WO2004021959B1 - Positioning system for a nerve stimulator needle - Google Patents

Positioning system for a nerve stimulator needle

Info

Publication number
WO2004021959B1
WO2004021959B1 PCT/US2003/027244 US0327244W WO2004021959B1 WO 2004021959 B1 WO2004021959 B1 WO 2004021959B1 US 0327244 W US0327244 W US 0327244W WO 2004021959 B1 WO2004021959 B1 WO 2004021959B1
Authority
WO
WIPO (PCT)
Prior art keywords
tip
shield
dermal layers
corium
nerve
Prior art date
Application number
PCT/US2003/027244
Other languages
French (fr)
Other versions
WO2004021959A3 (en
WO2004021959A2 (en
Inventor
William F Urmey
Original Assignee
William F Urmey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by William F Urmey filed Critical William F Urmey
Priority to AU2003276857A priority Critical patent/AU2003276857A1/en
Priority to JP2004534385A priority patent/JP4546829B2/en
Priority to EP03794541A priority patent/EP1534130A4/en
Priority to BR0314328-7A priority patent/BR0314328A/en
Publication of WO2004021959A2 publication Critical patent/WO2004021959A2/en
Publication of WO2004021959A3 publication Critical patent/WO2004021959A3/en
Publication of WO2004021959B1 publication Critical patent/WO2004021959B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4887—Locating particular structures in or on the body
    • A61B5/4893—Nerves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B90/11—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis with guides for needles or instruments, e.g. arcuate slides or ball joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/12—Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters

Abstract

A target nerve or nerve plexus registration point is located utilizing a nerve stimulator needle (18) positioned in a bore (14) of a carrier (12). The carrier (12) is configured with an electrically nonconductive smooth curved surface (16) at a distal end of the bore. The needle tip (28) is fixed in an operative cutaneous electrode position and the smooth curved surface (16) of the carrier (12) is forced against and compresses the epidermis, corium and subcutaneous tissue and traverses cutaneous surfaces to locate a target nerve or nerve plexus without physical penetration by the needle tip (28). The needle (18) is then inserted at the located point.

Claims

26
AMENDED CLAIMS
[received by the International Bureau on 28 May 2004 (28.05.04); new claims 21, 22 and 23 added; remaining claims unchanged (3 pages)]
c) initiating current flow through the patient from the tip by noninvasively contacting dermal layers of the patient with the tip, d) varying the point of contact between the tip and the dermal layers, e) ascertaining a point of contact in registration with a target nerve or nerve plexus by eliciting a neurological response to current flow during step d) and f) advancing the needle into the patient at the ascertained point of contact.
19. A method of administering an anesthetic blockade or other medical procedure to a patient in accordance with claim 1 S wherein step d) is practiced in the absence of a coupling gel.
20. Λ method of administering an anesthetic blockade in accordance with claim 12 wherein step £) is practiced in the absence of a coupling gel
21. A positioning system for cutaneously locating a target nerve or nerve plexus of a subject having cutaneous dermal layers including a corium, the system comprising a carrier, the carrier having a smooth blunt shield, the shield being electrically nonconductive, an electrode including a tip, the tip having an operative position relative to the shield, the tip being selectively coupled to a current supply for eliciting a neurological response to current flow, the operative position being such that when the shield is pressed against the dermal layers, the tip contacts the dermal layers without invasive penetration of the corium.
22. A positioning system for locating a target nerve or nerve plexus of a subject having cutaneous dermal layers including a corium, the system comprising a carrier, the carrier having a shield with a smooth contour, the shield being electrically nonconductive, an electrode, the electrode having a tip, the tip being selectively coupled to a current supply, the tip having an operative position relative to the shield such that when the shield is pressed against the dermal layers , the tip contacts the dermal layers without invasive penetration of the corium and when current is supplied to the tip, current flows througli the subject for eliciting a neurologic response which varies as a function of the lateral position of the tip on the dermal layers relative to the target nerve or nerve plexus.
23. A method of cutaneously locating a target nerve or nerve plexus of a patient having dermal layers including a corium for the administration of an anesthetic blockade or other medical procedure, the method comprising the steps of: a) providing a carrier having an electrically nonconductive smooth blunt shield, b) providing an electrode having a lip, c) positioning the tip relative to the shield such that when the shield is pressed against the dermal layers, the tip contacts the dermal layers without penetration of the corium, 28
d) coupling a current supply to the tip, e) pressing the shield against the dermal layers so that the tip contacts the dermal layers without penetrating the corium, f) laterally moving the shield relative to the dermal layers while continuing to press the shield against the dermal layers without penetrating the corium, and g) ascertaining a position of the tip in registration with the target nerve or nerve plexus by eliciting a neurological response to current flow during step f).
PCT/US2003/027244 2002-09-04 2003-09-03 Positioning system for a nerve stimulator needle WO2004021959A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2003276857A AU2003276857A1 (en) 2002-09-04 2003-09-03 Positioning system for a nerve stimulator needle
JP2004534385A JP4546829B2 (en) 2002-09-04 2003-09-03 Positioning device for nerve stimulation needles
EP03794541A EP1534130A4 (en) 2002-09-04 2003-09-03 Positioning system for a nerve stimulator needle
BR0314328-7A BR0314328A (en) 2002-09-04 2003-09-03 Positioning system for a nerve stimulating needle

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40802602P 2002-09-04 2002-09-04
US60/408,026 2002-09-04

Publications (3)

Publication Number Publication Date
WO2004021959A2 WO2004021959A2 (en) 2004-03-18
WO2004021959A3 WO2004021959A3 (en) 2004-07-01
WO2004021959B1 true WO2004021959B1 (en) 2004-08-19

Family

ID=31978548

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/027244 WO2004021959A2 (en) 2002-09-04 2003-09-03 Positioning system for a nerve stimulator needle

Country Status (6)

Country Link
US (2) US7282033B2 (en)
EP (1) EP1534130A4 (en)
JP (1) JP4546829B2 (en)
AU (1) AU2003276857A1 (en)
BR (1) BR0314328A (en)
WO (1) WO2004021959A2 (en)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8611993B2 (en) * 2000-03-13 2013-12-17 Arrow International, Inc. Pre-loaded lockable stimulating catheter for delivery of anaesthetic drugs
EP1417000B1 (en) 2001-07-11 2018-07-11 Nuvasive, Inc. System for determining nerve proximity during surgery
EP1435828A4 (en) 2001-09-25 2009-11-11 Nuvasive Inc System and methods for performing surgical procedures and assessments
US8147421B2 (en) 2003-01-15 2012-04-03 Nuvasive, Inc. System and methods for determining nerve direction to a surgical instrument
WO2006010837A2 (en) * 2004-06-24 2006-02-02 Sphergen Device for transferring molecules to cells using an electric force
US20100331883A1 (en) 2004-10-15 2010-12-30 Schmitz Gregory P Access and tissue modification systems and methods
US8062300B2 (en) 2006-05-04 2011-11-22 Baxano, Inc. Tissue removal with at least partially flexible devices
US9247952B2 (en) 2004-10-15 2016-02-02 Amendia, Inc. Devices and methods for tissue access
US7738969B2 (en) * 2004-10-15 2010-06-15 Baxano, Inc. Devices and methods for selective surgical removal of tissue
US8613745B2 (en) 2004-10-15 2013-12-24 Baxano Surgical, Inc. Methods, systems and devices for carpal tunnel release
US20110190772A1 (en) 2004-10-15 2011-08-04 Vahid Saadat Powered tissue modification devices and methods
US8192435B2 (en) 2004-10-15 2012-06-05 Baxano, Inc. Devices and methods for tissue modification
US7578819B2 (en) * 2005-05-16 2009-08-25 Baxano, Inc. Spinal access and neural localization
US8257356B2 (en) 2004-10-15 2012-09-04 Baxano, Inc. Guidewire exchange systems to treat spinal stenosis
US7887538B2 (en) 2005-10-15 2011-02-15 Baxano, Inc. Methods and apparatus for tissue modification
US8221397B2 (en) 2004-10-15 2012-07-17 Baxano, Inc. Devices and methods for tissue modification
US8430881B2 (en) 2004-10-15 2013-04-30 Baxano, Inc. Mechanical tissue modification devices and methods
US7938830B2 (en) 2004-10-15 2011-05-10 Baxano, Inc. Powered tissue modification devices and methods
US8048080B2 (en) 2004-10-15 2011-11-01 Baxano, Inc. Flexible tissue rasp
US7963915B2 (en) * 2004-10-15 2011-06-21 Baxano, Inc. Devices and methods for tissue access
US20060122458A1 (en) * 2004-10-15 2006-06-08 Baxano, Inc. Devices and methods for tissue access
US9101386B2 (en) 2004-10-15 2015-08-11 Amendia, Inc. Devices and methods for treating tissue
US8568331B2 (en) * 2005-02-02 2013-10-29 Nuvasive, Inc. System and methods for monitoring during anterior surgery
US20110060238A1 (en) * 2005-03-01 2011-03-10 Checkpoint Surgical, Llc Systems and methods for intra-operative physiological functional stimulation
US20110060243A1 (en) * 2005-03-01 2011-03-10 Checkpoint Surgical, Llc Systems and methods for intra-operative regional neural stimulation
US7878981B2 (en) * 2005-03-01 2011-02-01 Checkpoint Surgical, Llc Systems and methods for intra-operative stimulation
US20110054346A1 (en) * 2005-03-01 2011-03-03 Checkpoint Surgical, Llc Systems and methods for Intra-operative semi-quantitative threshold neural response testing related applications
US7896815B2 (en) * 2005-03-01 2011-03-01 Checkpoint Surgical, Llc Systems and methods for intra-operative stimulation
US20060200219A1 (en) * 2005-03-01 2006-09-07 Ndi Medical, Llc Systems and methods for differentiating and/or identifying tissue regions innervated by targeted nerves for diagnostic and/or therapeutic purposes
US10154792B2 (en) 2005-03-01 2018-12-18 Checkpoint Surgical, Inc. Stimulation device adapter
US20110060242A1 (en) * 2005-03-01 2011-03-10 Checkpoint Surgical, Llc Systems and methods for intra-operative stimulation within a surgical field
US8740783B2 (en) * 2005-07-20 2014-06-03 Nuvasive, Inc. System and methods for performing neurophysiologic assessments with pressure monitoring
US8206312B2 (en) * 2005-09-22 2012-06-26 Nuvasive, Inc. Multi-channel stimulation threshold detection algorithm for use in neurophysiology monitoring
US8568317B1 (en) 2005-09-27 2013-10-29 Nuvasive, Inc. System and methods for nerve monitoring
US20080086034A1 (en) 2006-08-29 2008-04-10 Baxano, Inc. Tissue Access Guidewire System and Method
US20080033465A1 (en) * 2006-08-01 2008-02-07 Baxano, Inc. Multi-Wire Tissue Cutter
US8092456B2 (en) 2005-10-15 2012-01-10 Baxano, Inc. Multiple pathways for spinal nerve root decompression from a single access point
US8062298B2 (en) 2005-10-15 2011-11-22 Baxano, Inc. Flexible tissue removal devices and methods
US8366712B2 (en) 2005-10-15 2013-02-05 Baxano, Inc. Multiple pathways for spinal nerve root decompression from a single access point
CA2664172C (en) * 2006-09-16 2016-03-29 Terence Gilhuly Improved sensors and sensing for monitoring neuromuscular blockade
EP2088941A4 (en) * 2006-12-07 2010-09-01 Baxano Inc Tissue removal devices and methods
US7699809B2 (en) * 2006-12-14 2010-04-20 Urmey William F Catheter positioning system
EP2091604B1 (en) * 2006-12-14 2012-09-05 William F. Urmey Catheter positioning system
US7987001B2 (en) * 2007-01-25 2011-07-26 Warsaw Orthopedic, Inc. Surgical navigational and neuromonitoring instrument
US8374673B2 (en) * 2007-01-25 2013-02-12 Warsaw Orthopedic, Inc. Integrated surgical navigational and neuromonitoring system having automated surgical assistance and control
US20080183068A1 (en) * 2007-01-25 2008-07-31 Warsaw Orthopedic, Inc. Integrated Visualization of Surgical Navigational and Neural Monitoring Information
US20080183188A1 (en) * 2007-01-25 2008-07-31 Warsaw Orthopedic, Inc. Integrated Surgical Navigational and Neuromonitoring System
US20080183074A1 (en) * 2007-01-25 2008-07-31 Warsaw Orthopedic, Inc. Method and apparatus for coordinated display of anatomical and neuromonitoring information
US9042978B2 (en) * 2007-05-11 2015-05-26 Neurometrix, Inc. Method and apparatus for quantitative nerve localization
FR2917294A1 (en) * 2007-06-14 2008-12-19 Philippe Campana Medical intervention system for e.g. locoregional anesthesia operation, has probe comprising interface for controlling remote control unit that remotely controls controllable additional equipments such as nerve stimulator and syringe-driver
WO2008157513A1 (en) * 2007-06-15 2008-12-24 Baxano, Inc. Devices and methods for measuring the space around a nerve root
US20090062750A1 (en) * 2007-08-27 2009-03-05 Morteza Gharib Medical device for injecting a local anesthetic
WO2009032363A1 (en) 2007-09-06 2009-03-12 Baxano, Inc. Method, system and apparatus for neural localization
US8192436B2 (en) 2007-12-07 2012-06-05 Baxano, Inc. Tissue modification devices
US8398641B2 (en) 2008-07-01 2013-03-19 Baxano, Inc. Tissue modification devices and methods
US9314253B2 (en) 2008-07-01 2016-04-19 Amendia, Inc. Tissue modification devices and methods
US8409206B2 (en) 2008-07-01 2013-04-02 Baxano, Inc. Tissue modification devices and methods
CA2730732A1 (en) 2008-07-14 2010-01-21 Baxano, Inc. Tissue modification devices
US20110208112A1 (en) * 2008-08-11 2011-08-25 Morteza Gharib Medical device for injecting local anesthetic
US8137285B1 (en) 2008-08-26 2012-03-20 Rhythmlink International, Llc Monopolar stimulation probe system
EP2405823A4 (en) 2009-03-13 2012-07-04 Baxano Inc Flexible neural localization devices and methods
US8394102B2 (en) 2009-06-25 2013-03-12 Baxano, Inc. Surgical tools for treatment of spinal stenosis
US8965482B2 (en) 2010-09-30 2015-02-24 Nevro Corporation Systems and methods for positioning implanted devices in a patient
US8805519B2 (en) 2010-09-30 2014-08-12 Nevro Corporation Systems and methods for detecting intrathecal penetration
US8986283B2 (en) 2011-05-18 2015-03-24 Solo-Dex, Llc Continuous anesthesia nerve conduction apparatus, system and method thereof
CA3192660A1 (en) 2011-05-18 2012-11-22 Solo-Dex, Inc. Continuous anesthesia nerve conduction apparatus, system and method
AU2012318586B2 (en) 2011-10-04 2017-06-08 Nevro Corporation Modeling positions of implanted devices in a patient
US9320872B2 (en) * 2011-10-14 2016-04-26 William F. Urmey Catheter positioning system
US9949651B2 (en) 2011-11-01 2018-04-24 DePuy Synthes Products, Inc. Intraoperative neurophysiological monitoring system
US20130184551A1 (en) * 2012-01-13 2013-07-18 Jude V. Paganelli Neuromonitoring dilator
US8676331B2 (en) 2012-04-02 2014-03-18 Nevro Corporation Devices for controlling spinal cord modulation for inhibiting pain, and associated systems and methods, including controllers for automated parameter selection
EP2777510A1 (en) * 2013-03-14 2014-09-17 Tracto LLC Surgical retractor support system
EP2968737A4 (en) 2013-03-15 2016-11-09 Concert Medical Llc Method and system for controlling delivery of a fluid to and from a patient
US10098585B2 (en) 2013-03-15 2018-10-16 Cadwell Laboratories, Inc. Neuromonitoring systems and methods
US9427224B1 (en) * 2013-05-14 2016-08-30 Dhiraj JEYANANDARAJAN Apparatus and methods for surgical access
CA2913074C (en) 2013-05-30 2023-09-12 Graham H. Creasey Topical neurological stimulation
US11229789B2 (en) 2013-05-30 2022-01-25 Neurostim Oab, Inc. Neuro activator with controller
WO2015038167A1 (en) 2013-09-16 2015-03-19 Empire Technology Development, Llc Nerve location detection
EP2870979B1 (en) 2013-11-08 2021-01-06 Nuvectra Corporation Implantable medical lead for stimulation of multiple nerves
KR20170045286A (en) 2014-08-26 2017-04-26 아벤트, 인크. Method and system for identification of source of chronic pain and treatment
US11077301B2 (en) 2015-02-21 2021-08-03 NeurostimOAB, Inc. Topical nerve stimulator and sensor for bladder control
US9935395B1 (en) 2017-01-23 2018-04-03 Cadwell Laboratories, Inc. Mass connection plate for electrical connectors
WO2018165391A1 (en) 2017-03-09 2018-09-13 Nevro Corp. Paddle leads and delivery tools, and associated systems and methods
WO2019094365A1 (en) 2017-11-07 2019-05-16 Neurostim Oab, Inc. Non-invasive nerve activator with adaptive circuit
EP3758793A4 (en) 2018-03-29 2021-12-08 Nevro Corp. Leads having sidewall openings, and associated systems and methods
US11253182B2 (en) 2018-05-04 2022-02-22 Cadwell Laboratories, Inc. Apparatus and method for polyphasic multi-output constant-current and constant-voltage neurophysiological stimulation
US11443649B2 (en) 2018-06-29 2022-09-13 Cadwell Laboratories, Inc. Neurophysiological monitoring training simulator
CA3144957A1 (en) 2019-06-26 2020-12-30 Neurostim Technologies Llc Non-invasive nerve activator with adaptive circuit
CA3152451A1 (en) 2019-12-16 2021-06-24 Michael Bernard Druke Non-invasive nerve activator with boosted charge delivery
US11246637B2 (en) 2020-05-11 2022-02-15 Alphatec Spine, Inc. Stimulating targeting needle

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52104289U (en) * 1976-02-05 1977-08-08
JPS52104289A (en) 1976-02-27 1977-09-01 Hitachi Ltd Atomic spectrum generator
JPS577538U (en) * 1980-06-12 1982-01-14
CS228175B1 (en) 1982-02-26 1984-05-14 Kocur Pavel Ing.,Cs Contact electrode
US4788985A (en) * 1982-09-30 1988-12-06 Medtest Corporation Device for cell sampling in a body cavity
CN1012257B (en) * 1986-09-09 1991-04-03 顾涵森 Bioelectric signal measuring apparatus
DE8803153U1 (en) * 1988-03-09 1988-06-23 B. Braun Melsungen Ag, 3508 Melsungen, De
US5129402A (en) * 1991-02-19 1992-07-14 Accu-Med Corporation Apparatus for collecting and/or growing protected biological specimens
US5284153A (en) * 1992-04-14 1994-02-08 Brigham And Women's Hospital Method for locating a nerve and for protecting nerves from injury during surgery
US5456662A (en) * 1993-02-02 1995-10-10 Edwards; Stuart D. Method for reducing snoring by RF ablation of the uvula
US5327902A (en) * 1993-05-14 1994-07-12 Lemmen Roger D Apparatus for use in nerve conduction studies
AU5448496A (en) * 1995-04-10 1996-10-30 St. Luke's-Roosevelt Hospital Peripheral nerve stimulation device for unassisted nerve blo ckade
DE19530869A1 (en) 1995-08-22 1997-02-27 Sterimed Gmbh Puncturing and / or catheterizing device for probing nerves
US5779642A (en) * 1996-01-16 1998-07-14 Nightengale; Christopher Interrogation device and method
US5853373A (en) * 1996-08-05 1998-12-29 Becton, Dickinson And Company Bi-level charge pulse apparatus to facilitate nerve location during peripheral nerve block procedures
JPH1071183A (en) * 1996-08-30 1998-03-17 Yoshizo Abe Acupuncture point resistance measuring instrument
US5928158A (en) * 1997-03-25 1999-07-27 Aristides; Arellano Medical instrument with nerve sensor
US6564078B1 (en) * 1998-12-23 2003-05-13 Nuvasive, Inc. Nerve surveillance cannula systems
US6312392B1 (en) * 2000-04-06 2001-11-06 Garrett D. Herzon Bipolar handheld nerve locator and evaluator
US6533732B1 (en) * 2000-10-17 2003-03-18 William F. Urmey Nerve stimulator needle guidance system
KR20080098054A (en) 2006-02-09 2008-11-06 헤드워터스 테크놀로지 이노베이션 엘엘씨 Polymeric materials incorporating carbon nanostructures and methods for making same

Also Published As

Publication number Publication date
JP2005537858A (en) 2005-12-15
US7918802B2 (en) 2011-04-05
EP1534130A2 (en) 2005-06-01
AU2003276857A8 (en) 2004-03-29
US20080015612A1 (en) 2008-01-17
WO2004021959A3 (en) 2004-07-01
WO2004021959A2 (en) 2004-03-18
BR0314328A (en) 2005-07-05
US20040059247A1 (en) 2004-03-25
JP4546829B2 (en) 2010-09-22
EP1534130A4 (en) 2008-09-03
US7282033B2 (en) 2007-10-16
AU2003276857A1 (en) 2004-03-29

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