WO2003033057A1 - Injection device comprising an energy accumulator - Google Patents

Injection device comprising an energy accumulator Download PDF

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Publication number
WO2003033057A1
WO2003033057A1 PCT/CH2002/000563 CH0200563W WO03033057A1 WO 2003033057 A1 WO2003033057 A1 WO 2003033057A1 CH 0200563 W CH0200563 W CH 0200563W WO 03033057 A1 WO03033057 A1 WO 03033057A1
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WO
WIPO (PCT)
Prior art keywords
capacitor
injection device
injection
energy
capacitors
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PCT/CH2002/000563
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German (de)
French (fr)
Inventor
Edgar Hommann
Beat Steffen
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Tecpharma Licensing Ag
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Publication date
Application filed by Tecpharma Licensing Ag filed Critical Tecpharma Licensing Ag
Priority to JP2003535855A priority Critical patent/JP2005505387A/en
Priority to EP02764482A priority patent/EP1438094A1/en
Priority to AU2002328764A priority patent/AU2002328764B2/en
Publication of WO2003033057A1 publication Critical patent/WO2003033057A1/en
Priority to US10/825,865 priority patent/US20050038388A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically

Definitions

  • the invention relates to an injection device with an energy store.
  • Injection devices - often also referred to as pens - or infusion devices are preferably equipped with non-exchangeable batteries or accumulators in order to provide the energy required for an injection. It can be with an injection device such. B. with a needle or needle-free a substance to be injected z. B. introduced through the skin into a body. Injection devices are often about the size of a writing instrument and can be easily transported and operated with one hand.
  • Injection devices are generally said to be small and relatively light. Batteries or accumulators, however, take up a relatively large amount of space in the injection device. A further miniaturization of accumulators leads to a deterioration in the charging behavior, in particular smaller batteries have to be charged over a longer period of time, sometimes several hours, than large batteries in order to be able to provide a larger amount of energy, as is known, for example, in cell phones. A relatively large amount of energy is required to carry out an injection. If a smaller accumulator were used, it would have to be charged over a longer period if several injections were to be carried out. Long loading processes and thus preparation times before performing an injection lead to acceptance problems for the users of such an injection device. Alternative methods for energy storage, such as by means of compressed gas, are relatively complex with regard to the devices required for this and can therefore not be miniaturized in a suitable manner.
  • a capacitor which preferably has a relatively high capacitance.
  • Capacitors are relatively small and do not require complex electronics for charging.
  • capacitors with high currents can be used within a relatively short time, e.g. can be charged quickly in a few seconds without affecting the service life, as is the case with accumulators.
  • capacitors In contrast to the aging of accumulators with multiple charging processes, also known as the memory effect, capacitors have a constant quality even with many charging and discharging processes. In this way, injection devices with a longer service life can be created.
  • the capacitor is advantageously designed to store a sufficient amount of charge or energy to enable an electrical device to perform an injection, such as an injection.
  • B. a magnet or electric motor with a sufficient energy for at least one injection. So it can be stored an amount of energy, which, for. B. is sufficient to accelerate a necessary for injection accelerating element or z. B. to tension a spring provided by z. B. the spring with an electric motor is compressed using the discharge current from the capacitor.
  • the capacitor should be able to store so much energy that with this amount of energy a substance to be injected is dispensed by the injection device and into a body, for. B. can be introduced with a needle or needle-free.
  • a gold capacitor is particularly preferably used as the energy store of the injection device.
  • Gold capacitors can be manufactured with a high capacitance, for example in the range from 1.0 to 10 F, so that when using such gold capacitors it is possible to store a sufficiently large amount of energy in the injection device in a relatively short time using a high charging current.
  • Such gold capacitors are e.g. available from Panasonic as double layer capacitors. Capacitors with high capacitance can also emit high currents, so that energy-intensive processes such as an injection.
  • Electrolytic capacitors or tantalum capacitors can be used to store electrical energy in an injection device, as long as they can provide a sufficiently high capacity. If necessary, several capacitors of the same or different types can be connected in parallel in order to further increase the capacitance provided.
  • a charge status display is preferably provided, with which the charge status of the capacitor or the capacitors can be indicated.
  • the amount of energy stored in the capacitor can be specified relatively precisely by simply measuring the voltage applied to the capacitor, the measurement being able to be carried out essentially without a significant measuring current.
  • battery charge indicators which show an almost fully charged state over a wide operating range of a battery and towards the end indicate a relatively rapidly decreasing charge level
  • a precise indication can be given of how much energy is still available, ie for example how many injections can still be carried out.
  • a circuit or computing device can advantageously be provided which, depending on certain parameters relevant to the injection, such as the discharge quantity, the frictional forces of the ampoule, the viscosity of the substance to be dispensed, the needle length, the needle diameter or other parameters, for how many injection processes the electrical energy stored in the capacitor is still sufficient.
  • the number of injections that can still be carried out is given, e.g. on an LCD or LED display or by means of a number of LEDs lying next to one another, the number of illuminated LEDs, for example, indicating the number of injection processes that can still be carried out after activation of the display.
  • the capacitor can also be used to power the LCD or LED elements.
  • a threshold value detector is advantageously provided which, when the voltage falls below a predetermined minimum, outputs a signal that the amount of energy available has fallen below a predetermined value and e.g. no longer sufficient for an injection.
  • the minimum voltage is advantageously determined such that at least one injection process can still be carried out safely with a capacitor in which a voltage is present above the minimum voltage.
  • a voltage regulator in particular a DC / DC converter, is preferably connected to the capacitor in such a way that an essentially constant DC voltage for operating the injection device, for example an electric motor, can be obtained from the variable DC voltage applied to the capacitor.
  • Buck converters and boost converters are known, with which a DC voltage below or can be obtained above the applied input voltage.
  • a buck-boost converter or inverting switching regulator can also be used.
  • the at least one capacitor used is preferably connected in such a way that it can be charged from an external energy source by inductive coupling.
  • the capacitor in series with a diode, preferably a power diode, and an induction coil to be interconnected, so that the capacitor always with a desired polarity loaded.
  • the capacitor can also be charged through contacts.
  • a capacitor with a large capacitance can advantageously also be used for data storage for a relatively long time or also for a signal output device, such as, for example, provide an optical or acoustic display.

Abstract

The invention relates to an injection device comprising a capacitor as an energy accumulator for the injection.

Description

Injektionsgerät mit Energiespeicher Injection device with energy storage
Die Erfindung bezieht sich auf ein Injektionsgerät mit einem Energiespeicher.The invention relates to an injection device with an energy store.
Injektionsgeräte - häufig auch als Pens bezeichnet - oder Infusionsgeräte werden bevorzugt mit nicht auswechselbaren Batterien oder Akkumulatoren ausgestattet, um die für eine Injektion erforderliche Energie bereitzustellen. Dabei kann mit einem Injektionsgerät z. B. mit einer Nadel oder auch nadelfrei eine zu injizierende Substanz z. B. durch die Haut in einen Körper eingebracht werden. Injektionsgeräte sind häufig etwa so groß wie ein Schreibgerät und können einfach transportiert und mit einer Hand bedient werden.Injection devices - often also referred to as pens - or infusion devices are preferably equipped with non-exchangeable batteries or accumulators in order to provide the energy required for an injection. It can be with an injection device such. B. with a needle or needle-free a substance to be injected z. B. introduced through the skin into a body. Injection devices are often about the size of a writing instrument and can be easily transported and operated with one hand.
Aus der DE 100 04 314 A der Anmelderin ist eine induktive Ladevorrichtung für Injektionsgeräte bekannt.From DE 100 04 314 A by the applicant, an inductive charging device for injection devices is known.
Injektionsgeräte sollen im Allgemeinen klein und relativ leicht sein. Batterien bzw. Akkumulatoren beanspruchen jedoch relativ viel Raum im Injektionsgerät. Eine weitere Miniaturisierung von Akkumulatoren führt zu einer Verschlechterung des Ladeverhaltens, insbesondere müssen kleinere Batterien über einen längeren Zeitraum von zum Teil mehreren Stunden aufgeladen werden als große Batterien, um eine größere Energiemenge zur Verfügung stellen zu können, wie dies z.B. bei Handys bekannt ist. Zum Durchführen einer Injektion wird eine relativ große Energiemenge benötigt. Würde also ein kleinerer Akkumulator verwendet werden, so müsste dieser über einen längeren Zeitraum aufgeladen werden, wenn mehrere Injektionen durchgeführt werden sollen. Lange Ladevorgänge und damit Vorbereitungszeiten vor dem Durchführen einer Injektion führen jedoch zu Akzeptanzproblemen bei den Benutzern einer solchen Injektionsvorrichtung. Alternative Verfahren zur Energiespeicherung, wie z.B. mittels Druckgas, sind relativ aufwendig hinsichtlich der hierfür erforderlichen Vorrichtungen und können somit auch nicht geeignet miniaturisiert werden.Injection devices are generally said to be small and relatively light. Batteries or accumulators, however, take up a relatively large amount of space in the injection device. A further miniaturization of accumulators leads to a deterioration in the charging behavior, in particular smaller batteries have to be charged over a longer period of time, sometimes several hours, than large batteries in order to be able to provide a larger amount of energy, as is known, for example, in cell phones. A relatively large amount of energy is required to carry out an injection. If a smaller accumulator were used, it would have to be charged over a longer period if several injections were to be carried out. Long loading processes and thus preparation times before performing an injection lead to acceptance problems for the users of such an injection device. Alternative methods for energy storage, such as by means of compressed gas, are relatively complex with regard to the devices required for this and can therefore not be miniaturized in a suitable manner.
Es ist eine Aufgabe der vorliegenden Erfindung ein Injektionsgerät vorzuschlagen, welches eine ausreichende Energiemenge speichern und vergleichsweise schnell geladen werden kann.It is an object of the present invention to propose an injection device which can store a sufficient amount of energy and can be charged comparatively quickly.
Diese Aufgabe wird durch ein Injektionsgerät nach Anspruch 1 gelöst. Vorteilhafte Ausführungsformen ergeben sich aus den Unteransprüchen.This object is achieved by an injection device according to claim 1. Advantageous embodiments result from the subclaims.
Erfindungsgemäß ist in einem Injektionsgerät oder auch einem Infusionsgerät, welches z.B. eine Nadel aufweisen kann oder auch nadelfrei ausgebildet sein kann, ein Kondensator vorgesehen, welcher bevorzugt eine relativ hohe Kapazität aufweist. Kondensatoren sind relativ klein und benötigen keine aufwendige Elektronik zum Aufladen. Im Gegensatz zu Akkumulatoren können Kondensatoren mit hohen Strömen innerhalb relativ kurzer Zeit, z.B. wenigen Sekunden schnell geladen werden, ohne dass hierdurch die Lebensdauer beeinträchtigt wird, wie dies bei Akkumulatoren der Fall ist. Im Gegensatz zur Alterung von Akkumulatoren bei mehreren Ladevorgängen, auch als Memory-Effekt bezeichnet, haben Kondensatoren auch bei vielen Lade- und Entladevorgängen eine gleichbleibende Qualität. Hierdurch können Injektionsvorrichtungen mit längerer Lebensdauer geschaffen werden.According to the invention in an injection device or an infusion device, which e.g. can have a needle or can also be formed without a needle, a capacitor is provided which preferably has a relatively high capacitance. Capacitors are relatively small and do not require complex electronics for charging. In contrast to accumulators, capacitors with high currents can be used within a relatively short time, e.g. can be charged quickly in a few seconds without affecting the service life, as is the case with accumulators. In contrast to the aging of accumulators with multiple charging processes, also known as the memory effect, capacitors have a constant quality even with many charging and discharging processes. In this way, injection devices with a longer service life can be created.
Der Kondensator ist vorteilhaft so ausgelegt, dass er eine ausreichende Menge einer Ladung oder Energie speichern kann, um eine elektrische Vorrichtung zur Durchführung einer Injektion, wie z. B. einen Magneten oder Elektromotor, mit einer für mindestens eine Injektion ausreichenden Energie zu versorgen. Es kann also eine Energiemenge gespeichert werden, welche z. B. ausreichend ist, um ein zur Injektion erforderliches Beschleunigungselement ausreichend zu beschleunigen oder um z. B. eine hierzu vorgesehene Feder zu spannen, indem z. B. die Feder mit einem Elektromotor unter Verwendung des Entladestromes vom Kondensator komprimiert wird. Allgemein soll der Kondensator so viel Energie speichern können, dass mit dieser Energiemenge eine zu injizierende Substanz durch das Injektionsgerät ausgegeben und in einen Körper z. B. mit einer Nadel oder nadelfrei eingebracht werden kann.The capacitor is advantageously designed to store a sufficient amount of charge or energy to enable an electrical device to perform an injection, such as an injection. B. a magnet or electric motor with a sufficient energy for at least one injection. So it can be stored an amount of energy, which, for. B. is sufficient to accelerate a necessary for injection accelerating element or z. B. to tension a spring provided by z. B. the spring with an electric motor is compressed using the discharge current from the capacitor. In general, the capacitor should be able to store so much energy that with this amount of energy a substance to be injected is dispensed by the injection device and into a body, for. B. can be introduced with a needle or needle-free.
Besonders bevorzugt wird ein Goldkondensator als Energiespeicher des Injektionsgerätes verwendet. Goldkondensatoren können mit einer hohen Kapazität beispielsweise im Bereich von 1 ,0 bis 10 F hergestellt werden, so dass es bei Verwendung solcher Goldkondensatoren möglich ist über einen hohen Ladestrom innerhalb relativ kurzer Zeit eine ausreichend große Energiemenge in dem Injektionsgerät zu speichern. Solche Goldkondensatoren sind z.B. von der Firma Panasonic als Doppelschicht-Kondensatoren erhältlich. Kondensatoren mit hoher Kapazität können auch hohe Ströme abgeben, so dass energieintensive Vorgänge, wie z.B. eine Injektion, durchgeführt werden können.A gold capacitor is particularly preferably used as the energy store of the injection device. Gold capacitors can be manufactured with a high capacitance, for example in the range from 1.0 to 10 F, so that when using such gold capacitors it is possible to store a sufficiently large amount of energy in the injection device in a relatively short time using a high charging current. Such gold capacitors are e.g. available from Panasonic as double layer capacitors. Capacitors with high capacitance can also emit high currents, so that energy-intensive processes such as an injection.
Vorteilhaft können auch andere Kondensatoren, wie z.B. Elektrolytkondensatoren oder Tantal-Kondensatoren zur Speicherung von elektrischer Energie in einem Injektionsgerät verwendet werden, solange mit diesen eine ausreichend hohe Kapazität bereitgestellt werden kann. Gegebenenfalls können mehrere Kondensatoren gleicher oder verschiedener Bauart parallel geschaltet werden, um die bereitgestellte Kapazität weiter zu erhöhen.Other capacitors, such as e.g. Electrolytic capacitors or tantalum capacitors can be used to store electrical energy in an injection device, as long as they can provide a sufficiently high capacity. If necessary, several capacitors of the same or different types can be connected in parallel in order to further increase the capacitance provided.
Bevorzugt ist eine Ladestandsanzeige vorgesehen, mit welcher der Ladezustand des Kondensators oder der Kondensatoren angegeben werden kann. Bei der erfindungsgemäßen Verwendung eines Kondensators hoher Kapazität als einzigem Energiespeicher kann relativ genau die Menge der im Kondensator gespeicherten Energie angegeben werden, indem einfach die am Kondensator anliegende Spannung gemessen wird, wobei die Messung im Wesentlich ohne einen nennenswerten Messstrom vorgenommen werden kann. Im Gegensatz zu Ladestandsanzeigen bei Akkumulatoren, die über einen weiten Betriebsbereich eines Akkumulators einen fast vollständig geladenen Zustand anzeigen und gegen Ende einen relativ schnell abfallenden Ladestand anzeigen, kann erfindungsgemäß eine präzise Angabe erfolgen wie viel Energie noch zur Verfügung steht, d. h. z.B. wie viel Injektionen noch durchgeführt werden können.A charge status display is preferably provided, with which the charge status of the capacitor or the capacitors can be indicated. When using a capacitor with high capacitance as the only energy store according to the invention, the amount of energy stored in the capacitor can be specified relatively precisely by simply measuring the voltage applied to the capacitor, the measurement being able to be carried out essentially without a significant measuring current. In contrast to battery charge indicators, which show an almost fully charged state over a wide operating range of a battery and towards the end indicate a relatively rapidly decreasing charge level, according to the invention a precise indication can be given of how much energy is still available, ie for example how many injections can still be carried out.
Hierzu kann vorteilhaft eine Schaltung oder Rechenvorrichtung vorgesehen sein, welche in Abhängigkeit von bestimmten für die Injektion relevanten Parametern, wie z.B. der Ausschüttmenge, den Reibungskräften der Ampulle, der Viskosität der abzugebenden Substanz, der Nadellänge, des Nadeldurchmessers oder anderen Parametern ermitteln kann, für wie viele Injektionsvorgänge die im Kondensator gespeicherte elektrische Energie noch ausreicht.For this purpose, a circuit or computing device can advantageously be provided which, depending on certain parameters relevant to the injection, such as the discharge quantity, the frictional forces of the ampoule, the viscosity of the substance to be dispensed, the needle length, the needle diameter or other parameters, for how many injection processes the electrical energy stored in the capacitor is still sufficient.
Dabei ist es vorteilhaft, wenn die Anzahl der noch ausführbaren Injektionen angegeben wird, z.B. auf einer LCD oder LED-Anzeige oder mittels einer Anzahl von nebeneinaderliegenden LEDs, wobei nach Aktivierung der Anzeige beispielsweise die Anzahl der leuchtenden LEDs die Anzahl der noch durchführbaren Injektionsvorgänge angibt. Der Kondensator kann auch zur Stromversorgung der LCD- oder LED-Elemente verwendet werden.It is advantageous if the number of injections that can still be carried out is given, e.g. on an LCD or LED display or by means of a number of LEDs lying next to one another, the number of illuminated LEDs, for example, indicating the number of injection processes that can still be carried out after activation of the display. The capacitor can also be used to power the LCD or LED elements.
Vorteilhaft ist ein Schwellwertdetektor vorgesehen, welcher bei Unterschreiten einer vorgegebenen Mindestspannung ein Signal ausgibt, dass die zur Verfügung stehende Energiemenge einen vorgegebenen Wert unterschritten hat und z.B. für eine Injektion nicht mehr ausreicht. Dabei wird die Mindestspannung vorteilhaft so festgelegt, dass mit einem Kondensator, bei dem eine Spannung oberhalb der Mindestspannung anliegt, noch mindestens ein Injektionsvorgang sicher durchgeführt werden kann.A threshold value detector is advantageously provided which, when the voltage falls below a predetermined minimum, outputs a signal that the amount of energy available has fallen below a predetermined value and e.g. no longer sufficient for an injection. In this case, the minimum voltage is advantageously determined such that at least one injection process can still be carried out safely with a capacitor in which a voltage is present above the minimum voltage.
Bevorzugt ist ein Spannungsregler, insbesondere ein DC/DC-Konverter so mit dem Kondensator verschaltet, dass aus der variablen am Kondensator anliegenden Gleichspannung eine im wesentlichen konstante Gleichspannung zum Betrieb des Injektionsgerätes, z.B. eines Elektromotors, erhalten werden kann. Es sind Buck- Konverter und Boost-Konverter bekannt, mit welchen eine Gleichspannung unterhalb oder oberhalb der anliegenden Eingangspannung erhalten werden kann. Ebenso kann ein Buck-Boost-Konverter oder invertierender Schaltregler verwendet werden.A voltage regulator, in particular a DC / DC converter, is preferably connected to the capacitor in such a way that an essentially constant DC voltage for operating the injection device, for example an electric motor, can be obtained from the variable DC voltage applied to the capacitor. Buck converters and boost converters are known, with which a DC voltage below or can be obtained above the applied input voltage. A buck-boost converter or inverting switching regulator can also be used.
Bevorzugt ist der verwendete mindestens eine Kondensator so verschaltet, dass er von einer externen Energiequelle aus durch induktive Kopplung geladen werden kann. Diesbezüglich wird auf die Lehre der DE 100 04 314 A verwiesen, die bezüglich der Ausgestaltung einer Ladevorrichtung, der Kopplung eines Gerätes mit einer Ladevorrichtung und der Ausgestaltung der Elektronik in der aufzuladenden Vorrichtung in die vorliegende Beschreibung aufgenommen wird. Insbesondere ist(es vorteilhaft den Kondensator in Reihe mit einer Diode, bevorzugt einer Leistungsdiode und einer Induktionsspule zu verschalten, so dass der Kondensator immer mit einer gewünschten Polung geladen wird. Jedoch kann der Kondensator auch über Kontakte geladen werden.The at least one capacitor used is preferably connected in such a way that it can be charged from an external energy source by inductive coupling. In this regard, reference is made to the teaching of DE 100 04 314 A, which is included in the present description with regard to the design of a charging device, the coupling of a device to a charging device and the design of the electronics in the device to be charged. In particular is (it advantageous to the capacitor in series with a diode, preferably a power diode, and an induction coil to be interconnected, so that the capacitor always with a desired polarity loaded. However, the capacitor can also be charged through contacts.
Vorteilhaft kann ein Kondensator großer Kapazität außer zur Durchführung einer Injektion Energie auch für eine Datenspeicherung auf relativ lange Zeit oder auch für eine Signalausgabevorrichtung, wie z.B. eine optische oder akustische Anzeige zur Verfügung stellen. In addition to carrying out an injection of energy, a capacitor with a large capacitance can advantageously also be used for data storage for a relatively long time or also for a signal output device, such as, for example, provide an optical or acoustic display.

Claims

Injektionsgerät mit EnergiespeicherPatentansprüche Injection device with energy storage
1. Injektionsgerät mit einem Kondensator als Energiespeicher für die Durchführung mindestens einer Injektion.1. Injection device with a capacitor as an energy store for carrying out at least one injection.
2. Injektionsgerät nach Anspruch 1 , wobei der Kondensator ein Goldkondensator, insbesondere ein Doppelschicht-Kondensator ist.2. Injection device according to claim 1, wherein the capacitor is a gold capacitor, in particular a double-layer capacitor.
3. Injektionsgerät nach Anspruch 1 und 2, wobei eine Ladestandsanzeige, insbesondere ein Spannungsmessgerät mit dem Kondensator verbunden ist.3. Injection device according to claim 1 and 2, wherein a charge level indicator, in particular a voltage measuring device is connected to the capacitor.
4. Injektionsgerät nach einem der vorhergehenden Ansprüche, wobei ein Rechner zur Bestimmung der Anzahl der noch durchführbaren Injektionsvorgänge vorgesehen ist.4. Injection device according to one of the preceding claims, wherein a computer is provided for determining the number of injection processes that can still be carried out.
5. Injektionsgerät nach einem der vorhergehenden Ansprüche, wobei ein Schwellwertdetektor mit dem mindestens einen Kondensator verbunden ist, um eine vorgegebene Mindestspannung zu detektieren, welche bevorzugt charakteristisch für eine Energiemenge ist, mit welcher mindestens eine Injektion durchgeführt werden kann. 5. Injection device according to one of the preceding claims, wherein a threshold value detector is connected to the at least one capacitor in order to detect a predetermined minimum voltage, which is preferably characteristic of an amount of energy with which at least one injection can be carried out.
6. Injektionsgerät nach einem der vorhergehenden Ansprüche, wobei ein DC/DC- Konverter mit dem Kondensator verbunden ist.6. Injection device according to one of the preceding claims, wherein a DC / DC converter is connected to the capacitor.
7. Injektionsgerät nach einem der vorhergehenden Ansprüche, wobei der Kondensator über eine induktive Kopplung aufgeladen werden kann.7. Injection device according to one of the preceding claims, wherein the capacitor can be charged via an inductive coupling.
8. Injektionsgerät nach einem der vorhergehenden Ansprüche, wobei eine Signalausgabevorrichtung und/oder ein Speicher vorgesehen ist, welche von dem Kondensator mit Strom versorgt werden. 8. Injection device according to one of the preceding claims, wherein a signal output device and / or a memory is provided which are supplied with current by the capacitor.
PCT/CH2002/000563 2001-10-18 2002-10-15 Injection device comprising an energy accumulator WO2003033057A1 (en)

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JP2003535855A JP2005505387A (en) 2001-10-18 2002-10-15 Injection device with energy storage device
EP02764482A EP1438094A1 (en) 2001-10-18 2002-10-15 Injection device comprising an energy accumulator
AU2002328764A AU2002328764B2 (en) 2001-10-18 2002-10-15 Injection device comprising an energy accumulator
US10/825,865 US20050038388A1 (en) 2001-10-18 2004-04-16 Injection device comprising an energy storage device

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DE10151471.9 2001-10-18
DE10151471A DE10151471A1 (en) 2001-10-18 2001-10-18 Injection device with energy storage

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JP2005505387A (en) 2005-02-24
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AU2002328764B2 (en) 2007-06-28
CN1571684A (en) 2005-01-26

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