WO2002097409A1 - Verfahren zur automatisierten erkennung, spektroskopischen analyse und identifizierung von partikeln - Google Patents
Verfahren zur automatisierten erkennung, spektroskopischen analyse und identifizierung von partikeln Download PDFInfo
- Publication number
- WO2002097409A1 WO2002097409A1 PCT/EP2002/005779 EP0205779W WO02097409A1 WO 2002097409 A1 WO2002097409 A1 WO 2002097409A1 EP 0205779 W EP0205779 W EP 0205779W WO 02097409 A1 WO02097409 A1 WO 02097409A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- particle
- scattered light
- particles
- identification
- analysis
- Prior art date
Links
- 239000002245 particle Substances 0.000 title claims abstract description 59
- 238000000034 method Methods 0.000 title claims abstract description 52
- 238000004611 spectroscopical analysis Methods 0.000 title claims abstract description 8
- 238000001514 detection method Methods 0.000 claims description 10
- 238000011109 contamination Methods 0.000 claims description 8
- 238000004458 analytical method Methods 0.000 claims description 7
- 238000001069 Raman spectroscopy Methods 0.000 claims description 6
- 238000010183 spectrum analysis Methods 0.000 claims description 6
- 230000010354 integration Effects 0.000 claims description 3
- 230000001960 triggered effect Effects 0.000 claims description 2
- 239000000356 contaminant Substances 0.000 abstract description 5
- 239000000523 sample Substances 0.000 description 14
- 238000005259 measurement Methods 0.000 description 7
- 238000001228 spectrum Methods 0.000 description 7
- 229910003460 diamond Inorganic materials 0.000 description 4
- 239000010432 diamond Substances 0.000 description 4
- 230000003287 optical effect Effects 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- 238000006073 displacement reaction Methods 0.000 description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- 238000004364 calculation method Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000011859 microparticle Substances 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000004566 IR spectroscopy Methods 0.000 description 1
- 208000034809 Product contamination Diseases 0.000 description 1
- 238000003841 Raman measurement Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000009795 derivation Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000011896 sensitive detection Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
- G01N15/0205—Investigating particle size or size distribution by optical means, e.g. by light scattering, diffraction, holography or imaging
- G01N15/0211—Investigating a scatter or diffraction pattern
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/88—Investigating the presence of flaws or contamination
- G01N21/94—Investigating contamination, e.g. dust
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
- G01J3/4412—Scattering spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1468—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
- G01N2015/1452—Adjustment of focus; Alignment
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N2021/646—Detecting fluorescent inhomogeneities at a position, e.g. for detecting defects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N2021/653—Coherent methods [CARS]
- G01N2021/656—Raman microprobe
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/88—Investigating the presence of flaws or contamination
- G01N21/8806—Specially adapted optical and illumination features
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/10—Scanning
- G01N2201/103—Scanning by mechanical motion of stage
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/10—Scanning
- G01N2201/108—Miscellaneous
- G01N2201/1087—Focussed scan beam, e.g. laser
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10292357T DE10292357D2 (de) | 2001-05-31 | 2002-05-24 | Verfahren zur automatisierten Erkennung, spektroskopischen Analyse und Identifizierung von Partikeln |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10127538 | 2001-05-31 | ||
DE10127538.2 | 2001-05-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2002097409A1 true WO2002097409A1 (de) | 2002-12-05 |
Family
ID=7687430
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2002/005779 WO2002097409A1 (de) | 2001-05-31 | 2002-05-24 | Verfahren zur automatisierten erkennung, spektroskopischen analyse und identifizierung von partikeln |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE10292357D2 (es) |
WO (1) | WO2002097409A1 (es) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102004008762A1 (de) * | 2004-02-23 | 2005-09-08 | Erwin Kayser-Threde Gmbh | Verfahren und Vorrichtung zur Detektion und zum Identifizieren von Biopartikeln |
WO2008020343A2 (en) * | 2006-08-18 | 2008-02-21 | Primus Special Projects (Pty) Ltd | A sorter |
NL1039263C2 (nl) * | 2011-12-23 | 2013-06-26 | Zevenaar Elektronica & Sensoren B V | Apparaat en werkwijze voor het tellen en bemeten van deeltjes. |
EP1904826B1 (en) * | 2005-07-14 | 2019-02-20 | Battelle Memorial Institute | Systems and methods for biological and chemical detection |
CN110346042A (zh) * | 2019-08-01 | 2019-10-18 | 南京邮电大学 | 一种多传感器杂散光消除光谱仪 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0056426A2 (de) * | 1980-10-08 | 1982-07-28 | Firma Carl Zeiss | Vorrichtung zur Darstellung von Probenparametern |
US4766324A (en) * | 1987-08-07 | 1988-08-23 | Tencor Instruments | Particle detection method including comparison between sequential scans |
DE4111903A1 (de) * | 1991-04-12 | 1992-10-15 | Bayer Ag | Spektroskopiekorrelierte licht-rastermikroskopie |
EP0685731A1 (en) * | 1994-06-02 | 1995-12-06 | Mitsubishi Denki Kabushiki Kaisha | Positioning method and analysis method of fine foreign matter and analyzer used therefor |
DE19946110C1 (de) * | 1999-09-17 | 2001-02-01 | Apsys Advanced Particle System | Optisches Verfahren zur Charakterisierung von Partikeln in einem System, z.B. einem Reinraum, und Vorrichtung zur Durchführung des Verfahrens |
-
2002
- 2002-05-24 DE DE10292357T patent/DE10292357D2/de not_active Ceased
- 2002-05-24 WO PCT/EP2002/005779 patent/WO2002097409A1/de not_active Application Discontinuation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0056426A2 (de) * | 1980-10-08 | 1982-07-28 | Firma Carl Zeiss | Vorrichtung zur Darstellung von Probenparametern |
US4766324A (en) * | 1987-08-07 | 1988-08-23 | Tencor Instruments | Particle detection method including comparison between sequential scans |
DE4111903A1 (de) * | 1991-04-12 | 1992-10-15 | Bayer Ag | Spektroskopiekorrelierte licht-rastermikroskopie |
EP0685731A1 (en) * | 1994-06-02 | 1995-12-06 | Mitsubishi Denki Kabushiki Kaisha | Positioning method and analysis method of fine foreign matter and analyzer used therefor |
DE19946110C1 (de) * | 1999-09-17 | 2001-02-01 | Apsys Advanced Particle System | Optisches Verfahren zur Charakterisierung von Partikeln in einem System, z.B. einem Reinraum, und Vorrichtung zur Durchführung des Verfahrens |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102004008762A1 (de) * | 2004-02-23 | 2005-09-08 | Erwin Kayser-Threde Gmbh | Verfahren und Vorrichtung zur Detektion und zum Identifizieren von Biopartikeln |
DE102004008762B4 (de) * | 2004-02-23 | 2006-10-12 | Erwin Kayser-Threde Gmbh | Verfahren und Vorrichtung zur Detektion und zum Identifizieren von Biopartikeln |
EP1904826B1 (en) * | 2005-07-14 | 2019-02-20 | Battelle Memorial Institute | Systems and methods for biological and chemical detection |
WO2008020343A2 (en) * | 2006-08-18 | 2008-02-21 | Primus Special Projects (Pty) Ltd | A sorter |
WO2008020343A3 (en) * | 2006-08-18 | 2008-04-24 | Primus Special Projects Pty Lt | A sorter |
NL1039263C2 (nl) * | 2011-12-23 | 2013-06-26 | Zevenaar Elektronica & Sensoren B V | Apparaat en werkwijze voor het tellen en bemeten van deeltjes. |
CN110346042A (zh) * | 2019-08-01 | 2019-10-18 | 南京邮电大学 | 一种多传感器杂散光消除光谱仪 |
CN110346042B (zh) * | 2019-08-01 | 2022-03-08 | 南京邮电大学 | 一种多传感器杂散光消除光谱仪 |
Also Published As
Publication number | Publication date |
---|---|
DE10292357D2 (de) | 2004-07-01 |
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