WO2003024897A3 - Methods and apparatus for coating surfaces - Google Patents

Methods and apparatus for coating surfaces Download PDF

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Publication number
WO2003024897A3
WO2003024897A3 PCT/US2002/029569 US0229569W WO03024897A3 WO 2003024897 A3 WO2003024897 A3 WO 2003024897A3 US 0229569 W US0229569 W US 0229569W WO 03024897 A3 WO03024897 A3 WO 03024897A3
Authority
WO
WIPO (PCT)
Prior art keywords
thioethers
amphiphilic
controlling
thioether
coating surfaces
Prior art date
Application number
PCT/US2002/029569
Other languages
French (fr)
Other versions
WO2003024897A2 (en
Inventor
Jeffrey A Hubbell
Jane P Bearinger
Alessandro Napoli
Marcus Textor
Nicola Tirelli
Original Assignee
Eidgenoess Tech Hochschule
Univ Zuerich
Jeffrey A Hubbell
Jane P Bearinger
Alessandro Napoli
Marcus Textor
Nicola Tirelli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eidgenoess Tech Hochschule, Univ Zuerich, Jeffrey A Hubbell, Jane P Bearinger, Alessandro Napoli, Marcus Textor, Nicola Tirelli filed Critical Eidgenoess Tech Hochschule
Priority to EP02780316A priority Critical patent/EP1441865A4/en
Priority to CA002460928A priority patent/CA2460928A1/en
Priority to MXPA04002554A priority patent/MXPA04002554A/en
Publication of WO2003024897A2 publication Critical patent/WO2003024897A2/en
Publication of WO2003024897A3 publication Critical patent/WO2003024897A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Abstract

The present invention provides methods and apparatus for coating surfaces with specially designed thioethers and amphiphilic thioethers that reduce protein adsorption and/or cell adhesion. This reduction may be achieved, for example, by controlling the spacing or length of pendant chains or hydrophilic blocks in an amphiphilic thioether. Techniques for determining spacing include adsorbing the thioether from a solution or a colloidal suspension, or controlling the degree of polymerization of the thioether. Techniques for controlling the length of the pendant chains include controlling the degree of polymerization of the pendant chains. Multiblock copolymers of poly(propylene sulfide) and poly(ethylene glycol) ('PPS-PEG') represent an exemplary family of amphiphilic thioethers. Methods for coating surfaces with amphiphilic thioethers are also provided.
PCT/US2002/029569 2001-09-18 2002-09-18 Methods and apparatus for coating surfaces WO2003024897A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP02780316A EP1441865A4 (en) 2001-09-18 2002-09-18 Methods and apparatus for coating surfaces to reduce protein adsorption and cell adhesion and present ligands
CA002460928A CA2460928A1 (en) 2001-09-18 2002-09-18 Methods and apparatus for coating surfaces
MXPA04002554A MXPA04002554A (en) 2001-09-18 2002-09-18 Methods and apparatus for coating surfaces to reduce protein adsorption and cell adhesion and present ligands.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32335301P 2001-09-18 2001-09-18
US60/323,353 2001-09-18

Publications (2)

Publication Number Publication Date
WO2003024897A2 WO2003024897A2 (en) 2003-03-27
WO2003024897A3 true WO2003024897A3 (en) 2004-02-26

Family

ID=23258850

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/029569 WO2003024897A2 (en) 2001-09-18 2002-09-18 Methods and apparatus for coating surfaces

Country Status (5)

Country Link
US (1) US7427410B2 (en)
EP (1) EP1441865A4 (en)
CA (1) CA2460928A1 (en)
MX (1) MXPA04002554A (en)
WO (1) WO2003024897A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2460862A1 (en) 2001-09-18 2003-03-27 Eidgenossische Technische Hochschule Zurich Methods and apparatus for patterning a surface
US20030215723A1 (en) 2002-04-19 2003-11-20 Bearinger Jane P. Methods and apparatus for selective, oxidative patterning of a surface
US20050180957A1 (en) * 2004-01-16 2005-08-18 Scharp David W. Method of using fibrin-bound angiogenic factors to stimulate vascularization of transplant site of encapsulated cells
DE102004043908A1 (en) 2004-09-10 2006-03-30 GRÄTER, Stefan Surface-structured polymeric substrates and their preparation
US7597950B1 (en) * 2005-02-28 2009-10-06 Massachusetts Institute Of Technology Nanoparticles having sub-nanometer features
EP2298829B1 (en) * 2005-05-31 2017-09-20 École Polytechnique Fédérale de Lausanne (EPFL) Triblock copolymers for cytoplasmic delivery of gene-based drugs
US20090191351A1 (en) * 2008-01-28 2009-07-30 Gm Global Technology Operations, Inc. Fuel cell bipolar plate with variable surface properties
EP2278938A4 (en) * 2008-04-22 2013-12-11 Univ Colorado Regents Thiol-vinyl and thiol-yne systems for shape memory polymers
GB0816783D0 (en) 2008-09-15 2008-10-22 Carmeda Ab Immobilised biological entities
US20100096327A1 (en) * 2008-09-19 2010-04-22 Gin Douglas L Polymer coatings that resist adsorption of proteins
WO2010068432A1 (en) * 2008-11-25 2010-06-17 Ecole Polytechnique Federale De Lausanne (Epfl) Block copolymers and uses thereof
EP2260995A1 (en) * 2009-06-12 2010-12-15 Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V. Surface-structured polyurethane substrates and methods for producing the same
GB201004101D0 (en) 2010-03-12 2010-04-28 Carmeda Ab Immobilised biological entities
TWI487543B (en) 2011-12-12 2015-06-11 Ind Tech Res Inst Brush polymer and medical use thereof
US10711106B2 (en) 2013-07-25 2020-07-14 The University Of Chicago High aspect ratio nanofibril materials
US9044200B1 (en) 2013-12-17 2015-06-02 Google Inc. Noble metal surface treatment to improve adhesion in bio-compatible devices
WO2015101777A1 (en) * 2014-01-06 2015-07-09 Nanoco Technologies Ltd Surface-modified nanoparticles
KR102194518B1 (en) 2016-03-28 2020-12-23 엔테그리스, 아이엔씨. Hydrogenated isotope-rich boron trifluoride dopant source gas composition
US11198831B2 (en) 2019-01-31 2021-12-14 Kvi Llc Lubricant for a device
CN114917414B (en) * 2022-04-26 2023-09-29 东南大学 Multifunctional composite coating for preparing magnesium alloy heart stent material and preparation method thereof

Citations (7)

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Publication number Priority date Publication date Assignee Title
US4795660A (en) * 1985-05-10 1989-01-03 Akzo N.V. Metallized polymer compositions, processes for their preparation and their uses
US5030352A (en) * 1990-01-25 1991-07-09 Purdue Research Foundation Coated media for chromatography
US5688855A (en) * 1995-05-01 1997-11-18 S.K.Y. Polymers, Inc. Thin film hydrophilic coatings
US5821343A (en) * 1996-04-25 1998-10-13 Medtronic Inc Oxidative method for attachment of biomolecules to surfaces of medical devices
US6306165B1 (en) * 1996-09-13 2001-10-23 Meadox Medicals ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin
US6358557B1 (en) * 1999-09-10 2002-03-19 Sts Biopolymers, Inc. Graft polymerization of substrate surfaces
US6562398B1 (en) * 1998-05-27 2003-05-13 Commonwealth Scientific And Industrial Research Organization Molecular coatings

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013855A (en) * 1996-08-06 2000-01-11 United States Surgical Grafting of biocompatible hydrophilic polymers onto inorganic and metal surfaces
US5863650A (en) * 1997-05-05 1999-01-26 Bioengineered Materials, Inc. Interfacial coatings
US6958212B1 (en) * 1999-02-01 2005-10-25 Eidgenossische Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
WO2002055185A2 (en) * 2000-10-19 2002-07-18 Eidgenoess Tech Hochschule Block copolymers for multifunctional self-assembled systems
CA2460862A1 (en) 2001-09-18 2003-03-27 Eidgenossische Technische Hochschule Zurich Methods and apparatus for patterning a surface

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795660A (en) * 1985-05-10 1989-01-03 Akzo N.V. Metallized polymer compositions, processes for their preparation and their uses
US5030352A (en) * 1990-01-25 1991-07-09 Purdue Research Foundation Coated media for chromatography
US5688855A (en) * 1995-05-01 1997-11-18 S.K.Y. Polymers, Inc. Thin film hydrophilic coatings
US5821343A (en) * 1996-04-25 1998-10-13 Medtronic Inc Oxidative method for attachment of biomolecules to surfaces of medical devices
US6306165B1 (en) * 1996-09-13 2001-10-23 Meadox Medicals ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin
US6562398B1 (en) * 1998-05-27 2003-05-13 Commonwealth Scientific And Industrial Research Organization Molecular coatings
US6358557B1 (en) * 1999-09-10 2002-03-19 Sts Biopolymers, Inc. Graft polymerization of substrate surfaces

Also Published As

Publication number Publication date
CA2460928A1 (en) 2003-03-27
EP1441865A2 (en) 2004-08-04
US20030133963A1 (en) 2003-07-17
EP1441865A4 (en) 2010-04-07
MXPA04002554A (en) 2004-05-31
US7427410B2 (en) 2008-09-23
WO2003024897A2 (en) 2003-03-27

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