WO2005011947A3 - Image processing method and system for microfluidic devices - Google Patents

Image processing method and system for microfluidic devices Download PDF

Info

Publication number
WO2005011947A3
WO2005011947A3 PCT/US2004/024591 US2004024591W WO2005011947A3 WO 2005011947 A3 WO2005011947 A3 WO 2005011947A3 US 2004024591 W US2004024591 W US 2004024591W WO 2005011947 A3 WO2005011947 A3 WO 2005011947A3
Authority
WO
WIPO (PCT)
Prior art keywords
image
image processing
processing method
state
method includes
Prior art date
Application number
PCT/US2004/024591
Other languages
French (fr)
Other versions
WO2005011947A2 (en
WO2005011947A9 (en
Inventor
Colin Jon Taylor
Gang Sun
Simant Dube
Original Assignee
Fluidigm Corp
Colin Jon Taylor
Gang Sun
Simant Dube
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fluidigm Corp, Colin Jon Taylor, Gang Sun, Simant Dube filed Critical Fluidigm Corp
Priority to AU2004261655A priority Critical patent/AU2004261655A1/en
Priority to EP04757388A priority patent/EP1667829A4/en
Priority to CA002532530A priority patent/CA2532530A1/en
Priority to JP2006522086A priority patent/JP2007506943A/en
Publication of WO2005011947A2 publication Critical patent/WO2005011947A2/en
Publication of WO2005011947A9 publication Critical patent/WO2005011947A9/en
Publication of WO2005011947A3 publication Critical patent/WO2005011947A3/en

Links

Classifications

    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0004—Industrial image inspection
    • G06T7/0008—Industrial image inspection checking presence/absence
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • G06F18/20—Analysing
    • G06F18/21—Design or setup of recognition systems or techniques; Extraction of features in feature space; Blind source separation
    • G06F18/213—Feature extraction, e.g. by transforming the feature space; Summarisation; Mappings, e.g. subspace methods
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/20—Analysis of motion
    • G06T7/254—Analysis of motion involving subtraction of images
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/30—Determination of transform parameters for the alignment of images, i.e. image registration
    • G06T7/33—Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
    • G06V10/77—Processing image or video features in feature spaces; using data integration or data reduction, e.g. principal component analysis [PCA] or independent component analysis [ICA] or self-organising maps [SOM]; Blind source separation
    • G06V10/7715—Feature extraction, e.g. by transforming the feature space, e.g. multi-dimensional scaling [MDS]; Mappings, e.g. subspace methods
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/693—Acquisition
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing

Abstract

A method for processing an image of a micro fluidic device. The method includes receiving a first image of a micro fluidic device. The first image corresponds to a first state. Additionally, the method includes receiving a second image of the micro fluidic device. The second image corresponds to a second state. Moreover, the method includes transforming the first image and the second image into a third coordinate space (520). Also, the method includes obtaining a third image based on at least information associated (540) with the transformed first image and the transformed second image, and processing the third image to obtain information (550) associated with the first state and the second state.
PCT/US2004/024591 2003-07-28 2004-07-28 Image processing method and system for microfluidic devices WO2005011947A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2004261655A AU2004261655A1 (en) 2003-07-28 2004-07-28 Image processing method and system for microfluidic devices
EP04757388A EP1667829A4 (en) 2003-07-28 2004-07-28 Image processing method and system for microfluidic devices
CA002532530A CA2532530A1 (en) 2003-07-28 2004-07-28 Image processing method and system for microfluidic devices
JP2006522086A JP2007506943A (en) 2003-07-28 2004-07-28 Image processing method and system for microfluidic devices

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49071203P 2003-07-28 2003-07-28
US60/490,712 2003-07-28

Publications (3)

Publication Number Publication Date
WO2005011947A2 WO2005011947A2 (en) 2005-02-10
WO2005011947A9 WO2005011947A9 (en) 2006-10-26
WO2005011947A3 true WO2005011947A3 (en) 2007-12-13

Family

ID=34115428

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/024591 WO2005011947A2 (en) 2003-07-28 2004-07-28 Image processing method and system for microfluidic devices

Country Status (7)

Country Link
US (2) US7583853B2 (en)
EP (1) EP1667829A4 (en)
JP (1) JP2007506943A (en)
AU (1) AU2004261655A1 (en)
CA (1) CA2532530A1 (en)
SG (1) SG145697A1 (en)
WO (1) WO2005011947A2 (en)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221654B1 (en) 1996-09-25 2001-04-24 California Institute Of Technology Method and apparatus for analysis and sorting of polynucleotides based on size
CA2721172C (en) 1999-06-28 2012-04-10 California Institute Of Technology Microfabricated elastomeric valve and pump systems
US7144616B1 (en) 1999-06-28 2006-12-05 California Institute Of Technology Microfabricated elastomeric valve and pump systems
US7306672B2 (en) 2001-04-06 2007-12-11 California Institute Of Technology Microfluidic free interface diffusion techniques
US7459022B2 (en) * 2001-04-06 2008-12-02 California Institute Of Technology Microfluidic protein crystallography
US7195670B2 (en) 2000-06-27 2007-03-27 California Institute Of Technology High throughput screening of crystallization of materials
US8709153B2 (en) 1999-06-28 2014-04-29 California Institute Of Technology Microfludic protein crystallography techniques
US20050118073A1 (en) * 2003-11-26 2005-06-02 Fluidigm Corporation Devices and methods for holding microfluidic devices
US7867763B2 (en) 2004-01-25 2011-01-11 Fluidigm Corporation Integrated chip carriers with thermocycler interfaces and methods of using the same
US7351376B1 (en) 2000-06-05 2008-04-01 California Institute Of Technology Integrated active flux microfluidic devices and methods
EP1334347A1 (en) 2000-09-15 2003-08-13 California Institute Of Technology Microfabricated crossflow devices and methods
EP1343973B2 (en) 2000-11-16 2020-09-16 California Institute Of Technology Apparatus and methods for conducting assays and high throughput screening
US7691333B2 (en) 2001-11-30 2010-04-06 Fluidigm Corporation Microfluidic device and methods of using same
EP1463796B1 (en) 2001-11-30 2013-01-09 Fluidigm Corporation Microfluidic device and methods of using same
EP1499706A4 (en) 2002-04-01 2010-11-03 Fluidigm Corp Microfluidic particle-analysis systems
EP1551753A2 (en) 2002-09-25 2005-07-13 California Institute Of Technology Microfluidic large scale integration
US8220494B2 (en) 2002-09-25 2012-07-17 California Institute Of Technology Microfluidic large scale integration
JP5695287B2 (en) 2002-10-02 2015-04-01 カリフォルニア インスティテュート オブ テクノロジー Nucleic acid analysis of microfluids
US7604965B2 (en) 2003-04-03 2009-10-20 Fluidigm Corporation Thermal reaction device and method for using the same
US8828663B2 (en) 2005-03-18 2014-09-09 Fluidigm Corporation Thermal reaction device and method for using the same
CA2526368A1 (en) 2003-05-20 2004-12-02 Fluidigm Corporation Method and system for microfluidic device and imaging thereof
US20050171428A1 (en) * 2003-07-21 2005-08-04 Gabor Fichtinger Registration of ultrasound to fluoroscopy for real time optimization of radiation implant procedures
SG145697A1 (en) * 2003-07-28 2008-09-29 Fluidigm Corp Image processing method and system for microfluidic devices
US7407799B2 (en) 2004-01-16 2008-08-05 California Institute Of Technology Microfluidic chemostat
WO2005072353A2 (en) 2004-01-25 2005-08-11 Fluidigm Corporation Crystal forming devices and systems and methods for making and using the same
JP4911722B2 (en) 2004-06-07 2012-04-04 フルイディグム コーポレイション Optical lens system and method for microfluidic devices
JP2008522795A (en) * 2004-12-03 2008-07-03 カリフォルニア インスティチュート オブ テクノロジー Microfluidic device with chemical reaction circuit
WO2006060748A2 (en) 2004-12-03 2006-06-08 California Institute Of Technology Microfluidic sieve valves
WO2006127191A2 (en) 2005-04-20 2006-11-30 Fluidigm Corporation Analysis engine and database for manipulating parameters for fluidic systems on a chip
US20070054293A1 (en) * 2005-08-30 2007-03-08 California Institute Of Technology Microfluidic chaotic mixing systems and methods
EP1938101A2 (en) * 2005-09-13 2008-07-02 Fluidigm Corporation Microfluidic assay devices and methods
FR2897703B1 (en) * 2006-02-20 2008-04-25 Univ Grenoble 1 AUTOMATIC DETECTION OF A SURGICAL TOOL ON AN IMAGE PROVIDED BY A MEDICAL IMAGING SYSTEM
US7815868B1 (en) 2006-02-28 2010-10-19 Fluidigm Corporation Microfluidic reaction apparatus for high throughput screening
US8828661B2 (en) 2006-04-24 2014-09-09 Fluidigm Corporation Methods for detection and quantification of nucleic acid or protein targets in a sample
US8050516B2 (en) * 2006-09-13 2011-11-01 Fluidigm Corporation Methods and systems for determining a baseline during image processing
US8055034B2 (en) * 2006-09-13 2011-11-08 Fluidigm Corporation Methods and systems for image processing of microfluidic devices
EP1901235B1 (en) * 2006-09-15 2019-08-14 Honda Research Institute Europe GmbH Free style deformation (FSD)
US7593560B2 (en) * 2006-11-30 2009-09-22 Canon U.S. Life Sciences, Inc. Systems and methods for monitoring the amplification and dissociation behavior of DNA molecules
WO2008067552A2 (en) * 2006-11-30 2008-06-05 Fluidigm Corporation Method and apparatus for biological sample analysis
US8157434B2 (en) * 2007-01-19 2012-04-17 Fluidigm Corporation High efficiency and high precision microfluidic devices and methods
US8016260B2 (en) 2007-07-19 2011-09-13 Formulatrix, Inc. Metering assembly and method of dispensing fluid
BRPI0816393A2 (en) 2007-09-07 2015-03-03 Fluidigm Corp METHOD FOR DETERMINING THE NUMBER OF COPIES REGARDING A TARGET POLINUCLEOTIDE SEQUENCE IN A GENOME OF AN INDIVIDUAL
EP2050395A1 (en) * 2007-10-18 2009-04-22 Paracelsus Medizinische Privatuniversität Methods for improving image quality of image detectors, and systems therefor
WO2009100449A1 (en) 2008-02-08 2009-08-13 Fluidigm Corporation Dynamic array assay methods
US8125640B2 (en) * 2008-03-03 2012-02-28 Wisconsin Alumni Research Foundation Automated analysis system for detection and quantification of biomolecules by measurement of changes in liquid crystal orientation
CN102056838B (en) 2008-04-11 2013-07-03 弗卢丁公司 Microfluidic device and methods
WO2010011852A1 (en) 2008-07-25 2010-01-28 Fluidigm Corporation Method and system for manufacturing integrated fluidic chips
WO2010017210A1 (en) 2008-08-07 2010-02-11 Fluidigm Corporation Microfluidic mixing and reaction systems for high efficiency screening
FR2935802B1 (en) * 2008-09-05 2012-12-28 Horiba Abx Sas METHOD AND DEVICE FOR CLASSIFYING, VISUALIZING AND EXPLORING BIOLOGICAL DATA
JP5287178B2 (en) * 2008-11-27 2013-09-11 富士通セミコンダクター株式会社 Defect review device
US8058630B2 (en) 2009-01-16 2011-11-15 Fluidigm Corporation Microfluidic devices and methods
US8100293B2 (en) 2009-01-23 2012-01-24 Formulatrix, Inc. Microfluidic dispensing assembly
US8553040B2 (en) * 2009-06-30 2013-10-08 Apple Inc. Fingerprinting of fragment shaders and use of same to perform shader concatenation
US8551787B2 (en) * 2009-07-23 2013-10-08 Fluidigm Corporation Microfluidic devices and methods for binary mixing
TW201110955A (en) * 2009-09-25 2011-04-01 Univ Nat Taiwan Gait training device
SG169918A1 (en) 2009-10-02 2011-04-29 Fluidigm Corp Microfluidic devices with removable cover and methods of fabrication and application
KR101532314B1 (en) * 2009-10-27 2015-06-29 삼성전자주식회사 Quality control method and apparatus of microfluidic device
CA2782181A1 (en) 2009-11-30 2011-06-03 Fluidigm Corporation Microfluidic device regeneration
US8693762B2 (en) * 2010-09-14 2014-04-08 The Regents Of The University Of California Inertial particle focusing flow cytometer
US9353406B2 (en) 2010-10-22 2016-05-31 Fluidigm Corporation Universal probe assay methods
US9168531B2 (en) 2011-03-24 2015-10-27 Fluidigm Corporation Method for thermal cycling of microfluidic samples
US9644231B2 (en) 2011-05-09 2017-05-09 Fluidigm Corporation Nucleic acid detection using probes
CN108342453A (en) 2011-05-09 2018-07-31 富鲁达公司 Detection of nucleic acids based on probe
US8717673B2 (en) * 2011-05-28 2014-05-06 Board Of Trustees Of The University Of Illinois Simple ultra-stable stage with built-in fiduciary markers for fluorescence nanoscopy
US9019363B2 (en) * 2011-07-25 2015-04-28 Mad City Labs, Inc. Microscope stability using a single optical path and image detector
US9558268B2 (en) * 2014-08-20 2017-01-31 Mitsubishi Electric Research Laboratories, Inc. Method for semantically labeling an image of a scene using recursive context propagation
CN113075113A (en) 2014-12-09 2021-07-06 伯克利之光生命科技公司 Automated detection and repositioning of micro-objects in microfluidic devices
KR20190091298A (en) 2016-12-01 2019-08-05 버클리 라잇츠, 인크. Automated Detection and Repositioning of Micro-Objects in Microfluidic Devices
US10408852B2 (en) * 2017-04-26 2019-09-10 Lawrence Livermore National Security, Llc Automated control of microfluidic devices based on machine learning
CN110376171B (en) * 2019-07-15 2021-11-19 上海理工大学 Transmission type fluorescence detection imaging system applied to dPCR detector
WO2021011944A2 (en) * 2019-07-18 2021-01-21 Essenlix Corporation Imaging based homogeneous assay
DE102020202528A1 (en) 2020-02-27 2021-09-02 Robert Bosch Gesellschaft mit beschränkter Haftung Method for analyzing a structure within a fluidic system
WO2021178889A1 (en) * 2020-03-05 2021-09-10 The Trustees Of Columbia University In The City Of New York Three-dimensional dosimetry procedures, methods and devices, and optical ct scanner apparatus which utilizes fiber optic taper for collimated images
US20220101183A1 (en) * 2020-09-29 2022-03-31 International Business Machines Corporation Feature processing for machine learning
EP4306213A1 (en) * 2022-07-14 2024-01-17 Sartorius Stedim Biotech GmbH Method for producing a roll of membrane units

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912984A (en) * 1996-12-19 1999-06-15 Cognex Corporation Method and apparatus for in-line solder paste inspection
US6081577A (en) * 1998-07-24 2000-06-27 Wake Forest University Method and system for creating task-dependent three-dimensional images
US6728424B1 (en) * 2000-09-15 2004-04-27 Koninklijke Philips Electronics, N.V. Imaging registration system and method using likelihood maximization

Family Cites Families (126)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3570515A (en) 1969-06-19 1971-03-16 Foxboro Co Aminar stream cross-flow fluid diffusion logic gate
NL7102074A (en) 1971-02-17 1972-08-21
FR2287606A1 (en) 1974-10-08 1976-05-07 Pegourie Jean Pierre PNEUMATIC LOGIC CIRCUITS AND THEIR INTEGRATED CIRCUITS
JPS5941169B2 (en) 1975-12-25 1984-10-05 シチズン時計株式会社 Elastomer
US4119388A (en) * 1977-06-23 1978-10-10 Armitage Harry J Machine tool
US4153855A (en) 1977-12-16 1979-05-08 The United States Of America As Represented By The Secretary Of The Army Method of making a plate having a pattern of microchannels
US4245673A (en) 1978-03-01 1981-01-20 La Telemechanique Electrique Pneumatic logic circuit
US4373527B1 (en) 1979-04-27 1995-06-27 Univ Johns Hopkins Implantable programmable medication infusion system
US4434704A (en) 1980-04-14 1984-03-06 Halliburton Company Hydraulic digital stepper actuator
US4575681A (en) 1982-11-12 1986-03-11 Teleco Oilfield Services Inc. Insulating and electrode structure for a drill string
US4662710A (en) 1982-12-03 1987-05-05 Amp Incorporated Method and apparatus for breaking an optical fiber
US4581624A (en) 1984-03-01 1986-04-08 Allied Corporation Microminiature semiconductor valve
JPH07104855B2 (en) 1985-03-28 1995-11-13 インターナショナル・ビジネス・マシーンズ・コーポレーション Numerical simulation device
US5088515A (en) 1989-05-01 1992-02-18 Kamen Dean L Valve system with removable fluid interface
US4948564A (en) 1986-10-28 1990-08-14 Costar Corporation Multi-well filter strip and composite assemblies
US4990216A (en) 1987-10-27 1991-02-05 Fujitsu Limited Process and apparatus for preparation of single crystal of biopolymer
US5354695A (en) 1992-04-08 1994-10-11 Leedy Glenn J Membrane dielectric isolation IC fabrication
US4898582A (en) 1988-08-09 1990-02-06 Pharmetrix Corporation Portable infusion device assembly
US4992312A (en) 1989-03-13 1991-02-12 Dow Corning Wright Corporation Methods of forming permeation-resistant, silicone elastomer-containing composite laminates and devices produced thereby
CH679555A5 (en) 1989-04-11 1992-03-13 Westonbridge Int Ltd
DE69011631T2 (en) 1989-06-14 1995-03-23 Westonbridge Int Ltd MICRO PUMP.
US5171132A (en) 1989-12-27 1992-12-15 Seiko Epson Corporation Two-valve thin plate micropump
DE4006152A1 (en) 1990-02-27 1991-08-29 Fraunhofer Ges Forschung MICROMINIATURIZED PUMP
US5096388A (en) 1990-03-22 1992-03-17 The Charles Stark Draper Laboratory, Inc. Microfabricated pump
SE470347B (en) 1990-05-10 1994-01-31 Pharmacia Lkb Biotech Microstructure for fluid flow systems and process for manufacturing such a system
EP0465229B1 (en) 1990-07-02 1994-12-28 Seiko Epson Corporation Micropump and process for manufacturing a micropump
US5164558A (en) 1991-07-05 1992-11-17 Massachusetts Institute Of Technology Micromachined threshold pressure switch and method of manufacture
JP3328300B2 (en) 1991-07-18 2002-09-24 アイシン精機株式会社 Fluid control device
DE4143343C2 (en) 1991-09-11 1994-09-22 Fraunhofer Ges Forschung Microminiaturized, electrostatically operated micromembrane pump
US5265327A (en) 1991-09-13 1993-11-30 Faris Sadeg M Microchannel plate technology
US5637469A (en) 1992-05-01 1997-06-10 Trustees Of The University Of Pennsylvania Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
DE4220077A1 (en) 1992-06-19 1993-12-23 Bosch Gmbh Robert Micro-pump for delivery of gases - uses working chamber warmed by heating element and controlled by silicon wafer valves.
US5364742A (en) 1992-09-21 1994-11-15 International Business Machines Corporation Micro-miniature structures and method of fabrication thereof
US5477474A (en) 1992-10-29 1995-12-19 Altera Corporation Computer logic simulation with dynamic modeling
JP2812629B2 (en) 1992-11-25 1998-10-22 宇宙開発事業団 Crystal growth cell
US5290240A (en) 1993-02-03 1994-03-01 Pharmetrix Corporation Electrochemical controlled dispensing assembly and method for selective and controlled delivery of a dispensing fluid
US5400741A (en) 1993-05-21 1995-03-28 Medical Foundation Of Buffalo, Inc. Device for growing crystals
US5681024A (en) 1993-05-21 1997-10-28 Fraunhofer-Gesellschaft zur Forderung der angerwanden Forschung e.V. Microvalve
SE501713C2 (en) 1993-09-06 1995-05-02 Pharmacia Biosensor Ab Diaphragm-type valve, especially for liquid handling blocks with micro-flow channels
US5642015A (en) 1993-07-14 1997-06-24 The University Of British Columbia Elastomeric micro electro mechanical systems
US5659171A (en) 1993-09-22 1997-08-19 Northrop Grumman Corporation Micro-miniature diaphragm pump for the low pressure pumping of gases
CH689836A5 (en) 1994-01-14 1999-12-15 Westonbridge Int Ltd Micropump.
JPH07311834A (en) * 1994-05-19 1995-11-28 Toshiba Medical Eng Co Ltd Image processor and its aid
DE4433894A1 (en) 1994-09-22 1996-03-28 Fraunhofer Ges Forschung Method and device for controlling a micropump
DE69531430T2 (en) 1994-10-07 2004-07-01 Bayer Corp. relief valve
US5500071A (en) 1994-10-19 1996-03-19 Hewlett-Packard Company Miniaturized planar columns in novel support media for liquid phase analysis
US5571410A (en) 1994-10-19 1996-11-05 Hewlett Packard Company Fully integrated miniaturized planar liquid sample handling and analysis device
US5788468A (en) 1994-11-03 1998-08-04 Memstek Products, Llc Microfabricated fluidic devices
US5665070A (en) 1995-01-19 1997-09-09 I-Flow Corporation Infusion pump with magnetic bag compression
US5588430A (en) 1995-02-14 1996-12-31 University Of Florida Research Foundation, Inc. Repeat fixation for frameless stereotactic procedure
JP3094880B2 (en) 1995-03-01 2000-10-03 住友金属工業株式会社 Method for controlling crystallization of organic compound and solid state element for controlling crystallization used therein
US5775371A (en) 1995-03-08 1998-07-07 Abbott Laboratories Valve control
US5876187A (en) 1995-03-09 1999-03-02 University Of Washington Micropumps with fixed valves
US5932100A (en) 1995-06-16 1999-08-03 University Of Washington Microfabricated differential extraction device and method
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
CA2183478C (en) 1995-08-17 2004-02-24 Stephen A. Carter Digital gas metering system using tri-stable and bi-stable solenoids
US6130098A (en) 1995-09-15 2000-10-10 The Regents Of The University Of Michigan Moving microdroplets
JPH09153131A (en) * 1995-11-30 1997-06-10 Hitachi Ltd Method and device for processing picture information and picture information integrating system
US5705018A (en) 1995-12-13 1998-01-06 Hartley; Frank T. Micromachined peristaltic pump
KR100207410B1 (en) 1995-12-19 1999-07-15 전주범 Fabrication method for lightpath modulation device
US5660370A (en) 1996-03-07 1997-08-26 Integrated Fludics, Inc. Valve with flexible sheet member and two port non-flexing backer member
US5885470A (en) 1997-04-14 1999-03-23 Caliper Technologies Corporation Controlled fluid transport in microfabricated polymeric substrates
US5942443A (en) 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
CA2259395C (en) 1996-07-15 2002-03-05 Sumitomo Metal Industries, Ltd. Equipment for crystal growth and crystal-growing method using the same
US6136212A (en) 1996-08-12 2000-10-24 The Regents Of The University Of Michigan Polymer-based micromachining for microfluidic devices
US5738799A (en) 1996-09-12 1998-04-14 Xerox Corporation Method and materials for fabricating an ink-jet printhead
US5854684A (en) 1996-09-26 1998-12-29 Sarnoff Corporation Massively parallel detection
US5971355A (en) 1996-11-27 1999-10-26 Xerox Corporation Microdevice valve structures to fluid control
US6376971B1 (en) 1997-02-07 2002-04-23 Sri International Electroactive polymer electrodes
EP0991928A2 (en) 1997-06-27 2000-04-12 Immunetics Rapid flow-through binding assay apparatus and method
US6529612B1 (en) 1997-07-16 2003-03-04 Diversified Scientific, Inc. Method for acquiring, storing and analyzing crystal images
US6073482A (en) 1997-07-21 2000-06-13 Ysi Incorporated Fluid flow module
US5932799A (en) 1997-07-21 1999-08-03 Ysi Incorporated Microfluidic analyzer module
US5876675A (en) 1997-08-05 1999-03-02 Caliper Technologies Corp. Microfluidic devices and systems
JPH1185997A (en) * 1997-09-03 1999-03-30 Canon Inc Image processor
TW352471B (en) 1997-09-20 1999-02-11 United Microelectronics Corp Method for preventing B-P-Si glass from subsiding
US5836750A (en) 1997-10-09 1998-11-17 Honeywell Inc. Electrostatically actuated mesopump having a plurality of elementary cells
US5842787A (en) 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
AU1522299A (en) 1997-11-12 1999-05-31 California Institute Of Technology Micromachined parylene membrane valve and pump
US6174675B1 (en) 1997-11-25 2001-01-16 Caliper Technologies Corp. Electrical current for controlling fluid parameters in microchannels
WO1999036714A2 (en) 1998-01-20 1999-07-22 Triconex, Incorporated Two out of three voting solenoid arrangement
AU3491299A (en) 1998-04-14 1999-11-01 Lumenal Technologies, L.P. Test cartridge with a single inlet port
US6246330B1 (en) 1998-05-29 2001-06-12 Wyn Y. Nielsen Elimination-absorber monitoring system
WO2000000678A1 (en) 1998-06-26 2000-01-06 University Of Washington Crystallization media
RU2143343C1 (en) 1998-11-03 1999-12-27 Самсунг Электроникс Ко., Лтд. Microinjector and microinjector manufacture method
ATE357656T1 (en) 1999-04-06 2007-04-15 Univ Alabama Res Found DEVICE FOR SCREENING CRYSTALIZATION CONDITIONS IN CRYSTAL GROWING SOLUTIONS
EP1183059A1 (en) 1999-06-08 2002-03-06 Medical Research Group, Inc. Method and apparatus for infusing liquids using a chemical reaction in an implanted infusion device
US6296673B1 (en) 1999-06-18 2001-10-02 The Regents Of The University Of California Methods and apparatus for performing array microcrystallizations
US7217321B2 (en) 2001-04-06 2007-05-15 California Institute Of Technology Microfluidic protein crystallography techniques
US7052545B2 (en) 2001-04-06 2006-05-30 California Institute Of Technology High throughput screening of crystallization of materials
US7459022B2 (en) 2001-04-06 2008-12-02 California Institute Of Technology Microfluidic protein crystallography
US7244402B2 (en) 2001-04-06 2007-07-17 California Institute Of Technology Microfluidic protein crystallography
US7306672B2 (en) 2001-04-06 2007-12-11 California Institute Of Technology Microfluidic free interface diffusion techniques
US7195670B2 (en) 2000-06-27 2007-03-27 California Institute Of Technology High throughput screening of crystallization of materials
DE19933614C1 (en) 1999-07-17 2000-11-30 Moeller Gmbh Contact system for current-limiting load switch has 2-armed contact arm carrying contact pieces cooperating with contact pieces of fixed contact rails fitted to pivot axis via elongate slot
DE60037433T2 (en) 1999-07-20 2008-12-04 Sri International, Menlo Park Electroactive polymer generators
US6977145B2 (en) 1999-07-28 2005-12-20 Serono Genetics Institute S.A. Method for carrying out a biochemical protocol in continuous flow in a microreactor
EP1206697A2 (en) 1999-08-02 2002-05-22 Emerald Biostructures Inc. Method and system for creating a crystallization results database
AU5121801A (en) 2000-03-31 2001-10-15 Micronics Inc Protein crystallization in microfluidic structures
US7867763B2 (en) 2004-01-25 2011-01-11 Fluidigm Corporation Integrated chip carriers with thermocycler interfaces and methods of using the same
US7351376B1 (en) 2000-06-05 2008-04-01 California Institute Of Technology Integrated active flux microfluidic devices and methods
US6829753B2 (en) 2000-06-27 2004-12-07 Fluidigm Corporation Microfluidic design automation method and system
US6885982B2 (en) 2000-06-27 2005-04-26 Fluidigm Corporation Object oriented microfluidic design method and system
JP3542550B2 (en) 2000-07-19 2004-07-14 本田技研工業株式会社 Method of forming fuel cell seal
US6863791B1 (en) * 2000-09-11 2005-03-08 Spectrumedix Llc Method for in-situ calibration of electrophoretic analysis systems
US6508988B1 (en) 2000-10-03 2003-01-21 California Institute Of Technology Combinatorial synthesis system
JP3943022B2 (en) * 2000-12-01 2007-07-11 株式会社荏原製作所 Board inspection equipment
JP2002228606A (en) * 2001-01-31 2002-08-14 Hitachi Ltd Electron beam circuit pattern inspecting method and apparatus therefor
AU2002307152A1 (en) 2001-04-06 2002-10-21 California Institute Of Technology Nucleic acid amplification utilizing microfluidic devices
CA2442914A1 (en) 2001-04-06 2002-10-17 California Institute Of Technology High throughput screening of crystallization of materials
US20030005308A1 (en) * 2001-05-30 2003-01-02 Rathbun Paul L. Method and system for globally restricting client access to a secured web site
US6797056B2 (en) 2001-06-08 2004-09-28 Syrrx, Inc. Microfluidic method employing delivery of plural different fluids to same lumen
US6847153B1 (en) 2001-06-13 2005-01-25 The United States Of America As Represented By The Secretary Of The Navy Polyurethane electrostriction
US20030027225A1 (en) 2001-07-13 2003-02-06 Caliper Technologies Corp. Microfluidic devices and systems for separating components of a mixture
US7075162B2 (en) 2001-08-30 2006-07-11 Fluidigm Corporation Electrostatic/electrostrictive actuation of elastomer structures using compliant electrodes
US7123569B2 (en) * 2001-09-04 2006-10-17 Imation Corp. Optical data storage medium
US7192629B2 (en) 2001-10-11 2007-03-20 California Institute Of Technology Devices utilizing self-assembled gel and method of manufacture
US7312085B2 (en) 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
US7059348B2 (en) 2002-05-13 2006-06-13 Fluidigm Corporation Drug delivery system
US7476363B2 (en) 2003-04-03 2009-01-13 Fluidigm Corporation Microfluidic devices and methods of using same
US7666361B2 (en) 2003-04-03 2010-02-23 Fluidigm Corporation Microfluidic devices and methods of using same
WO2004094020A2 (en) 2003-04-17 2004-11-04 Fluidigm Corporation Crystal growth devices and systems, and methods for using same
CA2526368A1 (en) 2003-05-20 2004-12-02 Fluidigm Corporation Method and system for microfluidic device and imaging thereof
SG145697A1 (en) 2003-07-28 2008-09-29 Fluidigm Corp Image processing method and system for microfluidic devices
US7413712B2 (en) 2003-08-11 2008-08-19 California Institute Of Technology Microfluidic rotary flow reactor matrix
WO2005072353A2 (en) 2004-01-25 2005-08-11 Fluidigm Corporation Crystal forming devices and systems and methods for making and using the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912984A (en) * 1996-12-19 1999-06-15 Cognex Corporation Method and apparatus for in-line solder paste inspection
US6081577A (en) * 1998-07-24 2000-06-27 Wake Forest University Method and system for creating task-dependent three-dimensional images
US6728424B1 (en) * 2000-09-15 2004-04-27 Koninklijke Philips Electronics, N.V. Imaging registration system and method using likelihood maximization

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEN ET AL.: "Gray-scale photolithography using microfluidic photomasks", PNAS, vol. 100, no. 4, 18 February 2003 (2003-02-18), pages 1499 - 1504, XP008107017 *

Also Published As

Publication number Publication date
EP1667829A2 (en) 2006-06-14
CA2532530A1 (en) 2005-02-10
JP2007506943A (en) 2007-03-22
WO2005011947A2 (en) 2005-02-10
US20100119154A1 (en) 2010-05-13
WO2005011947A9 (en) 2006-10-26
AU2004261655A1 (en) 2005-02-10
US7583853B2 (en) 2009-09-01
SG145697A1 (en) 2008-09-29
US7792345B2 (en) 2010-09-07
US20050282175A1 (en) 2005-12-22
EP1667829A4 (en) 2008-12-10

Similar Documents

Publication Publication Date Title
WO2005011947A3 (en) Image processing method and system for microfluidic devices
EP1515282A3 (en) Storage apparatus and access system
WO2006002210A3 (en) Input device feature
WO2003071410A3 (en) Gesture recognition system using depth perceptive sensors
EP1281665A3 (en) Systems with high density packing of micromachines
WO2002099593A8 (en) A process for synchronizing data between remotely located devices and a central computer system
WO2001065518A3 (en) System and method for using real-world images for providing routing directions
WO2004010249A3 (en) System and method for utilizing profile information
EP1398697A3 (en) Extending operating system functionality for an application
EP1429188A3 (en) Lithographic apparatus and device manufacturing method
EP1465073A3 (en) Architecture for distributed computing system and automated design, deployment, and management of distributed applications
WO2006113291A3 (en) Registration of applications and complimentary features for interactive user interfaces
WO2007139603A3 (en) Integrated verification and screening system
WO2006047586A3 (en) Enhanced user assistance
EP1267219A3 (en) Image processing device for processing image data by judging a detected and expanded medium-density field as a non-character edge field
EP1324182A3 (en) System and method for peripheral device virtual functionality overlay
AU2002360203A1 (en) Device, system and method for image based size analysis
WO2002015604A3 (en) Mobile data communication system
WO2003102751A3 (en) Method of measuring the movement of an input device
EP1152326A3 (en) A technique for providing continuous speech recognition as an alternative input device to limited processing power devices
IL172707A0 (en) Data input device, system using the device, and methods for operating such systems
EP1439488A3 (en) Image processing system, method and program
WO2003023701A3 (en) Operating device
WO2004109594A3 (en) System and method for rule based object navigation
WO2007075948A3 (en) System and method for interface navigation

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
ENP Entry into the national phase

Ref document number: 2532530

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2006522086

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2004261655

Country of ref document: AU

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2004757388

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2004261655

Country of ref document: AU

Date of ref document: 20040728

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2004261655

Country of ref document: AU

WWP Wipo information: published in national office

Ref document number: 2004757388

Country of ref document: EP