WO2004043333A3 - Bone enhancing composite - Google Patents

Bone enhancing composite Download PDF

Info

Publication number
WO2004043333A3
WO2004043333A3 PCT/IL2003/000962 IL0300962W WO2004043333A3 WO 2004043333 A3 WO2004043333 A3 WO 2004043333A3 IL 0300962 W IL0300962 W IL 0300962W WO 2004043333 A3 WO2004043333 A3 WO 2004043333A3
Authority
WO
WIPO (PCT)
Prior art keywords
composite
enhancing composite
bone
bone enhancing
supplementary bioactive
Prior art date
Application number
PCT/IL2003/000962
Other languages
French (fr)
Other versions
WO2004043333A2 (en
Inventor
Avner Yayon
Original Assignee
Prochon Biotech Ltd
Avner Yayon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL153699A external-priority patent/IL153699A/en
Application filed by Prochon Biotech Ltd, Avner Yayon filed Critical Prochon Biotech Ltd
Priority to US10/534,794 priority Critical patent/US7887831B2/en
Priority to AU2003283785A priority patent/AU2003283785A1/en
Publication of WO2004043333A2 publication Critical patent/WO2004043333A2/en
Publication of WO2004043333A3 publication Critical patent/WO2004043333A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/30Inorganic materials
    • A61L27/32Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2817Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • A61F2310/00293Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite

Abstract

A bone-enhancing composite material comprising synthetic apatite and at least one supplementary bioactive agent selected from a biocompatible polymer and anti-resorption agent added ab initio, methods of preparing said composite and uses thereof are provided. The physical and biological properties of the composite are controlled by the addition of specific supplementary bioactive agents as well as optional therapeutic agents. The composite may be used as a powder, a paste or an implant.
PCT/IL2003/000962 2002-11-14 2003-11-13 Bone enhancing composite WO2004043333A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US10/534,794 US7887831B2 (en) 2002-12-26 2003-11-13 Bone enhancing composite
AU2003283785A AU2003283785A1 (en) 2002-11-14 2003-11-13 Bone enhancing composite

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ILPCT/IL02/00913 2002-11-14
IL0200913 2002-11-14
IL153699 2002-12-26
IL153699A IL153699A (en) 2002-12-26 2002-12-26 Bone graft composite

Publications (2)

Publication Number Publication Date
WO2004043333A2 WO2004043333A2 (en) 2004-05-27
WO2004043333A3 true WO2004043333A3 (en) 2004-07-15

Family

ID=32314004

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2003/000962 WO2004043333A2 (en) 2002-11-14 2003-11-13 Bone enhancing composite

Country Status (2)

Country Link
AU (1) AU2003283785A1 (en)
WO (1) WO2004043333A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7504374B2 (en) * 2000-10-24 2009-03-17 Warsaw Orthopedic, Inc. Method for inducing deposition and maturation of bone comprising a co-therapeutic regimen of LMP-1 and BMP-2
WO2007119240A2 (en) * 2006-04-17 2007-10-25 Hepacore Ltd. Methods for bone regeneration using endothelial progenitor cell preparations
US20100015068A1 (en) * 2006-07-06 2010-01-21 Massachusetts Institute Of Technology Methods and Compositions For Altering Biological Surfaces
WO2014020446A2 (en) * 2012-08-01 2014-02-06 Sandvik Intellectual Property Ab Hydroxyapatite coating process using microwave technology
CN115232304B (en) * 2022-07-26 2023-05-26 四川大学 Bisphosphonate-containing polyamino acid copolymer, bone material for resisting bone tumor and preparation thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770229A (en) * 1994-05-13 1998-06-23 Kuraray Co., Ltd. Medical polymer gel

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770229A (en) * 1994-05-13 1998-06-23 Kuraray Co., Ltd. Medical polymer gel

Also Published As

Publication number Publication date
AU2003283785A8 (en) 2004-06-03
WO2004043333A2 (en) 2004-05-27
AU2003283785A1 (en) 2004-06-03

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