WO2004038752A3 - Contiguous capillary electrospray sources and analytical device - Google Patents
Contiguous capillary electrospray sources and analytical device Download PDFInfo
- Publication number
- WO2004038752A3 WO2004038752A3 PCT/US2003/033200 US0333200W WO2004038752A3 WO 2004038752 A3 WO2004038752 A3 WO 2004038752A3 US 0333200 W US0333200 W US 0333200W WO 2004038752 A3 WO2004038752 A3 WO 2004038752A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- capillaries
- contiguous
- disclosed
- methods
- analytical device
- Prior art date
Links
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
- B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
- B05B5/0255—Discharge apparatus, e.g. electrostatic spray guns spraying and depositing by electrostatic forces only
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
- B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
- B05B5/053—Arrangements for supplying power, e.g. charging power
- B05B5/0533—Electrodes specially adapted therefor; Arrangements of electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
- H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
- H01J49/165—Electrospray ionisation
- H01J49/167—Capillaries and nozzles specially adapted therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/529,967 US7544932B2 (en) | 2002-10-21 | 2003-10-20 | Contiguous capillary electrospray sources and analytical devices |
AU2003286502A AU2003286502A1 (en) | 2002-10-21 | 2003-10-20 | Contiguous capillary electrospray sources and analytical device |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42000302P | 2002-10-21 | 2002-10-21 | |
US60/420,003 | 2002-10-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004038752A2 WO2004038752A2 (en) | 2004-05-06 |
WO2004038752A3 true WO2004038752A3 (en) | 2004-07-29 |
Family
ID=32176498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/033200 WO2004038752A2 (en) | 2002-10-21 | 2003-10-20 | Contiguous capillary electrospray sources and analytical device |
Country Status (3)
Country | Link |
---|---|
US (1) | US7544932B2 (en) |
AU (1) | AU2003286502A1 (en) |
WO (1) | WO2004038752A2 (en) |
Families Citing this family (15)
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AU2003286502A1 (en) | 2002-10-21 | 2004-05-13 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Contiguous capillary electrospray sources and analytical device |
US7087895B1 (en) * | 2003-06-07 | 2006-08-08 | Musc Foundation For Research Development | Electrospray ionization using pointed fibers |
CA2597321A1 (en) | 2005-02-11 | 2006-08-17 | Battelle Memorial Institute | Ehd aerosol dispensing device and spraying method |
BRPI0806471A2 (en) * | 2007-01-12 | 2011-09-27 | Univ Texas | low flow interface separation techniques |
EP2153455B1 (en) * | 2007-06-01 | 2020-04-29 | PerkinElmer Health Sciences, Inc. | Atmospheric pressure ion source performance enhancement |
US8449746B2 (en) | 2010-07-16 | 2013-05-28 | Waters Technologies Corporation | Systems and methods for coupling molecule separation devices to analytical instruments |
DE102010041433A1 (en) * | 2010-09-27 | 2012-03-29 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Capillary tube for electrophoresis |
US9275844B2 (en) * | 2012-05-16 | 2016-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus and method for nanoflow liquid jet and serial femtosecond x-ray protein crystallography |
US8754370B1 (en) * | 2013-03-07 | 2014-06-17 | Battelle Memorial Institute | Sheathless interface for coupling capillary electrophoresis with mass spectrometry |
WO2014179361A1 (en) * | 2013-04-29 | 2014-11-06 | Birmingham Joseph G | System and method for high-voltage ac-powered electrospray |
WO2016191512A1 (en) | 2015-05-28 | 2016-12-01 | Georgia Tech Research Corporation | Systems and methods of electron beam induced processing |
CN106373856B (en) * | 2015-07-23 | 2019-02-15 | 北京理工大学 | Electric spray ion source and LC-MS connecting interface comprising the ion source |
CN110998786B (en) * | 2017-07-07 | 2023-09-01 | Dh科技发展私人贸易有限公司 | Electrospray interface device and related methods |
US20190019662A1 (en) * | 2017-07-14 | 2019-01-17 | Purdue Research Foundation | Electrophoretic mass spectrometry probes and systems and uses thereof |
CN112834596B (en) * | 2020-12-30 | 2022-08-30 | 武汉大学 | Sheath-flow-free CE-MS interface device based on acrylamide conductive gel and application |
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-
2003
- 2003-10-20 AU AU2003286502A patent/AU2003286502A1/en not_active Abandoned
- 2003-10-20 WO PCT/US2003/033200 patent/WO2004038752A2/en not_active Application Discontinuation
- 2003-10-20 US US10/529,967 patent/US7544932B2/en active Active
Patent Citations (4)
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---|---|---|---|---|
US5245186A (en) * | 1991-11-18 | 1993-09-14 | The Rockefeller University | Electrospray ion source for mass spectrometry |
US5975426A (en) * | 1998-05-14 | 1999-11-02 | Waters Investments Limited | Use of porous beads as a tip for nano-electrospray |
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Non-Patent Citations (2)
Title |
---|
KERTESZ V. ET AL: "Minimizing analyte electrolysis in an electrospray emitter", J. MASS SPECTROMETRY, vol. 36, no. 2, February 2001 (2001-02-01), pages 204 - 210, XP002979051 * |
SHEN Y. ET AL: "High-efficiency nanoscale liquid chromatography coupled on-line with mass spectrometry using nanoelectrospray ionization for proteomics", ANALYTICAL CHEMISTRY, vol. 74, no. 16, 15 August 2002 (2002-08-15), pages 4235 - 4249, XP002979050 * |
Also Published As
Publication number | Publication date |
---|---|
US7544932B2 (en) | 2009-06-09 |
AU2003286502A8 (en) | 2004-05-13 |
WO2004038752A2 (en) | 2004-05-06 |
AU2003286502A1 (en) | 2004-05-13 |
US20060057556A1 (en) | 2006-03-16 |
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