WO2004066934A2 - Spermicidal and/or antifungal composition and methods of using the same - Google Patents
Spermicidal and/or antifungal composition and methods of using the same Download PDFInfo
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- WO2004066934A2 WO2004066934A2 PCT/US2004/000206 US2004000206W WO2004066934A2 WO 2004066934 A2 WO2004066934 A2 WO 2004066934A2 US 2004000206 W US2004000206 W US 2004000206W WO 2004066934 A2 WO2004066934 A2 WO 2004066934A2
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- Prior art keywords
- compound
- iso
- hydrogen
- propyl
- formula
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- 230000009933 reproductive health Effects 0.000 description 1
- 230000027272 reproductive process Effects 0.000 description 1
- 230000006965 reversible inhibition Effects 0.000 description 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
- 229960001860 salicylate Drugs 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 230000001932 seasonal effect Effects 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 229940125723 sedative agent Drugs 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 238000010956 selective crystallization Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 231100000872 sexual dysfunction Toxicity 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 238000002603 single-photon emission computed tomography Methods 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 230000000707 stereoselective effect Effects 0.000 description 1
- 230000010009 steroidogenesis Effects 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 229910052682 stishovite Inorganic materials 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 210000001578 tight junction Anatomy 0.000 description 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 231100000816 toxic dose Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 229910052905 tridymite Inorganic materials 0.000 description 1
- 238000001665 trituration Methods 0.000 description 1
- 230000002408 ulcerprotective effect Effects 0.000 description 1
- 210000003934 vacuole Anatomy 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
- 238000003260 vortexing Methods 0.000 description 1
- 238000004073 vulcanization Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Abstract
Description
Claims
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
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JP2006536504A JP4597136B2 (en) | 2003-01-24 | 2004-01-23 | Speritizing and / or bactericidal composition and method of use thereof |
DE602004031588T DE602004031588D1 (en) | 2003-01-24 | 2004-01-23 | COMPOSITION WITH SPERMICIDAL EFFECT AND METHOD FOR ITS APPLICATION |
CA002514047A CA2514047A1 (en) | 2003-01-24 | 2004-01-23 | Spermicidal and/or antifungal composition and methods of using the same |
EP04704789A EP1585732B1 (en) | 2003-01-24 | 2004-01-23 | Spermicidal composition and methods of using the same |
UAA200508141A UA82864C2 (en) | 2003-01-24 | 2004-01-23 | Spermicidal and/or antifungal composition and methods of using the same |
BR0406572-7A BRPI0406572A (en) | 2003-01-24 | 2004-01-23 | Spermicidal and / or antifungal composition and methods of employing same |
MXPA05007892A MXPA05007892A (en) | 2003-01-24 | 2004-01-23 | Spermicidal and/or antifungal composition and methods of using the same. |
AU2004207436A AU2004207436B2 (en) | 2003-01-24 | 2004-01-23 | Spermicidal and/or antifungal composition and methods of using the same |
AT04704789T ATE499914T1 (en) | 2003-01-24 | 2004-01-23 | COMPOSITION HAVING SPERMICIDAL EFFECT AND METHOD FOR USE THEREOF |
US10/895,959 US7294259B2 (en) | 2003-02-13 | 2004-07-22 | Membrane module for gas transfer |
IL169784A IL169784A0 (en) | 2003-01-24 | 2005-07-20 | Spermicidal and fungicidal compositions containing hexahydroindenopyridine derivatives and methods utilizing the same |
NO20053913A NO20053913L (en) | 2003-01-24 | 2005-08-22 | Spermicidal and / or antifungal composition and methods for using the same. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/350,232 US7544696B2 (en) | 2003-01-24 | 2003-01-24 | Spermicidal and/or antifungal composition and methods of using the same |
US10/350,232 | 2003-01-24 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
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US10/801,660 Continuation-In-Part US7169295B2 (en) | 2003-02-13 | 2004-03-17 | Supported biofilm apparatus and process |
Publications (2)
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WO2004066934A2 true WO2004066934A2 (en) | 2004-08-12 |
WO2004066934A3 WO2004066934A3 (en) | 2005-05-19 |
Family
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PCT/US2004/000206 WO2004066934A2 (en) | 2003-01-24 | 2004-01-23 | Spermicidal and/or antifungal composition and methods of using the same |
Country Status (20)
Country | Link |
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US (2) | US7544696B2 (en) |
EP (1) | EP1585732B1 (en) |
JP (2) | JP4597136B2 (en) |
KR (1) | KR20050103282A (en) |
CN (1) | CN1751027A (en) |
AT (1) | ATE499914T1 (en) |
AU (1) | AU2004207436B2 (en) |
BR (1) | BRPI0406572A (en) |
CA (1) | CA2514047A1 (en) |
CO (1) | CO5670353A2 (en) |
DE (1) | DE602004031588D1 (en) |
EC (1) | ECSP055992A (en) |
ES (1) | ES2359814T3 (en) |
IL (1) | IL169784A0 (en) |
MX (1) | MXPA05007892A (en) |
NO (1) | NO20053913L (en) |
RU (1) | RU2346687C2 (en) |
UA (1) | UA82864C2 (en) |
WO (1) | WO2004066934A2 (en) |
ZA (1) | ZA200505870B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009026375A2 (en) * | 2007-08-21 | 2009-02-26 | Lehigh University | Spermicidal and microbicidal compositions |
JP2009534416A (en) * | 2006-04-19 | 2009-09-24 | リサーチ・トライアングル・インスティチュート | Anti-spermatogenesis, spermicidal and / or anti-fungal compositions and methods of using said compositions |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7795436B2 (en) | 2005-08-24 | 2010-09-14 | Bristol-Myers Squibb Company | Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists |
Citations (12)
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US2470108A (en) | 1949-05-17 | Heterocyclic amines | ||
US2470109A (en) | 1949-05-17 | Heterocyclic amines | ||
US2546652A (en) | 1949-07-30 | 1951-03-27 | Hoffmann La Roche | Pyridindenes and process for their manufacture |
US3408353A (en) | 1964-01-17 | 1968-10-29 | Sandoz Ltd | 1, 3, 4, 9b-tetrahydro-2h-indeno(1, 2-c)pyridine derivatives |
US3462443A (en) | 1967-04-19 | 1969-08-19 | Mcneilab Inc | Indeno(1,2-c)pyridine derivatives |
US3497517A (en) | 1968-03-28 | 1970-02-24 | Sandoz Ag | 1,3,4,9b-tetrahydro-2h-indeno(1,2-c) pyridines |
US3574686A (en) | 1968-05-21 | 1971-04-13 | Sandoz Ltd | 2,5 - dimethyl - 1,3,4,9b - tetrahydro-2h-indeno(1,2-c)pyridine and salts thereof |
US3627773A (en) | 1969-06-09 | 1971-12-14 | Sandoz Ltd | 1,3,4,4A,5,9B-HEXAHYDRO-5-PHENYL-2H-INDENO{8 1,2-c{9 -PYRIDINES |
US3678058A (en) | 1969-05-07 | 1972-07-18 | Sandoz Ltd | 1,3,4,9B-TETRAHYDRO-2(2H)-INDENO-{8 1,2-c{9 PYRIDINES |
US3678057A (en) | 1970-03-26 | 1972-07-18 | Sandoz Ltd | 1,3,4,4A,5,9B-HEXAHYDRO-5-PHENYL-2H-INDENO{8 1,2-c{9 -PYRIDINES |
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US5314917A (en) | 1991-03-22 | 1994-05-24 | E. B. Michaels Research Associates, Inc. | Method for inactivating enveloped viruses and sperm |
US5952336A (en) | 1997-01-31 | 1999-09-14 | Research Triangle Institute | Hexahydroindenopyridine compounds having antispermatogenic activity |
-
2003
- 2003-01-24 US US10/350,232 patent/US7544696B2/en not_active Expired - Fee Related
-
2004
- 2004-01-23 CN CNA2004800047483A patent/CN1751027A/en active Pending
- 2004-01-23 AT AT04704789T patent/ATE499914T1/en not_active IP Right Cessation
- 2004-01-23 RU RU2005126720/14A patent/RU2346687C2/en not_active IP Right Cessation
- 2004-01-23 KR KR1020057013691A patent/KR20050103282A/en not_active Application Discontinuation
- 2004-01-23 JP JP2006536504A patent/JP4597136B2/en not_active Expired - Fee Related
- 2004-01-23 UA UAA200508141A patent/UA82864C2/en unknown
- 2004-01-23 WO PCT/US2004/000206 patent/WO2004066934A2/en active Application Filing
- 2004-01-23 MX MXPA05007892A patent/MXPA05007892A/en not_active Application Discontinuation
- 2004-01-23 EP EP04704789A patent/EP1585732B1/en not_active Expired - Lifetime
- 2004-01-23 ZA ZA200505870A patent/ZA200505870B/en unknown
- 2004-01-23 BR BR0406572-7A patent/BRPI0406572A/en not_active IP Right Cessation
- 2004-01-23 CA CA002514047A patent/CA2514047A1/en not_active Abandoned
- 2004-01-23 ES ES04704789T patent/ES2359814T3/en not_active Expired - Lifetime
- 2004-01-23 AU AU2004207436A patent/AU2004207436B2/en not_active Ceased
- 2004-01-23 DE DE602004031588T patent/DE602004031588D1/en not_active Expired - Lifetime
-
2005
- 2005-07-20 IL IL169784A patent/IL169784A0/en unknown
- 2005-08-22 NO NO20053913A patent/NO20053913L/en not_active Application Discontinuation
- 2005-08-22 CO CO05083226A patent/CO5670353A2/en not_active Application Discontinuation
- 2005-08-31 EC EC2005005992A patent/ECSP055992A/en unknown
-
2008
- 2008-11-25 US US12/277,708 patent/US8193213B2/en not_active Expired - Fee Related
-
2010
- 2010-06-22 JP JP2010141878A patent/JP2010202671A/en active Pending
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US2470108A (en) | 1949-05-17 | Heterocyclic amines | ||
US2470109A (en) | 1949-05-17 | Heterocyclic amines | ||
US2546652A (en) | 1949-07-30 | 1951-03-27 | Hoffmann La Roche | Pyridindenes and process for their manufacture |
US3408353A (en) | 1964-01-17 | 1968-10-29 | Sandoz Ltd | 1, 3, 4, 9b-tetrahydro-2h-indeno(1, 2-c)pyridine derivatives |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009534416A (en) * | 2006-04-19 | 2009-09-24 | リサーチ・トライアングル・インスティチュート | Anti-spermatogenesis, spermicidal and / or anti-fungal compositions and methods of using said compositions |
WO2009026375A2 (en) * | 2007-08-21 | 2009-02-26 | Lehigh University | Spermicidal and microbicidal compositions |
WO2009026375A3 (en) * | 2007-08-21 | 2009-04-23 | Univ Lehigh | Spermicidal and microbicidal compositions |
Also Published As
Publication number | Publication date |
---|---|
RU2346687C2 (en) | 2009-02-20 |
IL169784A0 (en) | 2007-07-04 |
US20090149490A1 (en) | 2009-06-11 |
EP1585732A4 (en) | 2009-01-28 |
AU2004207436B2 (en) | 2009-08-06 |
JP2010202671A (en) | 2010-09-16 |
ES2359814T3 (en) | 2011-05-27 |
WO2004066934A3 (en) | 2005-05-19 |
RU2005126720A (en) | 2006-02-10 |
CN1751027A (en) | 2006-03-22 |
NO20053913L (en) | 2005-08-22 |
ZA200505870B (en) | 2006-10-25 |
US8193213B2 (en) | 2012-06-05 |
JP2007506806A (en) | 2007-03-22 |
US7544696B2 (en) | 2009-06-09 |
EP1585732A2 (en) | 2005-10-19 |
KR20050103282A (en) | 2005-10-28 |
US20040147539A1 (en) | 2004-07-29 |
AU2004207436A1 (en) | 2004-08-12 |
CO5670353A2 (en) | 2006-08-31 |
BRPI0406572A (en) | 2005-12-20 |
EP1585732B1 (en) | 2011-03-02 |
JP4597136B2 (en) | 2010-12-15 |
DE602004031588D1 (en) | 2011-04-14 |
UA82864C2 (en) | 2008-05-26 |
MXPA05007892A (en) | 2005-11-17 |
ATE499914T1 (en) | 2011-03-15 |
CA2514047A1 (en) | 2004-08-12 |
ECSP055992A (en) | 2006-01-16 |
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