WO2004091542A3 - Nitrogen containing integrin targeting compounds - Google Patents

Nitrogen containing integrin targeting compounds Download PDF

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Publication number
WO2004091542A3
WO2004091542A3 PCT/US2004/012034 US2004012034W WO2004091542A3 WO 2004091542 A3 WO2004091542 A3 WO 2004091542A3 US 2004012034 W US2004012034 W US 2004012034W WO 2004091542 A3 WO2004091542 A3 WO 2004091542A3
Authority
WO
WIPO (PCT)
Prior art keywords
integrin targeting
nitrogen containing
targeting compounds
containing integrin
compounds
Prior art date
Application number
PCT/US2004/012034
Other languages
French (fr)
Other versions
WO2004091542A2 (en
Inventor
Amir Tamiz
Curt W Bradshaw
Original Assignee
Covx Pharmaceuticals Inc
Amir Tamiz
Curt W Bradshaw
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Covx Pharmaceuticals Inc, Amir Tamiz, Curt W Bradshaw filed Critical Covx Pharmaceuticals Inc
Publication of WO2004091542A2 publication Critical patent/WO2004091542A2/en
Publication of WO2004091542A3 publication Critical patent/WO2004091542A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention provides integrin targeting compounds which comprise small molecular weight integrin targeting agent-linker conjugates which are linked to a polymer such as a protein. Various uses of the invention compounds are provided, including methods to prevent or treat cancer or other disease.
PCT/US2004/012034 2003-04-15 2004-04-15 Nitrogen containing integrin targeting compounds WO2004091542A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US46345603P 2003-04-15 2003-04-15
US60/463,456 2003-04-15
US50788703P 2003-09-30 2003-09-30
US60/507,887 2003-09-30

Publications (2)

Publication Number Publication Date
WO2004091542A2 WO2004091542A2 (en) 2004-10-28
WO2004091542A3 true WO2004091542A3 (en) 2005-04-14

Family

ID=33303121

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/012034 WO2004091542A2 (en) 2003-04-15 2004-04-15 Nitrogen containing integrin targeting compounds

Country Status (1)

Country Link
WO (1) WO2004091542A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1853294A4 (en) * 2005-03-03 2010-01-27 Covx Technologies Ireland Ltd Anti-angiogenic compounds
US7501404B2 (en) * 2005-04-04 2009-03-10 Daimed Substituted azetidinones
WO2007015168A2 (en) 2005-07-01 2007-02-08 Dako Denmark A/S Monomeric and polymeric linkers useful for conjugating biological molecules and other substances
EP2606911A1 (en) * 2007-02-16 2013-06-26 KTB Tumorforschungsgesellschaft mbH Receptor And Antigen Targeted Prodrug
SI2019104T1 (en) 2007-07-19 2013-12-31 Sanofi Cytotoxic agents comprising new tomaymycin derivatives and their therapeutic use
WO2010093706A2 (en) * 2009-02-10 2010-08-19 The Scripps Research Institute Chemically programmed vaccination
CN106565825A (en) * 2015-10-12 2017-04-19 复旦大学 Stabilized A7R polypeptide and application of polypeptide in construction of tumor targeted diagnosis and treatment drug delivery system

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048861A (en) * 1997-12-17 2000-04-11 Merck & Co., Inc. Integrin receptor antagonists

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048861A (en) * 1997-12-17 2000-04-11 Merck & Co., Inc. Integrin receptor antagonists

Also Published As

Publication number Publication date
WO2004091542A2 (en) 2004-10-28

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