WO2003020203A3 - Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointments - Google Patents

Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointments Download PDF

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Publication number
WO2003020203A3
WO2003020203A3 PCT/US2002/023954 US0223954W WO03020203A3 WO 2003020203 A3 WO2003020203 A3 WO 2003020203A3 US 0223954 W US0223954 W US 0223954W WO 03020203 A3 WO03020203 A3 WO 03020203A3
Authority
WO
WIPO (PCT)
Prior art keywords
castor oil
lipid
hydrogenated castor
pharmaceutically elegant
oil dispersed
Prior art date
Application number
PCT/US2002/023954
Other languages
French (fr)
Other versions
WO2003020203A2 (en
Inventor
David P Jones
David W Hobson
Pilar P Duque
Original Assignee
Healthpoint Ltd
David P Jones
David W Hobson
Pilar P Duque
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE60229855T priority Critical patent/DE60229855D1/en
Priority to MXPA04001969A priority patent/MXPA04001969A/en
Priority to JP2003524517A priority patent/JP4115391B2/en
Priority to BRPI0212286-3A priority patent/BR0212286A/en
Priority to DK02768363T priority patent/DK1423154T3/en
Priority to CA002459239A priority patent/CA2459239C/en
Application filed by Healthpoint Ltd, David P Jones, David W Hobson, Pilar P Duque filed Critical Healthpoint Ltd
Priority to AU2002330929A priority patent/AU2002330929B2/en
Priority to EP02768363A priority patent/EP1423154B1/en
Priority to KR1020047003208A priority patent/KR100638417B1/en
Publication of WO2003020203A2 publication Critical patent/WO2003020203A2/en
Publication of WO2003020203A3 publication Critical patent/WO2003020203A3/en
Priority to HK04108999.0A priority patent/HK1065963A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Abstract

A topical ointment pharmaceutical composition that uses a lipophilic base, a pharmaceutical active and, dispersed in the base, from about 1 % to about 50 % by weight of the total composition of hydrogenated non-melted castor oil in powder form. The result of using hydrogenated non-melted castor oil in powder form is a surprising pharmaceutical elegance perceived to be smoother in texture and more spreadable than an ointment made by melting the hydrogenated castor oil.
PCT/US2002/023954 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointments WO2003020203A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
MXPA04001969A MXPA04001969A (en) 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointments.
JP2003524517A JP4115391B2 (en) 2001-09-04 2002-07-29 Hardened castor oil dispersed in lipids for use in pharmaceutically elegant topical ointments
BRPI0212286-3A BR0212286A (en) 2001-09-04 2002-07-29 hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointments
DK02768363T DK1423154T3 (en) 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointments
CA002459239A CA2459239C (en) 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointment
DE60229855T DE60229855D1 (en) 2001-09-04 2002-07-29 HYDROGENICIZED CINEMA OIL DISPERSES IN A LIPID FOR PHARMACEUTICALLY ELEGANT TOPICAL OINTMENTS
AU2002330929A AU2002330929B2 (en) 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointments
EP02768363A EP1423154B1 (en) 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointments
KR1020047003208A KR100638417B1 (en) 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointments
HK04108999.0A HK1065963A1 (en) 2001-09-04 2004-11-15 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointments

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/945,903 2001-09-04
US09/945,903 US6479060B1 (en) 2001-09-04 2001-09-04 Elegant hydrogenated castor oil ointments

Publications (2)

Publication Number Publication Date
WO2003020203A2 WO2003020203A2 (en) 2003-03-13
WO2003020203A3 true WO2003020203A3 (en) 2003-07-10

Family

ID=25483673

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/023954 WO2003020203A2 (en) 2001-09-04 2002-07-29 Hydrogenated castor oil dispersed in a lipid for pharmaceutically elegant topical ointments

Country Status (16)

Country Link
US (1) US6479060B1 (en)
EP (1) EP1423154B1 (en)
JP (1) JP4115391B2 (en)
KR (2) KR100764278B1 (en)
CN (1) CN100463697C (en)
AT (1) ATE413861T1 (en)
AU (1) AU2002330929B2 (en)
BR (1) BR0212286A (en)
CA (1) CA2459239C (en)
DE (1) DE60229855D1 (en)
DK (1) DK1423154T3 (en)
ES (1) ES2315400T3 (en)
HK (1) HK1065963A1 (en)
MX (1) MXPA04001969A (en)
PT (1) PT1423154E (en)
WO (1) WO2003020203A2 (en)

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US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
EP1556009B2 (en) 2002-10-25 2021-07-21 Foamix Pharmaceuticals Ltd. Cosmetic and pharmaceutical foam
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US7785584B2 (en) * 2003-08-13 2010-08-31 Healthpoint, Ltd. Ointment wound spray
US20050048105A1 (en) * 2003-08-29 2005-03-03 Mcnulty Amy K. Protease inhibitor compositions for prevention and treatment of skin conditions
US20050100621A1 (en) * 2003-11-07 2005-05-12 Popp Karl F. Dermatological compositions
US20060264505A1 (en) * 2003-11-07 2006-11-23 Stiefel Laboratories, Inc. Dermatological compositions
US20050281806A1 (en) * 2004-06-16 2005-12-22 Collegium Pharmaceutical, Inc., Delaware Compositions for topical enzymatic debridement
US8211449B2 (en) * 2004-06-24 2012-07-03 Dpt Laboratories, Ltd. Pharmaceutically elegant, topical anhydrous aerosol foam
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
AR065378A1 (en) * 2007-02-16 2009-06-03 Procter & Gamble ABSORBENT ARTICLE WITH LOTION THAT INCLUDES A POLYPROPYLENE GLYCOL MATERIAL
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
WO2009072007A2 (en) 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
CA2760186C (en) 2009-04-28 2019-10-29 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
WO2011013008A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
KR101102857B1 (en) * 2009-08-07 2012-01-10 남연우 Kitchen container
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
US8871184B2 (en) 2009-10-02 2014-10-28 Foamix Ltd. Topical tetracycline compositions
AU2010328269B2 (en) 2009-12-08 2014-07-10 Smith & Nephew Orthopaedics Ag Enzymatic wound debriding compositions with enhanced enzymatic activity
CA2776482C (en) * 2010-05-04 2022-06-07 Foamix Ltd. Compositions, gels and foams with rheology modulators and uses thereof
US9011931B1 (en) 2011-01-26 2015-04-21 Libby Robinson Wound dressing composition and method of use
WO2012112566A1 (en) * 2011-02-15 2012-08-23 Allergan, Inc. Pharmaceutical cream compositions of oxymetazoline for treating symptoms of rosacea
AU2012253379A1 (en) 2011-05-12 2013-11-21 Healthpoint, Ltd. Wound debridement compositions containing seaprose and methods of wound treatment using same
NZ701623A (en) 2012-05-11 2016-12-23 Smith & Nephew Inc Use of protease to remove bacterial biofilm
JP7127013B2 (en) 2016-07-27 2022-08-29 スミス アンド ネフュー インコーポレイテッド Use of Thermolysin to Reduce or Remove Bacterial Biofilms from Surfaces
MX2020012139A (en) 2016-09-08 2021-01-29 Vyne Pharmaceuticals Inc Compositions and methods for treating rosacea and acne.
EP3573622B1 (en) 2017-01-30 2023-10-18 Smith & Nephew, Inc. Synergistic combination of thermolysin and an antibacterial agent to reduce or eliminate bacterial biofilms from surfaces
US20220395450A1 (en) * 2021-06-10 2022-12-15 Pauleine Prospere Hair Or Skin Treatment Composition And Methods Of Preparation And Use

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Also Published As

Publication number Publication date
WO2003020203A2 (en) 2003-03-13
DE60229855D1 (en) 2008-12-24
KR20040041597A (en) 2004-05-17
JP2005527468A (en) 2005-09-15
EP1423154A4 (en) 2007-08-15
EP1423154A2 (en) 2004-06-02
ES2315400T3 (en) 2009-04-01
HK1065963A1 (en) 2005-03-11
KR100764278B1 (en) 2007-10-05
MXPA04001969A (en) 2004-07-08
DK1423154T3 (en) 2009-01-26
CN1610563A (en) 2005-04-27
AU2002330929B2 (en) 2005-06-16
CA2459239A1 (en) 2003-03-13
CN100463697C (en) 2009-02-25
JP4115391B2 (en) 2008-07-09
ATE413861T1 (en) 2008-11-15
BR0212286A (en) 2006-05-23
US6479060B1 (en) 2002-11-12
CA2459239C (en) 2005-06-14
KR100638417B1 (en) 2006-10-24
PT1423154E (en) 2009-01-30
KR20060086460A (en) 2006-07-31
EP1423154B1 (en) 2008-11-12

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