WO2003039407A2 - Method for manufacturing a stent - Google Patents
Method for manufacturing a stent Download PDFInfo
- Publication number
- WO2003039407A2 WO2003039407A2 PCT/GB2002/005076 GB0205076W WO03039407A2 WO 2003039407 A2 WO2003039407 A2 WO 2003039407A2 GB 0205076 W GB0205076 W GB 0205076W WO 03039407 A2 WO03039407 A2 WO 03039407A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- stent
- powder
- manufacturing
- laser
- set forth
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C10/00—Solid state diffusion of only metal elements or silicon into metallic material surfaces
- C23C10/28—Solid state diffusion of only metal elements or silicon into metallic material surfaces using solids, e.g. powders, pastes
- C23C10/30—Solid state diffusion of only metal elements or silicon into metallic material surfaces using solids, e.g. powders, pastes using a layer of powder or paste on the surface
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C24/00—Coating starting from inorganic powder
- C23C24/02—Coating starting from inorganic powder by application of pressure only
- C23C24/04—Impact or kinetic deposition of particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/91525—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
- A61F2002/91541—Adjacent bands are arranged out of phase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/9155—Adjacent bands being connected to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/9155—Adjacent bands being connected to each other
- A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
Definitions
- the present invention relates generally to a manufacturing process for stents and stents formed by the manufacturing process, and in particular to methods and stents formed therefrom having increased radiopacity.
- a stent is a medical device, usually a hollow tubular structure, which is inserted into a body lumen to provide support thereto.
- Stents are well known in the art and there are many different types of stents available. Some are configured to be expanded after being located at a desired position in the lumen by an expansive force provided by an inflatable balloon. Others are delivered under compression so that, upon delivery they expand to provide the necessary supporting force. Others are made from heat-sensitive materials that expand at body temperature to provide the necessary supportive force. In recent times there has been a desire to form such stents from smaller and smaller quantities of material to provide greater flexibility, i.e., so that they are more flexible prior to delivery.
- the present invention seeks to provide a method, and a stent produced therefrom, which increases the radiopacity of the stent without causing some of the problems associated with previous attempts at increasing radiopacity.
- a method of manufacturing a stent 0 formed from a metal or metal alloy including the steps of applying a powder of a material having a higher radiopacity than that of the material from which the stent is formed to a region of the surface of the stent, and applying laser light to the surface having the radiopaque powder placed thereon such that the surface melts to incorporate the powder.
- the preferred embodiment of the method may include the step of forming the 5 stent from stainless steel.
- the powder may be formed from gold, platinum, tantalum, niobium, titanium or tungsten or a combination thereof.
- the powder may be applied at the same time as applying the laser light.
- the powder may also be applied by cold gas dynamic spraying.
- the laser light may be generated by a YAG laser, a CO 2 laser, a Diode laser or Femto 0 laser.
- the method may also include the step of cutting holes in the stent using the same laser either before or after fixing the powder to the surface of the stent.
- the laser light may be applied to the powder at least twice in order to smooth the surface profile of the end product.
- the present invention also may be used to manufacture a stent formed from a metal or
- the stent having a powder impregnated in the surface thereof and the power being formed from a material having a radiopacity greater than that of the metal or metal alloy.
- the stent of the present invention manufactured by applying a powder of a material having a higher radiopacity than that of the material from which the stent is formed to a region of the surface of the stent and applying laser light to the surface having the radiopaque powder
- the powder is selected from the group including gold, platinum, tantalum, niobium, titanium or tungsten or a combination thereof.
- Figure 1 is a side view of a known stent
- Figure 2 is a side view of a stent manufactured in accordance with the present invention
- FIGS 3A and 3B are schematic diagrams of the steps of the method of the present invention.
- Figures 4A-4C are a series of images of the surface of stents produced in accordance with the method of the present invention.
- a known stent 1 is shown.
- the stent 1 has a body portion formed from a hollow tube of metal or metal alloy, usually stainless steel, as is well known in the art with cuts or openings in the surface of the stent 1 in a series of holes 2 which define struts 3.
- the stent shown is a balloon-expandable stent 1 and the struts 3 are shaped so that, when a balloon 5 is inserted into the stent 1 and expanded, the stent 1 expands to form a rigid structure that can support a body lumen.
- FIG. 2 shows a stent 1 according to the present invention in which components that correspond to those in the known stent 1 of figure 1 are numbered identically.
- the stent 1 according to the invention has regions 4 of higher radiopacity 4 bonded on struts 3 at either end of the structure of the stent 1. These regions 4 of higher radiopacity enhance the visibility of the stent 1 under x-ray imaging so that, either during deployment or after deployment, a surgeon can more easily view the location of the stent 1.
- Figure 3 A illustrates a preferred embodiment of the method of the present invention at various stages in the process of manufacturing the stent 1 of Figure 2.
- a hollow tube of metal such as stainless steel, is provided with holes 2 etched or cut therein with a laser 6 which may be a YAG laser or, more cost effectively, a CO 2 laser.
- Powdered radiopaque material is then applied either manually or automatically to at least a portion of the struts 3 at either end of the stent 1.
- Laser light either from a separate laser light source or the same laser light source 6 that carried out the etching, is then applied so as to either melt the powder, or the surface of the struts 3, or both, when the light is applied in order to impregnate the surface of the stent 1 with the powder to form a radiopaque region 4.
- the process is repeated in order to provide sufficient number of radiopaque regions 4 to ensure good visibility of the stent 1 in use.
- the laser 6 may be applied a second time in order to smooth the overall surface.
- Figure 3B illustrated another embodiment of the method of the present invention.
- the powder is applied simultaneously with the laser light application.
- This may involve use of a laser light source 6 with a surrounding powder dispensing nozzle 7 or a separate nozzle 7, both of which are shown in the figure.
- the speed of the particles of the powder will preferably be in the range of 0.1 to 20m per second, providing flow rate for the powder particles which will be in the region of 1 to 1000 ⁇ g per second.
- the powder is fed with an inert gas such as argon, helium or nitrogen.
- the laser may be applied a second time, during which powder is not fed to the surface of the stent.
- the method may employ one of a number of types of lasers, and in general it would be expected that the power of the laser would be no more than 50 Watts.
- the method of the invention may be employed using a YAG welding laser with a Nb-Ti alloy powder, and Figure 4A shows a radiopaque region formed by such an approach.
- a 250 am wide line of radiopaque region is formed which rises about 15 to 20 ⁇ m from of the surface of the stent 1.
- the laser light was applied as spots which overlapped, and a higher repetition of the spots can increase the smoothness of the applied radiopaque region as can be seen from Figure 4B.
- Figure 4C shows how the radiopaque region of Figure 4B can be further smoothed by passing the laser light over the region for a second time.
Abstract
Description
Claims
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002339126A AU2002339126A1 (en) | 2001-11-09 | 2002-11-11 | Method for manufacturing a stent |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0127033.9A GB0127033D0 (en) | 2001-11-09 | 2001-11-09 | Stent manufacture |
GB0127033.9 | 2001-11-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003039407A2 true WO2003039407A2 (en) | 2003-05-15 |
WO2003039407A3 WO2003039407A3 (en) | 2003-11-27 |
Family
ID=9925543
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2002/005076 WO2003039407A2 (en) | 2001-11-09 | 2002-11-11 | Method for manufacturing a stent |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2002339126A1 (en) |
GB (1) | GB0127033D0 (en) |
WO (1) | WO2003039407A2 (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10335192A1 (en) * | 2003-07-30 | 2005-03-03 | Phytis Medical Devices Gmbh | Medical implant for animal or human patient made of material allowing use of implant as visualization marker e.g. X-ray marker |
WO2005058537A2 (en) * | 2003-12-10 | 2005-06-30 | Boston Scientific Limited | Medical devices and methods of making the same |
EP1674596A1 (en) * | 2004-12-21 | 2006-06-28 | United Technologies Corporation | Laser enhancements of cold sprayed deposits |
WO2006082170A1 (en) * | 2005-02-02 | 2006-08-10 | Siemens Aktiengesellschaft | Cold gas spraying method |
WO2009059141A2 (en) * | 2007-11-02 | 2009-05-07 | Boston Scientific Limited | Stent with embedded material |
WO2009059180A2 (en) * | 2007-11-02 | 2009-05-07 | Boston Scientific Limited | Stent |
US7739781B2 (en) | 1996-12-30 | 2010-06-22 | Sorin Biomedica Cardio S.R.L | Process for producing a stent for angioplasty |
WO2011083321A1 (en) * | 2010-01-11 | 2011-07-14 | Smith & Nephew Plc | Medical device and method |
US8221822B2 (en) * | 2007-07-31 | 2012-07-17 | Boston Scientific Scimed, Inc. | Medical device coating by laser cladding |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2187988B1 (en) | 2007-07-19 | 2013-08-21 | Boston Scientific Limited | Endoprosthesis having a non-fouling surface |
WO2009020520A1 (en) | 2007-08-03 | 2009-02-12 | Boston Scientific Scimed, Inc. | Coating for medical device having increased surface area |
WO2009131911A2 (en) | 2008-04-22 | 2009-10-29 | Boston Scientific Scimed, Inc. | Medical devices having a coating of inorganic material |
WO2009132176A2 (en) | 2008-04-24 | 2009-10-29 | Boston Scientific Scimed, Inc. | Medical devices having inorganic particle layers |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2551770A1 (en) * | 1983-09-14 | 1985-03-15 | Honda Motor Co Ltd | METHOD FOR SURFACE TREATMENT OF A REFLECTIVE METAL PIECE AND PRODUCTS OBTAINED |
EP0824900A2 (en) * | 1996-08-22 | 1998-02-25 | Advanced Cardiovascular Systems, Inc. | Protective coating for a stent with intermediate radiopaque coating |
WO2001049340A1 (en) * | 1999-12-30 | 2001-07-12 | Advanced Cardiovascular Systems, Inc. | Stent with radiopaque coating consisting of particles in a binder |
WO2002026162A2 (en) * | 2000-09-26 | 2002-04-04 | Advanced Cardiovascular Systems, Inc. | A method of loading a substance onto an implantable device |
-
2001
- 2001-11-09 GB GBGB0127033.9A patent/GB0127033D0/en not_active Ceased
-
2002
- 2002-11-11 AU AU2002339126A patent/AU2002339126A1/en not_active Abandoned
- 2002-11-11 WO PCT/GB2002/005076 patent/WO2003039407A2/en not_active Application Discontinuation
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2551770A1 (en) * | 1983-09-14 | 1985-03-15 | Honda Motor Co Ltd | METHOD FOR SURFACE TREATMENT OF A REFLECTIVE METAL PIECE AND PRODUCTS OBTAINED |
EP0824900A2 (en) * | 1996-08-22 | 1998-02-25 | Advanced Cardiovascular Systems, Inc. | Protective coating for a stent with intermediate radiopaque coating |
WO2001049340A1 (en) * | 1999-12-30 | 2001-07-12 | Advanced Cardiovascular Systems, Inc. | Stent with radiopaque coating consisting of particles in a binder |
WO2002026162A2 (en) * | 2000-09-26 | 2002-04-04 | Advanced Cardiovascular Systems, Inc. | A method of loading a substance onto an implantable device |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7946019B2 (en) | 1996-12-30 | 2011-05-24 | Sorin Biomedica Cardio S.R.L. | Process for producing a stent for angioplasty |
US7739781B2 (en) | 1996-12-30 | 2010-06-22 | Sorin Biomedica Cardio S.R.L | Process for producing a stent for angioplasty |
DE10335192A1 (en) * | 2003-07-30 | 2005-03-03 | Phytis Medical Devices Gmbh | Medical implant for animal or human patient made of material allowing use of implant as visualization marker e.g. X-ray marker |
WO2005058537A2 (en) * | 2003-12-10 | 2005-06-30 | Boston Scientific Limited | Medical devices and methods of making the same |
WO2005058537A3 (en) * | 2003-12-10 | 2005-11-10 | Scimed Life Systems Inc | Medical devices and methods of making the same |
EP1674596A1 (en) * | 2004-12-21 | 2006-06-28 | United Technologies Corporation | Laser enhancements of cold sprayed deposits |
WO2006082170A1 (en) * | 2005-02-02 | 2006-08-10 | Siemens Aktiengesellschaft | Cold gas spraying method |
KR101254150B1 (en) * | 2005-02-02 | 2013-04-18 | 지멘스 악티엔게젤샤프트 | Cold gas spraying method |
US8021715B2 (en) | 2005-02-02 | 2011-09-20 | Siemens Aktiengesellschaft | Cold gas spraying method |
US8221822B2 (en) * | 2007-07-31 | 2012-07-17 | Boston Scientific Scimed, Inc. | Medical device coating by laser cladding |
WO2009059180A2 (en) * | 2007-11-02 | 2009-05-07 | Boston Scientific Limited | Stent |
WO2009059141A3 (en) * | 2007-11-02 | 2010-08-12 | Boston Scientific Limited | Stent with embedded material |
WO2009059180A3 (en) * | 2007-11-02 | 2009-09-24 | Boston Scientific Limited | Stent |
WO2009059141A2 (en) * | 2007-11-02 | 2009-05-07 | Boston Scientific Limited | Stent with embedded material |
WO2011083321A1 (en) * | 2010-01-11 | 2011-07-14 | Smith & Nephew Plc | Medical device and method |
Also Published As
Publication number | Publication date |
---|---|
WO2003039407A3 (en) | 2003-11-27 |
GB0127033D0 (en) | 2002-01-02 |
AU2002339126A1 (en) | 2003-05-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US7574799B2 (en) | Methods of making medical devices | |
US9675477B2 (en) | Welded stent having a welded soluble core | |
EP1974701B1 (en) | Stents incorporating radiopaque markers | |
WO2003039407A2 (en) | Method for manufacturing a stent | |
EP1652495B1 (en) | Expandable stent having a dissolvable portion | |
US9114032B1 (en) | Method of making a stent | |
US7674416B2 (en) | Hybrid intravascular stent | |
EP2353554B1 (en) | Stent | |
JP2008539889A (en) | Tubular stent and manufacturing method thereof | |
US20100217376A1 (en) | Medical devices | |
US20030065381A1 (en) | Longitudinal focussed force stent | |
EP2185109B1 (en) | Endoprostheses having porous claddings prepared using metal hydrides | |
US20080071344A1 (en) | Medical device with porous surface | |
EP1389451B1 (en) | Stent | |
EP1472991B1 (en) | Bifurcated stent with concentric body portions |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SC SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
122 | Ep: pct application non-entry in european phase | ||
NENP | Non-entry into the national phase in: |
Ref country code: JP |
|
WWW | Wipo information: withdrawn in national office |
Country of ref document: JP |