WO2004075746A3 - Method and system for analysing and processing ph0t0plethysmogram signals using wavelet transform - Google Patents

Method and system for analysing and processing ph0t0plethysmogram signals using wavelet transform Download PDF

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Publication number
WO2004075746A3
WO2004075746A3 PCT/GB2004/000808 GB2004000808W WO2004075746A3 WO 2004075746 A3 WO2004075746 A3 WO 2004075746A3 GB 2004000808 W GB2004000808 W GB 2004000808W WO 2004075746 A3 WO2004075746 A3 WO 2004075746A3
Authority
WO
WIPO (PCT)
Prior art keywords
signal
pulse oximetry
pulse
oximetry signal
feature extraction
Prior art date
Application number
PCT/GB2004/000808
Other languages
French (fr)
Other versions
WO2004075746A2 (en
Inventor
Paul Stanley Addison
James Nicholas Watson
Original Assignee
Cardiodigital Ltd
Paul Stanley Addison
James Nicholas Watson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0304413A external-priority patent/GB0304413D0/en
Priority claimed from GB0305168A external-priority patent/GB0305168D0/en
Priority claimed from GB0403066A external-priority patent/GB0403066D0/en
Priority to JP2006502334A priority Critical patent/JP4526532B2/en
Priority to AT04715386T priority patent/ATE521279T1/en
Priority to EP04715386A priority patent/EP1628571B1/en
Priority to US10/547,430 priority patent/US8255029B2/en
Application filed by Cardiodigital Ltd, Paul Stanley Addison, James Nicholas Watson filed Critical Cardiodigital Ltd
Publication of WO2004075746A2 publication Critical patent/WO2004075746A2/en
Publication of WO2004075746A3 publication Critical patent/WO2004075746A3/en
Priority to US13/590,103 priority patent/US20130046160A1/en
Priority to US13/590,105 priority patent/US9192336B2/en
Priority to US13/590,100 priority patent/US9220459B2/en
Priority to US13/590,095 priority patent/US9198616B2/en
Priority to US13/590,108 priority patent/US20130046161A1/en
Priority to US13/590,120 priority patent/US20130046186A1/en
Priority to US13/590,111 priority patent/US9220460B2/en
Priority to US13/590,112 priority patent/US20130046157A1/en
Priority to US13/590,102 priority patent/US20130046188A1/en
Priority to US14/749,481 priority patent/US10182764B2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7253—Details of waveform analysis characterised by using transforms
    • A61B5/726—Details of waveform analysis characterised by using transforms using Wavelet transforms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02416—Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/0816—Measuring devices for examining respiratory frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552—Details of sensors specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4806—Sleep evaluation
    • A61B5/4818—Sleep apnoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6825—Hand
    • A61B5/6826—Finger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6829—Foot or ankle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6838—Clamps or clips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6887—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient mounted on external non-worn devices, e.g. non-medical devices
    • A61B5/6896—Toys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • A61B5/7214—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts using signal cancellation, e.g. based on input of two identical physiological sensors spaced apart, or based on two signals derived from the same sensor, for different optical wavelengths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7278—Artificial waveform generation or derivation, e.g. synthesising signals from measured signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7282—Event detection, e.g. detecting unique waveforms indicative of a medical condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient ; user input means
    • A61B5/742—Details of notification to user or communication with user or patient ; user input means using visual displays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G01N21/3151—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths using two sources of radiation of different wavelengths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00—Evaluating a particular growth phase or type of persons or animals
    • A61B2503/06—Children, e.g. for attention deficit diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02438—Detecting, measuring or recording pulse rate or heart rate with portable devices, e.g. worn by the patient

Abstract

A physiological measurement system is disclosed which can take a pulse oximetry signal such as a photoplethysmo-gram from a patient and then analyse the signal to measure physiological parameters including respiration, pulse, oxygen saturation and movement. The system can be used as a general monitor, or more specifically, to for infant or adult apnea, and to guard against sudden infant death syndrome. The system comprises a pulse oximeter which includes a light emitting device and a photodetector attachable to a subject to obtain a pulse oximetry signal; analogue to digital converter means arranged to convert said pulse oximetry signal into a digital pulse oximetry signal; signal processing means suitable to receive said digital pulse oximetry signal and arranged to decompose that signal by wavelet transform means; feature extraction means arranged to derive physiological information from the decomposed signal; an analyser component arranged to collect information from the feature extraction means; and data output means arranged in communication with the analyser component.
PCT/GB2004/000808 2003-02-27 2004-02-27 Method and system for analysing and processing ph0t0plethysmogram signals using wavelet transform WO2004075746A2 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
JP2006502334A JP4526532B2 (en) 2003-02-27 2004-02-27 Signal analysis and processing methods
AT04715386T ATE521279T1 (en) 2003-02-27 2004-02-27 METHOD AND DEVICE FOR EVALUATION AND PROCESSING PHOTOPLETHYSMOGRAPHIC SIGNALS BY WAVE TRANSFORMATION ANALYSIS
EP04715386A EP1628571B1 (en) 2003-02-27 2004-02-27 Method and system for analysing and processing photoplethysmogram signals using wavelet transform analysis
US10/547,430 US8255029B2 (en) 2003-02-27 2004-02-27 Method of analyzing and processing signals
US13/590,103 US20130046160A1 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,102 US20130046188A1 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,112 US20130046157A1 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,111 US9220460B2 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,120 US20130046186A1 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,108 US20130046161A1 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,105 US9192336B2 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,100 US9220459B2 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,095 US9198616B2 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US14/749,481 US10182764B2 (en) 2003-02-27 2015-06-24 Method of analyzing and processing signals

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB0304413.8 2003-02-27
GB0304413A GB0304413D0 (en) 2003-02-27 2003-02-27 Method and apparatus of analysing and processing pulse oximetry signals
GB0305168.7 2003-03-07
GB0305168A GB0305168D0 (en) 2003-03-07 2003-03-07 Method of analysing and processing signals
GB0403066.4 2004-02-12
GB0403066A GB0403066D0 (en) 2004-02-12 2004-02-12 Method of analysing and processing signals

Related Child Applications (10)

Application Number Title Priority Date Filing Date
US10/547,430 A-371-Of-International US8255029B2 (en) 2003-02-27 2004-02-27 Method of analyzing and processing signals
US13/590,100 Continuation US9220459B2 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,105 Continuation US9192336B2 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,108 Continuation US20130046161A1 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,095 Continuation US9198616B2 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,112 Continuation US20130046157A1 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,103 Continuation US20130046160A1 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,111 Continuation US9220460B2 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,120 Continuation US20130046186A1 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals
US13/590,102 Continuation US20130046188A1 (en) 2003-02-27 2012-08-20 Method of analyzing and processing signals

Publications (2)

Publication Number Publication Date
WO2004075746A2 WO2004075746A2 (en) 2004-09-10
WO2004075746A3 true WO2004075746A3 (en) 2007-02-08

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2004/000808 WO2004075746A2 (en) 2003-02-27 2004-02-27 Method and system for analysing and processing ph0t0plethysmogram signals using wavelet transform

Country Status (5)

Country Link
US (11) US8255029B2 (en)
EP (2) EP1628571B1 (en)
JP (1) JP4526532B2 (en)
AT (1) ATE521279T1 (en)
WO (1) WO2004075746A2 (en)

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US9113815B2 (en) 2008-06-30 2015-08-25 Nellcor Puritan Bennett Ireland Systems and methods for ridge selection in scalograms of signals
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US9192336B2 (en) 2003-02-27 2015-11-24 Nellcor Puritan Bennett Ireland Method of analyzing and processing signals
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US8380271B2 (en) 2006-06-15 2013-02-19 Covidien Lp System and method for generating customizable audible beep tones and alarms
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US8219170B2 (en) 2006-09-20 2012-07-10 Nellcor Puritan Bennett Llc System and method for practicing spectrophotometry using light emitting nanostructure devices
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US7890153B2 (en) 2006-09-28 2011-02-15 Nellcor Puritan Bennett Llc System and method for mitigating interference in pulse oximetry
US7476131B2 (en) 2006-09-29 2009-01-13 Nellcor Puritan Bennett Llc Device for reducing crosstalk
US8068890B2 (en) 2006-09-29 2011-11-29 Nellcor Puritan Bennett Llc Pulse oximetry sensor switchover
US8175667B2 (en) 2006-09-29 2012-05-08 Nellcor Puritan Bennett Llc Symmetric LED array for pulse oximetry
US7680522B2 (en) 2006-09-29 2010-03-16 Nellcor Puritan Bennett Llc Method and apparatus for detecting misapplied sensors
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