WO2003103563A3 - Powder inhaler - Google Patents

Powder inhaler Download PDF

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Publication number
WO2003103563A3
WO2003103563A3 PCT/IN2003/000215 IN0300215W WO03103563A3 WO 2003103563 A3 WO2003103563 A3 WO 2003103563A3 IN 0300215 W IN0300215 W IN 0300215W WO 03103563 A3 WO03103563 A3 WO 03103563A3
Authority
WO
WIPO (PCT)
Prior art keywords
medicament containing
containing recess
powder inhaler
air inlet
air
Prior art date
Application number
PCT/IN2003/000215
Other languages
French (fr)
Other versions
WO2003103563A2 (en
Inventor
Satish Gokhale
Subhas Balaram Bhowmick
Kirti Wardhaman Ganorkar
Ashwin Bhujanga Rao
Original Assignee
Sun Pharmaceutical Ind Ltd
Satish Gokhale
Subhas Balaram Bhowmick
Kirti Wardhaman Ganorkar
Ashwin Bhujanga Rao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharmaceutical Ind Ltd, Satish Gokhale, Subhas Balaram Bhowmick, Kirti Wardhaman Ganorkar, Ashwin Bhujanga Rao filed Critical Sun Pharmaceutical Ind Ltd
Priority to AU2003267809A priority Critical patent/AU2003267809A1/en
Publication of WO2003103563A2 publication Critical patent/WO2003103563A2/en
Publication of WO2003103563A3 publication Critical patent/WO2003103563A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043Non-destructive separation of the package, e.g. peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0031Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up by bursting or breaking the package, i.e. without cutting or piercing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52Details
    • B65D75/58Opening or contents-removing devices added or incorporated during package manufacture
    • B65D75/5816Opening or contents-removing devices added or incorporated during package manufacture for tearing a corner or other small portion next to the edge, e.g. a U-shaped portion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • A61M11/003Particle size control by passing the aerosol trough sieves or filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/07General characteristics of the apparatus having air pumping means
    • A61M2205/071General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/075Bulb type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/43General characteristics of the apparatus making noise when used correctly
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8218Gas operated
    • A61M2205/8225Gas operated using incorporated gas cartridges for the driving gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/14Static flow deviators in tubes disturbing laminar flow in tubes, e.g. archimedes screws
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/16Rotating swirling helical flow, e.g. by tangential inflows

Abstract

The present invention provides a powder inhaler (10) for administration of a unit dose of a medicament (36), said powder inhaler comprising: (A) Walls (14, 16) enclosing at least one chamber (12) comprising a medicament containing recess at one end and a channel extending from the medicament containing recess to the air outlet hole (34); (B) Air inlet hole(s) (24) located near the medicament containing recess; (C) An air outlet hole (34); and (D) Means (20, 21, 32) for sealing said air inlet (24) and outlet holes (34), wherein the location of the air inlet hole(s) (24) with respect to the medicament containing recess is such that upon inspiration by the patient, the air stream directly impacts the powder bed, entrains the particles and carries them to the air outlet (34) for inspiration by the patient.
PCT/IN2003/000215 2002-06-07 2003-06-06 Powder inhaler WO2003103563A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003267809A AU2003267809A1 (en) 2002-06-07 2003-06-06 Powder inhaler

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN509/MUM/2002 2002-06-07
IN509MU2002 2002-06-07

Publications (2)

Publication Number Publication Date
WO2003103563A2 WO2003103563A2 (en) 2003-12-18
WO2003103563A3 true WO2003103563A3 (en) 2004-07-15

Family

ID=29727207

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2003/000215 WO2003103563A2 (en) 2002-06-07 2003-06-06 Powder inhaler

Country Status (2)

Country Link
AU (1) AU2003267809A1 (en)
WO (1) WO2003103563A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0700839D0 (en) * 2007-01-17 2007-02-21 Braithwaite Philip Device
WO2009082343A1 (en) 2007-12-20 2009-07-02 Astrazeneca Ab Dispenser and method for entraining powder in an airflow 537
BRPI0907713A2 (en) 2008-02-12 2015-07-21 Astrazeneca Ab Inhaler comprising a base having a plurality of drug-containing sealed cavities
WO2009102274A1 (en) * 2008-02-12 2009-08-20 Astrazeneca Ab Inhaler comprising a base having at least one sealed cavity containing medicament
US8397718B2 (en) 2008-02-12 2013-03-19 Astrazeneca Ab Inhaler comprising a base having at least one sealed cavity containing medicament
GB0910537D0 (en) 2009-06-18 2009-07-29 Ivax Pharmaceuticals Ireland Inhaler
JP2012531961A (en) 2009-07-01 2012-12-13 アストラゼネカ・アクチエボラーグ Dispenser and method for drawing powder into an air stream
WO2013036881A2 (en) 2011-09-07 2013-03-14 Syphase, Llc Dry powder inhalation device
SE1300485A1 (en) * 2013-04-23 2014-10-24 Simplified Solutions Sweden Ab Disposable inhaler for powders
SE538667C2 (en) * 2013-12-23 2016-10-11 Iconovo Ab Enkeldostorrpulverinhalator
EP3104824B1 (en) 2014-02-12 2019-10-09 Sanofi-Aventis Deutschland GmbH Compressible container with an opaque cover for a liquid medicament
EP3160557B1 (en) * 2014-06-27 2020-08-12 Belforti, Sergio A powder inhaler device
WO2016014153A1 (en) * 2014-07-23 2016-01-28 Microdose Therapeutx, Inc. Dry powder nebulizer
WO2018183528A1 (en) 2017-03-28 2018-10-04 Concentrx Pharmaceuticals, Inc. Devices and methods for delivering dry powder medicaments
EP4204048A1 (en) 2020-08-25 2023-07-05 Vectura Delivery Devices Limited Unit dose dry powder inhaler
CA3214327A1 (en) 2021-05-07 2022-11-10 Andreas Meliniotis Unit dose dry powder inhaler

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5239991A (en) * 1989-06-21 1993-08-31 Fisons Plc Disposable powder medicament inhalation device with peel-off cover
US5533505A (en) * 1992-03-04 1996-07-09 Astra Aktiebolag Disposable inhaler
USD441859S1 (en) * 1999-04-06 2001-05-08 Istituto Biochimico Pavese Pharma S.P.A. Disposable dry-powder inhaler
WO2002013897A2 (en) * 2000-08-14 2002-02-21 Advanced Inhalation Research, Inc. Inhalation device and method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5239991A (en) * 1989-06-21 1993-08-31 Fisons Plc Disposable powder medicament inhalation device with peel-off cover
US5533505A (en) * 1992-03-04 1996-07-09 Astra Aktiebolag Disposable inhaler
USD441859S1 (en) * 1999-04-06 2001-05-08 Istituto Biochimico Pavese Pharma S.P.A. Disposable dry-powder inhaler
WO2002013897A2 (en) * 2000-08-14 2002-02-21 Advanced Inhalation Research, Inc. Inhalation device and method

Also Published As

Publication number Publication date
AU2003267809A1 (en) 2003-12-22
AU2003267809A8 (en) 2003-12-22
WO2003103563A2 (en) 2003-12-18

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