WO2003095457A1 - Adenosine a3 receptor modulators - Google Patents
Adenosine a3 receptor modulators Download PDFInfo
- Publication number
- WO2003095457A1 WO2003095457A1 PCT/US2002/014191 US0214191W WO03095457A1 WO 2003095457 A1 WO2003095457 A1 WO 2003095457A1 US 0214191 W US0214191 W US 0214191W WO 03095457 A1 WO03095457 A1 WO 03095457A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- substituted
- compound
- amino
- alkyl
- triazolo
- Prior art date
Links
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Abstract
Description
Claims
Priority Applications (7)
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JP2004503471A JP2006510574A (en) | 2002-04-26 | 2002-05-06 | Adenosine A3 receptor modulator |
IL15959402A IL159594A0 (en) | 2002-04-26 | 2002-05-06 | Adenosine a3 receptor modulators |
MXPA03011958A MXPA03011958A (en) | 2002-04-26 | 2002-05-06 | Adenosine a3. |
CA002451081A CA2451081A1 (en) | 2002-04-26 | 2002-05-06 | Adenosine a<sb>3</sb> receptor modulators |
BR0210720-1A BR0210720A (en) | 2002-04-26 | 2002-05-06 | Compound and use thereof |
EP02734202A EP1499614A4 (en) | 2002-04-26 | 2002-05-06 | Adenosine a3 receptor modulators |
AU2002305386A AU2002305386A1 (en) | 2002-04-26 | 2002-05-06 | Adenosine a3 receptor modulators |
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US10/134,219 US6921825B2 (en) | 1998-09-16 | 2002-04-26 | Adenosine A3 receptor modulators |
US10/134,219 | 2002-04-26 |
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WO2003095457A1 true WO2003095457A1 (en) | 2003-11-20 |
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EP (1) | EP1499614A4 (en) |
JP (1) | JP2006510574A (en) |
AU (1) | AU2002305386A1 (en) |
BR (1) | BR0210720A (en) |
CA (1) | CA2451081A1 (en) |
IL (1) | IL159594A0 (en) |
MX (1) | MXPA03011958A (en) |
WO (1) | WO2003095457A1 (en) |
ZA (1) | ZA200309907B (en) |
Cited By (9)
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EP1766060A1 (en) * | 2004-05-14 | 2007-03-28 | King Pharmaceuticals Research and Development Inc. | Methods of diagnosing and prognosticating solid tumors and melanoma |
JP2007514758A (en) * | 2003-12-19 | 2007-06-07 | シェーリング コーポレイション | Pharmaceutical composition |
EP1798233A1 (en) * | 2005-12-19 | 2007-06-20 | Faust Pharmaceuticals | Pyrrolo[1,2-a]quinoxaline derivatives as Adenosine A3 receptor modulators and uses thereof |
CN101056859B (en) * | 2004-11-15 | 2010-05-05 | 塞诺菲-安万特股份有限公司 | Quinoline derivatives as isotope labeling for adenosine a3 receptor ligand |
US20130190335A1 (en) * | 2012-01-25 | 2013-07-25 | The United State of America, as represented by the Secretary, Department of Health and Human Service | Fluorescent antagonists of the a3 adenosine receptor |
WO2016202935A1 (en) * | 2015-06-19 | 2016-12-22 | Bayer Pharma Aktiengesellschaft | Glucose transport inhibitors |
CN111004245A (en) * | 2019-12-11 | 2020-04-14 | 徐州医科大学 | Pyrazole-pyrimido imidazole compound, preparation method and application thereof |
US10995101B2 (en) | 2017-03-30 | 2021-05-04 | Iteos Therapeutics Sa | 2-oxo-thiazole derivatives as A2A inhibitors and compounds for use in the treatment of cancers |
US11376255B2 (en) | 2018-09-11 | 2022-07-05 | iTeos Belgium SA | Thiocarbamate derivatives as A2A inhibitors, pharmaceutical composition thereof and combinations with anticancer agents |
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KR20050044593A (en) * | 2001-11-30 | 2005-05-12 | 쉐링 코포레이션 | Adenosine a2a receptor antagonists |
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US20090088403A1 (en) * | 2007-05-07 | 2009-04-02 | Randy Blakely | A3 adenosine receptors as targets for the modulation of central serotonergic signaling |
US8871751B2 (en) * | 2008-01-18 | 2014-10-28 | The Board Of Trustees Of The University Of Illinois | Compositions and methods relating to nuclear hormone and steroid hormone receptors including inhibitors of estrogen receptor alpha-mediated gene expression and inhibition of breast cancer |
US20100021540A1 (en) * | 2008-02-28 | 2010-01-28 | Abbott Laboratories | Tablets and Preparation Thereof |
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US8916570B2 (en) | 2008-03-31 | 2014-12-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | A3 adenosine receptor agonists and antagonists |
US20110190324A1 (en) * | 2008-07-16 | 2011-08-04 | Edward Leung | Methods of treating atherosclerosis |
US9181253B2 (en) | 2008-08-01 | 2015-11-10 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Adenosine receptor agonists, partial agonists, and antagonists |
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- 2002-05-06 CA CA002451081A patent/CA2451081A1/en not_active Abandoned
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- 2002-05-06 AU AU2002305386A patent/AU2002305386A1/en not_active Abandoned
- 2002-05-06 JP JP2004503471A patent/JP2006510574A/en not_active Withdrawn
- 2002-05-06 EP EP02734202A patent/EP1499614A4/en not_active Withdrawn
- 2002-05-06 MX MXPA03011958A patent/MXPA03011958A/en active IP Right Grant
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2005
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2007
- 2007-07-09 US US11/774,784 patent/US7470698B2/en not_active Expired - Fee Related
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JP2007514758A (en) * | 2003-12-19 | 2007-06-07 | シェーリング コーポレイション | Pharmaceutical composition |
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US20130190335A1 (en) * | 2012-01-25 | 2013-07-25 | The United State of America, as represented by the Secretary, Department of Health and Human Service | Fluorescent antagonists of the a3 adenosine receptor |
US9227979B2 (en) * | 2012-01-25 | 2016-01-05 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Fluorescent antagonists of the A3 adenosine receptor |
WO2016202935A1 (en) * | 2015-06-19 | 2016-12-22 | Bayer Pharma Aktiengesellschaft | Glucose transport inhibitors |
US10995101B2 (en) | 2017-03-30 | 2021-05-04 | Iteos Therapeutics Sa | 2-oxo-thiazole derivatives as A2A inhibitors and compounds for use in the treatment of cancers |
US11376255B2 (en) | 2018-09-11 | 2022-07-05 | iTeos Belgium SA | Thiocarbamate derivatives as A2A inhibitors, pharmaceutical composition thereof and combinations with anticancer agents |
CN111004245A (en) * | 2019-12-11 | 2020-04-14 | 徐州医科大学 | Pyrazole-pyrimido imidazole compound, preparation method and application thereof |
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Publication number | Publication date |
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AU2002305386A1 (en) | 2003-11-11 |
US20060040959A1 (en) | 2006-02-23 |
JP2006510574A (en) | 2006-03-30 |
US7470698B2 (en) | 2008-12-30 |
EP1499614A1 (en) | 2005-01-26 |
EP1499614A4 (en) | 2005-08-24 |
US6921825B2 (en) | 2005-07-26 |
BR0210720A (en) | 2004-07-20 |
US20030144266A1 (en) | 2003-07-31 |
MXPA03011958A (en) | 2005-06-06 |
US20070249641A1 (en) | 2007-10-25 |
IL159594A0 (en) | 2004-06-01 |
CA2451081A1 (en) | 2003-11-20 |
ZA200309907B (en) | 2005-03-22 |
US7271171B2 (en) | 2007-09-18 |
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