WO2004024227A3 - Systems of sperm cell preservation and processing - Google Patents

Systems of sperm cell preservation and processing Download PDF

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Publication number
WO2004024227A3
WO2004024227A3 PCT/US2003/030814 US0330814W WO2004024227A3 WO 2004024227 A3 WO2004024227 A3 WO 2004024227A3 US 0330814 W US0330814 W US 0330814W WO 2004024227 A3 WO2004024227 A3 WO 2004024227A3
Authority
WO
WIPO (PCT)
Prior art keywords
sperm
processing
sperm cell
preservation
sperm cells
Prior art date
Application number
PCT/US2003/030814
Other languages
French (fr)
Other versions
WO2004024227A2 (en
Inventor
William Maxwell Chisho Maxwell
Fiona Kate Hollinshead
Justine Kellie O'brien
Gareth Evans
Original Assignee
Xy Inc
William Maxwell Chisho Maxwell
Fiona Kate Hollinshead
Justine Kellie O'brien
Gareth Evans
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xy Inc, William Maxwell Chisho Maxwell, Fiona Kate Hollinshead, Justine Kellie O'brien, Gareth Evans filed Critical Xy Inc
Priority to CA2538118A priority Critical patent/CA2538118C/en
Priority to AU2003277099A priority patent/AU2003277099B2/en
Priority to EP10186250.6A priority patent/EP2316933B1/en
Priority to BRPI0314218A priority patent/BRPI0314218B8/en
Priority to DK03795716.4T priority patent/DK1546325T3/en
Priority to EP03795716A priority patent/EP1546325B1/en
Priority to AT03795716T priority patent/ATE519843T1/en
Priority to NZ539388A priority patent/NZ539388A/en
Publication of WO2004024227A2 publication Critical patent/WO2004024227A2/en
Publication of WO2004024227A3 publication Critical patent/WO2004024227A3/en
Priority to HK06103533.2A priority patent/HK1083471A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/061—Sperm cells, spermatogonia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0604—Whole embryos; Culture medium therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/42—Gynaecological or obstetrical instruments or methods
    • A61B17/425—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation
    • A61B17/43—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation for artificial insemination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8771—Bovine embryos
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8773—Ovine embryos
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/101—Bovine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/103—Ovine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/10—Conditioning of cells for in vitro fecondation or nuclear transfer

Abstract

The preservation of sperm cells, and other processing of sperm cells, are disclosed. The present invention is directed in some embodiments to sperm cell preservation, as sperm cell preservation may further relate to artificial insemination, in vitro fertilization, super-ovulation, mammal production, sperm samples, and sperm cell processing, generally. The present invention is also directed in some embodiments to sperm cell processing features, such as collecting, handling, sorting, storage, transportation, use, fertilization, or insemination techniques. Sperm cell preservation in accordance with the present invention may address maintenance or enhancement of sperm quality, and in some embodiments one or more sperm cell characteristics, such as viability, motility, and functionality. Fertilization rates may also be maintained or enhanced. An embodiment may comprise obtaining sperm cells (10). The sperm cells may be cryoperserved (20) and thawed (30). Processing (40) may be performed on the sperm cells and cryopreservation of the sperm cells (50).
PCT/US2003/030814 2002-09-13 2003-09-15 Systems of sperm cell preservation and processing WO2004024227A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
CA2538118A CA2538118C (en) 2002-09-13 2003-09-15 Sperm cell preservation and processing systems
AU2003277099A AU2003277099B2 (en) 2002-09-13 2003-09-15 Systems of sperm cell preservation and processing
EP10186250.6A EP2316933B1 (en) 2002-09-13 2003-09-15 Systems of sperm cell preservation and processing
BRPI0314218A BRPI0314218B8 (en) 2002-09-13 2003-09-15 sperm cell preservation and processing systems
DK03795716.4T DK1546325T3 (en) 2002-09-13 2003-09-15 Sperm Treatment and Preservation Systems
EP03795716A EP1546325B1 (en) 2002-09-13 2003-09-15 Systems of sperm cell preservation and processing
AT03795716T ATE519843T1 (en) 2002-09-13 2003-09-15 SYSTEMS FOR MAINTAINING AND PROCESSING SPERM CELLS
NZ539388A NZ539388A (en) 2002-09-13 2003-09-15 Sperm cell and semen cryopreservation and processing systems
HK06103533.2A HK1083471A1 (en) 2002-09-13 2006-03-21 Sperm cell preservation and processing systems

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US41088402P 2002-09-13 2002-09-13
US60/410,884 2002-09-13
US10/340,881 US7169548B2 (en) 2002-09-13 2003-01-09 Sperm cell processing and preservation systems
US10/340,881 2003-01-09

Publications (2)

Publication Number Publication Date
WO2004024227A2 WO2004024227A2 (en) 2004-03-25
WO2004024227A3 true WO2004024227A3 (en) 2004-11-04

Family

ID=31996979

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/030814 WO2004024227A2 (en) 2002-09-13 2003-09-15 Systems of sperm cell preservation and processing

Country Status (12)

Country Link
US (3) US7169548B2 (en)
EP (2) EP1546325B1 (en)
CN (1) CN100581355C (en)
AT (1) ATE519843T1 (en)
AU (1) AU2003277099B2 (en)
BR (1) BRPI0314218B8 (en)
CA (1) CA2538118C (en)
DK (2) DK1546325T3 (en)
ES (1) ES2813855T3 (en)
HK (1) HK1083471A1 (en)
NZ (2) NZ539388A (en)
WO (1) WO2004024227A2 (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US7758811B2 (en) 2003-03-28 2010-07-20 Inguran, Llc System for analyzing particles using multiple flow cytometry units
US7820425B2 (en) 1999-11-24 2010-10-26 Xy, Llc Method of cryopreserving selected sperm cells
US7833147B2 (en) 2004-07-22 2010-11-16 Inguran, LLC. Process for enriching a population of sperm cells
US7838210B2 (en) 2004-03-29 2010-11-23 Inguran, LLC. Sperm suspensions for sorting into X or Y chromosome-bearing enriched populations
US7929137B2 (en) 1997-01-31 2011-04-19 Xy, Llc Optical apparatus
US8137967B2 (en) 2000-11-29 2012-03-20 Xy, Llc In-vitro fertilization systems with spermatozoa separated into X-chromosome and Y-chromosome bearing populations
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
US8497063B2 (en) 2002-08-01 2013-07-30 Xy, Llc Sex selected equine embryo production system
US9145590B2 (en) 2000-05-09 2015-09-29 Xy, Llc Methods and apparatus for high purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa
US9365822B2 (en) 1997-12-31 2016-06-14 Xy, Llc System and method for sorting cells

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NZ509434A (en) 1998-07-30 2004-03-26 Univ Colorado State Res Found Equine system for non-surgical artificial insemination
BR0111618A (en) * 2000-06-12 2004-06-29 Xy Inc Integrated herd control system using isolated populations of x-chromosome-containing and y-chromosome-containing sperm
US7855078B2 (en) 2002-08-15 2010-12-21 Xy, Llc High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
WO2004104178A2 (en) 2003-05-15 2004-12-02 Xy, Inc. Efficient haploid cell sorting for flow cytometer systems
US9919014B2 (en) * 2005-04-05 2018-03-20 Membrane Protective Technologies, Inc. Reproductive cell maintenance system
US11857588B2 (en) * 2005-04-05 2024-01-02 Membrane Protective Technologies, Inc. Reproductive cell maintenance system
US20080269549A1 (en) * 2007-04-27 2008-10-30 The Jackson Laboratory Method, article, and apparatus for cryopreservation of biological samples
US8512224B2 (en) * 2009-01-24 2013-08-20 Xy, Llc Method of producing an inseminate
US8251887B2 (en) * 2009-01-24 2012-08-28 Xihe Li Reproductive technology of low dose semen production and in vitro/in vitro fertilization in domestic animals
NZ629047A (en) 2010-06-09 2016-01-29 Xy Llc A heterogeneous inseminate system
RU2626932C2 (en) * 2011-12-09 2017-08-02 Дзе Кьюрейторз Оф Дзе Юниверсити Оф Миссури Inorganic pyrophosphate and its application
US9433195B2 (en) 2012-06-06 2016-09-06 Inguran, Llc Methods for increasing genetic progress in a line or breed of swine using sex-selected sperm cells
US9888990B2 (en) 2012-06-06 2018-02-13 Inguran, Llc Methods for use of sex sorted semen to improve genetic management in swine
US10379026B2 (en) 2012-08-29 2019-08-13 Inguran, Llc Cell processing using magnetic particles
AU2013309137B2 (en) 2012-08-29 2016-11-10 Inguran, Llc Magnetic removal or identification of damaged or compromised cells or cellular structures
JP7142842B2 (en) * 2017-06-30 2022-09-28 国立大学法人広島大学 Mammalian sperm separation method, artificial insemination method and in vitro fertilization method

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