WO2004047714A1 - Multiple-chamber medical container and method for producing the same - Google Patents
Multiple-chamber medical container and method for producing the same Download PDFInfo
- Publication number
- WO2004047714A1 WO2004047714A1 PCT/JP2003/014869 JP0314869W WO2004047714A1 WO 2004047714 A1 WO2004047714 A1 WO 2004047714A1 JP 0314869 W JP0314869 W JP 0314869W WO 2004047714 A1 WO2004047714 A1 WO 2004047714A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- discharge
- chamber
- seal
- medicament
- container body
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2093—Containers having several compartments for products to be mixed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/202—Separating means
- A61J1/2024—Separating means having peelable seals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
- B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
- B29C65/18—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using heated tools
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
- B29C65/76—Making non-permanent or releasable joints
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/05—Particular design of joint configurations
- B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
- B29C66/11—Joint cross-sections comprising a single joint-segment, i.e. one of the parts to be joined comprising a single joint-segment in the joint cross-section
- B29C66/112—Single lapped joints
- B29C66/1122—Single lap to lap joints, i.e. overlap joints
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/05—Particular design of joint configurations
- B29C66/20—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines
- B29C66/21—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines said joint lines being formed by a single dot or dash or by several dots or dashes, i.e. spot joining or spot welding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/05—Particular design of joint configurations
- B29C66/20—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines
- B29C66/24—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines said joint lines being closed or non-straight
- B29C66/244—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines said joint lines being closed or non-straight said joint lines being non-straight, e.g. forming non-closed contours
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/05—Particular design of joint configurations
- B29C66/20—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines
- B29C66/24—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines said joint lines being closed or non-straight
- B29C66/244—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines said joint lines being closed or non-straight said joint lines being non-straight, e.g. forming non-closed contours
- B29C66/2442—Particular design of joint configurations particular design of the joint lines, e.g. of the weld lines said joint lines being closed or non-straight said joint lines being non-straight, e.g. forming non-closed contours in the form of a single arc of circle
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/345—Progressively making the joint, e.g. starting from the middle
- B29C66/3452—Making complete joints by combining partial joints
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/346—Making joints having variable thicknesses in the joint area, e.g. by using jaws having an adapted configuration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/346—Making joints having variable thicknesses in the joint area, e.g. by using jaws having an adapted configuration
- B29C66/3462—Making joints having variable thicknesses in the joint area, e.g. by using jaws having an adapted configuration by differentially heating the zones of different thickness
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/347—General aspects dealing with the joint area or with the area to be joined using particular temperature distributions or gradients; using particular heat distributions or gradients
- B29C66/3472—General aspects dealing with the joint area or with the area to be joined using particular temperature distributions or gradients; using particular heat distributions or gradients in the plane of the joint, e.g. along the joint line in the plane of the joint or perpendicular to the joint line in the plane of the joint
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/40—General aspects of joining substantially flat articles, e.g. plates, sheets or web-like materials; Making flat seams in tubular or hollow articles; Joining single elements to substantially flat surfaces
- B29C66/41—Joining substantially flat articles ; Making flat seams in tubular or hollow articles
- B29C66/43—Joining a relatively small portion of the surface of said articles
- B29C66/431—Joining the articles to themselves
- B29C66/4312—Joining the articles to themselves for making flat seams in tubular or hollow articles, e.g. transversal seams
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
- B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
- B29C66/53—Joining single elements to tubular articles, hollow articles or bars
- B29C66/532—Joining single elements to the wall of tubular articles, hollow articles or bars
- B29C66/5326—Joining single elements to the wall of tubular articles, hollow articles or bars said single elements being substantially flat
- B29C66/53261—Enclosing tubular articles between substantially flat elements
- B29C66/53262—Enclosing spouts between the walls of bags, e.g. of medical bags
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
- B29C66/71—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the composition of the plastics material of the parts to be joined
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
- B29C66/73—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset
- B29C66/739—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of the parts to be joined being a thermoplastic or a thermoset
- B29C66/7392—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of at least one of the parts being a thermoplastic
- B29C66/73921—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of at least one of the parts being a thermoplastic characterised by the materials of both parts being thermoplastics
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/90—Measuring or controlling the joining process
- B29C66/91—Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux
- B29C66/914—Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux by controlling or regulating the temperature, the heat or the thermal flux
- B29C66/9141—Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux by controlling or regulating the temperature, the heat or the thermal flux by controlling or regulating the temperature
- B29C66/91411—Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux by controlling or regulating the temperature, the heat or the thermal flux by controlling or regulating the temperature of the parts to be joined, e.g. the joining process taking the temperature of the parts to be joined into account
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/90—Measuring or controlling the joining process
- B29C66/92—Measuring or controlling the joining process by measuring or controlling the pressure, the force, the mechanical power or the displacement of the joining tools
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2009/00—Layered products
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/712—Containers; Packaging elements or accessories, Packages
- B29L2031/7148—Blood bags, medical bags
Definitions
- multiple-chamber containers as described above have thus far been proposed.
- a typical example of these is a multiple-chamber container made of plastic film and formed in the shape of a bag. Making use of the plastic film, a weak partition seal to separate the chambers from each other is formed in such a container by heat-sealing the facing surfaces of the film.
- the narrowest part of the pathway preferably has a width or diameter of 1 to 5 mm, thereby a free inflow of the liquid medicament from the storage compartment to the middle chamber can be reliably suppressed. Consequently, even if the pathway is formed, quick leakage of the medicament from the storage chamber to the medicament outlet before use can be reliably prevented.
- a weak discharge-control seal (discharge-control seal) 21 is formed between the second storage chamber 11 and the medicament outlet 7 to interrupt the passage of medicament therebetween.
- the weak discharge-control .seal 21 is formed arcwise around the medicament outlet 7 and both ends thereof are connected to the circumference 3 of the container body 5 in proximity to the medicament outlet 7.
- a middle chamber 23 is formed in the shape of semi-circle between the weak partition seal 21 and the medicament outlet 7.
- a pathway 25 having narrow width is arranged at the top part of the arc of weak discharge-control seal 21, and the second storage chamber 11 and the middle chamber 23 communicate with each other via the pathway 25.
- the width of the pathway 25 is preferably 1 to 5 mm so that the gas passage can be allowed between the storage chamber 11 and the middle chamber 23 and the inflow of liquid medicament from the second storage chamber 11 into the middle chamber 23 can be inhibited by the inner pressure of the middle chamber 23.
- the weak discharge-control seal 21 is formed in a similar way to the weak partition seal 13 by heat- sealing the inner surfaces of two facing films of container body 5.
- the weak discharge-control seal 21 is provided in such a manner as to be openable by increasing the inner pressures of the storage chambers 9 and 11, and the opening strength thereof is adjusted to be smaller than that of the weak partition seal 13.
- the weak discharge-control seal 23 is arranged arcwise in the above embodiment, the shape is not particularly limited.
- the weak discharge- control seal may be shaped semi-ellipse, substantially arcwise having squared corners, or linear to link both sides of the container body 5 as shown in FIG. 4.
- the pathway 25 does not necessarily have a uniform width and has only to prevent a passage of liquid. Especially, when the width of the narrowest part is 1 to 5 mm, such effect can be fully achieved.
- the pathway 25 may be provided not only in one position but in two or more positions, as long as a passage of medicament is inhibited. (Second embodiment)
- one of the ends 21a of the weak discharge- control seal 21 may be connected to the lower edge 3a where the medicament outlet 7 is provided, and the other end to the side edge 3b.
- both ends 21a of each weak discharge-control seal 21 have a narrower width in the above, only one of the two ends may also have a narrow width. However, in order to avoid an unopened part reliably, it is preferred to narrow the both ends.
- the width of the weak discharge-control seal 21 is adjusted so that the both ends thereof are easily opened.
- easier opening of the both ends can also be achieved by changing the sealing conditions of the center part and both ends with their width kept same.
- the heat sealing can be carried out with a mold to form the weak discharge-control seal 21, at the sealing temperature of both ends 21a lower than that of the center part 21b.
- the center part 21b can be referred to as a high-temperature sealed part while the both end parts 21a as a low- temperature sealed part.
- the difference in the sealing temperature is preferably 0.3 to 10 °C, and thereby the sealing release strength of both ends 21a can be set smaller than that of the center part 21b.
- “Sealing release strength” denotes the strength that can release the sealed state per unit length in the longitudinal direction of the weak discharge-control seal 21, i.e. the strength at the time the surfaces of two sealed films separate from each other.
- the sealing release strength can be expressed, for example as a peeling strength shown in JIS-Z0238.
- the peeling strength denotes the strength required for separating two film surfaces that are heat-sealed by a weak seal having a width of 15 mm. In this case, it is preferred that the peeling strength of the center part 21b of the weak discharge-control seal 21 is 1 to 7 N/15mm and the peeling strength of its both ends 21a is 25 to 90% of that of the center part.
- the sealing release strength can be adjusted by varying the thickness of the mold. That is, a pair of molds 41 for forming the weak discharge-control seal 21 is provided in such a manner as to consist of the first molds 41a for forming both end parts 21a and the second molds 41b for forming the center part 21b and the second mold 41b is provided thicker than the first mold 41a. Accordingly the distance between the molds is different between the end parts and the center part, and the sealing strength of both end parts 21a having a further distance between the molds becomes smaller when the heat-sealing is carried out. Therefore, the sealing release strength of the both ends 21a can be adjusted smaller than that of the center part 21b.
- the difference in thickness between the first mold 41a and the second mold 41b is preferably 20 to 80 ⁇ m.
- the above-described constitution of the weak discharge-control seal 21 is applicable to the multiple- chamber container of the first embodiment.
- a pathway is provided at the center part of the weak discharge-control seal and the both end parts 21a can be provided as to have a narrower width than that of the center part 21b.
- the pathway shown in the first embodiment can be formed at the weak discharge- control seal shown in FIGs. 6 to 9, where the both end parts 21a are opened more easily than the center part 21b.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005510283A JP4463205B2 (ja) | 2002-11-28 | 2003-11-21 | 医療用複室容器及びその製造方法 |
AU2003282391A AU2003282391A1 (en) | 2002-11-28 | 2003-11-21 | Multiple-chamber medical container and method for producing the same |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002346056 | 2002-11-28 | ||
JP2002-346056 | 2002-11-28 | ||
JP2003003418 | 2003-01-09 | ||
JP2003-003418 | 2003-01-09 |
Publications (2)
Publication Number | Publication Date |
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WO2004047714A1 true WO2004047714A1 (en) | 2004-06-10 |
WO2004047714A8 WO2004047714A8 (en) | 2004-08-05 |
Family
ID=32396294
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2003/014869 WO2004047714A1 (en) | 2002-11-28 | 2003-11-21 | Multiple-chamber medical container and method for producing the same |
Country Status (4)
Country | Link |
---|---|
JP (1) | JP4463205B2 (es) |
AU (1) | AU2003282391A1 (es) |
TW (1) | TWI226234B (es) |
WO (1) | WO2004047714A1 (es) |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005342174A (ja) * | 2004-06-02 | 2005-12-15 | Showa Denko Plastic Products Co Ltd | 医療用薬液容器 |
JP2006006707A (ja) * | 2004-06-28 | 2006-01-12 | Otsuka Pharmaceut Factory Inc | 医療用複室容器及びこれに取り付けられる排出規制部材 |
EP1621177A1 (en) * | 2004-07-29 | 2006-02-01 | Fresenius Kabi Deutschland GmbH | Medical container with improved peelable seal |
JP2006255406A (ja) * | 2005-02-17 | 2006-09-28 | Terumo Corp | 医療用複室容器 |
JP2007014632A (ja) * | 2005-07-08 | 2007-01-25 | Otsuka Pharmaceut Factory Inc | 複室容器 |
WO2007046744A1 (en) * | 2005-10-17 | 2007-04-26 | Gambro Lundia Ab | Multicompartment container containing a medical solution |
JP2007217044A (ja) * | 2006-02-18 | 2007-08-30 | Kusaka Rare Metal Products Co Ltd | 電子レンジ調理用食品包装体 |
US7875016B2 (en) | 2004-07-29 | 2011-01-25 | Fresenius Kabi Deutschland Gmbh | Flexible multi-chamber container for the preparation of medical mixed solutions |
WO2011019347A1 (en) * | 2009-08-12 | 2011-02-17 | Baxter International Inc. | Containers comprising peelable seals |
JP2011131104A (ja) * | 2005-02-17 | 2011-07-07 | Terumo Corp | 医療用複室容器 |
US8048055B2 (en) | 2005-11-07 | 2011-11-01 | Caridianbct Biotechnologies, Llc | Clamp assembly for displacing fluid from portions of fluid containers |
US8668681B2 (en) | 2007-04-27 | 2014-03-11 | Ajinomoto Co., Inc. | Multi-chamber container |
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JP2005342174A (ja) * | 2004-06-02 | 2005-12-15 | Showa Denko Plastic Products Co Ltd | 医療用薬液容器 |
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JP2006006707A (ja) * | 2004-06-28 | 2006-01-12 | Otsuka Pharmaceut Factory Inc | 医療用複室容器及びこれに取り付けられる排出規制部材 |
JP4498030B2 (ja) * | 2004-06-28 | 2010-07-07 | 株式会社大塚製薬工場 | 医療用複室容器及びこれに取り付けられる排出規制部材 |
EP1621177A1 (en) * | 2004-07-29 | 2006-02-01 | Fresenius Kabi Deutschland GmbH | Medical container with improved peelable seal |
EA010347B1 (ru) * | 2004-07-29 | 2008-08-29 | Фрезениус Каби Дойчланд Гмбх | Используемый в медицинских целях контейнер с усовершенствованным разъединяемым герметично изолирующим соединением |
WO2006010411A1 (en) * | 2004-07-29 | 2006-02-02 | Fresenius Kabi Deutschland Gmbh | Medical container with improved peelable seal |
US7875016B2 (en) | 2004-07-29 | 2011-01-25 | Fresenius Kabi Deutschland Gmbh | Flexible multi-chamber container for the preparation of medical mixed solutions |
US7875015B2 (en) | 2004-07-29 | 2011-01-25 | Fresenius Kabi Deutschland Gmbh | Medical container with improved peelable seal |
JP2011131104A (ja) * | 2005-02-17 | 2011-07-07 | Terumo Corp | 医療用複室容器 |
JP2006255406A (ja) * | 2005-02-17 | 2006-09-28 | Terumo Corp | 医療用複室容器 |
JP4594178B2 (ja) * | 2005-07-08 | 2010-12-08 | 株式会社大塚製薬工場 | 複室容器 |
JP2007014632A (ja) * | 2005-07-08 | 2007-01-25 | Otsuka Pharmaceut Factory Inc | 複室容器 |
WO2007046744A1 (en) * | 2005-10-17 | 2007-04-26 | Gambro Lundia Ab | Multicompartment container containing a medical solution |
US8197460B2 (en) | 2005-10-17 | 2012-06-12 | Gambro Lundia Ab | Multicompartment container containing a medical solution |
US8048055B2 (en) | 2005-11-07 | 2011-11-01 | Caridianbct Biotechnologies, Llc | Clamp assembly for displacing fluid from portions of fluid containers |
JP2007217044A (ja) * | 2006-02-18 | 2007-08-30 | Kusaka Rare Metal Products Co Ltd | 電子レンジ調理用食品包装体 |
US8668681B2 (en) | 2007-04-27 | 2014-03-11 | Ajinomoto Co., Inc. | Multi-chamber container |
WO2011019347A1 (en) * | 2009-08-12 | 2011-02-17 | Baxter International Inc. | Containers comprising peelable seals |
US8940228B2 (en) | 2012-01-11 | 2015-01-27 | Terumo Bct, Inc. | Slidable clamp for port isolation |
CN112584814A (zh) * | 2018-08-17 | 2021-03-30 | 美国圣戈班性能塑料公司 | 用于储存药物或生物介质的系统和方法 |
US11865071B2 (en) | 2018-08-17 | 2024-01-09 | Saint-Gobain Performance Plastics Corporation | System and method for storing pharmaceuticals or biological media |
Also Published As
Publication number | Publication date |
---|---|
JP4463205B2 (ja) | 2010-05-19 |
JP2006507914A (ja) | 2006-03-09 |
TWI226234B (en) | 2005-01-11 |
WO2004047714A8 (en) | 2004-08-05 |
TW200412926A (en) | 2004-08-01 |
AU2003282391A1 (en) | 2004-06-18 |
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