WO2003030821A3 - Albumin fusion proteins - Google Patents

Albumin fusion proteins Download PDF

Info

Publication number
WO2003030821A3
WO2003030821A3 PCT/US2002/031794 US0231794W WO03030821A3 WO 2003030821 A3 WO2003030821 A3 WO 2003030821A3 US 0231794 W US0231794 W US 0231794W WO 03030821 A3 WO03030821 A3 WO 03030821A3
Authority
WO
WIPO (PCT)
Prior art keywords
fusion proteins
albumin fusion
nucleic acids
vectors
host cells
Prior art date
Application number
PCT/US2002/031794
Other languages
French (fr)
Other versions
WO2003030821A2 (en
Inventor
Craig A Rosen
William A Haseltine
Original Assignee
Human Genome Sciences Inc
Craig A Rosen
William A Haseltine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc, Craig A Rosen, William A Haseltine filed Critical Human Genome Sciences Inc
Priority to AU2002332041A priority Critical patent/AU2002332041A1/en
Publication of WO2003030821A2 publication Critical patent/WO2003030821A2/en
Publication of WO2003030821A3 publication Critical patent/WO2003030821A3/en
Priority to US10/816,042 priority patent/US20050037022A1/en
Priority to US11/341,748 priority patent/US20060166329A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disordrs or conditions using albumin fusion proteins of the invention.
PCT/US2002/031794 2001-10-05 2002-10-04 Albumin fusion proteins WO2003030821A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2002332041A AU2002332041A1 (en) 2001-10-05 2002-10-04 Albumin fusion proteins
US10/816,042 US20050037022A1 (en) 2001-10-05 2004-04-02 Albumin fusion proteins
US11/341,748 US20060166329A1 (en) 2001-10-05 2006-01-30 Albumin fusion proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32728101P 2001-10-05 2001-10-05
US60/327,281 2001-10-05

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/816,042 Continuation US20050037022A1 (en) 2001-10-05 2004-04-02 Albumin fusion proteins

Publications (2)

Publication Number Publication Date
WO2003030821A2 WO2003030821A2 (en) 2003-04-17
WO2003030821A3 true WO2003030821A3 (en) 2003-12-11

Family

ID=23275906

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/031794 WO2003030821A2 (en) 2001-10-05 2002-10-04 Albumin fusion proteins

Country Status (3)

Country Link
US (2) US20050037022A1 (en)
AU (1) AU2002332041A1 (en)
WO (1) WO2003030821A2 (en)

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DK1463751T3 (en) 2001-12-21 2013-08-26 Human Genome Sciences Inc Albumin Fusion Proteins.
AU2002364587A1 (en) 2001-12-21 2003-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
US7220407B2 (en) 2003-10-27 2007-05-22 Amgen Inc. G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction
AU2004295171A1 (en) * 2003-12-03 2005-06-16 Novozymes Biopharma Dk A/S Interleukin-11 fusion proteins
DK1729795T3 (en) * 2004-02-09 2016-04-11 Human Genome Sciences Inc Albumin fusion proteins
CA2586365A1 (en) 2004-11-05 2006-05-26 Northwestern University Use of scf and g-csf in the treatment of cerebral ischemia and neurological disorders
EP1816201A1 (en) 2006-02-06 2007-08-08 CSL Behring GmbH Modified coagulation factor VIIa with extended half-life
JP5061194B2 (en) * 2006-10-27 2012-10-31 イノヴァ ダイアグノスティクス インコーポレイテッド Methods and assays for detecting GP73-specific autoantibodies
US9272034B2 (en) * 2007-10-04 2016-03-01 The Regents Of The University Of California Treatment of conditions related to shock
EP2344913B1 (en) * 2008-10-02 2015-02-18 Ramot at Tel-Aviv University Ltd. Method and system for emitting light
US9295715B2 (en) 2010-10-02 2016-03-29 The Regents Of The University Of California Minimizing intestinal dysfunction
WO2013106485A2 (en) 2012-01-09 2013-07-18 The Scripps Research Institute Ultralong complementarity determining regions and uses thereof
JP2015509091A (en) 2012-01-09 2015-03-26 ザ スクリプス リサーチ インスティテュート Humanized antibody
WO2014110368A1 (en) * 2013-01-11 2014-07-17 The California Institute For Biomedical Research Bovine fusion antibodies
WO2015010100A2 (en) 2013-07-18 2015-01-22 Fabrus, Inc. Humanized antibodies with ultralong complementarity determining regions
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
CA3100007A1 (en) 2018-05-14 2019-11-21 Werewolf Therapeutics, Inc. Activatable interleukin-2 polypeptides and methods of use thereof
SG11202011309SA (en) 2018-05-14 2020-12-30 Werewolf Therapeutics Inc Activatable interleukin 12 polypeptides and methods of use thereof
CN111418580A (en) * 2020-05-25 2020-07-17 山东万能干细胞生物技术有限公司 Stem cell cryopreservation solution and cryopreservation method

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Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216131A (en) * 1989-02-23 1993-06-01 Genentech, Inc. Lymphocyte homing receptors
US6210901B1 (en) * 1994-01-31 2001-04-03 Roche Diagnostics Gmbh Specific binding substances for antibodies and their use for immunoassays or vaccines
US6121231A (en) * 1996-12-06 2000-09-19 Institut Pasteur Use of the KAL protein and treatment with the KAL protein in treatment of retinal, renal, neuromal and neural injury
US6548653B1 (en) * 1998-06-15 2003-04-15 Genzyme Transgenics Corporation Erythropoietin analog-human serum albumin fusion
US20010056075A1 (en) * 1999-07-19 2001-12-27 Jeno Gyuris Chimeric polypeptides of serum albumin and uses related thereto

Also Published As

Publication number Publication date
US20060166329A1 (en) 2006-07-27
US20050037022A1 (en) 2005-02-17
WO2003030821A2 (en) 2003-04-17
AU2002332041A1 (en) 2003-04-22

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