlyA spLeuProTrp ysPheTyrPheLysLeuTyrCysPheLeuAspThrAspAsnValPro ysAspSerValGluPheAlaPheMetPheGluGlnAl aHisGluAlaVallleHisGlyHisHisProAlaProGl GluAsriLeuGlriValLeuAlaAlalieuArg euGlnTyrLeuGlnGlyAspTyrThr euHisAlaAlalleProProLeuGluGluValTyrSerLeuGlnArgLeuLysAlaArglleΞerGlnSerThrLysThrPheThrProCysGluA rgLeuGlu ysArgArgThrSerPheLeuGluGlyT rLeuArgArgSerPheArgThrGlySerValValArgGlnLysValGluGluGluGlriMe tLeuAspMetTrpIleLysGluGluValSerSerAlaArgAlaSerllelleAsp ysTrpArgLysPheGlnGlyMetAsnGlnGluGlnAlaMet AlaLysTyr etAlaLeuIleLysGluTrpProGlyTyrGlySerThrLeuPheAspValGluCysLysGluGlyGlyPheProGlnGl LeuTrpL euGlyValSerAlaAspAlaValSerValTyr ysArgGlyGluGlyArgProLeuGluValPheGlnTyrGluHisIleLeuSerPheGlyAlaPr 0 euAlaAsnThrTyr ysIleValValAspGluArgGluLeuLeuPheGluThrSerGluValValAspValAlaLysLeu et ysAlaTyrIle SerMetlleValLysLysArgTyrSerThrThrArgSerAlaSerSerGlnGlySerSerArg (SEQ ID NO: 10). (GENBANK ACCESSION NO. NM_001743)

GGCACGAGGGCGCGGCGGAGCTGGAACTGCTGCAGCTGCTGCCGCCGCCGGAGGAACCTTGATCCCCGTGCTCCGGACACCCCGGG CCTCGCCATGGCTGACCAGCTGACTGAGGAGCAGATTGCAGAGTTCAAGGAGGCCTTCTCCCTCTTTGACAAGGATGGAGATGGCA

CTATCACCACCAAGGAGTTGGGGACAGTGATGAGATCCCTGGGACAGAACCCCACTGAAGCAGAGCTGCAGGATATGATCAATGA GGTGGATGCAGATGGGAACGGGACCATTGACTTCCCGGAGTTCCTGACCATGATGGCCAGAAAGATGAAGGACACAGACAGTGAG GAGGAGATCCGAGAGGCGTTCCGTGTCTTTGACAAGGATGGGAATGGCTACATCAGCGCCGCAGAGCTGCGTCACGTAATGACGAA CCTGGGGGAGAAGCTGACCGATGAGGAGGTGGATGAGATGATCAGGGAGGCTGACATCGATGGAGATGGCCAGGTCAATTATGAA GAGTTTGTACAGATGATGACTGCAAAGTGAAGGCCCCCCGGGCAGCTGGCGATGCCCGTTCTCTTGATCTCTCTCTTCTCGCGCGCG

CACTCTCTCTTCAACACTCCCCTGCGTACCCCGGTTCTAGCAAACACCAATTGATTGACTGAGAATCTGATAAAGCAACAAAAGATT TGTCCCAAGCTGCATGATTGCTCTTTCTCCTTCTTCCCTGAGTCTCTCTCCATGCCCCTCATCTCTTCCTTTTGCCCTCGCCTCTTCCAT CCATGTCTTCCAAGGCCTGATGCATTCATAAGTTGAAGCCCTCCCCAGATCCCCTTGGGGAGCCTCTGCCCTCCTCCAGCCCGGATG GCTCTCCTCCATTTTGGTTTGTTTCCTCTTGTTTGTCATCTTATTTTGGGTGCTGGGGTGGCTGCCAGCCCTGTCCCGGGACCTGCTGG GAGGGACAAGAGGCCCTCCCCCAGGCAGAAGAGCATGCCCTTTGCCGTTGCATGCAACCAGCCCTGTGATTCCACGTGCAGATCCC

AGCAGCCTGTTGGGGCAGGGGTGCCAAGAGAGGCATTCCAGAAGGACTGAGGGGGCGTTGAGGAATTGTGGCGTTGACTGGATGT GGCCCAGGAGGGGGTCGAGGGGGCCAACTCACAGAAGGGGACTGACAGTGGGCAACACTCACATCCCACTGGCTGCTGTTCTGAA ACCATCTGATTGGCTTTCTGAGGTTTGGCTGGGTGGGGACTGCTCATTTGGCCACTCTGCAGATTGGACTTGCCCGCGTTCCTGAAGC GCTCTCGAGCTGTTCTGTAAATACCTGGTGCTAACATCCCATGCCGCTCCCTCCTCACGATGCACCCACCGCCCTGAGGGCCCGTCC TAGGAATGGATGTGGGGATGGTCGCTTTGTAATGTGCTGGTTCTCTTTTTTTTTCTTTCCCCTCTATGGCCCTTAAGACTTTCATTTTG

TTCAGAACCATGCTGGGCTAGCTAAAGGGTGGGGAGAGGGAAGATGGGCCCCACCACGCTCTCAAGAGAACGCACCTGCAATAAA ACAGTCTTGTCGGCCAGCTGCCCAGGGGACGGCAGCTACAGCAGCCTCTGCGTCCTGGTCCGCCAGCACCTCCCGCTTCTCCGTGGT GACTTGGCGCCGCTTCCTCACATCTGTGCTCCGTGCCCTCTTCCCTGCCTCTTCCCTCGCCCACCTGCCTGCCCCCATACTCCCCCAG CCCTTTTCTGTTCATTTCATCTGGCTCCCCCCACCACCTCCCCACCCCACCCCCCACCCCCTGCTTCCCCTCACTGCCCAGGTCGATC

AAGTGGCTTTTCCTGGGACCTGCCCAGCTTTGAGAATCTCTTCTCATCCACCCTCTGGCACCCAGCCTCTGAGGGAAGGAGGGATGG

GGCATAGTGGGAGACCCAGCCAAGAGCTGAGGGTAAGGTCAGGTAGGCGTGAGGCTGTGGACATTTTCGGAATGTTTTGGTTTTGT

TTTTTTTAAACCGGGCAATATTGTGTTCAGTTCAAGCTGTGAAGAAAAATATATATCAATGTTTTCCAATAAAATACAGTGACTACCT

GAAAAAAAAAAAAAAAAAAA (SEQ ID NO: 11)

Amino acid sequence for Calmodulin 2 (GENBANKACCESSION No. NM_001743)

MθtAlaAspGln euThrGluGluGlnlleAlaGluPhe ysGluAlaPheSerLeuPheAspLysAspGlyAspGlyThrlleThrThrLysGluL euGlyThrValMetArgSerLeuGlyGlnAsnProThrGluAlaGluLeuGlnAspMetlleAsnGluValAspAlaAspGlyAsnGlyThrlleAs pPheProGluPheLeuThrMetMetAlaArgLysMetLysAspThrAspSerGluGluGluIleArgGluAlaPheArgValPheAspLysAspGly AsnGlyTyrlleSerAlaAlaGluLeuArgHisValMetThrAsn euGlyGluLysIjeuThrAspGluGluValAspGluMetlleArgGluAlaA spIleAspGlyAspGlyGlnValAsnTyrGluGluPheValGlnMetMetThrAla ys (SEQ ID NO: 12).

SEQ ID NO, GENBANK ACCESSION NO,, Length of oligo, Position of First nucleotide of oligo in target nucleic acid, Sequence of oligo

13,M5₅1₅3„20,3238,GGAATTGTGTATTGCAAACA„

14,M₅₅1₅3„20,3232,GTGTATTGCAAACATGGAGT„ 1₅,M₅₅1₅3„20,3226,TGCAAACATGGAGTGGAGAG„

16,M₅₅153„20,3220,CATGGAGTGGAGAGGATCCT„

17,M55153„20,3214,GTGGAGAGGATCCTTGGAGA„

18,M55153„20,32C)8,AGGATCCTTGGAGATGAGCA„

19,M5₅1₅3„20,3202,CTTGGAGATGAGCAGGTTCA„ 20,M5₅153„20,3196,GATGAGCAGGTTCAATCACT„

21 ,M55153„20,3190,CAGGTTCAATCACTCCTCTG„

22,M55153„20,3184,CAATCACTCCTCTGACCAAC„

23,M55153„20,3178,CTCCTCTGACCAACAAGGAA„

24,M55153„20,3172,TGACCAACAAGGAAACAAAG„ 25,M55153„20,3166,ACAAGGAAACAAAGGCCCAG„

26.M55153„20,3160,AAACAAAGGCCCAGAGAGGA„

27,M55153„20,31₅4,AGGCCCAGAGAGGAGAAGGC„

28,M55153„20,3148,AGAGAGGAGAAGGCAGTCGC„

29,M55153„20,3142,GAGAAGGCAGTCGCTGGCCA„ 30,M55153„20,3136,GCAGTCGCTGGCCAGACGTG„

31,M55153„20,3130,GCTGGCCAGACGTGGGACCT„

32,M5₅153„20,3124,CAGACGTGGGACCTGAACCC„

33,M5₅1₅3„20,3118,TGGGACCTGAACCCAGCCAG„

34,M5₅153„20,3112,CTGAACCCAGCCAGGGCTCT„ 35,M5₅1₅3„20,3106,CCAGCCAGGGCTCTGACTCC„

36.M551₅3„20,3100,AGGGCTCTGACTCCCAGTCC„

37,M55153„20,3094,CTGACTCCCAGTCCCCCAGT„

38,M55153„20,3088,CCCAGTCCCCCAGTCCCCTC„

39.M55153„20,3082,CCCCCAGTCCCCTCTCTACC„ 40,M5₅153„20,3076,GTCCCCTCTCTACCTCCTTG„

41 ,M55153„2^Q,3070,TCTCTACCTCCTTGTCTTGG„

42.M55153„20,3064,CCTCCTTGTCTTGGCTGAGT„

43,M55153„20,30₅8,TGTCTTGGCTGAGTCTTTTT„

44,M5₅153„20,3052,GGCTGAGTCTTTTTTTGATA„ 45,M5₅153„20,304₆,GTCTTTTTTTGATAAAGGCC„

46,M5₅153„20,3₀40,TTTTGATAAAGGCCCCAGAC„

47,M55153„20,3034,TAAAGGCCCCAGACAGCCTC„

48.M55153„20,3028,CCCCAGACAGCCTCTGCGAC„

49,M55153„20,3022,ACAGCCTCTGCGACAGTCTC„ 50,M55153„20,3016,TCTGCGACAGTCTCAGGTCA„ 51 ,M₅₅153„20,3010,ACAGTCTCAGGTCAGGCTGG„

₅2,M₅₅153„20,3004,TCAGGTCAGGCTGGGGTTAT„

₅3,M5₅153„20,2998,CAGGCTGGGGTTATAAATGG„

54,M₅₅153„20,2992,GGGGTTATAAATGGAGCAGT„ 5₅,MS5153„20,2986,ATAAATGGAGCAGTGGACTC„

56,M₅₅153„20,2980,GGAGCAGTGGACTCAGAGTC„

57,M₅₅153„20,2974,GTGGACTCAGAGTCAGAGGC„

₅8,M₅₅153„20,2968,TCAGAGTCAGAGGCCCAGAC„

₅9,M₅5153„20,2962,TCAGAGGCCCAGACTCTGCT„ 60,M55153„20,2956,GCCCAGACTCTGCTCTTGGG„

61,M551₅3„20_J2950,ACTCTGCTCTTGGGCCTTCA„

62.M55153„2₀,2944,CTCTTGGGCCTTCACATTAC„

63,M5S153„2₀,2938,GGCCTTCACATTACCCAGCC„

64,M55153„20,2932,CACATTACCCAGCCTTGCTT„ 6₅,M₅5153„20,2926,ACCCAGCCTTGCTTATAACC„

66,M₅5153„20,2920,CCTTGCTTATAACCACGAGG„

67_>M₅₅153„2^Q,2914,TTATAACCACGAGGCCACTG„

68,M₅₅153„20,2908,CCACGAGGCCACTGGTGTGG„

69,M₅₅153„20,2902,GGCCACTGGTGTGGAGGGGG„ 70,M5₅153„20,2896,TGGTGTGGAGGGGGCTGCCT„

71,M55153„20,2890,GGAGGGGGCTGCCTCCTCTC„

72,M5₅153„20,2884,GGCTGCCTCCTCTCTCTAAG„

73,M55153„20,2878,CTCCTCTCTCTAAGCCTCAG„

74,M5₅153„20,2872,TCTCTAAGCCTCAGTCTCCT„ 75,M55153„20,2866AGCCTCAGTCTCCTTATCCT„

76,M₅₅153„20,2860,AGTCTCCTTATCCTGGAAGC„

77,MS5153„20,2854_JCTTATCCTGGAAGCAGCGCC„

78,M₅₅153„20,2848,CTGGAAGCAGCGCCCACAAC„

79,M₅₅153„20,2842,GCAGCGCCCACAACAGTTTC„ 80_JM₅₅153„20,2836_>CCCACAACAGTTTCCCATGG„

81_>M₅5153„20,2830,ACAGTTTCCCATGGTGATTA„

82,M₅₅153„20,2824,TCCCATGGTGATTAAATGGG„

83,M₅₅153„20,2818,GGTGATTAAATGGGTTGGAG„

84,M₅₅153„20,2812,TAAATGGGTTGGAGGCCCCG„ 8₅,M₅₅153„20,2806,GGTTGGAGGCCCCGTGAGCC„

86,M₅₅153„20,280Q,AGGCCCCGTGAGCCCCAGCA„

87,M55153„20,2794,CGTGAGCCCCAGCAAGTGTG„

88,M55153„20,2788,CCCCAGCAAGTGTGGGAGGC„

S9,M₅5153„20,2782,CAAGTGTGGGAGGCACCCAG„ 90,M₅5153„20,2776,TGGGAGGCACCCAGCACATA„

91,M55153„20,2770,GCACCCAGCACATAGTAGGT„

92,M₅51₅3„20,2764,AGCACATAGTAGGTGCTTCA„

93,M₅5153„20,27₅8,TAGTAGGTGCTTCACAATGG„

94,M₅51₅3„20,27₅2,GTGCTTCACAATGGTGAGGT„ 95,M₅₅1₅3„20,2746,CACAATGGTGAGGTTGAGGG„

96,M₅₅1₅3„2_0l2740,GGTGAGGTTGAGGGGGAGGG„

97,M₅₅1₅3„20,2734,GTTGAGGGGGAGGGCTATTA„

98,M₅₅1₅3„20,2728,GGGGAGGGCTATTAAGCTTG„

99,M5₅1₅3„20,2722,GGCTATTAAGCTTGGGCTGC„ 100,M₅₅1₅3„20,2716,TAAGCTTGGGCTGCTGGGAT„

101 ,M55153„20,2710,TGGGCTGCTGGGATGTGGAG„

102,M₅₅1₅3„20,2704,GCTGGGATGTGGAGGGGACC„

103,M₅₅1₅3„20,2698,ATGTGGAGGGGACCTTGGGC„

104,M₅₅1₅3„20,2692,AGGGGACCTTGGGCCTATCA„ 10₅,M₅51₅3„20,2686,CCTTGGGCCTATCACTGTCC„

106,M5₅153„2₀₎2680,GCCTATCACTGTCCCCACCC„

107,M55153„20,2674,CACTGTCCCCACCCAGCTCT„

1Q8,M55153„20,2668,CCCCACCCAGCTCTGGGTGT„

109,M55153„20,2662,CCAGCTCTGGGTGTCCCAAG„ 110,M55153„20,2656,CTGGGTGTCCCAAGGGCCCC„

111.M55153„20,2650,GTCCCAAGGGCCCCTGGAGC„

112,M55153„20,2644,AGGGCCCCTGGAGCTGGGTG„

113,M55153„20,2638,CCTGGAGCTGGGTGCAGTCA„

114.M55153„20,2632,GCTGGGTGCAGTCATGGGAA„ 11₅,M55153„20,262₆,TGCAGTCATGGGAAGAGGTA„

116.M55153„20,2620,CATGGGAAGAGGTACGGGAT„

117,M55153„20,2614,AAGAGGTACGGGATGCAGTC„

118,M55153„20,2608,TACGGGATGCAGTCTAGGGA„

119,M55153„20,2602,ATGCAGTCTAGGGAGCTGGA„ 120,M55153„20,2₅96,TCTAGGGAGCTGGATTCCTG„

121,M55153„20,2590,GAGCTGGATTCCTGATCCAG„

122,M55153„20,2₅84,GATTCCTGATCCAGCCAAGG„

123,M₅5153„20,2₅78,TGATCCAGCCAAGGGCATGC„

124,M₅₅1₅3„20,2₅72,AGCCAAGGGCATGCTGTCCC„ 125,M₅₅1₅3„20,2₅66,GGGCATGCTGTCCCTTTTTT„ 126,M55153„20,2560,GCTGTCCCTTTTTTGCCTGC„

127,M55153„20,2554,CCTTTTTTGCCTGCTCCAAG„

128,M₅₅1₅3„20,2548,TTGCCTGCTCCAAGGAGCTA„

129,M₅₅1₅3„20,2542,GCTCCAAGGAGCTATGAAGT„ 130,M₅51₅3„20,2536,AGGAGCTATGAAGTAGATCA„

131 ,M551₅3„20,2₅30,TATGAAGTAGATCAAACAAT„

132.M55153„20,2524,GTAGATCAAACAATATGGTG„

133.M55153„20,2518,CAAACAATATGGTGGGTGGT„

134,M55153„20,2512,ATATGGTGGGTGGTCAATGG„ 135.M55153„20,2506,TGGGTGGTCAATGGCTTTCC„

136,M55153„20,2500,GTCAATGGCTTTCCAAAGGG„

137,M55153„20,2494,GGCTTTCCAAAGGGCATCTG„

138,M55153„20,2488,CCAAAGGGCATCTGGGCAGG„

139,M55153„20,2482,GGCATCTGGGCAGGAGAGGG„ 140,M₅5153„20,2476,TGGGCAGGAGAGGGAATGTA„

14LM55153„20,2470,GGAGAGGGAATGTAGGTCTT„

142,M₅₅153„20,2464,GGAATGTAGGTCTTTCCTCT„

143,M55153„20,24₅8,TAGGTCTTTCCTCTCTCACC„

144,M₅₅153„20,24₅2,TTTCCTCTCTCACCCCAGCC„ 14₅,M₅₅153„20,244₆,CTCTCACCCCAGCCCCAGTC„

146,M₅₅1₅3„20,2440,CCCCAGCCCCAGTCAGCACA„

147,M5₅1₅3„20,2434,CCCCAGTCAGCACAGGTCAG„

148,M5₅1₅3„20,2428,TCAGCACAGGTCAGGGCTCC„

149,M5₅1₅3„20,2422,CAGGTCAGGGCTCCCACTGT„ 1₅₀,M5₅153„20,2416,AGGGCTCCCACTGTTTCTGG„

151,M55153„20,2410,CCCACTGTTTCTGGCACAGA„

1₅2,M₅₅1₅3„20,2404,GTTTCTGGCACAGAGCATTC„

1₅3,M₅₅1₅3„20,2398,GGCACAGAGCATTCCTCACA„

154,M₅₅1₅3„20,2392,GAGCATTCCTCACAGCAAAG„ 155,M55153„2₀,2386,TCCTCACAGCAAAGGGGGTG„

1₅₆,M55153„20,2380,CAGCAAAGGGGGTGAGTGGG„

1₅7,M₅5153„20,2374,AGGGGGTGAGTGGGGACCCA„

1₅8,M₅₅1₅3„20,2368,TGAGTGGGGACCCACAGGCT„

1₅9,M₅51₅3„20,2362,GGGACCCACAGGCTCAGGAG„ 1₆0,M₅51₅3„20,23₅6,CACAGGCTCAGGAGGCTGAG„

161,M55153„20,2350,CTCAGGAGGCTGAGATGGGC„

162,M55153„20,2344,AGGCTGAGATGGGCCAGGGG„

163,M55153„20,2338,AGATGGGCCAGGGGCACATT„

1₆4_;M₅5153„2₀,2332,GCCAGGGGCACATTCCATTT„ 1₆5,M₅5153„20,2326,GGCACATTCCATTTCCGAGA„

166,M₅5153„20,2320,TTCCATTTCCGAGAGCCCCC„

167.M55153„20,2314,TTCCGAGAGCCCCCATAGGC„

168,M₅₅153„20,2308,GAGCCCCCATAGGCTGCCCA„

169.M55153„20,2302,CCATAGGCTGCCCACCCTGC„ 170,M₅₅153„20,2296,GCTGCCCACCCTGCCCTGGG„

171,M55153„20,2290,CACCCTGCCCTGGGGTCTGG„

172,M5₅153„20,2284,GCCCTGGGGTCTGGGGCCCA„

173,M55153„20,2278,GGGTCTGGGGCCCAATAAGG„

174,M5₅153„20,2272,GGGGCCCAATAAGGGGCATA„ 17₅,M5₅153„20,22₆₆,CAATAAGGGGCATATTTTGC„

176.M55153„20,2260,GGGGCATATTTTGCTCACTA„

177,M55153„20,2254,TATTTTGCTCACTAGCTTGG„

178,M5₅153,,20,2248,GCTCACTAGCTTGGGATAAG„

179,M5₅1₅3„20,2242,TAGCTTGGGATAAGGATTGG„ 180,M₅51₅3„20,2236,GGGATAAGGATTGGGATCAA„

181 ,M551₅3„20,2230,AGGATTGGGATCAAGGTGGG„

182,M₅51₅3„20,2224,GGGATCAAGGTGGGGGCTCT„

183,M₅51₅3„20,2218,AAGGTGGGGGCTCTCAGCAG„

184,M551₅3„20,2212,GGGGCTCTCAGCAGGCTGGG„ 185,M55153„20,2206,CTCAGCAGGCTGGGAGCAGG„

186,M551S3„20,2200,AGGCTGGGAGCAGGGGTCCC„

187.M55153„20,2194,GGAGCAGGGGTCCCTTAGGC„

188,M55153„20,2188,GGGGTCCCTTAGGCGGGGCC„

189.M551₅3„20,2182,CCTTAGGCGGGGCCAATGAT„ 190.M55153„20,2176,GCGGGGCCAATGATGACATT„

191,M55153„20,2170,CCAATGATGACATTCCGGAA„

192,M₅51₅3„20,21₆4,ATGACATTCCGGAAGCCCTT„

193,M₅51₅3,,20,2158,TTCCGGAAGCCCTTCACAGC„

194,M₅5153„20,21₅2,AAGCCCTTCACAGCCTTCAG„ 195,M₅5153„20,2146,TTCACAGCCTTCAGCTTGTC„

196,M55153„20,2140,GCCTTCAGCTTGTCGCTCTC„

197,M55153„20,2134,AGCTTGTCGCTCTCGAAGTT„

198,M5₅153„20,2128/TCGCTCTCGAAGTTCACCAC,,

199,M5₅153„20,2122,TCGAAGTTCACCACCAGCTT„ 200,M5₅153„20,2116,TTCACCACCAGCTTGTGGAG„ 201,M55153„20,2110,ACCAGCTTGTGGAGGCCCAT„

202,M₅51₅3„20,2104_JTTGTGGAGGCCCATGTGGAG„

203,M₅₅1₅3„20,2098,AGGCCCATGTGGAGCGGCAC„

204.M55153„20,2092,ATGTGGAGCGGCACGAGGTC„ 205,M₅₅153„20,2Q86,AGCGGCACGAGGTCCATTCT„

206,M₅₅153„20,2080,ACGAGGTCCATTCTCACCTT„

207,M55153„20,2074,TCCATTCTCACCTTAACTTC„

208,M₅₅1₅3„20,2068,CTCACCTTAACTTCCTCCCC„

209,M₅51₅3„20,2062,TTAACTTCCTCCCCTGCCTC„ 210,M551₅3„20₎2₀₅6_>TCCTCCCCTGCCTCCACGGG„

211 ,M551₅3„20,2₀₅0,CCTGCCTCCACGGGGTCTGG„

212,M55153„20,2044,TCCACGGGGTCTGGGATCTC„

213,M55153„20,2038,GGGTCTGGGATCTCCACCGT„

214,M551₅3„20,2032,GGGATCTCCACCGTCTTCTG„ 215,M₅51₅3„20,2026,TCCACCGTCTTCTGCTCCTC„

216,M₅51₅3„20,2020,GTCTTCTGCTCCTCAGTCAG„

217_>M₅51₅3„20,2014,TGCTCCTCAGTCAGGCCGGC„

218,M₅51₅3„20,2008,TCAGTCAGGCCGGCCCCCTC„

219,M₅51₅3„20,2002,AGGCCGGCCCCCTCCACAGT„ 220,M551₅3„20, 1996,GCCCCCTCCACAGTGAAGGT„

221 ,M₅51₅3„20, 1990,TCCACAGTGAAGGTGCAGCC„

222,M₅51₅3„20, 1984,GTGAAGGTGCAGCCTTCCAG„

223,M₅5153„20,1978,GTGCAGCCTTCCAGGGCCAC„

224.M55153„20, 1972,CCTTCCAGGGCCACAGGGAG„ 225,M₅₅1₅3„20,1966,AGGGCCACAGGGAGCGGGTT„

226,M₅₅1₅3„20, 1960,ACAGGGAGCGGGTTCTGCAG„

227,M₅₅1₅3„20,19₅4,AGCGGGTTCTGCAGGGACAC„

228,M₅₅1₅3„20,1948,TTCTGCAGGGACACCTCAGC„

229,M₅₅153„20,1942,AGGGACACCTCAGCCACCAG„ 230,M₅₅1₅3„20, 1936,ACCTCAGCCACCAGCTTGCG„

231 ,M₅₅1₅3„20, 1930,GCCACCAGCTTGCGTTTCTG„

232,M₅51₅3„20, 1924.AGCTTGCGTTTCTGCTTGGG,,

233.M55153„20, 1918,CGTTTCTGCTTGGGCTCCCC„

234,M₅51₅3„20,1912,TGCTTGGGCTCCCCAAGGAT„ 235,M₅₅1₅3„20,1906,GGCTCCCCAAGGATCCGGAT„

236,M₅₅153„20_;19Q0,CCAAGGATCCGGATCTTGAT„

237,M₅₅153„20, 1894,ATCCGGATCTTGATTTCTGG„

238,M551₅3„20,1888,ATCTTGATTTCTGGATTCTC„

239,M5₅153„20, 1882.ATTTCTGGATTCTCCAGGTA,, 240,M55153„2₀₎ 1876,GGATTCTCCAGGTAGAGGTC„

241 ,M55153„20, 1870,TCCAGGTAGAGGTCCCTCTC„

242,M55153„20, 1864,TAGAGGTCCCTCTCAGCCAG„

243,M551₅3„20,1858,TCCCTCTCAGCCAGCAGGTA„

244,M55153„2Q,1852,TCAGCCAGCAGGTAGCTGTT„ 245.M551₅3„20, 184₆,AGCAGGTAGCTGTTGATAAC„

246,M₅51₅3„2Q, 1840,TAGCTGTTGATAACTGGCTC„

247,M₅5153„20, 1834,TTGATAACTGGCTCCACGAG„

248,M551₅3„20, 1828,ACTGGCTCCACGAGGAGGGC„

249,M55153„20, 1822,TCCACGAGGAGGGCCCGCAC„ 250,M₅51₅3„20, 1816,AGGAGGGCCCGCACCTTGAT„

2₅1 ,M₅51₅3„20, 1810,GCCCGCACCTTGATGAGGTT„

2₅2,M₅₅1₅3„20, 1804,ACCTTGATGAGGTTGGACTC„

2₅3,M₅51₅3„20, 1798.ATGAGGTTGGACTCCGTAAG,,

2₅4,M551₅3„20,1792,TTGGACTCCGTAAGGCAGTC„ 2₅₅₎M551₅3„20,1786,TCCGTAAGGCAGTCACGGTA„

2₅6,M₅51₅3„20,1780,AGGCAGTCACGGTATTTCTC„

2₅7,M₅₅1₅3„20,1774,TCACGGTATTTCTCATAGAG„

2₅8,M5₅1₅3„20,1768,TATTTCTCATAGAGGATGCA„

2₅9,M551₅3„20,1762,TCATAGAGGATGCAAAGAGG„ 260,M5₅1₅3„20,1756,AGGATGCAAAGAGGAACGCT„

261,M5₅1₅3„20,1750,CAAAGAGGAACGCTCTTCTC„

2₆2,M551₅3„20,1744,GGAACGCTCTTCTCAGAGAA„

2₆3,M551₅3„2Q,1738,CTCTTCTCAGAGAAAGGCTC„

2₆4,M551₅3„20,1732,TCAGAGAAAGGCTCCAGGGT„ 2₆₅,M551₅3„20,172₆,AAAGGCTCCAGGGTTAGGTT„

266,M55153„20,1720,TCCAGGGTTAGGTTGAGCAG„

267, 55153„2Q,1714,GTTAGGTTGAGCAGGTACTT„

2₆8,M5₅1₅3„20,1708,TTGAGCAGGTACTTGGTGCC„

2δ9,M5₅l₅3„20,1702,AGGTACTTGGTGCCACACTC„ 270,M5₅1₅3„20, 1696,TTGGTGCCACACTCGGGCCC„

271 ,M551₅3„20, 1690,CCACACTCGGGCCCCAAGAT„

272.M55153„20, 1684,TCGGGCCCCAAGATCCCATT„

273,M551₅3„20,1678,CCCAAGATCCCATTGTAGCT„

274,M55153„20, 1672,ATCCCATTGTAGCTGACGGT„ 27₅,M55153„20, 1₆66,TTGTAGCTGACGGTGCGGGC„ 276,M₅₅1₅3 ', 1660,CTGACGGTGCGGGCACAGAG„ 277,M₅51₅3_i 1654,GTGCGGGCACAGAGCAGGAG„ 278,M55153_: i, 1648,GCACAGAGCAGGAGGCGGCA„ 279,M55153 i, 1642,AGCAGGAGGCGGCAGACGTA„ 280.M55153 ',1636, AGGCGGCAGACGTACTCCTC,, 281.M55153 ', 1630,CAGACGTACTCCTCAGCGGT„ 282,M5₅153_: , 1624,TACTCCTCAGCGGTGTTGTT„ 283,M₅₅153_: , 1618,TCAGCGGTGTTGTTGGTGAT„ 284,M₅5153. U612,GTGTTGTTGGTGATGTGGGC„ 285,M55153, 16Q6,TTGGTGATGTGGGCAAAGAC„ 286,M₅₅153 ', 1600,ATGTGGGCAAAGACGTCAAA„ 287,M5₅153_: , 1594,GCAAAGACGTCAAAGTCACT„ 288,M5₅153_: , 1₅88,ACGTCAAAGTCACTGCCCAT„ 289,M55153_: , 1₅82,AAGTCACTGCCCATGTTCAT„ 290,M₅₅1₅3_; , 1576,CTGCCCATGTTCATGCTCTG„ 291.M55153 , 1570,ATGTTCATGCTCTGGCCCAC„ 292.M55153 , 1564,ATGCTCTGGCCCACACGGAT„ 293,M55153 , 1₅₅8,TGGCCCACACGGATCCGCAT„ 294,M55153_; , 1₅52,ACACGGATCCGCATGGCCAT„ 29₅,M55153_: , 1546,ATCCGCATGGCCATCCCTGT„ 296,M55153 , 1540,ATGGCCATCCCTGTCTCCTC„ 297,M551₅3 ', 1534,ATCCCTGTCTCCTCCTTCTC„ 298,M55153 ', 1528,GTCTCCTCCTTCTCGGCCAG„ 299.M55153 ^■, 1522,TCCTTCTCGGCCAGTTTGTT„ 300,M55153, ,1516,TCGGCCAGTTTGTTCAGGTG„ 301.M55153 ■,T 510,AGTTTGTTCAGGTGGTTCGC„ 302,M₅₅1₅3 ', 1504,TTCAGGTGGTTCGCCCTTGT„ 303,M₅51₅3 1498,TGGTTCGCCCTTGTGAAGGC„ 304.M55153 ', 1492,GCCCTTGTGAAGGCCTCCCT„ 305,M551₅3 ,1486,GTGAAGGCCTCCCTCTCCTC„ 306.M551S3 ι,1480,GCCTCCCTCTCCTCTGAGGA„ 307,M₅₅153 ',1474,CTCTCCTCTGAGGACCCCTC„ 308,M₅₅1₅3 ', 1468,TCTGAGGACCCCTCTGGGTA„ 309,M₅₅1₅3 ,1462,GACCCCTCTGGGTATTTGTA„ 310,M₅₅1₅3 ', 1456,TCTGGGTATTTGTAGGTGTG„ 311.M55153. , 1450,TATTTGTAGGTGTGGGTGAT„ 312.M55153 ,1444,TAGGTGTGGGTGATATCCTC„ 313,M55153 ,1438,TGGGTGATATCCTCCCGCTC„ 314,M5₅153 >,1432,ATATCCTCCCGCTCGTCTCG„ 315,M₅₅1₅3 ', 1426,TCCCGCTCGTCTCGGCCCAC„ 316,M₅₅1₅3. , 1420,TCGTCTCGGCCCACGCTCTT„ 317,M₅₅1₅3. ,1414,CGGCCCACGCTCTTAGTGCT„ 318,M55153_: , 1408,ACGCTCTTAGTGCTGATCTT„ 319,M55153 ,1402,TTAGTGCTGATCTTCAGCCC„ 320,M55153 ,1396,CTGATCTTCAGCCCAACGAT„ 321,M55153_: , 1390,TTCAGCCCAACGATCAGGGA„ 322,M₅₅1₅3_; , 1384,CCAACGATCAGGGAACGGTT„ 323,M₅₅1₅3_; , 1378,ATCAGGGAACGGTTGATGGA„ 324,M₅5153_; , 1372,GAACGGTTGATGGATTTGTG„ 325,M₅51₅3, ,1366,TTGATGGATTTGTGCACAGA„ 326,M₅₅153_: , 1360,GATTTGTGCACAGACCCATC„ 327,M₅₅1₅3_; , 1354,TGCACAGACCCATCGTCCTG„ 328,M₅51₅3_: , 1348,GACCCATCGTCCTGCTGGAT„ 329,M₅5153_; , 1342,TCGTCCTGCTGGATCCAGTC„ 330,M₅₅153 ,1336,TGCTGGATCCAGTCTACCAC„ 331,M55153_; ^■, 1330,ATCCAGTCTACCACGTCGGC„ 332,M5₅153_: ,1324,TCTACCACGTCGGCATTGAC„ 333,M₅5153_; ,1318 ,ACGTCGGCATTGACCTCCGC„ 334,M₅51₅3_; ,1312,GCATTGACCTCCGCAAAGAC„ 335,MS5153 ,1306,ACCTCCGCAAAGACAAAGGG„ 336,M55153_: ^■, 1300,GCAAAGACAAAGGGCGCATC„ 337.M55153 ,1294,ACAAAGGGCGCATCGTACTT„ 33S,M₅5153_: ,1288,GGCGCATCGTACTTGGTGCT„ 339,M₅₅153_: ,1282,TCGTACTTGGTGCTCAGGTC„ 340,M5₅1₅3 ',1276,TTGGTGCTCAGGTCGCCCTC„ 341.M55153 i, 1270,CTCAGGTCGCCCTCCTTGAT„ 342,M₅₅1₅3 ', 1264,TCGCCCTCCTTGATGGCACG„ 343,M₅5153 ,1258,TCCTTGATGGCACGAACTGG„ 344,M55153 ', 1252,ATGGCACGAACTGGAACTGG„ 345,M55153 ',1246,CGAACTGGAACTGGGCCACA„ 346,M55153 ,1240,GGAACTGGGCCACAGCAGTA„ 347,M5₅153 ', 1234,GGGCCACAGCAGTACGTTCC„ 348,M5₅153 1228,CAGCAGTACGTTCCTTCGCT„ 349.M55153 ι,1222,TACGTTCCTTCGCTCTTCTC„ 3₅0,M55153 1216,CCTTCGCTCTTCTCCTGGGG„ 351.M55153„20, 121 O.CTCTTCTCCTGGGGCGTTGG,,

352,M55153„20,1204,TCCTGGGGCGTTGGGTCCAG„

3₅3,M5₅1₅3„20,1198,GGCGTTGGGTCCAGGGCCTG„

354,M₅51₅3„20, 1192,GGGTCCAGGGCCTGCCAGCC„ 355,M551S3„20,H86,AGGGCCTGCCAGCCCTCGTA„

356.M55153„20, 1180,TGCCAGCCCTCGTACCCCGG„

357,M₅5153„20,1174,CCCTCGTACCCCGGCTGCAG„

3₅8,M₅₅1₅3„20,1168,TACCCCGGCTGCAGGTCCGG„

3₅9,M551₅3„20, 1162,GGCTGCAGGTCCGGCCTGGT„ 360,M55153„20, 1156,AGGTCCGGCCTGGTCATCCA„

361 ,M55153„20, 1150,GGCCTGGTCATCCACGACTC„

362,M₅51₅3„20,1144,GTCATCCACGACTCCACCCA„

363,M₅5153„20,1138,CACGACTCCACCCAGCAGTG„

364,M5₅153„20, 1132,TCCACCCAGCAGTGGAAGTT„ 365,M55153„20,1126,CAGCAGTGGAAGTTCCAGAT„

366.M55153„20, 1120,TGGAAGTTCCAGATCATCTC„

367,M55153„20,1114,TTCCAGATCATCTCGCTCTT„

368,M55153„20,1108,ATCATCTCGCTCTTGTCACC„

369,M55153„20, 1102,TCGCTCTTGTCACCCTGGAT„ 370,M55153„20,1096,TTGTCACCCTGGATCTCCCC„

371,M55153„20,1090,CCCTGGATCTCCCCAAACTC„

372,M55153„20,1084,ATCTCCCCAAACTCATTGCG„

373,M55153„20,1Q78,CCAAACTCATTGCGGAAGTA„

374,M55153„20,1072,TCATTGCGGAAGTACTCGAT„ 375,M5₅1₅3„20,1066,CGGAAGTACTCGATGAGAAG„

376,M5₅1₅3„20, 1060,TACTCGATGAGAAGGTTGCT„

377,M₅₅1₅3„20, 1054,ATGAGAAGGTTGCTGTTCTG„

378,M55153„20,1048,AGGTTGCTGTTCTGGTCATG„

379,M55153„20,1042,CTGTTCTGGTCATGGGCCGA„ 380,M55153„20,1036,TGGTCATGGGCCGAGTTGTA„

381,M55153„20,1030,TGGGCCGAGTTGTAGTTGGT„

382.M55153„20, 1024,GAGTTGTAGTTGGTCACGAC„

383,M55153„20,1018,TAGTTGGTCACGACGCGGGT„

384,M55153„20,1012,GTCACGACGCGGGTAGGGAT„ 385,M55153„20,1006,ACGCGGGTAGGGATGCCTAG„

386,M55153„20,1000,GTAGGGATGCCTAGGCACCT„

387,M55153„20,994,ATGCCTAGGCACCTCAGCAC„

388.M55153„20,988,AGGCACCTCAGCACTGTGCA„

389.M55153„20,982,CTCAGCACTGTGCAGGCCAC„ 390,M55153„2(),976,ACTGTGCAGGCCACGGCGGC„

391,M55153„20,970,CAGGCCACGGCGGCGAAGAC„

392,M55153„20,964,ACGGCGGCGAAGACCCAGCA„

393,M55153„2₀,958,GCGAAGACCCAGCACTGGCC„

394,M55153„20,952,ACCCAGCACTGGCCATACTT„ 395,M55153„20,946,CACTGGCCATACTTGACGCG„

396,M551₅3„2Q,940,CCATACTTGACGCGCTGGCA„

397.M55153„20,934,TTGACGCGCTGGCAGCCGTG„

398,M55153„20,928,CGCTGGCAGCCGTGGTTCTT„

399,M55153„20,922,CAGCCGTGGTTCTTCCAGCG„ 400,M55153„20,916,TGGTTCTTCCAGCGCCGCAG„

401,M55153„20,910,TTCCAGCGCCGCAGGATGTC„

402,M551₅3„20,904,CGCCGCAGGATGTCCACGCT„

403,M5₅1₅3„20,898_JAGGATGTCCACGCTGCCGAT„

404,M₅₅1₅3„20,892,TCCACGCTGCCGATCCAGGA„ 40₅,M₅5153„20,886,CTGCCGATCCAGGACATGGG„

406,M55153„20,880,ATCCAGGACATGGGGCTGAC„

407.M55153„20,874,GACATGGGGCTGACGCCGTC„

408,M55153„20,868,GGGCTGACGCCGTCCCCGTA„

409.M55153„20,862,ACGCCGTCCCCGTAGTTGTT„ 41₀,M5₅1₅3„20,8₅6,TCCCCGTAGTTGTTGTCCCA„

411 ,M5₅1₅3„20,850_;TAGTTGTTGTCCCAGCGTCC„

412,M551₅3„20,844,TTGTCCCAGCGTCCCAGCAG„

413,M55153„20,838,CAGCGTCCCAGCAGCACACC„

414,M55153„20,832,CCCAGCAGCACACCCTGGTC„ 415,M₅5153„20,826,AGCACACCCTGGTCATCGTT„

416,M551₅3„20,820,CCCTGGTCATCGTTGCAGTT„

417,M5₅1₅3„20,814,TCATCGTTGCAGTTGACCAT„

418,M5₅1₅3„20,808,TTGCAGTTGACCATGCCACT„

419,M5₅1₅3„20,802,TTGACCATGCCACTACCCAC„ 420,M551₅3„20,796,ATGCCACTACCCACCCGGCC„

421 ,M551 S3„20,790,CTACCCACCCGGCCCACGTA„

422,M55153„20,784,ACCCGGCCCACGTAGACGGG„

423,M55153„20,778,CCCACGTAGACGGGGCTGCT„

424,M55153„20,772,TAGACGGGGCTGCTGCGCCG„ 425,M₅5153„20,766,GGGCTGCTGCGCCGGGAGCA„ 426,M₅5153„20,760,CTGCGCCGGGAGCAGTCACG„ 427.M55153„20,754,CGGGAGCAGTCACGGCCGGC„ 428,M55153„20,748,CAGTCACGGCCGGCGTTCTT„ 429,M 55153„20,742,CGGCCGGCGTTCTTCAGGAA„ 430,M55153„20,736,GCGTTCTTCAGGAACTTGGG„

431 ,M55153„20,730,TTCAGGAACTTGGGGTTGAC„ 432,M551₅3„20,724,AACTTGGGGTTGACATCTAG„ 433,M₅5153„20,718,GGGTTGACATCTAGAAGGAT„ 434,M₅5153„20,712,ACATCTAGAAGGATCAGGCA„ 43₅,M₅5153„20,706,AGAAGGATCAGGCAGATGTC„

436,M55153„20,700,ATCAGGCAGATGTCTAGGAT„ 437,M55153„20,694,CAGATGTCTAGGATCCCATC„ 438,M5₅153„20,688,TCTAGGATCCCATCTTGAAA„ 439_IM55153„20,682,ATCCCATCTTGAAACTGCCC„ 440,M5₅153„20,676,TCTTGAAACTGCCCAAAATT„

441,M55153„20₎670,AACTGCCCAAAATTCCAAGG„ 442.M55153„20,664,CCAAAATTCCAAGGTATGTT„ 443,M55153„20,658,TTCCAAGGTATGTTCTTGAT„ 444,M5₅153„20,652,GGTATGTTCTTGATGAACTT„ 445,M55153„20,64₆₎TTCTTGATGAACTTGGCCGA„

446,M55153„20,640,ATGAACTTGGCCGAGCCCTG„ 447,M55153„20,634,TTGGCCGAGCCCTGGTAGAT„ 448,M55153„20,628,GAGCCCTGGTAGATAAAGCC„ 449,M55153„20,622,TGGTAGATAAAGCCCTGCTG„ 450,M55153„20,616,ATAAAGCCCTGCTGGGTGAG„

451,M55153„20,610,CCCTGCTGGGTGAGGACATA„ 452,M55153„20,604,TGGGTGAGGACATACTCCTG„ 453,M55153„20,598,AGGACATACTCCTGCCGCTC„ 454,M55153„20,592,TACTCCTGCCGCTCCTCTTC„ 455,M551₅3„20,₅86,TGCCGCTCCTCTTCCGAGTC„

456,M551₅3„20₎₅80,TCCTCTTCCGAGTCCAGGTA„ 4₅7,M₅5153„20,574,TCCGAGTCCAGGTACACAGC„ 458,M55153„20,568,TCCAGGTACACAGCATCCGC„ 459, 55153„20,562,TACACAGCATCCGCTGGGCA„ 460,M55153„20,556,GCATCCGCTGGGCACCAGGC„

461 ,M5₅153„20_j550,GCTGGGCACCAGGCGTTGAA„ 462.M55153„20,544,CACCAGGCGTTGAAGAGCAA„ 463,MS51S3„20,₅38,GCGTTGAAGAGCAAAATGAA„ 464,M55153„20,532,AAGAGCAAAATGAAGTGGCC„ 465,M55153„20,526,AAAATGAAGTGGCCCAGCAC„

466,M55153„20,520,AAGTGGCCCAGCACAAAGCT„ 467,M55153„20,514,CCCAGCACAAAGCTGGATCC„ 468,M55153„20,508,ACAAAGCTGGATCCCTGGTA„ 469,M55153„20,502,CTGGATCCCTGGTAGCCAGT„ 470,M55153„20,496,CCCTGGTAGCCAGTGGAGGC„

471 ,M55153„20,490,TAGCCAGTGGAGGCCTCCAG„ 472,M55153„20,484,GTGGAGGCCTCCAGGCTGAG„ 473,M55153„20,478,GCCTCCAGGCTGAGGCGATA„ 474,M55153„20,472,AGGCTGAGGCGATACAGGCC„ 475,M551₅3„20,466,AGGCGATACAGGCCGATGGG„

476.M551₅3„20,460,TACAGGCCGATGGGGGCGTT„ 477.M55153„20,454,CCGATGGGGGCGTTGGCCGG„ 478.M551₅3„20,448,GGGGCGTTGGCCGGGGTGGT„ 479,M₅51₅3„20,442,TTGGCCGGGGTGGTGAGCTG„ 480,M₅₅1₅3„20,436,GGGGTGGTGAGCTGCAGCGA„

481 ,M55153„20,430,GTGAGCTGCAGCGAGAGGGT„ 482,M₅51₅3„20,424,TGCAGCGAGAGGGTGCAGTC„ 483,M₅51₅3„20,418,GAGAGGGTGCAGTCTTGCTG„ 484,M₅51₅3„20,412,GTGCAGTCTTGCTGGTCCAC„ 48₅,M55153„20,406,TCTTGCTGGTCCACCACGGT„

486,M55153„20,400,TGGTCCACCACGGTGGCTGT„ 487,M55153„20,394,ACCACGGTGGCTGTCCAGTC„ 488,M55153„20,388,GTGGCTGTCCAGTCACCCTC„ 489,M55153„20,382,GTCCAGTCACCCTCCTCCAC„ 490,M55153„20,376,TCACCCTCCTCCACAGCATC„

491_>M55153„20,370,TCCTCCACAGCATCTCTTAG„ 492,M55153„2₀,364,ACAGCATCTCTTAGTGGAAA„ 493,M55153„20,358,TCTCTTAGTGGAAAACGGGC„ 494,M55153„20,352,AGTGGAAAACGGGCCTTGGT„ 49₅,M₅5153„20,346,AAACGGGCCTTGGTCCCGGC„

496,M55153„2₀,340,GCCTTGGTCCCGGCCTCCTG„ 497,M55153„20,334,GTCCCGGCCTCCTGGCTAGG„ 498,M55153„20,328,GCCTCCTGGCTAGGGGCTGG„ 499,M55153„20,322,TGGCTAGGGGCTGGGCCGGT„ 500,M₅5153„20,316,GGGGCTGGGCCGGTCACGAC„ 501.M55153, ,20,310,GGGCCGGTCACGACACTGAA„

502,M551₅3_: ,20,304,GTCACGACACTGAAGGTGAG„

503,M₅₅1₅3„20,298,ACACTGAAGGTGAGACTGTC„ ₅04,M₅51₅3„20,292,AAGGTGAGACTGTCTACACT„ ₅05,M₅51₅3„20,286_;AGACTGTCTACACTGGCCTG„

506,M₅5153„20,280,TCTACACTGGCCTGGTAGTT„ 507,M55153„20,274,CTGGCCTGGTAGTTGCGGCC„ 508,M55153„20,268,TGGTAGTTGCGGCCCTCAAA„ 509,M55153„20,262,TTGCGGCCCTCAAAGTGCAG„ 510,M55153„20,256,CCCTCAAAGTGCAGGGTCAG„

511 ,M55153„20,250,AAGTGCAGGGTCAGCCAGAA„ 512,M55153„20,244,AGGGTCAGCCAGAAGGGCTG„ 513,M55153„20,238,AGCCAGAAGGGCTGGCCCCG„ 514,M55153„20,232,AAGGGCTGGCCCCGTCGCAC„ ₅1₅,M5₅1₅3„20,226,TGGCCCCGTCGCACCACCAG„

516,M5S153„20,220,CGTCGCACCACCAGCTTCTC„ 517,M₅₅1₅3„20,214,ACCACCAGCTTCTCCCGGCA„ ₅18,M₅₅1₅3„20,208,AGCTTCTCCCGGCACAGGTC„ 519,M₅5153„20,202,TCCCGGCACAGGTCGGCCGT„ 520,M₅51₅3„20,196,CACAGGTCGGCCGTGTGGTG„

521 ,M₅5153„20, 190,TCGGCCGTGTGGTGGTCTCG„ 522,M5₅153„20, 184,GTGTGGTGGTCTCGGCCATT„ 523,M55153„20,178,TGGTCTCGGCCATTGGTCTC„ 524,M55153„20,172,CGGCCATTGGTCTCCAGCTC„ 525_>M55153„20,166,TTGGTCTCCAGCTCCAGATC„

526,M55153„20, 160,TCCAGCTCCAGATCACACCT„ 527.M55153„20, 1₅4,TCCAGATCACACCTCTCTAA„ ₅28,M5₅1₅3„20,148,TCACACCTCTCTAAGACCAG„ ₅29,M₅5153„2₀₎142,CTCTCTAAGACCAGCTCCTC„ 530,M55153„20, 136,AAGACCAGCTCCTCGGCCAT„

531 ,M55153„20, 130,AGCTCCTCGGCCATGGTCGG„ 532,M55153„20,124,TCGGCCATGGTCGGGGCGGG„ 533.M55153„20, 118,ATGGTCGGGGCGGGGGCGGT„ 534.M55153„20,l 12,GGGGCGGGGGCGGTGGCTCC„ 535,M55153„20,106,GGGGCGGTGGCTCCTTCCAC„

536,M55153„20,100,GTGGCTCCTTCCACTGGCGG„ 537,M55153„20,94,CCTTCCACTGGCGGCCGAGA„ 538,M55153„20,88,ACTGGCGGCCGAGACCCTCC„ 539,M55153„20,82,GGCCGAGACCCTCCGTGAGA„ 540,M551₅3„20,76,GACCCTCCGTGAGATTTATG„

541,M55153„20,70,CCGTGAGATTTATGCTTTAA„ 542,M55153„20,64,GATTTATGCTTTAAGGAGGT„ 543, 55153„20,58,TGCTTTAAGGAGGTTCTATT„ 544,M55153„20,52,AAGGAGGTTCTATTTTGGTG„ 545,M55153„20,46,GTTCTATTTTGGTGTACTTT„

546,M55153„20,40,TTTTGGTGTACTTTGAAGTT„ 547,M55153„20,34,TGTACTTTGAAGTTTTGTTT„ ₅48,M55153„20,28,TTGAAGTTTTGTTTTGTTTC„ 549,M₅₅153„20_;22,TTTTGTTTTGTTTCAAGTTT„ ₅50,M₅5153„20_I16,TTTGTTTCAAGTTTAGAACT„

551,M55153„20,10,TCAAGTTTAGAACTGGCGTC„ 552,M55153„20,4,TTAGAACTGGCGTCACGCCT„ 553,BC002829„20,739,TTTTTTTTTTTTTTTTTTTT„ 554,BC002829„20,733,TTTTTTTTTTTTTTTTTTCA„ 555,BC002829„20,727,TTTTTTTTTTTTCAACAGAC„

556,BC002829„20,721,TTTTTTCAACAGACAAAAAA„ 557,BC002829„20,715,CAACAGACAAAAAAAGTTTA„ 558,BC002829„20,709,ACAAAAAAAGTTTATTGAAT„ ₅59,BC002829„20,703,AAAGTTTATTGAATACAAAA„ ₅60,BC002829„20,697,TATTGAATACAAAACTCAAA„

₅61 ,BC002829„20,691 ,ATACAAAACTCAAAGGCATC„ ₅62,BC002829„20,68₅,AACTCAAAGGCATCAACAGT„ ₅63,BC002829„20,679,AAGGCATCAACAGTCCTGGG„ 564,BC002829„20,673,TCAACAGTCCTGGGCCCAAA„ 565,BC002829„20,667,GTCCTGGGCCCAAAAGATCC„

566,BC002829„20,661,GGCCCAAAAGATCCATGGCA„ 567,BC002829„20,6₅₅,AAAGATCCATGGCAGGAAGT„ 568,BC002829„20,649,CCATGGCAGGAAGTCAAGAG„ 569,BC002829„20,643,CAGGAAGTCAAGAGTTCTGC„ 570,BC002829„20,637,GTCAAGAGTTCTGCTTCAGG„

571 ,BC002829„20,631 ,AGTTCTGCTTCAGGGTCGGT„ 572,BC002829„20,625,GCTTCAGGGTCGGTCTGGGC„ 573,BC002829„20,619,GGGTCGGTCTGGGCAGCCCT„ 574,BC002S29„20,613_JGTCTGGGCAGCCCTGGAAGA„ 575,BC002829„20,607,GCAGCCCTGGAAGAAGTCAT„ 576,BC002829„20,601 ,CTGGAAGAAGTCATTGCACA„

577,BC002829„20,595,GAAGTCATTGCACATGACAG„

578,BC002829„20,589,ATTGCACATGACAGTGATGA„

579,BC002829„20,583,CATGACAGTGATGAGTGCCA„ 580,BC002829„20,577,AGTGATGAGTGCCAGGAAAA„

581 ,BC002829„20,571 ,GAGTGCCAGGAAAACAGCAT„

582,BC002829„20,565,CAGGAAAACAGCATACTCCT„

583,BC002829„20,559,AACAGCATACTCCTGGAAGT„

584,BC002829„20,553,ATACTCCTGGAAGTCCACCT„ 585,BC002829„20,547,CTGGAAGTCCACCTGCTGGT„

586,BC002829„20,541,GTCCACCTGCTGGTCACTGT„

587,BC002829„20,53₅,CTGCTGGTCACTGTTCTCAT„

588,BC002829„20,529,GTCACTGTTCTCATCCAGGC„

589,BC002829„20,523,GTTCTCATCCAGGCTGCCCA„ 590,BC002829„20,517,ATCCAGGCTGCCCATCAGCT„

591,BC002829„20₎511,GCTGCCCATCAGCTTCTTCA„

592,BC002829„2₀,505_JCATCAGCTTCTTCAGCCCCT„

593,BC002829„20,499,CTTCTTCAGCCCCTCCTCAT„

594,BC002829„20,493,CAGCCCCTCCTCATCCACTT„ 59₅,BC002829„20,487,CTCCTCATCCACTTTCTCCC„

596,BC002829„20,481 ,ATCCACTTTCTCCCCCACAA„

597,BC002829„20,475,TTTCTCCCCCACAAAGCTGG„

598,BC002829„20,469,CCCCACAAAGCTGGGCAGCT„

599,BC002829„20,463,AAAGCTGGGCAGCTCCTTGT„ 600,BC002829„20,457,GGGCAGCTCCTTGTGCAGAA„

601 ,BC002829„20,451 ,CTCCTTGTGCAGAAGTTCCT„

602,BC002829„20,44S,GTGCAGAAGTTCCTTCATTT„

603,BC002829„20,439,AAGTTCCTTCATTTCCCCCT„

604,BC002829„20,433,CTTCATTTCCCCCTTACTCA„ 605,BC002829„20,427,TTCCCCCTTACTCAGCTTGA„

606,BC002829„20,421 ,CTTACTCAGCTTGAACTTGT„

607,BC002829„20,415,CAGCTTGAACTTGTCGCCCT„

608,BC002829„20,409,GAACTTGTCGCCCTCTTGGC„

609,BC002829„20,403,GTCGCCCTCTTGGCAGGAGT„ 610,BC002829„20,397,CTCTTGGCAGGAGTACTTGT„

611 ,BC002829„20,391 ,GCAGGAGTACTTGTGGAAGG„

612,BC002829„20,385,GTACTTGTGGAAGGTAGTGA„

613,BC002829„20,379,GTGGAAGGTAGTGACCAGCA„

614,BC002829„20,373,GGTAGTGACCAGCACAGCCA„ 615,BC002829„20,367,GACCAGCACAGCCAGCGCCT„

616,BC002829„20_;361 ,CACAGCCAGCGCCTGCTCCA„

617,BC002829„20,3₅₅,CAGCGCCTGCTCCAGAGAAC„

618,BC002829„20,349,CTGCTCCAGAGAACTGCACA„

619,BC002829„20,343,CAGAGAACTGCACATCATGG„ 620,BC002829„20,337,ACTGCACATCATGGATCTGT„

621 ,BC002829„20,331 ,CATCATGGATCTGTGGCAGA„

622,BC002829„20,325,GGATCTGTGGCAGACCAGGT„

623 ,BC002829„20,319,GTGGCAGACCAGGTGGCAGA„

624,BC002829„20,313 ,GACCAGGTGGCAGAGACAGA„ 62₅,BC002829„20,307,GTGGCAGAGACAGACCCAGG„

626,BC002829„20,301 ,GAGACAGACCCAGGAAGGAG„

627,BC002829„20,295,GACCCAGGAAGGAGAGCAAG„

628,BC002829„20,289,GGAAGGAGAGCAAGGCAGCC„

629,BC002829„20,283,AGAGCAAGGCAGCCAGGCTC„ 630,BC002829„20,277,AGGCAGCCAGGCTCCCAGGG„

631 ,BC002829„20,271 ,CCAGGCTCCCAGGGTGAGGA„

632,BC002829„20,265,TCCCAGGGTGAGGATTTATA„

633,BC002829„20,2₅9,GGTGAGGATTTATATGTGGG„

634,BC002829„20,2₅3,GATTTATATGTGGGCCCCAC„ 63₅,BC002829„20,247,TATGTGGGCCCCACTGGCCC„

636,BC002829„20,241,GGCCCCACTGGCCCCCAACT„

637,BC002829,,20,23₅,ACTGGCCCCCAACTTGGCAT„

638,BC002S29„20,229,CCCCAACTTGGCATTTTAAG„

639,BC002829„20,223,CTTGGCATTTTAAGGAAACC„ 640,BC002829„20,217,ATTTTAAGGAAACCAAACCT„

641 ,BC002829„20,211 ,AGGAAACCAAACCTGCCTCA„

642,BC002829„20,205,CCAAACCTGCCTCAACCTGA„

643,BC002829„20,199,CTGCCTCAACCTGATCCCAC„

644,BC002829„20,193,CAACCTGATCCCACCAAACC„ 64₅₎BC002829„20,187,GATCCCACCAAACCCTGGCC„

646,BC002829„20, 181 ,ACCAAACCCTGGCCTCTTGC„

647,BC002829„20_J17₅,CCCTGGCCTCTTGCCATTCC„

648,BC002829„20, 169.CCTCTTGCCATTCCCACTCA,,

649,BC002829,,20,163,GCCATTCCCACTCATTCCCT,, 650,BC002829„20,157,CCCACTCATTCCCTCCCAGC„ 651 ,BC002829„20, 151 ,CATTCCCTCCCAGCCCCCTC„

652,BC002829„20,145,CTCCCAGCCCCCTCCCTCCC„

653,BC002829„20,139,GCCCCCTCCCTCCCAGAGAG„

654,BC002829„20,133,TCCCTCCCAGAGAGTGCCAG„ 655,BC002829„20, 127,CCAGAGAGTGCCAGCTCCAC„

656,BC002829„20,121,AGTGCCAGCTCCACCACCAG„

657,BC002829„20, 115,AGCTCCACCACCAGCTGGGG„

658,BC002829„20, 109,ACCACCAGCTGGGGGAGGGC„

659,BC002829„20,103,AGCTGGGGGAGGGCTCTAGG„ 660,BC002829„2₀,97,GGGAGGGCTCTAGGCCAGGT„

661 ,BC002829„20,91 ,GCTCTAGGCCAGGTCAAGGG„

662,BC002829„20,85,GGCCAGGTCAAGGGCAGCCC„

663,BC₀02829„20,79,GTCAAGGGCAGCCCCTGAGC„

664,BC002829„20,73,GGCAGCCCCTGAGCCCACCC„ 665,BC002829„20,67,CCCTGAGCCCACCCAGGCCA„

666,BC002829„20,61,GCCCACCCAGGCCACAGTGG„

667,BC002829„20,55,CCAOGCCACAGTGGGAAGTG„

668,BC002829„20,49,CACAGTGGGAAGTGGGAGGT„

669,BC002829„20,43,GGGAAGTGGGAGGTGTCGTG„ 670,BC002829„20,37,TGGGAGGTGTCGTGGGGACT„

671 ,BC002829„20,31 ,GTGTCGTGGGGACTGGGCAT„

672,BC002829„20,25,TGGGGACTGGGCATCCTGGA„

673,BC002829„20, 19,CTGGGCATCCTGGACCGGGG„

674,BC002829„20,13,ATCCTGGACCGGGGTGAGGG„ 675,BC002829„20,7,GACCGGGGTGAGGGGAGCCT„

676,BC002829„20, 1 ,GGTGAGGGGAGCCTCGTGCC„

677,NM_003155„20,3882,TTTTTTTTTTTTTTTTTTTT„

678,NM_003155„20,3876,TTTTTTTTTTTTTTGAAACC„

679,NM_003155„20,3870 TTTTTTTGAAACCAATAAA,, 680,NM_00315₅„20,3864,TTGAAACCAATAAAACGTAA„

681_JNM_003155„20,3858,CCAATAAAACGTAACACTTT„

682,NM_003155„20,3852,AAACGTAACACTTTATTATT„

683,NM_003155„20,3846,AACACTTTATTATTATTTTT„

684,NM_003155„20,3840,TTATTATTATTTTTATCTTA„ 685.NM 003155„20,3834,TTATTTTTATCTTAGAAGGA„

686,NM )03155„20,3828,TTATCTTAGAAGGAATTCAC„

687,NM_003155„20,3822,TAGAAGGAATTCACCAAAGG„

688,NM )031SS,,20,3816,GAATTCACCAAAGGCTTCAT,,

689,NM_003155„20,3810,ACCAAAGGCTTCATATTATG„ 690,NM_003155„20,3804,GGCTTCATATTATGCTATGG„

691 ,NM_003155„20,3798,ATATTATGCTATGGCATCTT„

692,NM_0031₅₅„20,3792,TGCTATGGCATCTTTAATTA„

693,NM_0031₅₅„20,3786,GGCATCTTTAATTATAAAAA„

694,NM_0031₅₅„20,3780,TTTAATTATAAAAAATAAGC„ 695,NM_003155„20,3774,TATAAAAAATAAGCAAATAA„

696,NM_003155„20,3768,AAATAAGCAAATAAAATAAC„

697,NM_003155„20,3762,GCAAATAAAATAACTTGCAT„

698,NMJ)03155„20,3756,AAAATAACTTGCATCTGTCA,,

699,NM_003155„20,3750,ACTTGCATCTGTCATTACCA„ 700,NM_003155„20,3744,ATCTGTCATTACCATGATAT„

701 ,NM_00315₅„20,3738,CATTACCATGATATGTTTCA„

702,NM_003155„20,3732,CATGATATGTTTCATAACCT„

703,NM_0031₅₅„20,3726,ATGTTTCATAACCTTTATAT„

704,N _003155„20,3720,CATAACCTTTATATGCACAT„ 705,NM_003155„20,3714,CTTTATATGCACATGGAGCT„^"

706,NM_003155„20,3708,ATGCACATGGAGCTTAAAAA„

707,NM_003155„20,3702,ATGGAGCTTAAAAAATGTAA„

708₎NM_003155„20,3696,CTTAAAAAATGTAATTTAAC„

709,NM_003155„20,3690,AAATGTAATTTAACAATAAA„ 710,NM_003155„20,3684,AATTTAACAATAAATAATGA„

711,NM_003155„20,3678,ACAATAAATAATGACATATA„

712,NM_003155„20,3672,AATAATGACATATACCAGAT„

713,NM_003155„20,3666,GACATATACCAGATATGCTC„

714,NM_003155„20,3660,TACCAGATATGCTCACTGTT„ 715.NM 0031₅₅„20,3654,ATATGCTCACTGTTTATTCC„

716,NM~ 0031₅₅„20,3648,TCACTGTTTATTCCAGTACT„

717,NM )031₅5„20,3642,TTTATTCCAGTACTCAGCCA„

718,NM_003155„20,3636,CCAGTACTCAGCCAAAAACC„

719,NM_003155„20,3630,CTCAGCCAAAAACCTAAATA„ 720,NM_003155„20,3624,CAAAAACCTAAATATCATTT„

721 ,NM_003155„20,3618,CCTAAATATCATTTAAATTA„

722,NM )03155„20,3612,TATCATT AAATTATAAATA„

723,NM_0031₅5„20,3606,TTAAATTATAAATACATAAT„

724,NM_0031₅5„20,3600,TATAAATACATAATGCAAAT„ 725,NM )03155„20,3594,TACATAATGCAAATATAATG„ 726,NMJ)03155,,20,3588,ATGCAAATATAATGGCACAA„

727,NM_003155„20,3582,ATATAATGGCACAAAAATGT„

728,NM_003155„20,3576,TGGCACAAAAATGTCTAAAG„

729,NM_003155„20,3570,AAAAATGTCTAAAGTGCAAC„ 730,NM_003155„20,3564,GTCTAAAGTGCAACCAAATC„

731,NM_003155„20,3558,AGTGCAACCAAATCACAAGA„

732,NM_003155„20,3552,ACCAAATCACAAGAGAAGAA„

733,NM_0031₅₅„20,3₅46,TCACAAGAGAAGAATCATGC„

734,NM_0031₅₅„20,3₅40,GAGAAGAATCATGCAAACTG„ 735,NM_003155„20,3534,AATCATGCAAACTGGTCTAG„

736,NM_003155„20,3528₎GCAAACTGGTCTAGGTCAGC„

737,NM_003155„20,3522,TGGTCTAGGTCAGCCCCCGA„

738,NM_003155„20,3516,AGGTCAGCCCCCGAATCACT„

739,NM_003155„20,3510,GCCCCCGAATCACTCTGCAG„ 74₀,NM )03155,,20,3504,GAATCACTCTGCAGCAAACA,,

741,NM_003155„20,3498,CTCTGCAGCAAACACAAGAC„

742,NM_003155„20,3492,AOCAAACACAAGACGAAGCT„

743,NM_003155„20,3486,CACAAGACGAAGCTTTGGAA„

744,NM_003155„20,34S0,ACGAAGCTTTGGAAGTTTAA„ 745,NM_003155„20,3474,CTTTGGAAGTTTAAGGGGGG„

746,NM_003155„20,3468,AAGTTTAAGGGGGGAATTGG„

747,NM_003155„20,3462,AAGGGGGGAATTGGAGGGAG„

748,NM_003155„20,3456,GGAATTGGAGGGAGTAGGGT„

749,NM_0031₅₅„20,3450,GGAGGGAGTAGGGTGGGGGA„ 750,NM_003155„20,3444,AGTAGGGTGGGGGAAAGAGA„

7₅1 ,NM_0031₅₅„20,3438,GTGGGGGAAAGAGAAGCAAA„

7₅2,NM_003155„20,3432,GAAAGAGAAGCAAAAAACTA„

753,NM_0₀3155„20,3426,GAAGCAAAAAACTAGCAACA„

754,NM_003155„20,3420,AAAAACTAGCAACATGTGAG„ 755,NM_003155,,20,3414,TAGCAACATGTGAGAACTGC„

756,NM_003155„20,3408_JCATGTGAGAACTGCTTCTTT„

757,NM_0031₅₅„20,3402,AGAACTGCTTCTTTCTGTAT„

7₅8,NM_0031₅₅„20,3396,GCTTCTTTCTGTATGTGTAG„

7S9,NM_003155„20,3390,TTCTGTATGTGTAGATATAT„ 760,NM_003155„20,3384,ATGTGTAGATATATGTATTG„

761,NM_003155„20,3378,AGATATATGTATTGTAGATA„

762,NM_00315₅„20,3372,ATGTATTGTAGATACATATA„

763,NM_0031₅5„20,3366,TGTAGATACATATATAGATA„

764,NM_00315₅„20_>3360,TACATATATAGATATCATCG„ 76₅,NM_0031₅₅„20,3354,TATAGATATCATCGTGGGGA„

766,NM_003155„20,3348,TATCATCGTGGGGAGAAAAG„

767,NM_003155„20,3342,CGTGGGGAGAAAAGGGGGGG„

768,NM_00315₅„20,3336,GAGAAAAGGGGGGGTACCAC„

769,NM_00315₅„20,3330,AGGGGGGGTACCACGGTTTG„ 770,NM_00315₅„20,3324,GGTACCACGGTTTGAAGAGG„

771 ,NM_003155„20,3318,ACGGTTTGAAGAGGTCACAG„

772,NM_00315₅„20,3312,TGAAGAGGTCACAGCCAAAA„

773,NM_00315₅,,20,3306,GGTCACAGCCAAAAAAAAAA„

774,NM_003155„20,3300,AGCCAAAAAAAAAAAAAAAA„ 775,NM_003155„20,3294,AAAAAAAAAAAAAAAAAAAA„

776,NM_003155„20,3288,AAAAAAAAAAAAAAGAAAAG„

777,NM_003155„20,3282,AAAAAAAAGAAAAGAAAAAA„

778,NM_003155„20,3276,AAGAAAAGAAAAAAGGAAAT„

779,NM_0031₅₅„20,3270,AGAAAAAAGGAAATCTACTG„ 780,NM_0031₅₅„20,3264,AAGGAAATCTACTGAACTGA„

781,NM_0031₅₅„20,32₅8,ATCTACTGAACTGAAGAAAG„

782,NM_0031₅₅„20,32₅2,TGAACTGAAGAAAGAGAGAA„

783,NM_00315₅„20,3246,GAAGAAAGAGAGAAATTTGC„

784,NM_003155„20,3240,AGAGAGAAATTTGCTAGGAA„ 785,NM_003155„20,3234,AAATTTGCTAGGAATACTCA„

786,NM_003155„20,3228,GCTAGGAATACTCATGAACT„

787,NM_003155„20,3222,AATACTCATGAACTACTTGT„

788,NMJ)03155„20,3216,CATGAACTACTTGTCGCATT„

789,NM_0031₅₅„20,3210,CTACTTGTCGCATTGGGGTC„ 790,NM_0031₅₅„20,3204,GTCGCATTGGGGTCCTGGCT„

791 ,NM_003155„20,3198,TTGGGGTCCTGGCTTAGTTG„

792,NM_003155„20,3192,TCCTGGCTTAGTTGGGTTTG„

793_>NM_003155„20,3186,CTTAGTTGGGTTTGCAAAAT„

794,NM_003155„20,3180,TGGGTTTGCAAAATGGACAC„ 795,NM_003155„20,3174,TGCAAAATGGACACAACACA„

796,NM_003155„20,3168,ATGGACACAACACACAAACT„

797,NM 003155„20,3162,ACAACACACAAACTTTAATA„

798,NM θ03155„20,3156,CACAAACTTTAATAGCTTTT„

799,NM_003155„20,3150,CTTTAATAGCTTTTCTGATT„ 800,NM_003155„20,3144,TAGCTTTTCTGATTCAGAGA„ 801 ,NM_003155„20,3138,TTCTGATTCAGAGAAGTCAG„

802,NM_003155„20,3132,TTCAGAGAAGTCAGCCTTGC„

803,NM_00315₅„20,3126,GAAGTCAGCCTTGCCTGGGG„

804,NM_003155„20,3120,AGCCTTGCCTGGGGGTGGGA„ 805,NM_0031₅₅„20,3114,GCCTGGGGGTGGGAAGTGTG„

806,NM_0031₅₅„20,3108,GGGTGGGAAGTGTGGGAGGG„

807,NM_0031₅₅„20,3102,GAAGTGTGGGAGGGAGGGGA„

808,NM_0031₅₅„20,3096,TGGGAGGGAGGGGAAGAGTC„

809,NM_003155„20,3090,GGAGGGGAAGAGTCTAACTT„ 810,NM_0031₅₅,,20,3084,GAAGAGTCTAACTTAGAATA„

811,NM_003155„20,3078,TCTAACTTAGAATATGGTCT„

812,NM_003155„20,3072,TTAGAATATGGTCTACCTGA„

813,NM_003155„20,3066,TATGGTCTACCTGATTTCCA„

814,NM_0031₅₅„20,3060,CTACCTGATTTCCAAGAGGC„ 815,NM_003155„20,3054,GATTTCCAAGAGGCTAAGGC„

816,NM_003155„20,3048,CAAGAGGCTAAGGCAGTGTC„

817,NM_003155„20,3042,GCTAAGGCAGTGTCCATAAG„

818,NM_0031₅₅„20,3036,GCAGTGTCCATAAGTTTGGG„

819,NM 0031₅₅„20,3030,TCCATAAGTTTGGGGACCTG„ 820,NM~ 003155„20,3024,AGTTTGGGGACCTGGGGATG„

821 ,NM_003155„20,3018,GGGACCTGGGGATGGGACAG„

822,NM_003155„20,3012,TGGGGATGGGACAGTTCTGA„

823,NM_003155„20,3006,TGGGACAGTTCTGAGTATAA„

824,NM_003155„20,3000,AGTTCTGAGTATAAAAATGC„ 825,NM_003155„20,2994,GAGTATAAAAATGCCCTTAA„

826,NM_003155„20,2988,AAAAATGCCCTTAACAATCT„

827,NM_003155„20,2982,GCCCTTAACAATCTGATGTC„

828,NM_003155„20,2976,AACAATCTGATGTCAGCACG„

829,NM_003155„20,2970,CTGATGTCAGCACGCTTAGA„ 830,NM_003155„20,2964,TCAGCACGCTTAGAGGCTGT„

831 ,NM_003155„20,2958,CGCTTAGAGGCTGTGTGGGG„

832,NM_003155„20,2952,GAGGCTGTGTGGGGACAAAG„

833,NM_003155„20,2946,GTGTGGGGACAAAGGCAGCA„

834,NM_003155„20,2940,GGACAAAGGCAGCAATGTTT„ 835,NM_003155„20,2934,AGGCAGCAATGTTTGTGCTG„

836,NM_0031₅₅„20,2928,CAATGTTTGTGCTGCTGCTG„

837,NM_0031₅₅„20,2922,TTGTGCTGCTGCTGCTGCTG„

838,NM_003155„20,2916,TGCTGCTGCTGCTGCTGGGT„

839,NM_0031₅₅„20,2910,TGCTGCTGCTGGGTCTGCTG„ 840,NM_003155„20,2904,TGCTGGGTCTGCTGCAATTG„

841 ,NM_003155„20,2898,GTCTGCTGCAATTGCTCTTG„

842,NM_003155„20,2892,TGCAATTGCTCTTGGTCCTT„

843,NM_003155„20,2886,TGCTCTTGGTCCTTGAGCAG„

844,NM_003155„20,2880,TGGTCCTTGAGCAGCACGTT„ 845,NM_0031₅₅„20,2874,TTGAGCAGCACGTTACTGGT„ ,

846,NM_003155„20,2868,AGCACGTTACTGGTTTTAAA„

847,NM_003155,,20,2862,TTACTGGTTTTAAAGGCTTT„

848,NM_003155,,20,2856,GTTTTAAAGGCTTTATGGTA„

849_INM_003155„20,2850,AAGGCTTTATGGTAAAGTTG„ 850,NM_003155„20,2844,TTATGGTAAAGTTGTATTGC„

851 ,NM_003155„20,2838,TAAAGTTGTATTGCTTTTCA„

852,NM_003155„20,2832,TGTATTGCTTTTCATTTTTC„

853,NM_003155„20,2826,GCTTTTCATTTTTCTGGAGA„

854,NM_003155„20,2820,CATTTTTCTGGAGATGTGCC„ 855,NM_003155„20,2814,TCTGGAGATGTGCCCTCTCT„

856,NM_003155„20,2808,GATGTGCCCTCTCTCCTCCC„

857,NM_0031₅₅„20,2802,CCCTCTCTCCTCCCACCAGG„

8₅8,NM_0031₅₅„20,2796,CTCCTCCCACCAGGATCCCT„

8₅9,NM_003155„20,2790,CCACCAGGATCCCTATCACT„ 860,NM_003155„20,2784,GGATCCCTATCACTCGATTT„

861 ,NM_003155„20,2778,CTATCACTCGATTTGGTCAA„

862,NM_003155„20,2772,CTCGATTTGGTCAAATCTTG„

863,NM_003155„20,2766,TTGGTCAAATCTTGAGTTTA„

864,NM_003155„20,2760,AAATCTTGAGTTTAGCCTAG„ 865,NM_003155„20,2754,TGAGTTTAGCCTAGTGAGAG„

866,NM_003155„20,2748,TAGCCTAGTGAGAGTCGAGC„

S67,NM_00315₅„20,2742,AGTGAGAGTCGAGCACCAAT„

868_JNM_003155„20,2736,AGTCGAGCACCAATAGTTTC„

869_>NM_003155„20_;2730,GCACCAATAGTTTCTACCTA„ 870,NM_003155„20,2724,ATAGTTTCTACCTAAGCGAG„

871 ,NM_0031-55„20,2718,TCTACCTAAGCGAGTTTGGA„

872,NM_003155„20,2712,TAAGCGAGTTTGGAGTGGCC„

873,NM 003155„20,2706,AGTTTGGAGTGGCCCCTGCA„

874,NM 003155„20,2700,GAGTGGCCCCTGCAGTCCTA„ 875,NM_003155„20,2694,CCCCTGCAGTCCTACCCCTC„

951 ,NM_003155„20,2238,AGTACCAGGCACCGATGAAA„

952,NM_003155„20,2232,AGGCACCGATGAAAGGGGAC„

953,NM_003155„20,2226,CGATGAAAGGGGACGAGTAA„

954,NM_003155„20,2220,AAGGGGACGAGTAAAGAACT„ 955,NMJ)03155,,20,2214,ACGAGTAAAGAACTACCACT„

956,NM_003155,,20,2208,AAAGAACTACCACTTCCTAA„

957,NM_003155„20,2202,CTACCACTTCCTAATGTATA„

958,NM_003155„20,2196,CTTCCTAATGTATAGTAGGC„

959.NM 003155„20,2190.AATGTATAGTAGGCCTTATC,, 960.NM J)03155„20,2184,TAGTAGGCCTTATCACACTG„

961 ,NM_003155„20,2178,GCCTTATCACACTGTAAGTG„

962,NM_003155„20,2172,TCACACTGTAAGTGGTCCAA„

963,NM_003155„20,2166,TGTAAGTGGTCCAAGCCCAT„

964,NM_003155„20,2160,TGGTCCAAGCCCATAGGGAT„ 965,NM_003155„20,2154,AAGCCCATAGGGATGCTCTT„

966,NM_003155„20,2148,ATAGGGATGCTCTTTTTGGT„

967,NM_003155„20,2142,ATGCTCTTTTTGGTTCCTGG„

968,NM_003155„20,2136,TTTTTGGTTCCTGGAATTTC„

969,NM_003155„20,2130,GTTCCTGGAATTTCCAGTTG„ 970,NM_003155„20,2124,GGAATTTCCAGTTGGATGTG„

971 ,NM_003155„20,2118.TCCAGTTGGATGTGACAGAG,,

972,NM_003155„20,2112,TGGATGTGACAGAGATCTTT„

973,NM_0031₅5„20,2106,TGACAGAGATCTTTCAGTAT„

974,NM_003155„20,2100,AGATCTTTCAGTATAGGTCT„ 975,NM_003155,,20,2094,TTCAGTATAGGTCTAAGTCA„

976,NM_003155„20,2088,ATAGGTCTAAGTCAAGAGTA„

977,NM_003155„20,2082,CTAAGTCAAGAGTAGCCTCT„

978,NM_003155„20,2076,CAAGAGTAGCCTCTGGGTTG„

979,NM_00315₅„20,2070,TAGCCTCTGGGTTGAGGTGG„ 980.NM 003155„20,2064,CTGGGTTGAGGTGGGCTGGG„

981,NMJ)03155„20,2058,TGAGGTGGGCTGGGAGATTA„

982,NM_003155„20,2052,GGGCTGGGAGATTAACATCT„

983,NM_003155„20,2046,GGAGATTAACATCTTACCTG„

984,NM_003155„20,2040,TAACATCTTACCTGGGGTCC„ 985,NM_003155„20,2034,CTTACCTGGGGTCCTTCAGA„

986,NM_003155„20,2028,TGGGGTCCTTCAGATAAACC„

987,NM_003155„20,2022,CCTTCAGATAAACCTGTTGG„

988,NM_003155„20,2016,GATAAACCTGTTGGTTTTTC„

989,NM_003155„20,2010,CCTGTTGGTTTTTCCTGTCT„ 990,NM_003155„20,2004,GGTTTTTCCTGTCTCATACA„

991 ,NM_003155„20, 1998,TCCTGTCTCATACAGGCCCA„

992,NM_003155„20, 1992,CTCATACAGGCCCATCTTAA„

993,NM_003155„20,1986,CAGGCCCATCTTAAGTTTTG„

994,NMJ)03155,,20,1980,CATCTTAAGTTTTGATGTTG„ 995,NM_003155„20, 1974,AAGTTTTGATGTTGAATTAA„

996,NM_003155„20, 1968,TGATGTTGAATTAAAACTAC„

997,NM_003155„20,1962,TGAATTAAAACTACTTCTAC„ ^" "

998,NM_003155„20, 1956,AAAACTACTTCTACCCCCTT„

999,NM_003155„20, 1950,ACTTCTACCCCCTTAGTTAT„ 1000.NM 003155„20,1944,ACCCCCTTAGTTATAAAAAA„

1001,NM θ03155„20,1938,TTAG TATAAAAAAGGCCAC„

1002,NM_003155„20, 1 32,ATAAAAAAGGCCACAAGGAG„

1003,NM_003155..20, 1926,AAGGCCACAAGGAGCATTTA„

1004,NM 003155„20, 1920.ACAAGGAGCATTTATGTGGA,, 1005,NM )03155..20, 1914,AGCATTTATGTGGATATCTG„

1006,NM_003155„20, 1908,TATGTGGATATCTGGAAGTG„

1007,NM_003155„20, 1902,GATATCTGGAAGTGAGATAG„

1008,NM_003155„20, 1896,TGGAAGTGAGATAGTTATTC„

1009,NM_003155„20, 1890,TGAGATAGTTATTCCATTCC„ 1010_>NM_003155„20,1884,AGTTATTCCATTCCCAGGAA„

1011 ,NM_003155„20, 1878,TCCATTCCCAGGAAAAGAAA„

1012,NM_003155„20,1872,CCCAGGAAAAGAAAAATAAA„

1013,NM_003155„20,1866,AAAAGAAAAATAAAGCTAAG„

1014,NM_003155..20, 1860,AAAATAAAGCTAAGTTACAA„ 1015,NM_003155„20, 1854,AAGCTAAGTTACAAAACTAA„

1016,NM_003155„20, 1848,AGTTACAAAACTAAATCTAT„

1017,NM_003155„20, 1842,AAAACTAAATCTATATGCAA„

1018,NM_003155„20, 1836,AAATCTATATGCAATAAAGT„

1019,NM_003155„20,1830,ATATGCAATAAAGTTATTAT„ 1020,NM_003155..20, 1824,AATAAAGTTATTATATACTG„

1021,NM_003155„20, 1818,GTTATTATATACTGCTTTGT„

1022.NM 0031₅5„20, 1812,ATATACTGCTTTGTTTAAGC„

1023,NM3031₅5„20,1806,TGCTTTGTTTAAGCAGAGTC„

1024,NM_003155..20, 1800,GTTTAAGCAGAGTCCTCTGG„ 1025,NM_003155„20,1794,GCAGAGTCCTCTGGAATTTA„ 1026,NM_0031₅₅„20,1788,TCCTCTGGAATTTATGTACA„ 1027,NM_0031₅₅„20, 1782,GGAATTTATGTACAGTACAT„ 1028.NM J)031_55>,20, 1776,TATGTACAGTACATTAGTTT„ 1029,NM_003155„20, 1770,CAGTACATTAGTTTTCAGCT„ 1030,NM_003155„20, 1764,ATTAGTTTTCAGCTATTTAT„

1031 ,NM_003155„20, 1758,TTTCAGCTATTTATATTCCA„ 1032,NM_003155„20, 1752,CTATTTATATTCCACAGTTA„ 1033,NM_003155„20,1746,ATATTCCACAGTTAGACCTT„ 1034,NM_003155„20, 1740,CACAGTTAGACCTTAAGATT„ 1035,N _003155„20,1734,TAGACCTTAAGATTCTCTGG„

1036,NM_0031₅₅„20,1728,TTAAGATTCTCTGGTTTTAA„ 1037,NM_003155„20,1722 TCTCTGGTTTTAAGACAAT,, 1038,NM_003155„20, 1716,GGTTTTAAGACAATTGTTAA„ 1039,N _003155„20, 1710,AAGACAATTGTTAAAGATAC„ 1040,NM_003155„20, 1704,ATTGTTAAAGATACTTTTAA„

1041 ,NM_003155„20, 1698,AAAGATACTTTTAAAGCTCT„ 1042,NM_003155„20, 1692,ACTTTTAAAGCTCTGAGCAG„ 1043,N _003155„20,1686,AAAGCTCTGAGCAGTTACAG₎, 1044,N _003155„20, 1680,CTGAGCAGTTACAGTACGTA„ 1045,NM_003155„20, 1674,AGTTACAGTACGTAAAGATG„

1046,NM_003155„20, 1668,AGTACGTAAAGATGTTAGCT„ 1047,NM_0031₅₅„20, 1662.TAAAGATGTTAGCTTTTTGT,, 1048,NM_00315₅„20, 16₅6,TGTTAGCTTTTTGTTTTTCA„ 1049,NM_003155„20,1650,CTTTTTGTTTTTCATTAGAT„ 1050,NM_003155„20, 1644,GTTTTTCATTAGATGCAAGA„

1051 ,NM_003155„20, 1638,CATTAGATGCAAGAAGATGC„ 1052,NM_003155„20,1632,ATGCAAGAAGATGCAGGCTC„ 1053,NM_003155„20, 1626,GAAGATGCAGGCTCAAAGTC„ 1054,NM_003155„20, 1620,GCAGGCTCAAAGTCTGGTTG„ 1055,N _003155„20, 1614,TCAAAGTCTGGTTGGACAGC„

1056,NM_003155„20,1608,TCTGGTTGGACAGCCAGGCT„ 1057,NM_0031₅5„20,1602,TGGACAGCCAGGCTCAAGCA„ 1058,NM_003155„20,1596,GCCAGGCTCAAGCAATTTGG„ 1059,NM_003155„20, 1590,CTCAAGCAATTTGGTAAATG„ 1060,NM_003155„20, 1584,CAATTTGGTAAATGTGTCGG„

1061,NM_003155„20, 1578,GGTAAATGTGTCGGAAAGAA„ 1062,NM_003155„20, 1572,TGTGTCGGAAAGAAAATTAG„ 1063,NM_003155„20,1566,GGAAAGAAAATTAGACATTG„ 1.064,NM_003155„20, 1560,AAAATTAGACATTGGAGGAT„ 1065,NM_003155„20, 1554,AGACATTGGAGGATCAAGAC„

1066,NM_003155„20, 1548.TGGAGGATCAAGACCATAAG,, 1067,NM_003155„20, 1542,ATCAAGACCATAAGACACTA„ 1068,N _0031₅₅„20,1536,ACCATAAGACACTAGCTCAT„ 1069,NM_0031₅₅„20J₅30,AGACACTAGCTCATTAGAGA„ 1070,NM_003155„20, 1524,TAGCTCATTAGAGATCAAGA„

1071 ,NM_003155„20, 1₅18,ATTAGAGATCAAGAATTCAA„ 1072,NM_003155„20, 1512,GATCAAGAATTCAAATGTGA„ 1073,NM_003155„20, 1506,GAATTCAAATGTGACATTCA„ 1074,NM_003155„20, 1500,AAATGTGACATTCATATTCG„ 1075,NM_003155„20,1494,GACATTCATATTCGTCCATG„

1076,NM_003155„20,1488,CATATTCGTCCATGGCCAGC„ 1077,NM_003155„20_;1482,CGTCCATGGCCAGCACAGAT„ 1078,NM_003155„20, 1476,TGGCCAGCACAGATTCATAA„ 1079,NM_003155„20, 1470,GCACAGATTCATAACACGAA„ 1080,NM_003155„20, 1464,ATTCATAACACGAATTCCAT„

1081 ,NM_003155„20, 1458,AACACGAATTCCATTTAACA„ 1082,NM_003155„20,1452,AATTCCATTTAACATCTTTA„ 1083,NM_003155„20, 1446,ATTTAACATCTTTATGAGCA„ 1084,NM_003155„20, 1440,CATCTTTATGAGCATTTAAG„ 1085,NM_003155„20,1434,TATGAGCATTTAAGACATGC„

1086,NM_003155„20,1428,CATTTAAGACATGCATTTAA„ 1087,NM_003155„20,1422,AGACATGCATTTAAATAAAG„ 10S8,NM )03155,,20,1416,GCATTTAAATAAAGTTTCCT„ 1089,NM_003155„20, 1410.AAATAAAGTTTCCTTATCAG,, 1090,NM_003155„20,1404,AGTTTCCTTATCAGCTAACT„

1091,NM )03155,,20,1398,CTTATCAGCTAACTCTACTG„ 1092,NM_003155„20,1392,AGCTAACTCTACTGGGGCAA„ 1093,N _003155„20, 1386,CTCTACTGGGGCAACCGTTC„ 1094,NM_003155„20,1380,TGGGGCAACCGTTCTAAAGG„ 1095,N _003155„20, 1374,AACCGTTCTAAAGGGATCCA„

1096,NM_003155„20,1368,TCTAAAGGGATCCACATCTT„ 1097,NM_003155„20,1362,GGGATCCACATCTTCAAATT„ 1098,NM_003155„20,1356,CACATCTTCAAATTACAATG„ 1099,N _0031₅₅„20,1350,TTCAAATTACAATGGCTGGA„ 1100,N _003155„20,1344,TTACAATGGCTGGAGAGTTA„ 1101.NM 003155 ,20, 1338,TGGCTGGAGAGTTACATGAA„ 1102.NM 003155 ,20, 1332,GAGAGTTACATGAATGTTTT„ 1103.NM 003155 ,20, 1326,TACATGAATGTTTTGTGTTT„ 1104.NM 003155 ,20, 1320,AATGTTTTGTGTTTGGGGGT„ 1105.NM 003155 ,20, 1314,TTGTGTTTGGGGGTGGTCTC„ 1106.NM 003155 ,20,1308,TTGGGGGTGGTCTCAGGGGA„ 1107.NM 00315520, 1302,GTGGTCTCAGGGGAGCAGGG„ 1108.NM^" 00315520,1296,TCAGGGGAGCAGGGGAAAAG„ 1109.NM 00315520, 1290.GAGCAGGGGAAAAGACATGG,,

IHO,NM^" 003155 ,20,1284,GGGAAAAGACATGGCAGAGG„

1111.NM 003155 ,20, 1278.AGACATGGCAGAGGAAGTTG,, 1112.NM 003155 ,20,1272.GGCAGAGGAAGTTGGTAAAA,, 1113,NM 003155 ,20,1266,GGAAGTTGGTAAAAGAGGGT„ 1114.NM 003155 ,20,1260,TGGTAAAAGAGGGTACTTTC„ 1115.NM 003155 ,20, 1254.AAGAGGGTACTTTCTCCTGA,, 1116.NM 003155 ,20, 1248.GTACTTTCTCCTGAGGAGAG,, 1117.NM 003155 ,20,1242,TCTCCTGAGGAGAGGCAGAA„ 1118.NM^" 003155 ,20, 1236.GAGGAGAGGCAGAATGATCA,, 1119.NM 003155 ,20, 1230,AGGCAGAATGATCACATGGA„ 1120.NM 003155 ,20, 1224,AATGATCACATGGATTTTGT„ 1121.NM 003155 ,20, 1218,CACATGGATTTTGTTGGTGG„ 1122,NM~ 003155_: ,20,1212,GATTTTGTTGGTGGGAATGC„ 1123.NM 0031_55; ,20, 1206,GTTGGTGGGAATGCTGCCAT„ 1124.NM 003155. ,20, 1200,GGGAATGCTGCCATTGCAGA„ 1125.NM 003155_: ,20, 11 4,GCTGCCATTGCAGAATGTTG„ 1126.NM 003155_: ,20, 118S,ATTGCAGAATGTTGGGATAT„ 1127.NM 003155_: ,20,1182,GAATGTTGGGATATTGATTA„ 1128.NM^" 003155_: 20,1176,TGGGATATTGATTACAGAAG„ 1129.NM 003155_: 20,1170,ATTGATTACAGAAGCCTAGT„ 1130.NM 003155_: ,20,1164,TACAGAAGCCTAGTTTCATG„ 1131,NM~ 003155_: ,20, 1158,AGCCTAGTTTCATGCAATTT„ 1132.NM 003155_: ,20,1152,GTTTCATGCAATTTTCTTTA„ 1133.NM^" 003155_: ,20,1146.TGCAATTTTCTTTAAGGGGG,, 1134.NM 003155 ,20,1140,TTTCTTTAAGGGGGATAGAA„ 1135,NM^" 003155_: ,20,1134,TAAGGGGGATAGAAAATAGG„ 1136.NM 003155_: ,20, 1128,GGATAGAAAATAGGAACTAC„ 1137.NM 003155_: ,20, 1122,AAAATAGGAACTACTTTAAA„ 1138.NM 003155 ,20, 1116,GGAACTACTTTAAAAAAATC„ 1139.NM 003155 ,20,1110,ACTTTAAAAAAATCAAACCA„ 1140.NM 003155 ,20, 1104,AAAAAATCAAACCAGGCACA„ 1141.NM 003155 ,20, 1098,TCAAACCAGGCACAGTACAC„ 1142,NM 003155 ,20, 1092,CAGGCACAGTACACTCAAAA„ 1143,NM 003155_: ,20, 1086,CAGTACACTCAAAATTGGTG„ 1144.NM 003155 ,20,1080,ACTCAAAATTGGTGTGTCAA„ 1145.NM 003155 ,20, 1074,AATTGGTGTGTCAACACCCC„ 1146.NM 003155 ,20,1068,TGTGTCAACACCCCTAAAAT„ 1147.NM 003155 ,20, 1062,AACACCCCTAAAATGATACT„ 1148,NM 003155 ,20, 1056,CCTAAAATGATACTAGTTTG„ 1149.NM 003155 ,20, 1050,ATGATACTAGTTTGGTGAGG„ 1150.NM 003155 ,20, 1044,CTAGTTTGGTGAGGTTGTGA„ 1151.NM 003155 ,20, 1038.TGGTGAGGTTGTGAATAACC,, H52,NM^" 003155 ,20, 1032,GGTTGTGAATAACCTCTCCC„ 1153.NM^" 003155_: ,20, 1026.GAATAACCTCTCCCTGGTTA,, 1154.NM 003155 ,20,1020,CCTCTCCCTGGTTATGCACT„ 1155,NM~ 003155_: ,20, 1014,CCTGGTTATGCACTCTCATG„ 1156.NM 003155 ,20,1008,TATGCACTCTCATGGGATGT„ 1157,NM 003155_: ,20, 1002,CTCTCATGGGATGTGCGTTT„ 1158.NM 003155 ,20,996,TGGGATGTGCGTTTGATGTG„ 1159.NM^" 003155 ,20,990,GTGCGTTTGATGTGGGAGGG„ 1160,NM^" 003155. ,20,984,TTGATGTGGGAGGGAGAGTC„ 1161,NM.^" 003155 ,20,978,TGGGAGGGAGAGTCCTCCTC„ 1162.NM 003155 ,20,972,GGAGAGTCCTCCTCACCTCG„ 1163.NM 003155 ,20,966,TCCTCCTCACCTCGGAGGTT„ 1164.NM 003155 ,20,960,TCACCTCGGAGGTTCCTGAG„ 1165,NM^" 003155 ,20,954,CGGAGGTTCCTGAGGAGGAC„ 1166.NM 003155 ,20,948,TTCCTGAGGAGGACTTTCAG„ 1167.NM 003155_: ,20,942,AGGAGGACTTTCAGCTTCTG„ 1168.NM 003155_: ,20,936,ACTTTCAGCTTCTGCGGCTC„ 1169.NM 003155 ,20,930,AGCTTCTGCGGCTCATTGGT„ 1170.NM^" 003155 ,20,924,TGCGGCTCATTGGTGCGTCT„ 1171.NM 003155 ,20,918,TCATTGGTGCGTCTCCTGTT„ 1172.NM^" 003155 ,20,912,GTGCGTCTCCTGTTGAAGTC„ 1173.NM 003155 ,20,906,CTCCTGTTGAAGTCAGCTCG„ 1174.NM 003155_: ,20,900,TTGAAGTCAGCTCGTGGGTG„ 1175.NM 003155. ,20,894,TCAGCTCGTGGGTGTGTTTG„ 1176,NM_003155„20,888,CGTGGGTGTGTTTGGGCACA„

1177,NM_003155„20,882,TGTGTTTGGGCACAGTGGTC„

1178,NM_003155„20,876,TGGGCACAGTGGTCTGTCTG„

1179,NM_0031₅₅„20,870,CAGTGGTCTGTCTGCAGGAT„ 1180,NM_00315₅„20,864,TCTGTCTGCAGGATGTGGAA„

1181 ,NM_003155„20,858,TGCAGGATGTGGAAGAGGCT„

1182,NM_003155„20,852,ATGTGGAAGAGGCTGGCCAT„

1183,NM_003155„20,846,AAGAGGCTGGCCATGTTAGG„

1184,NM_003155„20,840,CTGGCCATGTTAGGCCCAAT„ 1185,NM_003155„20,834,ATGTTAGGCCCAATTTTCTC„

1186,NM_003155,,20,828,GGCCCAATTTTCTCCATCAG„

1187,NM_003155„20,822,ATTTTCTCCATCAGGCTGTC„

1188,NM_003155„20,816,TCCATCAGGCTGTCTCTGAT„

1189,NM_003155„20,810,AGGCTGTCTCTGATTGTGCT„ 1190,NM_003155„20,804,TCTCTGATTGTGCTGACTGT„

1191,NM_003155„20,798,ATTGTGCTGACTGTGTCTTC„

1192,NM_003155„20,792,CTGACTGTGTCTTCATCACA„

1193.NM 003155„20,786,GTGTCTTCATCACATTCCAG„

1194.NM 003155„20,780,TCATCACATTCCAGCAGGCT„ 1195,NM_003155„20,774,CATTCCAGCAGGCTTCGGAC„

1196,NM_003155„20,768,AGCAGGCTTCGGACAAGTCT„

1197,NM_003155„20,762,CTTCGGACAAGTCTGTTATA„

1198,NM_003155„20,756,ACAAGTCTGTTATAGTATCT„

1199,NM_003155„20,750,CTGTTATAGTATCTGTTGGA„ 1200,NM_003155„20,744,TAGTATCTGTTGGAGAAGTG„

1201_;NM_003155„20,738,CTGTTGGAGAAGTGATTGGG„

1202.NM 003155„20,732,GAGAAGTGATTGGGCAGCTG„

1203_>NM~003155„20,726,TGATTGGGCAGCTGGACGAC„

1204₎NM_003155„20,720,GGCAGCTGGACGACCTCAGT„ 1205,NM_003155„20,714,TGGACGACCTCAGTGATGGC„

1206,NM_003155„20,708,ACCTCAGTGATGGCTTCAGG„

1207,NM_003155„20,702,GTGATGGCTTCAGGGTTCCG„

1208,NM_003155„20,696,GCTTCAGGGTTCCGCTTGGC„

1209,NM_003155„20,690,GGGTTCCGCTTGGCGATGCT„ 1210,NM_003155„20,684,CGCTTGGCGATGCTGCACAC„

1211,NM_003155„20,678,GCGATGCTGCACACATTCAG„

1212,NM_003155„20,672,CTGCACACATTCAGCTTGCT„

1213,NM_003155„20,666,ACATTCAGCTTGCTGTAGCA„

1214,NM_003155„20,660,AGCTTGCTGTAGCACTCTTC„ 1215,NM_003155„20,654,CTGTAGCACTCTTCCTGCAC„

1216,NM_003155„20,648,CACTCTTCCTGCACCTCAGC„

1217,NM_003155„20,642,TCCTGCACCTCAGCAATCAT„

1218,NM_003155„20,636,ACCTCAGCAATCATCCTTTG„

1219,NM_0031₅₅„20,630,GCAATCATCCTTTGGAAAGT„ 1220,NM_003155„20,624,ATCCTTTGGAAAGTGGAGCA„

1221₎NM_003155„20,618,TGGAAAGTGGAGCACCTCCG„

1222,NM_0031₅5„20,612,GTGGAGCACCTCCGAATGGC„

1223,NM_003155„20,606,CACCTCCGAATGGCGAGGAA„

1224,NM_003155,,20,600,CGAATGGCGAGGAAGACCTT„ 1225,NM_003155„20,594,GCGAGGAAGACCTTGGAGGT„

1226,NM_003155„20,588,AAGACCTTGGAGGTGACCCC„

1227,NM_003155„20,582,TTGGAGGTGACCCCGTTGGC„

1228,NM_003155„20,576,GTGACCCCGTTGGCGATGCA„

1229,NM_003155„20,570,CCGTTGGCGATGCATTTTAA„ 1230,NM_003155„20,564,GCGATGCATTTTAAGCTCTC„

1231,NM_003155„20,558,CATTTTAAGCTCTCTTTGAC„

1232₎NM_003155„20,552,AAGCTCTCTTTGACGAATGC„

1233,NM_00315₅„20,546,TCTTTGACGAATGCTTTTCC„

1234_!NM_00315₅„20,540,ACGAATGCTTTTCCCTGAGT„ 1235_JNM_00315₅„20,534,GCTTTTCCCTGAGTGTCAAA„

1236_JNM_003155„20,528,CCCTGAGTGTCAAATTTAGC„

1237,NM_003155„20,522,GTGTCAAATTTAGCAGCGCT„

1238_JNM_003155„20,516,AATTTAGCAGCGCTGTACAA„

1239_JNM_003155„20,510,GCAGCGCTGTACAAGAAGGA„ 1240,NM_003155„20,504,CTGTACAAGAAGGATTTACA„

1241,NM_003155„20,498,AAGAAGGATTTACAGATGTC„

1242,NM_003155„20,492,GATTTACAGATGTCATACAT„

1243,NM_003155„20,486,CAGATGTCATACATCCCATC„

1244,NM_003155„20,480,TCATACATCCCATCTGTGTC„ 1245,NM_003155„20,474,ATCCCATCTGTGTCACAGGT„

1246,NM_003155„20,468,TCTGTGTCACAGGTGGAGTT„

1247,NM_003155„20,462,TCACAGGTGGAGTTTTCCAG„

1248,NM_003155„20,456,GTGGAGTTTTCCAGGCATGC„

1249,NM_003155„20,450,TTTTCCAGGCATGCAAAAGC„ 1250,NM_003155„20,444,AGGCATGCAAAAGCCCCGCA„ 1251,NM_003155„20,438,GCAAAAGCCCCGCAGCCGAC„

1252,NM_003155„20,432,GCCCCGCAGCCGACCTGTAG„

1253,NM_003155„20,426,CAGCCGACCTGTAGAGCACT„

1254,NM_003155„20,420,ACCTGTAGAGCACTGTTGAG„ 1255,NM_003155„20,414,AGAGCACTGTTGAGGCAACG„

1256,NM_003155„20,408,CTGTTGAGGCAACGAACCAC„

1257,N _003155„20,402,AGGCAACGAACCACTTCAGC„

1258,NM_003155„20,396,CGAACCACTTCAGCTGAGTT„

1259,NM_003155„20,390,ACTTCAGCTGAGTTTTGAGC„ 1260,NM_003155„20,384,GCTGAGTTTTGAGCCGCCAC„

1261,NM_003155„20,378,TTTTGAGCCGCCACTCGGGA„

1262,NM_003155„20,372,GCCGCCACTCGGGATTTCCT„

1263,NM_003155„20,366,ACTCGGGATTTCCTGGGGCT„

1264,NM_003155„20,360,GATTTCCTGGGGCTCACAGA„ 1265,NM_0031₅₅„20,354,CTGGGGCTCACAGAGTCATT„

1266,NM_00315S„20,348,CTCACAGAGTCATTCTGCTC„

1267,NM_003155„20,342,GAGTCATTCTGCTCCGCCTC„

1268,NM_003155„20,336,TTCTGCTCCGCCTCATGGGT„

1269,NM_003155„20,330,TCCGCCTCATGGGTTGCAGA„ 1270,NM_003155„20,324,TCATGGGTTGCAGAAGCACT„

1271 ,NM_003155„20,318,GTTGCAGAAGCACTGATCAC„

1272,NM_003155„20,312,GAAGCACTGATCACCAGCAC„

1273,NM_0031₅₅„20,306,CTGATCACCAGCACCAGAAG„

1274,NM_00 155„20,300,ACCAGCACCAGAAGCACTGC„ 1275,NM_003155„20,294,ACCAGAAGCACTGCTGAGTT„

1276,NM_003155„20,288,AGCACTGCTGAGTTTTGGAG„

1277,NM_003155„20,282,GCTGAGTTTTGGAGCATTCT„

1278,NM_003155„20,276,TTTTGGAGCATTCTCTGAGA„

1279,NM_003155„20,270,AGCATTCTCTGAGAAGTTTC„ 1280,NM_003155„20,264,CTCTGAGAAGTTTCCGCTAA„

1281,NM_003155„20,258,GAAGTTTCCGCTAAGTTGTT„

1282,NM_003155„20,252,TCCGCTAAGTTGTTGGGTTT„

1283,NM_003155„20,246,AAGTTGTTGGGTTTTTTTTT„

1284,NM )03155„20,240,TTGGGTTTTTTTTTTTTCCT„ 1285,NM_003155„20,234,TTTTTTTTTTTCCTGCCCCC„

1286,NM_003155„20,228,TTTTTCCTGCCCCCCTTTCC„

1287,NM_003155„20,222,CTGCCCCCCTTTCCTCTTTC„

1288,NM_003155„20,216,CCCTTTCCTCTTTCCCTCTC„

1289,NMJ)03155„20,210,CCTCTTTCCCTCTCCTGGCT„ 1290.NM 0031₅₅„20,204,TCCCTCTCCTGGCTTGAGTG„

1291,NMJ)031₅₅„20,198,TCCTGGCTTGAGTGAAGATG„

1292,NM_003155„20,192,CTTGAGTGAAGATGTGGATC„

1293,NM_003155„20,186,TGAAGATGTGGATCTGGATA„

1294,NM_003155„20, 180,TGTGGATCTGGATACACTGA„ 1295,NM_003155„20, 174,TCTGGATACACTGAAAGCTT„

1296,NM_003155„20,168,TACACTGAAAGCTTAGGTGA„

1297,NM_003155„20,162,GAAAGCTTAGGTGAGGATTT„

1298,NM_003155„20, 156.TTAGGTGAGGATTTGATGAG,,

1299,NM_003155„20, 150,GAGGATTTGATGAGGATTTT„ 1300,NM_003155„20,144,TTGATGAGGATTTTTTTTTG„

1301,NM_003155„20,138,AGGATTT rTTTTGTTGTTG„

1302,NM_003155„20,132,TTTTTTTGTTGTTGTTGCTG„

1303,NM_0031₅₅„20,126,TGTTGTTGTTGCTGGTGATG„

1304,NM_003155..20, 120,TGTTGCTGGTGATGCTGCTG„ 1305.NM 003155„20,114,TGGTGATGCTGCTGCTGCCA„

1306,NM^'~0031₅₅„20,108,TGCTGCTGCTGCCACCGGTG„

1307,Nlvf 0031₅₅„20, 102,TGCTGCCACCGGTGCCTCCG„

1308,NM_003155„20,96,CACCGGTGCCTCCGCTGCTG„

1309,NM_003155„20,90,TGCCTCCGCTGCTGCTGCTG„ 1310,NM_003155„20,84,CGCTGCTGCTGCTGCTGCCG„

1311,NM_003155„20,78,TGCTGCTGCTGCCGCCGCTG„

1312,NM_003155„20,72,TGCTGCCGCCGCTGCTGCTG„

1313,NM_003155„20,66,CGCCGCTGCTGCTGCTGCTG„

1314,NM_003155„20,60,TGCTGCTGCTGCTGCCACCG„ 1315,NM_003155„20,54,TGCTGCTGCCACCGCCGCTG„

1316,NM_003155„20,48,TGCCACCGCCGCTGCTGCTG„

1317,NM_003155„20,42,CGCCGCTGCTGCTGCTGCTG„

1318,NM_003155„20,36,TGCTGCTGCTGCTGCTGCAG„

1319,NM_003155„20,30,TGCTGCTGCTGCAGTCGCTG„ 1320,NM_003155„20,24,TGCTGCAGTCGCTGCTTCTT„

1321 ,NM_003155„20, 18,AGTCGCTGCTTCTTGCACCT„

1322,NM_003155„20, 12,TGCTTCTTGCACCTCTGGCT„

1323,NM_003155„20,6,TTGCACCTCTGGCTTTTGCA„

1324,NM_001814„20, 1819,GCAGTTATTTTTAAAACTTT„ 1325,NM_001814..20, 1813,ATTTTTAAAACTTTATTTTA„ 1326,NM_001814„20, 1807.AAAACTTTATTTTAAAAATA,,

1327,NM_001814„20, 1801 ,TTATTTTAAAAATATGAGCA„

1328,NM_001814„20, 1795.TAAAAATATGAGCATCTATT,,

1329,NM_001814„20,1789,TATGAGCATCTATTTTAAAA„ 1330,NMJ)01814„20,1783,CATCTATTTTAAAAGTTTTG„

1331 ,NM_001814„20, 1777,TTTTAAAAGTTTTGATAATT„

1332,NM_001814„20, 1771 ,AAGTTTTGATAATTATTGCC„

1333.NM 001814„20,1765,TGATAATTATTGCCATTATT„

1334,NM 001814„20,1759,TTATTGCCATTATTTTCTTG„ 1335,NM_001814„20, 1753,CCATTATTTTCTTGTGATTG„

1336,NM_001814„20,1747,TTTTCTTGTGATTGGTACAA„

1337,NM_001814„20, 1741 ,TGTGATTGGTACAATTTAAA„

1338,NM_001814„20,1735,TGGTACAATTTAAAAATAAG„

1339,NM_001814„20₎1729,AATTTAAAAATAAGTCTATG„ 1340,NM_001814„20, 1723,AAAATAAGTCTATGTTTTCA„

1341₎NM_001814„20,1717,AGTCTATGTTTTCACATTGA„

1342,NM_001814„20, 1711.TGTTTTCACATTGATTTTAA,,

1343,NM_001814„20, 1705,CACATTGATTTTAAAAAATA„

1344,NM_001814„20, 1699,GATTTTAAAAAATATAGCAT„ 1345,NM_001814„20, 1693,AAAAAATATAGCATGTTTGA„

1346,NM_001814„20, 16S7,TATAGCATGTTTGAATTACA„

1347,NM_001814„20, 1681 ,ATGTTTGAATTACAAATGAT„

1348,NM_001814„20,1675,GAATTACAAATGATTAAGCA„

1349,NM_001814„20, 1669,CAAATGATTAAGCAAACTCT„ 1350,NM_001814„20, 1663,ATTAAGCAAACTCTATTACT„

1351 ,NM_001814„20, 1657,CAAACTCTATTACTTCATAG,,

1352,NM_001814„20, 1651 ,CTATTACTTCATAGCTGACC„

1353,NM_001814„20,1645,CTTCATAGCTGACCATCTTC„

1354,NM_001814„20, 1639.AGCTGACCATCTTCCAGAAA,, 1355,NM_001814„20,1633,CCATCTTCCAGAAAATTCCC„

1356,NM_001814„20, 1627,TCCAGAAAATTCCCACTTAA„

1357,NM_001814„20, 1621 ,AAATTCCCACTTAATTGAAT„

1358,NM_001814„20,1615,CCACTTAATTGAATACTTAG„

1359,NM_001814„20, 1609,AATTGAATACTTAGAAAAAA„ 1360,NM_001814„20, 1603,ATACTTAGAAAAAAATGGCC„

1361 ,NM_001814„20, 1597,AGAAAAAAATGGCCAGTGGC„

1362,NM_001814„20, 1591 ,AAATGGCCAGTGGCCGATTG„

1363,NM_001814„20,1585,CCAGTGGCCGATTGAAAGGT„

1364,NM_001814„20,1579,GCCGATTGAAAGGTATATTA„ 1365,NM_001814„20,1573,TGAAAGGTATATTAAAATTA„

1366.NM 001814„20, 1567,GTATATTAAAATTAAGGGCA,,

1367,NM~001814„20, 1561 ,TAAAATTAAGGGCAGTTTTA„

1368.NM )01814„20, 1555,TAAGGGCAGTTTTAATTCTG„

1369,NM_001814„20, 1549,CAGTTTTAATTCTGAAGACA„ 1370,NM_001814„20, 1543,TAATTCTGAAGACAAATATC„

1371 ,NM_001814„20, 1537,TGAAGACAAATATCTTCATG„

1372,NM_001814„20, 1531 ,CAAATATCTTCATGGAAATC„

1373,NM_001814„20, 1525,TCTTCATGGAAATCTATTTG„

1374,NM_001814„20, 1519,TGGAAATCTATTTGTAAGCT„ ^' 1375,NM_001814„20,1513,TCTATTTGTAAGCTTCTGAG„

1376,NM_001814„20, 1507,TGTAAGCTTCTGAGATTGCT,,

1377,NM_001814„20, 1501 ,CTTCTGAGATTGCTGCTGAA„

1378,NM_001814„20,1495,AGATTGCTGCTGAAAGTCTA„

1379,NM_001814..20, 1489,CTGCTGAAAGTCTACAGTCT„ 1380,NM_001814„20, 1483,AAAGTCTACAGTCTGTGAAT„

1381 ,NM_001814„20, 1477/TAC AGTCTGTGAATATACCA,,

1382.NM 001814„20, 1471 ,CTGTGAATATACCAATTCCC„

1383.NM K) 1814„20, 146₅,ATATACCAATTCCCCTTTAC„

1384,NM_001814„20, 1459,CAATTCCCCTTTACAACTGA„ 1385,NM_001814„20, 1453.CCCTTTACAACTGATGCAGA,,

1386,NM_001814„20, 1447.ACAACTGATGCAGATCATTA,,

1387,NM_001814„20, 1441 ,GATGCAGATCATTATGAAAT„

1388,NM_001814„20,1435,GATCATTATGAAATACTGGA„

1389,NM_001814..20, 1429,TATGAAATACTGGAAGGCAT„ 1390,NM_001814„20,1423,ATACTGGAAGGCATACCCTA„

1391,NM_001814„20,1417,GAAGGCATACCCTACAATTT„

1392,NM_001814„20, 1411 , ATACCCTACAATTTAGGAAT,,

1393,NM_001814„20,1405,TACAATTTAGGAATTGGTGT„

1394,NM_001814„20,1399,TTAGGAATTGGTGTGGCTGC„ 1395,NM_001814„20, 1393,ATTGGTGTGGCTGCCACTGC„

1396,NM_001814„20,13S7,GTGGCTGCCACTGCTATGCT„

1397,NM_001814„20,1381,GCCACTGCTATGCTCTCAAT„

1398,NM_001814„20,1375,GCTATGCTCTCAATTGCACA„

1399,NM_001814„20,1369,CTCTCAATTGCACACTCATC„ 1400,NM_001814„20,1363,ATTGCACACTCATCAGTTCC„ 1401,NM_001814„20,1357,CACTCATCAGTTCCTCTGCG„

1402,NM_001814„20, 1351 ,TCAGTTCCTCTGCGGATCCG„

1403,NM_001814„20, 1345,CCTCTGCGGATCCGGAAGTA„

1404,NM_001814„20, 1339,CGGATCCGGAAGTAGCCATT„ 1405,NM_001814„20,1333,CGGAAGTAGCCATTCTCACC„

1406,NM_001814„20, 1327,TAGCCATTCTCACCCCAGCC„

1407.NM 001814„20, 1321 ,TTCTCACCCCAGCCGGTGCC„

1408.NM J)01814„20, 1315,CCCCAGCCGGTGCCCCAGCT„

1409,NM_001814„20,1309,CCGGTGCCCCAGCTGTTTTT„ 1410,NM_001814„20,1303,CCCCAGCTGTTTTTAACAAT„

1411,NM_001814„20,1297,CTGTTTTTAACAATCCAGTA„

1412,NM_001814„20,1291,TTAACAATCCAGTAATCCAT„

1413,NM_001814..20, 1285,ATCCAGTAATCCATCCCAGA„

1414,NM~001814„20,1279,TAATCCATCCCAGAGGCTGA„ 1415,NM_001814„20,1273,ATCCCAGAGGCTGAGTCAGT„

1416,NM_001814„20,1267,GAGGCTGAGTCAGTGCCATA„

1417,NM_001814„20,1261,GAGTCAGTGCCATAGCCCAC„

1418,NM_001814„20, 1255,GTGCCATAGCCCACAAGCAG„

1419,NM_001814„20, 1249,TAGCCCACAAGCAGAACAGC„ 1420,NM_001814„20,1243,ACAAGCAGAACAGCATGATT„

1421 ,NM_001814„20, 1237,AGAACAGCATGATTAGTCAG„

1422,NM_001814„20, 1231 ,GCATGATTAGTCAGCTCAAA„

1423,NM_001814„20, 1225,TTAGTCAGCTCAAAGGGGTT„

1424,NM_001814„20, 1219,AGCTCAAAGGGGTTGAAAGG„ 1425,NM_001814„20,1213,AAGGGGTTGAAAGGGTCTCT„

1426,NM_001814„20, 1207,TTGAAAGGGTCTCTTAGACC„

1427,NM_001814„20, 1201 ,GGGTCTCTTAGACCAGTGTG„

1428,NM_001814„20, 1195.CTTAGACCAGTGTGGTGGTA,,

1429,NM_001814„20, 1189,CCAGTGTGGTGGTAGATCCC„ 1430,NM_001814„20,1183,TGGTGGTAGATCCCCTTTTT„

1431,NM_001814„20,1177,TAGATCCCCTTTTTGTAGTG„

1432,NM_001814„20, 1171 ,CCCTTTTTGTAGTGGAGGAA„

1433,NM_001814„20, 1165,TTGTAGTGGAGGAAGTCATC„

1434,NM_001814„20, 1159,TGGAGGAAGTCATCATATAC„ 1435.NM 001814„20,1153,AAGTCATCATATACTTCAAA„

1436,NM 001814„20,1147,TCATATACTTCAAAAGCAAC„

1437,NM_001814„20,1141,ACTTCAAAAGCAACTGCCAT„

1438,NM_001814„20,1135,AAAGCAACTGCCATGGGCCC„

1439,NM_001814„20,1129,ACTGCCATGGGCCCATGATG„ 1440,NM_001814„20,1123,ATGGGCCCATGATGGACCAA„

1441,NM_001814„20,1117.CCATGATGGACCAACTCAAG,,

1442,NM_001814„20,1111,TGGACCAACTCAAGCTTCAT„

1443,NM_001814„20,1105,AACTCAAGCTTCATCAGGGC„

1444,NM_001814„20, 1099,AGCTTCATCAGGGCTTCATT„ 1445,NM_001814„20, 1093,ATCAGGGCTTCATTGCAGCC„

1446,NM_001814„20, 1087,GCTTCATTGCAGCCTCCATA„

1447,NM_001814„20, 1081 ,TTGCAGCCTCCATAGAAACC„

1448,NM_001814„20,1075,CCTCCATAGAAACCTCCTAC„

1449,NM_001814„20,1069,TAGAAACCTCCTACATAGTG„ 1450,NM_001814„20,1063,CCTCCTACATAGTGGTACTC„

1451 ,NM_001814„20, 1057,ACATAGTGGTACTCAGAGGA„

1452,NM_001814„20, 1051.TGGTACTCAGAGGAGTAATA,,

1453,NM_001814„20, 1045,TCAGAGGAGTAATAACGAAA„

1454,NM_001814„20,1039,GAGTAATAACGAAAGCAGTC„ 1455,NM 001814„20,1033,TAACGAAAGCAGTCTTCCTT„

1456,NM O01814„20,1027,AAGCAGTCTTCCTTCATTTT„

1457,NM 001814„20, 1021 ,TCTTCCTTCATTTTGCATGG„

14₅8,NMI001814„20,101₅,TTCATTTTGCATGGAGAATC„

14₅9,NM_001814„20, 1009,TTGCATGGAGAATCAGTGCC„ 1₄60,NM_001814„20,1003,GGAGAATCAGTGCCTGTGTA„ '

1461 ,NM_001814„20,997,TCAGTGCCTGTGTAGGGGAA„

1462,NM_001814„20,991,CCTGTGTAGGGGAAGCAAGC„

1463,NM_001814„20,985,TAGGGGAAGCAAGCTTCTTC„

1464,NM_001814„20,979,AAGCAAGCTTCTTCCACCAG„ 1465,NM_001814„20,973,GCTTCTTCCACCAGCCCAAA„

1466,NM_001814„20,967,TCCACCAGCCCAAAATCTTG„

1467,NM_001814„20,961,AGCCCAAAATCTTGGGCGTA„

1468,NM_001814„20,955,AAATCTTGGGCGTACTTTCC„

1469,NM_001814„20,949,TGGGCGTACTTTCCTGCAAT„ 1470,NM_001814„20,943,TACTTTCCTGCAATAAGGTA„

1471,NM_001814„20,937,CCTGCAATAAGGTATGGGAA„

1472,NM_001814„20,931 ,ATAAGGTATGGGAAGCCGCC„

1473,NM_001814„20,925,TATGGGAAGCCGCCTTCACA„

1474,NM_001814„20,919,AAGCCGCCTTCACAGCCTTG„ 1475,NM_001814„20,913,CCTTCACAGCCTTGAGCATA„ 1476,NM_001814„20,907,CAGCCTTGAGCATACTGGCT„ 1477,NM_001814„20,901 ,TGAGCATACTGGCTACAAGA„ 1478,NM_001814„20,895,TACTGGCTACAAGACACAAC„ 1479,NM_001814„20,S89,CTACAAGACACAACCTCCTG„ 1480,NM_001814„20,883,GACACAACCTCCTGAGGGCT„

1481 ,NM_001814„20,877,ACCTCCTGAGGGCTTAGGAT„ 1482,NM_001814„20,871.TGAGGGCTTAGGATTGGGGT,, 1483,NM_001814„20,865,CTTAGGATTGGGGTCTGAGA„ 1484,NM_001814„20,8₅9,ATTGGGGTCTGAGAATTGTT„ 148₅,NM_001814„20,8₅3,GTCTGAGAATTGTTGGTTAG;,

1486,NM_001814„20,847,GAATTGTTGGTTAGTATACG„ 1487,NM_001814„20,841 ,TTGGTTAGTATACGGATTCT„ 1488,NM_001814„20,835,AGTATACGGATTCTCGCTTC„ 14S9,NM_001814„20,829,CGGATTCTCGCTTCTAGCAT„ 1490,NM_001814„20,823,CTCGCTTCTAGCATACCCAT„

1491 ,NM_001814„20,817,TCTAGCATACCCATAGAAGC„ 1492,NM_001814„20,811 ,ATACCCATAGAAGCAAATGA„ 1493,NM_001814„20,805,ATAGAAGCAAATGAGTAGCA„ 1494,NM_001814„20,799,GCAAATGAGTAGCAGCTGCC„ 1495,NM_001814„20,793,GAGTAGCAGCTGCCACAGGA„

1496,NM_001814„20,787,CAGCTGCCACAGGATGCTTG„ 1497,NM_001814„20,781 ,CCACAGGATGCTTGGTTTCG„ 1498,NM_001814„20,775,GATGCTTGGTTTCGAACAGG„ 1499,NM_001814„20,769,TGGTTTCGAACAGGACTGAC„ 1500,NM_001814„20,763,CGAACAGGACTGACAAAATT„

1501 ,NM_001814„20,757,GGACTGACAAAATTGATACC„ 1502,NM_001814„20,751 ,ACAAAATTGATACCATGAAC„ 1503,NM_001814„20,745,TTGATACCATGAACATTTCT„ 1504,NM_001814„20,739,CCATGAACATTTCTCCAGTC„ 1505,NM_001814„20,733,ACATTTCTCCAGTCCCAAGA„

1506,NM_001814„20,727,CTCCAGTCCCAAGATGTTGG„ 1507,NM_001814„20,721 ,TCCCAAGATGTTGGCAAATG„ 1508,NM_001814„20,715,GATGTTGGCAAATGCAAAAT„ 1509.NM 001814„20,709,GGCAAATGCAAAATCTTTTG„ 1510,NM )01814„20,703,TGCAAAATCTTTTGCTGTAT„

1511 ,NM_001814„20,697,ATCTTTTGCTGTATTTCAGC„ 1512,NM_001814„20,691 ,TGCTGTATTTCAGCAGTCAG„ 1513,NM_001814„20,685,ATTTCAGCAGTCAGTGGTGC„ 1514,NM_001814„20,679,GCAGTCAGTGGTGCAGGTTT„ 1515,NM_001814„20,673,AGTGGTGCAGGTTTGGGCCT„

1516,NM_001814„20,667,GCAGGTTTGGGCCTTGGGAT„ 1517,NM_001814„20,661 ,TTGGGCCTTGGGATTTTTCG„ 1518,NM_001814„20,655,CTTGGGATTTTTCGACTGTG„ 1519,NM_001814„20,649,ATTTTTCGACTGTGGCCACC„ 1520,NM_001814„20,643,CGACTGTGGCCACCACTTCT„

1521 ,NM_001814„20,637,TGGCCACCACTTCTCCTAAT„ 1522,NM_001814„20,631 ,CCACTTCTCCTAATCATATC„ 1523,NM_001814„20,625,CTCCTAATCATATCTCCCAG„ 1524,NM_001814„20,619,ATCATATCTCCCAGGGTAAG„ 1525,NM_001814„20,613,TCTCCCAGGGTAAGAGTCTC„

1₅26,NM_001814„20,607,AGGGTAAGAGTCTCATATTC„ 1527,NM_001814„20,601 ,AGAGTCTCATATTCCATGTA„ 1528,NM_001814„20,595,TCATATTCCATGTATGTAGT„ 1₅29,NM_001814„20,589,TCCATGTATGTAGTTGCAGT„ 1530,NM_001814„20,583,TATGTAGTTGCAGTCCAAGA„

1531 ,NM_001814„20,577,GTTGCAGTCCAAGACTTCTG„ 1532,NM_001814„20,571 ,GTCCAAGACTTCTGAATGGC„ 1533,NM_001814„20,565,GACTTCTGAATGGCATTGAT„ 1534,NM_001814„20,559,TGAATGGCATTGATAGCTTT„ 1535,NM_001814„20,553,GCATTGATAGCTTTCACAAA„

1536,NM_001814„20,547,ATAGCTTTCACAAAGTTGTG„ 1537,NM_001814„20,541 ,TTCACAAAGTTGTGATCATA„ 1538,NM_001814„20,₅3₅,AAGTTGTGATCATACTTGTA„ 1539,NM_001814„20,529,TGATCATACTTGTAGAGCCT„ 1540,NM_001814„20,523,TACTTGTAGAGCCTATTAGA„

1541 ,NM_001814„20,517,TAGAGCCTATTAGAATACTT„ 1542,NM_001814„20,511 ,CTATTAGAATACTTTTCCTG„ 1543,NM_001814„20,505,GAATACTTTTCCTGAGAATT„ 1544,NM_001814„20,499,TTTTCCTGAGAATTCTTAAG„ 1545,NM_001814„20,493,TGAGAATTCTTAAGGTGTGC„

1546,NM_001814„20,487,TTCTTAAGGTGTGCTGTGTT„ 1547,NM_001814„20,481 ,AGGTGTGCTGTGTTGACATA„ 1548,NM_001814„20,475,GCTGTGTTGACATACACATT„ 1549,NM 001814„20,469,TTGACATACACATTCTCAGA„ 1550,NM )01814„20,463,TACACATTCTCAGAGGCAGT„ 1551 ,NM_001814„20,457,TTCTCAGAGGCAGTTCCCAC„ 1552,NM_001814„20,451 ,GAGGCAGTTCCCACCTTCTT„ 1553,NM_001814„20,445,GTTCCCACCTTCTTTCCGGT„ 1554,NM_001814„20,439,ACCTTCTTTCCGGTGAAACA„ 1555,NM_001814„20,433,TTTCCGGTGAAACAAGCCCA„

1₅₅6,NM_001814„20,427,GTGAAACAAGCCCAGTTCCG„ 1₅₅7,NM_001814„20,421 ,CAAGCCCAGTTCCGGCCCAA„ 1558,NM_001814„20,415,CAGTTCCGGCCCAACACATC„ 1559,NM_001814„20,409,CGGCCCAACACATCATGCAC„ 1560,NM_001814„20,403,AACACATCATGCACCCACCC„

1561 ,NM_001814„20,397,TCATGCACCCACCCAGTCAT„ 1562,NM_001814„20,391 ,ACCCACCCAGTCATTGTCTC„ 1563,NM_001814„20,385,CCAGTCATTGTCTCGTTGCA„ 1564,NM_001814„20,379,ATTGTCTCGTTGCAGTAAGT„ 1565,NM_001814„20,373,TCGTTGCAGTAAGTGGTCAC„

1566,NM_001814„20,367,CAGTAAGTGGTCACCTTGCT„ 1567,NM_001814„20,361 ,GTGGTCACCTTGCTGCCCTC„ 1568,NM_001814„20,355,ACCTTGCTGCCCTCTTCTTT„ 1569,NM 001814„20,349,CTGCCCTCTTCTTTATACTT„ 1570,NM^_001814„20,343,TCTTCTTTATACTTAAAAAA„

1571 ,NM~001814„20,337,TTATACTTAAAAAAGGCAAA„ 1572,NM_001814„20,331 ,TTAAAAAAGGCAAACCACTT„ 1573,NM_001814„20,325,AAGGCAAACCACTTGTAGTC„ 1574,NM_001814„20 ,319, AACCACTTGTAGTCATTCAA,, 1575,NM_001814„20,313,TTGTAGTCATTCAACACAAT„

1576,NM_001814„20,307,TCATTCAACACAATCTCAAA„ 1577,NM_001814„20,301 ,AACACAATCTCAAAGCCTTG„ 1578,NM_001814„20,295,ATCTCAAAGCCTTGGTTGTA„ 1579,NM_001814„20,289,AAGCCTTGGTTGTAAATGAT„ 1580,NM_001814„20,283,TGGTTGTAAATGATGGTGAA„

1581 ,NM_001814„20,277,TAAATGATGGTGAAATGGCC„ 1582,NM_001814„20,271 ,ATGGTGAAATGGCCAGAATT„ 1583,NM_001814„20,265,AAATGGCCAGAATTGCCAAG„ 1584,NM_001814„20,259,CCAGAATTGCCAAGGTCATC„ 1585,NM_001814„20,253,TTGCCAAGGTCATCATATGC„

1586,NM_001814„20,247,AGGTCATCATATGCTGTATC„ 1587,NM_001814„20,241 ,TCATATGCTGTATCCAGCTT„ 1588,NM_001814„20,235,GCTGTATCCAGCTTCTGAAG„ 1589,NM_001814„20,229,TCCAGCTTCTGAAGGTACAC„ 1590,NM_001814„20,223,TTCTGAAGGTACACCACTAC„

1591 ,NM_001814„20,217,AGGTACACCACTACTTTTTT„ 1592,NM_001814„20,211 ,ACCACTACTTTTTTTTCTTG„ 1593.NM 001814„20,205,ACTTTTTTTTCTTGTGGTCC„ 1594.NM J)01814„20, 199,TTTTCTTGTGGTCCCATAAC„ 1595,NM_001814„20, 193,TGTGGTCCCATAACCGAGCA„

1596,NM_001814„20, 187.CCCATAACCGAGCAGTTGAC,, 1597,NM_001814„20, 181 ,ACCGAGCAGTTGACATCGCG„ 1598,NM_001814„20, 175,CAGTTGACATCGCGCTGGGA„ 1599,NM_001814„20, 169,ACATCGCGCTGGGAACCGCT„ 1600,NM_001814„20, 163,CGCTGGGAACCGCTGGAGCC„

1601 ,NM_001814„20, 157,GAACCGCTGGAGCCCACCTG„ 1602,NM_001814„20, 151 ,CTGGAGCCCACCTGGAAGAC„ 1603,NM_001814„20,145,CCCACCTGGAAGACCCAGGT„ 1604,NM_001814„20, 139.TGGAAGACCCAGGTGCCCAG,, 1605,NM_001814„20,133,ACCCAGGTGCCCAGCAGGTC„

1606,NM_001814„20, 127,GTGCCCAGCAGGTCAAGATA„ 1607,NM_001814„20, 121 ,AGCAGGTCAAGATAGGTGCA„ 1608,NM_001814„20, 115,TCAAGATAGGTGCAGTTGGC„ 1609,NM_001814„20, 109,TAGGTGCAGTTGGCAGGTGT„ 1610,NM_001814„20, 103,CAGTTGGCAGGTGTGTCGCA„

1611 ,NM_001814„20,97,GCAGGTGTGTCGCAGCGCAC„ 1612,NM_001814„20,91 ,GTGTCGCAGCGCACGGCGCC„ 1613,NM_001814„20,85,CAGCGCACGGCGCCGTCGCC„ 1614,NM_001814„20,79,ACGGCGCCGTCGCCGGAGAG„ 1615,NM_001814„20,73,CCGTCGCCGGAGAGAAGCAG„

1616,NM_001814„20,67,CCGGAGAGAAGCAGCAGGAG„ 1617,NM_001814„20,61.AGAAGCAGCAGGAGGGCGGC,, 1618,NM 001814„20,55,AGCAGGAGGGCGGCGAGCAG„ 1619,NM~001814„20,49,AGGGCGGCGAGCAGCAAGGA„ 1620,NM_001814„20,43,GCGAGCAGCAAGGAGGGCCC„

1621 ,NM_001814„20,37,AGCAAGGAGGGCCCAGCACC„ 1622,NM 001814„20,31 ,GAGGGCCCAGCACCCATGCT„ 1623,NM 001814„20,25,CCAGCACCCATGCTGCAGGG„ 1624,NM_001814„20, 19,CCCATGCTGCAGGGAGCTGA„ 1625,NM_001814„20, 13,CTGCAGGGAGCTGAGAAAAG„ 1626,NM_001814„20,7,GGAGCTGAGAAAAGAGGTGA„ 1627,NM_001814„20, 1 ,GAGAAAAGAGGTGAAGAATT„ 1628,NM_012334„20,7768,AGCTAGTATCTTTTATTGTC„ 1629,NM_012334„20,7762,TATCTTTTATTGTCAGAACT„ 1630,NM_012334„20,7756,TTATTGTCAGAACTTCTGTG„

1631,NM_012334„20,7750,TCAGAACTTCTGTGAGCCAA„ 1632,NM_012334„20,7744,CTTCTGTGAGCCAACAAACA„ 1633,NM_012334„20,7738,TGAGCCAACAAACAGTTTTG„ 1634,NM_012334„20,7732,AACAAACAGTTTTGCATGGT„ 1635,NM_012334„20,7726,CAGTTTTGCATGGTTGTACA„

1636,NM_012334„20,7720,TGCATGGTTGTACACAAAGG„ 1637,NM_012334„20,7714,GTTGTACACAAAGGGACAAG„ 1638,NM_012334„20,7708,CACAAAGGGACAAGGCAAAT„ 1639,NM_012334„20,7702,GGGACAAGGCAAATTTCTTT„ 1640,NM_012334„20,7696,AGGCAAATTTCTTTTTTCGT„

1641,NM_012334„20,7690,ATTTCTTTTTTCGTGTGGGT„ 1642,NMJ312334„20,7684,TTTTTCGTGTGGGTAGACTT„ 1643,NM_012334„20,7678,GTGTGGGTAGACTTAGTTGG„ 1644,NM_012334„20,7672,GTAGACTTAGTTGGCCCAAG„ 1645,NM_012334„20,7666,TTAGTTGGCCCAAGTCCTTA„

1646,NM_012334„20,7660,GGCCCAAGTCCTTAAAACTT„ 1647,NM_012334„20,7654,AGTCCTTAAAACTTTTCCAT„ 1648,NM_012334„20,7648,TAAAACTTTTCCATATAAAA„ 1649,NM_012334„20,7642,TTTTCCATATAAAAATAAAA„ 16₅0,NM_012334„20,7636,ATATAAAAATAAAAAGTCCA„

1651 ,NM 012334„20,7630,AAATAAAAAGTCCAAGACCA„ 16₅2,NM 012334„20,7624,AAAGTCCAAGACCAGATTAT„ 16₅3,NM_012334„20,7618,CAAGACCAGATTATTTTTCT„ 16₅4,NM_012334„20,7612,CAGATTATTTTTCTTCTGGT„ 16₅₅,NM_012334„20,7606,ATTTTTCTTCTGGTCATAAA„

16₅6,NM_012334„20,7600,CTTCTGGTCATAAATGCTGA„ 1657,NM )12334„20,7594,GTCATAAATGCTGATTTATT„ 1658,NM_012334„20,7588,AATGCTGATTTATTTACAGG„ 1659,NM_012334„20,7582,GATTTATTTACAGGTGCCTT„ 1660,NM_012334„20,7576,TTTACAGGTGCCTTGTTCAG„

1661,NM_012334„20,7570,GGTGCCTTGTTCAGACCACC„ 1662,NM_012334„20,7564,TTGTTCAGACCACCATTATA„ 1663,NM_012334„20,7558,AGACCACCATTATAAACTTG„ 1664,NM_012334„20,7552,CCATTATAAACTTGGGATAA„ 1665,NM_012334„20,7546,TAAACTTGGGATAAAATATG„

1666,NM_012334„20,7540,TGGGATAAAATATGTGTGTA„ 1667,NM_012334„20,7534,AAAATATGTGTGTATTAAAG„ 1668.NM 012334„20,7528,TGTGTGTATTAAAGCCTCAG„ 1669,NM 012334„20,7522,TATTAAAGCCTCAGCATTTA„ 1670,NM_012334„20,7516,AGCCTCAGCATTTAATGTCA„

1671 ,NM_012334„20,7510,AGCATTTAATGTCAGGGTCC„ 1672,NM_012334„20,7504,TAATGTCAGGGTCCTTTGAA„ 1673,NM_012334„20,7498,CAGGGTCCTTTGAAGATTCA„ 1674,NM_012334„20,7492,CCTTTGAAGATTCACTCAAG„ 1675,NM_012334„20,7486,AAGATTCACTCAAGTGTTAA„

1676,NM_012334„20,7480,CACTCAAGTGTTAAGACGTT„ 1677,NM_012334„20,7474,AGTGTTAAGACGTTTCTGGA„ 1678,NM_012334„20,7468,AAGACGTTTCTGGAATGCAG„ 1679,NM_012334„20,7462,TTTCTGGAATGCAGCGTCTC„ 1680,NM_012334„20,7456,GAATGCAGCGTCTCTCCCCC„

1681,NM_012334„20,7450,AGCGTCTCTCCCCCATAGTC„ 1682,NM_012334„20,7444,TCTCCCCCATAGTCAACATG„ 1683,NM_012334„20,7438,CCATAGTCAACATGGTTATT„ 1684,NM_012334„20,7432,TCAACATGGTTATTATATCT„ 1685,NM_012334„20,7426,TGGTTATTATATCTGTAATC„

1686,NM_012334„20,7420,TTATATCTGTAATCTATCCA„ 1687,NM_012334„20,7414,CTGTAATCTATCCAGAATGA„ 1688,NM_012334„20,7408,TCTATCCAGAATGATAGAAG„ 1689,NM_012334„20,7402,CAGAATGATAGAAGCTAACC„ 1690,NM_012334„20,7396,GATAGAAGCTAACCTTCCAA„

1691,NM_012334„20,7390,AGCTAACCTTCCAAGTAACA„ 1692,NM_012334„20,7384,CCTTCCAAGTAACACTTTGT„ 1693,NM_012334„20,7378,AAGTAACACTTTGTTTTTAA„ 1694,NM_012334„20,7372,CACTTTGTTTTTAACTTAAA„ 1695,NM_012334„20,7366,GTTTTTAACTTAAATCTTTT„

1696,NM_012334„20,7360,AACTTAAATCTTTTAGACAT„ 1697,NM_012334„20,7354,AATCTTTTAGACATGAAAGA„ 1698,NM_012334„20,7348,TTAGACATGAAAGACTCCAA„ 1699,NM_012334„20,7342,ATGAAAGACTCCAAAATGAC„ 1700,NM_012334„20,7336,GACTCCAAAATGACTTCATT„ 1701 ,NM_012334„20,7330,AAAATGACTTCATTCTTGTT„

1702,NM_012334„20,7324,ACTTCATTCTTGTTCTAAAA„

1703,NM )12334,,20,7318,TTCTTGTTCTAAAACCAGCA„

1704,NM_012334„20,7312,TTCTAAAACCAGCACTGGAG„ 1705,NM )12334„20,7306,AACCAGCACTGGAGCCAGCT„

I706,NM_012334„20,7300,CACTGGAGCCAGCTGTTGAA„

1707,NM_012334„20,7294,AGCCAGCTGTTGAAGAGTGG„

1708,NM_012334„20,7288,CTGTTGAAGAGTGGTTTATA„

1709,NM_012334„20,7282,AAGAGTGGTTTATAAATACA„ 1710,NM_012334„20,7276,GGTTTATAAATACAGTTATC„

1711 ,NM_012334„20,7270,TAAATACAGTTATCTTGTAG„

1712,NM_012334„20,7264,CAGTTATCTTGTAGGCTGCT„

1713,NM_012334„20,7258,TCTTGTAGGCTGCTTATCTG„

1714,NM_012334„20,7252,AGGCTGCTTATCTGTTTATA„ 1715,NM_012334„20,7246,CTTATCTGTTTATAATACAG„

1716,NM_012334„20,7240,TGTTTATAATACAGCAGACA„

1717,NM_012334„20,7234,TAATACAGCAGACACAGATG„

1718,NM_012334„20,7228,AGCAGACACAGATGGCAGAC„

1719,NM 012334„20,7222,CACAGATGGCAGACTTTGCT„ 1720.NM J) 12334„20,7216,TGGCAGACTTTGCTACATGT„

1721 ,NM_012334„20,7210.ACTTTGCTACATGTAAAACA,,

1722,NM_012334„20,7204,CTACATGTAAAACAATGGAG„

1723,NM_012334„20,7198,GTAAAACAATGGAGTCAACA„

1724,NM_012334„20,7192,CAATGGAGTCAACACGTGTT„ 1725,NM_012334„20,7186,AGTCAACACGTGTTTTTCAA„

1726,NM_012334„20,7180.CACGTGTTTTTCAAAATACA,,

1727,NM_012334„20,7174,TTTTTCAAAATACAGCAAAG„

1728,NM_012334„20,7168,AAAATACAGCAAAGACAGGA„

1729.NMJ) 12334„20,7162,CAGCAAAGACAGGAAAATCC„ 1730,NM_012334„20,7156,AGACAGGAAAATCCAGGATT„

1731 ,NM_012334„20,7150,GAAAATCCAGGATTTGGGTT„

1732,NM_012334„20,7144,CCAGGATTTGGGTTTGTTAA„

1733,NM_012334„20,7138,TTTGGGTTTGTTAATAAAAC„

1734,NM_012334„20,7132 TTGTTAATAAAACCACCTT,, 1735,NM_012334„20,7126,AATAAAACCACCTTATAAAG„

1736,NM_012334„20,7120,ACCACCTTATAAAGTAACAA„

1737,NM_012334„20,7114,TTATAAAGTAACAATTGAGA„

1738,NM )12334„20,7108,AGTAACAATTGAGACTATAG„

1739,NM_012334„20,7102,AATTGAGACTATAGCTCTGC„ 1740,NM_012334„20,7096,GACTATAGCTCTGCATTATT„

1741,NM_012334„20,7090,AGCTCTGCATTATTAAAATA„

1742,NM_012334„20,7084,GCATTATTAAAATATACAGA„

1743,NM_012334„20,7078,TTAAAATATACAGACTGTGT„

1744,NM_012334„20,7072,TATACAGACTGTGTACACCA„ 1745,NM_012334„20,7066,GACTGTGTACACCATTACAC„

1746,NM_012334„20,7060,GTACACCATTACACATCCTT„

1747,NM_012334„20,7054,CATTACACATCCTTTTTCCC„

1748,NM_012334„20,7048,ACATCCTTTTTCCCTTTGCT„

1749₎NM_012334„20,7042,TTTTTCCCTTTGCTTTTTAA„ 1750,NM_012334„20,7036,CCTTTGCTTTTTAATGCTCA₎,

1751 ,NM_012334„20,7030,CTTTTTAATGCTCATGAAAC„

1752.NM 012334„20,7024,AATGCTCATGAAACCATGAT„

1753,NM~012334„20,7018,CATGAAACCATGATTAAAGT„

1754₁NM_012334„20,7012,ACCATGATTAAAGTGTTGAG„ 1755,NM_012334„20,7006,ATTAAAGTGTTGAGTTTATG„

1756,NM_012334„20,7000,GTGTTGAGTTTATGAACACA„

1757,NM_012334„20,6994,AGTTTATGAACACATGCACG„

1758,NM_012334„20,6988,TGAACACATGCACGAACAGG„

1759,NM_012334„20,6982,CATGCACGAACAGGCAAGCA„ 1760,NM_012334„20,6976,CGAACAGGCAAGCACGTACA„

1761 ,NM_012334„20,6970,GGCAAGCACGTACACTTAAA„

1762,NM_012334„20,6964,CACGTACACTTAAAAGATGA„

1763,NM_012334„20,6958,CACTTAAAAGATGAAACAAA„

1764,NM_012334„20,6952,AAAGATGAAACAAAGAAAAA„ 1765,NM_012334„20,6946,GAAACAAAGAAAAAAGTTGA„

1766,NM_012334„20,6940,AAGAAAAAAGTTGATTCATG„

1767,NM_012334„20,6934,AAAGTTGATTCATGTCATTC„

1768,NM_012334„20,6928,GATTCATGTCATTCCATGAG„

1769,NM_012334„20,6922,TGTCATTCCATGAGAAAGGC„ 1770,NM_012334„20,6916,TCCATGAGAAAGGCTGCCCG„

1771 ,NM_012334„20,6910,AGAAAGGCTGCCCGCAGCAC„

1772₁NM_012334„20,6904,GCTGCCCGCAGCACTCCAGC„

1773₁NM_012334„20,6898,CGCAGCACTCCAGCTCAAAC„

1774₁NM_012334„20,6892,ACTCCAGCTCAAACACACTG„ 1775₎NM_012334„20,6886,GCTCAAACACACTGTCCCCT„ 1776,NMJH2334„20,6880,ACACACTGTCCCCTCGAGCT„ 1777,NM_012334„20,6874,TGTCCCCTCGAGCTCTCCAT„ 1778,NM_012334„20,6868,CTCGAGCTCTCCATCCCCCT„ 1779,NM_012334„20,6862,CTCTCCATCCCCCTTCCCAC„ 17S0,NM_012334„20,6856,ATCCCCCTTCCCACTCCCTC„

1781,NM_012334„20,6850,CTTCCCACTCCCTCACCTTC„ 1782,NM_012334„20,6844,ACTCCCTCACCTTCCCTCAG„ 1783,NM_012334„20,6838,TCACCTTCCCTCAGATTCGG„ 1784,NM_012334„20,6832,TCCCTCAGATTCGGGGAAAT,, 1785,NM_012334„20,6826,AGATTCGGGGAAATCAGGTT„

1786,NM_012334„20,6820,GGGGAAATCAGGTTGGGAGG„ 1787,NM_012334„20,6814,ATCAGGTTGGGAGGTTAGTG„ 1788,NM_012334„20,6808,TTGGGAGGTTAGTGCATCAT„ 1789,NM_012334„20,6802,GGTTAGTGCATCATTGACAG„ 1790,NM_012334„20,6796,TGCATCATTGACAGAGAATG„

1791,NM_012334„20,6790,ATTGACAGAGAATGCCCCCC„ 1792.NM 012334„20,6784,AGAGAATGCCCCCCTTCCAC„ 1793,NMl012334„20,6778,TGCCCCCCTTCCACGCTCTG,, 1794,NM_012334„20,6772,CCTTCCACGCTCTGTTAAGT„ 1795,NM_012334„20,6766,ACGCTCTGTTAAGTCTCCCC„

1796,NM_012334„20,6760,TGTTAAGTCTCCCCCAGAAG„ 1797.NM 012334„20,6754,GTCTCCCCCAGAAGGGGGAA„ 1798,NM~012334„20,6748,CCCAGAAGGGGGAAAGGCAG„ 1799,NM^_012334„20,6742,AGGGGGAAAGGCAGTTCCCT„ 1800,NMlθl2334,,20,6736,AAAGGCAGTTCCCTTCAGTA„

1801 ,NM_012334„20,6730,AGTTCCCTTCAGTAGCACAG„ 1802,NM_012334„20,6724,CTTCAGTAGCACAGTTACGG„ 1803,NM_012334„20,6718,TAGCACAGTTACGGTCGATT„ 1804,NM_012334„20,6712,AGTTACGGTCGATTAGTGTT„ 1805,NM_012334„20,6706,GGTCGATTAGTGTTGGTTCC„

1806,NM_012334„20,6700,TTAGTGTTGGTTCCACAAGT„ 1807,NM_012334„20,6694,TTGGTTCCACAAGTTAAGGC„ 1808,NM_012334„20,6688,CCACAAGTTAAGGCACTTCC„ 1809,NM_012334„20,6682,GTTAAGGCACTTCCGGCTGC„ 1810,NM_012334„20,6676,GCACTTCCGGCTGCTTTGGT„

1811,NM 012334„20,6670,CCGGCTGCTTTGGTGGCAGC„ 1812,NM~012334„20,6664,GCTTTGGTGGCAGCGTGGTT„ 1813,NM_012334„20,6658,GTGGCAGCGTGGTTCCTCCC„ 1814,NM_012334„20,6652,GCGTGGTTCCTCCCCTCCTT„ 1815,NM_012334„20,6646,TTCCTCCCCTCCTTTTTTAA„

1816,NM_012334„20,6640,CCCTCCTTTTTTAAGGCATG„ 1817,NM_012334„20,6634,TTTTTTAAGGCATGTGTCCT„ 1818,NM_012334„20,6628,AAGGCATGTGTCCTCTAAGA„ 1819,NM_012334„20,6622,TGTGTCCTCTAAGAGTAGTA„ 1820,NM_012334„20,6616,CTCTAAGAGTAGTAAAGCTT„

1821 ,NM_012334„20,6610.GAGTAGTAAAGCTTTGGAAA,, 1822,NM_012334„20,6604,TAAAGCTTTGGAAACTGTGC„ 1823,NM_012334„20,6598,TTTGGAAACTGTGCAGACTG„ 1824,NM_012334„20,6592,AACTGTGCAGACTGTTAAAG„ 1825,NM_012334„20,6586,GCAGACTGTTAAAGTTGACA„

1 S26,NM_012334„20,6580,TGTTAAAGTTGACAGCTTAA„ 1827,NM_012334„20,6574,AGTTGACAGCTTAATACAGG„ 1828,NM_012334„20,6568,CAGCTTAATACAGGATCAAT„ 1829,NM_012334„20,6562,AATACAGGATCAATGAAGGC„ 1830,NM_012334„20,6556,GGATCAATGAAGGCGGCAGG„

1831 ,NM_012334„20,6550,ATGAAGGCGGCAGGCAAAAG„ 1832,NM_012334„20,6544,GCGGCAGGCAAAAGGATCCT„ 1833,NM_012334„20,6538,GGCAAAAGGATCCTCGGAGA„ 1834,NM_012334„20,6532,AGGATCCTCGGAGACACCTC„ 1835.NM 012334„20,6526,CTCGGAGACACCTCCCTCAG„

1836,NMI012334„20,6520,GACACCTCCCTCAGACCAGA„ 1837,NM_012334„20,6514,TCCCTCAGACCAGAAGCTTC„ 1838,NM_012334„20,6₅08,AGACCAGAAGCTTCCAGAAA„ 1839,NM_012334„20,6₅02,GAAGCTTCCAGAAAGCCTGG„ 1840,NM_012334„20,6496,TCCAGAAAGCCTGGGCAGCT„

1841,NM_012334„20,6490,AAGCCTGGGCAGCTCTGTGT„ 1842,NM_012334„20,6484,GGGCAGCTCTGTGTTTGTTT„ 1843,NM_012334„20,6478,CTCTGTGTTTGTTTTGGCTG„ 1844,NM_012334„20,6472,GTTTGTTTTGGCTGGGCATG„ 1845,NM_012334„20,6466,TTTGGCTGGGCATGGCACAC„

1846,NM_012334„20,6460,TGGGCATGGCACACTGGAGC„ 1847,NM_012334„20,6454,TGGCACACTGGAGCCAGCCT„ 1848,NM_012334„20,6448,ACTGGAGCCAGCCTAGGCCA„ 1849,NM_012334„20,6442,GCCAGCCTAGGCCAGAGGGT„ 1850,NM_012334„20,6436,CTAGGCCAGAGGGTGGTGCG„ 1851 ,NM_012334„20,6430,CAGAGGGTGGTGCGTTCAGG„ 1852,NM_012334„20,6424,GTGGTGCGTTCAGGTAGCAA„ 1853,NM_012334„20,6418,CGTTCAGGTAGCAAAGACAG„ 1854.NM 012334„20,6412,GGTAGCAAAGACAGGTGGGC„ 1855,NM )12334„20,6406,AAAGACAGGTGGGCTCTGTC„

1856,NM_012334„20,6400,AGGTGGGCTCTGTCCCGCCT„ 1857,NM )12334„20,6394,GCTCTGTCCCGCCTTCACCT„ 1858,NM_012334„20,6388,TCCCGCCTTCACCTGGAGCT„ 1859,NM_012334„20,6382,CTTCACCTGGAGCTGCCCTG„ 1860,NM_012334„20,6376,CTGGAGCTGCCCTGGCTGCT„

1861 ,NM_012334„20,6370,CTGCCCTGGCTGCTGGCGGA„ 1862,NM_012334„20,6364,TGGCTGCTGGCGGAGCGTGT„ 1863,NM_012334„20,6358,CTGGCGGAGCGTGTCGTGCT„ 1864,NM_012334„20,63₅2,GAGCGTGTCGTGCTGTAGCG„ 1865,NM_012334„20,6346,GTCGTGCTGTAGCGCTTCTT„

1866,NM_012334„20,6340,CTGTAGCGCTTCTTCACGAT„ 1867,NM_012334„20,6334,CGCTTCTTCACGATCATGCT„ 1868,NM_012334„20,6328,TTCACGATCATGCTGATGTA„ 1869,NM_012334„20,6322,ATCATGCTGATGTAGGCTTT„ 1870,NM_012334„20,6316,CTGATGTAGGCTTTCATGAG„

1871 ,NM_012334„20,6310,TAGGCTTTCATGAGCTTGGC„ 1872,NM_012334„20,6304,TTCATGAGCTTGGCCACATC„ 1873,NM_012334„20,6298,AGCTTGGCCACATCCACCAC„ 1874,NM_012334„20,6292,GCCACATCCACCACCTCACT„ 1875,NM_012334„20,6286,TCCACCACCTCACTGGTTTC„

1876,NM_012334„20,6280,ACCTCACTGGTTTCAAAGAG„ 1877,NM_012334„20,6274,CTGGTTTCAAAGAGCAGCTC„ 1878₎NM_012334„20,6268,TCAAAGAGCAGCTCCCTCTC„ 1879,NM_012334„20,6262,AGCAGCTCCCTCTCATCGAC„ 1880,NM_012334„20,6256,TCCCTCTCATCGACCACGAT„

1881 ,NM_012334„20,6250,TCATCGACCACGATCTTATA„ 1882,NM_012334„20,6244,ACCACGATCTTATACGTATT„ 1883,NM_012334„20,6238,ATCTTATACGTATTCGCCAG„ 1884,NM_012334„20,6232,TACGTATTCGCCAGGGGTGC„ 1885,NM_012334„20,6226,TTCGCCAGGGGTGCCCCAAA„

1886,NM_012334„20,6220,AGGGGTGCCCCAAAAGAGAG„ 1887,NM_012334„20,6214,GCCCCAAAAGAGAGGATGTG„ 1888,NM_012334„20,6208,AAAGAGAGGATGTGTTCATA„ 1889,NM_012334„20,6202,AGGATGTGTTCATACTGGAA„ 1890,NM_012334„20,6196,TGTTCATACTGGAAGACTTC„

1891 ,NM_012334„20,6190,TACTGGAAGACTTCCAGTGG„ 1892,NM_012334„20,6184,AAGACTTCCAGTGGTCTTCC„ 1893,NM_012334„20,6178,TCCAGTGGTCTTCCCTCTCC„ 1894,NM_012334„20,6172,GGTCTTCCCTCTCCACGCTT„ 1895,NM_012334„20,6166,CCCTCTCCACGCTTGTAGAC„

1896,NM_012334„20,6160,CCACGCTTGTAGACGGAGAC„ 1897,NM_012334„20,6154,TTGTAGACGGAGACGGCGTC„ 1898,NM_012334„20,6148,ACGGAGACGGCGTCCGCGCT„ 1899,NM_012334„20,6142,ACGGCGTCCGCGCTGACACC„ 1900,NM_012334„20,6136,TCCGCGCTGACACCCAACCA„

1901 ,NM_012334„20,6130,CTGACACCCAACCAGAGTTC„ 1902,NM_012334„20,6124,CCCAACCAGAGTTCCTGAGG„ 1903,NM_012334„20,6118,CAGAGTTCCTGAGGGAAGCC„ 1904.NM 012334„20,6112,TCCTGAGGGAAGCCACCTTC„ 1905,NMJ)12334„20,6106,GGGAAGCCACCTTCCTTGCA„

1906₎NM_012334„20,6100,CCACCTTCCTTGCACTCCAC„

1907,NM_012334„20,6094,TCCTTGCACTCCACATCAAA„ 1908,NM_012334„20,6088,CACTCCACATCAAACAGCGT„

1909,NM_012334„20,6082,ACATCAAACAGCGTCGAGCC„ 1910,NM_012334„20,6076,AACAGCGTCGAGCCATAGCC„

1911 ,NM_012334„20,6070,GTCGAGCCATAGCCAGGCCA„ 1912.NM 012334„20,6064,CCATAGCCAGGCCACTCCTT„ 1913,NM^_012334„20,6058,CCAGGCCACTCCTTGATCAA„ 1914,NM-012334„20,6052,CACTCCTTGATCAAGGCCAT„ 1915,NM O 12334„20,6046,TTGATCAAGGCCATGTACTT„

1916,NM_012334„20,6040,AAGGCCATGTACTTGGCCAT„ 1917,NM_012334„20,6034,ATGTACTTGGCCATGGCCTG„ 1918,NM_012334„20,6028,TTGGCCATGGCCTGTTCCTG„ 1919,NM_012334„20,6022,ATGGCCTGTTCCTGGTTCAT„ 1920,NM_012334„20,6016,TGTTCCTGGTTCATTCCCTG„

1921 ,NM_012334„20,6010,TGGTTCATTCCCTGAAATTT„ 1922,NM_012334„20,6004,ATTCCCTGAAATTTCCTCCA„ 1923,NM_012334„20,5998,TGAAATTTCCTCCACTTGTC„ 1924,NM_012334„20,5992,TTCCTCCACTTGTCAATGAT„ 1925,NM_012334„20,5986,CACTTGTCAATGATACTGGC„ 1926,NM_012334„20,5980,TCAATGATACTGGCTCGAGC„ 1927,NM_012334„20,5974,ATACTGGCTCGAGCAGAGGA„ 1928,NM_012334„20,5968,GCTCGAGCAGAGGAGACTTC„ 1929,NM_012334„20,5962,GCAGAGGAGACTTCTTCCTT„ 1930,NM_012334„20,5956,GAGACTTCTTCCTTAATCCA„

1931,NM_012334„20,5950,TCTTCCTTAATCCACATGTC„ 1932,NM_012334„20,5944,TTAATCCACATGTCCAGCAT„ 1933,NM_012334„20,5938,CACATGTCCAGCATCTGCTC„ 1934,NM_012334„20,5932,TCCAGCATCTGCTCCTCCTC„ 1935,NM_012334„20,5926,ATCTGCTCCTCCTCGACCTT„

1936,NM_012334„20,5920,TCCTCCTCGACCTTCTGCCG„ 1937,NM_012334„20,5914,TCGACCTTCTGCCGGACCAC„ 1938,NM_012334„20,5908,TTCTGCCGGACCACGGATCC„ 1939,NM_012334„20,5902,CGGACCACGGATCCTGTCCG„ 1940,NM_012334„20,₅896,ACGGATCCTGTCCGGAAGCT„

1941 ,NM_012334„20,₅890,CCTGTCCGGAAGCTCCGCCT„ 1942,NM_012334„20,₅884,CGGAAGCTCCGCCTCAGGGT„ 1943,NM_012334„20,₅878,CTCCGCCTCAGGGTCCCCTC„ 1 44,NM_012334„20,₅872,CTCAGGGTCCCCTCTAGGAA„ 1945,NM_012334„20,5866,GTCCCCTCTAGGAAGCTCGT„

1946,NM_012334„20,5860,TCTAGGAAGCTCGTCCGCCT„ 1947,NM_012334„20,5854,AAGCTCGTCCGCCTCTTCTC„ 1948,NM_012334„20,5848,GTCCGCCTCTTCTCCAGCCG„ 1949,NM_012334„20,5842,CTCTTCTCCAGCCGTTCACA„ 1950,NM_012334„20,5836,TCCAGCCGTTCACAAGGGGT„

1951,NM_012334„20,5830,CGTTCACAAGGGGTGAAGGT„ 1952,NM_012334„20,5824,CAAGGGGTGAAGGTTTTGGT„ 1953,NM_012334„20,5818,GTGAAGGTTTTGGTTGACTG„ 1954,NM_012334„20,5812,GTTTTGGTTGACTGGCTGAT„ 1955,NM_012334„20,5806,GTTGACTGGCTGATGCGGGC„

1956,NM_012334„20,5800,TGGCTGATGCGGGCCTTGAG„ 1957,NM_012334„20,5794,ATGCGGGCCTTGAGTCTCTG„ 1958,NM_012334„20₎5788,GCCTTGAGTCTCTGCAGGGA„ 1959,NM_012334„20,5782,AGTCTCTGCAGGGAATAAAC„ 1960,NM_012334„20,5776,TGCAGGGAATAAACCTCTTC„

1961 ,NM_012334„20,5770,GAATAAACCTCTTCGAGAGG„ 1962,NM_012334„20,5764,ACCTCTTCGAGAGGTGGGAT„ 1963,NM_012334„20,5758,TCGAGAGGTGGGATGGCAGC„ 1964,NM_012334„20,57₅2,GGTGGGATGGCAGCGTGCAG„ 196₅,NM_012334„20,5746,ATGGCAGCGTGCAGAGTATA„

1966,NM_012334„20,5740,GCGTGCAGAGTATAATCCCC„ 1967,NM_012334„20,₅734,AGAGTATAATCCCCCTGCAG„ 1968,NM_012334„20,₅728,TAATCCCCCTGCAGATACTG„ 1969,NM_012334„20,₅722,CCCTGCAGATACTGGAGTCG„ 1970,NM_012334„20,5716,AGATACTGGAGTCGCAGGGC„

1971 ,NM_012334„20,₅710.TGGAGTCGCAGGGCAGCAAG,, 1972,NM_012334„20,5704,CGCAGGGCAGCAAGAACCTG„ 1973,NM_012334„20,₅698,GCAGCAAGAACCTGGAGGTT„ 1974,NM_012334„20,₅692,AGAACCTGGAGGTTTTCTTC„ 1975,NM_012334„20,5686,TGGAGGTTTTCTTCCGGGGC„

1976,NM_012334„20,5680,TTTTCTTCCGGGGCTGGATG„ 1977,NM_012334„20,5674,TCCGGGGCTGGATGGTGGCC„ 1978,NM_012334„20,5668,GCTGGATGGTGGCCATGGAT„ 1979,NM_012334„20,5662,TGGTGGCCATGGATAACCGC„ 1980,NM 012334„20,5656,CCATGGATAACCGCTTCGTG„

1981 ,NM ) 12334„20,5650,ATAACCGCTTCGTGGGCCTG„ 1982.NM 012334„20,5644,GCTTCGTGGGCCTGTTCAAA„ 1983,NM )12334„20,5638,TGGGCCTGTTCAAACATAAA„ 1984,NM_012334„20,5632,TGTTCAAACATAAATGCAAA„ 1985,NM_012334„20,5626,AACATAAATGCAAACTCCAC„

1986,NM_012334„20,5620,AATGCAAACTCCACACTGTC„ 1987,NM_012334„20,5614,AACTCCACACTGTCTTTTGG„ 1988,NM_012334„20,5608,ACACTGTCTTTTGGCACGTT„ 1989,NM_012334„20,5602,TCTTTTGGCACGTTGTCTGT„ 1990,NM_012334„20,5596,GGCACGTTGTCTGTGTCCAG„

1991 ,NM 012334„20,5590,TTGTCTGTGTCCAGGAAGCA„ 1992,NM~012334„20,5584,GTGTCCAGGAAGCAGTAAAG„ 1993,NMl012334„20,5578,AGGAAGCAGTAAAGTTTGAA„ 1994,NM_012334„20,5572,CAGTAAAGTTTGAAGTAGAA„ 1995,NM_012334„20,5566,AGTTTGAAGTAGAATTTCCA„

1996,NM_012334„20,5560,AAGTAGAATTTCCATGGCAG„ 1997,NM_012334„20,5554,AATTTCCATGGCAGGTCCCC„ 1998,NM_012334„20,5548,CATGGCAGGTCCCCAACCTC„ 1999,NM 012334„20,5542,AGGTCCCCAACCTCGGATGT„ 2000,NM~012334„20,5536,CCAACCTCGGATGTGGCAGC„ 2001 ,NM_012334„20,5530,TCGGATGTGGCAGCCAGCTT„

2002,NM_012334„20,5524,GTGGCAGCCAGCTTTTCAAA„

2003,NM_012334„20,5518,GCCAGCTTTTCAAACTTGGC„

2004,NM_012334„20,5512,TTTTCAAACTTGGCTAAGAC„ 2005,NM_012334„20,5506,AACTTGGCTAAGACATCAGC„

2006,NM_012334„20,5500,GCTAAGACATCAGCTACGAC„

2007,NM_012334„20,5494,ACATCAGCTACGACGGTTCG„

2008,NM_012334„20,5488,GCTACGACGGTTCGACTTTC„

2009,NM_012334„20,5482,ACGGTTCGACTTTCAATGGC„ 2010,NM_012334„20,5476,CGACTTTCAATGGCTTTGTC,,

2011 ,NM_012334„20,5470,TCAATGGCTTTGTCGACGTG„

2012,NM_012334„20,5464,GCTTTGTCGACGTGGCCGTT„

2013,NM_012334„20,5458,TCGACGTGGCCGTTGTATTC„

2014,NM_012334„20,5452,TGGCCGTTGTATTCAAACAA„ 2015,NM_012334„20,5446,TTGTATTCAAACAAAGCAAA„

2016,NM_012334„20,5440,TCAAACAAAGCAAACATGTT„

2017,NM_012334„20,5434,AAAGCAAACATGTTCCTGCT„

2018,NM_012334„20,5428,AACATGTTCCTGCTGTCCTC„

2019,NM_012334„20,5422,TTCCTGCTGTCCTCCATGGC„ 2020,NM_012334„20,5416,CTGTCCTCCATGGCCAGGCC„

2021,NM_012334„20,5410,TCCATGGCCAGGCCTCGGAT„

2022,NM_012334,,20,5404,GCCAGGCCTCGGATCAGCTT„

2023,NM_012334„20,5398,CCTCGGATCAGCTTCTCCAC„

2024,NM_012334„20,5392,ATCAGCTTCTCCACCACCTC„ 2025,NM_012334„20,5386,TTCTCCACCACCTCCCCAGC„

2026,NM_012334„20,5380,ACCACCTCCCCAGCAGTGGT„

2027,NM_012334„20,5374,TCCCCAGCAGTGGTGTGGGA„

2028,NM_012334„20,5368,GCAGTGGTGTGGGAGTTGAT„

2029,NM_012334„20,5362,GTGTGGGAGTTGATGGTGAT„ 2030,NM_012334„20,5356,GAGTTGATGGTGATCTTGCA„

2031,NM_012334„20,5350,ATGGTGATCTTGCAGGAGCC„

2032,NM_012334„20,₅344,ATCTTGCAGGAGCCGCCGCC„

2033,NM_012334„20,5338,CAGGAGCCGCCGCCATGGCA„

2034,NM_012334„20,5332,CCGCCGCCATGGCAATAGAC„ 2035,NM_012334„20,5326,CCATGGCAATAGACCGTGGA„

2036,NM_012334„20,5320,CAATAGACCGTGGATGTCAT„

2037,NM_012334„20,5314,ACCGTGGATGTCATTTCCTG„

2038,NM_012334„20,5308,GATGTCATTTCCTGCCTGTG„

2039,NM_012334„20,5302,ATTTCCTGCCTGTGGATCAG„ 2040,NM_012334„20,5296,TGCCTGTGGATCAGAGCTTC„

2041,NM_012334„20,5290,TGGATCAGAGCTTCTATTTC„

2042,NM_012334„20,5284,AGAGCTTCTATTTCATCTCG„

2043,NM_012334„20,5278,TCTATTTCATCTCGGGAAGG„

2044,NM_012334„20,5272,TCATCTCGGGAAGGCACAAA„ 2045,NM_012334„20,5266,CGGGAAGGCACAAACTCTCG„

2046,NM_012334„20,5260,GGCACAAACTCTCGGCATTT„

2047,NM_012334„20,5254,AACTCTCGGCATTTGGTTTT_J,

2048,NM_012334„20,5248,CGGCATTTGGTTTTCTTAAG„

2049,NM_012334„20,5242,TTGGTTTTCTTAAGAGATTC„ 2050,NM_012334„20,5236,TTCTTAAGAGATTCGTAAGT„

2051,NM_012334„20,5230,AGAGATTCGTAAGTGAAGAG„

2052,NM_012334„20,5224,TCGTAAGTGAAGAGAGCGTA„

2053,NM_012334„20,5218,GTGAAGAGAGCGTATTTTTC„

2054,NM_012334„20,5212,AGAGCGTATTTTTCCATCTC„ 2055,NM_012334„20,5206,TATTTTTCCATCTCGGTTCC„

2056,NM_012334„20,5200,TCCATCTCGGTTCCTGGAAA„

2057,NM_012334„20,5194,TCGGTTCCTGGAAACTGTTC„

2058,NM_012334„20,5188,CCTGGAAACTGTTCCCGTAT„

2059,NM_012334„20,5182,AACTGTTCCCGTATCCTTTT„ 2060,NM_012334„20,5176,TCCCGTATCCTTTTCAGATG„

2061,NM_012334„20,5170,ATCCTTTTCAGATGGAACTT„

2062,NM_012334„20,5164,TTCAGATGGAACTTGAGATA„

2063,NM_012334„20,5158,TGGAACTTGAGATACTTGAG„

2064,NM_012334„20,5152,TTGAGATACTTGAGAATCCC„ 2065,NM_012334„20,5146,TACTTGAGAATCCCTCGACT„

2066,NM_012334„20,5140,AGAATCCCTCGACTCGGCAG„

2067,NM_012334„20,5134,CCTCGACTCGGCAGGAAGGT„

2068,NM_012334„20,5128,CTCGGCAGGAAGGTGCAGCT„

2069,NM_012334„20,5122,AGGAAGGTGCAGCTCAGGCA„ 2070,NM_012334„20,5116,GTGCAGCTCAGGCATGTCAG„

2071 ,NM_012334„20,5110,CTCAGGCATGTCAGGATCTG„

2072,NM_012334„20,5104,CATGTCAGGATCTGCCAGCT„

2073,NM_012334„20,5098,AGGATCTGCCAGCTGTACAG„

2074,NM_012334„20,5092,TGCCAGCTGTACAGGTTGCC„ 2075,NM_012334„20,5086,CTGTACAGGTTGCCCACACT„ 2076,NM_012334„20,5080,AGGTTGCCCACACTGCCGGG„ 2077,NM_012334„20,5074,CCCACACTGCCGGGGTGGGG„ 2078,NM_012334„20,5068,CTGCCGGGGTGGGGCACTTT„ 2079,NM_012334„20,₅062,GGGTGGGGCACTTTGTTGGT„ 2080,NM_012334„20,₅056,GGCACTTTGTTGGTCTGTTT„

2081,NM_012334„20,5050,TTGTTGGTCTGTTTGATAAG„ 2082,NM_012334„20,5044,GTCTGTTTGATAAGCTGGCA„ 2083,NM_012334„20,₅038,TTGATAAGCTGGCAGTACAG„ 2084,NM_012334„20,₅032,AGCTGGCAGTACAGCTCGTC„ 208₅,NM_012334„20,₅026,CAGTACAGCTCGTCCCGCAG„

2086,NM_012334„20,₅020,AGCTCGTCCCGCAGAGGTCG„ 2087,NM_012334„20,₅014,TCCCGCAGAGGTCGCAGGTC„ 2088,NM_012334„20,500S,AGAGGTCGCAGGTCATGCCC„ 2089,NM_012334„20,5002,CGCAGGTCATGCCCTGTCTG„ 2090,NM_012334„20,4996,TCATGCCCTGTCTGTAGGAT„

2091,NM_012334„20,4990,CCTGTCTGTAGGATGCCCTG„ 2092,NM_012334„20,4984,TGTAGGATGCCCTGGATTAT„ 2093,NM_012334„20,4978,ATGCCCTGGATTATTGGAAT„ 2094,NM_012334„20,4972,TGGATTATTGGAATTGGGTC„ 2095,NM_012334„20,4966,ATTGGAATTGGGTCAGACAT„

2096,NM_012334„20,4960,ATTGGGTCAGACATGGACTC„ 2097,NM_012334„20,4954,TCAGACATGGACTCCAGTTG„ 2098,NM_012334„20,4948,ATGGACTCCAGTTGCTGCAG„ 2099,NM_012334„20,4942,TCCAGTTGCTGCAGGGAATT„ 2100,NM_012334„20,4936,TGCTGCAGGGAATTGAATAT„

2101,NM_012334„20,4930,AGGGAATTGAATATCTTGAT„ 2102,NM_012334„20,4924,TTGAATATCTTGATGGCCTC„ 2103,NM_012334„20,4918,ATCTTGATGGCCTCATCCTG„ 2104,NM_012334„20,4912,ATGGCCTCATCCTGAAGGGT„ 2105,NM_012334„20,4906,TCATCCTGAAGGGTGGTATA„

2106,NM_012334„20,4900,TGAAGGGTGGTATAGCCTTT„ 2107,NM_012334„20,4894,GTGGTATAGCCTTTGTCTTT„ 2108,NM_012334„20,4888,TAGCCTTTGTCTTTGAGCAA„ 2109,NM_012334„20,4882,TTGTCTTTGAGCAAGTTGAG„ 2110,NM_012334„20,4876,TTGAGCAAGTTGAGATTTAT„

2111,NM_012334„20,4870,AAGTTGAGATTTATGTCCCC„ 2112,NM_012334„20,4864,AGATTTATGTCCCCATACGG„ 2113,NM_012334„20,4858,ATGTCCCCATACGGAAGGGG„ 2114,NM_012334„20,4852,CCATACGGAAGGGGCAGGAG„ 2115,NM_012334„20,4846,GGAAGGGGCAGGAGCGGGGA„

2116,NM_012334„20,4840,GGCAGGAGCGGGGAGTGCAA„ 2117,NM_012334„20,4834,AGCGGGGAGTGCAAGGGGTG„ 2118,NM_012334„20,4828,GAGTGCAAGGGGTGATGGGT„ 2119,NM_012334„20,4822,AAGGGGTGATGGGTGTATCG„ 2120,NM_012334„20,4816,TGATGGGTGTATCGAAGGAT„

2121 ,NM_012334„20,4810,GTGTATCGAAGGATCGGGTT„ 2122,NM_012334„20,4804,CGAAGGATCGGGTTCCGCTT„ 2123,NM_012334„20,4798,ATCGGGTTCCGCTTGTAAAT„ 2124,NM_012334„20,4792,TTCCGCTTGTAAATCTGTTC„ 2125,NM_012334„20,4786,TTGTAAATCTGTTCCACCAC„

2126.NM 012334„20,4780,ATCTGTTCCACCACATCCGA„ 2127,NMl012334„20,4774,TCCACCACATCCGAGTTCAG„ 2128,NM_012334„20,4768,ACATCCGAGTTCAGGCAGTT„ 2129,NM_012334„20,4762,GAGTTCAGGCAGTTCTCCTT„ 2130,NM_012334„20,4756,AGGCAGTTCTCCTTGATATC„

2131 ,NM_012334„20,4750,TTCTCCTTGATATCTTGAAT„ 2132,NM_012334„20,4744,TTGATATCTTGAATCAGCTG„ 2133,NM_012334„20,4738,TCTTGAATCAGCTGCTGGGT„ 2134,NM_012334„20,4732,ATCAGCTGCTGGGTGGGGGT„ 2135,NM_012334„20,4726,TGCTGGGTGGGGGTGTCGAT„

2136,NM_012334„20,4720,GTGGGGGTGTCGATCGGGGC„ 2137,NM_012334„20,4714,GTGTCGATCGGGGCCTTGGT„ 2138,NM_012334„20,4708,ATCGGGGCCTTGGTGTCAGT„ 2139,NM_012334„20,4702,GCCTTGGTGTCAGTCACGTT„ 2140,NM_012334„20,4696,GTGTCAGTCACGTTTTGAAT„

2141 ,NM_012334„20,4690,GTCACGTTTTGAATGGCACT„ 2142,NM_012334„20,4684,TTTTGAATGGCACTGGACCA„ 2143,NM_012334„20,4678,ATGGCACTGGACCACCGGGT„ 2144,NM_012334„20,4672,CTGGACCACCGGGTGGCCTC„ 2145,NM_012334„20,4666,CACCGGGTGGCCTCGTTGAG„

2146,NM_012334„20,4660,GTGGCCTCGTTGAGCAGCTT„ 2147,NM_012334„20,4654_ITCGTTGAGCAGCTTGGTGTA„ 2148,NM_012334„20,4648,AGCAGCTTGGTGTAGAGCCG„ 2149.NM 012334„20_J4642,TTGGTGTAGAGCCGGTAACA„ 2150,NM~012334„20,4636,TAGAGCCGGTAACAGTGCTT„ 2151 ,NM_012334„20,4630,CGGTAACAGTGCTTGCGCCC„ 2152,NM_012334„20,4624,CAGTGCTTGCGCCCGTACAC„ 2153,NM_012334„20,4618,TTGCGCCCGTACACGGTGAC„ 2154,NM_012334„20,4612,CCGTACACGGTGACGTTCCA„ 2155,NM_012334„20,4606,ACGGTGACGTTCCAGTAGCC„

2156,NM_012334„20,4600,ACGTTCCAGTAGCCTGTCTC„ 2157,NM_012334„20,4594,CAGTAGCCTGTCTCTTTGAA„ 2158,NM_012334„20,4588,CCTGTCTCTTTGAATATCTT„ 2159,NM_012334„20,4582,TCTTTGAATATCTTCTCATC„ 2160,NM_012334„20,4576,AATATCTTCTCATCTGGGGG„

2161 ,NM_012334„20,4570,TTCTCATCTGGGGGGACGAC„ 2162,NM_012334„20,4564,TCTGGGGGGACGACAGAGCA„ 2163,NM_012334„20,4558,GGGACGACAGAGCAGAGGCT„ 2164,NM_012334„20,4552,ACAGAGCAGAGGCTGTTGAG„ 2165,NM_012334„20,4546,CAGAGGCTGTTGAGGACCAG„

2166,NM_012334„20,4540,CTGTTGAGGACCAGGGTCCC„ 2167,NM_012334„20,4534,AGGACCAGGGTCCCCAGTTT„ 2168,NMJ)12334„20,4528,AGGGTCCCCAGTTTGAGCGC„ 2169,NM_012334„20,4₅22,CCCAGTTTGAGCGCGTTCTT„ 2170,NM_012334„20,4516,TTGAGCGCGTTCTTCTCTGA„

2171,NM_012334„20,4510,GCGTTCTTCTCTGAACTCTT„ 2172,NM_012334„20,4504,TTCTCTGAACTCTTGTAGTA„ 2173,NM_012334„20,4498,GAACTCTTGTAGTAATCCAG„ 2174,NM_012334„20,4492,TTGTAGTAATCCAGGGAATT„ 2175,NM_012334„20,4486,TAATCCAGGGAATTGTGGGT„

2176,NM_012334„20,4480,AGGGAATTGTGGGTGAGTAC„ 2177,NM_012334„20,4474,TTGTGGGTGAGTACAAACCA„ 2178,NM_012334„20,4468,GTGAGTACAAACCACCGTTT„ 2179,NM_012334„20,4462,ACAAACCACCGTTTCTTCAG„ 2180,NM_012334„20,4456,CACCGTTTCTTCAGTTTCAG„

2181,NM_012334„20,4450,TTCTTCAGTTTCAGTGAAGA„ 2182₎NM_012334„20,4444,AGTTTCAGTGAAGACATCTT„ 2183,NM_012334„20,4438,AGTGAAGACATCTTCGGACT„ 2184,NM_012334„20,4432,GACATCTTCGGACTGTTCTT„ 2185,NM_012334„20,4426,TTCGGACTGTTCTTCACCTC„

2186,NM_012334„20,4420,CTGTTCTTCACCTCTTTGTG„ 2187,NM_012334„20,4414,TTCACCTCTTTGTGCAACCA„ 2188,NM_012334„20,4408,TCTTTGTGCAACCATCCTCT„ 2189,NM_012334„20,4402,TGCAACCATCCTCTCACGAT„ 2190,NM_012334„20,4396,CATCCTCTCACGATGAATTC„

2191 ,NM_012334„20,4390,CTCACGATGAATTCCTGGCC„ 2192,NM_012334„20,4384,ATGAATTCCTGGCCCTCCAC„ 2193,NM_012334„20,4378,TCCTGGCCCTCCACTCTGGT„ 2194,NM 012334„20,4372,CCCTCCACTCTGGTGTCCCC„ 2195,NM^_012334„20,4366,ACTCTGGTGTCCCCTTTGGA„

2196,NM 012334„20,4360,GTGTCCCCTTTGGACCTCTG„ 2197,NM_012334„20,4354,CCTTTGGACCTCTGCAGCAG„ 2198,NM_012334„20,4348,GACCTCTGCAGCAGGGTTAT„ 2199,NM_012334„20,4342,TGCAGCAGGGTTATCCAGTG„ 2200,NM_012334„20,4336,AGGGTTATCCAGTGGTGCAT„

2201 ,NM_012334„20,4330,ATCCAGTGGTGCATCTCCTC„ 2202,NM_012334„20,4324,TGGTGCATCTCCTCCGGCGT„ 2203,NM_012334„20,4318,ATCTCCTCCGGCGTGTCGGC„ 2204,NM_012334„20,4312,TCCGGCGTGTCGGCGTTGCA„ 2205,NM_012334„20,4306,GTGTCGGCGTTGCAGTGCAG„

2206.NM 012334„20,4300,GCGTTGCAGTGCAGCACCCG„ 2207,NM^_012334„20,4294,CAGTGCAGCACCCGGTTGGC„ 2208,NM )12334„20,4288,AGCACCCGGTTGGCCGTGAT„ 2209,NM_012334„20,4282,CGGTTGGCCGTGATGATCAC„ 2210,NM_012334„20,4276,GCCGTGATGATCACAAACGA„

2211 ,NM_012334„20,4270,ATGATCACAAACGAGTTGGG„ 2212,NM 012334„20,4264,ACAAACGAGTTGGGTCTATC„ 2213,NM 012334„20,42₅8,GAGTTGGGTCTATCAGGGCT„ 2214,NM_012334„20,4252,GGTCTATCAGGGCTGTCAGA„ 2215.NM 012334„20,4246,TCAGGGCTGTCAGAGGCACA„

2216,NM^_012334„20,4240,CTGTCAGAGGCACACACAGA„ 2217,NM ) 12334„20,4234,GAGGCACACACAGAATCAAT„ 2218,NM_012334„20,4228,CACACAGAATCAATCAGCCC„ 2219,NM 012334„20,4222,GAATCAATCAGCCCCACATC„ 2220,NM )12334„20,421₆,ATCAGCCCCACATCCAAGGT„

2221 ,NM_012334„20,4210,CCCACATCCAAGGTGCCCAC„ 2222_JNM_012334„20,4204,TCCAAGGTGCCCACAGCATT„ 2223,NM_012334„20,4198,GTGCCCACAGCATTCTGTGG„ 2224,NM_012334„20,4192,ACAGCATTCTGTGGGTTTGC„ 2225,NM_012334„20,4186,TTCTGTGGGTTTGCCTGCTC„ 2226,NM_012334„20,4180,GGGTTTGCCTGCTCATCATG„

2227,NM_012334„20,4174,GCCTGCTCATCATGCATCTC„

2228,NM_012334„20,4168,TCATCATGCATCTCCTGGAT„

2229,NM_012334„20,4162,TGCATCTCCTGGATCTCCTG„ 2230,NM_012334„20,4156,TCCTGGATCTCCTGGTCCGT„

2231,NM_012334„20,4150,ATCTCCTGGTCCGTGGACGC„

2232,NM_012334„20,4144,TGGTCCGTGGACGCGTGGAC„

2233,NM_012334„20,4138,GTGGACGCGTGGACCTGACT„

2234,NM_012334„20,4132,GCGTGGACCTGACTCAGCAC„ 2235,NM_012334₎₎20,4126,ACCTGACTCAGCACGCTGAA„

2236,NM_012334„20,4120,CTCAGCACGCTGAACCACTG„

2237,NM_012334„20,4114,ACGCTGAACCACTGGCTGGC„

2238,NM_012334„20,4108,AACCACTGGCTGGCATCTTC„

2239,NM_012334„20,4102,TGGCTGGCATCTTCTGGGGA„ 2240,NM_012334„20,4096,GCATCTTCTGGGGACTCTGC„

2241.NM 012334„20,4090,TCTGGGGACTCTGCAATCAG„

2242,NM 012334„20,4084,GACTCTGCAATCAGGTGGAA„

2243,NM_012334„20,4078,GCAATCAGGTGGAAAGTCCT„

2244,NM_012334„20,4072,AGGTGGAAAGTCCTATCGGC„ 2245,NM_012334„20,4066,AAAGTCCTATCGGCCATAAT„

2246,NM_012334„20,4060,CTATCGGCCATAATGATGTC„

2247,NM_012334„20,4054,GCCATAATGATGTCGATCCC„

2248,NM_012334„20,4048,ATGATGTCGATCCCATTCTC„

2249,NM_012334„20,4042,TCGATCCCATTCTCCTTGGT„ 2250,NM_012334„20,4036,CCATTCTCCTTGGTGGTGTT„

2251 ,NM_012334„20,4030,TCCTTGGTGGTGTTATCTAT„

2252,NM_012334„20,4024,GTGGTGTTATCTATGATCTC„

2253,NM_012334„20,4018,TTATCTATGATCTCTTTTGC„

2254,NM_012334„20,4012,ATGATCTCTTTTGCCGTTCG„ 2255,NM_012334„20,4006,TCTTTTGCCGTTCGCACTTC„

2256,NM_012334„20,4000,GCCGTTCGCACTTCTACGGT„

2257,NM_012334„20,3994,CGCACTTCTACGGTGCCCTT„

2258,NM_012334„20,3988,TCTACGGTGCCCTTGAGCTT„

2259.NM 012334„20,3982,GTGCCCTTGAGCTTCTCCTC„ 2260,NM~012334„20,3976,TTGAGCTTCTCCTCGCTGTC„

2261 ,NM_012334„20,3970,TTCTCCTCGCTGTCGTTTTC„

2262,NM_012334„20,3964,TCGCTGTCGTTTTCAAAGTA„

2263,NM_012334„20,3958,TCGTTTTCAAAGTACATCAG„

2264.NM 012334„20,3952,TCAAAGTACATCAGCTTGGA„ 2265,NM O 12334„20,3946,TACATCAGCTTGGACTGGCG„

2266,NM_012334„20,3940,AGCTTGGACTGGCGGAGGAC„

2267,NM_012334„20,3934,GACTGGCGGAGGACAAACCA„

2268,NM_012334„20,3928,CGGAGGACAAACCAGCGCTT„

2269,NM_012334„20,3922,ACAAACCAGCGCTTCTTCCA„ 2270,NM_012334„20,3916,CAGCGCTTCTTCCAATTTCT„

2271 ,NM_012334„20,391 O TCTTCCAATTTCTCCTGGA,,

2272,NM_012334„20,3904,CAATTTCTCCTGGACAGCGT„

2273,NM_012334„20,3898,CTCCTGGACAGCGTGGAGGA„

2274,NM_012334„20,3892,GACAGCGTGGAGGAGCCCCC„ 2275,NM 012334„20,3886,GTGGAGGAGCCCCCCCCTTT„

2276,NM~012334„20,3880,GAGCCCCCCCCTTTTTTGTG„

2277,NM_012334„20,3874,CCCCCTTTTTTGTGGAGCCA₁,

2278,NM_012334„20,3868,TTTTTGTGGAGCCAGCCTTG„

2279,NM_012334„20,3862,TGGAGCCAGCCTTGCTTGAG„ 2280,NM_012334₎₎20,3856,CAGCCTTGCTTGAGGGCCTC„

2281 ,NM_012334„20,3850,TGCTTGAGGGCCTCCTGCTT„

2282,NM_012334„20,3844,AGGGCCTCCTGCTTGGAGCG„

2283,NM_012334„20,3838,TCCTGCTTGGAGCGGAACCA„

2284,NM_012334„20,3832,TTGGAGCGGAACCACAAGAA„ 2285,NM_012334„20,3826,CGGAACCACAAGAAGGTTTC„

2286,NM_012334„20,3820,CACAAGAAGGTTTCATCCTT„

2287,NM_012334„20,3814,AAGGTTTCATCCTTGAGGAC„

2288,NM_012334„20,3808,TCATCCTTGAGGACGCACCA„

2289,NM_012334„20,3802,TTGAGGACGCACCAGCGGCG„ 2290,NM_012334„20,3796,ACGCACCAGCGGCGTTTCCA„

2291,NM_012334„20,3790,CAGCGGCGTTTCCAAGAGTT„

2292,NM_012334„20,3784,CGTTTCCAAGAGTTCATCAG„

2293,NM_012334„20,3778,CAAGAGTTCATCAGGCCACC„

2294,NM_012334„20,3772,TTCATCAGGCCACCTTTCAT„ 2295,NM_012334„20,3766,AGGCCACCTTTCATGTACAG„

2296,NM_012334„20,3760,CCTTTCATGTACAGAAAGCT„

2297,NM_012334„20,3754,ATGTACAGAAAGCTGTGGAA„

2298,NM_012334„20,3748,AGAAAGCTGTGGAAATACGG„

2299,NM_012334„20,3742,CTGTGGAAATACGGCAGAGT„ 2300,NM_012334„20_;3736,AAATACGGCAGAGTGACACA„ 2301,NM_012334„20,3730,GGCAGAGTGACACAGCTGTA„

2302,NM_012334„20,3724,GTGACACAGCTGTACACAGA„

2303,NM_012334„20,3718,CAGCTGTACACAGAGTCACG„

2304,NM_012334„20,3712,TACACAGAGTCACGCCGGTA„ 2305,NM_012334„20,3706,GAGTCACGCCGGTATGAAAG„

2306,NM_012334„20,3700,CGCCGGTATGAAAGCTCATC„

2307,NM_012334„20,3694,TATGAAAGCTCATCATCTGT„

2308,NM_012334„20,3688,AGCTCATCATCTGTATCAAA„

2309,NM_012334„20,3682,TCATCTGTATCAAACCTGGA„ 2310,NM_012334„20,3676,GTATCAAACCTGGAATCAAA„

2311,NM_012334„20,3670,AACCTGGAATCAAAGTCCTC„

2312,NM_012334„20,3664,GAATCAAAGTCCTCTTCACT„

2313,NM_012334„20,3658,AAGTCCTCTTCACTATCTTC„

2314,NM_012334„20,3652,TCTTCACTATCTTCAAACGA„ 2315,NM_012334„20,3646,CTATCTTCAAACGAGGACTG„

2316,NM_012334„20,3640,TCAAACGAGGACTGCGCCCC„

2317,NM_012334„20,3634,GAGGACTGCGCCCCCTCAGA„

2318,NM_012334„20,3628,TGCGCCCCCTCAGAGCTGAA„

2319,NM_012334„20,3622,CCCTCAGAGCTGAACCGGTA„ 2320,NM_012334„20,3616,GAGCTGAACCGGTAGGCACC„

2321 ,NM_012334„20,3610,AACCGGTAGGCACCCGAGCT„

2322,NM_012334„20,3604,TAGGCACCCGAGCTGTTGTA„

2323,NM_012334„20,3598,CCCGAGCTGTTGTAGGTCCC„

2324,NM_012334„20,3592,CTGTTGTAGGTCCCCACAGA„ 2325,NM_012334„20,3586,TAGGTCCCCACAGAGCAGCG„

2326,NM_012334„20,3580,CCCACAGAGCAGCGGTAGTC„

2327,NM_012334„20,3574,GAGCAGCGGTAGTCGGGGGA„

2328,NM_012334„20,3568,CGGTAGTCGGGGGACCACTG„

2329,NM_012334,,20,3562,TCGGGGGACCACTGGCTGCC„ 2330,NM_012334„20,3556,GACCACTGGCTGCCGTAGGA„

2331,NM_012334„20,3550,TGGCTGCCGTAGGAGTTGGA„

2332,NM_012334„20,3544,CCGTAGGAGTTGGAGAAGGT„

2333,NM_012334„20,3538,GAGTTGGAGAAGGTCACGCT„

2334,NM_012334„20,3532,GAGAAGGTCACGCTGCTGCC„ 2335,NM_012334„20,3526,GTCACGCTGCTGCCGGAAGT„

2336,NM_012334„20,3520,CTGCTGCCGGAAGTGATGGC„

2337,NM_012334„20,3514,CCGGAAGTGATGGCACCGTC„

2338,NM_012334„20,3508,GTGATGGCACCGTCCTCATA„

2339,NM_012334„20,3502,GCACCGTCCTCATAGTCATC„ 2340,NM_012334„20,3496,TCCTCATAGTCATCCTGGTC„

2341,NM_012334„20,3490,TAGTCATCCTGGTCGTAGTC„

2342,NM_012334„20,3484,TCCTGGTCGTAGTCGTAGTC„

2343,NM_012334„20,3478,TCGTAGTCGTAGTCGCCGTC„

2344,NM_012334„20,3472,TCGTAGTCGCCGTCTGGGGA„ 2345₎NM_012334„20,3466,TCGCCGTCTGGGGAGGGCAA„

2346,NM_012334„20,3460,TCTGGGGAGGGCAAGTCCCC„

2347,NM_012334„20,3454,GAGGGCAAGTCCCCAGCGTT„

2348,NM_012334„20,3448,AAGTCCCCAGCGTTCTGGGG„

2349_>NM_012334„20,3442,CCAGCGTTCTGGGGCATGCA„ 2350,NM_012334„20,3436,TTCTGGGGCATGCAGTAGGT„

2351,NM_012334„20,3430,GGCATGCAGTAGGTGGACTC„

2352,NM_012334„20,3424,CAGTAGGTGGACTCGCCGCT„

2353,NM_012334„20,3418,GTGGACTCGCCGCTGGAGGA„

2354,NM_012334„20,3412,TCGCCGCTGGAGGAGTTGTG„ 2355,NM_012334„20,3406,CTGGAGGAGTTGTGTAGGCT„

2356,NM_012334„20,3400,GAGTTGTGTAGGCTCCCGGA„

2357,NM_012334„20,3394,TGTAGGCTCCCGGAGTCCTG„

2358,NM_012334„20,3388,CTCCCGGAGTCCTGCACTGA„

2359,NM_012334„20,3382,GAGTCCTGCACTGATGGGGC„ 2360,NM_012334„20,3376,TGCACTGATGGGGCGAGCAG„

2361 ,NM_012334„20,3370,GATGGGGCGAGCAGCACCGT„

2362,NM 012334„20,3364,GCGAGCAGCACCGTGCTGTC„

2363,NM~012334„20,3358,AGCACCGTGCTGTCCGCACT„

2364,NM_012334„20,3352,GTGCTGTCCGCACTGGGGCT„ 2365,NM_012334„20,3346,TCCGCACTGGGGCTGGTGGG„

23₆6,NM_012334„20,3340,CTGGGGCTGGTGGGCACCAC„

2367,NM_012334„20,3334,CTGGTGGGCACCACCGTGTC„

2368,NM 012334„20,3328,GGCACCACCGTGTCGTTCAT„

2369,NM 012334„20,3322,ACCGTGTCGTTCATGTATGG„ 2370,NM_012334„20,3316,TCGTTCATGTATGGGTCCTC„

2371 ,NM_012334„20,3310.ATGTATGGGTCCTCCTCTGA,,

2372,NM_012334„20,3304,GGGTCCTCCTCTGAAGAGTC„

2373,NM_012334„20,3298,TCCTCTGAAGAGTCATCGCT„

2374,NM_012334„20,3292,GAAGAGTCATCGCTGGTCCG„ 2375,NM_012334„20,3286,TCATCGCTGGTCCGGATGCC„ 2376,NM_012334„20,3280,CTGGTCCGGATGCCACTTGT„

2377,NM_012334„20,3274,CGGATGCCACTTGTTCGCTG„

2378,NM_012334„20,3268,CCACTTGTTCGCTGGTCTGA„

2379,NM_012334„20,3262,GTTCGCTGGTCTGAGTGGCC„ 2380,NM_012334„20,3256,TGGTCTGAGTGGCCGTGCTC„

2381,NM_012334„20,3250,GAGTGGCCGTGCTCGCTGGG„

2382,NM_012334„20,3244,CCGTGCTCGCTGGGGTTGGG„

2383,NM_012334„20,3238,TCGCTGGGGTTGGGGGAGTC„

2384,NM_012334„20,3232,GGGTTGGGGGAGTCCTTGAA„ 2385,NM_012334„20,3226,GGGGAGTCCTTGAAGGCGTC„

2386,NM_012334„20,3220,TCCTTGAAGGCGTCGTCGTC„

2387,NM_012334„20,3214,AAGGCGTCGTCGTCGGCTTC„

2388,NM_012334„20,3208,TCGTCGTCGGCTTCGAAGCC„

2389,NM_012334„20,3202,TCGGCTTCGAAGCCCTCATC„ 2390,NM_012334„20,3196,TCGAAGCCCTCATCGACCTC„ 2391 ,NM_012334„20,3190,CCCTCATCGACCTCCTCCTC„

2392,NM_012334„20,3184,TCGACCTCCTCCTCTGGGTA„

2393,NM_012334„20,3178,TCCTCCTCTGGGTAGGGCTG„

2394.NM 012334„20,3172,TCTGGGTAGGGCTGGCTGAA„ 2395,NMlθl2334„20,3166,TAGGGCTGGCTGAAGTTGAA„

2396,NM_012334„20,3160,TGGCTGAAGTTGAAGTTGGG„

2397,NM_012334„20,3154,AAGTTGAAGTTGGGCTTCTC„

2398,NM_012334„20,3148,AAGTTGGGCTTCTCCTCGCA„

2399,NM_012334„20,3142,GGCTTCTCCTCGCATGCGCT„ 2400,NM_012334„20,3136,TCCTCGCATGCGCTCTCAGC„

2401,NM_012334„20,3130,CATGCGCTCTCAGCCAGCTC„

2402,NM_012334„20_>3124,CTCTCAGCCAGCTCGCTGGA„

2403,NM_012334„20,3118,GCCAGCTCGCTGGAAAATTC„

2404.NM 012334„20,3112,TCGCTGGAAAATTCGCTTCC„ 2405.NM ) 12334„20,3106,GAAAATTCGCTTCCCACCGA„

2406,NM_012334„20,31 OO.TCGCTTCCCACCGACAGGGA,,

2407,NM_012334„20,3094,CCCACCGACAGGGACCGCTC„

2408,NM_012334„20,3088,GACAGGGACCGCTCGATATT„

2409,NM_012334„20,3082,GACCGCTCGATATTCCGGAC„ 2410₁NM_012334„20,3076,TCGATATTCCGGACACACTC„

2411 ,NM_012334„20,3070,TTCCGGACACACTCGTCGAT„

2412,NM_012334„20,3064,ACACACTCGTCGATCTCGTC„

2413,NM_012334„20,3058,TCGTCGATCTCGTCGAAATT„

2414_JNM_012334„20,3052,ATCTCGTCGAAATTGAGGGA„ 2415,NM_012334„20,3046,TCGAAATTGAGGGACTCGAG„

2416_JNM_012334„20,3040,TTGAGGGACTCGAGGAACTC„

2417,NM_012334„20,3034,GACTCGAGGAACTCCTGGGC„

2418,NM_012334„20,3028,AGGAACTCCTGGGCCGCCCT„

2419,NM_012334„20,3022,TCCTGGGCCGCCCTGCACGC„ 2420,NM_012334„20,3016,GCCGCCCTGCACGCTTCCTC„

2421 ,NM_012334„20,3010,CTGCACGCTTCCTCCTCCAG„

2422,NM_012334„20,3004,GCTTCCTCCTCCAGCCTGCG„

2423,NM_012334„20,2998,TCCTCCAGCCTGCGGAGCTC„

2424.NM ) 12334„20,2992,AGCCTGCGGAGCTCCTGGTC„ 2425,NM_012334„20_S2986,CGGAGCTCCTGGTCCCGCCG„

2426,NM_012334„20,2980,TCCTGGTCCCGCCGCTCCTG„

2427,NM_012334„20,2974,TCCCGCCGCTCCTGCAGCTT„

2428,NM_012334„20,2968,CGCTCCTGCAGCTTCTGCAG„

2429,NM_012334„20,2962,TGCAGCTTCTGCAGGGAAGC„ 2430,NM_012334„20,2956,TTCTGCAGGGAAGCCTCGGT„

2431 ,NM_012334„20,2950,AGGGAAGCCTCGGTCAGCGA„

2432.NM ) 12334„20,2944,GCCTCGGTCAGCGACAGCTC„

2433,NM_012334„20,2938,GTCAGCGACAGCTCCTGCTG„

2434,NM_012334„20,2932,GACAGCTCCTGCTGCTCCTT„ 2435,NM_012334„20,2926,TCCTGCTGCTCCTTCATGCG„

2436,NM_012334„20,2920,TGCTCCTTCATGCGCTGCAG„

2437,NM_012334„20,2914,TTCATGCGCTGCAGGTCCTC„

2438,NM_012334„20,2908,CGCTGCAGGTCCTCGATTTC„

2439,NM_012334„20,2902,AGGTCCTCGATTTCTTTCTC„ 2440,NM_012334„20,2896,TCGATTTCTTTCTCCAGACG„

2441 ,NM_012334„20₁2890,TCTTTCTCCAGACGGAGGAT„

2442,NM_012334„20,2884,TCCAGACGGAGGATCTCTTC„

2443,NM_012334„20,2878,CGGAGGATCTCTTCCACCTG„

2444,NM_012334„20,2872,ATCTCTTCCACCTGCTTATT„ 2445,NM_012334„20,2866,TCCACCTGCTTATTTTCCTT„

2446,NM_012334„20,2860,TGCTTATTTTCCTTCTGTTT„

2447,NM_012334„20,2854,TTTTCCTTCTGTTTCTCCAG„

2448,NM_012334„20,2848,TTCTGTTTCTCCAGTTCACG„

2449,NM_012334„20₎2842,TTCTCCAGTTCACGGGTCAG„ 2450,NM_012334„20,2836,AGTTCACGGGTCAGTTCAGC„ 2451,NM_012334„20,2830,CGGGTCAGTTCAGCTTCCTT„

24₅2,NM_012334„20,2824,AGTTCAGCTTCCTTCTGGCT„

24₅3,NM_012334„20,2818,GCTTCCTTCTGGCTCTTCTG„

24₅4,NM_012334„20,2812,TTCTGGCTCTTCTGCAAGGC„ 24₅₅,NM_012334„20,2806,CTCTTCTGCAAGGCTTCGAG„

2456,NMJ)12334„20,2800,TGCAAGGCTTCGAGTTCTTG„

24₅7,NM_012334„20,2794,GCTTCGAGTTCTTGCTGCTT„

24₅8,NM_012334„20,2788,AGTTCTTGCTGCTTCCTCGT„

24₅9,NM_012334„20,2782,TGCTGCTTCCTCGTTTCTTC„ 2460,NM_012334„20,2776,TTCCTCGTTTCTTCTTCCTG„

2461 ,N _012334„20,2770,GTTTCTTCTTCCTGCTGGGC„

2462,NM_012334„20,2764,TCTTCCTGCTGGGCGCGGAG„

2463,NM_012334„20,27₅8,TGCTGGGCGCGGAGCTCGGC„

2464,NM_012334„20,27₅2,GCGCGGAGCTCGGCTTCTCT„ 246₅,NM_012334„20,2746,AGCTCGGCTTCTCTTCGCTC„

2466,NM_012334„20,2740,GCTTCTCTTCGCTCTCTCTC„

2467,NM_012334„20,2734,CTTCGCTCTCTCTCTCTTTC„

2468,NM_012334„20,2728,TCTCTCTCTCTTTCTCTTTC„

2469,NM_012334„20₎2722,TCTCTTTCTCTTTCTTCTTC„ 2470,NM_012334„20,2716,TCTCTTTCTTCTTCCTCCCG„

2471,NM_012334„20,2710,TCTTCTTCCTCCCGTTTCTT„

2472,NM_012334„20,2704,TCCTCCCGTTTCTTCTTTTC„

2473,NM_012334„20,2698,CGTTTCTTCTTTTCTTCCTC„

2474,NM_012334„20,2692,TTCTTTTCTTCCTCTTCCTG„ 2475,NM_012334„20,2686,TCTTCCTCTTCCTGTTTCTT„

2476_>NM_012334„20,2680,TCTTCCTGTTTCTTCTTTTC„

2477,NM_012334„20,2674,TGTTTCTTCTTTTCTTCTTG„

2478,NM_012334„20,2668,TTCTTTTCTTCTTGCTCCCT„

2479,NM_012334„20,2662,TCTTCTTGCTCCCTTTTCTC„ 2480,NM_012334„20,2656,TGCTCCCTTTTCTCTGCCAG„

2481,NM_012334„20,2650,CTTTTCTCTGCCAGCAATTG„

2482,NM_012334„20,2644,TCTGCCAGCAATTGTCTGTA„

2483,NM_012334„20,2638,AGCAATTGTCTGTAAACTCT„

2484,NM_012334„20,2632,TGTCTGTAAACTCTCCGAGC„ 2485,NM_012334„20,2626,TAAACTCTCCGAGCAATCTG„

2486,NM_012334„20,2620,CTCCGAGCAATCTGACCTCT„

2487,NM_012334„20,2614,GCAATCTGACCTCTGAGTTG„

2488,NM_012334„20,2608,TGACCTCTGAGTTGCTTCTG„

2489,NM_012334„20,2602,CTGAGTTGCTTCTGGAAAAC„ 2490,NM_012334„20,2596,TGCTTCTGGAAAACTATGGC„

2491 ,NM_012334„20,2590,TGGAAAACTATGGCTGCCTT„

2492,NM_012334„20,2584,ACTATGGCTGCCTTTTTCAG„

2493,NM_012334„20,2578,GCTGCCTTTTTCAGGTGCAA„

2494,NM_012334„20,2572,TTTTTCAGGTGCAAAAATCT„ 2495,NMJ)12334,,20,2566,AGGTGCAAAAATCTCCTCCT„

2496,NM_012334„20,2560,AAAAATCTCCTCCTCAGAAG„

2497,NM_012334„20,2554,CTCCTCCTCAGAAGGAATGC„

2498,NM_012334„20,2548,CTCAGAAGGAATGCTCTGTA„

2499,NM_012334„20,2542₎AGGAATGCTCTGTAATTCTT„ 2500,NMIO12334„20,2536,GCTCTGTAATTCTTCTGTAT„

2501,NM_012334„20,2530,TAATTCTTCTGTATTATCAC„

2502,NM_012334„20,2524,TTCTGTATTATCACCACACA„

2503,NM_012334„20,2518,ATTATCACCACACAATAAAG„

2504,NM_012334„20,2512,ACCACACAATAAAGGACCTT„ 2505,NM_012334„20,2506,CAATAAAGGACCTTTCTGTA„

2506,NM_012334„20,2500,AGGACCTTTCTGTATTGTTT„

2507,NM_012334„20,2494,TTTCTGTATTGTTTTCGTGC„

2508,NM_012334„20,2488,TATTGTTTTCGTGCTAAGAA„

2509,NM_012334„20,2482,TTTCGTGCTAAGAAGCCCAA„ 2510,NM_012334„20,2476,GCTAAGAAGCCCAAGACATG„

2511,NM_012334,_>20,2470,AAGCCCAAGACATGGGCCCG„

2512,NM_012334„20,2464,AAGACATGGGCCCGAATCAC„

2513,NM_012334„20,2458,TGGGCCCGAATCACCATGGC„

2514,N _012334„20,2452,CGAATCACCATGGCCGCGTG„ 2515,NM_012334„20,2446,ACCATGGCCGCGTGGCTCAC„

2516,NM_012334„20,2440,GCCGCGTGGCTCACTTCCTC„

2517,NM_012334„20,2434,TGGCTCACTTCCTCTTCCCT„

2518,NM_012334„20,2428,ACTTCCTCTTCCCTCCGCTT„

2519,NM_012334„20,2422,TCTTCCCTCCGCTTCTCCAG„ 2520,NM_012334„20,2416,CTCCGCTTCTCCAGTTTCTG„

2521 ,NM_012334„20,2410,TTCTCCAGTTTCTGTTCCAA„

2522,NM_012334„20,2404,AGTTTCTGTTCCAAGGATTC„

2523,NM_012334„20,2398,TGTTCCAAGGATTCTCGAAG„

2524,NM_012334„20,2392,AAGGATTCTCGAAGAAAGAC„ 2525,NM_012334„20,2386,TCTCGAAGAAAGACCTTGGT„ 2526,NM_012334„20,2380,AGAAAGACCTTGGTCTTCCC„

2527,NM_012334„20,2374,ACCTTGGTCTTCCCCAGCTG„

2₅28,NM_012334„20,2368,GTCTTCCCCAGCTGCCACTC„

2₅29,NM_012334„20,2362,CCCAGCTGCCACTCGCTGTT„ 2₅30,NM_012334„20,2356,TGCCACTCGCTGTTGGAGGC„

2531,NM_012334„20,2350,TCGCTGTTGGAGGCATCATA„

2532,NM_012334„20,2344,TTGGAGGCATCATAGAGCTG„

2533,NM_012334„20,2338,GCATCATAGAGCTGCAGCAG„

2534.NM 012334„20,2332,TAGAGCTGCAGCAGGCTCGT„ 253₅,NM 012334„2O,2326,TGCAGCAGGCTCGTGCACTT„

2536,NM_012334„20,2320,AGGCTCGTGCACTTCCCTCG„

2537,NM_012334„20,2314,GTGCACTTCCCTCGGACGTC„

2538,NM_012334„20,2308,TTCCCTCGGACGTCCTCAGG„

2539,NM_012334„20,2302,CGGACGTCCTCAGGCAGAGC„ 2540,NM_012334„20,2296,TCCTCAGGCAGAGCCAGATT„

2541,NM_012334„20,2290,GGCAGAGCCAGATTCCTCAT„

2542,NM_012334„20,2284,GCCAGATTCCTCATCAGCAC„

2543,NM_012334„20,2278,TTCCTCATCAGCACTTTATA„

2544,NM_012334„20,2272,ATCAGCACTTTATACCTTTT„ 2545,NM_012334„20,2266,ACTTTATACCTTTTGTAAAA„

2546,NM_012334„20,2260,TACCTTTTGTAAAAGTCCTG„

2547,NM_012334„20,2254,TTGTAAAAGTCCTGAAAGGG„

2548,NM_012334„20,2248,AAGTCCTGAAAGGGTCTTCG„

2549,NM_012334„20,2242,TGAAAGGGTCTTCGGACCGC„ 2550,NM_012334,,20,2236,GGTCTTCGGACCGCATACCC„

2₅₅1 ,NM_012334„20,2230,CGGACCGCATACCCAGCTTT„

2552,NM_012334„20,2224,GCATACCCAGCTTTGCGGAT„

2553,NM_012334„20,2218,CCAGCTTTGCGGATTCTCAC„

2554,NM_012334„20,2212,TTGCGGATTCTCACAGTCTC„ 2555,NM_012334„20,2206,ATTCTCACAGTCTCCAGCAT„

2556,NM_012334„20,2200,ACAGTCTCCAGCATCCCTGA„

2557,NM_012334„20,2194,TCCAGCATCCCTGAGTACCG„

2558,NM_012334„20,2188,ATCCCTGAGTACCGCAGCTG„

2₅₅9,NM_012334„20,2182,GAGTACCGCAGCTGGTTCAG„ 2₅60,NM_012334„20,2176,CGCAGCTGGTTCAGCACAAC„

2₅61 ,NM_012334„20,2170,TGGTTCAGCACAACCGCCTG„

2₅62,NM_012334„20,2164,AGCACAACCGCCTGGTCAAA„

2563,NM_012334„20,2158,ACCGCCTGGTCAAACTGGTC„

2564,NM_012334„20,2152,TGGTCAAACTGGTCTGGCAT„ 2565,NM_012334„20,2146,AACTGGTCTGGCATCTTCTG„

2566,NM_012334„20,2140,TCTGGCATCTTCTGCATGTT„

2567,NM_012334„20,2134,ATCTTCTGCATGTTTGGCTT„

2568,NM_012334„20,2128,TGCATGTTTGGCTTGATACA_J,

2569,NM_012334„20,2122,TTTGGCTTGATACAGCGAAC„ 2570,NM_012334„20,2116,TTGATACAGCGAACAAAGAA„

2571 ,NM_012334„20,2110,CAGCGAACAAAGAAAGGATT„

2572,NM_012334„20,2104,ACAAAGAAAGGATTAGAGGA„

2₅73,NM_012334„20,2098,AAAGGATTAGAGGAGCTTAG„

2₅74,NM_012334„20,2092₎TTAGAGGAGCTTAGCGTTGC„ 2₅75,NM_012334„20,2086,GAGCTTAGCGTTGCCATTAA„

2576,NM_012334„20,2080,AGCGTTGCCATTAAGGAATG„

2577,NM_012334„20,2074,GCCATTAAGGAATGCAGTGA„

2578,NM_012334„20,2068,AAGGAATGCAGTGAGTCCTT„

2579,NM_012334„20,2062,TGCAGTGAGTCCTTGAACTG„ 2580,NM_012334„20,2056,GAGTCCTTGAACTGTGAGCT„

2581,NM_012334„20,2050,TTGAACTGTGAGCTGACTGT„

2582,NM_012334„20,2044,TGTGAGCTGACTGTAGGCCG„

2583,NM_012334„20,2038,CTGACTGTAGGCCGCCGATG„

2584,NM 012334„20,2032,GTAGGCCGCCGATGTTTGCT„ 2₅85,NM~012334„20,2026,CGCCGATGTTTGCTTCCACA„

2586,NM_012334„20,2020,TGTTTGCTTCCACATTTCAA„

2587,NM_012334„20,2014,CTTCCACATTTCAAGGTATC„

2588,NM_012334„20,2008,CATTTCAAGGTATCCTGGTT„

2589,NM_012334„20,2002,AAGGTATCCTGGTTGTTGCG„ 2590,NM_012334„20, 1996,TCCTGGTTGTTGCGGCTTGA„

2591 ,NM_012334„20, 1990,TTGTTGCGGCTTGAAACATG„

2592,NM_012334„20, 1984,CGGCTTGAAACATGTTCAAA„

2593,NM_012334„20,1978,GAAACATGTTCAAAAAGATC„

2594,NM_012334„20,1972,TGTTCAAAAAGATCGTAGAT„ 2595,NM_012334„20,1966,AAAAGATCGTAGATAAAGTC„

2596,NM_012334„20,1960,TCGTAGATAAAGTCAAATCG„

2597,NM_012334„20,1954,ATAAAGTCAAATCGGCTTTC„

2598,NM_012334„20, 1948,TCAAATCGGCTTTCTCTTAG„

2599,NM_012334„20, 1942,CGGCTTTCTCTTAGCAAATT„ 2600,NM_012334„20, 1936,TCTCTTAGCAAATTGAGAAG„ 2601 ,NM_012334„20, 1930,AGCAAATTGAGAAGGTCATC„ 2602,NM_012334„20, 1924,TTGAGAAGGTCATCTCGAAA„ 2603,NM_012334„20,1918,AGGTCATCTCGAAATGTATC„ 2604,NM_012334„20, 1912,TCTCGAAATGTATCTCTGTT„ 2605,NM_012334„20,1906_JAATGTATCTCTGTTCTTCTC„

2606,NM_012334„20, 1900,TCTCTGTTCTTCTCCAAGAT„ 2607,NM_012334„20,1894,TTCTTCTCCAAGATACCTCG„ 2608,NM_012334„20,1888,TCCAAGATACCTCGGACATC„ 2609,NM_012334„20,1882,ATACCTCGGACATCATATTG„ 2610,NM_012334„20,1876,CGGACATCATATTGCACCTC„

2611 ,NM_012334„20, 1870,TCATATTGCACCTCTCCAGC„ 2612,NM_012334„20,1864,TGCACCTCTCCAGCATAGTG„ 2613,NM_012334„20,1858,TCTCCAGCATAGTGCTTCAC„ 2614,NM_012334„20_>1852,GCATAGTGCTTCACTCCAAA„ 2615,NM_012334„20, 1846,TGCTTCACTCCAAAATTGTT„

2616,NM_012334„20,1840,ACTCCAAAATTGTTAACTGC„ 2617,NM_012334„20,1834,AAATTGTTAACTGCAACTCT„ 2618,NM_012334„20, 1828,TTAACTGCAACTCTGGGCTT„ 2619,NM_012334„20, 1822,GCAACTCTGGGCTTCACATA„ 2620,NM_012334„20,1816,CTGGGCTTCACATAAAAGTG„

2621 ,NM_012334„20, 1810,TTCACATAAAAGTGGTTATT„ 2622,NM_012334„20,1804,TAAAAGTGGTTATTCGCATG„ 2623,NM_012334„20,1798,TGGTTATTCGCATGCTGACT„ 2624,NM_012334„20, 1792,TTCGCATGCTGACTGTGTAG„ 2625,NM_012334„20,1786,TGCTGACTGTGTAGCTTCTC„

2626,NM_012334„20,1780,CTGTGTAGCTTCTCCAATAA„ 2627,NM_012334„20,1774,AGCTTCTCCAATAAGGTGCT„ 2628,NM_012334„20,1768,TCCAATAAGGTGCTGTCTGT„ 2629,NM_012334„20,1762,AAGGTGCTGTCTGTGGCTTG„ 2630,NM_012334„20, 1756,CTGTCTGTGGCTTGAGGAAA„

2631,NM_012334„20,1750,GTGGCTTGAGGAAAATGGCT„ 2632,NM_012334„20, 1744.TGAGGAAAATGGCTTTCTTC,, 2633,NM_012334„20,1738,AAATGGCTTTCTTCATTGAT„ 2634,NM_012334„20, 1732,CTTTCTTCATTGATAAGGGC„ 2635,NM_012334„20, 1726,TCATTGATAAGGGCTAGGAG„

2636,NM_012334„20,1720,ATAAGGGCTAGGAGGCCAAG„ 2637,NM_012334„20, 1714,GCTAGGAGGCCAAGTTTCTT„ 2638,NM_012334„20,1708,AGGCCAAGTTTCTTCTCAAT„ 2639,NM_012334„20,1702,AGTTTCTTCTCAATCAAGTC„ 2640,NM_012334„20, 1696,TTCTCAATCAAGTCCAGGCA„

2641 ,NM_012334„20, 1690,ATCAAGTCCAGGCATTCTCC„ 2642,NM_012334„20,1684,TCCAGGCATTCTCCATTGTC„ 2643,NM_012334„20,1678,CATTCTCCATTGTCTATCCA„ 2644,NM_012334„20, 1672,CCATTGTCTATCCAGTCAAT„ 2645,NM_012334„20,1666₁TCTATCCAGTCAATATCTTC„

2646,NM_012334„20, 1660.CAGTCAATATCTTCCCACAC,, 2647,NM_012334„20,1654,ATATCTTCCCACACTAATCC„ 2648,NM_012334„20,1648,TCCCACACTAATCCTTCCCG„ 2649,NM_012334„20, 1642,ACTAATCCTTCCCGGCTATA„ 2650,NM_012334„20,1636,CCTTCCCGGCTATATTCTAG„

2651 ,NM_012334„20, 1630,CGGCTATATTCTAGTTGTTC„ 2652,NM_012334„20, 1624,TATTCTAGTTGTTCTAAAGA„ 2653,NM_012334„20, 1618,AGTTGTTCTAAAGAAAAAAT„ 2654,NM_012334„20, 1612,TCTAAAGAAAAAATATGCTT„ 26₅₅,NM_012334„20,1606,GAAAAAATATGCTTGTTGAA„

26₅6,NM_012334„20, 1600,ATATGCTTGTTGAAGTACTC„ 26₅7,NM_012334„20, 1594,TTGTTGAAGTACTCCTGAAG„ 26₅8,NM_012334„20,1588,AAGTACTCCTGAAGTTTCTC„ 2659,NM_012334„20, 1582,TCCTGAAGTTTCTCGTTTGC„ 2660,NM_012334„20,1₅76,AGTTTCTCGTTTGCATAGTT„

2661 ,NM_012334„20, 1570,TCGTTTGCATAGTTTATATT„ 2662,NM_012334„20, 1564,GCATAGTTTATATTGAACTG„ 2663,NM_012334„20,1558,TTTATATTGAACTGTTCAAA„ 2664,NM_012334„20,1552,TTGAACTGTTCAAAGTGATT„ 2665,NM_012334„20,1546,TGTTCAAAGTGATTAACCTC„

2666,NM 012334„20, 1540,AAGTGATTAACCTCAAAGTT„ 2667,NM 012334„20,1534,TTAACCTCAAAGTTTTCAAA„ 2668,NM_012334„20,1528,TCAAAGTTTTCAAATCCAAA„ 2669,NM_012334„20,1522,TTTTCAAATCCAAAGATGTC„ 2670,NM_012334„20, 1516,AATCCAAAGATGTCGAGGAT„

2671 ,NM_012334„20, 1510.AAGATGTCGAGGATGCCAAT,, 2672,NM_012334„20,1504,TCGAGGATGCCAATAGACTT„ 2673,NM_012334„20,1498,ATGCCAATAGACTTGAAGTC„ 2674,NM_012334„20, 1492.ATAGACTTGAAGTCCTCATT,, 2675,NM_012334„20,1486,TTGAAGTCCTCATTGCCTTT„ 2676,NM_012334„20,1480,TCCTCATTGCCTTTGATCCT„ 2677,NM_012334„20,1474,TTGCCTTTGATCCTGCTGTT„ 2678,NM_012334„20,1468,TTGATCCTGCTGTTGATCTT„ 2679,NM_012334„20, 1462,CTGCTGTTGATCTTCTTGAT„ 2680,NM_012334„20,1456,TTGATCTTCTTGATTACCCA„

2681 ,NM_012334„20, 1450,TTCTTGATTACCCACTCAAA„ 2682,NM_012334„20,1444,ATTACCCACTCAAAGCAGCA„ 2683,NM_012334„20,1438,CACTCAAAGCAGCACGCATA„ 2684,NM_012334„20,1432,AAGCAGCACGCATACAGAGC„ 2685,NM_012334„20,1426,CACGCATACAGAGCCATGGC„

2686,NM_012334„20,1420,TACAGAGCCATGGCCAGGGA„ 2687,NM_012334„20,1414,GCCATGGCCAGGGAGTCCCT„ 2688,NM_012334„20, 1408,GCCAGGGAGTCCCTGCTGTC„ 2689,NM_012334„20, 1402,GAGTCCCTGCTGTCTACTGC„ 2690,NM_012334„20, 1396,CTGCTGTCTACTGCCTGTTG„

2691 ,NM 012334„20, 1390,TCTACTGCCTGTTGAACATT_S, 2692.NM J) 12334„20, 13 S4,GCCTGTTGAACATTGAGAGG„ 2693,NM_012334„20, 1378,TGAACATTGAGAGGCGTGAG„ 2694,NM_012334..20, 1372,TTGAGAGGCGTGAGGATCTC„ 2695,NM_012334„20,1366,GGCGTGAGGATCTCTTCTCC„

2696,NM 012334„20, 1360,AGGATCTCTTCTCCCCTGAG„ 2697.NM ) 12334„20, 1354,TCTTCTCCCCTGAGGAACAT„ 2698,NM_012334„20,1348,CCCCTGAGGAACATTGATCT„ 2699,NM_012334„20, 1342,AGGAACATTGATCTCTGGGT„ 2700,NM_012334„20, 1336,ATTGATCTCTGGGTCAAAGC„

2701,NM_012334„20,1330,CTCTGGGTCAAAGCATCTGT„ 2702,NM_012334„20,1324,GTCAAAGCATCTGTGAGCTG„ 2703,NM_012334„20, 1318,GCATCTGTGAGCTGTGTTGG„ 2704,NM_012334„20,1312,GTGAGCTGTGTTGGGTCCAG„ 2705,NM_012334„20,1306,TGTGTTGGGTCCAGCCCAAG„

2706,NM_012334„20,1300,GGGTCCAGCCCAAGTAACTC„ 2707,NM_012334„20, 1294,AGCCCAAGTAACTCCGCAGA„ 2708,NM_012334„20,1288,AGTAACTCCGCAGATCTGCC„ 2709,NM_012334„20,1282,TCCGCAGATCTGCCCAAAGC„ 2710,NM_012334„20, 1276,GATCTGCCCAAAGCTGTTTT„

2711 ,NM_012334„20, 1270.CCCAAAGCTGTTTTGAAGGA,, 2712,NM_012334„20,1264,GCTGTTTTGAAGGAAACCTG„ 2713,NM_012334₎₎20,1258,TTGAAGGAAACCTGTGCCCC„ 2714,NM_012334„20, 1252,GAAACCTGTGCCCCACCAGC„ 2715,NM_012334„20, 1246,TGTGCCCCACCAGCAGTGAT„

2716,NM_012334„20, 1240,CCACCAGCAGTGATAAATTC„ 2717,NM_012334„20,1234,GCAGTGATAAATTCTATGTT„ 2718,NM_012334„20, 1228,ATAAATTCTATGTTCCCAAG„ 2719,NM_012334„20,1222,TCTATGTTCCCAAGATGCAG„ 2720,NM_012334„20, 1216,TTCCCAAGATGCAGTATACC„

2721,NM_012334„20,1210,AGATGCAGTATACCAGCAAG„ 2722,NM_012334„20,1204,AGTATACCAGCAAGCAGCCT„ 2723,NM_012334„20,1198,CCAGCAAGCAGCCTCGACAC„ 2724,NM_012334„20, 1192.AGCAGCCTCGACACTTCCCG,, 2725,NM_012334„20,1186.CTCGACACTTCCCGAACTTC,,

2726,NM_012334„20, 1180,ACTTCCCGAACTTCCTCCTT„ 2727,NM_012334„20, 1174,CGAACTTCCTCCTTGCTGAA„ 2728,NM_012334„20, 1168,TCCTCCTTGCTGAACTGCAT„ 2729,NM_012334„20, 1162,TTGCTGAACTGCATCACGTC„ 2730,NM_012334„20,1156,AACTGCATCACGTCCATTGC„

2731 ,NM_012334„20, 1150.ATCACGTCCATTGCCGTAAT,, 2732,NM_012334„20,1144,TCCATTGCCGTAATAACTTC„ 2733,NM_012334„20,1138,GCCGTAATAACTTCCCTAAA„ 2734,NM_012334„20, 1132,ATAACTTCCCTAAAGGATTC„ 2735,NM_012334„20,1126,TCCCTAAAGGATTCCTGGTC„

2736,NM_012334„20, 1120,AAGGATTCCTGGTCACTGAT„ 2737,NM_012334„20,1114,TCCTGGTCACTGATTGTCTT,, 2738,NM_012334„20, 1108,TCACTGATTGTCTTGTCTTC„ 2739,NM_012334„20, 1102,ATTGTCTTGTCTTCTACACA„ 2740,NM_012334„20, 1096,TTGTCTTCTACACATCCAGA„

2741 ,NM_012334„20, 1090.TCTACACATCCAGACTGATT,, 2742,NM_012334„20,1084,CATCCAGACTGATTCAAGTA„ 2743,NM_012334„20,1078,GACTGATTCAAGTAGTGGTA„ 2744,NM_012334„20, 1072,TTCAAGTAGTGGTAGTTTTC„ 2745,NM_012334„20,1066,TAGTGGTAGTTTTCTGGCGT„

2746,NM_012334„20,1060,TAGTTTTCTGGCGTAGATAA„ 2747,NM_012334„20,1054,TCTGGCGTAGATAAATAAAA„ 2748,NM_012334„20, 1048,GTAGATAAATAAAATTCTTC„ 2749,NM_012334„20, 1042,AAATAAAATTCTTCTCTTTC„ 2750,NM_012334„20, 1036,AATTCTTCTCTTTCTTCATG„ 2751 ,NM_012334„20, 1030,TCTCTTTCTTCATGTTCCAG„

2752,NM_012334„20, 1024,TCTTCATGTTCCAGCCCTGC„

2753,NM_012334„20, 1018,TGTTCCAGCCCTGCCAGCAG„

2754.NM 012334„20, 1012,AGCCCTGCCAGCAGTGCATA„ 2755.NM 012334„20, 1006,GCCAGCAGTGCATAAAATAT„

2756,NM 012334„20, 1000,AGTGCATAAAATATGTGATA„

2757 MM J) 12334„20,994,TAAAATATGTGATAATTCCT„

2758,NM_012334„20,988,ATGTGATAATTCCTTTCCCC„

2759,NM_012334„20,982,TAATTCCTTTCCCCGGGATT„ 2760,NM_012334„20,976,CTTTCCCCGGGATTTTGCCT„

2761,NM_012334„20,970,CCGGGATTTTGCCTTACTAC„

2762,NM_012334„20,964,TTTTGCCTTACTACTCGGTT„

2763,NM_012334„20,958,CTTACTACTCGGTTTTTTTC„

2764,NM_012334„20,952,ACTCGGTTTTTTTCTAATAA„ 2765,NM_012334„20,946,TTTTTTTCTAATAAATAATC„

2766,NM_012334„20,940,TCTAATAAATAATCTACAAT„

2767,NM_012334„20,934,AAATAATCTACAATTCTCCC„

2768,NM_012334„20,928₎TCTACAATTCTCCCGCCCTG„

2769,NM_012334„20,922,ATTCTCCCGCCCTGAATATT„ 2770,NM_012334„20,916,CCGCCCTGAATATTTCCTTT„

2771,NM_012334„20,910,TGAATATTTCCTTTCTGACA„

2772,NM_012334„20,904,TTTCCTTTCTGACAGATGTT„

2773.NM 012334„20,898,TTCTGACAGATGTTCAGCTG„

2774,NM )12334„20,892,CAGATGTTCAGCTGAACAAA„ 2775,NM_012334„20,886,TTCAGCTGAACAAACTTCCC„

2776,NM_012334„20,880,TGAACAAACTTCCCAAAGCG„

2777,NM_012334„20,874,AACTTCCCAAAGCGACTAGA„

2778,NM_012334„20,868,CCAAAGCGACTAGAGTTGTT„

2779,NM_012334„20,862,CGACTAGAGTTGTTGTTGTA„ 2780,NM_012334„20,856,GAGTTGTTGTTGTACACGGT„

2781 ,NM_012334„20,850,TTGTTGTACACGGTCTTCGC„

27S2,NM_012334„20,844,TACACGGTCTTCGCATTGCC„

2783,NM_012334„20,838,GTCTTCGCATTGCCGAAAGC„

2784,NM_012334„20,832,GCATTGCCGAAAGCTTCCAT„ 2785,NM_012334„20,826,CCGAAAGCTTCCATGATGGG„

2786,NM_012334„20,820,GCTTCCATGATGGGGCTGCT„

2787,NM_012334„20,814,ATGATGGGGCTGCTTTCAAG„

2788,NM_012334„20,808,GGGCTGCTTTCAAGAATAGC„

2789,NM_012334„20,802,CTTTCAAGAATAGCTCGTTC„ 2790,NM_012334„20,796,AGAATAGCTCGTTCAACACA„

2791,NM_012334„20,790,GCTCGTTCAACACAGGATGT„

2792,NM_012334„20,784,TCAACACAGGATGTCTTCTC„

2793,NM_012334„20,778,CAGGATGTCTTCTCCTTTAA„

2794,NM_012334„20,772,GTCTTCTCCTTTAAGGACAA„ 2795,NM_012334„20,766,TCCTTTAAGGACAATTCCAA„

2796,NM_012334„20,760,AAGGACAATTCCAAAGACTG„

2797,NM_012334„20,754,AATTCCAAAGACTGTTGACT„

2798,NM_012334„20,748,AAAGACTGTTGACTGATGAC„

2799,NM_012334„20,742,TGTTGACTGATGACTGACAG„ 2800,NM_012334„20,736,CTGATGACTGACAGAAACTT„

2801,NM_012334„20,730,ACTGACAGAAACTTGAGGAT„

2802,NM_012334„20,724,AGAAACTTGAGGATCAATTT„

2803,NM_012334„20,718,TTGAGGATCAATTTAGTGCT„

2804,NM_012334„20,712,ATCAATTTAGTGCTTTCGGT„ 2805.NMJ) 12334,,20,706,TTAGTGCTTTCGGTTTTACC„

2806,NM_012334„20,700,CTTTCGGTTTTACCTGCCCC„

2807,NM_012334„20,694,GTTTTACCTGCCCCACTTTC„

2808,NM_012334„20,688,CCTGCCCCACTTTCACCACT„

2809,NM_012334„20,682,CCACTTTCACCACTGATGAG„ 2810,NM_012334„20,676,TCACCACTGATGAGGATGCA„

2811 ,NM_012334„20,670,CTGATGAGGATGCACTGGTT„

2812,NM_012334„20,664,AGGATGCACTGGTTGTCGTA„

2813,NM_012334„20,658,CACTGGTTGTCGTAGCGCTT„

2814,NM_012334„20,652,TTGTCGTAGCGCTTCCACAG„ 2815,NMJ) 12334„20,646,TAGCGCTTCCACAGGCAGCG„

2816,NM_012334„20,640,TTCCACAGGCAGCGGTAGCA„

2817,NM_012334„20,634,AGGCAGCGGTAGCACTCGTT„

2818,NM_012334„20,628,CGGTAGCACTCGTTGGCGAT„

2819,NM_012334„20,622,CACTCGTTGGCGATGGCGAA„ 2820,NM_012334„20,616.TTGGCGATGGCGAAGATGTG,,

2821 ,NM_012334„20,610,ATGGCGAAGATGTGCGGGGG„

2822₎NM_012334„20_>604,AAGATGTGCGGGGGCAGCTC„

2823,NM_012334„20,598,TGCGGGGGCAGCTCGCCCAG„

2824,NM_012334„20,592,GGCAGCTCGCCCAGGTGGCG„ 2825,NM_012334„20,586,TCGCCCAGGTGGCGCCGGCT„ 2826,NM_012334„20,580,AGGTGGCGCCGGCTGTACTG„

2827,NM_012334„20,574,CGCCGGCTGTACTGCTCCAT„

2828,NM_012334„20,568,CTGTACTGCTCCATGGTGGC„

2829,NM_012334„20,562,TGCTCCATGGTGGCAGGCTC„ 2830,NM_012334„20,556,ATGGTGGCAGGCTCGTACAG„

2831.NM 012334„20,550,GCAGGCTCGTACAGCCCGGC„

2832,NM~012334„20,544,TCGTACAGCCCGGCGATGGG„

2833,NM_012334„20,538,AGCCCGGCGATGGGCTGGTA„

2834,NM_012334„20,532,GCGATGGGCTGGTAGGGGTT„ 2835,NM_012334„20,526,GGCTGGTAGGGGTTCACGGA„

2836,NM_012334„20,520,TAGGGGTTCACGGAGGCCAG„

2837,NM_012334„20,514,TTCACGGAGGCCAGGATGGA„

2838,NM_012334„20,508,GAGGCCAGGATGGAGCCGAT„

2839,NM_012334„20,502,AGGATGGAGCCGATGTAGGT„ 2840,NM_012334„20,496,GAGCCGATGTAGGTATATAT„

2841 ,NM_012334„20,490,ATGTAGGTATATATTTGATT„

2842,NM_012334„20,484,GTATATATTTGATTTCTCTT„

2843,NM_012334„20,478,ATTTGATTTCTCTTATACCG„

2844,NM_012334„20,472,TTTCTCTTATACCGCTGGAA„ 2845,NM_012334„20,466,TTATACCGCTGGAATAAGTT„

2846,NM_012334„20,460,CGCTGGAATAAGTTATACAT„

2847,NM_012334„20,454,AATAAGTTATACATGATGGA„

2848,NM_012334„20,448,TTATACATGATGGAGCCGCC„

2849,NM_012334„20,442,ATGATGGAGCCGCCATGGAG„ 2850,NM_012334„20,436,GAGCCGCCATGGAGCTCTGT„

2851 ,NM_012334„20,430,CCATGGAGCTCTGTCAAGGA„

2852,NM_012334„20,424,AGCTCTGTCAAGGACGCCAT„

2853,NM_012334„20,418,GTCAAGGACGCCATGTCATC„

2854,NM_012334„20,412,GACGCCATGTCATCCACGCC„ 2855,NM_012334„20,406,ATGTCATCCACGCCCTCCTC„

2856,NM_012334„20,400,TCCACGCCCTCCTCGTTCGT„

2857,NM_012334„20,394,CCCTCCTCGTTCGTGGGGTG„

28₅8,NM_012334„20,388,TCGTTCGTGGGGTGCATAGC„

28₅9,NM_012334„20,382,GTGGGGTGCATAGCAGTCAC„ 2860,NM_012334„20,376,TGCATAGCAGTCACCTTCTG„

2861,NM_012334„20,370,GCAGTCACCTTCTGGTGGGT„

2862,NM_0123^'34„20,364,ACCTTCTGGTGGGTAATTGT„

2863,NM_012334„20,358,TGGTGGGTAATTGTGCTCTG„

2864,NM_012334„20,352,GTAATTGTGCTCTGCTTGTA„ 2865,NM_012334„20,346,GTGCTCTGCTTGTAAGTGAA„

2866,NM 012334„20,340,TGCTTGTAAGTGAATACCTG„

2867,NM_012334„20,334,TAAGTGAATACCTGACCATA„

2868,NM_012334„20,328,AATACCTGACCATAGTCTGT„

2869,NM_012334„20,322,TGACCATAGTCTGTCCGGAA„ 2870,NM_012334„20,316,TAGTCTGTCCGGAAGACGAC„

2871 ,NM_012334„20,310,GTCCGGAAGACGACGATGCC„

2872,NM_012334„20,304,AAGACGACGATGCCTTCTGC„

2873,NM_012334„20,298,ACGATGCCTTCTGCACAGGA„

2874,NM_012334„20,292,CCTTCTGCACAGGAATTTAC„ 2875,NM_012334„20,286,GCACAGGAATTTACAGTACT„

2876,NM_012334„20,280,GAATTTACAGTACTTGGAAA„

2877,NM_012334„20,274,ACAGTACTTGGAAAATGCTG„

2878,NM_012334„20,268,CTTGGAAAATGCTGGCCATT„

2879,NM_012334„20,262,AAATGCTGGCCATTTTCTCT„ 2880,NM_012334„20,256,TGGCCATTTTCTCTCAGCCA„

2881,NM_012334„20,250,TTTTCTCTCAGCCAGACCCG„

2882,NM_012334„20,244,CTCAGCCAGACCCGTGTTCC„

2883,NM_012334„20,238,CAGACCCGTGTTCCCTCGGT„

2884,NM_012334„20,232,CGTGTTCCCTCGGTGAAGAA„ 2885,NM_012334„20,226,CCCTCGGTGAAGAAGTTATC„

2886,NM_012334„20,220,GTGAAGAAGTTATCCATTGT„

2887,NM_012334„20,214,AAGTTATCCATTGTTCCAGC„

2888,NM_012334„20,208,TCCATTGTTCCAGCGCAGTC„

2889,NM_012334„20,202,GTTCCAGCGCAGTCCCGGAC„ 2890,NM_012334„20,196,GCGCAGTCCCGGACTCGCCG„

2891,NM_012334„20,190,TCCCGGACTCGCCGAGTGCC„

2892,NM_012334„20, 184,ACTCGCCGAGTGCCGCTCCG„

2893,NM_012334„20,178,CGAGTGCCGCTCCGACTCGC„

2894,NM_012334„20, 172,CCGCTCCGACTCGCGGAAGT„ 2895,NM_012334„20, 166,CGACTCGCGGAAGTCAGCGC„

2896,NM_012334„20, 160,GCGGAAGTCAGCGCCGCCGC„

2897,NM_012334„20,1₅4,GTCAGCGCCGCCGCGGGTCC„

2898,NM_012334„20,148,GCCGCCGCGGGTCCGGGGAA„

2899,NM_012334„20,142,GCGGGTCCGGGGAAACCATG„ 2900,NM_012334„20,136,CCGGGGAAACCATGCGTGTC„ 2901 ,NM_012334„20, 130,AAACCATGCGTGTCACGGCG„

2902,NM_012334„20,124,TGCGTGTCACGGCGCCACTC„

2903,NM_012334„20, 118,TCACGGCGCCACTCCCGAGG„

2904,NM_012334„20,112,CGCCACTCCCGAGGACGCGC„ 2905,NM_012334„20,106,TCCCGAGGACGCGCGCCCGC„

2906,NM_012334„20,100,GGACGCGCGCCCGCGGGGCT„

2907,NM_012334„20,94,GCGCCCGCGGGGCTCCCCTG„

2908,NM_012334„20,88,GCGGGGCTCCCCTGCTGCCA„

2909,NM_012334„20,82,CTCCCCTGCTGCCATCGCCC„ 2910,NM_012334„20,76,TGCTGCCATCGCCCGGTCCC„

2911,NM_012334„20,70,CATCGCCCGGTCCCTTCTTG„

2912,NM_012334„20,64,CCGGTCCCTTCTTGTCCTTC„

2913₎NM_012334„20,58,CCTTCTTGTCCTTCTCACCT„

2914,NM_012334„20,52,TGTCCTTCTCACCTTTTGTT„ 2915,NM_012334„20,46,TCTCACCTTTTGTTCGCCCA„

2916,NM_012334„20,40,CTTTTGTTCGCCCAAACCCA„

2917,NM_012334„20,34,TTCGCCCAAACCCAAGTCCC„

2918,NM_012334„20,28,CAAACCCAAGTCCCTAACTC„

2919,NM_012334„20,22,CAAGTCCCTAACTCGCCCGT„ 2920,NM_012334„20, 16,CCTAACTCGCCCGTCCCGAC„

2921 ,NM_012334„20, 10,TCGCCCGTCCCGACGGCAGC„

2922,NM_012334„20,4,GTCCCGACGGCAGCCTTTGT„

2923,NM_001743„20,2171,TTTTTTTTTTTTTTTTTTTC„

2924,NM_001743„20,2165,TTTTTTTTTTTTTCAGGTAG„ 2925,NM_001743„20,2159,TTTTTTTCAGGTAGTCACTG„

2926,NM_001743„20,2153 CAGGTAGTCACTGTATTTT,,

2927,NM_001743„20,2147,AGTCACTGTATTTTATTGGA„

2928,NM_001743„20,2141,TGTATTTTATTGGAAAACAT„

2929,NM_001743„20,2135,TTATTGGAAAACATTGATAT„ 2930,NM_001743„20,2129.GAAAACATTGATATATATTT,,

2931 ,NM_001743„20,2123,ATTGATATATATTTTTCTTC„

2932,NM_001743„20,2117,ATATATTTTTCTTCACAGCT„

2933,NM_001743„20,211 l.TTTTCTTCACAGCTTGAACT,,

2934,NM_001743„20,2105,TCACAGCTTGAACTGAACAC„ 2935,NM_001743„20,2099,CTTGAACTGAACACAATATT„

2936,NM_001743„20,2093,CTGAACACAATATTGCCCGG„

2937,NM_001743„20,2087,ACAATATTGCCCGGTTTAAA„

2938,NM_001743„20,2081,TTGCCCGGTTTAAAAAAAAC„

2939,NM_001743„20,2075,GGTTTAAAAAAAACAAAACC„ 2940,NM_001743„20,2069,AAAAAAACAAAACCAAAACA„

2941 ,NM_001743 ,,20,2063 , ACAAAACCAAAACATTCCGA,,

2942,NM_001743„20,2057,CCAAAACATTCCGAAAATGT„

2943,NM_001743„20,2051 ,CATTCCGAAAATGTCCACAG„

2944,NM_001743„20,2045,GAAAATGTCCACAGCCTCAC„ 2945,NM_001743„20,2039,GTCCACAGCCTCACGCCTAC„

2946,NM_001743„20,2033,AGCCTCACGCCTACCTGACC„

2947,NM_001743„20,2027,ACGCCTACCTGACCTTACCC„

2948,NM_001743„20,2021,ACCTGACCTTACCCTCAGCT„

2949,NM_00 i 743„20,2015,CCTTACCCTCAGCTCTTGGC„ 2950,NM_001743„20,2009,CCTCAGCTCTTGGCTGGGTC„

2951,NM_001743„20,2003,CTCTTGGCTGGGTCTCCCAC„

2952,NM_001743„20,1997,GCTGGGTCTCCCACTATGCC„

2953,NM_001743„20, 1991 ,TCTCCCACTATGCCCCATCC„

2954,NM_001743 „20, 19S5,ACTATGCCCCATCCCTCCTT„ 2955,NM_001743„20, 1979,CCCCATCCCTCCTTCCCTCA„

29₅6,NM_001743„20,1973,CCCTCCTTCCCTCAGAGGCT„

2957₎NM_001743„20,1967,TTCCCTCAGAGGCTGGGTGC„

2958,NM_001743„20, 1961 ,CAGAGGCTGGGTGCCAGAGG„

2959,NM_001743 „20, 1955,CTGGGTGCCAGAGGGTGGAT„ 2960,NM_001743„20, 1949,GCCAGAGGGTGGATGAGAAG„

2961,NM_001743„20,1943,GGGTGGATGAGAAGAGATTC„

2962_>NM_001743„20,1937,ATGAGAAGAGATTCTCAAAG„

2963,NM_001743„20,1931,AGAGATTCTCAAAGCTGGGC„

2964,NM_001743 „20, 1925,TCTCAAAGCTGGGCAGGTCC„ 2965_>NM_001743„20,1919,AGCTGGGCAGGTCCCAGGAA„

2966,NM_001743„20, 1913,GCAGGTCCCAGGAAAAGCCA„

2967,NM_001743„20,1907,CCCAGGAAAAGCCACTTGAT„

2968,NM_001743„20,1901,AAAAGCCACTTGATCGACCT„

2969,NM_001743„20, 1895,CACTTGATCGACCTGGGCAG„ 2970,NM_001743„20,1889,ATCGACCTGGGCAGTGAGGG„

2971 ,NM_001743„20, 1883,CTGGGCAGTGAGGGGAAGCA„

2972,NM_001743„20,1877,AGTGAGGGGAAGCAGGGGGT„

2973,NM_001743„20,1871,GGGAAGCAGGGGGTGGGGGG„

2974,NM_001743„20,1865,CAGGGGGTGGGGGGTGGGGT„ 2975,NM_001743„20,1859,GTGGGGGGTGGGGTGGGGAG„ 2976,NM_001743„20,1853,GGTGGGGTGGGGAGGTGGTG„

2977,NM_001743„20,1847,GTGGGGAGGTGGTGGGGGGA„

2978,NM_001743„20,1S41,AGGTGGTGGGGGGAGCCAGA„

2979,NM_001743„20,1835,TGGGGGGAGCCAGATGAAAT„ 2980,NM_001743„20,1829,GAGCCAGATGAAATGAACAG„

2981,NM_001743„20,1823,GATGAAATGAACAGAAAAGG„

2982,NM_001743„20,1817,ATGAACAGAAAAGGGGAAAA„

2983,NM_001743„20,1811,AGAAAAGGGGAAAAAACCCA„

2984,NM_001743„20,1805,GGGGAAAAAACCCAGACGAC„ 2985,NM_001743„20,1799,AAAACCCAGACGACTGAACT„

2986,NM_001743„20,1793,CAGACGACTGAACTGCCCAC„

2987,NM_001743„20, 1787,ACTGAACTGCCCACATTGAC„

2988,NM_001743„20,1781,CTGCCCACATTGACTTACTT„

2989,NM_001743„20,1775,ACATTGACTTACTTGTCCCA„ 2990,NM_001743„20, 1769,ACTTACTTGTCCCAGAGGCG„

2991,NM_001743„20,1763,TTGTCCCAGAGGCGAAAGTC„

2992,NM_001743„20, 1757,CAGAGGCGAAAGTCAGAAGC„

2993,NM_001743„20,1751,CGAAAGTCAGAAGCAAGGGC„

2994,NM_001743,,20,1745,TCAGAAGCAAGGGCACGGAT„ 2995,NM_001743„20,1739,GCAAGGGCACGGATCATGCT„

2996,NM_001743„20,1733,GCACGGATCATGCTCTCCGC„

2997,NM_001743„20,1727,ATCATGCTCTCCGCTGGGGG„

2998,NM_001743„20,1721,CTCTCCGCTGGGGGAGTATG„

2999,NM_001743„20,1715,GCTGGGGGAGTATGGGGGCA„ 3000,NM_001743„20, 1709,GGAGTATGGGGGCAGGCAGG„

3001 ,NM_001743„20, 1703,TGGGGGCAGGCAGGTGGGCG„

3002,NM_001743„20,1697,CAGGCAGGTGGGCGAGGGAA„

3003,NM_001743„20,1691_SGGTGGGCGAGGGAAGAGGCA„

3004,NM_001743„20,1685,CGAGGGAAGAGGCAGGGAAG„ 3005,NM_001743„20, 1679.AAGAGGCAGGGAAGAGGGCA,,

3006,NM_001743„20,1673,CAGGGAAGAGGGCACGGAGC„

3007,NM_001743„20,1667,AGAGGGCACGGAGCACAGAT„

3008,NM_001743„20,1661_JCACGGAGCACAGATGTGAGG„

3009,NM_001743„20,1655,GCACAGATGTGAGGAAGCGG„ 3010,NM_001743 „20, 1649,ATGTGAGGAAGCGGCGCCAA„

3011,NM_001743„20,1643,GGAAGCGGCGCCAAGTCACC„

3012,NM_001743„20, 1637.GGCGCCAAGTCACCACGGAG,,

3013,NM J)01743„20, 1631 ,AAGTCACCACGGAGAAGCGG„

3014,NM_001743„20, 1625,CCACGGAGAAGCGGGAGGTG„ 3015,NM_001743 „20, 1619.AGAAGCGGGAGGTGCTGGCG,,

3016,NM_001743 „20, 1613,GGGAGGTGCTGGCGGACCAG„

3017,NM_001743„20,1607,TGCTGGCGGACCAGGACGCA„

3018,NM_001743 „20, 1601 ,CGGACCAGGACGCAGAGGCT„

3019,NM_001743„20,1595,AGGACGCAGAGGCTGCTGTA„ 3020_>NM_001743„20,1589,CAGAGGCTGCTGTAGCTGCC„

3021,NM_001743„20,1583,CTGCTGTAGCTGCCGTCCCC„

3022,NM_001743„20,1577,TAGCTGCCGTCCCCTGGGCA„

3023,NM~001743„20,1571,CCGTCCCCTGGGCAGCTGGC„

3024,NM_001743„20,1565,CCTGGGCAGCTGGCCGACAA„ 3025,NM_001743„20,1559,CAGCTGGCCGACAAGACTGT„

3026,NM_001743„20, 1553,GCCGACAAGACTGTTTTATT„

3027,NM_001743„20, 1547,AAGACTGTTTTATTGCAGGT„

3028,NM_001743„20,1541,GTTTTATTGCAGGTGCGTTC„

3029,NM_001743„20,1535,TTGCAGGTGCGTTCTCTTGA„ 3030,NM_001743„20,1529,GTGCGTTCTCTTGAGAGCGT„

3031,NM_001743„20,1523,TCTCTTGAGAGCGTGGTGGG„

3032,NM_001743„20,1517,GAGAGCGTGGTGGGGCCCAT„

3033,NM_001743„20,1511,GTGGTGGGGCCCATCTTCCC„

3034,NM_001743 „20, 1505,GGGCCCATCTTCCCTCTCCC„ 3035,NM_001743„20,1499,ATCTTCCCTCTCCCCACCCT„

3036,NM_001743„20,1493,CCTCTCCCCACCCTTTAGCT„

3037,NM_001743„20,1487,CCCACCCTTTAGCTAGCCCA„

3038,NM_001743„20,1481,CTTTAGCTAGCCCAGCATGG„

3039,NM_001743„20,1475,CTAGCCCAGCATGGTTCTGA„ 3040,NM_001743„20,1469,CAGCATGGTTCTGAACAAAA„

3041,NM_001743„20,1463,GGTTCTGAACAAAATGAAAG„

3042,NM_001743„20,1457,GAACAAAATGAAAGTCTTAA„

3043,NM_001743„20, 145 l.AATGAAAGTCTTAAGGGCCA,,

3044,NM_001743„20,1445,AGTCTTAAGGGCCATAGAGG„ 3045,NM_001743„20,1439,AAGGGCCATAGAGGGGAAAG„

3046,NM_001743„20,1433,CATAGAGGGGAAAGAAAAAA„

3047,NM_001743„20,1427,GGGGAAAGAAAAAAAAAGAG„

3048,NM_001743 „20, 1421 ,AGAAAAAAAAAGAGAACCAG„

3049,NM_001743 „20, 1415,AAAAAGAGAACCAGCACATT„ 3050,NM_001743„20,1409,AGAACCAGCACATTACAAAG„ 3051,NM_001743„20,1403,AGCACATTACAAAGCGACCA„

3052,NM_001743„20,1397,TTACAAAGCGACCATCCCCA„

3053,NM_001743„20,1391,AGCGACCATCCCCACATCCA„

3054,NM_001743„20,1385,CATCCCCACATCCATTCCTA„ 3055,NM_001743„20,1379,CACATCCATTCCTAGGACGG„

3056,NM_001743„20,1373,CATTCCTAGGACGGGCCCTC„

3057,NM_001743 „20, 1367,TAGGACGGGCCCTCAGGGCG„

3058,NM_001743„20,1361,GGGCCCTCAGGGCGGTGGGT„

3059,NM_001743„20,1355,TCAGGGCGGTGGGTGCATCG„ 3060,NM_001743 „20, 1349,CGGTGGGTGCATCGTGAGGA„

3061 ,NM_001743 „20, 1343,GTGCATCGTGAGGAGGGAGC„

3062,NM_001743„20,1337,CGTGAGGAGGGAGCGGCATG„

3063,NM_001743„20,1331,GAGGGAGCGGCATGGGATGT„

3064,NM_001743 „20, 1325,GCGGCATGGGATGTTAGCAC„ 3065,NM_001743 „20, 1319,TGGGATGTTAGCACCAGGTA„

3066,NM_001743„20,1313,GTTAGCACCAGGTATTTACA„

3067,NM_001743„20,1307,ACCAGGTATTTACAGAACAG„

3068,NM_001743 „20, 1301 ,TATTTACAGAACAGCTCGAG„

3069,NM_001743„20,1295,CAGAACAGCTCGAGAGCGCT„ 3070_>NM_001743„20,1289,AGCTCGAGAGCGCTTCAGGA„

3071,NM_001743„20,1283,AGAGCGCTTCAGGAACGCGG„

3072,NM_001743„20,1277,CTTCAGGAACGCGGGCAAGT„

3073,NM_001743 „20, 12 1 ,GAACGCGGGCAAGTCCAATC„

3074,NM_001743„20,1265,GGGCAAGTCCAATCTGCAGA„ 3075,NM_001743„20,1259,GTCCAATCTGCAGAGTGGCC„

3076,NM_001743„20,1253,TCTGCAGAGTGGCCAAATGA„

3077,NM_001743 „20, 1247,GAGTGGCCAAATGAGCAGTC„

3078_!NM_001743„20,1241,CCAAATGAGCAGTCCCCACC„

3079,NM_001743„20,1235,GAGCAGTCCCCACCCAGCCA„ 3080,NM_001743„20,1229,TCCCCACCCAGCCAAACCTC„

3081,NM_001743„20,1223,CCCAGCCAAACCTCAGAAAG„

3082,NM_001743„20,I217,CAAACCTCAGAAAGCCAATC„

3083,NM_001743„20,1211,TCAGAAAGCCAATCAGATGG„

3084,NM_001743 „20, 1205,AGCCAATCAGATGGTTTCAG„ 3085,NM_001743„20,1199,TCAGATGGTTTCAGAACAGC„

3086,NM_001743 „20, 1193,GGTTTCAGAACAGCAGCCAG„

3087,NM_001743„20,1187,AGAACAGCAGCCAGTGGGAT„

3088,NM_001743„20,1181,GCAGCCAGTGGGATGTGAGT„

3089,NM_001743 „20, 1175,AGTGGGATGTGAGTGTTGCC„ 3090,NM_001743„20,1169,ATGTGAGTGTTGCCCACTGT„

3091,NM_001743„20,1163,GTGTTGCCCACTGTCAGTCC„

3092,NM_001743 „20, 1157,CCCACTGTCAGTCCCCTTCT„

3093,NM_001743 „20, 1151 ,GTCAGTCCCCTTCTGTGAGT„

3094_>NM_001743„20,1145,CCCCTTCTGTGAGTTGGCCC„ 3095,NM_001743„20,1139,CTGTGAGTTGGCCCCCTCGA„

3096_!NM_001743„20,1133,GTTGGCCCCCTCGACCCCCT„

3097_>NM_001743„20,1127,CCCCTCGACCCCCTCCTGGG„

3098,NM_001743 „20, 1121 ,GACCCCCTCCTGGGCCACAT„

3099,NM_001743„20,1115,CTCCTGGGCCACATCCAGTC„ 3100,NM_001743„20,1109,GGCCACATCCAGTCAACGCC„

3101 ,NM_001743 „20, 1103 , ATCCAGTCAACGCCACAATT,,

3102,NM_001743„20,1097,TCAACGCCACAATTCCTCAA„

3103,NM_001743„20,1091,CCACAATTCCTCAACGCCCC„

3104,NM_001743„20,1085,TTCCTCAACGCCCCCTCAGT„ 3105₁NM_001743„20,1079,AACGCCCCCTCAGTCCTTCT„

3106₁NM_001743„20,1073,CCCTCAGTCCTTCTGGAATG„

3107,NM_001743„20,1067,GTCCTTCTGGAATGCCTCTC„

3108,NM_001743 „20, 1061 ,CTGGAATGCCTCTCTTGGCA„

3109_INM_001743„20,1055,TGCCTCTCTTGGCACCCCTG„ 3110,NM_001743 „20, 1049,TCTTGGCACCCCTGCCCCAA„

3111,NM_001743„20,1043,CACCCCTGCCCCAACAGGCT„

3112,NM_001743„20,1037,TGCCCCAACAGGCTGCTGGG„

3113,NM_001743„20,1031,AACAGGCTGCTGGGATCTGC„

3114,NM_001743„20,1025,CTGCTGGGATCTGCACGTGG„ 3115,NM_001743 „20, 1019,GGATCTGCACGTGGAATCAC„

3116.NM 001743„20,1013,GCACGTGGAATCACAGGGCT„

3117,NM 001743„20,1007,GGAATCACAGGGCTGGTTGC„

3118,NM_001743 „20, 1001 ,ACAGGGCTGGTTGCATGCAA„

3119,NM_001743„20,995_ICTGGTTGCATGCAACGGCAA„ 3120,NM_001743„20,989,GCATGCAACGGCAAAGGGCA„

3121,NM_001743„20_J983,AACGGCAAAGGGCATGCTCT„

3122,NM_001743„20,977,AAAGGGCATGCTCTTCTGCC„

3123,NM_001743„20,971 ,CATGCTCTTCTGCCTGGGGG„

3124,NM_001743„20,965,CTTCTGCCTGGGGGAGGGCC„ 3125,NM_001743„20,959,CCTGGGGGAGGGCCTCTTGT„ 3126,NM_001743„20,953,GGAGGGCCTCTTGTCCCTCC„ 3127,NM_001743„20,947,CCTCTTGTCCCTCCCAGCAG„ 3128,NM_001743„20,941,GTCCCTCCCAGCAGGTCCCG„ 3129,NM_001743„20,935,CCCAGCAGGTCCCGGGACAG„ 3130,NM_001743„20,929,AGGTCCCGGGACAGGGCTGG„

3131,NM_001743„20,923,CGGGACAGGGCTGGCAGCCA„ 3132,NM _001743,,20,917,AGGGCTGGCAGCCACCCCAG„ 3133,NM_001743„20,911,GGCAGCCACCCCAGCACCCA„ 3134,NM_001743„20,905,CACCCCAGCACCCAAAATAA„ 3135,NM_001743„20,899,AGCACCCAAAATAAGATGAC„

3136,NM_001743„20,893,CAAAATAAGATGACAAACAA„ 3137,NM_001743„20,887,AAGATGACAAACAAGAGGAA„ 3138,NM_001743„20,881,ACAAACAAGAGGAAACAAAC„ 3139,NM_001743„20,875,AAGAGGAAACAAACCAAAAT„ 3140,NM_001743„20,869,AAACAAACCAAAATGGAGGA„

3141,NM_001743„20,863,ACCAAAATGGAGGAGAGCCA„ 3142,NMJ)01743,,20,857,ATGGAGGAGAGCCATCCGGG„ 3143,NM_001743„20,851,GAGAGCCATCCGGGCTGGAG„ 3144,NM_001743„20,845,CATCCGGGCTGGAGGAGGGC„ 3145,NM_001743„20,839,GGCTGGAGGAGGGCAGAGGC„

3146,NM_001743„20,833,AGGAGGGCAGAGGCTCCCCA„ 3147,NM_001743„20,827,GCAGAGGCTCCCCAAGGGGA„ 3148,NM_001743„20,821,GCTCCCCAAGGGGATCTGGG„ 3149,NM_001743„20,815,CAAGGGGATCTGGGGAGGGC„ 3150.NM 001743„20,809,GATCTGGGGAGGGCTTCAAC„

3151,NM 001743,,20,803,GGGAGGGCTTCAACTTATGA„ 3152,NM_001743„20,797,GCTTCAACTTATGAATGCAT„ 3153,NM_001743„20,791,ACTTATGAATGCATCAGGCC„ 3154,NM_001743„20,785,GAATGCATCAGGCCTTGGAA„ 3155,NM_001743„20,779,ATCAGGCCTTGGAAGACATG„

3156₎NM_001743„20,773,CCTTGGAAGACATGGATGGA„ 3157,NM_001743„20,767,AAGACATGGATGGAAGAGGC„ 3158,NM_001743„20,761,TGGATGGAAGAGGCGAGGGC„ 3159,NM_001743„20,755,GAAGAGGCGAGGGCAAAAGG„ 3160,NM_001743„20,749,GCGAGGGCAAAAGGAAGAGA„

3161,NM_001743„20,743,GCAAAAGGAAGAGATGAGGG„ 3162,NM_001743„20,737,GGAAGAGATGAGGGGCATGG„ 3163,NM_001743„20,731,GATGAGGGGCATGGAGAGAG„ 3164,NM_001743„20,725,GGGCATGGAGAGAGACTCAG„ 3165,NM_001743„20,719,GGAGAGAGACTCAGGGAAGA„

3166,NM_001743„20,713,AGACTCAGGGAAGAAGGAGA„ 3167,NM_001743„20,707,AGGGAAGAAGGAGAAAGAGC„ 3168,NM_001743„20,701,GAAGGAGAAAGAGCAATCAT„ 3169,NM_001743„20,695,GAAAGAGCAATCATGCAGCT„ 3170,NM_001743„20,689,GCAATCATGCAGCTTGGGAC„

3171,NM_001743„20,683,ATGCAGCTTGGGACAAATCT„ 3172,NM_001743„20,677,CTTGGGACAAATCTTTTGTT„ 3173,NM_001743„20,671,ACAAATCTTTTGTTGCTTTA„ 3174,NM_001743„20,665,CTTTTGTTGCTTTATCAGAT„ 3175,NM_001743„20,659,TTGCTTTATCAGATTCTCAG„

3176,NM_001743„20,653,TATCAGATTCTCAGTCAATC„ 3177,NM_001743„20,647,ATTCTCAGTCAATCAATTGG„ 3178,NM_001743„20,641,AGTCAATCAATTGGTGTTTG„ 3179,NM_001743„20,635,TCAATTGGTGTTTGCTAGAA„ 3180,NM_001743„20,629,GGTGTTTGCTAGAACCGGGG„

3181 ,NM_001743„20,623,TGCTAGAACCGGGGTACGCA„ 3182,NM_001743„20,617,AACCGGGGTACGCAGGGGAG„ 3183,NM_001743„20,611 ,GGTACGCAGGGGAGTGTTGA„ 3184,NM_001743„20,605,CAGGGGAGTGTTGAAGAGAG„ 3185,NM_001743„20,599,AGTGTTGAAGAGAGAGTGCG„

3186,NM_001743„20,593,GAAGAGAGAGTGCGCGCGCG„ 3187,NM_001743„20,587,AGAGTGCGCGCGCGAGAAGA„ 318S,NM_001743„20,581,CGCGCGCGAGAAGAGAGAGA„ 3189,NM_001743„20,575,CGAGAAGAGAGAGATCAAGA„ 3190,NM_001743„20,569,GAGAGAGATCAAGAGAACGG„

3191,NM_001743„20,563,GATCAAGAGAACGGGCATCG„ 3192,NM_001743„20,557,GAGAACGGGCATCGCCAGCT„ 3193,NM_001743„20,551,GGGCATCGCCAGCTGCCCGG„ 3194,NM_001743„20,54₅,CGCCAGCTGCCCGGGGGGCC„ 319₅,NM_001743„20,539,CTGCCCGGGGGGCCTTCACT„

3196,NM_001743„20,533,GGGGGGCCTTCACTTTGCAG„ 3197,NM_001743„20,527,CCTTCACTTTGCAGTCATCA„ 3198,NM_001743„20,521,CTTTGCAGTCATCATCTGTA„ 3199,NM_001743„20,515,AGTCATCATCTGTACAAACT„ 3200,NM_001743„20,509,CATCTGTACAAACTCTTCAT„ 3201,NM_001743„20,503,TACAAACTCTTCATAATTGA„ 3202,NM_001743„20,497,CTCTTCATAATTGACCTGGC„ 3203,NM_001743„20,491 ,ATAATTGACCTGGCCATCTC„ 3204,NM_001743„20,485,GACCTGGCCATCTCCATCGA„ 3205,NM_001743„20,479,GCCATCTCCATCGATGTCAG„

3206,NM_001743„20,473,TCCATCGATGTCAGCCTCCC„ 3207,NM_001743„20,467,GATGTCAGCCTCCCTGATCA„ 3208,NM_001743„20,461,AGCCTCCCTGATCATCTCAT„ 3209,NM_001743„20,455,CCTGATCATCTCATCCACCT„ 3210,NM_001743„20,449,CATCTCATCCACCTCCTCAT„

3211,NM_001743„20,443,ATCCACCTCCTCATCGGTCA„ 3212,NM_001743„20,437,CTCCTCATCGGTCAGCTTCT„ 3213,NM_001743„20,431,ATCGGTCAGCTTCTCCCCCA„ 3214,NM_001743„20,425,CAGCTTCTCCCCCAGGTTCG„ 3215,NM_001743„20,419,CTCCCCCAGGTTCGTCATTA„

3216,NM_001743 „20,413 ,CAGGTTCGTCATTACGTGAC„ 3217,NM_001743„20,407,CGTCATTACGTGACGCAGCT„ 3218,NM_001743„20,401 ,TACGTGACGCAGCTCTGCGG„ 3219,NM_001743„20,395,ACGCAGCTCTGCGGCGCTGA„ 3220,NM_001743„20,389,CTCTGCGGCGCTGATGTAGC„

3221,NM_001743„20,383,GGCGCTGATGTAGCCATTCC„ 3222,NM_001743„20,377,GATGTAGCCATTCCCATCCT„ 3223,NM_001743„20,371,GCCATTCCCATCCTTGTCAA„ 3224,NM_001743„20,365,CCCATCCTTGTCAAAGACAC„ 3225,NM_001743„20,3₅9,CTTGTCAAAGACACGGAACG„

3226,NM )01743,,20,353,AAAGACACGGAACGCCTCTC„ 3227,NM_001743„20,347,ACGGAACGCCTCTCGGATCT„ 3228,NM_001743„20,341,CGCCTCTCGGATCTCCTCCT„ 3229,NM_001743„20,33₅,TCGGATCTCCTCCTCACTGT„ 3230,NM_001743„20,329,CTCCTCCTCACTGTCTGTGT„

3231,NM_001743„20,323,CTCACTGTCTGTGTCCTTCA„ 3232,NM_001743„20,317,GTCTGTGTCCTTCATCTTTC„ 3233,NM_001743„20,311,GTCCTTCATCTTTCTGGCCA„ 3234,NM_001743„20,30₅,CATCTTTCTGGCCATCATGG„ 3235,NM_001743„20,299,TCTGGCCATCATGGTCAGGA„

3236,NM_001743„20,293,CATCATGGTCAGGAACTCCG„ 3237,NM_001743„20,287,GGTCAGGAACTCCGGGAAGT„ 3238,NM_001743„20,281,GAACTCCGGGAAGTCAATGG„ 3239,NM_001743„20,275,CGGGAAGTCAATGGTCCCGT„ 3240,NM_001743„20,269,GTCAATGGTCCCGTTCCCAT„

3241.NM 001743„20,263,GGTCCCGTTCCCATCTGCAT„ 3242,NM 001743„20,257,GTTCCCATCTGCATCCACCT„ 3243,NM_001743„20,251,ATCTGCATCCACCTCATTGA„ 3244,NM_001743„20,245,ATCCACCTCATTGATCATAT„ 3245,NM_001743„20,239,CTCATTGATCATATCCTGCA„

3246,NM_001743„20,233,GATCATATCCTGCAGCTCTG„ 3247,NM_001743„20,227,ATCCTGCAGCTCTGCTTCAG„ 3248,NM_001743„20,221,CAGCTCTGCTTCAGTGGGGT„ 3249,NM_001743„20,215,TGCTTCAGTGGGGTTCTGTC„ 3250,NM_001743„20,209,AGTGGGGTTCTGTCCCAGGG„

3251,NM_001743„20,203,GTTCTGTCCCAGGGATCTCA„ 3252,NM_001743„20, 197,TCCCAGGGATCTCATCACTG„ 3253,NM_001743„20, 191 ,GGATCTCATCACTGTCCCCA„ 3254,NM_001743„20, 18₅,CATCACTGTCCCCAACTCCT„ 32₅₅,NM_001743,,20, 179,TGTCCCCAACTCCTTGGTGG,,

3256,NMJ)01743,,20,173,CAACTCCTTGGTGGTGATAG„ 32₅7,NM_001743„20, 167,CTTGGTGGTGATAGTGCCAT„ 32₅8,NM_001743„20, 161 ,GGTGATAGTGCCATCTCCAT„ 3259,NM_001743 „20, 155,AGTGCCATCTCCATCCTTGT„ 3260,NM_001743„20,149,ATCTCCATCCTTGTCAAAGA,_;

3261,NM_001743„20,143,ATCCTTGTCAAAGAGGGAGA„ 3262,NM_001743„20,137,GTCAAAGAGGGAGAAGGCCT„ 3263,NM_001743„20,131,GAGGGAGAAGGCCTCCTTGA„ 3264,NM_001743„20, 125,GAAGGCCTCCTTGAACTCTG„ 3265,NM_001743„20, 119,CTCCTTGAACTCTGCAATCT„

3266,NM_001743„20,113,GAACTCTGCAATCTGCTCCT„ 3267,NM_001743„20,107,TGCAATCTGCTCCTCAGTCA„ 3268,NM_001743„20,101,CTGCTCCTCAGTCAGCTGGT„ 3269,NM_001743„20,95,CTCAGTCAGCTGGTCAGCCA„ 3270,NM_001743„20,89,CAGCTGGTCAGCCATGGCGA„

3271,NM_001743„20,83,GTCAGCCATGGCGAGGCCCG„ 3272,NM_001743„20,77,CATGGCGAGGCCCGGGGTGT„ 3273,NM_001743„20,71,GAGGCCCGGGGTGTCCGGAG„ 3274,NM_001743„20,65,CGGGGTGTCCGGAGCACGGG„ 3275,NM_001743„20,59,GTCCGGAGCACGGGGATCAA„ 3276,NM_001743„20,53,AGCACGGGGATCAAGGTTCC„

3277,NM_001743„20,47,GGGATCAAGGTTCCTCCGGC„

3278,NM_001743„20,41,AAGGTTCCTCCGGCGGCGGC„

3279.NM 001743„20,35,CCTCCGGCGGCGGCAGCAGC„

3280,NM 001743„20,29,GCGGCGGCAGCAGCTGCAGC„

3281,NM_001743„20,23,GCAGCAGCTGCAGCAGTTCC„

3282,NM_001743„20,17,GCTGCAGCAGTTCCAGCTCC„

3283,NM_001743„20,11,GCAGTTCCAGCTCCGCCGCG„

3284.NM 001743„20,5,CCAGCTCCGCCGCGCCCTCG„

(GENBANK ACCESSION NO. AI095013)

TCCTGATTCAATACTTTTATTTTACCCAATAGGAAAGTAATGGCCTCAGTGCTTGAACTCGGCCACAAATTTCTGATAGGTTTGGAGA ACAGAGTGCTCAGTTCTTCCGTAGAAATGGTGGGTGGCTCTGAAAAGAGCCTTTTGTCTTGTAAGTTTACATTTTTAAAGTTCAGCCC TTACTTGCCCTTAGCTTTGTGGTGGCTCTCAGTCTTCTTGGGGAGCAGTACGGCCTGGATGTTAGGCAGAACACCGCCCTGAGCGAT GGTAACTTTACCAAGCAGCTTGTTGAGCTCCTCGTCGTTGCGGATGGCCAGCTGCAAGTGGCGCGGGATGATGCGGGTCTTTTTGTT

GTCGCGGGCTGCGTTGCCCGCCAGCTCCAGGATCTCGGCAGTTAGGTACTCCAGCACCGCCGCCAGGTAAACCGGCGCGCCGGCCC CGACCCGCTCAGCGTAGTTGCCCTTGCGGAGCAAGCGGTGCACTCGTCCTAC (SEQ ID NO: 3285) 3286,AI095013„20,469,GTAGGACGAGTGCACCGCTT„

3287,AI095013„20,463,CGAGTGCACCGCTTGCTCCG„

3288,AI095013„20,457,CACCGCTTGCTCCGCAAGGG„

3289,AI095013„20,451,TTGCTCCGCAAGGGCAACTA„

3290,AI095013,,20,445,CGCAAGGGCAACTACGCTGA„ 3291 ,AI095013„20,439,GGCAACTACGCTGAGCGGGT„

3292,AI095013„20,433,TACGCTGAGCGGGTCGGGGC„

3293,AI095013„20,427,GAGCGGGTCGGGGCCGGCGC„

3294.AI095013„20,421 ,GTCGGGGCCGGCGCGCCGGT„

3295.AI095013„20,415,GCCGGCGCGCCGGTTTACCT„ 3296,AI095013„20,409,GCGCCGGTTTACCTGGCGGC„

3297,AI095013„20,403,GTTTACCTGGCGGCGGTGCT„

3298,AI095013„20,397,CTGGCGGCGGTGCTGGAGTA„

3299,AI095013„20,391,GCGGTGCTGGAGTACCTAAC„

3300,AI095013„20,385,CTGGAGTACCTAACTGCCGA„ 3301 I095013„20,379,TACCTAACTGCCGAGATCCT„

3302,AI095013„20,373,ACTGCCGAGATCCTGGAGCT„

3303,AI095013„20,367,GAGATCCTGGAGCTGGCGGG„

3304.AI095013„20,361 ,CTGGAGCTGGCGGGCAACGC„

3305,AI095013„20,35₅,CTGGCGGGCAACGCAGCCCG„ 3306,AI095013„20,349,GGCAACGCAGCCCGCGACAA„

3307,AI095013„20,343,GCAGCCCGCGACAACAAAAA„

3308,AI095013„20,337,CGCGACAACAAAAAGACCCG„

3309.AI095013„20,331 ,AACAAAAAGACCCGCATCAT„

3310,AI095013„20,325,AAGACCCGCATCATCCCGCG„ 3311 ,AI095013„20,319,CGCATCATCCCGCGCCACTT„

3312,AI095013„20,313,ATCCCGCGCCACTTGCAGCT„

3313.AI095013„20,307,CGCCACTTGCAGCTGGCCAT„

3314.AI095013„20,301 ,TTGCAGCTGGCCATCCGCAA„

3315,AI095013„20,295,CTGGCCATCCGCAACGACGA„ 3316,AI095013„20,289,ATCCGCAACGACGAGGAGCT„

3317.AI095013„20,283,AACGACGAGGAGCTCAACAA„

3318,AI095013„20,277,GAGGAGCTCAACAAGCTGCT„

3319,AI095013„20,271 ,CTCAACAAGCTGCTTGGTAA„

3320,AI095013„20,265,AAGCTGCTTGGTAAAGTTAC„ 3321,AI095013„20,259,CTTGGTAAAGTTACCATCGC„

3322,AI095013„20,253,AAAGTTACCATCGCTCAGGG„

3323,AI095013„20,247,ACCATCGCTCAGGGCGGTGT„

3324,AI095013„20,241,GCTCAGGGCGGTGTTCTGCC„

3325,AI095013„20,235,GGCGGTGTTCTGCCTAACAT„ 3326,AI095013„20,229,GTTCTGCCTAACATCCAGGC„

3327,AI095013„20,223,CCTAACATCCAGGCCGTACT„

3328,AI095013„20,217,ATCCAGGCCGTACTGCTCCC„

3329,AI095013„20,211,GCCGTACTGCTCCCCAAGAA„

3330,AI095013„20,205,CTGCTCCCCAAGAAGACTGA„ 3331 ,AI095013„20, 199,CCCAAGAAGACTGAGAGCCA„

3332,AI095013„20,193,AAGACTGAGAGCCACCACAA„

3333,AI095013„20,187,GAGAGCCACCACAAAGCTAA„

3334,AI095013„20, 181 ,CACCACAAAGCTAAGGGCAA„

3335,AI095013„20,175,AAAGCTAAGGGCAAGTAAGG„ 3336,AI095013„20,I69,AAGGGCAAGTAAGGGCTGAA„

3337,AI095013„20,163,AAGTAAGGGCTGAACTTTAA„

3338,AI09₅013„20,1₅7,GGGCTGAACTTTAAAAATGT„

3339,AI095013„20,151,AACTTTAAAAATGTAAACTT„

3340,AI095013„20,145,AAAAATGTAAACTTACAAGA„ 3341 ,AI095013„20, 139,GTAAACTTACAAGACAAAAG„ 3342,AI095013„20,133,TTACAAGACAAAAGGCTCTT„

3343,AI095013„20,127,GACAAAAGGCTCTTTTCAGA„

3344,AI095013„20, 121 ,AGGCTCTTTTCAGAGCCACC„

3345,AI095013„20,115,TTTTCAGAGCCACCCACCAT„ 3346,AI095013„20,109₎GAGCCACCCACCATTTCTAC„

3347,AI095013„20,103,CCCACCATTTCTACGGAAGA„

3348,AI095013„20,97,ATTTCTACGGAAGAACTGAG„

3349,AI095013„20,91,ACGGAAGAACTGAGCACTCT„

3350,AI095013„20,85,GAACTGAGCACTCTGTTCTC„ 3351,AI09₅013 ,,20,79, AGCACTCTGTTCTCCAAACC,,

33₅2,AI095013„20,73,CTGTTCTCCAAACCTATCAG„

3353,AI095013„20,67,TCCAAACCTATCAGAAATTT„

3354,AI095013„20,61,CCTATCAGAAATTTGTGGCC„

3355,AI095013„20,₅₅,AGAAATTTGTGGCCGAGTTC„ 3356,AI095013„20,49,TTGTGGCCGAGTTCAAGCAC„

3357,AI095013„20,43,CCGAGTTCAAGCACTGAGGC„

3358,AI095013„20,37,TCAAGCACTGAGGCCATTAC„

3359,AI095013„20,31,ACTGAGGCCATTACTTTCCT„

3360,AI095013„20,25,GCCATTACTTTCCTATTGGG„ 3361 ,AI095013„20, 19,ACTTTCCTATTGGGTAAAAT„

3362,AI095013„20,13,CTATTGGGTAAAATAAAAGT„

3363,AI095013„20,7,GGTAAAATAAAAGTATTGAA„

3364,AI095013„20, 1 ,ATAAAAGTATTGAATCAGGA„

(GENBANK ACCESSION NO. AI672565) GCGGCCGCTCCAACATCGCTGTGACTGTCTCCAGGGCTTCCAGCTGACCCACTCTCTGGGGGGCGGCACGGGGTCCGGGATGGGCA

CCCTGCTCATCAGCAAGATCCGGGAAGAGTACCCAGACCGCATCATGAACACCTTCAGCGTCATGCCCTCACCCAAGGTGTCAGAC

ACGGTGGTGGAGCCCTACAACGCCACCCTCTCGGTCCACCAGCTGGTGGAAAACACAGATGAAACCTACTCCATTGATAACG

(SEQ ID NO: 3365) 3366,AK72565„20,235,CGTTATCAATGGAGTAGGTT„

3367,AI672565„20,229,CAATGGAGTAGGTTTCATCT„

3368,AI672565„20,223,AGTAGGTTTCATCTGTGTTT„

3369,AI672565„20,217,TTTCATCTGTGTTTTCCACC„

3370,AI672565„20,211 ,CTGTGTTTTCCACCAGCTGG„ 3371 ,AI672565„20,205,TTTCCACCAGCTGGTGGACC„

3372,AI672565„20, 199.CCAGCTGGTGGACCGAGAGG,,

3373,AI672565„20, 193,GGTGGACCGAGAGGGTGGCG„

3374,AI672565„20, 187,CCGAGAGGGTGGCGTTGTAG„

3375,AI67256₅„20, 181,GGGTGGCGTTGTAGGGCTCC„ 3376,AI67256₅„20,17₅,CGTTGTAGGGCTCCACCACC„

3377,AI672565„20, 169,AGGGCTCCACCACCGTGTCT„

3378,AI672565„20,163,CCACCACCGTGTCTGACACC„

3379,AI67256₅„20, 157,CCGTGTCTGACACCTTGGGT„

3380,AI672565„20, 151 ,CTGACACCTTGGGTGAGGGC„ 3381 ,AI672565„20, 145,CCTTGGGTGAGGGCATGACG„

3382,AI672565„20,139,GTGAGGGCATGACGCTGAAG„

3383,AI672565„20,133,GCATGACGCTGAAGGTGTTC„

3384,AI672565„20,127,CGCTGAAGGTGTTCATGATG„

3385,AI672565„20,121,AGGTGTTCATGATGCGGTCT„ 3386,AI672565„20,115,TCATGATGCGGTCTGGGTAC„

3387,AI672565„20,109,TGCGGTCTGGGTACTCTTCC„

3388,AI672565„20,103,CTGGGTACTCTTCCCGGATC„

3389,AI672565„20,97,ACTCTTCCCGGATCTTGCTG„

3390,AI672565„20,91,CCCGGATCTTGCTGATGAGC„ 3391 ,AI672565„20,85,TCTTGCTGATGAGCAGGGTG„

3392,AI672565„20,79,TGATGAGCAGGGTGCCCATC„

3393,AI672₅6₅„20,73,GCAGGGTGCCCATCCCGGAC„

3394,AI672₅65„20,67,TGCCCATCCCGGACCCCGTG„

3395,AI672565„20,61,TCCCGGACCCCGTGCCGCCC„ 3396,AI672565„20,55,ACCCCGTGCCGCCCCCCAGA„

3397,AI672565„20,49,TGCCGCCCCCCAGAGAGTGG„

3398,AI672565„20,43,CCCCCAGAGAGTGGGTCAGC„

3399,AI672565„20,37,GAGAGTGGGTCAGCTGGAAG„

3400,AI672565„20,31 ,GGGTCAGCTGGAAGCCCTGG„ 3401,AI672565„20,25,GCTGGAAGCCCTGGAGACAG„

3402,AI672565„20, 19,AGCCCTGGAGACAGTCACAG„

3403,AI672565„20,13,GGAGACAGTCACAGCGATGT„

3404,AI672565„20,7,AGTCACAGCGATGTTGGAGC„

3405,AI672565„20, 1 ,AGCGATGTTGGAGCGGCCGC„ (GENBANK ACCESSION NO. AI652901)

GGGCCTAGGAGTTTTTTGGCGAGACAGGAGGCTGAACCCCGGAGGCTGCAGCCAGGGAGGAGGCAGTGGGCTTCCTGGGGAGCCC

ATCATAAGCAGGGACTGCTCAAGAAGCGCAGGGAGGGCCGAGGTGGGCTTGCAGCCACCCGCCAGGGCCAAACGTTTGCAGGGGC

TGCCCTGAAAGCCGGCGGTGCTGGCTCAAATGAGCATCTTCCTCGGGTTTATTTTTTTAAATAAATCCTCTCTCACCGCCTTTTGCTC CCCCGACCCTCCCAAATCCCCGCCATTGGGGAGGGCGGCTAGGGCCAAGCCTGCAGCTGCCGCTGGTCGTACTCGGCGATGAGCCT CTTGATGTGGGCCAGCTTGCTGTGCAGGTACTCGCAGCGGTGCTTCTCCTGGCTGTAGTTGGGGTTGGTCTTTTTGATTTTTCGATAT TCCTGCAAAATCTGCCCTCGAGTAGTCTCATACTCCTCGGAGCCCTGGGAGAGCTGCCGGAGCTTGGCGTCNAGCTGGGTGAACCC GCGCGTGATGCGCTCAATGTCGGCGTGCAG (SEQ ID NO: 3406)

3407,AI652901 ,,20,618,CTGCACGCCGACATTGAGCG„ 3408,AI652901„20,612,GCCGACATTGAGCGCATCAC„ 3409.AI652901 ,,20,606, ATTGAGCGCATCACGCGCGG,, 3410,AI652901„20,600,CGCATCACGCGCGGGTTCAC„ 3411 ,AI652901 „20,594,ACGCGCGGGTTCACCCAGCT„

3412,AI652901„20,588,GGGTTCACCCAGCTNGACGC„ 3413,AI652901„20,582,ACCCAGCTNGACGCCAAGCT„ 3414,AI652901„20,576,CTNGACGCCAAGCTCCGGCA„ 3415,AI652901„20,570,GCCAAGCTCCGGCAGCTCTC„ 3416,AI652901„20,564,CTCCGGCAGCTCTCCCAGGG„

3417,AI652901„20,558,CAGCTCTCCCAGGGCTCCGA„ 3418,AI652901 „20,552,TCCCAGGGCTCCGAGGAGTA„ 3419.AI652901 „20,546,GGCTCCGAGGAGTATGAGAC„ 3420.AI652901 „20,540,GAGGAGTATGAGACTACTCG„ 3421.AI652901 „20,534,TATGAGACTACTCGAGGGCA„

3422,AI652901„20,528,ACTACTCGAGGGCAGATTTT„ 3423,AI652901„20,522,CGAGGGCAGATTTTGCAGGA„ 3424.AI652901 ,,20,516,CAGATTTTGCAGGAATATCG„ 3425,AI652901„20,510,TTGCAGGAATATCGAAAAAT„ 3426,AI652901„20,504,GAATATCGAAAAATCAAAAA„

3427,AI652901„20,498,CGAAAAATCAAAAAGACCAA„ 3428.AI652901 „20,492,ATCAAAAAGACCAACCCCAA„ 3429,AI652901„20,486,AAGACCAACCCCAACTACAG„ 3430,AI652901„20,480,AACCCCAACTACAGCCAGGA„ 3431 ,AI652901 „20,474,AACTACAGCCAGGAGAAGCA„

3432,AI652901 „20,468,AGCCAGGAGAAGCACCGCTG„ 3433,AI652901„20,462,GAGAAGCACCGCTGCGAGTA„ 3434.AI652901 „20,456,CACCGCTGCGAGTACCTGCA„ 3435,AI652901„20,450,TGCGAGTACCTGCACAGCAA„ 3436,AI652901„20,444,TACCTGCACAGCAAGCTGGC„

3437,AI652901„20,438,CACAGCAAGCTGGCCCACAT„ 3438,AI652901„20,432,AAGCTGGCCCACATCAAGAG„ 3439.AI652901 „20,426,GCCCACATCAAGAGGCTCAT„ 3440,AI652901 „20,420,ATCAAGAGGCTCATCGCCGA„ 3441,AI652901„20,414,AGGCTCATCGCCGAGTACGA„

3442,AI652901„20,408,ATCGCCGAGTACGACCAGCG„ 3443,AI6₅2901„20,402,GAGTACGACCAGCGGCAGCT„ 3444,AI652901„20,396,GACCAGCGGCAGCTGCAGGC„ 3445,AI652901„20,390,CGGCAGCTGCAGGCTTGGCC„ 3446,AI652901„20,384,CTGCAGGCTTGGCCCTAGCC„

3447,AI652901 „20,378,GCTTGGCCCTAGCCGCCCTC„ 3448.AI652901 „20,372,CCCTAGCCGCCCTCCCCAAT„ 3449,AI652901„20,366,CCGCCCTCCCCAATGGCGGG„ 3450,AI652901„20,360,TCCCCAATGGCGGGGATTTG„ 3451 ,AI652901 „20,354,ATGGCGGGGATTTGGGAGGG„

3452.AI652901 „20,348,GGGATTTGGGAGGGTCGGGG„ 3453,AI652901„20,342,TGGGAGGGTCGGGGGAGCAA„ 3454.AI652901 „20,336,GGTCGGGGGAGCAAAAGGCG„ 3455,AI652901„20,330,GGGAGCAAAAGGCGGTGAGA„ 3456.AI652901 „20,324,AAAAGGCGGTGAGAGAGGAT„

3457.AI652901 „20,318,CGGTGAGAGAGGATTTATTT„ 3458,AI652901„20,312,GAGAGGATTTATTTAAAAAA„ 3459,AI652901 „20,306,ATTTATTTAAAAAAATAAAC„ 3460,AI652901 „20,300,TTAAAAAAATAAACCCGAGG„ 3461.AI652901 „20,294,AAATAAACCCGAGGAAGATG„

3462,AI652901„20,288,ACCCGAGGAAGATGCTCATT„ 3463,AI652901„20,282,GGAAGATGCTCATTTGAGCC„ 3464,AI652901 „20,276,TGCTCATTTGAGCCAGCACC„ 3465,AI652901 „20,270,TTTGAGCCAGCACCGCCGGC„ 3466,AI652901 „20,264,CCAGCACCGCCGGCTTTCAG„

3467,AI652901„20,258,CCGCCGGCTTTCAGGGCAGC„ 3468,AI652901„20,252,GCTTTCAGGGCAGCCCCTGC„ 3469.AI652901 „20,246,AGGGCAGCCCCTGCAAACGT„ 3470.AI652901 „20,240,GCCCCTGCAAACGTTTGGCC„ 3471 ,AI652901 „20,234,GCAAACGTTTGGCCCTGGCG„

3472,AI652901„20,228,GTTTGGCCCTGGCGGGTGGC„ 3473,AI652901 „20,222,CCCTGGCGGGTGGCTGCAAG„ 3474.AI652901 ,,20,216,CGGGTGGCTGCAAGCCCACC„ 3475.AI652901 ,,20,210,GCTGCAAGCCCACCTCGGCC„ 3476.AI652901 „20,204,AGCCCACCTCGGCCCTCCCT„ 3477,AI652901 „20, 198,CCTCGGCCCTCCCTGCGCTT„

3478 K52901 „20, 192,CCCTCCCTGCGCTTCTTGAG„

3479.AI652901„20, 186,CTGCGCTTCTTGAGCAGTCC„

3480,AI652901 „20, 180,TTCTTGAGCAGTCCCTGCTT„ 3481 ,AI652901„20, 174,AGCAGTCCCTGCTTATGATG„

3482,AI652901 „20, 168,CCCTGCTTATGATGGGCTCC„

3483,AI652901 „20, 162/TTATGATGGGCTCCCCAGGA,,

3484.AI652901 „20, 156/TGGGCTCCCCAGGAAGCCCA,,

3485,AI652901 „20, 150,CCCCAGGAAGCCCACTGCCT„ 3486,AI652901„20,144,GAAGCCCACTGCCTCCTCCC„

3487.AI652901 „20, 138,CACTGCCTCCTCCCTGGCTG„

3488,AI652901„20,132,CTCCTCCCTGGCTGCAGCCT„

3489,AI652901„20,126,CCTGGCTGCAGCCTCCGGGG„

3490.AI652901 „20, 120,TGCAGCCTCCGGGGTTCAGC„ 3491,AI652901„20,114,CTCCGGGGTTCAGCCTCCTG„

3492,AI652901„20,108,GGTTCAGCCTCCTGTCTCGC„

3493,AI652901„20,102,GCCTCCTGTCTCGCCAAAAA„

3494,AI6₅2901 „20,96,TGTCTCGCCAAAAAACTCCT„

3495.AI652901 „20,90,GCCAAAAAACTCCTAGGCCC„ 3496.AI652901 „20,84,AAACTCCTAGGCCCTTGGGG„

3497.AI652901 „20,78,CTAGGCCCTTGGGGTGGCGC„

3498,AI652901„20,72,CCTTGGGGTGGCGCGCCTGC„

3499.AI652901 „20,66,GGTGGCGCGCCTGCCTTTTT„

3500,AI652901„20,60,GCGCCTGCCTTTTTTAGTTT„ 3501,AI652901„20,54,GCCTTTTTTAGTTTTATACA„

3502.AI652901 „20,48,TTT AGTTTTATACAAAGACA,,

3503,AI652901 „20,42,TTTATACAAAGACAGCCACT„

3504,AI652901 „20,36,CAAAGACAGCCACTTTTAGC„

3505,AI652901„20,30,CAGCCACTTTTAGCTCCTGC„ 3506,AI652901„20,24,CTTTTAGCTCCTGCTAAAAA„

3507.AI652901 „20, 18,GCTCCTGCTAAAAAAAAAAA„

3508,AI652901„20,12,GCTAAAAAAAAAAAAAAAAA„

3509.AI652901 „20,6,AAAAAAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. AI652764) TTGAACAGGGGAAGTTTAATATAAAGATGAACTCTACTCGGAGCATAGAGTTTAAAAAGAGTTCTACACAACACCCTAGGGATGAG

GAAGAATGCCTCAGGGAAGAAAGCACAGAAAAGGAGGTGCCCTCCCGAGGCTGGGACTGAGACCTCCTCGCTGGAGAAGGTGTGG

GAGGCCCCTGAGGGTGAAGTTCCCCGGGTTGCTCGAGCCAGAGTCTGCACAGTCACAGGGCAAGCAGAAAATTCTTTCGAGAGGGT

GGGCGCTCACAGGGAATCGGGAAGCAGAGCCCACCTGCCTACACCTGAAAGGCCACAGCCAGTGCTGGGACCTCTCTGAGGTCTGC

AGACTCCAGGCAGAGCACTCCTGGCAGCTGTGCAGCAGGAGCAGGTAAATTGTCTCCAAAGGACTAGTAAAGGTGACTGGGTCATC CTCCTGCCCCAGGGACACTGATTAGAGAAAATCCGTCTGTGCTGGCAATACGGCAGTGCTGGACACTCGGAATTCCCTTGAA

(SEQ ID NO: 3510)

3511,AI652764„20,492,TTCAAGGGAATTCCGAGTGT„ 3₅12,AI6₅2764„20,486,GGAATTCCGAGTGTCCAGCA„ 3₅13,AI652764„20,480,CCGAGTGTCCAGCACTGCCG„

3514,AI652764„20,474,GTCCAGCACTGCCGTATTGC„ 3515,AI652764„20,468,CACTGCCGTATTGCCAGCAC„ 3516,AI652764„20,462,CGTATTGCCAGCACAGACGG„ 351 ,AI652764„20,456,GCCAGCACAGACGGATTTTC„ 3518,AI652764„20,450,ACAGACGGATTTTCTCTAAT„

3519,AI652764„20,444,GGATTTTCTCTAATCAGTGT„ 3520,AI652764„20,438,TCTCTAATCAGTGTCCCTGG„ 3521 ,AI652764„20,432 ATCAGTGTCCCTGGGGCAGG,, 3522,AI652764„20,426,GTCCCTGGGGCAGGAGGATG„ 3523,AI652764„20,420,GGGGCAGGAGGATGACCCAG„

3524,AI652764„20,414,GGAGGATGACCCAGTCACCT„ 3525,AI652764„20,408,TGACCCAGTCACCTTTACTA„ 3526,AI652764„20,402,AGTCACCTTTACTAGTCCTT„ 3527,AI652764„20,396,CTTTACTAGTCCTTTGGAGA„ 3528,AI652764„20,390,TAGTCCTTTGGAGACAATTT„

3529,AI652764„20,384,TTTGGAGACAATTTACCTGC„ 3530,AI652764„20,378,GACAATTTACCTGCTCCTGC„ 3531 ,AI652764„20,372,TTACCTGCTCCTGCTGCACA„ 3532,AI6₅2764„20,366,GCTCCTGCTGCACAGCTGCC„ 3533,AI652764„20,360,GCTGCACAGCTGCCAGGAGT„

3534,AI652764„20,354_rCAGCTGCCAGGAGTGCTCTG„ 3535,AI652764„20,348,CCAGGAGTGCTCTGCCTGGA„ 3536,AI652764„20,342,GTGCTCTGCCTGGAGTCTGC„ 3537,AI652764„20,336,TGCCTGGAGTCTGCAGACCT„ 3538,AI652764„20,330,GAGTCTGCAGACCTCAGAGA„

3539,AI652764„20,324,GCAGACCTCAGAGAGGTCCC„ 3540,AI652764„20,318,CTCAGAGAGGTCCCAGCACT„ 3541,AI652764„20,312,GAGGTCCCAGCACTGGCTGT„ 3542,AI652764„20,306,CCAGCACTGGCTGTGGCCTT„ 3543,AI652764„20,300,CTGGCTGTGGCCTTTCAGGT„ (

3544,AI652764„20,294,GTGGCCTTTCAGGTGTAGGC„

3545,AI652764„20,288,TTTCAGGTGTAGGCAGGTGG„

3546,AI652764„20,282,GTGTAGGCAGGTGGGCTCTG„

3547,AI652764„20,276,GCAGGTGGGCTCTGCTTCCC„ 3548,AI652764„20,270,GGGCTCTGCTTCCCGATTCC„

3549,AI652764„20,264,TGCTTCCCGATTCCCTGTGA„

3550,AI652764„20,258,CCGATTCCCTGTGAGCGCCC„

3551 _>AI652764„20,252,CCCTGTGAGCGCCCACCCTC„

3552,AI652764„20,246,GAGCGCCCACCCTCTCGAAA„ 3553,AI652764„20,240,CCACCCTCTCGAAAGAATTT„

3554,AI652764„20,234,TCTCGAAAGAATTTTCTGCT„

3555,AI652764„20,228,AAGAATTTTCTGCTTGCCCT„

3556,AI652764„20,222,TTTCTGCTTGCCCTGTGACT„

3557,AI652764„20,216,CTTGCCCTGTGACTGTGCAG„ 3558,AI652764„20,210,CTGTGACTGTGCAGACTCTG„

3559,AI652764„20,204,CTGTGCAGACTCTGGCTCGA„

3560,AI652764„20,198,AGACTCTGGCTCGAGCAACC„

3561 ,AI652764„20, 192,TGGCTCGAGCAACCCGGGGA„

3562,AI652764„20, 186,GAGCAACCCGGGGAACTTCA„ 3563,AI652764„20,180,CCCGGGGAACTTCACCCTCA„

3564,AI652764,,20,174,GAACTTCACCCTCAGGGGCC„

3565,AI652764„20,168,CACCCTCAGGGGCCTCCCAC„

3566,AI652764„20,162,CAGGGGCCTCCCACACCTTC„

3567,AI652764,,20,156,CCTCCCACACCTTCTCCAGC„ 3568,AI652764„20,150,ACACCTTCTCCAGCGAGGAG„

3569,AI652764„20,144,TCTCCAGCGAGGAGGTCTCA„

3570,AI652764„20,138,GCGAGGAGGTCTCAGTCCCA„

3571,AI652764„20,132,AGGTCTCAGTCCCAGCCTCG„

3572,AI652764„20,126,CAGTCCCAGCCTCGGGAGGG„ 3573,AI652764„20,120,CAGCCTCGGGAGGGCACCTC„

3574,AI652764„20,114,CGGGAGGGCACCTCCTTTTC„

3575,AK52764„20,108,GGCACCTCCTTTTCTGTGCT„

3576,AI652764„20,102,TCCTTTTCTGTGCTTTCTTC„

3577,AI652764„20,96_>TCTGTGCTTTCTTCCCTGAG„ 3578,AI652764„20,90,CTTTCTTCCCTGAGGCATTC„

3579,AI652764„20,84,TCCCTGAGGCATTCTTCCTC„

3580,AI652764„20,78,AGGCATTCTTCCTCATCCCT„

3581,AI652764„20,72,TCTTCCTCATCCCTAGGGTG„

3582,AI652764„20,66,TCATCCCTAGGGTGTTGTGT„ 3583,AI652764„20,60,CTAGGGTGTTGTGTAGAACT„

3584,AI652764„20,54,TGTTGTGTAGAACTCTTTTT„

3585,AI652764„20,48,GTAGAACTCTTTTTAAACTC„

3586,AI652764„20,42,CTCTTTTTAAACTCTATGCT„

3587,AI652764„20,36,TTAAACTCTATGCTCCGAGT„ 3588,AI652764„20,30,TCTATGCTCCGAGTAGAGTT„

3589,AI652764„20,24,CTCCGAGTAGAGTTCATCTT„

3590,AI652764„20, 18,GTAGAGTTCATCTTTATATT„

3591 ,AI652764„20, 12,TTCATCTTTATATTAAACTT„

3592,AI652764„20,6,TTTATATTAAACTTCCCCTG„ _τ (G_τE_τN_τB_τA_ττN_τK_π A_τC_τC_τE_τS_τS_τIO_τN_G^ NO_G. _τ A_cA^489_G0_A87_A)^_GGCT^

TTAGAAACCTAGTCAGAGGACAAGCTTCATACAGTATGTATGTACAGTTGGAACTGTTCAAGTATAGTTTCAGTGTAAAAAGTGCTA CAGTAACAAACCACATTTAAGAAAGAGTTCTTAGTAGAGAAACAATAAGACAAAATACCAAACGTAGTACACAACAAATTTATGTC TCAGCTACATGATCTAAAAGTTAAAGGTCCCATGAGCCCCATCCTGAACTTGGAAAGTGTAGCCTTCAGAGGTAGTTTCTGGTACAA CGTTTTGATCTTCCTCTTCCTCTACAGAGAAATACTTCTCAATTAAGCTTAACGAAGCCTTATACACAGACTCATTTTCATGGTTTTGT

AGAGCTTCAATTTTGTCTAAGCCTCCACATTCTTCAATCCTTATACTAAGTGTCTCCGTTTCACCTAGTTTCTCAGCAGGCTCGAAGA TATTTGAAATGGCATC (SEQ ID O: 3593) 3594,AA489087„20,522,GATGCCATTTCAAATATCTT„

3595,AA489087„20,516,ATTTCAAATATCTTCGAGCC„

3596,AA489087„20,510,AATATCTTCGAGCCTGCTGA„

3597,AA489087„20,504,TTCGAGCCTGCTGAGAAACT„

3598,AA489087„20,498,CCTGCTGAGAAACTAGGTGA„ 3599,AA489087„20,492,GAGAAACTAGGTGAAACGGA„

3600,AA489087„20,486,CTAGGTGAAACGGAGACACT„

3601,AA489087„20,480,GAAACGGAGACACTTAGTAT„

3602,AA489087„20,474,GAGACACTTAGTATAAGGAT„

3603,AA489087„20,468,CTTAGTATAAGGATTGAAGA„ 3604,AA489087„20,462,ATAAGGATTGAAGAATGTGG„

3605,AA489087„20,456,ATTGAAGAATGTGGAGGCTT„

3606,AA489087„20,450,GAATGTGGAGGCTTAGACAA„

3607,AA489087„20,444,GGAGGCTTAGACAAAATTGA„

3608,AA489087„20,438,TTAGACAAAATTGAAGCTCT„ 3609,AA489087„20,432,AAAATTGAAGCTCTACAAAA„ 3610,AA489087„20,426,GAAGCTCTACAAAACCATGA„

3611 ,AA489087„20,420,CTACAAAACCATGAAAATGA„

3612,AA489087„20,414 ACCATGAAAATGAGTCTGT„

3613,AA489087„20,408,GAAAATGAGTCTGTGTATAA„ 3614,AA489087„20,402,GAGTCTGTGTATAAGGCTTC„

3615,AA489087„20,396,GTGTATAAGGCTTCGTTAAG„

3616,AA489087„20,390,AAGGCTTCGTTAAGCTTAAT„

3617,AA489087„20,384,TCGTTAAGCTTAATTGAGAA„

3618,AA489087„20,378,AGCTTAATTGAGAAGTATTT„ 3619,AA489087„20,372,ATTGAGAAGTATTTCTCTGT„

3620,AA489087„20,366,AAGTATTTCTCTGTAGAGGA„

3621,AA489087„20,360,TTCTCTGTAGAGGAAGAGGA„

3622,AA489087„20,354,GTAGAGGAAGAGGAAGATCA„

3623,AA489087„20,348,GAAGAGGAAGATCAAAACGT„ 3624,AA489087„20,342,GAAGATCAAAACGTTGTACC„

3625,AA489087„20,336,CAAAACGTTGTACCAGAAAC„

3626,AA489087„20,330,GTTGTACCAGAAACTACCTC„

3627,AA489087„20,324,CCAGAAACTACCTCTGAAGG„

3628,AA489087„20,318,ACTACCTCTGAAGGCTACAC„ 3629,AA489087„20,312,TCTGAAGGCTACACTTTCCA„

3630,AA489087„20_>306,GGCTACACTTTCCAAGTTCA„

3631 ,AA489087„20,300,ACTTTCCAAGTTCAGGATGG„

3632,AA489087„20,294,CAAGTTCAGGATGGGGCTCA„

3633,AA489087„20,288,CAGGATGGGGCTCATGGGAC„ 3634,AA489087„20,282,GGGGCTCATGGGACCTTTAA„

3635,AA489087„20,276,CATGGGACCTTTAACTTTTA„

3636,AA489087„20,270,ACCTTTAACTTTTAGATCAT„

3637,AA489087„20,264,AACTTTTAGATCATGTAGCT„

3638,AA489087„20,258,TAGATCATGTAGCTGAGACA„ 3639,AA489087„20,252,ATGTAGCTGAGACATAAATT„

3640,AA489087„20,246,CTGAGACATAAATTTGTTGT„

3641,AA489087„20,240,CATAAATTTGTTGTGTACTA„

3642,AA489087„20,234,TTTGTTGTGTACTACGTTTG„

3643,AA489087„20,228,GTGTACTACGTTTGGTATTT„ 3644,AA489087„20,222₎TACGTTTGGTATTTTGTCTT„

3645,AA489087„20,216,TGGTATTTTGTCTTATTGTT„

3646,AA489087„20,210,TTTGTCTTATTGTTTCTCTA„

3647,AA489087„20,204,TTATTGTTTCTCTACTAAGA„

3648,AA489087„20,198,TTTCTCTACTAAGAACTCTT„ 3649,AA489087„20, 192,TACTAAGAACTCTTTCTTAA„

3650,AA489087„20, 186,GAACTCTTTCTTAAATGTGG„

3651 ,AA4S9087„20, 180,TTTCTTAAATGTGGTTTGTT„

3652,AA489087„20,174,AAATGTGGTTTGTTACTGTA„

3653,AA489087„20,168,GGTTTGTTACTGTAGCACTT„ 3654,AA489087„20,162,TTACTGTAGCACTTTTTACA„

3655,AA489087„20,156,TAGCACTTTTTACACTGAAA„

3656,AA489087„20,150,TTTTTACACTGAAACTATAC„

3657,AA489087„20,144,CACTGAAACTATACTTGAAC„

3658,AA489087„20,138,AACTATACTTGAACAGTTCC„ 3659,AA489087„20,132,ACTTGAACAGTTCCAACTGT„

3660,AA489087„20,126,ACAGTTCCAACTGTACATAC„

3661,AA489087„20,120,CCAACTGTACATACATACTG„

3662,AA489087„20,114,GTACATACATACTGTATGAA„

3663,AA489087„20, 108.ACATACTGTATGAAGCTTGT,, 3664,AA489087„20,102,TGTATGAAGCTTGTCCTCTG„

3665,AA489087„20,96,AAGCTTGTCCTCTGACTAGG„

3666,AA489087„20,90,GTCCTCTGACTAGGTTTCTA„

3667,AA489087„20,84,TGACTAGGTTTCTAATTTCT„

3668,AA489087„20,78,GGTTTCTAATTTCTATGTGG„ 3669,AA489087„20,72,TAATTTCTATGTGGAATTTC„

3670,AA489087„20,66,CTATGTGGAATTTCCTATCT„

3671 ,AA489087„20,60,GGAATTTCCTATCTTGCAGC„

3672,AA489087„20,54,TCCTATCTTGCAGCATCCTG„

3673,AA489087„20,48,CTTGCAGCATCCTGTAAATA„ 3674,AA489087„20,42,GCATCCTGTAAATAAACATT„

3675,AA489087„20,36,TGTAAATAAACATTCAAGTC„

3676,AA489087„20,30,TAAACATTCAAGTCCACCCT„

3677,AA489087„20,24,TTCAAGTCCACCCTTTTCTT„

3678,AA489087„20,18,TCCACCCTTTTCTTGACTTC„ 3679,AA489087„20,12,CTTTTCTTGACTTCAAAAAA„

3680,AA489087„20,6,TTGACTTCAAAAAAAAAAAA„

(GENBANK ACCESSION NO. AA281534)

GATTGTATAAATAATTTATTTCTGTTCACAGCATCATATATGCATTATAAAAGGCTATGGAAACAAAAGAGAAGGATGATGAGACA

GAGAATTACAGCAGTAGAAAGGAAAACAGAAACCAGGGCACACAGTTCCAACACCAGAACAGAGAATTTGGGAAGATAATTGCTC TGAAACAGAACT (SEQ ID NO: 3681)

3682.AA281534„20, 164,AGTTCTGTTTCAGAGCAATT„

3683.AA281534„20, 1₅8,GTTTCAGAGCAATTATCTTC„ 3684.AA281₅34„20, 1₅2,GAGCAATTATCTTCCCAAAT„

3685,AA281534„20,146,TTATCTTCCCAAATTCTCTG„

3686,AA281534„20,140,TCCCAAATTCTCTGTTCTGG„

3687,AA281₅34„20, 134, ATTCTCTGTTCTGGTGTTGG,,

3688,AA281₅34„20,128,TGTTCTGGTGTTGGAACTGT„ 3689,AA281₅34„20, 122,GGTGTTGGAACTGTGTGCCC„

3690,AA281534„20,116,GGAACTGTGTGCCCTGGTTT„

3691,AA281534„20,110,GTGTGCCCTGGTTTCTGTTT„

3692,AA281534„20, 104,CCTGGTTTCTGTTTTCCTTT„

3693,AA281534„20>98,TTCTGTTTTCCTTTCTACTG„ 3694,AA281534„20,92,TTTCCTTTCTACTGCTGTAA„

3695,AA281₅34„20,86,TTCTACTGCTGTAATTCTCT„

3696,AA281534„20,80,TGCTGTAATTCTCTGTCTCA„

3697,AA281534„20,74,AATTCTCTGTCTCATCATCC„

3698,AA281534„20,68,CTGTCTCATCATCCTTCTCT„ 3699.AA281534„20,62,CATCATCCTTCTCTTTTGTT„

3700,AA281534„20,56,CCTTCTCTTTTGTTTCCATA„

3701 ,AA281534„20,50,CTTTTGTTTCCATAGCCTTT„

3702,AA281534„20,44,TTTCCATAGCCTTTTATAAT„

3703,AA281534„20,38,TAGCCTTTTATAATGCATAT„ 3704,AA281534„20,32,TTTATAATGCATATATGATG„

3705,AA281₅34„20,26,ATGCATATATGATGCTGTGA„

3706,AA281₅34„20,20,ATATGATGCTGTGAACAGAA„

3707,AA281534„20,14,TGCTGTGAACAGAAATAAAT„

3708,AA281534„20,8,GAACAGAAATAAATTATTTA„ 3709,AA281534„20,2,AAATAAATTATTTATACAAT„

(GENBANK ACCESSION NO. AI038433)

CGTTGTCACCCATCTTTAAGTTTTCAACTCATGGACAATCTTTTGGCGTAAATAGGGGAGAGTTAGAGACTTAAATCCCACACATCA TTTTTTTCCCCAGGGAATAATT (SEQ ID NO: 3710)

3711,AI038433„20,180,AATTATTCCCTGGGGAAAAA„

3712,AI038433„20,174,TCCCTGGGGAAAAAAATGAT„

3713,AI038433„20,168,GGGAAAAAAATGATGTGTGG„ 3714,AI038433„20,162,AAAATGATGTGTGGGATTTA„

3715,AI038433„20,156,ATGTGTGGGATTTAAGTCTC„

3716,AI038433„20, 150,GGGATTTAAGTCTCTAACTC„

3717,AI038433„20,144,TAAGTCTCTAACTCTCCCCT„

3718,AI038433,,20,138,TCTAACTCTCCCCTATTTAC„ 3719,AI038433„20,132,TCTCCCCTATTTACGCCAAA„

3720,AI038433„20,126,CTATTTACGCCAAAAGATTG„

3721,AI038433„20,120,ACGCCAAAAGATTGTCCATG„

3722,AI038433„20,114,AAAGATTGTCCATGAGTTGA„

3723,AI038433„20,108,TGTCCATGAGTTGAAAACTT„ 3724,AI038433„20₎102,TGAGTTGAAAACTTAAAGAT„

3725,AI038433„20,96₎GAAAACTTAAAGATGGGTGA„

3726,AI038433„20,90,TTAAAGATGGGTGACAACGC„

3727,AI038433„20,84,ATGGGTGACAACGCAAGAGA„

3728,AI038433„20,78,GACAACGCAAGAGAGATTAT„ 3729,AI038433„20,72,GCAAGAGAGATTATAGTGTC„

3730,AI038433„20,66,GAGATTATAGTGTCTTCCTT„

3731,AI038433„20,60,ATAGTGTCTTCCTTGTATGC„

3732,AI038433„20,54,TCTTCCTTGTATGCTTGTAA„

3733,AI038433„20,48,TTGTATGCTTGTAAATGTCA„ 3734,AI038433„20,42,GCTTGTAAATGTCAAAAATA„

3735,AI038433„20,36,AAATGTCAAAAATAAAAGTA„

3736,AI038433„20,30,CAAAAATAAAAGTAATTTAA„

3737,AI038433„20,24,TAAAAGTAATTTAAAACTAA„

3738,AI038433„20,18,TAATTTAAAACTAACCCAAA„ 3739,AI038433„20,12,AAAACTAACCCAAACCAAAA„

3740,AI038433„20,6,AACCCAAACCAAAAAAAAAA„

(GENBANK ACCESSION NO. AI122689)

TAAACTATCTTTCAGGGTTTTACAATAATAGTTCTTAGGGTATTACAAAATCAAGTACTCTACGGTACTCTTGGAAGAATTAACAGA AATGAAGCTAGTCAACTTTTTTAAGAAACTGAGCAAAGAACAATTAGCAAATTGAGCAGCCTTTTAACCAGGATAGGTTCAGAGAG

GCTCCAGCAGAGCCACGTAATAGATTTATGGACAGAGAAGCTGGTCAACTTTTGATTCTCAAACCCAGGCTGGCCATCCTGCTTCCA TCCAAAACCTGACAATGCTCATGGAACAATGAATATTAGGGTTGAGAAAATTTATTACCAATATCT (SEQ ID NO: 3741) 3742,AI122689„20,397,AGATATTGGTAATAAATTTT„ 3743,AI122689„20,391,TGGTAATAAATTTTCTCAAC„

3744,AI122689„20,385,TAAATTTTCTCAACCCTAAT„

3745,AI122689„20,379_>TTCTCAACCCTAATATTCAT„

3746,AI122689„20,373_>ACCCTAATATTCATTGTTCC„ 3747,AI122689„20,367,ATATTCATTGTTCCATGAGC„

3748,AI122689„20,361,ATTGTTCCATGAGCATTGTC„

3749,AI122689„20,355,CCATGAGCATTGTCAGGTTT„

3750,AI122689„20,349,GCATTGTCAGGTTTTGGATG„

3751,AI122689„20,343,TCAGGTTTTGGATGGAAGCA„ 3752,AI122689„20,337,TTTGGATGGAAGCAGGATGG„

3753,AI122689„20,331,TGGAAGCAGGATGGCCAGCC„

3754,AI122689„20,325,CAGGATGGCCAGCCTGGGTT„

3755,AI122689„20,319,GGCCAGCCTGGGTTTGAGAA„

3756,AI122689„20,313,CCTGGGTTTGAGAATCAAAA„ 3757,AI122689„20,307,TTTGAGAATCAAAAGTTGAC„

3758,AI122689„20,301,AATCAAAAGTTGACCAGCTT„

3759,AI122689„20,295,AAGTTGACCAGCTTCTCTGT„

3760,AI122689„20,289,ACCAGCTTCTCTGTCCATAA„

3761,AI122689„20,283,TTCTCTGTCCATAAATCTAT„ 3762,AI122689„20,277,GTCCATAAATCTATTACGTG„

3763,AI122689„20,271,AAATCTATTACGTGGCTCTG„

3764,AI122689„20,265,ATTACGTGGCTCTGCTGGAG„

3765,AI122689„20,259,TGGCTCTGCTGGAGCCTCTC„

3766,AI122689„20,253,TGCTGGAGCCTCTCTGAACC„ 3767,AI122689„20,247,AGCCTCTCTGAACCTATCCT„

3768,AI122689„20,241,TCTGAACCTATCCTGGTTAA„

3769,AI122689„20,235,CCTATCCTGGTTAAAAGGCT„

3770,AI122689„20,229,CTGGTTAAAAGGCTGCTCAA„

3771,AI122689„20,223,AAAAGGCTGCTCAATTTGCT„ 3772,AI122689„20,217,CTGCTCAATTTGCTAATTGT„

3773,AH22689„20,211,AATTTGCTAATTGTTCTTTG„

3774,AI122689„20,205,CTAATTGTTCTTTGCTCAGT„

3775,AI122689„20,199,GTTCTTTGCTCAGTTTCTTA„

3776,AI122689„20,193,TGCTCAGTTTCTTAAAAAAG„ 3777,AI122689„20,187,GTTTCTTAAAAAAGTTGACT„

3778,AI122689„20,181,TAAAAAAGTTGACTAGCTTC„

3779,AI122689„20,175,AGTTGACTAGCTTCATTTCT„

3780,AI122689„20,169,CTAGCTTCATTTCTGTTAAT„

3781 ,AI122689„20, 163,TCATTTCTGTTAATTCTTCC„ 3782,AI122689„20,157,CTGTTAATTCTTCCAAGAGT„

3783,AI122689„20, 151 ,ATTCTTCCAAGAGTACCGTA„

3784,AI122689„20,145,CCAAGAGTACCGTAGAGTAC„

3785,AI122689„20,139,GTACCGTAGAGTACTTGATT„

3786,AI122689„20,133,TAGAGTACTTGATTTTGTAA„ 3787,AI122689„20,127,ACTTGATTTTGTAATACCCT„

3788,AI122689„20,121,TTTTGTAATACCCTAAGAAC„

3789,AI122689„20,115,AATACCCTAAGAACTATTAT„

3790,AI122689„20,109,CTAAGAACTATTATTGTAAA„

3791,AI122689„20,103,ACTATTATTGTAAAACCCTG„ 3792,AI122689„20_!97,ATTGTAAAACCCTGAAAGAT„

3793,AI122689„20,91,AAACCCTGAAAGATAGTTTA„

3794,AI122689„20,85,TGAAAGATAGTTTATATTGG„

3795,AI122689„20,79,ATAGTTTATATTGGAAACTA„

3796,AI122689„20,73,TATATTGGAAACTAAGCCAT„ 3797,AI122689„20,67,GGAAACTAAGCCATTTACAC„

3798,AI122689„20,61,TAAGCCATTTACACCTAAGT„

3799,AI122689„20,55,ATTTACACCTAAGTCACTGA„

3800,AI122689„20,49,ACCTAAGTCACTGAAATCAG„

3801,AI122689„20,43,GTCACTGAAATCAGGTTAGA„ 3802,AI122689„20,37,GAAATCAGGTTAGAATGTTT„

3803,AI122689„20,31,AGGTTAGAATGTTTTTTTGA„

3804,AI122689„20,25,GAATGTTTTTTTGACAGAAA„

3805,AI122689„20,19,TTTTTTGACAGAAAAAAAAA„

3806,AI122689„20,13,GACAGAAAAAAAAAAAAAAA„ 3807,AI122689„20,7,AAAAAAAAAAAAAAAAAAAA„

3808,AI122689„20,1,AAAAAAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. AI092623)

GGCGGGGCCTTCCCCCGCTTCCCCCTCCACTCCCCCGCCCGCCCCCGGCCCCGGTTTTCCGATCTCGGCCCAGGGAAAAGCCTTGGT CGCAAATCACCAGTTTGCATTTGCCCCTGGGGCGGGGGCGGCTTTCTGAAACCAGGCTGGGGCTGGGACTCCGCCACCTTCAGCTAA

GGGTACCGAGGTCAGTCCGGGAGTCGCGTCACCGGGACTCGAACCCGCCTTTTCGTTTTCCGAGGCCTAG (SEQ ID NO: 3809)

3810,AI092623„20,314,CTAGGCCTCGGAAAACGAAA„ 3811,AI092623„20,308,CTCGGAAAACGAAAAGGCGG„ 3812,AI092623„20,302,AAACGAAAAGGCGGGTTCGA„

3813,AI092623„20,296,AAAGGCGGGTTCGAGTCCCG„

3814,AI092623„20,290,GGGTTCGAGTCCCGGTGACG„

3815,AI092623„20,284,GAGTCCCGGTGACGCGACTC„ 3816,AI092623„20,278,CGGTGACGCGACTCCCGGAC„

3817,AI092623„20,272,CGCGACTCCCGGACTGACCT„

3818,AI092623„20,266,TCCCGGACTGACCTCGGTAC„

3819,AI092623„20,260,ACTGACCTCGGTACCCTTAG„

3820,AI092623„20,254,CTCGGTACCCTTAGCTGAAG„ 3821,AI092623„20,248,ACCCTTAGCTGAAGGTGGCG„

3822,AI092623„20,242,AGCTGAAGGTGGCGGAGTCC„

3823,AI092623„20,236,AGGTGGCGGAGTCCCAGCCC„

3824,AI092623„20,230,CGGAGTCCCAGCCCCAGCCT„

382₅,AI092623„20,224,CCCAGCCCCAGCCTGGTTTC„ 3826,AI092623„20,218,CCCAGCCTGGTTTCAGAAAG„

3827,AI092623„20,212,CTGGTTTCAGAAAGCCGCCC„

3828,AI092623„20,206,TCAGAAAGCCGCCCCCGCCC„

3829,AI092623„20,200,AGCCGCCCCCGCCCCAGGGG„

3830,AI092623„20,194,CCCCGCCCCAGGGGCAAATG„ 3831 ,AI092623„20, 188,CCCAGGGGCAAATGCAAACT„

3832,AI092623„20,182,GGCAAATGCAAACTGGTGAT„

3833,AI092623„20,176,TGCAAACTGGTGATTTGCGA„

3834,AI092623„20,170,CTGGTGATTTGCGACCAAGG„

3835,AI092623„20,164,ATTTGCGACCAAGGCTTTTC„ 3836,AI092623„20,158,GACCAAGGCTTιTCCCTGGG„

3837,AI092623„20,152,GGCTTTTCCCTGGGCCGAGA„

3838,AI092623„20,146,TCCCTGGGCCGAGATCGGAA„

3839,AI092623„20,140,GGCCGAGATCGGAAAACCGG„

3840,AI092623„20,134,GATCGGAAAACCGGGGCCGG„ 3841,AI092623„20,128,AAAACCGGGGCCGGGGGCGG„

3842,AI092623„20,122,GGGGCCGGGGGCGGGCGGGG„

3843,AI092623„20,116,GGGGGCGGGCGGGGGAGTGG„

3844,AI092623„20,110,GGGCGGGGGAGTGGAGGGGG„

3845,AI092623„20,104,GGGAGTGGAGGGGGAAGCGG„ 3846,AI092623„20,98,GGAGGGGGAAGCGGGGGAAG„

3847,AI092623„20,92_>GGAAGCGGGGGAAGGCCCCG„

3848,AI092623„20,86,GGGGGAAGGCCCCGCCCCCC„

3849,AI092623„20,80,AGGCCCCGCCCCCCCGCCTC„

3850,AI092623„20,74,CGCCCCCCCGCCTCAGCTTC„ 3851,AI092623„20,68,CCCGCCTCAGCTTCTGTCGA„

3852,AI092623„20,62,TCAGCTTCTGTCGAAGAAAA„

3853,AI092623„20,56,TCTGTCGAAGAAAATGGCCT„

3854,AI092623„20,50,GAAGAAAATGGCCTCCTGGG„

3855,AI092623„20,44,AATGGCCTCCTGGGGCCGAT„ 3856,AI092623„20,38,CTCCTGGGGCCGATTTGGTC„

3857,AI092623„20,32,GGGCCGATTTGGTCTTTTCA„

3858,AI092623„20,26,ATTTGGTCTTTTCAAAAAAA„

3859,AI092623„20,20,TCTTTTCAAAAAAAAAAAAA„

3860,AI092623„20,14,CAAAAAAAAAAAAAAAAAAA„ 3861,AI092623„20,8,AAAAAAAAAAAAAAAAAAAA„

3862,AI092623„20,2,AAAAAAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. AI095492) _{ττττττττττττττχτττττTAAAAAAATAAAATCTCTCCTTT}^^

TTTTAAAAAGCACCACTGGGCAACAATCAAAGGGCTTCAGGTAAAAGTCACCGATGGAGGTTAAGGGGGGTCTGCAAAAGTTTCAT GAATAAAACAATGGTTGTGATGGTGAACTGAAGGGTGGCTAGATGGCTGGTATTGTTTCTGGTGTGATGGTGCTCCCAGAGAGACT

GAAATTTGAGTCAGTGGACTAGGAGAGGAAGATCCACCCTCAGTGGGGGTGGGCACCCTCCAACCGGCTGCCAGCGCGGCTAGAAC

AAGGCAGGCAGAAAAAAGTAGGTAAGCTAGCTTGCTGAGTCTTCTGGCTTTCGTCTTTACCCCATGCTGGATGCTTCTGTCCATTCC

TCCTGCCCTTGGACATCACACTC

(SEQ ID NO: 3863)

3864,AI09₅492„20,437,GAGTGTGATGTCCAAGGGCA„

3865,AI095492„20,431,GATGTCCAAGGGCAGGAGGA„

3866,AI095492„20,425,CAAGGGCAGGAGGAATGGAC„

3867,AI095492„20,419,CAGGAGGAATGGACAGAAGC„ 3868,AI095492„20,413,GAATGGACAGAAGCATCCAG„

3869,AI095492„20,407,ACAGAAGCATCCAGCATGGG„

3870,AI095492„20,401,GCATCCAGCATGGGGTAAAG„

3871,AI095492„20,395,AGCATGGGGTAAAGACGAAA„

3872,AI095492„20,389,GGGTAAAGACGAAAGCCAGA„ 3873,AI095492„20,383,AGACGAAAGCCAGAAGACTC„

3874,AI095492„20,377,AAGCCAGAAGACTCAGCAAG„

3875,AI095492„20,371,GAAGACTCAGCAAGCTAGCT„

3876,AI095492„20,365,TCAGCAAGCTAGCTTACCTA„

3877,AI095492„20,359,AGCTAGCTTACCTACTTTTT„ 3878,AI095492„20,353,CTTACCTACTTTTTTCTGCC„ 3879.AI095492 ,,20,347,TACTTTTTTCTGCCTGCCTT„

3880,AI095492„20,341,TTTCTGCCTGCCTTGTTCTA„

3881 ,AI095492„20,335,CCTGCCTTGTTCTAGCCGCG„

3882,AI095492„20,329,TTGTTCTAGCCGCGCTGGCA„

3883,AI095492„20,323,TAGCCGCGCTGGCAGCCGGT„

3884,AI095492„20,317,CGCTGGCAGCCGGTTGGAGG„

3885,AI095492„20,311,CAGCCGGTTGGAGGGTGCCC„

3886,AI095492„20,305,GTTGGAGGGTGCCCACCCCC„

3887,AI095492„20,299,GGGTGCCCACCCCCACTGAG„

3888,AI095492„20,293,CCACCCCCACTGAGGGTGGA„

3889,AI095492„20,287,CCACTGAGGGTGGATCTTCC„

3890,AI095492„20,281,AGGGTGGATCTTCCTCTCCT„

3891,AI095492„20,275,GATCTTCCTCTCCTAGTCCA„

3892,AI095492„20,269,CCTCTCCTAGTCCACTGACT„

3893,AI095492,,20,263,CTAGTCCACTGACTCAAATT„

3894,AI095492„20,257,CACTGACTCAAATTTCAGTC„

3895,AI095492„20,251,CTCAAATTTCAGTCTCTCTG„

3896,AI095492„20,245,TTTCAGTCTCTCTGGGAGCA„

3897,AI095492„20,239,TCTCTCTGGGAGCACCATCA„

3898,AI095492„20,233,TGGGAGCACCATCACACCAG„

3899,AI095492„20,227,CACCATCACACCAGAAACAA„

3900,AI095492„20,221,CACACCAGAAACAATACCAG„

3901,AI095492„20,215,AGAAACAATACCAGCCATCT„

3902,AI095492„20,209,AATACCAGCCATCTAGCCAC„

3903,AI095492„20,203,AGCCATCTAGCCACCCTTCA„

3904,AI095492„20,197,CTAGCCACCCTTCAGTTCAC„

3905,AI095492„20, 191 ,ACCCTTCAGTTCACCATCAC„

3906,AI095492„20,185,CAGTTCACCATCACAACCAT„

3907,AI095492„20, 179,ACCATCACAACCATTGTTTT„

3908,AI095492„20,173,ACAACCATTGTTTTATTCAT„

3909,AI095492„20, 167,ATTGTTTTATTCATGAAACT„

3910,AI095492„20, 161 ,TTATTCATGAAACTTTTGCA„

3911,AI095492„20,155₎ATGAAACTTTTGCAGACCCC„

3912,AI095492„20,149,CTTTTGCAGACCCCCCTTAA„

3913,AI095492„20,143,CAGACCCCCCTTAACCTCCA„

3914,AI095492„20,137,CCCCTTAACCTCCATCGGTG„

3915,AI095492„20, 131 ,AACCTCCATCGGTGACTTTT„

3916,A1095492„20,12₅,CATCGGTGACTTTTACCTGA„

3917,AI095492„20,119,TGACTTTTACCTGAAGCCCT„

3918,AI095492„20, 113,TTACCTGAAGCCCTTTGATT„

3919,AI095492„20,107,GAAGCCCTTTGATTGTTGCC„

3920,AI095492„20,101,CTTTGATTGTTGCCCAGTGG„

3921,AI095492„20,95,TTGTTGCCCAGTGGTGCTTT„

3922,AI095492„20,89,CCCAGTGGTGCTTTTTAAAA„

3923,AI095492„20,83,GGTGCTTTTTAAAATAATTT„

3924,AI095492„20,77,TTTTAAAATAATTTCCATAG„

3925,AI095492„20,71,AATAATTTCCATAGTTTTTT„

3926,AI095492„20,65,TTCCATAGTTTTTTTTACAC„

3927,AI095492„20,59,AGTTTTTTTTACACCTTTAG„

3928,AI095492„20,53,TTTTACACCTTTAGTTGGCA„

3929,AI095492„20,47,ACCTTTAGTTGGCATTTTAC„

3930,AI095492„20,41,AGTTGGCATTTTACTGTAAA„

3931,AI095492„20,35,CATTTTACTGTAAAGGAGAG„

3932,AI095492„20,29,ACTGTAAAGGAGAGATTTTA„

3933,AI095492„20,23,AAGGAGAGATTTTATTTTTT„

3934,AI095492„20,17,AGATTTTATTTTTTTAAAAA„

3935,AI095492„20,11,TATTTTTTTAAAAAAAAAAA„

3936,AI095492„20,5,TTTAAAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. AI138216)

TGGTTTTGTGAACTGCTTTTATTTCATTTGGTTTTATATTGGAATCAATTCACCATGACATTTAATAGCCTTCAAAACAGGATTTTTGT

AATGGCTGCGTGTTAGTCCATCATATTAACATTTATTTATACATTCCTCTATTTTGGACGTAACAGATACTATTTCGGAAGATTTGTTT

TTTATAATCTCTCTAAGATGAATATTTTTCTCCTAGAATGTAAACACTATAAAGGCAGAGAGTTTGTCTTACTGATCACAATACCCTC

AACCCCCCAGAAGTGCCTGACACATAGTTGGAGCTCAACAGGGATGGATGGATGGATGGATGGATG

(SEQ ID NO: 3937)

3938,AI138216„20,313,CATCCATCCATCCATCCATC„ 3939,AH38216„20,307,TCCATCCATCCATCCATCCC„ 3940,AI138216„20,301,CATCCATCCATCCCTGTTGA„ 3941,AI138216„20,295,TCCATCCCTGTTGAGCTCCA„ 3942,AI138216„20,289,CCTGTTGAGCTCCAACTATG„ 3943,AI138216„20,283,GAGCTCCAACTATGTGTCAG„ 3944,AI138216„20,277,CAACTATGTGTCAGGCACTT„ 3945,AI138216„20,271,TGTGTCAGGCACTTCTGGGG„ 3946,AI138216„20,265,AGGCACTTCTGGGGGGTTGA„ 3947,AI138216„20,259,TTCTGGGGGGTTGAGGGTAT„ 3948₁AI138216„20,253₎GGGGTTGAGGGTATTGTGAT„

3949,AI138216„20,247,GAGGGTATTGTGATCAGTAA„

3950,AI138216„20,241,ATTGTGATCAGTAAGACAAA„

3951,AI138216„20,235,ATCAGTAAGACAAACTCTCT„ 3952,AI138216„20,229,AAGACAAACTCTCTGCCTTT„

3953,AI138216„20,223,AACTCTCTGCCTTTATAGTG„

3954,AI138216„20,217,CTGCCTTTATAGTGTTTACA„

3955,AI138216„20,211,TTATAGTGTTTACATTCTAG„

3956,AI138216„20,205,TGTTTACATTCTAGGAGAAA„ 3957,AI138216„20,199,CATTCTAGGAGAAAAATATT„

3958,AI138216„20,193,AGGAGAAAAATATTCATCTT„

3959,AI138216„20,187,AAAATATTCATCTTAGAGAG„

3960,AI138216„20,181,TTCATCTTAGAGAGATTATA„

3961,AI138216„20,175,TTAGAGAGATTATAAAAAAC„ 3962.AI138216„20, 169,AGATTATAAAAAACAAATCT„

3963,AI138216„20,163,TAAAAAACAAATCTTCCGAA„

3964,AI138216„20,157.ACAAATCTTCCGAAATAGTA,,

3965,AI138216„20, 151 ,CTTCCGAAATAGTATCTGTT„

3966.AI138216„20, 145,AAATAGTATCTGTTACGTCC„ 3967,AI138216„20,139,TATCTGTTACGTCCAAAATA„

3968,AI138216„20, 133,TTACGTCCAAAATAGAGGAA„

3969,AI138216„20,127,CCAAAATAGAGGAATGTATA„

3970,AI138216„20, 121 ,TAGAGGAATGTATAAATAAA„

3971 ,AI138216„20, 115,AATGTATAAATAAATGTTAA„ 3972,AI138216„20,109,TAAATAAATGTTAATATGAT„

3973,AI138216„20,103,AATGTTAATATGATGGACTA„

3974.AI138216„20,97,AATATGATGGACTAACACGC„

3975,AI138216„20,91 ,ATGGACTAACACGCAGCCAT„

3976.AI138216„20,85,TAACACGCAGCCATTACAAA„ 3977,AI138216„20,79,GCAGCCATTACAAAAATCCT„

3978,AI138216„20,73,ATTACAAAAATCCTGTTTTG„

3979.AI138216„20,67,AAAATCCTGTTTTGAAGGCT„

3980.AI138216„20,61 ,CTGTTTTGAAGGCTATTAAA„

3981 , All 38216„20,55,TGAAGGCTATTAAATGTCAT„ 3982,AI138216„20,49,CTATTAAATGTCATGGTGAA„

3983,AI138216„20,43,AATGTCATGGTGAATTGATT„

3984.AI138216„20,37,ATGGTGAATTGATTCCAATA„

3985,AI138216„20,31,AATTGATTCCAATATAAAAC„

3986,AI138216„20,25,TTCCAATATAAAACCAAATG„ 3987,AI138216„20,19,TATAAAACCAAATGAAATAA„

3988,AI138216„20,13,ACCAAATGAAATAAAAGCAG„

3989,AI138216„20,7,TGAAATAAAAGCAGTTCACA„

3990,AI138216„20,1₎AAAAGCAGTTCACAAAACCA„

(GENBANK ACCESSION NO. AI128305) TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAATTCAATGACCATTTTATTGAGCACTAAGGATTTCATTATAACAAAGTCT

GCATTTGACATGTCCATATAAACCAAAATAATAAACTTGGGTTAAATAAAAGTACCTTGACACAGGAGGATCACCTGAGTAGGGGA

GTTCAAGACCAGCCCAAGCAACACAGCAAGATGACCATTTCAAAAAACAAAACAAAACAAAAACCCTGCAGGTATTTTTATCTAAC

TTTTACATATCCTTTGTTTTGGAATGCTCACTTGCTTAATTGACTAAATAGGTGGAAGTCAAATCTTCTCTAGCCATTGATGTGAACC

AATGAAACTATATTCTCAAGGAGTATTTTGTTAGCTTGGTACCAGCTACCTGACAAATTTGAAAATACAGCT (SEQ ID NO: 3991)

3992,AI128305„20,404,AGCTGTATTTTCAAATTTGT„

3993,AI128305„20,398,ATTTTCAAATTTGTCAGGTA„

3994,AI128305„20,392,AAATTTGTCAGGTAGCTGGT„ 3995,AI128305„20,386,GTCAGGTAGCTGGTACCAAG„

3996,AI128305„20,380,TAGCTGGTACCAAGCTAACA„

3997,AI128305„20,374,GTACCAAGCTAACAAAATAC„

3998_JAI128305„20,368,AGCTAACAAAATACTCCTTG„

3999,AI128305„20,362,CAAAATACTCCTTGAGAATA„ 4000,AI128305„20,356,ACTCCTTGAGAATATAGTTT„

4001,AI128305„20,350,TGAGAATATAGTTTCATTGG„

4002,AI128305„20,344,TATAGTTTCATTGGTTCACA„

4003,AI128305„20,338,TTCATTGGTTCACATCAATG„

4004,AI128305„20,332,GGTTCACATCAATGGCTAGA„ 4005,AI128305„20,326,CATCAATGGCTAGAGAAGAT„

4006,AI128305„20,320,TGGCTAGAGAAGATTTGACT„

4007,AI128305„20,314,GAGAAGATTTGACTTCCACC„

4008,AI128305„20,308,ATTTGACTTCCACCTATTTA„

4009,AI128305„20,302,CTTCCACCTATTTAGTCAAT„ 4010,AI128305„20,296,CCTATTTAGTCAATTAAGCA„

4011,AI128305„20,290,TAGTCAATTAAGCAAGTGAG„

4012,AI128305„20,284,ATTAAGCAAGTGAGCATTCC„

4013,AI128305„20,278,CAAGTGAGCATTCCAAAACA„

4014,AI128305„20,272,AGCATTCCAAAACAAAGGAT„ 4015,AI128305„20,266,CCAAAACAAAGGATATGTAA„ 4016,AI128305„20,260,CAAAGGATATGTAAAAGTTA„

4017,AI128305„20,254,ATATGTAAAAGTTAGATAAA„

4018,AI128305„20,248,AAAAGTTAGATAAAAATACC„

4019,AI128305„20,242,TAGATAAAAATACCTGCAGG„ 4020,AI128305„20,236,AAAATACCTGCAGGGTTTTT„

4021,AI128305„20,230,CCTGCAGGGTTTTTGTTTTG„

4022,AI128305„20,224,GGGTTTTTGTTTTGTTTTGT„

4023,AI128305„20,218,TTGTTTTGTTTTGTTTTTTG„

4024,AI128305„20,212,TGTTTTGTTTTTTGAAATGG„ 402₅,AI128305„20,206,GTTTTTTGAAATGGTCATCT„

4026,AI128305„20,200,TGAAATGGTCATCTTGCTGT„

4027,AI128305„20,194,GGTCATCTTGCTGTGTTGCT„

4028,AI128305„20,188,CTTGCTGTGTTGCTTGGGCT„

4029,AI128305„20,182,GTGTTGCTTGGGCTGGTCTT„ 4030,AI128305„20,176,CTTGGGCTGGTCTTGAACTC„

4031 ,AI128305„20, 170,CTGGTCTTGAACTCCCCTAC„

4032,AI128305„20,164,TTGAACTCCCCTACTCAGGT„

4033,AI128305„20,158,TCCCCTACTCAGGTGATCCT„

4034,AI128305„20,152,ACTCAGGTGATCCTCCTGTG„ 4035,AI128305„20,146,GTGATCCTCCTGTGTCAAGG„

4036,Ali28305„20,140,CTCCTGTGTCAAGGTACTTT„

4037,AI128305„20,134,TGTCAAGGTACTTTTATTTA„

4038,AI128305„20,128,GGTACTTTTATTTAACCCAA„

4039,AI128305„20,122,TTTATTTAACCCAAGTTTAT„ 4040,AI128305„20,116,TAACCCAAGTTTATTATTTT„

4041 ,AI128305„20, 110,AAGTTTATTATTTTGGTTTA„

4042,AI128305„20,104,ATTATTTTGGTTTATATGGA„

4043,AI128305„20,98,TTGGTTTATATGGACATGTC„

4044,AI128305„20,92,TATATGGACATGTCAAATGC„ 404₅,AI12830₅„20,86,GACATGTCAAATGCAGACTT„

4046,AI12830₅„20,80,TCAAATGCAGACTTTGTTAT„

4047,AI128305„20,74,GCAGACTTTGTTATAATGAA„

4048,AI128305„20,68,TTTGTTATAATGAAATCCTT„

4049,AI128305„20,62,ATAATGAAATCCTTAGTGCT„ 4050,AI128305„20,56_;AAATCCTTAGTGCTCAATAA„

4051,AI128305„20,50,TTAGTGCTCAATAAAATGGT„

4052,AI128305„20,44,CTCAATAAAATGGTCATTGA„

40₅3,AI128305„20,38,AAAATGGTCATTGAATTTAA„

4054,AI128305„20,32,GTCATTGAATTTAAAAAAAA„ 4055,AI128305„20,26,GAATTTAAAAAAAAAAAAAA„

4056,AI128305„20,20,AAAAAAAAAAAAAAAAAAAA„

4057.AI128305„20, 14,AAAAAAAAAAAAAAAAAAAA„

4058_>AI128305„20,8,AAAAAAAAAAAAAAAAAAAA„

4059,AI128305„20,2,AAAAAAAAAAAAAAAAAAAA„ (GENBANK ACCESSION NO. AI125228)

CAGCCATACTTCATTTCCACTCTGATGTTTTCCAGTCATAATTACTGCTTAAATATTCTTTTATACCATGCTAGATTTTTCCAATTGGT ATGGCAGCCTATTGCTGAAAGCCACCTTAAAACACTTTTAACTCAACATCCTTTTTTACAAAGGAGCAAATTGATGTTATGATTTCAT CTAATACTATAACAATAAAAAAGGAAATAAGTCCCAAATGAATATTAAAATAACCAAAAAATTGTTATGTAATTAAAATCAGGAAG TTTGGTAAGTTAGATAGTAGGAAATAAAAAATTATTTCAG

(SEQ ID NO: 4060)

4061,AI125228„20,374₁CTGAAATAATTTTTTATTTC„

4062,AI125228„20,368,TAATTTTTTATTTCCTACTA„ 4063,AI125228„20,362,TTTATTTCCTACTATCTAAC„

4064,AI125228„20,356,TCCTACTATCTAACTTACCA„

406₅,AI125228„20,350,TATCTAACTTACCAAACTTC„

4066,AI125228„20,344,ACTTACCAAACTTCCTGATT„

4067,AI125228„20,338,CAAACTTCCTGATTTTAATT„ 4068,AI125228„20,332,TCCTGATTTTAATTACATAA„

4069,AI125228„20,326,TTTTAATTACATAACAATTT„

4070,AI12₅228„20,320 TACATAACAATTTTTTGGT„

4071,AI12₅228„20,314,AACAATTTTTTGGTTATTTT„

4072,AI125228,,20,308,TTTTTGGTTATTTTAATATT„ 4073,AI12₅228„20,302,GTTATTTTAATATTCATTTG„

4074,AI125228„20,296,TTAATATTCATTTGGGACTT„

4075,AI125228„20,290,TTCATTTGGGACTTATTTCC„

4076,AI125228„20,284,TGGGACTTATTTCCTTTTTT„

4077,AI125228„20,278,TTATTTCCTTTTTTATTGTT„ 4078,AI125228„20,272,CCTTTTTTATTGTTATAGTA„

4079,AI125228„20,266,TTATTGTTATAGTATTAGAT„

4080,AI125228„20,260,TTATAGTATTAGATGAAATC„

4081,AI125228„20,254,TATTAGATGAAATCATAACA„

4082,AI125228„20,248,ATGAAATCATAACATCAATT„ 4083,AI125228„20,242,TCATAACATCAATTTGCTCC„ 4084,AI125228„20,236,CATCAATTTGCTCCTTTGTA„

4085,AI125228„20,230,TTTGCTCCTTTGTAAAAAAG„

4086,AI125228„20,224,CCTTTGTAAAAAAGGATGTT„

4087,AI12₅228„20,218,TAAAAAAGGATGTTGAGTTA„ 4088,AI12₅228„20,212,AGGATGTTGAGTTAAAAGTG„

4089,AI12₅228„20,206,TTGAGTTAAAAGTGTTTTAA„

4090,AI125228„20,200,TAAAAGTGTTTTAAGGTGGC„

4091 ,AI125228„20, 194,TGTTTTAAGGTGGCTTTCAG„

4092,AI125228„20,188,AAGGTGGCTTTCAGCAATAG„ 4093,AI125228„20,182,GCTTTCAGCAATAGGCTGCC„

4094,AI125228„20,176,AGCAATAGGCTGCCATACCA„

4095,AI125228„20,170,AGGCTGCCATACCAATTGGA„

4096,AI125228„20,164,CCATACCAATTGGAAAAATC„

4097,AI125228„20,158,CAATTGGAAAAATCTAGCAT„ 4098,AI125228„20,152,GAAAAATCTAGCATGGTATA„

4099,AI125228„20,146,TCTAGCATGGTATAAAAGAA„

4100,AI125228„20,140,ATGGTATAAAAGAATATTTA„

4101 ,AI125228„20, 134,TAAAAGAATATTTAAGCAGT„

4102,AI125228„20,128,AATATTTAAGCAGTAATTAT„ 4103,AI125228„20,122,TAAGCAGTAATTATGACTGG„

4104,AI125228„20,116,GTAATTATGACTGGAAAACA„

4105,AI125228„20,110,ATGACTGGAAAACATCAGAG„

4106,AI125228„20,104,GGAAAACATCAGAGTGGAAA„

4107,AI125228„20,98,CATCAGAGTGGAAATGAAGT„ 4108,AI125228„20,92,AGTGGAAATGAAGTATGGCT„

4109,AI125228„20,86,AATGAAGTATGGCTGAGAAA„

4110,AI125228„20,80,GTATGGCTGAGAAACCTTTT„

4111,AI125228„20,74,CTGAGAAACCTTTTTGCTTT„

4112,AI125228„20,68,AACCTTTTTGCTTTTAGCTT„ 4113,AI125228„20,62,TTTGCTTTTAGCTTTTTTTG„

4114,AI125228„20,56,TTTAGCTTTTTTTGGAGTTC„

4115,AI125228„20,50,TTTTTTTGGAGTTCATTCCA„

4116,AI125228„20,44,TGGAGTTCATTCCAATAAAA„

4117,AI125228„20,38,TCATTCCAATAAAATGAAAT„ 4118,AI125228„20,32,CAATAAAATGAAATTATAGA„

4119,AI125228„20,26,AATGAAATTATAGAAACTTA„

4120,AI125228„20,20,ATTATAGAAACTTAAAAAAA„

4I21,AI125228„20,14,GAAACTTAAAAAAAAAAAAA„

4122,AI125228„20,8,TAAAAAAAAAAAAAAAAAAA„ 4123,AI125228„20,2,AAAAAAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. AI041482)

GTGTAACATTGTAAAGCACATTACTCACATGTCTGTCATTTAAACCTGCTGCACTGCCAGTCATGTAACAGTAGTAAATATGGTTAT GTACAGTAGATTATATACAGTACATAATAATGAATAGTAATAAGTGACCACATTACTGGTTTATATATTTTTATACTATTTATTGTTA TTTTAGAATGTATTCCTTCTACTTACTAAAAAAGAAAAGTTAACTCAAAAACAAGCCTCAAGCAGATGCTTCAGAAGACATTCTAGA

AGTCATTGT (SEQ ID NO: 4124)

4125,AI041482„20,342,ACAATGACTTCTAGAATGTC„ 4126,AI041482„20,336,ACTTCTAGAATGTCTTCTGA„

4127,AI041482„20,330,AGAATGTCTTCTGAAGCATC„

4128,AI041482„20,324,TCTTCTGAAGCATCTGCTTG„

4129.AI041482„20,318.GAAGCATCTGCTTGAGGCTT,,

4130,AI041482„20,312,TCTGCTTGAGGCTTGTTTTT„ 4131,AI041482„20,306,TGAGGCTTGTTTTTGAGTTA„

4132,AI041482„20,300,TTGTTTTTGAGTTAACTTTT„

4133,AI041482„20,294,TTGAGTTAACTTTTCTTTTT„

4134,AI041482„20,288,TAACTTTTCTTTTTTAGTAA„

4135,AI041482„20,282,TTCTTTTTTAGTAAGTAGAA„ 4136,AI041482„20,276,TTTAGTAAGTAGAAGGAATA„

4137,AI041482„20,270,AAGTAGAAGGAATACATTCT„

4138,AI041482„20,264,AAGGAATACATTCTAAAATA„

4139,AI041482„20,258,TACATTCTAAAATAACAATA„

4140,AI041482„20,252,CTAAAATAACAATAAATAGT„ 4141,AI041482„20,246,TAACAATAAATAGTATAAAA„

4142,AI041482„20,240,TAAATAGTATAAAAATATAT„

4143,AI041482„20,234,GTATAAAAATATATAAACCA„

41₄ ,AI041482„20,228,AAATATATAAACCAGTAATG„

4145,AI041482„20,222,ATAAACCAGTAATGTGGTCA„ 4146,AI041482„20,216,CAGTAATGTGGTCACTTATT„

4147,AI041482„20,210,TGTGGTCACTTATTACTATT„

4148,AI041482„20,204,CACTTATTACTATTCATTAT„

4149,AI041482„20,198,TTACTATTCATTATTATGTA„

4150,AI041482„20, 192,TTCATTATTATGTACTGTAT„ 4151 ,AI041482„20, 186,ATTATGTACTGTATATAATC„ 41₅2,AI041482„20,180,TACTGTATATAATCTACTGT„

41₅3,AI041482„20,174,ATATAATCTACTGTACATAA„

4154,AI041482„20,168,TCTACTGTACATAACCATAT„

4155,AI041482„20,162,GTACATAACCATATTTACTA„ 4156,AI041482„20,156,AACCATATTTACTACTGTTA„

4157,AI041482„20,150,ATTTACTACTGTTACATGAC„

4158,AI041482„20,144,TACTGTTACATGACTGGCAG„

4159,AI041482„20,138,TACATGACTGGCAGTGCAGC„

4160,AI041482„20,132,ACTGGCAGTGCAGCAGGTTT„ 4161,AI041482„20,126,AGTGCAGCAGGTTTAAATGA„

4162,AI041482„20,120,GCAGGTTTAAATGACAGACA„

4163,AI041482„20,114,TTAAATGACAGACATGTGAG„

4164,AI041482„20,108,GACAGACATGTGAGTAATGT„

4165,AI041482„20,102,CATGTGAGTAATGTGCTTTA„ 4166,AI041482„20,96,AGTAATGTGCTTTACAATGT„

4167,AI041482„20,90,GTGCTTTACAATGTTACACT„

4168,AI041482,,20,84,TACAATGTTACACTGGCTAT„

4169,AI041482„20,78,GTTACACTGGCTATGTCATT„

4170,AI041482„20,72,CTGGCTATGTCATTAGGTGA„ 4171,AI041482„20,66,ATGTCATTAGGTGATTGGAA„

4172,AI041482„20,60,TTAGGTGATTGGAATTTTTT„

4173,AI041482„20,54,GATTGGAATTTTTTAGCACT„

4174,AI041482„20,48,AATTTTTTAGCACTATTAAA„

4175,AI041482„20,42,TTAGCACTATTAAAATGTTA„ 4176,AI041482„20,36,CTATTAAAATGTTATGAGAG„

4177,AI041482„20,30,AAATGTTATGAGAGCACTGT„

4178,AI041482„20,24,TATGAGAGCACTGTCAAAAA„

4179,AI041482„20,18,AGCACTGTCAAAAAAAAAAA„

4180,AI041482„20,12,GTCAAAAAAAAAAAAAAAAA„ 4181,AI041482„20₎6,AAAAAAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. AI051839)

CTTTAAAAACAATCTACTTAATTGTCAACAACCAAGTGTATGGAAATTTACGTAAAATCCTGTTTACAGATGAGAGAAGGCGGCTGC TGTGGTGACAGCACACAGTCAGCAAAGAGGTCCAGAGGATGACGTGCAGCTTCCCGGCGGCCTGGAGAGCTCCCCAGGTCTCACCC CATCCCGCTTCCATCTCAAGGCTCTGGGCACCCCCCTCTTGCAGACCTGCTTCTATTTCTTTGGACAGTTTGGGAAAATCACGCTCTT

TAACCCTAAACACTTCGGATCACTTCAAAACAAGATGCTCAGAAAAGGGAAACTCTAATCCGTCAACCAGGGAAAGATAGTAACTG TCTAATCGCACAGCATCCCACAGTGAGCAGCCACC (SEQ ID NO: 4182) 4183,AI051839,,20,454,GGTGGCTGCTCACTGTGGGA„

4184,AI051839„20,448,TGCTCACTGTGGGATGCTGT„

4185,AI051839„20,442,CTGTGGGATGCTGTGCGATT„

4186,AI051839„20,436,GATGCTGTGCGATTAGACAG„

4187,AI051839„20,430_>GTGCGATTAGACAGTTACTA„ 4188,AI051839,,20_>424,TTAGACAGTTACTATCTTTC„

4189,AI051839„20,418₎AGTTACTATCTTTCCCTGGT„

4190,AI051839„20,412_JTATCTTTCCCTGGTTGACGG„

4191,AI051839„20,406,TCCCTGGTTGACGGATTAGA„

4192,AI051839„20,400_>GTTGACGGATTAGAGTTTCC„ 4193,AI051839„20,394,GGATTAGAGTTTCCCTTTTC„

4194,AI051839,,20,388,GAGTTTCCCTTTTCTGAGCA„

4195,AI051839„20,382,CCCTTTTCTGAGCATCTTGT„

4196,AI051839„20,376,TCTGAGCATCTTGTTTTGAA„

4197,AI051839„20,370,CATCTTGTTTTGAAGTGATC„ 4198,AI051839„20,364,GTTTTGAAGTGATCCGAAGT„

4199,AI051839„20,358,AAGTGATCCGAAGTGTTTAG„

4200,AI051839„20,352,TCCGAAGTGTTTAGGGTTAA„

4201 ,AI051839„20,346,GTGTTTAGGGTTAAAGAGCG„

4202,AI051839„20,340,AGGGTTAAAGAGCGTGATTT„ 4203.AI051839„20,334,AAAGAGCGTGATπTCCCAA„

4204,AI051839„20,328,CGTGATTTTCCCAAACTGTC„

4205,AI051839„20,322,TTTCCCAAACTGTCCAAAGA„

4206,AI051839„20,31 ό.AAACTGTCCAAAGAAATAGA,,

4207,AI051839„20,310,TCCAAAGAAATAGAAGCAGG„ 4208,AI051839„20,304,GAAATAGAAGCAGGTCTGCA„

4209,AI051839„20,298,GAAGCAGGTCTGCAAGAGGG„

4210,AI051839„20,292,GGTCTGCAAGAGGGGGGTGC„

4211 ,AI051839„20,286,CAAGAGGGGGGTGCCCAGAG„

4212.AI051839„20,280,GGGGGTGCCCAGAGCCTTGA„ 4213,AI051839„20,274,GCCCAGAGCCTTGAGATGGA„

4214,AI051839„20,268,AGCCTTGAGATGGAAGCGGG„

4215,AI051839„20,262,GAGATGGAAGCGGGATGGGG„

4216.AI051839„20,256,GAAGCGGGATGGGGTGAGAC„

4217,AI051839„20,250,GGATGGGGTGAGACCTGGGG„ 4218.AI051839„20,244,GGTGAGACCTGGGGAGCTCT„ 4219,AI051839„20,238,ACCTGGGGAGCTCTCCAGGC„

4220,AI051839„20,232,GGAGCTCTCCAGGCCGCCGG„

4221,AI051839„20,226,CTCCAGGCCGCCGGGAAGCT„

4222,AI051839„20,220,GCCGCCGGGAAGCTGCACGT„ 4223,AI051839„20,214,GGGAAGCTGCACGTCATCCT„

4224,AI051839„20,208,CTGCACGTCATCCTCTGGAC„

4225.AI051839„20,202,GTCATCCTCTGGACCTCTTT„

4226,AI051839„20,196,CTCTGGACCTCTTTGCTGAC„

4227,AI051839„20,190,ACCTCTTTGCTGACTGTGTG„ 4228,AI051839„20, 184,TTGCTGACTGTGTGCTGTCA„

4229,AI051839„20,178,ACTGTGTGCTGTCACCACAG„

4230,AI051839„20,172,TGCTGTCACCACAGCAGCCG„

4231 ,AI051839„20, 166,CACCACAGCAGCCGCCTTCT„

4232.AI051839„20, 160,AGCAGCCGCCTTCTCTCATC„ 4233,AI051839„20, 154,CGCCTTCTCTCATCTGTAAA„

4234.AI051839„20, 148,CTCTCATCTGTAAACAGGAT„

4235,AI051839„20,142,TCTGTAAACAGGATTTTACG„

4236,AI051839„20,136,AACAGGATTTTACGTAAATT„

4237.AI051839„20, 130,ATTTTACGTAAATTTCCATA„ 4238.AI051839„20, 124,CGTAAATTTCCATACACTTG„

4239,AI051839„20,118,TTTCCATACACTTGGTTGTT₎₎

4240.AI051839„20, 112,TACACTTGGTTGTTGACAAT„

4241,AI051839„20,106,TGGTTGTTGACAATTAAGTA„

4242,AI051839„20,100,TTGACAATTAAGTAGATTGT„ 4243,AI051839„20,94,ATTAAGTAGATTGTTTTTAA„

4244,AI051839,,20,88,TAGATTGTTTTTAAAGATAC„

4245,AI051839„20,82,GTTTTTAAAGATACTTGAAA„

4246.AI051839„20,76,AAAGATACTTGAAATGATAT„

4247.AI051839„20,70,ACTTGAAATGATATCAGAAT„ 4248.AI051839„20,64,AATGATATCAGAATTTCCTA„

4249,AI051839„20,58,ATCAGAATTTCCTAAATATA„

4250,AI051839„20,52,ATTTCCTAAATATATCATTA„

4251,AI051839„20,46,TAAATATATCATTAAAACAG„

4252,AI051839„20,40,TATCATTAAAACAGGAAACT„ 4253,AI051839„20,34,TAAAACAGGAAACTTAGTTA„

4254,AI051839„20,28,AGGAAACTTAGTTACCTAAA„

4255,AI051839,,20,22,CTTAGTTACCTAAAAAAAAA„

4256.AI051839„20, 16.TACCTAAAAAAAAAAAAAAA,,

4257ΛI051839„20, 10,AAAAAAAAAAAAAAAAAAAA„ 4258,AI051839„20,4,AAAAAAAAAAAAAAAAAAAA„ _τ (G_τE_τN_τB_τA_ττN_τK_τ A_ττC_τC_τE_τS_χS_τIO_τN_ττ N_τO_ττ A_τI_τ0_c92_τ4_τ2_c9_τ)_{CGTCTTGCTAGAACCTGGTAGTGCA}

GGTGGGGTTCCGCTCCATGGCGGCAGCAATCAGCAGCTCAAAGGGCCGCCTCAGCTGGGGCTGCACATAGTCTGGCTCCGCTGCTA CTGGTTCCTCATCCACGTCAATGATGTCTTCGTCGACATCATTCTGCTCAAAGGTGGGAGTCTCTGTGCTGGCGCTGGATGTGGGTGT GCCAGGCCTGCTGGCTCTCCTTTCCAGGATCCGGGCATGGGCAATGGCCTTTAGTTCAGTTTTGCTGGCCGATCTGTCCAACAAGTC

AGTGTCACTGCTGGGGGATGTAGTCCGTTTGCCAGATTTGTCCACCAGTCCATTGACATGACCCAGCTCCTTTTTCTG (SEQ ID NO 4259)

4260,AI092429„20,409,CAGAAAAAGGAGCTGGGTCA„ 4261,AI092429„20,403,AAGGAGCTGGGTCATGTCAA„

4262,AI092429„20,397,CTGGGTCATGTCAATGGACT„

4263,AI092429„20,391,CATGTCAATGGACTGGTGGA„

4264,AI092429„20,385,AATGGACTGGTGGACAAATC„

4265,AI092429„20,379,CTGGTGGACAAATCTGGCAA„ 4266,AI092429„20,373,GACAAATCTGGCAAACGGAC„

4267,AI092429„20,367,TCTGGCAAACGGACTACATC„

4268,AI092429„20,361,AAACGGACTACATCCCCCAG„

4269,AI092429„20,355,ACTACATCCCCCAGCAGTGA„

4270,AI092429„20,349,TCCCCCAGCAGTGACACTGA„ 4271,AI092429„20,343,AGCAGTGACACTGACTTGTT„

4272,AI092429„20,337,GACACTGACTTGTTGGACAG„

4273,AI092429„20,331,GACTTGTTGGACAGATCGGC„

4274,AI092429„20,325,TTGGACAGATCGGCCAGCAA„

4275,AI092429„20,319,AGATCGGCCAGCAAAACTGA„ 4276,AI092429„20,313,GCCAGCAAAACTGAACTAAA„

4277,AI092429„20,307,AAAACTGAACTAAAGGCCAT„

4278,AI092429„20,301 ,GAACTAAAGGCCATTGCCCA„

4279,AI092429„20,295,AAGGCCATTGCCCATGCCCG„

4280,AI092429„20,289,ATTGCCCATGCCCGGATCCT„ 4281,AI092429„20,283,CATGCCCGGATCCTGGAAAG„

4282,AI092429„20,277,CGGATCCTGGAAAGGAGAGC„

4283,AI092429„20,271 ,CTGGAAAGGAGAGCCAGCAG„

4284,AI092429„20,265,AGGAGAGCCAGCAGGCCTGG„

4285,AI092429„20,259,GCCAGCAGGCCTGGCACACC„ 4286_JAI092429„20,253,AGGCCTGGCACACCCACATC„ 4287,AI092429„20,247,GGCACACCCACATCCAGCGC„

4288,AI092429„20,241,CCCACATCCAGCGCCAGCAC„

4289,AI092429„20,235,TCCAGCGCCAGCACAGAGAC„

4290,AI092429„20,229,GCCAGCACAGAGACTCCCAC„ 4291,AI092429„20,223,ACAGAGACTCCCACCTTTGA„

4292,AI092429„20,217,ACTCCCACCTTTGAGCAGAA„

4293,AI092429„20,211 ,ACCTTTGAGCAGAATGATGT„

4294,AI092429„20,205,GAGCAGAATGATGTCGACGA„

4295,AI092429„20,199,AATGATGTCGACGAAGACAT„ 4296,AI092429„20,193,GTCGACGAAGACATCATTGA„

4297,AI092429„20,I87,GAAGACATCATTGACGTGGA„

4298,AI092429„20, 181 ,ATCATTGACGTGGATGAGGA„

4299,AI092429„20,175,GACGTGGATGAGGAACCAGT„

4300,AI092429„20, 169,GATGAGGAACCAGTAGCAGC„ 4301,AI092429„20,163,GAACCAGTAGCAGCGGAGCC„

4302,AI092429„20, 157,GTAGCAGCGGAGCCAGACTA„

4303,AI092429„20, 151 ,GCGGAGCCAGACTATGTGCA„

4304,AI092429„20,145,CCAGACTATGTGCAGCCCCA„

430₅,AI092429„20,139,TATGTGCAGCCCCAGCTGAG„ 4306,AI092429„20, 133,CAGCCCCAGCTGAGGCGGCC„

4307,AI092429„20,127,CAGCTGAGGCGGCCCTTTGA„

4308,AI092429„20, 121 ,AGGCGGCCCTTTGAGCTGCT„

4309,AI092429„20, 115,CCCTTTGAGCTGCTGATTGC„

4310,AI092429„20,109,GAGCTGCTGATTGCTGCCGC„ 4311,AI092429„20,103,CTGATTGCTGCCGCCATGGA„

4312,AI092429„20,97,GCTGCCGCCATGGAGCGGAA„

4313,AI092429„20,91,GCCATGGAGCGGAACCCCAC„

4314,AI092429„20,85,GAGCGGAACCCCACCCAATT„

4315,AI092429„20,79,AACCCCACCCAATTTCAGTT„ 4316,AI092429„20,73,ACCCAATTTCAGTTGCCCAA„

4317,AI092429„20,67,TTTCAGTTGCCCAATGAACT„

4318,AI092429„20,61 ,TTGCCCAATGAACTGACTTG„

4319,AI092429„20,5₅,AATGAACTGACTTGTACCCC„

4320,AI092429„20,49,CTGACTTGTACCCCTGCACT„ 4321 ,AI092429„20,43,TGTACCCCTGCACTACCAGG„

4322,AI092429„20,37,CCTGCACTACCAGGTTCTAG„

4323,AI092429„20,31 ,CTACCAGGTTCTAGCAAGAC„

4324,AI092429„20,25,GGTTCTAGCAAGACGAGAAG„

4325,AI092429„20,19,AGCAAGACGAGAAGAAAAAA„ 4326,AI092429„20, 13.ACGAGAAGAAAAAAAAAAAA,,

4327,AI092429„20,7,AGAAAAAAAAAAAAAAAAAA„

4328,AI092429„20, 1 ,AAAAAAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. AI096522) TTTCCCTTGGGGCATAGCTCCACTGGTGGTTACTCTAATGTTTCAAAGGCCTCCACTGTATTCATTAAGCAGGGATCAGATGCCACTA

TCCAAACCCCTCATTCCCTTGACCCCGAACCCAAAAGAGC (SEQ ID NO: 4329)

4330,AI096522„20, 198,GCTCTTTTGGGTTCGGGGTC„ 4331,AI096522„20,192,TTGGGTTCGGGGTCAAGGGA„

4332,AI096₅22„20, 186.TCGGGGTCAAGGGAATGAGG,,

4333,AI096₅22„20,180,TCAAGGGAATGAGGGGTTTG„

4334,AI096₅22„20,174,GAATGAGGGGTTTGGATAGT„

433₅,AI096₅22„20,168,GGGGTTTGGATAGTGGCATC„ 4336,AI096522„20,162,TGGATAGTGGCATCTGATCC„

4337,AI096522„20, 156,GTGGCATCTGATCCCTGCTT„

4338,AI096522„20,150,TCTGATCCCTGCTTAATGAA„

4339,AI096522„20,144,CCCTGCTTAATGAATACAGT„

4340,AI096522„20,138,TTAATGAATACAGTGGAGGC„ 4341,AI096522„20,132,AATACAGTGGAGGCCTTTGA„

4342,AI096522„20,126,GTGGAGGCCTTTGAAACATT„

4343,AI096522„20,120,GCCTTTGAAACATTAGAGTA„

4344,AI096522„20_S114,GAAACATTAGAGTAACCACC„

4345,AI096522„20, 108,TTAGAGTAACCACCAGTGGA„ 4346,AI096522„20, 102,TAACCACCAGTGGAGCTATG„

4347_IAI096522„20,96,CCAGTGGAGCTATGCCCCAA„

4348,AI096522„20,90,GAGCTATGCCCCAAGGGAAA„

4349,AI096522„20,84,TGCCCCAAGGGAAATAATGG„

4350,AI096522„20,78,AAGGGAAATAATGGGGGGTT„ 4351,AI096522„20,72,AATAATGGGGGGTTTGGAAT„

4352,AI096522„20,66,GGGGGGTTTGGAATTTGCTG„

4353,AI096522„20,60,TTTGGAATTTGCTGGTTTCC„

4354,AI096522„20,54,ATTTGCTGGTTTCCTACCTG„

4355,AI096522„20,48,TGGTTTCCTACCTGCTGGGC„ 4356,AI096522„20,42,CCTACCTGCTGGGCCCCATA„ 4357,AI096522„20,36,TGCTGGGCCCCATAAAAGCT„

4358,AI096522„20,30,GCCCCATAAAAGCTGAGTGC„

4359,AI096522„20,24,TAAAAGCTGAGTGCCTGTAA„

4360,AI096522„20, 18,CTGAGTGCCTGTAAAAAAAA„ 4361,AI096522„20,12,GCCTGTAAAAAAAAAAAAAA„

4362,AI096522„20,6,AAAAAAAAAAAAAAAAAAAA„ _τ (G_τE_τN_τB_τA_ττN_τK_τ A_ττC_τC_χE_τS_τS_τIO_τN_ττ N_τO_ττ. A_τI_τ1_A2_A28_A0_A7)_{CAACCAAGGTTTACTTCTC}

TCATCTTCCCTCCAATACCAAGGCTGATCGTGCATATGCTCTCTGGAACACTGATGATTGCCATGGCAAAGAGAAAAAGAGTTCTGG AAGGTCTTGCATCAACAATTAAATGCTATGCTCACACTTAATTCGGAGAACATGTCATGTAGTTCAACCCCATCACAGGGAGGCCAG

GGCATACAATCCTCCTATATTCCTTAAACAGGCGGAAAGAGGAAAAGAAACCAGCGAATGAGTTTGAGAAGCTGCCCTCTGAGAAA GCGAACTCTTAAAAATG (SEQ ID NO: 4363) 4364,AI122807„20,348,CATTTTTAAGAGTTCGCTTT„

4365,AI122807„20,342,TAAGAGTTCGCTTTCTCAGA„

4366,AI122807„20,336,TTCGCTTTCTCAGAGGGCAG„

4367,AI122807„20,330,TTCTCAGAGGGCAGCTTCTC„

4368,AI122807„20,324,GAGGGCAGCTTCTCAAACTC„ 4369,AI122807„20,318,AGCTTCTCAAACTCATTCGC„

4370,AI122807„20,312,TCAAACTCATTCGCTGGTTT„

4371,AI122S07„20,306,TCATTCGCTGGTTTCTTTTC„

4372,AI122807„20,300,GCTGGTTTCTTTTCCTCTTT„

4373,AI122807„20,294,TTCTTTTCCTCTTTCCGCCT„ 4374,AI122807„20,288,TCCTCTTTCCGCCTGTTTAA„

4375,AI122807„20,282,TTCCGCCTGTTTAAGGAATA„

4376,AI122807„20,276,CTGTTTAAGGAATATAGGAG„

4377,AI122807„20,270,AAGGAATATAGGAGGATTGT„

4378,AI122807„20,264,TATAGGAGGATTGTATGCCC„ 4379,AI122807„20,258,AGGATTGTATGCCCTGGCCT„

4380,AI122807,,20,252,GTATGCCCTGGCCTCCCTGT„

4381,AH22807„20,246,CCTGGCCTCCCTGTGATGGG„

4382,AI122807„20,240,CTCCCTGTGATGGGGTTGAA„

4383,AI122807„20,234,GTGATGGGGTTGAACTACAT„ 4384,AI122807„20,228,GGGTTGAACTACATGACATG„

4385,AI122807„20,222,AACTACATGACATGTTCTCC„

4386,AI122807„20,216,ATGACATGTTCTCCGAATTA„

4387,AI122807„20,210,TGTTCTCCGAATTAAGTGTG„

4388,AI122807„20,204,CCGAATTAAGTGTGAGCATA„ 4389,AI122S07„20,198,TAAGTGTGAGCATAGCATTT„

4390,AI122807„20,192,TGAGCATAGCATTTAATTGT„

4391 ,AI122807„20, 186,TAGCATTTAATTGTTGATGC„

4392,AI122807„20,180,TTAATTGTTGATGCAAGACC„

4393,AI122807„20,174,GTTGATGCAAGACCTTCCAG„ 4394,AI122807„20,168,GCAAGACCTTCCAGAACTCT„

4395,AI122807„20,162,CCTTCCAGAACTCTTTTTCT„

4396,AI122807„20,156,AGAACTCTTTTTCTCTTTGC„

4397,AI122807„20,150,CTTTTTCTCTTTGCCATGGC„

4398,AI122807„20,144,CTCTTTGCCATGGCAATCAT„ 4399,AI122807„20,138,GCCATGGCAATCATCAGTGT„

4400,AI122807„20,132,GCAATCATCAGTGTTCCAGA„

4401,AI122807„20,126,ATCAGTGTTCCAGAGAGCAT„

4402,AI122807„20,120,GTTCCAGAGAGCATATGCAC„

4403,AI122807„20,114,GAGAGCATATGCACGATCAG„ 4404,AI122807„20,108,ATATGCACGATCAGCCTTGG„

4405,AI122807„20,102,ACGATCAGCCTTGGTATTGG„

4406,AI122807„20,96,AGCCTTGGTATTGGAGGGAA„

4407,AI122807„20,90,GGTATTGGAGGGAAGATGAT„

4408,AI122807„20,84,GGAGGGAAGATGATGCGGAA„ 4409,AI122807„20,78,AAGATGATGCGGAACAGAGT„

4410,AI122807„20,72,ATGCGGAACAGAGTCCCAGT„

4411,AI122807„20,66,AACAGAGTCCCAGTCACATC„

4412,AI122807„20,60,GTCCCAGTCACATCATGAAG„

4413,AI122807„20,54,GTCACATCATGAAGGACATG„ 4414,AI122807„20,48,TCATGAAGGACATGTAAAGT„

4415,AI122807„20,42,AGGACATGTAAAGTGAGAAG„

4416,AI122807„20,36,TGTAAAGTGAGAAGTAAACC„

4417,AI122807„20,30,GTGAGAAGTAAACCTTGGTT„

4418,AI122807„20,24,AGTAAACCTTGGTTGTTTTA„ 4419,AI122807„20,18,CCTTGGTTGTTTTAAAAAAA„

4420,AI122807„20,12,TTGTTTTAAAAAAAAAAAAA„

4421,AI122807„20,6,TAAAAAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. AI041212) GTCTTCTCAATGTTAAAAATAATTTTTTTCTACCATGTAAAACCTAGCCTTCTCTTTGACTTTTGAAAATTATATTTTGGTCCCTGAGA GTTATAAAAAGGGAGCTGGACTCCAGTAACATCATTTGCCTGATAGCTGGGTCTTAATCCACCTTTGTCCACAAACACTGGTCCACG GCCACCTCCAGGTCCTTCCTGTACAGCTTTTACAAGAGGGTAAATATATTTATTTGGTGTTTCCGATTCAAGTTCAATTACCTCTCTG GCATAGTCCTGAAATTCTTTCTCCTTT (SEQ ID NO: 4422)

4423,AI041212„20,362,AAAGGAGAAAGAATTTCAGG„

4424,AI041212„20,356,GAAAGAATTTCAGGACTATG„

4425,AI041212„20,350,ATTTCAGGACTATGCCAGAG„

4426,AI041212„20,344,GGACTATGCCAGAGAGGTAA„ 4427,AI041212„20,338,TGCCAGAGAGGTAATTGAAC„

4428,AI041212„20,332,AGAGGTAATTGAACTTGAAT„

4429,AI041212„20,326_>AATTGAACTTGAATCGGAAA„

4430,AI041212„20,320,ACTTGAATCGGAAACACCAA„

4431,AI041212„20,314,ATCGGAAACACCAAATAAAT„ 4432,AI041212„20,308,AACACCAAATAAATATATTT„

4433,AI041212„20,302_>AAATAAATATATTTACCCTC„

4434,AI041212„20,296,ATATATTTACCCTCTTGTAA„

4435,AI041212„20,290,TTACCCTCTTGTAAAAGCTG„

4436,AI041212„20,284,TCTTGTAAAAGCTGTACAGG„ 4437,AI041212„20,278,AAAAGCTGTACAGGAAGGAC„

4438,AI041212„20,272,TGTACAGGAAGGACCTGGAG„

4439,AI041212„20,266,GGAAGGACCTGGAGGTGGCC„

4440,AI041212„20,260,ACCTGGAGGTGGCCGTGGAC„

4441,AI041212„20,254,AGGTGGCCGTGGACCAGTGT„ 4442,AI041212„20,248,CCGTGGACCAGTGTTTGTGG„

4443,AI041212„20,242,ACCAGTGTTTGTGGACAAAG„

4444,AI041212„20,236,GTTTGTGGACAAAGGTGGAT„

4445,AI041212„20,230_SGGACAAAGGTGGATTAAGAC„

4446,AI041212„20,224,AGGTGGATTAAGACCCAGCT„ 4447,AI041212„20,218,ATTAAGACCCAGCTATCAGG„

4448,AI041212„20,212,ACCCAGCTATCAGGCAAATG„

4449,AI041212„20,206,CTATCAGGCAAATGATGTTA„

4450,AI041212„20,200,GGCAAATGATGTTACTGGAG„

4451 ,AI041212„20, 194,TGATGTTACTGGAGTCCAGC„ 4452,AI041212„20,188,TACTGGAGTCCAGCTCCCTT„

4453,AI041212„20,182,AGTCCAGCTCCCTTTTTATA„

4454,AI041212„20,176_JGCTCCCTTTTTATAACTCTC„

4455,AI041212„20,170,TTTTTATAACTCTCAGGGAC„

4456,AI041212„20,164,TAACTCTCAGGGACCAAAAT„ 4457,AI041212„20,158,TCAGGGACCAAAATATAATT„

4458,AI041212„20,152,ACCAAAATATAATTTTCAAA„

4459,AI041212„20,146,ATATAATTTTCAAAAGTCAA„

4460,AI041212„20,140,TTTTCAAAAGTCAAAGAGAA„

4461 ,AI041212„20, 134,AAAGTCAAAGAGAAGGCTAG„ 4462,AI041212„20,128,AAAGAGAAGGCTAGGTTTTA„

4463.AI041212„20, 122,AAGGCTAGGTTTTACATGGT„

4464,AI041212„20,116,AGGTTTTACATGGTAGAAAA„

4465,AI041212,,20,110,TACATGGTAGAAAAAAATTA„

4466,AI041212„20,104,GTAGAAAAAAATTATTTTTA„ 4467.AI041212„20,98,AAAAATTATTTTTAACATTG„

4468,AI041212„20,92,TATTTTTAACATTGAGAAGA„

4469,AI041212„20,86,TAACATTGAGAAGACTAAGT„

4470,AI041212„20,80,TGAGAAGACTAAGTTGTAGC„

4471,AI041212„20,74,GACTAAGTTGTAGCATATAT„ 4472,AI041212„20,68,GTTGTAGCATATATGAGCTT„

4473,AI041212„20,62,GCATATATGAGCTTCAAATA„

4474.AI041212„20,56,ATGAGCTTCAAATATAAATG„

4475,AI041212„20,50,TTCAAATATAAATGGATTTC„

4476,AI041212„20,44,TATAAATGGATTTCAGTTAA„ 4477,AI041212„20,38,TGGATTTCAGTTAATAAAGC„

4478,AI041212„20,32,TCAGTTAATAAAGCTGTTCT„

4479,AI041212„20,26,AATAAAGCTGTTCTTCATCT„

4480,AI041212„20,20,GCTGTTCTTCATCTAAAAAA„

4481,AI041212„20,14,CTTCATCTAAAAAAAAAAAA„ 4482,AI041212„20,8,CTAAAAAAAAAAAAAAAAAA„

4483,AI041212„20,2,AAAAAAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. AI125651) _{τττττττττττττττττπ}^

ATGACGACTTTGGACATTGCTAGGTAATTGTCAAAATTGTGCATTTGAACAGCAGCAAAATATTCAAAGCTGGTGTGCCCTCGCTGA CACGAAATGAATTGTCATTTTCTGAACATTCACCAAAGCCTGCCAGGCGCTAGGCCTAGGTTCAGCAGCACACAATAGTGAAGCCC

CCATTCAAGCGGGCTTCGTTTCACCAGCGTACGTCACACGTCCGTGGAGCAGCGAGACCAGAGGAGCTGGGAAAGCCAGGGCTGAG CCTTGTGCTTTTGCCCTTTTAAGGGAGGA (SEQ ID NO: 4484) 4485,AI125651„20,358,TCCTCCCTTAAAAGGGCAAA„ 4486,AI125651„20,352,CTTAAAAGGGCAAAAGCACA„

4487,AI125651„20,346,AGGGCAAAAGCACAAGGCTC„

4488,AI125651„20,340,AAAGCACAAGGCTCAGCCCT„

4489,AI125651,,20,334,CAAGGCTCAGCCCTGGCTTT„ 4490,AI125651„20,328,TCAGCCCTGGCTTTCCCAGC„

4491,AI125651,,20,322,CTGGCTTTCCCAGCTCCTCT„

4492,AI125651„20,316,TTCCCAGCTCCTCTGGTCTC„

4493,AI125651„20,310,GCTCCTCTGGTCTCGCTGCT„

4494,AI12₅651„2O,304,CTGGTCTCGCTGCTCCACGG„ 4495,AI12₅651„20,298,TCGCTGCTCCACGGACGTGT„

4496,AI12₅651„20,292,CTCCACGGACGTGTGACGTA„

4497,AI12₅651„20,286,GGACGTGTGACGTACGCTGG„

4498,AI125651„20,280,GTGACGTACGCTGGTGAAAC„

4499,AI125651 „20,274,TACGCTGGTGAAACGAAGCC„ 4500,AH25651„20,268,GGTGAAACGAAGCCCGCTTG„

4501.AI125651 „20,262,ACGAAGCCCGCTTGAATGGG„

4502,AI125651„20,256,CCCGCTTGAATGGGGGCTTC„

4503,AI125651„20,250,TGAATGGGGGCTTCACTATT„

4504,AI125651„20,244,GGGGCTTCACTATTGTGTGC„ 4505,AI125651„20,238,TCACTATTGTGTGCTGCTGA„

4506,AI125651,,20,232,TTGTGTGCTGCTGAACCTAG„

4507,AI125651„20,226,GCTGCTGAACCTAGGCCTAG„

4508,AI125651„20,220,GAACCTAGGCCTAGCGCCTG„

4509,AI125651„20,214,AGGCCTAGCGCCTGGCAGGC„ 4510,AI125651„20,208,AGCGCCTGGCAGGCTTTGGT„

4511,AI125651„2O,202,TGGCAGGCTTTGGTGAATGT„

4512,AI125651„20,196,GCTTTGGTGAATGTTCAGAA„

45f3,AI125651„2O,190,GTGAATGTTCAGAAAATGAC„

4514,AI125651„20,184,GTTCAGAAAATGACAATTCA„ 4515,AI125651„20,178,AAAATGACAATTCATTTCGT„

4516,AI125651„20,172,ACAATTCATTTCGTGTCAGC„

4517,AI125651„20,166,CATTTCGTGTCAGCGAGGGC„

4518,AI125651„20,160,GTGTCAGCGAGGGCACACCA„

4519,AI125651„20,154,GCGAGGGCACACCAGCTTTG„ 4520,AI125651„20,148,GCACACCAGCTTTGAATATT„

452I,AI125651„20,142,CAGCTTTGAATATTTTGCTG„

4522,AI125651„20,136,TGAATATTTTGCTGCTGTTC„

4523,AI125651„20,I30,TTTTGCTGCTGTTCAAATGC„

4524,AI12₅651„20,I24,TGCTGTTCAAATGCACAATT„ 4525,AI125651„20,l 18,TCAAATGCACAATTTTGACA„

4526,AI12₅651„20,I12,GCACAATTTTGACAATTACC„

4₅27,AI12₅651„2O,I06,TTTTGACAATTACCTAGCAA„

4528,AI12₅651„2O,10O,CAATTACCTAGCAATGTCCA„

4529,AI125651„20,94,CCTAGCAATGTCCAAAGTCG„ 4530,AI125651„20,88,AATGTCCAAAGTCGTCATAA„

4531,AI125651 „20,82,CAAAGTCGTCATAATTGTTA„

4532,AI125651,,20,76,CGTCATAATTGTTAGTGTCT„

4533,AI125651„20,70,AATTGTTAGTGTCTTGCACG„

4534,AI125651„20,64,TAGTGTCTTGCACGTGATGT„ 4535,AI125651„20,58,CTTGCACGTGATGTTCCTTA„

4536,AI125651„20,52,CGTGATGTTCCTTATAACCA„

4537,AI125651„20,46,GTTCCTTATAACCATGTAAT„

4538,AI125651„2O,40,TATAACCATGTAATAAATAC„

4539,AI125651„20,34,CATGTAATAAATACAGTGTG„ 4540,AI125651 „20,28,ATAAATACAGTGTGAAGTCT„

4541,AI125651„20,22,ACAGTGTGAAGTCTCAAAAA„

4542,AI125651„20,16,TGAAGTCTCAAAAAAAAAAA„

4543.AI125651 „20,10,CTCAAAAAAAAAAAAAAAAA„

4544,AI125651„20,4,AAAAAAAAAAAAAAAAAAAA„ (GENBANK ACCESSION NO. AI001174)

TCATGGGTCACTGAGGCTTTTTATTTTGAGCACAAAACCACCGGGGATCTAGCCTGTGGCACCCCGGAGATGACACGAGGCTCACAT

GACTCTAGACACTTGGTGGAAAGTGAGGCGAGAAAAACAATGACTTGGGCCAATTACACGACTGCAAAGCTAGAGCTGCCAACAG

GGCTCCAGGGAGCTTGGCTTCTGTAGAAGTTCTGTGACGTTCAGTTTCTTGCTAACCAGGGCAGGCGCAATAGTTTTATTGATGTGCT

CAACAGCCTTTGAGACACCCTTCCCCATATATGCGAGTCTTATCATTGTCCCGGAGCTCTAGGGCCTCATAGATACCAGTTTGAAGC ACCACTGGGCACAGCAGCTCTGAAGAGACCTTTTCAGGTGAACAGATCAACCTCAACAGTGGGATTCCCGCGAGAGTCCAAGATCT

CCCGGCATGGATCTCGAGAATAGACATGGTGAACTTTCAGCCACTGGGTCTCGTCGCCTAGAGAGGAAGCGGAGTGTGCTTCAGAC

AC

(SEQ ID NO: 4545) 4546,AI001174„20,502,GTGTCTGAAGCACACTCCGC„

4547.AI001174,,20,496,GAAGCACACTCCGCTTCCTC„ 4548,AI001174„20,490,CACTCCGCTTCCTCTCTAGG„ 4549.AI001174₎,20,484,GCTTCCTCTCTAGGCGACGA„ 4550,AI001174,,20,478,TCTCTAGGCGACGAGACCCA„ 4₅₅1,AI001174„20,472,GGCGACGAGACCCAGTGGCT„ 4552,AI001174„20,466,GAGACCCAGTGGCTGAAAGT„ 4553,AI001174„20,460,CAGTGGCTGAAAGTTCACCA„ 4554,AI001174„20,454,CTGAAAGTTCACCATGTCTA„ 4555,AI001174„20,448,GTTCACCATGTCTATTCTCG„ 4556.AI001174„20,442,CATGTCTATTCTCGAGATCC„

4557,AI001174„20,436,TATTCTCGAGATCCATGCCG„ 4558,AI001174„20,430_;CGAGATCCATGCCGGGAGAT„ 45₅9,AI001174„20,424,CCATGCCGGGAGATCTTGGA„ 4560,AI001174„20,418,CGGGAGATCTTGGACTCTCG„ 4561.AI001174„20,412,ATCTTGGACTCTCGCGGGAA„

4562,AI001174„20,406,GACTCTCGCGGGAATCCCAC„ 4563,AI001174„20,400,CGCGGGAATCCCACTGTTGA„ 4564,AI001174„20,394,AATCCCACTGTTGAGGTTGA„ 4565,AI001174„20,388,ACTGTTGAGGTTGATCTGTT„ 4566,AI001174„20,382,GAGGTTGATCTGTTCACCTG„

4567,AI001174„20,376,GATCTGTTCACCTGAAAAGG„ 4568,AI001174„20,370,TTCACCTGAAAAGGTCTCTT„ 4569,AI001174„20,364,TGAAAAGGTCTCTTCAGAGC„ 4570,AI001174„20,358,GGTCTCTTCAGAGCTGCTGT„ 4571.AI001174„20,352,TTCAGAGCTGCTGTGCCCAG„

4572,AI001174„20,346,GCTGCTGTGCCCAGTGGTGC„ 4573,AI001174„20,340,GTGCCCAGTGGTGCTTCAAA„ 4574,AI001174„20,334,AGTGGTGCTTCAAACTGGTA„ 4575,AI001174„20,328,GCTTCAAACTGGTATCTATG„ 4576,AI001174„20,322,AACTGGTATCTATGAGGCCC„

4577,AI001174„20,316,TATCTATGAGGCCCTAGAGC„ 4₅78,AI001174„20,310_STGAGGCCCTAGAGCTCCGGG„ 4579.AI001174„20,304,CCTAGAGCTCCGGGACAATG„ 4580,AI001174„20,298,GCTCCGGGACAATGATAAGA„ 4581 ,AI001174„20,292,GGACAATGATAAGACTCGCA„

4582,AI001174„20,286,TGATAAGACTCGCATATATG„ 4583,AI001174„20,280,GACTCGCATATATGGGGAAG„ 4584,AI001174„20,274,CATATATGGGGAAGGGTGTC„ 4585,AI001174„20,268,TGGGGAAGGGTGTCTCAAAG„ 4586,AI001174„20,262,AGGGTGTCTCAAAGGCTGTT„

4587,AI001174„20,256,TCTCAAAGGCTGTTGAGCAC„ 4588,AI001174„20,250,AGGCTGTTGAGCACATCAAT„ 4589,AI001 I74„20,244,TTGAGCACATCAATAAAACT„ 4590,AI001174„20,238,ACATCAATAAAACTATTGCG„ 4591.AI001174„20,232,ATAAAACTATTGCGCCTGCC„

4592,AI001174„20,226,CTATTGCGCCTGCCCTGGTT„ 4593,AI001174„20,220,CGCCTGCCCTGGTTAGCAAG„ 4594,AI001174„20,214,CCCTGGTTAGCAAGAAACTG„ 4595,AI001174„20,208,TTAGCAAGAAACTGAACGTC„ 4596.AI001174„20,202,AGAAACTGAACGTCACAGAA„

4597,AI001174„20,196,TGAACGTCACAGAACTTCTA„ 4598,AI001174„20, 190,TCACAGAACTTCTACAGAAG„ 4599,AI001174„20,184,AACTTCTACAGAAGCCAAGC„ 4600,AI001174„20,178,TACAGAAGCCAAGCTCCCTG„ 4601.AI001174„20,172,AGCCAAGCTCCCTGGAGCCC„

4602,AI001174„20,166,GCTCCCTGGAGCCCTGTTGG„ 4603,AI001174„20,160,TGGAGCCCTGTTGGCAGCTC„ 4604.AIOO 1174„20, 154,CCTGTTGGCAGCTCTAGCTT„ 4605.AI001174„20, 148,GGCAGCTCTAGCTTTGCAGT„ 4606.AI001174„20,142,TCTAGCTTTGCAGTCGTGTA„

4607,AI001174„20,136,TTTGCAGTCGTGTAATTGGC„ 4608,AI001174„20, 130,GTCGTGTAATTGGCCCAAGT„ 4609,AI001174„20,124,TAATTGGCCCAAGTCATTGT„ 4610.AI001174„20, 118.GCCCAAGTCATTGTTTTTCT,, 4611,AI001174„20,112,GTCATTGTTTTTCTCGCCTC„

4612,AI001174„20,106,GTTTTTCTCGCCTCACTTTC„ 4613,AI001174„20,100,CTCGCCTCACTTTCCACCAA„ 4614,AI001174„20,94,TCACTTTCCACCAAGTGTCT„ 4615,AI001174„20,88,TCCACCAAGTGTCTAGAGTC„ 4616,AI001174„20,82,AAGTGTCTAGAGTCATGTGA„

4617,AI001174„20,76,CTAGAGTCATGTGAGCCTCG„ 4618,AI001174„20,70,TCATGTGAGCCTCGTGTCAT„ 4619.AI001174„20,64,GAGCCTCGTGTCATCTCCGG„ 4620,AI001174„20,58,CGTGTCATCTCCGGGGTGCC„ 4621 ,AI001174„20,52,ATCTCCGGGGTGCCACAGGC„

4622,AI001174„20,46,GGGGTGCCACAGGCTAGATC„ 4623,AI001174„20,40,CCACAGGCTAGATCCCCGGT„ 4624.AI001174„20,34,GCTAGATCCCCGGTGGTTTT„ 4625,AI001174„20,28,TCCCCGGTGGTTTTGTGCTC„ 4626,AI001174„20,22,GTGGTTTTGTGCTCAAAATA„ 4627,AI001174„20,16,TTGTGCTCAAAATAAAAAGC„

4628,AI001174„20,10,TCAAAATAAAAAGCCTCAGT„

4629,AI001174„20,4,TAAAAAGCCTCAGTGACCCA„

(GENBANK ACCESSION NO. AI024215) _{ττττττττττττττττπ}^

GATGTGTAGGTATTGGGCTTTCTCGTGGACACTGAAATTCCATTCATTGAACAACACCTTATTTCCTGTATAGAGAATGGTGCTAGG GGCCAGCGTCAAATTTGAAGATGAAGTCTGACTGAAGGTCATCGTTTGGAGTTGGGGTGGGGTGAAGAGTAGACAAACTCGGCCAG AGTGATCGGAGTTGGCGGCTGTCTGGGGGAGTTGGGTCAGGAAGCCCCTTCTTTCGCCACCGATGGGGCACGTC (SEQ ID NO: 4630)

4631 ,AI0242 \ ₅„₂o,318,GACGTGCCCCATCGGTGGCG„

4632,AI024215„20,312,CCCCATCGGTGGCGAAAGAA„

4633,AI024215„20,306,CGGTGGCGAAAGAAGGGGCT„

4634,AI024215„20,300,CGAAAGAAGGGGCTTCCTGA„

463₅,AI024215„20,294,AAGGGGCTTCCTGACCCAAC„

4636,AI024215„20,288,CTTCCTGACCCAACTCCCCC„

4637.AI024215„20,282,GACCCAACTCCCCCAGACAG„

4638,AI024215„20,276,ACTCCCCCAGACAGCCGCCA„

4639.AI024215„20,270,CCAGACAGCCGCCAACTCCG„

4640,AI024215„20,264,AGCCGCCAACTCCGATCACT„

4641,AI024215„20,258,CAACTCCGATCACTCTGGCC„

4642,AI024215„20,252,CGATCACTCTGGCCGAGTTT„

4643,AI024215„20,246,CTCTGGCCGAGTTTGTCTAC„

4644.AI024215„20,240,CCGAGTTTGTCTACTCTTCA„

4645,AI024215„20,234,TTGTCTACTCTTCACCCCAC„

4646,AI024215„20,228,ACTCTTCACCCCACCCCAAC„

4647,AI024215„20,222,CACCCCACCCCAACTCCAAA„

4648.AI024215„20,216,ACCCCAACTCCAAACGATGA„

4649.AI024215„20,210,ACTCCAAACGATGACCTTCA„

4650.AI024215„20,204,AACGATGACCTTCAGTCAGA„

4651.AI024215„20, 198,GACCTTCAGTCAGACTTCAT„

4652.AI024215„20, 192,CAGTCAGACTTCATCTTCAA„

4653,AI024215„20,186,GACTTCATCTTCAAATTTGA„

4654,AI024215„20, 180,ATCTTCAAATTTGACGCTGG„

4655.AI024215„20, 174,AAATTTGACGCTGGCCCCTA„

4656,AI024215„20, 168,GACGCTGGCCCCTAGCACCA„

4657,AI024215„20, 162,GGCCCCTAGCACCATTCTCT„

4658 I024215„20, 156,TAGCACCATTCTCTATACAG„

46₅9,AI02421₅„20, 1₅0,CATTCTCTATACAGGAAATA„

4660,AI02421₅„20, 144,CTATACAGGAAATAAGGTGT„

4661 ,AI02421₅„20, 138,AGGAAATAAGGTGTTGTTCA„

4662,AI02421₅„20, 132,TAAGGTGTTGTTCAATGAAT„

4663,AI024215„20,126,GTTGTTCAATGAATGGAATT„

4664,AI024215„20, 120,CAATGAATGGAATTTCAGTG„

4665,AI024215„20,114,ATGGAATTTCAGTGTCCACG„

4666,AI024215„20,108,TTTCAGTGTCCACGAGAAAG„

4667.AI024215„20, 102,TGTCCACGAGAAAGCCCAAT„ '

4668.AI024215„20,96,CGAGAAAGCCCAATACCTAC„

4669,AI024215„20,90,AGCCCAATACCTACACATCC„

4670,AI024215„20,84,ATACCTACACATCCAATTCC„

4671 ,AI024215„20,78 ,ACACATCCAATTCCCATTAT„

4672.AI024215„20,72,CCAATTCCCATTATCAAATG„

4673,AI02421₅„20,66,CCCATTATCAAATGTTTGCA„

4674,AI024215„20,60,ATCAAATGTTTGCACAAGAA„

4675,AI024215„20,54,TGTTTGCACAAGAATCGCAA„

4676,AI024215„20,48,CACAAGAATCGCAAATTAAA„

4677ΛI024215„20,42,AATCGCAAATTAAAGCCACC„

4678.AI024215„20,36,AAATTAAAGCCACCACTTCA„

4679,AI02421₅„20,30,AAGCCACCACTTCATCAACT„

4680.AI024215„20,24,CCACTTCATCAACTGGTCAA„

4681 I024215„20, 18,CATCAACTGGTCAAAAAAAA„

4682.AI024215„20, 12,CTGGTCAAAAAAAAAAAAAA„

4683.AI024215„20,6,AAAAAAAAAAAAAAAAAAAA„ _τ (G_τE_τN_τB_τA_ττN_τK_τ A_ττC_τC_χE_τS_τS_τIO_τN_τG N_GO_T._T A_GI0_π34^360)

TGTCTCAGGCTAGATTTGGTATTGTATAAGTAAGCTTTGTGTTAGAGGATGATAAGAATAAATTTAAAATTTTAATTGAACAATTCC AGGCACCAGAGGCAAACTTAAAGCTTAAAATGCTAAATAAAGCCAGCTGCCAAAAAGGCCAAGCTGGTGGTTACAGCTGTTTACCA TCATGCAACAAAAATATAAAATCT (SEQ ID NO: 4684)

4685,AI034360„20,267,AGATTTTATATTTTTGTTGC„

4686,AI034360„20,261,TATATTTTTGTTGCATGATG„

4687,AI034360„20,2₅₅,TTTGTTGCATGATGGTAAAC„

4688,AI034360„20,249,GCATGATGGTAAACAGCTGT„

4689,AI034360„20,243,TGGTAAACAGCTGTAACCAC„ 4690,AI034360„20,237,ACAGCTGTAACCACCAGCTT„

4691,AI034360„20,231,GTAACCACCAGCTTGGCCTT„

4692,AI034360„20,225,ACCAGCTTGGCCTTTTTGGC„

4693,AI034360„20,219,TTGGCCTTTTTGGCAGCTGG„ 4694,AI034360„20,213,TTTTTGGCAGCTGGCTTTAT„

4695,AI034360„20,207,GCAGCTGGCTTTATTTAGCA„

4696,AI034360„20,201,GGCTTTATTTAGCATTTTAA„

4697,AI034360„20, 195,ATTTAGCATTTTAAGCTTTA„

4698,AI034360„20,189,CATTTTAAGCTTTAAGTTTG„ 4699,AI034360„20,183,AAGCTTTAAGTTTGCCTCTG„

4700,AI034360„20,177,TAAGTTTGCCTCTGGTGCCT„

4701 ,AI034360„20, 171 ,TGCCTCTGGTGCCTGGAATT„

4702,AI034360„20,165,TGGTGCCTGGAATTGTTCAA„

4703,AI034360„20,159,CTGGAATTGTTCAATTAAAA„ 4704,AI034360„20,153,TTGTTCAATTAAAATTTTAA„

4705,AI034360„20,147,AATTAAAATTTTAAATTTAT„

4706,AI034360„20,141,AATTTTAAATTTATTCTTAT„ 9

4707,AI034360„20,135,AAATTTATTCTTATCATCCT„

4708,AI034360„20,129,ATTCTTATCATCCTCTAACA„ 4709,AI034360„20,123,ATCATCCTCTAACACAAAGC„

4710,AI034360„20,117,CTCTAACACAAAGCTTACTT„

4711,AI034360„20,11 l.CACAAAGCTTACTTATACAA,,

4712,AI034360„20,105,GCTTACTTATACAATACCAA„

4713,AI034360„20,99,TTATACAATACCAAATCTAG„ 4714,AI034360„20,93,AATACCAAATCTAGCCTGAG„

4715,AI034360„20,87,AAATCTAGCCTGAGACACTT„

4716,AI034360„20,81 ,AGCCTGAGACACTTGTTCTT„

4717,AI034360„20,75,AGACACTTGTTCTTGAATCG„

4718,AI034360„20,69,TTGTTCTTGAATCGATTCTT„ 4719,AI034360„20,63,TTGAATCGATTCTTTTTTAA„

4720,AI034360„20,57,CGATTCTTTTTTAAATAATA„

4721 ,AI034360„20,51 ,TTTTTTAAATAATAAGTTCA„

4722,AI034360„20,45,AAATAATAAGTTCAATATGA„

4723,AI034360„20,39,TAAGTTCAATATGAAATAAA„ 4724,AI034360„20,33,CAATATGAAATAAATCTATT„

4725,AI034360„20,27,GAAATAAATCTATTCTGCTA„

4726,AI034360„20,21,AATCTATTCTGCTACAACAA„

4727,AI034360„20,15,TTCTGCTACAACAACCAAAA„

4728,AI034360„20,9,TACAACAACCAAAAAAAAAA„ 4729,AI034360„20,3,AACCAAAAAAAAAAAAAAAA„ _τ (G_τE_τN_τB_τA_τπNK_τ A_ττC_τC_τE_τS_τS_τIO_τN_ττ N_τO_τ._τ A_TA_A4_A6_A5_A68_T7_T)_{TCAGATGTTTTTTATT}

TCAAATGTACAGTTCAAAAATGTCTTTTGGCGTTTAACAACAAGTCCTAGGAAAGAAAACTACAGAGTTATCTTGAACCGGACAAA TAAGTTACCACTGGCAAGTCTGTGGCACTAGTAAAACAAAAATAAAAAATTAACTCTCTTGATCATATAGATATCTCTATGAAAATC TTTTTTTTTCAATCTGTACAAAAGGTCTTTCTTCATAAATTAATTTTTTTATAATTTAATGGCTGTCTACTATGTGATGTTTAACTGATT

TTTTTTTTTTTATGT (SEQ ID NO: 4730)

4731,AA465687„20,348,ACATAAAAAAAAAAAAATCA„ 4732,AA465687„20,342,AAAAAAAAAAATCAGTTAAA„

4733,AA465687„20,336,AAAAATCAGTTAAACATCAC„

4734,AA465687„20,330,CAGTTAAACATCACATAGTA„

4735,AA465687„20,324,AACATCACATAGTAGACAGC„

4736,AA465687„20,31 S,ACATAGTAGACAGCCATTAA„ 4737,AA465687„20,312,TAGACAGCCATTAAATTATA„

4738,AA465687„20,306,GCCATTAAATTATAAAAAAA„

4739,AA465687„20,300,AAATTATAAAAAAATTAATT„

4740,AA465687„20,294,TAAAAAAATTAATTTATGAA„

4741,AA465687„20,288,AATTAATTTATGAAGAAAGA„ 4742,AA465687„20,282,TTTATGAAGAAAGACCTTTT„

4743,AA465687„20,276,AAGAAAGACCTTTTGTACAG„

4744,AA46₅687„20,270,GACCTTTTGTACAGATTGAA„

4745,AA465687„20,264,TTGTACAGATTGAAAAAAAA„

4746,AA465687„20,258,AGATTGAAAAAAAAAGATTT„ 4747,AA465687„20,252,AAAAAAAAAGATTTTCATAG„

4748,AA465687„20,246,AAAGATTTTCATAGAGATAT„

4749,AA465687„20,240,TTTCATAGAGATATCTATAT„

4750,AA465687„20,234,AGAGATATCTATATGATCAA„

4751,AA465687„20,228,ATCTATATGATCAAGAGAGT„ 4752,AA465687„20,222,ATGATCAAGAGAGTTAATTT„

4753,AA465687„20,216,AAGAGAGTTAATTTTTTATT„

4754,AA465687„20,210,GTTAATTTTTTATTTTTGTT„

47₅5,AA465687„20,204,TTTTTATTTTTGTTTTACTA„

4756,AA46₅687„20,198,TTTTTGTTTTACTAGTGCCA„ 4757,AA465687„20,192,TTTTACTAGTGCCACAGACT„ 4758,AA465687„20,186,TAGTGCCACAGACTTGCCAG„

4759,AA465687„20,180,CACAGACTTGCCAGTGGTAA„

4760,AA465687„20,174,CTTGCCAGTGGTAACTTATT„

4761,AA465687„20,168,AGTGGTAACTTATTTGTCCG„ 4762,AA465687„20, 162,AACTTATTTGTCCGGTTCAA„

4763,AA465687„20,156,TTTGTCCGGTTCAAGATAAC„

4764,AA465687„20, 150,CGGTTCAAGATAACTCTGTA„

4765,AA465687„20,144,AAGATAACTCTGTAGTTTTC„

4766,AA465687„20,138,ACTCTGTAGTTTTCTTTCCT„ 4767,AA465687„20, 132,TAGTTTTCTTTCCTAGGACT„

4768,AA465687„20,126,TCTTTCCTAGGACTTGTTGT„

4769,AA465687„20, 120,CTAGGACTTGTTGTTAAACG„

4770,AA465687„20,114,CTTGTTGTTAAACGCCAAAA„

4771 ,AA465687„20, 108,GTTAAACGCCAAAAGACATT„ 4772,AA465687„20,102,CGCCAAAAGACATTTTTGAA„

4773,AA465687„20,96,AAGACATTTTTGAACTGTAC„

4774,AA465687,,20,90,TTTTTGAACTGTACATTTGA„

4775,AA465687„20,84,AACTGTACATTTGATCAGAT„

4776,AA465687„20,78,ACATTTGATCAGATTGTTAG„ 4777,AA4656S7„20,72,GATCAGATTGTTAGCTTTTC„

4778,AA465687„20,66,ATTGTTAGCTTTTCTGTTTT„

4779,AA465687„20,60,AGCTTTTCTGTTTTATTTCT„

4780,AA465687„20,₅4,TCTGTTTTATTTCTTTTGAG„

4781 ,AA465687„20,48,TTATTTCTTTTGAGAACCTT„ 4782,AA465687„20,42,CTTTTGAGAACCTTTGAATA„

4783,AA465687„20,36,AGAACCTTTGAATAAAAAAC„

4784,AA465687„20,30 TTGAATAAAAAACATCTGA„

4785,AA465687„20,24,TAAAAAACATCTGAAATTTT„

4786,AA465687„20,18,ACATCTGAAATTTTAAAAAA„ 4787,AA465687„20,12,GAAATTTTAAAAAAAAAAAA„

4788,AA465687„20,6,TTAAAAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. AI085559)

TCGAGACAGACAACCTCAAAATAAGGTCCAAATATTGGTTCCTTCAAATGGTGTCAAAAAGAATAGTATTATATGAGGAGGATAGT

TATCACAGAATAAGAACTAAAATCCCATTTTTTTTTTTTAGGAAAAAAAGACCTTCGATGATGCAGGTGTCTGTGTATAAGGAACTA TGACCTACCAAAAAAACCACCACATAAGGAGAGGCCAATATAATTTGCCAGTCTGACAAGACAGTTGGTATTATAAGTGGAAGAGA

CTTCAAGGATCACATAATTCAGCTCTTTGATTTTAGAGGGAGGAAAGACGAGGCCCAGAGATGGGAAGTGGCTTGCCTAAGTACAT

TAGCAAGTTAGCTTCAATGGTTATTTTTATACACACACAGGCACACATACATACTG

(SEQ ID NO: 4789) 4790,AI085559„20,382,CAGTATGTATGTGTGCCTGT„

4791,AI085559„20,376,GTATGTGTGCCTGTGTGTGT„

4792,AI085559„20,370,GTGCCTGTGTGTGTATAAAA„

4793,AI085559„20,364,GTGTGTGTATAAAAATAACC„

4794,AI085559„20,358,GTATAAAAATAACCATTGAA„ 4795,AI085559„20,352,AAATAACCATTGAAGCTAAC„

4796,AI085559„20,346,CCATTGAAGCTAACTTGCTA„

4797,AI085559„20,340,AAGCTAACTTGCTAATGTAC„

4798,AI085559„20,334,ACTTGCTAATGTACTTAGGC„

4799,AI08₅559„20,328,TAATGTACTTAGGCAAGCCA„ 4800,AI085559„20,322,ACTTAGGCAAGCCACTTCCC„

4801,AI085559„20,316.GCAAGCCACTTCCCATCTCT,,

4802,AI085559„20,310.CACTTCCCATCTCTGGGCCT,,

4803,AI085559„20,304_>CCATCTCTGGGCCTCGTCTT„

4804,AI085559„20,298,CTGGGCCTCGTCTTTCCTCC„ 4805,AI085559„20,292,CTCGTCTTTCCTCCCTCTAA„

4806,AI085559„20,286 TTCCTCCCTCTAAAATCAA„

4807,AI085559„20,280,CCCTCTAAAATCAAAGAGCT„

4808,AI085559„20,274,AAAATCAAAGAGCTGAATTA„

4809,AI085559„20,268,AAAGAGCTGAATTATGTGAT„ 4810,AI085559„20,262,CTGAATTATGTGATCCTTGA„

4811,AI085559„20,256 ATGTGATCCTTGAAGTCTC„

4812,AI085559„20,250,ATCCTTGAAGTCTCTTCCAC„

4813,AI08₅559„20,244,GAAGTCTCTTCCACTTATAA„

4814,AI085559„20,238,TCTTCCACTTATAATACCAA„ 4815,AI085559„20,232,ACTTATAATACCAACTGTCT„

4816,AI085559„20,226,AATACCAACTGTCTTGTCAG„

4817,AI085559„20,220,AACTGTCTTGTCAGACTGGC„

4818,AI085559„20,214,CTTGTCAGACTGGCAAATTA„

4819,AI085559„20,208,AGACTGGCAAATTATATTGG„ 4820,AI085559„20,202,GCAAATTATATTGGCCTCTC„

4821,AI085559„20,196,TATATTGGCCTCTCCTTATG„

4822,AI085559„20, 190,GGCCTCTCCTTATGTGGTGG„

4823,AI085559„20,184,TCCTTATGTGGTGGTTTTTT„

4824,AI085559„20,178,TGTGGTGGTTTTTTTGGTAG„ 4825,AI085₅59„20,172,GGTTTTTTTGGTAGGTCATA„ 4826,AI085559„20, 166,TTTGGTAGGTCATAGTTCCT„

4827,AI0855₅9„20, 160,AGGTCATAGTTCCTTATACA„

4828,AI085559„20, 154,TAGTTCCTTATACACAGACA„

4829,AI085559„20,148,CTTATACACAGACACCTGCA„ 4830,AI085559„20,142,CACAGACACCTGCATCATCG„

4831,AI085559„20,136,CACCTGCATCATCGAAGGTC„

4832,AI0855₅9„20,130,CATCATCGAAGGTCTTTTTT„

4833,AI08₅₅₅9„20,124,CGAAGGTCTTTTTTTCCTAA„

4834,AI08₅₅₅9„20, 118,TCTTTTTTTCCTAAAAAAAA„ 4835,AI085559„20,112,TTTCCTAAAAAAAAAAAATG„

4836,AI085559„20,106,AAAAAAAAAAAATGGGATTT„

4837,AI0855₅9„20,100,AAAAAATGGGATTTTAGTTC„

4S38,AI08₅559„20,94,TGGGATTTTAGTTCTTATTC„

4839,AI085559„20,88,TTTAGTTCTTATTCTGTGAT„ 4840,AI085559,,20,82,TCTTATTCTGTGATAACTAT„

4841,AI085559„20,76,TCTGTGATAACTATCCTCCT„

4842,AI085559„20,70,ATAACTATCCTCCTCATATA„

4843,AI085559„20,64,ATCCTCCTCATATAATACTA„

4844,AI085559„20,58,CTCATATAATACTATTCTTT„ 4845,AI085559„20,52,TAATACTATTCTTTTTGACA„

4846,AI085559„20,46,TATTCTTTTTGACACCATTT„

4847,AI085559„20,40,TTTTGACACCATTTGAAGGA„

4848,AI085559„20,34,CACCATTTGAAGGAACCAAT„

4849,AI085559„20,28,TTGAAGGAACCAATATTTGG„ 4850,AI085559„20,22,GAACCAATATTTGGACCTTA„

4851 ,AI085559„20, 16,ATATTTGGACCTTATTTTGA„

4852,AI085559„20, 10,GGACCTTATTTTGAGGTTGT„

4853,AI085559„20,4,TATTTTGAGGTTGTCTGTCT„

(GENBANK ACCESSION NO. AI654215) TTTTTTTTNTTTTTTTTTTTTTTTTTTGATGTTTCCCAGTACCACTTCAGCCTTGCCGGCTGCGTAAACTTTTGCTGTATCGAAAAGGTT

GATGCCATTATCATAGGCCAAGGTCATGAGCTGCTCTGCCATCTCATCGGTGATCTGGCCTCCGAAGGTCACCCATGTTCCAAGTCC

CAGGCAGGAAACCCGCAGGCCAAACTTGCCCAGGTTCCTGTAAATCATCCCGGGGGAGCCCGTCTGCCGCAGCGAGAGCCGAGCCG

GGGAGCCCGTCGTTGATTCTGGATACATGGAGCCAGCCTCACTTATCCAGACTTGCTCGGTTTTTTACAGGGGGAAAATTCTGCTCC

TGAACGGGAACGACCGGAGACAAGGCCATTTTCCGAGCACTCAGGGGAACGCCAGGTCAC (SEQ ID NO: 4854)

4855,AI654215„20,391,GTGACCTGGCGTTCCCCTGA„

4856.AI654215„20,385,TGGCGTTCCCCTGAGTGCTC„

4857.AI654215„20,379,TCCCCTGAGTGCTCGGAAAA„ 4858,AI654215„20,373,GAGTGCTCGGAAAATGGCCT„

4859.AI654215„20,367,TCGGAAAATGGCCTTGTCTC„

4860.AI654215„20,361.AATGGCCTTGTCTCCGGTCG,,

4861,AI654215„20,355,CTTGTCTCCGGTCGTTCCCG„

4862.AI654215,,20,349,TCCGGTCGTTCCCGTTCAGG„ 4863,AI654215„20,343,CGTTCCCGTTCAGGAGCAGA„

4864.AI654215„20,337,CGTTCAGGAGCAGAATTTTC„

4865,AI654215„20,331 ,GGAGCAGAATTTTCCCCCTG„

4866,AI654215„20,32₅,GAATTTTCCCCCTGTAAAAA„

4867,AI6₅4215„20,319,TCCCCCTGTAAAAAACCGAG„ 4868,AI654215„20,313,TGTAAAAAACCGAGCAAGTC„

4869.AI654215„20,307,AAACCGAGCAAGTCTGGATA„

4870,AI654215„20,301 ,AGCAAGTCTGGATAAGTGAG„

4871,AI654215„20,295,TCTGGATAAGTGAGGCTGGC„

4872,AI654215„20,289,TAAGTGAGGCTGGCTCCATG„ 4873,AI654215„20,283,AGGCTGGCTCCATGTATCCA„

4874.AI654215„20,277_SGCTCCATGTATCCAGAATCA„

4875,AI654215„20,271.TGTATCCAGAATCAACGACG,,

4876,AI654215„20,265,CAGAATCAACGACGGGCTCC„

4877.AI654215„20,259,CAACGACGGGCTCCCCGGCT„ 4878,AI654215„20,253,CGGGCTCCCCGGCTCGGCTC„

4879,AI654215„20,247,CCCCGGCTCGGCTCTCGCTG„

4880.AI654215„20,241 ,CTCGGCTCTCGCTGCGGCAG„

4881.AI654215„20,235,TCTCGCTGCGGCAGACGGGC„

4S82,AI654215„20,229,TGCGGCAGACGGGCTCCCCC„ 4883,AI654215„20,223,AGACGGGCTCCCCCGGGATG„

4884.AI654215„20,217,GCTCCCCCGGGATGATTTAC„

4885,AI654215„20,211,CCGGGATGATTTACAGGAAC„

4886,AI654215„20,205,TGATTTACAGGAACCTGGGC„

4887,AI654215„20, 199.ACAGGAACCTGGGCAAGTTT,, 4888.AI654215„20, 193.ACCTGGGCAAGTTTGGCCTG,,

4889.AI654215„20, 187,GCAAGTTTGGCCTGCGGGTT„

4890.AI654215„20, 181 ,TTGGCCTGCGGGTTTCCTGC„

4891.AI654215„20, 175,TGCGGGTTTCCTGCCTGGGA„

4892,AI654215„20,169,TTTCCTGCCTGGGACTTGGA„ 4893.AI654215„20, 163,GCCTGGGACTTGGAACATGG„ 4894.AI654215_: „20, 157,GACTTGGAACATGGGTGACC„

4895.AI654215 ,20, 151 ,GAACATGGGTGACCTTCGGA„

4896,AI654215_: ,20,145,GGGTGACCTTCGGAGGCCAG„

4897,AI654215„20, 139,CCTTCGGAGGCCAGATCACC„ 4898,AI654215„20,133,GAGGCCAGATCACCGATGAG„ 4899,AI654215„20,127,AGATCACCGATGAGATGGCA„ 4900,AI654215„20, 121 ,CCGATGAGATGGCAGAGCAG„ 4901 ,AI654215„20, 115,AGATGGCAGAGCAGCTCATG„ 4902.AI654215„20, 109,CAGAGCAGCTCATGACCTTG„ 4903,AI654215„20,103,AGCTCATGACCTTGGCCTAT„ 4904.AI654215„20,97,TGACCTTGGCCTATGATAAT„ 4905.AI654215„20,91.TGGCCTATGATAATGGCATC,, 4906.AI654215„20,85,ATGATAATGGCATCAACCTT„ 4907,AI654215„20,79,ATGGCATCAACCTTTTCGAT„ 4908.AI65421₅„20,73,TCAACCTTTTCGATACAGCA„ 4909.AI654215„20,67,TTTTCGATACAGCAAAAGTT„ 4910.AI654215„20,61 ,ATACAGCAAAAGTTTACGCA„ 4911 ,AI654215„20,55,CAAAAGTTTACGCAGCCGGC„ 4912,AI654215„20,49,TTTACGCAGCCGGCAAGGCT„ 4913,AI654215„20,43,CAGCCGGCAAGGCTGAAGTG„ 4914,AI654215„20,37,GCAAGGCTGAAGTGGTACTG„ 4915,AI654215„20,31 ,CTGAAGTGGTACTGGGAAAC„ 4916.AI654215„20,25,TGGTACTGGGAAACATCAAA„ 4917.AI654215„20, 19,TGGGAAACATCAAAAAAAAA„ 4918.AI654215„20, 13.ACATCAAAAAAAAAAAAAAA,, 4919.AI654215„20,7,AAAAAAAAAAAAAAAAANAA„ 4920,AI654215„20, 1 ,AAAAAAAAAAANAAAAAAAA„ (GENBANK ACCESSION NO. AA505075)

GAAATTGCTAACAACTCCAACCCTCTATATTGTGTTTCTTTTGCTCCTGGAGTCCTCTTGCAGCTTTAATTCTTGAAACTCAGGCGGC (SEQ ID NO: 4921)

4922,AA505075„20, 159,GCCGCCTGAGTTTCAAGAAT„

4923,AA505075„20,153,TGAGTTTCAAGAATTAAAGC„ 4924,AA505075„20,147,TCAAGAATTAAAGCTGCAAG„

4925,AA505075„20, 141 ,ATTAAAGCTGCAAGAGGACT„

4926,AA505075„20,135,GCTGCAAGAGGACTCCAGGA„

4927,AA505075„20, 129,AGAGGACTCCAGGAGCAAAA„

4928,AA50₅075„20,123,CTCCAGGAGCAAAAGAAACA„ 4929,AA505075„20,117,GAGCAAAAGAAACACAATAT„

4930,AA505075„20,111,AAGAAACACAATATAGAGGG„

4931,AA505075„20,105,CACAATATAGAGGGTTGGAG„

4932,AA505075„20,99,ATAGAGGGTTGGAGTTGTTA„

4933,AA505075„20,93,GGTTGGAGTTGTTAGCAATT„ 4934,AA505075„20,87,AGTTGTTAGCAATTTCATTC„

4935,AA505075„20,81,TAGCAATTTCATTCAAAATG„

4936,AA505075„20,75,TTTCATTCAAAATGCCAACT„

4937,AA505075„20,69,TCAAAATGCCAACTGGAGAA₎,

4938,AA505075„20,63,TGCCAACTGGAGAAGTCTGT„ 4939,AA505075„20,57,CTGGAGAAGTCTGTTTTTAA„

4940,AA505075„20,51,AAGTCTGTTTTTAAATACAT„

4941 ,AA505075„20,45,GTTTTTAAATACATTTTGTT„

4942,AA505075„20,39,AAATACATTTTGTTGTTATT„

4943,AA505075„20,33,ATTTTGTTGTTATTTTAAAA„ 4944,AA50507₅„20,27,TTGTTATTTTAAAAAAAAAA„

4945,AA505075„20,21.TTTTAAAAAAAAAAAAAAAA,,

4946,AA505075„20, 15,AAAAAAAAAAAAAAAAAAAA„

4947,AA505075„20,9,AAAAAAAAAAAAAAAAAAAA„

4948,AA505075„20,3,AAAAAAAAAAAAAAAAAAAA„ (GENBANK ACCESSION NO. AA906703)

TGAATTATGACAGAAATCTTTATTAAAATGTGTCTTTCAGTAATATGTTTAGCATTCAATATACACACATACATATGTACACTCTTTG

ACACGCCTCATGGATTGCTGCCATCAGTTTAACTAATAAATTAAAACTAAAAAGAGGGATGTGAGGGGAGGGGAACTAACGGCAAA

CTTTTCATGTTTTATCTGGTAAGAAATTGTGAATTTCTCAGAATTTCCCTGGGCAAAAACCTGTGACCAGAGAATCTGTGAAATAAA

ATACATAAATCTCTACCCCTTGGAAAAAAAAAAAAAAAAATTCCAAAAGATGCAGTTACAAGTGTGCTTCTCAGAACAGGAGCATT CATTCCACTTCATACTCTGGCT

(SEQ ID NO: 4949)

4950,AA906703„20,350_: AGCCAGAGTATGAAGTGGAA,, 4951,AA906703„20,344_: ΛGTATGAAGTGGAATGAATG,, 4952,AA906703„20,338_: ,AAGTGGAATGAATGCTCCTG„

49₅3,AA906703„20,332_: ,AATGAATGCTCCTGTTCTGA„ 49₅4,AA906703„20,326_; ,TGCTCCTGTTCTGAGAAGCA„ 49₅₅,AA906703„20,320, ,TGTTCTGAGAAGCACACTTG„ 4956,AA906703„20,314, ,GAGAAGCACACTTGTAACTG„ 4957,AA906703„20,308_; ,CACACTTGTAACTGCATCTT„ 4958,AA906703„20,302,TGTAACTGCATCTTTTGGAA„

4959,AA906703„20,296,TGCATCTTTTGGAATTTTTT„

4960,AA906703„20,290,TTTTGGAATTTTTTTTTTTT„

4961,AA906703„20,284,AATTTTTTTTTTTTTTTTTC„ 4962,AA906703„20,278,TTTTTTTTTTTTTCCAAGGG„

4963,AA906703„20,272,TTTTTTTCCAAGGGGTAGAG„

4964,AA906703„20,266,TCCAAGGGGTAGAGATTTAT„

4965,AA906703„20,260,GGGTAGAGATTTATGTATTT„

4966,AA906703„20,254,AGATTTATGTATTTTATTTC„ 4967,AA906703„20,248,ATGTATTTTATTTCACAGAT„

4968,AA906703„20,242,TTTATTTCACAGATTCTCTG„

4969,AA906703„20,236,TCACAGATTCTCTGGTCACA„

4970,AA906703„20,230,ATTCTCTGGTCACAGGTTTT„

4971,AA906703„20,224,TGGTCACAGGTTTTTGCCCA„ 4972,AA906703„20,218,CAGGTTTTTGCCCAGGGAAA„

4973,AA906703„20,212,TTTGCCCAGGGAAATTCTGA„

4974,AA906703„20,206,CAGGGAAATTCTGAGAAATT„

4975,AA906703„20,200,AATTCTGAGAAATTCACAAT„

4976,AA906703„20,194,GAGAAATTCACAATTTCTTA„ 4977,AA906703„20,188,TTCACAATTTCTTACCAGAT„

4978,AA906703„20, 182,ATTTCTTACCAGATAAAACA„

4979,AA906703„20,176,TACCAGATAAAACATGAAAA„

4980,AA906703„20,170,ATAAAACATGAAAAGTTTGC„

4981,AA906703„20,164,CATGAAAAGTTTGCCGTTAG„ 4982,AA906703„20,158,AAGTTTGCCGTTAGTTCCCC„

4983,AA906703„20,152,GCCGTTAGTTCCCCTCCCCT„

4984,AA906703„20,146,AGTTCCCCTCCCCTCACATC„

4985,AA906703„20,140,CCTCCCCTCACATCCCTCTT„

4986,AA906703„20,134,CTCACATCCCTCTTTTTAGT„ 4987,AA906703„20,128,TCCCTCTTTTTAGTTTTAAT„

4988,AA906703„20,122,TTTTTAGTTTTAATTTATTA„

4989,AA906703„20, 116,GTTTTAATTTATTAGTTAAA„

4990,AA906703„20,110,ATTTATTAGTTAAACTGATG„

4991 ,AA906703„20, 104,TAGTTAAACTGATGGCAGCA„ 4992,AA906703„20,98,AACTGATGGCAGCAATCCAT„

4993,AA906703„20,92,TGGCAGCAATCCATGAGGCG„

4994,AA906703„20,86,CAATCCATGAGGCGTGTCAA„

4995,AA906703„20,S0,ATGAGGCGTGTCAAAGAGTG„

4996,AA906703₎,20,74,CGTGTCAAAGAGTGTACATA„ 4997,AA906703„20,68,AAAGAGTGTACATATGTATG„

4998,AA906703„20,62,TGTACATATGTATGTGTGTA„

4999,AA906703„20,56,TATGTATGTGTGTATATTGA„

5000,AA906703„20,50,TGTGTGTATATTGAATGCTA„

5001,AA906703„20,44,TATATTGAATGCTAAACATA„ 5002,AA906703„20,38,GAATGCTAAACATATTACTG„

5003,AA906703„20,32,TAAACATATTACTGAAAGAC„

5004,AA906703„20,26,TATTACTGAAAGACACATTT„

5005,AA906703„20,20,TGAAAGACACATTTTAATAA„

5006,AA906703„20,14,ACACATTTTAATAAAGATTT„ 5007,AA906703„20,8,TTTAATAAAGATTTCTGTCA„

5008,AA906703„20,2,AAAGATTTCTGTCATAATTC„

(GENBANK ACCESSION NO. AI369870)

GGCCCGCGGGGAGCGCGGCGCAATTCGTCGGCCCGCGGGGGGGCGGCCTCCCGGCATCTTCGCGGCGACCAAGGACTACCAGGAA

GGGGAGCGGCTGGGATGGCGCGTCCGCGGCCCCGCGAGTACAAAGCGGGCGACCTGGTCTTCGCCAAGATGAAGGGCTACCCGCA CTGGCCGGCCCGGATTGATGAACTCCCAGAGGGCGCTGTGAAGCCTCCAGCAAACAAGTATCCTATCTTCTTTTTTGGCACCCATGA

AACTGCATTTCTAGGTCCCAAAGACCTTTTTCCATATAAGGAGTACAAAGACAAGTTTGGAAAGTCAAACAAACGGAAAGGATTTA

ACGAAGGATTGTGGGAAATAGAAAATAACCCAGGAGTAAAGTTTACTGGCTACCAGGCAATTCAGCAACAGAGCTCTTCAGAAACT

GAGGGAGAAGGTGGAAATACTGCAGATGCAAGCAGTGA

(SEQ ID NO: 5009)

5010,AI369870„20,44S,TCACTGCTTGCATCTGCAGT„

5011,AI369870„20,442,CTTGCATCTGCAGTATTTCC„

5012,AI369870„20,436,TCTGCAGTATTTCCACCTTC„

5013,AI369870„20,430,GTATTTCCACCTTCTCCCTC„ 5014,AI369870„20,424,CCACCTTCTCCCTCAGTTTC„

₅015,AI369870„20,418,TCTCCCTCAGTTTCTGAAGA„

5016,AI369870„20,412,TCAGTTTCTGAAGAGCTCTG„

₅017,AI369870„20,406,TCTGAAGAGCTCTGTTGCTG„

5018,AI369870„20,400,GAGCTCTGTTGCTGAATTGC„ 5019,AI369870„20,394,TGTTGCTGAATTGCCTGGTA„

5020,AI369870„20,388,TGAATTGCCTGGTAGCCAGT„

5021,AI369870„20,382,GCCTGGTAGCCAGTAAACTT„

5022,AI369870„20,376,TAGCCAGTAAACTTTACTCC„

5023,AI369870„20,370,GTAAACTTTACTCCTGGGTT„ 5024,AI369870„20,364 TTACTCCTGGGTTATTTTC„ 5025,AI369870„20,358,CCTGGGTTATTTTCTATTTC„

5026,AI369870„20,352,TTATTTTCTATTTCCCACAA„

5027,AI369870„20,346,TCTATTTCCCACAATCCTTC„

5028,AI369870„20,340,TCCCACAATCCTTCGTTAAA„ 5029,AI369870„20,334,AATCCTTCGTTAAATCCTTT„

5030,AI369870„20,328,TCGTTAAATCCTTTCCGTTT„

5031 ,AI369870„20,322,AATCCTTTCCGTTTGTTTGA„

5032,AI369870„20,316,TTCCGTTTGTTTGACTTTCC„

₅033,AI369870„20,310,TTGTTTGACTTTCCAAACTT„ ₅034,AI369870„20,304,GACTTTCCAAACTTGTCTTT„

5035,AI369870„20,298,CCAAACTTGTCTTTGTACTC„

5036,AI369870„20,292,TTGTCTTTGTACTCCTTATA,,

5037,AI369870„20,286,TTGTACTCCTTATATGGAAA„

5038,AI369870„20,280,TCCTTATATGGAAAAAGGTC„ 5039,AI369870„20,274,TATGGAAAAAGGTCTTTGGG„

5040,AI369870„20,268,AAAAGGTCTTTGGGACCTAG„

5041,AI369870„20,262,TCTTTGGGACCTAGAAATGC„

₅042,AI369870„20,256,GGACCTAGAAATGCAGTTTC„

5043,AI369870„20,250,AGAAATGCAGTTTCATGGGT„ 5044,AI369870„20,244,GCAGTTTCATGGGTGCCAAA„

5045,AI369870„20,238,TCATGGGTGCCAAAAAAGAA„

₅046,AI369870„20,232,GTGCCAAAAAAGAAGATAGG„

₅047,AI369870„20,226,AAAAAGAAGATAGGATACTT„

₅048,AI369870„20,220,AAGATAGGATACTTGTTTGC„ 5049,AI369870„20,214,GGATACTTGTTTGCTGGAGG„

5050,AI369870„20,208,TTGTTTGCTGGAGGCTTCAC„

5051,AI369870„20,202,GCTGGAGGCTTCACAGCGCC„

5052,AI369870„20,196,GGCTTCACAGCGCCCTCTGG„

5053,AI369870„20,190,ACAGCGCCCTCTGGGAGTTC„ 5054,AI369870„20,184,CCCTCTGGGAGTTCATCAAT„

5055,AI369870„20,178,GGGAGTTCATCAATCCGGGC„

5056,AI369870„20,172,TCATCAATCCGGGCCGGCCA„

5057,AI369870„20, 166,ATCCGGGCCGGCCAGTGCGG„

5058,AI369870„20,160,GCCGGCCAGTGCGGGTAGCC„ 5059,AI369870„20, 154,CAGTGCGGGTAGCCCTTCAT„

5060,AI369870„20,148,GGGTAGCCCTTCATCTTGGC„

5061,AI369870„20,142,CCCTTCATCTTGGCGAAGAC„

5062,AI369870„20,136,ATCTTGGCGAAGACCAGGTC„

5063,AI369870„20,130,GCGAAGACCAGGTCGCCCGC„ 5064,AI369870„20,124,ACCAGGTCGCCCGCTTTGTA„

5065,AI369870„20, 118,TCGCCCGCTTTGTACTCGCG„

5066,AI369870„20,112,GCTTTGTACTCGCGGGGCCG„

5067,AI369870„20,106,TACTCGCGGGGCCGCGGACG„

5068,AI369870„20,100,CGGGGCCGCGGACGCGCCAT„ 5069,AI369870„20,94,CGCGGACGCGCCATCCCAGC„

5070,AI369870„20,88,CGCGCCATCCCAGCCGCTCC„

5071,AI369870„20,82,ATCCCAGCCGCTCCCCTTCC„

5072,AI369870„20,76,GCCGCTCCCCTTCCTGGTAG„

5073,AI3^'69870„20,70,CCCCTTCCTGGTAGTCCTTG„ 5074,AI369870„20,64,CCTGGTAGTCCTTGGTCGCC„

5075,AI369870„20,58,AGTCCTTGGTCGCCGCGAAG„

5076,AI369870„20,₅2,TGGTCGCCGCGAAGATGCCG„

5077,AI369870„20,46,CCGCGAAGATGCCGGGAGGC„

5078,AI369870„20,40,AGATGCCGGGAGGCCGCCCC„ 5079,AI369870„20,34,CGGGAGGCCGCCCCCCCGCG„

5080,AI369870„20,28,GCCGCCCCCCCGCGGGCCGA„

5081,AI369870„20,22,CCCCCGCGGGCCGACGAATT„

5082,AI369870„20,16,CGGGCCGACGAATTGCGCCG„

5083,AI369870„20,10,GACGAATTGCGCCGCGCTCC„ 5084,AI369870„20,4,TTGCGCCGCGCTCCCCGCGG„ _τ (G_τE_τN_τB_τA_ττN_τK_τ A_ττC_τC_τE_τS_τS_τIO_τN_ττ N_cO_c._χ A_cA_A4_A6_G32_A4_A9)_{AAAAAGTTTAATAGCAAG}

AACACTTAAAAGGATACAACAGGTACTTATTAAATGCTGCCTTGCCTTTTACCTCTTCCTTTTTTTTTTTTTTTTGAGATGGAGTCTCG CTCTGCTGCCCAGCCTGAAGTGCAGTGGTGTGATCTCGGCTCACTGCAACCTCCGCCTTCCAGGTTTAGGTGATTCTCTTGCCTCGGC CTCCCGAGTAGCTGGGATGGACTACAGGCACATGTCACCATGCCCAGCTAATTTTTTGTATTTTTAGTA

(SEQ ID NO: 5085)

5086,AA463249„20,315,TACTAAAAATACAAAAAATT„ 5087,AA463249„20,309,AAATACAAAAAATTAGCTGG„ 5088,AA463249„20,303,AAAAAATTAGCTGGGCATGG„

5089,AA463249„20,297,TTAGCTGGGCATGGTGACAT„ 5090,AA463249„20,291 ,GGGCATGGTGACATGTGCCT„ 5091 ,AA463249„20,28₅,GGTGACATGTGCCTGTAGTC„ 5092,AA463249„20,279,ATGTGCCTGTAGTCCATCCC„ 5093,AA463249„20,273,CTGTAGTCCATCCCAGCTAC„ 5094,AA463249„20,267,TCCATCCCAGCTACTCGGGA„

5095,AA463249„20,261 ,CCAGCTACTCGGGAGGCCGA„

5096,AA463249„20,255,ACTCGGGAGGCCGAGGCAAG„

5097,AA463249„20,249,GAGGCCGAGGCAAGAGAATC„ 5098,AA463249„20,243,GAGGCAAGAGAATCACCTAA„

5099,AA463249„20,237,AGAGAATCACCTAAACCTGG„

5100,AA463249„20,231,TCACCTAAACCTGGAAGGCG„

5101 ,AA463249„20,225,AAACCTGGAAGGCGGAGGTT„

5102,AA463249„20,219,GGAAGGCGGAGGTTGCAGTG„ 5103,AA463249„20,213,CGGAGGTTGCAGTGAGCCGA„

5104,AA463249„20,207,TTGCAGTGAGCCGAGATCAC„

5105,AA463249„20,201 ,TGAGCCGAGATCACACCACT„

5106, AA463249„20, 195,GAGATCACACCACTGCACTT„

5107,AA463249„20,189,ACACCACTGCACTTCAGGCT„ 5108,AA463249„20,183,CTGCACTTCAGGCTGGGCAG„

5109,AA463249„20,177,TTCAGGCTGGGCAGCAGAGC„

5110,AA463249„20,171,CTGGGCAGCAGAGCGAGACT„

5111 ,AA463249„20, 165,AGCAGAGCGAGACTCCATCT„

5112,AA463249„20, 159,GCGAGACTCCATCTCAAAAA„ 5113,AA463249„20, 153,CTCCATCTCAAAAAAAAAAA„

5114,AA463249„20,147,CTCAAAAAAAAAAAAAAAAG„

5115,AA463249„20,141,AAAAAAAAAAAAAGGAAGAG„

5116,AA463249„20, 135,AAAAAAAGGAAGAGGTAAAA„

5117,AA463249„20, 129,AGGAAGAGGTAAAAGGCAAG„ 5118,AA463249„20, 123,AGGTAAAAGGCAAGGCAGCA„

5119,AA463249„20,117,AAGGCAAGGCAGCATTTAAT„

5120,AA463249„20,111,AGGCAGCATTTAATAAGTAC„

5121 ,AA463249„20, 105,CATTTAATAAGTACCTGTTG„

5122,AA463249„20,99,ATAAGTACCTGTTGTATCCT„ 5123,AA463249„20,93,ACCTGTTGTATCCTTTTAAG„

5124,AA463249„20,87,TGTATCCTTTTAAGTGTTTG„

5125,AA463249„20,81 ,CTTTTAAGTGTTTGTTGTGG„

5126,AA463249„20,75,AGTGTTTGTTGTGGTAATCC„

5127,AA463249„20,69,TGTTGTGGTAATCCTCACAA„ 5128,AA463249„20,63,GGTAATCCTCACAAAGACCG„

5129,AA463249„20,57,CCTCACAAAGACCGGGACTG„

5130,AA463249„20,51 ,AAAGACCGGGACTGATGGAA„

5131 ,AA463249„20,45,CGGGACTGATGGAAACTCCT„

5132,AA463249„20,39,TGATGGAAACTCCTTGCTAT„ 5133,AA463249„20,33,AAACTCCTTGCTATTAAACT„

5134,AA463249„20,27_SCTTGCTATTAAACTTTTTTT„

5135,AA463249„20,21 ,ATTAAACTTTTTTTCTTGAG„

5136,AA463249„20, 15,CTTTTTTTCTTGAGGAAAAA„

5137,AA463249„20,9,TTCTTGAGGAAAAAAAAAAA„ ₅138,AA463249„20,3,AGGAAAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. R38894)

TTTTTTACAGCATAGCGGTTTATTCATGCCATCATACAGTCGATCTGTATTCTTCAAGTACATTTTGAATTTATAATGAAGACAGTTT

AAGGCATAACTCTTCCCACTCAAATCTATGGTCTTTCTCAAGTGAGACACTAGAGAGAGTAGAANGGGAGGNTGAGATAGGGC

(SEQ ID NO: 5139)

5140,R38894„20,152,GCCCTATCTCANCCTCCCNT„

5141,R38894„20,146,TCTCANCCTCCCNTTCTACT„

5142,R38894„20,140,CCTCCCNTTCTACTCTCTCT„

5143,R38894„20,134,NTTCTACTCTCTCTAGTGTC„ 5144,R38894„20,128,CTCTCTCTAGTGTCTCACTT„

₅145,R38894„20,122,CTAGTGTCTCACTTGAGAAA„

5146,R38894„20,116,TCTCACTTGAGAAAGACCAT„

5147,R38894„20,110,TTGAGAAAGACCATAGATTT„

5148,R38894„20,104,AAGACCATAGATTTGAGTGG„ 5149,R38894„20,98,ATAGATTTGAGTGGGAAGAG„

5150,R38894„20,92,TTGAGTGGGAAGAGTTATGC„

5151,R38894„20,86,GGGAAGAGTTATGCCTTAAA„

5152,R38894„20,80,AGTTATGCCTTAAACTGTCT„

5153,R38894„20,74,GCCTTAAACTGTCTTCATTA„ 5154,R38894„20,68,AACTGTCTTCATTATAAATT„

₅155,R38894„20,62,CTTCATTATAAATTCAAAAT„

5156,R38894„20,56,TATAAATTCAAAATGTACTT„

5157,R38894„20,50,TTCAAAATGTACTTGAAGAA„

5158,R38894„20,44,ATGTACTTGAAGAATACAGA„ 5159,R38894„20,38,TTGAAGAATACAGATCGACT„

₅160₎R38894„20,32,AATACAGATCGACTGTATGA„

5161,R38894„20,26,GATCGACTGTATGATGGCAT„

5162,R38894„20,20,CTGTATGATGGCATGAATAA„

5163,R38894„20,14,GATGGCATGAATAAACCGCT„ 5164,R38894„20,8,ATGAATAAACCGCTATGCTG„ ₅165,R38894„20,2,AAACCGCTATGCTGTAAAAA„

( _τG_πEN_τB_τA_ττN_τK_τ A_ττC_τC_τE_τS_TS_GIO_GN_A N_GAO_T. R_G4_A9_C14_C4_T)_GN^^

TGCTCAGAGGTGCAGTGGCCAAACAACTCTAGGAGATCGCCTGTNTTCCCTCCCATCCCCCAAGCTTATGACGTGGCTCCATGCCCA GGGAACTTTGGGCCANCCCANCCCCANTCCCAAACCCTCATAATNCACAGAGGGAGCCTGGGCCAAG

(SEQ ID NO: 5166)

5167,R49144„20,222,CTTGGCCCAGGCTCCCTCTG„

5168,R49144„20,216,CCAGGCTCCCTCTGTGNATT„ 5169,R49144„20,210,TCCCTCTGTGNATTATGAGG„

5170,R49144„20,204,TGTGNATTATGAGGGTTTGG„

5171,R49144„20,198,TTATGAGGGTTTGGGANTGG„

5172,R49144„20, 192,GGGTTTGGGANTGGGGNTGG„

5173.R49144„20, 186,GGGANTGGGGNTGGGNTGGC„ 5174,R49144„20,180,GGGGNTGGGNTGGCCCAAAG„

5175,R49144„20,174,GGGNTGGCCCAAAGTTCCCT„

5176.R49144„20, 168,GCCCAAAGTTCCCTGGGCAT„

5177.R49144„20, 162,AGTTCCCTGGGCATGGAGCC„

5178,R49144„20,156,CTGGGCATGGAGCCACGTCA„ 5179,R49144„20,150,ATGGAGCCACGTCATAAGCT„

5180.R49144„20, 144.CCACGTCATAAGCTTGGGGG,,

5181 ,R49144„20, 138,CATAAGCTTGGGGGATGGGA„

5182,R49144„20,132,CTTGGGGGATGGGAGGGAAN„

5183,R49144„20,126,GGATGGGAGGGAANACAGGC„ 5184,R49144„20,120,GAGGGAANACAGGCGATCTC„

5185,R49144„20,114,ANACAGGCGATCTCCTAGAG„

5186,R49144„20,108,GCGATCTCCTAGAGTTGTTT„

5187,R49144„20,102,TCCTAGAGTTGTTTGGCCAC„

5188,R49144„20,96,AGTTGTTTGGCCACTGCACC„ 5189,R49144„20,90,TTGGCCACTGCACCTCTGAG„

5190.R49144„20,84,ACTGCACCTCTGAGCAGCTT„

5191,R49144„20,78,CCTCTGAGCAGCTTTGCATA„

5192,R49144„20,72,AGCAGCTTTGCATAGCTTCC„

5193,R49144„20,66,TTTGCATAGCTTCCTGTCTT„ 5194,R49144„20,60,TAGCTTCCTGTCTTGCTGCT„

5195,R49144„20,₅4,CCTGTCTTGCTGCTTTGCTG„

5196,R49144„20,48,TTGCTGCTTTGCTGGAGCTG„

5197,R49144„20,42,CTTTGCTGGAGCTGGGGCTG„

5198,R49144„20,36,TGGAGCTGGGGCTGTGCCAT„ 5199,R49144„20,30₎TGGGGCTGTGCCATTAAAAG„

5200,R49144„20,24,TGTGCCATTAAAAGTNCAGG„

5201 ,R49144„20, 18,ATTAAAAGTNCAGGTCATCT„

5202,R49144„20,12,AGTNCAGGTCATCTCCAAAA„

5203,R49144„20,6₎GGTCATCTCCAAAAAAAAAA„ (GENBANK ACCESSION NO. AA398883)

TATGTCACTATTTTATTGATGATGTGTTTTATAGAATCACAAAATTTAGAAACATAAGAAGGATTTAGGTATCACCTAAATTCAAAG

AAATGTGTGTTTCTAGGTTGCTAAATTCAAAGAAAAAGTATGATTTGGTTTGGTTCATTTAAAACAGGTCACAAACAGAATTATATT

TCAAATTTAGAAGATACGGTATTAAGTGATTCATCTTATTTTGGACATTTTTCCTCAAGGAGAATTTTTCTGGAAGAAAAAGTACATT

TATATGTGGGCTTATTAAGAGAAAGAGAGAAAGGCATGCTATTTTAATCATTAAATTCTTGATGATGACGATCATCATCAAGATGAG AAAGAAAAGAAATATGAGCCAAGAGAATCTGTTGTTGCCAGCAATCAGTTTACCAGAACATCTGCAGGTGAACATTTTCCAAATGG

AGTGACAGACTAATTGCATCTACGGGGATGAGAATCTGCCATAGAGAGGATGCTGTGGGCTTATTTTGCTTATGTAGATAGGAAGG

GTGATACATGGA

(SEQ ID NO: 5204) 5205,AA398883„20,514,TCCATGTATCACCCTTCCTA„

5206,AA398883„20,₅08,TATCACCCTTCCTATCTACA„

5207,AA398883„20,502,CCTTCCTATCTACATAAGCA„

5208,AA398883„20,496,TATCTACATAAGCAAAATAA„

5209,AA39S883„20,490,CATAAGCAAAATAAGCCCAC„ 5210,AA398883„20,484,CAAAATAAGCCCACAGCATC„

5211,AA398883„20,478,AAGCCCACAGCATCCTCTCT„

5212,AA398883„20,472,ACAGCATCCTCTCTATGGCA„

5213,AA398883„20,466,TCCTCTCTATGGCAGATTCT„

5214,AA398883„20,460,CTATGGCAGATTCTCATCCC„ 5215,AA398883„20,454,CAGATTCTCATCCCCGTAGA„

52i6,AA398883„20,448,CTCATCCCCGTAGATGCAAT„

5217,AA398883„20,442,CCCGTAGATGCAATTAGTCT„

5218,AA398883„20,436,GATGCAATTAGTCTGTCACT„

5219,AA398883„20,430,ATTAGTCTGTCACTCCATTT„ 5220,AA398883„20,424,CTGTCACTCCATTTGGAAAA„

5221,AA398883„20,418,CTCCATTTGGAAAATGTTCA„

5222,AA398883„20,412,TTGGAAAATGTTCACCTGCA„

5223,AA398883„20,406,AATGTTCACCTGCAGATGTT„

5224,AA398883„20,400,CACCTGCAGATGTTCTGGTA„ 5225,AA398883„20,394,CAGATGTTCTGGTAAACTGA„ 5226,AA398883„20,388,TTCTGGTAAACTGATTGCTG„

5227,AA3988S3„20,382,TAAACTGATTGCTGGCAACA„

5228,AA398883„20,376,GATTGCTGGCAACAACAGAT„

5229,AA398883„20,370,TGGCAACAACAGATTCTCTT„ ₅230,AA398883„20,364,CAACAGATTCTCTTGGCTCA„

5231,AA398883„20,358,ATTCTCTTGGCTCATATTTC„

5232,AA398883„20,352,TTGGCTCATATTTCTTTTCT„

5233,AA398883„20,346,CATATTTCTTTTCTTTCTCA„

5234,AA398883„20,340,TCTTTTCTTTCTCATCTTGA„ 523₅,AA398883„20,334,CTTTCTCATCTTGATGATGA„

5236,AA398883„20,328,CATCTTGATGATGATCGTCA„

5237,AA398883„20,322,GATGATGATCGTCATCATCA„

5238,AA398883„20,316,GATCGTCATCATCAAGAATT„

5239,AA398883„20,310,CATCATCAAGAATTTAATGA„ 5240,AA398883„20,304,CAAGAATTTAATGATTAAAA„

5241,AA398883„20,298,TTTAATGATTAAAATAGCAT„

5242,AA398883„20,292,GATTAAAATAGCATGCCTTT„

5243,AA398883„20,286,AATAGCATGCCTTTCTCTCT„

5244,AA398883„20,280,ATGCCTTTCTCTCTTTCTCT„ 5245,AA398883„20,274,TTCTCTCTTTCTCTTAATAA„

5246,AA398883„20,268,CTTTCTCTTAATAAGCCCAC„

5247,AA398883„20,262,CTTAATAAGCCCACATATAA„

5248,AA398883„20,256,AAGCCCACATATAAATGTAC„

5249,AA398883„20,2₅0,ACATATAAATGTACTTTTTC„ ₅250,AA398883„20,244,AAATGTACTTTTTCTTCCAG„

5251,AA398883„20,238,ACTTTTTCTTCCAGAAAAAT„

5252,AA398883„20,232,TCTTCCAGAAAAATTCTCCT„

5253,AA398883„20,226,AGAAAAATTCTCCTTGAGGA„

5254,AA398883„20,220,ATTCTCCTTGAGGAAAAATG„ 5255,AA398883„20,214,CTTGAGGAAAAATGTCCAAA„

5256,AA398883„20,208,GAAAAATGTCCAAAATAAGA„

5257,AA398883„20,202,TGTCCAAAATAAGATGAATC„

₅258,AA398883„20,196,AAATAAGATGAATCACTTAA„

5259,AA398883„20_S190,GATGAATCACTTAATACCGT„ 5260,AA398883„20,184,TCACTTAATACCGTATCTTC„

5261,AA398883„20,178,AATACCGTATCTTCTAAATT„

₅262,AA398883„20,172,GTATCTTCTAAATTTGAAAT„

5263,AA398883„20,166,TCTAAATTTGAAATATAATT„

5264,AA398883„20,160,TTTGAAATATAATTCTGTTT„ 5265,AA398883„20,154,ATATAATTCTGTTTGTGACC„

5266,AA398883„20,148,TTCTGTTTGTGACCTGTTTT„

5267,AA3988S3„20,142,TTGTGACCTGTTTTAAATGA„

5268,AA3988S3„20,136,CCTGTTTTAAATGAACCAAA„

5269,AA398883„20,130,TTAAATGAACCAAACCAAAT„ 5270,AA398883„20,124,GAACCAAACCAAATCATACT„

5271 ,AA398883„20, 118,AACCAAATCATACTTTTTCT„

5272,AA398883„20,112,ATCATACTTTTTCTTTGAAT„

5273,AA398883„20,106,CTTTTTCTTTGAATTTAGCA„

5274,AA398883„20,100,CTTTGAATTTAGCAACCTAG„ 5275,AA398883„20,94,ATTTAGCAACCTAGAAACAC„

5276,AA398883„20,88,CAACCTAGAAACACACATTT„

5277,AA398883„20,82₎AGAAACACACATTTCTTTGA„

5278,AA398883„20,76,ACACATTTCTTTGAATTTAG„

5279,AA398883„20,70,TTCTTTGAATTTAGGTGATA„ 5280,AA398883„20,64,GAATTTAGGTGATACCTAAA„

5281,AA398883„20,58,AGGTGATACCTAAATCCTTC„

5282,AA398883„20,52,TACCTAAATCCTTCTTATGT„

5283,AA398883„20,46_JAATCCTTCTTATGTTTCTAA„

5284,AA398883„20,40,TCTTATGTTTCTAAATTTTG„ 528₅,AA398883„20,34,GTTTCTAAATTTTGTGATTC„

5286,AA398883„20,28,AAATTTTGTGATTCTATAAA„

5287,AA398883„20,22,TGTGATTCTATAAAACACAT„

5288,AA398883„20,16,TCTATAAAACACATCATCAA„

5289,AA398883„20,10,AAACACATCATCAATAAAAT„ 5290,AA398883„20,4,ATCATCAATAAAATAGTGAC„

(GENBANK ACCESSION NO. AA425700)

CACATTTTATTTAATCTTTTATTTGAATCAAGGGAACCCTCATATGGAGAATAGAGACCCAAAGAACAGTTGGGATCAAGAGCTTAT

TTACTTTTTAAAGAAATGATACATTTGTGGAAAATTGATCAAATAAAGAGCTTTAGGCTAAGGGCAGTAAATTGTGGCATGACTAAG

AAATAGATGGTGGATATGAGTGGAAGATAAGGAGTATTTCAGTAGATTTGTTTGTACAGATCCATTTCGTCATCTACTCCCAGTCTC CAGTAAGGATGTTCTTCTCTTCTGGAACAGAAGGGGCACTTTCTCATGGGAAATTGTATTACCTGCTTTTAGGGAGACAGCAGGTCA

GGGAACCCTTCCTG

(SEQ ID NO: 5291)

5292,AA425700„20,343,CAGGAAGGGTTCCCTGACCT„ 5293,AA425700„20,337,GGGTTCCCTGACCTGCTGTC„ 5294,AA425700„20,331 ,CCTGACCTGCTGTCTCCCTA„

5295,AA425700„20,325,CTGCTGTCTCCCTAAAAGCA„

5296,AA425700„20,319,TCTCCCTAAAAGCAGGTAAT„

5297,AA425700„20,313,TAAAAGCAGGTAATACAATT„ 5298,AA425700„20,307,CAGGTAATACAATTTCCCAT„

₅299,AA425700„20,301 ,ATACAATTTCCCATGAGAAA„

₅300,AA425700„20,295,TTTCCCATGAGAAAGTGCCC„

5301 , AA425700„20,289,ATGAGAAAGTGCCCCTTCTG„

5302,AA42₅700„20,283,AAGTGCCCCTTCTGTTCCAG„ 5303,AA425700„20,277,CCCTTCTGTTCCAGAAGAGA„

5304,AA425700„20,271 ,TGTTCCAGAAGAGAAGAACA„

5305,AA42₅700„20,265,AGAAGAGAAGAACATCCTTA„

5306,AA425700„20,259,GAAGAACATCCTTACTGGAG„

5307,AA425700„20,253,CATCCTTACTGGAGACTGGG„ ι 5308,AA425700„20,247,TACTGGAGACTGGGAGTAGA„

5309,AA425700„20,241 ,AGACTGGGAGTAGATGACGA„

5310,AA425700„20,235,GGAGTAGATGACGAAATGGA„

5311 ,AA425700„20,229,GATGACGAAATGGATCTGTA„

5312,AA425700„20,223,GAAATGGATCTGTACAAACA„ 5313,AA425700„20,217,GATCTGTACAAACAAATCTA„

5314,AA425700„20,211 ,TACAAACAAATCTACTGAAA„

5315,AA425700„20,205,CAAATCTACTGAAATACTCC„

₅316,AA425700„20, 199,TACTGAAATACTCCTTATCT„

5317,AA425700„20,193,AATACTCCTTATCTTCCACT„ 5318,AA425700„20, 187,CCTTATCTTCCACTCATATC„

5319,AA425700„20, 181 ,CTTCCACTCATATCCACCAT„

5320,AA425700„20,175,CTCATATCCACCATCTATTT„

5321 ,AA425700„20, 169.TCCACCATCTATTTCTTAGT,,

5322,AA425700„20,163,ATCTATTTCTTAGTCATGCC„ 5323,AA425700„20,157,TTCTTAGTCATGCCACAATT„

5324,AA425700„20, 151 ,GTCATGCCACAATTTACTGC„

5325,AA425700„20,145,CCACAATTTACTGCCCTTAG„

5326,AA425700„20, 139,TTTACTGCCCTTAGCCTAAA„

5327,AA425700„20, 133,GCCCTTAGCCTAAAGCTCTT„ 5328,AA425700„20,127,AGCCTAAAGCTCTTTATTTG„

5329,AA425700„20,121,AAGCTCTTTATTTGATCAAT„

5330,AA425700„20, 115,TTTATTTGATCAATTTTCCA„

5331 ,AA425700„20, 109.TGATCAATT TTCCACAAATG,,

5332,AA425700„20,103,ATTTTCCACAAATGTATCAT„ 5333,AA425700„20,97,CACAAATGTATCATTTCTTT„

5334,AA425700„20,91,TGTATCATTTCTTTAAAAAG„

5335,AA425700„20,85,ATTTCTTTAAAAAGTAAATA„

5336,AA425700„20,79,TTAAAAAGTAAATAAGCTCT„

5337,AA425700„20,73,AGTAAATAAGCTCTTGATCC„ 5338,AA425700„20,67,TAAGCTCTTGATCCCAACTG„

5339,AA425700„20,61,CTTGATCCCAACTGTTCTTT„

5340,AA425700„20,55,CCCAACTGTTCTTTGGGTCT„

5341 ,AA425700„20,49,TGTTCTTTGGGTCTCTATTC„

5342,AA425700„20,43,TTGGGTCTCTATTCTCCATA„ 5343,AA425700„20,37,CTCTATTCTCCATATGAGGG„

5344,AA425700„20,31 ,TCTCCATATGAGGGTTCCCT„

5345,AA425700„20,2₅,TATGAGGGTTCCCTTGATTC„

₅346,AA425700„20, 19.GGTTCCCTTGATTCAAATAA,,

5347,AA42₅700„20,13,CTTGATTCAAATAAAAGATT„ ₅348,AA425700„20,7,TCAAATAAAAGATTAAATAA„

5349,AA425700„20, 1 ,AAAAGATTAAATAAAATGTG„

(GENBANK ACCESSION NO. AA459692)

GCCTGTTAATACAGTAGTTGTAAAATTGTACGTGTATTAGCAAGGAAACATAAACCTGCCTGGAATAAACTGTAAACCATGGAATAT

CAGACACCTGCCTGATATTCTCACTACAAACATTTCGTGGTCAAAATTGTCTTCTGACGATGATGGTCATTTGGAGAACAAAAACAG CAAAGCAAGAGGAGAGAACAAGAGTATCCTGAGGCGGTCTCCTGCAGTGCTCATAGCTGTTCCTCCTTAGCCTTCCACCTGGTGGCC

CTGGACTAGACCTCCAGAGAATTCC

(SEQ LD NO: 5350)

5351,AA459692„20,267,GGAATTCTCTGGAGGTCTAG„ 5352,AA459692„20,261 ,CTCTGGAGGTCTAGTCCAGG„

5353,AA459692„20,2₅₅,AGGTCTAGTCCAGGGCCACC„

5354,AA459692„20,249,AGTCCAGGGCCACCAGGTGG„

₅355,AA459692„20,243,GGGCCACCAGGTGGAAGGCT„

5356,AA459692„20,237,CCAGGTGGAAGGCTAAGGAG„ 5357,AA459692„20,231 ,GGAAGGCTAAGGAGGAACAG„

5358,AA459692„20,225,CTAAGGAGGAACAGCTATGA„

5359,AA459692„20,219,AGGAACAGCTATGAGCACTG„

5360,AA459692„20,213,AGCTATGAGCACTGCAGGAG„

5361 ,AA459692„20,207,GAGCACTGCAGGAGACCGCC„ 5362,AA459692„20,201,TGCAGGAGACCGCCTCAGGA„ 5363,AA459692„20,195,AGACCGCCTCAGGATACTCT„

5364,AA459692„20,189,CCTCAGGATACTCTTGTTCT„

5365,AA459692„20,183,GATACTCTTGTTCTCTCCTC„

5366,AA459692„20,177,CTTGTTCTCTCCTCTTGCTT„ 5367,AA459692„20,171,CTCTCCTCTTGCTTTGCTGT„

₅368,AA4₅9692„20,165,TCTTGCTTTGCTGTTTTTGT„

₅369,AA4₅9692„20,159,TTTGCTGTTTTTGTTCTCCA„

₅370,AA459692„20,153,GTTTTTGTTCTCCAAATGAC„

5371 ,AA459692„20, 147,GTTCTCCAAATGACCATCAT„ 5372,AA459692„20, 141 ,CAAATGACCATCATCGTCAG„

5373,AA459692„20,135,ACCATCATCGTCAGAAGACA„

5374,AA459692„20,129,ATCGTCAGAAGACAATTTTG„

537₅,AA459692„20,123,AGAAGACAATTTTGACCACG„

5376,AA459692„20,117,CAATTTTGACCACGAAATGT„ 5377,AA459692„20,111,TGACCACGAAATGTTTGTAG„

5378,AA459692„20,105,CGAAATGTTTGTAGTGAGAA„

5379,AA459692„20,99,GTTTGTAGTGAGAATATCAG„

5380,AA459692„20,93,AGTGAGAATATCAGGCAGGT„

5381,AA459692„20,87,AATATCAGGCAGGTGTCTGA„ 5382,AA459692„20,81,AGGCAGGTGTCTGATATTCC„

5383,AA459692„20,75,GTGTCTGATATTCCATGGTT„

5384,AA459692„20,69,GATATTCCATGGTTTACAGT„

5385,AA459692,,20,63,CCATGGTTTACAGTTTATTC„

5386,AA459692„20,57,TTTACAGTTTATTCCAGGCA„ 5387,AA459692„20,51,GTTTATTCCAGGCAGGTTTA„

5388,AA459692„20,45,TCCAGGCAGGTTTATGTTTC„

5389,AA459692„20,39,CAGGTTTATGTTTCCTTGCT„

5390,AA459692„20,33,TATGTTTCCTTGCTAATACA„

5391,AA459692,,20,27,TCCTTGCTAATACACGTACA„ 5392,AA459692„20,21 ,CTAATACACGTACAATTTTA„

5393,AA459692„20,15,CACGTACAATTTTACAACTA„

5394,AA459692„20,9,CAATTTTACAACTACTGTAT„

5395,AA459692„20,3,TACAACTACTGTATTAACAG„

(GENBANK ACCESSION NO. AA487557) TTTTCAAATTTTAATTAAAATCTTTATTGAATAAAAATGTTTCAGACTAGGTAAGACTAAGAAAGCAGAATGTTTTACATCTCTAAA

AAATATTAAAGCTAAATCTCTATAAATGCAGTACAAAGAAAAGCCTACAGCTTAAGACACCTCTCCCTCCCATCCATACAATTTGGA

ATATCAACTGTGTACAACAAATGTACTCAAGTTTATAATGTCCCCAAACCTTAAGACTAGAAAATCATCCCAAGAAAAAGGCCTAT

AGTTGGTTTAATTTCACCCTGAGAATACTGTGATAAAAATCAATATATTTCAGAGCTAGTAAGTATTTAAAAATTAGTGTCTCAAAA

AGGGGACATC (SEQ ID NO: 5396)

5397,AA487557„20,338,GATGTCCCCTTTTTGAGACA„

5398,AA487557,,20,332,CCCTTTTTGAGACACTAATT„

5399,AA487557„20,326,TTGAGACACTAATTTTTAAA„ 5400,AA487557„20,320,CACTAATTTTTAAATACTTA„

5401,AA487557„20,314,TTTTTAAATACTTACTAGCT„

5402,AA487557„20,308,AATACTTACTAGCTCTGAAA„

5403,AA487557„20,302,TACTAGCTCTGAAATATATT„

5404,AA487557„20,296,CTCTGAAATATATTGATTTT„ 5405,AA487557„20,290,AATATATTGATTTTTATCAC„

5406,AA487557„20,284,TTGATTTTTATCACAGTATT„

5407,AA487557„20,278,TTTATCACAGTATTCTCAGG„

5408,AA487557„20,272,ACAGTATTCTCAGGGTGAAA„

5409,AA487557„20,266,TTCTCAGGGTGAAATTAAAC„ 5410,AA487557„20,260,GGGTGAAATTAAACCAACTA„

5411,AA487557„20,254,AATTAAACCAACTATAGGCC„

5412,AA487557„20,248,ACCAACTATAGGCCTTTTTC„

5413,AA487557„20,242,TATAGGCCTTTTTCTTGGGA„

5414,AA487557„20,236,CCTTTTTCTTGGGATGATTT„ 5415,AA487557„20,230,TCTTGGGATGATTTTCTAGT„

5416,AA487557„20,224,GATGATTTTCTAGTCTTAAG„ ₍

5417,AA487557„20,218,TTTCTAGTCTTAAGGTTTGG„

5418,AA487557„20,212,GTCTTAAGGTTTGGGGACAT„

5419,AA487557„20,206,AGGTTTGGGGACATTATAAA„ 5420,AA487557„20,200,GGGGACATTATAAACTTGAG„

5421 ,AA487557„20, 194.ATTATAAACTTGAGTACATT,,

5422,AA487557„20,188,AACTTGAGTACATTTGTTGT„

₅423,AA487557„20,182,AGTACATTTGTTGTACACAG„

5424,AA487557„20,176,TTTGTTGTACACAGTTGATA„ 5425,AA487557„20, 170,GTACACAGTTGATATTCCAA„

5426,AA487557„20, 164.AGTTGATATTCCAAATTGTA,,

5427,AA487557„20, 158,TATTCCAAATTGTATGGATG„

5428,AA487557„20,152,AAATTGTATGGATGGGAGGG„

5429,AA487557„20,146,TATGGATGGGAGGGAGAGGT„ 5430,AA487557„20,140,TGGGAGGGAGAGGTGTCTTA„ 5431 ,AA487557„20, 134,GGAGAGGTGTCTTAAGCTGT„

5432,AA487557„20,128,GTGTCTTAAGCTGTAGGCTT„

5433,AA487557„20,122,TAAGCTGTAGGCTTTTCTTT„

5434,AA487557„20, 116,GTAGGCTTTTCTTTGTACTG„

5435,AA487557„20, 110.TTTTCTTTGTACTGCATTTA,,

5436,AA487557„20,104,TTGTACTGCATTTATAGAGA„

5437,AA487557„20,98,TGCATTTATAGAGATTTAGC„

5438,AA487557„20,92,TATAGAGATTTAGCTTTAAT„

5439,AA4875₅7„20,86,GATTTAGCTTTAATATTTTT„

5440,AA487557„20,80,GCTTTAATATTTTTTAGAGA„

5441,AA487557„20,74,ATATTTTTTAGAGATGTAAA„

5442,AA487557„20,68,TTTAGAGATGTAAAACATTC„

5443,AA487557„20,62,GATGTAAAACATTCTGCTTT„

5444,AA487557„20,56,AAACATTCTGCTTTCTTAGT„

544₅,AA487₅57„20,50,TCTGCTTTCTTAGTCTTACC„

5446,AA487557„20,44,TTCTTAGTCTTACCTAGTCT„

5447,AA487557„20,38,GTCTTACCTAGTCTGAAACA„

5448,AA487557„20,32,CCTAGTCTGAAACATTTTTA„

5449,AA487557„20,26,CTGAAACATTTTTATTCAAT„

5450,AA487557„20,20,CATTTTTATTCAATAAAGAT„

5451,AA487557„20,14,TATTCAATAAAGATTTTAAT„

₅4₅2,AA487557„20_S8,ATAAAGATTTTAATTAAAAT„

5453,AA487557„20,2,ATTTTAATTAAAATTTGAAA„

(GENBANK ACCESSION NO. T69168)

CAATAANGTGCNTTTCAACTCAGCAATATACATATCANTGCNTTTCCTCATTANTTAATTGATCCATCAATAAATATACAAAAACCA

GAGGAAGGGTGTGCTCTGAAAAGTCAAAGTAACAATAACAGTGGTCATTGTACAGCACAAGANTGAACAATGGGCTATTCTTTGAA

AACTCAAAACAAATGATTTACACAAAGACATATCTATAACATAAAGGTGAATGGACCATGTTATTCTTATTCTTANGTACATTTTGC

TTTTCCAGNTAAGTCAAATGTTTCCTCTCTCCTTACTCCTCTGATATTNCAGTNTTGAATGAATGTTGGCTACANAATCTNTTCT

(SEQ ID NO: 5454)

5455,T69168„20,326,AGAANAGATTNTGTAGCCAA„ 5456.T69168„20,320,GATTNTGTAGCCAACATTCA„ 5457,T69168„20,314,GTAGCCAACATTCATTCAAN„ 5458,T69168„20,308,AACATTCATTCAANACTGNA„ 5459,T69168„20,302,CATTCAANACTGNAATATCA„ 5460,T69168„20,296_JANACTGNAATATCAGAGGAG„ 5461,T69168„20,290,NAATATCAGAGGAGTAAGGA„ 5462,T69168„20,284,CAGAGGAGTAAGGAGAGAGG„ 5463,T69168„20,278,AGTAAGGAGAGAGGAAACAT„ 5464/T69168„20,272,GAGAGAGGAAACATTTGACT„ 5465.T69168„20,266,GGAAACATTTGACTTANCTG„ 5466.T69168„20,260,ATTTGACTTANCTGGAAAAG„ 5467.T69168„20,254,CTTANCTGGAAAAGCAAAAT„ 5468,T69168„20,248,TGGAAAAGCAAAATGTACNT„ 5469,T69168„20,242,AGCAAAATGTACNTAAGAAT„ 5470,T69168„20,236,ATGTACNTAAGAATAAGAAT„ 5471 ,T69168„20,230,NTAAGAATAAGAATAACATG„ 5472,T69168„20,224,ATAAGAATAACATGGTCCAT„ 5473,T69168„20,218,ATAACATGGTCCATTCACCT„ 5474,T69168„20,212,TGGTCCATTCACCTTTATGT„ 547₅,T69168„20,206,ATTCACCTTTATGTTATAGA„ ₅476,T69168„20,200,CTTTATGTTATAGATATGTC„ 5477,T69168„20, 194,GTTATAGATATGTCTTTGTG„ 5478.T69168„20, 188,GATATGTCTTTGTGTAAATC„ 5479.T69168„20, 182,TCTTTGTGTAAATCATTTGT„ 5480.T6916S„20, 176,TGTAAATCATTTGTTTTGAG„ 5481 ,T6916S„20, 170,TCATTTGTTTTGAGTTTTCA„ 5482.T69168„20, 164.GTTTTGAGTTTTCAAAGAAT,, 5483 ,T69168„20, 158,AGTTTTCAAAGAATAGCCCA„ 5484.T69168„20, 152,CAAAGAATAGCCCATTGTTC„ 5485,T69168„20,146,ATAGCCCATTGTTCANTCTT„ 5486.T69168„20, 140,CATTGTTCANTCTTGTGCTG„ 5487,T69168„20,134,TCANTCTTGTGCTGTACAAT„ 5488,T69168„20,128,TTGTGCTGTACAATGACCAC„ 5489,T69168„20,122,TGTACAATGACCACTGTTAT„ 5490.T69168„20, 116,ATGACCACTGTTATTGTTAC„ 5491 ,T69168„20, 110,ACTGTTATTGTTACTTTGAC„ ₅492,T69168„20, 104,ATTGTTACTTTGACTTTTCA„ ₅493,T69168„20,98,ACTTTGACTTTTCAGAGCAC„ ₅494,T69168„20,92,ACTTTTCAGAGCACACCCTT„ ₅495,T69168„20,86,CAGAGCACACCCTTCCTCTG„ 5496,T69168„20,80,ACACCCTTCCTCTGGTTTTT„ 5497,T69168„20,74,TTCCTCTGGTTTTTGTATAT„ 5498,T69168„20,68,TGGTTTTTGTATATTTATTG„ 5499.T69168„20,62,TTGTATATTTATTGATGGAT„ ₅₅00,T69168„20,56,ATTTATTGATGGATCAATTA„

5501 ,T69168„20,50,TGATGGATCAATTAANTAAT„

5502.T69168„20,44,ATCAATTAANTAATGAGGAA„

5503,T69168„20,38,TAANTAATGAGGAAANGCAN„ 5504,T69168„20,32,ATGAGGAAANGCANTGATAT„

5505,T69168„20,26,AAANGCANTGATATGTATAT„

5506,T69168„20,20,ANTGATATGTATATTGCTGA„ '

5507,T69168„20,14,ATGTATATTGCTGAGTTGAA„

5508,T69168„20,8,ATTGCTGAGTTGAAANGCAC„ 5509,T69168„20,2,GAGTTGAAANGCACNTTATT„

(GENBANK ACCESSION NO. AI313387)

CAATTCCCAGTCACCTTTATTTAAAGTATATTAAATAAATTATCTCAATATATACAAATAGAACAATATTACCTACATAAATAGAAA

ATCCCCATATAGAAAACCTTTTTAAAAAATTATATATACAATGTCAACCATAGAAGCTTTAAGTACCTTAAATCATAAACTCTGTAG

TTTGTATAGTAGTCTTATAAAAATATAGTTAGCTCTCAAATGTTTAATGCCACTTAAGTCAGTTAAAGTGCAGATTGTAAAGCATATT AGGAAGGTGCCCAGAATACCAATGTCTCCTGCACTTAACACATTAATACAAAGTTTGCCAATTGTTTTGAATTTCCAAATGTATTCC

TGAAAAAAAAAAGAACCTAAACACTATATTATAGACATATGTTAGAAAAGTCCTAGAAATGCACCCAATTTCCTTCCATTCTACTTT

CCTACATGGATTGAAGTCAGNCCCTCAAAAGCTTTTCGGGCTGGCAT

(SEQ ID NO: 5510) 5511 ,AI313387„20,464,ATGCCAGCCCGAAAAGCTTT„

5512,AI313387„20,458,GCCCGAAAAGCTTTTGAGGG„

5513,AI313387„20,452,AAAGCTTTTGAGGGNCTGAC„

5514.AI313387„20,446,TTTGAGGGNCTGACTTCAAT„

5515,AI313387„20,440,GGNCTGACTTCAATCCATGT„ 5516,AI313387„20,434,ACTTCAATCCATGTAGGAAA„

5517,AI313387„20,428,ATCCATGTAGGAAAGTAGAA„

5518,AI313387„20,422₎GTAGGAAAGTAGAATGGAAG„

5519,AI313387„20,416,AAGTAGAATGGAAGGAAATT„

5520,AI313387„20,410,AATGGAAGGAAATTGGGTGC„ 5521,AI313387„20,404,AGGAAATTGGGTGCATTTCT„

5522,AI313387„20,398,TTGGGTGCATTTCTAGGACT„

5523,AI313387„20,392,GCATTTCTAGGACTTTTCTA„

5524,AI313387„20,386_>CTAGGACTTTTCTAACATAT„

5525,AI313387„20,380₁CTTTTCTAACATATGTCTAT„ 5526,AI313387„20,374₁TAACATATGTCTATAATATA„

5527,AI313387„20,368₁ATGTCTATAATATAGTGTTT„

5528,AI313387„20,362 TAATATAGTGTTTAGGTTC„

5529,AI313387„20,356

5530,AI313387„20,350/ 5531 ,AI313387„20,344,TCTTTTTTTTTTCAGGAATA„

5₅32,AI313387„20,338₎TTTTTTCAGGAATACATTTG„

5533,AI313387„20,332,CAGGAATACATTTGGAAATT„

5534,AI313387„20,326,TACATTTGGAAATTCAAAAC„

5535₎AI313387„20,320,TGGAAATTCAAAACAATTGG„ 5536,AI313387„20,314,TTCAAAACAATTGGCAAACT„

5537,AI313387„20,308₎ACAATTGGCAAACTTTGTAT„

5₅38,AI313387„20,302,GGCAAACTTTGTATTAATGT„

5539,AI313387„20,296,CTTTGTATTAATGTGTTAAG„

5540,AI313387„20,290,ATTAATGTGTTAAGTGCAGG„ 5541,AI313387„20,284,GTGTTAAGTGCAGGAGACAT„

5542,AI313387„20,278,AGTGCAGGAGACATTGGTAT„

5543,AI313387„20,272,GGAGACATTGGTATTCTGGG„

5544,AI313387„20,266,ATTGGTATTCTGGGCACCTT„

5545,AI313387„20,260,ATTCTGGGCACCTTCCTAAT„ 5546,AI313387„20,254,GGCACCTTCCTAATATGCTT„

5547,AI313387„20,248,TTCCTAATATGCTTTACAAT„

5548,AI313387„20,242,ATATGCTTTACAATCTGCAC„

5549,AI313387„20,236,TTTACAATCTGCACTTTAAC„

5550,AI313387„20,230,ATCTGCACTTTAACTGACTT„ 5551,AI313387„20,224,ACTTTAACTGACTTAAGTGG„

5552,AI313387„20,218,ACTGACTTAAGTGGCATTAA„

5553,AI313387„20,212,TTAAGTGGCATTAAACATTT„

5554,AI313387„20,206,GGCATTAAACATTTGAGAGC„

5555,AI313387„20,200,AAACATTTGAGAGCTAACTA„ 5556.AI313387„20, 194,TTGAGAGCTAACTATATTTT„

5557,AI313387„20,1S8,GCTAACTATATTTTTATAAG„

5558,AI313387„20,182,TATATTTTTATAAGACTACT„

5559.AI313387„20, 176,TTTATAAGACTACTATACAA„

5560,AI313387„20,170,AGACTACTATACAAACTACA„ 5561,AI313387„20,164,CTATACAAACTACAGAGTTT„

5562,AI313387„20,1₅8,AAACTACAGAGTTTATGATT„

5563,AI313387„20,1₅2,CAGAGTTTATGATTTAAGGT„

5564,AI313387„20,146,TTATGATTTAAGGTACTTAA„

5565,AI313387„20,140,TTTAAGGTACTTAAAGCTTC„ 5566,AI313387..20, 134,GTACTTAAAGCTTCTATGGT„ 5567,AI313387„20,128,AAAGCTTCTATGGTTGACAT„

5568,AI313387„20,122,TCTATGGTTGACATTGTATA„

5569,AI313387„20,116,GTTGACATTGTATATATAAT„

5570,AI313387„20,110,ATTGTATATATAATTTTTTA„ 5571,AI313387„20,104,TATATAATTTTTTAAAAAGG„

5572,AI313387„20,98,ATTTTTTAAAAAGGTTTTCT„

5573,AI313387„20,92,TAAAAAGGTTTTCTATATGG„

5574,AI313387„20,86,GGTTTTCTATATGGGGATTT„

5575,AI313387„20,80,CTATATGGGGATTTTCTATT„ 5576,AI313387„20,74,GGGGATTTTCTATTTATGTA„

5577,AI313387„20,68,TTTCTATTTATGTAGGTAAT„

5578,AI313387„20,62,TTTATGTAGGTAATATTGTT„

5579,AI313387„20,56,TAGGTAATATTGTTCTATTT„

5₅80,AI313387„20,50,ATATTGTTCTATTTGTATAT„ 5581.AI313387„20,44,TTCTATTTGTATATATTGAG„

5582,AI313387„20,38,TTGTATATATTGAGATAATT„

₅₅83,AI313387,,20,32,ATATTGAGATAATTTATTTA„

5584,AI313387„20,26,AGATAATTTATTTAATATAC„

5585,AI313387„20,20,TTTATTTAATATACTTTAAA„ 5586,AI313387„20,14,TAATATACTTTAAATAAAGG„

5587,AI313387„20,8,ACTTTAAATAAAGGTGACTG„

5588,AI313387„20,2,AATAAAGGTGACTGGGAATT„

(GENBANK ACCESSION NO. AA909635)

GGGTATTTTTACATATTTATTAAAACAAGTTTCCTGAGAAGTTTGACTAGGCTATGTTGTTGTTAACCTAGTTTGCTTAAAATGTACG AAAATGCAATCAAACTTACATATCTTTTAAATATTCGAAAGTCAGATTTTGTTCTGATTGCCCTATCCAATTAGGGCAAATTAGTGA

GGGTTTTTTTGTTTTTTGTTTTGTTTTTCTAACAATAGTCTGAAACATAAAATTAAGTTTGTGTTTAAAAACAATTCTTGAAACTGTCA

TAAACATATGATATCTATTGATTAAACAGTAATAAAAAGACACAAGGTACAAGAATTGAGGCTTGGCTGTTCTGGCTGTATACTAAC

TTCATAT

(SEQ LD NO: 5₅89)

5590,AA909635„20,339,ATATGAAGTTAGTATACAGC„

5591,AA909635„20,333,AGTTAGTATACAGCCAGAAC„

5592,AA909635„20,327,TATACAGCCAGAACAGCCAA„

5593,AA909635„20,321,GCCAGAACAGCCAAGCCTCA„ 5594,AA909635„20,315,ACAGCCAAGCCTCAATTCTT„

5595,AA909635„20,309,AAGCCTCAATTCTTGTACCT„

5596,AA909635„20,303,CAATTCTTGTACCTTGTGTC„

5597,AA909635„20,297,TTGTACCTTGTGTCTTTTTA„

5598,AA909635„20,291,CTTGTGTCTTTTTATTACTG„ 5599,AA909635„20,285,TCTTTTTATTACTGTTTAAT„

5600,AA909635„20,279,TATTACTGTTTAATCAATAG„

5601,AA909635„20,273,TGTTTAATCAATAGATATCA„

5602,AA909635„20,267,ATCAATAGATATCATATGTT„

5603,AA909635„20,261,AGATATCATATGTTTATGAC„ 5604,AA909635„20,255,CATATGTTTATGACAGTTTC„

5605,AA909635„20,249,TTTATGACAGTTTCAAGAAT„

5606,AA909635„20,243,ACAGTTTCAAGAATTGTTTT„

5607,AA909635„20,237,TCAAGAATTGTTTTTAAACA„

5608,AA909635„20,231 ,ATTGTTTTTAAACACAAACT„ 5609,AA909635„20,225,TTTAAACACAAACTTAATTT„

5610,AA909635„20,219,CACAAACTTAATTTTATGTT„

5611 ,AA909635„20,213,CTTAATTTTATGTTTCAGAC„

5612,AA909635„20,207,TTTATGTTTCAGACTATTGT„

5613,AA909635„20,201,TTTCAGACTATTGTTAGAAA„ 5614,AA909635„20,195,ACTATTGTTAGAAAAACAAA„

5615,AA909635„20,189,GTTAGAAAAACAAAACAAAA„

5616,AA909635„20,183,AAAACAAAACAAAAAACAAA„

5617,AA909635„20,177,AAACAAAAAACAAAAAAACC„

5618,AA909635„20, 171 ,AAAACAAAAAAACCCTCACT„ 5619,AA909635„20, 165,AAAAAACCCTCACTAATTTG„

5620,AA909635„20,159,CCCTCACTAATTTGCCCTAA„

5621 ,AA909635„20, 153,CTAATTTGCCCTAATTGGAT„

5622,AA909635„20,147,TGCCCTAATTGGATAGGGCA„

5623,AA909635„20, 141 ,AATTGGATAGGGCAATCAGA„ 5624,AA909635„20,135,ATAGGGCAATCAGAACAAAA„

5625,AA909635„20,129,CAATCAGAACAAAATCTGAC„

5626,AA909635„20,123,GAACAAAATCTGACTTTCGA„

5627,AA909635„20,117,AATCTGACTTTCGAATATTT„

5628,AA909635„20,111,ACTTTCGAATATTTAAAAGA„ 5629,AA909635„20, 105,GAATATTTAAAAGATATGTA„

5630,AA909635„20,99,TTAAAAGATATGTAAGTTTG„

5631,AA909635„20,93,GATATGTAAGTTTGATTGCA„

5632,AA909635„20,87_STAAGTTTGATTGCATTTTCG„

5633,AA909635„20,81,TGATTGCATTTTCGTACATT„ 5634,AA909635„20,75,CATTTTCGTACATTTTAAGC„ 5635,AA909635„20,69,CGTACATTTTAAGCAAACTA„

5636,AA909635„20,63,TTTTAAGCAAACTAGGTTAA„

5637,AA909635„20,57,GCAAACTAGGTTAACAACAA„

5638,AA909635„20,51 ,TAGGTTAACAACAACATAGC„ 5639,AA909635„20,45,AACAACAACATAGCCTAGTC„

5640,AA909635„20,39,AACATAGCCTAGTCAAACTT„

5641,AA90963₅„20,33,GCCTAGTCAAACTTCTCAGG„

₅642,AA90963₅„20,27,TCAAACTTCTCAGGAAACTT„

5643,AA909635„20,21,TTCTCAGGAAACTTGTTTTA„ ₅644,AA90963₅„20, 15,GGAAACTTGTTTTAATAAAT„

5645,AA909635„20,9,TTGTTTTAATAAATATGTAA„

5646,AA909635„20,3,TAATAAATATGTAAAAATAC„

(GENBANK ACCESSION NO. R00103)

CGCTGCCAGGGTCCGCGGCGGCCCCCTCCTCGACAGCTGAGGGGGCAGCCTCTTCAGCCACCGGGGCTGGGGTCTGGGGNTGGCTC GGGGCTGGCCTCAGTAGGGGCCTCAGTGGGGCTTGGGGGTCTATGGGCTTCCTCCTCCTTCTCTAACATTGGGAAGCCGAGTGCTTC

TGAAGGTTCATCAGGGGACAGATCGGGGAGAGTTGGCTTAAAGGTGGCAGCATCACTGTCATCTCCAGTAGTCGGCTCCGGCACAA

GGTCTAGTNGGTNAGGTNAGAGATGGGATTAAGGGTTCCTNCCCAGATCTCAAAGGGCAGCTTNAGATNGGGGAGCCCCACACAC

GAAACTTCCATTTTATTTTAT

(SEQ LD NO: 5647)

5648,R00103„20,346,ATAAAATAAAATGGAAGTTT„

5649,R00103„20,340,TAAAATGGAAGTTTCGTGTG„

5650.R00103„20,334,GGAAGTTTCGTGTGTGGGGC„

5651 ,R00103„20,328,TTCGTGTGTGGGGCTCCCCN„ 56₅2,R00103„20,322,TGTGGGGCTCCCCNATCTNA„

5653,R00103„20,316,GCTCCCCNATCTNAAGCTGC„

5654,R00103„20,310,CNATCTNAAGCTGCCCTTTG„

5655,R00103„20,304,NAAGCTGCCCTTTGAGATCT„

5656,R00103„20,298,GCCCTTTGAGATCTGGGNAG„ 5657,R00103„20,292,TGAGATCTGGGNAGGAACCC„

5658,R00103„20,286,CTGGGNAGGAACCCTTAATC„

5659.R00103„20,280,AGGAACCCTTAATCCCATCT„

5660,R00103„20,274,CCTTAATCCCATCTCTNACC„

5661,R00103,,20,268,TCCCATCTCTNACCTNACCN„ 5662,R00103„20,262,CTCTNACCTNACCNACTAGA„

5663,R00103„20,256,CCTNACCNACTAGACCTTGT„

5664,R00103„20,250,CNACTAGACCTTGTGCCGGA„

5665.R00103„20,244,GACCTTGTGCCGGAGCCGAC„

5666,R00103„20,238,GTGCCGGAGCCGACTACTGG„ 5667,R00103„20,232,GAGCCGACTACTGGAGATGA„

5668,R00103„20,226,ACTACTGGAGATGACAGTGA„

5669,R00103„20,220,GGAGATGACAGTGATGCTGC„

5670,R00103„20,214,GACAGTGATGCTGCCACCTT„

5671 ,R00103„20,208,GATGCTGCCACCTTTAAGCC„ 5672,R00103„20,202,GCCACCTTTAAGCCAACTCT„

5673,R00103„20,196,TTTAAGCCAACTCTCCCCGA„

5674.RO0103„20, 190,CCAACTCTCCCCGATCTGTC„

5675,R00103„20, 184,CTCCCCGATCTGTCCCCTGA„

5676,R00103„20,178,GATCTGTCCCCTGATGAACC„ 5677,R00103„20,172,TCCCCTGATGAACCTTCAGA„

5678.R00103„20, 166,GATGAACCTTCAGAAGCACT„

5679.R00103„20, 160,CCTTCAGAAGCACTCGGCTT„

5680,R00103„20,154,GAAGCACTCGGCTTCCCAAT„

5681,R00103„20,148,CTCGGCTTCCCAATGTTAGA„ 5682,R00103„20,142,TTCCCAATGTTAGAGAAGGA„

5683,R00103„20, 136,ATGTTAGAGAAGGAGGAGGA„

5684,R00103„20, 130,GAGAAGGAGGAGGAAGCCCA„

5685,R00103„20,124,GAGGAGGAAGCCCATAGACC„

₅686,R00103„20,118,GAAGCCCATAGACCCCCAAG„ 5687,R00103„20,112,CATAGACCCCCAAGCCCCAC„

5688,R00103„20,106,CCCCCAAGCCCCACTGAGGC„

5689,R00103„20,100,AGCCCCACTGAGGCCCCTAC„

5690,R00103„20,94,ACTGAGGCCCCTACTGAGGC„

5691,R00103„20,88,GCCCCTACTGAGGCCAGCCC„ 5692,R00103„20,82,ACTGAGGCCAGCCCCGAGCC„

5693,R00103„20,76,GCCAGCCCCGAGCCANCCCC„

5694,R00103„20,70,CCCGAGCCANCCCCAGACCC„

5695,R00103„20,64,CCANCCCCAGACCCCAGCCC„

5696,R00103„20,58,CCAGACCCCAGCCCCGGTGG„ 5697,R00103„20,52,CCCAGCCCCGGTGGCTGAAG„

5698,R00103„20,46,CCCGGTGGCTGAAGAGGCTG„

5699,R00103„20,40,GGCTGAAGAGGCTGCCCCCT„

5700,R00103„20,34,AGAGGCTGCCCCCTCAGCTG„

5701 ,R00103„20,28,TGCCCCCTCAGCTGTCGAGG„ 5702.RO0103„20,22,CTCAGCTGTCGAGGAGGGGG„ 5703 ,R00103„20, 16,TGTCGAGGAGGGGGCCGCCG„

5704,R00103„20,10,GGAGGGGGCCGCCGCGGACC„

5705.R00103„20,4,GGCCGCCGCGGACCCTGGCA„

(GENBANK ACCESSION NO. N35316)

NGAGCTTATCTTCAATTTTATTGTTGGGAATCTACAATTGCAAAGTGGTTCAAAGTCATTTCTTATACCACTTCACAATACACACACA

GATTTAGGAAACTTAAAAAAAGTTCTTTAAAAAATTCTAATAGGATTTACCCTATTTTACTGGCCAAGTGTAAAAAATAAACCCTAA

ATGTGCCTTTCTCTAATTTTCCTTGTACAATCTTATTGACATTTTTTATAGCTAATCCATATATGCATAGAACCGAGGCTATTATTTTG

CTGCAACAACTTTTATAAAAAGGTTATGAAGTTTAAAAGTATATTTTCGTATCAAGAGTACTTAATATTTGTAAACACTAAGAAACA

AACATACTTCCTATCAAAACCTCTAGCTG

(SEQ LD NO: 5706)

5707,N35316_; ,,20,361 ,CAGCTAGAGGTTTTGATAGG„

5708.N35316 ._:„20,355,GAGGTTTTGATAGGAAGTAT„

5709,N35316 ι_:„20,349,TTGATAGGAAGTATGTTTGT„

5710,N35316 l_;„20,343,GGAAGTATGTTTGTTTCTTA„

5711.N35316 l_:„20,337,ATGTTTGTTTCTTAGTGTTT„

5712.N35316 l„20,331 ,GTTTCTTAGTGTTTACAAAT„

5713,N35316_; „20,325,TAGTGTTTACAAATATTAAG„

5714,N35316_; „20,319,TTACAAATATTAAGTACTCT„

5715.N35316 i_:„20,313,ATATTAAGTACTCTTGATAC„

5716,N35316_: „20,307,AGTACTCTTGATACGAAAAT„

5717.N35316 !_:„20,301,CTTGATACGAAAATATACTT„

5718,N35316 ;_:„20,295,ACGAAAATATACTTTTAAAC„

5719,N35316 ,_:,20,289,ATATACTTTTAAACTTCATA„

5720,N3531 „20,283,TTTTAAACTTCATAACCTTT„

5721.N35316, „20,277,ACTTCATAACCTTTTTATAA„

5722,N35316_;„20,271 ,TAACCTTTTTATAAAAGTTG„

5723,N35316_; „20,265,TTTTATAAAAGTTGTTGCAG„

5724.N35316 i_:„20,259,AAAAGTTGTTGCAGCAAAAT„

5725,N35316 ._;„20,253,TGTTGCAGCAAAATAATAGC„

5726.N35316 ._:„20,247,AGCAAAATAATAGCCTCGGT„

5727,N35316 i_;„20,241,ATAATAGCCTCGGTTCTATG„

5728,N35316 ._:„20,235,GCCTCGGTTCTATGCATATA„

5729.N35316 ι_:„20,229,GTTCTATGCATATATGGATT„

5730,N35316 ,_;,20,223,TGCATATATGGATTAGCTAT„

5731.N35316 ;,„20,217,TATGGATTAGCTATAAAAAA„

5732,N35316_; ,,20,21 l.TTAGCTATAAAAAATGTCAA,,

5733.N35316, „20,205,ATAAAAAATGTCAATAAGAT„

5734.N35316_: „20,199,AATGTCAATAAGATTGTACA„

5735.N35316, „20, 193 ,AATAAGATTGTACAAGGAAA„

5736.N35316, „20, 187,ATTGTACAAGGAAAATTAGA„

5737,N35316 „_: 20, 181 ,CAAGGAAAATTAGAGAAAGG„

5738,N35316_: „20,175,AAATTAGAGAAAGGCACATT„

5739,N35316_: „20,169,GAGAAAGGCACATTTAGGGT„

5740,N35316 i_:„20,163,GGCACATTTAGGGTTTATTT„

5741,N35316 i_;„20, 157,TTTAGGGTTTATTTTTTACA„

5742,N35316 ;_:„20, 151 ,GTTTATTTTTTACACTTGGC„

5743,N35316 :_;„20,145,TTTTTACACTTGGCCAGTAA„

5744,N35316 ._;,,20, 139,CACTTGGCCAGTAAAATAGG„

5745.N35316 :_:„20, 133,GCCAGTAAAATAGGGTAAAT„

5746,N35316 ._;„20,127,AAAATAGGGTAAATCCTATT„

5747,N35316 ■_:„20, 121 ,GGGTAAATCCTATTAGAATT„

5748,N35316 ._:,,20, 115.ATCCTATTAGAATTTTTTAA,,

5749.N35316 ;_:„20, 109,TTAGAATTTTTTAAAGAACT„

5750,N35316_: „20, 103,TTTTTTAAAGAACTTTTTTT„

5751.N35316, „20,97,AAAGAACTTTTTTTAAGTTT„

5752.N35316, „20,91,CTTTTTTTAAGTTTCCTAAA„

5753.N35316, „20,85,TTAAGTTTCCTAAATCTGTG„

5754.N35316, „20,79,TTCCTAAATCTGTGTGTGTA„

5755.N35316, „20,73,AATCTGTGTGTGTATTGTGA„

5756.N35316, „20,67,TGTGTGTATTGTGAAGTGGT„

5757.N35316, „20,61,TATTGTGAAGTGGTATAAGA„

5758,N35316 i,„20,55,GAAGTGGTATAAGAAATGAC„

5759.N35316 :„20,49,GTATAAGAAATGACTTTGAA„

5760,N35316_; „20,43,GAAATGACTTTGAACCACTT„

5761.N35316, „20,37,ACTTTGAACCACTTTGCAAT„

5762.N35316, ,,20,31 ,AACCACTTTGCAATTGTAGA„

5763.N35316 „20,25,TTTGCAATTGTAGATTCCCA„

5764.N35316_:„20,19,ATTGTAGATTCCCAACAATA„

5765,N35316_;„20,13,GATTCCCAACAATAAAATTG„

5766,N35316_; „20,7,CAACAATAAAATTGAAGATA„

5767,N35316 ..,,20, 1 ,TAAAATTGAAGATAAGCTCN„

( (GGEENNBBAANNKK ACCESSION NO. AA293300)

A AAACCAAGGTTAAAATTCTTCAGACTTTATTAAAAAATGACATAAAGTGCATCTTATTAAAAAATGTATAAAAACCACATAAATTCAGGGCCCC

TGTGCTGGGCAGTGTTGATATCCCTTAGAGTGGAGGAAGGTGAGGGATGGAGGGTGAACTGGGGACTGGGGAGAGGACCAGGGTG CAGTTAGTTCCTCGTGTTTGAGTTCAAAGATGGAGCGAGGGTGGATATGGTGGGAAGGGGCACACGGGTTCTCACGCAACAACGGA GGAAGGCAGGCGACAGTCTCTTCCCTGAATTCTGAGGGAAAGGCGTACATTGTCACGAAATCTCTCCTGAGCTCGCGCTGTCCTCTC (SEQ LD NO: 5768) 5769,AA293300„20,326,GAGAGGACAGCGCGAGCTCA„

5770,AA293300„20,320,ACAGCGCGAGCTCAGGAGAG„

5771 ,AA293300„20,314,CGAGCTCAGGAGAGATTTCG„

5772,AA293300„20,308,CAGGAGAGATTTCGTGACAA„

5773,AA293300„20,302,AGATTTCGTGACAATGTACG„ 5774,AA293300„20,296,CGTGACAATGTACGCCTTTC„

5775,AA293300„20,290,AATGTACGCCTTTCCCTCAG„

5776,AA293300„20,284,CGCCTTTCCCTCAGAATTCA„

5777,AA293300„20,278,TCCCTCAGAATTCAGGGAAG„

5778,AA293300„20,272,AGAATTCAGGGAAGAGACTG„ 5779,AA293300„20,266,CAGGGAAGAGACTGTCGCCT„

5780,AA293300„20,260,AGAGACTGTCGCCTGCCTTC„

5781,AA293300„20,254,TGTCGCCTGCCTTCCTCCGT„

5782,AA293300„20,248,CTGCCTTCCTCCGTTGTTGC„

5783,AA293300„20,242,TCCTCCGTTGTTGCGTGAGA„ 5784,AA293300„20,236,GTTGTTGCGTGAGAACCCGT„

5785,AA293300„20,230,GCGTGAGAACCCGTGTGCCC„

5786,AA293300„20,224,GAACCCGTGTGCCCCTTCCC„

5787,AA293300„20,218,GTGTGCCCCTTCCCACCATA„

5788,AA293300„20,212,CCCTTCCCACCATATCCACC„ 5789,AA293300„20,206,CCACCATATCCACCCTCGCT„

5790,AA293300„20,200,TATCCACCCTCGCTCCATCT„

5791 ,AA293300„20, 194,CCCTCGCTCCATCTTTGAAC„

5792,AA293300„20,188,CTCCATCTTTGAACTCAAAC„

5793,AA293300„20, 182,CTTTGAACTCAAACACGAGG„ 5794,AA293300„20,176,ACTCAAACACGAGGAACTAA„

5795,AA293300„20,170,ACACGAGGAACTAACTGCAC„

5796,AA293300„20,164,GGAACTAACTGCACCCTGGT„

5797,AA293300„20,158,AACTGCACCCTGGTCCTCTC„

5798,AA293300„20,152,ACCCTGGTCCTCTCCCCAGT„ 5799,AA293300„20,146,GTCCTCTCCCCAGTCCCCAG„

5800,AA293300„20,140,TCCCCAGTCCCCAGTTCACC„

5801,AA293300„20,134,GTCCCCAGTTCACCCTCCAT„

5802,AA293300„20,128,AGTTCACCCTCCATCCCTCA„

5803,AA293300„20,122,CCCTCCATCCCTCACCTTCC„ 5804,AA293300„20,116,ATCCCTCACCTTCCTCCACT„

5805,AA293300„20,110_;CACCTTCCTCCACTCTAAGG„

5806,AA293300„20,104,CCTCCACTCTAAGGGATATC„

5807,AA293300„20,98,CTCTAAGGGATATCAACACT„

5808,AA293300„20,92,GGGATATCAACACTGCCCAG„ 5809,AA293300„20,86,TCAACACTGCCCAGCACAGG„

5810,AA293300„20,80,CTGCCCAGCACAGGGGCCCT„

5811,AA293300„20,74,AGCACAGGGGCCCTGAATTT„

5812,AA293300„20,68,GGGGCCCTGAATTTATGTGG„

5813,AA293300„20,62,CTGAATTTATGTGGTTTTTA„ ₅814,AA293300„20,56,TTATGTGGTTTTTATACATT„

5815,AA293300„20,50,GGTTTTTATACATTTTTTAA„

5816,AA293300„20,44,TATACATTTTTTAATAAGAT„

5817,AA293300„20,38,TTTTTTAATAAGATGCACTT„

5818,AA293300„20,32,AATAAGATGCACTTTATGTC„ ₅819,AA293300„20,26,ATGCACTTTATGTCATTTTT„

5820,AA293300„20,20,TTTATGTCATTTTTTAATAA„

₅821,AA293300„20,14,TCATTTTTTAATAAAGTCTG„

5822,AA293300„20,8,TTTAATAAAGTCTGAAGAAT„

5823,AA293300„20,2,AAAGTCTGAAGAATTACTGT„ ( _τG_τE_τN_τB_τA_ττN_τK_χ A_ττC_τC_τE_τS_τS_τIO_τN_ττ N_τO_τ._G A_AA_C2_A7_G87_G6_A4)_{ACTGTTTTTATTCCAACCACCT}

TTTATCTTAAAAGTGAAATAATTCCAGGATGGTAGGGCGAGACCCTGTGATGGGTGAATTTACCTCACTTGATACCAAGGGCCCTTA ATACTCGGGGAAGTGGGACTTTGTCGACAAAGCCAGGACAATCCCCCTACCCCCACCCCACCCAGCAGTGATTAAAAACCCGTACG GTCACTTTCTATGTGATGGCTGTCTCCCTCTCACCAGACTGCATAGCGGTTGCAGATGAACATTTGGCACCTAGATGGGGGTCAAGG AGCTGGGGCTGTGATTCAGGGAAGATGCTGAGGGGGACTGGGAGTCTCTGTTTGAATCTTGAAGCAAGGGGTGA

(SEQ ID NO: 5824)

5825,AA278764„20,404,TCACCCCTTGCTTCAAGATT„

5826,AA278764„20,398,CTTGCTTCAAGATTCAAACA„ 5827,AA278764„20,392,TCAAGATTCAAACAGAGACT„

5828,AA278764„20,386,TTCAAACAGAGACTCCCAGT„

5829,AA278764„20,380,CAGAGACTCCCAGTCCCCCT„

5830,AA278764„20,374,CTCCCAGTCCCCCTCAGCAT„

5831,AA278764„20,368,GTCCCCCTCAGCATCTTCCC„ 5832,AA278764„20,362,CTCAGCATCTTCCCTGAATC„ 5833,AA278764„20,356,ATCTTCCCTGAATCACAGCC„

5834,AA278764„20,350,CCTGAATCACAGCCCCAGCT„

5835,AA278764„20,344,TCACAGCCCCAGCTCCTTGA„

5836,AA278764„20,338,CCCCAGCTCCTTGACCCCCA„ 5837,AA27S764„20,332,CTCCTTGACCCCCATCTAGG„

5838,AA278764„20,326,GACCCCCATCTAGGTGCCAA„

5839,AA278764„20,320,CATCTAGGTGCCAAATGTTC„

5840,AA278764„20,314,GGTGCCAAATGTTCATCTGC„

5841,AA278764„20,308,AAATGTTCATCTGCAACCGC„ 5842,AA278764„20,302,TCATCTGCAACCGCTATGCA„

5843,AA278764„20,296,GCAACCGCTATGCAGTCTGG„

5844,AA278764„20,290,GCTATGCAGTCTGGTGAGAG„

5845,AA278764„20,284,CAGTCTGGTGAGAGGGAGAC„

5846,AA278764„20,278,GGTGAGAGGGAGACAGCCAT„ 5847,AA278764„20,272,AGGGAGACAGCCATCACATA„

5848,AA278764„20,266,ACAGCCATCACATAGAAAGT„

5849,AA278764„20,260,ATCACATAGAAAGTGACCGT„

58₅0,AA278764„20,254,TAGAAAGTGACCGTACGGGT„

5851,AA278764„20,248,GTGACCGTACGGGTTTTTAA„ ₅8₅2,AA278764„20,242,GTACGGGTTTTTAATCACTG„

₅8₅3,AA278764„20,236,GTTTTTAATCACTGCTGGGT„

₅8₅4,AA278764„20,230,AATCACTGCTGGGTGGGGTG„

₅8₅₅,AA278764„20,224,TGCTGGGTGGGGTGGGGGTA„

5856,AA278764„20,218,GTGGGGTGGGGGTAGGGGGA„ 5857,AA278764„20,212,TGGGGGTAGGGGGATTGTCC„

5858,AA278764„20,206,TAGGGGGATTGTCCTGGCTT„

5859,AA278764„20,200,GATTGTCCTGGCTTTGTCGA„

5860,AA278764„20,194,CCTGGCTTTGTCGACAAAGT„

5861,AA278764„20,188,TTTGTCGACAAAGTCCCACT„ 5862,AA278764„20,182,GACAAAGTCCCACTTCCCCG„

5863,AA278764„20,176,GTCCCACTTCCCCGAGTATT„

5864,AA278764„20,170,CTTCCCCGAGTATTAAGGGC„

5865,AA278764„20, 164,CGAGTATTAAGGGCCCTTGG„

5866,AA278764„20,158,TTAAGGGCCCTTGGTATCAA„ 5867,AA278764„20, 152,GCCCTTGGTATCAAGTGAGG„

5868,AA278764„20,146,GGTATCAAGTGAGGTAAATT„

5869,AA278764,,20,140,AAGTGAGGTAAATTCACCCA„

5870,AA278764„20, 134,GGTAAATTCACCCATCACAG„

5871,AA278764„20,128,TTCACCCATCACAGGGTCTC„ 5872,AA278764„20,122,CATCACAGGGTCTCGCCCTA„

5873,AA278764„20,116,AGGGTCTCGCCCTACCATCC„

5874,AA278764„20,110,TCGCCCTACCATCCTGGAAT„

5875,AA278764„20,104,TACCATCCTGGAATTATTTC„

5876,AA278764„20,98,CCTGGAATTATTTCACTTTT„ 5877,AA278764„20,92,ATTATTTCACTTTTAAGATA„

5878,AA278764„20,86,TCACTTTTAAGATAAATGCA„

5879,AA278764„20,80,TTAAGATAAATGCACTATTT„

5880,AA278764„20,74,TAAATGCACTATTTCACTGT„

5881,AA278764„20,68,CACTATTTCACTGTTCGCCT„ 5882,AA278764„20,62,TTCACTGTTCGCCTCCCATT„

5883,AA278764„20,56,GTTCGCCTCCCATTCTAAGG„

5884,AA278764„20,50,CTCCCATTCTAAGGAGGTGA„

5885,AA278764„20,44,TTCTAAGGAGGTGAGGTGGT„

5886,AA278764„20,38,GGAGGTGAGGTGGTTGGAAT„ 5887,AA278764„20,32,GAGGTGGTTGGAATAAAAAC„

5888,AA278764„20,26,GTTGGAATAAAAACAGTTCC„

5889,AA278764„20,20,ATAAAAACAGTTCCTGTCAA„

5890,AA278764„20,14,ACAGTTCCTGTCAAAAAAAA„

5891 ,AA278764„20,8,CCTGTCAAAAAAAAAAAAAA„ 5892,AA278764„20,2,AAAAAAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. AA678160)

ACAATCCAAGTCCGCTTCCAAATAAAGTAAAAAGTATTAGTATGAAAAACCCTGGCTACAATAAATTAGAGACCATTTAATCCTGC AATCTTGGTCAAGTTCATATTTCCACCATAGCACATTAG (SEQ ID NO: 5893)

5894,AA678160„20, 195,CTAATGTGCTATGGTGGAAA„

5895,AA678160„20, 189,TGCTATGGTGGAAATATGAA„

5896,AA678160„20,183,GGTGGAAATATGAACTTGAC„ 5897,AA678160„20,177,AATATGAACTTGACCAAGAT„

5898.AA678160„20, 171 ,AACTTGACCAAGATTGCAGG„

5899.AA678160„20, 165,ACCAAGATTGCAGGATTAAA„

5900,AA678160„20, 159,ATTGCAGGATTAAATGGTCT„

5901 ,AA678160„20, 153,GGATTAAATGGTCTCTAATT„ 5902,AA67S160„20,147,AATGGTCTCTAATTTATTGT„ 5903,AA678160„20,141,CTCTAATTTATTGTAGCCAG„

5904,AA678160„20,135,TTTATTGTAGCCAGGGTTTT„

5905,AA678160„20,129,GTAGCCAGGGTTTTTCATAC„

5906,AA678160„20, 123,AGGGTTTTTCATACTAATAC„ 5907,AA678160„20,117,TTTCATACTAATACTTTTTA„

5908.AA678160„20, 111 ,ACTAATACTTTTTACTTTAT„

5909,AA678160„20,105,ACTTTTTACTTTATTTGGAA„

5910,AA678160„20,99,TACTTTATTTGGAAGCGGAC„

5911,AA678160„20,93,ATTTGGAAGCGGACTTGGAT„ 5912,AA678160„20,87,AAGCGGACTTGGATTGTACT„

5913,AA678160„20,81,ACTTGGATTGTACTAGGGCA„

5914,AA678160„20,75,ATTGTACTAGGGCAAATCTT„

5915,AA678160„20,69,CTAGGGCAAATCTTTAAAAA„

5916.AA678160„20,63,CAAATCTTTAAAAAAAGAAA„ 5917,AA678160„20,57,TTTAAAAAAAGAAACATTTA„

5918,AA678160„20,51 ,AAAAGAAACATTTACAATAA„

5919,AA678160„20,45,AACATTTACAATAATAGAGA„

5920,AA678160„20,39,TACAATAATAGAGAAAAAGA„

5921,AA678160„20,33,AATAGAGAAAAAGACTGTGG„ 5922,AA678160„20,27,GAAAAAGACTGTGGCCCCAT„

5923,AA678160„20,21,GACTGTGGCCCCATTAAAAA„

5924.AA678160„20, 15,GGCCCCATTAAAAAAATGCT„

5925,AA678160„20,9,ATTAAAAAAATGCTAAATTA„

5926,AA678160„20,3,AAAATGCTAAATTAAGATTG„ (GENBANK ACCESSION NO. R42770)

TTTTTTTTTTTGTAACTTAATCTTTTATTTGTTCATTAATAGAGCAATTTTGATGTGAAGACTAAAAACACACATTTCCTGTTTCTTTA

ATACTCAGTGTATACATTTTGCAGATTAAATTTAAATACGTATTTTGGACCAGTTATTTGATANAATTCCTTCAGACGTTGTTTTTCA

AACCATCATCATAAATTTAACATATCTGCATTTTCGGTAAGTNCTTCAAACCCCTAGTCAAGGGGAAANCTGTAAATCTAATGAATA

AGGANCTTCTCAGGGCAATTAGGACAATATTTNCAAACNGGGCTGCTTGACTCANGGGTGACTTCCTTAAATCCGNGGTTTCTCAGG CCCCGNCACTGTGGGATGTTTTGAGCGGGGTAATTNTTTGTTATGGGGGGGCTGTCCCTACANCGGGGTTTTAGGGGGG

(SEQ ID NO: 5927)

5928,R42770„20,411,CCCCCCTAAAACCCCGNTGT„

5929,R42770„20,405,TAAAACCCCGNTGTAGGGAC„ 5930,R42770„20,399,CCCGNTGTAGGGACAGCCCC„

5931,R42770„20,393,GTAGGGACAGCCCCCCCATA„

5932,R42770„20,387,ACAGCCCCCCCATAACAAAN„

5933,R42770„20,381,CCCCCATAACAAANAATTAC„

5934,R42770„20,375,TAACAAANAATTACCCCGCT„ ₅93₅,R42770„20,369,ANAATTACCCCGCTCAAAAC„

5936,R42770„20,363,ACCCCGCTCAAAACATCCCA„

5937,R42770„20,357,CTCAAAACATCCCACAGTGN„

5938,R42770„20,351,ACATCCCACAGTGNCGGGGC„

5939,R42770„20,345,CACAGTGNCGGGGCCTGAGA„ 5940,R42770„20,339,GNCGGGGCCTGAGAAACCNC„

5941,R42770„20,333,GCCTGAGAAACCNCGGATTT„

5942,R42770„20,327,GAAACCNCGGATTTAAGGAA„

5943,R42770„20,321,NCGGATTTAAGGAAGTCACC„

5944,R42770„20,315.TTAAGGAAGTCACCCNTGAG,, 5945,R42770„20,309,AAGTCACCCNTGAGTCAAGC„

5946,R42770„20,303,CCCNTGAGTCAAGCAGCCCN„

5947,R42770„20,297,AGTCAAGCAGCCCNGTTTGN„

5948,R42770„20,291,GCAGCCCNGTTTGNAAATAT„

5949,R42770„20,285,CNGTTTGNAAATATTGTCCT„ 5950,R42770,,20,279,GNAAATATTGTCCTAATTGC„

5951,R42770„20,273,ATTGTCCTAATTGCCCTGAG„

5952,R42770„20,267,CTAATTGCCCTGAGAAGNTC„

5953,R42770„20,261 ,GCCCTGAGAAGNTCCTTATT„

5954,R42770„20,255,AGAAGNTCCTTATTCATTAG„ 5955,R42770„20,249,TCCTTATTCATTAGATTTAC„

5956,R42770„20,243,TTCATTAGATTTACAGNTTT„

5957,R42770„20,237,AGATTTACAGNTTTCCCCTT„

59₅8,R42770„20,231,ACAGNTTTCCCCTTGACTAG„

₅9₅9,R42770„20,225,TTCCCCTTGACTAGGGGTTT„ ₅960,R42770„20,219,TTGACTAGGGGTTTGAAGNA„

₅961 ,R42770„20,213,AGGGGTTTGAAGNACTTACC„

₅962,R42770„20,207,TTGAAGNACTTACCGAAAAT„

₅963,R42770„20,201 ,NACTTACCGAAAATGCAGAT„

₅964,R42770„20, 19₅,CCGAAAATGCAGATATGTTA„ ₅96₅,R42770„20, 189,ATGCAGATATGTTAAATTTA„

5966,R42770„20,183,ATATGTTAAATTTATGATGA„

5967,R42770„20,177,TAAATTTATGATGATGGTTT„

5968,R42770„20, 171 ,TATGATGATGGTTTGAAAAA„

5969,R42770„20, 165,GATGGTTTGAAAAACAACGT„ 5970,R42770„20, 159,TTGAAAAACAACGTCTGAAG„ 5971,R42770„20,153,AACAACGTCTGAAGGAATTN„

5972,R42770„20,147,GTCTGAAGGAATTNTATCAA„

5973,R42770„20,141,AGGAATTNTATCAAATAACT„

5974,R42770„20,135,TNTATCAAATAACTGGTCCA„ 5975,R42770„20,129,AAATAACTGGTCCAAAATAC„

5976,R42770„20,123,CTGGTCCAAAATACGTATTT„

5977,R42770„20,117,CAAAATACGTATTTAAATTT„

5978,R42770„20,111,ACGTATTTAAATTTAATCTG„

5979,R42770„20,105,TTAAATTTAATCTGCAAAAT„ 5980,R42770„20,99,TTAATCTGCAAAATGTATAC„

5981,R42770„20,93,TGCAAAATGTATACACTGAG„

5982,R42770„20,87,ATGTATACACTGAGTATTAA„

5983,R42770„20,81,ACACTGAGTATTAAAGAAAC„

5984,R42770„20,75,AGTATTAAAGAAACAGGAAA„ 5985,R42770„20,69,AAAGAAACAGGAAATGTGTG„

5986,R42770„20,63,ACAGGAAATGTGTGTTTTTA„

5987,R42770„20,57,AATGTGTGTTTTTAGTCTTC„

5988,R42770„20,51,TGTTTTTAGTCTTCACATCA„

₅989,R42770„20,45,TAGTCTTCACATCAAAATTG„ ₅990,R42770„20,39,TCACATCAAAATTGCTCTAT„

₅991,R42770„20,33,CAAAATTGCTCTATTAATGA„

₅992,R42770„20,27,TGCTCTATTAATGAACAAAT„

5993,R42770„20,21,ATTAATGAACAAATAAAAGA„

5994,R42770„20, 15,GAACAAATAAAAGATTAAGT„ 5995,R42770„20,9,ATAAAAGATTAAGTTACAAA„

5996,R42770„20,3,GATTAAGTTACAAAAAAAAA„

(GENBANK ACCESSION NO. H93087)

AAAACAAAATTCTGCATTTTTATAAAACTTGATAAAAAATAGTATTTCAAACTGTACAGTCACCAGAAGTACACAGTTATCAAAAAT

GCACACACTTCACTTGGCATCTCCAGCACCTTCAGCTTTCTGTGCCTGGTCTGTTTTGGCATCTCCATTTTCTGCAGGGTTATTCCCCT CCTTGCCAGCATCAGCTTTTCCCTTTTTCCCTTTGGGTACCTTCTCTCCCTTCTTTGCAGGGGCCTTTTTAGGCTTGGGCTCTGGCTTT

GGAGGAGCAGGTTTCTTTTTTTGGCAGGAAGAGAGGAAAAAGTGAACATCAGTACAATGGACTGAAGAAAACCACCCACAACCAA

CCAAAAGTACCAAGGGTAAGAGAAGTTTCTCCTCCTCCTCAAAAGTTTTTGGTGGTTGGCTTTCTTCTAGAATGTTGGATTTCCAGAA

GCCCACTCAAATGTCCCACTTTGGCTACAGGCATCAGAAATTTCAGAACCAGCNAAACCCCAAGGGGCAAGAGTCCCAAGTAGAGG

CAATGATTCCAAACCAGGCACTAACCATAATTCATGGGAAGCCAAGGGAATGGTTTTTGGANGGTTTTTAGGTTCAGGNCAAG (SEQ ID NO: 5997)

5998,H93087„20,5S8,CTTGNCCTGAACCTAAAAAC„

5999,H93087„20,582,CTGAACCTAAAAACCNTCCA„

6000,H93087„20,576,CTAAAAACCNTCCAAAAACC„ 6001 ,H93087„20,570, ACCNTCCAAAAACCATTCCC,,

6002,H93087„20,564,CAAAAACCATTCCCTTGGCT„

6003,H93087„20,₅₅8,CCATTCCCTTGGCTTCCCAT„

6004,H93087„20,₅₅2,CCTTGGCTTCCCATGAATTA„

600₅,H93087„20,546,CTTCCCATGAATTATGGTTA„ 6006,H93087„20,540,ATGAATTATGGTTAGTGCCT„

6007,H93087„20,534,TATGGTTAGTGCCTGGTTTG„

6008,H93087„20,528,TAGTGCCTGGTTTGGAATCA„

6009,H93087„20,522,CTGGTTTGGAATCATTGCCT„

6010,H93087„20,516,TGGAATCATTGCCTCTACTT„ 6011,H93087„20,510,CATTGCCTCTACTTGGGACT„

6012,H93087„20,504,CTCTACTTGGGACTCTTGCC„

6013,H93087„20,498,TTGGGACTCTTGCCCCTTGG„

6014,H93087„20,492,CTCTTGCCCCTTGGGGTTTN„

6015,H93087„20,486,CCCCTTGGGGTTTNGCTGGT„ 6016,H93087„20,480,GGGGTTTNGCTGGTTCTGAA„

6017,H93087„20,474,TNGCTGGTTCTGAAATTTCT„

6018,H93087„20,468,GTTCTGAAATTTCTGATGCC„

6019,H93087„20,462,AAATTTCTGATGCCTGTAGC„

6020,H93087„20,456,CTGATGCCTGTAGCCAAAGT„ 6021 ,H93087„20,4₅0,CCTGTAGCCAAAGTGGGACA„

6022,H93087„20,444,GCCAAAGTGGGACATTTGAG„

6023,H93087„20,438,GTGGGACATTTGAGTGGGCT„

6024,H93087„20,432,CATTTGAGTGGGCTTCTGGA„

6025,H93087„20,426,AGTGGGCTTCTGGAAATCCA„ 6026,H93087„20,420,CTTCTGGAAATCCAACATTC„

6027,H93087„20,414,GAAATCCAACATTCTAGAAG„

6028,H93087„20,40S,CAACATTCTAGAAGAAAGCC„

6029,H93087„20,402,TCTAGAAGAAAGCCAACCAC„

6030,H93087„20,396,AGAAAGCCAACCACCAAAAA„ 6031 ,H93087„20,390,CCAACCACCAAAAACTTTTG„

6032,H93087„20,384,ACCAAAAACTTTTGAGGAGG„

6033,H93087„20,378,AACTTTTGAGGAGGAGGAGA„

6034,H93087„20,372,TGAGGAGGAGGAGAAACTTC„

6035,H93087„20,366,GGAGGAGAAACTTCTCTTAC„ 6036,H93087„20,360,GAAACTTCTCTTACCCTTGG„ 6037,H93087„20,354,TCTCTTACCCTTGGTACTTT„

6038,H93087„20,348,ACCCTTGGTACTTTTGGTTG„

6039,H93087„20,342,GGTACTTTTGGTTGGTTGTG„

6040,H93087„20,336,TTTGGTTGGTTGTGGGTGGT„ 6041,H93087„20,330,TGGTTGTGGGTGGTTTTCTT„

6042,H93087„20,324,TGGGTGGTTTTCTTCAGTCC„

6043,H93087„20,318.GTTTTCTTCAGTCCATTGTA,,

6044,H93087„20,312,TTCAGTCCATTGTACTGATG„

6045,H93087„20,306,CCATTGTACTGATGTTCACT„ 6046,H93087„20,300,TACTGATGTTCACTTTTTCC„

6047,H93087„20,294,TGTTCACTTTTTCCTCTCTT„

6048,H93087„20,288,CTTTTTCCTCTCTTCCTGCC„

6049,H93087„20,282,CCTCTCTTCCTGCCAAAAAA„

6050,H93087„20,276,TTCCTGCCAAAAAAAGAAAC„ 6051,H93087„20,270,CCAAAAAAAGAAACCTGCTC„

60₅2,H93087„20,264,AAAGAAACCTGCTCCTCCAA„

6053,H93087„20,258,ACCTGCTCCTCCAAAGCCAG,,

6054,H93087„20,252,TCCTCCAAAGCCAGAGCCCA„

6055,H93087„20,246,AAAGCCAGAGCCCAAGCCTA„. 6056,H93087„20,240,AGAGCCCAAGCCTAAAAAGG„

6057,H93087„20,234,CAAGCCTAAAAAGGCCCCTG„

60₅8,H93087„20,228,TAAAAAGGCCCCTGCAAAGA„

60₅9,H93087„20,222,GGCCCCTGCAAAGAAGGGAG„

6060,H93087„20,216,TGCAAAGAAGGGAGAGAAGG„ 6061 ,H93087„20,210,GAAGGGAGAGAAGGTACCCA„

6062,H93087„20,204,AGAGAAGGTACCCAAAGGGA„

6063,H93087„20,198,GGTACCCAAAGGGAAAAAGG„

6064,H93087„20, 192,CAAAGGGAAAAAGGGAAAAG„

6065,H93087„20,186,GAAAAAGGGAAAAGCTGATG„ 6066,H93087„20, 180,GGGAAAAGCTGATGCTGGCA„

6067,H93087„20,174,AGCTGATGCTGGCAAGGAGG„

6068,H93087„20,168,TGCTGGCAAGGAGGGGAATA„

6069,H93087„20,162,CAAGGAGGGGAATAACCCTG„

6070,H93087„20, 156,GGGGAATAACCCTGCAGAAA„ 6071 ,H93087„20, 150,TAACCCTGCAGAAAATGGAG„

6072,H93087„20,144,TGCAGAAAATGGAGATGCCA„

6073,H93087„20,138,AAATGGAGATGCCAAAACAG„

6074,H93087„20, 132,AGATGCCAAAACAGACCAGG„

6075,H93087„20,126,CAAAACAGACCAGGCACAGA„ 6076,H93087„20, 120,AGACCAGGCACAGAAAGCTG„

6077,H93087„20, 114,GGCACAGAAAGCTGAAGGTG„

6078,H93087„20,108,GAAAGCTGAAGGTGCTGGAG„

6079,H93087„20,102,TGAAGGTGCTGGAGATGCCA„

6080,H93087„20,96,TGCTGGAGATGCCAAGTGAA„ 6081,H93087„20,90,AGATGCCAAGTGAAGTGTGT„

6082,H93087„20,84,CAAGTGAAGTGTGTGCATTT„

6083,H93087„20,78,AAGTGTGTGCATTTTTGATA„

6084,H93087„20,72,GTGCATTTTTGATAACTGTG„

6085,H93087„20,66,TTTTGATAACTGTGTACTTC„ 6086,H93087„20,60,TAACTGTGTACTTCTGGTGA„

6087,H93087„20,54,TGTACTTCTGGTGACTGTAC„

6088,H93087„20,48,TCTGGTGACTGTACAGTTTG„

6089,H93087„20,42,GACTGTACAGTTTGAAATAC„

6090,H93087„20,36,ACAGTTTGAAATACTATTTT„ 6091,H93087„20,30,TGAAATACTATTTTTTATCA„

6092,H93087„20,24,ACTATTTTTTATCAAGTTTT„

6093,H93087„20,18,TTTTATCAAGTTTTATAAAA„

6094,H93087„20, 12,CAAGTTTTATAAAAATGCAG„

6095,H93087„20,6,TTATAAAAATGCAGAATTTT„ (GENBANK ACCESSION NO. AA486518)

GAAGATGAAGGTGTCTCTCAGAGGAAGTTTCTGGATGGCAACGAGCTCACCCTGGCTGACTGCAACCTGTTGCCAAAGTTACACAT

AGTACAGGTGGTGTGTAAGAAGTACCGGGGATTCACCATCCCCGAGGCCTTCCGGGGAGTGCATCGGTACTTGAGCAATGCCTACG

CCCGGGAAGAATTCGCTTCCACCTGTCCAGATGATGAGGAGATCGAGCTCGCCTATGAGCAAGTGGCAAAGGCCCTCAAATAAGCC

CCTCCTGGGACTCCCTCAACCCCCTCCATTTTCTCCACAAAGGCCCTGGTGGTTTCCACATTGCTACCCAATGGACACACTCCAAAA TGGCCAGTGGGCAGGGAATCCTGGAGCACTTGTTCCGGGATGGTGTGGTGGAAGAGGGGATGAGGGAAAGAAATGGGGGGCCTGG

GTCAGATTTTTATTGTGGGGTGGGATGAGTAGGACAACATATTTCAGTAATAAAATACAGAATAAAAATC

(SEQ ID NO: 6096)

6097.AA486518„20,48 l.GATTTTTATTCTGTATTTTA,, 6098.AA486518„20,475,TATTCTGTATTTTATTACTG„

6099.AA486518„20,469,GTATTTTATTACTGAAATAT„

6100,AA486518„20,463,TATTACTGAAATATGTTGTC„

6101,AA486518„20,457,TGAAATATGTTGTCCTACTC„

6102.AA486518„20,45 l.ATGTTGTCCTACTCATCCCA,, 6103,AA486518„20,445,TCCTACTCATCCCACCCCAC„ 6104,AA486518„20,439,TCATCCCACCCCACAATAAA„ 6105,AA486518„20,433,CACCCCACAATAAAAATCTG„ 6106,AA486518„20,427,ACAATAAAAATCTGACCCAG„ 6107,AA486₅18„20,421 ,AAAATCTGACCCAGGCCCCC„ 6108,AA486₅18„20,415,TGACCCAGGCCCCCCATTTC„

6109,AA486518„20,409,AGGCCCCCCATTTCTTTCCC„ 6110,AA486518„20,403,CCCATTTCTTTCCCTCATCC„ 6111,AA486518„20,397,TCTTTCCCTCATCCCCTCTT„ 6112,AA486518„20,391,CCTCATCCCCTCTTCCACCA„ 6113₎AA486518„20,385,CCCCTCTTCCACCACACCAT„

6114,AA486518„20,379,TTCCACCACACCATCCCGGA„ 6115,AA486518„20,373,CACACCATCCCGGAACAAGT„ 6116,AA486518„20,367,ATCCCGGAACAAGTGCTCCA„ 6117,AA486518„20,361,GAACAAGTGCTCCAGGATTC„ 6118,AA486518„20,355,GTGCTCCAGGATTCCCTGCC„

6119,AA486518„20,349,CAGGATTCCCTGCCCACTGG„ 6120,AA486518„20,343,TCCCTGCCCACTGGCCATTT„ 6121 ,AA486518„20,337,CCCACTGGCCATTTTGGAGT„ 6122.AA486518„20,331,GGCCATTTTGGAGTGTGTCC„ 6123,AA486518„20,325,TTTGGAGTGTGTCCATTGGG„

6124.AA486518„20,319,GTGTGTCCATTGGGTAGCAA„ 6125,AA48651 S„20,313,CCATTGGGTAGCAATGTGGA„ 6126.AA486518„20,307,GGTAGCAATGTGGAAACCAC„ 6127,AA486518„20,301 ,AATGTGGAAACCACCAGGGC„ 6128,AA486518„20,295,GAAACCACCAGGGCCTTTGT„

6129,AA486518„20,289,ACCAGGGCCTTTGTGGAGAA„ 6130,AA486518„20,283,GCCTTTGTGGAGAAAATGGA„ 6131 ,AA486518„20,277,GTGGAGAAAATGGAGGGGGT„ 6132,AA486518„20,271.AAAATGGAGGGGGTTGAGGG,, 6133.AA486518„20,265,GAGGGGGTTGAGGGAGTCCC„

6134,AA486518„20,259,GTTGAGGGAGTCCCAGGAGG„ 6135,AA486518„20,2₅3,GGAGTCCCAGGAGGGGCTTA„ 6136,AA486518„20,247,CCAGGAGGGGCTTATTTGAG„ 6137.AA486518„20,24I ,GGGGCTTATTTGAGGGCCTT„ 6138,AA486518„20,235,TATTTGAGGGCCTTTGCCAC„

6139,AA486₅18„20,229,AGGGCCTTTGCCACTTGCTC„ 6140,AA486₅18„20,223,TTTGCCACTTGCTCATAGGC„ 6141 ,AA486₅18„20,217,ACTTGCTCATAGGCGAGCTC„ 6142,AA486₅18„20,211 ,TCATAGGCGAGCTCGATCTC„ 6143,AA486₅18„20,205,GCGAGCTCGATCTCCTCATC„

6144,AA486₅18„20, 199,TCGATCTCCTCATCATCTGG„ 6145,AA486518„20, 193,TCCTCATCATCTGGACAGGT„ 6146,AA486518„20,187,TCATCTGGACAGGTGGAAGC„ 6147,AA486518„20, 181 ,GGACAGGTGGAAGCGAATTC„ 6148.AA486518„20, 175,GTGGAAGCGAATTCTTCCCG„

6149,AA486518„20, 169,GCGAATTCTTCCCGGGCGTA„ 6150,AA486518„20, 163,TCTTCCCGGGCGTAGGCATT„ 6151 ,AA486518„20, 157.CGGGCGTAGGCATTGCTCAA,, 6152,AA486518„20, 151 ,TAGGCATTGCTCAAGTACCG„ 6153,AA486518„20, 145,TTGCTCAAGTACCGATGCAC„

6154,AA486518„20, 139.AAGTACCGATGCACTCCCCG,, 6155,AA486518„20, 133,CGATGCACTCCCCGGAAGGC„ 6156.AA486518„20, 127,ACTCCCCGGAAGGCCTCGGG„ 6157,AA486518„20, 121 ,CGGAAGGCCTCGGGGATGGT„ 6158,AA486518„20, 115,GCCTCGGGGATGGTGAATCC„

6159,AA486518„20,109,GGGATGGTGAATCCCCGGTA„ 6160,AA486518„20,103,GTGAATCCCCGGTACTTCTT„ 6161,AA486518„20,97,CCCCGGTACTTCTTACACAC„ 6162,AA486518„20,91 ,TACTTCTTACACACCACCTG„ 6163,AA486₅18„20,85,TTACACACCACCTGTACTAT„

6164,AA486₅18„20,79,ACCACCTGTACTATGTGTAA„ 6165,AA486518„20,73,TGTACTATGTGTAACTTTGG„ 6166,AA486518„20,67,ATGTGTAACTTTGGCAACAG„ 6167,AA486518„20,61 ,AACTTTGGCAACAGGTTGCA„ 6168,AA486518„20,55,GGCAACAGGTTGCAGTCAGC„

6169.AA486518„20,49,AGGTTGCAGTCAGCCAGGGT„ 6170,AA48651S„20,43,CAGTCAGCCAGGGTGAGCTC„ 6171 ,AA486518„20,37,GCCAGGGTGAGCTCGTTGCC„ 6172.AA486518„20,31 ,GTGAGCTCGTTGCCATCCAG„ 6173.AA486518„20,25,TCGTTGCCATCCAGAAACTT„

6174,AA486₅18„20,19,CCATCCAGAAACTTCCTCTG„ 6175,AA486518„20,13,AGAAACTTCCTCTGAGAGAC„ 6176,AA486₅18„20,7,TTCCTCTGAGAGACACCTTC„ 6177,AA486₅18„20,1,TGAGAGACACCTTCATCTTC„ (GENBANK ACCESSION NO. AA464729) TCTGCTTTTCCAACTTTATTTAGAAAAACAAATCCAGGTCCCATGGCCAAGAAGCATGCTGGCGAGCGCGATAAGAAGCTGGCGGC

CAAGAAAAAGACGGACAAGAAGCGGGCGCTGCGGGGCTGTAGTGGGCTCTCTTCCTCCTTCCACCGTGACCCCAACCTCTCCTGTC

CCCTCCCTCCAACTCTGTCTCTAAGTT

(SEQ ID NO: 6178)

6179,AA464729„20, 180,AACTTAGAGACAGAGTTGGA„

6180,AA464729„20,174,GAGACAGAGTTGGAGGGAGG„

6181 ,AA464729„20, 168,GAGTTGGAGGGAGGGGACAG„

6182,AA464729„20,162,GAGGGAGGGGACAGGAGAGG„ 6183,AA464729„20, 156,GGGGACAGGAGAGGTTGGGG„

6184,AA464729„20,150,AGGAGAGGTTGGGGTCACGG„

6185,AA464729„20,144,GGTTGGGGTCACGGTGGAAG„

6186,AA464729„20,138,GGTCACGGTGGAAGGAGGAA„

6187,AA464729„20,132,GGTGGAAGGAGGAAGAGAGC„ 6188,AA464729„20,126,AGGAGGAAGAGAGCCCACTA„

6189,AA464729„20,120,AAGAGAGCCCACTACAGCCC„

6190,AA464729„20,114,GCCCACTACAGCCCCGCAGC„

6191 ,AA464729„20, 108,TACAGCCCCGCAGCGCCCGC„

6192,AA464729„20, 102,CCCGCAGCGCCCGCTTCTTG„ 6193,AA464729„20,96,GCGCCCGCTTCTTGTCCGTC„

6194,AA464729„20,90,GCTTCTTGTCCGTCTTTTTC„

6195,AA464729„20,84,TGTCCGTCTTTTTCTTGGCC„

6196,AA464729„20,78,TCTTTTTCTTGGCCGCCAGC„

6197,AA464729„20,72,TCTTGGCCGCCAGCTTCTTA„ 6198,AA464729„20,66,CCGCCAGCTTCTTATCGCGC„

6199,AA464729„20,60,GCTTCTTATCGCGCTCGCCA„

6200,AA464729„20,54,TATCGCGCTCGCCAGCATGC„

6201 ,AA464729„20,48,GCTCGCCAGCATGCTTCTTG„

6202,AA464729„20,42,CAGCATGCTTCTTGGCCATG„ 6203,AA464729„20,36,GCTTCTTGGCCATGGGACCT„

6204,AA464729„20,30,TGGCCATGGGACCTGGATTT„

620₅,AA464729„20,24,TGGGACCTGGATTTGTTTTT„

6206,AA464729„20, 18,CTGGATTTGTTTTTCTAAAT„

6207,AA464729„20,12,TTGTTTTTCTAAATAAAGTT„ 6208,AA464729„20,6,TTCTAAATAAAGTTGGAAAA„

(GENBANK ACCESSION NO. AA180912)

GTGGTCGAGCCCTACAACTCTATCCTGACCACCCACACCACCCTGGAGCACTCAGACTGTGCCTTCATGGTGGACAACGAAGCAAT

CTATGACATCTGCCGCCGCAACCTAGACATCGAGCGCCCAACCTACACCAACCTCAATCGCCTCATTAGCCAAATTGTCTCCTCCAT

CACAGCTTCTCTGCGCTTTGACGGGGCCCTCAATGTGGACCTGACAGAGTTCCAGACCAACCTGGTGCCCTACCCTCGCATCCACTT CCCCCTGGCCACCTATGCACCAGTCATCTCTGCAGAAAAGGCATACCACGAGCAGCTGTCGGTGGCAGAGATCACCAATGCCTGCT

TTTGAGCCTNCCAACCAGANGGTAAAGTGTGATTCCCGG

(SEQ ID NO: 6209)

6210.AA180912„20,366,CCGGGAATCACACTTTACCN„ 6211,AA180912„20,360,ATCACACTTTACCNTCTGGT„

6212,AA180912„20,354,CTTTACCNTCTGGTTGGNAG„

6213,AA180912„20,348,CNTCTGGTTGGNAGGCTCAA„

6214,AA180912„20,342,GTTGGNAGGCTCAAAAGCAG„

6215,AA180912„20,336,AGGCTCAAAAGCAGGCATTG„ 6216,AA180912„20,330,AAAAGCAGGCATTGGTGATC„

6217,AA180912„20,324,AGGCATTGGTGATCTCTGCC„

6218,AA180912„20,318,TGGTGATCTCTGCCACCGAC„

6219.AA180912„20,312,TCTCTGCCACCGACAGCTGC„

6220.AA 180912„20,306,CCACCGACAGCTGCTCGTGG„ 6221 ,AA180912„20,300,ACAGCTGCTCGTGGTATGCC„

6222,AA180912„20,294,GCTCGTGGTATGCCTTTTCT„

6223,AA180912„20,288,GGTATGCCTTTTCTGCAGAG„

6224,AA 180912„20,282,CCTTTTCTGCAGAGATGACT„

6225,AA180912„20,276,CTGCAGAGATGACTGGTGCA„ 6226,AA180912„20,270,AGATGACTGGTGCATAGGTG„

6227,AA180912„20,264,CTGGTGCATAGGTGGCCAGG„

6228,AA180912„20,258,CATAGGTGGCCAGGGGGAAG„

6229,AA180912„20,252,TGGCCAGGGGGAAGTGGATG„

6230,AA180912„20,246,GGGGGAAGTGGATGCGAGGG„ 6231,AA180912„20,240,AGTGGATGCGAGGGTAGGGC„

6232,AA180912„20,234,TGCGAGGGTAGGGCACCAGG„

6233,AA180912„20,228,GGTAGGGCACCAGGTTGGTC„

6234,AA180912„20,222,GCACCAGGTTGGTCTGGAAC„

6235,AA180912„20,216,GGTTGGTCTGGAACTCTGTC„ 6236.AA180912„20,210,TCTGGAACTCTGTCAGGTCC„

6237,AA180912„20,204,ACTCTGTCAGGTCCACATTG„

6238,AA180912„20,198,TCAGGTCCACATTGAGGGCC„

6239.AA180912„20, 192,CCACATTGAGGGCCCCGTCA„

6240,AA180912„20,186,TGAGGGCCCCGTCAAAGCGC„ 6241,AA180912„20,180,CCCCGTCAAAGCGCAGAGAA„ 6242,AA180912„20,174,CAAAGCGCAGAGAAGCTGTG„ 6243,AA180912„20,168,GCAGAGAAGCTGTGATGGAG„

6244,AA180912„20,162,AAGCTGTGATGGAGGAGACA„

6245,AA180912„20,156,TGATGGAGGAGACAATTTGG„ 6246,AA180912„20, 150,AGGAGACAATTTGGCTAATG„

6247,AA180912„20,144,CAATTTGGCTAATGAGGCGA„

6248,AA180912„20,138,GGCTAATGAGGCGATTGAGG„

6249.AA180912„20, 132,TGAGGCGATTGAGGTTGGTG„

6250.AA180912„20, 126,GATTGAGGTTGGTGTAGGTT„ 6251,AA180912„20,120,GGTTGGTGTAGGTTGGGCGC„

6252,AA180912„20,114,TGTAGGTTGGGCGCTCGATG„

6253,AA180912„20,108,TTGGGCGCTCGATGTCTAGG„

6254,AA180912„20,102,GCTCGATGTCTAGGTTGCGG„

6255,AA180912„20,96,TGTCTAGGTTGCGGCGGCAG„ 6256,AA180912„20,90,GGTTGCGGCGGCAGATGTCA„

6257,AA180912„20,84,GGCGGCAGATGTCATAGATT„

6258,AA180912„20,78,AGATGTCATAGATTGCTTCG„

6259,AA180912„20,72,CATAGATTGCTTCGTTGTCC„

6260,AA180912„20,66,TTGCTTCGTTGTCCACCATG„ 6261 ,AA 180912„20,60,CGTTGTCCACCATGAAGGCA„

6262,AA 180912„20,54,CCACCATGAAGGCACAGTCT„

6263,AA-180912„20,48,TGAAGGCACAGTCTGAGTGC„

6264,AA180912„20,42,CACAGTCTGAGTGCTCCAGG„

6265,AA180912„20,36,CTGAGTGCTCCAGGGTGGTG„ 6266,AA180912„20,30,GCTCCAGGGTGGTGTGGGTG„

6267,AA180912„20,24,GGGTGGTGTGGGTGGTCAGG„

6268,AA180912„20,18,TGTGGGTGGTCAGGATAGAG„

6269,AA180912„20,12,TGGTCAGGATAGAGTTGTAG„

6270,AA180912„20,6,GGATAGAGTTGTAGGGCTCG„ (GENBANK ACCESSION NO. AA436142)

TGCAGACAAAGTAAAATTTATTGAGACAGACAGAAATGCACCTACTCAGGACTACAGTTAAGCATTTACTATTAACCAAAGAGTTG

TGTTCACATTCCAGATAAGTCTACGTGGAAAAGCATTCAGAATTTACTAGGTTTTTGCTACATCACTATTTCATCTACAATAGGGACA

ACAAACTGACACTCAGGATTTGATGGGCTCTCATTACAATGCTATACATTTAACAGGAACAAACATCAGTGACTTTGAGAAAAAGTT

ATAAAAAGACCAAAACCACCCACTGTAGAATGGGCTCTTGGATGTTACTGTACAGCGTGGTCAAGGTAACAAGAAGAAAAAAATGT GAGTGGCATCCTGGGATGAGCCGGGGGACAGACCTGGACAGACACGTTGTCATTTGCTGCTGTGGGTAGGAAAATGGGCGTAAAGG

AGGAGAAACAGATA

(SEQ ID NO: 6271)

6272,AA436142„20,428,TATCTGTTTCTCCTCCTTTA„ 6273,AA436142„20,422,TTTCTCCTCCTTTACGCCCA„

6274,AA436142„20,416,CTCCTTTACGCCCATTTTCC„

6275,AA436142„20,410,TACGCCCATTTTCCTACCCA„

6276,AA436142„20,404,CATTTTCCTACCCACAGCAG„

6277,AA436142„20,398,CCTACCCACAGCAGCAAATG„ 6278,AA436142„20,392,CACAGCAGCAAATGACAACG„

6279,AA436142„20,386,AGCAAATGACAACGTGTCTG„

6280,AA436142„20,380,TGACAACGTGTCTGTCCAGG„

6281,AA436142„20,374,CGTGTCTGTCCAGGTCTGTC„

6282,AA436142„20,368,TGTCCAGGTCTGTCCCCCGG„ 6283,AA436142„20,362,GGTCTGTCCCCCGGCTCATC„

6284,AA436142„20,356,TCCCCCGGCTCATCCCAGGA„

6285,AA436142„20,350,GGCTCATCCCAGGATGCCAC„

6286,AA436142„20,344,TCCCAGGATGCCACTCACAT„

6287,AA436142„20,338,C 6288,AA436142„20,332,

6289,AA436142„20,326,ATTTTTTTCTTCTTGTTACC„

6290,AA436142„20,320,TTCTTCTTGTTACCTTGACC„

6291,AA436142„20,314,TTGTTACCTTGACCACGCTG„

6292,AA436142„20,308,CCTTGACCACGCTGTACAGT„ 6293,AA436142„20,302,CCACGCTGTACAGTAACATC„

6294,AA436142„20,296,TGTACAGTAACATCCAAGAG„

629₅,AA436142„20,290,GTAACATCCAAGAGCCCATT„

6296,AA436142„20,284,TCCAAGAGCCCATTCTACAG„

6297,AA436142„20,278,AGCCCATTCTACAGTGGGTG„ 6298,AA436142„20,272,TTCTACAGTGGGTGGTTTTG„

6299,AA436142„20,266,AGTGGGTGGTTTTGGTCTTT„

6300,AA436142„20,260,TGGTTTTGGTCTTTTTATAA„

6301,AA436142„20,2₅4,TGGTCTTTTTATAACTTTTT„

6302,AA436142,,20,248,TTTTATAACTTTTTCTCAAA„ 6303,AA436142„20,242,AACTTTTTCTCAAAGTCACT„

6304,AA436142„20,236,TTCTCAAAGTCACTGATGTT„

6305,AA436142„20,230,AAGTCACTGATGTTTGTTCC„

6306,AA436142„20,224,CTGATGTTTGTTCCTGTTAA„

6307,AA436142„20,218,TTTGTTCCTGTTAAATGTAT„ 6308,AA436142„20,212,CCTGTTAAATGTATAGCATT„ 6309,AA436142„20,206,AAATGTATAGCATTGTAATG„

6310,AA436142„20,200,ATAGCATTGTAATGAGAGCC„

6311 ,AA436142„20, 194,TTGTAATGAGAGCCCATCAA„

6312,AA436142„20,188,TGAGAGCCCATCAAATCCTG„ 6313,AA436142„20,182,CCCATCAAATCCTGAGTGTC„

6314,AA436142„20,176,AAATCCTGAGTGTCAGTTTG„

6315,AA436142„20,170,TGAGTGTCAGTTTGTTGTCC„

6316,AA436142„20,164,TCAGTTTGTTGTCCCTATTG„

6317,AA436142„20,158,TGTTGTCCCTATTGTAGATG„ 6318,AA436142„20,152,CCCTATTGTAGATGAAATAG„

6319,AA436142„20,146,TGTAGATGAAATAGTGATGT„

6320,AA436142„20,140,TGAAATAGTGATGTAGCAAA„

6321 ,AA436142„20, 134,AGTGATGTAGCAAAAACCTA„

6322,AA436142„20,128,GTAGCAAAAACCTAGTAAAT„ 6323,AA436142„20,122,AAAACCTAGTAAATTCTGAA„

6324.AA436142„20, 116,TAGTAAATTCTGAATGCTTT„

6325,AA436142„20,110,ATTCTGAATGCTTTTCCACG„

6326,AA436142„20,104,AATGCTTTTCCACGTAGACT„

6327,AA436142„20,98,TTTCCACGTAGACTTATCTG„ 6328,AA436142„20,92,CGTAGACTTATCTGGAATGT„

6329,AA436142„20,86,CTTATCTGGAATGTGAACAC„

6330,AA436142„20,80,TGGAATGTGAACACAACTCT„

6331 ,AA436142„20,74,GTGAACACAACTCTTTGGTT„

6332,AA436142„20,68,ACAACTCTTTGGTTAATAGT„ 6333,AA436142„20,62,CTTTGGTTAATAGTAAATGC„

6334,AA436142„20,56,TTAATAGTAAATGCTTAACT„

6335,AA436142„20,50,GTAAATGCTTAACTGTAGTC„

6336,AA436142„20,44,GCTTAACTGTAGTCCTGAGT„

6337,AA436142„20,38,CTGTAGTCCTGAGTAGGTGC„ 6338,AA436142„20,32,TCCTGAGTAGGTGCATTTCT„

6339,AA436142„20,26,GTAGGTGCATTTCTGTCTGT„

6340,AA436142„20,20,GCATTTCTGTCTGTCTCAAT„

6341,AA436142„20,14,CTGTCTGTCTCAATAAATTT„

6342,AA436142„20,8,GTCTCAATAAATTTTACTTT„ 6343,AA436142„20,2,ATAAATTTTACTTTGTCTGC„

(GENBANK ACCESSION NO. H05893)

TTTTTTTTTTNACCTTGGGGATAAAAGTCTTTATTGAACAACCTTATCTCACTCAGTAACAAAAGAGCAGGAGGCGACAATTCCCCC

AGAAGTCTGCAGCCGTGTCCACCCTTGGCAGCAGGATGCATGTCCTGCTGATAACATCAGCTGCAGTTCAGAGCCCCTGGTGGTCAC

TTAGAGATCATAATTGGGGTTCTTCCGAAGATTAACAAAACCTTCCAGAATGGGGGTAACAGGAAGAAACTCCTCAGTGGCCAATT CTGCCCGTTCCCCGTGGGCCAACAACACTGGGGTTGTATGCGTCTGGAACCCTGTGATAGTCTTCGGNTTGCCAGCCTGGGCCCACC

ACATCCACTGCCTGGGCCCACACGGACAGACACTGGGCAATGGGCCGCAGTTTCCTCATCAAACGTAAACCAGGCATTTCGGGGGT

(SEQ LD NO: 6344)

634₅,H05893„20,414,ACCCCCGAAATGCCTGGTTT„ 6346,H05893,,20,408,GAAATGCCTGGTTTACGTTT„

6347,H05893„20,402,CCTGGTTTACGTTTGATGAG„

6348,H05893„20,396,TTACGTTTGATGAGGAAACT„

6349,H05893„20,390,TTGATGAGGAAACTGCGGCC„

6350,H05893„20,384,AGGAAACTGCGGCCCATTGC„ 6351,H05893„20,378,CTGCGGCCCATTGCCCAGTG„

6352,H05893„20,372,CCCATTGCCCAGTGTCTGTC„

6353,H05893„20,366,GCCCAGTGTCTGTCCGTGTG„

6354,H05893„20,360,TGTCTGTCCGTGTGGGCCCA„

6355,H05893„20,354,TCCGTGTGGGCCCAGGCAGT„ 6356,H05893„20,348,TGGGCCCAGGCAGTGGATGT„

6357,H05893„20,342,CAGGCAGTGGATGTGGTGGG„

6358,H05893„20,336,GTGGATGTGGTGGGCCCAGG„

6359,H05893„20,330,GTGGTGGGCCCAGGCTGGCA„

6360,H05893„20,324,GGCCCAGGCTGGCAANCCGA„ 6361,H05893„20,318,GGCTGGCAANCCGAAGACTA„

6362,H0₅893„20,312,CAANCCGAAGACTATCACAG„

6363,H0₅893„20,306,GAA^'GACTATCACAGGGTTCC„

6364,H0₅893„20,300,TATCACAGGGTTCCAGACGC„

6365,H05893„20,294,AGGGTTCCAGACGCATACAA„ 6366,H05893„20,288,CCAGACGCATACAACCCCAG„

6367,H05893„20,282,GCATACAACCCCAGTGTTGT„

6368,H05893„20,276,AACCCCAGTGTTGTTGGCCC„

6369,H05893„20,270,AGTGTTGTTGGCCCACGGGG„

6370,H05893„20,264,GTTGGCCCACGGGGAACGGG„ 6371,H05893„20,258,CCACGGGGAACGGGCAGAAT„

6372,H05893„20,252,GGAACGGGCAGAATTGGCCA„

6373,H05893„20,246,GGCAGAATTGGCCACTGAGG„

6374,H05893„20,240,ATTGGCCACTGAGGAGTTTC„

6375,H0₅893„20,234,CACTGAGGAGTTTCTTCCTG„ 6376,H05893,,20,228,GGAGTTTCTTCCTGTTACCC„ 6377,H05893„20,222,TCTTCCTGTTACCCCCATTC„

6378,H05893„20,216,TGTTACCCCCATTCTGGAAG„

6379,H05893„20,210,CCCCATTCTGGAAGGTTTTG„

6380,H05893„20,204,TCTGGAAGGTTTTGTTAATC„ 6381,H05893„20,198,AGGTTTTGTTAATCTTCGGA„

6382,H05893„20, 1 2,TGTTAATCTTCGGAAGAACC„

6383,H05893„20,186,TCTTCGGAAGAACCCCAATT„

6384,H05893„20,180,GAAGAACCCCAATTATGATC„

6385,H05893„20,174,CCCCAATTATGATCTCTAAG„ 6386,H05893„20, 168,TTATGATCTCTAAGTGACCA„

6387,H05893„20,162,TCTCTAAGTGACCACCAGGG„

6388,H05893„20,156,AGTGACCACCAGGGGCTCTG„

6389,H05893„20,150,CACCAGGGGCTCTGAACTGC„

6390,H05893„20,144,GGGCTCTGAACTGCAGCTGA„ 6391,H05893„20,138,TGAACTGCAGCTGATGTTAT„

6392,H05893„20,132,GCAGCTGATGTTATCAGCAG„

6393,H05893„20,126,GATGTTATCAGCAGGACATG„

6394,H05893„20,120,ATCAGCAGGACATGCATCCT„

6395,H05893„20,114,AGGACATGCATCCTGCTGCC„ 6396,H05893„20,108,TGCATCCTGCTGCCAAGGGT„

6397,H05893„20,102,CTGCTGCCAAGGGTGGACAC„

6398,H05893„20,96,CCAAGGGTGGACACGGCTGC„

6399,H05893„20,90,GTGGACACGGCTGCAGACTT„

6400,H05893„20,84,ACGGCTGCAGACTTCTGGGG„ 6401,H05893„20,78,GCAGACTTCTGGGGGAATTG„

6402,H05893„20,72,TTCTGGGGGAATTGTCGCCT„

6403,H05893„20,66,GGGAATTGTCGCCTCCTGCT„

6404,H05893,,20,60,TGTCGCCTCCTGCTCTTTTG„

6405,H05893„20,54,CTCCTGCTCTTTTGTTACTG„ 6406,H05893„20,48,CTCTTTTGTTACTGAGTGAG„

6407,H05893„20,42,TGTTACTGAGTGAGATAAGG„

6408,H05893„20,36,TGAGTGAGATAAGGTTGTTC„

6409,H05893„20,30,AGATAAGGTTGTTCAATAAA„

6410,H05893„20,24,GGTTGTTCAATAAAGACTTT„ 6411,H05893„20,18,TCAATAAAGACTTTTATCCC„

6412,H05893„20,12,AAGACTTTTATCCCCAAGGT„

6413,H05893„20,6,TTTATCCCCAAGGTNAAAAA„

(GENBANK ACCESSION NO. H37989)

GCACGNGGAGGCCTAAGNAGAGCCCCATCACCTCAGGCTTCTCAGTTCCCTTAGCCGTCTTACTCAACTACCCCTTTCCTCTCCCTC AGAATTTGTGTTTGCTGCCTCTATCTTGTTTTTTGTTTTTTCTTCTGGGGGGGGTCTAGAACAGTGCCTGGCACATAGTAGGCGCTCA

ATAAATACTTGTTTGTTGAATGTCTCCTCTCTCTTTCCACTCTGGGAAACCTAGGTTTCTGCCATTCTGGGTGACCCTGTATTTCTTTC

TGGTGCCCATTCCATTTGTCCAGTTAATACTTCCTCTTAAAAATCTCCAAGAAGCTGGGTCTCCAGATCCCATTTAGAACCAACCAG

GTGCTGAAAACACATGTAGATAATGGCCATCATCCTAAGCCCAAAGTAGAAAATGGTAGAAGNGTAGTGGGTAGAAGNCACTATAT

AAGGAAG (SEQ ID NO: 6414)

6415,H37989„20,425,CTTCCTTATATAGTGNCTTC„

6416,H37989„20,419,TATATAGTGNCTTCTACCCA„

6417,H37989„20,413,GTGNCTTCTACCCACTACNC„ 6418,H37989„20,407,TCTACCCACTACNCTTCTAC„

6419,H37989„20,401 ,CACTACNCTTCTACCATTTT„

6420,H37989„20,395,NCTTCTACCATTTTCTACTT„

6421,H37989„20,389,ACCATTTTCTACTTTGGGCT„

6422,H37989„20,383,TTCTACTTTGGGCTTAGGAT„ 6423,H37989„20,377,TTTGGGCTTAGGATGATGGC„

6424,H37989„20,371 ,CTTAGGATGATGGCCATTAT„

6425,H37989„20,365,ATGATGGCCATTATCTACAT„

6426,H37989„20,359,GCCATTATCTACATGTGTTT„

6427,H37989„20,353,ATCTACATGTGTTTTCAGCA„ 6428,H37989„20,347,ATGTGTTTTCAGCACCTGGT„

6429,H37989„20,341,TTTCAGCACCTGGTTGGTTC„

6430,H37989„20,335,CACCTGGTTGGTTCTAAATG„

6431 ,H37989„20,329,GTTGGTTCTAAATGGGATCT„

6432,H37989„20,323,TCTAAATGGGATCTGGAGAC„ 6433,H37989„20,317,TGGGATCTGGAGACCCAGCT„

6434,H37989„20,311 ,CTGGAGACCCAGCTTCTTGG„

6435,H37989„20,305,ACCCAGCTTCTTGGAGATTT„

6436,H37989„20,299,CTTCTTGGAGATTTTTAAGA„

6437,H37989„20,293,GGAGATTTTTAAGAGGAAGT„ 6438,H37989„20,287,TTTTAAGAGGAAGTATTAAC„

6439,H37989„20,281,GAGGAAGTATTAACTGGACA„

6440,H37989„20,275,GTATTAACTGGACAAATGGA„

6441,H37989„20,269,ACTGGACAAATGGAATGGGC„

6442,H37989„20,263,CAAATGGAATGGGCACCAGA„ 6443,H37989„20,257,GAATGGGCACCAGAAAGAAA„ 6444,H37989„20,251,GCACCAGAAAGAAATACAGG„

6445,H37989„20,245,GAAAGAAATACAGGGTCACC„

6446,H37989„20,239,AATACAGGGTCACCCAGAAT„

6447,H37989„20,233,GGGTCACCCAGAATGGCAGA„ 6448,H37989„20,227,CCCAGAATGGCAGAAACCTA„

6449,H37989„20,221 ,ATGGCAGAAACCTAGGTTTC„

6450,H37989„20,215,GAAACCTAGGTTTCCCAGAG„

6451,H37989„20,209,TAGGTTTCCCAGAGTGGAAA„

6452,H37989„20,203,TCCCAGAGTGGAAAGAGAGA„ 6453,H37989„20,197,AGTGGAAAGAGAGAGGAGAC„

6454,H37989„20, 191 ,AAGAGAGAGGAGACATTCAA„

6455,H37989„20, 185,GAGGAGACATTCAACAAACA„

6456,H37989„20,179,ACATTCAACAAACAAGTATT„

6457,H37989„20,173,AACAAACAAGTATTTATTGA„ 6458,H37989„20,167,CAAGTATTTATTGAGCGCCT„

6459,H37989„20,161,TTTATTGAGCGCCTACTATG„

6460,H37989„20, 155,GAGCGCCTACTATGTGCCAG„

6461 ,H37989„20, 149,CTACTATGTGCCAGGCACTG„

6462,H37989„20,143,TGTGCCAGGCACTGTTCTAG„ 6463,H37989„20,137,AGGCACTGTTCTAGACCCCC„

6464,H37989„20, 131 ,TGTTCTAGACCCCCCCCAGA„

6465,H37989„20,125,AGACCCCCCCCAGAAGAAAA„

6466,H37989„20, 119.CCCCCAGAAGAAAAAACAAA,,

6467,H37989„20,113,GAAGAAAAAACAAAAAACAA„ 6468,H37989„20,107,AAAACAAAAAACAAGATAGA„

6469,H37989„20, 101 ,AAAAACAAGATAGAGGCAGC„

6470,H37989„20,95,AAGATAGAGGCAGCAAACAC„

6471 ,H37989„20,89,GAGGCAGCAAACACAAATTC„

6472,H37989„20,83,GCAAACACAAATTCTGAGGG„ 6473,H37989„20,77,ACAAATTCTGAGGGAGAGGA„

6474,H37989„20,71 ,TCTGAGGGAGAGGAAAGGGG„

6475,H37989„20,65,GGAGAGGAAAGGGGTAGTTG„

6476,H37989„20,59,GAAAGGGGTAGTTGAGTAAG„

6477,H37989„20,53,GGTAGTTGAGTAAGACGGCT„ 6478,H37989„20,47,TGAGTAAGACGGCTAAGGGA„

6479,H37989„20,41,AGACGGCTAAGGGAACTGAG„

6480,H37989„20,35,CTAAGGGAACTGAGAAGCCT„

6481 ,H37989„20,29,GAACTGAGAAGCCTGAGGTG„

6482,H37989„20,23,AGAAGCCTGAGGTGATGGGG„ 6483,H37989„20,17,CTGAGGTGATGGGGCTCTNC„

6484,H37989„20,11,TGATGGGGCTCTNCTTAGGC„

6485,H37989„20,5,GGCTCTNCTTAGGCCTCCNC„

(GENBANK ACCESSION NO. AA486238)

AAAGGGGACACCTAGTTTGGTTGTCATTTGGCAAAGGAGATGACTTAAAATCCGCTTAATCTCTTCCAGTGTCCGTGTTAATGTATTT GGCTATTAGATCACTAGCACTGCTTTACCGCTCCTCATCGCCAACACCCCCATGCTCTGTGGCCTTCTTACACTTCTCAGAGGGCAGA

GTGGCAGCCGGGCACCCTACAGAAACTCAGAGGGCAGAGTGGCAGCCAGGCCCACATGTCTCTCAAGTACCTGTCCCCTCGCTCTG

GTGATTATTTCTTGCAGAATCACCACACGAGACCATCCCGGCAGTCATGGTTTTGCTTTAGTTTTCCAAGTCCGTTTCAGTCCCTTCC

TTGGTCTGAAGAAATTCTGCAGTGGCGAGCAGTTTCCCACTTGCCAAGATCCCTTTT

(SEQ LD NO: 6486)

6487,AA486238„20,388,AAAAGGGATCTTGGCAAGTG„

6488,AA486238„20,382,GATCTTGGCAAGTGGGAAAC„

6489,AA486238„20,376,GGCAAGTGGGAAACTGCTCG„

6490,AA486238„20,370,TGGGAAACTGCTCGCCACTG„ 6491,AA486238„20,364,ACTGCTCGCCACTGCAGAAT„

6492,AA486238„20,358,CGCCACTGCAGAATTTCTTC„

6493,AA486238„20,352,TGCAGAATTTCTTCAGACCA„

6494,AA486238„20,346,ATTTCTTCAGACCAAGGAAG„

6495,AA486238„20,340,TCAGACCAAGGAAGGGACTG„ 6496,AA486238„20,334,CAAGGAAGGGACTGAAACGG„

6497,AA486238„20,328,AGGGACTGAAACGGACTTGG„

6498,AA486238„20,322,TGAAACGGACTTGGAAAACT„

6499,AA486238„20,316,GGACTTGGAAAACTAAAGCA„

6500,AA486238„20,310,GGAAAACTAAAGCAAAACCA„ 6501,AA486238„20,304,CTAAAGCAAAACCATGACTG„

6502,AA486238„20,298,CAAAACCATGACTGCCGGGA„

6503,AA486238„20,292,CATGACTGCCGGGATGGTCT„

6504,AA486238„20,286,TGCCGGGATGGTCTCGTGTG„

6505,AA486238„20,280,GATGGTCTCGTGTGGTGATT„ 6506,AA486238„20,274,CTCGTGTGGTGATTCTGCAA„

6507,AA486238„20,268,TGGTGATTCTGCAAGAAATA„

6508,AA486238„20,262,TTCTGCAAGAAATAATCACC„

6509,AA486238„20,256,AAGAAATAATCACCAGAGCG„

6510,AA486238„20,250,TAATCACCAGAGCGAGGGGA„ 6511 ,AA486238„20,244,CCAGAGCGAGGGGACAGGTA„ 6512,AA486238„20,238,CGAGGGGACAGGTACTTGAG„

6₅13,AA486238„20,232,GACAGGTACTTGAGAGACAT„

6514,AA486238„20,226,TACTTGAGAGACATGTGGGC„

6515,AA486238„20,220,AGAGACATGTGGGCCTGGCT„ 6516,AA486238„20,214,ATGTGGGCCTGGCTGCCACT„

6517,AA486238„20,208,GCCTGGCTGCCACTCTGCCC„

6518,AA486238„20,202,CTGCCACTCTGCCCTCTGAG„

6519,AA486238„20,196,CTCTGCCCTCTGAGTTTCTG„

6520,AA486238„20, 190,CCTCTGAGTTTCTGTAGGGT„ 6521 ,AA486238„20, 184,AGTTTCTGTAGGGTGCCCGG„

6522,AA486238„20,178,TGTAGGGTGCCCGGCTGCCA„

6523,AA486238„20,172,GTGCCCGGCTGCCACTCTGC„

6524,AA486238„20, 166,GGCTGCCACTCTGCCCTCTG„

6525,AA486238„20, 160,CACTCTGCCCTCTGAGAAGT„ 6526,AA486238„20,154,GCCCTCTGAGAAGTGTAAGA„

6₅27,AA486238„20,148,TGAGAAGTGTAAGAAGGCCA„

6528,AA486238„20,142,GTGTAAGAAGGCCACAGAGC„

6529,AA486238„20,136,GAAGGCCACAGAGCATGGGG„

6530,AA486238„20,130,CACAGAGCATGGGGGTGTTG„ 6531,AA486238„20,124,GCATGGGGGTGTTGGCGATG„

6532,AA486238„20,118,GGGTGTTGGCGATGAGGAGC„

6533,AA486238„20, 112,TGGCGATGAGGAGCGGTAAA„

6534,AA486238„20,106,TGAGGAGCGGTAAAGCAGTG„

6535,AA486238„20,100,GCGGTAAAGCAGTGCTAGTG„ 6536,AA486238„20,94,AAGCAGTGCTAGTGATCTAA„

6537,AA486238„20,88,TGCTAGTGATCTAATAGCCA„

6538,AA486238„20,82,TGATCTAATAGCCAAATACA„

6539,AA486238„20,76,AATAGCCAAATACATTAACA„

6540,AA486238„20,70,CAAATACATTAACACGGACA„ 6541,AA486238„20,64,CATTAACACGGACACTGGAA„

6542,AA486238„20,58,CACGGACACTGGAAGAGATT„

6543,AA486238„20,52,CACTGGAAGAGATTAAGCGG„

6544,AA486238„20,46,AAGAGATTAAGCGGATTTTA„

6545,AA486238„20,40,TTAAGCGGATTTTAAGTCAT„ 6546,AA486238,,20,34,GGATTTTAAGTCATCTCCTT„

6547,AA486238„20,28,TAAGTCATCTCCTTTGCCAA„

6₅48,AA486238„20,22,ATCTCCTTTGCCAAATGACA„

6549,AA486238„20,16,TTTGCCAAATGACAACCAAA„

6550,AA486238„20,10,AAATGACAACCAAACTAGGT„ 6551,AA486238„20,4,CAACCAAACTAGGTGTCCCC„

(GENBANK ACCESSION NO. AA504461)

CCTGCCCCTCTCTGTCCCCGGCATTCATTGACACGGGCTTTCCCTGGCCTGTGATCCCATCCCAACACACACGACAGAAAACAGTGC

AAAATAATAACACAAATGCCAAATGTACACAGTGTACAACTCTGAACTGAGAAAGTGCAAGGAGACCACGGGAATGGAAGTGGGT

AGGGGTCGGGAGGATGGGCACCAGGCTGGTGTCCTGACAGCCACACCTGGGTGCAGGCCACGTGTCCTCACGGCCAAGGTAACCG GGTGTCTCAGGCACTTAATAAATATTAAGGGTGACCGGTGACTCAGGCTCTGCCTCTGGGAAGTGGCATCATTTGGTGAATGAGTTT

GGTCTCGGTGCCACC

(SEQ ID NO: 6552)

6553,AA504461„20,340,GGTGGCACCGAGACCAAACT„ 6554,AA504461„20,334,ACCGAGACCAAACTCATTCA„

6555,AA504461„20,328,ACCAAACTCATTCACCAAAT„

6556,AA504461„20,322,CTCATTCACCAAATGATGCC„

6557,AA504461„20,316,CACCAAATGATGCCACTTCC„

6558,AA504461„20,310,ATGATGCCACTTCCCAGAGG„ 6559,AA504461„20,304,CCACTTCCCAGAGGCAGAGC„

6560.AA504461 „20,298,CCCAGAGGCAGAGCCTGAGT„

6561.AA504461 „20,292,GGCAGAGCCTGAGTCACCGG„

6562,AA504461„20,286,GCCTGAGTCACCGGTCACCC„

6563,AA₅04461„20,280,GTCACCGGTCACCCTTAATA„ 6₅64,AA₅04461 „20,274,GGTCACCCTTAATATTTATT„

6₅65,AA504461„20,268,CCTTAATATTTATTAAGTGC„

6566,AA504461„20,262,TATTTATTAAGTGCCTGAGA„

6567,AA504461„20,256,TTAAGTGCCTGAGACACCCG„

6568,AA504461„20,250,GCCTGAGACACCCGGTTACC„ 6569,AA₅04461 „20,244,GACACCCGGTTACCTTGGCC„

6₅70,AA504461 ,,20,238,CGGTTACCTTGGCCGTGAGG„

6571 ,AA504461 „20,232,CCTTGGCCGTGAGGACACGT„

6572,AA504461 „20,226,CCGTGAGGACACGTGGCCTG„

6573,AA504461„20,220,GGACACGTGGCCTGCACCCA„ 6574,AA504461„20,214,GTGGCCTGCACCCAGGTGTG„

6575,AA504461„20,208,TGCACCCAGGTGTGGCTGTC„

6576,AA₅04461„20,202,CAGGTGTGGCTGTCAGGACA„

6577,AA504461„20, 196,TGGCTGTCAGGACACCAGCC„

6578,AA504461 „20, 190,TCAGGACACCAGCCTGGTGC„ 6579,AA504461„20,184,CACCAGCCTGGTGCCCATCC„ 6580.AA504461 „20, 178,CCTGGTGCCCATCCTCCCGA„

6581,AA504461„20,172,GCCCATCCTCCCGACCCCTA„

6582,AA504461 „20, 166,CCTCCCGACCCCTACCCACT„

6583,AA504461„20,160,GACCCCTACCCACTTCCATT„ 6584,AA504461,,20,154,TACCCACTTCCATTCCCGTG„

6585,AA504461„20,148,CTTCCATTCCCGTGGTCTCC„

6586,AA504461„20,142,TTCCCGTGGTCTCCTTGCAC„

6587,AA504461„20,136,TGGTCTCCTTGCACTTTCTC„

6588,AA504461„20,130,CCTTGCACTTTCTCAGTTCA„ 6589,AA504461„20,124,ACTTTCTCAGTTCAGAGTTG„

6590,AA504461„20,118₎TCAGTTCAGAGTTGTACACT„

6591,AA504461„20,112,CAGAGTTGTACACTGTGTAC„

6592,AA₅04461„20,106,TGTACACTGTGTACATTTGG„

6593,AA504461„20,100,CTGTGTACATTTGGCATTTG„ 6594,AA504461„20,94,ACATTTGGCATTTGTGTTAT„

6595,AA504461„20,88,GGCATTTGTGTTATTATTTT„

6596,AA504461„20,82,TGTGTTATTATTTTGCACTG„

6597,AA504461„20,76,ATTATTTTGCACTGTTTTCT„

6598,AA504461„20,70,TTGCACTGTTTTCTGTCGTG„ 6599,AA504461 „20,64,TGTTTTCTGTCGTGTGTGTT„

6600,AA504461„20,58,CTGTCGTGTGTGTTGGGATG„

6601 ,AA504461 ,,20,52/TGTGTGTTGGGATGGGATCA,,

6602.AA504461 „20,46,TTGGGATGGGATCACAGGCC„

6603,AA504461 „20,40,TGGGATCACAGGCCAGGGAA„ 6604.AA504461 „20,34,CACAGGCCAGGGAAAGCCCG„

6605,AA504461 „20,28,CCAGGGAAAGCCCGTGTCAA„

6606.AA504461 „20,22,AAAGCCCGTGTCAATGAATG„

6607,AA504461 „20, 16,CGTGTCAATGAATGCCGGGG„

6608,AA504461„20,10,AATGAATGCCGGGGACAGAG„ 6609,AA₅04461„20,4,TGCCGGGGACAGAGAGGGGC„

(GENBANK ACCESSION NO. AA448400)

TITAAGGi GGAATTGCTrTTATTGGGGGCGGATACCGCAAGCCCCGCCCACGGTCAGGTTAGTGTTCTGCCCTTGCAGAGGCGCCA

GAGCCTGACACCTCCACCTGCCACCCGCCCGGGGTGTAGTGGAACATGCAAAGCTCCGACGGTGGAGGCAGGGGTGGTCGCTGCTG

AGACCAGGGCTGGGTGCAACAGGAGGGTCAGCACAGAGCCTGGCTGGTGTCCCTGGGCCCAAAGGGGCTGGGGCTCCATGGGAGA GAGACGGGCAGGCGGCACCCCAGTGTGGGGCTCCACAAGCTGGAGGGGCCCCTGGACCTACCAGGAGGACAGGTCTGCAGTTCCC

AGCCATGCCGGCTGGAACGTCCGCCTCCCCACTGGGTCTGGGTCCTCGGGGCCTGGGGTTAGAGGCCGACATGGAAGGACTTACTA

GGGGAACAGAGGCTGGAGGCTGACGCC

(SEQ ID NO: 6610) 6611,AA448400„20,437,GGCGTCAGCCTCCAGCCTCT„

6612,AA448400„20,431,AGCCTCCAGCCTCTGTTCCC„

6613,AA448400„20,42₅₎CAGCCTCTGTTCCCCTAGTA„

6614,AA448400„20,419,CTGTTCCCCTAGTAAGTCCT„

6615,AA448400„20,413,CCCTAGTAAGTCCTTCCATG„ 6616,AA448400„20,407,TAAGTCCTTCCATGTCGGCC„

6617,AA448400„20,401 ,CTTCCATGTCGGCCTCTAAC„

6618,AA448400„20,395,TGTCGGCCTCTAACCCCAGG„

₆619,AA448400„20,389,CCTCTAACCCCAGGCCCCGA„

6620,AA448400„20,383₎ACCCCAGGCCCCGAGGACCC„ 6621,AA448400„20,377,GGCCCCGAGGACCCAGACCC„

6622,AA448400„20,371 ,GAGGACCCAGACCCAGTGGG„

6623,AA448400„20,365,CCAGACCCAGTGGGGAGGCG„

6624,AA448400„20,3₅9,CCAGTGGGGAGGCGGACGTT„

6625,AA448400„20,353,GGGAGGCGGACGTTCCAGCC„ 6626,AA448400„20,347,CGGACGTTCCAGCCGGCATG„

6627,AA448400„20,341,TTCCAGCCGGCATGGCTGGG„

6628,AA448400„20,335,CCGGCATGGCTGGGAACTGC„

6629,AA448400„20,329,TGGCTGGGAACTGCAGACCT„

6630,AA448400„20,323,GGAACTGCAGACCTGTCCTC„ 6631,AA448400„20,317,GCAGACCTGTCCTCCTGGTA„

6632,AA448400„20,311 ,CTGTCCTCCTGGTAGGTCCA„

6633,AA448400„20,305,TCCTGGTAGGTCCAGGGGCC„

6634,AA448400„20,299,TAGGTCCAGGGGCCCCTCCA„

6635,AA448400„20,293,CAGGGGCCCCTCCAGCTTGT„ 6636,AA448400„20,287,CCCCTCCAGCTTGTGGAGCC„

6637,AA448400„20,281 ,CAGCTTGTGGAGCCCCACAC„

6638,AA448400„20,275,GTGGAGCCCCACACTGGGGT„

6639,AA448400„20,269,CCCCACACTGGGGTGCCGCC„

6640,AA448400„20,263,ACTGGGGTGCCGCCTGCCCG„ 6641,AA448400„20,257,GTGCCGCCTGCCCGTCTCTC„

6642,AA448400„20,251 ,CCTGCCCGTCTCTCTCCCAT„

6643,AA448400„20,245,CGTCTCTCTCCCATGGAGCC„

6644,AA448400„20,239,TCTCCCATGGAGCCCCAGCC„

6645,AA448400„20,233,ATGGAGCCCCAGCCCCTTTG„ 6646,AA448400„20,227,CCCCAGCCCCTTTGGGCCCA„ 6647,AA448400„20,221 ,CCCCTTTGGGCCCAGGGACA„

6648,AA448400„20,215,TGGGCCCAGGGACACCAGCC„

6649,AA448400„20,209,CAGGGACACCAGCCAGGCTC„

6650,AA448400„20,203,CACCAGCCAGGCTCTGTGCT„ 66₅1,AA448400„20,197,CCAGGCTCTGTGCTGACCCT„

6652,AA448400„20, 191 ,TCTGTGCTGACCCTCCTGTT„

6653,AA448400„20,185,CTGACCCTCCTGTTGCACCC„

6654,AA448400„20, 179,CTCCTGTTGCACCCAGCCCT„

6655,AA448400„20,173,TTGCACCCAGCCCTGGTCTC„ 6656,AA448400„20, 167,CCAGCCCTGGTCTCAGCAGC„

6657,AA448400„20, 161 ,CTGGTCTCAGCAGCGACCAC„

6658,AA448400„20, 155,TCAGCAGCGACCACCCCTGC„

6659,AA448400„20,149,GCGACCACCCCTGCCTCCAC„

6660,AA448400„20,143,ACCCCTGCCTCCACCGTCGG„ 6661 ,AA448400„20, 137,GCCTCCACCGTCGGAGCTTT„

6662,AA448400„20,131,ACCGTCGGAGCTTTGCATGT„

6663,AA448400„20,125,GGAGCTTTGCATGTTCCACT„

6664,AA448400„20, 11 ,TTGCATGTTCCACTACACCC„

6665,AA448400„20, 113,GTTCCACTACACCCCGGGCG„ 6666,AA448400„20, 107,CTACACCCCGGGCGGGTGGC„

6667,AA448400„20,101,CCCGGGCGGGTGGCAGGTGG„

6668,AA448400„20,95,CGGGTGGCAGGTGGAGGTGT„

6669,AA44S400„20,89,GCAGGTGGAGGTGTCAGGCT„

6670,AA448400„20,83,GGAGGTGTCAGGCTCTGGCG„ 6671,AA448400„20,77,GTCAGGCTCTGGCGCCTCTG„

6672,AA448400„20,71 ,CTCTGGCGCCTCTGCAAGGG„

6673,AA448400„20,65,CGCCTCTGCAAGGGCAGAAC„

6674,AA448400„20,59,TGCAAGGGCAGAACACTAAC„

6675,AA448400„20,53,GGCAGAACACTAACCTGACC„ 6676,AA448400„20,47,ACACTAACCTGACCGTGGGC„

6677,AA448400„20,41 ,ACCTGACCGTGGGCGGGGCT„

6678,AA448400„20,35,CCGTGGGCGGGGCTTGCGGT„

6679,AA448400„20,29,GCGGGGCTTGCGGTATCCGC„

6680,AA448400„20,23,CTTGCGGTATCCGCCCCCAA„ 6681 ,AA448400„20, 17.GTATCCGCCCCCAATAAAAG,,

6682,AA448400„20, 11 ,GCCCCCAATAAAAGCAATTC„

6683,AA448400„20,5,AATAAAAGCAATTCCAACCT„

(GENBANK ACCESSION NO. AA480815)

CGGCTCACCATGTGTCACTCTCGCAGCTGCCACCCGACCATGACCATCCTGCAGGCCCCGACCCCGGCCCCCTCCACCATCCCGGGA CCCCGCGTGCTCCGGTCGCTGAGATCTTCACCTTCGACCCTCTCCCGGAGCCCGCAGCGCCCCTGCGGGCGCCCCAGCGTCNTCGCG

GGCACCGAAAGCGCAGCGCAGGGTTCTCTACCCTCGAGTGGTCCGGCGCCAGTGCCTAGTCGAGGAACCGAACCCAGCCAAAAGG

CTTCTCTTTCTGCTGCTCACCATCGTCTTCTGCCAGATCCTGATGGCTGAAGAGGGTGTGCCGGC

(SEQ LD NO: 6684) 6685,AA480815„20,305,GCCGGCACACCCTCTTCAGC,,

6686,AA480815„20,299,ACACCCTCTTCAGCCATCAG„

6687,AA480815„20,293,TCTTCAGCCATCAGGATCTG„

6688,AA480815„20,287,GCCATCAGGATCTGGCAGAA„

6689.AA480815„20,281 ,AGGATCTGGCAGAAGACGAT„ 6690,AA480815„20,275,TGGCAGAAGACGATGGTGAG„

6691,AA480815„20,269,AAGACGATGGTGAGCAGCAG„

6692.AA480815„20,263,ATGGTGAGCAGCAGAAAGAG„

6693,AA480815„20,257,AGCAGCAGAAAGAGAAGCCT„

6694.AA480815„20,251 ,AGAAAGAGAAGCCTTTTGGC„ 6695.AA480815„20,245,AGAAGCCTTTTGGCTGGGTT„

6696,AA480815„20,239,CTTTTGGCTGGGTTCGGTTC„

6697,AA480815„20,233,GCTGGGTTCGGTTCCTCGAC„

6698.AA480815„20,227,TTCGGTTCCTCGACTAGGCA„

6699,AA480S 15„20,221 ,TCCTCGACTAGGCACTGGCG„ 6700,AA480815„20,215,ACTAGGCACTGGCGCCGGAC„

6701 ,AA480815„20,209,CACTGGCGCCGGACCACTCG„

6702,AA480815„20,203,CGCCGGACCACTCGAGGGTA„

6703,AA480815„20, 197,ACCACTCGAGGGTAGAGAAC„

6704.AA480815„20, 191 ,CGAGGGTAGAGAACCCTGCG„ 6705.AA480815„20, 185,TAGAGAACCCTGCGCTGCGC„

6706.AA480815„20, 179,ACCCTGCGCTGCGCTTTCGG„

6707,AA4S0815„20,173,CGCTGCGCTTTCGGTGCCCG„

6708.AA480815„20, 167,GCTTTCGGTGCCCGCGANGA„

6709,AA480815„20, 161 ,GGTGCCCGCGANGACGCTGG„ 6710,AA480815„20,155,CGCGANGACGCTGGGGCGCC„

6711,AA480815„20, 149,GACGCTGGGGCGCCCGCAGG„

6712,AA480815„20,143,GGGGCGCCCGCAGGGGCGCT„

6713,AA480815„20,137,CCCGCAGGGGCGCTGCGGGC„

6714,AA480815„20,131,GGGGCGCTGCGGGCTCCGGG„ 6715,AA480815„20,125,CTGCGGGCTCCGGGAGAGGG„ 6716,AA480815„20, 119,GCTCCGGGAGAGGGTCGAAG„

6717.AA480815„20, 113,GGAGAGGGTCGAAGGTGAAG„

6718,AA480815„20,107,GGTCGAAGGTGAAGATCTCA„

6719,AA480815„20, 101 ,AGGTGAAGATCTCAGCGACC„ 6720,AA48081₅„20,95,AGATCTCAGCGACCGGAGCA„

6721 ,AA480815„20,89,CAGCGACCGGAGCACGCGGG„

6722,AA480815„20,83,CCGGAGCACGCGGGGTCCCG„

6723,AA480815„20,77,CACGCGGGGTCCCGGGATGG„

6724,AA480815„20,71 ,GGGTCCCGGGATGGTGGAGG„ 6725,AA480815„20,65,CGGGATGGTGGAGGGGGCCG„

6726.AA480815„20,59,GGTGGAGGGGGCCGGGGTCG„

6727.AA480815„20,53,GGGGGCCGGGGTCGGGGCCT„

6728,AA480815„20,47,CGGGGTCGGGGCCTGCAGGA„

6729,AA480815„20,41 ,CGGGGCCTGCAGGATGGTCA„ 6730,AA4S0815„20,35,CTGCAGGATGGTCATGGTCG„

6731 ,AA480815„20,29,GATGGTCATGGTCGGGTGGC„

6732,AA480815„20,23,CATGGTCGGGTGGCAGCTGC„

6733,AA480815„20,17,CGGGTGGCAGCTGCGAGAGT„

6734,AA480815„20, 11 ,GCAGCTGCGAGAGTGACACA„ 6735,AA480815„20,5,GCGAGAGTGACACATGGTGA„

(GENBANK ACCESSION NO. AA102454)

TGTGATTGCATGGGGTAACCNTTTATTTTTATTTAACAGTACATTTGGAAGAAGATAAGGCAACAAGGCAAAATTTCTGTAATGTTG

CTAGCATTTTCCCAAGGTAAAGCCAGGAAACAAACTTGTGTCCTTTCTATAAGAACTTCTAAGTGATGTCCCCTCTAACTCCATGGA

CAGACACTAGTGGTGGTGAAGTTCATAAAAGTTTTTGAGGTGGCAAACAGCTTATTTTGTCCTTTATCATAATTGGTTTACAAATTGG ATGCCTGGTTTTGGCATACTGGTTCAGTTGATCAAGCGCAGGATCCCTTT GGTCTTTGTAAGACCANGATGGTATAAGGCCGAATA

GGGGTCAAGAACTTGATTGTAAGGAGAACGATTTACTATTTACCCAATCAATATTCTACAAAACCTGTCTCTTGGTTNAACCCAAGC

GACAGAGGTGAGTCTTCTCTCCTGGACTCTCCAGATGCCTTGACAAGANTACTTCATGATATACCATGTTTCCCAGTTGGGCTCATG

GGAAATGGGTAATCTTGGGACTGGTTGTTTGGGTAGAANAACAGCTGGCATTTTTAACCTGGAAG

(SEQ ID NO: 6736)

6737,AA 102454„20,569,CTTCCAGGTTAAAAATGCCA„

6738,AA102454„20,563,GGTTAAAAATGCCAGCTGTT„

6739,AA102454„20,557,AAATGCCAGCTGTTNTTCTA„

6740,AA102454„20,551,CAGCTGTTNTTCTACCCAAA„ 6741,AA102454„20,545,TTNTTCTACCCAAACAACCA„

6742,AA102454,,20,539,TACCCAAACAACCAGTCCCA„

6743,AA102454„20,₅33,AACAACCAGTCCCAAGATTA„

6744,AA1024₅4„20,527,CAGTCCCAAGATTACCCATT„

6745,AA102454„20,521,CAAGATTACCCATTTCCCAT„ 6746,AA102454„20,515,TACCCATTTCCCATGAGCCC„

6747,AA102454„20,509,TTTCCCATGAGCCCAACTGG„

6748,AA102454„20,503,ATGAGCCCAACTGGGAAACA„

6749,AA102454„20,497,CCAACTGGGAAACATGGTAT„

6750,AA102454„20,491,GGGAAACATGGTATATCATG„ 6751 ,AA102454„20,485,CATGGTATATCATGAAGTAN„

6752,AA102454,,20,479,ATATCATGAAGTANTCTTGT„

6753,AA102454,,20,473,TGAAGTANTCTTGTCAAGGC„

6754,AA102454„20,467,ANTCTTGTCAAGGCATCTGG„

6755,AA102454„20,461,GTCAAGGCATCTGGAGAGTC„ 6756,AA102454„20,455,GCATCTGGAGAGTCCAGGAG„

6757,AA102454„20,449,GGAGAGTCCAGGAGAGAAGA„

6758,AA102454„20,443,TCCAGGAGAGAAGACTCACC„

6759,AA102454„20,437,AGAGAAGACTCACCTCTGTC„

6760,AA102454„20,431,GACTCACCTCTGTCGCTTGG„ 6761 ,AA102454„20,425,CCTCTGTCGCTTGGGTTNAA„

6762,AA102454„20,419,TCGCTTGGGTTNAACCAAGA„

6763,AA 102454„20,413,GGGTTNAACCAAGAGACAGG„

6764,AA102454„20,407,AACCAAGAGACAGGTTTTGT„

6765,AA102454„20,401,GAGACAGGTTTTGTAGAATA„ 6766,AA102454„20,395,GGTTTTGTAGAATATTGATT„

6767,AA102454„20,389,GTAGAATATTGATTGGGTAA„

6768,AA102454„20,383,TATTGATTGGGTAAATAGTA„

6769,AA102454„20,377,TTGGGTAAATAGTAAATCGT„

6770,AA102454„20,371,AAATAGTAAATCGTTCTCCT„ 6771 ,AA 102454„20,365,TAAATCGTTCTCCTTACAAT„

6772,AA102454„20,359,GTTCTCCTTACAATCAAGTT„

6773,AA102454„20,353,CTTACAATCAAGTTCTTGAC„

6774,AA102454„20,347,ATCAAGTTCTTGACCCCTAT„

6775,AA102454„20,341,TTCTTGACCCCTATTCGGCC„ 6776,AA102454„20,335,ACCCCTATTCGGCCTTATAC„

6777,AA102454„20,329,ATTCGGCCTTATACCATCNT„

6778,AA102454„20,323,CCTTATACCATCNTGGTCTT„

6779,AA102454„20,317,ACCATCNTGGTCTTACAAAG,,

6780,AA102454„20,311,NTGGTCTTACAAAGACCAAA„ 6781 ,AA 102454„20,305,TTACAAAGACCAAAAGGGAT„ 6782,AA102454„20,299,AGACCAAAAGGGATCCTGCG„ 6783,AA102454„20,293,AAAGGGATCCTGCGCTTGAT„ 6784,AA102454„20,287,ATCCTGCGCTTGATCAACTG„ 6785,AA102454„20,281,CGCTTGATCAACTGAACCAG„ 6786,AA102454„20,275,ATCAACTGAACCAGTATGCC„

6787,AA102454„20,269,TGAACCAGTATGCCAAAACC„ 6788,AA102454„20,263,AGTATGCCAAAACCAGGCAT„ 6789,AA102454„20,257,CCAAAACCAGGCATCCAATT„ 6790,AA102454„20,251,CCAGGCATCCAATTTGTAAA„ 6791,AA102454„20,245,ATCCAATTTGTAAACCAATT„

6792,AA1024₅4„20,239,TTTGTAAACCAATTATGATA„ 6793,AA102454„20,233,AACCAATTATGATAAAGGAC„ 6794,AA102454„20,227,TTATGATAAAGGACAAAATA„ 6795,AA1024S4„20,221,TAAAGGACAAAATAAGCTGT„ 6796,AA102454„20,215,ACAAAATAAGCTGTTTGCCA„

6797,AA102454„20,209,TAAGCTGTTTGCCACCTCAA„ 6798,AA102454„20,203,GTTTGCCACCTCAAAAACTT„ 6799,AA102454„20,197,CACCTCAAAAACTTTTATGA„ 6800,AA102454„20,191,AAAAACTTTTATGAACTTCA„ 6801,AA102454„20,185,TTTTATGAACTTCACCACCA„

6802,AA102454„20,179,GAACTTCACCACCACTAGTG„ 6803,AA102454„20,173,CACCACCACTAGTGTCTGTC„ 6804,AA 102454„20, 167,CACTAGTGTCTGTCCATGGA„ 6805,AA 102454„20, 161 ,TGTCTGTCCATGGAGTTAGA„ 6806,AA102454„20,155,TCCATGGAGTTAGAGGGGAC„

6807,AA102454„20,149,GAGTTAGAGGGGACATCACT„ 6808,AA102454„20,143,GAGGGGACATCACTTAGAAG„ 6809,AA102454„20,137,ACATCACTTAGAAGTTCTTA„ 6810,AA 102454„20, 131 ,CTTAGAAGTTCTTATAGAAA„ 6811,AA102454„20,125,AGTTCTTATAGAAAGGACAC„

6812,AA102454„20, 119,TATAGAAAGGACACAAGTTT„ 6813,AA102454„20,113,AAGGACACAAGTTTGTTTCC„ 6814,AA 102454„20, 107,ACAAGTTTGTTTCCTGGCTT„ 6815,AA 102454„20, 101 ,TTGTTTCCTGGCTTTACCTT„ 6816,AA 102454„20,95,CCTGGCTTTACCTTGGGAAA„

6817,AA102454„20,89,TTTACCTTGGGAAAATGCTA„ 6818,AA102454„20,83,TTGGGAAAATGCTAGCAACA„ 6819,AA102454„20,77,AAATGCTAGCAACATTACAG„ 6820_>AA102454„20,71,TAGCAACATTACAGAAATTT„ 6821,AA102454„20,65,CATTACAGAAATTTTGCCTT„

6822,AA102454„20,59,AGAAATTTTGCCTTGTTGCC„ 6823,AA102454„20,53,TTTGCCTTGTTGCCTTATCT„ 6824,AA102454„20,47,TTGTTGCCTTATCTTCTTCC„ 6825,AA102454„20,41,CCTTATCTTCTTCCAAATGT„ 6826,AA102454„20,35,CTTCTTCCAAATGTACTGTT„

6827,AA102454„20,29,CCAAATGTACTGTTAAATAA„ 6828,AA102454„20,23,GTACTGTTAAATAAAAATAA„ 6829,AA 102454„20, 17,TTAAATAAAAATAAANGGTT„ 6830,AA102454„20,11,AAAAATAAANGGTTACCCCA„ 6831,AA102454„20,5,AAANGGTTACCCCATGCAAT„

(GENBANK ACCESSION NO. AA258396)

GAGAAATAATGAATAAATTCTTAATGTTTTCCCCTCCACCGCCCTTTTTTATTCTCCAAGATTAGGAATTACTACGGATTAGGTTTTT AATCAAAATACATTAAAATAAAATTACAGTACATCATCGCTCCTAGAAAATTCACCATACAAGACGATCCTTTCAAAGGTTCATAAA

TAAAAGTCTTCTTGACTCGAAATCGTTTCCTGCATCGTGATGAAAAGTATGCAGAAAACTAAGAAGAATCGC (SEQ ID NO: 6832)

6833,AA258396„20,403,GCGATTCTTCTTAGTTTTCT„ 6834,AA258396„20,397,CTTCTTAGTTTTCTGCATAC„

6835,AA258396„20,391,AGTTTTCTGCATACTTTTCA„ 6836,AA258396„20,385,CTGCATACTTTTCATCACGA„ 6837,AA258396„20,379,ACTTTTCATCACGATGCAGG„ 6838,AA258396„20,373,CATCACGATGCAGGAAACGA„ 6839,AA258396„20,367,GATGCAGGAAACGATTTCGA„

6840,AA258396„20,361,GGAAACGATTTCGAGTCAAG„ 6841,AA258396„20,355,GATTTCGAGTCAAGAAGACT„ 6842,AA258396„20,349,GAGTCAAGAAGACTTTTATT„ 6843,AA258396„20,343,AGAAGACTTTTATTTATGAA„ 6844,AA2₅8396„20,337,CTTTTATTTATGAACCTTTG„

684₅,AA258396„20,331 ,TTTATGAACCTTTGAAAGGA„ 6846,AA258396„20,325,AACCTTTGAAAGGATCGTCT„ 6847,AA258396„20,319,TGAAAGGATCGTCTTGTATG„ 6848,AA258396„20,313,GATCGTCTTGTATGGTGAAT„ 6849,AA258396„20,307,CTTGTATGGTGAATTTTCTA„ 6850,AA258396„20,301,TGGTGAATTTTCTAGGAGCG„

6851 ,AA258396„20,295,ATTTTCTAGGAGCGATGATG„

6852,AA258396„20,289,TAGGAGCGATGATGTACTGT„

6853,AA258396„20,283,CGATGATGTACTGTAATTTT„ 6854,AA258396„20,277,TGTACTGTAATTTTATTTTA„

6855,AA258396„20,271,GTAATTTTATTTTAATGTAT„

6856,AA258396„20,265,TTATTTTAATGTATTTTGAT„

68₅7,AA258396„20,259,TAATGTATTTTGATTTATGA„

6858,AA258396„20,253,ATTTTGATTTATGATTATTT„ 6859,AA258396„20,247,ATTTATGATTATTTATTAGT„

6860,AA258396„20,241 ,GATTATTTATTAGTTTTTTT„

6861 ,AA258396„20,235,TTATTAGTTTTTTTTTAAAT„

6862,AA258396„20,229,GTTTTTTTTTAAATGCTTGT„

6863,AA258396„20,223,TTTTAAATGCTTGTTCTAAG„ 6864,AA258396„20,217,ATGCTTGTTCTAAGACATTT„

6865,AA258396„20,211,GTTCTAAGACATTTCTGAAT„

6866,AA258396„20,205,AGACATTTCTGAATGTAGAC„

6867,AA258396„20, 199,TTCTGAATGTAGACCATπT„

6868,AA258396„20,193,ATGTAGACCATTTTCCAAAA„ 6869,AA258396„20,187,ACCATTTTCCAAAAAGGAAA„

6870,AA258396„20, 181 TCCAAAAAGGAAACTTTAT,,

6871,AA258396„20,175,AAAGGAAACTTTATTTTCAA„

6872,AA258396„20,169,AACTTTATTTTCAAAAACCT„

6873,AA258396„20,163,ATTTTCAAAAACCTAATCCG„ 6874,AA258396„20,157,AAAAACCTAATCCGTAGTAA„

6875,AA258396,,20,151,CTAATCCGTAGTAATTCCTA„

6876,AA258396„20,145,CGTAGTAATTCCTAATCTTG„

6877,AA258396„20,139,AATTCCTAATCTTGGAGAAT„

6878,AA258396„20,133,TAATCTTGGAGAATAAAAAA„ 6879,AA258396„20,127,TGGAGAATAAAAAAGGGCGG„

6880,AA258396„20,121,ATAAAAAAGGGCGGTGGAGG„

6881,AA258396„20,115,AAGGGCGGTGGAGGGGAAAA„

6882,AA258396„20, 109,GGTGGAGGGGAAAACATTAA„

6883,AA258396„20,103,GGGGAAAACATTAAGAATTT„ 6884,AA258396„20,97,AACATTAAGAATTTATTCAT„

6885,AA258396„20,91,AAGAATTTATTCATTATTTC„

6886,AA258396„20,85,TTATTCATTATTTCTCGAGT„

6887,AA258396„20,79,ATTATTTCTCGAGTACTTTC„

6888,AA258396„20,73,TCTCGAGTACTTTCAGAAAG„ 6889,AA258396„20,67,GTACTTTCAGAAAGTCTGAC„

6890,AA258396„20,61,TCAGAAAGTCTGACACTTTC„

6891,AA258396„20,55,AGTCTGACACTTTCATTGTT„

6892,AA258396„20,49,ACACTTTCATTGTTGTGCCA„

6893,AA258396„20,43,TCATTGTTGTGCCAGCTGGT„ 6894,AA258396„20,37,TTGTGCCAGCTGGTTGAAAT„

6895,AA258396„20,31 ,CAGCTGGTTGAAATTAAAAC„

6896,AA258396„20,25,GTTGAAATTAAAACTCTGAT„

6897,AA258396„20,19,ATTAAAACTCTGATATTACT„

6898,AA258396„20,13,ACTCTGATATTACTTTTAAA„ 6899,AA258396„20,7,ATATTACTTTTAAAAAAAAA„

6900,AA258396„20, 1 ,CTTTTAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. AA497002)

TCTGGGACAATTAAGCTTTATTTTTCATATATATATATATTTTCATATATATATATACATACATATATAAAGGAAACAATTTGCAAAT

TTACACACCTGACAAAACCATATATACACACATATGTATGCATACACACAGACAGACACACACACCCGAAGCTCTAGCCAGGCCCG TTTTCCATCCCTAAGTACCATTCTCTCATTTGGGCCCTTCTAGGGTTGGGGCCCTGAGCTTGGTTTGTAGAAGTTTGGTGCTAATATA

ACCATAGCTTTAATCCCCATGAAGGACAGTGTAGACCTCATCTTTGTCTGCTCCCCGCTGCCTTTCAGTTTTACGTGATCCATCAAGA

GGGCTATGGGAGCCAGTGAACACGGCGGATTGAGGCTAATTCACCTGAACTCGAAAACAGTGCCCAGGGTGGGTGACGAAAGGGG

TCTTTTGAACTGTGGAAGGAACATCCAAGATCTCTGGTCCATGAAGATTGG

(SEQ ID NO: 6901)

6902,AA497002„20,467,CCAATCTTCATGGACCAGAG„

6903,AA497002„20,461,TTCATGGACCAGAGATCTTG„

6904,AA497002„20,4₅5,GACCAGAGATCTTGGATGTT„

6905,AA497002„20,449,AGATCTTGGATGTTCCTTCC„ 6906,AA497002„20,443,TGGATGTTCCTTCCACAGTT„

6907,AA497002„20,437,TTCCTTCCACAGTTCAAAAG„

6908,AA497002„20,431 ,CCACAGTTCAAAAGACCCCT„

6909,AA497002„20,425,TTCAAAAGACCCCTTTCGTC„

6910,AA497002„20,419,AGACCCCTTTCGTCACCCAC„ 6911 ,AA497002„20,413,CTTTCGTCACCCACCCTGGG„

6912,AA497002„20,407,TCACCCACCCTGGGCACTGT„

6913 , AA497002„20,401 , ACCCTGGGCACTGTTTTCGA,,

6914,AA497002„20,395,GGCACTGTTTTCGAGTTCAG„

6915,AA497002„20,389,GTTTTCGAGTTCAGGTGAAT„ 6916_JAA497002„20,383,GAGTTCAGGTGAATTAGCCT„ 6917,AA497002„20,377,AGGTGAATTAGCCTCAATCC„

6918,AA497002„20,371,ATTAGCCTCAATCCGCCGTG„

6919,AA497002„20,365,CTCAATCCGCCGTGTTCACT„

6920,AA497002„20,359,CCGCCGTGTTCACTGGCTCC„ 6921,AA497002„20,353,TGTTCACTGGCTCCCATAGC„

6922,AA497002„20,347,CTGGCTCCCATAGCCCTCTT„

6923,AA497002„20,341,CCCATAGCCCTCTTGATGGA„

6924,AA497002„20,335,GCCCTCTTGATGGATCACGT„

6925,AA497002„20,329,TTGATGGATCACGTAAAACT„ 6926,AA497002„20,323,GATCACGTAAAACTGAAAGG„

6927,AA497002„20,317,GTAAAACTGAAAGGCAGCGG„

6928,AA497002„20,311 ,CTGAAAGGCAGCGGGGAGCA„

6929,AA497002„20,305,GGCAGCGGGGAGCAGACAAA„

6930,AA497002„20,299,GGGGAGCAGACAAAGATGAG„ 6931,AA497002„20,293,CAGACAAAGATGAGGTCTAC„

6932,AA497002„20,287,AAGATGAGGTCTACACTGTC„

6933,AA497002„20,281,AGGTCTACACTGTCCTTCAT„

6934,AA497002„20,27₅,ACACTGTCCTTCATGGGGAT„

6935,AA497002„20,269,TCCTTCATGGGGATTAAAGC„ 6936,AA497002„20,263,ATGGGGATTAAAGCTATGGT„

6937,AA497002„20,257,ATTAAAGCTATGGTTATATT„

6938,AA497002„20,251,GCTATGGTTATATTAGCACC„

6939,AA497002„20,245,GTTATATTAGCACCAAACTT„

6940,AA497002„20,239,TTAGCACCAAACTTCTACAA„ 6941,AA497002„20,233,CCAAACTTCTACAAACCAAG„

6942,AA497002„20,227,TTCTACAAACCAAGCTCAGG„

6943,AA497002„20,221,AAACCAAGCTCAGGGCCCCA„

6944,AA497002„20,215,AGCTCAGGGCCCCAACCCTA„

6945,AA497002„20,209,GGGCCCCAACCCTAGAAGGG„ 6946,AA497002„20,203,CAACCCTAGAAGGGCCCAAA„

6947,AA497002„20, 197,TAGAAGGGCCCAAATGAGAG„

6948,AA497002„20,191,GGCCCAAATGAGAGAATGGT„

6949,AA497002„20, 185,AATGAGAGAATGGTACTTAG„

6950,AA497002„20,179,AGAATGGTACTTAGGGATGG„ 6951 ,AA497002„20, 173,GTACTTAGGGATGGAAAACG„

6952,AA497002„20, 167,AGGGATGGAAAACGGGCCTG„

6953,AA497002„20, 161.GGAAAACGGGCCTGGCTAGA,,

6954,AA497002„20, 155,CGGGCCTGGCTAGAGCTTCG„

6955,AA497002„20,149,TGGCTAGAGCTTCGGGTGTG„ 6956,AA497002„20,143,GAGCTTCGGGTGTGTGTGTC„

6957,AA497002„20, 137,CGGGTGTGTGTGTCTGTCTG„

6958,AA497002„20, 131 ,TGTGTGTCTGTCTGTGTGTA„

6959,AA497002„20,125,TCTGTCTGTGTGTATGCATA„

6960,AA497002„20, 119,TGTGTGTATGCATACATATG„ 6961,AA497002„20,113,TATGCATACATATGTGTGTA„

6962,AA497002„20,107,TACATATGTGTGTATATATG„

6963,AA497002„20, 101 ,TGTGTGTATATATGGTTTTG„

6964,AA497002„20,95,TATATATGGTTTTGTCAGGT„

696₅,AA497002„20,89,TGGTTTTGTCAGGTGTGTAA„ 6966,AA497002„20,83,TGTCAGGTGTGTAAATTTGC„

6967,AA497002„20,77,GTGTGTAAATTTGCAAATTG„

6968,AA497002„20,71 ,AAATTTGCAAATTGTTTCCT„

6969,AA497002„20,6₅,GCAAATTGTTTCCTTTATAT„

6970,AA497002„20,₅9,TGTTTCCTTTATATATGTAT„ 6971,AA497002„20,53,CTTTATATATGTATGTATAT„

6972,AA497002„20,47,ATATGTATGTATATATATAT„

6973,AA497002„20,41 ,ATGTATATATATATATGAAA„

6974,AA497002„20,35,ATATATATATGAAAATATAT„

6975,AA497002„20,29,ATATGAAAATATATATATAT„ 6976,AA497002„20,23,AAATATATATATATATGAAA„

6977,AA497002„20, 17,ATATATATATGAAAAATAAA„

6978,AA497002„20, 11 ,ATATGAAAAATAAAGCTTAA„

6979,AA497002„20,5,AAAATAAAGCTTAATTGTCC„

(GENBANK ACCESSION NO. AA282906) AAAATGGTCGCTACAGCATCTCTCGGACGGAGGCCGCTGACCTCTGCAAGGCTTTCAATAGCACCTTGCCCACAATGGCCCAGATG

GAGAAAGCTCTGAGCATCGGATTTGAGACCTGCAGGTATGGGTTCATAGAAGGGCACGTGGTGATTCCCCGGATCCACCCCAACTC

CATCTGTGCAGCAAACAACACAGGGGTGTACATCCTCACATCCAACACCTCCCAGTATGACACATATTGCTTCAATGCTTCAGCTCC

ACCTGAAGAAGATTGTACATCAGTCACAGACCTGCCCAATGCCTTTGATGGACCAATTACCATAACTATTGTTAACCGTGATGGCAC

CCGCTATGTCCAGAAAGGAGAATACAGAACGAATCCTGAAGACATCTACCCCAGCAACCCTACTGGATGATGACGTGAGCAGCGGC TCCTCCAGTGAAAGGAGCAGCACTTCAGGAGGTTACATCTTTTACACTTTTTCTACTGTACACCCATCCCAGACGAAGACAGTCCTT

GGATCACGACAGCACAGCAGATCCTGCTAC

(SEQ LD NO: 6980)

6981,AA282906„20,530,GTAGCAGGATCTGCTGTGCT„ 6982,AA282906„20,524,GGATCTGCTGTGCTGTCGTG„ 6983,AA282906„20,518,GCTGTGCTGTCGTGATCCAA„ 6984,AA282906„20,512,CTGTCGTGATCCAAGGACTG„ 6985,AA282906„20,506,TGATCCAAGGACTGTCTTCG„ 6986,AA282906„20,500,AAGGACTGTCTTCGTCTGGG„ 6987,AA282906„20,494,TGTCTTCGTCTGGGATGGGT„

6988,AA282906„20,488,CGTCTGGGATGGGTGTACAG„ 6989,AA282906„20,482,GGATGGGTGTACAGTAGAAA„ 6990,AA282906„20,476,GTGTACAGTAGAAAAAGTGT„ 6991,AA282906„20,470,AGTAGAAAAAGTGTAAAAGA„ 6992,AA282906„20,464,AAAAGTGTAAAAGATGTAAC„

6993,AA282906„20,458,GTAAAAGATGTAACCTCCTG„ 6994,AA282906„20,452,GATGTAACCTCCTGAAGTGC„ 6995,AA282906„20,446,ACCTCCTGAAGTGCTGCTCC„ 6996,AA282906„20,440,TGAAGTGCTGCTCCTTTCAC„ 6997,AA282906„20,434,GCTGCTCCTTTCACTGGAGG„

6998,AA282906„20,428,CCTTTCACTGGAGGAGCCGC„ 6999,AA282906„20,422,ACTGGAGGAGCCGCTGCTCA„ 7000,AA282906„20,416,GGAGCCGCTGCTCACGTCAT„ 7001,AA282906„20,410,GCTGCTCACGTCATCATCCA„ 7002,AA282906„20,404,CACGTCATCATCCAGTAGGG„

7003,AA282906„20,398,ATCATCCAGTAGGGTTGCTG„ 7004,AA282906„20,392,CAGTAGGGTTGCTGGGGTAG„ 7005,AA282906„20,386,GGTTGCTGGGGTAGATGTCT„ 7006,AA282906„20,380,TGGGGTAGATGTCTTCAGGA„ 7007,AA282906„20,374,AGATGTCTTCAGGATTCGTT„

7008,AA282906„20,368,CTTCAGGATTCGTTCTGTAT„ 7009,AA282906„20,362,GATTCGTTCTGTATTCTCCT„ 7010,AA282906„20,356,TTCTGTATTCTCCTTTCTGG„ 7011,AA282906„20,350,ATTCTCCTTTCTGGACATAG„ 7012,AA282906„20,344,CTTTCTGGACATAGCGGGTG„

7013,AA282906„20,338,GGACATAGCGGGTGCCATCA„ 7014,AA282906„20,332,AGCGGGTGCCATCACGGTTA„ 7015,AA282906„20,326,TGCCATCACGGTTAACAATA„ 7016,AA282906„20,320,CACGGTTAACAATAGTTATG„ 7017,AA282906„20,314,TAACAATAGTTATGGTAATT„

7018,AA282906„20,308,TAGTTATGGTAATTGGTCCA„ 7019,AA2S2906„20,302,TGGTAATTGGTCCATCAAAG„ 7020,AA282906„20,296,TTGGTCCATCAAAGGCATTG„ 7021 ,AA282906„20,290,CATCAAAGGCATTGGGCAGG„ 7022,AA282906„20,284,AGGCATTGGGCAGGTCTGTG„

7023,AA282906„20,278,TGGGCAGGTCTGTGACTGAT„ 7024,AA282906„20,272,GGTCTGTGACTGATGTACAA„ 7025,AA282906„20,266,TGACTGATGTACAATCTTCT„ 7026,AA282906„20,260,ATGTACAATCTTCTTCAGGT„ 7027,AA282906„20,254,AATCTTCTTCAGGTGGAGCT„

7028,AA282906„20,248,CTTCAGGTGGAGCTGAAGCA„ 7029,AA282906„20,242,GTGGAGCTGAAGCATTGAAG„ 7030,AA282906„20,236,CTGAAGCATTGAAGCAATAT„ 7031 ,AA282906„20,230,CATTGAAGCAATATGTGTCA„ 7032,AA282906„20,224,AGCAATATGTGTCATACTGG„

7033,AA282906„20,218,ATGTGTCATACTGGGAGGTG„ 7034,AA282906„20,212,CATACTGGGAGGTGTTGGAT„ 7035,AA282906„20,206,GGGAGGTGTTGGATGTGAGG„ 7036,AA282906„20,200,TGTTGGATGTGAGGATGTAC„ 7037,AA282906„20,194,ATGTGAGGATGTACACCCCT„

7038,AA282906„20, 188,GGATGTACACCCCTGTGTTG„ 7039,AA282906„20, 182,ACACCCCTGTGTTGTTTGCT„ 7040,AA282906„20, 176,CTGTGTTGTTTGCTGCACAG„ 7041,AA282906„20,170,TGTTTGCTGCACAGATGGAG„ 7042,AA282906„20, 164,CTGCACAGATGGAGTTGGGG„

7043,AA282906„20, 158,AGATGGAGTTGGGGTGGATC„ 7044,AA282906„20, 1₅2,AGTTGGGGTGGATCCGGGGA„ 704₅,AA282906„20,146,GGTGGATCCGGGGAATCACC„ 7046,AA282906„20,140,TCCGGGGAATCACCACGTGC„ 7047,AA282906„20, 134.GAATCACCACGTGCCCTTCT,,

7048,AA282906„20,128,CCACGTGCCCTTCTATGAAC„ 7049₎AA282906„20,122,GCCCTTCTATGAACCCATAC„ 70₅0,AA282906„20, 116.CTATGAACCCATACCTGCAG,, 70₅1,AA282906„20,110,ACCCATACCTGCAGGTCTCA„ 7052,AA282906„20,104,ACCTGCAGGTCTCAAATCCG„

7053,AA282906„20,98,AGGTCTCAAATCCGATGCTC„ 7054,AA282906„20,92,CAAATCCGATGCTCAGAGCT„ 70₅₅,AA282906„20,86,CGATGCTCAGAGCTTTCTCC„ 70₅6,AA282906„20,80,TCAGAGCTTTCTCCATCTGG„ 7057,AA282906„20,74,CTTTCTCCATCTGGGCCATT„ 7058,AA282906„20,68,CCATCTGGGCCATTGTGGGC„

7059,AA282906„20,62,GGGCCATTGTGGGCAAGGTG„

7060,AA282906„20,56,TTGTGGGCAAGGTGCTATTG„

7061,AA282906„20,50,GCAAGGTGCTATTGAAAGCC„ 7062,AA282906„20,44,TGCTATTGAAAGCCTTGCAG„

7063,AA282906„20,38,TGAAAGCCTTGCAGAGGTCA„

7064,AA282906„20,32,CCTTGCAGAGGTCAGCGGCC„

7065,AA282906„20,26,AGAGGTCAGCGGCCTCCGTC„

7066,AA282906„20,20,CAGCGGCCTCCGTCCGAGAG„ 7067,AA282906„20,14,CCTCCGTCCGAGAGATGCTG„

7068,AA282906„20,8,TCCGAGAGATGCTGTAGCGA„

7069,AA282906„20,2,AGATGCTGTAGCGACCATTT„

(GENBANK ACCESSION NO AA156940)

ATTTTGCATAACAAGTTTATTTTTTTAAAAGGCATATAGACAATAAACAAAGTAAATAATCAGATCTTAACTTCTGTCCTAGACTTGT TCCGTTAAGTTCTAGTCTGTGAGCACTTGTAGTTCAATAATCGTCATCTTCATCAGAGTCCATTACTTTTCTTCTGTTGAATTTCACTG

TTGTTGTCTTTTCTGTTTGTTGGCTTACTTTTTTAAGGATTTCTATTAAACCTTGTTCTGATACCTTCTCACTTAGTTGTCCATATCTTG

CCATCTGTATAAGGTAATTCTCTACTGCTTTAGTTTTTTCAGGCTTTACAAGTGCTAAGTTACTTAACCTGGCCCGGGCCGACTGATC

CAGAACTTGGGCTAAGATACTGTTTCTCANTTCTGCTTCCCTGTGCTTGCTTCCTGTTGGGCCGCATCACCAGGATCCCCGTGTTTGG

CCGCAGCTCGGCCAGNCTCTGTCTCCTCAGCGCCTCAAGCTCCTCGGTCNGCCATGGGCTCGGCGTCAGGCTGGGANGCAGCCGCG TTCANTCTCGCCTCGTGCC

(SEQ ID NO 7070)

7071 ,AA156940„20,529,GGCACGAGGCGAGANTGAAC„

7072,AA156940„20,523,AGGCGAGANTGAACGCGGCT„ 7073,AA156940„20,517,GANTGAACGCGGCTGCNTCC„

7074.AA156940„20,511 ,ACGCGGCTGCNTCCCAGCCT„

7075,AA156940„20,505,CTGCNTCCCAGCCTGACGCC„

7076,AA156940„20,499,CCCAGCCTGACGCCGAGCCC„

7077,AA1₅6940„20,493,CTGACGCCGAGCCCATGGCN„ 7078,AA156940„20,487,CCGAGCCCATGGCNGACCGA„

7079,AA156940„20,481,CCATGGCNGACCGAGGAGCT„

7080,AA1₅6940„20,475,CNGACCGAGGAGCTTGAGGC„

7081,AA156940„20,469,GAGGAGCTTGAGGCGCTGAG„

7082,AA1₅6940„20,463,CTTGAGGCGCTGAGGAGACA„ 7083,AA1₅6940„20,4₅7,GCGCTGAGGAGACAGAGNCT„

7084,AA156940„20,451,AGGAGACAGAGNCTGGCCGA„

7085,AA156940„20,445,CAGAGNCTGGCCGAGCTGCG„

7086,AA1₅6940„20,439,CTGGCCGAGCTGCGGCCAAA„

7087,AA1₅6940„20,433,GAGCTGCGGCCAAACACGGG„ 7088,AA156940„20,427,CGGCCAAACACGGGGATCCT„

7089,AA156940„20,421,AACACGGGGATCCTGGTGAT„

7090,AA1₅6940„20,41₅,GGGATCCTGGTGATGCGGCC„

7091 ,AA156940„20,409,CTGGTGATGCGGCCCAACAG„

7092,AA156940„20,403,ATGCGGCCCAACAGGAAGCA„ 7093.AA156940„20,397,CCCAACAGGAAGCAAGCACA„

7094,AA156940„20,391,AGGAAGCAAGCACAGGGAAG„

7095,AA1₅6940„20,385,CAAGCACAGGGAAGCAGAAN„

7096,AA156940„20,379,CAGGGAAGCAGAANTGAGAA„

7097,AA1₅6940„20,373,AGCAGAANTGAGAAACAGTA„ 7098.AA1₅6940„20,367,ANTGAGAAACAGTATCTTAG„

7099,AA1₅6940„20,361,AAACAGTATCTTAGCCCAAG„

7100,AA1₅6940„20,355,TATCTTAGCCCAAGTTCTGG„

7101,AA1₅6940„20,349,AGCCCAAGTTCTGGATCAGT„

7102,AA156940„20,343,AGTTCTGGATCAGTCGGCCC„ 7103,AA1₅6940„20,337,GGATCAGTCGGCCCGGGCCA„

7104.AA156940„20,331 ,GTCGGCCCGGGCCAGGTTAA„

7105,AA156940„20,325,CCGGGCCAGGTTAAGTAACT„

7106,AA156940„20,319,CAGGTTAAGTAACTTAGCAC„

7107,AA156940„20,313,AAGTAACTTAGCACTTGTAA„ 7108,AA156940„20,307,CTTAGCACTTGTAAAGCCTG„

7109,AA156940„20,301,ACTTGTAAAGCCTGAAAAAA„

7110,AA156940„20,295 AAGCCTGAAAAAACTAAAG„

7111,AA156940„20,289,TGAAAAAACTAAAGCAGTAG„

7112,AA156940„20,283,AACTAAAGCAGTAGAGAATT„ 7113,AA156940„20,277,AGCAGTAGAGAATTACCTTA„

7114,AA156940„20,271,AGAGAATTACCTTATACAGA„

7115,AA156940„20,265,TTACCTTATACAGATGGCAA„

7116,AA1₅6940„20,259,TATACAGATGGCAAGATATG„

7117,AA1₅6940„20,253,GATGGCAAGATATGGACAAC„ 7118,AA1₅6940„20,247,AAGATATGGACAACTAAGTG„

7119,AA1₅6940„20,241,TGGACAACTAAGTGAGAAGG„

7120,AA156940„20,235,ACTAAGTGAGAAGGTATCAG„

7121,AA156940„20,229,TGAGAAGGTATCAGAACAAG„

7122,AA1₅6940„20,223,GGTATCAGAACAAGGTTTAA„ 7123,AA156940„20,217,AGAACAAGGTTTAATAGAAA„ 7124.AA156940„20,211 ,AGGTTTAATAGAAATCCTTA„

7125,AA156940„20,205,AATAGAAATCCTTAAAAAAG„

7126.AA156940„20, 199,AATCCTTAAAAAAGTAAGCC„

7127,AA156940„20,193,TAAAAAAGTAAGCCAACAAA„ 7128.AA156940„20, 187,AGTAAGCCAACAAACAGAAA„

7129,AA156940„20,181,CCAACAAACAGAAAAGACAA„

7130,AA156940„20,175,AACAGAAAAGACAACAACAG„

7131 ,AA156940„20, 169,AAAGACAACAACAGTGAAAT„

7132.AA156940„20, 163,AACAACAGTGAAATTCAACA„ 7133,AA156940„20,157,AGTGAAATTCAACAGAAGAA„

7134.AA156940„20,151 ,ATTCAACAGAAGAAAAGTAA„

7135,AA156940„20,145,CAGAAGAAAAGTAATGGACT„

7136,AA156940„20,139,AAAAGTAATGGACTCTGATG„

7137,AA156940„20,133,AATGGACTCTGATGAAGATG„ 7138,AA156940„20,127,CTCTGATGAAGATGACGATT„

7139.AA 156940„20, 121 ,TGAAGATGACGATTATTGAA„

7140,AA156940„20,115,TGACGATTATTGAACTACAA„

7141,AA156940„20,109,TTATTGAACTACAAGTGCTC„

7142,AA 156940„20, 103,AACTACAAGTGCTCACAGAC„ 7143,AA156940„20,97,AAGTGCTCACAGACTAGAAC„

7144,AA156940„20,91 ,TCACAGACTAGAACTTAACG„

7145,AA156940„20,85,ACTAGAACTTAACGGAACAA„

7146,AA156940„20,79,ACTTAACGGAACAAGTCTAG„

7147,AA156940„20,73,CGGAACAAGTCTAGGACAGA„ 7148,AA156940„20,67,AAGTCTAGGACAGAAGTTAA„

7149,AA156940„20,61,AGGACAGAAGTTAAGATCTG„

7150,AA156940„20,55,GAAGTTAAGATCTGATTATT„

7151 ,AA156940„20,49,AAGATCTGATTATTTACTTT„

7152,AA156940„20,43,TGATTATTTACTTTGTTTAT„ 7153,AA156940„20,37,TTTACTTTGTTTATTGTCTA„

7154,AA156940„20,31 ,TTGTTTATTGTCTATATGCC„

7155.AA156940„20,25,ATTGTCTATATGCCTTTTAA„

7156,AA156940„20,19,TATATGCCTTTTAAAAAAAT„

7157,AA156940„20, 13.CCTTTTAAAAAAATAAACTT,, 7158,AA156940„20,7,AAAAAAATAAACTTGTTATG„

7159.AA156940„20, 1 ,ATAAACTTGTTATGCAAAAT„

(GENBANK ACCESSION NO. AA485272)

GACACGGCTCACAAAGCGGTGGGAAATTCCAGTGATGGCATTGTTTGTTGGTTGGTTCCTTTTATCCAAATGGAGACAAGACACATT

TCCGCAGGACTGTCCACCTCCCCCCACGAGACAAACAGAATGCAAGACTGTCACACGCGGCTAGGACTGGTTCCACGGACACACGA TTTTGTGGCATTGACACACCACGATGCGATGCCAGGCCACAGTGGGTGCCAGGAGGGGAGGAAGCAGCTAATGCTATGCCCACACT

CGCCTTCAGGACGTGCCCCGGGAAGAGGCCCGGCAGTGTCTGCTGGTGATAA

(SEQ ID NO: 7160)

7161 ,AA485272„20,292,TTATCACCAGCAGACACTGC„ 7162,AA485272„20,286,CCAGCAGACACTGCCGGGCC„

7163,AA485272„20,280,GACACTGCCGGGCCTCTTCC„

7164,AA485272„20,274,GCCGGGCCTCTTCCCGGGGC„

7165,AA485272„20,268,CCTCTTCCCGGGGCACGTCC„

7166,AA485272„20,262,CCCGGGGCACGTCCTGAAGG„ 7167,AA485272„20,256,GCACGTCCTGAAGGCGAGTG„

7168,AA485272„20,250,CCTGAAGGCGAGTGTGGGCA„

7169,AA485272„20,244,GGCGAGTGTGGGCATAGCAT„

7170,AA485272„20,238,TGTGGGCATAGCATTAGCTG„

7171,AA485272„20,232,CATAGCATTAGCTGCTTCCT„ 7172,AA48₅272„20,226,ATTAGCTGCTTCCTCCCCTC„

7173,AA48₅272„20,220,TGCTTCCTCCCCTCCTGGCA„

7174,AA485272„20,214,CTCCCCTCCTGGCACCCACT„

7175,AA485272„20,208,TCCTGGCACCCACTGTGGCC„

7176,AA485272„20,202,CACCCACTGTGGCCTGGCAT„ 7177,AA485272„20,196,CTGTGGCCTGGCATCGCATC„

7178,AA485272„20,190,CCTGGCATCGCATCGTGGTG„

7179,AA485272„20,184,ATCGCATCGTGGTGTGTCAA„

7180,AA485272„20, 178,TCGTGGTGTGTCAATGCCAC„

7181 ,AA485272„20, 172,TGTGTCAATGCCACAAAATC„ 7182,AA485272„20, 166.AATGCCACAAAATCGTGTGT,,

7183,AA485272„20, 160,ACAAAATCGTGTGTCCGTGG„

7184,AA485272„20, 154,TCGTGTGTCCGTGGAACCAG„

7185,AA485272„20, 148,GTCCGTGGAACCAGTCCTAG„

7186,AA485272„20,142,GGAACCAGTCCTAGCCGCGT„ 7187,AA485272„20,136,AGTCCTAGCCGCGTGTGACA„

7188,AA485272„20, 130,AGCCGCGTGTGACAGTCTTG„

7189,AA485272„20,124,GTGTGACAGTCTTGCATTCT„

7190,AA485272,,20,118,CAGTCTTGCATTCTGTTTGT„

7191,AA485272„20,112,TGCATTCTGTTTGTCTCGTG„ 7192,AA485272„20,106,CTGTTTGTCTCGTGGGGGGA„ 7193,AA485272„20, 100,GTCTCGTGGGGGGAGGTGGA„

7194,AA485272„20,94,TGGGGGGAGGTGGACAGTCC„

7195,AA485272„20,88,GAGGTGGACAGTCCTGCGGA„

7196,AA485272„20,82,GACAGTCCTGCGGAAATGTG„ 7197,AA485272„20,76,CCTGCGGAAATGTGTCTTGT„

7198,AA485272,,20,70,GAAATGTGTCTTGTCTCCAT„

7199,AA485272„20,64,TGTCTTGTCTCCATTTGGAT„

7200,AA485272„20,58,GTCTCCATTTGGATAAAAGG„

7201,AA485272„20,52,ATTTGGATAAAAGGAACCAA„ 7202_JAA485272„20,46,ATAAAAGGAACCAACCAACA„

7203,AA485272„20,40,GGAACCAACCAACAAACAAT„

7204,AA485272„20,34,AACCAACAAACAATGCCATC„

7205,AA485272„20,28,CAAACAATGCCATCACTGGA„

7206_>AA485272„20,22,ATGCCATCACTGGAATTTCC„ 7207,AA485272„20, 16,TCACTGGAATTTCCCACCGC„

7208,AA485272„20,10,GAATTTCCCACCGCTTTGTG„

7209,AA48₅272„20,4,CCCACCGCTTTGTGAGCCGT„

(GENBANK ACCESSION NO. R199₅6)

CCATGCAGATTATGCGGATCAAACCTCACCAAGGCCAGCACATAGGAGAGATGAGCTTCCTACAGCACAACAAATGTGAATGCAGA CCAAAGAAAGATAGAGCAAGACAAGAAAAATGTGACAAGCCGAGGCGNTGAGCGNGCAGGAGGAAGGAGCCTCCCTCAGGGTTT

CGGGAACCAGATCTCTCACCAGGAAAGACTGATACAGAACGATCGATACAGAAACCACGCTGCCGCCACCACACCATCACCATTCG

ACAGAACAGTCCTTAATCCAGAAACCTGAAATTGAAGGAAGAGGGAGACTCTTGCGCAGAGCACTTTTGGGGTCCGGAGGGCGGA

GATTCCGGCGGGAAGATTTTCCCGGGCGGGTTGACCCAGGCNTGGTCCNTTTTNGGATTTNGGGTTTTCGCCNTTTTATTTTTTTCTT (SEQ ID NO: 7210)

7211 ,R19956„20,479,AATCTAAGGGAAACCCAAAA„

7212,R19956„20,473,AGGGAAACCCAAAAAAANAA„

7213,R19956„20,467,ACCCAAAAAAANAAAANTCT„ 7214.R19956„20,461 ,AAAAANAAAANTCTCCTAAA„

7215,R19956„20,455,AAAANTCTCCTAAACTTCCG„

7216,R19956„20,449,CTCCTAAACTTCCGGGCCTC„

7217,R19956„20,443,AACTTCCGGGCCTCNGGTGA„

7218,R19956„20,437,CGGGCCTCNGGTGAATTTAA„ 7219,R19956„20,431 ,TCNGGTGAATTTAAACAANC„

7220,R19956„20,42₅,GAATTTAAACAANCCAAGAA„

7221 ,R19956„20,419,AAACAANCCAAGAAAAAAAT„

7222,R19956„20,413,NCCAAGAAAAAAATAAAANG„

7223,R19956„20,407,AAAAAAATAAAANGGCGAAA„ 7224.R19956„20,401 ,ATAAAANGGCGAAAACCCNA„

7225,R19956„20,395,NGGCGAAAACCCNAAATCCN„

7226,R19956„20,389,AAACCCNAAATCCNAAAANG„

7227,R19956„20,383,NAAATCCNAAAANGGACCAN„

722S,R19956„20,377,CNAAAANGGACCANGCCTGG„ 7229,R19956„20,371,NGGACCANGCCTGGGTCAAC„

7230,R19956„20,365,ANGCCTGGGTCAACCCGCCC„

7231,R19956„20,359,GGGTCAACCCGCCCGGGAAA„

7232,R19956„20,353,ACCCGCCCGGGAAAATCTTC„

7233,R19956„20,347,CCGGGAAAATCTTCCCGCCG„ 7234,R19956„20,341,AAATCTTCCCGCCGGAATCT„

7235,R19956„20,335,TCCCGCCGGAATCTCCGCCC„

7236,R19956„20,329,CGGAATCTCCGCCCTCCGGA„

7237,R19956„20,323,CTCCGCCCTCCGGACCCCAA„

7238,R19956„20,317,CCTCCGGACCCCAAAAGTGC„ 7239,R19956„20,311 ,GACCCCAAAAGTGCTCTGCG„

7240,R199₅6„20,30₅,AAAAGTGCTCTGCGCAAGAG„

7241,R199₅6„20,299,GCTCTGCGCAAGAGTCTCCC„

7242,R19956„20,293,CGCAAGAGTCTCCCTCTTCC„

7243,R19956„20,287,AGTCTCCCTCTTCCTTCAAT„ 7244.R19956„20,281 ,CCTCTTCCTTCAATTTCAGG„

7245,R19956„20,275₎CCTTCAATTTCAGGTTTCTG„

7246,R19956„20,269,ATTTCAGGTTTCTGGATTAA„

7247,R19956„20,263,GGTTTCTGGATTAAGGACTG„

7248,R19956„20,257,TGGATTAAGGACTGTTCTGT„ 7249,R19956„20,251 ,AAGGACTGTTCTGTCGAATG„

7250,R19956„20,245,TGTTCTGTCGAATGGTGATG„

7251 ,R19956„20,239,GTCGAATGGTGATGGTGTGG„

7252,R19956„20,233,TGGTGATGGTGTGGTGGCGG„

7253,R19956„20,227,TGGTGTGGTGGCGGCAGCGT„ 7254,R19956„20,221,GGTGGCGGCAGCGTGGTTTC„

7255,R19956„20,215,GGCAGCGTGGTTTCTGTATC„

7256,R19956„20,209,GTGGTTTCTGTATCGATCGT„

7257,R19956„20,203_>TCTGTATCGATCGTTCTGTA„

7258.R19956„20, 197,TCGATCGTTCTGTATCAGTC„ 7259,R19956„20,191,GTTCTGTATCAGTCTTTCCT„ 7260.R19956„20, 185,TATCAGTCTTTCCTGGTGAG„

7261,R19956„20,179,TCTTTCCTGGTGAGAGATCT„

7262,R19956„20,173,CTGGTGAGAGATCTGGTTCC„

7263,R19956„20,167,AGAGATCTGGTTCCCGAAAC„ 7264,R19956„20,161,CTGGTTCCCGAAACCCTGAG„

7265,R19956„20,155,CCCGAAACCCTGAGGGAGGC„

7266,R19956„20,149,ACCCTGAGGGAGGCTCCTTC„

7267,R19956„20,143,AGGGAGGCTCCTTCCTCCTG„

7268,R19956,,20,137,GCTCCTTCCTCCTGCNCGCT„ 7269,R19956„20,131,TCCTCCTGCNCGCTCANCGC„

7270,R19956„20,125,TGCNCGCTCANCGCCTCGGC„

7271 ,R19956„20, 119,CTCANCGCCTCGGCTTGTCA„

7272,R19956„20, 113,GCCTCGGCTTGTCACATTTT„

7273,R19956„20,107,GCTTGTCACATTTTTCTTGT„ 7274.R19956„20, 101 ,CACATTTTTCTTGTCTTGCT„

7275,R19956„20,95,TTTCTTGTCTTGCTCTATCT„

7276,R19956„20,89,GTCTTGCTCTATCTTTCTTT„

7277,R19956„20,83,CTCTATCTTTCTTTGGTCTG„

7278,R19956„20,77,CTTTCTTTGGTCTGCATTCA„ 7279.R19956„20,71 ,TTGGTCTGCATTCACATTTG„

7280,R19956„20,65,TGCATTCACATTTGTTGTGC„

7281 ,R19956„20,59,CACATTTGTTGTGCTGTAGG„

7282,R19956„20,53,TGTTGTGCTGTAGGAAGCTC„

7283,R19956„20,47,GCTGTAGGAAGCTCATCTCT„ 7284,R19956„20,41,GGAAGCTCATCTCTCCTATG„

7285,R19956,,20,35,TCATCTCTCCTATGTGCTGG„

7286,R19956„20,29,CTCCTATGTGCTGGCCTTGG„

7287,R19956„20,23,TGTGCTGGCCTTGGTGAGGT„

7288,R19956„20,17,GGCCTTGGTGAGGTTTGATC„ 7289,R19956„20,11,GGTGAGGTTTGATCCGCATA„

7290,R19956„20,5,GTTTGATCCGCATAATCTGC„

(GENBANK ACCESSION NO. AA463610)

AAACTAGGTAAAATTTGTTGTTGGTTCCTTTTAGACCACGGCTGCCCCTTCCACACCCCATCTTGCTCTAATGATCAAAACATGCTTG

AATAACTGAGCTTAGAGTATACCTCCTATATGTCCATTTAAGTCAGGAGAGGGGGCGATATAGAGACTAAGGCACAAAATTTTGTTT AAAACTCAGAATATAACATGTAAAATCCCATCTGCTAGAAGCCCATCCTGTGCCAGAGGAAGGAAAAGGAGGAAATTTCCTTTCTC

TTTTAGGAGGCACAACAGTTCTCTTCTAGGATTTGTTTGGCTGACTGGCAGTAACCTAGTGAATTTTTGAAAGATGAGTAATTTCTTT

GGCAACCTTCCTCCTCCCTTACTGAACCACTCTCCCACCTCCTGGTGGTACCATTATTATAGAAGCCCTCTACAGCCTGACTTTCTCT

CCAGCGGTCCAAAGTTATCCCCTCCTTTACCCCTCATCCAAAGTTCGCACTCCTTCAGGACAGCTGCTGTGCATTAGATATTAGGGG

GGAAAGTCATCTGTNTAATTTACACACTTGCATGAATTACTGGATATAACTCCTTAACTCAGGGAGCTATGTCATTTAGTGCTAACA AAGTAGAAAAATAGCTCGAGTGAGTTCTAATGGTGGA

(SEQ ID NO: 7291)

7292,AA463610„20,629,TCCACCATTAGAACTCACTC„ 7293,AA463610„20,623,ATTAGAACTCACTCGAGCTA„ 7294,AA463610„20,617,ACTCACTCGAGCTATTTTTC„

7295,AA463610„20,611,TCGAGCTATTTTTCTACTTT„ 7296,AA463610„20,605,TATTTTTCTACTTTGTTAGC„ 7297,AA463610„20,₅99,TCTACTTTGTTAGCACTAAA„ 7298,AA463610„20,₅93,TTGTTAGCACTAAATGACAT„ 7299,AA463610„20,₅87,GCACTAAATGACATAGCTCC„

7300,AA463610„20,₅81,AATGACATAGCTCCCTGAGT„ 7301,AA463610„20,575,ATAGCTCCCTGAGTTAAGGA„ 7302,AA463610„20,569,CCCTGAGTTAAGGAGTTATA„ 7303,AA463610„20,₅63,GTTAAGGAGTTATATCCAGT„ 7304,AA463610„20,₅₅7,GAGTTATATCCAGTAATTCA„

7305,AA463610„20,551,TATCCAGTAATTCATGCAAG„ 7306,AA463610„20,545,GTAATTCATGCAAGTGTGTA„ 7307,AA463610„20,539,CATGCAAGTGTGTAAATTAN„ 7308,AA463610„20,533,AGTGTGTAAATTANACAGAT„ 7309,AA463610„20,527,TAAATTANACAGATGACTTT„

7310,AA463610„20,521,ANACAGATGACTTTCCCCCC„ 7311.AA463610„20,515,ATGACTTTCCCCCCTAATAT„ 7312,AA463610„20,509,TTCCCCCCTAATATCTAATG„ 7313,AA463610„20,503,CCTAATATCTAATGCACAGC„ 7314,AA463610„20,497,ATCTAATGCACAGCAGCTGT„

7315,AA463610„20,491,TGCACAGCAGCTGTCCTGAA„ 7316,AA463610„20,485,GCAGCTGTCCTGAAGGAGTG„ 7317,AA463610„20,479,GTCCTGAAGGAGTGCGAACT„ 7318.AA463610„20,473,AAGGAGTGCGAACTTTGGAT„ 7319.AA463610„20,467,TGCGAACTTTGGATGAGGGG„

7320,AA463610„20,461 ,CTTTGGATGAGGGGTAAAGG„ 7321 ,AA463610„20,455,ATGAGGGGTAAAGGAGGGGA„ 7322,AA463610„20,449,GGTAAAGGAGGGGATAACTT„ 7323,AA463610„20,443,GGAGGGGATAACTTTGGACC„ 7324,AA463610„20,437,GATAACTTTGGACCGCTGGA„ 732₅,AA463610„20,431 ,TTTGGACCGCTGGAGAGAAA„

7326,AA463610„20,425,CCGCTGGAGAGAAAGTCAGG„

7327,AA463610„20,419,GAGAGAAAGTCAGGCTGTAG„

7328,AA463610„20,413,AAGTCAGGCTGTAGAGGGCT„ 7329,AA463610„20,407,GGCTGTAGAGGGCTTCTATA„

7330,AA463610„20,401,AGAGGGCTTCTATAATAATG„

7331,AA463610„20,395,CTTCTATAATAATGGTACCA„

7332,AA463610„20,389,TAATAATGGTACCACCAGGA„

7333,AA463610„20,383,TGGTACCACCAGGAGGTGGG„ 7334,AA463610„20,377,CACCAGGAGGTGGGAGAGTG„

7335,AA463610„20,371 ,GAGGTGGGAGAGTGGTTCAG„

7336,AA463610„20,365,GGAGAGTGGTTCAGTAAGGG„

7337,AA463610„20,359,TGGTTCAGTAAGGGAGGAGG„

7338,AA463610„20,353,AGTAAGGGAGGAGGAAGGTT„ 7339,AA463610„20,347,GGAGGAGGAAGGTTGCCAAA„

7340,AA463610„20,341,GGAAGGTTGCCAAAGAAATT„

7341,AA463610„20,335,TTGCCAAAGAAATTACTCAT„

7342,AA463610„20,329,AAGAAATTACTCATCTTTCA„

7343,AA463610„20,323,TTACTCATCTTTCAAAAATT„ 7344,AA463610„20,317,ATCTTTCAAAAATTCACTAG„

7345,AA463610„20,311 ,CAAAAATTCACTAGGTTACT„

7346,AA463610„20,305,TTCACTAGGTTACTGCCAGT„

7347,AA463610„20,299,AGGTTACTGCCAGTCAGCCA„

7348,AA463610„20,293,CTGCCAGTCAGCCAAACAAA„ 7349,AA463610„20,287,GTCAGCCAAACAAATCCTAG„

7350,AA463610„20,281 ,CAAACAAATCCTAGAAGAGA„

7351 ,AA463610„20,275,AATCCTAGAAGAGAACTGTT„

7352,AA463610„20,269,AGAAGAGAACTGTTGTGCCT„

7353,AA463610„20,263,GAACTGTTGTGCCTCCTAAA„ 7354.AA463610„20,257,TTGTGCCTCCTAAAAGAGAA„

7355.AA463610„20,251 ,CTCCTAAAAGAGAAAGGAAA„

7356,AA463610„20,245,AAAGAGAAAGGAAATTTCCT„

7357,AA463610„20,239,AAAGGAAATTTCCTCCTTTT„

7358,AA463610„20,233,AATTTCCTCCTTTTCCTTCC„ 7359.AA463610„20,227,CTCCTTTTCCTTCCTCTGGC„

7360.AA463610„20,221 ,TTCCTTCCTCTGGCACAGGA„

7361 ,AA463610„20,215,CCTCTGGCACAGGATGGGCT„

7362,AA463610„20,209,GCACAGGATGGGCTTCTAGC„

7363,AA463610„20,203,GATGGGCTTCTAGCAGATGG„ 7364,AA463610„20,197,CTTCTAGCAGATGGGATTTT„

7365.AA463610„20, 191 ,GCAGATGGGATTTTACATGT„

7366,AA463610„20, 185,GGGATTTTACATGTTATATT„

7367,AA463610„20,179,TTACATGTTATATTCTGAGT„

7368,AA463610„20,173,GTTATATTCTGAGTTTTAAA„ 7369.AA463610„20, 167,TTCTGAGTTTTAAACAAAAT„

7370.AA463610„20, 161 ,GTTTTAAACAAAATTTTGTG„

7371 ,AA463610„20, 155,AACAAAATTTTGTGCCTTAG„

7372.AA463610„20, 149,ATTTTGTGCCTTAGTCTCTA„

7373,AA463610„20,143,TGCCTTAGTCTCTATATCGC„ 7374.AA463610„20, 137,AGTCTCTATATCGCCCCCTC„

7375,AA463610„20,131,TATATCGCCCCCTCTCCTGA„

7376,AA463610„20,125,GCCCCCTCTCCTGACTTAAA„

7377,AA463610„20,119,TCTCCTGACTTAAATGGACA„

7378,AA463610„20,113,GACTTAAATGGACATATAGG„ 7379,AA463610„20,107,AATGGACATATAGGAGGTAT„

7380, AA463610„20, 101 ,CATATAGGAGGTATACTCTA„

7381,AA463610„20,95,GGAGGTATACTCTAAGCTCA„

7382,AA463610„20,89,ATACTCTAAGCTCAGTTATT„

7383,AA463610„20,83,TAAGCTCAGTTATTCAAGCA„ 7384,AA463610„20,77,CAGTTATTCAAGCATGTTTT„

7385,AA463610„20,71,TTCAAGCATGTTTTGATCAT„

7386,AA463610„20,65,CATGTTTTGATCATTAGAGC„

7387,AA463610„20,59,TTGATCATTAGAGCAAGATG„

7388,AA463610„20,53,ATTAGAGCAAGATGGGGTGT„ 7389,AA463610„20,47,GCAAGATGGGGTGTGGAAGG„

7390,AA463610„20,41,TGGGGTGTGGAAGGGGCAGC„

7391 ,AA463610„20,35,GTGGAAGGGGCAGCCGTGGT„

7392,AA463610„20,29,GGGGCAGCCGTGGTCTAAAA„

7393,AA463610„20,23,GCCGTGGTCTAAAAGGAACC„ 7394,AA463610„20,17,GTCTAAAAGGAACCAACAAC„

7395,AA463610„20,11,AAGGAACCAACAACAAATTT„

7396,AA463610„20,5,CCAACAACAAATTTTACCTA„

(GENBANK ACCESSION NO. R78585)

TTCTGGGTGTGCATCTGTTGAAATGCTCAAGACTTAATTATTTGCCTTTTGAAATCACTGTAAATGCCCCCATCCGGTTCCTCTTCTTC CCAGGTGTGCCAAGGAATTAATCTTGGTTTCACTACAATTAAAATTCACTCCTTTCCAATCATGTCATTGAAAGTGCCTTTAACGAA AGAAATGGTCACTGAATGGGAATTCTCTTAAGAAACCCTGAGATTAAAAAAAGACTATTTGGATAACTTATAGGAAAGCCTAGGAA CCTCCCAGTAGAGTGGGGATTTTTTTCTTCTTCCCTTTCTCTTTTGGACAATAGTTAAATTAGGCAGTATTAGTTATGAGTTTGGTTGC AGTGTTCTTATCTTGTGGGGCTGATTTCCAAAAACCACATGGCTGCTGGAATTTACCAGGGGTCCCTCATACCTCACANGGCAAACC ACTTACTACCAGGGCTTTTTCTGT (SEQ ID NO: 7397)

7398,R78585„20,443,ACAGAAAAAGCCCTGGTAGT„

7399,R78585„20,437,AAAGCCCTGGTAGTAAGTGG„

7400,R78585„20,431,CTGGTAGTAAGTGGTTTGCC„ 7401 ,R78585„20,425,GTAAGTGGTTTGCCNTGTGA„

7402,R78585„20,419,GGTTTGCCNTGTGAGGTATG„

7403,R78585„20,413,CCNTGTGAGGTATGAGGGAC„

7404,R78585„20,407,GAGGTATGAGGGACCCCTGG„

7405,R78585„20,401,TGAGGGACCCCTGGTAAATT„ 7406,R78585„20,395,ACCCCTGGTAAATTCCAGCA„

7407,R78585,,20,389,GGTAAATTCCAGCAGCCATG„

7408,R78585„20,383,TTCCAGCAGCCATGTGGTTT„

7409,R78585„20,377,CAGCCATGTGGTTTTTGGAA„

7410,R78585„20,371,TGTGGTTTTTGGAAATCAGC„ 74 I I ,R78585„20,365,TTTTGGAAATCAGCCCCACA„

7412,R78585„20,359,AAATCAGCCCCACAAGATAA„

7413,R78585„20,353,GCCCCACAAGATAAGAACAC„

7414,R78585„20,347,CAAGATAAGAACACTGCAAC„

7415,R78585„20,341,AAGAACACTGCAACCAAACT„ 7416,R78585„20,335,ACTGCAACCAAACTCATAAC„

7417,R78585„20,329,ACCAAACTCATAACTAATAC„

7418,R78585„20,323,CTCATAACTAATACTGCCTA„

7419,R78585„20,317,ACTAATACTGCCTAATTTAA„

7420,R78585„20,311,ACTGCCTAATTTAACTATTG„ 7421,R78585„20,30₅,TAATTTAACTATTGTCCAAA„

7422,R78585,,20,299,AACTATTGTCCAAAAGAGAA„

7423,R78585„20,293,TGTCCAAAAGAGAAAGGGAA„

7424,R78585„20,287,AAAGAGAAAGGGAAGAAGAA„

7425,R78585„20,281,AAAGGGAAGAAGAAAAAAAT„ 7426,R78585„20,275,AAGAAGAAAAAAATCCCCAC„

7427,R78585„20,269,AAAAAAATCCCCACTCTACT„

7428,R78585„20,263,ATCCCCACTCTACTGGGAGG„

7429,R78585„20,257,ACTCTACTGGGAGGTTCCTA„

7430,R7858₅„20,251,CTGGGAGGTTCCTAGGCTTT„ 7431,R78585„20,245,GGTTCCTAGGCTTTCCTATA„

7432,R78585„20,239,TAGGCTTTCCTATAAGTTAT„

7433,R78585„20,233,TTCCTATAAGTTATCCAAAT„

7434,R78585,,20,227,TAAGTTATCCAAATAGTCTT„

7435,R78585„20,221,ATCCAAATAGTCTTTTTTTA„ 7436,R78585„20,215,ATAGTCTTTTTTTAATCTCA„

7437,R78585„20,209,TTTTTTTAATCTCAGGGTTT„

7438,R78585„20,203,TAATCTCAGGGTTTCTTAAG„

7439,R78585„20,197,CAGGGTTTCTTAAGAGAATT„

7440,R78585„20,191,TTCTTAAGAGAATTCCCATT„ 7441,R78585„20,185,AGAGAATTCCCATTCAGTGA„

7442,R78585,,20,179,TTCCCATTCAGTGACCATTT„

7443,R78585„20,173,TTCAGTGACCATTTCTTTCG„

7444,R78585„20,167,GACCATTTCTTTCGTTAAAG„

7445,R78585„20,161,TTCTTTCGTTAAAGGCACTT„ 7446,R78585„20,155,CGTTAAAGGCACTTTCAATG„

7447,R78585„20,149,AGGCACTTTCAATGACATGA„

7448,R78585„20,143,TTTCAATGACATGATTGGAA„

7449,R78585„20,137,TGACATGATTGGAAAGGAGT„

7450,R78585„20,131,GATTGGAAAGGAGTGAATTT„ 7451₎R78585„20,125,AAAGGAGTGAATTTTAATTG„

7452,R78585„20,119,GTGAATTTTAATTGTAGTGA„

7453,R78585„20,113,TTTAATTGTAGTGAAACCAA„

7454,R78585„20,107,TGTAGTGAAACCAAGATTAA„

7455,R78585„20,101,GAAACCAAGATTAATTCCTT„ 7456,R78585„20,95,AAGATTAATTCCTTGGCACA„

7457,R78585„20,89,AATTCCTTGGCACACCTGGG„

7458,R78585„20,83,TTGGCACACCTGGGAAGAAG„

7459,R78585„20,77,CACCTGGGAAGAAGAGGAAC„

7460,R7858₅„20,71,GGAAGAAGAGGAACCGGATG„ 7461,R78585„20,65,AGAGGAACCGGATGGGGGCA„

7462₎R78585„20,59,ACCGGATGGGGGCATTTACA„

7463,R78585„20,53,TGGGGGCATTTACAGTGATT„

7464,R78585„20,47,CATTTACAGTGATTTCAAAA„

7465,R78585„20,41,CAGTGATTTCAAAAGGCAAA„ 7466,R78585„20,35,TTTCAAAAGGCAAATAATTA„ 7467,R78585„20,29,AAGGCAAATAATTAAGTCTT„

7468,R7858₅„20,23,AATAATTAAGTCTTGAGCAT„

7469,R78₅8₅„20,17,TAAGTCTTGAGCATTTCAAC„

7470,R78585,,20,11,TTGAGCATTTCAACAGATGC„

7471,R78585„20,5,ATTTCAACAGATGCACACCC„

(GENBANK ACCESSION NO. R33851)

CATTATATGACACCTTGCACTCTTACCGTCTTGACAGAAGCCAAGTAAGGAACTGAAGTTGTATCTGACTGTAGGGTGAATGTCTGA

GGCCTGCCTCCTAATAAAGACTCAAGGAGGAAGTCAATTGGGCATCTGCTAATAGAATGAACTCATGATGGGAAACTTCAGTTCAT

TTACTTTGTCCTGGAAAATTCCCGGGTTCTGTTCCATTTTGAGGCGAAATTGGGCCTTGGGGGAAAAACCACGTTCTTTCCTTTCCGA

TTTCTTTCATCCGGTCTTACGGNTATGGCAATTCCTCCCCCAANTATAGGATCTTTATTTCTGGCTCATTTTCCCCTA

(SEQ ID NO: 7472)

7473,R33851„20,320,TAGGGGAAAATGAGCCAGAA„

7474,R33851„20,314,AAAATGAGCCAGAAATAAAG„ 7475,R33851„20,308,AGCCAGAAATAAAGATCCTA„

7476.R33851 „20,302,AAATAAAGATCCTATANTTG„

7477,R33851 „20,296,AGATCCTATANTTGGGGGAG„

7478,R33851„20,290,TATANTTGGGGGAGGAATTG„

7479.R33851 „20,284,TGGGGGAGGAATTGCCATAN„ 7480,R33851„20,278,AGGAATTGCCATANCCGTAA„

7481 ,R33851 „20,272,TGCCATANCCGTAAGACCGG„

7482,R33851„20,266,ANCCGTAAGACCGGATGAAA„

7483,R33851„20,260,AAGACCGGATGAAAGAAATC„

7484,R33851„20,254,GGATGAAAGAAATCGGAAAG„ 7485,R33851„20,248,AAGAAATCGGAAAGGAAAGA„

7486.R33851 „20,242,TCGGAAAGGAAAGAACGTGG„

7487,R33851„20,236,AGGAAAGAACGTGGTTTTTC„

7488,R33851„20,230,GAACGTGGTTTTTCCCCCAA„

7489,R33851„20,224,GGTTTTTCCCCCAAGGCCCA„ 7490,R33851„20,218,TCCCCCAAGGCCCAATTTCG„

7491,R33851„20,212,AAGGCCCAATTTCGCCTCAA„

7492,R33851„20,206,CAATTTCGCCTCAAAATGGA„

7493,R33851„20,200,CGCCTCAAAATGGAACAGAA„

7494,R33851„20,194,AAAATGGAACAGAACCCGGG„ 7495,R33851„20,188,GAACAGAACCCGGGAATTTT„

7496,R33851 „20, 182,AACCCGGGAATTTTCCAGGA„

7497,R33851„20,176,GGAATTTTCCAGGACAAAGT„

7498,R33851,,20,170,TTCCAGGACAAAGTAAATGA„

7499,R33851 „20, 164,GACAAAGTAAATGAACTGAA„ 7500,R33851„20,158,GTAAATGAACTGAAGTTTCC„

7501 ,R33851 „20, 152,GAACTGAAGTTTCCCATCAT„

7502,R33851„20,146,AAGTTTCCCATCATGAGTTC„

7503,R33851„20,140,CCCATCATGAGTTCATTCTA„

7504,R33851„20,134,ATGAGTTCATTCTATTAGCA„ 7505,R33851„20,128,TCATTCTATTAGCAGATGCC„

7506,R33851„20,122,TATTAGCAGATGCCCAATTG„

7507,R33851 „20, 116,CAGATGCCCAATTGACTTCC„

7508,R33851„20,110,CCCAATTGACTTCCTCCTTG„

7509.R33851 „20, 104,TGACTTCCTCCTTGAGTCTT„ 7510,R33851„20,98,CCTCCTTGAGTCπTATTAG„

7511 ,R33851 „20,92,TGAGTCTTTATTAGGAGGCA„

7512,R33851„20,86,TTTATTAGGAGGCAGGCCTC„

7513,R33851 „20,80,AGGAGGCAGGCCTCAGACAT„

7514,R33851„20,74,CAGGCCTCAGACATTCACCC„ 7₅15,R33851„20,68,TCAGACATTCACCCTACAGT„

7516,R33851„20,62,ATTCACCCTACAGTCAGATA„

7517,R33851„20,56,CCTACAGTCAGATACAACTT„

7518,R33851 „20,50,GTCAGATACAACTTCAGTTC„

7519,R33851„20,44,TACAACTTCAGTTCCTTACT„ 7520,R33851„20,38,TTCAGTTCCTTACTTGGCTT„

7521,R33851„20,32,TCCTTACTTGGCTTCTGTCA„

7522,R33851„20,26,CTTGGCTTCTGTCAAGACGG„

7523,R33851„20,20,TTCTGTCAAGACGGTAAGAG„

7524,R33851„20,14,CAAGACGGTAAGAGTGCAAG„ 7525,R33851„20,8,GGTAAGAGTGCAAGGTGTCA„

7526,R33851„20,2,AGTGCAAGGTGTCATATAAT„

(GENBANK ACCESSION NO. R14663)

GATTTCAGACTGCAGAGGGGAAAGACTTCCATCTAGTCACAAAGACTCCTTCGTCCCCAGTTGCCGTCTAGGATTGGGCCTCCCATA

ATTGCTTTGCCAAAATACCAGAGCCTTCAAGTGCCAAACAGAGTATGTCCGATGGTATCTGGGTAAGGAAGGAAAGCAAAAGCAAG GGACCTTCATGCCCTTCTGATTCCCCTCCACCAAACCCCACTTCCCCTTCATAAGTTTGTTTAAACACTTATCTTCTGGGTTAGGAAT

GNCGGTTTAATTCCATATGCTCCAGGNTCTTTTGACTGGAAAAAAAAAAAGGAAGGAGGAGGAG

(SEQ LD NO: 7527)

7528,R14663„20,306,( 7529,R14663„20,300,C 7530,R14663„20,294,CCTTTTTTTTTTTCCAGTCA„

7531,R14663„20,288,TTTTTTTCCAGTCAAAAGAN„

7532,R14663„20,282,TCCAGTCAAAAGANCCTGGA„

7533,R14663„20,276,CAAAAGANCCTGGAGCATAT„ 7534,R14663„20,270,ANCCTGGAGCATATGGAATT„

7535,R14663„20,264,GAGCATATGGAATTAAACCG„

7536,R14663„20,258,ATGGAATTAAACCGNCATTC„

7537,R14663„20,252,TTAAACCGNCATTCCTAACC„

7538_;R14663„20,246,CGNCATTCCTAACCCAGAAG„ 7539_;R14663„20,240,TCCTAACCCAGAAGATAAGT„

7540,R14663„20,234,CCCAGAAGATAAGTGTTTAA„

7541,R14663„20,228,AGATAAGTGTTTAAACAAAC„

7542_JR14663„20,222,GTGTTTAAACAAACTTATGA„

7543,R14663„20,216,AAACAAACTTATGAAGGGGA„ 7544,R14663„20,210,ACTTATGAAGGGGAAGTGGG„

7545,R14663„20,204,GAAGGGGAAGTGGGGTTTGG„

7546,R14663„20,198,GAAGTGGGGTTTGGTGGAGG„

7547,R14663„20,192,GGGTTTGGTGGAGGGGAATC„

7548_>R14663„20,186,GGTGGAGGGGAATCAGAAGG„ 7549,R14663„20,180,GGGGAATCAGAAGGGCATGA„

7550_>R14663„20,174,TCAGAAGGGCATGAAGGTCC„

7551 ,R14663„20, 168,GGGCATGAAGGTCCCTTGCT„

7552,R14663„20,162,GAAGGTCCCTTGCTTTTGCT„

7553,R14663„20,156,CCCTTGCTTTTGCTTTCCTT„ 7554,R14663„20,150,CTTTTGCTTTCCTTCCTTAC„

7555,R14663„20,144,CTTTCCTTCCTTACCCAGAT„

7556,R14663„20,138,TTCCTTACCCAGATACCATC„

7557,R14663„20,132,ACCCAGATACCATCGGACAT„

7558,R14663„20,126,ATACCATCGGACATACTCTG„ 7559,R14663„20,120,TCGGACATACTCTGTTTGGC„

7560,R14663„20,114,ATACTCTGTTTGGCACTTGA„

7561 ,R14663„20, 108,TGTTTGGCACTTGAAGGCTC„

7562,R14663„20,102,GCACTTGAAGGCTCTGGTAT„

7563,R14663„20,96,GAAGGCTCTGGTATTTTGGC„ 7564,R14663„20,90,TCTGGTATTTTGGCAAAGCA„

7565,R14663„20,84,ATTTTGGCAAAGCAATTATG„

7566,R14663„20,78,GCAAAGCAATTATGGGAGGC„

7567,R14663„20,72,CAATTATGGGAGGCCCAATC„

7568,R14663„20,66,TGGGAGGCCCAATCCTAGAC„ 7569,R14663„20,60,GCCCAATCCTAGACGGCAAC„

7570,R14663„20,54,TCCTAGACGGCAACTGGGGA„

7571,R14663„20,48,ACGGCAACTGGGGACGAAGG„

7572,R14663„20,42,ACTGGGGACGAAGGAGTCTT„

7573,R14663„20,36,GACGAAGGAGTCTTTGTGAC„ 7574,R14663„20,30,GGAGTCTTTGTGACTAGATG„

7575,R14663„20,24,TTTGTGACTAGATGGAAGTC„

7576,R14663„20, 18,ACTAGATGGAAGTCTTTCCC„

7577,R14663„20,12,TGGAAGTCTTTCCCCTCTGC„

7578,R14663„20,6,TCTTTCCCCTCTGCAGTCTG„ (GENBANK ACCESSION NO. R33355)

TTTAAANNTAAAGATTCTTTTATTAATAAATTCTCCCTCCCCTCCAAACTCTCCCCAAAATAAATATCTCCTCCCCGCTTTGGGGAGA

TTGGGGGGGTCTGTATCTTAGGGCCAGCCCTCCTAGTGGGCCAGCCCCCTAGTGTTAAAAATAGGNCCCTAACCCCCCAGGGGTGA

CCCCCGTGGGNGGGAATTTCAGGGACATCTGAGTGAGTGGGGGCCTAGTGTCAAGTCTTGCCCCCCAAGTCAGCCTGGGCCCCCAG

GCTTCTTAGGGAAGGGANGGGCACCCCCCTNCCCTGTTGCAAATGCTTGCAGTTCCTTAGTCAGTGTCAGCTGTTT (SEQ ID NO: 7579)

7580,R33355„20,317,AAACAGCTGACACTGACTAA„

7581,R33355„20,311,CTGACACTGACTAAGGAACT„

7582,R33355„20,305,CTGACTAAGGAACTGCAAGC„ 7583,R33355„20,299,AAGGAACTGCAAGCATTTGC„

7584,R33355„20,293,CTGCAAGCATTTGCAACAGG„

7585,R33355„20,287,GCATTTGCAACAGGGNAGGG„

7586,R33355„20,281 ,GCAACAGGGNAGGGGGGTGC„

7587,R33355„20,275,GGGNAGGGGGGTGCCCNTCC„ 7588,R33355„20,269,GGGGGTGCCCNTCCCTTCCC„

7589,R33355„20,263,GCCCNTCCCTTCCCTAAGAA„

7590,R33355„20,2₅7,CCCTTCCCTAAGAAGCCTGG„

7591 ,R33355„20,251 ,CCTAAGAAGCCTGGGGGCCC„

7592,R33355„20,245,AAGCCTGGGGGCCCAGGCTG„ 7593,R33355„20,239,GGGGGCCCAGGCTGACTTGG„

7594,R33355„20,233,CCAGGCTGACTTGGGGGGCA„

7595,R33355„20,227,TGACTTGGGGGGCAAGACTT„

7596,R33355„20,221 ,GGGGGGCAAGACTTGACACT„

7597,R33355„20,215,CAAGACTTGACACTAGGCCC„ 7598,R33355„20,209,TTGACACTAGGCCCCCACTC„ 7599,R33355„20,203,CTAGGCCCCCACTCACTCAG„

7600,R33355„20,197,CCCCACTCACTCAGATGTCC„

7601 ,R33355„20, 191 ,TCACTCAGATGTCCCTGAAA„

7602,R33355„20, 185,AGATGTCCCTGAAATTCCCN„ 7603,R33355„20,179,CCCTGAAATTCCCNCCCACG„

7604,R33355„20,173,AATTCCCNCCCACGGGGGTC„

7605,R33355„20,167,CNCCCACGGGGGTCACCCCT„

7606,R33355„20, 161 ,CGGGGGTCACCCCTGGGGGG„

7607,R33355„20,155,TCACCCCTGGGGGGTTAGGG„ 7608,R33355„20,149,CTGGGGGGTTAGGGNCCTAT„

7609,R33355„20,143,GGTTAGGGNCCTATTTTTAA„

7610,R33355„20,137,GGNCCTATTTTTAACACTAG„

7611,R33355„20,131,ATTTTTAACACTAGGGGGCT„

7612,R33355„20,125,AACACTAGGGGGCTGGCCCA„ 7613,R33355„20,119,AGGGGGCTGGCCCACTAGGA„

7614,R33355„20,113,CTGGCCCACTAGGAGGGCTG„

761 ,R333₅₅„20,107,CACTAGGAGGGCTGGCCCTA„

7616,R333₅₅„20, 101 ,GAGGGCTGGCCCTAAGATAC„

7617,R333₅₅„20,95,TGGCCCTAAGATACAGACCC„ 7618,R33355„20,89,TAAGATACAGACCCCCCCAA„

7619,R33355„20,83,ACAGACCCCCCCAATCTCCC„

7620,R33355„20,77,CCCCCCAATCTCCCCAAAGC„

7621,R33355„20,71,AATCTCCCCAAAGCGGGGAG„

7622,R33355„20,65,CCCAAAGCGGGGAGGAGATA„ 7623,R3335₅„20,₅9,GCGGGGAGGAGATATTTATT„

7624,R33355„20,53,AGGAGATATTTATTTTGGGG„

7625,R33355„20,47,TATTTATTTTGGGGAGAGTT„

7626,R33355„20,41,TTTTGGGGAGAGTTTGGAGG„

7627,R33355„20,35,GGAGAGTTTGGAGGGGAGGG„ 7628,R33355„20,29,TTTGGAGGGGAGGGAGAATT„

7629,R33355„20,23,GGGGAGGGAGAATTTATTAA„

7630,R33355„20,17,GGAGAATTTATTAATAAAAG„

7631,R33355„20,11,TTTATTAATAAAAGAATCTT„

7632,R33355„20,5,AATAAAAGAATCTTTANNTT„ (GENBANK ACCESSION NO. T64626)

CTCAGGTGAGACCAGATTGTGTCATTTGGCTCCACCTTCATCTTGCAGANCAGCTGATCTCAGATTGCCAAGAAACTAGAAGCCACT

TGCACGGTGTGGCCAGAGCTCAGCTGGATGAGAGGCTGAGATGGGTGGCCAGCTTGTATACCAGTCCCTGAACTGAGCTGTTTACA

GGACTGGGGAGGCTCCACCCAGAAGGCTTTCATTTGTACTCTGCTGGGAGTGACTGGGAAAAACTCCTTCCCTGCTGCTGAGTGGAG

AGAGGCCTCATCCGGCTTTGACCCACCATCCGTTGCAGAAGCCTCCAGGGAGCAGCAATCCTAAGAGTTGGGAGGCAGCCAAGACC CCCTTTCCTTTCAAAACCTTCCCGGAAGTNGTTTT

(SEQ LD NO: 7633)

7634,T64626„20,362,AAAACNACTTCCGGGAAGGT„

7635,T64626„20,356,ACTTCCGGGAAGGTTTTGAA„ 7636,T64626„20,350,GGGAAGGTTTTGAAAGGAAA„

^' 7637,T64626„20,344,GTTTTGAAAGGAAAGGGGGT„

7638,T64626„20,338,AAAGGAAAGGGGGTCTTGGC„

7639,T64626„20,332,AAGGGGGTCTTGGCTGCCTC„

7640,T64626„20,326,GTCTTGGCTGCCTCCCAACT„ 7641,T64626„20,320,GCTGCCTCCCAACTCTTAGG„

7642,T64626„20,314,TCCCAACTCTTAGGATTGCT„

7643,T64626„20,308,CTCTTAGGATTGCTGCTCCC„

7644,T64626„20,302,GGATTGCTGCTCCCTGGAGG„

7645,T64626„20,296,CTGCTCCCTGGAGGCTTCTG„ 7646,T64626„20,290,CCTGGAGGCTTCTGCAACGG„

7647,T64626„20,284,GGCTTCTGCAACGGATGGTG„

7648,T64626„20,278,TGCAACGGATGGTGGGTCAA„

7649,T64626„20,272,GGATGGTGGGTCAAAGCCGG„

7650,T64626„20,266,TGGGTCAAAGCCGGATGAGG„ 7651 ,T64626„20,260,AAAGCCGGATGAGGCCTCTC„

7652,T64626„20,254,GGATGAGGCCTCTCTCCACT„

7653,T64626„20,248,GGCCTCTCTCCACTCAGCAG„

7654,T64626„20,242,TCTCCACTCAGCAGCAGGGA„

7655,T64626„20,236,CTCAGCAGCAGGGAAGGAGT„ 7656,T64626„20,230,AGCAGGGAAGGAGTTTTTCC„

7657,T64626„20,224,GAAGGAGTTTTTCCCAGTCA„

7658,T64626„20,218,GTTTTTCCCAGTCACTCCCA„

7659,T64626„20,212,CCCAGTCACTCCCAGCAGAG„

7660,T64626„20,206,CACTCCCAGCAGAGTACAAA„ 7661 ,T64626„20,200,CAGCAGAGTACAAATGAAAG„

7662,T64626„20, 194,AGTACAAATGAAAGCCTTCT„

7663,T64626„20, 188,AATGAAAGCCTTCTGGGTGG„

7664,T64626„20, 182,AGCCTTCTGGGTGGAGCCTC„

7665,T64626„20,176,CTGGGTGGAGCCTCCCCAGT„ 7666,T64626„20,170,GGAGCCTCCCCAGTCCTGTA„ 7667,T64626„20,164,TCCCCAGTCCTGTAAACAGC„

7668,T64626„20,158,GTCCTGTAAACAGCTCAGTT„

7669,T64626„20, 152,TAAACAGCTCAGTTCAGGGA„

7670,T64626„20, 146.GCTCAGTTCAGGGACTGGTA,, 7671 ,T64626„20, 140.TTCAGGGACTGGTATACAAG,,

7672,T64626„20,134,GACTGGTATACAAGCTGGCC„

7673,T64626„20,128,TATACAAGCTGGCCACCCAT„

7674,T64626„20,122,AGCTGGCCACCCATCTCAGC„

7675,T64626„20, 116,CCACCCATCTCAGCCTCTCA„ 7676,T64626„20, 110 ATCTCAGCCTCTCATCCAGC,,

7677,T64626„20,104,GCCTCTCATCCAGCTGAGCT„

7678,T64626„20,98,CATCCAGCTGAGCTCTGGCC„

7679,T64626„20,92,GCTGAGCTCTGGCCACACCG„

7680,T64626„20,86,CTCTGGCCACACCGTGCAAG„ 7681 ,T64626„20,80,CCACACCGTGCAAGTGGCTT„

7682,T64626„20,74,CGTGCAAGTGGCTTCTAGTT„

7683,T64626„20,68,AGTGGCTTCTAGTTTCTTGG„

7684,T64626„20,62,TTCTAGTTTCTTGGCAATCT„

768₅,T64626„20,56,TTTCTTGGCAATCTGAGATC„ 7686,T64626„20,50,GGCAATCTGAGATCAGCTGN„

7687,T64626„20,44,CTGAGATCAGCTGNTCTGCA„

7688,T64626„20,38,TCAGCTGNTCTGCAAGATGA„

7689,T64626„20,32,GNTCTGCAAGATGAAGGTGG„

7690,T64626„20,26,CAAGATGAAGGTGGAGCCAA„ 7691,T64626„20,20,GAAGGTGGAGCCAAATGACA„

7692,T64626„20,14,GGAGCCAAATGACACAATCT„

7693,T64626„20,8,AAATGACACAATCTGGTCTC„

7694,T64626„20,2,CACAATCTGGTCTCACCTGA„

(GENBANK ACCESSION NO. AA448261) TTTCCAGAAAAGGATATTTTTTTTATTCAAGTAACTGCAAATAGGAAACCAGAGAGGGAGCCCCAGGCTGGGACAAATCATGGCTA

CCCCTCCCCAACAGAACAGGGGGAGGAGGTGGCCCCTACACCCTTTATGGTCGATTCGGGCCCCCTTGCTCACTCTGCTGCAGCATC

CTAGGGGCAGGGCCAGCCTTCCCTGGGACTGGGGTAGTCGGTCACCCAGCCTGCCATGCCCCAGCCCCTCTTCCCCACAAAGAGTA

TCTTGGGGGAGGGGATCGTGGGCAGAACAGGAGGCAATGAGGATGAACATTTGGCGCTGGTAGCAGCAGCAATGACGGATTGTCG

AAGAATGGAACATTGAACA (SEQ ID NO: 7695)

7696.AA448261 „20,344,TGTTCAATGTTCCATTCTTC„ 7697,AA448261„20,338,ATGTTCCATTCTTCGACAAT„ 7698,AA448261 „20,332,CATTCTTCGACAATCCGTCA„ 7699,AA448261 „20,326,TCGACAATCCGTCATTGCTG„

7700.AA448261 „20,320,ATCCGTCATTGCTGCTGCTA„ 7701 ,AA448261 „20,314,CATTGCTGCTGCTACCAGCG„ 7702,AA448261„20,308,TGCTGCTACCAGCGCCAAAT„ 7703,AA448261„20,302,TACCAGCGCCAAATGTTCAT„ 7704,AA448261„20,296,CGCCAAATGTTCATCCTCAT„

7705,AA448261„20,290,ATGTTCATCCTCATTGCCTC„ 7706,AA448261„20,284,ATCCTCATTGCCTCCTGTTC„ 7707,AA448261„20,278,ATTGCCTCCTGTTCTGCCCA„ 7708,AA448261„20,272,TCCTGTTCTGCCCACGATCC„ 7709,AA448261„20,266,TCTGCCCACGATCCCCTCCC„

7710,AA448261 „20,260,CACGATCCCCTCCCCCAAGA„ 7711 ,AA448261 „20,254,CCCCTCCCCCAAGATACTCT„ 7712,AA448261„20,248,CCCCAAGATACTCTTTGTGG„ 7713,AA448261„20,242,GATACTCTTTGTGGGGAAGA„ 7714,AA448261„20,236,CTTTGTGGGGAAGAGGGGCT„

7715,AA448261„20,230,GGGGAAGAGGGGCTGGGGCA„ 7716,AA448261„20,224,GAGGGGCTGGGGCATGGCAG„ 7717, AA448261 ,,20,218 ,CTGGGGCATGGCAGGCTGGG„ 7718.AA448261 ,,20,212,CATGGCAGGCTGGGTGACCG„ 7719.AA448261 „20,206,AGGCTGGGTGACCGACTACC„

7720,AA448261 „20,200,GGTGACCGACTACCCCAGTC„ 7721,AA448261 „20, 194,CGACTACCCCAGTCCCAGGG„ 7722,AA448261„20,188,CCCCAGTCCCAGGGAAGGCT„ 7723,AA448261 „20, 182.TCCCAGGGAAGGCTGGCCCT,, 7724.AA448261 „20, 176,GGAAGGCTGGCCCTGCCCCT„

7725.AA448261 „20, 170,CTGGCCCTGCCCCTAGGATG„ 7726,AA448261 „20, 164,CTGCCCCTAGGATGCTGCAG„ 7727,AA448261„20,158,CTAGGATGCTGCAGCAGAGT„ 7728,AA448261 „20, 152 GCTGCAGCAGAGTGAGCAA,, 7729,AA448261„20,146,AGCAGAGTGAGCAAGGGGGC„

7730,AA448261„20,140,GTGAGCAAGGGGGCCCGAAT„ 7731,AA448261„20,134,AAGGGGGCCCGAATCGACCA„ 7732,AA448261„20,128,GCCCGAATCGACCATAAAGG„ 7733,AA448261„20,122,ATCGACCATAAAGGGTGTAG„ 7734,AA448261 „20, 116,CATAAAGGGTGTAGGGGCCA„ 7735,AA448261„20,110,GGGTGTAGGGGCCACCTCCT„

7736,AA448261„20,104,AGGGGCCACCTCCTCCCCCT„

7737,AA448261„20,98,CACCTCCTCCCCCTGTTCTG„

7738,AA448261„20,92,CTCCCCCTGTTCTGTTGGGG„ 7739,AA448261 „20,86,CTGTTCTGTTGGGGAGGGGT„

7740.AA448261 „20,80,TGTTGGGGAGGGGTAGCCAT„

7741,AA448261„20,74,GGAGGGGTAGCCATGATTTG„

7742.AA448261 „20,68,GTAGCCATGATTTGTCCCAG„

7743,AA448261„20,62,ATGATTTGTCCCAGCCTGGG„ 7744,AA448261„20,56,TGTCCCAGCCTGGGGCTCCC„

7745,AA448261 „20,50,AGCCTGGGGCTCCCTCTCTG„

7746,AA448261 „20,44,GGGCTCCCTCTCTGGTTTCC„

7747,AA448261„20,38,CCTCTCTGGTTTCCTATTTG„

7748,AA448261„20,32,TGGTTTCCTATTTGCAGTTA„ 7749.AA448261 „20,26,CCTATTTGCAGTTACTTGAA„

7750,AA448261„20,20,TGCAGTTACTTGAATAAAAA„

7751 ,AA448261 „20, 14,TACTTGAATAAAAAAAATAT„

7752,AA448261 „20,8,AATAAAAAAAATATCCTTTT„

7753,AA448261„20,2,AAAAATATCCTTTTCTGGAA„ (GENBANK ACCESSION NO. R44202)

AAGTCATGATTGAGTCTTAAAAAAGAACAATCCAGTGTTGCAGTTCAGAGAGGTTAGCATGTCAGGGCGCAGGCTCGGCGAGGNTG TGCTTTGCATTTAGGGACACAGCCCGGAGCCGCAGAAGGTCAGCAGGGAGCACGTCTGGGCACCTTCAGTACCAGGGCTGGGTGAG AGAGCCCGGA (SEQ ID NO: 7754)

7755,R44202„20,252,TCCGGGCTCTCTCACCCAGC„

7756,R44202„20,246,CTCTCTCACCCAGCCCTGGT„

7757,R44202„20,240,CACCCAGCCCTGGTACTGAA„ 7758,R44202„20,234,GCCCTGGTACTGAAGGTGCC„

7759,R44202„20,228,GTACTGAAGGTGCCCAGACG„

7760,R44202„20,222,AAGGTGCCCAGACGTGCTCC„

7761 ,R44202„20,216,CCCAGACGTGCTCCCTGCTG„

7762,R44202„20,210,CGTGCTCCCTGCTGACCTTC„ 7763,R44202„20,204,CCCTGCTGACCTTCTGCGGC„

7764,R44202„20, 198,TGACCTTCTGCGGCTCCGGG„

7765,R44202„20, 192,TCTGCGGCTCCGGGCTGTGT„

7766,R44202„20,186,GCTCCGGGCTGTGTCCCTAA„

7767,R44202„20, 180,GGCTGTGTCCCTAAATGCAA„ 7768,R44202„20,174,GTCCCTAAATGCAAAGCACA„

7769,R44202„20, 168,AAATGCAAAGCACANCCTCG„

7770,R44202„20,162,AAAGCACANCCTCGCCGAGC„

7771 ,R44202„20, 156,CANCCTCGCCGAGCCTGCGC„

7772,R44202„20, 150,CGCCGAGCCTGCGCCCTGAC„ 7773,R44202„20,144,GCCTGCGCCCTGACATGCTA„

7774,R44202„20, 138,GCCCTGACATGCTAACCTCT„

7775,R44202„20,132,ACATGCTAACCTCTCTGAAC„

7776,R44202„20,126,TAACCTCTCTGAACTGCAAC„

7777,R44202„20,120,CTCTGAACTGCAACACTGGA„ 7778,R44202„20,114,ACTGCAACACTGGATTGTTC„

778θ'R44202 2θ'l02^GATTGTTCTTTTTTAAGACτ",

7781 ,R44202„20,96,TCTTTTTTAAGACTCAATCA„

7782,R44202„20,90,TTAAGACTCAATCATGACTT„ 7783,R44202„20,84,CTCAATCATGACTTCTTTAC„

7784,R44202„20,78,CATGACTTCTTTACTAACAC„

7785,R44202,,20,72,TTCTTTACTAACACTGGCTA„

7786,R44202„20,66,ACTAACACTGGCTAGCTATA„

7787,R44202„20,60,ACTGGCTAGCTATATTATCT„ 7788,R44202„20,54,TAGCTATATTATCTTATATA„

7789,R44202„20,48,TATTATCTTATATACTAATA„

7790,R44202„20,42,CTTATATACTAATATCATGT„

7791,R44202„20,36,TACTAATATCATGTTTTAAA„

7792,R44202„20,30,TATCATGTTTTAAAAATATA„ 7793,R44202„20,24,GTTTTAAAAATATAAAATAG„

7794,R44202„20, 18,AAAATATAAAATAGAAATTA„

7795,R44202„20,12,TAAAATAGAAATTAAGAATC„

7796,R44202„20,6,AGAAATTAAGAATCTAAAAA„

(GENBANK ACCESSION NO. W81570) GCGACCGCTCGCGCCTCTCGANGGACAACTCGCACTTGCTCAACAAGGGCCTGCCGCTTGGGTCNGACCTCNGATCATGAACGGGC

ACCTGCANCCGCGGCCCCTGGTGGCATTGNTGGATGGCCGGGACTGCACAGTGGAGATGCCCATCCTGAAGGACGTGGCCACTGTG

GCTTCTGCGACGCGCAGTCCACGCAGGAGATCCATGAGAAGGTCCTGAACGAGGCTGTGGGGGCCCTGATGTACCACACCATCACT

CTCACCAGGGAGGACCTGGAGAAGTTCAAAGCCCTCCGCATCATCGTCCGGATTGGCAGTGGTTTTGACAACATCGACATCAAGTC

GGCCGGGGATTTTAGGCATTTGCCGTTCTGCAACGTGCCCGCGGCGTTCTGTTGGGAGGAGACGGCCGACTTCGA (SEQ LD NO: 7797) 7798,W81570„20,400,TCGAAGTCGGCCGTCTCCTC„

7799.W81570„20,394,TCGGCCGTCTCCTCCCAACA„

7800, W81570„20,388,GTCTCCTCCCAACAGAACGC„ 7801,W81570„20,382,TCCCAACAGAACGCCGCGGG„

7802.W81570„20,376,CAGAACGCCGCGGGCACGTT„

7803,W81570„20,370,GCCGCGGGCACGTTGCAGAA„

7804,W81570„20,364,GGCACGTTGCAGAACGGCAA„

7805,W81570„20,358,TTGCAGAACGGCAAATGCCT„ 7806, W81570„20,352,AACGGCAAATGCCTAAAATC„

7807,W81570„20,346,AAATGCCTAAAATCCCCGGC„

7808.W81570„20,340,CTAAAATCCCCGGCCGACTT„

7809,W81570„20,334,TCCCCGGCCGACTTGATGTC„

7810,W81570„20,328,GCCGACTTGATGTCGATGTT„ 7811 ,W81570„20,322,TTGATGTCGATGTTGTCAAA„

7812, W81570„20,316,TCGATGTTGTCAAAACCACT„

7813,W81₅70„20,310,TTGTCAAAACCACTGCCAAT„

7814,W81570„20,304,AAACCACTGCCAATCCGGAC„

7815,W81570„20,298,CTGCCAATCCGGACGATGAT„ 7816,W81570„20,292,ATCCGGACGATGATGCGGAG„

7817,W81570„20,286,ACGATGATGCGGAGGGCTTT„

7818,W81570„20,280, ATGCGGAGGGCTTTGAACTT,,

7819,W81570„20,274, AGGGCTTTGAACTTCTCCAG,,

7820.W81₅70„20,268,TTGAACTTCTCCAGGTCCTC„ 7821 ,W81570„20,262,TTCTCCAGGTCCTCCCTGGT„

7822, W81570„20,256,AGGTCCTCCCTGGTGAGAGT„

7823, 81570„20,250,TCCCTGGTGAGAGTGATGGT„

7824, W81570„20,244,GTGAGAGTGATGGTGTGGTA„

7825,W81570„20,238,GTGATGGTGTGGTACATCAG„ 7826.W81570„20,232,GTGTGGTACATCAGGGCCCC„

7827.W81570„20,226,TACATCAGGGCCCCCACAGC„

7828,W81570„20,220,AGGGCCCCCACAGCCTCGTT„

7829/W81570„20,214,CCCACAGCCTCGTTCAGGAC„

7830,W8157O„20,2O8,GCCTCGTTCAGGACCTTCTC„ 7831 ,W81570„20,202,TTCAGGACCTTCTCATGGAT„

7832,W81₅70„20,196,ACCTTCTCATGGATCTCCTG„

7833,W81₅70„20,190,TCATGGATCTCCTGCGTGGA„

7834,W81570„20, 184,ATCTCCTGCGTGGACTGCGC„

7835,W81570„20,178,TGCGTGGACTGCGCGTCGCA„ 7836,W81570„20,172,GACTGCGCGTCGCAGAAGCC„

7837,W81570„20,166,GCGTCGCAGAAGCCACAGTG„

7838, 81570„20, 160.CAGAAGCCACAGTGGCCACG,,

7839.W81570„20, 154,CCACAGTGGCCACGTCCTTC„

7840,W81570„20,148,TGGCCACGTCCTTCAGGATG„ 7841,W81570„20,142,CGTCCTTCAGGATGGGCATC„

7842,W81570„20,136,TCAGGATGGGCATCTCCACT„

7843,W81570„20,130,TGGGCATCTCCACTGTGCAG„

7844,W81570„20,124,TCTCCACTGTGCAGTCCCGG„

7845.W81570„20, 118,CTGTGCAGTCCCGGCCATCC„ 7846, 81570„20,112,AGTCCCGGCCATCCANCAAT„

7847,W81570„20,106,GGCCATCCANCAATGCCACC„

7848, 81570„20,100,CCANCAATGCCACCAGGGGC„

7849.W81570„20,94,ATGCCACCAGGGGCCGCGGN„

7850,W81570„20,88,CCAGGGGCCGCGGNTGCAGG„ 7851,W81570„20,82,GCCGCGGNTGCAGGTGCCCG„

7852,W81570„20,76,GNTGCAGGTGCCCGTTCATG„

7853,W81570„20,70,GGTGCCCGTTCATGATCNGA„

7854.W81570„20,64_>CGTTCATGATCNGAGGTCNG„

7855,W81570„20,58,TGATCNGAGGTCNGACCCAA„ 7856,W81570„20,52,GAGGTCNGACCCAAGCGGCA„

7857,W81570„20,46,NGACCCAAGCGGCAGGCCCT„

7858,W81570„20,40,AAGCGGCAGGCCCTTGTTGA„

7859.W81570„20,34,CAGGCCCTTGTTGAGCAAGT„

7860, W81570„20,28,CTTGTTGAGCAAGTGCGAGT„ ^' 7861,W81570„20,22,GAGCAAGTGCGAGTTGTCCN„

7862,W81₅70„20,16,GTGCGAGTTGTCCNTCGAGA„

7863,W81570„20,10,GTTGTCCNTCGAGAGGCGCG„

7864,W81570„20,4,CNTCGAGAGGCGCGAGCGGT„

(GENBANK ACCESSION NO. AA128561) ATTAGAAAAAAAAACTTCTTTAATGGGAAATTTTACGATTGAAATGATGTTTCATCTTATAGACCACAAACAAATGTTTTTAGACAT

TGAAAAGTGGTTAAAGACCAACTGCGCCCAGTCCCCCAAGTGCCATTTTCTGAGTGCAGAATGGAGGGTGACGTCTTGAGCTGATG

CTGTGTCCCCAGCATCAGGTTTTCTGTTTTCCCTCTTCTCCCTTTATTCCTTCCTTGTCCATTGCCCTCAACCTTCTTTTTCTGTTTGCT

CTGGCCTGGTTCAGTATAACATATCCATGAACTCTAGTATGGGCCTACGGACAATCATAGCTACAATCAGACTTTCTAAGCAAATGG

GGAATGTGGATNTACATATAACCATTAGAAACCCTATCATCACCTCCTAGAGGGGAAGTGAATTTCTTAAT (SEQ ID NO: 7865) 7866,AA128561„20,402,ATTAAGAAATTCACTTCCCC„

7867,AA128561„20,396,AAATTCACTTCCCCTCTAGG„

7868,AA128561„20,390,ACTTCCCCTCTAGGAGGTGA„ 7869,AA128561„20,384,CCTCTAGGAGGTGATGATAG„

7870,AA128561„20,378,GGAGGTGATGATAGGGTTTC„

7871,AA128561„20,372,GATGATAGGGTTTCTAATGG„

7872,AA128561„20,366,AGGGTTTCTAATGGTTATAT„

7873,AA128561„20,360,TCTAATGGTTATATGTANAT„ 7874,AA128561„20,354,GGTTATATGTANATCCACAT„

7875,AA128561„20,348,ATGTANATCCACATTCCCCA„

7876,AA128561„20,342,ATCCACATTCCCCATTTGCT„

7877,AA128₅61„20,336,ATTCCCCATTTGCTTAGAAA„

7878,AA128561„20,330,CATTTGCTTAGAAAGTCTGA„ 7879,AA128561„20,324,CTTAGAAAGTCTGATTGTAG„

7880,AA128561„20,318,AAGTCTGATTGTAGCTATGA„

7881,AA128561„20,312,GATTGTAGCTATGATTGTCC„

7882,AA128561„20,306,AGCTATGATTGTCCGTAGGC„

7883,AA12856I„20,300,GATTGTCCGTAGGCCCATAC„ 7884,AA128561„20,294,CCGTAGGCCCATACTAGAGT„

7885,AA128561„20,288,GCCCATACTAGAGTTCATGG„

7886,AA128561„20,282,ACTAGAGTTCATGGATATGT„

7887,AA128561„20,276,GTTCATGGATATGTTATACT„

7888,AA128561„20,270,GGATATGTTATACTGAACCA„ 7889,AA128561„20,264,GTTATACTGAACCAGGCCAG„

7890,AA128561„20,258,CTGAACCAGGCCAGAGCAAA„

7891,AA128561„20,252,CAGGCCAGAGCAAACAGAAA„

7892,AA128561„20,246,AGAGCAAACAGAAAAAGAAG„

7893,AA 128561 „20,240,AACAGAAAAAGAAGGTTGAG„ 7894,AA128561„20,234,AAAAGAAGGTTGAGGGCAAT„

7895,AA128561„20,228,AGGTTGAGGGCAATGGACAA„

7896,AA128561„20,222,AGGGCAATGGACAAGGAAGG„

7897,AA128561„20,216,ATGGACAAGGAAGGAATAAA„

7898.AA128561 ,,20,210,AAGGAAGGAATAAAGGGAGA„ 7899,AA 128561 „20,204,GGAATAAAGGGAGAAGAGGG„

7900,AA128561„20,198,AAGGGAGAAGAGGGAAAACA„

7901,AA128561„20,192,GAAGAGGGAAAACAGAAAAC„

7902,AAI28561„20,186,GGAAAACAGAAAACCTGATG„

7903,AA128561„20,180,CAGAAAACCTGATGCTGGGG„ 7904,AA128561„20,174,ACCTGATGCTGGGGACACAG„

7905,AA128561„20,168,TGCTGGGGACACAGCATCAG„

7906,AA128561„20,162,GGACACAGCATCAGCTCAAG„

7907.AA128561 „20, 156,AGCATCAGCTCAAGACGTCA„

7908,AA128561„20,150,AGCTCAAGACGTCACCCTCC„ 7909,AA128561„20,144,AGACGTCACCCTCCATTCTG„

7910,AA128561„20,138,CACCCTCCATTCTGCACTCA„

7911.AA128561 „20, 132,CCATTCTGCACTCAGAAAAT„

7912,AA128561„20,126,TGCACTCAGAAAATGGCACT„

7913,AA128561„20,120,CAGAAAATGGCACTTGGGGG„ 7914,AA128561„20,114,ATGGCACTTGGGGGACTGGG„

7915,AA128561„20,108,CTTGGGGGACTGGGCGCAGT„

7916,AA128561„20,102,GGACTGGGCGCAGTTGGTCT„

7917,AA128561„20,96,GGCGCAGTTGGTCTTTAACC„

7918,AA128561 „20,90,GTTGGTCTTTAACCACTTTT„ 7919,AA128561„20,84,CTTTAACCACTTTTCAATGT„

7920,AA128561„20,78,CCACTTTTCAATGTCTAAAA„

7921 ,AA128561 „20,72,TTCAATGTCTAAAAACATTT„

7922,AA128561„20,66,GTCTAAAAACATTTGTTTGT„

7923,AA128561„20,60,AAACATTTGTTTGTGGTCTA„ 7924,AA128561„20,54,TTGTTTGTGGTCTATAAGAT„

7925.AA128561 „20,48,GTGGTCTATAAGATGAAACA„

7926,AA128561„20,42,TATAAGATGAAACATCATTT„

7927,AA128561„20,36,ATGAAACATCATTTCAATCG„

7928,AA128561„20,30,CATCATTTCAATCGTAAAAT„ 7929,AA128561„20,24,TTCAATCGTAAAATTTCCCA„

7930,AA128561„20,18,CGTAAAATTTCCCATTAAAG„

7931,AA128561„20,12,ATTTCCCATTAAAGAAGTTT„

7932.AA128561 „20,6,CATTAAAGAAGTTTTTTTTT„

(GENBANK ACCESSION NO. N58473) CTGGGTATATTAAGACATTAATTATACTCTGGATGAAAATAAGGAATGTAGAAAAAAATGTGCCAAATATTACTCACTGCATGTGA

ACACGGATAATTAACAGACAATCCAGACAATATATCTGCTCATAGTCAATATTTTTATCGTATTTTTTTTTGACTGGGAAATGTACAC

ACTTTAGTTTCTCTGGTTCTCTGAATAACTGCCATCTATTTCTAAGCAACAGGAAAAGAATCTATATGAAACTTCTCGAAAAGTACTT

TCTGGCCAGGCGTGGTTGTTCACACCTGTAATTTCAGCATGTTGGGAGGCTGAGGCAGGTGGATTACTTGAGGCCAGGAGTTCAAGA

CCAGCCTGGCCAACATGGCGAAACCCCGTCTCTACTAAACATACAAAAAATCAGTTGGGCATGGTGGCGTGTGCTGTAGTCCCAGC TACTTGGGAGGCTGAGGCACAAGAATTGCTTCAACCCAGGGGACAGAAAAGAAAAGTACATTCTTTGGACATAGCTTCATTGCAGA

AAAAGAAAAAAAATCNCATCAAAGCAATTCATCTCTAACTAAAATACTAGGCATGTTGGTCNCGTGCCGA

(SEQ ID NO: 7933) 7934,N58473„20,572,TCGGCACGNGACCAACATGC„

7935,N58473„20,566,CGNGACCAACATGCCTAGTA„ 7936,N58473,,20,560,CAACATGCCTAGTATTTTAG„ 7937,N58473„20,554,GCCTAGTATTTTAGTTAGAG„ 7938,N58473„20,548,TATTTTAGTTAGAGATGAAT„ 7939,N58473„20,542,AGTTAGAGATGAATTGCTTT„

7940,N58473„20,536,AGATGAATTGCTTTGATGNG„ 7941,N58473„20,530,ATTGCTTTGATGNGATTTTT„ 7942,N58473„20,524,TTGATGNGATTTTTTTTCTT„ 7944,N58473„2o'512,TTTTTCTTTTTCTGCAATGA",

7945,N58473„20,506,TTTTTCTGCAATGAAGCTAT„

7946,N58473„20,500,TGCAATGAAGCTATGTCCAA„

7947,N58473„20,494,GAAGCTATGTCCAAAGAATG„

7948,N58473„20,488,ATGTCCAAAGAATGTACTTT„ 7949,N58473„20,482,AAAGAATGTACTTTTCTTTT„

7950,N58473„20,476,TGTACTTTTCTTTTCTGTCC„

7951,N58473„20,470,TTTCTTTTCTGTCCCCTGGG„

7952,N58473„20,464,TTCTGTCCCCTGGGTTGAAG„

7953,N58473„20,458,CCCCTGGGTTGAAGCAATTC„ 7954,N58473„20,452,GGTTGAAGCAATTCTTGTGC„

7955,N58473„20,446,AGCAATTCTTGTGCCTCAGC„

7956,N58473„20,440,TCTTGTGCCTCAGCCTCCCA„

7957,N58473„20,434,GCCTCAGCCTCCCAAGTAGC„

7958,N58473„20,428,GCCTCCCAAGTAGCTGGGAC„ 7959,N58473„20,422,CAAGTAGCTGGGACTACAGC„

7960,N58473„20,416,GCTGGGACTACAGCACACGC„

7961,N5S473„20,410,ACTACAGCACACGCCACCAT„

7962,N58473„20,404,GCACACGCCACCATGCCCAA„

7963,N58473„20,398,GCCACCATGCCCAACTGATT„ 7964,N58473„20,392,ATGCCCAACTGATTTTTTGT„

7965,N₅8473„20,386,AACTGATTTTTTGTATGTTT„

7966,N₅8473„20,380,TTTTTTGTATGTTTAGTAGA„

7967,N58473„20,374,GTATGTTTAGTAGAGACGGG„

7968,N58473„20,368,TTAGTAGAGACGGGGTTTCG„ 7969,N58473„20,362,GAGACGGGGTTTCGCCATGT„

7970,N58473„20,356,GGGTTTCGCCATGTTGGCCA„

7971,N58473„20,350,CGCCATGTTGGCCAGGCTGG„

7972,N58473„20,344,GTTGGCCAGGCTGGTCTTGA„

7973,N58473„20,338,CAGGCTGGTCTTGAACTCCT„ 7974,N58473„20,332,GGTCTTGAACTCCTGGCCTC„

7975,N58473„20,326,GAACTCCTGGCCTCAAGTAA„

7976,N58473„20,320,CTGGCCTCAAGTAATCCACC„

7977,N58473„20,314,TCAAGTAATCCACCTGCCTC„

7978,N58473„20,308,AATCCACCTGCCTCAGCCTC„ 7979,N58473„20,302,CCTGCCTCAGCCTCCCAACA„

7980,N58473„20,296,TCAGCCTCCCAACATGCTGA„

7981,N58473„20,290,TCCCAACATGCTGAAATTAC„

7982,N₅8473„20,284,CATGCTGAAATTACAGGTGT„

7983,N₅8473„20,278,GAAATTACAGGTGTGAACAA„ 7984,N58473„20,272,ACAGGTGTGAACAACCACGC„

7985,N58473„20,266,GTGAACAACCACGCCTGGCC„

7986,N58473„20,260,AACCACGCCTGGCCAGAAAG„

7987,N58473„20,254,GCCTGGCCAGAAAGTACTTT„

7988,N58473„20,248,CCAGAAAGTACTTTTCGAGA„ 7989,N58473„20,242,AGTACTTTTCGAGAAGTTTC„

7990,N58473„20,236,TTTCGAGAAGTTTCATATAG„

7991,N58473„20,230,GAAGTTTCATATAGATTCTT„

7992,N58473„20,224,TCATATAGATTCTTTTCCTG„

7993,N58473„20,218,AGATTCTTTTCCTGTTGCTT„ 7994,N58473„20,212,TTTTCCTGTTGCTTAGAAAT„

7995,N58473„20,206,TGTTGCTTAGAAATAGATGG„

7996,N58473„20,200,TTAGAAATAGATGGCAGTTA„

7997,N58473„20,194,ATAGATGGCAGTTATTCAGA„

7998,N58473„20,188,GGCAGTTATTCAGAGAACCA„ 7999,N58473„20, 182 ATTCAGAGAACCAGAGAAA,,

8000,N58473„20,176,GAGAACCAGAGAAACTAAAG„

8001,N58473„20,170,CAGAGAAACTAAAGTGTGTA„

8002,N58473„20,164,AACTAAAGTGTGTACATTTC„

8003,N58473„20,158,AGTGTGTACATTTCCCAGTC„ 8004,N58473„20,152,TACATTTCCCAGTCAAAAAA„ 8005,N58473„20,146,TCCCAGTCAAAAAAAAATAC„

8006,N58473„20,140,TCAAAAAAAAATACGATAAA„

8007,N58473„20,134,AAAAATACGATAAAAATATT„

8008,N58473„20,128,ACGATAAAAATATTGACTAT„ 8009,N58473„20,122,AAAATATTGACTATGAGCAG„

8010,N58473 „20, 116,TTGACTATGAGCAGATATAT„

8011,N58473„20,110,ATGAGCAGATATATTGTCTG„

8012,N58473„20,104,AGATATATTGTCTGGATTGT„

8013,N58473„20,98,ATTGTCTGGATTGTCTGTTA„ 8014,N58473„20,92,TGGATTGTCTGTTAATTATC„

8015,N58473„20,86,GTCTGTTAATTATCCGTGTT„

8016,N₅8473„20,80,TAATTATCCGTGTTCACATG„

8017,N₅8473„20,74,TCCGTGTTCACATGCAGTGA„

8018,N₅8473„20,68,TTCACATGCAGTGAGTAATA„ 8019,N58473„20,62,TGCAGTGAGTAATATTTGGC„

8020,N58473„20,56,GAGTAATATTTGGCACATTT„

8021,N58473„20,50,TATTTGGCACATTTTTTTCT„

8022,N58473„20,44,GCACATTTTTTTCTACATTC„

8023,N58473„20,38,TTTTTTCTACATTCCTTATT„ 8024,N58473„20,32,CTACATTCCTTATTTTCATC„

8025,N58473„20,26,TCCTTATTTTCATCCAGAGT„

8026,N58473„20,20,TTTTCATCCAGAGTATAATT„

8027,N58473„20,14,TCCAGAGTATAATTAATGTC„

8028,N58473„20,8,GTATAATTAATGTCTTAATA„ 8029,N58473„20,2,TTAATGTCTTAATATACCCA„

(GENBANK ACCESSION NO. AA679352)

ATCTTCTAAAAGGTCAAAAGCAATCCTGCTGTTTCTCTCTGAAAGCTAAACTCCTTTAAATGAGAATACGAGAATACCCAGAATTTT ATTCCCAGCCTTTGTGTGGAAAAGGCAGTTTGCATTCTTAGGAAACATCTAACTGTTACCTAAACCATAAATATTTCTATCTACTCCA TTCAACCCAATTAAAGAAAACAAAATGATGAGAAAAATAGGAGCCGAACAGAAAGAAAATTCACATCATTTTCTACTATTACGAAC

ATTCAAATGGTGCTTCAAATTAAATAATTTTAATTATCATTCTAGCCAAGATCATACTAAGTAGGATCTCCTGACAGTCCCATATGGC AGGGATTTAACCTAAAACGTGGCACTGAATGCTTCGCCA (SEQ ID NO: 8030) 8031,AA679352„20,458,TGGCGAAGCATTCAGTGCCA„

8032,AA679352„20,452,AGCATTCAGTGCCACGTTTT„

8033,AA679352„20,446,CAGTGCCACGTTTTAGGTTA„

8034,AA679352„20,440,CACGTTTTAGGTTAAATCCC„

8035,AA679352„20,434,TTAGGTTAAATCCCTGCCAT„ 8036,AA679352„20,428,TAAATCCCTGCCATATGGGA„

8037,AA679352„20,422,CCTGCCATATGGGACTGTCA„

8038,AA679352„20,416,ATATGGGACTGTCAGGAGAT„

8039,AA679352„20,410,GACTGTCAGGAGATCCTACT„

8040,AA6793₅2„20,404,CAGGAGATCCTACTTAGTAT„ 8041,AA679352„20,398,ATCCTACTTAGTATGATCTT„

8042,AA679352„20,392,CTTAGTATGATCTTGGCTAG„

8043,AA679352„20,386,ATGATCTTGGCTAGAATGAT„

8044,AA679352„20,380,TTGGCTAGAATGATAATTAA„

8045,AA679352„20,374,AGAATGATAATTAAAATTAT„ 8046,AA6793₅2„20,368,ATAATTAAAATTATTTAATT„

8047,AA679352„20,362,AAAATTATTTAATTTGAAGC„

8048,AA679352„20,356,ATTTAATTTGAAGCACCATT„

8049,AA679352„20,350,TTTGAAGCACCATTTGAATG„

8050,AA679352„20,344,GCACCATTTGAATGTTCGTA„ 8051,AA679352„20,338,TTTGAATGTTCGTAATAGTA„

8052,AA679352„20,332,TGTTCGTAATAGTAGAAAAT„

8053,AA679352„20,326,TAATAGTAGAAAATGATGTG„

8054,AA679352„20,320,TAGAAAATGATGTGAATTTT„

8055,AA679352„20,314,ATGATGTGAATTTTCTTTCT„ 8056,AA679352„20,308,TGAATTTTCTTTCTGTTCGG„

8057,AA679352„20,302,TTCTTTCTGTTCGGCTCCTA„

8058,AA679352„20,296,CTGTTCGGCTCCTATTTTTC„

8059,AA679352„20,290,GGCTCCTATTTTTCTCATCA„

8060,AA679352,,20,284,TATTTTTCTCATCATTTTGT„ 8061,AA679352„20,278,TCTCATCATTTTGTTTTCTT„

8062,AA679352„20,272,CATTTTGTTTTCTTTAATTG„

8063,AA679352„20,266,GTTTTCTTTAATTGGGTTGA„

8064,AA679352„20,260,TTTAATTGGGTTGAATGGAG„

8065,AA679352„20,254,TGGGTTGAATGGAGTAGATA„ 8066,AA679352„20,248,GAATGGAGTAGATAGAAATA„

8067,AA679352„20,242,AGTAGATAGAAATATTTATG„

8068,AA679352„20,236,TAGAAATATTTATGGTTTAG„

8069,AA679352„20,230,TATTTATGGTTTAGGTAACA„

8070,AA679352„20,224,TGGTTTAGGTAACAGTTAGA„ 8071,AA679352„20,218,AGGTAACAGTTAGATGTTTC„ 8072,AA679352„20,212,CAGTTAGATGTTTCCTAAGA„

8073,AA679352„20,206,GATGTTTCCTAAGAATGCAA„

8074,AA679352„20,200,TCCTAAGAATGCAAACTGCC„

8075,AA679352„20, 194,GAATGCAAACTGCCTTTTCC„ 807₆,AA679352„20,188,AAACTGCCTTTTCCACACAA„

8077,AA679352„20, 182,CCTTTTCCACACAAAGGCTG„

8078,AA679352„20,176,CCACACAAAGGCTGGGAATA„

8079,AA679352„20,170,AAAGGCTGGGAATAAAATTC„

8080,AA679352„20, 164,TGGGAATAAAATTCTGGGTA„ 8081 ,AA679352„20, 158,TAAAATTCTGGGTATTCTCG„

8082,AA679352„20, 152,TCTGGGTATTCTCGTATTCT„

8083,AA679352„20,146,TATTCTCGTATTCTCATTTA„

8084,AA679352„20,140,CGTATTCTCATTTAAAGGAG„

8085,AA679352„20,134,CTCATTTAAAGGAGTTTAGC„ 8086,AA679352„20,128,TAAAGGAGTTTAGCTTTCAG„

8087,AA679352„20,122,AGTTTAGCTTTCAGAGAGAA„

8088,AA679352„20,116,GCTTTCAGAGAGAAACAGCA„

8089,AA679352„20,110,AGAGAGAAACAGCAGGATTG„

8090,AA679352„20,104,AAACAGCAGGATTGCTTTTG„ 8091,AA679352„20,98,CAGGATTGCTTTTGACCTTT„

8092,AA679352„20,92,TGCTTTTGACCTTTTAGAAG„

8093,AA679352„20,86,TGACCTTTTAGAAGATTGGT„

8094,AA679352„20,80,TTTAGAAGATTGGTCTCCAG„

8095,AA679352„20,74,AGATTGGTCTCCAGTAAAGG„ 8096,AA679352„20,68,GTCTCCAGTAAAGGTGGACA„

8097,AA679352„20,62,AGTAAAGGTGGACATTTTTG„

8098,AA679352„20,56,GGTGGACATTTTTGAGATTT„

8099,AA679352„20,50,CATTTTTGAGATTTTTATAA„

8100,AA679352„20,44,TGAGATTTTTATAATAAAGA„ 8101,AA679352„20,38,TTTTATAATAAAGAATTTAA„

8102,AA679352„20,32,AATAAAGAATTTAATTGCTC„

8103,AA679352„20,26,GAATTTAATTGCTCTGCATT„

8104,AA6793₅2„20,20,AATTGCTCTGCATTTGTCAA„

8105,AA679352„20,14,TCTGCATTTGTCAAGTAAAA„ 8106,AA679352„20,8,TTTGTCAAGTAAAAAAAAAA„

8107,AA679352„20,2,AAGTAAAAAAAAAAAAAAAA„

(GENBANK ACCESSION NO. N55459)

TCAGGTCTAAAGTGTTTAATTATCACTCACATATTTCACAGGAAAAGGAATGTAGCAAATGGGTCAAGGTGGTATAAAAAAAAAAT

CCAGGTTTGTACATGTCTCTCTGTTTACATCTGGGAGAAAGGTTGTCCTGGCATCAGTCGCAGCAGCTGCACTTCTCTTGACGCCCCT TTGCNAACACAGCCCTGGGCACACTTGCTACAGCCCACGGGCANGCAGGAGCAGCAGCTCTTCTTGCANGAGGGTG

(SEQ ID NO: 8108)

8109,N55459„20,231,CACCCTCNTGCAAGAAGAGC„

8110,N55459„20,225,CNTGCAAGAAGAGCTGCTGC„ 8111,N55459„20,219,AGAAGAGCTGCTGCTCCTGC„

8112,N55459„20,213,GCTGCTGCTCCTGCNTGCCC„

8113,N55459„20,207,GCTCCTGCNTGCCCGTGGGC„

8114,N55459„20,201 ,GCNTGCCCGTGGGCTGTAGC„

8115,N55459„20, 195,CCGTGGGCTGTAGCAAGTGT„ 8116,N55459„20,189,GCTGTAGCAAGTGTGCCCAG„

8117,N55459„20,183,GCAAGTGTGCCCAGGGCTGT„

8118,N55459„20,177,GTGCCCAGGGCTGTGTTNGC„

8119,N55459„20,171,AGGGCTGTGTTNGCAAAGGG„

8120,N55459„20, 165,GTGTTNGCAAAGGGGCGTCA„ 8121,N55459„20,159,GCAAAGGGGCGTCAAGAGAA„

8122,N55459„20,I53,GGGCGTCAAGAGAAGTGCAG„

8123,N55459„20,147,CAAGAGAAGTGCAGCTGCTG„

8124,N55459„20,141,AAGTGCAGCTGCTGCGACTG„

8125,N55459„20,135,AGCTGCTGCGACTGATGCCA„ 8126,N55459„20,129,TGCGACTGATGCCAGGACAA„

8127,N55459„20,123,TGATGCCAGGACAACCTTTC„

8128,N55459„20,117,CAGGACAACCTTTCTCCCAG„

8129,N55459„20,111,AACCTTTCTCCCAGATGTAA„

8130,N55459„20,105,TCTCCCAGATGTAAACAGAG„ 8131 ,N55459„20,99,AGATGTAAACAGAGAGACAT„

8132,N55459„20,93,AAACAGAGAGACATGTACAA„

8133,N55459„20,87,AGAGACATGTACAAACCTGG„

8134,N55459„20,81 ,ATGTACAAACCTGGATTTTT„

8135,N55459„20,75,AAACCTGGATTTTTTTTTTA„ 8136,N55459„20,69,GGATTTTTTTTTTATACCAC„

8137,N55459„20,63,TTTTTTTATACCACCTTGAC„

8138,N55459„20,57,TATACCACCTTGACCCATTT„

8139,N55459„20,₅1 ,ACCTTGACCCATTTGCTACA„

8140,N55459„20,45,ACCCATTTGCTACATTCCTT„ 8141,N55459„20,39,TTGCTACATTCCTTTTCCTG„ S142,N55459„20,33,CATTCCTTTTCCTGTGAAAT„

8143,N₅₅459„20,27,TTTTCCTGTGAAATATGTGA„

8144,N55459„20,21,TGTGAAATATGTGAGTGATA„

8145,N55459„20,15,ATATGTGAGTGATAATTAAA„ 8146,N55459„20,9,GAGTGATAATTAAACACTTT„

8147,N55459„20,3,TAATTAAACACTTTAGACCT„

(GENBANK ACCESSION NO. AA150500)

TTTGGCGTAGAGAAAATATAGAGCCACTTTACTATTAAAAATGTATTTTCCAAAAGCAAGGTAGTTGCTGTCCCAAAAAGCCGAAA

GCCTCTAGTCCCTGCGGAACGGGCTGGATGGGGCTTCAGTCTGACACAGCCAGGCGGGGCAGCCCTCGNCGNGCTCGGATTCTCTG GGAGATTTGATAGAGCTCCATCGTTGCCCTCGCATCTTCCACCGAGCTGTGTCCAAGCAGGCTGTTCTGGATGCTCTTGTGCAGGAG

GCGCTCACTCAGCACCCGCAGAGAACACGCCTGCAGTGGTCCAGCTTGGCCTCACGCCACAACAGCCTGTCAGTGGACGTGTCGTA

GATTGTGTAGCCGCTCATGTCCTCTTTCAGTGCCTGGAAGTCGTGCTTCAGGTCATGACCCACCACCAGCTTGCCTTTCAGGAGCTGC

AGGATCTCTAGCCTGGCCACGGCAAATGGTGTGGCCCCCACCATGTGCTGAGGGGTGACCCGCTGAACCAGGTTCTG

(SEQ ID NO: 8148)

8149,AA150500„20,491,CAGAACCTGGTTCAGCGGGT„

8150,AA150500„20,485,CTGGTTCAGCGGGTCACCCC„

8151 ,AA150500„20,479,CAGCGGGTCACCCCTCAGCA„

8152.AA150500„20,473,GTCACCCCTCAGCACATGGT„ 8153,AA150500„20,467,CCTCAGCACATGGTGGGGGC„

8154,AA150500„20,461 ,CACATGGTGGGGGCCACACC„

8155,AA150500„20,455,GTGGGGGCCACACCATTTGC„

8156,AA 150500„20,449,GCCACACCATTTGCCGTGGC„

8157,AA150500„20,443,CCATTTGCCGTGGCCAGGCT„ 8158,AA150500„20,437,GCCGTGGCCAGGCTAGAGAT„

8159,AA150500„20,431 ,GCCAGGCTAGAGATCCTGCA„

8160,AA150500„20,425,CTAGAGATCCTGCAGCTCCT„

8161 ,AA 150500„20,419,ATCCTGCAGCTCCTGAAAGG„

8162,AA150500„20,413,CAGCTCCTGAAAGGCAAGCT„ 8163,AA150500₎,20,407,CTGAAAGGCAAGCTGGTGGT„

8164.AA150500„20,401 ,GGCAAGCTGGTGGTGGGTCA„

8165,AA150500„20,395,CTGGTGGTGGGTCATGACCT„

8166,AA150500„20,389,GTGGGTCATGACCTGAAGCA„

8167,AA150500„20,383,CATGACCTGAAGCACGACTT„ 8168,AA150500„20,377,CTGAAGCACGACTTCCAGGC„

8169,AA1₅0₅00„20,371,CACGACTTCCAGGCACTGAA„

8170,AA150500,,20,365,TTCCAGGCACTGAAAGAGGA„

8171,AA150500„20,359,GCACTGAAAGAGGACATGAG„

8172,AA150500„20,353,AAAGAGGACATGAGCGGCTA„ 8173,AA150500„20,347,GACATGAGCGGCTACACAAT„

8174,AA150500„20,341,AGCGGCTACACAATCTACGA„

8175,AA150₅00„20,33₅,TACACAATCTACGACACGTC„

8176,AA1₅0₅00„20,329,ATCTACGACACGTCCACTGA„

8177,AA150500„20,323,GACACGTCCACTGACAGGCT„ 8178,AA150500„20,317,TCCACTGACAGGCTGTTGTG„

8179,AA150500„20,311,GACAGGCTGTTGTGGCGTGA„

8180,AA150500„20,305,CTGTTGTGGCGTGAGGCCAA„

8181 ,AA150500„20,299,TGGCGTGAGGCCAAGCTGGA„

8182,AA150500„20,293,GAGGCCAAGCTGGACCACTG„ 8183.AA150500„20,287,AAGCTGGACCACTGCAGGCG„

8184.AA150500„20,281 ,GACCACTGCAGGCGTGTTCT„

8185,AA150500„20,275,TGCAGGCGTGTTCTCTGCGG„

8186,AA150500„20,269,CGTGTTCTCTGCGGGTGCTG„

8187.AA150500„20,263,CTCTGCGGGTGCTGAGTGAG„ 8188,AA150500„20,257,GGGTGCTGAGTGAGCGCCTC„

8189.AA150500„20,251 ,TGAGTGAGCGCCTCCTGCAC„

8190.AA 150500„20,245,AGCGCCTCCTGCACAAGAGC„

8191 ,AA150₅00„20,239,TCCTGCACAAGAGCATCCAG„

8192,AA1₅0₅00„20,233,ACAAGAGCATCCAGAACAGC„ 8193,AA1₅0₅00„20,227,GCATCCAGAACAGCCTGCTT„

8194.AA150500„20,221 ,AGAACAGCCTGCTTGGACAC„

8195,AA150500„20,215,GCCTGCTTGGACACAGCTCG„

8196,AA150500„20,209,TTGGACACAGCTCGGTGGAA„

8197,AA150500„20,203,ACAGCTCGGTGGAAGATGCG„ 8198,AA150500„20, 197,CGGTGGAAGATGCGAGGGCA„

8199,AA150500„20, 191 ,AAGATGCGAGGGCAACGATG„

8200.AA 150500„20, 185,CGAGGGCAACGATGGAGCTC„

8201,AA150500„20,179,CAACGATGGAGCTCTATCAA„

8202,AA150500„20,173,TGGAGCTCTATCAAATCTCC„ 8203,AA150500„20,167,TCTATCAAATCTCCCAGAGA„

8204,AA150500„20, 161 ,AAATCTCCCAGAGAATCCGA„

8205.AA150500„20, 155,CCCAGAGAATCCGAGCNCGN„

8206,AA150500„20,149,GAATCCGAGCNCGNCGAGGG„

8207,AA150500„20,143,GAGCNCGNCGAGGGCTGCCC„ 8208.AA150500„20, 137,GNCGAGGGCTGCCCCGCCTG„ 8209.AA150500„20, 131 ,GGCTGCCCCGCCTGGCTGTG„

8210,AA150500„20,125,CCCGCCTGGCTGTGTCAGAC„

8211,AA150500„20,119,TGGCTGTGTCAGACTGAAGC„

8212,AA150500„20,113,TGTCAGACTGAAGCCCCATC„ 8213.AA150500„20, 107,ACTGAAGCCCCATCCAGCCC„

8214,AA1₅0₅00„20,101,GCCCCATCCAGCCCGTTCCG„

8215.AA150500„20,95,TCCAGCCCGTTCCGCAGGGA„

8216,AA150500„20,89,CCGTTCCGCAGGGACTAGAG„

8217,AA150500„20,83,CGCAGGGACTAGAGGCTTTC„ 8218,AA150500„20,77,GACTAGAGGCTTTCGGCTTT„

8219,AA150500„20,71,AGGCTTTCGGCTTTTTGGGA„

8220,AA150500„20,65,TCGGCTTTTTGGGACAGCAA„

8221,AA150500„20,59,TTTTGGGACAGCAACTACCT„

8222,AA150500„20,₅3,GACAGCAACTACCTTGCTTT„ 8223,AA150500„20,47,AACTACCTTGCTTTTGGAAA„

8224,AA150500„20,41,CTTGCTTTTGGAAAATACAT„

8225,AA150500„20,35,TTTGGAAAATACATTTTTAA„

8226,AA150500„20,29,AAATACATTTTTAATAGTAA„

8227,AA150500„20,23,ATTTTTAATAGTAAAGTGGC„ 8228,AA150500„20,17,AATAGTAAAGTGGCTCTATA„

8229,AA150500„20, 11 ,AAAGTGGCTCTATATTTTCT„

8230,AA150500„20,5,GCTCTATATTTTCTCTACGC„

(GENBANK ACCESSION NO. H16833)

TTTTTTTTTAGGGGGCTATAGAAGGGATTGTGACATTTATTGTTCTGAAAATGCCATCAAAGACAGTTGTAAAGNCTAGTCTCATAC ACACTTGGCAAGACATAGCCAAAAGAGGTAAATTTGAAATTAGAAAAAATATCAGCAGTTATTACCCAGAGCTTGAAATTCTGACC

TGTTACACAGTAGGATATTCAACCTCCATTTCAGCGTATTTAGGTACTTATTAGGTAGATTGCAAAATTACTAGAAAAAAAATTCCT

AGAGGACATCTTGAAAATGATAAAGTAGCAGGAAANTTACAAAGTTATAACTTNATTTACAAGNTCCCTA

(SEQ ID NO: 8231) 8232,H16833„20,311,TAGGGANCTTGTAAATNAAG„

8233,H16833„20,305,NCTTGTAAATNAAGTTATAA„

8234,H16833„20,299,AAATNAAGTTATAACTTTGT„

8235,H16833„20,293,AGTTATAACTTTGTAANTTT„

8236,H16833„20,287,AACTTTGTAANTTTCCTGCT„ 8237.H16833„20,281 ,GTAANTTTCCTGCTACTTTA„

8238,H16833„20,275,TTCCTGCTACTTTATCATTT„

8239,H16833„20,269,CTACTTTATCATTTTCAAGA„

8240,H16833„20,263,TATCATTTTCAAGATGTCCT„

8241,H16833„20,257,TTTCAAGATGTCCTCTAGGA„ 8242,H16833„20,251,GATGTCCTCTAGGAATTTTT„

8243,H16833„20,245,CTCTAGGAATTTTTTTTCTA„

8244,H16833„20,239,GAATTTTTTTTCTAGTAATT„

8245,H16833„20,233,TTTTTCTAGTAATTTTGCAA„

8246,H16833„20,227,TAGTAATTTTGCAATCTACC„ 8247.H16833„20,221 ,TTTTGCAATCTACCTAATAA„

8248,H16833„20,215,AATCTACCTAATAAGTACCT„

8249,H16833„20,209,CCTAATAAGTACCTAAATAC„

8250,H16833„20,203,AAGTACCTAAATACGCTGAA„

8251,H16833„20,197,CTAAATACGCTGAAATGGAG„ 8252,H 16833„20, 191 ,ACGCTGAAATGGAGGTTGAA„

8253,H16833„20,185,AAATGGAGGTTGAATATCCT„

8254,H16833„20,179,AGGTTGAATATCCTACTGTG„

8255,H16833„20,173,AATATCCTACTGTGTAACAG„

8256,H16833„20, 167,CTACTGTGTAACAGGTCAGA„ 8257,H16833„20, 161 ,TGTAACAGGTCAGAATTTCA„

8258,H16833„20,155,AGGTCAGAATTTCAAGCTCT„

8259,H16833„20,149,GAATTTCAAGCTCTGGGTAA„

8260,H16833„20,143,CAAGCTCTGGGTAATAACTG„

8261,H16833„20,137,CTGGGTAATAACTGCTGATA„ 8262,H16833,,20,131,AATAACTGCTGATATTTTTT„

8263,H16833„20,125,TGCTGATATTTTTTCTAATT„

8264,H16833„20,119,TATTTTTTCTAATTTCAAAT„

8265.H 16833„20, 113,TTCTAATTTCAAATTTACCT„

8266,H16833„20,107,TTTCAAATTTACCTCTTTTG„ 8267,H16833„20,101,ATTTACCTCTTTTGGCTATG„

8268,H16833„20,95,CTCTTTTGGCTATGTCTTGC„

8269,H16833„20,89,TGGCTATGTCTTGCCAAGTG„

8270,H16833„20,83,TGTCTTGCCAAGTGTGTATG„

8271 ,H 16833„20,77,GCCAAGTGTGTATGAGACTA„ 8272,H16833„20,71,TGTGTATGAGACTAGNCTTT„

8273,H16833„20,65,TGAGACTAGNCTTTACAACT„

8274,H16833„20,59,TAGNCTTTACAACTGTCTTT„

8275,H16833„20,53,TTACAACTGTCTTTGATGGC„

8276,H16833„20,47,CTGTCTTTGATGGCATTTTC„ 8277,H16833„20,41,TTGATGGCATTTTCAGAACA„ 8278,H16833„20,35,GCATTTTCAGAACAATAAAT„

8279,H16833„20,29,TCAGAACAATAAATGTCACA„

8280,H16833„20,23,CAATAAATGTCACAATCCCT„

8281,H16833„20,17,ATGTCACAATCCCTTCTATA„

8282,H16833„20,11,CAATCCCTTCTATAGCCCCC„

8283,H16833„20,5,CTTCTATAGCCCCCTAAAAA„

(GENBANK ACCESSION NO. AA644211)

TAGTACAAAAATAAACAGACATTTATTTCCAGACTTATCTTTTACATAAGTTAAATACACATTTGTCTGAGGCACTGAAACATTCGC TTTTATACAAGCATATTGACTATTTCTTTCTTAACCTTAAACATTCTAAACGTAAAATTGTAAAGAAGATTCTCCTGAGTTATCTTTA

ATGATATTTATTTCATTTTCTCCCTCTTCCCAAAAGAAAATTTTTTTCAATTATTTATATAAATACTATTATCTGTAATCAGCGTTTGA TTTAAAAATATTAAAACCCACAGTGCTTGA (SEQ ID NO: 8284) 8285,AA644211„20,362,TCAAGCACTGTGGGTTTTAA„

82S6,AA644211„20,356,ACTGTGGGTTTTAATATTTT„

8287.AA6442 \ 1 „20,350,GGTTTTAATATTTTTAAATC„

8288,AA644211„20,344,AATATTTTTAAATCAAACGC„

8289,AA644211„20,338,TTTAAATCAAACGCTGATTA„ 8290,AA644211„20,332,TCAAACGCTGATTACAGATA„

8291,AA644211„20,326,GCTGATTACAGATAATAGTA„

8292.AA644211 „20,320,TACAGATAATAGTATTTATA„

8293,AA644211„20,314,TAATAGTATTTATATAAATA„

8294.AA644211 „20,308,TATTTATATAAATAATTGAA„ 8295.AA644211 „20,302,TATAAATAATTGAAAAAAAT„

8296,AA644211 „20,296,TAATTGAAAAAAATTTTCTT„

8297,AA644211„20,290,AAAAAAATTTTCTTTTGGGA„

8298,AA644211„20,284,ATTTTCTTTTGGGAAGAGGG„

8299,AA644211„20,278,TTTTGGGAAGAGGGAGAAAA„ 8300.AA644211„20,272,GAAGAGGGAGAAAATGAAAT„

8301 ,AA644211 „20,266,GGAGAAAATGAAATAAATAT„

8302.AA644211 „20,260,AATGAAATAAATATCATTAA„

8303,AA644211„20,2₅4,ATAAATATCATTAAAGATAA„

8304,AA644211 „20,248,ATCATTAAAGATAACTCAGG„ 8305.AA644211„20,242,AAAGATAACTCAGGAGAATC„

8306,AA644211„20,236,AACTCAGGAGAATCTTCTTT„

8307,AA644211„20,230,GGAGAATCTTCTTTACAATT„

8308.AA644211 „20,224,TCTTCTTTACAATTTTACGT„

8309.AA644211 ,,20,218,TTACAATTTTACGTTTAGAA„ 8310,AA644211„20,212,TTTTACGTTTAGAATGTTTA„

8311 ,AA644211 „20,206,GTTTAGAATGTTTAAGGTTA„

8312.AA644211„20,200,AATGTTTAAGGTTAAGAAAG„

8313 , AA644211 „20, 194,TAAGGTTAAGAAAGAAATAG„

8314.AA644211 „20, 188,TAAGAAAGAAATAGTCAATA„ 8315.AA644211 „20, 182,AGAAATAGTCAATATGCTTG„

8316,AA644211„20,176,AGTCAATATGCTTGTATAAA„

8317,AA644211„20,170,TATGCTTGTATAAAACACTG„

8318.AA644211 „20, 164,TGTATAAAACACTGTTCACT„

8319.AA644211 „20, 158,AAACACTGTTCACTGTTTTT„ 8320.AA644211„20,152,TGTTCACTGTTTTTTTTAAA„

8321 ,AA644211 „20, 146,CTGTTTTTTTTAAAAAAAAA„

8322.AA644211 „20, 140,TTTTTAAAAAAAAAACTTGA„

8323,AA644211„20,134,AAAAAAAAACTTGATTTGTT„

8324,AA644211„20, 128,AAACTTGATTTGTTATTAAC„ 8325.AA644211„20,122,GATTTGTTATTAACATTGAT„

8326.AA644211„20,116,TTATTAACATTGATCTGCTG„

8327.AA644211„20,110,ACATTGATCTGCTGACAAAA„

8328.AA644211 „20, 104,ATCTGCTGACAAAACCTGGG„

8329.AA644211 „20,98,TGACAAAACCTGGGAATTTG„ 8330.AA644211„20,92,AACCTGGGAATTTGGGTTGT„

8331,AA644211„20,86,GGAATTTGGGTTGTGTATGC„

8332.AA644211 „20,80,TGGGTTGTGTATGCGAATGT„

8333.AA644211 „20,74,GTGTATGCGAATGTTTCAGT„

8334,AA644211 „20,68,GCGAATGTTTCAGTGCCTCA„ 8335.AA644211 „20,62,GTTTCAGTGCCTCAGACAAA„

8336,AA644211„20,56,GTGCCTCAGACAAATGTGTA„

8337,AA644211„20,₅0,CAGACAAATGTGTATTTAAC„

8338,AA644211„20,44,AATGTGTATTTAACTTATGT„

8339,AA644211„20,38,TATTTAACTTATGTAAAAGA„ 8340.AA644211 „20,32,ACTTATGTAAAAGATAAGTC„

8341 ,AA644211 „20,26,GTAAAAGATAAGTCTGGAAA„

8342,AA644211„20,20,GATAAGTCTGGAAATAAATG„

8343.AA644211„20,14,TCTGGAAATAAATGTCTGTT„

8344,AA644211 „20,8,AATAAATGTCTGTTTATTTT„ 8345.AA644211„20,2,TGTCTGTTTATTTTTGTACT„ (GENBANK ACCESSION NO. AA001432)

TTTTTTTTAAGGACTACACTGCATTTTTTAATTCCATAAATTATAATCCTTTAACATATATGAAAGTTTCATATTCTTAAAGTGCTTTA

AAATATATTTAATTTTTTTAACAAGTGGAAAAGAATGTTTCTTAAAAGACATTTAATTTTTTAGTGGAAATTAATATTACCAAAAACA

TTCTGTGCATAACAATTTGAATAACAATTTTTTTATCTTCAAGAAATGGGATTTTTATATAAAATACACATGTAGCACTGAATGCCAA AGTGATGGGTATCCATGGTCAGAATTCAAAATTAGATTCGCTATTAAACCTGTCTGGTTTGTGTCCTGAGTGAAGAATGATCTCGAG

CCGGGGAGGGAGGTGCATTGGGTAATCAGTGCTTTTGAAGGTGAATTTCCTTGCTGTGAAATAGGCTTGGGTTACNGGGTCAGGAC

AACCATTCAGACTGACAGGCCCCTGGACTTCCAAGGCTTCAGTGACAGGGACAGGGATGTGATTGNCATGAATATTCCTCAGACAG

CCAAAGAATGATTTCCNCACAGGGATCCNCAGTGTCGTCAANTGGCNGGAGCACCTCA

(SEQ ID NO: 8346)

8347,AA001432„20,563,TGAGGTGCTCCNGCCANTTG„

8348,AA001432„20,557,GCTCCNGCCANTTGACGACA„

8349.AA001432„20,551 ,GCCANTTGACGACACTGNGG„

8350,AA001432„20,545,TGACGACACTGNGGATCCCT„ 8351 ,AA001432„20,539,CACTGNGGATCCCTGTGNGG„

8352,AA001432„20,533,GGATCCCTGTGNGGAAATCA„

8353,AA001432„20,527,CTGTGNGGAAATCATTCTTT„

8354,AA001432„20,521,GGAAATCATTCTTTGGCTGT„

8355,AA001432„20,₅15,CATTCTTTGGCTGTCTGAGG„ 8356,AA001432„20,509,TTGGCTGTCTGAGGAATATT„

8357,AA001432„20,503,GTCTGAGGAATATTCATGNC„

8358,AA001432„20,497,GGAATATTCATGNCAATCAC„

8359,AA001432„20,491,TTCATGNCAATCACATCCCT„

8360,AA001432„20,485,NCAATCACATCCCTGTCCCT„ 8361,AA001432„20,479,ACATCCCTGTCCCTGTCACT„

8362,AA001432„20,473,CTGTCCCTGTCACTGAAGCC„

8363,AA001432„20,467,CTGTCACTGAAGCCTTGGAA„

8364,AA001432„20,461,CTGAAGCCTTGGAAGTCCAG„

8365,AA001432„20,455,CCTTGGAAGTCCAGGGGCCT„ 8366,AA001432„20,449,AAGTCCAGGGGCCTGTCAGT„

8367,AA001432„20,443,AGGGGCCTGTCAGTCTGAAT„

8368,AA001432„20,437,CTGTCAGTCTGAATGGTTGT„

8369,AA001432„20,431,GTCTGAATGGTTGTCCTGAC„

8370,AA001432„20,425,ATGGTTGTCCTGACCCNGTA„ 8371 ,AA001432„20,419,GTCCTGACCCNGTAACCCAA„

8372₎AA001432„20,413,ACCCNGTAACCCAAGCCTAT„

8373,AA001432„20,407,TAACCCAAGCCTATTTCACA„

8374,AA001432„20,401,AAGCCTATTTCACAGCAAGG„

8375,AA001432„20,395,ATTTCACAGCAAGGAAATTC„ 8376,AA001432„20,389,CAGCAAGGAAATTCACCTTC„

8377,AA001432„20,383,GGAAATTCACCTTCAAAAGC„

8378,AA001432„20,377,TCACCTTCAAAAGCACTGAT„

8379,AA001432„20,371 ,TCAAAAGCACTGATTACCCA„

8380,AA001432„20,365,GCACTGATTACCCAATGCAC„ 8381,AA001432„20,359,ATTACCCAATGCACCTCCCT„

8382,AA001432„20,353,CAATGCACCTCCCTCCCCGG„

8383,AA001432„20,347,ACCTCCCTCCCCGGCTCGAG„

8384,AA001432„20,341,CTCCCCGGCTCGAGATCATT„

8385,AA001432„20,335,GGCTCGAGATCATTCTTCAC„ 8386.AA001432„20,329,AGATCATTCTTCACTCAGGA„

8387,AA001432„20,323,TTCTTCACTCAGGACACAAA„

8388,AA001432„20,317,ACTCAGGACACAAACCAGAC„

8389,AA001432„20,311,GACACAAACCAGACAGGTTT„

8390,AA001432„20,305,AACCAGACAGGTTTAATAGC„ 8391,AA001432„20,299,ACAGGTTTAATAGCGAATCT„

8392₁AA001432„20,293,TTAATAGCGAATCTAATTTT„

8393₁AA001432„20,287,GCGAATCTAATTTTGAATTC„

8394,AA001432„20₎281,CTAATTTTGAATTCTGACCA„

8395,AA001432„20,275,TTGAATTCTGACCATGGATA„ 8396_>AA001432„20,269,TCTGACCATGGATACCCATC„

8397,AA001432„20,263,CATGGATACCCATCACTTTG„

8398,AA001432„20,257,TACCCATCACTTTGGCATTC„

8399,AA001432„20,251,TCACTTTGGCATTCAGTGCT„

8400,AA001432„20,245,TGGCATTCAGTGCTACATGT„ 8401,AA001432„20,239,TCAGTGCTACATGTGTATTT„

8402,AA001432„20,233,CTACATGTGTATTTTATATA„

8403,AA001432„20,227,GTGTATTTTATATAAAAATC„

S404,AA001432„20,221,TTTATATAAAAATCCCATTT„

8405,AA001432„20,215,TAAAAATCCCATTTCTTGAA„ 8406,AA001432„20,209,TCCCATTTCTTGAAGATAAA„

8407,AA001432„20,203,TTCTTGAAGATAAAAAAATT„ ,

8408,AA001432„20, 197, AAGATAAAAAAATTGTTATT,,

8409,AA001432„20,191,AAAAAATTGTTATTCAAATT„

8410,AA001432„20,185,TTGTTATTCAAATTGTTATG„ 8411,AA001432„20,179,TTCAAATTGTTATGCACAGA„ 8412,AA001432„20,173,TTGTTATGCACAGAATGTTT„

8413,AA001432„20,167,TGCACAGAATGTTTTTGGTA„

8414.AA001432„20, 161 ,GAATGTTTTTGGTAATATTA„

8415,AA001432„20,155,TTTTGGTAATATTAATTTCC„ 8416,AA001432„20,149,TAATATTAATTTCCACTAAA„

8417,AA001432„20,143,TAATTTCCACTAAAAAATTA„

8418,AA001432„20, 137,CCACTAAAAAATTAAATGTC„

8419,AA001432„20, 131 ,AAAAATTAAATGTCTTTTAA„

8420.AA001432„20, 125,TAAATGTCTTTTAAGAAACA„ 8421,AA001432„20,119,TCTTTTAAGAAACATTCTTT„

8422,AA001432„20,113,AAGAAACATTCTTTTCCACT„

8423,AA001432„20,107,CATTCTTTTCCACTTGTTAA„

8424.AA001432„20, 101 ,TTTCCACTTGTTAAAAAAAT„

8425,AA001432„20,95,CTTGTTAAAAAAATTAAATA„ 8426,AA001432„20,89,AAAAAAATTAAATATATTTT„

8427,AA001432„20,83,ATTAAATATATTTTAAAGCA„

8428.AA001432„20,77,TATATTTTAAAGCACTTTAA„

8429,AA001432„20,71 ,TTAAAGCACTTTAAGAATAT„

8430,AA001432„20,65,CACTTTAAGAATATGAAACT„ 8431,AA001432„20,59,AAGAATATGAAACTTTCATA„

8432,AA001432„20,53,ATGAAACTTTCATATATGTT„

8433,AA001432„20,47,CTTTCATATATGTTAAAGGA„

8434,AA001432„20,41,TATATGTTAAAGGATTATAA„

8435,AA00I432„20,35,TTAAAGGATTATAATTTATG„ 8436,AA001432„20,29,GATTATAATTTATGGAATTA„

8437,AA001432„20,23,AATTTATGGAATTAAAAAAT„

8438,AA001432„20,17,TGGAATTAAAAAATGCAGTG„

8439.AA001432„20, 11 ,TAAAAAATGCAGTGTAGTCC„

8440,AA001432„20,₅,ATGCAGTGTAGTCCTTAAAA„ (GENBANK ACCESSION NO. H87S36)

AGAAAAAAAAACTTCTTTAATGGGAAATTTTACGNTTGAAATGATGTTTCATCTTATNGNCCACAAACAAATGTTTTTNGACATTGA

AAAGNGGNTAAAGACCAACTGCGCCCAGTCCCCCAAGNGCCATTTTCTGNGTGCAGAATGGNGGGNGACGTCTTGAGCTGATGCTG

TGTCCCCAGCATCAGGGTTTTCTGTTTTCCCTCTTCTCCCTTTATTCCTTCCTTGTCCATTGCCCTCAACCTTCTTTTTCTGTTTGCTCT

GGCCTGGGGTCAGTATAACANATCCATGAACTCTAGNATGGGGNCTACGGGCAATCATAGNTACAATCAGGGCT (SEQ ID NO: 8441)

8442,H87536„20,318,AGCCCTGATTGTANCTATGA„

8443,H87536„20,312,GATTGTANCTATGATTGCCC„

8444,H87536„20,306,ANCTATGATTGCCCGTAGNC„ S445,H87536„20,300,GATTGCCCGTAGNCCCCATN„

8446,H87536„20,294,CCGTAGNCCCCATNCTAGAG„

8447,H87536„20,288,NCCCCATNCTAGAGTTCATG„

8448,H87536„20,282,TNCTAGAGTTCATGGATNTG„

8449,H87536„20,276,AGTTCATGGATNTGTTATAC„ 8450,H87536„20,270,TGGATNTGTTATACTGACCC„

8451,H87536„20,264,TGTTATACTGACCCCAGGCC„

8452,H87536„20,258,ACTGACCCCAGGCCAGAGCA„

8453,H87536„20,252,CCCAGGCCAGAGCAAACAGA„

8454,H87536„20,246,CCAGAGCAAACAGAAAAAGA„ 8455,H87536„20,240,CAAACAGAAAAAGAAGGTTG„

8456,H87536„20,234,GAAAAAGAAGGTTGAGGGCA„

8457,H87536„20,228,GAAGGTTGAGGGCAATGGAC„

8458,H87536„20,222,TGAGGGCAATGGACAAGGAA„

8459,H87536„20,216,CAATGGACAAGGAAGGAATA„ 8460,H87536„20,210,ACAAGGAAGGAATAAAGGGA„

8461 ,H87536„20,204, AAGGAATAAAGGGAGAAGAG,,

8462,H87536„20,198_>TAAAGGGAGAAGAGGGAAAA„

8463,H87536„20, 192,GAGAAGAGGGAAAACAGAAA„

8464,H87536„20, 186, AGGGAAAACAGAAAACCCTG,, 8465,H87536„20, 180, AACAGAAAACCCTGATGCTG,,

8466_JH87536„20,174,AAACCCTGATGCTGGGGACA„

8467,H87536„20,168,TGATGCTGGGGACACAGCAT„

8468,H87536„20,162,TGGGGACACAGCATCAGCTC„

8469,H87536„20,156,CACAGCATCAGCTCAAGACG„ 8470,H87536„20, 150, ATCAGCTCAAGACGTCNCCC,,

8471,H87536„20,144,TCAAGACGTCNCCCNCCATT„

8472,H87536„20,138,CGTCNCCCNCCATTCTGCAC„

8473,H87536„20,132,CCNCCATTCTGCACNCAGAA„

8474,H87536„20,126,TTCTGCACNCAGAAAATGGC„ 8475,H87536„20,120,ACNCAGAAAATGGCNCTTGG„

8476,H87536„20,114,AAAATGGCNCTTGGGGGACT„

8477,H87536„20,108,GCNCTTGGGGGACTGGGCGC„

8478,H87536„20,102,GGGGGACTGGGCGCAGTTGG„

8479,H87₅36„20,96,CTGGGCGCAGTTGGTCTTTA„ 8480,H87₅36„20,90,GCAGTTGGTCTTTANCCNCT„ 8481 ,H87536„20,84,GGTCTTTANCCNCTTTTCAA„

8482,H87536„20,78,TANCCNCTTTTCAATGTCNA„

8483,H87₅36„20,72,CTTTTCAATGTCNAAAAACA„

8484,H87₅36„20,66,AATGTCNAAAAACATTTGTT„ 8485,H87536„20,60,NAAAAACATTTGTTTGTGGN„

8486,H87536,,20,54,CATTTGTTTGTGGNCNATAA„

8487,H87536„20,48,TTTGTGGNCNATAAGATGAA„

8488,H87536„20,42,GNCNATAAGATGAAACATCA„

8489,H87536„20,36,AAGATGAAACATCATTTCAA„ 8490,H87536„20,30,AAACATCATTTCAANCGTAA„

8491,H87₅36„20,24,CATTTCAANCGTAAAATTTC„

8492,H87536„20,18,AANCGTAAAATTTCCCATTA,,

8493,H87536„20,12,AAAATTTCCCATTAAAGAAG„

8494,H87536„20,6,TCCCATTAAAGAAGTTTTTT„ (GENBANK ACCESSION NO. AA664179)

CCAATGAACTCTGAACTTTTTATTGGCCTCCTGCTCCCCAAAGGGTACCCTGCTTCTGCTGGCTTAATGCCTCAGAACTTTGGTGTCA

TTGGTCTCAGACACCACTTTGCCATCCACTATCCGGCGGGTGGTGGTCTTTTGGATGGTTTGCATGGAGTTGCTGCTGTCCAAGGCAT

CACCAAGATTAAAGTCCTCGCCATCTTCCAGCAGGCGGCGGTAGGTGGCGATCTCAGCCTCCAGCTTGACCTTGATGTTCAGCAGGG

CCTCATACTCCTGGGCCTGGCGCTGTCCCTCTGCCCGGGTCTGTGCCAGCTCTGACTCAAGGTGCAGCAGGATCCCGTTGAGCTGCT CCATCTGTAGGGCGTACGGGCCTCCACCTCCCTCAGGCTGTTCTCCAAGCTGGCCTTCAGATTTCTCATGGAGTCCAGGTCGATCTCC

AGGACTGGACTGTACGTCTCAGCTCTGTGAGCGTCGTCTCAGCAGCTCAACCTCAGCAGACTGTGTGGTGACACTGTGGTGCTCTCC

TCATCTGCTGAGACCAGTACTTGTCTAGCTCCTCTCGGGTCTTCCGGAGCAGCTCGTCATATTGGCCCAGATGNCTGCAATGATCTG

GNCGAGGTCTGANGATTTGNGGCATCTACACTCAGGTCAACC

(SEQ ID NO: 8495)

8496,AA664179„20,635,GGTTGACCTGAGTGTAGATG„

8497,AA664179„20,629,CCTGAGTGTAGATGCCNCAA„

8498,AA664179„20,623,TGTAGATGCCNCAAATCNTC„

8499,AA664179„20,617,TGCCNCAAATCNTCAGACCT„ 8500,AA664179„20,611,AAATCNTCAGACCTCGNCCA„

8501,AA664179„20,605,TCAGACCTCGNCCAGATCAT„

8502,AA664179„20,599,CTCGNCCAGATCATTGCAGN„

8503,AA664179„20,593,CAGATCATTGCAGNCATCTG„

8504,AA664179„20,587,ATTGCAGNCATCTGGGCCAA„ 8505,AA664179„20,581,GNCATCTGGGCCAATATGAC„

8506,AA664179„20,575,TGGGCCAATATGACGAGCTG„

8507,AA664179„20,569,AATATGACGAGCTGCTCCGG„

8508,AA664179„20,563,ACGAGCTGCTCCGGAAGACC„

8509,AA664179„20,557,TGCTCCGGAAGACCCGAGAG„ 8510,AA664179„20,551,GGAAGACCCGAGAGGAGCTA„

8511 ,AA664179„20,545,CCCGAGAGGAGCTAGACAAG„

8512,AA664179„20,539,AGGAGCTAGACAAGTACTGG„

8513,AA664179„20,533,TAGACAAGTACTGGTCTCAG„

8514,AA664179„20,527,AGTACTGGTCTCAGCAGATG„ 8515,AA664179„20,521 ,GGTCTCAGCAGATGAGGAGA„

8516,AA664179„20,515,AGCAGATGAGGAGAGCACCA„

8517,AA664179„20,509,TGAGGAGAGCACCACAGTGT„

8518,AA664179„20,503,GAGCACCACAGTGTCACCAC„

8519,AA664179„20,497,CACAGTGTCACCACACAGTC„ 8520,AA664179„20,491,GTCACCACACAGTCTGCTGA„

8521,AA664179„20,485,ACACAGTCTGCTGAGGTTGA„

8522,AA664179„20,479,TCTGCTGAGGTTGAGCTGCT„

8523,AA664179„20,473,GAGGTTGAGCTGCTGAGACG„

8524,AA664179„20,467,GAGCTGCTGAGACGACGCTC„ 8525,AA664179„20,461,CTGAGACGACGCTCACAGAG„

8526,AA664179„20,455,CGACGCTCACAGAGCTGAGA„

8527,AA664179„20,449,TCACAGAGCTGAGACGTACA„

8528,AA664179„20,443,AGCTGAGACGTACAGTCCAG„

8529,AA664179„20,437,GACGTACAGTCCAGTCCTGG„ 8530,AA664179„20,431,CAGTCCAGTCCTGGAGATCG„

8531,AA664179„20,425,AGTCCTGGAGATCGACCTGG„

8532,AA664179„20,419,GGAGATCGACCTGGACTCCA„

8533,AA664179„20,413,CGACCTGGACTCCATGAGAA„

8534,AA664179„20,407,GGACTCCATGAGAAATCTGA„ 8535,AA664179„20,401,CATGAGAAATCTGAAGGCCA„

8536,AA664179„20,395,AAATCTGAAGGCCAGCTTGG„

8537,AA664179„20,389,GAAGGCCAGCTTGGAGAACA„

8538,AA664179„20,383,CAGCTTGGAGAACAGCCTGA„

8539,AA664179„20,377,GGAGAACAGCCTGAGGGAGG„ 8540,AA664179„20,371,CAGCCTGAGGGAGGTGGAGG„

8541,AA664179„20,365,GAGGGAGGTGGAGGCCCGTA„

8542,AA664179„20,359,GGTGGAGGCCCGTACGCCCT„

8543,AA664179„20,353,GGCCCGTACGCCCTACAGAT„

8544,AA664179„20,347,TACGCCCTACAGATGGAGCA„ 8545,AA664179„20,341,CTACAGATGGAGCAGCTCAA„ 8546,AA664179„20,335,ATGGAGCAGCTCAACGGGAT„

8547,AA664179„20,329,CAGCTCAACGGGATCCTGCT„

8548,AA664179„20,323,AACGGGATCCTGCTGCACCT„

8549,AA664179„20,317,ATCCTGCTGCACCTTGAGTC„ 8550,AA664179„20,31 l.CTGCACCTTGAGTCAGAGCT,,

8551,AA664179„20,305,CTTGAGTCAGAGCTGGCACA„

8552,AA664179„20,299,TCAGAGCTGGCACAGACCCG„

8553,AA664179„20,293,CTGGCACAGACCCGGGCAGA„

8554,AA664179„20,287,CAGACCCGGGCAGAGGGACA„ 8555,AA664179„20,281,CGGGCAGAGGGACAGCGCCA„

8556,AA664179„20,275,GAGGGACAGCGCCAGGCCCA„

8557,AA664179„20,269,CAGCGCCAGGCCCAGGAGTA„

8558,AA664179„20,263,CAGGCCCAGGAGTATGAGGC„

8559,AA664179„20,257,CAGGAGTATGAGGCCCTGCT„ 8560,AA664179„20,251,TATGAGGCCCTGCTGAACAT„

8561,AA664179„20,245,GCCCTGCTGAACATCAAGGT„

8562,AA664179„20,239,CTGAACATCAAGGTCAAGCT„

8563,AA664179„20,233,ATCAAGGTCAAGCTGGAGGC„

8564,AA664179„20,227,GTCAAGCTGGAGGCTGAGAT„ 8565,AA664179„20,221,CTGGAGGCTGAGATCGCCAC„

8566,AA664179„20,215,GCTGAGATCGCCACCTACCG„

8567,AA664179„20,209,ATCGCCACCTACCGCCGCCT„

8568,AA664179„20,203,ACCTACCGCCGCCTGCTGGA„

8569,AA664179„20,197,CGCCGCCTGCTGGAAGATGG„ 8570,AA664179„20,191,CTGCTGGAAGATGGCGAGGA„

85 1 ,AA664179„20, 185,GAAGATGGCGAGGACTTTAA„

8572,AA664179„20,179,GGCGAGGACTTTAATCTTGG„

8573,AA664179„20,173,GACTTTAATCTTGGTGATGC„

8574,AA664179,,20,167,AATCTTGGTGATGCCTTGGA„ 8575,AA664179„20, 161 ,GGTGATGCCTTGGACAGCAG„

8576,AA664179„20,155,GCCTTGGACAGCAGCAACTC„

8577,AA664179„20,149,GACAGCAGCAACTCCATGCA„

8578,AA664179„20,143,AGCAACTCCATGCAAACCAT„

8579,AA664179„20,137,TCCATGCAAACCATCCAAAA„ 8580,AA664179„20, 131 ,CAAACCATCCAAAAGACCAC„

8581,AA664179„20,125,ATCCAAAAGACCACCACCCG„

8582,AA664179„20,119,AAGACCACCACCCGCCGGAT„

8583,AA664179„20,113,ACCACCCGCCGGATAGTGGA„

8584,AA664179„20,107,CGCCGGATAGTGGATGGCAA„ 8585,AA664179„20,101,ATAGTGGATGGCAAAGTGGT„

8₅86,AA664179„20,95,GATGGCAAAGTGGTGTCTGA„

8587,AA664179„20,89,AAAGTGGTGTCTGAGACCAA„

8588,AA664179„20,83,GTGTCTGAGACCAATGACAC„

8589,AA664179„20,77,GAGACCAATGACACCAAAGT„ 8590.AA664179„20,71 ,AATGACACCAAAGTTCTGAG„

8591,AA664179„20,65,ACCAAAGTTCTGAGGCATTA„

8592,AA664179„20,59,GTTCTGAGGCATTAAGCCAG„

8593,AA664179„20,53,AGGCATTAAGCCAGCAGAAG„

8594,AA664179„20,47,TAAGCCAGCAGAAGCAGGGT„ 8595,AA664179„20,41,AGCAGAAGCAGGGTACCCTT„

8596,AA664179„20,3₅,AGCAGGGTACCCTTTGGGGA„

8597,AA664179„20,29,GTACCCTTTGGGGAGCAGGA„

8598,AA664179„20,23,TTTGGGGAGCAGGAGGCCAA„

8599,AA664179„20,17,GAGCAGGAGGCCAATAAAAA„ 8600,AA664179„20, 11 ,GAGGCCAATAAAAAGTTCAG„

8601,AA664179„20,5,AATAAAAAGTTCAGAGTTCA„

(GENBANK ACCESSION NO. H86812)

ACGGCTTGGGCTGGTACCTCAGCCAGATGCCCTTCTCCTGGCCACACCAGCTCACAGTGGAGAAGACCCCCGCGTATTTCACGTCGC

CCAAAGTGCCTGAGCGAGTCTACAGCATGAACCCGTCCATCCGGCTGCTGCTCATCCTGCGAGACCCGTCGGAGCGCGTGCTATCTG ACTACACCCAAGTGTTCTACAACCACATGCAGAAGCACAAGCCCTACCCGTCCATCGAGGAGTTCCTGGGTGCGNGATGGCAGGCT

CAATGTGGACTACAAGGCCCTCAACCGCAGCCTNTTACCACGTGCAACATGCAGAACTG

(SEQ ID NO: 8602)

8603,H86812„20,300,CAGTTCTGCATGTTGCACGT„ 8604,H86812„20,294,TGCATGTTGCACGTGGTAAN„

8605,H86812„20,288,TTGCACGTGGTAANAGGCTG„

8606,H86812„20,282,GTGGTAANAGGCTGCGGTTG„

8607,H86812„20,276,ANAGGCTGCGGTTGAGGGCC„

8608,H86812„20,270,TGCGGTTGAGGGCCTTGTAG„ 8609,H86812„20,264,TGAGGGCCTTGTAGTCCACA„

8610,H86812„20,258,CCTTGTAGTCCACATTGAGC„

8611,H86812„20,252,AGTCCACATTGAGCCTGCCA„

8612,H86812„20,246,CATTGAGCCTGCCATCNCGC„

8613,H86812„20,240,GCCTGCCATCNCGCACCCAG„ 8614,H86812„20,234,CATCNCGCACCCAGGAACTC„ 8615,H86812 ,20,228,GCACCCAGGAACTCCTCGAT„

8616,H86812_: ,20,222,AGGAACTCCTCGATGGACGG„

8617,H86812. ,20,216,TCCTCGATGGACGGGTAGGG„

8618,H86812_: ,20,210,ATGGACGGGTAGGGCTTGTG„ 8619,H86812„20,204,GGGTAGGGCTTGTGCTTCTG„

8620,H86812„20,198,GGCTTGTGCTTCTGCATGTG„

8621 ,H86812„20,192,TGCTTCTGCATGTGGTTGTA„

8622,H86812„20,186,TGCATGTGGTTGTAGAACAC„

8623,H86812„20,180,TGGTTGTAGAACACTTGGGT„ 8624,H86812„20,174,TAGAACACTTGGGTGTAGTC„

8625,H86812„20,16S,ACTTGGGTGTAGTCAGATAG„

8626,H86812„20,162,GTGTAGTCAGATAGCACGCG„

8627,H86812„20, 156,TCAGATAGCACGCGCTCCGA„

8628,H86812„20,150,AGCACGCGCTCCGACGGGTC„ 8629,H86812„20, 144,CGCTCCGACGGGTCTCGCAG„

8630,H86812„20,138,GACGGGTCTCGCAGGATGAG„

8631,H86812„20,132,TCTCGCAGGATGAGCAGCAG„

8632,H86812„20,126,AGGATGAGCAGCAGCCGGAT„

8633,H86812„20,120,AGCAGCAGCCGGATGGACGG„ 8634,H86812„20,114,AGCCGGATGGACGGGTTCAT„

8635,H86812„20,108,ATGGACGGGTTCATGCTGTA„

8636,H86812„20,102,GGGTTCATGCTGTAGACTCG„

8637,H86812„20,96,ATGCTGTAGACTCGCTCAGG„

8638,H86812„20,90,TAGACTCGCTCAGGCACTTT„ 8639,H86812„20,84,CGCTCAGGCACTTTGGGCGA„

8640,H86812„20,78,GGCACTTTGGGCGACGTGAA„

8641 ,H86812„20,72,TTGGGCGACGTGAAATACGC„

8642,H86812„20,66,GACGTGAAATACGCGGGGGT„

8643,H86812„20,60,AAATACGCGGGGGTCTTCTC„ 8644,H86812„20,54,GCGGGGGTCTTCTCCACTGT„

8645,H86812„20,48,GTCTTCTCCACTGTGAGCTG„

8646,H86812„20,42,TCCACTGTGAGCTGGTGTGG„

8647,H86812„20,36,GTGAGCTGGTGTGGCCAGGA„

8648,H86812„20,30,TGGTGTGGCCAGGAGAAGGG„ 8649,H86812„20,24,GGCCAGGAGAAGGGCATCTG„

8650,H86812„20,18,GAGAAGGGCATCTGGCTGAG„

8651,H86812„20,12,GGCATCTGGCTGAGGTACCA„

8652,H86812„20,6,TGGCTGAGGTACCAGCCCAA„

(GENBANK ACCESSION NO. AA626698) TTTTTTTGGTTTTATACAGAACCTTTAATTGCAAACAACTTGGAAGCAGCCATCCCGGGGGTGGCAGGGGAGAACCCACCACACCCT

CCCCTCAGTATTCTTCGCCTTCTTCAGCCTCAGCTTCCACGGAATCCACGCCCACCTCTTCATAATCCTTCTCTAGAGCTGCCAGGTC

CTCGCGGGCCTCAGAGAACTCTCCCTCTTCCATGCCTTCGCCCACGTACCAGTGCACAAAGGCCCGCTTGGCATACATGAGATCGAA

CTTATGGTCCAGGCGGGCCCAGGCCTCCGCAATGGCCGTGGTGTTGCTCAGCATGCACACGGCCCGCTGCACCTTGGCCAGGTCTCC

CCCGGGGACCACTGTGGGGGGCTGGTAGTTAATGCCCACCTTAAATCCAGTCGGGCACCAATCCACAAACTGGATAGTGCGCTTGG TCTTGATGGTGGCGATGGCGCGTTGACGTCTTTGGGGACCACGTCCCCCTGGTACAACATGCAGCAGGCCATGTACTTGCCGTGGCG

AGGGTCACACTTGACCATCTGATTGGCTGGCTCGAAGCAGGCATTGGTGATCTCGGCCAAAGAAAGCTGCTCGTGGTAAGCCTTCTA

AGCTGAGATGATTGGGGCGTAAGTGTGCCATGGGGAAATTGGATTCCGGGGTAACGGAACGAAGGTTGGGTCCGGAAATTC

(SEQ ID NO: 8653)

8654,AA626698„20_: 671 ,GAATTTCCGGACCCAACCTT„ 8655,AA626698„20_; 665.CCGGACCCAACCTTCGTTCC,, 8656,AA626698„20_: ,659,CCAACCTTCGTTCCGTTACC„ 8657,AA626698„20_; ,653,TTCGTTCCGTTACCCCGGAA„ 8658,AA626698„20. ,647,CCGTTACCCCGGAATCCAAT„ 8659,AA626698„20_; ,641 ,CCCCGGAATCCAATTTCCCC„ 8660,AA626698„20_; 635,AATCCAATTTCCCCATGGCA„ 8661,AA626698„20_; 629,ATTTCCCCATGGCACACTTA„ 8662,AA626698„20. 623,CCATGGCACACTTACGCCCC„ 8663,AA626698„20_: 617,CACACTTACGCCCCAATCAT„ 8664,AA626698„20_: 611 ,TACGCCCCAATCATCTCAGC„ 8665,AA626698„20_: ,605,CCAATCATCTCAGCTTAGAA„ 8666,AA626698„20_: ,599,ATCTCAGCTTAGAAGGCTTA„ 8667,AA626698„20_: ,593,GCTTAGAAGGCTTACCACGA„ 8668,AA626698„20_: ,587,AAGGCTTACCACGAGCAGCT„ 8669,AA626698„20_: ,581,TACCACGAGCAGCTTTCTTT„ 8670,AA626698„20_: ,575,GAGCAGCTTTCTTTGGCCGA„ 8671,AA626698„20_: ,569,CTTTCTTTGGCCGAGATCAC„ 8672,AA626698„20_: ,563,TTGGCCGAGATCACCAATGC„ 8673,AA626698„20_: ,557,GAGATCACCAATGCCTGCTT„ 8674,AA626698„20_: ,551,ACCAATGCCTGCTTCGAGCC„ 8675,AA626698„20. ,545,GCCTGCTTCGAGCCAGCCAA„ 8676,AA626698„20_: ,539,TTCGAGCCAGCCAATCAGAT„ 8677,AA626698„20_: ,533,CCAGCCAATCAGATGGTCAA„ 8678,AA626698„20_: 527,AATCAGATGGTCAAGTGTGA„ 8679,AA626698„20_: ,521 ,ATGGTCAAGTGTGACCCTCG„ S680,AA626698 ,20,515,AAGTGTGACCCTCGCCACGG„ 8681,AA626698 ,20,509,GACCCTCGCCACGGCAAGTA„ 8682.AA626698 ,20,503,CGCCACGGCAAGTACATGGC„ 8683.AA626698 ,20,497,GGCAAGTACATGGCCTGCTG„ 8684,AA626698 ,20,491 ,TACATGGCCTGCTGCATGTT„ 8685,AA626698 ,20,485,GCCTGCTGCATGTTGTACCA„ 8686.AA626698_: ,20,479,TGCATGTTGTACCAGGGGGA„ 8687,AA626698_; ,20,473,TTGTACCAGGGGGACGTGGT„ 8688,AA626698_; ,20,467,CAGGGGGACGTGGTCCCCAA„ 8689,AA626698 ,20,461 ,GACGTGGTCCCCAAAGACGT„ 8690.AA626698 ,20,455,GTCCCCAAAGACGTCAACGC„ 8691.AA626698 ,20,449,AAAGACGTCAACGCGCCATC„ 8692,AA626698 ,20,443,GTCAACGCGCCATCGCCACC„ 8693,AA626698_; ,20,437,GCGCCATCGCCACCATCAAG„ 8694,AA626698_; ,20,431 ,TCGCCACCATCAAGACCAAG„ 8695,AA626698_; ,20,425,CCATCAAGACCAAGCGCACT„ 8696,AA626698_; ,20,419,AGACCAAGCGCACTATCCAG„ 8697,AA626698, ,20,413,AGCGCACTATCCAGTTTGTG„ 8698,AA626698 ,20,407,CTATCCAGTTTGTGGATTGG„ 8699,AA626698 ,20,401 ,AGTTTGTGGATTGGTGCCCG„ 8700,AA626698 ,20,395,TGGATTGGTGCCCGACTGGA„ 8701,AA626698_; ,20,389,GGTGCCCGACTGGATTTAAG„ 8702,AA626698_: ,20,383,CGACTGGATTTAAGGTGGGC„ 8703.AA626698_: ,20,377,GATTTAAGGTGGGCATTAAC„ 8704.AA626698_: ,20,371 ,AGGTGGGCATTAACTACCAG„ 8705.AA626698_: ,20,365,GCATTAACTACCAGCCCCCC„ 8706,AA626698_: ,20,359,ACTACCAGCCCCCCACAGTG„ S707,AA626698_: ,20,353,AGCCCCCCACAGTGGTCCCC„ 8708,AA626698 ,20,347,CCACAGTGGTCCCCGGGGGA„ 8709.AA626698 ,20,341 ,TGGTCCCCGGGGGAGACCTG„ 8710,AA626698. ,20,335,CCGGGGGAGACCTGGCCAAG„ 8711.AA626698 ,20,329,GAGACCTGGCCAAGGTGCAG„ 8712,AA626698_; ,20,323,TGGCCAAGGTGCAGCGGGCC„ 8713.AA626698_: ,20,317,AGGTGCAGCGGGCCGTGTGC„ 8714,AA626698_: ,20,311.AGCGGGCCGTGTGCATGCTG,, 8715,AA626698_: ,20,305,CCGTGTGCATGCTGAGCAAC„ 8716.AA626698_: ,20,299,GCATGCTGAGCAACACCACG„ 8717.AA626698 ,20,293,TGAGCAACACCACGGCCATT„ 8718.AA626698 ,20,287,ACACCACGGCCATTGCGGAG„ 8719,AA626698 ,20,281,CGGCCATTGCGGAGGCCTGG„ 8720,AA626698_; ,20,275,TTGCGGAGGCCTGGGCCCGC„ 8721,AA626698_; ,20,269,AGGCCTGGGCCCGCCTGGAC„ 8722,AA626698_; ,20,263,GGGCCCGCCTGGACCATAAG„ 8723,AA626698_; ,20,257,GCCTGGACCATAAGTTCGAT„ 8724,AA626698_: ,20,2₅1 ,ACCATAAGTTCGATCTCATG„ 8725,AA626698, ,20,245,AGTTCGATCTCATGTATGCC„ 8726,AA626698_; ,20,239,ATCTCATGTATGCCAAGCGG„ 8727.AA626698_: ,20,233,TGTATGCCAAGCGGGCCTTT„ 8728,AA626698_; ,20,227,CCAAGCGGGCCTTTGTGCAC„ 8729,AA626698_: ,20,221 ,GGGCCTTTGTGCACTGGTAC„ 8730.AA626698_: ,20,215,TTGTGCACTGGTACGTGGGC„ 8731.AA626698, ,20,209,ACTGGTACGTGGGCGAAGGC„ 8732,AA626698_; ,20,203,ACGTGGGCGAAGGCATGGAA„ 8733,AA626698_: ,20, 197,GCGAAGGCATGGAAGAGGGA„ 8734.AA626698_: ,20, 191 ,GCATGGAAGAGGGAGAGTTC„ 8735.AA626698_: ,20, 185,AAGAGGGAGAGTTCTCTGAG„ 8736,AA626698_: ,20,179,GAGAGTTCTCTGAGGCCCGC„ 8737,AA626698_; ,20,173,TCTCTGAGGCCCGCGAGGAC„ 8738,AA626698_: ,20, 167,AGGCCCGCGAGGACCTGGCA„ 8739,AA626698_; ,20, 161 ,GCGAGGACCTGGCAGCTCTA„ 8740,AA626698_; ,20, 15₅,ACCTGGCAGCTCTAGAGAAG„ 8741,AA626698_: ,20,149,CAGCTCTAGAGAAGGATTAT„ 8742,AA626698_: ,20,143,TAGAGAAGGATTATGAAGAG„ 8743.AA626698_: ,20, 137,AGGATTATGAAGAGGTGGGC„ 8744.AA62669S_: ,20,131 , ATGAAGAGGTGGGCGTGGAT,, 8745,AA626698_: ,20,125,AGGTGGGCGTGGATTCCGTG„ 8746,AA626698_; ,20,119,GCGTGGATTCCGTGGAAGCT„ 8747.AA626698_: ,20,113,ATTCCGTGGAAGCTGAGGCT„ 8748,AA626698_: ,20,107,TGGAAGCTGAGGCTGAAGAA„ 8749,AA626698_; ,20,101 ,CTGAGGCTGAAGAAGGCGAA„ 8750,AA626698 ,20,95,CTGAAGAAGGCGAAGAATAC„ 8751.AA626698 ,20,89,AAGGCGAAGAATACTGAGGG„ 8752.AA626698 ,20,83,AAGAATACTGAGGGGAGGGT„ 8753,AA626698 ,20,77,ACTGAGGGGAGGGTGTGGTG„ 8754.AA626698 ,20,71 ,GGGAGGGTGTGGTGGGTTCT„ 8755,AA626698„20,65,GTGTGGTGGGTTCTCCCCTG„

8756,AA626698„20,59,TGGGTTCTCCCCTGCCACCC„

8757,AA626698„20,53,CTCCCCTGCCACCCCCGGGA„

87₅8,AA626698„20,47,TGCCACCCCCGGGATGGCTG„ 8759,AA626698„20,41,CCCCGGGATGGCTGCTTCCA„

8760,AA626698„20,35,GATGGCTGCTTCCAAGTTGT„

8761,AA626698„20,29,TGCTTCCAAGTTGTTTGCAA„

8762,AA626698„20,23,CAAGTTGTTTGCAATTAAAG„

8763,AA626698„20,17,GTTTGCAATTAAAGGTTCTG„ 8764,AA626698„20, 11 ,AATTAAAGGTTCTGTATAAA„

8765,AA626698„20,5,AGGTTCTGTATAAAACCAAA„

(GENBANK ACCESSION NO. R37953)

TTTTTTTTTCCNTTTAAAGTCATCTCTATAGGAAGGTNCTGGGAGGGATCCCAGAGAAAGAAAGGGCCAAGACTCCATTAACTGCCC

TGGATGAAGGGACTGCTACAANAGCTAGTACCAGAGACTCTCCTATCTCACGGTTGAGGCAGACCCAGGNTAGAATAGAGAATAAA AGGAATGCTTATAGGAAACAATTTTGTATGGAATGCTAGATGGCCAAGCTCAGCCTTTNGTCCAGTGCAACCCTTGCCTCGCTTGTC

AACAGTGAAAAATTAGTTTNGTTAGAAGAACCATCTGGAAACACACCAGCTTCTGCTACCTTCATGCTCATTGTTAAAAAAAGATTA

ACCAGTGTGAACATTCTGATCTGTTAATTCAGGGGACTNTTTTCTTTCCAATGGACTTTTTTGTTGGGAG

(SEQ ID NO: 8766) ' 8767,R37953„20,398,CTCCCAACAAAAAAGTCCAT„

8768,R37953„20,392,ACAAAAAAGTCCATTGGAAA„

8769,R37953„20,386,AAGTCCATTGGAAAGAAAAN„

8770,R37953„20,380,ATTGGAAAGAAAANAGTCCC„

8771,R37953„20,374,AAGAAAANAGTCCCCTGAAT„ 8772,R37953„20,368,ANAGTCCCCTGAATTAACAG„

8773,R379₅3„20,362,CCCTGAATTAACAGATCAGA„

8774,R379₅3„20,3₅6,ATTAACAGATCAGAATGTTC„

877₅,R37953„20,350,AGATCAGAATGTTCACACTG„

8776,R37953„20,344,GAATGTTCACACTGGTTAAT„ 8777,R37953„20,338,TCACACTGGTTAATCTTTTT„

8778,R37953„20,332,TGGTTAATCTTTTTTTAACA„

8779,R37953„20,326,ATCTTTTTTTAACAATGAGC„

8780,R37953„20,320,TTTTAACAATGAGCATGAAG„

8781,R37953„20,314,CAATGAGCATGAAGGTAGCA„ 8782,R37953„20,308,GCATGAAGGTAGCAGAAGCT„

8783,R37953„20,302,AGGTAGCAGAAGCTGGTGTG„

8784,R37953„20,296,CAGAAGCTGGTGTGTTTCCA„

8785,R37953„20,290,CTGGTGTGTTTCCAGATGGT„

8786,R37953„20,284,TGTTTCCAGATGGTTCTTCT„ 8787,R37953„20,278,CAGATGGTTCTTCTAACNAA„

8788,R37953„20,272,GTTCTTCTAACNAAACTAAT„

8789,R37953„20,266,CTAACNAAACTAATTTTTCA„

8790,R37953„20,260,AAACTAATTTTTCACTGTTG„

8791 ,R37953„20,254,ATTTTTCACTGTTGACAAGC„ 8792,R37953„20,248,CACTGTTGACAAGCGAGGCA„

8793,R37953„20,242,TGACAAGCGAGGCAAGGGTT„

8794,R37953„20,236,GCGAGGCAAGGGTTGCACTG„

8795,R37953„20,230,CAAGGGTTGCACTGGACNAA„

8796,R37953„20,224,TTGCACTGGACNAAAGGCTG„ 8797,R37953„20,218,TGGACNAAAGGCTGAGCTTG„

8798,R37953„20,212,AAAGGCTGAGCTTGGCCATC„

8799,R37953„20,206,TGAGCTTGGCCATCTAGCAT„

8800,R37953„20,200,TGGCCATCTAGCATTCCATA„

8801 ,R37953„20, 194,TCTAGCATTCCATACAAAAT„ 8802,R37953„20,188,ATTCCATACAAAATTGTTTC„

8803,R37953„20,182,TACAAAATTGTTTCCTATAA„

8804,R37953„20,176,ATTGTTTCCTATAAGCATTC„

8805,R37953„20,170,TCCTATAAGCATTCCTTTTA„

8806,R37953„20,164,AAGCATTCCTTTTATTCTCT„ 8807,R37953„20,158,TCCTTTTATTCTCTATTCTA„

8808,R37953„20,152,TATTCTCTATTCTANCCTGG„

8809,R37953„20,146,CTATTCTANCCTGGGTCTGC„

8810,R37953„20,140,TANCCTGGGTCTGCCTCAAC„

8811,R37953„20,134,GGGTCTGCCTCAACCGTGAG„ 8812,R37953„20,128,GCCTCAACCGTGAGATAGGA„

8813,R37953„20,122,ACCGTGAGATAGGAGAGTCT„

8814,R37953„20, 116,AGATAGGAGAGTCTCTGGTA„

8815,R37953„20,110,GAGAGTCTCTGGTACTAGCT„

8816,R37953„20,104,CTCTGGTACTAGCTNTTGTA„ 8817,R37953„20,98,TACTAGCTNTTGTAGCAGTC„

8818,R37953„20,92,CTNTTGTAGCAGTCCCTTCA„

8819,R37953„20,86,TAGCAGTCCCTTCATCCAGG„

8820,R37953„20,80,TCCCTTCATCCAGGGCAGTT„

8821,R37953„20,74,CATCCAGGGCAGTTAATGGA„ 8822,R37953„20,68,GGGCAGTTAATGGAGTCTTG„ 8823,R37953„20,62,TTAATGGAGTCTTGGCCCTT„

8824,R37953„20,56,GAGTCTTGGCCCTTTCTTTC„

8825,R37953„20,₅0,TGGCCCTTTCTTTCTCTGGG„

8826,R37953„20,44,TTTCTTTCTCTGGGATCCCT„ 8827,R379₅3„20,38,TCTCTGGGATCCCTCCCAGN„

8828,R379₅3„20,32,GGATCCCTCCCAGNACCTTC„

8829,R37953„20,26,CTCCCAGNACCTTCCTATAG„

8830,R37953„20,20,GNACCTTCCTATAGAGATGA„

8831,R37953„20,14,TCCTATAGAGATGACTTTAA„ 8832,R37953„20,8,AGAGATGACTTTAAANGGAA„

8833,R37953„20,2,GACTTTAAANGGAAAAAAAA„

(GENBANK ACCESSION NO. AA069372)

GGACTCTGCACCAAGGGACTGCCCTGTCCAGTGTCGAGAACTTTACTGCTAGGATTTCCAATTGTTAATAACGCTATGTTAGCGCGC

TCGAGGAAGAAGGTAGGAATCCCGGCTCCTTTTCTCNTCTTAGGTGGTTCGGTGTTTTGTTCGCTCCTCCAGGCGCGGCCCCTCTCGA CCTCGCGCGCCCATNTTCGCCGCTGCGAATTCTCGGACAAAACTGTCAACAGCCCGGNCGCGCCTTTTNGCTCTNCGGGTCCCNCTA

ATTTATGCAAAGCCGACCTATGCTACAGCCCCCCAACCCCCGACCTTGGGGTAGGGAAGGAAGAGGGTGCCGGGGGAAGGGAATC

CGCNCTGTCCAGGCACTANAGGCTCCCTTGGACCGTTTTGGCAGATGAA

(SEQ ID NO: 8834) 8835,AA069372„20,377,TTCATCTGCCAAAACGGTCC„

8836,AA069372„20,371,TGCCAAAACGGTCCAAGGGA„

8837,AA069372„20,365,AACGGTCCAAGGGAGCCTNT„

8838,AA069372„20,359,CCAAGGGAGCCTNTAGTGCC„

8839,AA069372„20,353,GAGCCTNTAGTGCCTGGACA„ 8840,AA069372„20,347,NTAGTGCCTGGACAGNGCGG„

8841,AA069372„20,341,CCTGGACAGNGCGGATTCCC„

8842,AA069372„20,335,CAGNGCGGATTCCCTTCCCC„

8843,AA069372„20,329,GGATTCCCTTCCCCCGGCAC„

8844,AA069372„20,323,CCTTCCCCCGGCACCCTCTT„ 8845,AA069372„20,317,CCCGGCACCCTCTTCCTTCC„

8846,AA069372„20,311 ,ACCCTCTTCCTTCCCTACCC„

8847,AA069372„20,305,TTCCTTCCCTACCCCAAGGT„

8848,AA069372„20,299,CCCTACCCCAAGGTCGGGGG„

8849,AA069372„20,293,CCCAAGGTCGGGGGTTGGGG„ 8850,AA069372„20,287,GTCGGGGGTTGGGGGGCTGT„

8851 ,AA069372„20,281 ,GGTTGGGGGGCTGTAGCATA„

8852,AA069372„20,275,GGGGCTGTAGCATAGGTCGG„

8853,AA069372„20,269,GTAGCATAGGTCGGCTTTGC„

8854,AA069372„20,263,TAGGTCGGCTTTGCATAAAT„ 8855,AA069372,,20,257,GGCTTTGCATAAATTAGNGG„

8856,AA069372„20,251,GCATAAATTAGNGGGACCCG„

8857,AA069372„20,245,ATTAGNGGGACCCGNAGAGC„

8858,AA069372„20,239,GGGACCCGNAGAGCNAAAAG„

8859,AA069372„20,233,CGNAGAGCNAAAAGGCGCGN„ 8860,AA069372„20,227,GCNAAAAGGCGCGNCCGGGC„

8861,AA069372„20,221,AGGCGCGNCCGGGCTGTTGA„

8862,AA069372„20,215,GNCCGGGCTGTTGACAGTTT„

8863,AA069372„20,209,GCTGTTGACAGTTTTGTCCG„

8864,AA069372„20,203,GACAGTTTTGTCCGAGAATT_;, 8865,AA069372„20,197,TTTGTCCGAGAATTCGCAGC„

8866,AA069372„20, 191 ,CGAGAATTCGCAGCGGCGAA„

8867,AA069372„20,185,TTCGCAGCGGCGAANATGGG„

8868,AA069372„20,179,GCGGCGAANATGGGCGCGCG„

8869,AA069372„20,173,AANATGGGCGCGCGAGGTCG„ 8870,AA069372„20,167,GGCGCGCGAGGTCGAGAGGG„

8871 ,AA069372„20, 161 ,CGAGGTCGAGAGGGGCCGCG„

8872,AA069372„20,155,CGAGAGGGGCCGCGCCTGGA„

8873,AA069372„20,149,GGGCCGCGCCTGGAGGAGCG„

8874,AA069372„20,143,CGCCTGGAGGAGCGAACAAA„ 8875,AA069372„20, 137,GAGGAGCGAACAAAACACCG„

8876,AA069372„20, 131 ,CGAACAAAACACCGAACCAC„

8877,AA069372„20,125,AAACACCGAACCACCTAAGA„

8878,AA069372„20,119,CGAACCACCTAAGANGAGAA„

8S79,AA069372„20,113,ACCTAAGANGAGAAAAGGAG„ 8880,AA069372„20,107,GANGAGAAAAGGAGCCGGGA„

8881 ,AA069372„20, 101 ,AAAAGGAGCCGGGATTCCTA„

8882,AA069372„20,95,AGCCGGGATTCCTACCTTCT„

8883,AA069372„20,89,GATTCCTACCTTCTTCCTCG„

8884,AA069372„20,83,TACCTTCTTCCTCGAGCGCG„ 8885,AA069372„20,77,CTTCCTCGAGCGCGCTAACA„

8886,AA069372„20,71,CGAGCGCGCTAACATAGCGT„

8887,AA069372„20,65,CGCTAACATAGCGTTATTAA„

8888,AA069372„20,₅9,CATAGCGTTATTAACAATTG„

8889,AA069372„20,₅3,GTTATTAACAATTGGAAATC„ 8890,AA069372„20,47,AACAATTGGAAATCCTAGCA„ 8891,AA069372„20,41,TGGAAATCCTAGCAGTAAAG„

8892,AA069372„20,35,TCCTAGCAGTAAAGTTCTCG„

8893,AA069372„20,29,CAGTAAAGTTCTCGACACTG„

8894,AA069372„20,23,AGTTCTCGACACTGGACAGG„

8895,AA069372„20,17,CGACACTGGACAGGGCAGTC„

8896,AA069372„20,11,TGGACAGGGCAGTCCCTTGG„

8897,AA069372„20,5,GGGCAGTCCCTTGGTGCAGA„

(GENBANK ACCESSION NO. T74688)

NAGCNNNAAGTATTATTTCATTTTATTATTCCAAAGAATCAAGCCCATCATGAGTAGCCCACATGGTTGCTGTTCAAAGGTACTGAA

AAGGGAGGCATTTGGTCACCATTACCCATCAAGGAACTCTTTACAAGGATAGGTCCAAGTCCTTCGTGCTGCTCTTGGTCATTCAGT

GACTGCAGTTTTGGCCCAGAAGCCATCCAAGATGAGCAAGTGCTGAGCCATCCTTAACTCATACCTAGATGAAACAACTTGCGCAG

AAACGCTGGTCCTCCCCAGTAACCCCTTAGCATCATATTCCAATACAGGAAAGGCATCAGGTCAGCTTTCATGAGATACATGGGAA

AGGCGCTCTTTGCTTTGATCAAAGGGGAAGGTTTCTAGCGGCTCTGCTTTTGTAGGTCAAACTCAGGCAAGATTCACACGGTTGTAG

GCCGGTCANCAGTGGGACATGGATGTGTAGGCCATCATACTTCTTTGTTGGGGGTTTNGATTCTNCATAATTNCAGGAANTTGTCCT

ATCAAGGATTCCTGACT

(SEQ LD NO: 8898)

8899,T74688„20,518,AGTCAGGAATCCTTGATAGG„ 8900,T74688„20,512,GAATCCTTGATAGGACAANT„ 8901,T74688„20,506,TTGATAGGACAANTTCCTGN„

8902,T74688„20,500,GGACAANTTCCTGNAATTAT„ 8903,T74688„20,494,NTTCCTGNAATTATGNAGAA„ 8904,T74688„20,488,GNAATTATGNAGAATCNAAA„ 8905,T74688„20,482,ATGNAGAATCNAAACCCCCA„ 8906,T74688„20,476,AATCNAAACCCCCAACAAAG„

8907,T74688„20,470,AACCCCCAACAAAGAAGTAT„ 8908,T74688„20,464,CAACAAAGAAGTATGATGGC„ 8909,T74688„20,458,AGAAGTATGATGGCCTACAC„ 8910,T74688„20,452,ATGATGGCCTACACATCCAT„ 8911,T74688„20,446,GCCTACACATCCATGTCCCA„

8912,T74688„20,440,ACATCCATGTCCCACTGNTG„ 8913,T74688„20,434,ATGTCCCACTGNTGACCGGC„ 8914,T74688„20,428,CACTGNTGACCGGCCTACAA„ 8915,T74688„20,422,TGACCGGCCTACAACCGTGT„ 8916,T74688„20,416,GCCTACAACCGTGTGAATCT„

8917,T74688„20,410,AACCGTGTGAATCTTGCCTG„ 8918,T74688„20,404,GTGAATCTTGCCTGAGTTTG„ 8919,T74688„20,398,CTTGCCTGAGTTTGACCTAC„ 8920,T74688„20,392,TGAGTTTGACCTACAAAAGC„ 8921,T74688„20,386,TGACCTACAAAAGCAGAGCC„

8922,T74688„20,380,ACAAAAGCAGAGCCGCTAGA„ 8923,T74688„20,374,GCAGAGCCGCTAGAAACCTT„ 8924,T74688„20,368,CCGCTAGAAACCTTCCCCTT„ 8925,T74688„20,362,GAAACCTTCCCCTTTGATCA„ 8926,T74688„20,356,TTCCCCTTTGATCAAAGCAA„

8927,T74688„20,350,TTTGATCAAAGCAAAGAGCG„ 8928,T74688„20,344,CAAAGCAAAGAGCGCCTTTC„ 8929,T74688„20,338,AAAGAGCGCCTTTCCCATGT„ 8930,T74688„20,332,CGCCTTTCCCATGTATCTCA„ 8931,T74688„20,326,TCCCATGTATCTCATGAAAG„

8932,T74688„20,320,GTATCTCATGAAAGCTGACC„ 8933,T74688„20,314,CATGAAAGCTGACCTGATGC„ 8934,T74688„20,308,AGCTGACCTGATGCCTTTCC„ 8935,T74688„20,302,CCTGATGCCTTTCCTGTATT„ 8936,T74688„20,296,GCCTTTCCTGTATTGGAATA„

8937,T74688„20,290,CCTGTATTGGAATATGATGC„ 8938,T74688„20,284,TTGGAATATGATGCTAAGGG„ 8939,T74688„20,278,TATGATGCTAAGGGGTTACT„ 8940,T74688„20,272,GCTAAGGGGTTACTGGGGAG„ 8941,T74688„20,266,GGGTTACTGGGGAGGACCAG„

8942,T74688„20,260,CTGGGGAGGACCAGCGTTTC„ 8943,T74688„20,254,AGGACCAGCGTTTCTGCGCA„ 8944,T74688„20,248,AGCGTTTCTGCGCAAGTTGT„ 8945,T74688„20,242,TCTGCGCAAGTTGTTTCATC„ 8946,T74688„20,236,CAAGTTGTTTCATCTAGGTA„

8947,T74688„20,230,GTTTCATCTAGGTATGAGTT„ 8948,T74688„20,224,TCTAGGTATGAGTTAAGGAT„ 8949,T74688„20,218,TATGAGTTAAGGATGGCTCA„ 8950,T74688„20,212,TTAAGGATGGCTCAGCACTT„ 8951,T74688„20,206,ATGGCTCAGCACTTGCTCAT„

8952,T74688„20,200,CAGCACTTGCTCATCTTGGA„ 8953,T74688,,20,194,TTGCTCATCTTGGATGGCTT„ 8954,T74688„20, 188,ATCTTGGATGGCTTCTGGGC„ 8955,T74688„20, 182,GATGGCTTCTGGGCCAAAAC„ 8956,T74688„20,176,TTCTGGGCCAAAACTGCAGT„ 8957,T74688„20,170,GCCAAAACTGCAGTCACTGA„

8958,T74688„20,164,ACTGCAGTCACTGAATGACC„

8959,T74688„20,158,GTCACTGAATGACCAAGAGC„

8960,T74688„20,I52,GAATGACCAAGAGCAGCACG„ 8961,T74688„20,146,CCAAGAGCAGCACGAAGGAC„

8962,T74688„20,140,GCAGCACGAAGGACTTGGAC„

8963,T74688„20,134,CGAAGGACTTGGACCTATCC„

8964,T74688„20,128,ACTTGGACCTATCCTTGTAA„

8965,T74688„20,122,ACCTATCCTTGTAAAGAGTT„ 8966,T74688„20,116,CCTTGTAAAGAGTTCCTTGA„

8967,T74688„20, 110,AAAGAGTTCCTTGATGGGTA„

8968,T74688„20,104,TTCCTTGATGGGTAATGGTG„

8969,T74688„20,98,GATGGGTAATGGTGACCAAA„

8970,T74688„20,92,TAATGGTGACCAAATGCCTC„ 8971 ,T74688„20,86,TGACCAAATGCCTCCCTTTT„

8972,T74688„20,80,AATGCCTCCCTTTTCAGTAC„

8973,T74688„20,74,TCCCTTTTCAGTACCTTTGA„

8974,T74688„20,68,TTCAGTACCTTTGAACAGCA„

8975,T74688„20,62,ACCTTTGAACAGCAACCATG„ 8976,T74688„20,56,GAACAGCAACCATGTGGGCT„

8977,T74688„20,50,CAACCATGTGGGCTACTCAT„

8978,T74688„20,44,TGTGGGCTACTCATGATGGG„

8979,T74688„20,38,CTACTCATGATGGGCTTGAT„

8980,T74688„20,32,ATGATGGGCTTGATTCTTTG„ 8981 ,T74688„20,26,GGCTTGATTCTTTGGAATAA„

8982,T74688„20,20,ATTCTTTGGAATAATAAAAT„

8983 74688„20,14,TGGAATAATAAAATGAAATA„

8984,T74688„20,8,AATAAAATGAAATAATACTT„

8985,T74688„20,2,ATGAAATAATACTTNNNGCT„ (GENBANK ACCESSION NO. AA187351)

ATCTTCCCCATCGAGTACCATGATATCTGGCAGATGTATAAGAAGGCAGAGGCTTCCTTTTGGACCGCCGAGGAGGTGGACCTCTCC

AAGGACATTCAGCACTGGGAATCCCTGAAACCCGAGGAGAGATATTTTATATCCCATGTTCTGGCTTTCTTTGCAGCAAGCGATGGC

ATAGTAAATGAAAACTTGGTGGAGCGATTTAGCCAAGAAGTTCAGATTACAGAAGCCCGCTGTTTCTATGGCTTCCAAATTGCCATG

GAAAACATACATTCTGAAATGTATAGTCTTCTTATTGACACTTACATAAAAGNTCCCAAAGAAAGGGAATTTCTCTTCAATGCCATT GNAACGNTGCCTTGTGTCAAGAAGAAGGCAGACTGGGCCTTGCGCTGGATTGGGGACAAAGAGGCTACCTATGGTGAACGTGTTGT

AGC

(SEQ LD NO: 8986)

8987,AA187351„20,418,GCTACAACACGTTCACCATA„ 8988,AA187351„20,412,ACACGTTCACCATAGGTAGC„

8989,AA187351„20,406,TCACCATAGGTAGCCTCTTT„

8990.AA 187351 „20,400,TAGGTAGCCTCTTTGTCCCC„

8991,AA187351„20,394,GCCTCTTTGTCCCCAATCCA„

8992,AA187351„20,388,TTGTCCCCAATCCAGCGCAA„ 8993,AA187351„20,3S2,CCAATCCAGCGCAAGGCCCA„

8994,AA187351„20,376,CAGCGCAAGGCCCAGTCTGC„

8995,AA187351„20,370,AAGGCCCAGTCTGCCTTCTT„

8996,AA187351„20,364,CAGTCTGCCTTCTTCTTGAC„

8997,AA187351„20,358,GCCTTCTTCTTGACACAAGG„ 8998,AA187351„20,352,TTCTTGACACAAGGCANCGT„

8999,AA187351„20,346,ACACAAGGCANCGTTNCAAT„

9000,AA187351„20,340,GGCANCGTTNCAATGGCATT„

9001 ,AA187351 „20,334,GTTNCAATGGCATTGAAGAG„

9002,AA187351„20,328,ATGGCATTGAAGAGAAATTC„ 9003,AA187351„20,322,TTGAAGAGAAATTCCCTTTC„

9004.AA187351 „20,316,AGAAATTCCCTTTCTTTGGG„

9005,AA187351„20,310,TCCCTTTCTTTGGGANCTTT„

9006,AA187351„20,304,TCTTTGGGANCTTTTATGTA„

9007₎AA187351„20,298,GGANCTTTTATGTAAGTGTC„ 9008,AA187351„20,292,TTTATGTAAGTGTCAATAAG„

9009,AA187351„20,286,TAAGTGTCAATAAGAAGACT„

9010.AA187351 „20,280,TCAATAAGAAGACTATACAT„

9011 ,AA187351 „20,274,AGAAGACTATACATTTCAGA„

9012,AA187351„20,268,CTATACATTTCAGAATGTAT„ 9013,AA187351„20,262,ATTTCAGAATGTATGTTTTC„

9014.AA187351 „20,256,GAATGTATGTTTTCCATGGC„

9015,AA187351„20,250,ATGTTTTCCATGGCAATTTG„

9016.AA187351 „20,244,TCCATGGCAATTTGGAAGCC„

9017,AA187351„20,238,GCAATTTGGAAGCCATAGAA„ 9018,AA187351„20,232,TGGAAGCCATAGAAACAGCG„

9019.AA187351 „20,226,CCATAGAAACAGCGGGCTTC„

9020,AA 187351 „20,220,AAACAGCGGGCTTCTGTAAT„

9021 187351 „20,214,CGGGCTTCTGTAATCTGAAC„

9022,AA187351„20,208,TCTGTAATCTGAACTTCTTG„ 9023,AA187351„20,202,ATCTGAACTTCTTGGCTAAA„ 9024.AA187351 ,,20,196,ACTTCTTGGCTAAATCGCTC„

9025,AA187351 „20, 190,TGGCTAAATCGCTCCACCAA„

9026.AA187351 „20, 184,AATCGCTCCACCAAGTTTTC„

9027,AA187351„20,178,TCCACCAAGTTTTCATTTAC„ 9028.AA187351„20, 172,AAGTTTTCATTTACTATGCC„

9029,AA187351„20,166,TCATTTACTATGCCATCGCT„

9030,AA187351 „20, 160,ACTATGCCATCGCTTGCTGC„

9031 ,AA 187351 „20, 154,CCATCGCTTGCTGCAAAGAA„

9032,AA187351„20,148,CTTGCTGCAAAGAAAGCCAG„ 9033,AA187351 „20, 142,GCAAAGAAAGCCAGAACATG„

9034,AA187351„20,136,AAAGCCAGAACATGGGATAT„

9035.AA187351 „20, 130,AGAACATGGGATATAAAATA„

9036,AA187351„20,124,TGGGATATAAAATATCTCTC„

9037.AA187351 „20, 118.ATAAAATATCTCTCCTCGGG,, 9038,AA187351„20,112,TATCTCTCCTCGGGTTTCAG„

9039,AA187351„20,106,TCCTCGGGTTTCAGGGATTC„

9040,AA187351„20,100,GGTTTCAGGGATTCCCAGTG„

9041,AA187351„20,94,AGGGATTCCCAGTGCTGAAT„

9042,AA187351„20,88,TCCCAGTGCTGAATGTCCTT„ 9043,AA187351„20,82,TGCTGAATGTCCTTGGAGAG„

9044.AA187351 „20,76,ATGTCCTTGGAGAGGTCCAC„

9045,AA187351 „20,70,TTGGAGAGGTCCACCTCCTC„

9046,AA187351„20,64,AGGTCCACCTCCTCGGCGGT„

9047.AA 187351 „20,58,ACCTCCTCGGCGGTCCAAAA„ 9048,AA187351„20,52,TCGGCGGTCCAAAAGGAAGC„

9049,AA187351 „20,46,GTCCAAAAGGAAGCCTCTGC„

9050,AA187351„20,40,AAGGAAGCCTCTGCCTTCTT„

9051 ,AA187351 „20,34,GCCTCTGCCTTCTTATACAT„

9052,AA187351„20,28,GCCTTCTTATACATCTGCCA„ 9053,AA187351„20,22,TTATACATCTGCCAGATATC„

9054,AA187351„20,16, ATCTGCCAGATATCATGGTA,,

9055,AA187351„20,10,CAGATATCATGGTACTCGAT„

9056,AA187351„20,4,TCATGGTACTCGATGGGGAA„

(GENBANK ACCESSION NO. AA677₅34) GTAAGTTTAAATTTATTTTTTAAAAATGCTTGTCTTCCTCACTAGACAATCAACTCTATGAGGGCAGAGACTATGTCACCACTGTCCC

ACCAGCACCTGGCACACAGTAGGTACTCAATAAATATATGTTGGAAGGATGGATGGAGGTAATGGATGGAAAGATGGATGGAAGG

ATGAATGGAGGGATGGATGTGACCCAGCTGAAGTGTGAGTAGGAACATTCTCTTATTATGGGTGGAGGAAAGAGAGAGGAGATTGA

GAAAATAAGATAAAATACATrGATGCGCATCATTTTTGGTGTTCGAAAAGTAGGATTGAATTAGGACTAATAAATCTAGAGAATTTT

ACCTCTTTCAATGCCCAAGCCACACTTTTCTATCACTTTGAAACCGAAAAAGTAAATACTTTCCCAACATTTGCTTTGCTGGTAGGAA ATGCTTTAATAAAAATGCAATCTCTAAGTTGCCATGG

(SEQ ID NO: 90₅7)

9058,AA677534„20,452,CCATGGCAACTTAGAGATTG„ 9059,AA677534„20;446,CAACTTAGAGATTGCATTTT„ 9060,AA677534„20,440,AGAGATTGCATTTTTATTAA„

9061,AA677534„20,434,TGCATTTTTATTAAAGCATT„ 9062,AA677534„20,428,TTTATTAAAGCATTTCCTAC„ 9063,AA677534„20,422,AAAGCATTTCCTACCAGCAA„ 9064,AA677₅34„20,416,TTTCCTACCAGCAAAGCAAA„ 9065,AA677534„20,410,ACCAGCAAAGCAAATGTTGG„

9066,AA677534„20,404,AAAGCAAATGTTGGGAAAGT„ 9067,AA677534„20,398,AATGTTGGGAAAGTATTTAC„ 9068,AA677534„20,392,GGGAAAGTATTTACTTTTTC„ 9069,AA677534„20,386,GTATTTACTTTTTCGGTTTC„ 9070,AA677534„20,380,ACTTTTTCGGTTTCAAAGTG„

9071 ,AA677534„20,374,TCGGTTTCAAAGTGATAGAA„ 9072,AA677534„20,368,TCAAAGTGATAGAAAAGTGT„ 9073,AA677534„20,362,TGATAGAAAAGTGTGGCTTG„ 9074,AA677534„20,356,AAAAGTGTGGCTTGGGCATT„ 9075,AA677534„20,350,GTGGCTTGGGCATTGAAAGA„

9076,AA677534„20,344,TGGGCATTGAAAGAGGTAAA„ 9077,AA677534„20,338,TTGAAAGAGGTAAAATTCTC„ 9078,AA677534„20,332,GAGGTAAAATTCTCTAGATT„ 9079,AA677534„20,326,AAATTCTCTAGATTTATTAG„ 9080,AA677534„20,320,TCTAGATTTATTAGTCCTAA„

9081,AA677534„20,314,TTTATTAGTCCTAATTCAAT„ 9082,AA677534„20,308,AGTCCTAATTCAATCCTACT„ 9083,AA677534„20,302,AATTCAATCCTACTTTTCGA„ 9084,AA677534„20,296,ATCCTACTTTTCGAACACCA„ 9085,AA677534„20,290,CTTTTCGAACACCAAAAATG„

9086,AA677534„20,284,GAACACCAAAAATGATGCGC„ 9087,AA677534„20,278,CAAAAATGATGCGCATCAAT„ 9088,AA677534„20,272,TGATGCGCATCAATGTATTT„ 9089,AA677534„20,266,GCATCAATGTATTTTATCTT„ 9090,AA677534„20,260,ATGTATTTTATCTTATTTTC„ 9091,AA677534„20,254,TTTATCTTATTTTCTCAATC„

9092,AA677534„20,248,TTATTTTCTCAATCTCCTCT„

9093,AA677534„20,242,TCTCAATCTCCTCTCTCTTT„

9094,AA677534„20,236,TCTCCTCTCTCTTTCCTCCA„ 9095,AA677534„20,230,CTCTCTTTCCTCCACCCATA„

9096,AA677534„20,224,TTCCTCCACCCATAATAAGA„

9097,AA677534„20,218,CACCCATAATAAGAGAATGT„

9098,AA677534„20,212,TAATAAGAGAATGTTCCTAC„

9099,AA677₅34„20,206,GAGAATGTTCCTACTCACAC„ 9100,AA677534„20,200,GTTCCTACTCACACTTCAGC„

9101,AA677534„20,194,ACTCACACTTCAGCTGGGTC„

9102,AA677534„20,188,ACTTCAGCTGGGTCACATCC„

9103,AA677534„20,182,GCTGGGTCACATCCATCCCT„

9104,AA677534„20,176,TCACATCCATCCCTCCATTC„ 9105,AA677534„20,170,CCATCCCTCCATTCATCCTT„

9106,AA677534„20, 164,CTCCATTCATCCTTCCATCC„

9107,AA677534„20,158,TCATCCTTCCATCCATCTTT„

9108,AA677534„20, 152.TTCCATCCATCTTTCCATCC,,

9109,AA677534„20,146,CCATCTTTCCATCCATTACC„ 9110,AA677534„20,14O,TTCCATCCATTACCTCCATC„

9111,AA677534„20,134,CCATTACCTCCATCCATCCT„

9112,AA677534„20,128,CCTCCATCCATCCTTCCAAC„

9113,AA677534„20,122,TCCATCCTTCCAACATATAT„

9114,AA677534„20,116,CTTCCAACATATATTTATTG„ 9115,AA677534„20, 110,ACATATATTTATTGAGTACC„

9116,AA677534„20,104,ATTTATTGAGTACCTACTGT„

9117,AA677534„20,98,TGAGTACCTACTGTGTGCCA„

9118,AA677534„20,92,CCTACTGTGTGCCAGGTGCT„

9119,AA677534„20,86,GTGTGCCAGGTGCTGGTGGG„ 9120,AA677534„20,80,CAGGTGCTGGTGGGACAGTG„

9121 ,AA677534„20,74,CTGGTGGGACAGTGGTGACA„

9122,AA677534„20,68,GGACAGTGGTGACATAGTCT„

9123,AA677₅34„20,62,TGGTGACATAGTCTCTGCCC„

9124,AA677534„20,56,CATAGTCTCTGCCCTCATAG„ 9125,AA677534„20,50,CTCTGCCCTCATAGAGTTGA„

9126,AA677534„20,44,CCTCATAGAGTTGATTGTCT„

9127,AA677534„20,38,AGAGTTGATTGTCTAGTGAG„

9128,AA677534„20,32,GATTGTCTAGTGAGGAAGAC„

9129,AA677534„20,26,CTAGTGAGGAAGACAAGCAT„ 9130,AA677534„20,20,AGGAAGACAAGCATTTTTAA„

9131 ,AA677534„20, 14,ACAAGCATTTTTAAAAAATA„

9132,AA677534„20,8,ATTTTTAAAAAATAAATTTA„

9133,AA677534„20,2,AAAAAATAAATTTAAACTTA„

(GENBANK ACCESSION NO. T59658) TCATAGGTAAAATTTTTATTTATGAATGTGTGGACACATGACTTTGGATCCAGCCAGCCAGTGACATAAATAAACTTGAGCAAAAGT

TTCAAGCTAGAGGATATATATGTATAGAAAATTATATATTTGTGTGTGTGTGTAAGGCCTCTTGGAACAGTGCCACAAACCTGGACA

CCAACCAACAGAATACTCCCGTCCTTTGAAATTTCCATTAAGAGCACAATGGGGGTAATTATACCAGGGATGCTCCAATCGCTCTTT

CCATCTTGTGCACTCACATGCCCGCCAAACATGGAAATGTTCGCCTTCTCCCTTCCAATGTGATGGGTTGTTGGAACTTATCTTTAGG

TGGTCATTTGATAGGCCTTTGTGCTCACAGNGGAGGACATCCCACTGNACCCAGCCACTGGGTCATTGTCTATACCAGTTCACATNC AAGGCAGGGCGCACTTTGTCAGGGTTTCCACTCGGAATATCCATTTCGGCATCTGGAGGTACAGTATCGNAGGTGACTAGGATCATT

TGAGGCTTTTTTCTTT

(SEQ LD NO: 9134)

9135,T59658„20,520,AAAGAAAAAAGCCTCAAATG„ 9136,T59658„20,514,AAAAGCCTCAAATGATCCTA„

9137,T596₅8„20,508,CTCAAATGATCCTAGTCACC„

9138,T596₅8„20,502,TGATCCTAGTCACCTNCGAT„

9139,T59658„20,496,TAGTCACCTNCGATACTGTA„

9140,T₅96₅8„20,490,CCTNCGATACTGTACCTCCA„ 9141,T₅96₅8„20,484,ATACTGTACCTCCAGATGCC„

9142,T59658„20,478,TACCTCCAGATGCCGAAATG„

9143,T59658„20,472,CAGATGCCGAAATGGATATT„

9144,T59658,,20,466,CCGAAATGGATATTCCGAGT„

9145,T59658„20,460,TGGATATTCCGAGTGGAAAC„ 9146,T59658„20,454,TTCCGAGTGGAAACCCTGAC„

9147,T59658„20,448,GTGGAAACCCTGACAAAGTG„

9148,T59658„20,442,ACCCTGACAAAGTGCGCCCT„

9149,T59658„20,436,ACAAAGTGCGCCCTGCCTTG„

9150,T59658„20,430,TGCGCCCTGCCTTGNATGTG„ 9151,T59658„20,424,CTGCCTTGNATGTGAACTGG„

9152,T59658„20,418,TGNATGTGAACTGGTATAGA„

9153,T59658„20,412,TGAACTGGTATAGACAATGA„

9154,T59658„20,406,GGTATAGACAATGACCCAGT„

9155,T59658„20,400,GACAATGACCCAGTGGCTGG„ 9156,T59658„20,394,GACCCAGTGGCTGGGTNCAG„ 9157,T59658„20,388,GTGGCTGGGTNCAGTGGGAT„

9158,T59658„20,382,GGGTNCAGTGGGATGTCCTC„

91₅9,T59658„20,376,AGTGGGATGTCCTCCNCTGT„

9160,T59658„20,370,ATGTCCTCCNCTGTGAGCAC„ 9161,T59658„20,364,TCCNCTGTGAGCACAAAGGC„

9162,T59658„20,358,GTGAGCACAAAGGCCTATCA„

9163,T59658„20,352,ACAAAGGCCTATCAAATGAC„

9164,T59658„20,346,GCCTATCAAATGACCACCTA„

916_5>T₅9658„20,340,CAAATGACCACCTAAAGATA„ 9166,T59658„20,334,ACCACCTAAAGATAAGTTCC„

9167,T59658„20,328,TAAAGATAAGTTCCAACAAC„

9168_ST59658„20,322,TAAGTTCCAACAACCCATCA„

9169,T59658„20,316,CCAACAACCCATCACATTGG„

9170,T59658„20,310,ACCCATCACATTGGAAGGGA„ 9171,T59658„20,304,CACATTGGAAGGGAGAAGGC„

9172,T59658„20,298,GGAAGGGAGAAGGCGAACAT„

9173,T59658„20,292,GAGAAGGCGAACATTTCCAT„

9174,T59658„20,286,GCGAACATTTCCATGTTTGG„

9175,T59658„20,280,ATTTCCATGTTTGGCGGGCA„ 9176_;T59658„20,274,ATGTTTGGCGGGCATGTGAG„

9177,T59658„20,268,GGCGGGCATGTGAGTGCACA„

9178,T59658„20,262,CATGTGAGTGCACAAGATGG„

9179,T59658„20,256,AGTGCACAAGATGGAAAGAG„

9180,T59658„20,250,CAAGATGGAAAGAGCGATTG„ 9181 ,T59658„20,244,GGAAAGAGCGATTGGAGCAT„

9182,T59658„20,238,AGCGATTGGAGCATCCCTGG„

9183,T59658„20,232,TGGAGCATCCCTGGTATAAT„

9184,T59658„20,226,ATCCCTGGTATAATTACCCC„

9185,T59658„20,220,GGTATAATTACCCCCATTGT„ 9186,T59658„20,214,ATTACCCCCATTGTGCTCTT„

9187,T59658„20,208,CCCATTGTGCTCTTAATGGA„

9188,T59658„20,202,GTGCTCTTAATGGAAATTTC„

9189,T59658„20,196,TTAATGGAAATTTCAAAGGA„

9190,T59658„20, 190,GAAATTTCAAAGGACGGGAG„ 9191 ,T59658„20, 184,TCAAAGGACGGGAGTATTCT„

9192,T59658„20,178,GACGGGAGTATTCTGTTGGT„

9193,T59658„20,172,AGTATTCTGTTGGTTGGTGT„

9194,T59658„20, 166,CTGTTGGTTGGTGTCCAGGT„

9195,T59658„20,160,GTTGGTGTCCAGGTTTGTGG„ 9196,T59658„20,154,GTCCAGGTTTGTGGCACTGT„

9197,T59658„20,148,GTTTGTGGCACTGTTCCAAG„

9198,T59658„20,142,GGCACTGTTCCAAGAGGCCT„

9199,T59658„20,136,GTTCCAAGAGGCCTTACACA„

9200,T59658„20,130,AGAGGCCTTACACACACACA„ 9201,T59658„20,124,CTTACACACACACACAAATA„

9202,T59658„20, 118,CACACACACAAATATATAAT„

9203,T59658„20,112,CACAAATATATAATTTTCTA„

9204,T59658„20,106,TATATAATTTTCTATACATA„

9205,T59658„20,100,ATTTTCTATACATATATATC„ 9206,T59658„20,94,TATACATATATATCCTCTAG„

9207,T59658„20,88,TATATATCCTCTAGCTTGAA„

9208,T59658„20,82,TCCTCTAGCTTGAAACTTTT„

9209,T59658„20,76,AGCTTGAAACTTTTGCTCAA„

9210,T59658„20,70,AAACTTTTGCTCAAGTTTAT„ 9211,T59658„20,64,TTGCTCAAGTTTATTTATGT„

9212,T59658„20,58,AAGTTTATTTATGTCACTGG„

9213,T59658„20,52,ATTTATGTCACTGGCTGGCT„

9214,T59658„20,46,GTCACTGGCTGGCTGGATCC„

9215,T59658„20,40,GGCTGGCTGGATCCAAAGTC„ 9216,T59658„20,34,CTGGATCCAAAGTCATGTGT„

9217,T59658„20,28,CCAAAGTCATGTGTCCACAC„

9218,T59658„20,22,TCATGTGTCCACACATTCAT„

9219,T59658„20, 16,GTCCACACATTCATAAATAA„

9220,T59658„20,10,ACATTCATAAATAAAAATTT„ 9221 ,T59658„20,4,ATAAATAAAAATTTTACCTA„

(GENBANK ACCESSION NO. AA284245)

CACTCCTCCAGTAGCGGCTGACGTCGTCAATGGCCGCTATGAGGAGGTGAGCGTGTCCGGCTTCGAGGAGTTCCACCGGGCCGTGG

AACAGCACAATGGCAAGACCATTTTCGCCTACTTTACGGGTTCTAAGGACGCCGGGGGGAAAAGCTGGTGCCCCGACTGCGTGCGG

CTGAACCAGTCGTACGAGAGGGGCTGAAGCACATTAGTGAAGGATGTGTGTTCATCTACTGCCAAGTAGGAGAAAAGCCTTATTGG AAAGATCCAAATAATGACTTCAGAAAAAACTTGAAAGTAACAGCAGTGCCTACACTACTTAAGTATGGAACACCTCAAAAACTGGT

AGAATCTGAGTGTCTTCAGGCCAACCTGGTGGAAATGTTGTTCTCTGAAGATTAAGATTTTAGGATGGCAATCA

(SEQ ID NO: 9222)

9223,AA284245„20,399,TGATTGCCATCCTAAAATCT„ 9224,AA284245„20,393,CCATCCTAAAATCTTAATCT„ 9225,AA284245„20,387,TAAAATCTTAATCTTCAGAG„ 9226,AA28424₅„20,381,CTTAATCTTCAGAGAACAAC„ 9227,AA284245„20,375,CTTCAGAGAACAACATTTCC„ 9228,AA284245„20,369,AGAACAACATTTCCACCAGG„ 9229,AA284245„20,363,ACATTTCCACCAGGTTGGCC„

9230,AA284245„20,357,CCACCAGGTTGGCCTGAAGA„ 9231,AA284245„20,351,GGTTGGCCTGAAGACACTCA„ 9232,AA284245„20,345,CCTGAAGACACTCAGATTCT„ 9233,AA284245„20,339,GACACTCAGATTCTACCAGT„ 9234,AA284245„20,333,CAGATTCTACCAGTTTTTGA„

9235,AA284245„20,327,CTACCAGTTTTTGAGGTGTT„ 9236,AA284245„20,321 ,GTTTTTGAGGTGTTCCATAC„ 9237,AA284245„20,315,GAGGTGTTCCATACTTAAGT„ 9238,AA284245„20,309,TTCCATACTTAAGTAGTGTA„ 9239,AA284245„20,303,ACTTAAGTAGTGTAGGCACT„

9240,AA284245„20,297,GTAGTGTAGGCACTGCTGTT„ 9241,AA284245„20,291,TAGGCACTGCTGTTACTTTC„ 9242,AA284245„20,285,CTGCTGTTACTTTCAAGTTT„ 9243,AA284245„20,279,TTACTTTCAAGTTTTTTCTG„ 9244,AA284245„20,273,TCAAGTTTTTTCTGAAGTCA„

9245,AA284245„20,267,TTTTTCTGAAGTCATTATTT„ 9246,AA284245„20,261,TGAAGTCATTATTTGGATCT„ 9247,AA284245„20,255,CATTATTTGGATCTTTCCAA„ 9248,AA284245„20,249,TTGGATCTTTCCAATAAGGC„ 9249,AA284245„20,243,CTTTCCAATAAGGCTTTTCT„ 9250,AA284245„20,237,AATAAGGCTTTTCTCCTACT„ 9251,AA284245„20,231,GCTTTTCTCCTACTTGGCAG„ 9252,AA284245„20,225,CTCCTACTTGGCAGTAGATG„ 9253,AA284245„20,219,CTTGGCAGTAGATGAACACA„ 9254,AA284245„20,213,AGTAGATGAACACACATCCT„

9255,AA284245„20,207,TGAACACACATCCTTCACTA„ 9256,AA284245„20,201 ,CACATCCTTCACTAATGTGC„ 9257,AA284245„20, 195,CTTCACTAATGTGCTTCAGC„ 9258,AA284245„20, 189,TAATGTGCTTCAGCCCCTCT„ 9259,AA284245„20, 183,GCTTCAGCCCCTCTCGTACG„

9260,AA284245„20, 177,GCCCCTCTCGTACGACTGGT„ 9261 ,AA284245„20, 171 ,CTCGTACGACTGGTTCAGCC„ 9262,AA284245„20,165,CGACTGGTTCAGCCGCACGC„ 9263,AA284245„20,159,GTTCAGCCGCACGCAGTCGG„ 9264,AA284245„20,153,CCGCACGCAGTCGGGGCACC„

9265,AA284245„20,147,GCAGTCGGGGCACCAGCTTT„ 9266,AA284245„20, 141 ,GGGGCACCAGCTTTTCCCCC„ 9267,AA284245„20,135,CCAGCTTTTCCCCCCGGCGT„ 9268,AA284245„20,129,TTTCCCCCCGGCGTCCTTAG„ 9269,AA284245„20,123,CCCGGCGTCCTTAGAACCCG„

9270,AA284245„20, 117,GTCCTTAGAACCCGTAAAGT„ 9271,AA284245„20,111,AGAACCCGTAAAGTAGGCGA„ 9272,AA284245„20,105,CGTAAAGTAGGCGAAAATGG„ 9273,AA284245„20,99,GTAGGCGAAAATGGTCTTGC„ 9274,AA284245„20,93,GAAAATGGTCTTGCCATTGT„

9275,AA284245„20,87,GGTCTTGCCATTGTGCTGTT„ 9276,AA284245„20,81 ,GCCATTGTGCTGTTCCACGG„ 9277,AA284245„20,75,GTGCTGTTCCACGGCCCGGT„ 9278,AA284245„20,69,TTCCACGGCCCGGTGGAACT„ 9279,AA284245„20,63,GGCCCGGTGGAACTCCTCGA„

9280,AA284245„20,57,GTGGAACTCCTCGAAGCCGG„ 9281 ,AA284245„20,51 ,CTCCTCGAAGCCGGACACGC„ 9282,AA284245„20,45,GAAGCCGGACACGCTCACCT„ 9283,AA284245„20,39,GGACACGCTCACCTCCTCAT„ 9284,AA284245„20,33,GCTCACCTCCTCATAGCGGC„

9285,AA284245„20,27,CTCCTCATAGCGGCCATTGA„ 9286,AA284245„20,21 ,ATAGCGGCCATTGACGACGT„ 9287,AA284245„20, 15,GCCATTGACGACGTCAGCCG„ 9288,AA284245„20,9,GACGACGTCAGCCGCTACTG„ 9289,AA284245„20,3,GTCAGCCGCTACTGGAGGAG„

(GENBANK ACCESSION NO. H05914)

GATTTATACACTGGATCCCAGGGATGTGACTCACTGGGAAAAAATGTTGGACTAGGCATGTTCAGTGAAGGAGCCAGGNAGTTATA

TAACACACGGTAAACATCCACCTGGCTCAAGGGGCAAATGCAGTACGTACAGCATTGGCAGTGGTGCGTCAGAGGTGGCAGAACTN

TTTCACACTAACCAGTTGANGACTACACAAGATTAATACCATCCAGCATCAGGNTATAGCNTGTGGATTTTACAAACCATTTCTTAT

TTCTAACTTTCAGGNGTTGATGTTTTTCCCAGTCCNTCTTAAAATTTTTACTGCTT

(SEQ ID NO: 9290)

9291 ,H05914„20,472,AAGCAGTAAAAATTTTAAGA„ 9292,H05914_; ,20,466,TAAAAATTTTAAGANGGACT„ 9293,H05914_: ,20,460,TTTTAAGANGGACTGGGAAA„ 9294.H05914_: ,20,454,GANGGACTGGGAAAAACATC„ 9295,H05914_: ,20,448,CTGGGAAAAACATCAACNCC„ 9296,H05914_; ,20,442,AAAACATCAACNCCTGAAAG„ 9297,H05914_; ,20,436,TCAACNCCTGAAAGTTAGAA„ 9298,H05914_; ,20,430,CCTGAAAGTTAGAAATAAGA„ 9299,H05914_; ,20,424,AGTTAGAAATAAGAAATGGT„ 9300,H05914_; ,20,418,AAATAAGAAATGGTTTGTAA„ 9301,H05914_; ,20,412,GAAATGGTTTGTAAAATCCA„ 9302.H05914_: ,20,406,GTTTGTAAAATCCACANGCT„ 9303.H05914_: ,20,400,AAAATCCACANGCTATANCC„ 9304,H05914_; ,20,394,CACANGCTATANCCTGATGC„ 9305,H05914_; ,20,388,CTATANCCTGATGCTGGATG„ 9306.H05914, ,20,382,CCTGATGCTGGATGGTATTA„ 9307,H05914 ,20,376,GCTGGATGGTATTAATCTTG„ 9308,H05914_; ,20,370,TGGTATTAATCTTGTGTAGT„ 9309.H05914_: ,20,364,TAATCTTGTGTAGTCNTCAA„ 9310.H05914_: ,20,358,TGTGTAGTCNTCAACTGGTT„ 9311.H05914, ,20,352,GTCNTCAACTGGTTAGTGTG„ 9312.H05914_: ,20,346,AACTGGTTAGTGTGAAANAG„ 9313.H05914, ,20,340,TTAGTGTGAAANAGTTCTGC„ 9314.H05914_: ,20,334,TGAAANAGTTCTGCCACCTC„ 9315,H05914, ,20,328,AGTTCTGCCACCTCTGACGC„ 9316,H05914_; ,20,322,GCCACCTCTGACGCACCACT„ 9317,H0₅914_: ,20,316,TCTGACGCACCACTGCCAAT„ 9318.H05914, ,20,310,GCACCACTGCCAATGCTGTA„ 9319.H05914. ,20,304,CTGCCAATGCTGTACGTACT„ 9320,H05914_: ,20,298,ATGCTGTACGTACTGCATTT„ 9321.H05914, ,20,292,TACGTACTGCATTTGCCCCT„ 9322.H05914, ,20,286,CTGCATTTGCCCCTTGAGCC„ 9323,H05914_: ,20,280,TTGCCCCTTGAGCCAGGTGG„ 9324,H05914_: ,20,274,CTTGAGCCAGGTGGATGTTT„ 9325.H05914_: ,20,268,CCAGGTGGATGTTTACCGTG„ 9326,H05914_: ,20,262,GGATGTTTACCGTGTGTTAT„ 9327.H05914. ,20,256,TTACCGTGTGTTATATAACT„ 9328,H05914_; ,20,250,TGTGTTATATAACTNCCTGG„ 9329,H05914_; ,20,244,ATATAACTNCCTGGCTCCTT„ 9330.H05914 ,20,238,CTNCCTGGCTCCTTCACTGA„ 9331.H05914 ,20,232,GGCTCCTTCACTGAACATGC„ 9332.H05914 ,20,226,TTCACTGAACATGCCTAGTC„ 9333.H05914 ,20,220,GAACATGCCTAGTCCAACAT„ 9334,H05914_: 9335.H05914 ,20^208 CCAACATTTTTTCCCAGTG^ 9336.H05914 ,20,202,ATTTTTTCCCAGTGAGTCAC„ 9337.H05914 ,20, 196,TCCCAGTGAGTCACATCCCT„ 9338,H05914 ,20, 190,TGAGTCACATCCCTGGGATC„ 9339.H05914 ,20, 184,ACATCCCTGGGATCCAGTGT„ 9340,H05914 ,20,178,CTGGGATCCAGTGTATAAAT„ 9341.H05914. ,20,172,TCCAGTGTATAAATCCAATA„ 9342.H05914. ,20, 166,GTATAAATCCAATATCATGT„ 9343.H05914_: ,20, 160,ATCCAATATCATGTCTTGTG„ 9344,H05914_; ,20, 154,TATCATGTCTTGTGTATAAN„ 9345.H05914 ,20, 148,GTCTTGTGTATAANTCTTCC„ 9346.H05914_: ,20,142,TGTATAANTCTTCCAAAGGA„ 9347,H05914 ,20,136,ANTCTTCCAAAGGATCTTAT„ 9348,H05914_; ,20,130,CCAAAGGATCTTATTTTGTG„ 9349,H0₅914. ,20,124,GATCTTATTTTGTGAACTAT„ 93₅0,H05914_; ,20, 118,ATTTTGTGAACTATATCAGT„ 9351,H05914 ,20,112,TGAACTATATCAGTAGTGTA„ 9352,H05914 ,20,106,ATATCAGTAGTGTACATTAC„ 9353.H05914 ,20,100,GTAGTGTACATTACCATATA„ 9354.H05914 ,20,94,TACATTACCATATAATGTAA„ 9355,H05914 ,20,88,ACCATATAATGTAAAAAGAT„ 9356,H05914 ,20,82,TAATGTAAAAAGATCTACAT„ 9357.H05914 ,20,76,AAAAAGATCTACATACAAAC„ 9358,H0591 ,20,70,ATCTACATACAAACAATGCA„ 9359.H05914. ,20,64,ATACAAACAATGCAACCAAC„ 9360,H05914 ,20,58,ACAATGCAACCAACTATCCA„ 9361.H05914 ,20,52,CAACCAACTATCCAAGTGTT„ 9362,H05914_; ,20,46,ACTATCCAAGTGTTATACCA„ 9363.H05914 ,20,40,CAAGTGTTATACCAACTAAA„ 9364.H05914 ,20,34,TTATACCAACTAAAACCCCC„ 9365,H05914 ,20,28,CAACTAAAACCCCCAATAAA„ 9366,H05914 ,20,22,AAACCCCCAATAAACCTTGA„ 9367,H05914„20,16,CCAATAAACCTTGAACAGTG„ 9368,H05914„20,10,AACCTTGAACAGTGAAANAA„ 9369,H0₅914„20,4,GAACAGTGAAANAAAAAAAA„ SEQ ID NO: Sequences

Human IL4-R

12569 CTCCACTCACTCCAGGTG

12570 CTCCACTCACTCCAG

12571 GCAGCTGCCCCATGCTG 12572 GAGAAGGCCTTGTAACC

12573 GCGCCCCTGCTCCATTCGCC

12574 TTTCTTCCAGCTGTGTGT

12575 CACCACGCCCGGCTTCTCT

12576 TCTGCCCGCCTCAGCCTCC 12577 GGCACCAGGCTGGTCTCG

12578 TGGGAGATGCCAAGGCAC

12579 GCCACCCCATTGGGAGAT

12580 GCAAAGCCACCCCATTGG

12581 GTTCCCAGAGCTTGCCACCT 12582 GGAGCTCGGTGCTGCAATTG

12583 GATACACGTGTGGGCTTCGG

12584 GCGCCTCCGTTGTTCTCAGG

12585 GCAGCTGCTGCCCAGCCC

12586 GGTTTCCTGGGGCCCTGGGT 12587 GGGATACGGGTTGCTCCAG

12588 TCTGCCGGGTCGTTTTCACT

12589 TTCAGGGTGCTGGCTGCG

12590 GGCCCTCACCCGTGCCCTGT

12591 CCACTCACTCCAGGTGGTGT 12592 TGTGCCACTTGGTGCTGG

12593 TGCTGCTCGAAGGGCTCCCT

12594 GGCGGCTGCGGGCTGGGT

12595 CGGGACCGCTTCTCCCACTG

12596 CTTGGCTGGTTCCTGGCCT 12597 TGGCAGCCTTGTGAGGATCT

12598 TCTTGCTGATCTCCACTGGG

12599 GTCATCCCTGCTGCTCTC

12600 TCGTACTTCCCGAAGGTGG

12601 GGTTGTCTGGACTCTGGGT 12602 GTTGCTGAAGCTGCGGT

12603 CGGGTTCTACTTCCTCCAGG

12604 TGCTCCCAGGTTTCTGGCTC

12605 CCCTGCTCCACCGCATGT

12606 GGCTTATACCCCTCTTCCC 12607 TGAGCTCTGCGGACTGCG ιl2608 CTGTTTCAGGTGGCCGC

12609 GGATTTACTCTTCTCTG

12610 GGGTCTGGCTTGAGCTCTG

12611 GCCCTAGTCCTCATCTGC 12612 TGCCAGCCTGGCTGCCTTCC

12613 GCGACCCAGTGCCCTCTACT

12614 GTCTGCTGCAGAAGCTGTGG

12615 GGCTCGGCTTCTAGTTCAG

12616 GTCATTCCCTTGATGGCTG 12617 TCGATTTCCCAAGGCCGCCC

12618 TTCATGTCCTCTGTTGCTCC

12619 GGCATGGGTGTTTGGCAGC

12620 GTGCCTTATGCCTGCTGTCT

12621 TTCTGTTCCACTCTCCTC 12622 AGAAACTTTATTTATACAA

12623 GGCTCCACTCACTCCAG

12624 GGCTCCACTCACTCCA

12625 GCTGGGATTATAGGCATGAG

12626 CCTGATCTCAAGTGATCTGC 12627 ACAGGGAACAGGAGCCCAGA

12628 GCAGCAGGACCAGGCAGCTC

12629 GGCTCCTGCAAGACCTTCAT

12630 TGTAGTCGGAGACGCAGGTG

12631 CTCGCAAGTAGAGATGCTCA 12632 GTGGGACCATTCATCTTCCA

12633 AACCAGCGTGTGGGCTTCGG

12634 AGAGCAGAAAAACCAGCTGG

12635 GATACACGTGTGGGCTTCGG

12636 ACTGACCACGTCATCCATGA 12637 TCCAGTGTATAGTTATCCGC 12638 GAAGGAGCCCTTCCACAGCA

12639 TTCACATGCTCGCTGGGCTT

12640 GACATTGGTGTGAACTGTCA

12641 GTCAGCAGCAGAGTGTCGGA 12642 ATTATACAGGTAATTGTCAG

12643 TTGACTGCATAGGTGAGATG

12644 ATAGATTCTGAAATCTGCCG

12645 GGTTCTAGGTAGGTCACGTT

12646 TGGCTGCGATGCGGAGGGAG 12647 CCCTGTAGGAAATCCCAGAC

12648 TGGCTGCGATGCGGAGGGAG

12649 TATAGCCCTGAGCCCAGGCC

12650 CAGGATGACAATGCAGGAAA

12651 TAGCACAACAGGCAGACGGC 12652 TAATCTTGGTGATGCTGAAC

12653 CTGATCCCACGTAAGAAAGA

12654 TTATTATAGCCACGAGGCGG

12655 ACAATTCTTCCAGTGTGGGC

12656 CGGGACCGCTTCTCCCACTG 12657 ACTTGGCTGGTTCCTGGCCT

12658 TCATCCCTTTTCATGTTGTG

12659 GCCCTGGAAAGGCATCTCTT

12660 GCTCTCTGGCCAGAGGACTG

12661 ACACATCGCACCACGCTGAT 12662 CTCCTCCTCCTCACACTCCA

12663 CAGGCGATGCACAGAAGCTC

12664 ATGCCCTCCCTTCCCTCCTG

12665 TCTCTGTTAGCCGGGCCACA

12666 GAGCAGGTCCAGGAACAGGC 12667 AGGTGGAAGAAGGCATGACT

12668 GGAACTCATCCCAGGGCATG

12669 CTCCTTGGGCCCTGCACTTG

12670 GCTCCAGGTGGAGAGGCTGC

12671 CGGGCTGGCAGGAGGACTTG 12672 AGGGTTGCCTGCGATGACGA

12673 ACGGTGACTGGCTCAGGGAG

12674 TGGACCCAGCTCTCTGGGAC

12675 TGTCTGAAGCTGCGGTAAGC

12676 ACAGTGGTTGGCTCAGAGAG 12677 GGACATTTCGGCGGAGGATC

12678 CAAACTCCTGATAGCCACTG

12679 ACCGCACTGGCCTGGGTGCC

12680 GGCCTTGTAACCAGCCTCTC

12681 CTGGCAAGCAGGCTTGAGAA 12682 GAATGAGGTCTTGGAAAGGC

12683 TGTCCAGTCCAAAGGTGAAC

12684 CTTGGGAGATGTGAGCTCTG

12685 GGCTCCAGACCCAGGTGCTC

12686 GGCTTTGGCATGTCCTCTAC 12687 GGGTCTGTGGCCTGCTCCTG

12688 TGCCCAGGCTGTCCACAAGG

12689 GGCTGAGTAGACAATGCCAC

12690 CCGCACAGGTGGCAGGTAAG

12691 TCCTCCTGGCCATGACACTG 12692 GCCACAGCAAGGACTGGCCA

12693 GACCTGTCTCCACAGCAGCA

12694 CAGACTGGCCTCCAGTGGAA

12695 GGTGCCAGGGAGGCCGGACA

12696 GGGCAGGATGGAAGGATGAT 12697 GTCCCACGGAGACAAAGTTC

12698 AGAGACCCTCATGTATGTGG

12699 CAGGCATGGATAAGCCCTAG

12700 TTCCAGGAGGTGGCATTTCC

12701 GCCAATCACCTTCATACCAT 12702 TCCAGTCTCTGCAGCCCAGT

12703 GTGGCGAGCCCAGCCCAATG

12704 GCCCTCTACTCTCATGGGAT

12705 GAGGTGCCCAAGGGCCTCAG

12706 CAACAACTCGTTCACAAGTC 12707 GAAGCTGTGGAGGGAGCAGC

12708 AACAGGGACAGTCTGCTGCA

12709 AACATGCCTTGGGCAGTTAC

12710 GGCCATGATCTGGTGGGCAA

12711 GGCAGGTGGGCCTCCACGTG 12712 CCTGAAGTTCAATTTCTCAT 12713 TCTAGGCAATGACCACCCTC

12714 CGATTTCCCAAGGCCGCCCA

12715 ACAGCCGGGATTCTGCCTCC

12716 TGCTTTAGTCATAGCAATTT 12717 GTTTGGCAGCAAATTGTCCC

12718 TGGCTGAGCATATTTATTCT

12719 GCCCACAGGGTGGCTGAGCA

12720 CCTGCTGTCTGGATTGCCCG

12721 GCCAACATGCAGGGTAACTG 12722 CCCTAGCACCTGAGGTCTGG

12723 CAACCCAAGGTTCCCGCCTT

12724 ACACACAGACGAGCATTACT IL5R

12725 CCATGCGATGAGAAGCAGCGG 12726 GGTGGCCATGCGATGAGAAGC

12727 CAATGTGCCTGGCCTGAG

12728 TCAGGCACAGGACCAATGCT

12729 ACCAATGCTCAATGTGCC

12730 TAGCGTCAGGCACAGGACC 12731 TCTAGCATAGCGTCAGGCAC

12732 CAGCATCTAGCATAGCGTC

12733 CTATGCTCGTGGCTGCAAC

12734 CGTGTCTATGCTCGTGGCT

12735 CGTGTCTATGCTCGTGGC 12736 GTGTCTGTCGTGTCTATGCTC

12737 GGCGAGGACCGTGTCTGTCG

12738 GGCGAGGACCGTGTCTGT

12739 CAGAAGATGGCGAGGACCGTG

12740 CAGAAGATGGCGAGGACCG 12741 CTCAACAGAAGATGGCGAGG

12742 CCAGTACTCAACAGAAGATGG

12743 TTCCGACCAGTACTCAACAG

12744 CTCTTGTTCCGACCAGTACTC

12745 TCCTCTTGTTCCGACCAG 12746 GACGATCCTCTTGTTCCG

12747 CTACAGACGATCCTCTTG

12748 GCCTGTCTACAGACGATCC

12749 CTGTAGCCTGTCTACAGACG

12750 AATCTGTAGCCTGTCTAC 12751 GATGAGTGAACATGACAGG

12752 TTACTATGAGGATTTAA

12753 GCCACGATGATCATATCCTT

12754 GCCACGATGATCATATCC

12755 GCGCCACGATGATCATAT 12756 ATGCGCCACGATGATCAT

12757 TGCGCCACGATGATCATA

12758 ATACATGCGCCACGATG

12759 GAGTAATACATGCGCCAC

12760 GGATGAGTAATACATGCG 12761 TTGCAGTATCTCAGTGGC

12762 GCTTGCAGTATCTCAGTG

12763 GTCAGCTTGCAGTATCTC

12764 GGAAGTAAGTCAGCTTGCAG

12765 TTGACAGGTGGGAGAAGTGA 12766 CCAGTAACTTTAATGGTG

12767 GATCAGGATTTGGTTTCC

12768 GCTCTTGATCAGGATTTGG

12769 CCTTTGCTCTTGATCAGG

12770 GATTAACATTCCTTTGCTC 12771 CTGGTTTCATAGTCATCTTC

12772 GGTTACACATTTGCTTTCAG

12773 TGTGGAGGATGGTTACAC

12774 GGTTACACATTTGCTTTCAG

12775 GTCGTTCTGCAGGATGGTCCG 12776 GTGGTCGTTCTGCAGGATG

12777 AGTGAGTGGTCGTTCTGC

12778 GCCAGTAGTGAGTGGTCGT

12779 GCTGGCCAGTAGTGAGTG

12780 GCCCAGCTGCTGGCCAGTAGT 12781 GAAGCCCAGCTGCTGGCCA

12782 CAGCAGAAGCCCAGCTGC

12783 GAAGTTCAGCAGAAGCCCA

12784 GGCATGAAGTTCAGCAGAAG

12785 TTCCAGGAGACCCTGGTG 12786 TGAGGTTCCAGGAGACCC 12787 CACAATTGAGGTTCCAGG

12788 GTGTTTGTGGTGCAAGTTA

12789 TGTCTTCTGTAGTGTTTGTGG

12790 GCCAGGTGCAGTGAAGGG 12791 ACAAGCCAGGTGCAGTGA

12792 TGCCAACAAGCCAGGTGC

12793 ATCTGTGCCAACAAGCCA

12794 GGCATCTGTGCCAACAAGCC

12795 CCAAGAGCCATACCTATAG 12796 CAGTCCAAGAGCCATACC

12797 GCATTCTTCAGTCCAAGAGCC

12798 CTTGGCATTCTTCAGTCC

12799 TGCTGTATTCTTGGCATTCTT

12800 CTTTGCTGTATTCTTGGC 12801 CTCCCCAGTGTGTCTTTGCTG

12802 TTCTCCCCAGTGTGTCTT

12803 GATATTTCTCCCCAGTGT

12804 CATGCGATATTTCTCCCC

12805 CCAGCATGCGATATTTCT 12806 GCCAGTCACGCCCTTTGCTG

12807 GCCAGTCACGCCCTTTGC

12808 AGCCGTTAACAAGCACCG

12809 GCTGGAGCCGTTAACAAG

12810 TGCTTGCTGGAGCCGTTA 12811 GCAGAGTGCTTGCTGGAGC

12812 GATAGCAGAGTGCTTGCT

12813 GGGCCTGATAGCAGAGTGC

12814 ATCAATGGCGTGAAGGGC

12815 ATTTGATCAATGGCGTGA 12816 TGTGACATTCAGTGGAGG

12817 TCTCTGCTGTGACATTCAGT

12818 TCAATCTCTGCTGTGACA

12819 GTTCCTTCAATCTCTGCTG

12820 CGAGTTCCTTCAATCTCTGCTG 12821 GAGAGACGAGTTCCTTCA

12822 GGATAGAGAGACGAGTTC

12823 CTCCCATTGGATAGAGAGACG

12824 GTTTCTCCCATTGGATAGAG

12825 CACTGGTTTCTCCCATTGG 12826 GAATGCATTGGTCATCAA

12827 GAGATGAATGCATTGGTC

12828 CTTGAACATCGTACTTAG

12829 GCTCTCACTTGAACATCGTAC

12830 CTGCTCTCACTTGAACATCG 12831 CTGCTGCTCTCACTTGAAC

12832 TCTCTGCACATGGAGCTC

12833 CTGCCTCTCTGCACATGG

12834 GAGCCCTGCCTCTCTGCAC

12835 CTCCAGAGCCCTGCCTCTCT 12836 CTCACTCCAGAGCCCTGCC

12837 CTCCACTCACTCCAGAGCC

12838 TGGCTCCACTCACTCCAGAG

12839 GGTTGGCTCCACTCACTCCAG

12840 TGTTCATCATTTCCCACATA 12841 AAGGGCTTGTGTTCATCA

12842 AACCACTCTCTCAAGGGCT

12843 CAGTAACACTAATACCGT

12844 CAGATGGTTGCCATAATCAC

12845 TGAAGCAGATGGTTGCCAT 12846 CTCATAGTTAGTGGTTAC

12847 GCTTTCTCATAGTTAGTG

12848 GGACCCAGCTTTCTCATAG

12849 GACTTCAATTTCCGTCTC

12850 CAGATGACTTCAATTTCCG 12851 CAACTCCAGGCTTCTCTATA

12852 CAACTCCAGGCTTCTCTAT

12853 GGGTCTCAACTCCAGGCTTC

12854 CCAGGGTCTCAACTCCAGGC

12855 ATCCTCCAGGGTCTCAAC 12856 CACAGAATCCTCCAGGGT

12857 GGATGCCAAAGTGACAGTCA

12858 GGATGCCAAAGTGACAGTC

12859 TCATCAGAGGATGCCAAAGT

12860 GTGTGAGTTCATCAGAGGAT 12861 GGCATGTGTGAGTTCATCAG 12862 CTGAGGCATGTGTGAGTTC

12863 GAGCCAGCATCCCTGTTCTT

12864 GAGCCAGCATCCCCTGTTC

12865 AGCCAAGAGCCAGCATCCCTGT 12866 GCCAAGAGCCAGCATCCCTGT

12867 TAGCCAAGAGCCAGCATCCC

12868 CCTCTTAGCCAAGAGCCAGC

12869 ACACCTCTTAGCCAAGAGCC

12870 TCTGAACACCTCTTAGCCAAG 12871 TTCTGAACACCTCTTAGC

12872 CTGGGTGTATTGCTTCGCAG

12873 GGATGAAGCATCCATACTTT

12874 TGAGGCGATTTGGATGAAGC

12875 GTCAACTTCCCTGCTGTAGG 12876 TGCTTGGATGAGTCAACTTC

12877 GTGCTACCCTGTACGGCATG

12878 TTGGCAGGTGAGGAGGTGCT

12879 GTCTGAGGTGAGTCAAGC

12880 ACGGCACAGCCAGAAGTA 12881 ACAGCCAAACGGCACAGCCAG

12882 GTGCTACAATTGGCAGCTT

12883 TGGTTCACTCCAGGCTGATG

12884 CAGTCTTGAATCCAAGTTC CCR3 12885 TTTTAGAGGTGAGTGTGGAA

12886 GAGGTGAGTGTGGAAGGCTT

12887 AATGTGTTTGCTTCATCTCC

12888 GTTTGCTTCATCTCCTTGGT

12889 CTTCATCTCCTTGGTCCTTC 12890 TCTCCTTGGTCCTTCCTCTT

12891 TTGGTCCTTCCTCTTTAGGC

12892 CCTTCCTCTTTAGGCAATTT

12893 CTCTTTAGGCAATTTTCTGC

12894 TAGGCAATTTTCTGCATCTG 12895 AATTTTCTGCATCTGACCTA

12896 CAATAGAGAGTTCCGGCTCT

12897 GAGAGTTCCGGCTCTGCTGT

12898 TTCCGGCTCTGCTGTGGATG

12899 GCTCTGCTGTGGATGGAGAG 12900 GCTGTGGATGGAGAGACAGA

12901 GGATGGAGAGACAGAGCTGG

12902 GAGAGACAGAGCTGGTTCTT

12903 ACAGAGCTGGTTCTTTCCAG

12904 GCTGGTTCTTTCCAGCTTCT 12905 TTCTTTCCAGCTTCTCACTA

12906 TCCAGCTTCTCACTAGGAAG

12907 CTTCTCACTAGGAAGGAATG

12908 CACTAGGAAGGAATGGGATG

12909 GGAAGGAATGGGATGTATCT 12910 GAATGGGATGTATCTGCCCA

12911 GGATGTATCTGCCCAGGTGC

12912 TATCTGCCCAGGTGCATGAG

12913 GCCCAGGTGCATGAGCAAGT

12914 GGTGCATGAGCAAGTGCCTG 12915 ATGAGCAAGTGCCTGTGGAA

12916 CAAGTGCCTGTGGAAGAAGT

12917 GCCTGTGGAAGAAGTGGCGC

12918 TGGAAGAAGTGGCGCAGGTA

12919 GAAGTGGCGCAGGTACTTCC 12920 GGCGCAGGTACTTCCGGAAC

12921 AGGTACTTCCGGAACCTCTC

12922 CTTCCGGAACCTCTCTCCAA

12923 GCGTAGATCACCGGGTTCAT

12924 GATCACCGGGTTCATGCAGC 12925 CCGGGTTCATGCAGCAGTGG

12926 TTCATGCAGCAGTGGGAGTA

12927 GCAGCAGTGGGAGTAGGCGA

12928 AGTGGGAGTAGGCGATCACC

12929 GAGTAGGCGATCACCTCTGT 12930 GGCGATCACCTCTGTCACCA

12931 TCACCTCTGTCACCAGCATG

12932 TCTGTCACCAGCATGACCAG

12933 CACCAGCATGACCAGGTCCA

12934 GCATGACCAGGTCCAGATGC 12935 ACCAGGTCCAGATGCTTGCT 12936 GTCCAGATGCTTGCTCCGCT

12937 GATGCTTGCTCCGCTCACAG

12938 TTGCTCCGCTCACAGTCATT

12939 CCGCTCACAGTCATTTCCAA 12940 ATGGATTGATAGGAAGAGAG

12941 TTGATAGGAAGAGAGAAGGA

12942 AGGAAGAGAGAAGGATAGCC

12943 GAGAGAAGGATAGCCACATT

12944 AAGGATAGCCACATTGTAGG 12945 TAGCCACATTGTAGGGTGTC

12946 ACATTGTAGGGTGTCCAGAA

12947 GAGCCGGATGGCCTTGTACT

12948 GGATGGCCTTGTACTTTTTT

12949 GCCTTGTACTTTTTTTTACT 12950 ACCTCAGCAGCGTTTTGATG

12951 AGCAGCGTTTTGATGATTCC

12952 CGTTTTGATGATTCCTGTGT

12953 TGATGATTCCTGTGTAGCAG

12954 ATTCCTGTGTAGCAGATGGC 12955 CGAGCAGAGGGAGAACGAGA

12956 AGGTAGATGNTGGTCAT

12957 GGTCNGAAATGGCCAGGTT

12958 AGGAAGAGCAGGTCNGAAAT

12959 GTNATAAAACCCAGAGAGGA 12960 CCTGTGTNATAAAACCCAGA

12961 ACAAGCCTGTGTNATAAAAC

12962 GCTGTACAAGCCTGTGTNAT

12963 CTCGCTGTACAAGCCTGTGT

12964 AAGATCTCGCTGTACAAGCC 12965 AAAGAGGCTTGTACAGCGAG

12966 ATGAAAAAGATCTCGCTGT

12967 AGGATNATGAAAAAGATCTC

12968 CAGCAGGATNATGAAAAAGC

12969 ATCGTCAGCAGGATNATGAA 12970 GTCAATCGTCAGCAGGATNA

12971 ACCTGTCAATCGTCAGCAGG

12972 AGGTACCTGTCAATCGTCAG

12973 GGCCAGGTACCTGTCAATCG

12974 CNATCGATTGACAGGTACCT 12975 TGGACNATCGATTGACAGGT

12976 GTGATGACACCAAAAGTGAC

12977 GCTGGTGATGACACCAAAAG

12978 GATGCTGGTGATGACACCA

12979 CTGTACAAGCCTGTGNGA 12980 ATNCCTGTGTAGCAGATG

12981 GTAGGCGATCACCTCNGTCAC

12982 AAGGCGTAGATCACNGGGTT

12983 CCAACNAAGGCGTAGATCAC

12984 GTTGGAGAGAGGTTCCGGAA 12985 GAGAGAGGTTCCGGAAGTAC

12986 CGCAGGTACTTCCGGAACCTC

12987 TGNCGCAGGTACTTCCGGAA

12988 AGAGGGAGAACGAGACAGAA

12989 GAGAACGAGACAGAAGATGG 12990 CGAGACAGAAGATGGTCATT

12991 CAGAAGATGGTCATTCTCAG

12992 GATGGTCATTCTCAGAGTGT

12993 AACTCTTCAGTCTCATAGAA

12994 ATTCAGGAAGAGCTGCTAGC 12995 CAGGCCCCAGGTGACGATGC

12996 CCCAGGTGACGATGCTGGTG

12997 GTGACGATGCTGGTGATGAC

12998 AAGTGACAGTCCGGGCTCGA

12999 ACAGTCCGGGCTCGAAGGGC 13000 CAGCATGGACAATGGCCAGG

13001 TGGACAATGGCCAGGTACCT

13002 AATGGCCAGGTACCTGTCGA

13003 CCAGGTACCTGTCGATTGTC

13004 TACCTGTCGATTGTCAGCAG 13005 GTCGATTGTCAGCAGGATTA

13006 AAGATCTCGCTGTACAAGCC

13007 CTCGCTGTACAAGCCTGTGT

13008 AACCCTGAGAGGAGCTTACA

13009 TGAGAGGAGCTTACACATGC 13010 GGAGCTTACACATGCCATGG 13011 AACCCAGTTATGCCCCCTGA

13012 AGTTATGCCCCCTGACATAG

13013 TGCCCCCTGACATAGTGGAT

13014 CCTGACATAGTGGATCCAGA 13015 CATAGTGGATCCAGAATGGA

13016 TGGATCCAGAATGGAAGGGT

13017 CCAGAATGGAAGGGTGACGA

13018 ATGGAAGGGTGACGAGGAAG

13019 AGGGTGACGAGGAAGAGCAG 13020 GACGAGGAAGAGCAGGTCCG

13021 GCCAGGTTGAGCAGGTAGAT

13022 GTTGAGCAGGTAGATGTTGG

13023 GCAGGTAGATGTTGGTCATA

13024 ATTCGGAGCCTCCTGTATTT 13025 GAGCCTCCTGTATTTTATGA

13026 TCCTGTATTTTATGAGGATC .

13027 TATTTTATGAGGATCATCAC

13028 TATGAGGATCATCACCACCA

13029 GGATCATCACCACCACCACA 13030 ATCACCACCACCACATTGCC

13031 CACCACCACATTGCCCAAGA

13032 CCACATTGCCCAAGAGGCCC

13033 TTGCCCAAGAGGCCCACAGT

13034 CAAGAGGCCCACAGTGAACA 13035 GGCCCACAGTGAACACCAGG

13036 ACAGTGAACACCAGGGAGTA

13037 GAACACCAGGGAGTACAGCG

13038 CTGGGCCATCAGTGCTCTGG

13039 CCATCAGTGCTCTGGTATCA 13040 AGTGCTCTGGTATCAGCTTT

13041 TCTGGTATCAGCTTTTTCAC

13042 TATCAGCTTTTTCACAGAGC

13043 GCTTTTTCACAGAGCAGGCC

13044 TTCACAGAGCAGGCCCACGT 13045 AGAGCAGGCCCACGTCATCA

13046 AGGCCCACGTCATCATAGTA

13047 CACGTCATCATAGTAGGATG

13048 CATCATAGTAGGATGTGGTA

13049 GTATCTAGTGAGGTTGTCAT 13050 TAGTGAGGTTGTCATTTCAC

13051 AGGTTGTCATTTCACTTCTC

13052 GTCATTTCACTTCTCCCTGT

13053 TTCACTTCTCCCTGTGATA

13054 TTCTCCCTGTGATAGAAGAA 13055 TTCACTTCTCCCTGTGATAG

13056 TTCTCCCTGTGATAGAAGAA eotaxin

13057 GGTGGTGGTTTCTGGGTTGGT

13058 GGTGGTGGTTTCTGGGTTG 13059 TGTTGGAGGCTGAAGGTGTG

13060 CTGCGGAGACCTTCATGTTGG

13061 TGCTGCGGAGACCTTCATG

13062 GTGCTGCGGAGACCTTCATGT

13063 GGGCTGAAGGCAGCTGCT 13064 CTGGCCCAGCGAGCCCCTGG

13065 GCAGGTGGTTGGGACAGAAG

13066 TCTTCCTATTGGCCAGGTT

13067 CCTGTAGCTCTCTAGTCGCTG

13068 GGGACATTTGCCACTGGTG 13069 ATCACAGCTTTCTGGGGAC

13070 GGCCAGTTTGGTCTTGAAG

13071 CCTGCACCCACTTCTTCTTG

13072 TTGGTCCAGATACTTCATGG

13073 TATTTATGGCTTTGGAGTTG 13074 TCAGGCTCTGGTTTGGTTTC

13075 CCCATGCCCTTTGGACTG

13076 CTGATATTCATGGAGGAT

13077 TTGCCCACACGTGACAGGGG

13078 TGATCATCTTTGCCAGGACC 13079 GGGTTCACAAGAACAATGAC

13080 CTTCCATTTAATGAGTCACAC

13081 CCCCTCAGCTCAGTGTGG

13082 GGGCTTACCTGGCCAGC

13083 TGGTTACCTTACCTTTCCTG 13084 CTGACCTAGTAGCCTGGAGG 13085 GAATTTGCAGTGAGTCTGTA

13086 GAGGCATTTCTTGTCCACCC

13087 GGCTCTTCCAGTGACTGGAT

13088 GACTCGGGAGCTTTCTAGTT 13089 CCAGCGGCCCTCTTGAATGT

13090 CACTGTAAGGATAGCTGGGT

13091 CCATGCCCACAGTAAGACAG

13092 CAGATTTTCCTTCTCTCCCC

13093 TCTCTTAGCCACTGTCTCTG 13094 TCCCCTGGGACCTCGTTCTT

13095 TCTCCTAGATAACTTTCCC

13096 CAGAGTATGGGAAAATGAGT

13097 CTGGCTCAGTGGGACCGAT

13098 ^' TGTTTGTTACCATGCTATGC 13099 TGCAGAAGCCTGAGCCCATA

13100 CTCCATCAGTCTAGAATCCT

13101 TCCATCAATGTTCCCCCAC

13102 CCTGAGAGCTTTCTTCTGCT

13103 TGAGCCACAGTGCATTGCCT 13104 TCTTGGCCACTTTTGTTTGG

13105 GACTTGCATTTCTTGGCCAC

13106 TCTCCATCCTCTGTTTTGAG

13107 CGTGGCCATGTGATGGTC

13108 CATTACTGTAGAGTGTATGG 13109 TTGGAGGCATTAATTAGTTT

13110 GCATCCTCCCCTGTGCACTG

13111 GGATGCTGTCCTGTGTCTTC

13112 GGTGGAGGGAGAATCCCTCT

13113 GGTGGTTGGGACAGAAGCTG 13114 GGGTATCTTCCTATTGGCC

13115 TGATTCTCCTGTAGCTCTCT

13116 CACAGTTCTTGACTCTGTGC

13117 GGGAGCTGGGAGTGAACACT

13118 CCATCTTTGCTCTTGACTTG 13119 CTTGGGTTAGTTGCTGCTCT

13120 ACCCACTTCTTCTTGGGGTC

13121 TGGTCCAGATACTTCATGG

13122 CTCAGGCTCTGGTTTGGTTTC

13123 CCCATGCCCTTTGGACTG 13124 TAACTGATATTCATGGAGG

13125 TTGCCCACACGTGACAGGG

13126 GATTCCAGGGAGGAAGAG

13127 TACTGATCATCTTTGCCAGG

13128 TGAGTCACACTTTGGGTTC RANTES

13129 ATTTTTCATGTTTGCCAGTA

13130 GAGTGCAGTGTTCCTCCCTT

13131 CAGTGTTCCTCCCTTCCTTG

13132 TTCCTCCCTTCCTTGCCTCT 13133 CCCTTCCTTGCCTCTAGAGG

13134 CCTTGCCTCTAGAGGCATGC

13135 CCTCTAGAGGCATGCTGACT

13136 AGCAGCGCCTCAGAAGCTCT

13137 CGCCTCAGAAGCTCTTCTAG 13138 CAGAAGCTCTTCTAGGCTTT

13139 GCTCTTCTAGGCTTTAGTTG

13140 AGCCTCCACCTCCTGGGTTC

13141 CCTGCCTTAGCCTCCCGAGT

13142 CTTAGCCTCCCGAGTAGCTG 13143 CCTCCCGAGTAGCTGGGATT

13144 GGATTACAGGCGTGGGCCAC

13145 ACAGGCGTGGGCCACCACGC

13146 CGTGGGCCACCACGCGGCTA

13147 GCAGTGGCGCGATCTCGGCT 13148 CAAGCTCCGCTCCCGGGTTC

13149 TCCGCTCCCGGGTTCACGCC

13150 CTCAGCCTCCCGAGTAGCTG

13151 CCTCCCGAGTAGCTGGGACT

13152 CGAGTAGCTGGGACTACAGG 13153 AGCTGGGACTACAGGCGCCC

13154 GGACTACAGGCGCCCGCTAC

13155 CGCCCGCTACCACGCCCGGC

13156 TTTTGTATTTTTAGTACACA

13157 TTTCATCATGTTGGCCAGGC 13158 TGTCTCGAACTCCTGACCTC 13085 GAATTTGCAGTGAGTCTGTA

13086 GAGGCATTTCTTGTCCACCC

13087 GGCTCTTCCAGTGACTGGAT

13088 GACTCGGGAGCTTTCTAGTT 13089 CCAGCGGCCCTCTTGAATGT

13090 CACTGTAAGGATAGCTGGGT

13091 CCATGCCCACAGTAAGACAG

13092 CAGATTTTCCTTCTCTCCCC

13093 TCTCTTAGCCACTGTCTCTG 13094 TCCCCTGGGACCTCGTTCTT

13095 TCTCCTAGATAACTTTCCC

13096 CAGAGTATGGGAAAATGAGT

13097 CTGGCTCAGTGGGACCGAT

13098 TGTTTGTTACCATGCTATGC 13099 TGCAGAAGCCTGAGCCCATA

13100 CTCCATCAGTCTAGAATCCT

13101 TCCATCAATGTTCCCCCAC

13102 CCTGAGAGCTTTCTTCTGCT

13103 TGAGCCACAGTGCATTGCCT 13104 TCTTGGCCACTTTTGTTTGG

13105 GACTTGCATTTCTTGGCCAC

13106 TCTCCATCCTCTGTTTTGAG

13107 CGTGGCCATGTGATGGTC

13108 CATTACTGTAGAGTGTATGG 13109 TTGGAGGCATTAATTAGTTT

13110 GCATCCTCCCCTGTGCACTG

13111 GGATGCTGTCCTGTGTCTTC

13112 GGTGGAGGGAGAATCCCTCT

13113 GGTGGTTGGGACAGAAGCTG 13114 GGGTATCTTCCTATTGGCC

13115 TGATTCTCCTGTAGCTCTCT

13116 CACAGTTCTTGACTCTGTGC

13117 GGGAGCTGGGAGTGAACACT

13118 CCATCTTTGCTCTTGACTTG 13119 CTTGGGTTAGTTGCTGCTCT

13120 ACCCACTTCTTCTTGGGGTC

13121 TGGTCCAGATACTTCATGG

13122 CTCAGGCTCTGGTTTGGTTTC

13123 CCCATGCCCTTTGGACTG 13124 TAACTGATATTCATGGAGG

13125 TTGCCCACACGTGACAGGG

13126 GATTCCAGGGAGGAAGAG

13127 TACTGATCATCTTTGCCAGG

13128 TGAGTCACACTTTGGGTTC RANTES

13129 ATTTTTCATGTTTGCCAGTA

13130 GAGTGCAGTGTTCCTCCCTT

13131 CAGTGTTCCTCCCTTCCTTG

13132 TTCCTCCCTTCCTTGCCTCT 13133 CCCTTCCTTGCCTCTAGAGG

13134 CCTTGCCTCTAGAGGCATGC

13135 CCTCTAGAGGCATGCTGACT

13136 AGCAGCGCCTCAGAAGCTCT

13137 CGCCTCAGAAGCTCTTCTAG 13138 CAGAAGCTCTTCTAGGCTTT

13139 GCTCTTCTAGGCTTTAGTTG

13140 AGCCTCCACCTCCTGGGTTC

13141 CCTGCCTTAGCCTCCCGAGT

13142 CTTAGCCTCCCGAGTAGCTG 13143 CCTCCCGAGTAGCTGGGATT

13144 GGATTACAGGCGTGGGCCAC

13145 ACAGGCGTGGGCCACCACGC

13146 CGTGGGCCACCACGCGGCTA

13147 GCAGTGGCGCGATCTCGGCT 13148 CAAGCTCCGCTCCCGGGTTC

13149 TCCGCTCCCGGGTTCACGCC

13150 CTCAGCCTCCCGAGTAGCTG

13151 CCTCCCGAGTAGCTGGGACT

13152 CGAGTAGCTGGGACTACAGG 13153 AGCTGGGACTACAGGCGCCC

13154 GGACTACAGGCGCCCGCTAC

13155 CGCCCGCTACCACGCCCGGC

13156 TTTTGTATTTTTAGTACACA

13157 TTTCATCATGTTGGCCAGGC 13158 TGTCTCGAACTCCTGACCTC

700 13159 CGAACTCCTGACCTCAAGTG

13160 ACCTCAAGTGATCCACCCAC

13161 AAGTGATCCACCCACCTTGG

13162 ATCCACCCACCTTGGCCTCC 13163 TGCTGGGATTACAAGGCTGA

13164 GGATTACAAGGCTGAGCCAC

13165 ACAAGGCTGAGCCACCACGT

13166 GCCACCACGTCCAGCCTGGG

13167 TGCTGCTCGTCGTGGTCAGA 13168 CTCGTCGTGGTCAGAATCTG

13169 TCAGAATCTGGGCCCTTCAA

13170 ATCTGGGCCCTTCAAGGAGC

13171 GGCCCTTCAAGGAGCGGGTG

13172 GGGAAGCCTCCCAAGCTAGG 13173 GGCAGATGCAGGAGCGCAGA

13174 ATGCAGGAGCGCAGAGGGCA

13175 TCTCCATCCTAGCTCATCTC

13176 AGTTGATGTACTCCCGAACC

13177 GAACCCATTTCTTCTCTGGG 13178 CATTTCTTCTCTGGGTTGGC

13179 CTTCTCTGGGTTGGCACACA

13180 TTGGCACACACTTGGCGGTT

13181 ACACACTTGGCGGTTCTTTC

13182 CTTGGCGGTTCTTTCGGGTG 13183 CTGCTGGGTTGGAGCACTTG

13184 GGGTTGGAGCACTTGCCACT

13185 TACTCCTTGATGTGGGCACG

13186 GCTGAGCCACCACGTCCAGC

13187 CTGGGTTGGCACACACTTGG 13188 TCCTGACCTCAAGTGATCCA

13189 CGTGGTCAGAATCTGGGCCC

13190 ATTTTCCTGCCTTAGCCTCC

13191 GCCTCCCAAGCTAGGACAAG

13192 CCAAGCTAGGACAAGAGCAA 13193 CTAGGACAAGAGCAAGCAGA

13194 TTCAGGTTCAAGGACTCTCC

13195 GTTCAAGGACTCTCCATCCT

13196 AGGACTCTCCATCCTAGCTC

13197 ACAGGCGCCCGCTACCACGC 13198 ATGTACTCCCGAACCCATTT

13199 CTCCCGAACCCATTTCTTCT

13200 TCATGTTGGCCAGGCTGTCT

13201 TTGGCCAGGCTGTCTCGAAC

13202 CAGGCTGTCTCGAACTCCTG 13203 TCCCGGGTTCACGCCATTCT

13204 GGTTCACGCCATTCTCCTGC

13205 ACGCCATTCTCCTGCCTCAG

13206 ATTCTCCTGCCTCAGCCTCC

13207 CCTGCCTCAGCCTCCCGAGT 13208 GGGCAGTGGGCGGGCAATGT

13209 GTGGGCGGGCAATGTAGGCA

13210 AAGCAGCAGGGTGTGGTGTC

13211 GCAGGGTGTGGTGTCCGAGG

13212 GTGTGGTGTCCGAGGAATAT 13213 GGAGCGCAGAGGGCAGTAGC

13214 GCAGAGGGCAGTAGCAATGA

13215 GGGCAGTAGCAATGAGGATG

13216 GTAGCAATGAGGATGACAGC

13217 AATGAGGATGACAGCGAGGC 13218 GGATGACAGCGAGGCGTGCC

13219 ACAGCGAGGCGTGCCGCGGA

13220 GAGGCGTGCCGCGGAGACCT

13221 GTGCCGCGGAGACCTTCATG

13222 GCGGAGACCTTCATGGTACC 13223 GACCTTCATGGTACCTGTGG

13224 TCATGGTACCTGTGGAGAGG

13225 GTACCTGTGGAGAGGCTGTC

13226 TGTGGAGAGGCTGTCGGAGG

13227 AGAGGCATGCTGACTTCCTT 13228 CATGCTGACTTCCTTCCTTG

13229 TGACTTCCTTCCTTGTCACA

13230 TCCTTCCTTGTCACAGAGCC

13231 CCTTGTCACAGAGCCCTTGC

13232 CCAGAGCTCAGAACCTAGAG 13233 GCTCAGAACCTAGAGACTTC

701 13234 GAACCTAGAGACTTCCTTTT

13235 TAGAGACTTCCTTTTGACAA

13236 GGGAAGCTTTTTGTTGTTGT

13237 GCTTTTTGTTGTTGTTGTTG 13238 TTGTTGTTGTTGTTGTGACG

13239 GTTGTTGTTGTGACGGAGTC

13240 TGTTGTGACGGAGTCTCACT

13241 TGACGGAGTCTCACTTTGTC

13242 GAGTCTCACTTTGTCACCCA 13243 TCACTTTGTCACCCAGGCTG

13244 TTGTCACCCAGGCTGGAGTG

13245 ACCCAGGCTGGAGTGAAGTG

13246 GGCTGGAGTGAAGTGGCACA

13247 GAGTGAAGTGGCACAATCTC 13248 AAGTGGCACAATCTCAGCTC

13249 CGAGTAGCTGGGATTACAGG

13250 AGCTGGGATTACAGGCGTGG

13251 GAGACGGAGTCTCGCTCTGT

13252 GGAGTCTCGCTCTGTCGCCC 13253 CTCGCTCTGTCGCCCAGGCT

13254 TCTGTCGCCCAGGCTGGAGT

13255 CGCCCAGGCTGGAGTGCAGT

13256 AGGCTGGAGTGCAGTGGCGC

13257 GGAGTGCAGTGGCGCGATCT MCP4

13258 TCTGGCTGAGCAAGTCCCTG

13259 TGCATTCATCTTTCCACAAT

13260 AGAGCTCTCCTTCCTACATT

13261 TTCCTACATTGCGGCATCCC 13262 ACATTGCGGCATCCCTTCAT

13263 GCGGCATCCCTTCATGTCCA

13264 ATCCCTTCATGTCCATGACT

13265 TTCATGTCCATGACTCCCAC

13266 GTCCATGACTCCCACAGGCA 13267 TGACTCCCACAGGCATGCTC

13268 CCCACAGGCATGCTCTCAAC

13269 AGGCATGCTCTCAACCCCTG

13270 TGCTCTCAACCCCTGGGAAC

13271 TGCCAGCAGCTCATAGTGGA 13272 ATAGAAGAGGAGGCCAGAGG

13273 AGAGGAGGCCAGAGGAGAAT

13274 AGTCATTTCACGTACTCCAG

13275 TTTCACGTACTCCAGCTTGA

13276 CGTACTCCAGCTTGATTTCA 13277 ATTCTGGACCCACTTCTCCT

13278 GGACCCACTTCTCCTTTGGG

13279 GGTGATCACATAGCTCTTCA

13280 TCACATAGCTCTTCAGCCTC

13281 TAGCTCTTCAGCCTCTGCAA 13282 CTTCAGCCTCTGCAAGGAGA

13283 GCCTCTGCAAGGAGATCTTC

13284 ACCTGCTGGTGGTGATCACA

13285 CTGGTGGTGATCACATAGCT

13286 TCCAGCTTGATTTCAGTAGG 13287 GGTAGCAGAGTTCAAGTCTT

13288 CAGAGTTCAAGTCTTCAGGG

13289 TTCAAGTCTTCAGGGTGTGA

13290 GTCTTCAGGGTGTGAGCTTC

13291 CAGGGTGTGAGCTTCCGGCC 13292 TGTGAGCTTCCGGCCCAGGT

13293 GCTTCCGGCCCAGGTGTTTC

13294 CGGCCCAGGTGTTTCATATA

13295 GCAGCTCATAGTGGAAGGGA

13296 GCTTAGAGACAGCAACCTAC 13297 GAGACAGCAACCTACTTGCT

13298 AGCAACCTACTTGCTCAAGG

13299 CCTACTTGCTCAAGGCCTTG

13300 TTGCTCAAGGCCTTGCTATA

13301 ACATAGTACATTTTGAATCA 13302 CCGAATGCATCCTATTTGAA

13303 AATTATGGTAGAAGTATTCC

13304 TGGTTCTGAAGATGACAGCC

13305 CTGAAGATGACAGCCTTCTG

13306 GGGACACCTGCTGGTGGTGA 13307 TCAACCCCTGGGAACCGAAT

702 13308 TCTCCTTCCTACATTGCGGC

13309 AATGTCAGCAGTCCTACTAT

13310 CAGCAGTCCTACTATTGCAT

13311 GTCCTACTATTGCATTCATC 13312 ACTATTGCATTCATCTTTCC

13313 AACATATTTAGCAACACCTC

13314 ATTTAGCAACACCTCACATT

13315 GCAACACCTCACATTCACAA

13316 TGCAAGGAGATCTTCTTACT 13317 ATGTGAAGCAGCAAGTAGAT

13318 AAGCAGCAAGTAGATGGGAC

13319 GCAAGTAGATGGGACGTTGA

13320 TAGATGGGACGTTGAGTGCA

13321 GGGACGTTGAGTGCATCTGG 13322 GTTGAGTGCATCTGGCTGAG

13323 GTGCATCTGGCTGAGCAAGT

13324 CACTTCTCCTTTGGGTCAGC

13325 CTCCTTTGGGTCAGCACAGA

13326 TTGGGTCAGCACAGATCTCC 13327 TCAGCACAGATCTCCTTGCC

13328 ACAGATCTCCTTGCCCAGTT

13329 TCTCCTTGCCCAGTTTGGTT

13330 TTGCCCAGTTTGGTTCTGAA

13331 CAGTTTGGTTCTGAAGATGA 13332 TGGTTCTGAAGATGACAGCC

13333 CTGAAGATGACAGCCTTCTG

13334 GGGACACCTGCTGGTGGTGA

13335 ACCTGCTGGTGGTGATCACA

13336 CTGGTGGTGATCACATAGCT 13337 TCCAGCTTGATTTCAGTAGG

13338 GGTAGCAGAGTTCAAGTCTT

13339 CAGAGTTCAAGTCTTCAGGG

13340 TTCAAGTCTTCAGGGTGTGA

13341 GTCTTCAGGGTGTGAGCTTC 13342 CAGGGTGTGAGCTTCCGGCC

13343 TGTGAGCTTCCGGCCCAGGT

13344 GCTTCCGGCCCAGGTGTTTC

13345 CGGCCCAGGTGTTTCATATA

13346 GCAGCTCATAGTGGAAGGGA 13347 GCTTAGAGACAGCAACCTAC

13348 GAGACAGCAACCTACTTGCT

13349 AGCAACCTACTTGCTCAAGG

13350 CCTACTTGCTCAAGGCCTTG

13351 TTGCTCAAGGCCTTGCTATA 13352 ACATAGTACATTTTGAATCA

13353 CCGAATGCATCCTATTTGAA

13354 AATTATGGTAGAAGTATTCC

13355 TCAACCCCTGGGAACCGAAT

13356 TCTCCTTCCTACATTGCGGC 13357 AATGTCAGCAGTCCTACTAT

13358 CAGCAGTCCTACTATTGCAT

13359 GTCCTACTATTGCATTCATC

13360 ACTATTGCATTCATCTTTCC

13361 AACATATTTAGCAACACCTC 13362 ATTTAGCAACACCTCACATT

13363 GCAACACCTCACATTCACAA

13364 TGCAAGGAGATCTTCTTACT

13365 ATGTGAAGCAGCAAGTAGAT

13366 AAGCAGCAAGTAGATGGGAC 13367 GCAAGTAGATGGGACGTTGA

13368 TAGATGGGACGTTGAGTGCA

13369 GGGACGTTGAGTGCATCTGG

13370 GTTGAGTGCATCTGGCTGAG

13371 GTGCATCTGGCTGAGCAAGT 13372 CACTTCTCCTTTGGGTCAGC

13373 CTCCTTTGGGTCAGCACAGA

13374 TTGGGTCAGCACAGATCTCC

13375 TCAGCACAGATCTCCTTGCC

13376 ACAGATCTCCTTGCCCAGTT 13377 TCTCCTTGCCCAGTTTGGTT

13378 TTGCCCAGTTTGGTTCTGAA

13379 CAGTTTGGTTCTGAAGATGA CD23+A1261

13380 TGCGTCCCCGCTCCCTAGCTG 13381 TCCTGTTCTATTTGGCCTCTG

703 13382 GCTTGGAGGATTCATTATGCT

13383 GCCTGTGTCTGTCCTCCT

13384 GCTTCGTTCCTCTCGTTC

13385 CTGCTTGGTGCCCTTGCC 13386 GTCCTGCTCCTCCGGGCTGTG

13387 CCGGCTGGTGGGCTCCCCTGG

13388 GTCCTCGCCCTGGCTCCGGCT

13389 GCAGAAGGCGTCGTTCC

13390 CCTTCGCTGGCTGGCGGGGTC 13391 TCTTGCTCTGGGCCTGGCTGT

13392 GCTGCCTCCGTTTGGGTGGC

13393 GAAGCTCCTCGATCTCTG

13394 GGGAAGCTCCTCGATCTCTG

13395 CGCCTCCTGGGAAGCTCCTC 13396 CCTGCAACACCGCCTCCT

13397 CCTGCAACACCGCCTCCTGG

13398 GAGTCCCACGCCTGCAAC

13399 GAGTCCCACGCCTGCAACAC

13400 GATCTGAGTCCCACGCCTGC 13401 GCACGATCTGAGTCCCACGC

13402 AGCACGATCTGAGTCCCACGC

13403 CAGCCCCAGCAGCACGATCT

13404 GGTCACCAGCCCCAGCAGC

13405 CGGCGGTCACCAGCCCCAGC 13406 GCCCACAGAGCGGCGGTC

13407 CAGCAGCCCAGCCCACAG

13408 CAGAGTCAGCAGCCCAGCCC

13409 GAAGCAGAGTCAGCAGCCCAG

13410 CAGGAGAAGCAGAGTCAG 13411 TGCCACAGGAGAAGCAGA

13412 CCCAGTGCCACAGGAGAAGC

13413 GGTGTCCCAGTGCCACAGG

13414 TGTGTGGTGTCCCAGTGCCAC

13415 TGTGTGGTGTCCCAGTGCC 13416 TGTGTGGTGTCCCAGTGC

13417 GACTCTGTGTGGTGTCCCAGT

13418 GACTCTGTGTGGTGTCCC

13419 AGCTGTTTTAGACTCTGTGT

13420 CCTCTCTTCCAGCTGTTT 13421 GCAGCCCTCTCTTCCAGCTG

13422 TCCGGGCAGCCCTCTCTTCC

13423 TCCGGGCAGCCCTCTCTT

13424 GACGTTCCGGGCAGCCCTCTC

13425 GACGTTCCGGGCAGCCCTCT 13426 GACGTTCCGGGCAGCCCTC

13427 GACGTTCCGGGCAGCCCT

13428 TGAGAGACGTTCCGGGCAGCC

13429 CTTGAGAGACGTTCCGGGC

13430 CTTGGAAACTTGAGAGACG 13431 GTTCTTGGAAACTTGAGAG

13432 TTTCCAAGTTCTTGGAAACTT

13433 GTGGCTTTCCAAGTTCTTGG

13434 GTGGCTTTCCAAGTTCTT

13435 CCGTGGTGGCTTTCCAAGTTC 13436 CCGTGGTGGCTTTCCAAG

13437 GGTCACCGTGGTGGCTTTCC

13438 GGTCACCGTGGTGGCTTT

13439 CATCTGGTCACCGTGGTGGCT

13440 CATCTGGTCACCGTGGTG 13441 TGCGCCATCTGGTCACCGTGG

13442 TGCGCCATCTGGTCACCG

13443 TTTCTGCGCCATCTGGTCAC

13444 CTGGGATTTCTGCGCCATCTG

13445 CTGGGATTTCTGCGCCAT 13446 GTGGACTGGGATTTCTGCGCC

13447 GTGGACTGGGATTTCTGC

13448 TCTGCGTGGACTGGGATTTCT

13449 TCTGCGTGGACTGGGATT

13450 TGAAATCTGCGTGGACTGGG 13451 TCCTGTGAAATCTGCGTGG

13452 CCAGTTCCTGTGAAATCTGCG

13453 TTCCTCCAGTTCCTGTG

13454 CGAAGTTCCTCCAGTTCC

13455 CAGCTCGAAGTTCCTCCAGTT 13456 CTGTTCAGCTCGAAGTTCCTC

704 13457 CTCTGCTGTTCAGCTCGAAGT

13458 TCAATCTCTGCTGTTCAGCTC

13459 GATTTCAATCTCTGCTGTTC

13460 TCCTGAGATTTCAATCTCTGC 13461 CCAAGTCCTGAGATTTCAATC

13462 CAGCTCCAAGTCCTGAGATTT

13463 CAGGACAGCTCCAAGTCCTG

13464 GGTTCCAGGACAGCTCCAAGT

13465 GTTCAGGTTCCAGGACAGCTC 13466 GCCCGTTCAGGTTCCAGG

13467 CTTGAAGCCCGTTCAGGTTCC

13468 TCTGCTTGAAGCCCGTTCAGG

13469 CTCAGATCTGCTTGAAGCCCG

13470 GCTGCTCAGATCTGCTTG 13471 CTTGAAGCTGCTCAGATCTGC

13472 TGGGACTTGAAGCTGCTC

13473 TTCCTGGGACTTGAAGCTGCT

13474 GTTCAATTCCTGGGACTTG

13475 CTCCTCCCGGAGTCTTTCCAG 13476 GTCACCTCCTCCCGGAGTCTT

13477 GCTTTGTCACCTCCTCCCGG

13478 CCTTAGCTTTGTCACCTCCTC

13479 TCCATCCTTAGCTTTGTCACC

13480 GCAACTCCATCCTTAGCTTTG 13481 CACCTGCAACTCCATCCTT

13482 CTGGACACCTGCAACTCCATC

13483 GCCGCTGGACACCTGCAACTC

13484 CACAAAGCCGCTGGACACCTG

13485 TTGCACACAAAGCCGCTGG 13486 CGTGTTGCACACAAAGCCGCT

13487 CCACTTTTCAGGGCACGTGTT

13488 GTTGATCCACTTTTCAGGGC

13489 TGGAAGTTGATCCACTTTTC

13490 TCCGTTGGAAGTTGATCC 13491 GCACTTCCGTTGGAAGTTG

13492 TAGTAGCACTTCCGTTGG

13493 CGAAGTAGTAGCACTTCCG

13494 CTTGCCGAAGTAGTAGCACTT

13495 GTGCCCTTGCCGAAGTAGT 13496 TGGACCCACTGCTTGGTGCCC

13497 GGGCGTGGACCCACTGCT

13498 TACCGGGCGTGGACCCAC

13499 CAGGCATACCGGGCGTGG

13500 CGTCACAGGCATACCGGG 13501 CATGTCGTCACAGGCATACCG

13502 CCTTCCATGTCGTCACAGGC

13503 GCTGCCCTTCCATGTCGT

13504 GACCAGCTGCCCTTCCATGT

13505 TGCTGACCAGCTGCCCTTCC 13506 TGTGGATGCTGACCAGCTGC

13507 GCTTGGTCAGGAAGTCCTGC

13508 GGCATGCTTGGTCAGGAAGTC

13509 TGGCTGGCATGCTTGGTCAGG

13510 CGGTGTGGCTGGCATGCTTGG 13511 GGAGCCGGTGTGGCTGGC

13512 TCCAGGAGCCGGTGTGGCTGG

13513 GGCCAATCCAGGAGCCGGTGT

13514 CCGAAGGCCAATCCAGGAGCC

13515 GGTCCAAGTTCCGAAGGCC 13516 CTTCAGGTCCAAGTTCCG

13517 TCTCCCTTCAGGTCCAAGTTC

13518 TAAACTCTCCCTTCAGGTCC

13519 CCAGATAAACTCTCCCTTCAG

13520 TCCACCCAGATAAACTCTCCC 13521 TCCCATCCACCCAGATAAACT

13522 TGGCTCCCATCCACCCAGAT

13523 TGGCTCCCATCCACCCAG

13524 ATGGCTCCCATCCACCCAGAT

13525 TCCACATGGCTCCCATCCACC 13526 TCCACATGGCTCCCATCC

13527 TGTAGTCCACATGGCTCCCAT

13528 TGTAGTCCACATGGCTCCC

13529 GCCCAGTTGCTGTAGTCC

13530 CTGGAGCCCAGTTGCTGT 13531 CTCCCCTGGAGCCCAGTTGCT

705 13532 GGTCCAGCGACCGGAGCC

13533 GTCGCAGAAGGCGTCGGTCC

13534 TTACGGTCGCAGAAGGCGTC

13535 CCAGCTTACGGTCGCAGAAGG 13536 GGCGCCCAGCTTACGGTCGC

13537 CCCAGGCGCCCAGCTTACGGT

13538 CGCACACCCAGGCGCCC

13539 CCGGTCGCACACCCAGGCGC

13540 GCCAGCCGGTCGCACACC 13541 TGTGGCCAGCCGGTCGCAC

13542 CGTGCATGTGGCCAGCCGGTC

13543 CGTGCATGTGGCCAGCCG

13544 TGGCTGGCGGCGTGCATGTG

13545 GGACTCCGCGGAACCTTCGC 13546 CCCATGGACTCCGCGGAACC

13547 CAGGTCCCATGGACTCCGCG

13548 TGAATCAGGTCCCATGGACTC

13549 TGAATCAGGTCCCATGGAC

13550 GGTCTTGAATCAGGTCCCATG 13551 GGTCTGGTCTTGAATCAGGTC

13552 GTCAGGGTCTGGTCTTGAATC

13553 GCAGGCGGCCGTCAGGGTC

13554 TCCATGCTCAAGAGTGGAGAG

13555 TCCATGCTCAAGAGTGGAG 13556 TGGGCCTGGCTGTATCCATGC

13557 GGTCTTCAGGGTCTTGCTCTG

13558 GGCTTTTAGGCCGTGGTTGG

13559 GCCACAAAGAGGCTTTTAGGC

13560 GGACCTTTCAGCCACAAAGAG 13561 TGTCACAGGGACCTTTCAGCC

13562 CAGAAAATGTCACAGGGACCT

13563 GGTGGCAGAAAATGTCACAGG

13564 GGTGGCAGAAAATGTCAC

13565 GTTTGGGTGGCAGAAAATGTC 13566 CCTCCGTTTGGGTGGCAG

13567 TGCCTCCGTTTGGGTGGC

13568 GTGTCAGCTGCCTCCGTTTGG

13569 GTGTCAGCTGCCTCCGTTT

13570 GTGTCAGCTGCCTCCGTT 13571 GCGGGAGATGTGTCAGCTGC

13572 GAGGAGCGGGAGATGTGTC

13573 GCCATAGAGGAGCGGGAG

13574 GTACTCCTGGGAAGGCAGGG

13575 GGAGAGGGTGCTGTTGGG 13576 TCTGGAGAGGGTGCTGTTGGG

13577 TCTGGAGAGGGTGCTGTTGG

13578 TCTGGAGAGGGTGCTGTTG

13579 TCTGGAGAGGGTGCTGTT

13580 TCTGGAGAGGGTGCTGT 13581 TCTGGAGAGGGTGCTG

13582 CATCTGGAGAGGGTGCTGTTG

13583 CATCTGGAGAGGGTGCTGT

13584 CATCTGGAGAGGGTGCT

13585 CATCTGGAGAGGGTG 13586 CTCCCATCTGGAGAGGGTGCT

13587 GGGCACTCCCATCTGGAGAGG

13588 GGGCACTCCCATCTGGAG

13589 CTCTCATCTGGAGAGGGTGC

13590 GAGGACTCACCACCCTGAGC 13591 GGCTGGACAGGAGGACTC

13592 TATTGATGCAGGCTGGACAGG

13593 GGCCATCACTGCCCCATTT VCAM

13594 TTTAGTACTGTGTCTCCTGT 13595 CTTTCTGCTTCTTCCAGCCT

13596 CTTCCAGCCTGGTTAATTCC

13597 TTTGCGTACTCTGCCTTTGT

13598 CTGCCTTTGTTTGGGTTCGA

13599 TGGTAGGGATGAAGGTCATT 13600 TGTTCTCTAGAGATTTCATA

13601 AGATTTCATATCCGTATCCT

13602 CCAAAAACTCTATATTCTCC

13603 TATATTCTCCAGAATAGTCT

13604 TAATTCAATCTCCAGCCGGT 13605 CACGCTAGGAACCTTGCAGC

706 13606 TTCACGAGGCCACCACTCAT

13607 CACCACTCATCTCGATTTCT

13608 CCGCTCAGAGGGCTGTCTAT

13609 GGCTGTCTATCTGGGTTCTC 13610 CTGGGTTCTCCAGGAGAAAG

13611 ATCTCAACAGTAAATGGTTT

13612 CCAGAATCTTCCATCCTCAT

13613 CAGCCTGCCTTACTGTGGGC

13614 TACTGTGGGCACAGAATCCA 13615 TTCACAAGTTGCTGTGCACA

13616 GCTGTGCACAGGTAAGAGTG

13617 TTCGTTCCCAAAACTAACAG

13618 TAGATTCTGGGGTGGTCTCG ICAM 13619 GGAAGTGTGGGCCTTTGTGT

13620 GCCTTTGTGTTTTGATGCTA

13621 TTTGATGCTACACATGTCTA

13622 CACATGTCTATGGAGGGCCA

13623 TGGAGGGCCACTTCTTCTGT 13624 CTTCTTCTGTAAGTCTGTGG

13625 AAGTCTGTGGGGCCTCAGCA

13626 GGCCTCAGCATACCCAATAG

13627 TACCCAATAGGCAGCAAGTT

13628 GCAGCAAGTTTCAGTATTTC 13629 TCAGTATTTCCCAGTTGTAT 13630 CCAGTTGTATGTCCTCATGG

13631 GTCCTCATGGTGGGGCTATG

13632 TGGGGCTATGTCTCCCCCAC

13633 TCTCCCCCACCACTTCCCCT 13634 CACTTCCCCTCTCATCAGGC

13635 CTCATCAGGCTAGACTTTAA

13636 TAGACTTTAACATCCATCAA

13637 CATCCATCAATCATGTCTTG

13638 TCATGTCTTGAGTCTTGCTC 13639 AGTCTTGCTCCTTCCTCTTG

13640 CTTCCTCTTGGCTTAGTCAT

13641 GCTTAGTCATGTGACTACAG

13642 GTGACTACAGATCAGATGCG

13643 ATCAGATGCGTGGCCTAGTG 13644 TGGCCTAGTGTTTTAGGTGT

13645 TTTTAGGTGTGCAGGTACCA

13646 GCAGGTACCATGGCCCCAAA

13647 TGGCCCCAAATGCTGTTGTA

13648 TGCTGTTGTATCTGACTGAG 13649 TCTGACTGAGGACAATGCCC

13650 GACAATGCCCTGTCCTCCGG

13651 TGTCCTCCGGCGTCCCAGGG

13652 CGTCCCAGGGCCGGTAGGTG

13653 CCGGTAGGTGTAGCTGCATG 13654 TAGCTGCATGGCATATGTCT

13655 GCATATGTCTTCCACTCTGT

13656 TCCACTCTGTTCAGTGTGGC

13657 TCAGTGTGGCACCACTGCCA

13658 ACCACTGCCACCAATATGGG 13659 CCAATATGGGAAGGCCGAGG

13660 AAGGCCGAGGAAGAGGCCCT

13661 AAGAGGCCCTGTCCCGGGAT

13662 GTCCCGGGATAGGTTCAGGG

13663 AGGTTCAGGGAGGCGTGGCT 13664 AGGCGTGGCTTGTGTGTTCG

13665 TGTGTGTTCGGTTTCATGGG

13666 GTTTCATGGGGGTCCCTTTT

13667 GGTCCCTTTTTGGGCCTGTT

13668 TGGGCCTGTTGTAGTCTGTA 13669 GTAGTCTGTATTTCTTGATC

13670 TTTCTTGATCTTCCGCTGGC

13671 TTCCGCTGGCGGTTATAGAG

13672 GGTTATAGAGGTACGTGCTG

13673 GTACGTGCTGAGGCCTGCAG 13674 AGGCCTGCAGTGCCCATTAT

13675 TGCCCATTATGACTGCGGCT

13676 GACTGCGGCTGCTACCACAG

13677 GCTACCACAGTGATGATGAC

13678 TGATGATGACAATCTCATAC 13679 AATCTCATACCGGGGGGAGA

707 13680 CGGGGGGAGAGCACATTCAC

13681 GCACATTCACGGTCACCTTG

13682 GGTCACCTTGCGGGTGACCT

13683 CGGGTGACCTCCCCTTGAGT 13684 CCCCTTGAGTGCTCCTGGCC

13685 GCTCCTGGCCCGACAGAGGT

13686 CGACAGAGGTAGGTGCCCTC

13687 AGGTGCCCTCAAGATCTCGA

13688 AAGATCTCGAGTGACAGTCA 13689 GTGACAGTCACTGATTCCCC

13690 CTGATTCCCCGATGGGCAGT

13691 GATGGGCAGTGGGAAAGTGC

13692 GGGAAAGTGCCATCCTTTAG

13693 CATCCTTTAGACACTTGAGC 13694 ACACTTGAGCTCGGGCAATG

13695 TCGGGCAATGGGTTCCCCCA

13696 GGTTCCCCCAAGCCTGGCAC

13697 AGCCTGGCACATTGGAGTCT

13698 ATTGGAGTCTGCTGGGAATT 13699 GCTGGGAATTTTCTGGCCAC

13700 TTCTGGCCACGTCCAGTTTC

13701 GTCCAGTTTCCCGGACAATC

13702 CCGGACAATCCCTCTCGTCC

13703 CCTCTCGTCCAGTCGGGGGC 13704 AGTCGGGGGCCATACAGGAC

13705 CATACAGGACACGAAGCTCC

13706 ACGAAGCTCCCGGGTCTGGT

13707 CGGGTCTGGTTCTTGTGTAT

13708 TCTTGTGTATAAGCTGGCCG 13709 AAGCTGGCCGGCCACCTCCA

13710 GCCACCTCCAGGGTTGCAGA

13711 GGGTTGCAGAGCAGGAGAAG

13712 GCAGGAGAAGCTGCGCCCGT

13713 CTGCGCCCGTTGTCCTCTGG 13714 TGTCCTCTGGGGTGGCCTTC

13715 GGTGGCCTTCAGCAGGAGCT

13716 AGCAGGAGCTGGGCCCTCGG

13717 GGGCCCTCGGGCCCAGTGGC

13718 GCCCAGTGGCTGGGCTGGAA 13719 TGGGCTGGAACCCCATTCAG

13720 CCCCATTCAGCGTCACCTTG

13721 CGTCACCTTGGCTCTAGGGT

13722 GCTCTAGGGTGGGCCTCACA

13723 GGGCCTCACACTTCACTGTC 13724 CTTCACTGTCACCTCGGTCC

13725 ACCTCGGTCCCTTCTGAGAC

13726 CTTCTGAGACCTCTGGCTTC

13727 CTCTGGCTTCGTCAGAATCA

13728 GTCAGAATCACGTTGGGCGC 13729 CGTTGGGCGCCGGAAAGCTG

13730 CGGAAAGCTGTAGATGGTCA

13731 TAGATGGTCACTGTCTGCAG

13732 CTGTCTGCAGTGTCTCCTGG

13733 TGTCTCCTGGCTCTGGTTCC 13734 CTCTGGTTCCCCAGTATTAC

13735 CCAGTATTACTGCACACGTC

13736 TGCACACGTCAGCCGCTGGG

13737 AGCCGCTGGGTGCCCTCGTC

13738 TGCCCTCGTCCTCTGCGGTC 13739 CTCTGCGGTCACACTGACTG

13740 ACACTGACTGAGGCCTTGGC

13741 AGGCCTTGGCCGAGAAGGAG

13742 CGAGAAGGAGTCGTTGCCAT

13743 TCGTTGCCATAGGTGACTGT 13744 AGGTGACTGTGGGGTTCAAC

13745 GGGGTTCAACCTCTGGTCCC

13746 CTCTGGTCCCCCAGTGCCAG

13747 CCAGTGCCAGGTGGACCTGG

13748 GTGGACCTGGGCCTCCGAGA 13749 GCCTCCGAGACTGGGAACAG

13750 CTGGGAACAGCCCGTCCAGG

13751 CCCGTCCAGGGAACAGACCA

13752 GAACAGACCACGGTCCCCTG

13753 CGGTCCCCTGCGTGTCCACC 13754 CGTGTCCACCTCTAGGACCC

708 13755 TCTAGGACCCGGGGGCTGAC

13756 GGGGGCTGACAAGTTGTGGG

13757 AAGTTGTGGGGGAGTCGCTG

13758 GGAGTCGCTGGCAGGACAAA 13759 GCAGGACAAAGGTCTGGAGC

13760 GGTCTGGAGCTGGTAGGGGG

13761 TGGTAGGGGGCCGAGGTGTT

13762 CCGAGGTGTTCTCAAACAGC

13763 CTCAAACAGCTCCAGCCCTT 13764 TCCAGCCCTTGGGGCCGCAG

13765 GGGGCCGCAGGTCCAGTTCA

13766 GTCCAGTTCAGTGCGGCACG

13767 GTGCGGCACGAGAAATTGGC

13768 AGAAATTGGCTCCATGGTGA 13769 TCCATGGTGATCTCTCCTCA

13770 TCTCTCCTCACCAGCACCGT

13771 CCAGCACCGTGGTCGTGACC

13772 GGTCGTGACCTCAGCGGGCT

13773 TCAGCGGGCTCCCCCACAGC 13774 CCCCCACAGCTGGCTCCCGT

13775 TGGCTCCCGTTTCAGCTCCT

13776 TTCAGCTCCTTCTCCCCACG

13777 TCTCCCCACGGAGCAGCACC

13778 GAGCAGCACCACGGTGAGGT 13779 ACGGTGAGGTTGGCCCGGGG

13780 TGGCCCGGGGTGCCCCACCC

13781 TGCCCCACCCTCCACCTGGC

13782 TCCACCTGGCAGCGTAGGGT

13783 AGCGTAGGGTAAGGTTCTTG 13784 AAGGTTCTTGCCCACTGGCT

13785 CCCACTGGCTGCCAAGAGGG

13786 GCCAAGAGGGGAGGGGTGCC

13787 GAGGGGTGCCAGTTCCACCC

13788 AGTTCCACCCGTTCTGGAGT 13789 GTTCTGGAGTCCAGTACACG

13790 CCAGTACACGGTGAGGAAGG

13791 GTGAGGAAGGTTTTAGCTGT

13792 TTTTAGCTGTTGACTGCCCA

13793 TGACTGCCCATCAGGGCAGT 13794 TCAGGGCAGTTTGAATAGCA

13795 TTGAATAGCACATTGGTTGG

13796 CATTGGTTGGCTATCTTCTT

13797 CTATCTTCTTGCACATTGCT

13798 GCACATTGCTCAGTTCATAC 13799 CAGTTCATACACCTTCCGGT

13800 ACCTTCCGGTTGTTCCCAGG

13801 TGTTCCCAGGCAGGAGCAAC

13802 CAGGAGCAACTCCTTTTTAG

13803 TCCTTTTTAGGCAACGGGGT 13804 GCAACGGGGTCTCTATGCCC

13805 CTCTATGCCCAACAACTTGG

13806 AACAACTTGGGCTGGTCACA

13807 GCTGGTCACAGGAGGTGCTG

13808 GGAGGTGCTGCATGTCACCA 13809 CATGTCACCAGCACGGAGCC

13810 GCACGGAGCCTCCCCGGGGC

13811 TCCCCGGGGCAGGATGACTT

13812 AGGATGACTTTTGAGGGGGA

13813 TTGAGGGGGACACAGATGTC 13814 CACAGATGTCTGGGCATTGC

13815 TGGGCATTGCCAGGTCCTGG

13816 CAGGTCCTGGGAACAGAGCC

13817 GAACAGAGCCCCGAGCAGGA

13818 CCGAGCAGGACCAGGAGTGC 13819 CCAGGAGTGCGGGCAGCGCG

13820 GGGCAGCGCGGGCCGGGGGC

13821 GGCCGGGGGCTGCTGGGAGC

13822 TGCTGGGAGCCATAGCGAGG

13823 CATAGCGAGGCTGAGGTTGC 13824 CTGAGGTTGCAACTCTGAGT

13825 AACTCTGAGTAGCAGAGGAG

13826 AGCAGAGGAGCTCAGCGTCG

13827 CTCAGCGTCGACTGGGGCGC Tryptase a 13828 AGGCTCAGCATCCTGGCCAC

709 13829 GCAGCAGGCTCAGCATCCTG

13830 CAGCAGCAGCAGGCTCAGCA

13831 AGCGCCAGCAGCAGCAGGCT

13832 CGGGCAGCGCCAGCAGCAGC 13833 CAGGACGGGCAGCGCCAGCA

13834 CTCGCCAGGACGGGCAGCGC

13835 CGCGGCTCGCCAGGACGGGC

13836 GTAGGCGCGGCTCGCCAGGA

13837 GCCGCGTAGGCGCGGCTCGC 13838 CAGGGGCCGCGTAGGCGCGG

13839 TGGGGCAGGGGCCGCGTAGG

13840 TGGACTGGGGCAGGGGCCGC

13841 GGGCCTGGACTGGGGCAGGG

13842 CTGCAGGGCCTGGACTGGGG 13843 GCTTGCTGCAGGGCCTGGAC

13844 TACCCGCTTGCTGCAGGGCC

13845 GACGATACCCGCTTGCTGCA

13846 CCCCCGACGATACCCGCTTG

13847 CCTGACCCCCGACGATACCC 13848 GGCCTCCTGACCCCCGACGA

13849 CTGGGGGCCTCCTGACCCCC

13850 TGCTCCTGGGGGCCTCCTGA

13851 CCACTTGCTCCTGGGGGCCT

13852 CAGGGCCACTTGCTCCTGGG 13853 CCTGCCAGGGCCACTTGCTC

13854 GCTCACCTGCCAGGGCCACT

13855 CTCAGGCTCACCTGCCAGGG

13856 GGACTCTCAGGCTCACCTGC

13857 GTCGCGGACTCTCAGGCTCA 13858 TATCGGTCGCGGACTCTCAG

13859 TCCAGTATCGGTCGCGGACT

13860 GTGCATCCAGTATCGGTCGC

13861 CAGAAGTGCATCCAGTATCG

13862 CCCCGCAGAAGTGCATCCAG 13863 GGAGCCCCCGCAGAAGTGCA

13864 ATGAGGGAGCCCCCGCAGAA

13865 GGTGGATGAGGGAGCCCCCG

13866 CTGGGGGTGGATGAGGGAGC

13867 ACCCACTGGGGGTGGATGAG 13868 TCAGCACCCACTGGGGGTGG

13869 CGCGGTCAGCACCCACTGGG

13870 TGCGCCGCGGTCAGCACCCA

13871 GGCAGTGCGCCGCGGTCAGC

13872 TCCCAGGCAGTGCGCCGCGG 13873 TCCGGTCCCAGGCAGTGCGC

13874 TGACGTCCGGTCCCAGGCAG

13875 ATCCTTGACGTCCGGTCCCA

13876 GCCAGATCCTTGACGTCCGG

13877 GGGTGGCCAGATCCTTGACG 13878 CCTGAGGGTGGCCAGATCCT

13879 TGCACCCTGAGGGTGGCCAG

13880 GCAGTTGCACCCTGAGGGTG

13881 CTCCCGCAGTTGCACCCTGA

13882 TGCTGCTCCCGCAGTTGCAC 13883 AGAGGTGCTGCTCCCGCAGT

13884 GTAGTAGAGGTGCTGCTCCC

13885 TCCTGGTAGTAGAGGTGCTG

13886 GCTGGTCCTGGTAGTAGAGG

13887 CAGCAGCTGGTCCTGGTAGT 13888 ACTGGCAGCAGCTGGTCCTG

13889 TGCTGACTGGCAGCAGCTGG

13890 GATCCTGCTGACTGGCAGCA

13891 ACGATGATCCTGCTGACTGG

13892 GGTGCACGATGATCCTGCTG 13893 CTGTGGGTGCACGATGATCC

13894 TAGAACTGTGGGTGCACGAT

13895 TGATGTAGAACTGTGGGTGC

13896 CTGGATGATGTAGAACTGTG

13897 CCAGTCTGGATGATGTAGAA 13898 CCGCTCCAGTCTGGATGATG

13899 GATATCCGCTCCAGTCTGGA

13900 AGGGCGATATCCGCTCCAGT

13901 CCAGCAGGGCGATATCCGCT

13902 CAGCTCCAGCAGGGCGATAT 13903 TCCTCCAGCTCCAGCAGGGC

710 13904 CGGGCTCCTCCAGCTCCAGC

13905 GTTCACGGGCTCCTCCAGCT

13906 GAGATGTTCACGGGCTCCTC

13907 GGCTGGAGATGTTCACGGGC 13908 GACGCGGCTGGAGATGTTCA

13909 GTGTGGACGCGGCTGGAGAT

13910 TGACCGTGTGGACGCGGCTG

13911 CAGCATGACCGTGTGGACGC

13912 GGGGGCAGCATGACCGTGTG 13913 AGGCAGGGGGCAGCATGACC

13914 CTCCGAGGCAGGGGGCAGCA

13915 AAGGTCTCCGAGGCAGGGGG

13916 GGGGGAAGGTCTCCGAGGCA

13917 CCCCGGGGGGAAGGTCTCCG 13918 GGCATCCCCGGGGGGAAGGT

13919 AGCACGGCATCCCCGGGGGG

13920 GACCCAGCACGGCATCCCCG

13921 CCAGTGACCCAGCACGGCAT

13922 CCCAGCCAGTGACCCAGCAC 13923 ATCGCCCCAGCCAGTGACCC

13924 TCCACATCGCCCCAGCCAGT

13925 CATTGTCCACATCGCCCCAG

13926 CTCATCATTGTCCACATCGC

13927 AGGGGCTCATCATTGTCCAC 13928 GTGGGAGGGGCTCATCATTG

13929 TGGCGGTGGGAGGGGCTCAT

13930 GGAAATGGCGGTGGGAGGGG

13931 TCAGGGGAAATGGCGGTGGG

13932 CTGCTTCAGGGGAAATGGCG 13933 TTCACCTGCTTCAGGGGAAA

13934 GGACCTTCACCTGCTTCAGG

13935 TATGGGGACCTTCACCTGCT

13936 TCCATTATGGGGACCTTCAC

13937 GGTTTTCCATTATGGGGACC 13938 AATGTGGTTTTCCATTATGG

13939 TCACAAATGTGGTTTTCCAT

13940 TTGCGTCACAAATGTGGTTT

13941 GTATTTTGCGTCACAAATGT

13942 AGGTGGTATTTTGCGTCACA 13943 CGCCAAGGTGGTATTTTGCG

13944 GTAGGCGCCAAGGTGGTATT

13945 CCCGTGTAGGCGCCAAGGTG

13946 CGTCTCCCGTGTAGGCGCCA

13947 GACGTCGTCTCCCGTGTAGG 13948 ATGCGGACGTCGTCTCCCGT

13949 GGATGATGCGGACGTCGTCT

13950 GTCACGGATGATGCGGACGT

13951 ATGTCGTCACGGATGATGCG

13952 ACAGCATGTCGTCACGGATG 13953 GGCACACAGCATGTCGTCAC

13954 TTCCCGGCACACAGCATGTC

13955 GGCTGTTCCCGGCACACAGC

13956 CCTCTGGCTGTTCCCGGCAC

13957 GAGTCCCTCTGGCTGTTCCC 13958 TGCAGGAGTCCCTCTGGCTG

13959 GCCCTTGCAGGAGTCCCTCT

13960 GAGTCGCCCTTGCAGGAGTC

13961 CTCCAGAGTCGCCCTTGCAG

13962 GGGCCCTCCAGAGTCGCCCT 13963 ACCAGGGGCCCTCCAGAGTC

13964 TGCACACCAGGGGCCCTCCA

13965 CACCTTGCACACCAGGGGCC

13966 CCATTCACCTTGCACACCAG

13967 AGGTGCCATTCACCTTGCAC 13968 TAGCCAGGTGCCATTCACCT

13969 GCCTGTAGCCAGGTGCCATT

13970 CGCCCGCCTGTAGCCAGGTG

13971 GACCACGCCCGCCTGTAGCC

13972 CAGCTGACCACGCCCGCCTG 13973 CGTCCCAGCTGACCACGCCC

13974 GCCCTCGTCCCAGCTGACCA

13975 GCACAGCCCTCGTCCCAGCT

13976 GCTGGGCACAGCCCTCGTCC

13977 GTTGGGCTGGGCACAGCCCT 13978 GGCCGGTTGGGCTGGGCACA

711 13979 TGCCAGGCCGGTTGGGCTGG

13980 GTAGATGCCAGGCCGGTTGG

13981 CGGGTGTAGATGCCAGGCCG

13982 TGACACGGGTGTAGATGCCA 13983 GTAGGTGACACGGGTGTAGA

13984 AAGTAGTAGGTGACACGGGT

13985 AGTCCAAGTAGTAGGTGACA

13986 GATCCAGTCCAAGTAGTAGG

13987 TGGTGGATCCAGTCCAAGTA 13988 CATAGTGGTGGATCCAGTCC

13989 GGGGACATAGTGGTGGATCC

13990 TTTTTGGGGACATAGTGGTG

13991 ACGGCTTTTTGGGGACATAG

13992 GACTCACGGCTTTTTGGGGA Tryptase b

13993 AGATTCAGCATCCTGGCCAC

13994 GCAGCAGATTCAGCATCCTG

13995 CAGCAGCAGCAGATTCAGCA

13996 AGCGCCAGCAGCAGCAGATT 13997 TGGCCTGGGGCAGGGGCCGC

13998 GGGCCTGGACTGGGGCAGGG

13999 CTGCAGGGCCTGGCCTGGGG

14000 CCTCGCTGCAGGGCCTGGCC

14001 TGCCCACTCGCTGCAGGGCC 14002 AACGATGCCCACTCGCTGCA

14003 CCCCCAACGATGCCCACTCG

14004 CCTGACCCCCAACGATGCCC

14005 GGCCTCCTGACCCCCAACGA

14006 GCCGTGGACTCTCAGGCTCA 14007 TATGGGCCGTGGACTCTCAG

14008 TCCAGTATGGGCCGTGGACT

14009 GTGCATCCAGTATGGGCCGT

14010 CAGAAGTGCATCCAGTATGG

14011 TGCGGTCAGCACCCACTGGG 14012 TGCGCTGCGGTCAGCACCCA

14013 CGCAGTGCGCTGCGGTCAGC

14014 TCCCACGCAGTGCGCTGCGG

14015 TCCGGTCCCACGCAGTGCGC

14016 TGACGTCCGGTCCCACGCAG 14017 GGGCGGCCAGATCCTTGACG

14018 CCTGAGGGCGGCCAGATCCT

14019 TGCACCCTGAGGGCGGCCAG

14020 GCAGTTGCACCCTGAGGGCG

14021 ACCGGCAGCAGCTGGTCCTG 14022 TGCTGACCGGCAGCAGCTGG

14023 GATCCTGCTGACCGGCAGCA

14024 ACGATGATCCTGCTGACCGG

14025 CGGTGTAGAACTGTGGGTGC

14026 CTGGACGGTGTAGAACTGTG 14027 CCGATCTGGACGGTGTAGAA

14028 CCGCTCCGATCTGGACGGTG

14029 GATGTCCGCTCCGATCTGGA

14030 AGGGCGATGTCCGCTCCGAT

14031 CCAGCAGGGCGATGTCCGCT 14032 CAGCTCCAGCAGGGCGATGT

14033 CCGGCTCCTCCAGCTCCAGC

14034 CTTCACCGGCTCCTCCAGCT

14035 GAGACCTTCACCGGCTCCTC

14036 GGCTGGAGACCTTCACCGGC 14037 GACGTGGCTGGAGACCTTCA

14038 GTGTGGACGTGGCTGGAGAC

14039 TGACCGTGTGGACGTGGCTG

14040 CAGGGTGACCGTGTGGACGT

14041 GGGGGCAGGGTGACCGTGTG 14042 AGGCAGGGGGCAGGGTGACC

14043 CTCTGAGGCAGGGGGCAGGG

14044 AAGGTCTCTGAGGCAGGGGG

14045 GGGGGAAGGTCTCTGAGGCA

14046 CCCCGGGGGGAAGGTCTCTG 14047 AGGCGCTCATCATTGTCCAC

14048 GTGGGAGGCGCTCATCATTG

14049 TGGCGGTGGGAGGCGCTCAT

14050 GGAAATGGCGGTGGGAGGCG

14051 TCAGAGGAAATGGCGGTGGG 14052 CTGCTTCAGAGGAAATGGCG

712 14053 TTCACCTGCTTCAGAGGAAA

14054 GGACCTTCACCTGCTTCAGA

14055 GGACGATGCGGACGTCGTCT

14056 GTCACGGACGATGCGGACGT 14057 ATGTCGTCACGGACGATGCG

14058 ACAGCATGTCGTCACGGACG

14059 GGCTGTTCCCGGCACACAGC

14060 CCTCTGGCTGTTCCCGGCAC

14061 GAGTCCCTCTGGCTGTTCCC 14062 TGCAGGAGTCCCTCTGGCTG

14063 GCCCTTGCAGGAGTCCCTCT

14064 GAGTCGCCCTTGCAGGAGTC

14065 CTCCAGAGTCGCCCTTGCAG

14066 GGGCCCTCCAGAGTCGCCCT 14067 ACCAGGGGCCCTCCAGAGTC

14068 TGCACACCAGGGGCCCTCCA

14069 TAGCCAGGTGCCATTCACCT

14070 GCCTGTAGCCAGGTGCCATT

14071 CGCCCGCCTGTAGCCAGGTG 14072 GACCACGCCCGCCTGTAGCC

14073 CGTCCCAGCTGACCACGCCC

14074 GCCCTCGTCCCAGCTGACCA

14075 GCACAGCCCTCGTCCCAGCT

14076 GCTGGGCACAGCCCTCGTCC PDE4A

14077 TCAGGTAGGGTCTCCACCTG

14078 TCTCCACCTGACCCCCCGCC

14079 ACCCCCCGCCACCAGGAGCT

14080 ACCAGGAGCTGGGAGTGCGG 14081 GGGAGTGCGGATGTGTCCTC

14082 ATGTGTCCTCCCCAAATGTC

14083 CCCAAATGTCCCTGCGCAGG

14084 CCTGCGCAGGCACTGCAAGC

14085 CACTGCAAGCCCTCTTGGCA 14086 CCTCTTGGCAGCCTGGTGCT

14087 GCCTGGTGCTCTCGTTGGGC

14088 CTCGTTGGGCCTCCACCTCG

14089 CTCCACCTCGGCCGCCGTGG

14090 GCCGCCGTGGAGGGGAGGCC 14091 AGGGGAGGCCCGGGAGGCCC

14092 CGGGAGGCCCGGGGCATGCT

14093 GGGGCATGCTCTGAAACAGA

14094 CTGAAACAGACAGGGTCCTC

14095 CAGGGTCCTCCAAGCAGGGA 14096 CAAGCAGGGAGAAGGGGGCT

14097 GAAGGGGGCTTTGAAGAGCC

14098 TTGAAGAGCCAGGGCAGAGG

14099 AGGGCAGAGGGGCTGCTGTG

14100 GGCTGCTGTGGCTTACAGCA 14101 GCTTACAGCAACCACGAATT

14102 ACCACGAATTCCTCCCGGGA

14103 CCTCCCGGGACGAGAACTCA

14104 CGAGAACTCATCCGGAGCCA

14105 TCCGGAGCCACAGGTGCACT 14106 CAGGTGCACTGCCTGTGGAC

14107 GCCTGTGGACTGTGCCTGCT

14108 TGTGCCTGCTGTGTCAAATA

14109 GTGTCAAATACACTGCCTCC

14110 CACTGCCTCCAGCTCGGCCT 14111 AGCTCGGCCTCCAGGGATGC

14112 CCAGGGATGCTTCCTGTGCC

14113 TTCCTGTGCCATAACTTCCA

14114 ATAACTTCCAACGACTCCTG

14115 ACGACTCCTGGGCCGGGGAT 14116 GGCCGGGGATGCCTCCCAGG

14117 GCCTCCCAGGCTATGGTTGC

14118 CTATGGTTGCATCCAGAGCT

14119 ATCCAGAGCTTCCTCGACTC

14120 TCCTCGACTCCTGACAATCC 14121 CTGACAATCCCTGCGCAGTC

14122 CTGCGCAGTCAATGCCTCTT

14123 AATGCCTCTTGGGCTGTGCA

14124 GGGCTGTGCACGGTATCTGG

14125 CGGTATCTGGGCCATTGATA 14126 GCCATTGATATTTCTTCCTC

713 14127 TTTCTTCCTCCTCTTCCTCC

14128 CTCTTCCTCCTCCAGCGTCA

14129 TCCAGCGTCAGCTCAAACTG

14130 GCTCAAACTGGAACTTGTCA 14131 GAACTTGTCAGGCAGGGGTG

14132 GGCAGGGGTGGGTGGCCTGG

14133 GGTGGCCTGGCCCCCTTGAC

14134 CCCCCTTGACTCCTCCTCGG

14135 TCCTCCTCGGGTGGCGGAGA 14136 GTGGCGGAGATGGGCTCTGC

14137 TGGGCTCTGCCGGATGGCGC

14138 CGGATGGCGCTGTAGTACCA

14139 TGTAGTACCAGTCCCGGTTG

14140 GTCCCGGTTGTCCTCCAAAG 14141 TCCTCCAAAGTGTCCAAGAT

14142 TGTCCAAGATCTCCTGGGCA

14143 CTCCTGGGCATCTGGGTGGA

_{1 14} TCTGGGTGGACAAGGTCCGC

14145 CAAGGTCCGCCCAGGTCTCC 14146 CCAGGTCTCCCACAATGGGT

14147 CACAATGGGTGCACAATGTA

14148 GCACAATGTAGTCAATAAAA

14149 GTCAATAAAACCCACCTGAG

14150 CCCACCTGAGACTTCTCCAC 14151 ACTTCTCCACGGAGGCAGTG

14152 GGAGGCAGTGTGCTTGTCAC

14153 TGCTTGTCACACATGGGGCT

14154 ACATGGGGCTGATTTCCATG

14155 GATTTCCATGCCACGCTCGC 14156 CCACGCTCGCGCTCTCGGTC

14157 GCTCTCGGTCACCCTGCTGG

14158 ACCCTGCTGGAAGAACTCGG

14159 AAGAACTCGGCCATGATGCG

14160 CCATGATGCGGTCTGTCCAC 14161 GTCTGTCCACTGGCGGTACA

14162 TGGCGGTACAGCTCCAGCGG

14163 GCTCCAGCGGCTTGGTGGGG

14164 CTTGGTGGGGTTGCTGAGGT

14165 TTGCTGAGGTCGGCACAGTG 14166 CGGCACAGTGCACCATGTTC

14167 CACCATGTTCCGGAGGACCT

14168 CGGAGGACCTGGATGCGGTC

14169 GGATGCGGTCGGAGTAGTTA

14170 GGAGTAGTTATCTAGCAGGA 14171 TCTAGCAGGAGGACCCCTGA

14172 GGACCCCTGAGCTGGTCACT

14173 GCTGGTCACTTTCTTGGTCT

14174 TTCTTGGTCTCCACCATGGT

14175 CCACCATGGTCTTCAGGTCA 14176 CTTCAGGTCAGCCAGGAGGG

14177 GCCAGGAGGGTCATGTGCTT

14178 TCATGTGCTTGGACATGTCC

14179 GGACATGTCCGTGGCCAGCA

14180 GTGGCCAGCACCATGTCGAT 14181 CCATGTCGATGACCATCTTG

14182 GACCATCTTGCGTAGGCTCT

14183 CGTAGGCTCTGCCGCTGGCG

14184 GCCGCTGGCGCTTGCTGAGG

14185 CTTGCTGAGGTTCTGGAAGA 14186 TTCTGGAAGATGTCGCAGTT

14187 TGTCGCAGTTGTCCTCCTGC

14188 GTCCTCCTGCAGCAGCTTGA

14189 AGCAGCTTGAAGCCCACGGC

14190 ' AGCCCACGGCCAGGTGGTGA 14191 CAGGTGGTGATTCTCGAGCA

14192 TTCTCGAGCACCGACTCATC

14193 CCGACTCATCGTTGTACATG

14194 GTTGTACATGAGCGCCAGCT

14195 AGCGCCAGCTCCGAATTGGT 14196 CCGAATTGGTGTTGATGAGG

14197 GTTGATGAGGAACTGGTTGG

14198 AACTGGTTGGAGACCCCAGG

14199 AGACCCCAGGGTGATCCACA

14200 ^' GTGATCCACATCGTGGATGG 14201 TCGTGGATGGCAGCCGCGAA

714 14202 CAGCCGCGAAGAGGGCGGCG

14203 GAGGGCGGCGAGAATCTCCA

14204 AGAATCTCCAGGTCCGTGAA

14205 GGTCCGTGAACACTGCATCT 14206 CACTGCATCTAGTGCAGGCG

14207 AGTGCAGGCGTGGCCAGCAG

14208 TGGCCAGCAGTACGTGGGTG

14209 TACGTGGGTGGACTGCAGCA

14210 GACTGCAGCACGTCAGCTGC 14211 CGTCAGCTGCGTGCAGGCTG

14212 GTGCAGGCTGTTATGGTAGG

14213 TTATGGTAGGCCACGTCAGC

14214 CCACGTCAGCGTGGTAGTGA

14215 GTGGTAGTGATCCTCCAGCG 14216 TCCTCCAGCGTCAGCATGTA

14217 TCAGCATGTATGTCACCATC

14218 TGTCACCATCGTGTCCACCG

14219 GTGTCCACCGGGATGCGGAA

14220 GGATGCGGAATTTCTTCAGC 14221 TTTCTTCAGCAGGTCCCGCT

14222 AGGTCCCGCTCCTGGAATAT

14223 CCTGGAATATCATGTACATG

14224 CATGTACATGATGCAGGTGA

14225 ATGCAGGTGAGTGAGCGGCC 14226 GTGAGCGGCCTCCAGCGTAA

14227 TCCAGCGTAATCCGACACGC

14228 TCCGACACGCAAAAGATGTT

14229 AAAAGATGTTCAGGCCCCAC

14230 CAGGCCCCACTTGTTCAGGT 14231 TTGTTCAGGTTCTCCAGTTC

14232 TCTCCAGTTCTTGGGCCAGG

14233 TTGGGCCAGGAGCTCTTCTT

14234 AGCTCTTCTTGATCGGTCTT

14235 GATCGGTCTTCACCCCAAAT 14236 CACCCCAAATCGGGGAATGT

14237 CGGGGAATGTTAGAGTTGTT

14238 TAGAGTTGTTCAGGCTGTTA

14239 CAGGCTGTTACTATGCATCA

14240 CTATGCATCAACTTTTTCAA 14241 ACTTTTTCAACCCTGTGATT

14242 CCCTGTGATTTGGGACATGG

14243 TGGGACATGGGCTGTAAGTG

14244 GCTGTAAGTGTGGTACAGGG

14245 TGGTACAGGGGGCGGGGGCG 14246 GGCGGGGGCGGCTGGGAGGG

14247 GCTGGGAGGGTCTTGGTCGC

14248 TCTTGGTCGCGGCGCTTGCT

14249 GGCGCTTGCTGTTTTTCTCG

14250 GTTTTTCTCGTTCCTTCATC 14251 TTCCTTCATCGTGGGTGATG

14252 GTGGGTGATGGGATCTCCAC

14253 GGATCTCCACTTCATTCTGT

14254 TTCATTCTGTTTGTCCAGGA

14255 TTGTCCAGGAATGTTGTGGA 14256 ATGTTGTGGAAATGTACTCT

14257 AATGTACTCTGAGACCTGGT

14258 GAGACCTGGTTTCCGGACCT

14259 TTCCGGACCTGCTCATTTCT

14260 GCTCATTTCTGACAGGTGTG 14261 GACAGGTGTGTGAGCTCACG

14262 TGAGCTCACGGTTCAACATC

14263 GTTCAACATCCTTTTGAACT

14264 CTTTTGAACTGGTCCCACCA

14265 GGTCCCACCAGCCCACCAGC 14266 GCCCACCAGCCAAGGCTTAG

14267 CAAGGCTTAGAGCAGGTCTC

14268 AGCAGGTCTCGCAGAAGAAA

14269 GCAGAAGAAATCCACCAAGG

14270 TCCACCAAGGGCATCTTGGA 14271 GCATCTTGGAGACTTAGCCC

PDE4A-MTA

14272 CCATGATGCGGTCTGTCCA

14273 TCTTCAGCAGGTCCCGCTCCTG

14274 AACTGGTTGGAGACCCCAGG 14275 CCTGCAGCAGCTTGAAGCCCAC

715 14276 GCTGAGGTTCTGGAAGAT

14277 GTGGCCAGCACCATGTC

14278 TTCTTGGTCTCCACCATGGTCTT

14279 CAGCGGCTTGGTGGGGTTGCT 14280 GTCCACTGGCGGTACAG

14281 TGCTTGTCACACATGGG

14282 GTCCACTGGCGGTACAGCT

14283 TGTGCTTGTCACACATGGGGCT

14284 TTGTCCTCCAAAGTGTCCAA 14285 CTTGGTGGGGTTGCTCAG

14286 AGAGTCAGTTCAAACTG

14287 AAGACCCCATTTGTTCA

14288 TCTGCCCATGTCTCCCA

14289 AACTTGTTGGAGGCCATCTC 14290 CGGTCCGTCCACTGGCGGTACAG

14291 TGCTTGTCACACATGGG PDE4C

14292 _{TTTTTTTTTTTTT}^_TTTTTG 14294 TTTTTTGAGACAGTGTCTTG

14295 CAGTGTCTTGCTCTGTCAGC

14296 CTCTGTCAGCCCCAGGCTGG

14297 CCCAGGCTGGAGTGCAGTGG

14298 AGTGCAGTGGCATGATGTCG 14299 CATGATGTCGGCTCACTGCA

14300 GCTCACTGCAACCTCCACCT

14301 ACCTCCACCTCCTGAATTCA

14302 CCTGAATTCAAGTGATTCTC

14303 AGTGATTCTCCTGCCTCAGC 14304 CTGCCTCAGCCTCCCCAGTA

14305 CTCCCCAGTAGCTGGGATTA

14306 GCTGGGATTACAGGCACCCG

14307 CAGGCACCCGCCACCATGCC

14308 CCACCATGCCCAGCCAATTT 14309 CAGCCAATTTTTGTATTTTT

14310 TTGTATTTTTAGTAGAGATG

14311 AGTAGAGATGGGGTTTCACC

14312 GGGTTTCACCATGTTGGCCA

14313 ATGTTGGCCAGGCTGGTCTC 14314 GGCTGGTCTCGAACTCCTAA

14315 GAACTCCTAACCTCAGGTGA

14316 CCTCAGGTGATCCACCTGCC

14317 TCCACCTGCCTCAGCCTCCC

14318 TCAGCCTCCCAAAGTGCTGG 14319 AAAGTGCTGGGATTATAGGC

14320 GATTATAGGCATGGGCCACT

14321 ATGGGCCACTGTGCTCGGCC

14322 GTGCTCGGCCTCAGAGCCCC

14323 TCAGAGCCCCGTCTCTTTCC 14324 GTCTCTTTCCTTTCCTTCTC

14325 TTTCCTTCTCTTTTCTTTTT

14326 TTTTCTTTTTATTTTTAGAC

14327 ATTTTTAGACAGGATCTTGC

14328 AGGATCTTGCTGTGTTGCCC 14329 TGTGTTGCCCAGGCTGGAGT

14330 AGGCTGGAGTGCAGTGATGC

14331 GCAGTGATGCAGTCATAGCT

14332 AGTCATAGCTCTCTTCAGCC

14333 CTCTTCAGCCTCCAACTCCT 14334 TCCAACTCCTGGGCTCAAGC

14335 GGGCTCAAGCGATCCCCTTT

14336 GATCCCCTTTGTCTCAACCT

14337 GTCTCAACCTTCTGAGTAGC

14338 TCTGAGTAGCTGGGATTCTC 14339 TGGGATTCTCAGGTGCACAC

14340 AGGTGCACACCACCATGCCT

14341 CACCATGCCTGGCTAATTTT

14342 GGCTAATTTTTTTTTTCAGA

14343 TTTTTTCAGAGATGGTGGGG 14344 GATGGTGGGGGTCTTGCTAT

14345 GTCTTGCTATGTTGCCCAGG

14346 GTTGCCCAGGCTGGTCTCAA

14347 CTGGTCTCAAACTCCTGAGC

14348 ACTCCTGAGCTTAAGCAGTC 14349 TTAAGCAGTCCTCCCACCTC

716 14350 CTCCCACCTCAGCCTCCCAA

14351 AGCCTCCCAAAGTACCGGGA

14352 AGTACCGGGATTACAGGCAT

14353 TTACAGGCATAAGCCACTAT 14354 AAGCCACTATGCCTTGCCCA

14355 GCCTTGCCCAGCCCTTCTTT

14356 GCCCTTCTTTTCTGCTCCTC

14357 TCTGCTCCTCTTCCTGCCCC

14358 TTCCTGCCCCCTACCGTAGT 14359 CTACCGTAGTTTCAGAAACA

14360 TTCAGAAACAAAACTGGGTA

14361 AAACTGGGTATGAGTGAAGC

14362 TGAGTGAAGCTTTGGTGCTG

14363 TTTGGTGCTGAAAATTTTCC 14364 AAAATTTTCCCCACTCACAT

14365 CCACTCACATTTCCATGCTC

14366 TTCCATGCTCTTGCAGAGAG

14367 TTGCAGAGAGCCGCTTGGTA

14368 CCGCTTGGTAGAGGAAGACA 14369 GAGGAAGACAGGGAGATGCC

14370 GGGAGATGCCTTTGGGATGG

14371 TTTGGGATGGTCTCCTGACT

14372 TCTCCTGACTCCCCACCCTT

14373 CCCCACCCTTTGTGCAGGGC 14374 TGTGCAGGGCTACTACAGAG

14375 TACTACAGAGGCAGAAAGCT

14376 GCAGAAAGCTGGCCCGAAGT

14377 GGCCCGAAGTAGATGAGCAA

14378 AGATGAGCAATAAATATTTG 14379 TAAATATTTGATAAAGAAGG

14380 ATAAAGAAGGAAATAATTAA

14381 AAATAATTAAGTGACAGATG

14382 GTGACAGATGTGACTCAAGA

14383 TGACTCAAGAGTGACCACTG 14384 GTGACCACTGGAGAGGGTGG

14385 GAGAGGGTGGACTAGAGGCT

14386 ACTAGAGGCTCCAGCAGACA

14387 CCAGCAGACAGCACCTCTCC

14388 GCACCTCTCCTCACAGGGAT 14389 TCACAGGGATAGAAGCCCAG

14390 AGAAGCCCAGGAGAAAGACA

14391 GAGAAAGACACCAGGGCATC

14392 CCAGGGCATCGTAAGAGGCT

14393 GTAAGAGGCTGCCCCTTAGA 14394 GCCCCTTAGAGAGCTCTTTT

14395 GAGCTCTTTTAGGCAAGTCT

14396 AGGCAAGTCTAGGGTCAGAG

14397 AGGGTCAGAGTGGACCCCAG

14398 TGGACCCCAGCCAGGTGCCT 14399 CCAGGTGCCTCCAATTAGAC

14400 CCAATTAGACCCTGGGAGCC

14401 CCTGGGAGCCACCTATAACT

14402 ACCTATAACTAAGAGCTTGA

14403 AAGAGCTTGATTGTCTCCCT 14404 TTGTCTCCCTAAATGGGTGG

14405 AAATGGGTGGGAAAGTGAAG

14406 GAAAGTGAAGCAGGAGCCAC

14407 CAGGAGCCACATGGAGCCTC

14408 ATGGAGCCTCTTCCTGGAAA 14409 TTCCTGGAAAGTCTGCCTGC

14410 GTCTGCCTGCCAAGAGCCAA

14411 CAAGAGCCAAAGGGCTTTAC

14412 AGGGCTTTACCATCCATTGC

14413 CATCCATTGCCCCTGCAGTT 14414 CCCTGCAGTTCACGCAGGGC

14415 CACGCAGGGCTGGCCCTAAG

14416 TGGCCCTAAGTCCTCTGGTT

14417 TCCTCTGGTTGTCGAGGGGT

14418 GTCGAGGGGTAAGTCCCCAG 14419 AAGTCCCCAGGGTCTGGGCC

14420 GGTCTGGGCCGGCTTCAGGG

14421 GGCTTCAGGGGACAGGAGTT

14422 GACAGGAGTTCAGTGTCAGG

14423 CAGTGTCAGGCAACTCCAAG 14424 CAACTCCAAGGCCTCTTTGG

717 14425 GCCTCTTTGGCTAAAGCTGT

14426 CTAAAGCTGTCTCTTCCCCC

14427 CTCTTCCCCCTCCTCTTCTT

14428 TCCTCTTCTTCCTCCTCATC 14429 CCTCCTCATCCTCTTCCTCT

14430 CTCTTCCTCTGCCTCCTCCA

14431 GCCTCCTCCAGAGTCAGTTC

14432 GAGTCAGTTCAAACTGGAAT

14433 AAACTGGAATCTGTCAGGCC 14434 CTGTCAGGCCCGTCCCGCTC

14435 CGTCCCGCTCGGGGTTGGTG

14436 GGGGTTGGTGAGGTCTGAGG

14437 AGGTCTGAGGGACTTCGGGG

14438 GACTTCGGGGGATCTTGCTC 14439 GATCTTGCTCTGGTACCACT

14440 TGGTACCACTCTCGATTGTC

14441 CTCGATTGTCCTCCAGCGTG

14442 CTCCAGCGTGTCCAGCAGGT

14443 TCCAGCAGGTCCTGTGCATC 14444 CCTGTGCATCTGGGTGGACC

1_{4 4}5 TGGGTGGACCAGGTCAGCCC

14446 AGGTCAGCCCAAGTCTCCCA

14447 AAGTCTCCCACAGTGGGTGA

14448 CAGTGGGTGAGCAATGTAGT 14449 GCAATGTAGTCAATGAAACC

14450 CAATGAAACCCACCTGGGAC

14451 CACCTGGGACTTCTCCACTG

14452 TTCTCCACTGAGGCCGTATG

14453 AGGCCGTATGCTTGTCACAC 14454 CTTGTCACACATGGGACTGA

14455 ATGGGACTGATGTCCAGGCC

14456 TGTCCAGGCCCGACTCACGC

14457 CGACTCACGCTCGCGGTCTC

14458 TCGCGGTCTCCCTGCTGGAA 14459 CCTGCTGGAAGAACTCGGCC

14460 GAACTCGGCCATGATGCGGT

14461 ATGATGCGGTCCGTCCACTG

14462 CCGTCCACTGGCGGTACAGG

14463 GCGGTACAGGGGCAGCGGCT 14464 GGCAGCGGCTTGGTGGGGTT

14465 TGGTGGGGTTGCTCAGATCA

14466 GCTCAGATCAGCACAGTGCA

14467 GCACAGTGCACCAGGTTCTG

14468 CCAGGTTCTGCAAGACCTGG 14469 CAAGACCTGGATTCGGTCGG

14470 ATTCGGTCGGAATAGTTGTC

14471 AATAGTTGTCCAGGAGGAGG

14472 CAGGAGGAGGACACCGAGGC

14473 ACACCGAGGCTTGTCACCTT 14474 TTGTCACCTTCTTGGTCTCC

14475 CTTGGTCTCCACCATGGTCT

14476 ACCATGGTCTTGAGGTCGGC

14477 TGAGGTCGGCCAGGAGGTTC

14478 CAGGAGGTTCATGTGTTTGG 14479 ATGTGTTTGGACATGTCTGT

14480 ACATGTCTGTGGCCAGCACC

14481 GGCCAGCACCATGTCAATGA

14482 ATGTCAATGACCATCCTGCG

14483 CCATCCTGCGCAGACTCAGT 14484 CAGACTCAGTCGCTGCTTGG

14485 CGCTGCTTGGCGCTGAGGTT

14486 CGCTGAGGTTCTGGAAGATA

14487 CTGGAAGATATCGCAGTTCT

14488 TCGCAGTTCTCTGCCTGCAG 14489 CTGCCTGCAGCAGCTTGAAG

14490 CAGCTTGAAGCCCACAGCCA

14491 CCCACAGCCAGGTGATGGTT

14492 GGTGATGGTTCTCCAGCACC

14493 CTCCAGCACCGAGGCGTCGT 14494 GAGGCGTCGTTGTACATAAG

14495 TGTACATAAGCGCCACGTCT

14496 CGCCACGTCTGAGTTGGTGT

14497 GAGTTGGTGTTAATCAGAAA

14498 TAATCAGAAACTGGTTGGAG 14499 CTGGTTGGAGACCCCAGGAT

718 14500 ACCCCAGGATGGTCCACGTC

14501 GGTCCACGTCGTGGATGGCG

14502 GTGGATGGCGCTTGCAAAGA

14503 CTTGCAAAGAGGGCAGCCAG 14504 GGGCAGCCAGGATTTCCAAG

14505 GATTTCCAAGTCTGTGAACA

14506 TCTGTGAACACAGCCTCGAG

14507 CAGCCTCGAGGGCGGGCGTA

14508 GGCGGGCGTAGCCAGCAGCA 14509 GCCAGCAGCACATGCGTGGA

14510 CATGCGTGGACTGGGCCACG

14511 CTGGGCCACGTCGGCGGCAT

14512 TCGGCGGCATGTAGGCTGTT

14513 GTAGGCTGTTGTGGTAGGCC 14514 GTGGTAGGCCACATTGGCGT

14515 ACATTGGCGTGGTAGTGACC

14516 GGTAGTGACCCTCCAGCATC

14517 CTCCAGCATCAGCAGGTAGG

14518 AGCAGGTAGGTGGCCAGTGT 14519 TGGCCAGTGTGTCTGCTGGG

14520 GTCTGCTGGGATCTGGAATG

14521 ATCTGGAATGTCTTCAGCAG

14522 TCTTCAGCAGGTCCCGCTCC

14523 GTCCCGCTCCTGAAAAATGC 14524 TGAAAAATGCTGAATATGAT

14525 TGAATATGATAGCTGTGAGG

14526 AGCTGTGAGGGGCCGGTTCC

14527 GGCCGGTTCCCACTTACGTC

14528 CACTTACGTCCGCCACCTTG 14529 CGCCACCTTGAACACATCAA

14530 AACACATCAAGTCCCCACTT

14531 GTCCCCACTTGTTGGTGTCT

14532 GTTGGTGTCTTCTAGCTCCT

14533 TCTAGCTCCTTGGCCAGTTG 14534 TGGCCAGTTGCTCCTCCTGG

14535 CTCCTCCTGGTCAGTCTGGA

14536 TCAGTCTGGACCCCAAAGCG

14537 CCCCAAAGCGTGGGACAGTG

14538 TGGGACAGTGGCTGAGGAGA 14539 GCTGAGGAGAGGCTGGCACT

14540 GGCTGGCACTGTGGCAGAGC

14541 GTGGCAGAGCCCATGTAGGC

14542 CCATGTAGGCCACTGATCCG

14543 CACTGATCCGGGACATGGGC 14544 GGACATGGGCTGTGGGGCCT

14545 TGTGGGGCCTCCTCAGCGGT

14546 CCTCAGCGGTCACCTTGGGC

14547 CACCTTGGGCAGCTCCACCT

14548 AGCTCCACCTCGGTCTGCTG 14549 CGGTCTGCTGGTCCAGGAAG

14550 GTCCAGGAAGGTCCGGGAGA

14551 GTCCGGGAGATGTACTCGGA

14552 TGTACTCGGACACCTGGTTC

14553 CACCTGGTTCCCGGAGCGGC 14554 CCGGAGCGGCTGGTTTCGGA

14555 TGGTTTCGGACAGGTGGGTC

14556 CAGGTGGGTCAACTCCCGGT

14557 AACTCCCGGTTCAGGATCCG

14558 TCAGGATCCGCTTGAACTTG 14559 CTTGAACTTGTTGGAGGCCA

14560 TTGGAGGCCATCTCCCCCAC

14561 TCTCCCCCACCGAGTGCCGG

14562 CGAGTGCCGGGTCTGCAGCG

14563 GTCTGCAGCGTCTCCAACTG 14564 TCTCCAACTGATCCAGGCAC

14565 ATCCAGGCACCAGTCCAGCT

14566 CAGTCCAGCTCGTCTAGCGT

14567 CGTCTAGCGTCTCCAATGCC

14568 CTCCAATGCCAGCTTCTGCC 14569 AGCTTCTGCCCCGTGTCCTC

14570 CCGTGTCCTCTGCAGGAGGG

14571 TGCAGGAGGGAGCTGATTGC

14572 AGCTGATTGCTGGATGAAGG

14573 TGGATGAAGGGTTTCCGACG 14574 GTTTCCGACGGGTCCCTGCT

719 14575 GGTCCCTGCTTGGCTGCTCC

14576 TGGCTGCTCCTAGGCATTGC

14577 TAGGCATTGCTGGCGGGCAA

14578 TGGCGGGCAAGGGCCGCCAC 14579 GGGCCGCCACGTTGCTCCGA

14580 GTTGCTCCGAACGGTCCGCA

14581 ACGGTCCGCAGACTGGCCAG

14582 GACTGGCCAGGACCTGGGCA

14583 GACCTGGGCAAAGGGCGTCA 14584 AAGGGCGTCACAATCATGTC

14585 CAATCATGTCCTCTCCATGT

14586 CTCTCCATGTAGGTCGCTGG

14587 AGGTCGCTGGCCACAGAGGA

14588 CCACAGAGGAGTTCCGAGAC 14589 GTTCCGAGACATGGCCTTGG

14590 ATGGCCTTGGGCGAGAGTTC

14591 GCGAGAGTTCATAGTCGCTA

14592 ATAGTCGCTATCTGAGCGGT

14593 TCTGAGCGGTACAGGAAGGA 14594 ACAGGAAGGACTCGCGCCGC

14595 CTCGCGCCGCTGGCTGTGCG

14596 TGGCTGTGCGGGACTGGAGC

14597 GGACTGGAGCCTGCATAATC

14598 CTGCATAATCCGGCCCAGGC 14599 CGGCCCAGGCCAGGGCTGGA

14600 CAGGGCTGGACTGAGGGTCC

14601 CTGAGGGTCCAGGGCCCTCC

14602 AGGGCCCTCCTCCCACACGA

14603 TCCCACACGAGAGCCCATTT 14604 GAGCCCATTTTCCAGGTCAA

14605 TCCAGGTCAAAGCGCCTGCA

14₆06 AGCGCCTGCAGGAGGAAACG

14607 GGAGGAAACGGGCCAGGAGA

14608 GGCCAGGAGAGCCGCGACTT 14609 GCCGCGACTTCCTGAGCTCC

14610 CCTGAGCTCCGGCCGCGGGC

14611 GGCCGCGGGCTCAGGTCCCT

14612 TCAGGTCCCTCTCGCGGCAG

14613 CTCGCGGCAGCCCGCGGACT 14614 CCCGCGGACTTGTCCGGATC

14615 TGTCCGGATCCGAATAGAAG

14616 CGAATAGAAGCGCTGTTGGA

14617 CGCTGTTGGATGCGGATGGG

14618 TGCGGATGGGGCGCCGGGGT 14619 GCGCCGGGGTTGCCGCCACA

14620 TGCCGCCACAGGTGCTTCGG

14621 GGTGCTTCGGGGCTCTGGTC

14622 GGCTCTGGTCATGCTGTGGC

14623 ATGCTGTGGCGGCCGCGAGA 14624 GGCCGCGAGAGCGACTCAAC

14625 GCGACTCAACCTGCTGCAAG

14626 CTGCTGCAAGCCTCTGCCCC

14627 CCTCTGCCCCTTCGCCGACC

14628 TTCGCCGACCCCCAGGTTCT 14629 CCCAGGTTCTCCATGCGCCA

14630 CCATGCGCCAGAGAAAGGCT

14631 GAGAAAGGCTGGATGAAGGG

14632 GGATGAAGGGTTTCCGACGG

14633 TTTCCGACGGGTCCCTGCTT 14634 GTCCCTGCTTGGCTGCTCCT

14635 GGCTGCTCCTAGGCATTGCT

14636 AGGCATTGCTGGCGGGCAAG

14637 GGCGGGCAAGGGCCGCCACG

14638 GGCCGCCACGTTGCTCCGAA 14639 TTGCTCCGAACGGTCCGCAG

In one preferred embodiment, the links between neighboring mononucleotides are phosphodiester links. In another preferred, at least one mononucleotide phosphodiester residue of the anti-sense oligonucleotide(s) is substituted by a methylphosphonate, phosphotriester, phosphorothioate, phosphorodithioate, boranophosphate, formacetal, thioformacetal, thioether, carbonate, carbamate, sulfate, sulfonate, sulfamate, sulfonamide, sulfone, sulfite, sulfoxide, sulfide, hydroxylamine, 2'-0-methyl, memylene(methyimino), methyleneoxy (methylimino), phosphoramidate residues, and combinations thereof. The oligos having one or more phosphodiester residues substituted by one or more of the other residues are generally longer lasting, given that these residues are more

720 resistant to hydrolysis than the phosphodiester residue. In some cases up to about 10%, about 30%, about 50%, about 75%, and even all phosphodiester residues may be substituted (100%).

In another preferred embodiment, the multiple target anti-sense oligo (MTA) of the invention comprises at least about 7 mononucleotides, in some instances up to 60 and more mononucleotides, preferably about 10 to about 36, and more preferably about 12 to about 21 mononucleotides. However, other lengths are also suitable depending on the length of the target macromolecule. Examples of multi-targeted anti-sense (MTA) oligos of the invention are provided in Table 3 below, which includes ninety-four sequences (SEQ ID NOS.: 2316 through 2410). Table 3: MTA Oligos, Location Targeted & Target

MTA Oligo SEQ ID Location Compound Target

No. Targeted

HUMNFKBP65A AS

CCC GGC CCC GCC TCG TGC C 12388 5'=1 EPI 2192

CGT CCB TGC CGC GGG CCC 12389 5'=28(AUG)EPI 2193

GCC CCG CTG CTT GGG CTG CTC TGC CGG G 12390 5'=65 EPI 2194

TCT GTG CTC CTC TCG CCT GGG 12391 5'=137 EPI 2195

TGG TGG GGT GGG TCT TGG TGG 12392 5'=159 EPI 2196

CTG TCC CTG GTC CTG TG 12393 5' = 196 EPI 2197

GGT CCC GCT TCT TC 12394 5' = 362 EPI 2198

GGG GTT GTT GTT GGT CTG G 12395 5'=401 EPI 2199

TGT CCT CTT TCT GC 12396 5'=656 EPI 2200

GCC TCG GGC CTC CC 12397 5'=697 EPI 2201

GGC TGG GGT CTG CGT 12398 5' = 769 EPI 2202

GGC CGG GGG TCG GTG GGT CCG CTG 12399 5'=953 EPI 2203

GGG CTG GGG TGC TGG CTT GGG G 12400 5'=1022 EPI 2204

GGG GCT GGG GCC TGG GCC 12401 5'=1208 EPI 2205

GCC TGG GTG GGC TTG GGG GC 12402 5'=1272 EPI 2206

GCT GGG TCT GTG CTG TTG CC 12403 5'=1362 EPI 2207

GTT GTG TGG GGG GCC 12404 5'= 1451 EPI 2208

GCT GGG TCG GGG GGC CTC TGG GCT GTC 12405 5'=1511 EPI 2209

GCC CCG GGG CCC CC 12406 5'=1550 EPI 2210

TGG CTC CCC CCT CC 12407 5' = 1772 EPI 2211

GCT CCC CCC TTT CC 12408 5'=1863 EPI 2212

CGG ACG AAG ACA GAG A 12409 5'=1979 EPI 2213

GGC TTT GTG GGC TC 12410 5'=2011 EPI 2214

GCC TGC TCT CCC CC 12411 5' = 2312 EPI 2215

CCC GGC CCC GCC BCG BBC C 12412 intron EPI 2192-01A HSU501₃6C4Synth

CCC GGC CCC GCC BCG 12413 intron EPI 2192-01B

CCC GGC CCC GCC BCG BBC C 12414 5'untr EPI 2192-02A HUMIiIPOX5LO

CCC GGC CCC GCC BCG 12415 5 ' untr EPI 2192-02B

CCC GBC CCC GCC TCB BG 12416 trans EPI 2192-03A HSNFKBS Subunit

CCC GBC CCC GCC TC 12417 trans EPI 2192-03B

CCG GCC CCG CCT C 12418 5'untr EPI 2192-04 TGF|8R1

CCC GBB CCC GCB TBG TGC C 12419 5'trans EPI 2192-05A HSU58198I1 enhan

CCC GCB TBG TGC C 12420 5'untr EPI 2192-05B

CCC GGB CCC BCC BBG TGC C 12421 3'trans EPI 2192-06 HSVECAD

CBG BBC CCG CCT CGT GCC 12422 intron EPI 2192-07A NF B2

C CCG CCT CGT GCC 12423 intron EPI 2192-07B NFKB2

CCG GCB CCG CCT CBT GCC 12424 5'trans EPI 2192-08 Carboxypep

CCG GCC CCG CCB CBT GCC 12425 3'trans EPI 2192-09 HumADRA₂Cα AdrKid

CCC GBC CCC GBC TCG 12426 5 'untr s EPI 2192-10 HU FK506B

CCC GGC CBC GBC TCG 12427 5 'untr s EPI 2192-11 HSNBARKSlβAdrKin

CCC GGC CCB GCC TBG 12428 5'UTR EPI 2192-12 HSNFXNl(NFKBl)

CCC GGC BCB GBC TCG TBC C 12429 3'UTR EPI 2192-13 HSILF (transcrp. Factor ILF)

CCC GGC CCC GCC BCG 12413 EPI- -2192-14 NFKB/C4Syn/5- O/ TGFBrecl MTA

CCC GGC CCC GCC BCG 12430 EPI- -2192-15 NFKB/C4Syn/5- OMTA TCC BTG CCG CGG GC 12432 3' trans EPI-2193-01 METOncogene TCC BTG CCB CGG GCC 12433 3' trans EPI-2193-02 HSFGR2 (IG) TCC BTG CCB CGG GCC 12434 mid cod. EPI- -2193-03 5- O TCC BTG CCB CBG GCC 12435 mid cod EPI- -2193-04 HUMTK1 GTC CBT GBC GCG G 12436 3'trans EPI- -2193-05 HUMTNFR TC CBT GBC GCG GG 12437 AUG Probl . HUMPTCH cardxacK+channel

TCT GBG CTC CTC TBB CCT GGG 12438 intr EPI- -2195-01 humCSPAcytotox . Ser. Protease

CTG TGC BCC TBB CBC CTG GG 12439 intr EPI-2195-02 HSINOSXO 8 indue . NOS TGT GBT CCB CTB GBC TGG G 12440 EPI- -2195-03 HUMACHRM musc . m

721 acetylch.rec.

TCT GTB CTC BBC TCB CCT G 12441 EPI-2195-04 s86371sl Neurokinin3Recept

TGC TCC TCB CBB CTG GG 12442 EPI-2195-05 HUMMIP1 Amacro Inflam. Factor

CTC CTC TBG CCT GG 12443 EPI-2195-06 HSNBARKS4

0-Adr Rec Kinase

GTG CTC CBB TCB BCT GGG 12444 EPI-2195-07 HSTNFR2S06TNF R₂

GTG CBC CBB TCB CCT GGG 12445 EPI-2195-08 humfkbp fk506 binding prot .

TCT GTG CBC CTC TBG BCT 12446 exon EPI-2195-09 HSNBARKSl/3-Adr. Recept .Kinase

CTG TBB TCC TBB CBC CTG G 12482 intron EPI-2195-10 HUMIL8

TGT GCT BBT CBC BCB TGG G 12448 EPI-2195-11 HSUΞ01S7 PDE

GTG CBC CBC TCB CCT G 12449 intron/exon EPI-2195-12 IL-2 R

CTG TGC BCC TCT c 12450 3'UTR EPI-2203-05 IL-6 R HSIL6R

CBG TGC BCC BCT CBC CTG 12451 intr/ex EPI-2203-06A HSI 2rG6

G TGC BCC BCT CBC CTG 12449 intr/ ex EPI-2203-06B HSIL2rG6

CBC CTC TCB CCT GGG 12453 coding EPI-2203-07A HUMI 71

C CTC TCB CCT GGG 12454 coding EPI-2203-07B IL-7 HUMIL71

GCT CCB CTC GCC T 12455 coding EPI-2203-08 IL-6 R HSISRKC

TGC TCC TCB CGC C 12456 intron PDGF A EPI-2303-09 Chain HUMPDGFAB

GTT GTT GBT CTG G 12457 3'utr EPI-2199-01 GATA-4Transcrip.

Factor for IL-5

GGT TGB BBT TGG TCT TGG 12458 Coding EPI-2199-02 TNFα HUMTNFA

GGT TGT TGB TGB TCT G 12459 Far 5'UTR EPI-2199-03 HSSUBPlG(Sub Pr)

GGG TTB BBG TTG BTC TGG 12460 Coding EPI-2199-04 NeutrophilAdh . R HUMNARIA

GGG TTB BBG TTG BTC TGG 12461 HSHM2 EPI-2199-05 ra2 Muscarinic R

TTG TTG TBG BTC TGG 12462 HUMLICA EPI-2199-06 LI LeukAadhProt

GGG TBG BBG BGT CCG CTG 12463 coding EPI-2203-01 HUMGATA2A

GGG TCB GBG GBT CBG CTG 12464 S71424S2 EPI-2203-02 IGE eps

GGG TBG GTG GGT C 12465 coding EPI-2203-03 HSGCSFR2

GGG TCG GBG GGT CBG C 12466 HUMITGF EPI-2203-04 TGF/33

GGG TGG GCT T 12485 HUM K65PR0 EPI-2206-01 NFKB/NK &

TCell

Activating Prot

GGG TGG GCT TGG G 12468 HUMPEREEB EPI 2206-02 NFKB/Prostagl. EP3 Rec

CCTGGGTGGGBBTGGG 12469 EPI 2206-03 HSNF2B/GCSF

] SIFKB/GranuLocCSF/

Transcr . FactorNF2B

CCTGGBTGGGCBTGGG 12470 EPI-2206-04 HUMLAP/NFKB

Leuk . Adhes . Prot

GCCTGBGTGBBCTTGGG 12471 EPI2206-05 NFKB/Endothel

N2 S63833

CCCAVGVCCVCCCAGGC 11769 EPI 2206-06 NFKBAS13/B Lymph

SerThrProt . Kinase

AGCCCACCCAGGC 11770 EPI2206-07 NFKBAS13/GCSF1 HSGCSFRlRec

BCCTGGGTGGGCTB 11771 EPI2206-08 NFKBAS1₃/GCSF1/

NK7TCELLACT . Prot

GGTGGGCTTGGG 11772 EPI 2206-09 NF BAS13/

HSTGFB1 TGFB

CCBBGGTGGGCTTGGG 11773 EPI 2206-10 NFKBAS1₃/

HSTGFB1 TGFB1

CTGGGTGGGBBTGGG 11774 EPI 2206-11 NFKBAS1₃/

HSGCSFR1 GCSFR1

CCBGGGTGGGCTTGG 11775 EPI 2206-12 NFKBAS1₃ /HUMCD30A

LympbAct nt igCoding

GGGTGGGCTTGG 11776 EPI-2206-12B NFKBAS1₃ /HUMCD₃0A

CCTGBGTGBGCBTGGG 11777 EPI 2206-13 NFKBAS13 /HUMCAM1V

Vase . Endoth. Cell

Adh.Molec

B : Universal Base

The MTA oligos of Table 3 as well as many others in accordance with this invention are suitable for use with two or more of the targets listed in Table 4 below.

722 Table 4: Targets for the MTA Oligos of Table 3

The mRNA sequence of the targeted protein may be derived from the nucleotide sequence of the gene expressing the protein, whether for existing targets or those to be found in the future. Sequences for many target genes of different systems are presently known. See, GenBank data base, NIH, the entire sequences of wliich are incorporated here by reference. The sequences of those genes, whose sequences are not yet available, may be obtained by isolating the target segments applying technology known in the art. Once the sequence of the gene, its RNA and/or the protein are known, anti-sense oligonucleotides are produced as described above and utilized to validate the target by in vivo administration and testing for a reduction of the production of the targeted protein in accordance with standard techniques, and of specific functions. As already described above, the anti-sense oligonucleotides may be of any suitable length, e. g., from about 7 to about 60 nucleotides in length, depending on the particular target being bound and the mode of delivery thereof. The anti-sense oligonucleotide preferably is directed to an mRNA region containing a junction between intron and exon or to regions vicinal to the junction.

Where the anti-sense oligonucleotide is directed to an intron/exon junction, it may either entirely overlie the junction or may be sufficiently close to the junction to inhibit splicing out of the intervening exon during processing of precursor mRNA to mature mRNA, e. g., with the 3' or 5' teπninus of the anti-sense oligonucleotide being positioned within about, for example, 10, 5, 3, or 2 nucleotide of the intron/exon junction. Also preferred are anti- sense oligonucleotides wliich overlap the initiation codon and, more generally, those that target the coding region of the target mRNA. When practicing the present invention, the anti-sense oligonucleotides administered may be related in origin to the species to which it is administered. When treating humans, human anti-sense may be used if desired. Anti-sense oligos to endogenous sequences from other species, however, are also encompassed.

723 Other agents that may be incorporated into the present composition are one or more of a variety of therapeutic agents which are administered to humans and animals. Some of the categories of agents suitable for incorporation into the present composition and formulations are analgesics, pre-menstrual medications, menopausal agents, anti-aging agents, anti-anxiolytic agents, mood disorder agents, anti-depressants, anti-bipolar mood agents, anti-schizophrenic agents, anti-cancer agents, alkaloids, blood pressure controlling agents, hormones, anti- inflammatory agents, muscle relaxants, steroids, soporific agents, anti-ischemic agents, anti-arrhythmic agents, contraceptives, vitamins, minerals, tranquilizers, neurotransmitter regulating agents, wound healing agents, anti- angiogenic agents, cytokines, growth factors, anti-metastatic agents, antacids, anti-mstaminic agents, anti-bacterial agents, anti-viral agents, anti-gas agents, appetite suppressants, sun screens, emollients, skin temperature lowering products, radioactive phosphorescent and fluorescent contrast diagnostic and imaging agents, libido altering agents, bile acids, laxatives, anti-diarrheic agents, skin renewal agents, hair growth agents, analgesics, pre-menstrual medications, anti-menopausal agents such as hormones and the like, anti-aging agents, anti-anxiolytic agents, nociceptic agents, mood disorder agents, anti-depressants, anti-bipolar mood agents, anti-schizophrenic agents, anti- cancer agents, alkaloids, blood pressure controlling agents, hormones, anti-inflammatory agents, other agents suitable for the treatment and prophylaxis of diseases and conditions associated or accompanied with pain and inflammation, such as arthritis, burns, wounds, chronic bronchitis, chronic obstructive pulmonary disease (COPD), inflammatory bowel disease such as Crohn's disease and ulcerative colitis, autoimmune disease such as lupus erythematosus, muscle relaxants, steroids, soporific agents, anti-ischemic agents, anti-arrhythmic agents, contraceptives, vitamins, minerals, tranquilizers, neurotransmitter regulating agents, wound and burn healing agents, anti-angiogenic agents, cytokines, growth factors, anti-metastatic agents, antacids, anti-liistaminic agents, antibacterial agents, anti-viral agents, anti-gas agents, agents for reperfusion injury, counteracting appetite suppressants, sun screens, emollients, skin temperature lowering products, radioactive phosphorescent and fluorescent contrast diagnostic and imaging agents, libido altering agents, bile acids, laxatives, anti-diarrheic agents, skin renewal agents, hair growth agents, etc. Among the hormones are female and male sex hormones such as premarin, progesterone, androsterones and their analogues, thyroxine and glucocorticoids, among the libido altering agents are Viagra and otlier NO-level modulating agents, among the analgesics are over-the-counter medications such as ibuprofen, oruda, aleve and acetaminophen and controlled substances such as morphine and codeine, among the anti-depressants are tricyclics, MAO inhibitors and epinephrine, γ-amino butyric acid (GABA), dopamine and serotonin level elevating agents, e. g. Prozac, Amytryptilin, Wellbutrin and Zoloft, among the skin renewal agents are Retin-A, hair growth agents such as Rogaine, among the anti-inflammatory agents are non-steroidal anti-inflammatory drugs (NSAIDs) and steroids, among the soporifics are melatonin and sleep inducing agents such as diazepam, cytoprotective, anti- ischemic and head injury agents such as enadoline, and many others. Examples of agents in the different groups are provided in the following list. Examples of analgesics are Acetaminophen, Anilerdine, Aspirin, Buprenorphine, Butabital, Butorpphanol, Choline Salicylate, Codeine, Dezocine, Diclofenac, Diflunisal, Dihydrocodeine,

Elcatoninin, Etodolac, Fenoprofen, Hydrocodone, Hydromorphone, Ibuprofen, Ketoprofen, Ketorolac, Levorphanol, Magnesium Salicylate, Meclofenamate, Mefenamic Acid, Meperidine, Methadone, Methotrimeprazine, Morphine, Nalbuphine, Naproxen, Opium, Oxycodone, Oxymorphone, Pentazocine, Phenobarbital, Propoxyphene, Salsalate, Sodium Salicylate, Tramadol and Narcotic analgesics in addition to those listed above. See, Mosby's Physician's GenRx. Examples of anti-anxiety agents include Alprazolam, Bromazepam, Buspirone, Chlordiazepoxide,

Chlormezanone, Clorazepate, Diazepam, Halazepam, Hydroxyzine, Ketaszolam, Lorazepam, Meprobamate, Oxazepam and Prazepam, among others. Examples of anti-anxiety agents associated with mental depression are Chlordiazepoxide, Amitriptyline, Loxapine Maprotiline and Perphenazine, among others. Examples of anti- inflammatory agents are non-rheumatic Aspirin, Choline Salicylate, Diclofenac, Diflunisal, Etodolac, Fenoprofen, Floctafenine, Flurbiprofen, Ibuprofen, Indomethacin, Ketoprofen, Magnesium Salicylate, Meclofenamate,

Mefenamic Acid, Nabumetone, Naproxen, Oxaprozin, Phenylbutazone, Piroxicam, Salsalate, Sodium Salicylate, Sulindac, Tenoxicam, Tiaprofenic Acid, Tolmetin. Examples of anti-inflammatories for ocular treatment are Diclofenac, Flurbiprofen, Indomethacin, Ketorolac, Rimexolone (generally for post-operative treatment). Examples of anti-inflammatories for non-infectious nasal applications are Beclomethaxone, Budesonide, Dexamethasone, Flunisolide, Triamcinolone, and the like. Examples of soporifics (anti-insomnia/sleep inducing agents) such as those utilized for treatment of insomnia, are Alprazolam, Bromazepam, Diazepam, Diphenhydramine, Doxylamine, Estazolam, Flurazepam, Halazepam, Ketazolam, Lorazepam, Nitrazepam, Prazepam Quazepam, Temazepam,

724 Triazolam, Zolpidem and Sopiclone, among others. Examples of sedatives are Diphenhydramine, Hydroxyzine, Methotrimeprazine, Promethazine, Propofol, Melatonin, Trimeprazine, and the like. Examples of sedatives and agents used for treatment of petit mal and tremors, among other conditions, are Amitriptyline HCl, Chlordiazepoxide, Amobarbital, Secobarbital, Aprobarbital, Butabarbital, Ethchiorvynol, Glutethimide, L- Tryptophan, Mephobarbital, MethoHexital Na, Midazolam HCl, Oxazepam, Pentobarbital Na, Phenobarbital,

Secobarbital Na, Thiamylal Na, and many others. Agents used in the treatment of head trauma (Brain Injury/Ischemia) include Enadoline HCl (e. g. for treatment of severe head injury, orphan status, Warner Lambert). Examples of cytoprotective agents and agents for the treatment of menopause and menopausal symptoms are Ergotamine, Belladonna Alkaloids and Phenobarbitals. Examples of agents for the treatment of menopausal vasomotor symptoms are Clonidine, Conjugated Estrogens and Medroxyprogesterone, Estradiol, Estradiol

Cypionate, Estradiol Valerate, Estrogens, conjugated Estrogens, esterified Estrone, Estropipate and Ethinyl Estradiol. Examples of agents for treatment of symptoms of Pre Menstrual Syndrome (PMS) are Progesterone, Progestin, Gonadotrophic Releasing Hormone, oral contraceptives, Danazol, Luprolide Acetate and Vitamin B6. Examples of agents for the treatment of emotional/psychiatric treatments are Tricyclic Antidepressants including Amitriptyline HCl (Elavil), Amitriptyline HCl, Perphenazine (Triavil) and Doxepin HCl (Sinequan). Examples of tranquilizers, anti-depressants and anti-anxiety agents are Diazepam (Valium), Lorazepam (Ativan), Alprazolam (Xanax), SSRI's (selective Serotonin reuptake inhibitors), Fluoxetine HCl (Prozac), Sertaline HCl (Zoloft), Paroxetine HCl (Paxil), Fluvoxam ne Maleate (Luvox), Venlafaxine HCl (Effexor), Serotonin, Serotonin Agonists (Fenfluramine), and other over the counter (OTC) medications. Examples of anti-migraine agents are Imitrex and the like.

The amount of each active agent may be adjusted when, and if, additional agents with overlapping activities are included as discussed in this patent. The dosage of the active compounds, however, may vary depending on age, weight, and condition of the subject. Treatment may be initiated with a small dosage, e. g. less than the optimal dose, of the first active agent of the invention, be it a non-glucocorticoid steroid or a ubiquinone, and optionally otlier bioactive agents described above. This may be similarly done with the second active agent, until a desirable level is attained. Or vice versa, for example in the case of multivitamins and/or minerals, the subject may be stabilized at a desired level of these products and then administered the first active compound. The dose may be increased until a desired and/or optimal effect under the circumstances is reached. In general, the active agent is preferably administered at a concentration that will afford effective results without causing any unduly harmful or deleterious side effects, and may be administered either as a single unit dose, or if desired in convenient subunits administered at suitable times throughout the day. The second therapeutic or diagnostic agent(s) is (are) administered in amounts which are known in the art to be effective for the intended application. In cases where the second agent has an overlapping activity with the principal agent, the dose of one of the other or of both agents may be adjusted to attain a desirable effect without exceeding a dose range wliich avoids untoward side effects. Thus, for example, when other analgesic and anti-inflammatory agents are added to the composition, they may be added in amounts known in the art for their intended application or in doses somewhat lower that when administered by themselves.

Pharmaceutical compositions comprising an anti-sense oligonucleotide as given above effective to reduce expression of an A_! or A₃ adenosine receptor by passing through a cell membrane and binding specifically with mRNA encoding an Ai or A₃ adenosine receptor in the cell so as to prevent its translation are another aspect of the present invention. Such compositions are provided in a suitable pharmaceutically acceptable carrier, e. g., sterile pyrogen-free saline solution. The anti-sense oligonucleotides and the bronchodilators, separately or jointly, may be formulated with a hydrophobic carrier capable of passing through a cell membrane, e. g., in a liposome, with the liposomes carried in a pharmaceutically acceptable aqueous carrier. The oligonucleotides may also be coupled to a substance that inactivates mRNA, such as a ribozyme. Such oligonucleotides may be administered to a subject to inhibit the activation of a target, such as the adenosine receptors, which subject is in need of such treatment for any of the reasons discussed herein. Furthermore, the pharmaceutical formulation may also contain chimeric molecules comprising anti-sense oligonucleotides attached to molecules that are known to be internalized by cells. These oligonucleotide conjugates utilize cellular uptake pathways to increase cellular concentrations of oligonucleotides. Examples of macromolecules used in this manner include transferrin, asialoglycoprotein (bound to oligonucleotides via polylysine) and streptavidin. In the pharmaceutical formulation, the anti-sense compound may be contained within a lipid particle or vesicle, such as a liposome or microcrystal. The particles may be of any suitable structure,

725 such as unilamellar or plurilamellar, so long as the anti-sense oligonucleotide is contained therein. Positively charged lipids such as N- [l-(2, 3 -dioleoyloxy) propyl] -N, N, N-trimethylammoniumethylsulfate, or "DOTAP," are particularly preferred for such particles and vesicles. The preparation of such lipid particles is well known. See, e. g., U.S. Patent Nos. 4,880,635 to Janoff et al.; 4,906,477 to Kurono et al.; 4,911,928 to Wallach; 4,917,951 to Wallach; 4,920,016 to Allen et al.; 4,921,757 to Wheatley et al.; etc.

Subjects may be administered the active composition by any means which transports the anti-sense nucleotide composition to the lung. The anti-sense compounds are particularly disclosed herein may be administered to the lungs of a patient by any suitable means, but are preferably administered by generating an aerosol comprised of respirable particles, the respirable particles comprised of the anti-sense compound, which particles the subject inhales. The respirable particles may be liquid or solid. The particles may optionally contain other therapeutic ingredients. Particles comprised of anti-sense compound for practicing the present invention should include particles of respirable size: that is, particles of a size sufficiently small to pass through the mouth and larynx upon inhalation and into the bronchi and alveoli of the lungs. In general, particles ranging from about 0.05, about 0.1, about 0.5, about 1, about 3, about 6 to about 7, about 8 about 9, about 10 microns in size are respirable. Particles of non-respirable size that are included in the aerosol tend to deposit in the throat and be swallowed, and the quantity of non-respirable particles in the aerosol is preferably minimized. For nasal administration, a particle size in the range of about 8, about 10, about 15, about 20 to 500 μm is preferred to ensure retention in the nasal cavity. Thus, particles of about 4, about 10, about 25, about 50 to about 75, about 100, about 250, about 500 μm and other specific ranges therewithin, are preferred. Others, however, are also contemplated within the confines of this invention.

Liquid pharmaceutical compositions of active compound for producing an aerosol can be prepared by combining the anti-sense compound with a suitable vehicle, such as sterile pyrogen free water. Other therapeutic compounds may optionally be included. Solid particulate compositions containing respirable dry particles of micronized anti-sense compound may be prepared by grinding dry anti-sense compound with a mortar and pestle, and then passing the micronized composition through a 400 mesh screen to break up or separate out large agglomerates. A solid particulate composition comprised of the anti-sense compound may optionally contain a dispersant which serves to facilitate the formation of an aerosol. A suitable dispersant is lactose, which may be blended with the anti-sense compound in any suitable ratio (e. g., a 1 to 1 ratio by weight). Again, other therapeutic compounds may also be included. The dosage of the anti-sense compound administered will depend upon the disease being treated, the condition of the subject, the particular formulation, the route of administration, the timing of administration to a subject, etc. In general, intracellular concentrations of the oligonucleotide of from about 0.01, about 0.05, about 0.1, about 0.2, about 1 to about 5 μM, about 50 μM, about 100 μM or more, and more particularly about 0.2 to about 0.5 μM, are desired. For administration to a subject such as a human, a dosage of from about 0.01, about 0.1 or about 1 mg/Kg up to about 50, about 100, or about 150 mg/Kg and even higher doses are typically employed depending on the route of administration as is known in the art. Depending on the solubility of the particular formulation of active compound administered, the daily dose may be divided among one or several unit dose administrations. Administration of the anti-sense compounds may be carried out therapeutically (i. e., as a rescue treatment) or prophylactically. Aerosols of liquid particles comprising the anti-sense compound may be produced by any suitable means, such as with a nebulizer. See, e. g., U.S. Patent No. 4,501,729. Nebulizers are commercially available devices which transform solutions or suspensions of the active ingredient into a therapeutic aerosol mist either by means of acceleration of a compressed gas, typically air or oxygen, through a narrow venturi orifice or by means of ultrasonic agitation. Suitable formulations for use in nebulizers consist of the active ingredient in a liquid carrier, the active ingredient comprising up to 40% w/w of the formulation, but preferably less than 20% w/w. The carrier is typically water or a dilute aqueous alcoholic solution, preferably made isotonic with body fluids by the addition of, for example, sodium chloride. Optional additives include preservatives if the formulation is not prepared sterile, for example, methyl hydroxybenzoate, antioxidants, flavoring agents, volatile oils, buffering agents and surfactants.

In one preferred embodiment, the pharmaceutical composition comprises nucleic acid(s) that comprise the anti-sense oligo(s) described above, one or more bronchodilating agents, and one or more surfactants along with a carrier and formulation agents. Suitable surfactants or surfactant components for enhancing the uptake of the anti- sense oligonucleotides of the invention include synthetic and natural as well as full and truncated forms of surfactant protein A, surfactant protein B, surfactant protein C, surfactant protein D and surfactant Protein E, di-saturated

726 phosphatidylcholine (other than dipalmitoyl), dipalmitoylphosphatidylcholine, phosphatidylcholine, phosphatidylglycerol, phosphatidylinositol, phosphatidylethanolamine, phosphatidylserine; phosphatidic acid, ubiquinones, lysophosphatidylethanolamine, lysophosphatidylcholine, palmitoyl-lysophosphatidylcholine, dehydroepiandrosterone, dolichols, sulfatidic acid, glycerol-3-phosphate, dihydroxyacetone phosphate, glycerol, glycero-3-phosphocholine, dihydroxyacetone, palmitate, cytidine diphosphate (CDP) diacylglycerol, CDP choline, choline, choline phosphate; as well as natural and artificial lamellar bodies which are the natural carrier vehicles for the components of surfactant, omega-3 fatty acids, polyenic acid, polyenoic acid, lecithin, palmitinic acid, non-ionic block copolymers of ethylene or propylene oxides, polyoxypropylene, monomeric and polymeric, polyoxyethylene, monomeric and polymeric, poly (vinyl amine) with dextran and or alkanoyl side chains, Brij 35, Triton X-100 and synthetic surfactants ALEC, Exosurf, Survan and Atovaquone, among others. These surfactants may be used either as a single, or as part of a multiple component, surfactant in a formulation, or as covalentiy bound additions to the 5' and or 3' ends of the anti-sense oligo(s).

Aerosols of solid particles comprising the active compound may likewise be produced with any solid particulate medicament aerosol generator. Aerosol and spray generators for administering solid particulate medicaments to a subject produce particles that are respirable, as explained above, and generate a volume of aerosol containing a predetermined metered dose of a medicament at a rate suitable for human aάjninistration. One illustrative type of solid particulate aerosol generator is an insufflator. Suitable formulations for administration by insufflation include finely conxrninuted powders that may be delivered by means of an insufflator or taken into the nasal cavity in the manner of a snuff. In the insufflator, the powder (e. g., a metered dose thereof effective to carry out the treatments described herein) is contained in capsules or cartridges, typically made of gelatin or plastic, wliich are either pierced or opened in situ and the powder delivered by air drawn through the device upon inhalation or by means of a manually-operated pump. The powder employed in the insufflator consists either solely of the active ingredient or of a powder blend comprising the active ingredient, a suitable powder diluent, such as lactose, and an optional surfactant. The active ingredient typically comprises from 0.1 to 100 w/w of the formulation. A second type of illustrative aerosol generator comprises a metered dose inhaler. Metered dose inhalers are pressurized aerosol dispensers, typically containing a suspension or solution formulation of the active ingredient in a liquefied propellant. During the use these devices discharge the formulation through a valve adapted to deliver a metered volume, typically from 10:1 to 150:1, to produce a fine particle spray containing the active ingredient. Suitable propellants include certain chlorofluorocarbon compounds, for example, dichlorodifluoromethane, trichlorofluoromethane, dichlorotetrafluoroethane and mixtures thereof. The formulation may additionally contain one or more co-solvents, for example, ethanol, surfactants, such as oleic acid or sorbitan trioleate, antioxidants and suitable flavoring agents. The aerosol, whether formed from solid or liquid particles, may be produced by the aerosol generator for example at a rate of from about 10, about 30, about 70 to about 100, about 150, about 150 liters per minute, more preferably from about 30 to 150 liters per minute, and most preferably about 60 liters per minute. Aerosols containing greater amounts of medicament, however, may be administered more rapidly as is known in the art.

Compositions suitable for oral administration may be presented in discrete units, such as capsules, cachets, lozenges, or tablets, each containing a pre-determined amount of the first and second active compounds; as a powder or granules; as a solution or a suspension in an aqueous or non-aqueous liquid; or as an oil-in-water or water-in-oil emulsion. Such compositions may be prepared by any suitable method of pharmacy that includes the step of bringing into association the active compounds and a suitable carrier. In general, the compositions of the invention are prepared by uniformly and intimately admixing the active compounds with a liquid or finely divided solid carrier, or both, and then, if necessary, shaping the resulting mixture. For example, tablet may be prepared by compressing or molding a powder or granules containing the active compound(s) alone, or optionally with one or more accessory ingredients. Compressed tablets may be prepared by compressing, in a suitable machine, the compound in a free-lowing form, such as a powder or granules optionally mixed with a binder, lubricant, inert diluent, and or surface active/dispensing agent(s) or surfactants. Molded tablets may be made by molding, in a suitable machine, the powdered compound(s) moistened with an inert liquid binder. Compositions for oral administration may optionally include enteric coatings known in the art to prevent degradation of the compositions in the stomach and provide release of the drug in the small intestine.

Compositions suitable for buccal or sub-lingual administration include lozenges comprising the active compound in a flavored base, usually sucrose and acacia or tragacanth, and pastilles comprising the compound in an

727 inert base such as gelatin and glycerin or sucrose and acacia.

Compositions suitable for parenteral administration comprise sterile aqueous and non-aqueous injection solutions, suspensions or emulsions of the active compound, wliich preparations are preferably isotonic with the blood of the intended recipient. These preparations may contain anti-oxidants, buffers, surfactants, bacteriostats, solutes which render the compositions isotonic with the blood of the intended recipient, and other formulation components known in the art. Aqueous and non-aqueous sterile suspensions may include suspending agents and thickening agents. The compositions may be presented in unit-dose or multi-dose containers, for example sealed ampoules and vials, and may be stored in a freeze-dried (lyophilized) condition requiring only the addition of the sterile liquid carrier, for example, saline or water-for-injection immediately prior to use. Extemporaneous injection solutions, suspensions and emulsions may be prepared from sterile powders, granules and tablets of the kind previously described.

Compositions suitable for topical application to the skin preferably take the form of an ointment, cream, lotion, paste, gel, spray, aerosol, or oil, although others are also suitable. Carriers that may be used include vaseline, lanoline, polyethylene glycols, alcohols, transdermal enhancers, and combinations of two or more thereof. Compositions suitable for rectal and vaginal administration are also included and may be prepared by methods known in the art.

Compositions suitable for transdermal administration may be presented as discrete patches adapted to remain in intimate contact with the epidermis of the recipient for a prolonged period of time. Compositions suitable for transdermal administration may also be delivered by iontophoresis. See, e. g. Pharmaceutical Research 3:318 (1986). They typically take the form of an optionally buffered aqueous solution of the active compound containing appropriate ions to facilitate the iontophoretic delivery of the agent.

In one preferred embodiment, the pharmaceutical composition comprises nucleic acid(s) which comprise the anti-sense oligo(s), and/or the glucocorticoid steroid(s) and/or the ubiquinone(s) described above and one or more surfactants. Suitable surfactants or surfactant components for enhancing the uptake of the anti-sense oligonucleotides of the invention include synthetic and natural as well as full and truncated forms of surfactant protein A, surfactant protein B, surfactant protein C, surfactant protein D and surfactant Protein E, di-saturated phosphatidylcholine (other than dipalmitoyl), dipalmitoylphosphatidylcholine, phosphatidylcholine, phosphatidylglycerol, phosphatidylinositol, phosphatidylethanolamine, phosphatidylserine; phosphatidic acid, ubiquinones, lysophosphatidylethanolamine, lysophosphatidylcholine, palmitoyl-lysophosphatidylcholine, dehydroepiandrosterone, dolichols, sulfatidic acid, glycerol-3-phosphate, dihydroxyacetone phosphate, glycerol, glycero-3-phosphocholine, dihydroxyacetone, palmitate, cytidine diphosphate (CDP) diacylglycerol, CDP choline, choline, choline phosphate; as well as natural and artificial lamellar bodies which are the natural carrier vehicles for the components of surfactant, omega-3 fatty acids, polyenic acid, polyenoic acid, lecithin, palmitinic acid, non-ionic block copolymers of ethylene or propylene oxides, polyoxypropylene, monomeric and polymeric, polyoxyethylene, monomeric and polymeric, poly (vinyl amine) with dextran and or alkanoyl side chains, Brij 35, Triton X-100 and synthetic surfactants ALEC, Exosurf, Survan and Atovaquone, among others. These surfactants may be used either as a single, or as part of a multiple component, surfactant in a formulation, or as covalentiy bound additions to the 5' and/or 3' ends of the anti-sense oligo(s). Aerosols of solid particles comprising the active compound may likewise be produced with any solid particulate medicament aerosol generator. One illustrative type of solid particulate aerosol generator is an insufflator. Suitable formulations for aάininistration by insufflation include finely comminuted powders which may be delivered by means of an insufflator or taken into the nasal cavity in the manner of a snuff. In the insufflator, the powder (e. g., a metered dose thereof effective to carry out the treatments described herein) is contained in capsules or cartridges, typically made of gelatin or plastic, which are either pierced or opened in situ and the powder delivered by air drawn through the device upon inhalation or by means of a manually- operated pump. The powder employed in the insufflator consists either solely of the active ingredient or of a powder blend comprising the active ingredient, a suitable powder diluent, such as lactose, and an optional surfactant. The active ingredient typically comprises from 0.1 to 100 w/w of the formulation. A second type of illustrative aerosol generator comprises a metered dose inhaler. Metered dose inhalers are pressurized aerosol dispensers, typically containing a suspension or solution formulation of the active ingredient in a liquefied propellant. During use these devices discharge the formulation through a valve adapted to deliver a metered volume, typically from 10: to 150:1, to produce a fine particle spray containing the active ingredient. Suitable propellants include certain chlorofluorocarbon compounds, for example, dichlorodifluoromethane, trichlorofluoromethane,

728 dichlorotetrafluoroethane and mixtures thereof. The formulation may additionally contain one or more co-solvents, for example, ethanol, surfactants, such as oleic acid or sorbitan trioleate, antioxidants and suitable flavoring agents. The aerosol, whether formed from solid or liquid particles, may be produced by the aerosol generator for example at a rate of from about 10, about 30, about 70 to about 100, about 150, about 150 liters per minute, more preferably from about 30 to 150 liters per minute, and most preferably about 60 liters per minute. Aerosols containing greater amounts of medicament, however, may be administered more rapidly as is known in the art.

The relevant disclosures of all scientific publications and patent references cited in this patent are specifically intended to be incorporated herein by reference, particularly in reference to preparatory methods and technologies which are enabling of the invention. The following examples are provided to illustrate the present invention, and should not be construed as limiting thereon.

EXAMPLES

In the following examples, μM means micromolar, ml means milliliters, μm means micrometers, mm means millimeters, cm means centimeters, °C means degrees Celsius, μg means micrograms, mg means milligrams, g means grams, kg means kilograms, M means molar, and h or hr. means hours. Example 1; Design and Synthesis of Anti-sense Oligonucleotides

The design of anti-sense oligonucleotides against the Ai and A₃ adenosine receptors may require the solution of the complex secondary structure of the target Ai receptor mRNA and the target A₃ receptor mRNA. After generating this structure, anti-sense nucleotide are designed which target regions of mRNA which might be construed to confer functional activity or stability to the mRNA and which optimally may overlap the initiation codon. Other target sites are readily usable. As a demonstration of specificity of the anti-sense effect, other oligonucleotides not totally complementary to the target mRNA, but containing identical nucleotide compositions on a w/w basis, are included as controls in anti-sense experiments.

The mRNA secondary structure of the adenosine Ai receptor was analyzed and used as described above, to design a phosphorothioate anti-sense oligonucleotide. The anti-sense oligonucleotide which was synthesized was designated HAdA,AS and had the following sequence: 5' -GAT GGA GGG CGG CAT GGC GGG-3' ( SEQ ID

NO: 9370). As a control, a mismatched phosphorothioate anti-sense nucleotide designated HAdAlMMl was synthesized with the following sequence: 5' -GTA GCA GGC GGG GAT GGG GGC-3' (SEQ ID NO: 9371). Each oligonucleotide had identical base content and general sequence structure. Homology searches in GENBANK (release 85.0) and EMBL (release 40.0) indicated that the anti-sense oligonucleotide was specific for the human and rabbit adenosine Ai receptor genes, and that the mismatched control was not a candidate for hybridization with any known gene sequence.

The secondary structure of the adenosine A₃ receptor mRNA was similarly analyzed and used as described above to design two phosphorothioate anti-sense oligonucleotides. The first anti-sense oligonucleotide (HAdA3ASl) synthesized had the following sequence: 5' -GTT GTT GGG CAT CTT GCC-3' (SEQ ID NO: 9372). As a control, a mismatched phosphorothioate anti-sense oligonucleotide (HAdA3MMl) was synthesized, having the following sequence: 5' -GTA CTT GCG GAT CTA GGC-3' (SEQ ID NO: 9373). A second phosphorothioate anti-sense oligonucleotide (HAdA3AS2) was also designed and synthesized, having the following sequence: 5' -GTG GGC CTA GCT CTC GCC-3' (SEQ ID NO: 9374). Its control oligonucleotide (HAdA3MM2) had the sequence: 5' -GTC GGG GTA CCT GTC GGC-3' (SEQ ID NO: 9375). Phosphorothioate oligonucleotides were synthesized on an Applied Biosystems Model 396 Oligonucleotide

Synthesizer, and purified using NENSORB chromatography (DuPont, MD).

Example 2: In Vivo Testing of Adenosine A_x

Receptor Anti-sense Oligos

The anti-sense oligonucleotide against the human Aj receptor (SEQ ID NO: 9370) described above, was tested for efficacy in an in vitro model utilizing lung adenocarcinoma cells HTB-54. HTB-54 lung adenocarcinoma cells were demonstrated to express the A] adenosine receptor using standard northern blotting procedures and receptor probes designed and synthesized in the laboratory.

HTB-54 human lung adenocarcinoma cells (106/100 mm tissue culture dish) were exposed to 5.0 :M HAdAlAS or HAdAlMMl for 24 hours, with a fresh change of media and oligonucleotides after 12 hours of

729 incubation. Following 24 hour exposure to the oligonucleotides, cells were harvested and their RNA extracted by standard procedures. A 21-mer probe corresponding to the region of mRNA targeted by the anti-sense (and therefore having the same sequence as the anti-sense, but not phosphorothioated) was synthesized and used to probe northern blots of RNA prepared from HAdAlAS-treated, HAdAlMMl -treated and non-treated HTB-54 cells. These blots showed clearly that HAdAlAS but not HAdAlMMl effectively reduced human adenosine receptor mRNA by

>50%. This result showed that HAdAlAS is a good candidate for an anti-asthma drug since it depletes intracellular mRNA for the adenosine Ai receptor, which is involved in asthma.

Example 3: In Vivo Efficacy of Adenosine Ai

Receptor Anti-sense Oligos A fortuitous homology between the rabbit and human DNA sequences within the adenosine Ai gene overlapping the initiation codon permitted the use of the phosphorothioate anti-sense oligonucleotides initially designed for use against the human adenosine Ai receptor in a rabbit model. Neonatal New Zealand white Pasteurella-free rabbits were immunized intraperitoneally within 24 hours of birth with 312 antigen units/ml house dustmite (D. farinae) extract (Berkeley Biologicals, Berkeley, CA), mixed with 10% kaolin. Immunizations were repeated weekly for the first month and then biweekly for the next 2 months. At 3-4 months of age, eight sensitized rabbits were anesthetized and relaxed with a mixture of ketamine hydrochloride (44 mg/kg) and acepromazine maleate (0.4 mg/kg) administered intramuscularly. The rabbits were then laid supine in a comfortable position on a small molded, padded animal board and intubated with a 4.0-mm intratracheal tube (Mallinkrodt, Inc., Glens Falls, NY). A polyethylene catheter of external diameter 2.4 mm with an attached latex balloon was passed into the esophagus and maintained at the same distance (approximately 16 cm) from the mouth throughout the experiments.

The intratracheal tube was attached to a heated Fleisch pneumotachograph (size 00; DOM Medical, Richmond, VA), and flow was measured using a Validyne differential pressure transducer (Model DP-45161927; Validyne Engineering Corp., Northridge, CA) driven by a Gould carrier amplifier (Model 11-4113; Gould Electronic, Cleveland, OH). The esophageal balloon was attached to one side of the differential pressure transducer, and the outflow of the intratracheal tube was connected to the opposite side of the pressure transducer to allow recording of transpulmonary pressure. Flow was integrated to give a continuous tidal volume, and measurements of total lung resistance (RL) and dynamic compliance (Cdyn) were calculated at isovolumetric and flow zero points, respectively, using an automated respiratory analyzer (Model 6; Buxco, Sharon, CT). Animals were randomized and on Day 1 pretreatment values for PC₅₀ were obtained for aerosolized adenosine. Anti-sense (HAdAlAS) or mismatched control (HAdAlMM) oligonucleotides were dissolved in sterile physiological saline at a concentration of 5000 μg (5 mg) per 1.0 ml. Animals were subsequently administered the aerosolized anti-sense or mismatch oligonucleotide via the intratracheal tube (approximately 5000 μg in a volume of 1.0 ml), twice daily for two days. Aerosols of either saline, adenosine, or anti-sense or mismatch oligonucleotides were generated by an ultrasonic nebulizer (DeVilbiss, Somerset, PA), producing aerosol droplets 80% of which were smaller than 5 :m in diameter. In the first arm of the experiment, four randomly selected allergic rabbits were administered anti-sense oligonucleotide and four the mismatched control oligonucleotide. On the morning of the third day, PC₅₀ values (the concentration of aerosolized adenosine in mg/ml required to reduce the dynamic compliance of the bronchial airway 50% from the baseline value) were obtained and compared to PC₅₀ values obtained for these animals prior to exposure to oligonucleotide. Following a 1 week interval, animals were crossed over, with those previously administered mismatch control oligonucleotide now administered anti-sense oligonucleotide, and those previously treated with anti-sense oligonucleotide now administered mismatch control oligonucleotide. Treatment methods and measurements were identical to those employed in the first arm of the experiment. It should be noted that in six of the eight animals treated with anti-sense oligonucleotide, adenosine-mediated bronchoconstriction could not be obtained up to the limit of solubility of adenosine, 20 mg/ml. For the purpose of calculation, PC₅₀ values for these animals were set at 20 mg/ml. The values given therefore represent a minimum figure for anti-sense effectiveness. Actual effectiveness was higher. The results of this experiment are illustrated in Table 5 below.

Table 5: Effect of Adenosine Ai Receptor Anti-sense Oligo u on PC50 Values in Asthmatic Ra

730

In both arms of the experiment, animals receiving the anti-sense oligonucleotide showed an order of magnitude increase in the dose of aerosolized adenosine required to reduce dynamic compliance of the lung by 50%.

No effect of the mismatched control oligonucleotide upon PC₅₀ values was observed. No toxicity was observed in any animal receiving either anti-sense or control inhaled oligonucleotide. These results show clearly that the lung has exceptional potential as a target for anti-sense oligonucleotide-based therapeutic intervention in lung disease. They further show, in a model system which closely resembles human asthma, that downregulation of the adenosine Ai receptor largely eliminates adenosine-mediated bronchoconstriction in asthmatic airways. Bronchial hyperresponsiveness in the allergic rabbit model of human asthma is an excellent endpoint for anti-sense intervention since the tissues involved in this response lie near to the point of contact with aerosolized oligonucleotides, and the model closely simulates an important human disease.

Example 4: Specificity of A adenosine Receptor Anti-sense Oligonucleotide At the conclusion of the cross-over experiment of Example 3 above, airway smooth muscle from all rabbits was quantitatively analyzed for adenosine Ai receptor number. As a control for the specificity of the anti-sense oligonucleotide, adenosine A₂ receptors, which should not have been affected, were also quantified. Airway smooth muscle tissue was dissected from each rabbit and a membrane fraction prepared according to the method of Kleinstein et al. (Kleinstein, J. and Glossmann, H., Naunyn-Schmiedeberg's Arch. Pharmacol. 305: 191-200 (1978)), the relevant portion of which is hereby incorporated in its entirety by reference, with slight modifications.

Crude plasma membrane preparations were stored at -70EC until the time of assay. Protein content was determined by the method of Bradford (M. Bradford, Anal. Biochem. 72, 240-254 (1976), the relevant portion of which is hereby incorporated in its entirety by reference). Frozen plasma membranes were thawed at room temperature and were incubated with 0.2 U/ml adenosine deaminase for 30 minutes at 37EC to remove endogenous adenosine. The binding of [³H] DPCPX (A_t receptor-specific) or [³H] CGS-21680 (A_t receptor-specific) was measured as previously described by Ali et al. (Ali, S. et al, J. Pharmacol. Exp. Ther. 268, Am. J. Physiol 266, L271-277 (1994), the relevant portion of which is hereby incorporated in its entirety by reference). The animals treated with adenosine Ai anti-sense oligonucleotide in the cross-over experiment had a nearly 75% decrease in Ai receptor number compared to controls, as assayed by specific binding of the A specific antagonist DPCPX. There was no change in adenosine A₂ receptor number, as assayed by specific binding of the A₂ receptor-specific agonist 2- [p- (2- carboxyethyl)-phenethylamino] -5' - (N-ethylcarboxamido) adenosine (CGS-21680). This is illustrated in Table 6 below.

Table 6: Specificity of Action of Adenosine Ai Receptor Oligonucleotide Anti-sense

Mismatch Control Ai Anti-sense Oligonucleotide Oligonucleotide

A Specific Binding 1105 ± 48** 293 ± 18

A₂-Specific Binding 302 ± 22 442 ± 171

The results are presented as the mean (n = 8) ± SEM.

The significance was determined by repeated-measures analysis of variance (ANOVA), and Tukey's protected test.

"Significantly different from mismatch control, p<0.01.

The above results illustrate the effectiveness of anti-sense oligonucleotides in treating airway disease. Since the anti-sense oligos described above, eliminate the receptor systems responsible for adenosine-mediated bronchoconstriction, it may be less imperative to eliminate adenosine from them. However, it would be preferable to eliminate adenosine from even these oligonucleotides to reduce the dose needed to attain a similar effect. Described above are other anti-sense oligonucleotides targeting mRNA of proteins involved in inflammation. Adenosine has been eliminated from their nucleotide content to prevent its liberation during degradation.

Example 5: Anti-sense Oligos directed to other Target Nucleic Acids

This work was conducted to demonstrate that the present invention is broadly applicable to anti-sense oligonucleotides ("oligos") specific to nucleic acid targets broadly. The following experimental studies were conducted to show that the method of the invention is broadly suitable for use with anti-sense oligos designed as

731 taught by this application and targeted to any and all adenosine receptor mRNAs. For this purpose, various anti- sense oligos were porepared to adenosine receptor mRNAs exemplified by the adenosine A_1; A_2b and A₃ receptor mRNAs. Anti-sense Oligo I was disclosed above (SEQ D NO:9370).Five additional anti-sense phosphorothioate oligos were designed and synthesized as indicated above. 1- Oligo II (SEQ ID NO: 9376) also targeted to the adenosine A_! receptor, but to a different region than Oligo I.

2- Oligo V (SEQ ID NO: 9379) targeted to the adenosine A_2b receptor.

3- Oligos III (SEQ ID NO: 9377) and IV (SEQ ID NO: 9378) targeted to different regions of the adenosine A₃ receptor.

4- Oligo I-PD (SEQ ID NO: 11050)(a phosphodiester oligo of the same sequence as Oligo I).

These anti-sense oligos were designed for therapy on a selected species as described above and are generally specific for that species, unless the segment of the target mRNA of other species happens to contain a similar sequences. All anti-sense oligos were prepared as described below, and tested in vivo in a rabbit model for bronchoconstriction, inflammation and allergy, which have breathing difficulties and impeded lung airways, as is the case in ailments such as asthma, as described in the above-identified application.

Example 6: Design & Sequences of other Anti-sense Oligos Six oligos and their effects in a rabbit model were studied and the results of these studies are reported and discussed below. Five of these oligos were selected for this study to complement the data on Oligo I (SEQ ID NO:

9370) provided in Examples 1 to 4 above. This oligo is anti-sense to one region of the adenosine Ai receptor mRNA. The oligos tested are identified as anti-sense Oligos I (SEQ ID NO: 9370) and II (SEQ H) NO: 9376) targeted to a different region of the adenosine Ai receptor mRNA, Oligo V (SEQ ID NO:9377) targeted to the adenosine A_2b receptor mRNA, and anti-sense Oligos III and IV (SEQ ID NOS: 9378and 9379) targeted to two different regions of the adenosine A₃ receptor mRNA. The sixth oligo (Oligo I-PD) is a phosphodiester version of

Oligo I (SEQ ID NO:9370). The design and synthesis of these anti-sense oligos was performed in accordance with

Example 1 above.

(I) Anti-sense Oligo I The anti-sense oligonucleotide I referred to in Examples 1 to 4 above is targeted to the human Ai adenosine receptor mRNA (EPI 2010). Anti-sense oligo I is 21 nucleotide long, overlaps the initiation codon, and has the following sequencer '-GAT GGA GGG CGG CAT GGC GGG-3'(SEQ ID NO: 9370). The oligo I was previously shown to abrogate the adenosine-induced bronchoconstriction in allergic rabbits, and to reduce allergen-induced airway obstruction and bronchial hyperresponsiveness (BHR), as discussed above and shown by Nyce, J. W. & Metzger, W. J., Nature, 385:721 (1977), the relevant portions of which reference are incorporated in their entireties herein by reference.

(II) Anti-sense Oligo II

A phosphorothioate anti-sense oligo (SEQ ID NO: 9376) was designed in accordance with the invention to target the rabbit adenosine Ai receptor mRNA region +936 to +956 relative to the initiation codon (start site). The anti-sense oligo II is 21 nucleotide long, and has the following sequence: 5'-CTC GTC GCC GTC GCC GGC

GGG-3' (SEQ ID NO: 9376).

(III) Anti-sense Oligo III

A phosphorothioate anti-sense oligo other than that provided in Example 1 above (SEQ ID NO: 9377) was designed in accordance with the invention to target the anti-sense A₃ receptor mRNA region +3 to + 22 relative to the initiation codon start site. The anti-sense oligo III is 20 nucleotide long, and has the following sequence: 5'-

GGG TGG TGC TAT TGT CGG GC-3' (SEQ ID NO: 9377).

(IV) Anti-sense Oligo IV

Yet another phosphorothioate anti-sense oligo (SEQ ID NO: 9378) was designed in accordance with the invention to target the adenosine A₃ receptor mRNA region + 386 to + 401 relative to the initiation codon (start site). The anti-sense oligo IV is 15 nucleotide long, and has the following sequence: 5'-GGC CCA GGG CCA

GCC-3' (SEQ ID NO: 9378)

(V) Anti-sense Oligo V

A phosphorothioate anti-sense oligo (SEQ ID NO: 9379) was designed in accordance with the invention to target the adenosine A_2b receptor mRNA region -21 to -1 relative to the initiation codon (start site). The anti-sense oligonucleotide V is 21 nucleotide long, and has the following sequence: 5'-GGC CGG GCC AGC CGG GCC

CGG-3' (SEQ DD NO: 9379).

(VI) Ai Mismatch Oligos

732 Two different mismatched oligonucleotides having the following sequences were used as controls for anti- sense oligo I(SEQ ID NO: 9370) described in Example 5 above: Aι MM2:5'-GTA GGT GGC GGG CAA GGC GGG-3' (SEQ ID NO: 12490), and Ai MM3:5'-GAT GGA GGC GGG CAT GGC GGG-3' (SEQ ID NO:

12489). Anti-sense oligo I and the two mismatch anti-sense oligos had identical base content and general sequence structure. Homology searches in GENBANK (release 85.0) and EMBL (release 40.0) indicated that the anti-sense oligo I was specific, not only for the human, but also for the rabbit, adenosine Ai receptor genes, and that the mismatched controls were not candidates for hybridization with any known human or animal gene sequence. (VII) Anti-sense Oligo A PD (Oligo VI)

A phosphodiester anti-sense oligo (Oligo VT; SEQ ID NO: 9370) having the same nucleotide sequence as Oligo I was designed as disclosed in the above-identified application. Anti-sense oligo I-PD is 21 nucleotide long, overlaps the initiation codon, and has the following sequence: 5'- GAT GGA GGG CGG CAT GGC GGG-3' (SEQ ID NO: 9370). Ill) Controls

Each rabbit was administered 5.0 ml aerosolized sterile saline following the same schedule as for the anti- sense oligos in (II), (III), and (IV) above.

Example 7: Synthesis of Anti-sense Oligos

Phosphorothioate anti-sense oligos having the sequences described in (a) above, were synthesized on an

Applied Biosystems Model 396 Oligonucleotide Synthesizer, and purified using NENSORB chromatography

(DuPont, DE). TETD (tetraethyltliiuram disulfide) was used as the sulfurizing agent during the synthesis. Anti- sense oligonucleotide II (SEQ ID NO: 9376), anti-sense oligonucleotide III (SEQ ID NO: 9377) and anti-sense oligonucleotide IV (SEQ ID NO: 9378) were each synthesized and purified in this manner.

Example 8: Preparation of Allergic Rabbits

Neonatal New Zealand white Pasturella-free rabbits were immunized intraperitoneally within 24 hours of birth with 0.5 ml of 312 antigen units/ml house dust mite (D.farinae) extract (Berkeley Biologicals, Berkeley, CA) mixed with 10% kaolin as previously described (Metzger, W. J., in Late Phase Allergic Reactions, Dorsch, W., Ed.,

CRC Handbook, pp. 347-362, CRC Press, Boca Raton (1990); Ali, S., Metzger, W. J. and Mustafa, S. J., Am. J. Resp. Crit. Care Med. 149: 908 (1994)), the relevant portions of which are incorporated in their entireties here by reference. Immunizations were repeated weekly for the first month and then biweekly until the age of 4 months. These rabbits preferentially produce allergen-specific IgE antibody, typically respond to aeroallergen challenge with both an early and late-phase asthmatic response, and show bronchial hyper responsiveness (BHR). Monthly intraperitoneal administration of allergen (312 units dust mite allergen, as above) continues to stimulate and maintain allergen-specific IgE antibody and BHR. At 4 months of age, sensitized rabbits were prepared for aerosol administration as described by Ali et al. (Ali, S., Metzger, W. J. and Mustafa, S. J., Am. J. Resp. Crit. Care Med. 149 (1994)), the relevant section being incorporated in its entirety here by reference. DOSE-RESPONSE STUDIES

Example 9: Experimental Setup

Aerosols of either adenosine (0-20 mg/ml), or anti-sense or one of two mismatch oligonucleotides (5 mg/ml) were separately prepared with an ultrasonic nebulizer (Model 646, DeVilbiss, Somerset, PA), which produced aerosol droplets, 80% of which were smaller than 5μm in diameter. Equal volumes of the aerosols were administered directly to the lungs via an intratracheal tube. The animals were randomized, and administered aerosolized adenosine. Day 1 pre-treatment values for sensitivity to adenosine were calculated as the dose of adenosine causing a 50% loss of compliance (PC₅₀ Adenosine). The animals were then administered either the aerosolized anti-sense or one of the mismatch anti-sense oligos via the intratracheal tube (5 mg/1.0 ml), for 2 minutes, twice daily for 2 days (total dose, 20 mg). Post-treatment PC₅₀ values were recorded (post-treatment challenge) on the morning of the third day. The results of these studies are provided in Example 21 below.

Example 10: Crossover Experiments

For some experiments utilizing anti-sense oligo I (SEQ DD NO: 9370) and a corresponding mismatch control oligonucleotide AιMM2, following a 2 week interval, the ariimals were crossed over, with those previously administered the mismatch control AιMM2, now receiving the anti-sense oligo I, and those previously treated with the anti-sense oligo I, now receiving the mismatch control AιMM2 oligo. The number of animals per group was as

733 follows. For mismatch A_tMM2 (Control 1), n=7, since one animal was lost in the second control arm of the experiment due to technical difficulties, for mismatch AιMM3 n=4 (Control 2) and for AiAS anti-sense oligo I, n=8. The AιMM3 oligo-treated animals were analyzed separately and were not part of the cross-over experiment. The treatment methods and measurements employed following the cross-over were identical to those employed in the first arm of the experiment. In 6 of the 8 animals treated with the anti-sense oligo I (SEQ DD NO: 9370), no PC₅₀ value could be obtained for adenosine doses of up to 20 mg/ml, wliich is the limit of solubility of adenosine. Accordingly, the PC₅₀ values for these animals were assumed to be 20 mg/ml for calculation purposes. The values given, therefore, represent a minimum figure for the effectiveness of the anti-sense oligonucleotides of the invention. Other groups of allergic rabbits (n=4 for each group) were administered 0.5 or 0.05 mg doses of the anti-sense oligo I (SEQ DD NO: 9370), or the AιMM2 oligo in the manner and according to the schedule described above (the total doses being 2.0 or 0.2 mg). The results of these studies are provided in Example 22 below.

Example 11: Anti-sense Oligo Formulation

Each one of anti-sense oligos were separately solubilized in an aqueous solution and administered as described for anti-sense oligo I (SEQ ID NO: 9370) in (e) above, in four 5 mg aliquots (20 mg total dose) by means of a nebulizer via endotracheal tube, as described above. The results obtained for anti-sense oligo I and its mismatch controls confirmed that the mismatch controls are equivalent to saline, as described in Example 19 below and in Table 1 of Nyce & Metzger, Nature 385: 721-725 (1997). Because of this finding, saline was used as a control for pulmonary function studies employing anti-sense oligos II, III and IV (SEQ ID NOS: 9376, 9377 and 9378). Example 12: Specificity of Oligo I for Adenosine A_t Receptor (Receptor Binding Studies)

Tissue from airway smooth muscle was dissected to primary, secondary and tertiary bronchi from rabbits which had been administered 20 mg oligo I (SEQ ID NO: 9370) in 4 divided doses over a period of 48 hours as described above. A membrane fraction was prepared according to the method of Ali et al. (Ali, S., et al., Am. J. Resp. Crit. Care Med. 149: 908 (1994), the relevant section relating to the preparation of the membrane fraction is incorporated in its entirety hereby by reference). The protein content was determined by the method of Bradford and plasma membranes were incubated with 0.2 U/ml adenosine deaminase for 30 minutes at 37EC to remove endogenous adenosine. See, Bradford, M. M. Anal. Biochem. 72, 240-254 (1976), the relevant portion of which is hereby incorporated in its entirety by reference. The binding of [³H]DPCPX, [³H]NPC17731, or [³H]CGS-21680 was measured as described by Jarvis et al. See, Jarvis, M.F., et al., Pharmacol. Exptl. Ther. 251, 888-893 (1989), the relevant portion of which is fully incorporated herein by reference. The results of this study are shown in Table 8 and discussed in Example 20 below.

Example 13: Pulmonary Function Measurements (Compliance c_DYN and Resistance)

At 4 months of age, the immunized animals were anesthetized and relaxed with 1.5 ml of a mixture of ketamine HCl (35 mg/kg) and acepromazine maleate (1.5 mg/kg) administered intramuscularly. After induction of anesthesia, allergic rabbits were comfortably positioned supine on a soft molded animal board. Salve was applied to the eyes to prevent drying, and they were closed. The animals were then intubated with a 4.0 mm intermediate high- low cuffed Murphy 1 endotracheal tube (Mallinckrodt, Glen Falls, NY), as previously described by Zavala and Rhodes. See, Zavala and Rhodes, Proc. Soc. Exp. Biol. Med. 144: 509-512 (1973), the relevant portion of which is incorporated herein by reference in its entirety. A polyethylene catheter of OD 2.4 mm (Becton Dickinson, Clay

Adams, Parsippany NJ) with an attached thin-walled latex balloon was passed into the esophagus and maintained at the same distance (approximately 16 cm) from the mouth throughout the experiment. The endotracheal tube was attached to a heated Fleisch pneumotach (size 00; DEM Medical, Richmond, VA), and the flow (v) measured using a Validyne differential pressure transducer (Model DP-45-16-1927, Validyne Engineering, Northridge, CA), driven by a Gould carrier amplifier (Model 11-4113, Gould Electronics, Cleveland, OH). An esophageal balloon was attached to one side of the Validyne differential pressure transducer, and the other side was attached to the outflow of the endotracheal tube to obtain transpulmonary pressure (P^). The flow was integrated to yield a continuous tidal volume, and the measurements of total lung resistance (R_t) and dynamic compliance (C_dyn) were made at isovolumetric and zero flow points. The flow, volume and pressure were recorded on an eight channel Gould 2000 W high-frequency recorder and C_dyn was calculated using the total volume and the difference in P_tp at zero flow, and

. R_t was calculated as the ratio of Ptp and V at midtidal lung volumes. These calculations were made automatically

734 with the Buxco automated pulmonary mechanics respiratory analyzer (Model 6, Buxco Electronics, Sharon, CT), as previously described by Giles et al. See, Giles et al., Arch. Int. Pharmacodyn. Ther. 194: 213-232 (1971), the relevant portion of which describing these calculations is incorporated in toto hereby by reference. The results obtained upon administration of oligo II on allergic rabbits are shown and discussed in Example 26 below. Example 14: Measurement of Bronchial Hyperresponsiveness (BBR)

Each allergic rabbit was administered Mstamine by aerosol to determine their baseline hyperresponsiveness. Aerosols of either saline or histamine were generated using a DeVilbiss nebulizer (DeVilbiss, Somerset, PA) for 30 seconds and then for 2 minutes at each dose employed. The ultrasonic nebulizer produced aerosol droplets of wliich 80% were <5 micron in diameter. The mstamine aerosol was administered in increasing concentrations (0.156 to 80 mg/ml) and measurements of pulmonary function were made after each dose. The B4R was then determined by calculating the concentration of histamine (mg/ml) required to reduce the _yn 50% from baseline (PC₅₀ Histamine)-

Example 15: Cardiovascular Effect of Anti-sense Oligo I

The measurement of cardiac output and other cardiovascular parameters using CardiomaxJ utilizes the principal of thermal dilution in which the change in temperature of the blood exiting the heart after a venous injection of a known volume of cool saline is monitored. A single rapid injection of cool saline was made into the right atrium via carrnulation of the right jugular vein, and the corresponding changes in temperature of the mixed injectate and blood in the aortic arch were recorded via cannulation of the carotid artery by a temperature-sensing miniprobe. Twelve hours after the allergic rabbits had been treated with aerosols of oligo I (EPI 2010; SEQ ID NO: 9370) as described in (d) above, the animals were anesthetized with 0.3 ml/kg of 80% Ketamine and 20% Xylazine.

This time point coincides with previous data showing efficacy for SEQ ID NO: 9370, as is clearly shown by Nyce & Metzger, (1997), supra, the pertinent disclosure being incoφorated in its entirety here by reference. A thermocouple was then inserted into the left carotid artery of each rabbit, and was then advanced 6.5 cm and secured with a silk ligature. The right jugular vein was then cannulated and a length of polyethylene tubing was inserted and secured. A thermodilution curve was then established on a CardiomaxJ II (Columbus Instruments, Ohio) by injecting sterile saline at 20EC to determine the correctness of positioning of the thermocouple probe. After establishing the correctness of the position of the thermocouple, the femoral artery and vein were isolated. The femoral vein was used as a portal for drug injections, and the femoral artery for blood pressure and heart rate measurements. Once constant baseline cardiovascular parameters were established, CardiomaxJ measurements of blood pressure, heart rate, cardiac output, total peripheral resistance, and cardiac contractility were made.

Example 16: Duration of Action of Oligo I (SEQ ID NO: 9370)

Eight allergic rabbits received initially increasing log doses of adenosine by means of a nebulizer via an intra-tracheal tube as described in (f) above, beginning with 0.156 mg/ml until compliance was reduced by 50% (PC_{50 Adenos}i_ne) to establish a baseline. Six of the rabbits then received four 5 mg aerosolized doses of (SEQ ID NO: 9370) as described above. Two rabbits received equivalent amounts of saline vehicle as controls. Beginning 18 hours after the last treatment, the PC_{50 Adenos}i_ne values were tested again. After this point, the measurements were continued for all animals each day, for up to 10 days. The results of this study are discussed in Example 25 below.

Example 17: Reduction of Adenosine A_2b Receptor Number by Anti-sense Oligo V Sprague Dawley rats were administered 2.0 mg respirable anti-sense oligo V (SEQ ID NO: 9379) three times over two days using an inhalation chamber as described above. Twelve hours after the last administration, lung parenchymal tissue was dissected and assayed for adenosine A_2b receptor binding using [311]-NECA as described by Nyce & Metzger (1997), supra. Controls were conducted by administration of equal volumes of saline. The results are significant at p<0.05 using Student's paired t test, and are discussed in Example 28 below. Example 18: Comparison of Oligo I & Corresponding

Phosphodiester Oligo VI (SEQ DD NO: 11050)

Oligo I (SEQ ID NO: 9370) countered the effects of adenosine and eliminated sensitivity to it for adenosine amounte up to 20 mg adenosine/5.0 ml (the limit of solubility of adenosine). Oligo VI (SEQ DD NO:

11050), the phosphodiester version of the oligonucleotide sequence, was completely ineffective when tested in the same manner. Both compounds have identical sequence, differing only in the presence of phosphorothioate residues in Oligo I (SEQ ID NO: 9370), and were delivered as an aerosol as described above and in Nyce & Metzger

735 (1997), supra. Significantly different at p<0.001, Student's paired t test. The results are discussed in Example 29 below.

RESULTS OBTAINED FOR ANTI-SENSE OLIGO I (SEQ ID NO: 9370)

Example 19: Results of Prior Work

The nucleotide sequence and other data for anti-sense oligo I (SEQ DD NO: 9370), which is specific for the adenosine Ai receptor, were provided above. The experimental data showing the effectiveness of oligo I in down regulating the receptor number and activity were also provided above. Further information on the characteristics and activities of anti-sense oligo I is provided in Nyce, J. W. and Metzger, W. J., Nature 385:721 (1997), the relevant parts of which relating to the following results are incoφorated in their entireties herein by reference. The Nyce & Metzger (1997) publication provided data showing that the anti-sense oligo I (SEQ ID NO: 9370):

(1) The anti-sense oligo I reduces the number of adenosine Ai receptors in the bronchial smooth muscle of allergic rabbits in a dose-dependent manner as may be seen in Table 5 below.

(2) Anti-sense Oligo I attenuates adenosine-induced bronchoconstriction and allergen-induced bronchoconstriction.

(3) The Oligo I attenuates bronchial hyperresponsiveness as measured by PC₅₀ histamine, a standard measurement to assess bronchial hyperresponsiveness. This result clearly demonstrates anti- inflammatory activity of the anti-sense oligo I as is shown in Table 5 above.

(4) As expected, because it was designed to target it, the anti-sense oligo I is totally specific for the adenosine Ai receptor, and has no effect at all at any dose on either the very closely related adenosine A₂ receptor or the related bradykinin B₂ receptor. This is seen in Table 5 below.

(5) In contradistinction to the above effects of the Oligo I, the mismatch control molecules MM2 and MM3 (SEQ ID NO: 11051 and SEQ ID NO: 11052) which have identical base composition and molecular weight but differed from the anti-sense oligo I (SEQ DD NO: 9370) by 6 and 2 mismatches, respectively. These mismatches, which are the minimum possible while still retaining identical base composition, produced absolutely no effect upon any of the targeted receptors (Ai, A₂ or B₂).

These results, along with a complete lack of prior art on the use of anti-sense oligonucleotides, such as oligo I, targeted to the adenosine Ai receptor, are unexpected results. The showings presented in this patent clearly enable and demonstrate the effectiveness, for their intended use, of the claimed agents and method for treating a disease or condition associated with lung airway, such as bronchoconstriction, inflammation, allergy(ies), and the like.

Example 20: Oligo I Significantly Reduces

Response to Adenosine Challenge

The receptor binding experiment is described in Example 12 above, and the results shown in Table 5 below which shows the binding characteristics of the adenosine A selective ligand [³H]DPCPX and the bradylάnin B₂- selective ligand [³H]NPC 17731 in membranes isolated from airway smooth muscle of Ai adenosine receptor and B₂ bradykinin receptor anti-sense- and mismatch-treated allergic rabbits.

Table 5: Binding Characteristics of Three Anti-Sense Oligos

Treatment¹ Ai receptor B₂ receptor

Kd B_max Kd Bmax

Adenosine A_x Receptor

20 mg 0.36±0.029 nM 19+1.52 fmoles* 0.39+0.031 nM 14.8±0.99fmoles

2 mg 0.38+0.030 nM 32±2.56 fmoles* 0.41+0.028 nM 15.5+1.08

0.2 mg 0.37±0.030 nM 49±3.43 fmoles 0.34+0.024 nM 15.0+1.06

AiMMl (Control)

20 mg 0.34±0.027 nM 52.0+3.64 fmoles 0.35+0.024 nM 14.0± 1.0 fmoles

2 mg 0.37±0.033 nM 51.8+3.88 fmoles 0.38+0.028 nM 14.6+1.02

B₂A (Bradykinin Receptor)

20 mg 0.36±0.028 nM 45.0+3.15 fmoles 0.38+0.027 nM 8.7±0.62

2 mg 0.39±0.035 nM 44.3+2.90 fmoles 0.34+0.024 nM 11.9±0.76

736 0.2 mg 0.40+0.028 nM 47.0±3.76 fmoles 0.35±0.028 nM 15.1+1.05

B₂MM (Control)

20 mg 0.39+0.031 nM 42.0±2.94 finoles 0.41+0.029 nM 14.0+0.98

2 mg 0.41+0.035 nM 40.0±3.20 fmoles 0.37+0.030 nM 14.8+0.99

0.2 mg 0.37±0.029 nM 43.0±3.14 fmoles 0.36+0.025 nM 15.1+1.35

Saline Control 0.37±0.041 46.0±5.21 0.39+0.047 nM 14.2+1.35

¹ Refers to total oligo administered in four equivalently divided doses over a 48 hour period. Treatments and analyses were performed as described in methods. Significance was determined by repeated-measures analysis of variance (ANOVA), and Tukey's protected t test, n = 4-6 for all groups.

* Significantly different from mismatch control- and saline-treated groups, p<0.001 ; """Significantly different from mismatch control- and saline-treated groups, p<0.05.

Example 21: Dose-response Effect of Oligo I

Anti-sense oligo I (SEQ ID NO: 9370) was found to reduce the effect of adenosine administration to the animal in a dose-dependent manner over the dose range tested as shown in Table 6 below. Table 6: Dose-Response Effect to Anti-sense Oligo I Total Dose PC₅₀ Adenosine (mg^") (mg Adenosine^')

Anti-sense Oligo I

0.2 8.32+7.2

2.0 14.0+7.2 20 19.5+0.34

A_XMM2 oligo (control)

0.2 2.51+0.46

2.0 3.13+ 0.71 20 3.25+ 0.34 The above results were studied with the Student's paired t test and found to be statistically different. p=0.05

The oligo I (SEQ ID NO: 9370), an anti-adenosine Ai receptor oligo, acts specifically on the adenosine Ai receptor, but not on the adenosine A₂ receptors. These results stem from the treatment of rabbits with anti-sense oligo I (SEQ ID NO: 9370) or mismatch control oligo (SEQ DD NO: 11051; AιMM2) as described in Example 9 above and in Nyce & Metzger (1997), supra (four doses of 5 mg spaced 8 to 12 hours apart via nebulizer via endotracheal tube), bronchial smooth muscle tissue excised and the number of adenosine Ai and adenosine A₂ receptors determined as reported in Nyce & Metzger (1997), supra.

Example 22: Specificity of Oligo I (SEQ DD NO: 9370) for Target Gene Product Oligo I (SEQ DD NO: 9370) is specific for the adenosine Ai receptor whereas its mismatch controls had no activity. Figure 1 depicts the results obtained from the cross-over experiment described in Example 10 above and in Nyce & Metzger (1997), supra. The two mismatch controls (SEQ ID NO: 11051 and SEQ ID NO: 11052) evidenced no effect on the PC_{50 Adenos}i_ne value. On the contrary, the administration of anti-sense oligo I (SEQ DD NO: 9370) showed a seven-fold increase in the PC_{50 Adenos}i_ne value. The results clearly indicate that the anti-sense oligo I (SEQ ID NO: 9370) reduces the response (attenuates the sensitivity) to exogenously administered adenosine when compared with a saline control. The results provided in Table 6 above clearly establish that the effect of the anti-sense oligo I is dose dependent (see, column 3 of Table 5). The Oligo I was also shown to be totally specific for the adenosine Ai receptor, (see, top 3 rows of Table), inducing no activity at either the closely related adenosine A₂ receptor or the bradykin i B₂ receptor (see, lines 8-10 of Table 6 above). In addition, the results shown in Table 6 establish that the anti-sense oligo I (SEQ DD NO: 9370) decreases sensitivity to adenosine in a dose dependent manner, and that it does this in an anti-sense oligo-dependent manner since neither of two mismatch control oligonucleotides (A_:MM2; SEQ ID NO: 11051 and A_tMM3; SEQ DD NO: 11052) show any effect on PC_{50 A enos}i_ne values or on attenuating the number of adenosine Ai receptors.

Example 23: Effect on Aeroallergen-induced Bronchoconstriction & Inflammation

737 The Oligo I (SEQ DD NO: 9370) was shown to sigmficantly reduce the stamine-induced effect in the rabbit model when compared to the mismatch oligos. The effect of the anti-sense Oligo I (SEQ DD NO: 9370) and the mismatch oligos (AιMM2, SEQ ID NO: 11051and AιMM3, SEQ DD NO: 11051) on allergen-induced airway obstruction and bronchial hyperresponsiveness was assessed in allergic rabbits. The effect of the anti-sense oligo I (SEQ ID NO: 9370) on allergen-induced airway obstruction was assessed. As calculated from the area under the plotted curve, the anti-sense oligo I significantly inhibited allergen-induced airway obstruction when compared with the mismatched control (55%, p<0.05; repeated measures ANOVA, and Tukey's t test). A complete lack of effect was induced by the mismatch oligo AιMM2 (Control) on allergen induced airway obstruction. The effect of the anti-sense oligo I (SEQ ID NO: 9370 on allergen-induced BHR was determined as above. As calculated from the PC_{50 H}i_stami_ne value , the anti-sense oligo I (SEQ ID NO: 9370) significantly inhibited allergen-induced BHR in allergic rabbits when compared to the mismatched control (61%, p<0.05; repeated measures ANOVA, Tukey's t test). A complete lack of effect of the AiMM mismatch control on allergen-induced BHR was observed. The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ DD NO: 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ ID NO: 9370). The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ ID NO: 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ DD NO: 9370). The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ ID NO: 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ DD NO: 9370). The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ ID NO: 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity wliich indicates anti- inflammatory activity for anti-sense oligo I (SEQ ID NO: 9370). The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ ID NO: 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ ID NO: 9370). The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ ID NO: 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ DD NO: 9370). The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ DD NO: 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ ID NO: 9370). The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ DD NO: 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ DD NO: 9370). The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ DD NO: 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity wliich indicates anti- inflammatory activity for anti-sense oligo I (SEQ ID NO: 9370). The results indicated that anti-sense oligo I (SEQ DD NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ DD NO: 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine

738 sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ DD NO: 9370). The results indicated that anti-sense oligo I (SEQ ID NO: 93.70) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ ID NO: 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ ID NO: 9370). The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ DD NO: 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon Mstamine sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ ID NO; 9370).The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ ID NO; 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ ID NO; 9370).The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ ID NO; 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ ID NO; 9370). The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ ID NO; 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ ID NO; 9370).The results indicated that anti-sense oligo I (SEQ ID NO: 9370) is effective to protect against aeroallergen-induced bronchoconstriction (house dust mite). In addition, the anti-sense oligo I (SEQ ID NO; 9370) was also found to be a potent inhibitor of dust mite-induced bronchial hyper responsiveness, as shown by its effects upon histamine sensitivity which indicates anti- inflammatory activity for anti-sense oligo I (SEQ DD NO; 9370).

Example 24: Anti-sense Oligo I is Free of Deleterious Side Effects The Oligo I (SEQ DD NO: 9370) was shown to be free of side effects that might be toxic to the recipient. No changes in arterial blood pressure, cardiac output, stroke volume, heart rate, total peripheral resistance or heart contractility (dPdT) were observed following administration of 2.0 or 20 mg oligo I (SEQ DD NO: 9370). The addition, the results of the measurement of cardiac output (CO), stroke volume (SV), mean arterial pressure (MAP), heart rate (HR), total peripheral resistance (TPR), and contractility (dPdT) with a CardiomaxJ apparatus (Columbus Instruments, Ohio) were assessed. These results evidenced that oligo I (SEQ ID NO: 9370) has no detrimental effect upon critical cardiovascular parameters. More particularly, this oligo does not cause hypotension. This finding is of particular importance because other phosphorothioate anti-sense oligonucleotides have been shown in the past to induce hypotension in some model systems. Furthermore, the adenosine Ai receptor plays an important role in sinoatrial conduction VΛthin the heart. Attenuation of the adenosine Ai receptor by anti-sense oligo I (SEQ ID NO: 9370) might be expected to result, therefore, in deleterious extrapulmonary activity in response to the downregulation of the receptor. This is not the case. The anti-sense oligo I (SEQ DD NO: 9370) does not produce any deleterious intrapulmonary effects and renders the administration of the low doses of the present anti-sense oligo free of unexpected, undesirable side effects. This demonstrates that when oligo I (SEQ ID NO: 9370) is administered directly to the lung, it does not reach the heart in significant quantities to cause deleterious effects. This is in contrast to traditional adenosine receptor antagonists like theophylline which do escape the lung and can cause deleterious, even life-threatening effects outside the lung. Example 25: Long Lasting Effect of Oligo I

The Oligo I (SEQ ID NO: 9370) evidenced a long lasting effect as evidenced by the PC₅₀ and Resistance values obtained upon its administration prior to adenosine challenge. The duration of the effect was measured for with respect to the PC₅₀ of adenosine anti-sense oligo I when administered in four equal doses of 5 mg each by means of a nebulizer via an endotracheal tube, as described above. The effect of the agent is significant over days 1 to 8 after administration. When the effect of the anti-sense oligo I (SEQ DD NO: 9370) had disappeared, the animals were administered saline aerosols (controls), and the PC_{50 A enos}i_ne values for all animals were measured again.

739 Saline-treated animals showed base line PC₅₀ adenosine values (n=6). The duration of the effect (with respect to Resistance) was measured for six allergic rabbits which were administered 20 mg of anti-sense oligo I (SEQ DD NO: 9370) as described above, upon airway resistance measured as also described above. The mean calculated duration of effect was 8.3 days for both PC₅₀ adenosine (p<0.05) and resistance (p<0.05). These results show that anti-sense oligo I (SEQ ID NO: 9370) has an extremely long duration of action, which is completely unexpected.

Example 26: Anti-sense Oligo π

Anti-sense oligo II, targeted to a different region of the adenosine Ai receptor mRNA, was found to be highly active against the adenosine A_rmediated effects. The experiment measured the effect of the administration of anti-sense oligo II (SEQ DD NO: 9376) upon compliance and resistance values when 20 mg anti-sense oligo II or saline (control) were administered to two groups of allergic rabbits as described above. Compliance and resistance values were measured following an administration of adenosine or saline as described above in Example 13. The effect of the anti-sense oligo of the invention was different from the control in a statistically significant manner, p<0.05 using paired t-test, compliance; p<0.01 for resistance. The results showed that anti-sense oligo II (SEQ ID NO: 9376), which targets the adenosine Ai receptor, effectively maintains compliance and reduces resistance upon adenosine challenge.

Example 27: Antisense Oligos III and IV

Oligos III (SEQ ID NO: 9377) and IV (SEQ ID NO: 9378) were shown to be in fact specifically targeted to the adenosine A₃ receptor by their effect on reducing inflammation and the number of inflammatory cells present upon separate administration of 20 mg of the anti-sense oligos III (SEQ ID NO: 9377) and IV (SEQ ID NO: 9378) to allergic rabbits as described above. The number of inflammatory cells was determined in their bronchial lavage fluid 3 hours later by counting at least 100 viable cells per lavage. The effect of anti-sense oligos III (SEQ ID NO:

9377) and IV (SEQ ID NO: 9378) upon granulocytes, and upon total cells in bronchial lavage were assessed following exposure to dust mite allergen. The results showed that the anti-sense oligo IV (SEQ ID NO: 9378) and anti-sense oligo III (SEQ ID NO: 9377) are very potent anti-inflammatory agents in the asthmatic lung following exposure to dust mite allergen. As is known in the art, granulocytes, especially eosinophils, are the primary inflammatory cells of asthma, and the administration of anti-sense oligos III (SEQ ID NO: 9377) and IV (SEQ ID NO: 9378) reduced their numbers by 40% and 66%, respectively. Furthermore, anti-sense oligos IV (SEQ ID NO:

9378) and III (SEQ ID NO: 9377) also reduced the total number of cells in the bronchial lavage fluid by 40% and 80%, respectively. This is also an important indicator of anti-inflammatory activity by the present anti-adenosine A₃ agents of the invention. Inflammation is known to underlie bronchial hyperresponsiveness and allergen-induced bronchoconstriction in asthma. Both anti-sense oligonucleotides III (SEQ ID NO: 9377) and IV (SEQ DD NO: 9378), wliich are targeted to the adenosine A₃ receptor, are representative of an important new class of anti- inflammatory agents which may be designed to specifically target the lung receptors of each species.

Example 28: Anti-sense Oligo V The anti-sense oligo V (SEQ ID NO: 9379), targeted to the adenosine A₂ adenosine receptor mRNA was shown to be highly effective at countering adenosine A_2b-mediated effects and at reducing the number of adenosine A_2b receptors present to less than half.

Example 29: Unexpected Superiority of Substituted over Phosphodiester-residue Oligo I-DS (SEQ ID NO:11050)

Oligos I (SEQ ID NO:9370) and I-DS (SEQ ID NO:11050) were separately administered to allergic rabbits as described above, and the rabbits were then challenged with adenosine. The phosphodiester oligo I-DS (SEQ ID NO: 11050) was statistically significantly less effective in countering the effect of adenosine whereas oligo I (SEQ ID NO: 9370) showed high effectiveness, evidencing a PC_{50 A enos}i_ne of 20 mg. Example 30: Anti-sense Oligo VI

For the present work, I designed an additional anti-sense phosphorothioate oligo targeted to the adenosine

Ai receptor (Oligo VI). This anti-sense oligo was designed for therapy on a selected species as described in the above patent application and is generally specific for that species, unless the segment of the adenosine receptor mRNA of other species elected happens to have a similar sequence. The anti-sense oligos were prepared as described below, and tested in vivo in a rabbit model for bronchoconstriction, inflammation and lung allergy, which

740 have breathing difficulties and impeded lung airways, as is the case in ailments such as asthma, as described in the above-identified application. One additional oligo and its effect in a rabbit model was studied and the results of the study are reported and discussed below. The present oligo (anti-sense oligo VI) was selected for this study to complement the data on SEQ ID NO: 9370 (Oligo I), which is anti-sense to the adenosine Ai receptor mRNA provided in the above-identified patent application. This additional oligo is identified as anti-sense Oligo VI, and is targeted to a different region of the adenosine Ai receptor mRNA than Oligo I. The design and synthesis of this anti- sense oligo was performed in accordance with the teaching, particularly Example 1, of the above-identified patent application. The anti-sense Oligo VI is a phosphorothioate designed to target the coding region of the rabbit adenosine Ai receptor mRNA region +964 to +984 relative to the initiation codon (start site). The Oligo VI was prepared as described in the above-indicated application, and is 20 nucleotides long. The Oligo VI is directed to the adenosine A. receptor gene, and has the following sequence: 5'-CGC CGG CGG GTG CGG GCC GG-3' (SEQ ID NO: 12491). The phosphorothioate anti-sense Oligo VI having the sequence described in (5) above, was synthesized on an Applied Biosystems Model 396 Oligonucleotide Synthesizer, and purified using NENSORB chromatography (DuPont, DE). TETD (tetraethylthiuram disulfide) was used as the sulfurizing agent during the synthesis.

Example 31: Preparation of Allergic Rabbits

Neonatal New Zealand white Pasturella-free rabbits were immunized intraperitoneally within 24 hours of birth with 0.5 ml of 312 antigen units/ml house dust mite (D. farinae) extract (Berkeley Biologicals, Berkeley, CA) mixed with 10% kaolin as previously described (Metzger, W. J., in Late Phase Allergic Reactions, Dorsch, W., Ed., CRC Handbook, pp 347-362, CRC Press, Boca Raton, 1990; Ali, S. Et al., Am. J. Resp. Crit. Care Med. 149: 908

(1994)). The immunizations were repeated weekly for the first month and then bi-weekly until the animals were 4 months old. These rabbits preferentially produce allergen-specific IgE antibody, typically respond to aeroallergen challenge with both an early and late-phase asthmatic response, and show bronchial hyper responsiveness (BHR). Monthly intraperitoneal administration of allergen (312 units dust mite allergen, as above) continues to stimulate and maintain allergen-specific IgE antibody and BHR. At 4 months of age, sensitized rabbits were prepared for aerosol administration as described by Ali et al. (1994), supra. Example 32: Adenosine Aerosol Preparation

An adenosine aerosol (20 mg/ml) was prepared with an ultrasonic nebulizer (Model 646, DeVilbiss, Somerset, PA), which produced aerosol droplets, 80% of which were smaller than 5:m in diameter. Equal volumes of the aerosols were administered directly to the lungs via an intratracheal tube to all three rabbits. The animals were then administered the aerosolized adenosine and Day 1 pre-treatment values for sensitivity to adenosine were calculated as the dose of adenosine causing a 50% loss of compliance (PC₅₀ Adenosine). The animals were then administered the aerosolized anti-sense via the intratracheal tube (5 mg/1.0 ml), for 2 minutes, twice daily for 2 days (total dose, 20 mg). Post-treatment PC ₀ values were recorded (post-treatment challenge) on the morning of the third day. The results of these studies are provided in (9) below.

Example 33: Anti-sense Oligo Formulation

Each one of anti-sense oligos were separately solubilized in an aqueous solution and administered as described for anti-sense oligo I in (e) above, in four 5 mg aliquots (20 mg total dose) by means of a nebulizer via endotracheal tube, as described above. Example 34: Oligo VI Reduces Response to Adenosine

Challenge as well or Better than Oligo I

Oligo VI was tested in three allergic rabbits of the characteristics and readied as described in (7) above and in the above-indicated patent application. Oligo VI targets a section of the coding region of the Ai receptor which is different from Oligo I. Both these target sequences were selected randomly from many possible coding region target sequences. The three rabbits were treated identically as previously indicated for Oligo I. Briefly, 5 mg of Oligo VI were nebulized to the rabbits twice per day at 8 hour intervals, for two days. Thereafter, PC₅₀ adenosine studies were performed on the morning of the third day and compared to pre-treatment PC₅₀ values. This protocol is described in more detail in Nyce and Metzger (Nyce & Metzger, Nature 385: 721-725 (1997)). The results obtained for the three rabbits are shown in Table 7 below. Table 7: PC_S0 Adenosine before & after Aerosolized Adenosine Treatment

741 Treatment Time PC₅₀ Adenosine

(ms)

Pre-treatment 3.0 +2.1 Post-treatment >20.0*

* maximum achievable dose due to adenosine insolubility in saline

All three animals treated with Oligo VI, completely eliminated sensitivity to adenosine up to the measurable level of the agent shown in Table 7 above. That is, the administration of the Oligo VI abrogated the adenosine-induced bronchoconstriction in the three allergic rabbits. The actual efficacy of Oligo VI is, therefore, greater than could be measured in the experimental system used. By comparing with the previously submitted results for the Oligo I, it may be seen that the Oligo VI was found to be as effective, or more, than Oligo I.

Example 34: Conclusions

The work described and results discussed in the examples clearly indicates that all anti-sense oligonucleotides designed in accordance with the teachings of the above-identified application were found to be highly effective at countering or reducing effects mediated by the receptors they are targeted to. That is, each and all of the two anti-sense oligos targeting an adenosine Ai receptor mRNA, 1 anti-sense oligo targeting an adenosine A₂ receptor mRNA, and the 2 anti-sense oligos targeting an A₃ receptor mRNA were shown capable of countering the effect of exogenously administered adenosine wliich is mediated by the specific receptor they are targeted to. The activity of the anti-sense oligos of this invention, moreover, is specific to the target and substitutively fails to inhibit another target. In addition, the results presented also show that the administration of the present agents results in extremely low or non-existent deleterious side effects or toxicity. This represents 100% success in providing agents that are highly effective and specific in the treatment of bronchoconstriction and/or inflammation. This invention is broadly applicable in the same manner to all gene(s) and corresponding mRNAs encoding proteins involved in or associated with airway diseases. A comparison of the phosphodiester and a version of the same oligonucleotide wherein the phosphodiester bonds are substituted with phosphorothioate bonds evidenced an unexpected superiority for the phosphothiorate oligonucleotide over the phosphodiester anti-sense oligo.

Example 35: In Vivo Response to Adenosine Challenge with & without Oligo I Pretreatment

Two hyper responsive monkeys (ascaris sensitive) were challenged with inhaled adenosine, with and without pre-treatment with anti-sense oligo I (SEQ DD NO: 9370). The PC₄₀ adenosine was calculated from the data collected as being equivalent to that amount of adenosine in mg that causes a 40% decrease in dynamic compliance in hyper-responsive airways. The Oligo I (SEQ DD NO: 9370; EPI 2010) was subsequently administered at 10 mg/day for 2 days by inhalation. On the third day, the PC adenosine was again measured. The PC₄₀ adenosine value prior to treatment with Oligo I was compared side-by-side with to the PC ₀ adenosine taken after administration of Oligo I (Figure not shown). The results of the experiment conducted with two animals showed that any sensitivity to adenosine was completely eliminated by the administration of the oligo of this invention in one animal, and substantially reduced in the second.

Example 36: Extension of the experimental Results

The method of the present invention is also practiced with anti-sense oligonucleotides targeted to many genes, mRNAs and their corresponding proteins as described above, in essentially the same manner as given above, for the treatment of various conditions in the lungs. Examples of these are Human A_2a adenosine receptor, Human

A_2b adenosine receptor, Human IgE receptor β, Human Fc-epsilon receptor CD23 antigen (IgE receptor), Human IgE receptor, subunit, Human IgE receptor, Fc epsilon R, Human histidine decarboxylase, Human beta tryptase, Human tryptase-I, Human prostaglandin D synthase, Human cyclooxygenase-2, Human eosinophil cationic protein, Human eosinophil derived neurotoxin, Human eosinophil peroxidase, Human intercellular adhesion molecule-1 (ICAM-1), Human vascular cell adhesion molecule 1 (VCAM-1), Human endothelial leukocyte adhesion molecule

(ELAM-1), Human P Selectin, Human endothelial monocyte activating factor, Human IL3, Human IL4, Human IL5, Human IL6, Human monocyte-derived neutrophil chemotactic factor, Human neutrophil elastase (medullasin), Human neutrophil oxidase factor, Human cathepsin G, Human defensin 1, Human defensin 3, Human macrophage inflammatory protein-1 -alpha, Human muscarinic acetylcholine receptor HMl, Human muscarinic acetylcholine receptor HM3, Human fibronectin, Human interleukin 8, Human GM-CSF, Human tumor necrosis factor a, Human

742 leukottiene C4 synthase, Human major basic protein, and many more.

In Examples 36 to 42, micronized anti-sense oligo targeting the adenosine Ai receptor (EPI 2010) and micronized salmeterol (as the hydroxynaphthoate) are added in the proportions given below either dry or after predispersal in a small quantity of stabilizer, disodium dioctylsulphosuccinate, lecithin, oleic acid or sorbitan solvent solution to a suspension vessel containing the main bulk of the solvent. The resulting suspension is further dispersed by an appropriate mixing system using, for example, a high shear blender, ultrasonics or a microfluidiser until an ultrafine dispersion is created. The suspension is then continuously recirculated to suitable filling equipment designed for cold fill or pressure filling of dichlorodifluoromethane. The suspension may be also prepared in a suitable chilled solution of stabilizer, in solvent.

Example 37: Metered Dose Inhaler

Active Ingredient Target per Actuation

Salmeterol 25.0 μg (as hydroxynaphthoate)

EPI 2010 l mg

Stabilizer 5.0 μg

Solvent (1) 23.70 mg

Solvent (2) 61.25 mg

Example 38: Metered Dose Inhaler

Active Ingredient Target per Actuation

Salmeterol 25.0 μg (as hydroxynaphthoate)

EPI 2010 5 mg

Stabilizer 7.5 μg

Solvent (1) 23.67 mg

Solvent (2) 61.25 mg

Example 39: Metered Dose Inhaler

Active Ingredient Target per Actuation

Salmeterol 25.0 μg (as hydroxynaphthoate)

EPI 2010 30 mg

Stabilizer 25.0 μg

Solvent (1) 23.45 mg

Solvent (2) 61.25 mg

Example 40: Metered Dose Inhaler

Active Ingredient Target per Actuation

Albuterol 25.0 μg (as hydroxynaphthoate)

EPI 2010 1.0 mg

Stabilizer 15.0 μg

Solvent (1) 23.56 mg

Solvent (2) 61.25 mg

743 Example 41: Metered Dose Inhaler

Active Ingredient Target per Actuation

Albuterol 25.0 μg

(as hydroxynaphthoate)

EPI 2010 5.0 mg

Stabilizer 15.0 μg

Solvent (1) 23.56 mg

Solvent (2) 61.25 mg

Example 42: Metered Dose Inhaler

Active Ingredient Target per Actuation

Albuterol 100.0 μg

(as hydroxynaphthoate)

EPI 2010 30.0 mg

Stabilizer 25.0 μg

Solvent (1) 23.43 mg

Solvent (2) 61.25 mg

In the following Examples 43 to 48, the active ingredients are micronized and bulk blended with lactose in the proportions given above. The blend is filled into hard gelatin capsules or cartridges or into specifically constructed double foil blister packs (Rotadisks blister packs, Glaxo® to be administered by an inhaler such as the Rotahaler inhaler (Glaxo®) or in the case of the blister packs with the Diskhaler inhaler (Glaxo®).

Example 43: Metered Dose Dry Powder Formulation

Active Ingredient /cartridge or blister

Salmeterol (hydroxynaphthoate) 72.5 μg

EPI 2010 0.05 mg

Lactose Ph. Eur. to 12.5 or 25.0 mg

Example 44: Metered Dose Dry Powder Formulation

Active Ingredient /cartridge or blister

Albuterol (hydroxynaphthoate) 72.5 μg

EPI 2010 0.1 mg

Lactose Ph. Eur. to 12.5 or 25.0 mg

Example 45: Metered Dose Dry Powder Formulation

Active Ingredient /cartridge or blister

Albuterol (hydroxynaphthoate) 72.5 μg

EPI 2010 0.15 mg

Lactose Ph. Eur. to 12.5 or 25.0 mg

Example 46: Metered Dose Dry Powder Formulation

Active Ingredient /cartridge or blister

Salmeterol (hydroxynaphthoate) 72.5 μg

EPI 2010 0.01 mg

Lactose Ph. Eur. to 12.5 or 25.0 mg

Example 47: Metered Dose Dry Powder Formulation

Active Ingredient /cartridge or blister

Salmeterol (hydroxynaphthoate) 72.5 μg

EPI 2010 0.05 mg

Lactose Ph. Eur. to 12.5 or 25.0 mg

744 Example 48: Metered Dose Dry Powder Formulation

Active Ingredient /cartridge or blister

Salmeterol (hydroxynaphthoate) 145.0 μg EPI 2010 0.1 mg Lactose Ph. Eur. to 12.5 or 25.0 mg

The foregoing examples are illustrative of the present invention, and are not to be construed as limiting thereof. The invention is defined by the following claims, with equivalents of the claims to be uicluded therein.

745

Claims

WHAT IS CLAIMED AS NOVEL & UNOBVIOUS IN UNITED STATES LETTERS PATENT IS:

1. A pharmaceutical composition, comprising a pharmaceutically or veterinarily acceptable carrier or diluent, and preventative, prophylactic or therapeutic amounts of first and second active agents; the first active agent comprising an oligonucleotide(s) (oligo(s)) which is (are) effective for alleviating bronchoconstriction and/or respiratory tract inflammation or allergies, for reducing adenosine sensitivity, or levels of adenosine or adenosine receptors, or surfactant depletion or hyposecretion, when administered to a mammal, the oligo containing about 0 to about 15% adenosine (A) and being anti-sense to a target comprising the initiation codon, the coding region, the 5'-end or the 3'-end genomic flanking regions, the 5' or 3' intron-exon junctions, or regions within 2 to 10 nucleotides of the junctions of at least one gene encoding or regulating expression of a target polypeptide associated with lung airway or lung dysfunction or cancer, or is anti-sense to the corresponding mRNA; combinations, multiple target anti-sense oligos, or mixtures thereof; and the second active agent comprising a bronchodilating agent.

2. The composition of claim 1, wherein the oligo of the first active agent is A-free.

3. The composition of claim 1, wherein the target comprises the initiation codon, the coding region, the 5'-end or the 3'-end genomic flanking regions, the 5' or 3' intron-exon junctions, or regions within 2 to 10 nucleotides of the junctions of at least one oncogene(s) and a gene(s) encoding or regulating expression of a target polypeptide(s) associated with lung or airway dysfunction or cancer, or is anti-sense to the corresponding mRNA; combinations, multiple target anti-sense oligos (MTAs) or mixtures thereof; the polypeptides comprising peptide factors or transmitters, antibodies, cytokines, chemokines, enzymes, binding proteins, adhesion molecules, their receptors, or malignancy associated proteins.

4. The composition of claim 3, wherein the target comprises the initiation codon, the coding region, the 5'-end or the 3'-end genomic flanking regions, the 5' or 3' intron-exon junctions, or regions within 2 to 10 nucleotides of the junctions of at least one oncogene(s) or a gene(s) encoding or regulating expression of a target polypeptide(s) associated with lung or airway dysfunction or cancer, or is anti-sense to the corresponding mRNA; combinations, multiple target anti-sense oligos (MTAs) or mixtures thereof; wherein the polypeptides comprise transcription factors, stimulating or activating peptide factors, cytokines, cytokine receptors, chemokines, chemokine receptors, adenosine receptors, bradykinin receptors, endogenously produced specific or non-specific enzymes, immunoglobulins, antibodies, antibody receptors, central nervous system (CNS), peripheral nervous or non-nervous system receptors, CNS or peripheral nervous or non-nervous system peptide transmitters, adhesion molecules, defensins, growth factors, vasoactive peptides or receptors, binding proteins, or malignancy associated proteins.

5. The agent of claim 4, wherein the encoded polyρeptide(s) comprise adenosine receptors Ai, A_2a, A₂ or A₃, bradykinin receptors Bl or B2, NffcB Transcription Factor, Interleukin-8 Receptor (IL-8 R), Interleukin 5 Receptor (IL-5 R), Interleukin 4 Receptor (IL-4 R), Interleukin 3 Receptor (IL-3 R), Interleukin- 1/3 (IL-1/3), Interleukin 1/3 Receptor (IL-1/3 R), Eotaxin, Tryptase, Major Basic Protein, /32-adrenergic Receptor Kinase, Endothelin Receptor A, Endothelin Receptor B, Preproendothelin, Bradykinin B2 Receptor, IgE High Affinity Receptor, Interleukin 1 (IL-1), Interleukin 1 Receptor (IL-1 R), Interleukin 9 (IL-9), Interleukin-9 Receptor (IL-9 R), Interleukin 11 (IL-11), Interleukin-11 Receptor (IL-11 R), Inducible Nitric Oxide Synthase, Cyclo-oxygenase-1 (COX-1), Cyclo-oxygenase-2 (COX-2), Intracellular Adhesion Molecule 1 (ICAM-1) Vascular Cellular Adhesion Molecule (VCAM), Rantes, Endothelial Leukocyte Adliesion Molecule (ELAM-1), Monocyte Activating Factor, Neutrophil Chemotactic Factor, Neutrophil Elastase, Defensin 1, 2 and 3, Muscarinic Acetylcholine Receptors, Platelet Activating Factor, Tumor Necrosis Factor , 5-lipoxygenase, Phosphodiesterase IV, Substance P, Substance P Receptor, Histamine Receptor, Chymase, CCR-1 CC Chemokine Receptor, CCR-2 CC Chemokine Receptor, CCR-3 CC Chemokine Receptor, CCR-4 CC Chemokine Receptor, CCR-5 CC Chemokine Receptor, Prostanoid Receptors, GATA-3 Transcription Factor, Neutrophil Adherence Receptor, MAP Kinase, Interleukin-9 (IL-9), NFAT Transcription Factors, STAT 4, MIP-1/3, MCP-2, MCP-3, MCP-4, Cyclophillins, Phospholipase A2, Basic Fibroblast Growth Factor, Metalloproteinase, CSBP/p38 MAP Kinase, Tryptase Receptor, PDG2, Interleukin-3 (IL- 3), Interleukin- 1/3(IL- 1/3), Cyclosporin A-Binding Protein, FK5-Binding Protein, α4/31 Selectin, Fibronectin, cAβl Selectin, Mad CAM-1, LFA-1 (CDl la/CD18), PECAM-1, LFA-1 Selectin, C3bi, PSGL-1, E-Selectin, P-Selectin, CD-34, L-Selectin, pl50,95, Mac-1 (CDl lb/CD18), Fucosyl transferase, VLA-4, CD-18/CDl la, CDllb/CD18, ICAM2, ICAM3, C5a, CCR3 (Eotaxin Receptor), CCR1, CCR2, CCR4, CCR5, LTB-4, AP-1 Transcription Factor, Protein kinase C, Cysteinyl Leukottiene Receptor, Tachychinnen Receptors (tach R), IκB Kinase 1 & 2, STAT 6, c-

746 mas orNF-Interleukin-6 (NF-IL-6).

6. The composition of claim 4, wherein the encoded polypeptide(s) comprise(s) a H2A histone family member N, Tubulin, beta polypeptide, ELL gene (11-19 lysine-rich leukemia gene);7-dehydrocholesterol reductase, ADP-ribosylation factor-like 7, Karyopherin alpha 2 (RAG cohort 1, importin alpha 1), EST (AI038433), EST (AI122689), EST (AI092623), ESTs (AI095492), ESTs (AI138216), ESTs (AI128305), ESTs (AI125228), ESTs (AI041482), ESTs (AI051839), Homo sapiens mRNA; cDNA DKFZp434A1716, ESTs (AI096522), ESTs (AI122807), ESTs (AI041212), EST (AI125651), Enolase 1, (alpha), EST (AI024215), EST (AI034360), Homo sapiens mRNA; cDNA DKFZp564H0764, Homo sapiens mRNA for KIAA1363 protein, partial eds, Potassium voltage-gated channel, shaker-related subfamily, beta member 2, ER-associated DNAJ; ER-associated Hsp40 co- chaperone; hDj9; ERj3, ESTs, Weakly similar to p38 protein [H.sapiens] (AA906703), CGI-142, ESTs (AA463249), Homo sapiens clone 25058 mRNA sequence ESTs (R49144), Squamous cell carcinoma antigen 1, ESTs (AA425700), Myosin X, ESTs (AA459692), Epithelial protein lost in neoplasm beta, CD44 antigen (homing function and Indian blood group system), Coagulation factor III (thromboplastin, tissue factor), ESTs (AA909635), Adducin 1 (alpha), 5' Nucleotidase (CD73), ESTs, moderately similar to semaphorin C [M.musculus] (AA293300), ESTs (AA27S764), ESTs (AA678160), Calmodulin 2 (phosphorylase kinase, delta), ESTs (R42770), Chloride inttacellular channel 1, High-mobility group (nonhistone chromosomal) protein 17, Ubiquitin carrier protein, Tubulin, alpha 1 (testis specific), Transglutaminase 2 (C polypeptide, protem-glutarnine-gamma- glutamylttansferase), Sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican), Proteasome (prosome, macropain) 26S subunit, non-ATPase, 2, Tubulin, beta polypeptide, Filamin B, beta (actin-binding protein-278), Stanniocalcin, Low density lipoprotein receptor (familial hypercholesterolemia), Plectin 1, intermediate filament binding protein, 500kD, S100 calcium-binding protein A2, Immediate early response 3, Calpain, large polypeptide L2, Pleckstrin homology-like domain, family A, member 1, Melanoma adhesion molecule, CD44 antigen (homing function and Indian blood group system), Programmed cell death 5, Hexokinase 1, Vascular endothelial growth factor, Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), Calumenin, Syntaxin 11, Diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor), Fnl4 for type I ttansmenmbrane protein, Nef-associated factor 1, High-mobility group (nonhistone chromosomal) protein isoforms I and Y, Catechol-O-methylteansferase, C-terminal binding protein 1, Collagen, type XVII, alpha 1, ESTs (N58473), Farnesyl-diphosphate farnesylteansferase 1 RNA helicase-related protein, Interferon stimulated gene (20kD), Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1), Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin), Collagen, type XVII, alpha 1, Keratin 18, Heparan sulfate (glucosamine) 3-O-sulfotransferase 1, Tubulin, alpha 2, Adenylyl cyclase-associated protein, Forkhead box Dl, Cathepsin C, ESTs, Highly similar to AF151802_1 CGI-44 protein [H.sapiens] (T74688), Ribonucleotide reductase M2 polypeptide, Laminin, gamma 2 (nicein (lOOkD), kalinin (105kD), BM600 (lOOkD), Herlitz junctional epidermolysis bullosa)), Homo sapiens mRNA; cDNA DKFZp586P1622 (from clone DKFZp586P1622), ESTs, Weakly similar to /prediction (AA284245), or Lactate dehydrogenase A.

7. The composition of claim 1, wherein one or more As is(are) substituted by a universal base comprising heteroaromatic bases which bind to a thymidine base but have antagonist activity and less than about 0.3 of the adenosine base agonist or antagonist activity at the adenosine Ai, A_2a, A_2b or A₃ receptors.

8. The composition of claim 7, wherein the heteroaromatic bases comprise pyrimidines or purines, which may be substituted by O, halo, NH₂, SH, SO, S0₂, S0₃, COOH, branched or fused primary or secondary amino, alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, alkoxy, alkenoxy, acyl, cycloacyl, arylacyl, alkynoxy, cycloalkoxy, aroyl, arylthio, arylsulfoxyl, halocycloalkyl, alkylcycloalkyl, alkenylcycloalkyl, alkynylcycloalkyl, haloaryl, alkylaryl, alkenylaryl, alkynylaryl, arylalkyl, arylalkenyl, arylalkynyl, arylcycloalkyl, which may be further substituted by O, halo, NH₂, primary, secondary or tertiary amine, SH, SO, S0₂, S0₃, cycloalkyl, heterocycloalkyl or heteroaryl.

9. The composition of claim 8, wherein the purines are substituted at positions 1, 2, 3, 6, and/or 8, the pyrimidines are substituted at positions 2, 3, 4, 5 and/or 6, and the purines and pyrimidines have the chemical formula

747

PURINES or

PYRIMIDINES wherein R¹ and R² are independently H, alkyl, alkenyl or alkynyl and R³ is H, aryl, dicycloalkyl, dicycloalkenyl, dicycloalkynyl, cycloalkyl, cycloalkenyl, cycloalkynyl, O-cycloalkyl, 0-cycloalkenyl, O-cycloalkynyl, NH₂- allcylamino-ketoxyalkyloxy-aryl, or mono or dialkylammoalkyl-N-alkylamino-Sθ₂aryl, and R4 and R5 are independently RI and together are R3, and the pyrimidines and purines optionally comprise theophylline, caffeine, dyphylline, etophylline, acephylline piperazine, bamifylline, enprofylline or xantine.

10. The composition of claim 9, wherein the universal base comprises 3-nitropyrrole-2'- deoxynucleoside, 5-niteo-indole, 2-deoxyribosyl-(5-niteoindole), 2-deoxyribofuranosyl-(5-nittoindole), 2'- deoxyinosine, 2'-deoxynebularine, 6H, 8H-3,4-dihydropyrimido [4,5-c] oxazine-7-one or 2-amino-6- methoxyaminopurine.

11. The composition of claim 1, where one or more methylated cytocine(s) (^mC) is(are) substituted for a C in one or more CpG dinocleotide(s), if present in the oligo(s).

12. The composition of claim 1, wherein one or more mononucleotide(s) of the first active agent(s) is(are) linked or modified by one or more of methylphosphonate, 5'-N-carbamate, phosphottiester, phosphorothioate, phosphorodithioate, boranophosphate, formacetal, thioformacetal, thioetlier, carbonate, carbamate, sulfate, sulfonate, sulfamate, sulfonamide, sulfone, sulfite, sulfoxide, sulfide, hydroxylamine, methylene(methyimino) (MMI), methoxymethyl (MOM), methoxyethyl (MOE), methyleneoxy (methylimino) (MOMI), 2'-0-methyl, phosphoramidate, or C-5 substituted residues.

13. The composition of claim 12, wherein the mononucleotide residues are linked by phosphorothioate residues.

14. The composition of claim 1, wherein the first active agent(s) comprises about 7 to about 60 mononucleotides .

15. The composition of claim 1, wherein the anti-sense oligo comprises fragments 1, 3, 5, 7 and 8 to 2313 (SEQ ID NOS: 1 through 14639).

16. The composition of claim 1, wherein the anti-sense oligo is operatively linked to, or complexed with, an agent selected from the group consisting of cell internalized or up-taken agents and cell targeting agents.

17. The composition of claim 1, wherein the second active agent comprises a βl adrenergic agonist, anti-cholinergic agent, theophylline, anti-Mstaminic agent, adenosine receptor antagonist or glucocorticosteroid.

748

18. The composition of claim 17, wherein the second active agent comprises a βl adrenergic agonist selected from ephedrine, isoproterenol, isoetharine, epinephrine, metaproterenol, terbutaline, fenoterol, procaterol, albuterol, salbutamol, pirbuterol, formoterol, biloterol, bambuterol, salmeterol or seretide.

19. The composition of claim 17, wherein the second active agent comprises a glucocorticosteroid.

20. The composition of claim 17, wherein second active agent comprises an anti-cholinergic agent.

21. The composition of claim 17, wherein the second active agent comprises a theophylline.

22. The composition of claim 1, wherein the oligo is operatively linked to a vector that is a prokaryotic or eukaryotic vector.

23. The composition of claim 1, wherein the carrier or diluent comprises a gaseous, liquid or solid carrier or diluent, and the first active agent(s) is present in an amount of about 0.01 to about 99.99 w/w of the composition.

24. The composition of claim 1, further comprising an agent selected from other therapeutic agents, surfactants, flavoring and coloring agents, fillers, volatile oils, buffering agents, dispersants, RNA inactivating agents, anti-oxidants, flavoring agents, propellants or preservatives.

25. The composition of claim 24, wherein the other therapeutic or bioactive agents are selected from analgesics, pre-menstrual medications, menopausal agents, anti-aging agents, anti-anxyolytic agents, mood disorder agents, anti-depressants, anti-bipolar mood agents, anti-schyzophrenic agents, anti-cancer agents, alkaloids, blood pressure controlling agents, hormones, anti-inflammatory agents, muscle relaxants, steroids, soporific agents, anti- ischemic agents, anti-arrythmic agents, contraceptives, vitamins, minerals, ttanquilizers, neurotransmitter regulating agents, wound healing agents, anti-angyogenic agents, cytokines, growth factors, anti-metastatic agents, antacids, anti-Mstaminic agents, anti-bacterial agents, anti-viral agents, anti-gas agents, appetite suppressants, sun screens, emollients, skin temperature lowering products, radioactive phosphorescent or fluorescent contrast diagnostic or imaging agents, libido altering agents, bile acids, laxatives, anti-diarrheic agents, skin renewal agents, hair growth agents, analgesics, pre-menstrual medications, anti-menopausal agents, hormones, anti-aging agents, anti-anxiolytic agents, nociceptic agents, mood disorder agents, anti-depressants, anti-bipolar mood agents, anti-schizophrenic agents, anti-cancer agents, alkaloids, blood pressure controlling agents, hormones, anti-inflammatory agents, arthritis, burns, wounds, chronic bronchitis, chronic obstructive pulmonary disease (COPD), inflammatory bowel disease such as Crohn's disease, ulcerative colitis, autoimmune disease, lupus erythematosus, muscle relaxants, steroids, soporific agents, anti-ischemic agents, anti-arrhythmic agents, contraceptives, vitamins, minerals, ttanquilizers, neurotransmitter regulating agents, wound and burn healing agents, anti-angiogenic agents, cytokines, growth factors, anti-metastatic agents, antacids, anti-histaminic agents, anti-bacterial agents, anti-viral agents, anti- gas agents, agents for reperfusion injury, counteracting appetite suppressants, sun screens, emollients, skin temperature lowering products, radioactive phosphorescent or fluorescent contrast diagnostic or imaging agents, libido altering agents, bile acids, laxatives, anti-diarrheic agents, skin renewal agents or hair growth agents.

26. The composition of claim 24, wherein the surfactant comprioses surfactant protein A, surfactant protein B, surfactant protein C, surfactant protein D and surfactant Protein E, partially or fully saturated phosphatidylcholine (other than dipalmitoyl), dipalmitoylphosphatidylcholine, phosphatidylcholine, phosphatidylglycerol, phosphatidylinositol, phosphatidylethanolamine, phosphatidylserine; phosphatidic acid, ubiquinones, lysophosphatidylemanolamine, lysophosphatidylcholine, palmitoyl- lysophosphatidyl choline, dehydroepiandrosterone, dolichols, sulfatidic acid, glycerol-3-phosphate, dihydroxyacetone phosphate, glycerol, glycero-3-phosphocholine, dihydroxyacetone, palmitate, cytidine diphosphate (CDP) diacylglycerol, CDP choline, choline, choline phosphate; as well as natural and artificial lamellar bodies which are the natural carrier vehicles for the components of surfactant, omega-3 fatty acids, polyenic acid, polyenoic acid, lecithin, palmitinic acid, non-ionic block copolymers of ethylene or propylene oxides, polyoxypropylene, monomeric and polymeric, polyoxyethylene, monomeric and polymeric, poly (vinyl amine) with dexttan and/or alkanoyl side chains, Brij 35, Triton X-100 and synthetic surfactants ALEC, Exosurf, Survan or Atovaquone.

27. The composition of claim 1, comprising one or more oligo(s), a beta 2 adrenergic agonist, a surfactant, and a carrier or diluent for the oligo, the beta 2 adrenergic agent and the surfactant.

28. The composition of claim 22, wherein the agent is an RNA inactivating agent that comprises an enzyme, optionally a ribozyme.

29. The composition of claim 1, which is a systemic or topical formulation comprising an oral, inteabuccal, intrapulmonary, rectal, intrauterine, inttatunor, inttacranial, nasal, intramuscular, subcutaneous,

749 inttavascular, intrathecal, inhalable, ttansdermal, intradermal, inttacavitary, implantable, iontophoretic, ocular, vaginal, intraarticular, otical, intravenous, intramuscular, inttaglandular, intraorgan, inttalymphatic, implantable, slow release or enteric coating formulation.

30. The formulation of claim 29, which is an oral formulation, wherein the carrier is selected from the group consisting of solid and liquid carriers in the form of a powder, dragee, tablet, capsule, spray, aerosol, solution, suspension or emulsion, optionally oil-in-water or water-in-oil emulsion.

31. The formulation of claim 29, which is a topical formulation, wherein the carrier is selected from the group consisting of creams, gels, ointments, sprays, aerosols, patches, solutions, suspensions and emulsions.

32. The formulation of claim 29, which is an injectable formulation, wherein the carrier is selected from the group consisting of aqueous and alcoholic solutions and suspensions, oily solutions and suspensions and oil-in-water and water-in-oil emulsions.

33. The formulation of claim 29, which is a rectal formulation, optionally a suppository.

34. The formulation of claim 29, which is a ttansdermal formulation, wherein the carrier is selected from the group consisting of aqueous and alcoholic solutions, oily solutions and suspensions and oil-in-water and water-in-oil emulsions.

35. The transdermal formulation of claim 34, which is an iontophoretic transdermal formulation, wherein the carrier is selected from the group consisting of aqueous and alcoholic solutions, oily solutions and suspensions and oil-in-water and water-in-oil emulsions, and wherein the formulation further comprises a ttansdermal transport promoting agent.

36. The formulation of claim 29, which is provided in an implant, a capsule or a cartridge.

37. The composition of claim 21, wherein the carrier comprises a hydrophobic carrier.

38. The formulation of claim 37, wherein the carrier comprises lipid vesicles, optionally liposomes, or particles, optionally microcrystals.

39. The formulation of claim 38, wherein the carrier comprises liposomes, and the liposomes comprise the anti-sense oligo.

40. The formulation of claim 27, wliich is a nasal, inteapulmonary, respirable or inhalable aerosol formulation of particle size about 0.5 to about 10 micron or about 8 to about 100 micron.

41. The composition of claim 1 , in single or multiple unit form.

42. The composition of claim 1 , in bulk.

43. A kit, comprising a delivery device; in a separate container(s), the oligo(s) of claim 1; and instructions for adding a carrier and for use of the kit.

44. The kit of claim 43, wherein the formulation is a respirable formulation and the delivery device comprises a nebulizer which delivers single metered doses of the formulation.

45. The kit of claim 44, wherein the nebulizer comprises an insufflator and the composition is provided in a piercable or openable capsule, cartridge or blister.

46. The kit of claim 45, wherein the delivery device comprises a pressurized inhaler and the composition comprises a suspension, solution or dry formulation of the active agent(s).

47. The kit of claim 46, further comprising, in a separate container, an agent comprising other therapeutic agents, surfactants, anti-oxidants, flavoring agents, fillers, volatile oils, dispersants, antioxidants, propellants, preservatives, buffering agents, RNA inactivating agents, cell-internalized or up-taken agents and coloring agents.

48. The kit of claim 47, comprising, in separate containers, one or more oligos, one or more surfactants, and a carrier or diluent, and optionally other therapeutic agents.

49. The kit of claim 43, wherein the device is a transdermal delivery device, and the kit further comprises a transdermal delivery agent, a ttansdermal carrier or diluent, and instructions for preparing a ttansdermal delivery formulation.

50. The kit of claim 43, wherein the device is an iontophoretic delivery device, and the kit further comprises an iontophoretic agent and instructions for preparing an iontophoretic formulation.

51. A method of preventing or treating a respiratory, lung or malignant disease or condition, comprising simultaneously, sequentially or separately aα'ministering to a subject in need of tteatment the first and second active agents of claim 1 in preventative, prophylactic or therapeutic amounts.

52. The method of claim 51, wherein the first agent is administered as a composition under conditions

750 effective for alleviating bronchoconstriction or lung inflammation or allergies, reducing adenosine or adenosine receptor levels, or adenosine hypersensitivity, or surfactant depletion or hyposecretion.

53. The method of claim 51, wherein the first and second agents iareadministered into the subject's respiratory system.

54. The method of claim 53, wherein the agent(s) is(are) administered by inhalation, respiration, nasally or intrapul onarily.

55. The method of claim 54, wherein the composition is administered directly into the subject's lung (s) or nasally as an aerosol or spray of particle size about 8 to about 100 micron.

56. The method of claim 51, wherein the aάministered composition comprises an amount of the oligo(s) and is administered under conditions effective to reduce the production or availability, or to increase the degradation, of the target mRNA or to reduce the amount of the target polypeptide present in the lungs.

57. The method of claim 33, wherein the agent is administered as a respirable or inhalable aerosol or spray formulation of particle size about 0.5 to about 10 micron..

58. The method of claim 51, wherein the pulmonary obstruction, and/or bronchoconstriction and\or lung inflammation, allergy(ies) and/or surfactant hypoproduction are associated with a disease or condition comprising pulmonary vasoconstriction, inflammation, allergies, asthma, impeded respiration, respiratory distress syndrome (RDS), pain, cystic fibrosis (CF), allergic rhynitis (AR), pulmonary hypertension, emphysema, chronic obstructive pulmonary disease (COPD), pulmonary ttansplantation rejection, pulmonary infections, bronchitis, or cancer.

59. The method of claim 58, wherein the disease or condition is associated with an respiratory tract allergies, and the oligo is anti-sense to a target comprising the initiation codon, the coding region, the 5'-end or the 3'-end genomic flanking regions, the 5' or 3' intron-exon junctions, or regions within 2 to 10 nucleotides of the junctions of at least one gene(s) encoding or regulating expression of an immunoglobulin(s) and antibody(ies) and immunoglobulin and antibody receptors, or are anti-sense to the corresponding mRNA; combinations, MTAs or mixtures thereof.

60. The method of claim 58, wherein the disease or condition is associated with a malignancy or cancer, and the oligo is anti-sense to a target comprising the initiation codon, the coding region, the 5'-end or the 3'- end genomic flanking regions, the 5' or 3' intron-exon junctions, or regions within 2 to 10 nucleotides of the junctions of an oncogene(s) or encodes or regulates expression of a malignancy associated protein, or is(are) anti- sense to the corresponding mRNA; combinations, MTAs or mixtures thereof, and the oligo(s) is(are) administered in an amount effective to reduce either the level of the protein mRNA or of the malignancy associated protein, or to reduce the growth of or provide beneficial characteristics to malignant cells.

61. The method of claim 51 , wherein the composition is administered ttansder ally or systemically.

62. The method of claim 61, wherein the composition is administered orally, inttacavitarily, inttanasally, inttaanally, inttavagmally, inttauterally, inttaarticularly, teansdermally, inttabucally, inttavenously, subcutaneously, intramuscularly, inttavascularly, inteatumorously, inttaglandularly, inttaocularly, inttacranial, into an organ, inttavascularly, inttathecally, intralymphatically, inttaotically, by implantation, by inhalation, inteadermally, intrapulmonarily, inttaotically, by slow release, by sustained release orby a pump. 62. The method of claim 51, wherein the subject is a non-human mammal.

63. The method of claim 51 , wherein the mammal is a human.

64. The method of claim 51, wherein the oligo is administered in amount of about 0.005 to about 150 mg/kg body weight.

65. The method of claim 51 , wherein the oligo is obtained by

(a) selecting fragments of a target nucleic acid having at least 4 contiguous nucleic acids selected from the group consisting of G and C;

(b) obtaining a first oligonucleotide 4 to 60 nucleotides long wliich comprises the selected fragment and has a C and G nucleic acid content of up to and including about 15%; and

(c) obtaining a second oligonucleotide 4 to 60 nucleotides long comprising a sequence which is anti-sense to the selected fragment, the second oligonucleotide having an A base content of up to and including about 15%.

66. The method of claim 65, wherein the first active agent(s) is(are) A-free.

67. The method of claim 52, wherein the target comprises the initiation codon, the coding region, the

5'-end or the 3'-end genomic flanking regions, the 5' or 3' intron-exon junctions, or regions within 2 to 10

751 nucleotides of the junctions of at least one oncogene or a gene encoding or regulating expression of a target polypeptide associated with lung or airway dysfunction or cancer, or is anti-sense to the corresponding mRNA; combinations, MTAs or mixtures thereof; wherein the polypeptide comprises transcription factors, stimulating or activating factors, interleukins, interleukin receptors, chemokines, chemokine receptors, endogenously produced specific or non-specific enzymes, immunoglobulins, antibody receptors, centtal nervous system (CNS) or peripheral nervous or non-nervous system receptors, CNS or peripheral nervous or non-nervous system peptide transmitters, adhesion molecules, defensines, growth factors, vasoactive peptides, peptide receptors and binding proteins, or malignancy associated proteins.

68. The method of claim 52, wherein one or more As in the oligo(s) in the first active agent(s) is(are) substituted by a universal base comprising heteroaromatic bases that bind to thymidine or uridine but have less than about 0.3 of the adenosine base agonist or antagonist activity at an adenosine A A_2a, A_2b or A₃ receptors.

69. The method of claim 68, wherein the heteroaromatic bases comprise pyrimidines or purines, which may be substituted by O, halo, NH₂, SH, SO, S0₂, S0₃, COOH or branched or fused primary or secondary amino, alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, alkoxy, alkenoxy, acyl, cycloacyl, arylacyl, alkynoxy, cycloalkoxy, aroyl, arylthio, arylsulfoxyl, halocycloalkyl, alkylcycloalkyl, alkenylcycloalkyl, alkynylcycloalkyl, haloaryl, alkylaryl, alkenylaryl, alkynylaryl, arylalkyl, arylalkenyl, arylalkynyl, arylcycloalkyl, which may be further substituted by O, halo, NH₂, primary, secondary or tertiary amine, SH, SO, S0₂, S0₃, cycloalkyl, heterocycloalkyl or heteroaryl.

70. The method of claim 68, wherein the the purines are substituted at positions 1, 2, 3, 6, and/or 8, the pyrimidines are substituted at positions 2, 3, 4, 5 and/or 6, and have the chemical formula

PURINES or

PYRIMIDINES wherein R¹ and R² are independently H, alkyl, alkenyl or alkynyl and R³ is H, aryl, dicycloalkyl, dicycloalkenyl, dicycloalkynyl, cycloalkyl, cycloalkenyl, cycloalkynyl, O-cycloalkyl, O-cycloalkenyl, 0-cycloalkynyl, NH₂- alkylamino-ketoxyalkyloxy-aryl, or mono or dialkylammoalkyl-N-alkylamino-S0₂aryl, and R4 and R5 are independently RI and together are R3, and the pyrimidines and purines optionally comprise theophylline, caffeine, dyphylline, etophylline, acephylline piperazine, bamifylline, enprofylline or xantine.

71. The method of claim 70, wherein the universal base comprises 3-nittopyrrole-2'-deoxynucleoside,

5-nitro-indole, 2-deoxyribosyl-(5-niteoindole), 2-deoxyribofuranosyl-(5-nittoindole), 2'-deoxyrnosine, -

752 deoxynebularine, 6H, 8H-3,4-dihydropyrimido [4,5-c] oxazine-7-one or 2-aπr o-6-methoxyaminopurine.

72. The method of claim 53, further comprising substituting a methylated cytocine (^mC) for a C in one or more CpG dinucleotide(s), if present in the oligo(s).

73. The method of claim 53, further comprising substituting by, or modifying one or more nucleotide residue(s) of the oligo(s) with, at least one of methylphosphonate, phosphottiester, phosphorothioate, phosphorodithioate, boranophosphate, formacetal, thioformacetal, thioether, carbonate, carbamate, sulfate, sulfonate, sulfamate, sulfonamide, sulfone, sulfite, sulfoxide, sulfide, hycttoxylamine, methylene(memyimino) (MMI), methoxymethyl (MOM), methoxyethyl (MOE), methyleneoxy (methyli ino) (MOMI), methoxy methyl (MOM), 2'-0-methyl, phosphoramidate, or C-5 substituted residues.

74. The method of claim 52, further comprising operatively linking to, or complexing the oligo(s) with, an agent comprising cell internalized or up-taken agent(s), or cell targeting agents.

75. The method of claim 74, wherein the cell internalized or up taken agent comprises ttansferrin, asialoglycoprotein, and steeptavidin.

76. The method of claim 74, wherein the cell targeting agent comprises a vector selected from a prokaryotic or eukaryotic vector.

77. The method of claim 51, wherein the first and second agents are administered topically to the airway, respiratory or pulmonary epithelium of the subject.

78. The method of claim 77, wherein the first and second agents are administered into the respiratory system as an aerosol or spray of liquid or solid powdered particles about 5 to about 10 μm or about 8 to about 100 μm in size.

753