WO2003072036A2 - Treatment methods using anti-cd22 antibodies - Google Patents
Treatment methods using anti-cd22 antibodies Download PDFInfo
- Publication number
- WO2003072036A2 WO2003072036A2 PCT/US2003/005323 US0305323W WO03072036A2 WO 2003072036 A2 WO2003072036 A2 WO 2003072036A2 US 0305323 W US0305323 W US 0305323W WO 03072036 A2 WO03072036 A2 WO 03072036A2
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- WIPO (PCT)
- Prior art keywords
- sequence
- antibody
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- treatment
- amino acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE60334364T DE60334364D1 (en) | 2002-02-21 | 2003-02-21 | TREATMENT PROCEDURE USING ANTI-CD22 ANTIBODIES |
EP03711190A EP1476120B1 (en) | 2002-02-21 | 2003-02-21 | Treatment methods using anti-cd22 antibodies |
CA002475509A CA2475509A1 (en) | 2002-02-21 | 2003-02-21 | Treatment methods using anti-cd22 antibodies |
JP2003570783A JP2005526044A (en) | 2002-02-21 | 2003-02-21 | Treatment method using anti-CD22 antibody |
AT03711190T ATE482719T1 (en) | 2002-02-21 | 2003-02-21 | TREATMENT METHODS USING ANTI-CD22 ANTIBODIES |
AU2003215365A AU2003215365A1 (en) | 2002-02-21 | 2003-02-21 | Treatment methods using anti-cd22 antibodies |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35941902P | 2002-02-21 | 2002-02-21 | |
US60/359,419 | 2002-02-21 | ||
US42047202P | 2002-10-21 | 2002-10-21 | |
US60/420,472 | 2002-10-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003072036A2 true WO2003072036A2 (en) | 2003-09-04 |
WO2003072036A3 WO2003072036A3 (en) | 2003-12-31 |
Family
ID=27767572
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/005549 WO2003072736A2 (en) | 2002-02-21 | 2003-02-21 | Reagents and treatment methods for autoimmune diseases |
PCT/US2003/005323 WO2003072036A2 (en) | 2002-02-21 | 2003-02-21 | Treatment methods using anti-cd22 antibodies |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/005549 WO2003072736A2 (en) | 2002-02-21 | 2003-02-21 | Reagents and treatment methods for autoimmune diseases |
Country Status (10)
Country | Link |
---|---|
US (5) | US20040001828A1 (en) |
EP (2) | EP1485130A4 (en) |
JP (3) | JP2005526501A (en) |
KR (1) | KR20040094705A (en) |
CN (1) | CN1646161A (en) |
AT (1) | ATE482719T1 (en) |
AU (2) | AU2003215365A1 (en) |
CA (2) | CA2476776A1 (en) |
DE (1) | DE60334364D1 (en) |
WO (2) | WO2003072736A2 (en) |
Cited By (103)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1485130A2 (en) * | 2002-02-21 | 2004-12-15 | Duke University | Reagents and treatment methods for autoimmune diseases |
WO2005117986A2 (en) * | 2004-06-01 | 2005-12-15 | Genentech, Inc. | Antibody drug conjugates and methods |
WO2006054059A1 (en) * | 2004-11-19 | 2006-05-26 | Ucb Pharma S.A. | Neutralising antibody molecules having specificity for human il-17 |
WO2006066049A3 (en) * | 2004-12-15 | 2006-10-05 | Neuralab Ltd | Humanized antibodies that recognize beta amyloid peptide |
JP2007516242A (en) * | 2003-11-17 | 2007-06-21 | ジェネンテック・インコーポレーテッド | Compositions and methods for the treatment of tumors of hematopoietic origin |
US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
EP2260858A2 (en) | 2003-11-06 | 2010-12-15 | Seattle Genetics, Inc. | Monomethylvaline compounds capable of conjugation to ligands |
WO2011000054A1 (en) | 2009-07-03 | 2011-01-06 | Avipep Pty Ltd | Immuno-conjugates and methods for producing them |
US7871615B2 (en) | 2003-05-30 | 2011-01-18 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
US7893214B2 (en) | 1997-12-02 | 2011-02-22 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
WO2011031870A1 (en) | 2009-09-09 | 2011-03-17 | Centrose, Llc | Extracellular targeted drug conjugates |
WO2011056983A1 (en) | 2009-11-05 | 2011-05-12 | Genentech, Inc. | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
WO2011075786A1 (en) | 2009-12-23 | 2011-06-30 | Avipep Pty Ltd | Immuno-conjugates and methods for producing them 2 |
US8003097B2 (en) | 2007-04-18 | 2011-08-23 | Janssen Alzheimer Immunotherapy | Treatment of cerebral amyloid angiopathy |
US8034339B2 (en) | 1997-12-02 | 2011-10-11 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidogenic disease |
WO2011130598A1 (en) | 2010-04-15 | 2011-10-20 | Spirogen Limited | Pyrrolobenzodiazepines and conjugates thereof |
WO2011156328A1 (en) | 2010-06-08 | 2011-12-15 | Genentech, Inc. | Cysteine engineered antibodies and conjugates |
US8088378B2 (en) | 2007-07-16 | 2012-01-03 | Genetech Inc. | Anti-CD79B antibodies and immunoconjugates and methods of use |
US8128928B2 (en) | 2002-03-12 | 2012-03-06 | Wyeth Llc | Humanized antibodies that recognize beta amyloid peptide |
WO2012074757A1 (en) | 2010-11-17 | 2012-06-07 | Genentech, Inc. | Alaninyl maytansinol antibody conjugates |
US8226945B2 (en) | 2006-05-30 | 2012-07-24 | Genentech, Inc. | Antibodies and immunoconjugates and uses therefor |
WO2012142662A1 (en) | 2011-04-21 | 2012-10-26 | Garvan Institute Of Medical Research | Modified variable domain molecules and methods for producing and using them b |
WO2012155019A1 (en) | 2011-05-12 | 2012-11-15 | Genentech, Inc. | Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature pepides |
EP2535357A1 (en) * | 2007-07-12 | 2012-12-19 | Pierre Fabre Medicament | Novel antibodies inhibiting C-MET dimerization, and uses thereof |
US8389688B2 (en) | 2006-03-06 | 2013-03-05 | Aeres Biomedical, Ltd. | Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
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WO2013130093A1 (en) | 2012-03-02 | 2013-09-06 | Genentech, Inc. | Biomarkers for treatment with anti-tubulin chemotherapeutic compounds |
US8580265B2 (en) | 2011-01-14 | 2013-11-12 | Ucb Pharma S.A. | Antibody molecules which bind IL-17A and IL-17F |
US8613920B2 (en) | 2007-07-27 | 2013-12-24 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
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US9067981B1 (en) | 2008-10-30 | 2015-06-30 | Janssen Sciences Ireland Uc | Hybrid amyloid-beta antibodies |
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WO2016040825A1 (en) | 2014-09-12 | 2016-03-17 | Genentech, Inc. | Anthracycline disulfide intermediates, antibody-drug conjugates and methods |
WO2016040856A2 (en) | 2014-09-12 | 2016-03-17 | Genentech, Inc. | Cysteine engineered antibodies and conjugates |
WO2016037644A1 (en) | 2014-09-10 | 2016-03-17 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
WO2016090050A1 (en) | 2014-12-03 | 2016-06-09 | Genentech, Inc. | Quaternary amine compounds and antibody-drug conjugates thereof |
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- 2003-02-21 DE DE60334364T patent/DE60334364D1/en not_active Expired - Lifetime
- 2003-02-21 CA CA002475509A patent/CA2475509A1/en not_active Abandoned
- 2003-02-21 AU AU2003224624A patent/AU2003224624B2/en not_active Ceased
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Title |
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LEONARD J P ET AL.: "BLOOD", vol. 94, 15 November 1999, W.B. SAUNDERS, article "EPRATUZUMAB, A NEW ANTI-CD22, HUMANIZED, MONOCLONAL ANTIBODY FOR THE THERAPY OF NON-HODGKIN'S LYMPHOMA and PHASE I/II TRIAL RESULTS", pages: 92A - 93A |
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AU2003224624A1 (en) | 2003-09-09 |
US20120301472A1 (en) | 2012-11-29 |
WO2003072736A3 (en) | 2003-12-04 |
JP2009221224A (en) | 2009-10-01 |
AU2003224624B2 (en) | 2008-08-28 |
US20030202975A1 (en) | 2003-10-30 |
EP1485130A4 (en) | 2006-11-22 |
JP2005526044A (en) | 2005-09-02 |
US8734792B2 (en) | 2014-05-27 |
EP1476120B1 (en) | 2010-09-29 |
CA2476776A1 (en) | 2003-09-04 |
DE60334364D1 (en) | 2010-11-11 |
CN1646161A (en) | 2005-07-27 |
US20080118505A1 (en) | 2008-05-22 |
WO2003072736A2 (en) | 2003-09-04 |
JP2005526501A (en) | 2005-09-08 |
EP1476120A2 (en) | 2004-11-17 |
AU2003215365A1 (en) | 2003-09-09 |
US20040001828A1 (en) | 2004-01-01 |
US20070264260A1 (en) | 2007-11-15 |
EP1476120A4 (en) | 2005-12-28 |
KR20040094705A (en) | 2004-11-10 |
ATE482719T1 (en) | 2010-10-15 |
CA2475509A1 (en) | 2003-09-04 |
WO2003072036A3 (en) | 2003-12-31 |
EP1485130A2 (en) | 2004-12-15 |
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