WO2003022332B1 - Adaptors for inhalers to improve performance - Google Patents

Adaptors for inhalers to improve performance

Info

Publication number
WO2003022332B1
WO2003022332B1 PCT/US2002/030308 US0230308W WO03022332B1 WO 2003022332 B1 WO2003022332 B1 WO 2003022332B1 US 0230308 W US0230308 W US 0230308W WO 03022332 B1 WO03022332 B1 WO 03022332B1
Authority
WO
WIPO (PCT)
Prior art keywords
adaptor
inhaler
mouthpiece
flow sensor
attachment means
Prior art date
Application number
PCT/US2002/030308
Other languages
French (fr)
Other versions
WO2003022332A3 (en
WO2003022332A2 (en
Inventor
Andrew L Abrams
Anand V Gumaste
Original Assignee
Microdose Technologies Inc
Andrew L Abrams
Anand V Gumaste
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microdose Technologies Inc, Andrew L Abrams, Anand V Gumaste filed Critical Microdose Technologies Inc
Priority to EP02761817A priority Critical patent/EP1446172B1/en
Priority to NZ531614A priority patent/NZ531614A/en
Priority to DE60236011T priority patent/DE60236011D1/en
Priority to AT02761817T priority patent/ATE464083T1/en
Priority to KR10-2004-7003223A priority patent/KR20040039327A/en
Priority to DK02761817.2T priority patent/DK1446172T3/en
Priority to AU2002327052A priority patent/AU2002327052B2/en
Priority to JP2003526459A priority patent/JP4846976B2/en
Priority to MXPA04001859A priority patent/MXPA04001859A/en
Priority to IL16062802A priority patent/IL160628A0/en
Priority to CA2459867A priority patent/CA2459867C/en
Publication of WO2003022332A2 publication Critical patent/WO2003022332A2/en
Publication of WO2003022332A3 publication Critical patent/WO2003022332A3/en
Publication of WO2003022332B1 publication Critical patent/WO2003022332B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A61M16/101—Preparation of respiratory gases or vapours with O2 features or with parameter measurement using an oxygen concentrator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0039—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/18—General characteristics of the apparatus with alarm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3334—Measuring or controlling the flow rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/43—General characteristics of the apparatus making noise when used correctly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A61M2205/584—Means for facilitating use, e.g. by people with impaired vision by visual feedback having a color code

Abstract

A child-sized adaptor (1) for a DPI or MDI is provided. Also provided is a patient feedback mechanism (18) for signaling and/or teaching proper inhaler use.

Claims

AMENDED CLAIMS
[received by the International Bureau on 22 April 2003 (22.04.03)]
What is claimed is: 1. A mouthpiece adaptor for an inhaler comprising: a connecting side for direct connection to a mouthpiece of an inhaler; a mouthpiece side of reduced size relative to the inhaler mouthpiece; and a transition section between said connecting side and mouthpiece side.
2. The adaptor of claim 1 , further comprising attachment means for fixing the mouthpiece adaptor to the mouthpiece of an inhaler.
3. The adaptor of claim 2, wherein said attachment means is a clamp.
4. The adaptor of claim 1 , wherein said inhaler is a dry powder inhaler.
5. The adaptor of claim 1 , wherein said inhaler is a metered dose inhaler.
6. The adaptor of claim 2, wherein the attachment means employs a friction fit.
7. The adaptor of claim 1, wherein the connecting section is funnel shaped.
8. The adaptor of claim 3, wherein the mouthpiece side is round in cross- section.
9. The adaptor of claim 3, wherein the connecting section is covered, at least in part, by a foil.
10. The adaptor of claim 2, wherein said attachment means is a rubber band.
11. The adaptor of claim 1 , wherein the transition section is curved.
12. The adaptor of claim 11 , wherein said transition section is airfoil shaped, in part.
13. The adaptor of claim 1 , wherein said adaptor includes a flow sensor.
14. The adaptor of claim 13, further comprising a noise generator operatively connected to said flow sensor.
15. The adaptor of claim 13, further comprising one or more lights operatively connected to said flow sensor.
16. An inhaler for delivering medication to the respiratory tract comprising a flow sensor for sensing the rate of inhalation and a feedback mechanism to transmit this information to the patient.
17. The patient feedback mechanism according to claim 16 is acoustic, visual in nature.
11
PCT/US2002/030308 2001-09-06 2002-09-06 Adaptors for inhalers to improve performance WO2003022332A2 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
EP02761817A EP1446172B1 (en) 2001-09-06 2002-09-06 Inhalation device type DPI
NZ531614A NZ531614A (en) 2001-09-06 2002-09-06 Adaptors for inhalers to improve performance
DE60236011T DE60236011D1 (en) 2001-09-06 2002-09-06 Inhaler type DPI
AT02761817T ATE464083T1 (en) 2001-09-06 2002-09-06 INHALER TYPE DPI
KR10-2004-7003223A KR20040039327A (en) 2001-09-06 2002-09-06 Adaptors for inhalers to improve performance
DK02761817.2T DK1446172T3 (en) 2001-09-06 2002-09-06 Adapters for inhalers and which serve to improve the latter's performance
AU2002327052A AU2002327052B2 (en) 2001-09-06 2002-09-06 Adaptors for inhalers to improve performance
JP2003526459A JP4846976B2 (en) 2001-09-06 2002-09-06 Adapter to improve the function of the inhaler
MXPA04001859A MXPA04001859A (en) 2001-09-06 2002-09-06 Adaptors for inhalers to improve performance.
IL16062802A IL160628A0 (en) 2001-09-06 2002-09-06 Adaptors for inhalers to improve performance
CA2459867A CA2459867C (en) 2001-09-06 2002-09-06 Adaptors for inhalers to improve performance

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31770601P 2001-09-06 2001-09-06
US60/317,706 2001-09-06

Publications (3)

Publication Number Publication Date
WO2003022332A2 WO2003022332A2 (en) 2003-03-20
WO2003022332A3 WO2003022332A3 (en) 2004-06-03
WO2003022332B1 true WO2003022332B1 (en) 2004-07-15

Family

ID=23234910

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/030308 WO2003022332A2 (en) 2001-09-06 2002-09-06 Adaptors for inhalers to improve performance

Country Status (18)

Country Link
US (2) US7343914B2 (en)
EP (1) EP1446172B1 (en)
JP (1) JP4846976B2 (en)
KR (2) KR100998394B1 (en)
CN (2) CN101239212A (en)
AT (1) ATE464083T1 (en)
AU (1) AU2002327052B2 (en)
CA (1) CA2459867C (en)
CY (1) CY1110147T1 (en)
DE (1) DE60236011D1 (en)
DK (1) DK1446172T3 (en)
ES (1) ES2343239T3 (en)
IL (1) IL160628A0 (en)
MX (1) MXPA04001859A (en)
NZ (1) NZ531614A (en)
PL (1) PL203183B1 (en)
PT (1) PT1446172E (en)
WO (1) WO2003022332A2 (en)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7377277B2 (en) * 2003-10-27 2008-05-27 Oriel Therapeutics, Inc. Blister packages with frames and associated methods of fabricating dry powder drug containment systems
WO2005041848A2 (en) * 2003-10-27 2005-05-12 Oriel Therapeutics, Inc. Dry powder drug containment system packages with tabs, inhalers and associated methods
CN100589849C (en) * 2004-02-24 2010-02-17 微计量技术有限公司 Synthetic jet based medicament delivery method and apparatus
DE102004012093A1 (en) * 2004-03-05 2005-09-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder inhaler with Merkanaldüse
US8231573B2 (en) 2005-02-01 2012-07-31 Intelliject, Inc. Medicament delivery device having an electronic circuit system
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
US8226610B2 (en) 2005-02-01 2012-07-24 Intelliject, Inc. Medical injector with compliance tracking and monitoring
US8361026B2 (en) 2005-02-01 2013-01-29 Intelliject, Inc. Apparatus and methods for self-administration of vaccines and other medicaments
US8206360B2 (en) 2005-02-01 2012-06-26 Intelliject, Inc. Devices, systems and methods for medicament delivery
CN101111281B (en) * 2005-02-01 2013-02-06 因特利杰克特有限公司 Devices, systems, and methods for medicament delivery
DE102005010965B3 (en) * 2005-03-10 2006-08-03 Medspray Xmems Bv Medical inhaler for personal use, comprises a mixing channel with an outlet with a medicament injection area that is designed to be flush with the surface of the channel to less than a millimeter (mm) and ideally less than a tenth of a mm
EP1866016A4 (en) * 2005-03-30 2011-02-16 Canon Kk Liquid medicine ejection device
RU2008110543A (en) * 2005-08-22 2009-09-27 Меди-Стрим Пи Ти Вай Лтд (Au) DEVICE FOR INHALATION OF MEDICINES
EP2357015A3 (en) 2006-04-05 2012-07-25 MicroDose Therapeutx, Inc. Variable dose inhalation device
US20080087279A1 (en) * 2006-10-11 2008-04-17 Tieck Catharine Laureen Johnso Metered dose inhaler
US9179691B2 (en) 2007-12-14 2015-11-10 Aerodesigns, Inc. Delivering aerosolizable food products
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
USD994111S1 (en) 2008-05-12 2023-08-01 Kaleo, Inc. Medicament delivery device cover
US8021344B2 (en) 2008-07-28 2011-09-20 Intelliject, Inc. Medicament delivery device configured to produce an audible output
JP5746625B2 (en) * 2008-08-25 2015-07-08 コーニンクレッカ フィリップス エヌ ヴェ Respiratory drug delivery device providing voice instructions
DE102008054431B3 (en) * 2008-12-09 2010-06-17 Pari Pharma Gmbh Aerosol therapy device
GB2468108A (en) * 2009-02-18 2010-08-25 Jaqueline Scott Asthma inhaler kit adapted to make sound upon inhalation and exhalation
EP2662472B1 (en) 2009-03-31 2019-02-27 Boehringer Ingelheim International Gmbh Method for coating a surface of a component
US9265910B2 (en) 2009-05-18 2016-02-23 Boehringer Ingelheim International Gmbh Adapter, inhalation device, and nebulizer
US8985101B2 (en) 2009-05-21 2015-03-24 Microdose Therapeutx, Inc. Method and device for clamping a blister within a dry powder inhaler
WO2010135672A1 (en) * 2009-05-21 2010-11-25 Microdose Therapeutx, Inc. Rotary cassette system for dry powder inhaler
US20110000481A1 (en) * 2009-07-01 2011-01-06 Anand Gumaste Nebulizer for infants and respiratory compromised patients
US20130255678A1 (en) 2009-07-01 2013-10-03 Microdose Therapeutx, Inc. Nebulizer for infants and respiratory compromised patients
US9180263B2 (en) * 2009-07-01 2015-11-10 Microdose Therapeutx, Inc. Laboratory animal pulmonary dosing device
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
PE20130036A1 (en) 2009-11-25 2013-02-03 Boehringer Ingelheim Int Nebulizer
EP2504051B1 (en) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Nebulizer
CN104338219B (en) * 2010-01-05 2017-10-24 微剂量治疗技术公司 inhalation device and method
WO2011083377A1 (en) 2010-01-07 2011-07-14 Koninklijke Philips Electronics N.V. Respiratory drug delivery apparatus including a feedback and compliance device
US20130269684A1 (en) 2012-04-16 2013-10-17 Dance Pharmaceuticals, Inc. Methods and systems for supplying aerosolization devices with liquid medicaments
US9180261B2 (en) 2010-01-12 2015-11-10 Dance Biopharm Inc. Preservative free insulin formulations and systems and methods for aerosolizing
GB201006736D0 (en) 2010-04-22 2010-06-09 Mian Omar Gas flow indicator
US20110307039A1 (en) * 2010-06-14 2011-12-15 Cornell Thomas H Device, method and system for treatment of sinusitis
JP5874724B2 (en) 2010-06-24 2016-03-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Nebulizer
CA3114582A1 (en) 2010-12-22 2012-06-28 Syqe Medical Ltd. Method and system for drug delivery
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
EP2694220B1 (en) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medical device comprising a container
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
BR112014004921B1 (en) 2011-09-07 2020-12-08 Concentrx Pharmaceuticals, Inc. dry powder inhalation device
WO2013152894A1 (en) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Atomiser with coding means
US20130269694A1 (en) * 2012-04-16 2013-10-17 Dance Pharmaceuticals, Inc. Inhaler controlled by mobile device
EP3767632A1 (en) 2012-06-25 2021-01-20 Gecko Health Innovations, Inc. Devices, systems, and methods for adherence monitoring and patient interaction
EP2903672B1 (en) 2012-10-04 2018-01-10 Boehringer Ingelheim International GmbH System, method and use for training an inhalation process
EP2938376A4 (en) 2012-12-27 2017-01-25 Kaleo, Inc. Devices, systems and methods for locating and interacting with medicament delivery systems
US20140251321A1 (en) * 2013-03-07 2014-09-11 Jonah Henry Benson Inhaler mouthpiece
EP2968800B1 (en) 2013-03-15 2017-12-20 Chris V. Ciancone Inhaler spacer and storage apparatus
PL2835146T3 (en) 2013-08-09 2021-04-06 Boehringer Ingelheim International Gmbh Nebulizer
EP3030298B1 (en) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nebulizer
AU2014312428B2 (en) 2013-08-28 2018-10-11 Gecko Health Innovations, Inc. Devices, systems, and methods for adherence monitoring and devices, systems, and methods for monitoring use of consumable dispensers
ES2749050T3 (en) 2014-04-07 2020-03-18 Boehringer Ingelheim Int Inhalation training device and system to implement a patient's inhalation process
PL3129087T3 (en) 2014-04-07 2020-09-21 Boehringer Ingelheim International Gmbh Method, electronic device, inhalation training system for practicing and/or controlling an inhalation process of a patient
WO2015169732A1 (en) 2014-05-07 2015-11-12 Boehringer Ingelheim International Gmbh Container, nebulizer and use
EP3139984B1 (en) 2014-05-07 2021-04-28 Boehringer Ingelheim International GmbH Nebulizer
ES2957901T3 (en) 2014-05-07 2024-01-29 Boehringer Ingelheim Int Container and indicator device and nebulizer
CA2953082C (en) * 2014-06-30 2023-07-11 Syqe Medical Ltd. Flow regulating inhaler device
US11298477B2 (en) 2014-06-30 2022-04-12 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
EP3160565B1 (en) 2014-06-30 2021-08-18 Syqe Medical Ltd. Devices and systems for pulmonary delivery of active agents
AU2015283589B2 (en) 2014-06-30 2019-09-12 Syqe Medical Ltd. Method and device for vaporization and inhalation of isolated substances
KR20230117250A (en) 2014-06-30 2023-08-07 사이키 메디컬 엘티디. Drug dose cartridge for an inhaler device
IL273507B1 (en) 2014-06-30 2024-02-01 Syqe Medical Ltd Methods, devices and systems for pulmonary delivery of active agents
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone
JP6717833B2 (en) 2015-01-22 2020-07-08 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． Intake assistance with assigned functions
JP2018504964A (en) * 2015-01-23 2018-02-22 サンド・アクチエンゲゼルシヤフト Apparatus and method for generating a flow profile
US20170014584A1 (en) * 2015-07-15 2017-01-19 Prakash Mehta Inhaler mouthpiece
US20210128848A1 (en) * 2015-07-15 2021-05-06 Prakash Mehta Inhaler mouthpiece device
ES2745552T3 (en) 2015-07-20 2020-03-02 Pearl Therapeutics Inc Aerosol delivery systems
CA3009599A1 (en) 2016-01-06 2017-07-13 Syqe Medical Ltd. Low dose therapeutic treatment
MA43782A (en) * 2016-03-31 2021-04-28 Chiesi Farm Spa AEROSOL INHALATION DEVICE
JP7231410B2 (en) 2016-04-12 2023-03-01 バイオコープ プロダクション エス．アー． Metered dose inhaler add-on device, adherence improvement system, and method for improved adherence for use in metered dose inhalers
WO2017181228A1 (en) * 2016-04-18 2017-10-26 Telethon Kids Institute Spacer device for an inhaler
GB2556016A (en) * 2016-06-20 2018-05-23 Smartair Medical Ltd Device for monitoring medication intake
US10238821B2 (en) 2016-10-11 2019-03-26 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
JP6955016B2 (en) * 2016-10-11 2021-10-27 マイクロドース セラピューテクス，インコーポレイテッド Inhaler and how to use it
JP2020507841A (en) 2017-01-17 2020-03-12 カレオ，インコーポレイテッド Drug delivery device with wireless connection and event detection
EP3600504B1 (en) 2017-03-28 2023-07-12 Concentrx Pharmaceuticals, Inc. Device for delivering dry powder medicaments
CA3060820A1 (en) * 2017-04-18 2018-10-25 Inspiring Pty Ltd Dry powder inhaler and spacer device for a dry powder inhaler
CN110831647B (en) * 2017-04-18 2022-02-01 励志私人有限公司 Spacer for atomizer
CA2981322A1 (en) * 2017-10-03 2019-04-03 Smart Rs Inc. Improved adapter for drug delivery in a ventilator circuit
FR3081104B1 (en) * 2018-05-18 2020-05-15 Aptar France Sas FLUID PRODUCT DISPENSING DEVICE.
US11929160B2 (en) 2018-07-16 2024-03-12 Kaleo, Inc. Medicament delivery devices with wireless connectivity and compliance detection

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2865370A (en) * 1957-09-06 1958-12-23 Birch & Gattone Inc Dispensing adaptor for disposable aerosol units
YU41046B (en) * 1974-08-22 1986-10-31 Schering Ag Medicine inholating device
US4470412A (en) 1982-03-19 1984-09-11 Trutek Research, Inc. Inhalation valve
US4581013A (en) * 1982-04-19 1986-04-08 Jane C. A. Hayes Doser for orally administering medicine
US4790305A (en) * 1986-06-23 1988-12-13 The Johns Hopkins University Medication delivery system
US4926852B1 (en) * 1986-06-23 1995-05-23 Univ Johns Hopkins Medication delivery system phase one
US4792333A (en) * 1986-11-04 1988-12-20 Strawdose, Inc. Unit dose drug package and administering device
US4832015A (en) 1988-05-19 1989-05-23 Trudell Medical Pediatric asthmatic inhaler
US5020527A (en) 1990-02-20 1991-06-04 Texax-Glynn Corporation Inhaler device with counter/timer means
US5042467A (en) * 1990-03-28 1991-08-27 Trudell Medical Medication inhaler with fitting having a sonic signalling device
US5363842A (en) 1991-12-20 1994-11-15 Circadian, Inc. Intelligent inhaler providing feedback to both patient and medical professional
GB9203761D0 (en) 1992-02-21 1992-04-08 Innovata Biomed Ltd Inhaler
DE4208880A1 (en) * 1992-03-19 1993-09-23 Boehringer Ingelheim Kg SEPARATOR FOR POWDER INHALATORS
US5284133A (en) 1992-07-23 1994-02-08 Armstrong Pharmaceuticals, Inc. Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means
RU2071789C1 (en) * 1993-05-26 1997-01-20 Владимир Николаевич Абросимов Device for carrying out aerosol therapy
US5505195A (en) * 1993-09-16 1996-04-09 Medtrac Technologies Inc. Dry powder inhalant device with dosage and air flow monitor
SE9303155D0 (en) 1993-09-27 1993-09-27 Astra Ab Face mask
US6390088B1 (en) * 1993-12-13 2002-05-21 Boehringer Ingelheim Kg Aerosol inhaler
PT101450B (en) * 1994-02-02 1999-11-30 Hovione Produtos Farmaceuticos NEW INHALATION DEVICE
EP0667168B1 (en) * 1994-02-14 2000-06-21 Aradigm Corporation An inhalation training device
US5848588A (en) * 1994-05-25 1998-12-15 Trudell Medical Group Backpiece for receiving an MDI adapter in an aerosolization spacer
CA2124410A1 (en) * 1994-05-26 1995-11-27 Jean-Paul Praud Device for the simultaneous delivery of beta 2 agonists and oxygen to a patient
US5477849A (en) * 1994-05-31 1995-12-26 Fry; Stephen Spacer for medication inhaler
US5482030A (en) 1994-06-13 1996-01-09 Klein; David Aerosol and non-aerosol spray counter
GB9421687D0 (en) 1994-10-27 1994-12-14 Aid Medic Ltd Dosimetric spacer
US5522380A (en) * 1995-01-18 1996-06-04 Dwork; Paul Metered dose medication adaptor with improved incentive spirometer
US5571246A (en) * 1995-02-16 1996-11-05 Alldredge; Andrew L. Collapsible metered dose inhaler
GB9513218D0 (en) * 1995-06-29 1995-09-06 Fisons Plc Inhalation device and method
US5780058A (en) * 1995-07-21 1998-07-14 Alza Corporation Oral delivery of discrete units
US5746197A (en) * 1995-08-18 1998-05-05 Williams; Jeffery W. Extension for metered dose inhaler
AU7726096A (en) * 1995-11-15 1997-06-05 Regents Of The University Of Minnesota System for detecting target respiratory flow rates
US5797392C1 (en) * 1996-01-22 2001-01-09 Direct Haler As Inhaler
US5839430A (en) * 1996-04-26 1998-11-24 Cama; Joseph Combination inhaler and peak flow rate meter
US6158676A (en) * 1996-06-21 2000-12-12 Hughes Technology Group, L.L.C. Micro-atomizing device
GB9626263D0 (en) * 1996-12-18 1997-02-05 Innovata Biomed Ltd Powder inhaler
GB9706121D0 (en) * 1997-03-25 1997-05-14 Bespak Plc Inhalation device
US5794612A (en) * 1997-04-02 1998-08-18 Aeromax Technologies, Inc. MDI device with ultrasound sensor to detect aerosol dispensing
US6085742A (en) * 1997-04-02 2000-07-11 Aeromax Technologies, Inc. Intrapulmonary delivery device
US6394085B1 (en) * 1997-09-25 2002-05-28 Norton Healthcare Ltd. Inhaler spacer
US6470882B1 (en) * 1997-09-29 2002-10-29 Michael T. Newhouse Pernasal application of aerosol medication
US5855202A (en) * 1997-10-08 1999-01-05 Andrade; Joseph R. Aerosol holding chamber for a metered-dose inhaler
US5954047A (en) * 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
US6014972A (en) * 1997-12-11 2000-01-18 Thayer Medical Corporation Dry drug particle delivery system and method for ventilator circuits
US6358058B1 (en) 1998-01-30 2002-03-19 1263152 Ontario Inc. Aerosol dispensing inhaler training device
US6202643B1 (en) * 1998-02-23 2001-03-20 Thayer Medical Corporation Collapsible, disposable MDI spacer and method
USD412979S (en) * 1998-02-27 1999-08-17 Diemolding Corporation Metered dose inhaler spacer
CN2320270Y (en) * 1998-03-10 1999-05-26 王少廉 Oral-protecting spatula inhaling aid for quantitative aerosol
US6578571B1 (en) 1998-04-20 2003-06-17 Infamed Ltd. Drug delivery device and methods therefor
US6142146A (en) 1998-06-12 2000-11-07 Microdose Technologies, Inc. Inhalation device
KR100561223B1 (en) 1998-06-12 2006-03-15 마이크로도스 테크놀로지즈 인코포레이티드 Metering, packaging and delivery of pharmaceuticals and drugs
US6260549B1 (en) * 1998-06-18 2001-07-17 Clavius Devices, Inc. Breath-activated metered-dose inhaler
US6257231B1 (en) * 1998-12-03 2001-07-10 Ferraris Medical, Inc. Aerosol enhancement
US6202642B1 (en) * 1999-04-23 2001-03-20 Medtrac Technologies, Inc. Electronic monitoring medication apparatus and method
DE19944208C1 (en) * 1999-09-15 2001-09-06 Transmit Technologietransfer Combination mouthpiece for treating oxygen insufficiency in pulmonary hypertension and chronic obstructive pulmonary disease, comprises aerosol duct for supplying drug and inlet for receiving oxygen tube adapter
US6240917B1 (en) * 1999-12-20 2001-06-05 Joseph R. Andrade Aerosol holding chamber for a metered-dose inhaler
WO2001058514A1 (en) * 2000-02-11 2001-08-16 Profile Respiratory Systems Limited Drug delivery apparatus
US20020000225A1 (en) * 2000-06-02 2002-01-03 Carlos Schuler Lockout mechanism for aerosol drug delivery devices
US6684880B2 (en) * 2001-12-04 2004-02-03 Hewlett-Packard Development Company, L.P. Applicator for dispensing bioactive compositions and methods for using the same

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