WO2004062486A3 - T-wave alternans train spotter - Google Patents

T-wave alternans train spotter Download PDF

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Publication number
WO2004062486A3
WO2004062486A3 PCT/US2004/000729 US2004000729W WO2004062486A3 WO 2004062486 A3 WO2004062486 A3 WO 2004062486A3 US 2004000729 W US2004000729 W US 2004000729W WO 2004062486 A3 WO2004062486 A3 WO 2004062486A3
Authority
WO
WIPO (PCT)
Prior art keywords
alternans
match
values
spotter
train
Prior art date
Application number
PCT/US2004/000729
Other languages
French (fr)
Other versions
WO2004062486A2 (en
Inventor
Matias Rouw
Philppe Debuyne
Groeringen Chritianus J J Van
Original Assignee
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc filed Critical Medtronic Inc
Priority to CA002514876A priority Critical patent/CA2514876A1/en
Priority to EP04701780A priority patent/EP1585443B1/en
Priority to DE602004006228T priority patent/DE602004006228T2/en
Publication of WO2004062486A2 publication Critical patent/WO2004062486A2/en
Publication of WO2004062486A3 publication Critical patent/WO2004062486A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3621—Heart stimulators for treating or preventing abnormally high heart rate
    • A61N1/3622—Heart stimulators for treating or preventing abnormally high heart rate comprising two or more electrodes co-operating with different heart regions

Abstract

A method and system for detecting T-wave alternans for use in an implanted medical device uses wave transformation of QT intervals to obtain a reliable measure of TWA. In one embodiment, an array provides alternating sign multiplication factors which are applied respectively to n consecutive QT values. Each successive QT value is high pass filtered and moved sequentially through a queue so that each cycle each of the n QT values is multiplied by one of the factors; the products are summed and made absolute to provide an alternans match value. The alternans match is compared with a noise threshold signal, and alternans is declared when the match exceeds the threshold by a predetermined amount. The array is programmable and can be varied, providing a high degree of flexibility to optimize the test for the patient.
PCT/US2004/000729 2003-01-13 2004-01-13 T-wave alternans train spotter WO2004062486A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002514876A CA2514876A1 (en) 2003-01-13 2004-01-13 T-wave alternans train spotter
EP04701780A EP1585443B1 (en) 2003-01-13 2004-01-13 T-wave alternans train spotter
DE602004006228T DE602004006228T2 (en) 2003-01-13 2004-01-13 IDENTIFICATION OF ALTERNATIVE T-WAVES

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43945903P 2003-01-13 2003-01-13
US60/439,459 2003-01-13

Publications (2)

Publication Number Publication Date
WO2004062486A2 WO2004062486A2 (en) 2004-07-29
WO2004062486A3 true WO2004062486A3 (en) 2004-09-23

Family

ID=32713486

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/000729 WO2004062486A2 (en) 2003-01-13 2004-01-13 T-wave alternans train spotter

Country Status (5)

Country Link
US (2) US7725172B2 (en)
EP (1) EP1585443B1 (en)
CA (1) CA2514876A1 (en)
DE (1) DE602004006228T2 (en)
WO (1) WO2004062486A2 (en)

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US20060116596A1 (en) * 2004-12-01 2006-06-01 Xiaohong Zhou Method and apparatus for detection and monitoring of T-wave alternans
US7756571B1 (en) 2005-09-16 2010-07-13 Pacesetter, Inc. Methods and systems for detecting the presence of T-wave alternans
US7881792B1 (en) 2005-09-16 2011-02-01 Pacesetter, Inc. Methods and systems for detecting the presence of T-wave alternans
US7738956B1 (en) 2006-01-27 2010-06-15 Pacesetter, Inc. Pacing schemes for revealing T-wave alternans (TWA) at low to moderate heart rates
US7599733B1 (en) 2006-02-14 2009-10-06 Pacesetter, Inc. Frequency domain monitoring of myocardial electrical stability
US7949390B1 (en) * 2006-02-14 2011-05-24 Pacesetter, Inc. Time domain monitoring of myocardial electrical stability
US7620448B1 (en) 2006-06-02 2009-11-17 Pacesetter, Inc. Methods and devices for monitoring myocardial mechanical stability
US20080015452A1 (en) * 2006-06-30 2008-01-17 Ricci Carlos A Method of processing electrocardiogram waveform
US8437837B2 (en) * 2006-09-29 2013-05-07 Medtronic, Inc. Method and apparatus for induced T-wave alternans assessment
US8126539B2 (en) 2007-10-12 2012-02-28 Medtronic, Inc. Method and apparatus for monitoring T-wave alternans
US8634903B2 (en) * 2009-10-30 2014-01-21 Medtronic, Inc. Measuring T-Wave alternans
US8620414B2 (en) 2010-03-30 2013-12-31 Medtronic, Inc. Detection of T-wave alternans phase reversal for arrhythmia prediction and sudden cardiac death risk stratification
US8886296B2 (en) 2011-10-14 2014-11-11 Medtronic, Inc. T-wave oversensing
US8521281B2 (en) 2011-10-14 2013-08-27 Medtronic, Inc. Electrogram classification algorithm
KR101197921B1 (en) * 2011-10-18 2012-11-05 삼성전기주식회사 Multi-layered ceramic electronic component
US10765876B2 (en) * 2018-04-27 2020-09-08 Medtronic, Inc. Method and apparatus for delivering anti-tachycardia pacing
US10772525B2 (en) 2018-06-05 2020-09-15 Medtronic, Inc. Cardiac signal t-wave detection
US11522919B2 (en) 2019-01-31 2022-12-06 Medtronic, Inc. Establishing a secure communication link

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Title
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Also Published As

Publication number Publication date
DE602004006228T2 (en) 2007-12-27
WO2004062486A2 (en) 2004-07-29
US20040186527A1 (en) 2004-09-23
CA2514876A1 (en) 2004-07-29
US20100145404A1 (en) 2010-06-10
DE602004006228D1 (en) 2007-06-14
US7725172B2 (en) 2010-05-25
EP1585443B1 (en) 2007-05-02
US8175695B2 (en) 2012-05-08
EP1585443A2 (en) 2005-10-19

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