WO2004099433A3 - Electrochemical method to measure dna attachment to an electrode surface in the presence of molecular oxygen - Google Patents
Electrochemical method to measure dna attachment to an electrode surface in the presence of molecular oxygen Download PDFInfo
- Publication number
- WO2004099433A3 WO2004099433A3 PCT/US2004/013514 US2004013514W WO2004099433A3 WO 2004099433 A3 WO2004099433 A3 WO 2004099433A3 US 2004013514 W US2004013514 W US 2004013514W WO 2004099433 A3 WO2004099433 A3 WO 2004099433A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- molecular oxygen
- ruthenium
- electrode surface
- electrochemical method
- nucleic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002524263A CA2524263A1 (en) | 2003-05-02 | 2004-04-30 | Electrochemical method to measure dna attachment to an electrode surface in the presence of molecular oxygen |
DE602004029152T DE602004029152D1 (en) | 2003-05-02 | 2004-04-30 | ELECTROCHEMICAL METHOD FOR MEASURING BINDING OF DNA TO AN ELECTRODE SURFACE IN THE PRESENCE OF MOLECULAR OXYGEN |
EP04751075A EP1620570B1 (en) | 2003-05-02 | 2004-04-30 | Electrochemical method to measure dna attachment to an electrode surface in the presence of molecular oxygen |
AU2004236714A AU2004236714B2 (en) | 2003-05-02 | 2004-04-30 | Electrochemical method to measure DNA attachment to an electrode surface in the presence of molecular oxygen |
JP2006514196A JP4666525B2 (en) | 2003-05-02 | 2004-04-30 | Electrochemical method for measuring DNA binding to electrode surfaces in the presence of molecular oxygen |
AT04751075T ATE481502T1 (en) | 2003-05-02 | 2004-04-30 | ELECTROCHEMICAL METHOD FOR MEASURING THE BINDING OF DNA TO AN ELECTRODE SURFACE IN THE PRESENCE OF MOLECULAR OXYGEN |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42465602P | 2002-11-06 | 2002-11-06 | |
US10/429,291 US7258978B2 (en) | 2002-11-06 | 2003-05-02 | Electrochemical method to measure DNA attachment to an electrode surface in the presence of molecular oxygen |
US10/429,291 | 2003-05-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004099433A2 WO2004099433A2 (en) | 2004-11-18 |
WO2004099433A3 true WO2004099433A3 (en) | 2005-07-21 |
Family
ID=32180020
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/013514 WO2004099433A2 (en) | 2002-11-06 | 2004-04-30 | Electrochemical method to measure dna attachment to an electrode surface in the presence of molecular oxygen |
Country Status (2)
Country | Link |
---|---|
US (3) | US7258978B2 (en) |
WO (1) | WO2004099433A2 (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7258978B2 (en) | 2002-11-06 | 2007-08-21 | Geneohm Sciences | Electrochemical method to measure DNA attachment to an electrode surface in the presence of molecular oxygen |
US20040086895A1 (en) * | 2002-11-06 | 2004-05-06 | Crothers Donald M. | Method of electrochemical detection of somatic cell mutations |
ATE456678T1 (en) * | 2003-11-10 | 2010-02-15 | Geneohm Sciences Inc | NUCLEIC ACID DETECTION METHOD WITH INCREASED SENSITIVITY |
WO2005059181A1 (en) | 2003-12-15 | 2005-06-30 | Geneohm Sciences, Inc. | Carbon electrode surface for attachment of dna and protein molecules |
US7341834B2 (en) * | 2003-12-15 | 2008-03-11 | Geneohn Sciences, Inc. | Multiplexed electrochemical detection system and method |
WO2006065598A2 (en) * | 2004-12-13 | 2006-06-22 | Geneohm Sciences, Inc. | Fluidic cartridges for electrochemical detection of dna |
US7820389B2 (en) * | 2007-01-10 | 2010-10-26 | Geneohm Sciences, Inc. | Inhibition of mismatch hybridization by a universal competitor DNA |
ES2310125B1 (en) * | 2007-05-25 | 2010-01-07 | Universidad Autonoma De Madrid | METHOD FOR THE ELECTROCHEMICAL DETECTION OF NUCLEIC ACID SEQUENCES. |
EP3279651B1 (en) | 2008-09-02 | 2019-06-12 | The Governing Council Of The University Of Toronto | Methods using microelectrodes and biosensing devices incorporating the same |
EP2663857B1 (en) | 2011-01-11 | 2018-12-12 | The Governing Council Of The University Of Toronto | Protein detection method |
US9828599B2 (en) | 2013-09-18 | 2017-11-28 | General Electric Company | Methods of selecting binding-elements and uses thereof |
US10359419B2 (en) | 2013-10-02 | 2019-07-23 | General Electric Company | Methods for detection of target using affinity binding |
CN105646459A (en) * | 2014-11-13 | 2016-06-08 | 上海和辉光电有限公司 | Compound and preparation method and application thereof |
US10465244B2 (en) * | 2014-12-17 | 2019-11-05 | Universiti Brunei Darussalam | Electrochemical DNA biosensor using graphene biochip for species identification |
GB201507452D0 (en) * | 2015-04-30 | 2015-06-17 | Inside Biometrics Ltd | Electron transfer agent |
JP6346242B2 (en) | 2016-11-04 | 2018-06-20 | 株式会社東芝 | Nucleic acid detection method and assay kit |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4469863A (en) * | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
EP0149339B1 (en) * | 1983-12-16 | 1989-08-23 | MediSense, Inc. | Assay for nucleic acids |
US6316607B1 (en) * | 1986-04-30 | 2001-11-13 | Igen International, Inc. | Electrochemiluminescent assays |
US6207369B1 (en) * | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
US6180346B1 (en) * | 1995-06-27 | 2001-01-30 | The Universtiy Of North Carolina At Chapel Hill | Electropolymerizable film, and method of making and use thereof |
US6458322B1 (en) | 2000-09-08 | 2002-10-01 | Bioavailability Systems, Llc | Method for simplified shipping of clinical specimens and optional direct analysis |
JP2006170615A (en) * | 2001-01-19 | 2006-06-29 | Shigeori Takenaka | Method of, device for, and chip of detecting gene |
EP1373574A4 (en) | 2001-03-30 | 2007-01-03 | Ge Healthcare Bio Sciences Ab | P450 single nucleotide polymorphism biochip analysis |
US7202028B2 (en) * | 2001-09-24 | 2007-04-10 | The University Of North Carolina At Chapel Hill | Methods for the electrochemical detection of multiple target compounds |
US20050118616A1 (en) | 2002-08-16 | 2005-06-02 | Kawashima Tadashi R. | Amplification of target nucleotide sequence without polymerase chain reaction |
US7258978B2 (en) | 2002-11-06 | 2007-08-21 | Geneohm Sciences | Electrochemical method to measure DNA attachment to an electrode surface in the presence of molecular oxygen |
US20040086892A1 (en) | 2002-11-06 | 2004-05-06 | Crothers Donald M. | Universal tag assay |
US20040086895A1 (en) | 2002-11-06 | 2004-05-06 | Crothers Donald M. | Method of electrochemical detection of somatic cell mutations |
ATE456678T1 (en) | 2003-11-10 | 2010-02-15 | Geneohm Sciences Inc | NUCLEIC ACID DETECTION METHOD WITH INCREASED SENSITIVITY |
WO2005049848A2 (en) | 2003-11-12 | 2005-06-02 | Geneohm Sciences, Inc. | Nucleic acid hybridization methods |
-
2003
- 2003-05-02 US US10/429,291 patent/US7258978B2/en not_active Expired - Fee Related
-
2004
- 2004-04-30 WO PCT/US2004/013514 patent/WO2004099433A2/en active Application Filing
-
2007
- 2007-08-08 US US11/836,046 patent/US7615348B2/en not_active Expired - Lifetime
-
2009
- 2009-09-29 US US12/569,866 patent/US7879554B2/en not_active Expired - Fee Related
Non-Patent Citations (2)
Title |
---|
"Gene Characterization Kits", STRATAGENE CATALOG., 1988, pages 39, XP002937918 * |
STEEL A.B.: "Electrochemical Quantitation of DNA Immobilized on Gold", ANAL. CHEM., vol. 70, 1998, pages 4670 - 4677, XP002960497 * |
Also Published As
Publication number | Publication date |
---|---|
US7879554B2 (en) | 2011-02-01 |
US20040086894A1 (en) | 2004-05-06 |
US20100018876A1 (en) | 2010-01-28 |
US7615348B2 (en) | 2009-11-10 |
US20080026397A1 (en) | 2008-01-31 |
WO2004099433A2 (en) | 2004-11-18 |
US7258978B2 (en) | 2007-08-21 |
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