WO2002094327A2 - Stable pressurized antiperspirant compositions containing dimethylether propellant and a polyol - Google Patents
Stable pressurized antiperspirant compositions containing dimethylether propellant and a polyol Download PDFInfo
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- WO2002094327A2 WO2002094327A2 PCT/US2002/016405 US0216405W WO02094327A2 WO 2002094327 A2 WO2002094327 A2 WO 2002094327A2 US 0216405 W US0216405 W US 0216405W WO 02094327 A2 WO02094327 A2 WO 02094327A2
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- antiperspirant
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- pressurized
- compositions
- low polarity
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/26—Aluminium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
Definitions
- the present invention relates to pressurized antiperspirant compositions comprising solubilized antiperspirant active, a dimethylether propellant, and a low polarity solvent.
- the compositions can be formulated as stable single phase or clear pressurized liquids without reliance upon ethanol, propylene glycol, or aqueous solvents.
- aerosol antiperspirants have been formulated with antiperspirant active dissolved or solubilized in a suitable aqueous or anhydrous carrier.
- Many of these formulations are also single phase systems without any dispersed or suspended solids, thus resulting in little or no visible residue on the applied areas that is attributable to the deposition of such dispersed or suspended solids on the skin.
- These single phase formulations often have a clear or translucent appearance, and apply neatly from an aerosolized spray without a dusty or powdery application.
- Many of these single phase aerosols however, contain ethanol, or water to help solubilize the antiperspirant active to allow for the formulation of a stable, single- phase system.
- Single phase antiperspirant aerosols have also been described in the antiperspirant art in which single phase aerosols are formulated with dimethylether, solubilized antiperspirant active, and polyol solvents such as propylene glycol. These compositions contain dimethylether which allows for the formulation of a stable single-phase system, provided that the system also contains water, ethanol or relatively high propylene glycol concentrations to maintain the stability of the single phase system.
- compositions tend to be unstable when formulated with substantive low polarity solvents, thus resulting in precipitation of antiperspirant active from solution or phase separation shortly after formulation, unless the compositions are modified to contain relatively high ethanol, water or propylene glycol concentrations.
- high ethanol or propylene glycol concentrations can irritate or sting the sensitive underarm area ofthe skin and high water concentrations can result in an undesirably wet skin feel during and after application.
- pressurized antiperspirant products can be formulated as single phase or clear products, without reliance upon high ethanol, propylene glycol, or water concentrations to solubilize and couple antiperspirant active with the various other ingredients to form a single phase or clear system.
- single-phase, pressurized antiperspirants can be prepared without reliance upon such materials provided that it comprises an antiperspirant active solubilized in a polyol solvent having at least 4 carbon atoms and a hydroxyl group on each of the ⁇ and ⁇ carbon atoms of the polyol solvent, wherein the solubilized active and selected polyol solvent are combined with a dimethylether propellant in combination with a low polarity solvent having a solubility parameter of less than about 8.0, wherein the weight ratio ofthe dimethylether to the low polarity solvent is from about 0.1 to about 3.0.
- pressurized single-phase antiperspirant product will remain stable over prolonged periods, provided that the defined polyol solvent and dimethylether propellant are coupled with the low polarity solvent, and provided that the weight ratio of the dimethylether propellant to low polarity solvent is maintained within the range as defined here.
- low polarity solvents or materials can include materials such as volatile or non-volatile silicone fluids that provide additional benefits such as active substantivity, emolliency, improved skin feel during or after application, formulation flexibility, and similar other benefits.
- These low polarity solvents also include liquefied hydrocarbon propellants to provide a low cost option to more expensive propellant materials.
- the present invention is directed to pressurized anhydrous antiperspirant compositions comprising: (a) a polyol solvent having at least 4 carbon atoms and a hydroxyl group on each of the ⁇ and ⁇ carbon atoms of the polyol solvent; (b) solubilized antiperspirant active; (c) dimethylether; (d) a low polarity liquid having a solubility parameter of less than about 8.0, wherein the weight ratio ofthe dimethylether to low polarity solvent is from about 0.1 to about 3.0 It has been found that these compositions are especially useful in formulating clear or single-phase pressurized antiperspirant compositions that remain stable over prolonged periods and that can be formulated without high concentrations of ethanol, propylene glycol or aqueous solvents. It has also been found that these compositions can be maintained as single phase or clear formulations, even when formulated with low polarity solvents such as silicone oils, liquefied hydrocarbon propellants, and other similar materials.
- low polarity solvents
- the pressurized antiperspirant compositions of the present invention comprise a selected polyol solvent, a solubilized antiperspirant active, a dimethylether propellant, and a low polarity solvent in a defined weight ratio relative to the dimethylether propellant.
- anhydrous refers to those compositions or materials containing less than about 5%, more preferably less than about 3%, even more preferably less than about 1%, even more preferably zero percent, by weight of free or added water.
- ambient conditions refers to surrounding conditions at about one atmosphere of pressure, at about 50% relative humidity, and at about 25°C.
- pressurized antiperspirant means any packaged antiperspirant composition that is pressurized from a gas or liquefied gas propellant to thus provide a means for pushing or moving the antiperspirant composition through an application device.
- pressurized antiperspirant compositions of the present invention can comprise, consist of, or consist essentially of the essential elements and limitations of the invention described herein, as well as any additional or optional ingredients, components, or limitations described herein or otherwise useful in pressurized antiperspirant applications.
- the pressurized antiperspirant compositions of the present invention comprise selected liquid polyols for solubilizing or helping to solubilize the antiperspirant active material in the composition.
- the antiperspirant composition preferably comprises from about 1% to about 80%, more preferably from about 2% to about 60%, even more preferably from about 3% to about 20%, by weight ofthe selected liquid polyols.
- liquid polyols for use in the pressurized antiperspirant composition of the present invention are selected to have at least 4 carbon atoms and adjacent hydroxy-substituted carbon atoms at the ⁇ and ⁇ positions of the liquid polyol.
- Preferred liquid polyols for use in the compositions are those that conform to the formula:
- R is an amide, ester, alkyl, ether or silicone-containing moiety, each moiety containing at least 2 carbon atoms.
- the R group is preferably an alkyl or ether group, more preferably an alkyl group having from about 2 to about 10 carbon atoms, more preferably from about 4 to about 6 carbon atoms.
- the liquid polyols preferably have either 2 or 3 hydroxyl groups in total.
- the R group on the liquid polyol can therefore be substituted or unsubstituted, branched or straight or cyclic, saturated or unsaturated.
- suitable substituents include hydroxyl groups, amines, amides, esters, ethers, alkoxylate groups (e.g., ethoxylates, propoxylates, etc.) and so forth.
- Non limiting examples of suitable liquid polyols for use in the pressurized compositions of the present invention include 1,2-butanediol; 1,2-pentanediol; 4-methyl-l,2-pentanediol; 2- methyl- 1,2-pentanediol; 3, 3 -methyl- 1,2-butanediol; 4-methyl-l,2-hexanediol; 1,2-heptanediol; 3- phenyl-l,2-propanediol; 1,2,6-hexanetriol; 1,2-hexandiol; 1 ,2,4-butanetriol; and combinations thereof.
- glycerol ethers such as glycerol isopropyl ether; glycerol propyl ether; glycerol ethyl ether; glycerol methyl ether; glycerol butyl ether; glycerol isopentyl ether; diglycerol isopropyl ether; diglycerol isobutyl ether; diglycerol; triglycerol; triglycerol isopropyl ether; and combinations thereof.
- glycerol ethers such as glycerol isopropyl ether; glycerol propyl ether; glycerol ethyl ether; glycerol methyl ether; glycerol butyl ether; glycerol isopentyl ether; diglycerol isopropyl ether; diglycerol isobutyl ether; diglycerol; triglycerol;
- liquid polyols include acetic acid glycerol ester; propanoic acid glycerol ester; butanoic acid glycerol ester; 3 -methyl butanoic acid glycerol ester; and 3-trimethylsily-l,2-propane diol; silicone-containing 1, 2-diols such as those described in U.S. Patent 5,969,172 (Nye); and combinations thereof.
- polyols are formulated into the antiperspirant composition alone or preferably in combination with one or more other anhydrous liquid earners, examples of such other anhydrous liquid carriers include any known or otherwise effective carrier liquids suitable for topical application to the skin which are also compatible with the solubilized antiperspirant active and propellant components ofthe composition.
- the pressurized antiperspirant compositions of the present invention are preferably anhydrous, but will typically contain at least small amounts of water associated with the antiperspirant active during formulation.
- anhydrous means the antiperspirant compositions of the present invention preferably contain less than 10%, more preferably less than 5%, even more preferably less than 3%, most preferably less than 1%, of water by weight ofthe composition.
- the pressurized antiperspirant compositions ofthe present invention comprise a solubilized antiperspirant active suitable for application to human skin.
- concentration of antiperspirant active in the composition should be sufficient to provide the finished antiperspirant product with the desired perspiration wetness and odor control.
- the antiperspirant active is preferably solubilized by the liquid polyol component described hereinbefore.
- Solubilized antiperspirant active concentrations in the pressurized antiperspirant compositions preferably range from about 0.1% to about 26%, more preferably from about 1% to about 20%), even more preferably from about 2% to about 10%, by weight of the composition. All such weight percentages are calculated on an anhydrous metal salt basis exclusive of water and any complexing or buffering agent such as glycine, glycine salts, or other complexing or buffering agent.
- the solubilized antiperspirant active for use in the antiperspirant compositions of the present invention include any compound, composition or other material having antiperspirant activity.
- Preferred antiperspirant actives include astringent metallic salts, especially the inorganic and organic salts of aluminum, zirconium and zinc, as well as mixtures thereof. Particularly preferred are salts such as aluminum halides, aluminum chlorohydrate, aluminum hydroxyhalides, zirconyl oxyhalides, zirconyl hydroxyhalides, and mixtures thereof.
- Aluminum salts are most preferred for non-contact pressurized compositions.
- Preferred aluminum salts for use in the antiperspirant compositions include those that conform to the formula:
- Al 2 (OH) a Cl b - x H 2 O wherein a is from about 2 to about 5; the sum of a and b is about 6; x is from about 1 to about 6; and wherein a, b, and x may have non-integer values.
- Processes for preparing aluminum salts are disclosed in U.S. Patent 3,887,692, Gilman, issued June 3, 1975; U.S. ' Patent 3,904,741, Jones et al., issued September 9, 1975; U.S. Patent 4,359,456, and Gosling et al., issued November 16, 1982, all of which are incorporated herein by reference. Mixtures of aluminum salts are described in British Patent Specification 1,347,950, Shin et al, published February 27, 1974.
- Zirconium salts for use in the antiperspirant compositions, especially in pressurized contact forms include those which conform to the formula:
- zirconium salts are those complexes which additionally contain aluminum and glycine, commonly known as ZAG complexes.
- ZAG complexes contain aluminum chlorhydroxide and zirconyl hydroxy chloride conforming to the above described formulas. Such ZAG complexes are described in U.S. Patent 3,679,068, Luedders et al., issued February 12, 1974; Great Britain Patent Application 2,144,992, Callaghan et al., published March 20, 1985; and U.S. Patent 4,120,948, Shelton, issued October 17, 1978.
- Preferred antiperspirant actives for use in the compositions include aluminum chlorohydrate, aluminum dichlorohydrate, aluminum sesquichlorohydrate, aluminum chlorohydrex propylene glycol complex, aluminum dichlorohydrex propylene glycol complex, aluminum sesquichlorohydrex propylene glycol complex, aluminum chlorohydrex polyethylene glycol complex, aluminum dichlorohydrex polyethylene glycol complex, aluminum sesquichlorohydrex polyethylene glycol complex, aluminum sulfate buffered, and combinations thereof.
- Non limiting examples of solubilized antiperspirant active for use in the pressurized antiperspirant compositions of the present invention, and methods of making the solubilized active are described in U.S. Patent 6,149,897 (Swaile); U.S. Patent 6,126,928 (Swaile); and U.S. Patent 5,968,489 (Swaile et al), which descriptions are incorporated herein by reference.
- Other non limiting examples of solubilized antiperspirant active and methods of making it are described in EP 0 404 533 (Smith et al.).
- the pressurized antiperspirant compositions of the present invention comprise a dimethylether propellant in combination with a low polarity solvent as defined hereinafter, wherein the weight ratio of the dimethylether to the low polarity solvent ranges from about 0.1 to 2.8, preferably from about 0.2 to about 1.0, more preferably from about 0.2 to about 0.5.
- the propellant component of the pressurized antiperspirant compositions of the present invention may contain only dimethylether or a combination of dimethylether and any other known or otherwise suitable propellant for application to the skin, preferably a combination of dimethylether and a hydrocarbon propellant.
- the dimethylether or total propellant concentration in the pressurized antiperspirant compositions of the present invention ranges from about 5% to about 99%, more typically from about 15% to about 90%, even more preferably from about 30% to about 70%, by weight of the composition.
- the combination of dimethylether and hydrocarbon propellant preferably represents from about 50% to 100%, more preferably 100%, by weight of the total propellant concentration.
- compositions may comprise minor amounts of other propellants such as nitrous oxide, carbon dioxide, and halogenated hydrocarbons such as triclorofluoromethane, diclorodifluoromethane, diclorotetrafluoroethane trichlorotrifluoroethane, trichlorotetrafluoroethane, and monochlorodifluoromethane, and combinations thereof.
- propellants such as nitrous oxide, carbon dioxide, and halogenated hydrocarbons such as triclorofluoromethane, diclorodifluoromethane, diclorotetrafluoroethane trichlorotrifluoroethane, trichlorotetrafluoroethane, and monochlorodifluoromethane, and combinations thereof.
- hydrocarbon propellants suitable for use in the pressurized antiperspirant compositions include any hydrocarbon propellant known for or otherwise suitable for application to human skin, non limiting examples of which include propane, butane, pentane, isobutane, and combinations thereof. These hydrocarbon propellants are generally in the form of liquefied gases when formulated into the antiperspirant compositions, and are characterized for purposes of defining the compositions of the present invention as a low polarity solvent having a solubility parameter less than about 8.0, which low polarity solvents are described in greater detail hereinafter.
- the pressurized antiperspirant compositions of the present invention comprise a low polarity solvent in combination with the above-described dimethylether propellant, wherein the weight ratio ofthe dimethylether and low polarity solvent is selected within the defined range as described hereinbefore.
- the low polarity solvent can be any material that is liquid under ambient conditions or which is otherwise in liquid form within the pressurized composition described herein, and which has a solubility parameter of less than about 8.0, preferably from about 1 to about 6, more preferably from about 1 to about 4.
- the low polarity solvent for use in the composition of the present invention is preferably a liquefied hydrocarbon propellant, non limiting examples of which include propane, butane, isopentane, pentane, isobutane, and combinations thereof.
- the liquefied hydrocarbon propellant acts as both a low polarity solvent and an additional propellant within the pressurized compositions.
- the hydrocarbon propellant as a low polarity solvent is preferably formulated in combination with the dimethylether propellant, wherein the weight ratio of dimethylether to hydrocarbon propellant in this preferred embodiment ranges from about 0.1 to 2.0, more preferably from about 0.1 to 1.0, even more preferably from about 0.2 to about 0.8.
- low polarity solvents suitable for use in the pressurized antiperspirant compositions of the present invention include any silicone or silicone-containing material that is known or otherwise suitable for topical application to the skin, provided that the silicone or silicone- containing material is a liquid under ambient conditions or is otherwise in liquid form within the pressurized antiperspirant compositions of the present invention, and provided that the silicone or silicone-containing material has the requisite solubility parameter as defined herein.
- the silicone or silicone-containing material as a low polarity solvent for use in the pressurized antiperspirant compositions ofthe present invention can be a volatile or non volatile, cyclic or linear or branched chain, substituted or unsubstituted.
- the concentration of the silicone liquid as a low polarity solvent in the composition preferably ranges from about 0.1% to about 50%, more preferably from about 1% to about 25%, more preferably from about 2% to about 15%, by weight of the pressurized antiperspirant composition.
- Non limiting examples of suitable volatile silicones are described in Todd et al., "Volatile Silicone Fluids for Cosmetics", Cosmetics and Toiletries, 91:27-32 (1976), which descriptions are incorporated herein by reference.
- Preferred among these volatile silicones are the cyclic silicones having from about 3 to about 7, more preferably from about 4 to about 5, silicon atoms. Most preferably are those that conform to the formula:
- n is from about 3 to about 7, preferably from about 4 to about 5, most preferably 5.
- These volatile cyclic silicones generally have a viscosity value of less than about 10 centistokes as measured at 25°C.
- Suitable volatile silicones for use herein include, but are not limited to, Cyclomethicone D-5 (commercially available from G. E.
- Non limiting examples of non volatile silicone liquids for use in the pressurized antiperspirant compositions of the present invention include those which conform to either of the formulas:
- n is greater than or equal to 1.
- linear silicone materials will generally have viscosity values of from about 10 centistoke to about 100,000 centistoke, preferably less than about 500 centistoke, more preferably from about 20 centistoke to about 200 centistoke, even more preferably from about 20 centistoke to about 50 centistoke, as measured under ambient conditions.
- Non limiting examples of non-volatile, linear silicones suitable for use in the antiperspirant compositions include but are not limited to, Dow Corning 200, hexamethyldisiloxane, Rhodorsil Oils 70047 available from Rhone-Poulenc, Masil SF Fluid available from Mazer, Dow Coming 225, Dow Corning 1732, Dow Corning 5732, Dow Corning 5750 (available from Dow Corning Corp.); SF-96, SF-1066 and SF18(350) Silicone Fluids (available from G.E.
- silicone liquids as low polarity solvents for use in the pressurized antiperspirant compositions of the present invention include modified or organofunctional silicone carriers such as polyalkylsiloxanes, polyalkyarylsiloxanes, cross-linked silicone elastomers, polyestersiloxanes, polyethersiloxane copolymers, polyfluorosiloxanes, polyaminosiloxanes, and combinations thereof.
- modified silicone carriers are typically liquid under ambient conditions, and have a preferred viscosity of less than about 100,000 centistokes, more preferably less than about 500 centistokes, even more preferably from about 1 centistoke to about 50 centistokes, and most more preferably from about 1 centistoke to about 20 centistokes.
- modified silicone carriers are generally known in the chemical arts, some examples of which are described in 1 Cosmetics, Science and Technology 27-104 (M. Balsam and E. Sagarin ed. 1972); U.S. Patent 4,202,879, issued to Shelton on May 13, 1980; U.S. Patent 5,069,897, issued to Orr on December 3, 1991; which descriptions are incorporated herein by reference.
- the pressurized antiperspirant compositions of the present invention may further comprise many other materials for use as the low polarity solvent, provided that such other materials have the defined solubility parameter and are formulated into the composition such that the weight ratio of the dimethylether to low polarity solvent remains within the ranges described herein.
- Such other materials include volatile and non volatile hydrocarbons in addition to or other than the hydrocarbon propellants described hereinbefore.
- the pressurized antiperspirant compositions of the present invention may further comprise other optional components which may modify the physical, chemical, cosmetic or aesthetic characteristics of the compositions or serve as additional "active" components when deposited on the skin.
- the compositions may also further comprise optional inert ingredients. Many such optional ingredients are known for use in deodorants, antiperspirants or other personal care compositions, and may also be used in the antiperspirant compositions herein, provided that such optional materials are compatible with the essential materials described herein, or do not otherwise unduly impair product performance.
- Non limiting examples of optional ingredients include preservatives, deodorant antimicrobials, fragrances, deodorant perfumes, coloring agents or dyes, thickeners, pH modifiers, surfactants and other wash-off aids, co-solvents, emollients or residue masking liquids other than the silicone liquids described herein, pharmaceutical actives, vitamins, and combinations thereof.
- Preferred optional ingredients include dimethicone copolyols.
- the pressurized antiperspirant compositions may further comprise any organic or silicone-containing liquid carrier other than the selected polyols and silicone liquids described herein, the compositions are preferably substantially free of ethanol, and also preferably substantially free of propylene glycol or dipropylene glycol.
- substantially free means that the pressurized antiperspirant compositions preferably contain less than 5%, more preferably less than 3%, even more preferably less than 1%, most preferably zero percent, by weight of any of these materials individually.
- the pressurized antiperspirant compositions of the present invention are preferably anhydrous formulations, and are also preferably clear or single-single phase liquids, although the present invention is not limited to clear or single-phase systems.
- These pressurized antiperspirant compositions are packaged in any known or otherwise suitable pressurized container for use in delivering the combination of materials described herein for any selected pressurized formulation.
- the pressurized antiperspirant compositions are also preferably free of any suspended or dispersed solids, e.g., insufficient solid concentrations to visibly reduce the clarity of the composition.
- the pressurized antiperspirant composition may be packaged in conventional pressurized containers for use in contact or non-contact product forms.
- Non-contact products from pressurized containers are well known in the antiperspirant and personal care arts, non limiting examples of which are described in U.S. Patents 3,082,917; U.S. Patent 3,083,918; and U.S. Patent 3,544,258, which descriptions are incorporated herein by reference.
- Pressurized contact antiperspirants are likewise known in the antiperspirant art, non limiting examples of which are described in U.S. Patent 5,567,073 (de Laforcade et al.), which description is incorporated herein by reference.
- contact or “contact product form” refers to any known or otherwise suitable pressurized package that comprises an applicator surface to which the antiperspirant composition is delivered under pressure from within the pressurized package, and from which the antiperspirant composition is then applied directly to the underarm area of the skin.
- the applicator surface directly contacts the underarm during application, thus delivering or depositing the antiperspirant composition to the underarm area ofthe skin.
- non-contact or “non-contact product form” as used herein refers to pressurized packages from which the antiperspirant composition is delivered to the underarm through a product stream delivered under pressure from within the package to the skin. In this context, there is no direct contact between any surface of the pressurized package and the underarm.
- the pressurized antiperspirant compositions of the present invention may be prepared by any known or otherwise effective technique, suitable for making and formulating a clear or single phase pressurized antiperspirant formulation.
- These pressurized compositions are generally prepared by adding, individually or as a premix, all ingredients other than the dimethylether and any other selected propellant to a suitable container. The container is then sealed and residual air within the container is evacuated. The propellant is then added as a liquefied gas under appropriate pressures to the sealed container.
- Preferred compositions and methods of manufacture are described hereinafter in the following exemplified embodiments of the pressurized antiperspirant compositions ofthe present invention.
- the dimethylether propellant when used in combination with a hydrocarbon or other similar propellant, is preferably added to the composition after the hydrocarbon or other similar propellant has been added. It has been found that this particular manufacturing sequence helps stabilize the composition during formulation, and thus minimize or eliminate any active precipitation during the manufacturing process.
- This particular manufacturing process is preferably applied to the pressurized antiperspirant compositions of the present invention, but can also be applied to any pressurized antiperspirant composition known or otherwise disclosed in the antiperspirant art that contains a solubilized antiperspirant active and a combination of dimethylether and other propellants such as liquefied hydrocarbon gases.
- compositions described below are formulated by combining and mixing together in a glass bottle (suitable for pressurized packaging) all of the listed ingredients in each composition that are in liquid form under otherwise ambient conditions.
- the glass bottle is then sealed with a delivery valve and evacuated to between 14 and 25 inches of mercury.
- the propellant in each formulation is then added to the glass bottle under appropriate pressure using a burette filler.
- the dimethylether is always added last.
- the resulting packaged composition is then heated in a water bath (150°F) for 5 minutes to assure proper sealing of the valve.
- Each of the resulting compositions is a clear or single-phase pressurized antiperspirant composition that remains stable over prolonged periods of ambient storage without the use of solvents such as ethanol or aqueous solvents.
- compositions described below are formulated with solubilized antiperspirant active solution.
- the solution is prepared by co-spray drying an initial antiperspirant active solution with a moderately polar solvent to form a spray dried active powder, and then dissolving the spray dried active powder in the desired 1,2-diol solvent with simple agitation over a few hours and no added heat, to thus form an antiperspirant active solution for formulation into the pressurized antiperspirant compositions exemplified herein.
- the solubilized antiperspirant active for formulation into the pressurized antiperspirant compositions exemplified herein is prepared by making an aqueous mixture containing 40% by weight of either the aluminum chlorohydrate or aluminum zirconium chlorohydrate glycerin, 9% by weight of butylene glycol, and 2% by weight of polyethylene glycol 1000.
- the resulting aqueous mixture is then spray dried to provide a spray dried powder that contains about 65-75% by weight of anhydrous antiperspirant active and 20% by weight of the moderately polar solvent (solubility parameter ofthe moderately polar solvent being from about 9 to about 15).
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0303858A HUP0303858A2 (en) | 2001-05-23 | 2002-05-23 | Stable pressurized antiperspirant compositions containing dimethylether propellant and a polyol |
MXPA03010673A MXPA03010673A (en) | 2001-05-23 | 2002-05-23 | Stable pressurized antiperspirant compositions containing dimethylether propellant and a polyol. |
CA002445462A CA2445462A1 (en) | 2001-05-23 | 2002-05-23 | Stable pressurized antiperspirant compositions containing dimethylether propellant and a polyol |
JP2002591043A JP2004529964A (en) | 2001-05-23 | 2002-05-23 | Stable pressurized antiperspirant composition containing dimethyl ether propellant and polyol |
EP02729302A EP1390005A2 (en) | 2001-05-23 | 2002-05-23 | Stable pressurized antiperspirant compositions containing dimethylether propellant and a polyol |
AU2002259302A AU2002259302A1 (en) | 2001-05-23 | 2002-05-23 | Stable pressurized antiperspirant compositions containing dimethylether propellant and a polyol |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US09/864,012 | 2001-05-23 | ||
US09/864,012 US6485715B1 (en) | 2001-05-23 | 2001-05-23 | Stable pressurized antiperspirant compositions containing dimethylether propellant and a low polarity solvent |
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WO2002094327A2 true WO2002094327A2 (en) | 2002-11-28 |
WO2002094327A3 WO2002094327A3 (en) | 2003-04-03 |
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PCT/US2002/016405 WO2002094327A2 (en) | 2001-05-23 | 2002-05-23 | Stable pressurized antiperspirant compositions containing dimethylether propellant and a polyol |
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US (1) | US6485715B1 (en) |
EP (1) | EP1390005A2 (en) |
JP (1) | JP2004529964A (en) |
CN (1) | CN1509161A (en) |
AU (1) | AU2002259302A1 (en) |
CA (1) | CA2445462A1 (en) |
HU (1) | HUP0303858A2 (en) |
MX (1) | MXPA03010673A (en) |
WO (1) | WO2002094327A2 (en) |
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US7344707B2 (en) * | 2002-05-15 | 2008-03-18 | The Procter & Gamble Company | Low combustion aerosol products in plastic packages having a reduced fire hazard classification that subsequently reduces storage costs |
US7235229B2 (en) * | 2002-11-22 | 2007-06-26 | The Procter & Gamble Company | Clear, stable, dry-and-non-sticky antiperspirant having a select group of polar silicone emollients |
US8211449B2 (en) * | 2004-06-24 | 2012-07-03 | Dpt Laboratories, Ltd. | Pharmaceutically elegant, topical anhydrous aerosol foam |
DE602006007007D1 (en) * | 2005-07-30 | 2009-07-09 | Unilever Nv | WATER-FREE SPRAY COMPOSITIONS CONTAINING A PARTICULAR ANTITRANSPIRAN AND A HUMIDIFICANT |
WO2019185314A1 (en) * | 2018-03-28 | 2019-10-03 | Unilever Plc | Non-aluminium antiperspirant compositions |
Citations (2)
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WO1996018378A2 (en) * | 1994-12-14 | 1996-06-20 | Fred Presant | Single phase aerosol antiperspirant composition |
WO2001013872A1 (en) * | 1999-08-24 | 2001-03-01 | The Procter & Gamble Company | Compositions containing solubilized, acid-enhanced antiperspirant active |
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EP0404532A1 (en) | 1989-06-23 | 1990-12-27 | The Procter & Gamble Company | Antiperspirant compositions |
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-
2001
- 2001-05-23 US US09/864,012 patent/US6485715B1/en not_active Expired - Fee Related
-
2002
- 2002-05-23 AU AU2002259302A patent/AU2002259302A1/en not_active Abandoned
- 2002-05-23 JP JP2002591043A patent/JP2004529964A/en active Pending
- 2002-05-23 WO PCT/US2002/016405 patent/WO2002094327A2/en not_active Application Discontinuation
- 2002-05-23 CN CNA028101499A patent/CN1509161A/en active Pending
- 2002-05-23 CA CA002445462A patent/CA2445462A1/en not_active Abandoned
- 2002-05-23 MX MXPA03010673A patent/MXPA03010673A/en active IP Right Grant
- 2002-05-23 EP EP02729302A patent/EP1390005A2/en not_active Withdrawn
- 2002-05-23 HU HU0303858A patent/HUP0303858A2/en unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996018378A2 (en) * | 1994-12-14 | 1996-06-20 | Fred Presant | Single phase aerosol antiperspirant composition |
WO2001013872A1 (en) * | 1999-08-24 | 2001-03-01 | The Procter & Gamble Company | Compositions containing solubilized, acid-enhanced antiperspirant active |
Also Published As
Publication number | Publication date |
---|---|
CN1509161A (en) | 2004-06-30 |
HUP0303858A2 (en) | 2004-03-29 |
AU2002259302A1 (en) | 2002-12-03 |
EP1390005A2 (en) | 2004-02-25 |
MXPA03010673A (en) | 2004-03-02 |
JP2004529964A (en) | 2004-09-30 |
WO2002094327A3 (en) | 2003-04-03 |
CA2445462A1 (en) | 2002-11-28 |
US20030007935A1 (en) | 2003-01-09 |
US6485715B1 (en) | 2002-11-26 |
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