WO2004037186A8 - Prophylactic treatment methods - Google Patents

Prophylactic treatment methods

Info

Publication number
WO2004037186A8
WO2004037186A8 PCT/US2003/033431 US0333431W WO2004037186A8 WO 2004037186 A8 WO2004037186 A8 WO 2004037186A8 US 0333431 W US0333431 W US 0333431W WO 2004037186 A8 WO2004037186 A8 WO 2004037186A8
Authority
WO
WIPO (PCT)
Prior art keywords
metal
prophylactic treatment
containing material
treatment methods
subject
Prior art date
Application number
PCT/US2003/033431
Other languages
French (fr)
Other versions
WO2004037186A2 (en
WO2004037186A3 (en
Inventor
Scott H Gillis
Paul Schechter
Robert H Demling
Original Assignee
Nucryst Pharm Corp
Scott H Gillis
Paul Schechter
Robert H Demling
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nucryst Pharm Corp, Scott H Gillis, Paul Schechter, Robert H Demling filed Critical Nucryst Pharm Corp
Priority to EP03777778A priority Critical patent/EP1567101A4/en
Priority to CA002500829A priority patent/CA2500829A1/en
Priority to AU2003286575A priority patent/AU2003286575A1/en
Priority to JP2004547005A priority patent/JP2006509738A/en
Publication of WO2004037186A2 publication Critical patent/WO2004037186A2/en
Publication of WO2004037186A8 publication Critical patent/WO2004037186A8/en
Publication of WO2004037186A3 publication Critical patent/WO2004037186A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/36Surgical swabs, e.g. for absorbency or packing body cavities during surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/242Gold; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Prophylactic treatment methods are disclosed. The methods can include contacting an object and/or an area of a subject with a metal-containing material to reduce the occurrence of a condition at the same area or a different area of the subject. The metals containing material can be, for example, an antimicrobial material, an anti-biofilm metal containing material, an antibacterial material, an anti-inflammatory material, an anti-fungal material, an anti-viral material, an anti-cancer material, a pro-apoptosis material, an anti proliferative material, an MMP modulating material, an atomically disordered, crystalline material, and/or a nanocrystalline material. In certain embodiments, the metal-containing material is an atomically disordered, nanocrystalline silver-containing material.
PCT/US2003/033431 2002-10-22 2003-10-22 Prophylactic treatment methods WO2004037186A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP03777778A EP1567101A4 (en) 2002-10-22 2003-10-22 Prophylactic treatment methods
CA002500829A CA2500829A1 (en) 2002-10-22 2003-10-22 Prophylactic treatment methods
AU2003286575A AU2003286575A1 (en) 2002-10-22 2003-10-22 Prophylactic treatment methods
JP2004547005A JP2006509738A (en) 2002-10-22 2003-10-22 Prophylactic treatment

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42016702P 2002-10-22 2002-10-22
US60/420,167 2002-10-22

Publications (3)

Publication Number Publication Date
WO2004037186A2 WO2004037186A2 (en) 2004-05-06
WO2004037186A8 true WO2004037186A8 (en) 2004-07-22
WO2004037186A3 WO2004037186A3 (en) 2004-10-21

Family

ID=32176527

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/033431 WO2004037186A2 (en) 2002-10-22 2003-10-22 Prophylactic treatment methods

Country Status (6)

Country Link
US (1) US20040110738A1 (en)
EP (1) EP1567101A4 (en)
JP (1) JP2006509738A (en)
AU (1) AU2003286575A1 (en)
CA (1) CA2500829A1 (en)
WO (1) WO2004037186A2 (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030180379A1 (en) * 2000-07-27 2003-09-25 Burrell Robert E. Solutions and aerosols of metal-containing compounds
NZ545906A (en) * 2003-05-15 2009-10-30 Kanumuru Rahul Raju Functional transition metal silicates (FTMS) for controlling microbes such as plant pathogens
US8734421B2 (en) 2003-06-30 2014-05-27 Johnson & Johnson Consumer Companies, Inc. Methods of treating pores on the skin with electricity
US9457163B2 (en) * 2004-09-03 2016-10-04 Virginia Commonwealth University Prevention of ventilator associated pneumonia (VAP)
NZ554830A (en) * 2004-10-01 2010-10-29 Univ Rutgers Bismuth flouride based nanocomposites as electrode materials
CN101076317A (en) * 2004-11-01 2007-11-21 瑞拉医药公司 Method of reducing nosocomial infections
WO2006056055A2 (en) * 2004-11-23 2006-06-01 Inernational Bio-Therapeutic Research Inc. Method of delivery of therapeutic metal ions, alloys and salts
US7309353B2 (en) * 2005-04-29 2007-12-18 Medtronic Vascular, Inc. Use of platinum group metals in vascular devices and method of texturing platinum group metals
US20070014830A1 (en) * 2005-06-08 2007-01-18 Tijsma Edze J Drug-releasing sinus stent
US20070110788A1 (en) * 2005-11-14 2007-05-17 Hissong James B Injectable formulation capable of forming a drug-releasing device
CA2630147C (en) * 2005-11-18 2015-08-11 Glanbia Nutritionals (Ireland) Limited Compositions for disrupting and inhibiting reconstitution of wound biofilm
US8273381B1 (en) 2006-04-14 2012-09-25 Auburn University Compositions for and methods of controlling olfactory responses to odorants
US7976873B2 (en) 2006-05-10 2011-07-12 Medtronic Xomed, Inc. Extracellular polysaccharide solvating system for treatment of bacterial ear conditions
US7959943B2 (en) * 2006-05-10 2011-06-14 Medtronics Xomed, Inc. Solvating system and sealant for medical use in the middle or inner ear
US7993675B2 (en) * 2006-05-10 2011-08-09 Medtronic Xomed, Inc. Solvating system and sealant for medical use in the sinuses and nasal passages
US20080014247A1 (en) * 2006-06-30 2008-01-17 Nucryst Pharmaceuticals Metal-containing formulations and methods of use
US20080020060A1 (en) * 2006-07-21 2008-01-24 Williamson Robert R Process for treating rhinitis
US8088095B2 (en) 2007-02-08 2012-01-03 Medtronic Xomed, Inc. Polymeric sealant for medical use
US7520923B2 (en) * 2007-03-22 2009-04-21 Mvp Textiles & Apparel, Inc. Antimicrobial filtration article
DE112008001301T5 (en) 2007-05-14 2010-04-29 Reserach Foundation Of State University Of New York Induction of a physiological dispersion response in bacterial cells in a biofilm
US8637094B2 (en) * 2007-07-18 2014-01-28 Iraj E. Kiani Composition and method for treating viral conditions
US7850998B2 (en) * 2007-07-18 2010-12-14 Kiani Iraj E Method of treating viral conditions
US7700137B1 (en) * 2007-07-18 2010-04-20 Kiani Iraj E Anti-viral compositions and method
ES2319064B1 (en) * 2007-10-05 2010-02-15 Universidad De Santiago De Compostela USE OF ATOMIC QUANTIC CLUSTERS (AQCS) AS ANTIMICROBIALS AND BIOCIDES.
CA2727432C (en) 2008-06-12 2016-10-11 Medtronic Xomed, Inc. Method for treating chronic wounds with an extracellular polymeric substance solvating system
DE202008014500U1 (en) * 2008-10-31 2009-01-22 Schreiber, Monika Christine Animal feed for animals
US20120089232A1 (en) 2009-03-27 2012-04-12 Jennifer Hagyoung Kang Choi Medical devices with galvanic particulates
JP5837288B2 (en) * 2010-07-15 2015-12-24 株式会社Nbcメッシュテック Antiviral agent
JP2013123450A (en) * 2011-12-13 2013-06-24 Akihiro Sato Medical treatment method of pneumoconiosis to which metal complex ion liquid is applied, and medical treatment method of pharynx, trachea and bronchus
WO2016040785A1 (en) * 2014-09-12 2016-03-17 K10 Technologies, Inc. Compositions and methods for treating and preventing bacterial infections
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance

Family Cites Families (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3918446A (en) * 1974-05-03 1975-11-11 E Med Corp Securement device for intravenous catheter and its tubing
US4059105A (en) * 1976-03-24 1977-11-22 Omnimed, Inc. Cannula securing device
DE2929706C2 (en) * 1979-07-21 1982-09-30 Drägerwerk AG, 2400 Lübeck Breathing air humidifiers and warmers for ventilation systems
US4393048A (en) * 1980-02-15 1983-07-12 The United States Of America As Represented By The Secretary Of The Army Protective gel composition for wounds
US4324237A (en) * 1980-02-26 1982-04-13 E-Med Corporation Intravenous catheter and tubing securement and dressing device with a window over the puncture or wound site
US4476590A (en) * 1980-03-27 1984-10-16 National Research Development Corporation Antimicrobial surgical implants
US4376764A (en) * 1981-08-10 1983-03-15 Basf Wyandotte Corporation Silver ion gel compositions
US4828832A (en) * 1983-09-07 1989-05-09 Laboratorios Biochemie De Mexico Method of manufacturing a composition for treating skin lesions
US4581028A (en) * 1984-04-30 1986-04-08 The Trustees Of Columbia University In The City Of New York Infection-resistant materials and method of making same through use of sulfonamides
GB8421706D0 (en) * 1984-08-28 1984-10-03 Pharmaceutical Holdings Ltd Pharmaceutical preparations
US4596556A (en) * 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
US4633863A (en) * 1985-09-27 1987-01-06 Filips Chester P Arterial anchor bandage
US4960413A (en) * 1985-11-09 1990-10-02 The Shirley Institute Wound dressing
US5122418A (en) * 1985-12-09 1992-06-16 Shiseido Company Ltd. Composite powder and production process
US4847049A (en) * 1985-12-18 1989-07-11 Vitaphore Corporation Method of forming chelated collagen having bactericidal properties
GB8607159D0 (en) * 1986-03-22 1986-04-30 Smith & Nephew Ass Pharmaceutical composition
US5236421A (en) * 1986-05-28 1993-08-17 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Fixing system for fastening catheters, cannulas or the like to the skin surface and process for the sterile fastening thereof
US4952411A (en) * 1987-02-25 1990-08-28 Trustees Of Columbia University In The City Of New York Method of inhibiting the transmission of AIDS virus
US4790824A (en) * 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US5143717A (en) * 1987-12-30 1992-09-01 Code Blue Medical Corporation Burn foam and delivery system
US5019096A (en) * 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
US4908355A (en) * 1989-01-09 1990-03-13 Dow Corning Corporation Skin treatment method
US5312335A (en) * 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5064413A (en) * 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5270358A (en) * 1989-12-28 1993-12-14 Minnesota Mining And Manufacturing Company Composite of a disperesed gel in an adhesive matrix
IT1238078B (en) * 1990-01-31 1993-07-05 Silvano Spinelli CIS-PLATINUM COMPLEXES WITH AMINES AND CHELANTS SULFINYLCARBOSSILATES
US5348799A (en) * 1991-09-03 1994-09-20 Minnesota Mining And Manufacturing Company Antistatic coatings comprising chitosan acid salt and metal oxide particles
US5240914A (en) * 1992-02-03 1993-08-31 Adolph Schwimmer Method and compositions for inhibiting tumor cell metabolism
GEP20002074B (en) * 1992-05-19 2000-05-10 Westaim Tech Inc Ca Modified Material and Method for its Production
US5681575A (en) * 1992-05-19 1997-10-28 Westaim Technologies Inc. Anti-microbial coating for medical devices
USD349958S (en) * 1992-07-24 1994-08-23 Bioject Inc. Needleless injector
US5383851A (en) * 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
JP2981528B2 (en) * 1992-12-25 1999-11-22 三菱電機株式会社 Cathode ray tube and method of manufacturing the same
US5631066A (en) * 1993-01-25 1997-05-20 Chronopol, Inc. Process for making metalized films and films produced therefrom
US5534288A (en) * 1993-03-23 1996-07-09 United States Surgical Corporation Infection-resistant surgical devices and methods of making them
US5848995A (en) * 1993-04-09 1998-12-15 Walder; Anthony J. Anti-infective medical article and method for its preparation
US5454889A (en) * 1993-08-19 1995-10-03 Ici Canada Inc. Prill coating
EP0727427A4 (en) * 1993-11-05 1997-10-15 Meiji Milk Prod Co Ltd Antibacterial, antifungal and antiviral agent
US5454886A (en) * 1993-11-18 1995-10-03 Westaim Technologies Inc. Process of activating anti-microbial materials
US5372589A (en) * 1993-11-24 1994-12-13 Davis; W. Gordon Fenestrated transparent catheter securing device and method
US5817325A (en) * 1996-10-28 1998-10-06 Biopolymerix, Inc. Contact-killing antimicrobial devices
ATE281075T1 (en) * 1994-03-28 2004-11-15 Univ Columbia COMPOSITION FOR INACTIVATE IRRITANTS IN LIQUIDS
US5899880A (en) * 1994-04-08 1999-05-04 Powderject Research Limited Needleless syringe using supersonic gas flow for particle delivery
US5563132A (en) * 1994-06-21 1996-10-08 Bodaness; Richard S. Two-step cancer treatment method
US5578073A (en) * 1994-09-16 1996-11-26 Ramot Of Tel Aviv University Thromboresistant surface treatment for biomaterials
US5569207A (en) * 1994-10-13 1996-10-29 Quinton Instrument Company Hydrocolloid dressing
GB9424562D0 (en) * 1994-12-06 1995-01-25 Giltech Ltd Product
US5589177A (en) * 1994-12-06 1996-12-31 Helene Curtis, Inc. Rinse-off water-in-oil-in-water compositions
GB9502879D0 (en) * 1995-02-14 1995-04-05 Oxford Biosciences Ltd Particle delivery
DE69638173D1 (en) * 1995-06-07 2010-06-10 Robert S Neuwirth METHOD AND MEANS FOR INTRAUTERINE NECROSATION
US5744151A (en) * 1995-06-30 1998-04-28 Capelli; Christopher C. Silver-based pharmaceutical compositions
US6013050A (en) * 1995-10-20 2000-01-11 Powderject Research Limited Particle delivery
EP0928206B1 (en) * 1996-07-11 2004-04-14 Coloplast A/S A hydrocolloid wound gel
US5895419A (en) * 1996-09-30 1999-04-20 St. Jude Medical, Inc. Coated prosthetic cardiac device
DE19640365A1 (en) * 1996-09-30 1998-04-02 Basf Ag Polymer-hydrogen peroxide complexes
EP1007308B1 (en) * 1997-02-24 2003-11-12 Superior Micropowders LLC Aerosol method and apparatus, particulate products, and electronic devices made therefrom
US6333093B1 (en) * 1997-03-17 2001-12-25 Westaim Biomedical Corp. Anti-microbial coatings having indicator properties and wound dressings
GB2324732B (en) * 1997-05-02 2001-09-26 Johnson & Johnson Medical Absorbent wound dressings
US6071543A (en) * 1997-06-02 2000-06-06 Cellegy Pharmaceuticals, Inc. Pyridine-thiols reverse mucocutaneous aging
KR20010013377A (en) * 1997-06-04 2001-02-26 데이비드 엠 모이어 Mild, leave-on antimicrobial compositions
EP0991702B2 (en) * 1997-06-20 2017-07-19 Coloplast A/S A hydrophilic coating
US6165440A (en) * 1997-07-09 2000-12-26 Board Of Regents, The University Of Texas System Radiation and nanoparticles for enhancement of drug delivery in solid tumors
US6123925A (en) * 1998-07-27 2000-09-26 Healthshield Technologies L.L.C. Antibiotic toothpaste
US6071541A (en) * 1998-07-31 2000-06-06 Murad; Howard Pharmaceutical compositions and methods for managing skin conditions
US6454754B1 (en) * 1998-10-29 2002-09-24 Steven R. Frank Respiratory infection treatment device
AU776212B2 (en) * 1998-11-09 2004-09-02 Ira Jay Newman Ionic silver complex
US6096002A (en) * 1998-11-18 2000-08-01 Bioject, Inc. NGAS powered self-resetting needle-less hypodermic jet injection apparatus and method
US6365130B1 (en) * 1998-11-23 2002-04-02 Agion Technologies L.L.C. Antimicrobial chewing gum
US6224579B1 (en) * 1999-03-31 2001-05-01 The Trustees Of Columbia University In The City Of New York Triclosan and silver compound containing medical devices
US6258385B1 (en) * 1999-04-22 2001-07-10 Marantech Holding, Llc Tetrasilver tetroxide treatment for skin conditions
US6103272A (en) * 1999-07-15 2000-08-15 Keeney; Joseph A. Compositions for stimulating hair growth, preventing hair loss, or minimizing hair loss, and methods for preparing and using same
JP2001151681A (en) * 1999-11-24 2001-06-05 Lintec Corp Prophylactic and/or therapeutic agent for systema digestorium disease
US6224898B1 (en) * 2000-03-23 2001-05-01 The United States Of America As Represented By The Secretary Of The Army Antimicrobial dendrimer nanocomposites and a method of treating wounds
US6719987B2 (en) * 2000-04-17 2004-04-13 Nucryst Pharmaceuticals Corp. Antimicrobial bioabsorbable materials
JP2004505057A (en) * 2000-07-27 2004-02-19 ニュクリスト ファーマシューティカルズ コーポレーション Treatment of hyperproliferative skin disorders and diseases
US7008647B2 (en) * 2001-04-23 2006-03-07 Nucryst Pharmaceuticals Corp. Treatment of acne
US6989157B2 (en) * 2000-07-27 2006-01-24 Nucryst Pharmaceuticals Corp. Dry powders of metal-containing compounds
DE10037353A1 (en) * 2000-07-29 2002-02-07 Hans E Sachse Catheter with bioabsorbable coating to prevent rising infections
DE60210441T2 (en) * 2001-04-23 2006-11-16 Nucryst Pharmaceuticals Corp., Fort Saskatchewan MEDICAMENT OR PLASTER CONTAINS A METAL SUCH AS SILVER, GOLD, PLATINUM OR PALLADIUM AS AN ANTIMICROBIAL ACTIVE INGREDIENT AND ITS USE IN THE TREATMENT OF SKIN INFUSION
US6899903B2 (en) * 2002-06-25 2005-05-31 Patrick Quillin Composition for cleansing the sinuses

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EP1567101A2 (en) 2005-08-31
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US20040110738A1 (en) 2004-06-10
AU2003286575A1 (en) 2004-05-13
CA2500829A1 (en) 2004-05-06
EP1567101A4 (en) 2009-06-03

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