WO2003087759A3 - Non-invasive spectroscopic measurement of analytes using a matched reference analyte - Google Patents

Non-invasive spectroscopic measurement of analytes using a matched reference analyte Download PDF

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Publication number
WO2003087759A3
WO2003087759A3 PCT/US2003/010484 US0310484W WO03087759A3 WO 2003087759 A3 WO2003087759 A3 WO 2003087759A3 US 0310484 W US0310484 W US 0310484W WO 03087759 A3 WO03087759 A3 WO 03087759A3
Authority
WO
WIPO (PCT)
Prior art keywords
analyte
matched reference
spectroscopic measurement
attribute
analytes
Prior art date
Application number
PCT/US2003/010484
Other languages
French (fr)
Other versions
WO2003087759A2 (en
Inventor
Mark Ries Robinson
Cliona Fleming
Howland Jones
Mark Rohrscheib
Original Assignee
Inlight Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inlight Solutions Inc filed Critical Inlight Solutions Inc
Priority to AU2003224847A priority Critical patent/AU2003224847A1/en
Priority to EP03721541A priority patent/EP1542581A4/en
Publication of WO2003087759A2 publication Critical patent/WO2003087759A2/en
Publication of WO2003087759A3 publication Critical patent/WO2003087759A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1495—Calibrating or testing of in-vivo probes

Abstract

A method is provided for building improved calibration models or for improving modifications to these models or validation of the models used in the non-invasive spectroscopic measurement of an analyte or attribute of tissue. The method uses a matched reference sample and measurement of that sample to ensure that the correct relationship between the spectra and analyte is made during the model building, modification or calibration process. A matched reference sample is one in which the analyte of interest or attribute of interest in the reference sample is representative of the analyte or attribute at the site being non-invasively sampled or the agreement between the reference concentration and the non-invasively sampled concentration is clinically significant.
PCT/US2003/010484 2002-04-04 2003-04-04 Non-invasive spectroscopic measurement of analytes using a matched reference analyte WO2003087759A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2003224847A AU2003224847A1 (en) 2002-04-04 2003-04-04 Non-invasive spectroscopic measurement of analytes using a matched reference analyte
EP03721541A EP1542581A4 (en) 2002-04-04 2003-04-04 Non-invasive spectroscopic measurement of analytes using a matched reference analyte

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/116,269 US7027848B2 (en) 2002-04-04 2002-04-04 Apparatus and method for non-invasive spectroscopic measurement of analytes in tissue using a matched reference analyte
US10/116,269 2002-04-04

Publications (2)

Publication Number Publication Date
WO2003087759A2 WO2003087759A2 (en) 2003-10-23
WO2003087759A3 true WO2003087759A3 (en) 2004-04-01

Family

ID=28673934

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/010484 WO2003087759A2 (en) 2002-04-04 2003-04-04 Non-invasive spectroscopic measurement of analytes using a matched reference analyte

Country Status (4)

Country Link
US (1) US7027848B2 (en)
EP (1) EP1542581A4 (en)
AU (1) AU2003224847A1 (en)
WO (1) WO2003087759A2 (en)

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