WO2003066832A3 - Generation of new insulin cells from progenitor cells present in adult pancreatic islets - Google Patents
Generation of new insulin cells from progenitor cells present in adult pancreatic islets Download PDFInfo
- Publication number
- WO2003066832A3 WO2003066832A3 PCT/US2003/003859 US0303859W WO03066832A3 WO 2003066832 A3 WO2003066832 A3 WO 2003066832A3 US 0303859 W US0303859 W US 0303859W WO 03066832 A3 WO03066832 A3 WO 03066832A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- insulin
- producing cells
- generation
- cells
- pancreatic islets
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/34—Sugars
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003217357A AU2003217357A1 (en) | 2002-02-07 | 2003-02-07 | Generation of new insulin cells from progenitor cells present in adult pancreatic islets |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35571502P | 2002-02-07 | 2002-02-07 | |
US60/355,715 | 2002-02-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003066832A2 WO2003066832A2 (en) | 2003-08-14 |
WO2003066832A3 true WO2003066832A3 (en) | 2003-12-24 |
Family
ID=27734554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/003859 WO2003066832A2 (en) | 2002-02-07 | 2003-02-07 | Generation of new insulin cells from progenitor cells present in adult pancreatic islets |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2003217357A1 (en) |
WO (1) | WO2003066832A2 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
US9234172B2 (en) | 2003-06-27 | 2016-01-12 | DePuy Synthes Products, Inc. | Repair and regeneration of ocular tissue using postpartum-derived cells |
US9498501B2 (en) | 2003-06-27 | 2016-11-22 | DePuy Synthes Products, Inc. | Postpartum cells derived from umbilical cord tissue, and methods of making and using the same |
US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7875272B2 (en) | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
CA2589063C (en) | 2004-12-23 | 2016-08-09 | Ethicon Incorporated | Treatment of parkinson's disease and related disorders using postpartum derived cells |
US9175261B2 (en) | 2005-12-16 | 2015-11-03 | DePuy Synthes Products, Inc. | Human umbilical cord tissue cells for inhibiting adverse immune response in histocompatibility-mismatched transplantation |
AU2009327384B2 (en) | 2008-12-19 | 2014-07-10 | DePuy Synthes Products, LLC | Treatment of lung and pulmonary diseases and disorders |
US10179900B2 (en) | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
EP2411504B1 (en) | 2009-03-26 | 2017-05-10 | DePuy Synthes Products, Inc. | Human umbilical cord tissue cells as therapy for alzheimer's disease |
US9611513B2 (en) | 2011-12-23 | 2017-04-04 | DePuy Synthes Products, Inc. | Detection of human umbilical cord tissue derived cells |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5116753A (en) * | 1991-07-30 | 1992-05-26 | The Salk Institute For Biological Studies | Maintenance of pancreatic islets |
US5858973A (en) * | 1994-02-23 | 1999-01-12 | The General Hospital Corporation | Transcription factor and uses therefor |
US6020200A (en) * | 1995-03-03 | 2000-02-01 | Metabolex, Inc. | Encapsulation compositions and methods |
US6149907A (en) * | 1994-04-13 | 2000-11-21 | Research Corporation Technologies, Inc. | Treatments using sertoli cells |
-
2003
- 2003-02-07 AU AU2003217357A patent/AU2003217357A1/en not_active Abandoned
- 2003-02-07 WO PCT/US2003/003859 patent/WO2003066832A2/en not_active Application Discontinuation
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5116753A (en) * | 1991-07-30 | 1992-05-26 | The Salk Institute For Biological Studies | Maintenance of pancreatic islets |
US5858973A (en) * | 1994-02-23 | 1999-01-12 | The General Hospital Corporation | Transcription factor and uses therefor |
US6149907A (en) * | 1994-04-13 | 2000-11-21 | Research Corporation Technologies, Inc. | Treatments using sertoli cells |
US6020200A (en) * | 1995-03-03 | 2000-02-01 | Metabolex, Inc. | Encapsulation compositions and methods |
Non-Patent Citations (3)
Title |
---|
EIZIRIK ET AL.: "Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induced long-lasting functional impairment of beta-cells", BIOCHEMICAL PHARMACOLOGY, vol. 42, no. 12, 1991, pages 2275 - 2282, XP002967912 * |
FISHER ET AL.: "Inhibition of alloxan action in isolated pancreatic islets by superoxide dismutase, catalase and a metal chelator", DIABETES, vol. 29, March 1980 (1980-03-01), pages 213 - 216, XP002967914 * |
SUAREZ-PINZON ET AL.: "An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitric prevents diabetes development in NOD mice", JOURNAL OF AUTOIMMUNITY, vol. 16, 2001, pages 449 - 455, XP002967913 * |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9234172B2 (en) | 2003-06-27 | 2016-01-12 | DePuy Synthes Products, Inc. | Repair and regeneration of ocular tissue using postpartum-derived cells |
US9498501B2 (en) | 2003-06-27 | 2016-11-22 | DePuy Synthes Products, Inc. | Postpartum cells derived from umbilical cord tissue, and methods of making and using the same |
US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
US9585918B2 (en) | 2005-12-28 | 2017-03-07 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
Also Published As
Publication number | Publication date |
---|---|
AU2003217357A8 (en) | 2003-09-02 |
WO2003066832A2 (en) | 2003-08-14 |
AU2003217357A1 (en) | 2003-09-02 |
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