WO2003028563A3 - Skin lesion exciser and skin-closure device therefor - Google Patents

Skin lesion exciser and skin-closure device therefor Download PDF

Info

Publication number
WO2003028563A3
WO2003028563A3 PCT/US2002/031037 US0231037W WO03028563A3 WO 2003028563 A3 WO2003028563 A3 WO 2003028563A3 US 0231037 W US0231037 W US 0231037W WO 03028563 A3 WO03028563 A3 WO 03028563A3
Authority
WO
WIPO (PCT)
Prior art keywords
skin
lesion
blade
excision
engagement portion
Prior art date
Application number
PCT/US2002/031037
Other languages
French (fr)
Other versions
WO2003028563A2 (en
Inventor
Michael Kenneth Banbury
Jillian Elizabeth Banbury
Original Assignee
Cleveland Clinic Foundation
Michael Kenneth Banbury
Jillian Elizabeth Banbury
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to MXPA04002966A priority Critical patent/MXPA04002966A/en
Priority to CA 2460949 priority patent/CA2460949C/en
Priority to BR0212981-7A priority patent/BR0212981A/en
Priority to JP2003531904A priority patent/JP4156514B2/en
Priority to DE60233810T priority patent/DE60233810D1/en
Priority to EP20020763795 priority patent/EP1434529B1/en
Application filed by Cleveland Clinic Foundation, Michael Kenneth Banbury, Jillian Elizabeth Banbury filed Critical Cleveland Clinic Foundation
Priority to AU2002327785A priority patent/AU2002327785B2/en
Priority to IL16095802A priority patent/IL160958A0/en
Priority to AT02763795T priority patent/ATE443480T1/en
Publication of WO2003028563A2 publication Critical patent/WO2003028563A2/en
Publication of WO2003028563A3 publication Critical patent/WO2003028563A3/en
Priority to ZA2004/02461A priority patent/ZA200402461B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3209Incision instruments
    • A61B17/32093Incision instruments for skin incisions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/064Surgical staples, i.e. penetrating the tissue
    • A61B17/0644Surgical staples, i.e. penetrating the tissue penetrating the tissue, deformable to closed position
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/068Surgical staplers, e.g. containing multiple staples or clamps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/30Surgical pincettes without pivotal connections
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3205Excision instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/064Surgical staples, i.e. penetrating the tissue
    • A61B17/0643Surgical staples, i.e. penetrating the tissue with separate closing member, e.g. for interlocking with staple
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/08Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3205Excision instruments
    • A61B17/32053Punch like cutting instruments, e.g. using a cylindrical or oval knife
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3209Incision instruments
    • A61B17/3211Surgical scalpels, knives; Accessories therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B2010/0208Biopsy devices with actuators, e.g. with triggered spring mechanisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00747Dermatology
    • A61B2017/00761Removing layer of skin tissue, e.g. wrinkles, scars or cancerous tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/064Surgical staples, i.e. penetrating the tissue
    • A61B2017/0641Surgical staples, i.e. penetrating the tissue having at least three legs as part of one single body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/08Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A61B2017/081Tissue approximator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/122Clamps or clips, e.g. for the umbilical cord
    • A61B2017/1225Clamps or clips, e.g. for the umbilical cord for clipping and cutting in a single operation

Abstract

A skin lesion exciser including a moving blade, wherein excision of a skin lesion placed in proximity to the blade is effected by movement of the blade against the skin, a moving engagement portion, wherein the blade and the engagement portion have coincident movement, and a skin-closure device having an open condition prior to excision of the skin lesion, and a closed conditions in which the device holds the skin closed after excision of the skin lesion. The device is in engagement with the engagement portion during movement of the blade, and the device is moved from its open to its closed condition in response to movement of the engagement portion. The excision of the skin lesion and the closure of the skin are substantially simultaneous. The present invention also provides a method for excising a skin lesion including: positioning a skin lesion above a moving blade; slicing the lesion from the skin with the blade; and substantially simultaneously with excision of the lesion, closing the skin beneath the moving blade. The present invention also provides a skin-closure device which may be used in conjunction with an inventive exciser.
PCT/US2002/031037 2001-02-15 2002-09-30 Skin lesion exciser and skin-closure device therefor WO2003028563A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
CA 2460949 CA2460949C (en) 2001-10-01 2002-09-30 Skin lesion exciser and skin-closure device therefor
BR0212981-7A BR0212981A (en) 2001-02-15 2002-09-30 Skin lesion excision instrument, method for excising a skin lesion, and skin closure device
JP2003531904A JP4156514B2 (en) 2001-10-01 2002-09-30 Skin lesion remover and skin closure device for the same
DE60233810T DE60233810D1 (en) 2001-10-01 2002-09-30 DEVICE FOR THE EXCISION OF SKIN LUNGSION AND SKIN CLOSURE DEVICE THEREFOR
EP20020763795 EP1434529B1 (en) 2001-10-01 2002-09-30 Skin lesion exciser and skin-closure device therefor
MXPA04002966A MXPA04002966A (en) 2001-10-01 2002-09-30 Skin lesion exciser and skin-closure device therefor.
AU2002327785A AU2002327785B2 (en) 2001-10-01 2002-09-30 Skin lesion exciser and skin-closure device therefor
IL16095802A IL160958A0 (en) 2001-10-01 2002-09-30 Skin lesion exciser and skin-closure device therefor
AT02763795T ATE443480T1 (en) 2001-10-01 2002-09-30 DEVICE FOR EXCISING SKIN LESIONS AND SKIN CLOSURE DEVICE THEREFOR
ZA2004/02461A ZA200402461B (en) 2001-10-01 2004-03-29 Skin lesion exciser and skin-closure device therefor

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US32625401P 2001-10-01 2001-10-01
US60/326,254 2001-10-01
US33227601P 2001-11-14 2001-11-14
US60/332,276 2001-11-14
US35752002P 2002-02-15 2002-02-15
US60/357,520 2002-02-15

Publications (2)

Publication Number Publication Date
WO2003028563A2 WO2003028563A2 (en) 2003-04-10
WO2003028563A3 true WO2003028563A3 (en) 2003-08-07

Family

ID=27406448

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/031037 WO2003028563A2 (en) 2001-02-15 2002-09-30 Skin lesion exciser and skin-closure device therefor

Country Status (11)

Country Link
US (1) US7806907B2 (en)
EP (1) EP1434529B1 (en)
JP (1) JP4156514B2 (en)
AT (1) ATE443480T1 (en)
AU (1) AU2002327785B2 (en)
CA (1) CA2460949C (en)
DE (1) DE60233810D1 (en)
IL (1) IL160958A0 (en)
MX (1) MXPA04002966A (en)
WO (1) WO2003028563A2 (en)
ZA (1) ZA200402461B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4156514B2 (en) 2001-10-01 2008-09-24 ザ クリーブランド クリニック ファウンデーション Skin lesion remover and skin closure device for the same
US7513902B2 (en) * 2001-10-01 2009-04-07 The Cleveland Clinic Foundation Skin lesion exciser and skin-closure device therefor
US7799042B2 (en) 2004-05-13 2010-09-21 The Cleveland Clinic Foundation Skin lesion exciser and skin-closure device therefor
US20090036795A1 (en) * 2005-09-26 2009-02-05 Koninklijke Philips Electronics, N.V. Substance sampling and/or substance delivery via skin
US20070232954A1 (en) * 2006-04-04 2007-10-04 Harris Jeffrey P Automated skin biopsy device
US9974928B2 (en) * 2011-05-10 2018-05-22 Safesharp Technologies Corporation Apparatus for securing a medical clamp to a patient
US8556915B2 (en) * 2011-05-26 2013-10-15 Derm Instruments & Innovations Llc Skin removal instrument
US9993620B2 (en) 2013-06-28 2018-06-12 Safesharp Technologies Corporation Catheter anchoring device and method
US9993230B2 (en) 2014-08-21 2018-06-12 Seton Healthcare Family Shave biopsy devices and related methods
CN105997193B (en) * 2016-07-27 2018-10-09 中国人民解放军第三军医大学第二附属医院 Medical spring forceps
WO2018119480A1 (en) * 2016-12-23 2018-06-28 Cedars-Sinai Medical Center Devices and methods for performing skin biopsies
JP6844842B2 (en) * 2017-03-08 2021-03-17 学校法人 芝浦工業大学 Medical forceps and medical forceps system
CN112137686B (en) * 2020-09-24 2021-09-10 青岛市城阳区人民医院 Scab removing device for burn department
CN114027939B (en) * 2021-11-22 2023-05-23 中国人民解放军空军军医大学 Wart body cutting device for dermatology

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3111996A1 (en) * 1981-03-26 1982-10-14 Lee, George S., 90021 Los Angeles, Calif. Skin clip and device for applying such a clip
EP0092383A2 (en) * 1982-04-15 1983-10-26 Ethicon, Inc. Silicone coated surgical staple
US4467805A (en) * 1982-08-25 1984-08-28 Mamoru Fukuda Skin closure stapling device for surgical procedures
US4610251A (en) * 1985-04-19 1986-09-09 Kumar Sarbjeet S Surgical staple
US4976909A (en) * 1985-05-13 1990-12-11 Ethicon, Inc. Method for manufacture of surgical fastening device
US5209755A (en) * 1992-06-05 1993-05-11 Stella Abrahan Dermal exciser
US5219354A (en) * 1989-07-13 1993-06-15 Choudhury Vijay K Dissecting-cum haemostapling scissors
WO1995034245A1 (en) * 1994-06-10 1995-12-21 University Of Massachusetts Medical Center Safety lock needle

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US363538A (en) 1887-05-24 Suegical
US2156351A (en) * 1938-08-08 1939-05-02 Paul Gertrude Child's feeding bowl
US2994321A (en) 1958-02-26 1961-08-01 Mueller & Company V Punch
US3391690A (en) 1965-04-05 1968-07-09 Armao Thomas Anthony Biopsy instrument including tissue heating or cooling means and method of use
US3373742A (en) 1965-09-02 1968-03-19 United Carr Inc Bandage fastener and assembly
US3353531A (en) 1965-10-22 1967-11-21 Armao Thomas Anthony Biopsy instrument with specimen lifting means
US3323208A (en) * 1965-11-08 1967-06-06 Jr James S Hurley Simultaneous clamping and cutting means
US3520306A (en) 1967-11-08 1970-07-14 Johnson & Johnson Wound closure
SU314382A1 (en) 1970-05-04 1973-08-28 Б. А. Смирнов, В. Л. Рынков, Н. Д. Лукичев , Э. И. Аксенова Всесоюзный научно исследовательский институт хирургической аппаратуры , инструментов
US3857140A (en) 1973-02-28 1974-12-31 Rubricius J Detachable bandage clasp
US4399810A (en) 1979-11-28 1983-08-23 Samuels Peter B Skin clip and applier
US4465071A (en) 1981-10-26 1984-08-14 Samuels Peter B Method of applying skin clips
US4682598A (en) * 1984-08-23 1987-07-28 Dan Beraha Vasectomy instrument
US4651753A (en) 1984-10-12 1987-03-24 Jayco Pharmaceuticals Endoscopic multiple biopsy instrument
US5127915A (en) * 1984-10-29 1992-07-07 Mattson Philip D Surgical instrument for severing and clamping an umbilical cord
US4754756A (en) 1986-12-12 1988-07-05 Shelanski Morris V Dermatome
US4815468A (en) 1987-01-09 1989-03-28 Annand David S Sutureless closure
CA1303934C (en) 1987-11-03 1992-06-23 David T. Green Fascia clip
US4943295A (en) 1988-07-13 1990-07-24 Hartlaub Thaddeus J Surgical cutting tool
DE3941108C1 (en) 1989-12-13 1991-06-27 Richard Wolf Gmbh, 7134 Knittlingen, De
US5213907A (en) 1990-10-09 1993-05-25 Diamond Technologies Company Nickel-cobalt-boron-alloy deposited on a substrate
US5104394A (en) * 1990-11-05 1992-04-14 Knoepfler Dennis J Automatic stapler for laparoscopic procedure with selective cutter and suction irrigator
US5133730A (en) 1991-05-15 1992-07-28 International Technidyne Corporation Disposable-retractable finger stick device
US5190560A (en) 1991-06-20 1993-03-02 Woods John B Instrument for ligation and castration
US5176703A (en) 1991-10-30 1993-01-05 Peterson Meldon L Sutureless closure for a skin wound or incision
CA2088883A1 (en) * 1992-02-13 1993-08-14 David T. Green Endoscopic ligating instrument
US5258012A (en) 1992-06-30 1993-11-02 Ethicon, Inc. Surgical fasteners
US5358510A (en) 1993-01-26 1994-10-25 Ethicon, Inc. Two part surgical fastener
JP2630197B2 (en) 1993-04-28 1997-07-16 株式会社ニッショー Blood suction device
US5624451A (en) 1993-10-18 1997-04-29 American Safety Razor Flexible blade for removing skin lesions
US5423857A (en) 1993-11-02 1995-06-13 Ethicon, Inc. Three piece surgical staple
US5425741A (en) 1993-12-17 1995-06-20 Autogenics Tissue cutting die
US5425740A (en) 1994-05-17 1995-06-20 Hutchinson, Jr.; William B. Endoscopic hernia repair clip and method
US5628759A (en) 1994-09-29 1997-05-13 American Safety Razor Company Flexible surgical razor
US5674234A (en) 1994-09-29 1997-10-07 American Safety Razor Company Flexible surgical razor
US5555892A (en) 1994-11-14 1996-09-17 Tipton; Clyde C. Biopsy shaver
US5620452A (en) * 1994-12-22 1997-04-15 Yoon; Inbae Surgical clip with ductile tissue penetrating members
US6015417A (en) 1996-01-25 2000-01-18 Reynolds, Jr.; Walker Surgical fastener
US5842999A (en) 1996-07-31 1998-12-01 C.R. Bard, Inc. Automated tissue sampling device
US5868763A (en) 1996-09-16 1999-02-09 Guidant Corporation Means and methods for performing an anastomosis
US6811555B1 (en) 1996-09-16 2004-11-02 Origin Medsystems, Inc. Method and apparatus for performing anastomosis with eversion of tissue edges and joining of exposed intima of the everted tissue
US5931847A (en) 1997-01-09 1999-08-03 Ethicon Endo-Surgery, Inc. Surgical cutting instrument with improved cutting edge
US5985217A (en) 1997-07-17 1999-11-16 The Regents Of The University Of California Microfabricated instrument for tissue biopsy and analysis
US6146399A (en) 1997-10-08 2000-11-14 Lee; Scott S. Tissue cutting clamp apparatus
US6106542A (en) * 1998-01-23 2000-08-22 Microsurgical Laboratories, Inc. Surgical forceps
WO2000056227A1 (en) 1999-03-19 2000-09-28 By-Pass, Inc. Advanced closure device
US6126615A (en) 1998-07-10 2000-10-03 Allen; Michael E Sutureless guided skin biopsy system
US6758824B1 (en) 2000-11-06 2004-07-06 Suros Surgical Systems, Inc. Biopsy apparatus
US7211101B2 (en) 2000-12-07 2007-05-01 Abbott Vascular Devices Methods for manufacturing a clip and clip
US6623510B2 (en) 2000-12-07 2003-09-23 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US6719777B2 (en) 2000-12-07 2004-04-13 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
JP4156514B2 (en) 2001-10-01 2008-09-24 ザ クリーブランド クリニック ファウンデーション Skin lesion remover and skin closure device for the same

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3111996A1 (en) * 1981-03-26 1982-10-14 Lee, George S., 90021 Los Angeles, Calif. Skin clip and device for applying such a clip
EP0092383A2 (en) * 1982-04-15 1983-10-26 Ethicon, Inc. Silicone coated surgical staple
US4467805A (en) * 1982-08-25 1984-08-28 Mamoru Fukuda Skin closure stapling device for surgical procedures
US4610251A (en) * 1985-04-19 1986-09-09 Kumar Sarbjeet S Surgical staple
US4976909A (en) * 1985-05-13 1990-12-11 Ethicon, Inc. Method for manufacture of surgical fastening device
US5219354A (en) * 1989-07-13 1993-06-15 Choudhury Vijay K Dissecting-cum haemostapling scissors
US5209755A (en) * 1992-06-05 1993-05-11 Stella Abrahan Dermal exciser
WO1995034245A1 (en) * 1994-06-10 1995-12-21 University Of Massachusetts Medical Center Safety lock needle

Also Published As

Publication number Publication date
AU2002327785B2 (en) 2006-06-01
EP1434529B1 (en) 2009-09-23
EP1434529A2 (en) 2004-07-07
CA2460949C (en) 2008-12-16
JP2005504580A (en) 2005-02-17
ATE443480T1 (en) 2009-10-15
WO2003028563A2 (en) 2003-04-10
US20030078596A1 (en) 2003-04-24
IL160958A0 (en) 2004-08-31
JP4156514B2 (en) 2008-09-24
ZA200402461B (en) 2005-06-29
DE60233810D1 (en) 2009-11-05
CA2460949A1 (en) 2003-04-10
US7806907B2 (en) 2010-10-05
MXPA04002966A (en) 2005-06-20

Similar Documents

Publication Publication Date Title
WO2003028563A3 (en) Skin lesion exciser and skin-closure device therefor
WO2007056318A3 (en) Tissue excision devices and methods
WO2007149232A3 (en) Skin lesion exciser and skin-closure device therefor
WO2006062555A3 (en) Improved surgical rongeur
WO2004093661A3 (en) Methods and devices for cutting tissue
ATE445365T1 (en) DEVICE FOR EXCISING SKIN LESIONS AND SKIN CLOSURE DEVICE THEREFOR
WO2003049783A3 (en) Device and methods for harvesting tissue samples of known geometry
WO2005113374A3 (en) Device, system and method for in-vivo sampling
ATE461668T1 (en) OPERATIONAL INSTRUMENT FOR Clamping, tying and separating tissue
AU2003228769A1 (en) Device and method for ultrasonic tissue excision with tissue selectivity
WO2006017023A3 (en) Biological tissue closure device and method
WO2004026349A3 (en) Surgical fastener particularly for the treatment of gastroesophageal reflux disease (gerd)
WO2007016686A3 (en) Percutaneous tissue excision devices and methods
WO2005109799A3 (en) Follicular extraction method and device
WO2004064621A3 (en) Method and apparatus for less invasive knee resection
AU5160500A (en) Apparatuses, methods and compositions for closing tissue puncture openings
BR9815197A (en) Catheter assembly and processes for overcoming and fracturing a vascular occlusion
WO2004031723A3 (en) Method and apparatus for hemostasis and blood management
WO2007078680A3 (en) Tissue cutting device
WO2005013831A3 (en) Device for transcutaneous biopsy of tissues
WO2001076364A3 (en) Composition and methods for tissue preservation
MXPA03008178A (en) Composition, apparatus and method for skin rejuvenation.
WO2002058543A3 (en) Method and device for marking skin during an ultrasound examination
WO2004112615A3 (en) Temporary hemostatic plug apparatus and method of use
WO2008136271A1 (en) Piercing tool

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS JP KE KG KP KR LC LK LR LS LT LU LV MA MD MG MN MW MX MZ NO NZ OM PH PL PT RU SD SE SG SI SK SL TJ TM TN TR TZ UA UG US UZ VN YU ZA ZM

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2002763795

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2460949

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 160958

Country of ref document: IL

WWE Wipo information: entry into national phase

Ref document number: 2004/02461

Country of ref document: ZA

Ref document number: 200402461

Country of ref document: ZA

Ref document number: 2002327785

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: PA/a/2004/002966

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 2003531904

Country of ref document: JP

WWP Wipo information: published in national office

Ref document number: 2002763795

Country of ref document: EP