WO2003015870A3 - Radioactive implantable devices and their production methods - Google Patents

Radioactive implantable devices and their production methods Download PDF

Info

Publication number
WO2003015870A3
WO2003015870A3 PCT/US2002/025709 US0225709W WO03015870A3 WO 2003015870 A3 WO2003015870 A3 WO 2003015870A3 US 0225709 W US0225709 W US 0225709W WO 03015870 A3 WO03015870 A3 WO 03015870A3
Authority
WO
WIPO (PCT)
Prior art keywords
base
layer
production methods
implantable devices
layer including
Prior art date
Application number
PCT/US2002/025709
Other languages
French (fr)
Other versions
WO2003015870A2 (en
Inventor
Ludger Dinkelborg
Klaus Urich
Bruce F Monzyk
Stephen C Schmitt
Chad M Cucksey
Derek Campbell
Original Assignee
Schering Ag
Ludger Dinkelborg
Klaus Urich
Bruce F Monzyk
Stephen C Schmitt
Chad M Cucksey
Derek Campbell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag, Ludger Dinkelborg, Klaus Urich, Bruce F Monzyk, Stephen C Schmitt, Chad M Cucksey, Derek Campbell filed Critical Schering Ag
Priority to AU2002323130A priority Critical patent/AU2002323130A1/en
Priority to EP02757092A priority patent/EP1425067A2/en
Priority to JP2003520823A priority patent/JP2004538109A/en
Priority to US10/523,766 priority patent/US20050225156A1/en
Publication of WO2003015870A2 publication Critical patent/WO2003015870A2/en
Publication of WO2003015870A3 publication Critical patent/WO2003015870A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1002—Intraluminal radiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0095—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof radioactive

Abstract

A radiolabeled implantable device includes a base, a first layer including Cu and a radioactive isotope on the base, and a second layer including Sn on the first layer. Preferably, the base is formed of stainless steel and the radioactive isotope is a radioisotope of Re, such as ?188Re or 186¿Re. Alternately, radioisotopes of the following elements may be used: Be, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ga, Ge, As, Y, Zr, Nb, Mo, Tc, Ru, Rh, Pd, Ag, Cd, In, Sn, Sb, Te, Hf, Ta, W, Os, Ir, Pt, Au, Hg, TI, Pb, Bi, Po, At, Th, Pa, U, Np, Pu, Am, Cm, Bk, Cf, Es, Fm, Md, No, Lr. In addition, a process for producing a radiolabeled implantable device includes depositing a first layer including Cu and a radioactive isotope on a base, and depositing a second layer including Sn on the first layer. The process may further include removing Cr¿2?O3 from the base and/or rinsing the base prior to depositing the first layer thereon.
PCT/US2002/025709 2001-08-13 2002-08-13 Radioactive implantable devices and their production methods WO2003015870A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2002323130A AU2002323130A1 (en) 2001-08-13 2002-08-13 Radioactive implantable devices and their production methods
EP02757092A EP1425067A2 (en) 2001-08-13 2002-08-13 Radioactive implantable devices and methods and apparatuses for their production and use
JP2003520823A JP2004538109A (en) 2001-08-13 2002-08-13 Radioimplantable devices and methods and devices for making and using the same
US10/523,766 US20050225156A1 (en) 2002-08-13 2002-08-13 Tension adjustable membrane or mesh seat assembly

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31202901P 2001-08-13 2001-08-13
US60/312,029 2001-08-13

Publications (2)

Publication Number Publication Date
WO2003015870A2 WO2003015870A2 (en) 2003-02-27
WO2003015870A3 true WO2003015870A3 (en) 2003-05-22

Family

ID=23209562

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/025709 WO2003015870A2 (en) 2001-08-13 2002-08-13 Radioactive implantable devices and their production methods

Country Status (5)

Country Link
US (1) US6855103B2 (en)
EP (1) EP1425067A2 (en)
JP (1) JP2004538109A (en)
AU (1) AU2002323130A1 (en)
WO (1) WO2003015870A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005524488A (en) * 2002-05-08 2005-08-18 アボット・ラボラトリーズ Endoprosthesis with extended foot
US7625401B2 (en) * 2003-05-06 2009-12-01 Abbott Laboratories Endoprosthesis having foot extensions
US7625398B2 (en) * 2003-05-06 2009-12-01 Abbott Laboratories Endoprosthesis having foot extensions
US20050064168A1 (en) * 2003-09-22 2005-03-24 Dvorsky James E. Electric field spraying of surgically implantable components
US7166941B2 (en) * 2004-11-18 2007-01-23 General Electric Company Electroplated stator bar end and fitting
WO2007005800A1 (en) * 2005-06-30 2007-01-11 Abbott Laboratories Endoprosthesis having foot extensions
US20070092591A1 (en) * 2005-10-24 2007-04-26 Cyberonics, Inc. Vacuum mandrel for use in fabricating an implantable electrode
US7686756B2 (en) * 2006-08-29 2010-03-30 Ciratech Oncology Brachytherapy devices and related methods and computer program products
CN105821456B (en) * 2016-05-31 2018-03-30 克拉玛依双信防腐技术有限公司 Tube inner wall anode device in electroplating
EP3554626A4 (en) * 2016-12-15 2020-06-03 Luseed Vascular Ltd. Methods and devices for treating vascular related disorders

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998048851A2 (en) * 1997-04-30 1998-11-05 Schering Aktiengesellschaft Stents with a radioactive surface coating
US6059714A (en) * 1999-03-26 2000-05-09 Implant Sciences Corporation Radioactive medical devices
WO2000029501A1 (en) * 1998-11-18 2000-05-25 Emory University Radioactive coating solutions, methods, and substrates
US6077413A (en) * 1998-02-06 2000-06-20 The Cleveland Clinic Foundation Method of making a radioactive stent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6394945B1 (en) * 1997-12-22 2002-05-28 Mds (Canada), Inc. Radioactively coated devices
US6749553B2 (en) * 2000-05-18 2004-06-15 Theragenics Corporation Radiation delivery devices and methods for their manufacture
US6503640B2 (en) * 2000-05-19 2003-01-07 Corus Aluminium Walzeprodukte Gmbh Method of manufacturing an assembly of brazed dissimilar metal components

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998048851A2 (en) * 1997-04-30 1998-11-05 Schering Aktiengesellschaft Stents with a radioactive surface coating
US6077413A (en) * 1998-02-06 2000-06-20 The Cleveland Clinic Foundation Method of making a radioactive stent
WO2000029501A1 (en) * 1998-11-18 2000-05-25 Emory University Radioactive coating solutions, methods, and substrates
US6059714A (en) * 1999-03-26 2000-05-09 Implant Sciences Corporation Radioactive medical devices

Also Published As

Publication number Publication date
WO2003015870A2 (en) 2003-02-27
AU2002323130A1 (en) 2003-03-03
US6855103B2 (en) 2005-02-15
EP1425067A2 (en) 2004-06-09
JP2004538109A (en) 2004-12-24
US20030065242A1 (en) 2003-04-03

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