WO2004082484A1 - Device for bone marrow biopsy - Google Patents

Device for bone marrow biopsy Download PDF

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Publication number
WO2004082484A1
WO2004082484A1 PCT/EP2004/002555 EP2004002555W WO2004082484A1 WO 2004082484 A1 WO2004082484 A1 WO 2004082484A1 EP 2004002555 W EP2004002555 W EP 2004002555W WO 2004082484 A1 WO2004082484 A1 WO 2004082484A1
Authority
WO
WIPO (PCT)
Prior art keywords
hollow needle
cutting edge
bush
bone
penetration
Prior art date
Application number
PCT/EP2004/002555
Other languages
French (fr)
Inventor
Carlo Bianchini
Original Assignee
Carlo Bianchini
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlo Bianchini filed Critical Carlo Bianchini
Publication of WO2004082484A1 publication Critical patent/WO2004082484A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0233—Pointed or sharp biopsy instruments
    • A61B10/025—Pointed or sharp biopsy instruments for taking bone, bone marrow or cartilage samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/16—Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
    • A61B17/1637—Hollow drills or saws producing a curved cut, e.g. cylindrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3472—Trocars; Puncturing needles for bones, e.g. intraosseus injections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0233—Pointed or sharp biopsy instruments
    • A61B10/025—Pointed or sharp biopsy instruments for taking bone, bone marrow or cartilage samples
    • A61B2010/0258—Marrow samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3403—Needle locating or guiding means
    • A61B2017/3405—Needle locating or guiding means using mechanical guide means

Definitions

  • the present invention relates to a device for bone marrow biopsy.
  • a device in order to perform bone marrow biopsy or aspiration, a device is currently known which is substantially constituted by a cylindrical tubular element or hollow needle, provided at one end with a grip element and at the other end with a cutting region that has an inclined cutting edge to be inserted in the bone from which the sample is to be taken by applying considerable manual force in order to achieve penetration; such penetration is rendered even more difficult by the fact that the tubular element above the cutting edge necessarily has a thickness and accordingly has an increase in diameter.
  • Another problem is further constituted by the fact that the pressure must be applied manually by the physician, who has no reference for evaluating the correct extent of the insertion of the needle or tubular element and therefore lacks a correct perception of the quantity of material that is sampled.
  • Another difficulty further arises from the fact that it is relatively difficult to insert the needle without causing inclinations, so that the core of removed material is frequently subject to fragmentation, with consequent difficulty in correct sampling.
  • the aim of the invention is to solve the problem noted above by providing a device for bone marrow biopsy that allows to insert the sampling needle without having to apply pressure manually and also allows very easy insertion.
  • Another object of the present invention is to provide a device that thanks to its particular constructive characteristics allows to perform sampling in an extremely short time.
  • a device for bone marrow biopsy characterized in that it comprises a guiding bush that can be coupled at one of its ends to the bone from which the sample is to be taken, said bush being able to slidingly accommodate a hollow needle that has a cutting edge for penetration at one end and, at the other end that protrudes from said bush, a shank for connection to motor means for turning said hollow needle.
  • Figure 1 is a schematic perspective view of the guiding bush before it is positioned on the bone;
  • Figure 2 is a perspective view of the guiding bush arranged in the sampling point and of the hollow needle to be inserted;
  • Figure 3 is a perspective view of the step for the insertion of the hollow needle
  • Figure 4 is a perspective view of the step of controlled penetration of the hollow needle
  • Figure 5 is a perspective view of the needle extraction step
  • Figure 6 is an enlarged-scale sectional view of the device arranged in position at the moment of needle insertion
  • Figure 7 is a view of the step of full insertion of the hollow sampling needle
  • Figure 8 is a view of the motor means connected to the hollow needle
  • Figure 9 is a view of the guiding bush with means for adjusting the extent of the penetration of the hollow needle
  • Figure 10 is a view of a particular embodiment of the cutting edge of the hollow needle
  • Figure 11 is an enlarged-scale sectional view of a detail of the cutting edge with the chamber for accommodating the sampled bone core. Ways of carrying out the Invention
  • the device for bone marrow biopsy comprises a guiding bush, which is generally designated by the reference numeral 1 and is constituted by a cylindrical body 2, which has at one of its axial ends spikes 3 for positioning in the correct point of the bone, generally designated by the reference numeral 4, where the sample is to be taken.
  • the cylindrical body advantageously has a cutting edgelike shape on the part where the spikes are provided; such shape facilitates penetration in the flesh during the initial step, and the cutting edge can also be obtained with a very limited thickness.
  • a ring 5 is provided that acts as a grip element for retaining and positioning the guiding bush.
  • the guiding bush forms an axial cavity 6 in which a hollow sampling needle can slide, such needle being generally designated by the reference numeral 10 and having, at one of its ends, a cutting edge 11 that is preferably of the sawtooth type.
  • the hollow needle 10 is provided with a shank 12 that can be connected to motor means, generally designated by the reference numeral 13, which are constituted for example by a battery-powered motor that turns the needle 10 at the speed deemed appropriate.
  • the outer surface of the needle 10 on the side provided with the cutting edge 11, there is a recess 15 that allows to form between the needle 10 and the axial cavity 6 an interspace in which it is possible to accommodate the material removed by the cutting edge 11 during its rotation.
  • the cutting edge 11 provides, as shown in Figure 11, a reduction in diameter at the cutting edge that corresponds to an increase in the diameter of the cavit 6 that accommodates the sampled material, which by expanding within the cavity 6 facilitates separation for sampling.
  • the cutting edge has any of a sawtooth shape, and for example, as shown in Figure 10, it is possible to provide a cutting edge
  • the shank 12 has an abutment edge 12a that engages the ring 5 and in practice determines the length of the penetration of the needle within the bone marrow, depending on the length of the core of material that is to be sampled.
  • the internal surface of the hollow needle can have rough regions, constituted for example by flutings, which facilitate removal of the produced core.
  • the needle is then inserted and penetrates by the action of motor means which, by turning the needle, cause the needle to penetrate without any effort the bone tissue and collect a core of material that can be removed by using a push rod which is inserted from the side of the shank 12.
  • An important aspect is further constituted by the fact that the bush, in addition to acting as a positioning element, correctly guides the descent of the needle and further provides a stop element, so that the extent of the penetration is always precisely controlled.
  • the materials used, as well as the contingent shapes and dimensions may be any according to requirements.

Abstract

A device for bone marrow biopsy comprising a guiding bush (1) that can be coupled at one of its ends to the bone from which the sample is to be taken; the bush can slidingly accommodate a hollow needle (10) that has a cutting edge (11) for penetration at one end and, at the other end that protrudes from the bush, a shank (12) for connection to motor means for turning the hollow needle.

Description

DEVICE FOR BONE MARROW BIOPSY
Technical Field
The present invention relates to a device for bone marrow biopsy.
Background Art As is known, in order to perform bone marrow biopsy or aspiration, a device is currently known which is substantially constituted by a cylindrical tubular element or hollow needle, provided at one end with a grip element and at the other end with a cutting region that has an inclined cutting edge to be inserted in the bone from which the sample is to be taken by applying considerable manual force in order to achieve penetration; such penetration is rendered even more difficult by the fact that the tubular element above the cutting edge necessarily has a thickness and accordingly has an increase in diameter.
Another problem is further constituted by the fact that the pressure must be applied manually by the physician, who has no reference for evaluating the correct extent of the insertion of the needle or tubular element and therefore lacks a correct perception of the quantity of material that is sampled.
Another difficulty further arises from the fact that it is relatively difficult to insert the needle without causing inclinations, so that the core of removed material is frequently subject to fragmentation, with consequent difficulty in correct sampling.
Disclosure of the Invention
The aim of the invention is to solve the problem noted above by providing a device for bone marrow biopsy that allows to insert the sampling needle without having to apply pressure manually and also allows very easy insertion.
Within this aim, an object of the invention is to provide a device of the disposable type that allows to adjust at will the extent of insertion and consequently the amount of material that is sampled. Another object of the present invention is to provide a device in which it is possible to perform precise positioning on the bone in the point where the sample is to be taken, without running the risk of jamming or undue movements of the sampling needle. Another object of the present invention is to provide a device that thanks to its particular constructive characteristics is capable of giving the greatest assurances of reliability and safety in use and allows to reduce significantly the time required for sampling.
Another object of the present invention is to provide a device that thanks to its particular constructive characteristics allows to perform sampling in an extremely short time.
This aim and these and other objects that will become better apparent hereinafter are achieved by a device for bone marrow biopsy according to the invention, characterized in that it comprises a guiding bush that can be coupled at one of its ends to the bone from which the sample is to be taken, said bush being able to slidingly accommodate a hollow needle that has a cutting edge for penetration at one end and, at the other end that protrudes from said bush, a shank for connection to motor means for turning said hollow needle. Brief Description of the Drawings
Further characteristics and advantages of the present invention will become better apparent f om the description of a preferred but not exclusive embodiment of a device for bone marrow biopsy, illustrated by way of non- limiting example in the accompanying drawings, wherein: Figure 1 is a schematic perspective view of the guiding bush before it is positioned on the bone;
Figure 2 is a perspective view of the guiding bush arranged in the sampling point and of the hollow needle to be inserted;
Figure 3 is a perspective view of the step for the insertion of the hollow needle; Figure 4 is a perspective view of the step of controlled penetration of the hollow needle;
Figure 5 is a perspective view of the needle extraction step;
Figure 6 is an enlarged-scale sectional view of the device arranged in position at the moment of needle insertion;
Figure 7 is a view of the step of full insertion of the hollow sampling needle;
Figure 8 is a view of the motor means connected to the hollow needle;
Figure 9 is a view of the guiding bush with means for adjusting the extent of the penetration of the hollow needle;
Figure 10 is a view of a particular embodiment of the cutting edge of the hollow needle;
Figure 11 is an enlarged-scale sectional view of a detail of the cutting edge with the chamber for accommodating the sampled bone core. Ways of carrying out the Invention
With reference to the figures, the device for bone marrow biopsy according to the invention comprises a guiding bush, which is generally designated by the reference numeral 1 and is constituted by a cylindrical body 2, which has at one of its axial ends spikes 3 for positioning in the correct point of the bone, generally designated by the reference numeral 4, where the sample is to be taken.
Furthermore, the cylindrical body advantageously has a cutting edgelike shape on the part where the spikes are provided; such shape facilitates penetration in the flesh during the initial step, and the cutting edge can also be obtained with a very limited thickness.
At the other end of the cylindrical body 2 a ring 5 is provided that acts as a grip element for retaining and positioning the guiding bush.
The guiding bush forms an axial cavity 6 in which a hollow sampling needle can slide, such needle being generally designated by the reference numeral 10 and having, at one of its ends, a cutting edge 11 that is preferably of the sawtooth type.
It is also possible to provide a pin that initially allows to penetrate the flesh until the bone is reached, after which the pin is removed.
At the other end, the hollow needle 10 is provided with a shank 12 that can be connected to motor means, generally designated by the reference numeral 13, which are constituted for example by a battery-powered motor that turns the needle 10 at the speed deemed appropriate.
Advantageously, on the outer surface of the needle 10, on the side provided with the cutting edge 11, there is a recess 15 that allows to form between the needle 10 and the axial cavity 6 an interspace in which it is possible to accommodate the material removed by the cutting edge 11 during its rotation.
Moreovers the cutting edge 11 provides, as shown in Figure 11, a reduction in diameter at the cutting edge that corresponds to an increase in the diameter of the cavit 6 that accommodates the sampled material, which by expanding within the cavity 6 facilitates separation for sampling.
Advantageously, the cutting edge has any of a sawtooth shape, and for example, as shown in Figure 10, it is possible to provide a cutting edge
11 that is formed by means of teeth 20 for removing material, at the base of which there is a recess 21 that facilitates the accumulation of the removed material.
It should be added to the above that the cutting edge 11 is inclined outwardly in order to facilitate centering.
With the arrangement described above, the shank 12 has an abutment edge 12a that engages the ring 5 and in practice determines the length of the penetration of the needle within the bone marrow, depending on the length of the core of material that is to be sampled.
Advantageously, the internal surface of the hollow needle can have rough regions, constituted for example by flutings, which facilitate removal of the produced core. As shown in Figure 9, it is also possible to adjust the penetration length and accordingly the amount of removed material by providing an adjustable ring 30 that can be arranged on the cylindrical body 2 by virtue of the presence of a male threaded portion 31 on the body 2 and of a female threaded seat 32 provided on the ring.
With the arrangement described above, it is therefore possible to perform bone marrow biopsy very rapidly and in a low-traumatic manner, since the physician does not have to apply a violent force but instead merely has to correctly position the bush by inserting it up to the bone, in practice cutting a cylinder of flesh, which is preferably removed by removing beforehand the bush and extracting the cylinder of flesh, subsequently repositioning the bush in the tissue.
The needle is then inserted and penetrates by the action of motor means which, by turning the needle, cause the needle to penetrate without any effort the bone tissue and collect a core of material that can be removed by using a push rod which is inserted from the side of the shank 12.
An important aspect is further constituted by the fact that the bush, in addition to acting as a positioning element, correctly guides the descent of the needle and further provides a stop element, so that the extent of the penetration is always precisely controlled.
The invention thus conceived is susceptible of numerous modifications and variations, all of which are within the scope of the appended claims.
All the details may further be replaced with other technically equivalent elements.
In practice, the materials used, as well as the contingent shapes and dimensions, may be any according to requirements.
The disclosures in Italian Patent Application No. MI2003A000522 from which this application claims priority are incorporated herein by reference.

Claims

1. A device for bone marrow biopsy, characterized in that it comprises a guiding bush that can be coupled at one of its ends to the bone from which the sample is to be taken, said bush being able to slidingly accommodate a hollow needle that has a cutting edge for penetration at one end and, at another end that protrudes from said bush, a shank for connection to motor means for turning said hollow needle.
2. The device according to claim 1, characterized in that said guiding bush has positioning means at the end that is directed toward the bone.
3. The device according to claim 1, characterized in that said bush has a cutting edge at an end directed toward the bone in order to facilitate penetration in the flesh.
4. The device according to claim 2, characterized in that said positioning means are constituted by spikes that protrude from an axial end of said bush.
5. The device according to claim 4, characterized in that said bush has a cylindrical body that forms said spikes or said cutting edge at one end and forms at another end a ring that is adapted to act as a grip element.
6. The device according to claim 5, characterized in that said cylindrical body forms an axial cavity for slidingly accommodating said hollow needle.
7. The device according to claim 1, characterized in that said motor means are constituted by a battery-powered motor for turning said hollow needle.
8. The device according to claim 1, characterized in that said motor means can be operated manually.
9. The device according to claim 1, characterized in that said hollow needle is externally provided with a recess from the end toward said cutting edge.
10. The device according to claim 1, characterized in that it comprises, on the inner surface of said hollow needle, rough portions that are adapted to facilitate removal of the resulting core of material.
11. The device according to claim 1, characterized in that said cutting edge protrudes outwardly in order to facilitate centering.
12. The device according to claim 6, characterized in that said cutting edge protrudes inwardly in order to increase the diameter of the axial cavity formed by said hollow needle.
13. The device according to claim 1, characterized in that said cutting edge is sawtooth-shaped.
14. The device according to claim 1, characterized in that said cutting edge has removal teeth at the base of which there is a recess.
15. The device according to claim 5, characterized in that said shank forms an abutment edge that engages said ring in order to determine the length of the penetration of said hollow needle.
16. The device according to claim 5, characterized in that it comprises, on said cylindrical body of said guiding bush, an adjustable ring for presetting the penetration length of said hollow needle.
PCT/EP2004/002555 2003-03-18 2004-03-11 Device for bone marrow biopsy WO2004082484A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI20030522 ITMI20030522A1 (en) 2003-03-18 2003-03-18 DEVICE FOR BONE MARROW BIOPSY
ITMI2003A000522 2003-03-18

Publications (1)

Publication Number Publication Date
WO2004082484A1 true WO2004082484A1 (en) 2004-09-30

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IT (1) ITMI20030522A1 (en)
WO (1) WO2004082484A1 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006138018A2 (en) * 2005-06-14 2006-12-28 University Of Florida Research Foundation, Inc. Multi-purpose dental mirrors and related dental instruments
WO2007093192A1 (en) * 2006-02-16 2007-08-23 Universite Libre De Bruxelles Surgical boring tool set
WO2011135070A3 (en) * 2010-04-29 2011-12-29 Mario Wieser Bone biopsy cutter
EP2543321A1 (en) * 2011-07-05 2013-01-09 Johan Janssens Combination of a bone drill and a sleeve
US9402602B2 (en) 2013-01-25 2016-08-02 Choon Kee Lee Tissue sampling apparatus
US9925068B2 (en) 2014-05-30 2018-03-27 Treace Medical Concepts, Inc. Bone harvester and bone marrow removal system and method
KR101870921B1 (en) * 2016-11-24 2018-06-25 서울대학교산학협력단 Probe of aspirating biological tissue, and apparatus of aspirating biological tissue having the same
WO2019245611A1 (en) * 2018-06-22 2019-12-26 In2Bones Usa, Llc Bone graft harvester

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4142517A (en) * 1976-07-23 1979-03-06 Contreras Guerrero De Stavropo Apparatus for extracting bone marrow specimens
GB2100151A (en) * 1981-05-13 1982-12-22 Jancy Eng Annular hole cutter
US4798213A (en) * 1987-09-09 1989-01-17 Doppelt Samuel H Bone biopsy apparatus
EP0574736A1 (en) * 1992-06-06 1993-12-22 MERCK PATENT GmbH Drilling and abrasion tool for bony materials
WO1997016118A1 (en) * 1995-10-30 1997-05-09 Biomedical Enterprises, Inc. Materials collection system and uses thereof
US6110128A (en) * 1998-12-11 2000-08-29 Andelin; John B. Bone marrow biopsy needle and method for using the same
EP1175870A1 (en) * 2000-07-26 2002-01-30 Sulzer Orthopedics Ltd. Hollow drills for obtaining bone material

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4142517A (en) * 1976-07-23 1979-03-06 Contreras Guerrero De Stavropo Apparatus for extracting bone marrow specimens
GB2100151A (en) * 1981-05-13 1982-12-22 Jancy Eng Annular hole cutter
US4798213A (en) * 1987-09-09 1989-01-17 Doppelt Samuel H Bone biopsy apparatus
EP0574736A1 (en) * 1992-06-06 1993-12-22 MERCK PATENT GmbH Drilling and abrasion tool for bony materials
WO1997016118A1 (en) * 1995-10-30 1997-05-09 Biomedical Enterprises, Inc. Materials collection system and uses thereof
US6110128A (en) * 1998-12-11 2000-08-29 Andelin; John B. Bone marrow biopsy needle and method for using the same
EP1175870A1 (en) * 2000-07-26 2002-01-30 Sulzer Orthopedics Ltd. Hollow drills for obtaining bone material

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006138018A2 (en) * 2005-06-14 2006-12-28 University Of Florida Research Foundation, Inc. Multi-purpose dental mirrors and related dental instruments
WO2006138018A3 (en) * 2005-06-14 2007-04-12 Univ Florida Multi-purpose dental mirrors and related dental instruments
WO2007093192A1 (en) * 2006-02-16 2007-08-23 Universite Libre De Bruxelles Surgical boring tool set
US20090228012A1 (en) * 2006-02-16 2009-09-10 Universite Libre De Bruxelles Surgical boring tool set
WO2011135070A3 (en) * 2010-04-29 2011-12-29 Mario Wieser Bone biopsy cutter
EP2543321A1 (en) * 2011-07-05 2013-01-09 Johan Janssens Combination of a bone drill and a sleeve
US9402602B2 (en) 2013-01-25 2016-08-02 Choon Kee Lee Tissue sampling apparatus
US9925068B2 (en) 2014-05-30 2018-03-27 Treace Medical Concepts, Inc. Bone harvester and bone marrow removal system and method
US11020244B2 (en) 2014-05-30 2021-06-01 Treace Medical Concepts, Inc. Bone harvester and bone marrow removal system and method
KR101870921B1 (en) * 2016-11-24 2018-06-25 서울대학교산학협력단 Probe of aspirating biological tissue, and apparatus of aspirating biological tissue having the same
WO2019245611A1 (en) * 2018-06-22 2019-12-26 In2Bones Usa, Llc Bone graft harvester

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