WO2004011905A8 - Quality assurance/quality control for electrospray ionization processes - Google Patents

Quality assurance/quality control for electrospray ionization processes

Info

Publication number
WO2004011905A8
WO2004011905A8 PCT/US2003/023507 US0323507W WO2004011905A8 WO 2004011905 A8 WO2004011905 A8 WO 2004011905A8 US 0323507 W US0323507 W US 0323507W WO 2004011905 A8 WO2004011905 A8 WO 2004011905A8
Authority
WO
WIPO (PCT)
Prior art keywords
bioassay
quality
electrospray ionization
model
quality control
Prior art date
Application number
PCT/US2003/023507
Other languages
French (fr)
Other versions
WO2004011905A3 (en
WO2004011905A2 (en
Inventor
Ben Hitt
Peter J Levine
Timothy A Coleman
Original Assignee
Correlogic Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Correlogic Systems Inc filed Critical Correlogic Systems Inc
Priority to AU2003268031A priority Critical patent/AU2003268031A1/en
Publication of WO2004011905A2 publication Critical patent/WO2004011905A2/en
Publication of WO2004011905A8 publication Critical patent/WO2004011905A8/en
Publication of WO2004011905A3 publication Critical patent/WO2004011905A3/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/24Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Abstract

The present invention relates to a method of quality assurance/quality control for high-throughput bioassay processes. The method includes generating a bioassay process model, and then comparing spectral data based on a combination of a biochip and a test serum to the bioassay process model to determine if the test sample and the bioassay process are producing acceptable data. Alternatively, the method may include comparing spectral data based on a combination of serum and diluents used in an electrospray process to the bioassay process model. If the bioassay process and test sample fall within the model, then the spectrum produced may be further analyzed.
PCT/US2003/023507 2002-07-29 2003-07-28 Quality assurance/quality control for electrospray ionization processes WO2004011905A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003268031A AU2003268031A1 (en) 2002-07-29 2003-07-28 Quality assurance/quality control for electrospray ionization processes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39883102P 2002-07-29 2002-07-29
US60/398,831 2002-07-29

Publications (3)

Publication Number Publication Date
WO2004011905A2 WO2004011905A2 (en) 2004-02-05
WO2004011905A8 true WO2004011905A8 (en) 2004-05-21
WO2004011905A3 WO2004011905A3 (en) 2004-07-15

Family

ID=32312442

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US2003/023506 WO2004011904A2 (en) 2002-07-29 2003-07-28 Quality assurance for high-throughput bioassay methods
PCT/US2003/023505 WO2004106887A2 (en) 2002-07-29 2003-07-28 Quality assurance/quality control for high throughput bioassay process
PCT/US2003/023507 WO2004011905A2 (en) 2002-07-29 2003-07-28 Quality assurance/quality control for electrospray ionization processes

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PCT/US2003/023506 WO2004011904A2 (en) 2002-07-29 2003-07-28 Quality assurance for high-throughput bioassay methods
PCT/US2003/023505 WO2004106887A2 (en) 2002-07-29 2003-07-28 Quality assurance/quality control for high throughput bioassay process

Country Status (5)

Country Link
US (5) US7333896B2 (en)
AR (3) AR040711A1 (en)
AU (3) AU2003268031A1 (en)
TW (3) TW200403434A (en)
WO (3) WO2004011904A2 (en)

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Also Published As

Publication number Publication date
AR040713A1 (en) 2005-04-20
WO2004011905A3 (en) 2004-07-15
AU2003261273A1 (en) 2004-02-16
TW200407543A (en) 2004-05-16
US7333896B2 (en) 2008-02-19
US20080103063A1 (en) 2008-05-01
US7395160B2 (en) 2008-07-01
AU2003261273A8 (en) 2004-02-16
TW200403434A (en) 2004-03-01
US7333895B2 (en) 2008-02-19
WO2004011905A2 (en) 2004-02-05
AU2003304161A8 (en) 2005-01-21
AU2003268031A1 (en) 2004-02-16
WO2004106887A3 (en) 2005-05-12
US20040058372A1 (en) 2004-03-25
TW200407540A (en) 2004-05-16
WO2004106887A2 (en) 2004-12-09
WO2004011904A3 (en) 2004-07-08
AR040712A1 (en) 2005-04-20
US20040053333A1 (en) 2004-03-18
AU2003304161A1 (en) 2005-01-21
US20080195323A1 (en) 2008-08-14
AR040711A1 (en) 2005-04-13
WO2004011904A2 (en) 2004-02-05
US20040058388A1 (en) 2004-03-25
AU2003268031A8 (en) 2004-02-16

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