WO2005014026A3 - Use of cxcl6 chemokine in the prevention or repair of cartilage defects - Google Patents
Use of cxcl6 chemokine in the prevention or repair of cartilage defects Download PDFInfo
- Publication number
- WO2005014026A3 WO2005014026A3 PCT/BE2004/000117 BE2004000117W WO2005014026A3 WO 2005014026 A3 WO2005014026 A3 WO 2005014026A3 BE 2004000117 W BE2004000117 W BE 2004000117W WO 2005014026 A3 WO2005014026 A3 WO 2005014026A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- repair
- cxcl6
- prevention
- cartilage
- cartilage defects
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/195—Chemokines, e.g. RANTES
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2533124A CA2533124C (en) | 2003-08-12 | 2004-08-12 | Use of cxcl6 chemokine in the prevention or repair of cartilage defects |
PL04761478T PL1653994T3 (en) | 2003-08-12 | 2004-08-12 | Use of cxcl6 chemokine in the prevention or repair of cartilage defects |
NZ545702A NZ545702A (en) | 2003-08-12 | 2004-08-12 | Use of CXCL6 chemokine in the prevention or repair of cartilage defects |
AT04761478T ATE449608T1 (en) | 2003-08-12 | 2004-08-12 | USE OF CXCL6 CHEMOKINE IN PREVENTING OR REPAIRING CARTILAGE DEFECTS |
DE602004024312T DE602004024312D1 (en) | 2003-08-12 | 2004-08-12 | USE OF CXCL6 CHEMOKIN IN THE PREVENTION OR REPAIR OF CARTILAGE DEFECTS |
DK04761478.9T DK1653994T3 (en) | 2003-08-12 | 2004-08-12 | Use of CXCL6 chemokine in the prevention or recovery of cartilage defects |
US10/595,072 US7485310B2 (en) | 2003-08-12 | 2004-08-12 | Use of CXCL6 chemokine in the prevention or repair of cartilage defects |
JP2006522851A JP4920412B2 (en) | 2003-08-12 | 2004-08-12 | Use of CXCL6 chemokine in the prevention or recovery of cartilage tissue defects |
EP04761478A EP1653994B1 (en) | 2003-08-12 | 2004-08-12 | Use of cxcl6 chemokine in the prevention or repair of cartilage defects |
AU2004262451A AU2004262451B2 (en) | 2003-08-12 | 2004-08-12 | Use of CXCL6 chemokine in the prevention or repair of cartilage defects |
NO20060464A NO338152B1 (en) | 2003-08-12 | 2006-01-30 | The use of CXCL6 chemokine in the prevention or repair of cartilage defects |
IL173544A IL173544A (en) | 2003-08-12 | 2006-02-05 | Use of cxcl6 in the preparation of a medicament for the promotion of cartilage and/or bone formation |
HK06105628.3A HK1085656A1 (en) | 2003-08-12 | 2006-05-16 | Use of cxcl6 chemokine in the prevention or repair of cartilage defects |
US12/345,369 US7842502B2 (en) | 2003-08-12 | 2008-12-29 | Use of CXCL6 chemokine for inducing precursor cells into chondrocytes |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49451603P | 2003-08-12 | 2003-08-12 | |
US60/494,516 | 2003-08-12 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/595,072 A-371-Of-International US7485310B2 (en) | 2003-08-12 | 2004-08-12 | Use of CXCL6 chemokine in the prevention or repair of cartilage defects |
US12/345,369 Division US7842502B2 (en) | 2003-08-12 | 2008-12-29 | Use of CXCL6 chemokine for inducing precursor cells into chondrocytes |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005014026A2 WO2005014026A2 (en) | 2005-02-17 |
WO2005014026A3 true WO2005014026A3 (en) | 2005-03-17 |
Family
ID=34135345
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/BE2004/000117 WO2005014026A2 (en) | 2003-08-12 | 2004-08-12 | Use of cxcl6 chemokine in the prevention or repair of cartilage defects |
Country Status (16)
Country | Link |
---|---|
US (2) | US7485310B2 (en) |
EP (1) | EP1653994B1 (en) |
JP (1) | JP4920412B2 (en) |
AT (1) | ATE449608T1 (en) |
AU (1) | AU2004262451B2 (en) |
CA (1) | CA2533124C (en) |
DE (1) | DE602004024312D1 (en) |
DK (1) | DK1653994T3 (en) |
ES (1) | ES2337469T3 (en) |
HK (1) | HK1085656A1 (en) |
IL (1) | IL173544A (en) |
NO (1) | NO338152B1 (en) |
NZ (1) | NZ545702A (en) |
PL (1) | PL1653994T3 (en) |
RU (1) | RU2363491C2 (en) |
WO (1) | WO2005014026A2 (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050222687A1 (en) * | 2004-04-02 | 2005-10-06 | Gordana Vunjak-Novakovic | Cartilage implant assembly and method for implantation |
US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
US7901457B2 (en) * | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
US20090291112A1 (en) * | 2003-05-16 | 2009-11-26 | Truncale Katherine G | Allograft osteochondral plug combined with cartilage particle mixture |
US20090149893A1 (en) * | 2007-12-05 | 2009-06-11 | Semler Eric J | Cancellous Bone Implant for Cartilage Repair |
US20080220044A1 (en) * | 2007-03-06 | 2008-09-11 | Semler Eric J | Cancellous construct with support ring for repair of osteochondral defects |
US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
CA2623106C (en) | 2005-09-19 | 2013-12-24 | Histogenics Corporation | Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof |
US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
WO2009111069A1 (en) * | 2008-03-05 | 2009-09-11 | Musculoskeletal Transplant Foundation | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
EA018959B1 (en) | 2008-09-22 | 2013-12-30 | Аркариос Б.В. | Carboxyethylated cyclodextrin polysulfates useful as medicaments |
GB0820492D0 (en) | 2008-11-07 | 2008-12-17 | Sportcell | Cell compositions and uses thereof |
MX2012001207A (en) * | 2009-07-27 | 2012-05-08 | Baxter Int | Blood coagulation protein conjugates. |
US8808682B2 (en) * | 2009-10-23 | 2014-08-19 | Rnl Bio Co., Ltd | Method for inducing migration of adipose-derived adult stem cells |
US8687070B2 (en) * | 2009-12-22 | 2014-04-01 | Apple Inc. | Image capture device having tilt and/or perspective correction |
KR101793806B1 (en) | 2013-03-15 | 2017-11-03 | 더블유.엘. 고어 앤드 어소시에이트스, 인코포레이티드 | Aqueous delivery system for low surface energy structures |
CA2902226A1 (en) * | 2013-03-29 | 2014-10-02 | Merrimack Pharmaceuticals, Inc. | Compositions and methods for treating osteolytic bone disorders |
US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
CN116904520B (en) * | 2023-09-13 | 2024-01-09 | 中国人民解放军军事科学院军事医学研究院 | Method for preparing recombinant cartilage progenitor cells, obtained recombinant cartilage progenitor cells and application |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5786217A (en) * | 1994-05-05 | 1998-07-28 | Genzyme Corporation | Methods and compositions for the repair of articular cartilage defects in mammals |
US6410268B1 (en) * | 1996-03-18 | 2002-06-25 | Human Genome Sciences, Inc. | Polynucleotides encoding chemokine alpha-3 |
US6413511B1 (en) * | 1990-12-20 | 2002-07-02 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Cartilage alterations by administering to joints chondrocytes comprising a heterologous polynucleotide |
US20020123483A1 (en) * | 2001-03-05 | 2002-09-05 | Geeta Saxena | IL-8 receptor ligands - drugs for inflammatory and autoimmune diseases |
EP1312614A1 (en) * | 2001-11-16 | 2003-05-21 | GenOdyssee | Polynucleotides and polypeptides of the GCP-2 gene |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5840524A (en) * | 1992-11-27 | 1998-11-24 | Stichting Rega Vzw | Granulocyte chemotactic protein |
GB9502022D0 (en) | 1995-02-02 | 1995-03-22 | Abuljadayel Ilham M S | A method for preparing lymphohaematopoietic progenitor cells |
DE19814405C2 (en) * | 1998-03-31 | 2000-03-02 | Schastak Astrid | Porphyrins and their use as photosensitizers |
JP2005500847A (en) * | 2001-08-24 | 2005-01-13 | アドバンスド セル テクノロジー、インコーポレイテッド | Screening assay for identification of differentiation inducers and preparation of differentiated cells for cell therapy |
JP2003199816A (en) * | 2002-01-10 | 2003-07-15 | Takehisa Matsuda | Auxiliary material for regenerating cartilaginous tissue, kit for regenerating cartilaginous tissue and method for regenerating cartilaginous tissue |
BR0312786A (en) * | 2002-07-26 | 2005-05-03 | Ajinomoto Kk | DNA, recombinant DNA, transformed cell, and methods for producing a peptide-forming enzyme, and for producing a dipeptide |
WO2005038012A2 (en) * | 2003-06-27 | 2005-04-28 | Ethicon Incorporated | Cartilage and bone repair and regeneration using postpartum-derived cells |
-
2004
- 2004-08-12 DK DK04761478.9T patent/DK1653994T3/en active
- 2004-08-12 AU AU2004262451A patent/AU2004262451B2/en not_active Revoked
- 2004-08-12 WO PCT/BE2004/000117 patent/WO2005014026A2/en active Search and Examination
- 2004-08-12 CA CA2533124A patent/CA2533124C/en not_active Expired - Fee Related
- 2004-08-12 RU RU2006107536/14A patent/RU2363491C2/en not_active IP Right Cessation
- 2004-08-12 PL PL04761478T patent/PL1653994T3/en unknown
- 2004-08-12 NZ NZ545702A patent/NZ545702A/en not_active IP Right Cessation
- 2004-08-12 JP JP2006522851A patent/JP4920412B2/en not_active Expired - Fee Related
- 2004-08-12 DE DE602004024312T patent/DE602004024312D1/en active Active
- 2004-08-12 ES ES04761478T patent/ES2337469T3/en active Active
- 2004-08-12 AT AT04761478T patent/ATE449608T1/en active
- 2004-08-12 US US10/595,072 patent/US7485310B2/en not_active Expired - Fee Related
- 2004-08-12 EP EP04761478A patent/EP1653994B1/en active Active
-
2006
- 2006-01-30 NO NO20060464A patent/NO338152B1/en not_active Application Discontinuation
- 2006-02-05 IL IL173544A patent/IL173544A/en active IP Right Grant
- 2006-05-16 HK HK06105628.3A patent/HK1085656A1/en not_active IP Right Cessation
-
2008
- 2008-12-29 US US12/345,369 patent/US7842502B2/en not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6413511B1 (en) * | 1990-12-20 | 2002-07-02 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Cartilage alterations by administering to joints chondrocytes comprising a heterologous polynucleotide |
US5786217A (en) * | 1994-05-05 | 1998-07-28 | Genzyme Corporation | Methods and compositions for the repair of articular cartilage defects in mammals |
US6410268B1 (en) * | 1996-03-18 | 2002-06-25 | Human Genome Sciences, Inc. | Polynucleotides encoding chemokine alpha-3 |
US20020123483A1 (en) * | 2001-03-05 | 2002-09-05 | Geeta Saxena | IL-8 receptor ligands - drugs for inflammatory and autoimmune diseases |
EP1312614A1 (en) * | 2001-11-16 | 2003-05-21 | GenOdyssee | Polynucleotides and polypeptides of the GCP-2 gene |
Non-Patent Citations (1)
Title |
---|
WUYTS ANJA ET AL: "The CXC chemokine GCP-2/CXCL6 is predominantly induced in mesenchymal cells by interleukin-1beta and is down-regulated by interferon-gamma: Comparison with interleukin-8/CXCL8.", LABORATORY INVESTIGATION, vol. 83, no. 1, January 2003 (2003-01-01), pages 23 - 34, XP002314496, ISSN: 0023-6837 * |
Also Published As
Publication number | Publication date |
---|---|
CA2533124C (en) | 2014-01-28 |
US7485310B2 (en) | 2009-02-03 |
ATE449608T1 (en) | 2009-12-15 |
US20060246031A1 (en) | 2006-11-02 |
RU2006107536A (en) | 2006-08-10 |
PL1653994T3 (en) | 2010-05-31 |
CA2533124A1 (en) | 2005-02-17 |
RU2363491C2 (en) | 2009-08-10 |
AU2004262451A1 (en) | 2005-02-17 |
AU2004262451B2 (en) | 2009-11-26 |
DE602004024312D1 (en) | 2010-01-07 |
NO20060464L (en) | 2006-04-20 |
ES2337469T3 (en) | 2010-04-26 |
HK1085656A1 (en) | 2006-09-01 |
EP1653994B1 (en) | 2009-11-25 |
IL173544A0 (en) | 2006-07-05 |
EP1653994A2 (en) | 2006-05-10 |
IL173544A (en) | 2013-12-31 |
NO338152B1 (en) | 2016-08-01 |
JP2007501807A (en) | 2007-02-01 |
WO2005014026A2 (en) | 2005-02-17 |
JP4920412B2 (en) | 2012-04-18 |
US20090117652A1 (en) | 2009-05-07 |
DK1653994T3 (en) | 2010-03-15 |
NZ545702A (en) | 2008-08-29 |
US7842502B2 (en) | 2010-11-30 |
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