WO2004033041A8 - Method and apparatus for target position verification - Google Patents

Method and apparatus for target position verification

Info

Publication number
WO2004033041A8
WO2004033041A8 PCT/US2003/031575 US0331575W WO2004033041A8 WO 2004033041 A8 WO2004033041 A8 WO 2004033041A8 US 0331575 W US0331575 W US 0331575W WO 2004033041 A8 WO2004033041 A8 WO 2004033041A8
Authority
WO
WIPO (PCT)
Prior art keywords
target
treatment plan
therapy device
radiation therapy
radiation treatment
Prior art date
Application number
PCT/US2003/031575
Other languages
French (fr)
Other versions
WO2004033041A1 (en
Inventor
John David Scherch
Original Assignee
Nomos Corp
John David Scherch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nomos Corp, John David Scherch filed Critical Nomos Corp
Priority to JP2004543377A priority Critical patent/JP2006501948A/en
Priority to AU2003282690A priority patent/AU2003282690B2/en
Priority to EP20030774575 priority patent/EP1551510A1/en
Publication of WO2004033041A1 publication Critical patent/WO2004033041A1/en
Publication of WO2004033041A8 publication Critical patent/WO2004033041A8/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42Details of probe positioning or probe attachment to the patient
    • A61B8/4245Details of probe positioning or probe attachment to the patient involving determining the position of the probe, e.g. with respect to an external reference frame or to the patient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1049Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42Details of probe positioning or probe attachment to the patient
    • A61B8/4245Details of probe positioning or probe attachment to the patient involving determining the position of the probe, e.g. with respect to an external reference frame or to the patient
    • A61B8/4263Details of probe positioning or probe attachment to the patient involving determining the position of the probe, e.g. with respect to an external reference frame or to the patient using sensors not mounted on the probe, e.g. mounted on an external reference frame

Abstract

Alignment system for use by a user with a radiation therapy device and a radiation treatment plan for treating a target within a body of a patient and for aligning a position of the target within the body of the patient to a predeter mined position used in the development of the radiation treatment plan. An embodiment of the present invention includes an ultrasound probe for generating live ultrasound images of the target, a position sensing system preferably including a 3-D digitizer articulated arm for indicating the position of the ultrasound probe with respect to the radiation therapy device, adapted to provide a reference location of the target with respect to the radiation therapy device, and a computer having memory and a monitor with a screen associated therewith, and a radiation treatment plan stored in the memory.
PCT/US2003/031575 2002-10-07 2003-10-07 Method and apparatus for target position verification WO2004033041A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2004543377A JP2006501948A (en) 2002-10-07 2003-10-07 Method and apparatus for target position verification
AU2003282690A AU2003282690B2 (en) 2002-10-07 2003-10-07 Method and apparatus for target position verification
EP20030774575 EP1551510A1 (en) 2002-10-07 2003-10-07 Method and apparatus for target position verification

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US41663502P 2002-10-07 2002-10-07
US60/416,635 2002-10-07
US10/680,327 US6961405B2 (en) 2002-10-07 2003-10-07 Method and apparatus for target position verification
US10/680,327 2003-10-07

Publications (2)

Publication Number Publication Date
WO2004033041A1 WO2004033041A1 (en) 2004-04-22
WO2004033041A8 true WO2004033041A8 (en) 2004-07-29

Family

ID=32096155

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/031575 WO2004033041A1 (en) 2002-10-07 2003-10-07 Method and apparatus for target position verification

Country Status (6)

Country Link
US (1) US6961405B2 (en)
EP (1) EP1551510A1 (en)
JP (1) JP2006501948A (en)
KR (1) KR20050059245A (en)
AU (1) AU2003282690B2 (en)
WO (1) WO2004033041A1 (en)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8406844B2 (en) * 2002-03-06 2013-03-26 Tomotherapy Incorporated Method for modification of radiotherapy treatment delivery
US8221322B2 (en) 2002-06-07 2012-07-17 Verathon Inc. Systems and methods to improve clarity in ultrasound images
US8221321B2 (en) 2002-06-07 2012-07-17 Verathon Inc. Systems and methods for quantification and classification of fluids in human cavities in ultrasound images
GB2391625A (en) 2002-08-09 2004-02-11 Diagnostic Ultrasound Europ B Instantaneous ultrasonic echo measurement of bladder urine volume with a limited number of ultrasound beams
US7819806B2 (en) 2002-06-07 2010-10-26 Verathon Inc. System and method to identify and measure organ wall boundaries
CA2518769C (en) * 2003-03-11 2012-07-17 C. Norman Coleman Apparatus and process for dose-guided radiotherapy
WO2005008601A2 (en) * 2003-07-22 2005-01-27 Sgdl Systemes Inc. Acquisition method and apparatus for generating m-degree forms in a n-dimension space
US8055323B2 (en) 2003-08-05 2011-11-08 Imquant, Inc. Stereotactic system and method for defining a tumor treatment region
CA2749057A1 (en) 2004-02-20 2005-09-09 University Of Florida Research Foundation, Inc. System for delivering conformal radiation therapy while simultaneously imaging soft tissue
US10195464B2 (en) * 2004-06-24 2019-02-05 Varian Medical Systems, Inc. Systems and methods for treating a lung of a patient using guided radiation therapy or surgery
US7729472B2 (en) 2004-12-06 2010-06-01 Best Medical International, Inc. System for analyzing the geometry of a radiation treatment apparatus, software and related methods
GB2421572A (en) * 2004-12-22 2006-06-28 Elekta Ab Radiotherapeutic apparatus
US7590218B2 (en) 2005-03-23 2009-09-15 Best Medical International, Inc. System for monitoring the geometry of a radiation treatment apparatus, trackable assembly, program product, and related methods
US8077936B2 (en) * 2005-06-02 2011-12-13 Accuray Incorporated Treatment planning software and corresponding user interface
US11259870B2 (en) 2005-06-06 2022-03-01 Intuitive Surgical Operations, Inc. Interactive user interfaces for minimally invasive telesurgical systems
EP2289454B1 (en) * 2005-06-06 2020-03-25 Intuitive Surgical Operations, Inc. Laparoscopic ultrasound robotic surgical system
US7613501B2 (en) * 2005-06-16 2009-11-03 Best Medical International, Inc. System, tracker, and program product to facilitate and verify proper target alignment for radiation delivery, and related methods
US8442287B2 (en) 2005-07-22 2013-05-14 Tomotherapy Incorporated Method and system for evaluating quality assurance criteria in delivery of a treatment plan
EP2532386A3 (en) 2005-07-22 2013-02-20 TomoTherapy, Inc. System for delivering radiation therapy to a moving region of interest
CA2616293A1 (en) 2005-07-23 2007-02-01 Tomotherapy Incorporated Radiation therapy imaging and delivery utilizing coordinated motion of gantry and couch
US7862512B2 (en) * 2005-08-29 2011-01-04 Unex Corporation Blood vessel endothelium function evaluating apparatus provided with an electronic control device
US20080219405A1 (en) * 2005-09-06 2008-09-11 Tony Falco System and method for patient setup for radiotherapy treatment
WO2007035798A2 (en) 2005-09-19 2007-03-29 Calypso Medical Technologies, Inc. Apparatus and methods for implanting objects, such as bronchoscopically implanting markers in the lung of patients
US7453984B2 (en) * 2006-01-19 2008-11-18 Carestream Health, Inc. Real-time target confirmation for radiation therapy
US8155729B1 (en) * 2006-02-17 2012-04-10 General Electric Company Method and apparatus to compensate imaging data with simultaneously acquired motion data
US9451928B2 (en) * 2006-09-13 2016-09-27 Elekta Ltd. Incorporating internal anatomy in clinical radiotherapy setups
US7890155B2 (en) * 2007-01-04 2011-02-15 Siemens Medical Solutions Usa, Inc. Feature emphasis and contextual cutaways for image visualization
US20080177279A1 (en) * 2007-01-09 2008-07-24 Cyberheart, Inc. Depositing radiation in heart muscle under ultrasound guidance
CN101610719B (en) * 2007-02-07 2014-02-26 皇家飞利浦电子股份有限公司 Motion estimation in treatment planning
US20080317204A1 (en) 2007-03-16 2008-12-25 Cyberheart, Inc. Radiation treatment planning and delivery for moving targets in the heart
US10974075B2 (en) 2007-03-16 2021-04-13 Varian Medical Systems, Inc. Radiation treatment planning and delivery for moving targets in the heart
US8167803B2 (en) 2007-05-16 2012-05-01 Verathon Inc. System and method for bladder detection using harmonic imaging
US9173638B2 (en) * 2007-06-04 2015-11-03 Biosense Webster, Inc. Cardiac mechanical assessment using ultrasound
US8249317B2 (en) * 2007-07-20 2012-08-21 Eleckta Ltd. Methods and systems for compensating for changes in anatomy of radiotherapy patients
WO2009012576A1 (en) * 2007-07-20 2009-01-29 Resonant Medical Inc. Methods and systems for guiding the acquisition of ultrasound images
US8135198B2 (en) * 2007-08-08 2012-03-13 Resonant Medical, Inc. Systems and methods for constructing images
US20090048515A1 (en) * 2007-08-14 2009-02-19 Suri Jasjit S Biopsy planning system
JP5737823B2 (en) * 2007-09-03 2015-06-17 株式会社日立メディコ Ultrasonic diagnostic equipment
CA2751629C (en) * 2007-10-19 2016-08-23 Metritrack, Llc Three dimensional mapping display system for diagnostic ultrasound machines and method
WO2009055775A2 (en) * 2007-10-25 2009-04-30 Tomotherapy Incorporated Method for adapting fractionation of a radiation therapy dose
US8509383B2 (en) * 2007-10-25 2013-08-13 Tomotherapy Incorporated System and method for motion adaptive optimization for radiation therapy delivery
US8467497B2 (en) * 2007-10-25 2013-06-18 Tomotherapy Incorporated System and method for motion adaptive optimization for radiation therapy delivery
US10568535B2 (en) * 2008-05-22 2020-02-25 The Trustees Of Dartmouth College Surgical navigation with stereovision and associated methods
US9052384B2 (en) * 2008-05-22 2015-06-09 The Trustees Of Dartmouth College System and method for calibration for image-guided surgery
US11690558B2 (en) * 2011-01-21 2023-07-04 The Trustees Of Dartmouth College Surgical navigation with stereovision and associated methods
US8189738B2 (en) * 2008-06-02 2012-05-29 Elekta Ltd. Methods and systems for guiding clinical radiotherapy setups
US20110144500A1 (en) * 2008-07-22 2011-06-16 Hitachi Medical Corporation Ultrasonic diagnostic apparatus and method for calculating coordinates of scanned surface thereof
WO2010017508A1 (en) 2008-08-07 2010-02-11 Verathon Inc. Device, system, and method to measure abdominal aortic aneurysm diameter
US8803910B2 (en) * 2008-08-28 2014-08-12 Tomotherapy Incorporated System and method of contouring a target area
JP2010094154A (en) * 2008-10-14 2010-04-30 Toshiba Corp Collation device and radiotherapeutic system
EP2403600A4 (en) * 2009-03-03 2012-08-29 Tomotherapy Inc System and method of optimizing a heterogeneous radiation dose to be delivered to a patient
US10542962B2 (en) * 2009-07-10 2020-01-28 Elekta, LTD Adaptive radiotherapy treatment using ultrasound
CN102510735A (en) 2009-07-17 2012-06-20 计算机心脏股份有限公司 Heart treatment kit, system, and method for radiosurgically alleviating arrhythmia
EP2277593A1 (en) * 2009-07-23 2011-01-26 Siemens Schweiz AG Device for supervising a beam target on an in-vivo zone
WO2011053802A2 (en) * 2009-10-30 2011-05-05 Tomotherapy Incorporated Non-voxel-based broad-beam (nvbb) algorithm for intensity modulated radiation therapy dose calculation and plan optimization
WO2011063517A1 (en) * 2009-11-27 2011-06-03 Sentinelle Medical Inc. Systems and methods for tracking positions between imaging modalities and transforming a displayed three-dimensional image corresponding to a position and orientation of a probe
FR2953119B1 (en) * 2009-12-01 2012-07-27 Gen Electric MOBILE BASE AND X-RAY APPARATUS MOUNTED ON SUCH A MOBILE BASE
US20110172526A1 (en) 2010-01-12 2011-07-14 Martin Lachaine Feature Tracking Using Ultrasound
US9248316B2 (en) 2010-01-12 2016-02-02 Elekta Ltd. Feature tracking using ultrasound
US20110245632A1 (en) * 2010-04-05 2011-10-06 MobiSante Inc. Medical Diagnosis Using Biometric Sensor Protocols Based on Medical Examination Attributes and Monitored Data
EP2390681A3 (en) * 2010-05-31 2014-03-05 Samsung Medison Co., Ltd. 3D ultrasound system and method for operating 3D ultrasound system
US9076310B2 (en) * 2010-07-30 2015-07-07 Lg Electronics Inc. Method and electronic device for remote diagnosis
WO2012015093A1 (en) * 2010-07-30 2012-02-02 엘지전자 주식회사 Method and electronic device for remote diagnosis
WO2012019162A1 (en) 2010-08-06 2012-02-09 Accuray, Inc. Systems and methods for real-time tumor tracking during radiation treatment using ultrasound imaging
US8315356B2 (en) * 2010-09-17 2012-11-20 Accuray Incorporated Image alignment
JP6160000B2 (en) 2010-10-01 2017-07-12 ヴァリアン メディカル システムズ インコーポレイテッド Delivery catheter for delivering grafts, for example for bronchoscopic implantation of markers in the lung
US11109835B2 (en) 2011-12-18 2021-09-07 Metritrack Llc Three dimensional mapping display system for diagnostic ultrasound machines
US11510600B2 (en) 2012-01-04 2022-11-29 The Trustees Of Dartmouth College Method and apparatus for quantitative and depth resolved hyperspectral fluorescence and reflectance imaging for surgical guidance
AU2016208372A1 (en) * 2012-05-02 2016-08-18 Viewray Technologies, Inc. Videographic display of real-time medical treatment
US10561861B2 (en) * 2012-05-02 2020-02-18 Viewray Technologies, Inc. Videographic display of real-time medical treatment
US8750568B2 (en) 2012-05-22 2014-06-10 Covidien Lp System and method for conformal ablation planning
US9439623B2 (en) 2012-05-22 2016-09-13 Covidien Lp Surgical planning system and navigation system
US9498182B2 (en) 2012-05-22 2016-11-22 Covidien Lp Systems and methods for planning and navigation
US9439627B2 (en) 2012-05-22 2016-09-13 Covidien Lp Planning system and navigation system for an ablation procedure
US9439622B2 (en) 2012-05-22 2016-09-13 Covidien Lp Surgical navigation system
US9597529B2 (en) * 2012-09-05 2017-03-21 Best Medical International, Inc. Rapid range stacking (RRS) for particle beam therapy
EP2722012B1 (en) * 2012-10-18 2015-06-03 Storz Medical AG Device for shock wave treatment of the human brain
US9443633B2 (en) 2013-02-26 2016-09-13 Accuray Incorporated Electromagnetically actuated multi-leaf collimator
GB2522914A (en) * 2014-02-10 2015-08-12 Elekta Ab Image guided radiotherapy
US10043284B2 (en) 2014-05-07 2018-08-07 Varian Medical Systems, Inc. Systems and methods for real-time tumor tracking
US9919165B2 (en) 2014-05-07 2018-03-20 Varian Medical Systems, Inc. Systems and methods for fiducial to plan association
US9955889B2 (en) * 2014-11-03 2018-05-01 Biosense Webster (Israel) Ltd. Registration maps using intra-cardiac signals
US10824315B2 (en) * 2015-05-29 2020-11-03 Canon Medical Systems Corporation Medical image processing apparatus, magnetic resonance imaging apparatus and medical image processing method
EP3310437B1 (en) * 2015-06-19 2020-04-01 Koninklijke Philips N.V. Ultrasound guided radiotherapy system
EP3324852A1 (en) * 2015-07-17 2018-05-30 Koninklijke Philips N.V. Guidance for lung cancer radiation
US20190015076A1 (en) * 2015-12-21 2019-01-17 Koninklijke Philips N.V. Ultrasound imaging apparatus and ultrasound imaging method for inspecting a volume of a subject
US10065049B2 (en) * 2016-01-25 2018-09-04 Accuray Incorporated Presenting a sequence of images associated with a motion model
KR20180120705A (en) 2016-03-02 2018-11-06 뷰레이 테크놀로지스 인크. Particle therapy using magnetic resonance imaging
JP6668902B2 (en) * 2016-04-12 2020-03-18 株式会社島津製作所 Positioning device and method of operating positioning device
JP6676780B2 (en) * 2016-04-28 2020-04-08 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. Provide image guided therapy
CA3046091A1 (en) 2016-12-13 2018-06-21 Viewray Technologies, Inc. Radiation therapy systems and methods
US20180308247A1 (en) 2017-04-25 2018-10-25 Best Medical International, Inc. Tissue imaging system and method for tissue imaging
US10183179B1 (en) * 2017-07-21 2019-01-22 Varian Medical Systems, Inc. Triggered treatment systems and methods
WO2019112880A1 (en) 2017-12-06 2019-06-13 Viewray Technologies, Inc. Optimization of multimodal radiotherapy
US11209509B2 (en) 2018-05-16 2021-12-28 Viewray Technologies, Inc. Resistive electromagnet systems and methods
EP3833290A1 (en) 2018-08-10 2021-06-16 Covidien LP Systems for ablation visualization
WO2020172156A1 (en) * 2019-02-18 2020-08-27 Butterfly Network, Inc. Methods and apparatuses enabling a user to manually modify input to a calculation relative to an ultrasound image
CN114271856B (en) * 2021-12-27 2022-10-11 开普云信息科技股份有限公司 Three-dimensional ultrasonic image generation method and device, storage medium and equipment

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6405072B1 (en) * 1991-01-28 2002-06-11 Sherwood Services Ag Apparatus and method for determining a location of an anatomical target with reference to a medical apparatus
US5596619A (en) * 1992-08-21 1997-01-21 Nomos Corporation Method and apparatus for conformal radiation therapy
US5411026A (en) * 1993-10-08 1995-05-02 Nomos Corporation Method and apparatus for lesion position verification
US5622187A (en) * 1994-09-30 1997-04-22 Nomos Corporation Method and apparatus for patient positioning for radiation therapy
US6019724A (en) * 1995-02-22 2000-02-01 Gronningsaeter; Aage Method for ultrasound guidance during clinical procedures
US6256529B1 (en) * 1995-07-26 2001-07-03 Burdette Medical Systems, Inc. Virtual reality 3D visualization for surgical procedures
US5810007A (en) * 1995-07-26 1998-09-22 Associates Of The Joint Center For Radiation Therapy, Inc. Ultrasound localization and image fusion for the treatment of prostate cancer
WO1998017349A1 (en) * 1996-10-24 1998-04-30 Nomos Corporation Planning method and apparatus for radiation dosimetry
US6325758B1 (en) * 1997-10-27 2001-12-04 Nomos Corporation Method and apparatus for target position verification
US6393096B1 (en) * 1998-05-27 2002-05-21 Nomos Corporation Planning method and apparatus for radiation dosimetry
US6438401B1 (en) * 2000-04-28 2002-08-20 Alpha Intervention Technology, Inc. Indentification and quantification of needle displacement departures from treatment plan

Also Published As

Publication number Publication date
AU2003282690A1 (en) 2004-05-04
EP1551510A1 (en) 2005-07-13
US20050020917A1 (en) 2005-01-27
JP2006501948A (en) 2006-01-19
US6961405B2 (en) 2005-11-01
KR20050059245A (en) 2005-06-17
WO2004033041A1 (en) 2004-04-22
AU2003282690B2 (en) 2008-12-18

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