WO2004006840A3 - Three dimensional cell patterned bioploymer scaffolds and method of making the same - Google Patents
Three dimensional cell patterned bioploymer scaffolds and method of making the same Download PDFInfo
- Publication number
- WO2004006840A3 WO2004006840A3 PCT/US2003/021782 US0321782W WO2004006840A3 WO 2004006840 A3 WO2004006840 A3 WO 2004006840A3 US 0321782 W US0321782 W US 0321782W WO 2004006840 A3 WO2004006840 A3 WO 2004006840A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- scaffolds
- bioploymer
- patterned
- making
- same
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5067—Liver cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03F—PHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR
- G03F7/00—Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printing surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003251874A AU2003251874A1 (en) | 2002-07-12 | 2003-07-14 | Three dimensional cell patterned bioploymer scaffolds and method of making the same |
US11/035,394 US8906684B2 (en) | 2002-07-12 | 2005-01-12 | Three dimensional cell patterned biopolymer scaffolds and methods of making the same |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39587202P | 2002-07-12 | 2002-07-12 | |
US60/395,872 | 2002-07-12 | ||
US40185402P | 2002-08-07 | 2002-08-07 | |
US60/401,854 | 2002-08-07 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/035,394 Continuation-In-Part US8906684B2 (en) | 2002-07-12 | 2005-01-12 | Three dimensional cell patterned biopolymer scaffolds and methods of making the same |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004006840A2 WO2004006840A2 (en) | 2004-01-22 |
WO2004006840A3 true WO2004006840A3 (en) | 2004-04-08 |
Family
ID=30118553
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/021782 WO2004006840A2 (en) | 2002-07-12 | 2003-07-14 | Three dimensional cell patterned bioploymer scaffolds and method of making the same |
Country Status (3)
Country | Link |
---|---|
US (1) | US8906684B2 (en) |
AU (1) | AU2003251874A1 (en) |
WO (1) | WO2004006840A2 (en) |
Families Citing this family (104)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7759113B2 (en) * | 1999-04-30 | 2010-07-20 | The General Hospital Corporation | Fabrication of tissue lamina using microfabricated two-dimensional molds |
US7776021B2 (en) * | 2000-04-28 | 2010-08-17 | The Charles Stark Draper Laboratory | Micromachined bilayer unit for filtration of small molecules |
US20060270032A1 (en) * | 2005-05-24 | 2006-11-30 | The Regents Of The University Of California | Microscale micropatterened engineered in vitro tissue |
US20050019747A1 (en) * | 2002-08-07 | 2005-01-27 | Anderson Daniel G. | Nanoliter-scale synthesis of arrayed biomaterials and screening thereof |
US20040028804A1 (en) * | 2002-08-07 | 2004-02-12 | Anderson Daniel G. | Production of polymeric microarrays |
EP1589814B1 (en) * | 2003-01-16 | 2009-08-12 | The General Hospital Corporation | Use of three-dimensional microfabricated tissue engineered systems for pharmacologic applications |
US7960166B2 (en) | 2003-05-21 | 2011-06-14 | The General Hospital Corporation | Microfabricated compositions and processes for engineering tissues containing multiple cell types |
US8241905B2 (en) | 2004-02-24 | 2012-08-14 | The Curators Of The University Of Missouri | Self-assembling cell aggregates and methods of making engineered tissue using the same |
GB0411348D0 (en) * | 2004-05-21 | 2004-06-23 | Univ Cranfield | Fabrication of polymeric structures using laser initiated polymerisation |
US7556490B2 (en) * | 2004-07-30 | 2009-07-07 | Board Of Regents, The University Of Texas System | Multi-material stereolithography |
US7658603B2 (en) | 2005-03-31 | 2010-02-09 | Board Of Regents, The University Of Texas System | Methods and systems for integrating fluid dispensing technology with stereolithography |
US7780897B2 (en) * | 2005-04-22 | 2010-08-24 | Board Of Regents, The University Of Texas System | Hydrogel constructs using stereolithography |
US9637715B2 (en) | 2005-07-07 | 2017-05-02 | Emd Millipore Corporation | Cell culture and invasion assay method and system |
US9376658B2 (en) | 2008-01-03 | 2016-06-28 | Emd Millipore Corporation | Cell culture array system for automated assays and methods of operation and manufacture thereof |
US9354156B2 (en) | 2007-02-08 | 2016-05-31 | Emd Millipore Corporation | Microfluidic particle analysis method, device and system |
US9388374B2 (en) | 2005-07-07 | 2016-07-12 | Emd Millipore Corporation | Microfluidic cell culture systems |
ES2865180T3 (en) | 2005-07-07 | 2021-10-15 | Univ California | Apparatus for cell culture formation |
US8257964B2 (en) | 2006-01-04 | 2012-09-04 | Cell ASIC | Microwell cell-culture device and fabrication method |
US7745209B2 (en) | 2005-07-26 | 2010-06-29 | Corning Incorporated | Multilayered cell culture apparatus |
JP5039715B2 (en) * | 2006-01-24 | 2012-10-03 | ブラウン ユニバーシティ | Cell aggregation and encapsulation devices and methods |
US7718351B2 (en) * | 2006-03-14 | 2010-05-18 | Agency For Science, Technology & Research | Three-dimensional fabrication of biocompatible structures in anatomical shapes and dimensions for tissue engineering and organ replacement |
US20080108138A1 (en) * | 2006-06-13 | 2008-05-08 | Vermette Patrick | Bioactive compositions and their use in cell patterning |
US7745210B2 (en) * | 2006-06-30 | 2010-06-29 | Corning Incorporated | Fluid flow diverter for cell culture vessel |
US20100215720A1 (en) | 2006-08-08 | 2010-08-26 | Fundacion Inasmet | Implantable optical system, method for developing it and applications |
US20080193536A1 (en) * | 2006-08-14 | 2008-08-14 | Alireza Khademhosseini | Cell-Laden Hydrogels |
CN101578520B (en) | 2006-10-18 | 2015-09-16 | 哈佛学院院长等 | Based on formed pattern porous medium cross flow and through biometric apparatus, and preparation method thereof and using method |
US8529835B2 (en) | 2006-11-03 | 2013-09-10 | Tufts University | Biopolymer sensor and method of manufacturing the same |
EP2086749B1 (en) | 2006-11-03 | 2013-05-08 | Trustees Of Tufts College | Nanopatterned biopolymer optical device and method of manufacturing the same |
JP2010508852A (en) | 2006-11-03 | 2010-03-25 | トラスティーズ オブ タフツ カレッジ | Electroactive biopolymer optical device, electroactive biopolymer electrooptical device and method for producing the same |
WO2008118211A2 (en) * | 2006-11-03 | 2008-10-02 | Trustees Of Tufts College | Biopolymer photonic crystals and method of manufacturing the same |
US7897379B2 (en) * | 2007-02-26 | 2011-03-01 | Corning Incorporated | Device and method for reducing bubble formation in cell culture |
US9309491B2 (en) * | 2007-05-29 | 2016-04-12 | Corning Incorporated | Cell culture apparatus for co-culture of cells |
WO2009043052A1 (en) * | 2007-09-27 | 2009-04-02 | Columbia University | Methods and systems for forming biocompatible materials |
EP2265959B1 (en) * | 2008-03-27 | 2014-03-05 | President and Fellows of Harvard College | Paper-based cellular arrays |
CN102016594B (en) * | 2008-03-27 | 2014-04-23 | 哈佛学院院长等 | Cotton thread as a low-cost multi-assay diagnostic platform |
CN102016596B (en) * | 2008-03-27 | 2014-09-17 | 哈佛学院院长等 | Paper-based microfluidic systems |
EP2257819A4 (en) | 2008-03-27 | 2017-10-11 | President and Fellows of Harvard College | Three-dimensional microfluidic devices |
US9121847B2 (en) * | 2008-04-08 | 2015-09-01 | Massachussetts Institute Of Technology | Three-dimensional microfluidic platforms and methods of use thereof |
US8876513B2 (en) * | 2008-04-25 | 2014-11-04 | 3D Systems, Inc. | Selective deposition modeling using CW UV LED curing |
WO2009134768A1 (en) * | 2008-05-01 | 2009-11-05 | Massachusetts Institute Of Technology (Mit) | Devices and processes for analyzing nucleic acid damage and repair using electrophoresis |
AU2009271223B2 (en) | 2008-06-24 | 2013-05-16 | The Curators Of The University Of Missouri | Self-assembling multicellular bodies and methods of producing a three-dimensional biological structure using the same |
KR102481683B1 (en) | 2008-07-16 | 2022-12-28 | 칠드런'즈 메디컬 센터 코포레이션 | Organ mimic device with microchannels and methods of use and manufacturing thereof |
US8293696B2 (en) * | 2009-02-06 | 2012-10-23 | Ecolab, Inc. | Alkaline composition comprising a chelant mixture, including HEIDA, and method of producing same |
US9192933B2 (en) | 2009-03-06 | 2015-11-24 | President And Fellows Of Harvard College | Microfluidic, electrochemical devices |
US8501476B2 (en) * | 2009-10-07 | 2013-08-06 | Brown University | Assays and methods for fusing cell aggregates to form proto-tissues |
US9353342B2 (en) | 2010-01-21 | 2016-05-31 | Emd Millipore Corporation | Cell culture and gradient migration assay methods and devices |
CA2788113A1 (en) | 2010-02-03 | 2011-08-11 | President And Fellows Of Harvard College | Devices and methods for multiplexed assays |
DE102010038155A1 (en) * | 2010-10-05 | 2012-04-05 | Technische Universität Ilmenau | A structure simulated to a biological tissue and process for its preparation |
EP2629975B1 (en) | 2010-10-21 | 2022-03-09 | Organovo, Inc. | Devices for the fabrication of tissue |
WO2012116363A2 (en) * | 2011-02-25 | 2012-08-30 | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, a body corporate and politic | Biomolecular patterning of three dimensional tissue scaffolds |
DK2681306T3 (en) | 2011-02-28 | 2019-04-23 | Harvard College | CELL CULTURE SYSTEM |
US10526572B2 (en) | 2011-04-01 | 2020-01-07 | EMD Millipore Corporaticn | Cell culture and invasion assay method and system |
US20140093690A1 (en) * | 2011-05-31 | 2014-04-03 | Nanoptics, Incorporated | Method and apparatus for lithographic manufacture of multi-component polymeric fiber plates |
US20140160467A1 (en) * | 2011-08-18 | 2014-06-12 | Newport Corporation | System and method for characterizing material shrinkage using coherent anti-stokes raman scattering (cars) microscopy |
US9243278B2 (en) | 2011-09-22 | 2016-01-26 | Brown University | Mechanotransduction by the synergistic action of heterotypic cell interactions |
US9468680B2 (en) | 2011-09-22 | 2016-10-18 | Brown University | Differential effects of drugs on transport in a multi-layer 3D spheroid model |
CN104245917B (en) | 2011-12-03 | 2017-07-21 | Emd密理博公司 | Miniature culture system and method for Microfluidic cell culture |
US9725687B2 (en) | 2011-12-09 | 2017-08-08 | President And Fellows Of Harvard College | Integrated human organ-on-chip microphysiological systems |
EP2641965A1 (en) * | 2012-03-21 | 2013-09-25 | Parc Científic Barcelona | Method for manufacturing a three-dimensional biomimetic scaffold and uses thereof |
US9499779B2 (en) | 2012-04-20 | 2016-11-22 | Organovo, Inc. | Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking |
US9878137B2 (en) | 2012-05-30 | 2018-01-30 | The Regents Of The University Of California | Bioactive agent delivery devices and methods of making and using the same |
WO2014011775A1 (en) * | 2012-07-10 | 2014-01-16 | The Trustees Of The University Of Pennsylvania | Biomaterials for enhanced implant-host integration |
US9442105B2 (en) | 2013-03-15 | 2016-09-13 | Organovo, Inc. | Engineered liver tissues, arrays thereof, and methods of making the same |
WO2014197622A2 (en) * | 2013-06-04 | 2014-12-11 | The Regents Of The University Of California | Liver-mimetic device and method for simulation of hepatic function using such device |
JP6349638B2 (en) * | 2013-07-16 | 2018-07-04 | 大日本印刷株式会社 | Method for producing cell culture substrate |
EP3024582A4 (en) | 2013-07-22 | 2017-03-08 | President and Fellows of Harvard College | Microfluidic cartridge assembly |
DK3028042T3 (en) | 2013-07-31 | 2021-10-04 | Organovo Inc | AUTOMATED DEVICES, SYSTEMS AND METHODS OF PROCESSING |
KR101450749B1 (en) * | 2013-10-29 | 2014-10-17 | 서강대학교산학협력단 | Method of manufacturing micro-cantilever |
CA2934662C (en) | 2013-12-20 | 2024-02-20 | President And Fellows Of Harvard College | Low shear microfluidic devices and methods of use and manufacturing thereof |
JP6608382B2 (en) | 2014-02-26 | 2019-11-20 | ルマ セラピューティクス,インク. | Ultraviolet light treatment apparatus and method |
US20150248060A1 (en) * | 2014-02-28 | 2015-09-03 | Konica Minolta Laboratory U.S.A., Inc. | Method of making thermal insulation film and thermal insulation film product |
CA3177480A1 (en) | 2014-04-04 | 2015-10-08 | Organovo, Inc. | Engineered three-dimensional breast tissue, adipose tissue, and tumor disease model |
GB2546424A (en) | 2014-07-14 | 2017-07-19 | Harvard College | Systems and methods for improved performance of fluidic and microfluidic systems |
SG11201701540PA (en) * | 2014-08-28 | 2017-03-30 | Stemonix Inc | Method of fabricating cell arrays and uses thereof |
US10351819B2 (en) | 2014-09-16 | 2019-07-16 | The Regents Of The University Of California | Method for fabrication of microwells for controlled formation of 3-dimensional multicellular-shapes |
WO2016057571A1 (en) | 2014-10-06 | 2016-04-14 | Organovo, Inc. | Engineered renal tissues, arrays thereof, and methods of making the same |
US20160122723A1 (en) | 2014-11-05 | 2016-05-05 | Organovo, Inc. | Engineered three-dimensional skin tissues, arrays thereof, and methods of making the same |
US10059990B2 (en) | 2015-04-14 | 2018-08-28 | Massachusetts Institute Of Technology | In situ nucleic acid sequencing of expanded biological samples |
US11408890B2 (en) | 2015-04-14 | 2022-08-09 | Massachusetts Institute Of Technology | Iterative expansion microscopy |
US10526649B2 (en) | 2015-04-14 | 2020-01-07 | Massachusetts Institute Of Technology | Augmenting in situ nucleic acid sequencing of expanded biological samples with in vitro sequence information |
KR101907337B1 (en) * | 2015-04-29 | 2018-10-11 | 쓰리엠 이노베이티브 프로퍼티즈 캄파니 | Swellable Film Forming Composition and Method of Nanoimprint Lithography Using It |
US11248212B2 (en) | 2015-06-30 | 2022-02-15 | StemoniX Inc. | Surface energy directed cell self assembly |
WO2017019542A1 (en) | 2015-07-24 | 2017-02-02 | President And Fellows Of Harvard College | Radial microfluidic devices and methods of use |
CN108139408B (en) | 2015-08-07 | 2020-08-28 | 麻省理工学院 | Protein retention expansion microscopy |
WO2017040156A1 (en) * | 2015-09-01 | 2017-03-09 | The Board Trustees Of The Leland Stanford Junior University | Systems and methods for additive manufacturing of hybrid multi-material constructs and constructs made therefrom |
US11214661B2 (en) | 2015-09-17 | 2022-01-04 | Massachusetts Institute Of Technology | Three-dimensional nanofabrication by patterning of hydrogels |
US11338065B2 (en) | 2015-10-08 | 2022-05-24 | Massachusetts Institute Of Technology | In situ expansion of engineered devices for regeneration |
JP2018537073A (en) | 2015-10-15 | 2018-12-20 | ステモニックス インコーポレイティド | Method for producing cells using hollow fiber bioreactor |
CN109310527A (en) | 2016-02-09 | 2019-02-05 | 鲁玛治疗公司 | For treating psoriasic method, composition and equipment by light therapy |
WO2018009943A2 (en) | 2016-07-08 | 2018-01-11 | Cypre, Inc. | Apparatus for patterning hydrogels into multi-well plates |
US10995361B2 (en) | 2017-01-23 | 2021-05-04 | Massachusetts Institute Of Technology | Multiplexed signal amplified FISH via splinted ligation amplification and sequencing |
WO2018157048A1 (en) | 2017-02-24 | 2018-08-30 | Massachusetts Institute Of Technology | Methods for examining podocyte foot processes in human renal samples using conventional optical microscopy |
JP6380962B1 (en) * | 2017-03-15 | 2018-08-29 | 国立大学法人東北大学 | Electrochemical production method of hydrogel, production method of hydrogel in which cells are patterned, hydrogel production device and transducer |
US10940475B2 (en) * | 2017-03-30 | 2021-03-09 | Purdue Research Foundation | Gradient-on-a-chip |
WO2019023214A1 (en) | 2017-07-25 | 2019-01-31 | Massachusetts Institute Of Technology | In situ atac sequencing |
WO2019103970A2 (en) | 2017-11-21 | 2019-05-31 | Cypre, Inc. | Mask for generating features in a microwell plate |
US11873374B2 (en) | 2018-02-06 | 2024-01-16 | Massachusetts Institute Of Technology | Swellable and structurally homogenous hydrogels and methods of use thereof |
CA3120576A1 (en) | 2018-11-26 | 2020-06-04 | Massachusetts Institute Of Technology | Compositions and methods for immune tolerance |
US11346842B2 (en) | 2019-06-20 | 2022-05-31 | Massachusetts Institute Of Technology | Single molecule peptide sequencing methods |
WO2021113505A1 (en) | 2019-12-05 | 2021-06-10 | Massachusetts Institute Of Technology | Method for preparing a specimen for expansion microscopy |
US20230272327A1 (en) * | 2020-07-02 | 2023-08-31 | University Of Florida Research Foundation, Inc. | Perfusion-enabled bioreactor |
AU2022205377A1 (en) | 2021-01-08 | 2023-07-20 | Cellanome, Inc. | Devices and methods for analyzing biological samples |
US20220373462A1 (en) * | 2021-05-14 | 2022-11-24 | MBD Co., Ltd. | Measuring method of cell migration using the rate of cell invasion |
DE102022108006A1 (en) | 2022-04-04 | 2023-10-05 | Technische Universität Ilmenau, Körperschaft des öffentlichen Rechts | Replica and method for three-dimensional replication of a biological tissue |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6197575B1 (en) * | 1998-03-18 | 2001-03-06 | Massachusetts Institute Of Technology | Vascularized perfused microtissue/micro-organ arrays |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5266480A (en) * | 1986-04-18 | 1993-11-30 | Advanced Tissue Sciences, Inc. | Three-dimensional skin culture system |
SE9101752D0 (en) * | 1991-06-10 | 1991-06-10 | Procordia Ortech Ab | METHOD OF PRODUCING A MICROSTRUCTURE IN A BIORESORBABLE ELEMENT |
US5514378A (en) * | 1993-02-01 | 1996-05-07 | Massachusetts Institute Of Technology | Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures |
US5776748A (en) * | 1993-10-04 | 1998-07-07 | President And Fellows Of Harvard College | Method of formation of microstamped patterns on plates for adhesion of cells and other biological materials, devices and uses therefor |
US5716413A (en) * | 1995-10-11 | 1998-02-10 | Osteobiologics, Inc. | Moldable, hand-shapable biodegradable implant material |
CA2221195A1 (en) * | 1997-11-14 | 1999-05-14 | Chantal E. Holy | Biodegradable polymer matrix |
HU222543B1 (en) * | 1998-02-23 | 2003-08-28 | Massachusetts Institute Of Technology | Biodegradable shape memory polymers |
US6103255A (en) * | 1999-04-16 | 2000-08-15 | Rutgers, The State University | Porous polymer scaffolds for tissue engineering |
US6605453B2 (en) * | 1999-12-01 | 2003-08-12 | The Regents Of The University Of California | Electric-field-assisted fluidic assembly of inorganic and organic materials, molecules and like small things including living cells |
US6835552B2 (en) * | 2000-12-14 | 2004-12-28 | The Regents Of The University Of California | Impedance measurements for detecting pathogens attached to antibodies |
AU2003205241A1 (en) * | 2002-01-22 | 2003-09-02 | The Penn State Research Foundation | Drug candidate screening systems based on micropatterned hydrogels and microfluidic systems |
-
2003
- 2003-07-14 WO PCT/US2003/021782 patent/WO2004006840A2/en not_active Application Discontinuation
- 2003-07-14 AU AU2003251874A patent/AU2003251874A1/en not_active Abandoned
-
2005
- 2005-01-12 US US11/035,394 patent/US8906684B2/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6197575B1 (en) * | 1998-03-18 | 2001-03-06 | Massachusetts Institute Of Technology | Vascularized perfused microtissue/micro-organ arrays |
Also Published As
Publication number | Publication date |
---|---|
AU2003251874A1 (en) | 2004-02-02 |
US20050169962A1 (en) | 2005-08-04 |
AU2003251874A8 (en) | 2004-02-02 |
US8906684B2 (en) | 2014-12-09 |
WO2004006840A2 (en) | 2004-01-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2004006840A3 (en) | Three dimensional cell patterned bioploymer scaffolds and method of making the same | |
EP0936040A3 (en) | High strength porous concrete structure and method of manufacturing the high strength porous concrete structure | |
NO20060738L (en) | Method of making wall element | |
WO2011079580A1 (en) | Ecological greening wall and construction method thereof | |
WO2004053096A3 (en) | Engineering three-dimensional tissue structures using differentiating embryonic stem cells | |
WO2003067251A3 (en) | Device for performing cell assays | |
ATE432063T1 (en) | METHOD FOR PRODUCING DISPERSIONS CONTAINING PHYSIOLOGICALLY ACTIVE SUBSTANCES USING HIGH PRESSURE AND HIGH SHEER FORCE | |
AU2002305871A1 (en) | An aqueous chemical mixture to mitigate water associated problems in concrete pavements | |
NO20024926L (en) | Materials and methods for the biological production of sulfuric acid | |
KR20100057168A (en) | Ocher prefabricated hollow core brick | |
CN202324318U (en) | Concrete heat isolation building block | |
AU2003281068A1 (en) | Plant nucleotide-sugar pyrophosphatase/phosphodiesterase (nppase), method of obtaining same and use of same in the production of assay devices and in the production of transgenic plants | |
ID29376A (en) | PROCESS FOR PRODUCTION OF RESISTANT GAMPING TOWARDS CHEMICALS | |
AU2003207001A1 (en) | Method of generation and management of unique sequences in dna production | |
AU2003258453A1 (en) | Method of making a flat foundation for a floor without substantial excavation and foundation made by said method | |
KR101499110B1 (en) | Method For Simply Forming Pattern On Outer Surface Of Concrete Structure | |
MD2141B2 (en) | Process for manufacture of hollow building stones | |
DE10314368A1 (en) | Manufacture of compaction columns for ground improvement, by connecting ram to depth vibrator and integrating into depth vibrating process | |
CN204960041U (en) | Compound interior wall between two posts | |
ATE403662T1 (en) | CALIX(4)ARENE NUCLEOSIDE AND CALIX(4)ARENE OLIGONUCLEOTIDE HYBRIDS | |
Cresci | Mario Ridolfi–Intorno a Palazzo Spada a Terni | |
Walsh | Building a Proteomics Facility for the New Millennium-lessons Learned and Future Prospects | |
CN202731065U (en) | Aerated concrete building block | |
AU2003219061A1 (en) | Forming element and concrete structural element, and production method therefor | |
Juskevicius | EVOLUTION OF PLANNING AND DEVELOPMENT OF THE CITY OF VILNIUS |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 11035394 Country of ref document: US |
|
122 | Ep: pct application non-entry in european phase | ||
NENP | Non-entry into the national phase |
Ref country code: JP |
|
WWW | Wipo information: withdrawn in national office |
Country of ref document: JP |