WO2004032829A3 - Immunostimulatory compositions and methods of stimulating an immune response - Google Patents

Immunostimulatory compositions and methods of stimulating an immune response Download PDF

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Publication number
WO2004032829A3
WO2004032829A3 PCT/US2003/025523 US0325523W WO2004032829A3 WO 2004032829 A3 WO2004032829 A3 WO 2004032829A3 US 0325523 W US0325523 W US 0325523W WO 2004032829 A3 WO2004032829 A3 WO 2004032829A3
Authority
WO
WIPO (PCT)
Prior art keywords
immune response
stimulating
methods
immunostimulatory compositions
compositions
Prior art date
Application number
PCT/US2003/025523
Other languages
French (fr)
Other versions
WO2004032829A2 (en
Inventor
Ross M Kedl
George W Griesgraber
Isidro Angelo E Zarraga
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Priority to AU2003299863A priority Critical patent/AU2003299863B2/en
Priority to BRPI0313587-0A priority patent/BR0313587A/en
Priority to AT03808061T priority patent/ATE488246T1/en
Priority to MXPA05001647A priority patent/MXPA05001647A/en
Priority to CN038184702A priority patent/CN1671412B/en
Priority to DK03808061.0T priority patent/DK1545597T3/en
Priority to DE60335010T priority patent/DE60335010D1/en
Priority to JP2004543241A priority patent/JP4860923B2/en
Priority to EP03808061A priority patent/EP1545597B1/en
Priority to KR1020057002485A priority patent/KR101088615B1/en
Priority to CA2495570A priority patent/CA2495570C/en
Priority to NZ538812A priority patent/NZ538812A/en
Publication of WO2004032829A2 publication Critical patent/WO2004032829A2/en
Publication of WO2004032829A3 publication Critical patent/WO2004032829A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention provides immunostimulatory compositions that include an immune response modifier portion paired with an antigenic portion.
PCT/US2003/025523 2002-08-15 2003-08-14 Immunostimulatory compositions and methods of stimulating an immune response WO2004032829A2 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
AU2003299863A AU2003299863B2 (en) 2002-08-15 2003-08-14 Immunostimulatory compositions and methods of stimulating an immune response
BRPI0313587-0A BR0313587A (en) 2002-08-15 2003-08-14 immunostimulatory compositions and methods of stimulating an immune response
AT03808061T ATE488246T1 (en) 2002-08-15 2003-08-14 IMMUNO-STIMULATORY COMPOSITIONS AND METHODS FOR STIMULATING AN IMMUNE RESPONSE
MXPA05001647A MXPA05001647A (en) 2002-08-15 2003-08-14 Immunostimulatory compositions and methods of stimulating an immune response.
CN038184702A CN1671412B (en) 2002-08-15 2003-08-14 Immunostimulatory compositions and methods of stimulating an immune response
DK03808061.0T DK1545597T3 (en) 2002-08-15 2003-08-14 Immune Stimulating Compositions and Methods for Stimulating an Immune Response
DE60335010T DE60335010D1 (en) 2002-08-15 2003-08-14 IMMUNOSTIMULATORY COMPOSITIONS AND METHOD FOR STIMULATING AN IMMUNE RESPONSE
JP2004543241A JP4860923B2 (en) 2002-08-15 2003-08-14 Immunostimulatory composition and method of stimulating immune response
EP03808061A EP1545597B1 (en) 2002-08-15 2003-08-14 Immunostimulatory compositions and methods of stimulating an immune response
KR1020057002485A KR101088615B1 (en) 2002-08-15 2003-08-14 Immunostimulatory compositions and methods of stimulating an immune response
CA2495570A CA2495570C (en) 2002-08-15 2003-08-14 Immunostimulatory compositions and methods of stimulating an immune response
NZ538812A NZ538812A (en) 2002-08-15 2003-08-14 Immunostimulatory compositions and methods of stimulating an immune response

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40384602P 2002-08-15 2002-08-15
US60/403,846 2002-08-15

Publications (2)

Publication Number Publication Date
WO2004032829A2 WO2004032829A2 (en) 2004-04-22
WO2004032829A3 true WO2004032829A3 (en) 2004-12-09

Family

ID=32093749

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/025523 WO2004032829A2 (en) 2002-08-15 2003-08-14 Immunostimulatory compositions and methods of stimulating an immune response

Country Status (16)

Country Link
US (1) US7427629B2 (en)
EP (2) EP1545597B1 (en)
JP (2) JP4860923B2 (en)
KR (1) KR101088615B1 (en)
CN (1) CN1671412B (en)
AT (1) ATE488246T1 (en)
AU (1) AU2003299863B2 (en)
BR (1) BR0313587A (en)
CA (1) CA2495570C (en)
DE (1) DE60335010D1 (en)
DK (1) DK1545597T3 (en)
ES (1) ES2355819T3 (en)
MX (1) MXPA05001647A (en)
NZ (1) NZ538812A (en)
PT (1) PT1545597E (en)
WO (1) WO2004032829A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9107919B2 (en) 2009-02-06 2015-08-18 Telormedix Sa Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration
US9242980B2 (en) 2010-08-17 2016-01-26 3M Innovative Properties Company Lipidated immune response modifier compound compositions, formulations, and methods

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UA67760C2 (en) * 1997-12-11 2004-07-15 Міннесота Майнінг Енд Мануфакчурінг Компані Imidazonaphthyridines and use thereof to induce the biosynthesis of cytokines
US6756382B2 (en) * 1999-06-10 2004-06-29 3M Innovative Properties Company Amide substituted imidazoquinolines
US6331539B1 (en) * 1999-06-10 2001-12-18 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines
US6660735B2 (en) * 2000-12-08 2003-12-09 3M Innovative Properties Company Urea substituted imidazoquinoline ethers
US6667312B2 (en) * 2000-12-08 2003-12-23 3M Innovative Properties Company Thioether substituted imidazoquinolines
US6664265B2 (en) 2000-12-08 2003-12-16 3M Innovative Properties Company Amido ether substituted imidazoquinolines
WO2006091720A2 (en) * 2000-12-08 2006-08-31 3M Innovative Properties Company Compositions and methods for targeted delivery of immune response modifiers
US6545016B1 (en) 2000-12-08 2003-04-08 3M Innovative Properties Company Amide substituted imidazopyridines
UA74852C2 (en) 2000-12-08 2006-02-15 3M Innovative Properties Co Urea-substituted imidazoquinoline ethers
US6664264B2 (en) * 2000-12-08 2003-12-16 3M Innovative Properties Company Thioether substituted imidazoquinolines
US6677349B1 (en) * 2001-12-21 2004-01-13 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines
ES2541132T3 (en) * 2002-02-22 2015-07-16 Meda Ab Method to reduce and treat UV-B-induced immunosuppression
EP3006043B1 (en) * 2002-04-04 2019-05-29 Zoetis Belgium S.A. Immunostimulatory g,u-containing oligoribonucleotides
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US20040265351A1 (en) * 2003-04-10 2004-12-30 Miller Richard L. Methods and compositions for enhancing immune response
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