WO2003059934A3 - Albumin fusion proteins - Google Patents
Albumin fusion proteins Download PDFInfo
- Publication number
- WO2003059934A3 WO2003059934A3 PCT/US2002/040892 US0240892W WO03059934A3 WO 2003059934 A3 WO2003059934 A3 WO 2003059934A3 US 0240892 W US0240892 W US 0240892W WO 03059934 A3 WO03059934 A3 WO 03059934A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fusion proteins
- albumin fusion
- nucleic acids
- vectors
- host cells
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Abstract
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002484556A CA2484556A1 (en) | 2001-12-21 | 2002-12-23 | Albumin fusion proteins |
EP02799967A EP1463752A4 (en) | 2001-12-21 | 2002-12-23 | Albumin fusion proteins |
AU2002364587A AU2002364587A1 (en) | 2001-12-21 | 2002-12-23 | Albumin fusion proteins |
US10/775,180 US7189690B2 (en) | 2001-12-21 | 2004-02-11 | Albumin fusion proteins |
US11/393,893 US7238660B2 (en) | 2001-12-21 | 2006-03-31 | Albumin fusion proteins |
US11/772,591 US7977306B2 (en) | 2001-12-21 | 2007-07-02 | Albumin fusion proteins |
US13/078,804 US20130157933A1 (en) | 2001-12-21 | 2011-04-01 | Albumin fusion proteins |
US13/945,265 US20140328794A1 (en) | 2001-12-21 | 2013-07-18 | Albumin fusion proteins |
Applications Claiming Priority (30)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34181101P | 2001-12-21 | 2001-12-21 | |
US60/341,811 | 2001-12-21 | ||
US35035802P | 2002-01-24 | 2002-01-24 | |
US60/350,358 | 2002-01-24 | ||
US35937002P | 2002-02-26 | 2002-02-26 | |
US60/359,370 | 2002-02-26 | ||
US36000002P | 2002-02-28 | 2002-02-28 | |
US60/360,000 | 2002-02-28 | ||
US36750002P | 2002-03-27 | 2002-03-27 | |
US60/367,500 | 2002-03-27 | ||
US37022702P | 2002-04-08 | 2002-04-08 | |
US60/370,227 | 2002-04-08 | ||
US37895002P | 2002-05-10 | 2002-05-10 | |
US60/378,950 | 2002-05-10 | ||
US39800802P | 2002-07-24 | 2002-07-24 | |
US60/398,008 | 2002-07-24 | ||
US40213102P | 2002-08-09 | 2002-08-09 | |
US60/402,131 | 2002-08-09 | ||
US40270802P | 2002-08-13 | 2002-08-13 | |
US60/402,708 | 2002-08-13 | ||
US41135502P | 2002-09-18 | 2002-09-18 | |
US60/411,355 | 2002-09-18 | ||
US41498402P | 2002-10-02 | 2002-10-02 | |
US60/414,984 | 2002-10-02 | ||
US41761102P | 2002-10-11 | 2002-10-11 | |
US60/417,611 | 2002-10-11 | ||
US42024602P | 2002-10-23 | 2002-10-23 | |
US60/420,246 | 2002-10-23 | ||
US42362302P | 2002-11-05 | 2002-11-05 | |
US60/423,623 | 2002-11-05 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/775,180 Continuation US7189690B2 (en) | 2001-12-21 | 2004-02-11 | Albumin fusion proteins |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003059934A2 WO2003059934A2 (en) | 2003-07-24 |
WO2003059934A3 true WO2003059934A3 (en) | 2004-02-26 |
Family
ID=27585554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/040892 WO2003059934A2 (en) | 2001-12-21 | 2002-12-23 | Albumin fusion proteins |
Country Status (5)
Country | Link |
---|---|
US (5) | US7189690B2 (en) |
EP (1) | EP1463752A4 (en) |
AU (1) | AU2002364587A1 (en) |
CA (1) | CA2484556A1 (en) |
WO (1) | WO2003059934A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8993517B2 (en) | 2001-12-21 | 2015-03-31 | Human Genome Sciences, Inc. | Albumin fusion proteins |
Families Citing this family (145)
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WO2003042354A2 (en) | 2001-09-04 | 2003-05-22 | Aventis Pharmaceuticals Inc. | Abrogen polypeptides, nucleic acids encoding them and methods for using them to inhibit angiogenesis |
WO2003030821A2 (en) | 2001-10-05 | 2003-04-17 | Human Genome Sciences, Inc. | Albumin fusion proteins |
US20080194481A1 (en) | 2001-12-21 | 2008-08-14 | Human Genome Sciences, Inc. | Albumin Fusion Proteins |
KR101271635B1 (en) | 2001-12-21 | 2013-06-12 | 휴먼 게놈 사이언시즈, 인코포레이티드 | Albumin fusion proteins |
EP1463752A4 (en) | 2001-12-21 | 2005-07-13 | Human Genome Sciences Inc | Albumin fusion proteins |
EP2277889B1 (en) | 2001-12-21 | 2014-07-09 | Human Genome Sciences, Inc. | Fusion proteins of albumin and interferon beta |
CN1241946C (en) * | 2002-07-01 | 2006-02-15 | 美国福源集团 | Human serum albumins recombined merge protein having hyperplasia stimulation function to multiple cells |
US6913890B2 (en) | 2002-12-18 | 2005-07-05 | Palo Alto Research Center Incorporated | Process for preparing albumin protein conjugated oligonucleotide probes |
CA2513213C (en) | 2003-01-22 | 2013-07-30 | Human Genome Sciences, Inc. | Albumin fusion proteins |
BRPI0411132B8 (en) | 2003-06-12 | 2021-05-25 | Lilly Co Eli | heterologous fusion protein and its uses |
BRPI0507026A (en) | 2004-02-09 | 2007-04-17 | Human Genome Sciences Inc | albumin fusion proteins |
AU2007258609B2 (en) | 2006-06-07 | 2013-01-24 | Human Genome Sciences, Inc. | Albumin fusion proteins |
-
2002
- 2002-12-23 EP EP02799967A patent/EP1463752A4/en not_active Withdrawn
- 2002-12-23 WO PCT/US2002/040892 patent/WO2003059934A2/en active Search and Examination
- 2002-12-23 AU AU2002364587A patent/AU2002364587A1/en not_active Abandoned
- 2002-12-23 CA CA002484556A patent/CA2484556A1/en not_active Abandoned
-
2004
- 2004-02-11 US US10/775,180 patent/US7189690B2/en not_active Expired - Lifetime
-
2006
- 2006-03-31 US US11/393,893 patent/US7238660B2/en not_active Expired - Lifetime
-
2007
- 2007-07-02 US US11/772,591 patent/US7977306B2/en not_active Expired - Lifetime
-
2011
- 2011-04-01 US US13/078,804 patent/US20130157933A1/en not_active Abandoned
-
2013
- 2013-07-18 US US13/945,265 patent/US20140328794A1/en not_active Abandoned
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US5876969A (en) * | 1992-01-31 | 1999-03-02 | Fleer; Reinhard | Fusion polypeptides comprising human serum albumin, nucleic acids encoding same, and recombinant expression thereof |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8993517B2 (en) | 2001-12-21 | 2015-03-31 | Human Genome Sciences, Inc. | Albumin fusion proteins |
Also Published As
Publication number | Publication date |
---|---|
EP1463752A4 (en) | 2005-07-13 |
CA2484556A1 (en) | 2003-07-24 |
AU2002364587A1 (en) | 2003-07-30 |
US7238660B2 (en) | 2007-07-03 |
US20060286635A1 (en) | 2006-12-21 |
EP1463752A2 (en) | 2004-10-06 |
US20140328794A1 (en) | 2014-11-06 |
US20050054570A1 (en) | 2005-03-10 |
US20130157933A1 (en) | 2013-06-20 |
WO2003059934A2 (en) | 2003-07-24 |
US7977306B2 (en) | 2011-07-12 |
AU2002364587A8 (en) | 2003-07-30 |
US20080293629A1 (en) | 2008-11-27 |
US7189690B2 (en) | 2007-03-13 |
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