WO2003041763A3 - Intradermal delivery device and method - Google Patents

Intradermal delivery device and method Download PDF

Info

Publication number
WO2003041763A3
WO2003041763A3 PCT/US2002/036617 US0236617W WO03041763A3 WO 2003041763 A3 WO2003041763 A3 WO 2003041763A3 US 0236617 W US0236617 W US 0236617W WO 03041763 A3 WO03041763 A3 WO 03041763A3
Authority
WO
WIPO (PCT)
Prior art keywords
skin
syringe
housing
outer shell
elongated annular
Prior art date
Application number
PCT/US2002/036617
Other languages
French (fr)
Other versions
WO2003041763A2 (en
Inventor
Daniel Py
Julian V Chan
Original Assignee
Medical Instill Tech Inc
Py Daniel C
Julian V Chan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Instill Tech Inc, Py Daniel C, Julian V Chan filed Critical Medical Instill Tech Inc
Priority to AU2002346399A priority Critical patent/AU2002346399A1/en
Publication of WO2003041763A2 publication Critical patent/WO2003041763A2/en
Publication of WO2003041763A3 publication Critical patent/WO2003041763A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31591—Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3287—Accessories for bringing the needle into the body; Automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The subject intradermal delivery (110) device provides for penetration to a fixed depth without requiring special expertise by the user. The device consists of a syringe (112) nested inside an inner shell (114) and an outer shell (116) . A elongated annular channel (120) is formed between the inner shell (114) and the outer shell (116). A housing (118) recieves the syringe (112) and concentric shells in a sliding engagement. A first seal (122) on the distal end of the housing forms a variable length channel in communication with the elongated annular channel via a port formed in the outer shell (116). When the device is applied to the skin, the housing and syringe (112) are slid towards the skin, and the variable length channel generates a vacuum which forces the skin to bulge into the elongated annular channel. As a result, the skin is tensioned across the inner shell to form a substantially planar, taut target area of skin. The taut target area of skin in combination with a stop on the housing determines the insertion depth of the syringe (112).
PCT/US2002/036617 2001-11-14 2002-11-14 Intradermal delivery device and method WO2003041763A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002346399A AU2002346399A1 (en) 2001-11-14 2002-11-14 Intradermal delivery device and method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33269401P 2001-11-14 2001-11-14
US60/332,694 2001-11-14

Publications (2)

Publication Number Publication Date
WO2003041763A2 WO2003041763A2 (en) 2003-05-22
WO2003041763A3 true WO2003041763A3 (en) 2004-01-08

Family

ID=23299428

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/036617 WO2003041763A2 (en) 2001-11-14 2002-11-14 Intradermal delivery device and method

Country Status (3)

Country Link
US (1) US6971999B2 (en)
AU (1) AU2002346399A1 (en)
WO (1) WO2003041763A2 (en)

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AU2002346399A1 (en) 2003-05-26
US6971999B2 (en) 2005-12-06
US20030093032A1 (en) 2003-05-15
WO2003041763A2 (en) 2003-05-22

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