WO2003026559A3 - Nasal nebulizer - Google Patents

Nasal nebulizer Download PDF

Info

Publication number
WO2003026559A3
WO2003026559A3 PCT/US2002/031450 US0231450W WO03026559A3 WO 2003026559 A3 WO2003026559 A3 WO 2003026559A3 US 0231450 W US0231450 W US 0231450W WO 03026559 A3 WO03026559 A3 WO 03026559A3
Authority
WO
WIPO (PCT)
Prior art keywords
nebulizer
nasal nebulizer
nasal
breathing
user
Prior art date
Application number
PCT/US2002/031450
Other languages
French (fr)
Other versions
WO2003026559A2 (en
Inventor
Marc Giroux
Original Assignee
Kurve Technology Inc
Marc Giroux
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kurve Technology Inc, Marc Giroux filed Critical Kurve Technology Inc
Priority to AU2002340083A priority Critical patent/AU2002340083A1/en
Priority to JP2003530198A priority patent/JP4795637B2/en
Priority to EP02778422.2A priority patent/EP1450885B1/en
Publication of WO2003026559A2 publication Critical patent/WO2003026559A2/en
Publication of WO2003026559A3 publication Critical patent/WO2003026559A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0618—Nose

Abstract

A nebulizer (25) and a method of breathing using the nebulizer (25) is described. The nebulizer (25) and breathing techniques are capable of delivering medication into the sinus cavity of a user.
PCT/US2002/031450 2001-09-28 2002-09-30 Nasal nebulizer WO2003026559A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2002340083A AU2002340083A1 (en) 2001-09-28 2002-09-30 Nasal nebulizer
JP2003530198A JP4795637B2 (en) 2001-09-28 2002-09-30 Nose nebulizer
EP02778422.2A EP1450885B1 (en) 2001-09-28 2002-09-30 Nasal nebulizer

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US32597101P 2001-09-28 2001-09-28
US60/325,971 2001-09-28
US37942802P 2002-05-09 2002-05-09
US60/379,428 2002-05-09

Publications (2)

Publication Number Publication Date
WO2003026559A2 WO2003026559A2 (en) 2003-04-03
WO2003026559A3 true WO2003026559A3 (en) 2003-11-06

Family

ID=26985188

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/031450 WO2003026559A2 (en) 2001-09-28 2002-09-30 Nasal nebulizer

Country Status (5)

Country Link
US (4) US7231919B2 (en)
EP (1) EP1450885B1 (en)
JP (2) JP4795637B2 (en)
AU (1) AU2002340083A1 (en)
WO (1) WO2003026559A2 (en)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7117033B2 (en) * 2000-05-08 2006-10-03 Brainsgate, Ltd. Stimulation for acute conditions
AU2002340083A1 (en) 2001-09-28 2003-04-07 Kurve Technology, Inc Nasal nebulizer
EP1494732B1 (en) 2002-03-20 2008-01-30 MannKind Corporation Inhalation apparatus
US7684859B2 (en) * 2002-04-25 2010-03-23 Brainsgate Ltd. Stimulation of the OTIC ganglion for treating medical conditions
US8122881B2 (en) * 2002-05-09 2012-02-28 Kurve Technology, Inc. Particle dispersion device for nasal delivery
US7561919B2 (en) * 2002-11-14 2009-07-14 Brainsgate Ltd. SPG stimulation via the greater palatine canal
US8010189B2 (en) * 2004-02-20 2011-08-30 Brainsgate Ltd. SPG stimulation for treating complications of subarachnoid hemorrhage
US8055347B2 (en) 2005-08-19 2011-11-08 Brainsgate Ltd. Stimulation for treating brain events and other conditions
US8109266B2 (en) 2004-02-20 2012-02-07 Pneumoflex Systems, Llc Nebulizer having flow meter function
US9022027B2 (en) 2004-02-20 2015-05-05 Pneumoflex Systems, Llc Nebulizer with intra-oral vibrating mesh
US9233245B2 (en) 2004-02-20 2016-01-12 Brainsgate Ltd. SPG stimulation
DK1786784T3 (en) 2004-08-20 2011-02-14 Mannkind Corp Catalysis of diketopiperazine synthesis
PL2322180T3 (en) 2004-08-23 2015-10-30 Mannkind Corp Diketopiperazine salts for drug delivery
WO2006021957A2 (en) * 2004-08-23 2006-03-02 Brainsgate Ltd. Concurrent bilateral spg modulation
CN104324366B (en) 2005-09-14 2016-10-05 曼金德公司 Method for preparation of drug based on improving the active agent affinity to crystalline microparticle surfaces
WO2007035913A2 (en) * 2005-09-21 2007-03-29 Kurve Technology, Inc. Medicament delivery control, monitoring, and reporting system and method
US20070137648A1 (en) * 2005-12-16 2007-06-21 Pneumoflex Systems, Llc Intraoral Nebulizer Providing Air Curtains
US7681569B2 (en) * 2006-01-23 2010-03-23 Lytesyde, Llc Medical liquid processor apparatus and method
GB0602980D0 (en) * 2006-02-14 2006-03-29 Optinose As Delivery device and method
MX360812B (en) 2006-02-22 2018-11-16 Mannkind Corp A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent.
WO2008014543A1 (en) 2006-08-04 2008-02-07 Resmed Ltd Nasal prongs for mask system
WO2008017575A1 (en) * 2006-08-07 2008-02-14 Bang & Olufsen Medicom A/S An inhaler and a method of dispensing medication to a person
US20090210026A1 (en) * 2006-08-17 2009-08-20 Brainsgate Ltd. Spg stimulation for enhancing neurogenesis and brain metabolism
CA2698137A1 (en) 2006-08-30 2008-03-06 Kurve Technology, Inc. Aerosol generating and delivery device
EP2112923A1 (en) 2007-01-22 2009-11-04 Targacept Inc. Intranasal, buccal, and sublingual administration of metanicotine analogs
GB2448193A (en) 2007-04-05 2008-10-08 Optinose As Nasal delivery device
WO2008131043A1 (en) * 2007-04-20 2008-10-30 Robert Wieden Inhaler adapter
US7860569B2 (en) 2007-10-18 2010-12-28 Brainsgate, Ltd. Long-term SPG stimulation therapy for prevention of vascular dementia
CN101980738A (en) * 2008-02-07 2011-02-23 华盛顿大学 Circumferential aerosol device
US7981097B2 (en) * 2008-03-27 2011-07-19 Paoli Jr Alexander Delli Medical device for the treatment and prevention of eye and respiratory tract conditions
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
DE202009018480U1 (en) 2008-06-13 2012-01-26 Mannkind Corp. Dry powder inhaler and drug delivery system
MX2010014240A (en) 2008-06-20 2011-03-25 Mankind Corp An interactive apparatus and method for real-time profiling of inhalation efforts.
TWI532497B (en) 2008-08-11 2016-05-11 曼凱公司 Use of ultrarapid acting insulin
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US20100168602A1 (en) * 2008-12-30 2010-07-01 Searete Llc Methods and systems for presenting an inhalation experience
US20100169259A1 (en) * 2008-12-30 2010-07-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for presenting an inhalation experience
US20100163036A1 (en) * 2008-12-30 2010-07-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for presenting an inhalation experience
US20100163033A1 (en) * 2008-12-30 2010-07-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for presenting an inhalation experience
US8712794B2 (en) * 2008-12-30 2014-04-29 The Invention Science Fund I, Llc Methods and systems for presenting an inhalation experience
US8738395B2 (en) * 2008-12-30 2014-05-27 The Invention Science Fund I, Llc Methods and systems for presenting an inhalation experience
US20100163034A1 (en) * 2008-12-30 2010-07-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for presenting an inhalation experience
US20100163025A1 (en) * 2008-12-30 2010-07-01 Searete Llc Methods and systems for presenting an inhalation experience
US20100168525A1 (en) * 2008-12-30 2010-07-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for presenting an inhalation experience
US20100169260A1 (en) * 2008-12-30 2010-07-01 Searete Llc Methods and systems for presenting an inhalation experience
US20100163029A1 (en) * 2008-12-30 2010-07-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method for administering an inhalable compound
US8725529B2 (en) * 2008-12-30 2014-05-13 The Invention Science Fund I, Llc Methods and systems for presenting an inhalation experience
US8706518B2 (en) * 2008-12-30 2014-04-22 The Invention Science Fund I, Llc Methods and systems for presenting an inhalation experience
US20100168529A1 (en) * 2008-12-30 2010-07-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for presenting an inhalation experience
US8694330B2 (en) * 2008-12-30 2014-04-08 The Invention Science Fund I, Llc Methods and systems for presenting an inhalation experience
US20100163038A1 (en) * 2008-12-30 2010-07-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for presenting an inhalation experience
CA2753645C (en) * 2009-02-27 2016-07-26 Pari Pharma Gmbh Method for operating an aerosol inhalation device and aerosol inhalation device
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
CA2835771C (en) * 2009-03-18 2017-01-24 Incarda Therapeutics, Inc. Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration
KR101875969B1 (en) 2009-06-12 2018-07-06 맨카인드 코포레이션 Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
DK3108966T3 (en) 2010-06-18 2020-01-02 Boehringer Ingelheim Int INHALER
RU2571331C1 (en) 2010-06-21 2015-12-20 Маннкайнд Корпорейшн Systems and methods for dry powder drug delivery
US9452270B2 (en) 2011-01-20 2016-09-27 Pneumoflex Systems, Llc Nebulizer having replaceable nozzle assembly and suction line
US20140202457A1 (en) 2011-01-20 2014-07-24 Pneumoflex Systems, Llc Metered dose nebulizer
US8671934B2 (en) 2011-01-20 2014-03-18 Pneumoflex Systems, Llc Nebulizer that is activated by negative inspiratory pressure
CA2828884C (en) 2011-03-03 2021-04-27 Impel Neuropharma, Inc. Nasal drug delivery device
BR122020008875B8 (en) 2011-04-01 2022-12-06 Mannkind Corp BLISTER PACKAGING AND METHOD OF MANUFACTURING A BLISTER PACKAGE
JP2012217500A (en) * 2011-04-05 2012-11-12 Morita Mfg Co Ltd Spraying apparatus for otorhinolaryngology
JP6645735B2 (en) 2011-05-09 2020-02-14 インペル ニューロファーマ インコーポレイテッド Nose delivery nozzle
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
KR102264177B1 (en) 2012-07-12 2021-06-11 맨카인드 코포레이션 Dry powder drug delivery systems and methods
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
BR112015023168B1 (en) 2013-03-15 2021-08-10 Mannkind Corporation COMPOSITION OF 3,6-BIS(N-FUMARYL-4-AMINOBUTYL)-2,5-CRYSTALLINE DICETOPIPERAZINE, METHOD OF PRODUCTION OF 3,6-BIS(N-FUMARYL-4-AMINOBUTYL)-2,5-DICETOPIPERAZINE PARTICLES AND USE OF A CRYSTALLINE DICETOPIPERAZINE COMPOSITION
JP2016520378A (en) 2013-04-28 2016-07-14 インペル ニューロファーマ インコーポレイテッド Medical unit dose container
CN114848614A (en) 2013-07-18 2022-08-05 曼金德公司 Heat stable dry powder pharmaceutical compositions and methods
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
EP2878335B1 (en) 2013-11-10 2018-01-03 Brainsgate Ltd. Implant and delivery system for neural stimulator
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
FR3025110B1 (en) 2014-09-02 2016-12-23 Univ Francois-Rabelais De Tours NASAL FLUID SPRAY DEVICE
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2016159889A1 (en) 2015-04-02 2016-10-06 Hill-Rom Services Pte. Ltd. Manifold for respiratory device
EP3093043B1 (en) 2015-05-13 2018-11-14 Brainsgate Ltd. Implant and delivery system for neural stimulator
US11266799B2 (en) 2015-09-10 2022-03-08 Impel Neuropharma, Inc. In-line nasal delivery device
RU2768748C2 (en) 2016-02-01 2022-03-24 Инкарда Терапьютикс, Инк. Combination of electronic monitoring with inhalation pharmacological therapy for control of cardiac arrhythmias, including atrial fibrillation
CA3060702A1 (en) 2017-05-10 2018-11-15 Incarda Therapeutics, Inc. Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration
US11395887B2 (en) 2017-11-21 2022-07-26 Impel Pharmaceuticals Inc. Intranasal device with inlet interface
JP7191099B2 (en) 2017-11-21 2022-12-16 インペル ファーマシューティカルズ インコーポレイテッド intranasal device with dip tube
WO2019112495A1 (en) * 2017-12-05 2019-06-13 Maquet Critical Care Ab Piercing assembly and breathing conduit kit
RU2020125871A (en) 2018-01-05 2022-02-07 Импел Ньюрофарма, Инк. INTRANASAL DELIVERY OF DIHYDROERGOTAMINE USING A PRECISION DELIVERY DEVICE TO THE OLFACTORY REGION
US11278492B2 (en) 2018-01-05 2022-03-22 Impel Neuropharma, Inc. Intranasal delivery of olanzapine by precision olfactory device
WO2019183470A2 (en) 2018-03-22 2019-09-26 Incarda Therapeutics, Inc. A novel method to slow ventricular rate
US11517548B2 (en) 2018-07-19 2022-12-06 Impel Pharmaceuticals Inc. Respiratory tract delivery of levodopa and DOPA decarboxylase inhibitor for treatment of Parkinson's Disease
AU2019418744B2 (en) 2019-01-03 2023-08-03 Impel Pharmaceuticals Inc. Nasal drug delivery device
CN111696398A (en) * 2019-03-15 2020-09-22 中国石油化工股份有限公司 Immersion type virtual simulation training method for eliminating hidden danger of direct operation link of petrochemical enterprise
BR112021023049A8 (en) 2019-05-17 2022-10-18 Impel Neuropharma Inc SINGLE USE NASAL DISPENSING DEVICE
US11020384B2 (en) 2019-08-01 2021-06-01 Incarda Therapeutics, Inc. Antiarrhythmic formulation
WO2023135237A1 (en) 2022-01-14 2023-07-20 Cybin Irl Limited Tryptamine compositions and methods
WO2023156453A1 (en) 2022-02-15 2023-08-24 Cybin Irl Limited Phenethylamine derivatives, compositions, and methods of use
WO2023156450A1 (en) 2022-02-15 2023-08-24 Cybin Irl Limited Therapeutic phenethylamine compositions and methods of use
US20230310308A1 (en) 2022-03-17 2023-10-05 Marc Giroux Drug Delivery Systems, Apparatuses, and Methods
WO2023186963A1 (en) 2022-03-31 2023-10-05 Cybin Irl Limited Combination of nitrous oxide and 5-ht2a receptor agonists

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4461425A (en) * 1982-07-13 1984-07-24 Respiratory Care, Inc. Nebulizer system
US4809692A (en) * 1986-01-31 1989-03-07 Trudell Medical Pediatric asthmatic medication inhaler
US5203323A (en) * 1991-07-02 1993-04-20 Tritle Paul E Metered dose inhaler spacer device and associated cleaning brush
US5435282A (en) * 1994-05-19 1995-07-25 Habley Medical Technology Corporation Nebulizer
US5485828A (en) * 1992-04-29 1996-01-23 Hauser; Jean-Luc Portable device for micropulverization generated by ultrasound waves
US5577497A (en) * 1991-05-20 1996-11-26 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5755218A (en) * 1991-03-05 1998-05-26 Aradigm Corporation Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US5855202A (en) * 1997-10-08 1999-01-05 Andrade; Joseph R. Aerosol holding chamber for a metered-dose inhaler
US6112746A (en) * 1996-07-26 2000-09-05 Resmed Limited Nasal mask and mask cushion therefor
US6202643B1 (en) * 1998-02-23 2001-03-20 Thayer Medical Corporation Collapsible, disposable MDI spacer and method
US6240917B1 (en) * 1999-12-20 2001-06-05 Joseph R. Andrade Aerosol holding chamber for a metered-dose inhaler

Family Cites Families (139)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2603216A (en) 1952-07-15 Powder inhaler
US2503732A (en) 1949-01-28 1950-04-11 Wyeth Corp Inhalator
US2819716A (en) 1954-11-16 1958-01-14 Joseph B Miller Nebulizer for medicinal preparations
US2951644A (en) * 1958-01-03 1960-09-06 Ass For Physiologic Res Inc Dispensing device
US3155573A (en) 1958-05-06 1964-11-03 Benger Lab Ltd Inhalant composition and method of making same
GB1069048A (en) * 1964-02-10 1967-05-17 Devilbiss Co Method and apparatus for producing aerosols
US3362405A (en) * 1964-04-06 1968-01-09 Hamilton O. Hazel Method and apparatus for admixing gas with solid particles
FR1430243A (en) 1965-01-07 1966-03-04 Improvements to vaporizers, especially for perfumery
US3358844A (en) 1965-08-17 1967-12-19 Siemens Ag Device for increasing the total amount of separation of a vortex separator
US3762409A (en) 1970-11-03 1973-10-02 V Lester Nebulizer
US3858615A (en) * 1972-12-11 1975-01-07 Puritan Bennett Corp Flexible hose construction
US4069819A (en) 1973-04-13 1978-01-24 Societa Farmaceutici S.P.A. Inhalation device
US3973566A (en) 1975-01-13 1976-08-10 Syntex Puerto Rico Inc. Inhalation device
DE2537765B2 (en) 1975-08-25 1981-04-09 Siemens AG, 1000 Berlin und 8000 München Medical inhalation device for the treatment of diseases of the respiratory tract
US4150071A (en) * 1977-08-26 1979-04-17 Respiratory Care, Inc. Nebulizer
US4157368A (en) 1977-12-23 1979-06-05 Combustion Engineering, Inc. Vortex cooling tower
US4198969A (en) 1978-10-06 1980-04-22 Baxter Travenol Laboratories, Inc. Suction-operated nebulizer
DE2843756B2 (en) * 1978-10-06 1981-07-09 Hense GmbH & Co, 4930 Detmold Device for generating an aerosol
US4241877A (en) 1978-10-16 1980-12-30 Hughes Sciences Group, Inc. Stable vortex generating device
US4453542A (en) 1980-12-08 1984-06-12 Vortran Corporation Vortex-generating medical products
US4454880A (en) * 1982-05-12 1984-06-19 Rudolph Muto Nasal hood with open-bottom mixing chamber
FR2547737B1 (en) 1983-06-24 1988-04-08 Valois Sa PUSH-BUTTON FOR MEDICAL SPRAYER
US4554916A (en) 1983-07-27 1985-11-26 James Watt Rotary proportioning inhalator
AU3439884A (en) 1983-11-28 1985-06-13 Vortran Corp. Single inlet prepackaged inhaler
US4750650A (en) 1984-06-12 1988-06-14 Ling Carl P C Extended surface apparatus for use in dispensing liquids
US4972830A (en) 1985-07-31 1990-11-27 Vortran Medical Technology, Inc. Inhalation device and method
JPS62261842A (en) 1986-05-09 1987-11-14 Nippon Air Curtain Kk Artificial tornado generating mechanism and utilization thereof
US4809629A (en) * 1987-02-26 1989-03-07 Martinmaas Werner W Sail rig for a wind propelled vehicle
US5322057A (en) 1987-07-08 1994-06-21 Vortran Medical Technology, Inc. Intermittent signal actuated nebulizer synchronized to operate in the exhalation phase, and its method of use
EP0346417B1 (en) 1987-12-11 1994-10-05 DEUTSCHE FORSCHUNGSANSTALT FÜR LUFT- UND RAUMFAHRT e.V. Whirl nozzle for atomizing a liquid
FI82808C (en) 1987-12-31 1991-04-25 Etelae Haemeen Keuhkovammayhdi Ultraljudfinfördelningsanordning
US4809706A (en) 1988-01-13 1989-03-07 Watson Robert L Incentive inhalation spirometer apparatus
CA1325568C (en) 1988-06-24 1993-12-28 Pineway (Uk) Ltd. Eye-bathing devices
US4865027A (en) * 1988-09-27 1989-09-12 The University Of Michigan Non-rebreathing collapsible chamber continuous aerosol delivery system with infusion port
US4938209A (en) 1989-01-12 1990-07-03 Fry William J Mask for a nebulizer
SE466684B (en) 1989-03-07 1992-03-23 Draco Ab DEVICE INHALATOR AND PROCEDURE TO REGISTER WITH THE DEVICE INHALATOR MEDICATION
DE3907414A1 (en) 1989-03-08 1990-09-13 Hoechst Ag THE APPLICATION OF INHALED LOOP DIURETICS FOR THE TREATMENT OF ALLERGEN-INDUCED NASAL REACTIONS
GB8908647D0 (en) * 1989-04-17 1989-06-01 Glaxo Group Ltd Device
JP2922935B2 (en) 1989-08-11 1999-07-26 東興薬品工業株式会社 Disposable adapter for nasal spray container for viscous liquid
US4953545A (en) * 1989-10-18 1990-09-04 Mccarty Jerry Disposable respiratory medication dispersion chamber
IT1237118B (en) 1989-10-27 1993-05-18 Miat Spa MULTI-DOSE INHALER FOR POWDER DRUGS.
SG45171A1 (en) 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
IL98441A (en) 1990-06-14 1995-12-31 Rhone Poulenc Rorer Ltd Powder inhalers
GB9015077D0 (en) 1990-07-09 1990-08-29 Riker Laboratories Inc Inhaler
IT1243344B (en) 1990-07-16 1994-06-10 Promo Pack Sa MULTI-DOSE INHALER FOR POWDER MEDICATIONS
DE69127826T2 (en) 1990-12-17 1998-04-09 Minnesota Mining & Mfg INHALATION DEVICE
DE59107894D1 (en) * 1991-03-21 1996-07-11 Ritzau Pari Werk Gmbh Paul Nebulizers, in particular for use in devices for inhalation therapy
US5241954A (en) 1991-05-24 1993-09-07 Glenn Joseph G Nebulizer
JP3230056B2 (en) * 1991-07-02 2001-11-19 インヘイル・インコーポレーテッド Device for forming an aerosolized dose of a drug
GB9115340D0 (en) 1991-07-16 1991-08-28 Univ Leeds Nebuliser
US5165392A (en) 1991-07-16 1992-11-24 Small Jr John C Accuvent aerosol delivery system
US5954049A (en) * 1991-10-15 1999-09-21 Trudell Medical Limited Equine mask with MDI adapter
EP0539674B1 (en) * 1991-10-19 1996-06-12 Solvay Deutschland GmbH Aerosol generating system
DE9113446U1 (en) * 1991-10-29 1992-01-16 Kendall Medizinische Erzeugnisse Gmbh, 8425 Neustadt, De
US5476093A (en) * 1992-02-14 1995-12-19 Huhtamaki Oy Device for more effective pulverization of a powdered inhalation medicament
US5287847A (en) 1992-07-24 1994-02-22 Vortran Medical Technology, Inc. Universal nebulizer
EP0674533B1 (en) 1992-12-18 1999-03-10 Schering Corporation Inhaler for powdered medications
US5743250A (en) 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
GB9311892D0 (en) 1993-06-09 1993-07-28 Glaxo Wellcome Australia Ltd Device
US5349947A (en) * 1993-07-15 1994-09-27 Newhouse Michael T Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow
US5388574A (en) 1993-07-29 1995-02-14 Ingebrethsen; Bradley J. Aerosol delivery article
US5437267A (en) 1993-08-03 1995-08-01 Weinstein; Allan Device for delivering aerosol to the nasal membranes and method of use
US5322646A (en) 1993-08-03 1994-06-21 Amazing Things Simulated tornado humidifier
US5520167A (en) 1993-08-31 1996-05-28 The Brewer Company Nebulizer mask adaptor ring
IT1266794B1 (en) 1993-11-09 1997-01-21 Faustino Ballini MICRONIZED SHOWER DEVICE FOR WASHING THE NASAL AND NEIGHBORING CAVITIES
US5388564A (en) * 1994-01-05 1995-02-14 Islas; John J. Compound bow
US5479920A (en) 1994-03-01 1996-01-02 Vortran Medical Technology, Inc. Breath actuated medicinal aerosol delivery apparatus
DE69535897D1 (en) 1994-03-07 2009-01-22 Nektar Therapeutics Method and composition for the pulmonary delivery of insulin
CA2124410A1 (en) * 1994-05-26 1995-11-27 Jean-Paul Praud Device for the simultaneous delivery of beta 2 agonists and oxygen to a patient
CA2555600C (en) 1994-09-21 2008-01-29 Nektar Therapeutics Apparatus and methods for dispersing dry powder medicaments
GB9422821D0 (en) 1994-11-11 1995-01-04 Aid Medic Ltd Atomizer
DE19507410C2 (en) * 1995-03-03 1997-05-22 Gsf Forschungszentrum Umwelt Method and device for producing aerosols
US6085740A (en) 1996-02-21 2000-07-11 Aerogen, Inc. Liquid dispensing apparatus and methods
JPH08280809A (en) 1995-04-12 1996-10-29 Unisia Jecs Corp Nebulizing container for nasal cavity
US5724965A (en) 1995-06-06 1998-03-10 Respironics Inc. Nasal mask
US5584285A (en) 1995-06-07 1996-12-17 Salter Labs Breathing circuit apparatus for a nebulizer
US5586551A (en) 1995-07-17 1996-12-24 Hilliard; Kenneth R. Oxygen mask with nebulizer
US5588564A (en) 1995-08-21 1996-12-31 Hutson; Clifford L. Eye spray mist dispenser
US5711488A (en) 1995-10-13 1998-01-27 The Procter & Gamble Company High pressure swirl atomizer
US5875774A (en) 1996-01-05 1999-03-02 Sunrise Medical Hhg Inc. Nebulizer
GB2312379B (en) 1996-04-25 1999-11-17 Bespak Plc Improved inhalers
US5906198A (en) 1996-07-16 1999-05-25 Flickinger; William J. Nasal nebulizer
GB2318737B (en) * 1996-10-30 2000-06-14 Bespak Plc Improved inhalers
US5685291A (en) 1996-11-15 1997-11-11 Marsh; Jean Ann Nebulizer adapter system for premature babies
GB9626263D0 (en) 1996-12-18 1997-02-05 Innovata Biomed Ltd Powder inhaler
TW469832U (en) 1997-03-14 2001-12-21 Astra Ab Inhalation device
US5881720A (en) 1997-04-29 1999-03-16 The Procter & Gamble Company Method of delivering halotherapy
US6076520A (en) 1997-05-12 2000-06-20 Cooper; Emily L. Device for nasal therapeutic inhalation
US6119694A (en) 1997-07-24 2000-09-19 Respironics Georgia, Inc. Nasal mask and headgear
CA2212430A1 (en) 1997-08-07 1999-02-07 George Volgyesi Inhalation device
US6073629A (en) 1997-09-25 2000-06-13 Norton Healthcare Ltd. Inhaler spacer
US6394085B1 (en) 1997-09-25 2002-05-28 Norton Healthcare Ltd. Inhaler spacer
US6470882B1 (en) * 1997-09-29 2002-10-29 Michael T. Newhouse Pernasal application of aerosol medication
US5950623A (en) * 1997-10-16 1999-09-14 Ohmeda Inc. Adjustable pressure limiting valve for anesthesia breathing circuit
US5954047A (en) * 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
US6192876B1 (en) * 1997-12-12 2001-02-27 Astra Aktiebolag Inhalation apparatus and method
GB2334686B (en) 1998-02-26 2002-06-19 Medic Aid Ltd Nebuliser
CA2322193C (en) 1998-03-05 2006-10-24 Batelle Memorial Institute Pulmonary dosing system and method
US6113078A (en) 1998-03-18 2000-09-05 Lytesyde, Llc Fluid processing method
US6041776A (en) 1998-05-14 2000-03-28 Briggs, Iii; Stephen W. Medical nebulization device
US6500165B1 (en) 1998-10-29 2002-12-31 Steven R. Frank Active antisepsis device
US6158428A (en) * 1998-12-21 2000-12-12 We Pharmaceuticals Inc. Infant inhaler
CA2364009C (en) * 1999-03-03 2007-02-27 Per Gisle Djupesland Nasal delivery device
US6223744B1 (en) 1999-03-16 2001-05-01 Multi-Vet Ltd. Wearable aerosol delivery apparatus
WO2000058016A1 (en) 1999-03-31 2000-10-05 Shofner Engineering Associates, Inc. Controlled deliveries and depositions of pharmaceutical and other aerosolized masses
US6412488B1 (en) * 1999-05-12 2002-07-02 Respironics, Inc. Low contact nasal mask and system using same
ES2258458T3 (en) * 1999-05-20 2006-09-01 Kos Life Sciences, Inc. LOW FORCE SPRAYING AND LOW RETENTION ATOMIZATION SYSTEM.
US6468330B1 (en) 1999-06-14 2002-10-22 Innovatek, Inc. Mini-cyclone biocollector and concentrator
US6338443B1 (en) 1999-06-18 2002-01-15 Mercury Enterprises, Inc. High efficiency medical nebulizer
US6576224B1 (en) 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
CA2379073C (en) 1999-07-13 2007-04-03 Dominique Logeart Drill assembly for preparing a prosthetic crown-receiving tooth
US6367471B1 (en) 1999-11-01 2002-04-09 Sheffield Pharmaceuticals, Inc. Internal vortex mechanism for inhaler device
US6726659B1 (en) * 1999-12-09 2004-04-27 John E. Stocking Catheter assembly having a fenestrated dilator
US6810872B1 (en) 1999-12-10 2004-11-02 Unisia Jecs Corporation Inhalant medicator
PE20010720A1 (en) 1999-12-11 2001-07-26 Glaxo Group Ltd MEDICATION DISTRIBUTOR
US6302101B1 (en) 1999-12-14 2001-10-16 Daniel Py System and method for application of medicament into the nasal passage
US6679256B2 (en) 1999-12-17 2004-01-20 Nektar Therapeutics Systems and methods for extracting powders from receptacles
IT1317720B1 (en) * 2000-01-07 2003-07-15 Chiesi Farma Spa DEVICE FOR THE ADMINISTRATION OF AEROSOL DOSED PRESSURIZED INPROPELLENT HYDROFLUOROALKANS.
US6651655B1 (en) 2000-01-18 2003-11-25 Quadrant Technologies Limited Inhaled vaccines
US6948491B2 (en) 2001-03-20 2005-09-27 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
SI1163920T1 (en) 2000-06-13 2004-12-31 Andi-Ventis Limited Mouthpiece for a particulate inhaler
TWI224515B (en) 2000-06-23 2004-12-01 Norton Healthcare Ltd Pre-metered dose magazine for breath-actuated dry powder inhaler
AR028747A1 (en) 2000-06-23 2003-05-21 Norton Health Care Ltd DEGREME FOR DRY POWDER INHALER OPERATED BY BREATHING, A DRY POWDER INHALER AND A DRY POWDER DEFAULT METHOD.
WO2002004064A1 (en) * 2000-07-12 2002-01-17 Oma Medical Technologies, Inc. Minimally invasive bypass system and related methods
IT1318765B1 (en) 2000-08-11 2003-09-10 Med 2000 Srl SPRAY SPRAYER FOR AEROSOL THERAPY
US6595210B2 (en) * 2000-11-27 2003-07-22 Unisia Jecs Corporation Inhalator for administering powder composition
US20020124843A1 (en) 2001-02-01 2002-09-12 Skiba Jeffry B. Eye medication delivery system
ZA200306564B (en) 2001-02-26 2004-10-15 Optinose As Nasal devices.
US6550472B2 (en) 2001-03-16 2003-04-22 Aerogen, Inc. Devices and methods for nebulizing fluids using flow directors
DE10131178A1 (en) 2001-06-29 2003-01-16 Boehringer Ingelheim Pharma Nebulizer for applying liquids to the eyes
DE10131174A1 (en) 2001-06-29 2003-01-16 Boehringer Ingelheim Pharma Nebulizer for applying liquids to the surface of the eye or the blindfold tissue
AU2002340083A1 (en) * 2001-09-28 2003-04-07 Kurve Technology, Inc Nasal nebulizer
US6702997B2 (en) 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US6994083B2 (en) 2001-12-21 2006-02-07 Trudell Medical International Nebulizer apparatus and method
US6851626B2 (en) 2002-01-07 2005-02-08 Aerogen, Inc. Methods and devices for nebulizing fluids
US6705316B2 (en) 2002-03-11 2004-03-16 Battelle Pulmonary Therapeutics, Inc. Pulmonary dosing system and method
US8122881B2 (en) 2002-05-09 2012-02-28 Kurve Technology, Inc. Particle dispersion device for nasal delivery
US6883517B2 (en) 2002-09-30 2005-04-26 Asaf Halamish Downdraft nebulizer
EP1673123A2 (en) 2003-09-05 2006-06-28 Kurve Technology, Inc. Integrated nebulizer and particle dispersing chamber for delivery of medicament

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4461425A (en) * 1982-07-13 1984-07-24 Respiratory Care, Inc. Nebulizer system
US4809692A (en) * 1986-01-31 1989-03-07 Trudell Medical Pediatric asthmatic medication inhaler
US5755218A (en) * 1991-03-05 1998-05-26 Aradigm Corporation Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US5577497A (en) * 1991-05-20 1996-11-26 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5203323A (en) * 1991-07-02 1993-04-20 Tritle Paul E Metered dose inhaler spacer device and associated cleaning brush
US5485828A (en) * 1992-04-29 1996-01-23 Hauser; Jean-Luc Portable device for micropulverization generated by ultrasound waves
US5435282A (en) * 1994-05-19 1995-07-25 Habley Medical Technology Corporation Nebulizer
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US6112746A (en) * 1996-07-26 2000-09-05 Resmed Limited Nasal mask and mask cushion therefor
US5855202A (en) * 1997-10-08 1999-01-05 Andrade; Joseph R. Aerosol holding chamber for a metered-dose inhaler
US6202643B1 (en) * 1998-02-23 2001-03-20 Thayer Medical Corporation Collapsible, disposable MDI spacer and method
US6240917B1 (en) * 1999-12-20 2001-06-05 Joseph R. Andrade Aerosol holding chamber for a metered-dose inhaler

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1450885A4 *

Also Published As

Publication number Publication date
EP1450885A2 (en) 2004-09-01
US7866316B2 (en) 2011-01-11
US20130263846A1 (en) 2013-10-10
US20070068514A1 (en) 2007-03-29
EP1450885A4 (en) 2005-03-09
AU2002340083A1 (en) 2003-04-07
US7231919B2 (en) 2007-06-19
JP4795637B2 (en) 2011-10-19
US9572943B2 (en) 2017-02-21
US20110265787A1 (en) 2011-11-03
US8448637B2 (en) 2013-05-28
WO2003026559A2 (en) 2003-04-03
JP5266184B2 (en) 2013-08-21
US20030079742A1 (en) 2003-05-01
EP1450885B1 (en) 2015-04-22
JP2005503868A (en) 2005-02-10
JP2010036049A (en) 2010-02-18

Similar Documents

Publication Publication Date Title
WO2003026559A3 (en) Nasal nebulizer
USD412572S (en) Nasal inhaler adaptor for left and right nostril
USD398992S (en) Nasal inhaler
AU2001247250A1 (en) Nasal oral respiratory interface
AU2001248673A1 (en) Nasal inhaler
WO2003059413A3 (en) Aerosol generator for drug formulation
WO2003022332A3 (en) Adaptors for inhalers to improve performance
AU4503599A (en) Nasal resuscitator mask and resuscitator hose
WO2003082406A3 (en) Nasal mask
AU2001279544A1 (en) Inhalator and pertaining atomizer
AU2003297999A1 (en) Pressure face mask and nasal mask
EP1515774A4 (en) Nasal devices including dilation and user communication and methods of using same
CA2257329A1 (en) Nebulized budesonide for the treatment of respiratory diseases
EP1136093A3 (en) Device for the controlled inhalation of a therapeutical aerosol
AU2001240581A1 (en) Inhalation nebulizer
AU2002316771A1 (en) Guanylate-cyclase c ligand, administered via the airways, for the treatment of respiratory airway problems
USD461897S1 (en) Human body respiratory vest
CA2288747A1 (en) Inhalation device
USD469876S1 (en) Human respiratory bladder
USD518572S1 (en) Laryngeal mask airway device
AU6083899A (en) Combination of c1-inh and lung surfactant for the treatment of respiratory disorders
AU2002247280A1 (en) Ocular drug delivery nebulizer
AU2003263953A1 (en) Nasal irrigation solutions and methods of using same
CA2288010A1 (en) Nasal cannula
USD540940S1 (en) Front face of headgear for respiratory mask

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS JP KE KG KP KR LC LK LR LS LT LU LV MA MD MG MN MW MX MZ NO NZ OM PH PL PT RU SD SE SG SI SK SL TJ TM TN TR TZ UA UG US UZ VC VN YU ZA ZM

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2003530198

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2002778422

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2002778422

Country of ref document: EP