WO2003063737A1 - Intra-ocular lens provided with adhesive on its external border - Google Patents

Intra-ocular lens provided with adhesive on its external border Download PDF

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Publication number
WO2003063737A1
WO2003063737A1 PCT/DE2003/000102 DE0300102W WO03063737A1 WO 2003063737 A1 WO2003063737 A1 WO 2003063737A1 DE 0300102 W DE0300102 W DE 0300102W WO 03063737 A1 WO03063737 A1 WO 03063737A1
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WO
WIPO (PCT)
Prior art keywords
adhesive
lens
intraocular lens
edge
capsular bag
Prior art date
Application number
PCT/DE2003/000102
Other languages
German (de)
French (fr)
Inventor
Herbert Von Wallfeld
Original Assignee
Technomed Gesellschaft Für Med.Und Med. -Techn. Systems Mbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technomed Gesellschaft Für Med.Und Med. -Techn. Systems Mbh filed Critical Technomed Gesellschaft Für Med.Und Med. -Techn. Systems Mbh
Priority to DE10390231T priority Critical patent/DE10390231D2/en
Publication of WO2003063737A1 publication Critical patent/WO2003063737A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2002/16965—Lens includes ultraviolet absorber
    • A61F2002/1699—Additional features not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30448—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008—Fixation appliances for connecting prostheses to the body

Definitions

  • the invention relates to an intraocular lens having an outer edge.
  • Intraocular lenses are usually attached with a special feel in the capsular bag of an eye. Especially when the lenses are very thin, problems arise when attaching the lens to the haptic and placing the haptic in the capsular bag of the eye, which are mainly due to a bending of the implants in the eye.
  • the invention has the object to further develop an intraocular lens so that they easier, z. B. without haptics to attach in the eye.
  • the outer edge has an adhesive.
  • the attachment of an adhesive on the outer edge of the lens makes it possible to fix the lens during insertion of the lens into the capsular bag, preferably without a haptic in the capsular bag. It is advantageous if the adhesive fixes the lens in the capsular bag at least until a firm connection has formed between the lens and the capsular bag as a result of the healing of the procedure. It is desirable if the fixation is permanent.
  • a simple procedure when inserting the lens results from the fact that the adhesive is activated.
  • the adhesive may be exposed through a peelable top layer, such as a silicone film, just prior to surgery. As a result, contamination of the adhesive is avoided before activation. However, the adhesive is only secondary z. B.
  • irradiation such as UV light or heat activatable to convert the adhesive into a sticky form or cure by the irradiation.
  • Other options for activation include treatment with microwaves or moisture.
  • the adhesive is thus either directly active or secondarily activated.
  • the provision of the adhesive between the lens and the capsular bag further prevents cells between the lens and the capsular bag from penetrating from the area in front of the lens into the area behind the lens.
  • the provision of an adhesive between the intraocular lens and the capsular bag thus prevents the risk of after-stars caused by the turbidity on the lens back by such cells.
  • the adhesive be applied as a closed line.
  • the closed line makes it possible to securely seal the space in front of the lens against the space behind the lens by means of the glue.
  • the secure hold of the lens in the capsular bag and the Ve ⁇ neiden of migratory cells is also achieved in that the edge of the intraocular lens has an edge.
  • the fact that the rounded surfaces of the lens leak at the edge into an edge, a better anchoring of the lens in the capsular bag and a better seal between the capsular bag and lens is achieved.
  • the edge has an acute angle. This makes it possible to firmly anchor the lens in the capsular bag.
  • the lens is foldable or injectable.
  • the attached drawing shows a Ausfiilirungsbeispiel an intraocular lens according to the invention.
  • FIG. 1 is a schematic plan view of an intraocular lens
  • FIG. 2 shows a section through the intraocular lens shown in FIG.
  • the intraocular lens 1 is made of polymethyl methacrylate (PMMA). But it can also be made of silicone, other acrylics, polyurethane or other materials.
  • PMMA polymethyl methacrylate
  • the section shows the lenticular shape. In the plan view, the lens is circular. It therefore has a nikfö ⁇ nigen outer edge 2, which in the present case has a sharp edge with an angle 3 of about 45 °. For very thin lenses, the angle 3 to be measured at the edge is less than 45 °.
  • the circular edge 2 abuts against the capsular bag 4 indicated in the figure and on both sides of the edge 2 adhesive surfaces 5 and 6 are arranged annularly, which allow the lens 1 to be bonded to the capsular bag 4.
  • the adhesive can also be attached only on one side of the lens or directly on the edge of the lens.
  • the adhesive is cured with UV light.
  • the plano-convex intraocular lens 7 shown in FIG. 3 has a holding web 8 which is fastened to the intraocular lens 7 and has an adhesive edge 9.
  • the adhesive edge is arranged in this exemplary embodiment on the retaining bar radially outside the lens area. It runs in such a way subsequent to the course of the convex side of the lens, that behind the lens, a cavity 9 is formed.

Abstract

The invention relates to an intra-ocular lens (1) comprising an adhesive (5, 6) on its external border (2). Said adhesive (5, 6) can preferably be activated by UV light. In addition the external border (2) of the lens (1) is not curved but configured as an edge (2). This facilitates the fixing of the lens in the capsular sac, reduces the risk of a secondary cataract and optionally permits a larger optical device.

Description

INTRAOKULARLINSE MIT EINEM KLEBER AUF DEM AUSSEREN RAND INTRAOCULAR LENS WITH AN ADHESIVE ON THE OUTSIDE EDGE
Die Erfindung betrifft eine Intraokularlinse mit einem äußeren Rand.The invention relates to an intraocular lens having an outer edge.
Intraokularlinsen werden in der Regel mit einer speziellen Haptik im Kapselsack eines Auges befestigt. Vor allem wenn die Linsen sehr dünn sind, entstehen Probleme beim Befestigen der Linse an der Haptik und beim Anordnen der Haptik im Kapselsack des Auges, die vor allem auf eine Verbiegung der Implantate im Auge zurückzuführen sind.Intraocular lenses are usually attached with a special feel in the capsular bag of an eye. Especially when the lenses are very thin, problems arise when attaching the lens to the haptic and placing the haptic in the capsular bag of the eye, which are mainly due to a bending of the implants in the eye.
Der Erfindung liegt die Aufgabe zugrunde, eine Intraokularlinse derart weiterzubilden, dass sie leichter, z. B. auch ohne Haptiken, im Auge zu befestigen ist.The invention has the object to further develop an intraocular lens so that they easier, z. B. without haptics to attach in the eye.
Diese Aufgabe wird dadurch gelöst, dass der äußere Rand einen Kleber aufweist. Das Anbringen eines Klebers am äußeren Rand der Linse ermöglicht es, die Linse bei dem Einsetzen der Linse in den Kapselsack vorzugsweise ohne eine Haptik im Kapselsack zu fixieren. Vorteilhaft ist es, wenn der Kleber die Linse im Kapselsack mindestens solange fixiert, bis durch das Abheilen des Eingriffs eine feste Verbindung zwischen der Linse und dem Kapselsack entstanden ist. Wünschenswert ist es, wenn die Fixierung dauerhaft ist. Eine einfache Vorgehensweise beim Einsetzen der Linse ergibt sich dadurch, dass der Kleber aktivierbar ist. Der Kleber kann beispielsweise durch eine abziehbare obere Schicht, wie beispielsweise eine Silikonfolie kurz vor der Operation freigelegt werden. Dadurch wird eine Verschmutzung des Klebers vor der Aktivierung vermieden. Der Kleber ist jedoch auch erst sekundär z. B. durch eine spezielle Bestrahlung, wie beispielsweise mit UV-Licht oder Wärme aktivierbar, um den Kleber in eine klebrige Form zu überführen oder durch die Bestrahlung auszuhärten. Weitere Möglichkeiten der Aktivierung erschließt eine Behandlung mit Mikrowellen oder Feuchtigkeit. Der Kleber ist somit entweder direkt aktiv oder sekundär aktivierbar.This object is achieved in that the outer edge has an adhesive. The attachment of an adhesive on the outer edge of the lens makes it possible to fix the lens during insertion of the lens into the capsular bag, preferably without a haptic in the capsular bag. It is advantageous if the adhesive fixes the lens in the capsular bag at least until a firm connection has formed between the lens and the capsular bag as a result of the healing of the procedure. It is desirable if the fixation is permanent. A simple procedure when inserting the lens results from the fact that the adhesive is activated. For example, the adhesive may be exposed through a peelable top layer, such as a silicone film, just prior to surgery. As a result, contamination of the adhesive is avoided before activation. However, the adhesive is only secondary z. B. by a special irradiation, such as UV light or heat activatable to convert the adhesive into a sticky form or cure by the irradiation. Other options for activation include treatment with microwaves or moisture. The adhesive is thus either directly active or secondarily activated.
Das Vorsehen des Klebers zwischen der Linse und dem Kapselsack verhindert weiterhin, dass Zellen zwischen Linse und Kapselsack aus dem Bereich vor der Linse in den Bereich hinter der Linse penetrieren. Das Vorsehen eines Klebers zwischen Intraokularlinse und Kapselsack verhindert somit die Gefahr eines Nach-Stars, der durch die Trübung an der Linsenrückseite durch derartige Zellen verursacht wird.The provision of the adhesive between the lens and the capsular bag further prevents cells between the lens and the capsular bag from penetrating from the area in front of the lens into the area behind the lens. The provision of an adhesive between the intraocular lens and the capsular bag thus prevents the risk of after-stars caused by the turbidity on the lens back by such cells.
Um sicher zu verhindern, dass zwischen Intraokularlinse und Kapselsack Zellen an der Linse vorbei wandern, wird vorgeschlagen, dass der Kleber als geschlossene Linie aufgebracht ist. Die geschlossene Linie ermöglicht es, den Raum vor der Linse gegen den Raum hinter der Linse mittels des Klebers sicher abzudichten. Der sichere Halt der Linse im Kapselsack und das Veπneiden von wandernden Zellen wird auch dadurch erzielt, dass der Rand der Intraokularlinse eine Kante hat. Dadurch, dass die gerundeten Oberflächen der Linse am Rand in eine Kante auslaufen, wird eine bessere Verankerung der Linse im Kapselsack und eine bessere Abdichtung zwischen Kapselsack und Linse erzielt.In order to reliably prevent cells from migrating past the lens between the intraocular lens and the capsular bag, it is proposed that the adhesive be applied as a closed line. The closed line makes it possible to securely seal the space in front of the lens against the space behind the lens by means of the glue. The secure hold of the lens in the capsular bag and the Veπneiden of migratory cells is also achieved in that the edge of the intraocular lens has an edge. The fact that the rounded surfaces of the lens leak at the edge into an edge, a better anchoring of the lens in the capsular bag and a better seal between the capsular bag and lens is achieved.
Vorteilhaft ist es, wenn die Kante einen spitzen Winkel aufweist. Dies eπnöglicht es, die Linse fest im Kapselsack zu verankern.It is advantageous if the edge has an acute angle. This makes it possible to firmly anchor the lens in the capsular bag.
Vorteilhaft ist es, wenn eine derartige Linse so ausgebildet ist, dass sie ohne Haptik in den Kapselsack einklebbar ist. Dies reduziert die für die Haptik notwendigen Kosten und ermöglicht ggf. eine größere Optik.It is advantageous if such a lens is designed so that it can be pasted into the capsular bag without haptics. This reduces the costs necessary for the feel and possibly allows a larger appearance.
Um das Einsetzen der Linse zu erleichtern ist es vorteilhaft, wenn die Linse faltbar oder injizierbar ist.To facilitate the insertion of the lens, it is advantageous if the lens is foldable or injectable.
Die beiliegende Zeichnung zeigt ein Ausfiilirungsbeispiel einer erfindungsgemäßen Intraokularlinse.The attached drawing shows a Ausfiilirungsbeispiel an intraocular lens according to the invention.
Es zeigtIt shows
Figur 1 schematisch eine Draufsicht auf eine Intraokularlinse,FIG. 1 is a schematic plan view of an intraocular lens;
Figur 2 einen Schnitt durch die in Figur 1 gezeigte Intraokularlinse undFIG. 2 shows a section through the intraocular lens shown in FIG
Figur 3 einen Schnitt durch eine Plankonvexe Intraokularlinse mit einem Stegring. Die Intraokularlinse 1 ist aus Polymethylmetacrylat (PMMA) hergestellt. Sie kann aber auch aus Silikon, anderen Acrylen, Polyurethan oder anderen Materialien hergestellt werden. Der Schnitt zeigt die linsenföπnige Form. In der Draufsicht ist die Linse kreisförmig ausgebildet. Sie hat daher einen kreisföπnigen äußeren Rand 2, der im vorliegenden Fall eine scharfe Kante mit einem Winkel 3 von etwa 45 ° aufweist. Bei besonders dünnen Linsen ist der an der Kante zu messende Winkel 3 kleiner als 45 °. Die kreisrunde Kante 2 liegt an dem in der Figur angedeuteten Kapselsack 4 an und beidseitig der Kante 2 sind ringförmig Klebeflächen 5 und 6 angeordnet, die es erlauben die Linse 1 mit dem Kapselsack 4 zu verkleben. Der Kleber kann aber auch nur einseitig der Linse oder direkt am Linsenrand angebracht werden.3 shows a section through a plano-convex intraocular lens with a web ring. The intraocular lens 1 is made of polymethyl methacrylate (PMMA). But it can also be made of silicone, other acrylics, polyurethane or other materials. The section shows the lenticular shape. In the plan view, the lens is circular. It therefore has a kreisföπnigen outer edge 2, which in the present case has a sharp edge with an angle 3 of about 45 °. For very thin lenses, the angle 3 to be measured at the edge is less than 45 °. The circular edge 2 abuts against the capsular bag 4 indicated in the figure and on both sides of the edge 2 adhesive surfaces 5 and 6 are arranged annularly, which allow the lens 1 to be bonded to the capsular bag 4. The adhesive can also be attached only on one side of the lens or directly on the edge of the lens.
Um eine schnelle Härtung des Klebers zu erzielen, wird der Klebstoff mit UV-Licht ausgehärtet.To achieve a fast curing of the adhesive, the adhesive is cured with UV light.
Die in Figur 3 gezeigte plankonvexe Intraokularlinse 7 hat einen Haltesteg 8 der an der Intraokularlinse 7 befestigt ist und einen Kleberand 9 aufweist. Der Kleberand ist in diesem Ausfiihrungsbeispiel auf dem Haltesteg radial außerhalb des Linsenbereiches angeordnet. Er verläuft derart anschließend an den Verlauf der konvexen Seite der Linse, dass hinter der Linse ein Hohlraum 9 entsteht. The plano-convex intraocular lens 7 shown in FIG. 3 has a holding web 8 which is fastened to the intraocular lens 7 and has an adhesive edge 9. The adhesive edge is arranged in this exemplary embodiment on the retaining bar radially outside the lens area. It runs in such a way subsequent to the course of the convex side of the lens, that behind the lens, a cavity 9 is formed.

Claims

Patentansprüche: claims:
1. Intraokularlinse (1) mit einem äußeren Rand (2), dadurch gekennzeichnet, dass der äußere Rand (2) einen Kleber (5, 6) aufweist.1. intraocular lens (1) having an outer edge (2), characterized in that the outer edge (2) has an adhesive (5, 6).
2. Intraokularlinse (1) nach Anspruch 1, dadurch gekennzeichnet, dass der Kleber (5, 6) aktivierbar ist.2. intraocular lens (1) according to claim 1, characterized in that the adhesive (5, 6) is activated.
3. Intraokularlinse (1) nach Anspruch 2, dadurch gekennzeichnet, dass der Kleber (5, 6) durch UV-Licht aktivierbar ist.3. intraocular lens (1) according to claim 2, characterized in that the adhesive (5, 6) is activated by UV light.
4. Intraokularlinse (1) nach Anspruch 2, dadurch gekennzeichnet, dass der Kleber (5, 6) durch Wärme aktivierbar ist.4. intraocular lens (1) according to claim 2, characterized in that the adhesive (5, 6) is activated by heat.
5. Intraokularlinse (1) nach Anspruch 2, dadurch gekennzeichnet, dass der Kleber (5, 6) durch Feuchtigkeit aktivierbar ist.5. intraocular lens (1) according to claim 2, characterized in that the adhesive (5, 6) is activated by moisture.
6. Intraokularlinse (1) nach Anspruch 2, dadurch gekennzeichnet, dass der Kleber (5, 6) durch Mikrowellen aktivierbar ist.6. intraocular lens (1) according to claim 2, characterized in that the adhesive (5, 6) can be activated by microwaves.
7. Intraokularlinse (1) nach einem der vorhergehend beschriebenen Ansprüche, dadurch gekennzeichnet, dass der Kleber (5, 6) als geschlossene Linie aufgetragen ist.7. intraocular lens (1) according to one of the preceding claims, characterized in that the adhesive (5, 6) is applied as a closed line.
8. Intraokularlinse (1), dadurch gekennzeichnet, dass der Rand eine Kante (2) hat. 8. intraocular lens (1), characterized in that the edge has an edge (2).
9. Intraokularlinse(l) nach Anspruch 8, dadurch gekennzeichnet, dass die Kante (2) einen spitzen Winkel (3) aufweist.9. intraocular lens (I) according to claim 8, characterized in that the edge (2) has an acute angle (3).
10. Intraokularlinse (1) nach einem der vorhergehend bescliriebenen Ansprüche, dadurch gekennzeichnet, dass die Linse (1) ohne Haptik in den Kapselsack (4) einklebbar ist. 10. Intraocular lens (1) according to one of the preceding claims, characterized in that the lens (1) can be adhesively bonded into the capsular bag (4) without haptic.
PCT/DE2003/000102 2002-01-30 2003-01-16 Intra-ocular lens provided with adhesive on its external border WO2003063737A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE10390231T DE10390231D2 (en) 2002-01-30 2003-01-16 Intraocular lens with a glue on the outside edge

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10204605.0 2002-01-30
DE2002104605 DE10204605A1 (en) 2002-01-30 2002-01-30 Intraocular lens with an outer edge

Publications (1)

Publication Number Publication Date
WO2003063737A1 true WO2003063737A1 (en) 2003-08-07

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ID=7713693

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PCT/DE2003/000102 WO2003063737A1 (en) 2002-01-30 2003-01-16 Intra-ocular lens provided with adhesive on its external border

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DE (2) DE10204605A1 (en)
WO (1) WO2003063737A1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002571A (en) * 1989-02-06 1991-03-26 Donnell Jr Francis E O Intraocular lens implant and method of locating and adhering within the posterior chamber
US5133747A (en) * 1990-03-16 1992-07-28 Feaster Fred T Epiphakic intraocular lens and process of implantation
US5354336A (en) * 1991-01-29 1994-10-11 Autogenesis Technologies, Inc. Method for bonding soft tissue with collagen-based adhesives and sealants
US5669934A (en) * 1991-02-13 1997-09-23 Fusion Medical Technologies, Inc. Methods for joining tissue by applying radiofrequency energy to performed collagen films and sheets

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002571A (en) * 1989-02-06 1991-03-26 Donnell Jr Francis E O Intraocular lens implant and method of locating and adhering within the posterior chamber
US5133747A (en) * 1990-03-16 1992-07-28 Feaster Fred T Epiphakic intraocular lens and process of implantation
US5354336A (en) * 1991-01-29 1994-10-11 Autogenesis Technologies, Inc. Method for bonding soft tissue with collagen-based adhesives and sealants
US5669934A (en) * 1991-02-13 1997-09-23 Fusion Medical Technologies, Inc. Methods for joining tissue by applying radiofrequency energy to performed collagen films and sheets

Also Published As

Publication number Publication date
DE10390231D2 (en) 2004-12-23
DE10204605A1 (en) 2003-07-31

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