WO2004033038A3 - Method and apparatus for the delivery of brachytherapy - Google Patents

Method and apparatus for the delivery of brachytherapy Download PDF

Info

Publication number
WO2004033038A3
WO2004033038A3 PCT/US2003/031298 US0331298W WO2004033038A3 WO 2004033038 A3 WO2004033038 A3 WO 2004033038A3 US 0331298 W US0331298 W US 0331298W WO 2004033038 A3 WO2004033038 A3 WO 2004033038A3
Authority
WO
WIPO (PCT)
Prior art keywords
wire
radiation source
cannula
delivery system
tissue site
Prior art date
Application number
PCT/US2003/031298
Other languages
French (fr)
Other versions
WO2004033038A2 (en
Inventor
Barry N Gellman
Jozef Slanda
Kimberly Paddock
Douglas Godshall
Original Assignee
Scimed Life Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scimed Life Systems Inc filed Critical Scimed Life Systems Inc
Priority to EP03755027A priority Critical patent/EP1549397A2/en
Priority to AU2003272825A priority patent/AU2003272825A1/en
Priority to CA002510564A priority patent/CA2510564A1/en
Publication of WO2004033038A2 publication Critical patent/WO2004033038A2/en
Publication of WO2004033038A3 publication Critical patent/WO2004033038A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A61N1/403Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia
    • A61N1/406Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia using implantable thermoseeds or injected particles for localized hyperthermia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1027Interstitial radiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • A61N2005/1009Apparatus for loading seeds into magazines or needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • A61N2005/1011Apparatus for permanent insertion of sources
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N2005/1019Sources therefor
    • A61N2005/1024Seeds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N2005/1019Sources therefor
    • A61N2005/1025Wires

Abstract

A brachytherapy device includes a radiation source and a multi-cannula delivery system for implantation of the radiation source into a body tissue site. The radiation source may be, for example, a substantially straight round wire, a substantially straight flat wire, a detented wire, an embossed wire, a bristled wire, a shaped resilient wire, a twisted round wire, a twisted flat wire, or a coil with or without an inner core, and is adapted for implantation into a body tissue site and for delivery of radiation to the body tissue site. The multi-cannula delivery system includes an outer cannula, an outer stylet, an inner cannula, and an inner stylet. Different configurations of the radiation source according to embodiments of the invention improve distribution of the radiation field in the longitudinal direction and resistance to migration of the radiation source inside a patient’s body. The multi-cannula delivery system provides for faster and more accurate placement of the radiation source.
PCT/US2003/031298 2002-10-04 2003-10-03 Method and apparatus for the delivery of brachytherapy WO2004033038A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP03755027A EP1549397A2 (en) 2002-10-04 2003-10-03 Method and apparatus for the delivery of brachytherapy
AU2003272825A AU2003272825A1 (en) 2002-10-04 2003-10-03 Method and apparatus for the delivery of brachytherapy
CA002510564A CA2510564A1 (en) 2002-10-04 2003-10-03 Method and apparatus for the delivery of brachytherapy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/264,637 US7041047B2 (en) 2002-10-04 2002-10-04 Method and apparatus for the delivery of brachytherapy
US10/264,637 2002-10-04

Publications (2)

Publication Number Publication Date
WO2004033038A2 WO2004033038A2 (en) 2004-04-22
WO2004033038A3 true WO2004033038A3 (en) 2004-09-02

Family

ID=32042280

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/031298 WO2004033038A2 (en) 2002-10-04 2003-10-03 Method and apparatus for the delivery of brachytherapy

Country Status (5)

Country Link
US (1) US7041047B2 (en)
EP (1) EP1549397A2 (en)
AU (1) AU2003272825A1 (en)
CA (1) CA2510564A1 (en)
WO (1) WO2004033038A2 (en)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8668737B2 (en) 1997-10-10 2014-03-11 Senorx, Inc. Tissue marking implant
US8498693B2 (en) 1999-02-02 2013-07-30 Senorx, Inc. Intracorporeal marker and marker delivery device
US20090030309A1 (en) 2007-07-26 2009-01-29 Senorx, Inc. Deployment of polysaccharide markers
US8361082B2 (en) 1999-02-02 2013-01-29 Senorx, Inc. Marker delivery device with releasable plug
US7651505B2 (en) 2002-06-17 2010-01-26 Senorx, Inc. Plugged tip delivery for marker placement
US9820824B2 (en) 1999-02-02 2017-11-21 Senorx, Inc. Deployment of polysaccharide markers for treating a site within a patent
DE60324448D1 (en) 2002-09-10 2008-12-11 Cianna Medical Inc brachytherapy
US7877133B2 (en) 2003-05-23 2011-01-25 Senorx, Inc. Marker or filler forming fluid
US7278970B2 (en) * 2003-07-29 2007-10-09 Goldenberg Alec S Biopsy needles
US20050080314A1 (en) * 2003-10-09 2005-04-14 Terwilliger Richard A. Shielded transport for multiple brachytheapy implants with integrated measuring and cutting board
AU2005214040B2 (en) 2004-02-12 2011-03-31 Neo Vista, Inc. Methods and apparatus for intraocular brachytherapy
US7563222B2 (en) * 2004-02-12 2009-07-21 Neovista, Inc. Methods and apparatus for intraocular brachytherapy
BRPI0515007A (en) 2004-08-12 2008-07-01 Navotek Medical Ltd computerized system for tracking and tracing of irradiated ionization source, sensor for targeting located on an ionized radiation source, method for determining device location, method of locating device manufacturing, and use of ionizing radiation shield
JP4576927B2 (en) * 2004-08-19 2010-11-10 東ソー株式会社 Cleaning composition and cleaning method
US20080262473A1 (en) * 2004-10-19 2008-10-23 Navotek Medical Ltd. Locating a Catheter Tip Using a Tracked Guide
US7662082B2 (en) 2004-11-05 2010-02-16 Theragenics Corporation Expandable brachytherapy device
US10357328B2 (en) 2005-04-20 2019-07-23 Bard Peripheral Vascular, Inc. and Bard Shannon Limited Marking device with retractable cannula
CN101282760A (en) * 2005-08-11 2008-10-08 纳沃特克医药有限公司 Medical treatment system and method using radioactivity based position sensor
EP1922011B1 (en) * 2005-08-11 2012-05-02 Navotek Medical Ltd. Localization of a radioactive source
BRPI0616514A2 (en) * 2005-08-11 2011-06-21 Navotek Medical Ltd medical treatment system and method using position sensor based radioactivity
US7557032B2 (en) * 2005-09-01 2009-07-07 Micron Technology, Inc. Silicided recessed silicon
WO2007053823A2 (en) 2005-10-31 2007-05-10 Biolucent, Inc. Brachytherapy apparatus and methods of using same
US7887476B2 (en) 2005-11-10 2011-02-15 Cianna Medical, Inc. Helical brachytherapy apparatus and methods of using same
US7862496B2 (en) 2005-11-10 2011-01-04 Cianna Medical, Inc. Brachytherapy apparatus and methods for using them
CA2629648A1 (en) 2005-11-15 2007-05-24 Neovista Inc. Methods and apparatus for intraocular brachytherapy
US9072893B2 (en) 2006-06-02 2015-07-07 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
US10369343B2 (en) * 2006-06-30 2019-08-06 Biocompatibles Uk Limited Apparatus and method to convey a fluid
AU2007307854B2 (en) 2006-10-08 2012-01-19 Cianna Medical, Inc. Expandable brachytherapy apparatus
EP3542748B1 (en) 2006-12-12 2023-08-16 C. R. Bard, Inc. Multiple imaging mode tissue marker
ES2432572T3 (en) 2006-12-18 2013-12-04 C.R. Bard, Inc. Biopsy marker with imaging properties generated in situ
US8517907B2 (en) 2007-12-16 2013-08-27 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
EP2296756A1 (en) 2008-06-04 2011-03-23 Neovista, Inc. Handheld radiation delivery system for advancing a radiation source wire
EP2156806A1 (en) * 2008-08-18 2010-02-24 Navotek Medical Ltd. Implantation device for soft tissue markers and other implants
US8636635B2 (en) 2008-08-18 2014-01-28 Cianna Medical, Inc. Brachytherapy apparatus, systems, and methods for using them
US9327061B2 (en) 2008-09-23 2016-05-03 Senorx, Inc. Porous bioabsorbable implant
US8670818B2 (en) 2008-12-30 2014-03-11 C. R. Bard, Inc. Marker delivery device for tissue marker placement
US8663210B2 (en) 2009-05-13 2014-03-04 Novian Health, Inc. Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy
US8814775B2 (en) 2010-03-18 2014-08-26 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
US9883919B2 (en) 2010-07-21 2018-02-06 Cianna Medical, Inc. Brachytherapy apparatus, systems, and methods for using them
US9067063B2 (en) 2010-11-03 2015-06-30 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
US20120190979A1 (en) 2011-01-24 2012-07-26 Actium BioSystems, LLC System for automatically amending energy field characteristics in the application of an energy field to a living organism for treatment of invasive agents
WO2012100355A1 (en) 2011-01-30 2012-08-02 University Health Network Coil electrode for thermal therapy
WO2013032792A1 (en) 2011-08-26 2013-03-07 Actium BioSystems, LLC Apparatus for the generation of an energy field for the treatment of cancer in body cavities and parts that are cavity-like
US9320517B2 (en) 2012-01-12 2016-04-26 Surgical Radiation Products, Llc Targeting implant for external beam radiation
US9943706B2 (en) 2012-01-12 2018-04-17 Surgical Radiation Products, Llc Targeting implant for external beam radiation
BR112015023247B1 (en) * 2013-03-14 2022-04-05 C.R. Bard, Inc. Seed fixation and insertion system in brachytherapy
USD716450S1 (en) 2013-09-24 2014-10-28 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD715942S1 (en) 2013-09-24 2014-10-21 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD715442S1 (en) 2013-09-24 2014-10-14 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD716451S1 (en) 2013-09-24 2014-10-28 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
US9867974B2 (en) * 2015-06-01 2018-01-16 Wisconsin Alumni Research Foundation Microfluidic device for multiplexed point source administration of compounds
US10159850B2 (en) * 2016-01-06 2018-12-25 Covidien Lp Brachytherapy clip and applicator
CN117529350A (en) * 2021-06-30 2024-02-06 阿尔法陶医疗有限公司 Radiation therapy applicator with vertical or angled radial distribution

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5322499A (en) * 1985-09-20 1994-06-21 Liprie Sam F Continuous sheated low dose radioactive core adapted for cutting into short sealed segments
WO1998001179A1 (en) * 1996-07-08 1998-01-15 Delft Instruments Intellectual Property B.V. Needle assembly for brachytherapy
US5928130A (en) * 1998-03-16 1999-07-27 Schmidt; Bruno Apparatus and method for implanting radioactive seeds in tissue
US6210316B1 (en) * 1998-08-12 2001-04-03 Syntheon, Llc Radioactive therapeutic seeds and methods of making the same
US20020049411A1 (en) * 2000-10-25 2002-04-25 Lamoureux Gary A. Pre-loaded needle assembly
WO2002034325A1 (en) * 2000-10-20 2002-05-02 Imagyn Medical Technologies, Inc. Brachytherapy seed deployment system
US6402677B1 (en) * 1999-12-17 2002-06-11 C.R. Bard, Inc. Brachytherapy seed needle with window
US6419621B1 (en) * 1997-10-24 2002-07-16 Radiomed Corporation Coiled brachytherapy device
US6450937B1 (en) * 1999-12-17 2002-09-17 C. R. Bard, Inc. Needle for implanting brachytherapy seeds

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1867624A (en) * 1930-04-01 1932-07-19 Memorial Hospital For The Trea Device for obtaining biopsy specimens
US4402308A (en) * 1980-11-03 1983-09-06 Scott Walter P Medical implantation device
US4697575A (en) * 1984-11-21 1987-10-06 Henry Ford Hospital Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member
US5141487A (en) * 1985-09-20 1992-08-25 Liprie Sam F Attachment of radioactive source and guidewire in a branchy therapy source wire
US4700692A (en) * 1985-12-23 1987-10-20 Baumgartner George C Surgical implantation method and apparatus
US5267960A (en) * 1990-03-19 1993-12-07 Omnitron International Inc. Tissue engaging catheter for a radioactive source wire
DE9017649U1 (en) * 1990-09-08 1991-06-20 Isotopen-Technik Dr. Sauerwein Gmbh, 5657 Haan, De
US5429582A (en) 1991-06-14 1995-07-04 Williams; Jeffery A. Tumor treatment
US5242373A (en) * 1991-09-17 1993-09-07 Scott Walter P Medical seed implantation instrument
DE4324120A1 (en) * 1993-07-19 1995-01-26 Hauni Werke Koerber & Co Kg Conveyor chain
US5498227A (en) 1993-09-15 1996-03-12 Mawad; Michel E. Retrievable, shielded radiotherapy implant
ATE170708T1 (en) * 1994-06-10 1998-09-15 Schneider Europ Gmbh MEDICINAL DEVICE FOR THE TREATMENT OF A PART OF BODY VESSEL USING IONIZATION RADIATION
US5626829A (en) 1994-11-16 1997-05-06 Pgk, Enterprises, Inc. Method and apparatus for interstitial radiation of the prostate gland
US5906574A (en) * 1995-10-06 1999-05-25 Kan; William C. Apparatus for vacuum-assisted handling and loading of radioactive seeds and spacers into implant needles within an enclosed visible radiation shield for use in therapeutic radioactive seed implantation
US6589502B1 (en) 1995-11-27 2003-07-08 International Brachytherapy S.A. Radioisotope dispersed in a matrix for brachytherapy
DE69530302T2 (en) 1995-12-05 2004-01-29 Schneider Europ Gmbh Buelach A filament for irradiating a living body and a method for producing a filament for irradiating a living body
NL1002044C2 (en) * 1996-01-08 1997-07-09 Optische Ind De Oude Delft Nv Radioactive source that has clinically relevant beta radiation
US6024350A (en) * 1997-01-14 2000-02-15 Black & Decker Inc. Clamp for a power tool
US6030333A (en) * 1997-10-24 2000-02-29 Radiomed Corporation Implantable radiotherapy device
WO1999024117A1 (en) * 1997-11-07 1999-05-20 Global Vascular Concepts, Inc. Device for intravascular delivery of beta emitting isotopes
US6338709B1 (en) * 1998-02-19 2002-01-15 Medtronic Percusurge, Inc. Intravascular radiation therapy device and method of use
US6059767A (en) * 1998-02-25 2000-05-09 Norborn Medical, Inc. Steerable unitary infusion catheter/guide wire incorporating detachable infusion port assembly
US6235001B1 (en) * 1998-05-18 2001-05-22 O'holloran Brian Surgical needle with hand-actuable lock mechanism
US6391026B1 (en) * 1998-09-18 2002-05-21 Pro Duct Health, Inc. Methods and systems for treating breast tissue
US6066083A (en) * 1998-11-27 2000-05-23 Syntheon Llc Implantable brachytherapy device having at least partial deactivation capability
US6270472B1 (en) * 1998-12-29 2001-08-07 University Of Pittsburgh Of The Commonwealth System Of Higher Education Apparatus and a method for automatically introducing implants into soft tissue with adjustable spacing
US6200256B1 (en) * 1999-03-17 2001-03-13 The Trustees Of Columbia University In The City Of New York Apparatus and method to treat a disease process in a luminal structure
US6482178B1 (en) * 1999-05-21 2002-11-19 Cook Urological Incorporated Localization device with anchoring barbs
US6306132B1 (en) * 1999-06-17 2001-10-23 Vivant Medical Modular biopsy and microwave ablation needle delivery apparatus adapted to in situ assembly and method of use
US6221003B1 (en) * 1999-07-26 2001-04-24 Indigo Medical, Incorporated Brachytherapy cartridge including absorbable and autoclaveable spacer
US6264599B1 (en) * 1999-08-10 2001-07-24 Syntheon, Llc Radioactive therapeutic seeds having fixation structure
US6436026B1 (en) * 1999-10-22 2002-08-20 Radiomed Corporation Flexible, continuous, axially elastic interstitial brachytherapy source
US6494835B1 (en) * 2000-02-16 2002-12-17 Jomed Inc. Method and apparatus for intravascular brachytherapy treatment planning
US6572525B1 (en) * 2000-05-26 2003-06-03 Lisa Yoshizumi Needle having an aperture for detecting seeds or spacers loaded therein and colored seeds or spacers
US6497645B1 (en) * 2000-08-28 2002-12-24 Isotron, Inc. Remote afterloader
US6926657B1 (en) * 2000-11-14 2005-08-09 Medi-Physics, Inc. Device for loading radioactive seeds
US6572527B2 (en) * 2001-02-23 2003-06-03 Mentor Corporation Radioactive seed-holding device
US7282020B2 (en) * 2001-04-24 2007-10-16 Microspherix Llc Deflectable implantation device and method of use
US6582354B2 (en) * 2001-07-23 2003-06-24 Real World Design And Development Co. Apparatus for loading radioactive seeds and spacing elements into a brachytherapy needle
US7025717B2 (en) * 2001-08-02 2006-04-11 Bard Brachytherapy, Inc. Semi-automatic needle loader
US6652442B2 (en) * 2002-04-23 2003-11-25 Acueity, Inc. Micro-endoscope assembly for intraductal brachytherapy of a mammary duct and method of using same
DE60324448D1 (en) * 2002-09-10 2008-12-11 Cianna Medical Inc brachytherapy

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5322499A (en) * 1985-09-20 1994-06-21 Liprie Sam F Continuous sheated low dose radioactive core adapted for cutting into short sealed segments
WO1998001179A1 (en) * 1996-07-08 1998-01-15 Delft Instruments Intellectual Property B.V. Needle assembly for brachytherapy
US6419621B1 (en) * 1997-10-24 2002-07-16 Radiomed Corporation Coiled brachytherapy device
US5928130A (en) * 1998-03-16 1999-07-27 Schmidt; Bruno Apparatus and method for implanting radioactive seeds in tissue
US6210316B1 (en) * 1998-08-12 2001-04-03 Syntheon, Llc Radioactive therapeutic seeds and methods of making the same
US6402677B1 (en) * 1999-12-17 2002-06-11 C.R. Bard, Inc. Brachytherapy seed needle with window
US6450937B1 (en) * 1999-12-17 2002-09-17 C. R. Bard, Inc. Needle for implanting brachytherapy seeds
WO2002034325A1 (en) * 2000-10-20 2002-05-02 Imagyn Medical Technologies, Inc. Brachytherapy seed deployment system
US20020049411A1 (en) * 2000-10-25 2002-04-25 Lamoureux Gary A. Pre-loaded needle assembly

Also Published As

Publication number Publication date
WO2004033038A2 (en) 2004-04-22
EP1549397A2 (en) 2005-07-06
US7041047B2 (en) 2006-05-09
CA2510564A1 (en) 2004-04-22
AU2003272825A1 (en) 2004-05-04
US20040068157A1 (en) 2004-04-08

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